PF00001.16_7tm_1_seed 64 434 !Q:11,11|15,20|51,57|59,59|61,61|66,68|110,113|143,144|151,162|166,166|169,178|180,180|195,195|222,222|228,359|395,395|399,409|411,411 Q:0,10|12,14|21,50|58,58|60,60|62,65|69,109|114,142|145,150|163,165|167,168|179,179|181,194|196,221|223,227|360,394|396,398|410,410|412,433 HHHHHHHHHHH?TTT?----?HHHHHHHHHHHHHHHHHHTHHHHHHHHHHH-------S-S?SSHH---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHH??--HHHHHHHHHHHHHHHHHHHHHHHHTTTTB??SHHHHH------------HHH?TT?????-----B?HHHHHHHHHHHTHH-HHHHHHHHHHHHHHHHHHHHHSTTSS?TTHHH------------------------------------------------------------------------------------------------------------------------------------HHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHH?TTS-----------S?HHHHHHHHHHHHHHHHHHHHHT 4EJ4|A PF00002.19_7tm_2_seed 31 372 !Q:15,15|30,30|35,35|38,38|60,60|65,103|111,114|147,154|156,157|184,198|203,216|219,219|221,225|231,234|265,270|273,273|275,275|278,278|283,315|334,335|341,345|363,366 Q:0,14|16,29|31,34|36,37|39,59|61,64|104,110|115,146|155,155|158,183|199,202|217,218|220,220|226,230|235,264|271,272|274,274|276,277|279,282|316,333|336,340|346,362|367,371 HHHHHHHHHHHHHHH-HHHHHHHHHHHSSS-SSTT?SH-HHHTTTHHHHHHHHHHHHHHH-HHHT?????????????????---------------------?THHHHTT----TTTHHHHHHHHHHHHHHHHHHHHHTTIIIIIT?-----??S?-SSGGGGTSTTGGGHHHHTTSHHHHHH---------------HHHS?------------?SS-S???-?SHHHH----HHTHHHHHHHHHHHHHHHHHHHHHHTHHHH------TT?S?TT?HHHH---------------------------------HHHHHTTTSSHHHHHTTT--TTTTS?????HHHHHHHHHHHHHHHHT----HHHHH 4K5Y|A PF00004.24_AAA_seed 207 252 !Q:4,5|9,9|21,35|37,49|51,73|75,75|79,79|81,81|85,85|88,107|118,118|120,123|127,135|137,137|150,152|155,162|165,167|170,170|186,187|190,214|216,217|226,228|233,233|238,238|244,244|249,251 Q:0,3|6,8|10,20|36,36|50,50|74,74|76,78|80,80|82,84|86,87|108,117|119,119|124,126|136,136|138,149|153,154|163,164|168,169|171,185|188,189|215,215|218,225|229,232|234,237|239,243|245,248 EEEE??TTS?HHHHHHHHHHH---------------H-------------T----??-----------------E-EEE?S?SST-TS---------------?????HHHHHHHHHH-H----HTT?--------S-EEEEETTHHHHT???ST--------TS??-TT?HHHHHHHHHHHHHHT??SS-------------------------S?-EEEEEEES?--TTTS?GGGG-STTSS?EEEE??? 3PXG|A PF00005.22_ABC_tran_seed 55 274 !Q:8,8|11,11|18,18|34,42|47,87|90,90|93,94|99,99|102,107|112,112|140,144|148,148|163,171|175,182|192,221|224,224|227,240|244,244|250,251|262,263 Q:0,7|9,10|12,17|19,33|43,46|88,89|91,92|95,98|100,101|108,111|113,139|145,147|149,162|172,174|183,191|222,223|225,226|241,243|245,249|252,261|264,273 EEEEEEEE?TT?EEEEEE?TTSSHHHHHHHHHTS???-----?EEEE-----------------------------------------EE?TT??EEEE?SS--????TTSB-HHHHHHHHTHHHHHHHHHHHHHHHHTT?----TTS?HHHHHHHHHHHHHH?????????HHH--------HHHHHHHTT???---------------------------TT?BT--------------TTS?HHHHH--HHHHHHHHHH??SEEEEESTTT 1XMI|A PF00006.20_ATP-synt_ab_seed 157 756 !Q:0,0|2,2|10,11|15,15|22,22|39,63|67,70|75,484|487,488|500,513|517,524|528,550|553,553|560,560|564,564|566,568|579,579|589,589|592,593|598,602|606,606|623,628|632,633|638,640|650,650|652,686|691,691|699,701|704,704|708,708|710,712|729,731|739,739|741,741|743,743|747,750 Q:1,1|3,9|12,14|16,21|23,38|64,66|71,74|485,486|489,499|514,516|525,527|551,552|554,559|561,563|565,565|569,578|580,588|590,591|594,597|603,605|607,622|629,631|634,637|641,649|651,651|687,690|692,698|702,703|705,707|709,709|713,728|732,738|740,740|742,742|744,746|751,755 ?S?HHHHHHS??BTT?EEEEEE?TTSSHHHHHHHHHHHS--------------------?---?SEE----EEEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ES??HHHHHHHHHTT--------------THH--------HHH-----------------------HT-EEEEEE?TTS?H---HHHHHHHHHH-HHHHHHHHT-TT?-EEEE-----EEE?HHHHHHHHHHHHHHTT?--???SSS??TTHH---HHHHHHHTT?S??---------------------------------STTS?EEEEEEE---EE?SSS?S-??HHHHHHHHHSSEEEEE--?HHHHHTT?S-S?EEE----EEEEE 1PV4|A PF00007.17_Cys_knot_seed 24 112 !Q:8,10|16,17|20,20|22,23|38,43|47,47|50,53|68,68|71,72|75,77|91,92|94,95|103,105|107,108|111,111 Q:0,7|11,15|18,19|21,21|24,37|44,46|48,49|54,67|69,70|73,74|78,90|93,93|96,102|106,106|109,110 SBBSEEEE---EEEEE??TT?S??EEEEEEEEEEEEEE??--??BTT?SS????EEEEEEEEEEEEEE?TT??SS???EEEEEEEEEEEEE--E??TTTEEEE???S??SS? 1FL7|B PF00008.22_EGF_seed 71 50 !Q:3,10|13,15|20,23|30,31|36,37|40,44 Q:0,2|11,12|16,19|24,29|32,35|38,39|45,49 TSS?----???TT--?EEEE??-?EETTEE??EEEE??TT-----EESTT 1CCF|A PF00009.22_GTP_EFTU_seed 216 521 !Q:2,4|10,10|29,34|37,40|42,42|45,57|69,76|78,80|85,121|130,130|132,133|135,135|138,139|147,148|152,152|163,181|196,203|207,208|212,212|217,227|229,231|246,246|250,251|256,256|260,261|275,275|279,302|305,306|308,309|331,331|339,339|343,347|354,360|370,371|375,375|378,380|383,383|385,402|406,507|509,509|519,520 Q:0,1|5,9|11,28|35,36|41,41|43,44|58,68|77,77|81,84|122,129|131,131|134,134|136,137|140,146|149,151|153,162|182,195|204,206|209,211|213,216|228,228|232,245|247,249|252,255|257,259|262,274|276,278|303,304|307,307|310,330|332,338|340,342|348,353|361,369|372,374|376,377|381,382|384,384|403,405|508,508|510,518 HT???EEEEE?TTTHHHHHHHHHHHHHHS??????TT---?S-SS?------------SSSHHHHHHTB-----???S???EEEE-------------------------------------ETTEEEEE?S??S?SS-?HHHHHHH--HHH?SEEEEEEETT--------??-------??HHHHHHHHHHHHTT??------EEE--EEE?TTSS-----------S-??HHHHHHHHHHHTSS?EEE??EEES?TTT??EEEETTTTEEEEE?STT---------------------???EE??B??HHHHHHHHHHHHHHHHHHHTT?HHHHHHH-HHT-????HHHHHH-------HHHHHHHTT??EEE-EE???TT?T------------------THH------------------------------------------------------------------------------------------------------H-HHHHHHHHS?? 1NVU|Q PF00010.21_HLH_seed 164 93 !Q:20,20|30,30|32,69|73,76 Q:0,19|21,29|31,31|70,72|77,92 SSHHHHHHHHHHHHHHHHHH-HHHHTTSSS-S--------------------------------------TTS?-??TTHHHHHHHHHHHHHH 2QL2|A PF00011.16_HSP20_seed 37 118 !Q:4,4|14,14|17,19|22,22|33,34|41,50|53,53|58,64|71,71|74,78|82,82|87,87|98,102|105,117 Q:0,3|5,13|15,16|20,21|23,32|35,40|51,52|54,57|65,70|72,73|79,81|83,86|88,97|103,104 EEEE?SSEEEEEEE?TT??-GG-GEEEEEETTT--EEEEEE??--??????TT?EEEE???????EEEEEE?SS--???GGG?EEEE-ETTEEEEEEE?????TT-----???????? 2H50|A PF00012.15_HSP70_seed 33 692 !Q:0,0|5,6|23,25|29,29|34,34|39,39|43,43|57,57|64,64|71,71|85,85|88,88|92,92|103,105|108,109|112,112|128,128|134,134|136,140|147,147|150,151|167,167|190,195|206,206|209,209|219,219|224,224|237,237|258,258|261,263|267,267|305,306|323,324|343,345|349,349|374,374|376,377|379,379|382,382|401,406|408,413|416,420|430,430|436,436|440,440|447,447|451,452|457,459|470,470|477,480|490,492|494,495|498,499|501,501|505,506|511,511|515,515|524,524|527,528|535,535|540,542|549,582|622,626|631,631|636,639|654,657|661,667|682,682|690,691 Q:1,4|7,22|26,28|30,33|35,38|40,42|44,56|58,63|65,70|72,84|86,87|89,91|93,102|106,107|110,111|113,127|129,133|135,135|141,146|148,149|152,166|168,189|196,205|207,208|210,218|220,223|225,236|238,257|259,260|264,266|268,304|307,322|325,342|346,348|350,373|375,375|378,378|380,381|383,400|407,407|414,415|421,429|431,435|437,439|441,446|448,450|453,456|460,469|471,476|481,489|493,493|496,497|500,500|502,504|507,510|512,514|516,523|525,526|529,534|536,539|543,548|583,621|627,630|632,635|640,653|658,660|668,681|683,689 ?EEEE??SSEEEEEEEETTEEEE???TTS?SSEE?EEEE?TTS?EEESHHHHTTTTT?GGGEEE?GGGTTT?BSSSTTHHHHHHH?SS?EEE?TTSBEEEEET---TE--EE?HHHHHHHHHHHHHHH-HHHHH?S?--??EEEEEE?TT??HHHHHHHHHHHHTTT?EEEEEEEHHHHHHHHTTTTSSS------SEEEEEEEEE?SS?EEEEEEEEE?TTTS?EEEEEEEEEESS?SGGGTHHHHHHHHHHHHHHH-HS?-?STT?HHHHHHHHHHHHHHHHHTTSSSEEEEEEEEEEEETTE--EEEEEEEEEHHHHHTT??STTGGGTSHHHHHHHTTT??-TTT?SEEEEESGGGGSHHHHHHHHHHHS-S??B?SS?TTTHHHHHHHHHHTTTTT------S??????SB?????EEEEETTTE-EEEEE?TTB?SSEEEE-EEE??SSTT??-EEEEEEEESS?SBGGGS----EEEEEEEEE???S??TT-?S?EEE--EEEE?TTS?EEEEEEET-TT??EEEEEE?TTSS-??HHHHHH----------------------------------HHHHHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----GGGS?HHHH----HHHHHHHHHHHHHT----TSS?------HHHHHHHHHHHHTT?HHHHHHH?? 1NGH|A PF00013.24_KH_1_seed 396 102 !Q:7,7|11,12|18,18|23,23|33,35|37,37|41,48|52,60|62,68|76,76|78,79|81,82|84,84|93,99 Q:0,6|8,10|13,17|19,22|24,32|36,36|38,40|49,51|61,61|69,75|77,77|80,80|83,83|85,92|100,101 EEEEEEE-TTT--GGGGT?GGGH-HHHHHHHHH-??E-EEE------??TTS--------?S-------SEEEEEE-E--E-?H-HHHHHHHH-------HH 3KRM|A PF00014.18_Kunitz_BPTI_seed 147 81 !Q:4,11|13,26|28,30|37,40|48,48|53,53|57,60|62,66|68,68|80,80 Q:0,3|12,12|27,27|31,36|41,47|49,52|54,56|61,61|67,67|69,79 GGGS??-???--S-??---?------?E---EEEEEE----TTTTEEE-EEEE?SSS??--S-----S?BSSHHHHHHHH? 1Y62|A PF00015.16_MCPsignal_seed 9 243 !Q:14,27|81,82|120,133|181,184|198,211|239,239|241,242 Q:0,13|28,80|83,119|134,180|185,197|212,238|240,240 HHHHHHHHHHHHHH--------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTST--TTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHH----HHHHHHHHHHHHH--------------HHHHHHHHHHHHHHHHHHHHHHHHTTT?B?? 1QU7|A PF00016.15_RuBisCO_large_seed 16 320 !Q:0,0|10,14|17,17|23,23|28,30|46,46|51,52|55,55|62,62|84,85|91,93|109,109|112,112|123,123|139,141|147,147|156,157|163,163|175,176|181,185|188,189|205,205|209,210|217,217|219,219|222,222|225,228|236,237|249,250|258,264|267,267|290,291|296,297|309,309|316,319 Q:1,9|15,16|18,22|24,27|31,45|47,50|53,54|56,61|63,83|86,90|94,108|110,111|113,122|124,138|142,146|148,155|158,162|164,174|177,180|186,187|190,204|206,208|211,216|218,218|220,221|223,224|229,235|238,248|251,257|265,266|268,289|292,295|298,308|310,315 ?HHHHHHHHT---??SS?EEEEE?SSSS???HHHHHHHHHHHHHTT?SEEE??TT?SSBTTB?HHHHHHHHHHHHHHHHHHHSS??EEEEE???SSHHHHHHHHHHHHH-TT?SEEEEEHHHH?HHHHHHHHHHHHHHT--?EEEEE?TTHHHHHS-?SSSEE?HHHHHHHHHHH??SEEE????-TT??HHHHHHHHHHHHHHH?SEE??BGGGTB?S?EE?TT????EEEEESS??GGGHHHHHHHH?-SSEEEEE???????TT?HHHHHHHHHHHHHHHHHHHHTT??HHHH--HHHHHHHHHHH?HHHHHT???? 1RBA|A PF00017.19_SH2_seed 58 109 !Q:1,2|5,6|8,12|22,25|28,29|34,35|37,37|41,41|46,48|50,51|55,56|60,63|66,67|71,72|80,86|96,97 Q:0,0|3,4|7,7|13,21|26,27|30,33|36,36|38,40|42,45|49,49|52,54|57,59|64,65|68,70|73,79|87,95|98,108 S??BS??H-----HHHHHHHHT----TT??TTEE??B?BSS-SSSB---B??EEE??BTT----TB??EEE??BEEETTT-------EEEEETTEE--ESSHHHHHHHH 1Z3K|A PF00018.23_SH3_1_seed 61 56 !Q:4,4|6,7|10,11|15,16|18,18|21,21|28,28|32,34|45,49 Q:0,3|5,5|8,9|12,14|17,17|19,20|22,27|29,31|35,44|50,55 EESS?B??SS--TTB??B?TT?EEEEEE?SSS---SEEEEEETTT---??EEEEEG 1MUZ|A PF00019.15_TGF_beta_seed 20 116 !Q:0,1|7,8|14,14|18,18|25,25|30,31|37,38|41,42|48,52|65,67|69,69|73,76|81,82|93,93|96,98|115,115 Q:2,6|9,13|15,17|19,24|26,29|32,36|39,40|43,47|53,64|68,68|70,72|77,80|83,92|94,95|99,114 ??BSEEE??EEETT-TTT?GGGEEE?SEEE??EEESB??SS??TTTTB?----HHHHHHHHHHHT--?T-TTS????EEEE--EEEEEEEEEE?TT??-EEEEEEEEEEEEEEEE? 2GH0|C PF00020.13_TNFR_c6_seed 37 50 !Q:0,1|4,5|8,9|11,12|15,17|20,20|23,28|33,33|38,39|42,42|45,47 Q:2,3|6,7|10,10|13,14|18,19|21,22|29,32|34,37|40,41|43,44|48,49 ??TT--EE??S--SB?-?SS?EE?-????GGGT?EEEE??BT-TB??-EE 2HEY|R PF00021.16_UPAR_LY6_seed 40 109 !Q:4,4|7,7|17,17|22,23|26,27|29,32|37,52|58,58|63,69|80,82|85,86|88,98|101,101 Q:0,3|5,6|8,16|18,21|24,25|28,28|33,36|53,57|59,62|70,79|83,84|87,87|99,100|102,108 EEEB?SS-SSSSSSSSS?EEEE??TT??E----EEEE????????----????EEEEE?SSSS-------SSSHHHHTSS-??SS??E-----------EE-ESSSGGG 1CDR|A PF00022.14_Actin_seed 28 695 !Q:0,5|11,11|25,25|27,36|42,42|45,49|54,93|95,95|101,103|107,109|111,111|119,119|122,122|127,127|129,129|145,145|147,157|159,196|200,200|206,206|209,210|226,227|245,245|247,264|272,272|275,275|287,287|291,291|296,296|306,306|313,333|335,361|363,366|382,385|391,405|413,424|428,428|431,436|438,441|443,443|445,445|448,497|502,502|513,517|519,519|525,561|574,576|586,586|611,626|628,628|631,639|642,643|645,647|663,663|665,665|669,669|682,682|685,687|693,695 Q:6,10|12,24|26,26|37,41|43,44|50,53|94,94|96,100|104,106|110,110|112,118|120,121|123,126|128,128|130,144|146,146|158,158|197,199|201,205|207,208|211,225|228,244|246,246|265,271|273,274|276,286|288,290|292,295|297,305|307,312|334,334|362,362|367,381|386,390|406,412|425,427|429,430|437,437|442,442|444,444|446,447|498,501|503,512|518,518|520,524|562,573|577,585|587,610|627,627|629,630|640,641|644,644|648,662|664,664|666,668|670,681|683,684|688,692 ??????EEEEE?SSEEEEEETTBSS?S----------EEEES?EE-----EESS???????------------------------------???S?EETHH---HHH---T-TTTEEEE?TT-TTSS?S?HHHHHHHHHHHHHTT-T???--------G--------------------------------------GGS?EEEEE?TT??HHHHHHHHHHHHHTS??SEEEEEEHHHHHHHHTT?S------------------SEEEEEE?SS?EEEEEEETTEE?GGG?EEES?SHHHHHHHH-HHHHGG---------------------G---------------------------T????SHHHHHHHHHHHHHH????SSHHH---------------HHHHHHH?-----------STT?EE------E----E?T-TS-----------------------------------------------?--EEEE?THHHHHHHTT-----T?GGGGT????--------------------------------?HHHHHHHHHHTS?--GGGHHHHHT?EEEESGGGGSTTHHHHHHHHHHHH----------------S?TT?-----???EE??T---TTTSHHHHHHHHHHT?T-TTT-TTSEEHHHHHHH?TT---HHHHH??- 1QZ6|A PF00023.25_Ank_seed 1072 59 !Q:1,3|13,35|45,48|51,52|55,57 Q:0,0|4,12|36,44|49,50|53,54|58,58 T???HHHHHHHTT----------------------?HHHHHHHHH----TT??TT???T 1BI8|B PF00024.21_PAN_1_seed 89 158 !Q:1,9|21,27|34,34|36,40|52,56|58,59|61,67|69,71|79,99|108,109|113,135|141,145 Q:0,0|10,20|28,33|35,35|41,51|57,57|60,60|68,68|72,78|100,107|110,112|136,140|146,157 T---------TEEEEEEEEEE?------SSEEEE-E?----SSHHHHHHHHH-----S??S-------S???EEEEEGG---------------------GTEEEEES??TTT-----------------------SEEEE-----EEEEEEEEEHHH 2LL4|M PF00025.16_Arf_seed 20 202 !Q:10,13|15,15|37,37|40,40|44,46|61,65|76,85|103,103|106,107|122,122|127,129|131,131|139,139|145,147|160,167|169,173|175,176|182,182 Q:0,9|14,14|16,36|38,39|41,43|47,60|66,75|86,102|104,105|108,121|123,126|130,130|132,138|140,144|148,159|168,168|174,174|177,181|183,201 HHHHHGGGTT----S?SEEEEEEEETTSSHHHHHHHH?SS?EEE---EEEETTEEEEEEEE-----TTEEEEEEEE??????????GGGGGGEEEEEEEEETT?GG--GHHHHHHHHHHHHT?GGGT---T?EEEEEEE?TTSTT???HHHHHHHHTGGG-------?S-----S??EEEEE?BTTTTBTHHHHHHHHHHHH 1NVU|Q PF00026.18_Asp_seed 23 513 !Q:0,0|22,25|29,31|35,36|38,61|68,69|71,71|75,75|78,78|80,84|86,88|90,90|99,99|127,130|135,139|142,142|150,150|152,152|156,156|160,173|183,184|193,204|211,213|228,237|247,248|255,258|260,260|266,266|269,282|286,286|289,290|295,295|308,310|312,313|335,336|346,375|395,396|410,410|412,413|417,418|421,421|428,430|437,437|444,444|452,452|454,454|458,466|474,478|482,482|488,488|501,501 Q:1,21|26,28|32,34|37,37|62,67|70,70|72,74|76,77|79,79|85,85|89,89|91,98|100,126|131,134|140,141|143,149|151,151|153,155|157,159|174,182|185,192|205,210|214,227|238,246|249,254|259,259|261,265|267,268|283,285|287,288|291,294|296,307|311,311|314,334|337,345|376,394|397,409|411,411|414,416|419,420|422,427|431,436|438,443|445,451|453,453|455,457|467,473|479,481|483,487|489,500|502,512 ?EEEEEEETTTTEEEEEEEETT????EEE---BTT??S?-----------------------GGGGGS??B?GGG?TT?B??-??E---E-EEEETTEE-EEEEEEEEEEEETTEEEEEEEEEEEEE?--?BSHH-----HH?SSSEEEE?S?GGG?GGG-----------???HHHHHTTTT??SSSEEEEE??????--????EEEEET???TTSEEEEEEEEEEE----------EETTEEEEE??EEETTE----E?STTTT?EE--------------EEE?SS??SEEE?HHHHHHHHHHHT???B??HHHHHHHHHTHHHHHHHHHTT??HHHHHHHTT??????????????????????????????HHHHHHHHHHHHHHHHHTT??HHHHHHHHHHHTT?B??SSS??EE?GGGGTT???EEEEET-TEEEEE?HHHHEEE?S?GGG?-------?EEESEEE-????TTS?SEEEE?HHHHTTEEEEEE-TTTTEEEEEEE 1APT|E PF00027.24_cNMP_binding_seed 342 132 !Q:4,4|7,7|11,11|14,20|29,29|36,36|40,40|43,67|73,73|76,76|80,80|86,86|88,97|104,108|111,111|129,129 Q:0,3|5,6|8,10|12,13|21,28|30,35|37,39|41,42|68,72|74,75|77,79|81,85|87,87|98,103|109,110|112,128|130,131 EEEE?TT?EEE?TT??---??EEEEEEES?EEEEEE?TTS?EE-------------------------EEEEE?TT?EES?HHHHS?S--------??SSEEEE-----SS?EEEEEEEHHHHHHTTSS?HH 1ZRD|A PF00028.12_Cadherin_seed 57 129 !Q:8,11|14,14|19,21|23,23|26,27|34,35|44,45|48,48|50,51|55,55|59,59|61,67|71,71|73,73|78,78|85,91|104,110|113,113|116,117 Q:0,7|12,13|15,18|22,22|24,25|28,33|36,43|46,47|49,49|52,54|56,58|60,60|68,70|72,72|74,77|79,84|92,103|111,112|114,115|118,128 EEEEEESS??--TT?EEEE???B?SS?-TTSSSS??EEEEEEEE??SS?S??EEE?TTT?E-------EEE?S?SSSS?SSSSSS-------SEEEEEEEEESG-------GG?TT??EEEEEEEEEEE 3Q2L|A PF00029.14_Connexin_seed 65 124 !Q:0,0|10,10|12,12|15,17|20,20|50,50|54,56|68,68|71,71|88,97|103,106|114,115 Q:1,9|11,11|13,14|18,19|21,49|51,53|57,67|69,70|72,87|98,102|107,113|116,123 ?TTHHHHHHH-S?SS???SS?HHHHHHHHHHHHHHHHHHHHHHTTHHHHT?EES???TTHHHHHHHTT?SS?HHHHHHHHHHHTHHHH----------HHHHH----HHHHHHH--HHHHHTTT 3IZ1|A PF00030.14_Crystall_seed 138 123 !Q:11,12|20,20|22,22|24,25|27,28|31,32|34,34|36,49|57,57|59,59|61,61|72,73|79,83|88,88|93,93|96,98|100,101|104,117|122,122 Q:0,10|13,19|21,21|23,23|26,26|29,30|33,33|35,35|50,56|58,58|60,60|62,71|74,78|84,87|89,92|94,95|99,99|102,103|118,121 EEEEEEEGGGE--EEEEEES-S?B--S??TT--T?S?------------?SEEEEEE-S?E-EEEEETTTEE--EEEEE?----SEEE?SGGG-GT?--S--SS?-----------??EEEE? 1GAM|A PF00031.16_Cystatin_seed 43 107 !Q:0,2|5,6|8,9|29,32|53,54|70,75|77,77|79,80|83,84|86,87|92,93 Q:3,4|7,7|10,28|33,52|55,69|76,76|78,78|81,82|85,85|88,91|94,106 ???EE??T--TSHHHHHHHHHHHHHHHHH?-??SEEEEEEEEEEEEEEEEEEE--EEEEEEEEEEEEEET------T?S??SS??B??STTT??EEEEEEEEEEEGG 3IMA|B PF00032.12_Cytochrom_B_C_seed 114 153 !Q:1,2|5,7|10,13|26,27|30,30|45,50|72,75|77,83|85,87|90,90|92,93|97,97|104,108|123,123|127,131|135,136|138,138|146,146 Q:0,0|3,4|8,9|14,25|28,29|31,44|51,71|76,76|84,84|88,89|91,91|94,96|98,103|109,122|124,126|132,134|137,137|139,145|147,152 B??TT???TT????GGGHHHHHHHHH??TT?HHHHHHHHTTTTSS?-----HHHHHHHHHHHHHHHHHHHHH----H?----??S???GG-G?-HHH-HHHHHH-----HHHHHHHHHHHHTS?SST-----THH--H-HHHHHHH-HHHHHH 1SQB|C PF00033.14_Cytochrom_B_N_seed 92 326 !Q:0,6|9,19|22,22|25,26|37,37|39,41|49,111|113,113|117,118|150,150|152,179|189,204|215,215|230,250|253,254|257,257|273,273|278,282|287,287|296,296|312,325 Q:7,8|20,21|23,24|27,36|38,38|42,48|112,112|114,116|119,149|151,151|180,188|205,214|216,229|251,252|255,256|258,272|274,277|283,286|288,295|297,311 ???????TT-----------HH-HH--HHHHHHHHHH-H---HHHHHHS???---------------------------------------------------------???S?GGG??HHHHHHHHHHHHHHHHHHHHHHHHHHHTTTT?S???-----------??????????????STTTSSSSS????????????????TTTHHHHHHH-HHHHHHHHHHHHTT---------------------TT??SS?GGGHHHHHHHHHHTS?THHH-----HHHH-HHHHHHHH-HHHHHHHHHHHHHHH????-????????? 1SQB|C PF00034.16_Cytochrom_C_seed 237 181 !Q:4,6|10,11|13,21|28,29|33,36|39,76|78,80|83,84|103,104|106,113|117,119|129,164|166,166|180,180 Q:0,3|7,9|12,12|22,27|30,32|37,38|77,77|81,82|85,102|105,105|114,116|120,128|165,165|167,179 HHHH---HTT?-T---------TTHHHH-?TTS????TT--------------------------------------S???TT??HHHHHHHHHHHHHHSSTT??T--------TSS???GGGTTTTTT----------------------------------??H-HHHHHHHHHHHTS? 1R0Q|A PF00035.20_dsrm_seed 110 103 !Q:3,5|10,10|17,21|24,25|34,35|39,41|46,48|53,60|63,63|68,71|76,82|84,84|87,87 Q:0,2|6,9|11,16|22,23|26,33|36,38|42,45|49,52|61,62|64,67|72,75|83,83|85,86|88,102 HHH---HHHH-HHHHHH-----SS??EEEEEEEE??TTS-?-EEEE---EEEE--------TT-EEEE----EEEE-------S-SH-HHHHHHHHHHHHHHH 1T4N|A PF00036.27_EF-hand_1_seed 893 29 !Q:9,9 Q:0,8|10,28 HHHHHHHHH?SSSSSSEEHHHHHHHHHHH 1MUX|A PF00037.22_Fer4_seed 533 24 !Q:3,3|7,11|17,17|20,21 Q:0,2|4,6|12,16|18,19|22,23 EEE?TTT?????THHHH?TT??EE 3MMC|B PF00038.16_Filament_seed 33 384 !Q:0,282|289,291|301,304|378,383 Q:283,288|292,300|305,377 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?----??-----------------------------------------??????????????????????????????????????HHHHHH---HHHHHHHHH----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-??--- 3KLT|A PF00039.13_fn1_seed 20 43 !Q:2,3|6,7|13,14|18,18|21,22|26,27|29,29 Q:0,1|4,5|8,12|15,17|19,20|23,25|28,28|30,42 EE?-TT??EEETT-?EEE?SS?-SSS??E-EEEEETTTTEEEE 1TPN|A PF00040.14_fn2_seed 111 47 !Q:0,1|12,12|14,14|16,16|19,19|22,24|26,27|32,32|39,40|44,47 Q:2,11|13,13|15,15|17,18|20,21|25,25|28,31|33,38|41,43 ??SSEEETTEEE?S?B?TT?SS???E--EESS-SBHHHH??EEE--?- 1CXW|A PF00041.16_fn3_seed 106 117 !Q:0,3|12,15|18,18|25,31|34,35|43,45|51,51|53,64|69,71|73,73|76,80|82,83|88,88|90,92|95,95|103,103|109,113|116,116 Q:4,11|16,17|19,24|32,33|36,42|46,50|52,52|65,68|72,72|74,75|81,81|84,87|89,89|93,94|96,102|104,108|114,115 ???-EEEEEEEE---?SS?EEEEEE??-----SS??SEEEEEE---EETTS?S----------??EEEE---E?TT----?S--EEEE?S?-?TT?EEEEEEE-EEETT-----EE? 3F7P|C PF00042.17_Globin_seed 73 124 !Q:11,21|48,51|60,60|80,80|82,86|88,88|106,111 Q:0,10|22,47|52,59|61,79|81,81|87,87|89,105|112,123 HHHHHHHHHTT-?--------?TTTHHHHHHHHHHHHSGGGGGGGGGG-???SSHHHHHH?HHHHHHHHHHHHHHHHHHT?G-----G-GHHHHTHHHHHHHHHTS---???THHHHHHHHHHH 1R1Y|A PF00043.20_GST_C_seed 58 144 !Q:17,18|29,34|57,83|85,85|90,91|96,97|105,107|114,115|118,126|129,129|142,142 Q:0,16|19,28|35,56|84,84|86,89|92,95|98,104|108,113|116,117|127,128|130,141|143,143 THHHHHHHHHHHHTSSS??HHHHHHHHHH------HHHHHHHHHHHHHHHHHHHHTT???????????????????????????S-STTS??HHHH--TTHHHHT---TGGGGT??HH---------HH?HHHHHHHHHHHT?H 2NTO|A PF00044.19_Gp_dh_N_seed 112 211 !Q:6,7|20,24|26,27|33,33|37,39|41,41|44,45|55,59|67,68|71,71|74,75|78,85|89,90|94,94|98,100|102,102|105,105|108,109|111,112|116,117|119,119|124,127|132,132|136,140|147,147|149,153|157,158|160,160|162,162|170,173|176,183|187,188|193,193|197,198|202,203|207,209 Q:0,5|8,19|25,25|28,32|34,36|40,40|42,43|46,54|60,66|69,70|72,73|76,77|86,88|91,93|95,97|101,101|103,104|106,107|110,110|113,115|118,118|120,123|128,131|133,135|141,146|148,148|154,156|159,159|161,161|163,169|174,175|184,186|189,192|194,196|199,201|204,206|210,210 EEEEEE??SHHHHHHHHHHT-----T?-SSEEE-EEE---E?SS-?HHHHHHHHH-----EETTTEE?-SS?EE--EE--------TTE--EEE-TTE---E-EE-EE??S?-GGG??G-GGGT??--EEEE?SSS?---?BHHHHT-H-----HHH--T-T?SEEEESS?--?BS?-------SEE??TTTS-GGG??TTT??EEE???H 3DMT|A PF00045.14_Hemopexin_seed 76 57 !Q:0,1|9,13|33,36|40,40|43,43|55,55 Q:2,8|14,32|37,39|41,42|44,54|56,56 ??EEEEETT-----TTEEEEEETTEEEEEETTT----TEE?SS?SEEHHHHSTTS?S 1RTG|A PF00046.24_Homeobox_seed 182 67 !Q:0,0|2,2|4,4|7,7|20,22|24,26|29,30|42,46|48,49|66,66 Q:1,1|3,3|5,6|8,19|23,23|27,28|31,41|47,47|50,65 ?S?S?SS?HHHHHHHHHHHH---H--?SS??HHHHHHHHHHH-----T??HHHHHHHHHHHHHHHT? 1AU7|A PF00047.20_ig_seed 52 92 !Q:1,2|10,14|17,18|21,21|31,31|34,36|43,43|47,48|52,52|78,79|82,82|84,84 Q:0,0|3,9|15,16|19,20|22,30|32,33|37,42|44,46|49,51|53,77|80,81|83,83|85,91 T??EEEEEEE-----ES??SS?EEEEEEESS?SS???EEEEEE?SSS??EEE?TTTTGGGTEEEEEETTTEEEEEESS??GG-G?EEEEEEE 3UCR|A PF00048.15_IL8_seed 181 92 !Q:0,5|7,7|10,11|14,17|20,23|28,30|32,32|35,35|38,39|42,42|46,48|53,53|56,61|63,63|65,65|70,70|72,75|84,85|87,88 Q:6,6|8,9|12,13|18,19|24,27|31,31|33,34|36,37|40,41|43,45|49,52|54,55|62,62|64,64|66,69|71,71|76,83|86,86|89,91 ??????E-EE-?SS?--?SS???-GGGE---E-EE-EE??TT-SSS-??EEEE-ET------T-S?EEEE?T----TSHHHHHH--H--HHH 1IKL|A PF00049.13_Insulin_seed 28 176 !Q:1,3|13,13|17,19|22,27|29,35|37,41|44,44|52,52|56,125|128,129|131,131|133,133|135,136|140,140|145,150|152,156|165,167|175,175 Q:0,0|4,12|14,16|20,21|28,28|36,36|42,43|45,51|53,55|126,127|130,130|132,132|134,134|137,139|141,144|151,151|157,164|168,174 S???HHHHHHHHH-HHS---GG------G-??????S----?SS?SSSSSSS?SSS----------------------------------------------------------------------SS??S?S?S??HHH-HHHT------T???--SHHHHTSS???HHHHHHT? 2OM1|1 PF00050.16_Kazal_1_seed 51 66 !Q:4,4|8,8|12,12|16,16|19,26|33,33|42,45|51,51|54,58|64,65 Q:0,3|5,7|9,11|13,15|17,18|27,32|34,41|46,50|52,53|59,63 GGGS?EEE?TTS?EEE?EE---?????EEETTS?EESSHHHH----HHHHH-HH?????EEESS?? 1SGN|I PF00051.13_Kringle_seed 24 85 !Q:2,2|8,13|19,19|22,23|26,27|31,32|34,36|40,40|44,46|48,50|52,53|55,55|58,59|62,63|68,68|73,74|79,79|81,81|84,84 Q:0,1|3,7|14,18|20,21|24,25|28,30|33,33|37,39|41,43|47,47|51,51|54,54|56,57|60,61|64,67|69,72|75,78|80,80|82,83 EE?TTSTT??????BBTTS?BB??TT??SSS??S?-?TTT?TTS???T---T??B?TT??SS-?EEEB-SSTT??EEEB-S?EE? 1NK1|A PF00053.19_Laminin_EGF_seed 72 72 !Q:0,2|6,14|20,20|31,32|38,39|48,48|51,51|57,57|61,64|67,67|70,70 Q:3,5|15,19|21,30|33,37|40,47|49,50|52,56|58,60|65,66|68,69|71,71 ???TTS?--------SEEEE?HHHHHHTTSS??EEEES??TTEESTTS?EE?TTEEE?SSS---?TT?TT?E 4AQT|A PF00054.18_Laminin_G_1_seed 21 181 !Q:3,4|6,6|11,12|15,15|17,17|22,30|51,55|61,62|64,67|71,71|89,89|94,116|120,120|124,134|137,137|143,149|152,155|158,158|160,161|164,165|178,180 Q:0,2|5,5|7,10|13,14|16,16|18,21|31,50|56,60|63,63|68,70|72,88|90,93|117,119|121,123|135,136|138,142|150,151|156,157|159,159|162,163|166,177 EEE??S?EEEE--EE-E?TTSS---------SEEEEEEETTEEEEEEESSS?----EEEEE??S?-??SSS?EEEEEEEETTEEEEEET-TEEE-----------------------EEE?STT???----????SE-EEESS-??----TT????SS?S??SB-?SEEEEEEEESSS??? 1PZ9|A PF00055.12_Laminin_N_seed 9 264 !Q:1,4|11,11|17,17|19,20|26,26|33,33|38,43|50,51|54,55|63,65|71,81|84,88|91,97|118,118|120,123|138,138|148,150|159,160|162,163|166,168|171,173|176,176|179,180|182,182|187,187|195,197|201,202|204,204|226,228|231,233|236,245|252,254 Q:0,0|5,10|12,16|18,18|21,25|27,32|34,37|44,49|52,53|56,62|66,70|82,83|89,90|98,117|119,119|124,137|139,147|151,158|161,161|164,165|169,170|174,175|177,178|181,181|183,186|188,194|198,200|203,203|205,225|229,230|234,235|246,251|255,263 B????EESSTT?GGGEE?S??TTSSS?EEEEEE?SSSS-----?EEEEEE??SS??BTTTBTT???GGGSS???????????EE??---TT?--?-??EEEEEEEEEEEEEEEEEEES-S???-SEEEEEEESSTTSS?EEEEEEESS---TTTTSSSS??S??SS---TT???EE?TT??S?STTT?EEEEESS?--SSS??S?TTSHHHHHHHEEEEEEEEEEE???TT???TT?--------?HHHHTT???EEEEEEEEE 4AQT|A PF00056.18_Ldh_1_N_seed 31 168 !Q:0,0|6,8|23,26|29,38|43,43|48,49|65,65|68,69|74,78|85,85|91,92|94,97|100,106|130,133|139,139|145,148|159,161 Q:1,5|9,22|27,28|39,42|44,47|50,64|66,67|70,73|79,84|86,90|93,93|98,99|107,129|134,138|140,144|149,158|162,167 ?EEEEE??-SHHHHHHHHHHHHH-???SE----------EEEE?SSHH--HHHHHHHHHHTSGGG?SS??EEEE---??GGGGTT?SEEEE??S????SS??-----HHHHHHHHHHHHHHHHHHHHHHT--??SEEEE?SSSHH----HHHHHHHHHH???TTSEEE 8LDH|A PF00057.13_Ldl_recept_a_seed 53 60 !Q:0,59 Q: ????-----??????????-----????-????---???????-----??????--???? 1F8Z|A PF00058.12_Ldl_recept_b_seed 28 56 !Q:12,13|20,20|25,29|34,34|37,45|47,47 Q:0,11|14,19|21,24|30,33|35,36|46,46|48,55 TEEEEEETTTTE--EEEEES?STTS??-??EEEE?SS--------?S?EEEEEEET 3S8V|A PF00059.16_Lectin_C_seed 95 164 !Q:1,1|3,3|13,13|15,17|20,20|23,26|28,31|43,54|57,57|63,69|71,71|76,76|81,83|88,98|100,100|103,111|118,120|125,136|140,140|144,149|151,151|155,156 Q:0,0|2,2|4,12|14,14|18,19|21,22|27,27|32,42|55,56|58,62|70,70|72,75|77,80|84,87|99,99|101,102|112,117|121,124|137,139|141,143|150,150|152,154|157,163 S?B?HHHHHHHHH-H---TT?EE????S----HHHHHHHHHHH-----------?SS?EEEEE-------E?TTSS?EETT???STTS--------???B?TT---??????TTSSSS???EEEE-----------?TTS?EEE------E?TTS-?BEEEEEE 1JSK|A PF00060.21_Lig_chan_seed 44 402 !Q:0,0|22,106|123,136|171,176|184,186|192,192|205,213|226,226|229,257|272,273|294,298|300,302|308,311|314,314|318,319|325,325|356,361|363,363|370,377|381,383|385,386 Q:1,21|107,122|137,170|177,183|187,191|193,204|214,225|227,228|258,271|274,293|299,299|303,307|312,313|315,317|320,324|326,355|362,362|364,369|378,380|384,384|387,401 ?HHHHHHHHHHHHHHHTTGGGT??-???-?????-----?????-----------------------------------------------------??????????HHHHHHHHHHHTTTTS??-????--?????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH???-??SSHHHHH??-SSEEE?BSSSHHHHHHHH??------?HHHHHHHHHHHH?SS--------------------------???BSSHHHHHHHHHTT--TTSEEEEEEHHHHHHHHTST-----T-??EEEES?--?SS?EEE??EEETT?SSHHHHHHHHHHHHHTTHHHHHHHHHHTTS?-----S?SSTTTS--------TTT???S??SHHHHHHHHHHHHHH 3KG2|A PF00061.18_Lipocalin_seed 156 177 !Q:0,0|2,2|12,16|26,27|33,34|39,41|47,49|51,58|62,62|70,71|74,75|77,78|83,83|86,87|92,94|97,101|112,112|123,126|137,137|141,141|148,161|168,168|176,176 Q:1,1|3,11|17,25|28,32|35,38|42,46|50,50|59,61|63,69|72,73|76,76|79,82|84,85|88,91|95,96|102,111|113,122|127,136|138,140|142,147|162,167|169,175 ?E-EEEEEEEES-----HHHHHHHHT??HHHHH--HHHT???EEEEE---E--------ETT-EEEEEEE?-SS??E--EEEE?TT??EEEE-?-TT??---EEEEEEEEET-TEEEEEEEET----TEEEEEEEEE-ETT-EEEEEE--------------EETTEE-EEEEEEE? 1HN2|A PF00062.15_Lys_seed 21 128 !Q:0,0|2,3|16,16|23,23|41,41|64,64|66,66|68,68|72,74|77,78|88,88|119,120 Q:1,1|4,15|17,22|24,40|42,63|65,65|67,67|69,71|75,76|79,87|89,118|121,127 ?B??HHHHHHHHHHTT?TTBTTB?HHHHHHHHHHHHTTBTT?EEEETTTTEEEETTTTEETTTS?B?S?STT???TT??BGGGGGSSS?HHHHHHHHHHHTSTTGGGGSHHHHHHTTTS??GGGTTTS 2ZQ4|A PF00063.16_Myosin_head_seed 24 953 !Q:0,0|8,10|24,24|27,28|40,42|44,45|47,49|60,73|78,80|97,98|103,105|128,129|131,177|180,184|213,213|215,215|223,223|227,227|229,232|240,244|248,250|252,254|257,260|270,271|275,275|281,298|302,302|305,305|308,308|310,313|315,342|345,346|363,364|384,387|389,390|392,396|400,412|414,416|420,420|431,431|442,446|448,455|458,464|495,540|548,556|560,560|594,594|596,605|611,611|615,616|620,621|632,632|635,640|653,653|656,656|658,660|663,663|666,667|670,678|682,682|688,688|691,691|697,697|706,709|719,719|721,722|731,732|734,734|736,811|831,833|838,839|842,844|847,848|851,853|869,870|879,880|896,896|901,901|904,914|927,932|934,938|942,943|945,945|952,952 Q:1,7|11,23|25,26|29,39|43,43|46,46|50,59|74,77|81,96|99,102|106,127|130,130|178,179|185,212|214,214|216,222|224,226|228,228|233,239|245,247|251,251|255,256|261,269|272,274|276,280|299,301|303,304|306,307|309,309|314,314|343,344|347,362|365,383|388,388|391,391|397,399|413,413|417,419|421,430|432,441|447,447|456,457|465,494|541,547|557,559|561,593|595,595|606,610|612,614|617,619|622,631|633,634|641,652|654,655|657,657|661,662|664,665|668,669|679,681|683,687|689,690|692,696|698,705|710,718|720,720|723,730|733,733|735,735|812,830|834,837|840,841|845,846|849,850|854,868|871,878|881,895|897,900|902,903|915,926|933,933|939,941|944,944|946,951 ?SBTTSSS???TTHHHHHHHHHHH-HT??EEEETTEEEEE???S??S-??SHHHHHHHSS??------------SSSS???HHHHHHHHHHHHHHHT??EEEE???STTSSTTHHHHHHHHHHHHHSS??S??????--------------------------------------???TT?????SHHHHHHHHHHHHTTTTEEEETTEEEEE?S?EEEEEEE?SSS?E----EEEEEEE?????GGG---S???TT????THHHHHHHH??HHH-HHHTT??---------------?TTS?SS?TT-S----S???-------------------------TT??HHHHHHHHHHHHHHHT??HHHHHHHHHHHHHHHHTTT??-?B??T-----TTS??-----------B???SHH-HHHHHHHTTS?HHHHHHHHHS?????T--------TS???????HHHHHHHHHHHHHHHHHHHHHHHHHHHTTT?????-------------------------------------????EEEEEEE???????--SSB?HHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHT?S??????????HHHHH-TTS??SSS??HHHHHHHTTS?TT?----?HHHHHHHHHHHT-SS?T---TE-EE?-SS--------?TTT?EEEEE?SS?EEEEE?TTHHHHHH????HHHHHHHHT?S?-HHHHHHHS??T-T????--------------------------------------????????????---------??????????-??HHHHHHHHHHHHHHHHTTS---EEEE??EE???SS??SS???HHHHHHHHHHTTHHH--HHHHHHHS??EEEEHHHHHHHTTTT?TTTS?SS----?----??HHHHHHHHHHTT------T??---TTT??B?SSEEEE? 1BR1|A PF00064.13_Neur_seed 7 486 !Q:0,91|94,96|106,106|114,116|118,118|121,123|125,125|140,141|155,158|161,161|171,172|177,177|191,191|194,194|203,203|207,207|223,223|228,229|231,232|235,238|251,251|255,255|274,275|278,278|280,282|284,284|287,287|298,300|304,304|307,307|324,326|329,330|334,338|341,343|346,346|348,350|352,355|357,362|365,366|370,374|379,379|381,381|393,393|399,399|402,405|418,420|425,426|432,433|437,438|451,451|453,453|457,457|471,482 Q:92,93|97,105|107,113|117,117|119,120|124,124|126,139|142,154|159,160|162,170|173,176|178,190|192,193|195,202|204,206|208,222|224,227|230,230|233,234|239,250|252,254|256,273|276,277|279,279|283,283|285,286|288,297|301,303|305,306|308,323|327,328|331,333|339,340|344,345|347,347|351,351|356,356|363,364|367,369|375,378|380,380|382,392|394,398|400,401|406,417|421,424|427,431|434,436|439,450|452,452|454,456|458,470|483,485 ????????????????????????????????????????????????????????????????????????????????--??????????EE???SEEEEEEEE?HHHHHTT---S?BB???S?EEEEETTEEEEEEE??SSBSSSGGGTTTT????TT?EEEEEETTS??BTTT?EEEEESSSEEEEE?SS?EEEEEEES?TTS?EEEEEESSSEEEEEE?SSSS??B??SS????BTTBEEEEEEEE?SSS?EEEEEEEEETTEEEEEEE??SS?S???S?EE-EEETTEEEEE???SSS?SS?EEEEEETTTTEEEEEE???SS??SSS?????SS?-?SS-S???S?--?S??????EE??TTS----?EEEE?S?SSSSEEEEEEE?TTTTT?TT?-??SEEEEEEEEEEE???EEEE??TTSSS--SEE??EEEEEEEEETTT-S?SSS?EEEEEEEEEEESS????????????GGG 1IVE|A PF00066.12_Notch_seed 53 49 !Q:0,0|6,14|18,18|24,24|29,30|33,34|36,36 Q:1,5|15,17|19,23|25,28|31,32|35,35|37,48 ?TTTTS?--------GGG?GGGTT-TSSS??GG--G?SGGGGGGGGTTS 3ETO|A PF00067.17_p450_seed 50 557 !Q:0,2|4,7|17,17|19,22|24,24|29,29|38,40|50,51|77,79|85,87|92,92|97,98|100,101|124,125|147,154|156,156|176,180|183,183|186,196|210,211|214,215|217,217|224,224|226,226|232,232|244,244|262,263|266,285|295,295|297,300|304,305|308,314|343,343|348,348|364,364|369,380|387,387|406,406|408,409|411,411|414,414|417,420|426,428|432,432|435,435|447,447|452,452|458,459|465,465|469,484|486,489|492,493|496,497|502,502|527,529|532,532|536,540|543,543|549,553 Q:3,3|8,16|18,18|23,23|25,28|30,37|41,49|52,76|80,84|88,91|93,96|99,99|102,123|126,146|155,155|157,175|181,182|184,185|197,209|212,213|216,216|218,223|225,225|227,231|233,243|245,261|264,265|286,294|296,296|301,303|306,307|315,342|344,347|349,363|365,368|381,386|388,405|407,407|410,410|412,413|415,416|421,425|429,431|433,434|436,446|448,451|453,457|460,464|466,468|485,485|490,491|494,495|498,501|503,526|530,531|533,535|541,542|544,548|554,556 ???S?-??TTTTTGGGS?T----T?HHHH-HHHHHHHH--?SEEEEESSS-?EEEEEESHHHHHHHHTTTHHHHBEE???HHHHH---HTTT?SSSS??H--HHHHHHHHHHHHHTSTTSSSSS-?HHHHHHHHHHHHHHHHHTTTT??------B?TTTHHHHHHHHHHHHHHHS????-TT?HH-----------HHHHHHHHHHHHH--HH??S?TTHHHH?T-HHHHH?HHHHHHHHHHH-HHHHHHHHHHHHHHHHS??TT-----------------???SHHHHHHHH-T----SSS??TT-----??HHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHH?HHHHHHHHHHHHHHT-TTTS---------???THHHHT?HHHHHHHHHHHHHHTSST-T-?S?EE?SS---?EEETT---EEE?TT?EEEEEHHHHHT?TTTS-SSTTS??GGGGB?TTS---------------?B-???TT??TT??STTS?SSHHHHHHHHHHHHHHHHHHEEEE--?SS?GGG?????EE?SSSEE?????BEE 3NA1|A PF00068.14_Phospholip_A2_1_seed 37 137 !Q:0,0|13,15|17,17|21,21|26,26|34,35|38,39|56,60|63,68|72,75|78,78|83,84|87,89|91,91|115,117|123,125|130,130|133,136 Q:1,12|16,16|18,20|22,25|27,33|36,37|40,55|61,62|69,71|76,77|79,82|85,86|90,90|92,114|118,122|126,129|131,132 ?HHHHHHHHHHHH--?S?HHH-HTTT?TTTTSSS??SS??SHHHHHHHHHHHHHHH?---?SS-----?TTT????EE?GGGS-?EE??-S?HHHHHHHHHHHHHHHHHHHTGGG??-GGGTT?-?GGGS?SS???? 4H0Q|A PF00069.20_Pkinase_seed 54 476 !Q:9,9|15,16|25,34|42,48|58,76|84,91|94,95|97,100|108,125|131,132|137,138|142,146|150,150|155,170|174,179|200,200|202,211|215,218|226,227|231,231|233,251|254,256|259,259|262,293|297,298|300,303|306,309|312,325|327,327|329,331|349,353|356,362|364,367|369,373|387,387|389,390|400,400|406,411|414,431|436,436|439,440|451,452|459,465 Q:0,8|10,14|17,24|35,41|49,57|77,83|92,93|96,96|101,107|126,130|133,136|139,141|147,149|151,154|171,173|180,199|201,201|212,214|219,225|228,230|232,232|252,253|257,258|260,261|294,296|299,299|304,305|310,311|326,326|328,328|332,348|354,355|363,363|368,368|374,386|388,388|391,399|401,405|412,413|432,435|437,438|441,450|453,458|466,475 EEEEEEEEE?SSEEE--EEEEETTT??--------EEEEEEE???-???HHHHHHHHH-------------------HHHHHHH?-?----?TT--B--??EEEEEEE------------------TTEEE--EEEE??SEE-----HHH-HHHH----------------TSS??---?HHHHHHHHHHHHHHHHHHHH-T----------TEE????SGGGEEE?-TTS?E-------------------EE???TT?EE?-----------------?????-????????GGG??H----HH----HH--------------T?S???THHHHHHHHHHHHHHHH-----SS------?S??-?S-----SHHHHHHHHHHHH?S??HHHHHHHHT?GGGTT??????SS---------------???HHHH?TT??HHHHHHHHHH??SSTTTS??-----HHHHHTSGGG 3B8R|A PF00070.22_Pyr_redox_seed 130 117 !Q:5,6|18,21|24,24|27,32|35,35|39,39|46,48|52,52|55,55|61,62|67,67|71,74|76,76|80,80|89,94|99,99|101,102|111,114 Q:0,4|7,17|22,23|25,26|33,34|36,38|40,45|49,51|53,54|56,60|63,66|68,70|75,75|77,79|81,88|95,98|100,100|103,110|115,116 EEEEE??SHHHHHHHHHH----HH-HT---?--EE-EEE?SSSSSS---SSS?HH-HHHHH--HHHH-HHT----T?EEE?SEEEEEEE------EETT-E--EEEEEEET----TS 1YQZ|A PF00071.17_Ras_seed 61 229 !Q:4,6|10,10|22,24|26,26|28,31|35,39|42,44|49,58|60,60|70,71|86,86|90,91|97,97|106,106|117,127|130,130|133,134|138,139|141,141|144,176|178,181|190,196|201,204|207,207 Q:0,3|7,9|11,21|25,25|27,27|32,34|40,41|45,48|59,59|61,69|72,85|87,89|92,96|98,105|107,116|128,129|131,132|135,137|140,140|142,143|177,177|182,189|197,200|205,206|208,228 EEEE???TTS?SSHHHHHHHTS???S?S????SEE-----EE???EESS----------S?EEEEEEEEE??SGGGHHHHGGGSTT?SEE??EEETT?HHHHHTHH-HHHHHHHHHS?----------TT?EE??EEE??S?GG---------------------------------G????HHHHHHHH-------HHHT-???EE?BTTTTBTTTHHHHHHHHHTTT 1NVU|Q PF00072.19_Response_reg_seed 57 157 !Q:4,5|7,7|20,24|26,26|29,33|36,36|49,52|55,63|68,78|81,81|84,85|87,90|99,99|102,102|108,112|118,118|120,123|132,132|136,137|145,147 Q:0,3|6,6|8,19|25,25|27,28|34,35|37,48|53,54|64,67|79,80|82,83|86,86|91,98|100,101|103,107|113,117|119,119|124,131|133,135|138,144|148,156 EEEE-?S?HHHHHHHHHHHH-----H-TT?--??EE-EESSHHHHHHHH----HH??-----??EEEE?----------SS?SS--S---?HHHHHHHH-HH?TTTTT---??EEEEE-S???-HHHHHHHH-HTT-?SEEEESS?-?HHHHHHHHH 2CHF|A PF00073.15_Rhv_seed 50 379 !Q:2,2|4,5|11,11|15,47|52,52|55,58|63,63|66,68|76,76|83,86|88,94|112,112|116,135|138,143|147,155|157,166|168,176|178,180|182,184|187,190|194,197|200,200|206,208|213,214|217,220|222,223|225,225|229,234|238,241|243,244|249,254|260,260|262,281|297,297|305,307|314,314|317,359|362,364|376,376 Q:0,1|3,3|6,10|12,14|48,51|53,54|59,62|64,65|69,75|77,82|87,87|95,111|113,115|136,137|144,146|156,156|167,167|177,177|181,181|185,186|191,193|198,199|201,205|209,212|215,216|221,221|224,224|226,228|235,237|242,242|245,248|255,259|261,261|282,296|298,304|308,313|315,316|360,361|365,375|377,378 EE?S??TTEEE-GGG????-------??-???????????---?????TTSS?EE-???EEEE-TT???EEEEETG-GGTTSH----H-------HHHHHHHEEEEEEEEEE-EEE--?--------??------?TT------EEE---------E----------E---------E---E---EE----EET????BS?SSSSS???HHHH??GG----G??B?BSS??????TTS????B??BGGG------TTTTS?G--------------------GGGGGSSEEEEETTT?SEEEEEE???SSSSSB?TT-------------------------------------------TB-??EEEEEEEEEEE-EE 1POV|0 PF00074.15_RnaseA_seed 108 167 !Q:0,2|13,14|17,18|20,20|23,26|29,41|45,45|52,52|54,54|57,57|59,62|64,65|72,72|74,76|90,91|93,94|97,97|99,99|103,103|106,106|115,115|118,119|121,126|130,131|141,141|152,160 Q:3,12|15,16|19,19|21,22|27,28|42,44|46,51|53,53|55,56|58,58|63,63|66,71|73,73|77,89|92,92|95,96|98,98|100,102|104,105|107,114|116,117|120,120|127,129|132,140|142,151|161,166 ???HHHHHHHHHB?-TT--S?SS??--TT-------------HHH-HHHHHT-T?SS-S----S??SEEEEE?S?--HHHHHHGGGSEEE??T--TS?S?EEE?SS?EEEEEEEE?TT-?B------TTB??EEEEEEEEE-EEEEEETTTT---------EEEEEE 1RTB|A PF00075.19_RNase_H_seed 65 246 !Q:0,0|3,3|16,18|23,25|30,30|37,51|58,58|63,67|70,70|74,74|86,86|88,93|95,104|108,112|116,117|121,126|133,133|139,163|165,165|167,170|175,176|178,179|183,184|186,186|189,193|206,206|210,210|216,217|220,220|222,229|231,231|246,246 Q:1,2|4,15|19,22|26,29|31,36|52,57|59,62|68,69|71,73|75,85|87,87|94,94|105,107|113,115|118,120|127,132|134,138|164,164|166,166|171,174|177,177|180,182|185,185|187,188|194,205|207,209|211,215|218,219|221,221|230,230|232,245 ?SS-EEEEEEEEESST---TEEE---EEEE-EEEETT---------------EEEEEE-EEEE-----EE?HHH-HHHHHHHHHHH-T?----?S?--------?EEE-----EEE??HHH------HHHHHT-THHHH-------------------------H-H----TTSB?-T--TSS--B?TT-----HHHHHHHHHHHT-TSE-EEEEE??GG-G??------H-HHHHHHHHHHHHTT- 1REV|A PF00076.17_RRM_1_seed 79 79 !Q:5,8|12,12|23,23|26,28|37,39|53,53|55,55|69,69|72,72|76,76 Q:0,4|9,11|13,22|24,25|29,36|40,52|54,54|56,68|70,71|73,75|77,78 EEEES?--?TTS?HHHHHHHHHT-TS??-SEEEEEEE---TTTTEEEEEEEEE?S?HHHHHHHHHHSSS-BS?SSS?BE 2ERR|A PF00077.15_RVP_seed 50 127 !Q:0,0|4,5|15,26|33,33|36,36|42,42|44,47|49,55|69,69|89,93|99,102|105,111|114,114|123,123 Q:1,3|6,14|27,32|34,35|37,41|43,43|48,48|56,68|70,88|94,98|103,104|112,113|115,122|124,126 ?SSS??EEEEEETTE------------EEEEEE?TT?SSEEE?S????S?------EEEEEEEETTEEE-EEEEEEEEEEEETTEEEEE-----EEEES?--?SS?------EE?HHHHGGGT?EEE 2QD8|A PF00078.22_RVT_1_seed 152 419 !Q:1,18|23,36|45,78|80,80|83,85|89,107|109,111|119,119|128,129|134,134|138,138|142,143|145,195|198,199|201,202|210,211|214,214|236,306|309,309|323,323|325,325|329,338|353,355|358,362|367,408 Q:0,0|19,22|37,44|79,79|81,82|86,88|108,108|112,118|120,127|130,133|135,137|139,141|144,144|196,197|200,200|203,209|212,213|215,235|307,308|310,322|324,324|326,328|339,352|356,357|363,366|409,418 E?????----------???EEEE-------------?THHHHHHB??-----------------------------???S?SS???GGG?------------------B??-SEEEEEE?TTTGGGSB??GGGG-GGG?EEE??G---------------------------------------------------GG?-S??EEEEESB??TT?TTHHHHHHHHHHHHHHHHHHH?----------------------------------------------------------------------TT?EEEEETTEEEEEE?S?HHH----------HHHHHHHHHHHHHH---TT?????GGGS??----------------------------------------SSEEETTEEE 1REV|A PF00079.15_Serpin_seed 180 783 !Q:17,23|27,27|31,31|36,41|52,53|55,56|63,64|69,71|74,112|115,121|123,123|127,150|155,155|161,189|192,192|204,205|207,210|212,213|216,216|218,218|220,220|230,232|236,239|243,243|247,247|264,278|282,285|287,287|291,292|294,294|296,299|310,310|315,319|323,323|327,327|331,332|336,342|344,344|347,347|353,353|357,361|367,372|374,374|384,385|391,414|417,420|424,424|431,440|444,445|449,449|452,453|455,456|460,465|468,469|473,477|481,485|489,489|492,492|497,502|506,508|511,512|514,514|516,517|520,525|528,529|531,532|537,537|542,545|550,550|553,556|561,638|641,643|645,649|660,660|666,725|730,731|733,733|744,767|775,777|780,780|782,782 Q:0,16|24,26|28,30|32,35|42,51|54,54|57,62|65,68|72,73|113,114|122,122|124,126|151,154|156,160|190,191|193,203|206,206|211,211|214,215|217,217|219,219|221,229|233,235|240,242|244,246|248,263|279,281|286,286|288,290|293,293|295,295|300,309|311,314|320,322|324,326|328,330|333,335|343,343|345,346|348,352|354,356|362,366|373,373|375,383|386,390|415,416|421,423|425,430|441,443|446,448|450,451|454,454|457,459|466,467|470,472|478,480|486,488|490,491|493,496|503,505|509,510|513,513|515,515|518,519|526,527|530,530|533,536|538,541|546,549|551,552|557,560|639,640|644,644|650,659|661,665|726,729|732,732|734,743|768,774|778,779|781,781 HHHHHHHHHHHHHHHTT?------SSS?EEE?HHHH------HHHHHHHHTT??H--HHHHHH--HHHT---TS???????????????--------????????????????HH-------H-HHH------------------------HHHH-HHHHT?----------------------------SS?SSEEEEEEEEE--E----E--TT-S?B?HHHHHHHHH---HHS??-?EEE?TTT?HHHHHHHHHHHHHHHT---------------TTS????S?GGG??S-S--??EEEEEEEEEE?BBSS--???GGG?EEE-EEE--SSS-------S?EE-EEEEE-EEE-----EEEEE------E-EETTTTEEE--EEEEB------------------------GG----GSE-EEEEEE----------ESS??SSS-SS-?H--HHH------TT??HHH-----HHH-----HHT?TT?EEEE------EEE---EE--E?E--EE??----EE--E?-HHHH-HHTT--??GGGS-TT??-?TTTB------------------------------------------------------------------------------SS---S?????EEEEEEEEEE?SSBSS???????????-----------------------------------------????????EEEE??S?EEEEEEETTT------------------------TEEEEEE---EE?S? 2VDX|A PF00080.15_Sod_Cu_seed 127 280 !Q:6,26|30,34|45,46|49,54|64,69|71,95|97,98|107,112|116,125|130,130|133,138|141,151|153,154|156,156|159,174|176,176|184,185|188,189|193,193|195,196|200,201|206,206|208,212|219,221|223,223|225,228|230,231|239,241|244,244|246,259|269,270|276,276|279,279 Q:0,5|27,29|35,44|47,48|55,63|70,70|96,96|99,106|113,115|126,129|131,132|139,140|152,152|155,155|157,158|175,175|177,183|186,187|190,192|194,194|197,199|202,205|207,207|213,218|222,222|224,224|229,229|232,238|242,243|245,245|260,268|271,275|277,278 EEEEEB?--------------------SSS----?EEEEEEEEET--TE------EEEEEEEES---?-?S-------------------------E--EEEEEEES????--TTT----------TGGG?SB?----?TT?--??--?-??T--T?SS----------------S?TTEEEEE--EE-?TTS?E--EEE--EEES-S?----BSSSTT---B?T----T-?EEEEESS???TT?S-------------?STTHHHHTT??SEEEE-EE? 1F1G|A PF00081.17_Sod_Fe_N_seed 25 94 !Q:0,6|9,9|18,18|37,37|45,45|52,55|62,62|67,67|78,78|93,93 Q:7,8|10,17|19,36|38,44|46,51|56,61|63,66|68,77|79,92 ???????SS?TTTTTTTS?HHHHHHHHHTHHHHHHHH-HHHHHTT?HHHHTS---?HHHHTT?GGGS?GGGHHHHHHH-HHHHHHHHHHHHTB? 1SZX|A PF00082.17_Peptidase_S8_seed 63 875 !Q:6,6|8,8|10,18|23,60|64,76|78,166|168,171|173,191|203,204|206,210|212,212|218,218|221,221|226,226|228,231|242,247|253,256|265,279|283,287|292,295|299,319|330,332|334,340|343,345|348,349|355,358|360,387|390,391|397,400|403,411|413,418|425,425|431,432|434,439|446,466|474,481|484,486|493,627|630,646|648,652|655,659|662,663|665,673|675,686|689,698|703,703|705,706|709,717|722,724|727,727|729,741|744,746|753,753|758,766|787,805|817,817|819,820|823,850|853,861|865,868 Q:0,5|7,7|9,9|19,22|61,63|77,77|167,167|172,172|192,202|205,205|211,211|213,217|219,220|222,225|227,227|232,241|248,252|257,264|280,282|288,291|296,298|320,329|333,333|341,342|346,347|350,354|359,359|388,389|392,396|401,402|412,412|419,424|426,430|433,433|440,445|467,473|482,483|487,492|628,629|647,647|653,654|660,661|664,664|674,674|687,688|699,702|704,704|707,708|718,721|725,726|728,728|742,743|747,752|754,757|767,786|806,816|818,818|821,822|851,852|862,864|869,874 EEEEEE-S?B------???TTTG--------------------------------------GGB?-----?-----?E-----------------------------------------------------------------------------------------E????H-------------------HHHTSSSSSBS??B?????B?SSTTS?TT?GGGS?B????HHHHHHHHHH???---SSSSS?-??TTTTSEEE---------------EEE?---?BTTB--??HHH---------------------HHHHHHHHTT???T-------TS???SS??SEEEE????B----------------------------SS??HHHHH----HH---------H------HHHHTT?EEEEE??S------SSSBGG---------------------GBTTTTS--------SS?--EEEEEE?--------------------------------------------------------------------------------------------------------------------------------------TT-----------------S-----SB----?TT??B---------S------------TT?--------?EEEE?S--SE---------EEEE---ES?S-------------SS???EEEEEE?SHHH---------HHHHHHHHHHHHHHHHHHTT???---------------?HHHHHHHHHHT?B??SS--------------------------??SS??------?SSB--??HHHHHH 3GCW|A PF00083.19_Sugar_tr_seed 44 605 !Q:9,9|34,34|36,38|42,107|138,138|141,141|147,147|161,161|168,168|175,176|182,182|213,216|221,221|233,233|248,248|253,253|256,257|283,283|287,289|294,294|299,299|302,302|311,313|318,321|343,350|357,358|360,365|381,381|398,399|403,403|413,413|424,424|426,428|435,435|438,444|451,457|470,474|481,492|524,524|541,542|556,556|568,568|589,592|595,596 Q:0,8|10,33|35,35|39,41|108,137|139,140|142,146|148,160|162,167|169,174|177,181|183,212|217,220|222,232|234,247|249,252|254,255|258,282|284,286|290,293|295,298|300,301|303,310|314,317|322,342|351,356|359,359|366,380|382,397|400,402|404,412|414,423|425,425|429,434|436,437|445,450|458,469|475,480|493,523|525,540|543,555|557,567|569,588|593,594|597,604 HHHHHHHHH-HHHHHHHHGGGGTHHHHHHHHTGG-G???HHH------------------------------------------------------------------HHHHHHHHHHTHHHHHHHHHHHHHHHHHHT?HH-HHHHH-HHHHHHHHHHHHH?TTTTTS?SSSSSS??GGGGG?HHHHHHHHHHHHHHHHHHHHHHHHHHHTTS---?GGGH-HHHHHHHHHHH-HHHHHHHHHHHHHH-HTTS?TT--TTTTTHHHHHHHTTHHHHHHHHHHG-GGS???HHHH-HHTT?HH-HHHHHHHH---HHHH----HHHHHHHHHHHHHHHHHHHHT--------THHHHS??T------HHHHHHHHHHHHHHT?HHHHHHHHHHHHHHSS??HHH-HHHHHHHHH-HHHHHHHHHH-H---HHHHHH?SH-------HHHHHH-------HHHHHHHHHHHH-----HHHHTT??----------HHHHHHHHHHHHHHHHTTTTHHHHHHHHHSS?TTTHHHHHHHHHHHHH--HHHHHHHTHHHHH?HHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHH????TT??HHHHGGGT 4GC0|A PF00084.15_Sushi_seed 66 92 !Q:1,12|22,29|33,33|36,36|43,44|54,55|59,59|65,67|69,72|75,75|79,87|89,90 Q:0,0|13,21|30,32|34,35|37,42|45,53|56,58|60,64|68,68|73,74|76,78|88,88|91,91 B?---????----SSTTEEEES??------SSB?TT?EEEEEE-?TTEEEESSS-?EES?EEEEB--?T----TS?BSS?-?----?-E--E 1OK9|A PF00085.15_Thioredoxin_seed 50 123 !Q:0,0|4,5|9,10|18,21|23,25|27,27|34,34|37,37|57,61|63,63|72,72|74,76|85,86|102,103|108,111 Q:1,3|6,8|11,17|22,22|26,26|28,33|35,36|38,56|62,62|64,71|73,73|77,84|87,101|104,107|112,122 ?EEE??TTT--HHHHTTT---?S---S?EEEEEE?TT?HHHHHHHHHHHHHHHHTTT-----T?EEEEEETT-T?--HHHHHHTT??SSSEEEEEETTEEEE--EEES?-??HHHHHHHHHHT 4AJ8|A PF00086.13_Thyroglobulin_1_seed 20 84 !Q:14,16|19,20|24,24|27,29|31,34|36,37|41,41|43,43|55,56|61,61|66,70|72,72|75,76|79,83 Q:0,13|17,18|21,23|25,26|30,30|35,35|38,40|42,42|44,54|57,60|62,65|71,71|73,74|77,78 HHHHHHHHHHHHHH???SS-?SSS?SS???B????B?-TTS?B?SEEEEBSSTTT??EEEE?SSTT?????S?SS??SS--??? 2H7T|A PF00087.16_Toxin_1_seed 48 80 !Q:0,0|4,4|7,8|11,12|16,18|21,22|28,33|36,37|43,43|46,47|49,49|58,62|64,64|66,66|72,72|75,75 Q:1,3|5,6|9,10|13,15|19,20|23,27|34,35|38,42|44,45|48,48|50,57|63,63|65,65|67,71|73,74|76,79 ?EEE?SS--TT??EEE??-TT??EEEEE------EE-?SSTTS-SS??E-EEEEEESS?????S-S?EEEEE-SS-GGGS 1JBD|A PF00088.13_Trefoil_seed 86 73 !Q:3,12|17,21|24,28|34,34|38,38|40,53|55,56|58,64|67,67|71,71 Q:0,2|13,16|22,23|29,33|35,37|39,39|54,54|57,57|65,66|68,70|72,72 GGG-?-------?SSSS?????TT---??TTTHH-HHT?B???-----------S-?T-------TS?SSB?S 3CTT|A PF00089.21_Trypsin_seed 71 348 !Q:0,0|3,3|6,7|11,15|26,35|47,48|52,52|54,54|58,59|61,78|80,80|83,87|91,92|98,99|101,107|115,116|120,120|123,124|128,140|143,144|152,163|168,170|172,173|175,178|180,185|188,188|196,202|206,214|217,217|225,226|229,229|235,237|242,258|266,266|268,273|275,275|277,278|280,281|284,284|287,287|295,302|309,312|315,316|321,321|324,329|333,333|338,341 Q:1,2|4,5|8,10|16,25|36,46|49,51|53,53|55,57|60,60|79,79|81,82|88,90|93,97|100,100|108,114|117,119|121,122|125,127|141,142|145,151|164,167|171,171|174,174|179,179|186,187|189,195|203,205|215,216|218,224|227,228|230,234|238,241|259,265|267,267|274,274|276,276|279,279|282,283|285,286|288,294|303,308|313,314|317,320|322,323|330,332|334,337|342,347 ?BT?EE??TTS?----TTEEEEESSS----------EEEEEEEEETT--EEE-E?GGG??S------------------S?EE-----EES?-SBSSS??S?-----?EEEEEEE--EEE?TT??TTT-?-----------TT??EEEEESS?--------???SSSS???B??S----S??---?TT?EEEEEES??---??SSS?-----???SB?EEEEEEB??HH-HHHHH---STTT---------------??TTEEEES?T------T?S-?B??TT?TT?EEEETTE--------EEEEEE----EE--SSSS?TT?----?EEE-EEGG----GGHHHH 3T26|A PF00090.14_TSP_1_seed 31 60 !Q:0,8|10,11|15,15|18,19|23,24|26,26|29,31|34,38|40,40|44,49|51,52|54,54|56,56|58,59 Q:9,9|12,14|16,17|20,22|25,25|27,28|32,33|39,39|41,43|50,50|53,53|55,55|57,57 ?????????S?-SSS-EE??EEE??S?TT???TT?????S?SEE------E??E-E?S?? 2BBX|A PF00091.20_Tubulin_seed 94 404 !Q:0,0|27,28|32,71|75,77|83,99|103,103|106,106|122,122|130,132|136,136|143,143|145,145|147,150|153,153|156,156|163,190|203,203|208,214|217,219|221,221|223,225|254,284|287,296|305,306|308,310|313,316|331,331|335,335|349,356|359,372|377,378|380,397|399,400 Q:1,26|29,31|72,74|78,82|100,102|104,105|107,121|123,129|133,135|137,142|144,144|146,146|151,152|154,155|157,162|191,202|204,207|215,216|220,220|222,222|226,253|285,286|297,304|307,307|311,312|317,330|332,334|336,348|357,358|373,376|379,379|398,398|401,403 ?EEEEEEHHHHHHHHHHHHHHHHHHHT??TTS------------------------????-?--????????GGG---GTEEE----------------?TTS?EE-ESEEEEESSSHHHHH-HHHSTTT---TTS?GGGEEE?S-S?--?TT?HH-HHHHTS----------------------------HHHHHHHHHHHH-HHHH-------HT?--S-S-??EEEEEEESSSHHHHHHHHHHHHHHHHHT-------------------------------TT--------?-EEEEEEEE??T---TT?-??TTHHHHHHHHHHHH-GGG?SEEEEEEHHHHHH--------HH--------------HHHH??S------------------S??HHH 1W5E|A PF00092.23_VWA_seed 189 295 !Q:7,7|11,25|29,29|40,40|43,52|57,58|70,81|85,85|89,92|102,112|115,120|123,124|128,128|141,150|154,155|157,159|171,175|177,178|195,210|220,220|224,242|254,254|257,257|260,261|275,288|295,295 Q:0,6|8,10|26,28|30,39|41,42|53,56|59,69|82,84|86,88|93,101|113,114|121,122|125,127|129,140|151,153|156,156|160,170|176,176|179,194|211,219|221,223|243,253|255,256|258,259|262,274|289,294 EEEEEEE?STT???------------HHH-HHHHHHHHHT-TS-?-------?STTS??EEEEEESSSEE------------EEE?TTT?--?SHHHHHHHH-----------TT??????SS??HHH-HHHHHHHTTSSG----------GGT??T---TSEEEEEEEES-----S??TTGGGHHHHHHHHHTT----------------TEEEEEEEE?GGG?------------??????HHHHHHHHTTS?SS-GG--GTEEEESSTTGGG--------------GGHHHH- 1ZON|A PF00093.13_VWC_seed 20 99 !Q:2,2|6,6|9,9|12,12|15,15|17,17|19,26|29,29|36,43|51,55|57,63|66,66|68,88|91,91|93,96|98,98 Q:0,1|3,5|7,8|10,11|13,14|16,16|18,18|27,28|30,35|44,50|56,56|64,65|67,67|89,90|92,92|97,97 EE-SSS?EE?SS?EE?S?S--------SE-EEEEET--------TEEEEEE??--?S?-----?SS?S??----------------???SS?S??--S? 1U5M|A PF00095.16_WAP_seed 72 73 !Q:0,0|4,20|22,22|26,26|28,28|30,32|34,35|44,44|46,46|50,55|57,58|60,60|62,62|64,64|68,68|71,72 Q:1,3|21,21|23,25|27,27|29,29|33,33|36,43|45,45|47,49|56,56|59,59|61,61|63,63|65,67|69,70 ?SSB?-?------------??S?EES?S-S???S?-SSGGGSST-T?EEE------E--E-T-T-EEE-EE?? 1UDK|A PF00096.21_zf-C2H2_seed 194 32 !Q:2,2|4,6|9,13|28,30 Q:0,1|3,3|7,8|14,27|31,31 EE?T---TT?---?EESSHHHHHHHTHH---H 1XRZ|A PF00097.20_zf-C3HC4_seed 35 66 !Q:0,0|3,4|6,8|10,10|12,26|35,35|47,55|58,58|60,61 Q:1,2|5,5|9,9|11,11|27,34|36,46|56,57|59,59|62,65 ?SS??S???S?E---------------EETTTTEE-ESTTHHHHHHH---------HS?S--TTTT 2DJB|A PF00098.18_zf-CCHC_seed 184 18 !Q:0,0|2,2|6,7|11,11|15,17 Q:1,1|3,5|8,10|12,14 ?B?TTT??BSS?GGG??? 1ESK|A PF00100.18_Zona_pellucida_seed 143 550 !Q:2,2|4,4|8,16|23,24|26,26|29,46|53,59|64,74|76,77|79,89|106,115|118,118|120,120|124,133|137,138|143,144|150,154|157,179|186,189|195,195|200,223|225,272|274,274|277,301|308,334|341,364|366,367|369,369|372,372|376,376|382,383|387,399|403,410|418,419|423,424|426,426|429,429|438,438|452,454|457,467|470,470|480,480|483,484|489,512|515,515|530,533|538,545 Q:0,1|3,3|5,7|17,22|25,25|27,28|47,52|60,63|75,75|78,78|90,105|116,117|119,119|121,123|134,136|139,142|145,149|155,156|180,185|190,194|196,199|224,224|273,273|275,276|302,307|335,340|365,365|368,368|370,371|373,375|377,381|384,386|400,402|411,417|420,422|425,425|427,428|430,437|439,451|455,456|468,469|471,479|481,482|485,488|513,514|516,529|534,537|546,549 EE?S-SEE---------EEEEES??S?SS--------------????GGGEEE-------TTTT-----------B??S-----------EEETTTTEEEEEEETT?---------TT?E-EEE---------?SSE--EEEE--EEEEE?????SS-----------------------TTEESS??--EEEEE-EEEE------------------------E?????-???----------------------------------?????B?TT????----?-??????---------EEEEEE?--------------------------TTSSSB----------------------??S??B?TT?EEE-EEEEE??TTB??-----------EEE--------EEEEEEE--ESS--S?TT-SSSEEEEE-BTTTEEGGGGSTT???EE----------?SS?SSTTEEEEE-EE??EETT?-----------------------SS?EEEEEEEEEEEETT?-??BTTB??------EEEE 3NK4|A PF00101.15_RuBisCO_small_seed 48 119 !Q:0,1|9,11|27,27|37,38|40,46|48,48|51,52|56,57|60,62|67,69|72,74|89,89|104,105|116,117 Q:2,8|12,26|28,36|39,39|47,47|49,50|53,55|58,59|63,66|70,71|75,88|90,103|106,115|118,118 ??STTTTSS???HHHHHHHHHHHHHTT?EEEEEEESS??S?------B?SS??STT??BS???EEES???TT???HHHHHHHHHHHHHH?TTSEEEEEEEETTT--TEEEEEEEEE??T 1WDD|S PF00102.22_Y_phosphatase_seed 114 462 !Q:4,4|10,12|15,16|19,56|59,59|62,67|73,91|96,96|98,100|108,134|136,136|140,142|153,154|156,158|163,163|165,165|170,178|181,185|187,187|189,191|193,202|205,206|213,213|220,226|230,230|232,232|244,248|250,253|256,288|292,292|298,303|305,307|311,317|319,321|323,328|334,337|348,364|368,369|374,374|376,380|402,408|412,414|416,416|420,427|434,434|442,442|444,448 Q:0,3|5,9|13,14|17,18|57,58|60,61|68,72|92,95|97,97|101,107|135,135|137,139|143,152|155,155|159,162|164,164|166,169|179,180|186,186|188,188|192,192|203,204|207,212|214,219|227,229|231,231|233,243|249,249|254,255|289,291|293,297|304,304|308,310|318,318|322,322|329,333|338,347|365,367|370,373|375,375|381,401|409,411|415,415|417,419|428,433|435,441|443,443|449,461 GGGG?SSTTS???GG--GB????-----------------------------?????GG-GG--?--?SEEEE-------------------EETT-E---EEEEEEE???-------?----------------G-GGH---HHHHHHHHHH--T-??EEEE?S?SEET---------TE-----E?S???S?---------SS--EEEETT-EEEEEE-------EEE-E?SSEEEEEEEEE-----E----TT??-----------------------------??EEE-EEEEE?----?S?--SSS-------S?--S?-----SHHHH----HHHHHHHHHS----------------?TTS??EEEE?S-----SSSHHHHHHHHHHHHHHHHHH-------HSE---E?HHH--------HHHHHH-HHSTTSS?S-----HHHHHHHHHHHHH 1I9T|A PF00103.15_Hormone_1_seed 17 237 !Q:0,15|18,19|21,21|23,26|29,32|63,89|95,98|107,107|138,142|171,187|191,195|230,236 Q:16,17|20,20|22,22|27,28|33,62|90,94|99,106|108,137|143,170|188,190|196,229 ---------??----?TT??S?S----SS????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??????---------??----??????GGGSS????SSTTTTTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHTTS??--?SSHHHHHHHHHHHHHHHHHHHHHHHHHS?--??????????????TTT?????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTT????--? 1F6F|A PF00104.25_Hormone_recep_seed 86 353 !Q:0,20|28,28|35,37|48,48|54,54|57,58|64,64|85,95|103,103|107,107|118,139|141,141|148,158|166,166|172,172|174,179|193,193|195,199|201,201|204,204|206,213|217,220|237,248|252,252|255,275|283,284|293,304|307,320|328,345|350,351 Q:21,27|29,34|38,47|49,53|55,56|59,63|65,84|96,102|104,106|108,117|140,140|142,147|159,165|167,171|173,173|180,192|194,194|200,200|202,203|205,205|214,216|221,236|249,251|253,254|276,282|285,292|305,306|321,327|346,349|352,352 ????-???????----?????SHHHHHH-HHHHHH---HHTHHHHHHT-STTTT-TS-?HHHHH-HHHHHHHHHHHHHHHHHHTS-----------SSSSEEE?TTS?EEEHHHHHHT----------------------T?HHHHHH-----------HHHHTHH-HHHHT-T?----?HHHHHHHHHHHHS?T-----T?TT?S-------?HHH----HHHHHHHHHHHHHHHH------------HHH?TT?--------------------TTHHHHH--HTHHHHHH------------HH--------------HHHHHTT------------------TTTS??G 1Q4X|A PF00105.13_zf-C4_seed 26 74 !Q:0,2|6,6|8,10|18,19|34,40|43,43|45,50|58,58|71,72 Q:3,5|7,7|11,17|20,33|41,42|44,44|51,57|59,70|73,73 ???TTT?S???SEETTEE??HHHHHHHHHHHHTT??--???SS?S?--???STTTGGG?HHHHHHHHHHTT??G 1KB6|A PF00106.20_adh_short_seed 230 225 !Q:7,7|23,23|25,25|35,47|58,62|68,70|74,76|83,88|91,91|93,93|103,107|111,111|118,127|129,131|135,141|147,148|155,158|172,175|177,184|199,199|202,202|224,224 Q:0,6|8,22|24,24|26,34|48,57|63,67|71,73|77,82|89,90|92,92|94,102|108,110|112,117|128,128|132,134|142,146|149,154|159,171|176,176|185,198|200,201|203,223 SEEEEET?SSHHHHHHHHHHHHT-T?SEEEEEESS-------------GGGSTTHHHH-----HHHHH---HTT--?EEEEEE-??---TT?H-HHHHHHHHT??---TTS?EEEEEE????---??-S???TTT?-----?HHHHH--HHHHTT----HHHHHHHHHHHTT----S?------?SEEEEEEEHHHHTT?TT?HHHHHHHHHHHHHHHHHHHTT? 1NXQ|A PF00107.21_ADH_zinc_N_seed 108 188 !Q:14,21|29,29|41,44|46,46|53,56|59,61|86,86|88,94|96,97|104,104|106,107|128,129|132,143|145,149|158,158|163,164|166,174 Q:0,13|22,28|30,40|45,45|47,52|57,58|62,85|87,87|95,95|98,103|105,105|108,127|130,131|144,144|150,157|159,162|165,165|175,187 TTHHHHHHHHHTTT-------?EEEEEES?TTHHHHHHTTT---?S?EEEGGG????SS???TTSHHHHHHHHHHHHHHHHHHHHH?T-------T??EEEEEE?S?-TTTHHHHHHHEEEEEEEEES??TT-----------?S?????HHHHHHTT?EEEE??S??-------HHHHHHHHHHHHT 3QWA|A PF00108.18_Thiolase_N_seed 22 291 !Q:0,2|11,13|15,15|24,25|43,46|49,50|52,53|59,59|61,62|66,67|69,69|80,81|91,91|112,112|114,114|126,127|131,135|138,140|143,144|153,166|172,172|176,177|192,193|222,223|227,230|233,237|241,241|243,243|246,247|250,251|258,259|263,263|266,269|275,277 Q:3,10|14,14|16,23|26,42|47,48|51,51|54,58|60,60|63,65|68,68|70,79|82,90|92,111|113,113|115,125|128,130|136,137|141,142|145,152|167,171|173,175|178,191|194,221|224,226|231,232|238,240|242,242|244,245|248,249|252,257|260,262|264,265|270,274|278,290 ???EEEEEEEE???E-ETTSTTTT??HHHHHHHHHHHHHHHHT--??GG--G??EEEEE?S??TTS-?S?HHHHHHHHTT??TTSEEEEEE?GGGHHHHHHHHHHHHHHTTS?S?EEEEEEEETTT??EEE---??SS???SS-?EEEEEHHH--------------HHHTB?TTT??BHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHHHHHHTTTTTTB??EEE??--TT??---EEE?S?TT??TT??HHHHHT??BSS?TT-???BTTSB???EEEEEEEEEEEHH 2WL4|A PF00109.21_ketoacyl-synt_seed 167 348 !Q:0,2|12,12|16,25|38,41|43,51|53,54|58,60|66,69|71,71|77,77|80,81|85,86|88,92|97,97|103,104|112,112|118,118|132,134|139,141|145,157|163,178|180,186|189,192|194,203|206,206|209,210|215,221|233,235|239,239|241,241|247,247|253,253|269,269|279,280|287,287|295,297|299,299|302,312|318,329|331,331|334,334 Q:3,11|13,15|26,37|42,42|52,52|55,57|61,65|70,70|72,76|78,79|82,84|87,87|93,96|98,102|105,111|113,117|119,131|135,138|142,144|158,162|179,179|187,188|193,193|204,205|207,208|211,214|222,232|236,238|240,240|242,246|248,252|254,268|270,278|281,286|288,294|298,298|300,301|313,317|330,330|332,333|335,347 ???EEEEEEEEE?STT??--------SHHHHHHHHHTT????E---------E??SSS???HHHHB---?S?TTSTT?BS??EEB??S----?SSEE?HHHHT??HHHHHTS?HHHHH-HHHHHHHHHHHTT?-?GGGG---TTB?-----------?EEEEE????-----------?T-------TT----T????---??-TT?HH--HHTT------?HHHHHHHHHHH---HTB?S?EEEEE?GGGHH-HHHHHHHHHHHHTTS?SSEEEEEEE??SSTHHH-HHHHTTT--?B?SS---??----??TTBTT?---------??B?BB?EEEEEEEEEHHHH 1F91|A PF00110.14_wnt_seed 104 621 !Q:0,21|26,29|57,61|63,63|65,97|102,102|105,106|108,111|138,139|142,146|149,168|177,245|249,249|251,254|256,256|271,280|288,289|306,306|313,316|321,321|327,346|350,350|352,354|369,370|373,480|485,494|501,501|505,505|508,508|510,513|522,522|526,526|530,530|533,549|552,558|565,565|575,576|587,587|589,589|591,591|593,600|604,605|607,608|620,620 Q:22,25|30,56|62,62|64,64|98,101|103,104|107,107|112,137|140,141|147,148|169,176|246,248|250,250|255,255|257,270|281,287|290,305|307,312|317,320|322,326|347,349|351,351|355,368|371,372|481,484|495,500|502,504|506,507|509,509|514,521|523,525|527,529|531,532|550,551|559,564|566,574|577,586|588,588|590,590|592,592|601,603|606,606|609,619 -------------?????????HHHH----HHHHHHHHHHHHHHHHHHHHHTTTSSS?????T-T---------------------------------HHHH?TT??S?--?HHHHHHHHHHHHHHHHHHHHHHHTTT?-SS?????TT--------------------TTSEEETT---------------------------------------------------------------------EEE?S????H-HHHHHHHHHHHHHH?--------?SSSHHHH--HHHHHHHHHHHHHHHT?EEEEEE?---SGGG?TTSEE--------------------EEE-E???HHHHHHHHHHHHHT-?EE???????????????-------------------------------------------------------------------------------------------??HHHH----------HHHHTS?SSS?EE?S????TTSEETTT-TEE?STT?EE-------------????TT??-----HHHHTH-HHHHTGGGT??EEEEEEEEEE-E?S?B-??-----SSS??B??EEEEEEEEEEE? 4F0A|B PF00111.22_Fer2_seed 206 124 !Q:1,1|5,9|14,14|18,19|26,28|30,30|32,32|34,38|43,49|52,57|60,62|69,75|78,81|84,85|93,116|120,121 Q:0,0|2,4|10,13|15,17|20,25|29,29|31,31|33,33|39,42|50,51|58,59|63,68|76,77|82,83|86,92|117,119|122,123 E?TTS?--??EEEE?TTS?-HHHHHH---H-H-T?????SSSS-------SS----??SS???EEEEEE-----??SS---?SS??HHHHHHT??---------------------?GGG??EE 3NA1|C PF00112.18_Peptidase_C1_seed 157 367 !Q:0,1|3,3|9,10|13,21|23,27|31,31|51,59|61,61|69,72|75,86|90,91|93,93|104,106|109,109|111,112|118,132|135,163|166,166|170,176|178,180|185,188|191,198|209,210|212,212|214,214|219,221|224,226|231,232|235,244|247,264|275,275|277,312|315,315|322,322|325,326|332,332|340,343|345,345|348,349|352,352|356,357|362,362 Q:2,2|4,8|11,12|22,22|28,30|32,50|60,60|62,68|73,74|87,89|92,92|94,103|107,108|110,110|113,117|133,134|164,165|167,169|177,177|181,184|189,190|199,208|211,211|213,213|215,218|222,223|227,230|233,234|245,246|265,274|276,276|313,314|316,321|323,324|327,331|333,339|344,344|346,347|350,351|353,355|358,361|363,366 ??S?EETTT--TT-?--?????B??---SSB?HHHHHHHHHHHHHHHHHHS-----????B?HHHHHHH??--SS??----------TTB?-B?HHHHHHHHHH---HT?B?-BTTTS-------???-----SS?------------------------????HH-HHT??----?B???EEEE--??TT-------?HHHHHHHHHH--S?E-EEEE???SH---HHHT??SS----------EE??---???------????EEEEEEEEEE?T------------------------------------TS?EEEEEE?SB?-TTSTB-TTEEEEE?---S?SS--TT?GGG--TTSS?EEEE 2YJ8|A PF00113.17_Enolase_C_seed 11 298 !Q:0,2|4,4|13,13|21,22|24,24|30,30|33,33|59,59|63,64|66,66|70,70|72,77|94,94|97,98|100,100|106,107|113,114|120,120|126,126|128,129|133,133|135,135|151,151|157,158|160,160|163,163|175,177|189,189|201,202|208,208|213,214|230,230|236,237|240,241|243,244|255,255|260,262|264,264|286,287|289,289|295,295|297,297 Q:3,3|5,12|14,20|23,23|25,29|31,32|34,58|60,62|65,65|67,69|71,71|78,93|95,96|99,99|101,105|108,112|115,119|121,125|127,127|130,132|134,134|136,150|152,156|159,159|161,162|164,174|178,188|190,200|203,207|209,212|215,229|231,235|238,239|242,242|245,254|256,259|263,263|265,285|288,288|290,294|296,296 ???B?EEEEEEEE?GGGSSSS??S?EEEEE?TT?SSHHHHHHHHHHHHHHHHHHHHHHH?GGG??B?TTS?B??????HHHHHHHHHHHHHHTT?TT--T?EEEEE??GGGTE--ETTEE?TTTTS-S??GGG?B?HHHHHHHHHHHHHHS?EEEEE??S?TT?HHHHHHHHHHH?--SEEEESTTTTT?HHHHHHHHHHT??SEEEE?HHHH??HHHHHHHHHHHHHTT?EEEEE??SB??S??HHHHHHHHTT?SEEE???S?SHHHHHHHHHHHHHHHHHGGG??B?GGGTT?S? 3OTR|A PF00114.14_Pilin_seed 147 217 !Q:26,33|36,38|43,55|59,59|65,66|68,73|84,106|114,114|119,119|121,124|129,129|137,138|141,167|178,178|187,192|196,197|200,200|202,204|209,211|213,213|216,216 Q:0,25|34,35|39,42|56,58|60,64|67,67|74,83|107,113|115,118|120,120|125,128|130,136|139,140|168,177|179,186|193,195|198,199|201,201|205,208|212,212|214,215 HHHHHHHHHHHHHHTHHHHHHHHHHH--------SS???SHHH-------------HTS?SSGGG--S??----SSEEEEEEET-----------------------TEEEEEE?SSSS?G----GGTT?EEEEEEE--EE---------------------------TTEEEEEEES?EEEEETTE------EEE??SS?B?-?GGGS?--T-TS? 2PY0|A PF00115.15_COX1_seed 94 591 !Q:3,3|31,32|36,53|55,55|57,59|62,62|64,66|104,104|107,107|114,114|133,138|143,159|161,161|164,165|167,167|171,171|176,180|182,188|217,218|224,224|227,228|233,234|237,237|253,253|270,272|275,275|280,281|304,304|319,319|322,322|334,334|341,341|344,344|349,349|352,352|354,356|372,381|388,398|406,411|415,429|443,443|491,494|503,510|535,535|540,540|542,542|546,550|553,560|563,569|574,577|585,586 Q:0,2|4,30|33,35|54,54|56,56|60,61|63,63|67,103|105,106|108,113|115,132|139,142|160,160|162,163|166,166|168,170|172,175|181,181|189,216|219,223|225,226|229,232|235,236|238,252|254,269|273,274|276,279|282,303|305,318|320,321|323,333|335,340|342,343|345,348|350,351|353,353|357,371|382,387|399,405|412,414|430,442|444,490|495,502|511,534|536,539|541,541|543,545|551,552|561,562|570,573|578,584|587,590 HHH-HHHHHHHHHHHHHHHHHHHHHHHHHHT--SSS------------------S?S---SS?H---HHHHHHHHHHHHHHHHTTHHHHHTTTHHHHHHHHHTT?SS?SSHHHH-HHHHHTHHHHHHHHHHHH------HSTT??--------------?S?TT??T-TTT-STTT-----T?------SSHHHHHHHHHHHHHHHHHHHHHHHHHH--HHHSS?TT??GGGS-?HH-HHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHS???SS?GGGT??HHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHTT?SS?TTHHHHHHHHH-HHHHHT-TS?GGGG?TT-S???HHHHHHHHHHHHHTH----------HHHHHH-----------HHHHHHH------HTT?----?----????-HHHHHHHHHHHHH-HHHHHHHHHHHSHHHHHHHTTBHHHHHHHHHHTHHHHHHHHHHHHHH----HHHHHHSB-----???HHHHHHHHHHHHHHHHHHHTHHHH-HHHT-T?BSS?----SS?------?GG-------GHHH----HHHHHHH--HHHH 1V55|A PF00116.15_COX2_seed 32 136 !Q:16,16|20,25|31,31|33,34|38,39|42,43|45,48|51,51|55,55|63,63|71,74|78,78|93,93|96,97|103,107|110,110|116,118|120,121|128,129 Q:0,15|17,19|26,30|32,32|35,37|40,41|44,44|49,50|52,54|56,62|64,70|75,77|79,92|94,95|98,102|108,109|111,115|119,119|122,127|130,135 EEEEEEEETTEEEEEE?SSS?-----EEEEE?B??GGG??TT??T----TT?BSS?EEEETTS?EEEEEEE----SSS?EEEEEGGGTEEEEE?TT??EEEEE??---SS?EEEEE???S??STTGGG??EEEEEE 2LLN|A PF00117.23_GATase_seed 134 304 !Q:1,1|21,26|37,41|48,57|61,66|70,70|76,79|84,91|105,108|111,112|133,134|137,141|146,146|149,149|151,152|156,156|160,174|177,192|202,205|208,208|217,217|227,228|231,231|243,245|251,251|255,263|269,269|272,273|283,283|288,289|293,294 Q:0,0|2,20|27,36|42,47|58,60|67,69|71,75|80,83|92,104|109,110|113,132|135,136|142,145|147,148|150,150|153,155|157,159|175,176|193,201|206,207|209,216|218,226|229,230|232,242|246,250|252,254|264,268|270,271|274,282|284,287|290,292|295,303 T?GGGGHHHHHHHHHHHHHHT------EEEEEEEEEH-----HHHHHH?---------TTT------TSS?SEEEE????SSTT--------HHHHHHHHHHHHH----TT??EEEETHHHHHHHHHHHHHTT??TT??---BTTT?TT?S??SEE?TTT??------------?SS????????????????EEEEEEEEE?---TT?HHHHHHTS-SEEEEEEEE??EE?HHHHHHHHHHH--?EEEEE?STT-------??EEEEE?TT--SSSEEEESS?GGGT??TTT??HHHHHHHHH 1WL8|A PF00118.19_Cpn60_TCP1_seed 94 816 !Q:2,7|14,14|18,25|31,33|37,37|42,43|52,55|59,62|72,72|76,76|100,102|105,105|107,108|128,133|137,137|140,142|144,157|172,175|177,178|193,193|197,197|201,220|226,227|231,234|240,242|244,244|246,247|250,250|254,255|260,260|262,263|265,267|269,269|271,277|280,288|292,294|298,298|304,304|306,306|309,315|318,322|327,327|355,357|359,375|377,382|387,387|389,394|406,406|410,410|412,425|437,440|446,458|461,463|465,465|468,474|481,481|489,490|496,496|499,546|549,566|568,568|571,571|577,578|604,605|607,607|609,610|627,628|630,635|641,652|654,654|657,665|669,672|695,696|698,707|714,714|718,721|724,731|735,748|760,765|768,768|770,770|776,782|802,802|807,808|811,815 Q:0,1|8,13|15,17|26,30|34,36|38,41|44,51|56,58|63,71|73,75|77,99|103,104|106,106|109,127|134,136|138,139|143,143|158,171|176,176|179,192|194,196|198,200|221,225|228,230|235,239|243,243|245,245|248,249|251,253|256,259|261,261|264,264|268,268|270,270|278,279|289,291|295,297|299,303|305,305|307,308|316,317|323,326|328,354|358,358|376,376|383,386|388,388|395,405|407,409|411,411|426,436|441,445|459,460|464,464|466,467|475,480|482,488|491,495|497,498|547,548|567,567|569,570|572,576|579,603|606,606|608,608|611,626|629,629|636,640|653,653|655,656|666,668|673,694|697,697|708,713|715,717|722,723|732,734|749,759|766,767|769,769|771,775|783,801|803,806|809,810 HH------HHHHTT?STT??------EEEEE?--SSS?EEEE??HHHHHHHS??-?SHH----HHHHHGGGG?TTT?STTHHHHHHHHHHHHHHHHHHHH---HH-T??HHHHHHHHHHHHHHHHHHH------HHH?EE???H--------------HHHHHHHHHHTTTS----S??STHHHHHHHHHHHH-HHH?EES--------------------SSSEE??GGG----EEEEE???S?S--TT?EEE--SEEE-E--S???S?T-------TS-------?-SEE---EEE-EEEEE?S?BS??-??--SS-?--?EEEE?STTHHHHHHHHHHHHHHHHHHHHHHTT-??E-----------------E------EESS?B-----?HHHHHHHHHHT?EEE?S?------------?HHHHHHHHHHH???-EESSG-------------GG??-G-GG------?EEEEEE-EEEEETT--EEEEE-EE------------------------------------------------EE------------------S?SS?EEEEE??SSSTTHHHHHHHHHHHHHHHHHHHH--H?E--EEETTTHHHHHHHHHH--H------HHHHT------------S?HH---------HHH----HHHHHHHHHTHHHHHHHHHHTS-?H----------HHHHHH-HHH----HH--------HTT?-------------TTEEEETTTTE------EE-E-HHHHT------?EEEHHHHHHHHHHHHHHHH-HHHT??EE????? 1Q2V|A PF00119.15_ATP-synt_A_seed 30 260 !Q:0,58|61,64|86,86|96,100|135,167|195,214|220,220|225,229|257,259 Q:59,60|65,85|87,95|101,134|168,194|215,219|221,224|230,256 ---------------------------------------------------------??HH----HHHHHHHHHHHHHHHHHHHHH-HHHHHHTTS?????SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS??????????????????????????-??????TTHHHHHHHHHHHHHHHHHHHHHHHHH--------------------HHSSS?HHHH-----HHHHHHHHHHHHHHHHHHHHHHHHHHH??? 1C17|M PF00120.19_Gln-synt_C_seed 95 336 !Q:1,2|6,6|18,18|20,20|22,22|31,31|39,42|46,48|53,54|63,63|65,65|72,77|80,87|90,91|95,95|98,99|102,102|104,104|116,116|121,123|130,130|132,132|142,146|170,170|174,175|177,177|183,189|197,200|204,204|206,206|209,209|212,212|214,215|219,220|243,249|259,268|272,273|278,278|281,281|288,297|303,304|309,311|313,320|323,323 Q:0,0|3,5|7,17|19,19|21,21|23,30|32,38|43,45|49,52|55,62|64,64|66,71|78,79|88,89|92,94|96,97|100,101|103,103|105,115|117,120|124,129|131,131|133,141|147,169|171,173|176,176|178,182|190,196|201,203|205,205|207,208|210,211|213,213|216,218|221,242|250,258|269,271|274,277|279,280|282,287|298,302|305,308|312,312|321,322|324,335 T??HHH-HHHHHHHHHHT-T?S?SEEEEEEE?EEEEESE----EEE---EEET--TEEEEEEE?S?TGGGSS---???SS????????SS??SSB?GG--GS-S?STHHHHHHHHH-HHHT?-?EEEEEE?S?TTTEEEEEE?-???HHHHHHHHHHHHHHHHHHHHHHT?EEE??S?SSSSS?--????EEEEEEE----SSS-S?TT?SS-S--SSS??HHHHHHHHHHHHHHHHHHHHSS?------TTTHHHHSS?--------?SSS??EEEE?SS?TTEEEE????------SSGGG??EEEE???T--------TS?HHHHHHHHHHHH 2GLS|A PF00121.13_TIM_seed 56 283 !Q:0,0|6,7|9,14|25,25|33,38|42,44|49,50|57,57|64,70|76,77|82,84|88,88|90,90|93,93|96,98|107,108|114,114|122,127|143,143|147,147|151,153|157,159|164,164|180,181|184,184|186,186|189,192|194,194|199,200|207,207|209,212|232,234|249,250|263,264|275,275 Q:1,5|8,8|15,24|26,32|39,41|45,48|51,56|58,63|71,75|78,81|85,87|89,89|91,92|94,95|99,106|109,113|115,121|128,142|144,146|148,150|154,156|160,163|165,179|182,183|185,185|187,188|193,193|195,198|201,206|208,208|213,231|235,248|251,262|265,274|276,282 ?EEEEE??B??---?HHHHHHHHHH-HHHHTSS----??SSE---EEEE??GGGHHH-HHHHHT-------TSSSE--EEES???SSS-S-BS?TT???HHHHHTTT??EEEES?HHHHHTS?---??HHHHHHHHHHHHHTT?EEE-EEE???HHH---HHHT?HHHHHHHHHHHHHTT??HH-H-HT----T?EEEE??GGGSSS-S????HHHHHHHHHHHHHHHHHHS--?HHHHHHSEEEEESS??HHHHTTTSSSTT??EEEESGGGTS-THHHHHH 3PF3|A PF00122.15_E1-E2_ATPase_seed 126 540 !Q:19,21|27,29|34,34|36,36|38,38|45,71|73,83|88,102|104,104|109,110|113,113|118,119|122,122|124,125|132,172|174,188|193,193|198,199|201,207|209,209|213,255|258,258|261,266|269,269|272,275|278,280|282,287|294,294|308,310|314,316|318,355|373,373|379,401|405,407|411,411|413,482|486,486|489,490|496,496|505,505|528,528|532,532 Q:0,18|22,26|30,33|35,35|37,37|39,44|72,72|84,87|103,103|105,108|111,112|114,117|120,121|123,123|126,131|173,173|189,192|194,197|200,200|208,208|210,212|256,257|259,260|267,268|270,271|276,277|281,281|288,293|295,307|311,313|317,317|356,372|374,378|402,404|408,410|412,412|483,485|487,488|491,495|497,504|506,527|529,531|533,539 HHHHHHHHHHHHHHHHHTT???TTHHH---HHTS?S-E-EEEEET---------------------------T-----------EEEE---------------E-EGGG??TT?EEEE-?TT?B??SEEEEE-----------------------------------------E---?----------?EEEE?HHHH??S-------S?EEE?------------------------------------------TT?EE-----?TT?EE?---SS--?E------EEEEEE?GGGSHHHHHHHHH---SSS??-S?------------------------------------?HHHHHHHHHHHHHHHHH-HHHHH-----------------------HHH---TTS?S----------------------------------------------------------------------STT?TT??SHHHH-HHHHHHHS?TTHHHHHHHHHHHHHHHHHTTT?EES-STTHHHH 3W5C|A PF00123.15_Hormone_2_seed 56 28 !Q:0,0|2,22|26,27 Q:1,1|23,25 ?B?????????????????????EES?? 1BH0|A PF00124.14_Photo_RC_seed 55 317 !Q:0,3|11,12|31,38|41,41|52,53|55,58|65,68|72,84|115,116|143,143|148,149|151,151|168,168|172,172|204,204|207,207|215,216|224,231|239,242|244,247|274,291|296,300|302,302|312,312|314,316 Q:4,10|13,30|39,40|42,51|54,54|59,64|69,71|85,114|117,142|144,147|150,150|152,167|169,171|173,203|205,206|208,214|217,223|232,238|243,243|248,273|292,295|301,301|303,311|313,313 ????HHHHHHH--HHHHHHHHHHHHHHHHTT--------TT?HHHHHHHGGG??B????GGGTTS-???GGG-------------THHHHHHHHHHHHHHHHHHHHHHHHHHTTS??THHHHHHHHHHHHHHHHHTHHHHHHT?GGGS??B?TTHHHHHHHHHHHHTT?GGG?HHHHHHHHHHHHHHHHHHHHHHHHHHTTTTT-TT?HHHHHHS??HHHHHHH--------HHHHHHH----S????TTHHHHHHHHHHHHHHHHHHHHHHTB------------------TTTB-----S?HHHHHHHTT?S??? 3G7F|L PF00125.19_Histone_seed 64 84 !Q:0,1|3,4|6,6|25,31|34,34|58,58|66,66|69,70|72,72 Q:2,2|5,5|7,24|32,33|35,57|59,65|67,68|71,71|73,83 ??S??S?HHHHHHHHHHHHHTTSSS------?EE?HHHHHHHHHHHHHHHHHHHHHHH-HHHHHTT?SE--E?HHHHHHHHHHT 1TAF|A PF00126.22_HTH_1_seed 1536 85 !Q:14,14|22,22|26,30|44,44|49,54|56,78|80,80 Q:0,13|15,21|23,25|31,43|45,48|55,55|79,79|81,84 HHHHHHHHHHHHHS-SHHHHHH-HHT?---?HHHHHHHHHHHHH-HHTS?----?B?--?----??---?---?--?-?B?HHHH 3ISP|A PF00127.15_Copper-bind_seed 31 129 !Q:0,2|9,9|13,13|16,16|22,22|25,25|34,35|38,39|44,44|46,47|66,66|73,73|76,76|79,79|83,85|87,87|90,90|102,102|105,106|111,111|113,113|115,115|121,121|128,128 Q:3,8|10,12|14,15|17,21|23,24|26,33|36,37|40,43|45,45|48,65|67,72|74,75|77,78|80,82|86,86|88,89|91,101|103,104|107,110|112,112|114,114|116,120|122,127 ???EEEEEB?TTS?BS?SEEEE?TT?SEEEEEEE??SS??HHHH?B??EEEEHHHHHHHHHHHHHH?GGGTTS?TT?TT?SEE???B?TT?EEEEEEEGGGS?TT??EEEE?T-T-TGGGT?EEEEEE? 2HXA|A PF00128.19_Alpha-amylase_seed 31 482 !Q:0,1|11,12|17,24|27,28|33,35|38,54|61,61|68,68|72,73|87,88|91,91|98,99|102,103|109,119|126,126|129,129|131,132|138,140|142,142|144,145|147,153|157,157|160,160|163,169|179,184|194,194|197,197|201,201|204,204|210,218|226,229|239,246|257,259|262,269|271,274|276,276|278,279|286,286|302,305|309,310|316,316|319,323|332,332|336,336|338,338|340,342|345,346|357,359|365,372|390,392|395,396|399,399|401,402|406,414|421,421|424,424|427,436|453,453|466,471|474,476|480,481 Q:2,10|13,16|25,26|29,32|36,37|55,60|62,67|69,71|74,86|89,90|92,97|100,101|104,108|120,125|127,128|130,130|133,137|141,141|143,143|146,146|154,156|158,159|161,162|170,178|185,193|195,196|198,200|202,203|205,209|219,225|230,238|247,256|260,261|270,270|275,275|277,277|280,285|287,301|306,308|311,315|317,318|324,331|333,335|337,337|339,339|343,344|347,356|360,364|373,389|393,394|397,398|400,400|403,405|415,420|422,423|425,426|437,452|454,465|472,473|477,479 ??HHHHHTTHH--HHHH--------HT??EEEE???EE---------???-----TTTTSS?SEEEEE?GGG??HHHHHHHHHHHHH--TT?EEEEEE??SB??TTSHH-----------HHHHTT?TT?T--TGGGB?--E-E??S-------SSS?SS?BB?------TTSSBSEEE------ETTTTEEEE?SS?TTS?BB?TTSHH---------HHHHHHH----HHHHHHHTT------??EEEETTGGGS???TT????????S----S?B??GGGTTT?TTHHHHHHHHHHHTG----GGS??EEEEE?TT??---HHHHHHHH?GGG?S?S--?EE??GGGSTTEETT---EEEEE????----HHHHHHHHHHHHHHTSS---SS??EE?S??TTS??-------HHHHTS?SS-TT----------HHHHHHHHHHHHHTSS-SEEEEETTGGGT??????SS---GGG?? 1JI2|A PF00129.13_MHC_I_seed 25 181 !Q:0,1|12,13|19,19|42,44|47,47|55,56|87,88|92,93|104,104|108,108|127,127|132,132|156,156 Q:2,11|14,18|20,41|45,46|48,54|57,86|89,91|94,103|105,107|109,126|128,131|133,155|157,180 ??EEEEEEEEEE??TTSSS?EEEEEEEETTEEEEEEETTSSS???EE?SGGGTTS?-HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??TTS??EEEEEEEEEE?TTS?EEEEEEEEEETTEEEEEE?TTSS?EEESSHHHHHHHHHHHHTTHHHH-HHHHHHTHHHHHHHHHHHHTHHHH 1A9E|A PF00130.17_C1_1_seed 46 77 !Q:0,1|5,15|17,18|20,20|24,25|27,40|44,44|50,53|56,57|60,60|63,64|70,70|72,72|76,76 Q:2,4|16,16|19,19|21,23|26,26|41,43|45,49|54,55|58,59|61,62|65,69|71,71|73,75 ??EEE?------??-?S??B?SSS??B?----------??-SSS?SEEES----SS??EE?TT--TTTTS?S?TTT? 1WEV|A PF00131.15_Metallothio_seed 21 81 !Q:0,1|3,4|6,10|12,12|14,14|17,20|23,24|26,28|31,33|36,39|41,41|46,46|49,52|57,58|61,62|64,64|66,71|73,73|75,76|79,80 Q:2,2|5,5|11,11|13,13|15,16|21,22|25,25|29,30|34,35|40,40|42,45|47,48|53,56|59,60|63,63|65,65|72,72|74,74|77,78 ??T--T---??S?S-SS????TT-?S?-?SS???TT????S-STTS?TT?---TTTT--TS??S?T------T?S??SS?? 4MT2|A PF00132.19_Hexapep_seed 216 36 !Q:0,0|4,4|7,7|10,10|13,13|16,16|19,19|22,22|28,28|31,31|34,34 Q:1,3|5,6|8,9|11,12|14,15|17,18|20,21|23,27|29,30|32,33|35,35 ?EEE?SS?EE?TT?EE?TT?EE?SSEEE?TT?EE?S 3FS8|A PF00133.17_tRNA-synt_1_seed 15 742 !Q:11,11|22,22|24,24|26,29|32,35|40,42|64,64|66,70|74,75|87,87|89,90|93,96|99,99|127,128|130,130|134,134|158,158|176,177|182,183|190,205|211,212|214,222|229,230|234,235|237,238|242,242|248,249|251,255|258,266|271,275|288,289|292,300|304,304|307,309|311,312|314,320|322,323|326,332|335,336|340,340|342,344|346,346|350,350|362,374|378,380|383,401|404,404|408,408|426,429|443,444|446,446|457,457|461,467|478,481|490,490|502,504|507,507|511,511|515,515|517,519|522,522|526,526|529,530|533,534|547,547|555,555|564,566|569,569|573,574|577,579|582,582|597,601|606,609|640,646|655,656|659,659|663,666|671,674|681,717|720,720|730,730|733,733|737,737|740,741 Q:0,10|12,21|23,23|25,25|30,31|36,39|43,63|65,65|71,73|76,86|88,88|91,92|97,98|100,126|129,129|131,133|135,157|159,175|178,181|184,189|206,210|213,213|223,228|231,233|236,236|239,241|243,247|250,250|256,257|267,270|276,287|290,291|301,303|305,306|310,310|313,313|321,321|324,325|333,334|337,339|341,341|345,345|347,349|351,361|375,377|381,382|402,403|405,407|409,425|430,442|445,445|447,456|458,460|468,477|482,489|491,501|505,506|508,510|512,514|516,516|520,521|523,525|527,528|531,532|535,546|548,554|556,563|567,568|570,572|575,576|580,581|583,596|602,605|610,639|647,654|657,658|660,662|667,670|675,680|718,719|721,729|731,732|734,736|738,739 HHHHHHHHTTH-HHHHHHHTTT-S?B--??EE????BSSS???HHHHHHHHHHHHHHHHHHTTT?B?????EEB??SHHHHHHHHHH-T??ST----TT?HHHHHHHHHHHHHHHHHHHHHHHHTTT??S?TTS?EETTSHHHHHHHHHHHHHHHHTT?EEEEEEEEEEETTTTEE??GGGE--EEEEEE----------------EEEEE??B??------?SSTTGG--GTT??B??EES?GGGSS??B?????TT???????--TTTT?????HHHHHHHHTTTT??SS?????????TTT?TT???B??T-------T??SB?????-?SS??SSS?S???B?TTS?SHHHHTTTSSS?-----???????SSS???TT?------------------SS?SSS?SSHHHHTTGGGSSHHHH????EEEEEEEEEETTT??B?EEEEEEEEEE?HHH-------HHHHHHHHHH----TSEESSHH-HHHHHHHHHHH???EE?EES?SSS?B???EE?TTS?EE??HH--HHHHHHHHHHHH?THHHHHS?HHHHSSTT???SS?TTS??EE???EE?HHHHHHTHHHHTTT-----TSTT??--SSBSEEEEEGGGGTTHHHHHHHHHHHHHSS?------SBSEEEEE??EE?TTS????SSSS????HHHHHH-------------------------------------HT?HHHHHHHHH-TS?TTS?EE?? 3U20|A PF00134.18_Cyclin_N_seed 127 184 !Q:13,17|23,23|25,25|27,29|31,32|34,34|47,47|54,55|73,81|99,106|109,109|111,125|127,129|138,142|145,145|148,163|181,183 Q:0,12|18,22|24,24|26,26|30,30|33,33|35,46|48,53|56,72|82,98|107,108|110,110|126,126|130,137|143,144|146,147|164,180 HHHHHHHHHHHHT--???TTGGG-G?S---S??H-HHHHHHHHHHHH-HHHHTT??HHHHHHHHHHHHHHHTT?-?----??TTTHHHHHHHHHHHHHH--------HH?S---------------S???HHHHHHTT-----TT-SS?---------------HHHHHHHHHHHHHHTTT??? 3EID|B PF00135.23_COesterase_seed 123 884 !Q:0,41|50,54|59,59|64,65|68,72|74,74|84,84|86,89|96,114|119,119|122,124|126,132|137,147|155,156|158,176|178,178|180,183|190,190|193,194|197,240|248,249|254,266|268,275|279,279|289,289|294,298|304,306|309,309|313,334|336,336|381,390|394,396|400,400|408,409|412,412|416,417|419,419|436,438|443,460|468,468|471,471|481,482|485,485|489,489|492,506|509,523|525,526|529,546|551,551|553,558|566,566|568,570|576,576|594,595|597,598|601,605|609,643|655,656|660,667|676,677|683,683|686,686|690,690|706,706|722,722|728,731|733,740|742,743|745,745|749,749|769,796|804,804|819,819|821,834|836,848|852,852|861,863|873,879 Q:42,49|55,58|60,63|66,67|73,73|75,83|85,85|90,95|115,118|120,121|125,125|133,136|148,154|157,157|177,177|179,179|184,189|191,192|195,196|241,247|250,253|267,267|276,278|280,288|290,293|299,303|307,308|310,312|335,335|337,380|391,393|397,399|401,407|410,411|413,415|418,418|420,435|439,442|461,467|469,470|472,480|483,484|486,488|490,491|507,508|524,524|527,528|547,550|552,552|559,565|567,567|571,575|577,593|596,596|599,600|606,608|644,654|657,659|668,675|678,682|684,685|687,689|691,705|707,721|723,727|732,732|741,741|744,744|746,748|750,768|797,803|805,818|820,820|835,835|849,851|853,860|864,872|880,883 ?????????????????????????-----------------TTEEEETT-----EEEE?EEEE?-SS-----S-EEEEEEEEE?S????GGGTTS????-----???----?-?SEEE?SS???B???????SSTT----------?HHHHTTS??S?------------------B?S?-??EEEEEE?SS??SS--------------------------------------------EEEEEEE??STTT?----------??S------??GGG?THHHHHHHT?EEEE?????HHHHH???TT?SSS---------------------?S?HHHHHHHHHHHHHHHHGGGGTEEEEEEEEEEETHHHHHHHHHHH?---------TTT---GGG?SEEEEES??TT?TTS-?B?HHHHHHHHHHHHHHTT???SSHH------------------HHHHHHH-HS?HHHHHHHGG--GG?SSS?SS?-------------?SS??-------------B??SS------------------SSSS?H------HHHHHHT?S?-?SEEEE-EEETBTTHHHHHHHSTT??T--TS?????HHH-----------------------------------HHHHHHHHSTT??HHH--------HHHHHHHH??TTSTT?HH-HHH-HHHHHHHHHHHTHHH-HHHHHHHHHHHSSEE-EEEEE????T--------T??S?GGG?SBTTTTHHHHTTGGGSGGG??-------------------------?HHHHHHH-HHHHHHHHHHHHHS?S--------------S?????????????TTT?EEEEESSS???EEESTTHHH-------HHHH 2VJB|A PF00136.16_DNA_pol_B_seed 67 884 !Q:0,0|20,20|22,112|116,116|118,118|121,124|141,147|154,154|156,255|261,262|266,272|277,278|281,281|286,286|291,293|298,299|311,316|329,329|333,345|369,369|373,373|376,377|405,405|414,414|420,440|443,443|446,447|455,455|467,467|469,490|509,518|521,521|537,537|547,556|558,559|561,561|567,568|570,571|575,575|592,592|599,605|611,621|624,624|632,634|639,644|659,659|662,662|664,667|671,671|673,729|734,734|739,799|802,803|806,806|809,809|816,825|827,827|834,834|851,868|881,881 Q:1,19|21,21|113,115|117,117|119,120|125,140|148,153|155,155|256,260|263,265|273,276|279,280|282,285|287,290|294,297|300,310|317,328|330,332|346,368|370,372|374,375|378,404|406,413|415,419|441,442|444,445|448,454|456,466|468,468|491,508|519,520|522,536|538,546|557,557|560,560|562,566|569,569|572,574|576,591|593,598|606,610|622,623|625,631|635,638|645,658|660,661|663,663|668,670|672,672|730,733|735,738|800,801|804,805|807,808|810,815|826,826|828,833|835,850|869,880|882,883 ?STHHHHHHHHHHHHHHTEE?B??????????????????????----------------------??????????????????????????????????????????????-EEE?S?EE----EEEEETHHHHHHHHTT-----??TTTEES?S----------------------------------------------------------------------------------------------------TTSTT??TTT-------TEEE--EE?SSSE-EEEE?--TTTS??HHHHHHHHHHH------HHHHHHHHGGGS?HHH-------------HHHHHHHHHHHHHHHHHHHHHHH?TTS-SS??HHHHHHHHHHHHHHHHHHHHHHHHHHS-SHHHHHHH?GGGGG---------------------GB?SS??EEEEEEE?SSEEEEEEETB?S----------------------TTHHHHHHHHHHHHHHHH--------??TT?EEEEEEEEEEEEEEE-TTEEEEEET----------T--S?EEEES??S??TTS?HHHHHHHHHHHHHHHH?HHHHHH-------HHHGG-----------GS?HHHHHHS???GGGH------HHHHHHHHHHHHHH-SS?S--??GGG?B?????--????????????---------????????????-----------??????TTTS?BEEB?????????????????????????????????????????????????????????????SS??EE?HH-HHHHTT--------??B?HHHHHH-HHHHHHHHHSGGGGTT-----------------?HHHHHHHHHTTS?GG 3K5N|A PF00137.16_ATP-synt_C_seed 167 73 !Q:4,4|35,35|68,69 Q:0,3|5,34|36,67|70,72 HHHH-HHHHHHHHTTHHHHHHHHHHHHHHHHHHHH?GGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--HHS 1IJP|A PF00139.14_Lectin_legB_seed 47 355 !Q:0,0|7,14|17,22|25,31|40,40|43,50|54,54|57,58|60,67|73,73|75,75|77,77|79,79|87,87|89,89|92,95|97,97|101,106|108,115|118,118|126,128|130,133|136,138|147,147|150,155|157,159|167,167|169,173|176,182|189,189|191,197|200,201|203,204|217,217|221,241|244,247|249,251|253,253|276,290|296,296|303,305|309,309|312,314|316,321|332,334|338,339|342,346 Q:1,6|15,16|23,24|32,39|41,42|51,53|55,56|59,59|68,72|74,74|76,76|78,78|80,86|88,88|90,91|96,96|98,100|107,107|116,117|119,125|129,129|134,135|139,146|148,149|156,156|160,166|168,168|174,175|183,188|190,190|198,199|202,202|205,216|218,220|242,243|248,248|252,252|254,275|291,295|297,302|306,308|310,311|315,315|322,331|335,337|340,341|347,354 ?EEEEEE--------SS?----?SS?------TTEEEEET?EE-------?TTS?EE-?S-------?EETTE-E?S-S?EEEEEES-S?EE?---B?TTT??----B-------?EE-EEEEEEE???S?--?SS???EEEEEEEE?SS??--??B--?GGGTTTB?T-----TS---????EEEEEE?S?-----?TT??S--SSEEEEEESSSS?SEE---------------------EE????T---T?EEEEEEEEETTTTEEEEEEEET---------------TTTEE-EEEEEE?-?HHH-HS?--S------EEEEEEEEEE-??GGG??TT?????EEEEEEEE 1QNY|A PF00140.15_Sigma70_r1_2_seed 183 39 !Q:0,1|14,18|37,37 Q:2,13|19,36|38,38 ??HHHHHHHHHTTS-????HHHHHHHHHHHHHHHHHH-H 4KN4|X PF00141.18_peroxidase_seed 162 647 !Q:11,19|25,27|30,38|46,86|90,104|106,106|113,113|115,119|124,125|129,129|133,133|136,137|140,144|147,164|167,171|181,182|185,185|188,189|191,193|195,195|201,217|228,246|248,259|261,270|272,273|276,276|278,280|282,282|286,286|291,368|370,370|372,373|377,377|383,383|388,391|399,399|401,438|443,444|446,446|450,450|456,464|469,470|472,472|474,485|488,488|493,495|499,500|505,509|513,513|516,531|536,537|539,540|544,560|563,563|574,609|611,612|622,625|629,634|646,647 Q:0,10|20,24|28,29|39,45|87,89|105,105|107,112|114,114|120,123|126,128|130,132|134,135|138,139|145,146|165,166|172,180|183,184|186,187|190,190|194,194|196,200|218,227|247,247|260,260|271,271|274,275|277,277|281,281|283,285|287,290|369,369|371,371|374,376|378,382|384,387|392,398|400,400|439,442|445,445|447,449|451,455|465,468|471,471|473,473|486,487|489,492|496,498|501,504|510,512|514,515|532,535|538,538|541,543|561,562|564,573|610,610|613,621|626,628|635,645 HHHHHHHHHHH--------?THHHH---HH---------HHHHHHH-----------------------------------------HTT---------------T-SSSSGG-G???--BTTB??STT-STT-TT--TT??--?HH------------------HH-----HHHHHHHHH--HS-TT--T---S?HHHHH-----------------HHHHHHHHHH-------------------T------------T??--??-???B??BB?S???H-HHH-HHHS-----------------------------------------------------------?-----------------?T-T??HHH-HHHHH-HTTT-?-?HHHHHHH-H--------------------------------------GGGG--B?EEE-HHHHH---------HHHH--H?S------------SS?HHHH---HHH--HTTS----?SSS?TT?---------------EEES-?S--SST-----------------BS?STHHHHHHHT------------------------------------T??SSHHHHHTS----SSS------TTHHHHHHHHH?- 1AEV|A PF00142.13_Fer4_NifH_seed 14 282 !Q:6,7|28,30|36,37|41,41|44,44|49,49|51,54|64,64|66,66|69,70|75,75|87,91|95,96|113,113|115,116|119,119|126,127|131,132|143,145|152,152|175,175|177,178|187,188|190,190|207,209|213,215|227,227|232,232|237,240|255,259|261,266|281,281 Q:0,5|8,27|31,35|38,40|42,43|45,48|50,50|55,63|65,65|67,68|71,74|76,86|92,94|97,112|114,114|117,118|120,125|128,130|133,142|146,151|153,174|176,176|179,186|189,189|191,206|210,212|216,226|228,231|233,236|241,254|260,260|267,280 EEEEEE??TTSSHHHHHHHHHHHHHHTT-??EEEEE??SSS?SS?TTTT?S????HHHHHHHHS?T-TT??HHHH?EEEGGGEEEEE?????TTS??HHHHHHHHHHHHHHTT?S?-SS?SEEEEE??GGG??GGGSHHHHTT???EEEEEE?SSTTTTHHHHHHHHHHHHTTTT?S-?EEEEEEEE??S?TTHHHHHHHHHHHHTS???EEE???THHHHHHTTTS?TTTS?SSSH----HHHHHHHHHHHHHH??-??B??????HHHHHHHHHHHSTT? 1XCP|A PF00143.14_Interferon_seed 15 167 !Q:0,8|19,20|22,22|26,26|30,36|41,50|72,72|76,76|98,111|116,118|138,138|157,166 Q:9,18|21,21|23,25|27,29|37,40|51,71|73,75|77,97|112,115|119,137|139,156 ?????????HHHHHHHHHT??S?GGG?TTT???????GGGG??????????HHHHHHHHHHHHHHHTSHHHH-HHS?HHHHHHHHHHHHHHHHHHHHH??????????????HHHH---HHHHHHHHHHHHHHHHTTT?HHHHHHHHHHHHHHHHHH-????????? 2KZ1|A PF00144.19_Beta-lactamase_seed 127 649 !Q:10,35|39,39|44,55|70,84|87,93|101,105|107,108|110,115|117,117|121,121|134,134|142,157|159,169|175,197|201,201|203,219|221,223|229,229|238,238|241,243|246,247|250,251|255,277|286,288|291,302|308,311|317,317|328,329|331,338|351,367|369,370|372,372|375,375|379,380|388,389|392,392|399,403|411,458|461,461|470,490|495,495|499,499|508,517|534,534|537,538|545,546|562,562|565,565|573,575|586,593|596,596|607,616|623,625|630,632|648,648 Q:0,9|36,38|40,43|56,69|85,86|94,100|106,106|109,109|116,116|118,120|122,133|135,141|158,158|170,174|198,200|202,202|220,220|224,228|230,237|239,240|244,245|248,249|252,254|278,285|289,290|303,307|312,316|318,327|330,330|339,350|368,368|371,371|373,374|376,378|381,387|390,391|393,398|404,410|459,460|462,469|491,494|496,498|500,507|518,533|535,536|539,544|547,561|563,564|566,572|576,585|594,595|597,606|617,622|626,629|633,647 HHHHHHHHHH--------------------------HHT?SEEE------------EEEEETTEEEEEEE---------------EE-------EETTTTE-----E??T------T?BEE?GGGHHHHHHHHH-HHHHHTT----------------S---------??TTSBH-----------------------HHH?T-----------------T???GGGTT?BHHHHHTT?SS???SS??TT??SHH-----------------------HHHHHHHH???SS?-----------TTSEE?-??HHHHH-HHHHHHTTTT--T-??-----HHHHHHHHTTTT-----------------T--T?TT?BSS??GGGGGGB??EE-ETTEEE?????TTHHHHT----------------------------------------------??EE?HHHHHHHH---------------------HHHH?GGG?SSHHHHHH----------HHHHTSEEEEETTEEE?SS-?EEEESS??HHHHHHHHSHHHHTS?EE?EEEEEEE???SSEEEEEEEE-------?SS?EEEEEEEGGG----------TEEEEE---EESB???HHHHHHHHHHHHHHT? 1IYP|A PF00145.12_DNA_methylase_seed 31 546 !Q:0,0|7,7|10,10|21,32|40,41|44,48|57,62|69,69|74,74|77,80|83,89|95,98|106,113|120,122|136,141|159,161|176,177|182,188|199,200|203,204|217,245|248,250|254,273|281,282|285,290|296,297|306,306|309,321|324,331|336,378|382,385|387,390|392,392|396,424|426,426|430,432|442,443|445,476|482,483|485,485|492,492|497,498|501,510|515,521|531,532|546,546 Q:1,6|8,9|11,20|33,39|42,43|49,56|63,68|70,73|75,76|81,82|90,94|99,105|114,119|123,135|142,158|162,175|178,181|189,198|201,202|205,216|246,247|251,253|274,280|283,284|291,295|298,305|307,308|322,323|332,335|379,381|386,386|391,391|393,395|425,425|427,429|433,441|444,444|477,481|484,484|486,491|493,496|499,500|511,514|522,530|533,545 ?EEEEES?SS?HHHHHHHHHT-----------?EEEEEEE??HH-----HHHHHHHH??----SEEEES?TTTS?GG----GS??----?SEEEE????TTTSSSS?----???SSSHHH---HHHHHHHHHHHHH?----?SEEEEEEEGGGGSGGGH---HHHHHHHHHHHHHH--EEEE-------EEEEEGGGGT-?SB??EEEEEEEEEGGG???-------------------???????SS???GGG--------------------TTGGGTT??EE?-----BTTTB??GGGSSSTT?EE??-------????HH--------HHTS??--------------------------------------???TTS---?B????S?GGG?---------------------------?B?TTS???EEEETTEEE??T--------------------------------TTGGG??B?BHHHHH-HHHT??TT-----?????SBHH-------HHHHHHHTS??HHHHHHHHHHHHH- 8MHT|A PF00146.16_NADHdh_seed 23 341 !Q:34,37|40,40|58,62|66,66|88,90|92,92|96,99|102,102|126,126|155,155|160,161|163,163|174,177|180,180|205,205|209,209|212,212|216,217|223,224|247,247|253,253|256,280|284,285|308,311 Q:0,33|38,39|41,57|63,65|67,87|91,91|93,95|100,101|103,125|127,154|156,159|162,162|164,173|178,179|181,204|206,208|210,211|213,215|218,222|225,246|248,252|254,255|281,283|286,307|312,340 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS????SS?SSSTTHHHHHHHHHTTS?????TTS?HHHHHHHHHHHHHHHHTTSTT???S?SSS-???SS?HHHHHHHHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHH??S?HHHHHHHHHH----TT?THHHHHHHHHHHHHHHHHTTTSSS?TTT?ST-TSS??SSSSS??SHHHHHHHHHHHHHHHHHHHHH-HHHTS?SS?-----------------------?SSS??HHHHHHHHHHHHHHHHHHHHHH????TTHHHHHHHHHTHHHHHHHHHHHHHHHHH 4HEA|H PF00147.13_Fibrinogen_C_seed 11 272 !Q:11,12|14,15|17,20|26,26|32,34|41,41|46,47|58,58|60,64|71,71|74,74|78,79|82,82|85,86|89,89|93,94|106,108|117,117|121,121|133,134|140,140|149,149|152,153|158,159|162,163|171,172|175,177|183,184|187,189|191,191|194,195|201,201|203,206|208,209|213,213|221,222|227,228|231,231|238,239|248,248|250,257|260,261|271,271 Q:0,10|13,13|16,16|21,25|27,31|35,40|42,45|48,57|59,59|65,70|72,73|75,77|80,81|83,84|87,88|90,92|95,105|109,116|118,120|122,132|135,139|141,148|150,151|154,157|160,161|164,170|173,174|178,182|185,186|190,190|192,193|196,200|202,202|207,207|210,212|214,220|223,226|229,230|232,237|240,247|249,249|258,259|262,270 EESSHHHHHTT--T??S?---EEEEE?SSTTS-??EEEEEE?SGGG??EEEEEEESSS?S?????HHHHHH?EE?SEE??SS?SS??EE?SEE??HHHHHHHHTSS--?EEEEEEEE?TTS?EEEEEEEEEEE??TTTTT?EEEEEEEE-SS??HHHH??TT??HHHHHTT??TT???BBTTB??SS???S?TT??HHHHH?S?---B??SSB?SEETTSB??TTSB??TT-TSTTSS??BSEEHHHH?S--------SB??SEEEEEEEE? 1Z3U|A PF00148.14_Oxidored_nitro_seed 116 723 !Q:0,0|7,7|23,23|27,29|43,55|57,71|74,77|84,85|102,105|113,113|121,122|131,135|140,140|142,142|144,158|160,160|166,168|171,171|174,174|191,277|279,281|283,298|303,305|307,310|312,314|325,325|330,331|337,338|340,346|351,354|357,358|361,361|363,363|366,366|376,376|386,386|390,392|403,405|409,410|412,414|432,455|461,464|467,467|477,477|480,483|488,490|492,493|495,503|509,511|513,513|525,525|527,527|530,530|540,541|546,547|549,604|615,621|623,623|629,630|633,633|640,640|645,648|652,656|662,662|671,677|679,680|684,684|687,689|691,691|696,696|699,699|708,711 Q:1,6|8,22|24,26|30,42|56,56|72,73|78,83|86,101|106,112|114,120|123,130|136,139|141,141|143,143|159,159|161,165|169,170|172,173|175,190|278,278|282,282|299,302|306,306|311,311|315,324|326,329|332,336|339,339|347,350|355,356|359,360|362,362|364,365|367,375|377,385|387,389|393,402|406,408|411,411|415,431|456,460|465,466|468,476|478,479|484,487|491,491|494,494|504,508|512,512|514,524|526,526|528,529|531,539|542,545|548,548|605,614|622,622|624,628|631,632|634,639|641,644|649,651|657,661|663,670|678,678|681,683|685,686|690,690|692,695|697,698|700,707|712,722 ?THHHHH-HHHTTBTTEEEEEES?HHH---HHHHHHHHHHHHS-------------S??--?---------?EE????TTHHHH?-SHHHHHHHHHHHHHHT??--SEEEEEE?HHHHHHT??HHHHHHHH-----HHTT?S?T---------------T?EEEEE???TT-SS?HHHHHHHHHHHHHHHH-----------------------------------------------------------------------------------????S???S---------------?EEEE-??S-??-H---HHHHHHHHHH-HHHT??EEESS??T-------TTSS????SS??SS?S?SB?HHHHHTTSS?SEEEEESHH-HHH---HHHHHHHHHS???EEE--E???BHHHHHHHHHHHHHHHH?----------------??--?-?HHHHH----HH-HHHHHHHHH-TH----HHHT---T-?E---------EEEEE?--H-HHHHHHHHHHH-T-TT?EEEEEEESS??HHHH--H--------------------------------------------------------HHHHHHHTTT?-----?S?EEEES-?BH-HHHHHH-HHHS?--?SEE-----EESGG-GHHHHHHH-------T??EEE?SS???S?SSGG-GS?SSBTHHHH----HHHHHHHHHHH 2AFK|A PF00149.23_Metallophos_seed 324 477 !Q:6,6|8,8|11,11|16,60|68,69|74,74|76,76|79,80|82,83|89,89|98,165|179,181|200,322|326,326|340,342|356,358|361,363|370,371|374,377|385,427|431,431|434,434|437,437|443,443|452,452|465,466|471,472|474,475 Q:0,5|7,7|9,10|12,15|61,67|70,73|75,75|77,78|81,81|84,88|90,97|166,178|182,199|323,325|327,339|343,355|359,360|364,369|372,373|378,384|428,430|432,433|435,436|438,442|444,451|453,464|467,470|473,473|476,476 SSEEEE?B?TT?HHHH---------------------------------------------HHHHHHH??TTSS?E-EE-?S??SSSSS?HHHHHHHH--------------------------------------------------------------------HHHHHHSTTTEEE???TTSSHHHHTTSSHHHHHH---------------------------------------------------------------------------------------------------------------------------HHS?HHHHHHHHHHHTT???EEEETTTEEEESS???TT???THHHHT??SS????SSSHHHH-------------------------------------------HHH?EE?TT?SSEEE?TTSSSEEE?HHHHHHHHHHTT??EEEE??S??T 2DXL|A PF00150.13_Cellulase_seed 65 583 !Q:1,4|7,12|21,29|31,32|34,34|36,43|55,56|61,79|84,88|90,90|95,100|103,103|105,110|124,124|129,129|132,132|136,137|139,161|163,163|166,175|179,179|188,199|204,219|223,231|242,243|245,246|248,248|254,257|260,262|267,275|280,281|283,284|286,286|311,312|319,319|324,356|360,370|379,412|415,416|418,418|425,428|436,436|441,474|477,477|480,482|499,499|504,506|513,521|524,541|551,552|559,564|568,568|570,570|575,581 Q:0,0|5,6|13,20|30,30|33,33|35,35|44,54|57,60|80,83|89,89|91,94|101,102|104,104|111,123|125,128|130,131|133,135|138,138|162,162|164,165|176,178|180,187|200,203|220,222|232,241|244,244|247,247|249,253|258,259|263,266|276,279|282,282|285,285|287,310|313,318|320,323|357,359|371,378|413,414|417,417|419,424|429,435|437,440|475,476|478,479|483,498|500,503|507,512|522,523|542,550|553,558|565,567|569,569|571,574|582,582 T????SS?----?SGGGHHHH---------T--T?S?-----??HHHHHHHHHHT??EEEE???------?---------GGGE-----E-TTTT------EE?H------HHHHHHHHHHHHH-HTTT?EE-EEE??S?----------------------B?TT----------TSB?SSGGGHHH------------HHHH----------------HHH---------HHHHHHHHTT--T??T-TEEEE--??SS???TTST---------TTTS??T--T?HHHHHHHHHHHHHHHHHHHHHHHT-?GGGGTS?EEEE?--------------------------------GGG----------?HHHHHSTT---????------------------??------?TT??S?EEEEEE???-SHHHHTS?GGGT??----------------------------????TT?HH---HHHHHHHHHHHHHHHT-GGGT?-?EEEEEE???-----?SS?-----------------HHHHHHHHH--HHHHHH------HHT-T?EEEE-??????S 4IPL|A PF00151.14_Lipase_seed 16 379 !Q:0,0|4,4|8,8|12,12|19,19|24,32|38,40|51,52|59,59|70,72|82,83|85,86|89,111|126,129|137,137|144,144|171,173|199,203|212,212|214,214|221,221|226,227|238,238|240,241|243,243|248,250|252,253|255,256|268,270|273,279|281,283|293,296|312,314|317,317|319,319|321,321|324,324|326,326|334,334|336,336|338,339|342,347|353,353|357,357|371,373|378,378 Q:1,3|5,7|9,11|13,18|20,23|33,37|41,50|53,58|60,69|73,81|84,84|87,88|112,125|130,136|138,143|145,170|174,198|204,211|213,213|215,220|222,225|228,237|239,239|242,242|244,247|251,251|254,254|257,267|271,272|280,280|284,292|297,311|315,316|318,318|320,320|322,323|325,325|327,333|335,335|337,337|340,341|348,352|354,356|358,370|374,377 ?EEE?GGG?EEE?STTSSS-BTTB??????-??HHHHT--?EEEEEETTEE--EEEEEE?SSSTHHHHTS???TTSEEEEEE??S??TT----------------------?TTHHHHHHHHHHTT--??EEEEEEE?HHHHSS?HHHHHHHHHHHHHHHHHHHHHHHHHH???GGGEEEEEETHHHHHHHHHHHHTTT----?SSEEEEES?B?TTTTTS?GGGS??GGGSSSEEEE?S??S?HHHH???B??S??SSEEEEETTSS?-?TT???????S???HHHHHTTSS????HHHHHHHHHHHHHHH--?GG-G?B?EE?S?HHHHHTT?S?S??TT---???BSSGG-GGG?TTTTSSSSEEEEE???SSTT? 1BU8|A PF00152.15_tRNA-synt_2_seed 107 593 !Q:0,0|20,20|40,40|42,42|45,48|52,55|58,63|65,67|71,71|73,82|91,97|99,99|112,115|125,132|137,137|139,139|149,150|153,154|158,158|173,173|176,176|178,212|214,217|230,230|233,235|239,246|250,251|255,264|268,268|270,270|279,279|295,296|312,316|318,318|321,326|328,328|338,338|345,345|358,359|362,362|386,392|396,402|405,405|407,411|415,416|422,423|428,431|433,433|438,450|456,456|460,462|466,471|477,488|494,494|506,507|517,519|532,538|556,560|578,578|580,580|588,590 Q:1,19|21,39|41,41|43,44|49,51|56,57|64,64|68,70|72,72|83,90|98,98|100,111|116,124|133,136|138,138|140,148|151,152|155,157|159,172|174,175|177,177|213,213|218,229|231,232|236,238|247,249|252,254|265,267|269,269|271,278|280,294|297,311|317,317|319,320|327,327|329,337|339,344|346,357|360,361|363,385|393,395|403,404|406,406|412,414|417,421|424,427|432,432|434,437|451,455|457,459|463,465|472,476|489,493|495,505|508,516|520,531|539,555|561,577|579,579|581,587|591,592 ?HHHHHHTHHHHHTSHHHHH-HHHHHHHHHHHHHHHHHHT-T?EE????SSB????SS------S???EEE?S----------SSTTEEEE-----??S?SHHHHHHHHHTT-?-?EEEEEEEEE?????---BTTB?S-EEEEEEEEE--ES??HHH-HHHHHHHHHHHHHH-HH-T-----------------------?????-------S--??EEEHHHHHHHHS?SS-??TTS-??----?EEE-?TGG----------GSS?S?HHHHHHHT?TTEEEEEEEETTGGG??TTHHHHHHHHGGGGT?????B?EE------S?GGGGGGGEE?TTTTTS?HHHHHHHHHHHT??TT?EEEEEEEEHHHHHHHHHHHHHHH-------HHH-------TT?S----?TTS??EEEEE??BSEE----E?SSSS-------------EEESS?TTB?--BSS---??-HHHHT------------TSTTT?BBSEEEEEETT--EEEEEEEEB???HHHHHHHHHHTT??-----HHHHHHHHHHHHHHTTB-????EEEEEEEHHHHHHHHHT?S?GGGGSSS???TT 2ZCE|A PF00153.22_Mito_carr_seed 188 152 !Q:18,18|37,52|55,63|66,67|70,70|72,74|81,91|97,97|101,109|111,111|135,138|151,151 Q:0,17|19,36|53,54|64,65|68,69|71,71|75,80|92,96|98,100|110,110|112,134|139,150 SSSTTHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHG----------------GG--------?SS??TT-T??-SSHHHH-----------HHHHH-HHH?--------G-GGGGTTHHHHHHHHHHHHHHHHH----HHHHHHHHHTTT? 2LCK|A PF00154.16_RecA_seed 28 329 !Q:14,14|19,20|23,31|34,35|37,37|59,59|81,82|90,93|102,103|107,107|111,112|130,131|138,138|142,144|150,155|180,180|187,204|207,207|214,214|231,234|252,255|268,268|311,311|327,328 Q:0,13|15,18|21,22|32,33|36,36|38,58|60,80|83,89|94,101|104,106|108,110|113,129|132,137|139,141|145,149|156,179|181,186|205,206|208,213|215,230|235,251|256,267|269,310|312,326 HHHHHHHHHHHHHH?TTSS??TT???-?????EE??S?HHHHHHTSSSSEETTSEEEEE?STTSSHHHHHHHHHHHHHHTT??EEEEESS????HHHHHHTT??GGG?EEE??SSHHHHHHHHHHHHHHT??SEEEEE?GGG???HHHHT??????HHHHHHHHHHHHHHHHHHHHHHHT?EEEEEE?????????-??-?????TT?HHHHHH?SEEEEEEEEEEEEETT----EEEEEEEEEEEEEESSS????EEEEEEETTTEE?HHHHHHHHHHHTTSSEEETTEEESSSSEEEESHHHHHHHHHH?HHHHHHHHHHHHHHH?? 1N03|A PF00155.16_Aminotran_1_2_seed 48 526 !Q:3,3|6,9|14,18|27,27|34,42|49,51|54,55|64,68|74,78|83,88|90,92|95,95|97,97|115,122|125,125|127,127|134,135|147,148|154,156|159,168|172,174|190,198|208,208|212,216|231,231|233,233|239,239|245,246|250,272|286,287|302,302|304,304|308,308|316,316|318,336|350,355|368,368|375,380|404,408|410,411|413,415|417,417|426,426|430,430|433,439|452,475|480,480|482,482|485,485|493,493|495,499|503,503|509,510|514,514 Q:0,2|4,5|10,13|19,26|28,33|43,48|52,53|56,63|69,73|79,82|89,89|93,94|96,96|98,114|123,124|126,126|128,133|136,146|149,153|157,158|169,171|175,189|199,207|209,211|217,230|232,232|234,238|240,244|247,249|273,285|288,301|303,303|305,307|309,315|317,317|337,349|356,367|369,374|381,403|409,409|412,412|416,416|418,425|427,429|431,432|440,451|476,479|481,481|483,484|486,492|494,494|500,502|504,508|511,513|515,525 BEE?SS????SSHH-----HHHHHHHH?TTSSTT---??????HHHHHH???TT??HHHHHHHH-----HHHHH-----HTTT-----?S???TT-S?EEEEHHHHHHHHHHHHH------??TT?E-EEEESS??TTHHHHTTTTT??EEEEE???TT----------TTT???HHHHHHHHHHHHHTT?-------?EEEEEEESS?TTT?????HHHHHHHHHHHHTT-T?EEEEE?TTGGG??SSS--????-----------------HHHHHTSGGGTTS?-TTSEEEEEESTTTS-S?GGG?EEEEEES?H-------------------HHHHHHHHHHTTS??---?HHHHHHHHHHTT?HHHHHH------HHHHHHHHHHHHHHHHHHHHHHT-----T??B???S-SSSEEEEE?GGG?SS-------SSHHHHHHHHHH------------------------HHHT-S?EE?EEGGGGT?S-----SSS-EEEEE?-SSS?HHHHHHHHHHH 3ATH|A PF00156.22_Pribosyltran_seed 71 196 !Q:0,0|4,8|19,24|29,32|37,38|41,48|70,73|81,132|135,135|140,142|144,145|148,148|154,154|161,161|170,170|174,174|178,178|181,187|196,196 Q:1,3|9,18|25,28|33,36|39,40|49,69|74,80|133,134|136,139|143,143|146,147|149,153|155,160|162,169|171,173|175,177|179,180|188,195 ?EEE---??HHHHHHHHHH------HHHH----HHHH??SE--------EEEETTTTHHHHHHHHHHTTS--??EEEEEEE?-------------------------------------------????????SS?EEEE???S??BT?EEEEE-EEEESS?HHHHHHHH-HHH-TTT-BS-------EEEEEEEE- 1O5O|A PF00157.12_Pou_seed 20 81 !Q:0,4|15,17|27,28|43,48|59,59|61,61|79,80 Q:5,14|18,26|29,42|49,58|60,60|62,78 ?????HHHHHHHHHH---HHHHHHHTT??HHHHHHHTHHHHSS?---??HHHHHHHHTT?S?HHHHHTTHHHHHHHHHS?? 1AU7|A PF00158.21_Sigma54_activat_seed 287 212 !Q:0,3|10,10|19,22|26,28|30,30|36,36|40,40|49,53|56,62|65,65|67,70|72,73|76,81|85,85|87,88|90,93|96,98|106,108|111,122|137,137|140,141|157,158|162,162|164,171|173,175|184,184|191,191|195,196|198,198 Q:4,9|11,18|23,25|29,29|31,35|37,39|41,48|54,55|63,64|66,66|71,71|74,75|82,84|86,86|89,89|94,95|99,105|109,110|123,136|138,139|142,156|159,161|163,163|172,172|176,183|185,190|192,194|197,197|199,211 ????SHHHHH-HHHHHHHH?---STT---S?EEEES?TTS?HHHHHHHH-----HH-------HS-S?---S--SS---???EEE?S--S?--?HH---HHHHHHT???SS??????????-?HHHHHTTSEEEEES?TT??HHHHHHHHHHHHSSB??BTT-B-?-?-?-?B???EEEEEESS?HHHHHH-HTS--S?HHHHHHHSSEEEE 2C99|A PF00159.13_Hormone_3_seed 21 40 !Q:0,10|13,13|18,19|39,39 Q:11,12|14,17|20,38 ??????--???SS?TTTT--HHHHHHHHHHHHHHHHHHH? 2H4B|C PF00160.16_Pro_isomerase_seed 168 580 !Q:4,5|11,15|18,18|20,20|26,29|31,32|36,37|46,46|48,56|59,77|82,82|84,99|106,107|109,110|112,112|116,121|123,123|125,134|138,140|142,149|152,162|164,179|181,199|202,228|233,251|255,268|270,270|272,349|351,364|367,368|374,375|379,397|400,404|406,407|409,409|413,418|421,450|452,477|479,485|488,489|491,498|500,509|512,513|520,521|523,526|529,529|536,536|538,545|547,552|556,567|570,571 Q:0,3|6,10|16,17|19,19|21,25|30,30|33,35|38,45|47,47|57,58|78,81|83,83|100,105|108,108|111,111|113,115|122,122|124,124|135,137|141,141|150,151|163,163|180,180|200,201|229,232|252,254|269,269|271,271|350,350|365,366|369,373|376,378|398,399|405,405|408,408|410,412|419,420|451,451|478,478|486,487|490,490|499,499|510,511|514,519|522,522|527,528|530,535|537,537|546,546|553,555|568,569|572,579 EEEE--EETTE-----EE-E-EEEEE----E-?TTT?-HHHHHHHH-H---------HH-------------------HTTT?B?---------------TTSSBS??T--T?BEE------E-E----------ETT---T--------EE-----------E----------------E??----------------?SS---------------------------SSSS???------------?---SSS--------------S?B?--???--?--------------------------------------------------------------------?S??-----------?ST--TEEEE?-BSS-------------------TT?----B-?S?EEE------ES------------------------------S?------------------------?G-------GG--T--------T----------TS-?EEEEEE--E?---HH-HHHHHH-H--------T?----?SSS----------??SS?-EEEEEEEE 1CWL|A PF00161.14_RIP_seed 73 294 !Q:6,7|9,10|26,26|29,29|31,36|40,41|45,52|58,58|66,66|68,70|73,76|78,78|88,89|98,99|108,108|110,113|116,116|118,118|129,131|133,134|140,144|146,148|158,158|160,163|168,168|170,170|172,172|186,186|188,223|244,244|256,263|266,266|268,273|293,293 Q:0,5|8,8|11,25|27,28|30,30|37,39|42,44|53,57|59,65|67,67|71,72|77,77|79,87|90,97|100,107|109,109|114,115|117,117|119,128|132,132|135,139|145,145|149,157|159,159|164,167|169,169|171,171|173,185|187,187|224,243|245,255|264,265|267,267|274,292 EEESTT??H--HHHHHHHHHHHHHHS?SS?E------ETT--EEB?-----??TTSSS?EEEEEEE?T---TS?---E-EEEEEETTT??EEEEEEEE--TTEEEEEE?T----TS?H-HHHHHHHHHH???T--TSEEE???-?S???HHHHHHHHT?S----SGGG-S?B?HHHHHHHHHHHTT?S??---------------------------------?HHHHHHHHHHHHHHHHHHHH?HHHHHHHHHTT--------TS?B???---HHHHHHHHHHHHHHHHHHH? 2JDL|A PF00162.14_PGK_seed 154 602 !Q:5,15|18,18|24,29|31,33|35,36|38,38|40,46|50,51|60,60|69,69|71,71|73,73|78,80|82,84|86,108|110,111|113,137|140,140|145,179|188,188|191,195|200,202|204,207|219,222|230,231|240,262|265,265|276,279|285,286|293,294|301,302|307,310|314,314|325,325|331,334|342,342|345,345|354,357|364,366|372,372|383,383|386,389|393,398|400,409|415,433|442,442|447,447|451,452|459,463|466,467|470,472|474,478|486,494|497,498|504,504|515,515|519,519|527,527|530,530|533,533|538,538|553,553|557,558|574,574|577,577|580,580|584,585|590,590 Q:0,4|16,17|19,23|30,30|34,34|37,37|39,39|47,49|52,59|61,68|70,70|72,72|74,77|81,81|85,85|109,109|112,112|138,139|141,144|180,187|189,190|196,199|203,203|208,218|223,229|232,239|263,264|266,275|280,284|287,292|295,300|303,306|311,313|315,324|326,330|335,341|343,344|346,353|358,363|367,371|373,382|384,385|390,392|399,399|410,414|434,441|443,446|448,450|453,458|464,465|468,469|473,473|479,485|495,496|499,503|505,514|516,518|520,526|528,529|531,532|534,537|539,552|554,556|559,573|575,576|578,579|581,583|586,589|591,601 BGGGS---------??TT?EEEEE??????E---E--T-T-------EES??HHHHHHHH-HHHHHHHT-T?E-EEEE???S???S-----------------------S??G-------------------------GG?SHHH-----------------------------------HHHHHHHH-TS?---?EEES?--S----SSHHHHHHHHT?--?TTEEEEE??GGGSTHHH-----------------------HT?HHHHHHHHTT?---SEEEE??GGGTTS??TTTTGG--GGTS---?EEE?HHHHHHHHHH-HHHHH??-?SSEEEEE?SS?HHHHHHHH----HHHTTT--?SEEEE?TTTHHHHHHH-TS-???TTS?---??G----------GGHHH-------------------HHHHHHHH-HHTT?EEE??SEEEEE-----SS-?ST---T?-??-EEEETTT-???-----TT-?EEEEE?HHHHHHHHHH-HTT?SEEEEES?SS?TT-SGGG?HHHHHHHHHHHHHH-HTT?-EEEEESHHHHHHHHH-TT?GG-GSS--EEES?HHHHHHHHTSS 2Y3I|A PF00163.14_Ribosomal_S4_seed 18 112 !Q:0,11|13,13|15,16|24,27|36,41|56,57|68,68|71,71|91,92|104,105 Q:12,12|14,14|17,23|28,35|42,55|58,67|69,70|72,90|93,103|106,111 ??-?????????S?S??THHHHHH----HHHHHHTT---???HHHHHHHHHHHHHH--HHHHHHHHHS?TT?HHHHHHHHHHHHHHHHTTS??SSTTSHHHHTT??THHHHT 3KIX|d PF00164.20_Ribosom_S12_S23_seed 18 145 !Q:0,1|9,28|30,32|36,36|38,38|50,52|55,56|58,58|68,69|72,72|78,79|82,88|91,91|96,106|112,114|117,117|123,126|128,129|131,132|135,135|140,145 Q:2,8|29,29|33,35|37,37|39,49|53,54|57,57|59,67|70,71|73,77|80,81|89,90|92,95|107,111|115,116|118,122|127,127|130,130|133,134|136,139 ??HHHHHHT?-----------????????S???STT?S?EEEEEEEEEEE???SS??S?EEEEEEEET--TS?EEEEE??SS?--????TT?EEEE????------?TTSTT???BB?TTSTT????T--T??SS?TTTT?????- 3KIX|l PF00165.18_HTH_AraC_seed 75 44 !Q:2,4|7,10|20,20|37,37 Q:0,1|5,6|11,19|21,36|38,43 HH---TS?-??SSHHHHTTT?SSSHHHHHHHHTTSSS?HHHHHH 1D5Y|A PF00166.16_Cpn10_seed 48 127 !Q:0,0|4,4|13,46|55,57|60,61|65,66|69,70|72,73|75,76|78,78|83,83|86,99|102,102|107,108|110,110 Q:1,3|5,12|47,54|58,59|62,64|67,68|71,71|74,74|77,77|79,82|84,85|100,101|103,106|109,109|111,126 ?EEE?SSEEEEEE--?-??-??---?????????--?????--??--EEEEEEEE???EE?-TTS?-EE??S??T--T?EEEE?TT?-------------SE-EEEE--T-TEEEEEEEGGGEEEEE 3ZQ1|O PF00167.13_FGF_seed 77 196 !Q:9,10|17,17|19,23|26,30|32,32|37,37|39,40|42,42|53,56|59,59|61,62|72,73|78,78|82,82|85,91|93,95|97,106|109,111|113,113|116,116|136,152|156,157|161,162|164,164|170,171|174,175|177,181|188,188|190,194|196,196 Q:0,8|11,16|18,18|24,25|31,31|33,36|38,38|41,41|43,52|57,58|60,60|63,71|74,77|79,81|83,84|92,92|96,96|107,108|112,112|114,115|117,135|153,155|158,160|163,163|165,169|172,173|176,176|182,187|189,189|195,195 TEEEEEETT--TEEEEE?T-----TS----?E-EEES?T--T?SSSEEEEEEE----ET-T--EEEEEETTT??EEEE?TTS?EE-------E---E----------SS??-G-GG?EEEEEEETTEEEEEEEEEE?----------------TTT??EEE??B?TTSSB??GG--G?---?TTSGGG?E-----E- 3O4D|A PF00168.25_C2_seed 382 191 !Q:10,13|15,56|60,64|77,80|83,109|112,116|118,120|123,123|127,131|137,141|148,152|160,160|162,163|167,183 Q:0,9|14,14|57,59|65,76|81,82|110,111|117,117|121,122|124,126|132,136|142,147|153,159|161,161|164,166|184,190 EEEEEEEEES????S------------------------------------------TTS--???EEEEEEEETEEE----EE---------------------------EE?????S?--SS?EEE-----EEEEE?--??GGGSTT?----EEEEEEE-E??SSS?---------------?EEEEEEE 3FBK|A PF00169.24_PH_seed 133 297 !Q:0,0|10,34|38,39|50,56|67,135|138,138|144,144|147,148|153,155|157,233|235,235|243,243|249,253|257,260|264,264|268,270|277,277|281,281|297,297 Q:1,9|35,37|40,49|57,66|136,137|139,143|145,146|149,152|156,156|234,234|236,242|244,248|254,256|261,263|265,267|271,276|278,280|282,296 ?SEEEEEEEE?-----------------------?SSS??EEEEEEEEET-------TEEEEESSTT--------------------------------------------------------------------?SS?SEEEE?TT?-EEEE???S-----------------------------------------------------------------------------S?SSEEEEE?TTSTT?????EEE---?TTS?EEE???SEEEEE?SSH-HHHHHHHHHHHHHHH- 1X05|A PF00170.16_bZIP_1_seed 22 64 !Q:0,4 Q:5,63 ---??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 1S9K|D PF00171.17_Aldedh_seed 119 604 !Q:2,3|6,13|15,15|20,20|23,27|29,30|37,40|43,43|55,55|59,65|71,71|75,75|92,92|108,109|112,114|123,123|126,130|141,142|146,148|150,150|153,158|160,162|164,172|183,183|185,187|193,194|203,203|215,215|221,223|226,227|231,231|241,241|243,246|248,249|256,260|262,263|273,273|275,275|278,278|286,286|297,297|300,300|304,312|318,327|332,332|336,338|340,340|352,352|358,359|362,364|372,372|377,378|388,388|390,393|396,399|401,401|404,411|413,413|415,416|418,420|422,422|441,441|444,444|446,458|462,462|466,467|470,471|475,477|480,482|491,493|503,512|517,517|523,523|526,527|534,534|548,551|558,566|570,572|574,575|581,581|584,586|590,590 Q:0,1|4,5|14,14|16,19|21,22|28,28|31,36|41,42|44,54|56,58|66,70|72,74|76,91|93,107|110,111|115,122|124,125|131,140|143,145|149,149|151,152|159,159|163,163|173,182|184,184|188,192|195,202|204,214|216,220|224,225|228,230|232,240|242,242|247,247|250,255|261,261|264,272|274,274|276,277|279,285|287,296|298,299|301,303|313,317|328,331|333,335|339,339|341,351|353,357|360,361|365,371|373,376|379,387|389,389|394,395|400,400|402,403|412,412|414,414|417,417|421,421|423,440|442,443|445,445|459,461|463,465|468,469|472,474|478,479|483,490|494,502|513,516|518,522|524,525|528,533|535,547|552,557|567,569|573,573|576,580|582,583|587,589|591,603 EE??TT------??E-EEEE?TT-----T??EEEEEE-???HH-HHHHHHHHHHH-HTS-------TTSHH-HHS?HHHHHHHHHHHHHHHH-HTHHHHHHHHHHHHT??HH---HHHHTHHH-HH-----HHHHHHHHHH--GGG-??E-EE------E??-S---------SSEEEEEEEE-E?-?EEEEE??SSSHHHHH-HHHHHHHHHTT?EEEEE-??TT??HHH-HHHHHHHHH-H----T??TTSEEE?---?S?-TTTHHHHHH-T?TT?SEEEEES?HHHHHHHHHH-HH-HTT---?----?EEEEE?????-----EEEE?TTS-?-H-HHHHHHHHHHH-HTTTT??TT???EEEEEHH-HHHH--HHHHHHHHH-T??-?BS?---T-TS--------T-T??B???S?HHHHHHHHHHHHHHHHTT?EE?S-??----------SEE?SSS-?EE??EEE---ES-??TTSHHHHS???SSEEEEEEE?--?------HHHH-HHHHH?SS??SEEEEE?SBHHHHHHHHHHS--??SEEEES??---????TTS--?B??SGGGE-ES--?BSH-HHHHHTTEEEEEE 2EHU|A PF00172.13_Zn_clus_seed 29 52 !Q:0,0|2,2|10,12|14,15|26,27|29,29|37,43 Q:1,1|3,9|13,13|16,25|28,28|30,36|44,51 ?S?HHHHHTT???S??TTHHHHHHHT??S?HHHHHHT--?????HHHHTTTS 3ALC|A PF00173.23_Cyt-b5_seed 210 160 !Q:2,2|11,21|33,33|38,38|41,41|46,46|49,63|75,75|80,129|134,140|150,152|159,159 Q:0,1|3,10|22,32|34,37|39,40|42,45|47,48|64,74|76,79|130,133|141,149|153,158 EE?HHHHHTSE-----------ETTEEEEEETT-EEEE?GG-GTTT?TT?--------------SHHHHTTTTEE?HHHH--------------------------------------------------HHHT---??--HHHHHHHGG---GEEEEE? 1CXY|A PF00174.14_Oxidored_molyb_seed 150 357 !Q:1,1|4,25|27,27|30,30|35,39|41,56|68,69|71,74|80,80|84,84|95,99|102,103|106,109|112,113|134,135|137,155|158,184|191,191|195,241|244,245|247,251|259,259|264,264|266,284|287,288|298,302|304,305|312,312|316,316|318,318|321,321|326,327|339,352 Q:0,0|2,3|26,26|28,29|31,34|40,40|57,67|70,70|75,79|81,83|85,94|100,101|104,105|110,111|114,133|136,136|156,157|185,190|192,194|242,243|246,246|252,258|260,263|265,265|285,286|289,297|303,303|306,311|313,315|317,317|319,320|322,325|328,338|353,356 E?SS?-??------------??-?--T-TT?EEEE-----E--?-------?-????EEEEHHHHHHH--S??--EEEEE-EEE?TTTTHHHHHT-----TS??SS????TT--SEEEEEEEEEEHHHHHHHTT??S?------------?-----SS?-------------------------?EEEEEE-EEE?----------------------------------------------TT??E-----EEEEEEH-HHHH?G-------------------GG??EEEEEETTE-----E??GGGTTT?EEE?T-TB?GGGS?-SSEEEEEEESS?-?------??---HHHH 2BIH|A PF00175.16_NAD_binding_1_seed 72 148 !Q:3,3|25,37|42,42|51,51|53,56|58,58|68,68|71,72|76,77|80,85|88,89|91,91|95,97|102,104|110,111|115,125|127,127|137,138 Q:0,2|4,24|38,41|43,50|52,52|57,57|59,67|69,70|73,75|78,79|86,87|90,90|92,94|98,101|105,109|112,114|126,126|128,136|139,147 EEE-ETTTTHHHHHHHHHHHTTTTT----------???EEEE-EEEESSGG-G??--S?HHHHHHHHH?TT--TEE??EE------ES??S?TTS???SEES???HHHHH--TTS??---------S?TTEEEEEES-?HHHHHHHTT 1IB0|A PF00176.18_SNF2_N_seed 28 973 !Q:13,124|128,129|133,135|141,154|164,185|193,212|214,505|510,511|513,513|528,528|530,530|532,535|539,541|550,601|607,607|609,620|626,626|632,653|662,663|666,667|680,692|704,704|707,708|716,716|718,720|723,727|739,739|741,793|811,832|837,838|840,841|845,846|850,854|856,857|866,868|877,888|894,953|968,968 Q:0,12|125,127|130,132|136,140|155,163|186,192|213,213|506,509|512,512|514,527|529,529|531,531|536,538|542,549|602,606|608,608|621,625|627,631|654,661|664,665|668,679|693,703|705,706|709,715|717,717|721,722|728,738|740,740|794,810|833,836|839,839|842,844|847,849|855,855|858,865|869,876|889,893|954,967|969,972 HHHHHHHHHHHHH----------------------------------------------------------------------------------------------------------------TTT??EEE???TTSST--------------THHHHHHHH----------------------HHHHHHS??------------------S?---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEEE??T-TTHHHHHHHHHHHS-T-T?--?EEE???SSHHHHHH----------------------------------------------------HHHHS?S????????????SEEEE?TTHHH----------------------HTHHHHHT--SE--EEEEEETTGGGG---?--------?SSSHHHHHHTT-SE--EEEEEEE?S???SS----?SHHHHHHHHHH?S????---------?????????------------------------------?TTHHHHHHHHHHHTTGG----------------------GEEE??G--GGG--TTT-----S??EEEEEEEE???HHHHHHHH------------HHHHH?????????----------------------------------------------?????THHHHHHHHHHHHH?GGGS 3MWJ|A PF00177.16_Ribosomal_S7_seed 166 267 !Q:0,24|28,29|31,39|49,70|73,73|89,100|103,106|108,108|110,110|112,115|117,133|136,140|150,151|157,171|178,179|181,181|185,187|189,189|206,209|211,217|219,220|223,224|239,239|242,244|258,260|264,266 Q:25,27|30,30|40,48|71,72|74,88|101,102|107,107|109,109|111,111|116,116|134,135|141,149|152,156|172,177|180,180|182,184|188,188|190,205|210,210|218,218|221,222|225,238|240,241|245,257|261,263 -??---?-??????--????----?TTT??H---------HHHHHHHHH??--------------------TT?HHHHHHHHHHHHHHH------------HH----H-H?S---?H-----------------HH-----HHHHHHHHH??SEEEE-------??------EETTEE??E-EEE?-?H-HHHHHHHHHHHHHHHH----H-------S?-SS--SHHHHHHHHHHHHH-TT--?SHHHHHHHHHHHH---HHH-?? 3KIX|g PF00178.17_Ets_seed 15 92 !Q:0,2|13,15|25,25|27,27|34,34|36,37|52,53|56,57|77,79|89,89|91,91 Q:3,12|16,24|26,26|28,33|35,35|38,51|54,55|58,76|80,88|90,90 ???HHHHHHHHHT?--GGGTTTSEE?S-STTEEE?S--SHHHHHHHHHHHTT-?TT??HHHHHHHHHHTTTTTSEEE?--TTSTTEEEE?S? 2STW|A PF00179.21_UQ_con_seed 71 222 !Q:7,12|18,19|29,32|34,37|49,51|59,59|67,68|74,74|76,77|83,84|86,111|115,116|122,130|134,145|148,157|159,159|161,162|169,169|176,181|184,186|190,190|192,192|197,199|205,206|209,211 Q:0,6|13,17|20,28|33,33|38,48|52,58|60,66|69,73|75,75|78,82|85,85|112,114|117,121|131,133|146,147|158,158|160,160|163,168|170,175|182,183|187,189|191,191|193,196|200,204|207,208|212,221 HHHHHHH------HHHHH??TTEEEEEEE----T----TEEEEEEEEEE??-TTSTTTT?EEEEEEE??TTTTS-S??EEEES--S----------------------????TTB?-TTSBB------??-GGG????????????SS??------??T-T??HHHHHH-HHHHHH------HS?-?GGG?S?HHHH---HHHHH?-HH---HHHHHHHHHH 2BEP|A PF00180.15_Iso_dh_seed 23 462 !Q:30,35|40,42|52,53|57,57|68,68|76,78|83,87|90,91|97,99|109,109|119,121|131,131|138,139|147,147|152,181|184,187|201,201|217,221|230,230|234,234|239,242|254,283|285,285|305,305|307,307|310,310|312,313|318,318|335,336|340,340|348,354|357,357|365,367|375,381|383,383|400,401|406,411|425,430|432,433|439,439|442,451|453,453 Q:0,29|36,39|43,51|54,56|58,67|69,75|79,82|88,89|92,96|100,108|110,118|122,130|132,137|140,146|148,151|182,183|188,200|202,216|222,229|231,233|235,238|243,253|284,284|286,304|306,306|308,309|311,311|314,317|319,334|337,339|341,347|355,356|358,364|368,374|382,382|384,399|402,405|412,424|431,431|434,438|440,441|452,452|454,461 EEEEEEESTTHHHHHHHHHHHHHHHHHHHS---???EEEE???THHHHHSSS--SSS?HHHHHHHHTS-SEEEEEE???STTT-----SS??SSSSS?-?HHHHHHHTT-EEEEEEEEE??-GGGTTSSSB?HHHHSS-?EEEEEEE?SSBS??????????--------------------TT---?SEEEEEEEEEHHH-HHHHHHHHHHHHHTT-----TSEEEEEE?TTT?HHHH----HHHHHHHHHHT------------------------------T?TTSEEEEEEHHHHHHHHHH?G-GG?S--EEEE?HHHHHHHHHHHHHHHS?-TTT?EEEEEET-------TS?EEEEESS???TTTTTSS?------S?THHHHHHHHHHHHHHH??HHHH------HHHHHHHHHHHHH------T??BTTTS?SS-------???B?HHHHHHHH 1XAA|A PF00181.18_Ribosomal_L2_seed 50 94 !Q:0,0|5,5|8,9|14,21|23,26|28,29|35,41|50,51|57,57|66,68|70,70|73,77|81,81|85,86|89,89 Q:1,4|6,7|10,13|22,22|27,27|30,34|42,49|52,56|58,65|69,69|71,72|78,80|82,84|87,88|90,93 ?SSSS-SS??STTB??????-?B????S??GGGBS------?EEEEEEEE??TTSSS?EEEEEETT---S?EE-----EEE?BTT??TT?EEEB 2ZJQ|A PF00182.14_Glyco_hydro_19_seed 17 239 !Q:2,2|24,25|41,41|43,43|45,45|65,68|71,71|74,74|78,78|81,82|85,86|88,98|102,104|107,111|118,118|129,130|135,135|139,139|146,146|160,162|165,165|167,168|176,180|188,189|209,211|230,233|235,238 Q:0,1|3,23|26,40|42,42|44,44|46,64|69,70|72,73|75,77|79,80|83,84|87,87|99,101|105,106|112,117|119,128|131,134|136,138|140,145|147,159|163,164|166,166|169,175|181,187|190,208|212,229|234,234 TS?HHHHHHHTTTTTSTTSTTTTT??HHHHHHHHTTSTTTT?S-S?HHHHHHHHHHHHHHHHHHT????TT?TT?GGG?TT??SB??S--?????????SSS???TT?????BTTTTB?SHHHHHHHHH--HHTS?TTT?TTHHHH?HHHHHHHHHHHHH???TT-S??HHHHHTT?????HHHHHTT??SSHHHHHHHHHHHHHSSSS-??HHHHHHHHHHHHHHHHHT????S???? 1WVU|A PF00183.13_HSP90_seed 11 573 !Q:3,3|18,18|21,21|25,93|95,102|107,107|111,112|126,127|129,132|141,141|145,145|153,153|156,171|184,184|190,190|196,196|205,208|214,216|240,261|263,263|285,285|296,297|303,303|307,307|309,309|318,318|321,322|329,329|331,331|338,338|349,350|355,355|368,368|376,376|378,383|385,385|411,411|414,414|417,417|419,419|422,423|426,426|430,430|435,436|440,441|451,469|474,474|477,477|490,491|494,494|514,516|534,572 Q:0,2|4,17|19,20|22,24|94,94|103,106|108,110|113,125|128,128|133,140|142,144|146,152|154,155|172,183|185,189|191,195|197,204|209,213|217,239|262,262|264,284|286,295|298,302|304,306|308,308|310,317|319,320|323,328|330,330|332,337|339,348|351,354|356,367|369,375|377,377|384,384|386,410|412,413|415,416|418,418|420,421|424,425|427,429|431,434|437,439|442,450|470,473|475,476|478,489|492,493|495,513|517,533 GGG?HHHHHHHHHHHSTT?SS?EEE???????????????????????????????-----??--????????????---??????????????B????????TTSS?GGG??TTTHHHHHHHHTT??S?--?SEEEEEEE?SSS?EEEEEEE?SS?????????--?????SEEEETTEEEEE?STTTS?GGGTT?EEEEEESS????BTTTB???HHHHHHHHHHHHHHHHHHHHHHH----------------------S?SHHHHHHHHHHHHHHHHHHHH?SSSHHHHHTT??BEESS?TTS?B?STTHHHHS?TT??EEEEEE?S?STTTTT?GGGHHHHTTT??EEEE?SHHHHHHHGGGS?BTTBEEE?S???-??S?SSTTSSTTHHHHHGGGHHHHHHHHH-TT?SS?S?EE??SS?SSS?EEEE??TTS??HHHHHHHTT????---????????????EEEE?TT?HHHHHHHHHHHT??SS?SSSSTTHHHHHHHHHHHTT???SSTTHHHHHHHHTSSSS??------------------------------------- 1UYH|A PF00184.12_Hormone_5_seed 36 98 !Q:0,3|10,10|13,17|30,35|53,55|58,58|60,63|70,75|87,87|90,90|94,94|97,97 Q:4,9|11,12|18,29|36,52|56,57|59,59|64,69|76,86|88,89|91,93|95,96 ????EESGGG?EE-----EEETTEEEETTT------EEEESSGGGGGGGGGGG?--SS?B??-?SSEETT------TEEEEETTEEE?SS?EEE?TT? 2HNW|A PF00185.19_OTCace_seed 123 276 !Q:2,3|10,20|28,30|36,36|39,40|42,42|47,48|51,63|78,78|80,82|84,85|88,90|92,94|97,97|103,109|115,117|122,142|146,158|167,167|169,169|171,171|177,178|180,180|182,182|184,184|186,189|194,194|196,204|206,210|212,235|239,239|245,249|251,251|254,254|256,256 Q:0,1|4,9|21,27|31,35|37,38|41,41|43,46|49,50|64,77|79,79|83,83|86,87|91,91|95,96|98,102|110,114|118,121|143,145|159,166|168,168|170,170|172,176|179,179|181,181|183,183|185,185|190,193|195,195|205,205|211,211|236,238|240,244|250,250|252,253|255,255|257,275 TT?-EEEEES------?-?-?HHHHHHH---HHHHH-HT?-E-EEEE??TT--???-------?HHHHHHHHHHHHHT-T--?B??EE---S--?HH-HHTTT------?SEEEE???SSTT?-------------------?STT?------------THHHHHGG-G?B?HHHHT--T-S?T-T---?EEEE?S???------B-----T------------------------TTB?HHHHT-----S-TT-B?HHHHHHHHHHHHHHHHHHH 3TXX|A PF00186.14_DHFR_1_seed 89 214 !Q:0,0|11,11|19,19|22,23|33,34|52,57|59,62|71,72|74,74|77,85|87,87|89,92|94,95|98,98|105,110|115,118|120,127|129,129|132,132|136,136|146,147|149,153|162,163|165,170|174,179|181,181|192,195|199,201|203,203|205,205 Q:1,10|12,18|20,21|24,32|35,51|58,58|63,70|73,73|75,76|86,86|88,88|93,93|96,97|99,104|111,114|119,119|128,128|130,131|133,135|137,145|148,148|154,161|164,164|171,173|180,180|182,191|196,198|202,202|204,204|206,213 ?EEEEEEEETT?EEEBTTB?SS??HHHHHHHHH--HHTTSEEEEEHHHHHHH-?----S--??TTSEEEEE?-S?TT--???----T-T---?E--EE?SHHHHH------HHHH----T??------S?EE-EEE?HHHHHHHGG--G??---EEEEEEES--S??-?-?SEE??-???T-TTEEEEEEEE??-?SSS---S?S?EEEEEEEE 5DFR|A PF00187.14_Chitin_bind_1_seed 18 43 !Q:0,2|10,12|16,16|19,19|23,23|36,39|42,42 Q:3,9|13,15|17,18|20,22|24,35|40,41 -??SSGGGTS???GGG?EE?TTS?EESSHHHHSGGG???-BS? 1EHD|A PF00188.21_CAP_seed 98 242 !Q:8,12|19,27|31,35|39,43|45,47|49,49|52,52|64,66|68,69|71,96|100,101|114,121|126,140|151,152|155,165|167,167|172,172|174,181|185,194|202,202|205,206|221,232 Q:0,7|13,18|28,30|36,38|44,44|48,48|50,51|53,63|67,67|70,70|97,99|102,113|122,125|141,150|153,154|166,166|168,171|173,173|182,184|195,201|203,204|207,220|233,241 HHHHHHHH-----HHHHTT???-----?STT?????BSS???-?E---E?HH-HHHHHHHHHTT???S??S?----------------------???SSS??EEEEEEEEESSS----????HHHH---------------HHHHHGGGGG??TT-----------S?GGGS?H--------HHH----------HHHHHHT?TT??EEEEEEEEEEETTE------------EEEEEEEEE 4AIW|A PF00189.15_Ribosomal_S3_C_seed 124 138 !Q:2,11|19,29|32,34|42,47|51,54|56,56|60,62|64,64|67,68|70,70|72,76|79,83|86,93|96,103|105,109|112,112|116,117|123,124|126,126|131,132 Q:0,1|12,18|30,31|35,41|48,50|55,55|57,59|63,63|65,66|69,69|71,71|77,78|84,85|94,95|104,104|110,111|113,115|118,122|125,125|127,130|133,137 HH----------HHHHTTT--------?-?HH---HHHHHHH------HGG----G-TSS-?-S?EE??B?S??---SS----?SS?????--?EE--------S??--?TT?GGG??EEEEE??B?SSSB??EEEEE 3KIX|c PF00190.17_Cupin_1_seed 225 262 !Q:0,2|4,5|7,12|21,23|26,27|29,29|31,33|49,49|59,61|64,64|72,72|80,80|83,86|89,176|180,180|182,184|196,196|199,199|205,206|208,208|211,211|225,243|245,245|247,252|258,261 Q:3,3|6,6|13,20|24,25|28,28|30,30|34,48|50,58|62,63|65,71|73,79|81,82|87,88|177,179|181,181|185,195|197,198|200,204|207,207|209,210|212,224|244,244|246,246|253,257 ???B??S?----?EEETTEEE---EE??S?S---HHHHHHTEEEEEEEE?TTEEEEEEE?--SS?EEEEEEE?EEEEEEE?TT????EE???????????????---------???????????????????-??????????????????---???????????????????????EES?E---EEEETTEEEEE?TT?EEEEE??S-SS?EEEEEEEETTSTT??-----------------S?S--????EESSS???? 3KGL|A PF00191.15_Annexin_seed 177 72 !Q:4,4|15,19|30,31|48,48|50,50|57,57|60,61 Q:0,3|5,14|20,29|32,47|49,49|51,56|58,59|62,71 HHHH-HHHHHHSSSS---??HHHHHHHHHH??HHHHHHHHHHHHHHHS-S?HHHHHH-HH??HHHHHHHHHH 1BO9|A PF00193.12_Xlink_seed 12 105 !Q:0,1|6,6|13,13|15,15|28,28|31,32|43,43|45,48|50,50|53,53|64,77|83,89|92,92|94,94|97,98 Q:2,5|7,12|14,14|16,27|29,30|33,42|44,44|49,49|51,52|54,63|78,82|90,91|93,93|95,96|99,104 -?EEEE?BTTBSS?B?HHHHHHHHHHTT?EE??HHHHHHHHHT-T????S?EE?GGGEEEEEES??????????---?EEEEE-------EE?S?TT??BEEEEE 1POZ|A PF00194.16_Carb_anhydrase_seed 14 286 !Q:0,1|11,18|23,23|28,32|36,36|38,39|42,42|49,49|52,52|59,59|62,63|66,67|72,72|81,82|86,86|94,94|96,96|99,99|110,112|117,119|127,128|139,140|167,168|170,171|185,185|189,189|193,194|196,197|202,203|205,210|217,218|223,224|226,226|235,235|239,239|249,249|253,253|257,259|261,276|279,281|285,285 Q:2,10|19,22|24,27|33,35|37,37|40,41|43,48|50,51|53,58|60,61|64,65|68,71|73,80|83,85|87,93|95,95|97,98|100,109|113,116|120,126|129,138|141,166|169,169|172,184|186,188|190,192|195,195|198,201|204,204|211,216|219,222|225,225|227,234|236,238|240,248|250,252|254,256|260,260|277,278|282,284 ??SSTTTSGGG--------HHHH?GGGG-----SSS?S??EE?TTTSEE?TT?EEEEEE?TT??EE--EEEE?SSSEEEEE??SSS?SEEEEET?S-SE-EEEEEEEEEE?--SSTT???SSEETTB??SEEEEEEEEE--GGGSSHHHHTTSTTSEEEEEEEEEES--S??GGGHHHHHHGGGG?STT?EEE??S??GGGG??S---???EEEEEE??SSTT??S?EEEEEESS?EEE?HHHHHHHTT?BSS?TTS???B-----???????????TT???EES? 4G7A|A PF00195.14_Chal_sti_synt_N_seed 21 231 !Q:0,1|11,12|14,15|24,25|27,27|44,44|47,47|62,64|68,68|70,71|78,78|86,86|88,89|117,117|119,119|123,124|133,135|138,138|149,150|153,153|161,162|183,183|192,192|197,201|204,207|218,219|230,230 Q:2,10|13,13|16,23|26,26|28,43|45,46|48,61|65,67|69,69|72,77|79,85|87,87|90,116|118,118|120,122|125,132|136,137|139,148|151,152|154,160|163,182|184,191|193,196|202,203|208,217|220,229 ??HHHHHHHHS??S??EEEEEEEE??S?EEESTTHHHHHHHHTT?TT?HHHHHHHHHHHHHS???EEE?S??HHHHHT?HHHHSSS?S-?HHHHHHHHHHHHHHHHHHHHHHHHHHH?S?GGG??EEEEEESS???SS?HHHHHHHHHT??TT?EEEEEES??TTHHHHHHHHHHHHHHTSTT?EEEEEEEE?GGGT?????TT?---HHHHHHHHHB??EEEEEEEESS? 3OIT|A PF00196.14_GerE_seed 30 58 !Q:4,4|18,19|30,30|47,48 Q:0,3|5,17|20,29|31,46|49,57 HHHH?HHHHHHHHHHTTT??HHHHHHHTTS?HHHHHHHHHHHHHHTT??SHHHHHHHH 3CLO|A PF00197.13_Kunitz_legume_seed 17 208 !Q:1,1|3,3|7,7|9,9|24,31|36,37|40,40|43,44|49,49|51,51|54,61|66,66|69,72|75,75|79,80|86,91|97,103|105,105|109,109|111,111|114,114|117,117|121,121|123,124|127,129|131,134|142,153|161,176|184,184|188,189|195,195|198,201 Q:0,0|2,2|4,6|8,8|10,23|32,35|38,39|41,42|45,48|50,50|52,53|62,65|67,68|73,74|76,78|81,85|92,96|104,104|106,108|110,110|112,113|115,116|118,120|122,122|125,126|130,130|135,141|154,160|177,183|185,187|190,194|196,197|202,207 B?B?TTS?B?BTTEEEEEEESSTT???-----EEEE??TT?SS??EEEE?S?TT?---????EEEE?SB--??SB?BTT??BEEEE??????GGGTT??----?B?EEE?S?TT-SS-EEE?S??TT---B?--?EEEEEEE???----?????EEEEEEE?????--------???EEEEEEE?TTT??EEEEE?TT-???EEEEEE 1WBC|A PF00198.18_2-oxoacid_dh_seed 100 302 !Q:3,9|25,25|28,30|34,36|41,41|50,50|52,69|75,76|81,89|105,105|110,111|113,117|121,123|125,125|127,129|132,133|137,137|140,140|142,146|148,150|153,154|162,163|182,185|191,193|195,195|200,200|204,207|209,215|217,217|219,220|226,229|234,234|237,238|242,250|257,261|269,269|274,274|287,287|292,294|300,301 Q:0,2|10,24|26,27|31,33|37,40|42,49|51,51|70,74|77,80|90,104|106,109|112,112|118,120|124,124|126,126|130,131|134,136|138,139|141,141|147,147|151,152|155,161|164,181|186,190|194,194|196,199|201,203|208,208|216,216|218,218|221,225|230,233|235,236|239,241|251,256|262,268|270,273|275,286|288,291|295,299 SSS???????HHHHHHHHHHHHHTT-SS???EEE---EEEE?HHHHHHHH-H------------------THHHH--HHTT-----????SHHHHHHHHHHHHHH?GGGS??B--?--TTS---S?B???SS??EEE?EE?S-----S?--EE??EETTGGG??HHHHHHHHHHHHHHHHTT?-??GGGGS?-?S?EEEE?TTT-?-?S???????T-T??EEEEE???-EEEE-EE-?SSS---------EEEEEE-----EEEEEEE?TTTS?SHHHHHHHHHHH-HHHH--?GGGTT-? 1C4T|A PF00199.14_Catalase_seed 121 506 !Q:1,1|5,5|7,7|9,10|14,14|18,21|24,26|28,31|36,36|49,55|59,59|71,72|74,80|84,86|94,98|108,108|111,112|116,116|120,121|124,125|138,138|141,142|148,150|152,152|154,154|163,164|170,170|174,174|176,179|181,181|186,209|216,216|221,221|231,231|236,237|244,244|247,248|250,250|255,256|260,260|263,265|276,278|280,281|288,288|293,293|306,306|310,312|322,322|329,333|335,335|337,337|340,340|343,346|351,351|353,359|369,369|371,372|374,375|383,386|389,392|394,400|404,405|407,407|414,414|427,428|439,446|450,454|456,456|458,464|467,479|484,489|491,495|499,499|502,504 Q:0,0|2,4|6,6|8,8|11,13|15,17|22,23|27,27|32,35|37,48|56,58|60,70|73,73|81,83|87,93|99,107|109,110|113,115|117,119|122,123|126,137|139,140|143,147|151,151|153,153|155,162|165,169|171,173|175,175|180,180|182,185|210,215|217,220|222,230|232,235|238,243|245,246|249,249|251,254|257,259|261,262|266,275|279,279|282,287|289,292|294,305|307,309|313,321|323,328|334,334|336,336|338,339|341,342|347,350|352,352|360,368|370,370|373,373|376,382|387,388|393,393|401,403|406,406|408,413|415,426|429,438|447,449|455,455|457,457|465,466|480,483|490,490|496,498|500,501|505,505 B?SSS?B?S-?SSS?EEE----ST---T-?-?BBTT?HHHHHHHHHHTT-??????SSS?SEEEEEEEEEE?-S?-----?TTT???GGGSSTT?----EEEEEEEEE?SS??TTS?SSS--SS??EEEEEEEETTEE-EE??EESSS?-?S?S?GGGHHHHH--HHHSB?TTT?S----B?HHHH------------------------HHHHHH?GGGH-HHHHHHTSG-GGSB--SSSSSS?EE??S?EEEE?-TTS?EE---EEEEEEEETT???B??HHHHHH-HHHH?TTHHHHHHHHHH-HTT???EEEEEEEEE?HHHHHH?----S-S?TT?TT????TTTS?E-------EEEEEEEEE-E??S?-HHHHTTT????TT??-?T-------TEE??S?HHHHHH-HHHHHHHHHHHT?-TTGGGSTTTS-?------TTS?--??S-S---????SS??-----------TTTT-----?S--???SSS?SS???B 1P81|A PF00200.18_Disintegrin_seed 154 107 !Q:0,0|3,3|5,7|9,9|13,20|24,33|37,38|40,42|45,45|47,51|54,54|59,61|63,63|67,70|73,73|77,80|83,86|88,90|93,94|97,97|100,106 Q:1,2|4,4|8,8|10,12|21,23|34,36|39,39|43,44|46,46|52,53|55,58|62,62|64,66|71,72|74,76|81,82|87,87|91,92|95,96|98,99 ?TT?S???S?TTT?--?---?TTB---------?TTT??B?--TT?S?----SS-STTB?--S-SSB--??TT?EEE???-ST----T???EE??SS?SS??????? 2PJG|A PF00201.13_UDPGT_seed 14 515 !Q:0,0|6,8|26,26|40,47|55,58|61,66|80,80|92,96|101,104|106,107|114,114|126,126|133,134|136,136|154,154|157,158|160,160|163,163|165,165|171,171|174,174|180,180|187,189|209,212|214,214|220,220|222,222|225,225|238,238|242,245|250,267|276,278|281,281|287,288|291,294|298,298|311,312|317,318|326,326|335,336|344,346|362,364|376,377|381,383|399,399|403,403|408,409|425,458|463,463|470,484|498,498|513,514 Q:1,5|9,25|27,39|48,54|59,60|67,79|81,91|97,100|105,105|108,113|115,125|127,132|135,135|137,153|155,156|159,159|161,162|164,164|166,170|172,173|175,179|181,186|190,208|213,213|215,219|221,221|223,224|226,237|239,241|246,249|268,275|279,280|282,286|289,290|295,297|299,310|313,316|319,325|327,334|337,343|347,361|365,375|378,380|384,398|400,402|404,407|410,424|459,462|464,469|485,497|499,512 ?EEEEE???STSHHHHHHHHHHHHHH?TSEEEEHHHHHHT????????TTEEEEE????TT??????TTHHHHHHHHHHH-HHHHHHHHHHH-----HHHS????E--EEEETT?TTHHHHHHHHT?EEEEEE?-S?HHHHHHHHTHHHHHHHH?SS??T?TT?B?TTSTT?TT?BGGGS?TTSSSS?--TTSHHHHHHHHHHHHGGGS----S?EEESS?G-GG?HHHHHHHHHHSS?EEE??-?HHHH?????????-------??HHHHHTTS?--TT?EEEEE??SS????HHH-HHHHHHHHHHHT??EEEE??GGGGGGS?TTHHHHHT--TTEEEES???HHHHHTSTTEEEEEE???HHHHHHHHHHT??EEE???STTHHHHHHHHHHTT?EEE?TTSS??HHHHHHHHHHHHHSH----------------------------------HHHH-HHHHHH---------------HHHHHHHHHTSTT?HHHHHHHHHHHHHH?? 3HBJ|A PF00202.16_Aminotran_3_seed 18 412 !Q:11,11|15,16|28,28|31,31|34,34|48,48|50,52|58,58|73,76|78,78|81,81|103,110|115,136|144,147|158,159|167,170|174,181|185,187|192,203|206,206|222,223|228,229|235,235|237,237|239,239|245,245|247,248|264,264|270,270|287,288|292,296|302,303|310,310|312,313|327,329|333,339|341,342|347,347|383,383|389,390|400,401 Q:0,10|12,14|17,27|29,30|32,33|35,47|49,49|53,57|59,72|77,77|79,80|82,102|111,114|137,143|148,157|160,166|171,173|182,184|188,191|204,205|207,221|224,227|230,234|236,236|238,238|240,244|246,246|249,263|265,269|271,286|289,291|297,301|304,309|311,311|314,326|330,332|340,340|343,346|348,382|384,388|391,399|402,411 EEEEEEBTEEE-ETT??EEEESSHHHHT?TT?BT?HHHHHHHHHHTTT?S???TTTEE?HHHHHHHHHHHHHS----S?SS?EEEEEESSHHHHHHHHHHHHH--------HHHT??--------------------EEEEETT????SSHHHHHHSS??TTTTTTS????SSE--------EEE???BGGG------------TB?HHHHHHHHHHHHHHT??GGGE--EEEEE?S-B?TTTTS?B??HHHHHHHHHHHHHHT?EEEEE?TTTTTTTTSSSSGGGG--TTS??---SEEEE?-GGGGTS-S??EEEEEEHHHHTTS--?TTS-------B??SSSS?HHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHH-HHHHT?-TTEEEEEEE--TTEEEEEEBG 2HOY|A PF00203.16_Ribosomal_S19_seed 22 82 !Q:0,0|2,2|5,9|24,28|32,34|36,39|42,42|45,46|51,51|54,54|59,61|64,64|67,68|74,74|77,78 Q:1,1|3,4|10,23|29,31|35,35|40,41|43,44|47,50|52,53|55,58|62,63|65,66|69,73|75,76|79,81 ?S?SS?????HHHHHHHHTTTTTT??-??EEE???S????TT?TT??EEEE?SS?EEEE???SS?SS??STTTS?SS??SSS 3KIX|s PF00204.20_DNA_gyraseB_seed 99 250 !Q:12,17|19,20|23,29|32,36|44,57|60,63|74,74|76,77|79,83|85,85|92,93|98,98|101,101|124,124|128,133|137,145|158,158|161,164|166,166|169,172|178,179|182,183|188,189|196,197|204,204|209,210|212,212|214,217|233,236|241,242 Q:0,11|18,18|21,22|30,31|37,43|58,59|64,73|75,75|78,78|84,84|86,91|94,97|99,100|102,123|125,127|134,136|146,157|159,160|165,165|167,168|173,177|180,181|184,187|190,195|198,203|205,208|211,211|213,213|218,232|237,240|243,249 HHHHHHHHHHHT------S-?BS-------SS?---?EEEEEEE--------------TT----EEEEEEEEEB-S--S??---E-EEEEEE--TTEE?TT?BHHHHHHHHHHHHHHHHHHHHT-THH------HHH-?---????HHHHTTTEEEEE-EE----E?SS?--?BSSTT??SB??HHHH--HHHHHH--HHHHHH-HHHH--H?H----HHHHHHHHHHHHHHH----HHHH--HHHHHTT 1ZXN|A PF00205.17_TPP_enzyme_M_seed 309 275 !Q:10,10|12,14|17,18|23,23|28,30|32,34|46,49|51,51|54,54|58,59|64,65|67,76|79,94|98,100|103,103|105,105|109,109|111,116|124,124|127,129|137,144|146,146|149,154|157,158|162,162|168,178|180,188|190,191|195,195|197,218|220,220|222,230|238,251|253,253|259,259|262,268 Q:0,9|11,11|15,16|19,22|24,27|31,31|35,45|50,50|52,53|55,57|60,63|66,66|77,78|95,97|101,102|104,104|106,108|110,110|117,123|125,126|130,136|145,145|147,148|155,156|159,161|163,167|179,179|189,189|192,194|196,196|219,219|221,221|231,237|252,252|254,258|260,261|269,274 HHHHHHHHHH?S---SE--EEEE?GGGT---T--?HHHHHHHHHHH-???E-EE?TTT--TTSS?-T----------TS----------------TTE---EE-E?STT-S-----?HHHHHHH-HH--?SEEEEES-??---??H-HH------HS--SGG-GTTTT--------?--E---------E--EEE-E----------------------S?G---------GGTTSSS---------?---?S-EEEES?HH-------HHHHHH 1PVD|A PF00206.15_Lyase_1_seed 18 344 !Q:5,5|8,11|21,23|25,26|28,28|30,31|56,56|73,73|80,82|87,87|90,90|111,112|117,117|120,120|129,130|172,172|211,211|218,218|221,221|227,227|231,231|233,233|245,246|250,250|252,253|256,256|258,258|265,266|287,287|296,297|302,304|307,310|312,316|319,319|322,325|331,333 Q:0,4|6,7|12,20|24,24|27,27|29,29|32,55|57,72|74,79|83,86|88,89|91,110|113,116|118,119|121,128|131,171|173,210|212,217|219,220|222,226|228,230|232,232|234,244|247,249|251,251|254,255|257,257|259,264|267,286|288,295|298,301|305,306|311,311|317,318|320,321|326,330|334,343 EEEEE?TT????HHHHHHTTT???S--S?B??HHHHHHHHHHHHHHHHHHHHHTSS?HHHHHHHHHHHHHHHT-TSSGGG???BSSS?TT?HHHHHHHHHHHHHHHHHHTT??SSTT?SS?IIIIITTT??HHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHTTT?EEEEEETTEEEEEEEHHHHHHHHHHHHHHHHHHHHTTH-HHHTEE?TT?TTTSS?TTS?T-THHHHHHHHHH--HHH?S??EE?S?HHHHHH??HHHHHHHHHHHHHHHHHHHH-HHHHHHHT??SSSS???EE????S?--??SS?TT????HHHHH---HHHHHHHHHH 1FUQ|A PF00207.17_A2M_seed 131 136 !Q:8,8|10,17|19,19|21,23|26,27|29,32|35,36|38,39|52,76|84,84|86,86|89,90|92,92|100,101|109,109|118,118|120,121|125,127|130,130 Q:0,7|9,9|18,18|20,20|24,25|28,28|33,34|37,37|40,51|77,83|85,85|87,88|91,91|93,99|102,108|110,117|119,119|122,124|128,129|131,135 EEEEEEEE?B--------T-T---EE??B????SS??S-?EEEEEEEEETTT-------------------------EEEEEEE-E-EE??B?SEEEEEE??SEEESSS?EEEEEEEE-E?-SSS?--EE-EEEEE 4FXG|B PF00208.16_ELFV_dehydrog_seed 124 348 !Q:1,3|25,25|28,33|37,37|44,45|60,60|62,62|65,65|69,69|76,80|83,88|99,99|103,107|115,121|123,127|130,130|133,135|137,155|158,164|166,174|181,181|186,186|188,188|197,201|204,208|210,211|215,216|220,220|222,223|229,229|236,246|250,250|274,276|288,298|311,311|313,314|318,326|347,347 Q:0,0|4,24|26,27|34,36|38,43|46,59|61,61|63,64|66,68|70,75|81,82|89,98|100,102|108,114|122,122|128,129|131,132|136,136|156,157|165,165|175,180|182,185|187,187|189,196|202,203|209,209|212,214|217,219|221,221|224,228|230,235|247,249|251,273|277,287|299,310|312,312|315,317|327,346 T??-TTSHHHHHHHHHHHHHHHHTT-TT??----STT?EEEEEE?-SHHHHHHHHHHHHT-T?EE?EEE?SSEEEE----?SS???---HHHHHHHHHH-HHH???-?HHHHHHH-------H-???-EE-ET-??T-------------------TS-------S-------??SEEEEE-SSTT?B?HHHHHHHH-----HH-----T??EEE??SSS?B?-HHHHH-HHHHTT----------?EEE?HHHHTHHHHHHHHHHHHHHHTTS???HHHHHHHHHHH-----------HHHHHHHHHHTS?S--SSS?-------?HHHHHHHHHHHHHHHHHHHT? 1C1D|A PF00209.13_SNF_seed 15 638 !Q:0,3|18,18|65,65|67,67|76,76|112,112|116,116|120,120|122,128|132,133|137,137|141,142|147,173|186,186|190,199|203,205|208,208|270,272|278,278|294,294|308,308|311,312|347,392|397,420|473,473|479,482|503,503|521,521|555,557|583,588|593,593|596,607|610,610 Q:4,17|19,64|66,66|68,75|77,111|113,115|117,119|121,121|129,131|134,136|138,140|143,146|174,185|187,189|200,202|206,207|209,269|273,277|279,293|295,307|309,310|313,346|393,396|421,472|474,478|483,502|504,520|522,554|558,582|589,592|594,595|608,609|611,637 ????SSHHHHHHHHHHHH?STHHHHTHHHHHHHTTGGGGHHHHHHHHHHTHHHHHHHHHHHHHHH?S?HHHHHHHH?STTTHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHT?SSS?TTS?S------?STT??TTE-ESS??TTSE---------------------------EHHHHHHHHTTT?GGG--------??SSS???SB?HHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHTTHHHHHHHHHHHHHHHSTTHHHHHHHHH???GGGGG?HHHHHHHHHHHHHHH?TTSSHHHHHHHTS?TT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS???-------------------------------------------HHHH???---------------------THHHHHTHHHHHHTTSTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?HHHHS---?HHHHHHHHHHHHHHHHTTTT-BTTHHHHHHHHHHHTST-THHHHHHHHHHHHHHHTTTHHHHHHHHHHHHSS???HHHHHHHHTHHHHHHHHHHHHHHHT?--???EETT-EE----------??HH-HHHHHHHHHHHHHTHHHHHHHHHHTTS 3MPQ|A PF00210.19_Ferritin_seed 243 218 !Q:11,13|29,30|34,34|50,50|65,102|104,136|138,138|167,170|173,178|180,182|190,190|197,197|213,214 Q:0,10|14,28|31,33|35,49|51,64|103,103|137,137|139,166|171,172|179,179|183,189|191,196|198,212|215,217 HHHHHHHHHHH---HHHHHHHHHHHHHHH--HTT?HHHHHHHHHHHHHHH-HHHHHHHHHHHHTT--------?-----??-------????-----------B?????--------------------------??S-SHHHHHHHHHHHHHHHHHHHHHHHHHHH----HT------T--?HHHHHHH-HHHHHH-HHHHHHHHHHHHHHH--HHH 3SH6|A PF00211.15_Guanylate_cyc_seed 21 276 !Q:0,2|26,30|50,50|54,54|57,57|61,63|66,66|75,94|96,97|116,116|119,119|124,155|158,159|175,177|181,181|201,201|208,209|223,224|233,233|237,238|240,247|249,265|268,268 Q:3,25|31,49|51,53|55,56|58,60|64,65|67,74|95,95|98,115|117,118|120,123|156,157|160,174|178,180|182,200|202,207|210,222|225,232|234,236|239,239|248,248|266,267|269,275 ???EEEEEEEEEEEEETTHHHHHHHS?????HHHHHHHHHHHHHHHHHHH?TTT?TT?EEE???TT?EEEEESSS--------------------S??TTHHHHHHHHHHHHHHHH-TT?EETT--------------------------------EE??EEEEEEEEEEEEEEE?--SSS?EEEEESHHHHHHHHHHHTS?TTSEEE--EHHHHHHTTSTTT??TTEEEEEE-EEE??T--------T----?------------SS?EEEEEEE 1YBT|A PF00212.13_ANP_seed 39 36 !Q:0,0|3,5|7,8|10,16|21,22|26,28|31,35 Q:1,2|6,6|9,9|17,20|23,25|29,30 ?SS???S??S-------SSSS??TTS???SS????? 1Q01|A PF00213.13_OSCP_seed 192 235 !Q:2,2|13,13|15,15|17,23|26,33|38,40|48,49|64,64|72,75|83,83|88,110|113,116|118,122|136,136|150,150|157,160|162,162|166,166|168,171|182,183|190,218|231,231 Q:0,1|3,12|14,14|16,16|24,25|34,37|41,47|50,63|65,71|76,82|84,87|111,112|117,117|123,135|137,149|151,156|161,161|163,165|167,167|172,181|184,189|219,230|232,234 SS?TTHHHHHHHT-T-T-------TT--?-----HHHH---HHHHHHH--HHHSSSTTSHHHHT?TTTTTST----TTTTTTH-HHHT-----------------------TT?--?S-----SSSHHHHHHHHTT?GGGHHHHHHHHHH-HHTTTS????B?SSS?B????SSSTTTTTTT--TSSTTT??????????????????????---????TTTTTTTTTTTT?TTT 2JMX|A PF00214.14_Calc_CGRP_IAPP_seed 13 154 !Q:0,100|107,109|128,131|134,135|140,153 Q:101,106|110,127|132,133|136,139 ----------------------------------------------------------------------------------------------???????SSSSSS???SSSSSSHHHHHHHHTTSS????SS??HHHH???????------- 3G7W|A PF00215.19_OMPdecase_seed 87 401 !Q:0,1|7,8|12,25|30,32|39,39|41,41|44,44|58,65|76,76|78,81|89,89|91,91|101,104|111,111|121,122|138,184|186,186|188,236|238,238|244,244|246,246|249,250|257,257|260,263|265,265|280,291|294,294|299,300|305,319|326,329|331,331|340,365|367,368|377,377|383,383|389,389|391,392 Q:2,6|9,11|26,29|33,38|40,40|42,43|45,57|66,75|77,77|82,88|90,90|92,100|105,110|112,120|123,137|185,185|187,187|237,237|239,243|245,245|247,248|251,256|258,259|264,264|266,279|292,293|295,298|301,304|320,325|330,330|332,339|366,366|369,376|378,382|384,388|390,390|393,400 ??EEEEE??SSH--------------HHHH---HHHTTS?T-TS?EEEEEHHHHHHHH--------HHHHHHHHHT-T--??EEEEEEE?S?HHHHHHHHH----HHHHHT?SEEEEEGGG?-HHHHHHHHHTTGGGG-----------------------------------------------G-G-------------------------------------------------S?EEEEE?S?TT??HHHHHH-TT?--?S?HHHHHHHHHHHHHH------------TT?SEEE??HHHH---------------HHHHHH----H?TTSEEEEE????------------??????????S??HHHHHHHT?SEEEE?HHHHT?S-?HHHHHHHH 2QCD|A PF00216.16_Bac_DNA_binding_seed 158 132 !Q:0,0|10,18|20,24|28,39|59,60|64,74|78,78|83,94|98,98|102,102|105,105|109,119|122,122|131,131 Q:1,9|19,19|25,27|40,58|61,63|75,77|79,82|95,97|99,101|103,104|106,108|120,121|123,130 ?BSHHHHHHH---------H-----HHH------?-?--?HHHHHHHHHHHHHHHHHHH--HHT??---?----?BTT-TBEE????---????-EEE?SSS-SS-EEE?---???????EE?TTHHHHHT? 1B8Z|A PF00217.14_ATP-gua_Ptrans_seed 115 285 !Q:0,2|4,4|17,17|22,23|27,29|47,53|57,58|67,73|85,99|115,115|144,146|148,148|167,169|175,177|179,179|187,188|194,194|197,198|206,206|213,216|219,219|233,236|241,241|245,247|255,257|261,261|270,270 Q:3,3|5,16|18,21|24,26|30,46|54,56|59,66|74,84|100,114|116,143|147,147|149,166|170,174|178,178|180,186|189,193|195,196|199,205|207,212|217,218|220,232|237,240|242,244|248,254|258,260|262,269|271,284 ???T-TTEEEEEEEEEE?BTTS??TTT?-?HHHHHHHHHHHHHHHTT?-----?GGG?-EEEEEGGG-----??HHHHHHHHHTT------?????-???HHHHTTTTTTTTTTT?EEEEETTSSEEEEESSSSSEEEEEEEES---S?HHHHHHHHHHHHHHHHHH---HHHTT-??B?EETTTEE??SSGGG?BT??EEEEEEE?HHHHTS----TT-HHHHHHHHTEEEE????STTT-TTT---TEEEEEE???SSS?HHHHHHHH-HHHHHHHHHHHHHH 3DRE|A PF00218.16_IGPS_seed 20 279 !Q:19,19|21,22|29,37|39,39|45,45|47,50|53,53|60,60|70,70|73,74|86,87|94,95|100,102|113,114|116,116|120,127|130,132|145,145|155,156|160,161|174,174|181,181|191,191|195,195|211,211|221,223|225,228|230,230|233,233|241,244|255,256|262,262|268,268|270,270 Q:0,18|20,20|23,28|38,38|40,44|46,46|51,52|54,59|61,69|71,72|75,85|88,93|96,99|103,112|115,115|117,119|128,129|133,144|146,154|157,159|162,173|175,180|182,190|192,194|196,210|212,220|224,224|229,229|231,232|234,240|245,254|257,261|263,267|269,269|271,278 HHHHHHHHHHHHHHHHHHS?G--GGTGGG?----????S?HHHHH?S----SS?EEEEEE?SEETTTEES?SS??HHHHHHHHTTT-?SEEEEE??STTT???TTHHHHHHHH??S?EEE--------ES???SHHHHHHHHHTT?SEEEEETTT??HHH--HHHHHHHHHHTT?EEEEEE?SHHHHHHHH-HTT?SEEEEESEETTTTEE?THHHHHHHH---H----H?TT-SEEEEES????HHHHHHHTTT-?SEEEE?HHHHT?S?HHHHHHHH 4A2S|A PF00219.13_IGFBP_seed 54 93 !Q:0,7|9,9|16,35|37,38|44,46|50,51|55,56|58,58|60,67|73,78|82,83|85,87 Q:8,8|10,15|36,36|39,43|47,49|52,54|57,57|59,59|68,72|79,81|84,84|88,92 ??-----?B?STTTSS?----------------???S??SSEEE?--STT??SEE--E?B?-------TTSEE-----?SSS??B--?TTEEE 2DSQ|A PF00221.14_Lyase_aromatic_seed 143 710 !Q:3,4|7,10|19,22|24,24|26,30|35,37|53,53|60,63|69,69|76,76|78,89|93,95|108,110|114,157|159,160|179,184|186,188|199,199|207,208|212,214|217,217|230,230|232,232|235,235|239,239|242,242|244,250|253,270|272,276|280,280|287,296|341,342|347,347|354,354|356,358|373,373|375,380|382,386|395,400|403,403|405,431|461,466|474,484|486,489|491,505|507,507|509,515|517,521|524,525|555,555|562,564|568,568|571,576|578,581|584,586|608,608|612,615|618,618|623,629|640,640|666,682|684,684|698,701|703,709 Q:0,2|5,6|11,18|23,23|25,25|31,34|38,52|54,59|64,68|70,75|77,77|90,92|96,107|111,113|158,158|161,178|185,185|189,198|200,206|209,211|215,216|218,229|231,231|233,234|236,238|240,241|243,243|251,252|271,271|277,279|281,286|297,340|343,346|348,353|355,355|359,372|374,374|381,381|387,394|401,402|404,404|432,460|467,473|485,485|490,490|506,506|508,508|516,516|522,523|526,554|556,561|565,567|569,570|577,577|582,583|587,607|609,611|616,617|619,622|630,639|641,665|683,683|685,697|702,702 EEE-?TT?-??HHHHHHHH----H-S?---?EEEE?--GGGHHHHHHHHHHHH-HHHHTT-???TTTTB?SGGGTT?B?--?--------HHH---HHHHHHHHHHHH???EEE--------------------------------------------E??HHHHHHHHHHHHHHHTTS-----?S???HHHHHHHHHH-HHHTEEE??EEE???SS?HHHHHHHHHGGG-T?SE-EEE-TT-E-------EE------------------E-----HHH-HHHHTT?????--?-?TTHHHHHHSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??SGGG?HHHHHH-H?-?HHHHHHHHHHHHHH?S?-?---H-----HHHHTTTG------GG-S----------?--------------??HHHHTHHHHHHHHHHHHHHHHHHHHHHHT??--??SSEEETT-----------T----T---------------E-E-------E?--??TT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHH?HHHHSS-?-GGG?SS------T----TT-??TTHHHHHHHHHHHHHHHHHTS?STT????BT-TTTB?--????HHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHTSTT--------?-----???H-HHHHHHHHHHTTS????S--?---? 1GK2|A PF00223.14_PsaA_PsaB_seed 22 926 !Q:1,1|7,12|27,28|30,32|36,36|38,39|73,74|81,81|86,87|90,96|104,109|118,119|123,124|126,126|136,137|161,172|176,176|182,205|207,207|211,218|221,221|259,271|273,274|279,281|288,288|298,298|301,303|305,310|315,315|322,339|342,350|352,356|362,365|386,386|388,389|392,392|394,394|397,397|405,408|411,424|439,439|466,467|471,471|474,474|508,511|516,525|533,539|577,577|588,591|602,603|608,615|620,623|626,626|628,629|631,631|633,633|639,643|648,648|654,659|689,690|693,693|700,700|703,705|707,707|709,709|712,713|716,716|749,749|753,777|780,781|788,800|802,802|828,828|833,837|862,862|882,884|887,893|895,899 Q:0,0|2,6|13,26|29,29|33,35|37,37|40,72|75,80|82,85|88,89|97,103|110,117|120,122|125,125|127,135|138,160|173,175|177,181|206,206|208,210|219,220|222,258|272,272|275,278|282,287|289,297|299,300|304,304|311,314|316,321|340,341|351,351|357,361|366,385|387,387|390,391|393,393|395,396|398,404|409,410|425,438|440,465|468,470|472,473|475,507|512,515|526,532|540,576|578,587|592,601|604,607|616,619|624,625|627,627|630,630|632,632|634,638|644,647|649,653|660,688|691,692|694,699|701,702|706,706|708,708|710,711|714,715|717,748|750,752|778,779|782,787|801,801|803,827|829,832|838,861|863,881|885,886|894,894|900,925 T?GGGTT??----SBTHHHHHHHHTTT?-G---GGT?S-?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS??HHHHHH?TTTS??EE????-??TTGGGGS------EEEETTEE--EEE??S?HHHHHHHHT??SHHHHHHHHHHHHHHHHHHHHHH------------HHH-HHTEE------------------------E?HHH--------HT?HHHHHHHHHHTHHHHHHHHHHHHHHHTHHHHHHHHTT-------------T??STTS-??TTHHHH?HHHHHHSST-TS???S??????TTTT?GGGGTT------------------TS????-----S---??TTTSS??--HHHHHHHHHHHHHHHHHHTT?B??SS-S?SB?HHHHHHH???-SS--------------STTTTTTHHHHHHH?HHHHHHHHHHHHHHHHHHHHHHHHHS??STT?TT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?--?GGGG----------SSSHHHH-------HHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?GGGSBSTTSB????HHHHHHHHHH--HHTB--------TTTB----TT?S--S?S?TTSSS---??EEET-TEEEE??????HHHHHHHHHHHHHHHHHHHHHHHHHHTSS??SS?TTHHHH?SS???S?S?TT??TT?SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?EEE------------------------?TT??EEETTT-------------T?HHHHTTSHHHHHHTTHHHHTHHHHH?TTST-----THHHHHHHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHHHTT???SS-------B?????HHHHHHHHHHHHHHHHHHHHHHHHHH 2WSE|A PF00224.16_PK_seed 13 392 !Q:0,2|9,10|13,29|31,32|35,38|59,59|84,87|93,95|97,97|101,102|104,106|108,109|112,112|115,115|118,118|124,125|129,129|133,134|142,142|145,147|152,153|156,156|173,173|177,178|186,186|189,190|193,193|197,197|200,205|208,208|214,214|223,223|225,226|233,235|252,252|262,262|268,270|273,275|298,298|318,319|333,333|336,337|352,352|364,364|366,366|386,386 Q:3,8|11,12|30,30|33,34|39,58|60,83|88,92|96,96|98,100|103,103|107,107|110,111|113,114|116,117|119,123|126,128|130,132|135,141|143,144|148,151|154,155|157,172|174,176|179,185|187,188|191,192|194,196|198,199|206,207|209,213|215,222|224,224|227,232|236,251|253,261|263,267|271,272|276,297|299,317|320,332|334,335|338,351|353,363|365,365|367,385|387,391 ???SEEEEE??TT-----------------T??HH----HHHHHHHTTEEEEEEETTSS?HHHHHHHHHHHHHHHHTTTTSTTT????EEEEE???S?EEB??B???S?-SS?EE?TT?EEEEE??TTS-SSB??SSEEEBS?TT---HHHH??TT?EEEETTTTEEEEEEEE?SSE--EEEEESS?EE??TT?EEE?TT??????SS?HHHHH-HHHHHHHT-T-?SEEEES???SHHHHHHHHHHHTTTT-TTSEEEEEE?SSHHH---HT---HHHHHHHSSEEEEEHHHHHHHS?TTTHHHHHHHHHHHHHHHT??EEEESSSSGGGGT?SS??HHHHHHHHHHHHHT?SEEEESHHHHT?S?HHHHHHHHHHHHHHHHHTS?HHHHH 3EOE|A PF00225.18_Kinesin_seed 84 630 !Q:2,5|13,14|16,16|21,74|81,82|85,85|89,90|95,95|101,103|106,106|112,114|123,123|133,133|136,137|144,145|158,188|193,193|195,195|211,213|215,316|324,324|340,340|343,373|375,381|383,383|387,387|393,396|402,404|408,408|451,452|457,458|461,477|487,489|493,511|536,573|589,590|592,592|601,602|606,611|627,629 Q:0,1|6,12|15,15|17,20|75,80|83,84|86,88|91,94|96,100|104,105|107,111|115,122|124,132|134,135|138,143|146,157|189,192|194,194|196,210|214,214|317,323|325,339|341,342|374,374|382,382|384,386|388,392|397,401|405,407|409,450|453,456|459,460|478,486|490,492|512,535|574,588|591,591|593,600|603,605|612,626 EE????HHHHHTT??B?EEEE------------------------------------------------------TTEEEE??TT?TTS??EEEE?SEEEE?--SS?TTSSS???HHHHHHHT-HHHHHHHHH-TT??EEEEEE?-STTSSHHHHHTB------------------------------?SSTT?B?HHHHHHHHHHHHHHT???T------------------------------------------------------------------------------------------------------TEEEEEE-EEEEEEETTEEEETT?TT?-----------------------------?S?------B?EEE-ETTTE----EEETT???EEE?SHHHHHHHHHHHHHHHTSGGGGTTTHHHHSEEEEEEEEEEEE??TTTT??EE-----------------EEEEEEEEE???GGG?????---------?????HHHHHHHHHHHHHHHHHHHHHHHT??--------???????------------?????????TTSHHHHHTGGGGSS--S?EEEEEEEE??BST------THHHHHHHHHHHHHH??? 4H1G|A PF00226.26_DnaJ_seed 257 95 !Q:0,0|7,8|10,18|20,21|37,37|41,43|46,68|89,89|95,95 Q:1,6|9,9|19,19|22,36|38,40|44,45|69,88|90,94 ?HHHHHT??T---------T??HHHHHHHHHHHHHHH?TTT???HH-----------------------HHHHHHHHHHHHHHHTSHHH-HHHHH- 1NZ6|A PF00227.21_Proteasome_seed 174 261 !Q:4,6|11,13|21,23|25,25|27,34|36,36|40,40|44,50|55,56|67,67|81,81|85,85|89,89|92,92|94,95|97,99|102,104|119,119|121,122|125,127|129,136|138,138|140,140|149,149|151,151|153,153|155,159|166,168|171,173|178,180|186,186|195,195|201,206|209,212|217,219|229,229|231,232|235,236|238,240|242,247|249,250|254,255 Q:0,3|7,10|14,20|24,24|26,26|35,35|37,39|41,43|51,54|57,66|68,80|82,84|86,88|90,91|93,93|96,96|100,101|105,118|120,120|123,124|128,128|137,137|139,139|141,148|150,150|152,152|154,154|160,165|169,170|174,177|181,185|187,194|196,200|207,208|213,216|220,228|230,230|233,234|237,237|241,241|248,248|251,253|256,260 HHHS?-?EEEE?-?SSEEEEE---E-E?-???---S-TTB?TTT--?--??EEEE--ETTEEEEEEE?SHHHHHHHTTHHH-HHH-HHH-HT-T?-S???HH---HHHHHHHHHHHHTT-S--BS---S?-???---S-E-EEEEEEEE-T-T-E-----EEEEEE--?TT???EEES---EEEES-TTHHHHTT-THHHH?----?TT--??SHHH---HHHHHHHHH-H--HS--S---S----??T--TSE--EEEEE 3TDD|A PF00228.15_Bowman-Birk_leg_seed 55 31 !Q:0,1|9,13|17,18|22,23|28,30 Q:2,8|14,16|19,21|24,27 ??SSEEEES-----SSS??EEE??EEES??? 1BBI|A PF00229.13_TNF_seed 52 170 !Q:0,3|8,9|11,12|14,14|17,17|20,20|24,25|28,29|31,31|44,49|53,54|57,75|84,84|88,92|94,94|103,105|109,111|116,117|119,119|134,134|137,137|143,144|147,149|154,155|157,158|166,166|169,169 Q:4,7|10,10|13,13|15,16|18,19|21,23|26,27|30,30|32,43|50,52|55,56|76,83|85,87|93,93|95,102|106,108|112,115|118,118|120,133|135,136|138,142|145,146|150,153|156,156|159,165|167,168 ????SSST--T??B?TT?EE?SSS--EE??S?EEEEEEEEEEEE------EES??SS---------------?-??EEEEEEEE?SSS----?S?EEEEEEEE-??SSS???SSST--T?EEEEEEEEEEEEEE?TT?EEEEE--ES--?GGGB??S?-SSSSEEE?BB? 2RE9|A PF00230.15_MIP_seed 14 296 !Q:0,5|7,8|29,30|39,77|85,85|100,101|104,108|120,122|161,162|177,180|183,184|208,208|214,215|218,220|242,246|269,270|275,275|296,296 Q:6,6|9,28|31,38|78,84|86,99|102,103|109,119|123,160|163,176|181,182|185,207|209,213|216,217|221,241|247,268|271,274|276,295 ??????H--HHHHHHHHHHHHHHHHHHHH--HHHHHHHS??-------------------------???---------HHHHHHH-HHHHHHHHHHHHHH--HH?????HHHHHHHHHHS???GGGHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHTT??TTSGGGHHHHTTTS????TT??HHHHHHHHHHHHHHHHHHHHHHH?TTSSS??GG---GHHHHHHHHHHHHHHHTHHHH?????HHHHHHHHHHHHHTTTTTHHHH-?SSSS?TTHHHHHHHHHHHHHHHHHH- 3C02|A PF00231.14_ATP-synt_seed 161 458 !Q:0,2|26,26|47,101|104,104|106,114|117,131|134,136|155,155|159,161|163,172|182,183|185,185|187,199|202,204|206,217|219,222|225,226|232,232|243,245|249,250|252,285|287,298|304,311|314,390|436,457 Q:3,25|27,46|102,103|105,105|115,116|132,133|137,154|156,158|162,162|173,181|184,184|186,186|200,201|205,205|218,218|223,224|227,231|233,242|246,248|251,251|286,286|299,303|312,313|391,435 ???SSSSHHHHHHHHHHHHHHHHHHH-HHHHTTSTTTSSSSSSSSTT-?????????---???----?---------------------------????--?SS?S??-----??SS?-------???????TT???THHHHHHHTGGGTTTTSS?TTS---S??---?????SHHHHHHHH--S-S-------------SS?-?S?---------??S???-SS??STTTH-HHHHHHHHHH---SSS--S---------------------------------?S?--????????-SBTTB????????SS?----------------------------------------------?????????????????--???????????TTSSHHHHTTTTTHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTS???????????????-?????? 3OAA|G PF00232.13_Glyco_hydro_1_seed 13 523 !Q:0,0|5,5|8,8|14,15|20,22|28,30|35,39|45,45|53,56|61,61|78,78|85,86|99,101|120,120|130,131|140,140|144,144|169,170|177,177|189,190|194,194|196,197|201,203|207,208|210,210|238,240|243,243|265,265|286,286|289,290|301,310|312,315|323,325|328,329|331,331|345,354|357,360|367,367|374,374|378,378|382,382|384,384|389,389|391,392|408,413|419,422|425,426|430,432|438,439|458,458|462,463|471,471|474,477|482,482|487,488|495,498|507,507|519,522 Q:1,4|6,7|9,13|16,19|23,27|31,34|40,44|46,52|57,60|62,77|79,84|87,98|102,119|121,129|132,139|141,143|145,168|171,176|178,188|191,193|195,195|198,200|204,206|209,209|211,237|241,242|244,264|266,285|287,288|291,300|311,311|316,322|326,327|330,330|332,344|355,356|361,366|368,373|375,377|379,381|383,383|385,388|390,390|393,407|414,418|423,424|427,429|433,437|440,457|459,461|464,470|472,473|478,481|483,486|489,494|499,506|508,518 ?TTSS?SS?EEEEE??HHHH???TTSTT???BHHH-----HHHHH?GGGSTTS??-?SSTT?HHHHHHHHHHHHHHTT?SEEEEE??HHHHSTTSSTTT???HHHHHHHHHHHHHHHHTT?EEEEEEESS??BHHHHHHH?GGG?TTSSHHHHHHHHHHHHHHHHHTTT??EEEEEE?HHHHHHHHHTS??STT?B??TTS--?SSB??S?TTTHHHHHHHHHHHHHHHHHHHHHHHT?-?TT?EEEEEEEEEEEEESSSSHHHH-HHHHHHHHHHTHHHHHHHHH-SS??HHHHHHTGGG----------S????HHHHHHH---TT??S?EEEEEEEEEEEEE??------??SS????SGGGGG?EEEESB?TTS?BSS?B?SSSS?B??THHHHHHHHHHHHTS??--??EEEEE????EE??SSS???HHHHH??HHHHHHHHHHHHHHHHHH-HTT??EEEEEEE?SB????GGGT-TSEE??SEEEEG----GGTTEEEE?HHHHHHHHHHH???? 4IPL|A PF00233.14_PDEase_I_seed 8 258 !Q:19,19|25,25|27,27|45,46|49,49|57,58|60,60|70,70|91,91|97,97|116,116|134,135|137,137|139,145|148,148|150,152|171,171|176,176|203,207|211,211|215,217|244,244 Q:0,18|20,24|26,26|28,44|47,48|50,56|59,59|61,69|71,90|92,96|98,115|117,133|136,136|138,138|146,147|149,149|153,170|172,175|177,202|208,210|212,214|218,243|245,257 SSSHHHHHHHHHHHHHHTT?GGGTT?S?HHHHHHHHHHHHHTTTT??SS?HHHHHHT--T?HHHHHTTTS-SHHHHHHHHHHHHHTSSGGG?TTTTS?HHHHHHHHHHHHHHHHTT?GGGHHHHHHHHHHHHHT??B?T-------TS?B???SHHHHHHHHHHHHHHHHT?GGGS?HHHHHHHHHHHHHHHHHHHHHHHHTT??-??TTT?TTT?-?HHHHHHHHHHHTHHHHHHHHHHHSTT-TTHHHHHHHHHHH 1XM4|A PF00234.17_Tryp_alpha_amyl_seed 187 218 !Q:7,36|47,50|52,58|72,83|104,183|185,186|199,205|208,209|211,212|216,216 Q:0,6|37,46|51,51|59,71|84,103|184,184|187,198|206,207|210,210|213,215|217,217 HHHHHHH------------------------------HGGGHHHHHH---?S----???HHHHHHHHHHHHH??----------SHHHHHHHHHHHHHHHHHST--------------------------------------------------------------------------------T??HHHHHHHHHHTT?----??SS??S--TTS?G 1FK0|A PF00235.14_Profilin_seed 72 226 !Q:0,0|7,11|16,17|20,23|26,27|35,35|37,37|39,41|43,55|59,61|63,63|66,73|75,94|104,104|108,113|115,117|124,124|137,138|141,145|149,150|158,158|162,166|172,172|182,182|185,203|205,205|209,209|216,219 Q:1,6|12,15|18,19|24,25|28,34|36,36|38,38|42,42|56,58|62,62|64,65|74,74|95,103|105,107|114,114|118,123|125,136|139,140|146,148|151,157|159,161|167,171|173,181|183,184|204,204|206,208|210,215|220,225 ?HHHHHH-----HHHS??BT----TB??SEEEEEE-T-T---S-?-----------EEE---E?TT---?????H--------------------HHHHHHHHH-HHS------T---TSSTTT?EEETTEEEEEEE--EE-----TTT--EEEEEET-TEE-----EEEEE?SSEEEEEEE?TT-------------------S?HHH-HHHHHH----HHHHHH 2JKG|A PF00236.13_Hormone_6_seed 10 97 !Q:0,8|10,12|28,28|43,44|51,51|54,55|72,73|79,79|84,85|92,97 Q:9,9|13,27|29,42|45,50|52,53|56,71|74,78|80,83|86,91 ???----??B???SEEEEEEEEEETTEE-EEEEEEEEEEEEEE??HHHHTT?SS??SEEEEEEEEEESSEEE??BTTTB?BEEE??EEEEES?????- 1DZ7|A PF00237.14_Ribosomal_L22_seed 126 169 !Q:3,5|7,8|10,10|42,42|45,45|49,49|52,73|75,76|81,81|83,83|88,89|108,109|111,116|120,120|122,123|127,127|135,139|142,142|158,161|168,168 Q:0,2|6,6|9,9|11,41|43,44|46,48|50,51|74,74|77,80|82,82|84,87|90,107|110,110|117,119|121,121|124,126|128,134|140,141|143,157|162,167 EEE--?S??S?HHHHHHHHHHHTTSBHHHHHHHHHHHHHTSS?EE?SSS?TT?--------------------?B??STTS?S?SBEE??HHHHHHHHHHHHHHHHHH--H------HHT-S?-TTT?EEEEEEE?????EE-EEEEETTTEEEEEEE????EEEEEE? 2ZJQ|P PF00238.14_Ribosomal_L14_seed 103 203 !Q:0,0|2,2|5,5|10,10|16,23|31,31|33,36|38,38|43,45|47,48|50,57|59,59|62,62|69,69|73,80|82,89|94,94|96,99|101,101|110,110|113,114|117,118|122,122|129,129|134,137|140,140|142,150|154,154|156,159|161,163|167,167|169,178|181,181|183,191|198,198|200,202 Q:1,1|3,4|6,9|11,15|24,30|32,32|37,37|39,42|46,46|49,49|58,58|60,61|63,68|70,72|81,81|90,93|95,95|100,100|102,109|111,112|115,116|119,121|123,128|130,133|138,139|141,141|151,153|155,155|160,160|164,166|168,168|179,180|182,182|192,197|199,199 ?B?TT?EEEE?BSSSE--------EEEEEEE-E????B?SSSB???S?-S----????B?SS?EEEEEE-EEE-------?S--------SSSS?T----T?EEEEEEEE?SS?-EE-?TTS?EEEESS?EEEE??--TT-T-?------?SSS?B?---S???THH-H----------HT-T--------?HHHHTT?S??? 2ZJQ|H PF00239.16_Resolvase_seed 222 223 !Q:0,0|3,3|6,8|11,16|19,23|28,28|37,48|50,57|60,62|65,65|67,70|72,72|74,78|87,87|89,90|92,93|95,107|112,112|118,120|128,128|133,133|138,140|145,146|148,148|150,153|157,168|173,173|177,179|188,191|195,196|207,222 Q:1,2|4,5|9,10|17,18|24,27|29,36|49,49|58,59|63,64|66,66|71,71|73,73|79,86|88,88|91,91|94,94|108,111|113,117|121,127|129,132|134,137|141,144|147,147|149,149|154,156|169,172|174,176|180,187|192,194|197,206 ?EE?EE?--SS??----SS-----HHHH-HHHHHHTT-??---------B-?-----?EE?-?SS?S----S-S--?--STTHHHHH-T??T--T---?--?------EEES?STTTT??-HHHHHHH-HHHH-HTTT???EETT--T-T----EES------------SSHH-HHH---HHHHHHHH----HHH--HHHHHTTTTT??-??????---???? 1HX7|A PF00240.18_ubiquitin_seed 76 84 !Q:1,1|4,13|19,20|23,23|37,42|46,47|55,58|68,69|72,74|79,83 Q:0,0|2,3|14,18|21,22|24,36|43,45|48,54|59,67|70,71|75,78 E?TT??--------EEEEE??TT?BHHHHHHHHHHHH?---??GGG??EEETTEE?--?TTSBTGGGT??TT?--EEEE????? 2FCS|A PF00241.15_Cofilin_ADF_seed 16 179 !Q:12,12|15,16|18,19|26,26|29,32|34,34|40,41|45,52|55,57|59,59|62,62|87,87|98,103|107,110|120,122|125,126|128,128|138,138|148,148|151,151|155,155|161,162|169,169 Q:0,11|13,14|17,17|20,25|27,28|33,33|35,39|42,44|53,54|58,58|60,61|63,86|88,97|104,106|111,119|123,124|127,127|129,137|139,147|149,150|152,154|156,160|163,168|170,178 THHHHHHHHHHH?SS--S??EEEEEE?SS----S?EEEEE??GGG--------GT---S?SS?HHHHSSHHHHHHHHHTTHHHHSSS?EEEEEEEEEE?--???SSS????EEEEEEEEE?-?SS--S?HHHHHHHHH-HHHHHHHHH?SS-SSE-EEEES--SSGGGS-HHHHHHHHH 3Q2B|A PF00243.13_NGF_seed 7 126 !Q:0,8|12,12|19,24|32,32|37,37|39,51|58,61|65,65|73,74|78,78|82,83|98,104|120,125 Q:9,11|13,18|25,31|33,36|38,38|52,57|62,64|66,72|75,77|79,81|84,97|105,119 ?????????BSS?EEEEEE?--???EEEBTTS?EEEB?S?????????????EEEEEE????TTT?SSSSTTS??TTB?TTT??EEEEEEEEEEEEEE???????EEEEEEEEEEEEEEE?????? 4EAX|A PF00244.15_14-3-3_seed 85 329 !Q:5,6|15,15|18,19|21,24|38,49|53,55|74,74|82,83|91,92|96,119|121,122|159,182|186,186|206,208|210,217|222,222|241,243|246,247|249,249|252,252|271,272|294,295|297,304|308,308|322,328 Q:0,4|7,14|16,17|20,20|25,37|50,52|56,73|75,81|84,90|93,95|120,120|123,158|183,185|187,205|209,209|218,221|223,240|244,245|248,248|250,251|253,270|273,293|296,296|305,307|309,321 HHHHH--HHHHHHHH-HT?-H----HHHHHHHHHHHHT?-----------SSS???HHHHHHHHHHHHHHHHHH-HHHHHHH--HHHHHHH--HTT------------------------T?-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHH----------?---------?---SHH-HHHHHHHHHHHHHHHHHHH?-?S--------HHHH-HHHHHHHHHHHHHHHHHH---HH--S?TT?HHHHHHHHHHHHHHHHTS??HHHHHHHHHHHHHHHHHHHHH--T??-?????HHH-HHHHHHHHHHHHT??????? 3P1N|A PF00245.15_Alk_phosphatase_seed 10 539 !Q:0,0|11,12|30,30|35,36|41,41|49,51|54,54|56,61|63,64|77,79|82,82|86,86|90,90|92,93|95,95|99,99|102,102|104,108|118,118|138,139|142,142|145,146|152,157|165,172|182,186|193,194|202,204|207,207|210,210|215,216|220,222|229,232|235,235|242,242|246,248|256,256|259,260|266,266|271,273|276,296|298,299|303,305|319,319|321,321|323,328|330,330|348,348|371,373|385,385|389,394|398,398|400,402|405,406|411,411|414,416|420,422|430,432|436,438|441,465|468,472|474,474|482,485|489,490|493,494|497,497|499,499|511,517|519,520|538,538 Q:1,10|13,29|31,34|37,40|42,48|52,53|55,55|62,62|65,76|80,81|83,85|87,89|91,91|94,94|96,98|100,101|103,103|109,117|119,137|140,141|143,144|147,151|158,164|173,181|187,192|195,201|205,206|208,209|211,214|217,219|223,228|233,234|236,241|243,245|249,255|257,258|261,265|267,270|274,275|297,297|300,302|306,318|320,320|322,322|329,329|331,347|349,370|374,384|386,388|395,397|399,399|403,404|407,410|412,413|417,419|423,429|433,435|439,440|466,467|473,473|475,481|486,488|491,492|495,496|498,498|500,510|518,518|521,537 ?SEEEEEEETT??HHHHHHHHHHHHHHTTS?STTS??TGGG?SEEEEEE???SS?S------S??HHHHHHHHHHSS???TT?BSB?TTS?T--T?GGG?TT?B?--??HHHHHHHTT?EEEEEEEEETTSHHHHTTT??BS?TT??SGGGS-----?HHHHHTT-----???HHHHHHHTS---??SEEEEE??GGGSBTT???SS?TT?GGGS??BSS???HHHHHH----HT?TTEEEE?SHH---HHHHHHT?TT??EEEEE?SSSS???GG---------------------G??TTT???HHHHHHHHHHHHT-T?T------T?EEEEEEETTHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHS--?TTTEEEEEEES?EES------EEE?S???TT??TTSB?SS??-TTS???BSEEEEE---STT???BT-------------------------TB?????H-HHHTSTT????EEE??SS??EE?S?EEEEEESTTGG-------G??SEEETTHHHHHHHHHTT? 1KHL|A PF00246.19_Peptidase_M14_seed 114 612 !Q:9,10|18,19|25,25|28,29|32,33|41,41|44,77|81,83|90,90|95,97|109,113|121,132|145,145|152,152|154,154|163,164|166,204|206,206|209,210|212,222|224,224|228,252|254,254|256,258|262,276|278,285|289,289|291,294|296,296|298,299|301,302|305,305|312,313|318,332|341,341|344,344|346,348|351,360|362,363|375,375|379,387|390,390|392,420|422,422|424,452|458,465|480,480|483,503|507,507|512,519|521,523|525,529|531,531|535,539|543,543|547,547|549,554|563,563|568,587|591,592|594,598 Q:0,8|11,17|20,24|26,27|30,31|34,40|42,43|78,80|84,89|91,94|98,108|114,120|133,144|146,151|153,153|155,162|165,165|205,205|207,208|211,211|223,223|225,227|253,253|255,255|259,261|277,277|286,288|290,290|295,295|297,297|300,300|303,304|306,311|314,317|333,340|342,343|345,345|349,350|361,361|364,374|376,378|388,389|391,391|421,421|423,423|453,457|466,479|481,482|504,506|508,511|520,520|524,524|530,530|532,534|540,542|544,546|548,548|555,562|564,567|588,590|593,593|599,611 HHHHHHHHH--HHSTTTE--EEEEE-EE-?TT??EEEEEEE?SS----------------------------------TTS???EEEEEE?SSTT?--HHHHHHHHHHH-----HHHHHST------------TTSHHHHHHHHH?EEEEES?S?HHHHHHHH--H---------------------------------------T?TT??S?--------??B?TTS-------------------------S?B???GGG---------?-----S--------SSS-T----T?T--T-?BS?TTSTTB??SSTT?--------------SHHHHHHH-HH-H---HH----------H??EEEEEEEEESS?EEE---------ES?S-----------------------------S?S--------------------------???TTHHH--------HHHHHHHHHHHHHH-HH-------------???--?--EEE-EHHH--------H---S????-S?HHH-----HHH-HTT?S------EEEEEEES?SSSS--------------------TTS??G-----GGHHHHHHHHHHH 1PCA|A PF00248.16_Aldo_ket_red_seed 61 548 !Q:5,5|9,9|12,23|26,26|34,36|42,42|46,52|56,57|60,76|87,87|91,93|98,101|103,103|110,110|117,117|119,146|156,156|159,163|178,179|181,181|184,184|189,189|191,192|196,222|228,233|242,245|256,258|260,262|270,273|282,290|294,294|296,296|300,308|310,310|320,321|326,327|329,329|331,331|335,335|343,357|364,433|450,450|453,455|468,480|482,502|504,504|510,513|527,529|531,535 Q:0,4|6,8|10,11|24,25|27,33|37,41|43,45|53,55|58,59|77,86|88,90|94,97|102,102|104,109|111,116|118,118|147,155|157,158|164,177|180,180|182,183|185,188|190,190|193,195|223,227|234,241|246,255|259,259|263,269|274,281|291,293|295,295|297,299|309,309|311,319|322,325|328,328|330,330|332,334|336,342|358,363|434,449|451,452|456,467|481,481|503,503|505,509|514,526|530,530|536,547 SEEEE?SSS?ST------------TS?HHHHHHH---HHHHH-HTT??-----EEE??TT---------?-------TTTTTHHHHH-HHH---HHHH----H?TTTGGG?EEEEEE?S--------------------------??SSSTTSSSS?HH-----HHHHHHHHHHHHHT?-S?EE-EEEE?S??TTS?--------------------------HHHHH------HHHHHHHH----TTSEEEEEEE---S??-HHHHHHH----HHHHHTTT??-----??EEE?B?BTT---------B?HHHHTTHHH--HHHH--H-T?EEE-EBSTTGG---------------GGGGTS??????????????????---------------------------------------????-???---??HHHHHHHHHHHHHHHH-TT?-?HHHHHHHHHTSS-------------T---------------------T?SEEEE??--SSHHHHHHHHGGG---G?????HHHHHHHHHHHH 3DOP|A PF00249.26_Myb_DNA-binding_seed 194 75 !Q:0,1|3,4|19,19|22,41|51,59|61,62 Q:2,2|5,18|20,21|42,50|60,60|63,74 ??S??HHHHHHHHHHHHHH?TT-------------------?HHHHHTTST---------T??HHHHHHHHHHTT 2V1D|B PF00250.13_Fork_head_seed 21 140 !Q:0,1|3,23|25,25|37,37|42,42|44,44|56,56|62,62|77,77|84,92|94,94|97,97|100,100|105,105|109,109|113,113|115,130|132,132|136,136|139,139 Q:2,2|24,24|26,36|38,41|43,43|45,55|57,61|63,76|78,83|93,93|95,96|98,99|101,104|106,108|110,112|114,114|131,131|133,135|137,138 ??S---------------------S?HHHHHHHHHHT-STTS?B?HHHHHHHHHHH?GGGGS?HHHHHHHHHHHHHH?TTEEEE??------?S?SS?SS?EEEE?GGG?STT?S----------------S?SSS?SS? 2A07|F PF00251.15_Glyco_hydro_32N_seed 138 468 !Q:1,3|17,18|30,30|32,32|34,34|37,38|40,43|45,46|53,53|65,65|69,72|79,81|90,90|93,93|95,109|118,121|123,133|135,135|137,138|148,149|152,152|155,157|161,162|165,167|170,174|178,181|187,191|194,197|200,200|202,202|213,217|228,229|232,233|237,238|241,241|244,244|250,250|252,256|258,259|271,271|273,278|280,293|296,298|302,304|306,306|316,329|338,338|343,343|347,347|353,353|356,356|359,364|369,370|372,376|379,379|383,385|394,398|411,413|416,416|418,418|424,429|434,436|439,441|447,457 Q:0,0|4,16|19,29|31,31|33,33|35,36|39,39|44,44|47,52|54,64|66,68|73,78|82,89|91,92|94,94|110,117|122,122|134,134|136,136|139,147|150,151|153,154|158,160|163,164|168,169|175,177|182,186|192,193|198,199|201,201|203,212|218,227|230,231|234,236|239,240|242,243|245,249|251,251|257,257|260,270|272,272|279,279|294,295|299,301|305,305|307,315|330,337|339,342|344,346|348,352|354,355|357,358|365,368|371,371|377,378|380,382|386,393|399,410|414,415|417,417|419,423|430,433|437,438|442,446|458,467 S???SSEEEEEEEEEEE--ETTEEEEEEEE?T-T?SS--S--?-S-?EEEEEE-ESSSSSBEEEE-EEE???-SGGGTT?--EEEEEEEE?TT-S?--------------EEEEEEEE---?T-----------T-S-?EEEEEEEES-?TT?TT???EEE-?TT-??SB??--?TTT?-??TTSEE?????EE?---TT-S?EEEEEEEEET-----TEEEEEEEEE--SS--SSS?-EE?SS?SEEEE-T-----S??EEEEEEEEEES-S-----?S??----------??TT???BTT---B?EEEEEEEEE--------------TTTTEEEE-EEEE-EET-TTTEE-EE?TT----??SSTT--S?----BS?SSS--?EEEEEEEE-----TTTTEEEEEEEE?-?SS?H-HHHHH------HTEE?--EE???EEEEE---------?-TTSSSEEEEE 3PIJ|A PF00252.13_Ribosomal_L16_seed 141 252 !Q:0,18|21,45|47,47|50,60|63,64|68,82|87,87|89,89|91,93|103,110|117,133|136,154|157,163|166,168|172,175|179,189|196,197|199,199|201,201|207,213|215,215|217,219|221,227|244,244|246,247|251,251 Q:19,20|46,46|48,49|61,62|65,67|83,86|88,88|90,90|94,102|111,116|134,135|155,156|164,165|169,171|176,178|190,195|198,198|200,200|202,206|214,214|216,216|220,220|228,243|245,245|248,250 ????---------------SS??------???--??------?-??S?SS---------??SS?-SSS--------------?EEEE?S?B-??BTHHHHHHH--------HHHHHH?----------------SS---???----------???TT---????EE???SSS??-?SSS?---------?TTSEEB??B?T-TEEEE??---?-S-S--?S-------TTTTTHHHHHHTTSSS?E--EEE? 2ZJQ|J PF00253.16_Ribosomal_S14_seed 178 62 !Q:2,3|8,8|11,12|16,20|24,26|28,29|32,32|36,40|53,53|57,57|60,61 Q:0,1|4,7|9,10|13,15|21,23|27,27|30,31|33,35|41,52|54,56|58,59 HH--HTTS?SS??TTS?????SSS???T--TB?TTT-??--BTHHHHHHHHTT?SSS?EE?? 3KIX|n PF00254.23_FKBP_C_seed 174 247 !Q:1,1|3,5|8,9|12,17|26,32|34,34|36,38|40,40|42,51|56,65|68,74|77,78|86,88|91,93|95,95|97,118|127,138|142,142|149,149|151,151|158,195|197,197|199,199|203,207|209,209|212,238|247,247 Q:0,0|2,2|6,7|10,11|18,25|33,33|35,35|39,39|41,41|52,55|66,67|75,76|79,85|89,90|94,94|96,96|119,126|139,141|143,148|150,150|152,157|196,196|198,198|200,202|208,208|210,211|239,246 S?B-??TT?-EE------EEEEEEEE-------T-T---S?E----------EEEG----------GG-------GT??EEEETTS---SS---S?H----------------------HHHHHHTT-----------?BTT?EEEEEE?G-GGTTTT--------------------------------------T?B-TTT-----B?TT-------------------------??EEEEEEEE- 3PRD|A PF00255.14_GSHPx_seed 12 117 !Q:3,3|6,6|11,11|13,13|30,30|62,63|68,70|72,72|86,86|88,89|91,93|99,101|109,109 Q:0,2|4,5|7,10|12,12|14,29|31,61|64,67|71,71|73,85|87,87|90,90|94,98|102,108|110,116 GGG?EE?BTTS?S?EEGGGGTTSEEEEEEE?SSSTTHHHHHHHHHHHHHHHGGGTEEEEEEE??TTTT???S?HHHHHHHHHHTSS?T--T???SSEEB???BSSSTTB?HHHHHHH 2RM6|A PF00258.20_Flavodoxin_1_seed 92 241 !Q:4,4|22,23|37,37|40,47|52,52|60,61|67,68|73,75|86,96|103,149|154,154|163,163|169,175|190,190|193,193|198,221|229,231 Q:0,3|5,21|24,36|38,39|48,51|53,59|62,66|69,72|76,85|97,102|150,153|155,162|164,168|176,189|191,192|194,197|222,228|232,240 EEEE?SSSHHHHHHHHHHHHHT--TTSEEEEEETTTS?TT--------SGGG?SEEEEEE??BTTTB??GGGH---HHHHHHHHHT???????????HHHHTS????---------------------??????????????????????TTTT?EEEEEEEE?TTSSS-------TTHHHHHHHHHHHH-TT?EESS----------------------??EEEETTT---THHHHHHHH 2BMV|A PF00261.15_Tropomyosin_seed 43 238 !Q:76,76|237,237 Q:0,75|77,236 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH? 1MV4|A PF00262.13_Calreticulin_seed 68 459 !Q:0,0|5,7|10,16|18,19|21,44|48,49|51,53|56,56|61,61|63,64|68,68|71,73|79,80|86,86|89,89|91,124|126,126|134,135|137,137|139,140|145,146|152,153|156,157|159,161|164,171|174,177|190,191|193,193|200,200|203,203|206,206|208,209|214,218|221,222|229,230|232,233|245,245|260,275|278,281|283,283|286,289|292,295|300,300|302,302|304,307|310,311|314,315|317,317|321,321|324,328|331,331|336,336|338,339|341,341|344,347|350,355|360,365|367,369|376,377|379,379|383,386|390,390|393,395|397,400|404,404|407,409|411,414|416,418|421,427|430,436|443,446|450,451|453,453 Q:1,4|8,9|17,17|20,20|45,47|50,50|54,55|57,60|62,62|65,67|69,70|74,78|81,85|87,88|90,90|125,125|127,133|136,136|138,138|141,144|147,151|154,155|158,158|162,163|172,173|178,189|192,192|194,199|201,202|204,205|207,207|210,213|219,220|223,228|231,231|234,244|246,259|276,277|282,282|284,285|290,291|296,299|301,301|303,303|308,309|312,313|316,316|318,320|322,323|329,330|332,335|337,337|340,340|342,343|348,349|356,359|366,366|370,375|378,378|380,382|387,389|391,392|396,396|401,403|405,406|410,410|415,415|419,420|428,429|437,442|447,449|452,452|454,458 ?SSEE???SS-------S??S???????????----?????????EEE??B?--TT?SSTT?B??EEE?SS???EEEEE--EEEEE?SS-S----------------------------------S?EEEEEEE??T-T??SEEE??EEEEB??SS??G---GG--??----SS?--?EEEEEEEEEESS??E-EEEEEE-EE?TT-T??EEEE?????SS??THHHHS-?S-?EEEEEEEETTT-EEEEEETTEEEEEE-?????-----?????SS????B?TT????TT????SEEE?S-S????TT??SS??S-EEE?TT?-???SS?BSSS?S??B?TT????TT??----TTTS??????B???GGGTTS--S?BSS????EEE?TT???S????EEE?TT???S????B???TT?????-?TT-??--??EEEEEE????SSS??B?EEEEE 3POW|A PF00264.15_Tyrosinase_seed 127 578 !Q:8,24|31,33|36,46|49,79|81,84|86,87|90,93|108,112|123,128|134,134|139,149|159,162|164,165|169,187|189,192|197,199|201,201|207,211|216,216|218,256|262,262|266,267|269,269|272,272|280,308|312,312|315,316|319,319|321,321|325,325|332,333|335,335|345,347|355,359|364,387|395,430|436,436|440,468|472,474|485,485|489,489|493,501|504,506|509,524|527,527|529,543|545,548|550,550 Q:0,7|25,30|34,35|47,48|80,80|85,85|88,89|94,107|113,122|129,133|135,138|150,158|163,163|166,168|188,188|193,196|200,200|202,206|212,215|217,217|257,261|263,265|268,268|270,271|273,279|309,311|313,314|317,318|320,320|322,324|326,331|334,334|336,344|348,354|360,363|388,394|431,435|437,439|469,471|475,484|486,488|490,492|502,503|507,508|525,526|528,528|544,544|549,549|551,577 TTSHHHHH-----------------HTTSTT???BT-----------TB??------------------???????????S?-??S--ST----THHHHHHHHHHHHH-----HHHHHHHHHH------HHHHS?HHHH-----------HHHHHHHHH????B??TTS??-??????-?-----???S????TGGG--?S-EEEEE?----TTST-T?--------------------------------------EEEEE?TTT??B?SS?GGGSSTT?????------???-????----??????GGG?SB??BS?B?SSS?GGGGGG??B?HHHHHHHHT???GGGGSTT?????HHHH------------------------HHHHHHH??-------------------------------???HHHHH?SEE??????------????-???-------??GGG???HHHHHHHHHH-HHH?EES-------??SS-??SS-------------???EE?G---------------G----G?TTTGGGSTHHHHHHHHHHHHHHHHHHH 1HC1|A PF00265.13_TK_seed 13 191 !Q:0,0|7,7|29,30|37,37|39,67|70,70|81,83|94,94|96,97|111,111|117,118|121,121|125,125|127,127|137,137|143,144|147,147|151,151|154,154|156,156|163,168|170,172|174,178|186,186 Q:1,6|8,28|31,36|38,38|68,69|71,80|84,93|95,95|98,110|112,116|119,120|122,124|126,126|128,136|138,142|145,146|148,150|152,153|155,155|157,162|169,169|173,173|179,185|187,190 ?EEEEEE?STTSSHHHHHHHHHHHHHTTT??EEEEEB?S???????-----????????????----?BS?HHHHTTTGGG--?SEEEEETGGG?T--THHHHHHHHHHTT?EEEEE??SB?TTS?B?TTTGGGGGS?SEEEE??EE?TTT?SE-E?EEEESS------S???S?????TTTEEEE?HHHH 2QQ0|A PF00266.14_Aminotran_5_seed 45 426 !Q:2,3|7,11|26,29|32,34|59,59|61,61|74,74|88,93|96,96|104,105|121,121|125,126|129,130|132,132|136,136|138,140|145,145|149,154|166,166|170,172|174,175|186,186|188,188|190,190|196,196|204,206|212,212|222,222|226,226|229,229|235,235|242,246|249,249|257,258|262,263|265,268|270,271|277,279|282,283|298,298|302,302|324,324|331,332|335,339|342,343|351,351|354,355|357,360|371,371|375,375|378,379|381,381|384,388|397,397|399,406|412,414|417,418 Q:0,1|4,6|12,25|30,31|35,58|60,60|62,73|75,87|94,95|97,103|106,120|122,124|127,128|131,131|133,135|137,137|141,144|146,148|155,165|167,169|173,173|176,185|187,187|189,189|191,195|197,203|207,211|213,221|223,225|227,228|230,234|236,241|247,248|250,256|259,261|264,264|269,269|272,276|280,281|284,297|299,301|303,323|325,330|333,334|340,341|344,350|352,353|356,356|361,370|372,374|376,377|380,380|382,383|389,396|398,398|407,411|415,416|419,425 EE??TTT?????HHHHHHHHHHHHHT????SS--?SSHHHHHHHHHHHHHHHHHHHHTT?S?GGGEEEESSHHH-HHHHHHHHHHHHH----??TT?EEEEETT??GGGTHHHHHHHHHHT?EEE--EE-?B?TTS?B?--GGGH-HHH?---?-TTEEEEEEESB?TTT??-B??HHHHHHHHHH-T-T?EEEEE?TTTTTTS???HHHHT?SEEEEEGGG-TTS?SS?EEEEE?HHHHTT?--??SS?SSSSEEE??TTT??E----E??TTGGG?-?SS??HHHHHHHHHHHHHH-HHH?HHHHHHHHHHHHHHHHHHHTT-STTEEE--ES-?---TT??SEEEEEE-TT??H----HHHHHHHHHT-TEE?EE--E?TT?----HHHHHHTT?S-------?EEEEE-??TT??HHHHHHH 2YRI|A PF00267.16_Porin_1_seed 18 423 !Q:5,15|29,29|31,32|37,41|44,45|54,57|61,64|76,76|79,85|110,110|120,121|126,126|128,128|131,135|150,150|170,214|224,224|226,226|229,229|239,269|272,273|293,320|330,330|332,332|336,336|348,351|356,362|364,365|367,367|369,371|395,398|401,401|407,410|412,412|422,422 Q:0,4|16,28|30,30|33,36|42,43|46,53|58,60|65,75|77,78|86,109|111,119|122,125|127,127|129,130|136,149|151,169|215,223|225,225|227,228|230,238|270,271|274,292|321,329|331,331|333,335|337,347|352,355|363,363|366,366|368,368|372,394|399,400|402,406|411,411|413,421 ETTEE-----------EEEEEEEEEEEEE?S-?TTTS-----EE??EEEEEEEE????SSS????EEEEEEEESSS?TT?--??--EEEEEEEEEEEETTTEEEEEEEEE?TTHHHHGGG??SSSS?S?SS----?TTSTTSSEEEEEEE-EEEESHHHHSTTEEEEEEE??????????--------????????------?????--------EEEEEEEEE?S-TT?EEEEEEEEE???????----------??????????????EE??EEEEEEETTEEEEEEEEEB???????????----?????????????EEEEEEEEE?B-TTT-EEEEEEEEEEE????BSSS-----??B??S?B???EEEEEEEEEEETTEEEEEEEEEE????SS-HHHHT????S?EEEEEEEEE? 3A2S|X PF00268.16_Ribonuc_red_sm_seed 13 299 !Q:0,0|6,7|9,11|15,17|31,33|38,39|49,49|51,51|84,86|115,117|132,132|148,148|152,152|183,184|212,212|214,216|218,220|225,228|245,247|251,251|257,261|282,284|287,294|298,298 Q:1,5|8,8|12,14|18,30|34,37|40,48|50,50|52,83|87,114|118,131|133,147|149,151|153,182|185,211|213,213|217,217|221,224|229,244|248,250|252,256|262,281|285,286|295,297 ?TTTSS??S???SSS???HHHHHHHHHHHHT???GGGS??TTHHHHHHH-S?HHHHHHHHHHHHHHTTHHHHHHHHHHTTHHHH???HHHHHHHHHHHHHHHHHHHHHHHHHHHH?-?SHHHHHHHHTTTTT?HHHHHHHHHHHHHHH?SSS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHHHHHHHHHHTT?S---S???HHHH----HHHHHHHHHHHHHHHH---TTS?GGGGT??---HHHHHHHHHHHHHHHHHHTT???SS????--??TTT? 1H0N|A PF00269.15_SASP_seed 66 91 !Q:0,2|7,8|17,32|42,49|52,58|67,67|69,72|90,90 Q:3,6|9,16|33,41|50,51|59,66|68,68|73,89 ???SSGG--GHHHHHHH----------------HHHHHHHHT----?-??ST-------TSBHHHHH-H----HHHHHHHHHHHHHHHTT? 2Z3X|A PF00270.24_DEAD_seed 182 548 !Q:0,0|3,3|5,7|13,15|19,20|22,22|24,38|41,48|51,52|64,66|70,72|78,79|81,184|187,298|304,304|318,320|327,340|343,357|360,363|365,372|375,377|380,380|387,394|397,399|405,405|409,413|421,424|427,437|440,442|444,445|457,462|464,465|470,473|478,483|487,489|493,493|495,510|512,529|531,531|538,541 Q:1,2|4,4|8,12|16,18|21,21|23,23|39,40|49,50|53,63|67,69|73,77|80,80|185,186|299,303|305,317|321,326|341,342|358,359|364,364|373,374|378,379|381,386|395,396|400,404|406,408|414,420|425,426|438,439|443,443|446,456|463,463|466,469|474,477|484,486|490,492|494,494|511,511|530,530|532,537|542,547 ?HH-H---HHHHH---HHH--T-T------------??-EE--------EE??TTSSHHHHHHH---HHH---HHHHH--S?????---------------------------------------------------------------------------------------------------TT?--------------------------------------------------------------------------------------------------------------?SEEEE?SSHHHHHHHHHHH---HHHTTT--------------SS?-----------???EE---?T--------TS?--HH-HHHHHH--------TT?-?SEEEE?HHH-----HHHHHHT----TS???--------TT-??E--EEEETHHHHTS------T--TTHH----HHHH------HHH?--TTS?S----------------S-----------------?E-EEEEES???-HHHHHH 2YKG|A PF00271.26_Helicase_C_seed 480 163 !Q:7,8|13,13|15,33|36,36|53,87|93,93|100,102|104,105|113,134|136,136|140,150|159,160 Q:0,6|9,12|14,14|34,35|37,52|88,92|94,99|103,103|106,112|135,135|137,139|151,158|161,162 HHHHHTT??EEEE?S-------------------SS?HHHHHHHHHHHHTTSS-----------------------------------SEEEE?TTHHHH???S??SEEEESS?--------------------?S?HHH-----------HHHHSTTT??SS 2YKG|A PF00272.14_Cecropin_seed 28 34 !Q:19,22|24,25 Q:0,18|23,23|26,33 HHHHHHHHHHHHHHHHHHH----T??SHHHHHHH 2LA2|A PF00273.15_Serum_albumin_seed 42 186 !Q:11,11|27,27|31,31|52,52|56,57|63,63|75,75|80,80|83,85|92,92|96,96|105,106|109,109|111,124|135,135|154,155|176,177|180,180 Q:0,10|12,26|28,30|32,51|53,55|58,62|64,74|76,79|81,82|86,91|93,95|97,104|107,108|110,110|125,134|136,153|156,175|178,179|181,185 SSHHHHHHHHH?HHHHHHHHHHHHHHH?TTS?HHHHHHHHHHHHHHHHHHHH?TTS--TTTTS?HHHHHHHHHHT?TTTT?SS???TTGGGS?TTH-HHHHHHHT??SS?S-??????-----??HHHHHHHHHH?HHHHHHHHHHHHHHHSTT??HHHHHHHHHHHHHHHHHHHT--TS?HHHHH 1LOT|A PF00274.14_Glycolytic_seed 58 424 !Q:10,10|13,13|19,24|37,40|45,52|62,63|76,76|82,82|84,84|87,87|89,89|96,96|101,101|107,110|114,114|120,121|125,151|166,167|176,185|188,188|190,190|213,213|222,224|227,228|252,253|257,257|259,259|261,268|271,273|275,280|297,297|301,301|307,307|310,311|326,338|341,345|367,367|371,373|395,420|423,423 Q:0,9|11,12|14,18|25,36|41,44|53,61|64,75|77,81|83,83|85,86|88,88|90,95|97,100|102,106|111,113|115,119|122,124|152,165|168,175|186,187|189,189|191,212|214,221|225,226|229,251|254,256|258,258|260,260|269,270|274,274|281,296|298,300|302,306|308,309|312,325|339,340|346,366|368,370|374,394|421,422 HHHHHHHHHT?TT?EEEEE-?--??HHHHHHHHHTTT????HHHH--------HHHHHHHHT??GGGTTTEEEEEE?HHHHT?B?TT-S?BHHHHH-HHTT?EEEEE????EEE?TTSSS-?EEE?------------------------??TTHHHHHHHHHHTT??EEEEEEEE??-----?--SS?S?HHHHHHHHHHHHHHHHHHHHTT?EEEEEEEE???SS??HHHHHHHHHHHHHHHHHHHHHTT??GGG?E-E????????TT??-S--?-??HHHHHHHHHHHHHTTS?TTS?EEEEE?TT??HHHHHHHHHHHHHS-------------SS--???SEEEEEESHHHHHHHHHHHTT?GGG---HHHHHHHHHHHHHHHHHHTTT???????------?????????????TT? 2QUV|A PF00275.15_EPSP_synthase_seed 23 503 !Q:1,4|11,11|13,14|16,16|34,37|43,45|61,62|67,67|71,72|77,78|81,89|96,96|99,99|113,113|116,121|128,129|136,137|149,150|161,161|167,172|182,182|195,195|200,200|208,208|211,211|228,230|233,233|238,239|244,244|247,250|252,253|255,255|259,260|262,262|279,279|286,287|290,293|301,301|308,312|316,322|324,324|332,343|345,346|349,350|352,352|371,377|379,379|385,385|394,394|408,408|413,413|415,425|430,434|437,438|441,449|452,453|456,456|468,469|474,482|495,495 Q:0,0|5,10|12,12|15,15|17,33|38,42|46,60|63,66|68,70|73,76|79,80|90,95|97,98|100,112|114,115|122,127|130,135|138,148|151,160|162,166|173,181|183,194|196,199|201,207|209,210|212,227|231,232|234,237|240,243|245,246|251,251|254,254|256,258|261,261|263,278|280,285|288,289|294,300|302,307|313,315|323,323|325,331|344,344|347,348|351,351|353,370|378,378|380,384|386,393|395,407|409,412|414,414|426,429|435,436|439,440|450,451|454,455|457,467|470,473|483,494|496,502 E????EEEEEE-E??B?HHHHHHHHHHHHHSBSE----EEEES???SHHHHHHHHHHHHTT-?EEEE?TTS??EEEE??SS?????----TTEEEE?TT?HHHHHHHHHHTTS-SE------EEEEEE??GGGGGS??HHHHHHHHHTT??EEESSSTTSS?EEEEE--????EEEEEEESS?THHHHHHHHHGG-GSSS?EEEEEEE-EE?STHHHHHHHHHHHHTT???EE-ETTT--EEEE?SS???-B??S-EEE??B?HHHHHHHHHHHHHHEE-EEEEES??TT???-GGGGHHH-HHHHHT----?EEE-------E?SSEEEEE???--------?B??EE--E?TTSTTTHHHHHHHGGGSB-------S?EEEES?GGGGGSSS?HHHHHHHHHHHTT?EEEE?S-----------SEEE-----EE??SS-----????EE??TT?HHHHHHHHGGG--SSSS--------?EEEESGGGGGGT?TTHHHHH 1G6S|A PF00276.15_Ribosomal_L23_seed 12 98 !Q:2,4|6,9|12,12|22,25|27,28|31,32|46,55|57,59|61,64|68,71|73,75|77,83|85,85|87,88|91,97 Q:0,1|5,5|10,11|13,21|26,26|29,30|33,45|56,56|60,60|65,67|72,72|76,76|84,84|86,86|89,90 TT???B????HH-HHTHHHHSS????B??SS??SHHHHHHHHHSTT??????????B???B??--STT??-?B???B???????S-S?-TT??????? 2ZJQ|Q PF00278.17_Orn_DAP_Arg_deC_seed 105 288 !Q:10,20|23,24|37,37|42,42|57,59|73,73|96,96|110,113|118,118|126,126|131,131|138,146|152,198|215,215|218,219|221,226|230,231|242,250|254,255|262,263|270,273|277,282 Q:0,9|21,22|25,36|38,41|43,56|60,72|74,95|97,109|114,117|119,125|127,130|132,137|147,151|199,214|216,217|220,220|227,229|232,241|251,253|256,261|264,269|274,276|283,287 EEEEEEEEEE???????????TT??HHHHHHHHHHHT?STTS?HHHHHHHHHHHHHH---HHHHHHHHHTTSS?HHHHHHHHHHHHHHHHHHHHHS?TTSTTHHHHHHHH----HHHT?EEEEESS?HHHH?HHHHHH??----???EEESS?----------------------------------------------GGGTTSEEEEEEESSS?TT?-B?---??EEE--TTEEESSEEE?-----???TTS??EEEEES??SSHHHH??-?GGG??--??EEEEE 1SZR|A PF00280.13_potato_inhibit_seed 60 75 !Q:0,0|2,6|22,22|29,29|32,33|37,41|44,47|56,58|61,62|66,66|69,70|73,74 Q:1,1|7,21|23,28|30,31|34,36|42,43|48,55|59,60|63,65|67,68|71,72 ?S?????TTSHHHHHHHHHHHH?TTSEEE-EE--ETT??-??SS?--?TTEEEEEE---ET--TTE-EE??SS?? 4B1T|B PF00281.14_Ribosomal_L5_seed 17 61 !Q:2,3|7,10|18,24|28,30|44,45|48,51|53,54|59,60 Q:0,1|4,6|11,17|25,27|31,43|46,47|52,52|55,58 ST--TTS??--EEEEEEE???????TTT???SSSSTTTTTTTSS??EE????S??STTS?? 2ZJQ|D PF00282.14_Pyridoxal_deC_seed 11 406 !Q:6,8|11,11|14,15|18,20|36,38|45,45|49,53|67,70|76,76|96,97|101,101|104,104|107,107|109,109|116,116|140,140|144,144|161,161|165,166|175,175|177,179|184,186|188,189|192,194|210,210|221,221|225,226|228,229|240,245|248,248|254,254|269,271|279,279|285,285|292,293|296,296|312,315|319,320|323,324|329,330|339,344|382,382|385,385|388,389|391,396 Q:0,5|9,10|12,13|16,17|21,35|39,44|46,48|54,66|71,75|77,95|98,100|102,103|105,106|108,108|110,115|117,139|141,143|145,160|162,164|167,174|176,176|180,183|187,187|190,191|195,209|211,220|222,224|227,227|230,239|246,247|249,253|255,268|272,278|280,284|286,291|294,295|297,311|316,318|321,322|325,328|331,338|345,381|383,384|386,387|390,390|397,405 TTTTGG---GS?SS??SS???HHHHHHHHHHHTGGG???TTSTTB?SSS?????HHHHHHHHHHHHH????SSTTT?HHHHHHHHHHHHHHHHHHT??GGG?TT?TT?B?EEEEES?HHHHHHHHHHHHHHHHHHHHHHH?TTS?HHHHHTTEEEEEETTS?HHH--HHHHHHHT?E---EEEE???T--TS???HHHHHHHHHHHHHTT?EEEEEEEEBS?TTT??B??HHHHHHHHHH------HT?EEEEE?TTGGGGGGSGGGGG---GGTTGGG?SEEEE?HHHHSS??SS?EEEEESBHHHHHTTT????GGG??TT--TTTS??GGGGSSSS??--??THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?TT-EE??S---???SSEEEEEES 3HBX|A PF00283.14_Cytochrom_B559_seed 8 29 !Q:0,7|10,10 Q:8,9|11,28 ????????SS?HHHHHHHHHHHHHHHHHH 3PRR|E PF00284.15_Cytochrom_B559a_seed 25 40 !Q:7,9|12,12|15,15|18,19|21,26 Q:0,6|10,11|13,14|16,17|20,20|27,39 HHHHHTT???TT?SS?SS??S??????STTHHHHHHHHHH 3PRR|E PF00285.16_Citrate_synt_seed 121 511 !Q:2,6|9,14|22,32|37,38|51,51|53,53|55,69|75,75|83,88|101,101|104,104|106,117|119,121|125,127|133,133|135,135|137,137|140,140|155,155|160,167|169,170|173,173|175,177|188,188|200,201|206,211|214,220|223,224|226,226|228,230|240,241|245,264|280,282|285,285|299,300|319,319|332,336|338,348|361,361|363,363|367,372|377,377|382,382|384,385|403,410|412,418|434,434|441,441|443,447|449,449|462,462|464,465|467,468|491,494|496,496|498,501|504,510 Q:0,1|7,8|15,21|33,36|39,50|52,52|54,54|70,74|76,82|89,100|102,103|105,105|118,118|122,124|128,132|134,134|136,136|138,139|141,154|156,159|168,168|171,172|174,174|178,187|189,199|202,205|212,213|221,222|225,225|227,227|231,239|242,244|265,279|283,284|286,298|301,318|320,331|337,337|349,360|362,362|364,366|373,376|378,381|383,383|386,402|411,411|419,433|435,440|442,442|448,448|450,461|463,463|466,466|469,490|495,495|497,497|502,503 GG-----TT??????SSEEEET-----------TTTE--EEETTEEHHHHH-H-H??-------------HHHHH-HHHHHSS--?-??HHHHHHHHHHHH-HT?S----------??H---HHH---HGGGG-S?T-TS?HHHHHHHHHHHHHH-HHGG--------G??TT?H---HHHHHHHHHH-HHHHHHHHHHH--HHHH------HT???????TT--S?H---HHHHHHHHH??TTS?---------???-?-----HHHHHHHHHHHHHTS??-SS?HHHHHHHHHHTTT??HHHHHHHHHHHHHSHHHH?HHHHHHHHHHHH----?S-----------GGGHHHHHHHHH?T-TSS??---?TTBS?SSSS-S??HHHHHHHHHHHHHHHHH--------T??----?HHHHHHHHHHHHHTS?HHHHHT-T---??B?HHHHHHHHHHHT-T??G--GGHHHHHHHHHHHHHHHHHHHH----H-H?---TT???-??? 1K3P|A PF00286.15_Flexi_CP_seed 17 143 !Q:0,0|4,5|19,19|22,23|42,44|47,50|53,54|58,58|60,60|67,67|75,76|97,99|107,108|115,115|124,124|128,130|133,134|137,139 Q:1,3|6,18|20,21|24,41|45,46|51,52|55,57|59,59|61,66|68,74|77,96|100,106|109,114|116,123|125,127|131,132|135,136|140,142 ?SSS??HHHHHHHHHHHHH-TT??GGGHHHHHHHHHHHHHHH???TT????SB?-SST-T?BHHHHH-HHHHHTT??HHHHHHTTHHHHHHHHTTTS?-?TTTTTTT??GGGGGG?STTGGGTT?TTS???TT??SS???HHH 4DOX|A PF00287.13_Na_K-ATPase_seed 11 344 !Q:0,28|38,39|72,72|76,76|78,79|82,85|87,87|89,89|96,99|102,104|110,110|113,114|133,133|138,139|143,143|146,148|151,157|159,159|162,162|166,166|168,169|172,174|180,180|184,184|188,188|190,191|198,198|205,213|216,222|225,225|227,228|231,233|235,236|238,243|257,264|269,269|273,276|284,284|287,287|292,292|295,298|305,305|307,310|314,314|322,324|327,330|332,332|334,334|339,340 Q:29,37|40,71|73,75|77,77|80,81|86,86|88,88|90,95|100,101|105,109|111,112|115,132|134,137|140,142|144,145|149,150|158,158|160,161|163,165|167,167|170,171|175,179|181,183|185,187|189,189|192,197|199,204|214,215|223,224|226,226|229,230|234,234|237,237|244,256|265,268|270,272|277,283|285,286|288,291|293,294|299,304|306,306|311,313|315,321|325,326|331,331|333,333|335,338|341,343 ????????-----------??????????SEETTEESS??SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS?SSS?S??TT----S?S?BEEESS??--TT---SEEEE?SS-?TTTSHHHHHHHHHHGGGS?TTTS??TTT-EE???SS???????S?SS-SSS?S??EE???GGGSS-SSS?TTS-S??SSSSSS?EEEEEE?------??BT???????SS?S??SS-??S??T------TEEEEEEESSSSS?-??????EEEE?GGG---?SEEEGGG?SB?HHHH?TT????EEEEEE?S??--TTS?EEEEEEE?-?SS????S-S?TTBS??EEE 2YN9|B PF00288.21_GHMP_kinases_N_seed 455 130 !Q:4,4|9,13|16,16|20,20|33,36|42,46|48,51|53,54|56,57|63,63|67,77|79,89|104,105|112,114|119,122|128,128 Q:0,3|5,8|14,15|17,19|21,32|37,41|47,47|52,52|55,55|58,62|64,66|78,78|90,103|106,111|115,118|123,127|129,129 EEEE-EESS----?TT-SSS?HHHHHHHHHHHH----HHHHT-----T----S--S??TTTTT?SEE??--------?H-----------HHHHHHHHHHHHHH--HHHSSS?-?SHHH----HHHHH?S 2DEJ|A PF00289.17_CPSase_L_chain_seed 157 172 !Q:0,3|5,5|8,9|13,23|35,47|49,51|53,54|57,57|60,61|65,65|67,69|76,77|80,80|82,82|86,87|90,97|102,102|111,112|116,130|132,134|136,137|144,144|153,154|156,156|159,163|167,167 Q:4,4|6,7|10,12|24,34|48,48|52,52|55,56|58,59|62,64|66,66|70,75|78,79|81,81|83,85|88,89|98,101|103,110|113,115|131,131|135,135|138,143|145,152|155,155|157,158|164,166|168,171 ????B?BS??HHH-----------HHHHHHHHGGG-------------S?-?B??EE?ST--TSS?H---HHHHSS??EE?S-SSS--GG--------GTTS?HHHHHHHH--HHT--------?-----?S?-?B??SSSSTT?HHHHHHHH--T-TT?--??SSS?HHHH 3HO8|A PF00290.15_Trp_syntA_seed 18 279 !Q:8,10|22,24|40,40|47,64|69,69|71,72|87,87|91,91|97,97|105,105|109,112|122,123|130,131|135,135|147,147|151,151|154,154|157,158|169,170|172,172|176,177|180,192|205,208|212,212|215,216|229,229|235,235|245,250|254,254|266,268|271,271|278,278 Q:0,7|11,21|25,39|41,46|65,68|70,70|73,86|88,90|92,96|98,104|106,108|113,121|124,129|132,134|136,146|148,150|152,153|155,156|159,168|171,171|173,175|178,179|193,204|209,211|213,214|217,228|230,234|236,244|251,253|255,265|269,270|272,277 HHHHHHTT?-?EEEEEEETTSS?--HHHHHHHHHHHHHHT?SSEEEE??????????????????TTTS?S??HHHHHHHHHHHHHH?SSS?EEEEE?HHHHHHT?HHH----HHHHHHHHT??EEEETT??GGG?HHHHHHHHHTT?EEE?EE?TT??HHHHHHHHHH??S?EEE??TT????????????-HHHHHHHHHHTT-???EEE?SS??SHHHHHHHHHTT?SEEEE?HHHHHHHHT------TTT?HHHHHHHHHHH---HH-HHHHTT? 1KFK|A PF00291.20_PALP_seed 148 653 !Q:6,8|12,13|15,15|18,18|20,26|29,31|35,35|43,44|46,46|49,50|58,60|67,76|82,102|105,107|109,109|111,113|117,118|121,158|169,170|173,173|175,177|179,179|181,184|189,193|196,197|199,199|201,214|225,228|234,234|237,241|246,249|254,256|259,263|265,265|268,268|273,290|292,315|319,320|323,337|339,342|346,349|351,367|369,372|374,385|391,391|395,395|408,414|416,416|419,420|422,423|425,425|431,539|541,545|549,563|565,569|572,572|579,579|589,604|606,608|619,619|627,637|640,640|642,643|646,646|649,649|651,651 Q:0,5|9,11|14,14|16,17|19,19|27,28|32,34|36,42|45,45|47,48|51,57|61,66|77,81|103,104|108,108|110,110|114,116|119,120|159,168|171,172|174,174|178,178|180,180|185,188|194,195|198,198|200,200|215,224|229,233|235,236|242,245|250,253|257,258|264,264|266,267|269,272|291,291|316,318|321,322|338,338|343,345|350,350|368,368|373,373|386,390|392,394|396,407|415,415|417,418|421,421|424,424|426,430|540,540|546,548|564,564|570,571|573,578|580,588|605,605|609,618|620,626|638,639|641,641|644,645|647,648|650,650|652,652 GGGGSS???EEE??S-SS?T-------TS?--EEE-EEEGGGS--T-TS--BTHHHHH---HHHHHH----------HHHTT??------------------?TT?--E-E---EEE??HH--------------------------------------HHHHHHHHHH--HH-T--?E-E----EEEE-----ES?-S?H--------------HHHHHHHHTT?---EEEEE?GG-----GHHH----HHHH---HH-----H-HH-HHHH----------------??B?????-------????????????HHH--HH---------------H----HHH----T-----------------T???-E------------EEEEG-GGT-HHHHHHHHHHHH-------H?TT?-E--E-EEEEE--???-----???----????-----------------??---------?-------------?--------???-???????-------------------???????S----?SEE---------------E-----EE?HHHHHH-HHHHHHHHH------------?-??B--?HHHHHHHHHH-HHHHHHH----------?TT?E--EE-EE-E?B 1Z7W|A PF00292.13_PAX_seed 6 126 !Q:0,3|5,5|9,9|11,12|16,18|33,34|44,45|61,72|74,74|77,77|91,91|94,95|110,110|115,116 Q:4,4|6,8|10,10|13,15|19,32|35,43|46,60|73,73|75,76|78,90|92,93|96,109|111,114|117,125 ????B?TTS?B??TTS???HHHHHHHHHHHHTT??HHHHHHHHT??HHHHHHHHHHHHHHS????????????S-SS?HHHHHHHHHHHHH?TT??HHHHHHHHHHTTSS?TTTS??HHHHHHHHH 1K78|A PF00293.23_NUDIX_seed 197 286 !Q:0,0|10,10|13,32|40,92|95,95|100,101|103,103|106,106|110,143|155,156|158,164|177,177|181,181|183,218|229,229|232,239|241,249|258,258|270,270|273,278 Q:1,9|11,12|33,39|93,94|96,99|102,102|104,105|107,109|144,154|157,157|165,176|178,180|182,182|219,228|230,231|240,240|250,257|259,269|271,272|279,285 ?EEEEEEEEB?TT?------------------?EEEEEES????------------------------------------------???????EE?SEEE??T-TS?HHH----------------------------------HHHHHHHHHHS??E-------EEEEEEEEEEEE?TTS?E------------------------------------EEEEEEEEEE?SS????????S---------SEEEEEEE?HHHHHHHHHTT?BS-----?THHHHHH 3L85|A PF00294.19_PfkB_seed 64 388 !Q:0,1|7,9|11,12|19,19|22,29|32,32|35,35|37,37|46,46|60,64|92,92|101,104|112,112|115,116|118,118|125,125|131,132|134,145|158,159|165,165|169,171|187,191|196,198|200,211|216,216|219,219|223,225|235,247|264,267|274,274|277,280|282,282|288,304|312,324|326,327|344,353|355,356|380,380|382,386 Q:2,6|10,10|13,18|20,21|30,31|33,34|36,36|38,45|47,59|65,91|93,100|105,111|113,114|117,117|119,124|126,130|133,133|146,157|160,164|166,168|172,186|192,195|199,199|212,215|217,218|220,222|226,234|248,263|268,273|275,276|281,281|283,287|305,311|325,325|328,343|354,354|357,379|381,381|387,387 ??EEEEE???E--EEEEEE?SS??-----?TT?EE-E?SEEEEEEE?HHHHHHHHHHHHT----?EEEEEEEEESSHHHHHHHHHHHHTTEE?TTEEEETT-???EEEEEEE?TT--S?EEEEEE?GGGGG??H------------HHHHTTHHHHHT?-SEEEE?SSS?--HHHHHHHHHHHHHTT----?EEEE???S-------?????HHHH-TT?SEE???HHHHHHHHS???---------?SHHHHHHHHHHHHHTT?---SEEEEE?GG----G?EEEEE-----------------TTEEEEE???--?-??????T--THHHHHHHHHHHHHTT----------T??HHHHHHHHHHHHHHHTTSSSSGG-G-?-??H 2AFB|A PF00295.12_Glyco_hydro_28_seed 16 390 !Q:0,0|8,8|11,11|13,14|16,17|21,21|23,30|33,33|44,57|59,65|74,74|79,79|82,83|87,88|91,98|101,102|104,104|106,110|115,119|127,127|134,134|138,139|142,143|148,149|157,157|161,161|169,178|180,181|186,186|188,188|196,196|200,200|203,203|212,217|224,224|230,233|240,240|244,246|270,270|273,274|276,277|307,307|311,311|313,316|334,334|344,345|349,349|363,363|365,367|369,370|372,373|376,384|387,389 Q:1,7|9,10|12,12|15,15|18,20|22,22|31,32|34,43|58,58|66,73|75,78|80,81|84,86|89,90|99,100|103,103|105,105|111,114|120,126|128,133|135,137|140,141|144,147|150,156|158,160|162,168|179,179|182,185|187,187|189,195|197,199|201,202|204,211|218,223|225,229|234,239|241,243|247,269|271,272|275,275|278,306|308,310|312,312|317,333|335,343|346,348|350,362|364,364|368,368|371,371|374,375|385,386 ?SEEEEES?EE?T--T??EEE?S??------TT?EEEEESEEEE?----------???S???----SEEEEEES?EEEE?TT-?EEE??GG--------GT??S?T-----TSSS?????EEEEEEE-TEEEES?EEE??SS??EEEE-?SSEEEES?EEE?GGGGTTT?--------?S??SEEE?S?EEEEEES?EEE?SS?SEEESSEE------EEEEES?EEESS??--EEEEEE?SSS?-?EEEEEEEEEEEEEEEEEEEEEEE-ET--T??EEEEEEEEEEEEEEEEEEEEEEEEEEEET-TEE?S??-?SSEEEEEEEEEEEEEEE?TTSEEEEEE??TTT-EEEEEEEEEEEES-S---B??S??BS??-------TT??? 1IA5|A PF00296.15_Bac_luciferase_seed 155 550 !Q:1,10|14,15|18,18|29,38|41,43|55,56|60,60|62,62|68,69|74,99|109,109|112,112|115,115|122,122|126,127|129,133|146,146|151,156|158,158|160,160|165,170|174,176|181,185|187,197|217,220|223,246|248,248|252,252|255,257|260,286|290,291|294,295|301,316|318,320|325,325|328,328|339,339|346,362|376,376|381,391|394,402|407,407|415,418|429,434|442,442|448,455|462,491|508,511|514,514|516,516|519,521|524,524|528,528|531,533|540,541|547,548 Q:0,0|11,13|16,17|19,28|39,40|44,54|57,59|61,61|63,67|70,73|100,108|110,111|113,114|116,121|123,125|128,128|134,145|147,150|157,157|159,159|161,164|171,173|177,180|186,186|198,216|221,222|247,247|249,251|253,254|258,259|287,289|292,293|296,300|317,317|321,324|326,327|329,338|340,345|363,375|377,380|392,393|403,406|408,414|419,428|435,441|443,447|456,461|492,507|512,513|515,515|517,518|522,523|525,527|529,530|534,539|542,546|549,549 E----------EEE??TT?EESSTTSSTT----------EE???HHHHHHHHHHH--HHH-T?SEEEE??STTS------------------------??HHHHHHTTS-TT?SS?EEEEEE?TTT--S----?HHHHHHHHHHHH-HHTT------S?E-EEEE??-???HHH---HHHH-----T?-------???TTHHHHHHHHHHHHHHHHT----TT----------------------??E-EEE?SS--?EE---------------------------EEE??SS??SSSSS----------------S?--EEEE?SS-HHHHHHHHHH?SEEEEE?--------------??HHHHHHHHHHHHH-HHHT-----------TT?------??EEEE-EEEEEEE----SSHHHHHHHH------HHHTTTS?HHHHH--------HHHHHS??????????????????--------??--TTEEETTEEGGGGSSS----SS?S?EE---EE-EHH-HH---HHHHHH--HHTTT??E 3RAO|A PF00297.17_Ribosomal_L3_seed 13 307 !Q:10,12|18,18|20,20|31,33|57,57|59,61|66,71|74,75|77,90|106,108|111,111|117,118|124,125|127,132|138,138|155,156|158,158|160,160|165,166|169,172|177,178|184,184|190,195|202,203|206,207|209,209|212,213|217,217|219,220|224,226|231,232|238,240|246,252|255,259|262,267|270,270|272,273|275,277|283,285|287,287|294,295|298,298|301,301|305,306 Q:0,9|13,17|19,19|21,30|34,56|58,58|62,65|72,73|76,76|91,105|109,110|112,116|119,123|126,126|133,137|139,154|157,157|159,159|161,164|167,168|173,176|179,183|185,189|196,201|204,205|208,208|210,211|214,216|218,218|221,223|227,230|233,237|241,245|253,254|260,261|268,269|271,271|274,274|278,282|286,286|288,293|296,297|299,300|302,304 EEEEEEEEEE???TTSTT?S?EEEEEEEEEE???BEEEEEEEEEEETTEEEEEEEEE?S???GGGG??????SS??S-?????????????HHHHHHHHHHHHHHS???SS?EEEEE??GGGSS-?S??????EEEEB?SSSHHHHHHHHHHHHH--S?B?STTT??SS????EEEE??EEEEE?HHHHH??????SSTTTT--TT??S?SS?-SSS?S??TTS???EEEE??EEEES???EEEEE?-?????SS?????TT??????SS?S??S???BTTTB???S?EEEEES??SS?TT?EEE?? 2ZJQ|B PF00298.14_Ribosomal_L11_seed 171 103 !Q:0,3|14,20|22,29|31,31|34,35|38,49|53,55|58,59|73,73|76,79|83,83|102,102 Q:4,13|21,21|30,30|32,33|36,37|50,52|56,57|60,72|74,75|80,82|84,101 ????HHHHHHHHHT?------S--------S?SS--ST------------TTS?-?EE??TTHHHHHHHHHTT-TS----STT?HHHHHHHHHHHHHHSSEE? 2ZJQ|F PF00299.13_Squash_seed 12 30 !Q:0,3|5,7|9,9|19,20|22,22|26,26|29,29 Q:4,4|8,8|10,18|21,21|23,25|27,28 ????S???B?SSGGGSSTT??B?TTS-BB? 2LET|A PF00300.17_His_Phos_1_seed 267 496 !Q:6,19|22,51|54,59|64,84|88,101|103,103|115,115|118,123|126,173|176,177|180,186|190,190|199,202|206,206|210,239|241,241|243,300|304,304|308,310|312,316|318,321|324,328|330,330|332,332|341,341|343,358|367,373|377,379|381,418|421,428|435,435|447,472|474,474|477,477|480,483|488,488|496,496 Q:0,5|20,21|52,53|60,63|85,87|102,102|104,114|116,117|124,125|174,175|178,179|187,189|191,198|203,205|207,209|240,240|242,242|301,303|305,307|311,311|317,317|322,323|329,329|331,331|333,340|342,342|359,366|374,376|380,380|419,420|429,434|436,446|473,473|475,476|478,479|484,487|489,495 EEEEEE???-----------BH------------------------------HH------HTTB-------------------??TTS?-----?-?-----B?HHHHHHHHHHH-HH------TT------------------------------------------------TS??SE-------EEE?SSHHHHHH----HHH-HHT------------------------------T?S--------------------------------------------------------??EEE?GGG---S????-G----GG-----T-T?BHHHHHHH?H----------------HHHHHHHH------?GGG???S--------------------------------------SS?------?HHHHHH-HHHHHHHHHHH--------------------------H?TT?EE----EEEE?HHHHHHH- 1UJC|A PF00301.15_Rubredoxin_seed 43 52 !Q:6,7|9,10|17,17|24,24|27,28|33,33|36,36|38,38|42,45|47,47 Q:0,5|8,8|11,16|18,23|25,26|29,32|34,35|37,37|39,41|46,46|48,51 EEEETT--T??EEETTT?BGGGTB?TT??GGGS?TT?B?TTT--??B-GGGE 2M4Y|A PF00302.13_CAT_seed 12 206 !Q:0,0|2,3|6,6|10,10|24,25|35,35|47,48|64,64|75,75|80,80|82,83|102,105|125,127|132,135|147,149|151,156|158,159|162,165|171,172|175,175|178,178|192,193 Q:1,1|4,5|7,9|11,23|26,34|36,46|49,63|65,74|76,79|81,81|84,101|106,124|128,131|136,146|150,150|157,157|160,161|166,170|173,174|176,177|179,191|194,205 ?S??BB?STT?TTTTHHHHTTTTS??EEEEEEEEE?HHHHHHHHHSS??HHHHHHHHHHHHHTT?GGGGEEESSS-SEEE?S??EEEEEEEETTTTEEEEEE????SSHHHHHHHHHHHHHHHTT???SSSS?-??SSEEEEEEETT???S??????S??TT????EEEEE??EE?SS?EEEEEEEEEETTT??HHHHHHHHHHHH 1QCA|A PF00303.14_Thymidylat_synt_seed 141 629 !Q:12,18|21,21|25,34|36,36|40,40|42,44|48,48|52,53|60,60|64,92|96,101|112,112|117,118|125,129|132,132|134,135|138,138|142,154|164,188|200,200|210,218|227,230|233,233|235,273|276,276|279,279|289,289|292,300|303,303|305,306|310,322|327,333|336,336|339,340|351,379|381,382|385,415|433,433|451,455|457,462|478,527|533,534|537,537|544,551|556,560|562,565|567,576|580,585|591,592|596,628 Q:0,11|19,20|22,24|35,35|37,39|41,41|45,47|49,51|54,59|61,63|93,95|102,111|113,116|119,124|130,131|133,133|136,137|139,141|155,163|189,199|201,209|219,226|231,232|234,234|274,275|277,278|280,288|290,291|301,302|304,304|307,309|323,326|334,335|337,338|341,350|380,380|383,384|416,432|434,450|456,456|463,477|528,532|535,536|538,543|552,555|561,561|566,566|577,579|586,590|593,595 HHHHHHHHHHHH-------HH?EEE----------E?TTS?E---EEE-EEE--EEEEEE-GGG?-----------------------????-SSS---???HHHHHHHHHH-HHTT??BTHHHH-----HT-T??TT?HHH-------------HHHHHHSSS?????????????????????????HHHHHHHHHHH?HHHHHHHSB?-------?SSHHHHHH?---EE?T---------------------------------------TS?EE?HHHHHHHHH-HH--------?TT?S??EEE?----------??TTTG-------GG?SS??SEEEEEEEEE-----------------------------T--TE-------------------------------EEEEEEEEEEETTTHHH-HHHHHHHHHHHHHHHHT-----T-----?EEEEEEEEEEEEEEE--------------------------------------------------GGGHH--HH-HHHHTS--??????EEEE----?T----T??-------?GGG?----?GGGEE--EES?????-???-------------------????? 3UM8|A PF00304.15_Gamma-thionin_seed 50 59 !Q:0,0|6,6|10,10|14,14|16,16|20,21|29,30|34,37|44,46|50,51|58,58 Q:1,5|7,9|11,13|15,15|17,19|22,28|31,33|38,43|47,49|52,57 ?EEEEE?SSS-SSS?S?HHH--HHHHHHH--HSS?---EEEEST---TTS?-EEEEEE? 2E3F|A PF00305.14_Lipoxygenase_seed 16 696 !Q:0,0|16,20|22,22|24,26|29,33|36,36|38,39|41,42|46,46|50,53|61,64|67,71|73,73|76,76|81,88|91,94|99,101|107,107|127,127|134,134|137,138|150,150|152,158|175,175|177,178|182,185|188,191|197,197|216,216|219,220|223,224|228,233|241,245|250,251|254,258|267,267|287,287|290,290|292,293|302,302|306,306|315,315|319,319|326,327|333,336|384,384|401,401|430,430|441,443|462,462|475,476|501,501|510,510|531,531|535,536|576,579|582,585|591,593|600,600|610,611|627,627|629,629|632,633|638,639|642,645|647,647|674,674|677,677|679,679|687,690|693,693|695,696 Q:1,15|21,21|23,23|27,28|34,35|37,37|40,40|43,45|47,49|54,60|65,66|72,72|74,75|77,80|89,90|95,98|102,106|108,126|128,133|135,136|139,149|151,151|159,174|176,176|179,181|186,187|192,196|198,215|217,218|221,222|225,227|234,240|246,249|252,253|259,266|268,286|288,289|291,291|294,301|303,305|307,314|316,318|320,325|328,332|337,383|385,400|402,429|431,440|444,461|463,474|477,500|502,509|511,530|532,534|537,575|580,581|586,590|594,599|601,609|612,626|628,628|630,631|634,637|640,641|646,646|648,673|675,676|678,678|680,686|691,692|694,694 ?GGGHHHHHHHHHHHH?---?S?S???TT?????EE?B??S??GGG?GGG????BSSSSSS????EE?????B?SS?TTSB??-----?SS????GGGS???SSGGG?HHHHHHHHHHTHHHHHHHH-HTTTSS?SS??SHHHHHGGGTT?B???----HHHHHHHTTSTTHHHH?B??SSS---?BB????GGGTS?SSGGGSHHHHHHHHHHSS?TT??EE??SSS??????SSSTTTS?????SGGG??SS??-??HHHHHHTT?EEEEEESTTTGGGHHHHTT-SS?B??EEEEEEEE?TTS?EEEEEEEE-EES?SSSGGG??EEEEE????SHHHHHHHHHHHHHHHHHHHHHHHHIIIIITTHHHHHHHHHHHHHHS?TTSHHHHHHGGGGTTH-HHHHHHHHHHTSSTTSHHHHHSTTGGGH-HHHHHHHHTT-??GGGGSHHHHHHHTTSEEE?TTSTTSEEESSS??HHHHHHHHHHHHHHHHHHHHHHHH?SSHHHHHT?HHHHHHHHHHHHTTTGGGTT?TTS??SSSHHHHHHHHHHHHHHHTHHHHHHHTTHHHHHSSTTTS????BS????TTSHH---HHHHHH?HHHHHHHHS??HHHHHHHHHHHHHHT?B?TT??BTTT??SS?-??S?HHHHHHHHHHHHHHHHHHHHHHHHHT?TT?G-GGTTTTT????TT?S?- 3FG1|A PF00306.22_ATP-synt_ab_C_seed 150 194 !Q:10,13|26,29|31,32|34,34|38,40|44,44|47,49|51,53|56,57|59,59|66,66|69,76|82,82|85,85|87,125|129,131|137,141|143,143|149,149|155,155|160,160|163,163|165,167|173,184|190,193 Q:0,9|14,25|30,30|33,33|35,37|41,43|45,46|50,50|54,55|58,58|60,65|67,68|77,81|83,84|86,86|126,128|132,136|142,142|144,148|150,154|156,159|161,162|164,164|168,172|185,189 HHHHHHHHHH----HHHHHHHHHHHH----H--H?STT?-?TTT-TH---H---HH--H-HHHHHH-HT??----??GGGTT-TS?S??????---------------------------------HHH---HHHHH-----H-HHHHT-TTTTS?GGGS-TT?S---SHHHH------------HHTTT??-- 3OAA|A PF00307.26_CH_seed 194 235 !Q:9,9|14,15|17,83|86,97|100,100|118,119|121,123|126,137|141,144|146,151|153,164|175,177|184,188|190,198|206,207|210,211|214,220 Q:0,8|10,13|16,16|84,85|98,99|101,117|120,120|124,125|138,140|145,145|152,152|165,174|178,183|189,189|199,205|208,209|212,213|221,234 HHHHHHHHH-HHHT--T?------------------------------------------------------------------TT?-???-------SS-SGGGTTSHHHHHHHHHH-?T---TS---------?-?GGG?--?T------T-----------?HHHHHHHHHH---HHHHHS?????S--------?HHHHHHS--SS??HH-------HHHHHHHHHHHHHH 3F7P|A PF00308.13_Bac_DnaA_seed 14 234 !Q:0,1|4,4|9,12|29,29|33,34|36,37|42,42|63,65|68,68|88,89|91,91|103,103|110,110|117,117|136,136|145,145|149,149|152,153|165,166|168,172|186,189|193,201|212,213|215,215 Q:2,3|5,8|13,28|30,32|35,35|38,41|43,62|66,67|69,87|90,90|92,102|104,109|111,116|118,135|137,144|146,148|150,151|154,164|167,167|173,185|190,192|202,211|214,214|216,233 ??TT?SGGG????TTTHHHHHHHHHHHHS-TTS--S??EEEE?SSSSSHHHHHHHHHHHHHHH??-SS?EEEEEHHHHHHHHHHHHHT--T?HHHHHHHHTTT?SEEEEE?GGGGSS?HHHHHHHHHHHHHHHTTT?EEEEEESS?GGG?SS??HHHHHHHHSSB??B?????HHHHHHHHHHHHH----HHT??-----??TTHHHHHHHH??S?HHHHHHHHHHHHHHHHHS 3BOS|A PF00310.16_GATase_2_seed 57 614 !Q:0,0|3,3|8,8|12,14|16,16|34,34|36,36|50,51|53,54|59,59|67,67|69,73|75,75|78,79|86,86|95,98|112,112|120,122|124,124|129,129|133,134|138,139|148,148|151,179|193,193|198,203|205,205|209,219|237,237|245,245|254,256|264,266|270,272|279,279|281,289|296,297|299,299|309,310|316,319|324,326|334,335|337,338|341,465|467,467|476,476|485,487|497,501|504,504|509,509|511,511|521,522|527,533|535,535|541,544|546,553|556,558|560,561|567,567|570,572|574,578|583,583|585,598|601,606 Q:1,2|4,7|9,11|15,15|17,33|35,35|37,49|52,52|55,58|60,66|68,68|74,74|76,77|80,85|87,94|99,111|113,119|123,123|125,128|130,132|135,137|140,147|149,150|180,192|194,197|204,204|206,208|220,236|238,244|246,253|257,263|267,269|273,278|280,280|290,295|298,298|300,308|311,315|320,323|327,333|336,336|339,340|466,466|468,475|477,484|488,496|502,503|505,508|510,510|512,520|523,526|534,534|536,540|545,545|554,555|559,559|562,566|568,569|573,573|579,582|584,584|599,600|607,613 ?EE-EEEE?SSS???S-HHHHHHHHHHHTTGGGS?B?TTSSEEEEEEEEE--E??TTTT-HHHHHHT-T?????G-GG??EEEEEE?SSHHHHHH----HHHHHHHHHHHTT?EEEEEEE-??B?GGGS?HHH--HHH??EEEEEEEE?TT?--------------------------??HHHHHHHHHHHHH-HGGG------G?BTT-----------BEEEEEESSEEEEEEEE?GGGHHHH-BSGGGSTT???SEEEEEE???SSS???GGGSSS?S---------SEEEEE??S?HHHHHHHHH--TTSTT?--?BTTB?--HHHHTTS??S??TT-----------------------------------------------------------------------------------------------------------------------------S?HHHHHHHH-HHHHHHTT-??HHHHHHHHS????-SS?GGGT-T?HHHHHHHHH--HHHH?????--S?EEEEE----E---?----SS---B--EEEEE?TT??-S---??EEEE-E--------------TT?---?-EEEESST 3OOJ|A PF00311.12_PEPcase_seed 65 997 !Q:1,1|8,10|13,16|35,35|38,39|44,60|77,82|84,86|118,121|126,127|129,131|133,140|142,144|150,150|155,155|158,158|162,162|192,202|215,242|245,245|273,293|296,296|301,302|323,323|371,378|383,383|397,397|400,409|411,417|419,427|444,448|460,461|473,475|481,483|486,503|510,510|538,568|575,575|584,584|607,610|612,612|619,619|627,627|632,632|640,640|645,645|654,654|684,685|688,700|725,725|749,749|752,764|769,769|782,783|799,801|804,804|807,811|823,823|840,841|854,855|858,858|862,864|886,886|893,893|896,907|935,935|938,976|993,997 Q:0,0|2,7|11,12|17,34|36,37|40,43|61,76|83,83|87,117|122,125|128,128|132,132|141,141|145,149|151,154|156,157|159,161|163,191|203,214|243,244|246,272|294,295|297,300|303,322|324,370|379,382|384,396|398,399|410,410|418,418|428,443|449,459|462,472|476,480|484,485|504,509|511,537|569,574|576,583|585,606|611,611|613,618|620,626|628,631|633,639|641,644|646,653|655,683|686,687|701,724|726,748|750,751|765,768|770,781|784,798|802,803|805,806|812,822|824,839|842,853|856,857|859,861|865,885|887,892|894,895|908,934|936,937|977,992 T?EEEEEE???TT????HHHHHHHHHHHHHHHHHT?SS??HHHH-----------------HHHHHHHHHHHHHHHT??????S???HHHHHHHHTHHHHHTHHHHHHHHHHHHHHHH----HHTT??S???T--------T???EEEEE?TTTB?TT?TTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHH???----????HHHHHHHHHHHH-----------?????????????????TT?HHHHHHHHHHHHHHHHHHHHHHHHHHS-------------------??SS?GGGS??SHHHHHHHHHHHHHHHHHTT?HHHHTTHHHHHHHHHHHHTTSSSEEEEEEEHHHHHHHHHHHHHHTTS------??TTTS?HHHHHHHHHHHHT?SS?-?-----??T-------T?-----???HHHHHHHHHHHHHHHS-?---GGGEEEEEEET??SHHHHHHHHHH---HHHTT?--SS?----------------?EEEEEE?SHHHHHHHHHHHHHHHTSHHHHHHHTT-------------------------------EEEEEE?HHHHHHHH?HHHHHHHHHHHHHHHHHHHHHH----T?EEEEEE?TTSGGGS?SHHH-HHHHHTS?TTSS-TTEEEEEE?TTTHHHHHSSHHHHHHHHHHHHHHHHHHH--HS??????-------HHHHHHHHHHHHHHHHHHHHHHTT?TTHHHHHHHHSSHHHHHHTTSSS?SB??----??--???TTTB?HHHHHHHHHTTT??HHHHTTHHHHHHHHH---HH?TH-----HHHHHHHHHHH?HHHHHHHHHHHHHHHT??HHHHHHHHHHHS-?GG-GHH---HHHHHHHHHHHHHHHHHHHHT?SSTTTT?HH------------HHHHHHHHHHHHHHHHHHHHHHHHHHH?TT?---???????????????????????????????????HHHHHHHHHHHHHHHH????- 3ZGB|A PF00312.17_Ribosomal_S15_seed 9 88 !Q:10,11|13,17|40,40|43,44|68,73|86,87 Q:0,9|12,12|18,39|41,42|45,67|74,85 HHHHHHHHHT??S?????SHHHHHHHHHHHHHHHHHHHHH?TT??HHHHHHHHHHHHHHHHHHHHHHH?-----HHHHHHHHHHHT?? 3KIX|o PF00313.17_CSD_seed 40 74 !Q:18,18|21,21|23,25|29,29|33,35|38,47|50,50|59,60|73,73 Q:0,17|19,20|22,22|26,28|30,32|36,37|48,49|51,58|61,72 EEEEEEEEETTTTEEEEE?SS?S--?EEE?TTS???TT-----?????TT?EEEEEEEE--ETTEEEEEEEEE? 2K5N|A PF00314.12_Thaumatin_seed 124 389 !Q:1,1|5,5|13,16|18,29|35,35|38,38|40,41|46,50|53,56|69,69|71,83|86,86|94,97|99,100|105,105|107,107|109,113|116,117|124,133|139,143|151,152|155,155|159,159|166,179|184,189|193,193|195,232|237,238|244,262|264,280|284,285|288,298|301,305|307,308|313,316|320,334|344,346|351,351|355,356|359,362|367,371|373,373|375,378|384,388 Q:0,0|2,4|6,12|17,17|30,34|36,37|39,39|42,45|51,52|57,68|70,70|84,85|87,93|98,98|101,104|106,106|108,108|114,115|118,123|134,138|144,150|153,154|156,158|160,165|180,183|190,192|194,194|233,236|239,243|263,263|281,283|286,287|299,300|306,306|309,312|317,319|335,343|347,350|352,354|357,358|363,366|372,372|374,374|379,383 E?SSS?EEEEEET----T------------EEEEE?TT?E--EEEE---??TT--??SEEEEEEEEEEE?T-------------TS-BEEEEES??--T--TBSS?S-S-?-??SS??EEEEEE----------EETTT-----EEEEEEE-?TT?BSS?EEEEES--------------SSSS----??EEE?S-------------------------------------?HHHH??TTTEE-------------------T-----------------TEE??HH-----------HH-----H??HHHH?---TTS?------??----??HHHHHHHHH?--TTEE?STT??SS??--EEEE-----T-T-??-EEEEE--?-? 2WBZ|A PF00316.15_FBPase_seed 12 356 !Q:0,0|13,13|15,15|17,18|21,25|48,72|86,87|98,98|101,103|106,106|109,110|128,129|139,139|142,153|157,159|164,166|170,170|191,193|214,216|218,220|224,225|233,233|246,246|252,252|255,255|258,260|262,262|274,276|281,283|286,288|291,291|311,311|318,318|322,323|326,329|333,333|335,336 Q:1,12|14,14|16,16|19,20|26,47|73,85|88,97|99,100|104,105|107,108|111,127|130,138|140,141|154,156|160,163|167,169|171,190|194,213|217,217|221,223|226,232|234,245|247,251|253,254|256,257|261,261|263,273|277,280|284,285|289,290|292,310|312,317|319,321|324,325|330,332|334,334|337,355 ?BHHHHHHHHHTT?T-T??SH-----HHHHHHHHHHHHHHHHHHHTTS?????????????????????????HHHHHHHHHHTTT??SEEEESSSSS?EE?--TT?TT??EEEEEEEEETGGGGGGT??EEEEEEEEE?SS?-----------TTS???HHHH???GGG?SEEEEEEESSSEEEEEESSS--?EEEEEEETTTTEEEEEEEEE???S???EEE??GGGGGGS?HHHHHHHHHHHS?BGGGT-BS?EE???S?HHHHHHHHHHH?-?EEEE???SS--?TT?SSBTTTTHHHHHHHHHHTT?EEESSS-SBG--GG????STT?B??EEEESHHHHHHHHHHHHHS 1DCU|A PF00317.16_Ribonuc_red_lgN_seed 137 180 !Q:3,3|9,9|12,12|18,20|24,26|28,31|33,36|38,40|55,138|140,140|146,149|153,156|167,167|179,179 Q:0,2|4,8|10,11|13,17|21,23|27,27|32,32|37,37|41,54|139,139|141,145|150,152|157,166|168,178 TTS?HHHHH-HH-HHHTS?--BSS---S----S----B???HHHHHHHHHHHHHT------------------------------------------------------------------------------------T?HHHHH----HHH----HHHHTTSEEE?HHHHHHTTSSS? 3O0Q|A PF00318.15_Ribosomal_S2_seed 177 357 !Q:0,1|4,4|6,6|8,11|13,19|22,23|27,27|29,30|32,32|34,40|42,44|47,48|50,50|54,54|72,72|75,149|153,154|157,159|162,163|175,180|184,184|187,193|195,198|218,222|232,238|241,241|243,243|267,267|270,273|275,282|287,287|289,292|307,308|310,316|320,320|324,327|330,334|336,337 Q:2,3|5,5|7,7|12,12|20,21|24,26|28,28|31,31|33,33|41,41|45,46|49,49|51,53|55,71|73,74|150,152|155,156|160,161|164,174|181,183|185,186|194,194|199,217|223,231|239,240|242,242|244,266|268,269|274,274|283,286|288,288|293,306|309,309|317,319|321,323|328,329|335,335|338,356 ??TT?S?S-??-S------?TT??TTS?T--T-B???-?--S---SS??B?GGG-THHHHHHHHHHHHHHHT-TT--------------------------------------------------------------------??----?EEE??SH---HH--HTTTHHHHTTT------TSE-EE-?-----S??-?TTSSSSHHHHHHHHHHHHH-----HHHHHHSGG-------GS?S?HHHHHHHHHHHHHHHHHTTTTTT?SS?--?S----?---EEES?T----TTTHHHHHHHHHHT??B?--????TTS?GGG---?SS?????S??HHHHHHHHHHHHHHHHTTT 3KIX|b PF00319.13_SRF-TF_seed 10 51 !Q:1,3|32,32|40,40|43,44|50,50 Q:0,0|4,31|33,39|41,42|45,49 S???SHHHHHHHHHHHHHHHHHHHHHHHHHHT?EEEEEEE?TT??EEEEE? 1MNM|A PF00320.22_GATA_seed 69 44 !Q:0,0|2,3|6,7|9,12|14,14|18,18|20,21|23,24|26,28|43,43 Q:1,1|4,5|8,8|13,13|15,17|19,19|22,22|25,25|29,42 ?T--TT??S?--?S?EEE?S--S??E---EEHHHHHHHHHTSS? 4GAT|A PF00321.12_Thionin_seed 37 48 !Q:0,0|3,3|20,22|32,32|35,35|40,41|45,47 Q:1,2|4,19|23,31|33,34|36,39|42,44 ?EE?SSHHHHHHHHHHHHTT?-?HHHHHHHHT?EE?SSSS??TTS?-? 1CRN|A PF00322.12_Endothelin_seed 8 31 !Q:0,7|11,11|23,25|27,30 Q:8,10|12,22|26,26 -----???SSS?HHHHHHHHHHT???S??-- 1T7H|A PF00323.14_Defensin_1_seed 11 30 !Q:0,0|6,9|12,13|29,29 Q:1,5|10,11|14,28 ?EEESS-???TT??EEEEEEETTEEEEEE? 3HJD|A PF00324.16_AA_permease_seed 26 599 !Q:12,13|27,27|30,31|33,34|39,39|60,67|80,80|82,82|92,97|121,121|134,151|166,166|177,178|195,198|202,203|212,235|238,238|240,247|263,263|265,265|301,320|331,331|338,338|340,372|383,383|423,428|433,435|439,440|456,463|465,465|469,477|500,508|515,527|548,553|560,563|589,591|594,598 Q:0,11|14,26|28,29|32,32|35,38|40,59|68,79|81,81|83,91|98,120|122,133|152,165|167,176|179,194|199,201|204,211|236,237|239,239|248,262|264,264|266,300|321,330|332,337|339,339|373,382|384,422|429,432|436,438|441,455|464,464|466,468|478,499|509,514|528,547|554,559|564,588|592,593 HHHHHHHHHHHT--TTTTTHHHHHTTT?TT--H--HHHH-HHHHHHHHHHHHHHHHHHHH??-----?TTTHHHHHHHHH?H-HHHHHHHHH------HHHHHHHHHHHHHHHHHHHGGGT?GGGTSHHHHHHH------------------HHHHHHHHHHHHHT?HHHHHHHHHH--HHHHHHHHHHHHHHHG----GGG??HHHHHHTS-----------------------?TT?S-------?HHHHHHHHHHHHGGG?T-TTTHHHHGGGGBSSHHHHHHHHHHHHHHHHHHHHH--------------------HHHHHHHTTS?HHHHHT?S--------------------------------?HHHHHHHHHT?SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSS?-----GGGG???TTS??HHHHHHHHHHHHHHH--------H-TTS?????????HHHHHHHHHTHHHHHHHHHHHH---------HHHGGG-------------GGGGHHHHHHHHHHHHHHHH------HHHHTS?---HHHHHHHHHHHHHHHHHHHHHHTTT???SS????? 3GIA|A PF00325.15_Crp_seed 12 34 !Q:2,5|16,16 Q:0,1|6,15|17,33 EE??--HHHHHHHHTS?HHHHHHHHHHHHHTTSE 1ZRD|A PF00326.16_Peptidase_S9_seed 70 275 !Q:0,10|18,31|35,35|41,42|46,46|49,49|77,82|87,88|90,91|113,113|115,115|119,119|127,130|137,137|141,143|154,155|157,157|159,160|172,172|177,178|180,187|189,191|201,201|205,205|207,207|220,226|228,229|231,233|242,243|245,247|249,250|273,274 Q:11,17|32,34|36,40|43,45|47,48|50,76|83,86|89,89|92,112|114,114|116,118|120,126|131,136|138,140|144,153|156,156|158,158|161,171|173,176|179,179|188,188|192,200|202,204|206,206|208,219|227,227|230,230|234,241|244,244|248,248|251,272 ???------?-GGGHHHH--------------TTT?EEEEE??TTS?TT?THHHHTTSSGGGTHHHHHHHHHHHHHH------HHTT--S??GGGEEEEEETHHHHHHHHHHH-H?GGG?SEEEEES????HHHHHT?TTS---TTHHHHTTTT??T-T--SHHHHHHHHHH?TGGG??S--------S???EEEEEEETT?SSS?T-HHHHHHHHHHHH-------H??S???EEEEEETT??S---S??SSHHHHHHHHHHHHHHHHHHTT?? 1TQH|A PF00327.15_Ribosomal_L30_seed 115 67 !Q:0,0|4,10|12,14|17,17|28,29|35,35|39,41|43,43|47,55|59,59|66,66 Q:1,3|11,11|15,16|18,27|30,34|36,38|42,42|44,46|56,58|60,65 ?EEE?????-?T---TS?HHHHHHHHHS??SSSSS?EEE???S-HHH---------HHH-HHTGGG? 2ZJQ|W PF00328.17_His_Phos_2_seed 93 924 !Q:10,11|14,16|33,104|106,106|108,110|119,203|207,217|219,219|222,222|236,236|241,257|263,274|301,320|322,322|325,332|339,343|347,348|352,364|370,392|411,418|425,458|462,469|486,511|517,518|520,521|527,527|529,529|531,535|544,669|676,681|686,698|704,707|727,731|735,736|739,796|805,805|807,808|816,816|826,826|829,832|838,842|846,855|862,863|869,869|872,872|880,880|882,887|889,903|906,906|908,914|916,916 Q:0,9|12,13|17,32|105,105|107,107|111,118|204,206|218,218|220,221|223,235|237,240|258,262|275,300|321,321|323,324|333,338|344,346|349,351|365,369|393,410|419,424|459,461|470,485|512,516|519,519|522,526|528,528|530,530|536,543|670,675|682,685|699,703|708,726|732,734|737,738|797,804|806,806|809,815|817,825|827,828|833,837|843,845|856,861|864,868|870,871|873,879|881,881|888,888|904,905|907,907|915,915|917,923 EEEEEEEEEE??SB???HHHHHHHHHHHHHHHH------------------------------------------------------------------------H?S???GGGGGGGT?-------------------------------------------------------------------------------?????SSS-----------B?HH-HHHHHHHHHHHHH-HHTH-----------------HHHTT---------???EEEEEESHHHHHHHHHHHHHHHHHHH--------------------T?TT????????EEEEEE?---?TTS??TTS?---------???HHHHT---------------------??HHHHHHHHHHHHHHHHHH--------HHHHHH----------------------------------STT----????HHHHHHHHHHHHHHHH--------------------------HHSTT??S??TTGGG-S?H-----HHHHHHHH------------------------------------------------------------------------------------------------------------------------------HHHHHH------HHHT-------------STTST----TTGGGGHHHHHHHHHHHHT?????SSS??HH----------------------------------------------------------HHTSTTTS?S??SEEEEEE?HHHHHHHHH-HT----TTTTT?????SSS???-------TTTTTT??HHHHS?BT?EEEEEEE-E------E---------------TT?S-------S?EEEEEET 4ARO|A PF00329.14_Complex1_30kDa_seed 131 150 !Q:9,11|13,15|24,24|27,27|30,34|44,44|46,48|54,66|74,75|77,78|80,81|83,86|90,90|105,106|108,108|111,112|114,125|128,129|132,136|138,145 Q:0,8|12,12|16,23|25,26|28,29|35,43|45,45|49,53|67,73|76,76|79,79|82,82|87,89|91,104|107,107|109,110|113,113|126,127|130,131|137,137|146,149 HHHHHHHHT---T???EEEEEEEE?TT?SS?---?SSSEEEEEE-E???TTSSS?????--------EEEEEEE-?S--S??B????TTT?STHHHHHHHHHHTS??B?TT-?S?------??-??SS?-TT---??S-------?TTST 3I9V|5 PF00330.15_Aconitase_seed 11 520 !Q:0,0|12,12|16,25|34,35|57,57|60,60|63,74|79,80|83,84|88,88|92,96|121,121|125,125|129,131|133,133|142,142|144,145|148,160|177,177|182,183|194,195|200,201|211,213|216,217|250,250|266,266|271,274|286,286|297,299|305,306|309,315|326,328|330,330|332,332|338,340|351,369|373,381|394,394|412,414|417,419|427,427|453,454|457,457|463,463|465,468|471,471|474,481|490,492|499,499|507,508 Q:1,11|13,15|26,33|36,56|58,59|61,62|75,78|81,82|85,87|89,91|97,120|122,124|126,128|132,132|134,141|143,143|146,147|161,176|178,181|184,193|196,199|202,210|214,215|218,249|251,265|267,270|275,285|287,296|300,304|307,308|316,325|329,329|331,331|333,337|341,350|370,372|382,393|395,411|415,416|420,426|428,452|455,456|458,462|464,464|469,470|472,473|482,489|493,498|500,506|509,519 ?HHHHHHHTTBS?TTT------????TTTSEEEE??SEEEEEHHHHHHHHHHHHHHT?SS?SS?-----------EEEE??TT??BSS?HHH-----HHHHHHHHHHHHHHHHHHHHHHHT?EEE?TTS---B?HHHHHHHH-T??TT?------------EEEESSTTGGGGGGGT?EEEE??HHHHHHHHHT??EEEE??EEEEEEEES???TT??HHHHHHHHHHHHHHHHTTTEEEEEESGGGGGS?HHHHHHHHHHGGGGT?SEEE????HHHHHHHHHTT?HHHHHHHHTS---GGGSS??TT?----??SEEEEEETTT???B?B?SSSTT???BHHHHHHHHH-------------------HHT??------?BEEEEEEETTTB?SHHHHHHHHHHHHHHHT---TT???SSEEEEE?SBHHHHHHHHHTSHHHHHHHTTEEE??SS?GGGTT?B?-??SS?TT------??EEEEESSS???TTSSSS?TTEEEEE??HHHHHHHHHHT 3SNP|A PF00331.15_Glyco_hydro_10_seed 54 491 !Q:0,0|9,11|18,18|22,26|29,29|31,34|42,43|46,46|61,61|66,91|93,95|110,110|115,116|122,123|125,130|136,139|143,143|148,150|180,187|195,195|197,197|200,209|213,222|230,237|253,258|269,269|274,278|281,281|294,294|298,308|313,314|317,317|322,331|347,350|360,360|363,363|366,368|372,386|391,391|412,413|417,419|434,434|440,441|445,445|449,449|452,453|457,458|465,465|468,470|474,474|480,480|489,490 Q:1,8|12,17|19,21|27,28|30,30|35,41|44,45|47,60|62,65|92,92|96,109|111,114|117,121|124,124|131,135|140,142|144,147|151,179|188,194|196,196|198,199|210,212|223,229|238,252|259,268|270,273|279,280|282,293|295,297|309,312|315,316|318,321|332,346|351,359|361,362|364,365|369,371|387,390|392,411|414,416|420,433|435,439|442,444|446,448|450,451|454,456|459,464|466,467|471,473|475,479|481,488 ?HHHHTTTT?--EEEEEE?GGG-----GG?H----HHHHHHH--HH?SEEEESSTTSHHHH?SBTT--------------------------B???HHHHHHHHHHHHTT?EEEE??SEEST--T??----GGGGB?---TTS?BGGG???HHHHHHHHHHHHHHHHHHHHHHHHHHTTT------??EEEEEES?B?TT----------SSB??-------?HHHHHHT--------THHHHHHHHHHHHHH?-----SSSEEEEEES?TTST-----TH-HHHHHHHHHHHH-HTT??-------??EEEE??EE?SSSS---?------HHHHHHHHHHHHTTT---?EEEEEEEEE?SS?SS???BSS---------------GGGS?HHHHHHHHHHHHHHHHHHHH--TTT---TEEEEEESSSSTTS?GGGGG??EEE?TTS?EE??TTS??SEEETT?SB???SSB?TTSBB?HHHHHHHS?? 1W32|A PF00332.13_Glyco_hydro_17_seed 16 333 !Q:0,0|4,7|11,13|26,27|34,35|46,47|53,55|65,65|84,84|96,97|104,108|125,125|127,127|142,143|149,149|156,159|172,173|178,179|187,187|190,190|193,193|200,200|203,204|207,208|212,213|216,217|235,235|237,237|239,240|247,249|254,256|259,260|277,280|282,283|286,287|289,292|297,297|300,301|304,305|309,312|317,318|321,321|325,325|329,332 Q:1,3|8,10|14,25|28,33|36,45|48,52|56,64|66,83|85,95|98,103|109,124|126,126|128,141|144,148|150,155|160,171|174,177|180,186|188,189|191,192|194,199|201,202|205,206|209,211|214,215|218,234|236,236|238,238|241,246|250,253|257,258|261,276|281,281|284,285|288,288|293,296|298,299|302,303|306,308|313,316|319,320|322,324|326,328 ?EEE????SSS???HHHHHHHHHHHT??EEEESS??HHHHHHTTTS??EEEEE??-GGGHHHHHH?HHHHHHHHHHHTTTTTTT-SEEEEEEEEES??GGGGGG-----HHHHHHHHHHHHHHHT?T-TSEEEEEEEGGGEE??SSGGG?EESSTH----HHHHHHHHHHHT??EEEE??HHHHHHH?TT-TS?HHHHHT?TT??EE-?TTT??EE??HHHHHHHHHHHHHHHHT?T-T??EEEEEE???SSSS---TT??HHHHHHHHHHHHTTGG----G??SS??S-???EEEE?SB??TT??SSG----GGGG??SB?TTS?BSS???? 3UR8|A PF00333.15_Ribosomal_S5_seed 13 68 !Q:0,1|10,10|15,15|18,19|22,22|31,31|46,46|62,62|65,67 Q:2,9|11,14|16,17|20,21|23,30|32,45|47,61|63,64 ??EEEEEEEE?SSSB?SS??SS?EEEEEEEE?SSSEEEEEEEEESS-HHHHHHHHHHHHTTS?EE??? 3KIX|e PF00334.14_NDK_seed 171 199 !Q:0,2|9,9|17,20|29,29|33,33|35,35|43,43|45,47|54,55|58,62|68,68|71,74|86,90|92,97|106,109|111,111|122,127|129,129|134,134|136,139|145,147|149,149|152,154|156,163|166,169|174,174|179,180|190,194|198,198 Q:3,8|10,16|21,28|30,32|34,34|36,42|44,44|48,53|56,57|63,67|69,70|75,85|91,91|98,105|110,110|112,121|128,128|130,133|135,135|140,144|148,148|150,151|155,155|164,165|170,173|175,178|181,189|195,197 ?--EEEEEE?HHHHHTT---?HHHHHHHH-HHT-T?EEEEEEE-E???HHHHHH--HT-----GGGTT-ST----THHHHHHHHTS-----S-?----EEEEEEES----T-THHHHHHHHH----??S-SGGG-S---?TTSHH---H-HH???S--------SS---?SEEE?SSHH--HHHHHHHHH??---GGG? 1XQI|A PF00337.17_Gal-bind_lectin_seed 80 265 !Q:5,6|9,12|14,16|18,18|27,44|48,67|78,87|90,90|92,92|101,101|105,112|119,120|126,127|129,134|137,194|197,201|204,204|206,206|214,215|233,233|235,236|238,238|240,241|244,245|247,247|253,254|258,258 Q:0,4|7,8|13,13|17,17|19,26|45,47|68,77|88,89|91,91|93,100|102,104|113,118|121,125|128,128|135,136|195,196|202,203|205,205|207,213|216,232|234,234|237,237|239,239|242,243|246,246|248,252|255,257|259,264 SEEEE?-TT??-?T---T?EEEEEEEE?-----------------SSS?-------------------SBEEEEEESS----------SS?S?EEEEEEEE?STT-------?EEEEEE--EETTE--E?--?-?EE----------------------------------------------------------ES?????TT?E-EEEEEEE?-SSEEEEEETTEEEEEEE?S--S?G--GG??E-EEEEE--SEE-EEEEEE 3M3O|A PF00338.17_Ribosomal_S10_seed 193 136 !Q:0,3|10,11|26,32|35,35|37,47|50,50|56,57|62,63|66,67|70,70|79,83|85,101|106,107|111,115|117,117|119,126|129,129|131,135 Q:4,9|12,25|33,34|36,36|48,49|51,55|58,61|64,65|68,69|71,78|84,84|102,105|108,110|116,116|118,118|127,128|130,130 ????EEESSH--HHHHHHHHHHHHTT------?SS-S???????????EE-EEEEE??SSSS?-TT??EE-EEEEEEEE????-S--------------???SSST--TSS-----T-T???----?TT?B????? 3KIX|j PF00339.24_Arrestin_N_seed 42 200 !Q:0,0|6,10|16,16|21,22|24,29|33,33|35,36|40,42|45,46|52,52|59,69|77,78|84,85|88,90|92,97|107,122|124,124|128,129|133,137|141,144|148,150|153,153|156,157|171,171|174,177|179,181|183,185|198,199 Q:1,5|11,15|17,20|23,23|30,32|34,34|37,39|43,44|47,51|53,58|70,76|79,83|86,87|91,91|98,106|123,123|125,127|130,132|138,140|145,147|151,152|154,155|158,170|172,173|178,178|182,182|186,197 ?EEEES----?SEEEE?SSSB??E------EEB?B??STT?--TT-?EEEEE?EEEEEE???????????EEEEEEE??EEEES??SS-??S---???HHHHHHTTS----------------S?TTB??EEE???--SSS-???EEE???SS?SS??EEEEEEEEEEEES?TT----S???S---TTEEEEEEEEEE?? 1G4R|A PF00340.14_IL1_seed 16 126 !Q:0,1|9,10|16,16|19,21|29,30|39,39|57,59|63,63|65,65|68,69|73,73|79,79|82,82|85,87|96,96|101,101|108,108|113,113|119,119|121,122 Q:2,8|11,15|17,18|22,28|31,38|40,56|60,62|64,64|66,67|70,72|74,78|80,81|83,84|88,95|97,100|102,107|109,112|114,118|120,120|123,125 ??GGGGGGS??EEEEE?SS???SSEEEEE--EEETTSSE-EEEEEESSSSEEEEEEE??-TTT?S?SS??GGG?EEEEE?SS?EE---EEESSSTT?EEEB?SSTTEE?EEES?SSSSS-B??EEE 4GAF|A PF00341.12_PDGF_seed 57 101 !Q:13,13|16,17|19,21|25,26|30,30|38,40|43,43|45,45|47,47|68,79 Q:0,12|14,15|18,18|22,24|27,29|31,37|41,42|44,44|46,46|48,67|80,100 SEEEEEEEEHHHH?TT??S?--EEE--SSE-EEEEEEE---SB?S-S-TTEEEEEEEEEEEEEEEEEE------------ETTTEEEEEEEEEEEEEEEEE 4GLN|E PF00342.14_PGI_seed 10 522 !Q:1,1|6,7|34,36|43,45|51,51|54,57|86,86|89,89|93,93|95,96|102,103|121,121|124,133|135,135|141,142|155,156|166,166|170,171|190,196|210,210|219,220|223,224|228,230|234,234|238,238|245,245|253,253|275,275|279,279|296,298|306,306|325,327|329,329|333,334|336,336|339,342|346,348|365,368|377,377|379,380|382,385|408,408|410,410|423,425|437,437|439,443|452,453|477,478|481,482|503,511|514,514 Q:0,0|2,5|8,33|37,42|46,50|52,53|58,85|87,88|90,92|94,94|97,101|104,120|122,123|134,134|136,140|143,154|157,165|167,169|172,189|197,209|211,218|221,222|225,227|231,233|235,237|239,244|246,252|254,274|276,278|280,295|299,305|307,324|328,328|330,332|335,335|337,338|343,345|349,364|369,376|378,378|381,381|386,407|409,409|411,422|426,436|438,438|444,451|454,476|479,480|483,502|512,513|515,521 E?TTSS??HHHHHHHHHHHHHTTHHHHHHHHHTT???BTTTTB???HHHHT?TT????EETTEESHHHHHHHHHHHHHHHHHHHHT?SB?TTS?B??EEEEE??GGGTHHHHHHHHHTGGG?TT----------S?EEEEE??SSHHHHHHHHTT??GGGEEEEEE?SSS??HHHHHHHHHHHHHHHHHH??-----GGGHHHHEEEESS?HHHHHHHT??GG--GEE???TTS?GGG?TTSGGG-HHHHHHH?HHHHHHHHHHHHHHHHHHHHS?GGG?HHHHHHHHHHHHHHTS???EEEEEES?STTTTHHHHHHHHHHHHH???B?TTS-?B?SS????EEE???TTTGGGTTHHHHHHSS????EEEEEEEE?S??H----HHHHHHHHHHHHHHHHHHHHHH?B?HHHHHHHHHHTT-??HHHHHHHGGGG?B?????EEEEEEEE??HHHHHHHHHHHHHHHHHHHHHHT??TT??GGGHHHHHHHHHHHHHHSSS????-----SS?HHHHHHH 3NBU|A PF00343.15_Phosphorylase_seed 9 744 !Q:6,7|16,17|22,22|41,42|49,50|53,53|55,55|68,69|75,76|79,79|82,82|86,86|93,93|97,99|101,101|104,104|106,108|113,113|127,127|132,132|143,145|151,151|154,154|157,157|175,178|181,185|216,216|220,221|254,256|272,276|281,281|292,292|316,316|318,318|326,326|330,336|340,340|352,352|354,354|378,378|385,388|390,390|399,399|411,412|418,418|431,431|458,458|460,462|473,475|500,502|504,507|514,517|520,520|540,540|555,556|567,567|573,575|579,579|581,582|593,593|598,598|600,600|611,611|618,618|620,621|632,635|643,643|662,662|673,678|683,683|686,686|740,743 Q:0,5|8,15|18,21|23,40|43,48|51,52|54,54|56,67|70,74|77,78|80,81|83,85|87,92|94,96|100,100|102,103|105,105|109,112|114,126|128,131|133,142|146,150|152,153|155,156|158,174|179,180|186,215|217,219|222,253|257,271|277,280|282,291|293,315|317,317|319,325|327,329|337,339|341,351|353,353|355,377|379,384|389,389|391,398|400,410|413,417|419,430|432,457|459,459|463,472|476,499|503,503|508,513|518,519|521,539|541,554|557,566|568,572|576,578|580,580|583,592|594,597|599,599|601,610|612,617|619,619|622,631|636,642|644,661|663,672|679,682|684,685|687,739 HHHHTT??HHHHHHHS??EEES?SHHHHHHHHHHHHHHHTT??EEEEEE??SB?S?EEEEETTEEEEE??BTTTT??TT?EE?GGG?EEEEES?EEE---E?SS?E---EEES?EEEEEEEEEEEEE?TTSS?EEEEEEEEEE?-?HHHHH?SS?TT?HHHHHHTHHHHHGGGSB????SS?????HHHHHHHHHHHHHHHHHHHHHHHHTTTSSS?TTT??GGGHHHHEEEEEESSTTTTHHHHHHHHHHHTS???HHHHHHHHHHHEEEE?????GGGS?EEEHHHHHHH?HHHHHHHHHHHHHHHHHHHHHST-T?HHHHHHH?SEE?------SSS?EEEHHHHHHHH?S?EEESSTTHHHHHHHTTTHHHHHH?GGGEEE????B?HHHHTTTT?HHHHHHHHHHH?-SGGGG?GGGGGGGGGGTT?HHHHHHHHHHHHHHHHHHHHHHHHHS?S???TTSEEEEEES???TTTTHHHHHHHHHHHHHHHHHSTT---S????EEEEEE????TT?HHHHHHHHHHHHHHHHHTT?TTTGGGEEEEEETT??HHHHHHHTTT?SEEEE???TTS?S??SHHHHHHHHT?EEEE?S?TTHHHHHHHH?GGGSEE?S??HHHHHHHHHH?-??HHHHHHH?HHHHHHHHHHHTTSSSTT?GGGGHHHHHH------HHHT?SS?TGGGHHHHHHHHHHHHHHHTSHHHHHHHHHHHHTTGGGGBHHHHHHHHHHHTT???? 1GPY|A PF00344.15_SecY_seed 157 597 !Q:0,1|4,5|20,35|38,38|40,40|46,46|48,50|86,101|103,106|108,108|110,110|113,114|120,121|140,140|142,144|146,146|159,159|166,197|200,202|204,206|210,230|239,247|249,256|267,267|273,277|279,289|292,312|314,318|321,321|323,323|331,332|338,340|347,351|354,391|394,403|406,406|409,446|453,453|470,470|475,475|488,488|492,493|497,497|501,501|512,512|518,518|528,529|535,536|538,561|566,566|568,570|575,578|583,586|591,593|597,597 Q:2,3|6,19|36,37|39,39|41,45|47,47|51,85|102,102|107,107|109,109|111,112|115,119|122,139|141,141|145,145|147,158|160,165|198,199|203,203|207,209|231,238|248,248|257,266|268,272|278,278|290,291|313,313|319,320|322,322|324,330|333,337|341,346|352,353|392,393|404,405|407,408|447,452|454,469|471,474|476,487|489,491|494,496|498,500|502,511|513,517|519,527|530,534|537,537|562,565|567,567|571,574|579,582|587,590|594,596 ??SS??SHHHHHHHHHHHHH----------------HH-H?SSSSS?S??-THHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGGSS???-------------S????S?S?ST--THHHH--HHHHHHHHHHHHHHHSTT-S??-S-SSHHHHHHHHHH-HHSSTT--------------------------------SS---S???SSS---------------------STTSSSHH---------H--------HHHHHHHHHH-HHHTT?????S???????????SS-------???????--???-?S?????SS?S?SSHHHHH--HHHHH---HHHHHS-----SS??-----------------------------------?SS--------??SS-SS???----------------------------------?SSGGGG-THHHHHHHHHHHHHHH-HHSS?TTHHHHHTTSTT?SSS??SSS-SSS?SHHHHHHHHH?HHHHH-HHHHHHHHH--HHTTS??S------------------------SSSS-S??-HHHH----HTHH----HHHH---HHH- 2YXQ|A PF00345.15_PapD_N_seed 154 190 !Q:0,3|5,5|13,14|16,16|18,18|26,26|28,28|31,31|33,33|41,46|49,57|59,60|63,64|67,67|70,72|74,79|84,84|91,91|101,101|103,103|105,116|119,121|123,124|135,170|181,185|188,189 Q:4,4|6,12|15,15|17,17|19,25|27,27|29,30|32,32|34,40|47,48|58,58|61,62|65,66|68,69|73,73|80,83|85,90|92,100|102,102|104,104|117,118|122,122|125,134|171,180|186,187 ????S?SEEEEET--T?S-EEEEEEE-E?SS-S?EEEEEEE------ES---------S??SS-?GG-GG??-S------EEEE-SSEEEE?TTEEEEEEE-E-E?--???----??SS---S-?EEEEEEEEEE????--------------???-----??---?????EEEEEEEEEE-?---TT?? 3DOS|A PF00346.14_Complex1_49kDa_seed 7 275 !Q:2,4|31,34|36,36|43,45|73,73|85,85|87,87|96,97|106,109|115,116|123,130|134,134|160,167|169,171|176,178|185,185|199,203|209,210|225,225|230,230|237,237|254,254|266,268|274,274 Q:0,1|5,30|35,35|37,42|46,72|74,84|86,86|88,95|98,105|110,114|117,122|131,133|135,159|168,168|172,175|179,184|186,198|204,208|211,224|226,229|231,236|238,253|255,265|269,273 HT???HHHHHHHHHHHHHHHHHHHHHSSSSS??-?B?SSBBSS???TTHHHHHHHHHHHHHHHHHHHHHHHHS?TTHHHHHSSSS?B?HHHHHHHT??SSSSGGGT????HHHHS??SSGGGS??????-?SSB?HHHHHHHHHHHHHHHHHHHHHHHHT?????--?B???TTTS???GGGGGT?HHHHHHHHHHHHS?????SEEEE??EEETTEEEEEEEEE?SSSS?SEEEEE?HHHHTTTTTTTTTSSS?SGGGTHHHHTT???HHHHH? 3I9V|4 PF00347.18_Ribosomal_L6_seed 132 93 !Q:1,1|4,5|7,9|13,16|22,22|26,30|34,36|39,41|46,50|58,60|62,62|66,67|80,83|87,87 Q:0,0|2,3|6,6|10,12|17,21|23,25|31,33|37,38|42,45|51,57|61,61|63,65|68,79|84,86|88,92 E?SS-?B???BTT----BEEEB?SSS??---EEE???TT-??EEEE-----ETTEEEE-??S?HHH--HHHHHHHHHTTS????SSS?EEEES 2ZJQ|E PF00348.12_polyprenyl_synt_seed 16 288 !Q:12,15|30,40|69,71|78,78|84,84|107,109|112,113|147,155|171,171|187,187|218,218|225,225|234,236|242,242|246,248|264,264|273,275|277,277 Q:0,11|16,29|41,68|72,77|79,83|85,106|110,111|114,146|156,170|172,186|188,217|219,224|226,233|237,241|243,245|249,263|265,272|276,276|278,287 HHHHHHHHHHSS?-??HHHHHHHHHHHHTT---------??HHHHHHHHHHHHHHHHHHHHHHTSTTTT???EETTEE?HHHHH?HHHHHHHHHHHHHHHHHHHHHS??-TT??HHHHHHHHHHHHHHHSTTTHHHHHHHHHHTTTT------???HHHHHHHHHHHTHHH-HHHHHHHHHHTTTHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHS?HHHHSS?TTHHHHHT???HHHHH?HHH---HHHHHHHHHHHHHHH-HHHHHTTT???H-HHHHHHHHHH 3PKO|A PF00349.16_Hexokinase_1_seed 14 237 !Q:0,2|15,16|37,38|45,45|47,51|53,54|57,61|63,64|66,69|80,81|90,98|106,115|124,126|146,153|156,157|165,165|167,167|170,170|175,176|179,182|185,192|212,212|214,215|223,223|236,236 Q:3,14|17,36|39,44|46,46|52,52|55,56|62,62|65,65|70,79|82,89|99,105|116,123|127,145|154,155|158,164|166,166|168,169|171,174|177,178|183,184|193,211|213,213|216,222|224,235 ???HHHHHHHTGGGS??HHHHHHHHHHHHHHHHHHHS--TTTGGG?S-----S??EE?????S??S????EEEEEEESSS--SEEEEEEE?????????EEEEEEE???-------HHHHTSBH---HHHHHHHHHHHHHHHHHHT?-------TT??EEEEEEE?S?EE?SSTT??EE????TT???-----BTTTTSBHHHHHHHHHHTT?S??EEEEEEE?HHHHHHHHHHTT? 3O5B|A PF00350.18_Dynamin_N_seed 79 332 !Q:5,5|21,40|43,43|47,87|90,93|95,102|105,111|118,118|122,123|125,126|138,216|227,227|234,250|252,259|282,282|284,284|289,292|296,298|308,308|311,311|314,322|324,324|330,330 Q:0,4|6,20|41,42|44,46|88,89|94,94|103,104|112,117|119,121|124,124|127,137|217,226|228,233|251,251|260,281|283,283|285,288|293,295|299,307|309,310|312,313|323,323|325,329|331,331 EEEEE?SSSSHHHHHHHHHTS??--??--????--??????EE-EEE-----------------------------------------EE????T--------TS?????--EEEESS-STT??B??THHHHHHHHHH??????-????????---------------------------------------------------------------?EEEEEEETTS?SEEEEE??????--?????????S--------HHHHHHHHHHHHHSTTEEEEEE-E-ESSS---?STT?--SHHHHHHHH?SS?SS---------E-EEEEE?T 3PR1|A PF00351.16_Biopterin_H_seed 6 332 !Q:0,3|14,14|16,24|32,32|49,50|54,61|84,84|99,100|105,107|120,121|126,126|129,131|147,152|155,155|158,159|162,163|194,195|213,213|224,225|231,231|244,245|248,249|256,259|263,264|266,267|272,272|288,289|306,306 Q:4,13|15,15|25,31|33,48|51,53|62,83|85,98|101,104|108,119|122,125|127,128|132,146|153,154|156,157|160,161|164,193|196,212|214,223|226,230|232,243|246,247|250,255|260,262|265,265|268,271|273,287|290,305|307,331 ????SBGGGGGGTT?S?????????TTSTTTT?HHHHHHHHHHHHHHHH??TTS????????HHHHHHHHHHHHHHHHHHHHHB?HHHHHHHHHHHHHS??BTTB???HHHHHHHHHHHT??EEEE?SS???HHHHHHHHTTTEEEE??????TT?TT??SS??HHHHHTTTTTTTTSHHHHHHHHHHHHHHTT??HHHHHHHHHHHHTTTTT?EEEETTEEEE??HHHHT?HHHHHHTTSSSS??EE??HHHHTT????SSS??S??EEES?HHHHHHHHHHHHHTS??SSEEEEETTTTEEEEE?HHHHHHHHHHHHHHHHHHHHHHHHH 2TOH|A PF00352.16_TBP_seed 135 107 !Q:1,4|15,15|18,21|26,26|31,33|37,39|42,42|45,45|54,57|60,61|64,66|72,72|74,74|84,84|86,86|94,94|106,106 Q:0,0|5,14|16,17|22,25|27,30|34,36|40,41|43,44|46,53|58,59|62,63|67,71|73,73|75,83|85,85|87,93|95,105 S??-?EEEEEEEEEE?SS-???HHHH-HHHS---TTE---EE?TT-TSSSEEEE----EE--TT---EEEEE-E?TTSEEEEES?S?HHHHHHH-HHHHHHHHHHH? 1NH2|A PF00353.14_HemolysinCabind_seed 305 18 !Q:1,2|5,6|10,11|14,15 Q:0,0|3,4|7,9|12,13|16,17 E??SS??EEE??SS??EE 3HB2|P PF00354.12_Pentaxin_seed 9 209 !Q:5,5|7,8|11,11|16,20|22,23|41,42|50,50|53,55|77,79|85,86|88,89|92,92|104,104|114,115|117,119|122,123|126,127|129,129|132,132|139,140|146,148|152,154|166,168|179,188|192,192|197,197|204,204 Q:0,4|6,6|9,10|12,15|21,21|24,40|43,49|51,52|56,76|80,84|87,87|90,91|93,103|105,113|116,116|120,121|124,125|128,128|130,131|133,138|141,145|149,151|155,165|169,178|189,191|193,196|198,203|205,208 EEEEE?S??SS?EEEE?????S?-BSEEEEEEEEEESGGGT??EEEEEEE?SS--?TTSEEEEEETTTEEEEEETTE---EEEEE??S??SS?EEEEEEEETTT?EEEEEETTE--E???EE??TT??B?SS?EEEESS??SBTTB???GGG???EEEEEEEEESS???HHHHHHHHHT-????----?SSB?GGGB?EEEESS?EEEE 2A3X|A PF00355.21_Rieske_seed 146 145 !Q:1,1|11,11|13,15|25,25|35,35|39,39|47,47|51,69|71,72|78,78|80,92|95,95|99,100|103,103|106,109|111,111|115,115|122,138|144,145 Q:0,0|2,10|12,12|16,24|26,34|36,38|40,46|48,50|70,70|73,77|79,79|93,94|96,98|101,102|104,105|110,110|112,114|116,121|139,143 S?EEEEEGGGS?S---TTEEEEEEE-TTEEEEEEE?TTS?EEEEESS?TTT???----------------S??SSEEE?S------?------EE?TTT??EE?TT----S?EEE?TTHHHH???-----?????????GGGSS?- 1SQB|E PF00356.16_LacI_seed 26 50 !Q:0,0|11,11|21,25|27,27|30,30|46,49 Q:1,10|12,20|26,26|28,29|31,45 ?HHHHHHHHTS?HHHHHHHHT??---S-SS?HHHHHHHHHHHHHHT???? 1QP7|A PF00357.15_Integrin_alpha_seed 27 15 !Q:0,1 Q:2,14 ??TTHHHHHHHHHHH 1S4W|A PF00358.15_PTS_EIIA_1_seed 14 133 !Q:2,2|4,5|7,7|30,30|40,40|44,44|54,54|68,68|74,74|78,78|89,91|94,94|97,97|100,100|106,106|117,118|126,127|130,131 Q:0,1|3,3|6,6|8,29|31,39|41,43|45,53|55,67|69,73|75,77|79,88|92,93|95,96|98,99|101,105|107,116|119,125|128,129|132,132 TS?B??B?SSSEEEEEGGGSSSHHHHTTSS?EEEEEEESS?EEE?SSSEEEEEE?TTSSEEEEEETTS?EEEEE?SBS?GGGTTTTEEE???TT?EE?TT?EEEEE?HHHHGGGSSB??EEEEESS??TT??E 1GGR|A PF00359.17_PTS_EIIA_2_seed 153 249 !Q:1,1|3,4|11,11|14,16|18,20|30,32|35,36|42,43|45,53|56,56|59,62|73,75|78,79|82,85|91,99|102,113|116,116|118,119|122,129|131,133|136,136|144,144|147,153|155,162|165,166|168,168|178,178|184,195|199,200|209,209|211,213|215,215|219,223|229,231|233,235|243,243|248,248 Q:0,0|2,2|5,10|12,13|17,17|21,29|33,34|37,41|44,44|54,55|57,58|63,72|76,77|80,81|86,90|100,101|114,115|117,117|120,121|130,130|134,135|137,143|145,146|154,154|163,164|167,167|169,177|179,183|196,198|201,208|210,210|214,214|216,218|224,228|232,232|236,242|244,247 H-H??GGGEEE-ES-??S---SHHHHHHHH---HH--HHHHT--T---------SB?TH----HHHHHHHHHH---HH??TT----EEETT---------EE?????-------GG-G--TB?-------S?--EE-EEEEEEE-EE-??----S-------?GG--G?SEEEEEEEE?SSHHH------------HHH--HHHHHHHH-H---T?HHH-----HHHHH---T-??SHHHHHH-HHTT? 3BJV|A PF00360.15_PHY_seed 80 215 !Q:6,8|27,29|39,39|56,58|73,78|80,86|89,89|92,92|97,97|100,100|119,119|124,126|132,135|143,143|147,147|161,167|173,173|175,180|186,190|205,205|208,212 Q:0,5|9,26|30,38|40,55|59,72|79,79|87,88|90,91|93,96|98,99|101,118|120,123|127,131|136,142|144,146|148,160|168,172|174,174|181,185|191,204|206,207|213,214 HHHHHH---HHHHHHHHSSSHHHHHHT--?HHHHHHTTT?SEEEEEETTEEEEEES???HHHHHHHHHHHHHS--?-??S------?EE-ES?GGGT-SG-GGGGGHHHHSEEEEEEET-TTEE---EEEEE????EEEEESS?GGG?SEEEEETTEEEEE???????EEEEE?S??????HHHHH-----HHHHHHHHHHHHHH-HH-----HH 3IBR|A PF00361.15_Oxidored_q1_seed 33 321 !Q:12,13|22,22|57,58|65,65|67,68|76,82|88,88|91,91|112,112|119,128|136,136|165,166|193,193|211,211|219,221|223,223|225,226|237,237|249,249|259,268|273,277|281,281|297,298|300,300|304,306 Q:0,11|14,21|23,56|59,64|66,66|69,75|83,87|89,90|92,111|113,118|129,135|137,164|167,192|194,210|212,218|222,222|224,224|227,236|238,248|250,258|269,272|278,280|282,296|299,299|301,303|307,320 BSBSHHHHHHHH--HHHHHHHH-HHTTSTTSHHHHHHHHHHHHHHHHHHHHHHHHHH--HHHHHT-S??BHHHHHH-------HHHHH?TT?SSSHHHHHHHHHHHHHHHHT?TTSTTH----------HHHHTTS?HHHHHHHHHTTHHHHHHHHHHHTHHHHH--TSHHHHHHHHHHHHHHHHHHHHHHTT?SBHHHHHHHHHHHHHHH-HHHHHHT---T?H--HHHHHHHHHH-HHHHHHHHHHH-HHHHHHTTS--------??BSTT??-??TTT?HHHHHHHHHHHHHHH--T?SSS---BHHHHHHHHHHHHH 4HEA|L PF00362.13_Integrin_beta_seed 48 712 !Q:8,8|10,12|14,66|69,70|73,75|78,81|86,91|95,103|106,117|120,120|123,161|164,164|166,169|172,172|175,175|184,221|228,229|231,233|242,242|266,266|269,269|280,282|289,291|295,295|298,299|301,305|308,314|325,325|336,341|347,347|358,386|392,395|397,397|409,409|411,412|418,419|423,424|426,429|431,432|437,446|449,450|455,462|481,518|526,534|537,548|556,556|558,559|567,567|587,587|593,596|599,599|608,608|611,611|613,613|620,621|626,629|632,632|634,651|663,672|675,679|686,690|693,699|707,711 Q:0,7|9,9|13,13|67,68|71,72|76,77|82,85|92,94|104,105|118,119|121,122|162,163|165,165|170,171|173,174|176,183|222,227|230,230|234,241|243,265|267,268|270,279|283,288|292,294|296,297|300,300|306,307|315,324|326,335|342,346|348,357|387,391|396,396|398,408|410,410|413,417|420,422|425,425|430,430|433,436|447,448|451,454|463,480|519,525|535,536|549,555|557,557|560,566|568,586|588,592|597,598|600,607|609,610|612,612|614,619|622,625|630,631|633,633|652,662|673,674|680,685|691,692|700,706 SHHHHSSS?S---S??????-?----------------------------------???????????SS??SS---SS----TTTT----??TTT?????--??EE?--?????????TT?SS??-----------------------------------??TT-T?-??EE?SS?EEEEBTTB-----------------------------------???EEEEEE??S???EEEEEEEE?SGGGHHHHHHGGGHHHHHHHHHH-TT?SSEEEEEEEE???SSTTTS???TTT-TT??S----?SS???????SEEEEEEEES?HHHHHHHHTT??????SSSSB?HHHHHHHHHH?----------------------------HHHHT??--S-SEEEEEEEESS?B??TTSGG--GGT??S????S??EETT----------EE??TTTS----????HHHHHHHHHHTTEEEEEE--------------------------------------EEGGGHH---------HH------------HHHHHHS-S--SEEEEEE?TTSTTHHHHHHHHHHHHHH?EEEEE????TT-EEEEEEEE?GG-G?EEETTG--GGEE????TT?E------------------EEEEEEEEESS-------???SS?---?EEEEEE-----TT????---EEEEEEE???-? 2P28|A PF00364.17_Biotin_lipoyl_seed 49 77 !Q:4,4|7,7|19,20|22,23|26,26|29,29|32,32|48,48|51,52|59,61|64,64|66,66|68,68|71,71 Q:0,3|5,6|8,18|21,21|24,25|27,28|30,31|33,47|49,50|53,58|62,63|65,65|67,67|69,70|72,76 EEEE?SS?EEEESSSSTTS??S??TT?EE?TT?EEEEEEETTEEEEEE?SS-?EEEEEE???TT?E-E?TT?EEEEE 2JKU|A PF00365.15_PFK_seed 12 313 !Q:0,0|6,7|10,11|30,30|34,35|45,45|47,47|50,51|53,54|61,61|64,65|67,67|70,75|94,96|103,103|130,130|140,141|149,149|152,154|157,157|159,160|181,182|185,186|193,194|197,198|210,210|213,215|219,222|225,225|241,241|243,244|247,247|252,254|258,261|274,276|281,283|288,288|290,292 Q:1,5|8,9|12,29|31,33|36,44|46,46|48,49|52,52|55,60|62,63|66,66|68,69|76,93|97,102|104,129|131,139|142,148|150,151|155,156|158,158|161,180|183,184|187,192|195,196|199,209|211,212|216,218|223,224|226,240|242,242|245,246|248,251|255,257|262,273|277,280|284,287|289,289|293,312 ?EEEEE??SS??TTHHHHHHHHHHHHHHTT?EEE??STHHHHHHS?G-GG??B??SGGGTT?TT??S?SS??????GGGSHHHHHHHHHHHHHH???EEEEEE?HHHHHHHHHHHHTTHHHHHHTTTTTS?TTTGGGSTT??EEEEEEB?TT???SS?S??BTHHHHHHHHHHHHHHHHTT??SS??EEEEEE??SS??HHHHHHHHHHT?SB???TTS?-??SS?HHHHHHHHHHHHHTT?S??BB?EETT???SSS????HHHHHHHHHHHT???EEEE???SSTT?S???HHHHHHHHHHHHHHHHHHHT 3U39|A PF00366.15_Ribosomal_S17_seed 15 71 !Q:0,0|5,6|15,19|21,21|25,26|28,32|38,39|42,46|49,49|56,58|63,64 Q:1,4|7,14|20,20|22,24|27,27|33,37|40,41|47,48|50,55|59,62|65,70 ?EEEE??SSSEEEEE?????B?TTT??B?????EEEEE??SS??-??SS?BEEEEE???SSSS??EEEEEE 3KIX|q PF00367.15_PTS_EIIB_seed 138 47 !Q:9,9|19,19|22,23|29,33|35,41|45,47 Q:0,8|10,18|20,21|24,28|34,34|42,44 HHHHHHHHT?STTEEEEEE?SS-?EEEEE-----S----?--GGG??- 3BP3|A PF00368.13_HMG-CoA_red_seed 116 533 !Q:12,14|21,60|67,68|71,72|76,111|134,134|142,149|156,158|177,178|191,192|196,196|198,201|228,232|235,235|238,238|241,243|246,246|249,255|268,268|272,273|289,292|296,298|301,305|311,312|314,314|316,317|320,321|328,329|340,340|347,347|350,352|355,355|362,362|377,377|379,380|400,401|410,410|422,434|436,436|448,450|459,459|471,472|474,475|489,493|510,515|519,532 Q:0,11|15,20|61,66|69,70|73,75|112,133|135,141|150,155|159,176|179,190|193,195|197,197|202,227|233,234|236,237|239,240|244,245|247,248|256,267|269,271|274,288|293,295|299,300|306,310|313,313|315,315|318,319|322,327|330,339|341,346|348,349|353,354|356,361|363,376|378,378|381,399|402,409|411,421|435,435|437,447|451,458|460,470|473,473|476,488|494,509|516,518 HHHHHHHHHHHH---HHSSST----------------------------------------TGGGGS??TT??GGG------------------------------------TBTTTBSSEEEEEEEEEEEEEE-EEETTEE--------EEEEEE???TTHHHHHHHHHHHHHHTT-?BEEEEEEEEEEE??EEE?S----SHHHHHHHHHHHHSHHHHHHHHHHHH-----TT?SS?EE???EE-EE-------ETTEEEEEEEEE?TTB??HHHHHHHHHHHHHHH----HHH?--TT----?EEEES??S?S??SS??HHHHHH??EEEEEEEEEE?HHHHHH-TS---SS?HHHHHH-HHHHHHTHHHHHTT?S--SEESSSHHHHHHHHHHHTT??GGGHHHHT?EEEEEEEESTT-------------S?EEEEEEEEEEE???SBSGGGGS-HHHHHHHHHTT??S??SSSTTHHHHHHHH-----HHHHHHHHHHHHHHHH------HHH???????????--? 2R4F|A PF00370.16_FGGY_N_seed 13 267 !Q:7,7|17,18|22,22|31,33|35,35|39,40|42,43|46,46|66,69|71,72|84,84|87,87|104,104|107,108|120,121|134,135|163,164|168,168|180,182|185,186|189,189|207,207|216,217|220,222|224,225|228,229|238,239|245,250|256,256 Q:0,6|8,16|19,21|23,30|34,34|36,38|41,41|44,45|47,65|70,70|73,83|85,86|88,103|105,106|109,119|122,133|136,162|165,167|169,179|183,184|187,188|190,206|208,215|218,219|223,223|226,227|230,237|240,244|251,255|257,266 EEEEEEE?SSEEEEEEE?-TTS?EEEEEEEE???B?SST--T??EE?HHHHHHHHHHHHHHHHHHH----T??GGGEEEEEEEE?SS?EEEEETTTTEEEEEEE?TT??TTHHHHHHHHH--TTTHHHHHHHTS??SSTTSHHHHHHHHHHHSTTHHHHHHHT??EEE?HHHHHHHHHTT---TS??EE?HHHHTTSSSEETTTTEE?HHHHHHHT??TT---S??EE??SEEEEEEE??SSSSS?----?EEEEE?EEHHHHHHHH 1BWF|O PF00372.14_Hemocyanin_M_seed 14 348 !Q:0,0|5,5|11,11|21,33|38,90|92,93|96,108|115,123|134,134|149,149|152,153|159,161|188,196|200,200|202,203|205,208|210,210|215,215|217,219|221,221|223,223|225,229|232,234|256,256|260,260|264,265|280,284|287,287|289,289|293,293|295,296|310,310|313,313|316,320|324,324 Q:1,4|6,10|12,20|34,37|91,91|94,95|109,114|124,133|135,148|150,151|154,158|162,187|197,199|201,201|204,204|209,209|211,214|216,216|220,220|222,222|224,224|230,231|235,255|257,259|261,263|266,279|285,286|288,288|290,292|294,294|297,309|311,312|314,315|321,323|325,347 ?HHHH?HHHHS?HHHHHHHHH-------------HHHH-----------------------------------------------------S??SS?------------EEEETT??????--?GGGGGHHHHT?HHHHHHHHHHHHHS?TT??HHHHS???TTHHHHHHHHHHHHHHHHHHHHHHHT?????????SSS?B??B????B?TTSS?B???B?S?B?????SS??-HHHHHHHHHHHHHHHHTTEEE?TTS?EEE??TTTHHHHHHHHHHT----?TT?S?HHH-H??HHHHHHHHHHTSS?SS?SS?????GGG?TTTGGGSTHHHHHHHHHHHHHHH 1HC1|A PF00373.13_FERM_M_seed 56 373 !Q:0,0|4,4|6,7|26,28|32,44|46,46|62,63|65,67|72,72|76,76|80,262|264,296|303,303|306,306|310,310|321,321|326,338|345,348|357,362|364,364|369,369 Q:1,3|5,5|8,25|29,31|45,45|47,61|64,64|68,71|73,75|77,79|263,263|297,302|304,305|307,309|311,320|322,325|339,344|349,356|363,363|365,368|370,372 ?HHH-H??SHHHHHHHHHHHHHHHHT---TSS----------???H-HHHHHHHHHHHHHHH?-S??-TTTS?TTT-TTT?-??-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S?--------------------------------HHHHTS?SS?HHH-HHHHHHHHHH-TTTT---------?--?HHHHHH----HHHHHHTT------S-TTTT?EEE 3BIN|A PF00374.14_NiFeSe_Hases_seed 12 585 !Q:0,1|10,10|22,22|43,46|78,79|86,87|99,99|102,102|104,106|111,112|127,128|134,135|138,140|143,146|181,184|189,189|191,193|195,196|207,207|212,212|246,250|256,256|260,265|271,273|275,275|277,277|284,285|289,289|292,292|295,296|298,304|307,307|315,315|321,322|324,324|328,328|330,330|334,337|339,343|346,346|351,355|361,362|366,368|371,371|379,380|382,382|395,398|403,403|422,427|436,442|483,486|488,489|492,492|498,498|532,532|539,542|545,548|557,557|559,559|561,561|565,565|576,577|584,584 Q:2,9|11,21|23,42|47,77|80,85|88,98|100,101|103,103|107,110|113,126|129,133|136,137|141,142|147,180|185,188|190,190|194,194|197,206|208,211|213,245|251,255|257,259|266,270|274,274|276,276|278,283|286,288|290,291|293,294|297,297|305,306|308,314|316,320|323,323|325,327|329,329|331,333|338,338|344,345|347,350|356,360|363,365|369,370|372,378|381,381|383,394|399,402|404,421|428,435|443,482|487,487|490,491|493,497|499,531|533,538|543,544|549,556|558,558|560,560|562,564|566,575|578,583 ??HHHHTTTS?GGGHHHHHHTT?SSSTTHHHHHHHHHHHHHHT????HHHHHHHHHHHHHHHHHHHHHHHHHTTGGGT??HHHHTT??HHHHHHHHHHH?TT?S???HHHH--HHHHHHHHHHHHTT??GGGTT??TT--?TT????HHHHHHHHHHHHHHHHHHHHHTHHHHHHHSSSSS?-??BTTB?S-??B??SGGGTTTSSB?HHHH-HHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHTT?????GGGGT?EEE----??EEESS---T-T?GGGEEE??EEE?TT?TT??B??----?TT?TTTEEEE?TTSSB??S?TTS?B?GGG????B?????TT?EEET-----TEEEE??TTS???SS?EEEETTB??B?SHHHHHHHHHHH----HHTT?GGGHHHHHHHHHHHHHHH------THHHHHHT???????HHHHSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT????B??TT?SGGGS?SEEEEEEEEEETTEEEEEEEEEETTEEEEEEEE?HHHHHT????TT????HHHHHHTT?B?S?TTS?HHHHHHHHHT??BHHHHH? 3RGW|L PF00375.13_SDF_seed 135 618 !Q:1,5|10,11|28,62|72,72|90,90|103,106|112,114|136,136|145,171|173,188|190,190|192,200|203,206|213,213|215,222|229,236|239,307|328,330|344,344|364,364|381,381|384,388|391,391|394,394|421,421|425,427|432,432|448,448|465,477|479,479|494,495|499,499|511,513|519,524|542,545|553,553|560,561|565,570|573,573|576,576|579,581|594,594|605,605 Q:0,0|6,9|12,27|63,71|73,89|91,102|107,111|115,135|137,144|172,172|189,189|191,191|201,202|207,212|214,214|223,228|237,238|308,327|331,343|345,363|365,380|382,383|389,390|392,393|395,420|422,424|428,431|433,447|449,464|478,478|480,493|496,498|500,510|514,518|525,541|546,552|554,559|562,564|571,572|574,575|577,578|582,593|595,604|606,617 S----?HHHH--HHHHHHHHHHHHHHTT--------------------------------?--HHHHHHHTH-HHHHHHHHHHHHHHHHH-HHHHHHHHHHSS?---HHHHH---HHHHHHHHHHHHHHHHHHHHH-HHHHHHHT??------------------------?S????----------??S?S?????????HH----HHHTTS?S?-------HHHHHH--------TT--------------------------------------------------------------------?HHHHHHHHHHHHHHHHHHHT--?SSHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHH-HG-----GG?ST-HHHHHHHHHHHHHHHHHHTHHHHHHH-HTT?-?HHHH-HHHHHHHHHHHHHHT?TTTSHHHHHHHHHHTT----------?--B?HHHHHHHHHHHHHH??HHH-HHHHHHHHHHH---HHHTT??-??-HHHHHHHHHHHHHTTTT????TTHHHHH-HHHHHH--HTT---???TT?HH-HH---HHHHHHHTHHHH-HHHHHHHHHH-HHHHHHHHHHHH 3V8G|A PF00376.18_MerR_seed 347 50 !Q:0,0|5,9|13,13|15,16|19,19|30,30|32,32|35,40|42,42|46,46|48,48 Q:1,4|10,12|14,14|17,18|20,29|31,31|33,34|41,41|43,45|47,47|49,49 ?HHHH-----HHH-H--TS?HHHHHHHHHH-T-SS?--???B?TTS?B?B 1Q07|A PF00377.13_Prion_seed 7 132 !Q:0,3|5,8|23,27|30,33|35,36|38,38|56,56|59,59|64,67|69,69|72,72|101,131 Q:4,4|9,22|28,29|34,34|37,37|39,55|57,58|60,63|68,68|70,71|73,100 ????S????SHHHHHHHHHHHTT?????EE????S-?S?HHHHHHHHHHHHHHHHT?TT?SSTT????S?SS?HHHHHHHHHHHHHHHHHHHHHHHHHHHH?------------------------------ 1E1W|A PF00378.15_ECH_seed 13 300 !Q:6,6|13,14|17,17|21,23|40,40|43,45|51,52|58,61|68,74|85,85|93,93|96,96|102,102|125,125|127,128|131,131|138,140|153,153|164,166|178,178|183,195|199,199|215,227|242,245|249,249|277,295 Q:0,5|7,12|15,16|18,20|24,39|41,42|46,50|53,57|62,67|75,84|86,92|94,95|97,101|103,124|126,126|129,130|132,137|141,152|154,163|167,177|179,182|196,198|200,214|228,241|246,248|250,276|296,299 EESGGG?EEEEEE??GG-GTT???HHHHHHHHHHHHHHHH?TT??-EEEEE??SSEEE????HHHHTT?-----?HHHHHHTTTT?GGGGGGG?SS?EEEEE?SEEETHHHHHHHTSSEEEEETT?E--EE?GGGGGT???SSSTTTHHHHHH?HHHHHHHHHH???EEHHHHHHHTS?SEEE?------------TTT-HHHHHHHHHHHHHHS------------?HHHHHHHHHHHHGG----GTS?HHHHHHHHHHHHHHHTTSHHHHHHHHH-------------------HHTT 4JJT|A PF00380.14_Ribosomal_S9_seed 183 337 !Q:0,2|5,8|12,12|15,15|17,46|51,51|54,65|68,70|75,76|91,91|94,154|158,189|194,213|216,216|235,271|273,277|280,292|300,305|307,307|310,319|321,322|329,333|335,336 Q:3,4|9,11|13,14|16,16|47,50|52,53|66,67|71,74|77,90|92,93|155,157|190,193|214,215|217,234|272,272|278,279|293,299|306,306|308,309|320,320|323,328|334,334 ???SS????EEE-ES-S---------------------?----?-?-EEES-SS------------BI---IIII--SSSSSTTSTTHHHH-TT??-----------------------------------------------------------SSS-------------------------------?EEEE?-----------------??SS?HHHHHHHHHHHHHHHHHH-------------------------------------H?----TT------------?HHHHHHH------T?SS??????????T--TSSSTT?????S?? 3KIX|i PF00381.14_PTS-HPr_seed 168 112 !Q:0,2|5,5|9,11|13,14|20,20|27,28|37,38|46,46|49,49|51,54|61,61|70,71|74,74|84,92|107,109 Q:3,4|6,8|12,12|15,19|21,26|29,36|39,45|47,48|50,50|55,60|62,69|72,73|75,83|93,106|110,111 ?--EE-EEE---E??STTSS?HHHHHH--HHHHHTTS--SSEEEEE-ET-T----EEEETT?HHHHHHHT??TT?EEEEEEEST---------THHHHHHHHHHHHH---TT 1GGR|B PF00382.14_TFIIB_seed 12 74 !Q:9,10|12,14|32,33|37,37|55,58|69,69 Q:0,8|11,11|15,31|34,36|38,54|59,68|70,73 HHHHHHHHT??H---HHHHHHHHHHHHHHHTT??TTS?HHHHHHHHHHHHHHHHT????HHHHHHHSSS?HHHH 3K7A|M PF00383.17_dCMP_cyt_deam_1_seed 59 207 !Q:0,2|17,22|26,27|34,35|45,45|47,48|52,53|63,63|67,88|92,92|107,107|109,109|122,124|126,151|154,156|161,173|176,178|180,180|182,187|196,196|198,200 Q:3,16|23,25|28,33|36,44|46,46|49,51|54,62|64,66|89,91|93,106|108,108|110,121|125,125|152,153|157,160|174,175|179,179|181,181|188,195|197,197|201,206 ??-HHHHHHHHHHHHTT?---??SSB??EEEEEE--TTEEEEEEE?B??TTS??HHHHHHHHT?EEE??????????????????????EEE?GGGHHHHHHHHHHH?B?HHHHHHHHHHHH---T???-----------------------TT--?EEEE-------------EE???H-H------HHHHHHHH-T-??EEEEEE 3ZPC|A PF00384.17_Molybdopterin_seed 32 833 !Q:1,2|4,4|21,21|34,34|49,49|53,54|74,74|81,83|85,87|107,107|111,112|118,118|120,120|129,129|131,135|138,162|167,167|170,171|177,178|187,198|210,210|216,216|219,220|223,223|227,229|235,239|242,242|261,262|265,266|288,288|298,298|309,310|316,316|318,318|325,325|328,328|340,340|342,343|345,345|353,354|356,357|359,362|366,366|376,377|380,382|386,391|409,409|427,428|431,432|442,443|446,446|455,457|478,478|484,484|486,487|493,497|516,516|522,522|527,527|530,533|549,549|551,552|556,556|571,574|580,580|584,584|589,589|591,591|606,607|610,610|614,614|628,628|640,669|673,673|678,678|686,687|694,695|701,701|713,713|715,719|721,722|728,731|735,737|740,757|767,769|775,775|782,783|787,790|792,792|796,797|805,807|810,811|814,815|819,819|821,821 Q:0,0|3,3|5,20|22,33|35,48|50,52|55,73|75,80|84,84|88,106|108,110|113,117|119,119|121,128|130,130|136,137|163,166|168,169|172,176|179,186|199,209|211,215|217,218|221,222|224,226|230,234|240,241|243,260|263,264|267,287|289,297|299,308|311,315|317,317|319,324|326,327|329,339|341,341|344,344|346,352|355,355|358,358|363,365|367,375|378,379|383,385|392,408|410,426|429,430|433,441|444,445|447,454|458,477|479,483|485,485|488,492|498,515|517,521|523,526|528,529|534,548|550,550|553,555|557,570|575,579|581,583|585,588|590,590|592,605|608,609|611,613|615,627|629,639|670,672|674,677|679,685|688,693|696,700|702,712|714,714|720,720|723,727|732,734|738,739|758,766|770,774|776,781|784,786|791,791|793,795|798,804|808,809|812,813|816,818|820,820|822,832 B??S?EEEHHHHHHHHHHHTT?SSHHHHHHHHHT?HHHHHHHHTTTTSS?EEE??HHHHHHHHHHHHHHHHHHT?GGGEEE---E???GGGSHHHHHHHHHHHHHHT?EEE??TTTTT?S?THHHHHHS?S?????HH-------------------------HHTT?SE--EEEES??HHHHSGGG------------HHHHHHHGGGT?EEEEE?SS??HH-HHT---SSEEE??--?TT?HHHHHHHHHHHHHHHHTT--TS??HHHHHHHHHHBSTTBEEEEEE?SSSEEEEEE?BGGGBTTGGG??SSGGG?B?EEBTTS?EE?BTTSGGGTSSS?S??S?SSBBTTT??B??B????TTS?SEEEEEEEE??TT???TTS??????SEEEEEEEEEEEEBTTS?EEEEEEHHHHHHHHTTB??SS??TTSBSSTTS??TT?HHHHHHHH???HHHHHHHHHHHHHHHHHHTS?EEEEE?H--HHHTS-----TTHHHHHHHHHHHHHHTT?TTSTT?EEEE?SS????SSHHHHHHHHHTTTT?S??EEE?HHHHHHHHTTGGGG????SGGGS?TTS?GGGS?S?HHHHHHHHHHTTSS??SS?BSS?TTSHHHHHHHTTS?HHHHHHHHHHH------------------------------TSS?BGGG?TTSSSSS??EEEEES??TTTTT?SSHHHHHHHTT?S?????S??TTTTT????SSS???SS???----?----??----SEEEEEESB?-?HHHHT?SEEEEB??TTS----S?EEE??SSSSEEE---EE??SS??STT?B?HHHHHHHHHHH 2IV2|X PF00385.19_Chromo_seed 173 87 !Q:0,4|7,8|12,13|15,15|19,19|21,37|42,42|46,46|48,48|50,52|55,56|61,62|65,65|67,67|70,74|78,79 Q:5,6|9,11|14,14|16,18|20,20|38,41|43,45|47,47|49,49|53,54|57,60|63,64|66,66|68,69|75,77|80,86 ?????EE--EEE--E?TTS?E-----------------EEEE?BTT-B?G---GG?-EEEE--TT-T?TT?----HHH--HHHHHHH 3I8Z|A PF00386.16_C1q_seed 46 151 !Q:5,6|10,14|16,28|30,33|37,37|40,41|51,51|54,54|65,67|72,72|77,78|83,85|95,103|116,116|119,119|126,136|139,140|143,143 Q:0,4|7,9|15,15|29,29|34,36|38,39|42,50|52,53|55,64|68,71|73,76|79,82|86,94|104,115|117,118|120,125|137,138|141,142|144,150 EEEEE??SSB???-?S--------?????E----EEE?TT??EETTTTEEE?SS?EEEEEEEEEE---EESS?EEEE--EEET---TEEEEEEEE??????---EEEEEEEEEEEE?TT?EEEEEE???????????BS?-TT?EEEEEEE 2OII|A PF00387.14_PI-PLC-Y_seed 86 157 !Q:5,5|8,8|11,19|23,23|29,31|49,49|52,53|57,58|67,67|72,73|75,77|79,79|81,81|83,88|97,97|100,113|115,115|117,117|120,121|124,124|137,143|146,146|151,152 Q:0,4|6,7|9,10|20,22|24,28|32,48|50,51|54,56|59,66|68,71|74,74|78,78|80,80|82,82|89,96|98,99|114,114|116,116|118,119|122,123|125,136|144,145|147,150|153,156 HHHTT?SS?EE??----???HHH-HHHHT--?TTEEEEEEHHHHHHHHH-HS--HHH--HHHHHHHS?EEEE??T---T?T-T????-?THHHHTTT?SE--------------E?B?TT??SH-HHHHHHHHHTTG-------GG?SEEE??GGGT 1DJZ|A PF00388.14_PI-PLC-X_seed 140 344 !Q:3,3|10,10|20,49|53,60|62,62|74,75|83,91|95,215|218,222|226,234|252,253|255,265|267,267|276,278|283,284|300,301|303,304|307,324|327,329|336,336|342,343 Q:0,2|4,9|11,19|50,52|61,61|63,73|76,82|92,94|216,217|223,225|235,251|254,254|266,266|268,275|279,282|285,299|302,302|305,306|325,326|330,335|337,341 TTS?GGGEEE?EESSTTBSS-----------------------------?TTT-----??-B?HHHHHHHHHTT??EEEEEEE-------??GGG---?------------------------------------------------------------------------------------------------------------?--------EE??---TTS??---??--EEHHHHHHHHHHHTTTS?-S-----------S?EEEEEEEE?-?HHHH--HHHHHHHHHHHGGGB??S??SS----------------??SS???TTTTTT?EEEEE?? 1DJZ|A PF00389.25_2-Hacid_dh_seed 98 363 !Q:3,3|5,8|10,13|21,21|23,31|38,41|44,44|47,48|57,59|65,65|69,74|76,76|81,81|84,86|89,90|98,99|103,103|112,112|116,117|120,120|152,154|158,159|161,163|166,166|172,173|189,189|195,195|199,199|208,208|211,212|218,236|239,239|245,249|255,255|257,257|265,265|273,273|280,280|300,301|306,309|314,314|320,320|323,323|326,328|351,357|361,361 Q:0,2|4,4|9,9|14,20|22,22|32,37|42,43|45,46|49,56|60,64|66,68|75,75|77,80|82,83|87,88|91,97|100,102|104,111|113,115|118,119|121,151|155,157|160,160|164,165|167,171|174,188|190,194|196,198|200,207|209,210|213,217|237,238|240,244|250,254|256,256|258,264|266,272|274,279|281,299|302,305|310,313|315,319|321,322|324,325|329,350|358,360|362,362 EEE?S----S?--?SGGGTTS?T---------TSEEEE--??TT?HH--HHHHHGGG--?SEEEE?SSS-----?B?HHHH-HH?--TT??EEEESSS??TTB?HHHHHHTT?EEE??TT-SSHHHHHHHHHHHHHHHHTTHHHHHHHHHHT???GGG??B???TT?EEEEE??SHHHHHHHHHHHHTT?EEEEE?TTS?HHHHHHTT?EE??HHHHH-------------------HH?SEEEE?????TTTTT?B?HHHHTTS?TTEEEEE?SSTTSB?HHHHHHHHHHTSEEEEEES??SSSS????GGGG?SSEEE?SS?TT?--BHHHHHHHHHHHHHHHHHHHTT----???TTB?S 4E5M|A PF00390.14_malic_seed 48 189 !Q:3,3|15,15|39,39|42,44|55,57|67,69|71,73|79,79|83,83|87,89|91,91|110,112|124,127|133,133|136,137|139,139|142,145|165,165|168,168|173,173|175,176 Q:0,2|4,14|16,38|40,41|45,54|58,66|70,70|74,78|80,82|84,86|90,90|92,109|113,123|128,132|134,135|138,138|140,141|146,164|166,167|169,172|174,174|177,188 HHH?HHHHHHHHHHT-HHHHHHHHSTTHHHHHHHTHHHH?SS??-SEEEEGGGTT--?HHHHHHTSS--?S???EEEEE?SSS?GGG???G-GGGGHHHHHHHHHHHHTT???GGGEEEEEEES????HHHHH?TT??S?SS????THHHHHHHHHHHHHHHHHH?TT?EEEE?S??HHHHHHHHHHHT 1LLQ|A PF00391.18_PEP-utilizers_seed 179 118 !Q:0,15|21,24|30,32|37,37|45,47|50,53|61,66|70,72|74,74|76,88|93,98|100,100|102,103|105,106|109,117 Q:16,20|25,29|33,36|38,44|48,49|54,60|67,69|73,73|75,75|89,92|99,99|101,101|104,104|107,108 ???????--????--?EEEES?-??GGGSH---HHHT?SEEEESS?-?TT---?HHHHHTT?????-EEE??-T-T-------------HHHH------S?S--S??EE????????? 1VBG|A PF00392.16_GntR_seed 26 64 !Q:18,18|21,21|23,25|35,36 Q:0,17|19,20|22,22|26,34|37,63 HHHHHHHHHHHHHHTTSS?TT?B???HHHHHHHHT??HHHHHHHHHHHHHTTSEEEETTTEEEE 3C7J|A PF00393.14_6PGD_seed 58 328 !Q:30,32|45,45|50,50|63,63|65,69|73,73|75,76|78,83|90,96|111,113|128,128|138,138|141,156|158,158|194,197|212,212|216,216|227,227|230,230|232,232|256,256|263,265|280,280|283,283|285,285|298,300|302,302|305,314|317,317|319,321|323,327 Q:0,29|33,44|46,49|51,62|64,64|70,72|74,74|77,77|84,89|97,110|114,127|129,137|139,140|157,157|159,193|198,211|213,215|217,226|228,229|231,231|233,255|257,262|266,279|281,282|284,284|286,297|301,301|303,304|315,316|318,318|322,322 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHT???HHHHHHHHHHHT-TTTT?BHHHHHHHHHTT?B?----TTT-S--S------BGGGTB???????TTTTHHHHHHHHHT???HHHHHHHHHHHHHH?HHHHHHHHT-TS??---??----?????S?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT????HHHHHHHTTSSSTT?BTT-HHHHHHHHHH?TT?S?GGGSHHHHHHHHHHHHHHHHHHH-HHHHHT???HHHHHHHHHHHHHT?SS?T-HHHHHHHHHHHH???B?BS----------SS?S?--B????? 1PGQ|A PF00394.17_Cu-oxidase_seed 72 218 !Q:10,11|14,14|18,28|30,30|33,38|41,41|50,51|55,57|59,88|91,93|98,98|101,101|109,109|111,112|115,116|124,126|133,138|145,146|156,156|159,159|167,171|173,177|189,193|197,197|199,203 Q:0,9|12,13|15,17|29,29|31,32|39,40|42,49|52,54|58,58|89,90|94,97|99,100|102,108|110,110|113,114|117,123|127,132|139,144|147,155|157,158|160,166|172,172|178,188|194,196|198,198|204,217 GGGEEEEEEE?-SS?TTT-----------S?SS-----?SS?SEEEETTB??BTT?--T------------------------------TS???EEEE?TT?EEEEEEE-E??SS??EEEEETT?-?EEEEEE------TTEEEE--EEEESBEEE?TT?EEEEEEE?---?S-?---SSEEEEEEEES-----SSS?S----?GGGTTEEEEEETTS 3T71|A PF00395.15_SLH_seed 175 64 !Q:0,0|5,5|12,15|26,26|28,31|33,35|38,52|55,55|57,57 Q:1,4|6,11|16,25|27,27|32,32|36,37|53,54|56,56|58,63 ?BTTB?TTSTTH----HHHHHHHHTT-S????T---TS--------?----??TT?B?BHHHHH 3PYW|A PF00396.13_Granulin_seed 94 52 !Q:0,0|4,4|7,7|10,13|17,18|30,30|33,33|36,41|50,50 Q:1,3|5,6|8,9|14,16|19,29|31,32|34,35|42,49|51,51 ?EEE?SS-SS----EEE??SSSSTTSSSSS?SS?SS?----?EETTTTEE?S 2JYT|A PF00397.21_WW_seed 547 41 !Q:0,1|4,4|6,6|8,8|12,14|17,21|23,23|26,26|38,40 Q:2,3|5,5|7,7|9,11|15,16|22,22|24,25|27,37 ??TT-E-E-EEE?--SS-----S?EE-EEETTTTEEES??? 1O6W|A PF00398.15_RrnaAD_seed 20 342 !Q:1,1|4,5|9,11|13,14|26,26|31,33|37,37|44,44|47,47|58,60|67,69|82,85|89,89|92,92|94,94|96,96|99,99|111,111|114,123|137,139|158,158|182,183|189,190|209,209|212,212|216,218|221,221|229,234|237,238|241,244|247,247|250,253|255,257|266,269|271,276|294,294|308,308|314,316|318,321|327,327|331,332 Q:0,0|2,3|6,8|12,12|15,25|27,30|34,36|38,43|45,46|48,57|61,66|70,81|86,88|90,91|93,93|95,95|97,98|100,110|112,113|124,136|140,157|159,181|184,188|191,208|210,211|213,215|219,220|222,228|235,236|239,240|245,246|248,249|254,254|258,265|270,270|277,293|295,307|309,313|317,317|322,326|328,330|333,341 T?SS??GGG???B??HHHHHHHHHHH?GGGT???TTT?EEEEES?TT?HHHHHHHHHH?-?SEEEEE???HHHHHHHHHHTT----TSS?EE-E?S?TT?HHHHHHHTTTT?SS????----??TTSEEEEEEEEEE??-STTHHHHHHHHHHHHHHT?GGGGGSEEEEEEEEEHHHHHHHH??TTSTT??HHHHHHHHHEEEEEEEES?GG-GGG---GS?HHHHHHH----??EE??GG----GB-SS?---S???EEEEEEEE????S-----?HHHHHHHHHHHHTTTTS?TTTGGGGSSTTHH-HHHTT---T????TTTSS?GGG??HHHHHHHHH 3FTF|A PF00400.27_WD40_seed 1804 66 !Q:0,1|7,10|13,13|20,21|23,23|31,36|38,48|55,56 Q:2,6|11,12|14,19|22,22|24,30|37,37|49,54|57,65 ??EEEEE-???SS?EEEEEE??S?GGGGGGG??----S???????????EEEEEE--TTSEEEEEE 2O9K|A PF00401.15_ATP-synt_DE_seed 179 55 !Q:2,3|20,23|26,33|54,54 Q:0,1|4,19|24,25|34,53 GG??HHHHHHHHHHHHHHHT??--SS-??----?HHHHHHHHHHHHHHHHHHTT? 3OAA|H PF00403.21_HMA_seed 73 92 !Q:6,6|8,8|23,23|27,29|39,39|47,51|55,56|59,65|68,69|76,83|85,87|90,90 Q:0,5|7,7|9,22|24,26|30,38|40,46|52,54|57,58|66,67|70,75|84,84|88,89|91,91 EEEEES?S?TTHHHHHHHHHTTS-SSE---EEEEEEGGG-TEEEEEE----?TTT-?SS-------HH--HHHHHH--------H---HT?E 3IWL|A PF00404.13_Dockerin_1_seed 130 21 !Q:0,0|3,3|6,7 Q:1,2|4,5|8,20 ?TT?SS??SHHHHHHHHHHHH 4DH2|B PF00405.12_Transferrin_seed 10 349 !Q:0,1|4,4|25,32|35,36|51,52|57,57|70,70|99,102|105,106|115,115|118,118|128,129|137,140|144,144|158,158|162,162|164,164|167,167|174,177|182,183|185,185|193,193|207,207|221,222|228,235|252,252|257,257|263,264|273,274|294,294|297,298|301,303|306,310|312,312|316,316|319,320|325,326|329,330|336,336 Q:2,3|5,24|33,34|37,50|53,56|58,69|71,98|103,104|107,114|116,117|119,127|130,136|141,143|145,157|159,161|163,163|165,166|168,173|178,181|184,184|186,192|194,206|208,220|223,227|236,251|253,256|258,262|265,272|275,293|295,296|299,300|304,305|311,311|313,315|317,318|321,324|327,328|331,335|337,348 ??EE?SSHHHHHHHHHHHHHHHHTT---?????EE??SSHHHHHHHHHTTS??BEEE?HHHHHHHHSTTT?EEEEEEEEEEETTEEESEEEEEEEEETT????TT??TTSEEEES?TT?TTTTHHHHH--HHGGGTT???-TTS?HHHHHHHHSSEEE?TTS?T-TT?HHHHTT????STTT--T?SSTTSTT?HHHHHHHHHHTTS?SEEEEETTHHHHH??STTTG--------GGEEEEETTTEEEETT?GGGS?SEEEE??EEEEESSS??HHHHHHHHHHHHHHHSTTS?SS??TT???TT?----S?SSS?TT??EEEE??TT??HHHHH?HHHHHHHHGGGS 4G77|A PF00406.17_ADK_seed 23 191 !Q:2,2|20,22|35,35|39,39|53,56|72,73|78,78|84,86|103,105|113,114|132,133|141,143|149,149|153,154|158,159|162,162|190,190 Q:0,1|3,19|23,34|36,38|40,52|57,71|74,77|79,83|87,102|106,112|115,131|134,140|144,148|150,152|155,157|160,161|163,189 EE?STTSSHHHHHHHHHHHH???EEEHHHHHHHHH-HHT?HHHHHHHHHHHHT????HHHHHHHHHHHHTSG--GGTT?EEEES???SHHHHHHHHHHHHHHT???SEEEEEE??HHHHHHHHHTEEEETTT??EEETTTB??-SSTTB?TTT??BEE??TT?SHHHHHHHHHHHHHHHHHHHHHHHHHT? 2BBW|A PF00407.14_Bet_v_1_seed 34 162 !Q:14,14|25,26|29,32|34,34|37,39|42,45|47,48|50,50|53,54|56,58|65,65|91,92|110,110|134,135|143,146|161,161 Q:0,13|15,24|27,28|33,33|35,36|40,41|46,46|49,49|51,52|55,55|59,64|66,90|93,109|111,133|136,142|147,160 SSEEEEEEEEEESS?HHHHHGGGSS-?SS????S?SS-??SS????S??S?ST--T???EEEEEE-TTEEEEEEEEEEEEETTTTEEEEEE??TTGGGTEEEEEEEEEEE-EEEETTEEEEEEEEEEEESSTTT??THHHHHH----HHHHHHHHHHHHHS? 3NJ1|A PF00408.15_PGM_PMM_IV_seed 112 139 !Q:0,0|5,6|8,9|11,20|33,60|63,64|68,68|76,76|79,85|93,93|99,101|110,110|126,136 Q:1,4|7,7|10,10|21,32|61,62|65,67|69,75|77,78|86,92|94,98|102,109|111,125|137,138 ?EEEE??T--T----------THHHHHHHHHHH??-------------------------?SS?-EEE?SSSEEEE?SS-------EEEEEEE?SSSSE---EEEEEEES-SHHHHHHHHHHHHHH-----------HH 1JDY|A PF00410.14_Ribosomal_S8_seed 119 228 !Q:0,0|17,17|23,23|25,50|72,75|86,91|100,101|119,120|126,126|128,128|132,137|141,141|144,145|147,147|149,149|153,153|155,155|159,160|163,163|167,176|179,180|186,196|205,205|217,219|227,227 Q:1,16|18,22|24,24|51,71|76,85|92,99|102,118|121,125|127,127|129,131|138,140|142,143|146,146|148,148|150,152|154,154|156,158|161,162|164,166|177,178|181,185|197,204|206,216|220,226 ?HHHHHHHHHHHHHHTT?SEEEE-E?------------------------?HHHHHHHHHHHHHTSEEEEEE--??HHHHHHHHHH------HHHHHHSS??SSSHHHHHHHHHTTSTT??EEEEE-E?BSS------TTS?SB--S?S?EEE?S?SSS??EE?STT???-------SG--GGTSE-----------EEEEETTE-EEEHHHHHHTT?-?EEEEEEE? 3KIX|h PF00411.14_Ribosomal_S11_seed 13 124 !Q:0,0|7,7|9,12|14,14|21,21|25,25|37,38|42,43|64,66|75,83|99,99|107,112|114,123 Q:1,6|8,8|13,13|15,20|22,24|26,36|39,41|44,63|67,74|84,98|100,106|113,113 ?EEEEEE?S----S?EEEEEE?SSS?EEEEEETTTSS??TTS-?SSHHHHHHHHTSGGGTSTTT???EEEEEEES--------?STTSSHHHHHHHTTT?EEEEEEE??????S-????????? 3KIX|k PF00412.17_LIM_seed 38 73 !Q:0,0|4,4|7,12|26,26|30,30|32,32|36,37|44,46|54,55|57,60|63,63|66,66 Q:1,3|5,6|13,25|27,29|31,31|33,35|38,43|47,53|56,56|61,62|64,65|67,72 ?TTT?SB??----SSEEEEETTTEEE?GGG?B?TTT??BGGGSS---EEEEETT--E----EE?HH-HHHHHT 3MMK|A PF00413.19_Peptidase_M10_seed 66 398 !Q:0,2|5,5|8,11|17,22|26,26|42,42|46,51|54,55|60,68|70,72|74,78|86,98|101,101|105,110|115,123|125,125|129,130|134,141|146,146|154,157|164,166|168,168|178,179|192,192|194,194|197,197|200,202|214,215|219,221|225,227|234,237|250,250|252,252|255,255|258,260|267,267|272,273|277,282|284,284|292,295|308,308|310,310|313,313|317,318|325,325|330,331|335,339|356,359|361,361|367,367|370,374|377,385|397,397 Q:3,4|6,7|12,16|23,25|27,41|43,45|52,53|56,59|69,69|73,73|79,85|99,100|102,104|111,114|124,124|126,128|131,133|142,145|147,153|158,163|167,167|169,177|180,191|193,193|195,196|198,199|203,213|216,218|222,224|228,233|238,249|251,251|253,254|256,257|261,266|268,271|274,276|283,283|285,291|296,307|309,309|311,312|314,316|319,324|326,329|332,334|340,355|360,360|362,366|368,369|375,376|386,396 ??-SS-SE----EEEEE????--TTS?HHHHHHHHHHHHHHH-HTS------SS-?EEEE??-------S---S?---?SEEEEEE------------?SS?SSS??--??SSSS---------B?EEE??SSS--------TTTT?EEEETTS---?EESSSS???B?BSGGGTTSB??SSEEETTEEESS?B?TT?SS???EEESSSBTTTS??EEE???TTT???STTTTT????SSEEETTEEESS?B?TT?SS???EEESSS?TTTS??EEE??????S?BSTTTTT????SSEEETTEEESS?B?TT?SSS??EEESSS?HHHH??EEE?????EEHHHHHHHHHHHHTT????S?TTSTT?SB??-??SS-----????HHHHHHHHHHH? 1HV5|A PF00415.13_RCC1_seed 104 81 !Q:2,2|8,11|17,31|37,37|44,45|47,48|52,65|71,71|73,73 Q:0,1|3,7|12,16|32,36|38,43|46,46|49,51|66,70|72,72|74,80 TS?EEEEE--??TTSTT?--------------SSSSS?EEEEEE--E??GGG------------??EEEEE-E?SSEEEEE 4D9S|A PF00416.17_Ribosomal_S13_seed 15 131 !Q:7,7|12,13|24,25|38,39|48,48|67,68|77,77|81,83|85,87|107,107|116,116|118,118|121,124|127,127|129,130 Q:0,6|8,11|14,23|26,37|40,47|49,66|69,76|78,80|84,84|88,106|108,115|117,117|119,120|125,126|128,128 EETTEEE?TTSB--HHHHGGGSTT??STTHHHHHHHTT??TTSBSSSS?HHHHHHHHHHHHSGGGGT??GGGSSBSS?SSS???B???HHHHHHHHHHHHHHHHHHT?HHHHHHHS?S?SS????SS?S?? 3KIX|m PF00419.15_Fimbrial_seed 244 329 !Q:0,3|5,5|7,16|19,27|32,33|37,50|55,55|60,61|63,64|66,66|70,76|80,80|82,82|91,98|101,101|104,117|119,119|125,125|129,143|150,150|155,161|163,163|168,168|170,181|188,225|230,231|233,233|235,257|261,271|274,275|279,281|286,291|299,300|304,313|315,317|327,327 Q:4,4|6,6|17,18|28,31|34,36|51,54|56,59|62,62|65,65|67,69|77,79|81,81|83,90|99,100|102,103|118,118|120,124|126,128|144,149|151,154|162,162|164,167|169,169|182,187|226,229|232,232|234,234|258,260|272,273|276,278|282,285|292,298|301,303|314,314|318,326|328,328 ????S-S?------???SS??----?--HHHH--EEE--------------EEEE-EEEG--G--G?SSE-------EEE?S?EEEEEEEE--------EE?TT--------------T?SEEEE-EEE--------??-----BSSGGG-TTSB??----?S?TTTS?S------------SEEEEE--------------------------------------EETT--S?B----?-----------------?BTS??-----????EE??SEE---EEEE------EEEEEEE--ESS???-------S???EEEEEEEEE-E 3RFZ|A PF00420.19_Oxidored_q2_seed 194 139 !Q:19,21|49,91|93,93|125,125|128,128|133,138 Q:0,18|22,48|92,92|94,124|126,127|129,132 HHHHHHHHHHHHHHHHHHH-??BHHHHHHHHHHHHHHHHHHHHHHHHHT-------------------------------------------T?SHHHHHHHHHHHHHHHHHHHHHHHHHHTTTT?SS?BGGG?????? 4HEA|K PF00421.14_PSII_seed 19 525 !Q:0,1|14,14|44,45|48,48|53,53|59,59|70,71|73,73|77,77|81,82|85,88|90,98|123,125|128,131|136,136|140,140|143,145|175,176|180,184|190,190|194,199|208,208|212,221|244,245|255,255|257,257|283,283|288,288|293,295|320,321|330,330|342,342|346,346|350,351|353,353|359,359|365,366|372,372|375,376|381,384|387,387|390,392|396,396|399,400|405,406|412,412|414,414|421,421|433,433|436,436|453,453|458,458|463,464|466,470|505,505|507,511|513,524 Q:2,13|15,43|46,47|49,52|54,58|60,69|72,72|74,76|78,80|83,84|89,89|99,122|126,127|132,135|137,139|141,142|146,174|177,179|185,189|191,193|200,207|209,211|222,243|246,254|256,256|258,282|284,287|289,292|296,319|322,329|331,341|343,345|347,349|352,352|354,358|360,364|367,371|373,374|377,380|385,386|388,389|393,395|397,398|401,404|407,411|413,413|415,420|422,432|434,435|437,452|454,457|459,462|465,465|471,504|506,506|512,512 ??EEGGGGGGGGTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHTT??TT?TTTS?GGGTT?SSHHHHHTTT??B?TTS?BTT??SS????S--------?SHHHHHHHHHHHHHHHHHHHHHHH---HT??-?GGGB?TTT?SB???HHHHHHHHHHHHHHHHHHHHHHTTTSTTS??EEE?---?TTSSS?EEE??????SGGGGSTT?HHH----------HHHHHHHHHHHHHHHHHHHHHS??BHHHHHHTT?S?HHHHHHHHHHHHHHHHHHHHHHHHH?BTTB?HHHH???HHHHHTTHHHHHHHHHHHHHHHTT??HHHHHHHS?HHHHHHTBGGG?TTS?BTT??S?GGGTT?EEEEE??EEEEE?TT??EEEE????TT?SS???EEE?TT??EEEE??SSGGG?S?BHHHHT?EEEEESSTTTT?EE?SHHHHHHHHHHHTTBS?EEEE?TTTT??S?????HHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTT?B?????S???????????? 3PRR|B PF00423.14_HN_seed 21 662 !Q:0,175|178,179|189,190|193,193|197,197|201,201|204,204|206,213|215,219|221,225|230,232|246,246|259,259|261,266|268,269|281,281|284,285|297,297|300,301|303,303|305,305|321,322|324,324|331,331|334,336|343,343|347,347|354,354|361,366|374,374|377,378|394,394|406,412|415,418|420,422|436,436|442,443|453,453|456,457|467,469|474,474|476,478|483,484|495,495|497,497|500,501|511,511|514,514|518,524|526,526|534,536|540,541|546,547|549,556|559,560|563,567|570,570|574,574|576,577|584,584|591,591|598,598|601,601|603,603|605,605|609,610|613,614|659,659|661,661 Q:176,177|180,188|191,192|194,196|198,200|202,203|205,205|214,214|220,220|226,229|233,245|247,258|260,260|267,267|270,280|282,283|286,296|298,299|302,302|304,304|306,320|323,323|325,330|332,333|337,342|344,346|348,353|355,360|367,373|375,376|379,393|395,405|413,414|419,419|423,435|437,441|444,452|454,455|458,466|470,473|475,475|479,482|485,494|496,496|498,499|502,510|512,513|515,517|525,525|527,533|537,539|542,545|548,548|557,558|561,562|568,569|571,573|575,575|578,583|585,590|592,597|599,600|602,602|604,604|606,608|611,612|615,658|660,660 --------------????????????--------------?????????????-----------???????????????????????-----------------------??????-------------------------?????-------------------???????????SS??GGGTTTSSS??EE?SSS?GGG?EE?S?-------B?????S--???SSSS?--EEEEEEEEESSSE-EEEEEEEBTTTB?T------T??EEEEEEEEEEE?TT??EEEEEEEEEEE?SS??B?S?EEEEETTEEEEEEEB??S?HHHHTT?SS???EEEEEE?TTS?EEEEEE?TTTTTT------TEEEEEE?BS??EEETTEEEEEEEEEE?TTSHHHHTTTT???????SS????S?--HHHHHHHHHHTTS?GGGTS??EEEEEEEEE?SS--SSSEEEEEE???TTTS?B???EEEE--EETTEEEEEE?S?SS??EEEEEEEEE?SS?EEE?------S?EEEEEEE???STT--SSTT??S????????EE??EE?----EE?TTS?B??EEEEEE?SSSSSB?EEEEEE?SS?B?S?EES?-SS??EEEEEEEEEEEETTTTEEEEEEEEEEEETTTEEEEEEEEEEEEE?S? 3INB|A PF00424.13_REV_seed 13 118 !Q:0,9|27,36|67,117 Q:10,26|37,66 -?????-???HHHHHHHHHHHHHHHSS-???????-?TTTHHHHHHHHHHHHHHHHHHHHHHHHTTT???-????????????????????????????-----------???????? 2X7L|M PF00425.13_Chorismate_bind_seed 163 476 !Q:0,0|15,15|17,18|23,26|31,33|42,43|45,46|49,55|57,65|75,80|82,82|84,85|92,104|108,112|114,139|143,144|150,150|154,170|172,173|178,191|196,197|202,204|206,209|211,216|221,245|247,252|263,263|286,289|291,294|296,308|319,323|336,336|339,340|343,345|347,348|356,356|358,358|373,376|383,383|385,391|393,393|396,396|407,407|410,421|428,428|434,436|440,447|449,450|460,460|463,464 Q:1,14|16,16|19,22|27,30|34,41|44,44|47,48|56,56|66,74|81,81|83,83|86,91|105,107|113,113|140,142|145,149|151,153|171,171|174,177|192,195|198,201|205,205|210,210|217,220|246,246|253,262|264,285|290,290|295,295|309,318|324,335|337,338|341,342|346,346|349,355|357,357|359,372|377,382|384,384|392,392|394,395|397,406|408,409|422,427|429,433|437,439|448,448|451,459|461,462|465,475 ?HHHHHHHHHHHHHH-H--HHTS---?SEEE---EEEEEEEE--E--EE?------T---------HHHHHHHHH------H-S??SEEEEE-------------EET-----T--------------------------EEE--EEEES?EEE-----------------E--EETT--------------EEEE??EEEE---E----E?----?SSHH-------------------------H------HHHHHHHHHT?HHHHHHHHHHHHHHHHHHHTTB---?T----T?-----------?EEEEEEEEEE----?SSEEEEEEEEEE-EB-?TT-??H--HHHHHHH?S?GGGSEESHHHHHHH----HHHHSS-S-------B?TT-TTEEEEEEET-TS-----?------EEEEEE?SEEEE---ETT--------E--EEEEEEEEE?TT??HHHHHHHHHHH 3HWO|A PF00426.13_VP4_haemagglut_seed 9 790 !Q:0,0|28,29|32,64|69,74|79,81|89,91|100,102|104,104|108,108|116,116|140,141|158,159|170,171|179,179|192,192|199,199|202,202|206,206|213,213|232,259|267,270|285,286|293,293|298,298|307,307|332,332|339,340|346,346|355,355|358,358|367,368|384,384|386,387|392,394|397,399|403,405|410,410|417,418|426,426|429,429|436,437|443,443|446,446|454,456|458,460|471,471|473,473|488,490|494,497|501,505|524,525|536,538|547,549|586,586|590,595|600,601|610,612|614,615|618,618|639,640|643,643|645,645|661,661|663,665|684,685|689,689|693,694|698,698|702,703|706,707|711,717|729,730|732,733|736,736|748,750|761,761|773,773|789,789 Q:1,27|30,31|65,68|75,78|82,88|92,99|103,103|105,107|109,115|117,139|142,157|160,169|172,178|180,191|193,198|200,201|203,205|207,212|214,231|260,266|271,284|287,292|294,297|299,306|308,331|333,338|341,345|347,354|356,357|359,366|369,383|385,385|388,391|395,396|400,402|406,409|411,416|419,425|427,428|430,435|438,442|444,445|447,453|457,457|461,470|472,472|474,487|491,493|498,500|506,523|526,535|539,546|550,585|587,589|596,599|602,609|613,613|616,617|619,638|641,642|644,644|646,660|662,662|666,683|686,688|690,692|695,697|699,701|704,705|708,710|718,728|731,731|734,735|737,747|751,760|762,772|774,788 ?HHHHHHHHHHTTHHHHHHHHHHHHHSS??EE?????????????????????????????????EEEE-----?SEEE???TTEEEEE???SSEEEEEE---E?SSS?EEEEEEE?SSEEEEEEEEEETTEEEEEEEEE??SSSEEEEEEEESSTTS??EEEEEEEESS??EEEEEET-TEEEEEEEETTS?EEEEEE?TT-GGG?EEEESS?EEEEEGGGHHHHHHHHHH????????????????????????????EEEEESS????EEEEEEEEEEEEEE??EEEEEE?SSSS?EEEEEEEE?EEEEEEEEETTEEEEEEEEEEEES?EEEEEE??SSTTS?EEEEEEEE?TT?EEEEEEEE??HHHHHTTSEEEEEEE-E??EEEE???EE???SSS???EEEE?EEEEEE??EEEEEEE?SS?EEEEEE??EEEEE?SS?EEETTSS???B?--SEESSSTTTT?S?EEEEEEEEEEEEEE???GGG????TTS?????SHHHHHHHHHHHHHHHTT??SHHHHHTTSS???HHHHTSSS???SSHHHHHHHHTHHHHTTSHHHHHHHHHHHHHHHHHT?GGG??????SSSS??TTTHHHHH???S??SS?TTHHHHHHHHHHHHHHHTTT??BS-S?HHHHHHHHHHHHTTS?S???TTTHHHHHHHHHHTSSSS??EEE?SSS??EEE?SSS??EE??SSS???????HHHHHHHHHTS??B??SS?HHHHHHHHHSS???HHHHHHHHHT?HHHHHHHHHSS?STHHHHHHHHHHHTT? 3TAY|A PF00427.16_PBS_linker_poly_seed 152 139 !Q:0,1|4,5|11,12|20,25|27,27|35,39|44,44|51,51|53,53|66,66|68,68|76,76|92,93|110,110|121,121|129,129|134,138 Q:2,3|6,10|13,19|26,26|28,34|40,43|45,50|52,52|54,65|67,67|69,75|77,91|94,109|111,120|122,128|130,133 ??SS??HHHHH--HHHHHHS?---??S?TTSSSSS??--?HHHH-HHHHTT?S?HHHHHHHHHTSS?S?SSTTTSS?HHHHHHHHHHHHTSS??SSHHHHHHHHHHHHHT?HHHHHHHHHH?HHHHHHH?SSEE????? 2KY4|A PF00428.14_Ribosomal_60s_seed 107 126 !Q:2,2|15,19|32,33|35,37|43,125 Q:0,1|3,14|20,31|34,34|38,42 SS?HHHHHHHHHHTT?-???HHHHHHHHHHTT--T?-?HHHHT????????????-----------?????????????????????????????????------???-????--???-??---?? 2W1O|A PF00429.14_TLV_coat_seed 16 732 !Q:0,24|34,35|39,39|52,56|58,63|72,73|78,78|81,82|85,88|90,91|95,95|98,100|103,103|110,111|114,115|133,133|136,137|143,143|146,147|149,150|156,157|163,165|170,172|175,179|184,187|190,190|199,218|231,233|240,240|246,247|252,252|259,260|262,263|265,265|268,269|277,311|314,374|377,387|389,529|531,546|548,731 Q:25,33|36,38|40,51|57,57|64,71|74,77|79,80|83,84|89,89|92,94|96,97|101,102|104,109|112,113|116,132|134,135|138,142|144,145|148,148|151,155|158,162|166,169|173,174|180,183|188,189|191,198|219,230|234,239|241,245|248,251|253,258|261,261|264,264|266,267|270,276|312,313|375,376|388,388|530,530|547,547 ------------------------?EEEEEEEEE?-TTS?EEEEEEEEEETT?????B----??BHHHHHTT??GGGS?TT??TT????S??BTT?TT???TT?BGGGGS??TT??SSSSSHHHHHHHHHHHH?TT??EEEEE?TT??T--THHHH??GGGTT?--SSTT???EE-----ESTT????SS?SEEEEESS?-------------------HHHHHHHHHTTS???BEEEEE?HHHHH??GGGT?EEEEEE--E??T-TT??EEEEEEE-----------------------------------EE-------------------------------------------------------------EE---------??G---------------------------------------------------------------------------------------------------------------------------------------------G----------------G--------------------------------??------------------------------------------------------------------------------------------------------------------------------------------------------ 1MG1|A PF00431.15_CUB_seed 29 132 !Q:0,1|4,7|9,9|17,18|24,27|30,30|38,39|42,42|44,45|53,53|56,59|62,69|83,83|91,91|93,97|100,103|106,106|117,119|122,125 Q:2,3|8,8|10,16|19,23|28,29|31,37|40,41|43,43|46,52|54,55|60,61|70,82|84,90|92,92|98,99|104,105|107,116|120,121|126,131 ??EE----E?SSEEEEE?-TTTTS-???TT?EEEEEEE??TT?E--EEEEEEE-EE????TT------??SSEEEEESSSSSS-SSEEEEE?S-----SS????EE?SSSEEEEEEE?-?SS????EEEEEE 1SFP|A PF00432.16_Prenyltrans_seed 69 59 !Q:1,1|14,17|21,21|23,23|28,43 Q:0,0|2,13|18,20|22,22|24,27|44,58 S?HHHHHHHHHTTB?---TTS?B?SSTT?------------???HHHHHHHHHHHHHTT 4GTR|B PF00433.19_Pkinase_C_seed 160 159 !Q:0,145|147,148|152,158 Q:146,146|149,151 ???????????-?---------?---???-???-----------------------------------------------------??????------?????------------------------------?????-------?T--TTT??????? 2ESM|A PF00434.13_VP7_seed 8 329 !Q:0,82|96,97|113,114|117,117|125,125|133,136|146,147|152,153|170,171|175,176|178,180|201,201|205,205|210,210|213,213|230,232|235,235|241,242|257,257|267,274|279,283|290,291|293,293|313,328 Q:83,95|98,112|115,116|118,124|126,132|137,145|148,151|154,169|172,174|177,177|181,200|202,204|206,209|211,212|214,229|233,234|236,240|243,256|258,266|275,278|284,289|292,292|294,312 -----------------------------------------------------??????????????????????????????EEEEEEHHHHHHH??TTHHHHHHHHHHHTT??TT?EEEEEES?HHHHHHS????SSEEEEEEE??GGGT??HHHHHHHHSEEEEEEE??TTT??B???STTEEEEEEEEEEEEEEEEE?TTS?BSSS?TT?GGGSEEEEEEEEEEEE???SS?EEEEE??TTTEEEEEEEEEEE?TTEEEEEES????????SSSS?????TTEEEE??S?HHHHHHHHHHTHHHHHHTT???????????????? 3GZT|B PF00435.16_Spectrin_seed 83 124 !Q:20,20|25,26|28,33|45,47|59,59|69,72|79,79|84,87|89,89|91,93 Q:0,19|21,24|27,27|34,44|48,58|60,68|73,78|80,83|88,88|90,90|94,123 HHHHHHHHHHHHHHHHHHHH-HHHH--T????-?SSHHHHHHHHH---HHHHHHHHHHH-HHHHHHHHH----HHHHHH-HHTT---?S?H---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 3UUN|A PF00436.20_SSB_seed 70 130 !Q:6,7|14,17|21,22|24,24|27,28|39,58|71,71|80,81|84,85|96,96|100,111|119,121|124,124|129,129 Q:0,5|8,13|18,20|23,23|25,26|29,38|59,70|72,79|82,83|86,95|97,99|112,118|122,123|125,128 EEEEEE--EEEESS?--?EEE??S-SS??EEEEEEEEEE---????-----????????EEEEEEEEEEHH-HHHHHHHH??TT?-EEEEEEEEEE-EEE????-?----??EEEEEEE??-SS?EEEE? 2IHE|A PF00437.15_T2SE_seed 23 341 !Q:8,9|13,13|34,36|43,45|62,63|66,67|70,70|78,85|94,95|99,101|103,104|108,109|116,120|125,127|132,164|175,177|185,185|190,190|196,197|205,206|208,209|212,212|220,225|233,233|237,243|247,247|259,260|267,269|285,285|288,288|293,294|309,318|330,331 Q:0,7|10,12|14,33|37,42|46,61|64,65|68,69|71,77|86,93|96,98|102,102|105,107|110,115|121,124|128,131|165,174|178,184|186,189|191,195|198,204|207,207|210,211|213,219|226,232|234,236|244,246|248,258|261,266|270,284|286,287|289,292|295,308|319,329|332,340 HHHHHHHH--HHT?SEEEEEEETTEEEEEEEETT---EEEEEE???GGGHHHHHHHHHHHHT??SS??SS?EEEEEEE???--???EEEEEEEE??TTS--?E--EEE??EESSTT??--?GGGS???HHHH---------------------------------HHHHHHTTSS---SEEEEEE?STTS?HHHHH--HHHHHHH??T--TS?EEEEESS?????-SSSEEEE?BGG-------GTB?HHHHHHHHHHT??SEEEES???SHHHHHHHHHHHHTT?EE-EEEE??SSHHHHHHHHHHHT--------??HHHHHHHEEEE--EEEEEEEEE 1NLZ|A PF00438.15_S-AdoMet_synt_N_seed 115 149 !Q:0,1|10,10|33,51|54,61|81,92|94,94|96,102|104,106|119,119|122,125|128,128|137,137|147,148 Q:2,9|11,32|52,53|62,80|93,93|95,95|103,103|107,118|120,121|126,127|129,136|138,146 ??EEEEEEEE?TTSHHHHHHHHHHHHHHHHHTT?------------------TT?-------EEEEEEEEETTEEEEEEEE------------E?S---????H---HHHHHHHHHHHT?EE----GG-GTEETTTS-EEEEEEEEE?? 1MXA|A PF00439.20_Bromodomain_seed 69 175 !Q:5,12|14,16|23,24|26,26|32,39|49,55|57,60|63,65|72,78|81,83|87,88|90,92|94,128|130,131|149,156|158,159|167,170 Q:0,4|13,13|17,22|25,25|27,31|40,48|56,56|61,62|66,71|79,80|84,86|89,89|93,93|129,129|132,148|157,157|160,166|171,174 HHHHH--------H---HHHHST--T?GGGSS??-----?TTTSTTHHH-------H?---SS???HHHHHH-------HH---HTT??S---S-----------------------------------H--HHHHHHHHHHHHHHHHH--------S?-TTSHHHH----HHHH 4A9L|A PF00440.18_TetR_N_seed 109 49 !Q:10,10|13,13|17,18|28,29|37,37|39,39 Q:0,9|11,12|14,16|19,27|30,36|38,38|40,48 HHHHHHHHHH-HH?STT??HHHHHHHHT??HHHHHHH?S-SHHHHHHHH 3Q3S|A PF00441.19_Acyl-CoA_dh_1_seed 58 179 !Q:10,10|40,42|47,47|71,71|81,83|89,99|106,106|132,138|140,140|145,146|162,162|164,164|168,168 Q:0,9|11,39|43,46|48,70|72,80|84,88|100,105|107,131|139,139|141,144|147,161|163,163|165,167|169,178 TBHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHH?--BSSS-SBGGGSHHHHHHHHHHHHHHHHH-HHHHHHHHH---HHHTT???--------HHHHHH-HHHHHHHHHHHHHHHHHHHHGGGGG-------S-TTSS--HHHHHHHHGGGGTTT-S?HHH-HHHHHHHHHH 1UKW|A PF00443.24_UCH_seed 53 1596 !Q:0,1|4,6|9,9|22,23|29,29|34,79|82,84|90,96|99,99|103,103|107,259|275,297|302,303|306,398|410,411|414,420|424,426|443,444|446,446|449,512|516,516|526,527|534,535|539,540|545,545|558,559|564,565|569,569|573,574|576,576|581,980|992,992|996,996|1000,1000|1011,1011|1021,1022|1024,1024|1031,1032|1034,1038|1041,1041|1043,1044|1047,1050|1054,1056|1060,1066|1069,1069|1071,1072|1074,1077|1081,1081|1083,1084|1087,1440|1452,1460|1464,1464|1473,1481|1484,1513|1517,1523|1535,1548|1550,1552|1556,1556|1558,1587|1596,1596 Q:2,3|7,8|10,21|24,28|30,33|80,81|85,89|97,98|100,102|104,106|260,274|298,301|304,305|399,409|412,413|421,423|427,442|445,445|447,448|513,515|517,525|528,533|536,538|541,544|546,557|560,563|566,568|570,572|575,575|577,580|981,991|993,995|997,999|1001,1010|1012,1020|1023,1023|1025,1030|1033,1033|1039,1040|1042,1042|1045,1046|1051,1053|1057,1059|1067,1068|1070,1070|1073,1073|1078,1080|1082,1082|1085,1086|1441,1451|1461,1463|1465,1472|1482,1483|1514,1516|1524,1534|1549,1549|1553,1555|1557,1557|1588,1595 ??EE???SS?HHHHHHHHHHHT--STTHH-HHHH----------------------------------------------TT---GGGGT?-----?SS?TTS?TTH---------------------------------------------------------------------------------------------------------------------------------------------------------HHHHHHHHHHHHHHS----------------------?EEEE??HH---------------------------------------------------------------------------------------------HHHHHHHHBGG--GT-------SSS???HHHHHHHHHHHHHHHT??S?SS????????--------------------------------------------------------TTS?HHHHHHHHH--HHHHHH??SHH--HHHH?EEEEEEEEETTT??EEEE??EES?EEE??S?SSEE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHHHHHHHHTS?EEE?GGG?EEETTTTEEE?EEEEEEEEE??S-EEEEEE??E-----EE?S--SS----EEE???EEE??-----SS?B??G----GGB?S??TT??---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?BEEEEEEEEES-?-------TTT?EEEEEEEE---------TT------------------------------TTE-------EEEEETTEEEE??------------G---GGS-S?-----------------------------TTEEEEEE- 3MHH|A PF00444.13_Ribosomal_L36_seed 108 47 !Q:0,1|5,12|16,16|23,28|35,36|42,43|46,47 Q:2,4|13,15|17,22|29,34|37,41|44,45 ??EES??---???SSS?EEEEET------TEEEEE?-SSTTS??EE?- 2ZJQ|4 PF00445.13_Ribonuclease_T2_seed 116 408 !Q:0,0|2,10|12,12|17,27|30,30|38,54|57,67|69,72|74,74|76,77|80,85|91,91|95,111|114,121|123,147|150,159|165,180|191,193|197,199|202,206|223,261|274,275|279,279|288,288|290,293|300,308|322,326|328,329|331,332|339,366|370,370|372,373|386,398|404,405 Q:1,1|11,11|13,16|28,29|31,37|55,56|68,68|73,73|75,75|78,79|86,90|92,94|112,113|122,122|148,149|160,164|181,190|194,196|200,201|207,222|262,273|276,278|280,287|289,289|294,299|309,321|327,327|330,330|333,338|367,369|371,371|374,385|399,403|406,407 ?S---------E-EEEE-----------EE?HHHHSSS-----------------SS------?????T----T?S??SS?-----EEEEE-EEE----------------?TT--------S?-------------?-??----???TT??----??--GGGGG----------------GGHHHHHHHS???SSS???SH-----HHHHHHHHHTGGGTTS?--------------------------------------HHHHHHHHHHHH--HHH?HHHHHHHT-T???-EEEEEE---------EHHHHHHHHHHHH-----S--S??EEEEEE?---------------------------TTS?E--EEEEEEEEEETT-------------SSSEE??SS 2Z70|A PF00447.12_HSF_DNA-bind_seed 114 206 !Q:11,21|23,34|43,45|48,48|50,52|58,60|70,71|74,76|80,82|87,94|103,103|108,108|110,111|117,117|120,165|170,170|173,176|182,190|196,197|199,201|205,205 Q:0,10|22,22|35,42|46,47|49,49|53,57|61,69|72,73|77,79|83,86|95,102|104,107|109,109|112,116|118,119|166,169|171,172|177,181|191,195|198,198|202,204 HHHHHHHHHHH----------?T------------TTTTTEEE?--TT-S---SEEEE??-HHHHHHHHH--HH---HSS???HHHH--------HHHHHHTT?EEEE?S??SSSSS?SS?-----------------------------?---------------EEEE?TT--?-BTTBG---------GGTTT--S???TTS? 1FYL|A PF00448.17_SRP54_seed 55 221 !Q:0,0|7,8|11,12|30,32|34,35|42,42|45,45|61,61|65,69|73,77|94,96|104,107|109,109|128,130|133,134|152,152|162,166|172,172|176,176|178,178|190,192|198,198|203,203|209,210|220,220 Q:1,6|9,10|13,29|33,33|36,41|43,44|46,60|62,64|70,72|78,93|97,103|108,108|110,127|131,132|135,151|153,161|167,171|173,175|177,177|179,189|193,197|199,202|204,208|211,219 ?EEEEEE??TT--SSHHHHHHHHHHHHHHT---T??EEEEEE?TT?HHHHHHHHHHHHHHT?EEE?---?STT?---?HHHHHHHHHHHHHHTT--?SEEEEEE????S?HHHHHHHHHHHHHHGGGT--?TT??SEEEEEEEGGGHHHHHH-HHHHHHHHS-?-??EEEEE?GGG?S?TTHHHHHHHHH???EEEEE?SSSG-GGEEE??HHHHHHHHT? 2Q9B|A PF00449.15_Urease_alpha_seed 117 166 !Q:0,0|12,18|21,21|25,25|30,30|34,35|38,38|40,46|48,59|61,65|78,81|85,91|93,95|108,108|128,128|131,131|135,135|138,155|158,159|162,162 Q:1,11|19,20|22,24|26,29|31,33|36,37|39,39|47,47|60,60|66,77|82,84|92,92|96,107|109,127|129,130|132,134|136,137|156,157|160,161|163,165 ?EEEHHHHHHHH???----TT?EEE?TTSS?EEE??EE?S------?T------------T?????STTSSSSBTTTB????GGG-------S?--SEEEEEEEEEET-TEEEEEEEEEETTEEEEEE?EE?TTT?SS??----------------EE??TT?EEE 1FWI|C PF00450.17_Peptidase_S10_seed 67 665 !Q:2,5|8,12|15,18|25,31|33,33|35,37|48,53|56,60|65,66|72,73|78,78|82,82|94,99|103,103|105,105|109,109|112,112|123,124|131,131|134,135|138,150|153,172|190,190|195,198|202,204|227,227|229,244|247,247|256,257|261,266|276,280|289,290|305,331|335,336|339,341|356,370|374,386|388,389|392,392|396,397|400,401|413,429|432,434|436,436|442,447|456,456|461,462|465,467|473,474|487,492|496,499|502,502|504,504|507,514|518,518|520,522|531,533|540,542|552,552|556,556|567,570|572,574|586,605|609,609|620,627|630,631|640,641|644,645|650,650 Q:0,1|6,7|13,14|19,24|32,32|34,34|38,47|54,55|61,64|67,71|74,77|79,81|83,93|100,102|104,104|106,108|110,111|113,122|125,130|132,133|136,137|151,152|173,189|191,194|199,201|205,226|228,228|245,246|248,255|258,260|267,275|281,288|291,304|332,334|337,338|342,355|371,373|387,387|390,391|393,395|398,399|402,412|430,431|435,435|437,441|448,455|457,460|463,464|468,472|475,486|493,495|500,501|503,503|505,506|515,517|519,519|523,530|534,539|543,551|553,555|557,566|571,571|575,585|606,608|610,619|628,629|632,639|642,643|646,649|651,664 TT---?SS?---?SS---?EEEEEE-------E?S---TTEEEEEEEE----??SS----?GGGS-?EEEEE??TTTB?THH-HHHTTTSSEEE?-----TTS-S?EEE?TT?GGGSSEEEEE??STTSTT?EE--SS?--------????BH--------------------HHHHHHHHHHHHHHHHH-SGGG----TTS--?EEEEEETTHHHHHHHHHHHHTT?T----------------TS?EEEEEEES??SBH------HHHHHHHHH-----HHHHTTSS?-HHHHHHHHHHHEET---------------------------TEE??SS???HHHHHHHHHHHHHH---------------HSS-------------S??TT?TTS??TT??SSSEEEETTEE-----------------EE???S?SSTTS??????GGGHHHHT?EEEE??TT???HHHHH--HHTSHHHHHHTT??----TTS????SB?H-HH--------HHH?B???SBSHHHHH---HHHHHT-??EEEEEEETT?SSS?HHHHHHHHHH----T???EEEEEEEEEEE----?---------------TTS?EEEEEEEEEE--------SS--EEEEEETT??SS--HHHH?HHHHHHHHHHHHTT 1WPX|A PF00451.14_Toxin_2_seed 48 34 !Q:2,2|11,11|19,23|32,33 Q:0,1|3,10|12,18|24,31 EE?SSHHHHHH-HHHHHTS????-EEETTEEE?? 1Q2K|A PF00452.14_Bcl-2_seed 72 143 !Q:11,11|14,16|25,28|31,34|38,41|53,66|83,98|105,108|112,114|127,127|140,140 Q:0,10|12,13|17,24|29,30|35,37|42,52|67,82|99,104|109,111|115,126|128,139|141,142 HHHHHHHHHHH?SS?--SHHHHHHH??-?TT?--?HHH----HHHHHGGGGTT-----------???HHHHHHHHHHHHHHHH----------------HHHHTT?---TTH---HHHHHHHHHHHH-HHHTHHHHHHTT-HH 3KZ0|A PF00453.13_Ribosomal_L20_seed 129 124 !Q:0,7|9,10|25,25|27,27|34,34|77,79|81,83|95,95|97,106|111,113|116,116 Q:8,8|11,24|26,26|28,33|35,76|80,80|84,94|96,96|107,110|114,115|117,123 ???---??T--TTHHHHHHHHHHSS?S?STHHHH?SGGGTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS---S--?HHHHHHHHHHH?S?------???STTT???SS?HHHHHHH 2ZJQ|N PF00454.22_PI3_PI4_kinase_seed 43 480 !Q:2,2|11,11|14,15|25,51|69,78|82,82|86,86|91,110|120,120|130,132|144,144|151,177|193,193|195,195|205,205|209,215|221,284|305,309|316,352|357,358|362,382|384,384|388,388|392,392|396,399|402,404|406,413|420,427|458,466|472,472 Q:0,1|3,10|12,13|16,24|52,68|79,81|83,85|87,90|111,119|121,129|133,143|145,150|178,192|194,194|196,204|206,208|216,220|285,304|310,315|353,356|359,361|383,383|385,387|389,391|393,395|400,401|405,405|414,419|428,457|467,471|473,479 EE-EEEEESSS?TH--HHHHHHHHH---------------------------HHHHHHHHHSHHHHHTT---???????EEE?SSS?EEEE------------------??TTEEEHHHH-HHHHHHHTT-??TTHHHHHHHHH?TTGGGS--------------------------?HHHHHHHHHHHHTTS?S?HHHHHHHHH?SSS-------HHHHH----------------------------------------------------------------HHHHHHHHHHHHHHHHHHHT?????TTSEEE-------------------------------------ETTT??EEE??-----------------??S?TTH-HHH?SSS????SS???H--------HHHHHS-------?SSTTTTHHHHHHHHHHHHHHHTHHHHHHHH---------HHHHS?GGGGGGT 4FLH|A PF00456.16_Transketolase_N_seed 12 343 !Q:0,0|21,21|23,24|42,45|48,48|51,51|54,55|77,78|80,81|90,91|95,95|97,98|101,102|109,110|112,114|123,125|141,141|146,151|157,157|178,178|188,188|200,203|205,205|214,214|220,220|225,225|239,240|243,243|250,251|256,256|269,271|284,288|291,293|301,302|306,307|326,326|340,342 Q:1,20|22,22|25,41|46,47|49,50|52,53|56,76|79,79|82,89|92,94|96,96|99,100|103,108|111,111|115,122|126,140|142,145|152,156|158,177|179,187|189,199|204,204|206,213|215,219|221,224|226,238|241,242|244,249|252,255|257,268|272,283|289,290|294,300|303,305|308,325|327,339 ?HHHHHHHHHHHHHHHHHHHT?S??HHHHHHHHHHHHHHHHT????TT?TT?TT??EEEESSGGGHHHHHHHHHHHT?-S??HHHHTTTT--STT?S??SS??TTTSTT??S???STTHHHHH---HHHHHHHHHHHHHHH?BTTB??????EEEEE?HHHHHSHHHHHHHHHHHHTT?TTEEEEEEE?SEETTEEGGGT????H-HHHHHHTT?EEEEE-EETT?HHHHHHHHHHHHH??SS?EEEEEE??TTTT?TTTTTSGGGTSS???HHHHHHHHHHHT??-??TT???HHHHHHH??HHH--HHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHT??? 2BEU|A PF00457.12_Glyco_hydro_11_seed 12 204 !Q:12,12|14,16|22,22|33,34|36,37|48,57|60,60|70,70|100,100|105,106|130,131|135,135|149,150|154,161|177,181|195,195 Q:0,11|13,13|17,21|23,32|35,35|38,47|58,59|61,69|71,99|101,104|107,129|132,134|136,148|151,153|162,176|182,194|196,203 EEETTEEEEEEE?S???EEEEE?STTEEEEEES--S??EEEEEEEESS??--------SS?EEEEEEEEE-EESSEEEEEEEEEETTTEEEEEEEEESSS?TTTT-?EEEEEEEETTEEEEEEEEEEEEE??TTS-SEEEEEEEEEESS??SSE--------EEEHHHHHHHHHTTT????-EEEEEEEEEEEES?EEEEEEEE 3RI9|A PF00458.15_WHEP-TRS_seed 65 65 !Q:19,20|23,24|26,26|42,44|50,51|53,53|56,64 Q:0,18|21,22|25,25|27,41|45,49|52,52|54,55 HHHHHHHHHHHHHHHHHTT??HH--H-HHHHHHHHHHHHHHH---HHHHS??S?SS?--?--?-- 2Q5I|A PF00459.20_Inositol_P_seed 59 503 !Q:7,7|9,15|21,21|33,38|40,43|48,56|61,63|65,66|68,68|82,85|90,94|97,97|100,101|106,106|112,148|151,152|161,161|169,183|185,186|195,200|213,219|221,236|239,241|243,245|253,260|262,262|265,266|269,271|274,283|286,305|309,309|311,312|315,318|320,327|333,334|337,338|350,362|366,367|369,369|371,374|376,376|380,381|393,394|400,401|403,410|426,440|444,445|450,459|461,462|465,465|467,468|475,481|489,491|496,502 Q:0,6|8,8|16,20|22,32|39,39|44,47|57,60|64,64|67,67|69,81|86,89|95,96|98,99|102,105|107,111|149,150|153,160|162,168|184,184|187,194|201,212|220,220|237,238|242,242|246,252|261,261|263,264|267,268|272,273|284,285|306,308|310,310|313,314|319,319|328,332|335,336|339,349|363,365|368,368|370,370|375,375|377,379|382,392|395,399|402,402|411,425|441,443|446,449|460,460|463,464|466,466|469,474|482,488|492,495 HHHHHHH-H-------HHHHH-HHHHHHHHHTT------S????EESS---------STTS---E--E?HHHHHHHHHHHHH----HHHH?----TT?EE--EEHH-HHHTT?-----------------------????--------?SS-?EEEEEEEE?HHHHHHT?--------------S??EEEEEEEE------TTEEEEEEEEET-------T----------------TT---E---EEEEETT--------T-EE--EE---TT----------EE---?--??????-------?GGG?E--EE????S?-----??HHHHH--HH--HHHHHHHHTTT------------?SEE--E-B?---S?HHH--HHHHHHHTSSS--EEEEE--S------??HHHHHHHHHHHHHTT--------------?EEE-?TTSS-------???T--TS-S--EEEEES-------SHHHHHH---HHHH??-???? 1FJ6|A PF00460.15_Flg_bb_rod_seed 16 32 !Q:22,31 Q:0,21 HHHHHHHHHHHHHHHHHHHHHH????-????? 3A69|A PF00462.19_Glutaredoxin_seed 279 98 !Q:7,7|24,27|32,41|49,51|53,55|66,77|79,79|83,83|87,89|91,91|95,95 Q:0,6|8,23|28,31|42,48|52,52|56,65|78,78|80,82|84,86|90,90|92,94|96,97 EEEEESB?SSSBSSHHHHHHHHHH----HHTT--??----?-EEEEGGG?--H---HHHHHHHHHH------------T?SSS?EEE---E-TTE-EE 3GRX|A PF00463.16_ICL_seed 7 540 !Q:16,18|21,21|29,30|33,37|58,59|65,66|78,78|80,80|84,84|92,93|96,99|102,102|104,104|106,106|136,136|140,141|146,154|159,159|162,162|181,181|187,187|190,190|193,201|205,206|226,228|234,235|244,244|247,247|258,259|263,266|278,280|296,296|299,299|313,316|318,318|333,334|337,339|352,355|361,362|365,366|370,371|387,387|392,394|397,398|413,413|416,416|422,423|427,427|433,433|437,437|477,477|491,493|499,499|522,539 Q:0,15|19,20|22,28|31,32|38,57|60,64|67,77|79,79|81,83|85,91|94,95|100,101|103,103|105,105|107,135|137,139|142,145|155,158|160,161|163,180|182,186|188,189|191,192|202,204|207,225|229,233|236,243|245,246|248,257|260,262|267,277|281,295|297,298|300,312|317,317|319,332|335,336|340,351|356,360|363,364|367,369|372,386|388,391|395,396|399,412|414,415|417,421|424,426|428,432|434,436|438,476|478,490|494,498|500,521 HHHHHHHHHTSGGGGG???SS?HHHHHHH??SS?-???THHHHHHHHHHHHHHHHHHT??EEEEB??SHHHHHHHHHH?S?EEE?HHHHHHH??TT????SS?S?S?TTHHHHHHHHHHHHHHHHHHHHHHHHHSS?HHH--HTTS-????????EEEE?TT?SSSHHHHHHHHHHHHHTT?SEEEE?SB?TT?????????EEE??HHHHHHHHHHHHHHHHHTT???EEEEE??GGGEEEES?TT?GGGGGGEEEE??TTS--??HHHHHHHHHHS???SHHHHHHHHHHHHHS?EE?SHHHHHHHHHTSS---?S?HHHHHHHHHHHHTT??HH---HHHHHHHHHHSS????BTTSS??TT??EEE??SHHHHHHHHHHHTTS?SEEE???SS??HHHHHHHHHHHHHH?TT?EEEEE??SSS?GGGTS?HHH-HHSHHHHHHHHTEEEEEETTHHHHHHHHHHHHHHHHHHH-HTHHHHHHHTHHH---HHHHT?GGGSHHHHHTHHHHHHHHHHHH?????????????????? 4IQD|A PF00464.14_SHMT_seed 12 402 !Q:24,25|28,32|46,49|59,60|80,81|89,91|107,107|110,110|116,116|121,122|126,127|129,129|132,133|135,135|148,148|150,150|154,154|157,157|169,170|176,177|180,181|183,185|198,198|204,204|217,218|223,223|235,237|239,239|246,246|252,252|256,257|261,262|276,277|279,280|322,322|329,329|343,344|359,359|363,364|367,368|370,370|374,375|381,381|389,390 Q:0,23|26,27|33,45|50,58|61,79|82,88|92,106|108,109|111,115|117,120|123,125|128,128|130,131|134,134|136,147|149,149|151,153|155,156|158,168|171,175|178,179|182,182|186,197|199,203|205,216|219,222|224,234|238,238|240,245|247,251|253,255|258,260|263,275|278,278|281,321|323,328|330,342|345,358|360,362|365,366|369,369|371,373|376,380|382,388|391,401 HHHHTHHHHHHHHHHHHHHHHSEE??TT?????HHHHHHHTSGGGT????EETTEESSS??HHHHHHHHHHHHHHHHHTT??TTTEEEE???SSHHHHHHHHHHHHT?TT?EEEEE?GGGT??GGG??B?SS-?B?SHHHHHSEEEEE?B?TTT?SB?HHHHHHHHHHH??SEEEE??SS??S???HHHHHHHHHHTT?EEEEE?GGGHHHHHTTSS??GGGT?SEEEEESSGGG???S?EEEEEE?SEEEE?TTT??EEE??HHHHHHHHHTTTT??S??HHHHHHHHHHHHHTTSHHHHHHHHHHHHHHHHHHHHHHHTT?EETTSS?SSSEEEEEGGGGT??HHHHHHHHHHTTEE?EEE??TT?-S?TTS??EEEEE?HHHHHTT??HHHHHHHHHHH 2VMP|A PF00465.14_Fe-ADH_seed 226 696 !Q:0,2|4,4|6,7|12,14|17,17|19,19|26,27|33,34|36,42|49,53|55,55|58,68|70,70|78,79|82,83|88,88|91,91|95,100|103,103|114,115|119,124|127,128|130,138|161,162|165,166|168,172|177,189|193,195|197,213|219,219|223,224|228,236|243,244|247,249|253,254|258,258|262,262|264,264|268,275|281,281|288,289|311,330|333,348|350,367|371,385|394,396|406,406|409,409|411,411|413,418|422,422|427,428|435,438|440,443|448,451|453,455|457,458|460,462|464,470|480,483|485,485|488,505|514,514|520,521|526,540|543,543|545,547|550,551|558,560|563,568|570,576|579,580|585,585|588,601|609,612|615,616|621,621|623,630|634,636|638,638|640,646|648,651|654,657|659,662|673,673|676,677|681,685|688,690|694,694|696,696 Q:3,3|5,5|8,11|15,16|18,18|20,25|28,32|35,35|43,48|54,54|56,57|69,69|71,77|80,81|84,87|89,90|92,94|101,102|104,113|116,118|125,126|129,129|139,160|163,164|167,167|173,176|190,192|196,196|214,218|220,222|225,227|237,242|245,246|250,252|255,257|259,261|263,263|265,267|276,280|282,287|290,310|331,332|349,349|368,370|386,393|397,405|407,408|410,410|412,412|419,421|423,426|429,434|439,439|444,447|452,452|456,456|459,459|463,463|471,479|484,484|486,487|506,513|515,519|522,525|541,542|544,544|548,549|552,557|561,562|569,569|577,578|581,584|586,587|602,608|613,614|617,620|622,622|631,633|637,637|639,639|647,647|652,653|658,658|663,672|674,675|678,680|686,687|691,693|695,695 ?--S-E--EEES---TT-G-GGGHHH--HHHHT--T?------SEEEEE?---?T-TT?????------S-SHHHHHH--HH--HHTT?EE-EEE??-?-?SS?BHHHHHHHHH--HHH------HT--T?-------?EEEEEESHHHHHHHHHHHHHHH--SS--S?----SGGG?------------BSS???S??-??------------EEEEE?STT??GGG?--------SEEEEE--ET---TTT--EEE-EEE?G-GGS?-------SEEEE?GGGTTT??HHHHHHHHHHHHHHHHHHHHS--------------------TT--??------------H------------------HHH---------------HHHHHHHH---HHHHHHHHH-HH?T-T?-----HHH-HHHH--HHHHHH----H----HHHH----H---H--H???H-------HHHHHHHHH----H-HH-?--------------??HHHHHHHH-HHHHH--HHHG---------------GG?H---HH--HHHHHH---HT------T???----TT??HHHH-HH--------------HHHHHHH----HH--HHHT-T???-?---GGG---G-T---??--G----GG----H----HHHHHHHHHS-GG--GTT----?SS???HHH-H- 1NVB|A PF00466.15_Ribosomal_L10_seed 158 155 !Q:10,11|17,18|22,22|24,25|30,31|33,36|38,39|52,52|55,59|66,67|74,76|80,81|84,99|101,116|118,121|124,126|128,128|131,132|136,137|143,144 Q:0,9|12,16|19,21|23,23|26,29|32,32|37,37|40,51|53,54|60,65|68,73|77,79|82,83|100,100|117,117|122,123|127,127|129,130|133,135|138,142|145,154 SHHHHHHHHH--HHHHH--HHS?S?-EEEE??S----S??STTHHHHTTTTT-TT?---?TTEEEE??TTTTTT---TTT-?TT----------------T-?------?-------S--?-ST---T?SS??EEE--EESSS?-SHHHHHHHHH 3CC7|G PF00467.24_KOW_seed 235 45 !Q:2,2|7,7|14,15|27,37|40,40|45,45 Q:0,1|3,6|8,13|16,26|38,39|41,44 TT?EEEE?SSTTTT-?EEEEEEEETTT-----------TE-EEEE- 2ZJQ|R PF00468.12_Ribosomal_L34_seed 143 46 !Q:0,3|5,8|17,17|24,24|40,40|42,43|46,46 Q:4,4|9,16|18,23|25,39|41,41|44,45 ???-S????SHHHHTTS?STTTTT-SSTTHHHHHHHHHHH?S??SS- 2ZJQ|2 PF00469.15_F-protein_seed 20 245 !Q:0,4|22,99|101,102|105,106|109,110|113,115|130,130|135,135|137,138|154,154|156,156|160,161|163,165|168,168|170,170|176,177|183,183|193,194|198,214|218,219|225,225|231,232|238,238|243,245 Q:5,21|100,100|103,104|107,108|111,112|116,129|131,134|136,136|139,153|155,155|157,159|162,162|166,167|169,169|171,175|178,182|184,192|195,197|215,217|220,224|226,230|233,237|239,242 ?????HHHHHHHHHHHHHHHHS---?????----------???-----?????????-???????----------------????????????????-??B?-EE??TT??BB???HHHHHHHHHHHHHH?SSTT?B??HHHHHHHHHHHHHHH?B?TTS??B???SS?B?BSSTT??EEEEE?SHHHHHHHH--HTT???????????????--TTT??EEEEE?GGGGT??HHHHH?GGGT??- 2NEF|A PF00471.15_Ribosomal_L33_seed 117 75 !Q:0,6|8,11|15,28|33,37|39,40|45,45|47,62|66,70|73,74 Q:7,7|12,14|29,32|38,38|41,44|46,46|63,65|71,72 ?---???B??--EES--------------SSSS?????B??TTSS?S????????--------SSS?????EE?? 2ZJQ|1 PF00472.15_RF-1_seed 100 176 !Q:1,3|6,6|9,11|21,31|38,57|61,61|65,71|74,93|102,102|122,124|126,133|142,156|158,159|166,166 Q:0,0|4,5|7,8|12,20|32,37|58,60|62,64|72,73|94,101|103,121|125,125|134,141|157,157|160,165|167,175 E???GG-GS???GGGEEEEEE-??????????SSSSEE--------------------EEE-EET-------TT?------------------?EEEEEESS?HHHHHHHHHHHHHHHHHHH---H--------HHHHHTTT???????????????E--EEEEET-TTTEEEETT 2B64|Y PF00473.12_CRF_seed 7 44 !Q:0,2|30,34|43,43 Q:3,29|35,42 ???HHHHHHHHHHHHHHHHHHHHHHHHHHH-----HHHHHHTT? 2RMI|A PF00474.12_SSF_seed 10 447 !Q:0,8|37,37|64,68|72,73|84,84|88,89|122,124|144,149|190,190|192,192|196,196|199,213|217,222|229,229|249,249|260,260|287,289|302,313|328,329|369,369|371,374|403,403|405,405|431,431|434,435 Q:9,36|38,63|69,71|74,83|85,87|90,121|125,143|150,189|191,191|193,195|197,198|214,216|223,228|230,248|250,259|261,286|290,301|314,327|330,368|370,370|375,402|404,404|406,430|432,433|436,446 ?????????HHHHHHHHHGGGSSHHHHHHHHHHHHHT?GGGGHHHHHHHHHHHHHHHTHHHHHH-----HTT??SHHHHHHHHT?HHH--HHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHH???HHHHHHHHHHHHHHHHHTT??????HHHHHHHHHHHHHHHHHHHHHHHHHHGGHHHHHHHHHHHH?G-GGS?SS----------??---SSS------GGGGTS?TTHHHHTHHHHHHHHHTTT?SHHHHHHTTS?HHHHHHHHHHHHHHTTTHHHHHTHHH---HHHHHHHHHHHH?----???????TBGGGHHHHHHHTS-?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHT?S?-??HHHHHHHHHHHHHHHHHHHHHHGGGGGG?B?HHHHHHHHHTTTHHHHHHHHHHHHH?TT??HHHHHHHHHHH 3DH4|A PF00475.13_IGPD_seed 146 196 !Q:0,0|2,2|18,18|26,30|34,34|36,37|47,48|61,62|65,66|68,86|97,108|114,115|118,118|124,128|131,131|134,134|138,141|160,160|164,164|170,178|196,196 Q:1,1|3,17|19,25|31,33|35,35|38,46|49,60|63,64|67,67|87,96|109,113|116,117|119,123|129,130|132,133|135,137|142,159|161,163|165,169|179,195 ?S?HHHHHHHHHHHHHHT?EEEEEEE??---TTT?S--HHHHHHHHH--HHHHHHHHHHTT??SB??B-----------------??EEEEETTEEE------------EEEEE??SS?EEEEE--???SS-SE-ETT----EETTHHHHHHHHHHHHHT?EEE-EEEEE??------?HHHHHHHHHHHHHHHHH- 2F1D|A PF00476.15_DNA_pol_A_seed 12 484 !Q:0,0|3,3|6,7|12,13|16,20|22,26|30,30|33,36|39,39|51,55|60,60|77,77|86,87|89,94|107,109|113,115|117,122|125,125|129,133|139,142|145,151|156,157|162,164|167,168|176,176|197,197|205,205|207,208|212,212|225,227|242,243|256,256|276,276|281,281|285,285|299,302|305,311|317,317|321,321|345,345|351,352|356,377|411,419|421,424|458,465|470,470|472,474|477,477|481,481|483,483 Q:1,2|4,5|8,11|14,15|21,21|27,29|31,32|37,38|40,50|56,59|61,76|78,85|88,88|95,106|110,112|116,116|123,124|126,128|134,138|143,144|152,155|158,161|165,166|169,175|177,196|198,204|206,206|209,211|213,224|228,241|244,255|257,275|277,280|282,284|286,298|303,304|312,316|318,320|322,344|346,350|353,355|378,410|420,420|425,457|466,469|471,471|475,476|478,480|482,482 ?TT?SS??TTTS??TT???--B?????TTT?SS????SS?STHHHHHHTSS?????SSSH-HHHHHHHHHHHHHHHH-HHHHHHHT??B---???SSSSTTTTTTTT???SSS???B??????SS?TTT?????TTGGG????SS?------STTS??HHHH???TT--EEEEEEE?TTHHHHHHHHHHHHHSSSTT?STTTTTT?S??TTT?THHHHHHHHHTT???SHHHHHHHHHHHHS??THHHHHHHHHHS?TTHHHHHHHHHHHHHHHHH?SSSS?SSS?HHHHHHHHHSSSS????SS???????HHHHS?SSS?HHHHTTTTTTHHHHHHHHHHHHS?SSSSS??SSS????????????????????-?SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSS???------B????BTTEEEEEEESTTHHHHHHHHHHHHHHHHHHHH--------HHHT?S???HH-HHT?S? 2BDP|A PF00478.20_IMPDH_seed 84 554 !Q:0,3|10,17|22,24|27,31|34,37|40,40|49,52|56,56|59,59|70,70|74,74|76,76|78,78|81,81|84,84|96,229|235,235|238,239|241,245|249,249|251,252|257,257|269,270|274,275|277,278|280,282|288,289|291,292|308,308|310,311|314,314|321,321|329,329|335,336|342,342|345,345|349,349|356,362|378,383|385,390|396,398|411,411|433,433|442,442|444,490|492,493|496,497|499,499|513,513|521,521|531,538|542,553 Q:4,9|18,21|25,26|32,33|38,39|41,48|53,55|57,58|60,69|71,73|75,75|77,77|79,80|82,83|85,95|230,234|236,237|240,240|246,248|250,250|253,256|258,268|271,273|276,276|279,279|283,287|290,290|293,307|309,309|312,313|315,320|322,328|330,334|337,341|343,344|346,348|350,355|363,377|384,384|391,395|399,410|412,432|434,441|443,443|491,491|494,495|498,498|500,512|514,520|522,530|539,541 ????GGGEEE????????GGGS???EE-----SS----SS?EESSSEEE-???TTT?SH-HHHHHHHTTT?EEE-E?S-SS?HH-HHHHHHHHHHT-???????????????????????????????????????????????????????????--------------------??????????????????????????????????????????????????????HHHHT?TT??B----?TTS?B??EEEE?SSTTHHHHHHH--HHH--T--T?--SEEEE??S??SSHHHHHHHHHHHHH?T--TS?EEEEEE?SHHHHHH-HHHTT-?SEEEE?SS?STT?HHHHHH?????--HHHHHHHHHHHHHTT------T----??EEEES???SHHHHHHHHHTT?SEEEESHHHHTBTTSSSEEEE-ETTEEEEE?B??????????------------??????????------?????????B??EE??B?HHHHHHHHHHHHH-HHHHHHT?SSHHHHHHH?------?EEE???????????? 1MEI|A PF00479.17_G6PD_N_seed 117 203 !Q:25,25|27,27|30,30|40,43|56,69|88,89|92,93|110,113|115,115|125,125|127,127|143,148|152,156|162,162|164,164|166,166|184,184|191,192|197,197 Q:0,24|26,26|28,29|31,39|44,55|70,87|90,91|94,109|114,114|116,124|126,126|128,142|149,151|157,161|163,163|165,165|167,183|185,190|193,196|198,202 EEETTTSHHHHHTHHHHHHHHHHTT?S?SS-EEEEEEESS???-HHHHHHHHGGGS??-----------?GGGHHHHHHHHHTEEEEE??SS-?HHHHHHHHHHHHTTTT----T-TTSEEEEEE?S?TTSHHHHHHHHHHHS??----SSS----?EEEEE?S?S?SSHHHHHHHHHHHTTTS?GGGEEE??GGGG?HHHHH 2BH9|A PF00480.15_ROK_seed 14 212 !Q:4,4|14,14|17,18|27,28|31,34|53,53|55,61|76,81|84,84|96,98|108,108|110,110|129,129|131,131|133,135|157,159|163,166|169,171|176,176|179,189|191,191|193,193|197,197|199,199 Q:0,3|5,13|15,16|19,26|29,30|35,52|54,54|62,75|82,83|85,95|99,107|109,109|111,128|130,130|132,132|136,156|160,162|167,168|172,175|177,178|190,190|192,192|194,196|198,198|200,211 EEEE?SSEEEEEEE?TT??EEEEEEEE??SS--??HHHHHHHHHHHHTTTGGG?S-------EEEEEESSEEETTE------EE?SSGGGGGGGTT-??HHHHHHHHH?S?EEEEEHHHHHHHHHHHTS?T-T???EEEEEESSSEEEEEEETTEEE??-TTS????GG---GSBS?TT-----------S?B?TTS?B-SBHHHHHSHHHH 1Z6R|A PF00481.16_PP2C_seed 31 375 !Q:14,15|26,33|63,67|78,78|80,80|84,94|109,110|118,120|125,129|132,137|147,147|151,158|167,167|179,189|192,196|202,202|212,213|216,220|228,248|251,251|254,254|257,257|262,263|267,288|296,298|302,303|307,308|319,319|326,327|342,353|370,371|373,373 Q:0,13|16,25|34,62|68,77|79,79|81,83|95,108|111,117|121,124|130,131|138,146|148,150|159,166|168,178|190,191|197,201|203,211|214,215|221,227|249,250|252,253|255,256|258,261|264,266|289,295|299,301|304,306|309,318|320,325|328,341|354,369|372,372|374,374 EEEEEEEEEEEESS??EEEEEEEEET--------TTEEEEEEEEEEEEESSSHHHHHHHHHHH-----HHHHSSHHHH?S-SSS---------??HHHHHHHHHHHHHH--HHHHHHH---HHHH-----HT?-????EEEEEEEEE?SSE--------EEEEEESS?EEEEEETTEEE-----------EE?????TTSHH-HHHHHHHTT??EE-----TTEETTT---------------------BS?SB?EE?GGGS??TTS---------------------?GGGSSSB???EEE--EEE??TTTEEEEEEE?HHHHTT??HHHHHHHHHHHHTT??---------?HHHHHHHHHHHHHHTT??S?E 3RT0|A PF00482.18_T2SF_seed 340 177 !Q:10,10|13,14|21,22|28,28|30,40|58,62|64,65|67,69|74,89|91,91|94,97|100,101|116,116|136,140|151,174 Q:0,9|11,12|15,20|23,27|29,29|41,57|63,63|66,66|70,73|90,90|92,93|98,99|102,115|117,135|141,150|175,176 HHHHHHHHHH-TT??HHHHHH--HHHHT?S----------?HHHHHHHHHHHHHHHTT?---?H--H---HHHT----------------T?TT----TS-?HHHHHHHHHHHHHT?HHHHHHHHHHHHHHHHHHH-----HHHHHHHHHH------------------------TT 3C1Q|A PF00483.18_NTP_transferase_seed 64 342 !Q:5,6|8,9|20,20|30,32|45,46|57,57|76,85|92,92|95,106|122,122|124,129|136,136|140,140|142,143|155,156|158,161|170,170|172,172|182,188|191,198|206,206|209,209|211,231|237,237|243,243|251,251|253,253|255,258|263,264|277,277|283,284|289,321|324,325 Q:0,4|7,7|10,19|21,29|33,44|47,56|58,75|86,91|93,94|107,121|123,123|130,135|137,139|141,141|144,154|157,157|162,169|171,171|173,181|189,190|199,205|207,208|210,210|232,236|238,242|244,250|252,252|254,254|259,262|265,276|278,282|285,288|322,323|326,341 EEEEE??S??GGGTTTTTSS?GGGSEETTE---ETTHHHHHHHHH--TTEEEEEEEE?TTTHHHHHHHHTTSGGGT---------?EEEEEE?SS??---------?TTHHHHHTHHHHTTS?E------EEEETT?EEE?T--THHHHHHHHHH??S----SEEEEEEE?S?GGGSEEEEE?------TT?------?EEEEEES?SS?S---------------------SSEEE?SEEEE?TTHHHHH-H-T????SSSS??HHHHHHHHHHHT?EEEEE??TTSE---------------------------------EE??SSHHHHHHHHHHHHHH 1HV9|A PF00484.14_Pro_CA_seed 497 313 !Q:8,8|11,13|19,22|34,37|40,70|74,74|81,87|93,95|103,106|110,110|115,120|123,132|135,162|168,171|174,177|187,193|202,221|226,234|238,248|265,266|271,274|281,292|300,300|304,312 Q:0,7|9,10|14,18|23,33|38,39|71,73|75,80|88,92|96,102|107,109|111,114|121,122|133,134|163,167|172,173|178,186|194,201|222,225|235,237|249,264|267,270|275,280|293,299|301,303 EEEEEETT?SS?--HHHHH-???TTSEEEEEETT????TT------------------------------?HHH-HHHHHH-------HHHTT??-SEEEEEE----ETT?HHHH------HH----------HS??------------------------??STHHH----HH----HHHHHHHHH-------THHHHHSS?-------------------HHHH---------HHH-----------HHHHHHHHHHHHHHHS--HHHH----HHHHTT?---------??EEEEEEE?TTT------??? 3E3I|A PF00485.13_PRK_seed 12 222 !Q:6,12|27,28|34,45|52,53|69,69|72,72|81,81|97,98|101,112|115,116|120,123|126,127|130,130|139,139|142,142|144,144|147,147|149,149|153,153|162,162|178,179|181,184|191,191|208,208|219,220 Q:0,5|13,26|29,33|46,51|54,68|70,71|73,80|82,96|99,100|113,114|117,119|124,125|128,129|131,138|140,141|143,143|145,146|148,148|150,152|154,161|163,177|180,180|185,190|192,207|209,218|221,221 EEEEES???????THHHHHHHHHHHHT??EEEEE------------GGGGBS??HHHHHHHHHHHHHHT?TT?STTSGGGB?HHHHHHHHHHHHHHS??EE????????????SS??TTS????EE??SS?SEEEEEES?TT?B?SS?B?GGG?SEEEEEEE?HHHHHHHHHHHTSSS??S????HHHHHH-HHHHHHHHHTGGGGGT?SEEEEEEESS??S 2ZSB|A PF00486.23_Trans_reg_C_seed 362 115 !Q:2,15|32,33|42,43|49,57|76,76|79,81|85,101 Q:0,1|16,31|34,41|44,48|58,75|77,78|82,84|102,114 SB?--------???-?HHHHHHHHHHHHTTTS-?EEHHHHHH--HHTSS??-------TTHHHHHHHHHHHHHHHH?SS---SSS?----------------SSEEEETTTEEEE 1OPC|A PF00488.16_MutS_V_seed 35 289 !Q:0,0|2,3|6,6|10,22|29,30|37,40|42,42|44,47|53,53|57,65|71,72|95,96|105,108|115,127|141,142|145,145|152,155|174,175|179,180|186,186|188,188|198,202|206,214|217,218|226,235|239,239|249,249|253,254|256,256|258,259|269,271 Q:1,1|4,5|7,9|23,28|31,36|41,41|43,43|48,52|54,56|66,70|73,94|97,104|109,114|128,140|143,144|146,151|156,173|176,178|181,185|187,187|189,197|203,205|215,216|219,225|236,238|240,248|250,252|255,255|257,257|260,268|272,288 ?B??EE?SSS------------?EEEEEE??TTHHHH?---S-S????EEEEE?SSS--------?EEEEE??TTSSHHHHHHHHHHHHHHHTTT??BSSSEEEE????EEEEEE?????????????HHHHHHHHHHHHH??TT?EEEEES????SSTTHHHHHHHHHHHHHH--HTT??EEEEE?S?GGGGGHHHH-----STT---------EE--EEEEEEE----------EET-TEEEEEEEE-EES??S-S??HHHHHHHTT?-?HHHHHHHHHHHHHHHTT 2O8E|A PF00489.12_IL6_seed 10 158 !Q:14,16|20,25|27,32|34,42|47,47|52,53|79,79|84,84|109,109|111,115|130,130 Q:0,13|17,19|26,26|33,33|43,46|48,51|54,78|80,83|85,108|110,110|116,129|131,157 HHHHHHHHHHHHHH---HTT??????S??????S?????????GGGT?SSTT??HHHHHHHHHHHHHHHHHHHHHHTTS?STTH-HHHHHHHHHHHHHHHHHHHSSTTT?S?????TTHHHHHHHHHTSS?HHHHHHHHHHHHHHHHHHHHHHHHHHH 1RHG|A PF00490.16_ALAD_seed 165 389 !Q:0,4|19,25|41,43|58,58|60,60|75,76|83,88|91,94|97,97|101,102|104,105|122,122|125,125|133,133|142,142|147,169|173,175|197,197|203,203|205,206|221,221|223,223|236,237|240,240|249,255|257,270|277,277|279,279|281,282|298,298|306,306|321,325|327,327|333,333|346,347|352,353|370,370|383,384|386,386 Q:5,18|26,40|44,57|59,59|61,74|77,82|89,90|95,96|98,100|103,103|106,121|123,124|126,132|134,141|143,146|170,172|176,196|198,202|204,204|207,220|222,222|224,235|238,239|241,248|256,256|271,276|278,278|280,280|283,297|299,305|307,320|326,326|328,332|334,345|348,351|354,369|371,382|385,385|387,388 ?????GGGGTSSHHHHHHH??-????GGGEEEEEEEESSSS--?EEEETTEEEEEEEE-H-HHHHHHHHHHHHHT??EEEEEE?---?-SS--??SS?GGG--G?-TTSHHHHHHHHHHHHS-TT-SEEEEEE?STTTSTTS?SSEE-----------------------SSS--?EEHHHHHHHHHHHHHHHHHHT?SEEEE?S??TTHHHHHHHHHHHT-T?TTSEEEEEEEEB??TT?HHHHHHTT??--???S-------------?STTTSB?T-T-?SHHHHHHHHHHHHHT?SEEEEES?GGGHHHHHHHHHHH-?---S?EEEEE?HHHHHHHHHHHH--TTSS?-HHHHHHHHHHHHHHHT?SEEEETTHHHHH--H-HH 1AW5|A PF00491.16_Arginase_seed 347 607 !Q:0,0|6,6|8,11|13,15|17,18|21,24|26,26|32,37|46,54|56,59|65,65|67,77|83,83|86,121|123,128|132,169|171,172|174,174|178,178|180,182|193,193|195,199|202,203|205,221|223,223|226,247|251,253|265,267|272,291|293,294|301,301|304,308|310,310|312,323|325,325|329,339|341,341|348,350|352,385|390,390|392,392|396,399|408,408|415,416|419,421|423,431|435,437|442,442|444,445|455,456|458,458|460,461|464,466|475,480|482,484|486,489|501,502|506,508|512,513|515,515|517,518|520,520|528,528|532,532|534,536|539,543|547,548|555,555|557,558|560,563|566,566|570,588|600,601|603,603 Q:1,5|7,7|12,12|16,16|19,20|25,25|27,31|38,45|55,55|60,64|66,66|78,82|84,85|122,122|129,131|170,170|173,173|175,177|179,179|183,192|194,194|200,201|204,204|222,222|224,225|248,250|254,264|268,271|292,292|295,300|302,303|309,309|311,311|324,324|326,328|340,340|342,347|351,351|386,389|391,391|393,395|400,407|409,414|417,418|422,422|432,434|438,441|443,443|446,454|457,457|459,459|462,463|467,474|481,481|485,485|490,500|503,505|509,511|514,514|516,516|519,519|521,527|529,531|533,533|537,538|544,546|549,554|556,556|559,559|564,565|567,569|589,599|602,602|604,606 ?SEEEE-E????T---T-?SS-???G-GGHHH------HHHHHGGG??-------S----EETTT?B?----------GGGTS?EE------------------------------------E------EEE-?--------???-------------------------T--T?HHH-H---HHHHHHHHHH-H-----HH--T-----------------T?EE----------------------EEE???GGGHHHHHHHH---HHHH-------------------?S--EEEEEE?SS???-?S?B------------T-TBS----------?S-TTTHHH---H----------------------------------HHHT-T?EEE----EEEEEEEE?SEESST--HH---H---------HHH---HHHT?E--EEEGGGTTT??S-H--HH---HHHHHHHH-----?S---S----EEEEEEEGGGB?-TTT???BSS??S-S-?B?HHHHHHH-HHT-T---TT-----SEE--EEEEEE?B?-G----GG?SSS-------------------HHHHHHHHHHH--H-HHH 1WVB|A PF00493.18_MCM_seed 62 427 !Q:8,9|13,14|25,25|27,28|31,33|36,36|47,55|59,67|69,70|75,75|78,79|90,90|92,92|105,105|112,113|117,117|124,128|132,133|147,147|151,152|175,176|180,180|183,185|192,193|195,196|200,200|205,205|213,213|220,220|224,224|227,231|234,237|248,248|250,251|253,283|286,318|332,347|351,351|367,375|381,382|385,385|387,387|403,403|406,406|409,410|426,426 Q:0,7|10,12|15,24|26,26|29,30|34,35|37,46|56,58|68,68|71,74|76,77|80,89|91,91|93,104|106,111|114,116|118,123|129,131|134,146|148,150|153,174|177,179|181,182|186,191|194,194|197,199|201,204|206,212|214,219|221,223|225,226|232,233|238,247|249,249|252,252|284,285|319,331|348,350|352,366|376,380|383,384|386,386|388,402|404,405|407,408|411,425 HHHHHHTT-?SSS--HHHHHHHHHH?S??SS--?HH-HHHHHHHHTS????-?--?SSS--??--???S??EEEE?SS?-SSHHHHHHHH-T-TSSSSEEEEESS?STTTSS-?EEE?SSSSTT?---?EEE??SSSTTTTSEEEEE?GGG??TTGGGTHHHHTTTSEEEEESSS-?EEE-EE???EEEEEE??S--SSS?TTTS?SSSSSSS?SSGGGG?SEE-EE???-?SS-???HHHHHHHHHT?S??S-------------------------------SS?-------------------------------?TTTTHHHHHHHTT-??????--?----??THH-HHHHHHHHHHHHHHH---------HTSTT??TT?S?TTHHHHHHHHHHHHS?SS?SS??STHHHHHHHHHHHHH? 4FDG|A PF00494.14_SQS_PSY_seed 152 632 !Q:4,4|14,16|40,41|43,61|65,80|82,82|97,149|152,155|158,180|192,202|205,206|216,219|225,260|263,273|278,286|298,299|309,311|313,327|331,337|339,340|345,372|374,378|380,390|408,423|427,429|431,432|434,434|436,436|439,440|443,443|446,453|455,455|457,458|461,465|468,468|472,494|497,497|504,528|548,576|578,579|594,594|600,602|604,604|611,631 Q:0,3|5,13|17,39|42,42|62,64|81,81|83,96|150,151|156,157|181,191|203,204|207,215|220,224|261,262|274,277|287,297|300,308|312,312|328,330|338,338|341,344|373,373|379,379|391,407|424,426|430,430|433,433|435,435|437,438|441,442|444,445|454,454|456,456|459,460|466,467|469,471|495,496|498,503|529,547|577,577|580,593|595,599|603,603|605,610 HHHH?TTHHHHTTT??-TTTHHHHHHHHHHHHHHHHTSTT??S--------------?----HHH----------------H-HHHHHHHHHHHHHT-------------------------------------------??-?------SH----HH-----------------------HHHHHHHHHHT---------??SH--HHHHHHHHH----HHHHH-----------------------?------------SB--------??-SHHH---------HHHHHHHHTHH--HHHHHHHHT---T?-?------------SHH-------H--HHHH----------------------------H-----H-----------HHHHHHHHHHHHTHHHH----------------HHT---T?-B?S?HH--HH-HT--------T-T??HH-----HH-HTT--------------------???HH-HHHHHH-------------------------HHHHHHHHHHHHHGGGGGS-----------------------------S-?HHHHHHHHHHHHHH-HHHHH---H-HHTTTT???----?----????????? 3NPR|A PF00496.17_SBP_bac_5_seed 226 817 !Q:0,0|9,9|11,28|30,32|34,34|38,38|45,45|47,52|54,54|58,59|62,64|71,74|76,80|86,86|97,122|134,146|165,166|180,182|191,259|263,263|271,275|284,286|290,292|295,297|301,301|305,312|315,320|322,344|346,353|355,355|363,370|379,379|384,384|387,389|392,398|406,409|412,412|418,440|444,449|457,457|460,480|483,485|488,488|490,500|512,512|515,515|522,540|542,542|549,550|553,553|555,555|561,562|565,626|639,639|642,642|648,681|683,684|687,687|708,709|712,718|726,728|730,769|776,778|783,784|790,791|795,795|797,797|800,800 Q:1,8|10,10|29,29|33,33|35,37|39,44|46,46|53,53|55,57|60,61|65,70|75,75|81,85|87,96|123,133|147,164|167,179|183,190|260,262|264,270|276,283|287,289|293,294|298,300|302,304|313,314|321,321|345,345|354,354|356,362|371,378|380,383|385,386|390,391|399,405|410,411|413,417|441,443|450,456|458,459|481,482|486,487|489,489|501,511|513,514|516,521|541,541|543,548|551,552|554,554|556,560|563,564|627,638|640,641|643,647|682,682|685,686|688,707|710,711|719,725|729,729|770,775|779,782|785,789|792,794|796,796|798,799|801,816 ?EEESSEEE-E------------------E---E?TTS?EEEEEE?S??????B-TTB??SS???HHHHHH----H-----HHHHH?TTSGGGGGGG??----------------------?-HHHHHTTHHHH-------------EEEEEEEETTEEEEEESS??TTHHHHHTSGGGB???HHHHHHHH---------------------------------------------------------------------HTT?THHHHHS???--SSSEEEEE---EET---TT---EEE-EEE-------?TT--?---S-----------------------S-???----S?SEEEEEE?----?-?HHHHHHHH-HTTS?SB?--SS??-----HHHHHHH----HH?SSEEE-----------------------EEE?---??EEEEEEE?TT---------------------ST---TT-T?----------HHHHHHHHHTS?HH-HHHHHT-------------------T-TTSEEE??SS-S?TTSTT??TT????--?--------------------------------------------------??---HHHHHHHHHHTT?TT?EEEEE----------------------------------E??SS?BTTBTTHHHHHHHHHHHHHT--TT-------EEEEEEE?-?H----------------------------------------HHHHHH---HHTT??SEEEE--EEE?S-SS?THHHHHHHHSHHHHHH 3TCH|A PF00497.15_SBP_bac_3_seed 483 558 !Q:3,3|6,6|8,8|12,12|19,31|42,45|50,53|57,57|60,60|62,68|73,74|76,83|89,89|91,91|97,97|99,99|101,102|104,104|106,106|109,109|111,118|122,123|125,126|128,128|130,140|143,143|145,146|148,152|156,157|165,165|167,298|301,303|305,308|311,313|316,335|337,344|347,347|352,352|355,358|363,365|369,374|377,377|379,392|397,416|418,420|422,422|424,424|431,431|434,441|443,443|448,450|452,452|469,469|473,473|478,499|504,505|509,510|516,516|530,530|538,542|544,544|546,546|549,551|554,554 Q:0,2|4,5|7,7|9,11|13,18|32,41|46,49|54,56|58,59|61,61|69,72|75,75|84,88|90,90|92,96|98,98|100,100|103,103|105,105|107,108|110,110|119,121|124,124|127,127|129,129|141,142|144,144|147,147|153,155|158,164|166,166|299,300|304,304|309,310|314,315|336,336|345,346|348,351|353,354|359,362|366,368|375,376|378,378|393,396|417,417|421,421|423,423|425,430|432,433|442,442|444,447|451,451|453,468|470,472|474,477|500,503|506,508|511,515|517,529|531,537|543,543|545,545|547,548|552,553|555,557 EEE-EE?S-EET-TTEEEE-------------TTEEESHHHH----HHHH----HHH-HH-T?----?-EEEE--E---?---?HHHHH-H-HHHTT-S-S-?E-E?SS?B?------?TTT--T--T-T-----------EE-E-?S-?--?EEE-?EEEEEET-T-----?----------------------------------------------------------------------------------------------------------------?-----?---?---SG---G----GG---TT--------------------S--?-----EE-EETT-SH----HHHH---HHH------HH?S--------------STTE--------------------E---E-E-SSHHHH-HH--------H-HHTT---S?SEEEEEHHHHHHHHHH?GGG?EEEE--------------------??TTTS??EEE??EEETT?SSHHHHHHHHHHH-HHTTHHH-----H-H-HH---HH-HSS 2Q2C|A PF00498.21_FHA_seed 221 171 !Q:6,16|19,19|24,42|44,46|49,49|51,51|54,54|57,59|61,63|69,97|104,109|111,115|118,118|120,120|123,127|130,135|138,138|141,157|161,161|164,164|166,166 Q:0,5|17,18|20,23|43,43|47,48|50,50|52,53|55,56|60,60|64,68|98,103|110,110|116,117|119,119|121,122|128,129|136,137|139,140|158,160|162,163|165,165|167,170 EEEESS-----------TT-SSEE---??--------------S---TT-S?SS?EE---E---EEETT-----------------------------EEEEEE-----?S----?SS?E-EE-----TT------EE?SE-----------------EEE?TT?E-EEET 3UMZ|A PF00499.15_Oxidored_q3_seed 100 281 !Q:9,13|33,34|40,43|70,74|86,120|122,152|163,169|185,195|202,245|254,254|258,261|274,275 Q:0,8|14,32|35,39|44,69|75,85|121,121|153,162|170,184|196,201|246,253|255,257|262,273|276,280 HHHHHHHHH--?-?SHHHHHHHHHHHHHHHHHH--HHHTT---?HHHHHHHHHTHHHHHHHHHHHHHHHH?---?SSTTHHHHHTT?----------------------------------S-------------------------------HHHHHHHHHH-------HHHHHHHHHHHHTTS???????????HHHHHH--------------------------------------------HHTTTSHH-HHH----HHHHHHHHHHHH--HHHHH 4HEA|J PF00500.13_Late_protein_L1_seed 19 534 !Q:0,21|26,26|37,37|39,39|49,49|52,52|56,61|65,65|67,68|72,72|79,81|86,87|89,90|94,94|112,112|114,114|117,119|126,126|131,131|133,134|137,142|144,152|159,160|171,172|180,183|187,189|191,191|193,197|205,206|209,209|212,213|216,216|219,219|224,224|228,228|231,231|238,238|243,243|250,250|253,254|256,256|265,265|274,274|276,279|282,284|289,305|311,315|322,326|330,331|338,338|340,341|346,346|353,354|361,361|364,366|374,374|376,381|384,385|412,413|424,424|432,438|441,442|453,453|458,458|460,469|475,476|481,481|484,485|488,488|503,533 Q:22,25|27,36|38,38|40,48|50,51|53,55|62,64|66,66|69,71|73,78|82,85|88,88|91,93|95,111|113,113|115,116|120,125|127,130|132,132|135,136|143,143|153,158|161,170|173,179|184,186|190,190|192,192|198,204|207,208|210,211|214,215|217,218|220,223|225,227|229,230|232,237|239,242|244,249|251,252|255,255|257,264|266,273|275,275|280,281|285,288|306,310|316,321|327,329|332,337|339,339|342,345|347,352|355,360|362,363|367,373|375,375|382,383|386,411|414,423|425,431|439,440|443,452|454,457|459,459|470,474|477,480|482,483|486,487|489,502 ??????????????-???????GGGT?EEEEEEEEEE?S?EEEEEBSSS?EE?SSS----??EEE?B??TTB?EEEEEE???TTTS??S??TTS?TTTEEEEEEEEEEEEEE?S?SB???EEEEEE?EEEE?S??SS??????S------???EEEEEB??EEEEEEEESS??EEEEEEE????SSS???T-T?-???EEEEEEE??TT?EE??SS?SB?HHHH?TTS?SS?HHHHTS?EEEE?HHHHHH?SS??S?SEEEEEEE?EEEEEEEE?S--??SS???GGGS???-------------?TTTTS?????EEEEEE?????TTT??SSSEEE?S??SSSS?SEEGGG??EEEEEE?SB???EEEEEES?S??----SS??GGGEEEEEEEEEEEEEEEEEEEEEEE??HHHHHHHHHH?THHHHHS???????TT??HHHHHHHHHH-HHTT?S??????????TTTTS??EEEE?TT??BS?GGGSHHHHHHHHHH??????????????-???????????????? 2R5J|A PF00501.23_AMP-binding_seed 354 929 !Q:5,7|10,10|12,12|16,20|23,26|29,41|44,44|63,64|66,66|68,69|71,71|73,77|80,81|83,84|88,90|107,107|112,115|117,122|125,125|127,131|142,148|150,151|155,157|159,166|168,180|183,183|189,203|206,211|217,224|231,231|234,282|284,287|291,293|298,299|301,302|304,305|308,311|314,314|322,322|326,329|336,349|352,358|360,362|364,367|370,370|373,374|376,383|390,392|394,394|405,433|438,439|444,444|446,449|454,456|459,462|466,466|468,473|476,480|491,491|494,500|503,503|505,505|509,549|552,570|572,579|582,631|633,634|636,642|644,645|649,651|663,663|665,669|671,672|677,677|679,680|686,686|688,701|703,704|706,708|711,731|734,734|737,741|743,745|748,755|757,757|765,767|770,770|772,772|774,783|786,790|793,795|798,798|801,804|807,810|812,817|820,827|829,833|835,835|838,842|847,847|850,855|857,857|860,880|884,884|886,886|896,896|898,901|903,904|906,906|908,913|922,922 Q:0,4|8,9|11,11|13,15|21,22|27,28|42,43|45,62|65,65|67,67|70,70|72,72|78,79|82,82|85,87|91,106|108,111|116,116|123,124|126,126|132,141|149,149|152,154|158,158|167,167|181,182|184,188|204,205|212,216|225,230|232,233|283,283|288,290|294,297|300,300|303,303|306,307|312,313|315,321|323,325|330,335|350,351|359,359|363,363|368,369|371,372|375,375|384,389|393,393|395,404|434,437|440,443|445,445|450,453|457,458|463,465|467,467|474,475|481,490|492,493|501,502|504,504|506,508|550,551|571,571|580,581|632,632|635,635|643,643|646,648|652,662|664,664|670,670|673,676|678,678|681,685|687,687|702,702|705,705|709,710|732,733|735,736|742,742|746,747|756,756|758,764|768,769|771,771|773,773|784,785|791,792|796,797|799,800|805,806|811,811|818,819|828,828|834,834|836,837|843,846|848,849|856,856|858,859|881,883|885,885|887,895|897,897|902,902|905,905|907,907|914,921|923,928 HHHHH---HH?T-TSE-----EE----ES-------------SS?EEEHHHHHHHHHHHHHHH--H-H--T-T?-?--TT?-E--EEE???SSHHHHHHHHHHHHTT?EEEE?--?T------TS?H-----HHHHHHHHHH-------T??EEE---E?-------S-------------TT?TTSTT?-----------???SE------EEESS-------?GGGGGS?SS????------------------------------------------???T----TSE---EEEE--E--E??SS----SS?EEEEEEH-HHH----HHHHSS?------------?SS??----?T---T?---EE-EE?-S?-------TTSTHH---H-HHHHHHHTTT?----------------------------EEEE??GGGT-T?---HHHH---HH----HHH-H------HT??---EEEEEHHHHH-HH-------HH-H?SHH-----------------------------------------HH-------------------T-?------SE--------------------------------------------------E--E-------E--ESS???HHHHHHHHHHH?T-----T?-EEEE-E??GGGSS?S--------------E--E---EE??----------------???SS?SS??-?-B---EE--?-----T-TEEEEEE--?TT-S?B?---?-----TT??---EE---EE-EE----ET----T--????BT--------T-?---H-HH-----HHHH-EE------E?TT---------------------STT?E-EEEEEEEEE-E-?--T--T-S----?-EEEEEEGG-GEEEET 3NYQ|A PF00502.14_Phycobilisome_seed 22 183 !Q:11,14|57,57|68,68|74,75|118,119|134,135|142,143|147,163|182,182 Q:0,10|15,56|58,67|69,73|76,117|120,133|136,141|144,146|164,181 HHHHHHHHTTT????HHHHHHHHHHHHTHHHHHHHHHHHHHTHHHHHHHHHHHHHHH?GGGTSTTSTT?SHHHH--HHHHHHHHHHHHHHHHHHHHTSTHHHHHHTTTTHHHHHHHHT??HHHHHHHHHHHHHH--HHHHHT??TTS??------------???HHHHHHHHHHHHHHHHHH? 3DBJ|A PF00503.15_G-alpha_seed 134 1005 !Q:0,144|152,152|171,198|201,201|230,232|234,361|383,508|521,522|531,532|538,559|565,581|588,595|602,607|609,626|632,666|676,697|708,709|711,711|718,718|723,723|725,758|760,760|774,774|783,820|836,836|841,847|857,857|869,871|876,876|879,908|910,912|918,918|931,931|933,933|935,935|938,962|967,978|980,981|984,986|994,996 Q:145,151|153,170|199,200|202,229|233,233|362,382|509,520|523,530|533,537|560,564|582,587|596,601|608,608|627,631|667,675|698,707|710,710|712,717|719,722|724,724|759,759|761,773|775,782|821,835|837,840|848,856|858,868|872,875|877,878|909,909|913,917|919,930|932,932|934,934|936,937|963,966|979,979|982,983|987,993|997,1004 ?????---------------------------------------------------------------------------------------???????????-?-??-?-?-?-?-?-??-?????-----------------?EEEEEEE?STTSSHHHHHHHHHHHHS????------------------------HH-HHHHTHHHHHHHHHHHHHHHHHHHHHTT???S--------------------------------------------------------------------------------------------------------------------------------STTHHHHHHHHHHHHHHHTTT?---------------------------------------------------------------------------------------------------------------------------??HHHHHHHHHHHH-?HHHHHHHT--TGGGS??-------------------?TTHHH-----------------HHTTHH--------HHTSSS--????H------------------HHHHH??-?----------------------------???SEEEEEEEE----------------------TTEEEEEEEE??S-TTTGGG-GGGS?T----------------------------------T?SEEEEEEEGGGTT?EETTEEEE--------------------------------------EHHHHHHHHHHHHHT?GGGT-------TSEEEEEEE?HHHHHHHHHHS?--GGGT?TT??----------------------------S?--SSHHH-HHHHHHHHHHTT?S?T-TT-----------------------??EEEE------------E??TT--?HHHHHHH---HHHHHHHH 3D7M|A PF00504.16_Chloroa_b-bind_seed 157 348 !Q:0,100|130,153|157,157|160,167|174,187|196,205|209,214|216,218|221,221|237,266|272,276|278,292|294,294|296,296|299,304|307,316 Q:101,129|154,156|158,159|168,173|188,195|206,208|215,215|219,220|222,236|267,271|277,277|293,293|295,295|297,298|305,306|317,347 ?????-??----??---?????--------???????---?-??---------????????????????????????????????????--??????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHS--------??--------------TTT-HH--------HHHHHS-------------?EEETTEEE???-------HHH------H---HH-HHHHHHHHHHHHHHS???---------------------------TTTTT???--G---------------G-G?TT----?-TT---------?STTTHHHHHHHHHHHHHHHHHHHHHHHHHHH 2WSE|1 PF00505.14_HMG_box_seed 31 71 !Q:0,5|22,22|25,28|44,44 Q:6,21|23,24|29,43|45,70 ??????SHHHHHHHHHHHHHHH?TT??--TTTHHHHHHHHHHTS?STTTHHHHHHHHHHHHHHHHHHHHHH 2YUK|A PF00506.13_Flu_NP_seed 3 552 !Q:0,36|61,62|86,112|115,116|121,122|126,126|131,132|135,136|146,146|153,158|178,180|189,190|192,193|197,198|200,200|202,203|214,215|228,233|245,247|266,267|281,281|284,285|303,313|318,319|326,329|331,333|346,354|358,359|362,363|365,368|382,382|386,386|397,400|404,408|411,412|416,417|421,421|425,429|433,436|438,438|440,443|445,448|451,452|454,457|459,465|467,467|478,479|483,485|500,503|506,510|514,515|521,521|524,525|527,527|529,529|531,533|537,537|539,539|542,551 Q:37,60|63,85|113,114|117,120|123,125|127,130|133,134|137,145|147,152|159,177|181,188|191,191|194,196|199,199|201,201|204,213|216,227|234,244|248,265|268,280|282,283|286,302|314,317|320,325|330,330|334,345|355,357|360,361|364,364|369,381|383,385|387,396|401,403|409,410|413,415|418,420|422,424|430,432|437,437|439,439|444,444|449,450|453,453|458,458|466,466|468,477|480,482|486,499|504,505|511,513|516,520|522,523|526,526|528,528|530,530|534,536|538,538|540,541 ?????????????????????????????????????HHHHHHHHHHHHHHHHHHHHHHHT??SHHHHSBHHHHHHHHHHHHHHTS???????????????????????????EE??EEEE??SSS?EEEE??EE??HHHHHHHHH-HHHGGG------HHHHHHHHHHHHHHHHHHH???HHHHHHTT??S??GGG??S?S??GGGHHHHTTS??HHHHHHHHHHHH------HHHHHSGGGTT---SSSHHHHHHHHHHHTTTS??SHHHHHHHHHHHH?SS??HHHHHHHHHHHHHHHHS???????????HHHH--TTHHHH????S???SSSHHHHHHHHH??------?EEE??SS??H----HHHHHHHHHHHHT?TTS?HHHHHHHHSS????TTT?????SS??TTS??TTB?EEE?????SEE????S?S????S????SS??B????S???????B?HHHHHHHHHS??SSS???HHHHHHHHHHHHHS----SS?????STT??BEETT?SS??S?B?S???SSS?S?SS?????????? 4DYB|A PF00507.14_Oxidored_q4_seed 99 147 !Q:9,22|26,32|35,45|47,49|54,54|57,57|60,61|64,75|103,107|115,116|122,124|134,134|142,142|144,147 Q:0,8|23,25|33,34|46,46|50,53|55,56|58,59|62,63|76,102|108,114|117,121|125,133|135,141|143,143 HHHHHHHHH--------------HHH-------SS-?----???-?H---HHHS?SS-SS??SS-????----???THHHHHHHHHHHHHHHHHHHHHHHHSS-----SSSHHHH--HHHHH---HHHHHHHHH-HHHHHHH?S???- 4HEA|A PF00508.12_PPV_E2_N_seed 82 219 !Q:0,2|14,16|24,27|53,53|61,63|93,95|100,100|105,105|112,112|124,132|149,150|155,155|159,159|166,166|173,173|187,187|191,198|202,203|211,218 Q:3,13|17,23|28,52|54,60|64,92|96,99|101,104|106,111|113,123|133,148|151,154|156,158|160,165|167,172|174,186|188,190|199,201|204,210 -??HHHHHHHHHHH---HHHHHHH????HHHHHHHHHHHHHHHHHHHHHHHTT?SEETTEE???HHHHHHHHHHHHHHHHHHHHHHTSTTTTS???TTTT?HHHH-TSSSTT?EEEEEEEEEEE??-??????EEEEEEEEEEEEETTE--EEEE?EEE?SSEEEE-EETTEE-EEEEEHHHHTTSS?SSS------??EEE--ETTEEEE??-????? 2NNU|A PF00509.13_Hemagglutinin_seed 15 576 !Q:0,2|6,7|9,11|14,15|18,18|25,25|29,29|32,35|37,37|39,40|43,47|50,51|54,54|58,58|66,66|72,75|77,77|84,84|87,87|91,91|94,94|120,120|123,123|125,125|130,138|143,143|148,149|151,152|158,158|160,160|162,167|170,173|180,181|185,185|195,195|207,207|210,212|217,217|220,220|225,233|236,237|239,241|244,244|254,254|257,257|266,266|278,279|281,284|288,288|290,291|293,293|295,297|306,310|314,315|317,317|319,320|324,325|328,328|330,330|332,333|337,337|339,339|341,353|363,365|369,370|372,372|377,379|384,386|389,389|411,414|417,423|426,426|485,485|489,489|495,497|508,575 Q:3,5|8,8|12,13|16,17|19,24|26,28|30,31|36,36|38,38|41,42|48,49|52,53|55,57|59,65|67,71|76,76|78,83|85,86|88,90|92,93|95,119|121,122|124,124|126,129|139,142|144,147|150,150|153,157|159,159|161,161|168,169|174,179|182,184|186,194|196,206|208,209|213,216|218,219|221,224|234,235|238,238|242,243|245,253|255,256|258,265|267,277|280,280|285,287|289,289|292,292|294,294|298,305|311,313|316,316|318,318|321,323|326,327|329,329|331,331|334,336|338,338|340,340|354,362|366,368|371,371|373,376|380,383|387,388|390,410|415,416|424,425|427,484|486,488|490,494|498,507 ???EEB??S???EE??SS?SSEEBS?EEE?EE????S?B??BT-----TB??EE?TTB?HHHHHHT?GGGTT????S?BSSEEE?SS?SBS?SS?EEETTHHHHHHHHHSBSEEEEEESS?GG-G?TTSB?-?----??BGGG?SSSS?-B??TTEEE?B?S------SS????EEEEEE??SSS?EEEEEEEEE?SSHHHHHHHHS?SS??-EEEE?SS?EEEE?????????BT--T---BS?EEEEEEEEE?TT?EEEEEESS?EEEESEEEEEE??S??-?EEE?S??B?S???SEEETTEE?????SEE?-S?S??EEE??EE?S?S??EEE?S?B??????----???TTSTBTTTB???BTT??S?SEEE???BTTB???EE?HHHHHHHHHHHHHHHHHHHHT????EE???????TT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGGEEE?SSS?EEESS???HHHHHHHHHT???????????--------------------------------------------------------- 2VIT|C PF00510.13_COX3_seed 21 261 !Q:2,8|32,36|65,68|104,105|114,114|117,123|153,153|183,183|186,186|225,227|230,231|260,260 Q:0,1|9,31|37,64|69,103|106,113|115,116|124,152|154,182|184,185|187,224|228,229|232,259 SS???????SHHHHHHHHHHHHHHHHHHHHHS??--?HHHHHHHHHHHHHHHHHHHHHHHHHTTT????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS??GGGTSSSS?TT?--????TTSHHHHHHHHHHHHHHHHHHHHHHHHTT-BHHHHHHHHHHHHHHHHHHHHHHHHHHHH?SS?TTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT???SS??HHHHHHHHHHHHHHHHHHHHHHHTTTTT? 1V55|C PF00511.12_PPV_E2_C_seed 99 85 !Q:7,7|19,19|26,28|31,33|35,35|38,42|46,48|50,51|57,57|71,73|83,84 Q:0,6|8,18|20,25|29,30|34,34|36,37|43,45|49,49|52,56|58,70|74,82 EEEEEES?HHHHHHHHHHH-HHTTTT-??EE???B?SS?----SSS??-S??EEEEE?SSHHHHHHHHHHS???TTSEEEEEE?? 1F9F|A PF00512.20_HisKA_seed 265 102 !Q:29,43|48,49|53,69|84,84 Q:0,28|44,47|50,52|70,83|85,101 HHHHHHHHHHHHHHHHHHHHHHHHHHHHH---------------TTTT??HHH-----------------HHHHHHHHHHHHHH-HHHHHHHHHHHHHHHTT 2C2A|A PF00514.18_Arm_seed 242 50 !Q:3,3|10,11|25,31|33,33 Q:0,2|4,9|12,24|32,32|34,49 HHH-HHHHHH--TTTHHHHHHHGGG------?S?HHHHHHHHHHHHHHTT 3IFQ|A PF00515.23_TPR_1_seed 555 34 !Q:15,15|30,30|33,33 Q:0,14|16,29|31,32 HHHHHHHHHHHHHTT?HHHHHHHHHHHHHH?TT? 3FP4|A PF00516.13_GP120_seed 24 606 !Q:0,15|17,20|23,25|28,30|43,45|47,48|52,52|55,56|59,60|64,66|88,88|90,97|100,100|102,123|126,158|161,161|168,170|175,177|184,211|213,214|216,216|219,219|223,225|228,234|236,237|239,240|243,243|249,250|253,254|259,259|269,269|271,271|273,276|284,287|291,291|295,296|301,307|311,311|326,326|328,332|334,335|340,341|347,347|349,350|352,357|359,361|367,367|390,397|401,429|431,432|450,451|456,462|466,494|500,500|503,504|515,520|523,527|541,545|549,555|562,563|565,565|581,605 Q:16,16|21,22|26,27|31,42|46,46|49,51|53,54|57,58|61,63|67,87|89,89|98,99|101,101|124,125|159,160|162,167|171,174|178,183|212,212|215,215|217,218|220,222|226,227|235,235|238,238|241,242|244,248|251,252|255,258|260,268|270,270|272,272|277,283|288,290|292,294|297,300|308,310|312,325|327,327|333,333|336,339|342,346|348,348|351,351|358,358|362,366|368,389|398,400|430,430|433,449|452,455|463,465|495,499|501,502|505,514|521,522|528,540|546,548|556,561|564,564|566,580 ????????????????S????EE???TT???HHHHHHHTSSEE???S??EEE?SS??EE??GGG--?HHHHHHHHHHHHGGGGTTTTT?B????????EE?S?-------------------??SS???----------------------------??SS?EEEEEE???SSTT???EEEEEE???????????????-----????????B??S?SS?EEB???SS???????B??B??TT?EEEEE??SS??SSSE-ESSEEEESB?S?B????BSSEEES????SSS?EEE-?TTTT------?TTS?EEEEEEEEEEEEEE?S?????S-?EEEE--TTEEE?S??S???---S???EEEEE?HHHHHHHHHHHHHHHHHHTTSS------??EEE?-???------------------------S??HHHHTEEEEETTEEEEE??GGGT?------EEE???????--------?????-???---??EEEEE?EE??EEETTTTEEE??????SS---??EEEEEEEEEEEEE--???STT?-----?SEEEEE??S?THHHHHHHHTTEEEE??????????????????------- 1RZJ|G PF00517.12_GP41_seed 23 244 !Q:0,11|46,49|67,69|72,73|77,78|80,88|90,92|95,99|102,103|110,111|146,243 Q:12,45|50,66|70,71|74,76|79,79|89,89|93,94|100,101|104,109|112,145 ---------???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH----HHHHHHHHHHHHHHHHH???SS??SSS--S?????????S???SS-----HH--HHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?------------------------------------------------------------------------------------------------- 3H01|A PF00518.12_E6_seed 26 112 !Q:4,5|7,8|20,20|22,22|28,28|33,34|55,55|66,66|71,72|78,79|81,82|94,95|101,101|107,108 Q:0,3|6,6|9,19|21,21|23,27|29,32|35,54|56,65|67,70|73,77|80,80|83,93|96,100|102,106|109,111 BTTT??B??HHHHHHHHHTT?B?EEETT-EEEB??HHHHHHHHHHHHHHHEEEEE?HHHHHHHHTS?GGGS??EETTT??B??HHHHHHHHHTT??EEEET-TEEEE??HHH 4GIZ|C PF00519.12_PPV_E1_C_seed 66 450 !Q:0,152|165,166|182,182|191,191|217,217|229,233|236,237|250,251|266,268|271,271|278,278|297,297|301,301|317,317|319,319|326,326|344,345|348,350|353,356|359,362|370,370|374,374|389,406|423,449 Q:153,164|167,181|183,190|192,216|218,228|234,235|238,249|252,265|269,270|272,277|279,296|298,300|302,316|318,318|320,325|327,343|346,347|351,352|357,358|363,369|371,373|375,388|407,422 ----------------------------------------------------------------------------------------------------------------------------?---------------????--???????HHHHHHHHHHTT??SHHHHHHHHHHTTTT?HHHHHHTT?TTHHHHHHHHHHHHHHHHHHHHHHS?HHHHHHHHHHH?-?--SS??THHHHHHHHHTT??HHHHHHHHHHHHHT--?TT?SEEEEE?SSSSSHHHHHHHHHHHHT?EEE?GGGTTSGGGGGGGTT?S?EEEEEE?HHHHHHHHHTTTGGGGT??EE???SS????EE????EEEEESS?STT?GGGGGGTTTEEEEE?????-????????????HHHHHHHHHHSTTTTT???-???????--?----????????? 1R9W|A PF00520.26_Ion_trans_seed 285 413 !Q:20,20|22,22|24,44|73,75|79,119|124,129|141,143|145,147|157,161|163,163|166,170|210,325|328,328|330,330|347,349|353,385|394,394 Q:0,19|21,21|23,23|45,72|76,78|120,123|130,140|144,144|148,156|162,162|164,165|171,209|326,327|329,329|331,346|350,352|386,393|395,412 HHHHHHHHHHHHHHHHHHTT?S?S---------------------STTTTSHHHHHHHHTTHHHHHHHHHHHT?-?SHH-----------------------------------------HHHH------HHHHHHHHHHH---G---GGGGGGGGG-----S?HH-----HHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHT-------------------------------------------------------------------------------------------------------------------?TT?S?SSHHHHHHHHHHHHTT???SSS???------------------------------SHHHHHHH-HHHHHHHHHHHHTTHHHH 2KYH|A PF00521.15_DNA_topoisoIV_seed 110 605 !Q:0,0|3,3|8,10|21,21|24,24|27,28|32,32|44,45|50,51|66,67|71,73|76,76|83,86|88,88|91,96|100,100|105,105|111,111|120,120|122,122|126,126|137,139|142,142|148,148|161,164|177,177|179,180|183,184|189,192|195,195|197,198|200,200|202,204|207,207|211,218|220,221|232,234|236,237|242,243|246,246|253,259|263,265|273,274|277,278|285,285|292,295|299,303|306,307|310,311|316,318|321,321|324,325|330,331|333,333|335,337|340,343|351,352|367,367|374,374|376,378|382,384|417,424|434,443|456,456|459,463|470,470|478,479|481,548|556,556|558,558|591,591 Q:1,2|4,7|11,20|22,23|25,26|29,31|33,43|46,49|52,65|68,70|74,75|77,82|87,87|89,90|97,99|101,104|106,110|112,119|121,121|123,125|127,136|140,141|143,147|149,160|165,176|178,178|181,182|185,188|193,194|196,196|199,199|201,201|205,206|208,210|219,219|222,231|235,235|238,241|244,245|247,252|260,262|266,272|275,276|279,284|286,291|296,298|304,305|308,309|312,315|319,320|322,323|326,329|332,332|334,334|338,339|344,350|353,366|368,373|375,375|379,381|385,416|425,433|444,455|457,458|464,469|471,477|480,480|549,555|557,557|559,590|592,604 ?SS?BTTT???HHHHHHHHHH-HH-TT??SSS?BEEHHHHHHHH--HHHT??SHHHHHHHHHHHTT?-TTT?--TT?SEEEES????T-TS???-??TTS?EEEE?TTHHH-HHTTSTTS?S?EEE?TTSSSEEESS???SS?HHHHH?EEEEETTEEEEE????HHHHHHHHHHHH-H-?TT??HHHH----HT-T--S?S???SS?EEE?------?H--HHHHHHHHHS---E--EEEE--EE?EEEEEE?------TTS--?EEEEEEE??TT??HHHHHH-HHHHHH----HTT-----SS??EE--EEEE?-?BT-TB??EEEE--E?T---TS?---HHHHHHH--HHHHSSSEEEEEEE?EEESSS-S---EEE?-?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--------HHHHHHHHH----------HTHHHHHHHHHT?SS-----HHHHHH-HHHHHHT??H--------------------------------------------------------------------HHHHHHH-T?BGGGGSHHHHHHHHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHH 3IFZ|A PF00522.13_VPR_seed 12 100 !Q:0,4|7,15|36,38|55,55|59,63|85,93|95,96|99,99 Q:5,6|16,35|39,54|56,58|64,84|94,94|97,98 ?????SS---??????STTTHHHHHHHHHHHHHHHH???SHHHHHHHHHHHHTSS?HHH-----HHHHHHHHHHHHHHHHHHHHH---------S??SS? 1DSK|A PF00523.13_Fusion_gly_seed 12 517 !Q:0,2|33,33|35,38|40,46|48,48|50,52|79,80|84,91|93,93|96,98|100,103|107,109|115,116|147,148|165,165|175,176|180,180|198,200|209,212|215,215|218,218|221,221|223,223|243,244|248,248|257,258|295,296|301,303|310,312|325,327|330,330|334,334|340,340|343,345|348,349|356,358|362,362|366,367|371,374|389,389|392,392|395,395|402,403|406,408|411,411|417,417|421,421|433,449|454,457|461,461|496,496 Q:3,32|34,34|39,39|47,47|49,49|53,78|81,83|92,92|94,95|99,99|104,106|110,114|117,146|149,164|166,174|177,179|181,197|201,208|213,214|216,217|219,220|222,222|224,242|245,247|249,256|259,294|297,300|304,309|313,324|328,329|331,333|335,339|341,342|346,347|350,355|359,361|363,365|368,370|375,388|390,391|393,394|396,401|404,405|409,410|412,416|418,420|422,432|450,453|458,460|462,495|497,516 ???GGGGTTTEEEEEEEEEEEEEEEEEEEEEEE?S????S------?B?S???HHHHHHHHHHHHHHHHHHHHHHHHHH--HHS--------S?SS???S????GGG---GSEEE--HHHHHHHHHHHHTHHHHHHHHTTHHHHHHS??SEEEEEETTEEEEEEE?TTHHHHHHH??SSB?TTTHHHHHHHHHHHHHH---HHHHHHTT????SS?GG-GS?B?HHHHHHHHGGGHHHHHHHH??SSS?HHHHHHSS??EEEEEEEETTTTEEEEEEEEEEEEEEEEEEEEEEEE??EEET---TEEEEE???SEEEEETTEEEE???TT-SEE?SSEEE?SS???EE??HHHHHH---HTT?GGG??EEE????GGGSEEEETTEEEE?TT-TS?EEESSS??EE???TT?SSEEE?TTT?SEEEETTEEEE???-?????????????GGGB????HHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHTTTT 3KPE|A PF00525.13_Crystallin_seed 11 70 !Q:0,2|5,6|16,16|18,20|30,31|35,39|41,49|54,55|57,58|60,61 Q:3,4|7,15|17,17|21,29|32,34|40,40|50,53|56,56|59,59|62,69 ???EE??GGGGGGGSS-S???HHHHTTTSB??STT?????S?--------TTSS??B??S--HHHHHHHH 2YGD|A PF00527.13_E7_seed 75 148 !Q:0,55|57,96|106,106|109,110|112,113|121,122|126,126|136,136|139,140|142,143 Q:56,56|97,105|107,108|111,111|114,120|123,125|127,135|137,138|141,141|144,147 ?---------?------------??-----------------------------??S----------------------------------------SEEEEEEEB-TT--T??EEEEEEE??HHH-HHHHHHHHH-HT??B??HHHH 2EWL|A PF00528.17_BPD_transp_1_seed 81 289 !Q:14,15|31,35|38,38|42,48|53,58|69,107|111,113|117,117|119,120|142,142|145,145|157,158|187,187|199,210|224,225|227,258|287,288 Q:0,13|16,30|36,37|39,41|49,52|59,68|108,110|114,116|118,118|121,141|143,144|146,156|159,186|188,198|211,223|226,226|259,286 HHHHHHHHHHTSTT??HHHHHHHHHHHHHHH-----HS?HHH-------HHHH------THHHHHHHHS--------------------------------------?SSS---HHH-H--HHHHTTTSHHHHHHHHHHHHH-TS?HHHHHHHHHHT??HHHHHHHTHHHHHHHHHHHHHHHHHHHH-HHHHHHHTTTT----------??SHHHHHHHHHHSS??H--------------------------------HHHHHHHHHHHHHHHHHHHHHHHHHHHT?? 3PUW|F PF00529.15_HlyD_seed 44 360 !Q:4,5|8,8|14,15|17,17|20,20|23,23|26,26|32,33|42,46|58,60|63,69|82,97|112,123|141,141|145,159|163,165|168,168|171,171|174,174|176,181|183,183|186,186|193,193|203,203|218,218|220,220|228,228|233,233|237,242|252,252|254,255|271,272|276,278|281,281|286,287|289,359 Q:0,3|6,7|9,13|16,16|18,19|21,22|24,25|27,31|34,41|47,57|61,62|70,81|98,111|124,140|142,144|160,162|166,167|169,170|172,173|175,175|182,182|184,185|187,192|194,202|204,217|219,219|221,227|229,232|234,236|243,251|253,253|256,270|273,275|279,280|282,285|288,288 EEEE??SS?EEEEE??S?TT?EE?TT?EEEEE??HHHHHHHH-----HHHHHHHHHHH---HH-------HHHHHHHHTTSS---------------?HHHHHHHHHHHHHH------------HHHHHHHHHHHHTTEEE?SSS---------------EEE???SS?BT?EE?T------T?SS?SEEEEE?SSEEEEEEE?HHHHHHHHHHHHTT?S?EEETTEE?EEEE?TTS-----?EEEEEEEEB?S??EEETTTTEEEEEEEE??GGG???TT?EEEE--E?????????--?--?????????????????????????????????????--?????????????????? 2F1M|A PF00530.13_SRCR_seed 136 191 !Q:2,2|6,7|15,15|17,22|24,25|27,27|29,37|44,44|46,46|48,56|59,60|69,70|73,82|84,84|90,90|95,109|111,115|118,119|121,121|123,128|130,137|139,141|148,154|156,158|160,160|163,173|175,175|177,178|181,185|190,190 Q:0,1|3,5|8,14|16,16|23,23|26,26|28,28|38,43|45,45|47,47|57,58|61,68|71,72|83,83|85,89|91,94|110,110|116,117|120,120|122,122|129,129|138,138|142,147|155,155|159,159|161,162|174,174|176,176|179,180|186,189 ES?SST--TEEEEEE-E------E--T-T---------EEEEEB?T-T-------??HH--HHHHHHHH--TT--------?-S?EEEEE?TTTT----------???-?S?----EE--E?S-----?B------??S-??SSGGGS-------B?--S?TT?--??---?-?G-G--GB----?EEEE? 2OY3|A PF00531.17_Death_seed 88 98 !Q:7,8|12,12|21,21|25,27|29,30|40,42|44,44|46,46|48,48|64,66|71,71|85,85|92,92 Q:0,6|9,11|13,20|22,24|28,28|31,39|43,43|45,45|47,47|49,63|67,70|72,84|86,91|93,97 HHHHHHH--HHT?SSSHHHHH-HHH---H??HHHHHHHHH---H?T-T?HHHHHHHHHHHHHHH---HGGG?SHHHHHHHHHHTT?HHHHHH-HHHHH 1FAD|A PF00532.16_Peripla_BP_1_seed 6 329 !Q:0,0|9,9|11,12|17,20|44,45|52,54|65,66|72,73|75,75|91,91|99,100|102,102|106,106|108,108|112,112|117,118|125,125|140,141|152,152|174,177|186,186|205,207|210,210|217,217|235,238|259,264|267,268|276,277|282,285|300,304|310,312|317,321 Q:1,8|10,10|13,16|21,43|46,51|55,64|67,71|74,74|76,90|92,98|101,101|103,105|107,107|109,111|113,116|119,124|126,139|142,151|153,173|178,185|187,204|208,209|211,216|218,234|239,258|265,266|269,275|278,281|286,299|305,309|313,316|322,328 ?EEEEEEES?T--TSHH----HHHHHHHHHHHHHHHTEEEEEEE??SHHHHH---HHHHHHHHHT??EEEEE-?S?GGGHHHHHHHHHHTT?EEEEESS??B?TTS?B?TTS?EEEE?-HHHHHH-HHHHHHHHHHHHHT??GGGEEEEEEE?TTSHHHHHHHHHHHHHHHHTT?--?GGGEEEEE?SSSSHHHHHHHHHHHHTT?--TT?SEEEEE?SSHHHHHHHHHHHHHTT--??GGGEEEEEESSGGGHHHHTS------SS??SEEEEEE??HHHH----HHHHHHHHHHHHHH?????SEEEE???EEEE-----TTTHHHH 1BYK|A PF00533.21_BRCT_seed 114 149 !Q:2,3|8,8|13,20|22,23|31,33|42,42|45,70|73,74|78,79|83,87|91,111|115,127|136,136|140,140 Q:0,1|4,7|9,12|21,21|24,30|34,41|43,44|71,72|75,77|80,82|88,90|112,114|128,135|137,139|141,148 GB??TTTT?EEEE-------?S??HHHHHHH---HHHHHHTT?EE-------------------------?SS??TTT??EEE----?SSS--------------------?SHH-------------HHHHHHTT?EEE?HHHHHHHH 3PC8|A PF00534.15_Glycos_transf_1_seed 63 234 !Q:0,1|10,15|21,24|27,27|42,50|54,55|61,73|88,88|93,95|98,98|100,103|111,115|121,122|124,145|147,148|159,160|165,167|174,175|179,186|192,192|195,198|212,212|214,220 Q:2,9|16,20|25,26|28,41|51,53|56,60|74,87|89,92|96,97|99,99|104,110|116,120|123,123|146,146|149,158|161,164|168,173|176,178|187,191|193,194|199,211|213,213|221,233 ??HHHHHHTT??????EEEEE????GG-GTHHHHHHHHHHHH---------HSS??EEEEE?----------??TTHHHHHHHHHTTT?GGGB???BS?S---?THHHHHT----?SEEEE??S?--------------------?S??HHHHHHHHTT??EEEE?-?TTSTTT??BTT--------TEEEE?TT---?HHHHHHHHHHHHH?H-------HHHHHHHHHHHHH 3RSZ|A PF00535.21_Glycos_transf_2_seed 253 247 !Q:8,15|31,54|66,66|68,70|74,75|86,92|96,96|102,102|105,109|121,123|126,129|141,141|144,145|156,156|169,169|173,174|177,179|185,191|194,195|198,207|213,214|224,224|228,228|231,231|234,235|247,247 Q:0,7|16,30|55,65|67,67|71,73|76,85|93,95|97,101|103,104|110,120|124,125|130,140|142,143|146,155|157,168|170,172|175,176|180,184|192,193|196,197|208,212|215,223|225,227|229,230|232,233|236,246 EEEEEESS?------?HHHHHHHHHHHHHSS-----------------------?GGGEEEEEEEE?S???GGG--THHHHHHHHS-------SSS?EEEEE?SS??--?HHHHHHHHHHH-??SS----EEEEEESSEEE?TT-?HHHHHHHHHH?TTEEEEEEEEEE?SSS??EE???TTEEE-------EE?-TT?--------?EEEEE??HHHHHHTTT?TTS?EE?SB??SSSEEEEHHHH- 3F1Y|A PF00536.25_SAM_1_seed 65 76 !Q:0,1|4,4|14,16|18,18|20,24|36,36|45,46|50,51|55,55|58,59 Q:2,3|5,13|17,17|19,19|25,35|37,44|47,49|52,54|56,57|60,75 ??TT?SSHHHHHHH---T-T?----GGGHHHHHHHT?SSTTGGGG??HHH--HHH-HT??STTHHHHHHHHHHHHH 1B0X|A PF00537.13_Toxin_3_seed 33 74 !Q:2,6|9,13|18,27|29,32|43,43|46,46|50,50|55,55|57,58|61,61|70,70 Q:0,1|7,8|14,17|28,28|33,42|44,45|47,49|51,54|56,56|59,60|62,69|71,73 EE-----EE--??-SSSS?????-----S-?--HHHHHHHHHH-HT?SEE-EEEE?S--TT?EEEEEEEE?SSS 1JXC|A PF00538.14_Linker_histone_seed 20 83 !Q:0,3|15,17|20,20|33,33|36,39|43,45|66,71|74,76|81,82 Q:4,14|18,19|21,32|34,35|40,42|46,65|72,73|77,80 ????HHHHHHHHHHT???SS?EEHHHHHHHHHH-HS-???TTH---HHHHHHHHHHHHHTTSEEEE?----?SS???EEEE?? 1HST|A PF00539.13_Tat_seed 83 77 !Q:0,5|9,10|13,13|16,20|24,24|26,27|33,34|37,39|41,51|53,53|58,58|61,68|70,70 Q:6,8|11,12|14,15|21,23|25,25|28,32|35,36|40,40|52,52|54,57|59,60|69,69|71,76 ?-----TTS??SS?TT?????TTT?S?-TTSSS??SS???S-----??????S?SSSS?SS?????-??S?SSHHHH 1TIV|A PF00540.13_Gag_p17_seed 3 142 !Q:0,0|2,2|20,20|24,24|27,28|47,47|51,51|69,69|89,92|111,122|126,141 Q:1,1|3,19|21,23|25,26|29,46|48,50|52,68|70,88|93,110|123,125 ?S?TTSSSSHHHHHHHHSEE?SSS?EE??HHHHHHHHHHHHHHHSSS?TTT?HHHHHHHHHHHHHHTTT?HHHHHHHHHHHHHHHHHHH????SBHHHHHHHHHHHHGGGG??---------?SSS????--?????????? 2K4I|A PF00541.12_Adeno_knob_seed 46 280 !Q:3,3|6,8|10,10|12,12|14,16|21,21|31,31|45,46|48,50|55,55|60,65|74,74|78,78|80,80|82,89|94,94|98,98|101,133|140,142|145,146|148,149|152,178|182,182|187,200|203,204|218,221|238,240|243,245|255,256|259,261|263,265|267,267|269,270|272,274 Q:0,2|4,5|9,9|11,11|13,13|17,20|22,30|32,44|47,47|51,54|56,59|66,73|75,77|79,79|81,81|90,93|95,97|99,100|134,139|143,144|147,147|150,151|179,181|183,186|201,202|205,217|222,237|241,242|246,254|257,258|262,262|266,266|268,268|271,271|275,279 EES?SS?-?S?B?S---SSTT?EEEEEEEEE-ETTEEEEEEEEEE?-S??-TGGG?SSSS------EEEEEEEE?TTS?B?S--------SSSB?STT?EE---------------------------------EETTEE?--SS??S??GG---------------------------GSB?TTTS??-----------?SS??GGGEEEEEEEGGG?---TTSEEEEEEEESGGGS???TT???SEEEEEEEE??TT?-?T---T-S??B???EEEEE 3O8E|A PF00542.14_Ribosomal_L12_seed 191 85 !Q:8,10|13,13|22,25|28,28|31,34|46,48|53,53|59,60|62,62|78,79|84,84 Q:0,7|11,12|14,21|26,27|29,30|35,45|49,52|54,58|61,61|63,77|80,83 SEEEEEEE?--TT?HHHHHHHH----HH-HH-???HHHHHHHHTTT---TSTT?EEEEE--E?HHHHHHHHHHHHHTT?-EEEE? 2ZJQ|5 PF00543.17_P-II_seed 93 134 !Q:5,7|23,27|35,76|87,88|104,105|108,110|113,114|121,121|123,124|130,130|133,133 Q:0,4|8,22|28,34|77,86|89,103|106,107|111,112|115,120|122,122|125,129|131,132 EEEEE?--GGGHHHHHHHHHHTT-????EEEEEEE???????-???????--------------------?????-?EEEEEEEEEE-?GGGHHHHHHHHHHHH??SS---TT??EEEEEE?S--EEEET-TT? 4AFF|A PF00544.14_Pec_lyase_C_seed 10 251 !Q:2,2|8,8|17,20|33,34|42,45|48,49|54,54|65,65|73,73|77,87|90,90|100,103|109,109|112,112|120,120|124,124|128,128|132,133|140,145|150,150|153,153|161,161|169,169|174,176|179,179|186,187|194,194|197,197|203,203|206,206|211,211|218,218|226,226|230,233|238,238|241,241|248,248 Q:0,1|3,7|9,16|21,32|35,41|46,47|50,53|55,64|66,72|74,76|88,89|91,99|104,108|110,111|113,119|121,123|125,127|129,131|134,139|146,149|151,152|154,160|162,168|170,173|177,178|180,185|188,193|195,196|198,202|204,205|207,210|212,217|219,225|227,229|234,237|239,240|242,247|249,250 TS?EEEEE?SEEETTTT????SHHHHHHHSEEE??SSEEEEE---?TT??EEES-SEEEEEGGGT?EEEEEES?EEE?-------???SS?EEETTTEEE????SEEEE-TT?EEEEEES?EEE?TTS?GGG??EETTEE??????SEEE?TT?EEEEEES?EEEEEEE?EEES?-?TT?HHHHTT??EEEEES?EE-EEEEE?SS-EESS?EEEEES?EEEEETT?SSS????SEEE?TT?EEEEES?EE 1PXZ|A PF00545.15_Ribonuclease_seed 80 147 !Q:1,1|6,9|19,33|36,36|41,41|43,45|48,71|73,76|79,82|84,84|89,92|94,97|99,102|105,106|108,110|115,115|118,120|122,128|130,131|138,138|142,143|147,147 Q:0,0|2,5|10,18|34,35|37,40|42,42|46,47|72,72|77,78|83,83|85,88|93,93|98,98|103,104|107,107|111,114|116,117|121,121|129,129|132,137|139,141|144,146 S?HHHH----HHHHHHHHT???------------SS-TTTT?B???TT?----------------------?S????TT----S?EEEE???-T----T?---SS??S--?EEEE?SS---T-------T?-EEEESS-TTS??EEE- 5RNT|A PF00547.13_Urease_gamma_seed 85 112 !Q:0,3|11,11|28,29|31,31|47,47|52,64|76,77|82,82|89,89|110,111 Q:4,10|12,27|30,30|32,46|48,51|65,75|78,81|83,88|90,109 ????HHHHHHH-HHHHHHHHHHHHHHTT??B?HHHHHHHHHHHHHHH-HHHT-?----------?HHHHHHHGGGS??GGGB?TTHHHH?SEEEEEEEETTEEEEEEEES?? 1FWI|A PF00548.15_Peptidase_C3_seed 20 210 !Q:6,9|24,34|43,44|53,57|62,63|65,67|82,85|90,90|92,92|95,96|106,107|109,112|115,115|117,120|125,127|130,133|142,142|163,163|177,181|184,184|187,187|192,195|206,206|208,208 Q:0,5|10,23|35,42|45,52|58,61|64,64|68,81|86,89|91,91|93,94|97,105|108,108|113,114|116,116|121,124|128,129|134,141|143,162|164,176|182,183|185,186|188,191|196,205|207,207|209,209 HHHHHH----HHHHHHHHEEEEEE-----------TTEEEEEE--EEEBTEEE-----EEGG--G???SEEEETTEEEEEEE----EEEE-E?TT??EEEEEEEEE--E?---SS?B-???GGGB?--SS??-?EEEEEEEE?SSSSTTEEEEEEEEEEEEEE-EETTEEEEEEEEE?????TT?TT?EEEE----TTEEEEEEEE-E?S 3ZVG|A PF00549.14_Ligase_CoA_seed 20 167 !Q:3,3|20,31|57,58|62,63|76,76|78,78|89,89|94,94|96,96|110,110|114,114|118,119|128,128|132,133|136,136|139,139|150,150|153,153 Q:0,2|4,19|32,56|59,61|64,75|77,77|79,88|90,93|95,95|97,109|111,113|115,117|120,127|129,131|134,135|137,138|140,149|151,152|154,166 EES?HHHHHHHHHHHHHHTT?????-----??GGGEEEEETTEEEEETTSHHHHTTS??TTT??HHHHHHHHHGGG?T-TEEEEEEEEE?STTS?S?HHHHHHHHHHHHH-HTS?TTS??EEEEEEES?TTS--TT?HH-HHHHHHHHTT?EE?SSHHHHHHHHHHH 2FPP|A PF00550.20_PP-binding_seed 163 98 !Q:5,5|12,20|22,22|25,29|32,33|36,39|41,41|45,48|63,63|65,68|70,76|79,80|84,84|86,88 Q:0,4|6,11|21,21|23,24|30,31|34,35|40,40|42,44|49,62|64,64|69,69|77,78|81,83|85,85|89,97 HHHHH-HHHHHH--?----??G-GG?---?TT-?BT----T-TTT??-?HHHHHHHHHHHHHH-H----T-?--???HH--HHH-T-??BHHHHHHHH 2XZ0|D PF00551.14_Formyl_trans_N_seed 15 221 !Q:0,0|9,11|18,18|29,31|41,41|44,44|55,55|60,61|65,83|88,88|103,104|112,113|115,117|122,122|135,135|139,148|150,159|162,168|175,177|182,182|184,184|191,194|196,196|198,199|213,213 Q:1,8|12,17|19,28|32,40|42,43|45,54|56,59|62,64|84,87|89,102|105,111|114,114|118,121|123,134|136,138|149,149|160,161|169,174|178,181|183,183|185,190|195,195|197,197|200,212|214,220 ?EEEEEESS??-HHHHHH-HHHHHTTSSS---SEEEEEEES?TT?HHHHHHHHHT?EEEE??GGG-------------------SSSH-HHHHHHHHHHHGGG??SEEEESS??S???HHHH-HHTTTSEEEEES?SSS??-----??-S??????????SS?-----?EEEEEE??-SSTT?S?EEEEEE????S-S??HHHHHHHHHHHHH-HHHHHHH 1Z7E|A PF00552.16_IN_DBD_C_seed 37 62 !Q:0,1|9,12|15,15|39,41|48,53|61,61 Q:2,8|13,14|16,38|42,47|54,60 ??SEEEEEE---?SS?SSEEEEEEEEEESSSEEEEESSS?--EEEEEG------GGEEEEE? 1IHV|A PF00553.14_CBM_2_seed 17 108 !Q:4,5|8,8|10,10|13,13|23,23|27,27|37,38|41,42|64,64|71,71|73,77|81,82|89,90|93,94|96,96|106,106 Q:0,3|6,7|9,9|11,12|14,22|24,26|28,36|39,40|43,63|65,70|72,72|78,80|83,88|91,92|95,95|97,105|107,107 EEEE??EE-E?SS?EEEEEEEEE?SSS?EESEEEEEE?-SS??EEEEEESSEEEEETTEEEEEE?SSTTEE?S-----SEE??EEEEEE??SS??S?SEEEETTEE-E 2CZN|A PF00554.17_RHD_seed 21 221 !Q:5,5|7,8|12,13|15,15|19,20|22,22|24,27|29,29|32,32|37,40|47,48|50,50|54,54|61,62|66,68|70,70|72,75|82,84|86,86|91,96|103,103|106,108|110,110|113,114|120,122|144,144|149,149|152,156|160,160|162,166|184,185|195,195|198,200|204,204|206,206|209,211 Q:0,4|6,6|9,11|14,14|16,18|21,21|23,23|28,28|30,31|33,36|41,46|49,49|51,53|55,60|63,65|69,69|71,71|76,81|85,85|87,90|97,102|104,105|109,109|111,112|115,119|123,143|145,148|150,151|157,159|161,161|167,183|186,194|196,197|201,203|205,205|207,208|212,220 EEESS?B??SSB??B?GGG-?S?S????B-TT?BTTB????EEEEES??S-SEE-EEEEEE??SSS-??B?S----SEEEET---T-EETT------EEEEEE?SS-??E-EE??SEEEE???TTTHHHHHHHHHHHHHHSSSS?TTSS?SS?????SSS?S?????HHHHHHHHHHHHHHHHH??TTEEEEEEE?EE-??TTS?S?EE???EEEEEEEBT 1S9K|C PF00555.14_Endotoxin_M_seed 36 261 !Q:2,6|10,14|16,16|18,33|36,36|38,42|50,50|52,53|55,57|71,72|78,80|97,102|105,107|110,114|117,118|123,126|129,129|131,134|150,155|183,185|188,190|193,193|202,203|205,205|209,217|222,223|234,234|238,239|241,248|259,260 Q:0,1|7,9|15,15|17,17|34,35|37,37|43,49|51,51|54,54|58,70|73,77|81,96|103,104|108,109|115,116|119,122|127,128|130,130|135,149|156,182|186,187|191,192|194,201|204,204|206,208|218,221|224,233|235,237|240,240|249,258 EE?????EEE?????S?S--------------??TT?S---??HHHHHTT-S??S???EEEEEEEEEEEEE??TTSTT?--EEEEEEEEEEEEESTT?--???EE???EE???--SS??EEEE---?TT?E----EEEEEEEEEEEEETT------EEEEEEEEEEEEEEETTTTEEEEEEEE?--SS???EE-EEEGGGTS??S?SSS--------?HHHH??EEEEEEEEEE?GGG??E--------EEEEEEEETT?? 4ARX|A PF00556.15_LHC_seed 28 43 !Q:0,0|35,35 Q:1,34|36,42 ?GGGGGTSSHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHH 1NKZ|A PF00557.19_Peptidase_M24_seed 656 871 !Q:15,15|18,21|23,24|26,29|31,37|39,65|67,101|103,104|114,116|118,122|125,127|130,136|138,139|141,152|156,165|168,177|187,189|191,200|203,206|208,220|222,222|224,245|247,250|252,285|287,288|294,294|299,302|306,307|313,316|318,319|321,327|329,342|344,345|347,350|352,357|361,361|364,370|378,380|382,389|393,393|395,395|397,403|405,405|407,423|425,426|440,441|443,449|451,456|458,466|468,494|497,498|500,507|510,510|512,519|521,521|523,528|530,530|534,537|539,567|570,575|577,588|590,594|596,651|654,661|663,678|681,681|686,705|709,718|720,720|722,774|777,850|852,852|856,856|859,864|869,869 Q:0,14|16,17|22,22|25,25|30,30|38,38|66,66|102,102|105,113|117,117|123,124|128,129|137,137|140,140|153,155|166,167|178,186|190,190|201,202|207,207|221,221|223,223|246,246|251,251|286,286|289,293|295,298|303,305|308,312|317,317|320,320|328,328|343,343|346,346|351,351|358,360|362,363|371,377|381,381|390,392|394,394|396,396|404,404|406,406|424,424|427,439|442,442|450,450|457,457|467,467|495,496|499,499|508,509|511,511|520,520|522,522|529,529|531,533|538,538|568,569|576,576|589,589|595,595|652,653|662,662|679,680|682,685|706,708|719,719|721,721|775,776|851,851|853,855|857,858|865,868|870,870 HHHHHHHHHHHHHHH-HH----H--H----H--??---T---------------------------T-------------------------?---------B--HHHHHHHHH---H-----HH---HH-------T--T-----------?SEE----------SS-----?---?EEEEGGGGG---S----------TT?---B?----------?-S?B----------------?----?T----T---------------------------------?E--EEEEE?EEET----TEE??EEEEE----E--S-------S--------------S??H----H------HHH-HH-------HHHHHHH---H--------HHH-H-H?-?----T-T-----?-----------B--HHHHHHHHHHHHH--H-------T------T-?-------G---------------------------GG??S-------?SE-E--------E?S------S-SSS----E-----------------------------EE------E------------E-----S--------------------------------------------------------TT-----???B---------??-----TT?EEEE-??-----------------EEE----------E-T-----------------------------------------------------TT--------------------------------------------------------------------------E-EEE?BE------EEEE?S 2MAT|A PF00558.14_Vpu_seed 16 101 !Q:0,51|64,64|77,77|79,79|82,88|92,92|99,100 Q:52,63|65,76|78,78|80,81|89,91|93,98 ----------------------?----------------------?------HHHHHHHHHHTT?HHHHTTTTHHHH-T?SS??-----GGG?SHHHHT?? 2JPX|A PF00560.28_LRR_1_seed 2414 45 !Q:1,2|6,7|9,10|12,15|18,36|39,40|44,45 Q:0,0|3,5|8,8|11,11|16,17|37,38|41,43 T??EEE??S--S--??EE?----------------??GG--GGG?- 2A0Z|A PF00561.15_Abhydrolase_1_seed 48 473 !Q:0,0|7,7|14,62|64,64|83,83|87,87|89,95|115,115|118,121|128,128|132,138|142,213|220,220|222,222|224,245|261,271|287,288|292,296|304,311|318,318|321,324|328,328|332,334|341,344|356,365|384,393|395,395|404,404|406,408|411,411|418,418|426,435|443,445|447,447|449,456|465,466 Q:1,6|8,13|63,63|65,82|84,86|88,88|96,114|116,117|122,127|129,131|139,141|214,219|221,221|223,223|246,260|272,286|289,291|297,303|312,317|319,320|325,327|329,331|335,340|345,355|366,383|394,394|396,403|405,405|409,410|412,417|419,425|436,442|446,446|448,448|457,464|467,472 ?EEEEEE?TTSTTS???----------------------------------------------S?GGGGSHHHHHHHHHHHHH-HHT?S?------EEEEEETHHHHHHHHHHHH?GG----GEEEEE-EES???????SSS-----------------------------------------------------------------------?HHHHHH-T?G----------------------GGHHHHHTTSTTHHH-----------HHHHHTHHHHHHHHS??TTS?????TTHHHHT--------SSSTTS?SS????TTS?HHH---HHHHHH----HHHHHTTHHHH----------HTTTTHHHHHHHHHTTTT??------??S?EEEEEETT?S---SS?GGGGTT-GGGTSTT-------?--EEEEETT?-?S?H--------HHHSHHHH--HHHHHH 2G4L|A PF00562.23_RNA_pol_Rpb2_6_seed 117 1198 !Q:3,3|6,6|13,13|16,16|18,40|44,46|49,50|53,119|123,127|131,131|135,135|137,139|142,143|146,148|150,150|153,153|156,156|164,169|178,178|189,190|193,193|196,196|203,203|213,213|221,223|227,238|242,243|247,248|250,251|253,254|257,269|277,279|282,285|289,318|320,338|340,340|342,347|352,352|356,357|359,359|361,371|382,386|388,388|390,393|396,397|400,402|404,404|414,415|419,421|463,464|466,595|600,602|609,612|648,652|655,661|663,663|674,676|679,679|683,683|687,689|693,696|701,701|703,703|705,705|708,712|717,717|726,726|728,746|761,761|774,774|779,779|791,810|813,813|815,819|822,823|837,840|843,844|848,938|940,957|961,991|997,1017|1019,1023|1026,1107|1113,1128|1130,1130|1134,1135|1137,1144|1147,1147|1158,1158|1161,1161|1164,1165|1172,1172|1175,1175|1179,1180|1183,1187|1189,1190|1193,1193 Q:0,2|4,5|7,12|14,15|17,17|41,43|47,48|51,52|120,122|128,130|132,134|136,136|140,141|144,145|149,149|151,152|154,155|157,163|170,177|179,188|191,192|194,195|197,202|204,212|214,220|224,226|239,241|244,246|249,249|252,252|255,256|270,276|280,281|286,288|319,319|339,339|341,341|348,351|353,355|358,358|360,360|372,381|387,387|389,389|394,395|398,399|403,403|405,413|416,418|422,462|465,465|596,599|603,608|613,647|653,654|662,662|664,673|677,678|680,682|684,686|690,692|697,700|702,702|704,704|706,707|713,716|718,725|727,727|747,760|762,773|775,778|780,790|811,812|814,814|820,821|824,836|841,842|845,847|939,939|958,960|992,996|1018,1018|1024,1025|1108,1112|1129,1129|1131,1133|1136,1136|1145,1146|1148,1157|1159,1160|1162,1163|1166,1171|1173,1174|1176,1178|1181,1182|1188,1188|1191,1192|1194,1197 SEE?SS?EEEEEE?SS?E-----------------------EEE?-?SS??SS?--------------------------------------------------------------????EEE???-?SEE?TTS-B---EE??EE--?S?TT?EE?TTSEEEE-----?SSEETTEE?SSEEEEEEES??TT-SS?SSEEEE?HHHHHTTTT?EEEEEEE---EEE?----------?EET--TEE-?B??S??SS?-----------?THHHHHB--?SS----SBB-----------------------------?T-------------------T?E------EETT?EEE??B?B--???????--HHHHHHHHHH?????S-B????EE??TT--?E-EEEEEEEEE??TTS???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSSS??G----------------------------------------------------------------------------------------------------------------------------------GGSS???SHHHHS????SSTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS?????SS-?-----S?EEEEEEEEEE???TT?BEE?SSS???EEE????GGGS?B?S-SS?--??SEEE?GGGTTTTT?T-------------------HHHHHHHHHHHHHH-HHHHHHHHHSSS?TTSS?HHHHHHHHHTT--------------------TT?S?????SS??TTHHHHHHHGGGS?-??EE??SSS?---------------------------------------------------??-------------------------------------T------------------THH-------------------------------HHHHT---------------------T-----TT?--------------------------------------------------------------------------------?TTSEE--------------??B?SSS??B?-------SS?EEEEEEEEEE?SS?TT--TSEEEE-SS?EEB--SS-----S??EE?SSSS 1K83|B PF00563.15_EAL_seed 137 364 !Q:7,9|11,12|16,18|20,20|26,29|31,31|34,36|38,38|42,47|50,52|67,67|70,72|76,81|89,93|95,96|104,104|114,114|124,124|126,127|130,131|133,134|139,143|145,145|153,155|162,164|168,174|178,180|192,195|200,209|214,215|220,223|225,225|229,231|234,234|242,243|247,247|249,250|254,254|259,263|266,266|269,269|274,275|280,282|294,301|310,317|319,319|324,327|331,332|342,348|351,353|358,363 Q:0,6|10,10|13,15|19,19|21,25|30,30|32,33|37,37|39,41|48,49|53,66|68,69|73,75|82,88|94,94|97,103|105,113|115,123|125,125|128,129|132,132|135,138|144,144|146,152|156,161|165,167|175,177|181,191|196,199|210,213|216,219|224,224|226,228|232,233|235,241|244,246|248,248|251,253|255,258|264,265|267,268|270,273|276,279|283,293|302,309|318,318|320,323|328,330|333,341|349,350|354,357 HHHHHHH---H--HTT--?E-EEEEE----E-EE---E-TTT??----EE---EEEEEEEEEETTTE-EE--?GGG------THHHHHH-----T--THHHHHH-HHHHHHHHH-HHHHHHHTT?S-?TT??E--EEEE----?G-GGGGGGH---HHHHHH---HHH-------HHH???GGGEEEEEEGG----GGGG?--------?HHHH--HHHH----H-HHH---HT?EEEEEEE--TSS?B-?HHH-HHHS???--EE-EE?HHHH--TTTT---TSHHHHHHHHH--------HHHHHHHT--------T?EEEE????SHH--HHHHHHHTT??-----EE?--STTT---??? 3GFZ|A PF00564.19_PB1_seed 53 112 !Q:0,0|9,9|12,12|21,21|23,23|26,30|44,53|55,55|62,62|66,67|71,72|88,89|91,98|102,102|105,105|111,111 Q:1,8|10,11|13,20|22,22|24,25|31,43|54,54|56,61|63,65|68,70|73,87|90,90|99,101|103,104|106,110 ?EEEEEEEE?SS?EEEEEEEE?S?TT???-?HHHHHHHHHHHHT?---------S?EEEEEE?SSS-?EEE??SHHHHHHHHHHHTTS??B--------TTB?SS?EEEEE? 4IC7|B PF00565.12_SNase_seed 18 139 !Q:8,10|12,13|17,32|35,35|52,52|54,54|60,60|63,64|67,67|71,71|80,88|102,102|105,109|112,113|115,115|133,133|137,138 Q:0,7|11,11|14,16|33,34|36,51|53,53|55,59|61,62|65,66|68,70|72,79|89,101|103,104|110,111|114,114|116,132|134,136 EEEETTEE???S??TTT----------------SS?TTHHHHHHHHHHHHHT?S?EEEEE?SS?-SB?TTS?EEEEEEET---------TEEHHHHHHHTTS?EE??-??TT--S?TTHHHHHHHHHHHHHTT?GGG?? 4K2L|A PF00566.13_RabGAP-TBC_seed 101 374 !Q:7,12|19,50|64,65|68,68|74,74|83,92|96,97|105,105|110,110|123,123|125,127|129,129|131,138|140,142|154,176|180,181|185,204|214,224|228,228|238,242|245,246|253,255|263,263|266,266|269,271|276,276|278,278|281,286|288,288|290,291|295,295|301,304|309,309|312,312|316,316|318,318|324,327|335,338|340,340|342,346|349,349|353,353|358,358|361,361|365,367|370,370 Q:0,6|13,18|51,63|66,67|69,73|75,82|93,95|98,104|106,109|111,122|124,124|128,128|130,130|139,139|143,153|177,179|182,184|205,213|225,227|229,237|243,244|247,252|256,262|264,265|267,268|272,275|277,277|279,280|287,287|289,289|292,294|296,300|305,308|310,311|313,315|317,317|319,323|328,334|339,339|341,341|347,348|350,352|354,357|359,360|362,364|368,369|371,373 GGGHHHH------HHHHTT???----------------------------?HHHHHHHHHHTTS??TT-HHHHH-HHHTTSST----------TST--TTSSTTS-HHHH-HHHHHHHHHHHH?T---T-T?-------S?--TTHHHHHHHHH-----------------------HHS-?HHH--------------------HHHHHHHHH-----------HTS?GGGGTHHHH-----HH--HHHHHH---HHHHHHH-HH?HH---HHHH-H-HH------H-T??GGG-TSHHH----HHHT-TT-TTS?H-HHHHH----HHHHHHH----H?T-----TH-HHH-HHHH-HH-HHT---HH-HHH 3QYE|A PF00567.19_TUDOR_seed 48 150 !Q:0,1|4,4|15,15|24,26|28,29|51,64|67,67|78,79|87,92|96,96|105,105|109,110|114,114|122,125|131,134|136,139|141,142 Q:2,3|5,14|16,23|27,27|30,50|65,66|68,77|80,86|93,95|97,104|106,108|111,113|115,121|126,130|135,135|140,140|143,149 ??TT?EEEEEEEEEE-ETTEEEEE---E??TTHHHHHHHHHHHHHHHTSSS??-----????-??TT?EEEEEETTTT--EEEEEEE------EEE?SSSEEEEE?TTT??EEE-EEGGGEE???-GGGSS----S---?B??EEEEESS 3NTK|A PF00568.18_WH1_seed 8 119 !Q:0,0|3,6|8,8|22,23|32,36|62,62|64,67|72,73|76,78|80,82|90,90|94,95|101,101|103,103 Q:1,2|7,7|9,21|24,31|37,61|63,63|68,71|74,75|79,79|83,89|91,93|96,100|102,102|104,118 ?SS????E-EEEEEEEEEEEEE--ETTTEEEE-----EEEEEEEEEEETTTTEEEEEEEETT-T????EEEE??SS???B???SSEEEEE?SSS--EEEEE?S?HHHHHHHHHHHHHHH 4HAV|B PF00569.12_ZZ_seed 10 46 !Q:0,0|3,3|12,13|27,27|30,30|37,38|40,42|46,46 Q:1,2|4,11|14,26|28,29|31,36|39,39|43,45 ?SS?EEETTTTE--EESSEEEESSSSS?EE?HHHHHH--H???SSE- 2E5R|A PF00570.18_HRDC_seed 147 79 !Q:0,0|16,16|20,21|23,23|25,25|30,31|42,45|54,56|59,60|66,66|72,73 Q:1,15|17,19|22,22|24,24|26,29|32,41|46,53|57,58|61,65|67,71|74,78 ?HHHHHHHHHHHHHHH-HHH--T-S?HHHH??HHHHHHHHHH-???SHHHHHTS---TT??HHHHH-HHHHH--HHHHH 2E1E|A PF00571.23_CBS_seed 850 120 !Q:0,119 Q: ????--???--------------????--????----????-????--???-----???------??-???-?-----??------??-----------????--??-???????????? 2YZQ|A PF00572.13_Ribosomal_L13_seed 115 173 !Q:0,0|3,7|10,10|30,30|32,32|35,36|38,44|47,49|53,53|55,56|58,69|73,75|77,79|81,86|91,94|96,96|103,103|105,107|114,117|120,125|131,131|133,134|147,148|152,153|155,156|160,167|170,172 Q:1,2|8,9|11,29|31,31|33,34|37,37|45,46|50,52|54,54|57,57|70,72|76,76|80,80|87,90|95,95|97,102|104,104|108,113|118,119|126,130|132,132|135,146|149,151|154,154|157,159|168,169 ?EE??--?SS?BTTSSHHHHHHHHTTTTSS?S?SS--S????--?EE???SSS?B??S------------TTT---S???B???--?SBSS????B?HHHHHH-S--?TTHHHH----HH------HHTTS?T--THHHHHHHHHEE??SSS??S-?GGG------??EE??? 2ZJQ|G PF00573.17_Ribosomal_L4_seed 165 432 !Q:2,6|13,21|34,126|130,130|136,145|162,162|164,164|170,183|185,196|198,221|232,248|251,277|281,294|300,325|329,358|369,369|373,373|378,381|384,385|388,399|402,403|413,416|427,427 Q:0,1|7,12|22,33|127,129|131,135|146,161|163,163|165,169|184,184|197,197|222,231|249,250|278,280|295,299|326,328|359,368|370,372|374,377|382,383|386,387|400,401|404,412|417,426|428,431 EE?---?HHHHSS-----??-?HHHHHHHHHHHH??-----------------?????????-???????----????????????????????--------------???????????????-?-?HHH-HHHHH----------HHHHHHHHHHHHHHHT-T?EEEES-----?--?-?--?S------------S??----------------------HHHHHHHHHH-----------------TT?--------------------------TTS-------------?EEEEE?--------?---------------?SHH------------------------------HHHHHHHHTT?TTE-EEEE????SS??SS------??????TT??HHHHHHSSE----EEEEHHHHHH-HHHH 2ZJQ|C PF00574.18_CLP_protease_seed 86 209 !Q:0,9|11,11|16,16|26,26|28,28|30,31|41,41|50,50|54,54|62,63|65,65|80,80|83,83|90,90|105,105|108,110|114,114|116,116|118,118|122,139|163,163|165,168|175,180|186,186|189,189|191,192|201,201|205,208 Q:10,10|12,15|17,25|27,27|29,29|32,40|42,49|51,53|55,61|64,64|66,79|81,82|84,89|91,104|106,107|111,113|115,115|117,117|119,121|140,162|164,164|169,174|181,185|187,188|190,190|193,200|202,204 ????---???T-HHHH-HHHTTEEEE?S?B-?HHHHHHHHH-HHHHHHHH?SSS?EEEEEEE??B?HHHHHHHHHHHHHS-SS?EEEEEE-EEEETHHHHHHTTS?TT?--EEE?T-T?EEE????---??????--???HHHHHHHHHTTHHHHHHHHHHHH-H-???HHHHHH------HHHTT?EE?H--HHHHHHTS?SEE???? 2ZL3|A PF00575.18_S1_seed 51 90 !Q:0,2|17,18|25,25|27,28|31,33|35,36|41,41|44,57|59,59|64,65|68,68|77,78|81,84|89,89 Q:3,16|19,24|26,26|29,30|34,34|37,40|42,43|58,58|60,63|66,67|69,76|79,80|85,88 ???TTSEEEEEEEEEET--TEEEEE?S--SS???B??TTSS?SS------------??S?HHHH??TT?EEEEEEEE??TT??-?EEEE? 2B8K|G PF00576.16_Transthyretin_seed 26 143 !Q:0,1|15,16|18,18|23,32|36,39|51,52|58,59|61,62|64,64|67,69|78,78|88,106|108,108|110,110|122,123|125,125|141,142 Q:2,14|17,17|19,22|33,35|40,50|53,57|60,60|63,63|65,66|70,77|79,87|107,107|109,109|111,121|124,124|126,140 ??EEEEEEETTTTEE??S?EEEE----------EEE?---SSSEEEEEEEE??TTSEE--S??S?SS???SEEEEEEE?HHHHHHHTT?----------------??S?S?EEEEEEESSTT--S?EEEEEEEETTEEEEE?? 3ESN|A PF00577.15_Usher_seed 34 645 !Q:19,20|26,42|68,69|74,76|86,86|91,91|97,100|108,108|127,127|134,139|143,147|154,154|158,158|165,169|172,174|177,177|188,189|191,197|201,203|214,214|229,229|259,259|263,268|282,284|299,299|302,304|313,337|341,341|344,345|356,357|360,363|378,387|389,393|407,407|419,419|423,423|425,430|447,447|450,455|457,457|471,471|475,475|490,491|507,508|520,520|523,523|532,532|535,537|554,554|561,566|574,574|577,579|581,581|588,589|591,591|593,594|603,605|609,609|615,615|620,620|627,627|633,633|635,635|638,638|644,645 Q:0,18|21,25|43,67|70,73|77,85|87,90|92,96|101,107|109,126|128,133|140,142|148,153|155,157|159,164|170,171|175,176|178,187|190,190|198,200|204,213|215,228|230,258|260,262|269,281|285,298|300,301|305,312|338,340|342,343|346,355|358,359|364,377|388,388|394,406|408,418|420,422|424,424|431,446|448,449|456,456|458,470|472,474|476,489|492,506|509,519|521,522|524,531|533,534|538,553|555,560|567,573|575,576|580,580|582,587|590,590|592,592|595,602|606,608|610,614|616,619|621,626|628,632|634,634|636,637|639,643 EEEEEEEEEETTEEEEEEE--EEEEE????------???????EEEEEEEEEEEETTTTEEEEEEEEE??SSSS???EEEEEEEEE?GGGS?GGGSS????EEEEESS-SEEEEEEETTEEEEEEEE?SEEEEE??????TTS---??EEEEEE?SSS?EEEEEE?????TT???TT?EEEEEEEEEE??S------?TTB???EEEEEEEEEE?GGGEEEEEEEEEET-TEEEEEEEEEEEEETTEEEEEEEEEEEEE?TTS?-----EEEEEEEEEEEEE???TTSEEEEEEEEEEE?TT???HHHHHBSS?????????-???????????????TTS?EE--EEEEEEEEEE?-SS----SEEEEEEEEEEEES----------S?????EEEEEEEEEEETT-EEEEEEEEEEE?SSS?S?-----EEEEEEEEEEESGGGS?TT----??S-GGGGEEEEEEEEE?SSS?EEEEEEEEEEESTT??EEEEEEEEEEESTTT??EEEEEEEEEEE?SS?EEEEEEEE?SS--?EEEEEEEEEEEEEETT-EEEEES???---SSEEEEE?TT-??S?BBTTST--T?B??TTSEEEES???TTS?EEEEB?GGGS?TTEEES?SEEEE?B?TT?EEEEE?- 3RFZ|B PF00578.16_AhpC-TSA_seed 124 217 !Q:4,12|18,20|23,23|25,30|32,34|37,37|41,41|45,47|50,51|59,62|64,65|67,68|72,74|84,84|89,89|92,92|95,95|103,105|108,116|125,125|130,142|144,144|147,147|151,154|157,157|165,165|167,167|170,192|195,195|197,197|204,204|207,210 Q:0,3|13,17|21,22|24,24|31,31|35,36|38,40|42,44|48,49|52,58|63,63|66,66|69,71|75,83|85,88|90,91|93,94|96,102|106,107|117,124|126,129|143,143|145,146|148,150|155,156|158,164|166,166|168,169|193,194|196,196|198,203|205,206|211,216 TTSB?-?--?--?EEEEE--?TT-S--?---E---EE-EEG-GGG---TT--SEEEEEE---?S?-S??SSS?-?TTHHHHHTH-HHHH-HT-TE-EEEEEES-??HH---------HHHHHHTS?GGGT----------???S?SS?EEE?---TT?HHHHHTT?B?SS-----------------------SS?B?EEEEEE?TT----SBEEEE 1URM|A PF00579.20_tRNA-synt_1b_seed 40 392 !Q:2,2|5,6|13,13|19,19|23,23|37,41|44,44|51,51|58,74|87,87|91,91|104,107|110,110|112,116|127,129|142,142|150,150|153,158|166,166|168,178|180,181|204,206|211,211|232,234|239,240|245,246|250,252|257,264|266,266|271,272|281,283|285,285|288,288|293,293|305,305|308,309|319,322|324,335|345,347|351,351|353,356|388,391 Q:0,1|3,4|7,12|14,18|20,22|24,36|42,43|45,50|52,57|75,86|88,90|92,103|108,109|111,111|117,126|130,141|143,149|151,152|159,165|167,167|179,179|182,203|207,210|212,231|235,238|241,244|247,249|253,256|265,265|267,270|273,280|284,284|286,287|289,292|294,304|306,307|310,318|323,323|336,344|348,350|352,352|357,387 HH-HS??EEEEEE?TTSSS?BGG-GHHHHHHHHHHHH-----HT?EEEEEE?TTGGGT?????????????????HHHHHHHHHHHH-HHH-HHHHHHHHHHTT????SS?B??---EEETHHHHTT?--BHHHHHHHTTTT?BSHHHHT?HH------HHHHHHS-S-----------S??BHHHHHHHHHHHHHHHHHHHHH???EEEE?GGGHHHHHHHHHHHHHHHHT???HHHH--HHHS??STT???EEEE??----??B?SSSS--BTTEETTE---E?BS?GGGS?HHHHHHHHHHS?HH--HHHHHHHHH????H------------HHHHHHHHH---HTT?T----TTTHHHHHHHHHHHHHHHHHHHHHHHHHHHT???? 3P0I|A PF00580.16_UvrD-helicase_seed 36 700 !Q:0,1|10,14|17,17|23,23|26,27|42,42|45,48|52,59|66,66|80,98|110,110|112,120|154,178|181,181|184,185|198,212|224,224|234,235|238,238|241,242|272,384|387,389|392,393|425,445|463,463|474,488|517,517|557,557|568,601|605,618|620,620|630,630|641,642|654,654|656,656|660,667|669,669|675,675|679,681|686,687 Q:2,9|15,16|18,22|24,25|28,41|43,44|49,51|60,65|67,79|99,109|111,111|121,153|179,180|182,183|186,197|213,223|225,233|236,237|239,240|243,271|385,386|390,391|394,424|446,462|464,473|489,516|518,556|558,567|602,604|619,619|621,629|631,640|643,653|655,655|657,659|668,668|670,674|676,678|682,685|688,699 ??HHHHHHHH?---?SS?EEEEE?TT??HHHHHHHHHHHHHS?SS????GGG--------EEEEES?HHHHHHHHHHHHH-------------------HHHHHHHHSTT?H---------HHHHHHHHTTTSEEEEHHHHHHHHHHHHGGGTT-----------------------??TT?EE??HHHHHHHHHHHH---------------HHHHHHHHHHT?HHHHHHHHH--HS?TT??HHHHHHHHHHHHHHTTSSSHHHHHHTSHH-----------------------------------------------------------------------------------------------------------------HH???TT??TTTSTTHHHHHHHHHHHHHHHHHHHHHHHHH??????---------??????HHHHHHHHHHHHHHTSS?HHHHHHHTTT???????????????HHHHHHHHHHHHHHHHHHHHHHHHHTTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTEE?HHHHHHHHHH----------------------------------HHB?????-----????B?HHHHHHHHH?SEEEESSGGG??HHHHHHHHHHS?S?TTS--------S?EEEEE?GGG???TTTT??HHHHHHHHHHSB 1W36|B PF00581.15_Rhodanese_seed 147 256 !Q:0,0|3,4|11,19|27,27|29,37|41,70|75,86|88,97|99,102|104,104|107,111|113,113|115,116|121,137|139,139|143,143|145,146|154,159|165,168|172,178|180,181|185,200|213,217|223,227|229,236|238,242 Q:1,2|5,10|20,26|28,28|38,40|71,74|87,87|98,98|103,103|105,106|112,112|114,114|117,120|138,138|140,142|144,144|147,153|160,164|169,171|179,179|182,184|201,212|218,222|228,228|237,237|243,255 ?HH--HHHHTT---------TTSEEEE?S--------?HHH------------------------------HHTS????????????S--------??S----B?TT?----E-E??GGGG-----------------B?TTS?B??HHHHHHH------HHHHT?--?TTS------?E--EEE?---------------SSHHHHHHHHHH-----HHTTS---??S-------?E-----EEESSHHHHHTTS 3P3A|A PF00582.21_Usp_seed 231 191 !Q:0,1|8,11|18,18|27,29|34,34|37,37|46,61|73,99|107,109|133,133|142,154|157,158|160,161|164,166|168,168|170,170|179,179|182,184|188,188|190,190 Q:2,7|12,17|19,26|30,33|35,36|38,45|62,72|100,106|110,132|134,141|155,156|159,159|162,163|167,167|169,169|171,178|180,181|185,187|189,189 ??SEEEEE??--SSHHHH-HHHHHHHH---HHHH-HT?EEEEEEEE????????????????HHHHHHHHHHH---------------------------HHHHHHH???GGGEEEEESSHHHHHHHHHHHTT?SEEEEESS?------------TT??S?-SS---S?H-HHHHHHHH?SS--?EEE-E? 3AB8|A PF00583.19_Acetyltransf_1_seed 241 148 !Q:15,15|18,65|67,67|76,82|90,90|106,107|110,118|125,125|129,130|133,135|142,142|146,146 Q:0,14|16,17|66,66|68,75|83,89|91,105|108,109|119,124|126,128|131,132|136,141|143,145|147,147 EEETTEEEEEEEEEE?TT------------------------------------------------S?EEEEEEEE?------GGGTTSS-HHHHHHHHHHHHHHH--TT-------??EEEEEE-ETT-?HH---HHHHHH-HTT?E 2PR8|A PF00584.15_SecE_seed 185 61 !Q:0,0|4,5|15,15|25,25|48,48|56,56 Q:1,3|6,14|16,24|26,47|49,55|57,60 ?TTT-?SSSHHHHHH-HHHTTTTTS?HHHHHHHHTTHHHHHHHHHHHT-HHHHHHH-HHTS 3DIN|D PF00585.13_Thr_dehydrat_C_seed 16 94 !Q:7,8|16,17|22,22|35,36|44,46|48,48|51,51|59,59|78,78|86,86 Q:0,6|9,15|18,21|23,34|37,43|47,47|49,50|52,58|60,77|79,85|87,93 HHHHHHH??EEEEEEE??BSSS?SHHHHHTTSSSE--EEEEEEE???S-SB?EEEEEEE?SSTHHHHHHHHHHHTSSS?EEETTSS?HHHHHTG 1TDJ|A PF00586.19_AIRS_seed 856 206 !Q:0,5|8,34|37,45|55,55|57,58|67,72|76,78|81,83|98,99|103,104|108,108|117,123|126,132|136,175|177,177|190,191|195,198 Q:6,7|35,36|46,54|56,56|59,66|73,75|79,80|84,97|100,102|105,107|109,116|124,125|133,135|176,176|178,189|192,194|199,205 ?-????EE???------------------------TT-?-------SSEEEEEEE-E??THHHHHHH------HTT-??SS---HHHHHHHHHHHHHH--TTT?-EEE-EEEEEEEE-------SS-?----?HHH----------------------------------------H-HHHHHHHHHHHH--HHT?---EEEEEEE 3C9R|A PF00587.20_tRNA-synt_2b_seed 112 392 !Q:14,15|20,20|23,26|37,37|48,50|54,56|58,68|72,73|83,101|103,105|113,113|117,117|134,135|141,169|177,177|179,179|183,184|187,189|194,194|196,196|200,200|206,206|211,211|213,213|232,234|236,236|246,246|248,250|252,258|264,264|277,278|282,284|293,293|299,299|303,307|312,314|329,330|345,345|348,350|353,360|369,370|374,379|389,389 Q:0,13|16,19|21,22|27,36|38,47|51,53|57,57|69,71|74,82|102,102|106,112|114,116|118,133|136,140|170,176|178,178|180,182|185,186|190,193|195,195|197,199|201,205|207,210|212,212|214,231|235,235|237,245|247,247|251,251|259,263|265,276|279,281|285,292|294,298|300,302|308,311|315,328|331,344|346,347|351,352|361,368|371,373|380,388|390,391 HHHHHHHHHHHHTT--TTTT?EE????SEEEHHHHHH-TTHHHHSEEE---EEE---B-----------TTT??EEEHHHHHH-------------------H---HHHHHHT?SSS?HHHHHHHHHHHTTTTT??HHHHH-----------------------------HHHHHTT?B?TTT??BB???EEEE?S?EEE?SSTTS?EEEE?S?SHHHHHHTHHHHHHHTTT?--S?EEEEEEEEE-E???S----???SGGGS?SEEEEEEEEEEE?-STT???TTGGGTTT?EEEEE?HHH-----HHHT???EEEEHHHHHHTTSS??HHHHHHHHHHHHHH-HH---TT??------GGGEEEEE??TTT??????EEEEEEEEE-TT 3RAC|A PF00588.14_SpoU_methylase_seed 139 205 !Q:0,0|8,10|26,27|33,34|40,45|48,51|56,56|61,61|66,67|72,74|76,76|80,80|85,86|91,91|93,94|97,98|102,106|108,110|112,112|115,120|124,134|137,150|165,165|172,172|174,174|176,177|181,184|189,193|201,201 Q:1,7|11,25|28,32|35,39|46,47|52,55|57,60|62,65|68,71|75,75|77,79|81,84|87,90|92,92|95,96|99,101|107,107|111,111|113,114|121,123|135,136|151,164|166,171|173,173|175,175|178,180|185,188|194,200|202,204 ?EEEEEES???HHHHHHHHHHHHHHT?-SEEEE--ESSSS?--???HH----HHHH-HTTH-HHHS?-EEEE---S?HHH-HHHH--HHHT-T-?EE--EEE----?T---T?SE------EGG-----------GS----???-------SSEEEEEEBTTTBS?HHHHHT?S-E--EEE???-SSSS-????HHHHHHH-HHH 1IPA|A PF00589.17_Phage_integrase_seed 35 257 !Q:0,3|13,13|15,15|18,21|32,37|45,47|54,54|59,59|70,85|87,87|91,91|93,95|100,104|122,125|130,155|160,160|162,172|177,178|193,197|200,205|209,210|226,226|228,228|230,230|236,243|246,246 Q:4,12|14,14|16,17|22,31|38,44|48,53|55,58|60,69|86,86|88,90|92,92|96,99|105,121|126,129|156,159|161,161|173,176|179,192|198,199|206,208|211,225|227,227|229,229|231,235|244,245|247,256 ????HHHHHHHHH?S?TT----SHHHHHHHHH------HHHHHHH???HHHHTT?BGGG-EETTTTEEEE----------------E?SSS?E---EEEE??---HHHHHHHHHHHHHTHHH----HHTT????----------------------BSSB?T-----------TSSB??HHHHHHHHHHHHHH-----TT??----GGG??HHHHHHHHHHHHHHH?S-S?GGGSS????????HH-HHHHHHHHHH 1OUQ|A PF00590.15_TP_methylase_seed 171 387 !Q:0,0|10,12|14,14|18,18|27,27|29,29|33,37|39,42|44,44|46,65|67,72|74,74|82,82|86,108|113,154|163,164|172,175|181,181|184,184|189,190|198,198|200,201|206,207|210,214|217,218|221,224|235,236|238,239|246,246|252,259|261,262|265,266|269,272|280,288|290,290|296,303|305,305|308,309|311,317|326,336|340,345|347,348|351,352|360,364|369,369|371,372|374,375|378,378 Q:1,9|13,13|15,17|19,26|28,28|30,32|38,38|43,43|45,45|66,66|73,73|75,81|83,85|109,112|155,162|165,171|176,180|182,183|185,188|191,197|199,199|202,205|208,209|215,216|219,220|225,234|237,237|240,245|247,251|260,260|263,264|267,268|273,279|289,289|291,295|304,304|306,307|310,310|318,325|337,339|346,346|349,350|353,359|365,368|370,370|373,373|376,377|379,386 ?EEEEEEESS?--G-GGS?HHHHHHHT-T?SEE-----E----E?T--------------------T------S?HHHHHHS?TTS-----------------------EEEE??????---------?????----------------------HHHHHHHH--HHHHHTT??--EEEEE-EB?TTSS--SSHHHHH-H--HHHH--TT??---EE--EE????HHHHHHHHTT??S?-BTTTBS?EEEEE-------?S??TT--SS????HHHHTSS---------S?EEEEE--------S?GG--G-------HHHHHHHH-----------HHT------T??TT?-EEEEEES-----TTST-T-?E--EE-EEEGGGHH 2DV7|A PF00591.16_Glycos_transf_3_seed 21 281 !Q:9,11|13,15|17,18|31,31|33,33|39,49|57,57|59,65|82,90|97,101|103,104|113,114|116,116|118,120|126,126|143,143|145,145|157,162|165,166|170,170|178,178|181,183|191,191|197,202|207,207|211,211|220,220|227,228|235,235|256,262 Q:0,8|12,12|16,16|19,30|32,32|34,38|50,56|58,58|66,81|91,96|102,102|105,112|115,115|117,117|121,125|127,142|144,144|146,156|163,164|167,169|171,177|179,180|184,190|192,196|203,206|208,210|212,219|221,226|229,234|236,255|263,280 STTEEEEEE???S???B??HHHHHHHHHHHH-T?EEEEE???????????HHHHHHT-T???-???HHHHHHHHHHHSEEEE?????????HHHHTT?????S??THHHHGGG??T-T???EEEEE?SSHHHHHHHHHHHHHT-T?SEEEEEEETTS-----?SS??SSS?EEEEEEE-TT---EEEEEEE?GGGGT??????TTTB?SSH-HHHHHHHH-HHHSSS??HHHHHH-HHHHHHHHHHHHHHHTSSSS-------HHHHHHHHHHHHHHTHHH 1OTP|A PF00593.19_TonB_dep_Rec_seed 666 635 !Q:7,11|17,30|37,38|46,171|189,196|205,205|217,217|221,222|226,228|261,408|416,416|420,420|423,423|426,426|430,430|442,442|448,448|459,460|473,476|484,484|488,488|494,509|516,518|522,524|527,541|545,547|549,571|574,574|578,625 Q:0,6|12,16|31,36|39,45|172,188|197,204|206,216|218,220|223,225|229,260|409,415|417,419|421,422|424,425|427,429|431,441|443,447|449,458|461,472|477,483|485,487|489,493|510,515|519,521|525,526|542,544|548,548|572,573|575,577|626,634 EEEEEEE-----EEEET--------------TEEEEE--EEEEEEE???????----------------------------------------------------------------?-----------------------------------------------???????EEEEEEEEEEEEEEGGG--------TEEEEEEE-EEEEEEEEEEE?SSS??STT???EEEEEEEEEEEEEEEEEEEEETTEEEEEEEEE----------------------------------------------------------------------------------------------------------------------------------------------------EEEEEEE?TTS?TT?BS?TTS?SEEEEEEEEEE?SHHHH?EEEEEEEEEE??EEEEETTEEEEE--??EEEEEEE-EEE-ESSSS----------------EEEEEE---EES---TT----------?-???EEE???T-----------------------TS?BEE?-------------------------------------------???-EEEEEEEEE 1XKW|A PF00594.15_Gla_seed 29 42 !Q:0,1|4,7|16,18|40,41 Q:2,3|8,15|19,39 ??SS????STTTTSSS???STTHHHHTTSSHHHHHHHHHH?? 1W2K|L PF00595.19_PDZ_seed 58 110 !Q:5,9|12,13|18,20|24,24|26,26|29,40|45,45|48,49|56,59|62,62|68,69|72,76|79,79|83,84|98,102 Q:0,4|10,11|14,17|21,23|25,25|27,28|41,44|46,47|50,55|60,61|63,67|70,71|77,78|80,82|85,97|103,109 EEEEE?---?SS??SEEE???SSS?S?TT-------?????EEEE?TT--SHHHHH????TT?EEEEE--TT-----EE?SSS-?HHHHHHHHHHTTT-----EEEEEEE 1N99|A PF00596.16_Aldolase_II_seed 502 443 !Q:2,2|4,7|16,16|21,24|27,28|36,65|67,81|87,87|89,89|92,93|95,96|100,104|106,106|109,109|113,117|119,121|123,130|133,136|139,159|161,176|179,182|184,196|209,214|216,216|218,219|224,226|234,234|237,253|255,257|259,269|276,276|278,278|280,288|290,290|292,292|294,319|328,339|345,346|355,361|365,387|391,395|403,404|411,416|418,418|431,434 Q:0,1|3,3|8,15|17,20|25,26|29,35|66,66|82,86|88,88|90,91|94,94|97,99|105,105|107,108|110,112|118,118|122,122|131,132|137,138|160,160|177,178|183,183|197,208|215,215|217,217|220,223|227,233|235,236|254,254|258,258|270,275|277,277|279,279|289,289|291,291|293,293|320,327|340,344|347,354|362,364|388,390|396,402|405,410|417,417|419,430|435,442 HH-H----HHHHHHHH-HTTS-??-TT??EEEEEET------------------------------T---------------TTEEE-E?BS--S??TTT??---G-GG?EEE-----E---T--------TT?--?EE---------------------E?---------------SS---?B?------------TTHHHHHHHHHH-----?T-T??EEEE???HHHHHHH-HH-----------------T??-B-?--?-----?SHHHHT-T?S---------S?B?B-------------?--??------??HHHHHSSH------------HHHHH--HHHHHHHH-------HTT?---------------------?TTT??---EEEETTT--EEEEEE------S-SHHHHHHHHHHH----HHHHHHHH 1DZZ|P PF00598.14_Flu_M1_seed 2 157 !Q:0,0|14,14|33,36|47,47|51,51|68,69|72,75|87,87|91,91|105,106|119,119|136,138 Q:1,13|15,32|37,46|48,50|52,67|70,71|76,86|88,90|92,104|107,118|120,135|139,156 ?HHHHHHHHHHTTS?SSHHHHHHHHHHHHHHTT????HHHHHHHHHT?SSS?HHHHHHHHHHHHHHSS??TT????HHHHHHTSGGG?HHH-HHHHHHHHHHHTT??SHHHHHHHHTTS?HHHHHHHHHHHHTTSS???HHHHHHHHHHHHHHHHHH 1AA7|A PF00599.12_Flu_M2_seed 2 97 !Q:0,22|61,97 Q:23,60 ------------------?????HHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHT?------------------------------------ 2KWX|A PF00600.14_Flu_NS1_seed 3 217 !Q:0,4|26,28|51,52|69,69|71,88|93,93|99,103|122,123|125,125|153,154|162,164|167,169|189,189|194,194|201,216 Q:5,25|29,50|53,68|70,70|89,92|94,98|104,121|124,124|126,152|155,161|165,166|170,188|190,193|195,200 ?????HHHHHHHHHHHHHHHHHHHHS???HHHHHHHHHHHHHHHHHHHHHT??HHHHHHHHHHHHHTTS?S????????-----?????EESS?HHHHH?????SSEEEEEETTEEEEEETT??S?EEEEEEEEEEETTEEEEEEEEEEEETT??EEEEEEE???SS???HHHHHHHHHHHHHHHHHTT?EEEE?HHHHHH???????????????? 2RHK|A PF00601.14_Flu_NS2_seed 4 94 !Q:0,35|59,62|88,93 Q:36,58|63,87 -------------------------------?????HHHHHHHHHHHHHHHHHHHHHHT????TTSHHHHHHHHHHHHHHHHHHHHHH?----- 1PD3|A PF00603.12_Flu_PA_seed 4 742 !Q:0,250|255,268|272,276|279,279|284,285|288,288|292,293|299,299|311,313|322,323|327,327|334,337|347,356|359,359|361,364|372,406|408,409|423,423|425,425|428,428|430,431|433,438|440,442|482,482|486,486|497,497|501,509|521,526|530,530|541,543|554,554|563,576|624,625|631,634|637,640|654,654|673,674|697,697|700,709|719,719|722,722|740,741 Q:251,254|269,271|277,278|280,283|286,287|289,291|294,298|300,310|314,321|324,326|328,333|338,346|357,358|360,360|365,371|407,407|410,422|424,424|426,427|429,429|432,432|439,439|443,481|483,485|487,496|498,500|510,520|527,529|531,540|544,553|555,562|577,623|626,630|635,636|641,653|655,672|675,696|698,699|710,718|720,721|723,739 -----------------------------------?----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------???????????????????TTSS????????----??SSB?????SS?STTB??EE-EES??STTTT?HHHHHHHHHTT???EEEEEEEE??SSS?HHHHHH----HHHHHHHHH??????????SS?B????HHHHHHT?????????----??????????????????????B??THHHHHHHHHTSB?S-SB?S??S??????S???HHHHHHHHHHHHHHSSBHHHHHHHHHHHHHHHHHHHHHS?SSS?BEEEEEEEEE?TTS--------?EEEEEEEEEEE??????STT?EEEEEEEEEE???GGGSTTTTTT?EEEEEEEE???----???????EEEEEEEEEEEEEHHHHHHHHTTTHHHHHHHHHHHHHHHHHHHHTTS??HHHHH----HS????EEEEEETTEEEEE?HHHHHHHHHHHHHHHHHT??HHHHHHHHHHHHHHHHHHHHHH?SS---???????SHHHHHHTT?SS?HHHHHHHHHHHHHHHHH?? 3HW6|A PF00604.12_Flu_PB2_seed 6 782 !Q:0,548|573,577|585,585|592,592|603,603|627,629|643,653|659,660|664,664|669,669|673,673|680,680|684,684|696,699|702,704|706,706|708,708|722,723|727,727|729,729|731,731|738,739|742,742|759,759|762,781 Q:549,572|578,584|586,591|593,602|604,626|630,642|654,658|661,663|665,668|670,672|674,679|681,683|685,695|700,701|705,705|707,707|709,721|724,726|728,728|730,730|732,737|740,741|743,758|760,761 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?GGGGGHHHHHHHHHHHHHHHSHHH-----HHHHHHH?HHHHHT?GGGHHHHHTS?TTTHHHHHHHHHHHHHHHHHSTT???HHHHHHHGGGGSS???????--??SEEEE??SSS?EEEE-SSS?BTTBEE?SSS?EEESSSSEEEE????TT???S-S?BSSSSTTEEEEEE??GGG?S?B?GGGGGT??TT?EEEEEEETTEEEEEEE?SS???????????????????? 2VY6|A PF00605.12_IRF_seed 26 131 !Q:1,2|16,16|32,34|42,45|62,63|68,83|101,107|111,111|114,117|122,130 Q:0,0|3,15|17,31|35,41|46,61|64,67|84,100|108,110|112,113|118,121 S??HHHHHHHHHHHTS?TTSEEEEGGGTEEEE???SSSSSSS??--TTTHHHHHHTTTTTTS??BTTB??-------------?HHHHHHHHHHHHHSSTT???????SSS?SS??-?EEEE??---?--- 1IRG|A PF00606.13_Glycoprotein_B_seed 40 856 !Q:2,2|6,11|17,34|36,36|45,46|48,48|53,53|68,68|70,70|72,72|74,75|86,88|103,103|111,111|123,123|125,128|131,131|134,137|140,142|147,148|150,154|156,162|173,174|179,179|182,182|187,187|191,191|194,194|196,196|199,199|203,204|208,208|212,212|216,216|227,228|230,230|234,238|240,240|243,243|254,254|261,263|268,269|277,277|288,288|305,305|307,307|309,311|316,318|321,321|347,347|350,351|353,355|390,429|431,474|476,477|522,522|534,534|549,549|553,553|557,557|561,561|564,564|566,574|580,583|589,589|594,594|599,633|648,650|654,655|658,659|680,681|686,709|712,712|720,720|723,724|741,741|744,855 Q:0,1|3,5|12,16|35,35|37,44|47,47|49,52|54,67|69,69|71,71|73,73|76,85|89,102|104,110|112,122|124,124|129,130|132,133|138,139|143,146|149,149|155,155|163,172|175,178|180,181|183,186|188,190|192,193|195,195|197,198|200,202|205,207|209,211|213,215|217,226|229,229|231,233|239,239|241,242|244,253|255,260|264,267|270,276|278,287|289,304|306,306|308,308|312,315|319,320|322,346|348,349|352,352|356,389|430,430|475,475|478,521|523,533|535,548|550,552|554,556|558,560|562,563|565,565|575,579|584,588|590,593|595,598|634,647|651,653|656,657|660,679|682,685|710,711|713,719|721,722|725,740|742,743 SS?EEE???-??TTEEE??????????-???????B?EEEEEEEE??S?EEEE?EEEEEEEEEEEEEE?S-S?E--EEEEEEEEEE???HHHHHHTHHHHSEE?SEEEEES-SSSEEEEEGGG?S-???EE?EE????SS???EEES??S?????S??-????EEEEEEEEEE??EEEE?TT?SSEE?SSS?EE?B?TT?SSS--GGG-GGS?BSS?TTTEEEEEEE??B?TTT?---?B?SS?EEEEEEEETT-EEEEEE???HHHH??SEEEEEE-ETTEEEEEET-TEEEEEETTTTEEEEE?S-S???GGGB---SS?HHHHHHHHHHHHHHHTTSSTTTEEE?SS?-E---EEEETTTEEEEEEEEEEGGGGGGHHHHHHHHHTT????????????----------------------??????B?---------------------------------------????S??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?HHHHHHTTSSS?EEEEEETTEEEEEE?EEE?SSS-EEE?SB?B--------?SSSTT----EEESS?EEEE?SSSS??--------------------------------?EEEEEETTTEEESS???EEE??SS??EEEEETTEEEEEETTEEEEE??GGGS???-????????????????????SS?HHHHHHT-SS??HHHHHHHHHHHHHHHS?SS?????-------------------------------------------------------------------------------------------???---?--------? 2GUM|A PF00607.15_Gag_p24_seed 16 239 !Q:13,13|17,17|31,34|45,51|53,53|57,57|65,67|80,87|90,97|101,101|108,110|121,121|124,126|147,151|156,158|161,162|177,180|197,197|208,212|216,216|218,218|224,226|228,228|233,233|235,238 Q:0,12|14,16|18,30|35,44|52,52|54,56|58,64|68,79|88,89|98,100|102,107|111,120|122,123|127,146|152,155|159,160|163,176|181,196|198,207|213,215|217,217|219,223|227,227|229,232|234,234 HHHHHHHHHHHHH-HTT?TTHHHHHHHHTTT?--?HHHHHHHHHH--??---S?HHH-HHHHHHH---HHHHHHHHHHHS????-???TT?-??????HHH-HTTSSS--?HHHHHHHHTS-SS???HHHHHHHHHHHHHHHHHHHH???-?SGGG???TT??SSHHHHHHHHHTSS????HHHHHHHHHTTTTTTS?HHHHHHHHHH?----TTS?H-HHHHH???S?SSTT?S???? 2X8Q|A PF00608.12_Adeno_shaft_seed 63 31 !Q:1,2|6,6|8,8|14,14|18,18|22,22|24,24|27,27|30,30 Q:0,0|3,5|7,7|9,13|15,17|19,21|23,23|25,26|28,29 S??EEE?B?TTEEE?TTS?EEE?B?TT?EE? 1V1H|A PF00610.16_DEP_seed 133 114 !Q:8,10|13,13|15,16|32,35|38,42|45,46|48,48|61,74|84,85|88,104|107,107|109,109 Q:0,7|11,12|14,14|17,31|36,37|43,44|47,47|49,60|75,83|86,87|105,106|108,108|110,113 GGGSEEEE?--SS?E--EEEEEEHHHHHHHHH----HS-----SS??S?HHHHHHHHHHHH--------------HTTSEEESS??SS---------------??SS-S?EEEE 1O7F|A PF00611.18_FCH_seed 157 133 !Q:0,1|7,16|33,33|41,41|57,57|69,77|81,87|91,107 Q:2,6|17,32|34,40|42,56|58,68|78,80|88,90|108,132 ??TTSTT----------TTHHHHHHHHHHHHHH-HHHHHHH-HHHHHHHHHHHHHHH-HHHHHHHHHHH---------HSS??-----HHH-----------------HHHHHHHHHHHHHHHHHHHHHHHHH 2EFK|A PF00612.22_IQ_seed 345 21 !Q: Q:0,20 HHHHHHHHHHHHHHHHHHHHH 1BR1|A PF00613.15_PI3Ka_seed 16 270 !Q:0,9|20,20|24,26|40,40|43,43|51,57|62,62|65,65|68,68|82,91|103,108|123,124|142,198|203,203|216,216|218,218|233,238|240,240|244,244|260,260 Q:10,19|21,23|27,39|41,42|44,50|58,61|63,64|66,67|69,81|92,102|109,122|125,141|199,202|204,215|217,217|219,232|239,239|241,243|245,259|261,269 ?????-????STTTTTTTSS?TTS???HHHHHHHHHTHHH-HT-TSGGGHH-------HHHT-TS?SS?SHHHHHHHHHHHT---???--??HHHHTTTTSTT???---HHHHHHHHHHHHHS??HHHHHHTHHHHHTTGGG?--------------------------------------------------------SSSS?HHHHHHHHHHHH?H-HHHHHHHHHHHHTS------S?HHH-HHHHHHHHHHHHHHT-TTHHHHHHH 4FLH|A PF00614.17_PLDc_seed 48 40 !Q:5,7|15,26|32,35 Q:0,4|8,14|27,31|36,39 TTBEE???EEEETTT------------EEEEE????SHHH 3HSI|A PF00615.14_RGS_seed 74 180 !Q:0,0|7,7|10,10|24,24|26,27|42,69|77,78|91,91|93,93|95,100|114,143|149,149|158,158|172,173 Q:1,6|8,9|11,23|25,25|28,41|70,76|79,90|92,92|94,94|101,113|144,148|150,157|159,171|174,179 ?HHHHHT?HH-HHHHHHHHHHHTT?H--HHHHHHHHHHHHTT?-------------------------??HHHHHHH--HHHHHHHHTSTT?T-T??-???HHHHHHHHHTTSS----------------------------??TTTTH-HHHHHHHH-HHHHTHHHHHHHS--HHHHTT 3UZT|A PF00616.14_RasGAP_seed 115 439 !Q:7,9|13,36|40,40|43,44|50,50|52,53|55,56|61,61|70,73|88,91|96,97|100,100|103,110|129,226|229,230|232,246|248,249|259,259|266,273|280,282|296,296|299,299|302,305|307,308|326,326|330,362|367,368|380,381|386,387|390,395|398,398|406,412|415,418|433,433 Q:0,6|10,12|37,39|41,42|45,49|51,51|54,54|57,60|62,69|74,87|92,95|98,99|101,102|111,128|227,228|231,231|247,247|250,258|260,265|274,279|283,295|297,298|300,301|306,306|309,325|327,329|363,366|369,379|382,385|388,389|396,397|399,405|413,414|419,432|434,438 HHHHHHH---HHH------------------------HHH?SS--SSHHH-H--S??HHHH-HHHHHTTS----HHHHHHHHHHHHHH----HHHH--HH?TT???--???HHHHHHHHHHHHHHHHSS------------------------------------------------------------------------------------------------??SS?-S---------------S??HHHHTTSHH-HHHHHH--------HHHHHH---HHHHHHHHHHHHT-TG-GG----S-?HHHHHHHHHHHHHHHHH?TTS?--------------------------------HHHH--HHHHHHHHIII--IIHH--HH------HS-TTTTTSS----???TT????HHHHHHHHHHHHHH-HHHHT 3FAY|A PF00617.14_RasGEF_seed 148 571 !Q:3,3|17,19|22,25|29,34|36,55|58,87|90,91|96,103|105,107|112,139|141,141|143,148|170,185|202,212|214,233|235,235|249,249|261,261|269,269|274,276|278,289|291,291|299,310|312,341|343,360|367,368|370,374|379,411|414,414|416,420|422,443|445,446|453,478|487,489|491,510|516,559|567,568 Q:0,2|4,16|20,21|26,28|35,35|56,57|88,89|92,95|104,104|108,111|140,140|142,142|149,169|186,201|213,213|234,234|236,248|250,260|262,268|270,273|277,277|290,290|292,298|311,311|342,342|361,366|369,369|375,378|412,413|415,415|421,421|444,444|447,452|479,486|490,490|511,515|560,566|569,570 GGS?HHHHHHHHHHHHH---HH----HTT----??H--------------------HH------------------------------HH--HHHH-------?G---GGTT??-------------------------?H-H------HHHHHHHHHHHHHHHHHHHHH?-?-------------SHHHHHHHHHHHHHHH-----------H--------------------H-HHHTTBHHHHHHH-HHHHHSHHHHT?HHHHHHS?HHHH---H------------H-HHHHHHH------------T----------------------------??H------------------HHHHHH--H-----HHHH---------------------------------TS?S-----S?---------------------B??HHHHHH--------------------------HHHHHHHS---S?-------------------SBSSS--------------------------------------------SEEHHHH--HH 1NVU|S PF00618.15_RasGEF_N_seed 88 223 !Q:0,0|5,5|8,9|17,17|19,19|21,30|32,32|47,48|61,97|101,127|135,149|166,167|169,171|183,183|186,188|190,195|199,199|202,214 Q:1,4|6,7|10,16|18,18|20,20|31,31|33,46|49,60|98,100|128,134|150,165|168,168|172,182|184,185|189,189|196,198|200,201|215,222 ?EEEE?HH--HHHHHHT?S-S??-------?H-HHHHHHHHHGGGTS-?HHHHHHHHHHHH?---------------------------?-??????-HHH---------------------------HHHHHTT???----------??HHHHHHHHHTHHHHHH--H---HHHHHHHHHHH?TH---H------HHH?HH-------------HHHHHHHH 1NVU|S PF00619.16_CARD_seed 60 102 !Q:0,1|14,15|22,24|34,34|36,36|46,49|52,54|59,59|63,64|69,69|74,74|88,89|91,91|99,101 Q:2,13|16,21|25,33|35,35|37,45|50,51|55,58|60,62|65,68|70,73|75,87|90,90|92,98 ??HHHHTHHHHHTT??HHHHHH---HHHHHHHHT?S?HHHHHHHHT--??SS---HHHH-HHH--HHHH-HHHT?HHHHHHHHHHHHH--H?TTGGGGG??? 3KAT|A PF00620.22_RhoGAP_seed 87 234 !Q:0,0|13,13|15,17|19,19|27,29|47,70|75,77|92,92|95,95|98,98|107,107|109,110|114,129|134,154|164,165|168,168|188,189|194,205|207,209|222,226|228,230 Q:1,12|14,14|18,18|20,26|30,46|71,74|78,91|93,94|96,97|99,106|108,108|111,113|130,133|155,163|166,167|169,187|190,193|206,206|210,221|227,227|231,233 ?HHHHHHHHHHHH-H?--S?STTTTTS???HHHHHHHHHHHHHHGGG???---------------------STTT???HHHHHHHHHHHHHH?SS?SS?TTTHHHHH-H--HHH?-------------??HHHH---------------------HHHHHHHHH--HS?HHHHHHHHHHHHHHHHHHH--THHH------------H???HHHHHHHHHHHH?????S--?TTG 3MSX|B PF00621.15_RhoGEF_seed 192 466 !Q:19,20|31,64|68,69|73,81|84,87|89,90|93,93|95,95|105,105|108,112|114,114|121,166|168,169|172,178|182,215|220,222|225,225|229,242|247,247|255,257|266,269|272,273|276,320|325,333|337,343|351,358|362,364|366,375|394,405|410,410|415,417|419,420|423,427|429,430|433,433|435,438|443,450|456,456 Q:0,18|21,30|65,67|70,72|82,83|88,88|91,92|94,94|96,104|106,107|113,113|115,120|167,167|170,171|179,181|216,219|223,224|226,228|243,246|248,254|258,265|270,271|274,275|321,324|334,336|344,350|359,361|365,365|376,393|406,409|411,414|418,418|421,422|428,428|431,432|434,434|439,442|451,455|457,465 HHHHHHHHHHHHHHHHHHH--HHHTHHHHHH?---------------------------------TTT??HHH---------HH----H--HH-T-THHHHHHHH-HH-----H-HHHHHH----------------------------------------------H??SS?------GGG??------------------?-------------HHHH---HH-TTT--------------GGGH-HHHHHHH---HHHHHHHH----HH--HT---------------------------------------------TSHH---------HHH-------HHHHHHH--------HTT?-?S??--------HHHHHTHHHHHHHHHHHH------------HHHH-HHTS-?-T--TS-----T--TH-H----HHHH--------HHHHH-HHHHHHHHH 3P6A|A PF00622.23_SPRY_seed 68 232 !Q:9,9|12,12|14,22|32,97|100,106|111,111|121,121|127,128|130,137|139,139|142,144|147,156|169,172|178,178|184,184|187,189|195,196|198,204|206,206|213,216|222,224|228,231 Q:0,8|10,11|13,13|23,31|98,99|107,110|112,120|122,126|129,129|138,138|140,141|145,146|157,168|173,177|179,183|185,186|190,194|197,197|205,205|207,212|217,221|225,227 SSEEEEEEE?TT?S?--------EEEEEEETT?---------------------------------------------------------------??SS???---?SGGG-TEEEEEEET-TEEEE??S--------S?EE???SS--------??SEEEEEEETTTT----EEEEE-ETTTT-TE---EEEEE?-S????---S?EEEEEE????SSSTT???EEE???? 3UV9|A PF00623.15_RNA_pol_Rpb1_2_seed 33 189 !Q:0,4|14,14|18,18|32,32|38,39|59,59|64,64|66,66|69,70|77,77|80,80|82,85|88,91|94,108|114,115|118,118|124,124|127,128|144,146|152,152|161,162|166,166|172,174 Q:5,13|15,17|19,31|33,37|40,58|60,63|65,65|67,68|71,76|78,79|81,81|86,87|92,93|109,113|116,117|119,123|125,126|129,143|147,151|153,160|163,165|167,171|175,188 ?????SEEEEEEEE?TTS?TTEEEEEHHHHTT?EEEEE??TTTHHHHHHHHHHTTTSSS?EEEE-E?TT??EEETTS?TT-T----TS????TT?--------------EEEEE??TT?EEEEE?SS??SSTTEEEEEEEEESS---SSEEE?GGGSGGGT??TTT?EEEEE???SHHHHHHHHHHTBG 1K83|A PF00625.16_Guanylate_kin_seed 12 198 !Q:0,0|2,3|8,9|14,16|28,28|33,33|35,39|42,42|44,46|49,50|58,60|72,72|79,79|102,104|109,111|121,121|125,126|133,133|135,135|149,150|169,169|173,173|180,180|196,197 Q:1,1|4,7|10,13|17,27|29,32|34,34|40,41|43,43|47,48|51,57|61,71|73,78|80,101|105,108|112,120|122,124|127,132|134,134|136,148|151,168|170,172|174,179|181,195 ?S??EEEE??TTSS---HHHHHHHHHHH?TTTE-E-????EE?S???SS??BTTTBEE?-?HHHHHHHHHTT?EEEEEE-ETTEEEEEEHHHHHHHHHTTSE---EEEE??-HHHHHHHHT?GGG??EEEEEE?S?HHHHHHHHHHSSS??HHHHHHHHHHHHHHHHHH-HTT?SSEEEE?SSHHHHHHHHHHHHH?? 4DEX|A PF00626.17_Gelsolin_seed 54 103 !Q:6,7|18,18|28,28|31,34|44,44|47,48|50,50|66,77|83,83|93,98 Q:0,5|8,17|19,27|29,30|35,43|45,46|49,49|51,65|78,82|84,92|99,102 TTEEEE??GGGTTEEETT?EEEEEEEEE?SS---?EEEEEEEEE?TT--S?HHHHHHHHHHHHHHH------------HHTTS?SEEEEEETT---???HHHH 3CI5|G PF00627.26_UBA_seed 141 46 !Q:0,1|12,13|15,19|22,22|29,29|35,37|46,46 Q:2,11|14,14|20,21|23,28|30,34|38,45 ??HHHHHHHHTT--T---??HH-HHHHHH-HHTTT--?HHHHHHHH- 2JNH|A PF00628.24_PHD_seed 92 76 !Q:1,1|5,20|26,28|30,31|33,33|36,37|40,40|47,48|50,51|53,54|57,69|73,75 Q:0,0|2,4|21,25|29,29|32,32|34,35|38,39|41,46|49,49|52,52|55,56|70,72 S?TTT??-------------?SEEEE?--S--S-SS-?EE?TTSSSS??S--S??SS---------????TTT??? 3C6W|A PF00629.18_MAM_seed 92 264 !Q:1,6|9,12|16,16|18,18|22,22|24,26|29,32|36,36|39,40|43,50|52,52|55,55|57,71|77,77|81,85|88,98|101,101|105,107|109,117|121,131|134,134|137,137|143,144|146,146|149,153|155,155|166,171|181,185|190,190|193,194|196,201|204,204|212,218|220,220|228,228|230,231|233,234|236,237|250,253|256,262 Q:0,0|7,8|13,15|17,17|19,21|23,23|27,28|33,35|37,38|41,42|51,51|53,54|56,56|72,76|78,80|86,87|99,100|102,104|108,108|118,120|132,133|135,136|138,142|145,145|147,148|154,154|156,165|172,180|186,189|191,192|195,195|202,203|205,211|219,219|221,227|229,229|232,232|235,235|238,249|254,255|263,263 E??---?ST----TGG-G?EEE?S---SS?--?EEE-ES??TT--------S?SS?S??????---?????-EEEEE?SSS----?TT?----------EE-EEE???B-------??SSS----------?EE-EE-EEEEE-?S?TT----?E-EEEEEEEEET------TEEEEEEEE-----EEEE-ES??B------SS?EEEEEEE??----?S?EEEEEEE-E??S--S??SSEEEEEEEEEE----SS----???S 2C9A|A PF00630.14_Filamin_seed 132 362 !Q:0,2|6,7|10,13|18,24|26,27|31,35|39,39|41,41|43,44|50,50|52,56|59,60|62,64|66,66|68,73|75,78|82,104|107,108|110,271|274,278|280,282|286,286|288,308|311,312|316,316|320,320|322,322|326,327|330,330|338,341|344,352|354,354|357,358 Q:3,5|8,9|14,17|25,25|28,30|36,38|40,40|42,42|45,49|51,51|57,58|61,61|65,65|67,67|74,74|79,81|105,106|109,109|272,273|279,279|283,285|287,287|309,310|313,315|317,319|321,321|323,325|328,329|331,337|342,343|353,353|355,356|359,361 ???GGG-?EE----ESHH-------H--HEE-----ETT-S?E--EEEEE?T-----TT-?S---S?E------E----EEE----------------------?SS--S----------------------------------------------------------------------------------------------------------------------------------------------------------------??EE-----E---EEE?S---------------------SS--EEE-EEE-E?SSS--SE-EEEEEEE----SS-------?-B?TT?-SEE 2EED|A PF00631.17_G-gamma_seed 50 94 !Q:0,2|21,27|31,32|48,48|52,93 Q:3,20|28,30|33,47|49,51 ???THHHHHHHHHHHHHHHSS--???-?HHH--HHHHHHHHHHHHGGG?TTT???------?-?????????--------------???-???? 1OMW|G PF00632.20_HECT_seed 133 1101 !Q:3,7|13,15|18,23|25,26|30,69|71,108|114,120|124,133|140,166|173,192|194,196|210,216|218,226|228,229|231,231|237,280|284,304|306,316|322,322|324,344|346,346|353,353|359,360|363,364|367,403|405,407|409,409|413,413|415,415|421,433|437,663|666,679|683,684|686,686|689,690|692,694|697,697|699,700|702,703|714,717|721,721|734,741|748,749|753,760|766,766|769,769|779,797|807,808|811,811|814,820|824,845|853,853|856,885|889,889|891,891|907,909|911,912|914,914|917,917|919,919|921,921|923,925|929,930|933,937|941,941|943,1037|1040,1041|1043,1048|1055,1055|1061,1073|1075,1075|1090,1100 Q:0,2|8,12|16,17|24,24|27,29|70,70|109,113|121,123|134,139|167,172|193,193|197,209|217,217|227,227|230,230|232,236|281,283|305,305|317,321|323,323|345,345|347,352|354,358|361,362|365,366|404,404|408,408|410,412|414,414|416,420|434,436|664,665|680,682|685,685|687,688|691,691|695,696|698,698|701,701|704,713|718,720|722,733|742,747|750,752|761,765|767,768|770,778|798,806|809,810|812,813|821,823|846,852|854,855|886,888|890,890|892,906|910,910|913,913|915,916|918,918|920,920|922,922|926,928|931,932|938,940|942,942|1038,1039|1042,1042|1049,1054|1056,1060|1074,1074|1076,1089 HHH-----HHHHT-?-GG------G--SSE----------------------------------------E--------------------------------------ESSTT??----?EEE?---------TTHHHH?--------------------------TTHHHH--------------------H---HHHHHHHHHHHHT-------T?-?-----?S??B?HHHHH--------------------------------------------HHT---------------------T??------??-HHHHH-T---------------------T?HHHHHH-HHHHH--HS??GG-------------------------------------G---T?BSE-E-EEEET-------------TEE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EE--------------EES--S-TT--G---GG?B??T--TTHHHHHHHH----HHH-HHTGGGHHHHHH--------HHHHHT--TTS-?------HHHHT-TS?HHHHHHHHH?-----??-?-------??HHHHHHTEE--EE-TT??-----SSS----------------------HHHHHHH-HH------------------------------HHH-S?HHHHHHHHHHHHSSS???T--T?GG-G?B?S---SSB??EE-----EEE?S?----------------------------------------------------------------------------------------------TT--S----??EEEGGG-TEEEE??----------?S?HHHHHHHHHHHHHT?-?--?-???? 3H1D|A PF00633.18_HHH_seed 104 30 !Q:5,6|8,8|18,19 Q:0,4|7,7|9,17|20,29 HSTTS??S?HHHHTTSTT??HHHHHHHHHH 1X2I|A PF00634.13_BRCA2_seed 25 35 !Q:0,2|7,7|13,13|15,18|30,34 Q:3,6|8,12|14,14|19,29 ???GGGS?EETTS?B????HHHHHHTTTTT????? 1N0W|B PF00635.21_Motile_Sperm_seed 63 129 !Q:6,6|9,9|15,15|17,21|24,25|31,32|36,37|41,42|51,51|60,60|65,65|68,68|75,76|79,84|88,99|108,109|112,112|114,114|116,119|126,127 Q:0,5|7,8|10,14|16,16|22,23|26,30|33,35|38,40|43,50|52,59|61,64|66,67|69,74|77,78|85,87|100,107|110,111|113,113|115,115|120,125|128,128 SSEEES-SS?EEEES?T-----TS?-EEEEE--EEE??SSS-?EEEEEEES?TTTEEESS?EEEE?TT?EEEEEE--EE??????TTS?-?-------??EEEEEEEE??SS?S?H----HHHHHH??T 2YS4|A PF00636.21_Ribonuclease_3_seed 239 356 !Q:21,27|29,31|35,46|53,60|62,64|70,73|80,81|86,97|99,128|131,137|139,141|144,147|149,149|151,182|191,299|302,316|318,336|355,355 Q:0,20|28,28|32,34|47,52|61,61|65,69|74,79|82,85|98,98|129,130|138,138|142,143|148,148|150,150|183,190|300,301|317,317|337,354 HHHHHHHHHHHHHHHHHHHHH-------H?--TTS-?----------HHHHHH--------H---HHHHT----SHHHHH--HHHH------------H------------------------------TT-------H---HH----H?B------------------------------??HHHHHTTG-------------------------------------------------------------------------------------------------------------GG--------------?H-------------------HHHHHHHHHHHHHHHHHH? 2GSL|A PF00637.15_Clathrin_seed 150 186 !Q:4,6|9,10|21,23|26,26|37,47|49,52|67,72|74,75|84,85|87,94|96,96|105,106|109,109|111,111|126,127|129,129|137,141|146,147|153,154|160,166|181,181 Q:0,3|7,8|11,20|24,25|27,36|48,48|53,66|73,73|76,83|86,86|95,95|97,104|107,108|110,110|112,125|128,128|130,136|142,145|148,152|155,159|167,180|182,185 HHHH?--TT??STTTHHHHHT---TT?GGGGTGGGTS??--------?S--??HHHHHHHHHHHHHT------T??HHHHHTTS--S???-----S?TTHHHHHH--HT?S-SHHHHHHHHHHHHT--T?HHHHHSS---?-SSTT??TTGGG--TTTTT???----TTHHHHHHHHHHHH?STHH 1XI4|A PF00638.13_Ran_BP1_seed 8 127 !Q:0,3|26,27|47,47|56,56|60,61|68,69|72,75|81,81|90,90|93,93|98,98 Q:4,25|28,46|48,55|57,59|62,67|70,71|76,80|82,89|91,92|94,97|99,126 ????TTTTEEEEEEEEEEEEEEETTT--TEEEEEEEEEEEEEEETTT-TEEEEEEE?TTT??EEEEEE??TT???-EESTT?SSEEEEEE-EE?TTSS?EEEEEEEEESSHHHHHHHHHHHHHHHHH 4HAV|B PF00639.16_Rotamase_seed 87 146 !Q:0,1|4,4|6,6|14,14|16,18|20,22|24,26|31,34|49,57|66,67|71,73|77,77|82,83|85,88|92,98|101,101|104,104|112,114|116,116|119,122|124,124|126,130|133,134|140,142|144,146 Q:2,3|5,5|7,13|15,15|19,19|23,23|27,30|35,48|58,65|68,70|74,76|78,81|84,84|89,91|99,100|102,103|105,111|115,115|117,118|123,123|125,125|131,132|135,139|143,143 ??EE?S?TTSSSSS?S???S???S???HHHH----HHHHHHHHHHHHSS?-----???HHHHHHSS-?HHH---HHT?SEEE--E---?SSS-------SS?TH-HHHHHHH??-S-SS-??-S?E-----EE--TTEEE???S??- 1ZK6|A PF00640.18_PID_seed 25 188 !Q:12,14|17,18|39,50|59,68|70,70|78,78|90,100|115,115|126,150|159,159|162,165 Q:0,11|15,16|19,38|51,58|69,69|71,77|79,89|101,114|116,125|151,158|160,161|166,187 EEEEEEEEEEEE??-SS??TTHHHHHHHHHHHHHHHHHH------------HHHHHHHT??--??????S-EEEEEEE?SSEEEEEETTT---------??EEEEEEGGGEEEEE?SSSEEEEEEE?????????????????????????EEEEEEEE?TT----HHHHHHHHHHHHHHHHHHHHHT 2YT0|A PF00641.13_zf-RanBP_seed 24 34 !Q:0,4|7,9|13,15|18,18|21,21|24,24|28,29|31,33 Q:5,6|10,12|16,17|19,20|22,23|25,27|30,30 ???-?EE?--TTT?-?EE?SS?SB?TTT??B??? 1N0Z|A PF00642.19_zf-CCCH_seed 88 29 !Q:0,1|3,5|13,16|22,22|25,25 Q:2,2|6,12|17,21|23,24|26,28 ??S???SGGGGTS--??TTTTT?SS?SSS 2RHK|C PF00643.19_zf-B_box_seed 106 71 !Q:0,0|5,7|11,18|20,24|33,33|36,36|44,49|52,53|56,61|63,63|65,67|69,70 Q:1,4|8,10|19,19|25,32|34,35|37,43|50,51|54,55|62,62|64,64|68,68 ?TTSB?--TTT?-----?-B---??EEETTTTE-EE?HHHHHSH------HH--HS------S?E---E?? 2EGM|A PF00644.15_PARP_seed 28 280 !Q:1,1|3,3|8,9|26,27|33,35|61,67|70,84|92,93|104,104|106,109|113,113|119,123|125,125|139,140|144,148|151,157|159,164|168,173|181,182|184,184|191,197|200,201|204,205|210,210|216,220|224,226|233,235|238,241|243,243|246,246|248,249|251,251|253,255|259,259|265,265 Q:0,0|2,2|4,7|10,25|28,32|36,60|68,69|85,91|94,103|105,105|110,112|114,118|124,124|126,138|141,143|149,150|158,158|165,167|174,180|183,183|185,190|198,199|202,203|206,209|211,215|221,223|227,232|236,237|242,242|244,245|247,247|250,250|252,252|256,258|260,264|266,279 T?E-EEEE??TTSHHHHHHHHHHHHT??GGGTT---EEEEEEEEEEEEETTHHHHHGGGGG-------SS?--------------EEEEEEE??GGGHHHHHHH?S????TTS?GGGST-----T?SSEEEBSSHHHHH--GGG??--?SS-------S?-----EEE------EEEEEEE??S-EEEESS???-?--SS??TT??EEEE?EEEEE?----TTS?--EEETTE---EE????E-EE?S??S?S---EEE?EEEES?GGGEEEEEEEEEEE 4HKK|A PF00645.13_zf-PARP_seed 54 118 !Q:2,3|6,6|9,9|11,13|17,20|23,23|26,26|35,35|38,45|48,49|52,53|55,56|68,68|72,73|75,80|87,88|93,97|99,101|108,111 Q:0,1|4,5|7,8|10,10|14,16|21,22|24,25|27,34|36,37|46,47|50,51|54,54|57,67|69,71|74,74|81,86|89,92|98,98|102,107|112,117 EE??SS?EE?T---TSS---?EE?TT?EEEEEEEE?TT?-------SS??EE??B??HHHHHHHHHHS?SSS??S-----?TTSSSB--STTT-----S?--HHHHHH----HHHHHH 3OD8|A PF00646.28_F-box_seed 463 81 !Q:6,6|9,32|42,42|46,54|62,62|71,71 Q:0,5|7,8|33,41|43,45|55,61|63,70|72,80 SHHHHS?HH------------------------HHHHHHTTS?HHH---------HHHHTTS?HHHHHHHT?HHHHHHHHH 3L2O|B PF00647.14_EF1G_seed 40 135 !Q:0,4|8,9|12,18|20,21|33,33|35,36|40,41|50,53|57,57|63,64|66,68|72,77|90,90|94,95|97,97|106,107|112,112|114,114|117,117|127,131 Q:5,7|10,11|19,19|22,32|34,34|37,39|42,49|54,56|58,62|65,65|69,71|78,89|91,93|96,96|98,105|108,111|113,113|115,116|118,126|132,134 -??-?GGG--SS??---??S?-HHHHHHHHHHS?G--GGT--HHHHHHSS-??-TTT?EEEEE??S--?GGG?--??-STTHHHHHHHHH-HHG--G-GTGGGEEE??EEES?S-TT?EEEEEEEES-----SSS 1PBU|A PF00648.16_Peptidase_C2_seed 9 371 !Q:0,3|7,7|14,14|19,19|22,22|28,28|32,32|37,37|40,40|43,43|48,54|57,60|62,62|64,65|68,69|91,91|94,95|100,102|123,123|127,127|132,133|137,137|139,139|145,145|165,165|167,167|170,170|173,175|180,180|189,190|192,226|231,232|242,255|261,263|267,267|272,272|274,274|278,278|282,283|295,298|310,310|314,319|326,326|333,333|341,343|345,346|361,362|368,370 Q:4,6|8,13|15,18|20,21|23,27|29,31|33,36|38,39|41,42|44,47|55,56|61,61|63,63|66,67|70,90|92,93|96,99|103,122|124,126|128,131|134,136|138,138|140,144|146,164|166,166|168,169|171,172|176,179|181,188|191,191|227,230|233,241|256,260|264,266|268,271|273,273|275,277|279,281|284,294|299,309|311,313|320,325|327,332|334,340|344,344|347,360|363,367 ????TTS?SSHHHH?SSTT?TT?SSSTT?EEE?HHHH?SS?BS?SSSS?------GG----G?B??SS??HHHHHHHHHHHTSHHHHHHHS?TT??SSTT-??SEEEEEEEETTEEEEEEEES?EEE-ETTE--ESS?B?SSTTB?HHHHHHHHHHHHTTSSGGG?S?SS?TT???SSSS?EEEEEGGG??T-----------------------------------THHH--HHHHHHHTT?-------------EEEEE???SSS-TTTT?B?TTS?BTT??EEEEEEEEEEE----TTEEEEEEEEE?TTS-?????STTSTT?GGGGGB?HHHHHHH???S?-SSEEEEEHHHHHHH??EEEEE??? 1U5I|A PF00649.13_Copper-fist_seed 23 49 !Q:0,1|20,22|26,30|33,33|36,39|42,42|44,47 Q:2,19|23,25|31,32|34,35|40,41|43,43|48,48 ?-EEETTEEEEETTTTTTSG---GGG????-SS?EE----EE?S????S 1CO4|A PF00650.15_CRAL_TRIO_seed 110 240 !Q:6,6|14,15|19,19|25,25|28,28|30,31|33,37|39,39|41,65|81,97|99,100|102,109|111,113|120,123|125,125|128,140|143,143|152,152|158,158|167,168|180,181|185,186|197,197|199,212|218,220|227,233|237,238 Q:0,5|7,13|16,18|20,24|26,27|29,29|32,32|38,38|40,40|66,80|98,98|101,101|110,110|114,119|124,124|126,127|141,142|144,151|153,157|159,166|169,179|182,184|187,196|198,198|213,217|221,226|234,236|239,239 GGGGTT?SEEEEEE-?TTS?EEEEE?GG-G??S?----S?H-------------------------HHHHHHHHHHHHHHH-----------------T??T--------T???EEEEEE????T-TS?????????????SH-HHHHHHHH-HHSTT?EEEEEEES??HHHHHHHHHHG--GGB-?HHHHTTEEES-S?-------------GGGTS?--GGGSBG-------GGT-?S 3HY5|A PF00651.26_BTB_seed 96 157 !Q:8,10|12,13|20,25|32,32|40,40|49,81|85,86|89,89|92,93|103,104|112,124|136,136|141,141|153,156 Q:0,7|11,11|14,19|26,31|33,39|41,48|82,84|87,88|90,91|94,102|105,111|125,135|137,140|142,152 HHHHHHHT--?S??EEEEET------TEEEEE?HHHHHHH?HHHHHHHT??--------------???????----------EEE??SS?HH--HHHHHHHHH--HHSEEEE?------------TTTHHHHHHHH-HHHT?HHHHHHHHHHH???? 1R28|A PF00652.17_Ricin_B_lectin_seed 97 197 !Q:3,4|9,10|12,13|17,17|19,20|23,25|28,28|30,30|34,36|38,44|47,48|50,50|52,54|57,57|60,65|67,67|75,83|89,89|92,103|106,106|113,117|120,126|128,128|132,132|134,141|144,144|150,150|152,155|163,167|171,171|177,190|193,193|195,195|197,197 Q:0,2|5,8|11,11|14,16|18,18|21,22|26,27|29,29|31,33|37,37|45,46|49,49|51,51|55,56|58,59|66,66|68,74|84,88|90,91|104,105|107,112|118,119|127,127|129,131|133,133|142,143|145,149|151,151|156,162|168,170|172,176|191,192|194,194|196,196 SSB??EETT--T??EEE?G--GG???TT?B?EEE???S------?GG--G?B---EE?TT------S?EEETTTE---------EEEES?SS------------TT?BEEEEE???-?GG-------G?EEE?T--------TS?EEETT-T?--?EEEEGGG??---STT?BEEEE-??----???----GG-G?E- 2ZQN|A PF00653.16_BIR_seed 184 134 !Q:5,5|7,7|9,36|43,43|46,48|50,50|59,59|62,77|80,80|87,88|91,94|97,99|102,109|118,118|120,123|125,126|128,130 Q:0,4|6,6|8,8|37,42|44,45|49,49|51,58|60,61|78,79|81,86|89,90|95,96|100,101|110,117|119,119|124,124|127,127|131,133 HHHGG-G-G-----------------------??---GGGTTS?HH---H-HHHTTEEE?SS----------------TT?EEETTT??EE----ES?-?TT?------?HHHHHHHH?T----T-?H---HHH 3D9T|A PF00654.15_Voltage_CLC_seed 139 730 !Q:6,12|20,21|25,27|29,31|33,34|44,46|49,49|51,59|72,73|81,81|83,83|101,102|104,114|117,122|125,128|132,132|152,152|163,175|177,177|180,181|185,200|219,226|228,228|230,233|235,273|290,290|304,304|306,310|319,319|323,335|346,348|351,354|359,362|366,388|390,390|392,393|397,397|400,406|409,513|519,521|524,575|577,577|600,600|618,618|621,625|627,627|634,658|661,667|670,671|673,676|693,694|707,709 Q:0,5|13,19|22,24|28,28|32,32|35,43|47,48|50,50|60,71|74,80|82,82|84,100|103,103|115,116|123,124|129,131|133,151|153,162|176,176|178,179|182,184|201,218|227,227|229,229|234,234|274,289|291,303|305,305|311,318|320,322|336,345|349,350|355,358|363,365|389,389|391,391|394,396|398,399|407,408|514,518|522,523|576,576|578,599|601,617|619,620|626,626|628,633|659,660|668,669|672,672|677,692|695,706|710,729 HHHHHH-------HHHHHHH-?GGG---S---S-?SHHHHHHHH---TT?S?-?-----?HHHHHHHHHHHH--HHHHHTT?S?BTHHHHHHHHHHHHHHH--H-----------HT------TT?--?SHH-HHHHHHHHHHHHHHHHHHT?HHHHHHHHHH-------------T-TS-?SSS???-------??----HHHHHHHHHHHHHHHHHH--------H?S?--?S-----------??-----?????----------?---??GGGHHHHHHHHHHHHH-HHHHHHHHHHHHH-H-----HHHHHHTT?HHH-------------HHHHHHHHHH---HH----HHHH----HHS-----------------------G-G--GSS?ST-------TH---------------------------------------------------------------------------------------------------------HHHHH---HT?---------------------------------------------------S?HHHHHHHHHHHHHHHHHHHHTT?SSBSHHHHHHHHHHHHH-HH-----H-HHHHHH------------------------?GG-------GT??T----HHHHHHHHTTHHHHTT??HHHHHHHHHHHH?-?GGGHHHHHHHHHHHHHHHHT 4FG6|A PF00656.17_Peptidase_C14_seed 115 664 !Q:7,11|15,26|41,41|45,45|47,51|57,66|68,68|71,154|162,162|168,168|171,175|180,182|191,191|193,194|197,204|209,209|211,223|227,229|231,233|238,253|263,263|270,270|272,272|279,279|284,284|286,521|523,523|526,526|535,535|539,541|544,560|576,576|583,589|591,591|607,622|626,641|646,646|648,650|653,653|656,657|661,662 Q:0,6|12,14|27,40|42,44|46,46|52,56|67,67|69,70|155,161|163,167|169,170|176,179|183,190|192,192|195,196|205,208|210,210|224,226|230,230|234,237|254,262|264,269|271,271|273,278|280,283|285,285|522,522|524,525|527,534|536,538|542,543|561,575|577,582|590,590|592,606|623,625|642,645|647,647|651,652|654,655|658,660|663,663 EEEEEEE?????GGG-------?????TTHHHHHHHHHHHH-HHH-T-----EEEEE----------E-ES----------------------------------------------------------------------------------??HHHHHHH-HHHHT-TS??---TTEE---EEEEEEES?E--ET--------TEEE?S-------------SSE---E---EHHH----------------HHHTTSTTT?GGGTTS?E-EEEEES?SSSB?B??????????------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------??????????B?TT?SEEEEESS?TTB???EE-----------------TTTEEHHHHHHHHHH-HHHTTT-------S?HHHHHHHHHHHHHHS?----------????-SSG----------------GGTT?B???EE-EE??SSB??S 3D6F|A PF00657.17_Lipase_GDSL_seed 65 494 !Q:13,25|27,28|32,37|47,72|83,83|86,87|90,168|171,174|185,192|200,201|207,246|252,254|271,271|275,275|281,286|291,318|322,322|330,333|349,371|376,377|380,380|396,465|472,479|482,482 Q:0,12|26,26|29,31|38,46|73,82|84,85|88,89|169,170|175,184|193,199|202,206|247,251|255,270|272,274|276,280|287,290|319,321|323,329|334,348|372,375|378,379|381,395|466,471|480,481|483,493 EEEEESHHHHTTT?------------S??STT??????HHHHHHHHT--------------------------TTTEEEEEEE?TT??HH-------------------------------------------------------------------------------HH----HHHHHHHHHH-----???EEEEEEE??TTTTS----------------------------------------SSSTT???HHHHHHHHHHHHHHHH-HTT?EEEEE??????HHHH----------------------------HHH?HHHHHTT????HHHHHHHHHHHHHHH-----------------------HHTT??EE?HHHHHHHHHGGGGGG----------------------------------------------------------------------GBSSSS--------SB?HHHHHHHHHHH 2WAB|A PF00658.13_PABP_seed 38 93 !Q:0,2|10,10|15,21|35,38|40,47|52,53|55,56|77,77 Q:3,9|11,14|22,34|39,39|48,51|54,54|57,76|78,92 ???SHHHHTT?TTTT-------TTTTTTSSSHHHH----H--------HHTT--S??SSHHHHTTTSSSHHHHHHHH?TTHHHHHHHHHHHHH 2DYD|A PF00659.13_POLO_box_seed 81 99 !Q:2,2|14,14|29,29|35,37|43,47|49,64|66,67|80,87 Q:0,1|3,13|15,28|30,34|38,42|48,48|65,65|68,79|88,98 EE?SSEEEEEETTS?EEEEETTTTEEEEE-ETTTT---EEEEE?----T----------------T??EEEEEHHHHHHH?----?-?HHHHHHHHHHH 3P36|A PF00661.16_Matrix_seed 13 355 !Q:0,12|25,35|43,43|47,48|64,83|99,99|101,101|112,112|133,134|158,158|163,163|167,167|181,181|183,189|195,197|212,214|226,226|229,229|232,233|247,247|252,254|266,266|286,288|296,296|309,309|320,320|342,343|349,349|352,354 Q:13,24|36,42|44,46|49,63|84,98|100,100|102,111|113,132|135,157|159,162|164,166|168,180|182,182|190,194|198,211|215,225|227,228|230,231|234,246|248,251|255,265|267,285|289,295|297,308|310,319|321,341|344,348|350,351 ?????????????GGGGGGTTSSSS???????????EEEEEES?TTS??TTSEEEEEEEEEEEE????????????---?????EEEEEEEEEEEEEES?S?HHHHHHHHHH?EEEEEEEESSSEEEEEEEEE??GGGTTSHHHHHTEEEEEHHHHBS?GGGS?SSS?EEEEEEEEEEEEE?S???????TTGGG???TTEEEEEEEEEEEE???TTSGGGGGSEE?SS?EE--EEEEEEEEEEESS?SSSS???HHHHHHHHHHH?EEEEEEESSSEEEEEEESS???TTTGGGS?TTSEEEEEHHHH?HHHHHHHHHS?EEEEEEEEEEEESSHHHHHHS??EEEEE?EE??? 4G1L|A PF00662.15_Oxidored_q1_N_seed 32 71 !Q:9,9|12,13|22,22|49,49|51,51|53,53|56,62 Q:0,8|10,11|14,21|23,48|50,50|52,52|54,55|63,70 EEEEEEEEE?SS-?EEEEEEEE?HHHHHHHHHHHHHHHHHHHHHHHHTS-S?S?HH-------HHHHHHHH 4HEA|L PF00664.18_ABC_membrane_seed 70 377 !Q:17,19|41,41|44,44|53,64|81,102|110,111|120,120|141,141|145,145|150,151|156,165|185,185|194,194|208,210|214,215|238,238|253,261|265,265|269,272|276,280|288,291|304,304|322,322|333,333|342,343|346,348|355,357|360,360|363,363 Q:0,16|20,40|42,43|45,52|65,80|103,109|112,119|121,140|142,144|146,149|152,155|166,184|186,193|195,207|211,213|216,237|239,252|262,264|266,268|273,275|281,287|292,303|305,321|323,332|334,341|344,345|349,354|358,359|361,362|364,376 HHHHHHHHHHHHHHHHH---HHHHHHHHHHHHHHHHHHHHH?SS?SHHHHHHH------------HHHHHHHHHHHHHHHH----------------------HHHHHHH--HHHHHHHH-HHHHHHHHHHHHHHHHHHHH-HTT-STTH--HHHS--------??SHHHHHHHHHHHHHHHHHH-HHHHHHHH-HHHHHHHHHHHHH---HHT--TSSSHHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHH---------HHH-HHH----TTT?????HHHHHTT????SHHHHHHHHHHH-HHHHHHTTTHHHHHHHH-HHHHHHHHHH-HHHHHHHH--HH---HHHSSS?--SS?HH-HHHHHHHHHHHHH 4A82|A PF00665.21_rve_seed 230 190 !Q:0,1|14,18|20,21|25,55|57,57|68,69|79,87|97,97|103,120|126,126|128,128|135,149|160,162|167,168|171,171 Q:2,13|19,19|22,24|56,56|58,67|70,78|88,96|98,102|121,125|127,127|129,134|150,159|163,166|169,170|172,189 ??SSTTSEEEEEEE--???S-?BTT-------------------------------B?EEEEEEETTT??EEEEEESSS--------?HHHHHHHHH-HHHTT??---------------?SEEEE?S?HHHHSH---------------HHHHHHHTTT--?EEEE??TT?GGGGHHHHHHHHHHHHHH 4E7K|A PF00666.12_Cathelicidins_seed 8 68 !Q:0,0|18,19|30,43|59,60|62,62|67,67 Q:1,17|20,29|44,58|61,61|63,66 ?HHHHHHHHHHHHHHHHH??SSEEEEEEEE???-??????????EEEEEEEEEEEEESS??S?GGGS? 1KWI|A PF00667.15_FAD_binding_1_seed 15 242 !Q:6,7|18,18|20,20|23,23|26,26|34,34|37,37|39,41|44,46|49,49|54,58|69,69|72,75|77,77|79,79|88,90|94,95|101,102|105,105|108,108|118,119|122,125|137,138|151,155|167,169|181,183|186,186|193,193|195,197|203,203|205,205|219,220|227,228|232,232|236,236 Q:0,5|8,17|19,19|21,22|24,25|27,33|35,36|38,38|42,43|47,48|50,53|59,68|70,71|76,76|78,78|80,87|91,93|96,100|103,104|106,107|109,117|120,121|126,136|139,150|156,166|170,180|184,185|187,192|194,194|198,202|204,204|206,218|221,226|229,231|233,235|237,241 HHHTTS??EEEEEEEEEE?S?TT?SS?EEEEEEE?TT?G---GG???TT?EEEE?????HHHHHHHHTT?SS???-S?S?EEEEEEEE???SSS??EEEEE??SS?SB?HHHHHHHTB??SS-???HHHHHHHHTTB??HHHHHHHHHHTT?----SHHHHHHHHHH???HHHHHHHSTTB???HH-HHHHHS?B???EEEEB?S?TTTSTTEEEEEEE??EEETGG--GTS?EEE?HHHHH 1DDI|A PF00668.15_Condensation_seed 42 355 !Q:0,1|6,7|21,22|25,29|33,34|42,46|61,61|74,77|84,84|86,91|96,107|118,119|121,125|130,132|144,144|152,154|160,161|179,191|193,206|237,250|253,255|258,260|264,267|273,274|277,279|293,294|313,313|315,315|317,317|324,327|329,333|339,340|342,344|352,354 Q:2,5|8,20|23,24|30,32|35,41|47,60|62,73|78,83|85,85|92,95|108,117|120,120|126,129|133,143|145,151|155,159|162,178|192,192|207,236|251,252|256,257|261,263|268,272|275,276|280,292|295,312|314,314|316,316|318,323|328,328|334,338|341,341|345,351 ??SSEE??HHHHHHHHHHHHT??TT-----TTB??EEEEEEE--???HHHHHHHHHHHHHH?GGGGEEEEEETT----EEEEEE?S??????EEEE??----------HHHHHHHHHH--T?????TTSS-??EEEEEEEEETT-EEEEEEE---EBGGG??HHHHHHHHHHHHHHHTT??-------????S------------??HHHHHHHHHHHTTSHHHHHHHHHHHHHTSS????-----?????SS???SS???BEE----EEEEE??HH---HHHHHHHHHHHHT??HHHHHHHHHHHHHHHHHT?S?E-EEEEEE????S-----GGGTT??S???EEEEEEE??? 1Q9J|A PF00669.15_Flagellin_N_seed 34 152 !Q:31,32|37,37|76,77|89,97|107,107|110,111|114,115|138,139|144,144|149,149 Q:0,30|33,36|38,75|78,88|98,106|108,109|112,113|116,137|140,143|145,148|150,151 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS??TTTS?SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--HHHHHHHHHHH---------HHHHHHHHT?TT??HH--HHHHHHHHHHHHHHHHHHHHHH??BTTB?TTTS?EE 3PWX|A PF00670.16_AdoHcyase_NAD_seed 16 164 !Q:17,20|23,23|29,30|46,46|52,52|54,54|66,66|69,70|78,78|84,85|89,89|92,92|100,100|108,108|113,113|116,116|124,124|143,143|145,145|162,163 Q:0,16|21,22|24,28|31,45|47,51|53,53|55,65|67,68|71,77|79,83|86,88|90,91|93,99|101,107|109,112|114,115|117,123|125,142|144,144|146,161 HHHHHHHHHHHHHHHHH????TT?EEEEE??SHHHHHHHHHHHTTT?EEEEE?S?HHHHHHHHHTT?EE??HHHHTTT?SEEEE??SSS?SB?HHHHTTS?TTEEEEE?SSSS?SB?HHHHHHH-EEEEEEEETTEEEEEETT-S?EEEEEGGGSBHHHHHS?? 3CE6|A PF00672.20_HAMP_seed 222 106 !Q:2,2|16,105 Q:0,1|3,15 HH-HHHHHHHHHHHHH??????????????????????-?-?-----------?---??---?-------------???--???-????????????????????? 2F95|B PF00673.16_Ribosomal_L5_C_seed 133 133 !Q:4,4|9,10|20,20|33,35|37,37|40,40|42,42|46,46|53,54|56,56|63,66|68,70|75,80|87,101|104,104|109,118|129,130|132,132 Q:0,3|5,8|11,19|21,32|36,36|38,39|41,41|43,45|47,52|55,55|57,62|67,67|71,74|81,86|102,103|105,108|119,128|131,131 EEEE-EEEE?-HHHHHHHHH-HHHHTTGGGSTT???B?SS?B?SSS-EEEEEE--S?GGGSTT??--G---GGSS?--???EEEEEE---------------ES?SSHH----------HHHHHHHHHT??B? 2ZJQ|D PF00675.15_Peptidase_M16_seed 26 167 !Q:6,6|9,9|20,20|25,26|44,44|48,48|51,51|63,63|66,69|74,74|89,94|110,115|125,125|137,137|139,140|161,161|164,165 Q:0,5|7,8|10,19|21,24|27,43|45,47|49,50|52,62|64,65|70,73|75,88|95,109|116,124|126,136|138,138|141,160|162,163|166,166 EEEEEE?SS?SEEEEEEEEE?SGGG??TTTTTHHHHHHHHTTSB-BSS?BH-HHHHHHHHHTT?EE----EEEE?SSEEEEEEEEEGGG------HHHHHHHHHHHHHSB---???HHHHHHHHH-HHHHHHHHHTT?H--HHHHHHHHHHHHTTTSGGGS?SS??H 1SQB|A PF00676.15_E1_dh_seed 16 332 !Q:22,22|24,28|31,31|43,43|46,46|51,54|56,57|62,62|67,70|81,81|94,100|104,106|108,112|118,119|125,126|134,143|148,150|160,160|163,163|178,179|181,183|190,190|197,197|203,203|205,207|211,212|218,218|226,226|245,247|254,256|259,259|264,266|268,268|272,272|284,284|300,300|326,329 Q:0,21|23,23|29,30|32,42|44,45|47,50|55,55|58,61|63,66|71,80|82,93|101,103|107,107|113,117|120,124|127,133|144,147|151,159|161,162|164,177|180,180|184,189|191,196|198,202|204,204|208,210|213,217|219,225|227,244|248,253|257,258|260,263|267,267|269,271|273,283|285,299|301,325|330,331 HHHHHHHHHHHHHHHHHHTTSS?S?????TT?HHHHHHHHHHS?TT-SEEE??--S??HHHH-HHTT??--HHHHHHHHTT?TTSTTTTSSGGG?--??--BTT---B?????STTTH--HHHHH--HHHHHHH----------HHTS???EEEEEETTG-GG?HHHHHHHHHHHHHT??E---EEEEEE?SEETTE-EHHHH?S???GGG--TTTTS?EEEEETT?HHHHHHHHHHHHHHHHTT???EEEEEE???SS?SSTT-??S?SSS?HHHHHHHHHHH?HHHHHHHHHHHTTSS?HHHHHHHHHHHHHHHHHHHHHHHHS????GG 2BEU|A PF00677.12_Lum_binding_seed 20 97 !Q:0,4|16,21|33,33|40,41|44,44|55,56|59,63|72,72|78,78|85,86|89,89|96,97 Q:5,15|22,32|34,39|42,43|45,54|57,58|64,71|73,77|79,84|87,88|90,95 ?????EEEEEEEEEEE------TTEEEEEEEES?GGGGGG??TT?EEEETTEEEE??SB?----SSEEEEEE?HHHHH-HSSGGG??TT?EEEEEE?- 1PKV|A PF00679.19_EFG_C_seed 172 113 !Q:13,18|32,32|35,37|45,53|56,61|74,74|76,76|78,78|86,87|90,90|97,98|104,105|112,112 Q:0,12|19,31|33,34|38,44|54,55|62,73|75,75|77,77|79,85|88,89|91,96|99,103|106,111 EEEEEEEEEEEEE?-----SSTHHHHHHHHHH-TT?-?EEEEEEE---------TT------EEEEEEEEEGGG?T-T?HHHHHHH??SS?EEEEEE--EEEEE??HHHHTT? 1N0V|C PF00680.15_RdRP_1_seed 39 693 !Q:1,4|15,22|32,32|41,41|52,54|56,56|60,60|62,62|65,67|69,69|74,74|81,81|84,88|91,91|100,101|104,104|124,128|135,138|142,145|171,171|180,182|184,184|194,196|200,200|204,205|209,211|215,215|222,222|228,228|232,232|234,234|236,236|244,269|272,277|288,289|316,318|330,340|355,356|372,376|389,390|394,395|400,402|407,407|411,417|419,419|421,422|449,449|456,456|473,473|478,483|487,487|497,497|518,518|520,520|524,524|528,528|531,531|540,543|546,547|549,549|552,552|557,557|567,568|570,570|573,575|578,578|580,580|588,588|593,594|604,612|635,635|641,642|657,657|661,661|664,665|669,670|679,679|687,688 Q:0,0|5,14|23,31|33,40|42,51|55,55|57,59|61,61|63,64|68,68|70,73|75,80|82,83|89,90|92,99|102,103|105,123|129,134|139,141|146,170|172,179|183,183|185,193|197,199|201,203|206,208|212,214|216,221|223,227|229,231|233,233|235,235|237,243|270,271|278,287|290,315|319,329|341,354|357,371|377,388|391,393|396,399|403,406|408,410|418,418|420,420|423,448|450,455|457,472|474,477|484,486|488,496|498,517|519,519|521,523|525,527|529,530|532,539|544,545|548,548|550,551|553,556|558,566|569,569|571,572|576,577|579,579|581,587|589,592|595,603|613,634|636,640|643,656|658,660|662,663|666,668|671,678|680,686|689,692 S---?SSHHHHHHHH????????EEETTEETT?HHHHHHHH-HHHHHHHHHS???B?TTS?B?TT???S?SGGG?EEEEEE?BS?????SB?HHHHHHTT??SS?SSHHHHHHHHHHHHHHHSS?????EEEETT????TTT????HHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHH???S?EEEEEEEES???EEE?TTT??EEE???EEE?HHHHHT-TTSSS?EEE?B?B?THHHHHH-------????--------------?TT-----?EEEEEEEEEE??HHHHHHHHHHHHHHHHHHHHTTHHHH???SHHHHHHHHHT----------?SEEEEEEESSHHHH??HHHHHHHHHHHHHHT??---HHHHHHHHHHTS??EEE??SSTT???EEES?TTS----???B?S??TTSTTHHHHHHHHHHHHHHHHHHHHT?GGGGGG?SSHHHHHHHHHHHHTT?SSEE------EEE-ETTEEEEEE?SSSHHHHHHHHHHHHHHTSS?S?SSS?EEE?SS?EETTEEEE?--?TT??G-GG?EEEE?HHHHHHHHH--S?SS???TT?S?GGGSSSS?GGGH--HHHHHHHHT---------TSTTHHHHHHHHHHHHHHHHSS?HHHHH--HHHHHHHHHHHTTT?TTS?TT??GGG??HHHHHHHH?GGGGGTT??GGGS 2E9T|A PF00681.15_Plectin_seed 119 47 !Q:11,11|15,16|20,21|24,24|35,35|47,47 Q:0,10|12,14|17,19|22,23|25,34|36,46 HHHHHHHHTTT-SEE?-TTT??EE?HHHHHHTTSS?HHHHHHHHHHH- 1LM7|A PF00682.14_HMGL-like_seed 20 293 !Q:1,12|28,28|35,48|52,52|66,67|69,71|80,92|108,108|119,119|129,131|150,150|152,152|154,163|174,174|189,194|196,197|203,203|207,209|224,224|236,236|238,238|242,242|255,256|265,272|276,276|278,278|281,281 Q:0,0|13,27|29,34|49,51|53,65|68,68|72,79|93,107|109,118|120,128|132,149|151,151|153,153|164,173|175,188|195,195|198,202|204,206|210,223|225,235|237,237|239,241|243,254|257,264|273,275|277,277|279,280|282,292 T?????????-??HHHHHHHHHHHHHHT?SEEEEE-------------?GGG?HHHHHHHHHHHHH??S---SEEEEEEE-------------SSHHHHHHHHHHHTT?SSEEEEEEEE?SHHHHHHTT???HHHHHHHHHHHHHHHHTT?S?E----------EEEEETGGGS?HHHHHHHHHHHHHT------T??EEEEE?SSS???HHHHHHHHHHHHHH?TTGGGSEEEEE?B?TTS?HHHHHHHHHHTT??EEEEBGGG??------TTT?B?BH-HHHHHHHHHTH 3HO8|A PF00683.12_TB_seed 34 53 !Q:2,2|4,4|7,8|10,11|17,17|22,23|25,28|34,34|40,42|45,45 Q:0,1|3,3|5,6|9,9|12,16|18,21|24,24|29,33|35,39|43,44|46,52 TT?B?SS??E--EEHHH-HHHT??S----EEEET-TEEEE???SS-SHHHHHH 1APJ|A PF00684.14_DnaJ_CXXCXGXG_seed 63 76 !Q:0,0|9,13|17,18|20,20|22,22|36,41|50,50|60,64|68,68 Q:1,8|14,16|19,19|21,21|23,35|42,49|51,59|65,67|69,75 ?GGGTTTSB?----SSS??E-E?TTTTTSSEEEEEE------TTEEEEEE?TTTTTSSEE--?--SSB?GGGTTSS 1EXK|A PF00685.22_Sulfotransfer_1_seed 45 409 !Q:2,2|23,37|41,41|45,48|51,65|69,145|153,154|157,158|162,163|165,167|172,172|180,180|187,188|203,203|205,217|220,223|225,226|229,238|247,260|262,262|266,267|278,279|285,285|297,297|311,319|330,371|374,376|381,381|383,383|395,401|404,406 Q:0,1|3,22|38,40|42,44|49,50|66,68|146,152|155,156|159,161|164,164|168,171|173,179|181,186|189,202|204,204|218,219|224,224|227,228|239,246|261,261|263,265|268,277|280,284|286,296|298,310|320,329|372,373|377,380|382,382|384,394|402,403|407,408 TT?EEEEESTTSSHHHHHHHHHH---------------HHH?SSS----TT??????----?????BTT??-----------?----------------------------------------------------------?????HHHHHHT??SS?-EEE--E???GGGS?THHHHTT?EEEEEE??HHHHHHHHHHHHHH?T-------------TS????S--HH----------HHHHHHHT--------------T?SBT??HHHHHHHHHH--HTTTS?EEEEEHHHHHH?HHHHHHHHHHHTT????-----TTHHHHHHHH??????????????????????------??????????????GG---GGTS?H-HHHHHHHHHHH-------HH???TT 1ZRH|A PF00686.14_CBM_20_seed 101 129 !Q:4,4|11,19|22,22|37,37|39,39|42,42|44,44|46,46|48,48|51,53|56,56|59,59|63,64|67,67|72,72|74,78|87,91|93,94|97,101|103,103|106,109|111,111|113,113|118,119|123,123 Q:0,3|5,10|20,21|23,36|38,38|40,41|43,43|45,45|47,47|49,50|54,55|57,58|60,62|65,66|68,71|73,73|79,86|92,92|95,96|102,102|104,105|110,110|112,112|114,117|120,122|124,128 EEEE-EEEEES?-----???TT?EEEEEESSGGGTTT?G-GG?B?S?B?SS---SS?TT?EEE--EE-EEET-T?----EEEEEEEE-----E-?SS----?E-EE??--S-S?EEEE??SSS?EEEEE 8CGT|A PF00687.16_Ribosomal_L1_seed 255 398 !Q:6,10|12,59|62,64|66,67|70,73|75,85|91,330|332,345|348,348|368,368|370,376|380,380|382,383|385,386|390,392|396,396 Q:0,5|11,11|60,61|65,65|68,69|74,74|86,90|331,331|346,347|349,367|369,369|377,379|381,381|384,384|387,389|393,395|397,397 HHHTTT-----T---------------------------------------------?--SS???S??EE????S?--------??SSGGG??-----------????????-???------------????-?-----------????-???-???-----------------------????????-??????????--------??-???----?????????????????-?--?????----???????????----?????-------------------------------------?---??????????????????----?S?--?????????--SS-SHHHHHHHHHHHHHHHHHS?S?----??SSS-S-?S??EEE--?SSS?E 1S1I|A PF00688.13_TGFb_propeptide_seed 81 403 !Q:0,37|40,42|48,51|73,73|75,76|78,83|85,94|98,99|101,106|110,110|112,112|120,133|135,136|139,158|161,179|187,189|196,198|202,204|213,213|227,228|232,232|238,255|258,259|268,279|283,283|292,294|296,298|300,302|304,305|311,311|315,315|319,320|324,326|328,330|333,337|343,343|346,349|355,355|363,372|375,391|396,396 Q:38,39|43,47|52,72|74,74|77,77|84,84|95,97|100,100|107,109|111,111|113,119|134,134|137,138|159,160|180,186|190,195|199,201|205,212|214,226|229,231|233,237|256,257|260,267|280,282|284,291|295,295|299,299|303,303|306,310|312,314|316,318|321,323|327,327|331,332|338,342|344,345|350,354|356,362|373,374|392,395|397,402 ??------------------------------------HH---HHHHH----HHHHHHHHHHHHHHHHHHHHT?S--S?---??T----------TSS??S???---HHH-H-HHHHHHH--------------S??EE????--------????????SS------------------?EEEEEEE???SSTTTT---TTT???TTEEEEEE?HHHHHHHSSSTTT??EEE-EEEEB----------------??TT??EEEEEEEE-----------?SSS?EEEEEEEE---E???S---S??EEEEE?HHH-HHH--HHH???S--?EE-----EEEEE?EE----EEEET-TEEEEEE??????????SB??---------------SSSS?SEEEEE 3RJR|A PF00689.16_Cation_ATPase_C_seed 141 381 !Q:0,4|20,20|27,34|41,46|49,50|53,53|61,61|75,77|80,80|85,128|131,137|142,144|151,151|153,172|174,175|182,183|186,199|216,216|223,226|229,244|248,248|250,250|253,254|257,258|261,265|275,275|285,285|288,296|301,301|303,335|341,349|353,357|368,369|374,377 Q:5,19|21,26|35,40|47,48|51,52|54,60|62,74|78,79|81,84|129,130|138,141|145,150|152,152|173,173|176,181|184,185|200,215|217,222|227,228|245,247|249,249|251,252|255,256|259,260|266,274|276,284|286,287|297,300|302,302|336,340|350,352|358,367|370,373|378,380 ?????HHHHHHHHHHHSSHH-HHGGGG???-?---TTGGGS-???-?SS??SS?HHHHHHH-HHHHHHHHTSSSH---HH-HHHH--------------------------------------------TT-------SSSS???TTTTTS?S?????----------?????S??SSSGGG-?SH--------------HHHHHHHHHHHHHHHH-HGGGSS----SS?--------------?TTT-S?GG--GS--HH-----HHHHHHHHH-HHHHHHHHS-TT---------TGGG-S-???----??-----------------------TTTHH---------HHH-----HHHHTHHHHH--HHHH----HHH 3W5C|A PF00690.21_Cation_ATPase_N_seed 168 94 !Q:0,0|4,4|13,19|21,23|25,30|33,36|38,41|49,52|56,57|59,60|62,62|66,69|74,76|78,79 Q:1,3|5,12|20,20|24,24|31,32|37,37|42,48|53,55|58,58|61,61|63,65|70,73|77,77|80,93 ?SSS?HHHHHHHH-------T-??T------TT??-?H----HHHHHHH----HHH??S??T-TTT????TTTT???S-?SHHHHHHHHHHHHH 3W5C|A PF00691.15_OmpA_seed 84 189 !Q:1,2|5,19|28,31|35,36|41,48|50,50|53,56|58,60|66,89|91,99|101,105|109,112|128,128|134,141|144,146|149,150|153,154|157,157|160,161|164,164|167,167|173,173|179,187 Q:0,0|3,4|20,27|32,34|37,40|49,49|51,52|57,57|61,65|90,90|100,100|106,108|113,127|129,133|142,143|147,148|151,152|155,156|158,159|162,163|165,166|168,172|174,178|188,188 E??TT???-?--?-------GGGHHHHH----HHH--HHHH--------H?TT---?E---EEEEE?---------------------??S--------?S?----HHH----HHHHHHHHHHHHHHH-HHHHS?----??-GG---GE--EE--EE?TT--SS?SS?TTSHH-HHHHH---------S 3S03|A PF00692.14_dUTPase_seed 29 142 !Q:2,5|7,7|12,12|19,19|22,22|26,26|28,29|37,38|43,44|46,46|54,55|59,59|64,64|69,72|75,75|78,79|81,83|90,90|94,95|99,99|102,102|114,118|123,123|125,141 Q:0,1|6,6|8,11|13,18|20,21|23,25|27,27|30,36|39,42|45,45|47,53|56,58|60,63|65,68|73,74|76,77|80,80|84,89|91,93|96,98|100,101|103,113|119,122|124,124 TT????B?SSTT?SEEEEE?SS?EEE?T--TEEEEEE??EEEE??T-TEEEEEE??HHH-HHHH?EEEE--??EE?TT??S-??EEEEEE?SSS-?EEE?TT?EEEEEEEEEEE?---?EEEE?S??-?????????????? 4A6A|A PF00693.13_Herpes_TK_seed 14 308 !Q:0,0|19,19|21,21|23,23|28,30|40,40|42,42|52,71|99,102|107,109|111,119|128,128|147,147|158,162|172,174|187,187|190,193|218,224|233,236|248,252|254,255|257,259|269,269|275,275|279,280|282,282|306,307 Q:1,18|20,20|22,22|24,27|31,39|41,41|43,51|72,98|103,106|110,110|120,127|129,146|148,157|163,171|175,186|188,189|194,217|225,232|237,247|253,253|256,256|260,268|270,274|276,278|281,281|283,305 ?STTSSHHHHHHHHHSGGG?S-S?EEEE???HHHHHTSSS-S?HHHHHHHHH???????????--------?HHHHHHHHHHHHHHHHHHHHHHHTTTS---?EEEE???S?---?----SEEEEEES?THHHHTHHHHHHHHTTSS?HHHHHHHHTT?????TTEEEEEEE??-HHHHHHHHHHHS?SS????HHHHHHHHHHHHHHHHHHHHHHTT??-----TTTTTTTS????HHHHHHHHSTT?????S--S-??GGGSGGGGG?SGGGB?TTS?-B?HHHHHHHHHHHHHHTTEEEEEEE?? 1P72|A PF00694.14_Aconitase_C_seed 18 138 !Q:7,7|9,10|17,18|27,27|49,49|52,52|56,57|60,67|80,81|86,87|95,96|115,115|117,117|129,129 Q:0,6|8,8|11,16|19,26|28,48|50,51|53,55|58,59|68,79|82,85|88,94|97,114|116,116|118,128|130,137 EEEEEEB?S??BHHHHB??GGGGGGTB?HHHHGGGBTTTSEETTTTEES?EE?TTT??EE-------?HHHHHHHHHTTT??EEEE??SSBTBSS??THHHHHHHHTTEEEEEES?B?HHHHHHHHHTT?EEEEESSG 3Q3W|A PF00696.23_AA_kinase_seed 135 459 !Q:0,1|3,4|6,6|10,10|16,16|19,29|34,34|42,47|49,71|76,84|86,86|92,97|99,103|105,108|119,126|132,133|141,144|160,162|165,167|192,196|200,202|213,213|220,220|230,235|238,241|244,244|253,253|255,265|269,270|275,278|289,290|292,293|295,298|306,308|312,315|318,322|326,342|359,362|364,366|377,377|381,381|385,386|389,391|393,393|397,397|405,428|434,435|443,443|446,447|449,450|452,453 Q:2,2|5,5|7,9|11,15|17,18|30,33|35,41|48,48|72,75|85,85|87,91|98,98|104,104|109,118|127,131|134,140|145,159|163,164|168,191|197,199|203,212|214,219|221,229|236,237|242,243|245,252|254,254|266,268|271,274|279,288|291,291|294,294|299,305|309,311|316,317|323,325|343,358|363,363|367,376|378,380|382,384|387,388|392,392|394,396|398,404|429,433|436,442|444,445|448,448|451,451|454,458 ??E--E-EEE?TTTTS-SH-----------HHHH-HHHHHHH------H-----------------------HHHH--------?S?EEEEE??---?T-----T----HHHHHHHHHH--------HHHSS??HHHHHHH----HHHHHHHHHHHHHHH???HH---HHHHHHHHHHHHHHHHHHHHHHHH-----HHT???HHHHHHHHHH-HHHHHH-HHHHHHHHH------TT????EE?HHHHTEEE?S?----------TTS??EEEE---?HHHHHHHHHH--T--T-???EEESSEE---EET----TS----?EEE?---------------?TTHHHHHHHHHHHHTT?---S---EEEEEESSSS?BSS?TTT?-TT?-?B?SEE?HHHHHHH?----------------------?TTSSS??HHHHHHH-HH--H--T??EEEEE 2V4Y|A PF00697.17_PRAI_seed 23 251 !Q:0,0|3,6|19,22|29,30|33,33|37,38|49,52|54,55|63,64|77,77|83,83|85,89|101,101|112,112|114,117|120,125|128,132|138,145|147,147|149,150|153,156|164,192|201,202|212,217|219,220|226,226|233,234|238,238|240,240 Q:1,2|7,18|23,28|31,32|34,36|39,48|53,53|56,62|65,76|78,82|84,84|90,100|102,111|113,113|118,119|126,127|133,137|146,146|148,148|151,152|157,163|193,200|203,211|218,218|221,225|227,232|235,237|239,239|241,250 ?EE????SHHHHHHHHHHT?---SEEEEE??TT?TTB??HHHHHHHHHH??-?E--EEEEESS??HHHHHHHHHHHT?SEEEE?S??--?HHHHHHHHHHS?TTSEEEEEEE?S----SS??????TT?---?EEEEE--------S?S??SS????GGGGTTS??---------------------------TTEEEESS??TTTHHHHHT------T??SEEEE?GGGEEE--TTE-E?HHHHHHHHHH 1NSJ|A PF00698.16_Acyl_transf_1_seed 12 402 !Q:4,5|8,10|21,21|39,39|42,42|49,50|52,52|55,109|132,132|137,141|147,147|162,162|182,182|185,185|193,195|209,213|226,226|242,244|246,248|250,250|253,253|273,279|285,285|289,289|293,298|302,303|314,314|325,327|332,333|338,338|342,342|355,361|365,365|368,368|372,372|374,374|379,379|381,383|399,401 Q:0,3|6,7|11,20|22,38|40,41|43,48|51,51|53,54|110,131|133,136|142,146|148,161|163,181|183,184|186,192|196,208|214,225|227,241|245,245|249,249|251,252|254,272|280,284|286,288|290,292|299,301|304,313|315,324|328,331|334,337|339,341|343,354|362,364|366,367|369,371|373,373|375,378|380,380|384,398 EEEE??TT???TTTTHHHHHS?HHHHHHHHHHHHHTGGG?SS?HHHHHH--T?TT?----------------------------------------------------??TTSHHHHHHHHHHHHHHHHHHH-HHTT--???SEEEE?TTHHHHHHHHTTSS?HHHHHHHHHHHHHHHHTTT-TS?EEEEESS?--HHHHHHTTGGGTT?????EEEETTEEEEEE?HHHHHHHHHHHTTTT-??B???S?SS?TTSGGGTTTHHHHHHHHTT-??????SSEEE?TTT?SEE-----?GGG??HHHHHHHHHS?EEHHHHHHHH---HHTT??EEEE?SSS?SSHHHHHHHHHT-------STT?SS?EEE?S?BTTB?H---HHHHHHHHHHHHTTT??? 2QJ3|A PF00699.15_Urease_beta_seed 165 121 !Q:0,0|3,3|6,11|15,17|20,20|24,28|37,37|41,41|49,49|54,54|57,57|61,70|80,80|82,82|85,85|90,90|92,92|94,94|103,104|107,107|110,110|116,117|120,120 Q:1,2|4,5|12,14|18,19|21,23|29,36|38,40|42,48|50,53|55,56|58,60|71,79|81,81|83,84|86,89|91,91|93,93|95,102|105,106|108,109|111,115|118,119 ?TT?EE-?---?SSE---EE?STT?-?--EEEEEEEE?SSS?EEEETTS?GGGS?TT-EES---------?TTTTTTEEE?S?TT?EEEE?T-T?EEEEEEEE??TT?EE?STTSS??EE? 1FWI|B PF00700.16_Flagellin_C_seed 33 89 !Q:7,9|50,52|87,88 Q:0,6|10,49|53,86 HHHHHHH---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS???SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?? 1UCU|A PF00701.17_DHDPS_seed 13 302 !Q:0,1|8,11|13,13|17,17|19,19|35,37|52,52|72,72|77,79|97,98|104,106|109,111|124,124|127,127|130,130|136,136|142,145|155,155|165,165|167,168|170,172|183,183|191,195|207,208|218,218|233,233|238,238|256,257|275,279|283,286 Q:2,7|12,12|14,16|18,18|20,34|38,51|53,71|73,76|80,96|99,103|107,108|112,123|125,126|128,129|131,135|137,141|146,154|156,164|166,166|169,169|173,182|184,190|196,206|209,217|219,232|234,237|239,255|258,274|280,282|287,301 ??SEEEEE????B?TTS?B?HHHHHHHHHHHHHHT-??EEEESSTTTTGGGS?HHHHHHHHHHHHHHHTTSS?EEEE???SSHHHHHHHHHHTTTSS??EEEEE???SS???HHHHHHHHHHHH-HT?SS?EEEEE?HHHHS????HHHHHHHTT-STTEEEEEE?S??T---HHHHHHHTTS?TTSEEEE?---?HHHHHHHHHTT??EEEESGGGT?HHHHHHHHHHHHTT?HHHH-HHHHHHHHHHHHHTTSS--STTHHHHHHHHHHTSSS?????TTS????HHHHHHHHHHHHHTT 3DI0|A PF00702.21_Hydrolase_seed 239 720 !Q:0,1|8,8|13,14|24,72|76,98|102,102|111,112|119,120|136,155|174,225|229,241|244,244|253,261|268,301|306,306|313,489|505,505|507,512|514,522|530,539|544,551|553,557|563,564|566,570|572,572|585,614|617,618|621,621|623,643|645,645|649,654|661,666|669,684|688,700|706,706|709,709 Q:2,7|9,12|15,23|73,75|99,101|103,110|113,118|121,135|156,173|226,228|242,243|245,252|262,267|302,305|307,312|490,504|506,506|513,513|523,529|540,543|552,552|558,562|565,565|571,571|573,584|615,616|619,620|622,622|644,644|646,648|655,660|667,668|685,687|701,705|707,708|710,719 ??EEEEEI-IIII--EEEEEEEEE-------------------------------------------------EEE-----------------------SSS?HHHHHHHH--HHHHTT??SHHHHHHHHHHHHTT??-----??---------??EEEEEETTTEEEEEETTE----------------------------------------------------EEE-------------EE?HHHHHHHT???--?---TTHHHH----------------------------------HHTT?EEEEEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETTEEEEEEEEEEEE?T------T---------HHHHHHH----------HHHT--------T?----EEEEE?-S-----S?HHHHHHHHHHHT--?---------------------------SE--EE?S?-------------------?G-GGH------HHHHHH------HH----------------TTS--------?----EEEEE?TT-TTHHHHHHSS 2HDO|A PF00703.16_Glyco_hydro_2_seed 136 179 !Q:3,3|5,7|9,16|28,28|30,30|39,51|57,59|66,68|70,71|73,73|76,76|78,81|87,90|94,98|105,107|111,111|121,124|127,127|129,132|134,134|136,137|139,140|143,144|151,153|155,155|159,164|170,171|176,176|178,178 Q:0,2|4,4|8,8|17,27|29,29|31,38|52,56|60,65|69,69|72,72|74,75|77,77|82,86|91,93|99,104|108,110|112,120|125,126|128,128|133,133|135,135|138,138|141,142|145,150|154,154|156,158|165,169|172,175|177,177 EEE-E---E--------EEEEEEESSTT-S?SEEEEEEE-------------EEEES???EEEEEE---E??B?TT?B??--HHHHH????TTS?????EEEEEE-??TTS?SEEEEEESS?--?BB?S----S-S--B?-BE--EEEEEE---E?TTS-----?EEEEE--EEEE?B? 1HN1|A PF00704.23_Glyco_hydro_18_seed 165 681 !Q:0,0|8,11|18,18|20,26|28,28|30,39|44,44|46,51|54,54|71,134|151,152|155,155|157,158|160,160|167,169|171,171|175,175|177,188|199,204|210,210|224,245|249,249|253,253|255,255|260,285|287,288|314,317|319,336|342,351|354,354|358,360|366,369|377,378|385,387|390,395|400,404|406,408|411,411|414,415|418,473|479,479|493,496|508,508|516,516|519,520|524,524|529,557|559,565|569,570|582,607|610,610|618,618|623,623|629,641|645,646|649,651|667,667|674,674|676,676|678,678 Q:1,7|12,17|19,19|27,27|29,29|40,43|45,45|52,53|55,70|135,150|153,154|156,156|159,159|161,166|170,170|172,174|176,176|189,198|205,209|211,223|246,248|250,252|254,254|256,259|286,286|289,313|318,318|337,341|352,353|355,357|361,365|370,376|379,384|388,389|396,399|405,405|409,410|412,413|416,417|474,478|480,492|497,507|509,515|517,518|521,523|525,528|558,558|566,568|571,581|608,609|611,617|619,622|624,628|642,644|647,648|652,666|668,673|675,675|677,677|679,680 ?EEEEEEE----TTGGGS?G-------G-G-------???GGGS?T------TT?SEEEEEEEEEETTEEE---------------------------------------------------------------?SSTTHHHHHHHHHGGG--GT?T--T?EEEEEE---E?TTT?S------------HHHHHHHTSH------HHHHH-HHHHHHHHHHHHT---------------------?SEE-EEE?S?TTST--------------------------T??THHHHHHHHHHHHHHHHHHHHHHHH---?S---------------???EEEEE----------EE?SHH---HHHHH--??HHHHHHH-?SEEEEE???SS?-----TTSS-----B???SS?SS??TT------------------------------------------------------??GGGGG?SHHHHHHHHHHTT-??-GGGEEEEEESE-EEEEEES?TT??STT?BEEE-----------------------------E?---???TTT??TTEEEHHHHTT?-------------------------SS?EEEEETT-TTEE-EEEET-------------TEE--EE???HHHHHHHHHHHHHTT?SEEEEE?G-G-GS 1NWT|A PF00705.13_PCNA_N_seed 13 127 !Q:0,0|7,7|22,22|40,40|64,64|82,82|85,85|92,92|95,95|104,104|109,109|112,113|119,121|124,126 Q:1,6|8,21|23,39|41,63|65,81|83,84|86,91|93,94|96,103|105,108|110,111|114,118|122,123 ?EEEEES?THHHHHHHHHHTTT?SEEEEEEETTEEEEEEE?TTSSEEEEEEEEGGGSSEEEESS?EEEEEEHHHHHHHHHTS?TT?EEEEEE?TT?SEEEEEEE?TTSS?EE--EEEEE???EE??? 3F1W|A PF00706.12_Toxin_4_seed 7 48 !Q:3,3|5,6|10,10|13,13|20,21|26,30 Q:0,2|4,4|7,9|11,12|14,19|22,25|31,47 EEE?S??SSS?SS?SEEEEE--EESS?---?TTEEEEEEEEETTEEEE 2SH1|A PF00707.17_IF3_C_seed 150 100 !Q:0,1|9,9|12,13|31,31|40,41|43,45|47,47|50,51|54,54|68,69|77,83|86,90|96,96|98,99 Q:2,8|10,11|14,30|32,39|42,42|46,46|48,49|52,53|55,67|70,76|84,85|91,95|97,97 ??EEEEEEE?TT??HHHHTHHHHHHHHHHHT-TEEEEEEE??S---S?TT??SS-HHHHHHHHHHHHH--TTTEEES???????SS---??EEEEE-E?? 2CRQ|A PF00708.13_Acylphosphatase_seed 75 129 !Q:0,14|25,25|27,27|29,30|47,48|52,52|56,56|60,63|71,71|76,76|87,89|93,98|106,106|110,123|128,128 Q:15,24|26,26|28,28|31,46|49,51|53,55|57,59|64,70|72,75|77,86|90,92|99,105|107,109|124,127 ?-------------?EEEEEEEEEE-E?S--SSSHHHHHHHHHHHTT-?EEE-EEE?TTS---?EEEEEEE-EHHH-HHHHHHHHTT--?STT-----?EEEEEEE-EEE?????--------?SEEE? 2GV1|A PF00709.16_Adenylsucc_synt_seed 92 680 !Q:10,10|12,12|22,28|31,31|37,37|40,44|48,58|65,67|76,76|81,82|88,88|95,95|100,100|103,103|107,112|121,121|124,125|137,140|143,157|171,175|181,182|184,185|187,191|202,211|216,216|221,221|226,235|237,244|258,301|305,308|311,312|315,316|328,328|330,331|336,336|339,339|343,344|354,354|357,358|369,370|374,377|387,387|395,396|400,411|414,419|426,438|441,486|488,490|492,496|498,498|502,503|505,505|520,520|525,527|533,533|538,541|544,544|556,559|563,582|585,586|588,589|592,592|599,599|608,615|617,618|621,622|624,625|630,630|645,645|647,647|649,663|673,673 Q:0,9|11,11|13,21|29,30|32,36|38,39|45,47|59,64|68,75|77,80|83,87|89,94|96,99|101,102|104,106|113,120|122,123|126,136|141,142|158,170|176,180|183,183|186,186|192,201|212,215|217,220|222,225|236,236|245,257|302,304|309,310|313,314|317,327|329,329|332,335|337,338|340,342|345,353|355,356|359,368|371,373|378,386|388,394|397,399|412,413|420,425|439,440|487,487|491,491|497,497|499,501|504,504|506,519|521,524|528,532|534,537|542,543|545,555|560,562|583,584|587,587|590,591|593,598|600,607|616,616|619,620|623,623|626,629|631,644|646,646|648,648|664,672|674,679 EEEEEESSSS?S?HHHHHHHHH-------HH?SEEEE?SB?????EEE???----?-??EEESSS?--GGGGSTTS-EEEE?-TTBEE?HHHHHH-HHHH-HH-TTT-???--TTEEEETT?EE??HHHHHHHHHHH----HH-????----??????SSHHHHHHHHHTT?-?-?BHHHH--T-?H-----HHHHHHHHHH----------HHHH-HHHH-HHTS---------?S---???-?GGGTHHHHHHHHH--------------------------------------------HHG----GG--EE-?HHHHHHHHHHT-T??EEEE?SS?GGG-?TTTSSTTSS?SS??STHHHHHHHT??GGG??--EEEEEEESE-EEESSSS??TTB--??--------SH------HHHHHH-------------HH----------------------------------------------H---T----?B?TTT??B?EEEEEEHHHHHHHH-HHHT-??EEEEE?GGGG----TT?SEEEEEEEEEE----TTE--------------------EE?-S??SS-HHHHTT?EEEEEEEE??-?----S??TT??S--GGGS?HHHHHHHHHHHHHH-T?E---------------EEEEESSSS-GGGEEE 1LOO|A PF00710.15_Asparaginase_seed 157 661 !Q:3,9|13,13|15,29|31,31|43,50|56,58|61,61|63,63|65,66|71,73|75,75|80,254|257,262|266,267|283,285|289,290|297,298|314,314|317,322|324,324|329,330|333,333|335,344|349,349|366,376|378,378|392,392|404,404|408,408|412,412|414,414|417,417|420,421|424,424|427,428|432,434|439,439|441,475|477,507|510,517|523,524|527,529|531,534|542,542|546,547|560,567|579,579|582,582|584,591|603,609|620,620|622,624|626,626|628,628|631,631|634,635|650,654|659,659 Q:0,2|10,12|14,14|30,30|32,42|51,55|59,60|62,62|64,64|67,70|74,74|76,79|255,256|263,265|268,282|286,288|291,296|299,313|315,316|323,323|325,328|331,332|334,334|345,348|350,365|377,377|379,391|393,403|405,407|409,411|413,413|415,416|418,419|422,423|425,426|429,431|435,438|440,440|476,476|508,509|518,522|525,526|530,530|535,541|543,545|548,559|568,578|580,581|583,583|592,602|610,619|621,621|625,625|627,627|629,630|632,633|636,649|655,658|660,660 EEE-------EEE?S???-----------?E-EEETTTTEEEE-----???HHHHH---HH?G-G--GGGT---S-EEEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EE???-??GGG??HHHHHHHHHHHHHHH---HTT?-SEEEEE??SSSHHHHHHHHHHHE-ES??----S?EEEE??SS?T----------TSTT?SHHHHHHHHHHHHTSS-----------B?SEEEEEESSSSSS?EEEEETTSEEE?BSS?STT-E-EE?SS??SE-EE-?TTS--?EEES?S???--------------------------------B---???--------------------???--EE???????-EEEEE??TT?-?T----HHHHHHH-HTT-?SEEEEEEBTTTB------??GGGHHHHHHHH-HT-T-------?EEEEEESSSBS???---?SSSHHHHHHH-H---T-T?EE?TT??HHHHHHHHHHHHTT?--??HHHH-H 1JAZ|A PF00711.14_Defensin_beta_seed 54 39 !Q:0,1|3,4|16,17|22,22|27,28 Q:2,2|5,15|18,21|23,26|29,38 ??S??TTTTSEEEESS??TTSE-EEEE--ETTTTEEEEE 2NLF|A PF00712.14_DNA_pol3_beta_seed 15 141 !Q:0,0|20,21|24,24|39,40|49,49|60,61|63,71|73,73|91,91|94,94|103,104|111,111|115,121|128,128|130,130|135,140 Q:1,19|22,23|25,38|41,48|50,59|62,62|72,72|74,90|92,93|95,102|105,110|112,114|122,127|129,129|131,134 ?EEEEEHHHHHHHHHHHTTT??SS?SSGGGGEEEEEEET--TEEEEEEE?SSEEEEEEEE??S?-------?B?EEEEEEHHHHHHHHHHS?TT?EEEEEEET--TEEEEE-ETT-------EEEEEE?B?GGGS?--??? 3BEP|A PF00713.12_Hirudin_seed 8 64 !Q:0,5|15,15|21,22|26,26|30,30|34,34|36,36|39,40|43,43|45,63 Q:6,14|16,20|23,25|27,29|31,33|35,35|37,38|41,42|44,44 ??????SSTTBSSSB?STTSB??TTS?EES?STT?S?EE??SS?B??????????????????? 3HTC|I PF00714.12_IFN-gamma_seed 9 139 !Q:0,10|25,25|34,35|44,45|71,72|94,94|106,108|111,111|129,129|131,138 Q:11,24|26,33|36,43|46,70|73,93|95,105|109,110|112,128|130,130 ---------??HHHHHHHHHHHHHT?SSGGGGSS??SSTTGGGG??SHHHHHHHHHHHHHHHHHHHHTTSS?-GGGHHHHHHHHHHHHHHHSTT?HHHHHHHHHHH???TT?TTHHHHHHHSHHHHHTS?S???????? 1EKU|A PF00715.12_IL2_seed 7 162 !Q:0,33|58,61|70,70|72,73|76,79|101,109|111,113|128,137|139,139|142,142|144,144 Q:34,57|62,69|71,71|74,75|80,100|110,110|114,127|138,138|140,141|143,143|145,161 --------------??????--------------HHHHHHHHHHHHHHHHHHHHHHHT????HHHHHTTS?B??BS?-??SGGGGHHHHHTHHHHHHHHHH?????????H---HHHHHHHHHHHHHH??????????B?SS?B?HHHHHHHHHHHHHHHHH 1QVN|A PF00716.12_Peptidase_S21_seed 11 421 !Q:0,4|14,26|33,33|58,59|73,73|79,79|81,82|87,89|100,100|105,129|136,136|141,141|143,143|156,156|159,160|170,173|176,197|199,201|215,215|235,236|238,420 Q:5,13|27,32|34,57|60,72|74,78|80,80|83,86|90,99|101,104|130,135|137,140|142,142|144,155|157,158|161,169|174,175|198,198|202,214|216,234|237,237 ?????HHHHHHHTT?????????????EEEETT?TTBEEEEEEEEEEETTEEEEEEEE??HHHHHHHHHHHTT?HHHHT?S--STTS???HHHHHHHHHT?EEEE????????????????-????????EEEESS?SSTT?B?EEESSHHHHHTT?TT??HHHHHHHHH----TT????--------??????????B???HHHHHHHHHHHHT?TTHHHHHHHHHHHTTGGGS??S???------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 1IEG|A PF00717.18_Peptidase_S24_seed 228 133 !Q:1,3|7,10|12,13|17,18|27,29|36,37|41,51|56,59|62,64|69,70|72,72|75,75|77,86|96,97|99,99|102,102|106,109|113,114|116,123 Q:0,0|4,6|11,11|14,16|19,26|30,35|38,40|52,55|60,61|65,68|71,71|73,74|76,76|87,95|98,98|100,101|103,105|110,112|115,115|124,132 E???STT----T--TTS?-TTEEEEEE---ESEEEE??SSS--------???EEEE????TT?--EEEE--E?SS?T----------TSEEEEEEE--E?TT?EEE----EET--T--------TTEEEEESS 1JHC|A PF00718.15_Polyoma_coat_seed 12 317 !Q:0,3|12,13|17,17|26,28|32,32|34,36|44,44|48,54|60,63|67,67|70,70|77,83|102,103|109,110|113,113|116,116|128,130|133,133|144,144|149,151|153,153|156,162|167,168|176,178|184,187|190,190|195,195|205,206|208,210|213,213|223,224|227,229|237,238|241,243|247,249|251,251|267,268|273,276|280,281|295,295|300,300|311,316 Q:4,11|14,16|18,25|29,31|33,33|37,43|45,47|55,59|64,66|68,69|71,76|84,101|104,108|111,112|114,115|117,127|131,132|134,143|145,148|152,152|154,155|163,166|169,175|179,183|188,189|191,194|196,204|207,207|211,212|214,222|225,226|230,236|239,240|244,246|250,250|252,266|269,272|277,279|282,294|296,299|301,310 ????SSGGGGGS??TTT?EEEEEEEE???BSS?S???STTTSTT?TTB???????SBTTB????TTS?BB?EEEEEE???????TTSSEEEEEEEEEEEEEE??GGGGG??SS-SB?EEETTTTEEEE???BS?EEEEEEEESS?EEEE???S?SS????---SSSS??HHHHHSS???GGGGS--??SS?EEEE?STTTSBTTT??B???SS?SEEEEEEEE??SS???EEEEESS??EE???TTS???B?STTEEEEEEEEEEEE??BSSS????EEE??EEEEEEEEEEEEE?STTS?HHHHGGGSTT?????? 4FMH|A PF00719.14_Pyrophosphatase_seed 157 222 !Q:3,5|9,9|12,13|20,20|24,25|31,43|45,45|49,56|63,63|66,90|95,96|101,102|104,104|106,108|111,111|127,131|143,143|146,146|148,148|152,152|154,156|158,159|165,165|184,189|192,193|195,196|203,203|219,219|221,221 Q:0,2|6,8|10,11|14,19|21,23|26,30|44,44|46,48|57,62|64,65|91,94|97,100|103,103|105,105|109,110|112,126|132,142|144,145|147,147|149,151|153,153|157,157|160,164|166,183|190,191|194,194|197,202|204,218|220,220 EEE---EEE?TT??SEEEEE?TTT??EEEEE-------------E?SSS-----???SSEEEE?TT???----------------------TTSS??EEEE??S-S???TT?EEEEEEEEEEEEEES-----SSEEEEEEEEE?TT-T?STT-T---T??SGGGS?HHHHHHHHHHHHHTTTTS------TT??E--EEEEEE?HHHHHHHHHHHHHHH-H? 1MJX|A PF00720.12_SSI_seed 22 99 !Q:0,3|19,21|28,28|32,32|36,36|49,50|54,54|57,64|71,71|73,75 Q:4,18|22,27|29,31|33,35|37,48|51,53|55,56|65,70|72,72|76,98 ????EEEEEEEESSSTTSS???EEEEEE?SSS?EEE?TTHHHHHHHHHH--HTT?TT??---???SSEEEE?B???EEEEEEEEETTEEEEEEEEESSH 4HX3|B PF00721.16_TMV_coat_seed 47 192 !Q:0,6|9,11|21,23|38,38|56,66|68,68|72,74|77,92|95,95|110,115|125,131|138,142|150,151|155,155|171,171|173,177|179,181|183,187 Q:7,8|12,20|24,37|39,55|67,67|69,71|75,76|93,94|96,109|116,124|132,137|143,149|152,154|156,170|172,172|178,178|182,182|188,191 ????--?SG---GGHHHHSTT???HHHHHHHHHHHSSS?SSSHHHHHHHHTTTTTS-?------???S?SSS???SS-?------?----???TT?TTSHHHHHHHHTTS?--???TTTTTGGGT----???HHHHHH-----HHHHHHH--HHH-HHHHHHHHTHHHHHT-T----?S???H-----HHHT 3J06|A PF00722.16_Glyco_hydro_16_seed 120 285 !Q:7,7|10,10|18,23|26,31|40,40|42,63|65,67|73,75|78,78|83,85|93,95|97,98|108,109|111,116|118,120|123,124|129,129|133,135|140,144|152,155|160,173|177,181|184,184|187,187|190,190|198,198|216,217|221,221|223,233|235,235|238,238|241,241|246,247|251,251|253,259|267,276|279,281 Q:0,6|8,9|11,17|24,25|32,39|41,41|64,64|68,72|76,77|79,82|86,92|96,96|99,107|110,110|117,117|121,122|125,128|130,132|136,139|145,151|156,159|174,176|182,183|185,186|188,189|191,197|199,215|218,220|222,222|234,234|236,237|239,240|242,245|248,250|252,252|260,266|277,278|282,284 HHHHEEE-EE?GGGEEEE------GG------GTEEEEEE?S----------------------S?-?EEEEE---SS?EEEE---EEEEEEE???S??TTEEEEEEE--E---?-?S---SS??EEEE-EEE??-STTS?---?EEEEEEE----BTTB??------?----?EEE??---SS?TT-TS?EEEEEEE?SSEEEEEETTEEEEEEE??GGG-T?----?-?---S?SS?BE-EEEE--EEE?T-------TTTTGGG----------TS???GGG 1GBG|A PF00723.16_Glyco_hydro_15_seed 26 1050 !Q:14,14|17,17|20,21|24,24|26,26|28,28|30,30|35,44|46,47|63,77|84,85|95,95|106,107|112,112|118,119|123,124|133,134|136,139|141,143|160,161|168,175|187,189|204,206|209,209|213,218|225,226|247,300|303,304|317,323|325,328|331,356|358,360|365,366|370,388|391,394|398,411|419,420|423,424|426,426|431,431|435,443|457,457|462,462|468,469|473,480|483,484|487,488|491,562|565,565|568,616|623,915|933,933|937,937|951,967|974,976|1004,1004|1007,1010|1014,1014|1016,1025|1028,1030|1037,1037 Q:0,13|15,16|18,19|22,23|25,25|27,27|29,29|31,34|45,45|48,62|78,83|86,94|96,105|108,111|113,117|120,122|125,132|135,135|140,140|144,159|162,167|176,186|190,203|207,208|210,212|219,224|227,246|301,302|305,316|324,324|329,330|357,357|361,364|367,369|389,390|395,397|412,418|421,422|425,425|427,430|432,434|444,456|458,461|463,467|470,472|481,482|485,486|489,490|563,564|566,567|617,622|916,932|934,936|938,950|968,973|977,1003|1005,1006|1011,1013|1015,1015|1026,1027|1031,1036|1038,1049 HHHHHHHHHTBTTT?TT?TT??TT?B?S?S?BSSS----------B??SEEHHHHHHHHHHHH---------------HHHHTT-?GGGHHHHHH-HHHHHHHHTT??BTTB?TTTSG--GGG??EEETTTEE??S?--?S???THHHHHHHHHHHHHHH--HHHHTT?-------HHHHHHTHHHH---HHHHHHHHHHHTTS?--EE?TTS----??EEEEHH--HHHHHHHHHHHHHHHHHHTT--?-------------------------------------------------??HH--HHHHHHHHHHHH-------G----GG--------------------------B?--SSSB??EET------------------?SS????HHH--------------HHHHHHT??TT??S?GGGT?TTS---------HHHHHHHHHHHHT-TTTT?GGGTT??TTS?----???BS-?TT??GG------------------------------------------------------------------------GS?BB-------------------------------------------------HHHHHH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHHHHHHHHHHHHHHTE-EEE?TTTHHHHHHHSTT---------------??SEEEET---TSHHHHHHHHHHHHHHHHHHHHHHHHS?TT????SEE?T----------TT??-EESSSS?HHHHHHHHHHHH 1AYX|A PF00724.15_Oxidored_FMN_seed 12 384 !Q:4,4|10,10|20,28|35,36|49,49|53,53|67,70|74,74|97,97|105,106|111,112|121,127|132,132|135,136|138,138|150,151|153,155|158,159|169,169|181,181|184,184|191,192|199,199|203,203|207,210|215,215|237,237|241,245|251,251|254,255|259,261|287,289|293,293|297,297|300,300|302,302|306,306|311,313|315,316|318,320|327,328|330,330|337,339|342,342|344,345|349,349|362,363|369,369|380,382 Q:0,3|5,9|11,19|29,34|37,48|50,52|54,66|71,73|75,96|98,104|107,110|113,120|128,131|133,134|137,137|139,149|152,152|156,157|160,168|170,180|182,183|185,190|193,198|200,202|204,206|211,214|216,236|238,240|246,250|252,253|256,258|262,286|290,292|294,296|298,299|301,301|303,305|307,310|314,314|317,317|321,326|329,329|331,336|340,341|343,343|346,348|350,361|364,368|370,379|383,383 GGGS?EEETT-EEESSSEEB???-?????BTTTTB??TTTHHHHHHHHT?STT?EEEEEEEESSGGG?-??TTS?BSSSHHHHHHHHHHHHHHHHTT?EEEEEEE??GGGS?-HHHHHHTT?-----?EEES?SS??S?HHHHHHHHHTT??E---EE??HHHHHHHHH-HHHHHHHHHHH-TT?SEEEEE??TTSHHH-HHH?TTT????STTS-SSHHHHTHHHHHHHHHHHHHH?GGG-----EEEEE?TT??TTT?-?GGGSTTHHHHHHHHHHHHHHHHHTT???SEE-EEE?TT?S?TTS?TTSS???S??T---THHHHH??S?EEEESS--?TT?H--HHH-HHHTTSTTEEEE??HHHHH?TTHHHHHHHT???B 1O94|A PF00725.17_3HCDH_seed 77 108 !Q:24,24|37,38|40,40|42,42|51,51|61,67|76,78|82,84|95,96|107,107 Q:0,23|25,36|39,39|41,41|43,50|52,60|68,75|79,81|85,94|97,106 TTTHHHHHHHHHHHHHHHHHTTSS?HHHHHHHHHHHH??S-S?HHHHHHHH?HHHHHHHHH-------HHHHTTTT?--GGG???HHHHHHHHTT??BTTTTBSSSB? 3ZW8|A PF00726.12_IL10_seed 3 170 !Q:0,25|54,57|59,59|62,62|97,97|129,131 Q:26,53|58,58|60,61|63,96|98,128|132,169 --------------????????????SSTTTTHHHHHHHHHHHHHTTHHHHHHH????S?SS?HHHHHHHHSTTHHHHHHHHHHHHHHHTHHHHHTT?TTTHHHHHHHHHHHHHHHHHHHHSTTSSGGG???HHHHHHHHHHHHTTHHHHHHHHHTHHHHHHHHHHHHHH 1LK3|A PF00727.13_IL4_seed 8 128 !Q:0,3|20,22|31,31|36,37|39,40|62,62|67,67|69,69|96,96|98,105|109,110 Q:4,19|23,30|32,35|38,38|41,61|63,66|68,68|70,95|97,97|106,108|111,127 ????HHHHHHHHHHHHHTTS-??SGGGSEEE?TTTT??S??HHHHHHHHHHHHHHHHHHHTT?HHHH?S?HHHHHHHHHHHHHHHHHHHHHHHHHT?S????????EEE--HHHHHHHHHHHHHHHHH 3BPN|A PF00728.17_Glyco_hydro_20_seed 56 600 !Q:0,0|9,9|12,12|14,16|32,33|39,39|41,41|43,49|51,51|53,53|55,61|64,64|75,75|77,77|80,80|85,124|128,128|131,131|134,135|137,137|153,153|165,165|184,184|192,195|198,204|208,209|214,215|218,218|240,240|242,244|246,246|251,251|254,254|256,256|269,270|277,277|281,283|288,288|291,293|303,305|308,321|329,336|350,354|368,385|387,397|410,412|415,421|433,445|449,449|454,455|458,460|467,467|471,471|475,475|477,478|481,481|483,485|492,493|499,517|523,525|529,536|540,541|543,556|564,565|568,575|597,599 Q:1,8|10,11|13,13|17,31|34,38|40,40|42,42|50,50|52,52|54,54|62,63|65,74|76,76|78,79|81,84|125,127|129,130|132,133|136,136|138,152|154,164|166,183|185,191|196,197|205,207|210,213|216,217|219,239|241,241|245,245|247,250|252,253|255,255|257,268|271,276|278,280|284,287|289,290|294,302|306,307|322,328|337,349|355,367|386,386|398,409|413,414|422,432|446,448|450,453|456,457|461,466|468,470|472,474|476,476|479,480|482,482|486,491|494,498|518,522|526,528|537,539|542,542|557,563|566,567|576,596 ?SEEEEEEE?SS-S???HHHHHHHHHHHHHTT??EEEEE?B?S-------S?B?B??-----TT?THHHHTTTEE?S?TT?SSSB??-------------------------------------?TTS?SS?EE??B?HHHHHHHHHHHHHTT?EEEEEEEESSS?HHHHHHHHHHHHHHHHTT?HHHHHTT????TT???????TTS??GGGS??TT?HHHHHHHHHHHHHHHHHHHHH-T???S?EEEE?TT?S?GGGSTTEEETTS??TTSEEE?GGG???TTTT?HH---HHHHHHTTS--?SS--------------GGGHHHH--------HHHHHHHHHHHTT??---EEEEEGGGGTTSS----------------?-G-----------GGSSSSEEEEEE???TT-------TTHHHHHHHHH-------------HTT?EEEE??HH---HHBTTS?SSS?TTS?S??SS?S???HHHHHH??TTSGG-------------------GGGGT???TTS-----???EEE??S????---------?SEEEEEE??TT??------SHHHHHHHHTTHHHHHHHHHH??? 3NSM|A PF00729.13_Viral_coat_seed 13 242 !Q:0,35|48,50|53,55|61,63|66,66|71,71|74,74|78,78|103,103|105,105|108,110|119,119|123,126|133,134|141,141|145,161|167,176|178,179|182,184|186,187|195,196|198,207|215,218|222,223|235,236|238,238|240,241 Q:36,47|51,52|56,60|64,65|67,70|72,73|75,77|79,102|104,104|106,107|111,118|120,122|127,132|135,140|142,144|162,166|177,177|180,181|185,185|188,194|197,197|208,214|219,221|224,234|237,237|239,239 ???????--???????-?????????-????----?EEEEEEEEEEEE???SS--?EEGGG???TT-TEES?TT?TTT?TTTHHHHTTBSEEEEEEEEEEEEE?S?TT???EEEEEEES?TTS????SHHHHT??SEEEEE?TTS----------------?EEEEE???-------S??EE???S??SSGGGTS??E----------EEEEEES--??SSS??EEEEEEEEEEE??B?S?? 2VQ0|A PF00730.20_HhH-GPD_seed 72 204 !Q:9,9|24,41|50,51|62,76|102,103|105,105|112,139|143,144|157,169|183,183|186,189|202,202 Q:0,8|10,23|42,49|52,61|77,101|104,104|106,111|140,142|145,156|170,182|184,185|190,201|203,203 HHHHHHTTS?HHHHHHHHHHHHHH?----------------?SHHHHHSS?-HHHHHHHTGG---------------GSSHHHHHHHHHHHHHHHHHHSTTS??S?HHHHTT----------------------------STT??HHHHHHHHHHHH??---????--??HHHHHHHHHHTSS?TT--??HHHHHHHHHHHS?G 4DK9|A PF00731.15_AIRC_seed 224 191 !Q:0,0|8,8|16,22|32,32|35,49|56,57|61,61|75,75|78,79|88,88|90,91|100,101|104,104|111,120|122,122|136,137|140,142|145,146|149,151|167,171|174,174 Q:1,7|9,15|23,31|33,34|50,55|58,60|62,74|76,77|80,87|89,89|92,99|102,103|105,110|121,121|123,135|138,139|143,144|147,148|152,166|172,173|175,190 ?EEEEEES?GGGHHHH-------HHHHHHHHH-TT--------------?EEEEEE??TTT?HHHHHHHHHHTTT-TT??EEEEEEES-S??HHHHHHHH?-SS?EEEEEE?--------?T-TTTTHHHHHHHHT??TT???EE??TT--?HHHHHHHHHHHHHTT----?HH-HHHHHHHHHHHHHHHH 4JA0|A PF00732.14_GMC_oxred_N_seed 20 343 !Q:6,7|24,25|33,35|39,43|62,63|66,69|74,76|79,80|82,82|92,93|95,99|111,112|115,115|131,134|142,145|150,150|159,162|165,165|167,167|171,172|184,188|190,192|197,201|205,207|211,211|214,214|217,218|229,229|231,231|240,240|248,257|259,261|266,266|280,285|298,298|300,300|315,315|324,326|329,332|335,336|339,340 Q:0,5|8,23|26,32|36,38|44,61|64,65|70,73|77,78|81,81|83,91|94,94|100,110|113,114|116,130|135,141|146,149|151,158|163,164|166,166|168,170|173,183|189,189|193,196|202,204|208,210|212,213|215,216|219,228|230,230|232,239|241,247|258,258|262,265|267,279|286,297|299,299|301,314|316,323|327,328|333,334|337,338|341,342 EEEEEE??SHHHHHHHHHHTTSTT??EEEEESS???TTS?----HHHHBGGGTTTTTTSTTB??EE????TTTS???EE??B?STTGGGGTS??B?????HHHHHHHHHTT??TT?SHHHHHHHHHHHEEE????HHHHHHT????GGGS?SSSSEEEB????SS?B?THH--HHHHHHHHTTT??---B???TTSS--???EEE???BSB?TT?BB??HHHHHTGGGT-T?TTEEEEES?EEEEEEE----------E--?SSSS?EEEEEEEEEETTE------EEEEEEEEEEEE?S?TTTHHHHHHHTTBS?HHHHGGGT???SB???-TT??BB??EE 1NAA|A PF00733.16_Asn_synthase_seed 104 518 !Q:14,27|30,30|35,36|51,63|65,97|107,107|109,157|171,171|173,174|180,181|184,185|191,192|201,204|207,209|226,243|247,248|252,253|261,262|264,264|266,269|275,276|298,404|416,416|420,420|424,424|434,434|436,436|441,478|488,495|500,500|506,517 Q:0,13|28,29|31,34|37,50|64,64|98,106|108,108|158,170|172,172|175,179|182,183|186,190|193,200|205,206|210,225|244,246|249,251|254,260|263,263|265,265|270,274|277,297|405,415|417,419|421,423|425,433|435,435|437,440|479,487|496,499|501,505 HHHHHHHHHHHHHT?------------?SS?EEEE??SSHHHHHHHHHHHH-------------H?????-?????--------------????????EEEEEESTT?H-------------------------------------------------HHHHHHHHHHHHT?E--EEEEE??HH--HHHHH--HHHHHHHH????HH---HHHHHHHHHHHHHHHH------------------HTT??EEE??TTHHHHH--T?S----GGGGG??SHHHHHHHHHHHHHHGGGTHH-----------------------------------------------------------------------------------------------------------HHHHHHHHTTT?EEE?GGG?HHHHHHHHH-S?GGGT?-?????------------------------------?TTHHHHHHH--------GGGS?HHHHT---------??? 1MB9|A PF00734.13_CBM_1_seed 133 39 !Q:2,3|7,9|12,16|18,24|27,28|30,31 Q:0,1|4,6|10,11|17,17|25,26|29,29|32,38 TT?-EEE?--TT--?-?S???--??TT??E--EEEETTE 1AZ6|A PF00735.13_Septin_seed 14 320 !Q:1,1|11,11|27,66|71,71|77,81|91,107|128,139|146,146|148,153|164,168|180,180|198,231|238,238|242,245|249,258|263,263|272,277|287,287|289,291|310,319 Q:0,0|2,10|12,26|67,70|72,76|82,90|108,127|140,145|147,147|154,163|169,179|181,197|232,237|239,241|246,248|259,262|264,271|278,286|288,288|292,309 H?EEEEEEEES?TTSSHHHHHHHHHTS?????---------------------????????-?????EEEE-EEEEE????-EEEEEEEEE???????????-?????HHHHHHHHHHHHHHHHHTSS??-?????????EEEEEE?S??????HHHHHHHHHH?????EEEEESSGGGS?HHHHHHHHHHHHHHHHH???????-????????----------????????HHHHHH?SEE????SSB???--?????BEEE?SSBEEETT??????HHHHHHHHH-H???HHHHHHHTHHHHHHHHHH?????????? 3T5D|A PF00736.14_EF1_GNE_seed 87 125 !Q:0,0|3,6|16,17|21,21|30,30|33,35|38,38|42,42|53,53|63,63|65,65|69,69|74,74|79,80|83,83|87,112|120,121|123,124 Q:1,2|7,15|18,20|22,29|31,32|36,37|39,41|43,52|54,62|64,64|66,68|70,73|75,78|81,82|84,86|113,119|122,122 ?EE----EEEEEEESS--TTS?HHHHHHHH-HH???TT?EEE-EEEEEESSSS?EEEEEEEEE?T-TSS?HHHH-HHHH--TT?TTT--------------------------EEEEEES??B?? 1IJE|B PF00737.15_PsbH_seed 19 55 !Q:0,1|11,11|14,14|17,18|21,22|53,53 Q:2,10|12,13|15,16|19,20|23,52|54,54 ??HHHHHHTTT-TT?TT??BS--TTTTHHHHHHHHHHHHHHHHHHHHHHTTSS?B 3PRR|H PF00738.13_Polyhedrin_seed 17 235 !Q:0,2|21,39|47,48|69,69|76,80|97,97|99,100|121,124|132,134|137,140|145,146|148,148|151,152|155,155|161,161|163,178|194,196|204,204|207,207|224,225|227,231|234,234 Q:3,20|40,46|49,68|70,75|81,96|98,98|101,120|125,131|135,136|141,144|147,147|149,150|153,154|156,160|162,162|179,193|197,203|205,206|208,223|226,226|232,233 ???EEEETTEEEEEHHHHHHT???????????????????GGGSEEE??TTTSSSEEEEEEEEEEEEEE?TTEEEE?????HHHHHHHHHHHHHHHH?S??SEEEEEEEEEEEEEEESSSS????EEEEEES???SS????SEEE??S?EE??TT?EEEEE?B????????????????SSHHHHHHTTGGGGB???EEEEEES?SS?EEEEEEEEEEEEEEEE??S?????SS? 2WUX|A PF00740.13_Parvo_coat_seed 24 649 !Q:0,15|19,26|51,52|54,54|56,57|59,59|65,68|73,73|76,78|81,81|85,87|98,101|107,108|142,143|145,150|156,156|159,160|166,166|169,170|172,175|181,181|183,184|186,186|190,190|192,193|201,215|219,223|227,227|230,235|239,242|246,250|256,257|261,261|264,265|268,270|273,278|281,282|284,287|293,304|307,308|313,322|326,331|334,334|337,337|339,341|345,351|353,354|360,363|366,366|377,403|408,408|414,414|420,420|426,426|429,430|432,435|437,438|444,445|447,448|451,453|457,458|461,461|464,465|468,469|471,485|488,489|492,492|495,496|503,504|506,516|520,524|529,535|540,541|544,547|551,552|554,556|559,559|563,563|566,570|576,578|580,580|582,587|590,590|592,595|597,598|615,615|617,621|624,630|632,634|637,637|646,647 Q:16,18|27,50|53,53|55,55|58,58|60,64|69,72|74,75|79,80|82,84|88,97|102,106|109,141|144,144|151,155|157,158|161,165|167,168|171,171|176,180|182,182|185,185|187,189|191,191|194,200|216,218|224,226|228,229|236,238|243,245|251,255|258,260|262,263|266,267|271,272|279,280|283,283|288,292|305,306|309,312|323,325|332,333|335,336|338,338|342,344|352,352|355,359|364,365|367,376|404,407|409,413|415,419|421,425|427,428|431,431|436,436|439,443|446,446|449,450|454,456|459,460|462,463|466,467|470,470|486,487|490,491|493,494|497,502|505,505|517,519|525,528|536,539|542,543|548,550|553,553|557,558|560,562|564,565|571,575|579,579|581,581|588,589|591,591|596,596|599,614|616,616|622,623|631,631|635,636|638,645|648,648 ?-------????????TTS????????EEEEEEETTEEEEEEEEEEEEEEE??S?S--S?EEEEE????SSTT?TT---ST?GGG???EEEEEEEEEE????SHHHH??HHHHHHHHHHEEEEEEEEEEEEEEEEEEEEEEE??S??????EEEEE?SS??EEEEE?TT??S????GGGGT?S??S?TTS?B??EEEEEEE??------------?EEE-????TTS?TT-?-???EEE????GGG?????HHHHS??EEE?TT??EE???EE??-???EE??B????GGGSS???-------??SS??SSTT??????---?TTT????--BS?TT?S???TTT-------B??SSEES????SS?EEEETTEEEE?????-------------------???TTTT?TGGGT?EEEEE?GGGTS?TT??S----S??EEEEE??S??SS???GGG??EE?SS??SS??G---------------GG--EE?TT??BTTBTT??G-----------GGS?????TTEE???????BTTS??EE????SSS??S??-SS?SEE?SS?????EEEEE???B?S---???TT-S????B??EEEEEEEEEEEEEEEE-E?????SS???????B??-TT?TTBGGGGS??T 1MVM|A PF00742.14_Homoserine_dh_seed 147 252 !Q:0,0|9,9|14,14|22,23|35,38|41,44|59,59|61,61|63,63|86,92|96,96|99,100|104,105|108,130|136,136|147,164|168,169|172,183|188,188|206,208|222,227|236,236 Q:1,8|10,13|15,21|24,34|39,40|45,58|60,60|62,62|64,85|93,95|97,98|101,103|106,107|131,135|137,146|165,167|170,171|184,187|189,205|209,221|228,235|237,251 ?HHHHHHTT-TTTS?EEEEEEE??HHHHHHHHHHH----HH-???HHHHHHHHHHHTSS?S-S?HHHHTSHHHHHHHHHHHHHHHT???--?-GGG?EE??STT??HH-----------------------HHHHH-HHTTEEEEEE------------------EEE--EE-----------?SSSE-EEEEEEEEEETTSTGGG-??TTEEEEEEEETTT------EEEEEEEE?SSHHHHHHHHHHHHH 3ING|A PF00743.14_FMO-like_seed 5 533 !Q:0,1|7,8|24,26|30,30|36,36|41,42|48,53|56,56|58,58|61,61|66,66|71,71|77,77|80,80|104,104|123,123|130,132|144,146|152,158|164,165|174,176|189,190|214,220|224,271|275,283|288,293|298,304|308,308|315,315|318,318|320,320|326,328|331,333|337,337|341,345|349,349|355,356|361,361|367,367|369,370|372,373|376,376|396,399|417,418|441,448|461,479|485,485|492,494|496,496|500,507|509,512|515,515|519,523|530,532 Q:2,6|9,23|27,29|31,35|37,40|43,47|54,55|57,57|59,60|62,65|67,70|72,76|78,79|81,103|105,122|124,129|133,143|147,151|159,163|166,173|177,188|191,213|221,223|272,274|284,287|294,297|305,307|309,314|316,317|319,319|321,325|329,330|334,336|338,340|346,348|350,354|357,360|362,366|368,368|371,371|374,375|377,395|400,416|419,440|449,460|480,484|486,491|495,495|497,499|508,508|513,514|516,518|524,529 ??EEEEE??SHHHHHHHHHHHHTT???EEE?SSSSS?GGGS??TTSSB??????TT?B?SS?GGGT?BTTB?HHHHH?SS?BHHHHHHHHHHHHHHHTGGGGEE?SEEEEEEEEETTEEEEEE-ETTTTE---EEEEEESEEEE???SSSEE????--?BTTTT??SEEEEGGG???GGGGBTSEEEEE??SHHHHHHHHHHHHTTBSEEEEEE-------SSS??????-----------------------------------------?TTE---------EEEE?-----EEEE?------SSE-EEETTS?EE-E?SEEEE???EE???TTB?TTT?????SSS?EETTT--EETT?TTEEE?S?-S??SS?HHHHHHHHHHHHHHHTTSS????HHHHHHHHHHHHHHHHT??SHHHHHHHHHHHHHHHHHTSSS----????HHHHHHHHHHHH-------------------HHHHH?TTTGGG???B?TTT------??B????SS?GGG?????HHHHHS??? 4A9W|A PF00745.15_GlutR_dimer_seed 164 132 !Q:8,10|24,24|26,29|55,58|60,74|96,96|98,99|104,105|109,113|123,124|126,130 Q:0,7|11,23|25,25|30,54|59,59|75,95|97,97|100,103|106,108|114,122|125,125|131,131 HHHHHHHH---HHHHHHHHHHHHH-H----HHHHHHHHHHHHHHHHHHHHHHHHS?---S?----??-??-????TTHHHHHHHHHHHHHHHHHHS-S?-TTTT--THH-----HHHHHHHHH--H-----T 1GPJ|A PF00747.12_Viral_DNA_bp_seed 11 1251 !Q:0,13|15,17|20,20|29,30|43,43|47,47|49,49|54,55|61,61|64,66|77,83|94,94|102,102|107,108|111,115|129,135|142,144|154,155|177,177|181,181|185,185|210,211|213,214|219,219|222,222|226,226|229,233|235,237|258,258|260,260|274,274|277,278|280,281|283,283|286,287|290,320|346,347|349,349|351,353|358,358|391,391|404,418|420,421|430,430|437,437|440,440|444,444|446,446|452,456|459,459|461,465|476,476|490,493|495,502|514,515|517,517|520,521|528,528|540,546|548,550|557,559|561,562|564,564|568,568|570,635|653,654|657,662|665,666|670,670|674,674|704,709|717,717|725,726|731,731|764,764|767,767|772,775|803,811|813,814|818,818|820,820|823,824|828,830|834,835|850,875|877,878|881,883|904,906|909,909|912,913|925,925|927,929|932,932|934,934|941,941|956,959|961,963|983,984|987,989|1001,1001|1004,1004|1012,1012|1014,1018|1036,1036|1039,1040|1049,1049|1057,1058|1069,1079|1086,1087|1091,1093|1097,1097|1099,1108|1110,1113|1123,1124|1130,1143|1154,1155|1157,1158|1160,1160|1179,1180|1182,1183|1193,1194|1216,1219|1228,1250 Q:14,14|18,19|21,28|31,42|44,46|48,48|50,53|56,60|62,63|67,76|84,93|95,101|103,106|109,110|116,128|136,141|145,153|156,176|178,180|182,184|186,209|212,212|215,218|220,221|223,225|227,228|234,234|238,257|259,259|261,273|275,276|279,279|282,282|284,285|288,289|321,345|348,348|350,350|354,357|359,390|392,403|419,419|422,429|431,436|438,439|441,443|445,445|447,451|457,458|460,460|466,475|477,489|494,494|503,513|516,516|518,519|522,527|529,539|547,547|551,556|560,560|563,563|565,567|569,569|636,652|655,656|663,664|667,669|671,673|675,703|710,716|718,724|727,730|732,763|765,766|768,771|776,802|812,812|815,817|819,819|821,822|825,827|831,833|836,849|876,876|879,880|884,903|907,908|910,911|914,924|926,926|930,931|933,933|935,940|942,955|960,960|964,982|985,986|990,1000|1002,1003|1005,1011|1013,1013|1019,1035|1037,1038|1041,1048|1050,1056|1059,1068|1080,1085|1088,1090|1094,1096|1098,1098|1109,1109|1114,1122|1125,1129|1144,1153|1156,1156|1159,1159|1161,1178|1181,1181|1184,1192|1195,1215|1220,1227 ?????----?????B???EE?SEEEEEEE??SSTHHHHHHHSB?BTT?S?EEEE??BTTTB?TT???EEEEEEEEEE???????EEEEEEEEEB?SEEEEEE?GGGS??SB???-?HHHHHHHHHHHHT???????GGGGGG???HHHHHHHHT??TTSEEEEEEEBTTTHHHHHTT?EEE?GGG?EEEEETTEEEEEEEEEEGGGGSTT??S??SSTT?TT?TTS?TT?????B???HHHHHHHHHHTHHHHHHHTT?S?HHHHHHHHHHHHH?TT??S??S?TT??EE?????????-------??????????-????SHHHHHHHHHHHHHHHHHHHHHHTS??S-S???BGGG?GGGSSTTSSSTTHHHHHHHHHHHHHHHHHHHH?TTBTTTEEEEEE??????????-----S??TTSEEEEE?TTTTTS?EE?TTS?B?STTTT?????SS?S?????HHHHHHHTTT?HHHHHHHHHHHTT????S????????HHHHHHTTTTS??S?SS??TTTTTT?HHHHHHHTGGG???????S???EEEEEE???S??B?STT?S????????????-?????????------------------------------------------??HHHHHHHHHHHHHHTTS??TT-----?TT??TTH-HHH?SSHHHHHHHHHHHHHHHHHHHHHHHHHHH??????HHHHHTT?EEEEEEE??TTSS?SSHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS?TT?TTHH----HHHHHHHHHHHHTTTTSSSEEEEEEEB?????????B??TTT?S-SS??BTT???EES??EEEEEEEEEEEEES???????--?????????????????B??SS???GGGSTTHHHHHHTHHHHSTT???TT?SS??HHHHHHHHHHT?S?--SS?S?TTHHHH-HHHHHHHHHHHHHH????S???SHHHHHHHHHHHHHHHHTT??SB???EEEEEEEEEES?SS-SGGGGGG?S?---?STTHHHHHHHHHHTGGG?TT??EEEEEEES?HHHHHHT??EEEEEEEEEE???????????EEEEEE??SSG---GGT?T----------T????TTEEEEEEE??BTTTB??-???????????HHHHHHHHTT--S??S?HHHHHHHHHHTTSSGGGG--G??HHHHHHHSS?-HHHHHHHHHHHHHHHHHTTSS????HHHHHHTT????????--------------? 1URJ|A PF00748.14_Calpain_inhib_seed 24 152 !Q:0,75|87,103|106,111|114,117|120,120|126,126|135,151 Q:76,86|104,105|112,113|118,119|121,125|127,134 ------------------------------------?-------------------------------------?-HHHHHHHHHTT????????--???????SS????-?EE????BT?SGGGS?HHHHHHHT????-???????????? 3DF0|C PF00749.16_tRNA-synt_1c_seed 18 343 !Q:1,1|6,8|12,13|33,33|40,43|47,48|64,66|68,74|77,79|106,108|117,118|122,131|136,137|146,146|153,153|155,155|159,159|164,166|169,169|177,177|183,195|203,203|208,208|222,222|246,247|249,252|258,261|266,268|286,286|290,290|300,301|303,307|318,320|323,326|328,328 Q:0,0|2,5|9,11|14,32|34,39|44,46|49,63|67,67|75,76|80,105|109,116|119,121|132,135|138,145|147,152|154,154|156,158|160,163|167,168|170,176|178,182|196,202|204,207|209,221|223,245|248,248|253,257|262,265|269,285|287,289|291,299|302,302|308,317|321,322|327,327|329,342 S?EEEE???SSS??BHHHHHHHHHHHHHHHHTT?EEEEEE????GGG??HHHHHHHHHHHHHTT???S-------SS--?EEGGGGHHHHHHHHHHHHHTTSEEEE???HHHHHHHH??SSS-----?????TTTT??HHHHHHHH-HHHHTT?S?TTS?EEEE???TT?SSGGGSS?EEEEE????---------BTTTBTS?SEEE?HHHHHHHHHHHHT?SEEEEEGGGTTTHHHHHHHHHSS??S?-??EEEEE????BTTS???HHHHHHHHHTTSSSSTT?TTS?BHHHHHHHT??H-----HHHHHHHHHH???SS?-??B?HHHHHHHHHHHHHH 2HZ7|A PF00750.14_tRNA-synt_1d_seed 9 375 !Q:13,15|17,17|20,20|26,29|34,36|58,58|64,65|68,69|84,85|92,92|111,111|116,116|135,136|158,158|164,166|169,176|182,182|198,198|200,201|214,218|222,222|234,234|251,252|259,260|278,282|292,295|297,303|306,308|314,316|330,330|336,336|340,342|344,344|365,365|369,369|372,373 Q:0,12|16,16|18,19|21,25|30,33|37,57|59,63|66,67|70,83|86,91|93,110|112,115|117,134|137,157|159,163|167,168|177,181|183,197|199,199|202,213|219,221|223,233|235,250|253,258|261,277|283,291|296,296|304,305|309,313|317,329|331,335|337,339|343,343|345,364|366,368|370,371|374,374 HHHHHHHHGGGTT???S?SS?EEEEE????BTTS???HHHHHHHHHHHHHHHHHHHTT?EEEEE??BB??SHHHHHHHHHHHHH??HHHHHH?HHHHHHHHHHHHHHHHHH?SSSS?TTTSHHHHHHHHHTTSSS??TTTTTTHHHHHHHHHHHHHHH-HHHTT???SB??------BSTTS?HHHHHHHHHHHHHHT?B??BTTBEEEEGGGT----?TTS?EEEEEETTTEE?HHHHHHHHHHHHHHHH??SEEEEE??GGGHHHHHHHHHHHHHT?-?--GGGGGEEEE????E-------ES???STTSS???HHHHHHHHHHHHH-HHHHH?TTT???S?HHHHHHHHHHHHHHHHHHSS?TTS?EE??H 1BS2|A PF00751.13_DM_seed 26 49 !Q:0,1|4,4|12,15|20,20|24,25|30,31|43,44|46,48 Q:2,3|5,11|16,19|21,23|26,29|32,42|45,45 ??SS?HHHHTTT?-??TTTT?GGG-?TTTT??SHHHHHHHHHH??S??? 1LPV|A PF00752.12_XPG_N_seed 10 111 !Q:0,2|13,13|28,30|47,47|49,49|55,55|57,57|61,61|63,63|81,81|88,93 Q:3,12|14,27|31,46|48,48|50,54|56,56|58,60|62,62|64,80|82,87|94,110 -??TTHHHHHHHH?GGGEEEEEGGGGTT--?EEEEEHHHHHHHHHHH?E-ETTEE?B?TTS?B?HHHHHHHHHHHHHHTTT?EEEEEE?????-GGGHHHHHHHHHHHHHH 3Q8K|A PF00753.22_Lactamase_B_seed 305 345 !Q:12,18|22,23|27,28|31,33|35,35|43,72|78,78|85,87|89,89|91,91|107,108|111,113|132,184|187,189|192,192|206,207|213,213|219,223|237,242|247,250|252,303|306,307|321,327|330,330|333,338|345,345 Q:0,11|19,21|24,26|29,30|34,34|36,42|73,77|79,84|88,88|90,90|92,106|109,110|114,131|185,186|190,191|193,205|208,212|214,218|224,236|243,246|251,251|304,305|308,320|328,329|331,332|339,344 ETTTTEEEEEEE?------TTT-?EEE--EE???S?HHHHHHH------------------------------HHHHT?EEEEEE--?S?S?HHHHTTHHHHHHHHT??EE???GGGHHHHHTHHHHHHHTT???--------------------------------------------??????SB???TT?EEEETTEEEEEEE??SSSTT?EEEEE-----TTTTEEEEETSEE------TTEE????S----------------------------------------------------TT??HHHHHHHHHHHTG-------GG?TT?-----EEEESS- 1JJE|A PF00754.20_F5_F8_type_C_seed 185 232 !Q:5,9|14,14|19,24|28,28|32,36|38,45|48,51|55,59|62,69|72,73|77,78|81,81|94,94|96,97|103,111|124,125|129,133|135,143|145,145|148,150|153,153|155,160|162,164|167,168|173,174|178,186|195,199|209,218|220,221|225,225 Q:0,4|10,13|15,18|25,27|29,31|37,37|46,47|52,54|60,61|70,71|74,76|79,80|82,93|95,95|98,102|112,123|126,128|134,134|144,144|146,147|151,152|154,154|161,161|165,166|169,172|175,177|187,194|200,208|219,219|222,224|226,231 GEEES?--??BGGG?GGGB----??GGG?BTT---??S--------SS---?SEE?----SS------??TT??EEE--EE-EEEEEEEEEEEE?E--EETTE---------EEEEEEEEEEEE--SSS-----S---------S?EE???TT?S------S???EE??SSSS??EEE---------EEEEEEEE-----EEEEEEEEE----------E--ESS?EEEEEE 3HNM|A PF00755.15_Carn_acyltransf_seed 17 759 !Q:2,8|19,19|26,26|28,28|46,46|64,69|71,71|85,87|89,89|96,96|98,99|103,108|111,119|144,158|163,183|186,188|201,205|208,210|212,212|217,217|223,228|243,243|245,245|247,248|251,251|253,254|269,270|272,273|275,278|286,286|303,304|317,317|322,345|355,355|360,368|370,370|372,372|375,377|383,384|394,394|398,398|404,404|408,409|420,422|430,468|472,476|479,479|506,506|508,509|516,516|519,520|536,536|541,543|550,550|556,557|562,565|576,585|587,589|593,593|597,609|632,633|648,652|655,660|662,664|675,677|679,680|684,688|691,692|694,696|700,700|704,709|714,714|722,723|726,726|737,737|740,741 Q:0,1|9,18|20,25|27,27|29,45|47,63|70,70|72,84|88,88|90,95|97,97|100,102|109,110|120,143|159,162|184,185|189,200|206,207|211,211|213,216|218,222|229,242|244,244|246,246|249,250|252,252|255,268|271,271|274,274|279,285|287,302|305,316|318,321|346,354|356,359|369,369|371,371|373,374|378,382|385,393|395,397|399,403|405,407|410,419|423,429|469,471|477,478|480,505|507,507|510,515|517,518|521,535|537,540|544,549|551,555|558,561|566,575|586,586|590,592|594,596|610,631|634,647|653,654|661,661|665,674|678,678|681,683|689,690|693,693|697,699|701,703|710,713|715,721|724,725|727,736|738,739|742,758 HS???????HHHHHHHHHH-HHTTTS?H-HHHHHHHHHHHHHHSTT-SHHHHHHHHHHHHHHTS------S?TTHHHHHHHHTTT??-S?SBTTTB?E--EEE??????SH---------HHHHHHHHHHHHHHHHHHHHHHTT??----------???BSSS---------------------SB???TTHHHHTTEEEE---??SS---S?EEEE?TTSSS?---??EEEEEETTEEEEEE?B?T--TS?B??HHHHHHHHHHHHHT??S??S--??GGGGGGS?HHHHHHHHHHHTTSHH--HHHHHHHHHHSS?EEEE?????----------------???HHHHHHHHH-HHHH---------T?S?TT---TTTTS??TTBSEEEEE?TTS?EEEEE?TTT??HHHHHHHHHH---HHHHHTS?---------------------????????----?????EEE?????HH-HHHHHHHHHHHHHHHHHHEEEEEEEE?S??THHHHH-TT??HHHHHHHHHHHHHHH-HHSS???EEEEEE?TTSTT??EEEE????HHHHHHHHHH----------T?--TTS?HHH-------------HHHHHHHHHHHHHHHHHHHHTT??SHHHHHHHHHHHHH-----TT????--H---HHHSHHHHHH---T??SEE-----EE--E???SSS?EEE---???SSTT?EEEEEEE?-SS?EEEEEEEETT?TT??HHHHHHHHHHHHHHHHH 2H3W|A PF00756.15_Esterase_seed 20 329 !Q:4,4|14,25|30,30|36,37|40,41|45,45|51,52|62,62|64,71|76,78|81,81|83,84|86,86|88,88|91,97|106,107|111,112|128,128|130,130|134,140|160,162|174,175|177,177|190,195|203,204|210,210|212,219|229,229|242,242|248,250|252,253|258,260|267,275|296,297|303,305|307,309|315,316 Q:0,3|5,13|26,29|31,35|38,39|42,44|46,50|53,61|63,63|72,75|79,80|82,82|85,85|87,87|89,90|98,105|108,110|113,127|129,129|131,133|141,159|163,173|176,176|178,189|196,202|205,209|211,211|220,228|230,241|243,247|251,251|254,257|261,266|276,295|298,302|306,306|310,314|317,328 ETTT-TEEEEEEEE----------??STTB?EEEEE??TT??SSS?HHHHH??HHHHHTTSS?E--------EEEE???TT?T--T?B?SS?------EEETTEEE??BHH--HHHHTHHHHHHHHHH?B?SSS-------EEEEEETHHHHHHHHHHHH--?TTTEEEEEEES??S?TTSTTHHHHHHH------HHHHTTS??HHHHH?S--------TTSTHHHHS?TTTTHHHHHHHT?EEEEE???S??BTTB??-SHHHHH---------HHHHHHHHHHHHHHHHHHTT??SEEEE??-S???SSHHH--HHHHHHHTHHHH 1F0N|A PF00757.15_Furin-like_seed 40 252 !Q:2,7|12,12|15,17|19,20|23,23|30,31|37,44|47,69|75,75|77,77|79,84|87,88|90,92|96,96|98,98|100,105|110,110|123,126|134,135|137,152|154,154|164,164|177,191|194,194|198,201|204,208|217,218|224,231|235,235|240,240|242,242|245,248 Q:0,1|8,11|13,14|18,18|21,22|24,29|32,36|45,46|70,74|76,76|78,78|85,86|89,89|93,95|97,97|99,99|106,109|111,122|127,133|136,136|153,153|155,163|165,176|192,193|195,197|202,203|209,216|219,223|232,234|236,239|241,241|243,244|249,251 SS??????TTTT-TT???S??EE-ETTEEE??EEETT--------EE?------------------????GGGTT-S?B?-----TT??B??-TTB?S?B------SSSS?TTSBSSBSSEEE----TTEEESS??T----------------T?EEETTTEEE?HHHHHHHHHHHH---------------HT?SSS????EE-----ETTEEESS??TTEEE?-------TTS?BEEE?S-SS-???EEE 3U2P|A PF00758.13_EPO_TPO_seed 6 166 !Q:1,1|5,5|26,26|31,32|34,37|39,40|43,44|52,52|82,84|87,88|110,110|113,118|120,120|124,125|128,131|133,134|162,162|165,165 Q:0,0|2,4|6,25|27,30|33,33|38,38|41,42|45,51|53,81|85,86|89,109|111,112|119,119|121,123|126,127|132,132|135,161|163,164 S?STT?HHHHHHHHHHHHHHHHHHTT?SSSS??S????B??TT??HHHHSSS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHS???SS??HHHHHHHHHHHHHHHHHHHHT?SS??????S?SST--TS????B??SSHHHHHHHHHHHHHHHHHHHHHHHHS?TT? 1EER|A PF00759.14_Glyco_hydro_9_seed 37 596 !Q:0,0|17,17|20,22|25,37|40,42|44,44|51,65|67,67|70,80|83,84|88,89|109,109|114,129|134,134|153,153|156,156|160,164|171,176|181,188|191,196|198,198|202,203|205,207|216,217|239,240|258,259|264,266|268,270|275,275|278,279|284,285|288,288|305,311|326,326|328,328|333,333|335,344|347,348|352,353|365,365|367,378|385,386|397,399|404,408|410,410|414,414|416,418|423,424|442,455|476,476|480,482|491,492|494,495|497,497|500,506|509,515|517,517|521,521|528,528|531,532|535,535|537,542|545,564|567,573|576,576|581,583|596,596 Q:1,16|18,19|23,24|38,39|43,43|45,50|66,66|68,69|81,82|85,87|90,108|110,113|130,133|135,152|154,155|157,159|165,170|177,180|189,190|197,197|199,201|204,204|208,215|218,238|241,257|260,263|267,267|271,274|276,277|280,283|286,287|289,304|312,325|327,327|329,332|334,334|345,346|349,351|354,364|366,366|379,384|387,396|400,403|409,409|411,413|415,415|419,422|425,441|456,475|477,479|483,490|493,493|496,496|498,499|507,508|516,516|518,520|522,527|529,530|533,534|536,536|543,544|565,566|574,575|577,580|584,595 ?HHHHHHHHHHHHHHTB?BS?-?TT??----------?TT???B?TTTTGG---------------G-TS-------????SB??SSS??EEHHHHHHHHHHHHHHHHH?HHHH----------------HHTT?HHHHHHHHHHHHHHHHHT?SB-TTB-----EEEEES?-----HHHH--------HH?----?S?GGG??S???EEEEBTTB??HHHHHHHHHHHHHHHHHHTTT-?HHHHHHHHHHHHHHHHH--HHHS???G---GGTS-TT--HHHH??SS?SHHHHHHHHHHHHHHH??-----HHHHHHHHHHGGGS?B?TTSS?B?--------?SS??SSS??HHHHHHHHHHH-H------?----?HHHHHH--HHHHHHHTTT?--BTTB--???B?TTS?B???SSSH--HHHHHHHHHHHHHHHHH??-----------?HHHHHHHHHHHHHHHHHHHT?STT???SBTTSSSS??S??S?HH-------HH-------T?SSS?TTSSSS?SS??TT?B???--?SS--------------------TT?-?????TT?TTTT???GGGGHHHHHHHH- 1IA7|A PF00760.13_Cucumo_coat_seed 4 210 !Q:0,37|43,48|52,56|63,66|69,74|77,77|83,86|92,92|107,107|110,113|120,122|126,128|141,143|147,149|154,156|158,159|163,163|167,167|176,176|186,188|202,207|209,209 Q:38,42|49,51|57,62|67,68|75,76|78,82|87,91|93,106|108,109|114,119|123,125|129,140|144,146|150,153|157,157|160,162|164,166|168,175|177,185|189,201|208,208 ??????????????????????????????????????HHHHH??????SSS?????SSSSEE????EE??????SS?EEEEE????TTTTT?TTSEEEEEEEEEEE?TT????EEEEEE???TTS???HHHHHHHHTSSS-??EEE???SSSS???S??EEE?TTT?EEHHHHTT?EEEEEESSS???TTSEEEEEEEEEE??????S? 1F15|A PF00762.14_Ferrochelatase_seed 217 571 !Q:0,0|8,11|15,16|26,28|31,32|34,34|38,43|45,51|53,53|67,67|77,78|80,81|83,86|88,89|109,109|112,132|134,134|136,137|147,147|153,153|163,163|165,166|168,173|182,182|185,186|205,222|226,229|232,232|235,237|240,240|251,254|262,262|264,264|266,274|280,289|297,298|303,303|307,307|309,340|342,378|388,391|395,395|399,438|440,444|447,447|449,464|471,474|477,478|480,480|497,497|499,503|510,510|512,512|515,519|524,524|536,541|546,548|552,552|560,562 Q:1,7|12,14|17,25|29,30|33,33|35,37|44,44|52,52|54,66|68,76|79,79|82,82|87,87|90,108|110,111|133,133|135,135|138,146|148,152|154,162|164,164|167,167|174,181|183,184|187,204|223,225|230,231|233,234|238,239|241,250|255,261|263,263|265,265|275,279|290,296|299,302|304,306|308,308|341,341|379,387|392,394|396,398|439,439|445,446|448,448|465,470|475,476|479,479|481,496|498,498|504,509|511,511|513,514|520,523|525,535|542,545|549,551|553,559|563,570 ?EEEEEEE????SSG--GGHHHHHHH---HT--T?TTT??---?S-------S?TTHHHHHHHHHHH-HHHHHHHTT--T--S----S??HHHHHHHHHHHHHHHHHHH?GG---------------------G?S--EEEEEEESS-SSSBH-HHHHHHHHH-T--T?-----SEEEEEES?SS??TTTHHHHHHHHHHHHHHH?--------------???SSE----EE-EE???TT?HHHHHHHHHH----HHHHHTT-S?T---------TTGGG---------?EEEEEEE??BHHH-HTT-T?-------------------------------S-------------------------------------HHHHHHHHH----HHH-HHH----------------------------------------T-----TT?S?---------------EEEEEE??-?SS--S?BSSSBHHHHHHHHHTT-T-?--?EEEEEE?S?SS?????HHHH?SHHHHHHHHHH??---?EEEE???STT?HHHHHHH---HHHHHHHH 1C9E|A PF00763.18_THF_DHG_CYH_seed 105 126 !Q:2,3|12,14|29,29|31,34|43,44|63,63|71,71|74,75|89,89|92,93|98,98|101,104|108,108|111,112|119,119 Q:0,1|4,11|15,28|30,30|35,42|45,62|64,70|72,73|76,88|90,91|94,97|99,100|105,107|109,110|113,118|120,125 EE??HHHHHHHH---HHHHHHHHHHHHHH-H????EEEEEEES??HHHHHHHHHHHHHHHHHT?EEEEEEE?TT??HHHHHHHHHHHHT?TT??EEEE?SS?--?TTS?HH--HHHHHS?GGGBTT 3L07|A PF00764.14_Arginosuc_synth_seed 12 406 !Q:3,4|21,22|34,38|51,51|59,59|76,77|83,84|106,106|111,114|131,131|134,134|138,138|142,142|149,152|164,167|170,172|175,175|179,179|182,182|186,186|196,198|202,203|206,207|212,212|215,215|234,235|238,239|242,242|244,245|262,263|271,271|275,275|283,283|294,294|303,303|317,317|326,326|346,347|366,366|369,373|378,383|385,386 Q:0,2|5,20|23,33|39,50|52,58|60,75|78,82|85,105|107,110|115,130|132,133|135,137|139,141|143,148|153,163|168,169|173,174|176,178|180,181|183,185|187,195|199,201|204,205|208,211|213,214|216,233|236,237|240,241|243,243|246,261|264,270|272,274|276,282|284,293|295,302|304,316|318,325|327,345|348,365|367,368|374,377|384,384|387,405 EEE??SSHHHHHHHHHHHHTT--EEEEEEEEESS??-??HHHHHHHHHHHT?SEEEEEE?HHHHHHHTHHHHHHTT??BTTTB??TTTTHHHHHHHHHHHHHHHHT?SEEE????TTSSHHHHHHHHHHHH?TT?EEE?GGG?HHHHTT????HHHHHHHHHTT????SS???SS?EEE?SS?EEE?SGGGGSTTS???GGG??SS??TTTS?SS?EEEEEEEETTEEEEEEET--TT??EE?S--HHHHHHHHHHHHHHHT??EEEEEEE?TTS?EEEEEEE?HHHHHHHHHH-HHHHHHHS?HHHHHHHHHHHHH-HHHHHHHT?SSSHHHHHHHHHHHHHTTT??EEEEEEEETTEEEEEEEE?TT?-???HHHH??????S??HHHHHHHHHHHHHHHHHHH 2NZ2|A PF00765.12_Autoind_synth_seed 13 188 !Q:4,24|35,38|41,41|45,45|54,54|69,70|74,74|85,87|90,92|101,101|104,104|111,112|115,116|134,134|153,157|169,169|178,178 Q:0,3|25,34|39,40|42,44|46,53|55,68|71,73|75,84|88,89|93,100|102,103|105,110|113,114|117,133|135,152|158,168|170,177|179,187 EGGG??????-??????????????HHHHHHHTTS????TT?STT?EEEEEEET-TEEEEEEEEEETTS??III-IITHHHHTTS???SS?--EEEEEEEE?HH-HHHHHH?-TT??HHHHHHHHHHHHHHHTT?SEEEEEEEHHHHHHHHHT?-???EEEEEEESSSS?EEEEEEEE?SHHHHHHHH 3P2F|A PF00766.14_ETF_alpha_seed 39 102 !Q:1,3|7,7|14,14|18,18|20,21|27,28|38,38|40,40|45,45|51,60|65,65|76,79|87,90|100,100 Q:0,0|4,6|8,13|15,17|19,19|22,26|29,37|39,39|41,44|46,50|61,64|66,75|80,86|91,99|101,101 S??-GGG?SEEEEE?GGG?S--TGGGH--HHHHHHHHH-T?EEEE?HHHHH----------TTSS?GGGBBSTTSB????SEEEEES????HHHHTTTTT?S 1O97|D PF00768.15_Peptidase_S11_seed 12 280 !Q:0,19|31,32|41,42|44,45|67,67|70,70|74,75|79,79|90,95|98,98|113,114|130,135|151,151|154,154|156,158|161,162|164,164|167,181|184,184|199,200|209,210|216,225|231,231|233,233|238,238|251,251|255,255|266,266 Q:20,30|33,40|43,43|46,66|68,69|71,73|76,78|80,89|96,97|99,112|115,129|136,150|152,153|155,155|159,160|163,163|165,166|182,183|185,198|201,208|211,215|226,230|232,232|234,237|239,250|252,254|256,265|267,279 ????????---------???SSEEEEEETTT??EEEEESTT??B??GGGHHHHHHHHHHHHHHTTSS?TT?EEE??GGG?TTTSGGGTTS??????TT?EEEHHHHHHHHHTT??HHHHHHHHHHHHSSH------HHHHHHHHHHHHHHT?TT?B???SS??S?TT?--------------BB?HHHHHHHHHHHHHH-?HHHHHGGG??EEEET----------TEEEE?S?GGGG?SSSEEEEEEEEE?SSS?EEEEEEEEET-TEEEEEEEEEESS 1ES5|A PF00769.14_ERM_seed 10 298 !Q:33,111|126,128|133,154|159,193|199,203|205,208|210,212|217,228|233,233|252,252|256,258|268,268|273,274|284,284|286,286|297,297 Q:0,32|112,125|129,132|155,158|194,198|204,204|209,209|213,216|229,232|234,251|253,255|259,267|269,272|275,283|285,285|287,296 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH???????????????????????????????????????????????????????????????????????????????HHHHHHHHHHHHHH---HTTS--------------------??GGGS????-------------????--????????????EEEEE?????T----T???GGGG??---------?HHHH?HHHHHHHHHHHHHHHTTB?GGG-??HHHHHHHHH-HHTT??HHHHHHHHT?S?HHHHHHHHHT? 1EF1|C PF00770.13_Peptidase_C5_seed 13 183 !Q:6,6|9,14|18,18|27,27|32,32|34,34|51,51|54,56|65,68|80,80|91,91|94,94|96,96|99,101|116,116|120,120|131,132|140,140|162,162|177,177|182,182 Q:0,5|7,8|15,17|19,26|28,31|33,33|35,50|52,53|57,64|69,79|81,90|92,93|95,95|97,98|102,115|117,119|121,130|133,139|141,161|163,176|178,181 GEEEEE?TT??????SSS?EEEEEESS?TTTT?S?EEEEEEETTTTEEEEE?TT???HHHHHHHH????HHHHHHHHHHH?TTSEEEEEEE?EE?S?TT???HHHHHHHHHHHHHH?TTS?SSSSTTGGGS??EEGGGTT?TTTHHHHHHHHHHHHHHHHHH?HHHHTTHHHHHHHS?TTTT? 1AVP|A PF00771.15_FHIPEP_seed 180 830 !Q:0,366|375,388|390,392|402,407|414,414|426,431|449,454|459,460|464,464|468,471|486,487|490,491|493,575|577,577|598,599|611,618|622,622|630,630|635,636|652,656|669,669|672,675|693,696|700,701|703,705|707,707|709,709|712,712|716,716|728,745|747,749|757,758|767,769|772,772|776,783|786,790|794,794|809,810|812,812|814,815|823,823|826,828 Q:367,374|389,389|393,401|408,413|415,425|432,448|455,458|461,463|465,467|472,485|488,489|492,492|576,576|578,597|600,610|619,621|623,629|631,634|637,651|657,668|670,671|676,692|697,699|702,702|706,706|708,708|710,711|713,715|717,727|746,746|750,756|759,766|770,771|773,775|784,785|791,793|795,808|811,811|813,813|816,822|824,825|829,829 ---------------------------------------------------------------------???------------------------------------------------------------------------------------------------------------------------------------------------?????------------------------????-???-------------------------------------------------------------------------------------------------------------?????HHHHHHHH--------------S???SHHHHGGGS???---SEEEEE?GGGHHHHHSSS--???-HHHHHHHHHHHHHHHHS??????EEEE?-TTS?TTE----EEEEETTEEEEEEE??TT??B???--????-??----------------??-??--????-----????????????????????????-------------??B?HHHHHHHHHHHHHHHHHHHH??HHHHHHHHHHH--------HHH?HHHHHHH-TTTT??HHHHHHHHHHHHHTT?????HHHHHHHHHHHT-TT?-??HHHHHHHHHHHTHHHHH----HHH??T---T-S?EE?BEE?HHHHHHHHHHB-??-????-?-------?B???HHHHHHH--HHHHHHHH---HH-HHH--------TT????-EEE?HHHHHHHHHHHTTT?-T-T??EEEGGGS?TT?-?E 2X49|A PF00772.16_DnaB_seed 156 132 !Q:0,3|5,7|9,9|22,26|29,30|39,44|68,73|83,87|96,96|98,98|112,112|114,116|119,120|127,127|131,131 Q:4,4|8,8|10,21|27,28|31,38|45,67|74,82|88,95|97,97|99,111|113,113|117,118|121,126|128,130 ????H---H-HHHHHHHHHHHH--?--GG--GHHHHHTT?-?---GGGSSSHHHHHHHHHHHHHHHTT---???SHHHHHHHH-----HTTTTHHH-H-THHHHHHHHHHHS?S---SS-?HHHHHH-HHH? 2VYF|A PF00773.14_RNB_seed 86 700 !Q:0,0|3,5|9,18|20,20|24,24|27,28|30,36|40,55|60,60|62,62|65,93|102,102|108,108|111,118|124,124|130,130|132,157|164,164|167,167|170,170|175,176|178,181|186,187|191,228|230,230|241,242|245,245|247,254|256,256|259,261|286,286|289,291|294,329|338,341|343,343|356,364|366,372|375,378|381,413|418,439|441,446|448,452|455,480|502,508|512,514|518,518|524,527|530,537|540,540|547,569|576,580|593,595|597,603|605,605|613,619|628,633|642,642|647,661|668,671|674,677|679,679 Q:1,2|6,8|19,19|21,23|25,26|29,29|37,39|56,59|61,61|63,64|94,101|103,107|109,110|119,123|125,129|131,131|158,163|165,166|168,169|171,174|177,177|182,185|188,190|229,229|231,240|243,244|246,246|255,255|257,258|262,285|287,288|292,293|330,337|342,342|344,355|365,365|373,374|379,380|414,417|440,440|447,447|453,454|481,501|509,511|515,517|519,523|528,529|538,539|541,546|570,575|581,592|596,596|604,604|606,612|620,627|634,641|643,646|662,667|672,673|678,678|680,699 ?EE?--TTS--------??E-EEE?TT-?S?----??EEE----------------EEEE?T-TS?----------------------------EEEEEEEE?HHHHS?SS--------SHHHH-HHHHH?B-------------------------?EEETTE-EE?SS?HHHH--T----TTSS??BTS--------------------------------------E-EEEEEEEEEE-?TT-S?-------E-EE---EEEEEEEEEBSEEEEHHHHHHHHH?TT???HH------------------------------------HHHHHHHH----H-HHHHHHHHHHTT---------T????-?-SH----HH---------------------------------HTTS--------------------??T------T?????SS???---------------------??HHHHHHHHHHHHHHHHHHHHH-------HHH?--TTT?EEEEB????GG--------GG-HHHHHH-----------------------HHHHHS?????SSHHHHHHHHHH???S-------S?TTHHHHH-------HHHHHTTS---???EEEEGGGS?GGGS---?-----------BTTTTB----SS????S?TTTBHHHHHHHHHHHHHTTS 2R7D|A PF00775.16_Dioxygenase_C_seed 20 231 !Q:0,2|4,5|8,13|18,18|22,24|26,28|31,32|42,42|46,46|48,48|51,51|57,59|63,64|68,68|71,75|81,82|87,88|99,102|105,106|118,118|121,123|126,126|135,135|139,141|151,151|156,158|161,169|172,172|175,176|180,180|183,205|213,213|216,217|223,224|227,228|230,230 Q:3,3|6,7|14,17|19,21|25,25|29,30|33,41|43,45|47,47|49,50|52,56|60,62|65,67|69,70|76,80|83,86|89,98|103,104|107,117|119,120|124,125|127,134|136,138|142,150|152,155|159,160|170,171|173,174|177,179|181,182|206,212|214,215|218,222|225,226|229,229 ???S??EE?---??EEES-EEE???S?-?TT??EEEEEEEEE?TTS?B?TT?EEEEE???TTS??TTS?TT????-TTTTE--EEEE??TTSEEEEEEE????EE??TTSHHHHHHHH-TT???EE?SEEEEEEE?TTB-??EEEEEEETT?TTTT-??TT??-----??TT?EE??EEE?SH-----------------------HHHHHTT?SS?-EEEEE??EE??B? 3T67|A PF00777.13_Glyco_transf_29_seed 105 387 !Q:0,0|3,7|9,10|14,17|19,20|29,29|32,33|36,39|50,55|57,57|59,59|61,63|71,74|76,77|83,84|91,93|109,111|114,115|120,120|122,123|133,152|155,155|160,163|179,190|196,197|199,203|208,248|252,252|254,261|275,285|289,300|313,313|316,316|322,322|324,331|335,337|341,356|360,360|372,372|377,378|384,386 Q:1,2|8,8|11,13|18,18|21,28|30,31|34,35|40,49|56,56|58,58|60,60|64,70|75,75|78,82|85,90|94,108|112,113|116,119|121,121|124,132|153,154|156,159|164,178|191,195|198,198|204,207|249,251|253,253|262,274|286,288|301,312|314,315|317,321|323,323|332,334|338,340|357,359|361,371|373,376|379,383 ?TT???--B??TTT????H--HHHHHHHH-HH??SS?-??HHHHHHHHTT------T-S?S???TTTTGGG---?S??EEEEE??BGGGTT???HHHHHTSSEEEEETT???TT-?HHHH?S??SEEEEBTTB???---------------??TT?EEEE??--SSHHHHHHHHHHTTT?-------?-??BSSSB??S?????GGGE-----------------------------------------EEB?H--------HHHHHHHHHTSTT----------?SSS??----------HHHHHHHHHHHH?SE-EEEES?S?------?TTS???BTT--??--??????????SSS?HHHHHHHHHHH-HHTT--SSEEE??? 2WNF|A PF00778.12_DIX_seed 25 93 !Q:0,2|9,9|13,13|16,16|25,28|37,39|41,42|44,44|53,53|66,67|70,70|72,76|85,87|91,92 Q:3,8|10,12|14,15|17,24|29,36|40,40|43,43|45,52|54,65|68,69|71,71|77,84|88,90 ???EEEEEE-ETT?SS?EEEEETTS?--?BHHHHHHH?-?S?-S?EEEEEEEE?TTSTTSEEEEEE??TT?B?--??BTTBEEEE---EEE?? 1WSP|A PF00779.14_BTK_seed 26 34 !Q:0,0|3,3|6,6|8,10|18,19|21,21|24,27|30,31 Q:1,2|4,5|7,7|11,17|20,20|22,23|28,29|32,33 ?EE?SS?B?--SSSBSSS??S?TT????EE??SS 1BWN|A PF00781.19_DAGK_cat_seed 125 272 !Q:6,6|10,11|14,15|21,23|30,30|32,33|37,38|40,40|43,48|50,51|54,54|57,62|64,65|70,71|74,79|83,84|87,87|91,105|112,112|126,136|138,140|142,151|154,172|174,176|182,182|185,186|194,196|202,245|254,255|262,264 Q:0,5|7,9|12,13|16,20|24,29|31,31|34,36|39,39|41,42|49,49|52,53|55,56|63,63|66,69|72,73|80,82|85,86|88,90|106,111|113,125|137,137|141,141|152,153|173,173|177,181|183,184|187,193|197,201|246,253|256,261|265,271 EEEEEE?TTS--TT??HHHHH---HHHHHH-H--HHT--T-EE------E--EE-EE?--?--S--TTHH--HH------HHH--HH-TTS?-------------?SEEEEE-ESHHHHHHHHHHH-----------T---T------?---TT-----------------??E---EEEEE?SS??HHHHHHT?-?SSHHH--------------------------------------------HHHHHHHT-?EEEEEE---EEETTEE 2QVL|A PF00782.15_DSPc_seed 24 168 !Q:10,12|21,22|27,27|30,45|48,48|56,60|62,71|76,77|90,90|93,95|100,101|126,129|138,143|147,148|151,154 Q:0,9|13,20|23,26|28,29|46,47|49,55|61,61|72,75|78,89|91,92|96,99|102,125|130,137|144,146|149,150|155,167 EEEEEHHHHT--?HHHHHHHT??EEEE?SS????------------TT?TTSEEEE??-??S----------STTS??GGGHHHHHHHHH-HH---HHTT??EEEEESSSSSHHHHHHHHHHHHHH??-?HHHHHHHH------HHH?-TT????HHHHHHHHHHHHH 1I9T|A PF00784.12_MyTH4_seed 11 120 !Q:0,1|16,16|34,38|56,59|68,68|75,75|77,85|102,106|109,111 Q:2,15|17,33|39,55|60,67|69,74|76,76|86,101|107,108|112,119 ??HHHHHHHHHHHHHH?GGGHHHHHHHHHHHTSS???--HHHHHHHHHHHHHHHHH????TTTHHHHH-HHHHTS?T---------TTHHHHHHHHHHHHHH?--??SS???HHHHHHHH 3PZD|A PF00786.23_PBD_seed 44 74 !Q:0,6|25,29|31,32|43,54|61,61 Q:7,24|30,30|33,42|55,60|62,73 ?????-?SSEEEEEEEEETTTTEEE-----S??HHHHHHHHTS---------???HHHHHH?HHHHHHHHHHHH 1T84|A PF00787.19_PX_seed 71 208 !Q:1,2|5,6|11,23|27,28|36,37|39,46|50,50|58,58|73,166|173,173|192,197|206,207 Q:0,0|3,4|7,10|24,26|29,35|38,38|47,49|51,57|59,72|167,172|174,191|198,205 S??EE--EEEE?????----????GGG??EEEEEEE??T--------TSS?SEEEEEE?HHHHHHHHHHHHHH??----------------------??????????----??????---------------------------------------???????????HHHHHH-HHHHHHHHHHHHSHHHHT-----?HHHHHHHH?? 3HPB|A PF00788.18_RA_seed 54 135 !Q:0,0|8,14|16,26|35,36|51,56|67,77|81,93|98,99|102,103|111,114|116,121|123,124 Q:1,7|15,15|27,34|37,50|57,66|78,80|94,97|100,101|104,110|115,115|122,122|125,134 ?EEEEEEE???????S---------??EEEEEETT??HHHHHHHHHHHTTS-----?GGGGGGEEEE-----------EEE?????????????EEEE??TT??HHHHHHH????T------T??EEEEEEEHHH 3TCA|A PF00789.15_UBX_seed 22 114 !Q:0,4|12,12|16,16|24,24|41,42|45,48|50,74|83,84|92,92|101,101|103,104 Q:5,11|13,15|17,23|25,40|43,44|49,49|75,82|85,91|93,100|102,102|105,113 ?????EEEEEEE?TTS?EEEEEEE-TTSBHHHHHHHHHHTT??TT----T-------------------------EEEEEETT--EEEGGGS?TTSBTTTT-T??SEEEEEEEE 2DZK|A PF00790.14_VHS_seed 15 155 !Q:0,5|15,15|18,18|21,24|38,42|59,61|103,103|112,112|130,137|140,140 Q:6,14|16,17|19,20|25,37|43,58|62,102|104,111|113,129|138,139|141,154 ??????HHHHHHHHH?TT?SS?--?HHHHHHHHHHHHH?----TTHHHHHHHHHHHHHT?--SSHHHHHHHHHHHHHHHHHSHHHHHHHHTSHHHHHHHHHHH?TTTTGGGS?HHHHHHHHHHHHHHHHH?-------TT?HHHHHHHHHHHHTT 1JWG|A PF00791.15_ZU5_seed 30 150 !Q:0,0|9,9|12,12|17,17|28,28|33,33|36,37|45,50|55,87|91,93|98,98|101,101|103,104|109,109|112,114|117,117|124,125|127,128|130,130|132,133|135,139 Q:1,8|10,11|13,16|18,27|29,32|34,35|38,44|51,54|88,90|94,97|99,100|102,102|105,108|110,111|115,116|118,123|126,126|129,129|131,131|134,134|140,149 ?TTEEEEEE?TT?EEEE-ETTTTEEEEE?TTSS?TT??EEEEEEE??----GGGG---------------------------------GGG--?STTE-EE?S??EEEE?SS???SS?EEEEEE??B??S-S--S?---?EEEEEEESST 4D8O|A PF00792.19_PI3K_C2_seed 24 194 !Q:0,2|12,14|22,27|29,29|31,33|37,46|49,49|53,53|60,60|66,67|70,70|78,82|85,108|120,120|122,122|127,129|136,137|140,174|178,178|181,182|184,184|189,189 Q:3,11|15,21|28,28|30,30|34,36|47,48|50,52|54,59|61,65|68,69|71,77|83,84|109,119|121,121|123,126|130,135|138,139|175,177|179,180|183,183|185,188|190,193 ???EEEEEEEEE---ETTEESS----??E-E???EES?---------SS?EEE-EEEEEE-EETTT??TT?EEEEEEE-----EE??????????------????????EEEEEEEEESB?T-TSBB??-EEEEEE?-EE??????????------------------------?TTS?SS??S?TTTS?EEEE 4FLH|A PF00793.15_DAHP_synth_1_seed 28 343 !Q:2,4|26,28|35,35|38,40|68,76|81,83|87,87|93,95|113,113|116,117|122,124|135,135|141,141|147,147|157,157|160,160|165,166|169,170|184,185|191,191|202,204|206,206|212,213|216,216|218,220|237,246|251,251|259,270|289,290|300,300|306,307|310,316|318,318|320,322|325,325|330,330|333,333 Q:0,1|5,25|29,34|36,37|41,67|77,80|84,86|88,92|96,112|114,115|118,121|125,134|136,140|142,146|148,156|158,159|161,164|167,168|171,183|186,190|192,201|205,205|207,211|214,215|217,217|221,236|247,250|252,258|271,288|291,299|301,305|308,309|317,317|319,319|323,324|326,329|331,332|334,342 HS???HHHHHHHHHHHHHHHHHHTTS???EEEEEE?SS???HHHHHHHHHHHHHHHHHTTTTEEEEEE??????--?SSSS???TTT?TTSSS???HHHHHHHHHHHHHHHHH-TT??EEEE???SSTHHHHGGG?SEEEE?TTTTT?HHHHHHHHT?SS?EEEE??TT??SHHHHHHHHHHTS??EEEEE?TTSBEEEEEE???S?EEEEE??SS-S???SHHHHHHHHHHHHHTT???------?EEEE?SGGGTTT?-----------GGGHHHHHHHHHHHHHTT??SEEEEEEEB?SSSBB??SS-------S?S???TT?BSSS?BB?HHHHHHHHH 3QQ0|A PF00794.13_PI3K_rbd_seed 12 129 !Q:1,5|24,25|27,32|36,37|49,49|61,62|68,70|94,94|97,98|100,102|117,119 Q:0,0|6,23|26,26|33,35|38,48|50,60|63,67|71,93|95,96|99,99|103,116|120,128 S?????HHHHTTTSTTEEEEEEEE??T------TTT??EEEEEEEETTS?HHHHHHHHHHH--HHHTS???HHHHHHHHHHHGGGEEEEETTSS?EE?-S???GGGBHHHHHHHHHT???EEEEEEHHH 4FLH|A PF00795.17_CN_hydrolase_seed 58 419 !Q:6,20|23,23|28,28|37,66|73,74|76,76|78,78|82,83|85,87|92,92|94,111|113,113|121,121|123,139|142,145|155,229|236,237|243,243|248,253|258,262|274,278|280,280|283,292|294,294|298,298|301,311|314,318|323,323|325,336|338,338|340,341|345,351|353,353|355,359|364,376|380,381|391,391|395,407|410,410|418,418 Q:0,5|21,22|24,27|29,36|67,72|75,75|77,77|79,81|84,84|88,91|93,93|112,112|114,120|122,122|140,141|146,154|230,235|238,242|244,247|254,257|263,273|279,279|281,282|293,293|295,297|299,300|312,313|319,322|324,324|337,337|339,339|342,344|352,352|354,354|360,363|377,379|382,390|392,394|408,409|411,417 EEEEEE--------???---?TT?HHHH-HHHHHHHH------------------------------HHHHHT--T?S-EEE??T---TTTT?S??----------------S?HHHHHHH?B----------------?TT----TSHHHHHHH---------------------------------------------------------------------------HHHHHH??EEEEE-EEEE------ETTE-----EEEEEEEEETT-----E-EE----------E-EEE?SS?---------?GG-----GGGT?B??---------?S?S-?EEE?------S-S----?EEEE--??---------GGG--GGSHHHHHH-HHH-------------TT?SEEEEEE? 1FO6|A PF00796.13_PSI_8_seed 36 25 !Q:0,1 Q:2,24 ??TTTTIIIIIHHHHHHHHHTTTTT 2WSE|I PF00797.12_Acetyltransf_2_seed 33 287 !Q:16,16|19,19|26,36|49,51|53,53|70,70|88,89|92,93|100,100|106,107|112,112|114,116|119,119|121,122|125,125|128,129|132,132|136,136|139,140|145,145|151,154|162,163|167,167|169,169|175,175|178,181|190,193|195,195|204,204|210,210|213,214|220,222|228,228|231,231|248,248|254,254|261,262|275,278|280,282|284,286 Q:0,15|17,18|20,25|37,48|52,52|54,69|71,87|90,91|94,99|101,105|108,111|113,113|117,118|120,120|123,124|126,127|130,131|133,135|137,138|141,144|146,150|155,161|164,166|168,168|170,174|176,177|182,189|194,194|196,203|205,209|211,212|215,219|223,227|229,230|232,247|249,253|255,260|263,274|279,279|283,283 SHHHHHHHHHHHHHHS?EE?TTGGGT-----???-??SHHHHHHHHHTT???B?HHHHHHHHHHHHHHHT?EEEEEEEEEEETTTTEE-?SS??EEEEEE-EETTE--EEEE?S???GG-G??SS?EE??TT?EEE?SS?-EEEE-EEETT----EEEEEEE??EEE?S?GGGTT?TT????SEEEEEEE????B?GGGGHHHH-HHHHH?TT?-HHHHB--?EEEEE?SS-EEEEEETTEEEEEETT?SSSEE-EEEEEE??HHHHHHHHHHHH????S---S??? 1W5R|A PF00798.13_Arena_glycoprot_seed 20 549 !Q:0,370|418,418|425,425|427,429|432,447|450,452|455,464|480,548 Q:371,417|419,424|426,426|430,431|448,449|453,454|465,479 -------------------------------------------------------------?---------------------------------------------------------------------------------------------------------------------------------?---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?GGGTTS?B???SS????????????????SB???TT??????????HHHHHHHHHHHHHHH????????????????------------------------------------------------????? 2WFO|A PF00799.15_Gemini_AL1_seed 11 120 !Q:0,2|14,17|28,30|33,33|36,36|45,45|49,49|64,66|71,71|74,74|78,78|80,80|83,84|90,90|92,92|101,102|104,107|109,109|114,119 Q:3,13|18,27|31,32|34,35|37,44|46,48|50,63|67,70|72,73|75,77|79,79|81,82|85,89|91,91|93,100|103,103|108,108|110,113 ???EEEEEEEEETT????HHHHHHHHHH???SS?EE-EEEEEEEE?TTS?EEEEEEEEEEEEEE???TTSS?EE?SSS-S?EE??EEEEE?S?THHHHHHH??S----S?EEES?????? 1L2M|A PF00800.13_PDT_seed 134 315 !Q:5,5|16,19|23,33|40,40|43,57|68,72|84,85|87,87|89,89|97,98|101,101|103,104|106,123|132,134|137,139|144,144|147,176|178,179|182,184|186,193|197,197|211,215|220,221|225,225|227,227|235,237|241,260|263,263|266,270|276,276|284,284|286,287|293,293|295,295|298,302|314,314 Q:0,4|6,15|20,22|34,39|41,42|58,67|73,83|86,86|88,88|90,96|99,100|102,102|105,105|124,131|135,136|140,143|145,146|177,177|180,181|185,185|194,196|198,210|216,219|222,224|226,226|228,234|238,240|261,262|264,265|271,275|277,283|285,285|288,292|294,294|296,297|303,313 EEEES?TTSHHHHHHH----HHS-----------EEEEES?HH---------------HHHHHHHTTS---?-SEEEEEEEESS--S?B?HHHHHHH--HH-S--S------------------EEEEEEEE---EE???EEEE?SS?----------------------------?T--TT-??E--------EEE?HHHHHHTHHHHHH?----TTSE--EEE?S?HHHHHHH---HHH--------------------TT?TT-----EEEEE?HHHHHHT-T?-EEEES-S?SS??-??EEEEEEEEETT? 3LUY|A PF00801.15_PKD_seed 93 142 !Q:0,2|4,8|18,18|23,23|26,26|28,28|31,46|48,48|54,57|60,60|63,85|87,87|97,98|101,123|138,138 Q:3,3|9,17|19,22|24,25|27,27|29,30|47,47|49,53|58,59|61,62|86,86|88,96|99,100|124,137|139,141 ???E-----EESEEETTS?EEEE?TT?B?SS----------------S?EEEEE----EE?SS-----------------------S?EEESSEEEE??SS----------------------?EEEEEEEEEEETTS?EEE 2C26|A PF00804.20_Syntaxin_seed 171 197 !Q:5,9|29,29|36,39|45,45|48,51|53,85|101,103|106,112|121,129|131,136|141,152|155,165|172,174|185,185|197,197 Q:0,4|10,28|30,35|40,44|46,47|52,52|86,100|104,105|113,120|130,130|137,140|153,154|166,171|175,184|186,196 HHHHH-----HHHHHHHHHHHHHHHHHHH-HHHHHH----HHHHH?SS--??H---------------------------------HHHHHHHHHHHHHHH---HH-------HHHHHHHH---------H------HHHH------------HH-----------HHHTTS???HHHHHHHHHH-HHHHHHHHHHH- 1FIO|A PF00805.17_Pentapeptide_seed 95 40 !Q:0,0|2,2|5,5|7,7|10,10|12,12|15,15|17,17|20,20|22,22|25,25|27,27|30,30|32,32|35,35|37,37 Q:1,1|3,4|6,6|8,9|11,11|13,14|16,16|18,19|21,21|23,24|26,26|28,29|31,31|33,34|36,36|38,39 ?B?TT?B?TT?B?TT?B?TT?B?TT?B?TT?B?TT?B?TT 2O6W|A PF00806.14_PUF_seed 50 37 !Q:11,11|26,26|28,28 Q:0,10|12,25|27,27|29,36 HHTTTHHHHHT-STTHHHHHHHHHHH-S?TTTSHHHH 3Q0M|A PF00808.18_CBFD_NFYB_HMF_seed 28 69 !Q:2,3|16,16|19,19|21,22|24,24|48,48|56,57|60,60 Q:0,1|4,15|17,18|20,20|23,23|25,47|49,55|58,59|61,68 GS??HHHHHHHHHHTS?TT?E--E?HHHHHHHHHHHHHHHHHHHHHHH-HHHHHTT??EE?HHHHHHHH 2YFW|B PF00809.17_Pterin_bind_seed 42 289 !Q:3,15|20,20|25,34|43,43|50,69|90,101|103,105|111,111|113,113|124,124|126,127|136,136|138,145|157,159|165,166|171,171|181,194|201,201|222,223|225,225|232,233|235,236|239,240|242,243|257,265|270,273|276,276|281,281|284,284 Q:0,2|16,19|21,24|35,42|44,49|70,89|102,102|106,110|112,112|114,123|125,125|128,135|137,137|146,156|160,164|167,170|172,180|195,200|202,221|224,224|226,231|234,234|237,238|241,241|244,256|266,269|274,275|277,280|282,283|285,288 EEE?????????????HHHH-HHHH----------HHHHHHTT?SEEEEE????--????---------?HHHHHHHHHHHHHHHHHHHH------------H???EEEEE?S?HHHHHHHHHT-T??EEEETTTT?S-------?TTHHHHHHHHT?--EEEEE??HHHH?TTSTTTTTS??????????????HHHHHS?HHHHHHHHHHHHHHHHHHHT??G-GGEEEE??T--TS--S??HHHHHHHHHTHHH---------HHTT----SS?BEEE?SS?HHHH 3TYA|A PF00812.12_Ephrin_seed 14 176 !Q:0,4|10,10|14,14|20,20|22,22|28,28|37,53|58,59|66,66|74,76|78,78|87,88|91,91|94,114|116,117|124,124|126,127|129,129|133,136|139,139|145,146|151,153|155,163|170,175 Q:5,9|11,13|15,19|21,21|23,27|29,36|54,57|60,65|67,73|77,77|79,86|89,90|92,93|115,115|118,123|125,125|128,128|130,132|137,138|140,144|147,150|154,154|164,169 ?????EEEEE?STT?GGGTT-S?EEEEE?TTEEEEEE?????????-------?TTTS??EEEEEE?HHHHHHT??-S?GGGEEEEE??TT?SS---------------------S??EEEEEE?S??S?TTS????TT?EEEEE??BSSS???S-------??EEEEEE?????? 3MBW|B PF00814.20_Peptidase_M22_seed 113 390 !Q:9,9|17,18|20,20|22,23|47,49|51,52|55,56|58,59|69,69|89,91|109,110|113,119|122,129|136,136|139,139|148,148|160,167|169,170|184,185|187,193|195,197|200,201|209,209|212,212|216,218|220,225|228,228|231,231|233,240|242,242|244,245|247,250|263,265|267,268|272,285|313,322|324,325|329,330|336,337|341,341|347,353|362,365|368,369|373,375|378,378|383,383 Q:0,8|10,16|19,19|21,21|24,46|50,50|53,54|57,57|60,68|70,88|92,108|111,112|120,121|130,135|137,138|140,147|149,159|168,168|171,183|186,186|194,194|198,199|202,208|210,211|213,215|219,219|226,227|229,230|232,232|241,241|243,243|246,246|251,262|266,266|269,271|286,312|323,323|326,328|331,335|338,340|342,346|354,361|366,367|370,372|376,377|379,382|384,389 EEEEEEEEE?HHHHHTT--T-S??HHHHHHHHHHHHHHHHHHHHHHH---T??GG--G??EEEEEEESS?HHHHHHHHHHHHHHHHHHT??-EEEEEHHHHHHHGGGGS--SS?-?---?SS--------EEEEEE?SS?EEEEEEEE-TTEEEEEEEBS--------S??HHHHHHHHHHHTT??S-------S--?HH--HHHHHHT-TS?TTS---S?--???TT?SS?S--------S?B??H----HHHHHHHHHHHT---S??SHH--------------HHHHHHHHHHHHHHHHHHHHHHHHHHH----------H??SEE--EEESG--GGG?HHHHH-------HHHHHHHH----TT-?EEE???GG-GTSS?SHHHHH 2IVP|A PF00815.15_Histidinol_dh_seed 16 439 !Q:5,12|43,49|51,51|53,54|56,57|69,69|91,96|114,114|121,123|127,128|144,144|152,152|155,162|174,175|180,181|192,194|197,200|202,204|209,211|229,229|231,231|234,239|246,246|250,250|265,265|268,268|276,278|296,296|298,299|301,301|303,303|311,312|314,314|319,319|333,334|347,347|352,355|364,365|376,381|388,392|406,406|426,426 Q:0,4|13,42|50,50|52,52|55,55|58,68|70,90|97,113|115,120|124,126|129,143|145,151|153,154|163,173|176,179|182,191|195,196|201,201|205,208|212,228|230,230|232,233|240,245|247,249|251,264|266,267|269,275|279,295|297,297|300,300|302,302|304,310|313,313|315,318|320,332|335,346|348,351|356,363|366,375|382,387|393,405|407,425|427,438 HHHHT????????HHHHHHHHHHHHHHHHHHHHHHHHHHHSSS--???-?S?S--B??HHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHTT?--???EEEEEETTEEEEEEEEE?SEEEEE???SSS??HHHHHHHHHHHHHHT?SEEEEEE?SS-?-----?HHHHHHHHHTT??EEEE??HHHHHHHHHH?-?SS----S???SEEE???SHHHHHHHHHHHHSTTS?E-ES??????EEEEEE?TTS?HHHHHHHHHHHHTT?TT?EEEEEES?--HHHHHHHHHHHHHHHHT?S--S?H-HHHHHHT--T?EEEE?SSHHHHHHHHHHH??SEEEEESTTHHH-HGGG????SEEEESTT??HHHHHHTSSS??????TTGGGT?????GGGGEEEEEEEEE?HHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHH 1K75|A PF00816.16_Histone_HNS_seed 151 160 !Q:0,25|27,39|41,53|55,85|88,105|111,115|119,119|123,124|126,127|133,136|158,158 Q:26,26|40,40|54,54|86,87|106,110|116,118|120,122|125,125|128,132|137,157|159,159 ---------??---------------S?????--------B??????------?S-------------------------------SS??--------?-----??EEEEE???--TTT?SSS-?E--EEEES????HHHHHHHHHTTHHHHHHHSSS?S 1HNS|A PF00817.15_IMS_seed 113 413 !Q:2,2|11,13|18,27|29,31|35,35|42,92|99,99|105,105|108,109|112,112|121,122|124,138|140,142|144,144|146,157|162,163|169,169|174,175|178,178|182,182|184,184|188,190|197,198|210,210|217,220|222,230|236,236|243,250|252,252|263,264|266,266|288,329|331,331|336,340|346,348|353,355|358,360|362,362|365,365|390,396 Q:0,1|3,10|14,17|28,28|32,34|36,41|93,98|100,104|106,107|110,111|113,120|123,123|139,139|143,143|145,145|158,161|164,168|170,173|176,177|179,181|183,183|185,187|191,196|199,209|211,216|221,221|231,235|237,242|251,251|253,262|265,265|267,287|330,330|332,335|341,345|349,352|356,357|361,361|363,364|366,389|397,412 EE?TTHHHHHH---HHHT----------T?-?TTS?EEEEET---------------------------------------------------TEEEEE?HHHHT-TT??TT-SBHHHHHH--H---------------H---S-S-?----------EEEE??EEETT?SSEE??TT?STT?S?GGG???STTEEE??HHHHHHHHHHH-HHHHHH-?--S?--------EEEEE-TTEEEE--------E?HHHHHHHHHH??S?EEETTEEHHHHTHHHHHHHHH??----------------------------------------S?TTSB?????GGGGG???SSEE??-TT???S?SS-HHHHHHHHHHHHHHHHHHHHHHHT-?--???EEEEESSHHHHHHHHH 3BQ0|A PF00819.12_Myotoxins_seed 2 43 !Q:0,0|9,10|12,12|16,17|26,26|30,30|33,33|36,36|39,42 Q:1,8|11,11|13,15|18,25|27,29|31,32|34,35|37,38 ?HHHHHTTB??B?GGG??SSSSTTBB?SSS?TT?BB?BS???- 1Z99|A PF00820.14_Lipoprotein_1_seed 7 270 !Q:0,4|13,13|17,17|19,20|22,29|35,36|40,40|62,62|64,64|70,70|74,74|81,81|85,85|93,93|110,110|116,117|119,119|123,123|131,131|135,135|142,143|146,146|148,148|155,155|158,159|166,166|169,169|190,191|199,202|206,206|233,233|237,237|244,244|248,248|252,252|254,255|258,259|269,269 Q:5,12|14,16|18,18|21,21|30,34|37,39|41,61|63,63|65,69|71,73|75,80|82,84|86,92|94,109|111,115|118,118|120,122|124,130|132,134|136,141|144,145|147,147|149,154|156,157|160,165|167,168|170,189|192,198|203,205|207,232|234,236|238,243|245,247|249,251|253,253|256,257|260,268 ?????GGGEEEEE?GGG?E--E--------EEESS??TTS?EEEEEEETTEEEEEEESSSSS?E-EEEEE?TTS?EEEEEE?TTS?EEEEEEE?TTSSSEEEEEEEETTS?EEEEE--E?TTS?EEEEEEE?TTS?EEEEES??TT-S?EEEEEE?SS-?EEEEEE?SS-EEEEEEEETTEEEEEEEETT??EEEEEEE????TTT?EEEEEEGGGTEEEEEETTEEEEEEEE?TTS?EEEEEB?TTS-SSB?S??EE??SHHHHHHHH? 3CKG|A PF00821.13_PEPCK_seed 56 697 !Q:10,11|17,20|37,37|41,42|52,54|57,57|60,61|69,69|77,79|83,88|91,92|95,95|104,104|129,129|132,132|135,136|143,143|162,166|170,171|174,176|183,183|185,186|189,189|191,194|196,197|201,204|206,206|209,209|219,224|231,232|238,238|255,257|261,262|267,267|274,274|277,278|280,280|288,289|300,303|305,308|311,311|320,320|326,327|331,331|333,337|341,343|350,350|353,354|358,358|366,367|370,370|372,372|377,377|384,385|388,388|391,396|399,410|413,413|417,423|426,426|428,429|431,434|436,436|439,440|442,444|446,446|449,449|458,458|462,463|468,468|471,471|481,483|487,488|493,493|502,502|507,507|511,512|515,515|518,519|521,522|526,526|530,530|534,534|537,537|552,558|561,564|570,570|572,573|575,575|577,577|580,580|584,585|593,593|604,609|611,611|622,622|627,628|632,635|637,645|651,653|662,662|668,668|679,679|696,697 Q:0,9|12,16|21,36|38,40|43,51|55,56|58,59|62,68|70,76|80,82|89,90|93,94|96,103|105,128|130,131|133,134|137,142|144,161|167,169|172,173|177,182|184,184|187,188|190,190|195,195|198,200|205,205|207,208|210,218|225,230|233,237|239,254|258,260|263,266|268,273|275,276|279,279|281,287|290,299|304,304|309,310|312,319|321,325|328,330|332,332|338,340|344,349|351,352|355,357|359,365|368,369|371,371|373,376|378,383|386,387|389,390|397,398|411,412|414,416|424,425|427,427|430,430|435,435|437,438|441,441|445,445|447,448|450,457|459,461|464,467|469,470|472,480|484,486|489,492|494,501|503,506|508,510|513,514|516,517|520,520|523,525|527,529|531,533|535,536|538,551|559,560|565,569|571,571|574,574|576,576|578,579|581,583|586,592|594,603|610,610|612,621|623,626|629,631|636,636|646,650|654,661|663,667|669,678|680,695 HHHHHHHHHH??SEEEE????HHHHHHHHHHHHHTTS?EEE--TTSBSEEEE???TT?SS??GGGEEEE?SSHHHHS???SSS??----SS??EE?HHHHHHHH-HTTSTTTTTTSEEEEEEEEESSTT?TT?EE--EEEEES?HHHHHHHHHHSEESHHHH-----HHH--TT???EEEEEE?S??SS?S----S??STT????G-GG?EEEEETTTT------EEEEES??SHHHH?TIIIIITTHHHHHHHH---HHT-?EEES?EEEEEE?TT--S?EEEEEEE??TTSSHHHHHT????S----TT?EEEEEESS?EEEEE?-TTS?E-----EEE???SEEEEE?TT??TTT?HHHHHHT--TB-S?EEES?EEETTS-?EE?TT??????TT----------??EE?TTS-------SE-E?-T----T?SS-?S---S?TT?EEEEEGGG?TTB?-TTTT?TT?EEEEEEEEE???SSS??SEEE?SSHHHHHH-HHHT?EEE??SS-SS??S??EEE?GGG?TTT?SS?HHHHHHHHHHGGGS-------TT????EEEEE?S??B?T-TS?BSS??GGGGHHH-HHHHHHHHHT----?-S?EEEETTEEEE?TTTS??TTS---?S?----?---HHHHS???HHHHHHHH-HHHHH-HHHHHTGGGS?HHHHHHHHHHHHHHHT?- 2QF2|A PF00823.14_PPE_seed 146 177 !Q:2,4|16,17|51,54|57,57|59,60|70,70|107,108|122,123|128,128|137,143|150,150|153,153 Q:0,1|5,15|18,50|55,56|58,58|61,69|71,106|109,121|124,127|129,136|144,149|151,152|154,176 SS?--HHHHHHHHHHS??THHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTT----TT-S??HHHHHHHHH-THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS??HHHHHHHHHHHHH--HHHT?TTSTTHHH-------HHHHHH-HH-HHHHHHHHHHHHHHHHHHHHHHH 2G38|B PF00825.13_Ribonuclease_P_seed 141 209 !Q:0,4|8,9|19,19|25,25|28,31|35,36|40,47|51,80|85,111|114,115|118,120|124,124|126,126|148,148|150,150|152,157|166,167|176,177|180,180|187,195|200,202|207,208 Q:5,7|10,18|20,24|26,27|32,34|37,39|48,50|81,84|112,113|116,117|121,123|125,125|127,147|149,149|151,151|158,165|168,175|178,179|181,186|196,199|203,206 ?-?-?SSB??HHHHHHHHH-HHSEE-EE?---SSE--EEE--------EEE------------------------?-----SSSS?--------------------------EE--EE???GGG?S-HHHHHHHHHHHHHHHHHHTTT-S?S------SEEEEEEE?-TTHHHHGG--GS?HHHHHH---------HHHH---HHTT?? 3Q1R|A PF00827.12_Ribosomal_L15e_seed 57 216 !Q:0,1|29,43|47,47|55,55|57,57|66,68|82,82|85,89|92,92|99,100|104,104|106,109|112,112|125,125|129,129|140,140|152,152|161,161|180,180|190,215 Q:2,28|44,46|48,54|56,56|58,65|69,81|83,84|90,91|93,98|101,103|105,105|110,111|113,124|126,128|130,139|141,151|153,160|162,179|181,189 ??HHHHHHHHHTTTSHHHHHHHHHHHHHH---------------HHS?SEEEESS?S?HHHHHHHT??-SSTTEEEEEEEEE?SS?????SS?SSTTSS??SSS?S???-SS?HHHHHHHHHHHH-STT?EEEEEEEEEE?SSEEEEEEEEE?TTSTTTSS?TTTGGGGSGGGTTHHHHT?SHHHHHHHT?--???-??????????????---?? 1S1I|L PF00828.14_Ribosomal_L18e_seed 104 187 !Q:0,0|4,6|8,10|13,13|17,17|21,23|37,39|41,43|46,56|59,63|68,70|73,99|104,104|109,109|117,120|124,125|127,130|136,141|145,146|150,155|157,157|159,161|169,169|181,181|186,186 Q:1,3|7,7|11,12|14,16|18,20|24,36|40,40|44,45|57,58|64,67|71,72|100,103|105,108|110,116|121,123|126,126|131,135|142,144|147,149|156,156|158,158|162,168|170,180|182,185 ?TTT???S?--TT?SSS-TTT---TTTSHHHHTTTSS---S?--SS?-?----????TT?---?TTSS???EE---------------------------ETTT?TTSS?HHHHTTS----SSS??S-???EEEST------TTT??EEE??????S-S?-?EEEESEE?HHHHHHHHHTT?EEEE? 2ZJQ|I PF00829.16_Ribosomal_L21p_seed 67 102 !Q:0,1|14,14|22,25|27,29|32,32|37,40|42,43|46,47|49,52|56,56|59,61|68,72|74,76|81,82|89,90|95,96|98,98 Q:2,13|15,21|26,26|30,31|33,36|41,41|44,45|48,48|53,55|57,58|62,67|73,73|77,80|83,88|91,94|97,97|99,101 ??EEEEETTEEEEE?SSEEEEE???-S?-?TT?EEEE????B??SS--S????SSS?SS--?EEEEEE???-?B???EEEE??BTTTTB??EEEE??B?EEE 2ZJQ|O PF00830.14_Ribosomal_L28_seed 114 86 !Q:0,3|7,10|12,14|16,31|33,34|36,45|47,48|50,53|60,60|64,64|72,72|79,80|85,85 Q:4,6|11,11|15,15|32,32|35,35|46,46|49,49|54,59|61,63|65,71|73,78|81,84 ??-?SSS????B?-?B???-------------T--T??------??B??B????EEEEEE?SSS?SEEEEEE?TTHHHH--HHHH? 2ZJQ|U PF00831.18_Ribosomal_L29_seed 156 62 !Q:7,7|9,9|27,28|33,38|40,40 Q:0,6|8,8|10,26|29,32|39,39|41,61 HHHHHHS?H-HHHHHHHHHHHHHHHHH??SSSS-???--S?HHHHHHHHHHHHHHHHHHHHH 2ZJQ|V PF00832.15_Ribosomal_L39_seed 44 43 !Q:13,15|25,27|29,29|32,34|38,42 Q:0,12|16,24|28,28|30,31|35,37 HHHHHHHHHHHTS???HHHHHHHTS???S?TT???TTT????? 1FFK|Y PF00833.13_Ribosomal_S17e_seed 32 140 !Q:0,5|23,25|27,27|38,39|43,43|54,56|70,71|73,76|78,80|93,95|97,97|99,102|104,109|111,112|114,114|124,124|127,133|135,139 Q:6,22|26,26|28,37|40,42|44,53|57,69|72,72|77,77|81,92|96,96|98,98|103,103|110,110|113,113|115,123|125,126|134,134 ??????HHHHHHHHHHHHHHTTT??-S?HHHHHHHHHH--HEE?SSHHHHHHHH---HHHHHHHHHHTTS??T----T???HHHHHHHHHHTT???S?S????S------S??B?STHHHHHHT-TT??-????B????? 2XZM|V PF00834.14_Ribul_P_3_epim_seed 13 214 !Q:9,9|25,25|40,40|42,42|44,44|55,56|59,61|83,83|85,85|91,91|96,96|111,111|118,118|121,122|133,133|142,151|162,164|173,179|187,188|200,201 Q:0,8|10,24|26,39|41,41|43,43|45,54|57,58|62,82|84,84|86,90|92,95|97,110|112,117|119,120|123,132|134,141|152,161|165,172|180,186|189,199|202,213 EEEEBGGGS?GGGHHHHHHHHHHTT?SEEEEEEEBSSSSS?B?B?HHHHHHHGGG??SE---EEEEEESSSGGGTHHHHHHHT?S-EEEEE?STTT?TTHHHHHHHHHHTT?EEEEEE?TT??GGGGTTTGGG?SEEEEESS??????????GGGHHHHHHH---HHHHHHHT----???EEEEESS??TTTTHHHHHHT??EEEESHHHHTSS 1H1Y|A PF00836.14_Stathmin_seed 4 140 !Q:0,4|18,20|22,43|45,45|136,139 Q:5,17|21,21|44,44|46,135 ?????EEEEEETTEEEEE???S??????????????????????S?TTSSTTTHHHHHHHHHTTSSTTTTTTTTTHHHHHHHHHHHHHHHHTTTTHHHHTTSHHHHHHHHHHHHHHHTTTHHHHTTTTTTTTTGGG???? 3RYF|E PF00838.12_TCTP_seed 9 183 !Q:0,0|16,18|20,20|32,33|39,40|43,45|50,52|55,60|63,63|80,80|84,84|88,88|112,112|133,133|145,145|153,153|155,156 Q:1,15|19,19|21,31|34,38|41,42|46,49|53,54|61,62|64,79|81,83|85,87|89,111|113,132|134,144|146,152|154,154|157,182 ?EEEEESSSTTTSEEE???E-EEETTTEEEEE??EEEEE--TT???TTSS???SS????--SS?SSSSEEEEEHHHHHHT?EEE?TTT?HHHHHHHHHHHHHHHHHHHHHHT?SSSHHHHHHHHHHHHHHHHT?HHHHTTEEEEE?TTTTTTT?S??EEEEEEEEETTEEEEEEEEEGGGEEE 2LOY|A PF00840.15_Glyco_hydro_7_seed 18 454 !Q:2,3|6,10|23,24|35,35|40,40|48,51|60,60|64,64|77,80|82,83|88,88|92,92|105,110|113,113|125,125|127,127|130,131|142,142|145,146|157,159|167,167|170,171|178,181|185,186|188,189|198,198|201,201|204,210|213,213|219,220|228,228|231,231|238,238|242,242|244,245|254,254|260,261|269,269|272,274|276,276|282,282|290,291|299,299|316,316|333,337|341,344|348,348|361,363|381,381|391,391|408,408|416,416|419,420|425,425|433,433|436,436|450,451|453,453 Q:0,1|4,5|11,22|25,34|36,39|41,47|52,59|61,63|65,76|81,81|84,87|89,91|93,104|111,112|114,124|126,126|128,129|132,141|143,144|147,156|160,166|168,169|172,177|182,184|187,187|190,197|199,200|202,203|211,212|214,218|221,227|229,230|232,237|239,241|243,243|246,253|255,259|262,268|270,271|275,275|277,281|283,289|292,298|300,315|317,332|338,340|345,347|349,360|364,380|382,390|392,407|409,415|417,418|421,424|426,432|434,435|437,449|452,452 EE??SS?????EEEEEEEEETTE--EEEEEEEEEE?GGGS?EEESSSS?---BSEETTEE?TTT?SSHHHHHHHEEE????H--HHHH?EEE?SSEEEEESEETT------EE?EEEEEEEETTE-E?EE??TTEEEEEEEE?TT??TTEEEEEEEE???TTTTTTT?TT??SGGGGT????BTT??S??SEETTEES?TT?EE???????EE?SEEEE??EEEEEEE?SS?EEEEEE?BSS?S-?EEEEGGGG?TTTSS--STTSSSB?SS???B?TTTTT?TTSEETT--SSEETTS?EEEEEEEEETTSSTTS?EEEEEEEEEETTEEEE?????STT???-SSB?HHHHHHHHHHHT???HHHHTTHHHHHHHHHHH?EEEEEEEEE?TTTTTHHHHSBSSSSS?TTSTTSB?SS??TTTT?HHHHHHH?TT?EEEEEEEEEEETT-?S? 2V3R|A PF00842.16_Ala_racemase_C_seed 121 188 !Q:0,0|3,3|8,8|15,16|19,19|21,22|28,28|31,32|36,36|43,44|49,53|58,59|61,76|79,82|90,91|95,98|100,102|105,105|110,110|112,126|128,130|133,141|148,148|152,153|158,158|169,169|178,178|180,180|183,183 Q:1,2|4,7|9,14|17,18|20,20|23,27|29,30|33,35|37,42|45,48|54,57|60,60|77,78|83,89|92,94|99,99|103,104|106,109|111,111|127,127|131,132|142,147|149,151|154,157|159,168|170,177|179,179|181,182|184,187 ?EE-EEEE?SEEEEE-?TT?E--ESGGG?EE??SSE-EEEEES??GGGT--??-GGGG--G?---------------EE----EETTEEE--EEE----S???SS?EEEE?S---------------S???TT--------?EEEEEE-EET--TEEE?HHHHHHHHTS?TTHHHHHS?T-TS?EEEE 1BD0|A PF00843.12_Arena_nucleocap_seed 17 560 !Q:0,5|20,23|38,39|52,52|74,74|76,76|78,82|86,86|91,91|115,115|120,120|123,123|126,127|143,156|159,159|163,163|165,170|173,173|178,178|180,182|193,194|199,199|209,209|219,221|232,232|242,243|247,248|252,252|269,271|275,276|278,278|298,301|304,304|307,308|320,320|324,324|330,330|333,334|336,336|344,375|390,390|394,394|402,402|406,406|413,413|417,417|424,426|428,428|441,441|443,443|451,451|453,453|464,464|467,467|473,473|486,487|494,497|516,518|520,520|522,522|526,532|536,544 Q:6,19|24,37|40,51|53,73|75,75|77,77|83,85|87,90|92,114|116,119|121,122|124,125|128,142|157,158|160,162|164,164|171,172|174,177|179,179|183,192|195,198|200,208|210,218|222,231|233,241|244,246|249,251|253,268|272,274|277,277|279,297|302,303|305,306|309,319|321,323|325,329|331,332|335,335|337,343|376,389|391,393|395,401|403,405|407,412|414,416|418,423|427,427|429,440|442,442|444,450|452,452|454,463|465,466|468,472|474,485|488,493|498,515|519,519|521,521|523,525|533,535|545,559 ??????HHHHHHHHHHSGGG????HHHHHHHHHHHHHH??HHHHHHHHHHHH?SSEEHHHHHHHHHHHHHHHHH?S?B?????EEE?BTTB?HHHHHHHHHHHHHHHHHHHHHHT-HHHH?EE?SS??HHHHHHHHHHHTTTT??????????????EE?SEE?S-----?TT-TTTT?S???HHHHHHHHHH--HTTS?HHHHHHHHH-HHHHHHHHS???HHHHHHHTTT?TTTTSSBSS??STT??TTS?BHHHHHHHHHTTSSSS??-GGG??B?TTTHHHHHHHHHHHHHHHT????SS?SS??HHHHHHHHHHH?SSB?TTTSB?TT??S?HHHHEEE??????-????????????????????-????HHHHHHHHHHGGGS?TTS?EEEEEES?TTS?SEEEEE?TTT?EEEEEE???S?HHHHHHHHHHTT?B?GGGSTTB?T-THHHHHHHHS?SS?EEEES?HHHHHHHHHTTT??SSEEEE????HHHHTTTHHHHHHHHGGG???B?S?EEE???????EEE?-----???HHHHHHHHHHHHHTS 4GV9|A PF00847.15_AP2_seed 206 78 !Q:0,2|6,7|10,10|12,12|15,18|21,22|28,28|30,34|37,43|45,45|57,57|60,61|76,76 Q:3,5|8,9|11,11|13,14|19,20|23,27|29,29|35,36|44,44|46,56|58,59|62,75|77,77 ???TTE--EE?T-TS?---EE--EEEEE-T-----TT-------T-SEEEEEEEESS-HH--HHHHHHHHHHHHTT?S 3GCC|A PF00848.14_Ring_hydroxyl_A_seed 128 387 !Q:2,2|5,5|20,20|23,23|27,27|29,30|36,36|38,38|44,46|52,53|56,57|72,72|75,103|107,112|118,118|123,123|131,131|165,166|174,193|205,207|213,215|222,225|229,229|242,253|255,255|259,272|288,288|290,294|310,313|323,332|335,336|341,342|345,346|350,350|355,355|359,360|362,362|365,366|369,372|383,385 Q:0,1|3,4|6,19|21,22|24,26|28,28|31,35|37,37|39,43|47,51|54,55|58,71|73,74|104,106|113,117|119,122|124,130|132,164|167,173|194,204|208,212|216,221|226,228|230,241|254,254|256,258|273,287|289,289|295,309|314,322|333,334|337,340|343,344|347,349|351,354|356,358|361,361|363,364|367,368|373,382|386,386 HH-HH-HGGGHHHHHHHHSS?TT?EEE?S??EEEEE?S?HHHHH---HHHHH??TT--TTTTTTHHHHHHHS?TT??---------------------------TTT??????EEEEE?SSSS?EEEEEES?HHHHHHHHHHHHHHHHHSHHHHHHHHHHTGGGT??GGGEEEE--------------------EEEETTTEEEE---TTTTE---EEEEEE---?STT?EEEEEEEEEETT------------S?HHH--------------HHHHHHHHHHHHSTT?T-----THHHHHHHHHHHHHH----TTSSGGGTS---------?EE??TTTT??BS??SSS?SEEE-ESS??H-HH--HH----HHHHHHHHHH???H 3GZX|A PF00849.17_PseudoU_synth_2_seed 57 334 !Q:2,2|8,8|11,12|15,15|23,45|55,55|59,60|69,69|71,73|76,76|97,100|104,105|115,158|161,165|170,171|175,239|242,242|245,245|249,249|254,255|265,306|319,320|326,328 Q:0,1|3,7|9,10|13,14|16,22|46,54|56,58|61,68|70,70|74,75|77,96|101,103|106,114|159,160|166,169|172,174|240,241|243,244|246,248|250,253|256,264|307,318|321,325|329,333 SE-EEEEE?SS??SS?BTTBSSS-----------------------SHHHHHHHH?GGG--GGSGGGGB?S???TT?EEEEEEESSHHHHHHHHHHH----HTT?-SEEEEEEEE--------------------------------------------ES?????EEEE??EEE----------------------------------------------------------------?SS?TT?EEE?TTSB??EEEEEEEEE?-----------------------------------------SSEEEEEEEESS??TTHHH---HHHHH 1KSL|A PF00850.14_Hist_deacetyl_seed 148 1151 !Q:0,31|33,33|35,35|37,41|47,50|58,63|65,65|67,75|83,148|150,156|161,161|163,166|170,230|234,235|239,292|295,358|361,361|365,365|372,372|374,375|384,388|401,401|405,409|412,469|471,473|477,481|484,491|494,495|498,544|546,657|659,672|674,678|684,684|694,713|716,717|720,722|724,727|733,733|737,738|747,793|795,828|839,841|844,848|854,861|863,863|865,934|940,943|948,948|951,951|953,960|962,967|971,973|982,992|995,995|999,999|1002,1004|1008,1038|1040,1044|1052,1054|1059,1060|1062,1071|1074,1078|1080,1097|1105,1107|1116,1119|1122,1122|1124,1124|1129,1133|1135,1135 Q:32,32|34,34|36,36|42,46|51,57|64,64|66,66|76,82|149,149|157,160|162,162|167,169|231,233|236,238|293,294|359,360|362,364|366,371|373,373|376,383|389,400|402,404|410,411|470,470|474,476|482,483|492,493|496,497|545,545|658,658|673,673|679,683|685,693|714,715|718,719|723,723|728,732|734,736|739,746|794,794|829,838|842,843|849,853|862,862|864,864|935,939|944,947|949,950|952,952|961,961|968,970|974,981|993,994|996,998|1000,1001|1005,1007|1039,1039|1045,1051|1055,1058|1061,1061|1072,1073|1079,1079|1098,1104|1108,1115|1120,1121|1123,1123|1125,1128|1134,1134|1136,1150 ?-----------?????----??-----??-?S-S?T-----HHHHH----HHHHHHH------H-T---------TTTTSEE------------------------------------------------------------------E??????-HHHH-T----TTS------------------------------------------------------------?HHH--HHH------------------------------------------------------HH?????--???------------------------??--------------??????????--??EE?TTS?EESSSS?B??TTTHHHHH-----HHHHHHHHHHHH-HHH-----HT----------------------------------------------------------S?--SEE-----EE??------SS??TT?-?--------------------------------------------S----------------------------------------------------------------------------------------------------------------S?------------?B-----TTBSS?HHHHHHHHH--------------------HH--SS?-?S---?EEEEE?SSS??HHHHHHHT-----------------------------------------------T----------------?-----------------TTEEEEEEEE?--GG-----GTSTT---?-???T-T??-?-------------------------------------------------------------?----GGGTT---?EEEE-EE?S--------T------TSS???HHHHHHHH-----------HH-THH-HH---HHH-------------------------------H-??--SEEEEEE???SBTT??T----------TT???-?B?-----------------HHHHHHH---HHHHHTST----TS?E-EEEE?????H-HHHHHHHHHHHHHHH 3F06|A PF00851.13_Peptidase_C6_seed 19 456 !Q:0,337|340,340|354,354|374,374|377,377|399,399|401,402|417,418|422,422|429,432|446,447|455,455 Q:338,339|341,353|355,373|375,376|378,398|400,400|403,416|419,421|423,428|433,445|448,454 ---------------------------?-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------???????????????????????????????????????TT?TTHHHHHHHGGGS?GGGHHHHHHHHHHTHHHHH?SS?BHHHHHHHHHHHHHHSGGGGG?B??EEEEETTTTEEEEE??SSS?SSSTTB????BHHHHHHHHHSSS??GGGGSEE? 3RNV|A PF00852.14_Glyco_transf_10_seed 49 523 !Q:1,2|5,6|31,62|64,65|69,70|72,72|77,79|85,94|100,100|106,108|112,118|122,122|126,130|135,136|138,138|142,144|148,149|152,169|181,181|185,185|188,190|196,198|202,203|206,208|213,213|219,239|246,246|248,276|280,286|288,289|294,295|297,303|305,305|307,309|321,321|323,324|327,327|331,337|339,340|342,342|345,346|348,348|351,355|368,368|371,373|376,378|383,383|390,390|397,399|406,407|409,409|411,411|434,443|446,446|453,457|462,485|488,501|508,512|516,521 Q:0,0|3,4|7,30|63,63|66,68|71,71|73,76|80,84|95,99|101,105|109,111|119,121|123,125|131,134|137,137|139,141|145,147|150,151|170,180|182,184|186,187|191,195|199,201|204,205|209,212|214,218|240,245|247,247|277,279|287,287|290,293|296,296|304,304|306,306|310,320|322,322|325,326|328,330|338,338|341,341|343,344|347,347|349,350|356,367|369,370|374,375|379,382|384,389|391,396|400,405|408,408|410,410|412,433|444,445|447,452|458,461|486,487|502,507|513,515|522,522 E??TT??HHHHHHHHTSHHHHHHHTTSEEEE--------------------------------E??TTB??S-EEEE???THHHH----------HHHHH?SEEEE-??SSS?---???TTT?SEE-----EESS??B?GGG---EEE??HH------------------HHHHHHHHHHT?BTT?SS???TTSGG---GSS??BS?--HHHH?HHHHH---------------------HHTTSS?T-----------------------------TSS-------E--EEEE??S?---???H-H---HHHHHHHHTTT-S??EE?SST-------T??S-SS??S?HH-----HHHTTEEEEEEE?SS-??TT???THHH-HHHHTT?EEEEES--?TTGGGT--S?G-GGSEEGGGSSSHHHHHHHHHHH----------HT?HHHHHH-----HHHS-----------------------?SS-------------?EETTEE?---?GGG?----?H 2NZW|A PF00853.14_Runt_seed 6 135 !Q:0,11|17,17|26,28|35,37|40,41|48,50|53,53|61,61|64,64|68,68|72,72|83,83|86,86|89,89|91,93|96,97|105,105|109,109|124,134 Q:12,16|18,25|29,34|38,39|42,47|51,52|54,60|62,63|65,67|69,71|73,82|84,85|87,88|90,90|94,95|98,104|106,108|110,123 --??????????EEEEE?SSTTEEEE???SEEETT???SS??EEEESS???TT?EEEEEEE?SS?TTB?EES?EEEBSSSEEE?SS?EE?S???TT??EEEEEEE?SSS?EEEEEEEEEEEESS??????????? 1HJB|C PF00854.16_PTR2_seed 25 520 !Q:17,19|24,25|27,61|91,92|95,99|129,136|140,140|172,173|176,178|200,203|212,218|221,236|249,255|267,267|270,276|295,295|317,318|320,322|326,326|329,330|359,365|368,369|390,439|443,448|455,455|457,457|459,463|468,468|488,492|496,496|500,500 Q:0,16|20,23|26,26|62,90|93,94|100,128|137,139|141,171|174,175|179,199|204,211|219,220|237,248|256,266|268,269|277,294|296,316|319,319|323,325|327,328|331,358|366,367|370,389|440,442|449,454|456,456|458,458|464,467|469,487|493,495|497,499|501,519 HHHHHHHHHHHHHHHHH---HHSS??H-----------------------------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHS?-TT----?TTHHHHHHHHHHHHHHHHHHHHHHHHHHH--------HHT?HHHHHHHHHHHHHHHHHHHHHHHHHHHTTTT??SS???HHHHHHHHHHHHHHHHHHHHH----HHHHHHHT----???HH----------------HHHHHHHHHHHH-------HHHHHHHHHHH?TT?-----?HHHHHHHHHHHHHHHHHH-HHHHHHHTTTTHHHHHHHHTB??E---ETT-EE??GGGGGGHHHHHHHHHHHHHHHHHHHHGG-------GS??HHHHHHHHHHHHHHHHHHHH--------------------------------------------------HHH------HHSSSS?B?T-----HHHH-HHHHHHHHHHHHHGGGHHH-----HHH-HHS?GGGGGGHHHHHHHHHHHHH 4APS|A PF00855.12_PWWP_seed 273 320 !Q:0,1|4,5|10,19|23,29|35,118|121,121|123,151|153,156|162,164|166,174|176,177|179,183|186,190|192,192|195,195|201,206|209,210|212,226|229,240|242,245|247,280|283,300|304,306|315,317|319,319 Q:2,3|6,9|20,22|30,34|119,120|122,122|152,152|157,161|165,165|175,175|178,178|184,185|191,191|193,194|196,200|207,208|211,211|227,228|241,241|246,246|281,282|301,303|307,314|318,318 ??TT-?EEEE----?-?---TTS---?--?EEEEE???---------------------------------------??-----??------?---?-----------??---------TT?E-----------------------------E----EEETT---T?-?------E--E-----EE--?--G-GG-EEEHH------HH--H---------------HH------------H---?S-----------------?------------?---SS------------------TTH---HHHHHHHH---H? 3QJ6|A PF00856.23_SET_seed 267 523 !Q:8,8|10,10|13,15|19,22|24,25|29,30|44,277|282,396|400,400|408,408|412,413|418,418|421,436|438,441|443,458|468,497|510,510|512,512|515,515|520,522 Q:0,7|9,9|11,12|16,18|23,23|26,28|31,43|278,281|397,399|401,407|409,411|414,417|419,420|437,437|442,442|459,467|498,509|511,511|513,514|516,519 SEEEEESS?B?TT?--EEE----E??SEE--EEGGGHHHHHHHH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHHT??---------------------------------------------------------------------------------------------------------------??EEE?SSSEEEE?TTT??GGGG?EE---------------?S----S?---------------SEEEEEEEE------------------------------TTEEEEEEEESS?B?TT?EEEE??? 3F9X|A PF00857.15_Isochorismatase_seed 64 271 !Q:4,5|8,11|13,13|21,22|49,50|55,65|70,72|74,86|89,89|93,93|96,97|108,108|119,119|123,125|127,130|132,132|135,147|153,159|171,173|176,182|190,190|196,198|209,209|211,216|225,229|232,232|234,240|244,244|254,258|262,262|267,267 Q:0,3|6,7|12,12|14,20|23,48|51,54|66,69|73,73|87,88|90,92|94,95|98,107|109,118|120,122|126,126|131,131|133,134|148,152|160,170|174,175|183,189|191,195|199,208|210,210|217,224|230,231|233,233|241,243|245,253|259,261|263,266|268,270 EEEE--EE--??B-HHHHSTT-?TTHHHHHHHHHHHTHHHHHHHHHHHH--HHHT-----??----EEEE???B?------------TT?TTS?SS??THHHHHHHHT?SBTTSTTTSB?GGG???T----T?EE??--???------SSSHH-------HHSSHHHHHHH---HT?--?---EEEEEEE?TTTHH---HHHHHHHHHT-T?-----EEEEEEEE-----EE?S?------HHH-HHHHHHHTH-----HHH-SEEE?HHH 3R2J|A PF00858.19_ASC_seed 114 1311 !Q:0,79|104,104|106,107|116,117|119,120|124,126|134,135|137,143|148,151|161,161|167,167|172,173|176,200|211,299|301,310|313,455|464,471|473,474|476,476|481,484|493,501|503,505|509,514|518,700|702,708|710,710|712,712|716,716|722,783|786,789|792,796|810,819|824,827|829,830|833,910|912,915|923,923|927,929|934,941|945,945|949,950|952,952|964,986|991,992|995,995|998,1017|1024,1026|1045,1045|1047,1047|1050,1082|1086,1086|1088,1099|1101,1102|1105,1107|1112,1121|1131,1147|1150,1150|1155,1160|1170,1172|1182,1182|1190,1208|1214,1215|1231,1233|1239,1239|1249,1249|1255,1285|1304,1310 Q:80,103|105,105|108,115|118,118|121,123|127,133|136,136|144,147|152,160|162,166|168,171|174,175|201,210|300,300|311,312|456,463|472,472|475,475|477,480|485,492|502,502|506,508|515,517|701,701|709,709|711,711|713,715|717,721|784,785|790,791|797,809|820,823|828,828|831,832|911,911|916,922|924,926|930,933|942,944|946,948|951,951|953,963|987,990|993,994|996,997|1018,1023|1027,1044|1046,1046|1048,1049|1083,1085|1087,1087|1100,1100|1103,1104|1108,1111|1122,1130|1148,1149|1151,1154|1161,1169|1173,1181|1183,1189|1209,1213|1216,1230|1234,1238|1240,1248|1250,1254|1286,1303 ?????????????--?-????---------????----------------------?---------------------??TTTTTSSHHHHHHHHHHHHHHHHH-T??EEEEEEEE??S--SEE-??EEEEEES??S-------BTTT--??HHHHHHHTT-TTTSS?SSSS??SS???---------------------?TTHHHHHHHT-----------------------------------------------------------------------------------------T??--------TT?------------------------------------------------------------------------------------------------------------???----------------------------???HHHHHHHH--------S??H-HHHE----EEEEETTE---------E?-?GGG------EEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-------E?S-SSE-EEEET???-----------------------------------------------------------SS????EE----?SSSGGGSEEEEEE?------?--GGGB????S??TT?----------------------------------------------------------------------------?S--??SEEEEEE?TTS???HHHH-------?EEE?TTE--E-EEEEEEEEEEE-------???-------------TTTS?-EE?SS------------------??BTTBSS?-?HHHHHHHHHHHHHHHHHS?B?TT?-------------------------------?SSS?B----------??H--HH---HHHT----------HHHHHHHHH-----------------HT?SSSS--?-??EESEEEEEE---EEEEEEESS?TTTHHHH-------------------HHHTT??HHHHHHHEEEEEEEE---EEEEE-EEEEEEESS?HHHHH-------------------------------HHHHHHHHHHSSSSTTTS??????? 3S3W|A PF00860.15_Xan_ur_permease_seed 20 446 !Q:27,41|59,62|67,71|75,75|82,85|93,105|131,131|134,134|140,141|168,171|175,177|179,181|202,204|230,231|238,252|257,257|260,279|311,311|315,317|340,343|347,347|360,361|377,378|389,389|393,393|419,419|439,443|446,446 Q:0,26|42,58|63,66|72,74|76,81|86,92|106,130|132,133|135,139|142,167|172,174|178,178|182,201|205,229|232,237|253,256|258,259|280,310|312,314|318,339|344,346|348,359|362,376|379,388|390,392|394,418|420,438|444,445 HHHHHHHHHHHHHHHHHHHHHHHTTTS?--------------HHHHHHHHHHHHHHHHH----HTTT?????EEE?GGGHHH----HHHHGGG?------------HHHHHHHHHHHHHHHHHHHHHHHTT?SH-HHHHH??HHHHHHHHHHHHHHHHHHHHHHHTSS?---BTT---B???HHHHHHHHHHHHHHHHHHHS---SSTTTTTHHHHHHHHHHHHHHHHHH--HTTSSH---------------HHHS?SS???---??????------??HHHHHHHTHHHHHHHHHHHHHHHHHHHHHTS?TII---IIIHHHHHHHHHHHHHHHHHHT?-??EEE?HHHHHHHHHHTB??HHHHHHHHHHHHHHT??HHHHHHHTTS?HHH-HHHHHHHHHHHHHHHHHHHHHHTTS?TTSHHHHHHHHHHHHHHHH?????SS- 3QE7|A PF00861.17_Ribosomal_L18p_seed 33 149 !Q:1,3|12,14|20,23|30,30|33,33|41,42|45,46|60,60|63,64|66,66|94,97|100,100|102,110|114,117|119,119|123,123|126,129|132,132|146,146|148,148 Q:0,0|4,11|15,19|24,29|31,32|34,40|43,44|47,59|61,62|65,65|67,93|98,99|101,101|111,113|118,118|120,122|124,125|130,131|133,145|147,147 T???HHHHHHHH???GGGTT????EEEEEE?SS?EEEEEEE??TT??EEEEEEEGGGGGG-GT??S?TTSHHHHHHHHHHHHHHHHHHTSTTSS????SS?S?????????SSS????B?EEE?TT????TT?THHHHHHHHHHTT?B? 2ZJQ|L PF00862.14_Sucrose_synth_seed 4 551 !Q:0,18|33,33|49,49|52,52|56,60|76,76|102,102|107,107|123,125|129,129|133,133|141,145|167,167|181,181|191,191|194,195|215,215|218,218|233,233|235,235|237,237|257,258|270,273|279,280|283,285|289,289|295,295|322,326|334,335|338,338|350,350|353,353|362,362|371,371|373,375|379,379|398,398|401,402|425,426|431,431|433,434|454,454|476,476|482,483|487,488|508,509|512,512|518,523|528,529|532,532|536,537|550,550 Q:19,32|34,48|50,51|53,55|61,75|77,101|103,106|108,122|126,128|130,132|134,140|146,166|168,180|182,190|192,193|196,214|216,217|219,232|234,234|236,236|238,256|259,269|274,278|281,282|286,288|290,294|296,321|327,333|336,337|339,349|351,352|354,361|363,370|372,372|376,378|380,397|399,400|403,424|427,430|432,432|435,453|455,475|477,481|484,486|489,507|510,511|513,517|524,527|530,531|533,535|538,549 ???????????????????TTHHHHHHHHHHHT?SEEEEHHHHHHTTTT-TS?GGG???--STHHHHHHTEEEEEE?SSEEEEEEEEETTEEEEEEEETTSS?EEEE?HHHHHHHHHHHHHSS???TTS?EEE?GGGGTTS?????GGGTTBHHHHHHHHHHHHTTT?HHHHHHHHHHHHH?EETTEEBSB?TT??SHHHHHHHHHHHHHHHHHS?TT?BHHHHHHHHHHTTB?B?S?SBHHHHHHHHHHHHHHHHS??HHHHHHHHHHS????EEEEE??SS???SSS?TTSTT?SHHHHHHHHHHHHHHHHHHHHHHHTT?????EEEEEEE??TT?TTSSTTSSEEE?TT?SSEEEEEE?EEETTEEE?S???TTT?GGGHHHHHHHHHHHHHHH?SS??SEEEEEHHHHHHHHHHHHHHHT??EEEE?S??HHHHSTTTTTTHHHHHHHH?HHHHHHHHHHHHHHSSEEEES?HHHHH??SSS??TTGGGSSEEETTTEEEEES??TT?TTEEE??????TTTS??TT?TTT??GGGHHHHHHHHH? 3S28|A PF00863.14_Peptidase_C4_seed 39 261 !Q:0,12|18,24|52,52|56,58|61,62|66,69|80,81|85,85|89,89|94,94|99,99|104,105|109,112|114,116|118,121|124,125|134,134|143,145|147,148|151,152|162,162|164,166|169,169|172,172|180,181|188,192|202,204|209,210|216,216|220,220|224,226|228,228|230,234|248,260 Q:13,17|25,51|53,55|59,60|63,65|70,79|82,84|86,88|90,93|95,98|100,103|106,108|113,113|117,117|122,123|126,133|135,142|146,146|149,150|153,161|163,163|167,168|170,171|173,179|182,187|193,201|205,208|211,215|217,219|221,223|227,227|229,229|235,247 ?-???????????HHHHT-------TEEEEEEEETTEEEEEEEEEETTEEEE?GGG---GS??SEE----EEEEETTEEE--EES?GGG?EEEE?TTSS?EEEE??TTS????S???B????TT??EEEEEEEE?SSEEEEEE???B??EE--ETTTTEEEE?S???TT?TT?EEEETTT??EEEEEE-----EEETTSSSE---EEEE??TTHHH-HHH?GGG???B?S?????SEEEETTEEEESS????????????? 1LVB|A PF00864.14_P2X_receptor_seed 19 478 !Q:0,20|39,39|43,44|47,47|49,49|58,59|66,72|80,80|86,86|89,90|93,93|112,122|124,130|132,135|139,139|145,147|166,169|173,174|176,176|187,196|199,202|210,210|231,231|234,235|242,245|248,249|251,251|254,255|268,269|277,277|289,289|293,293|297,298|301,302|308,308|310,312|315,317|319,319|322,323|325,325|330,361|367,367|371,371|393,394|396,396|421,477 Q:21,38|40,42|45,46|48,48|50,57|60,65|73,79|81,85|87,88|91,92|94,111|123,123|131,131|136,138|140,144|148,165|170,172|175,175|177,186|197,198|203,209|211,230|232,233|236,241|246,247|250,250|252,253|256,267|270,276|278,288|290,292|294,296|299,300|303,307|309,309|313,314|318,318|320,321|324,324|326,329|362,366|368,370|372,392|395,395|397,420 -----------??????????TTHHHHHHHHTTTTTTTS?TTB??EE?E-EEEEEEEE??EEEEET-------TTEEEEE?TTTTS?SS??SS?EEEEEEEEEEEEEEEEEE-----------E?---???T----TTB?SSTTT-??TTTTTTTTTSEEEEEEEE----SSS--S?EEEEEEEEES--????????SS---?TTGGGGG?EEEEEEEEEETTTTEEEESS?SS??TTTTTT????SS--S?TT??EEEHHHHHHHTT??HHHHHHH?EEEEEEEEEEE?TTS?GGG??EE--EEEEE?S???SS---S?SS?-S?EEEE--------------------------------EEEEE?TTS?EEEEEEEEEEEEEEEEEEEEE??B?HHHHHHHHHHHHHHHHHHHHHHHH??????------------------??????????????-----------------?? 4DW1|A PF00866.13_Ring_hydroxyl_B_seed 44 169 !Q:8,12|14,14|21,21|33,33|35,38|45,50|53,54|58,58|64,64|79,80|86,87|101,102|123,125|142,142|148,150|162,162|166,166 Q:0,7|13,13|15,20|22,32|34,34|39,44|51,52|55,57|59,63|65,78|81,85|88,100|103,122|126,141|143,147|151,161|163,165|167,168 HHHHHHHT-----T?HHHHHT-TEEEEEEEEEE?B????GGGGGG------SB??TTS?EEEEE?HHHHHHHHHHHTTT??GGGSS??EEEEEEEEEEEEE?-SSTTEEEEEEEEEEEEEETT---TEEEEEEEEEEEEEEE?SSTTS---EEEEEEEEEES?SSB?SS 3GZX|B PF00867.13_XPG_I_seed 207 147 !Q:3,3|5,8|10,10|12,13|15,15|25,28|33,39|41,41|44,44|53,56|58,58|60,62|67,67|70,70|72,75|78,88|91,92|94,95|97,97|103,105|112,115|118,122|124,124|127,130|139,145|147,147 Q:0,2|4,4|9,9|11,11|14,14|16,24|29,32|40,40|42,43|45,52|57,57|59,59|63,66|68,69|71,71|76,77|89,90|93,93|96,96|98,102|106,111|116,117|123,123|125,126|131,138|146,146 HHH-T????B?S--S?HHHHHHHHH----TTTS------?S?EE?SSTHHHHT----T?S---EEEE?GG-G????SS??---------SS??S??S?EEEEH---HHHHHT----TT--?-?H-HH----HHHHHHHH-----??T- 3Q8K|A PF00868.15_Transglut_N_seed 50 162 !Q:0,1|7,10|21,21|26,37|46,46|56,61|65,66|73,73|75,76|79,80|82,85|94,94|96,99|103,110|114,114|126,130|137,138|141,143|148,148|152,156 Q:2,6|11,20|22,25|38,45|47,55|62,64|67,72|74,74|77,78|81,81|86,93|95,95|100,102|111,113|115,125|131,136|139,140|144,147|149,151|157,161 ??EEEEE????TTSHHHHHTT?TTSS----------??SEEEETTS?EEEEEEESS?---??TTT??EEEEEE?S--SS??G----GGTSEEEE?E----ESS??------TTS?EEEEEEEETTE-----EEEEEE??TT???EEEE-EEE-----EEEET 1NUG|A PF00869.15_Flavi_glycoprot_seed 35 334 !Q:0,0|5,5|7,8|14,14|17,18|28,29|52,52|72,73|77,81|104,104|107,107|121,121|123,123|125,125|132,133|137,137|146,147|149,152|156,163|166,166|176,176|182,182|186,187|200,202|211,211|214,214|218,218|231,232|234,234|237,242|245,245|248,251|261,263|268,269|273,276|288,288|297,299|302,302|305,318|326,326|330,331|333,333 Q:1,4|6,6|9,13|15,16|19,27|30,51|53,71|74,76|82,103|105,106|108,120|122,122|124,124|126,131|134,136|138,145|148,148|153,155|164,165|167,175|177,181|183,185|188,199|203,210|212,213|215,217|219,230|233,233|235,236|243,244|246,247|252,260|264,267|270,272|277,287|289,296|300,301|303,304|319,325|327,329|332,332 ?GGGG?S??EEEEE?SS??EEEEEEETT??EEEEETTEEEEEEEEEEEEEES?EEEEEEESSEEEEEEEEEE??TTS?????GGGGSTTEEEEEEEEEESGGGT?SS?EEEEEEEEEEEEE?T-T?EEEEEE??TTT?EEEEEEEE??S????TTS------??TT?EEEEEBTTB?EEEEE?GGG--BEEEEEEEGGGS???TTEEEEES?TT?TTS?SEEEEEHHHHHT??S?EE-----?TT?SS---?BTGGGGEEE???BTTB??EEE????HHHHHHHTTTS?EEEEETTE---EE?SS-------------?EEEEEEE?TTB??S? 1N6G|A PF00870.13_P53_seed 7 198 !Q:0,7|9,9|14,14|18,24|28,28|42,42|45,46|53,53|56,58|61,61|79,82|88,88|95,95|98,98|101,101|108,108|111,111|116,116|120,121|128,132|135,135|137,137|145,145|147,147|150,150|157,158|167,167|171,171|183,183|185,185 Q:8,8|10,13|15,17|25,27|29,41|43,44|47,52|54,55|59,60|62,78|83,87|89,94|96,97|99,100|102,107|109,110|112,115|117,119|122,127|133,134|136,136|138,144|146,146|148,149|151,156|159,166|168,170|172,182|184,184|186,197 ????????B?TTTT?EEE???-???STT?SEEEETTTTEEEE?TT??EEEEEE?SS???TT?EEEEEEEESSTTTTTSB????HHHHH?STTTTT?SS?TT?SEEEES?TT?EEEE?TTT??EEEEEE?????TT?S?EEEEEEE?S?TT?TTTTTT??EEEEEEEE?TTS?EEEEEEEEEEE?S?HHHHHHHHHHHH 1UOL|A PF00871.12_Acetate_kinase_seed 11 404 !Q:7,7|10,10|20,26|38,38|44,44|54,54|60,63|78,78|82,82|84,84|90,91|99,100|104,105|107,107|110,111|143,143|147,149|162,163|168,169|172,172|180,187|205,205|209,209|235,236|244,245|248,250|252,253|266,267|279,279|288,288|290,290|301,301|303,303|330,331|333,333|346,346|357,357|363,363|365,365|370,370|372,375|377,378|381,381|383,383|386,386|393,396 Q:0,6|8,9|11,19|27,37|39,43|45,53|55,59|64,77|79,81|83,83|85,89|92,98|101,103|106,106|108,109|112,142|144,146|150,161|164,167|170,171|173,179|188,204|206,208|210,234|237,243|246,247|251,251|254,265|268,278|280,287|289,289|291,300|302,302|304,329|332,332|334,345|347,356|358,362|364,364|366,369|371,371|376,376|379,380|382,382|384,385|387,392|397,403 EEEEEEE?SS?EEEEEEETT-------TTEEEEEEEEE?TTSSS?EEEEEETTS?EEEEE????SHHHHHHHHHHHHT?TTT?S?SSGGG??EEEEEES??TTT??S?EE??HHHHHHHHHTGGGSTTTHHHHHHHHHHHHHH?TTS?--EEEEETTGGGGG??HHHH??SS?HHHHHHH????????HHHHHHHHHHHHHHHTS?GGG?EEEEEEESSSEEEEEEETTEEEEES??SSTTSSS??SS???S??TTHHHHHHHHHT??HHHHHHHHHHS?HHHHHHSS?S?HHHHHHHHHT-T?HHHHHHHHHHHHHHHHHHHHHHHHTT--S?SEEEEEHHHHHH?HHHHHHHHTT?GGGTB?B?TTGG-G--??S??EE?B?TT?SBEEEE????HHHHHHH 2IIR|A PF00873.14_ACR_tran_seed 16 1088 !Q:0,0|7,7|30,30|32,32|35,37|39,40|48,48|51,52|68,69|71,71|94,94|97,98|118,118|122,122|126,127|133,133|136,136|146,152|157,157|187,189|197,197|206,207|220,222|229,229|232,233|236,239|244,249|257,257|262,267|271,271|287,287|290,290|297,297|311,312|331,334|376,376|404,405|407,407|439,439|441,443|445,453|485,486|523,527|530,531|536,543|571,571|585,585|594,594|596,596|599,603|612,613|616,617|645,645|650,650|653,653|656,658|670,671|676,676|681,681|700,700|705,705|707,709|714,718|721,722|729,730|733,734|752,752|757,761|763,763|768,770|779,779|788,789|803,804|824,824|837,837|841,841|845,850|866,866|882,883|885,887|891,891|906,907|909,909|917,917|924,924|926,929|951,951|978,979|981,981|1014,1016|1049,1050 Q:1,6|8,29|31,31|33,34|38,38|41,47|49,50|53,67|70,70|72,93|95,96|99,117|119,121|123,125|128,132|134,135|137,145|153,156|158,186|190,196|198,205|208,219|223,228|230,231|234,235|240,243|250,256|258,261|268,270|272,286|288,289|291,296|298,310|313,330|335,375|377,403|406,406|408,438|440,440|444,444|454,484|487,522|528,529|532,535|544,570|572,584|586,593|595,595|597,598|604,611|614,615|618,644|646,649|651,652|654,655|659,669|672,675|677,680|682,699|701,704|706,706|710,713|719,720|723,728|731,732|735,751|753,756|762,762|764,767|771,778|780,787|790,802|805,823|825,836|838,840|842,844|851,865|867,881|884,884|888,890|892,905|908,908|910,916|918,923|925,925|930,950|952,977|980,980|982,1013|1017,1048|1051,1087 ?HHHHHH?HHHHHHHHHHHHHHHHHHHHHS?B?SS???S??EEEEEEE?TT??HHHHHTTTHHHHHHT??S?TTEEEEEEEEETTSEEEEEEEE?TT??HHHHHHHHHHHHHHHGGGS?HHH-HHT??EEEEB?SS?SEEEEEEES-------SSSS?HHHHHHHHHHHTHHHHHHSTTEEEEEESS-??EEEEEEE?HHHHHHTT??HHHHHHHHHHHS???EEEEET?SS??TT????EEEE??????SHHHHHT?EEEE-----?SSS?EEEGGGTEEEEEEES?SS?EEEETT-EEEEEEEEEEBTT??HHHHHHHHHHHHHHHGGG--??TTEEEEEEEESHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?SHHHHHHHHHHHHHHHHHHHHHHHHTT??B?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-S???H---------HHHHHHHHHHHHHHHHHHHHHHHHHHGGGGG??STHHHHHHHHHHHHHHHHHHHHHHHTTTHHHHHHHH?????TT??SSSS-------?SHHHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHH-HHHHHHHS?B?SS?????SEEEEEEE??TT??HHHHHHHHHHHHHHHHHTTTTTEEEEE-EEES?BT-TB--?SSSEEEEEEEE??TTSS?SGGG-SHHHHHHHHHHHHTTSTT?EEEE-E???SSTT--???TT??EEEEEE-?SS??HHHHHHHHHHHHHHHHT?TTTB----?S?EESS???EEEEEEEE?HHHHHHHT??HHHHHHHHHHHHH?-EEEEEEESSSSEEEEEEEE?GGGSSSGGGGGG?EEE?TTS?-----EEETTTSEEEEEEEE?SEEEEETTEEEEEEE??B--?SSS?HHHHHHHHHHHHHT--S?TTEEEEE?GGGTTT?S????HHHHHHHHHHHHHHHHHHHHT?SSTTHHHHTTTHHHHHHHHHHHHHTT??B?HHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTS???HHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHH??STTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 1OY6|A PF00874.15_PRD_seed 211 117 !Q:7,11|16,26|39,40|46,46|51,65|69,69|76,77|96,101|110,110 Q:0,6|12,15|27,38|41,45|47,50|66,68|70,75|78,95|102,109|111,116 HHHHHHH-----HHHH????------?THHHHHHHHHHH--HHHHH-HHTT----------?????TTH-HHHHHH?-HHHHHHHHHHHHHHHHHH-?????HHHHHHHH-HHHHHH 1TLV|A PF00875.13_DNA_photolyase_seed 143 279 !Q:6,6|8,10|14,14|19,22|25,30|34,39|41,47|53,54|57,57|62,79|81,81|84,85|91,92|106,109|114,116|118,118|125,133|140,143|146,146|149,156|160,161|168,170|189,197|199,199|202,203|207,208|210,210|214,217|221,232|236,239|252,260|262,278 Q:0,5|7,7|11,13|15,18|23,24|31,33|40,40|48,52|55,56|58,61|80,80|82,83|86,90|93,105|110,113|117,117|119,124|134,139|144,145|147,148|157,159|162,167|171,188|198,198|200,201|204,206|209,209|211,213|218,220|233,235|240,251|261,261 EEEEES-S???SSS?HHHH----HH------HTT---?--S?------EEEEE--EE?HHHH------------------T?TT??HHHHH--HHHHHHHHHHHHH----HHHT---S?EEEEES-?-------HHHHHH----HH-HH--------HTT-?SEEEEE???SHHHHHHHHHHHHHHHHT---------T?EE--EEE??S-SSS?---TTT?-?-----?---TTS-???SSHHHHHHHHHH---------S?-------????????? 2WQ6|A PF00877.14_NLPC_P60_seed 28 169 !Q:1,2|5,5|8,10|14,14|17,17|24,24|28,28|41,41|43,46|53,69|76,77|83,84|87,87|94,98|101,101|109,124|141,150|154,156|160,160|168,168 Q:0,0|3,4|6,7|11,13|15,16|18,23|25,27|29,40|42,42|47,52|70,75|78,82|85,86|88,93|99,100|102,108|125,140|151,153|157,159|161,167 T?-BB?TT???SSS?EE?SGGGGG?EEB?HHHHHHHHHHTT-T????SSHHHH-----------------TTSSEE--EEGGG??TT?EEEESG-----GG?SEEEEEE----------------ETTEEEEEEETTTEEE----------EEE???TTB?SEEEESS? 4FDY|A PF00878.13_CIMR_seed 12 163 !Q:0,3|12,12|15,22|30,35|49,49|52,53|57,59|63,63|66,68|72,72|76,77|81,84|87,87|89,91|94,98|103,103|107,109|118,119|122,122|130,130|132,132|139,140|142,143|146,146|157,157 Q:4,11|13,14|23,29|36,48|50,51|54,56|60,62|64,65|69,71|73,75|78,80|85,86|88,88|92,93|99,102|104,106|110,117|120,121|123,129|131,131|133,138|141,141|144,145|147,156|158,162 ????EEEEEEEE?SS?--?---?EEEEEEE------TTEEEEEEEEGGG?TS??SSB???EEE?TT?-?EEE?GGG??SSB---?EE?B???SS---?-EEEE?SSB???SSTTTTTS?-TT?SEEEESS-S?EEEEEB??S??EE?STTEEEEEEE?SGGGT 2KVA|A PF00881.19_Nitroreductase_seed 141 344 !Q:3,4|6,11|13,13|15,24|28,30|39,55|58,63|65,66|70,81|87,96|101,107|122,126|129,130|132,132|135,136|150,166|173,174|177,177|194,194|201,241|247,248|254,256|268,269|276,276|286,292|298,307|313,313|315,318|321,328|333,334|340,341|343,343 Q:0,2|5,5|12,12|14,14|25,27|31,38|56,57|64,64|67,69|82,86|97,100|108,121|127,128|131,131|133,134|137,149|167,172|175,176|178,193|195,200|242,246|249,253|257,267|270,275|277,285|293,297|308,312|314,314|319,320|329,332|335,339|342,342 HHH??B?--?-?B?S??------??HHH---HHHHHHHH-----------------TT------S??GGG?----???----EEEEE---------?HHHH-------HHHHHHHHHHHHTT?????SS??S?SS??TTHHHHHHHHHHH-----------------HHHHHT??TT?HHHHHHHHHHGGGGGG?SEEEEE-----------------------------------------EEETT??THHHH---HHHHHHHHHHH--HHHTTT?EEEEEGGGG-------GGHHH----------HHHHH-T??--TT--------EEEE--EEEEE--E? 1F5V|A PF00882.13_Zn_dep_PLPC_seed 152 330 !Q:11,15|18,18|22,23|26,29|31,31|58,74|77,78|81,81|85,95|100,100|103,103|115,116|118,119|122,127|144,169|171,171|195,219|223,224|228,230|245,271|275,276|278,279|282,282|285,290|300,300|302,310 Q:0,10|16,17|19,21|24,25|30,30|32,57|75,76|79,80|82,84|96,99|101,102|104,114|117,117|120,121|128,143|170,170|172,194|220,222|225,227|231,244|272,274|277,277|280,281|283,284|291,299|301,301|311,329 HHHHHHHHHHH-----HH-HHH??TT----S?HHHHHHHHHHHHTHHHHHHHHHGGGG----------------?TT??TT?GGG---------??BTTT-TB?HHHHSGGGGGG??S??HH------HHHHHHHHHHHHHHHH--------------------------T?HHHHHHHHHHHHHHHHHHTSHHH-------------------------HTT??TTT--?HHHHHHHHHHHHHG---------------------------GGG??S??SS?TT------SHHHHGGGS?S?--------HHHHHHHHHHHHHHHHHHH 2WXT|A PF00883.16_Peptidase_M17_seed 17 333 !Q:10,10|14,14|32,32|41,41|50,50|61,62|65,66|75,82|85,87|99,100|104,108|137,137|139,139|152,153|157,159|162,162|166,166|170,170|174,174|176,176|179,180|193,193|197,198|206,208|226,226|242,243|247,250|253,253|259,261|268,269|271,273|277,278|291,291|294,296|298,298|304,304|311,311|314,318|320,320|323,324 Q:0,9|11,13|15,31|33,40|42,49|51,60|63,64|67,74|83,84|88,98|101,103|109,136|138,138|140,151|154,156|160,161|163,165|167,169|171,173|175,175|177,178|181,192|194,196|199,205|209,225|227,241|244,246|251,252|254,258|262,267|270,270|274,276|279,290|292,293|297,297|299,303|305,310|312,313|319,319|321,322|325,332 HHHHHHHHHS?TTT?SHHHHHHHHHHHHHHTT-TTEEEEEE?HHHHHHTT?HHHHHHHHTS--SS??EEEEEEEE???----?TT???EEEEEEEEEEE??TTS??--?STTGGGGGGGGHHHHHHHHHHHHHHHHT?S-SEEEEEEEEEEE??STT???TT?EEE?TTS?EEE?S?TT??HHHHHHHHHHHG-GGG??SEEEEEE???HHHHHHHTTTSEEEEES?HHHHHHHHHHHHHHT??EEE????HH-HHGGG??-SSSSEE--S???STT--HHHHHHHHHHTT?TT---S?EEEEE?TTTSEE?GG-----G?EE??TTHHHHHH 2EWB|A PF00884.18_Sulfatase_seed 59 610 !Q:0,0|10,11|14,18|24,25|27,51|55,63|68,69|80,83|85,85|99,99|105,105|108,108|112,113|119,119|122,122|126,127|131,132|141,141|143,143|151,152|154,154|161,184|186,186|191,191|194,194|199,199|202,204|207,214|219,219|225,228|230,280|287,287|289,291|294,295|309,312|316,316|320,320|327,328|333,343|345,351|369,381|397,397|400,423|426,427|432,432|469,469|479,479|484,490|494,494|498,498|509,518|528,532|547,547|550,550|559,560|565,565|570,581|586,588|591,594|607,607|609,609 Q:1,9|12,13|19,23|26,26|52,54|64,67|70,79|84,84|86,98|100,104|106,107|109,111|114,118|120,121|123,125|128,130|133,140|142,142|144,150|153,153|155,160|185,185|187,190|192,193|195,198|200,201|205,206|215,218|220,224|229,229|281,286|288,288|292,293|296,308|313,315|317,319|321,326|329,332|344,344|352,368|382,396|398,399|424,425|428,431|433,468|470,478|480,483|491,493|495,497|499,508|519,527|533,546|548,549|551,558|561,564|566,569|582,585|589,590|595,606|608,608 ?EEEEEEESS??TT----?SGGGT??S-------------------?----?HHH---------HHHH--HHSEEESSEE--??S-SHHHHHHHHTTSS?HHHHT?SS?GGG??TTTTT?TT?SSS??SSS??HHHHHHTT-T?EEEEEEE??S?SSGGGS------------------------T-TTTT?SE-EEEE?SS???TT?--?????STTS?HHHHT????E---------------------------------------------------EETTEE?S???TT??HHHHHHHHHHHHH----HTS?TTS?EEEEEE??TTSS-----------S?---???HHHHGGGTTTTTTHHHH-------------HHHHHHHHHHHHTSS?TT???????----------------?SS??GGGS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?GGGEEEEEE-ESSS?--????GGG?GGG?SSHHHHHHHH??-------?SGGGTTSTT?????HHHHHHHHHTTSSS?TT-SSSHHHHB??EEEE?TTSS??----------SSEE???EE----GGGHHHHHHHHH-T? 1N2K|A PF00885.14_DMRL_synthase_seed 104 175 !Q:0,0|3,4|11,11|33,35|59,59|62,62|64,76|84,84|88,89|107,108|111,115|120,120|122,122|131,131|133,133|144,145|149,151|167,174 Q:1,2|5,10|12,32|36,58|60,61|63,63|77,83|85,87|90,106|109,110|116,119|121,121|123,130|132,132|134,143|146,148|152,166 ?TT??EEEEEE?TTHHHHHHHHHHHHHHHHHTT-??TTSEEEEEESSGGGHHHHHHHHH-TT-T----?-------?SEEEEEE-EEE??SSTHHHHHHHHHHHHTT--TG-----GGSS?S?EEEEEEEE-S?HHHHHHHEEE--TTE---EHHHHHHHHHHHHHT?---???? 2VI5|A PF00886.14_Ribosomal_S16_seed 158 102 !Q:1,1|7,8|10,11|19,19|22,22|24,25|29,36|38,40|42,86|98,98|100,101 Q:0,0|2,6|9,9|12,18|20,21|23,23|26,28|37,37|41,41|87,97|99,99 B?SBTTB??B??EEEETTS?SS-S??SEE????????S?-?S?---------------------------------------?????HHHHHHHHTTT?B?? 3KIX|p PF00887.14_ACBP_seed 101 132 !Q:0,2|14,14|17,27|44,45|47,50|52,57|60,73|88,89|92,101|116,119|123,128|131,131 Q:3,13|15,16|28,43|46,46|51,51|58,59|74,87|90,91|102,115|120,122|129,130 ???SHHHHHHHHTT?SS--------???HHHHHHHHHHHHHHHT?-S??--S???--?SS--------------GGGTHHHHHHHHTT--TT?--------?HHHHHHHHHHHHHH----HHH------HT? 2ABD|A PF00888.17_Cullin_seed 47 1105 !Q:5,5|8,12|15,16|20,31|34,37|53,98|101,102|111,114|117,125|132,132|140,161|171,172|188,188|193,194|197,198|202,202|204,227|242,242|246,247|264,265|269,277|292,317|348,349|370,377|381,381|387,388|407,411|422,423|443,443|445,446|457,458|471,554|559,559|562,564|588,594|597,599|621,632|652,664|667,685|700,700|702,702|722,726|740,768|771,771|797,797|803,805|807,863|869,870|877,882|884,902|904,908|925,925|928,935|941,941|945,945|957,1001|1019,1034|1047,1049|1052,1053|1058,1058|1061,1061|1072,1072|1074,1080|1084,1085|1089,1092|1100,1101|1103,1104 Q:0,4|6,7|13,14|17,19|32,33|38,52|99,100|103,110|115,116|126,131|133,139|162,170|173,187|189,192|195,196|199,201|203,203|228,241|243,245|248,263|266,268|278,291|318,347|350,369|378,380|382,386|389,406|412,421|424,442|444,444|447,456|459,470|555,558|560,561|565,587|595,596|600,620|633,651|665,666|686,699|701,701|703,721|727,739|769,770|772,796|798,802|806,806|864,868|871,876|883,883|903,903|909,924|926,927|936,940|942,944|946,956|1002,1018|1035,1046|1050,1051|1054,1057|1059,1060|1062,1071|1073,1073|1081,1083|1086,1088|1093,1099|1102,1102 HHHHH-HH-----HH--HHT------------TT????HHHHHHHHHHHHHHH????????????---------------???????????????????TT--HHHHHHHH----HH---------HHHHHH-HHHTTTT?--------------------?SSHHHHHHH--HHHHHHHHHHHHHHH-HTHH--HH--HTT-T???????????------------?HHHHHHHHHHHHHH-TTT--GGGTHHHHHHHHHHHH--HTT???---?--THHHHHHHHHHHHT???????????------------???HHHHHHTHHHHHHHHHHHHHHHHHHHHHHS-?HHHHHHHHHHHHHHHHHHHH--------TTS?GGGHH--HHHHHHHHHHTTTSHHHH-----HHHHHHHHHS??TTHHHHHHHHHTTSTTTTH-H--HHHHHHHHHH--HHHHHHHHTTTT------------------------------------------------------------------------------------HHHH?HH---HHHHHHHHHHHHHHHHHHTTTTT------?HH---HHHHHHHHHHHHHHSSHHHHH------------TTSTTHHHHHHHHHHHHHH????----?????HH-------------------HHHHHHHHHHHHHH?S?HHHHHHHHHHHHHHHHHSS????-HHHHHHHHHHHHH-----------------------------HS?SHHHHHHHHHHHHHHHHHHHHHHHH-HHHHT---S???------------------------------------------------------SSEEE??EEEGGG??????S?--------------????H-----HHHHHHHHHHHHHHHH?TT--------EEEEE?GGG?EEEEEETTSSS?-------------------------------------------?EEEEEHHHHHHHGGGGT---------------?SEEEHHHHHHHT???HH--HHHH-HH-HHHHHHTSEE?S-------SSS??GGG????TTSEEEE??S?? 3DPL|C PF00889.14_EF_TS_seed 168 459 !Q:0,1|10,11|16,23|33,33|39,39|55,67|69,73|76,77|81,91|95,105|120,120|122,123|128,129|131,131|136,142|152,165|177,178|180,188|202,206|215,215|221,222|226,253|256,268|276,314|316,319|321,374|376,378|382,385|388,392|403,409|419,419|421,422|424,424|439,449 Q:2,9|12,15|24,32|34,38|40,54|68,68|74,75|78,80|92,94|106,119|121,121|124,127|130,130|132,135|143,151|166,176|179,179|189,201|207,214|216,220|223,225|254,255|269,275|315,315|320,320|375,375|379,381|386,387|393,402|410,418|420,420|423,423|425,438|450,458 ??EEEEEEEE--ETTE--------EEEEEEEES?HHHHT?HHHHHHHHHHHHHHH-------------H-----TT??SHH-----------HHH-----------HHHHHHHHHHHHHH?S??EEEE--E-EEEE?------SEEEEEEET--------------TTEEEEEEETT??H---------HHHHHHHHHHHTT??---SBSSGGGS?HHHHH--HHH----------------------------HH-------------HHHHHHH---------------------------------------T----T??----------------------------------------------------H---HHH----HH-----HHHHHHHHHH-------HHTBGGGSB?T--T-STTSBHHHHHHHTT?-------???EEEEEETTT 1AIP|C PF00890.19_FAD_binding_2_seed 63 708 !Q:5,6|20,20|23,25|33,33|38,39|44,46|48,48|51,56|58,61|63,65|78,83|86,86|88,89|96,96|100,100|113,116|118,121|123,144|148,155|157,157|160,162|165,165|173,208|210,212|215,216|220,227|241,242|246,251|265,270|272,278|281,284|295,304|307,308|311,314|318,318|320,320|325,329|332,350|358,358|360,360|362,364|375,377|381,382|385,385|391,391|393,393|395,398|401,409|411,412|420,430|434,435|439,442|448,464|472,472|482,482|489,490|493,497|501,501|507,507|510,558|560,560|568,568|580,589|594,621|624,637|639,640|643,644|648,649|654,654|662,670|685,685|690,692|694,695|701,702|705,705 Q:0,4|7,19|21,22|26,32|34,37|40,43|47,47|49,50|57,57|62,62|66,77|84,85|87,87|90,95|97,99|101,112|117,117|122,122|145,147|156,156|158,159|163,164|166,172|209,209|213,214|217,219|228,240|243,245|252,264|271,271|279,280|285,294|305,306|309,310|315,317|319,319|321,324|330,331|351,357|359,359|361,361|365,374|378,380|383,384|386,390|392,392|394,394|399,400|410,410|413,419|431,433|436,438|443,447|465,471|473,481|483,488|491,492|498,500|502,506|508,509|559,559|561,567|569,579|590,593|622,623|638,638|641,642|645,647|650,653|655,661|671,684|686,689|693,693|696,700|703,704|706,707 SEEEE??STHHHHHHHHHHH-HT?-?EEEEESS?GGGS--GGGG?-?S?EE???-??S----S???HHHHHHHHHHHT------TT?S-?HHHHHH-HHH-HHHHHHHHHHTT----T????B---------------------?SSS-------?B?EE??-TT?BSTTTTS-----------------------------------?B???EE?-STT?-------HHHHHHHHHHHHH--TTS?----?EEEETEEEEEEEE------E-------TT----EEEEEEEEET----------TT??EE----EEE?S-EEEE?????GG-------------------GSSSBSS?T-T???HHHHHHHHTT??-EES--TT?EEEES?B?T----TT??-------B??THHHHHT----------?EEE?-SSS??--STTTS----------------?SSSGGGS?HHHHHHHHH-HHHHTT??BT-----TTT?BEEEE?TT-------------------------------------------------S?HHHHHHH?SHHHHHHHHSS?-------??TTTS---------------------------?EE--------------E??EE--EEE??BEEB?TTSEEEE---------EETTEEEEEEEEEE?SSSE---E??SSTTS??TT?HH 2V1D|A PF00891.13_Methyltransf_2_seed 30 287 !Q:1,1|3,6|9,9|17,17|25,26|30,34|57,58|63,63|65,70|79,81|89,90|92,94|113,113|120,121|126,126|134,134|147,147|157,157|164,174|182,183|186,186|188,194|196,196|199,199|207,207|222,226|230,230|236,236|239,239|242,245|252,259|270,270|273,275 Q:0,0|2,2|7,8|10,16|18,24|27,29|35,56|59,62|64,64|71,78|82,88|91,91|95,112|114,119|122,125|127,133|135,146|148,156|158,163|175,181|184,185|187,187|195,195|197,198|200,206|208,221|227,229|231,235|237,238|240,241|246,251|260,269|271,272|276,286 E?T----TS?EEEEEEE?HHHHHHS??TTS---??THHHHHHHTSHHHHGGGGGHHH--HHHH?S-----?HHHHHHSS?--HHHHGGG-?H---HHHHHHHHHHHHHHHHHH-HHHHHH??TTSS?SEEEEET?TTSHHHHHHHHH?TTSEEEEEE?TTTTTT???-------?TTEEEEE??TT-T????--?S?EE?SSSSTTS?HHHHHHHHHHHHHH??---SSS?EEEEE?EE?SS????HHHHHH--------HHHHHHHHHH?SS???EEHHHHHHHHH 3TKY|A PF00893.14_Multi_Drug_Res_seed 17 107 !Q:0,2|4,6|22,42|47,49|63,70|92,99 Q:3,3|7,21|43,46|50,62|71,91|100,106 ???H---HHHHHHHHHHHHHHH???-------???????????HHHH---HHHHHHHHHHHHH??-?????HHHHHHHHHHHHHHHHHHHHH????????HHHHHHH 3B5D|A PF00897.12_Orbi_VP7_seed 7 356 !Q:0,0|17,18|22,25|44,48|51,52|74,77|79,80|83,86|95,95|99,101|118,120|123,123|126,126|131,131|136,136|140,144|147,147|164,164|167,167|171,171|174,174|181,182|197,197|201,201|205,206|209,209|219,219|223,224|227,227|229,229|233,233|238,239|243,243|258,259|275,276|295,295|299,300|303,305|327,332|335,339|341,343|347,349|354,355 Q:1,16|19,21|26,43|49,50|53,73|78,78|81,82|87,94|96,98|102,117|121,122|124,125|127,130|132,135|137,139|145,146|148,163|165,166|168,170|172,173|175,180|183,196|198,200|202,204|207,208|210,218|220,222|225,226|228,228|230,232|234,237|240,242|244,257|260,274|277,294|296,298|301,302|306,326|333,334|340,340|344,346|350,353 ?HHHHHHHHHHHHHHTT??SSS????HHHHHHHHHHHHHHHHHH?????SS??SHHHHHHHHHHHHHHHHHHHT????S??SS????TTHHHHHT?TTS???HHHHHHHHHHHHHHTS???EE?SS?TTTT?SEEE?TTB??-??TT?SEEEEEEETTEEEEEE?TT?EEE?GG-GTTTSS??SEEEEEEEEEEEEE?TTS?EEE??TT?EEEETTEEE?TTS-?EE-E?SSS?EEEE??SSS?EEEEEEEEEEEESS??TTSSTTHHHHHHHHH??SSHHHHHHHHHHHTTSSS?SSS??SS???SHHHHHHHHHHHHHHHHHHHH??????TT?????S???HHH---HHHT?? 2BTV|C PF00899.16_ThiF_seed 90 221 !Q:2,2|8,9|24,24|26,31|38,40|42,43|50,50|53,54|58,59|61,63|66,67|81,81|83,83|87,88|92,95|97,97|99,120|129,135|137,138|141,142|144,148|153,162|165,166|176,177|183,195|197,202|210,210|217,217 Q:0,1|3,7|10,23|25,25|32,37|41,41|44,49|51,52|55,57|60,60|64,65|68,80|82,82|84,86|89,91|96,96|98,98|121,128|136,136|139,140|143,143|149,152|163,164|167,175|178,182|196,196|203,209|211,216|218,220 HH?EEEEE??SHHHHHHHHHHHHH-T?-----SEEEEE???B??GGGGGT?TT??GGG--T---TS--BHHHHHHHHHHHH?T-TSE--EEE----E?S??-------------------?HHHHHHHH-------H--TS--S-----EEEE?--------?SS--HHHHHHHHH--HHHHH-------------T?-?---EEEEEEE-BTEEEE-EEE 3H9J|A PF00900.15_Ribosomal_S4e_seed 81 95 !Q:6,7|10,10|14,14|17,18|21,21|27,27|38,38|42,42|51,51|56,66|69,70|73,73|78,78|80,82|85,92|95,95 Q:0,5|8,9|11,13|15,16|19,20|22,26|28,37|39,41|43,50|52,55|67,68|71,72|74,77|79,79|83,84|93,94 TTTEEE??EE?SSS?EE??EE?TTTTT?EEEEEEEEEE?GGG?EEEEETTS?EEES??---------TT??TT?EEEE?S---SS?------?EE- 2XZM|W PF00902.13_TatC_seed 144 426 !Q:0,1|3,3|24,24|26,29|32,32|35,59|63,73|77,77|80,80|88,88|91,193|196,197|199,200|203,203|207,207|236,236|239,243|245,247|283,285|291,328|331,344|347,347|371,371|381,382|387,387|396,396|411,413 Q:2,2|4,23|25,25|30,31|33,34|60,62|74,76|78,79|81,87|89,90|194,195|198,198|201,202|204,206|208,235|237,238|244,244|248,282|286,290|329,330|345,346|348,370|372,380|383,386|388,395|397,410|414,425 ??T-THHHHHHHHHHHHHHHHHHH-H----TT-TT-------------------------HHH-----------HHH-HH-HHHHHHH?TT?-----------------------------------------------------------------------------------------------------?EE??S--SS?HHH-HHHHHHHHHHHHHTHHHHHHHHHHHHTT-TT-----T???STTHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHT?--STTGG--------------------------------------GG---?----------SS?EEHHHHHHHHHHHHHHHHHHTTH-HHHHHHHHH--HTSS?HHHHHTSH-HHHHHHHHHHHHHH?--SSHHHHHHHHHH 4HTT|A PF00903.20_Glyoxalase_seed 82 326 !Q:6,13|18,18|30,32|34,35|43,43|46,46|59,60|70,70|73,74|76,76|78,79|91,91|94,94|107,109|124,124|128,128|135,135|137,137|139,144|149,149|152,162|165,166|175,175|190,191|205,205|211,211|219,221|223,223|225,225|255,278|281,281|289,313|316,316|318,318|321,321 Q:0,5|14,17|19,29|33,33|36,42|44,45|47,58|61,69|71,72|75,75|77,77|80,90|92,93|95,106|110,123|125,127|129,134|136,136|138,138|145,148|150,151|163,164|167,174|176,189|192,204|206,210|212,218|222,222|224,224|226,254|279,280|282,288|314,315|317,317|319,320|322,325 SEEEEE--------EEES?HHHHHHHHTTT---T??EEEEEEE?SS?TTSEEEEEESTT??TTSEEEEEE?TT??B?B??BSEEEEEEEEE?TT?HHHHHHHHHHTT???EEEEETTEEEEEEE?TTS?EEEEEE?S?S??????BTTB?TT-----------TS??EEEEEEEE?SSHHHHHHHHHHTS??EEEEEETTEEEEE?SSSSS?EEEEESS???B?B?SBTEEEEEEEEESSHHHHHHHHHHHHHTT------------------??????EE?SSSEEEE-------------------------EE?T-TS?EEEE 3LM4|A PF00905.17_Transpeptidase_seed 42 425 !Q:10,10|20,22|25,41|44,45|50,51|56,57|59,60|70,70|79,80|83,83|87,87|101,101|103,111|124,124|132,132|137,137|140,157|159,160|173,178|181,184|186,190|193,230|241,241|243,244|247,247|265,267|271,295|298,301|304,304|306,306|325,333|336,336|340,340|345,346|355,374|383,383|389,390|399,405|408,410 Q:0,9|11,19|23,24|42,43|46,49|52,55|58,58|61,69|71,78|81,82|84,86|88,100|102,102|112,123|125,131|133,136|138,139|158,158|161,172|179,180|185,185|191,192|231,240|242,242|245,246|248,264|268,270|296,297|302,303|305,305|307,324|334,335|337,339|341,344|347,354|375,382|384,388|391,398|406,407|411,424 EEEEEEETTT?BEEEEEEES???TT??---------------SS??GGGG??HHHH??B??GGGGHHHHH-HHHHHTTS??TT?EEE?TTSEEEETTEEEE?S???-----?SEEEHHHHHHHT?HHHHHHH-HHHH?HH------------------H--HHHHHHHTTTTS??????TT????B?-???SS??------------------------------------HHHHHHHHTT?S-?BB?HHHHHHHHHHHHTTTEE???BSB?-----------------------?SS????EE?S?HHHHHHHHHHHHHHHHST---------TS?GGG?BTTB??EEEEEEEE??????????-------???EEEEEEEE-ESSSS??EEEEEEEE----???SS???HHHHTHHHHHHHHH 2Z2M|B PF00906.15_Hepatitis_core_seed 12 265 !Q:0,2|9,10|18,18|23,24|30,30|37,38|48,51|59,62|84,85|96,136|159,159|177,177|182,182|185,264 Q:3,8|11,17|19,22|25,29|31,36|39,47|52,58|63,83|86,95|137,158|160,176|178,181|183,184 ???SGGGGT??HHHHTTS?STTS??HHHHH-HHHHHH--SSTTTSSSS??--SHHHHHH----HHHHHHHHHHHHHHHHHHHTT??STTTHHHHHH-----------------------------------------HHHTHHHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHHHS?GGGS?SS???????????????????-----???????????---------??????????-----------------????????? 3V6Z|E PF00907.17_T-box_seed 22 206 !Q:16,17|21,21|25,25|28,28|31,32|38,42|44,44|61,61|65,66|78,87|90,90|93,93|104,104|107,107|110,110|116,120|124,125|127,129|131,132|147,148|152,162|164,166|172,172|176,176|183,185|196,196 Q:0,15|18,20|22,24|26,27|29,30|33,37|43,43|45,60|62,64|67,77|88,89|91,92|94,103|105,106|108,109|111,115|121,123|126,126|130,130|133,146|149,151|163,163|167,171|173,175|177,182|186,195|197,205 EEEETTHHHHHHHHHH??EEE?BTT?EE?SS??EEEEE?----S?TTSEEEEEEEEEESSS?EEE--EETTEEEEESS??????-???EE?TT?SEEHHHHHHS?EE?TT?EEESS?---?TTT?-E---E??SSSEEEEEEEEEEE--SSS-----------S??-EEEEE?GGG?EEEESS???HHHHHHHHHH?GGGHHHHHH 1XBR|A PF00908.12_dTDP_sugar_isom_seed 19 185 !Q:3,3|8,8|13,14|39,43|53,53|63,63|67,69|86,87|90,90|95,95|106,107|112,112|122,122|126,126|136,138|145,146|149,149|154,158|161,162|164,172|178,180 Q:0,2|4,7|9,12|15,38|44,52|54,62|64,66|70,85|88,89|91,94|96,105|108,111|113,121|123,125|127,135|139,144|147,148|150,153|159,160|163,163|173,177|181,184 EEE?SSTT?EEEE??EEEETTEEEEEEEEHHHHHHHHSS?????EEEEEEEET-TBEEEEEEE?GGG???EEEEEEESEEEEEEEE??TT?TTTT?EEEEEEETTT??EEEE?TTEEEEEEE?SSE-EEEEEEESS???TTTEEE??TT?TTTT?????SS??B-------??HHHHT???GGGS 4HN1|A PF00909.16_Ammonium_transp_seed 25 495 !Q:13,13|26,26|33,34|47,48|63,63|65,68|75,85|89,90|96,97|103,114|125,125|140,140|166,176|178,178|185,197|200,200|204,204|221,223|228,234|237,240|242,242|275,287|311,313|315,319|335,335|342,344|365,369|376,378|381,381|387,389|404,405|410,422|424,426|431,431|433,436|469,471|474,475|482,482|489,489|491,492|494,495 Q:0,12|14,25|27,32|35,46|49,62|64,64|69,74|86,88|91,95|98,102|115,124|126,139|141,165|177,177|179,184|198,199|201,203|205,220|224,227|235,236|241,241|243,274|288,310|314,314|320,334|336,341|345,364|370,375|379,380|382,386|390,403|406,409|423,423|427,430|432,432|437,468|472,473|476,481|483,488|490,490|493,493 HHHHHHHHHHHHH-HHHHHHHHHTTS?GGGHHH--HHHHHHHHHHHH--HHHHHHTHHHHHHS?E----ETTTEE?----------STT--GGGTT??THHHH------------HHHHHHHHHH-HHHHHHGGGGTTTB?HHHHHHHHHHHHHHTHHHHHHHHHS-----------S?HHHHTT??----------?SS?TTT-THHHHHHHHHHHHHHH???TTTT-------TS????S?HHHHHHHHHHHHHHHHHHHHHTTSSSSHHHHH-------------HHHHHHHHHHHHHHHHHHHHHHT---S?--??HHHHHHHHHHHHHHH-TTTTTT??-HHHHHHHHHHHHHHHHHHHH-----HHHHTT???TT?HHHHH---HHHHHHHHHHHHHH??HHHH-------------S???GGGT?H----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?--SB??HHHHHH?HHHHHH-S??S?- 1U77|A PF00910.17_RNA_helicase_seed 99 133 !Q:4,4|8,8|18,18|25,28|31,38|46,47|52,54|63,63|66,67|69,71|79,81|84,84|92,93|106,124|132,132 Q:0,3|5,7|9,17|19,24|29,30|39,45|48,51|55,62|64,65|68,68|72,78|82,83|85,91|94,105|125,131 EEEE?SSS?SSHHHHHHH-HHHHHT---?EE--------EEEEGGG??HHHH---HTTHHHHH-HS??T???EEEEEES???GG-GHHHHHH--HHHHHHHSTTTE-------------------EEEEEES? 2QGZ|A PF00912.17_Transgly_seed 172 339 !Q:0,22|24,31|34,47|49,49|51,54|57,63|73,73|79,84|89,89|97,97|100,124|133,135|137,137|140,149|151,170|172,177|180,182|194,199|203,204|206,206|214,214|219,219|221,222|224,224|226,229|231,231|245,257|261,264|267,271|282,282|285,290|293,297|299,300|303,314|321,324|326,328|333,333 Q:23,23|32,33|48,48|50,50|55,56|64,72|74,78|85,88|90,96|98,99|125,132|136,136|138,139|150,150|171,171|178,179|183,193|200,202|205,205|207,213|215,218|220,220|223,223|225,225|230,230|232,244|258,260|265,266|272,281|283,284|291,292|298,298|301,302|315,320|325,325|329,332|334,338 ??------??????--?-----?S?????-?-GG--------------G-S---?HH-------HHHHHHHHH?TTTTT------SSSS?HHHHHHH-HH???-?---?????-------?????HHHHHHHT---T-SS----------S-------??-----??----H------HH---HHHHHHHHHHH------HHH--S?HHHHHHH-HHHH?B?-S-T----T?BHHHHHHHHHHSS------------?GGG--??HH-----HHHHHHTSTT?TT------TS----?T--TT-----?------HHHHHH----H---HHHH-HHHHH 3NB6|A PF00913.14_Trypan_glycop_seed 63 457 !Q:0,23|28,28|31,31|45,45|78,81|101,103|142,144|148,148|156,158|162,162|169,170|173,180|189,191|193,206|214,214|217,229|231,231|243,243|247,252|260,260|264,274|277,277|282,282|289,294|298,300|303,305|308,311|314,314|327,335|338,340|348,350|352,352|369,375|378,379|402,405|412,412|414,414|416,417|422,426|429,431|435,435|437,439|441,441 Q:24,27|29,30|32,44|46,77|82,100|104,141|145,147|149,155|159,161|163,168|171,172|181,188|192,192|207,213|215,216|230,230|232,242|244,246|253,259|261,263|275,276|278,281|283,288|295,297|301,302|306,307|312,313|315,326|336,337|341,347|351,351|353,368|376,377|380,401|406,411|413,413|415,415|418,421|427,428|432,434|436,436|440,440|442,456 ----------------------??SEEE?HH-HHHHHHHHHHHTT-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH----HTTTSHHHHHHHHHHHHHH---HHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHH---HHH?EEETTEE---SBB?TTSSSB??EE--------TTEETTEE???S???????---????SSSBTTB?TT????---------S?HHHHTEEEEEE?GGG-----?SSTTTSS?SSS?---------?SS?EEET-TTTEEE?-----SSS???EE???SS????SS?TTHHHHHHHHHH---------HT???TTSGGGS???S?GGGSSSHHHHHHHTTS-----??SS??HHHHHHHHHHHHSSSSHHHHHH----HHHHHH-H?B??GGGS----?TT???BGG-G???H-HHHHHHHHHHHHHHH 2VSG|A PF00915.15_Calici_coat_seed 11 313 !Q:0,38|40,45|55,56|58,63|69,70|81,81|85,85|88,88|95,95|115,116|125,126|131,131|139,139|143,148|164,164|167,167|173,176|180,180|184,184|188,190|197,197|199,200|203,203|206,209|212,213|223,223|226,226|229,230|232,233|235,236|239,239|243,254|258,258|260,260|265,265|267,268|273,274|277,279|281,282|286,286|288,288|292,292|294,294|297,298 Q:39,39|46,54|57,57|64,68|71,80|82,84|86,87|89,94|96,114|117,124|127,130|132,138|140,142|149,163|165,166|168,172|177,179|181,183|185,187|191,196|198,198|201,202|204,205|210,211|214,222|224,225|227,228|231,231|234,234|237,238|240,242|255,257|259,259|261,264|266,266|269,272|275,276|280,280|283,285|287,287|289,291|293,293|295,296|299,312 ??????--------????????????????????-????S??????TTSGGGTSS??B???---TTTTT??EEEEEEEEEE?TTS?TT?EEEEEE?SGGGSHHHHHHHTTBSEEE??EEEEEEEE??SSEE?EEEEEEE?TTS??????HHHHTTSSEEEEETT?SS?EEEEE????SSS?EES?TTS???EEEEEE?S??EE?SS??--TT??EEEEEEEEE?TT?EE??B??T--TT?STT??---???????GGG?B?SSSS?B??EEEE??TT???B??SSS?B?TTS?B?TT??SSGGGTTEEEEEEE 1POV|3 PF00917.21_MATH_seed 52 209 !Q:1,1|3,3|9,13|16,16|20,22|25,25|27,27|30,30|34,51|56,57|59,62|74,75|80,88|91,91|94,95|104,107|110,118|122,127|134,135|138,138|140,140|144,144|149,149|154,154|159,159|162,163|176,180|192,193 Q:0,0|2,2|4,8|14,15|17,19|23,24|26,26|28,29|31,33|52,55|58,58|63,73|76,79|89,90|92,93|96,103|108,109|119,121|128,133|136,137|139,139|141,143|145,148|150,153|155,158|160,161|164,175|181,191|194,208 E?S?GGGTT----?TT?EEE???EE?T-TS?EEE------------------EEEE??S----SSEEEEEEEEE??TTGG---------GS?SS??SEEEEEEE????SS---------GGG???---EEEEEE??TT?B?TTS?BTTS?HHHH?EEEE?TT??EEEEEEEEEEEE-----EEEHHHHTSTT--SSBTTBEEEEEEEEE 1LB4|A PF00919.15_UPF0004_seed 160 156 !Q:0,0|5,6|8,8|26,26|28,32|35,36|38,40|48,49|70,74|77,81|83,113|117,127|136,136|138,139|146,146|148,148|151,151|155,155 Q:1,4|7,7|9,25|27,27|33,34|37,37|41,47|50,69|75,76|82,82|114,116|128,135|137,137|140,145|147,147|149,150|152,154 ?EEEE??S?HHHHHHHHHHHHHTTTS-S?????SS--S-??SEEEEEE??SSSSHHHHTHHHHHHHHTTS-----TT-----T?-----------------------------?EEE-----------EEEHHHHS?H--HHHHHH?T-TS?EEE? 4JC0|A PF00920.16_ILVD_EDD_seed 89 761 !Q:0,45|51,53|55,63|89,92|99,100|119,119|123,178|184,195|203,203|208,208|214,221|229,229|231,231|238,238|240,245|247,247|265,266|269,270|274,274|276,286|308,309|323,325|328,334|336,336|346,347|349,349|351,352|356,356|358,358|360,362|383,383|385,389|391,394|399,404|407,407|416,417|420,430|434,434|439,445|448,449|452,452|454,454|457,488|491,492|496,496|500,501|503,505|516,517|522,522|526,526|528,533|539,549|567,567|577,584|589,589|591,591|597,597|599,600|602,605|619,620|629,629|633,634|637,637|645,645|649,649|651,651|656,657|660,660|665,666|670,671|678,679|681,681|685,693|695,698|701,724|727,731|737,740|744,744|753,755 Q:46,50|54,54|64,88|93,98|101,118|120,122|179,183|196,202|204,207|209,213|222,228|230,230|232,237|239,239|246,246|248,264|267,268|271,273|275,275|287,307|310,322|326,327|335,335|337,345|348,348|350,350|353,355|357,357|359,359|363,382|384,384|390,390|395,398|405,406|408,415|418,419|431,433|435,438|446,447|450,451|453,453|455,456|489,490|493,495|497,499|502,502|506,515|518,521|523,525|527,527|534,538|550,566|568,576|585,588|590,590|592,596|598,598|601,601|606,618|621,628|630,632|635,636|638,644|646,648|650,650|652,655|658,659|661,664|667,669|672,677|680,680|682,684|694,694|699,700|725,726|732,736|741,743|745,752|756,760 ???????????-----------????????????????????????EEEEE???B?????????SSSGGGGHHHHHHHHHHHHHHHHTT??-?SEEEEE??STTTTHHHHHHHHTTTTS?EEE???????????-------------------------??????????-??----???THHHH------------HHHTTSS?HHHH-HHHHH????????HHHHHTT?S?TTGGGS?T------T?HHHHHHHHHHHHHHHHT--ST--TSS-S-------???-HHHHSSHHHHHHHHHHHHHTT??THHHHHHHHHHHH---TT??---??H-HHHHHHHTT??B?B??GGG-S-S??-HHHHHHHTHHHHHHHHHHHH-T--?--S????EETT------EE?GGGGGEEE--EE-----------ETT-EEEE-------EE??SS?S?TT--------------------------------TB??SSS?SBS--S?-?EEEEEETTEE--EEEE?TTS?G------GGSEE-----------EEEEEEESSGGGHHHHH-HTTTTSSSE--------EEEE?S?SHHHH-S??B--??SSHHHHHHHHHTT??EEEEESSB?SSS??SS?EEEEEES?GGG-T?GGGT??TT?EEEE--ETT--TTEEEE?-S?HHH---------H----HH-???-------????-?-------GG-----GSSST----TGG-GSHHHHHT???GGGTS 2GP4|A PF00921.12_Lipoprotein_2_seed 16 199 !Q:8,8|11,20|25,27|29,32|44,45|49,53|56,59|72,72|86,89|91,92|94,96|100,101|109,110|112,113|115,116|119,120|143,144|147,148|151,152|155,156|196,198 Q:0,7|9,10|21,24|28,28|33,43|46,48|54,55|60,71|73,85|90,90|93,93|97,99|102,108|111,111|114,114|117,118|121,142|145,146|149,150|153,154|157,195 HHHHHHHH?SS---------?SSSS--?S????GGGGGGGGGGS??STT??-??HH----HHHHHHHHHHTS?HHHHHHHHHHHTT?---S??S???TTT??SHHHHHH??T--T??SS??SSSSSSHHHHHHHHHHHHHSTT??EE??TT--TH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??? 1L8W|A PF00923.14_Transaldolase_seed 131 475 !Q:4,4|6,6|12,16|19,24|29,30|37,42|46,46|49,49|60,63|70,113|115,115|139,149|152,153|158,159|165,165|184,186|188,189|199,199|201,204|216,216|219,219|221,237|244,244|256,268|270,281|296,296|302,320|324,324|341,341|343,365|371,372|380,381|390,390|393,393|403,403|407,422|424,433|439,440|446,446|459,461 Q:0,3|5,5|7,11|17,18|25,28|31,36|43,45|47,48|50,59|64,69|114,114|116,138|150,151|154,157|160,164|166,183|187,187|190,198|200,200|205,215|217,218|220,220|238,243|245,255|269,269|282,295|297,301|321,323|325,340|342,342|366,370|373,379|382,389|391,392|394,402|404,406|423,423|434,438|441,445|447,458|462,474 EEEE?S?HHHHH-----HH??----SEEE??HHHHHH------HTT-SG-GGHHHHHHHH----HHHHHH?-------------------------------------------S?HHHHHHHHHHHHHHHHHHHHHTT?----------SS-?EEEE??GGGTT?HHHHHHHHHHHHHHHHHT---T??GGGEEEEEE?S----HHHHHHHHHHH-HT-T---------------??EEEEEE?SHHHHHHHHHH-------------T-----------?SEEEEBSHHHHHHH-HHSSS??--------------???GGG?HHHHHHHHHHHHHHHT-T-------------------?-??EEEEB??SSHHHHH--HTTTSSEE-EE?HHHHHHHHH-SBS???-??????------S??????????HHHHH--HHHHT?HHHHHHHHHHHH---HHHHHHHHHHHHH 1I2Q|A PF00924.13_MS_channel_seed 37 286 !Q:21,25|61,62|65,65|68,68|74,88|90,90|98,98|106,106|110,110|123,123|130,132|145,145|149,152|167,167|171,171|173,218|221,221|230,230|245,251|265,273|283,285 Q:0,20|26,60|63,64|66,67|69,73|89,89|91,97|99,105|107,109|111,122|124,129|133,144|146,148|153,166|168,170|172,172|219,220|222,229|231,244|252,264|274,282 HHHHHHHHHHHHHHHHHHTTT??---STTHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHTT?-SS?TT?EEESS---------------S?EEEEEEE?SSEEEEE?TTS?EEEEEHHHHHTS?EEESSS---SSEEEEEEEEEE?TTS?---HHHHHHHHHHHHHH?TTB?T----------------------------------------------TS?EEEEEEEE?SSSEEEEEEEEEET-------TTHHHHHHHHHHH---------HHHHHHHHT??? 4AGE|A PF00925.15_GTP_cyclohydro2_seed 161 265 !Q:13,17|19,21|30,33|39,39|42,44|51,65|74,75|82,83|85,87|89,89|105,138|140,140|142,147|154,212|223,223|225,230|233,233|237,237|239,249|253,255|258,260|262,264 Q:0,12|18,18|22,29|34,38|40,41|45,50|66,73|76,81|84,84|88,88|90,104|139,139|141,141|148,153|213,222|224,224|231,232|234,236|238,238|250,252|256,257|261,261 EEEEEEEEEEETT-----E---EEEEEEEE----ETTSS?EE---EEEEES-------??-?????SEEEEEEE??HHHHTT??T---T?SHHHHHHHHHHHHHH----------------------------------H-T?-----EEEEEE??---?????????---?????????-??-?????????????-------???????-?HHHHHHHHTT?S------EE-EEB?S??-?-??????TTT--?EE???B-?? 2BZ1|A PF00926.14_DHBP_synthase_seed 97 255 !Q:10,10|12,13|18,18|20,29|39,40|54,55|60,60|69,70|73,112|115,116|119,119|122,124|126,129|132,133|147,158|161,164|175,175|179,180|187,189|203,205|207,207|216,218|220,220|223,223|226,227|231,232|242,243 Q:0,9|11,11|14,17|19,19|30,38|41,53|56,59|61,68|71,72|113,114|117,118|120,121|125,125|130,131|134,146|159,160|165,174|176,178|181,186|190,202|206,206|208,215|219,219|221,222|224,225|228,230|233,241|244,254 HHHHHHHHHT-T??EEEE?S??----????EEEEEESTT??HHHHHHHHHHTBS??BEEE?HHHHHHTT??BS??--?------?????---------------------???BB??EE-ET---T---?SS??SHHHHHHHHHHHT-----------?SS--??GGGEEEEEEE?EEE??TTGGGT???HHHHHHHHHHHTT?-?S-BEEEEEBB--?T-TS-SB??HHH--HHHHHHHTT??EEEHHHHHHHH 3MGZ|A PF00927.17_Transglut_C_seed 41 112 !Q:6,7|9,10|12,12|15,16|26,26|30,31|44,44|48,48|64,64|76,76|81,83|87,88|90,95|97,97 Q:0,5|8,8|11,11|13,14|17,25|27,29|32,43|45,47|49,63|65,75|77,80|84,86|89,89|96,96|98,111 EEEEEE??S??B-TT??EEEEEEEEE?SSS?-EEEEEEEEEEEE?TTS?EEEEEEEEEEEEEEE?TTEEEEEEEEE?HHHH---TTT??T------T?EEEEEEEEEETTTT 1NUG|A PF00928.16_Adap_comp_sub_seed 46 669 !Q:0,4|7,14|27,30|32,32|35,35|38,38|40,40|43,46|52,52|55,56|63,64|66,66|68,68|75,75|78,118|120,121|124,128|133,133|141,141|143,143|146,165|167,168|172,174|177,178|183,188|192,194|197,252|255,262|266,266|270,330|333,333|335,336|345,351|353,353|355,355|368,373|376,413|420,422|426,429|439,441|448,451|457,461|463,463|469,522|524,524|529,532|534,584|593,593|595,595|598,627|634,635|637,639|643,646|662,662|667,668 Q:5,6|15,26|31,31|33,34|36,37|39,39|41,42|47,51|53,54|57,62|65,65|67,67|69,74|76,77|119,119|122,123|129,132|134,140|142,142|144,145|166,166|169,171|175,176|179,182|189,191|195,196|253,254|263,265|267,269|331,332|334,334|337,344|352,352|354,354|356,367|374,375|414,419|423,425|430,438|442,447|452,456|462,462|464,468|523,523|525,528|533,533|585,592|594,594|596,597|628,633|636,636|640,642|647,661|663,666 ?????TT-??----?SSEEEEEEEEEE----E-EE-EE?T-TS?---EEEEE-EE??EEEEEE??S-S?EEEEEE?SS??????--------------------------?????????S??SS?????EEEE?TTEEGGG-T-TS--------------------S??EEE???SE--EEEE------EEE---EE-------------------------------------------------------?SS----????EEE-EEE??--------------------------------------------------------?-?TT-T??EEEEEEEE?------S?T-TSEEEEEEEEEE?----?TT--------------------------------------EEEEEE??-SSS----EEEEEGGGT---EEEEEE----EEEET-----T?EEEEE------------------------------------------------------E-EEEE????S--????-------------????----------------------------EEEEEEES-S?TT??---------------------------?EEEEEE--E--?TTT-???GGGEEEEEEEEEEEE-EEEE?? 2JKT|M PF00929.19_RNase_T_seed 57 220 !Q:8,8|10,10|12,24|27,28|42,52|61,61|63,63|66,70|78,80|84,85|89,90|95,96|107,107|109,117|124,125|142,154|167,168|170,182|193,194|198,206 Q:0,7|9,9|11,11|25,26|29,41|53,60|62,62|64,65|71,77|81,83|86,88|91,94|97,106|108,108|118,123|126,141|155,166|169,169|183,192|195,197|207,219 EEEEEEES?S?T-------------TT??EEEEEEEEEETTE-----------EEEEEEEE?B?SS?--??HHHHHHH???HHH--HTT??BHHH--HHHHHHHHSS-S--------?EEEETT--HHHHHHHHHHHHHHHH?????------??EEEHHHHHHHHT??S??-----------SHHHHHHHTT??STT?-------?HHHHHHHHHHHHH 1FXX|A PF00930.16_DPPIV_N_seed 43 532 !Q:0,0|12,19|23,23|27,27|41,48|51,52|55,57|60,72|74,74|79,79|82,83|86,86|99,101|107,110|113,123|130,134|138,139|152,152|156,156|161,170|179,179|182,183|190,191|195,204|207,207|214,218|223,226|236,238|241,242|246,249|253,255|262,264|273,275|278,282|285,286|306,306|308,308|310,324|327,328|331,332|341,341|345,345|348,349|353,356|359,368|380,380|384,388|398,399|401,419|421,423|427,428|432,432|434,440|447,447|457,457|461,465|468,468|478,484|487,487|489,490|498,498|503,505|513,513|516,516|530,530 Q:1,11|20,22|24,26|28,40|49,50|53,54|58,59|73,73|75,78|80,81|84,85|87,98|102,106|111,112|124,129|135,137|140,151|153,155|157,160|171,178|180,181|184,189|192,194|205,206|208,213|219,222|227,235|239,240|243,245|250,252|256,261|265,272|276,277|283,284|287,305|307,307|309,309|325,326|329,330|333,340|342,344|346,347|350,352|357,358|369,379|381,383|389,397|400,400|420,420|424,426|429,431|433,433|441,446|448,456|458,460|466,467|469,477|485,486|488,488|491,497|499,502|506,512|514,515|517,529|531,531 ?TTSSEEEEEEE--------EEE?SSS?EEEEEEEEETTTT--------EE??SS???SS-------------B?EEEE?SS--TT?EEEEETTEEEEE---SSTTS--??EE???--??----BTTTEE-----ESB??HHHHHTTTSSSB?EEE?SSTT----------EEEEEEEE?TT??EEEEEE??STT?---------SS?EEEEEE---??BTTS??-?EEEEEEEES---TT??SSS????EEE???TTTTTS--?EEEEEEEE--?SS-----SE--EEEEEEESSSSEEEEEEEE-E?T---------------TT??EE??GGGEEEEE?SSS?SS--SSS????EE?---------SSSSEEEEEEE?SSS----?EEEEEEESS??T-------------------T???EES??SSS?E-------EEEEEE?SSEEEEEES?GGG?----TT?BEEEEEESS------?TT?E--EESSSSS?TTTE---EEEEEEE?TT-SSEEEEEEEEESS?E 1R9N|A PF00931.17_NB-ARC_seed 12 360 !Q:0,0|16,18|21,21|28,29|43,45|53,53|56,56|65,66|69,72|86,86|89,91|93,116|119,121|126,126|139,139|142,142|150,151|154,155|158,164|168,168|171,171|179,179|186,187|189,190|196,197|200,201|213,217|221,221|223,234|238,238|251,251|263,264|267,267|270,270|272,272|280,280|284,288|291,293|296,297|312,312|314,314|325,331|333,334|337,338|350,351|354,354 Q:1,15|19,20|22,27|30,42|46,52|54,55|57,64|67,68|73,85|87,88|92,92|117,118|122,125|127,138|140,141|143,149|152,153|156,157|165,167|169,170|172,178|180,185|188,188|191,195|198,199|202,212|218,220|222,222|235,237|239,250|252,262|265,266|268,269|271,271|273,279|281,283|289,290|294,295|298,311|313,313|315,324|332,332|335,336|339,349|352,353|355,359 ?HHHHHHHHHHHTTST---TS?EEEEEE??TTSSHHHHHHHHH-??HHHHHHH?TT?EEEEEEES??HH----HHHHHHHHHHHHH?SS-??S?-----------------------SS???SHHH-HHHHHHHHHHHT?TT?EEEEEEE??HH--HH-------HTT?SS?EEEEEES?GGGGTT??S?-EEEEE??SS??HHHHHHHHHHH-----HTS?G------------GGS?THHHHHHHHHTT?HHHHHHHHHHH--HH-ST-T?HHHHHHH-HHS?????SS???SS??HHHHHHHHHHHHTS?T-TTHHHHHHGG-------G??TT??EEHHHHHHHHT??HH-HHHHH 1VT4|I PF00932.14_LTD_seed 51 170 !Q:0,1|18,18|22,34|42,42|45,45|47,47|50,50|53,53|60,62|71,72|75,75|78,85|88,88|99,108|119,126|129,142|144,144|151,151|154,155|157,157|167,169 Q:2,17|19,21|35,41|43,44|46,46|48,49|51,52|54,59|63,70|73,74|76,77|86,87|89,98|109,118|127,128|143,143|145,150|152,153|156,156|158,166 ??EEEEEEESSSEEEEEE?TTS-------------SEEEEEE?SS-S?EE?TT?EEEEEE---TTEEEEEE??TT?EE?-------TT?EEEEEETTSS-------???BTTTEEEETT?---????SS--------------S?EEEEEE?TT--S?EEEEEEEEE??? 3GEF|A PF00933.16_Glyco_hydro_3_seed 39 447 !Q:0,0|11,11|13,13|17,18|21,25|28,28|31,32|34,35|46,47|52,53|56,64|66,66|83,83|86,89|91,92|96,100|105,107|111,124|126,126|132,133|136,137|140,143|159,164|167,168|171,173|175,181|184,184|193,193|198,198|214,217|219,226|228,232|241,242|244,244|246,246|249,249|253,271|273,274|276,279|296,296|300,301|306,308|310,310|314,316|320,320|325,325|329,330|334,334|347,356|361,361|363,363|365,365|375,379|392,392|398,402|410,412|429,430|432,432|447,447 Q:1,10|12,12|14,16|19,20|26,27|29,30|33,33|36,45|48,51|54,55|65,65|67,82|84,85|90,90|93,95|101,104|108,110|125,125|127,131|134,135|138,139|144,158|165,166|169,170|174,174|182,183|185,192|194,197|199,213|218,218|227,227|233,240|243,243|245,245|247,248|250,252|272,272|275,275|280,295|297,299|302,305|309,309|311,313|317,319|321,324|326,328|331,333|335,346|357,360|362,362|364,364|366,374|380,391|393,397|403,409|413,428|431,431|433,446 ?HHHHHHHTEE?B?SEE??TT?----SS?EE??S??HHHHHHHHHH??SEEE??GG---------G?SSHHHHHHHHHHHHHH?SS----S??EEE-????BTTB???SSS-----------???S?HHHHH--HH??HH----HHHHHHHHHHHHHHH------HT??EE???B??-????TT?SSSGGGSS?SSHH-HHHHHHHHHHHHHHT----T--------T----?EEEEEEET??T-T?SS?TTT-------------------S??B????HHHHHHTTTHHHHHHH-HTT??EEEE???B?TTT???EEE?TTTS?EEE??GGG?HHHHIIIIIIIS?-----?--?SEEE?S?T-TSHHHHTTS?----HHHHHHHHHHHT?SBEES?????SGGGTHH---HHHHHHHHHHHHHHTS--S?HHHHHHHHHHHHHH- 1X38|A PF00934.15_PE_seed 135 98 !Q:0,8|36,36|39,42|73,73|86,97 Q:9,35|37,38|43,72|74,85 ????-????HHHHHHHHHHHHHHHHHHHHHHHHHHH-HT????SSSSHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHHHTT????????-??? 2G38|A PF00935.14_Ribosomal_L44_seed 44 88 !Q:1,3|6,12|14,15|17,17|28,31|35,35|41,42|44,47|49,62|68,80|82,87 Q:0,0|4,5|13,13|16,16|18,27|32,34|36,40|43,43|48,48|63,67|81,81 S???EE?????-?S??S?SSTTTTTTTS--??SSS?TTSSS??S????S------????????EETTT????????--???S?????? 1S1I|Z PF00936.14_BMC_seed 128 111 !Q:0,0|8,8|27,27|35,35|37,38|40,40|42,51|56,56|61,62|80,80|83,89|97,100|102,105|107,108|110,110 Q:1,7|9,26|28,34|36,36|39,39|41,41|52,55|57,60|63,79|81,82|90,96|101,101|106,106|109,109 ?EEEEEEE-ESHHHHHHHHHHHHHHSS?EEEEEEE?S--T-T----------EEEE-EEEE-?HHHHHHHHHHHHHHHHH-HS-------EEEEEEE----E----S--S? 3CGI|A PF00937.13_Corona_nucleoca_seed 21 500 !Q:2,3|6,34|37,38|40,70|72,72|74,74|76,76|78,78|81,81|86,86|90,95|98,99|101,103|107,107|110,111|119,125|129,135|147,149|151,151|154,163|170,171|174,182|184,186|190,200|203,205|211,367|369,499 Q:0,1|4,5|35,36|39,39|71,71|73,73|75,75|77,77|79,80|82,85|87,89|96,97|100,100|104,106|108,109|112,118|126,128|136,146|150,150|152,153|164,169|172,173|183,183|187,189|201,202|206,210|368,368 SS??SS??---------------------------SS??S???---------???---------------?S?S-S?S?SS?EEEE?SSS???-??TT??S???SSS?SS??EEEEEEE??-????TTT???????EEEEEEESSSS???S?SS?-------??SSEEEE??SS?????????S???TTT--?????????SS???STTEE???-----------------------??---------------------------------------------------------------------------------------------------------------------------------S------------------------------------------------------------?---------------------------------------------------------------------? 3HD4|A PF00939.14_Na_sulph_symp_seed 11 596 !Q:0,5|25,26|28,28|46,46|49,49|57,57|69,87|97,97|131,131|143,143|153,153|162,165|174,186|188,190|193,228|254,254|266,276|284,287|308,334|342,352|366,372|379,383|388,388|404,424|427,427|430,430|433,434|452,453|476,478|493,493|501,501|522,522|524,526|540,543|547,547|556,556|560,561|586,590|595,595 Q:6,24|27,27|29,45|47,48|50,56|58,68|88,96|98,130|132,142|144,152|154,161|166,173|187,187|191,192|229,253|255,265|277,283|288,307|335,341|353,365|373,378|384,387|389,403|425,426|428,429|431,432|435,451|454,475|479,492|494,500|502,521|523,523|527,539|544,546|548,555|557,559|562,585|591,594 ??????HHHHHHHHHHHHHHHHHHH??S?HHHHHHHHHHHHHHHHH?SS?HHHHHHH-HHHHTTTTSSS?------------------HHHHHTTTT?HHHHHHHHHHHHHHHHHHTTHHHHHHHHHSTTS?STHHHHHHHHH-HHHHHHTTS?HHHHHHHH----HHHHHHHS?------------S???SS?-----------------------------------TTTTTTTHHHHHHHHHHHTSSSSSS?HHHHHHHHHHT---------??HHHHHHH----HHHHHHHHHHHHHHHHHHHS????????--------???????????STHHHHH-----------HHHHHHHHHHHHH-------HHHHHH?--??SSHH-HHHHHHHHHHHHHTT---------------------SS?HH-HH--HHHSHHHHHHHHHHHHH--HHHHHHTTHHHHHHHHHHHHHH---TTTTHHHHHHHHTT-SSSSSSS?THHHHHHHHHHHHHHHHHHT-T-??THHHHHHHHHHHH??-?SSS?SSHHHHHT?SSS??TTTHHHHHHHHHHHHHHHHHHHHH-----HHTT? 4F35|A PF00940.14_RNA_pol_seed 94 1050 !Q:0,0|3,4|21,24|26,27|31,31|33,41|50,51|54,55|57,74|82,89|91,172|177,188|193,198|216,219|221,225|231,232|235,240|243,244|249,250|264,264|273,273|275,279|281,282|284,290|305,309|312,360|365,365|372,373|376,384|398,399|415,415|417,419|422,552|575,575|595,595|598,648|652,652|656,656|660,662|664,705|707,707|713,729|751,752|757,763|766,768|780,790|796,796|812,814|829,874|884,1003|1011,1022|1024,1026|1029,1039|1044,1044|1048,1049 Q:1,2|5,20|25,25|28,30|32,32|42,49|52,53|56,56|75,81|90,90|173,176|189,192|199,215|220,220|226,230|233,234|241,242|245,248|251,263|265,272|274,274|280,280|283,283|291,304|310,311|361,364|366,371|374,375|385,397|400,414|416,416|420,421|553,574|576,594|596,597|649,651|653,655|657,659|663,663|706,706|708,712|730,750|753,756|764,765|769,779|791,795|797,811|815,828|875,883|1004,1010|1023,1023|1027,1028|1040,1043|1045,1047 ?EE?-TTTHHHHHHHHHHHHH----S??TTS?H---------HHHHHHHH--HH--H------------------HHHHHHH--------H?---------------------------------------------------------------------------------TTTS---??-------GGGG------SSSHHHHHHHHHHHHHH----H-----TSSSG--GG?-----EE??EEEE??SSHHHHHHHHHTT?HHHHHHTT?S?---?S--S----???HHHHHHHHHHHHHH-----HH-------------------------------------------------HHTT?HHHHHT--TT?------??HHHHHHHHHHHHH??SSSHHHHHHHHHHHT?T---TS?----------------------------------------------------------------------------------------------------------------------------------TTTHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHHH-TT??------------------------------------------------?EEE?TTS?EEE???B---???????????----???????????????---------B?HHHHH-----------------HHHHHHHHHHHHHHHHHHHHH--HHHH-------TT???EEETTEEEEEG-----------GGHHH-HHHHHHHHHHHHHHS-?-HHHHHHHHHHHHHS??--------------------------------------------TTSHHHHHH------------------------------------------------------------------------------------------------------------------------HHHHHHS?????-------S-??GG-----------GGGG?TTS?? 1CEZ|A PF00941.16_FAD_binding_5_seed 94 253 !Q:0,2|6,7|19,23|35,35|47,49|53,53|56,56|59,60|64,65|70,71|73,76|85,85|93,102|109,109|111,111|122,122|129,129|136,180|183,184|187,187|198,198|208,209|212,215|222,222|226,230|237,239|242,242|251,252 Q:3,5|8,18|24,34|36,46|50,52|54,55|57,58|61,63|66,69|72,72|77,84|86,92|103,108|110,110|112,121|123,128|130,135|181,182|185,186|188,197|199,207|210,211|216,221|223,225|231,236|240,241|243,250 ???EEE??SSHHHHHHHHH-----HHGGGEEEESS?TTHHHHHHTTS???SEE-EE?TT?-GGG??EEEE--T----TEEEEETT?BHHHHHH?---------HHHHHH?H-HHHHHGGGSS?TTGGGT?BHHHHH---------------------------------------------HT??TT?SHHHHHHHTT?EEEEEETTE--EE----EEESTT-TEE-----ETTEES?-?TT?EEEEEEEE?? 3NVW|B PF00942.13_CBM_3_seed 29 96 !Q:6,9|14,14|16,16|24,25|29,29|42,43|46,49|61,61|64,65|69,69|87,87|96,96 Q:0,5|10,13|15,15|17,23|26,28|30,41|44,45|50,60|62,63|66,68|70,86|88,95 EEEEES???-SEES?B?EEEEEEE-?SSS?EEGGGEEEEEEE??SS-???EEEEEEEEEEE?TT??EEE?GGGEEEEEEEEEEEETT-EEEEEEEE- 3ZU8|A PF00943.14_Alpha_E2_glycop_seed 23 427 !Q:0,2|7,7|12,13|19,19|25,27|43,44|48,48|60,62|73,73|81,81|95,97|107,108|118,120|122,125|130,131|134,135|138,138|143,147|152,152|154,157|160,160|162,162|167,172|175,175|189,191|205,208|212,212|214,215|221,221|223,223|233,234|237,237|240,241|245,248|251,253|259,259|262,262|271,276|290,291|294,294|305,308|314,314|316,316|323,324|327,327|336,337|343,346|349,353|367,367|405,406|410,411|413,418|425,426 Q:3,6|8,11|14,18|20,24|28,42|45,47|49,59|63,72|74,80|82,94|98,106|109,117|121,121|126,129|132,133|136,137|139,142|148,151|153,153|158,159|161,161|163,166|173,174|176,188|192,204|209,211|213,213|216,220|222,222|224,232|235,236|238,239|242,244|249,250|254,258|260,261|263,270|277,289|292,293|295,304|309,313|315,315|317,322|325,326|328,335|338,342|347,348|354,366|368,404|407,409|412,412|419,424 ???EEES?SSSS-?EEETT?EEEEE???TTSEEEEEEEEEEEE?-TTS?EEEEEEEEEET---TEEEEEESTT?EEESSSB?EEEEEEEEEEEEE???BSSEEEEEE-?SSSEEEEEE???B????SSSB??SS??SS?EEEE-----EEEE?S????SS?E-EEEE--????EE?GGGEEESSSSEEE???TTSEEEEEESSSS????EES-S??EEESS?S?GGGEEEEEE??SS?EE??TTS??-?SS???EEEEE?SS?EEEEEEEE??????EEEEETTEEEEEE??SS?EEEEEEESSS????EEEEE?S?EEEEEE??TT?EEEEETTS??EEEEE?-??SS?????SSSTHHHHTTTSS?SSTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS??TTS??H------HHHHHH?? 3J0F|I PF00944.14_Peptidase_S3_seed 5 159 !Q:0,3|5,6|8,8|14,14|23,25|29,32|39,39|41,41|49,50|59,63|71,71|73,74|76,78|80,82|88,89|103,104|107,107|110,110|114,114|117,117|129,129|140,140|144,150|153,153|155,158 Q:4,4|7,7|9,13|15,22|26,28|33,38|40,40|42,48|51,58|64,70|72,72|75,75|79,79|83,87|90,102|105,106|108,109|111,113|115,116|118,128|130,139|141,143|151,152|154,154 ????S??S?EEEEE-TTEEEEEE???SSS????SSSSSS?S?HHHHHHH??EETTTTEE?????HHHHHTS?B??S???S???BSSSS??EEETTEEEEETTS??SS?TT?EEE?SS?BEEEEEEEEEE?SSEEEEEEEE?SSS???????SS?B??-- 4AUS|A PF00945.13_Rhabdo_ncap_seed 11 425 !Q:0,0|4,6|8,23|25,26|29,39|53,55|57,57|69,70|72,74|76,79|82,84|87,87|89,89|91,91|95,115|117,121|123,125|145,146|171,173|175,175|185,187|189,192|210,212|229,229|244,247|249,249|254,255|267,269|273,273|290,290|293,293|316,316|324,325|329,329|348,354|366,396|411,412 Q:1,3|7,7|24,24|27,28|40,52|56,56|58,68|71,71|75,75|80,81|85,86|88,88|90,90|92,94|116,116|122,122|126,144|147,170|174,174|176,184|188,188|193,209|213,228|230,243|248,248|250,253|256,266|270,272|274,289|291,292|294,315|317,323|326,328|330,347|355,365|397,410|413,424 ?SSS???B????????????????S??EE????????---STHHHHHTTTTTT???S?HHHHHHHHHHH??B???S????SS???SS?B?S?SEE?????????????????????S?????S???HHHHHHHHHHHHHHHHHHH??SSTHHHHHHHHHHHHHHHTTTSSS???S?TTTTTTTTT???S????HHHHHHHHHHHHHHHHS?-?SSGGGGGTTGGGSSTT?HHHHHHHHHHHSSS??-?S?GGGG??STTHHHHHHHH??-SSS?SSSTTSGGGTHHHHSS?SS?TTSTTTTHHHHHHHHHHHHHTT?HHHHTSB??SSS?HHHHHHHHHHHHHHHTTB???????BSSHHHHHHHH???????????????????????????????HHHHHHHHHTTTTB??HHHHHHHHHHHH 3PU4|A PF00947.14_Pico_P2A_seed 9 127 !Q:4,5|26,26|29,33|36,39|50,50|57,57|59,60|66,66|72,72|84,84|88,91|97,97|109,109|121,122|126,126 Q:0,3|6,25|27,28|34,35|40,49|51,56|58,58|61,65|67,71|73,83|85,87|92,96|98,108|110,120|123,125 EGGG??HHHHHTEEEEETTTTEEEEE?SS?????BB????SEEEEEBTTT?SEEEEE?B??SEEEE?SBTTB?SEEEESEEEEE?SSS????BSEEE?SSSEEEEEEEE?SSEEEEEESTT??TTS? 1Z8R|A PF00949.16_Peptidase_S7_seed 50 180 !Q:0,4|9,10|15,16|19,21|24,30|44,44|51,52|56,58|64,64|70,73|85,92|95,96|102,103|107,108|114,115|120,120|123,124|130,134|137,137|140,140|144,147|151,151|157,158|162,162|164,168|171,171|176,176|178,179 Q:5,8|11,14|17,18|22,23|31,43|45,50|53,55|59,63|65,69|74,84|93,94|97,101|104,106|109,113|116,119|121,122|125,129|135,136|138,139|141,143|148,150|152,156|159,161|163,163|169,170|172,175|177,177 ??-??SEEE--EEEE??SS-??EE-------EEEEEEETTEEEE?HHHHTT??EEE---TTEEE?EEEEE----TTTTEEEESSS????????TT??EEEEE??TTS??EEEEE??EEEE?SS?-EEEEE?????TT?TT?EEE---?TTS?EEEES??EEE?T-----TS?EEEE?B?? 2GGV|B PF00952.12_Bunya_nucleocap_seed 17 229 !Q:0,5|8,8|11,12|28,29|50,52|55,55|66,66|68,69|78,80|84,84|103,103|105,106|117,119|126,128|167,168|178,179|183,183|186,186|189,189|200,201|207,212|215,217|220,220|222,228 Q:6,7|9,10|13,27|30,49|53,54|56,65|67,67|70,77|81,83|85,102|104,104|107,116|120,125|129,166|169,177|180,182|184,185|187,188|190,199|202,206|213,214|218,219|221,221 ??????SS?SS??SHHHHHHHHHHHGGG??HHHHHHHHHHHHHHHHHHHH???SS?EEEETTEEEE?B??SSTTTSSS???SSS?BHHHHHHHHHHHHHHHHT-T?-STTHHHHHHS???HHHHTT???GGGHHHHHHHTSTTGGGGGGGGTTHHHHHHHHTTTSSS??THHHHTTSS??SSS?SS?SS?SSTTTTTTTT??HHHHS??????SS???SS?S??????? 4J1J|A PF00953.16_Glycos_transf_4_seed 116 338 !Q:5,8|13,15|30,35|40,46|48,48|69,98|102,105|109,118|121,121|123,123|125,157|161,161|163,163|168,172|175,178|188,192|204,212|220,220|236,240|247,250|252,254|263,266|269,275|280,280|283,283|286,289|295,295|299,303|305,307|309,311|323,324|327,330 Q:0,4|9,12|16,29|36,39|47,47|49,68|99,101|106,108|119,120|122,122|124,124|158,160|162,162|164,167|173,174|179,187|193,203|213,219|221,235|241,246|251,251|255,262|267,268|276,279|281,282|284,285|290,294|296,298|304,304|308,308|312,322|325,326|331,337 HHHHH----HHHH---HHHHHHHHHHHHHH------HTSS------?S?HHHHHHHHHHHHHHHHHHHH------------------------------TTS????EEE?---------SS?T-T--------------------------------?EEE?G-GGHH-----HH----HHHHHHHHH-----HHHHHHHHHHS??-------HHHHHHH-HHHHHHHHHHHTSHH-----HHHHHT????T---TTTHHHHH----HH-------HHHH-HH-HH----HHHHH-TTT-----T---B???HHHHHHHHHHH--HH----HHHHHTT 4J72|A PF00956.13_NAP_seed 97 440 !Q:1,2|6,6|31,31|46,48|58,63|66,68|80,123|126,126|130,131|134,146|149,150|152,152|160,160|168,169|172,174|182,182|190,191|193,194|196,207|210,210|219,219|222,222|224,224|228,229|231,232|243,247|249,250|253,258|261,262|264,268|271,272|277,280|283,283|287,287|295,330|336,349|356,362|364,370|372,397|409,410 Q:0,0|3,5|7,30|32,45|49,57|64,65|69,79|124,125|127,129|132,133|147,148|151,151|153,159|161,167|170,171|175,181|183,189|192,192|195,195|208,209|211,218|220,221|223,223|225,227|230,230|233,242|248,248|251,252|259,260|263,263|269,270|273,276|281,282|284,286|288,294|331,335|350,355|363,363|371,371|398,408|411,439 H--HHH-HHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHH---HHHHHHTSS---???HH---HHHHHHHHHHH--------------------------------------------TT?GGG??SS?????????????SS-?T-THHHHHH-HTSTTGG--GT??-HHHHTGG-GGEEEEE??B??S------------SS?EEEEEEEE?TT-T?SSB??S--EEEEEEEEES-----S??SS------SS-?E-----EE--EEEE????BS?TTT?TTEEEEE?--------------------????????--?????EEEEE??-----------?GGGGGS------?S------?S???-----------------------TTSSSTTHHHH--HHHHHHHHHHHHHHHTTTTTHHHHHHSHH 2ZD7|A PF00957.16_Synaptobrevin_seed 111 94 !Q:1,1|24,24|28,31|34,37|39,40|42,44|63,63|67,70|93,93 Q:0,0|2,23|25,27|32,33|38,38|41,41|45,62|64,66|71,92 S?SHHHHSSHHHHHHHHHHHHHHH-HHH????SS????S??S???SSSHHHHHHHHHHHHHHS?HHH----HHHHHHHHHHHHHHHHHHHHHH? 3B5N|A PF00958.17_GMP_synt_C_seed 161 231 !Q:7,13|21,21|26,26|53,55|80,80|83,84|87,88|91,93|95,95|97,107|130,130|134,134|137,138|144,149|154,158|164,165|168,168|176,178|180,180|184,184|186,195|208,208|220,222|227,227|230,230 Q:0,6|14,20|22,25|27,52|56,79|81,82|85,86|89,90|94,94|96,96|108,129|131,133|135,136|139,143|150,153|159,163|166,167|169,175|179,179|181,183|185,185|196,207|209,219|223,226|228,229 HHHHHHH-------HHHHHHS?EEEE-EEEEEEEEEETTEEEEEEEEEEEESS???HHHHHHHHHHHHHHBTTEEEEEEE?SS??SS??SS???B?S?----------HHHHHHHHHHHHHHHHHHHHTT?GGG?SB??EEEES??????GGGT?????EEEEE??BB?SSSSSBB???B-TTT-B?---------HHHHHHHHHHHH-HSTTEEEEEEE???BTTS?SS? 2VXO|A PF00959.14_Phage_lysozyme_seed 18 160 !Q:0,0|7,12|14,14|17,18|21,42|56,56|67,67|69,77|81,81|96,96|114,114|124,124|135,136|141,147|150,150 Q:1,6|13,13|15,16|19,20|43,55|57,66|68,68|78,80|82,95|97,113|115,123|125,134|137,140|148,149|151,159 ?EEEETT------B?SS??TT??------------------??HHHHHHHHHHHHH-HHHHHHHHHS?G---------GGS?HHHHHHHHHHHHHH?HHHHHEEEETTTTEEEE?HHHHHHHTT?HHHHHTTGGG??EETT-------EE?HHHHHHHHH 4EJ4|A PF00960.13_Neocarzinostat_seed 4 113 !Q:1,3|5,6|8,10|22,23|26,26|44,44|48,48|53,54|57,58|66,66|76,76|89,91|98,98|102,103|105,105|109,109|111,112 Q:0,0|4,4|7,7|11,21|24,25|27,43|45,47|49,52|55,56|59,65|67,75|77,88|92,97|99,101|104,104|106,108|110,110 B???B??B???TTEEEEEEEBS??TT?EEEEEEEEEEETTEEEE?TTS?EEEE??SS??EEEEEEE?SEEEEEETT-SSEEEEEETTTS--?EEEEEE?SSS??S?EEE?B?? 1O5P|A PF00961.14_LAGLIDADG_1_seed 91 167 !Q:17,17|19,33|40,60|70,75|91,112|130,132|148,152 Q:0,16|18,18|34,39|61,69|76,90|113,129|133,147|153,166 HHHHHHHHEEEEEEEEE?S---------------SSSSEE---------------------EEEEEEEEE?-----GGGHHHHHHHHHHHT--------------------??EEEEEEETTEEEEEEEE??-HHHHHHTHHHHHHHS?--??STHHHHHHHHHHHH 2FLD|A PF00962.17_A_deaminase_seed 15 470 !Q:2,2|13,13|15,15|30,31|33,35|44,44|55,55|59,60|64,67|69,69|72,76|84,85|88,89|97,97|132,133|152,154|165,166|176,176|194,203|206,206|228,228|232,240|243,250|254,255|259,264|272,273|283,298|306,309|312,315|320,320|331,337|340,340|342,343|349,349|360,370|372,373|377,377|385,386|388,389|393,393|403,404|408,409|411,411|416,417|434,436|438,439|441,442|457,459|468,468 Q:0,1|3,12|14,14|16,29|32,32|36,43|45,54|56,58|61,63|68,68|70,71|77,83|86,87|90,96|98,131|134,151|155,164|167,175|177,193|204,205|207,227|229,231|241,242|251,253|256,258|265,271|274,282|299,305|310,311|316,319|321,330|338,339|341,341|344,348|350,359|371,371|374,376|378,384|387,387|390,392|394,402|405,407|410,410|412,415|418,433|437,437|440,440|443,456|460,467|469,469 TS?EEEEEEETTT?S?HHHHHHHHHHHHHT??S???EEETTEEE?HHHHHHHHSS?STT??STT????S?SS?????SSSHHHH??SS??HHHHHHS?SSSTTTTTTHHHHHHHHHHHHTTSSSEEEEEEEE??SSSSTHHHHHHHHHHTTT???SSEEEEEEEE??HHHHTTSSS?SSTHHHHHHHSSHHHHH----------HH?GGGSTTTHHHHTTEEEEEEES?TTS---??????SS???-----TTT??SSS---???HHHHHHH--HHHHHHHHH----------------HHHTTTT????EE????SSSS?THHHHHHHHH------?SS?S??GGGGG?HHHHHHHHHH-----------T??EEE?HHHHTTT--T??STT?SHHHHHHTT??EEE??B?HHHH??SSSHHHHHHHHHHHHH---T??H--HHHHHHHHHHHHHS???HHHHHHHS?T 3EWD|A PF00963.13_Cohesin_seed 40 174 !Q:5,5|10,11|14,14|26,26|31,31|41,42|54,54|56,69|71,71|73,74|84,85|95,96|99,99|102,103|109,109|111,112|123,125|128,128|131,142|155,155|159,159|161,161|163,163|168,168 Q:0,4|6,9|12,13|15,25|27,30|32,40|43,53|55,55|70,70|72,72|75,83|86,94|97,98|100,101|104,108|110,110|113,122|126,127|129,130|143,154|156,158|160,160|162,162|164,167|169,173 EEEEE?EEEE-?TT?EEEEEEEEEST-GGGT?BSEEEEEEE??TTTEEEEEEEE?T--------------T?S--SHHHHEEEE--EETTEEEEE--EE?SS-?GGGSB?S?-EEEEEEEEEE???SS?EE------------EEEEEEEEEEEE?TTS?B?S?EEEE?EEEEE 2ZF9|A PF00964.12_Elicitin_seed 87 112 !Q:0,0|2,3|24,26|31,35|39,39|41,43|47,47|50,52|62,62|76,79|81,82|86,88|90,90|94,95 Q:1,1|4,23|27,30|36,38|40,40|44,46|48,49|53,61|63,75|80,80|83,85|89,89|91,93|96,111 ?B??HHHHHHHHHHHGGGGGSHHH---HHHH-----HHH-S-??TTT?SS???HHHHHHHHH?HHHHHHHHHHHHT??-?S--SEE---E?TTT??EEEHHHHHHHHHHHHH 1LRI|A PF00965.12_TIMP_seed 25 238 !Q:0,10|18,18|21,31|34,34|36,36|38,41|45,51|57,64|70,73|78,78|81,88|93,93|95,95|99,110|112,117|121,123|125,130|140,143|147,149|155,155|172,172|174,175|177,183|185,186|191,199|203,204|207,207|210,210|213,213|224,227|230,230|234,234|237,237 Q:11,17|19,20|32,33|35,35|37,37|42,44|52,56|65,69|74,77|79,80|89,92|94,94|96,98|111,111|118,120|124,124|131,139|144,146|150,154|156,171|173,173|176,176|184,184|187,190|200,202|205,206|208,209|211,212|214,223|228,229|231,233|235,236 --????-?-??HHHHHHH?SE-----------EE?B?E----EEE???????BTTBS?----???EEEEE????EEES?SS-----???EEEE?S?HHH------------H???-??BSS???B????--EEETTTEEE?--?TTS???BTTTS?HHHHHIIIIIGGGSTT-S??E-------E??SSSB?------??STT??EE?HH-HH?SSSSSHHHHT???-EE?TTS?EE? 1OO9|B PF00967.12_Barwin_seed 8 131 !Q:8,8|11,13|19,19|26,27|32,33|39,39|47,48|52,52|56,59|65,65|86,88|92,96|100,100|109,111|129,130 Q:0,7|9,10|14,18|20,25|28,31|34,38|40,46|49,51|53,55|60,64|66,85|89,91|97,99|101,108|112,128 EEEEEEEE?EE???GGGTT?TTSTTT??TTHH--HHTTS?THHHHHS??EEE?SSS????GGGTT?EEEEEETTTTEEEEEEEEEE--?SSS----?EES?SSSSHHHH??-SSHHHHHTEEEEEEEEE?? 1BW4|A PF00969.14_MHC_II_beta_seed 121 84 !Q:5,5|26,28|36,36|46,50|60,60 Q:0,4|6,25|29,35|37,45|51,59|61,83 EEEEE-ETTTTEEEEEEEEEETTEEE---EEEETTT?SEEESSGGG-----HHHHHHHHH?HHHHHHHHHHHHHTHHHHHHHHG 4GBX|D PF00970.19_FAD_binding_6_seed 115 133 !Q:19,19|21,23|25,26|29,39|42,42|48,48|50,52|55,55|59,60|64,66|68,68|70,71|73,75|79,80|87,89|93,93|96,96|99,100|105,105|108,108|111,114|117,117|119,119|127,127|129,132 Q:0,18|20,20|24,24|27,28|40,41|43,47|49,49|53,54|56,58|61,63|67,67|69,69|72,72|76,78|81,86|90,92|94,95|97,98|101,104|106,107|109,110|115,116|118,118|120,126|128,128 EEEEEEEEEEETTEEEEEE-E?--S-?TT??---???--?TT?EEEEE?E---ET-TEE??EEE???S?T--T--?SSE--EEEEEE???BSS?SS?TB??TTHH-HH-TT-?-?TT?E-EEEEEEE?S-??? 1IB0|A PF00972.15_Flavi_NS5_seed 7 660 !Q:3,14|16,24|39,39|42,42|44,45|48,50|62,69|72,72|79,79|85,85|94,94|96,96|111,117|137,137|140,146|155,155|158,162|168,170|179,179|197,198|201,202|208,210|214,214|219,220|222,223|228,229|258,258|261,262|280,280|283,285|293,294|308,311|337,337|341,343|355,356|359,359|385,386|392,394|426,427|435,436|444,445|450,450|454,456|464,465|476,476|480,480|487,488|504,505|524,524|542,542|545,548|550,550|552,554|557,559|566,566|579,579|582,589|595,598|607,608|611,611|633,633|636,645|653,659 Q:0,2|15,15|25,38|40,41|43,43|46,47|51,61|70,71|73,78|80,84|86,93|95,95|97,110|118,136|138,139|147,154|156,157|163,167|171,178|180,196|199,200|203,207|211,213|215,218|221,221|224,227|230,257|259,260|263,279|281,282|286,292|295,307|312,336|338,340|344,354|357,358|360,384|387,391|395,425|428,434|437,443|446,449|451,453|457,463|466,475|477,479|481,486|489,503|506,523|525,541|543,544|549,549|551,551|555,556|560,565|567,578|580,581|590,594|599,606|609,610|612,632|634,635|646,652 EEE????????????S?????-???GGGHHHHHHHHHHT?TT?B??TT???SSSEEEEEEEE????????EE?HHHHHT?GGGGG?HHHHTEEE?B?SHHHHHHHHHHHTS???????HHHHHHHHHHHHHHHHHHT-TT???????HHHHHHHS?TT?????SSGGG???SSHHHHHT?HHHHHHHHHHHHHHHTT??SS??EEEEE???EEE?BTTB??B??EEEE??HHHHHHHHHHHTHHHHTTTTSHHHHSSB?TT??HHHHHHHHHHHHTSSSS?EE???BTTGGGG??HHHHHHHGGGGGG?--?HHHHHHHHHHHHHTTTSEEEEEEEE?GGG?--EEEEEEEESSS??TT?TTHHHHHHHHHHHHHHHHHHHHTTS??GGGSS???HHHHHHHHHHHHHHHHHHHTTEEEETTEEEE??SSSSGGG??HHHHHTT??BSSS?TTS???EESSGGG??BTTBEEEEEE?TTS?EEEEEE??HHHHHHHHTEESSTT??HHHHHHHHHHHHHHHHHH?TTSHHHHHHHHHHHHHS?TT????S?S???TT???TTSSSS?HHHHHHHHHTTT?TT????????SGGGS????HHHHHHTT??TT?HHHHHHHHTHHHHHHHHHHHH?SS?-----????GGGSGGG??????? 1R6A|A PF00974.13_Rhabdo_glycop_seed 8 546 !Q:0,15|17,18|25,25|28,30|32,32|34,35|38,46|53,53|55,56|62,63|65,66|71,71|74,74|81,84|94,94|98,98|103,106|113,115|130,138|140,144|149,149|163,164|168,168|172,173|176,176|185,185|189,193|201,201|206,212|217,220|230,231|237,237|240,240|251,251|255,255|268,268|272,272|278,278|280,283|291,292|294,295|298,306|312,312|317,317|322,322|340,340|343,343|352,353|382,383|391,391|397,400|402,406|415,415|419,419|424,424|429,429|434,434|439,440|445,446|449,449|451,452|460,545 Q:16,16|19,24|26,27|31,31|33,33|36,37|47,52|54,54|57,61|64,64|67,70|72,73|75,80|85,93|95,97|99,102|107,112|116,129|139,139|145,148|150,162|165,167|169,171|174,175|177,184|186,188|194,200|202,205|213,216|221,229|232,236|238,239|241,250|252,254|256,267|269,271|273,277|279,279|284,290|293,293|296,297|307,311|313,316|318,321|323,339|341,342|344,351|354,381|384,390|392,396|401,401|407,414|416,418|420,423|425,428|430,433|435,438|441,444|447,448|450,450|453,459 ---------------?E--EEEEES?SS???E-E??TT?????????TTTTTT?B??EEEEE--E??TTTT?EE?EEEEEE----EEEEEEEEE?TTS?EEEE----EEEEEE???HHHHHHHHHHHHTT---??????S?????BTTB-EEEEEEEEEEEEE??EEE?TTT??EE?TTBGGGEE?SSE-----EEBSSTT?EEEE???-???SSSS--??EEEEEEBSS??GGGTT?SS?EEEETTEEEE?TTS?EEEEETTEEEEE?TTS?EEEES?H----HHHHHHT??B??TT---??????BSSSS?GGGS?HHHH-HHHHHHHHHHHHHHHSS?EE?HHHHHTTS??SSEEEEEEEEETTEEEEEEEEEEEEEES?-SEESSSB?EETTS????B?????EEETTEEE?GGG?EEET-TEEE?HHHH?SSSS??TTSS??EE?B??SSGGGGT????????-------------------------------------------------------------------------?---? 2J6J|A PF00975.15_Thioesterase_seed 38 314 !Q:0,1|6,7|10,12|23,23|26,27|32,34|38,38|41,51|67,67|70,75|98,105|112,112|115,135|138,139|153,155|159,159|168,172|189,203|207,207|215,226|240,243|245,245|247,247|249,249|256,266|276,276|278,278|281,282|289,289|296,296|300,301|313,313 Q:2,5|8,9|13,22|24,25|28,31|35,37|39,40|52,66|68,69|76,97|106,111|113,114|136,137|140,152|156,158|160,167|173,188|204,206|208,214|227,239|244,244|246,246|248,248|250,255|267,275|277,277|279,280|283,288|290,295|297,299|302,312 ??EEEE??TT?-?SGGGHHHHHH?SS?-EEEE???TTS?TT----------?HHHHHHHHHHHHTTT?SS?---??EEEEETHHHHHHHHHHHHHHHH????????EEEEES?SS???-?????????????????HH--HHHHHHHHHHHHS???HHH-HHHHHTTS?----SHHHHHHHHHHHHHHH--------------?TTS?HHHHHHH------------HHHHHHHHHHHHT????S?B?S?EEEEEE???????????TTTTTTTTB?S?EE--EEEESS?TTGGGS-HHH--HHHHHHHHHHH? 2PX6|A PF00977.16_His_biosynth_seed 146 339 !Q:8,11|15,15|17,17|20,22|24,38|43,43|47,49|55,56|58,59|63,63|71,71|73,73|76,78|86,87|92,94|96,98|100,101|105,109|111,111|118,123|132,133|136,136|139,143|145,148|156,159|162,162|164,165|169,170|179,180|190,191|196,205|207,217|231,234|251,253|267,267|269,274|276,276|279,279|287,288|290,290|292,293|299,301|311,314|319,322|331,332|337,338 Q:0,7|12,14|16,16|18,19|23,23|39,42|44,46|50,54|57,57|60,62|64,70|72,72|74,75|79,85|88,91|95,95|99,99|102,104|110,110|112,117|124,131|134,135|137,138|144,144|149,155|160,161|163,163|166,168|171,178|181,189|192,195|206,206|218,230|235,250|254,266|268,268|275,275|277,278|280,286|289,289|291,291|294,298|302,310|315,318|323,330|333,336 EEEEEEEE----ETT-E-EE---E???--------????EEEE?HHH---HHHHH--H--HTT?SSEEEEE?S?SH---HHHHHHH--HHHH---H---H--HTT??---S?EEEESS----??SHHHHHHH--HH-TT----?S----EEEESHH----HH-H?-THH--HHHHHHHH-?GGGEEEEEE--EEEE----------T-----------TEEEEEETTTTEE----EEEEHHHHHHHHHHTT--?SEEEEEETTTTTS?S???---H-HH-HHHHHHH?-S-S?-EEEES???SHHHHHHHH----TSTT?--?EEEESHHH--HHSS?? 1VZW|A PF00979.12_Reovirus_cap_seed 5 390 !Q:0,6|21,23|32,33|36,39|58,59|66,67|69,79|91,92|117,117|128,129|134,135|147,147|150,154|158,162|185,188|196,196|205,205|207,207|213,216|219,220|224,229|233,234|240,240|242,243|246,246|261,262|266,269|273,275|279,280|284,285|291,294|298,300|320,320|329,329|350,350|355,357|360,360|363,363|368,368|372,374|377,387|389,389 Q:7,20|24,31|34,35|40,57|60,65|68,68|80,90|93,116|118,127|130,133|136,146|148,149|155,157|163,184|189,195|197,204|206,206|208,212|217,218|221,223|230,232|235,239|241,241|244,245|247,260|263,265|270,272|276,278|281,283|286,290|295,297|301,319|321,328|330,349|351,354|358,359|361,362|364,367|369,371|375,376|388,388 ???????HHHHHHHHHHHTTT???EEBTTTBT??SS????SEEEETTEEEETTTTEEE--EEGGGT??S???????????HHHHHHHHHHH--HHHHHHHHHHHHHHHHHHHHHHTS?HHHHHHHHHH??EEEE??GGGSSTTSTTT?TT??---TTS?????TTHHHHHHHHHHHHHHHHHHTT---?EESSEES?THHHHTTS?B?GGGGG????SS??TTS??????EEE??HHHHH?G--GG?HHHHHHHTSTHHHH??GGG????EEE???STT??EEE??GGGTS??--EEE???HHHHHGGGHHHHHHHHHHS?HHHHHHHH?TTHHHHHHHHHHHHHHHHTS?GGGG???SS?SS?SSSS?EEE???EE-----------E? 1FN9|A PF00980.12_Rota_Capsid_VP6_seed 3 396 !Q:0,0|17,18|43,43|48,49|53,55|60,69|73,73|101,103|107,107|110,111|124,124|127,131|145,148|155,156|168,169|172,172|175,175|227,228|234,234|239,239|244,244|249,249|253,255|275,276|295,296|299,300|308,308|312,314|333,335|339,340|354,357|361,361|365,365|373,374|395,396 Q:1,16|19,42|44,47|50,52|56,59|70,72|74,100|104,106|108,109|112,123|125,126|132,144|149,154|157,167|170,171|173,174|176,226|229,233|235,238|240,243|245,248|250,252|256,274|277,294|297,298|301,307|309,311|315,332|336,338|341,353|358,360|362,364|366,372|375,394 ?HHHHHHHHHHHHHHHH??SEEEGGGTHHHHHHHHHHHHHHTT?EEEE??STT???EEEE??????????SEE?HHHHHHHHHHHHHHHHHHHHHHHHHTT???STT?SS??SHHHHHHTSGGG?TT?????SHHHHHHHHHHTT????EEEESB??EEEEEEEEEEE??TT?SS?EEEEEEEEETEEEEEEEETTTTTTSGGGEEEEEEEEEEEEEEEEEEEEEEE??GGGSS?EEEE?TTSS?EEEE?EEE???EEEEEEEEETTEEEEEEES??EEEEEEEEEEEEEEEEEE??SS??HHHHTTS?SSS???SEEEEEEEEEEEEEEESS???BSS??HHHHHHHHHHHTT????SSS?GGG?HHHHHHT??HHHHHHHHHHHHHHHHHTTT?- 4F5X|C PF00982.16_Glyco_transf_20_seed 23 575 !Q:0,1|6,6|9,11|13,23|27,31|33,34|36,36|38,39|51,56|58,58|60,61|72,72|76,81|86,95|101,110|117,123|134,139|152,152|155,161|163,166|188,192|195,195|216,223|225,225|230,231|233,236|245,246|281,299|308,310|323,328|338,338|340,342|355,355|363,364|366,366|370,370|379,379|386,386|399,400|402,402|409,409|429,429|433,434|436,436|442,442|444,447|458,458|464,465|470,471|482,482|484,497|500,501|515,515|519,519|523,523|526,526|540,541|560,560 Q:2,5|7,8|12,12|24,26|32,32|35,35|37,37|40,50|57,57|59,59|62,71|73,75|82,85|96,100|111,116|124,133|140,151|153,154|162,162|167,187|193,194|196,215|224,224|226,229|232,232|237,244|247,280|300,307|311,322|329,337|339,339|343,354|356,362|365,365|367,369|371,378|380,385|387,398|401,401|403,408|410,428|430,432|435,435|437,441|443,443|448,457|459,463|466,469|472,481|483,483|498,499|502,514|516,518|520,522|524,525|527,539|542,559|561,574 ??EEEE?SS???S-----------SGG-----G??S?H--HHHHHHHHHHH------H?E--EEEEEEEEES?TTS?----?EEEE----------ETTEE----------EEEEEE?------HHHHHHHTTT------HHHHTHHHHHTT?GG-------G????HHHHHHHHHHHHHHHHHHGGG??---TT?EEEEESGGGTTHHHHHHHTT??------S?EEEE??S????HHHHTTST--THHHHHHHHTTSSEEEESSHHHHHHHHHHHHHHS?------------------EEEEETTE---EEETTEEEEEEE??????HHHHHHHHH-S???HHHHHHHHHTTT-SEEEEEE??B?GGG?HHHHHHHH-HHHHHH?GGGTTTEEEEEE??B?STTSHH-HHHHHHHHHHHHHHHHHHH?BTT--B?SEEEE?S-???HHHHHHHHHH?SEEEE??SSBS??HHHHHHHHHS?T--------------TS??EEEEETTBGGGGT?TTS-EEE?TT?HHHHHHHHHHHHT??HHHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHT 3T7D|A PF00983.13_Tymo_coat_seed 9 176 !Q:0,21|39,39|41,42|49,49|74,74|81,81|90,90|93,96|103,104|108,108|116,116|119,119|122,122|127,128|133,134|141,142|144,146|153,155|158,161|164,164 Q:22,38|40,40|43,48|50,73|75,80|82,89|91,92|97,102|105,107|109,115|117,118|120,121|123,126|129,132|135,140|143,143|147,152|156,157|162,163|165,175 ??????????????????????SEEEEEEEEEEEEESSS?B??EEETTT?HHHHHHHTTEEEEEEEEEEEEEEE?GGGGTS?EEEEEEEE?SS????GGGGGG--BTT?EEEEESS?TT?SS?EEEE??GGGS??EEESSS??S???EEEEEB???SS??--SS?SEEEEEEEEEE 2FZ2|A PF00984.14_UDPG_MGDP_dh_seed 26 100 !Q:33,34|49,51|55,58|60,62|82,82 Q:0,32|35,48|52,54|59,59|63,81|83,99 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS??HHHHHHHHHTSTTT?--SSS????S???SSSHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHH 3PHL|A PF00986.16_DNA_gyraseB_C_seed 72 74 !Q:5,5|10,10|12,12|17,17|27,27|31,32|36,37|40,41|43,46|50,51|60,60|62,73 Q:0,4|6,9|11,11|13,16|18,26|28,30|33,35|38,39|42,42|47,49|52,59|61,61 HHTTT?EEEE?S?GGGS?HHHHHHHHT?TTT??EEE??HH--H----HHH--HHHHHHHH?S?-?????????? 3LTN|C PF00988.17_CPSase_sm_chain_seed 134 167 !Q:0,0|10,10|16,16|18,18|20,23|25,26|28,29|39,40|43,43|50,50|65,66|69,71|75,86|88,89|91,96|98,102|104,105|111,111|114,115|117,122|125,125|127,127|129,129|139,140|146,146|157,157|159,160 Q:1,9|11,15|17,17|19,19|24,24|27,27|30,38|41,42|44,49|51,64|67,68|72,74|87,87|90,90|97,97|103,103|106,110|112,113|116,116|123,124|126,126|128,128|130,138|141,145|147,156|158,158|161,166 ?EEEEEETTS?EEEEE-E?S?---S--E--EEEEEEEEE??SS?HHHHHT?GGGBTEEEEESSSB??TT???GGG-----------?S--S------S-----S??BSEEE?SB??S?--???TT?S-S?HHHHHHHTT??EEESS?HHHHHHHHHH-H??EEEEEE 1BXR|B PF00989.19_PAS_seed 49 134 !Q:0,14|21,22|31,31|39,41|43,44|57,57|63,67|80,82|87,88|94,98|100,100|104,104|122,124|133,133 Q:15,20|23,30|32,38|42,42|45,56|58,62|68,79|83,86|89,93|99,99|101,103|105,121|125,132 ?????????---???EEEEEE--TTSBEEEE?HHHHHHH???H--HHHTTSBGGGGS?TTHHH-----HHHHHHHHHHHH???SSBT??EEEEE-----E?TTS?EEEEEEEEEEEEETTEE---EEEEEEEE? 3GDI|A PF00990.16_GGDEF_seed 49 181 !Q:0,1|3,3|7,8|10,10|29,32|34,36|54,54|74,74|76,79|86,86|98,99|102,104|121,121|124,125|130,130|133,135|143,153|157,158|180,180 Q:2,2|4,6|9,9|11,28|33,33|37,53|55,73|75,75|80,85|87,97|100,101|105,120|122,123|126,129|131,132|136,142|154,156|159,179 ??B?TTT??B?HHHHHHHHHHHHHHHHTS----S???EEEEEEETTHHHHHHHS?HHHHHHHHHHHHHHHHHTS?T----TSEEEE?SSSEEEEEETT??HH---HHHHHHHHHHHHHHTS?EE?-GGGS?EE???EEEEEEE?---------?STT??HHHHHHHHHHHHHHHHHTTSS? 1W25|A PF00992.15_Troponin_seed 56 151 !Q:35,44|53,53|90,105|110,110|112,112|115,115|118,123|135,140|143,150 Q:0,34|45,52|54,89|106,109|111,111|113,114|116,117|124,134|141,142 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS????-???--SHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTT----------------GGGT?S?SS?SS??????HHHHHHHHHTT??????SS???????? 1YTZ|T PF00993.15_MHC_II_alpha_seed 51 85 !Q:49,49|51,55|80,84 Q:0,48|50,50|56,79 SEEEEEEEEEEEETTTEEEEEEEETTEEEEEEETTTTEEEESSHHHHHH?B??---THHHHHHHHHHHHHHHHHHHTTTS????? 4GBX|C PF00994.19_MoCF_biosynth_seed 149 278 !Q:5,5|10,10|13,20|22,24|27,27|29,38|40,41|52,53|55,59|63,63|70,70|73,73|84,89|96,98|105,113|118,130|133,133|139,145|150,150|156,156|158,206|208,208|210,212|217,219|223,230|232,235|238,238|241,241|246,248|259,263|265,272 Q:0,4|6,9|11,12|21,21|25,26|28,28|39,39|42,51|54,54|60,62|64,69|71,72|74,83|90,95|99,104|114,117|131,132|134,138|146,149|151,155|157,157|207,207|209,209|213,216|220,222|231,231|236,237|239,240|242,245|249,258|264,264|273,277 EEEEE?TTEE?TT--------S???TT?E----------E??HHHHHHHHHH--H-----HTS-EEEEEE-EE?SSHHHHHHHH------HHHHHH?--SEEEEE?????????HHHH-------------HH-HHHSE-------EEEE?BSEES?T-------------------------------------------------T?E---EEEE---TTE--------E----EE-EE?SSHH---HHHHHHHHHH-----H--------HHHHH 2F7W|A PF00995.18_Sec1_seed 150 1346 !Q:0,0|6,8|19,20|29,29|34,52|58,103|113,113|115,116|124,124|128,146|150,186|190,190|202,224|236,248|259,266|270,272|279,283|285,294|296,324|328,331|336,336|338,421|424,429|433,433|439,442|452,452|458,471|476,476|479,530|537,538|548,555|562,562|567,569|576,608|610,611|620,620|627,629|640,641|644,646|651,699|703,704|706,707|709,709|726,728|739,740|742,742|744,785|792,792|798,798|822,825|829,829|840,840|847,855|861,862|868,872|874,874|878,878|880,884|886,888|901,904|907,911|913,913|925,926|928,930|935,939|950,952|954,955|957,991|995,1013|1016,1018|1024,1033|1035,1060|1065,1093|1103,1129|1133,1136|1141,1141|1146,1252|1261,1261|1263,1263|1272,1272|1279,1310|1313,1314|1324,1336|1343,1343|1346,1346 Q:1,5|9,18|21,28|30,33|53,57|104,112|114,114|117,123|125,127|147,149|187,189|191,201|225,235|249,258|267,269|273,278|284,284|295,295|325,327|332,335|337,337|422,423|430,432|434,438|443,451|453,457|472,475|477,478|531,536|539,547|556,561|563,566|570,575|609,609|612,619|621,626|630,639|642,643|647,650|700,702|705,705|708,708|710,725|729,738|741,741|743,743|786,791|793,797|799,821|826,828|830,839|841,846|856,860|863,867|873,873|875,877|879,879|885,885|889,900|905,906|912,912|914,924|927,927|931,934|940,949|953,953|956,956|992,994|1014,1015|1019,1023|1034,1034|1061,1064|1094,1102|1130,1132|1137,1140|1142,1145|1253,1260|1262,1262|1264,1271|1273,1278|1311,1312|1315,1323|1337,1342|1344,1345 ?EEEEE--?HHHHHHHHHH??HHHHHTTT-EEEE-------------------EESSS--------------------------??---------------???TTSEEEEEE?S?-HHHHHHH-HHH-------------------TSS-------------------------------------SSS?SSSSEEEEESS------------------???--HHHHHHHHTSG-------------GGGGEEEEEE----????SEE---EETTEE-----E?-----?--?T-----------------------------THH----HHHH?G------------------------------------------------------------------------------------GG------STT?HHHHH----HHHHHHHHH-HHHTT?-----------??EEEE?TT----------------------------------------------------STHHHH--HHHHHHHHH--------HHHHHT?TTTT?--SSSTTS--------------------------------?E--EEEEEGGG?SSTTTS???BHHHHHHHHS??GG---GEEE?----------?????????--------------------------??-EEE??T--T?HHHHHHTTSBTTTHHH---HHHHHHHHHH--T-T---???-----------------------??????????-??TTTTTH-HHHHH-HHHHHHHHHHHHHHHHHHHHHHT----HHH-HHHHHHHHHH-SSHHHH?-----???TTTST--HHHHH-----H?SSS?H-----H---HHHHHHHHHHHH----HT----?B?HHHHHHHHHHT--T-??HHHH-----HHHHHGGGGT???B--S---------------------------------?-TTS-------------??-???TT---SGGGS????------S------------------------??SSSS??-??-----------------------?HHHHHHHHH---------------------------HTT???-SSSS?BSSS---------------------------?-???-??????????????????-------------------------------------------????????----?EEEEEEET?B?HHHHHHHH-HHHTSS?-------------------------------SS?-EEEEEESSB?-----------?HHHHHH-HH- 1MQS|A PF00996.13_GDI_seed 9 493 !Q:0,1|4,9|15,16|26,26|33,34|39,39|45,45|49,49|52,52|63,91|93,95|99,100|104,105|110,111|132,133|137,138|145,153|160,162|170,170|174,174|191,192|195,195|200,200|202,203|218,219|232,233|257,258|262,265|273,273|290,290|296,299|302,304|307,307|310,312|316,316|323,323|329,329|333,333|335,337|345,345|357,358|361,363|367,367|374,374|376,376|382,382|385,385|399,399|402,402|411,412|415,415|428,428|430,430|445,446|451,451|455,459|461,461|482,492 Q:2,3|10,14|17,25|27,32|35,38|40,44|46,48|50,51|53,62|92,92|96,98|101,103|106,109|112,131|134,136|139,144|154,159|163,169|171,173|175,190|193,194|196,199|201,201|204,217|220,231|234,256|259,261|266,272|274,289|291,295|300,301|305,306|308,309|313,315|317,322|324,328|330,332|334,334|338,344|346,356|359,360|364,366|368,373|375,375|377,381|383,384|386,398|400,401|403,410|413,414|416,427|429,429|431,444|447,450|452,454|460,460|462,481 ??SB-----?SEEEE??SHHHHHHHH-HHHHTT??EEEE?SSSSS?TTS?EE?SHHHHHHHTT??---------------------------S???GGG??GGG??EESS??BEETTSHHHHHHHHHTGGGS??EEE??EEEEEE---------TTEEEE???SHHHHHH?SSS?HHHHHHHHHHHHHHHH??TT?GGGS?S??TTTSBHHHHHHHTT??HHHHHHHHHHTS??SSSGGGGSBSHHHHHHHHHHHHT??GGG??--SEEEETT?TTHHHHHHHHHHHHHT?EEESS????EE??-BT-TB???EEE-TTEEEB?SEEEE?GGG?G---GGEEEEE-EEEEEEEEESS??TT---SSS?SSEEEE-E?GGGGT?SS?EEEEEEEGGGTSS?TT?EEEEEEEE??SS?HHHHTHHHHHHH?S?SEEEEEEEEEEEES??STTT?EEE?????S?SBSHHHHHHHHHHHHHHHSS??????????? 3P1W|A PF00998.18_RdRP_3_seed 33 544 !Q:4,4|6,10|13,16|18,23|30,30|32,32|39,40|52,53|55,75|85,85|93,93|95,99|108,108|111,113|119,119|122,122|128,128|130,130|146,146|150,152|158,160|164,165|171,175|180,181|197,198|214,215|230,230|239,239|247,248|264,265|269,269|283,283|288,288|292,294|300,300|302,303|330,331|349,351|371,372|376,379|386,387|389,390|400,401|404,405|412,413|428,429|431,432|464,465|468,471|484,484|497,497|503,503|506,507|523,525 Q:0,3|5,5|11,12|17,17|24,29|31,31|33,38|41,51|54,54|76,84|86,92|94,94|100,107|109,110|114,118|120,121|123,127|129,129|131,145|147,149|153,157|161,163|166,170|176,179|182,196|199,213|216,229|231,238|240,246|249,263|266,268|270,282|284,287|289,291|295,299|301,301|304,329|332,348|352,370|373,375|380,385|388,388|391,399|402,403|406,411|414,427|430,430|433,463|466,467|472,483|485,496|498,502|504,505|508,522|526,543 SEEE?S?????SS????B????--HHHHHH?S?GGGEEE??GGGHHHHHHHH??B??-?----???----------HHHHHHHHH-HHHHHTT?B?????HHHHHHTS?TT???BTTTB?HH-HHHHT?H-HHHHHHHHHHHHHHH?SSS???EEEEE???EEE??GGGTS?????EEEE??HHHHHHHHHHHHHHH--HHHHHHHHGGGBGGG??HHHHHHHHHHHHHT?SSEEEEEE?BTTHHHH??HHHHHHHHHHHHTSB??HHH-HHHHHHHHHHTTT?EEEE?TTS?--EEEEE?S??TTSTTHHHHHHHHHHHHHHHHHHHTT-?EEEEEEEETTEEEEEEE???HHHHHHHHHHHHHHHHHTS??BSS????BSSGGG??B--TTBEEEEEE?-TT??EEEEEE??SHHHHHHHHHHHHS??S??HHHHHHHHTTTSHHHHHTHHHHHHHHHHHHT?-TT?--?EEEEETTEEEEE?GGGHHHHHHHHH?GGGGT?BS??HHHHHHHHHHHHHHT???HHHHHHHHHHHHHHHHTS 4GMC|A PF00999.16_Na_H_Exchanger_seed 80 593 !Q:13,14|16,16|22,26|28,35|52,63|65,94|116,117|121,121|129,142|158,169|176,184|188,193|205,205|207,209|219,223|227,227|259,265|270,271|275,289|309,309|316,316|320,326|328,329|331,331|344,345|353,353|356,356|370,380|388,390|394,397|403,406|421,436|441,448|450,450|466,466|468,468|480,496|498,498|506,508|512,512|516,518|533,538|540,540|542,542|544,557|560,560|583,589 Q:0,12|15,15|17,21|27,27|36,51|64,64|95,115|118,120|122,128|143,157|170,175|185,187|194,204|206,206|210,218|224,226|228,258|266,269|272,274|290,308|310,315|317,319|327,327|330,330|332,343|346,352|354,355|357,369|381,387|391,393|398,402|407,420|437,440|449,449|451,465|467,467|469,479|497,497|499,505|509,511|513,515|519,532|539,539|541,541|543,543|558,559|561,582|590,592 HHHHHHHHHHHHH--H-HHTTT---??H--------HHHHHHHHHHHSTTTT?---------?-S???---------------------------HHHHHHHHHHHHHHHHHHHHT??HHH-HHTTHHH--------------HHHHHHHHHHHHHHH------------HHHHHH---------HHT?----?HHHHHHHHHHH-H???HHHHHHHHH-----HTT?TTSHHHHHHHHHHHHHHHHHHHHHHHHHHHH-------HTSS??HHH---------------HHHHHHHHHHHHHHHHHHH-TSTTTS?GGG-------S??S?HHHHHHHHHHHH--HHHHHHH-TS?HHHHHHHHHHHTT-----------TSHHHHT--?HHH----HHHHH----HHHHHHHHHHHHHT??--------------TTST--------T?SHHHHHHHHHHHHHH-H-HHHHHHHHHTG-----------------G-GHHHHHH---HHH-HTT???HHHHHHHHHHHHHT------T?S?H--------------HH-HHHHHHHHHHHHHHHHHHHHHH-------HHH 4BWZ|A PF01000.21_RNA_pol_A_bac_seed 59 196 !Q:6,6|10,10|22,22|24,26|31,50|54,54|59,60|64,64|73,73|76,85|93,93|100,100|104,105|108,109|117,119|122,141|145,145|150,151|154,154|156,156|167,167|171,171|174,193|195,196 Q:0,5|7,9|11,21|23,23|27,30|51,53|55,58|61,63|65,72|74,75|86,92|94,99|101,103|106,107|110,116|120,121|142,144|146,149|152,153|155,155|157,166|168,170|172,173|194,194 EEEEEE?SSS?HHHHHHHHHHS?B???TTSS----------------????SSS?HHHH??TTT?EEEEEEEE?EE??????????HHHHEES?EEEGGG?EEE??TT?-SSTTSSS???BS--------------------STT?EEEE??TT?E-EEEEEEEEEE?TTT?GG--------------------G?- 1K83|C PF01002.14_Flavi_NS2B_seed 30 131 !Q:0,46|55,59|62,62|65,69|76,76|80,80|86,119|121,129 Q:47,54|60,61|63,64|70,75|77,79|81,85|120,120|130,130 ---------------?????---------------------------SEEEEEEE?????SS?EE?????EEEEEE?SSS?EEETT???????-------??????--------??????B??--?????S 2GGV|A PF01003.14_Flavi_capsid_seed 27 127 !Q:0,17|35,36|38,39|51,53|57,60|71,71|94,95|98,126 Q:18,34|37,37|40,50|54,56|61,70|72,93|96,97 ??????????????????SSSTHHHHHHTSSSTTS??S??HHHHHHHHHHH---HHT????HHHHHHHTSS?SHHHHHHHHHHHHHHHHHHHHH--TS???-------------------------- 1R6R|A PF01004.14_Flavi_M_seed 30 76 !Q:0,0|5,5|7,7|11,13|16,18|39,39|55,55|71,75 Q:1,4|6,6|8,10|14,15|19,38|40,54|56,70 ?TTSS?S?TTS???SS?-?SSSSHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHSS?STHHHHHHHHHHHHH????? 3J2P|B PF01007.15_IRK_seed 13 378 !Q:1,1|5,5|7,13|17,17|33,33|65,65|68,68|71,86|91,98|103,104|120,122|126,126|128,128|131,131|162,162|173,173|198,198|214,214|217,218|228,228|236,236|239,241|244,244|251,252|255,255|260,261|266,266|269,271|285,286|306,308|312,314|321,321|327,327|331,331|333,335|338,339|341,341|351,354|359,377 Q:0,0|2,4|6,6|14,16|18,32|34,64|66,67|69,70|87,90|99,102|105,119|123,125|127,127|129,130|132,161|163,172|174,197|199,213|215,216|219,227|229,235|237,238|242,243|245,250|253,254|256,259|262,265|267,268|272,284|287,305|309,311|315,320|322,326|328,330|332,332|336,337|340,340|342,350|355,358 B?TTS?B???????SSH-HHHHHHTHHHHHTTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?TT?TT---------------?BTTB??------SBTT??SHHHHHHHHHHHHHT???SSS?B?SS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?GGGGGGSEEE?SSEEEEEETTEEEEEEEEEESSSS?EEEEEEEEEEEEEEE?TT??EEEEEEEEE?SSGGGTT-TB???SS?EEEEEE??TT?TTTT??HHHH-TT???EEEEEEEEEETTT??EEEEEEEEETTTEEETEEE???EEE--?SSSEEE?GGGSS?EEE?T---TS??S?HHHHHHHHH----HHTT??--------------??? 1N9P|A PF01008.12_IF-2B_seed 18 445 !Q:2,2|23,27|29,29|34,42|57,57|60,60|73,79|84,84|94,132|144,144|160,170|173,173|178,178|180,182|191,191|200,200|206,225|231,232|235,235|252,253|258,258|269,270|272,273|279,280|288,289|308,309|314,315|320,320|323,325|329,332|334,335|347,347|349,349|351,415|417,417|420,421|432,432|443,443|445,445 Q:0,1|3,22|28,28|30,33|43,56|58,59|61,72|80,83|85,93|133,143|145,159|171,172|174,177|179,179|183,190|192,199|201,205|226,230|233,234|236,251|254,257|259,268|271,271|274,278|281,287|290,307|310,313|316,319|321,322|326,328|333,333|336,346|348,348|350,350|416,416|418,419|422,431|433,442|444,444 SS?SHHHHHHHHHHHHHHHTTSS?---?S?HHHH---------HHHHHHHHHHHHTT?TT?HHHHHHHHHHHH-------HHTT?SSHHHHHHH---------------------------------------HHHHHHHHHHH-HHHHHHHHHHHHHTT?---------?TT?EEEE?S-??SSSSSSSS?SHHHHHHH-HHHTT-----------------???EEEEE??TT-TTHHHHTHHHHHHHTT??EEEE?GGGHHHHHHT--T??SEEEE??SEEETTE--EEEETTHHHHHHHHHHTT??EEEE??GGGB?TT-??GGG????B??THHHHEETTEE?S?T-----------------------------------------------------------------T?EE??BSEEEEEGGG?SEEEETTEEE?S- 2A0U|A PF01011.16_PQQ_seed 130 41 !Q:6,8|21,23|30,30|33,35|37,38 Q:0,5|9,20|24,29|31,32|36,36|39,40 TEEEEE--?TTSEEEEEETTT-??EEEEEE?SS???S??EE 3Q7M|A PF01012.16_ETF_seed 174 244 !Q:5,7|9,10|12,17|22,23|38,41|43,49|51,52|58,64|67,70|72,73|81,85|91,92|99,99|105,109|124,129|131,134|136,137|150,153|164,166|171,173|178,179|182,200|202,203|210,212|216,216|224,227|235,235|237,238|242,243 Q:0,4|8,8|11,11|18,21|24,37|42,42|50,50|53,57|65,66|71,71|74,80|86,90|93,98|100,104|110,123|130,130|135,135|138,149|154,163|167,170|174,177|180,181|201,201|204,209|213,215|217,223|228,234|236,236|239,241 EEEEE??-E--E------TTEE?-THHHHHHHHHHTTT----S-------E--EEEEE-------EE----S??HHHHHHH-----HHSTT??EEEEEE?GGGTT?---?HHHHHHHHHHHHHH------H?--?S--EEEEESSHHHHH----HHHHHHHHHT???EEEE?--EEEE--TT-------------------E--EEEEET---TTT-EEEEEEE?--?SSEEEEE?G--GGS?? 1O94|C PF01014.13_Uricase_seed 122 215 !Q:17,17|19,24|28,32|36,37|49,52|61,61|67,72|81,98|108,111|113,115|118,118|132,132|135,135|138,138|149,150|154,165|171,194|199,201|205,206|208,209 Q:0,16|18,18|25,27|33,35|38,48|53,60|62,66|73,80|99,107|112,112|116,117|119,131|133,134|136,137|139,148|151,153|166,170|195,198|202,204|207,207|210,214 EEEEEEEEEEEEESSSB?B?-????STT?????BSS??EEEEEEEEEEE--??BSSHHHHH-HTHHH------HHHHHHHH------------------HHHHHHHHH----H-??BS?HHHHHHHHHHHHH-HH?TT-EEEEEEEEEE??EEE??-?--------TTTTT??-----------------?----SGGG???EEE??S??EEEEE 1WRR|A PF01015.13_Ribosomal_S3Ae_seed 69 243 !Q:0,11|15,15|24,25|28,28|30,33|36,36|45,46|51,51|59,59|68,68|71,71|73,73|75,77|80,80|90,90|94,95|106,107|115,116|120,120|130,130|134,134|136,136|145,148|151,155|158,162|185,185|195,208|219,219|225,227|240,242 Q:12,14|16,23|26,27|29,29|34,35|37,44|47,50|52,58|60,67|69,70|72,72|74,74|78,79|81,89|91,93|96,105|108,114|117,119|121,129|131,133|135,135|137,144|149,150|156,157|163,184|186,194|209,218|220,224|228,239 ????????????SST-TEEEEEEE??SS-S----SS?EEEEEEEE??BTTB?TTHHHHT?EEEEEHHH-HH?S-S--?SS?EEEEEEEEE-ETT--EEEEEEEEEE??SHHHHHH??TTS?EEEEEEEEE?SSS?E-EEEEEEEE????TT??---SS?????HHHHHHHHHHHHHHHHHHHHSS?HHHHHHHHT--------------TTHHHHHHHH-HHTTT???EEEEEEEEEEEE??? 2XZM|4 PF01016.14_Ribosomal_L27_seed 88 91 !Q:0,18|20,20|23,23|26,29|32,33|35,38|40,40|45,45|47,47|50,54|57,62|68,76|80,86|88,88 Q:19,19|21,22|24,25|30,31|34,34|39,39|41,44|46,46|48,49|55,56|63,67|77,79|87,87|89,90 ???????-????-??????S?SS?SS????TT??S????S?SSSS?B?SS?????TT??????SSSEE?????----SSS?---???B?EE 2ZJQ|T PF01017.15_STAT_alpha_seed 26 219 !Q:0,0|19,19|33,48|57,63|69,69|71,90|98,105|153,158|190,192|195,195 Q:1,18|20,32|49,56|64,68|70,70|91,97|106,152|159,189|193,194|196,218 ?HHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHH----------------HHHHHHHH-------HHHHT-T??---????????-??????HHHHHHH--------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSS-?-???THHHHHHHHHHHHHHHHHHHHHHHHHHHHHH???TT?HHHHHHHHHHHHHHHHHHHHHHH 3CWG|A PF01018.17_GTP1_OBG_seed 8 156 !Q:10,19|21,23|27,30|32,41|47,47|50,52|54,54|59,60|64,71|75,82|88,88|99,100|106,106|110,110|116,123|128,128|135,145|155,155 Q:0,9|20,20|24,26|31,31|42,46|48,49|53,53|55,58|61,63|72,74|83,87|89,98|101,105|107,109|111,115|124,127|129,134|146,154 EEEEEEEEEE??????????B???SSS????B??????????EEEEE?TT???S?GGGT??EEE????????STT????????EEEEE?TTEEEEETTT??EEEEE?STT?EEEEE????????GGGS?BTTBSS???????????EEEEEEEEE? 1UDX|A PF01019.16_G_glu_transpept_seed 52 763 !Q:6,7|9,10|26,26|30,31|42,42|46,46|49,50|53,54|57,58|60,101|103,104|117,119|122,122|137,137|140,141|156,157|166,172|176,180|183,184|189,191|194,194|197,199|212,213|215,229|237,237|239,240|249,258|262,264|266,267|269,272|279,285|289,291|297,297|300,308|314,315|335,338|343,343|346,353|375,399|405,405|416,417|420,423|425,478|483,493|495,496|503,503|506,507|515,515|523,523|525,525|529,530|532,580|582,585|591,593|600,601|604,606|623,627|631,646|654,655|658,664|669,676|680,680|682,691|693,693|702,703|707,708|712,712|714,718|724,724|726,748|751,751|757,757 Q:0,5|8,8|11,25|27,29|32,41|43,45|47,48|51,52|55,56|59,59|102,102|105,116|120,121|123,136|138,139|142,155|158,165|173,175|181,182|185,188|192,193|195,196|200,211|214,214|230,236|238,238|241,248|259,261|265,265|268,268|273,278|286,288|292,296|298,299|309,313|316,334|339,342|344,345|354,374|400,404|406,415|418,419|424,424|479,482|494,494|497,502|504,505|508,514|516,522|524,524|526,528|531,531|581,581|586,590|594,599|602,603|607,622|628,630|647,653|656,657|665,668|677,679|681,681|692,692|694,701|704,706|709,711|713,713|719,723|725,725|749,750|752,756|758,762 HHHHHH--T??HHHHHHHHHHHHHHH?TTT??SSSEEEEEEE?TTS?EE--EE--EE??B???????-----???------?????????????????-???B??HHHHHHHHHHHH?--SS?HHHHHHHHHHHHHH?EE??HHHHHHHHHTHHHH--STTSHHHH-------HHH-----EE--TTEE-??TT?EE?-?HHHHHHHHHHHH--H?--------------THHHHHS-H--HHHHHHHH----------HHH---S--S????HHHHHT??---?-EEE??-EEEEE-TT---------EEEEE??TTBSSHHHHHHHHHHHHTS?---SSSS?TT?-------HHHHHHHHHHHHHHHHHHGGG??--------??????----??---GGGGG?HHHHHHHHHH??SS????H------------------------------------------------------HHHS????????--?S??EEEEEE?TT??EEEEEEE?SSTTTTS?B?GGG??B?????????-????????????-?????------------?????????B????EEEEE---TTEEEE--EE???STTHHHHHHHHHHHHH-----HTS???-------------HHHHHHS??EE?-----?TTTT-------?EEE?S---------?S?HHHHHHHH--HTT??EEE?S?????EEEEE?T-----------------------TS?EEEEE?TTSTT 3GA9|L PF01020.12_Ribosomal_L40e_seed 3 52 !Q:0,2|16,16|23,24|27,27|30,31|33,35|41,41|43,43|47,51 Q:3,15|17,22|25,26|28,29|32,32|36,40|42,42|44,46 ???HHHHHHHHHHHTS?EEETTT??EE?TT??S???GGGTS?S?EEE????? 3J39|m PF01022.15_HTH_5_seed 42 51 !Q:0,0|13,18|20,20|31,31 Q:1,12|19,19|21,30|32,50 ?HHHHHHHHHHTT---??-B?HHHHHHHHTS?HHHHHHHHHHHHHTTSEEE 1R1U|A PF01023.14_S_100_seed 24 44 !Q:15,15|18,18|21,21|23,23 Q:0,14|16,17|19,20|22,22|24,43 HHHHHHHHHHHHHHS?SS?SS?S?EEHHHHHHHHHHHHTTTHHH 2WCB|A PF01024.14_Colicin_seed 14 200 !Q:0,5|30,30|47,47|50,54|72,74|88,89|101,101|105,106|127,129|144,145|164,165|167,167|177,177|188,188 Q:6,29|31,46|48,49|55,71|75,87|90,100|102,104|107,126|130,143|146,163|166,166|168,176|178,187|189,199 ??????SHHHHHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHHHT?TT?????HHHHHHHHHHHHTSGGG???HHHHHHHHHHHHT??HHHHHHHHHHH?GGG??TTHHHHHHHHHHHHHHHHHH???HHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHHH??S?HHHHHHHHH-HHHHHHHHHH?THHHHHHHHHT 1A87|A PF01025.14_GrpE_seed 111 286 !Q:0,60|75,81|85,89|92,93|99,108|116,116|123,124|130,130|144,146|153,155|163,164|166,176|181,187|193,194|207,207|214,218|220,220|223,225|231,232|238,247|250,250|252,252|254,254|263,265|269,269|272,276|278,278|285,285 Q:61,74|82,84|90,91|94,98|109,115|117,122|125,129|131,143|147,152|156,162|165,165|177,180|188,192|195,206|208,213|219,219|221,222|226,230|233,237|248,249|251,251|253,253|255,262|266,268|270,271|277,277|279,284 ?????????????????????????????------------????????????????????HHHHHHHHHHHHHH-------HHH-----HH--HHHHH----------HHHHHHH-HHHHHH--HHHHH-HHHHHTTHHHHHH---HHHHHH---HHHHHHS??S---------??STHH-------HHHHH--HHHHHHHHHHHH-HHTTEE????-S-SS???TTTEE--EEEEE--------??SS-S?S-SSEEEEEE???EET-TS---??S?EEEEEE? 3A6M|A PF01026.16_TatD_DNase_seed 98 580 !Q:5,5|9,9|13,28|32,43|49,49|52,56|62,63|66,66|68,95|99,99|102,117|119,119|123,124|133,135|138,138|144,146|148,150|156,191|196,205|209,210|214,216|218,218|232,236|238,247|249,254|256,256|258,258|260,270|276,276|289,289|291,292|300,306|309,317|324,347|352,352|357,360|366,411|413,413|425,431|436,436|441,441|444,447|449,453|459,460|464,464|471,473|477,511|514,514|516,523|525,525|527,529|543,543|547,561|578,579 Q:0,4|6,8|10,12|29,31|44,48|50,51|57,61|64,65|67,67|96,98|100,101|118,118|120,122|125,132|136,137|139,143|147,147|151,155|192,195|206,208|211,213|217,217|219,231|237,237|248,248|255,255|257,257|259,259|271,275|277,288|290,290|293,299|307,308|318,323|348,351|353,356|361,365|412,412|414,424|432,435|437,440|442,443|448,448|454,458|461,463|465,470|474,476|512,513|515,515|524,524|526,526|530,542|544,546|562,577 EEEEE?TTS-GGG----------------TTT------------HHHHH-HH-----HHHTT??EE-E----------------------------EEE?SH----------------H-HHH--HHHHHHHH--?TT-EEEEE???G---GGGGG---------------------------------?-?HHHH----------HHH--HHH---T-TSTTEEEEEEEEE-----E?---------S----??S-S?H-----------HHHHH-HHHHHHHHHHHH-T??EEEEEES------?HH---------HHHHHH------------------------HHTT-GGGT---?EEETT--------------------------------------------??S?HHHHHHHHHTS-----??EEEE?GGGG?SS--??H-----HHHHH--HHS?TTTEEE???TTS???--------------------------------TT?T--------T-S???GGGHHHHHHHHHH-HTT-------------??HHHHHHHHHHHHHHHH-? 2GZX|A PF01028.15_Topoisom_I_seed 134 535 !Q:8,18|39,39|47,56|58,58|60,60|63,63|76,91|94,102|107,111|115,115|120,122|128,199|212,212|216,216|224,228|240,248|251,255|262,274|277,310|323,332|335,345|362,366|371,472|475,476|491,534 Q:0,7|19,38|40,46|57,57|59,59|61,62|64,75|92,93|103,106|112,114|116,119|123,127|200,211|213,215|217,223|229,239|249,250|256,261|275,276|311,322|333,334|346,361|367,370|473,474|477,490 TTSHHHHH-----------HHHHHHHHHHHHHHHHHHHH-HHHHHHT----------T?S?HH-HHHHHHHHHHHH----------------HH?????????TTTS?????GGG?BGGG??-EEEEE------------------------------------------------------------------------TTEEEEEEEEEE?GGG?EEEEEEE---??HHHHHHHHHTT---------TT---??TTSBTT-------------TT??--------------------------------HHHHHHHHHHHS----------TT---------??HHHHHHHHHHHHHHHH-----HHHH?--------------------------------------------------------------------------------------------------?--TT??HHHHHHHHHHHHHH???????????-???????????????????????????????? 3M4A|A PF01029.13_NusB_seed 114 179 !Q:2,4|6,9|23,23|27,49|58,72|76,76|79,79|105,105|107,107|111,111|116,116|133,135|137,137|140,140|156,158|160,160|166,167 Q:0,1|5,5|10,22|24,26|50,57|73,75|77,78|80,104|106,106|108,110|112,115|117,132|136,136|138,139|141,155|159,159|161,165|168,178 HH---H----HHHHHHHHHHHTT?TTS----------------------?HHHHHHHH??-------------TTS?HH-HHHHHHHHHHHHHHHHHHHHHHHHT-T?SSS?TTTS?HHHHHHHHHHHHHHHH--?T-TS?HHHHHHHHHHHHHHH---S?HHHHH--HHHHHHHHHHH 3D3B|A PF01030.19_Recep_L_domain_seed 68 175 !Q:1,2|7,10|16,18|21,45|51,52|57,57|63,68|70,73|76,77|80,81|84,84|88,92|100,101|103,117|119,124|127,130|133,133|135,144|150,151|153,159|161,162|167,167|169,169 Q:0,0|3,6|11,15|19,20|46,50|53,56|58,62|69,69|74,75|78,79|82,83|85,87|93,99|102,102|118,118|125,126|131,132|134,134|145,149|152,152|160,160|163,166|168,168|170,174 T??EEES----BEEEE???TT----------------------???GGGTT??EESS?EEEES?---??S????TT??EE??SS?BTT-----TEEEEEE??S???????????????S??????TT--??EE?S---------?EEEEE??T-------T??SGGG-S?HHHHB 3U2P|A PF01031.15_Dynamin_M_seed 93 326 !Q:0,112|135,135|139,152|156,157|177,177|181,182|192,209|249,252|254,254|257,257|292,325 Q:113,134|136,138|153,155|158,176|178,180|183,191|210,248|253,253|255,256|258,291 ??????????????????????-???????????????????????????????????????????????????????????????????????????????-?????---??HHHHHHHHHHHHHHHHHHHHHH-HTT????---------?SSS??HHHHHHHHHHHHHHHHHHH-HHH--HHHHHHHHH??????????????????HHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHH----H?TT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT-??????????????--???????-----????? 3ZVR|A PF01032.13_FecCD_seed 145 429 !Q:2,3|6,9|15,17|19,22|24,74|108,108|111,112|131,148|151,162|171,172|179,181|187,187|191,197|201,203|227,227|230,234|237,250|262,265|267,267|269,270|275,275|292,292|303,303|312,313|337,340|353,355|358,363|365,365|394,394|396,403|406,407|420,423|427,428 Q:0,1|4,5|10,14|18,18|23,23|75,107|109,110|113,130|149,150|163,170|173,178|182,186|188,190|198,200|204,226|228,229|235,236|251,261|266,266|268,268|271,274|276,291|293,302|304,311|314,336|341,352|356,357|364,364|366,393|395,395|404,405|408,419|424,426 HH--HH----HHHHH---H----H????---???????????????---------------------------??TTTTTTHHHHHHHHHHHHHHHHHHHHHHHHHTT?TT??TTTTTHHHHHHHHHHHHH????--------??????HH------------HHHHHHHH--HHHHHH---HHHHH-HHH-------HHS???HHHHHHHHHHHHHHHHHHHHHHH-HH?---?SH--------------HHHHHHHHTTT??--T-T??HHHH-HHHHHHHHHHHHHHHH-THHHHHHGGG?HHHHHHTT??HHHHHHHHHHHHHHHHHHHHHHH????STTTHHHHHHHT---TS----?-S?HHHHHHHHHHHHHHHHHHHHHHHTTSST-T??-?---?HH--HHHHHHHHHHHH----HHH?? 4G1U|A PF01033.12_Somatomedin_B_seed 73 58 !Q:0,3|8,10|13,16|20,29|31,33|40,40|43,45|53,57 Q:4,7|11,12|17,19|30,30|34,39|41,42|46,52 ????STTT---TT????TTS----------S???STTGGG-TT???TTHHHHT????? 4GTW|A PF01035.15_DNA_binding_1_seed 93 130 !Q:0,0|10,12|16,16|18,18|21,22|24,24|30,33|38,44|47,47|56,58|61,61|63,66|72,72|77,78|81,92|94,97|100,107|112,113|116,116|125,129 Q:1,9|13,15|17,17|19,20|23,23|25,29|34,37|45,46|48,55|59,60|62,62|67,71|73,76|79,80|93,93|98,99|108,111|114,115|117,124 ?HHHHHHHHH---HTT-S?TT??B?HHHHH----HHTT-?-----TT?HHHHHHHH---HT?S----BTTTS?GGGB??TT??-------???T----TT--------HHHH--HH-HHHHHHHT??--? 4ENM|A PF01036.13_Bac_rhodopsin_seed 17 275 !Q:24,26|54,54|66,79|84,85|99,102|113,133|157,158|164,168|189,189|200,200|205,205|219,221|237,238|240,240|270,274 Q:0,23|27,53|55,65|80,83|86,98|103,112|134,156|159,163|169,188|190,199|201,204|206,218|222,236|239,239|241,269 HHHHHHHHHHHHHHHHHHHHHHTS???HHHHHHHHHHHHHHHHHHHHHHHHHTT?SEEEEEETTEE--------------EEEE--THHHHHHHHHHHH----HHHHHHHHTT??-------------------HHHHHHHHHHHHHHHHHHHHHHH?-SSHHH-----HHHHHHHHHHHHHHHHHHHH-HTHHHHTTSS?HHHH-HHHHHHHHHHHHH---HTTHHHHHHHSTTTT??S?HHHHHHHHHHHHHHHHHHHHHHHHHSSTT????? 2NTW|A PF01037.16_AsnC_trans_reg_seed 263 92 !Q:4,7|9,14|28,34|46,46|56,57|71,72|79,79|83,83 Q:0,3|8,8|15,27|35,45|47,55|58,70|73,78|80,82|84,91 EEEE????S------TTHHHHHHHHHSS------?TTEEEEEEESS-SSSEEEEEE?-SSHHHHHHHTTTS--STTSSS?SEE-EEEEEEEE 2VBW|A PF01039.17_Carboxyl_trans_seed 34 616 !Q:2,2|5,5|14,14|21,22|24,24|40,42|46,47|53,55|58,62|69,69|78,78|82,82|89,89|101,101|124,125|129,133|155,155|158,158|164,164|166,166|179,179|187,190|195,195|201,214|219,219|221,225|263,263|269,283|286,286|288,288|290,308|310,310|313,315|322,322|331,335|338,338|341,342|350,350|371,372|374,374|380,382|385,385|388,390|396,396|401,401|420,422|426,428|433,434|457,458|460,460|466,466|469,469|480,480|487,487|496,496|498,498|504,504|514,514|526,526|530,558|593,593|599,599 Q:0,1|3,4|6,13|15,20|23,23|25,39|43,45|48,52|56,57|63,68|70,77|79,81|83,88|90,100|102,123|126,128|134,154|156,157|159,163|165,165|167,178|180,186|191,194|196,200|215,218|220,220|226,262|264,268|284,285|287,287|289,289|309,309|311,312|316,321|323,330|336,337|339,340|343,349|351,370|373,373|375,379|383,384|386,387|391,395|397,400|402,419|423,425|429,432|435,456|459,459|461,465|467,468|470,479|481,486|488,495|497,497|499,503|505,513|515,525|527,529|559,592|594,598|600,615 SS?TT?EEEEEEEE?TTSGGG?-B?HHHHHHHHHHHHHHH---HHT??EEEEE???SB?????TTTTTT?EEEESSSS?GGG?EEEEEE?HHHHHHHHHTT?GGGEEEEEEEETTEEEEEEEEE??SSS?----SSHHHHHHHHHHHHHHHHHHT-TS?EEEEE?S?EETHHHHHHHHT?EEEEETT--??EESS?HHHHH--------------HHHT-S?????SHHHHSHHHHHHHTSSSEEESSHHHHHHHHHHHHTTS?SSTTS--------???????SS?S?S------?------??????T-TS???HHHHHH?EEETTEEE---??SS?TT??EEESTTS?TTEEEEEEEETTEEEEEEEE??S?EEEEE???TT?TT???EEEEE?TTEE?HHHHHHHHHHHHHHHTTT???EEE???BSEE??SHHHHHTTHHHHHHHHHHHHHT??S?EEEEE?TT?EEEHHHHHTT?GGGSTT-TEEEEEET-T?EEESS?HHHHHHHHS?HHHHHHHHHHH?TTT????????????-------??????????TTHHHHHHHHHHHHHHHHHHHHTTSSHHHHHHTT?SSEEE?GGGHHHHHHHHHHHHH 1UYS|A PF01041.12_DegT_DnrJ_EryC1_seed 38 472 !Q:0,2|16,20|23,29|45,47|55,55|69,69|77,78|81,81|86,86|90,90|102,102|107,108|111,116|123,123|131,132|136,140|147,147|151,155|168,168|174,174|177,177|180,182|187,205|213,214|221,221|228,230|233,233|240,240|256,277|279,281|284,285|289,289|291,291|293,295|297,299|341,345|350,363|371,371|376,376|378,379|391,392|395,396|398,399|401,405|412,412|416,424|428,430|433,433|435,436|450,451|455,459 Q:3,15|21,22|30,44|48,54|56,68|70,76|79,80|82,85|87,89|91,101|103,106|109,110|117,122|124,130|133,135|141,146|148,150|156,167|169,173|175,176|178,179|183,186|206,212|215,220|222,227|231,232|234,239|241,255|278,278|282,283|286,288|290,290|292,292|296,296|300,340|346,349|364,370|372,375|377,377|380,390|393,394|397,397|400,400|406,411|413,415|425,427|431,432|434,434|437,449|452,454|460,471 ???HHHHHHHHHHHHH?--??BS------?HHHHHHHHHHHHHHT--?SEEEEES?HHHHHHHHHHHTT?GGGGGGS??TT?EEEE?SSS?HHHHHHHHHTT?EEEE??EE------TTTTEE?GGGHHHH??TTE-----EEEEEE?GGG???-?HHHHHHHHHHHT?EEEEE?TT?TT--?EETT-------------------EETTSSS--SEEEEE?STTSSS-??SS?EEEEES?HHHHHHHHHHHBTTB???????????--?????????S???TT??GGG?B?S???B???BHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGGGTTTEE?????TTEE-----------???SSEEEEE?GGGS-S?-HHHHHHHHHHT--TB??B??T-----TSSGGG-SGG---------GSS???EE?S??HHHHHHHHHEEEE??STT??---HHHHHHHHHHHH 2VMP|A PF01042.16_Ribonuc_L-PSP_seed 30 148 !Q:0,0|4,9|12,12|15,15|19,20|31,31|34,34|36,39|42,42|45,46|70,71|75,80|89,94|110,120|127,127|129,130|132,134|137,137|147,147 Q:1,3|10,11|13,14|16,18|21,30|32,33|35,35|40,41|43,44|47,69|72,74|81,88|95,109|121,126|128,128|131,131|135,136|138,146 ?TTS?--???SS?BS-EEE--ETTEEEEEEE?SB?T----TT?SB?-SSSHHHHHHHHHHHHHHHHHHTT??GGG------EEEEEEEE?????-TTHHHHHHHHHHTTT-----?----?EEEEEE?S??G---GG?SEEEEEEEE? 3KJJ|A PF01043.15_SecA_PP_bind_seed 120 198 !Q:0,3|5,9|25,26|31,32|34,42|44,44|47,48|50,50|53,56|59,64|66,68|79,79|84,120|123,124|132,132|149,149|157,157|159,159|162,165|167,171|176,176|180,181|186,188 Q:4,4|10,24|27,30|33,33|43,43|45,46|49,49|51,52|57,58|65,65|69,78|80,83|121,122|125,131|133,148|150,156|158,158|160,161|166,166|172,175|177,179|182,185|189,197 ?-??S---??GGGHHHHTTGGGSBT--TBSS??S---------S?TT??S?SS????TT??????S---SSSGGGTSSS-SSSS------------------------------------?SS??TTSGGGH-HHHHHHHHHHTTTTSS?BTTTEEE-E-TT----E-----EEEE?TTT??EESS???TTTHHHHHH 1M6N|A PF01044.14_Vinculin_seed 10 1289 !Q:0,2|26,27|33,39|64,66|97,97|100,100|150,151|183,183|215,215|219,220|250,250|253,254|290,290|314,314|343,347|354,415|460,461|463,477|488,511|523,523|550,553|557,558|586,589|594,600|615,620|622,622|642,643|672,673|710,710|725,725|727,727|730,730|761,761|763,763|798,798|828,828|854,862|864,864|893,895|926,927|932,935|960,1020|1023,1029|1031,1074|1078,1088|1093,1093|1097,1099|1116,1117|1120,1120|1143,1143|1145,1146|1178,1179|1210,1210|1216,1227|1264,1264|1267,1274|1276,1281|1283,1283|1286,1288 Q:3,25|28,32|40,63|67,96|98,99|101,149|152,182|184,214|216,218|221,249|251,252|255,289|291,313|315,342|348,353|416,459|462,462|478,487|512,522|524,549|554,556|559,585|590,593|601,614|621,621|623,641|644,671|674,709|711,724|726,726|728,729|731,760|762,762|764,797|799,827|829,853|863,863|865,892|896,925|928,931|936,959|1021,1022|1030,1030|1075,1077|1089,1092|1094,1096|1100,1115|1118,1119|1121,1142|1144,1144|1147,1177|1180,1209|1211,1215|1228,1263|1265,1266|1275,1275|1282,1282|1284,1285 ???BSTTHHHHHHHHHHHHHHHHHHH--HHHHT???????HHHHHHHHHHHHHHHHHHHHHTTT???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?TT?STHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSTT??SHHHHHHHHHHHHHHHHHHHHHHHHHHTTBS?HHHHHHHHHHHHHHHHTHHHHHHHHHHHHHH-HHS??STTHHHHHHHHHHHHHHHHHHHHHHHHTT?SS??SHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHSTTS?STTTTHHHHHHHHHHHHHHHHTT?STTHHHHHHHHHHHHHHHHHHHHHTTTT?-???HHHHHH--------------------------------------------------------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT??S-------------??SSTHHHHHHH------------------------HHHHHHHHHHS?STTTHHHHHHHHHHHHHHHHHHHHHH----HHS??SSHHHHHHHHHHHHHHHHHHHHHHHHH----HTTS???????HHHHHHHHHHHHHS??????S?SHHHHHHHHHHHHHHHHTS?-HHHHHHHHHHHHHHHHHHHHHHSSTTSS??SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS?SSHHHHHHHHHHHS?S?SS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHS-S?HHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTSTT?HHHHHHHHHHHHHHHHHHHHHHHHHHTTS?HHHHHHHHHHHHHHHHHHHHHTTSS---------S?TTTSTTHHHHHHHHHHHHHHHHHHHHHT???HHHHHHHHHHHHHHHHHHHHHHHHHHSSSS??TTTT----THHHHTTTTTTHHHHHHHHHHHHS-----------------------------------------------------------??SS------?S???????????-----??????????????????----??????TTS????-----??SSSS?SSS?-?HHHHHHHHHHHHHTTB??TT?HHHHHHHHHHHHHHHHHHTTTS?S--STTHHHHHHHHHHHHHHHHHHHHHHHHHHHB??HHHHHHHHHHHTTHHHHHHHHHHHHHHHHH?SSSTT----------??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSB?TT-------?S??????B?SS??? 1SYQ|A PF01047.17_MarR_seed 38 64 !Q:0,1|17,17|22,25|34,34|56,56|59,59 Q:2,16|18,21|26,33|35,55|57,58|60,63 ??HHHHHHHHHHHHHSE-EEHH----HHHHHHTS?HHHHHHHHHHHHHTTSEEEEE?SS?TTSE 3CDH|A PF01048.15_PNP_UDP_1_seed 159 504 !Q:0,0|6,6|9,20|27,27|32,35|45,63|71,77|88,94|98,98|100,101|105,105|115,116|119,141|143,144|153,160|163,167|171,180|183,183|190,194|196,202|205,210|217,218|220,222|224,224|226,228|231,273|276,276|279,281|284,286|288,288|298,306|313,335|342,345|351,353|356,374|380,382|389,396|398,402|405,405|420,420|422,424|426,430|433,433|439,442|446,447|449,456|458,484|496,497 Q:1,5|7,8|21,26|28,31|36,44|64,70|78,87|95,97|99,99|102,104|106,114|117,118|142,142|145,152|161,162|168,170|181,182|184,189|195,195|203,204|211,216|219,219|223,223|225,225|229,230|274,275|277,278|282,283|287,287|289,297|307,312|336,341|346,350|354,355|375,379|383,388|397,397|403,404|406,419|421,421|425,425|431,432|434,438|443,445|448,448|457,457|485,495|498,503 ?EEEEE?TT-----------?GGGGGG?EEEE----EEEGGGSTT?????--------??????EEEEEEE-------TTEEEEEEES??----?GGG-T??HHH-HTHHHHHHH--HT-----------------------T??EEEEEEEE--------EE?----STT--??------TT?EEEEEE-----E-------EE------HHHHTT??T---T?S???TT-------------------------------------------TS?SS???TT?--B?HHHHHHHHH---------HHHHHT?----------------------GGGEEE----EEEEE???SS???----------------HHHHH---HHHHTT-------?S-----EE-ESSSHHHHHHHHHT-T--?E-----EE-EEEEE----EEE??T--------T????????------------???????HHHHHHHHHHH--HHHHHH 4EB8|A PF01049.12_Cadherin_C_seed 64 228 !Q:0,88|93,97|99,132|152,152|155,155|158,159|164,227 Q:89,92|98,98|133,151|153,154|156,157|160,163 ???????????-----------????---???-??????????????---?---??-?????????????---------------????EEEE?????S????-----????---------------------SSGGGHHHHHHHHHHHHHH?SS-SS??EEEE???---?????--------??????????-???-?????--?????-????????????????? 3IFQ|C PF01051.16_Rep_3_seed 166 425 !Q:0,8|12,12|18,25|27,27|41,70|74,78|87,90|92,93|97,98|100,100|113,113|115,117|120,138|143,144|147,149|151,152|155,155|159,163|169,176|185,186|189,189|200,202|205,206|208,209|211,211|215,215|219,226|237,241|245,265|267,267|274,275|278,287|291,297|299,309|314,321|325,350|365,365|372,374|378,385|390,390|398,398|400,402|405,411|414,416 Q:9,11|13,17|26,26|28,40|71,73|79,86|91,91|94,96|99,99|101,112|114,114|118,119|139,142|145,146|150,150|153,154|156,158|164,168|177,184|187,188|190,199|203,204|207,207|210,210|212,214|216,218|227,236|242,244|266,266|268,273|276,277|288,290|298,298|310,313|322,324|351,364|366,371|375,377|386,389|391,397|399,399|403,404|412,413|417,424 ?????????HHH-HHHTT--------S?HHHHHHHHHHHHH????--??????---------------???EEE?---?HHHHHHHT----T??HHH--H-HHHHHHHHHHTT-T??-EE?-----------------?BSTT??SS??-B??EE?SEE-----EEEEE--------TTTTEEEE--EE?TTTHHHHHHH---HH--H--H-HHT?GGG???-?-??HHHHHHHHHH-----HHT--------------------?B-TTTEEE--EE----------EEH-------H-----------HHHH--------HTT??------------------------GGGGSHHHHHHHTH-HHHHHH---HTT--------TSSE-EEEEEEE-E---SS-------SS---EEEEEEEE 2NRA|C PF01052.15_SpoA_seed 130 89 !Q:1,1|17,20|28,29|32,32|36,36|39,40|44,44|50,53|65,67|72,75|85,86 Q:0,0|2,16|21,27|30,31|33,35|37,38|41,43|45,49|54,64|68,71|76,84|87,88 H-HHHTTSEEEEEEEEE????BHHHHHH??TT?EEE?SS?-SSS?EEEEE----TTEEEEEEEEE---EETT----EEEEEEEEE??TT 1O9Y|A PF01053.15_Cys_Met_Meta_PP_seed 30 475 !Q:8,11|13,14|17,17|21,22|24,26|31,31|33,40|48,50|55,56|72,74|88,88|96,96|98,98|100,100|102,106|113,114|117,121|135,136|142,142|144,147|157,158|160,161|172,172|176,180|192,193|195,197|203,203|209,209|212,213|219,221|234,234|238,240|246,246|248,248|260,299|303,304|306,307|342,346|348,351|358,358|374,374|377,378|380,381|392,401|411,411|417,417|419,421|425,425|429,429|439,439|448,449|457,458|461,461|474,474 Q:0,7|12,12|15,16|18,20|23,23|27,30|32,32|41,47|51,54|57,71|75,87|89,95|97,97|99,99|101,101|107,112|115,116|122,134|137,141|143,143|148,156|159,159|162,171|173,175|181,191|194,194|198,202|204,208|210,211|214,218|222,233|235,237|241,245|247,247|249,259|300,302|305,305|308,341|347,347|352,357|359,373|375,376|379,379|382,391|402,410|412,416|418,418|422,424|426,428|430,438|440,447|450,456|459,460|462,473 HHHHHHTT????T--TT?BSS??B???SBBB?S--------BTTBSSS-??BTTT??HHHHHHHHHHHHHHT?--SEEEEESSHHHHH-HHHHTTS?T-T?E-----EEEESS??HH-----HHHHHHHTHHHHH??EEEEE?T----TSHHHHHHH??T--TEEEEEEESS?TTT?????HHHHHHHHHHT--T--?EEEEE?TTTHH-HH??GGGGT--?SEEEEETTTTTT?SSS???EEEEE?S?HHHHHHHHHHH----------------------------------------HHH??B??HHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHTT?----T----TEEEEE?TTSTTSTTHHHHHHH?SS??S--EEEEEETTHH----------HHHHHHHHH?SSSEE?S???SSS?EEE?TTTTTTTTS?HHHHHHHT??TTEEEEE??SS?HHHHHHHHHHHH? 3GWP|A PF01055.21_Glyco_hydro_31_seed 107 1047 !Q:3,4|6,24|26,27|29,29|37,37|42,58|63,63|65,65|68,71|74,85|87,90|93,140|154,157|162,162|165,178|182,182|186,187|190,195|200,210|212,231|243,243|247,247|254,254|256,265|268,276|279,279|290,291|293,302|307,307|310,327|332,332|335,355|358,365|368,368|370,370|372,376|380,380|382,382|388,388|395,398|403,410|412,413|415,415|417,417|420,420|425,436|439,443|446,446|448,619|623,623|626,628|634,636|642,644|647,647|654,665|686,687|691,694|696,696|699,701|707,707|715,715|718,718|720,727|729,729|731,731|735,746|752,754|764,764|768,769|773,774|777,777|781,794|796,800|807,807|817,817|820,823|826,829|831,852|860,862|867,871|896,899|902,902|904,904|909,909|912,917|923,925|927,927|933,933|935,937|942,961|965,966|973,973|975,981|984,985|987,989|995,1001|1004,1004|1007,1007|1012,1014|1016,1018|1022,1023|1025,1025|1027,1028|1030,1031|1033,1034|1040,1041|1047,1047 Q:0,2|5,5|25,25|28,28|30,36|38,41|59,62|64,64|66,67|72,73|86,86|91,92|141,153|158,161|163,164|179,181|183,185|188,189|196,199|211,211|232,242|244,246|248,253|255,255|266,267|277,278|280,289|292,292|303,306|308,309|328,331|333,334|356,357|366,367|369,369|371,371|377,379|381,381|383,387|389,394|399,402|411,411|414,414|416,416|418,419|421,424|437,438|444,445|447,447|620,622|624,625|629,633|637,641|645,646|648,653|666,685|688,690|695,695|697,698|702,706|708,714|716,717|719,719|728,728|730,730|732,734|747,751|755,763|765,767|770,772|775,776|778,780|795,795|801,806|808,816|818,819|824,825|830,830|853,859|863,866|872,895|900,901|903,903|905,908|910,911|918,922|926,926|928,932|934,934|938,941|962,964|967,972|974,974|982,983|986,986|990,994|1002,1003|1005,1006|1008,1011|1015,1015|1019,1021|1024,1024|1026,1026|1029,1029|1032,1032|1035,1039|1042,1046 EEE??S-------------------S--H-HHHHHHH-HHHH?----------??????GGGG-S?EE--??TT?----------?S----HH------------------------------------------------HHHHHHHHHHHTT????EEEE?GG--------------GSB-TTB--TT---???TTTS----------?H--------------------HHHHHHHHHHH-HTT?EEEEEE?S---------?EE?--?-----TT?HHHHHHHHTT?-B?---------EETT-EE-----------------?EEEE-TT---------------------EE--------EE?B?T-----TSH-H-HHHHH-HHHHHH----HHHH--------S??S?E-EE?STTT??----------SS?????TT?T----------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTS?SS???GGGTT-??TTTTS?-?TT?EETTTE------------EHHHHGGGHHHHHHHHHHHH--HHT----T?SS???EEESS?BTTGGGT?EE-E??------S?B-SSH------------HHHHH---HHHHHHHHH-HTT??SEE??BT?SBS?-----------??H-----HHHHHH-HHHHTTSSS?EE?-??TT----S???------------------?TTSSHHH---HHHH-----HHHHHHHHHTHHHHHHHHHHHHHH-???SE-E?HHHH?TT-?----GGGTT-??S?EEETT-T---EEEE???-----------------STT-?SEEEEE-E?------SE--E---EEETT------?TT?EE-EESS?--E---EEE--E-E??T--T??EEEEE--TTEEE- 3CTT|A PF01057.12_Parvo_NS1_seed 24 404 !Q:1,43|52,59|63,64|74,74|85,87|106,107|114,114|117,130|132,132|136,136|147,148|167,168|174,198|200,200|211,229|241,245|255,255|258,258|262,262|265,265|267,269|284,285|289,295|299,300|304,307|315,315|318,318|320,320|322,322|325,325|328,328|334,345|355,360|363,366|368,371|380,380|386,393|395,400 Q:0,0|44,51|60,62|65,73|75,84|88,105|108,113|115,116|131,131|133,135|137,146|149,166|169,173|199,199|201,210|230,240|246,254|256,257|259,261|263,264|266,266|270,283|286,288|296,298|301,303|308,314|316,317|319,319|321,321|323,324|326,327|329,333|346,354|361,362|367,367|372,379|381,385|394,394|401,403 T-------------------------------------------TTHHHHHH--------HHT??SHHHHHHHH-HHHHHHHTTT???HHHHHHHHHHHHHHHHHH??THHHHS?SS??------------S?GGG?HHHHHHHHTT??HHHHHHHHHHHHHTTTTT??EEEEE-------------------------S?TTSSHHHHHH-------------------HHHHHSSSEEE?--??TTTTSTTTT?TT?SEE-EE?S???BTTTHHHHHHHHHT??EEE?-----?TTT??EEE????EEEEESS?TT?E-E?SS?EE?TTHHH------------HHTTEEEEE??????TT----S????HHHHHHHH-HHHHH--------T??????SSB 3P0S|A PF01058.17_Oxidored_q6_seed 169 241 !Q:0,0|4,6|13,14|17,17|26,27|29,37|41,41|43,43|46,46|49,49|56,66|75,78|88,92|98,107|125,125|141,143|150,150|153,157|159,199|206,211|215,220|224,224|228,229 Q:1,3|7,12|15,16|18,25|28,28|38,40|42,42|44,45|47,48|50,55|67,74|79,87|93,97|108,124|126,140|144,149|151,152|158,158|200,205|212,214|221,223|225,227|230,240 ?SHH---HHHHHT??SS?HHHHHHHT-?E---------EEE?T-TT?SS?THHHHH-----------HHHHHTTS---?EEEEEESBB---??GGGST----------TBEETTEEHHHHHHHHG-GGSSEEEEEHHHHHH?-?GGGSTT?TT---??B--------------------------------?--------HHHHHG------GGT???---EEE?SSS??HHHHHHHHHHH 3RGW|S PF01060.18_DUF290_seed 60 114 !Q:5,5|8,8|15,15|17,17|25,25|27,31|37,38|45,48|60,66|69,76|78,79|81,82|88,92|96,102|107,108|110,111 Q:0,4|6,7|9,14|16,16|18,24|26,26|32,36|39,44|49,59|67,68|77,77|80,80|83,87|93,95|103,106|109,109|112,113 EEEEE?TT?GGGGSS?E-EEEEEHH-H-----HHTTS??EEEEEE?--?TTSEEEEEEEE???----SS------??S??E--EEEEE?????TTT?--????EEEE??S??TT 3UAF|A PF01063.14_Aminotran_4_seed 78 397 !Q:17,25|27,29|32,32|36,45|55,62|67,70|74,74|80,81|85,85|88,89|93,97|105,108|111,116|123,123|129,129|132,135|140,164|168,168|184,187|191,193|195,195|198,199|201,201|205,205|209,212|223,260|265,279|282,285|289,290|294,298|300,302|310,310|316,316|319,324|328,331|337,337|339,339|341,345|359,361|370,370|374,379|381,382|389,392|397,397 Q:0,16|26,26|30,31|33,35|46,54|63,66|71,73|75,79|82,84|86,87|90,92|98,104|109,110|117,122|124,128|130,131|136,139|165,167|169,183|188,190|194,194|196,197|200,200|202,204|206,208|213,222|261,264|280,281|286,288|291,293|299,299|303,309|311,315|317,318|325,327|332,336|338,338|340,340|346,358|362,369|371,373|380,380|383,388|393,396 ESHHHHHHHHHHHHHHT---------T???SS?HHH----------HHHHHHHHH--------HHTT---?SSE-EEEEE--EEE?SS??STT?????EEEEEEE----EE??????HHHHHH?EEEEE?SS????TTTS------------------------?TTS?BGGGHHHHHHHHHHH----HHT---T?SE--E-EEE?TTS?---EEEESSSEEE--------------------------------------EEET---------------TE----EEE??SSS-----S???HHHHHHH-HHHHH-TT??----EEE????HHHHH-T?S-----EEEEEETTTEEEE---EEEETTEE?TTS------S??HHHHHH----HHHH- 2A1H|A PF01064.18_Activin_recp_seed 26 146 !Q:4,5|9,19|23,23|25,29|35,53|64,64|67,70|77,80|84,84|90,95|100,121|124,125|132,132|141,146 Q:0,3|6,8|20,22|24,24|30,34|54,63|65,66|71,76|81,83|85,89|96,99|122,123|126,131|133,140 EEEE-?SSS---------??TTS?T-----TEEEE-------------------SSEEEEEEEE?TT?---SEEEEE----EEE?STTHH------HHSS?------------------???TT??EEEEEE?SSTTGGGG?????- 3EVS|C PF01065.14_Adeno_hexon_seed 36 613 !Q:1,4|6,8|13,13|16,19|25,26|32,32|37,37|46,46|49,50|66,67|70,70|72,72|76,76|79,79|83,83|86,86|88,88|93,132|139,139|142,142|144,144|149,152|158,158|163,173|176,177|181,181|183,183|186,190|193,195|198,206|215,220|224,226|228,233|237,237|240,241|246,259|264,269|275,279|282,285|289,292|300,304|307,307|315,315|317,317|319,320|322,325|331,331|336,338|340,340|344,344|352,353|355,355|359,360|368,370|372,376|379,380|394,394|398,398|405,410|418,419|421,424|426,427|435,439|443,443|447,447|451,454|457,458|461,461|464,464|466,466|468,472|480,482|485,486|505,505|509,509|511,515|519,530|532,532|542,542|544,545|550,550|557,557|560,561|568,568|575,575|586,586|598,601|607,607|610,610 Q:0,0|5,5|9,12|14,15|20,24|27,31|33,36|38,45|47,48|51,65|68,69|71,71|73,75|77,78|80,82|84,85|87,87|89,92|133,138|140,141|143,143|145,148|153,157|159,162|174,175|178,180|182,182|184,185|191,192|196,197|207,214|221,223|227,227|234,236|238,239|242,245|260,263|270,274|280,281|286,288|293,299|305,306|308,314|316,316|318,318|321,321|326,330|332,335|339,339|341,343|345,351|354,354|356,358|361,367|371,371|377,378|381,393|395,397|399,404|411,417|420,420|425,425|428,434|440,442|444,446|448,450|455,456|459,460|462,463|465,465|467,467|473,479|483,484|487,504|506,508|510,510|516,518|531,531|533,541|543,543|546,549|551,556|558,559|562,567|569,574|576,585|587,597|602,606|608,609|611,612 S????B???SSSB?SS-???SEEEE??SEEEE?SSEE-EEEEEEEE?TT??EEGGGEEEEEEEEEE??TT?B?SBS?SS?TTS?TT?B?SEEE??????????????????????---------?????????EEEEEE?EE?S?EETT----EEEEE?STTS----------?EE??TTT?S?TT??--?SS---SS-----????SSEEEEEE-----?TTS???B------STT?EE??SSTT????????------SSSS??????EEEEE?????SS?---SSS????SEEEEEE???--EE?TTEEEEE?S?S??S--??GGGGG?EEEE???B?EEE?GGGTTTB??S?GGG??EEEETTT???S???-?TT??HHHHHHHHHHHHS?TTS?BGGGTB??????HHHHSEE??B????S??EEEESSS???-?EEE?BEE?SSS---?SS??EE?SS?S?S?----EEEEESS???EE??HHHHHHHHHHHHHTGGGS?GGG?B?---?TTS?--------??-S?TTSHHHHHH?B??GGGG?TTTTTT?EE??HHHHTS?TTSSTT?HHHHHHHHHH?SSSEEEEEEEE????TTTTT?EE?SE 2OBE|A PF01067.17_Calpain_III_seed 91 277 !Q:0,4|14,20|24,26|28,30|34,34|37,45|51,65|69,83|85,86|88,91|94,114|116,119|125,134|139,155|158,159|162,171|173,173|175,185|193,211|213,227|237,237|241,241|245,246|257,259|263,263|272,273 Q:5,13|21,23|27,27|31,33|35,36|46,50|66,68|84,84|87,87|92,93|115,115|120,124|135,138|156,157|160,161|172,172|174,174|186,192|212,212|228,236|238,240|242,244|247,256|260,262|264,271|274,276 ??---EEEEEEEEE-?-----TTT---T???STT?TT---------TGGGS?-------------?EEE---------------E??S????SS?------------------?-S?--?EEEEE----------EEEE--------------???TT??ST----------T?S???--------EEEEEEE???--??????????????S???---?????????BSSSEEEEE-EEE?SSE--EEEEEEESSS???EEE-EEEEEESS??EEE 1U5I|A PF01068.16_DNA_ligase_A_M_seed 46 300 !Q:0,1|8,9|20,37|40,40|52,53|58,59|61,61|65,65|70,70|74,74|76,76|79,86|88,88|97,97|101,101|104,108|118,119|121,121|125,125|128,129|137,138|141,161|165,168|182,190|195,203|207,207|220,237|245,246|249,252|277,277|281,281|284,284|287,288|290,291 Q:2,7|10,19|38,39|41,51|54,57|60,60|62,64|66,69|71,73|75,75|77,78|87,87|89,96|98,100|102,103|109,117|120,120|122,124|126,127|130,136|139,140|162,164|169,181|191,194|204,206|208,219|238,244|247,248|253,276|278,280|282,283|285,286|289,289|292,299 ??EEEEES--SHHHHHHHTT------------------TS?EEEEEEESSEE--EEEE--E?TTS?EEEE?TTS?B?TT--------T?HHHHHTSG-GGB?TT???--EEEEEEEEE--E?TTT?SB??HHHHTTS?-SS??----------?--------GGG?--?SEEEEEEEEEEEE---------TTEE-?-------TTS?HHHHHHHHHHHB----------------??BTTTEEE??EE????HHHHHHHHHHHHHTSEEEEEEEES-SSS?SS?TT--T?-SEEEEEEE 1VS0|A PF01070.13_FMN_dh_seed 180 617 !Q:1,1|6,6|9,10|17,18|22,22|28,28|39,42|44,48|50,52|54,56|58,61|66,70|81,83|85,85|90,90|92,92|94,95|99,102|106,106|114,117|121,121|124,124|127,127|129,133|137,142|145,145|147,172|174,175|180,181|183,184|186,186|197,197|200,201|205,206|212,212|214,214|217,220|222,223|230,241|244,251|256,291|294,362|370,370|373,381|384,386|388,388|391,391|398,399|401,405|407,407|412,417|430,432|434,434|439,440|446,472|476,478|487,487|490,491|494,494|496,526|529,533|535,535|542,543|556,556|558,558|562,562|571,571|598,598|604,608|610,610|613,613 Q:0,0|2,5|7,8|11,16|19,21|23,27|29,38|43,43|49,49|53,53|57,57|62,65|71,80|84,84|86,89|91,91|93,93|96,98|103,105|107,113|118,120|122,123|125,126|128,128|134,136|143,144|146,146|173,173|176,179|182,182|185,185|187,196|198,199|202,204|207,211|213,213|215,216|221,221|224,229|242,243|252,255|292,293|363,369|371,372|382,383|387,387|389,390|392,397|400,400|406,406|408,411|418,429|433,433|435,438|441,445|473,475|479,486|488,489|492,493|495,495|527,528|534,534|536,541|544,555|557,557|559,561|563,570|572,597|599,603|609,609|611,612|614,616 H-HHHS?HH--HHHHHH??STT?HHHHH-HHHGGGGEEE????S--???S---S?--B??--EEET-----TEEESSSEEE???S?GGGT?T-T--THH----HHH-HHHHHHT?--?EEE?TT?SS?H-----HHH------HH-T--------------??--------??E--EEEE??B--S?HHHHHHHHHH-HH--HTT??EEEEE?S?SS????H--HHHHHT?----??----?TT?-?----?TTTT------------------------------------TS?---------------------------------------------------------???????????HHHHHHH-TB---?-----TT-??H-HH-HHHHHT--T-?--?S?EEEE??---?SHHHHHHHHHTT--?S-EEEE??GGGTS---------------------------STT???HHHHHHHH-HH--HH-T-------------------------------TS-----S?EEEESS??SHHHHHHHHHTT?S?EEE?HHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHT?SBGGG?---?G-GG-EEE 1MEI|A PF01071.14_GARS_A_seed 19 249 !Q:14,15|17,19|25,26|28,28|39,39|42,42|44,47|55,60|64,68|84,94|100,102|113,113|116,116|120,122|135,165|177,180|182,182|185,186|210,213|224,224|228,233|243,244 Q:0,13|16,16|20,24|27,27|29,38|40,41|43,43|48,54|61,63|69,83|95,99|103,112|114,115|117,119|123,134|166,176|181,181|183,184|187,209|214,223|225,227|234,242|245,248 HBHHHHHHHHHHTT??B?-?EEEES--S-HHHHHHHHHH?SS?E----EEEEESB??????EEE?----SSHHHHHHHHHHHTT?????-?????EEEEE???SEEEEEEEEE?SS?EEE???BEEEEEEETTTE-------------------------------EEEEEEEEEEE----S?TT??HHHHHHHHHHTHHHHHHHHHHTT????EEEEEEEEEE-TTE------EEEEEEESS??TTTH 2YS7|A PF01073.14_3Beta_HSD_seed 12 306 !Q:21,24|30,39|42,43|46,46|49,49|51,51|53,58|61,63|66,66|78,78|83,84|86,88|92,93|97,97|102,103|123,123|137,142|145,146|148,148|152,160|174,174|180,184|188,190|197,197|201,201|219,220|227,229|232,232|250,251|254,267|272,272|274,275|278,278|292,295|297,299|303,305 Q:0,20|25,29|40,41|44,45|47,48|50,50|52,52|59,60|64,65|67,77|79,82|85,85|89,91|94,96|98,101|104,122|124,136|143,144|147,147|149,151|161,173|175,179|185,187|191,196|198,200|202,218|221,226|230,231|233,249|252,253|268,271|273,273|276,277|279,291|296,296|300,302 EEETTTSHHHHHHHHHHHTTT---?EEEEE?-------??SS??GG-GS?T-T??----EE???TT?HHHHHHHHHHH?EEEE??S???HHH--HHH?HHHH--HHHHTHHHHHHHHHHHHTT?SEEEEEEEHHHHH?--???TT??B?TTS?--??--??SHHHHHHHHHHHH-HHHHH-----HHH???EEEEEE?EEE?TSTTHHHHHHHHHHHHT??EEEETS???EE?EEEHHHHHHHHHHHHHH??EE--------------EEES?S??EE-HHHHHHHHHHHHT????E---EEE??? 1Z7E|A PF01074.17_Glyco_hydro_38_seed 50 393 !Q:9,10|16,16|21,28|37,38|43,45|52,52|55,56|58,59|62,63|74,74|76,76|97,98|101,101|103,103|107,108|128,134|139,140|145,145|154,154|158,159|164,167|176,183|187,187|193,194|197,197|200,205|208,208|214,215|218,218|228,228|232,237|242,242|245,245|251,253|255,255|258,264|288,293|306,306|308,308|329,329|331,331|333,333|336,341|347,348|350,350|363,374|378,381|384,384|387,387|389,389|391,391 Q:0,8|11,15|17,20|29,36|39,42|46,51|53,54|57,57|60,61|64,73|75,75|77,96|99,100|102,102|104,106|109,127|135,138|141,144|146,153|155,157|160,163|168,175|184,186|188,192|195,196|198,199|206,207|209,213|216,217|219,227|229,231|238,241|243,244|246,250|254,254|256,257|265,287|294,305|307,307|309,328|330,330|332,332|334,335|342,346|349,349|351,362|375,377|382,383|385,386|388,388|390,390|392,392 EEEEEEEEE??SSSSS?HHHH--------HHHTHHHH--HHHH---HHHHHH?TT??E--EE??HHHHHHHHTT-S?HHHHHHHHHHHHTTSEEESS??SS?B?SSS??HHHHHHHHHHHHHHHHHHT?--????EEEE??SSSB?THHHHHHH-TTT??EEEE????HHHHHHHH--------HTT?SEEEE??TT?SS-----?TT?EEEEE??SS?SSGGGTSSS?HHH------HGGG?TT?SSTTS???T-TS???????TTTHHHHHHHHHHHHHHHHTTSS------SSEEEEEEEEET?S?SHHHHHHHHHHHHHHHHHHH-H?G-GG-----?EEEEE??H-HHHHHHHHHHHH------------TTS????EE-ES?B?S?B 1HTY|A PF01075.12_Glyco_transf_9_seed 18 287 !Q:12,13|19,19|21,22|34,34|41,41|45,48|52,52|57,59|63,65|77,77|81,81|88,88|91,99|112,122|126,126|132,134|137,140|145,146|162,164|169,171|186,186|193,198|202,202|207,207|237,238|247,247|252,259|268,268|270,286 Q:0,11|14,18|20,20|23,33|35,40|42,44|49,51|53,56|60,62|66,76|78,80|82,87|89,90|100,111|123,125|127,131|135,136|141,144|147,161|165,168|172,185|187,192|199,201|203,206|208,236|239,246|248,251|260,267|269,269 HHHHHHHTTTTT-?SEEEE?S??SGGGHHHHHTT?SEEEEE?TTT?---TTT?TEEE???TTT-??SHHHHHHHTTS?GGG?SSGGGS?SS?????????HHHHHHHHHHTT---------??SSS?EEEEE???TT?---GGGS??HHHHHHHHHHHHHTT--?EEEE???GGGHHHHHHHHTTS?HHHHTT------EEE?TTTS?HHHHHHHHHTSSEEEEESSHHHHHHHHTT??EEEEESSS?TTSS?----???TTEEEEES-S??-?????????????? 2GT1|A PF01077.17_NIR_SIR_seed 91 312 !Q:0,0|5,7|10,11|16,16|19,19|22,22|24,48|57,74|84,85|89,89|91,91|97,105|109,109|112,112|117,117|128,129|132,132|145,145|155,157|159,160|169,171|174,175|186,186|190,193|200,200|206,207|217,218|220,220|225,226|228,229|234,237|241,245|248,248|264,271|274,275|278,282|291,293|302,302|304,307 Q:1,4|8,9|12,15|17,18|20,21|23,23|49,56|75,83|86,88|90,90|92,96|106,108|110,111|113,116|118,127|130,131|133,144|146,154|158,158|161,168|172,173|176,185|187,189|194,199|201,205|208,216|219,219|221,224|227,227|230,233|238,240|246,247|249,263|272,273|276,277|283,290|294,301|303,303|308,311 ?SSSB???EE??GGGS?TT?SS?H-------------------------HHHHHHHH------------------HHTHHHHHS??SSS?B?EEEES---------STT?TT?HHHH?SEEEEEEESS??EE?HHHHHHHHTTSS?GGGGTTTTS???S??HHHHTTTT?--TT??EEEETTEEEE?GGG????SHHHHH?TTTEE??SSEEEEEEE??B?STTT??B??EEEE----EEE???--TT?HHHHHHHHHHHHHHH--------HH??TT?---?HHHHHHHH--?HHHHHHHT-T????GGGB 3MMC|A PF01078.16_Mg_chelatase_seed 56 215 !Q:0,0|5,5|7,7|20,23|28,29|33,33|46,47|57,59|61,63|65,66|70,72|77,77|80,86|92,92|96,96|102,103|122,122|141,142|145,146|148,148|152,153|161,161|163,169|171,174|177,194|199,199|205,212 Q:1,4|6,6|8,19|24,27|30,32|34,45|48,56|60,60|64,64|67,69|73,76|78,79|87,91|93,95|97,101|104,121|123,140|143,144|147,147|149,151|154,160|162,162|170,170|175,176|195,198|200,204|213,214 -GGGS?S?HHHHHHHHHHHG??--EEEE??GGG?TTHHHHHHHHHS??EESGGGSTT???S???E--EEE???EEEE?TT-----??HHHHH?EHH?GGGEE??HHHHHTTEEEEETTGGGS?HHHHHHHHHHHHHSEEEE??TT??E-EEE??EEEEEEE?S------?S????HH------------------HHTT?SEEEE?---????SH 4FDG|A PF01079.15_Hint_seed 46 341 !Q:0,19|21,21|24,24|32,32|39,40|43,43|48,50|52,53|57,57|72,77|92,93|98,98|101,101|110,125|130,153|161,162|165,165|170,176|178,178|182,183|195,195|221,340 Q:20,20|22,23|25,31|33,38|41,42|44,47|51,51|54,56|58,71|78,91|94,97|99,100|102,109|126,129|154,160|163,164|166,169|177,177|179,181|184,194|196,220 -------------------?B?TT?EEEBTTS?EEEGGG??TT?EEEE---E?-TTS?EEEEEEEEEEEEEE------EEEEEEEEEEETTS-?EEEE?TT?EEEEEETT----------------TTEE------------------------EEEEGGG??TT?EEEE-------E?TTT??EEEEEEEEEEE-EEEEEEEEEEESSSEEEETTEEEES??---------------------------------------------------------------------------------------------------------------------- 2JMZ|A PF01080.12_Presenilin_seed 6 480 !Q:0,230|237,242|245,246|249,253|256,256|258,289|291,323|325,329|331,345|349,349|351,355|357,357|370,373|377,382|384,396|399,400|403,403|422,423|451,451|453,453|459,462|475,476 Q:231,236|243,244|247,248|254,255|257,257|290,290|324,324|330,330|346,348|350,350|356,356|358,369|374,376|383,383|397,398|401,402|404,421|424,450|452,452|454,458|463,474|477,479 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?HHHHHH------HT??TT?????TT-S-------------------------------?S????------??????-????????????????S-----S---------------SSS?S?????S?THHHHHHHHHHH----HHT??----S?----------??SS??SS?TTTHHHHHHHHHHHHHHS??TTTTHHHHHHHHHHHHHHHHHHHHHHT?S?SSSSS????HHHHHHHHTTTT??GGG 2KR6|A PF01081.14_Aldolase_seed 5 196 !Q:7,7|14,16|33,34|41,41|56,56|65,67|80,80|82,82|88,89|102,102|121,122|145,145|148,148|156,157|171,172|180,180|188,188|196,196 Q:0,6|8,13|17,32|35,40|42,55|57,64|68,79|81,81|83,87|90,101|103,120|123,144|146,147|149,155|158,170|173,179|181,187|189,195 HHHHHHS?SEEEEE???SGGGHHHHHHHHHHTT??EEEEES?STTHHHHHHHHHHH?TTSEEEEE???SHHHHHHHHHHT?S?EEESS??HHHHHHHHHSSS?EEEEESSHHHHHHHHHTT??EEEETTTTTTTHHHHHHHHHTT?TT?EEEEBSS??TTTHHHHHTSTTB??EEESTTS?HHHHHHT?HHHHHHH- 1FQ0|A PF01082.15_Cu2_monooxygen_seed 38 174 !Q:7,8|11,15|17,17|20,20|28,28|30,30|32,34|36,36|45,56|67,73|76,77|81,93|99,110|114,117|119,120|131,137|149,149|151,151|162,166|169,170|172,173 Q:0,6|9,10|16,16|18,19|21,27|29,29|31,31|35,35|37,44|57,66|74,75|78,80|94,98|111,113|118,118|121,130|138,148|150,150|152,161|167,168|171,171 EEEEEEE??SB--???S-TT?EEEEEEE?S?S---S?EEEEEEEE????------??EEEEEEEEES------?BS??SSS-------------EEGGG-----------?SBS----S??EEEEEEESSS?????-?TTEEEEESTTT-S-BSEEEEEEEE??-??TT??S?? 1YJL|A PF01083.17_Cutinase_seed 23 243 !Q:0,3|11,12|15,16|19,22|44,50|52,54|57,57|63,64|87,87|110,110|112,112|119,121|123,124|126,126|141,141|144,152|156,156|161,163|166,167|170,170|173,175|177,180|182,184|190,191|196,197|200,200|204,205|208,210|214,217|220,222|227,227|229,229|241,242 Q:4,10|13,14|17,18|23,43|51,51|55,56|58,62|65,86|88,109|111,111|113,118|122,122|125,125|127,140|142,143|153,155|157,160|164,165|168,169|171,172|176,176|181,181|185,189|192,195|198,199|201,203|206,207|211,213|218,219|223,226|228,228|230,240 --??SEEEEEE??TT??SS?---GGGHHHHHHHHHHSTTEEEEE??-----S???SS?GGGTT??HHHHHHHHHHHHHHHHHHHHHH?TTSEEEEEEETHHHHHHHHHHH?S?BGGGTB???S??S?HHHHHHEEEEEEES?TT?--------BTT?TTEE---SS??SB?TT???T----T???TTGGG--EEEE??TT?SSS--SS???HHH----HH--?HHHH-H-HHHHHHHHHHH?? 1UZA|A PF01084.15_Ribosomal_S18_seed 121 63 !Q:0,12|14,14|16,16|25,25|27,27|30,30|32,33|38,39|41,42 Q:13,13|15,15|17,24|26,26|28,29|31,31|34,37|40,40|43,62 ?????-???----T-T?HHHHGGGB?S-SS?B??HHHH--T??HHHHHHHHHHHHHHHTTTSS 3KIX|r PF01085.13_HH_signal_seed 4 163 !Q:0,21|24,24|30,30|38,45|54,54|57,59|65,66|77,77|98,99|107,108|110,111|113,113|116,116|122,122|131,132|148,148 Q:22,23|25,29|31,37|46,53|55,56|60,64|67,76|78,97|100,106|109,109|112,112|114,115|117,121|123,130|133,147|149,162 ?????--???????????????TT?EESSS?TTSTTTT????????TTSSGGGG?EE???TTEEE??TTSSSGGGEE?HHHHHHHHHHHHHHHHHSTT??EEEEESS??S??S?TT?GGGGT?EEEEEETT??GGGHHHHHHHHHHTT?SEEEEEETTEEEEE 3M1N|A PF01086.12_Clathrin_lg_ch_seed 28 290 !Q:0,140|147,148|204,204|219,222|227,230|237,240|242,256|259,259|261,261|263,289 Q:141,146|149,203|205,218|223,226|231,236|241,241|257,258|260,260|262,262 ??--????????????----------???????????????????????------????---?--????????------------------?????????????????--------?????????????????????????STTTBS--TTHHHHHHHHHTTTSTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?SSTTTSSHHHHHHH????TTTH----HHHHHH???-T---------------TT?S?T--------------------------- 1XI4|J PF01087.17_GalP_UDP_transf_seed 135 362 !Q:0,4|9,48|62,75|77,77|81,97|99,99|101,117|119,126|129,129|135,135|137,137|139,142|145,146|148,153|156,156|161,161|164,164|166,167|169,196|198,207|210,210|214,215|217,217|224,225|227,227|230,232|237,237|239,244|261,267|271,293|295,295|310,316|318,319|321,350|360,361 Q:5,8|49,61|76,76|78,80|98,98|100,100|118,118|127,128|130,134|136,136|138,138|143,144|147,147|154,155|157,160|162,163|165,165|168,168|197,197|208,209|211,213|216,216|218,223|226,226|228,229|233,236|238,238|245,260|268,270|294,294|296,309|317,317|320,320|351,359 ?-???TTTS---------------------------------------?EEEEETTTTEEEE--------------E?GGG-----------------G?S--???????????????S??------TT?TTSTT?B?T----TS?-B????--SS?EEEE?TT?S??S-???????----------???-------S----------SS?EEE??E-EEEEEE??S?TT-??GGGS?H------HHHHHHHHHHHHHHHH-------HTT-----------------------T?SEEEEEEEESGGGT?------S??S?-----------------------------EEEEEEESS?? 1GUP|A PF01088.16_Peptidase_C12_seed 72 291 !Q:1,4|6,7|9,10|23,23|26,26|32,34|36,36|39,41|48,48|50,50|60,64|80,88|91,95|98,106|110,110|123,124|129,136|138,138|141,141|154,155|157,157|167,171|183,187|189,189|191,201|204,211|215,223|232,236|245,247|252,252|254,254|260,268|278,279|284,284 Q:0,0|5,5|8,8|11,22|24,25|27,31|35,35|37,38|42,47|49,49|51,59|65,79|89,90|96,97|107,109|111,122|125,128|137,137|139,140|142,153|156,156|158,166|172,182|188,188|190,190|202,203|212,214|224,231|237,244|248,251|253,253|255,259|269,277|280,283|285,290 B????B??H--HHHHHHHHHTTB?TT-EEEEE???S-SH---HHHTTS?S?EEEEEEEEE??---HHHHHHHHHHHHHHH---------HH?????TT??????--?SBT?HHHHHHHHHHHT--TGGG-??-----B?TT?HHHHHHHHHTTS-?H-HHHHHHHHT?----HHHHHHHHHHH-----T?S-----------SS????----TTS??------?EEEEEEEE-----ETTEEEEE?--TTSS-S?EEEEE??-------TTTHHHHHH--HHHH-HHHHHS 3TB3|A PF01090.14_Ribosomal_S19e_seed 62 153 !Q:0,1|6,6|22,23|26,28|35,36|39,40|43,47|50,50|68,68|70,71|80,81|84,87|89,90|93,94|97,100|119,120|122,126|130,130|133,133 Q:2,5|7,21|24,25|29,34|37,38|41,42|48,49|51,67|69,69|72,79|82,83|88,88|91,92|95,96|101,118|121,121|127,129|131,132|134,152 ??GGGS?HHHHHHHHHHHHHHS-?SS???THHHHT??SS??SS????-HH-HHHHHHHHHHHHHHHSS-S??HHHHHHHT??EE?--?T--TS??EE????HHHHHHHHHHHHHHTSEE??T-----TTS?EE?HHHHHHHHHHHHHHHHHHH 3JYV|T PF01091.13_PTN_MK_C_seed 10 66 !Q:1,3|7,14|29,30|34,36|45,46|49,53|56,65 Q:0,0|4,6|15,28|31,33|37,44|47,48|54,55 S???EEE????????TTTSEEEEEEEEEE??SSS???SSEEEEEE??SS?-???SS?????????? 2LUU|A PF01092.14_Ribosomal_S6e_seed 7 127 !Q:0,0|17,19|29,30|33,33|41,41|47,47|56,56|59,61|63,63|66,68|77,77|84,85|90,91|98,98|101,102|105,105|115,116|119,120 Q:1,16|20,28|31,32|34,40|42,46|48,55|57,58|62,62|64,65|69,76|78,83|86,89|92,97|99,100|103,104|106,114|117,118|121,126 ?EEEEEETTTTEEEEEE???HHHHHTTTT??TT?EEETTTT?SSSSS?EEEEEEEE?TT???B?TT???SSEEEEEE?TTBTTB??SSTT??EEEEEE?SS??TT?SEEEEEEEE??SS??HHHHTS 2XZM|Y PF01094.23_ANF_receptor_seed 119 662 !Q:15,15|18,18|21,23|26,27|35,35|38,38|48,51|58,86|92,95|100,100|113,114|116,118|123,147|149,152|157,160|164,165|172,173|176,177|182,182|193,210|213,215|226,228|233,239|251,251|253,255|259,267|272,279|292,292|296,297|303,304|309,314|322,329|334,334|339,339|344,344|350,350|352,387|393,393|400,400|407,410|420,421|425,426|428,428|441,488|494,495|498,501|526,530|533,595|602,602|608,608|614,626|628,634|636,636|640,640|643,645|650,653|661,661 Q:0,14|16,17|19,20|24,25|28,34|36,37|39,47|52,57|87,91|96,99|101,112|115,115|119,122|148,148|153,156|161,163|166,171|174,175|178,181|183,192|211,212|216,225|229,232|240,250|252,252|256,258|268,271|280,291|293,295|298,302|305,308|315,321|330,333|335,338|340,343|345,349|351,351|388,392|394,399|401,406|411,419|422,424|427,427|429,440|489,493|496,497|502,525|531,532|596,601|603,607|609,613|627,627|635,635|637,639|641,642|646,649|654,660 HHHHHHHHHHHHHHH?SS-SS---SS??EEEEEEE?TT?HHHHHHHGG----GGGGGG???????????-----??????-??????EEEEE--??SSHH-HHHHHTTHHHHT--T?-?EEES-------------------------S-???GGGG?---TTT--TSSEEE--SS??HHHH-HHHHHHHHHH------------------TT???EEEEEESSHH---HHHH-------HHHHHHHHHHT-T???EEE---------EEEE????????HHHHHHHHHHTT-STT??EEEEE??HHHH------HHHHHHH--------HHTT?TTTS-EEEE?TTTTT?S------------------------------------GGGSS?HHHHTT?EEEEES????HHHHHHHTT??TTT??S?TTHHHHHHHHTT?---------------??-?????????-------------???????SGGGG??SS????TTHHHHHHHHHHHHHHHHHHHHHH?????SS--------------------------------------------------------------?TTTTTT?HHHHH-HHHTT-----------??E-------E?TTS?EE???TTSB????EEEEEEE? 3Q41|A PF01095.14_Pectinesterase_seed 35 318 !Q:4,4|8,8|22,23|26,26|29,32|38,38|43,43|45,47|51,51|54,55|63,63|72,75|80,82|87,87|92,92|96,96|106,108|112,115|120,121|133,133|137,137|141,141|150,150|158,158|163,163|170,170|175,181|185,187|194,196|200,202|209,209|214,214|219,222|229,229|234,235|240,240|247,247|250,250|254,254|257,260|264,265|272,272|279,279|285,286|289,292|298,300|314,314 Q:0,3|5,7|9,21|24,25|27,28|33,37|39,42|44,44|48,50|52,53|56,62|64,71|76,79|83,86|88,91|93,95|97,105|109,111|116,119|122,132|134,136|138,140|142,149|151,157|159,162|164,169|171,174|182,184|188,193|197,199|203,208|210,213|215,218|223,228|230,233|236,239|241,246|248,249|251,253|255,256|261,263|266,271|273,278|280,284|287,288|293,297|301,313|315,317 SEEE?TTS?SSBSSHHHHHHHS?-SS?SS?---EEEEE?SEEE-E?-?EEE?TT??SEEEEES?TTTEEEEE-???TTTT?-?TGGG?SEEE?STT?EEEEEEEEE???GGG????SEEE??TTEEEEEEEEE?STT?EEE?SSEEEEES?EEEESSS?EEES?EEEEES?EEEE----???STT?-?EEEEEE???STT???EEEEES?EEEE?TTTG----GGGGGS?EEEE??SSTT?EEEEES?EE?TTB?TT????SST--TTTTTT?EEEEES?BSGGG??TT????TTEEE???HHHHHTTSHHHHS?GGG 2NTB|A PF01096.13_TFIIS_C_seed 109 46 !Q:0,2|4,4|6,8|10,11|18,18|21,22|27,27|37,38|41,42|46,46 Q:3,3|5,5|9,9|12,17|19,20|23,26|28,36|39,40|43,45 ???T-T---T??SEEEEE-EE??SSSS?SSEEEEEES--SS??EEE- 1K83|I PF01097.13_Defensin_2_seed 15 38 !Q:0,0|4,6|18,18|20,24|27,27|29,30|33,37 Q:1,3|7,17|19,19|25,26|28,28|31,32 ?SSS???TTTHHHHHHHT-T-????SS?S--SS????? 2E3F|A PF01099.12_Uteroglobin_seed 32 75 !Q:0,0|14,16|28,30|48,49|67,71 Q:1,13|17,27|31,47|50,66|72,74 ?HHHHHHHHHHHHS--?HHHHHHHHHTT???HHHHHHHHHHHHHHHHH??HHHHHHHHHHHHHHHTS-----HHH 1CCD|A PF01102.13_Glycophorin_A_seed 5 151 !Q:2,2|10,13|15,21|26,26|29,33|36,43|46,48|57,60|65,66|103,150 Q:0,1|3,9|14,14|22,25|27,28|34,35|44,45|49,56|61,64|67,102 HH-HHHHHHH----H?------SSSS?TT?????SS--------SS???HHHHHHHH----HHHH--HHHHHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHH????????---??--------------??---------------???? 2KPF|A PF01103.18_Bac_surface_Ag_seed 70 651 !Q:14,27|29,42|44,44|57,59|65,81|93,125|127,128|133,133|135,136|150,155|157,163|170,174|186,189|200,222|225,229|231,250|252,253|255,255|257,257|261,262|273,274|279,279|281,282|287,298|307,330|333,333|336,338|347,347|356,357|359,359|364,370|381,381|383,383|385,402|404,408|412,412|414,414|416,416|418,427|435,435|438,438|441,441|446,467|470,470|472,472|479,480|494,495|498,499|505,505|507,507|519,532|535,535|543,544|547,547|551,552|554,574|576,576|579,580|594,594|605,605|608,611|613,614|617,636|639,640|647,647|650,650 Q:0,13|28,28|43,43|45,56|60,64|82,92|126,126|129,132|134,134|137,149|156,156|164,169|175,185|190,199|223,224|230,230|251,251|254,254|256,256|258,260|263,272|275,278|280,280|283,286|299,306|331,332|334,335|339,346|348,355|358,358|360,363|371,380|382,382|384,384|403,403|409,411|413,413|415,415|417,417|428,434|436,437|439,440|442,445|468,469|471,471|473,478|481,493|496,497|500,504|506,506|508,518|533,534|536,542|545,546|548,550|553,553|575,575|577,578|581,593|595,604|606,607|612,612|615,616|637,638|641,646|648,649 EETTTTEEEEEEEE--------------E?-------------S-SEEEEEEEEEEE---EESTT---------------??EEEEEEEEEEE---------------------------------E??SSSS?S??EEEEEEEEEEEEE?----?S-------SSEEEE-----EEEEEEEEEEE????BHHHHHHHHH-----------------------TT?-???T--------------------T??S?S?EEE??EEEEEEEEEE??SSSS-S??SEEE------------EEEEEEEE---------------------?--TT?SS?--EEEEEEEE-EEEEESSS--S?SSEE-------EEEEEEEEEE-E?S------------------S??-??GGG?B?B?B----------TTTBTEE?TT?BS?EEEE??--------------------SS?S?EEEEEE??BSEEEEEEEEEEE??SS??STTST-T-EEEEEEEEEEE--------------EE?TTGGGGS--TT?TTS??T---------------------T?TT??EEEEEEEEEEEET-TEEEEEEEEE-EE----E??TT-??-----------------EE-?EEEEEE-EE? 4K3C|A PF01106.12_NifU_seed 20 74 !Q:7,7|17,17|24,25|28,31|41,42|45,45|65,65|67,68 Q:0,6|8,16|18,23|26,27|32,40|43,44|46,64|66,66|69,73 HHHHHHH-HHHHHHHHS?EEEEEE??SS----EEEEEEESS??SS?HHHHHHHHHHHHHHHHHST-T??EEEEE 2Z51|A PF01108.12_Tissue_fac_seed 59 168 !Q:0,32|34,39|56,68|76,81|85,85|87,112|114,114|118,119|121,124|130,132|137,137|142,142|144,147|151,151|165,167 Q:33,33|40,55|69,75|82,84|86,86|113,113|115,117|120,120|125,129|133,136|138,141|143,143|148,150|152,164 ----------------------???????????E------EEEEEEETTEEEEEEE?---?????????EEEEEEE------ETT?S--------------------------S?EEE--E----EEEEE??-SEEE?TGGG?S----TTS?EEEEEEEEETTEE??? 2KZ1|B PF01109.12_GM_CSF_seed 7 124 !Q:0,6|10,11|18,18|29,32|38,39|47,49|53,54|67,68|90,94|97,98|119,119|122,123 Q:7,9|12,17|19,28|33,37|40,46|50,52|55,66|69,89|95,96|99,118|120,121 ???????TTT??HHHHHH-HHHHHHHHHH????HHHHT?-EEEEESS???TTS??SHHHHHHHHHHT??GGGGGGHHHHHHHHHHHHHHS?????SS??EEEEEHHHHHHHHHHHHTTS?SS?? 2GMF|A PF01110.12_CNTF_seed 2 200 !Q:0,11|14,14|44,68|102,102|132,137|141,151|183,184|186,199 Q:12,13|15,43|69,101|103,131|138,140|152,182|185,185 ????????????HH-HHHHHHHHHHHHHHHHHHHHHHHHHHHTT?????????????????????????HHHHHHHHHHHHHHHHHHHHHHHHHHHTTTSSS?SHHHHHHHHHHHHHHHHHHHHHHHHHHTT??????SSS???????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??S??------------ 1CNT|1 PF01111.14_CKS_seed 33 89 !Q:0,1|5,6|9,9|12,12|20,21|29,29|32,41|43,45|49,49|55,65|68,68|73,74|77,77|87,87 Q:2,4|7,8|10,11|13,19|22,28|30,31|42,42|46,48|50,54|66,67|69,72|75,76|78,86|88,88 ??EEE??EE?SS-EEEEEEE??GGGGGGS?SS----------S???HHH-HHHHT-------????TT?EEEE??SS?TTEEEEEEE?S 3QY2|A PF01112.13_Asparaginase_2_seed 7 365 !Q:0,2|6,6|10,11|15,17|20,24|26,27|53,54|71,71|79,81|86,88|110,110|112,112|126,126|143,147|152,153|168,171|174,217|224,224|228,228|236,238|242,242|247,247|259,259|270,270|291,295|312,316|318,319|329,330|333,334|350,351|357,364 Q:3,5|7,9|12,14|18,19|25,25|28,52|55,70|72,78|82,85|89,109|111,111|113,125|127,142|148,151|154,167|172,173|218,223|225,227|229,235|239,241|243,246|248,258|260,269|271,290|296,311|317,317|320,328|331,332|335,349|352,356 ???EEE-EEE--EEE???GG-----G??HHHHHHHHHHHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHST-TSSSSTT???BTTS???EEEEEEETTTTEEEEEEEESS?S?HHHHHHHHHHHSS?SEEEHHHHHHHHHHTT?????GGGG??HHHHHHHHHHHHHH----HH???????----------------???????-----------???EEEEEE?TTS?EEEEEEE???TTB?TTEE?STTSBTTTEEE?TTSEEEEEEE?HHHHHHTTHHHHHHHHHHTT?--??HHHHHHHHHHTHHHHT-----T??EEEEEEETT??EE??BSSSEEEEEEEETTS??EEEEE????--?? 2ZAK|A PF01113.15_DapB_N_seed 99 167 !Q:22,22|24,29|38,40|43,44|46,48|54,61|67,70|72,72|74,77|79,79|87,89|91,100|105,105|107,108|123,123|125,125|130,138|148,148|151,153|156,157|163,163|165,166 Q:0,21|23,23|30,37|41,42|45,45|49,53|62,66|71,71|73,73|78,78|80,86|90,90|101,104|106,106|109,122|124,124|126,129|139,147|149,150|154,155|158,162|164,164 EEEEETTTTSHHHHHHHHHHHS-S------TTEEEEEE???TT--S???SBIII--------IITSS?-??S?B??--S?SGGGTTS--?S----------EEEE?S-?HHHHHHHHHHHHHT-T?EEEE?????---?HHHHHHHHH-HT---TT--SEEEE?S?? 3UPY|A PF01114.13_Colipase_seed 9 40 !Q:0,8|13,13|22,23|26,27|31,33|36,38 Q:9,12|14,21|24,25|28,30|34,35|39,39 ?????????TTSB?SSTTSSSS??EE??SSS???EE???B 1PCO|A PF01115.12_F_actin_cap_B_seed 31 378 !Q:6,7|14,14|28,28|30,30|32,43|53,57|62,62|68,69|75,75|86,86|90,91|95,96|98,114|116,120|145,145|148,155|166,188|200,242|262,262|266,275|293,304|307,307|309,313|316,316|333,333|337,343|345,345 Q:0,5|8,13|15,27|29,29|31,31|44,52|58,61|63,67|70,74|76,85|87,89|92,94|97,97|115,115|121,144|146,147|156,165|189,199|243,261|263,265|276,292|305,306|308,308|314,315|317,332|334,336|344,344|346,377 HHHHHH--HHHTTS?GGGHHHHHHHHHH-H?G------------GGHHHHHHH?????EEEE-ETTTT--EEEEE?GGGEETTEEE?TTT??EES??S-----------------S?????HHHHHHHHHHHHHHHHHHHHHHSS-SE--------EEEEEEEETT-----------------------EEEEEEEEEEE-----------------------------------------??TTSSEEEEEEEEEEEEEEE?TTS----------SEEEEEEEEEEEEEEEE------------SS?S-----TT?EEEEEEEEEEEEEEEE?BTT-------B?HHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHH 3LK2|B PF01116.15_F_bP_aldolase_seed 188 528 !Q:0,0|3,3|16,17|23,24|41,42|47,48|53,53|57,73|75,76|90,91|93,99|101,102|107,108|111,111|113,118|129,136|138,139|143,149|152,153|155,161|164,165|185,187|189,191|198,212|215,215|218,220|224,234|239,240|252,253|256,261|264,264|267,268|271,272|275,283|287,298|301,302|304,338|346,371|373,381|385,385|387,401|413,416|418,418|420,422|440,440|452,471|478,478|481,495|517,518|521,521|523,523|526,527 Q:1,2|4,15|18,22|25,40|43,46|49,52|54,56|74,74|77,89|92,92|100,100|103,106|109,110|112,112|119,128|137,137|140,142|150,151|154,154|162,163|166,184|188,188|192,197|213,214|216,217|221,223|235,238|241,251|254,255|262,263|265,266|269,270|273,274|284,286|299,300|303,303|339,345|372,372|382,384|386,386|402,412|417,417|419,419|423,439|441,451|472,477|479,480|496,516|519,520|522,522|524,525 ?EE?SHHHHHHHHHTT??EEEEE??SHHHHHHHHHHHHGGG??EEEE??HHHH-HHH-----------------H--HHHHHHHHHHHTT?-S-------S?-EEEE??SB?S------HHHHHHHHHT--------T?-SEE-------EE??T-------TS?-HHHHHHHHHHHHHHHHHTT--?E---EEEEES??--?-----??--?SS?SS---III-----------IISS??HHHHHHHHHHS??SS-----?EE?SS??SS--SB??-------SSS??--------??HH--H-----------------------------------HHHHHHH?------------------------?S-------?-EEE?S?----------????HHHHHHHHHTT????S?B???HHHHHHHHHTTEEEEEE?HHHHHHHHHHH--------------------HHHHHH?TT?------------??HHHHHHHHHHHHHHHHHHHHH--HH-T?TT?? 3EKL|A PF01117.15_Aerolysin_seed 14 408 !Q:0,1|12,12|17,17|25,25|33,34|36,36|39,39|44,45|52,56|59,59|66,68|70,75|79,79|82,84|103,103|105,106|108,109|123,127|129,129|144,148|151,152|160,160|162,162|165,165|168,172|174,177|179,183|186,186|190,190|194,196|209,211|213,213|244,245|252,252|255,257|260,260|262,263|265,273|275,276|284,285|289,291|295,295|305,305|309,309|313,313|321,321|323,323|333,336|340,342|365,366|369,393|396,396|398,401 Q:2,11|13,16|18,24|26,32|35,35|37,38|40,43|46,51|57,58|60,65|69,69|76,78|80,81|85,102|104,104|107,107|110,122|128,128|130,143|149,150|153,159|161,161|163,164|166,167|173,173|178,178|184,185|187,189|191,193|197,208|212,212|214,243|246,251|253,254|258,259|261,261|264,264|274,274|277,283|286,288|292,294|296,304|306,308|310,312|314,320|322,322|324,332|337,339|343,364|367,368|394,395|397,397|402,407 ??HHHHHHHHHT?TTTT-HHHHHHH-HHHTTBS??S?TT?SSTT-?SEEEEE?----SS-SEEEEE???S?---??STT-TT???EEEEEEEEEEEEEEEEEE?S??B??EEEEEEEEEEEEE?????B?SEEEEEEEEEEEEE-----EE??SSSGGGT?B?SS?EE??-??T----T?????EE?TTS?GGG?-?EEEEEEEEEEEE???B?TTEEEEEEEEEEEEEEEEEEEEEEEEEEEE--EEEEEB?SS???BT-T??T---------T??EEEEEEE--ESS???GGG?HHHHHHTTT?GGG?SSB?HHHHHHH-H?HHHHHHHHH----HHS-??EEEEEEEEEEEEEEEEEEEEEB??EE????-----????????????????EE-E????HHHHHH 1Z52|A PF01118.19_Semialdhyde_dh_seed 188 183 !Q:15,15|22,24|27,27|39,39|50,50|52,59|65,67|72,76|84,86|89,89|95,97|99,99|111,112|117,121|126,128|136,136|146,150|152,153|155,155|162,162|165,166|170,176|182,182 Q:0,14|16,21|25,26|28,38|40,49|51,51|60,64|68,71|77,83|87,88|90,94|98,98|100,110|113,116|122,125|129,135|137,145|151,151|154,154|156,161|163,164|167,169|177,181 EEEEETTTSHHHHHH-HHHHHH--?TT-EEEEEEEEETT?TTTTSBHHHH?G--------GGTTT???BEEE-----ESSGGGT--?TT?SEEEE?--S?HHHHHHHHHHH--HHTT?----EEEE--?SSTTSSS?HHHHHHHTS-----S??S?HHHHHH?EE??TTT--?---?HHHHT? 1GL3|A PF01119.14_DNA_mis_repair_seed 151 148 !Q:4,5|7,7|15,15|20,20|26,33|42,42|44,44|46,50|52,53|59,59|70,71|73,77|89,93|99,103|110,111|117,126|147,147 Q:0,3|6,6|8,14|16,19|21,25|34,41|43,43|45,45|51,51|54,58|60,69|72,72|78,88|94,98|104,109|112,116|127,146 HHHH--H?HHHHHHE-EEEE-EEETT--------EEEEEEEE?G-G-----G??TTGGG?EEEEETTEEE??H-----HHHHHHHHHHH-----HHSSS?????EEEEEE??GGGEE??????????EETTHHHHHHHHHHHHHHHT? 3H4L|A PF01120.12_Alpha_L_fucos_seed 48 568 !Q:0,43|47,49|52,54|65,65|71,72|85,90|93,100|102,102|106,128|133,134|137,138|144,151|155,164|167,169|171,176|178,179|192,192|201,201|204,205|209,215|218,218|220,221|226,231|235,235|237,237|250,250|252,252|257,258|262,263|266,267|270,270|273,275|277,279|285,298|305,349|352,352|365,365|368,369|376,377|381,407|416,418|431,433|435,435|442,442|444,444|447,448|452,452|456,456|458,458|465,465|468,471|475,480|487,487|493,493|498,499|501,503|505,505|510,513|529,529|536,538|542,544 Q:44,46|50,51|55,64|66,70|73,84|91,92|101,101|103,105|129,132|135,136|139,143|152,154|165,166|170,170|177,177|180,191|193,200|202,203|206,208|216,217|219,219|222,225|232,234|236,236|238,249|251,251|253,256|259,261|264,265|268,269|271,272|276,276|280,284|299,304|350,351|353,364|366,367|370,375|378,380|408,415|419,430|434,434|436,441|443,443|445,446|449,451|453,455|457,457|459,464|466,467|472,474|481,486|488,492|494,497|500,500|504,504|506,509|514,528|530,535|539,541|545,567 ------------------------------????------????SSS???SS???SHHHHHHHHH?EEEEE??SGGGTTTTEETT------EE?-?-----S?GGG-----------------------HHHH--TT??HHHHH--------GGG----------GG???T------T??HHHHHHHHHHHT?SEEEEEEE?TT??BSS??-----TT?S-?BGGG------STT?S?HHHHHHHHHHHT-T?EEEE--EEE--SS-?TT?TT?-?S???SHHHH--------------HHHHHH---------------------------------------------HH-HHHHHHHHHHHH?TT??EEEEES??SHH---------------------------HHTTHHHH---HHHHHHHHHHST---T?EEBGGG?B?TT??BSB?TTS?B?SSBEEE?SS????TTT-----?GGGGGS?EEEEE?SSSS??S??-S?GGGS????HHHHHHHHHHHHHTT?EEEEEE???TTS???HHHHHHHHHHHHHHHHHGGGTTT 3EYP|A PF01121.15_CoaE_seed 13 190 !Q:6,7|11,11|22,22|25,26|42,42|53,56|61,61|64,65|69,69|106,107|109,111|118,118|125,125|131,131|139,140|153,153|155,156|168,169|177,177|183,184|187,187 Q:0,5|8,10|12,21|23,24|27,41|43,52|57,60|62,63|66,68|70,105|108,108|112,117|119,124|126,130|132,138|141,152|154,154|157,167|170,176|178,182|185,186|188,189 EEEEEE??TTS?HHHHHHHHHH-TT??EEEHHHHHHHTTSTT?HHHHHHHHHH?---GGGB?TT--SSB?HHHHHHHHHHSTTHHHHHHHHHHHHHHHHHHHHHHH??S---SEEEEE?TTTTTT-TGGGG?SEEEEEE??HHHHHHHHHHHH-T??HHHHHHHHHHS??HHHHHHH?SEEEE?-SS?GG 1VIY|A PF01122.14_Cobalamin_bind_seed 11 350 !Q:0,19|21,26|43,45|49,50|64,65|85,86|89,90|92,92|94,94|97,100|116,125|148,148|153,155|158,158|174,177|191,196|219,226|249,249|253,253|270,273|296,299|313,314|321,323|326,328|331,349 Q:20,20|27,42|46,48|51,63|66,84|87,88|91,91|93,93|95,96|101,115|126,147|149,152|156,157|159,173|178,190|197,218|227,248|250,252|254,269|274,295|300,312|315,320|324,325|329,330 ------------------??S??????HHHHHHHHHHHGGGGG???TTT??HHHHHHHHTSSEE??HHHHHHHHHHHHHHHHHHS??SS??S?S?SS????HHHHHHHHHHHHHTT????------SHHHHHHHHHHHHHHHHHHHHH?TTSS???SS?HHHHHHHHHHHHHTT????HHHHHHHHHHHSS---???STTHHHHHHHHHHHHHHHHTTT??------GGGHHHHHHHHHHHHHHHHHTB?TTS?BSSTTTHHHHHHHHTT????SSHHHHHHHHHHHHHHHHHTTT????HHHHHHHTTGGGT??GGGGSS-??SS???EE--??-----?????????? 2V3P|A PF01123.15_Stap_Strp_toxin_seed 22 106 !Q:8,9|15,17|19,21|23,23|32,38|42,44|51,51|61,61|65,65|71,72|74,74|77,94|100,101|105,105 Q:0,7|10,14|18,18|22,22|24,31|39,41|45,50|52,60|62,64|66,70|73,73|75,76|95,99|102,104 HHHGGGSS??EEEEE---E???B?SSTTEEEE????---TTT???SEEEEE?SSHHHHHHH-TTS?EEEEE??B?TT??????????????????EEEEE??EEE? 3EA6|A PF01124.13_MAPEG_seed 319 241 !Q:2,3|7,10|32,57|62,63|65,76|89,125|150,150|152,173|193,193|197,199|203,209|212,213|217,217|220,223 Q:0,1|4,6|11,31|58,61|64,64|77,88|126,149|151,151|174,192|194,196|200,202|210,211|214,216|218,219|224,240 HH--HHH----HHHHHHTHHHHHHHHHHHHHH??-----------------------?STTS??S--------????SSHHHHHHHHHH-------------------------------------HHHHHHHHHHHHHHHHHHHHHHHS-S----??-----------?----HHHHHHHHHHHHHHHHHHH-HHT---TSS-----??GG--GGH-HH----HHHHHSSHHHHHHHHHH 3DWW|A PF01126.15_Heme_oxygenase_seed 18 262 !Q:0,1|30,32|67,68|70,70|73,74|87,89|96,99|116,119|144,191|199,199|203,204|206,206|210,211|214,214|216,218|234,237 Q:2,29|33,66|69,69|71,72|75,86|90,95|100,115|120,143|192,198|200,202|205,205|207,209|212,213|215,215|219,233|238,261 ??HHHHHHHHTHHHHHHHHTSHHHHHHHTT???HHHHHHHHHHHHHHHHHHHHHHHHTTTSTTGGGG??T-TS??HHHHHHHHHHHH-?-TTHHHH????HHHHHHHHHHHHHHHH---?GGGHHHHHHHHHHHHHHHHHHHHH------------------------------------------------HHHHHHT?SSS--S?GGG??TT?S---SHHHHHHHHHHHHHT????HHHHHHHHHHHHHHHHHHHHHHHH 3K4F|A PF01127.17_Sdh_cyt_seed 125 190 !Q:0,16|18,20|22,27|31,39|58,59|66,73|75,75|83,84|87,87|93,101|108,114|122,122|143,144|146,148|150,150|154,155|158,158|162,169|174,174|179,179 Q:17,17|21,21|28,30|40,57|60,65|74,74|76,82|85,86|88,92|102,107|115,121|123,142|145,145|149,149|151,153|156,157|159,161|170,173|175,178|180,189 ??????-----------B???G------GGS?---?-?--HHHHHHHHHHHHHHHHHH--HHHHHH--------H-HHHHHHH-?HH-HHHHH---------HHHTTS-------HHHHHHH-HHHHHHHHHHHHHHHHHHHH--H---H-TSS??SH-HHH--------HHHH-HHHH-HHHHHHHHHH 3AE5|C PF01128.14_IspD_seed 6 232 !Q:7,10|14,15|18,18|51,51|54,56|65,66|68,68|76,77|91,91|95,97|103,104|107,107|110,111|125,125|128,128|135,136|138,138|143,144|155,156|159,159|181,182|187,190|200,200|202,204|209,210|213,217|230,231 Q:0,6|11,13|16,17|19,50|52,53|57,64|67,67|69,75|78,90|92,94|98,102|105,106|108,109|112,124|126,127|129,134|137,137|139,142|145,154|157,158|160,180|183,186|191,199|201,201|205,208|211,212|218,229 EEEEEEE????GGG??SS?GGGSEETTEEHHHHHHHHHHTSTTEEEEEEEE?TT?-?SGGGSGGG--G?TTEEEEE??SSHHHHHHHHHHT-STT?--SEEEE??TT?TT??HHHHHHHHGGGGT?SS?EEEEEE??S?EEEE?-TTSSSEEEEE??TT?EEEEEEEEEEHHHHHHHHHHH--HHTT????SHHHHHHHT-T???EEEE??TT?????SHHHHHHHHHHH?? 1HV9|A PF01129.13_ART_seed 9 271 !Q:2,3|7,11|14,14|22,22|34,34|50,59|62,67|72,85|88,89|103,108|120,123|127,127|131,133|148,153|155,156|159,163|168,168|170,175|177,177|181,181|185,186|189,190|192,192|198,198|208,209|213,213|222,222|225,225|231,231|235,235|240,240|250,253|268,270 Q:0,1|4,6|12,13|15,21|23,33|35,49|60,61|68,71|86,87|90,102|109,119|124,126|128,130|134,147|154,154|157,158|164,167|169,169|176,176|178,180|182,184|187,188|191,191|193,197|199,207|210,212|214,221|223,224|226,230|232,234|236,239|241,249|254,267 ES??TTS?????TT?HHHHHHH-HHHHHHHHHHH?HHHHHHHHHHHHHHH----------HH------GGGS?-----------??TT??HHHHHHHHHHTST------THHHHHHHHHT----GGG?GGG???HHHHHHHHHHHHHH??----S??EE-----EEEE?S------S?EEE?SSS-?EE??S?EEEES?HHHHHSTTT??TTS?EEEEEESS?EE?TTTSS?GGG?EEEE?TTEEEEEEE----EETTTEEEEEEEEE??? 1GXZ|A PF01130.16_CD36_seed 52 713 !Q:0,27|31,31|33,34|36,38|40,40|42,48|56,65|67,67|71,71|73,81|89,89|96,97|99,101|113,113|128,129|135,136|145,145|148,150|155,159|163,163|169,169|179,180|182,193|198,244|255,258|260,261|264,264|275,285|288,288|291,292|299,307|309,309|313,323|327,327|332,334|337,340|342,343|348,348|352,353|360,369|379,381|384,398|404,410|412,412|414,418|420,421|424,425|428,430|432,433|435,437|439,439|441,442|446,449|453,453|456,456|459,461|470,470|481,483|490,490|492,494|500,516|521,551|557,557|562,564|567,574|579,579|584,585|588,588|597,597|599,603|608,610|615,615|619,620|624,624|636,638|641,644|650,653|667,667|669,670|678,678|682,712 Q:28,30|32,32|35,35|39,39|41,41|49,55|66,66|68,70|72,72|82,88|90,95|98,98|102,112|114,127|130,134|137,144|146,147|151,154|160,162|164,168|170,178|181,181|194,197|245,254|259,259|262,263|265,274|286,287|289,290|293,298|308,308|310,312|324,326|328,331|335,336|341,341|344,347|349,351|354,359|370,378|382,383|399,403|411,411|413,413|419,419|422,423|426,427|431,431|434,434|438,438|440,440|443,445|450,452|454,455|457,458|462,469|471,480|484,489|491,491|495,499|517,520|552,556|558,561|565,566|575,578|580,583|586,587|589,596|598,598|604,607|611,614|616,618|621,623|625,635|639,640|645,649|654,666|668,668|671,677|679,681 ------------------??????????GGG?S??T---T?H-------HHHHHHS?--------?S?EEE-E---------EEEEEES?HHHHHT--T???BEEEEEEEEEE-EEEEEEEEEEEGGG--TEEEE--EEEEEEEE?GG---GSSS----?TTT?EEEEE?HHHHHHHHH??S------------HHHH-----------------------------------------------HHHHHHHHHT----T??SE-EEEEHHHHHH----------?EE?HH--HHHHHH---------H?TTS----------?SEE?TTTT--?SS?--?S??EEEE?TTS-?GGGTTE----------EEEETTBSB?--SS---------------SSSTT-------T-T-----B??SB-?SS???S--S-??T-T??EEE--??GGG-TS?EE---EEEEEEEE-ETTEEEEEEE??-GGGGSS?G---GGGGG----------------?TTTT?---------------------------???TTEEE?TTTT---TT--??----EEEE?GGGT--TS?HHHHHTSB-T??-??HHHH?-?EEEE?TTT??EEE-EEEEEEEEEEE???TT--?-GGGTT-??-SEEEEEEEEEEEE-E??HHHHHHH-HTT??----------------------------- 4F7B|A PF01131.15_Topoisom_bac_seed 126 701 !Q:0,2|26,26|33,49|52,56|76,83|85,86|88,89|94,96|99,111|113,132|134,134|138,138|142,161|172,175|179,180|192,203|206,211|214,215|223,224|227,232|234,234|247,250|264,272|275,278|282,284|287,294|297,302|304,304|317,317|319,322|326,330|333,361|363,363|366,367|370,372|376,376|379,390|395,400|402,403|416,421|424,425|436,438|441,447|450,452|455,458|469,471|477,479|481,518|520,522|524,524|528,533|540,541|544,551|554,562|574,598|600,602|615,617|625,629|634,636|640,640|648,648|652,657|661,666|669,670|673,673|693,694 Q:3,25|27,32|50,51|57,75|84,84|87,87|90,93|97,98|112,112|133,133|135,137|139,141|162,171|176,178|181,191|204,205|212,213|216,222|225,226|233,233|235,246|251,263|273,274|279,281|285,286|295,296|303,303|305,316|318,318|323,325|331,332|362,362|364,365|368,369|373,375|377,378|391,394|401,401|404,415|422,423|426,435|439,440|448,449|453,454|459,468|472,476|480,480|519,519|523,523|525,527|534,539|542,543|552,553|563,573|599,599|603,614|618,624|630,633|637,639|641,647|649,651|658,660|667,668|671,672|674,692|695,700 ???HHHHHHHHHHHHHHHHHHHHHHH-HHHHHT----------------?TT?-???TTHHHHHHHHHHHHHHHHT??----??E--E--EEEE---EE-------------E--------------------E?TTS?EEE--------------------EEEEEETTEE????SHH--HHHHHHHHHHH----??------EE------EE--EEEEEEE--EE-?????B?HHHHHHHHHHHH?-??HHHHHHHHHHHHH---------TT----SBS--?SS???????-HH------H-HHHHHHHHHHHT?G----GGS?----SS?????---???-------???---?????B?BS-?TT-??GGG?SS??----------HHHH------H--HHHHHHHHHHHH------TS??EEEEEEEEEE---EE-------TT---EE----EEEEEEEEEE--?GGGGT---S-------?????????-------------?????--??T---T?EEE------EEEEEE--EE--------EE????-????HHHHHHHHHHT-------------------------T???TTTHHHHHHHHH---HTTSEEE-----ETTE---EEE?HHHHHHH-HHH------HHH---?--HH--HH?HHHHHHHHHHHHHHHTTSS?-HHHHHH 1CYY|A PF01132.15_EFP_seed 271 67 !Q:12,12|14,14|19,19|22,22|24,25|31,33|39,39|45,46|48,49|51,51|58,59|62,62 Q:0,11|13,13|15,18|20,21|23,23|26,30|34,38|40,44|47,47|50,50|52,57|60,61|63,66 EEEEEEEEEETT-E-EEEE?TT-T??EEEEE---HHHHT-TTTTT??T--T?EEEEEE--ET-TEEE 3OYY|A PF01133.12_ER_seed 13 104 !Q:0,2|9,9|11,11|13,13|17,17|44,44|47,47|50,53|83,83|102,103 Q:3,8|10,10|12,12|14,16|18,43|45,46|48,49|54,82|84,101 ???EEEEEE?S-S?GGG?EEEEESSHHHHHHHHHHHHHHHHHHH?TT?SS????HHHHHHHHHHSSEEEEEEEETTTTEEEEE?HHHHHHHHHHHHHHHHHH?? 1W9G|A PF01134.17_GIDA_seed 122 523 !Q:5,6|22,23|28,42|44,44|50,52|59,59|61,65|79,80|93,94|97,98|101,101|105,105|112,112|127,129|137,139|148,163|169,169|176,176|182,189|194,195|198,207|210,210|224,224|228,230|232,232|240,240|242,242|245,247|255,256|263,265|268,268|272,275|278,278|280,284|286,286|294,294|297,298|300,321|327,328|332,337|347,347|349,349|351,351|353,358|360,361|363,363|367,367|373,375|380,380|382,396|398,401|409,409|412,413|415,415|421,426|437,437|441,441|444,445|449,455|463,464|469,470|472,472|474,474|485,485|492,493|495,496|503,504|516,516|522,522 Q:0,4|7,21|24,27|43,43|45,49|53,58|60,60|66,78|81,92|95,96|99,100|102,104|106,111|113,126|130,136|140,147|164,168|170,175|177,181|190,193|196,197|208,209|211,223|225,227|231,231|233,239|241,241|243,244|248,254|257,262|266,267|269,271|276,277|279,279|285,285|287,293|295,296|299,299|322,326|329,331|338,346|348,348|350,350|352,352|359,359|362,362|364,366|368,372|376,379|381,381|397,397|402,408|410,411|414,414|416,420|427,436|438,440|442,443|446,448|456,462|465,468|471,471|473,473|475,484|486,491|494,494|497,502|505,515|517,521 EEEEE??SHHHHHHHHHHHHTT??EEEE--------------?S?GGGTT???SSSEEE?T-----THHHHHHHHHHHT-?SHHHHHHHHEEE??EE??SS?STT?EEEEEE?HHHHHHHHHHHHHT---STTEEEE???EEEEEEET----------------TEEEE-EEETTS?EEEEE--------EEEE??TT---------?BT?EEEETTEEEESSS-TTS-??B?THHHHHH-H-TT???EEEEEEE??EEEGGG???SS?EEE???-SS?B?----S?SSSSSTT?SB??S?---???------------??-EEEEE??HHH------HHHHHHTGG-G?T-T????--B??S?TTT?SSTTT---TTTT?T---------------T????EEEEEES?SS??E-EEEES??????HHHHHHHHTT-STT?TT??EEE?-----?EEEEEEE??GGGB?-T-T?BBSSSBTEEE?GGGGTB-?S--HHHHHH--HHHHHHHHHHH-HHHTS? 3CES|A PF01135.14_PCMT_seed 9 232 !Q:0,2|16,17|29,29|34,34|37,42|48,48|51,51|55,60|63,64|80,80|83,83|90,90|93,93|107,112|120,120|135,135|140,140|151,151|160,161|174,175|194,195|199,199|208,208|212,212|222,224|226,228 Q:3,15|18,28|30,33|35,36|43,47|49,50|52,54|61,62|65,79|81,82|84,89|91,92|94,106|113,119|121,134|136,139|141,150|152,159|162,173|176,193|196,198|200,207|209,211|213,221|225,225|229,231 ??-HHHHHHHHHHTTS??SHHHHHHHHHS?GGGT?SS-----?TTSSS?EE?STT-----?EE??HHHHHHHHHHTTGGG?TT?EEEEET?TT?HHHHHHHHHSTTT?-----EEEEEES?HHHHHHHHHHHHHH?THHH-HTSSEEEEES?GGGTTGGG??EEEEEESSBBSS??HHHHHTEEEEEEEEEEES?-TTS?EEEEEEEE?TTS?EEEEEEEEE???B???HHH 3BKX|A PF01137.16_RTC_seed 29 382 !Q:1,1|23,25|29,29|39,40|42,43|58,59|63,64|68,68|70,70|75,91|93,93|97,106|109,109|128,128|139,139|143,144|161,161|165,167|173,174|179,180|189,199|201,204|206,207|209,210|225,225|241,242|251,251|254,276|278,278|292,292|300,301|304,305|324,324|328,328|344,347|354,355|357,358|371,371|374,377|381,381 Q:0,0|2,22|26,28|30,38|41,41|44,57|60,62|65,67|69,69|71,74|92,92|94,96|107,108|110,127|129,138|140,142|145,160|162,164|168,172|175,178|181,188|200,200|205,205|208,208|211,224|226,240|243,250|252,253|277,277|279,291|293,299|302,303|306,323|325,327|329,343|348,353|356,356|359,370|372,373|378,380 E?TTSTTTSSHHHHHHHHHHHHH???EEE-SSTTTTBSS-?S??HHHHHHHHHHHHHS??EEE??STT?S?EEEE?-----------?????S-EEE???------?SS?BHHHHHHHHHHHGGGSSS?EEEEEEEBSB?SSS??HHHHHHHHHHHHHHHT?EEE---EEEEE??BTTS??EEEEEEEE--------???S????B??B??SEEEEEEEEEEESS?HHHHHHHHHHHHHHS??SEEEEEEE?GG-----------------------G?SEEEEEEEEEESS?EEEEEEE??TT??HHHHHHHHHHHHHHHHTS?BSB?HHHHHHHHHHHHHTT?--?EEEESS??H--HHHHHHHHHHHH-SS???-EEE? 3PQV|A PF01138.16_RNase_PH_seed 192 362 !Q:9,10|12,13|16,16|21,35|44,61|63,64|74,74|76,78|80,110|113,114|116,128|136,139|145,166|170,170|172,174|176,181|186,194|199,202|204,210|212,223|232,241|243,253|255,263|265,265|275,292|294,315|317,336|338,338|345,348|360,360 Q:0,8|11,11|14,15|17,20|36,43|62,62|65,73|75,75|79,79|111,112|115,115|129,135|140,144|167,169|171,171|175,175|182,185|195,198|203,203|211,211|224,231|242,242|254,254|264,264|266,274|293,293|316,316|337,337|339,344|349,359|361,361 TTEEEEEEE--S--SS?TTSS---------------EEEEEEET------------------T--EEEEEEEEE?S---S?-----------------------------?TT??S??-----------EEEEEEE?---GGGGT????------------------STT?S?-?S----??HHHH---------HHHH----H-------H------------HHHHGGGB?---------T-----------T??-------S?EEEEEEEEE?----------------?S----------------------S--------------------S?HHHHHH----HHHHHHHHHHT?S 1R6L|A PF01139.12_RtcB_seed 136 785 !Q:0,0|3,3|8,11|19,32|46,46|49,53|57,59|61,62|71,72|75,75|77,77|87,88|91,91|94,94|99,99|104,104|110,112|114,114|120,124|126,126|128,130|133,135|147,148|150,160|163,171|173,173|175,177|181,181|194,194|199,199|201,201|204,210|220,221|223,233|235,236|241,241|250,260|262,269|273,275|279,279|285,292|295,296|298,300|304,304|312,312|314,315|317,324|327,330|338,339|343,345|357,360|363,366|370,438|441,441|444,445|481,504|507,509|514,514|516,518|524,526|529,540|549,559|563,576|581,595|609,609|612,615|617,617|619,619|623,624|631,632|637,639|643,643|649,650|656,660|662,662|668,669|671,672|676,676|683,701|703,704|716,718|720,720|726,726|730,745|750,750|755,756|784,784 Q:1,2|4,7|12,18|33,45|47,48|54,56|60,60|63,70|73,74|76,76|78,86|89,90|92,93|95,98|100,103|105,109|113,113|115,119|125,125|127,127|131,132|136,146|149,149|161,162|172,172|174,174|178,180|182,193|195,198|200,200|202,203|211,219|222,222|234,234|237,240|242,249|261,261|270,272|276,278|280,284|293,294|297,297|301,303|305,311|313,313|316,316|325,326|331,337|340,342|346,356|361,362|367,369|439,440|442,443|446,480|505,506|510,513|515,515|519,523|527,528|541,548|560,562|577,580|596,608|610,611|616,616|618,618|620,622|625,630|633,636|640,642|644,648|651,655|661,661|663,667|670,670|673,675|677,682|702,702|705,715|719,719|721,725|727,729|746,749|751,754|757,783 ?SS?EEEE?--?HHHHHHH--------------HTSSHHHHHHHHT-TS-----TTB--?S-?EEEEEEEE??SS-S?EEEEEEEET--TT?EE?GGGT?SSTT?EEEEE??-S?BHHHH-----G-G---GH---HHHHHHHHHHS??S-----------TT------???S-S???TTS?HHHHHHTHHHHH-HTTS-S?GG-------GGGGSGGGG??T-----------T??GGGS?HHHHHHHG-----------G--------GSS???STT?EEEEE--------EE--E---EES?HHHHHHH-T??T--------TB----EEEEEEE??TTT???HHHHHHHHHHH----HG----GGS?---?--???-----------------------------------------------------------SG-GG??EETTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH------------------------HH---HHHH?S?--TTTTT???EE------------EEEESEEE-----------EEE--------------EEEE---------------TTEEEEEEEEEES?EE???-T-T?TTS?-GGGTTT??EEEE???TTS?EEEEE??HHHHH-----H-SSSEE??S??BSS?HHHHHH-------------------H??HHHHHHHHHHT---T?EEEES?HHH----------------HHHT?GGGB??HHHHHHHHHHHTSSEEEEEEEEEEEEE? 4ISJ|A PF01140.14_Gag_MA_seed 9 139 !Q:0,9|30,33|49,49|52,53|56,59|73,73|78,78|95,96|99,138 Q:10,29|34,48|50,51|54,55|60,72|74,77|79,94|97,98 ?????----?HHHHHHHTHHHHHHHHHHTT????HHHHHHHHHTTGGGG?SS??TT????HHHHHHHHHHHTS?TTSS?GGGHHHHHHHHHHHHS??TT?-----??-------------------------------- 1UHU|A PF01142.13_TruD_seed 69 512 !Q:0,14|22,23|25,27|30,30|32,36|39,39|42,47|58,64|67,68|72,72|82,83|97,98|107,109|122,123|125,126|130,134|138,153|163,163|168,170|173,173|184,186|188,188|192,192|194,195|218,221|226,226|230,231|243,243|250,252|257,259|263,263|277,278|287,287|290,290|294,300|313,313|322,322|348,352|355,356|360,361|364,365|368,368|370,370|374,376|378,378|382,386|391,392|404,404|408,409|411,411|414,414|416,421|426,426|438,439|445,446|449,449|453,459|461,462|468,471|473,477|479,480|483,483|489,489|496,496|502,503 Q:15,21|24,24|28,29|31,31|37,38|40,41|48,57|65,66|69,71|73,81|84,96|99,106|110,121|124,124|127,129|135,137|154,162|164,167|171,172|174,183|187,187|189,191|193,193|196,217|222,225|227,229|232,242|244,249|253,256|260,262|264,276|279,286|288,289|291,293|301,312|314,321|323,347|353,354|357,359|362,363|366,367|369,369|371,373|377,377|379,381|387,390|393,403|405,407|410,410|412,413|415,415|422,425|427,437|440,444|447,448|450,452|460,460|463,467|472,472|478,478|481,482|484,488|490,495|497,501|504,511 ?-???----------HHHHTTT??S?--SS?S?????BS?SS------GGGEEEEEEE--?-???BS-?SSE-EEEEEEEES??HHHHHHHHHHHHT??GGGEEESS???SSSEEEEEEEEE--T??HHH-----HTS?---------??----TTEEEEEEE-EESS???TT?EEEEEEEEEE---E-EES-S-?HHHHHHHHHHHHHHHHHHTEEE????TTTT?SSS??HHHHHHHHHHT?HHHHHH---HHHS???TTS?TTHHHHHHHHHHH??HHHHHHHS?TT?HHH-------HHHHHHHHHSTT?GGGGGTTS?HHHHHHHHHHHHHHHHHHHHHHHHH-----TT??SSS??TT??EE?B?SSS--?B?SSS?????TTTH--HHHHHHHTTTS?EEB??B?SS-S????-?SHHH-HHHHHHHHHTT??GGGSS?-SS?GGG??---??B??BSEEE?-??B?---?E--EE?TTSTT?EEEEEB?EEETT??THHHHHHH 1SB7|A PF01144.18_CoA_trans_seed 43 283 !Q:2,2|9,9|11,12|15,15|20,21|27,29|41,47|53,53|56,59|62,63|75,75|81,84|87,90|92,99|112,112|117,118|133,136|146,146|152,154|159,159|162,164|171,175|181,190|199,201|209,209|216,217|220,221|225,225|234,244|258,260|265,265|269,269|272,272|276,277|282,282 Q:0,1|3,8|10,10|13,14|16,19|22,26|30,40|48,52|54,55|60,61|64,74|76,80|85,86|91,91|100,111|113,116|119,132|137,145|147,151|155,158|160,161|165,170|176,180|191,198|202,208|210,215|218,219|222,224|226,233|245,257|261,264|266,268|270,271|273,275|278,281 ES?HHHHHT-T??TT?EEEE??BTTBT-??HHHHHHHHHHT-----??SEEEE?SS?--?BT--TBTTHHHHHTT?EEEEE----ES?-??S-------?HHHHHHHHHTSS-EEEE??HHHHHHHHHHHHHT??--EEEESTTTT-SHHHH???EEEE?TT---SSEEEE?????EEEET----------TEEEEEEE???EEEEEEE?SEEETT??EE??GGG?TTHHHHTT-----------SEEEEEEEESEEE--?TTSS?GGG?SB?GGG??EEEE? 3K6M|A PF01145.20_Band_7_seed 120 554 !Q:0,124|128,135|138,139|147,192|194,194|198,198|202,213|218,220|225,225|228,229|232,257|259,259|268,283|285,292|310,313|317,317|319,321|326,334|336,357|359,359|372,429|432,452|458,479|482,482|485,486|490,490|499,501|507,509|521,542 Q:125,127|136,137|140,146|193,193|195,197|199,201|214,217|221,224|226,227|230,231|258,258|260,267|284,284|293,309|314,316|318,318|322,325|335,335|358,358|360,371|430,431|453,457|480,481|483,484|487,489|491,498|502,506|510,520|543,553 ----?-----------------------------------------------------------------------------------------------------------------------?EEE??---???SS-?EEEEEEE----------------------------------------------E-EEE?TTS-----------?EEEE---EEEE-EE--EE--------------------------S?HHHHHHSS----------------S?-------HHHHHHHHHHHHHHHHH----HTS?H---HHHH---------H?---------------------H-HHHHHHHHHHHH----------------------------------------------------------HH---------------------TGGGT----------------------EE-EE--EEE-EEEEEEET---THHHH---HHHHHHHHHHH----------------------HHHHHHHHHHH 4FVF|A PF01147.12_Crust_neurohorm_seed 45 76 !Q:0,0|2,2|5,6|12,12|32,32|45,45|58,59|61,61|74,74 Q:1,1|3,4|7,11|13,31|33,44|46,57|60,60|62,73|75,75 ?S-SS??SSTTT?SSHHHHHHHHHHHHHHHHT?HHHHHHHTSSTT?SSHHHHHHHTTS??S-THHHHHHHHHHT-T 1J0T|A PF01149.19_Fapy_DNA_glyco_seed 109 360 !Q:0,1|13,15|18,18|23,23|28,28|33,44|46,46|51,52|55,60|64,66|71,72|85,171|174,189|194,195|197,197|201,201|206,271|273,291|295,298|301,302|305,306|310,317|319,319|322,345|351,351|354,356 Q:2,12|16,17|19,22|24,27|29,32|45,45|47,50|53,54|61,63|67,70|73,84|172,173|190,193|196,196|198,200|202,205|272,272|292,294|299,300|303,304|307,309|318,318|320,321|346,350|352,353|357,359 ??HHHHHHHHHHH---HH-HHBT?EEEE-EEES----------??B-SSSB??HH------HHH-??SEEB?-EEEEETTEEEEE?--------------------------------------------------------------------------------------SS----------?-----EEEE--E?TTT?EEEE------------------------------------------------------------------E-------------------SSS????TT??EE--EEE--------T-TS?-----------------------EEEEE?SS???EEE 3GP1|A PF01150.12_GDA1_CD39_seed 9 560 !Q:3,3|16,16|19,19|34,34|41,41|45,45|51,53|55,56|70,70|77,79|113,114|125,125|133,133|139,140|158,159|163,165|168,169|176,177|195,196|200,200|206,206|210,210|215,218|224,224|227,227|234,237|240,243|247,248|251,253|261,261|265,267|298,306|317,317|320,320|328,328|332,332|334,336|339,339|343,345|362,362|368,372|379,380|387,388|392,392|394,394|399,400|403,404|409,411|426,426|429,435|438,443|452,454|456,456|461,461|463,463|479,479|482,485|488,497|509,509|512,514|525,525|529,530|534,554 Q:0,2|4,15|17,18|20,33|35,40|42,44|46,50|54,54|57,69|71,76|80,112|115,124|126,132|134,138|141,157|160,162|166,167|170,175|178,194|197,199|201,205|207,209|211,214|219,223|225,226|228,233|238,239|244,246|249,250|254,260|262,264|268,297|307,316|318,319|321,327|329,331|333,333|337,338|340,342|346,361|363,367|373,378|381,386|389,391|393,393|395,398|401,402|405,408|412,425|427,428|436,437|444,451|455,455|457,460|462,462|464,478|480,481|486,487|498,508|510,511|515,524|526,528|531,533|555,559 HHS?EEEEEEEEEEEE?SS?EEEEEEEEEEEEET-TTEEEE?GGG?EEEEE???B??HHHHHHHHHHHHT?TTTTTS???GGGGGGGHHHHHHHHHHHHHHHHHHHHHHHHHH??HHHHHHHHHH?EEEEEEE?TTSTT??TTHHHHHHHHHHHHHTS??GGG???EE??TTTSEE??HHHHHHHHHHHHHHHTT??SSS?SEEEE?TTS?EEEE????EEEEE?SS?EEEEEE??--TT????TTS??EE---TTTTTSS?TTS???EEEEEEEGGGSHHHHHHHHHHHHTTSTTTE---------ETTEEEETTS?BT?EEESSSB?EEE?T---TS?EEE???GGGBTTHHHHHHSSTT?HHHHT-----STTHHH--HHHTTT??TTS?H-HHHH??TT??EEEE???HHHHHHHHHHHTTS?SS???????TT??????HHHHHHHS???S?EEEE?H-HHHHHHHHHHHTTSS?TT????HH----------HHHHHHHHHHT?EE---EEETTEEEEE?STT??EEE-------------------??TTTTT 3CJ1|A PF01152.16_Bac_globin_seed 12 126 !Q:0,0|11,11|26,26|37,38|59,60|67,67|69,70|79,83|102,104|123,125 Q:1,10|12,25|27,36|39,58|61,66|68,68|71,78|84,101|105,122 ?HHHHHTHHHH-HHHHHHHHHHHHHH?GGGHHHHHHS?-SSTHHHHHHHHHHHHHHTTS??HHHHHH?S??HHHHHTTS--???HHHHHHHHHHHHHHHHHH???HHHHHHHHHHHHHHHHHH??? 1MWB|A PF01153.14_Glypican_seed 15 663 !Q:0,23|25,25|34,34|38,39|43,44|47,47|49,50|53,53|57,58|64,65|126,126|151,171|187,225|227,228|262,268|287,292|295,296|298,298|316,316|335,335|348,348|351,414|416,423|454,465|468,468|474,477|479,482|491,491|493,493|496,498|501,503|524,556|559,662 Q:24,24|26,33|35,37|40,42|45,46|48,48|51,52|54,56|59,63|66,125|127,150|172,186|226,226|229,261|269,286|293,294|297,297|299,315|317,334|336,347|349,350|415,415|424,453|466,467|469,473|478,478|483,490|492,492|494,495|499,500|504,523|557,558 ???----------???????????B?HHHHHHHH-HTT??SSS??SB?B??TT?SSS-?SSSBS??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHHHHTS?--?----------------?HHHHHHHHHHHHHTT??-????????----??????????????----??????S??THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?---???HHHHHHHHHHHTHHHHTT?-----TT??B?HHHHHHHHHHHSTTGGG-GHHHHHHHHHHHHHHGGG-GSSTTSHHHHHH?TT???????????????????????????????????-----????----????????????????T--------HHHHHHHHHHHHHHHTTHHHHHHHHHHHTT?????????--?EE?SSSEE-???S????SSSGGGTT?S-SS???TT???HHHHHHHHHHHHHHHHHHHH---------------------------------HH???????-???-?????-??????????------????????????????????????--------------????????------------------------ 3ODN|A PF01154.12_HMG_CoA_synt_N_seed 4 174 !Q:3,4|13,14|29,30|39,41|45,47|50,51|69,70|81,81|83,84|86,86|90,90|104,107|109,110|135,136|138,138|149,151|159,159|172,172 Q:0,2|5,12|15,28|31,38|42,44|48,49|52,68|71,80|82,82|85,85|87,89|91,103|108,108|111,134|137,137|139,148|152,158|160,171|173,173 HHH??EEEEEEEE??SEEEEHHHHHHHHT??TTIIIIII???EEE???TT??HHHHHHHHHHHHHHHTT??GGGEEEEEEE?S??S?SSS?HHHHHGGGTTTTT????B??EEESGGGHHHHHHHHHHHHHTSTT??S?EEEEEEEEEE???SSTTGGG?EEEEEEEEEESS?S 2HDB|A PF01155.14_HypA_seed 169 188 !Q:0,1|16,16|23,28|30,30|43,46|62,94|99,99|107,108|116,117|124,124|127,129|131,133|137,151|155,155|159,159|161,161|166,168|170,170|173,173|178,178 Q:2,15|17,22|29,29|31,42|47,61|95,98|100,106|109,115|118,123|125,126|130,130|134,136|152,154|156,158|160,160|162,165|169,169|171,172|174,177|179,187 ??HHHHHHHHHHHHHH-HHHHTT-----?S-EEEEEEEEEETT????HHHHHHHHHHHHTTS---------------------------------TTTT?EEEEEEE??EEEETTT??EEEGGG?TT-??S???GGG???-----------?GGG?GGG?S?SSSS???E-EE-EESS?EEEEEEEEE 3A43|A PF01156.14_IU_nuc_hydro_seed 118 896 !Q:0,0|8,13|15,21|23,33|36,36|45,47|49,50|52,52|54,72|74,76|84,84|86,96|98,99|102,103|119,131|133,137|140,142|144,144|148,154|156,164|166,179|182,182|184,203|208,211|217,217|219,320|322,336|338,342|345,353|356,367|375,375|377,378|380,380|383,389|395,395|397,397|408,409|412,420|428,432|437,439|442,460|462,484|486,486|490,510|515,515|517,517|528,535|538,541|546,547|550,551|555,558|560,564|568,582|590,593|596,615|617,617|619,619|628,628|632,632|635,647|649,657|662,663|672,674|676,685|689,702|704,783|785,785|789,789|791,791|795,795|798,806|809,809|812,824|826,826|829,829|832,851|854,857|863,864|867,867|869,875|885,885|889,892|895,896 Q:1,7|14,14|22,22|34,35|37,44|48,48|51,51|53,53|73,73|77,83|85,85|97,97|100,101|104,118|132,132|138,139|143,143|145,147|155,155|165,165|180,181|183,183|204,207|212,216|218,218|321,321|337,337|343,344|354,355|368,374|376,376|379,379|381,382|390,394|396,396|398,407|410,411|421,427|433,436|440,441|461,461|485,485|487,489|511,514|516,516|518,527|536,537|542,545|548,549|552,554|559,559|565,567|583,589|594,595|616,616|618,618|620,627|629,631|633,634|648,648|658,661|664,671|675,675|686,688|703,703|784,784|786,788|790,790|792,794|796,797|807,808|810,811|825,825|827,828|830,831|852,853|858,862|865,866|868,868|876,884|886,888|893,894 ?EEEEEEE?----?S-------H-----------HH-HHHHHHHH---T-?T-T-------------------E---EEEEEEE?S-----------S--SS-?HHHHHHHHHHHHHHT-------------T?----TT---S?EEE-----??S---------S?-------------SS-S-----------?????----TTTS----TTTSS?S------------------------------------------------------------------------------------------------------S?-???--------??S??--?SS?--------HH------------HHHHHHH-H--H?SS?------EEEEE?S?SHHHHHHHHH?-GG---------GGGGEEE-----EEEE???SS-----------------??S-----------------------S-SSS---?----------------?HHHH-H?HHHHHHHHTS--------SS?---EEEE-?HH--HHT----T-----SEE-------------?-HHHHHHH----HH--------------------T?S-HHHHHHHH-HHH-HT?????-----???S-?------?SSEE??THHHHHHH---H---?------GGG--------------E--------------------------------------------------------------------------------E-EEE-E?EEE?SS--------?SS?TT?------------E-EE?TT------------------??SS????EEEEE--EE?H-------HHHHHHHHH-HHG----GG?- 2FF1|A PF01157.13_Ribosomal_L21e_seed 6 99 !Q:0,3|9,9|15,16|20,20|22,24|30,33|36,36|41,43|46,47|50,52|58,58|63,66|77,78|81,82|84,84|90,90|97,98 Q:4,8|10,14|17,19|21,21|25,29|34,35|37,40|44,45|48,49|53,57|59,62|67,76|79,80|83,83|85,89|91,96 ????SSSTT?HHHHS??TTT?S???HHHHH????TT?EEEE???TT??SS???GGGTT?EEEE????SSSEEEEEEE??SS??S?EEEEE?GGGEEE?? 1S1I|Q PF01158.13_Ribosomal_L36e_seed 39 121 !Q:0,0|2,4|7,7|11,12|15,15|18,38|43,45|48,49|65,67|83,85|98,98|117,117 Q:1,1|5,6|8,10|13,14|16,17|39,42|46,47|50,64|68,82|86,97|99,116|118,120 ?S?--SS?SST--TT?SS????-----------??????GGGG---TT??THHHHHHHHHHHHHH???HHHHHHHHHHTTTHH---HHHHHHHHHHHT?HHHHHHHHHHHHHHHHHH-HHH 3J39|i PF01159.14_Ribosomal_L6e_seed 46 155 !Q:3,6|9,9|19,19|21,23|25,38|42,45|47,50|53,64|66,71|74,75|77,83|88,88|99,105|107,111|127,127|130,132|141,144|148,148|152,154 Q:0,2|7,8|10,18|20,20|24,24|39,41|46,46|51,52|65,65|72,73|76,76|84,87|89,98|106,106|112,126|128,129|133,140|145,147|149,151 TTS????EE?TTTSEEEEE-E???S???----------?TTT--??G----GG?????---????T------TT-?S-????--TTTG-GGGHHHHHHH-------H-----HHHHHHHHHHHHHHS-SS---HHHHHHSB????SSS?STT??? 3J39|E PF01161.15_PBP_seed 128 356 !Q:3,4|9,9|11,19|23,33|35,36|40,44|46,71|73,76|78,78|85,114|119,119|122,139|142,142|145,145|149,154|160,161|164,166|169,169|178,194|197,197|200,200|202,202|205,223|226,254|257,259|261,263|266,268|282,293|295,301|304,305|307,309|312,313|319,335|340,341|351,352|355,355 Q:0,2|5,8|10,10|20,22|34,34|37,39|45,45|72,72|77,77|79,84|115,118|120,121|140,141|143,144|146,148|155,159|162,163|167,168|170,177|195,196|198,199|201,201|203,204|224,225|255,256|260,260|264,265|269,281|294,294|302,303|306,306|310,311|314,318|336,339|342,350|353,354 TSB??GGGB?S---------STT??????--???E--EEE??--?T--------------------------T??--E-EEEEEE------------------------------ETTS-TT------------------TT?EE-EEE------EEEEE--TT??-EE?TTTTTTSS--------------???TT?EE?B?TT-------------------SS-----------------------------BS???B???TT?--EEEEEEEEEEESS------------S??-??-?TT??H---HH--HHHHH-----------------HHHE--EEEEEEEEE--EE? 1WKO|A PF01163.17_RIO1_seed 28 233 !Q:7,10|16,34|44,54|61,61|65,73|96,101|114,115|117,117|123,124|131,137|144,144|164,164|167,167|170,170|175,175|181,181|186,188|191,191|196,196|220,228 Q:0,6|11,15|35,43|55,60|62,64|74,95|102,113|116,116|118,122|125,130|138,143|145,163|165,166|168,169|171,174|176,180|182,185|189,190|192,195|197,219|229,232 EEEEEEE----EETTE-------------------EEEEEEEEE?????????-?GGGTTT?TTS???--????HHHHHHHHHHHHHHHHHHHHTT-?????EEEEETTEEEEE??E-ETTEE??BHHHHG-------GGGGGS?HHHHHHHHHHHHHHHHHTS?EE?SS?STTS-EEESS-SEEE???TT?EETT-STTHHHHHHHHHHHHHHHHHTTT??-----??HHHH 1JKL|A PF01165.15_Ribosomal_S21_seed 140 63 !Q:0,3|7,7|10,10|12,16|35,40|57,62 Q:4,6|8,9|11,11|17,34|41,56 ?-??EEE?SS-S?????THHHHTTSSSSTTTTTSS??---?TTTTTTGGGGSHHHHT???-?? 4A2I|U PF01166.13_TSC22_seed 10 62 !Q:0,1|11,11|15,15|47,47|49,51|54,55|58,61 Q:2,10|12,14|16,46|48,48|52,53|56,57 ??STTTGGGGT?TTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHTSSS?S???SS--SS???? 1DIP|A PF01167.13_Tub_seed 11 347 !Q:0,2|5,6|14,14|17,17|22,24|32,35|39,39|62,62|70,73|80,80|90,90|94,94|98,101|104,117|125,126|134,137|140,141|143,145|152,152|154,154|158,163|165,212|215,215|228,229|238,240|260,260|269,269|271,306|308,308|312,312|329,329|332,333|347,347 Q:3,4|7,13|15,16|18,21|25,31|36,38|40,61|63,69|74,79|81,89|91,93|95,97|102,103|118,124|127,133|138,139|142,142|146,151|153,153|155,157|164,164|213,214|216,227|230,237|241,259|261,268|270,270|307,307|309,311|313,328|330,331|334,346 ???TT??EEEEEEE?SS?SSSS???EEEEEEE?---TTS?EEEEEEEEEEESSSSEEEEEES?HHHHTTT????SEEEEE?TTSSEEEEE?SSB?GGG--??TT--------------GGGSSSB??EEEEEEE????SS??S???EEEEEE?B?TTS?-----B????-------------------------------------------?SS-TTSSHHHHHHTT??SSEEEEEE???EEETTTTEEEEEETTEEEE?BTTEEEEE?T------------------------------------T?TTS?SEEEEEEETTEEEEEE?TT??HHHHHHHHHHHHH- 1C8Z|A PF01168.15_Ala_racemase_N_seed 613 435 !Q:17,31|34,34|39,39|47,47|56,57|61,68|70,74|86,109|113,116|120,131|133,133|139,143|145,145|156,160|162,162|169,169|175,175|177,177|182,184|186,202|204,204|212,212|214,214|217,225|229,237|239,241|243,250|254,261|267,269|273,281|283,283|286,289|297,299|302,302|304,315|317,321|324,329|335,335|337,337|342,345|352,363|365,383|386,388|395,403|406,411|413,416|419,419|421,423|429,433 Q:0,16|32,33|35,38|40,46|48,55|58,60|69,69|75,85|110,112|117,119|132,132|134,138|144,144|146,155|161,161|163,168|170,174|176,176|178,181|185,185|203,203|205,211|213,213|215,216|226,228|238,238|242,242|251,253|262,266|270,272|282,282|284,285|290,296|300,301|303,303|316,316|322,323|330,334|336,336|338,341|346,351|364,364|384,385|389,394|404,405|412,412|417,418|420,420|424,428|434,434 EEHHHHHHHHHHHHHHH----?----------SE-EEEE?HHHHHTT?HHHHHHHH--TTT-----?--S-----EEEESSHHHHH------------------------HHH----HTT?----------?S?EEETT?---?S-SGGGHHHHHH-----T-TEEEEE?SHHHH-H-HHHH???S-----------------S?EEEEEEB?S-SS?--------SSS---------B?--H--------HHH--------HHHHH---HHH---------H-TT---?EEEEEEE???SS-T------------T----?TT?-----THHHH-H-HHHH----HHHHTT?--------?--S------------------?EE???HHHHHH?--------TT------S?--?SE-E???GGGGT?---?S 1BD0|A PF01170.13_UPF0020_seed 16 225 !Q:0,0|4,4|7,9|12,12|25,26|30,30|36,36|39,39|52,53|58,61|69,70|92,93|95,95|102,102|118,118|127,128|132,134|136,136|139,146|151,160|165,165|180,180|183,186|194,194|202,207|218,218 Q:1,3|5,6|10,11|13,24|27,29|31,35|37,38|40,51|54,57|62,68|71,91|94,94|96,101|103,117|119,126|129,131|135,135|137,138|147,150|161,164|166,179|181,182|187,193|195,201|208,217|219,224 ?SSS?SS???SS?HHHHHHHHHHTT??TTS?EEETT?TT?HHHHHHHHHHTT??TTTT????SGGGBTT??HHHHHHHHHHHHHHHHHHHHH??S?EEEEES?HHHHHHHHHHHHHTT?GGGEEEEE??GGG???S?TT?----???EEEE??????????HHHH-HHHHHHHHHHHHHH?TT---?EEEEEES?HHHHHTT???--?SEEEEEESSS?EEEEEE 1VQ1|A PF01171.15_ATP_bind_3_seed 33 228 !Q:5,6|28,37|45,46|48,50|52,52|70,73|78,89|91,94|114,115|118,119|124,127|143,144|146,150|155,159|161,165|170,177|180,180|185,185|189,189|191,192|205,207|209,212|220,220 Q:0,4|7,27|38,44|47,47|51,51|53,69|74,77|90,90|95,113|116,117|120,123|128,142|145,145|151,154|160,160|166,169|178,179|181,184|186,188|190,190|193,204|208,208|213,219|221,227 EEEEE??SBHHHHHHHHHHHHHHTTSTT---------?EEEEEEE??S??-S-SHHHHHHHHHHHHHHTT--??EEEE????------??S----SSTTTTHHHHHHHHHHHHT??TT--EEEE????HHHHHHHHHHHHTTT??T-----TGGG?--??S-----EEEE--------TT-EEEE?GGG-S??HHHHHHHHHHTT???B????GGGTTSH-HHHHHHT 3BL5|A PF01172.13_SBDS_seed 103 132 !Q:9,13|16,16|18,19|34,42|45,56|58,58|63,67|73,75|81,85|87,87|96,102|104,105|107,107|122,124 Q:0,8|14,15|17,17|20,33|43,44|57,57|59,62|68,72|76,80|86,86|88,95|103,103|106,106|108,121|125,131 TSEEEEEEE-?---SS?E--EEEEEESSSGGGGG---------TT?----------?S?SSTT?????EEEET---TTTEE-----E?HHHHHHHT-------S-?S?HHHHHHHHHHSSEE???SSSSSSS 2KDO|A PF01174.14_SNO_seed 4 211 !Q:1,2|6,7|19,19|22,31|33,35|43,43|49,50|52,52|65,65|77,79|97,99|102,106|113,115|117,117|128,129|132,132|134,136|138,138|146,147|153,155|166,169|171,172|179,179|182,182|190,190|196,198 Q:0,0|3,5|8,18|20,21|32,32|36,42|44,48|51,51|53,64|66,76|80,96|100,101|107,112|116,116|118,127|130,131|133,133|137,137|139,145|148,152|156,165|170,170|173,178|180,181|183,189|191,195|199,210 E??SSS??HHHHHHHHHTS?EE----------E???SGGGGGG?SEEEE??S?HHHHHHHHHHTT?HHHHHHHHHTT-??EEEETHHHHHHSEESTT?--SS?????SSEEEE???S?TTSSEEEEEE??TT?S---S?EEEEEES??EEEEE?--TTSEEEEEET----T--EEEEEE-ET-TEEEESS?GGGSS?-?HHHHHHHHHHHH 1R9G|A PF01175.13_Urocanase_seed 57 630 !Q:0,9|11,15|17,18|20,21|39,39|43,43|75,76|94,95|99,99|107,107|109,109|113,113|126,128|130,130|138,140|163,166|168,177|180,180|186,187|203,203|211,211|224,225|228,228|246,249|256,256|268,272|274,281|285,287|289,289|292,292|296,296|298,300|303,304|314,315|317,317|319,321|347,348|350,350|352,352|355,355|364,364|366,368|372,382|386,386|397,397|402,402|404,404|412,413|431,431|435,447|458,461|464,464|468,469|471,471|474,479|500,500|506,506|508,508|515,515|523,523|527,527|531,531|546,546|558,558|562,562|572,572|574,574|601,601|605,605|612,612|615,623|625,629 Q:10,10|16,16|19,19|22,38|40,42|44,74|77,93|96,98|100,106|108,108|110,112|114,125|129,129|131,137|141,162|167,167|178,179|181,185|188,202|204,210|212,223|226,227|229,245|250,255|257,267|273,273|282,284|288,288|290,291|293,295|297,297|301,302|305,313|316,316|318,318|322,346|349,349|351,351|353,354|356,363|365,365|369,371|383,385|387,396|398,401|403,403|405,411|414,430|432,434|448,457|462,463|465,467|470,470|472,473|480,499|501,505|507,507|509,514|516,522|524,526|528,530|532,545|547,557|559,561|563,571|573,573|575,600|602,604|606,611|613,614|624,624 ???----???S-----S??S--SSSHHHHHHHHHHHHHT?TTT?SBGGGTEEETTTEESSSSHHHHHHHHHHHHH??TTEEEEEETTEEEEEEE??TTS?SEEEEES?B?GGG?SHHHHHHHHHTT???B?TTTTTTT???TTHHHHHHHHHHHHHHHHHHHS----S--------??TT?EEEEE??STTTTHHHHHHHHTT?EEEEEES?HHHHHHHHHTTS??EE?SSHHHHHHHHHHHHHTT-???EEEEES?HHHHHHHHHHH-----T??-----?SEE???S?TT?TTT-S???TT??HHHHHHHHH--H?H---HHHHHHHHHHHHHHHHHHHHHHHTT??B?B?SS?HHHHHHHT-T?--TTG-----------GGS?BHHHHTTHHH-HTTT?B?EEEEETT??HHHHHHHHHHHHHHSTT?HHH-------------HHHHHHHHHH????SS?EEE??B?TT------HHHHHHHHHHHHHHHTSSSS?EEEEE?S?STTSEE?TTTTTTT?TTS?TTB?HHHHHHHHHHHHHT?SEEEEEESTTT?TTS?EEEEEEEEE?S?HHHHHHHHHHHHHHHHHHHHHHHHTT?HHH-HHHHHH-TT--------?B????? 2FKN|A PF01176.14_eIF-1a_seed 63 73 !Q:0,1|4,5|12,12|25,25|32,32|40,43|46,46|49,50|53,58|61,63|70,70|72,72 Q:2,3|6,11|13,24|26,31|33,39|44,45|47,48|51,52|59,60|64,69|71,71 ??EE??EEEEEE?SSSEEEEEETTS?EEEEEE?SSGGGTT????TT?EE??EE-----?SS?--TTEEEE?S? 1JT8|A PF01177.17_Asp_Glu_race_seed 177 438 !Q:2,2|4,5|15,17|21,29|33,35|42,59|65,65|68,74|76,80|86,89|93,95|97,114|121,135|143,149|152,152|154,185|189,189|191,191|203,207|210,213|216,219|221,224|230,241|244,251|256,259|261,261|263,263|266,268|273,276|293,293|295,300|303,303|305,307|313,319|327,328|333,336|339,340|357,368|372,376|382,383|391,392|395,399|401,409|412,418|421,421|429,432|435,436 Q:0,1|3,3|6,14|18,20|30,32|36,41|60,64|66,67|75,75|81,85|90,92|96,96|115,120|136,142|150,151|153,153|186,188|190,190|192,202|208,209|214,215|220,220|225,229|242,243|252,255|260,260|262,262|264,265|269,272|277,292|294,294|301,302|304,304|308,312|320,326|329,332|337,338|341,356|369,371|377,381|384,390|393,394|400,400|410,411|419,420|422,428|433,434|437,437 EE?S--SHHHHHHHH---HHH---------HHT???SSGGGS----------------??EEEEE?TT-------S?---?HHHHH----TTS---S???---------------HHHHHH---------------HHHHHHH-------HT?S--------------------------------EEE?S?TGGGGGHHHHH-----HH--?-SS?---B-??-HHHHH------------HH--------HHHH----T-T?SE---EEEE??--HHHHHHTHHHHHHHHT-T-----?EE-E???HHHHH-------HHHHHHH--TTGG----GT?-HHHHHHHHHHHHHHHH------------HTT?----SEEEE?-SHHHHHH??GG-----G?--------SS?------EE?HHHHHHH----HH--H 3OUT|A PF01179.15_Cu_amine_oxid_seed 75 514 !Q:0,1|4,7|9,9|12,13|15,15|18,18|20,24|58,62|80,82|89,89|92,92|98,98|104,107|110,115|119,119|122,123|132,132|136,136|153,153|160,160|166,167|170,170|202,202|212,215|218,227|229,233|235,241|244,246|249,249|254,254|261,261|273,273|277,279|281,286|297,297|300,304|311,312|316,317|325,326|332,334|336,338|343,343|349,349|352,354|358,358|360,361|367,383|385,385|394,394|406,407|410,417|420,420|423,423|426,427|429,429|431,434|436,436|445,446|448,448|451,458|462,462|474,476|480,480|482,483|485,487|503,503|509,510 Q:2,3|8,8|10,11|14,14|16,17|19,19|25,57|63,79|83,88|90,91|93,97|99,103|108,109|116,118|120,121|124,131|133,135|137,152|154,159|161,165|168,169|171,201|203,211|216,217|228,228|234,234|242,243|247,248|250,253|255,260|262,272|274,276|280,280|287,296|298,299|305,310|313,315|318,324|327,331|335,335|339,342|344,348|350,351|355,357|359,359|362,366|384,384|386,393|395,405|408,409|418,419|421,422|424,425|428,428|430,430|435,435|437,444|447,447|449,450|459,461|463,473|477,479|481,481|484,484|488,502|504,508|511,513 ??EE----E?TT??S?EE-E-----TTEEEETTEEEEEEEETTTEEEEEEEEEEETTE-----EEEEEEEEEEEEEEEEB???STTGGG?EE?HHHHT?TTTTB????TT------TSS?SS-?EEEEEEEE?TTS?EEEEEEEEEEEEEEEE-EEEEEE?GGGTT?-SE-EEEEEEEEEEEEEEEETTEEEEEEEEEETTS?EEEEEEEEE????EE--------??T-----T??----?TT---TE-EEEE-TTEEEE?EEEEEEEEEEE?TTS---S-?----BEEEEEEEEE?SS?----TTBTTB--TTS??EEEEEEE??BHHHH--?B???GGGT?EEEEE?TT???TTT?S??EEEEE?------?????---??S?TTSHHHHH?GGGGSSEEEEE??TT-----???TT?SS?TT??S?S----S?HHHHHHTT--S?SB-------?SSB?EEEEEEEEEEE???GGG?S--S???EEEEEEEEEESSSSS?TTTTS??SEE 2CFK|A PF01180.16_DHO_dh_seed 12 386 !Q:2,2|17,17|24,24|35,36|45,45|48,48|50,51|53,53|55,56|69,71|73,73|76,76|94,94|97,122|126,126|133,135|138,140|142,142|156,157|160,160|167,169|174,174|200,242|248,249|256,256|258,260|273,273|277,277|283,285|288,294|300,308|334,334|336,336|343,344 Q:0,1|3,16|18,23|25,34|37,44|46,47|49,49|52,52|54,54|57,68|72,72|74,75|77,93|95,96|123,125|127,132|136,137|141,141|143,155|158,159|161,166|170,173|175,199|243,247|250,255|257,257|261,272|274,276|278,282|286,287|295,299|309,333|335,335|337,342|345,385 GG?EEETTEEESSSEEE?TTTTTT?SSHHHHHTTT-?SEEEEEEE?SS?B??S?S??EEEETTTTEEEE???S?BS?HHHHHHHHHHHHHHHHH?ST--------------------------TTT?EEEEEE???TT?--S?HHHHHHHHHHHHG--GG?SEEEEE???TTST-TGGGGGSHHHHHHHHHHHHHHHHHH???????????????????????????????????????????SSSSS??EEEEEE?S???HHHHHHHHHHHH-HTT?SEEEE???BS???--??GGGTT??-------SEEEEHHHHHHHHHHHHHHHHHTTT?S?EEEESS??SHHHHHHHHHTTEEEEEESHHHHHHGGGHHHHHHHHHHHHH 4EF9|A PF01182.15_Glucosamine_iso_seed 317 374 !Q:17,21|24,26|28,34|36,37|43,44|55,56|60,61|64,88|92,94|96,100|112,113|115,115|118,118|121,121|133,135|138,145|147,152|154,154|157,192|200,200|202,206|208,208|216,216|226,256|258,270|272,272|274,275|282,284|287,288|293,293|296,298|301,301|303,305|307,307|309,311|313,316|323,325|331,337|342,342|349,349|358,358|360,360|370,370 Q:0,16|22,23|27,27|35,35|38,42|45,54|57,59|62,63|89,91|95,95|101,111|114,114|116,117|119,120|122,132|136,137|146,146|153,153|155,156|193,199|201,201|207,207|209,215|217,225|257,257|271,271|273,273|276,281|285,286|289,292|294,295|299,300|302,302|306,306|308,308|312,312|317,322|326,330|338,341|343,348|350,357|359,359|361,369|371,373 HHHHHHHHHHHHHHHHH-----HH---H-------S?-EEEEE??SHHHHHHHHH--HHH--TG-------------------------GGS--?G-----GGEEEEESEEE?-S?TT?TT?HHHHHHHHTGG---GS----?-??G------G-GB?--??-----------------------------??TTSTTTT?H-----H-HHHHHHH-HHHHHHHTS-------------------------------S-------------S?S--EEEEEE???TT??BTTB?TT--?HH-H---H?S---S-?--SEEEES??-SSSSS?------EEEE?HHHHTT-EEEEEEEE?S-GGGHHHHHH-HHH 1VL1|A PF01183.15_Glyco_hydro_25_seed 28 218 !Q:3,3|7,7|9,13|18,22|27,30|44,44|59,59|67,68|70,71|75,75|88,92|97,99|103,104|106,106|108,115|118,118|123,124|140,140|147,148|151,151|154,154|165,166|172,175|180,180|183,183|186,189|191,198|203,203 Q:0,2|4,6|8,8|14,17|23,26|31,43|45,58|60,66|69,69|72,74|76,87|93,96|100,102|105,105|107,107|116,117|119,122|125,139|141,146|149,150|152,153|155,164|167,171|176,179|181,182|184,185|190,190|199,202|204,217 EEE?GGG?S??---HHHH-----HHTT?--?EEEEEEEETTTEE?TTHHHHHHHHHHTT?EEEEEEE??T--TTS?HHHHHHHHHHTT?????SSSB???EEE??S?S--------SS?TTTT??HHHHHHHHHHHHHHH-HHHHSS??EE-EE?HHHHHHHHTS??TTTTT?--?EEEE?TT?SS????T--------TSSS?SEEEEEEEEEETTE 2J8F|A PF01185.13_Hydrophobin_seed 69 126 !Q:0,2|4,5|12,13|20,30|39,39|43,51|60,60|72,74|82,82|93,94|97,98|100,107|111,117|120,122|125,125 Q:3,3|6,11|14,19|31,38|40,42|52,59|61,71|75,81|83,92|95,96|99,99|108,110|118,119|123,124 ?-?G--GGEEEE??HHHHTS-----------STTHHHHS?TTS?-------?EETTEEEE-EEEEHHHHTTT-??TTTEEEE-TTEEEESSEE--EE??S--------SSS?------BE---ES? 2LSH|A PF01187.13_MIF_seed 6 115 !Q:0,0|9,9|14,14|30,30|32,32|36,36|42,42|44,47|52,52|55,55|67,67|89,90|102,102|106,106 Q:1,8|10,13|15,29|31,31|33,35|37,41|43,43|48,51|53,54|56,66|68,88|91,101|103,105|107,114 ?EEEEEESS?GGGS?TTHHHHHHHHHHHHH?S?GGG?EEEEE?S????BTTB?SS?EEEEEEEESSS?SHHHHHHHHHHHHHHHHHHHT??GGGEEEEEEEE?GGG?EETTEEGG 2WKF|A PF01188.16_MR_MLE_seed 1272 188 !Q:2,4|11,14|16,16|18,18|21,33|38,46|48,56|58,75|77,87|89,89|95,97|102,108|110,110|112,121|123,127|129,130|133,135|137,137|139,144|146,146|148,154|160,160|162,164|166,169|171,171|173,176|179,182|184,184|187,187 Q:0,1|5,10|15,15|17,17|19,20|34,37|47,47|57,57|76,76|88,88|90,94|98,101|109,109|111,111|122,122|128,128|131,132|136,136|138,138|145,145|147,147|155,159|161,161|165,165|170,170|172,172|177,178|183,183|185,186 HH---HHHHHH----H?S-SS-----------?-EEEE-----?---T---------T?--------------?-?H-----------H-HHHHH---HHHH-------G-G----------G?---?S-?EE-??S?T------T?H-------HHHHH-H---H----H-H?---SS?---E-EE? 4HCH|A PF01189.12_Nol1_Nop2_Fmu_seed 10 335 !Q:7,10|15,15|19,20|33,34|37,38|41,41|45,46|52,54|69,70|81,83|86,86|88,100|106,106|109,109|119,119|121,122|124,124|132,132|148,150|155,159|170,176|184,188|195,195|202,203|214,215|228,244|256,258|265,274|283,283|286,287|289,289|293,293|298,314|319,321|325,326|334,334 Q:0,6|11,14|16,18|21,32|35,36|39,40|42,44|47,51|55,68|71,80|84,85|87,87|101,105|107,108|110,118|120,120|123,123|125,131|133,147|151,154|160,169|177,183|189,194|196,201|204,213|216,227|245,255|259,264|275,282|284,285|288,288|290,292|294,297|315,318|322,324|327,333 HHHHHTS????EEEE?TTT??HHHHHHHHHHTT??EE??TT?TTE--EEESS???GGGSTTGGGTSEEE??HHHHTHHHHH???TT?E-------------EEEES?TT?HHHHHHHHH?T--T?EEEEEES?HHHHHHHHHHHHHTT???EEEE---??TTSTHHHHTT?-----?EEEEEEE?????GGGTTT?TTHHHH??TTHHHHHHHH--HHHHHHHHGGGE-----------------EEEEEEEEEES???TTTTHH----------HHHHHHHH?TT??B?SSB?SSSB-----------------SEEE???TTS??SEEEEEE? 2YXL|A PF01191.14_RNA_pol_Rpb5_C_seed 64 95 !Q:1,1|9,10|13,15|27,29|33,44|46,49|52,52|59,64|66,67|70,70|76,82|86,87|93,95 Q:0,0|2,8|11,12|16,26|30,32|45,45|50,51|53,58|65,65|68,69|71,75|83,85|88,92 S?TTSBTTB??EE???HHHHHHHHHHT???TTT------------S????TT?HHHHHH------T??TT?EEEEE???---?TTS??EEEEE??- 1K83|E PF01192.17_RNA_pol_Rpb6_seed 57 63 !Q:1,2|4,4|7,8|23,24|27,27|29,33|35,37|39,44|57,60 Q:0,0|3,3|5,6|9,22|25,26|28,28|34,34|38,38|45,56|61,62 S??S?SS??HHHHHHHHHHHHHH--HH-T?????S???S??---?TTHHHHHHHHTT????EE 1K83|F PF01193.19_RNA_pol_L_seed 218 597 !Q:23,23|36,37|41,43|49,49|60,61|64,64|67,67|77,77|88,89|97,401|403,403|409,409|412,413|428,428|433,435|440,440|443,444|447,449|459,461|463,479|482,526|528,554|565,566|570,578|586,586 Q:0,22|24,35|38,40|44,48|50,59|62,63|65,66|68,76|78,87|90,96|402,402|404,408|410,411|414,427|429,432|436,439|441,442|445,446|450,458|462,462|480,481|527,527|555,564|567,569|579,585|587,596 EEEEETTHHHHHHHHHHHHHHHT?EEEEEEEEEETT??STT???TTBSS?HHHHHHHHTT??EE?TT?SEEEEEEEE?SSEEEEGGGS??BTTBEES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------??S?EEEEE?SS??EEEEEEEEEEESEE?HHHH???SSTT?EE??EE???EEEEEEEEE???S-----------------SS--------------------------------------------?S--------------------------?EEEEEEEEEE?-SSS--------?HHHHHHH-HHHHHHHHHH 1K83|C PF01194.12_RNA_pol_N_seed 49 91 !Q:0,3|6,6|10,14|16,22|35,39|42,51|60,62|74,84 Q:4,5|7,9|15,15|23,34|40,41|52,59|63,73|85,90 ????SS?SSS-????S-------SSSTTTHHHHTS-----SS??--------GGGGGGGS?-?SSSSHHHHHTB------??---TTHHHH 1K83|J PF01195.14_Pept_tRNA_hydro_seed 116 247 !Q:4,7|29,34|38,46|59,59|62,63|66,79|82,84|93,93|95,95|112,118|120,120|133,133|136,136|143,145|147,147|149,149|162,164|172,181|183,186|190,192|201,203|213,213|228,231|233,236|245,245|247,247 Q:0,3|8,28|35,37|47,58|60,61|64,65|80,81|85,92|94,94|96,111|119,119|121,132|134,135|137,142|146,146|148,148|150,161|165,171|182,182|187,189|193,200|204,212|214,227|232,232|237,244|246,246 EEEE????STTTTTSGGGHHHHHHHHHHH------HTT------???EEEGGGTEEEEE-EE--ET--------------TE---EEEEEEES-S?GGGHHHHHHHHHHHTT-----??G-GGEEEEEEETTS?TT?EEEEES???T-T?HHHHHHHHHTTS???SEEEEEE??---?---?S----SSS---THHHHHTS???HHHHHHHHH-HHHHHHHHHHHHTS?---H----HHHHHHHH-H- 3NEA|A PF01196.14_Ribosomal_L17_seed 153 323 !Q:2,2|12,40|43,43|64,80|84,87|89,108|110,140|147,148|154,180|184,194|197,197|203,238|246,253|259,259|261,261|265,266|271,273|275,276|278,278|280,311|313,314|321,322 Q:0,1|3,11|41,42|44,63|81,83|88,88|109,109|141,146|149,153|181,183|195,196|198,202|239,245|254,258|260,260|262,264|267,270|274,274|277,277|279,279|312,312|315,320 HH-HHHHHHHHH-----------------------------HS?EEEEHHHHHHHHHHHHHHHH-----------------HHH----H------------------?-S-------------------------------HHHHHH--HGGGS-----------------------?---SSS----------?SS?BSSSB------------------------------------HHHHHHT--------HHHHH?S-SSS??SEEE?-?S-?B?T--------------------------------T??BEEEEE?? 2ZJQ|K PF01197.13_Ribosomal_L31_seed 163 96 !Q:0,3|6,9|14,15|18,20|27,29|32,46|50,57|60,60|63,69|71,73|76,82|85,85|88,89|91,94|96,96 Q:4,5|10,13|16,17|21,26|30,31|47,49|58,59|61,62|70,70|74,75|83,84|86,87|90,90|95,95 ?-??SS???-HHHH-?TT??-SSSSSS???SS---------------SSS-?---???SS?SS--?????S-?-SS?-?????SS?SS??S?-??S- 2XG2|4 PF01198.14_Ribosomal_L31e_seed 59 86 !Q:0,4|11,11|41,41|43,44|46,49|60,60|63,65|85,85 Q:5,10|12,40|42,42|45,45|50,59|61,62|66,84 ?????EEEEEE?HHHHSSBSSSBHHHHHHHHHHHHHHHHHT?S--S????HHHHHHHHTT?SS???SEEEEEEEEETTTTEEEEE? 1S1I|W PF01199.13_Ribosomal_L34e_seed 52 108 !Q:0,12|16,17|19,20|23,23|29,30|33,34|36,37|43,53|57,62|65,69|76,77|79,79|84,85|94,94 Q:13,15|18,18|21,22|24,28|31,32|35,35|38,42|54,56|63,64|70,75|78,78|80,83|86,93|95,107 ??-?-????----SSS??S??TT?EEEEE??TT--S??EEEEE????????--?SSS???--?TT?????STTTTS--S?TTTT??SSSSSSSS?SHHHHHHHHHHHH 3J39|g PF01200.13_Ribosomal_S28e_seed 38 93 !Q:0,10|13,13|15,18|22,24|28,32|50,54|56,56|65,67|70,72|74,74|77,80|82,91 Q:11,12|14,14|19,21|25,27|33,49|55,55|57,64|68,69|73,73|75,76|81,81|92,92 ????-------SS?E----EEE---EEE?????SSSSEEEEEEEESSSSS?----S?EEEEEEES???TT--?E-EE?---S??????-???S 2XZM|1 PF01201.17_Ribosomal_S8e_seed 93 357 !Q:0,2|4,7|12,12|15,16|18,21|23,26|31,90|93,100|103,107|113,138|142,142|144,144|148,177|179,179|182,182|199,200|205,205|208,208|217,218|221,221|225,227|239,239|241,241|245,246|260,260|268,297|303,304|309,310|321,322|327,327|329,329|333,347|350,352|356,356 Q:3,3|8,11|13,14|17,17|22,22|27,30|91,92|101,102|108,112|139,141|143,143|145,147|178,178|180,181|183,198|201,204|206,207|209,216|219,220|222,224|228,238|240,240|242,244|247,259|261,267|298,302|305,308|311,320|323,326|328,328|330,332|348,349|353,355 ???B???-SSSB?SS??B????S?-??GGGB???-----------------------------------------------------????BB--------SS---??EEEEE-------------------------?SSS?E-EEE------------------------------E?SB?EEEEEETTTTEEEEEE??EEEE?SS?HHHHHTTB??TT?EEE???HHHHHHHHHHH?S?STT??HHHHTTTTHHHHH?BSTTTBH------------------------------HHHHH??SGGG??HHHHHHHHHT??EEEE?S?HHH---------------HS???EEE? 2XZM|2 PF01202.17_SKI_seed 98 257 !Q:3,3|17,17|23,23|26,26|28,29|31,34|40,43|45,45|52,52|55,55|68,70|72,73|81,85|91,92|95,96|103,105|112,124|129,129|133,136|143,162|164,164|168,176|179,179|181,184|186,187|201,202|204,215|217,217|219,220|222,230|232,244|256,256 Q:0,2|4,16|18,22|24,25|27,27|30,30|35,39|44,44|46,51|53,54|56,67|71,71|74,80|86,90|93,94|97,102|106,111|125,128|130,132|137,142|163,163|165,167|177,178|180,180|185,185|188,200|203,203|216,216|218,218|221,221|231,231|245,255 TTS?HHHHHHHHHHHTT?EEEEH-HH-H--H----HHHHT----S?HHHHHH-HH-HHHHHHHHHHHH---H--HHHHTSS-----SEEEE??TT--GGGSHH---HHHHHH-------------HHSE-EEE????HHHHHS??--?-????----?---??S-SSS??------?HH-H----H--HHHHHHHHHHHHH--H-----?------S-E--E-???-????H-------------HHHHHHHHHHH? 1ZYU|A PF01204.13_Trehalase_seed 20 629 !Q:11,11|16,18|32,42|53,90|93,94|97,99|109,110|114,119|121,123|126,126|129,131|134,143|146,147|152,152|154,154|171,171|174,185|204,205|215,217|219,220|232,242|244,244|269,270|281,281|283,283|285,286|290,293|295,296|298,299|313,313|315,320|323,323|339,340|342,342|349,350|353,356|361,361|367,367|383,387|395,408|439,440|447,458|461,464|476,476|478,478|482,490|505,507|512,512|516,521|531,531|547,550|573,579|582,582|587,594|598,602|604,605|608,610|613,613 Q:0,10|12,15|19,31|43,52|91,92|95,96|100,108|111,113|120,120|124,125|127,128|132,133|144,145|148,151|153,153|155,170|172,173|186,203|206,214|218,218|221,231|243,243|245,268|271,280|282,282|284,284|287,289|294,294|297,297|300,312|314,314|321,322|324,338|341,341|343,348|351,352|357,360|362,366|368,382|388,394|409,438|441,446|459,460|465,475|477,477|479,481|491,504|508,511|513,515|522,530|532,546|551,572|580,581|583,586|595,597|603,603|606,607|611,612|614,628 TSSSSHHHHHT?EESS?--HHHHHHHHHHHHT?------????HHHHHHHHEE?--------------------??????????-------TT??HH---HHHHHHHHH--HEE----??S???TT?SB???SS---------?EE??BTTB?S?BHHHHHHHHHHHHHTT?HH------------HHHHHHHHHHHHHHHHSS??SBSBGGGTT???S??HHHHHHHHHHH-----------H?THHHHHHHHHHHHHHHHHTTTGGG??TTEEETTEEE?T-T??EEE????S??S??GGGHHHHHHHHHT?T------TS?HHHHHHHHHHHHHTS??S?GGGBSS--TT?---GGGB?GGGEE?HHHHHHHHHHHHHHH-----HHHHHTT?-------------HHHHHHHHHHHHHHHHHHHHHSEETTTTEE??EETTTT------------EE????BGGGGHHHHTT?S?HHH---------HHHHHHHHHHHTEE---TTEE?SBS??---?SSSSSTTEE?HHHHHHHHHHHHHTT?---HHHHHHHHHHHHHHHHHHHHHH----???BS?EETT--------TSS??--?S??SS???BS?HHHHHHHHHHHHHHS 2WYN|A PF01205.14_UPF0029_seed 179 174 !Q:12,13|16,16|18,23|36,36|39,43|46,48|53,60|62,62|66,102|106,106|110,110|120,120|126,129|131,137|139,140|146,147|150,151|153,156 Q:0,11|14,15|17,17|24,35|37,38|44,45|49,52|61,61|63,65|103,105|107,109|111,119|121,125|130,130|138,138|141,145|148,149|152,152|157,173 ETTEEEEEEEEE??HH-H------HHHHHHHHHHHH?TT----?SB-??EEEE?-----?-S?SSS----------------------------------???EEE?TTS?TTSSSHHHH-HHHHH----H-------T??SEEEE??EE??S????HHHHHHHHHHHHHHHHT 2CVE|A PF01206.12_TusA_seed 195 103 !Q:4,4|7,8|23,25|28,33|36,38|40,44|50,50|54,54|66,68|73,74|77,87|90,91|93,93|95,95|100,100|102,102 Q:0,3|5,6|9,22|26,27|34,35|39,39|45,49|51,53|55,65|69,72|75,76|88,89|92,92|94,94|96,99|101,101 EEEE?SS??SSHHHHHHHHHHHT?-?TT-----?EE---E-----EEESS?THH-HHHHHHHHHSS?-?EEEE--EE----------?SS--S?E-EEEE-E? 1DCJ|A PF01207.12_Dus_seed 17 378 !Q:2,5|9,10|22,48|58,58|62,64|72,72|81,81|84,85|93,93|95,95|109,109|112,112|120,138|154,154|156,156|159,159|167,167|170,173|176,176|189,190|199,206|212,212|214,214|217,218|229,229|231,233|235,235|242,243|246,248|259,260|277,281|286,286|288,295|299,302|313,326|336,339|344,347|358,366|368,370 Q:0,1|6,8|11,21|49,57|59,61|65,71|73,80|82,83|86,92|94,94|96,108|110,111|113,119|139,153|155,155|157,158|160,166|168,169|174,175|177,188|191,198|207,211|213,213|215,216|219,228|230,230|234,234|236,241|244,245|249,258|261,276|282,285|287,287|296,298|303,312|327,335|340,343|348,357|367,367|371,377 EE?-??TTT??HHHHHHHHHTS??-------------------------SEEEEEEEE?SSS???HHHHHHH?GGGGGTTB?TT??BEEEEEE?S?HHHHHHHHHHHHH-TT?SSEEEEE???????????????????HHHHHHHHHHHHHHS?T-TS?EEEEEES?SS--??TT-HHHHHHHHHHTT-?SEEEEESS-------?STTTT?G-GG??HHHHHHHHHH?S---S?EEEESS??SH---HHHHHHHHHH??SEEEESTHHHHSTTHH-----HHHH-H??????--HHH----HHHHHHHHHH?????--???????SHHHHHHHH----HTTT--?-THHHHHHHHH??---????T---THHHHHH 1VH7|A PF01208.12_URO-D_seed 173 590 !Q:0,12|21,25|27,36|38,39|41,42|45,45|59,59|69,69|71,71|87,90|92,92|95,103|105,105|115,116|120,120|122,122|125,133|138,141|143,155|157,159|163,165|168,169|171,186|190,193|195,196|210,213|216,220|223,226|229,229|236,239|252,253|255,256|258,258|267,272|274,274|281,281|299,299|303,303|305,307|313,317|324,324|328,331|341,341|349,349|354,365|369,370|375,375|379,383|385,385|387,387|394,395|397,400|403,404|406,408|410,410|413,433|437,444|446,449|454,467|470,473|476,494|498,502|506,507|509,509|511,511|516,519|521,521|528,534|543,549|552,554|558,558|562,562|566,571|575,575 Q:13,20|26,26|37,37|40,40|43,44|46,58|60,68|70,70|72,86|91,91|93,94|104,104|106,114|117,119|121,121|123,124|134,137|142,142|156,156|160,162|166,167|170,170|187,189|194,194|197,209|214,215|221,222|227,228|230,235|240,251|254,254|257,257|259,266|273,273|275,280|282,298|300,302|304,304|308,312|318,323|325,327|332,340|342,348|350,353|366,368|371,374|376,378|384,384|386,386|388,393|396,396|401,402|405,405|409,409|411,412|434,436|445,445|450,453|468,469|474,475|495,497|503,505|508,508|510,510|512,515|520,520|522,527|535,542|550,551|555,557|559,561|563,565|572,574|576,589 ??---------??HHHHHHTT-??-?S----------S??B??TT?SSTTSHHHHHHHH-HHSSHHHHT-T?HHHHHHHHHTGGGTS?--?S?EE??-----??T-THHHHTTTS-?EEE?S-SS------?--EEES----S???----------S---HHH---HH--T?-----------????TTT----T--THHHHHHHHHHHH----HT-----TT----SS?EEEEEE---?HHHHHHHHHHSS??S--S?HHHHHHHT------T?HHHHHH-HHHHHHHHHHHHHHHHH-HTT?S---EEEEE?----TTGGGS?HHH----HHHHTHHHH-HHHHHHS?SEET------------TEE??EEEE?TTT-----T-T-THHHHH--T----TS-?S---E-EE?-------------------?TTS-------?H----HHHH--------------HH----HT-------------------TTS-----EEE??B?G-GGGG----S?HHHHHH-------HHHHHHTT-------TT---TSS?EEB?BSS?---??TTS?HHHHHHHHHHHHHH 1R3Q|A PF01209.13_Ubie_methyltran_seed 5 260 !Q:0,41|49,50|52,57|64,64|67,67|79,94|102,102|118,123|130,136|138,138|140,140|142,142|151,151|155,155|157,157|183,183|198,209|211,211|213,213|216,224|232,232|239,239|244,253 Q:42,48|51,51|58,63|65,66|68,78|95,101|103,117|124,129|137,137|139,139|141,141|143,150|152,154|156,156|158,182|184,197|210,210|212,212|214,215|225,231|233,238|240,243|254,259 ---?????---?????????--------???-????????--HHHHHHT??S?----?EEEEET?TT?HHHHHHGGGSS----------------EEEEEES?HHHHHHHHHHHHHTT??----SEEEEE???????S?T-T?EEEEEEES?GGG?S?HHHHHHHHHHHEEEEEEEEEEEEEB?SSHHHHHHHHHHHH------------H-H?TT?----????BHHHHHH-HHHHHT?EEEE----------EEEEEE 3BKX|A PF01210.18_NAD_Gly3P_dh_N_seed 44 208 !Q:0,0|5,6|22,31|36,36|38,38|40,48|60,60|68,72|74,74|81,81|89,90|95,97|112,118|121,121|126,136|138,141|144,153|157,157|167,167|169,173|181,182|190,191|199,201|203,203 Q:1,4|7,21|32,35|37,37|39,39|49,59|61,67|73,73|75,80|82,88|91,94|98,111|119,120|122,125|137,137|142,143|154,156|158,166|168,168|174,180|183,189|192,198|202,202|204,207 ?EEEE??SHHHHHHHHHHHTTT--------??EEEE?S?H---------HHHHHHHHHSS-BTTTBTT-????T-TEEEES?HHHHHTT??EEEE???HHHHHHHHHHHGGG?-----?TT?EEEE--------???S?---BT----------TTB?HHHHHHHHH?S??---EEEEESS??HHHHHTT??EEEEEEE---S?HHHH 1EVY|A PF01212.16_Beta_elim_lyase_seed 53 575 !Q:1,1|3,3|6,8|10,13|24,24|26,32|36,36|38,44|55,65|67,96|99,102|105,106|108,109|111,124|127,127|129,129|139,142|149,150|156,157|160,162|169,170|174,174|181,182|185,185|190,190|192,194|197,199|202,202|206,210|215,215|217,217|224,224|230,230|233,243|261,263|265,265|280,288|293,293|299,300|309,309|315,316|326,327|330,331|343,344|347,348|356,356|372,372|378,394|396,397|413,413|424,425|428,431|438,441|443,444|448,453|455,455|458,459|471,473|477,477|481,481|495,495|498,498|503,508|513,513|515,515|519,521|524,529|531,532|534,541|545,550|552,554|556,557|561,564 Q:0,0|2,2|4,5|9,9|14,23|25,25|33,35|37,37|45,54|66,66|97,98|103,104|107,107|110,110|125,126|128,128|130,138|143,148|151,155|158,159|163,168|171,173|175,180|183,184|186,189|191,191|195,196|200,201|203,205|211,214|216,216|218,223|225,229|231,232|244,260|264,264|266,279|289,292|294,298|301,308|310,314|317,325|328,329|332,342|345,346|349,355|357,371|373,377|395,395|398,412|414,423|426,427|432,437|442,442|445,447|454,454|456,457|460,470|474,476|478,480|482,494|496,497|499,502|509,512|514,514|516,518|522,523|530,530|533,533|542,544|551,551|555,555|558,560|565,574 E?S?SS---S-???EEHHHHHHHH-T??-?-?-SSS?H-------HHHHHHHHHH-----------H------------------------------HH???-EE--E--E--------------ES-S-HHHHHHHHH----HHHHHH--HHHTT??SS?--EEEESS??HHH-HHHHHH--TT?EEEE?B--?GG---GG?TTS---??TTTT?B?HHHHHH-HHHHH?GG-----------GEEEEEEESSBTTTTSB???H-HHHHHHHHHHHHHT-------??EEEE?TTHHH--HHHHHHHH?GGGTT??HHHHHHHHG--GG-?SEEEEETTSTT??SS?-EEEEESS?HHHHHHHHHHHHHHT?STTTT-----------------T??HHHHHHHHHHHHHTT?HHHHHHHHHH--HH----HHHHHH----H--HTT----??B?SS??SSEEEEESTTT--?TTS?GGG?HHHHHHHHHHHHH?EE?EEES------HHHH?B?TTT--?SB???---S??E--------EEE------E-??T--TSS---?HHHHHHHHHH 2VMP|A PF01213.14_CAP_N_seed 6 381 !Q:0,86|88,88|114,114|142,145|148,149|196,197|199,199|226,226|255,258|261,263|265,265|269,380 Q:87,87|89,113|115,141|146,147|150,195|198,198|200,225|227,254|259,260|264,264|266,268 ---------------------------?--------------------------------????-----------------------S?HHHHHHHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHHHHHHHHHHB????HH--HHHHHHHHHHHHHHHHHHHHHTTTTSTTHHHHHHHHTTGGGGGGGG??S?HHHHHHHHHHHHHHHHHHHHHHHTTT?HHHHHHHHHHHHHHHHHHHHHHHHSTTS????TT?--B?SSS??-----------------------?-------------------------------------------------------------------------------------- 1S0P|A PF01214.13_CK_II_beta_seed 66 310 !Q:0,0|9,9|12,12|15,19|36,37|51,93|97,100|129,133|141,141|145,145|147,148|155,155|157,157|160,161|165,165|171,171|177,177|181,182|185,187|212,213|216,217|219,221|223,293|295,303 Q:1,8|10,11|13,14|20,35|38,50|94,96|101,128|134,140|142,144|146,146|149,154|156,156|158,159|162,164|166,170|172,176|178,180|183,184|188,211|214,215|218,218|222,222|294,294|304,309 ?HHHHHHTS-TT?TT?????HHHHHSTTTTTTGGGT--SSSHHHHHHHHTT??????---------------------------------????TTH----HHHHHHHHHHHHHHHHHHHTTSHHHHHH-----HHHHHHT-TTT?B??BGGGTS?B?EE--EES?SSTTS?BEEEE?TTT??EE??-SSTTSTTSBGGGTTTTHHHHHHHH?-GG--G???S----------------------------------------------------------------------?S?????----EETTEE 1QF8|A PF01215.14_COX5B_seed 4 138 !Q:0,36|38,40|45,46|60,61|64,65|67,75|79,79|94,95|99,99|101,103|113,113|116,116|120,121|128,137 Q:37,37|41,44|47,59|62,63|66,66|76,78|80,93|96,98|100,100|104,112|114,115|117,119|122,127 ??????????---??????-?????????????????B???HHHH??HHHHHHHHHHHTT??TT??S?????-???SSS?EEEEESSSEEEEEE??STT?S-??EEEEEESSS?EE?TTT??EEEEEE-----????? 1V55|F PF01216.12_Calsequestrin_seed 3 386 !Q:0,33|35,37|41,42|53,53|62,65|112,113|129,130|132,133|148,148|153,154|165,166|169,169|175,175|177,177|180,180|198,198|203,204|213,214|217,217|222,222|225,225|228,228|231,231|236,237|249,249|251,251|256,257|267,268|278,279|299,299|302,302|305,306|311,311|315,315|328,329|333,333|348,351|355,358|372,385 Q:34,34|38,40|43,52|54,61|66,111|114,128|131,131|134,147|149,152|155,164|167,168|170,174|176,176|178,179|181,197|199,202|205,212|215,216|218,221|223,224|226,227|229,230|232,235|238,248|250,250|252,255|258,266|269,277|280,298|300,301|303,304|307,310|312,314|316,327|330,332|334,347|352,354|359,371 ------------------------??????????S???EEE??TTTHHHHHHH?SEEEEEEE????SSHHHHHHHHHHHHHHHHHHHHHGGGTEEEEEEETTTTHHHHHHHT??SSSEEEEEETTEEEE??S??SHHHHHHHHHHHHS?SEEE??SHHHHHHHHH??SS?EEEEE?S?TT?HHHHHHHHHHHHHTTTS?EEEE??HHHHHHHT??TT?EEEE?TT?SS?EE?SSSS??HHHHHHHHHHT?S?SEEE??GGGHHHHHS??SSSEEEEEE??TTSHHHHHHHHHHHHHHHT?TT?TT??EEEE?GGG?GGGHHHHHHHHT??TTS?EEEEEETTTTEEEE????TTS????HHHHHHHHHHHHH?????????????? 3TRQ|A PF01217.15_Clat_adaptor_s_seed 7 165 !Q:0,0|11,12|19,20|22,24|29,29|43,44|48,64|72,73|91,92|96,96|117,117|119,119|142,142|146,149|163,164 Q:1,10|13,18|21,21|25,28|30,42|45,47|65,71|74,90|93,95|97,116|118,118|120,141|143,145|150,162 ?EEEEEEEETT??EEEEEE?-S???HHHH-HHHHHHHHHHHTT??SSS----------------?SEEEETT--EEEEEEEETTEEEEEEE?-TTS?HHHHHHHHHHHHHHHHHHTT-S?BTTHHHHTHHHHHHHHHHHEET-TEE????HHHHHHHHTTTTS?? 2JKT|I PF01218.13_Coprogen_oxidas_seed 93 370 !Q:19,22|25,25|27,29|31,35|37,41|48,51|53,54|57,61|72,72|87,127|146,146|156,157|160,162|164,164|166,168|171,172|184,184|187,193|212,213|248,251|253,256|258,261|290,293|315,315|326,328|337,337|342,343|346,350|366,369 Q:0,18|23,24|26,26|30,30|36,36|42,47|52,52|55,56|62,71|73,86|128,145|147,155|158,159|163,163|165,165|169,170|173,183|185,186|194,211|214,247|252,252|257,257|262,289|294,314|316,325|329,336|338,341|344,345|351,365 HHHHHHHHHHHHHHHHHHH----HH-H---S-----S?--??EEEEEE?---T--TS-----EEEEEEEEES?SSEEEEEEEEEEEE???????????--????-----???----------------EEEEEEEEEEEEESSTTS?EEEEEEEEE--EE---E?T---TS??EEEEEEEEEEE?SS?-----?HHHHHHHHHHHHHHHGGG-?TTHHHHHHHHHHHHSEEGGGTEESSSEEEEEEEE?---S----S?---HHHHHHHHHHHHHHHHHHHHHHHHHHTT????HHHHHHHHHHHHHHHHHHHHT?HHHHHHHHTT-??HHHHGGGS?SEEE??TT-????TTSHHHHHHHTHHHH???? 1TK1|A PF01219.14_DAGK_prokar_seed 186 112 !Q:8,8|35,45|75,79|81,81 Q:0,7|9,34|46,74|80,80|82,111 HHTHHHHH-HHHTTTTTHHHHHHHHHHHHHHHHHH?------????SHHHHHHHHHHHHHHHHTHHHHHHHHHTT??-??S?TTSHHHHHHHHHHHHHHHHHHHHHHHHHHH 2KDC|A PF01220.14_DHquinase_II_seed 191 173 !Q:0,0|7,7|15,15|23,26|37,38|44,45|47,49|56,56|70,74|78,81|87,87|94,94|100,103|109,111|113,118|126,126|131,132|137,144|151,151 Q:1,6|8,14|16,22|27,36|39,43|46,46|50,55|57,69|75,77|82,86|88,93|95,99|104,108|112,112|119,125|127,130|133,136|145,150|152,172 ?EEEEEE?TTGGGTT?SSGGGTT?-??HHHHHHHHHH--HHHHT--T--?EEEEEE?SSHHHHHHHHHHT-----TTT--??EEEEE?TTHHHH?HHHHH----HHHHH---T?-?---EEEEESS?GGGS-?GGGS------??SSGGGS-SEEEESSTTHHHHHHHHHHHH 3N87|A PF01221.13_Dynein_light_seed 75 114 !Q:0,10|12,13|19,19|21,21|24,25|39,40|42,45|47,52|54,55|58,58|72,72|74,74|76,77|85,86|91,91|101,101|104,105|112,113 Q:11,11|14,18|20,20|22,23|26,38|41,41|46,46|53,53|56,57|59,71|73,73|75,75|78,84|87,90|92,100|102,103|106,111 ?-----?--??S?-EEEEE?S?SH--HHHHHHHHHHHHH--H----H??---?S--HH-HHHHHHHHHHHHH?S?B??EEESSTT??STTT?SEEEEEEET-TE--EEEEEE?? 3ZKF|A PF01223.18_Endonuclease_NS_seed 59 377 !Q:1,1|4,4|12,13|25,25|29,69|73,75|77,78|82,82|85,85|87,89|98,105|112,112|114,119|122,123|125,125|136,136|143,143|150,151|154,162|176,190|194,194|203,204|208,208|212,251|262,263|268,269|284,297|310,312|315,329|333,345|348,349|357,362|365,368|374,374 Q:0,0|2,3|5,11|14,24|26,28|70,72|76,76|79,81|83,84|86,86|90,97|106,111|113,113|120,121|124,124|126,135|137,142|144,149|152,153|163,175|191,193|195,202|205,207|209,211|252,261|264,267|270,283|298,309|313,314|330,332|346,347|350,356|363,364|369,373|375,376 E?SS?EEEEETT--TTEEEEEEEEE?TTT???????---------------------------------?GGG???B??TTS?GG-G???HHHHTTTT-------?EEEESS?G------GG??S?HHHHHHTTBG-GGEEEE?IIIIIT--TH---------HHHHHHHHHHHHT---------------TSS?EEEEEEEE??EEE?TTS?---------------------------------------EEEEEEEETT--TTEE??SEEEEEEEEEEETT--------------EEEEEEEEEESS???TT?-------------?GGG-------------GB??HHHHHHH------HT--??TTTTS?GG 4GTW|A PF01225.20_Mur_ligase_seed 236 141 !Q:3,3|14,17|21,21|29,29|32,46|50,50|53,54|57,57|66,67|73,78|85,85|87,93|98,98|100,100|102,103|106,110|115,115|122,123|125,125 Q:0,2|4,13|18,20|22,28|30,31|47,49|51,52|55,56|58,65|68,72|79,84|86,86|94,97|99,99|101,101|104,105|111,114|116,121|124,124|126,140 EEE-EETTTSTTHH----HHH-HHHHHTT?EE---------------EEE?SS??HH-HHHHHHTT-?EEESS?----?GGGGTT?S-------EEEE?T-T??TT----?HHHH-HHHHTT??E-EEHHHHHHHHHTTSE 2WTZ|A PF01226.12_Form_Nir_trans_seed 190 366 !Q:0,22|52,65|69,69|71,80|91,91|104,106|113,113|122,126|128,128|157,159|164,172|177,184|196,201|204,205|207,213|215,229|253,253|255,256|259,260|279,281|293,299|303,303|307,308|317,324|331,331|333,333 Q:23,51|66,68|70,70|81,90|92,103|107,112|114,121|127,127|129,156|160,163|173,176|185,195|202,203|206,206|214,214|230,252|254,254|257,258|261,278|282,292|300,302|304,306|309,316|325,330|332,332|334,365 ???????????-????---????HHHHHHHHHHHHHHHHHHHHHHHHHHTTT--------------TSS?H----------HHHHHHHHHH-HTHHHHHHHHHT???TTTTHH-HHHHHTTT?--??H-HHHTTTHHHHHHHHHHHHHHHHHHHHHH---TGGG---------TTTT--------HHHHHHHHHHH------HT--T------?S-?-------------HHHHHHHHHHHHHHHHHHHHHHT-T??SH--HHHHHTTHHHHHHHHHTT???HHHHHHHHHHH-------HHH-HHH??HHHHHHTT------??GGGGTT?S-HHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHH 4FC4|A PF01227.17_GTP_cyclohydroI_seed 104 220 !Q:9,9|14,15|24,24|34,34|41,41|44,45|47,49|54,59|61,62|65,73|75,88|91,92|108,109|114,114|122,125|127,127|131,132|149,149|165,165|167,168|186,186|189,190|193,193|207,207|219,219 Q:0,8|10,13|16,23|25,33|35,40|42,43|46,46|50,53|60,60|63,64|74,74|89,90|93,107|110,113|115,121|126,126|128,130|133,148|150,164|166,166|169,185|187,188|191,192|194,206|208,218 HHHHHHHHH-HHHT??TTSGGGTT-HHHHHHHHH-HHHTGG-GG??H---HHHT------T??EE?-------?S------------??SE--EEEEEEEEEEEETTT??EEEE-EEEEEEE-?--S-SEE??HHHHHHHHHHHHSSEE?HHHHHHHHHHHHHHH-H??SEEEEEEEEEEHHHHSS-TT??TT?EEEEEEEEEHHHH?HHHHHHHHHHT? 4IQI|A PF01228.16_Gly_radical_seed 141 176 !Q:0,1|5,6|10,17|19,19|25,25|28,29|34,34|36,36|39,39|44,45|49,50|52,52|57,57|59,59|61,69|71,71|85,92|95,96|101,127|130,130|135,136|138,144|153,153|157,159|162,162|166,166|172,172 Q:2,4|7,9|18,18|20,24|26,27|30,33|35,35|37,38|40,43|46,48|51,51|53,56|58,58|60,60|70,70|72,84|93,94|97,100|128,129|131,134|137,137|145,152|154,156|160,161|163,165|167,171|173,175 ??STT??STT-----???S?HHHHH-HH--HHTS?G-GG?TTEE??EEE--E?HHHH?S-S---------H-HHHHHHHHHHHHH--------HH??BTTB?-----------------------???EE-EEEE??H-------HHHHHHHH?GGG--?TT?EEE?SSSEE-EGG 2Y8N|A PF01229.12_Glyco_hydro_39_seed 4 547 !Q:0,1|5,6|9,12|15,16|19,23|26,28|31,35|38,38|40,40|61,63|67,67|69,69|77,77|92,93|108,108|111,112|115,116|118,118|125,126|135,135|137,137|140,140|160,160|167,168|174,174|185,185|189,189|205,205|208,209|214,223|229,229|245,249|256,257|259,264|267,271|273,274|294,294|297,298|304,310|312,312|314,314|319,319|326,327|336,337|346,346|349,352|357,357|361,363|368,376|379,379|381,382|384,384|390,392|396,396|408,410|412,413|425,427|430,430|434,434|442,448|450,451|453,455|464,466|468,468|484,484|494,495|498,499|512,513|519,520|522,522|534,534|546,547 Q:2,4|7,8|13,14|17,18|24,25|29,30|36,37|39,39|41,60|64,66|68,68|70,76|78,91|94,107|109,110|113,114|117,117|119,124|127,134|136,136|138,139|141,159|161,166|169,173|175,184|186,188|190,204|206,207|210,213|224,228|230,244|250,255|258,258|265,266|272,272|275,293|295,296|299,303|311,311|313,313|315,318|320,325|328,335|338,345|347,348|353,356|358,360|364,367|377,378|380,380|383,383|385,389|393,395|397,407|411,411|414,424|428,429|431,433|435,441|449,449|452,452|456,463|467,467|469,483|485,493|496,497|500,511|514,518|521,521|523,533|535,545 ??EEE??SS?--?SB??GG-----GG---SE-----EE?S?GGGGGBHHHHHHHHHHHHHS???EEE?S?TTSTTTT?EEEEEETTEEEEEE??HHHHHHHHHHHHTT?EE??EE??B?GGGBSS??EETTTTEE?S?BS?HHHHHHHHHHHHHHHHHHH?HHHHTT??EEESS?TTSTTTSGGG?HHH-HHHHHHHHHHHHHHH?TT??EEEE----------EEESS?THHHHHHHHHHHHHT-????EEEEEE??B??????SS?????B??THHHHHHHHHHHHHHHTSS?TT??EEEEE-------E?S?SSTT?GGGGSH--HHHHHHHH--HHHHGGGT?SE----EEES?SBS???TTSS?-------?SS?S??S?SEETT---TEE?HHHHHHHHGGG?-?S--EEEEEETTEEE---EE?TTS?EEEEEEE----???S??S???EEEEEEEE--?S?SBEEEEEEEESSSSS?HHHHHHHTT??SS??HHHHHHHHHHSS?-EEEEE??B?BTTEEEEEEEE?TTEEEEEEEEE?- 2BFG|A PF01230.18_HIT_seed 26 127 !Q:4,6|11,11|19,19|22,22|35,41|45,46|48,51|73,95|98,98|111,112|116,117|125,126 Q:0,3|7,10|12,18|20,21|23,34|42,44|47,47|52,72|96,97|99,110|113,115|118,124 TTSS???EEEE?SSEEEEE?SS?SSSEEEEEEESS-?--???GGG??G----GGHHHHHHHHHHHHHHHHHTT?----------------------TT?EEEEEEEHHHHT??SSS??EEEEESS?? 4EGU|A PF01231.13_IDO_seed 39 639 !Q:0,6|10,10|18,19|22,28|30,30|40,42|49,61|65,65|67,67|74,74|76,80|84,90|94,94|118,120|122,158|161,161|177,178|181,182|193,197|203,208|210,210|212,212|217,218|222,223|229,229|231,231|261,261|264,264|266,267|295,296|309,310|314,314|317,318|321,321|323,323|327,343|345,348|351,351|354,354|356,359|361,364|368,368|380,381|384,384|387,431|434,449|462,462|475,509|511,512|521,522|524,527|561,618|637,637 Q:7,9|11,17|20,21|29,29|31,39|43,48|62,64|66,66|68,73|75,75|81,83|91,93|95,117|121,121|159,160|162,176|179,180|183,192|198,202|209,209|211,211|213,216|219,221|224,228|230,230|232,260|262,263|265,265|268,294|297,308|311,313|315,316|319,320|322,322|324,326|344,344|349,350|352,353|355,355|360,360|365,367|369,379|382,383|385,386|432,433|450,461|463,474|510,510|513,520|523,523|528,560|619,636|638,638 ?-?????SSS?BTTTBTS?-SS??????-G-GGHHHHHHH---HTHHHH-------------HHT-T?HHHHHH-H?????STT-?----?SHH-HHHHHHHHHHHHHHHHHHTTSSS???S-------------------------------------EE?HHHHHHHHHHHHHHT??SS??HHHHTTSSEE-----ESSTT------S?S?GGGE--EES??SSTTS?H-HHHHHHHHHHHHHHHHHHTTHHHHHHHHH-TT?H--HHHHHHHHHHHHHHHHHHHHHTTHHHH??HHHHHHTHHHHT??BSS?GG--GT-T?BEE-----------------T----TT?SS?B?---B????GGG?HHHHHHHHHTT??SS?SS---------------------------------------------SH----------------HHHHHHHHGGGS?HHHHHHHHHHHT-----------------------------------S??HHHHHHTT??H----HHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHT????????-------------------------------------?????????????THHHHHHHHHHHHHHHHT?S 2D0T|A PF01232.18_Mannitol_dh_seed 16 172 !Q:6,7|27,28|31,31|38,38|45,45|56,56|62,63|65,68|70,73|78,79|89,90|103,104|109,111|116,116|125,125|137,137|141,142|160,163|168,168|171,171 Q:0,5|8,26|29,30|32,37|39,44|46,55|57,61|64,64|69,69|74,77|80,88|91,102|105,108|112,115|117,124|126,136|138,140|143,159|164,167|169,170 EEEEEE??SHHHHHTHHHHHHHHHTTT??TT?EEEEEE?STTHHH-HHHHHHTTTT?EEEEE??S----S????EEEE??EEEEEEGGG?-HHHHHHHHTSTT??EEEE???TTTT?EETTTTEE?TTSHHHHHHHH?TTS??SHHHHHHHHHHHHHHTT????EEEE?SS? 4IM7|A PF01233.14_NMT_seed 6 164 !Q:0,0|5,8|13,13|16,20|28,29|32,32|50,50|58,60|69,70|73,74|87,88|104,105|120,120|124,124|128,128|145,147|155,156|158,160 Q:1,4|9,12|14,15|21,27|30,31|33,49|51,57|61,68|71,72|75,86|89,103|106,119|121,123|125,127|129,144|148,154|157,157|161,163 ?EESS????GGGS?SS?????TTEEEEE??TT?HHHHHHHHHHHHHHSSS?TTSSEEE???HHHHHHHS??TT??GGGEEEEEETTT??EEEEEEEEEEEEEET--TEEEEEEEEEEEEE?GGG?SSS?HHHHHHHHHHHHHTTT???EEEEESS??S???EEE 2WUU|A PF01234.12_NNMT_PNMT_TEMT_seed 7 289 !Q:0,11|17,17|32,33|39,40|49,52|61,61|63,64|72,72|75,76|86,86|95,95|109,109|112,115|128,132|134,136|151,152|156,157|165,167|170,170|172,176|178,178|181,182|191,191|196,196|227,228|237,237|240,244|267,268|272,273|277,279 Q:12,16|18,31|34,38|41,48|53,60|62,62|65,71|73,74|77,85|87,94|96,108|110,111|116,127|133,133|137,150|153,155|158,164|168,169|171,171|177,177|179,180|183,190|192,195|197,226|229,236|238,239|245,266|269,271|274,276|280,288 ????????????GGGGB?HHHHHHHHHSTTTT??SSTTS--HHHHHHHH----HHHHHHTS?S??SEEEETT?TT??GGGTTGGGS?SEEEEEES?HHHHHHHHHHHTT?TT????HHHHHHHHHHHT-----S???HHHHHHHHHHHEEE--EEE??TTSSSTT--?SS?S-----S?SS--EEEEEEES?GGGS?SSHHHHHHHHHHHHTTEEEEEEEEEEEEES??EEEEBTEE-EE?????HHHHHHHHHHTTEEEEEEEEEE??GGG??SSB???EEEEEEEEE 3KQW|A PF01237.13_Oxysterol_BP_seed 149 763 !Q:9,11|14,15|17,17|21,21|23,25|41,41|43,43|45,46|54,56|59,60|67,67|69,69|72,72|75,75|77,77|89,89|108,109|111,112|116,118|121,121|128,130|133,136|140,141|149,173|191,191|193,207|221,221|224,225|230,236|239,240|243,245|250,338|340,349|355,360|365,365|370,371|376,376|385,396|399,399|407,408|410,414|417,419|421,421|425,426|429,437|442,443|447,448|453,460|463,463|467,467|470,471|479,479|489,568|572,572|582,588|590,602|604,612|614,623|625,626|645,645|668,681|686,693|701,701|705,706|710,715|717,719|722,722|734,735|738,738|742,742|751,751|754,757 Q:0,8|12,13|16,16|18,20|22,22|26,40|42,42|44,44|47,53|57,58|61,66|68,68|70,71|73,74|76,76|78,88|90,107|110,110|113,115|119,120|122,127|131,132|137,139|142,148|174,190|192,192|208,220|222,223|226,229|237,238|241,242|246,249|339,339|350,354|361,364|366,369|372,375|377,384|397,398|400,406|409,409|415,416|420,420|422,424|427,428|438,441|444,446|449,452|461,462|464,466|468,469|472,478|480,488|569,571|573,581|589,589|603,603|613,613|624,624|627,644|646,667|682,685|694,700|702,704|707,709|716,716|720,721|723,733|736,737|739,741|743,750|752,753|758,762 HHHHHHHHH---TT??S?GGG-S???GGGEEEEEGGGGGGG-G?S?-HHHHHGG---GG??TTTGGG-S?TT?TT?S?HHHHHHHHHHH-HHHHHHHHHHHHHHHHHS--S??EEE???TT?EEEEEE?-?TT-?--TTT??EEEEEEE-------------------------EETTTTEEEEEEEETTT-T---------------EEEEEEEEEEEEE?TT??EEEE-------EE??EE---EEET-----------------------------------------------------------------------------------------T----------EEEEE??--??EEEE?TTTT??EEEE?SEEEEEET------------TS?EEEEEEE?-S-----ST---T?SSS--SE---------EEEE--EES--STTG--------GG?GGG?SE--EEEEETT-SEEEEEETT-------------------------------------------------------------------------------?GGG?EEEEETTTS??--???B??----------?G---------G----------G??TTBHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHHHHHHHHH--------------HHHT?--???-?SSEEEEE?SSS??TTS------B???TT?HHHHHHHHHTB??SS?BTT?BTTSGGGG?TT?-??EEEEE 1ZHW|A PF01238.16_PMI_typeI_seed 8 455 !Q:6,6|9,10|29,32|35,35|37,39|45,45|51,53|57,57|67,70|79,79|85,85|90,93|97,100|104,104|116,118|122,124|131,140|145,145|149,150|153,156|164,164|172,173|184,184|192,192|203,205|207,208|217,217|233,233|251,251|253,256|263,269|286,286|302,302|305,305|310,320|323,324|339,342|348,348|351,353|361,367|369,371|376,381|383,384|391,397|404,406|411,411|418,419|423,426|431,434|437,437|454,454 Q:0,5|7,8|11,28|33,34|36,36|40,44|46,50|54,56|58,66|71,78|80,84|86,89|94,96|101,103|105,115|119,121|125,130|141,144|146,148|151,152|157,163|165,171|174,183|185,191|193,202|206,206|209,216|218,232|234,250|252,252|257,262|270,285|287,301|303,304|306,309|321,322|325,338|343,347|349,350|354,360|368,368|372,375|382,382|385,390|398,403|407,410|412,417|420,422|427,430|435,436|438,453 EEEEEE?EE??TTBEEGGGSHHHHHHHHH---?TT-S???TTSEE?EEEES-??TTS?EEETTTTTE----EHHHHHHH?HHHHT?HHHH----HHH--??SSS?SEEEEEEEESS???EEE???HHHHHH----------HHHH?TTT??SS????EEEEESS?EEEEEEE??HHHHHHHHHH?HHHHHHH?HHHHHHHHHH???S??TTSHHHHH-HHHHHHHHHHHHHTS?HHHHHHHHHHHHHHHHH?H----HHHHTT?------TTHHHHHHHHHHHSTT?THHHHTTTTEEEEEE?TT?EEEE?----------TT??EEEEEEEEEEEEES????EEEES?SS???HHHHHHH???????G---GGGB??---?B??TTEEES?------SEEEEE??-SSSS?EEEEEE??TTT--??EEEE???-SS?EEEEEEESEEEEEETT? 1PMI|A PF01239.17_PPTA_seed 143 32 !Q:12,12|15,16 Q:0,11|13,14|17,31 THHHHHHHHHHH?TT?-HHHHHHHHHHHHHHT 4GTR|A PF01241.13_PSI_PSAK_seed 9 98 !Q:0,5|22,22|29,29|31,33|37,37|43,44|46,48|51,55|58,60|81,81|83,83|86,87|90,90|94,97 Q:6,21|23,28|30,30|34,36|38,42|45,45|49,50|56,57|61,80|82,82|84,85|88,89|91,93 ??????HHHHHHHHHHHTTTTT?SSSSSS?S---TTS?SSSSS??S???SS?????SS???TTSSGGGSTTHHHHTTTSSS?S?SS??SS?SSS???? 2WSE|G PF01242.14_PTPS_seed 149 219 !Q:5,5|13,17|21,21|25,29|39,40|43,43|58,66|70,74|77,77|92,92|94,95|102,102|104,105|108,108|115,163|180,189|192,192|196,196|201,202|204,204|212,213|215,218 Q:0,4|6,12|18,20|22,24|30,38|41,42|44,57|67,69|75,76|78,91|93,93|96,101|103,103|106,107|109,114|164,179|190,191|193,195|197,200|203,203|205,211|214,214 EEEEE-EEEEEEE???-?SSS?HHH-----HHHHHGGGG?-TT?EEEEEEEEEEEEEE-?------?TTT?---?SS?HHHHHHHHHHHTHH-H--HTTEEH-H--HH?GGGGSS?--------------------------------------------?--?HHHHHHHHHHHHHTTS---------?TT?EEE-EEEE--E-ETTEEEE--E?-?? 1B66|A PF01243.15_Pyridox_oxidase_seed 141 155 !Q:8,11|16,17|22,22|24,29|31,31|33,33|42,45|47,49|52,53|55,55|63,68|72,81|93,98|108,108|110,110|120,128|130,131|133,133|138,140|142,143|150,151 Q:0,7|12,15|18,21|23,23|30,30|32,32|34,41|46,46|50,51|54,54|56,62|69,71|82,92|99,107|109,109|111,119|129,129|132,132|134,137|141,141|144,149|152,154 SSHHHHHH----HHHH--HHHH?T------T?S?TTEEEEEE----E?--TT--S?EEEEEEE--??-?EET----------TEEEEEEETTS------HHHHHHHHS?E-EEEEEEEGG---------G--T-EEEE---E--EEEEEE??HHH 3A6Q|A PF01244.16_Peptidase_M19_seed 48 497 !Q:6,7|13,15|24,24|27,40|42,43|47,48|57,58|66,92|117,117|124,124|136,136|139,139|148,148|153,154|157,157|159,161|172,173|177,178|180,180|183,184|188,188|192,193|198,199|207,207|222,222|226,226|230,230|239,245|248,248|251,251|258,258|264,265|268,269|272,272|284,284|290,291|295,295|298,300|316,320|328,330|337,337|356,358|375,376|384,385|387,390|394,435|440,440|442,460|474,474|477,478|497,497 Q:0,5|8,12|16,23|25,26|41,41|44,46|49,56|59,65|93,116|118,123|125,135|137,138|140,147|149,152|155,156|158,158|162,171|174,176|179,179|181,182|185,187|189,191|194,197|200,206|208,221|223,225|227,229|231,238|246,247|249,250|252,257|259,263|266,267|270,271|273,283|285,289|292,294|296,297|301,315|321,327|331,336|338,355|359,374|377,383|386,386|391,393|436,439|441,441|461,473|475,476|479,496 HHHTTS??EEEEE???TTTTBTTB?TT--------------S??SSS??HHHHHHHT??EEEEEEE??????????-----------??????TTHHHHHHHHHHHHHHHHHHHHHH?TTTEEE?SSHHHHHHHHH-TT?EEEEEEEE?SGGG--TT?T---HHHHHHHHTT??EEE??S-SS??SSB?BSS??GGGT??TTTTSSB?HHHHHHHHHHHHHT?EEE?TTB?HHHHHHHH-------HH?SS?EEEEEE?BTTTS??TT--SB?HHHHHHHHHTT?EEEEE??HHH-HS???HHHHHHHHHHHHHTT?????SSTTTSS???GGGGGS?HHHHHHHHHHHHHHHHTS???BHHHHHHHHHHHHHHH?-GGGEEEE??B----TTT??----------------------------------------BBTB?S-------------------GGGHHHHHHHHHH-HT??HHHHHHHTTHHHHHHHHH- 3LU2|A PF01245.15_Ribosomal_L19_seed 127 192 !Q:0,3|6,8|15,24|26,29|31,37|39,61|63,87|91,92|94,94|96,96|99,100|102,107|109,111|116,119|121,123|129,134|136,137|141,162|165,165|167,167|170,177|182,188|190,191 Q:4,5|9,14|25,25|30,30|38,38|62,62|88,90|93,93|95,95|97,98|101,101|108,108|112,115|120,120|124,128|135,135|138,140|163,164|166,166|168,169|178,181|189,189 ??-?HH---HHTTTS?-----?--?S--??S???????S??????---------?------?S-------------------------TTS??S?S?SS??S??-?--S?--TTTT????S-??STTSS??????S??SSS?????--??------------?SS?S?SS????----SSSS??-?-??S?? 2ZJQ|M PF01246.15_Ribosomal_L24e_seed 7 71 !Q:0,3|5,5|9,10|12,13|16,17|22,22|26,26|43,44|48,48|51,51|55,70 Q:4,4|6,8|11,11|14,15|18,21|23,25|27,42|45,47|49,50|52,54 ????B?TTT??B??TT??EEEE?TTS?EEEESSHHHHHHHHTT??TTT?TT?STT???????????????? 1S1I|S PF01247.13_Ribosomal_L35Ae_seed 44 114 !Q:0,0|2,4|14,14|17,17|30,32|42,42|50,51|53,55|59,67|73,73|86,89|97,97|99,101|106,106|108,110|113,113 Q:1,1|5,13|15,16|18,29|33,41|43,49|52,52|56,58|68,72|74,85|90,96|98,98|102,105|107,107|111,112 ?S--?BEEEEEEEE?SS?EEEEEEEEEESS???HHHHGGGTT?EEEEEEE??S???STT----???-?SEEEE-EEEEEEEETTTT----EEEEEES-S???STTT-T???EE? 3J39|f PF01248.21_Ribosomal_L7Ae_seed 54 111 !Q:15,15|31,34|42,43|51,56|64,65|69,70|72,73|78,80|90,90|93,95|103,103|106,106 Q:0,14|16,30|35,41|44,50|57,63|66,68|71,71|74,77|81,89|91,92|96,102|104,105|107,110 HHHHHHHHHTTSSSE-EEESHHHHHHHHHHT--??SEEEEES??SSGGGTT------THHHHHT--TTT??E--EEES--?SHHHHTTTT?SS?-?SEEEEEE?TT?HHHH 1S1I|G PF01249.13_Ribosomal_S21e_seed 36 86 !Q:0,0|8,8|11,14|16,16|20,21|23,24|27,27|30,30|39,39|43,45|55,57|59,59|67,67|82,85 Q:1,7|9,10|15,15|17,19|22,22|25,26|28,29|31,38|40,42|46,54|58,58|60,66|68,81 ?EETTTEE?SS????B?TTT??B??TT?TT?EEEEEEEE?SSS??-EEEEEEEEE---E?HHHHHTT?THHHHHHHHHHHSS???? 2XZM|Z PF01250.12_Ribosomal_S6_seed 180 115 !Q:0,9|13,13|16,16|33,33|35,49|51,74|76,89|103,103|106,114 Q:10,12|14,15|17,32|34,34|50,50|75,75|90,102|104,105 ??????????TTS?HH-HHHHHHHHHHHHHHTT-T????-????---?-?S-????-??????----------??S?????-????--?-HHHHHHHHHHHHH?TT????????? 3KIX|f PF01251.13_Ribosomal_S7e_seed 27 203 !Q:5,5|8,14|32,34|43,47|51,51|54,54|57,57|59,59|67,67|75,75|91,91|100,108|111,112|114,116|118,123|127,127|141,141|144,144|153,153|157,157|165,166|172,173|191,191|197,202 Q:0,4|6,7|15,31|35,42|48,50|52,53|55,56|58,58|60,66|68,74|76,90|92,99|109,110|113,113|117,117|124,126|128,140|142,143|145,152|154,156|158,164|167,171|174,190|192,196 HHHHS?SS??---??THHHHHHHHHHHHHSSS---STTTTTTT?????EEE-EE?TT-S?EEEEEEE?SSSHHHH-HHHTHHHHHHHHHHS?SEEEEEEE?????????SS--S??-S??????STT?HHHHHHHHHHHHS?SS?EEEEEEEE?SSS?EEEEEEE??TTTHH--HHTTHHHHHHHHHHHHS?EEEEE?????? 2XZM|3 PF01253.17_SUI1_seed 161 150 !Q:0,4|7,11|16,23|25,25|29,42|46,48|50,55|57,58|61,72|88,90|92,114|117,118|122,122|124,125|129,129|133,136|140,141|145,145|148,149 Q:5,6|12,15|24,24|26,28|43,45|49,49|56,56|59,60|73,87|91,91|115,116|119,121|123,123|126,128|130,132|137,139|142,144|146,147 ?????EE-----EEEE?-----??S-SSS-----------???EEE---E?-??--S-?HH------------HHHHHHHHHTTSSSS?-?B?-------------------?--SS?-EEE?S??HHH-HHH----HHH--HHT?EE?? 2IF1|A PF01255.14_Prenyltransf_seed 94 394 !Q:1,4|13,16|18,20|43,44|46,46|60,60|63,63|66,66|80,80|89,91|93,95|98,98|105,105|107,107|111,112|127,127|129,132|134,136|138,138|147,147|154,163|171,217|225,226|230,282|284,285|288,291|293,295|302,303|307,325|330,330|333,336|347,347|349,350|354,354|357,357|361,362|376,393 Q:0,0|5,12|17,17|21,42|45,45|47,59|61,62|64,65|67,79|81,88|92,92|96,97|99,104|106,106|108,110|113,126|128,128|133,133|137,137|139,146|148,153|164,170|218,224|227,229|283,283|286,287|292,292|296,301|304,306|326,329|331,332|337,346|348,348|351,353|355,356|358,360|363,375 E-???HHHHHHTT----T??-HHHHHHHHHHHHHHHHHHHHHT--T?SEEEEEEEETTGG-GS?HH-HHHHHHHHHHHHH-HHHHHHHH---H---TT?EEEEES?G-GGS-?HHHHHHHHHHHHHH-T----T??-S?EEEEEEEE?HHHHHH----------HHHHHHH-----------------------------------------------HHHHTTS??GGG---------------------------------------------------??H--HH----H---HTTSTT--TTS??------------?---?EEEE?SS????TTSSTTTTTT?E--EEE?SS?GGG??HHHHHHHHHHHHT?-----------?????? 1F75|A PF01256.12_Carb_kinase_seed 9 290 !Q:4,6|10,10|25,27|34,36|47,47|50,50|53,53|59,65|71,77|79,80|86,86|89,90|92,92|98,101|112,115|119,119|123,124|126,140|143,143|147,149|158,160|163,169|193,193|197,197|201,201|203,204|207,207|211,215|219,219|238,238|240,248|273,273|276,276|278,279 Q:0,3|7,9|11,24|28,33|37,46|48,49|51,52|54,58|66,70|78,78|81,85|87,88|91,91|93,97|102,111|116,118|120,122|125,125|141,142|144,146|150,157|161,162|170,192|194,196|198,200|202,202|205,206|208,210|216,218|220,237|239,239|249,272|274,275|277,277|280,289 EEEE???SSS?HHHHHHHHHHHTTT--?SEEEEE?-?TTTHHHHTTT?TT?EE?TTHHH-------HTTTS----???S??SEEEE?TT??S?HHHHH----HHHHHTTSSS?---EEE?GGG??S???---------???SS?EEE???HHHHHHHH???HH-------HHTTSHHHHHHHHHHHHTSEEEE?STT?EEE?T--TS?EEE?????GGG?STTHHHHHHHHHHHHHHH?S---------SHHHHHHHHHHHHHHHHHHHHHHS?TT-S??HHHHHHHHHH 3RTB|A PF01257.14_2Fe-2S_thioredx_seed 178 199 !Q:8,8|10,11|13,14|29,35|37,38|40,40|42,43|56,57|59,59|70,71|74,80|83,85|87,87|94,94|102,103|118,121|123,123|125,135|139,139|147,148|150,150|152,152|155,155|157,157|160,164|167,176|178,180|182,186 Q:0,7|9,9|12,12|15,28|36,36|39,39|41,41|44,55|58,58|60,69|72,73|81,82|86,86|88,93|95,101|104,117|122,122|124,124|136,138|140,146|149,149|151,151|153,154|156,156|158,159|165,166|177,177|181,181|187,198 HHHHHTTS?T--T??GGGHHHHHHHHHHH-------H--S-S??HHHHHHHHHHHT--S?HHHHHHHHTT?-SS??-----SS???S-EEEEEE?SHHHHTT--THHHHHHHHHHHHT?--?T-T----???----TTS?EEEEEES??S?G-GG?S?EE?----SS----------S-??B???-?HHHHHHHHHHHH 3I9V|2 PF01258.12_zf-dskA_traR_seed 241 47 !Q:1,2|5,7|9,10|13,14|16,17|21,21|26,27|29,29|31,32|34,34|38,40|47,47 Q:0,0|3,4|8,8|11,12|15,15|18,20|22,25|28,28|30,30|33,33|35,37|41,46 S??SB--?T--TT??B??HHH-HHHS--T-T??S?HHH---HHHHHH- 2KQ9|A PF01259.13_SAICAR_synt_seed 11 307 !Q:2,2|7,12|23,24|32,32|34,35|42,42|45,46|68,68|74,77|80,81|87,87|102,102|109,110|113,113|123,124|126,129|142,143|148,149|152,153|156,156|164,165|167,176|178,187|196,196|246,247|249,249|261,266|270,273|288,288|291,292|294,298|300,303 Q:0,1|3,6|13,22|25,31|33,33|36,41|43,44|47,67|69,73|78,79|82,86|88,101|103,108|111,112|114,122|125,125|130,141|144,147|150,151|154,155|157,163|166,166|177,177|188,195|197,245|248,248|250,260|267,269|274,287|289,290|293,293|299,299|304,306 SS?EEEE-----?SSEEEEEEET--TEEEEEE?S??EETTEE?SS??TTHHHHHHHHHHHHHHHTTTT-SEESB????TT??GGGGS?GGGGSHHHHHHHTT-SEEEEE??EE?SSBEEEEEE??H----HHHHHHHHHSEE--TTEE??TT??TT?EEEEEEE??B??????????B??--------HHHHHHHH?HHHHHHHHHHHHHHHHHHHHHHHHHTEEEEEEEEEEEEETTTTEEEEES??S?TTTEEEEETTT??----TTS????SSTHHHHHHHHHTT?TT?-T-----T????HHH 4JA0|A PF01261.19_AP_endonuc_2_seed 311 470 !Q:4,6|11,13|18,19|22,22|25,25|28,48|64,99|104,123|125,126|129,130|133,133|139,139|155,157|161,174|176,179|181,187|191,252|254,254|259,259|262,265|274,275|284,288|291,295|297,297|302,306|310,311|314,333|344,344|346,346|349,350|366,379|397,407|417,419|424,452|455,459|462,462|467,467 Q:0,3|7,10|14,17|20,21|23,24|26,27|49,63|100,103|124,124|127,128|131,132|134,138|140,154|158,160|175,175|180,180|188,190|253,253|255,258|260,261|266,273|276,283|289,290|296,296|298,301|307,309|312,313|334,343|345,345|347,348|351,365|380,396|408,416|420,423|453,454|460,461|463,466|468,469 HHHH---HHTT--?SEEE??SS?SS?SS???-------?---------?HHHHHHHHHHHHHTT??----------------------------------GGGB??------------------B??TT??TT?SSHHH-HHHHHHHHHHHHHHH---HHT--------------T--??E-------EEE???-----------------------------------------------------------B?TTTS?HH----HHHHHHHH--HHHHHHHH----?SS----?E-EEEE?????TTB??SS--------------------HHHHHHHHHH?S?GG--GEEEEEEHHHHHHHT??-----------?SSHHHHHHHHHHHHHHT?----------GGGEEEEEE--?EESS----------------------------?TT?????EE?TTTS-SS 3QXB|A PF01262.16_AlaDh_PNT_C_seed 96 227 !Q:7,10|13,13|18,23|29,30|46,46|54,54|72,105|108,109|120,120|126,137|139,139|147,166|169,169|174,217|226,226 Q:0,6|11,12|14,17|24,28|31,45|47,53|55,71|106,107|110,119|121,125|138,138|140,146|167,168|170,173|218,225 TSGGGTS????TT?BTBB??---?EEEEE??SHHHHHHHHHHHHTT?EEEEEES?HHHHHHHHHHTTTSEEE----------------------------------EE??HHHHHHHHHH?SEEEE????????????S?HHHHTTS?-------------------TT?EEEE??????-------??????????---------------??????EETTEEEE? 2VHW|A PF01263.15_Aldose_epim_seed 66 402 !Q:6,6|8,9|11,11|29,29|33,33|37,37|39,41|44,46|54,54|56,60|63,63|66,66|69,69|73,73|87,89|92,107|118,118|124,124|131,139|149,150|154,154|157,161|163,163|175,175|178,180|191,195|197,197|200,200|202,202|205,207|209,209|212,212|215,218|220,221|224,224|229,229|231,232|236,237|239,239|241,241|244,244|246,246|248,249|252,252|258,263|266,266|278,287|294,303|306,306|334,335|338,338|341,346|350,350|353,353|355,356|363,363|371,371|377,377|381,386|389,389|393,393 Q:0,5|7,7|10,10|12,28|30,32|34,36|38,38|42,43|47,53|55,55|61,62|64,65|67,68|70,72|74,86|90,91|108,117|119,123|125,130|140,148|151,153|155,156|162,162|164,174|176,177|181,190|196,196|198,199|201,201|203,204|208,208|210,211|213,214|219,219|222,223|225,228|230,230|233,235|238,238|240,240|242,243|245,245|247,247|250,251|253,257|264,265|267,277|288,293|304,305|307,333|336,337|339,340|347,349|351,352|354,354|357,362|364,370|372,376|378,380|387,388|390,392|394,401 EEEEEE?S--S?EEEEETBTTEEEEEEEE?TTS?EEE?B???SS---HHHHHSS?S----?TT?EE?SB?SEE-GGGEEEETTEEEE???TB----------------TTBEETTSSS?GGGSB?EEEEET---------TEEEEEEEE-?TTG-GG---??S?EEEEEEEEEET-TE---EEEEEEEEES-----S?EE?B?EE???B?TT?TT?---S??TT?EEEE?E--EEE??B?T-TS?B?S??EE?TTSTT-??---SS?EEHHHHHHHTT------????EEEEEE??-------?SS?EEEEEEEETTTTEEEEEEESSSEEEEE??TT?EE------EEE?GG-G-?EEETTS?BEEEEES?TTGGG?TTS?---??EE?TTS?EEEEEEEE 3K25|A PF01264.16_Chorismate_synt_seed 158 469 !Q:0,0|6,7|19,21|24,24|26,27|40,41|44,57|59,60|69,69|72,77|80,80|83,83|90,94|96,144|149,149|151,153|184,186|190,195|207,213|216,216|227,227|237,238|240,244|248,253|256,257|259,260|262,262|276,276|282,283|285,285|295,302|305,305|307,307|314,314|336,337|351,353|355,360|366,366|368,377|381,381|384,389|400,400|403,403|411,446 Q:1,5|8,18|22,23|25,25|28,39|42,43|58,58|61,68|70,71|78,79|81,82|84,89|95,95|145,148|150,150|154,183|187,189|196,206|214,215|217,226|228,236|239,239|245,247|254,255|258,258|261,261|263,275|277,281|284,284|286,294|303,304|306,306|308,313|315,335|338,350|354,354|361,365|367,367|378,380|382,383|390,399|401,402|404,410|447,468 ?EEEEE??TTSSEEEEEEE???BT?B??HHHHHHHHHHHH--TT?---??-???????S??EEEEESEE-TT------EE?SS?EEEEEE?----S????????????---------------??????????????????????TTTT-T--?SSTHHHHHHHSGGGHHHHHHHHHHHHHHHH---TTT-----?EEEEEEEEETT-------EE?GGGSSGGGGG?HHHHHHHHH--H-----HTT------ST--T??S?GGGHHHHHHHHHH-HHTTT??B?EEEEEEEES------??TT?S?SSSGGG?HHHHHHHHHHTSTTEEEEEET--TGGGGGGSBGGGT???E------EEETT-T----------EEE-ES----??TTTTEETTEE?SS?EEEEEEE????????-??????????????????---??????HHHHHHHHHHHHHHHHHHHHHH 2O12|A PF01266.19_DAO_seed 530 1715 !Q:5,7|21,29|32,36|41,41|44,44|48,82|86,88|90,90|92,158|161,161|165,165|168,168|171,171|178,181|185,278|280,284|289,307|309,314|316,320|322,327|333,341|346,347|350,351|354,366|372,373|378,378|381,389|391,395|398,398|401,401|408,434|437,443|445,453|455,464|466,480|482,489|492,492|496,498|501,503|513,515|517,536|538,539|541,541|543,544|546,546|548,553|555,557|559,564|567,570|572,578|580,591|595,600|603,604|609,653|659,689|691,695|697,697|700,707|709,709|712,725|731,740|743,746|749,752|755,755|757,757|762,762|764,765|767,820|826,826|828,829|831,832|836,861|864,865|868,886|888,888|890,895|898,952|961,999|1003,1076|1079,1080|1082,1104|1108,1120|1122,1123|1127,1240|1242,1245|1247,1256|1262,1332|1334,1335|1340,1346|1349,1352|1356,1400|1406,1406|1410,1415|1417,1417|1420,1508|1511,1514|1517,1590|1594,1655|1661,1661|1666,1666|1672,1673|1675,1676|1679,1694|1699,1702|1709,1709 Q:0,4|8,20|30,31|37,40|42,43|45,47|83,85|89,89|91,91|159,160|162,164|166,167|169,170|172,177|182,184|279,279|285,288|308,308|315,315|321,321|328,332|342,345|348,349|352,353|367,371|374,377|379,380|390,390|396,397|399,400|402,407|435,436|444,444|454,454|465,465|481,481|490,491|493,495|499,500|504,512|516,516|537,537|540,540|542,542|545,545|547,547|554,554|558,558|565,566|571,571|579,579|592,594|601,602|605,608|654,658|690,690|696,696|698,699|708,708|710,711|726,730|741,742|747,748|753,754|756,756|758,761|763,763|766,766|821,825|827,827|830,830|833,835|862,863|866,867|887,887|889,889|896,897|953,960|1000,1002|1077,1078|1081,1081|1105,1107|1121,1121|1124,1126|1241,1241|1246,1246|1257,1261|1333,1333|1336,1339|1347,1348|1353,1355|1401,1405|1407,1409|1416,1416|1418,1419|1509,1510|1515,1516|1591,1593|1656,1660|1662,1665|1667,1671|1674,1674|1677,1678|1695,1698|1703,1708|1710,1714 SEEEE?-?SHHHHHHHHHHHH---------TT?---?EEEE?SS-STT?----------------------------------SHH---H-H?--???--????------------------------------------------------------?SS-HHH-HH-HH-HHHHHH----HHH----------------------------------------------------------------------------------------------H-----HHHH-------------------T??----E-----E---???EEEEE-?-------SHHH--HH--HH-------------HHHHH--HHHH-TT?------??E-----EE?HH-HHHHSS---------------------------TT??----?T---------T?--------?E---------------E--------EE-ETT??-EE--?HHHHHHHHH---H--------------------H--H-H--H-T------T--?E------EE---?S??-----E------------EEE------EE--SSSB---------------------------------------------EEEEE-------------------------------E-----T-TE--------E-EE?-------------SEEEE??--------GG----GH----HH-H-HHHH-T??S?--------------------------------------??-?-----------EEEEE-E--E--EEE?-------?----------------?ST--TS-------------------S?S------EE-------------------------------------------------------EESTTTTE---------------------------------------EEE?-----------------------------------------------------------------------?-SS--S?-------?--------------EEE------------?S??BSS--------------------------------------------?--???-----------------------------------------------------------?--??H----H----------HHHHH-----------------------------------------------------------------------H--HHHH-------HH?---GGG---------------------------------------------GGSEE-EEE------E-EE-----------------------------------------------------------------------------------------EE----EE--?-----------------------------------------------------------------------TTS?------------------------------------------------------------?EEEEE-SSSB-TEEEE--E??TT?---------------HHHH----HHHHHH-HHHHH 2E4A|A PF01267.12_F-actin_cap_A_seed 39 492 !Q:5,6|14,15|18,18|30,30|32,43|45,45|52,54|68,68|71,72|75,75|78,78|81,82|84,84|89,98|127,139|145,149|151,152|161,164|171,172|175,175|180,316|326,347|376,380|384,384|398,398|414,419|423,425|428,428|463,463|468,468|471,471|474,474|476,478|482,482|485,491 Q:0,4|7,13|16,17|19,29|31,31|44,44|46,51|55,67|69,70|73,74|76,77|79,80|83,83|85,88|99,126|140,144|150,150|153,160|165,170|173,174|176,179|317,325|348,375|381,383|385,397|399,413|420,422|426,427|429,462|464,467|469,470|472,473|475,475|479,481|483,484 HHHHH--HHHHHHT??TT?HHHHHHHHHHH-H??----------H-HHHHHH---HHHHHHHHHHHTT?EE??TT?SS?EE??G-GGEE----------ETTEEEETTTTEEEEEETTTTEEEEEEE--------?????SSHHH-----H--HHHHHHHH----HHHHHH?-SS?EEEE-----------------------------------------------------------------------------------------------------------------------------------------EEEEETTEE----------------------EEEEEEEEEEEEGGGTEEEEEEEEEEEE?---?TTE-EEEEEEEEEEEEE?TTEEEEEEEEEEEEE------EEE-??SH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT-TTTS?SS?TT?S???HHH-HT??????? 3LK2|A PF01268.14_FTHFS_seed 141 721 !Q:0,2|11,16|23,23|26,26|28,29|33,34|42,42|46,46|49,49|53,54|57,59|63,78|87,89|92,94|107,107|111,116|118,119|125,128|136,139|149,149|183,184|186,239|241,241|243,243|247,250|256,257|267,270|275,276|278,280|284,284|300,300|303,308|319,319|325,328|332,332|341,341|355,355|363,364|369,373|378,379|381,382|393,393|395,409|418,418|436,439|447,447|456,459|461,463|467,482|485,486|495,495|508,508|511,512|519,520|523,524|536,537|539,539|542,542|544,544|546,546|551,551|556,557|573,573|575,578|581,597|600,600|604,605|619,620|626,626|641,642|646,646|648,649|651,652|655,655|662,663|666,667|669,669|674,674|689,689|691,693|696,699|702,702|707,707|710,711|714,715|719,720 Q:3,10|17,22|24,25|27,27|30,32|35,41|43,45|47,48|50,52|55,56|60,62|79,86|90,91|95,106|108,110|117,117|120,124|129,135|140,148|150,182|185,185|240,240|242,242|244,246|251,255|258,266|271,274|277,277|281,283|285,299|301,302|309,318|320,324|329,331|333,340|342,354|356,362|365,368|374,377|380,380|383,392|394,394|410,417|419,435|440,446|448,455|460,460|464,466|483,484|487,494|496,507|509,510|513,518|521,522|525,535|538,538|540,541|543,543|545,545|547,550|552,555|558,572|574,574|579,580|598,599|601,603|606,618|621,625|627,640|643,645|647,647|650,650|653,654|656,661|664,665|668,668|670,673|675,688|690,690|694,695|700,701|703,706|708,709|712,713|716,718 ???HHHHHHHS?--???HHHHHH-HT-T??GGG--EEEBSSS?EEE?HH-HHH--HT---TTS?-------------??EEEEEEES???TT???HHHHHHHHHHHH-HHT------T??EEEEE????SGGGGSS????SEETTEEEE?HHHHHTTTTSHHHHHHHHHHHHHHHHHHHHHTT?-T------------------------------------------------------T?B?GGG????EEESS??GGGSSEEES?---SSGG--G???EEE?EEEGGGSHHHHHHHH?SS------HHHHHHHHHT?EEEEB----TTS?EEETTTTT?HHHHHHHTTTTTS?EEEEETT??EEEE?????SSSS??B??HHHHHHHHHH?S---------------EEEEEBSS?TTTHHHHHHHTHHHHHT-???SEEEEEE?HHHHHHTT----T?-?GGG---------------?SS??HHHHHHHH-HHHHHHHHHHHT-TT??EEEEEE??TT??HHHHHHHHHHH--H-HT-T?E-EEEE?HHHH--GGGGGHHHHHHHHHH-H----HH???-?---------???SS?TTS-?HHHHHHHHHHHTT??SEEEE?HHHHHHHHHHHHTT-?TTS?B??B??SS?SSSSTT??SS??S?EEEE?EEEEETTTTEEEEE?S???SS????SS?TTTS?EE?-TT??EES?? 1FPM|A PF01269.12_Fibrillarin_seed 42 246 !Q:0,0|3,4|12,22|26,26|31,32|36,37|42,54|60,61|65,65|75,75|77,81|84,84|90,91|105,105|108,108|114,116|125,126|132,132|139,139|141,141|144,144|152,155|162,165|196,196|200,200|215,217|227,227|229,229|244,246 Q:1,2|5,11|23,25|27,30|33,35|38,41|55,59|62,64|66,74|76,76|82,83|85,89|92,104|106,107|109,113|117,124|127,131|133,138|140,140|142,143|145,151|156,161|166,195|197,199|201,214|218,226|228,228|230,243 ?EE?-SSTTEEE??-?????--?EEE?SSTT??SSS??EEEE???-------???EEEEE??TTT?HHHHHHHTT?S?????TT?EEEEE??TTSHHHHHHHHHH?TT?EEEEE???HHHHHHHH--HHHHH?TTEEEE?S?TT?GGGGGGG??-?EEEEEE????TTHHHHHHHHHHHHEEEEEEEEEEEEHHHH?SSS?HHHHHHHHHHTTGG---GTEEEEEEE-E?TTTSSSEEEEEEEE??- 3DH0|A PF01270.12_Glyco_hydro_8_seed 7 402 !Q:1,1|3,9|12,16|19,19|41,43|49,50|53,59|64,66|105,105|107,108|110,110|115,115|119,119|129,134|153,153|159,159|178,179|182,183|185,185|187,187|192,193|195,195|198,200|202,202|206,207|213,213|220,221|243,243|247,250|258,259|263,264|271,271|278,278|296,297|318,318|322,323|325,325|327,327|331,331|333,335|337,338|343,344|354,354|364,368|376,385 Q:0,0|2,2|10,11|17,18|20,40|44,48|51,52|60,63|67,104|106,106|109,109|111,114|116,118|120,128|135,152|154,158|160,177|180,181|184,184|186,186|188,191|194,194|196,197|201,201|203,205|208,212|214,219|222,242|244,246|251,257|260,262|265,270|272,277|279,295|298,317|319,321|324,324|326,326|328,330|332,332|336,336|339,342|345,353|355,363|369,375|386,401 S?S??????-TT?????SS?HHHHHHHHHHHHHHHHHHHEE???TTSTT??EE???????BTTB???EEHHHHHHHHHHHHHTBTTBTTHHHHHHHHHHHHHHTB?S--S?TTSB?SEE?SSGGGTTTS---???HHHHHHHHHHHHHHHHHH?SSSSS?HHHHHHHHHHHTHHHHHB?-TT--S?B?SSTT--S?TT???B?GGG??HHHHH-HHHHHH??THHHHHHHHHHHHHHHHHHHH?TTT????SSEETTT--TEE??TTGGGS?TTTTSB?TTGGGHHHHHHHHHHHH??HHHHHHHHHHHHHHHHHTTT?GGG??S?B?TTS?B???S??HHHH--HHHHHTTTT?GGGHHHHHH-----HHHHHTT??------??HHHHHHHHHHHHHHTT 1IS9|A PF01272.14_GreA_GreB_seed 137 104 !Q:1,7|10,11|14,14|19,20|23,24|37,37|39,48|51,51|54,56|60,61|76,76|78,78|81,81|84,95|103,103 Q:0,0|8,9|12,13|15,18|21,22|25,36|38,38|49,50|52,53|57,59|62,75|77,77|79,80|82,83|96,102 S??----?SB??TT?EEEE--EE--TTTTEEEEEEEE?T----------TT?BG---GGT--EEESSSHHHHHHTT?B-TT?EE???????-???-EEEEEEE? 3AOH|X PF01273.20_LBP_BPI_CETP_seed 36 228 !Q:19,23|35,54|70,73|85,85|91,96|105,106|112,117|119,119|128,129|163,166|172,172|176,179|181,181|204,207|216,216|221,223 Q:0,18|24,34|55,69|74,84|86,90|97,104|107,111|118,118|120,127|130,162|167,171|173,175|180,180|182,203|208,215|217,220|224,227 HHHHHHHHHHHHHHHHHTT?????EEEEEEETTTE--------------------EEEEEEEEEEEEEEE???-EEEEEETTTEE-EEEEE------EEEEEEEE--EEEEE------E-TTEEEEEE--EEEEEEEEEEEEEEEEEEETTTTEEEEEEEEEE????EEEEE?TTS----S?HHHHHHHHHHTHHHHHHHHHHH----HHHHHHHH-HHHH---HHHH 2OBD|A PF01274.17_Malate_synthase_seed 16 744 !Q:12,14|26,26|55,61|76,87|89,90|96,99|107,107|133,145|165,170|174,176|178,185|187,197|205,215|228,244|250,251|262,265|284,286|299,303|308,308|312,312|317,317|320,320|326,328|331,331|338,338|340,340|344,344|353,355|371,372|377,377|379,380|382,382|386,386|392,392|394,395|416,417|420,420|428,428|453,453|469,471|473,477|484,484|486,489|502,507|513,513|522,525|529,529|545,545|567,568|579,590|596,600|602,603|606,608|634,637|642,642|645,646|651,651|672,672|676,679|692,692|698,708|710,710|713,727|729,729|733,733 Q:0,11|15,25|27,54|62,75|88,88|91,95|100,106|108,132|146,164|171,173|177,177|186,186|198,204|216,227|245,249|252,261|266,283|287,298|304,307|309,311|313,316|318,319|321,325|329,330|332,337|339,339|341,343|345,352|356,370|373,376|378,378|381,381|383,385|387,391|393,393|396,415|418,419|421,427|429,452|454,468|472,472|478,483|485,485|490,501|508,512|514,521|526,528|530,544|546,566|569,578|591,595|601,601|604,605|609,633|638,641|643,644|647,650|652,671|673,675|680,691|693,697|709,709|711,712|728,728|730,732|734,743 HHHHHHHTSTTS???HHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHH???????HHHHHHHHHHTTSS????????????S??HHHHT????EEEEETT?HHHHHHHHHTTEEEHHHHHHTSTTS?????????????HHHHHHHHHHHHHHHHHHS??????GGG???B????????B???????????GGGEEEB???????????EEEETTEEEEEE???????????-?????EEEEE??SEEEEESSTT????SHHHHHHHHHHHHHHHHT???EEEEETTEEEEE?????EEEE?TTS?EEEE?SS?EEEEE???SS?EEEEEE-E?STT?SSEEEEHH---HHHHHHHHHHHGGGT??SGGG?S??S?SSS?EEEEE?S??SHHHHHHHHHHHHHHHHHHT??TT?EEEEEEE?SHHHHTTHHHHHHHTTTTEEEEEE?HHHHHHHHHHHTGGG-??B?---?TTTGGG?H----HHHHHHHHHHHH------HHHTT?TTTSEEEE????BSS?HHHHHHHTTHHHHTT?SEEEESSHHHHHHHHHHHHHS?-HHHHHHHHTT??---???----HHHHT?--??B??TT???HHHHHHHHHHHHHHHHHHHHHHHHH????EEEE?TT??EEEE?HHHHHHHHHHHHHHHHTTSS?HHH----HHHHHHHHHHHH-HHHTT-----------T?TT????----------?S?GGG?HHHHHHHHHH 2JQX|A PF01276.15_OKR_DC_1_seed 10 461 !Q:0,0|13,14|17,17|42,42|49,51|54,54|58,58|80,80|102,103|106,106|114,115|127,128|134,134|136,139|142,146|148,148|152,153|171,171|173,174|184,184|191,191|210,210|213,213|220,220|227,227|231,235|239,239|253,254|257,257|264,264|273,275|288,288|291,292|330,337|342,342|349,349|357,362|367,367|374,374|379,381|384,384|388,390|392,393|400,400|408,408|412,412|416,416|419,419|422,424|436,436|440,440|444,444|452,453|456,457 Q:1,12|15,16|18,41|43,48|52,53|55,57|59,79|81,101|104,105|107,113|116,126|129,133|135,135|140,141|147,147|149,151|154,170|172,172|175,183|185,190|192,209|211,212|214,219|221,226|228,230|236,238|240,252|255,256|258,263|265,272|276,287|289,290|293,329|338,341|343,348|350,356|363,366|368,373|375,378|382,383|385,387|391,391|394,399|401,407|409,411|413,415|417,418|420,421|425,435|437,439|441,443|445,451|454,455|458,460 ?HHHHHHHHHHTT??EE?SSSTTTTTTTGGGSHHHHHHHHHH?HHHHHT???TT?GGG?BTTTTBTHHHHHHHHHHHHHT?SEEEEESSHHHHHHHHHHTTS??TT?EEEEETT??HHHHHHHTTTT??EEEEE?B?-??TT?????B?GGG??HHHHHHHTGGGHHHHTT?S??EEEEEEESB?TTSEEE?HHHHHHHHGGGEEEEEEE?TT?SGGGSS-STTGGG?STT?????TTS?EEEEEEEHHHHSS??TT?EEEEEE?GGGSSSSS???HHHHHHHHHHHS?SS??SHHHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHHHHH--------HHHT?SSEESS?SEETTEE------GGGS?HHHHTT?GGGS???TT?TTT???S??TTSEEE?TTEEEEE?TTB?TTT?SB?SS???HHHHHHHHHHT-TEE?SEE?SSEEEEE??TT??HHH 2VYC|A PF01278.15_Omptin_seed 7 304 !Q:0,0|3,9|12,12|60,61|77,77|87,89|91,94|100,100|128,128|150,151|156,157|160,160|163,163|165,166|168,169|172,172|219,219|223,223|274,274|303,303 Q:1,2|10,11|13,59|62,76|78,86|90,90|95,99|101,127|129,149|152,155|158,159|161,162|164,164|167,167|170,171|173,218|220,222|224,273|275,302 ?TT--?????TT?EEEEEEEEEEEEEEEEEEEETTTTTEEEEEEEEEEEEEEEEEEEEEE??SSSEEEEEEEEEESS?EEEEEEEEE???T----TSTTS?SEEEEEEEEEEEEEEEEEEEEEEEEEE?SSEEEEEEEEEEEEEEEEEEE??EEEB??TT?SS?B??B??TT?SEEEEEEEEEEEEEEEEEEEEETTEEEEEEEEEEEEEEEEEEEEEE?SSS?EEEEEEEEEEEEEEEEEEEEEEEETTEEEEEEEEEEEEEEEEEEEEEEET-TTTEEEEEEEEEEEEEEEEEEEEEEEEE? 2X56|A PF01279.12_Parathyroid_seed 11 137 !Q:0,16|32,136 Q:17,31 ---??????????????HHHHHHHHHHHHHHH????????---------------------------------????????????????????????-?????--??????????????----?????????????? 1HPY|A PF01280.15_Ribosomal_L19e_seed 63 183 !Q:0,1|15,20|22,22|26,26|29,31|34,34|41,42|58,86|98,98|103,103|108,109|111,111|116,116|118,118|143,143|145,145|152,154|165,165|176,176 Q:2,14|21,21|23,25|27,28|32,33|35,40|43,57|87,97|99,102|104,107|110,110|112,115|117,117|119,142|144,144|146,151|155,164|166,175|177,182 ??THHHHHHHHHHHT------S?GGG?EE--?TT?HHHHHH??SSHHHHHHHHTTSEE????--------------------?????HHHHHHHHHHH-TTSS?SGGG??S?HHHH-S?HHHHHHHHHHHHHHHHHHHHHHTS-S?HHHHHH---HHHTTSSSSS?SHHHHHHHHH-HHHHHH 1S1I|P PF01281.14_Ribosomal_L9_N_seed 157 55 !Q:0,0|7,8|12,12|16,16|20,21|38,39|43,45|50,53 Q:1,6|9,11|13,15|17,19|22,37|40,42|46,49|54,54 ?EEEESS??TTS?SSS?EEE??HHHHHHTHHHHTSEEE??HHH---HHHH----H 2XG2|I PF01282.14_Ribosomal_S24e_seed 70 89 !Q:6,6|10,14|29,30|34,35|42,42|57,57|66,66|74,74|77,86 Q:0,5|7,9|15,28|31,33|36,41|43,56|58,65|67,73|75,76|87,88 EEEEEE?TTS-????HHHHHHHHHTTTTS-?GGG??EEEEEE?SSSSEEEEEEEEES?HHHHHHHS?HHHHHHS-TT???-??--??SH 2XZM|P PF01283.14_Ribosomal_S26e_seed 37 127 !Q:0,4|7,7|11,13|16,16|18,20|23,24|28,30|47,47|59,60|62,64|67,70|79,79|90,93|96,100|104,109|112,116|118,126 Q:5,6|8,10|14,15|17,17|21,22|25,27|31,46|48,58|61,61|65,66|71,78|80,89|94,95|101,103|110,111|117,117 ?????TT?SSS?--SS?S???EE??TTT???EESSSSEEEEEEEESS?TTTHHHHHHHB-?S---SS????EEEEEEEE?HHHHHHTTSS????TT-----GGG??????SS???-?S???????-? 2XZM|5 PF01285.13_TEA_seed 19 660 !Q:0,338|343,343|346,346|356,363|367,370|377,381|384,388|400,401|405,405|409,425|431,432|444,449|451,452|456,464|466,468|473,480|488,490|493,496|502,516|530,532|534,535|551,552|565,565|575,596|609,615|619,620|622,629|634,643|650,651|656,658 Q:339,342|344,345|347,355|364,366|371,376|382,383|389,399|402,404|406,408|426,430|433,443|450,450|453,455|465,465|469,472|481,487|491,492|497,501|517,529|533,533|536,550|553,564|566,574|597,608|616,618|621,621|630,633|644,649|652,655|659,659 ??---------------------------------------------------------------------------------------------------------?---------------------------------?-------------------------------------------------------------------------------------------------?---------------------------------------------------------------------------------------------------SSSB?SS?EEEEEEEEE????-???TTS?--?EEEEEE?????SS?????EEEGGGTGGGS??STT?HHH-----------------HHHHS?-TTSEEEEEEEE??-???G--GGS---------S???EEEE--------EEEEESS???EE----EEEEE---------------EETTEEEEEEEEE---E??EEETTEEEEEEEEEE??HHHHHHHHHHTT?SSHHHHHHH----------------------HTTEEEEEEEEE-------SSS??E--------EEEE----------EEEEEE-?SSSS???E 4EAZ|A PF01286.13_XPA_N_seed 10 34 !Q:0,0|2,2|5,5|9,10|14,15|22,23|25,26|30,31 Q:1,1|3,4|6,8|11,13|16,21|24,24|27,29|32,33 ?S?EE?SSS??EES??SHHHHT??S??TTT??TT 1XPA|A PF01287.15_eIF-5a_seed 97 100 !Q:0,2|8,13|17,23|25,30|34,36|38,53|55,57|68,71|74,78|86,86|92,94|99,99 Q:3,7|14,16|24,24|31,33|37,37|54,54|58,67|72,73|79,85|87,91|95,98 ???EEEEE-????-TTT-------T?????-SSS???S?????----------?S---SHHHHHHHTT----SS?-???EEEEEEE-TTEEE---EEEE? 3HKS|A PF01288.15_HPPK_seed 115 202 !Q:6,10|12,12|14,14|38,40|44,45|47,47|49,53|57,61|72,73|75,75|80,80|89,89|93,93|95,96|98,99|101,104|107,108|110,116|119,119|127,129|132,150|152,156|159,165|167,167|169,181|185,185|191,191 Q:0,5|11,11|13,13|15,37|41,43|46,46|48,48|54,56|62,71|74,74|76,79|81,88|90,92|94,94|97,97|100,100|105,106|109,109|117,118|120,126|130,131|151,151|157,158|166,166|168,168|182,184|186,190|192,201 EEEEEE?----S-S?HHHHHHHHHHHHHTSTTEEEEEE???EEE??S-S----?SSS?--?-EEEEEEEEEE-?S?HHHH-HHHHHHHH-HHT-T??B-?S----TT--S------?BS?EEEEEEE---TT?--------------?---E-----ES-------S-S------------?EES?GGGGG?HHHHHHHHHH 3UDV|A PF01289.14_Thiol_cytolysin_seed 5 468 !Q:0,0|11,14|20,20|23,30|37,37|54,55|60,61|65,65|68,68|72,72|76,76|84,86|88,91|93,94|100,101|104,105|107,107|116,117|140,142|145,145|154,156|167,167|176,178|187,187|204,206|214,214|217,218|227,227|232,232|252,255|268,268|274,274|291,292|298,298|305,305|320,320|324,325|338,339|341,344|359,359|367,368|384,384|388,388|396,396|401,402|414,414|428,430|433,433|445,447 Q:1,10|15,19|21,22|31,36|38,53|56,59|62,64|66,67|69,71|73,75|77,83|87,87|92,92|95,99|102,103|106,106|108,115|118,139|143,144|146,153|157,166|168,175|179,186|188,203|207,213|215,216|219,226|228,231|233,251|256,267|269,273|275,290|293,297|299,304|306,319|321,323|326,337|340,340|345,358|360,366|369,383|385,387|389,395|397,400|403,413|415,427|431,432|434,444|448,467 ?HHHHHHHHHT????TTGGG?EE????????SEEEEE?SSEEEEEEEEEEEEEE??SSEE??SSS?SS?STT?EEE?SHHHHTT???B????B??EEEEE??TT??S-TTEEEESS??HHHHHHHHHHHHHHHHHHTSTT?-?EE?EEEEEEEE???HHHHHHHHTS?HHHHHHHH???HHHHHTTS?EEEEEEEEEEEEEEEE???SSGGGGB?TT??HHHHHHTT?BTTB?EEEEEEEEEEEEEEEEEEE????TTHHHHHHHHHH?GGGGS?HHHHHHHHTEEEEEEE??SSGGG?EEEEES?HHHHHHHHHTTSEE?TTS??EEEEEEEEETTT??B????EEEEEEEEEEEEEE?EEEEEEE??BSEEEEEEEEEEEEE?SSS?EEEEEEE?TTTT??EESSEEEEEEE?TTEEEEEEEEEEE???TT?SEEEEEEEEEE???SEEEEEEEEBSSSEEEEEEE 2BK2|A PF01290.15_Thymosin_seed 25 47 !Q:0,4|16,17|23,47 Q:5,15|18,22 ?????HHHHHHHHHHH??GGGSB???????????????-????????- 3SJH|B PF01291.12_LIF_OSM_seed 5 179 !Q:14,14|17,17|29,30|33,33|39,42|47,49|57,57|84,85|94,95|124,152 Q:0,13|15,16|18,28|31,32|34,38|43,46|50,56|58,83|86,93|96,123|153,178 HHHHHHHHHHHHHT?GG-GTHHHHHHHTT??SH-HHHTT????TTTS?-?HHHHHHT?HHHHHHHHHHHHHHHHHHHHHHHHTS??GGGHHHHT??HHHHHHHHHHHHHHHHHHHHHHHHHHHS????---??????????????????????HHHHHHHHHHHHHHHHHHHHHHHHHH 1LKI|A PF01292.15_Ni_hydr_CYTB_seed 84 338 !Q:0,6|9,19|35,37|45,50|52,52|56,118|130,131|141,141|153,157|159,175|185,200|203,221|246,247|250,250|263,285|289,289|298,299|314,314|324,337 Q:7,8|20,34|38,44|51,51|53,55|119,129|132,140|142,152|158,158|176,184|201,202|222,245|248,249|251,262|286,288|290,297|300,313|315,323 ??--???TT-----------HHHHHHHHHHHHHHH---HHHHHHS??????S?GGG?-------------------------------------------------------------?HHHHHHHHHHH--HHHHHHHHH-HHHHHHHTTTT----?S?????????????????STTTSSSSS????????????????TT-------------------THHHHHHHHHHHHHHHHHHHTTTT??SS?GGGHHHHHHHHH-----------------------HTS?THHHHHHH--HHHHHHHHHHHHHH-HHHHHHHHH????-????????? 1KQF|C PF01293.15_PEPCK_ATP_seed 128 550 !Q:0,2|7,7|9,10|20,28|31,32|36,37|40,40|44,44|48,49|52,52|55,56|64,64|73,74|81,82|84,84|88,88|107,107|123,124|133,133|141,142|148,154|160,160|162,166|176,178|186,186|190,190|206,208|220,220|228,228|231,231|241,241|243,243|245,246|248,249|251,256|261,262|272,279|283,283|290,290|294,295|298,298|303,303|310,310|313,314|318,318|325,325|327,328|331,331|336,336|339,341|345,345|350,351|354,354|356,357|370,371|376,376|378,378|387,388|392,392|394,394|399,400|403,403|412,412|418,418|425,428|434,434|438,438|442,443|445,445|458,464|467,467|470,470|477,477|480,480|483,491|495,496|513,516|520,522|536,537|539,543|546,546 Q:3,6|8,8|11,19|29,30|33,35|38,39|41,43|45,47|50,51|53,54|57,63|65,72|75,80|83,83|85,87|89,106|108,122|125,132|134,140|143,147|155,159|161,161|167,175|179,185|187,189|191,205|209,219|221,227|229,230|232,240|242,242|244,244|247,247|250,250|257,260|263,271|280,282|284,289|291,293|296,297|299,302|304,309|311,312|315,317|319,324|326,326|329,330|332,335|337,338|342,344|346,349|352,353|355,355|358,369|372,375|377,377|379,386|389,391|393,393|395,398|401,402|404,411|413,417|419,424|429,433|435,437|439,441|444,444|446,457|465,466|468,469|471,476|478,479|481,482|492,494|497,512|517,519|523,535|538,538|544,545|547,549 ???EEEE-S??HHHHHHHHS?--------TT??GGG??EE?TTS?EEE??TT?SS??GGGEEEE?STTTTTTS??TTTSSS??S?EEE?HHHHHHHHHHHHHHSTTS-EEEEEEEEESSSTTT-?EEEEEEES?HHHHHHH--HHHSB??----?HHHHH-T?--??SEEEEEETT???TTHHHHT?SSS?EEEEETTTTEEEEES???THHHHHHHHHH-HHHHTGG-GT?EEESEEEEE?T-T--S-?E------EEEE??TTSSHHHHH?------?TTS-EEEESS?EEE?-SS?EEES?SEEEEE?TT??TTT?HHHHHT?S--TT?EEES?EE-?-TTS?EETT??SS?S??EEEEEGGGSSSB??SSSB?S?EEEEEEEE??TTS?S?SEEE??HH-HHHHHHHH?EEEEE?GGGSSS-??-EEEEE?GGG?GGG??S?HHHHHHHHHHHH-------HH-HT?EEEEEE?SB?TT---------SSB??HHHHHHHHHHHHTTHH----HHS?--EEEETTTTEEEES??T-----TS?GGG 1YGG|A PF01294.13_Ribosomal_L13e_seed 6 180 !Q:0,8|10,10|15,15|17,18|40,40|42,43|46,46|48,54|56,56|59,59|63,67|69,70|79,80|88,99|118,121|125,126|128,130|132,132|136,136|142,167|170,171 Q:9,9|11,14|16,16|19,39|41,41|44,45|47,47|55,55|57,58|60,62|68,68|71,78|81,87|100,117|122,124|127,127|131,131|133,135|137,141|168,169|172,179 ?????????S?TTTT?B??TTHHHHHHHHHHHHHHHHHHT?S??SS?S???????S?SS?SSS?????S??HHHHTTTT??HHHHHHH????????????TTHHHHHHHHHHHSSSSS????TTS??S???S?SSS?IIIII??????????????????????????TT??HHHHHHHH 3J39|L PF01297.12_TroA_seed 141 792 !Q:15,16|19,20|22,34|36,36|44,45|47,47|50,51|55,60|70,73|79,83|88,88|91,94|96,96|102,109|112,112|119,125|130,137|139,181|184,537|539,542|546,546|552,552|566,573|579,581|607,607|609,609|611,621|626,626|629,631|633,634|641,644|646,646|648,649|654,664|667,668|671,673|689,690|699,700|702,703|709,711|716,716|718,720|722,724|726,732|736,736|739,763|765,770|779,782 Q:0,14|17,18|21,21|35,35|37,43|46,46|48,49|52,54|61,69|74,78|84,87|89,90|95,95|97,101|110,111|113,118|126,129|138,138|182,183|538,538|543,545|547,551|553,565|574,578|582,606|608,608|610,610|622,625|627,628|632,632|635,640|645,645|647,647|650,653|665,666|669,670|674,688|691,698|701,701|704,708|712,715|717,717|721,721|725,725|733,735|737,738|764,764|771,778|783,791 EEESSHHHHHHHHHH--HG--G-------------G-EEEEESS-?T-TS?-GGG?--???HHHHHHGGG---?SEEEE--??-TTTT-TT----T-HHHHH--------HH?SSSEEE-------ETTT--------T?---------------------------------------???BS------------------------------------?????----------------------------------------------------------------------------------------------------------????????????????????????????------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?????B???-GGG?HHHHH-HHHHHHHHHHHHH-------?GGGHH---HHHHHHHHHHHHHHHHHHHHHHHHT-T?S-?--------?EEEE-SS???H--HHHHHT----T?E--EEES?----------BT--TB???HHHHHHHHHHHHTTT??EEEEETTS??H--HHHHH---HHHH-T--?E---E-------EEE?TT------------------------?S------SHHHHHHH----HHHHHHHHH 1K0F|A PF01298.13_Lipoprotein_5_seed 37 979 !Q:0,67|74,75|77,91|96,98|100,102|106,106|109,117|123,144|155,160|162,186|189,189|192,211|213,213|215,217|220,222|244,246|248,248|257,258|268,268|274,278|280,280|293,294|298,307|312,312|314,315|318,318|324,325|328,328|330,330|333,335|340,340|343,345|348,348|350,350|371,372|378,378|380,380|382,384|386,387|390,392|395,397|414,414|417,418|424,425|429,430|432,445|447,447|460,460|468,468|472,472|480,512|516,516|523,542|546,546|552,552|554,561|563,563|577,598|605,640|647,647|650,650|658,692|696,718|722,761|769,775|778,778|780,784|786,787|799,799|803,803|806,806|811,814|820,821|825,830|846,846|849,849|852,854|859,859|866,867|876,877|879,881|883,885|887,887|890,891|894,900|914,914|924,966|978,978 Q:68,73|76,76|92,95|99,99|103,105|107,108|118,122|145,154|161,161|187,188|190,191|212,212|214,214|218,219|223,243|247,247|249,256|259,267|269,273|279,279|281,292|295,297|308,311|313,313|316,317|319,323|326,327|329,329|331,332|336,339|341,342|346,347|349,349|351,370|373,377|379,379|381,381|385,385|388,389|393,394|398,413|415,416|419,423|426,428|431,431|446,446|448,459|461,467|469,471|473,479|513,515|517,522|543,545|547,551|553,553|562,562|564,576|599,604|641,646|648,649|651,657|693,695|719,721|762,768|776,777|779,779|785,785|788,798|800,802|804,805|807,810|815,819|822,824|831,845|847,848|850,851|855,858|860,865|868,875|878,878|882,882|886,886|888,889|892,893|901,913|915,923|967,977 ????????-------------------????????---?????---???????---?----???????SEEEEE??B????-----------TTTT???B???GGG?EE??-----??SSTTS??--------------------HHHHHHHHTS?---??S??---------------------??EE?TT????????????????????B?S---SS???SSEEEEEEEEEEEEEEESSST---T?EEEEEEEE--EEEEEESSB?SEEES-----S?EEEEEEEEEEEE?-BSS---???----TTTS?S?-SS?BTTTB??BT-T?TT???BSSS?SS-??SS?S?BSEEEEEEEETTTTEEEEEE--EEBBS?S?T---T??SB???EE---EEEEEETTEEEEEEEE-TT??TTSSS??SSS??S?-------------E-EEEEEEEESTTS?EEEEEEE?TTS?EEEEEEE?????????????????????????????????EEE?EEEEEE--------------------ETT?SSEEE?B?------?S?TTEEEETTEEEES??????????????????????EEEEEE???????????????????????????????--???EEEEEE?TT?SSEEEEE-----------------------------------EEE???????????????????????EEE----------------------------------------EEEEEEB??-----TT?S?--??S?-EEEEEEEEEEE-EES-SS?EEEE????SSSSS--EEE------EEEETTTTEEEEEEE?TT?SS--?SEEE-EEEEET--TEEEEEEE??T---T???S?TT??SS???????SEEEEEEEESTTT?EEEEEEEES???-?--------------------??----????????----EEEEEEEEEEE? 3UAQ|A PF01299.12_Lamp_seed 25 363 !Q:0,131|140,141|145,145|158,159|166,169|174,175|179,180|186,187|190,190|197,200|206,206|215,215|217,220|222,222|234,240|244,246|253,253|255,256|261,261|265,265|269,269|271,271|276,276|282,288|300,301|306,308|310,362 Q:132,139|142,144|146,157|160,165|170,173|176,178|181,185|188,189|191,196|201,205|207,214|216,216|221,221|223,233|241,243|247,252|254,254|257,260|262,264|266,268|270,270|272,275|277,281|289,299|302,305|309,309 -------------------------???--------------------------------------------------------------------------------------------------------EEEEEEET--TEE-EEEEEEEEEEEE??SSSTTS??--EEEE??GGG-?EEEEE??SS-EEEEEE----EETTE-EEEEEEEE?S----S?EEEEEEEEEEE?------SSS?-?EEEEEE?S??EEEE?TTS?EEE?S?EEEE?SSSEE-------EEEEEEEEEES??BTTB-??S?????????-----------------------------------???------ 4AKM|A PF01300.13_Sua5_yciO_yrdC_seed 163 325 !Q:6,7|11,12|16,16|24,25|38,40|44,48|51,51|53,57|62,63|70,72|74,82|88,99|104,107|109,109|120,138|141,146|148,148|150,151|154,164|166,166|169,169|176,179|188,205|208,208|210,210|212,226|229,230|234,234|237,237|239,246|255,255|257,260|266,272|277,287|289,289|291,291|293,294|298,299|301,302|304,307|311,311|313,318|320,320|323,324 Q:0,5|8,10|13,15|17,23|26,37|41,43|49,50|52,52|58,61|64,69|73,73|83,87|100,103|108,108|110,119|139,140|147,147|149,149|152,153|165,165|167,168|170,175|180,187|206,207|209,209|211,211|227,228|231,233|235,236|238,238|247,254|256,256|261,265|273,276|288,288|290,290|292,292|295,297|300,300|303,303|308,310|312,312|319,319|321,322 HHHHTT??EEE??SSS?EEEEETT-?HHHHHHHHHHHT??-TTS--???EE?S-----SHHH--HHHHEE---S?-------?HHHHH------------HHHH----H?SSSEEEEEEE------------------?TT------S?H--HH-----------H-TT?SEEEEE????HHHHHHHH------------------HH-T-S---?-----------EE??BSS?TT-S---???-?SHHHHHHH-H----TTTSS-------EEEE??------?-?S-S?S??EEE--E-?S----SSS?E------E-EE?? 3TTD|A PF01301.14_Glyco_hydro_35_seed 37 374 !Q:8,10|16,16|21,22|38,39|45,46|51,51|57,60|64,64|66,66|75,75|80,80|86,87|89,91|99,100|107,108|111,111|116,116|119,119|138,139|146,146|148,148|160,164|167,169|175,175|186,188|190,190|196,196|206,210|215,216|225,228|231,236|243,247|256,260|267,267|269,271|276,287|290,290|303,309|319,320|322,323|326,326|328,328|335,337|343,343|346,347|350,350|353,353|357,357|359,360 Q:0,7|11,15|17,20|23,37|40,44|47,50|52,56|61,63|65,65|67,74|76,79|81,85|88,88|92,98|101,106|109,110|112,115|117,118|120,137|140,145|147,147|149,159|165,166|170,174|176,185|189,189|191,195|197,205|211,214|217,224|229,230|237,242|248,255|261,266|268,268|272,275|288,289|291,302|310,318|321,321|324,325|327,327|329,334|338,342|344,345|348,349|351,352|354,356|358,358|361,373 SEEETTEE???EEEEE?GGGS?-GGGHHHHHHHHHHTT??EEEEE??HHHH?SBTTB-???SGG-G?HHHHHHHH-HHTT?EEEEE??S???TTBGGGG??GGGGGS--SS?SSSS?HH-HHHHHHHHHHHHGGGTGG--GBGGGT-S?EEEEESSSSGG-----GT???HHHHH-HHHHHHHHTT??-S?EEEEE?SSHHHHHHH---??GGGT-?EEEEEESS?---HH------HHHHHH-----HHHHHHTT?????EEEEEE?S???BTTS-----?-?????HH-HHHHHHHHHHHH-------SEEEEEEEE??B??TT?B?EEEETT---EEEEB?SB??TT?SB?TTS?B?-HHHHHHHHHHHHH 1TG7|A PF01302.20_CAP_GLY_seed 146 171 !Q:2,3|6,6|9,17|22,22|30,35|38,38|40,40|42,42|46,73|75,87|89,94|101,101|104,107|109,119|121,124|129,130|132,132|137,137|139,152|155,159|165,165 Q:0,1|4,5|7,8|18,21|23,29|36,37|39,39|41,41|43,45|74,74|88,88|95,100|102,103|108,108|120,120|125,128|131,131|133,136|138,138|153,154|160,164|166,170 SS-?EE-EE?-------?SSSS?EEEEEEE------EE-E?S-SSS----------------------------S-------------E------EEEEEE-SS----S----?-----?S----BBSE--E-TTEE?S--??--------?-TT-----TEEEE?GGGEE 2COW|A PF01303.12_Egg_lysin_seed 24 133 !Q:0,1|31,36|49,49|72,72|74,76|90,91|93,95|99,99|108,116|126,126|130,132 Q:2,30|37,48|50,71|73,73|77,89|92,92|96,98|100,107|117,125|127,129 ??HHHHHHHHHHHHHHHHHHHHHHHHHHGGG?----?HHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHTS-S???THHHHHHHHHHHH--T???HHH-HHHHHHTT---??????HHHHHHHHS?GGG??? 1LYN|A PF01306.14_LacY_symp_seed 4 415 !Q:0,0|5,5|22,22|39,41|71,72|75,75|103,103|139,139|165,165|188,192|196,196|204,209|219,219|243,243|288,288|310,312|343,343|378,378|402,403|405,405|408,408|413,414 Q:1,4|6,21|23,38|42,70|73,74|76,102|104,138|140,164|166,187|193,195|197,203|210,218|220,242|244,287|289,309|313,342|344,377|379,401|404,404|406,407|409,412 ?TTTT?HHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHH???HHHHTTHHHHHHHHHHTTHHHHHHHHTSS??SS?THHHHHHHHTTSTTTTTTTHHHHHTTT?HHHHHHTTGGGTTTTTTTHHHHHHHHHHHHHHHSS?STTTSTTTTHHHHHHHHHHTTHHHH?HHHHHHHHHHTTHHHHHHTTSS?????TTS?SSTTSSS??????HHHHHHHTT?HHHHHHHHHHTTHHHHHHHHHTT-THHHHHHTSSSHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHHHHH???TTTTTHHHHTSTTTHHHHHHHHHHHHGGGS?GGGHHHHHHHTTTTTHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHTHHHHTTHHHHS??S?SS?SSSS?? 2CFP|A PF01310.13_Adeno_PVIII_seed 17 282 !Q:0,1|3,5|8,11|16,20|23,24|27,27|30,30|32,39|41,42|69,71|76,76|79,80|85,96|99,99|102,102|110,118|123,210|213,213|215,218|221,224|226,226|228,229|231,233|235,237|246,250|255,256|258,258|264,264|270,271|276,281 Q:2,2|6,7|12,15|21,22|25,26|28,29|31,31|40,40|43,68|72,75|77,78|81,84|97,98|100,101|103,109|119,122|211,212|214,214|219,220|225,225|227,227|230,230|234,234|238,245|251,254|257,257|259,263|265,269|272,275 ??S???EE????SSSS?????EE??SS?EE?S--------S??HHHHHHHHHHHHHHHHHHHHTTTTTS???SSSS?SS??TTTS??????---???EE?SS?TTTSHHH---------HTTT????????-----------????-------???????????????-???????------???????--??????--???????----?SS?S-???EE????S?S--S???S???SHHHHHSS?????SSTT-?S?SSSSS?TTSSS??SSSS?????? 3IYN|O PF01312.14_Bac_export_2_seed 16 358 !Q:0,241|256,260|266,269|272,272|288,289|293,293|296,296|319,320|324,324|335,336|341,342 Q:242,255|261,265|270,271|273,287|290,292|294,295|297,318|321,323|325,334|337,340|343,357 -----------------------------------------------------------------------------------------------------------------------------------???------------------------------------------------------------------------------------------??????????????????HHHHHHHHHHHHHH?-???HHHHH----HT?SEEEEETTTEEEEEE??TTT?SS?EEEEEEETTHHHHHHHHHHHHT??EEE?HHHHHHHHHH??TTSB??GGGHHHHHHHHHHHH 3BZV|A PF01314.13_AFOR_C_seed 112 714 !Q:13,15|22,24|31,31|36,36|42,47|51,53|59,62|65,68|70,81|91,91|95,101|105,105|110,121|124,124|127,128|131,131|137,172|175,184|187,202|205,207|209,210|221,241|243,245|262,262|282,284|286,286|291,296|300,304|307,307|322,322|324,324|332,332|341,342|344,345|348,350|352,356|359,364|366,369|372,372|374,375|377,378|382,382|384,386|388,390|398,398|403,403|406,407|410,419|427,434|436,449|452,454|457,470|472,482|487,487|500,504|510,511|517,519|521,551|556,586|596,600|608,608|622,622|625,630|632,637|643,645|649,650|654,663|667,668|672,682|696,698|702,704|713,713 Q:0,12|16,21|25,30|32,35|37,41|48,50|54,58|63,64|69,69|82,90|92,94|102,104|106,109|122,123|125,126|129,130|132,136|173,174|185,186|203,204|208,208|211,220|242,242|246,261|263,281|285,285|287,290|297,299|305,306|308,321|323,323|325,331|333,340|343,343|346,347|351,351|357,358|365,365|370,371|373,373|376,376|379,381|383,383|387,387|391,397|399,402|404,405|408,409|420,426|435,435|450,451|455,456|471,471|483,486|488,499|505,509|512,516|520,520|552,555|587,595|601,607|609,621|623,624|631,631|638,642|646,648|651,653|664,666|669,671|683,695|699,701|705,712 HHHHHHHHHHHHH---HSHHHH---THHHHH?GGGH-HHHHH------HTT???BTTTT----BS??--T------------TGGGGSHHH-HHH-------HTE-EEEE----?------?TT?SS??EE-EEEET------------------------------------TT----------EE----------------EE???H--HHHHHHTGGG---------------------T???HHHHHHHHHHHHHHTB?HHHHHHHHHHHHHHHHTTS---S?HHHH------TTS????-TT?THHHHHHHHHHHTT?T-THHHHTT?HHHHHHHT--T-?GG---G?--?-EE------T----TE-E??S??GGG?H---H---HHHHHHH?TTSS?SG--GG--------?-THHHHTT-------?S--------------SS???TT------------??S-----------HHHH-HHHHHHHHHHHH-----HHHHT??GGGGT---T-----------------------------??HHHH-------------------------------HHHHHHHHT??-??HHHHHHH-HHHHHHHHHHHHH-HH------T----??HHHHS???HHH--HHS-------???SST--TTT?-----???--HHHHHHHHHHHHT??-TTS???HHHHHHHT? 1B4N|A PF01315.17_Ald_Xan_dh_C_seed 30 118 !Q:2,2|4,5|10,11|15,15|23,23|35,35|49,49|53,53|56,56|62,66|69,69|72,77|80,81|85,85|89,89|109,109|116,117 Q:0,1|3,3|6,9|12,14|16,22|24,34|36,48|50,52|54,55|57,61|67,68|70,71|78,79|82,84|86,88|90,108|110,115 TT?S??GGGS??BTT?EEEEEEE?SSSSEEEEEEE?TTGGGSTTEEEEE?GGG?SS?SEEST-----TS?EE------SS??SEE?STT?EEEEEEESSHHHHHHHHHT?EEEEEE?? 1DGJ|A PF01316.16_Arg_repressor_seed 10 72 !Q:0,3|17,19|33,37|50,50|55,56|60,60|65,65|68,68 Q:4,16|20,32|38,49|51,54|57,59|61,64|66,67|69,71 ????HHHHHHHHHHHHS???SHHHHHHHHHHTT??-??HHHHHHHHHHTT?EEEE-?SSS?EEEE?TT?SSS 3V4G|A PF01318.13_Bromo_coat_seed 3 190 !Q:0,46|60,62|65,65|70,74|78,78|85,85|93,94|97,97|100,101|103,103|111,112|122,122|124,125|127,127|132,134|144,144|162,164|178,179|185,189 Q:47,59|63,64|66,69|75,77|79,84|86,92|95,96|98,99|102,102|104,110|113,121|123,123|126,126|128,131|135,143|145,161|165,177|180,184 ???????-???????????????????????????????????????SSEEEEEEEEEEE???TT?EEEE?????GGG?SHHHHT?BEEEEEE??EE?TT??S?EEEEEEE??SSGGGHHHH?S??B?SSSS???EEETTTTTT?BHHHHHHHEEEEEEESS???EEEEEEEEEEEEE??SGGGS????? 1JS9|A PF01320.13_Colicin_Pyocin_seed 29 99 !Q:0,4|6,7|27,32|39,43|55,56|66,67|69,71|74,75|93,96|98,98 Q:5,5|8,26|33,38|44,54|57,65|68,68|72,73|76,92|97,97 ??-??S--SGGGSBHHHHHHHHHHHHH?---??SSHHHH-----HHHHHHHHHHH??SSHHHHHHS??S---SS??SHHHHHHHHHHHHHHHT????B? 2GZJ|A PF01321.13_Creatinase_N_seed 170 251 !Q:13,15|21,22|24,35|43,54|58,58|62,62|64,69|72,72|74,76|78,78|80,98|102,103|114,121|128,128|131,131|134,154|163,171|177,188|192,192|194,196|202,206|212,214|222,228|230,231|237,237|239,242 Q:0,12|16,20|23,23|36,42|55,57|59,61|63,63|70,71|73,73|77,77|79,79|99,101|104,113|122,127|129,130|132,133|155,162|172,176|189,191|193,193|197,201|207,211|215,221|229,229|232,236|238,238|243,250 HHHHHHTTHHHHT--?SEEEE??H------------HHHHHHH??---------?SSS?EEE-E------ES-S?--E-E-------------------EEE?-GGGHHHHHHH--------STTSEE-EE?SS--------------------?HHHHHHHH---------HHHHT-----------?SEE-E---EETTT-----SBHHH---HHHHHHH?-----?S--EEEEE?S----HHHHHHTS 2HOW|A PF01322.15_Cytochrom_C_2_seed 95 143 !Q:2,4|6,6|15,15|18,18|25,25|31,31|37,39|61,65|68,69|74,79|81,81|86,86|111,111|115,117|119,119|133,133 Q:0,1|5,5|7,14|16,17|19,24|26,30|32,36|40,60|66,67|70,73|80,80|82,85|87,110|112,114|118,118|120,132|134,142 HH---H-HHHHHHHH-HH-HHHHHH-HHHHH-HTTSS???HHHHHHHHHHHHHHHTSGGGS--?-?TT??SSTT----??B?THHH-HTHHHHHHHHHHHHHHHHHHHHHH-HHT--?H-HHHHHHHHHHHHH-HHHHHHHHB 2BC5|A PF01323.15_DSBA_seed 30 246 !Q:6,6|9,9|27,45|52,53|63,64|66,67|71,77|97,102|104,114|124,125|129,130|147,149|152,152|156,157|167,169|173,175|183,185|204,205|213,215|218,223|225,229|246,246 Q:0,5|7,8|10,26|46,51|54,62|65,65|68,70|78,96|103,103|115,123|126,128|131,146|150,151|153,155|158,166|170,172|176,182|186,203|206,212|216,217|224,224|230,245 EEEEEE?TT?HHHHHHHHHHHHHHHHH----------------?-?EEEEEE??HHHHHHHHT??S??GGG------?HHHHHHHHHHHHHHHHHHT??????S?----?---??HHHHHHGGG??SHH--HHHHHHHHHHHHHHHS???TT?TTH--HHHHHHHHT?-?HHH---HHHHHHS---HHHHHHHHHHHHHHHHTT??SSSEEEE---TT------E-----EEESGGGHHHHHHHHH- 3L9V|A PF01324.14_Diphtheria_R_seed 3 154 !Q:0,1|3,3|6,7|29,30|45,45|49,49|55,55|63,63|67,67|77,77|95,95|103,103|113,115|117,119|123,123|125,126|150,150 Q:2,2|4,5|8,28|31,44|46,48|50,54|56,62|64,66|68,76|78,94|96,102|104,112|116,116|120,122|124,124|127,149|151,153 ??S?SS??EEETTEEEEESSGGGGEEETT??SEEEEEEEEEESSS?EEE?EEEEE?BTTTEEE?TTT?EEEETTEEE?EEEEEETTTEEEEEESS?EEEBTTB?EEEEEEEEE???S???TTT?S??EEEEEEEEEEETTEEEEEEEEEE?EEE 1F0L|A PF01325.14_Fe_dep_repress_seed 10 61 !Q:0,2|18,18|23,24|34,35|54,60 Q:3,17|19,22|25,33|36,53 ???HHHHHHHHHHHHHHH-HHSS??HHHHHHHTT??HHHHHHHHHHHHHTTSEE??????? 1DDN|A PF01326.14_PPDK_N_seed 101 643 !Q:6,7|9,9|21,29|37,42|47,47|49,49|52,53|59,62|65,74|77,78|89,105|107,108|129,129|131,136|143,145|150,159|163,164|171,189|191,194|199,204|207,229|231,243|245,245|247,247|250,251|255,255|257,267|284,284|292,299|303,324|332,334|336,343|355,355|357,366|369,372|375,375|384,385|395,397|403,404|411,424|428,429|435,439|445,445|447,454|465,483|490,492|495,495|497,527|530,534|542,549|557,558|562,569|572,573|579,579|583,592|601,639|641,641 Q:0,5|8,8|10,20|30,36|43,46|48,48|50,51|54,58|63,64|75,76|79,88|106,106|109,128|130,130|137,142|146,149|160,162|165,170|190,190|195,198|205,206|230,230|244,244|246,246|248,249|252,254|256,256|268,283|285,291|300,302|325,331|335,335|344,354|356,356|367,368|373,374|376,383|386,394|398,402|405,410|425,427|430,434|440,444|446,446|455,464|484,489|493,494|496,496|528,529|535,541|550,556|559,561|570,571|574,578|580,582|593,600|640,640|642,642 GGGHHH--H-HHHHHHHHHHH---------HHHGGGT?-????EEEE?H-HH--HHHHH----TG----------GG--HHHHHHHHHH-----------------S??TTSHHHHHHHHHHHHHHHHT-S???---HHHHHH---HHHH----------HHH--HHHHTS-------------------S????EEEE------EE-----------------------E????????--???S?S?EE--EEE?S-----------HHHHHHHHHHHHHHTT?HHHHHHH--------HHH?-???-------------????EEEEEEE???T--------TSSEEEEEESS?T----------TT?-??SE-EEEEEEES-?THHHHHTSS-??EEEEE--EHHHHH--------------TTS??EEEEE?????EEEEE?S?------?SSSTTEEEEE??-----------------HHHHTS--?SS?H-------------------------------HH-----HHHHHHH--------HHHHHHH--HTS------?-EE--EEEEE?TTT-----??---EEEEEEEE??????????????????????-------------????B?B 1VBG|A PF01327.16_Pep_deformylase_seed 130 287 !Q:0,5|8,8|10,13|17,17|19,19|21,22|24,32|35,35|44,45|48,50|56,56|58,70|73,73|81,84|90,93|96,96|101,102|105,123|131,169|171,178|181,181|183,189|196,197|202,206|208,213|221,221|228,229|233,233|238,238|240,242|244,244|246,252|254,254|269,270|275,279|281,281 Q:6,7|9,9|14,16|18,18|20,20|23,23|33,34|36,43|46,47|51,55|57,57|71,72|74,80|85,89|94,95|97,100|103,104|124,130|170,170|179,180|182,182|190,195|198,201|207,207|214,220|222,227|230,232|234,237|239,239|243,243|245,245|253,253|255,268|271,274|280,280|282,286 ??????TT?G----GGG?B?B??S---???---HH-HHHHHHHH--HH---HHHHT-T------------?SE-EEGGGGT?--?BSEEE----EE?STTS??EE-------------------EEEEEEE---------------------------------------E--------ES?S------?EEEEEE??TTST-----T----??EEEEEES?EEEEEE?-TTS?EEEE-E---E?H-------H-HHHHHHHHHHHHBT??GGGG-----S?HHHHH 2AI9|A PF01328.12_Peroxidase_2_seed 2 319 !Q:0,21|25,25|31,31|34,41|44,47|49,49|62,62|65,65|69,69|82,82|84,84|106,107|119,119|123,123|126,126|129,129|133,134|139,139|144,148|151,152|166,166|170,170|190,190|194,197|204,204|215,215|225,226|241,242|247,250|253,253|255,255|270,271|274,275|278,279|282,282|285,295|298,312|315,317 Q:22,24|26,30|32,33|42,43|48,48|50,61|63,64|66,68|70,81|83,83|85,105|108,118|120,122|124,125|127,128|130,132|135,138|140,143|149,150|153,165|167,169|171,189|191,193|198,203|205,214|216,224|227,240|243,246|251,252|254,254|256,269|272,273|276,277|280,281|283,284|296,297|313,314|318,318 --------------------??GGG?TTTTT?SS????????TT????S?HHHHHHHHHTSS?TT?EEE?HHHHHHHHHHHH?B?HHHHHHHHHHHHHHHHHHHSS??TTSEEESGGGG?TTT-TS?SS?SSS??TTBT?SSTT?????SS??HHHHHHHHGGGTT?SEE?HHHHHHHHHHHHHHHHHHB?TTT????HHHHHH-HHHHHHHHHB?TTSTTTTTS??EEHHHHHHHHHHSS??GGGT????SS?B?HHHHHHHHHHHHHS??SS??SS??TT?SS???????????TT???????????????TT???T 2J19|A PF01329.14_Pterin_4a_seed 136 136 !Q:0,5|8,9|17,18|21,21|27,31|33,34|37,37|39,41|43,52|55,55|60,60|63,63|71,73|88,90|95,95|105,105|110,113|115,116|118,119 Q:6,7|10,16|19,20|22,26|32,32|35,36|38,38|42,42|53,54|56,59|61,62|64,70|74,87|91,94|96,104|106,109|114,114|117,117|120,135 ?-?--?SB??HHHHHHH--HH-HHHHT-----T?-EE?S---S----------SS?EEEE-EE?SSHHHHH---HHHHHHHHHHHHHT???EEEE-ETTEEEEEE?BTTT----T--B-?BHHHHHHHHHHHHHHT 2V6T|A PF01330.16_RuvA_N_seed 33 68 !Q:0,2|22,22|30,31|38,40|43,43|59,62 Q:3,21|23,29|32,37|41,42|44,58|63,67 ???EEEEEEEEEETTEEEEEET-TEEEEEE??GGGGGS???TT-SEEEEEEEEEEETTE----EEEEE 1D8L|A PF01331.14_mRNA_cap_enzyme_seed 12 215 !Q:4,5|17,17|25,25|36,36|40,41|43,43|49,49|53,53|58,65|68,69|76,79|92,92|95,96|98,99|117,118|125,126|147,147|151,151|153,157|163,165|174,177|185,185|188,188|201,202|213,214 Q:0,3|6,16|18,24|26,35|37,39|42,42|44,48|50,52|54,57|66,67|70,75|80,91|93,94|97,97|100,116|119,124|127,146|148,150|152,152|158,162|166,173|178,184|186,187|189,200|203,212 EEEE??HHHHHHTTSSS?EEEEEEE?SEEEEEEEEE?TTT??E-EEEEE?SSS?EEEE????????SS??SSGGGT????SEEEEEEEEEEE?TT--T??EEEEEEEEEEEEETTEE-?SSSBHH--HHHHHHHHTTHHHHHHHHHH?STT?S?--??SEEEE???EEGGGHHH----HHHHHTT?SS?EEEEEEEESSSB??SSSEEEEEEE?? 3RTX|A PF01333.14_Apocytochr_F_C_seed 49 142 !Q:3,4|6,6|18,19|22,35|37,42|48,48|50,50|54,54|61,61|65,65|67,71|74,74|77,77|80,80|84,89|101,102|137,137 Q:0,2|5,5|7,17|20,21|36,36|43,47|49,49|51,53|55,60|62,64|66,66|72,73|75,76|78,79|81,83|90,100|103,136|138,141 TTS??B?SSSEEEEEEEE??TT--------------T----??EEEEE-E?SSS?EEEEEE?SSS?B?--??TT?EE?TT?BSB??????EEEEEEEEEEE??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HTSH 1E2V|A PF01335.16_DED_seed 37 95 !Q:7,7|13,13|26,28|32,32|36,37|41,42|51,51|58,59|62,67|78,79|93,95 Q:0,6|8,12|14,25|29,31|33,35|38,40|43,50|52,57|60,61|68,77|80,92 HHHHHHH-HHTTS?HHHHHHHHHHTT---TTS?HHH--HHH??SSHHHHHH-HHHTTS??SS??----HHHHHHHHHT??HHHHHHHHHHHHT??- 4IZ7|B PF01336.20_tRNA_anti-codon_seed 640 177 !Q:4,4|11,27|31,31|39,43|49,51|53,58|65,65|69,88|98,104|107,107|113,114|120,131|135,136|138,153|167,172 Q:0,3|5,10|28,30|32,38|44,48|52,52|59,64|66,68|89,97|105,106|108,112|115,119|132,134|137,137|154,166|173,176 EEEE-EEEEEE-----------------EEE-TTEEEEE-----EEETT---E------EEEEEE?TTS--------------------HHHHHHHHH??-----TT?EEEEE--EEEEE?----------?GGG??T----------------TSTTTTEEEEEEE------EEEE 1EFW|A PF01337.13_Barstar_seed 52 107 !Q:7,8|22,22|24,26|29,30|44,55|57,57|81,83|96,100|106,106 Q:0,6|9,21|23,23|27,28|31,43|56,56|58,80|84,95|101,105 EEEETTT??SHHHHHHHHHHHT-T??-TT??SSHHHHHHHHTTT------------S?SSEEEEEETHHHHHHTTTTTHHH---HHHHHHHHHHHT---??EEEEE? 1B3S|D PF01338.13_Bac_thur_toxin_seed 7 237 !Q:0,23|32,32|53,54|58,59|61,61|65,65|76,76|79,80|83,83|114,114|123,123|137,137|189,189|196,197|200,200|217,220|222,236 Q:24,31|33,52|55,57|60,60|62,64|66,75|77,78|81,82|84,113|115,122|124,136|138,188|190,195|198,199|201,216|221,221 ???--???????????????????SEEEEEES?GGGHHHHHHHHHHHGGGEEE??TTT?-S?EEE?HHHHHHHHHH?SS??EE-EEEEEEEEEEEEEEHHHHHHHHHHHHHHHH?HHHHHHTH-HHHHHHHHHHHSS?GGGTTSTTEEEEEEETTEEEEEEEEEEEEESTTTTTEEEEEEEEEEEEESS?HHHHTT??TT?EEEEEEEEEEEEEEEE????S??????????????? 1VCY|A PF01339.12_CheB_methylest_seed 180 252 !Q:5,5|7,7|10,10|22,26|28,28|30,35|42,44|47,47|60,60|67,69|72,73|75,78|80,82|88,89|93,93|97,107|109,116|120,122|126,135|142,148|152,156|158,159|161,161|163,163|179,179|184,184|186,186|203,203|205,205|208,209|212,212|214,214|217,217|219,220|229,229|232,234|239,239|248,248 Q:0,4|6,6|8,9|11,21|27,27|29,29|36,41|45,46|48,59|61,66|70,71|74,74|79,79|83,87|90,92|94,96|108,108|117,119|123,125|136,141|149,151|157,157|160,160|162,162|164,178|180,183|185,185|187,202|204,204|206,207|210,211|213,213|215,216|218,218|221,228|230,231|235,238|240,247|249,251 EEEEE-E?TT-HHHHHHHHHTT---??T-T??----EEEEEE???TT-HHHHHHHHHHHH?SSEEEE-??TT?-B?--?T---TEEEE??TTS-EEE-----------E--------EEE---TTE----------EEEEEE---????SSS?----S--S?H-HHHHHHHHHHTGGGE-EEEE?S?SSSTTHHHHHHHHHHT?E-EE--EE?G-GG?S??HHHHHHHT-TT-??SEEE?HHHHHHHH-HHH 1A2O|A PF01340.15_MetJ_seed 3 104 !Q:0,8|10,10|18,19|49,50|66,71|80,80|82,82|84,84|96,97|101,103 Q:9,9|11,17|20,48|51,65|72,79|81,81|83,83|85,95|98,100 ?????????S?SEETTEE??EEEEEEEEEHHHHHHHHHHHHHHHHTTBS??SHHHHHHHHHHHHHH??????GGGGBTTS?S?S?HHHHHHHHHTT??TTT??? 1MJQ|A PF01341.12_Glyco_hydro_6_seed 74 497 !Q:0,1|6,6|9,22|34,34|37,39|43,44|51,53|57,57|61,62|74,75|80,81|89,91|94,94|98,98|102,103|105,106|108,108|111,111|129,143|148,148|158,158|161,161|169,169|172,172|175,176|180,183|185,185|191,191|201,201|210,210|218,228|233,233|254,256|260,261|269,272|274,275|278,279|282,282|287,288|300,300|302,302|311,327|338,340|343,392|398,398|401,404|409,409|412,416|418,418|427,427|429,431|433,433|436,437|439,440|445,452|457,460|469,470|472,472|476,476|479,482|485,488|492,495|497,497 Q:2,5|7,8|23,33|35,36|40,42|45,50|54,56|58,60|63,73|76,79|82,88|92,93|95,97|99,101|104,104|107,107|109,110|112,128|144,147|149,157|159,160|162,168|170,171|173,174|177,179|184,184|186,190|192,200|202,209|211,217|229,232|234,253|257,259|262,268|273,273|276,277|280,281|283,286|289,299|301,301|303,310|328,337|341,342|393,397|399,400|405,408|410,411|417,417|419,426|428,428|432,432|434,435|438,438|441,444|453,456|461,468|471,471|473,475|477,478|483,484|489,491|496,496 ??HHHH-HH--------------HHTSTTGGGTT-TS???EEE-?STHHHH???BTT-TBT??HHHHHHHHHHH--HTTS?-EEEEEEE???TT?STT?STT??S--S?TT?HHHHHHHTHHHHHHHHH---------------TTTT?TTEEEEEEE?TT?TTHHHHS?SS-SS??HHH----H-HHHHS?HHHHHHHHH-HHHHHTST-TEEEEEE--------???HHHH?SHHHHHHHHHHHHHHHTSTT??-GGG??EEEESTT????S??TT??TT?BSSS--SBGGGSTTTTT?S?SSHHHHHH-----------------HHHHHHHHHT?-?TT?-------------------------------------------------EEEEE?TT????STTS?SS?????S-HHHHHHHH?S???S?TT??S--SBTT?-??????EEEE----ETTEEEEE??S?TTB?SS?---SS????SSS????G- 3VOG|A PF01342.16_SAND_seed 27 123 !Q:0,1|3,4|7,9|30,30|37,38|40,67|71,72|78,78|87,87|89,89|93,94|99,99|102,107|122,122 Q:2,2|5,6|10,29|31,36|39,39|68,70|73,77|79,86|88,88|90,92|95,98|100,101|108,121 ??S??GG---GSEEEEEETTEEEEEEHHHH-TTGGGS??E----------------------------EET--TTEEE?HHHHHHHH-T?STT??HHHH?EE------TTEEHHHHHHHSSS? 1OQJ|A PF01343.13_Peptidase_S49_seed 20 159 !Q:5,7|33,33|36,36|40,43|50,50|59,59|74,76|80,82|110,111|119,119|122,124|141,142|154,154 Q:0,4|8,32|34,35|37,39|44,49|51,58|60,73|77,79|83,109|112,118|120,121|125,140|143,153|155,158 HHHHH???EEEEEEEEEETHHHHHHTTSSEEEE?TT?EEE????EEEEEE?HHHHHHHT?EEEEEESSTTTTTT--?TTS???HHHHHHHHHHHHHHHHHHHHHHHHHHT??HHHHHHH?SS--?EEEHHHHHHTTSSSEE??HHHHHHHHHHH?GGGT 3BEZ|A PF01344.20_Kelch_1_seed 207 69 !Q:0,1|4,4|17,18|20,20|22,39|43,45|53,57|59,60|64,67 Q:2,3|5,16|19,19|21,21|40,42|46,52|58,58|61,63|68,68 ??BS?EEEEETTEEEEE??B?S------------------SSB???EEEEETT-----T??EEE????S 1U6D|X PF01346.13_FKBP_N_seed 121 157 !Q:0,29|40,40|52,63|76,77|80,82|85,85|93,95|113,114|117,123|147,147|149,149|152,152 Q:30,39|41,51|64,75|78,79|83,84|86,92|96,112|115,116|124,146|148,148|150,151|153,156 -----------????----------?????HHHHHHHHHH-HHHHHHHHHHT??--------??HHHHHHHHHHHH--HT???SS?HHHHHHH---HHHHHHHHHHHHHHHHH--HH-------HHHHHHHHHHHHHHHHHSTTEEE?T-TS?EEEE 3B09|A PF01347.17_Vitellogenin_N_seed 44 897 !Q:0,1|18,18|21,21|40,49|73,81|85,86|88,97|99,99|109,109|119,119|125,126|130,130|145,150|153,153|160,179|196,196|199,218|237,238|243,243|245,245|247,248|251,251|258,259|261,262|279,280|296,296|299,299|303,305|322,325|327,334|336,338|341,344|350,530|533,533|536,538|542,542|546,557|568,568|571,571|575,576|583,583|595,595|610,627|642,642|657,658|660,660|662,662|677,681|694,694|700,700|722,743|746,747|760,761|768,768|784,784|801,807|809,809|824,825|829,829|843,843|847,847|850,851|864,866|880,880|882,884|897,897 Q:2,17|19,20|22,39|50,72|82,84|87,87|98,98|100,108|110,118|120,124|127,129|131,144|151,152|154,159|180,195|197,198|219,236|239,242|244,244|246,246|249,250|252,257|260,260|263,278|281,295|297,298|300,302|306,321|326,326|335,335|339,340|345,349|531,532|534,535|539,541|543,545|558,567|569,570|572,574|577,582|584,594|596,609|628,641|643,656|659,659|661,661|663,676|682,693|695,699|701,721|744,745|748,759|762,767|769,783|785,800|808,808|810,823|826,828|830,842|844,846|848,849|852,863|867,879|881,881|885,896 ??BTEEEEEEEEEEEEEE?SS-TTSEEEEEEEEEEEEEEE?---------SSSEEEEEEEEEEEEEEEEESSS-------??EEE??T----------T?HHHHHHHTS?EEEEEETTE-EEEEE??TTS?HHHHHHHHHHHHHT???-??TT?SEEEEE--------------------EEETTEEEEEEEEEEE?SS--------------------SSEEEEEEEEEEEEEEEE??EEES?T-T-?EE?HHHHHH??S--EEEEEEEEEEEEEETT--EEEEEEEEEEEEEEE?SS?GGG-??EEEEEEEEEEEEEEEE??--S????????B???SS????TTHHH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HS?SS???TTS?HHH------------HHHHHHHHHH-HH?SSS??TTHHHH-HHHHHHHHTTS?HHHHHHHHHHHTTS------------------HHHHHHHHHHHHHH?SHHHHHHHHHHHHT--T?S?HHHHHHHHHHHHHT?-???HHHHHHHHHHHT?HHHHT?HHHHHHHHHHHHHHHHHHHTT---------------------?SS??GGGTHHHHHHHH--HHHHTT?HHHHHHHHHHHHHHT?GGGHHHHHTTSTTSSS?---???S?HHHHHHHHHTTTTG--GGT?HHHHHHHHHHHHH?TTS?HH--HHHHHHHHHHHT???HHHHHHHHHHHTT?S--?HHHHHHHHHHHH- 1LSH|A PF01351.13_RNase_HII_seed 14 237 !Q:6,6|9,9|13,13|28,29|36,43|57,68|78,78|84,86|93,93|114,114|116,117|127,128|131,131|146,146|153,153|167,167|183,183|195,200|223,223|225,226|230,230 Q:0,5|7,8|10,12|14,27|30,35|44,56|69,77|79,83|87,92|94,113|115,115|118,126|129,130|132,145|147,152|154,166|168,182|184,194|201,222|224,224|227,229|231,236 EEEEEE?SS?SBS?EEEEEEEEEGGGHH--HHHTTT????????HHHHHHHHHHHHH------------HSEEEEEEE?HHHHH---HHTTTS?HHHHHHHHHHHHHHHHHHHT-T??SSEEEEEEE??SS?HHHHHHHHHHHHHH-HHTTTT?EEEEEEETTGGGT?HHHHHHHHHHHHHHH-HHHHHHHHHTS----??TTSSTTSHHHHHHHHHHHHHHS-S??TTB?TTSHHH 3P56|A PF01352.22_KRAB_seed 69 41 !Q:0,5|8,10|18,18|36,38|40,40 Q:6,7|11,17|19,35|39,39 ??????TT???HHHHHTS?HHHHHHHHHHHHHTTTS???S? 1V65|A PF01353.17_GFP_seed 27 242 !Q:0,2|4,4|38,39|49,49|51,51|54,54|62,64|70,71|75,78|87,87|89,91|103,103|116,118|122,126|136,138|147,147|152,154|157,157|165,166|181,181|184,184|199,207|221,221|225,225|238,239 Q:3,3|5,37|40,48|50,50|52,53|55,61|65,69|72,74|79,86|88,88|92,102|104,115|119,121|127,135|139,146|148,151|155,156|158,164|167,180|182,183|185,198|208,220|222,224|226,237|240,241 ???S?SSEEEEEEEEEEETTEEEEEEEEEEEETTTTEE--EEEEEEEES?S?SS?THHHHTT???TTSSB??TTS??--HHHHTTTT?E---EEEEEEEETTS?EEEEEEEEEEET---TEE-----EEEEEEEEE???TTSTTTTT?EEEE-??EE-EEEEEET--TEEEEEEEEEEEET-TS?EEEEEEEEEEEESS???-???--SEEEEEEEEEEEE?TTS-SEEEEEEEEEEE??SS 2ZO7|A PF01355.12_HIPIP_seed 43 81 !Q:10,10|13,13|17,21|24,32|35,36|45,45|47,49|51,51|60,61|64,66|74,74|76,76|79,80 Q:0,9|11,12|14,16|22,23|33,34|37,44|46,46|50,50|52,59|62,63|67,73|75,75|77,78 TTSHHHHHTT?BS?GGG??--?TT??-------TT??GGGBTTBS?T---T?SSEEEBTT--ST---TEEEETT?B?TT?? 3H31|A PF01356.14_A_amylase_inhib_seed 6 69 !Q:0,1|7,7|12,12|20,21|25,25|35,36|38,40|44,44|47,49|53,54|56,56|60,61|68,68 Q:2,6|8,11|13,19|22,24|26,34|37,37|41,43|45,46|50,52|55,55|57,59|62,67 ??SSSSS?EEEE?SSEEEEE??SSS?EEEEEEESS??S???EEE?TT???EEE-?S?TTS??EEEEEE? 3AIT|A PF01357.16_Pollen_allerg_1_seed 136 134 !Q:0,0|5,5|8,9|20,23|26,26|35,55|58,80|83,83|85,86|90,90|93,94|97,99|102,105|107,108|114,115|118,118|121,121|123,123|128,128|133,133 Q:1,4|6,7|10,19|24,25|27,34|56,57|81,82|84,84|87,89|91,92|95,96|100,101|106,106|109,113|116,117|119,120|122,122|124,127|129,132 ?EEEE?TT?-BTTEEEEEEE????SS?EEEEEEEE---------------------TT------------?----?---??EE?B??TTT?EE--EE?--SS?-??S-?EEEEE--EE-SS-S?EEEE-EEEE? 1BMW|A PF01358.13_PARP_regulatory_seed 6 310 !Q:1,2|5,8|13,20|27,30|50,51|58,58|62,63|70,71|73,73|88,90|99,101|107,107|110,113|119,122|133,134|139,139|145,157|176,177|185,188|192,198|203,204|208,209|212,213|216,218|225,226|229,231|236,236|257,257|262,263|266,267|281,283|285,286|288,289|309,309 Q:0,0|3,4|9,12|21,26|31,49|52,57|59,61|64,69|72,72|74,87|91,98|102,106|108,109|114,118|123,132|135,138|140,144|158,175|178,184|189,191|199,202|205,207|210,211|214,215|219,224|227,228|232,235|237,256|258,261|264,265|268,280|284,284|287,287|290,308 E??SS?-??BGGG????????GGGGGS??-?SSTTHHHHHHHHHHHHHHH--HHHHTT?STT-?EEEEES??S?HHHHHHHHHHHTTT???EEEEEESS???GGGTT?TT----EEEEE????HHHHHHHHHH--HTTS?EEEEE????????-????HHHHHHHHHHHHHHHHHH??SEEEEEE????GGG?---???EEEE??EEE??TT??TT???EEEEEE??TT???EEEE?HHHHHHHHHHHHHHHHTGGG?EETT??SS??BHHHHHHHHHHTT???S--S??SSHHHHHHHHHHHHHHHHT? 4DCG|A PF01359.13_Transposase_1_seed 63 86 !Q:2,9|14,14|18,22|25,27|30,31|42,42|52,52|55,58|68,68|81,85 Q:0,1|10,13|15,17|23,24|28,29|32,41|43,51|53,54|59,67|69,80 ES?--?????EEEE?SSS????-EE???TT??EEEEEEEEES-SSEEEEEEE?SS????HHHHHHHHH-HHHHHHHHHSTT????? 3HOT|A PF01361.16_Tautomerase_seed 28 68 !Q:0,0|8,10|13,18|38,41|45,45|53,53|57,57 Q:1,7|11,12|19,37|42,44|46,52|54,56|58,67 ?EEEEEEE---TT?----?HHHHHHHHHHHHHHHHHHH??-?GGG?EEEEEEE?GGG?EETTEEHHHH 3N4D|A PF01363.16_FYVE_seed 174 304 !Q:0,4|6,6|9,11|13,13|16,17|19,21|23,39|41,50|52,55|57,60|63,63|67,88|91,130|135,160|164,164|167,229|234,238|242,291|294,294 Q:5,5|7,8|12,12|14,15|18,18|22,22|40,40|51,51|56,56|61,62|64,66|89,90|131,134|161,163|165,166|230,233|239,241|292,293|295,303 ?????G-GG?-?B?TT--T??-B?-?--------------S----------S----S??--EE?TTT??--------------------EE?---------------------------------------GGGS-------------------------?EEE-EE---------------------------------------------------------------TTTT-----EEE--------------------------------------------------EE?HHHHHHHHH 2YQM|A PF01364.13_Peptidase_C25_seed 77 932 !Q:4,7|9,11|15,31|46,51|53,53|64,64|67,90|94,118|132,133|136,138|140,146|152,152|154,188|192,193|196,310|322,323|326,372|376,377|379,380|387,388|408,409|412,412|414,428|434,435|440,440|442,543|550,551|568,568|576,610|614,615|625,625|627,630|636,637|639,639|641,647|649,649|654,661|665,685|693,695|698,704|715,715|721,737|745,747|754,754|756,756|764,772|774,810|828,828|831,832|836,847|849,862|877,882|887,911|926,926|929,929|931,931 Q:0,3|8,8|12,14|32,45|52,52|54,63|65,66|91,93|119,131|134,135|139,139|147,151|153,153|189,191|194,195|311,321|324,325|373,375|378,378|381,386|389,407|410,411|413,413|429,433|436,439|441,441|544,549|552,567|569,575|611,613|616,624|626,626|631,635|638,638|640,640|648,648|650,653|662,664|686,692|696,697|705,714|716,720|738,744|748,753|755,755|757,763|773,773|811,827|829,830|833,835|848,848|863,876|883,886|912,925|927,928|930,930 EEEE----E--?GGG-----------------TTTTHHHHHHHHHT------T?EEEEEEHHHH?SS?----------------------?HHH-------------------------HHHHHHHHHTSTT??EE---E-------EEEES?T-----------------------------------TTS??EE-------------------------------------------------------------------------------------------------------------------ETTEEESGGGG??SS-----------------------------------------------SSS??S--SEEEEE??SSHHHHHHHHHHHHHHHHT??TT?T---------------TTTEE--EEEE?S---------------------------------------------------------------------------------------------------???TTSGGG??HHHHHHHHHHHHHHHT?SEEEEEE-----------------------------------SSS??HHHHHHHHH-H--??SEEEE--E-S------?B?SSBB--------TTT?-------------?------BGGGGGG???TT----???EEEEESSSTT?TTSSS?---------------?HHHHHHH?--EETTEE?S?SEEEEES---------S??-----------------------------------BSSHHHHHHHHHHHHHT?SS??SGG------------G--------------BHHHHHHHHHHHHH------HHHT-------------------------HHHHHHHHHEEEES?TT?B? 4IEF|B PF01365.16_RYDR_ITPR_seed 18 248 !Q:17,18|21,24|26,28|34,37|62,82|87,102|119,119|132,139|146,146|162,247 Q:0,16|19,20|25,25|29,33|38,61|83,86|103,118|120,131|140,145|147,161 HHHHHHHHHHHHHTTTS??SS---?S---GGGGG????HHHHHHHHHTTHHHHHHHHHHGGG???--????????????????HHHH----------------HHHHHHHHHHHHHHTT?HHHHHHHHHHHH--------HHHHHH?TTHHHHHHHHHHHTT?-------------------------------------------------?-------------?--------------------- 4I6I|A PF01367.15_5_3_exonuc_seed 27 120 !Q:0,1|5,8|17,17|22,28|32,32|42,42|45,45|50,54|56,57|59,59|63,68|74,74|86,88|90,113 Q:2,4|9,16|18,21|29,31|33,41|43,44|46,49|55,55|58,58|60,62|69,73|75,85|89,89|114,119 ??GGG----HHHHHHTS?TTTS???????STT?TTTTTGGGG?SS?BTTB--???S??T-TTT------HHHHT?TTTHHHHGGGG???S?????????---------??????HHHHHH 1XO1|A PF01368.15_DHH_seed 150 451 !Q:5,5|8,8|12,13|15,16|36,37|42,307|313,338|342,342|345,369|372,372|379,393|410,424|426,438 Q:0,4|6,7|9,11|14,14|17,35|38,41|308,312|339,341|343,344|370,371|373,378|394,409|425,425|439,450 HHHTT?EE-EEE??S--SHHHHHHHHHHHHHHHHTT?-EEEE???????????---???????----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------???????EEEES??-???????????????-------?EEE-EE???????????------------??EE?GGGSTT---------??????HHHHHHHHHHHHHHHT---------------T-------??--??GGGHHHHHHHHH 1WPM|A PF01369.15_Sec7_seed 140 673 !Q:0,9|12,28|31,31|34,41|50,55|57,59|73,73|75,94|100,103|106,115|119,119|121,121|123,123|126,136|138,138|148,152|157,189|200,200|202,222|225,225|238,244|259,294|299,468|470,470|472,481|484,525|527,527|531,532|538,540|554,554|556,556|558,564|566,592|601,628|631,640|645,647|657,665|671,672 Q:10,11|29,30|32,33|42,49|56,56|60,72|74,74|95,99|104,105|116,118|120,120|122,122|124,125|137,137|139,147|153,156|190,199|201,201|223,224|226,237|245,258|295,298|469,469|471,471|482,483|526,526|528,530|533,537|541,553|555,555|557,557|565,565|593,600|629,630|641,644|648,656|666,670 ?--------?SH-----------------HH-HH--------HHHHHHHH------H?--HHHHHHHHHHTTS-S-------------------?SSHHH----HH----------HHH-H-H?TT-----------S?HHHHHHHHT?---?SHHH---------------------------------HHHHHHHHHT-S???------------------SS?HHHHHHHHHHSS???----SSHHHHHHHHHHHH------------------------------------HHHH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------H-T?---------TT----------------------------------------??S?SSH--HHHHH---HHHHHHHHHHHHT?T-T----??-S?------------------------??HHHHHHHT?---------------------------SS?---------SSSS-??HHHHHHHHH---------HHHHS?? 1R8M|E PF01370.16_Epimerase_seed 96 403 !Q:22,22|24,32|37,65|69,72|75,76|88,92|95,98|102,106|108,110|116,116|118,118|127,130|143,151|155,161|165,165|173,173|180,182|186,193|195,209|213,220|223,226|242,247|251,252|254,257|264,265|268,268|271,278|280,280|297,306|310,344|349,356|359,360|363,364|383,398|402,402 Q:0,21|23,23|33,36|66,68|73,74|77,87|93,94|99,101|107,107|111,115|117,117|119,126|131,142|152,154|162,164|166,172|174,179|183,185|194,194|210,212|221,222|227,241|248,250|253,253|258,263|266,267|269,270|279,279|281,296|307,309|345,348|357,358|361,362|365,382|399,401 EEEETTTSHHHHHHHHHHHHTT?E---------EEEE??????????????????----???????EEE????SS-?HHHHHHHHHHH---??SE----EEE?????T---TTTTT-S?HHHHHHHH----THHHHHHHHHHH---------HTT?------TTT?EEEEEEE-GGGGTT?-?SSS--------B--------------?TTS??---???SH----HHHHHHHHHHHHHHH------HHH--H-???EEEEEE??EE?TT--------S?TTSHHHHHHHHHHHHH----------TTS?--------------------------------??EEES-------?TT?-EE??EEHHHHHHHHHHTTSSSS-------------???EEE? 1DB3|A PF01371.14_Trp_repressor_seed 19 88 !Q:12,13|27,27|43,43|49,50|59,61|76,76 Q:0,11|14,26|28,42|44,48|51,58|62,75|77,87 HHHHHHHHHHHT??SHHHHHHHHHHHS?HHHHHHHHHHHHHHH-HHHHT??HHHHHHHH???HHHHHHHHHHHHSS?SHHHHHHHHTT 1JHG|A PF01372.12_Melittin_seed 3 26 !Q:0,1|19,25 Q:2,18 ??HHHHHHHHTHHHHHHHH??????? 2L36|A PF01373.12_Glyco_hydro_14_seed 5 434 !Q:3,4|7,13|16,18|32,33|46,46|52,54|69,69|77,77|79,79|82,82|86,86|88,88|91,91|93,93|101,101|104,104|110,110|113,114|117,117|120,127|135,136|155,155|158,159|164,165|173,177|182,184|187,194|222,224|229,230|232,233|235,235|237,237|283,284|290,294|299,299|312,312|314,320|333,333|338,339|342,349|353,357|374,375|380,380|383,385|389,390|403,403|406,410|415,415|421,421|425,425|427,427 Q:0,2|5,6|14,15|19,31|34,45|47,51|55,68|70,76|78,78|80,81|83,85|87,87|89,90|92,92|94,100|102,103|105,109|111,112|115,116|118,119|128,134|137,154|156,157|160,163|166,172|178,181|185,186|195,221|225,228|231,231|234,234|236,236|238,282|285,289|295,298|300,311|313,313|321,332|334,337|340,341|350,352|358,373|376,379|381,382|386,388|391,402|404,405|411,414|416,420|422,424|426,426|428,433 EEE??SS??---??HH---HHHHHHHHHHHTT??EEEEEEEHHHHS?SBTTB???HHHHHHHHHHHHTT?EEEEEEE?S?EE?STT?S?EE?S?GGGGGTS?HH-HHSEE?TT??EE?SS??------TTSHHHH--HHHHHHHHHHHHHHGGGG-GG??EEEE??SGGGSSS?????GGGT-??TT????????SHHHHHHHHHHHHHHHSSHHHHHHHHT???SSGG--G??S?S?STTTTTTSTTTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTT??EEEEE?????TTSS?SSSTTHHHHHHT?S?------HHHHHHHHHHHT?EEEE??TT????--??TTT??--?HHHHHHHHHHHHHHHT??EEEE?SS???THH--HHHHHHHHHHTT?SE-----EEES?GGGTB?TTS?B?TTHHHH 2XGI|A PF01374.13_Glyco_hydro_46_seed 7 228 !Q:10,10|12,12|19,19|22,23|28,29|38,39|46,46|50,50|62,62|65,66|76,77|88,88|90,90|104,104|132,134|149,149|165,167|170,177|190,191|201,202|208,209|223,223|226,226 Q:0,9|11,11|13,18|20,21|24,27|30,37|40,45|47,49|51,61|63,64|67,75|78,87|89,89|91,103|105,131|135,148|150,164|168,169|178,189|192,200|203,207|210,222|224,225|227,227 HHHHHHHHHS?S?GGGGGG?EE??SSSS??EETTTTEE??BTTBSS?SHH-HHHHHHHHHTT?SS??HHHHHHHTT??EEEETTEEEE?S?HHHHHHHHHGGGG?HHHHHHHHHHHHHHTHHHHHHHHHHTT???HHHHHHHHHHHHHH?SSSSTTSHHHHHHTS???SS--------HHHHHHHHHHHH--HHHHTSTTT??TTHHH--HHHHHHHHHHHTT?TT?S 1QGI|A PF01375.12_Enterotoxin_a_seed 6 272 !Q:0,22|31,31|42,43|46,48|51,52|55,59|66,72|74,75|99,99|109,110|123,123|125,125|127,127|131,132|138,138|152,155|160,160|162,164|167,167|170,171|178,182|190,193|196,196|208,210|219,223|249,253|261,262|267,271 Q:23,30|32,41|44,45|49,50|53,54|60,65|73,73|76,98|100,108|111,122|124,124|126,126|128,130|133,137|139,151|156,159|161,161|165,166|168,169|172,177|183,189|194,195|197,207|211,218|224,248|254,260|263,266 --------------------???EEEEEESS?HHHHHHHTEE??TT???SS??SS?????HHHHHH???????S??TTEEEEBSSHHHHHHHHHHHSTT?SEEEEEEEE??TTEEEHHHHHGG-G?S?GGG??EEEET?EEGGGEEEEEEEE----TTEE?S?-?EE?TT??HHHHHT?????GGGTGGG????TT?GGGGSTTGGGT-??TTSTTSTT?????HHHHHHHHHHHHHHHHHHHHHHHHH-----HHHTTTT??HHHH????? 1S5E|A PF01376.13_Enterotoxin_b_seed 5 102 !Q:0,1|22,23|30,30|34,36|41,41|45,45|50,58|79,80 Q:2,21|24,29|31,33|37,40|42,44|46,49|59,78|81,101 ??SSHHHHHHTSTTEEEEEEEE??SEEEEE?STT???EEEE?TTS?EEEE?????????HHHHHHHHHHHHHHHHHHTT??EEEEEEESSSSSEEEEEEEEE 1G8Z|D PF01378.12_IgG_binding_B_seed 4 56 !Q:7,7|10,10|27,27|38,40|55,55 Q:0,6|8,9|11,26|28,37|41,54 EEEEEEE?SS?EEEEEEEESSHHHHHH-HHHHHHHHTT???EEEEETTTTEEEEE? 3V3X|A PF01379.15_Porphobil_deam_seed 19 238 !Q:6,7|26,26|29,33|40,42|47,62|76,80|82,82|93,93|95,97|106,112|117,120|123,123|130,130|133,133|137,139|150,150|157,160|162,162|174,175|177,177|190,192|195,195|199,199|203,208|213,215|220,220|229,229 Q:0,5|8,25|27,28|34,39|43,46|63,75|81,81|83,92|94,94|98,105|113,116|121,122|124,129|131,132|134,136|140,149|151,156|161,161|163,173|176,176|178,189|193,194|196,198|200,202|209,212|216,219|221,228|230,237 EEEEEE??SHHHHHHHHHHHHHHHHH?TT----?EEEEEE???HHHH??????????---???TTTHHHHHHHHTT-----S?SEEEEEGGGS?S???TTEEEEEE???????EEEE?---SS?SSTTTS?TT?EEE???HHHHHHHHHH?TTSEEE?-??S?HHHHHHHHHTT--S?SEEEEEHHHHHH---TT?GGG?SEE----??TTTS???TTTT?EEEEEETT?HHHHHHHG 1PDA|A PF01380.17_SIS_seed 45 151 !Q:3,3|6,7|13,13|19,19|29,29|34,35|39,40|45,49|54,54|58,59|62,62|68,70|74,75|84,84|91,93|95,96|102,102|112,114|120,122|124,125|130,130|133,134 Q:0,2|4,5|8,12|14,18|20,28|30,33|36,38|41,44|50,53|55,57|60,61|63,67|71,73|76,83|85,90|94,94|97,101|103,111|115,119|123,123|126,129|131,132|135,150 HHT?SS-?EEEEE?HHHHH-HHHHHHHHH-HTTT??EEE??TTHH-----HHHT-STT??TT?EEEEE?--SSS??HHHHHHHH-HHHTTT-??E--EEEES?TTSHHHHHS---SEEEE???S??SSTT?SS??HHHHHHHHHHHHHHHH 3OOJ|A PF01381.17_HTH_3_seed 175 66 !Q:6,7|11,12|14,15|24,27|38,40|42,45|59,61 Q:0,5|8,10|13,13|16,23|28,37|41,41|46,58|62,65 HHHHHH--HHT??H--HHHHHHHT--??HHHHHHHHTT---S????BHHHHHHHHHHTT-??HHHH 3U3W|A PF01382.12_Avidin_seed 15 136 !Q:0,5|14,14|19,23|34,34|36,37|42,45|47,48|55,63|67,67|70,70|78,82|87,87|98,99|103,103|114,116|125,125 Q:6,13|15,18|24,33|35,35|38,41|46,46|49,54|64,66|68,69|71,77|83,86|88,97|100,102|104,113|117,124|126,135 ?--???EEEEETTS?EEEE???-?TTSEEEEEEE?S??SSSB????E--EEEEEE-------??GGG?SS?EEEEEEE?----SSSS?EEEEEEEEEE?-TTS?EEEEEEEEEE???SSGGGGGG?EEEEEEEEEE 1VWQ|B PF01383.16_CpcD_seed 86 63 !Q:0,3|11,13|16,19|21,22|24,27|36,36|54,54 Q:4,10|14,15|20,20|23,23|28,35|37,53|55,62 ?--?EEEEEEE???SS????S??H----HHHEEEEE-EEHHHHHHHHHHHHHTT?EEEEEEET 1B33|N PF01386.14_Ribosomal_L25p_seed 184 120 !Q:0,0|5,14|16,16|26,26|29,29|36,36|39,39|41,48|54,54|64,66|74,75|80,80|83,86|88,93|96,96|102,105|107,107|112,113|116,117 Q:1,4|15,15|17,25|27,28|30,35|37,38|40,40|49,53|55,63|67,73|76,79|81,82|87,87|94,95|97,101|106,106|108,111|114,115|118,119 ?EEEE??----?--?S-HHHHHHHHT-SS?EEEEEE?TT-S?-?-----EEEEE?HHHHHHHHH---SGGGGTS?-EEEE-ET----T------EE-EEEEE????B?SSSS-?BS??EE 2ZJQ|S PF01387.12_Synuclein_seed 4 148 !Q:0,1|24,34|49,50|54,54|104,108|110,115|117,121|126,126|128,133|144,144|147,147 Q:2,23|35,48|51,53|55,103|109,109|116,116|122,125|127,127|134,143|145,146 ??HHHHHHHHHHHHHHHHHHHHHH-----------HHHHHHHHHHHHHS??TTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS?????S???--?S?????SSSS?S?---??BTTTBTTTSS?TT? 3Q28|A PF01388.16_ARID_seed 53 150 !Q:2,3|22,35|38,39|41,56|62,63|76,76|79,84|91,99|108,109|111,112|114,118|124,133 Q:0,1|4,21|36,37|40,40|57,61|64,75|77,78|85,90|100,107|110,110|113,113|119,123|134,149 TT??HHHHHHHHHHHHHHHHTT??----------?-SS??E----------------ETTEE??HHHHHHHHHHHT?HH------HHHHHT?--------HHHHHHHT--T??T-----TSTTH----------HHHHHHHHHHHSSHHH 1KN5|A PF01389.12_OmpA_membrane_seed 13 242 !Q:0,1|15,46|62,65|78,114|151,151|155,167|200,227|237,241 Q:2,14|47,61|66,77|115,150|152,154|168,199|228,236 ??TTEEEEEEEEEEE??????---------------???????????EEEEEEEEEEEEETT----EEEEEEEEEEEE????????--------------------------???EEEEEEEEEEEEEEESSSSEEEEEEEEEEEEEEEEE?SSS?------------EEEEEEEEEEEEEEEEEEEETTEEEEEEEEEE???????????------------?????EEEEEEEEE????? 1G90|A PF01390.15_SEA_seed 94 159 !Q:0,1|12,12|17,23|28,28|46,48|59,61|73,97|101,106|110,112|122,122|124,129|144,146|148,148|156,156 Q:2,11|13,16|24,27|29,45|49,58|62,72|98,100|107,109|113,121|123,123|130,143|147,147|149,155|157,158 ??EEEEEEEEEE-EEEE-----??GGGG?TTSHHHHHHHHHHHHHH---HHHHHTSTTT---TTEEEEEEEEE-------------------------EEE------TTE---EEEEEEEEE-E??????HHHHHHHHHHHHGG---G?SSSSSEE?SS 2E7V|A PF01391.13_Collagen_seed 41 60 !Q:0,59 Q: ???????????????????????????????????????????????????????????? 1WZB|A PF01392.17_Fz_seed 26 150 !Q:0,0|3,7|15,15|19,19|22,22|25,26|29,30|38,42|53,58|61,61|74,74|76,78|81,82|84,89|91,91|101,101|110,120|123,126|130,130|135,136|139,143|147,148 Q:1,2|8,14|16,18|20,21|23,24|27,28|31,37|43,52|59,60|62,73|75,75|79,80|83,83|90,90|92,100|102,109|121,122|127,129|131,134|137,138|144,146|149,149 ?EE??--?GGGTTSS?SEE?SS?TT??SS--HHHHHHH-----HGGGHHHHHH------TS?TTHHHHHHHHHS?B?-?SS??S?---??B?HHHHHHHHH-HHHHHHHT-----------TT????GGG?STTS??SS?----SSS??B 1IJY|A PF01393.14_Chromo_shadow_seed 8 63 !Q:2,2|17,17|21,21|31,31|33,33|57,62 Q:0,1|3,16|18,20|22,30|32,32|34,56 TT?TTTTTEEEEEEEEE?TTS?EEEEEEETT-S?EEEEEHHHHHHHSHHHHHHHHHT?????? 2FMM|A PF01394.15_Clathrin_propel_seed 71 44 !Q:7,8|11,11|14,14|24,30|42,42 Q:0,6|9,10|12,13|15,23|31,41|43,43 EEEEEEE??TT?SS?EEEEEEEEE-------ETTEEEEEEEE?S 1C9L|A PF01395.17_PBP_GOBP_seed 158 189 !Q:0,7|10,14|17,17|19,19|27,35|46,48|50,53|55,55|65,78|91,91|93,94|97,97|99,103|107,107|109,113|122,122|127,135|142,146|150,158|160,162|165,166|174,174|178,181|187,187 Q:8,9|15,16|18,18|20,26|36,45|49,49|54,54|56,64|79,90|92,92|95,96|98,98|104,106|108,108|114,121|123,126|136,141|147,149|159,159|163,164|167,173|175,177|182,186|188,188 ?????--?SS-----SS-S?HHHHHHH---------HHHHHHHHHH---H-???H-HHHHHHHHS?????---------HHHHHHHHHHHH-H--TT?B?----TTS?B--?--HHHHHHHS?GGGH---------HHHHHH-----HTT??-------S???SS--HHHHHHH-HHH----HHHHH?T 3FE6|A PF01397.16_Terpene_synth_seed 141 249 !Q:5,5|7,21|23,33|44,44|49,49|52,52|55,55|58,60|62,66|83,83|87,87|93,93|103,106|109,125|141,144|147,147|153,153|155,155|160,161|163,163|165,165|169,170|172,172|174,174|185,185|188,189|192,194|196,196|204,204|216,217|219,220|222,223|225,237|239,240 Q:0,4|6,6|22,22|34,43|45,48|50,51|53,54|56,57|61,61|67,82|84,86|88,92|94,102|107,108|126,140|145,146|148,152|154,154|156,159|162,162|164,164|166,168|171,171|173,173|175,184|186,187|190,191|195,195|197,203|205,215|218,218|221,221|224,224|238,238|241,248 TTTTT-T---------------S???----????HHHHHHHHHH-HHHH-HH-HH-HS-??S-----SHHHHHHHHHHHHHTT?GGG?HHHHH-HHHHHHHHS-???TT---?------------?HHHHHHHHHHHHHTT????GG-GGGGG-B?TTSS--B?H-HHH--H?H-HHHHHHHHHH-TT??TT?--H-HHHHHHH-HHHHHHHHHST--T??T--T-------------H--HHHHHHHH 3LZ9|A PF01398.16_JAB_seed 30 196 !Q:0,0|2,2|8,8|27,49|51,52|64,88|99,99|103,103|106,106|113,113|129,158|161,162|170,171|174,179|193,193|196,196 Q:1,1|3,7|9,26|50,50|53,63|89,98|100,102|104,105|107,112|114,128|159,160|163,169|172,173|180,192|194,195 ?S?SEEEE?HHHHHHHHHHHHHHHHTT?---------------------?S??EEEEEEEESSS-------------------------EEEEEEEEEE?EEE?SS?TTSEEE?HHHHHHHHHHHHTTS------------------------------SS-?EEEEEEE??SS?----?TTHHHHHHHHTTT?TT- 4F7O|A PF01399.22_PCI_seed 77 181 !Q:13,14|26,57|66,66|70,80|106,108|124,126|132,136|142,143|146,146|160,162|169,172|179,180 Q:0,12|15,25|58,65|67,69|81,105|109,123|127,131|137,141|144,145|147,159|163,168|173,178 HHHHHHHHHHHHT?-HHHHHHHHHHT--------------------------------HHHHHHTT?HHH-----------HHHHHHHHHHHHHHHHHHHHHTTTT???EEEHHHHHHHHHHHH???TTSTT?????TTTSS??SS?HHHHHHHHHHHTS??-EEEETT----TTEEEE?? 3CHM|A PF01400.19_Astacin_seed 26 211 !Q:2,2|6,10|17,17|20,21|41,41|46,46|49,55|58,58|64,72|75,78|81,82|88,89|93,94|110,111|125,125|130,130|133,133|138,141|146,147|150,153|156,156|159,161|172,172|178,191|194,195|208,210 Q:0,1|3,5|11,16|18,19|22,40|42,45|47,48|56,57|59,63|73,74|79,80|83,87|90,92|95,109|112,124|126,129|131,132|134,137|142,145|148,149|154,155|157,158|162,171|173,177|192,193|196,207 GS?GGG-----EEEEEE?SS??HHHHHHHHHHHHHHHHHSS?EEEE?SS?------SS?EEEEE??????-??SS??-?SS?-EEEEE?-TTS?-SHHHHHHHHHHHHTB??GGGSTTGGGTEEE?GGGB?TT?GGGG????GGGB??TT????TT?TT???TTTTBSSTTS?SEEES????-?????????SS??HHHHHHHHHHTT??? 1IAC|A PF01401.13_Peptidase_M2_seed 6 600 !Q:0,0|5,9|44,45|81,81|83,83|95,96|102,102|123,123|126,127|130,134|148,150|189,189|201,202|236,236|240,241|245,245|256,256|258,259|267,267|270,270|273,274|276,276|286,287|304,308|315,315|317,317|319,320|324,328|330,330|335,335|340,340|345,348|350,350|374,374|378,378|380,380|409,414|453,453|470,470|473,473|476,478|481,482|494,496|519,520|522,522|526,528|531,531|549,549|560,560|563,564|588,589|592,592|597,599 Q:1,4|10,43|46,80|82,82|84,94|97,101|103,122|124,125|128,129|135,147|151,188|190,200|203,235|237,239|242,244|246,255|257,257|260,266|268,269|271,272|275,275|277,285|288,303|309,314|316,316|318,318|321,323|329,329|331,334|336,339|341,344|349,349|351,373|375,377|379,379|381,408|415,452|454,469|471,472|474,475|479,480|483,493|497,518|521,521|523,525|529,530|532,548|550,559|561,562|565,587|590,591|593,596 ?GGGS?????SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTS?S?HHHHHHHHHHS??GGGGS?HHHHHHHHHHHHHHHHHHHH?EE??SS?????EETTTHHHHHHHH???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT?SSHHHHHHGGG??TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?TTT??TTS?EETTSSSSTT?S??GGGHHHH?SS?SS??S?THHHHHHHT??HHHHHHHHHHHHHHTT?????HHHHHH?B?S??SSS?????S?EEEE?SSSS?EEEE????S?HHHHHHHHHHHHHHHHHHHHTTS?GGG?S?SSHHHHHHHHHHHHHHHHSHHHHHHTTS??????SHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHTSS?GGGHHHHHHHHHHHHH?EE?SS???TT??GGGGSTTTTTT???HHHHHHHHHHHHHHHHHHHHHT??S?GGG???TT?HHHHHHHHHHHTTTTSS?HHHHHHHHHS?SS??SHHHHHHSHHHHHHHHHHHHHTT??SS?SSTT??? 1O8A|A PF01402.16_RHH_1_seed 49 40 !Q:22,24|39,39 Q:0,21|25,38 EEEEEEEHHHHHHHHHHHHHHT-??HHHHHHHHHHHHTT? 2WVC|A PF01403.14_Sema_seed 26 561 !Q:1,1|16,16|27,27|30,33|36,38|43,49|61,62|64,68|74,74|86,86|93,94|98,98|104,105|107,108|112,142|144,147|150,151|153,154|157,157|162,162|168,169|175,175|177,181|184,189|196,196|198,203|207,208|216,224|227,228|231,232|235,238|242,242|245,245|254,255|260,264|267,267|277,291|303,306|312,312|315,315|318,318|324,325|328,329|333,336|339,340|349,350|352,352|354,362|364,365|373,373|375,375|379,384|400,400|403,403|407,410|416,417|420,421|423,426|429,429|432,435|440,444|450,450|460,461|466,466|468,469|474,474|479,479|483,484|492,493|497,497|500,500|502,502|517,517|523,530|540,540|544,552 Q:0,0|2,15|17,26|28,29|34,35|39,42|50,60|63,63|69,73|75,85|87,92|95,97|99,103|106,106|109,111|143,143|148,149|152,152|155,156|158,161|163,167|170,174|176,176|182,183|190,195|197,197|204,206|209,215|225,226|229,230|233,234|239,241|243,244|246,253|256,259|265,266|268,276|292,302|307,311|313,314|316,317|319,323|326,327|330,332|337,338|341,348|351,351|353,353|363,363|366,372|374,374|376,378|385,399|401,402|404,406|411,415|418,419|422,422|427,428|430,431|436,439|445,449|451,459|462,465|467,467|470,473|475,478|480,482|485,491|494,496|498,499|501,501|503,516|518,522|531,539|541,543|553,560 B?EEEEETTTTEEEEE?BSEEEEEETT?TT----SE---EEEE????---HHHHHHHHHTT??T-----TTTSS?BEEEEEEEETT-EEEEEE??SSS?EEEEE--E??SSS-------------------------------S????EE??S??EE?TTTS?SSSSS??EEEEE-T-----TE------EEEEEE?S------TTS??EEEEEES?--------SS??EE??SS---?TTT?SS?EEEEEEEE??SSST-----TS?EEEEEEEEE?????-??----???EEEEEEEEETT????SSSST-TB?SS?EEEEE??EE??TTS??--EE??EEEEEEEE??S?T---------T??EEEEEEE?S?SSS??----EEEEEEEHHHHHHHH-HS?BEE?---SSTTB??EE??S-???SS?TT????SSSS??--?SSTTS?HHHHHTTTS??BBSS?B??GGGS?SEEE?SSS??EEEEEEE--EEE?SS?E-EEEEEEEETTSEEE-EEEEE????????EEEEEEEEE?SSS?----????EEEEETTT 3AFC|A PF01404.14_Ephrin_lbd_seed 33 229 !Q:5,5|12,16|25,34|37,40|42,42|47,50|55,62|67,68|73,75|78,79|82,82|84,84|93,95|102,102|105,106|111,111|120,133|136,139|141,143|147,147|154,156|158,175|179,185|192,200|202,202|226,227 Q:0,4|6,11|17,24|35,36|41,41|43,46|51,54|63,66|69,72|76,77|80,81|83,83|85,92|96,101|103,104|107,110|112,119|134,135|140,140|144,146|148,153|157,157|176,178|186,191|201,201|203,225|228,228 SEEEE?TTTSSS??-??EEESSTTS---------?EE????B-TTTB????EEEE--??----SSSS??EEEE???EE?-SS?S?EEEEEEEE???TTTSSS?TT--TSBS?EEEEEEEE??------------SS?---S???SSS?EEEEEE???S?-?????-----------SSS??-????EEEEEE??-----??S-SEEEEEEEESSBEEEEEEEEEEE??B 3HPN|A PF01405.12_PsbT_seed 3 29 !Q:0,0|24,28 Q:1,23 ?HHHHHHHHHHHHHHHHHHHHHSS????? 3PRR|T PF01406.14_tRNA-synt_1e_seed 11 437 !Q:1,3|14,16|21,22|43,43|46,46|53,53|56,57|70,185|206,209|212,213|218,218|238,238|241,245|247,247|251,251|255,255|264,288|292,292|299,300|304,309|311,312|315,315|320,320|334,339|347,347|369,369|371,372|377,378|380,381|388,390|395,397|407,407|419,419|423,423|427,427 Q:0,0|4,13|17,20|23,42|44,45|47,52|54,55|58,69|186,205|210,211|214,217|219,237|239,240|246,246|248,250|252,254|256,263|289,291|293,298|301,303|310,310|313,314|316,319|321,333|340,346|348,368|370,370|373,376|379,379|382,387|391,394|398,406|408,418|420,422|424,426|428,436 E???SSTTEEEEEE???BSSS??BHHHHHHHHHHHHHHHHHHH-HT?EEEEEE?BB??SHHHHHHHHHTT??------------------------------------------------------------------------------------------------------------------HHHHHHHHHHHHHHHHHHTT????SB??BGGG?HHHHHHHHHHHHHTTSEEE?TT-----S?EEE?GGG?TTTTTTTT???????????????------????STT?EEEEEE??TTS----??B??TT?SEEE?SSHHHHHHHHHHH?-----SSEEEEE?BGGGTTTHHHHHHHHHHHHSS-S??EEEE??B??EEETTB???GGGT???BHHHHHTTS?HHHHHHHHHSS?TTS?EEE?HHHHHHHHH 1LI5|A PF01408.17_GFO_IDH_MocA_seed 52 188 !Q:6,8|12,14|19,21|29,29|33,39|46,46|48,48|56,59|65,66|72,72|76,85|88,88|93,93|95,96|98,102|107,107|109,109|111,116|119,122|135,137|142,142|146,146|148,153|170,182|186,187 Q:0,5|9,11|15,18|22,28|30,32|40,45|47,47|49,55|60,64|67,71|73,75|86,87|89,92|94,94|97,97|103,106|108,108|110,110|117,118|123,134|138,141|143,145|147,147|154,169|183,185 EEEEEE??-SHH---HHHT---HHHHGGG?SSE-------EEEEEE?S?HHHHHHH----HHHHT??GGGEE?SSS----------GG-GGGG?T--T---??EEEE?S?T------TH----HHHHHHHHHHTT?--EEEE?SSS?S------SHHHHHHHHHHHHHHT----------??-EEE?? 3FHL|A PF01409.15_tRNA-synt_2d_seed 46 323 !Q:0,2|6,19|37,37|40,44|58,59|62,62|66,66|71,71|74,77|79,114|116,116|121,121|133,137|142,142|144,146|157,158|160,162|167,167|181,182|184,185|202,202|205,207|227,251|261,261|269,275|277,278|280,281|284,284|292,292|303,305|312,315 Q:3,5|20,36|38,39|45,57|60,61|63,65|67,70|72,73|78,78|115,115|117,120|122,132|138,141|143,143|147,156|159,159|163,166|168,180|183,183|186,201|203,204|208,226|252,260|262,268|276,276|279,279|282,283|285,291|293,302|306,311|316,322 ???TTS?---??????????HHHHHHHHHHHHHHTTT?EE??-??SEEEHHHHTGGGT??TT?GGG?TTTS?BS----S------------------------------------S-SEEE?SSSHHHHHHHH-----HHHT-T???EEEEEEEEEE??S?-?BTTB?SEEEEEEEEEEET--T??HHHHHHHHHHHHHHHH?TT-??EEEEEEEETTEEEEEEEEE???????-------???????????EEEEEEEEE?HHHHHHT-------T??T--TT?EEEEEEE?HHHHHHHHHT???TTHHHH?--?HHHHGGG 2ZCE|A PF01410.13_COLFI_seed 36 254 !Q:0,4|6,6|11,11|14,14|22,22|25,30|37,37|40,40|45,45|47,47|53,54|59,60|66,66|70,72|78,92|100,120|123,123|127,127|132,134|145,145|147,147|159,160|163,163|168,168|171,171|174,175|179,179|183,183|190,190|195,195|199,199|202,203|206,207|218,219|223,223|227,227|229,230|234,234|237,238|242,242 Q:5,5|7,10|12,13|15,21|23,24|31,36|38,39|41,44|46,46|48,52|55,58|61,65|67,69|73,77|93,99|121,122|124,126|128,131|135,144|146,146|148,158|161,162|164,167|169,170|172,173|176,178|180,182|184,189|191,194|196,198|200,201|204,205|208,217|220,222|224,226|228,228|231,233|235,236|239,241|243,253 ?????S-SSSS?BS?HHHHHHH?TT----??SEEEEE?TT?SSGG-G?EEEEE--ETTT--TEEEE?BSS--?EEEEE???????-???????HHHHSTT??----------------???BS?TTS?HHHH---HHHHHHHHHH?S?EEEEEEEEEES??SS?BTTT-TB?TT??EEE?SSS?EEBSSS?TTSB?EEE-EE??SS??SSEEEEEEEE--EES?GGG?S??EEE?SS??STT?EEEEEEEEEEE 4AE2|A PF01411.14_tRNA-synt_2c_seed 25 677 !Q:11,11|13,13|17,18|21,25|28,28|30,30|32,32|35,35|38,39|54,57|59,60|73,74|76,79|90,91|104,104|107,111|125,126|129,133|135,137|146,147|152,157|162,162|179,188|193,197|199,200|203,204|206,207|239,240|243,245|264,275|289,290|296,296|311,311|322,339|361,363|384,384|389,394|410,410|454,454|456,458|470,472|485,490|503,523|531,539|542,542|547,570|573,575|584,584|590,597|601,601|605,605|607,608|614,617|619,621|628,631|644,644|653,655|657,657|660,663|666,666|673,673 Q:0,10|12,12|14,16|19,20|26,27|29,29|31,31|33,34|36,37|40,53|58,58|61,72|75,75|80,89|92,103|105,106|112,124|127,128|134,134|138,145|148,151|158,161|163,178|189,192|198,198|201,202|205,205|208,238|241,242|246,263|276,288|291,295|297,310|312,321|340,360|364,383|385,388|395,409|411,453|455,455|459,469|473,484|491,502|524,530|540,541|543,546|571,572|576,583|585,589|598,600|602,604|606,606|609,613|618,618|622,627|632,643|645,652|656,656|658,659|664,665|667,672|674,676 HHHHHHHHHHH-T?SSS??EE?????SS?T-T?SS?SS??SGGGGGTTHHHHTS----S??SSSSEEEEEEEE??T----TGGGTTTSSS??SEEEEEEEEEEE?TT?????HHHHHHHHHHHHH--HT-----S???GGGEEEEE??EEET------TEEE?EEEEEETTEEEEEEEE----------EEEE-----E??TT??S??EEETTTEEEEEEEEEEEEEEEEHHHHHHHHH??SS---HHHHHSHHHHHHHHHHHT???-------??HHHHHHHHHHHHT??SSSSS?HHHHHHHHHHHHTS?HHHHHHHHHH------------------HHHHHHHHHHHHHHHHHHHTT???SSSHHHHHHHHHHHHHHHHH-HHTT????--HHHHHHHHHHHHTTT?THHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS?S???HHHHHHHHHHH???HHHHHHHHTTSS??????TTHHHHHHGGGG???--???????-------??SSSSSSS???------EE-HHHH?-----------------------TT-??EEEEEEEE-EETTE--------EEE-SEE?S??SBTTB????E---EEEETT----EEEEEEEEEEET-TEEEEEES?--G-GG--??TT?EEEEEE?HHH 3HY0|A PF01412.13_ArfGap_seed 141 181 !Q:9,11|13,13|17,17|20,20|24,30|33,35|41,41|44,48|52,52|59,61|65,65|67,69|71,77|80,81|89,95|105,106|110,110|120,126|129,154|164,164|171,171|173,173|175,178 Q:0,8|12,12|14,16|18,19|21,23|31,32|36,40|42,43|49,51|53,58|62,64|66,66|70,70|78,79|82,88|96,104|107,109|111,119|127,128|155,163|165,170|172,172|174,174|179,180 HHHHHHHTT---S-GGG-GB?TTT---?--?BS?-?EEETT-TT-----EEE?HHHHHH---HHH-H?--T-------TT??EEETTTS--?--??HHHHHHHHT?-HHH-HHHHHHTTT?----?-SS-----????----------------?SHHHHHHHH-HHHHTS?T-T?--?TT 2CRR|A PF01413.14_C4_seed 26 118 !Q:1,1|7,7|12,16|33,33|37,37|41,42|53,54|57,57|70,71|73,73|75,75|82,84|90,91|93,95|102,102|109,109|117,117 Q:0,0|2,6|8,11|17,32|34,36|38,40|43,52|55,56|58,69|72,72|74,74|76,81|85,89|92,92|96,101|103,108|110,116 S?EEEEE?SSSS?????TTEEEEEEEEEEEEEE?STT?EEE??TTSGGGEESS??SS?EEEEETTTTEEE??T-T?EEEEEB??-SSSSB??S???EEEETT-SSGGGB?EEEEEEE? 1T61|A PF01414.14_DSL_seed 18 67 !Q:0,25|34,34|37,39|50,50|53,54|58,58 Q:26,33|35,36|40,49|51,52|55,57|59,66 -??????????----???????????TTEETTTT?EE???EEETTEEEEE?SS??EEE?TTEESTTS 2VJ2|A PF01415.11_IL7_seed 7 152 !Q:0,8|20,21|32,33|37,41|48,51|54,55|70,71|74,76|98,130|150,151 Q:9,19|22,31|34,36|42,47|52,53|56,69|72,73|77,97|131,149 ????---??SHHHHHTHHHH--HHHHHHHTTT??TTT?????HHHHHS?-??SS??HHHHHHHHHHHGGG??SS???HHHHHHHHHHHHHHHHHHTTS?????????????????????????????????HHHHHHHHHHHHHHHHHHH?? 3DI3|A PF01416.15_PseudoU_synth_1_seed 118 250 !Q:14,23|26,45|47,48|50,56|69,99|105,121|130,132|141,147|154,154|160,160|166,169|172,216|220,221|226,237|248,249 Q:0,13|24,25|46,46|49,49|57,68|100,104|122,129|133,140|148,153|155,159|161,165|170,171|217,219|222,225|238,247 HHHHHSEEEEGGGG?---------SS------------------??S??E-------EEEEEEEEEEEE?------------------------------SSSEE-----------------EEEEEEES???TTHHHHHH-------HHHHHH-HHSSS?GGGHH----HH---------------------------------------------HHH??GGGS??-------???GGGEEEEEEE?? 4ITS|A PF01417.15_ENTH_seed 72 219 !Q:0,2|12,15|17,23|25,25|38,38|53,109|111,115|118,118|125,133|146,146|148,152|159,159|170,170|173,178|180,180|182,186|189,200|215,216|218,218 Q:3,11|16,16|24,24|26,37|39,52|110,110|116,117|119,124|134,145|147,147|153,158|160,169|171,172|179,179|181,181|187,188|201,214|217,217 ???HHHHHHHHS???-S?-??--?S?HHHHHHHHHTSS-HHHHHHHHHHHHGG---------------------------------------------------------G---??SS?THHHHH---------HHHHHHHHHHTT?H-----HHHHHH-HHTHHHHHHH-HH???-??S-S?????HH------------HHHHHHHHHHHHTS??S? 1HX8|A PF01418.12_HTH_6_seed 10 77 !Q:0,1|14,14|27,27|34,35|45,46|59,59 Q:2,13|15,26|28,33|36,44|47,58|60,76 ??HHHHHHHHGGGS?HHHHHHHHHHHH?HHHHHT??HHHHHHHTT??HHHHHHHHHHTT?SSHHHHHHHHHHHHHSG 3IWF|A PF01419.12_Jacalin_seed 52 167 !Q:1,1|3,11|13,14|22,22|28,36|43,44|47,48|50,54|56,58|60,64|66,67|71,73|76,76|78,81|90,90|94,98|100,100|109,110|114,118|121,128|136,137|142,144|151,151|153,155|163,163 Q:0,0|2,2|12,12|15,21|23,27|37,42|45,46|49,49|55,55|59,59|65,65|68,70|74,75|77,77|82,89|91,93|99,99|101,108|111,113|119,120|129,135|138,141|145,150|152,152|156,162|164,166 S?B????---??S??SEEEEEE?SSSEE---------EEEEEB??TT??B?????S???T-----T??EEE???TT-T????EEEEEEEE?SSS-----S?EEEEEEEE??SSS-????EE-----???SEEEEEE?-SSEE???EEEEES-S---SEEEEEE?BEE 1J4S|A PF01420.14_Methylase_S_seed 65 263 !Q:3,3|5,5|16,19|22,26|29,29|36,37|39,49|53,53|63,63|67,69|74,74|83,85|87,88|91,91|96,96|98,105|107,110|114,114|121,130|132,133|136,136|138,139|148,148|152,156|166,169|174,179|185,191|193,193|198,201|207,208|210,210|215,223|225,225|228,233|247,247|254,254 Q:0,2|4,4|6,15|20,21|27,28|30,35|38,38|50,52|54,62|64,66|70,73|75,82|86,86|89,90|92,95|97,97|106,106|111,113|115,120|131,131|134,135|137,137|140,147|149,151|157,165|170,173|180,184|192,192|194,197|202,206|209,209|211,214|224,224|226,227|234,246|248,253|255,262 ETT?E-EEEHHHHEEE----EE?????TT?GGGTTT??E-----------EEE?HHHHHTTTT?SEE???SSEE?HHHHHHTT???B?-TT?EEEE?S--------S----STT?EEEESS----?-----B--EE?T--TEEEEEES?TTS??---HHHHHHHHH----HTHH------HHHHH-------H?SSSS????HHHHH--H?EEEE?-------?H-HH------HHHHHHHHHHHHH-HHHHHH-HHHHHHHH 1YF2|A PF01421.14_Reprolysin_seed 38 209 !Q:9,9|19,19|41,41|54,54|57,58|61,63|85,87|95,95|97,98|102,102|107,107|110,110|113,113|123,126|128,128|146,150|152,156|158,159|161,164|168,169|175,176|179,180|182,185|200,201|205,205|207,208 Q:0,8|10,18|20,40|42,53|55,56|59,60|64,84|88,94|96,96|99,101|103,106|108,109|111,112|114,122|127,127|129,145|151,151|157,157|160,160|165,167|170,174|177,178|181,181|186,199|202,204|206,206 EEEEEEEEE?HHHHHHTTT?HHHHHHHHHHHHHHHHHHHGG-GTEEEEEEEEEE?SS??SS???SSHHHHHHHHHHHHHHTTTTT???SEEEEEE?S??SSS?SEEE?TT?TT?TTTSEEEEE???-S?HHHHHHHHHHHHHHHTT?????T-----T??S----SSS??TTSSS??SS??S-???HHHHHHHHHHHHHH??GGG?S?? 1BKC|A PF01423.17_LSM_seed 129 119 !Q:7,13|24,25|27,27|38,38|41,42|52,52|56,93|98,101|104,104|108,108|117,117 Q:0,6|14,23|26,26|28,37|39,40|43,51|53,55|94,97|102,103|105,107|109,116|118,118 HHHHHHT-------TSEEEEEETT--T-EEEEEEEEEE?TT??EEEEEEEEE?SSS-------------------------------------?EEEE----EE-EEE?GGGEEEEE-E 2Y9B|A PF01424.17_R3H_seed 402 118 !Q:16,19|21,28|31,34|36,45|48,56|62,62|66,66|71,73|75,75|77,81|83,85|91,92|94,100|102,102|105,105|108,110|117,117 Q:0,15|20,20|29,30|35,35|46,47|57,61|63,65|67,70|74,74|76,76|82,82|86,90|93,93|101,101|103,104|106,107|111,116 HHHHHHHHHHHHHHHH----H--------HH?---S---------?EE??-?--?-?HHHHH-HHH-HHTT---T?S-----S---EEEEE--E-------S-ST-TS--?EEEEEE? 2LRR|A PF01425.16_Amidase_seed 44 587 !Q:17,18|23,23|34,36|40,48|53,53|62,63|65,65|69,70|73,73|78,79|81,81|83,83|86,89|100,100|107,108|113,114|120,120|123,135|143,148|184,184|189,196|201,202|206,212|214,214|218,218|238,238|240,241|244,244|248,262|269,271|274,274|284,321|324,327|346,347|353,354|363,363|380,380|387,392|394,395|407,408|410,411|415,415|438,438|448,448|461,476|484,484|488,489|496,507|521,523|531,532|536,541|548,548|550,567|578,578|581,581 Q:0,16|19,22|24,33|37,39|49,52|54,61|64,64|66,68|71,72|74,77|80,80|82,82|84,85|90,99|101,106|109,112|115,119|121,122|136,142|149,183|185,188|197,200|203,205|213,213|215,217|219,237|239,239|242,243|245,247|263,268|272,273|275,283|322,323|328,345|348,352|355,362|364,379|381,386|393,393|396,406|409,409|412,414|416,437|439,447|449,460|477,483|485,487|490,495|508,520|524,530|533,535|542,547|549,549|568,577|579,580|582,586 HHHHHHHHHHHHHHHHH??EEEE?HHHHHHHHHT???TTS---------TTTT?EEEEETTB??T-TSB??TT?GGGT--T?B?SS--??HHHHHHHHTT?EEEEEE??SGGG??SSSTT?SS---------????BTTBTTB---???SSSHHHHHHHHTTSSSSEEEEESSSTTHHHHHHHT?EEEE------??TTSS??TTB?-----?S?TTT?EEEEEESSHHHHHHHHHHT?S??TT?TTS??--------?????GGGTTT???TT?EEEEEGGGG--------------------------------------GS-???HHHHHHHHHHHHHHHHTT-?EEEEE??TTGGGHHH-HHHHHHHHHHHHHTTT?SSSSSS---???S??SSHHHHHHHHH--H--HHS?HHHHHHHHHHHHHTSTTTTTTT-HHHHHHHHH-HHHHHHHHHHHH---------------?SEEEEES?SSS??BTTTTS------------SSHHHHHGGGTTT---HHHHHHT??EEE------EEEEEE-T------------------TEEEEEEEEE?TT?HHHHH 1OBI|A PF01426.13_BAH_seed 41 349 !Q:0,3|6,6|11,12|15,49|53,59|68,202|205,205|208,216|221,222|227,236|238,238|243,247|250,250|255,261|263,264|272,274|303,322|328,330|339,339|347,347 Q:4,5|7,10|13,14|50,52|60,67|203,204|206,207|217,220|223,226|237,237|239,242|248,249|251,254|262,262|265,271|275,302|323,327|331,338|340,346|348,348 ????TT?EEEE??SS-----------------------------------TTS?-----?EEEEEEEE---------------------------------------------------------------------------------------------------------------------------------------EE?TT??-------EEEE--EEEE----------E?GGGS?--??TT?EEET-------T--EEEEEEE---EEEEEGGGEEEEEEEEEHHHHTTEEETT------------------??GGGEE---EEEEEEET-TTTEEEE?S 1W4S|A PF01427.12_Peptidase_M15_seed 5 217 !Q:0,1|14,14|17,18|24,24|30,31|35,35|39,39|68,71|85,88|95,95|99,99|110,110|113,113|119,119|131,132|134,136|139,139|142,143|151,151|154,154|156,156|165,174|188,188|191,191|200,200|202,206|209,214|216,216 Q:2,13|15,16|19,23|25,29|32,34|36,38|40,67|72,84|89,94|96,98|100,109|111,112|114,118|120,130|133,133|137,138|140,141|144,150|152,153|155,155|157,164|175,187|189,190|192,199|201,201|207,208|215,215 ??TTEEEGGGTSTT?EE??GGGSS?STTSS??TTB?SSS?EEEHHHHHHHHHHHHHTTSSSEEEEEEE????HHHHHHHHHHHTS????SSHHHH?SSS?TTHHHHTSSS?SS?GGGGT?EEEEEEEETTT??B???SS?TT??SGGGSTT?SS-S?HHHHHHHH----------HHHHHHHTTTEEE?TT?TTEEEESS?S----?TT??????B? 1R44|A PF01428.11_zf-AN1_seed 181 60 !Q:0,0|3,4|6,7|9,9|11,11|14,18|21,24|26,26|29,29|32,32|36,36|43,54 Q:1,2|5,5|8,8|10,10|12,13|19,20|25,25|27,28|30,31|33,35|37,42|55,59 ?SS--S??B?G-GG----?EE---?T-TS?EE?SSS?STTTTT?--------???GGGTS 1X4V|A PF01429.14_MBD_seed 16 152 !Q:3,3|6,9|14,14|21,23|27,48|56,67|69,69|72,72|88,134|136,137|141,143|150,150 Q:0,2|4,5|10,13|15,20|24,26|49,55|68,68|70,71|73,87|135,135|138,140|144,149|151,151 TTS?SS????BTTB?EEEEEE???SSS?--------------------?SEEEEEE?-----------T-TS?EESSHHHHHHHHTTS??--------------------------------------------?S??GGG???IIIIIS?S 1D9N|A PF01430.14_HSP33_seed 181 407 !Q:0,1|6,6|14,18|26,26|28,28|38,38|41,49|68,68|72,74|77,78|86,89|94,94|101,106|117,123|125,131|133,135|140,145|151,154|156,156|163,163|166,166|168,173|176,179|189,192|196,201|216,216|218,218|228,228|230,230|233,240|252,252|255,285|287,287|300,302|304,305|309,309|315,316|321,321|327,328|331,340|346,349|352,352|355,361|368,368|374,374|386,386|393,393|397,398|403,404 Q:2,5|7,13|19,25|27,27|29,37|39,40|50,67|69,71|75,76|79,85|90,93|95,100|107,116|124,124|132,132|136,139|146,150|155,155|157,162|164,165|167,167|174,175|180,188|193,195|202,215|217,217|219,227|229,229|231,232|241,251|253,254|286,286|288,299|303,303|306,308|310,314|317,320|322,326|329,330|341,345|350,351|353,354|362,367|369,373|375,385|387,392|394,396|399,402|405,406 ??EEEE-EEETTTT-----EEEEEEE?H-HHHHHHHHH-HT-------??HHHHHHHHHHHHHHHHHH-TTS?--TT-?EEEEEEE?---SSTT?EEEEEE------ETTSEEEEEE-------S??????-S??-TTSS----??HHHHH---?S-SSEEEE-EE-E-----?ST----TEEEEEEEE?---SSS------SSHHHHHHHHHHHH?S?EEEEEEEEE?T-TS?-------EEEEEEEEEEE?TT?-----------------------------?H-HHHHHHHHHHTT---S??HHH-HHHHT??HHHH-HHHHH--SS?--------?EEEEE----EE?EE?????--HHHHHH-HHHTT?HHHHHHHHHHH-SEEEEE?TTT??EEEE--EH 1XJH|A PF01431.16_Peptidase_M13_seed 21 229 !Q:0,1|22,23|27,29|57,57|61,61|63,74|76,76|97,99|108,112|136,142|148,154|159,159|173,173|175,175|178,178|189,189|192,193|205,205|214,215|221,223|227,228 Q:2,21|24,26|30,56|58,60|62,62|75,75|77,96|100,107|113,135|143,147|155,158|160,172|174,174|176,177|179,188|190,191|194,204|206,213|216,220|224,226 ??EEEGGGTEEEEEGGGSSTTT??TTS?--HHHHHHTHHHHHHHHHHHTTSTTGGGB?TTS?B?---------??S?HHHHHHHHHHHHHHHHHHHT???GGGTTSSS?????TTTSHHHHHHHHHHHHHHHHHHH-------HHTTT?????--BTTB?HHHHHHHHHHHHT?E-EE?HHHHHHHHHH?SS??HHHHHHHHHTT?HHHHHHHT??TTSTT???GGG?? 1DMT|A PF01432.15_Peptidase_M3_seed 29 599 !Q:4,6|24,31|48,50|56,56|70,70|106,109|114,117|120,121|138,146|154,154|157,157|163,163|179,179|181,181|184,199|204,204|213,215|218,219|228,228|230,231|234,234|236,236|239,241|248,249|251,256|258,288|292,293|296,296|303,311|314,318|321,322|324,325|330,330|346,348|357,358|360,365|390,393|397,420|438,438|456,456|459,460|463,469|471,471|483,484|486,488|490,496|498,500|504,507|509,509|513,513|515,517|520,520|534,535|548,548|551,555|574,574|586,588|598,598 Q:0,3|7,23|32,47|51,55|57,69|71,105|110,113|118,119|122,137|147,153|155,156|158,162|164,178|180,180|182,183|200,203|205,212|216,217|220,227|229,229|232,233|235,235|237,238|242,247|250,250|257,257|289,291|294,295|297,302|312,313|319,320|323,323|326,329|331,345|349,356|359,359|366,389|394,396|421,437|439,455|457,458|461,462|470,470|472,482|485,485|489,489|497,497|501,503|508,508|510,512|514,514|518,519|521,533|536,547|549,550|556,573|575,585|589,597 HHHH???HHHHHHHHHHHTTTTHH--------HHHHHHHHHHHHHHHH---HHHTT?SSHHHHHHTTSTT?SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH----HHHT????SS??TTTHHHHHHHHHHHHT?------??HHHHHTT?BH-HHHHH-HHHHHHHHHHTEEEE-E?TT?-------------??SSTT?EEEEEEET---TT??EEEEEEEE?S??TT-S?SS--?EEEEEE??E------E-----?-------------------------TTS?-EE?EEEEEE?????---?BT-----TB??B??HHHH-HHHHHHHHHHHHHHH???SSGGGSTT-?S?-----TTTTTHHHHHHHGGGGSHHHHHHT?-??TTT???-------------------??HHHHHHHHHGGGTTHHH-HHHHHHHHHHHHHHHTT?SS??HH-------H-HHHHHHHHTTS--S???T-------T?-?GGG----G?GGG-G---TT?TTTTTHHHHHHHH--HHHHHHHTHHHH?TT?----HHHHHHHHHHTTTTGGGS?HHHHHHHHHSS???SHHHHHHTT? 1I1I|P PF01433.15_Peptidase_M1_seed 33 469 !Q:1,2|16,18|20,21|23,25|28,28|30,31|44,47|50,52|59,60|62,63|66,68|74,75|84,88|101,104|112,114|117,117|119,125|136,137|139,142|144,145|157,160|172,172|174,174|183,183|185,186|190,191|205,206|213,213|217,218|233,237|240,240|244,245|250,251|255,256|260,260|263,264|266,266|268,268|274,274|303,306|309,313|322,322|324,324|327,328|332,333|345,347|351,351|353,353|394,394|405,405|407,408|411,411|422,423|434,437|439,441|444,445|449,450|461,461 Q:0,0|3,15|19,19|22,22|26,27|29,29|32,43|48,49|53,58|61,61|64,65|69,73|76,83|89,100|105,111|115,116|118,118|126,135|138,138|143,143|146,156|161,171|173,173|175,182|184,184|187,189|192,204|207,212|214,216|219,232|238,239|241,243|246,249|252,254|257,259|261,262|265,265|267,267|269,273|275,302|307,308|314,321|323,323|325,326|329,331|334,344|348,350|352,352|354,393|395,404|406,406|409,410|412,421|424,433|438,438|442,443|446,448|451,460|462,468 S??SSEEEEEEEEEEE---E??S??-TT-S??EEEEEEEEEEEE----SS-??SEEEEE??S-?EE?-?BTTBS--EEEEESTT?????EEEEEEETTTTE----EEEEESS???TT?E-------EEEEEEEEEE??S----S--SSEEEEEEEEE----TTEEEEEEEEE?T-TTTGGGTS?B??STT??BEEEEEEEEETTS--EEEESS?BSS??EEETTEEEEEEEEB???-?SB?GGG??EEEE??EEE--EEE?TT--S?E-EEEEE?HHHHHTTTTHHHHHHHHHHHHHHHHHTT????SS-----EEEEEEES-S?SS--SEE??TTEEEEEGGGT???TTT-S?HHHHHHHHHHHHHHHHHHHBTTTEEESSGGGTHHHHHHHH-HHHHHHHHHH?G--GG?GGGGHHHHTH--HHHHHHTTST----T???SS??GGG??SHHHHHHTSS-HHHHHHH 3FUE|A PF01434.13_Peptidase_M41_seed 31 218 !Q:0,0|12,24|48,52|56,76|78,81|106,107|109,110|132,134|138,138|140,161|163,163 Q:1,11|25,47|53,55|77,77|82,105|108,108|111,131|135,137|139,139|162,162|164,217 ?HHHHHHHHHHH???????-?????HHHHHHHHHHHHHHHHHHHHSTT?????EEE?????????????????????S---?BHHHHHHHHHHHTHHHHHHHHHHS--S??GGGHHHHHHHHHHHHHHHHTS???TTT?S????????-?????????????S?HHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHSEEEHHHHHHH 2DI4|A PF01435.13_Peptidase_M48_seed 21 361 !Q:23,23|26,36|38,39|55,58|60,61|63,65|72,72|78,88|90,92|101,102|113,157|160,160|182,183|204,204|213,214|216,218|267,287|297,332|336,337|339,341|349,349|352,353 Q:0,22|24,25|37,37|40,54|59,59|62,62|66,71|73,77|89,89|93,100|103,112|158,159|161,181|184,203|205,212|215,215|219,266|288,296|333,335|338,338|342,348|350,351|354,360 HHHHHHHHHHHHHHHHHTHHHHS?EE-----------E??SSHHHHHHHHHHHHT----T??E---EEEEEE?GGGTB-----------S???EEEEESSS-?EEEEEEHHHH----?????????????????????????????????????????HH-HHHHHHHHHHHHHHTTHHHHH--HHHHHHHHHHHHHHHHHHTT?SHHHHHTT??S???HHHHHHHHHHTTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTHHHH---------------------HHHHHHHHH------------------------------------HTT??S???HHHHHHS?SS??HHHHHHH 3C37|A PF01436.16_NHL_seed 108 32 !Q:2,2|9,11|14,15|21,22 Q:0,1|3,8|12,13|16,20|23,31 BS?EEEEEE?--TT??EEEEE--GGGTEEEEE 3FVZ|A PF01437.20_PSI_seed 95 113 !Q:0,0|4,13|16,16|18,18|24,26|28,28|30,30|36,40|45,48|50,50|53,77|79,91|96,101|104,106|108,112 Q:1,3|14,15|17,17|19,23|27,27|29,29|31,35|41,44|49,49|51,52|78,78|92,95|102,103|107,107 ?GGG------?--?SH-H-HHHHS?-?T-T?EEETT-----TTEE----E?GG-------------------------G?????????----EEET------TS?-?S?--?? 3AFC|A PF01441.14_Lipoprotein_6_seed 42 198 !Q:0,15|60,62|67,71|73,76|97,100|103,107|137,142|151,151|156,158|192,197 Q:16,59|63,66|72,72|77,96|101,102|108,136|143,150|152,155|159,191 ------------????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTEEEETTT---EEEE?---?S?--?HHHHHHHHHHHHHHHHHHHT???-TT-----THHHHHHHHHHHHHHHHHHHHTHHHHSSS?---??HHHHHHHH?TTSS?-?TTTHHHHHHHHHHHHHHHHHHHHHHHHHHGGGG-????? 2GA0|A PF01442.13_Apolipoprotein_seed 46 330 !Q:0,37|46,51|94,99|119,136|142,147|171,188|214,216|227,227|230,230|248,249|283,283|293,296 Q:38,45|52,93|100,118|137,141|148,170|189,213|217,226|228,229|231,247|250,282|284,292|297,329 -----------------------??---??????????TTHHHHHH------HHHHHHHHHHHGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHH------HHHHHHHHHHHHHHHHHHH------------------HHHHH------HHHHHHHHHHHHHHHHHHHHHHH------------------HHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHHHGGG?SS?HHHHHHHHHHHHHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSSS?HHHHHHHHH----HHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHH 1YA9|A PF01443.13_Viral_helicase1_seed 72 287 !Q:5,5|9,9|18,19|23,26|32,32|46,46|49,53|71,75|87,87|94,95|102,102|110,110|114,119|123,126|132,136|143,143|148,149|159,159|163,166|168,169|172,178|184,186|190,191|194,194|197,200|219,220|222,232|241,242|251,253|255,256|259,259|261,265|268,268 Q:0,4|6,8|10,17|20,22|27,31|33,45|47,48|54,70|76,86|88,93|96,101|103,109|111,113|120,122|127,131|137,142|144,147|150,158|160,162|167,167|170,171|179,183|187,189|192,193|195,196|201,218|221,221|233,240|243,250|254,254|257,258|260,260|266,267|269,286 EEEEE?TTS?HHHHHHHH??TTT---?EEEES?HHHHHHHHHHHTT-TS?????TTTEEEHHHHHHTTTSS?????SEEEEETGGGS?HHHHHH--HHHHTT?SEEEEEE?TTS??????STT????HHHHS??--?SEEEEE?EESS??HHHHHHHHT-TSS----S??EE???????EEEEE???GGG??TT-TS-???SEEEESSHHHHHHHHTTT??S----------?EETGGGTT??EEEEEEEE???S??TT?S-----TT?HHHHHHHSSEEEEEEEEE 1W36|D PF01447.13_Peptidase_M4_seed 13 190 !Q:8,8|12,18|31,32|38,38|43,45|55,62|64,64|67,67|69,75|77,77|85,85|87,90|115,117|121,123|126,128|136,140|142,143|146,148|152,152|159,162|164,165|169,170|174,174 Q:0,7|9,11|19,30|33,37|39,42|46,54|63,63|65,66|68,68|76,76|78,84|86,86|91,114|118,120|124,125|129,135|141,141|144,145|149,151|153,158|163,163|166,168|171,173|175,189 EEEEEEEE?TTS?------EEEEEEEEETTE--EESEE?SSSS?--EEEEEEEEE--------S?SS?E-------E?EESSSEE?S----GGGHHHHHHHHHHHHHHHHHHHHH???TTT---TS???EEEEEEE-----S--SS???EEE?SSSEEE????S--SSB??GGG?HHHHHHHHHHHHHHT 3T8G|A PF01448.19_ELM2_seed 53 111 !Q:0,2|6,6|9,21|24,29|32,32|34,56|61,63|66,66|68,76|78,81|84,84|86,88|94,100|104,104 Q:3,5|7,8|22,23|30,31|33,33|57,60|64,65|67,67|77,77|82,83|85,85|89,93|101,103|105,110 ???STT-TS-----????????TT??????ST-T-----------------------TEEE---EE?S---------S---?SS?H---HHHHH-------HHH-HHHHHH 4BKX|A PF01450.14_IlvC_seed 19 291 !Q:35,36|60,60|69,69|116,116|121,127|130,130|144,145|148,153|176,177|190,190|211,211|227,230|245,248|258,258|272,272|274,279|282,282|286,286|290,290 Q:0,34|37,59|61,68|70,115|117,120|128,129|131,143|146,147|154,175|178,189|191,210|212,226|231,244|249,257|259,271|273,273|280,281|283,285|287,289 HHHHHHHHHHHHHTTTTHHHHHHHHHHHHHHHHTT??HHHHHHTTHHHHHTHHHHHHHHT?HHHHHHTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHHHHHHTTS?BTTB???????SS?SHHHHHHHHHHHT??TT??????HHHHHHHHHHHHHHHHHHHHHT??HHHHHHHHTHHH-HHTTHHHHHHHHHHHHHTTS?HHHHHHHHHHHHHHH----HHHHHTHHHHHHTT????HHHHHHHHH?THHHHHHHHHTTS?S??????TT?SSS?GGG? 1QMG|A PF01451.16_LMWPc_seed 27 161 !Q:27,27|41,41|46,49|61,69|71,72|76,78|82,82|89,89|101,102|104,105|107,107|109,109|118,119|125,125|128,131|133,135|138,141 Q:0,26|28,40|42,45|50,60|70,70|73,75|79,81|83,88|90,100|103,103|106,106|108,108|110,117|120,124|126,127|132,132|136,137|142,160 EEEEESSSSSSHHHHHHHHHHHHHHHT?GGGEEEEEEEESS?TTTT????HHHHHHHHHTT????-????B??TTH---HHH?SEEEES-SHHHHHHHHHH??T--T?S?EEEEGGGG??TTSSS?SS????T---TS?---HHHHHHHHHHHHHHHHHHH 2FEK|A PF01453.19_B_lectin_seed 128 228 !Q:0,0|5,10|14,14|16,17|20,20|23,32|34,37|42,42|47,47|49,49|52,54|59,59|61,62|65,93|99,111|115,117|122,125|129,129|131,131|134,134|138,138|140,143|145,157|165,176|178,182|187,187|189,192|195,195|200,200|203,203|205,206|211,227 Q:1,4|11,13|15,15|18,19|21,22|33,33|38,41|43,46|48,48|50,51|55,58|60,60|63,64|94,98|112,114|118,121|126,128|130,130|132,133|135,137|139,139|144,144|158,164|177,177|183,186|188,188|193,194|196,199|201,202|204,204|207,210 ?EEET------TEE-E?-TT?EE----------E----ETTE-EEEE?T-TS?--EEEE-E--TT-----------------------------EEEEE?----------??TTS?--SSEE----EEE?T-TS?EEE-E----E-------------TTEEEEE??-----??--?S?-???EEEE?T----TS?EEEE?TT-S-?EEEE???-----------??? 3A0E|A PF01454.14_MAGE_seed 47 315 !Q:12,15|30,36|41,42|58,58|68,129|137,137|139,174|176,205|223,223|225,225|236,256|261,269|278,278|280,280|282,295|298,302|309,310 Q:0,11|16,29|37,40|43,57|59,67|130,136|138,138|175,175|206,222|224,224|226,235|257,260|270,277|279,279|281,281|296,297|303,308|311,314 HHHHHHHHHHHT?--?EEHHHHHHHTTGGG-------GGGH--HHHHHHHHHHHHHHH?EEEEESSTT-------------------------------------------------------------?SEEEEEE?S????----------------????--????---???H------------------------------HHHHHHHHHHHHHHTTT?B?HHHHHHHHHH??????-?----??????-??HHHH---------HHHHHHHT?E-E??-???????????EE-?--?HHHHTT??HHHH 3NW0|B PF01455.13_HupF_HypC_seed 170 106 !Q:0,2|4,5|10,13|16,23|25,26|32,34|36,43|47,47|49,50|57,57|62,62|64,71|74,74|76,76|83,84|88,88|92,92|100,100 Q:3,3|6,9|14,15|24,24|27,31|35,35|44,46|48,48|51,56|58,61|63,63|72,73|75,75|77,82|85,87|89,91|93,99|101,105 ???S??EEEE----EE--------E--TTEEE---E--------EET-T--EEEEEE?TTST-T------??TT?E-EEEETT--EEE-EEE?HHHHHHH-HHHHH 3VYU|A PF01457.11_Peptidase_M8_seed 8 619 !Q:0,59|62,62|65,65|68,69|74,74|84,85|89,89|93,93|97,97|101,102|106,108|131,131|135,136|142,147|155,157|164,169|173,173|181,184|187,190|192,194|202,202|205,205|207,207|215,216|220,222|224,227|244,244|247,249|256,256|258,258|264,264|268,268|271,304|309,310|323,323|326,328|332,333|336,336|345,345|349,349|358,358|360,361|363,363|365,366|379,379|382,382|386,390|395,396|403,403|405,408|416,416|420,435|438,441|444,444|451,452|455,456|458,460|464,465|468,476|482,482|484,484|490,492|498,507|514,514|519,519|526,528|538,539|542,542|544,554|575,575|578,578|581,581|584,585|588,588|590,590|597,597|601,601|604,604|608,610|618,618 Q:60,61|63,64|66,67|70,73|75,83|86,88|90,92|94,96|98,100|103,105|109,130|132,134|137,141|148,154|158,163|170,172|174,180|185,186|191,191|195,201|203,204|206,206|208,214|217,219|223,223|228,243|245,246|250,255|257,257|259,263|265,267|269,270|305,308|311,322|324,325|329,331|334,335|337,344|346,348|350,357|359,359|362,362|364,364|367,378|380,381|383,385|391,394|397,402|404,404|409,415|417,419|436,437|442,443|445,450|453,454|457,457|461,463|466,467|477,481|483,483|485,489|493,497|508,513|515,518|520,525|529,537|540,541|543,543|555,574|576,577|579,580|582,583|586,587|589,589|591,596|598,600|602,603|605,607|611,617 -----------------------------------------------------------?EE?SS?EE??EEEE?HHHHSTTSS??STT?EEE?SSS?EEE??GGG???HHHHHHHHHTHHHHHHHHHHTT-EEE??EESEE??????STTGGGS???HHHHHT-----?EES?SEEEEEE????ST----T???EEEEEEE?TT-S?EEEEEEE??GGG???S--??HHHHHHHHHHHHHHTT?SH---HHHHHT-T?EEEES?GGG?SS---------------------------------?EEEE??HHHHHHHHHHHT?TT???EEB??SS?TTTTTSSB?TTT?TTBTTSSS?S--S?B??HHHHHHHHHTTS?EE?GGG?????TTTT??HHHHHS?S----EETTEES?TTT-???-------?????BB--??TT?SEEEEE??EE?-S???GGG??SS---------STTEE?S?TTTTT???EEEEE----------EEETTS?GGGS?TTTGGG???STTEEEEEE--EE?B?????--????EEEEEEEEEEETTTTEEEEE?TT?SS?EE??TT?E-EEGGGT?SSB?TT?EEE???HHHHHTT? 1LML|A PF01458.12_UPF0051_seed 122 276 !Q:1,2|15,15|18,18|22,23|28,42|50,50|61,61|63,63|66,66|73,73|76,84|87,87|89,89|97,98|101,101|103,103|105,105|113,113|115,117|129,130|134,134|143,146|149,149|160,160|164,165|176,176|178,182|184,186|197,197|200,201|215,216|220,220|231,232|236,236|245,245|247,249|261,262|274,274 Q:0,0|3,14|16,17|19,21|24,27|43,49|51,60|62,62|64,65|67,72|74,75|85,86|88,88|90,96|99,100|102,102|104,104|106,112|114,114|118,128|131,133|135,142|147,148|150,159|161,163|166,175|177,177|183,183|187,196|198,199|202,214|217,219|221,230|233,235|237,244|246,246|250,260|263,273|275,275 S-?EEEEEEEEEEEE?TT?EEE--EEEE---------------EEESSSS?EEEEEEEEEE-E?TT?EEEEEE-EE??------?TT?E-EEEEEEE--EE?T-T?EEEEEEE-E???SEEEEEEEEEE-?STT?EEEEEEEE?-??TT?EEEEEEEEEE?SSS-?EEEEEEEEEE?T-----T?--EEEEEEEEEE?TT?-TTEEEEEEEEEEE?-STT?EEEEEEEEEE??SSE-EEEEEEEE-E???HHHHHHHHHTT??HHHHHHHHHHH-H 1VH4|A PF01459.17_Porin_3_seed 90 477 !Q:0,0|2,2|8,22|24,24|33,35|39,40|47,59|66,91|100,105|113,176|182,182|194,195|198,201|211,211|215,220|226,227|233,233|236,236|248,253|255,255|267,267|284,286|295,296|298,331|340,340|343,348|359,360|362,363|366,366|380,397|402,411|423,424|435,435|444,446|450,450|462,462|465,469|472,473 Q:1,1|3,7|23,23|25,32|36,38|41,46|60,65|92,99|106,112|177,181|183,193|196,197|202,210|212,214|221,225|228,232|234,235|237,247|254,254|256,266|268,283|287,294|297,297|332,339|341,342|349,358|361,361|364,365|367,379|398,401|412,422|425,434|436,443|447,449|451,461|463,464|470,471|474,476 ?S?STTTT????-???????-??S?EEEEEEEE??-TTT-?EEEEEE-------------EEESSS?-----------------------??EEEEEEEE???---SBEEEEE----------------------------------------------------------------EEEET-TTEEEEEEEEE??TT??--EEEEEEEEE?TTT??----EEEEE--EEEEE?SS?EEEEEEEESSS------S?EEEEEEEEEET-TEEEEEEEEEETTTTS???EEEEEEEE-?S----------------------------------SEEEEEEE-ET------TTEEEEEEEE??S--TT?EEEEEEEEETTSS-----------------?EEEE----------EEEEEEEETTE--EEEEEEESSS?EEEEEEEE?--SSS?EEEEEEEESTT?GG-----GT??EEE 2K4T|A PF01462.13_LRRNT_seed 26 37 !Q:0,3|10,15|21,21|25,26|28,29|31,32|34,36 Q:4,9|16,20|22,24|27,27|30,30|33,33 ???-TTSEEE------TTEEE?TTS??S--S??S??? 3TWI|D PF01463.19_LRRCT_seed 59 30 !Q:1,1|3,4|12,13|18,19|21,21|29,29 Q:0,0|2,2|5,11|14,17|20,20|22,28 T?B??BSTTTTT-?BGGG??H-HHHHHTT? 3RFE|A PF01464.15_SLT_seed 39 164 !Q:12,12|27,27|30,30|32,38|41,65|72,72|85,89|91,93|113,116|125,132|143,143|157,157|159,159 Q:0,11|13,26|28,29|31,31|39,40|66,71|73,84|90,90|94,112|117,124|133,142|144,156|158,158|160,163 HHHHHHHTTSSS?HHHHHHHHHHHHTT?TT?B?------TT?-----------------------?BTTTTB?HHHHHHHHHHHT??---S???GGGGGSHHHHHHHHHHHHH----HHHHHTTS-------?HHHHHHHHHH?HHHHHHHHHHHTT?S?HHHH 2ZQ4|A PF01465.15_GRIP_seed 44 49 !Q:0,1|20,23|29,30|39,40 Q:2,19|24,28|31,38|41,48 ??HHHHHHHHHHHHHHTTSS----HHHHH--HHHHHHTT??HHHHHHHH 1UPT|B PF01466.14_Skp1_seed 62 100 !Q:0,27|36,36|48,52|58,58|60,61|71,76|78,78|82,84|87,87|94,95|98,99 Q:28,35|37,47|53,57|59,59|62,70|77,77|79,81|85,86|88,93|96,97 ?????????--??--???-----?????HHHHTTTT?HHHHHHHHHHH-----HHHHT-T??HHHHHHHTT??????H-HHH---HH-HHHHHH--HH?? 3L2O|A PF01467.21_CTP_transf_2_seed 65 233 !Q:4,5|8,9|25,25|27,30|36,36|39,39|43,50|53,53|68,68|71,71|75,76|81,81|84,86|89,107|118,118|122,122|131,131|138,150|162,162|168,169|171,171|173,175|178,178|187,187|193,193|195,195|205,206|211,225 Q:0,3|6,7|10,24|26,26|31,35|37,38|40,42|51,52|54,67|69,70|72,74|77,80|82,83|87,88|108,117|119,121|123,130|132,137|151,161|163,167|170,170|172,172|176,177|179,186|188,192|194,194|196,204|207,210|226,232 EEEE??TT??HHHHHHHHHHHHHHT?S?---EEEEE?SS?TTS?-?----?SS?HHHHHHHHHHHHTT?TT-EEE??HHHH?SS???HH-------------------HHHHHHHHHH?TTS?EEEEEEHH-HHHHGG-------------GSTTHHHHHHH?EEEEE??T-T?-?SS?SSHHHHHH-HHHHB?S?TTHHHHSSS??EEEE??????-------??HHHHHHH 1N1D|A PF01468.12_GA_seed 102 60 !Q:7,8|27,28|31,31|45,46 Q:0,6|9,26|29,30|32,44|47,59 HHHHHHH??HHHHHHHHHHHHHHHHTT??SS?HHHHHHHHHHHHH??SHHHHHHHHHHHH 1PRB|A PF01470.12_Peptidase_C15_seed 9 212 !Q:0,0|8,10|13,13|15,16|28,29|42,42|60,61|70,70|73,74|80,80|85,85|87,89|91,92|94,95|99,102|105,105|111,111|116,117|119,119|132,133|139,141|161,162|165,166|171,171|173,173|184,184|186,189|191,192|211,211 Q:1,7|11,12|14,14|17,27|30,41|43,59|62,69|71,72|75,79|81,84|86,86|90,90|93,93|96,98|103,104|106,110|112,115|118,118|120,131|134,138|142,160|163,164|167,170|172,172|174,183|185,185|190,190|193,210 ?EEEEEEE???SS?S??HHHHHHHHHTT-?EETTEEEEEEEE?SSTTHHHHHHHHHHHHH??SEEEEEEE?TT??SEEEE?EEES?B??-S--S??TTS????SB?SSTTS?SEEE??S?HHHHHHHHHHTT??EEEES???SSHHHHHHHHHHHHHHHHS??SB??EEEE?B?HHHHHHHHHT-T????B??HHHHHHHHHHHHHHHHHH? 1Z8T|A PF01471.13_PG_binding_1_seed 237 87 !Q:13,16|18,18|20,26|29,42|44,48|51,52|64,64|70,72|74,75|77,77|79,79 Q:0,12|17,17|19,19|27,28|43,43|49,50|53,63|65,69|73,73|76,76|78,78|80,86 BSHHHHHHHHHTT----T?S------?TT???---------??S-----SB??HHHHHHHHHHH-HHTTS?-?S--S?B?HHHHHHH 1SLM|A PF01472.15_PUA_seed 108 98 !Q:5,5|15,16|18,20|30,30|33,40|43,43|51,54|57,66|76,76|83,83|85,86 Q:0,4|6,14|17,17|21,29|31,32|41,42|44,50|55,56|67,75|77,82|84,84|87,97 TEEEE?GGGHHHHHT--T?-?EEGGGEEEE?TT?------?TT?EEEEEET----TT?--------?EEEEEEESS?HHHHHH?S--SSEEEEEEEET 2AB4|A PF01473.15_CW_binding_1_seed 213 26 !Q:0,0|5,5|7,8|10,11|15,15|19,20|24,24 Q:1,4|6,6|9,9|12,14|16,18|21,23|25,25 ?EEEE-E--T--TEE-EEE-?TTS?B 2J8F|A PF01474.11_DAHP_synth_2_seed 111 595 !Q:6,8|13,14|17,23|38,39|42,43|62,62|69,69|72,73|77,77|103,103|110,110|113,118|120,120|123,131|133,136|141,144|149,149|159,160|188,189|192,192|197,203|210,210|223,232|245,248|252,253|256,261|264,297|304,306|316,337|339,355|361,387|393,393|399,399|403,404|416,417|419,419|425,425|428,429|441,441|444,449|458,460|480,484|489,490|498,498|500,501|504,504|527,530|532,535|542,542|545,554|559,559|564,564|566,566|573,575|579,580|582,582|595,595 Q:0,5|9,12|15,16|24,37|40,41|44,61|63,68|70,71|74,76|78,102|104,109|111,112|119,119|121,122|132,132|137,140|145,148|150,158|161,187|190,191|193,196|204,209|211,222|233,244|249,251|254,255|262,263|298,303|307,315|338,338|356,360|388,392|394,398|400,402|405,415|418,418|420,424|426,427|430,440|442,443|450,457|461,479|485,488|491,497|499,499|502,503|505,526|531,531|536,541|543,544|555,558|560,563|565,565|567,572|576,578|581,581|583,594 HHHHHH---HHTS??TT??-???-HHHHHHHHHHHTTS??SS-?HHHHHHHHHHHHHHHTTS?EEEEEE?SS??STT?SHHHHHHHHHHHHHHHHHHHHHHTS?EEEEEE?SS??????S?SB--------?T----TSSB????TTTS?SSSSHHHHS??TTHHHHHHHHHHHHHHHHHHHHTSGGG?-HH-HHHH-------HHHHHH-HHSTTHHHHHHH----------HHHHHHHHHHHH----HTT??GG------GS------------------------------????EEEEEE???HHHHHHTEE----------------------E-------------?--?SSSSS-------------------------??EEETT?SEEEE?TTS??TTSHHHHHHHH??S?EEEEE?TT??HHHHHHHHHHH?TT----??TTSEEEEE???TTTHHHHHHHHHHHHHTTT??--?EEEE??SGGGEEE?T--TS?EEEBHHHHHHHHHHHHHHHHHH----T????EEEEEB?SS------????SBBT-TTTB?T-TGGGTS???SSS??B?HHHHHHHHHHHH- 2YPP|A PF01475.14_FUR_seed 24 129 !Q:3,6|22,23|37,38|42,45|67,67|69,69|72,72|78,82|85,86|95,96|101,102|118,118 Q:0,2|7,21|24,36|39,41|46,66|68,68|70,71|73,77|83,84|87,94|97,100|103,117|119,128 HTT????HHHHHHHHHHTSGGG--SSEEHHHHHHHHH--HTT????HHHHHHHHHHHHHTTSEEEEE?G-GG?EEEEE??---SS??EEEEETTT??EEEE??HHHHHHHHHHHHHTT?EEEEEEEEEE 2FE3|A PF01476.15_LysM_seed 156 81 !Q:2,3|6,9|18,38|40,41|50,59|61,61|63,63|66,72|75,75 Q:0,1|4,5|10,17|39,39|42,49|60,60|62,62|64,65|73,74|76,80 EE??TT?--?HHHHHHHH---------------------T??HHHHHHHH----------T?S?TT----???TT?EEEEE 4A52|A PF01477.18_PLAT_seed 84 172 !Q:6,6|8,11|15,16|18,18|21,22|30,30|33,33|35,38|42,42|45,53|55,55|57,57|59,59|66,68|71,77|88,108|111,114|121,121|125,131|134,136|139,139|144,149|152,152|155,155|159,166 Q:0,5|7,7|12,14|17,17|19,20|23,29|31,32|34,34|39,41|43,44|54,54|56,56|58,58|60,65|69,70|78,87|109,110|115,120|122,124|132,133|137,138|140,143|150,151|153,154|156,158|167,171 EEEEEE-E--??STT??B?SE--EEEEEEE-SS?B-???EEE?SS?--------B?T-T?EEEEEE??-SS----???SEEEEEEEEE-------------------??SS??-?EEEEEE-EEE?------TT?-?EE-EEEE------EE-EE?TTS--------EEEEE 2WXT|A PF01478.13_Peptidase_A24_seed 103 293 !Q:10,11|14,20|24,30|36,40|54,57|62,62|66,66|79,87|97,227|231,231|245,252|254,254|256,259|272,272|284,284 Q:0,9|12,13|21,23|31,35|41,53|58,61|63,65|67,78|88,96|228,230|232,244|253,253|255,255|260,271|273,283|285,292 HHHHHHHHHH--HH???????THH-------HHHHH-----HHHHHHHHHHHHH----HHHT?HHH-HHHHHHHHHHHH---------HHHHHHHHS-----------------------------------------------------------------------------------------------------------------------------------STT?SSHHHHHHHHTTS?-------S?S????SHHHHHHSSSSS?HHHHHHHHHHH-HHHTTHHH 3S0X|A PF01479.20_S4_seed 155 52 !Q:7,8|28,28|36,38|41,41|43,46|49,49|51,51 Q:0,6|9,27|29,35|39,40|42,42|47,48|50,50 TBHHHHT--TTTSSSSSHHHHHHHHHTT?BBSSSSB???TT?B??--TT?B? 3KIX|d PF01480.12_PWI_seed 34 100 !Q:18,19|31,53|58,61|74,74|97,97 Q:0,17|20,30|54,57|62,73|75,96|98,99 SGGGHHHHHHHHHHHHSS??SHHHHHHHHHT-----------------------TSSS?--?HHHHHHHHTTTS?SHHHHHHHHHHHHHHHHHTTSS-SS 3V53|A PF01481.11_Arteri_nucleo_seed 4 122 !Q:0,62|67,68|87,87|93,93|97,97|105,107|118,121 Q:63,66|69,86|88,92|94,96|98,104|108,117 ---------------------------??------------------------??????????GGGG??HHHHHHHHHHHHHHHHHT?SEEEE?TTS?EEEEEEE???HHHHHHHHHH???? 2I9F|A PF01483.15_P_proprotein_seed 75 134 !Q:11,11|13,13|24,24|27,28|34,35|38,38|40,41|43,45|56,59|69,69|74,74|76,77|85,86|90,91|93,93|104,105|112,115|117,117|119,124 Q:0,10|12,12|14,23|25,26|29,33|36,37|39,39|42,42|46,55|60,68|70,73|75,75|78,84|87,89|92,92|94,103|106,111|116,116|118,118|125,133 EEEEEEEEEEE?S-SGGGEEEEEE?TT??EEEEE?-SS?S??H---HHHHHHHTSS????EEEEEEEEE?TTTT?B??EEEEEEE--EEB??S?EEEEEEESSS??EEEEEE????S?E------EEEEEEEEE 3HJR|A PF01485.16_IBR_seed 166 161 !Q:2,4|9,13|18,19|22,22|24,27|33,41|43,44|46,46|49,49|52,54|58,58|61,64|66,114|117,117|119,124|127,128|135,135|138,143|145,154|157,159 Q:0,1|5,8|14,17|20,21|23,23|28,32|42,42|45,45|47,48|50,51|55,57|59,60|65,65|115,116|118,118|125,126|129,134|136,137|144,144|155,156|160,160 HH---HHHH-----HHHH--HH-H----SSTTE---------E--E?SS-SS???EEE?SS????E-------------------------------------------------EE?S------SS-?EEETTT?SB?----?S----------SS--?H 1WD2|A PF01487.10_DHquinase_I_seed 150 310 !Q:4,5|7,10|22,25|33,34|37,37|40,52|55,55|71,73|76,76|81,103|106,113|117,117|120,125|127,130|145,152|161,161|163,163|167,167|171,175|185,185|193,193|197,200|204,206|210,213|220,220|224,224|232,233|242,242|254,254|256,256|259,260|265,265|275,275|281,282|287,288|293,293|298,299 Q:0,3|6,6|11,21|26,32|35,36|38,39|53,54|56,70|74,75|77,80|104,105|114,116|118,119|126,126|131,144|153,160|162,162|164,166|168,170|176,184|186,192|194,196|201,203|207,209|214,219|221,223|225,231|234,241|243,253|255,255|257,258|261,264|266,274|276,280|283,286|289,292|294,297|300,309 EEEE??S????HHHHHHHHTTS-??-SEEEEEG--GG?TT-------------TT?HHHHHHHHHHHHHHS--?SS?EEEE?--?-------------------BG--------GGT?SB-?--??H----HHHHHHHHHHHHHT------??SEEEEEGG-G?HHH-HHH-----HHHHHHHTT?EEEEEEE-ESS????HHH---HHH----HHHHHH-HTT?SEEEEEE??SSHHHHHH-HHHHHHHHHHH-T?SS??EEEE?TGGGTHHHH?HHHHT??EEEE--BSSS?SSTT??BHHHHHHHHH 3S42|A PF01488.15_Shikimate_DH_seed 44 170 !Q:8,12|14,14|16,16|23,24|38,40|47,47|61,65|67,67|69,71|73,74|80,82|88,88|93,93|95,96|101,114|116,116|125,127|130,130|133,135|137,137|142,143|146,146|149,149 Q:0,7|13,13|15,15|17,22|25,37|41,46|48,60|66,66|68,68|72,72|75,79|83,87|89,92|94,94|97,100|115,115|117,124|128,129|131,132|136,136|138,141|144,145|147,148|150,169 HHHHHHHS---??T-T?EEEEES??HHHHHHHHHHHHH-??SEEEEE?SSHHHHHHHHHHH-----T?E---E??GGGHH---HHHHT?SEEE-E??SSSS?------------?B?HHHHHHHH---HH?SS???E-EEEE??SS?SB?TTGGGSTTEEEEEHHHHHHH 4FQ8|A PF01491.11_Frataxin_Cyay_seed 96 156 !Q:0,1|23,27|29,49|51,51|58,58|67,67|69,69|72,72|79,80|84,84|91,91|100,116|118,118|121,122|124,124|129,129|132,134|150,155 Q:2,22|28,28|50,50|52,57|59,66|68,68|70,71|73,78|81,83|85,90|92,99|117,117|119,120|123,123|125,128|130,131|135,149 ??HHHHHHHHHHHHHHHHHHHHH?--??S---------------------S?EEEEEE-TTEEEEEE-T-TS?EEEEEE??TTT?EEEEET-TEEEEEEE?----------------S-SS--E-EETT-TT?-?HHHHHHHHHHHHHSS?-???? 4JPD|A PF01493.14_GXGXG_seed 29 286 !Q:5,5|8,9|27,45|56,56|63,64|69,81|89,89|91,92|98,98|107,108|111,123|125,125|130,133|140,141|151,152|159,170|173,173|180,182|189,189|197,197|199,211|213,213|218,219|225,227|231,245|251,251|255,255|259,261|264,264|266,275 Q:0,4|6,7|10,26|46,55|57,62|65,68|82,88|90,90|93,97|99,106|109,110|124,124|126,129|134,139|142,150|153,158|171,172|174,179|183,188|190,196|198,198|212,212|214,217|220,224|228,230|246,250|252,254|256,258|262,263|265,265|276,285 EEEEE?TT??STTHHHHHHHHHHHTTT?-?--------------??EEEEEEEEEE?TTTTTT??TTEE-------------EEEEEEE?T--TTTTT?EEEEEEEE??TT?-----------?S?GGGS????TTTTTT??EEEEEEEEE??SSTTTT?-----------SS?EEEEEE?-?SSTTTT?EEEEEEE?S???----------S?TTTT??EEEEE???TTS--------------?HHHHS?TTT?EEE---ES?S----------HHHHHHHHHH 1LLW|A PF01494.14_FAD_binding_3_seed 20 452 !Q:5,5|8,9|24,24|31,32|37,37|42,44|46,48|50,51|54,54|66,66|74,76|78,80|88,92|95,96|107,107|111,111|114,115|118,119|138,140|143,143|152,154|156,156|162,162|165,167|175,176|179,179|182,185|188,192|196,198|210,212|216,217|220,220|222,224|235,237|240,240|248,251|270,272|279,283|288,288|292,292|295,311|316,316|319,319|321,321|328,344|360,360|379,379|381,381|391,391|398,399|403,404|429,429 Q:0,4|6,7|10,23|25,30|33,36|38,41|45,45|49,49|52,53|55,65|67,73|77,77|81,87|93,94|97,106|108,110|112,113|116,117|120,137|141,142|144,151|155,155|157,161|163,164|168,174|177,178|180,181|186,187|193,195|199,209|213,215|218,219|221,221|225,234|238,239|241,247|252,269|273,278|284,287|289,291|293,294|312,315|317,318|320,320|322,327|345,359|361,378|380,380|382,390|392,397|400,402|405,428|430,451 EEEEE-EE??SHHHHHHHHHHHHH-HHHSTT??EEEE?SSSS???S?--S??EE?HHHHHHHHHTT?HHHHHTT?--B???EEEEEEE----?TT??EEEEEEEESS?TTS?SS??EE??HHHHHHHHHHHHHHHTTT???EE?SEEEEEEE---E?GGGTT?TT???EEEEEEE??GG-GS??-?SS?????SSS???HHHHHHHHHTS???STT??TT?E---EEEEEEEEEE???TT?HHHHHHT??-?EEEEEEEEEEEEEEEEEE-??TTTTSE-----EEEE?SSS?EE-----------------EEEE?ST-T?EEEEEE?????????????????HHHHHHHHHHHHTTS?EEEEEEEEEEEEEEEEEE?S?SEETTTEEE?GGGTEE??STT??HHHHHHHHHHHHHHHHHHHHTTSB?GGGGHHHHHHHHHHHHHHHHHH 3ZYX|A PF01497.13_Peripla_BP_2_seed 33 349 !Q:3,4|15,17|19,19|26,27|31,32|40,53|56,67|74,74|76,94|101,102|108,108|112,121|133,133|137,140|145,161|178,178|180,181|203,203|206,211|223,228|233,233|245,245|247,248|252,253|256,264|267,267|271,271|278,279|281,282|291,306|312,312|314,315|321,321|323,326|333,333|340,340|345,345 Q:0,2|5,14|18,18|20,25|28,30|33,39|54,55|68,73|75,75|95,100|103,107|109,111|122,132|134,136|141,144|162,177|179,179|182,202|204,205|212,222|229,232|234,244|246,246|249,251|254,255|265,266|268,270|272,277|280,280|283,290|307,311|313,313|316,320|322,322|327,332|334,339|341,344|346,348 EEE??HHHHHHHHHT---T?GGGEEE??GGG??GGGGGGT--------------TS---------???EETTEE?H-------------------HHHHHH??SEEEE?TTT----------GGGHHHHHHHS?EEE????TTSH-----------------HHHHHHHHHHHHHHHT?H--HHHHHHHHHHHHHHHHHHTTS?TT-----?EEEEEEEETTE------EEEE?TTSTTTHHHHT-S??EES-?TT??-----??SS?EEE?HHHHHH--H??SEEEEEEH----------------HHHHT?S??HHHHS?S----HHHHTS-HHHHTT?EEEE?HHH 2R7A|A PF01498.13_HTH_Tnp_Tc3_2_seed 26 78 !Q:10,17|26,29|31,32|34,34|46,77 Q:0,9|18,25|30,30|33,33|35,45 HHHHHHHHHH???----?HHHHHHHT----T??S?HHHHHHHHHHT?????????????-?????????????????? 1U78|A PF01499.11_Herpes_UL25_seed 15 651 !Q:0,53|55,179|182,182|188,189|195,195|214,216|219,220|234,236|244,245|249,251|267,269|272,273|276,276|293,309|330,330|332,333|335,336|338,344|349,349|352,353|355,355|359,363|384,388|390,407|410,411|416,418|425,426|428,431|459,460|464,464|468,468|470,471|478,478|480,501|504,515|535,535|538,539|544,544|556,575|582,585|600,607|632,632|634,635|639,639|650,650 Q:54,54|180,181|183,187|190,194|196,213|217,218|221,233|237,243|246,248|252,266|270,271|274,275|277,292|310,329|331,331|334,334|337,337|345,348|350,351|354,354|356,358|364,383|389,389|408,409|412,415|419,424|427,427|432,458|461,463|465,467|469,469|472,477|479,479|502,503|516,534|536,537|540,543|545,555|576,581|586,599|608,631|633,633|636,638|640,649 ----------------------------??------------------------E-----------------------------------------------------------------------------------------------------------------------------EE?SSTTS??EEESS?HHHHHHHHHHHSGGGSSS?-?EE??HHHHHHHHHHHHH?--GGGGGTS??GGG???HHHHHHHHHHHHHTT???SS??SS?HHHHHHHHHHHHHHHH??-?????????----?SHHHHHHTHHHHHHHHHHHH?S-?S--S???????GGGS?SS??S?TTS?---?STTTTTTSHHHHHHHHTTSS?????S???---????????????TT?-HHHH---HHHHHH??S????GGGSHHHHHHHHHHHHHHHHHHHHHTT??TTS?GGG?S??HHHHST-T??????---??????-??????SS?-----------SSHHHHHHHHHTHHHHHHH?TT??HHHH?HHHHHHHHHHS??????????------????SHHHHT----HHHHHHHHHHHHHT??-?????HHHHHHHHHHHHHHHHHHHHHHHH?S??STG-GGHHHHHTTT? 2F5U|A PF01501.15_Glyco_transf_8_seed 67 434 !Q:6,6|10,43|58,58|61,91|93,94|103,104|127,128|134,157|160,162|166,167|179,203|205,208|210,210|212,212|217,217|223,224|226,227|233,235|237,237|246,271|286,287|290,292|294,295|304,304|312,312|321,322|329,333|335,336|349,364|370,371|377,377|386,393|395,397|406,407|410,410|415,420|422,424|426,427|433,433 Q:0,5|7,9|44,57|59,60|92,92|95,102|105,126|129,133|158,159|163,165|168,178|204,204|209,209|211,211|213,216|218,222|225,225|228,232|236,236|238,245|272,285|288,289|293,293|296,303|305,311|313,320|323,328|334,334|337,348|365,369|372,376|378,385|394,394|398,405|408,409|411,414|421,421|425,425|428,432 EEEEEE?GGG----------------------------------HHHHHHHHHHHHHT?TT-------------------------------S??EEEEEESS??HHHHHHHHHTSGGGTTTEEEEE??GGGGT------------------------TS???STT??GGGGGGGGHHH-------------------------H?--?S?S?EEEE?TTEEE-?S??HHHHT???T-TSSEEEEE?-------------------------HHHHTSTTSGGGGT??TT---S??EEEEEEEE?HHHHTTS?HHHHHHHH--HHHSTT-----T??STHHHHHHHHHT----------------TSEEE??GGGSB?HHHHHHHT??---???S???HHHHHHSS??SS?SEEE?----?S---S??TTSTT? 3T7N|A PF01502.13_PRA-CH_seed 168 93 !Q:5,5|18,18|26,26|38,39|44,44|49,49|62,67|70,72|74,74|78,83|85,85|90,91 Q:0,4|6,17|19,25|27,37|40,43|45,48|50,61|68,69|73,73|75,77|84,84|86,89|92,92 EEEEE?HHHHHHHHHHSB?EEEETTT-TEEEETTTTTS??EEEE-EEEE?TTSSEEEEEEEE------SS?--S-STT------S-BSSS??E 1ZPS|A PF01503.12_PRA-PH_seed 53 184 !Q:9,12|14,14|16,21|28,35|42,48|52,52|70,77|80,112|125,131|144,171 Q:0,8|13,13|15,15|22,27|36,41|49,51|53,69|78,79|113,124|132,143|172,183 HHHHHHHHT????S-S????-?HHHHHH--------HHHHHH-------HHH-HHHHHHHHHHHHHHHTT????----GG---------------------------------GGHHHHHHHHHH-------HHHHHHHHHHTT-----------------------?--?-HHHHHHHHHHHH 2YF4|A PF01504.13_PIP5K_seed 117 667 !Q:4,7|10,17|20,40|44,44|55,56|58,60|65,86|91,92|107,133|136,137|139,142|149,174|177,179|182,184|189,215|221,221|224,227|230,231|233,234|236,242|247,254|256,258|262,317|319,321|324,327|329,336|340,349|351,351|354,360|368,368|370,379|405,405|412,431|433,435|437,437|442,447|453,560|563,565|575,576|579,599|602,602|611,613|617,649|659,659|666,666 Q:0,3|8,9|18,19|41,43|45,54|57,57|61,64|87,90|93,106|134,135|138,138|143,148|175,176|180,181|185,188|216,220|222,223|228,229|232,232|235,235|243,246|255,255|259,261|318,318|322,323|328,328|337,339|350,350|352,353|361,367|369,369|380,404|406,411|432,432|436,436|438,441|448,452|561,562|566,574|577,578|600,601|603,610|614,616|650,658|660,665 HHHH----SS??------EE??????----------???-?EEE?TTSSEEEEEE-?H---HHHH----------------------HHHH--HHHHHHHHHHHTTT?-------------------------?SS??E----EEEEEE--------------------------EE---TT---EEEE---------------------------EEEEE?SS---?SS--S??S-------EEEE--------E??-SSS?---------------------------????------------------------H---HH----H--------TSS----------S?EE?------HHHHHHT-T----??????HHHHHHHHHHHHHHHHHHHHTTEES?EEEEEE--------------------E---E-HHHH------HHHHH????????????????????-----------------------------------------------------------------------?????????????????TT???TTTSTTEEE??TT-----------------?---SS?EEEEEEEE???EES?--????????????????-?-----???????HHHHHHHHH-HHHHHH? 2GK9|A PF01505.13_Vault_seed 85 75 !Q:1,4|7,7|14,15|18,24|27,31|33,52|56,56|64,65|67,68|71,74 Q:0,0|5,6|8,13|16,17|25,26|32,32|53,55|57,63|66,66|69,70 S????SS?EEEEEE??EE----??-TT-----S??------------------EES?EEEEEES--G--GG???? 2ZUO|A PF01506.14_HCV_NS5a_seed 19 23 !Q: Q:0,22 TTHHHHHHHHHHHHHHHHHHHHH 1R7G|A PF01507.14_PAPS_reduct_seed 27 311 !Q:5,6|25,26|28,45|48,49|54,55|57,59|74,76|78,80|85,102|107,117|127,166|172,173|175,175|180,183|189,189|194,195|201,201|204,205|207,207|211,215|218,224|227,227|232,233|238,239|252,255|257,258|260,310 Q:0,4|7,24|27,27|46,47|50,53|56,56|60,73|77,77|81,84|103,106|118,126|167,171|174,174|176,179|184,188|190,193|196,200|202,203|206,206|208,210|216,217|225,226|228,231|234,237|240,251|256,256|259,259 SEEEE??SSHHHHHHHHHHHHHHTT--S----------------??SS?-EEEE??S???HHHHHHHHHHHHTT---T??-EEEE??????????????????HHHH-----------HHTHHHHHH----------------------------------------HHHHH--T?SEEE????TTSSG-GGGG??SEEEE?TT??B?GGG?????SS???????TT?EEEE?-TTTT??HHHHHHHHHHHT????S??S??????????????????????????????????????????????????? 3G59|A PF01509.13_TruB_N_seed 171 208 !Q:2,4|7,11|13,16|18,22|28,30|33,33|44,44|54,54|57,58|79,79|81,82|84,86|89,102|106,109|115,115|119,119|122,122|127,129|132,132|134,135|150,162|173,175|179,180|182,184|187,193|202,202|205,206 Q:0,1|5,6|12,12|17,17|23,27|31,32|34,43|45,53|55,56|59,78|80,80|83,83|87,88|103,105|110,114|116,118|120,121|123,126|130,131|133,133|136,149|163,172|176,178|181,181|185,186|194,201|203,204|207,207 HH---HT-----T---?S----?EEESS???TT?EEEEEEEEGG-GGGGTHHHH-TS?-EEEEEEEEETEEESSSBTTS?E--E---EE?-------????-?HHH----HHHHH-HTT-SE-EEEE???SS-S??EETTEEHHHHHHTT--????---???-EEEEEEEEEE---EEE--E---TT-------EEEEEEEE?TT??H 2AB4|A PF01510.20_Amidase_2_seed 117 361 !Q:0,2|4,5|7,8|18,19|21,26|32,43|55,57|62,63|66,66|70,72|76,76|78,83|86,91|93,94|96,96|99,101|106,115|117,118|121,121|123,165|169,176|180,183|185,186|190,190|194,195|197,198|200,233|235,249|254,254|257,259|262,263|266,267|272,278|280,280|284,288|290,290|296,318|322,323|326,332|339,354|356,356|358,358 Q:3,3|6,6|9,17|20,20|27,31|44,54|58,61|64,65|67,69|73,75|77,77|84,85|92,92|95,95|97,98|102,105|116,116|119,120|122,122|166,168|177,179|184,184|187,189|191,193|196,196|199,199|234,234|250,253|255,256|260,261|264,265|268,271|279,279|281,283|289,289|291,295|319,321|324,325|333,338|355,355|357,357|359,360 ???B??S--SEEEEEEEE??S??--??SHHHH------------HHHHHHHHHHH---HHTT??SS?SSS---EEE?T------TS?-----E--E-ES---STTT----------B??SS-S?------------------------------------------TTT--------GGG----E--EEE-EES--S??S----------------------------------S??-----------??HHHH-HH---HH--HH--HHHH-------H-HHT-----S-EEEEE-----------------------EEE--EH-------HHHSSS?---------------T-T?HH 1S2J|A PF01512.12_Complex1_51K_seed 123 216 !Q:5,5|7,7|12,15|25,25|27,27|29,29|31,38|44,47|51,52|61,61|65,66|79,79|81,82|89,89|92,92|103,108|111,114|127,127|132,133|141,142|144,144|161,182|185,186|191,191|195,199|201,201 Q:0,4|6,6|8,11|16,24|26,26|28,28|30,30|39,43|48,50|53,60|62,64|67,78|80,80|83,88|90,91|93,102|109,110|115,126|128,131|134,140|143,143|145,160|183,184|187,190|192,194|200,200|202,215 HHTTT?B?TTTT--??BHHHHHTTS?S-S?S?-----??EEEEE????STT??SHHHHHHH?HHH--HHHHHHHHHHHH-T??EEEEEE?TT?HHHHHHHHHH------HH----HHHHTTSSBTTG-GGSS??BEEEEEE??S?GGGGSHHHHHHHHTTS---------??????----?--SS?-TTTS?GGG-----S?EEEEEHHHHHTHHH 3I9V|1 PF01513.16_NAD_kinase_seed 33 439 !Q:6,33|48,54|62,124|128,129|131,131|138,138|146,146|160,162|165,166|172,173|176,177|180,180|183,184|199,199|201,202|208,213|216,242|251,265|280,280|286,286|289,290|309,337|341,341|354,355|358,358|361,363|371,376|380,383|387,387|390,391|397,397|400,401|403,404|418,418|421,421|428,428|431,432|438,438 Q:0,5|34,47|55,61|125,127|130,130|132,137|139,145|147,159|163,164|167,171|174,175|178,179|181,182|185,198|200,200|203,207|214,215|243,250|266,279|281,285|287,288|291,308|338,340|342,353|356,357|359,360|364,370|377,379|384,386|388,389|392,396|398,399|402,402|405,417|419,420|422,427|429,430|433,437 EEEEEE???--------------------?????HHHHHHHHHHHTTT?------EEEEEES???????????????????------------------------------------------??EEE??S?TTTTTT?SEEEEES?HHHHHHHHHHHHH---TT??EEEEE?-SS??SS?SE--EGGGHHHHHHHHHH-T??EEEEE?----?EE---------------------------EEEEETTE---------------EEEEEEESSEEEEE?SSSSS?EE--EEEEETTEEEEEEEESEE-----------------------------EEE?TGGGGSHHHHTT??EE?TT???EEEEEES?-----SSS????EEE?TT??EEEEE?TT--S??EEEEETTTEEEEE?TT?EEEEEE?SS?-EEEEE? 2QVL|A PF01514.12_YscJ_FliF_seed 21 231 !Q:0,30|32,39|47,47|63,65|70,70|74,75|97,98|100,105|110,118|153,167|176,176|179,181|183,183|200,201|203,207|217,230 Q:31,31|40,46|48,62|66,69|71,73|76,96|99,99|106,109|119,152|168,175|177,178|182,182|184,199|202,202|208,216 ------?------------------------E--------EEEEEEE?HHHHHHHHHHHHHTT???EEEE?TTS-?EEEEEEGGGHHHHHHHHHHTT?-S??????HHHH?????????HHHHHHHHHHHHHHHHHHHHTTSTTEEEEEEEEE????------?????EEEEEEEE?TT???G-GGHHHHHHHHHHHSTT??G-----GGEEEEEEE--------?????? 2Y9J|Y PF01515.14_PTA_PTB_seed 21 346 !Q:0,0|11,16|19,20|25,26|45,45|47,47|53,55|62,63|68,70|73,73|78,78|82,82|86,86|102,103|113,113|128,128|134,134|138,138|152,153|157,159|167,167|170,177|192,192|195,196|216,216|218,219|225,225|227,227|233,233|251,251|255,256|263,263|269,269|280,281|287,288|292,292|310,311|324,324|328,329|332,333|346,346 Q:1,10|17,18|21,24|27,44|46,46|48,52|56,61|64,67|71,72|74,77|79,81|83,85|87,101|104,112|114,127|129,133|135,137|139,151|154,156|160,166|168,169|178,191|193,194|197,215|217,217|220,224|226,226|228,232|234,250|252,254|257,262|264,268|270,279|282,286|289,291|293,309|312,323|325,327|330,331|334,345 ?HHHHHHHHHH------HS??EEEE??TTSHHHHHHHHHHHHHTS?E-EEEES--?HHHHHH--HHTT???TT-SEEE?TTT?TTH-HHHHHHHHHHHGGGT??HHHHHHHTT-SHHHHHHHHHHHTS?SEEEE?TTS?HHHHHHHHHHHTB??SSS???EEEEEEE?TT??------STBTTEEEEESSSS?SS??HHHHHHHHHHHHHHHHHHH?S??EEEEE?S?SSSSS?SHHHHHHHHHHHHHHHH?TTS--EEEEEE?HHHHH?HHHHHHHSTT-?SSTTT??EEE?SSHHHHHHHHHHHHHHS??EEEEEEEESBSS?EEE??TT??HHHHHHHHHHHH- 1QZT|A PF01519.11_DUF16_seed 18 211 !Q:0,19|23,23|36,53|64,70|82,125|143,178|196,202|210,210 Q:20,22|24,35|54,63|71,81|126,142|179,195|203,209 ---------?????------TTB?BHHHHHHHHTTB-----------------?BHHHHHHHHH-------HHHHHHHHHHH--------------------------------------------HHHHHHHHHHHHHHHHH------------------------------------HHHHHHHHHHHHHHHHH-------HHHHHHT? 2BA2|A PF01520.13_Amidase_3_seed 103 379 !Q:5,11|13,16|19,19|21,48|51,54|57,62|64,64|73,73|79,79|82,82|86,86|88,90|98,98|101,101|103,127|135,144|146,150|153,155|158,158|166,182|186,193|201,201|204,205|221,227|232,248|264,266|271,271|277,277|280,286|290,297|301,322|326,331|335,340|346,348|367,367 Q:0,4|12,12|17,18|20,20|49,50|55,56|63,63|65,72|74,78|80,81|83,85|87,87|91,97|99,100|102,102|128,134|145,145|151,152|156,157|159,165|183,185|194,200|202,203|206,220|228,231|249,263|267,270|272,276|278,279|287,289|298,300|323,325|332,334|341,345|349,366|368,378 EEEEE??-----B----TT-B?---------------------?-----SB?---TT?----?B-HHHHHHHH-HHHHH-HH-HTT?T---TEEEEES?SS-S-----???----------------?HHHHHHH----------H-----HH---TT?SEEEEEE??-??------------SSS?-?----?SBEEEEE?SS??SSHHHHHHHHHHHTH-------HHHH?????????????????HHHHHHHHHHHHHHH---HHHH-HTTTS?BS-------SSS-------?EEE?--------------------?GGG--??--TTS-----?EEEEE???TTSHHHHHHHTSHHHHHH-HHHHHHHHHHH 3NE8|A PF01521.15_Fe-S_biosyn_seed 98 139 !Q:0,0|5,7|19,19|21,21|25,33|39,39|42,42|46,60|68,69|71,77|80,81|84,84|86,86|89,90|95,95|97,98|105,105|114,115|123,123|128,128 Q:1,4|8,18|20,20|22,24|34,38|40,41|43,45|61,67|70,70|78,79|82,83|85,85|87,88|91,94|96,96|99,104|106,113|116,122|124,127|129,138 ?BEEE--?HHHHHHHHHTT?T-TSE---------EEEEE?SS?STT??--???????-???EEEEEES--S??-----TT??EE?B?SS??EEEE?H--HHHTTS?SSEEEEEE--TTEEEEE-ETTE-EEEEEEEEEE 2APN|A PF01522.16_Polysacc_deac_1_seed 104 293 !Q:2,4|17,48|64,65|69,69|72,72|75,75|77,79|83,83|87,87|93,152|156,156|161,162|178,178|180,181|184,185|190,190|194,195|203,211|218,219|222,223|230,230|247,248|250,255|257,258|261,261|265,273|277,280|289,290 Q:0,1|5,16|49,63|66,68|70,71|73,74|76,76|80,82|84,86|88,92|153,155|157,160|163,177|179,179|182,183|186,189|191,193|196,202|212,217|220,221|224,229|231,246|249,249|256,256|259,260|262,264|274,276|281,288|291,292 SS???TTEEEEEEEETB--------------------------------HHHHHTHHHHHHHHT??EEE-EE?HH-H---HTS?TTS?EEETT------------------------------------------------------------EEE?GGGB??HHHHHHHHHHTSEEE?B??SS??SEEE?STT??EEEGGGS??-------EETTTT--EE??HHHHHH-HHHHHHHHHHHHHHHH--H??-???E--EE?GGG?------??HHH----HHHHHHTT??EE 2IW0|A PF01523.11_PmbA_TldD_seed 158 461 !Q:5,8|12,14|16,16|23,23|26,26|30,31|36,36|47,52|55,58|61,61|65,65|71,75|78,78|81,86|89,89|97,98|100,103|107,113|116,123|126,126|129,130|135,135|138,174|178,184|191,191|201,202|210,212|250,259|264,265|267,272|282,299|302,303|308,312|317,320|329,330|332,334|336,338|340,340|343,343|345,346|350,350|360,360|364,367|379,382|385,389|392,399|401,404|408,408|410,410|413,414|418,418|421,426|428,429|431,431|434,435|438,438|441,441|443,447|455,455|458,460 Q:0,4|9,11|15,15|17,22|24,25|27,29|32,35|37,46|53,54|59,60|62,64|66,70|76,77|79,80|87,88|90,96|99,99|104,106|114,115|124,125|127,128|131,134|136,137|175,177|185,190|192,200|203,209|213,249|260,263|266,266|273,281|300,301|304,307|313,316|321,328|331,331|335,335|339,339|341,342|344,344|347,349|351,359|361,363|368,378|383,384|390,391|400,400|405,407|409,409|411,412|415,417|419,420|427,427|430,430|432,433|436,437|439,440|442,442|448,454|456,457 SEEEE----EEE---E-EEEEEE-EE?TTS??EEEE-EEEEEEEEEE------EE----TT-EEE-EEEES---??SH-HH------HH-HHHHHHH--H----HTT-------SS??-----?TT?SS??GGGB?SS---------??????????------------??---?HHH-------HHHHHH-HHHHHHHHS?-TTEEEEE---EEEEEEEEEEEEEEETTTEEEEEEEEEEEEEEEEEEE------????EEEE--E------EEEEESSGG------------------GS??HHHH-----HHHH----HHHHHHTS--S--?B???S?EE-E--EEE?HHHHHHHHH-HHH----HHSBHHHHHTT--??TT-----TT-------?T----TSB?S?TT??EEE?TT---?--T--T?SS??SS?TT?B??-??EEEEETT-EE??? 1VPB|A PF01527.15_HTH_Tnp_1_seed 45 107 !Q:0,7|19,19|26,26|37,38|50,58|62,62|64,67|69,89|103,103 Q:8,18|20,25|27,36|39,49|59,61|63,63|68,68|90,102|104,106 ???-????HHHHHHHHHHH-TTGGGS?HHHHHHHHTS-?HHHHHHHHHHH?------??STT?S????H---------------------HHHTHHHHHHHHH?GGG 2RN7|A PF01530.13_zf-C2HC_seed 33 36 !Q:3,3|5,5|8,9|13,13|17,17|21,24|26,26|32,32 Q:0,2|4,4|6,7|10,12|14,16|18,20|25,25|27,31|33,35 TTS?S?SS??SBS?SSS-SSS----B?SSTTT?TTT 2CS8|A PF01532.15_Glyco_hydro_47_seed 139 1553 !Q:11,26|28,28|42,54|56,56|58,83|85,92|95,95|109,119|121,121|123,140|152,157|160,200|202,204|206,216|221,247|252,263|275,276|278,326|329,346|355,355|361,362|366,367|369,370|372,372|375,384|389,412|415,421|423,427|430,436|439,499|501,507|520,531|537,538|555,564|566,567|572,573|577,580|584,585|588,588|590,678|680,746|750,750|758,763|766,773|779,787|793,794|796,798|800,837|840,866|873,899|909,909|913,913|915,917|921,935|939,939|941,945|947,960|962,964|970,973|994,995|997,1019|1026,1026|1041,1041|1045,1047|1053,1096|1098,1120|1123,1129|1133,1301|1305,1306|1308,1325|1339,1340|1357,1357|1360,1361|1363,1367|1370,1397|1399,1399|1401,1402|1405,1405|1408,1408|1410,1427|1429,1445|1447,1447|1449,1475|1477,1477|1481,1482|1494,1494|1496,1508|1512,1513|1515,1537|1544,1544|1548,1548|1552,1552 Q:0,10|27,27|29,41|55,55|57,57|84,84|93,94|96,108|120,120|122,122|141,151|158,159|201,201|205,205|217,220|248,251|264,274|277,277|327,328|347,354|356,360|363,365|368,368|371,371|373,374|385,388|413,414|422,422|428,429|437,438|500,500|508,519|532,536|539,554|565,565|568,571|574,576|581,583|586,587|589,589|679,679|747,749|751,757|764,765|774,778|788,792|795,795|799,799|838,839|867,872|900,908|910,912|914,914|918,920|936,938|940,940|946,946|961,961|965,969|974,993|996,996|1020,1025|1027,1040|1042,1044|1048,1052|1097,1097|1121,1122|1130,1132|1302,1304|1307,1307|1326,1338|1341,1356|1358,1359|1362,1362|1368,1369|1398,1398|1400,1400|1403,1404|1406,1407|1409,1409|1428,1428|1446,1446|1448,1448|1476,1476|1478,1480|1483,1493|1495,1495|1509,1511|1514,1514|1538,1543|1545,1547|1549,1551 HHHHHHHHHHH----------------H?TTSSEEETTTTEE-------------E?S--------------------------S--------SS?HHHHHHHHHHHHT-----------T?H------------------HHHHHHHHHHH------HH?--?---------------??----------------???-E---E-----------EHHH---------------------------HHHH------------HHHHHHHHHHH--H-----------------------------------------------??HH------------------HHHHHHHH-HHHHG--GGG-?S--S-SS?-------??SEEE------------------------TT-------T??---EE???????EE-------------------------------------------------------------H-------HHHTSSHHHHHH------------HHHHH??THHHHHHHHHHHHHHH---------?S??BTTB??SEE---?TTT??EE-S-----------------------------------------------------------------------------------------T-------------------------------------------------------------------TEE?SSTTTHH------HH--------HHHHH---------HHHHT--T---S?--?----------------------------------HH---------------------------HHHHHH---------------------------HHHHHHHHH-TEE-E?--TTT-------------??EEE?E-----E--------------E---TTEEE?---EEEGGGGHHHHHHHHHHHTT??H-----------------------HHHHHH-HHHHHHHHHHHHTS-TTS???SEEEE?------------------------------------------?S---------------------??TT-----??SEE??-----------------------------------------------------------------------------------------------------------------------------------------------------------------------GGG??B????--------------HHHHHHHHHHHHH??THHHHHHHHHHHHHHH-HT--B?----TT----------------------------S?B??BS?TT?T------------------T?--??------------B?S--------------------------?B?HHH--HHTHHHHHHHH-T?----------??TTT--T?----------------------TTTEEE?TTS?EEE? 1FMI|A PF01534.12_Frizzled_seed 11 377 !Q:3,3|41,41|76,114|120,121|125,125|129,129|168,174|176,177|198,198|214,214|257,259|314,330|332,335|358,358|370,376 Q:0,2|4,40|42,75|115,119|122,124|126,128|130,167|175,175|178,197|199,213|215,256|260,313|331,331|336,357|359,369 TTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHS?TTTTHHHHHHHHHHHHHHHHHGGGSTTHHHHHHB?--------------------------------------TTSBB??SBS?TTS?SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS???????S??THHHHHHHHHHHHHHHHHHT?EEEETTTTEEEESSS?HHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTSSS---SSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?????????????????S????HHHHHHHHHHHHHHHHHHGGGG?SHHHHHHHHHH??????? 4JKV|A PF01535.15_PPR_seed 518 31 !Q:14,14|29,30 Q:0,13|15,28 HHHHHHHHHHHHHS?HHHHHHHHHHHHHT?? 3KD7|A PF01536.11_SAM_decarbox_seed 15 392 !Q:0,9|18,27|29,29|34,34|47,48|55,55|80,80|83,84|101,112|123,124|126,126|130,131|134,134|148,148|150,153|162,162|167,168|176,182|184,192|194,198|208,209|218,219|222,238|248,248|255,255|259,266|270,270|274,274|280,280|282,282|286,286|294,295|299,299|306,316|318,318|331,332|344,344|347,347|349,351|356,359|362,366|377,377|390,391 Q:10,17|28,28|30,33|35,46|49,54|56,79|81,82|85,100|113,122|125,125|127,129|132,133|135,147|149,149|154,161|163,166|169,175|183,183|193,193|199,207|210,217|220,221|239,247|249,254|256,258|267,269|271,273|275,279|281,281|283,285|287,293|296,298|300,305|317,317|319,330|333,343|345,346|348,348|352,355|360,361|367,376|378,389 ??????????EEEEEEEE??????????S?GGGS?HHHHHHHHHHTT??EEEEEE?SSEEEEEETTEEEEEESSEEEEEE?TT??GGGGHHHHHHHHHHTT??---------?EEEEEEEEEE??S?GGG??TT?SSHHHHHHHHHTT?S----SEEEEEEE?TTSS--EEEEEEE?-----?S------???S?????EEEEEEEES??HHHHGGGB??TT---------------??HHHHHHHHT?GGGSSS?EEE--------EEE?SSB?EEEEE-E?TTS?EEEEEEE??TTS?EEEEEE?-------???S?SHHHHHHHHHHH??SEEEEEEEEET-TS-S???TTSS????TT-----EEEEEEEEEE?SSEEEEEEEEEE?? 3EP7|B PF01537.12_Herpes_glycop_D_seed 22 140 !Q:6,7|16,19|28,29|36,37|51,57|71,71|75,75|78,81|86,87|90,93|102,107|113,114|118,118|129,129 Q:0,5|8,15|20,27|30,35|38,50|58,70|72,74|76,77|82,85|88,89|94,101|108,112|115,117|119,128|130,139 EEEEEE?-STTSEEEE????SHHHHHHT??TTGGGS-?EEEEEEEEEEETT-------EEEEEEEEEEEEE?TTS?TT--??SEEE??EE?---SSTTTEEE??????EEEES??GGG?EEEEEEEEET-TEEEEEEEEE 2C3A|A PF01538.13_HCV_NS2_seed 29 203 !Q:0,70|72,91|93,99|101,102|105,105|107,107|144,147|152,152|157,158|165,165|175,178|182,183|188,189|192,192 Q:71,71|92,92|100,100|103,104|106,106|108,143|148,151|153,156|159,164|166,174|179,181|184,187|190,191|193,202 -------------------------------------------------------------?--------?G--------------------G-------G??SS?S?HHHHHHHHHHHHHTTTTSTTHHHHHHHHHHHHHHHT????TTTS?GGGT??TTHHHH?SEETTEESS????EEE??STTT??TT?EETTEEEEEE 2KWZ|A PF01541.19_GIY-YIG_seed 105 154 !Q:0,1|8,11|14,19|22,42|44,47|53,53|55,56|59,59|64,64|68,69|73,79|84,85|87,87|93,96|102,103|110,110|115,118|123,130|144,147 Q:2,7|12,13|20,21|43,43|48,52|54,54|57,58|60,63|65,67|70,72|80,83|86,86|88,92|97,101|104,109|111,114|119,122|131,143|148,153 ??EEEEEE----ET------TT-------------------??E----EEEEE-S--SH-HHHH-HHH--HHH-------HHTT??S?HHHHH----HHHHH?-TTEEEE-EEEE????HHHH--------HHHHHHHHHHHTT----TTSSSS 1YD1|A PF01543.12_HCV_capsid_seed 5 126 !Q:0,3|5,5|7,7|11,13|22,23|26,27|40,125 Q:4,4|6,6|8,10|14,21|24,25|28,39 ????S?S?SSS???SSSTTTTT??SS??SSSSSSTTTSSS????---------------------------------------------------------------------------------- 1CWX|A PF01544.13_CorA_seed 79 413 !Q:0,0|3,3|5,5|10,10|13,13|15,15|25,31|34,35|39,39|43,49|52,53|56,57|61,66|68,68|71,71|92,97|104,104|117,121|123,130|139,143|146,146|153,153|188,198|201,203|213,214|217,219|222,222|227,230|243,249|254,261|264,264|270,270|274,275|286,289|316,322|331,333|341,341|347,348|355,383|388,389|405,410 Q:1,2|4,4|6,9|11,12|14,14|16,24|32,33|36,38|40,42|50,51|54,55|58,60|67,67|69,70|72,91|98,103|105,116|122,122|131,138|144,145|147,152|154,187|199,200|204,212|215,216|220,221|223,226|231,242|250,253|262,263|265,269|271,273|276,285|290,315|323,330|334,340|342,346|349,354|384,387|390,404|411,412 ?SS?B?EEEE?TT?H-HHHHHHHHH-------TT??HHH-HHH-------HH??SS??EEE------E?SS?EEEEEEEEEEETTTTEEEEE------EEEEEE-ETTEEEEEESSS---??S?-------HHHHHHHH-----TT?TTTTTS?SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----------HS???STHHHHHHH--HH---HH-HHHH----HHHHHHHHHHHH-------HHHH------??SS?THHHH-HHH--HHHHHHHHHH----HHHHHHHHHHHSTTTHHHHHHHHHHH-------HHHHHHHH---HHTTTST-TTHHH--HHHHTT????-?----??------??????----?HHHH--HHHHHHHHHHHHHHT------TS 4EV6|A PF01545.16_Cation_efflux_seed 89 584 !Q:10,10|18,21|23,23|27,33|53,71|74,74|76,76|81,87|89,91|93,94|112,112|120,124|132,151|160,185|189,193|196,196|207,264|268,296|298,345|349,352|354,354|364,366|369,370|372,375|379,381|386,386|389,411|415,432|462,467|472,474|482,482|484,491|496,496|498,499|501,506|510,514|516,517|520,520|523,523|528,531|533,533|539,548|562,563|566,570|572,578|580,583 Q:0,9|11,17|22,22|24,26|34,52|72,73|75,75|77,80|88,88|92,92|95,111|113,119|125,131|152,159|186,188|194,195|197,206|265,267|297,297|346,348|353,353|355,363|367,368|371,371|376,378|382,385|387,388|412,414|433,461|468,471|475,481|483,483|492,495|497,497|500,500|507,509|515,515|518,519|521,522|524,527|532,532|534,538|549,561|564,565|571,571|579,579 SHHHHGGGTT-TTTBTTB????T-TSS???????TTHHHHHHHHHHHHHHTTS-------------------SS-S?STTS-------S?--S??THHHHHHHTTTTTTSSS-TTGGGSS----?TTSSTTT--------------------SSSSTTTS-???-------------------?-?GGG-----SS?GGGGTTTHHH----------------------------------------------------------HGG-----------------------------G--------------------------------------------??--STT----S-GGGGGGHHH---HT??S----STT???TTSS?SS-----------------------TTS------------------SSSSSHHHHTTTTTTTTTTHHHHTGGGSS???-??TTHH---HHHHHHH-T--------TSSS?S-?B??????TTS?---?B??BS?TT-STTT?---S?GGGHH----------HHHHHHHHTTSSS??SS----?B-??-???S???? 3BYR|A PF01546.23_Peptidase_M20_seed 366 593 !Q:5,7|10,18|21,24|28,62|64,64|66,66|87,95|99,99|102,102|111,111|116,145|158,184|195,195|200,200|202,203|209,209|212,226|230,231|241,254|267,280|286,404|409,409|411,411|415,416|427,427|453,453|464,465|469,469|473,476|484,485|491,508|513,515|519,523|533,538|540,540|547,549|552,564|567,568|571,575 Q:0,4|8,9|19,20|25,27|63,63|65,65|67,86|96,98|100,101|103,110|112,115|146,157|185,194|196,199|201,201|204,208|210,211|227,229|232,240|255,266|281,285|405,408|410,410|412,414|417,426|428,452|454,463|466,468|470,472|477,483|486,490|509,512|516,518|524,532|539,539|541,546|550,551|565,566|569,570|576,592 EEEEE???BS?-??-????TT--??SST-----------------------------------T?B?TTSHHHHHHHHHHHHHHHHT?--------GGG?SS-EEEEEEES?TTTT-----?------------------------HHHHHHHTTTTT---------------------------TEEEEEEEEE-ETTS?T--TEEEE?SE---------------EEE??EEEEEEEEE??????????????HHHHHHHHHHHH??????????????EEEEE-----------------------------------------------------------------------------------------------------------------------EEEE?S?SSS??SEEEEEEEEE?SSHHHHHHHHHHHHHHHHHHHHHTT?EEEEEEEEEE??EEE?GGG----HHHHHHH--HHHTT?-----------------EEEE???BSS?---?THHHHHTTS-----?E-EEEEEE???SS------------?TT?-TT????-TTHHHHHHHHHHHHHHH 3VH9|A PF01547.20_SBP_bac_1_seed 129 523 !Q:6,8|15,15|18,21|23,26|29,29|34,36|40,41|45,49|56,57|69,72|81,84|91,93|99,100|102,102|104,105|114,114|116,117|119,127|131,131|143,149|153,154|161,162|164,164|169,177|184,188|192,193|195,210|215,215|232,232|234,248|250,250|255,257|276,277|289,310|313,313|319,320|330,332|336,337|339,339|346,347|357,367|370,370|377,377|381,389|392,413|420,420|425,425|430,433|435,435|439,442|445,450|455,455|462,462|464,468|472,475|481,488|495,518 Q:0,5|9,14|16,17|22,22|27,28|30,33|37,39|42,44|50,55|58,68|73,80|85,90|94,98|101,101|103,103|106,113|115,115|118,118|128,130|132,142|150,152|155,160|163,163|165,168|178,183|189,191|194,194|211,214|216,231|233,233|249,249|251,254|258,275|278,288|311,312|314,318|321,329|333,335|338,338|340,345|348,356|368,369|371,376|378,380|390,391|414,419|421,424|426,429|434,434|436,438|443,444|451,454|456,461|463,463|469,471|476,480|489,494|519,522 SHHHHH---HHHHHH-HH----H----HH-HSTT--?EEE--EEE?---?SSHHHH--HHHHHHHHTTT?---SSEEEEEE----ETTTHH---HHHHH--T?B??SHHHHHHH-T??G---------GGB?HHHHHHHTEET-------TEE??EEEEEE--E?EEEE---------EHHHHH-----HTT??S--------------??SBHH-HHHHHHHHHHHHHTTT?T---------------T?EEEE???SSSHHHHHHHHHHHHTTT??SEEEETTEEEE---------------------?TT?HHHHH--HHHHHHHHH---HTS??S?GGGGTT??HHHHHHHHH-----------TT?EEEEEE?THH---------HH----------------------HHTSTT?TTTT?EEEE??-?B?TTS????BE------EEEE-EEEBTT?S?----HHH----HHHHH--------HHHTSH------------------------HHHH 3G7W|A PF01549.19_ShK_seed 157 57 !Q:0,15|17,17|26,27|31,33|37,40|47,48|54,56 Q:16,16|18,25|28,30|34,36|41,46|49,53 ???----???------S?HHHHHTTT--TTT---TSH----HHHHHH-?HHHHT-?? 2LG4|A PF01551.17_Peptidase_M23_seed 276 190 !Q:3,6|11,14|16,22|24,25|27,35|37,38|41,41|48,49|55,59|61,65|68,69|76,79|83,84|92,93|97,107|110,111|119,119|121,123|125,130|132,139|141,143|146,157|162,162|165,166|168,168|170,181|184,184|188,189 Q:0,2|7,10|15,15|23,23|26,26|36,36|39,40|42,47|50,54|60,60|66,67|70,75|80,82|85,91|94,96|108,109|112,118|120,120|124,124|131,131|140,140|144,145|158,161|163,164|167,167|169,169|182,183|185,187 EEE?---SEEE----E??-----T--T?--------E--EE?SSSSBE--EEEEE----?G-----GG-?EEEEEE?---STT--EEEEEEE--ESB-??---?--??SB??SSSEEEE?B-??S------S-------?S---SS------------BEEE-EE--E-E------------SS-SEE?? 3UZ0|B PF01553.16_Acyltransferase_seed 57 250 !Q:6,8|15,32|34,34|41,44|46,48|56,56|63,65|67,67|73,73|78,78|84,85|95,96|102,104|111,131|149,149|158,176|181,181|184,189|191,193|195,195|197,211|214,215|217,222|236,236|240,240 Q:0,5|9,14|33,33|35,40|45,45|49,55|57,62|66,66|68,72|74,77|79,83|86,94|97,101|105,110|132,148|150,157|177,180|182,183|190,190|194,194|196,196|212,213|216,216|223,235|237,239|241,249 HHHHHH---HHHHHT------------------T?EEEEEE????T---THHHHHH-HHHTTT?--H-HHHHH?EEEE?THHHH?-TTTHHHHHT--SEEEE???GGGTTS---------------------SGGGHHHHHHHHHHHHH-HHHHHHHH?----------------??EEEE?TT?-----S???B?T---------------TT??B??????HHHHHHHHHHHHT-SSS?EEEEEEEEE 1IUQ|A PF01554.13_MatE_seed 58 190 !Q:10,19|33,34|55,63|76,76|80,80|110,110|118,118|121,121|127,132|152,152|163,163|167,169|180,180 Q:0,9|20,32|35,54|64,75|77,79|81,109|111,117|119,120|122,126|133,151|153,162|164,166|170,179|181,189 HHHHHHHHHH----------HHHHHHHHHHHHH--TTTTTTHHHHHHHHHHHHHH---------HHHHHHHHHGGG?TTS?SSSSSSSHHHHHHHHHHHHHHHHHHHHHH-HHHHHHH?SS?SSTTH------HHHHHHHHHHHHHHHHHHH-HHHHHHTTTT?TTS???HHHHHHHHHH-HHHHHHHHH 4HUM|A PF01555.13_N6_N4_Mtase_seed 49 649 !Q:6,9|12,12|15,54|58,59|62,71|79,83|95,103|115,115|121,196|207,209|218,230|232,235|238,251|253,253|255,257|263,278|285,340|345,345|347,349|363,363|367,384|386,390|393,393|395,396|400,410|412,548|557,557|561,562|564,571|573,573|580,584|587,594|605,605|607,629|633,633|637,637|643,644 Q:0,5|10,11|13,14|55,57|60,61|72,78|84,94|104,114|116,120|197,206|210,217|231,231|236,237|252,252|254,254|258,262|279,284|341,344|346,346|350,362|364,366|385,385|391,392|394,394|397,399|411,411|549,556|558,560|563,563|572,572|574,579|585,586|595,604|606,606|630,632|634,636|638,642|645,648 EEEEEE????SS?SS----------------------------------------GGG??SS----------HHHHHHH-----HHHHHHHHHHH---------EEEEEEEEEEE?HHHHH----------------------------------------------------------------------------HHHHHHHHTT--?EEEEEEEE???--------?-S????SS--------------S?B???EEEEE----------------EESSTT?----------------------------------------------------???GGGS?B???HHHHHHHHHHHTS?BTT------------------B?????TT?B??BSE-----------E--------------------------------------------------------------------------------------------------????????????????--------????------?????HHHHHHHH-HHH??T--------T?EEEESS----?TT-------?HHHHHHHHTT?E-----------------------EEE-EES?HHHHH--HHHH 3CJR|A PF01556.13_CTDII_seed 113 117 !Q:4,4|7,7|17,17|20,20|24,24|26,26|29,31|37,40|42,42|44,46|48,48|50,50|53,58|63,63|65,65|67,67|72,79|81,81|83,84|91,91|94,99|101,109|111,111 Q:0,3|5,6|8,16|18,19|21,23|25,25|27,28|32,36|41,41|43,43|47,47|49,49|51,52|59,62|64,64|66,66|68,71|80,80|82,82|85,90|92,93|100,100|110,110|112,116 EEEE-EE-EEEHHHHHH?EE-EEE-E?TT?-?EEEEE----E?S???T-T?EE------EETT?S?B?SSST--------T?B??EEEEEE-EE--??--S?-?---?--H-HHHHH 3AGY|A PF01557.13_FAA_hydrolase_seed 95 568 !Q:0,1|8,16|18,90|95,95|101,105|108,132|134,135|138,138|141,158|160,164|168,169|176,179|181,181|183,185|189,195|200,201|204,204|214,215|217,217|219,241|245,250|256,265|270,270|273,273|277,277|284,288|293,300|303,331|333,333|340,364|369,370|375,376|379,379|385,385|393,393|399,416|418,418|421,421|423,426|429,435|437,469|471,513|515,516|519,522|524,524|530,544|547,555|561,561|563,564 Q:2,7|17,17|91,94|96,100|106,107|133,133|136,137|139,140|159,159|165,167|170,175|180,180|182,182|186,188|196,199|202,203|205,213|216,216|218,218|242,244|251,255|266,269|271,272|274,276|278,283|289,292|301,302|332,332|334,339|365,368|371,374|377,378|380,384|386,392|394,398|417,417|419,420|422,422|427,428|436,436|470,470|514,514|517,518|523,523|525,529|545,546|556,560|562,562|565,567 ?-EEEESS?--------B?-----?????????----------------------------------------??????-----???----EEEE?GGGEE?----TT?----------------------?-E--EE?TT----------------??S-----EEE?-EEEEEE----E?S--?BSS?-----?GGGG--GG-GEEEEEEEE??E-E-----------------------HHH------HHHHS----------SSHH-HH?STT?EEEEEE-----EESS??------GG-----------------------------G?EEEEEE-------------------------TTEE--EEEE--EG-GGBSS?HHHHHHH-HHHHS-----------------?B?TT?E----EE????---S-??------------------------------E-------------------------------------------E??TT?---E-EEEEE---------------TT---------TEEEE-E--EEE 2Q1D|X PF01558.13_POR_seed 119 311 !Q:1,2|5,5|18,18|23,28|35,39|41,46|48,48|51,51|57,57|60,76|78,78|80,80|87,102|105,105|108,111|119,122|125,130|136,137|139,140|143,143|152,188|195,195|197,199|205,213|218,224|226,228|237,241|246,247|250,250|252,253|256,260|269,294 Q:0,0|3,4|6,17|19,22|29,34|40,40|47,47|49,50|52,56|58,59|77,77|79,79|81,86|103,104|106,107|112,118|123,124|131,135|138,138|141,142|144,151|189,194|196,196|200,204|214,217|225,225|229,236|242,245|248,249|251,251|254,255|261,268|295,310 T--TS?HHHHHHHHHHHH-HHTT---??-EEEEEE?????T------T?EE-EEEEE-EE?-?-??-----??????S-S?SEEEES----------------SG-GG?---SGGGGTT--??TT------SEEEE--E?-SS?HHHHHHHH??----------------------------------?SEEEEE?H---HHHHH---------HHTS-------S???HHHHHHHH-----HHHH?-SS?H--HH-----HHHHHHHH??-???-------------------?HHHHHHHHHHHHHHHH 2C3M|A PF01563.11_Alpha_E3_glycop_seed 25 60 !Q:13,13|16,16|18,18|23,23|50,59 Q:0,12|14,15|17,17|19,22|24,49 EEEETTEEEETTS?SS?S?HHHH?HHHHHHHHHTTSSSTTHHHHHHHHTB???--????? 3J0G|M PF01564.12_Spermine_synth_seed 17 352 !Q:5,6|8,8|10,28|47,47|50,50|58,68|72,72|77,88|117,121|123,124|131,131|134,157|170,184|192,192|203,203|210,215|218,218|224,224|228,228|236,236|239,244|252,255|263,267|291,295|299,299|314,314|316,316|325,325|341,344|347,348 Q:0,4|7,7|9,9|29,46|48,49|51,57|69,71|73,76|89,116|122,122|125,130|132,133|158,169|185,191|193,202|204,209|216,217|219,223|225,227|229,235|237,238|245,251|256,262|268,290|296,298|300,313|315,315|317,324|326,340|345,346|349,351 TEEEE??T-T-------------------STTEEEEEEEEEEEEEEE?SS?EEEEEEE-----------SSS?EEEE------------ETTEEEEETTTHHHHHHHHHHHHHTTSS-----S??EEEEEE?TT------------------------SHHHHHHTTSTT?-------------?EEEEEES?HHHHHHHHHH?HHHHGG------GG?TTEEE-EES?HHHHHTT?SS-----?EEEEEEE???-TTTGGGG-----GGSTHHHHHHHHHEEEEEEEEEE?--??TTT?HHHHHHHHHHHHTT?S-EEEEEEEE?TTSGGGEEEEEEEES?---TT??TTS 1UIR|A PF01565.18_FAD_binding_4_seed 142 181 !Q:0,1|3,3|6,8|22,23|26,28|30,33|41,42|45,45|49,58|61,64|69,70|72,73|75,80|87,90|92,94|104,104|117,118|122,127|133,135|145,147|154,156|159,160|170,171|175,175|179,180 Q:2,2|4,5|9,21|24,25|29,29|34,40|43,44|46,48|59,60|65,68|71,71|74,74|81,86|91,91|95,103|105,116|119,121|128,132|136,144|148,153|157,158|161,169|172,174|176,178 ?-S?EE???SHHHHHHHHHHHH--HH---T??--EEEESSS??SS-STT-?------??SS?---EEEE?-T--T-???--EEEEET----T---TTEEEEETT?BHHHHHHHHHHT--TEE????-?TTTTT?--BHHHHHHHT???TTHHHH-??HH--HHEEEEEEE?-TTS?EEE?? 3PM9|A PF01568.16_Molydop_binding_seed 87 143 !Q:3,3|7,8|13,13|18,18|23,23|30,31|33,38|51,53|56,56|66,69|76,77|83,83|85,85|94,95|98,114|116,116|122,126|128,128|132,133|135,135|137,137|139,139|141,141 Q:0,2|4,6|9,12|14,17|19,22|24,29|32,32|39,50|54,55|57,65|70,75|78,82|84,84|86,93|96,97|115,115|117,121|127,127|129,131|134,134|136,136|138,138|140,140|142,142 EEE-EEE?-BTTB?TTSS-SGGG?GGGGSS??S----??EEEEHHHHHHHT-??SS?EEEEEETTE----EEEEEE--EEESS-B?TTEEEEES??TT-----------------S?GGGTS--???B?TTT??B?T-T?E-E 2IV2|X PF01569.16_PAP2_seed 142 268 !Q:11,23|28,31|35,43|53,56|58,62|78,83|89,89|103,103|109,115|121,121|123,123|126,127|129,131|133,133|137,139|154,154|162,162|165,165|169,169|172,195|202,203|206,207|230,231|239,242|252,256|266,266 Q:0,10|24,27|32,34|44,52|57,57|63,77|84,88|90,102|104,108|116,120|122,122|124,125|128,128|132,132|134,136|140,153|155,161|163,164|166,168|170,171|196,201|204,205|208,229|232,238|243,251|257,265|267,267 SHHHHHHHHHH-------------GGGG----HHH---------HHHHHHTTT--?-B??---HHHHHHHHHHHHHTS??????HHHHT?HHHHHHHHHHHHH-HSGGG???????BSSTT?S?SS??S---S?HHH---HHHHHHHHHHHHHH?HHHHTSB?SS?EEE?TT------------------------SSSEEE??SS??BHHHHHHHHHHHHHHHHHHTTS??HHHHHHH----HHHHHHHHH-----HHHHHHHHH?S 2IPB|A PF01570.12_Flavi_propep_seed 9 88 !Q:10,10|17,17|32,33|36,37|49,49|51,51|54,54|56,58|60,60|68,69|78,87 Q:0,9|11,16|18,31|34,35|38,48|50,50|52,53|55,55|59,59|61,67|70,77 EETTEEEEEE?GGGTTS?EEEEETTEEEEEEE??TT??EEEEEEEEEEE?B?SS-S???S?SEEESSS?-EEEEEEEE?????????? 3C5X|C PF01571.16_GCV_T_seed 131 335 !Q:3,3|6,7|15,20|24,25|28,32|42,42|47,50|56,56|62,62|64,64|67,67|81,81|83,94|100,100|123,133|138,138|142,144|154,158|165,167|172,178|180,190|195,195|203,204|206,209|215,215|217,224|228,230|235,236|244,246|249,249|255,258|261,264|281,281|285,285|298,300|306,310|313,313|315,319|322,324|330,330|332,332 Q:0,2|4,5|8,14|21,23|26,27|33,41|43,46|51,55|57,61|63,63|65,66|68,80|82,82|95,99|101,122|134,137|139,141|145,153|159,164|168,171|179,179|191,194|196,202|205,205|210,214|216,216|225,227|231,234|237,243|247,248|250,254|259,260|265,280|282,284|286,297|301,305|311,312|314,314|320,321|325,329|331,331|333,334 EEE?TT--SEEEEEE------STT--HH-----HHHHHHSSS?TTSS?---SSEEE-EEEEE?T-TS?EEEEEEEEEEETT-E------------EEEEE?TTTHHHHHHHHHHHHHHHHTTS?-------???EEEE?TTT---EEEEEEEST-----THHHHH---HHHH-------S?---------?GGGS?TTBEEEE--E----ETTEE-E--------EEE???SSSS-?EEEEEEE???TT?SSGGG????HH----HHHHHHHHHHHHGGGT?EEE?HHHHHHHHHHHT???BTTTB?????SS?S?-?--SS--?TTTTT?G-GG 1WOP|A PF01575.14_MaoC_dehydratas_seed 32 151 !Q:4,7|9,9|11,12|23,23|26,31|36,37|39,39|49,51|56,56|59,59|66,66|68,68|71,73|93,98|102,103|110,110|112,114|117,117|128,129|135,135|148,149 Q:0,3|8,8|10,10|13,22|24,25|32,35|38,38|40,48|52,55|57,58|60,65|67,67|69,70|74,92|99,101|104,109|111,111|115,116|118,127|130,134|136,147|150,150 HHEE----E?S??EEEEEEEESS?SS?-----EEEE??S?THHHHHHHS???HHHH?HH-HHHHTT?S-SS???HHHHHHHHHHHHHHHTSTT-----?TTS??EEEEEE?S???TT?EEEEEEEEEE--EETTE-EEEEEEEEETTT??E 1IQ6|A PF01580.13_FtsK_SpoIIIE_seed 23 302 !Q:13,15|26,26|29,29|39,47|53,54|74,75|85,86|90,90|98,98|104,107|109,109|111,111|132,133|141,141|147,151|164,166|168,168|171,208|210,215|235,242|254,260|262,266|277,296|298,300 Q:0,12|16,25|27,28|30,38|48,52|55,73|76,84|87,89|91,97|99,103|108,108|110,110|112,131|134,140|142,146|152,163|167,167|169,170|209,209|216,234|243,253|261,261|267,276|297,297|301,301 BHHHHHTSHHHHT???TTEEEEEEET-TS?EEEEEGGGS?--------SEEEE??TTSSHHHHHHHHHHHHHTT??TTTEEEEEE??SSS-GGGGGTT?TTBSS----S?B?SHHHHHHHHHHHHHHHHHHH--HHHHHTT?SSHHH-----HHHHHHHHHHTT???B?TT?--------------------------???????????B??-???EEEEEEETHHHHHHHHHHH--------HHHHHHHHHHH------?G-----GGTEEEEEEE--------------------S???T 2IUU|A PF01582.15_TIR_seed 45 175 !Q:5,5|8,17|35,39|41,42|51,52|60,63|71,71|79,79|85,85|87,88|91,91|105,105|107,107|112,113|119,119|125,129|132,132|147,147|151,164 Q:0,4|6,7|18,34|40,40|43,50|53,59|64,70|72,78|80,84|86,86|89,90|92,104|106,106|108,111|114,118|120,124|130,131|133,146|148,150|165,174 EEEEE?HH----------HHTTTHHHHHHHHHHHT-----T??EEEEETTT??GGGTTTT----HHHHHHH?SEEEEEE?TTGGG?H--HH-HHHHHHHHHHHHH?T-TSEE??EEESS?HHHHH-----HT?TTHHHHHHHHTTTS?HHH--------------HHHHHHHHHH 1FYX|A PF01583.15_APS_kinase_seed 20 166 !Q:0,1|8,9|30,32|49,50|75,75|81,85|98,103|107,108|115,117|125,125|139,139|141,141|147,151|154,154|159,159|164,164 Q:2,7|10,29|33,48|51,74|76,80|86,97|104,106|109,114|118,124|126,138|140,140|142,146|152,153|155,158|160,163|165,165 ??EEEEEE??TTSSHHHHHHHHHHHHHHTT-??EEEEEHHHHTTTTTTT??SSHHHHHHHHHHHHHHHHHHHHTT?EEEEE?????HHHHHHHHHHHH------HTT??EEEEEE???HHHHHHH?TTSHHHHHHHTSS?S?BTTTB?????SS?SEEE?TTTS?H 1I2D|A PF01584.14_CheW_seed 247 228 !Q:11,18|33,34|37,38|40,41|45,46|50,55|59,59|65,68|75,75|81,82|84,86|88,102|106,106|113,114|117,133|151,151|156,164|169,171|175,176|182,188|191,196|198,212|217,218 Q:0,10|19,32|35,36|39,39|42,44|47,49|56,58|60,64|69,74|76,80|83,83|87,87|103,105|107,112|115,116|134,150|152,155|165,168|172,174|177,181|189,190|197,197|213,216|219,227 EEEEEEETTEE--------EEEEGGGEEEEEES--TT-?B??TTS?-TTE------EEE-EEETT----EEEEEE?HHHHH??S???T---------------TTS?EEEEEE--ET-----------------TEEEEEEESEEEEEEEE?TTTS????----?SSSS??-GGG??EEEEE-------TT------E---------------EEEE??HHHHHHHHH 2QDL|A PF01588.15_tRNA_bind_seed 43 124 !Q:11,11|14,14|17,18|25,25|30,34|41,41|46,47|54,54|60,62|64,65|67,80|88,89|92,92|96,101|112,112|114,115|118,119|122,122 Q:0,10|12,13|15,16|19,24|26,29|35,40|42,45|48,53|55,59|63,63|66,66|81,87|90,91|93,95|102,111|113,113|116,117|120,121|123,123 EEEEEEEEEEE?TT?SS-?EEEEEE?SSSS?----EEEEES?TTTS?-GGGTTT?EEEEE?-?B??E--------------EETTEEE??EE?EEE------EESSSEEEEE?B??BT??TT?E 2CWP|A PF01589.11_Alpha_E1_glycop_seed 17 538 !Q:0,75|84,84|87,89|95,96|100,101|108,110|124,125|130,133|140,157|161,161|169,171|179,179|181,181|185,185|196,196|203,205|219,220|229,229|231,235|239,240|252,254|256,259|262,262|275,279|282,284|298,301|304,304|307,310|313,316|319,323|326,329|339,339|341,341|346,346|350,350|362,364|373,379|385,388|390,390|397,397|399,399|403,404|411,416|432,432|438,438|440,447|449,449|458,459|479,479|481,482|484,484|488,537 Q:76,83|85,86|90,94|97,99|102,107|111,123|126,129|134,139|158,160|162,168|172,178|180,180|182,184|186,195|197,202|206,218|221,228|230,230|236,238|241,251|255,255|260,261|263,274|280,281|285,297|302,303|305,306|311,312|317,318|324,325|330,338|340,340|342,345|347,349|351,361|365,372|380,384|389,389|391,396|398,398|400,402|405,410|417,431|433,437|439,439|448,448|450,457|460,478|480,480|483,483|485,487 ---------------------------------------------------------------------------?EEEEEEES?TT??-EEEEE??TTB??EEEEEE???EEEEEEEEEEEEE??EEEE????EEETTS??????----------??STT?EEEEESS???EETTEES?S?SSS?EEEEEEEEEE?GGGGTS--?EEEEEEEEEEEEE??EEEETTEE-E?????TTS??EEEETTEEEEE???S????SS?SEEEEETTEEEE?????TT???TTSTTSEEBSSTT---?SS?EE????EE????TT?????EE????HHHHHHHHS?S?HHHH?STT?EEETTTTEEES???SEEEEEEE???????BTTTS????S?EEEEEE?B?SSS??EEEEEE??????EEEEEEESSTTEEES?SEEEE?S--------S?EEEEEEEE??SEEEEEEEETTEEEEEEEE?B??S?SEE?????????????????????????????????????????????????? 3J0F|E PF01590.21_GAF_seed 450 366 !Q:0,1|14,14|18,19|27,28|31,72|85,86|88,90|93,93|100,142|153,183|186,187|191,213|216,220|222,226|228,228|231,234|243,244|248,248|252,253|258,261|263,265|269,275|278,302|313,338|342,345|348,351|356,356 Q:2,13|15,17|20,26|29,30|73,84|87,87|91,92|94,99|143,152|184,185|188,190|214,215|221,221|227,227|229,230|235,242|245,247|249,251|254,257|262,262|266,268|276,277|303,312|339,341|346,347|352,355|357,365 ??HHHHHHHHHHHH-HHH??SEEEEEE??TT------------------------------------------SEEEEEEEEESS??S???TT?EEEGGG?-----------------------------------------?SHHHHHHHHT??----------------------------?EE??GGG????----------------???SS?????S?????S?SS????HHHHHHHH--HTT?SEE--EEEE----E---EET-------TE-------------------------EEEEEEEEES??--------------------????HHH----HH----HHHH-HHHHHHHHH 2Y79|A PF01591.13_6PF2K_seed 11 245 !Q:0,12|19,19|38,41|45,46|61,61|63,72|77,77|80,80|106,108|115,117|134,142|150,153|174,175|179,179|195,199|215,215|224,226|240,245 Q:13,18|20,37|42,44|47,60|62,62|73,76|78,79|81,105|109,114|118,133|143,149|154,173|176,178|180,194|200,214|216,223|227,239 ??-??????????EEEEEE?STTSSHHHHHHHHHHHHH----HTT??EEEEEHHHHHHHHH?S-------???GGGG?TT?HHHHHHHHHHHHHHHHHHHHHHHHS???EEEEES???SHHHHHHHHHHHHHHT--------?EEEEEEE????HHHHHHHHHHHTTTSGGGTT??HHH-HHHHHHHHHHHTTTT?????TTTTTTTSEEEEEET-TTTEEEEE???SHHHHHHHHHHTT?????- 3QPU|A PF01592.11_NifU_N_seed 16 142 !Q:0,2|12,12|17,19|22,22|24,28|37,37|41,42|51,51|54,54|56,56|67,67|75,75|85,86|91,91|94,95|105,113|138,141 Q:3,11|13,16|20,21|23,23|29,36|38,40|43,50|52,53|55,55|57,66|68,74|76,84|87,90|92,93|96,104|114,137 ???HHHHHHHHS?SSBS???TT?S-----SEEEEEEE?TTT??EEEEEEEE?SS-S?EEEEEEEEES?HHHHHHH-HHHHHHHTT??HHHH-HT??HHHHHHHHT-------??GGGGHHHHHHHHHHHHHHHHHHHS???? 1XJS|A PF01593.19_Amino_oxidase_seed 84 727 !Q:13,16|18,32|38,38|44,44|47,50|56,60|68,69|72,76|78,78|81,81|92,93|97,103|105,105|111,112|125,147|161,163|170,170|196,198|236,236|239,240|252,274|305,307|309,309|312,312|326,327|335,336|352,354|357,358|364,364|376,383|386,386|398,410|425,428|437,437|441,443|449,449|452,460|467,469|477,477|483,485|487,487|493,493|496,497|499,499|502,521|525,527|531,544|551,551|556,558|560,564|574,574|579,583|590,590|607,607|609,610|612,612|615,617|619,633|638,639|643,643|650,650|653,653|657,661|671,671|673,676|680,686|689,694|698,698|703,703|708,708 Q:0,12|17,17|33,37|39,43|45,46|51,55|61,67|70,71|77,77|79,80|82,91|94,96|104,104|106,110|113,124|148,160|164,169|171,195|199,235|237,238|241,251|275,304|308,308|310,311|313,325|328,334|337,351|355,356|359,363|365,375|384,385|387,397|411,424|429,436|438,440|444,448|450,451|461,466|470,476|478,482|486,486|488,492|494,495|498,498|500,501|522,524|528,530|545,550|552,555|559,559|565,573|575,578|584,589|591,606|608,608|611,611|613,614|618,618|634,637|640,642|644,649|651,652|654,656|662,670|672,672|677,679|687,688|695,697|699,702|704,707|709,726 HHHHHHHHHHHHT----T?--------------EEEEE?SSSSS?TT??--EEEET-----TEEEESS??EE?---?S-BT?HHHHHHHHTT??EEE???????B?TTSSB??HHHHHHHHHHHH-----------------------HHHHHHHHHHHTS???EETTEE?BHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS?SS??HHHHHHHHHHH-----------------------HHHHHHHHHHHHHHHHHHHHHHHHHHHTTS???S?SS?HHHHHHHHHHHHH--HHHHTTS?-TTTBBTTTTTTTGGG-??BS??EEETT?TTHHHHHHHTT?------?EE?SEEEEEEEEET-------------TEEEEEEEESSSTT---?EEEEEESE-EEE???HHHHH?SS--------?SSEEES???HHHHHHH-HHSEE???E-EEEEE?SS??S?TT?------------------?EEE???SSS--------------TTTTTT?EEEE?--S-----SSSEEEEEE?HHHH-----HHHTTS?HHHHHHHHHHHHHHHH?T--T-TS???S---------------EEEE??TTT?TTTSSS?EE?BTT??---HHHHHHHHS?B????SST-------TS??????EEE?SGGG?TTST-TSHHHHHHHHHHHHHHHH 2V1D|A PF01596.12_Methyltransf_3_seed 8 216 !Q:8,8|24,25|31,32|48,49|55,56|70,70|73,73|81,82|97,97|107,107|113,113|125,125|132,132|134,134|150,150|153,154|159,159|168,169|173,175|195,195|199,200|204,204|208,208|213,213|215,215 Q:0,7|9,23|26,30|33,47|50,54|57,69|71,72|74,80|83,96|98,106|108,112|114,124|126,131|133,133|135,149|151,152|155,158|160,167|170,172|176,194|196,198|201,203|205,207|209,212|214,214 HHHHTSSS?TTHHHHHHHHHHTST--TGGGS??HHHHHHHHHHHHHTT??EEEEE??GGGHHHHHHHHHS?TT?EEEEEES??HHHHHHHHHHHHTT?GGGEEEEES?HHHHH-HHHHHSGGGTT?BSEEEE?S?STTHHHHHHHHHHHB?TT??EEEE?TTGGGGGG??TTS???HHHHHHHHHHHHHHHHHHT?TTB??EEE?STT?EEEE?B? 3OZS|A PF01597.14_GCV_H_seed 14 131 !Q:0,0|3,3|8,11|16,16|20,20|26,26|34,34|41,43|46,46|49,49|52,52|62,62|68,68|71,71|78,78|84,84|91,91|94,94|98,99|105,107|109,109|116,116|119,119|130,130 Q:1,2|4,7|12,15|17,19|21,25|27,33|35,40|44,45|47,48|50,51|53,61|63,67|69,70|72,77|79,83|85,90|92,93|95,97|100,104|108,108|110,115|117,118|120,129 ?EE?TTSE----EEEE?TTS?EEEEE?HHHHHHH?SEEEEE???TT?EE?TT?EEEEEEESS?EEEEE?SS?EEEEEE?THHHH?TTHHHH?TT-TTT??EEEEE---S?GGGGGG-SB?HHHHHHHHHH? 3AB9|A PF01599.14_Ribosomal_S27_seed 12 47 !Q:0,4|8,8|12,12|15,16|18,18|20,21|26,26|34,34|37,37|46,47 Q:5,7|9,11|13,14|17,17|19,19|22,25|27,33|35,36|38,45 ?????SEE?SSS?EE??S?B??STTS?SSSBEEE?SS?EEESSSSS?- 2XZM|9 PF01600.11_Corona_S1_seed 8 587 !Q:0,293|303,314|319,319|322,322|326,326|329,329|333,336|339,339|345,346|357,358|361,362|365,368|371,372|376,377|383,386|390,392|394,399|403,405|416,416|430,430|446,446|451,586 Q:294,302|315,318|320,321|323,325|327,328|330,332|337,338|340,344|347,356|359,360|363,364|369,370|373,375|378,382|387,389|393,393|400,402|406,415|417,429|431,445|447,450 ????????????????????????????????????????????????????????????????????????????????????????????--?????????????????????????????????---??????????????????????????????-----????????????????????????????????????????????????----????????????????????????????-?????????????????????????------?????????????????EEEEEEEEE-----------?EEEE?TS?EEE?TT?EEE????SS?SSEEE??SSEEEEEEEE??EE??TT????SB??TTT??EEEEE??--SSS???S??????EEE---EEEEESSSTT?SEEEEEEEEETTE-EEEEEEEEEEEEEEE-EEEE???---------------------------------------?--------------------------------------?---------------------?------------------------------?? 4F2M|E PF01601.11_Corona_S2_seed 22 730 !Q:0,297|299,299|325,338|393,600|603,612|617,630|644,650|654,729 Q:298,298|300,324|339,392|601,602|613,616|631,643|651,653 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?-----------------------------------------------??--------------??????S?HHHHHHHHHHHHHHHHHHHHHHHHH--------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?????????--------------------------------------------?------------------------------------------------------------------????-----------------------------------------------------?----------------?-------???-??TT?????--???HHHH--------------HHHHHHHHHGGGG???????GGG?--------------------------------------------------------------------------- 1ZV7|A PF01602.15_Adaptin_N_seed 32 891 !Q:17,27|30,30|33,36|54,58|60,64|76,77|94,97|100,104|109,111|120,120|123,126|143,146|151,152|165,165|167,168|170,171|188,193|196,196|201,204|212,213|215,215|218,220|222,243|257,273|284,284|303,303|306,313|316,317|323,323|335,335|337,340|346,346|351,416|418,427|441,455|473,480|483,485|488,495|510,511|524,524|532,541|543,546|552,552|564,564|567,567|582,583|590,592|601,606|608,611|614,615|618,633|650,656|671,674|677,678|682,684|706,707|712,715|722,734|736,736|739,745|747,748|766,768|771,772|774,779|797,797|800,800|805,805|815,825|828,828|830,831|836,847|859,861|863,863|872,880|889,889 Q:0,16|28,29|31,32|37,53|59,59|65,75|78,93|98,99|105,108|112,119|121,122|127,142|147,150|153,164|166,166|169,169|172,187|194,195|197,200|205,211|214,214|216,217|221,221|244,256|274,283|285,302|304,305|314,315|318,322|324,334|336,336|341,345|347,350|417,417|428,440|456,472|481,482|486,487|496,509|512,523|525,531|542,542|547,551|553,563|565,566|568,581|584,589|593,600|607,607|612,613|616,617|634,649|657,670|675,676|679,681|685,705|708,711|716,721|735,735|737,738|746,746|749,765|769,770|773,773|780,796|798,799|801,804|806,814|826,827|829,829|832,835|848,858|862,862|864,871|881,888|890,890 HHHHHHHHHHHTGGGTT-----------TT?ST----TTTTHHHHHHHHHHTTS---??G-----GGSSTTHHHHS-?SSHHHHHHHHHHHHHS????SS-----SSHH---HHHHHHHH-TT---?SSSSHHHHHHHHHHHH?--?SSST--TTTTHHHHHHHH-S??H--HHHHHHHHHHHHHHHH-----?TT?GGGG---?TTTTTST--T?SS---H----------------------HHHHHHHHHHHHH-----------------TSSHHHHHHH-HHSSHHHHHHHHHHHSSS?ST--------TT??SSSSS?HHHHHHHHHHH-H----HHSTT?SHHH------------------------------------------------------------------H----------TTHHHHHHHHHTS-------------??SSHHHHHHHHHHHHHHH--------SS???HH--------HHHHHHHHHHHHHT-?SSTTHHHHHHHH-HHHHHTT----------S----HHHHG-GGHHHHHHHTT-SS?HHHHHHHHHHHHHT??GGGHHH---HHHHHHHH------H----HH??HH----------------HHHHHHHHHHHHHHHS----???HHHHHHHHHHHHHH----TS--TTS--?STHHHHHHHHHHHSSSTHHHH--HHHH----HHHHHH-----------??S?SH-------H--HHHHHHHHHHSTTTTTT???SS--S??????HHHHHHHHHHHHHSTTS?HH-HHHH-HHHHHHHGG-----------GS?S--STHH------------HHHHHHHHGGG--?S?HHHHHHHH---------HHHHHHTT?T 2JKT|A PF01603.15_B56_seed 54 492 !Q:0,17|32,40|44,48|50,50|66,76|78,80|83,84|95,108|111,112|114,118|122,122|126,134|139,141|143,145|162,163|172,172|205,205|222,238|243,247|249,249|251,252|254,254|269,270|273,274|293,293|312,312|327,328|331,331|349,350|369,369|372,372|374,374|387,387|395,399|401,402|419,419|422,423|443,443|450,450|455,460|473,491 Q:18,31|41,43|49,49|51,65|77,77|81,82|85,94|109,110|113,113|119,121|123,125|135,138|142,142|146,161|164,171|173,204|206,221|239,242|248,248|250,250|253,253|255,268|271,272|275,292|294,311|313,326|329,330|332,348|351,368|370,371|373,373|375,386|388,394|400,400|403,418|420,421|424,442|444,449|451,454|461,472 ??-????-??????????TTTHHHHHHHHHHH???-----?SSS?????S-HHHHHHHHHHHHHSS-?--------?S???SS??HHHHHHHHHH????-------???SS??S-----SSS?GGG???---???TTHH---H---HHHHHHHHHHHHTSTT??STTGGGTS?HHHHHHHHHTTTSSTHHHHHHHHHHHHHHHHS?TTTHHHHHHHHHHHHH-----------------HHHH-----T?S??S?HHHHHHHHHHHHSS??SS??HHHHHHHHHTTGGGGGSS?GGGTHHHHHHHHHHHHHH?GGGHHHHHHHHHHT??SS?HHHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHHH-HT?S?HHHHHHHHGGGG?HHHHHHH-----H--TTHHHHHHHHHHHHTS?TT??SSTTHHHHHHHHHHHHHTT?HHHHHH-HHHH------HHHHHHHHHHTS---???????????-???? 3FGA|B PF01607.19_CBM_14_seed 209 96 !Q:2,12|18,24|27,27|29,29|33,33|38,43|49,55|59,59|63,64|69,73|80,80|84,92|95,96 Q:0,1|13,17|25,26|28,28|30,32|34,37|44,48|56,58|60,62|65,68|74,79|81,83|93,94 SS-----------SSEEE??-----SS?S-SEE-EEEE------TTEEE-------EEE?TTS-?EEET-----TTTEEE?TTT---------TT?- 1DQC|A PF01608.12_I_LWEQ_seed 22 167 !Q:35,38|41,46|49,49|73,74|76,76|111,115|118,166 Q:0,34|39,40|47,48|50,72|75,75|77,110|116,117 HHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH----SS?----?HH-HHHHHHHHHHHHHHHHHHHHHTT??S?TTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----HH??????------------------------------------------- 1R0D|A PF01609.16_DDE_Tnp_1_seed 91 375 !Q:7,12|19,20|23,58|67,69|75,75|78,78|81,81|105,105|108,108|112,113|125,139|145,146|148,149|151,151|155,155|166,169|176,179|181,182|187,206|209,210|215,216|221,265|292,293|297,299|308,309|316,320|344,344|346,346|350,354 Q:0,6|13,18|21,22|59,66|70,74|76,77|79,80|82,104|106,107|109,111|114,124|140,144|147,147|150,150|152,154|156,165|170,175|180,180|183,186|207,208|211,214|217,220|266,291|294,296|300,307|310,315|321,343|345,345|347,349|355,374 EEEEEEE------EEETTT??EE------------------------------------EEEEEEEE???SSGGG?SS?GG-GHHHHHHHHHHHHHGGGGGGEEE-EE?GGG??HHHHHHHHHTT--------------?EEEEE??S??B?TTT?SBHHHHHHTS-???EEEEEE----E??EEEE-------------------?SS??EEEE??EEEE---------------------------------------------EEEEEEEEEETGGGEEEEEEEEEEES??SSS???EEEEEESS??SSHHHH-----HHHHHHHHTTHHHHHHHHHHHTT-T?GGG--???SSHHHHHHHHHHHHHHHHHH 1MUS|A PF01611.11_Filo_glycop_seed 6 382 !Q:0,20|33,33|37,38|41,44|61,64|79,81|85,85|90,90|101,101|105,105|109,112|115,118|120,120|131,134|144,144|148,148|156,157|160,160|172,201|216,216|221,222|230,231|233,235|251,253|257,258|263,294|296,298|300,300|303,381 Q:21,32|34,36|39,40|45,60|65,78|82,84|86,89|91,100|102,104|106,108|113,114|119,119|121,130|135,143|145,147|149,155|158,159|161,171|202,215|217,220|223,229|232,232|236,250|254,256|259,262|295,295|299,299|301,302 ----------??????????-EEEEETTEEEEE?SSS??TT????SGGGEEEEEEEGGGGS????HHHHHTTEEEESSS???EEE?SEEE?EEEEEEEEEE?SSS?BSS????TT????S?EEEEEEEEEE????SSEEEETTS?EEE?SSEEESS??TT?EEEEEEEEEEE??????????????????????????????EEEEEEEESSSSSS?EEEE??BTTBEEB??S???HHHHHHHHHHHHHHT???SSS??EEEE??????--------??????????????????S???E-EE????????------------------??????????????????---------?????????????----------??? 3VE0|I PF01612.15_DNA_pol_A_exo1_seed 27 229 !Q:0,0|4,4|21,26|36,37|39,41|43,43|45,45|54,54|56,60|62,62|67,67|71,71|73,84|93,93|103,103|114,120|124,125|132,132|141,142|145,156|166,174|180,180|183,187|191,192|197,204|217,218 Q:1,3|5,20|27,35|38,38|42,42|44,44|46,53|55,55|61,61|63,66|68,70|72,72|85,92|94,102|104,113|121,123|126,131|133,140|143,144|157,165|175,179|181,182|188,190|193,196|205,216|219,228 ?EEE?SHHHHHHHHHHHTTSS------EEEEEEEEE??S?--S-S?EEEEEEEE?S-----S?EEEE?GGG?S?----------?HHHHHHHH?TTSEEEESS?HHHHHHHHHH-------HSS??SSEEEH-HHHHHHTT??TT----------??HHHHHHHHH?---?????TTTTS?TT-----SSS??HHHH--------HHHHHHHHTHHH--HHHHHHHHHH 3SAF|A PF01613.13_Flavin_Reduct_seed 141 392 !Q:3,4|6,6|8,9|15,15|18,24|30,41|43,46|50,52|60,60|62,62|67,67|69,70|72,78|81,160|169,171|173,173|175,186|192,196|199,199|202,202|205,205|208,211|217,241|243,243|245,246|249,249|251,252|256,278|282,289|293,294|297,297|299,299|305,307|312,313|315,320|324,324|326,326|328,339|351,353|356,356|359,359|361,374|376,379|384,384|389,389|391,391 Q:0,2|5,5|7,7|10,14|16,17|25,29|42,42|47,49|53,59|61,61|63,66|68,68|71,71|79,80|161,168|172,172|174,174|187,191|197,198|200,201|203,204|206,207|212,216|242,242|244,244|247,248|250,250|253,255|279,281|290,292|295,296|298,298|300,304|308,311|314,314|321,323|325,325|327,327|340,350|354,355|357,358|360,360|375,375|380,383|385,388|390,390 HTT--S?B??EEEEE-EE-------TTEEE------------E----EEE-??EEEEETT-T-TEEE-E??B-------TT-------------------------------------------------------------------------------?HHHHHHHH---H?E------------EEEEE----?BG-GG-HH-HH----HHHTS-----------------------??S?T--TT-T??EEE?----------------------TTS?-------EEE--TT?S-EEEEE---EEEE--E------EEE-T-T------------EEEEEEEEEEE---EE?TT-S???-----------B---?EEET-TEEE?B? 2D38|A PF01614.13_IclR_seed 23 138 !Q:0,10|28,29|40,47|51,53|69,69|71,71|91,91|93,95|98,98|106,107|112,113|120,122 Q:11,27|30,39|48,50|54,68|70,70|72,90|92,92|96,97|99,105|108,111|114,119|123,137 ???????????EEESSSSHHHHHHHHTS-?HHHHHHHHTT--??????STT???SHHHHHHHHHHHHHH-T?EEEESSSSTTBEEEEEEEE?T---TS?EEEEEEE??BSSS??HHHHHH---HHHHHHHHHHHHHHH 2O9A|A PF01619.13_Pro_dh_seed 15 375 !Q:0,0|17,20|24,24|31,45|71,82|88,88|93,94|104,108|110,111|115,117|138,139|143,146|154,159|166,166|170,170|176,178|207,211|218,219|221,221|234,234|237,237|240,240|252,254|263,263|267,272|279,281|293,293|296,298|300,302|305,305|324,324|329,333|341,342|344,346|362,362|372,372 Q:1,16|21,23|25,30|46,70|83,87|89,92|95,103|109,109|112,114|118,137|140,142|147,153|160,165|167,169|171,175|179,206|212,217|220,220|222,233|235,236|238,239|241,251|255,262|264,266|273,278|282,292|294,295|299,299|303,304|306,323|325,328|334,340|343,343|347,361|363,371|373,374 ?SBSSHHHHHHHHHHHH----TTT?EEEEEE??---------????SHHHHHHHHHHHHHHHHHHHHHHSS?-----------HHHHS?EEEE-?GGGTSTTGG-----G??HHH---HHHHHHHHHHHHHHHHHHHT??EEE????GGGHHHH------HHHHHH-HTT?GGGTT???EEEEEETTBTTHHHHHHHHHHHHHHTTS?----EEEEEE??S?HHHHHHHHHHHT?SS?SB?SSHHHHHHHHH---HHHHHHHT?TTT------EEEEEE???HHHHHHHHHHT?SS?-?G---GG?EEEEETTTSHHHHTTTSS?GGGT?????EEEEEEE??G---GGTHHHHHHHHHHHH?TTSHHHHTT?TT 2G37|A PF01620.11_Pollen_allerg_2_seed 12 200 !Q:0,63|65,65|73,88|106,106|114,115|121,121|135,143|145,145|167,167|189,189|191,192|194,199 Q:64,64|66,72|89,105|107,113|116,120|122,134|144,144|146,166|168,188|190,190|193,193 -------------------------------------------------------------???H-HHHHHHH----------------HHHHHHHHHHHHHTTTS?HHHHHHH--HHHHH-HHHHHHHHHHHHH---------H?TTHHHHHHHHHHHHHHHHHTS?HHHHHHHHHHHHHHHHHHHHT?S??S?????? 1NLX|A PF01624.15_MutS_I_seed 60 150 !Q:0,0|13,13|43,45|49,58|62,64|85,85|87,87|89,90|97,97|99,99|103,120|122,126|128,130|132,133|141,141|145,147 Q:1,12|14,42|46,48|59,61|65,84|86,86|88,88|91,96|98,98|100,102|121,121|127,127|131,131|134,140|142,144|148,149 ?HHHHHHHHHHHT-STTSEEEEEETTEEEEEHHHHHHHHHHHT???EEE?--------?SSS??-EEEEEEEGGGHHHHHHHHHT-T-T??EEEEEE?S?GGG?-----------------S-----S---S??EEEEEEE?TTS???GG 2O8E|A PF01625.16_PMSR_seed 66 195 !Q:6,6|21,28|41,42|44,44|47,49|57,62|64,65|74,74|79,79|88,89|93,93|95,95|111,112|115,116|136,142|148,154|157,163|167,171|182,195 Q:0,5|7,20|29,40|43,43|45,46|50,56|63,63|66,73|75,78|80,87|90,92|94,94|96,110|113,114|117,135|143,147|155,156|164,166|172,181 EEEEEE?SSHHHHHHHHHTST--------TEEEEEEEEESS--S?SS-??HHHHHHT?-----S??EEEEEEEE?TTTS?HHHHHHHH--HHS-S?TTSSSEETTEESGGG??EE??SSHHHHHHHHHHHHHHHHH-------HHHTT???????EE???--??EEE?---?GGGTTHHHHS???--??--????- 3BQE|A PF01627.18_Hpt_seed 241 119 !Q:9,9|27,37|63,64|83,84|88,94 Q:0,8|10,26|38,62|65,82|85,87|95,118 HHHHHHHHH-HHHHHHHHHHHHHHHHH?----------SSSSSHHHHHHHHHHHHHHHHHTTT-?HHHHHHHHHHHHHHHHHH--HTS????---SSHHHHHHHHHHHHHHHHHHHHHT 3KYI|A PF01628.16_HrcA_seed 165 374 !Q:17,17|23,26|30,30|32,33|40,40|42,42|45,45|65,65|67,87|89,94|98,101|110,112|115,120|122,122|131,132|134,134|136,136|139,145|159,179|185,185|192,192|194,194|196,210|222,224|226,226|230,231|236,254|256,258|260,280|290,297|299,300|317,318|320,324|326,352|355,368|370,370 Q:0,16|18,22|27,29|31,31|34,39|41,41|43,44|46,64|66,66|88,88|95,97|102,109|113,114|121,121|123,130|133,133|135,135|137,138|146,158|180,184|186,191|193,193|195,195|211,221|225,225|227,229|232,235|255,255|259,259|281,289|298,298|301,316|319,319|325,325|353,354|369,369|371,373 HHHHHHHHHHHHHHHHT?EEEEE???-GGG?B??EEEEEE?S-SS-EEEEEEEETTEEEEEEEEE?S---------------------S--??-?HHH----HHHHHHHH---HT------T?BHHHHHHT??G-G-GG-------SSHHHHHHHHHHT??-?----------------?SEEEE?HHHHHH?T-T??-------------HHHHHHHHHHT---T?HHH--HHHH?-----------------?S---S---------------------SEEEEGGGG--------S-?GGGTTEEEEEEEEEET--T-----E---------------------------EE--------------E-EEE 1STZ|A PF01630.13_Glyco_hydro_56_seed 11 348 !Q:0,1|4,4|18,18|27,32|35,35|40,41|44,45|47,48|55,55|61,63|66,66|70,74|85,85|101,103|106,107|113,115|118,118|124,125|146,147|188,188|190,197|202,209|226,226|231,231|233,235|244,244|246,246|250,250|267,267|270,272|274,275|278,279|282,282|286,287|289,290|306,306|313,314 Q:2,3|5,17|19,26|33,34|36,39|42,43|46,46|49,54|56,60|64,65|67,69|75,84|86,100|104,105|108,112|116,117|119,123|126,145|148,187|189,189|198,201|210,225|227,230|232,232|236,243|245,245|247,249|251,266|268,269|273,273|276,277|280,281|283,285|288,288|291,305|307,312|315,347 ??SS-SBTTBSSEEEEES?HHHHHHHH??????TT-SSEE??TT??S??SSEEEE?TTSSS???EE?TTS----?EETTSSGGGS?HHHHHHHHHHHHHHH???TT??SEEEE???SS?SSGGG??GGGHHHHHHHHHHHHHHSSS??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTSEEEEBT?S????-???SSTT--??????HHHHHHHHTTHHHHHH?SSBB?B???BGGGTTSS?H-HHH-HHHHHHHHHHHHHHTT?TT-??B??EE?-SB?BTS??B??HHHHHTTHHHHHHTT?SEEEEE??GGGSSSHHHHHHHHHHHHHTHHHHHHHHHHHHH 2J88|A PF01632.14_Ribosomal_L35p_seed 22 63 !Q:0,5|12,12|14,15|19,21|24,25|28,28|31,32|36,36|41,41|47,47|50,51|62,62 Q:6,11|13,13|16,18|22,23|26,27|29,30|33,35|37,40|42,46|48,49|52,61 ??????TTGGGT?B??SSS-??EE??SS?SS??SSS?HHHH-HTTSS?EE??SSSGGGTSSS? 2ZJQ|3 PF01633.15_Choline_kinase_seed 38 396 !Q:0,1|9,37|55,56|68,69|71,74|78,79|102,159|162,163|165,166|176,192|199,202|217,217|230,230|232,246|249,254|259,259|261,262|275,338|340,340|343,343|348,350|353,353|375,375|381,381|384,386|391,392|396,396 Q:2,8|38,54|57,67|70,70|75,77|80,101|160,161|164,164|167,175|193,198|203,216|218,229|231,231|247,248|255,258|260,260|263,274|339,339|341,342|344,347|351,352|354,374|376,380|382,383|387,390|393,395 ??SEEEEEE?????????????????????????????HHHHHHHHHHHHHTTSS??EEEEETTEEEE--E??-?EEE??GGGGGSHHHHHHHHHHHHHHHT???-------------------------------------------------------SS??S??HHHHHHHHH-----------------HHHHHT????SHHHHHHHHHHHTT?HHHHHHHHHHHH-H---------------TS???---EEEE?S??SGGGEEEETTGG----------------------------------------------------------------G?SS?SEEE???TT?EEEEHHHHHHHHHHHTTEETT?SSTTS?EE--?GGGS??HHH- 3FEG|A PF01634.13_HisG_seed 18 215 !Q:1,1|36,39|46,46|48,50|57,57|62,62|64,70|76,85|87,87|93,93|106,131|136,136|139,139|144,145|151,151|161,161|173,174|180,180|182,182|191,195|200,200 Q:0,0|2,35|40,45|47,47|51,56|58,61|63,63|71,75|86,86|88,92|94,105|132,135|137,138|140,143|146,150|152,160|162,172|175,179|181,181|183,190|196,199|201,214 E?GGGHHHHHHTTSSSEEEEEHHHHHHHHHHHHHHT????EEEEEE?S???EEEEEE-EETT-S?-?--??GGGGT----------T?EEEES?HHHHHHHHHHHT-----------------------???EEEE?SS?TTHH--HHTTS?SEEEEEESS?HHHHHTTEEEE--EEEEE-E?EEEEEESS??--?HHHH-HHHHHHHHHHHHHH 2VD3|A PF01636.18_APH_seed 244 701 !Q:4,11|13,14|20,28|31,42|46,52|54,54|56,93|95,95|97,101|105,105|107,118|121,122|127,127|132,149|151,153|155,162|164,166|169,171|178,200|205,206|208,211|213,216|219,226|229,231|241,242|250,285|291,310|313,339|343,343|345,394|398,410|412,412|414,419|421,421|423,444|448,448|452,461|464,464|467,474|478,479|481,489|495,525|533,535|540,552|554,555|559,560|563,564|572,584|589,589|591,592|596,602|605,605|609,609|615,620|623,624|626,627|629,634|637,637|641,641|646,648|652,652|654,654|659,661|670,673|680,691|693,693 Q:0,3|12,12|15,19|29,30|43,45|53,53|55,55|94,94|96,96|102,104|106,106|119,120|123,126|128,131|150,150|154,154|163,163|167,168|172,177|201,204|207,207|212,212|217,218|227,228|232,240|243,249|286,290|311,312|340,342|344,344|395,397|411,411|413,413|420,420|422,422|445,447|449,451|462,463|465,466|475,477|480,480|490,494|526,532|536,539|553,553|556,558|561,562|565,571|585,588|590,590|593,595|603,604|606,608|610,614|621,622|625,625|628,628|635,636|638,640|642,645|649,651|653,653|655,658|662,669|674,679|692,692|694,700 EEEE??-??-??S?-EEEEE--------?SS---?--------EEE-------E-E?----????----------------????---??????H-H-----HHH-H------------HH--HHHT-TSSS----?----------???E---E--------E---EE-??TTTTSS----------------------?EEEE--E????B????TT?-------TT-??HHHHHHHHH--HHHHHHH------------------------------------HHHHS-----------------?--TT---------------------------TTT?T--------------------------------------------------TSS--?---------?S?H------H-H----------------------HHH-HHH----------HH-HH--------HHH??S?-------?HHHHH-------------------------------HHHHGGG???STTS-------------S??EEE-?SS-?SGGGEEE?------------SSSS?E--EEE???----TT?EEE?HHHHH------HH--H--G------GG-GTS?SSSS???TTS?H-HHHT???HHHHHHHH----HHHHSS---------???S?HHHHHHH 3FEG|A PF01637.13_Arch_ATPase_seed 56 325 !Q:1,1|3,3|17,19|26,27|44,46|62,62|64,64|73,94|99,99|105,131|137,145|151,151|154,154|156,157|173,173|175,175|193,208|224,228|235,236|242,245|254,254|257,257|265,267|272,276|293,302|307,307|317,317 Q:0,0|2,2|4,16|20,25|28,43|47,61|63,63|65,72|95,98|100,104|132,136|146,150|152,153|155,155|158,172|174,174|176,192|209,223|229,234|237,241|246,253|255,256|258,264|268,271|277,292|303,306|308,316|318,324 S?S?HHHHHHHHHHHHH--?SEEEEE??TTSSHHHHHHHHHHHS---SEEEEEHHHHHHTTT?B?HHHHHHHH----------------------HHHS?SHHHH---------------------------HHHHT----?????GGGTS?GG-G??HHHHHHHHHHHHHHH-S?EEEEEETGGGGGGBTTT----------------TTHHHHHHHHHHHHH----?TTEEEE--EEESS----HHHHHHHH?TT?TTSTTTT???EEEE?????HHHHHHHHHHHHHTTT--?----???HHHH-HHHHHHHTT?HHHHHHH 1L8Q|A PF01638.12_HxlR_seed 14 92 !Q:2,2|16,18|20,20|28,28|32,32|55,55|59,59|66,66|89,91 Q:0,1|3,15|19,19|21,27|29,31|33,54|56,58|60,65|67,88 HH?STTHHHHHHHHTT-??B?HHHHHHH?TTS?HHHHHHHHHHHHHTTSEEEEEE?SSS?EEEEEE?TTGGGGHHHHHHHHHHHHHHHT??? 4HQM|A PF01640.12_Peptidase_C10_seed 53 272 !Q:0,1|7,7|11,11|13,15|17,18|22,24|29,32|47,48|51,60|62,62|66,67|70,71|75,75|78,78|83,83|85,89|92,92|94,95|100,100|103,104|106,115|117,117|122,122|138,138|140,140|144,148|150,152|156,156|166,166|168,168|171,172|176,177|183,183|198,199|201,202|213,217|227,246|251,251|253,255|259,259|265,265|267,267|271,271 Q:2,6|8,10|12,12|16,16|19,21|25,28|33,46|49,50|61,61|63,65|68,69|72,74|76,77|79,82|84,84|90,91|93,93|96,99|101,102|105,105|116,116|118,121|123,137|139,139|141,143|149,149|153,155|157,165|167,167|169,170|173,175|178,182|184,197|200,200|203,212|218,226|247,250|252,252|256,258|260,264|266,266|268,270 ??SSTTT?TTS?B??-S??TTS???TTSB????HHHHHHHHHHHHHT??SB------????E-EEE??TT?-TTS?SS?EEEE?G-----GG?B??TTTS?SB??S---------?S?HHHH-HHHHHHHHHHHHHTT?B?SSS----?B???HHH-HHHHHHHTT?B?TT-?EEE--EGGGS?HHHHHHHHHHHHHT--T??EEEEEEETTE-----EEEEEEEEE--------------------ESSS?E---EEE?SSTTT-T?EEE? 4D8B|A PF01641.13_SelR_seed 18 130 !Q:8,8|20,20|24,24|26,32|34,34|53,54|58,59|64,65|67,67|71,71|74,77|83,83|102,103|108,111|113,114|120,120|128,128 Q:0,7|9,19|21,23|25,25|33,33|35,52|55,57|60,63|66,66|68,70|72,73|78,82|84,101|104,107|112,112|115,119|121,127|129,129 TTGGGTTS?TTHHHHHHHTT?SSS?S???????S?SEEEETTTTEEEEEGGGS??STT??SEES??S?TTS-EE????BTTSS?EEEEEETTEEEEEEEEEE-?SSSS----S-?EEEEE?STTEEEE?S 3MAO|A PF01642.17_MM_CoA_mutase_seed 11 561 !Q:2,2|6,6|9,9|12,15|22,26|29,30|36,36|39,39|48,50|53,54|57,58|76,77|82,82|84,84|91,92|108,110|123,123|127,127|129,132|136,137|157,158|162,162|167,170|178,181|183,183|202,202|207,207|212,212|220,221|245,246|261,261|263,263|285,285|287,290|297,299|305,305|309,310|333,333|338,340|346,347|350,354|373,374|384,384|410,426|457,458|465,466|469,482|502,502|520,521|524,524|528,531|544,545|558,560 Q:0,1|3,5|7,8|10,11|16,21|27,28|31,35|37,38|40,47|51,52|55,56|59,75|78,81|83,83|85,90|93,107|111,122|124,126|128,128|133,135|138,156|159,161|163,166|171,177|182,182|184,201|203,206|208,211|213,219|222,244|247,260|262,262|264,284|286,286|291,296|300,304|306,308|311,332|334,337|341,345|348,349|355,372|375,383|385,409|427,456|459,464|467,468|483,501|503,519|522,523|525,527|532,543|546,557 EE?TTS?EE?SB??--GGGGTT???--TT??TTSTT?TT?SSSSGGGT???EE??EE??BSHHHHHHHHHHHHHTT??SEEE?B?HHHHTT??TTSGGGTTTTTTSSB???SHHHHHHHTTTS?TTT?E----EEE??STTHHHHHHHHHHHHHHTT??GGG?EEEE????HHHHHTT????S?HHHHHHHHHHHHHHHHHH?TTEE?EEEE?HHHHHHT??HHHHHHHHHHHHHHHHHHHHHTT??GGGTGGGEEEEEEE?S?HHHHHHHHHHHHHHHHHHHHT-T?--?SSGGGG???EEEEE?STT??SSSTTHHHHHHHHHHHHHHHTT?SEEE???TTTTT--SS?---?HHHHHHHHHHHHHHHHTS??SSSSSTTTT?HHHHHHHHHHHHHHHHHHHHHHHTT----------------?HHHHHHHTHHHHHHHHHHHHHHHHHHHTSS??BTTTBS??SS?????--??--???HHHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHHS??TT?GGG---?HHHHHHHHHHTT??HHHHHHHHHHHH??? 5REQ|A PF01643.12_Acyl-ACP_TE_seed 27 297 !Q:1,2|9,10|15,15|21,21|42,43|47,52|72,73|77,77|89,89|92,92|101,102|105,106|123,123|127,129|137,148|150,150|153,153|156,168|171,171|178,179|184,184|190,190|202,202|204,204|221,221|223,225|228,228|238,261|277,283|297,297 Q:0,0|3,8|11,14|16,20|22,41|44,46|53,71|74,76|78,88|90,91|93,100|103,104|107,122|124,126|130,136|149,149|151,152|154,155|169,170|172,177|180,183|185,189|191,201|203,203|205,220|222,222|226,227|229,237|262,276|284,296 S??EEEEEE??GGGB?TTSBB?HHHHHHHHHHHHHHHHHHTT??HHH------HHTTTEEEEEEEEEEEESS??BTT?EEEEEEEEEEE?SS?EEEEEEEE?-TT??EEEEEEEEEEEEETTT?SEE???GGGTGGG------------T?EE?SS?????????????TT?EEEEEE??GGGB?TTSSB?GGGHHHHHHHH-S?HHHHHTEEEEEEEEEE?S???TT?EEEEEEEEE----------------------??SSTTEEEEEEEEEET-------TEEEEEEEEEEEE- 2ESS|A PF01645.12_Glu_synthase_seed 15 430 !Q:0,0|2,3|17,30|42,46|55,56|59,73|78,79|89,91|93,93|98,98|114,115|117,117|120,120|123,125|131,136|140,141|147,148|150,151|154,158|164,164|167,167|170,184|191,191|198,200|203,203|207,208|211,211|215,216|226,226|229,230|233,234|237,237|240,240|257,258|269,270|280,283|289,289|296,296|299,301|313,315|332,332|336,336|344,345|358,358|363,363|373,378|383,384|390,392|397,398|401,404|428,428 Q:1,1|4,16|31,41|47,54|57,58|74,77|80,88|92,92|94,97|99,113|116,116|118,119|121,122|126,130|137,139|142,146|149,149|152,153|159,163|165,166|168,169|185,190|192,197|201,202|204,206|209,210|212,214|217,225|227,228|231,232|235,236|238,239|241,256|259,268|271,279|284,288|290,295|297,298|302,312|316,331|333,335|337,343|346,357|359,362|364,372|379,382|385,389|393,396|399,400|405,427|429,429 ?S??HHHHHHHHHHHHH??????????????HHHHHHHHHHS?-???SGGGGEEE??SS??-----------??TTTS??HHHHHTTEE???B?TTTS?HHHHHHHHHHHHHHT-?B?EE?SS???GGGSS??????TTS??SSSTT??S??TT?????SEEEE?TT?TT??-------------HHHHHS?SEEEEE???TT?TTS??EE?GGG??HHHHHHHTS?TT??EE??SS?TT?SSHHHHHHHHHHHHHH?-TTSEEEEEEE??TTHHHHHHH----HHHTT?SEEEEE?TT???SSEEHHHHHHB???HHHHHHHHHHHHHHTT?GGG?EEEEESS??SHHHHHHHHHHT?SEEE?SHHHHHHHT??????GGGT??TTSSS???HHHH--HT????HHHHHHHHHHHHHHHHHHHHHHT?S 2OZ0|A PF01648.15_ACPS_seed 154 248 !Q:9,13|19,43|52,53|59,59|61,64|74,74|76,110|132,132|134,134|136,152|154,158|167,184|188,188|194,194|197,216|226,227|231,233|239,239 Q:0,8|14,18|44,51|54,58|60,60|65,73|75,75|111,131|133,133|135,135|153,153|159,166|185,187|189,193|195,196|217,225|228,230|234,238|240,247 EEEEEEEEH-----HHHHH-------------------------HHHHHHHH--HHHHH-S---?HHHHHHHHH?S?----------------------------------HHHHHHHHHHHHHHHHHHTTS?S?T-----------------T---??GGGEEEEE?-----------------TTS?EEEEE?HH--------------------HHHHHHHTT??EEE---EEEEE?SSEEEEEE 3NE1|A PF01649.13_Ribosomal_S20p_seed 14 91 !Q:0,2|40,41|44,50|73,73 Q:3,39|42,43|51,72|74,90 ???SGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT??HH-------HHHHHHHHHHHHHHHHHHTSTT?HHHHHHHHHHHHHHTTT 3KIX|t PF01650.13_Peptidase_C13_seed 34 357 !Q:7,9|30,30|33,34|42,46|50,50|53,53|58,59|65,76|78,79|82,85|88,88|92,93|104,104|114,120|123,123|132,132|137,139|143,143|145,148|169,170|189,192|204,204|208,209|215,228|251,251|253,253|257,259|272,280|283,284|289,289|300,300|302,353|356,356 Q:0,6|10,29|31,32|35,41|47,49|51,52|54,57|60,64|77,77|80,81|86,87|89,91|94,103|105,113|121,122|124,131|133,136|140,142|144,144|149,168|171,188|193,203|205,207|210,214|229,250|252,252|254,256|260,271|281,282|285,288|290,299|301,301|354,355 EEEEEEE???SGGGHHHHHHHHHHHHHHHH-TT??GGGEEEE????-STT?TT?SSTT??BSSTT-----?-----?B??TT-???SB?GGG??HHHHHHHHHT?TGGGTTSTT???????TT?EEEEEEES?EETT---EEE?S----SSEEEHHHHHHHHHHHHHTT??SEEEEEEESTTGGGGTTT--??TTSSEEEEESS?TTS??BEEEE--------------ETTTTEEEEEHHHHHHHHHHHH-S?TTT--?BHHHHHHHHHHH?-------?SS??EEEE?GGGGGSBTHH-H----------------------------------------------------HS? 4FGU|A PF01652.13_IF4E_seed 135 358 !Q:11,19|21,22|24,46|49,49|58,71|88,89|91,91|95,95|101,115|122,124|126,126|136,136|141,142|146,172|176,197|219,219|224,242|250,253|256,260|262,262|264,264|267,281|286,286|289,289|291,311|313,313|326,327|331,332|334,335|338,352 Q:0,10|20,20|23,23|47,48|50,57|72,87|90,90|92,94|96,100|116,121|125,125|127,135|137,140|143,145|173,175|198,218|220,223|243,249|254,255|261,261|263,263|265,266|282,285|287,288|290,290|312,312|314,325|328,330|333,333|336,337|353,357 EEEEEEEEEEE---------E??T-----------------------TS?HHHHEEEE--------------EEEEEHHHHHHHHHHS??G-GGS?TTEEE---------------EEEETT?-?S-STTSTTTTT?EEEE--EEE?--------------------------HHH----------------------HHHTHHHHHHHHHHHHHTTTT-GGGG-------------------GGEEEEE----EE-??--T-T?EE---------------EEEE-ES?T---------------------T?HHHHHHHHHHHH--HHH--T??TT??--------?----EEEEH 3U7X|A PF01653.13_DNA_ligase_aden_seed 15 333 !Q:0,1|25,25|29,30|47,47|51,52|59,60|62,66|68,70|74,74|77,81|85,85|97,100|108,114|140,141|150,150|157,157|161,161|164,165|169,174|185,186|202,205|207,207|218,218|220,220|228,229|243,246|261,265|268,268|273,275|297,297|315,315|317,317|329,332 Q:2,24|26,28|31,46|48,50|53,58|61,61|67,67|71,73|75,76|82,84|86,96|101,107|115,139|142,149|151,156|158,160|162,163|166,168|175,184|187,201|206,206|208,217|219,219|221,227|230,242|247,260|266,267|269,272|276,296|298,314|316,316|318,328 ??HHHHHHHHHHHHHHHHHHHHHTT?SSB??THHHHHHHHHHHHHHH?TTS??TTSGGG??S-????B???EEE?SS?????EEE?SHHHHHHHHHH----HHHHSSS???--??EEEEEEESSEEEEEEEETTEEEEEE??TTSSEEEB?HHHHHT?TTS?SB??SSS----??SEEEEEEEEE??HHHHHHHHHHHHHSS????S?HHHHHHHHHT?S?HHHHHTS??EEEEEEEEEEESS???-SBHHHHHHHHHHHT??-??TT?EEES---SHHHHHHHHHHHHHHGGGSSS?EEEEEEEESBHHHHHHH?B?SSSBSSEEEEE???? 3BA8|A PF01655.13_Ribosomal_L32e_seed 75 124 !Q:0,6|12,12|14,14|17,28|31,31|35,39|41,46|48,48|52,54|57,123 Q:7,11|13,13|15,16|29,30|32,34|40,40|47,47|49,51|55,56 ???????TTTTT?T-TS??--???????-SS?TTT?????S??---?S?TTS???TT???????--????????????????----????????????????????????-????????????? 1S1I|0 PF01656.18_CbiA_seed 79 361 !Q:3,4|7,8|25,26|29,30|36,38|41,41|49,51|53,54|56,78|84,84|86,98|103,103|107,141|148,150|154,185|195,203|211,213|215,217|219,219|226,227|230,231|234,249|257,257|269,270|273,274|293,298|301,301|312,312|315,317|325,325|329,329|337,338|340,340|342,352|354,355 Q:0,2|5,6|9,24|27,28|31,35|39,40|42,48|52,52|55,55|79,83|85,85|99,102|104,106|142,147|151,153|186,194|204,210|214,214|218,218|220,225|228,229|232,233|250,256|258,268|271,272|275,292|299,300|302,311|313,314|318,324|326,328|330,336|339,339|341,341|353,353|356,360 EEE??SS??HHHHHHHHHHHHHHHH--TT??EEEEE?-?TT?HHHHHTT???S??H-----------------------HHHHT-T?-----------?GGGT?EEE-----------------------------------TTEEEE???TTH--------------------------------HHHHHHHTT--------?TTHHHHH???T---T?SEEEEE??SS??HH----------------HHHHHHH?SEEEEEEESST--HH--HHHHHHHHHHHHHHHHHT?-----TT?EEEEEEEESB?TT--?SHHHHHH-HHH-HHHHGGG--B?S--------???B??HHHHH 1XCP|A PF01657.12_Stress-antifung_seed 175 180 !Q:4,8|12,19|22,22|24,24|26,26|40,41|50,61|67,78|82,88|96,96|98,98|100,100|102,110|112,115|118,119|124,124|134,137|141,146|149,152|160,164|168,168|175,175|178,179 Q:0,3|9,11|20,21|23,23|25,25|27,39|42,49|62,66|79,81|89,95|97,97|99,99|101,101|111,111|116,117|120,123|125,133|138,140|147,148|153,159|165,167|169,174|176,177 EEEE?----SSB--??----TT?T-H-HHHHHHHHHHHHH--HGGGTTSE------------EEEEE------?----?STT??----?EEEEEEE?T-T-S----?----H----HH--HHHH-HHHHHTTHH----HHT------TS----BSSEEEE-----ETT-EEEEEE-SS?? 3A2E|A PF01658.12_Inos-1-P_synth_seed 60 161 !Q:17,17|29,29|37,56|59,60|62,62|67,109|115,117|122,123|126,126|143,143|147,147 Q:0,16|18,28|30,36|57,58|61,61|63,66|110,114|118,121|124,125|127,142|144,146|148,160 HHHHHHHHHHHHHHHTT?EEEEEEEEEEE?SHHHHHT????????????????????TT--T?TTTS-------------------------------------------BTTTB???EEEE??EE?GGGTTEEEEEEEEEEE?GGG?EEEEEEEEEEEHH 3QW2|A PF01661.16_Macro_seed 124 178 !Q:4,4|7,7|9,15|18,18|28,29|37,37|41,46|48,56|59,59|65,65|70,75|83,84|86,91|94,98|117,124|126,127|132,154|159,160|167,169 Q:0,3|5,6|8,8|16,17|19,27|30,36|38,40|47,47|57,58|60,64|66,69|76,82|85,85|92,93|99,116|125,125|128,131|155,158|161,166|170,177 EEEE?TT?S?-----?SH-HHHHHHHHH?-HHHHHHH-TTT------T?------??BT?EEEEE?TTSS------SSEEEEE--E?--???SS?---?TTTHHHHHHHHHHHHHHH--------H--HHTT??---------------------EEEE??TTSSTT???HHHHHHHH 2AFC|A PF01663.17_Phosphodiest_seed 70 701 !Q:8,9|18,24|27,27|34,42|51,52|55,56|59,60|71,73|79,81|87,129|136,137|139,139|145,146|149,149|153,161|163,164|171,171|175,186|189,189|192,192|198,198|203,224|227,233|236,238|240,240|242,295|305,305|310,311|315,324|332,336|343,343|345,366|369,369|371,372|374,375|379,386|390,395|416,416|420,420|423,423|427,436|438,440|443,478|485,495|500,510|512,512|514,515|519,531|534,534|538,538|544,565|575,575|586,594|598,598|605,607|610,612|615,616|620,647|649,649|653,653|660,660|663,663|671,685|689,691|697,698|700,700 Q:0,7|10,17|25,26|28,33|43,50|53,54|57,58|61,70|74,78|82,86|130,135|138,138|140,144|147,148|150,152|162,162|165,170|172,174|187,188|190,191|193,197|199,202|225,226|234,235|239,239|241,241|296,304|306,309|312,314|325,331|337,342|344,344|367,368|370,370|373,373|376,378|387,389|396,415|417,419|421,422|424,426|437,437|441,442|479,484|496,499|511,511|513,513|516,518|532,533|535,537|539,543|566,574|576,585|595,597|599,604|608,609|613,614|617,619|648,648|650,652|654,659|661,662|664,670|686,688|692,696|699,699 EEEEEETT??HHHHHHSG-------GG?HHHHHH---------HHTSEEES?-EE??SS??HHHHHHHHHH???HHHHS???SSEEE-------------------------------------------TTTTEE--E?SSSGG--GG?TTT?-------?S??HHHHHH-HTT??----------EE?SS?TTSSS?BTTB?--------------------?SB?--????TT---S?H------------------------------------------------------HHHHHHHHH-HTTS-?TTT?--------?SEEEEEE----?TTHHHH-H----------------------HH?S--S--SHH--------HHH------HHHHHHHHHHHHHHHHHHTT?TTS?EE-EEE?---------S???EE?----------------------------------?SSSEEE-----------THHH-----------H?S??SEE-------------EE?BSS?EEEES----------------------STTTSTTTS?HHHHHHHHSS?--------STT?SEEEEE---GG---GS?-GGG???-------------------------S?SSS?SEEEEE?TT?EEESSTT---------------TSS?--SSSEE??S? 4GTW|A PF01664.11_Reo_sigma1_seed 3 221 !Q:0,16|19,19|22,22|35,36|38,38|54,58|61,61|76,76|81,81|119,120|125,127|139,139|141,141|144,145|150,151|153,157|159,159|171,171|199,199|201,204|210,211|218,220 Q:17,18|20,21|23,34|37,37|39,53|59,60|62,75|77,80|82,118|121,124|128,138|140,140|142,143|146,149|152,152|158,158|160,170|172,198|200,200|205,209|212,217 ---??????????????EE?TT?EEEEETTEEEEE??B?TTTEEEETTEEEESS?????EE?TTEEEETTTTEEEE?HHHH?EEEEEEEEEEEEETTEEEEEEEEEEEEEETTEEEEEE??EEEE???SSEEEEEETTS?B?TT??GGGG??S??--?S?SEEEEEEEEEE?SSSEEEEEEEEEEEEEETTEEEEEEEE?S????SEEEE??EEEEEE??? 3S6Y|A PF01665.11_Rota_NSP3_seed 6 335 !Q:0,2|30,33|37,37|73,73|86,86|104,109|120,120|124,125|128,128|131,131|134,156|158,159|170,172|184,334 Q:3,29|34,36|38,72|74,85|87,103|110,119|121,123|126,127|129,130|132,133|157,157|160,169|173,183 ???HHHHHHHHHHHHHHHHHHHHHHHHHTT????HHH-HHHHHHHHHHHHHHHTSTTHHHHHHHHHHHHHHTT?THHHHHHHHHHH?TTHHHHHHHHHHHHHHH??????HHHHHHHHHH?EEE??TT?SS?EE-----------------------E??HHHHHHHTTS?--EEEEHHHHHHT?-----------------------------------------------------------------------------------------------------------------------------------------------------? 1KNZ|A PF01667.12_Ribosomal_S27e_seed 7 55 !Q:0,3|8,9|13,13|15,15|22,22|25,28|32,34|36,36|38,39|43,43|45,46|49,54 Q:4,7|10,12|14,14|16,21|23,24|29,31|35,35|37,37|40,42|44,44|47,48 ????EEEE??TTS?S?EEEESB?SS????SSS???S?B??SSB?B??SS?????? 2XZM|6 PF01668.13_SmpB_seed 166 80 !Q:0,0|5,6|9,9|17,17|24,25|27,29|39,41|44,44|47,48|51,53|56,61|64,66|69,72|74,79 Q:1,4|7,8|10,16|18,23|26,26|30,38|42,43|45,46|49,50|54,55|62,63|67,68|73,73 ?EEEE--EE?STTTTTS?EEEEEE??B???HHHHHHHHS???EE?TT??EE?-?SS----??EE???EE???-S?????? 1ZC8|K PF01670.11_Glyco_hydro_12_seed 12 180 !Q:2,5|11,11|25,25|28,29|44,44|47,48|51,51|59,59|64,66|95,98|112,113|136,136|138,138|140,142|149,149|155,156|158,159|162,163 Q:0,1|6,10|12,24|26,27|30,43|45,46|49,50|52,58|60,63|67,94|99,111|114,135|137,137|139,139|143,148|150,154|157,157|160,161|164,179 TT????EEGGG?SEEEEEEEEEEEE?TT??EEEEEEEEEESSTT?SS??TT?EEEEEEE-EEES???SSEEEEEEEEEEEETTEEEEEEEEEEEE----ESSSEEEEEEESS??SEEEEEEEHHHHHHHHHHHHTT?S-S???GGGSEE?EEEEE??B??TT??EEEEEEEEEEEEEEEE 1W2U|A PF01674.13_Lipase_2_seed 15 288 !Q:0,2|7,8|11,21|37,39|46,48|50,50|53,55|62,69|71,73|86,87|89,89|110,111|115,126|137,152|157,157|160,174|176,187|189,221|223,225|228,232|240,240|244,251|254,256|259,260|268,268|270,270|272,273|276,278|283,283 Q:3,6|9,10|22,36|40,45|49,49|51,52|56,61|70,70|74,85|88,88|90,109|112,114|127,136|153,156|158,159|175,175|188,188|222,222|226,227|233,239|241,243|252,253|257,258|261,267|269,269|271,271|274,275|279,282|284,287 ???EEEE??TT--------?-?GGGGHHHHHHHHHTT-??GGGEEE???S?TT?-?HHHHHH--------H---HHHHHHHHHHHH??S?EEEEEETHHHHHHHHHHHHS--SGG------------GTEEEEEEES--------------??GGGT?SB????-----------S-----?------T---------------------------------T???EE-----EEEEETT?SSS-------?HH---HH??BTSEEEE-E?S??TG---GGGG?HHHH 1CVL|A PF01676.13_Metalloenzyme_seed 27 567 !Q:0,1|10,13|15,16|18,20|22,22|25,26|30,40|51,51|54,55|59,59|67,68|71,74|87,90|103,103|107,107|122,123|133,134|137,138|154,154|156,156|164,164|167,168|171,171|174,174|185,185|192,198|210,213|215,216|230,231|233,234|239,239|252,254|258,260|265,265|269,269|272,275|278,278|283,286|299,299|302,303|305,305|307,309|312,314|316,316|323,325|329,329|335,342|344,344|354,355|376,377|379,382|391,393|395,395|401,401|421,423|425,425|432,432|436,436|443,443|457,457|471,471|477,477|479,479|484,484|487,487|491,503|505,506|508,508|510,512|518,519|521,534|536,537|539,539|542,542|557,560|563,566 Q:2,9|14,14|17,17|21,21|23,24|27,29|41,50|52,53|56,58|60,66|69,70|75,86|91,102|104,106|108,121|124,132|135,136|139,153|155,155|157,163|165,166|169,170|172,173|175,184|186,191|199,209|214,214|217,229|232,232|235,238|240,251|255,257|261,264|266,268|270,271|276,277|279,282|287,298|300,301|304,304|306,306|310,311|315,315|317,322|326,328|330,334|343,343|345,353|356,375|378,378|383,390|394,394|396,400|402,420|424,424|426,431|433,435|437,442|444,456|458,470|472,476|478,478|480,483|485,486|488,490|504,504|507,507|509,509|513,517|520,520|535,535|538,538|540,541|543,556|561,562 ??EEEEEETB????S??T---T?HH--HHS??---------HHHHHHHHHS?EE--EEB?SGGGGTS?-TT????HHHHHHHHHHTS????HHHHHHHHHHTT?GGG?HHHHHHHHHHHHTT??EEEEEEESS??SS??HHHHHHHHHHHHHTT?S?EEEEEEE?SS--SS?TT?HHHHHHHHHH-HHHHHT?----??EEEEEEHHHHT?--?S??HHHHHHHHHHHHH??S?-EESS-HHHHHHHHHHTT-??GGG???EEEB?TTS?BS????TT?EEEE????STTTHHHHHHHH?SS??S-S???TT???S?EEEEEE???SSS?SEEEE--??????S?HHHHHHHTT??EEEEEEGGGHHHHTTTTTTS??S?--?TTEEEEEE???S?SSGGG?TTTTHHHHHHHHHHHHHHT??-S-EEEEEE?HHH-HHHTTT?HHHHHHHHHHHHH-HHHHHHHHHHHTT?EEEEE?S?BSTT?SB?TTS------------?B??S?B???EEEEE??T--------------T??B?SS?BGGGHHHHHHHHTT????TT???? 1KHL|A PF01678.14_DAP_epimerase_seed 28 154 !Q:8,8|15,15|18,22|24,31|40,40|45,47|65,65|68,69|72,73|87,87|89,90|93,93|96,96|110,117|124,124|127,128|137,137|147,150 Q:0,7|9,14|16,17|23,23|32,39|41,44|48,64|66,67|70,71|74,86|88,88|91,92|94,95|97,109|118,123|125,126|129,136|138,146|151,153 EEEEESSS?EEEEEE?TT?---?S???-----HHHHHHHH?TTTS???SEEEEEEEHHHHHHTTS?SS??TT??TTSEEEEEEETTS?B??TT?TT-HHHHHHHHHHTTS?-----??SEEEEE?TT??EEEEEEEE?SSEEEEEEE????EEE 2Q9J|A PF01680.12_SOR_SNZ_seed 10 211 !Q:2,2|16,16|35,35|41,41|44,44|53,56|58,59|70,70|73,73|82,82|94,94|104,105|107,107|110,113|117,117|120,120|139,139|145,147|151,152|174,175|188,189|191,191|203,203|210,210 Q:0,1|3,15|17,34|36,40|42,43|45,52|57,57|60,69|71,72|74,81|83,93|95,103|106,106|108,109|114,116|118,119|121,138|140,144|148,150|153,173|176,187|190,190|192,202|204,209 ES?HHHHHHHHHTTTT?EEEEESSHHHHHHHHHHT?SEEEE?SS?HHHHHHTT????S??HHHHHHHHHH?SS?EEEEEETT?HHHHHHHHHTT?SEEEEETTS??S?SS????GGG?SS?EEEEESSHHHHHHHHHTT?SEEEE???TTT??THHHHHHHHHHHHHHHHHHHS-?GGGHHHHHHHHT??H-HHHHHHHHHTS?SSEEEB? 3O05|A PF01686.12_Adeno_Penton_B_seed 19 562 !Q:0,12|18,18|20,21|25,26|28,28|31,34|36,36|50,51|59,62|66,66|69,70|73,74|77,78|83,86|94,96|99,99|104,104|109,110|115,130|134,137|141,142|146,147|150,151|177,178|182,184|186,188|190,190|196,196|200,200|207,210|212,216|219,219|222,223|225,226|229,229|241,241|246,248|250,250|254,255|257,257|261,261|264,264|272,353|357,357|359,363|366,370|373,373|376,376|378,381|387,387|393,393|397,402|414,417|420,423|429,429|434,436|439,445|449,450|457,457|464,466|481,481|484,484|487,487|489,489|492,492|497,501|504,504|510,515|517,520|522,522|526,526|535,535|540,541|551,556|559,561 Q:13,17|19,19|22,24|27,27|29,30|35,35|37,49|52,58|63,65|67,68|71,72|75,76|79,82|87,93|97,98|100,103|105,108|111,114|131,133|138,140|143,145|148,149|152,176|179,181|185,185|189,189|191,195|197,199|201,206|211,211|217,218|220,221|224,224|227,228|230,240|242,245|249,249|251,253|256,256|258,260|262,263|265,271|354,356|358,358|364,365|371,372|374,375|377,377|382,386|388,392|394,396|403,413|418,419|424,428|430,433|437,438|446,448|451,456|458,463|467,480|482,483|485,486|488,488|490,491|493,496|502,503|505,509|516,516|521,521|523,525|527,534|536,539|542,550|557,558 ?????????????SSSTT?B??SSS??B?SS????B?STTTTTTTTSSSS??SSEEEEE????SSS?SS??SS??EE??SSEE????BEEEEEE???SS?TTTT?SEEE??EEEE???------------?SSS????EEE??EEE??SS??SHHHHHHHHHHHHHHHHTTTHHHHS??SSS???B???B?TTSSB?TTT?SBTTSS????B?????BB?TT??B??TT?SHHHHHTEEES?TTSS???B?STT??S?EEE?BB?HHHHHHH???????????????????????????????????????????-??????????????????????????????????????STT?B-????TT?????BS?SS?S----EEEEE?SHHHH-SSS?-----TTTSGGGTEEE????TT????EEEEE?TTTB???TT????-??TTS??EEEEEE?SEEEEE???TTTTTTHHHHHHHS-SS?SS?S?SS?SSSS?????SS?EEEEE??????B????B?SEE?SEEEEEEE?TTSS??TTEEEEEEE??????EE??? 4AQQ|A PF01687.12_Flavokinase_seed 139 259 !Q:4,5|12,26|31,35|38,38|40,45|55,89|93,151|155,155|163,173|175,175|177,178|186,201|203,205|207,215|218,218|230,234|236,236|254,254 Q:0,3|6,11|27,30|36,37|39,39|46,54|90,92|152,154|156,162|174,174|176,176|179,185|202,202|206,206|216,217|219,229|235,235|237,253|255,258 HHSS??EEEEEE??????-????????EEEE?---?SS?B????--SEEEEEEEE?----------------------------------GGG?----------------------------------------------------------EEE-EEEEEEE???-???---?S?E--EEEEEET----------------T?-?S---?----?TT?EEEEEEEEEEE?????S-STTHHHHHHHHHHHHHH-HHHH 1Q9S|A PF01693.11_Cauli_VI_seed 212 70 !Q:2,3|7,7|12,23|27,27|31,33|40,45|49,49|52,56|60,60|62,62 Q:0,1|4,6|8,11|24,26|28,30|34,39|46,48|50,51|57,59|61,61|63,69 EE--EEE?SSSS--?---------EEE-EEH---HHHHHH------SSS?SS??--?EEE-S?HHHHHHH 3BSU|A PF01694.17_Rhomboid_seed 65 239 !Q:5,5|9,13|20,21|24,24|47,52|68,70|79,79|81,106|125,125|129,162|164,167|180,183|187,216|235,235|237,238 Q:0,4|6,8|14,19|22,23|25,46|53,67|71,78|80,80|107,124|126,128|163,163|168,179|184,186|217,234|236,236 GGGTT?TTH-----HHHGGG??SS-HHHHHHHHHHHHHHHHHHHHHH-----?HHHHHHHHHHHHHHH---HHHHHHHH?S?----------------------???SHHHHHHHHHHHHHHHHH?GGG----------------------------------S????TTHHHHHHHHHH----HHS????????--------------------??THHHHHHHHHHHHHHHHT?S?? 3ZMI|A PF01695.12_IstB_IS21_seed 17 184 !Q:0,1|3,13|17,18|22,25|28,29|39,39|41,42|48,49|56,56|68,68|75,75|77,80|100,102|111,112|122,122|124,126|144,145|152,153|155,161|163,180 Q:2,2|14,16|19,21|26,27|30,38|40,40|43,47|50,55|57,67|69,74|76,76|81,99|103,110|113,121|123,123|127,143|146,151|154,154|162,162|181,183 ??S-----------STT??TTT????SH--HHHHHHHHH-H--HHHTS??EEEEEE?TTSSHHHHHHH-HHHHHH-T????EEEEHHHHHHHHHHHHTTS???HHHHHHHT?-SSEEEETTT?S???HHHHHHHHHHHHHHHHT??EEEEEE??S???????S------------------HHH 3ECC|A PF01698.11_FLO_LFY_seed 38 589 !Q:0,431|433,436|439,442|445,445|447,447|474,477|480,481|489,489|494,494|497,498|515,515|528,528|532,533|555,555|570,572 Q:432,432|437,438|443,444|446,446|448,473|478,479|482,488|490,493|495,496|499,514|516,527|529,531|534,554|556,569|573,588 ------?----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?------------------?----------------------------------------------------------------------------------------------------------------------------------------???????B????TT????SS?B?HHHHHHHHHHHHHHHHHHHHHHHHTT????SS??HHHHHHH-HHTT?TT??HHHHHHTHHHHHHHHH?HHHHHHHHHHHH-HTT??HHHHHHHTHHHHHHHHHTTTT?HHHHHHHSTTGGGS???HHHHHHHHHHHHHHHH 2VY1|A PF01699.19_Na_Ca_ex_seed 111 234 !Q:15,15|19,19|21,38|41,47|75,89|91,98|126,126|128,165|173,173|189,211|213,213|215,215 Q:0,14|16,18|20,20|39,40|48,74|90,90|99,125|127,127|166,172|174,188|212,212|214,214|216,233 HHHHHHHHHHHHHHH-HHH-T------------------SS?----??HHHHHHTHHHHHHHHHHHHHHHHHHHT---------------T-------?THHHHHHHHHHHHHHHHTHHHHHHHHS?B?-----------------------------------??HHHHHHH-HHHHHHHHHHHHTTT-----------------------T?B?HHHHHHHHHHHHHHHHHH 3V5S|A PF01700.11_Orbi_VP3_seed 7 892 !Q:0,49|64,67|73,77|81,82|84,84|87,87|92,92|103,106|109,109|129,129|135,136|147,147|153,155|163,163|177,177|179,179|181,183|188,188|194,197|238,239|243,244|253,255|257,257|260,261|284,285|291,293|303,303|307,309|316,319|337,337|343,348|352,353|369,371|374,376|378,378|396,397|400,402|405,406|409,409|413,414|417,418|430,431|435,436|444,445|448,449|451,452|455,455|457,459|462,462|466,469|471,473|481,483|498,498|528,528|533,534|548,551|553,555|558,561|571,571|578,579|617,617|620,621|634,634|649,651|661,667|689,689|691,691|699,704|713,713|716,717|720,720|724,726|734,734|746,746|758,759|764,768|778,780|786,787|795,796|799,799|801,801|808,809|817,821|824,825|830,831|834,835|843,843|846,847|852,852|861,861|868,868|875,876|882,882|886,891 Q:50,63|68,72|78,80|83,83|85,86|88,91|93,102|107,108|110,128|130,134|137,146|148,152|156,162|164,176|178,178|180,180|184,187|189,193|198,237|240,242|245,252|256,256|258,259|262,283|286,290|294,302|304,306|310,315|320,336|338,342|349,351|354,368|372,373|377,377|379,395|398,399|403,404|407,408|410,412|415,416|419,429|432,434|437,443|446,447|450,450|453,454|456,456|460,461|463,465|470,470|474,480|484,497|499,527|529,532|535,547|552,552|556,557|562,570|572,577|580,616|618,619|622,633|635,648|652,660|668,688|690,690|692,698|705,712|714,715|718,719|721,723|727,733|735,745|747,757|760,763|769,777|781,785|788,794|797,798|800,800|802,807|810,816|822,823|826,829|832,833|836,842|844,845|848,851|853,860|862,867|869,874|877,881|883,885 ??????????????????????????????????????????????????SSSHHHHHHHGGGG????EEESS?????EEE??S?SS?EEEE?SHHHHHHSSS????TT?HHHHHHHHHHHHHHHHHHH?EEEES??EEEETTEEEE?GGGSS???TTSTTTS?HHHHHHHHHHHTT?B?B???SSSS?EEEEE????HHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHTTEEE??GGG??SGGGGEEE???S?SS??HHHHHHSTTTHHHHHHHHHHHH??EEEEE???HHHHHHHTS?SSS???GGGGGG????HHHHHHHHHHHHHHHTS?SSEEB??????GGG??HHHHHHHHHHHHHHS???SS???B?HHHHHHHHHHHHHHHTT??SS???EE??SS?STT??EE--TTTTEEGGGGS??TTT??SSSSSSS??EE??S??SS?S???EE?GGG????S???STTTSSS???SHHHHHHHHHHHHS?HHHHHHHHTTHHHHHHHHHHHHHHHHTTS?STTS??HHHHHHHHHHHHH????S???EE????TTHHHHHHT?EEEEEE??TTTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTT?SS??HHHHHHHHHHHS?HHHHHHHHHHHHHH???HHHHHHHHH???????HHHHHHHHHHHHTTSSTTTTB?S?EEEEEEE??????SSGGGGGS?TT??BS?BSS???GGGEEEE?HHHHHHHHHTT?HHHHHHHHHHT??EEEE?????EEEEEEESS???HHHHS??SEEEEEE??TT-T?EEEEEE??EEEEEEE?????TT??TGGG??SS??EEEEEEB?SS??SEEE?STTSGGGG?SEEEEE?TTSEEE??GGGGG?EEE?????? 2BTV|A PF01701.13_PSI_PsaJ_seed 31 40 !Q:0,0|3,5|36,38 Q:1,2|6,35|39,39 ?HH---HHHHTTBHHHHHHHHHHHHHHHHHHHHHHS???S 2WSE|J PF01702.13_TGT_seed 133 431 !Q:4,4|11,11|13,13|15,17|21,30|32,36|38,42|44,44|68,93|100,100|107,108|111,111|114,116|127,127|129,138|140,143|148,153|155,155|157,157|162,168|170,170|179,179|184,190|193,205|209,209|213,213|216,218|231,232|236,236|241,241|250,254|257,302|304,316|322,322|327,329|331,331|333,334|338,339|344,356|358,364|366,367|379,379|409,410|422,427|429,430 Q:0,3|5,10|12,12|14,14|18,20|31,31|37,37|43,43|45,67|94,99|101,106|109,110|112,113|117,126|128,128|139,139|144,147|154,154|156,156|158,161|169,169|171,178|180,183|191,192|206,208|210,212|214,215|219,230|233,235|237,240|242,249|255,256|303,303|317,321|323,326|330,330|332,332|335,337|340,343|357,357|365,365|368,378|380,408|411,421|428,428 HHHH-HHHHHH-T?S---EEE??????---?S-----S?---?H-HHHHHHHHHHHHHHHHHHHHHHT-------------------------?HHHHHH?EEEEEE??TT?HH---HHHHHHHHHH-H----------H?--?SEEE------E?S?SSSS------?H-HHHHHHHH-HHGG-------GS?------------TTS?EEE-TT??-SHHHHHHHHHTT??EEE?SHHH-HHHHHTEE?---?TT?--------------------------------------------?E-------------ETTSG-GGTT??-S?S--SSS??SHHH-------------H-------H??HHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHTT-?HHHHHHHHHHH------H?? 3TLL|A PF01704.13_UDPGP_seed 8 477 !Q:16,16|19,20|22,23|29,31|37,41|50,57|70,72|79,80|87,100|105,105|122,122|124,127|133,134|148,149|151,151|155,155|157,157|162,165|168,168|174,175|178,178|182,183|186,187|189,190|195,197|219,220|226,226|230,230|233,236|246,249|251,252|261,262|269,269|282,282|287,287|296,296|300,306|314,316|331,336|338,339|342,362|365,366|368,369|380,380|384,384|387,387|389,389|392,393|395,396|399,399|414,414|421,421|424,425|428,430|435,435|448,448|451,453|455,455|470,470|473,473 Q:0,15|17,18|21,21|24,28|32,36|42,49|58,69|73,78|81,86|101,104|106,121|123,123|128,132|135,147|150,150|152,154|156,156|158,161|166,167|169,173|176,177|179,181|184,185|188,188|191,194|198,218|221,225|227,229|231,232|237,245|250,250|253,260|263,268|270,281|283,286|288,295|297,299|307,313|317,330|337,337|340,341|363,364|367,367|370,379|381,383|385,386|388,388|390,391|394,394|397,398|400,413|415,420|422,423|426,427|431,434|436,447|449,450|454,454|456,469|471,472|474,476 HHHHHHHHHHHHHHHH-HS??S??GGGEE???TTTEE-----EHHHHHSS?-----??STTGGGEEEEEE???BSGGGT??SBSTTS??------------BTTB?HHHHHHHHHHHHHHHH-T-???EEEEE??TTTHHHHHHHHGG--G?SSS?E-EEEE????EE?EETTT??BS?SSS--SS-?T--TSEE???GGGHHHHHHHHTHHHHHHHTT??EEEEE?TTB-SS????HHHHHHHHH----S??SEEEEEEE??GGGSSS?EEEEETTEEEEE?GGGS?TTSHHHHT?TTT-----??EEEEEEE---EEEHHHHHHHHHTT??????B??EE??????-----------????EE??B??GGGGGGGSSS?EEE-EE?G-GG??B??SH-HHHHHHTSTTEEEE-TTEEEE?TT??SS-??EEEE?GGGSSHHHHHHH?SS??-B?TTEEEEEEESSEEE?TT?EEE 1Z90|A PF01706.11_FliG_C_seed 154 125 !Q:5,5|8,8|21,21|26,26|30,30|42,43|47,49|58,58|61,68|78,78|92,97|121,124 Q:0,4|6,7|9,20|22,25|27,29|31,41|44,46|50,57|59,60|69,77|79,91|98,120 HHHHH-HH?HHHHHHHHHHHS?GGGG-GGS?HHHHHHHHTTS?-HHH---HHHHHTTS?HH--------HHHHHHTTS?HHHHHHHHHHHHH????-?HHHHHHHHHHHHHHHHHHHHTTS???? 3HJL|A PF01707.11_Peptidase_C9_seed 8 209 !Q:0,40|45,45|48,48|63,66|74,74|81,84|100,100|104,104|110,110|113,113|117,119|122,122|125,125|129,130|132,132|134,134|138,139|150,150|156,157|159,159|161,161|164,164|168,169|173,174|178,179|181,181|189,191|194,195|197,201 Q:41,44|46,47|49,62|67,73|75,80|85,99|101,103|105,109|111,112|114,116|120,121|123,124|126,128|131,131|133,133|135,137|140,149|151,155|158,158|160,160|162,163|165,167|170,172|175,177|180,180|182,188|192,193|196,196|202,208 ----------------------------------???????TTTT?SS?HHHHHHHHHHHHTT????HHHHHHH?HHHHTT????HHHHHHHHHHHHHSS?GGG?TTBSS?EE?EEE???SS?SS?EEE??S?S?EEB??HHHHHHHTTT?THHHH??T-T?EE?TTT??EES??TTS??S?TTBEESS???SS??B?????THHHHTT 3TRK|A PF01709.15_Transcrip_reg_seed 257 347 !Q:0,0|15,15|33,43|59,60|70,88|94,98|106,106|117,117|133,133|135,135|138,139|157,170|173,173|179,182|184,185|190,193|195,195|197,197|201,216|219,230|232,235|237,250|252,255|257,258|277,277|279,282|284,289|291,291|300,300|303,310|312,312|314,320|344,347 Q:1,14|16,32|44,58|61,69|89,93|99,105|107,116|118,132|134,134|136,137|140,156|171,172|174,178|183,183|186,189|194,194|196,196|198,200|217,218|231,231|236,236|251,251|256,256|259,276|278,278|283,283|290,290|292,299|301,302|311,311|313,313|321,343 ?SGGGTSSSTTTTTS?HHHHHHHHHHHHHHHHH?-?-?-?????STTTHHHHHHHHHTT??HHHHHHHHS??-??---?--?--?????EEEEE-----EEEETTT-EEEEEEEEES?HHHHHHHHHHHHHTT-T?EE??TTSSGGGEEEEEEEEES--------------SS?HHHHH----H--HHHH----H-T?SEE----------------EE---------?--T----T--------------S?---E--EEEEEGGGHHHHHHHHHH-T----T?---??S-EEEEEEEE-SS????---?T-T-------TSHHHHHHHHHHHHSSSEEEEEE???- 1KON|A PF01712.14_dNK_seed 14 179 !Q:26,26|33,33|50,50|52,52|74,77|79,80|88,89|101,102|106,114|117,118|121,126|135,136|144,148|150,150|156,157|166,166|170,174 Q:0,25|27,32|34,49|51,51|53,73|78,78|81,87|90,100|103,105|115,116|119,120|127,134|137,143|149,149|151,155|158,165|167,169|175,178 HHHHHHHHHHHHHHHHTTSGGGTSSS?EEEEES?HHHHHHTHHHHHHHTT?S?HHHHHHHHHHHHHHHHHSHHH----H??SEEEEEE??HHHHHHHHHHH??GGG---------GS??HH------HHHHHHHH--HHHHHTS?????S?GGGGG??EEEEETTS?TTT---??HHHH 1ZMX|A PF01713.16_Smr_seed 123 134 !Q:2,2|5,6|9,10|28,47|52,52|55,56|59,80|83,83|85,90|100,103|106,106|115,118|123,123|133,133 Q:0,1|3,4|7,8|11,27|48,51|53,54|57,58|81,82|84,84|91,99|104,105|107,114|119,122|124,132 EE?TT??HH--HHHHHHHHHHHHHHHTT?-------------------SEEE-EE??ST----------------------TS-H------HHHHHHHHH----HH?TTEEEEEE?--?TTTT-GGGEEEEEE? 3QD7|X PF01715.12_IPPT_seed 12 284 !Q:6,7|12,14|22,22|28,28|30,30|34,36|49,52|60,60|68,68|78,88|115,115|123,123|126,126|143,143|151,166|177,177|211,219|240,243|246,247|273,273|276,277 Q:0,5|8,11|15,21|23,27|29,29|31,33|37,48|53,59|61,67|69,77|89,114|116,122|124,125|127,142|144,150|167,176|178,210|220,239|244,245|248,272|274,275|278,283 TTTBTT??TTTT???HHHHHHS?EETSS?B?TTS???HHHHHHHHHHHH----HHHHHTT?EEEEEES?HHHHHHHHS????????--?HHHHHHHHHHHHHHHHHHHHHHHHHH?HHHHHHS?TT?HHHHHHHHHHHHHHSS?HHHHHTS-----------?????SSEEEEEEEE?SSHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHS------???TTSTTTTSTTHHHHHHHHHT----SS?-HHHHHHHHHHHHHHHHHHHHHHHHS?SS-?EEEETT 3CRM|A PF01716.13_MSP_seed 8 247 !Q:0,5|18,22|25,28|31,32|36,37|53,56|59,63|67,67|70,70|72,72|74,76|84,85|87,87|91,91|101,101|109,109|113,113|121,121|128,129|131,132|136,136|139,140|149,149|152,152|155,157|162,162|170,172|179,179|183,183|190,193|206,207|223,225|231,233|247,247 Q:6,17|23,24|29,30|33,35|38,52|57,58|64,66|68,69|71,71|73,73|77,83|86,86|88,90|92,100|102,108|110,112|114,120|122,127|130,130|133,135|137,138|141,148|150,151|153,154|158,161|163,169|173,178|180,182|184,189|194,205|208,222|226,230|234,246 ??????GGGTTTTTGGGS?????SS????EE??SSS??EEEEEEEEEEEEEEE????SS?????EEE?EE?S?S???EEEEEEE??B?TTS?BEEEEEEEE?EEEEEEE?SSS?EEEEEEE?EEEEEE??S??SEE?SS??EEEEEEEE?SS?TT???TTSB?SSSSBSS--?TTSTTS?STT-THHHHS????EEEEEEEEEEEE??TTTTEEEEEEEEEEE???TTTTS???EEEEEEEEEEEEE- 3PRR|O PF01717.13_Meth_synt_2_seed 14 352 !Q:1,1|4,6|9,12|14,32|52,53|57,58|60,60|63,63|65,65|78,78|80,81|84,85|95,97|100,100|102,106|108,108|121,121|124,126|133,133|144,147|151,151|169,169|176,177|183,183|185,187|193,194|198,199|221,221|230,230|232,232|234,235|240,242|249,250|255,256|261,261|273,275|279,280|284,284|289,289|291,292|308,316|318,318|323,323|326,326|329,329|334,334 Q:0,0|2,3|7,8|13,13|33,51|54,56|59,59|61,62|64,64|66,77|79,79|82,83|86,94|98,99|101,101|107,107|109,120|122,123|127,132|134,143|148,150|152,168|170,175|178,182|184,184|188,192|195,197|200,220|222,229|231,231|233,233|236,239|243,248|251,254|257,260|262,272|276,278|281,283|285,288|290,290|293,307|317,317|319,322|324,325|327,328|330,333|335,351 S?BB?-?SB????S????????????????-??HHHHHHHHHHHHHHHHHSS??SBB??B?TT?S?TTHHHHTTSTTE-E??SS??EEEETTEEE???EE?S?????S?SSTHHHHHHTTS?SS?--BEEEEE?HHHHHHTSEE?---TTS?HHHHHHHHHHHHHHHHH-HHHHTT??EEEEE?T---TSSTT??SSG--GGHHHHHHHHHHHHHHHHTTS?SSSEEEEE?S?S??TTTH---HHHHTT??SEEE??BSSS?TTGGGGGTTTT???SEE??BSS?TTSS-S??THHHHHHHHHHHHHS---------S?STTB?BB?SS?SSSS?HHHHHHHHHHHHHHHHH 3PPH|A PF01719.12_Rep_2_seed 24 257 !Q:0,3|6,18|26,26|28,29|33,38|46,47|51,51|53,53|57,57|59,59|61,63|65,66|68,78|81,82|84,86|112,112|114,118|121,121|123,123|127,128|130,130|141,141|150,154|158,158|164,170|175,178|181,181|186,187|201,205|223,225|249,249|254,256 Q:4,5|19,25|27,27|30,32|39,45|48,50|52,52|54,56|58,58|60,60|64,64|67,67|79,80|83,83|87,111|113,113|119,120|122,122|124,126|129,129|131,140|142,149|155,157|159,163|171,174|179,180|182,185|188,200|206,222|226,248|250,253 ????EE-------------EEEEEEE?G--GGS-----?TTHHHHH--HHT?S?EEE?S?B???B??S-----------SS??B???BEEEEEEEEEEEEHHHHHHHHHHHH?T-----TS?S?EEE?-S?HHHHHHHTTT?SHHHHHTT?????TTS?EEETT?-----?GGGG????HH-HHHH--HHHHHHHHHHHTT??---SHHHHHHHHHHHHHHHT?-?HHHHHHHHTTTHHHHHHHHHHHH-HHHT??? 3DKY|A PF01721.13_Bacteriocin_II_seed 19 36 !Q:0,3|6,9|13,15 Q:4,5|10,12|16,35 ????SS????TTS???SSHHHHHHHHHHHHHHSSST 3LEU|A PF01722.13_BolA_seed 238 113 !Q:1,1|7,9|11,14|19,23|26,47|49,54|61,61|65,65|68,69|84,84|87,88|91,94|96,99|102,102|104,104|107,108 Q:0,0|2,6|10,10|15,18|24,25|48,48|55,60|62,64|66,67|70,83|85,86|89,90|95,95|100,101|103,103|105,106|109,112 H-HHHHT-??S-?-?EEEE?????SS??-------------------?S---???EEEEEE?GGG-SS??SSHHHHHHHHHTHH-HH--HT----T????EE-E-EE?-HHHH 2DHM|A PF01724.11_DUF29_seed 89 169 !Q:0,0|4,4|23,23|27,27|30,31|48,48|71,71|73,76|96,99|101,101|107,108|115,118|125,125|134,145|148,149|152,152|155,157|166,167 Q:1,3|5,22|24,26|28,29|32,47|49,70|72,72|77,95|100,100|102,106|109,114|119,124|126,133|146,147|150,151|153,154|158,165|168,168 ?TTT?HHHHHHHHHHHHHHHHHH?SSS?TT??HHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHSTT?T----THHHHHHHHHHHHHHHHHH?--?G-GGGGG??HHHHHH----HHHHHH-HHHHHHTT???--------?TT??SS?SS--?HHHHHSTT??H 3FCN|A PF01725.11_Ham1p_like_seed 110 368 !Q:4,6|22,25|29,30|34,40|45,59|78,89|92,110|126,129|138,153|155,166|169,177|181,182|187,190|195,196|201,204|208,216|232,232|235,246|249,264|271,272|276,276|279,284|286,286|291,302|309,309|311,313|316,319|327,330|336,343|355,359|364,366 Q:0,3|7,21|26,28|31,33|41,44|60,77|90,91|111,125|130,137|154,154|167,168|178,180|183,186|191,194|197,200|205,207|217,231|233,234|247,248|265,270|273,275|277,278|285,285|287,290|303,308|310,310|314,315|320,326|331,335|344,354|360,363|367,367 EEES???HHHHHHHHHHHGGGT----EEE--EET-------TTTT----??--?????-?SSHHHHHHHHHHHHHHHH------------SS?------------------EEEEEEEEEEGGGTT---?BGGGSTTT----------------T-----------?TT?-------?HHH--HHHH----HHHH--TTTS?---GGG--------?EEEEEEEEEEESSTT?SS-----------?EE----------------EEEEEE--EEE?SS??--??S-SSTT------------GGGEEE-G---GG----TEEGGGS---?HHHHH--------HHSHHHHHHHH-----HHHH---H 2I5D|A PF01726.11_LexA_DNA_bind_seed 9 65 !Q:0,4|24,26|36,36|38,38|58,58|61,61|64,64 Q:5,23|27,35|37,37|39,57|59,60|62,63 ?????HHHHHHHHHHHHHHHHHSS???HHHHHHHHT?S?HHHHHHHHHHHHHTTSEEE?SS?TT? 3JSP|A PF01728.14_FtsJ_seed 239 652 !Q:0,0|2,4|18,85|88,90|92,92|98,98|101,101|112,165|177,206|213,222|225,225|227,241|245,248|253,253|260,260|262,263|265,359|366,395|397,403|408,408|414,417|426,426|432,459|462,480|485,502|510,530|535,535|537,537|546,552|557,609|614,615|617,626|629,629|631,631|634,635|638,641|643,645 Q:1,1|5,17|86,87|91,91|93,97|99,100|102,111|166,176|207,212|223,224|226,226|242,244|249,252|254,259|261,261|264,264|360,365|396,396|404,407|409,413|418,425|427,431|460,461|481,484|503,509|531,534|536,536|538,545|553,556|610,613|616,616|627,628|630,630|632,633|636,637|642,642|646,651 ?S?--HHHHHHHHHHHHH-----------?-------??----------------------------------------------?TT--?E-EEEES?TT?HHHHHHHHHH-----------------------------------------------------?TTSEEEEEESS??--------------------???-----TTEEEE----------ES?T---------------TSH----HHHH-HHHHHH-T--T---------------------------------------------------------------------------------------------??EEEEEE??-----------------------?????S-----?-HHHH-HHHHH----HHHHHHHH-HHHHH----------------------------EE-------------------EEEE------------------EEEEEES---------------------STTH-H-HHHHHHHH-------HEEE-----------------------------------------------------EEEE??T----------TS?T-TS-?EE----E---EEEEEE 1R6A|A PF01729.14_QRPTase_C_seed 18 214 !Q:16,17|22,23|25,27|30,31|44,44|46,56|65,65|75,77|90,91|95,97|102,102|114,122|125,129|134,172|179,191|193,193|198,198|205,209 Q:0,15|18,21|24,24|28,29|32,43|45,45|57,64|66,74|78,89|92,94|98,101|103,113|123,124|130,133|173,178|192,192|194,197|199,204|210,213 HHHHHHHHHHHHHHTT??SEEE??S???TT-?HHHHHHHHHHHT?B-------????STTSSEEE?HHHHHHHTS---HHHHHHHHHHHH-?SSS?--EEEE?SSHHHHHHHHH---------HT----?SEEE????---------??--??????????-??????-????EEEEES?????????????S?SEEE?GGGTSS?????EEEE 3C2O|A PF01730.11_UreF_seed 171 240 !Q:2,2|4,5|35,35|40,48|50,50|52,57|71,72|94,94|96,98|100,110|121,126|129,179|193,194|220,221|235,238 Q:0,1|3,3|6,34|36,39|49,49|51,51|58,70|73,93|95,95|99,99|111,120|127,128|180,192|195,219|222,234|239,239 SS?S--HHHHHHHHHHHHTTHHHHTHHHHHHHHHH-HHHT---------T?H------HHHHHHHHHHHHT??SHHHHHHHHHHHHHHHHHHHH?T---T?-??-------HHHHHHHHHH?-----SS?-------------------------------------------------?HHHHHHHHHHHHT??HHHHHHHHHHHHHHHHHHHHHHHTT??HHHHHHHHHHTHH----H 2WGL|A PF01731.15_Arylesterase_seed 6 86 !Q:16,16|18,19|32,34|41,41|44,45|61,61|65,65|83,83 Q:0,15|17,17|20,31|35,40|42,43|46,60|62,64|66,82|84,85 EEEEEEETTEEEEEES?S??SHHHHHHHHHTT???EEEEEE?TT??EEEEEEESSEEEEEE?TTS?EEEEEEGGGTEEEEEEE?TT 4HHO|A PF01734.17_Patatin_seed 116 569 !Q:3,5|9,9|11,14|24,27|29,60|65,65|69,70|75,75|83,133|140,144|155,156|162,162|164,164|169,169|171,171|182,201|215,215|217,219|224,230|252,254|266,266|277,299|304,304|306,307|309,309|312,313|315,364|367,367|380,380|388,388|410,410|412,417|424,453|457,459|463,466|471,507|510,510|512,519|521,529|532,541|543,543|546,551|554,554|556,565 Q:0,2|6,8|10,10|15,23|28,28|61,64|66,68|71,74|76,82|134,139|145,154|157,161|163,163|165,168|170,170|172,181|202,214|216,216|220,223|231,251|255,265|267,276|300,303|305,305|308,308|310,311|314,314|365,366|368,379|381,387|389,409|411,411|418,423|454,456|460,462|467,470|508,509|511,511|520,520|530,531|542,542|544,545|552,553|555,555|566,568 EEE???SSG-G----GTHHHHHHH----H--------------------------------HHTT?GGG??EEEE?THHHHHH---------------------------------------------------HHHHTT---??HHHHHHHHTT??TTTTS?S?SSSS?B?SHHHHHHHHH--------------------HHHHHHHHHHTTS?S???STHH-------HHHHHHHHHHHHHHHHHHHTT???SSHHHHHHHHH?HHHHHHHHHH-----------------------HHTS?S??B?TT??B?-----------------------------------------------??SS?BHHHHHHHHHHS?GGGGGGS?EEEEEEEETTTTEEEEEETTT?T------TSBHHH------------------------------HHH---HHT--??TTTB-----------------------------------??EE?T--------T??-------EE----------E?TT------SS-S?----???-?TTS 4AKF|A PF01735.13_PLA2_B_seed 15 533 !Q:5,7|24,35|39,39|49,49|60,64|67,67|74,74|89,90|92,93|97,98|100,100|107,109|121,124|140,143|148,148|155,156|163,163|165,165|174,179|182,184|188,188|195,195|198,198|201,202|211,211|227,231|252,264|272,273|280,311|331,331|335,335|338,338|342,342|347,396|398,398|405,405|410,410|413,413|418,419|421,421|424,426|433,436|442,442|444,444|459,465|473,473|475,475|481,483|486,486|489,492|499,501|514,515|524,526|530,530 Q:0,4|8,23|36,38|40,48|50,59|65,66|68,73|75,88|91,91|94,96|99,99|101,106|110,120|125,139|144,147|149,154|157,162|164,164|166,173|180,181|185,187|189,194|196,197|199,200|203,210|212,226|232,251|265,271|274,279|312,330|332,334|336,337|339,341|343,346|397,397|399,404|406,409|411,412|414,417|420,420|422,423|427,432|437,441|443,443|445,458|466,472|474,474|476,480|484,485|487,488|493,498|502,513|516,523|527,529|531,532 EEEEE???HHHHHHHHHHHHHHHH------------HTS?GGGEEEEEE?HHHHHHHHHH-----HH?TTTTTS?HHHHHHHHHHHHHS?-G--GGG??H-HHHHHH---HHHHHHHHHTT????HHHHHHHHHHHHHHG----GGTT?BSGGGG--GGTTTS?S?EEEEEEEE??----SS???GGG-SEEEEE?SS?EE--ETTTTEEE?GGGTTSEEETTEEEE?????BHHHHHHHHTTHHHHTHHHH???-?????????HHHHHHH??HHHHTT-???????-?????????????????-?????TTHHHHHHHHHHHHHHTSS?TTS?SS?EEE?TTTT???????????????????-??????????????????????---????-S?SEEEEE?GGGT?SS?HHHH??G-GG???EEEEEE????SSTTS?S?HHHHHHHHHHHHTT???????TTHHHHH?S?SEEEE???SS?SS????EEEEEE???SGGGTEEETTEE??SHHHHHHH???SSS?TT 1CJY|A PF01737.12_Ycf9_seed 35 59 !Q:26,26|28,28|58,58 Q:0,25|27,27|29,57 HHHHHHHHHHHHHHHHHHHHHHHHHS?S?SSSHHHHHHHHHHHHHHHHHHHHHHHHHH? 3PRR|Z PF01738.13_DLH_seed 17 280 !Q:1,1|6,7|11,14|23,24|29,32|47,48|54,54|63,82|84,85|97,97|103,104|113,119|131,131|142,142|144,144|158,160|169,169|171,180|191,192|194,194|203,203|207,207|211,213|222,222|225,225|236,237|242,242|247,257|259,260|279,279 Q:0,0|2,5|8,10|15,22|25,28|33,46|49,53|55,62|83,83|86,96|98,102|105,112|120,130|132,141|143,143|145,157|161,168|170,170|181,190|193,193|195,202|204,206|208,210|214,221|223,224|226,235|238,241|243,246|258,258|261,278 E?EEEE??SSS----SEEEEEEE??TTBS?---HHHHHHHHHHHHTT-?EEEEE?GGGGTSTT-------------------?B??TTSHHHHHHHH-HHHHT??HHHHHHHH-------HHHHHHHHTST-TEEEEEEEEE-E?HHHHHHHHHHHHT--?SSEEEEES?S-------?--GGGGGGGGGG??S?EEEEEETT?TTS?HHH---HHHHHHHH-TT?TTEEEEEETT??TTTT?TTST-----------T??HHHHHHHHHHHHHHHGGG? 1ZI9|A PF01739.13_CheR_seed 22 213 !Q:0,3|20,26|29,32|34,35|42,43|59,61|64,64|66,66|69,70|80,80|98,98|102,102|113,114|118,118|121,121|125,125|137,138|141,141|143,144|146,151|158,158|165,165|189,189|192,194|196,196|199,199 Q:4,19|27,28|33,33|36,41|44,58|62,63|65,65|67,68|71,79|81,97|99,101|103,112|115,117|119,120|122,124|126,136|139,140|142,142|145,145|152,157|159,164|166,188|190,191|195,195|197,198|200,212 ????TTTTTTHHHHHHHHHH-------HS?---S?-EEEEES??TTTHHHHHHHHHHHH---HH?S?TT--SEEEEEEES?HHHHHHHHHTEEEGGGG-TTS?HHHHHHHEEE??TTS?SE-EEE?HHHHTTEEEEE??TT?S--S??????EEEEEE?SSGGGS?HHHHHHHHHHHGGGEEEEEEEEE?TT???T-TT?TTEEEEETTEEEE 3UJA|A PF01740.16_STAS_seed 68 215 !Q:10,13|22,22|43,126|136,137|141,141|157,157|161,162|168,169|176,184|192,192|196,205 Q:0,9|14,21|23,42|127,135|138,140|142,156|158,160|163,167|170,175|185,191|193,195|206,214 EEEEEEETTE----EEEEEEEE-ESHHHHHHHHHHHHHHHHSS?---------------------------------------------------------------------------------??EEEEEEEEE--EEE?HHHHHHHHHHHHHHH-HTT??EEEES??HHHHHH---------HHHHTGG-GTS----------EEESSHHHH 3NY7|A PF01741.13_MscL_seed 8 153 !Q:0,0|11,11|45,45|47,51|55,58|60,62|65,76|78,78|82,82|112,115|120,126|128,130|133,136 Q:1,10|12,44|46,46|52,54|59,59|63,64|77,77|79,81|83,111|116,119|127,127|131,132|137,152 ?HHHHHHHHHS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-H?-???EEE????T---TT?----------?S?EEE?HHHHHHHHHHHHHHHHHHHHHTHHHHHHH----HHTT???---?H---HH----HHHHHHHHHHHHHHHT 2OAR|A PF01742.12_Peptidase_M27_seed 13 455 !Q:0,7|11,13|22,22|29,31|45,45|47,49|52,53|56,57|61,62|65,66|68,68|71,75|80,80|115,118|120,149|153,153|158,160|184,184|190,192|197,198|203,205|214,214|221,223|228,229|234,234|237,237|240,240|242,243|246,246|248,252|255,256|275,279|281,284|287,287|290,291|294,300|308,308|316,316|341,342|346,346|349,352|369,369|373,373|377,377|393,393|403,406|408,408|410,416|419,421|424,424|428,428|435,436|441,441 Q:8,10|14,21|23,28|32,44|46,46|50,51|54,55|58,60|63,64|67,67|69,70|76,79|81,114|119,119|150,152|154,157|161,183|185,189|193,196|199,202|206,213|215,220|224,227|230,233|235,236|238,239|241,241|244,245|247,247|253,254|257,274|280,280|285,286|288,289|292,293|301,307|309,315|317,340|343,345|347,348|353,368|370,372|374,376|378,392|394,402|407,407|409,409|417,418|422,423|425,427|429,434|437,440|442,454 ????-???TTS???SSSEEEEE?GGGTTT???EEEEEEETTEEEE?S???TT??GG--GGS??TT??S?TT-????TTTT?SHHHHHHHHHHHHHHHHHHHTSHHHHHHHHHHHH????S??----------------------------TTS?TTEE???STTTEEEEEEEETTTEEEEEEEE?SEEEE???SSTT??EEEE??-EEETTEEE?GGGTTS???EEEE??SSEE?EE?SS?S??TT?S?????EE??HHHHHHHHHHHHHHHHTT??-??S????SS?SS??SS????-??HHHHHHH?GGGGGGS?HHHHHHHHHHHHHHHHHHHHHHTT??EES?TT--??HHHHHHHHHHHHTEEE?TTS?EEE?HHHHHHHHHHHHTSS?HHHHHHHHT????S?S???????EE???SS?TTT?BTTTBT??GGGT?SGGGGGGBTTTSG 2IMB|A PF01743.15_PolyA_pol_seed 21 173 !Q:3,3|14,19|21,30|35,43|45,45|54,54|58,59|61,67|71,71|76,76|79,81|83,86|92,123|132,132|137,139|141,145|149,154|156,157|161,161|171,172 Q:0,2|4,13|20,20|31,34|44,44|46,53|55,57|60,60|68,70|72,75|77,78|82,82|87,91|124,131|133,136|140,140|146,148|155,155|158,160|162,170 EEE?TTTHHHHHHS???---S-------???EEES---------S?TTHHHHHS-SSS??B-----??SSS?EEEE?SS--?E----EEEEE?????-??????????????????????????HHHHHTTS?BGGG???B?----TTT??----B??SST-HHHHHHTTB?? 3AQK|A PF01745.11_IPT_seed 7 240 !Q:0,0|7,7|12,12|25,26|31,32|37,37|46,48|55,55|59,59|61,65|69,69|71,72|90,90|99,100|110,110|117,117|124,128|145,147|151,152|188,189|196,197|199,200|226,239 Q:1,6|8,11|13,24|27,30|33,36|38,45|49,54|56,58|60,60|66,68|70,70|73,89|91,98|101,109|111,116|118,123|129,144|148,150|153,187|190,195|198,198|201,225 ?EEEEEE?STTS?HHHHHHHHHHHH??EEEE??SGGG?GGGHHHHT???SGGGTT?EEE?S?-???GGG?S??HHHHHHHHHHHHHTTTT-SSEEEEEE??HHHHHHHHH?TTTSSS?EEEEEE?????HHHHHHHHHHHHHHHH???SSS??HHHHHHHTTSSTTHHHHHTTSTTHHHHHHHHHHTT??GGGGGG??H--HHHHHHHHHHHHHHHHHHHHHHHHS????----?????? 3EPJ|A PF01746.16_tRNA_m1G_MT_seed 23 226 !Q:9,9|15,15|20,21|25,27|30,31|34,35|38,38|41,41|57,57|59,62|64,64|76,77|85,87|90,90|92,95|101,103|106,108|116,116|118,121|130,131|133,133|153,172|174,184|186,186|189,190|196,197|203,204|224,224 Q:0,8|10,14|16,19|22,24|28,29|32,33|36,37|39,40|42,56|58,58|63,63|65,75|78,84|88,89|91,91|96,100|104,105|109,115|117,117|122,129|132,132|134,152|173,173|185,185|187,188|191,195|198,202|205,223|225,225 HHHHHHTTS?EEEEE?GGGG??STT???EE??TT??SS?EE?HHHHHHHHHHHHHHH?T----T?EEEEEEEEEEE??HHHHHHH---HT?S----EEEEE???TT???HHHHHHH?S----EEEESSSS??S?SHHHHHHHHHHHHTTSTTT?????-???????----???S??????----?S?SE--ETTEE??HHHHS??HHHHHHHHHHHHHHHHHHH?H 4IG6|A PF01747.12_ATP-sulfurylase_seed 113 307 !Q:0,0|5,10|19,19|22,22|25,25|27,29|34,36|39,41|44,44|56,56|58,58|61,68|73,75|77,77|80,81|85,86|101,101|104,120|127,127|130,131|133,138|155,155|161,161|166,168|170,170|172,175|178,178|180,181|184,184|195,207|213,214|216,216|221,224|227,227|236,236|238,277|286,289|294,294|305,305 Q:1,4|11,18|20,21|23,24|26,26|30,33|37,38|42,43|45,55|57,57|59,60|69,72|76,76|78,79|82,84|87,100|102,103|121,126|128,129|132,132|139,154|156,160|162,165|169,169|171,171|176,177|179,179|182,183|185,194|208,212|215,215|217,220|225,226|228,235|237,237|278,285|290,293|295,304|306,306 ?GGGB??----HHHHHHHH-HH-HT?S--?EEEE??-SS???HH-HHHHHHHHHHH-H-TS--------EEEE??-B?SB??TTS??HHHHHHHHHHHHHH-HS----------------?TTTEEE?BB??B?--???THHHHHHHHHHHHHTT?SEEEE?TTTT???B?T----TS?B--SS?TTHHHHHHHH-------------HHHHH--T?EEEE????EE-ETTTTEEE?S----------???-?????????????-----------??THHHHTTT????TTTS?HHHHHHHHHH-S 1G8G|A PF01749.15_IBB_seed 18 104 !Q:0,5|9,26|31,34|36,40|42,43|45,80|90,90|97,97 Q:6,8|27,30|35,35|41,41|44,44|81,89|91,96|98,103 ??????GGG??????????????????TTSS????S?????S??S?-??????????????????????????????????HHHHHHHHS?SSHHHH-HHHHHH 1WA5|B PF01750.13_HycI_seed 27 145 !Q:12,13|15,20|30,31|41,45|54,55|58,58|60,60|63,63|75,75|78,79|81,81|83,83|101,103|112,113|115,117|119,122|126,127|145,145 Q:0,11|14,14|21,29|32,40|46,53|56,57|59,59|61,62|64,74|76,77|80,80|82,82|84,100|104,111|114,114|118,118|123,125|128,144 HHHHHHHHHHEE??T------TEEEEEEET??GGGHHHHSS----?SEEEEEEE??SS?S?TT?EEEEETTHHHH-HH??S-S?HHHHHHHHHHHHHHHTT???SEEEEEEE??S???S----BSS??HHHHTTHHHHHHHHHHH- 2KML|A PF01751.17_Toprim_seed 136 234 !Q:6,6|19,20|28,39|52,52|58,59|61,62|66,66|83,83|88,88|93,99|102,103|106,106|108,109|112,112|116,117|119,119|135,178|181,181|187,189|193,197|208,208|215,215|217,217|219,225|228,230 Q:0,5|7,18|21,27|40,51|53,57|60,60|63,65|67,82|84,87|89,92|100,101|104,105|107,107|110,111|113,115|118,118|120,134|179,180|182,186|190,192|198,207|209,214|216,216|218,218|226,227|231,233 EEEEES?HHHHHHHHHHHT??EEEEETT------------EEEEEEEETTEE-EEEEE??S??EEE?SSSTBTTBEEETTEEE?EEEE?EEET-------TT??EE?S??SS?TTT??S?EEEHHHHHHHHHHHH--------------------------------------------HH?SEEEE???SSH-----HHHHHHHHHH-HHHTTT?S?E-------EE???SSS 1CY1|A PF01752.12_Peptidase_M9_seed 7 318 !Q:0,96|98,98|113,113|117,117|125,125|142,143|145,145|150,150|170,170|174,175|182,182|188,188|196,198|202,202|205,205|221,223|227,227|230,230|233,233|235,235|258,258|262,262|264,265|276,277|282,283|290,292|295,296|313,313 Q:97,97|99,112|114,116|118,124|126,141|144,144|146,149|151,169|171,173|176,181|183,187|189,195|199,201|203,204|206,220|224,226|228,229|231,232|234,234|236,257|259,261|263,263|266,275|278,281|284,289|293,294|297,312|314,317 ----------?-----------------------------?-------------------------------------------?????????????S?EEEEETTTTEEEEE?TTS?HHHHHHH-HHHHHHHHHHHHHHHS??S?SSSS?GGGSEEEEEESSHHHHHHH-TTT??GGGGGT?EEEGG-GTEEEEE???GGG?SS?HHHHHHHHHHHHHHH---HHT?SS?TT?S-GGGGGGTTHHHHHHHHHHHTTB?SSS?B??BHHHHHTTTT??GGGS??HHHHTT???SS??HHHHHHHHHHHHHHHH?HHHH 4AR9|A PF01753.13_zf-MYND_seed 177 92 !Q:0,2|6,30|33,33|36,37|41,51|53,61|65,65|74,74|76,81|83,86 Q:3,5|31,32|34,35|38,40|52,52|62,64|66,73|75,75|82,82|87,91 ?--SSS??---------------------??SS?EE?-TTT-----------S---??----EES?HHHHHTTH-H------H----HHHHH 3OXL|A PF01754.11_zf-A20_seed 53 26 !Q:0,1|3,4|7,8|12,13|20,20 Q:2,2|5,6|9,11|14,19|21,25 ??B?-TT??SSB??TTTTSS?HHHHH 2C7M|A PF01756.14_ACOX_seed 37 203 !Q:0,0|5,5|35,36|46,46|71,75|77,78|94,94|113,115|125,125|129,129|147,149|155,155|159,159|162,163|180,182|186,186|193,194|196,202 Q:1,4|6,34|37,45|47,70|76,76|79,93|95,112|116,124|126,128|130,146|150,154|156,158|160,161|164,179|183,185|187,192|195,195 ?TTSH-HHHHHHHHHHHHHHHHHHHHHHHHHHTTT??HHHHHHTTH-HHHHHHHHHHHHHHHHHHHHHHGG-----G??SHHHHHHHHHHHHHH-HHHHHHHTHHHHHHTTSS--?HHHHHHHHH-HHH-HHHHHHGGGHHHHHHTT???HHHHT?STT?TT??HHHHHHHHHHTSGGGS---SSS?THHHHH--T??????? 1W07|A PF01758.11_SBF_seed 17 225 !Q:14,15|26,28|52,52|57,58|61,79|91,93|105,106|109,109|120,123|139,139|146,155|183,187|192,192 Q:0,13|16,25|29,51|53,56|59,60|80,90|94,104|107,108|110,119|124,138|140,145|156,182|188,191|193,224 HHHHHHHHHHHHHH??GGGGHHHHHS---HHHHHHHHHHHHHHHHHHHHHHH-HHTT??HH-------------------HHHHHHHHHHS???THHHHHHHHTT??HH-HHHHHHHHHH----HHHHHHHHHHHHHHH?GGGHHH----------HHHHHHHHHHHTHHHHHHHHHHHHHHG-----GGGH-HHHTTHHHHHHHHHHHHHHHHHHHTHHHHHHH 3ZUX|A PF01759.16_NTR_seed 103 147 !Q:2,3|9,12|24,32|34,39|54,63|66,69|72,72|81,85|92,94|97,98|112,115|120,120|124,125|128,128|133,135|147,147 Q:0,1|4,8|13,23|33,33|40,53|64,65|70,71|73,80|86,91|95,96|99,111|116,119|121,123|126,127|129,132|136,146 HH--TTSSS----EEEEEEEEEEE-----????S------SEEEEEEEEEEEEE----??----SS??-?TT?EEEEEEEG-----GGTTTS???SS?-EEEEEEETTSEES----SSSS?EEE??SS?EEEE???GGGTTSSSSHH- 4FXG|C PF01761.15_DHQ_synthase_seed 95 359 !Q:4,4|10,10|12,12|18,18|29,33|36,36|60,61|68,68|80,80|97,99|113,113|117,118|133,133|135,139|156,174|176,177|183,188|192,198|207,207|215,219|224,228|244,244|246,250|254,255|267,267|269,269|280,281|287,298|309,316|318,319|322,339|341,341|348,350|357,358 Q:0,3|5,9|11,11|13,17|19,28|34,35|37,59|62,67|69,79|81,96|100,112|114,116|119,132|134,134|140,155|175,175|178,182|189,191|199,206|208,214|220,223|229,243|245,245|251,253|256,266|268,268|270,279|282,286|299,308|317,317|320,321|340,340|342,347|351,356 EEEE?SSGGG?B-HHHHH-HHHHHHHHTT---??TT?EEEEEESHHHHHHHHHHHHHBTT??EEEEEE?SHHHHHHTSSS?EEEEEETTEEEEEEEE???SEEEEEGGGGGGS?HHH--HHHHHHHHHHHHHH-T-?---HHHHHHHHHHHHHHHT-------------------T-?HHHHH------HHH-------HHHHHHHH-HHHHHHH??-??GGGG-----GGTTHHHHHHHHHHH?T-----TTS?-HHHHHHHHHHH-H-HHHHHHTTSS-?HHHHH------------HHHHHHHHTT?-?---?-S??TT----------?------?H-HHHHHH---HTGGGT?? 1NVB|A PF01764.20_Lipase_3_seed 61 256 !Q:4,22|26,26|31,44|47,47|50,59|61,61|73,75|78,102|108,108|120,120|128,131|133,135|156,163|170,170|173,173|176,177|180,183|191,197|199,199|208,219|221,221|225,229|231,236|245,246|250,250|252,252|255,255 Q:0,3|23,25|27,30|45,46|48,49|60,60|62,72|76,77|103,107|109,119|121,127|132,132|136,155|164,169|171,172|174,175|178,179|184,190|198,198|200,207|220,220|222,224|230,230|237,244|247,249|251,251|253,254 EEEE????--?????????-???EEE?HHHH?-------------GG-GT----------T?EEEHHHHHHHH???TT------------------------?TTTSS?HHHHHHHHHHH-HHHHTTT----S?--EEEEEEEETHHHHHHHHHHH--------HHHHTT?SS?TT-?TT????EEEEEES????---B?HHHHHHHH------------T?TTE-----E------EEEEEETT??GGG?S?SS? 1UZA|A PF01765.14_RRF_seed 133 196 !Q:8,9|11,11|14,15|22,22|28,30|32,33|36,39|62,62|76,76|78,81|84,84|86,89|91,91|93,93|95,97|99,99|104,105|107,108|121,121|129,134|149,149|158,159|161,161|196,196 Q:0,7|10,10|12,13|16,21|23,27|31,31|34,35|40,61|63,75|77,77|82,83|85,85|90,90|92,92|94,94|98,98|100,103|106,106|109,120|122,128|135,148|150,157|160,160|162,195 HHHHHHHT??S-BS??GGGGTT?EEESS---S-?EE----EGGGGEEEEEEETTEEEEEESS-GGGHHHHHHHHHH-H----TS-S???-E-E?S---S?EEEE??B??HHHHHHHHHHHH-HHHHHHH------HHHHHHHHHHHHHH-HHHHHHTS--S?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH- 2V46|Y PF01766.12_Birna_VP2_seed 4 453 !Q:0,1|3,4|12,12|16,21|24,27|41,42|46,46|52,52|55,55|67,67|71,72|81,81|84,84|104,104|106,115|125,125|129,129|131,132|141,141|143,143|156,156|161,163|165,165|168,170|173,174|177,181|183,183|185,185|187,189|192,194|197,197|213,215|218,218|233,233|244,244|249,249|264,264|273,273|275,275|278,278|282,282|285,288|296,296|300,301|303,303|314,314|319,320|323,324|348,348|357,358|361,361|376,376|383,385|387,391|410,411|427,433|439,452 Q:2,2|5,11|13,15|22,23|28,40|43,45|47,51|53,54|56,66|68,70|73,80|82,83|85,103|105,105|116,124|126,128|130,130|133,140|142,142|144,155|157,160|164,164|166,167|171,172|175,176|182,182|184,184|186,186|190,191|195,196|198,212|216,217|219,232|234,243|245,248|250,263|265,272|274,274|276,277|279,281|283,284|289,295|297,299|302,302|304,313|315,318|321,322|325,347|349,356|359,360|362,375|377,382|386,386|392,409|412,426|434,438 ??S??HHHHHHH?GGG??????SS????BEEEEEEEEEEEE??TTS?EEEEE?TT?SSSEEEEEEEE?TTS-?EEEEEEEE?SS?GGGTEEEEEEEEEEEEEEE?B??????????EEEEEEESS?GGG?S??STTGGGGS?S?GGGEEEEEETTT?EEEE???S?SS???EE??EE?????S?T-T???EE???SS?EEEEEEEEEEEEEEE???TT?EEEEEEEEEEEESS?EEEEEEEEEE?SSTT-EEEEEEEEEEETTS?EEEEEEEE?S?EE?TTS?EE----EEEEEEE?GGG??S?EEEEEEEEEE-EESS??SS??EEEEEEEEEEEEETTTTSTTTSS?EEEEEEES??TT?EEEEEEEEEEEEEE?TTGGGT???B?????TTHHHHHHHHHHTHHHHT??SEEEHHHHHHHHHHS???????TTTTT?????????????? 1WCD|J PF01767.11_Birna_VP3_seed 5 273 !Q:0,134|138,144|162,162|165,166|172,173|179,181|192,192|194,196|199,201|207,214|227,228|232,235|252,255|271,272 Q:135,137|145,161|163,164|167,171|174,178|182,191|193,193|197,198|202,206|215,226|229,231|236,251|256,270 -----------------------------------------------------------------------------------------------------------------------------??????????HHH-------HHHHHHHHHHHHHHHTT?TT??HHHHH--HTTSS???HHHHHHHHHH?S???TT???TTTTS????????HHHHHHHHHHHH??GGG????HHHHHHHHHHHHHTTT????HHHHHHHHHHHHHHH?? 2R18|A PF01768.11_Birna_VP4_seed 4 282 !Q:0,59|62,62|70,77|81,81|88,99|102,102|111,114|132,133|138,138|142,143|152,152|158,158|160,162|166,168|170,170|181,181|185,185|191,191|194,195|212,213|216,221|223,223|227,228|231,231|239,240|242,242|246,248|258,259|267,267|271,271 Q:60,61|63,69|78,80|82,87|100,101|103,110|115,131|134,137|139,141|144,151|153,157|159,159|163,165|169,169|171,180|182,184|186,190|192,193|196,211|214,215|222,222|224,226|229,230|232,238|241,241|243,245|249,257|260,266|268,270|272,281 ----------------------------------------------------????????EE?HHHHHHH--------HTT?EEEEEE???---------SB?EEEEEEEE?---TTSTTEEEEEEEEEEES??GGGS?GGG??EEEBTTTS?EEETB?S?--BSS???S?EEEEEEEEEE?TTS?EEEEE?SS??BBSSTTHHHHHHHHHT??SB?----?S-SEE??EE?TTSSBEE??S?HHH---HHHHHHTTT??EEESSTT?SEE?SBHHHHHHHH 4IZJ|A PF01769.11_MgtE_seed 17 147 !Q:0,0|27,27|29,29|31,37|54,57|64,65|74,74|76,80|83,84|87,87|104,105|119,120|125,125|142,142|147,147 Q:1,26|28,28|30,30|38,53|58,63|66,73|75,75|81,82|85,86|88,103|106,118|121,124|126,141|143,146 ?SHHHHHHHHHHHHHHHHHHHHHHHTT?S?S-------SSHHHHHHHHHHHHHH----HHHHHH--HHHHHHHH-H-----TS??SS?HHHHHHHHHHHHHHHH--HHHHHHHHHHHTS??GGGS?STTHHHHHHHHHHHHH-HHHH- 2YVX|A PF01771.12_Herpes_alk_exo_seed 14 670 !Q:13,13|28,31|33,36|51,56|64,65|67,94|107,141|151,170|173,174|195,195|217,217|219,225|227,248|267,273|277,309|312,316|319,319|328,330|335,349|361,361|364,366|368,368|370,370|372,372|385,385|400,400|405,406|410,412|415,415|420,420|425,426|428,433|435,436|442,444|456,456|463,470|478,479|481,531|538,539|542,542|559,559|564,578|589,598|602,602|605,605|611,613|615,616|620,620|630,633|636,636|651,651|658,658|662,666 Q:0,12|14,27|32,32|37,50|57,63|66,66|95,106|142,150|171,172|175,194|196,216|218,218|226,226|249,266|274,276|310,311|317,318|320,327|331,334|350,360|362,363|367,367|369,369|371,371|373,384|386,399|401,404|407,409|413,414|416,419|421,424|427,427|434,434|437,441|445,455|457,462|471,477|480,480|532,537|540,541|543,558|560,563|579,588|599,601|603,604|606,610|614,614|617,619|621,629|634,635|637,650|652,657|659,661|667,669 HHHHHHTTSSHHH-HHTSHHHHHHHHSS----S????TTHHHHHHHHHHHH------HHHHHHT??H----------------------------HHHHHHHHTSTT??-------------------------------??SHHHHHHHH--------------------TT??HHHHHHHHHHHHHTTTTGGG?TTHHHHTTTSEEHHHHHHHHT-T???????S?????????????------???HHHHHHHHHHHHHHHTTS-------TTS--------------------------------?EE?????EE?TTTSSEEE???EEES--?-???????????TTSEEEEEEEE?TT???S?T-T?HHHHHHHHHHHS?SHHHHHHHHTTSSS?SEEE??TTB???SS?SEEE?SGGG??S?-????B??GGGHH---HHHHHHTSSSS?EEEEEE?------?TTTTTTB??E---------------------------------------------------EEEEEE??EE?TTSHHHHHHHHHHHHH-HHTT??????---??????EEEEEEEEEE?-------??TTS?SS?EETTE---E??TTS?EEEEEEEEE????HH-HHHHHHHHHHHHHH-HHHHHH?TTS-????TTG 3POV|A PF01773.15_Nucleos_tra2_N_seed 166 81 !Q:13,13|15,15|18,18|20,21|27,29|74,75 Q:0,12|14,14|16,17|19,19|22,26|30,73|76,80 HHHHHHHHHHHHH?S?GG-G??HHHHH---HHHHHHHHHHHHHHTSHHHHHHHHHHHHHHHHHHHHHHHHHHHH--HGGGG 3TIJ|A PF01774.12_UreD_seed 163 426 !Q:6,9|11,11|13,13|16,17|26,26|29,29|35,39|43,71|75,106|109,109|117,117|120,120|125,128|132,132|135,135|146,157|160,160|170,173|175,175|177,178|180,180|183,218|220,228|233,233|242,246|249,258|261,261|263,263|266,266|272,273|277,285|287,287|295,303|306,307|317,317|319,349|355,356|360,380|383,383|391,391|394,401|405,405|418,420 Q:0,5|10,10|12,12|14,15|18,25|27,28|30,34|40,42|72,74|107,108|110,116|118,119|121,124|129,131|133,134|136,145|158,159|161,169|174,174|176,176|179,179|181,182|219,219|229,232|234,241|247,248|259,260|262,262|264,265|267,271|274,276|286,286|288,294|304,305|308,316|318,318|350,354|357,359|381,382|384,390|392,393|402,404|406,417|421,425 EEEEEE??--S?B?TT-?EEEEEEEE?TT?EEEEE?-???EEE??--------------------------?TTS?-------------------------------EE-EEEEEEE?TT?EEEE????EEE?TT?EEEEEEEEEE-----------?TT?EEEEEEEEE---?S?G--G-GT----------------------------------??S--------?SSEE-EEEEEEEE-----TT----------EE-E-EE-EEEEE-?TTT---------S?TTSTTTT---------TT??EEEEEEEES?S-----?--------------------?----HHHHH--HHH---------------------HT?TTEEEEE-EE?-------TTS?EEEEEEESSHHH---HHHHH 3SF5|B PF01775.12_Ribosomal_L18ae_seed 63 199 !Q:0,0|8,12|16,20|36,104|115,117|121,122|126,127|129,129|131,136|138,138|141,143|146,146|153,154|157,158|167,167|186,188 Q:1,7|13,15|21,35|105,114|118,120|123,125|128,128|130,130|137,137|139,140|144,145|147,152|155,156|159,166|168,185|189,198 ?EEEEEEE?????SSS?????EEEEEEESSHHHHHH---------------------------------------------------------------------HHHHHHHHHS???STT??EEE??E-E----??S?SS???EE-EEEEEE??SS??EEEEEEEE?SSHHHHHHHHHHHHHHHH???GGGEEEEEEE 3J39|S PF01776.12_Ribosomal_L22e_seed 35 159 !Q:0,8|10,13|18,19|27,27|29,33|38,43|51,52|57,68|70,72|74,79|81,81|86,87|90,90|98,100|108,115|125,125|135,136|146,149|152,153|155,158 Q:9,9|14,17|20,26|28,28|34,37|44,50|53,56|69,69|73,73|80,80|82,85|88,89|91,97|101,107|116,124|126,134|137,145|150,151|154,154 ?-??---??E----EEEE??HHHHTTS-S??---HHHH------HHHHHHH??BTTB-----------?S???S-----?S?EEEE?-SS?EEEEESS???HHHHHHH--------HHHHHHHHT?TTTEEEEEE--ETTEEEEEE???-SS??S???? 3J39|U PF01777.13_Ribosomal_L27e_seed 42 109 !Q:0,2|5,6|15,16|35,39|46,51|54,55|78,80|84,93|103,103|105,108 Q:3,4|7,14|17,34|40,45|52,53|56,77|81,83|94,102|104,104 ???SS??SHHHHHHT??EEEEEEEEGGGEEEEEEE?-??-GGGTTT------SS--TTTSSSHHHHHHHHHHHHHHHH---HHH----------TTTTTGGGG-S???? 3J39|Z PF01778.12_Ribosomal_L28e_seed 67 198 !Q:6,7|11,11|13,13|15,15|20,26|31,33|36,36|41,42|48,83|85,85|87,89|92,93|96,96|98,98|101,103|106,106|111,117|121,121|123,124|126,126|130,134|136,138|140,141|144,144|146,146|159,161|164,164|170,172|180,192 Q:0,5|8,10|12,12|14,14|16,19|27,30|34,35|37,40|43,47|84,84|86,86|90,91|94,95|97,97|99,100|104,105|107,110|118,120|122,122|125,125|127,129|135,135|139,139|142,143|145,145|147,158|162,163|165,169|173,179|193,197 HHHHHH--TTT?S-S?EEET-------TEEE???SS?SSSB??SSSSS-----------------------------------?S?S???EE--ES?S-SS---SS?EEEE???---?SSS?S?-S?TTT-----T???E--EE?S?THHHHHHHHHHT---TS?STTHH---HHHHHHH-------------HHHHH 3J39|r PF01779.12_Ribosomal_L29e_seed 30 43 !Q:0,6|10,10|18,27|30,32|35,36 Q:7,9|11,17|28,29|33,34|37,42 ???????TTH-HHHHTTS???????--?SS???TT??HHHHHH 3J39|b PF01780.14_Ribosomal_L37ae_seed 55 94 !Q:0,10|15,15|17,17|34,34|36,37|41,41|44,45|57,58|62,63|67,68|74,74|83,93 Q:11,14|16,16|18,33|35,35|38,40|42,43|46,56|59,61|64,66|69,73|75,82 ???????????SSTT?S?HHHHHHHHHHHHHHHS?B??SSS?SS?-EEEEETTEEEE--TTT??EEE??SSSSS?HHHHHHHH?????-????? 1S1I|9 PF01781.13_Ribosomal_L38e_seed 26 83 !Q:0,0|3,5|15,15|19,23|29,36|39,45|51,51|55,55|60,61|74,74 Q:1,2|6,14|16,18|24,28|37,38|46,50|52,54|56,59|62,73|75,82 ?EE???HHHHHHHHS-SSS??---EEEEE------??SS?-----?EEEEE?TTS?EEEE??SSHHHHHTSSSS?TTSEEEEE 3J39|k PF01782.13_RimM_seed 170 121 !Q:19,20|24,26|33,34|40,57|62,66|70,73|81,81|84,85|88,88|97,98|104,104|110,110|113,114 Q:0,18|21,23|27,32|35,39|58,61|67,69|74,80|82,83|86,87|89,96|99,103|105,109|111,112|115,120 EEEEEEEEETTTTEEEEEE?-SSS---GGGGGG??EEEEE------------------ETTE-----EEE----EEEEEEE-EE--TT-EEEEEETT??SHHHH-HTTTT?EE--EEEGGG 3H9N|A PF01783.18_Ribosomal_L32p_seed 171 85 !Q:1,2|5,7|18,31|33,48|51,51|54,55|57,59|66,67|71,74|80,80|82,84 Q:0,0|3,4|8,17|32,32|49,50|52,53|56,56|60,65|68,70|75,79|81,81 S??SS???TTHHHHHHTT-?-----?????-?E----------------EE?SS--S?-?EEETTS??TTT-?--BSSSB?S??? 2ZJQ|Z PF01784.13_NIF3_seed 122 584 !Q:10,10|15,18|21,53|56,58|62,72|76,101|103,104|112,113|123,128|131,133|140,143|145,163|165,166|168,170|173,176|189,189|191,201|203,203|208,209|218,218|226,226|230,234|236,236|238,246|267,267|285,285|305,325|358,359|378,378|384,384|386,389|404,404|406,415|417,424|428,434|436,437|444,448|452,453|459,459|461,462|467,468|475,477|479,480|486,499|507,508|512,516|518,524|526,527|531,532|534,534|544,548|557,557|562,579|581,583 Q:0,9|11,14|19,20|54,55|59,61|73,75|102,102|105,111|114,122|129,130|134,139|144,144|164,164|167,167|171,172|177,188|190,190|202,202|204,207|210,217|219,225|227,229|235,235|237,237|247,266|268,284|286,304|326,357|360,377|379,383|385,385|390,403|405,405|416,416|425,427|435,435|438,443|449,451|454,458|460,460|463,466|469,474|478,478|481,485|500,506|509,511|517,517|525,525|528,530|533,533|535,543|549,556|558,561|580,580 HHHHHHHHHS?GGGS--?-TT-???-----------------------------EE---EES----------?SSS--------------------------B??EEEEESS??HHHHHHHHH------HT-??EEEESS?---S-??----------------S??S???TT----SHHHHHHHHHHH-T-----------T?EEEE??HHHHHSTT-SHHHHHH-HHT-----T?E---------EEEEEEEEEEEEEEEEEEEE?HHHHHHHHHHHHHTTTT?BTTEEEEEEEEEEEEEEEE?????-------?????????EEEEEEEEEEEEEGGGHHHHHHHHHHHSSSSS??EEEEEEEEEEEEEEEEEE-EEEEE-E----EEHHHHHHHHHHHT-T?---------S?------?EEE-------S-?TTSEEE-----EEE--EEEEE?G--GGHH--HHHHTT?--S--EEEEE??-----------?HHHHHHH--HHH-----T------?E--EEE??G-GGGGHHHHH-----HHHHHHHH-HHHT------------------T??? 1NMP|A PF01786.12_AOX_seed 60 494 !Q:0,3|9,9|11,12|14,19|42,42|44,139|143,145|176,181|186,188|190,252|276,280|305,305|334,334|337,337|339,340|342,346|348,349|358,359|361,361|363,466|482,483|485,485 Q:4,8|10,10|13,13|20,41|43,43|140,142|146,175|182,185|189,189|253,275|281,304|306,333|335,336|338,338|341,341|347,347|350,357|360,360|362,362|467,481|484,484|486,493 ????HHHHT-T??B??????SHHHHHHHHHHHHHHHHHHHHT?T------------------------------------------------------------------------------------------------TSS???HHHHHHHHHHHHHHHTSHHHHHHHHHHHHH------HHHT???T---------------------------------------------------------------TSHHHHHHHHHHHHHHHHHHHHH?-???HHHHHHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHHHHHHHHHHHH-TS-S??S---??S??HHHHHHTT??T-T------------------------------------------------------------------------------------------------------??HHHHHHHHHHHHHHH--H-HHHHHHHH 3VV9|A PF01788.12_PsbJ_seed 25 42 !Q:0,5|8,8|10,10|40,41 Q:6,7|9,9|11,39 ???--?SS?S?HHHHHHHHHHHHHHHHHHHHHHTTTSSSS?? 3PRR|J PF01789.11_PsbP_seed 30 216 !Q:0,22|27,28|30,30|41,41|44,48|50,53|62,62|65,65|77,77|79,79|81,83|89,89|103,124|132,133|137,137|141,141|149,171|212,212|215,215 Q:23,26|29,29|31,40|42,43|49,49|54,61|63,64|66,76|78,78|80,80|84,88|90,102|125,131|134,136|138,140|142,148|172,211|213,214 --?????????????????????EEEE--E?SSEEEEEETT?EE?????S----TTEEEEEE?TT?TTSEEEEEEEE?S?S---SGGGG?SHHHHHHHTGGGG??????????????????????EEEEEEE??EET-TEE?EEEEEEE?????--???------------?EEEEEEEEEETTEEEEEEEEEEHHHHHTTHHHHHHHHHHH?EE? 2XB3|A PF01791.4_DeoC_seed 26 316 !Q:6,7|20,20|22,24|28,29|44,50|58,58|70,70|72,77|79,81|85,85|87,87|90,91|97,100|102,102|104,106|108,109|118,118|128,128|132,132|152,153|157,158|163,163|167,168|172,173|200,202|207,208|211,211|219,219|222,224|226,226|241,241|244,253|255,259|263,263|266,270|283,285|289,304|309,309 Q:0,5|8,19|21,21|25,27|30,43|51,57|59,69|71,71|78,78|82,84|86,86|88,89|92,96|101,101|103,103|107,107|110,117|119,127|129,131|133,151|154,156|159,162|164,166|169,171|174,199|203,206|209,210|212,218|220,221|225,225|227,240|242,243|254,254|260,262|264,265|271,282|286,288|305,308|310,315 EEEEEE??SHHHHHHHHHHH?S???HHH--HHHHHHHHHHHHTT-------TSSEEEE?TTTHHHHHHSS?S------S???EEE?B?SS??SSSTT????B?T---T??HHHHHTTT?SEEEEEEEE?TTS?HHHHHHHHHHHHHHHHHHH--HTT??EEEE-EEE??SSS??TTSHHHHHHHHHHHHHHHHHHTSGGG???EEEE??SS?GGGBTTT?SS???B?HHHHHHHHHHHHHT?SS?---------E-----EEE?TT?---?HHHHHHHHHHHH---HHT???------------?EEEE?HHHHTH 1OJX|A PF01793.11_Glyco_transf_15_seed 107 514 !Q:0,9|11,47|52,54|58,108|115,117|121,123|142,143|145,147|155,157|168,169|172,175|178,186|190,191|197,198|202,205|216,216|226,226|249,249|255,256|259,259|262,262|264,267|269,269|279,280|285,285|289,292|296,296|308,309|312,312|315,317|320,320|322,322|324,325|330,330|332,333|335,419|424,426|430,430|445,459|461,462|480,482|496,496|503,503|506,507 Q:10,10|48,51|55,57|109,114|118,120|124,141|144,144|148,154|158,167|170,171|176,177|187,189|192,196|199,201|206,215|217,225|227,248|250,254|257,258|260,261|263,263|268,268|270,278|281,284|286,288|293,295|297,307|310,311|313,314|318,319|321,321|323,323|326,329|331,331|334,334|420,423|427,429|431,444|460,460|463,479|483,495|497,502|504,505|508,513 ??????????H-------------------------------------HHHH---GGG?????---------------------------------------??---??EEEEEE??-GGG---HHHHHHHHHHHHHHTTTT--S???EEEEESS???HHHHHHHHHH?-SS?---EE---------EEE??GGGSS??TTS---?HHHHHHHHHH-HTTTSTTTT?HHHHHHHHHHHHTGGGSGGGTT?SEEEE??TT?EE?S??-?S?HHHHHHHTT??EEES?EEE-?-?GGG?TTHHHHHHHHH--HH?GG---GS?T-T??HHHH?S--S-------------------------------------------------------------------------------------TTSS???EEE?SSSEEEEHHHHTSH---------------H--HHHHHHHHHHHTHHHHS???HHHHHHHHHHHHS?GGGEEE?TT??EEETTE 1S4O|A PF01795.14_Methyltransf_5_seed 16 368 !Q:0,5|16,29|32,35|41,42|55,56|59,59|67,67|72,72|78,84|93,95|107,108|110,122|125,125|133,133|135,136|142,142|146,148|152,154|157,159|161,161|166,168|176,177|190,191|207,212|215,217|231,252|288,288|312,335|343,346|353,353|359,359|367,367 Q:6,15|30,31|36,40|43,54|57,58|60,66|68,71|73,77|85,92|96,106|109,109|123,124|126,132|134,134|137,141|143,145|149,151|155,156|160,160|162,165|169,175|178,189|192,206|213,214|218,230|253,287|289,311|336,342|347,352|354,358|360,366 ??????TTTHHHHHHT?-----------??TT?---EEEES??TTSHHHHHHHTT??TT?EEEEEES?HHHH-HHHTT??----?TTEEEEES?--GGGHHHHHHHT--T------------?TT?EEEEEEE?S??HHHHH?GGG???SSS?-?BS???S?TTSS?-?HHHHHHH??HHHHHHHHHHHH??TTHHHHHHHHHHHHH------HS???BHHHHHHHHHHHS????-----??---------??TTHHHHHHHHHHHHTHHHHHHHHHHHHHHHEEEEE-EEEEEESSHHHHHHHHHHHHHTT???-????????????????????EEEEEEE?-??HHHHHH?GGGTT?EEEEEEE? 1N2X|A PF01797.11_Y1_Tnp_seed 178 141 !Q:3,3|9,11|13,14|16,17|20,21|23,23|26,26|36,36|45,45|50,52|66,67|71,72|90,91|99,99|104,107|109,112|114,114|116,116|124,129 Q:0,2|4,8|12,12|15,15|18,19|22,22|24,25|27,35|37,44|46,49|53,65|68,70|73,89|92,98|100,103|108,108|113,113|115,115|117,123|130,140 EEE?EEEEE---E??S??TT?-S?TH-HHHHHHHHH-HHHHHHHT?EEEE---EEEETTEEEEEEE??TTS-?HHHHHHHHHHHHHHHHH--HTTHHHH-HTTT----S??--S?S?EEEEEEB--??-?HHHHHHHHHHS 2VJU|A PF01798.13_Nop_seed 16 157 !Q:30,30|38,38|58,59|68,68|78,82|84,88|90,90|103,103|129,132|135,140|156,156 Q:0,29|31,37|39,57|60,67|69,77|83,83|89,89|91,102|104,128|133,134|141,155 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?HHHHHHH?HHHHHHHHHHHTSHHHHHT??HHHHHHTT?HHHHHHHHH-----T?????S?SGGGGSHHHHTS?GGGHHHHHHHHHHHHHHHHHHHHHT????HH------HHHHHHHHHHHHHHH? 3ID5|A PF01799.15_Fer2_2_seed 157 127 !Q:0,0|3,4|7,20|22,22|24,25|29,30|41,42|45,45|61,63|65,83|85,85|87,94|98,98|103,103|105,105|108,112|116,116 Q:1,2|5,6|21,21|23,23|26,28|31,40|43,44|46,60|64,64|84,84|86,86|95,97|99,102|104,104|106,107|113,115|117,126 ?GG--GS--------------S-B--TTB??HHHHHHHHHT??SS?SSHHHHHHHHHHHHH---H------------------?S-S?------?HHH-HHHH-T-TT--???SSS?SHHHHHHHHH 1DGJ|A PF01804.13_Penicil_amidase_seed 21 1013 !Q:2,2|9,9|11,12|17,17|49,49|55,55|57,67|84,89|99,99|103,109|126,131|133,133|138,138|145,153|155,156|167,167|175,203|210,274|276,278|283,297|305,305|313,314|326,326|330,330|338,339|342,342|352,352|355,356|361,361|370,375|381,382|385,388|396,396|401,402|404,405|413,415|419,420|428,429|431,431|439,439|442,456|467,469|473,473|481,481|490,490|492,492|496,497|499,499|501,501|511,511|517,517|519,520|522,526|529,530|537,541|546,554|558,561|563,565|569,571|573,573|578,578|580,586|596,596|599,599|604,604|606,607|612,612|615,615|618,628|641,642|644,652|654,654|664,666|668,668|677,691|700,707|710,710|723,724|727,728|731,731|736,744|759,761|764,766|770,799|806,806|812,812|815,824|837,854|861,877|881,882|889,898|908,920|922,922|924,924|928,928|935,938|942,942|944,944|950,950|953,955|960,961|963,963|965,965|974,974|976,977|981,981|995,996|999,1001 Q:0,1|3,8|10,10|13,16|18,48|50,54|56,56|68,83|90,98|100,102|110,125|132,132|134,137|139,144|154,154|157,166|168,174|204,209|275,275|279,282|298,304|306,312|315,325|327,329|331,337|340,341|343,351|353,354|357,360|362,369|376,380|383,384|389,395|397,400|403,403|406,412|416,418|421,427|430,430|432,438|440,441|457,466|470,472|474,480|482,489|491,491|493,495|498,498|500,500|502,510|512,516|518,518|521,521|527,528|531,536|542,545|555,557|562,562|566,568|572,572|574,577|579,579|587,595|597,598|600,603|605,605|608,611|613,614|616,617|629,640|643,643|653,653|655,663|667,667|669,676|692,699|708,709|711,722|725,726|729,730|732,735|745,758|762,763|767,769|800,805|807,811|813,814|825,836|855,860|878,880|883,888|899,907|921,921|923,923|925,927|929,934|939,941|943,943|945,949|951,952|956,959|962,962|964,964|966,973|975,975|978,980|982,994|997,998|1002,1012 SS?EEEEET-T??EEEE?SSHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?HHHHH?G-----------GGHHHHHHHHHTTHHH------HHHHHHHTS?HHH-------HHHHHHHHHHHHHHHH------H?GGGS?GGGGGG?--------S??HHHHHHHHHH-HHHHTTT??---------------------------HHHHTT-----------------------------------------------------------------S???HHHH??-------------EEEEEEE?GGGBSSS??EEEEEEEEESS?GGG?EEEEEEE?-SS?EEEEEEETT?SS?-SEEE?SSEEEEEE??????EEEEE??EE----TTEEEET-TEEE??B??EEEEEEE?--TTS-?EEEEEEE??B?SSSBEEE?TT?-------------?EEEEEETTTT???HHH-HHHHHHT?SSHHHHHH-H-HTT??S?S?EEEEEETTS?EEEEE?S??B??---SS??HHHHHS----?EESS?--------GGG????B??-GGG---S?EEES?T-------TSEEEESSS?TT?SSSS?S??GGGS?TT-SS??????-----HHHHHHHHHHHT??S---------B?HHHHHHHHT?-?B?HHHHHHHH---------------HHHHHHHH--------SS?HHHHHHHHHHHH??SB??TT?SSHH---------HHHHHHHHHHTTTT???TT---EEE???---------------------------TTSTTT?SEEES?HH----------HHHHHHHHHHHH------------------HHHHHS-----------------SSS??HHHHBE----------EEETTEEEE?----------??B?G-GGT?SSBEEE????TTS?B?EEEEE?EE---EEEE??S-S?EEEEEETT?S??STT?SSSSSSHHHHHTT??EE???SHHHHHHHEEE 1GK1|A PF01805.15_Surp_seed 64 64 !Q:15,15|21,24|31,32|35,36|44,45|48,48 Q:0,14|16,20|25,30|33,34|37,43|46,47|49,63 HHHHHHHHHHHHHHH?THHHH----HHHHHS--TT?-GGGGGGS--TT-STTHHHHHHHHHHHH 4DGW|B PF01806.12_Paramyxo_P_seed 3 248 !Q:0,2|21,21|28,30|42,43|110,110|113,247 Q:3,20|22,27|31,41|44,109|111,112 ???HHHHHHHHHHHHHTTSSS?HHHHTT???HHHHHHHHHHT??SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGGG?SS??------------------------------------------------------------------------------------------------------------------------------------- 1EZJ|A PF01807.15_zf-CHC2_seed 19 100 !Q:1,1|12,13|22,22|24,25|32,32|36,37|41,42|45,46|62,63|66,66|77,78|92,94|98,99 Q:0,0|2,11|14,21|23,23|26,31|33,35|38,40|43,44|47,61|64,65|67,76|79,91|95,97 S?HHHHHHHHHH??HHHHHTTT-S??EEETTE-EEE??SSS??SS??EEEETTTTEEEETTT??EE?HHHHHHHHHT??HHHHHHHHHHHHT???GGG?? 1D0Q|A PF01808.13_AICARFT_IMPCHas_seed 9 375 !Q:7,7|11,12|31,32|63,86|96,96|103,105|110,110|115,121|129,132|156,156|172,176|185,185|192,193|195,195|221,221|223,223|233,242|244,244|252,252|254,254|265,265|270,270|276,276|279,282|298,306|312,313|315,315|318,323|341,341|344,344|358,358|360,360 Q:0,6|8,10|13,30|33,62|87,95|97,102|106,109|111,114|122,128|133,155|157,171|177,184|186,191|194,194|196,220|222,222|224,232|243,243|245,251|253,253|255,264|266,269|271,275|277,278|283,297|307,311|314,314|316,317|324,340|342,343|345,357|359,359|361,374 HHHTTTT?EEE??GGGHHHHHHHHHSSSSSS??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?-----------------------BTTTEEEES?SSSTTS??-EEEE?SSSS------?SEEEEES?-??HHHHHHHHHHHHHHHHHHHHHSS?EEEEEETTEEEEEEE?????HHHHHHTT?GGGGGG??H-HHHHHHHHTTTTTTTTTTEEEEESS?B?HHHHHHHHT----------S?EEEEEES?B?HHHHHHHHTH-HHHT?EEEEE?SS????SEEEEEETTEEEEEE??---????SGGGG??B?SS???-??TTHHHHHHHHHHHHHTS?SS?EEEEETTEEEEEE?S?SSHHHHHHHHHHHH 4A1O|A PF01812.15_5-FTHF_cyc-lig_seed 24 243 !Q:10,10|16,16|34,34|40,41|45,52|54,59|63,65|67,68|79,79|91,110|119,120|128,128|130,130|134,142|144,146|149,152|159,166|172,173|178,178|181,182|185,185|189,189|201,201|203,203|206,207|213,214|221,227|229,231|233,236|241,242 Q:0,9|11,15|17,33|35,39|42,44|53,53|60,62|66,66|69,78|80,90|111,118|121,127|129,129|131,133|143,143|147,148|153,158|167,171|174,177|179,180|183,184|186,188|190,200|202,202|204,205|208,212|215,220|228,228|232,232|237,240 HHHHHHHHHH-HHHTS?HHHHHHHHHHHHHHHHT?HHHHH?-SEE--------E?????-TTS???H--HHHHHHHHTT?EEEEEEEETTT--------------------TEEEEEEE??TTGGGGS?B?TTS--------?B???TT????BGGGTT------??SEEEE??SEEE-TT??EE?SSS?HHHHHHHHHTT-T?SS??EEEEE??GGGEES--?????T---T????SEEE?? 3HY6|A PF01813.12_ATP-synt_D_seed 114 235 !Q:49,49|61,66|76,84|93,93|104,154|230,230|234,234 Q:0,48|50,60|67,75|85,92|94,103|155,229|231,233 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHHHH??--??HHHHHHHTT????--???EEEEEEEE-TTEEEEEEEE????-------------------------------????????????????HHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHH? 3VR4|G PF01814.18_Hemerythrin_seed 189 215 !Q:0,0|18,22|32,39|42,44|52,52|66,68|81,86|88,92|98,114|118,118|128,129|132,136|143,143|156,175|178,178|206,207 Q:1,17|23,31|40,41|45,51|53,65|69,80|87,87|93,97|115,117|119,127|130,131|137,142|144,155|176,177|179,205|208,214 ?HHHHHHHHHHHHHHHHH-----HHHHHHHHH--------HH???HHHHHHH-HHHHHHHHHHHTH---HHHTHHHHHHHH------T-----HHHHH-----------------TTT?HHHHHHHHH--HH-----HHHHHH-HHHHHHHHHTGG--------------------GS?HHHHHHHHHHHHHHHHHHHHHHHHHHH--HTHHHHH 1A7E|A PF01815.11_Rop_seed 12 66 !Q:0,1|19,19|31,34|59,65 Q:2,18|20,30|35,58 ??HHHHHHHHHHHHHHHHH-HHHHHHHHHTT---?HHHHHHHHHHHHHHHHHHHHHHHH??-???? 1QX8|A PF01816.12_LRV_seed 56 28 !Q:10,11|13,13|23,25 Q:0,9|12,12|14,22|26,27 HHHHHHHHHH--S?TGGGGGGTT--?SS 1LRV|A PF01817.16_CM_2_seed 101 93 !Q:32,36|38,40|42,43|45,45|59,64|68,70|86,92 Q:0,31|37,37|41,41|44,44|46,58|65,67|71,85 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----T??-S??H-HHHHHHHHHHHHH??----SSS?--HHHHHHHHHHHHHHT??????? 1CSM|A PF01818.12_Translat_reg_seed 11 122 !Q:0,0|5,5|34,34|58,63|83,83|86,86|89,89|92,97|100,100|103,104|119,121 Q:1,4|6,33|35,57|64,82|84,85|87,88|90,91|98,99|101,102|105,118 ?EEEE?SSTTHHHHHHHHHHTEEEEETTTTEEEE?EEEEEETTEEEEEEHHHHHHHTT??????HHHHHHHHHHHHHHHHTTS?EE?SS?EE??????SS?EE??TTTGGGSEEEETTT??? 1REG|X PF01819.12_Levi_coat_seed 5 133 !Q:0,4|15,15|39,40|44,45|53,60|74,81|96,96|99,100|105,105|128,132 Q:5,14|16,38|41,43|46,52|61,73|82,95|97,98|101,104|106,127 ?????EEEEEESTTS?EEEEEEEEEEETTTTEEEEEETT??GGG??EEEEEEE????????EEEEEEEEEEEEE????????EEEEEEEEEEEEEE?TT??HHHH-HHHHHHHHHHHHSHHHHHHHTS????? 1FR5|A PF01820.16_Dala_Dala_lig_N_seed 176 169 !Q:2,3|10,16|30,35|37,38|45,50|53,53|56,57|60,62|67,125|135,135|141,142|146,147|151,152|163,164 Q:0,1|4,9|17,29|36,36|39,44|51,52|54,55|58,59|63,66|126,134|136,140|143,145|148,150|153,162|165,168 EE--EEEEEE???????HHHHHHHHHHHHS----?-T--TTEEEE------EE-EE?-TT?-?EEEE?????????????????---???????????????????????---------------?TTHHHHHHT?SEEEE??EET--TEE??HHHHHHHHHT??BSSS 1EHI|A PF01821.13_ANATO_seed 65 47 !Q:7,8|10,11|13,15|24,33|35,35|47,47 Q:0,6|9,9|12,12|16,23|34,34|36,46 HHHHTTS??T--T???HHHHGGGB---------?S?HHHHHHHHHHH- 4FXG|B PF01823.14_MACPF_seed 69 368 !Q:0,7|14,20|22,23|44,47|52,59|61,61|65,69|76,77|80,82|86,114|123,123|143,149|159,160|165,172|182,209|216,216|221,222|225,229|239,240|243,266|277,277|279,280|287,323|328,331|341,343|346,352|362,364 Q:8,13|21,21|24,43|48,51|60,60|62,64|70,75|78,79|83,85|115,122|124,142|150,158|161,164|173,181|210,215|217,220|223,224|230,238|241,242|267,276|278,278|281,286|324,327|332,340|344,345|353,361|365,367 ????????TTGGGT-------T??STTEEEEEEEEEEEEEEEEE---?SSSB?-------B?HHH-----HHHHHT??SS-??HHH-----------------------------HHHHHHHH?SEEEEEEEEEEEEEEEEEE-------EHHHHHHTT??HHHH--------HHHHHHTTT???----------???????????????TTTTTT?SHHH--HH-----HTTEEEEEE??BS??????????-------???????HHHHHHHGGG-S?-EEEEEE-------------------------------------EEEG----GGGGGGBTT???HH-------HHHHHHHHH---HHH 2QQH|A PF01825.16_GPS_seed 139 95 !Q:9,19|22,22|26,27|30,31|35,35|38,38|42,69|72,74|76,76|83,86|88,88|95,95 Q:0,8|20,21|23,25|28,29|32,34|36,37|39,41|70,71|75,75|77,82|87,87|89,94 EEEEEEEEE??-----????TT?EEE-?TT--EEE-EE-EET----------------------------TE---E-EEEESS---?S-EEEEEE- 4DLO|A PF01826.12_TIL_seed 167 100 !Q:0,4|11,11|14,15|17,19|22,25|28,28|30,39|42,50|53,55|59,60|62,65|67,70|72,74|77,78|80,81|86,90|95,95|99,99 Q:5,10|12,13|16,16|20,21|26,27|29,29|40,41|51,52|56,58|61,61|66,66|71,71|75,76|79,79|82,85|91,94|96,98 ?-?--TTEEEE-EE--E?--TT-???SS?S????------SS---------SS--?EEE--E----E----E--?TT-?E--EETT-----TEEE?GGG? 1ATA|A PF01828.12_Peptidase_A4_seed 22 244 !Q:2,2|9,13|15,15|17,17|27,28|33,33|36,56|65,65|68,68|70,71|73,76|86,90|94,94|105,106|109,109|112,115|118,118|142,143|150,150|152,154|156,161|169,170|173,174|178,178|180,180|183,184|186,186|191,191|202,202|207,208|212,212|216,217|219,219|222,223|237,237|243,243 Q:0,1|3,8|14,14|16,16|18,26|29,32|34,35|57,64|66,67|69,69|72,72|77,85|91,93|95,104|107,108|110,111|116,117|119,141|144,149|151,151|155,155|162,168|171,172|175,177|179,179|181,182|185,185|187,190|192,201|203,206|209,211|213,215|218,218|220,221|224,236|238,242 EE?EEEEEE-----E?S?EEEEEEEEE??EEES?TT?--------------------EEEEEEEE?SS-S??S?---EEEEEEEEE-----TTS?EEEEEEEETS??EE?SS????TT?EEEEEEEEEETTEEEEEEEETTT??EEEEEE?S-??S??????EEEEEEE??EE??SSS?S?EE??B?EEES?EEEEEEEEEE-TTEE??GGG?EEE??E-ET--TEESEEEEEETTE-EEEEE? 2IFW|A PF01829.11_Peptidase_A6_seed 3 372 !Q:0,10|22,23|27,31|33,35|38,39|53,53|57,61|71,71|73,73|80,83|91,94|97,98|105,105|113,113|118,118|138,138|140,140|144,146|154,155|157,158|167,168|171,171|173,174|190,191|194,194|202,202|208,208|214,216|219,220|223,224|228,228|231,232|237,238|244,246|250,256|259,259|268,268|271,272|288,288|297,297|300,304|319,319|323,323|348,371 Q:11,21|24,26|32,32|36,37|40,52|54,56|62,70|72,72|74,79|84,90|95,96|99,104|106,112|114,117|119,137|139,139|141,143|147,153|156,156|159,166|169,170|172,172|175,189|192,193|195,201|203,207|209,213|217,218|221,222|225,227|229,230|233,236|239,243|247,249|257,258|260,267|269,270|273,287|289,296|298,299|305,318|320,322|324,347 ???????????HHHHHHHHHHH??TTS?????S???SS??SEEEEEEEEEEEE-EEE?----TTEEEEEEE?S?TTEEEE----EEEEETT????TT?-EEEEEE?TTHHHHH?SSTT?GGGTEEEEEEEEEEEEEEE?S?TTT???EEEEEEE??E--EEEEEEEE??SS?E--EEEEEEEESGGGGGS??SS?EEEEGGG?EEEEE?BSSSS???EE??BS??EES?TT??HHHH??SSEEE???TTT???????SB?EEEEEEEE?TT??EEEEEEEEEEEEEEE?TTSSSGGG?EE?????HHHHHHHHHHHHHS?SEE?HHHHHTHHHHHHHHHHHHHHHHHH???????????????????????? 1NOV|A PF01832.15_Glucosaminidase_seed 162 209 !Q:11,11|14,15|17,17|23,24|33,38|43,47|54,55|58,59|62,71|77,78|83,87|106,107|120,120|125,126|129,130|135,137|139,140|145,145|148,150|157,160|168,173|176,179|181,188|200,202|205,205 Q:0,10|12,13|16,16|18,22|25,32|39,42|48,53|56,57|60,61|72,76|79,82|88,105|108,119|121,124|127,128|131,134|138,138|141,144|146,147|151,156|161,167|174,175|180,180|189,199|203,204|206,208 HHHHHHHHHHH-TT??H-HHHHH--HHHHHHTT------TTST-----TTSTTT??TT??BS---------?BTTBE--EEEE-----EEEEETTTEEEEEEEEEE??SSHHHHHHHHHH-HHHH??TT?-TTTT---G--GGST-TT--?SSHHHH----HHHHBTT------TB----S------?-TTHHHHHHHHH---HH-TTG 3K3T|A PF01833.19_TIG_seed 131 166 !Q:0,0|2,2|8,13|17,17|19,21|23,23|30,31|33,59|62,63|72,73|76,87|89,90|95,111|115,116|118,131|134,134|142,142|145,153|155,155|157,159 Q:1,1|3,7|14,16|18,18|22,22|24,29|32,32|60,61|64,71|74,75|88,88|91,94|112,114|117,117|132,133|135,141|143,144|154,154|156,156|160,165 ?E-EEEEE--?---SEE?T---T?EEEEEE--E??------------------------?SS??EEEETTEE??EE------------E??SSEE-----------------EEE??S??------------SE-EEEEEEE?TT---------S?B???EEEEEE 8CGT|A PF01834.11_XRCC1_N_seed 3 155 !Q:0,1|3,4|13,15|19,19|25,25|29,31|34,34|39,39|54,55|64,64|73,73|77,83|87,87|96,96|98,98|106,106|108,110|115,115|120,120|137,138|140,141|144,145|154,154 Q:2,2|5,12|16,18|20,24|26,28|32,33|35,38|40,53|56,63|65,72|74,76|84,86|88,95|97,97|99,105|107,107|111,114|116,119|121,136|139,139|142,143|146,153 ??B??EEEEEEES???SSS?GGGGS?GGG???EE?SSTT?SEEEEEEEEEEEEE??EEEEEEEB?SEEEEEEE?STT?----??GGG?EEEEEEEE?S?HHHHHHT?S???EEEE?TTTS?HHHHHSEEEEEEEEEE??S??SS??EEEEEEEE? 3K77|A PF01835.14_A2M_N_seed 175 155 !Q:7,7|11,11|22,23|26,26|30,57|60,62|69,69|75,75|81,83|86,87|91,92|94,95|99,99|102,103|106,108|119,141 Q:0,6|8,10|12,21|24,25|27,29|58,59|63,68|70,74|76,80|84,85|88,90|93,93|96,98|100,101|104,105|109,118|142,154 EEEEEES?SEE?TTSEEEEEEE--EE?TTS?----------????------------?EE---EEEEET-TEEEE-EEEEE--?TT--TTT--S??EEE-EE??SS???EEEEEEEEET-----------------------TEEEEEEEEEEEE 4FXG|A PF01839.18_FG-GAP_seed 470 62 !Q:8,11|16,17|26,36|40,45|48,49|53,56 Q:0,7|12,15|18,25|37,39|46,47|50,52|57,61 TTSEEEEE--??SSSS??EEEEEETT----------?EEE?-----TT??EEE--??EEEEE 4G1E|A PF01840.12_TCL1_MTCP1_seed 8 127 !Q:0,8|10,10|13,14|20,20|24,24|30,31|40,40|44,44|46,61|67,76|81,81|83,83|86,86|88,88|92,92|96,96|103,103|110,110|116,116|123,126 Q:9,9|11,12|15,19|21,23|25,29|32,39|41,43|45,45|62,66|77,80|82,82|84,85|87,87|89,91|93,95|97,102|104,109|111,115|117,122 ?????????B?SS??SBEEE?SSS?EEETT??EEEEEEEE?SSS?E----------------EEEEE??????????STTT?S?SS?S?EEE?TTS?EEETTS?EEEEEE?BBSSS?BEEEEE???? 1JNP|A PF01841.14_Transglut_core_seed 87 240 !Q:7,11|15,16|20,21|33,39|45,55|59,60|63,72|79,84|86,86|88,92|94,95|112,114|124,154|156,172|175,176|178,197|203,206|210,225|229,233|238,238 Q:0,6|12,14|17,19|22,32|40,44|56,58|61,62|73,78|85,85|87,87|93,93|96,111|115,123|155,155|173,174|177,177|198,202|207,209|226,228|234,237|239,239 HHHHHHH-----HTT??SHH--HHHHHHHHHHH-------HHSEE?----------TTS??TT??--------HHHHHH------H?E-----E-?HHHHHHHHHHHHHHTT?-?EEEEEEEET-------------------------------T----------------?SS??E--------------------EEEEE----EEE----------------TTE-----EEEE?T 2QSH|A PF01842.20_ACT_seed 180 81 !Q:4,6|8,8|12,15|31,33|41,41|43,43|45,52|64,64 Q:0,3|7,7|9,11|16,30|34,40|42,42|44,44|53,63|65,80 EEEE---E-EEE-??-TTHHHHHHHHHHTTT???SEEEEEE?S?S--------SEEEEEEEEES?HHHHHHHHHHHHHSTT 3C20|A PF01843.14_DIL_seed 56 117 !Q:20,20|24,27|37,37|52,52|56,57|76,78|83,83|92,92|94,96|99,99|110,112 Q:0,19|21,23|28,36|38,51|53,55|58,75|79,82|84,91|93,93|97,98|100,109|113,116 HHHHHHHHHHHHHHHHHHHH?GGG---?SHHHHHHHH-HHHHHHHHHHHHTT?TTS--SHHHHTHHHHHHHHHTTS-??SSHH-HHHHHHHH?T---TS?HHHHHHHHHH???SSTT 3MMI|A PF01844.18_HNH_seed 92 68 !Q:0,0|2,3|6,7|9,10|13,20|29,29|32,35|37,38|40,42|44,48|59,59 Q:1,1|4,5|8,8|11,12|21,28|30,31|36,36|39,39|43,43|49,58|60,67 ?T--TT??B??GG--------GEEEEESS?GG----G--T???S-----TTTEEEEEHH-HHHHHHHS 4H9D|A PF01845.12_CcdB_seed 12 107 !Q:0,0|7,9|16,17|22,22|24,24|44,53|55,55|59,59|68,68|72,72|80,83|88,88|105,106 Q:1,6|10,15|18,21|23,23|25,43|54,54|56,58|60,67|69,71|73,79|84,87|89,104 ?TTEEEE???TTTTTT??EEEE?S?GGGTTSSEEEEEEEEEGGG???-??????S?EEE-ETTEEEEE?GGG?EEEEGGG?-??EEEE?GGGHHHHHHHHHHHHH?? 3VUB|A PF01846.14_FF_seed 149 78 !Q:7,7|15,20|23,33|36,38|43,44|47,47|54,55|58,65|70,70 Q:0,6|8,14|21,22|34,35|39,42|45,46|48,53|56,57|66,69|71,77 HHHHHHH-HHHHHTT----??TT?---------?HH---HHHH--HH-TTSTHH--HH?-----??HHHH-HHHHHHH 2LKS|A PF01847.11_VHL_seed 2 156 !Q:0,12|25,25|32,32|36,36|40,42|44,44|47,47|57,57|67,68|70,70|77,77|79,88|95,99|113,113|121,121|123,123|133,135|140,155 Q:13,24|26,31|33,35|37,39|43,43|45,46|48,56|58,66|69,69|71,76|78,78|89,94|100,112|114,120|122,122|124,132|136,139 ?????????????EEEEEEEEESSS?EEEEEE?TTS?EEE???B?TT?EEEEEEETT?EEEEEETTT??B?EETTBS?B??????????EEEEEE?????HHHHHHHHHHTTS?GGGGTTS?S?HHHHHHHHS???HHHH???????????????? 4AWJ|C PF01849.13_NAC_seed 91 66 !Q:0,14|18,21|27,28|31,31|39,39|49,49|56,57|60,60 Q:15,17|22,26|29,30|32,38|40,48|50,55|58,59|61,65 -------????????EEE????EEEEE?-SS-EEEEEES?EEEEEEETT-EEEEEE--ES?EEEEE 1TR8|A PF01850.16_PIN_seed 170 202 !Q:3,3|12,23|27,28|39,39|41,46|57,58|68,90|92,92|114,114|117,122|139,144|147,150|161,167|172,172|174,178|181,183|185,186|188,193|200,201 Q:0,2|4,11|24,26|29,38|40,40|47,56|59,67|91,91|93,113|115,116|123,138|145,146|151,160|168,171|173,173|179,180|184,184|187,187|194,199 EEE?HHHHTGGG------------SSS??HHHHHHHHHS?G------GGEEEEHHHH--HHHHHHHHT----------------------?S?HHHHHHHHHHHHHTTGGGGTT?EE?---??HHHHHHHHHHHHHHHT------TT????HHHHHHHHHH-------HHHT?E-----EE-?-S??H------HHHHTT?? 3DBO|B PF01851.17_PC_rep_seed 157 43 !Q:12,12|14,15|17,19|27,28|31,31|34,35 Q:0,11|13,13|16,16|20,26|29,30|32,33|36,42 HHHHHHHHHTSS-S??H---HHHHHHH--HH-TS-?SSHHHHH 4BGR|N PF01852.14_START_seed 18 259 !Q:17,17|20,20|25,30|32,32|36,36|43,43|45,53|56,56|68,68|71,71|84,84|89,89|92,92|94,97|105,105|109,115|124,130|132,134|146,153|156,156|160,161|164,166|170,176|182,182|185,185|187,187|200,208|217,217|220,221|224,227|246,247|253,258 Q:0,16|18,19|21,24|31,31|33,35|37,42|44,44|54,55|57,67|69,70|72,83|85,88|90,91|93,93|98,104|106,108|116,123|131,131|135,145|154,155|157,159|162,163|167,169|177,181|183,184|186,186|188,199|209,216|218,219|222,223|228,245|248,252 HHHHHHHHHHHHHHHHS?TT?EEEE------E?TTS?EEEEEE?S---------SS?EEEEEEEEESS?HH-HHHHHHTTTGGG-TTTS?TT?S----EEEEEEE?SSS-------EEEEEEEE???????S??-EEEEEEEEEEE-------?SS?EEE??EE???TTS??----?TTSEE?EE?S?EEEEEEETTEEE---------EEEEEEEE?EE??SS??--HHHHHHHHHHHHHHHHHH--HHHHT?????? 2E3Q|A PF01853.13_MOZ_SAS_seed 15 220 !Q:0,0|3,3|25,41|56,56|58,59|64,65|81,89|102,102|105,105|110,110|114,114|139,140|144,144|147,148|167,180|190,190|192,192|205,208|210,210|216,219 Q:1,2|4,24|42,55|57,57|60,63|66,80|90,101|103,104|106,109|111,113|115,138|141,143|145,146|149,166|181,189|191,191|193,204|209,209|211,215 ?SS?SSEEEEEETTEEEEEEETTTS-----------------HHHHHHHHHHHHTT?S??TTTT??TTEEEEEEEEEETTE---------EEEEEEEEEESS?TT?EEES?EEE?GGGTTSSHHHHHHHHHHHHHHHTT??BEE?SS??HHHHHHHHHHHHHHHHHH??????????????BHHHHHHHH?B?HHHHHHHHHHTT-???B?SSSBB???? 2OZU|A PF01855.14_POR_N_seed 32 258 !Q:6,7|13,15|21,22|35,37|41,46|51,51|69,70|76,76|95,97|105,107|112,113|116,116|125,130|134,134|139,140|159,160|162,164|177,177|185,185|188,188|195,195|206,214|216,217|219,219|222,223|227,227|229,230 Q:0,5|8,12|16,20|23,34|38,40|47,50|52,68|71,75|77,94|98,104|108,111|114,115|117,124|131,133|135,138|141,158|161,161|165,176|178,184|186,187|189,194|196,205|215,215|218,218|220,221|224,226|228,228|231,257 HHHHHH?-SEEEE???TTTHH--HHHHHHHHHHHT???TTS?---??EEEE?SSHHHHHHHHHHHHHTT??EEEEE?HHHHHHHHHHHHHHHHTT???EEEEEEB???SSSB??SB?SHHHHHTT------TSS?EEEE??SHHHHHHHHHHHHHHHHH--H???EEEEEETTTTTT?EEEEEEE?HH-HHHHHS?HHHHHHHHHH---------S??T-TS??EES?B??TTTHHHHHHTTHHHHHHHHHHHHHHHH 2C3M|A PF01857.15_RB_B_seed 6 178 !Q:0,0|25,25|27,36|38,38|64,64|82,86|100,101|110,110|113,157|159,159|162,162 Q:1,24|26,26|37,37|39,63|65,81|87,99|102,109|111,112|158,158|160,161|163,177 ?HHHHHHHHHHHHHHHHHHHHHHHH?S----------S?TTHHHHHHHHHHHHHHHSGGGSTTS?HHHHHHHHHHHHHHHTT-????HHHHHHHHTTSTT??THHHHSEE?SS---------------------------------------------S?EE?HHHHHHHTHHHHHHH 1GUX|B PF01858.12_RB_A_seed 7 218 !Q:0,7|20,20|23,24|37,38|62,62|65,74|76,76|101,109|116,116|119,122|140,155|164,165|180,183|186,187|211,211 Q:8,19|21,22|25,36|39,61|63,64|75,75|77,100|110,115|117,118|123,139|156,163|166,179|184,185|188,210|212,217 ????????HHHHHHHHHHHS?SS??HHHHHHHHTSSS??HHHHHHHHHHHHHHHHHHHHHHH?TT----------T?HHHHHHHHHHHHHHHHHHHHHHHT?????????HHHHHH?HH----HHHHHHHHHHHHHHHHT????????????????THHHHHTT??HHHHHHHHHHHHHH---?TT??HHHHHHHHHHHHHHHHTGGGSTT?HHHHHH 1GUX|A PF01861.11_DUF43_seed 6 257 !Q:12,16|21,23|25,25|41,41|45,45|52,53|56,56|66,67|74,74|76,76|92,94|99,101|105,107|113,113|120,122|140,140|144,144|151,151|155,156|172,173|186,188|190,190|203,212|215,217|226,227|229,232|234,238|242,243|245,245|247,247|249,256 Q:0,11|17,20|24,24|26,40|42,44|46,51|54,55|57,65|68,73|75,75|77,91|95,98|102,104|108,112|114,119|123,139|141,143|145,150|152,154|157,171|174,185|189,189|191,202|213,214|218,225|228,228|233,233|239,241|244,244|246,246|248,248 HHHHHHHHHHTT?????GGGT???B?HHHHHHHHHHHHHTT?STT?EEEEES-?TT?HHHHHHHHT??SEEEEE?S?HHHHHHHHHHHHHHT???EEEE???TTS???TTTSS?BSEEEE???SSHHHHHHHHHHHHHTB?STT?EEEEEE?TTT??HHHHHHHHHHHHHTS??EEEEEEEEEEEB???S?GGGSHHHHHSSS??------??SS???EEEEEEEE??T----T?-???SSS??S-S?S???????? 2QM3|A PF01862.11_PvlArgDC_seed 33 200 !Q:0,3|14,14|16,16|21,27|38,38|46,48|51,51|54,56|59,59|61,69|72,72|81,82|86,86|90,90|103,103|105,110|114,114|125,125|129,129|146,165|167,168|181,185|199,199 Q:4,13|15,15|17,20|28,37|39,45|49,50|52,53|57,58|60,60|70,71|73,80|83,85|87,89|91,102|104,104|111,113|115,124|126,128|130,145|166,166|169,180|186,198 ????EEEEEEEEEE?S-SHHH-------HHHHHHHHHT?TTSEEEE???EE?TT?--EE?S??----???TT?EEEEEEEE--EEE?STT?EEEEEEEEEEES-S------TTS?EEEEEEEESS?HHH-HHHHHHHHHHHHHHHH--------------------T??EEEEEEEEEEEE?----SSSEEEEEEEEEE? 2QQD|A PF01865.11_PhoU_div_seed 9 224 !Q:0,7|37,37|69,70|72,72|75,75|105,110|145,146|182,183|189,189 Q:8,36|38,68|71,71|73,74|76,104|111,144|147,181|184,188|190,223 ????????TTHHHHHHHHHHHHHHHTHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHGGG??S?SS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHT--????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS??SSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--HGGGS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 3L39|A PF01866.12_Diphthamide_syn_seed 57 368 !Q:0,1|16,17|20,23|26,26|28,31|36,36|38,41|45,46|51,51|56,56|64,67|69,77|80,80|86,95|97,97|111,114|122,122|139,145|148,148|152,156|159,160|166,166|171,171|175,175|177,183|185,185|204,204|206,209|211,211|218,218|221,224|226,227|231,236|252,253|255,258|266,266|271,272|286,287|290,290|300,301|309,314|320,320|322,322|329,330|332,333|336,336|338,338|340,340|351,360|362,367 Q:2,15|18,19|24,25|27,27|32,35|37,37|42,44|47,50|52,55|57,63|68,68|78,79|81,85|96,96|98,110|115,121|123,138|146,147|149,151|157,158|161,165|167,170|172,174|176,176|184,184|186,203|205,205|210,210|212,217|219,220|225,225|228,230|237,251|254,254|259,265|267,270|273,285|288,289|291,299|302,308|315,319|321,321|323,328|331,331|334,335|337,337|339,339|341,350|361,361 ??GGGHHHHHHHHHHH--HT----TT?E----EEEE?S????TTS??HHHH-HHTT?SEEEEEE????S?------??SS?EEEEE???---????H-HHHHHTHHHHHTT?---SEEEEEE?GGGGGGHHHHHHHHHH-------TT?EEE?????TT?-SSTTB?BTTB?GGG?S-------S?SEEEEESSSSHHHHHHHH-H----H?SEEEEE?TT----T??EEE?---??HHHHHHHHHHHHHHT--T?--?EEEEEEE?STTT??HHHHHHHHHHHHH--TT?EEEEEEESS??HHHHTTS-?---?SEEEE?S?THHHHS??S??SS?E-E?HHHHHHHTTS??--------S?????? 3LZD|A PF01867.11_Cas_Cas1_seed 140 471 !Q:4,4|6,6|9,9|13,13|21,41|44,59|63,69|72,72|76,77|83,83|85,86|102,103|108,108|111,118|126,137|139,141|147,147|179,183|188,203|214,214|216,242|263,267|269,315|317,348|375,376|379,380|384,390|394,395|418,420|424,424|426,427|433,434|437,451|453,453|456,456 Q:0,3|5,5|7,8|10,12|14,20|42,43|60,62|70,71|73,75|78,82|84,84|87,101|104,107|109,110|119,125|138,138|142,146|148,178|184,187|204,213|215,215|243,262|268,268|316,316|349,374|377,378|381,383|391,393|396,417|421,423|425,425|428,432|435,436|452,452|454,455|457,470 EEEE?S?EE-EEE?SSEEEEE?--------------------SS?---------------EEE-------EE?TTE--EEEEE?S?-EEEEHHHHHHHHHTT??EEEE?TT-----?-?EEEEEEE----------??S???HHHHH-HHHHHHHSHHHHHHHHHHHHHHHHHHHHHHH-----HTTT??------------??SSHHHHHHHH-H------?------------------?-SHHHHHHHHHHHHHHHHHHT?-???S-----------------------------------------------S?---?????----??------????---?--?SHHHHHHHHHHHHHHHHHHHHHHTSS??TT??SSS-?---??SSS??HHHHHHHHHHHHHTHHHHHHHH---TTT?S?-GGGEE??SS---------------S?EE?HHHHHHHHHHHHHH 3GOD|A PF01868.11_UPF0086_seed 36 122 !Q:0,15|18,18|25,25|33,33|37,38|53,53|60,60|63,63|75,101|105,105|109,113|117,121 Q:16,17|19,24|26,32|34,36|39,52|54,59|61,62|64,74|102,104|106,108|114,116 ?????????----???SS?EEEEEE?SSTTTTT?EEE??EEETTEEEEEETTT-EEEEEE?TT?EEEEEETTTEE---------------------------EEE?SSS????-STT????? 1PC0|A PF01869.15_BcrAD_BadFG_seed 19 489 !Q:8,9|15,23|27,28|35,105|110,110|131,132|135,230|232,232|235,237|244,245|247,248|251,251|263,263|269,269|284,284|287,289|305,305|309,309|314,317|321,322|346,347|350,353|366,366|380,383|402,402|428,428|437,437|450,453|457,464|468,483 Q:0,7|10,14|24,26|29,34|106,109|111,130|133,134|231,231|233,234|238,243|246,246|249,250|252,262|264,268|270,283|285,286|290,304|306,308|310,313|318,320|323,345|348,349|354,365|367,379|384,401|403,427|429,436|438,449|454,456|465,467|484,488 EEEEESSS??EEEEE?--------TTS?-EEEEEE???------------------------------------------------------------------??TTTS?HHHHHHHHHHHHHHHHHHTT??SS------------------------------------------------------------------------------------------------S?BS---EEEEEE??S??SS?HHHHHHHHHHH?TTSBS?EEEEEHHHHHHHHH?SS?--EEEEEESSSEEEEEE?SSS?EEEE????TTT??TTSHHHHHHHHHHHHHHHHHTSS??SS--??HHHHHHHHHHHT?SSHHHHHHHHHTS--??HHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHGGGS?GGGTSSSS?EEEEEESGGGGG----HHH--------HHH----------------HHHHH 4EIA|A PF01870.13_Hjc_seed 16 136 !Q:14,38|46,46|49,51|54,56|62,62|65,66|75,75|79,81|85,92|108,110|112,112|120,123|127,128 Q:0,13|39,45|47,48|52,53|57,61|63,64|67,74|76,78|82,84|93,107|111,111|113,119|124,126|129,135 HHHHHHHHHHHHTT------------------------?EEEEBTT?SS?--SS???SEEEE?SS?-EEEEEEEE?SSS--?EEE--------EHHHHHHHHHHHHHH---T?EEEEEEE?---TTS??EEEEGGG 2WJ0|A PF01871.12_AMMECR1_seed 76 235 !Q:16,29|32,33|39,39|41,41|48,48|54,59|63,65|77,86|103,104|108,113|116,116|121,122|131,133|136,137|139,141|147,147|150,153|157,157|164,169|171,171|178,178|187,188|199,199|204,207|213,213|222,222|226,227|230,233 Q:0,15|30,31|34,38|40,40|42,47|49,53|60,62|66,76|87,102|105,107|114,115|117,120|123,130|134,135|138,138|142,146|148,149|154,156|158,163|170,170|172,177|179,186|189,198|200,203|208,212|214,221|223,225|228,229|234,234 HHHHHHHHHHHHHHHS??--------????TT??GGGGS-B?EEEEEE-EETTS?-----GGG---TEEEEEEESSS-------?--SBHHHHHHHHHHHHHH??TTS?--???GG-GGGG--EEEEEEEE???EE??S?--GGGGG-GG??--TTT?EEEEEE------T-TEEEEE?THHHHHHT??HHHHHHHHHH-HTTS?---TTGGG?TTSEEEEE?EEE--EE----E 1ZQ7|A PF01872.12_RibD_C_seed 27 257 !Q:0,0|12,12|16,16|19,30|33,47|67,69|76,79|81,82|85,86|88,99|101,102|108,108|111,114|117,117|119,124|130,130|132,132|138,138|140,142|157,157|162,165|169,170|182,182|184,185|192,192|199,199|205,207|216,220|224,224|228,228|231,232|239,241 Q:1,11|13,15|17,18|31,32|48,66|70,75|80,80|83,84|87,87|100,100|103,107|109,110|115,116|118,118|125,129|131,131|133,137|139,139|143,156|158,161|166,168|171,181|183,183|186,191|193,198|200,204|208,215|221,223|225,227|229,230|233,238|242,256 ?EEEEEEEEETT?BSS?TT????-----???HH---------------HHHHHHHHHHTSSEEEEEH---HHHHHH????S??SS??S------------S??EEEEE?TT????TT?G------GGSTT-S?EEEEE?S???HHHHHHHHHHHHTT?EEEE??--SSS??HHHHHHHHHHT-T??EEEEEE?HHHHHH-HHHTT???EEEEEEES?????TTS?BSS?SS??SSGGGS-??EEEEEEEEETTEEEE 3ZPC|A PF01873.12_eIF-5_eIF-2B_seed 13 138 !Q:0,0|2,7|14,17|19,22|26,28|32,32|38,38|55,55|58,58|70,71|86,88|106,106|110,111|113,114|129,129|133,134 Q:1,1|8,13|18,18|23,25|29,31|33,37|39,54|56,57|59,69|72,85|89,105|107,109|112,112|115,128|130,132|135,137 ?E------EESSTT???-S????EEE???EEE?SSSSS?EEEETTHHHHHHHTTS?TH-HHHHHHHHHHT??EEEETTTTEEEEEB???HHHHHHHHHHHHHHTTS?TTT??S??EEEEETTTTEEEEE?SSS??EEE 1NEE|A PF01874.11_CitG_seed 135 369 !Q:0,38|45,45|61,77|92,99|116,116|123,142|152,153|168,188|197,197|200,201|205,206|215,215|218,218|242,263|281,283|291,291|296,296|306,313|315,333|346,347|351,353 Q:39,44|46,60|78,91|100,115|117,122|143,151|154,167|189,196|198,199|202,204|207,214|216,217|219,241|264,280|284,290|292,295|297,305|314,314|334,345|348,350|354,368 ??--------------------------??????--???HHHHHH-HHHTTHHHHHHHHHH??---------------HHHHHHHHHHHTTS????????HHHHHHHHHHHTTTTS?SHHHHH--------------------HHHHHHHHT??HHHHHHHHHHHHHH?????-----??????----?HHHHHHHH-HH--HHT??HHHHHHTS?TT?HHHHHHHTTSHHHHHHHHHHHHH---------------------?SSHHHHHHHHHHHHTTS-??HHHHHHH?HHHH-HHHHHHHHH?------?S-------------------HHHHHHHHHHHH--HHT???HHHHHHHHHHHHHHH 3H9P|A PF01875.12_Memo_seed 11 347 !Q:0,1|9,9|11,11|21,21|28,30|32,32|34,38|44,52|54,54|69,70|72,75|78,79|87,87|91,93|99,99|105,106|109,110|114,114|125,125|127,133|137,138|145,146|164,166|169,169|177,177|179,180|200,202|209,212|221,240|243,252|275,279|291,295|314,314|317,318|331,333|337,338|347,347 Q:2,8|10,10|12,20|22,27|31,31|33,33|39,43|53,53|55,68|71,71|76,77|80,86|88,90|94,98|100,104|107,108|111,113|115,124|126,126|134,136|139,144|147,163|167,168|170,176|178,178|181,199|203,208|213,220|241,242|253,274|280,290|296,313|315,316|319,330|334,336|339,346 ??TTBTTTB?S?HHHHHHHHH-HHHHTS???S?S?----SEEEE-------??S?HHHHHHHHHHHHTT??T----TT??EEEEEEE?SSS??-SSEEE?SSSEE??SS??EEB?HHHHHHHHHT-T?------EEE??HHHHHH??TTGGGHHHHHHHHGGGT---TS?EEEEEEE?S??HHHHHHHHHHHHHHHTSTT---EEEEEE????EEBGGGTB???----------------?GG----------GSSHHHHHHHHHHHHHHHHHTT----?HHHHHHHHHHH???-?TTHHHHHHHHHHHHHHHT-TT??EEEEEEEEEESS???STT??EEEEEEEE- 3BD0|A PF01876.11_RNase_P_p30_seed 62 207 !Q:10,11|14,14|16,19|30,35|42,42|44,44|56,65|70,70|75,77|81,81|83,84|96,97|108,125|127,130|142,143|155,156|161,163|169,171|181,181|184,186|188,194|204,204 Q:0,9|12,13|15,15|20,29|36,41|43,43|45,55|66,69|71,74|78,80|82,82|85,95|98,107|126,126|131,141|144,154|157,160|164,168|172,180|182,183|187,187|195,203|205,206 HSSEEEEEES??HH-H----HHHHHHHTTT------SEEEEE?S?HHHHHHHHHTT---------?SEEE?TTTT---SSS?S??HHHHHHHHHHT?-EEEEESHHHH------------------H??--HHHHHHHHHHH--HHHHHHHHHTT??EEEE???SSGGG???HHHHHHHHH-HT---T-----??HHHHHHTTT-HH 2CZV|A PF01877.12_RNA_binding_seed 52 142 !Q:9,9|13,13|25,35|38,41|45,54|62,62|83,85|91,91|98,99|102,102|109,109|115,115|118,120|122,124|127,131|133,133 Q:0,8|10,12|14,24|36,37|42,44|55,61|63,82|86,90|92,97|100,101|103,108|110,114|116,117|121,121|125,126|132,132|134,141 EEEEEEEEE?TTS?HHHHHHHHGGG?----------SS????EEE??????????EEEEEEE?SHHHHHHHHHHHHHHHGGGH---HHHHH-HHHHHB?-TT?EEEEEE?HHHHH-TT???B??-SS-----S?EEEEEEEE 2WNY|A PF01878.13_EVE_seed 140 231 !Q:0,0|2,4|9,14|19,20|27,27|29,30|36,36|43,44|47,52|58,59|63,63|65,66|69,69|76,82|86,88|97,97|99,100|106,106|111,111|117,118|121,128|132,132|134,134|143,143|156,160|165,165|173,173|175,186|190,191|196,196|198,199|201,213|219,219|228,228 Q:1,1|5,8|15,18|21,26|28,28|31,35|37,42|45,46|53,57|60,62|64,64|67,68|70,75|83,85|89,96|98,98|101,105|107,110|112,116|119,120|129,131|133,133|135,142|144,155|161,164|166,172|174,174|187,189|192,195|197,197|200,200|214,218|220,227|229,230 ?E---EEEE------EBSS??BSSSSB?B??SHHHH-TSGGGE--EE??????HHHHH--HHH-H??TT?EEEEEE??-----SSS--?EEEEEEEE-E--EEEEE?GGGT?TTSTT??TT??------TTS?S?EEEEEEEE-EEEEEEEEHHHH-----HHHH-HHHHHHT?T------------TSS?-HHHH?T--T------------?SEEEE?HHHHHHHH-HG 1WMM|A PF01880.13_Desulfoferrodox_seed 58 153 !Q:0,2|6,6|8,12|14,14|19,20|24,24|27,27|38,38|41,44|49,49|62,62|64,65|67,67|74,76|79,80|83,83|86,86|89,89|91,94|103,103|106,133|139,139 Q:3,5|7,7|13,13|15,18|21,23|25,26|28,37|39,40|45,48|50,61|63,63|66,66|68,73|77,78|81,82|84,85|87,88|90,90|95,102|104,105|134,138|140,152 ???TTT?T-----T?EEEE??SEE?TT?EEEEEEEESS-SS????SSSS?EEEEEEEEEETT?S??E-EEEEEE???BS??TT?TT?SS?B??--SEEEEEEE?SS?---------------------------EEEEE-EEEETTTEEEEEE 2HVB|A PF01881.11_Cas_Cas6_seed 46 202 !Q:5,8|11,11|17,19|21,24|33,34|37,44|53,54|56,56|66,71|81,81|87,91|108,112|116,117|119,123|131,133|137,141|148,154|158,159|167,167|173,174|185,185|189,189|193,193|195,197|201,201 Q:0,4|9,10|12,16|20,20|25,32|35,36|45,52|55,55|57,65|72,80|82,86|92,107|113,115|118,118|124,130|134,136|142,147|155,157|160,166|168,172|175,184|186,188|190,192|194,194|198,200 HHHHH----HS?EEEET---T----EEEEEEEE--EE??????-?SEEEEEES--S?BBEEEEEEE------TTEEEEEEE?TTSTT-----HHHHHHHHHHHHHHHH-----HSS??S--???EEEEEEE---EEE-----EEEEET-------TEE--EEEEEEE-EEEEE?-HHHHHHHHHH?SBS?GGG-T???EEE? 3UFC|X PF01883.14_DUF59_seed 74 89 !Q:10,10|12,12|17,17|25,32|36,36|38,42|44,45|52,53|57,58|60,61|76,76|81,84 Q:0,9|11,11|13,16|18,24|33,35|37,37|43,43|46,51|54,56|59,59|62,75|77,80|85,88 HHHHHHHHTT?B?TTTS-SBTTTTT????----EEE?T-----T-?EEEEEE??SSS??S--SHHHHHHHHHHHHH-TSSS--??EEEE 3CQ1|A PF01884.12_PcrB_seed 5 251 !Q:0,1|5,9|15,15|19,21|29,31|36,36|42,44|46,48|50,51|66,68|72,73|76,82|135,136|141,142|150,155|171,172|179,180|184,186|188,188|198,198|208,210|222,222|229,229|236,242|250,250 Q:2,4|10,14|16,18|22,28|32,35|37,41|45,45|49,49|52,65|69,71|74,75|83,134|137,140|143,149|156,170|173,178|181,183|187,187|189,197|199,207|211,221|223,228|230,235|243,249 ??GGG??---EEEEE?TTS???HHHHHHH---HTTT?SEEEE???T---T??HHHHHHHHHHHTTS???EEE??SS???????SSEEEEEEETTBSBGGGTTHHHHHHHHTTGGGHHHHHHHHHSTTEEEEEEEE??TTSH--HHHHTTB?-????HHHHHHHHHHHHHTT??SEEEEE?-TTS???H-HHHHHHHHH?SSSEEEEES???SHHHHHHHHHH-SSEEEE?HHHHHH?------HHHHHTT? 1VH7|A PF01885.11_PTS_2-RNA_seed 88 412 !Q:0,10|22,23|29,32|35,36|38,39|51,56|58,58|60,60|63,70|81,81|84,85|90,220|229,233|236,252|255,280|286,287|299,301|303,305|315,344|353,355|374,374|378,392|395,395|404,410 Q:11,21|24,28|33,34|37,37|40,50|57,57|59,59|61,62|71,80|82,83|86,89|221,228|234,235|253,254|281,285|288,298|302,302|306,314|345,352|356,373|375,377|393,394|396,403|411,411 ??-------??HHHHHHHHHHT?-TGGGT????TT??E--EHHHHHHHHHH------T-T?TT-?-----?HHHHHHHHHH?SS??EEEE-----------------------------------------------------------------------------------------------------------------------------------TTEEEESS---??SS?-??------???---?SS?-----------------------??SEEEE??BGGGHHHHHHH?--B???SSSSEEEES?-----------------------------HHHHHHHH---TTSSSSBEEEEEEHHHHH-HTT------------???EE?SSSEEEES------?B 1WFX|A PF01887.11_SAM_adeno_trans_seed 121 477 !Q:0,0|8,8|25,30|33,34|41,41|43,43|46,46|62,62|65,65|71,72|79,80|85,88|92,92|95,96|109,112|115,116|118,134|136,141|143,143|145,158|164,166|170,171|174,184|186,197|200,201|204,204|215,215|219,220|224,226|231,232|234,248|250,261|264,264|266,270|272,277|284,284|288,288|290,290|292,293|305,309|312,314|317,321|328,337|342,385|391,391|396,426|429,429|432,432|435,435|439,439|451,456|458,458|465,466|469,471|473,473 Q:1,7|9,24|31,32|35,40|42,42|44,45|47,61|63,64|66,70|73,78|81,84|89,91|93,94|97,108|113,114|117,117|135,135|142,142|144,144|159,163|167,169|172,173|185,185|198,199|202,203|205,214|216,218|221,223|227,230|233,233|249,249|262,263|265,265|271,271|278,283|285,287|289,289|291,291|294,304|310,311|315,316|322,327|338,341|386,390|392,395|427,428|430,431|433,434|436,438|440,450|457,457|459,464|467,468|472,472|474,476 ?EEEEESS?SSSSHHHHHHHHHHHH----?-TT??EEEEES?S?TT?HHHHHHHHHHHHTTS?TT?EEEEE??TTTTSS??EEEE----EET-TS-?EEEEESSSTTHH----HH--H-----------------H------H?E--------------EEEEE???GGG--SS-----------S------------SS??SS?HHHHTHHHHH-HHH--HTT-??GGGG??B?--------------S??????????--EE?S-----S------EEEEEE-EEE?T-T??EEEEEEHHHHT-----TS???TT?----EEEEEE----------TTEE--------------------------------------------EEEEE?SSGG-------------------------------GS?TT?EE-EEE?TTSEEEEEETT------B?HHHHHT??TT--?E-EEE 2ZBU|A PF01888.12_CbiD_seed 6 268 !Q:5,5|8,8|26,27|29,29|36,37|40,40|42,43|50,55|65,67|70,70|72,73|78,78|88,88|90,94|98,98|102,110|117,117|119,119|139,140|143,144|149,149|160,160|166,166|171,171|173,174|180,182|194,199|203,203|222,222|226,227|232,237|240,240|247,247|253,253|257,257|260,260 Q:0,4|6,7|9,25|28,28|30,35|38,39|41,41|44,49|56,64|68,69|71,71|74,77|79,87|89,89|95,97|99,101|111,116|118,118|120,138|141,142|145,148|150,159|161,165|167,170|172,172|175,179|183,193|200,202|204,221|223,225|228,231|238,239|241,246|248,252|254,256|258,259|261,267 TEEEE?EE?HHHHHHHHHHHHHHGGG--S?EEEEEE??TT-S??EEEEEE------EETTEEEEE???TT?S??TTTT?EEEEEEESS?E-----EEE?TEE?--------EETTEE?B?HHHHHHHHHHHHHHHHHTT??SE--EEEE?TTHHHHHHTT?GGGGT?BSEE?B??SSSEE???SHHHHHHHHHH------GGG?SEEEEESSHHHHHHHHHH?TTS--EEEE-----?TT?HHHHTT?SSEEE-EEE?HH-HHHHHHS 1SR8|A PF01890.11_CbiG_C_seed 204 178 !Q:0,0|8,8|11,14|29,35|38,39|43,44|50,50|54,55|57,59|70,71|73,73|78,78|84,85|91,91|94,96|104,104|106,106|108,110|115,115|124,130|135,135|138,146|151,151|154,154|157,170 Q:1,7|9,10|15,28|36,37|40,42|45,49|51,53|56,56|60,69|72,72|74,77|79,83|86,90|92,93|97,103|105,105|107,107|111,114|116,123|131,134|136,137|147,150|152,153|155,156|171,177 ?EEEEEEE?TT?--?HHHHHHHHHHHHHH-------TT??GGG??EEEEE?SSS??H---HHHHHHHHHT--S?EEEE?HHHHH--TTGGG?SS?-?HHHHHHH-S?S--?HHHH-HHHHHHHH-------HHSS?EE---------ESSS?EE?SS--------------EEEEEEE 2W6K|A PF01893.11_UPF0058_seed 23 100 !Q:0,5|25,25|27,30|34,35|47,48|51,51|55,55|76,76|97,99 Q:6,24|26,26|31,33|36,46|49,50|52,54|56,75|77,96 ??----HHHHHHHHHHHHHHHHHHH-T----STT??TTTTHHHHHHT??TT?TTS?HHHHHHHHHHHHHHHHHHHH-HHHHTTHHHHHHHHHHHHHH??? 2GF4|A PF01894.12_UPF0047_seed 109 180 !Q:2,2|7,9|17,18|20,20|29,32|42,49|51,51|67,73|77,90|92,92|94,94|97,118|120,120|131,132|145,147|159,167|169,170 Q:0,1|3,6|10,16|19,19|21,28|33,41|50,50|52,66|74,76|91,91|93,93|95,96|119,119|121,130|133,144|148,158|168,168|171,179 EE?HHHH---HHHHHHH--T?SEEEEEEE??-?SSEEEEEEE-------?S?THHHHHHHHHHHHHS?------SSS--------------S?S?TT----------------------S?HHHHHHHHHH-?SEEEEEEETTEE???TTEEEEEEESS?--------S?-EEEEEEEEE 1VMJ|A PF01895.14_PhoU_seed 388 164 !Q:9,9|19,19|21,23|27,30|32,33|37,37|41,41|43,44|47,50|58,65|70,78|81,85|92,92|95,96|98,102|105,110|112,123|127,129|131,132|135,138|142,143|154,154 Q:0,8|10,18|20,20|24,26|31,31|34,36|38,40|42,42|45,46|51,57|66,69|79,80|86,91|93,94|97,97|103,104|111,111|124,126|130,130|133,134|139,141|144,153|155,163 HHHHHHHHH-HHHHHHHHH-H---HTT-?--H--HHH-HHH-H--HT----HHHHHHH--------HHHH---------HH-----HHHHHH-HH--H?--??HH------H------------HHH---H--HH----HHH--HHHHHHHHHH-HHHHHHHHH 2I0M|A PF01896.14_DNA_primase_S_seed 73 344 !Q:11,11|14,23|26,28|51,69|75,75|77,85|94,100|106,107|119,124|127,127|129,152|155,156|179,179|195,195|209,210|215,233|248,257|269,272|278,278|281,288|291,291|294,294|296,303|307,307|310,311|313,342 Q:0,10|12,13|24,25|29,50|70,74|76,76|86,93|101,105|108,118|125,126|128,128|153,154|157,178|180,194|196,208|211,214|234,247|258,268|273,277|279,280|289,290|292,293|295,295|304,306|308,309|312,312|343,343 EEEEGGGGTTT?SS--------??TT???HHHHHHHHHHHHHHHHHHHHTS?-???--------------EEEEE?S---------SSEEEEEE-----??HHHHT??HHHHHHHHHHH??????SS?S??????------------------SS??HHHHHHHHHHHHHHHHHHTTTS?TTSSHHHHHHHHTTS?GGGHHHHHHHHHH??SHHH-------------------HHHHHHHHHHHHHH??????????HHHHHHHHHHS????HHHHH?TT?------?EE?TT?B-------?TTT?BB??B----------------------------??G 1G71|A PF01900.14_RNase_P_Rpp14_seed 65 190 !Q:10,44|46,48|50,70|72,72|95,100|104,105|114,118|138,139|144,162|175,177 Q:0,9|45,45|49,49|71,71|73,94|101,103|106,113|119,137|140,143|163,174|178,189 EEEEEEEEES-----------------------------------S???H---------------------H-HHHHHHHHHHHHHHHHHHHHHH----??EEE--EEETTTTE-----EEEEEEGGGHHHHHHHHHT??EETT-------------------EEEEEEEEEEES---SHHHHHHHTTTT 2AV5|A PF01902.12_ATP_bind_4_seed 6 224 !Q:0,0|6,7|24,24|34,48|60,61|67,70|86,90|95,97|100,100|116,116|120,120|125,126|139,139|147,147|151,152|158,158|160,161|176,178|181,181|193,193|196,196|210,210|213,213 Q:1,5|8,23|25,33|49,59|62,66|71,85|91,94|98,99|101,115|117,119|121,124|127,138|140,146|148,150|153,157|159,159|162,175|179,180|182,192|194,195|197,209|211,212|214,223 ?EEEEE??SSHHHHHHHHHHHHTT?EEEEEEEEE?????-?????????TTHHHHHHHHT??EEEEE????TTSHHHHHHHHHHTB?---?SEEE???SS?HHHHHHHHHHHHHHT?EEE?TTTT??HHHHHHHHHHTT?EEEEEEE?STT??GGGTT?B??HHHHHHHHHHHHHH???TT?GGGTEEEEEEE?TT?SEEEEEEEEEEEE?SS?EEEEEEEEEE 3RJZ|A PF01903.12_CbiX_seed 76 176 !Q:0,3|5,6|18,18|27,29|31,32|42,42|50,53|55,55|61,65|67,68|71,77|82,83|85,89|97,102|105,110|114,118|126,151|153,154|156,157|160,162 Q:4,4|7,17|19,26|30,30|33,41|43,49|54,54|56,60|66,66|69,70|78,81|84,84|90,96|103,104|111,113|119,125|152,152|155,155|158,159|163,175 ???-S?-HHHHHHHHHHH-HHHHHHST---T?-EEEESSSSS-SBHHHHH----H-HHHHT-----T??EE-------EEEE??S-???-HHHHHHH------HH------HHH-----HHHHHHT-------------------------?E--E--EE???GGGSHHHHHHHHH 1TJN|A PF01904.13_DUF72_seed 218 451 !Q:2,2|5,6|8,8|11,11|15,16|23,25|30,32|36,36|39,39|42,49|55,55|59,62|64,66|68,68|70,71|77,78|83,83|85,87|89,89|95,126|132,132|136,140|143,143|149,151|156,159|167,168|170,171|173,178|192,232|234,234|239,240|244,244|246,254|256,256|260,260|266,266|268,271|274,274|281,287|291,313|315,325|333,334|336,339|344,351|353,354|360,364|366,371|375,377|386,386|388,389|393,394|397,418|421,421|427,430|433,433|435,437 Q:0,1|3,4|7,7|9,10|12,14|17,22|26,29|33,35|37,38|40,41|50,54|56,58|63,63|67,67|69,69|72,76|79,82|84,84|88,88|90,94|127,131|133,135|141,142|144,148|152,155|160,166|169,169|172,172|179,191|233,233|235,238|241,243|245,245|255,255|257,259|261,265|267,267|272,273|275,280|288,290|314,314|326,332|335,335|340,343|352,352|355,359|365,365|372,374|378,385|387,387|390,392|395,396|419,420|422,426|431,432|434,434|438,450 TB?TT??G-GG-HHH--HHHHTS???EEEE???SSS-SS?HH--------HHHHH-HTT----S?--T-T-?EEEEE??HHHH-H---T-HHHHT?------------------------------?SHHHH-HHH-----HH-HHHHH---HHTT?---EEEEEEE??T--T--????HHHHHHHHHHHHH??---------------------------------------S?EEEE??BGG-G?--------S-HHH-HHHHH-H----HT?EEEEEE???---?TTB????----------------???S-----------SSEEEEE--E????TTTT--------T??GGGTT?????H------HHH---HHHHHHHH-H--HHT--TS----------------------SE-EEEEE??-?GG-G---HHHHHHHHHHHHH 1VPQ|A PF01905.11_DevR_seed 28 397 !Q:12,24|31,31|37,41|52,52|72,74|76,79|85,88|90,90|93,93|95,95|105,110|127,127|134,134|138,151|155,167|171,172|178,178|182,184|187,187|191,193|201,232|234,234|246,246|252,254|256,316|319,320|327,327|332,332|348,362|375,375|377,384|388,388|397,397 Q:0,11|25,30|32,36|42,51|53,71|75,75|80,84|89,89|91,92|94,94|96,104|111,126|128,133|135,137|152,154|168,170|173,177|179,181|185,186|188,190|194,200|233,233|235,245|247,251|255,255|317,318|321,326|328,331|333,347|363,374|376,376|385,387|389,396 EEEEEEEEHHHH???????-?????EEEEEE-EEETT-----EEEEEEEEEB?HHHHHHHHHHHHHHHHHHH---T????TTGGG----T?TT?S?SHHHHHHHT???--?SSGGGHHHHHHHHHHH?HHHHHS?EEE-----------?--SSS------------?EEE??SEEEB?BEE???SS?HHH---HHHHHSS?????---------------????????????S?SEEEEEEEEEE?GGGTT???S?------------------------------------------------------------SS??THHHHH-HHHH-HHHHHHHHHTHHHHH???-???????????EEEEEEEEEEES-S??????--SSS-TTHHHHHH- 3PS0|A PF01906.12_YbjQ_1_seed 171 122 !Q:0,0|3,3|8,9|24,25|30,30|32,34|44,45|50,52|56,56|60,60|83,83|97,102|107,107|110,110 Q:1,2|4,7|10,23|26,29|31,31|35,43|46,49|53,55|57,59|61,82|84,96|103,106|108,109|111,121 ?EE?SSSS?-TTEEEEEEEEEEEE--EEEE?H---HHHHHHTTT??SEEE---TTT?THH-HHHHHHHHHHHHHHHHHHHHHT?SEEEEEEEEEEEE------STTS?EE-EEEEEEEEEEE 3QKB|A PF01907.14_Ribosomal_L37e_seed 46 57 !Q:0,0|9,10|12,13|17,18|22,22|25,25|37,37|43,47|49,49|51,51 Q:1,8|11,11|14,16|19,21|23,24|26,36|38,42|48,48|50,50|52,56 ?TTTHHHHT??S?-SEE??TTT?SS?EETTTTEETTT?TTSSS??-??S-S?HHHHH 1S1I|Y PF01909.18_NTP_transf_2_seed 117 157 !Q:11,11|13,17|19,20|30,34|36,38|41,45|47,47|53,53|56,57|66,68|74,74|80,83|86,86|89,89|97,97|115,128|131,131|135,139|153,153 Q:0,10|12,12|18,18|21,29|35,35|39,40|46,46|48,52|54,55|58,65|69,73|75,79|84,85|87,88|90,96|98,114|129,130|132,134|140,152|154,156 HHHHHHHHHTT?T-----T??EEEESTTTT-----T???TT-----S?EEEEE?SS??GGGHHHHH---HHHHH-HHHHT----TS?SS?EEEESSS?EEEEEEETTTTEEEEEE--------------SS?SST-----THHHHHHHHHHHS?TTH 1Q79|A PF01910.12_DUF77_seed 104 109 !Q:9,11|13,16|19,20|32,35|40,41|76,76|91,91|93,96|98,100 Q:0,8|12,12|17,18|21,31|36,39|42,75|77,90|92,92|97,97|101,108 EEEEEEESS--?S----SS??HHHHHHHHHHH----TTSS-?EEEEETTEEEEEESSHHHHHHHHHHHHHHHHHTT?SEEEEEEEEEEESS-S?-??H---HHHHHHHH 2EKY|A PF01912.13_eIF-6_seed 65 218 !Q:3,3|8,10|18,18|21,21|25,25|29,30|44,45|48,48|50,50|54,54|60,60|65,65|68,68|78,79|85,88|95,95|104,107|110,110|113,113|119,119|126,126|129,130|144,144|149,150|156,156|164,164|167,167|171,171|174,175|188,190|192,193|197,198|205,205|213,213|216,216 Q:0,2|4,7|11,17|19,20|22,24|26,28|31,43|46,47|49,49|51,53|55,59|61,64|66,67|69,77|80,84|89,94|96,103|108,109|111,112|114,118|120,125|127,128|131,143|145,148|151,155|157,163|165,166|168,170|172,173|176,187|191,191|194,196|199,204|206,212|214,215|217,217 EEE?BTTB?-?HHHHEEE?SS?EEE-ETT??HHHHHHHHHHHTT--TS?E-EEE?BTTBS?HHHH?EE?SSEEEEETT??HHHHH----HHHHHS?TTSEEEEE??-?SS?HH-HHEEE?SSEEEE?TT??HHHHHHHHHHHTS-EEEE??BTTBS?GGGSEEE?SS?EEE?TT??HHHHHHHHHHHT---S?-EEE??BTTTBS?HHHHEEE?SS?E 1G62|A PF01913.13_FTR_seed 36 168 !Q:0,0|8,8|10,10|26,26|41,41|43,43|45,45|51,51|58,58|61,61|70,70|78,81|106,106|112,118|121,123|128,128|140,141|145,146|151,155|157,160 Q:1,7|9,9|11,25|27,40|42,42|44,44|46,50|52,57|59,60|62,69|71,77|82,105|107,111|119,120|124,127|129,139|142,144|147,150|156,156|161,167 ?EETTEEE?S?EEEEEEEEEEEEEEE?SSHHHHHHHHHHHH?S?S?TTTSS?EEEEEE-EE?TTTSTTSS?EEEEEEE----ESSHHHHHHHHHHHHHHHTTTSTT?EEEES?------TT--?SEEE?HHHHHHGGGTT??EEE--EETT-----E----EEEEEEE 2FHJ|A PF01915.17_Glyco_hydro_3_C_seed 107 592 !Q:0,0|6,6|8,12|14,15|17,18|22,36|46,87|89,89|91,91|94,98|100,105|108,134|146,147|151,156|159,160|166,166|169,169|173,175|189,189|193,194|197,199|206,206|212,212|215,217|225,227|236,237|241,243|272,273|275,275|284,285|293,293|296,297|306,306|310,319|328,330|346,349|358,361|370,411|415,419|430,430|434,438|447,447|450,454|459,473|475,476|481,493|508,513|515,520|523,523|525,525|529,537|544,569|572,572|574,574|576,576|582,582|584,584|588,589 Q:1,5|7,7|13,13|16,16|19,21|37,45|88,88|90,90|92,93|99,99|106,107|135,145|148,150|157,158|161,165|167,168|170,172|176,188|190,192|195,196|200,205|207,211|213,214|218,224|228,235|238,240|244,271|274,274|276,283|286,292|294,295|298,305|307,309|320,327|331,345|350,357|362,369|412,414|420,429|431,433|439,446|448,449|455,458|474,474|477,480|494,507|514,514|521,522|524,524|526,528|538,543|570,571|573,573|575,575|577,581|583,583|585,587|590,591 ?EEEEE?T-----T??S??SSS--------------?EEEESTTTS--------------------------------------????S?B-ST-----T?-?--?BS?-----------------------???HHHHHHHHHTS??EEE??????SS??BSGGG?BS?TTS???SSSBSEEEEEESS?TTT??TT???SEEEEE?SSEEE?TT???TTSBTTB???EEEEEEEE??SSS---EEEEEEEEEESEEEEEETTEEEEEESSS??B?STTTTTSB??EEEEEEE?TT??EEEEEEEE?TTT??????????EEEEEEEE???HHHHHHHHHHHHHTS----SEEEEEEE?--?TTTSBTTB----------------------------------------??SSS???--TTHHHHHHHH-HHH?----SSEEEEEE?SS????-TTGG---------------G??EEEE?????--------TTHHHHHHHHHHTS------S??????SS?B?SSG---------GGSTTT--------------------------TS?S?B-TTEEE?T-TTT??TH 1X38|A PF01916.12_DS_seed 7 342 !Q:11,11|16,16|35,37|46,46|49,50|52,54|63,63|83,84|90,90|104,106|109,110|113,114|156,159|162,178|188,191|195,199|202,202|212,213|216,216|236,243|258,258|268,268|293,295|299,300|304,305|316,316|319,321|327,327 Q:0,10|12,15|17,34|38,45|47,48|51,51|55,62|64,82|85,89|91,103|107,108|111,112|115,155|160,161|179,187|192,194|200,201|203,211|214,215|217,235|244,257|259,267|269,292|296,298|301,303|306,315|317,318|322,326|328,341 HHHHHHGGGGT?HHHH-HHHHHHHHHHHHHHHHTS???HHHHHHHT?SS??S???SSEEEEEE?THHHHSTHHHHHHHHHHTT??SEEEE?HHHHHHHHHTTTS?-?EE??SS??HHHHHHTTEEEETTEEEEHHHHHHHHHHHHHHHHHHHHHHH----TS???------------??HHHHHHHHH----HHH?---?TT?HHHHHHHTT??EE?TTTTSSHHHHHHHHHHHHS-??-????HHHHHHHHHHHHHT?SSEEEEEES?THHHHHHHHHHHTTTSBSEEEEEE???STT??STT??HHHHHHHTSB?TT???EEEES?HHHHHHHHHHHTGG 1RQD|A PF01918.16_Alba_seed 126 129 !Q:0,0|4,5|7,8|10,10|23,74|78,81|91,91|109,109|111,115|117,118|120,120 Q:1,3|6,6|9,9|11,22|75,77|82,90|92,108|110,110|116,116|119,119|121,128 ?EEE??S--S?HHHHHHHHHHHH----------------------------------------------------TTS---?SEEEEEEEG-GGHHHHHHHHHHHHHHT?T-----T-?E-EEEEEEEE 1NH9|A PF01920.15_Prefoldin_2_seed 56 111 !Q:41,41|44,48|61,62|105,105|109,110 Q:0,40|42,43|49,60|63,104|106,108 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS?TT---??EEEEETTEEEEE-?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HTS?? 3AEI|A PF01921.13_tRNA-synt_1f_seed 39 454 !Q:0,1|15,22|24,27|36,37|40,42|48,48|64,64|66,66|68,73|81,81|86,90|92,94|97,97|100,101|114,115|118,118|121,121|142,145|170,173|190,194|197,225|231,231|235,238|241,241|246,247|251,251|255,268|272,274|277,277|282,291|295,295|308,310|312,313|324,324|338,342|344,345|348,349|354,376|385,385|397,397|401,401|405,406|428,441|451,451 Q:2,14|23,23|28,35|38,39|43,47|49,63|65,65|67,67|74,80|82,85|91,91|95,96|98,99|102,113|116,117|119,120|122,141|146,169|174,189|195,196|226,230|232,234|239,240|242,245|248,250|252,254|269,271|275,276|278,281|292,294|296,307|311,311|314,323|325,337|343,343|346,347|350,353|377,384|386,396|398,400|402,404|407,427|442,450|452,453 ??HHHHHHHHHHHHS???-----S----EEEEEEEE??SS???HHHHH-HHHHHHHHHHHHHTT-T?E------EEEEEEE?TTSB?????S---SS?GG--GGGGTTSBGGGS??TT-SS-SSSHHHHHHHHHHHHHHTTT?-??EEEEHHHHHHTTTTHHHHHHHHHT----HHHHHHHHHHHHHHTT?????TT---------------------------??SEEEE?TTT??--EE?EEEE?-SSS?EEE??------------SSS???EE?TTSS?---------EEE?HHHHHHHHHHHS???B??EEHHHHSTTS-HHHHHHHHHHHHH?????B??EE??EEES---???-----????????????HHHHHTTS?HHHHHHHHHSS?TTS?EEE??STTHHHHHHHHHHHHHHHTTS----?????--???HHHHHHHHH?SS 1IVS|A PF01922.12_SRP19_seed 77 122 !Q:3,3|12,12|17,18|20,20|24,24|28,29|38,38|43,43|47,47|52,54|57,61|66,67|69,72|77,77|79,79|82,95|97,97|103,104 Q:0,2|4,11|13,16|19,19|21,23|25,27|30,37|39,42|44,46|48,51|55,56|62,65|68,68|73,76|78,78|80,81|96,96|98,102|105,121 EEE?GGGGBTTS?TTTT??S?TTT?BSS??HHHHHHHH-GGGT?EEE-EETT???TT??-??SSTT??E----EEEE?B?TT--------------S?BSSTT??SSHHHHHHHHHHGGGSH 1RY1|B PF01923.13_Cob_adeno_trans_seed 180 249 !Q:0,28|49,50|53,83|90,91|109,110|113,134|137,137|143,148|159,160|162,165|167,168|171,171|173,179|204,208|213,222|226,229 Q:29,48|51,52|84,89|92,108|111,112|135,136|138,142|149,158|161,161|166,166|169,170|172,172|180,203|209,212|223,225|230,248 ???????????---??????---??????HHHHHHHHHHHHHHHHHHHT--TS?----------------------------??HHHHHH--HHHHHHHHHHHHHHHHS--TT---?-------------????-HH-HHHHH------HHHHHHHHTT--S????S??BS?S-------SHHHHHHHHHHHHHHHHHHHHHHH-----HHHS?------?-?SHH----HHHHHHHHHHHHHHHHHHH 1NOG|A PF01924.11_HypD_seed 129 455 !Q:0,0|4,5|9,9|15,15|22,22|24,28|30,31|37,38|55,59|67,67|69,70|76,76|95,97|102,102|108,110|113,146|153,156|159,160|165,165|178,178|182,182|190,190|206,216|220,220|231,231|242,243|246,257|263,263|283,285|289,290|311,318|321,322|328,329|332,333|350,350|366,366|378,391|393,395|398,398|401,405|414,415|427,427|431,431|441,441|451,454 Q:1,3|6,8|10,14|16,21|23,23|29,29|32,36|39,54|60,66|68,68|71,75|77,94|98,101|103,107|111,112|147,152|157,158|161,164|166,177|179,181|183,189|191,205|217,219|221,230|232,241|244,245|258,262|264,282|286,288|291,310|319,320|323,327|330,331|334,349|351,365|367,377|392,392|396,397|399,400|406,413|416,426|428,430|432,440|442,450 ?HHH--HHH-HHHHH-HHHGGG?S-----S-?EEEEE??HHHHHHHHHTTGGGTS?----TTEEEEE?S??TTTTS?HHHHHHHHHHHHHHHHTT???EEEE?TTGGG???TT?-------------------------------?-HHHHHT----TT?-EEEE?SSHHHHHHHHHT?TTS?EEEEEEE?HHHHHHHHHHTHHHH-----------HTT?SSEEEEEEEE?HHHHHHHHHH--TT---------???SEEEE?HHHHHHHTTHHHHHHHHHH???EEE??SSHHHHHHHHHHHHHHHHHT-----???EE?-TTGGG??TT??HHHHHHHHHHEEEEEE-EETTTEEEEEEEEEE?STTTTSBHHHH???---???-----S???SS?TT---??HHHHHTTS??GGGSTTBTTTB?SSS?SSGGGTSTT?HHHHHHHTT--?? 3VYU|B PF01926.18_MMR_HSR1_seed 703 535 !Q:5,6|17,18|21,35|37,50|52,54|56,60|62,71|73,122|124,125|127,136|142,183|188,202|204,207|209,209|215,262|265,269|272,308|312,319|321,322|327,327|330,341|344,346|350,356|359,365|367,367|371,410|417,438|440,460|465,523|526,526 Q:0,4|7,16|19,20|36,36|51,51|55,55|61,61|72,72|123,123|126,126|137,141|184,187|203,203|208,208|210,214|263,264|270,271|309,311|320,320|323,326|328,329|342,343|347,349|357,358|366,366|368,370|411,416|439,439|461,464|524,525|527,534 EEEEE??TTGGGSHHHH--HH---------------H--------------H---H-----T----------B??----------------------------------????--?---??--S??S-??-------EEEEE------------------------------------------TTEE---------------E----E-EEESS?----------------------------------??-----------SS?---?SS?------------------------??--------??HHH--------H--HHHH-HH?-----------SE---EEE-------EE-------E-SSS--------------??-------?----------------HHHHHH----------------------H---------------------HHGG-----------------------------------------------------------GS-SEEEEEEE 1NVU|Q PF01928.16_CYTH_seed 51 296 !Q:0,1|9,11|22,28|44,44|46,50|53,53|59,60|66,88|107,108|112,113|122,146|148,148|152,153|163,184|188,189|202,204|208,215|227,238|248,248|261,269|279,281|283,286|288,288|296,296 Q:2,8|12,21|29,43|45,45|51,52|54,58|61,65|89,106|109,111|114,121|147,147|149,151|154,162|185,187|190,201|205,207|216,226|239,247|249,260|270,278|282,282|287,287|289,295 ??EEEEEEE??-HHHHHHHHTT-------SEEEEEEEEEEEEEE?S-----SS?HHHHT-?EEEEE-----------------------EEEETTEEEEEEEEEEEE??TTS??EEEEEEEE?------------------------S?HHH--HHHHHHHTT---------------------?EEE--EEEEEEEEEEEE---ETT--------EEEEEEEETTT------------EEEEEEEEE?SSGGGHHHHHHH---------HHHHHHHHT???B?--?S?HHHHHHH- 3TJ7|A PF01929.12_Ribosomal_L14e_seed 53 79 !Q:5,5|16,20|23,24|44,44|59,60|71,71 Q:0,4|6,15|21,22|25,43|45,58|61,70|72,78 EEEEE?GGGEEEEEEE??-??SS??STHHHHHHHHHTTTHHHHT?HHHHHHHHHHHHHT??HHHHHHHHHH-HHHHHHH 3J39|M PF01930.12_Cas_Cas4_seed 57 211 !Q:10,10|20,20|29,29|35,36|50,50|54,55|80,88|91,101|106,107|109,113|118,118|122,122|135,141|157,160|164,168|172,173|185,186|193,195|199,199|202,202|208,208 Q:0,9|11,19|21,28|30,34|37,49|51,53|56,79|89,90|102,105|108,108|114,117|119,121|123,134|142,156|161,163|169,171|174,184|187,192|196,198|200,201|203,207|209,210 TEEEHHHHTS?HHHHHHHHH-HHHGGGGG?HHHHH--HHHHHHHHHHHHS?EEE--EEEEEEEEEETTEEEEEEEEEEEE?--??????EE-----------EEEE??S??---TTSS?HHH-HHHHHHHHHHHT------?SEEEEEEEETTEEEE----EEE?????HHH--HHHHHHHHHTT?-SSSSST---TSG-GG?TTGGG?TT 4IC1|A PF01931.13_NTPase_I-T_seed 20 177 !Q:1,3|18,18|21,24|29,33|36,36|39,40|63,63|75,78|80,82|93,93|96,100|106,108|111,112|121,121|123,125|135,143|155,155|173,173 Q:0,0|4,17|19,20|25,28|34,35|37,38|41,62|64,74|79,79|83,92|94,95|101,105|109,110|113,120|122,122|126,134|144,154|156,172|174,176 S???HHHHHHHHHHHHHH?TT?-??EEEE?????SS?SS??SHHHHHHHHHHHHHHHHHHSTT?SEEEEEEEEEE----T---TEEEEEEEEE?SS----?EEEEE???EE??HHHHHHHT-T???HHHHHHHHH?????????HHHHHHTTTSS?HHHHHHHHHHHHTHHHH?GGG 1ZWY|A PF01933.13_UPF0052_seed 32 453 !Q:4,5|20,36|45,49|61,62|64,66|77,79|81,85|94,94|96,152|158,158|174,174|188,188|191,192|198,200|203,204|212,216|219,228|239,289|291,291|293,293|301,309|313,316|326,326|332,332|335,335|356,358|365,366|369,370|373,373|376,381|384,385|398,398|402,402|409,409|411,414|426,427|429,432|441,441|447,449 Q:0,3|6,19|37,44|50,60|63,63|67,76|80,80|86,93|95,95|153,157|159,173|175,187|189,190|193,197|201,202|205,211|217,218|229,238|290,290|292,292|294,300|310,312|317,325|327,331|333,334|336,355|359,364|367,368|371,372|374,375|382,383|386,397|399,401|403,408|410,410|415,425|428,428|433,440|442,446|450,452 EEEE??HHHHHHHHHHHTTS-----------------SEEEEEEE?????SHHHHHHHHHT?-S???HHHHHHHHHH-??S----?HHHHHHHH?B??-----------------------------------------------------??SSSTT?BHHHHHHHHHHHHHS?HHHHHHHHHHHHT?SS--EEEES--?SS??EEEEEET-----TS---------?EEESTTTSGG---------------------------------------------------G?S?EEEEEEE---------STT????HHHHHHHHH?SEEEE?SS?IIIIIHHHHTSTTHHHHHHH??-SEEEEE??SB??TT-TS------TT??HHHHHHHHHHHH?SSS?SEEEEE?S-???HHHHHHHHTTT??B????HHHHHHTT?EEEEE???EES 3C3E|A PF01934.12_DUF86_seed 147 196 !Q:10,58|61,66|95,95|99,102|107,109|122,122|126,126|143,143|147,149|160,160|163,185|196,196 Q:0,9|59,60|67,94|96,98|103,106|110,121|123,125|127,142|144,146|150,159|161,162|186,195 HHHHHHHHTS----------------------------------------------???SS------SHHHHHHHHHHHHHHHHHHHHHHHHHHH-HTT????SSGG---GHHHHHHHTTSS?HHH-HHHHHHHHTTHHHHHT?GGG-??HHHHHHHHHH-TH-----------------------HHHHHHHHHH- 1WTY|A PF01935.12_DUF87_seed 46 378 !Q:2,3|7,7|9,10|13,13|15,30|34,34|36,38|40,44|48,49|67,75|79,82|90,92|98,110|115,115|126,128|132,175|177,180|184,187|198,218|222,222|224,225|229,230|247,248|251,270|275,275|290,290|316,330|336,344|347,347|349,350|355,359|361,361 Q:0,1|4,6|8,8|11,12|14,14|31,33|35,35|39,39|45,47|50,66|76,78|83,89|93,97|111,114|116,125|129,131|176,176|181,183|188,197|219,221|223,223|226,228|231,246|249,250|271,274|276,289|291,315|331,335|345,346|348,348|351,354|360,360|362,377 EE--EEE?T--TS?E----------------EEE?T???E-----EEE??TTSSHHHHHHHHHHHHH---------TTT?--?EEEEESS?-?SHHHH-------------HHTT?EEEETTSGGG???TTS?--------------------------?????????????????H----HHH----HHHHHHHHHH---------------------HHS?S??HHH--HHHHHHHHHHHHHHTT??TT------------------??GGGS?GHHHHHHHHHHTTT?HHHHHHHHHHHHHHHTSTTHHHHSS????--------???SSEEE---------EE?G--GGTT-----S?HHHHHHHHHHHHHHHH 4AG6|A PF01936.13_NYN_seed 149 278 !Q:18,23|27,29|31,32|43,53|57,61|70,87|90,95|97,103|108,110|114,119|124,135|138,144|147,152|155,166|168,171|184,185|188,191|198,202|205,207|220,222|229,243|246,246|249,249|252,257|264,264|269,276 Q:0,17|24,26|30,30|33,42|54,56|62,69|88,89|96,96|104,107|111,113|120,123|136,137|145,146|153,154|167,167|172,183|186,187|192,197|203,204|208,219|223,228|244,245|247,248|250,251|258,263|265,268|277,277 EEEEEEEHHHHHHHHHHH------HSS?--B-?HHHHHHHHTT-----------TEE-----EEEEEEEE?-------------????HH------H-------HHHH---HHH------HHHT----------?-EE-------EE??????SS---------???S-???HHHHHHHHHHHG--GG?---SEEEEE???--GG---GHHHHHHHHHHH?-?EEEEEE--------?------GG-GS?HH------HHHHSS-EEEE-------?S 2QIP|A PF01937.14_DUF89_seed 86 530 !Q:10,10|22,25|29,29|33,44|60,61|70,70|72,76|85,86|91,103|112,112|138,141|147,148|156,156|173,174|188,198|218,219|225,228|238,242|255,257|261,262|274,284|287,287|290,293|299,300|312,312|320,320|324,324|335,336|341,341|355,355|360,362|365,386|404,405|416,426|428,429|431,431|437,438|446,447|460,461|463,463|478,478|483,485|488,489|497,498|504,505|512,513|516,522 Q:0,9|11,21|26,28|30,32|45,59|62,69|71,71|77,84|87,90|104,111|113,137|142,146|149,155|157,172|175,187|199,217|220,224|229,237|243,254|258,260|263,273|285,286|288,289|294,298|301,311|313,319|321,323|325,334|337,340|342,354|356,359|363,364|387,403|406,415|427,427|430,430|432,436|439,445|448,459|462,462|464,477|479,482|486,487|490,496|499,503|506,511|514,515|523,529 HHHTHHHHHH-HHHHHHHHHHH----TTS?SSS------------HHHHHHHHHHHHHHH--HHHHHHHT?B?????HHHHHHTT??THHH-------------HHHHHSTT?BTTBSBHHHHHHHHHHHHHHHHHHS----TTTTT??TTHHHHH-HHHHTTHHHHHHHHHH--HHHHHHHHHHHHH???----????HHHHHHHHHHHHHHHHGGG??HHHHT--??SHHHHHSHH-----HHHHHHHHHTTE---EEE?-HHHHHHHHHHH-----------HH?SS????EEEEE??BSTHHHHHHHH-HHHHHHH-HTS?SEEEEEEBSS??TTTB?BHHHHHHHHHHHH?TTTS???ST----------------------TSHHHHHHHHHHHHHHH--HHHHTSEEEE-----------E-?G-GGGSS??GGGSSTT??SSSHHHHHHHHT--T?SEEEEEHHHHHHHH-HTTB???TT??HHHHTGG--GGTSS??EEEEEE??SS??????-TTHHHHH 2FFJ|A PF01938.15_TRAM_seed 30 83 !Q:1,2|11,12|16,18|29,41|50,55|57,59|61,61|71,71|73,74|76,76|82,82 Q:0,0|3,10|13,15|19,28|42,49|56,56|60,60|62,70|72,72|75,75|77,81 S??TTEEEEEE??EEE---TTTEEEEEET-------------TEEEEEES?----?T---T?EEEEEEEEE?S--S?EEEEE? 1YVC|A PF01939.11_DUF91_seed 4 234 !Q:2,2|32,32|36,36|41,41|43,43|45,45|48,48|53,53|56,60|73,73|77,77|94,106|117,117|122,122|125,125|145,145|149,149|156,156|159,159|161,161|180,181|183,183|192,192|194,194|206,206|211,233 Q:0,1|3,31|33,35|37,40|42,42|44,44|46,47|49,52|54,55|61,72|74,76|78,93|107,116|118,121|123,124|126,144|146,148|150,155|157,158|160,160|162,179|182,182|184,191|193,193|195,205|207,210 HT?EEEEEEEEEEEEESSSEEEEEEEEEEEEE?TTS?EEEE?S-S?SS?SEEE?TT?----EEEESSEEEEEE?SSS?EEEEEEEEEEEEEEEE?????????????HHHHHHHHHH?GGGT?TT?EEEEEEEEETTEEEEEEEE?TTS?EEEEEE?SS?B?HHHHHHHHHHHHHHHHHH?-S?EEEEEEES?B?HHHHHHHHHHT?EEEE???????---????????????? 2VLD|A PF01941.14_AdoMet_Synthase_seed 48 434 !Q:0,5|11,11|14,15|28,28|56,56|59,61|71,72|86,86|96,97|101,102|108,108|110,117|134,134|137,138|143,143|152,154|164,164|167,169|171,171|173,173|177,177|185,186|208,208|239,240|264,270|276,280|285,285|288,291|298,299|305,305|311,312|319,320|326,326|330,336|340,340|344,344|364,364|367,367|377,378|386,386|399,403|420,420|432,432 Q:6,10|12,13|16,27|29,55|57,58|62,70|73,85|87,95|98,100|103,107|109,109|118,133|135,136|139,142|144,151|155,163|165,166|170,170|172,172|174,176|178,184|187,207|209,238|241,263|271,275|281,284|286,287|292,297|300,304|306,310|313,318|321,325|327,329|337,339|341,343|345,363|365,366|368,376|379,385|387,398|404,419|421,431|433,433 ???---EEEEE?SS??STTSSEEEEEEE?TTSHHHHHHHHHHHHHHHHHHHHHHHH-SS???EEEEEEEEE??EEEEETTEEEEEE?EEEEEEEEE??EEE?-SSSEE-E------??HHHHHHHHHHHHHHHH?SS??TTTS-EEEEEEEE???HHHHHHHTT?SS---S?B?SSS?EEEEEES??HHHHHHHHHHHHHHSHHHHHH?TTEEEEEEEEEEEETTEEEEEEEEEEEGGG??SHHHHHHHHHHHHHHHHHHHHHH-----?-TTSEE-----EEEE?TT?---BGGGTB??EESSS?GGGGT??EETTSS??TTSSB?TTS???????TTB?TTT?HHHHHHHHHHHHHHHHHHH?TT-EEEEEEEEE??TTSBTTS?SEEEEEEEESSS--???HHHHHHHHHHHHHHHH?HHHHHHHHHTT?S 4L2Z|A PF01946.12_Thi4_seed 8 262 !Q:23,24|39,39|43,43|48,48|53,54|59,60|64,66|82,84|87,87|95,95|130,130|135,135|150,152|158,161|168,168|170,170|176,176|180,182|187,189|191,191|195,195|203,204|208,208|211,218|220,220|232,232|235,235|244,244|254,255|257,258|260,261 Q:0,22|25,38|40,42|44,47|49,52|55,58|61,63|67,81|85,86|88,94|96,129|131,134|136,149|153,157|162,167|169,169|171,175|177,179|183,186|190,190|192,194|196,202|205,207|209,210|219,219|221,231|233,234|236,243|245,253|256,256|259,259 HHHHHHHHHHHHHHTTEESEEEE??SHHHHHHHHHHHHH?TTS?EEEE?SSSS??TTTT??STT???EEEETTTHHHHHHTT???EE?SSEEEES?HHHHHHHHHHHHHTSTTEEEETTEEEEEEEEESS?SSSS?EEEEEEEEEHHHHT?--TTSSS????EEEEES?B?TTSSB?TTS???EEEE???S?SSS?SHHHHHH--HHH?TT????????B?HHHHHHHHHHH?EE?TTSBTEEE?THHHHHHHT??B??S?? 3ZYX|A PF01947.11_DUF98_seed 20 182 !Q:2,3|5,5|14,14|16,16|18,18|31,34|36,45|53,54|56,62|64,64|76,81|99,99|109,109|112,112|122,123|136,137|146,146|149,149|175,177|180,181 Q:0,1|4,4|6,13|15,15|17,17|19,30|35,35|46,52|55,55|63,63|65,75|82,98|100,108|110,111|113,121|124,135|138,145|147,148|150,174|178,179 HH??S?HHHHHHHH-H?S?EEEEEEEEEEEE--??H----------HHHHHHT??T-------T?EEEEEEEEEEE------TTEEEEEEEEEEEGGGS?HHHHHHHHT?SS?HHHHHHHTT??BEEEEEEEEEEE??HHHHHHHT?SS?EEEEEEEEEEETTEEEEEEEEEEEG---GG?? 2NWI|A PF01948.13_PyrI_seed 60 109 !Q:0,8|21,21|23,30|39,46|48,48|63,63|72,76|87,87|90,90|105,108 Q:9,20|22,22|31,38|47,47|49,62|64,71|77,86|88,89|91,104 ?????????SSEEEEEEEETT?H--------HHHHHHHT-??-????S?EEEEEEEEETTTEE-EEEEEEET??-??HHHHHGGGGT?TT?EEEEEETTEEEEEE???? 2YWW|A PF01949.11_DUF99_seed 29 204 !Q:13,20|23,23|35,35|46,46|49,49|51,51|63,63|85,86|95,97|105,107|118,118|124,124|126,126|135,138|142,155|166,166|178,178|184,184|199,203 Q:0,12|21,22|24,34|36,45|47,48|50,50|52,62|64,84|87,94|98,104|108,117|119,123|125,125|127,134|139,141|156,165|167,177|179,183|185,198 GGGSEEEEEEEEE?-------SS?EEEEEEEEETT-EEEEEEEEEE?TT?S?HHHHHHHHHTT?TTTTTEEEEEESSSEETTTEE??HHHHHHHH???EEEEESS???HHHHHHHHTT-STTHH-H-HHHHHHHT-???EEE--------------TTEEEEEESS?HHHHHHHHHHH?SSSSS?HHHHHHHHHHHHHH????? 2QH9|A PF01950.11_FBPase_3_seed 33 401 !Q:0,0|10,12|19,21|41,41|62,62|65,65|70,70|90,90|97,98|102,103|105,106|111,111|120,127|130,130|141,141|155,155|159,159|165,165|171,171|181,185|220,220|223,228|230,234|239,243|253,253|256,256|262,262|267,268|278,278|280,281|290,290|295,295|298,300|312,316|320,320|322,322|333,333|341,341|346,346|370,370|375,376|380,380|382,385|394,397 Q:1,9|13,18|22,40|42,61|63,64|66,69|71,89|91,96|99,101|104,104|107,110|112,119|128,129|131,140|142,154|156,158|160,164|166,170|172,180|186,219|221,222|229,229|235,238|244,252|254,255|257,261|263,266|269,277|279,279|282,289|291,294|296,297|301,311|317,319|321,321|323,332|334,340|342,345|347,369|371,374|377,379|381,381|386,393|398,400 ?EEEEEEEEE???BTTTTS???HHHHHHHHHHHHHHHHTTS?SEEEEEEETTEEEEEEEESS?TT?HHHH-HHHHHHHHHHHHHTTTTTT?BTTTTT??SSS??S??TTSS?EEEEEEEE-?-----?SS?EEEEEEEESB?GGGGHHHHHHHHH?TTT?THHHH?GGGTT?EEEEEEETT-----TTEEEEEEETTTHHHHHHHHTSTTTEEEEEEEET-TT??----E-----EEEE?????EEETTEEES?SS?EEEEE?STTS??HHHHHHTTS-S??EEEESGGG?EEEE?EE???SEEETTTTEEE?????GGG?S?EEEEEEEEEE-TTEEEEE-EETT?SHHHHHHHHHHHHHHHHHHTTTT?TTTB??GGG?S??-?HHHHHTTS????HHH 3T2F|A PF01951.11_Archease_seed 96 257 !Q:3,7|17,17|37,39|42,55|57,58|60,62|69,69|92,94|96,102|106,106|110,148|160,165|168,177|179,180|182,184|186,213|217,217|222,247|256,256 Q:0,2|8,16|18,36|40,41|56,56|59,59|63,68|70,91|95,95|103,105|107,109|149,159|166,167|178,178|181,181|185,185|214,216|218,221|248,255 EEE???--SSEEEEEEE?SSSHHHHHHHHHHHHHHHS-??TT??-----------?S-?E---EEEEEE-ESSSHHHHHHHHHHHHHHHHHT-??S???---?EEE-EEE?--------------------------------------SSSEEEEEEEE????-?TT??--??????B??S???E----------------------------EEE-ETTE--------------------------EEEEEEEE? 1J5U|A PF01954.11_DUF104_seed 41 74 !Q:0,3|18,22|31,69|73,73 Q:4,17|23,30|70,72 ????EEEEEETTEEEESS?????TTEEEEEE????????-----???????-----------------??GGG? 2NWT|A PF01957.13_NfeD_seed 29 170 !Q:0,95|97,103|109,109|115,116|118,121|123,123|126,127|145,146|148,148|151,151|168,169 Q:96,96|104,108|110,114|117,117|122,122|124,125|128,144|147,147|149,150|152,167 -------------?----------------------------------------------------------------?????????????????-G-------GGGTT?EEEEE--E?---B?SS??EEEETTEEEEEEESSTT??B?TT?EEEEEEEETTEEEEEE?? 2K5H|A PF01958.13_DUF108_seed 65 115 !Q:5,5|7,8|25,26|37,52|55,56|64,64|66,67|79,84|96,96 Q:0,4|6,6|9,24|27,36|53,54|57,63|65,65|68,78|85,95|97,114 GGTTS?E--EEEEEEHHHHHHHSTT??HHHHHHHHHH----------------SS??EEEEEEE-S?-SSEEEEEEEEE------TTEEEEEEEEE?EETTEEEEEHHHHHHHHH 1H2H|A PF01960.13_ArgJ_seed 139 569 !Q:6,8|12,28|30,34|40,41|44,46|56,58|61,62|73,79|83,83|85,88|99,101|103,103|124,125|127,138|140,149|151,151|161,165|176,182|184,192|194,201|204,206|211,213|218,219|222,222|225,225|231,234|237,240|243,246|255,258|261,275|285,286|290,290|307,307|311,313|315,316|325,326|329,329|332,345|349,361|381,381|384,385|411,411|422,424|434,434|436,442|445,445|449,449|453,453|458,466|468,471|473,485|490,499|513,521|523,523|531,537|539,539|542,543|552,554|563,568 Q:0,5|9,11|29,29|35,39|42,43|47,55|59,60|63,72|80,82|84,84|89,98|102,102|104,123|126,126|139,139|150,150|152,160|166,175|183,183|193,193|202,203|207,210|214,217|220,221|223,224|226,230|235,236|241,242|247,254|259,260|276,284|287,289|291,306|308,310|314,314|317,324|327,328|330,331|346,348|362,380|382,383|386,410|412,421|425,433|435,435|443,444|446,448|450,452|454,457|467,467|472,472|486,489|500,512|522,522|524,530|538,538|540,541|544,551|555,562 EEEEEE???SST-----------------T?-???EEEEE--EE---EEEEEEEEE???TT??HHHHHHHHHH-------TTS-E----EEEEEEEEEE???S?HHHHHHHHHHHHHHHHHHHT??G------------G----------G?EEEEEEESS???-?HHHHHHHHHH--???-?S---------S--------SB--?HHHH---HHHS?-SS?SS?EEEEE----EE----TT----EEEEEEEE--??SS?????-------???EEEEEEEEE??HHH-HHHHHHHHHHHTGGGB?SSS???S??EEEEEEEE--EE-EE------------??HHH-------------HHHHHHHHHHHHHHHHHHS?TT??SEEEEEEEEESSHHHHHHHHHHHHH?HHHHHHHHTT???HHHHHHHHH-T?------TT?TTS?TTT?EEEE---------T----T-------------EEEE??????????HHHHHHHHHHTTS---------S-EEEEEEE?-----?S-SS--EEEEEEEE???HHHHHHHH??--?? 2VZK|A PF01964.13_ThiC_seed 113 477 !Q:9,11|25,38|41,45|47,48|51,54|57,58|73,76|79,81|84,88|94,95|102,109|125,125|131,133|136,136|149,150|153,153|157,157|164,167|173,173|177,178|194,195|200,200|203,204|213,215|217,217|220,223|239,240|258,258|263,264|267,268|276,276|298,299|305,307|309,310|328,329|334,335|338,338|341,341|344,344|361,362|366,368|375,377|401,403|408,408|422,422|432,432|440,476 Q:0,8|12,24|39,40|46,46|49,50|55,56|59,72|77,78|82,83|89,93|96,101|110,124|126,130|134,135|137,148|151,152|154,156|158,163|168,172|174,176|179,193|196,199|201,202|205,212|216,216|218,219|224,238|241,257|259,262|265,266|269,275|277,297|300,304|308,308|311,327|330,333|336,337|339,340|342,343|345,360|363,365|369,374|378,400|404,407|409,421|423,431|433,439 SHHHHHHTT???HHHHHHHHHHTTT------------??SS?????S??SS????SS??HHHHHHHHHTTSEE????TT?--TT?????EETTS??EEEEEE????????HHHHHHHHHHHHHHT?SEEEE???ST-THHHHHHHHHTT?-SS?EEE?THHHHH----HHTTT?GGG??HHHHHHHHHHHHHHT??EEEE?TT??GGGGGGGG---G?SS????HHHHHHHHHHHHHTS??HHHHTHHHHHHHHTTTT?EEEE??TT??SSGGGTT?HHHHHHHHHHHHHHHHHHHTT??EEEEE-??B??GGGHHHHHHHHHHHTTT??EEEE??BS?SS?TT?HHHHHHHHHHHHHHHT??EEE???TTTTTS???HHHHHHHHHHHHHHHHHHHHHTT--?TTHH-HHHHHHHHHHHTT?HHHHHHTSS?HHHHHHH?????????--?????????????????--??????? 3EPN|A PF01965.19_DJ-1_PfpI_seed 39 221 !Q:10,15|19,19|23,34|39,39|45,46|50,58|64,65|69,69|76,86|100,100|102,103|112,112|120,121|123,142|144,144|147,149|155,161|168,168|171,174|177,177|179,182|187,198|203,203|220,220 Q:0,9|16,18|20,22|35,38|40,44|47,49|59,63|66,68|70,75|87,99|101,101|104,111|113,119|122,122|143,143|145,146|150,154|162,167|169,170|175,176|178,178|183,186|199,202|204,219 EEEEEESSSE------EEE?TTS-----------?EEEE?EEGGG??GGG--------?SEEEE??BSH-HHHHTT?----------HHHHHHHHHHHHT-T??EEEETTTT-HHHHHHT??T--------------------T?EE???GGGHH-------HHHHTT?EE??--SS?E----EETT------------EEEE?SGGGHHHHHHHHHHHH? 1QVV|A PF01966.17_HD_seed 154 213 !Q:22,29|33,43|61,61|66,94|106,106|110,112|115,121|137,137|146,147|158,161|165,180|184,184|195,196|201,202 Q:0,21|30,32|44,60|62,65|95,105|107,109|113,114|122,136|138,145|148,157|162,164|181,183|185,194|197,200|203,212 HHHHHHHHHHHHHHHHHHHHHH?-------GGG--------???HHHHHHHHHHHHHTTTT?BTTB-----------------------------HHHHHTHHHHH?TTS???HH-------HHHHHHHHHHHHHTT?HHHHHHTT??HHHHHHHHHH----HHH????????????--??SSS?GGGGGGGGSS??TTTS??HHHHHHHHHH 3DJB|A PF01967.16_MoaC_seed 19 154 !Q:0,3|7,8|21,22|33,34|36,37|39,40|63,69|76,83|106,107|130,130|132,140|151,153 Q:4,6|9,20|23,32|35,35|38,38|41,62|70,75|84,105|108,129|131,131|141,150 ????STT??EEEEEEEEEEEE??HHHHHHHHTT??T--T??HHHHHHHHHHHHHHTHHHHSTT???-???SEEEEE--------EEEEGGGTEEEEEEEEEEEESS??HHHHHHHHHHHHHHHHHHHGGG?S?-------?EEEEEEEEEE??? 1EKR|A PF01968.13_Hydantoinase_A_seed 61 546 !Q:0,1|4,20|33,70|73,73|78,78|92,96|98,99|111,115|118,118|120,128|136,136|139,139|151,173|187,189|192,193|199,199|204,204|212,214|217,289|302,302|306,307|309,311|315,317|332,333|338,338|342,378|402,487|493,494|512,514|526,526|546,546 Q:2,3|21,32|71,72|74,77|79,91|97,97|100,110|116,117|119,119|129,135|137,138|140,150|174,186|190,191|194,198|200,203|205,211|215,216|290,301|303,305|308,308|312,314|318,331|334,337|339,341|379,401|488,492|495,511|515,525|527,545 --EE?????????????????SHHHHHHHHHHH--------------------------------------TT?EEEE?SSSSEEEHHHHHH?????B??SSHHHHHHHHH-----HT?S---------SEEEEEE?SS?EEEEEEETTEE--------------------???SSHHHHHTTTSEE???SS??BGGGG?SEEE-ETTEEEE???SS-----------------------------------------------------------------------??BHHHHHHHTTSS?GGG??S?-?TTS???SHHHHHHHHHHTTT??TTTS?HHH-------------------------------------HHHHHHHHHHHHHHHHHHHHHHH--------------------------------------------------------------------------------------HHHHT??EEEEESTTHHHHHHHTT---TSEEEEHHHHH?HHHHTSHHHHHHHHHHHHH- 3C0B|A PF01974.12_tRNA_int_endo_seed 78 147 !Q:14,14|16,16|21,21|24,29|38,44|47,48|53,54|60,71|73,73|81,103|119,119|127,132|136,143|147,147 Q:0,13|15,15|17,20|22,23|30,37|45,46|49,52|55,59|72,72|74,80|104,118|120,126|133,135|144,146 HHHHHHHHHHHHHT-T?EEEE?GG------GTSSEEEE?------SS??TTTS??SEEEE------------E-EETTSEE----------------------?THHHHHHHHHHHHTT?EEEEEEE-----?TTS?-------EEE- 4FZ2|A PF01975.12_SurE_seed 133 326 !Q:0,0|6,6|9,9|11,14|16,16|27,27|31,33|35,35|37,38|47,48|52,53|55,57|60,60|64,64|68,71|73,95|98,103|108,108|111,113|126,126|130,148|151,152|161,163|167,167|171,171|185,186|191,194|198,198|200,224|226,228|230,240|242,245|256,256|262,262|265,276|278,281|290,291|294,299|301,302|306,309|314,314|316,320 Q:1,5|7,8|10,10|15,15|17,26|28,30|34,34|36,36|39,46|49,51|54,54|58,59|61,63|65,67|72,72|96,97|104,107|109,110|114,125|127,129|149,150|153,160|164,166|168,170|172,184|187,190|195,197|199,199|225,225|229,229|241,241|246,255|257,261|263,264|277,277|282,289|292,293|300,300|303,305|310,313|315,315|321,325 ?EEEEE?SS?T----T?HHHHHHHHHH-TTT---S-E--EEEEEESS??TTS??S???SS?EEE-EEE----E-----------------------TT------EEEE-TT-??HHHHHHHHHHTT-TTT?-?-------------?--SE--EEEEEESS???GGG-GGG?HHHHHHHHHHHTT??EEEE----EEE?S-------------------------S---S?-------?--H----HHHHHHHHHH-HHHHH-HH??-?--------T----TEEEEEEE--ES------S?-GGG?--?EEEE?B????-SSEEE 2E69|A PF01977.11_UbiD_seed 155 666 !Q:4,4|9,15|20,20|22,22|24,25|29,32|41,48|52,59|61,69|75,75|77,79|82,82|84,91|93,93|96,96|98,98|101,105|108,115|123,123|125,131|148,150|152,160|164,183|188,189|191,191|199,199|204,207|209,210|213,213|215,217|219,219|223,224|226,231|234,255|261,263|265,265|267,271|273,273|278,280|283,283|285,285|287,291|293,293|299,301|303,303|309,309|314,316|319,322|327,351|355,357|366,367|376,376|378,385|389,389|399,402|405,406|411,411|413,415|419,419|425,425|435,437|439,446|451,452|454,454|456,457|460,460|465,465|468,470|473,476|488,488|490,491|493,495|498,503|507,509|524,526|533,533|535,535|537,540|546,547|555,555|562,564|566,573|577,585|601,603|606,607|613,616|618,618|622,622|625,625|636,640|642,643|647,651|661,664 Q:0,3|5,8|16,19|21,21|23,23|26,28|33,40|49,51|60,60|70,74|76,76|80,81|83,83|92,92|94,95|97,97|99,100|106,107|116,122|124,124|132,147|151,151|161,163|184,187|190,190|192,198|200,203|208,208|211,212|214,214|218,218|220,222|225,225|232,233|256,260|264,264|266,266|272,272|274,277|281,282|284,284|286,286|292,292|294,298|302,302|304,308|310,313|317,318|323,326|352,354|358,365|368,375|377,377|386,388|390,398|403,404|407,410|412,412|416,418|420,424|426,434|438,438|447,450|453,453|455,455|458,459|461,464|466,467|471,472|477,487|489,489|492,492|496,497|504,506|510,523|527,532|534,534|536,536|541,545|548,554|556,561|565,565|574,576|586,600|604,605|608,612|617,617|619,621|623,624|626,635|641,641|644,646|652,660|665,665 HHHH-HHTT--?----EEEE?S?B?-TBT----HHHHHHHH--------HHT--------T--???----EEEES?B---TT?S--------S?EE-E?TT---?-SH--------HHHHHTT-T??-----SGGGHHHHHHHHHHHH-??S??-------STT?????????????????--?EEES--S?GGGSEEE-EGGG??--G--GG-S???B?STT??S-----?EE??-------------------?EEEEE--?S-S?----S?EEEE???EE-E?S-----S-SEEEE???S-SSHHH-HHHH---HH----HHHS-------------------------TTS--?EEEEEEES??HHHHHHHH-S?---??--TTS?HHHHHHHHH----SS??EEEE?S---SSS?EEETT?SEEEEEEEE---E--------EEEE--E-E??EE?TTSE-EE-??EE----EEEEEEEEEEE?T--T-??EE??-???SSS--?HHHHHHHHHHHHHH---HHHHHH?T-T----EEEEE??GGGTTTS-EEEEEE???S--------TTH---------HHHHHHHHHHSSGGG---SS??EEEEE----E-TTS?TT?HHHHHHHHHH-----S??HHH-----HEEEEEEEE?--?T 2IDB|A PF01978.14_TrmB_seed 51 80 !Q:0,2|13,13|19,21|30,31|40,40|42,43|59,61|63,68|70,71|76,77 Q:3,12|14,18|22,29|32,39|41,41|44,58|62,62|69,69|72,75|78,79 ??-HHHHHHHTTS?SHHHH---HHHHHHHS??SSSTTSSS?S??HHHHHHHHHTSEEEE?-?T------T?-EEEE??HH 2OQG|A PF01979.15_Amidohydro_1_seed 58 500 !Q:4,4|7,9|15,15|17,17|22,55|70,70|78,80|83,91|93,114|125,126|140,142|144,144|156,156|159,195|203,205|221,221|227,228|231,231|234,235|246,247|260,295|306,306|308,312|319,319|325,325|343,344|354,360|366,366|383,383|386,388|394,394|397,397|414,415|417,417|420,421|425,425|427,460|480,480|488,488|493,494|499,499 Q:0,3|5,6|10,14|16,16|18,21|56,69|71,77|81,82|92,92|115,124|127,139|143,143|145,155|157,158|196,202|206,220|222,226|229,230|232,233|236,245|248,259|296,305|307,307|313,318|320,324|326,342|345,353|361,365|367,382|384,385|389,393|395,396|398,413|416,416|418,419|422,424|426,426|461,479|481,487|489,492|495,498 EEEE?EE---EEEEE?S?THHH----------------------------------HHHHHHTEEEEEEE?SSSSHHH---HH???----??H----------------------HHHHHHHHHH--HTTSSSEEEEEEE???S?HHHHHHHHHHT?SE-------------------------------------EEEEGGG???HHHHHHHHHHHHHHT?EEEEE??TT?SS??HHHHHHHHTT??EEETTTTSTTSS------------------------------------STTTGGGGGG?T-----TEEEEE?STTSS?BTTHHHHHHHHHHHTTT??TTSHHHHTT-------HHHHS?HHHHHHHHHHHHHTSS?EE???TTSSS?TT?HHHHHHHHHHHHHHHH-?S?TT??SSS?H----------------------------------HHHHHHHGGGTHHHHHHTT?TTTSSSS?TTSB??EEEE? 1FWI|C PF01980.11_UPF0066_seed 184 209 !Q:5,5|7,8|12,14|16,25|27,27|34,34|38,41|51,51|60,120|125,126|128,129|131,133|135,135|145,146|155,155|163,164|166,186|189,189|197,199|201,203|206,206|208,208 Q:0,4|6,6|9,11|15,15|26,26|28,33|35,37|42,50|52,59|121,124|127,127|130,130|134,134|136,144|147,154|156,162|165,165|187,188|190,196|200,200|204,205|207,207 SGGGS?S?-TTT--?T----------T?EEEEEE?TTT?--?TTTTTTGGG?SEEEEEEE???????--------------------?????-------??????-?-------??-????GGGS??S??S---S?EEEEEEEEE--EEEEETTE-EEEEEEE??S--------------------?TT?EEEEEEE-??H---HH-H? 1XQB|A PF01981.11_PTH2_seed 69 159 !Q:0,0|12,14|34,42|46,46|48,77|85,85|89,90|98,99|116,117|124,124|131,131|156,156|158,158 Q:1,11|15,33|43,45|47,47|78,84|86,88|91,97|100,115|118,123|125,130|132,155|157,157 ?EEEEEEEEGGG???HHHHHHHHHHHHHHHHHHH---------HHH?H------------------------------HHHHHHH-HTT??EEEEEES--SHHHHHHHHHHHHHTT??EEEEEE?SSSSEE-EEEEEEEEEEEEEHHHHHHHHTTS?B? 1XTY|A PF01982.11_CTP-dep_RFKase_seed 44 135 !Q:1,16|25,25|27,33|38,38|41,41|43,43|54,55|59,60|63,67|70,71|82,86|91,96|103,107|114,128 Q:0,0|17,24|26,26|34,37|39,40|42,42|44,53|56,58|61,62|68,69|72,81|87,90|97,102|108,113|129,134 E????????????????HHHHHHHS?S???????EEEE?GG-G-HHHHHHHHHS??EEE??EE-????EE??EEEEEEEETT-----EEEE------EEEESS???-?SEEEEE???????????????EEEEEE 2VBS|A PF01983.11_CofC_seed 3 223 !Q:0,0|6,8|11,11|21,21|43,43|46,50|60,60|63,64|71,74|76,76|85,87|91,92|94,94|99,99|101,102|105,106|116,116|119,120|127,127|131,131|139,139|143,147|164,165|169,171|176,179|191,192|195,195|202,212|220,220 Q:1,5|9,10|12,20|22,42|44,45|51,59|61,62|65,70|75,75|77,84|88,90|93,93|95,98|100,100|103,104|107,115|117,118|121,126|128,130|132,138|140,142|148,163|166,168|172,175|180,190|193,194|196,201|213,219|221,222 ?EEEEE???TT-TTGGGTTTS?HHHHHHHHHHHHHHHHHHHHH-TT----?SEEEEEESS?TS??SSEEEE??--S?HHHHHHHH---HHH??S?EEEE?S??TT??HHHHHHHTT?SS--SEEEEE?GGG?EEEEEES?GGG?????SSSHHHHHHHHHHTTT??EEE???TTTT????SHHHHHHHHHH??SH-HHHHHH-----------TTEEEEE?SS 3CGX|A PF01984.15_dsDNA_bind_seed 62 133 !Q:0,13|16,29|42,51|64,64|78,78|97,99|101,101|103,103|118,132 Q:14,15|30,41|52,63|65,77|79,96|100,100|102,102|104,117 ??????--??????SS------------??THHHHHHHHHHH----------HHHHHHHHHHHB?HHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHT???S?B?HHHHHHHHHHHTTS????----??????? 2K6B|A PF01985.16_CRS1_YhbY_seed 144 113 !Q:0,2|17,20|22,26|29,29|33,34|56,62|66,69|79,87|90,90|93,93|99,102 Q:3,16|21,21|27,28|30,32|35,55|63,65|70,78|88,89|91,92|94,98|103,112 ??-HHHHHHHHHHTTSS--??S-?---EE?SSS??HHHHHHHHHHHHHSSEEEEEE??-?--?HHH----HHHHHHHHH---------HH-HT-EEEEE----EETTEEEEEE 1LN4|A PF01987.12_AIM24_seed 153 365 !Q:4,5|9,9|16,18|21,21|26,26|29,29|35,38|46,91|96,97|99,99|103,104|110,111|113,113|118,118|125,125|130,135|138,139|151,151|155,159|161,162|164,208|214,216|218,218|227,229|240,241|256,256|262,268|273,341|348,350|353,353|355,355|361,361|364,364 Q:0,3|6,8|10,15|19,20|22,25|27,28|30,34|39,45|92,95|98,98|100,102|105,109|112,112|114,117|119,124|126,129|136,137|140,150|152,154|160,160|163,163|209,213|217,217|219,226|230,239|242,255|257,261|269,272|342,347|351,352|354,354|356,360|362,363 EEEE-?SSS?EEEEEE-?-TT?EEEE?TT?EEEEE----TTEEEEE--???????-------????????????--------??????????EEEE--E?SSS-?EEEEE??S-SSEE-EEEEEG-GGGT------TE--EEEEGGGEEEE-ESS?----B??B???-----??????----------???-----------??--???EEEEE---S-SSEEEEEE---ESSEEEEEEE--EEEEEEEGGGEEEE?SSEEE-------EEEE?-?------------------------------------------------??????-??---????--EEEEEE---EE-E-EEEEE-SS? 1PG6|A PF01989.11_DUF126_seed 60 94 !Q:0,2|6,6|8,8|12,12|15,15|17,18|24,24|26,26|35,36|38,39|42,42|48,48|55,55|57,57|64,64|66,67|79,86|88,90|93,93 Q:3,5|7,7|9,11|13,14|16,16|19,23|25,25|27,34|37,37|40,41|43,47|49,54|56,56|58,63|65,65|68,78|87,87|91,92 ???TTS?B?TTT?BB?S-?SSSTT?B?TTSEEEES??S??SS?TTHHH-HHHHHT?S?SEEEES-S??HHHHHHHHHHT------??E---EE? 2HI6|A PF01990.12_ATP-synt_F_seed 100 140 !Q:5,5|7,7|10,10|19,19|23,52|66,67|82,87|90,91|102,107|110,110|114,115|118,119|122,124|131,132 Q:0,4|6,6|8,9|11,18|20,22|53,65|68,81|88,89|92,101|108,109|111,113|116,117|120,121|125,130|133,139 EEEES?H-HH-HGGGGGGT?EEE???---------------------------SHHHHHHHHHHHH--HTTEEEEEEEHHHH------TT-?HHHHHHTTTS------SS?EEE--EE??SS???SHHHHH--HHHHHHH 2QAI|A PF01991.13_vATP-synt_E_seed 17 222 !Q:90,90|92,92|111,113|121,121|132,132|148,150|155,155|158,178|182,182|190,190|194,195 Q:0,89|91,91|93,110|114,120|122,131|133,147|151,154|156,157|179,181|183,189|191,193|196,221 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?H-HHHHHHHHHHHHHHHHHH?-?SEEEEEE?TTTHHHHTTS-HHHHHHHHHHHTTTS???EEEE?SS??------------------?TTT?SSEEEEE?TTS??EEEEEHHHHHHHHHHHHHHHHHHHHS 4EFA|E PF01992.11_vATP-synt_AC39_seed 10 361 !Q:12,14|25,25|37,38|44,46|51,55|76,77|107,108|112,117|120,121|131,132|142,143|148,148|160,161|163,167|189,195|199,199|224,224|226,228|233,241|244,245|247,247|257,257|263,265|275,295|310,310|318,318|350,351|360,360 Q:0,11|15,24|26,36|39,43|47,50|56,75|78,106|109,111|118,119|122,130|133,141|144,147|149,159|162,162|168,188|196,198|200,223|225,225|229,232|242,243|246,246|248,256|258,262|266,274|296,309|311,317|319,349|352,359 HHHHHHHHHHTT???HHHHHHHHTS?HHHHHHHHHTS--SGGGG???SSHH-----HHHHHHHHHHHHHTTTGGGS??HHHHHHHHHHHHHHHHHHHHHHHHHHTTT??GGG??????SS?-HHHHHHHTT??SHHHHHHHH--HTTT?HHHHHHHHHHH--H?--??HHHHHHHHTHHHHHHHHHHGG-------GSS?HHHHHHHHHHHHHHHHHHHHHTTT-S???GGGT?----????SS??H-HHHHHHHTT?GGGGG???SSTTGGGTT???------------------HHHHHHHHHHHHHH-HHHGGGG?SSSTHHHHHHHHHHHHHHHHHHHHHHHHHHT??STTTSGGG? 3J0J|M PF01993.13_MTD_seed 4 281 !Q:0,0|8,8|10,11|26,27|37,37|40,41|61,62|69,69|71,71|90,90|111,111|120,125|129,130|169,171|176,176|181,181|188,191|221,223|257,259|261,262|264,264|268,268|270,271|273,273|278,280 Q:1,7|9,9|12,25|28,36|38,39|42,60|63,68|70,70|72,89|91,110|112,119|126,128|131,168|172,175|177,180|182,187|192,220|224,256|260,260|263,263|265,267|269,269|272,272|274,277 ?EEEEEEE?S??HHHHHTTGGGSTTS??SSEEEEEEE?TT??SHHHHHHHHHHHHHHHHHH??SEEEEE?S?TTSHHHHHHHHHHHTSSS?EEEEEEGGGGGGHHHHHHTT?EEEEETTS??????TTT??HHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHTT???GGGS?EEEE?GGGGGG????SSHHHHHHHHHHHHHHHHHHHHHHHHHHT???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT???B??B?TTS?B??B?STTS??? 1QV9|A PF01994.11_Trm56_seed 31 144 !Q:1,1|3,6|8,9|11,11|13,13|21,25|49,63|68,72|78,78|81,83|90,90|100,102|122,124|127,127|132,134|138,139|143,143 Q:0,0|2,2|7,7|10,10|12,12|14,20|26,48|64,67|73,77|79,80|84,89|91,99|103,121|125,126|128,131|135,137|140,142 H?S?--?B??B?S?HHHHHHH?---?SEEEEEEEEEEEHHHHHHHHHHH---------------HHTT??---EEEEE?SS???HHHHHH?SEEEESSSS???HHHHHHHHHHHHTTTGGGG???SS?SEEE???SSS??EEE? 2O3A|A PF01995.11_DUF128_seed 36 259 !Q:0,2|14,16|23,23|34,47|66,68|79,79|83,92|99,99|112,113|125,125|128,129|141,141|144,144|153,163|191,195|200,201|204,205|208,209|214,216|226,226|239,241|258,258 Q:3,13|17,22|24,33|48,65|69,78|80,82|93,98|100,111|114,124|126,127|130,140|142,143|145,152|164,190|196,199|202,203|206,207|210,213|217,225|227,238|242,257 ???HHHHHHHHHTT???BTTTTB?EEEEEEEEEE--------------GGGHHHHHHHHHHHHHTT--?SSSSEEEEEE?SSE----------EEEEEE?THHHHHHHHHTT??EEEEEEEEEEE?SS?-EEEEEEEESTT?SS?HHHHSGGG?---------?SSSEEEEEEEEEETTTHHHHHHHHHHH---??TTEE--EE??TT??BTTB???TTEEEEEEE?TTHHHHHHHHTT???EEEEEEEEEEGGGSEE? 3NEK|A PF01996.11_F420_ligase_seed 91 406 !Q:2,8|10,11|13,16|25,38|41,41|56,56|64,100|112,121|125,133|141,171|178,187|191,191|199,199|201,205|211,211|213,238|242,250|254,256|259,261|263,263|280,287|292,297|302,303|307,307|309,312|323,328|330,330|334,335|337,374|391,398|405,405 Q:0,1|9,9|12,12|17,24|39,40|42,55|57,63|101,111|122,124|134,140|172,177|188,190|192,198|200,200|206,210|212,212|239,241|251,253|257,258|262,262|264,279|288,291|298,301|304,306|308,308|313,322|329,329|331,333|336,336|375,390|399,404 EE???????T--T??--HHHHHHHH??----------??TT?EEEEEHHHHHHHTT?EEEGGGS???----------------------------------HHHHHHHHHHT--------??HHH---------HHHHHHT-------------------------------EEEEEE?---------SSS?EEEESSS?E-----EEGGG?B?-------------------------TTS--------?TTE---EE???S?HHHHHHHHHHHHHHHH??----??EEEE------EEEE??SSB?S----BEEEEEEEES------B?SEE--E????-???-??????---------------------??EEEHHHHHHHHHHHHT????????EEEEES? 2G9I|A PF01997.11_Translin_seed 74 378 !Q:24,39|43,44|46,54|58,58|61,61|76,76|84,91|98,106|132,158|162,165|167,169|178,240|267,267|271,305|324,339|344,348 Q:0,23|40,42|45,45|55,57|59,60|62,75|77,83|92,97|107,131|159,161|166,166|170,177|241,266|268,270|306,323|340,343|349,377 HHHHHHHHHHHHHHHHHHHHHHHH----------------HTT??S---------STT-HH-HHHHHHHHHHHHHH-HHHHHHH--------HHHTTS?--------GGGGHHHHHHHHHHHHHHHHHHHHH---------------------------HHS----S???HHHHHHTS???????????????--------------------------------????????????????HHHHHHHHHHHHHHHHHHHHHHHHTT?SSH-----------------------------------HHHHHHHHHHHHHHHHHH----------------TTSS?----HHHHHHHHHHHHHHHHHHHHHHHHHHHHT 3ZC1|A PF02002.12_TFIIE_alpha_seed 7 110 !Q:11,13|27,28|30,30|41,41|58,58|64,74|80,80|86,109 Q:0,10|14,26|29,29|31,40|42,57|59,63|75,79|81,85 THHHHHHHTTS?--STTHHHHHHHHHH??B?HHHHHHTTTS?HHHHHHHHHHHHHHTS?EEEEE??---??????EEEEE?THHHH???????????????????????- 2D1H|A PF02005.11_TRM_seed 10 485 !Q:7,26|29,31|45,52|57,58|60,110|117,117|128,129|132,132|135,135|144,144|159,160|162,163|166,166|184,184|191,193|198,198|205,206|209,210|225,225|233,234|241,241|253,253|256,258|323,343|347,348|351,360|367,368|372,372|378,378|380,380|383,383|397,397|399,403|406,407|422,425|428,429|441,442|444,445|458,459|475,475 Q:0,6|27,28|32,44|53,56|59,59|111,116|118,127|130,131|133,134|136,143|145,158|161,161|164,165|167,183|185,190|194,197|199,204|207,208|211,224|226,232|235,240|242,252|254,255|259,322|344,346|349,350|361,366|369,371|373,377|379,379|381,382|384,396|398,398|404,405|408,421|426,427|430,440|443,443|446,457|460,474|476,484 TTEEEEE???--??--------???-?SS???GGGHHHHHHHHHH--------HHHH??S---------------------------------------------------EEEETT?TTSHHHHHHH--HH-SS?SEEEEEES?HHHHHHHHHHHHTT??S??EE?SSEEEEESSSEEEEEES?HHHHHH---HSTT?EEEEEE??SS??HHHHHHHHHHEEEE-EEEEEEE??HHHHTT-SSHHHHHHHHS-SB???STTHHHHHHHHHHHHHHHHHHTTTEEEEEEEEEEETTEEEEEEEEEESHHHHHHHHTTEEEEEE--------------------?TTT??EE----------EEESSS??STT?EEEEE?S?SB?HHHHHHHHHHHHT-S---??SS--HHHHHHHHHHHHHS--??SS??EEHHHHHHHHT??B??HHHHHHHHHHTT??EEEETTEEEEEEESS?HHHHHHHHB 3AY0|A PF02008.15_zf-CXXC_seed 31 53 !Q:0,4|9,9|11,11|17,18|20,21|30,32|38,41|43,47|52,52 Q:5,8|10,10|12,16|19,19|22,29|33,37|42,42|48,51 ?????BTTB?S?STTTT??S??SSSHHHHH---SGGGT????S??-??GGGS? 2J2S|A PF02011.10_Glyco_hydro_48_seed 7 656 !Q:13,13|17,18|20,20|23,23|25,25|27,27|33,35|65,66|82,83|88,96|100,102|105,107|113,113|121,121|123,128|139,143|145,146|153,153|157,157|162,162|164,170|172,172|179,181|183,183|186,187|191,193|199,199|215,215|217,221|228,228|251,251|275,275|279,280|283,287|291,293|300,301|303,304|306,306|313,319|324,325|333,334|344,344|348,349|374,374|378,378|380,381|393,395|398,399|410,410|412,412|439,440|458,458|461,461|465,466|478,485|488,491|494,494|503,504|526,526|529,530|540,543|551,551|555,555|557,557|561,563|566,566|575,581|583,586|589,590|593,593|596,597|600,600|603,603|609,609|630,631|634,636|655,655 Q:0,12|14,16|19,19|21,22|24,24|26,26|28,32|36,64|67,81|84,87|97,99|103,104|108,112|114,120|122,122|129,138|144,144|147,152|154,156|158,161|163,163|171,171|173,178|182,182|184,185|188,190|194,198|200,214|216,216|222,227|229,250|252,274|276,278|281,282|288,290|294,299|302,302|305,305|307,312|320,323|326,332|335,343|345,347|350,373|375,377|379,379|382,392|396,397|400,409|411,411|413,438|441,457|459,460|462,464|467,477|486,487|492,493|495,502|505,525|527,528|531,539|544,550|552,554|556,556|558,560|564,565|567,574|582,582|587,588|591,592|594,595|598,599|601,602|604,608|610,629|632,633|637,654 HHHHHHHHHHHHT?GGG??B?TT-S?B?SBSSS???SSSSSTTEEEHHHHHHHHHHHHHHHHHHS??HHHHHHHHHHHHHTS??TTTS?---?????TTS???EE???SSGGG?SEEEESS-S??????SHHHHHHHHS?????S??SEEETT?SSS?TTTT?S-------S?SSEEEE???S?TT??GGG???EESEE?SSSBBTTBTHHHHEE?S-????EEEEEE?HHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHGGGGGB?TTS??TT--???TTS???SSGGGB??S??S?EEEEEE???--??EEEE??SEEEGGG??HHHHHHHHH?TTS??SSSSHHHHHHHHHHHHHHHHHHTB?SSS?B??EEESSBTTTTB???TT??EETTEEEESS?S?BTTBTTSBTHHHHHHHHHHHHHHHHH??HHHHHHHHHHHHHHHHH?EE?TTS-?EEEEEEEEEES?????--?SS????TT?EEEEEEEE??HHHHHHHHHHHHHHHHHHHHH-SS??HHHHHHHHH----HHHHHHH-HSB?S-SSB???EE?GGGGHHHH?------B????TT??EE?TT??EE?TT?BTGGG?GGGGGSTTHHHHHHHHHHTS??EE???BHHHHHHHHHHHHHHHHH? 4EL8|A PF02012.15_BNR_seed 188 12 !Q:9,9 Q:0,8|10,11 EEESSTTSS?EE 2VK6|A PF02013.11_CBM_10_seed 92 45 !Q:0,3|10,12|15,15|17,17|22,23|39,39|45,45 Q:4,9|13,14|16,16|18,21|24,38|40,44 ?--?GGGGTT--?EE?S?GGGS-?EEEEETTEEEEEETT-EEEEE- 2J4N|A PF02014.11_Reeler_seed 40 179 !Q:0,2|6,10|12,15|20,21|23,26|28,28|37,38|41,42|45,45|52,55|58,58|61,62|64,64|76,106|111,111|113,114|121,121|125,128|131,131|135,137|140,140|142,142|149,149|153,154|158,161|173,173|177,177 Q:3,5|11,11|16,19|22,22|27,27|29,36|39,40|43,44|46,51|56,57|59,60|63,63|65,75|107,110|112,112|115,120|122,124|129,130|132,134|138,139|141,141|143,148|150,152|155,157|162,172|174,176|178,178 ???STT----?S----SEEE??B----B?SEEEEETT??SB??TT?EEEEEE----EE?TT??B-SEEEEEEEETT??????---------------------????SEEE?S-?TTTEEE?SSS----TT?EEE---SS?S?BSEEEE-EEE??STT?-??EEEEEEEESSS?EEE?S 2ZOT|A PF02015.11_Glyco_hydro_45_seed 6 216 !Q:7,9|11,12|19,20|27,30|32,32|36,36|38,38|40,44|47,48|55,56|59,60|65,65|67,68|83,83|86,87|94,94|101,101|103,106|112,112|121,128|134,134|138,139|143,145|152,156|164,165|174,174|186,186|192,193|195,195|203,205|213,215 Q:0,6|10,10|13,18|21,26|31,31|33,35|37,37|39,39|45,46|49,54|57,58|61,64|66,66|69,82|84,85|88,93|95,100|102,102|107,111|113,120|129,133|135,137|140,142|146,151|157,163|166,173|175,185|187,191|194,194|196,202|206,212 EEEEEEE???B??GGGSTT--SSSBSS????B?TTS?B?S?----TT??BTTSTT??BB??TTSS?E--EEETTEEEEEEEEE?TT??HHHHTT?EEEEEE?S----GGGTT?EEEEEEEE????????EEEEE?TTS??TTT?-?HHHHHS---??SSBTTTB??SGGGGGGS?GGGHHHHHHTT-TTTTT??S?EEEEEEE???HHHHHHH??? 1OA7|A PF02016.10_Peptidase_S66_seed 167 462 !Q:4,4|8,9|14,14|16,16|18,19|22,23|32,32|36,36|41,41|46,50|52,56|59,61|63,64|78,78|83,84|90,92|94,94|102,106|109,113|116,118|122,133|138,138|153,154|156,156|158,159|162,169|175,184|186,201|203,203|214,216|219,220|222,222|226,228|230,237|241,243|247,247|251,253|256,259|264,264|266,275|290,302|311,311|313,335|338,344|351,352|379,380|386,388|391,399|401,403|414,414|416,417|422,426|428,428|435,435|440,440|442,449|454,454|459,460 Q:0,3|5,7|10,13|15,15|17,17|20,21|24,31|33,35|37,40|42,45|51,51|57,58|62,62|65,77|79,82|85,89|93,93|95,101|107,108|114,115|119,121|134,137|139,152|155,155|157,157|160,161|170,174|185,185|202,202|204,213|217,218|221,221|223,225|229,229|238,240|244,246|248,250|254,255|260,263|265,265|276,289|303,310|312,312|336,337|345,350|353,378|381,385|389,390|400,400|404,413|415,415|418,421|427,427|429,434|436,439|441,441|450,453|455,458|461,461 EEEE?SSS-?GGGS?H-H--HH--HHHHHHHH-HTT?EEEE?TTTT??--?T-----TS---S??HHHHHHHHHHHHH?TTEE--EEEES???S?GGGGGGG??---HH-----HH---HTS--------??--EEEE?GGGHHHHHHHHHHH-?B?E--EE???-----GGGGG?--------?S----------------S?HHHHHHHHHH---HH??S?EEE???S--------EEB???TTT?SSS???EE????EEEE?E----------EEEEEEEEEEHHHH-------------GGGTTSTT-S?--------------------??TT-------EEEEEE??STTGGGHHHHHHHHHHHHHTSTTGGG??EEEEE???GG---------G???HHHHHHHHHT?G--GGTT-----S?EEEEES?SSSB-S??-----?EEET?EEEE--E 4E94|A PF02017.10_CIDE-N_seed 7 80 !Q:1,4|6,6|8,8|11,12|15,19|35,35|37,37|41,42|50,51|53,53|63,63|66,66|72,72|75,79 Q:0,0|5,5|7,7|9,10|13,14|20,34|36,36|38,40|43,49|52,52|54,62|64,65|67,71|73,74 S????B?B?SS??SB?????SSHHHHHHHHHHHHT?S?TTS??EEEETTT??B?SSHHHHHHS?SS?BEEEE?SS????? 2EEL|A PF02018.12_CBM_4_9_seed 47 206 !Q:3,3|5,5|8,8|11,28|30,31|34,34|39,39|42,48|58,58|61,62|65,65|76,76|79,82|93,94|98,98|101,101|114,122|135,143|145,146|153,154|156,157|172,172|175,178|180,181|191,192|196,203 Q:0,2|4,4|6,7|9,10|29,29|32,33|35,38|40,41|49,57|59,60|63,64|66,75|77,78|83,92|95,97|99,100|102,113|123,134|144,144|147,152|155,155|158,171|173,174|179,179|182,190|193,195|204,205 GBS?S?SS?TT------------------S??TT?EEEE?TT-------EEEEEEEEE?TT-?TT?EEEEEEEEEE?SS----GGGEEEEEEE--EEE?TT?EEEEEEEEEESS?--------EEEEEEEEESST---------T??EEESST--T??EEEBTTEEEEEEEE-EE??--S??EEEEEEEEE??GGG------??SS 1DYO|A PF02019.13_WIF_seed 10 151 !Q:3,3|12,17|20,22|30,32|38,42|46,47|54,54|57,58|66,67|70,71|82,83|87,87|89,90|95,95|101,101|104,104|111,112|114,116|118,118|131,131|134,137|139,139|144,145|148,148 Q:0,2|4,11|18,19|23,29|33,37|43,45|48,53|55,56|59,65|68,69|72,81|84,86|88,88|91,94|96,100|102,103|105,110|113,113|117,117|119,130|132,133|138,138|140,143|146,147|149,150 EEE?HHHHHHHH------SS???EEEESTT???SHHHH-----HHS??SSSSEE?TT??EEEEEEE??TT??EEEEEEEEEE??SSS?B??EESS?SEEEE?SS?EEEEEE??B???S?EEEEEEEEEEEE?TT----S?EEEE??TT?EE 2YGN|A PF02020.13_W2_seed 77 116 !Q:14,16|18,18|22,32|38,39|42,42|44,48|57,57|63,63|74,77|81,82|89,90|93,93|103,103|106,106|109,115 Q:0,13|17,17|19,21|33,37|40,41|43,43|49,56|58,62|64,73|78,80|83,88|91,92|94,102|104,105|107,108 HHHHHHHHHHHHHH---H-HHT-----------HHHHG--GG-H-----HHHHHHHH-HTTSS?HHHHHHHHHS-???SSS-?HHHHHH--HH-HHHHHHHHH-HH?SS??????? 3JUI|A PF02021.12_UPF0102_seed 8 99 !Q:0,0|14,14|24,24|36,37|49,63|81,81|83,83|98,98 Q:1,13|15,23|25,35|38,48|64,80|82,82|84,97 ?HHHHHHHHHHHTT?EEEEEEEEE-TTEEEEEEEEE--TTEEEEEEEEE?--??????-?????HHHHHHHHHHHHHHHHH?G-GGTTSEEEEEEEEE? 3FOV|A PF02022.14_Integrase_Zn_seed 92 40 !Q:1,3|10,10|20,21|37,38 Q:0,0|4,9|11,19|22,36|39,39 H???SSHHHH?HHHHHHHHT??HHHHHHHHHHSHHHH??S 3F9K|A PF02023.12_SCAN_seed 62 103 !Q:0,0|12,13|15,15|17,21|39,41|44,45|63,63|74,77|91,92|94,102 Q:1,11|14,14|16,16|22,38|42,43|46,62|64,73|78,90|93,93 ?STTHHHHHHHT??S?S---??SSHHHHHHHHHHHHHHH??-SS??HHHHHHHHHHHHHHHHS?THHHHHHHTS????HHHHHHHHHHHHT??S??-?----- 4E6S|A PF02024.10_Leptin_seed 7 146 !Q:0,2|23,39|41,43|46,47|68,69|95,103|105,105|114,114|119,119|142,146 Q:3,22|40,40|44,45|48,67|70,94|104,104|106,113|115,118|120,141 ???HHHHHHHHHHHHHHHHHHHH?????????????????S???SS??SSHHHHHHHHHHHHHHHHTS??HHHHHHHHHHHHHHHHHHHHHHHTT?????????S?GGGGHHHH?BTTB?HHHHHHHHHHHHHHHHHHHGGG????- 1AX8|A PF02025.10_IL5_seed 6 113 !Q:0,5|25,26|29,29|31,34|38,38|58,60|109,112 Q:6,24|27,28|30,30|35,37|39,57|61,108 ??????TTHHHHHHHHHHHHHHHHH??TT?B????SSS?HHHHHHHHHHHHHHHHHHS???HHHHHHHHHHHHHHHHHHHHHHTTSSEEEEHHHHHHHHHHHHHHHHHH???? 3B5K|A PF02026.11_RyR_seed 38 132 !Q:0,8|11,14|19,36|56,71|75,75|77,78|81,83|90,90|93,93|95,95|100,100|123,123|128,128|130,130 Q:9,10|15,18|37,55|72,74|76,76|79,80|84,89|91,92|94,94|96,99|101,122|124,127|129,129|131,131 ?????????TT????GGGH------------------HHHHHHHHHHHHHHHHHHH----------------HTT?B??SS?--BTTTTB?TT?S?GGGS?HHHHHHHHHHHHHHHHHHHHTT?EEEE?S-S 4ETV|A PF02027.12_RolB_RolC_seed 41 256 !Q:0,1|5,7|9,9|11,11|14,15|19,19|37,37|42,42|45,45|50,81|85,85|87,87|91,91|94,95|101,101|111,111|117,118|130,130|135,135|137,142|153,154|160,160|164,164|175,177|194,198|208,235|241,248|254,255 Q:2,4|8,8|10,10|12,13|16,18|20,36|38,41|43,44|46,49|82,84|86,86|88,90|92,93|96,100|102,110|112,116|119,129|131,134|136,136|143,152|155,159|161,163|165,174|178,193|199,207|236,240|249,253 ??GGG???E-E?TT??BHH-HHHHHHHHHHHHHHHHH?SEEE?SB?SSST--------------------------------TSB?S?EEE?SS??EEEEE?HHHHHHHHH-HTEEE??BTTTBEEEESS?TTSS?H------HHHHHHHHHH??SSSSS?GGG?GGGGSEEEEE-??BTTEEEEEEEEETTEE-----EEEEEESTT???????????---??????????????SSEEE??-?---?EEEES?? 3AQ3|A PF02028.12_BCCT_seed 145 722 !Q:17,21|24,24|66,66|70,71|73,73|78,80|83,83|96,97|115,134|138,149|152,152|154,154|174,174|188,188|190,208|216,216|221,222|224,224|227,229|232,235|272,295|298,298|318,319|321,322|347,348|368,379|385,389|392,394|397,402|405,405|407,452|485,486|515,523|528,532|535,555|558,558|560,560|572,584|591,594|625,628|630,631|633,634|652,652|657,658|662,665|694,714|721,721 Q:0,16|22,23|25,65|67,69|72,72|74,77|81,82|84,95|98,114|135,137|150,151|153,153|155,173|175,187|189,189|209,215|217,220|223,223|225,226|230,231|236,271|296,297|299,317|320,320|323,346|349,367|380,384|390,391|395,396|403,404|406,406|453,484|487,514|524,527|533,534|556,557|559,559|561,571|585,590|595,624|629,629|632,632|635,651|653,656|659,661|666,693|715,720 HHHHHHHHHHHHHHHHH-----SS-SHHHHHHHHHTTHHHHHHTHHHHHHHHHHHHHHHHHHHHSG-GGG??S-SSTT???SS?HHHHHHHHHHHH??HHHHHHHHHHHHHHHHT?----------------?--TTS?-----------SS?H-HHHHHHHHHHHSHHHHHHH-HHHHHHHHHHTTT-S???----------------SSGGGGG-TTTS?-T-TT-??SS----SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTS-?-------?--??-?------??HH-HHHHHHHHHHHTTGGGTTS??S--HHHHHHHHHHHHHHHHHHHHHHHS?-HHHHHHHHHHHHHHHHHHH------------HHHHT??---TT---TT------SS?H----------------------------------------------HHHHHTTHHHHHHHHHTTHHHHHHHHHHHTTT??HHHHHHHHHHHHHHHHHHHHHHHHHHHH---------HHHH-----HT?--????--------------TT?S-HHHHHHHHHTS-------------TTHHHH----HHHHHHHHHHHHHHHHHHHHHHHHHHTTTT---?S--S??HHHHHHHHHHHHHHHHH-HHHH--HGG----GHHHHHHHHHHHHHHHHHHHHHHHHHHH---------------------HHHHHT? 2WSW|A PF02031.11_Peptidase_M7_seed 4 133 !Q:0,0|10,10|28,28|36,36|39,40|48,49|52,53|58,58|62,62|76,76|91,94|98,98|101,101|109,109|112,115|117,118|132,132 Q:1,9|11,27|29,35|37,38|41,47|50,51|54,57|59,61|63,75|77,90|95,97|99,100|102,108|110,111|116,116|119,131 ?EEEEEEEEE?GGGHHHHHHHHHHHHHH?SSEEEEE?SS-?SEEEEEE??TT??EEEE?SSS?EEEEEEHHHHHHS?HHHHHHHHHHHHHT????TTS?TT?GGGTTTT?TT????S??HHHHHHHHHHTTT? 4HX3|A PF02033.13_RBFA_seed 183 182 !Q:0,0|6,8|21,22|25,30|34,44|53,53|57,57|64,66|69,72|74,96|98,98|100,119|123,124|147,150|153,154|161,181 Q:1,5|9,20|23,24|31,33|45,52|54,56|58,63|67,68|73,73|97,97|99,99|120,122|125,146|151,152|155,160 ?HHHHH---HHHHHHHHHHHH--HH-??--?TTT---------??EEEEEEEE?TTS?EEEEEE---EE----S---------------------??S?H--------------------HHH--HHHHHHHHHTHHHHHHHHHHHH?--?SS??EEEEEE?---?----???????????? 1JOS|A PF02035.10_Coagulin_seed 2 174 !Q:1,5|8,9|14,15|18,20|39,39|58,60|65,66|78,81|85,86|91,94|102,103|108,109|116,116|118,120|126,126|130,130|132,132|136,136|139,140|168,168|172,173 Q:0,0|6,7|10,13|16,17|21,38|40,57|61,64|67,77|82,84|87,90|95,101|104,107|110,115|117,117|121,125|127,129|131,131|133,135|137,138|141,167|169,171 S?????TT??TTTS??SS???HHHHHHHHHHHHHHHHTT?SSTTSGGGTTTSHHHHHH???BTTT??GGGGSGGGSTT????SSB??EEEE????SEEEBTT??EEEE??BTTTTB?B???EEEET-TSS?B?SSS?EE??EEEEEEEEEEETTTTEEEEEEEEEEEE?BEE?? 1AOC|A PF02036.12_SCP2_seed 174 141 !Q:8,13|16,16|26,26|28,34|41,42|44,44|48,50|52,52|59,61|64,64|66,66|69,76|80,85|87,88|93,94|106,108|110,112|119,125|127,127|135,135|140,140 Q:0,7|14,15|17,25|27,27|35,40|43,43|45,47|51,51|53,58|62,63|65,65|67,68|77,79|86,86|89,92|95,105|109,109|113,118|126,126|128,134|136,139 HHHHHHHH------HH-HTHHHHHHH?E-------EEEEEB-?S?TTS?-?B?EEEEES---ST-T?EE--------EET??-???S--EEEE??HHHHHHHHHTS---S???SSTTTT?--????S-SSSTTTS?SGGG? 4AXH|A PF02037.22_SAP_seed 182 37 !Q:4,4|17,20|22,24 Q:0,3|5,16|21,21|25,36 TTTS?HHHHHHHHHHTT????S?--HHHHHHHHHHHH 1JJR|A PF02038.11_ATP1G1_PLM_MAT8_seed 23 55 !Q:4,5|10,10|37,38|44,44|47,47|54,54 Q:0,3|6,9|11,36|39,43|45,46|48,53 HHHH--SGGG?STHHHHHHHHHHHHHHHHHHHHHHHH--HHHHH-HH?TTTSSS? 2JO1|A PF02041.11_Auxin_BP_seed 4 170 !Q:0,9|18,19|21,21|24,24|34,34|39,40|51,51|54,54|56,57|64,64|72,73|79,81|87,88|90,90|96,96|104,104|107,108|113,115|119,119|131,132|142,142|146,146|152,152|163,169 Q:10,17|20,20|22,23|25,33|35,38|41,50|52,53|55,55|58,63|65,71|74,78|82,86|89,89|91,95|97,103|105,106|109,112|116,118|120,130|133,141|143,145|147,151|153,162 ---???????SEEEGGGS??B?TT?TTEEEEEEE?HHHH??SSEEEEEEEE?TT?B??EEEESS?EEEEEEE??EEEEE?-?SSSSS??S?EEEEE?TTEEEEE?TT??EEEE???SSS?EEEEEEEESSS??EEEESSTTS?GGG?EEESS?TTTHHHHHHT??---?? 1LR5|A PF02043.12_Bac_chlorC_seed 12 84 !Q:0,0|53,58|63,83 Q:1,52|59,62 ?SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHTGGGTTTHHHHHHHTTTTIIII------ISTT?-------------------- 2K37|A PF02045.10_CBFB_NFYA_seed 25 80 !Q:0,2|4,6|26,28|32,52|56,57|59,59|61,61|72,72|74,74|78,78 Q:3,3|7,25|29,31|53,55|58,58|60,60|62,71|73,73|75,77|79,79 ???S???TTTHHHHHHHHHHHHHHHH---HTT-------------------??SSS??S?S?HHHHHHHHHS?B?TTS?B 4G92|A PF02046.10_COX6A_seed 31 178 !Q:0,60|62,84|87,91|101,105|112,112|122,122|124,125|127,127|129,148|153,154|157,158|166,166|169,170|174,175 Q:61,61|85,86|92,100|106,111|113,121|123,123|126,126|128,128|149,152|155,156|159,165|167,168|171,173|176,177 ???---------------???---------????????----------------------?S??-------?------------?SS?---?HHHHHHHHH-----HTHHHH-HHHHHHHHT-T--S?S??----------????????TTSS??SS??SSTTSSS?TT??TTT??BT 1V55|G PF02050.11_FliJ_seed 147 130 !Q:9,11|34,35|39,44|46,46|125,129 Q:0,8|12,33|36,38|45,45|47,124 HHHHHHHHH---HHHHHHHHHHHHHHHHHHHHHH--HHT??????S-GGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT????? 3AJW|A PF02055.11_Glyco_hydro_30_seed 3 502 !Q:0,0|2,4|8,8|18,18|21,23|25,32|46,47|59,62|77,78|84,85|96,96|114,116|124,125|131,133|135,136|140,140|143,143|146,149|167,167|170,171|179,181|188,188|194,194|199,199|224,226|232,232|243,244|247,248|250,251|273,273|305,306|317,319|331,331|343,346|350,350|352,353|356,356|384,384|386,386|390,392|395,400|414,414|427,428|431,431|441,443|445,445|452,452|456,456|464,464|468,468|471,473|483,485|492,492 Q:1,1|5,7|9,17|19,20|24,24|33,45|48,58|63,76|79,83|86,95|97,113|117,123|126,130|134,134|137,139|141,142|144,145|150,166|168,169|172,178|182,187|189,193|195,198|200,223|227,231|233,242|245,246|249,249|252,272|274,304|307,316|320,330|332,342|347,349|351,351|354,355|357,383|385,385|387,389|393,394|401,413|415,426|429,430|432,440|444,444|446,451|453,455|457,463|465,467|469,470|474,482|486,491|493,501 ?B???EEE?SSSSEEEEE?SS???B????????TTEEEEEEEETTS??SEEEEEEEESS????SEEEEEEEEEEEEE??EEEEE??HHHHHHHTTS?HHHHHHHHHHHHSTTTT???EEEEEES??SSSSS???S??SSS?TT?TT????HHHHHTHHHHHHHHHHH?SS??EEEEEES???GGGBTT?SSSSS?BBSS?TTSHHHHHHHHHHHHHHHHHHHTT???SEEES?SSGGGGGSTT??SS??B??HHHHHHHHHHTHHHHHHTSTT-TTSEEEEEEEEGGGTTHHHHHHHTSHHHHTT??EEEEEEETTS???HHHHHHHHHHH?TTSEEEEEEEE????TTS?S??TT?HHHHHHHHHHHHHHHHTTEEEEEEEES?B?TTS???SS??????SEEEEGGGTEEEE?HHHHHHHHHHTT??TT?EEEEEEESS??-S?EEEEEE?TTS?EEEEEEE?SSS?EE---EEEEETTTE---EEEEEE?TTEEEEEEE 2NSX|A PF02056.11_Glyco_hydro_4_seed 8 189 !Q:5,5|26,26|34,34|36,36|38,39|57,57|67,67|75,75|81,83|86,89|106,111|140,140|143,143|148,149|151,151|166,167|171,172|188,188 Q:0,4|6,25|27,33|35,35|37,37|40,56|58,66|68,74|76,80|84,85|90,105|112,139|141,142|144,147|150,150|152,165|168,170|173,187 EEEEE?TTSSSHHHHHHHHHHTTTTS?EEEEEEE?S?H--HHHHHHHHHHHHHHHHH?TTSEEEEES?HHHHHSS?SEEEE???TT----HHHHHHHHHHHHHTTT???--?SSSHHHHHHHHHHHHHHHHHHHHHHHHH?TT?EEEE??S?HHHHHHHHHHHSTT??EEE??SHHHHHHHHHHHHHT? 3U95|A PF02057.10_Glyco_hydro_59_seed 3 669 !Q:0,24|29,30|33,33|38,39|46,46|49,49|57,58|77,78|86,87|91,91|96,98|100,100|105,107|109,110|124,124|127,127|135,135|137,137|146,146|170,174|177,177|179,179|183,185|201,201|204,204|212,212|223,223|230,231|238,238|241,243|251,251|260,260|262,262|283,285|291,291|295,295|297,297|305,305|310,312|316,318|320,321|334,335|338,338|343,344|347,347|351,351|358,358|362,362|369,371|375,377|381,389|397,397|403,404|413,419|430,430|435,435|442,442|452,468|470,470|476,479|482,482|487,487|490,490|496,496|502,502|505,505|507,507|516,518|520,521|523,523|526,528|537,537|540,541|552,552|557,557|566,568|575,575|596,597|605,605|607,608|611,611|639,640|643,645|655,656|668,668 Q:25,28|31,32|34,37|40,45|47,48|50,56|59,76|79,85|88,90|92,95|99,99|101,104|108,108|111,123|125,126|128,134|136,136|138,145|147,169|175,176|178,178|180,182|186,200|202,203|205,211|213,222|224,229|232,237|239,240|244,250|252,259|261,261|263,282|286,290|292,294|296,296|298,304|306,309|313,315|319,319|322,333|336,337|339,342|345,346|348,350|352,357|359,361|363,368|372,374|378,380|390,396|398,402|405,412|420,429|431,434|436,441|443,451|469,469|471,475|480,481|483,486|488,489|491,495|497,501|503,504|506,506|508,515|519,519|522,522|524,525|529,536|538,539|542,551|553,556|558,565|569,574|576,595|598,604|606,606|609,610|612,638|641,642|646,654|657,667 ???????????------------??EEEE??TT?EEEE??EEEEEE?SS?TTTTTTT??TTHHHHHHHHHHSTTTSS??SEEEEEE??SSB?SSSB???S?SSTT???S??SSHHHHHHHHHHH?TT?EEEEEES?B?GGGGTTSS?TTSSHHHHHHHHHHHHHHHHHHH?????EE?S?TTS???HHHHHHHHHHHHHTT?TT?EEEEEEE?STTHHHHHHH?HHHHHH??EEEEES?TT???HHHHHHT?EEEEEEEE?S?TTHHHHHHHHHHHHHHHHHH???EEEEE?SEE?S?TTSTTTT?SSEE???TTT???B??HHHHHHHHHHTT??TT?EEES??EE?TTS?EEEEEE?SSS?EEEEEE???STT???SSS?????????EEEEEEE?GGGTT??EEEEEEEE???????EEEEEEEEEE?TTTT?EEEEEE?TTEEEEEES?????????????????S?SEEEE????SS?SSSS?TT?EEEES?EEEEE?TT?S-TTSEEEEE???S??B?SS???SSEEEEES?TT??EEEEEEEEEE?STTT?EEEEEEEE???GGGGGG?EEEEEEEETTTEEEEEEETT??SEEEEEE?S??TT?EEEEEEEEETTEEEEEETTEEEEEEEE??SS???EEEEEESSS??EEEEEEEEEEE? 3ZR5|A PF02058.10_Guanylin_seed 15 103 !Q:0,2|12,12|22,23|25,30|32,36|39,39|42,45|47,52|55,56|62,62|87,88|101,102 Q:3,11|13,21|24,24|31,31|37,38|40,41|46,46|53,54|57,61|63,86|89,100 --?EEESSSSEE?SHHHHTTTT??S------S?????SS?TT????S??????SS?-SSTTS?GGGHHHHTSTTHHHHHHHHHHHHT??TTTTTTSSTTEE?? 1O8R|A PF02059.10_IL3_seed 5 121 !Q:0,7|9,9|15,16|28,38|41,43|45,45|50,50|69,69|75,76|88,92|95,101|103,103|106,107 Q:8,8|10,14|17,27|39,40|44,44|46,49|51,68|70,74|77,87|93,94|102,102|104,105|108,120 ------??S?SSSSS??HHHHHHHHHHS?-------???SS???S?SGGG?TTTHHHHHHHHHHHHTTT?GGGGS??HHHHHHHHHHS?????SS???????S?HH--HHHHHHHHHHHHT 1JLI|A PF02060.10_ISK_Channel_seed 3 130 !Q:0,0|9,9|23,24|29,29|34,34|36,37|40,40|45,45|72,76|83,83|87,88|90,91|109,109|112,113|117,129 Q:1,8|10,22|25,28|30,33|35,35|38,39|41,44|46,71|77,82|84,86|89,89|92,108|110,111|114,116 ?TTHHHHHH?TTHHHHHHHHHHT??TTSS-GGGS?S??TT?SSTT?HHHHHHHHHHHHHHHHHHHHHHHHHH?????TTTTTS?TTT??S??HHHHHHHHHHHHHHTTS?SS??SSS????????????? 2K21|A PF02064.10_MAS20_seed 33 149 !Q:0,40|43,65|67,67|69,69|72,75|86,87|100,100|110,110|118,118|121,124|135,136|147,147 Q:41,42|66,66|68,68|70,71|76,85|88,99|101,109|111,117|119,120|125,134|137,146|148,148 --???-?----------------------------------SS-----------------------S?S-SS----HHHHHHHHHH--HHHHHHHHHHHT?HHHHHHHHH-HHHHHHS?HH----HHHHHHHHHS??HHHHHHHHHS?S 2V1T|A PF02065.13_Melibiase_seed 13 456 !Q:3,5|29,32|35,36|43,46|50,50|57,59|71,75|80,81|86,86|88,88|93,96|102,102|105,106|109,109|113,113|117,119|128,135|140,140|147,147|152,153|162,162|167,170|174,176|185,185|208,209|214,220|222,224|228,228|234,234|255,255|263,263|270,270|283,283|286,288|302,313|316,316|326,326|329,329|333,338|349,349|357,357|361,362|385,389|398,398|401,402|405,405|414,414|427,430|433,444|448,450|453,453 Q:0,2|6,28|33,34|37,42|47,49|51,56|60,70|76,79|82,85|87,87|89,92|97,101|103,104|107,108|110,112|114,116|120,127|136,139|141,146|148,151|154,161|163,166|171,173|177,184|186,207|210,213|221,221|225,227|229,233|235,254|256,262|264,269|271,282|284,285|289,301|314,315|317,325|327,328|330,332|339,348|350,356|358,360|363,384|390,397|399,400|403,404|406,413|415,426|431,432|445,447|451,452|454,455 EEE???EEEEEESBHHHHHHHHHHHHHHH----HT??STTSSS????EEE?HHHHTT???HHHHHHHHHHH-----HHHT??EEEE?S?SBTT---?SSTTS?TT??SB?TTT?TTH---HHHHHHHH--------HTTT?EEEEEE?TTEE?-SSSHHHHH?TTSB??-?TTS???BBTTBEEB?TTSHHHHHHHHHHHHHHHTTTT??EEEE???????S???TTS?GGGGG-GHHHHHHHHHHHHHHHHHHH?TTSEEEE?BTBBTT?SHHHHHHSSEEE?BS???HHHHHHHHHHHTT------------TS?GGGEEEEEE?SS?SSS????-?HHHHHHHHTT-SEEEEES?GGG??HHHHHHHHHHHHHHHHHHHHHH-----HSEEEEEE?TT--TS-SEEEEEEE?TTSSEEEEEEEE????TT??---------?EEE???SS?TT 3A5V|A PF02068.11_Metallothio_PEC_seed 4 81 !Q:0,34|36,36|42,43|47,48|51,59|64,64|66,70|73,75|80,80 Q:35,35|37,41|44,46|49,50|60,63|65,65|71,72|76,79 ----------------------?----------??S?BTTTB??TTS??TT??-??????SSSS?S?????SS???HHHH? 2L62|A PF02069.11_Metallothio_Pro_seed 13 57 !Q:0,4|6,7|12,15|17,17|27,27|39,39|42,49|54,56 Q:5,5|8,11|16,16|18,26|28,38|40,41|50,53 ?????B??SSTT????B?TTTSEESSS?EESSHHHHHTS?SS????----SSTT??? 1JJD|A PF02072.10_Orexin_seed 3 131 !Q:0,35|37,38|56,56|65,130 Q:36,36|39,55|57,64 ---------------------------------???S??TTTSSSTHHHHHHHHTS?HHHHHHHT?----------------------------------------------------------------- 1CQ0|A PF02073.10_Peptidase_M29_seed 73 456 !Q:2,3|18,22|27,29|32,32|40,40|43,43|60,60|69,75|86,86|88,88|92,93|96,97|99,100|115,115|122,125|133,133|145,145|149,149|163,163|169,171|179,179|182,182|206,206|230,231|238,238|241,245|253,254|258,259|261,261|263,263|266,266|268,268|271,271|274,274|279,281|285,287|290,290|297,298|300,300|311,311|325,327|353,354|364,366|375,379|382,382|388,390|400,401|408,408|411,414|416,416|422,432|435,435|441,441|444,445 Q:0,1|4,17|23,26|30,31|33,39|41,42|44,59|61,68|76,85|87,87|89,91|94,95|98,98|101,114|116,121|126,132|134,144|146,148|150,162|164,168|172,178|180,181|183,205|207,229|232,237|239,240|246,252|255,257|260,260|262,262|264,265|267,267|269,270|272,273|275,278|282,284|288,289|291,296|299,299|301,310|312,324|328,352|355,363|367,374|380,381|383,387|391,399|402,407|409,410|415,415|417,421|433,434|436,440|442,443|446,455 SS--SHHHHHHHHHHHHH-----HTTT???TT?EEEEEEE-GG-GHHHHHHHHHHHHHTT?SEEEEEEE------?HHHHHHHHHH-S?HHH--HS--S??HHHHHHHHHHHHTT?EEEEEE?-??TTTTTTS?HHHHHHHHHHH-HHH-THHHHHHHHTTSS?EEEEE???HHHHHHH?TT?SSHHHHHHHHHHHHHHHTTTTSS-SHHHHHHHHHHHHHHHHHHHHHH??SEEEEE-ET-----TEEEEEE??TTB??B?S?EE?T-TS?EE?SEES???EEE???TT?EEEEEE??S?EEETTEEEBS?EEEEETTEEEEEE?--SBSHHHHHHHHHSSTTTTSEEEEEE??TTSHHHHTT???SSHHHHTT-----SS?EEEEE???GGGBTTGGG??HHHHHH-TT????S?EEEEE??--------?TT?EEEEE?TT??EEEEEETTEE 2AYI|A PF02074.10_Peptidase_M32_seed 3 508 !Q:0,4|34,35|59,59|73,74|79,79|100,100|126,126|144,146|152,154|157,157|159,163|175,176|204,207|213,216|233,234|238,240|244,244|247,248|262,264|267,267|289,289|300,300|302,302|342,343|353,357|359,359|363,364|386,386|388,388|406,408|418,418|425,425|428,428|450,450|461,462|481,481|494,495 Q:5,33|36,58|60,72|75,78|80,99|101,125|127,143|147,151|155,156|158,158|164,174|177,203|208,212|217,232|235,237|241,243|245,246|249,261|265,266|268,288|290,299|301,301|303,341|344,352|358,358|360,362|365,385|387,387|389,405|409,417|419,424|426,427|429,449|451,460|463,480|482,493|496,507 ?????HHHHHHHHHHHHHHHHHHHHHHHHHHTTT??TTSHHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHT--GGGS?HHHHHHHHHHHHHHHHHTTS?HHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHH---HHHHH?-?SS?T-----THHHHHHHSTT??HHHHHHHHHHHHHHHHHHHHHHHSSTT????TTTSS-???HHHHHHHHHHHHHHTT??TTS-??EEE?SS??EEEEETTEEEEEE???TT?THHHHHHHHHHHHHHHHHTTS?GGGTTSSSSS?S?HHHHHHHHHHHHTTTTTSGGGGTTTHHHHHHHSTTTTTT??HHHHHHHHT?????S?GGG??TTTHHHHHHHHHHHHHHHHTT?S?GGGHHHHHHHHHHHHHS???SSTTTTTTS?STTTTT?TT?THHHHHHHHHHHHHHHHHHHH?TTHHHHHHHT??HHHHHHHHHHTTTTTTSS?HHHHHHHHHSSS??HHHHHHHHHHHH 1K9X|A PF02075.12_RuvC_seed 9 152 !Q:5,6|18,18|33,35|37,38|58,59|67,72|95,96|115,116|130,134|136,138|140,140 Q:0,4|7,17|19,32|36,36|39,57|60,66|73,94|97,114|117,129|135,135|139,139|141,151 EEEEE??SSEEEEEEEEE-ETTEEEEEEEEEEE???S-?HHHHHHHHHHHHHHHHHHH??SEEEEEE??????TTTHHHHHHHHHHHHHHHHTTT??EEEEEHHHHHHHHTSSSS??HHHHHHHHHHHTT?????S---S?THHHHHHHHHH 4EP4|A PF02078.11_Synapsin_seed 4 105 !Q:0,4|12,13|17,17|25,25|39,39|52,52|61,61|65,65|71,72|78,78|80,80|82,83|88,90|102,103 Q:5,11|14,16|18,24|26,38|40,51|53,60|62,64|66,70|73,77|79,79|81,81|84,87|91,101|104,104 ----?EEEEEEE??TTS?HHHHHTT?EETTTEEEEEEEE?GGGEEEEEETTS?EEEEEEES?SSS?EEEEE??SEEEE?S?S??SSTT???HHHHHHHHHTT??E 1PK8|A PF02080.16_TrkA_C_seed 181 99 !Q:5,6|8,8|10,10|12,12|16,17|22,22|24,30|32,37|45,46|48,51|54,59|64,66|68,68|70,70|72,73|76,76|87,87|91,92|98,98 Q:0,4|7,7|9,9|11,11|13,15|18,21|23,23|31,31|38,44|47,47|52,53|60,63|67,67|69,69|71,71|74,75|77,86|88,90|93,97 EEEEE??T-T?T-TTT-?BGGG-S?----??S------SEEEEEE--E----ET------TEEE???T-T?B??TT?EEEEEEETTT-HHH--HHHHH? 2FY8|A PF02081.10_TrpBP_seed 10 77 !Q:0,9|19,19|27,27|31,32|40,40|43,43|49,50|74,76 Q:10,18|20,26|28,30|33,39|41,42|44,48|51,73 ?????--???EEEEEESSS?EEEEEEE?SSS??EEEEEEE?TT?EEEEE??SSEEEEEEESSEEEEETTEEEEE??? 2ZP9|A PF02082.15_Rrf2_seed 118 94 !Q:0,2|4,4|18,20|23,23|25,25|29,32|34,34|41,42|45,45|47,48|69,69|73,73|80,80|84,84 Q:3,3|5,17|21,22|24,24|26,28|33,33|35,40|43,44|46,46|49,68|70,72|74,79|81,83|85,93 ??-B?HHHHHHHHHHHHH---HH-H?TTS?---B?HHHHHH--HS-S??HHHHHHHHHHHHHTTSEEEE?STT?EEEESS?GGG?BHHHHHHHH 4FX0|A PF02085.11_Cytochrom_CIII_seed 24 158 !Q:0,4|7,24|27,28|37,38|41,41|43,44|46,46|52,52|54,65|69,69|73,74|76,77|80,90|93,93|97,98|105,105|108,108|110,117|146,148|153,153 Q:5,6|25,26|29,36|39,40|42,42|45,45|47,51|53,53|66,68|70,72|75,75|78,79|91,92|94,96|99,104|106,107|109,109|118,145|149,152|154,157 ?-???SS??????????--------SS??EEEEHHHH--HH-T?-S?STTTS?S------------SSS?GGG--T??SS---------??GG-GTT??HHHHHH?TT?T--------TSHHHHHHHHTTSHHHHHHHHHHTTTTS???TTTH-HHHB 2A3M|A PF02086.10_MethyltransfD12_seed 27 319 !Q:0,0|3,4|16,16|18,23|25,25|27,27|33,33|36,36|43,50|59,59|68,68|73,81|91,96|102,105|114,122|130,132|137,137|142,147|162,164|166,166|170,170|172,174|176,176|179,180|182,189|205,207|214,214|222,224|227,228|233,250|253,254|269,273|278,278|286,292|294,294|304,306|313,318 Q:1,2|5,15|17,17|24,24|26,26|28,32|34,35|37,42|51,58|60,67|69,72|82,90|97,101|106,113|123,129|133,136|138,141|148,161|165,165|167,169|171,171|175,175|177,178|181,181|190,204|208,213|215,221|225,226|229,232|251,252|255,268|274,277|279,285|293,293|295,303|307,312 ?TT??GGGHHHHHHHS?S------S?S?EEETT?TT?HHHHHH------??SEEEEEES?HHHHHHHH-HHHH--------?HHHHHHHHH------HHHHH--??HHHHHHHH---------GGGGSSH---HHHS?HHHH------HHHHHHHHHHBGGG???B?TTS?B???B?SS??S----????HHHHHHHHHHHHHSE---EEEEES?GGGGGTT?-?TT?-EEEE??????????????????SS??HHHHHHHHHHHHHH-----HTTT?EEEEEEE-------S?HHHHHHTTT---SEEEEE?????? 1YF3|A PF02087.10_Nitrophorin_seed 3 181 !Q:0,1|3,7|10,11|19,20|30,30|33,37|75,75|89,89|92,93|97,99|112,112|129,131|142,145|157,158|170,173|175,175|179,180 Q:2,2|8,9|12,18|21,29|31,32|38,74|76,88|90,91|94,96|100,111|113,128|132,141|146,156|159,169|174,174|176,178 ??S?????TT??HHHHSSS-?EEEEEEEES?TT-????EEEEEEEEEETTEEEEEEEEEETTTTEEEEEEEEEEE?SSSSEEEEEEEEE?TT??EEE???TTEEEEEEEEEE?SSEEEEEEEEEETTEE???EEEEEESSTT????HHHHHHHHHTT??GGGSEEGGGTT????H-HHH?? 2AT5|X PF02089.10_Palm_thioest_seed 2 279 !Q:0,0|4,6|11,12|15,16|18,19|37,38|42,44|59,59|74,74|80,80|100,101|104,104|113,114|117,117|119,119|121,121|124,125|129,129|152,152|159,160|171,171|183,184|194,194|205,205|217,217|220,220|223,223|226,226|229,229|251,251|263,265|278,278 Q:1,3|7,10|13,14|17,17|20,36|39,41|45,58|60,73|75,79|81,99|102,103|105,112|115,116|118,118|120,120|122,123|126,128|130,151|153,158|161,170|172,182|185,193|195,204|206,216|218,219|221,222|224,225|227,228|230,250|252,262|266,277 ?TTS???EEEE??TT??S??TTTHHHHHHHHHHHSTT??EEE???SSSHHHHHHHHHHS?HHHHHHHHHHHHHT?GGGTT?EEEEEETTHHHHHHHHHHH??SS?EEEEEEES??TT?B?S?TT??STT?HHHHHHHHHHHHHHTSTTHHHH?TGGGGB??STTHHHHHHH?SSHHHHTTSSS??HHHHHHHHT?SEEEEEEETT?SSSSSGGGGGT?EE?TT?SS?EE?GGGSHHHHTTSSSHHHHHHTT?EEEEEESSSTT???HHHHHHHTSGGG? 3GRO|A PF02091.10_tRNA-synt_2e_seed 9 290 !Q:16,16|19,22|25,26|44,44|55,55|59,60|63,64|67,68|81,82|98,99|104,104|110,111|147,147|150,151|168,168|205,206|229,231|254,256|282,284|286,289 Q:0,15|17,18|23,24|27,43|45,54|56,58|61,62|65,66|69,80|83,97|100,103|105,109|112,146|148,149|152,167|169,204|207,228|232,253|257,281|285,285 HHHHHHHHHHHHHTTT?EE????SS??SSGGGSHHHHTTTSSSS?EEEEEEEEEE?GGG??TT??SS??SEEEEEEEEEES??TTHHHHHHHHHHHTT??GGGS?EEEEE??EEETTTTEEEEEEEEEETTEEEEEEEEEEEETTEE?SS??EEEEEEHHHHHHHHTT?SSGGGSEEEEETTEEEEHHHHHHHHHHHHHHHHHHT??HHHHHHHHHHHHHHHHHHHHTT--?HHHHHHHHHHHHHHHHHHHHHT???HHHHHHHHHHHHHHHHHHHHHHHHH---H???? 3RF1|A PF02093.11_Gag_p30_seed 6 211 !Q:2,5|17,18|22,22|38,40|53,53|68,68|70,70|76,78|87,87|90,94|122,185|188,210 Q:0,1|6,16|19,21|23,37|41,52|54,67|69,69|71,75|79,86|88,89|95,121|186,187 EE????HHHHHHHHHTS??TTT?HHHHHHHHHHHHHHH???HHHHHHHHHHHS?HHHHHHHHHHHHHT?B?TTSSB???HHHHHHHS?SS?????TTSHHHHHHHHHHHHHHHHHHHHHHHH----------------------------------------------------------------HH??????----------------- 3BP9|A PF02097.10_Filo_VP35_seed 4 336 !Q:0,211|223,223|228,228|241,244|250,250|266,267|286,288|292,292|294,294|299,299|308,310|313,314|325,325|329,329|335,335 Q:212,222|224,227|229,240|245,249|251,265|268,285|289,291|293,293|295,298|300,307|311,312|315,324|326,328|330,334 ------------------------------------??????????????----------------------------------------------------------------------------------------------------------------??????????????????????????????????????????????????HHHHHHHHHTT?SSSS?HHHHHHHHHHHH----HHHHT?HHHHHHHHHHHHHTT??HHHHHHHHHHHSGGGGSS???EEE?S?GGGS?GGGGGGEE???SS??GGGTEEEEEE?TTS?EEEEE? 3L28|A PF02098.11_His_binding_seed 13 296 !Q:4,5|17,17|25,25|29,29|36,36|55,65|73,74|78,78|92,93|96,97|100,105|113,117|119,120|130,132|136,137|141,167|171,171|173,173|177,178|180,213|219,220|222,222|227,283|296,296 Q:0,3|6,16|18,24|26,28|30,35|37,54|66,72|75,77|79,91|94,95|98,99|106,112|118,118|121,129|133,135|138,140|168,170|172,172|174,176|179,179|214,218|221,221|223,226|284,295 HGGG??HHHHHHHHHHS?EEEEEES?SEE-TTTEET?EEEEEEEEEEETTTTEEE-----------EEEEEEE--TTE-EEEEEEEEEEEEE??TT?-SS?----?EEEEEET-----T??EEEEEEEEE---ETT--EEE---------------------------EEE?S?SSS??E----------------------------------EEEEE--S?SSSE---------------------------------------------------------EHHHHHHHHHHT- 3BU9|A PF02099.12_Josephin_seed 10 221 !Q:0,3|5,8|19,46|48,49|51,51|73,77|88,91|93,93|102,102|115,115|121,122|132,136|140,140|147,156|168,176|184,184|187,187|190,191|195,195|211,211|219,220 Q:4,4|9,18|47,47|50,50|52,72|78,87|92,92|94,101|103,114|116,120|123,131|137,139|141,146|157,167|177,183|185,186|188,189|192,194|196,210|212,218 ????S--??HHHHHHHHTT----------------------------S??S?HHHHHHHHHHHHHHHHHHHHT???--SHHHHHHHHT--??S?SSSTTTTS?HHHHHHHHHTTT?EEEET--TSHHHHHHT?---?STT?SEEEEE----------ETTEEEEEEEE---------TTEEEEE?TT?SS-?EEE?HHHHHHHHHHHHHHT?EEEEEES-? 3O65|A PF02100.12_ODC_AZ_seed 28 188 !Q:0,0|4,5|9,14|20,39|44,45|49,49|52,55|58,99|114,114|116,119|125,127|130,133|145,146|150,165|168,168|171,177|179,180|186,187 Q:1,3|6,8|15,19|40,43|46,48|50,51|56,57|100,113|115,115|120,124|128,129|134,144|147,149|166,167|169,170|178,178|181,185 ?TTS??EEE------EEEEE--------------------TTEE--EEE?SS-???SS?----------------------------------------?SHHHHHHHHHHHHH-H????EEEEE???SS?---HHHHHHHHTTT??EEE???-?-----------SS?SS------?S??EEEEE?? 1ZO0|A PF02102.10_Peptidase_M35_seed 4 377 !Q:0,193|198,199|228,228|238,240|260,260|263,263|266,266|272,272|276,278|281,282|295,295|302,303|306,307|311,313|325,325|332,333|335,338|347,347|364,370|376,376 Q:194,197|200,227|229,237|241,259|261,262|264,265|267,271|273,275|279,280|283,294|296,301|304,305|308,310|314,324|326,331|334,334|339,346|348,363|371,375 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?EEES??THHHHHHHHHHHHHHHHHHHHHHHHHHS?HHHHHHHHS???HHHHHHHHHHHHHHHHHHT?SB?SS?EEESS?SSS???TT??EEEEGGGTEEEE?HHHHHH??SS??STT???HHHHHHHHHHT?TTTSSS??B????SHHHHHTS?HHHHHTBHHHHHHHHH-------HHHHT? 2X3A|A PF02110.10_HK_seed 9 282 !Q:7,8|14,15|31,31|35,38|52,52|57,57|60,61|80,81|86,86|107,108|114,114|122,138|141,142|144,144|162,162|170,170|173,175|180,183|185,202|225,227|235,235|247,250|261,263|278,279 Q:0,6|9,13|16,30|32,34|39,51|53,56|58,59|62,79|82,85|87,106|109,113|115,121|139,140|143,143|145,161|163,169|171,172|176,179|184,184|203,224|228,234|236,246|251,260|264,277|280,281 HHHHHHH??EEEEE??TTTHHHHHHHHHHHT?EEE????TTTHHHHHHHSSE-EEEE?TT??HHHHHHHHHHHHHHHHTT??EEEE?TTBTTBHHHHHHHHHHHHHS??SEEEE?HHHHHHH?????????????????HH--H-HHHHHHHHHHHTSEEEE?SSSEEEE?SS?--EEEE????G------------------GGGGSTTHHHHHHHHHHHHHTT?--SSHHHHH-HHHHHHHHHHH----HHHHHHHTTS--?HHHHHHHHHHHHHH??HH 3RTB|A PF02113.10_Peptidase_S13_seed 9 497 !Q:11,11|17,17|29,30|40,40|42,43|60,60|63,65|73,75|81,81|83,83|91,91|93,95|99,110|118,121|126,128|131,132|134,134|139,139|143,143|145,146|148,148|151,152|162,165|168,170|175,176|186,187|193,194|201,202|205,205|213,214|217,217|220,224|229,229|245,247|254,254|274,274|277,277|279,279|284,289|292,292|300,302|315,315|331,331|334,335|349,349|354,355|359,359|361,361|363,363|367,368|371,371|374,374|387,388|401,401|405,405|407,407|420,423|448,457|460,460|464,464|475,476|496,497 Q:0,10|12,16|18,28|31,39|41,41|44,59|61,62|66,72|76,80|82,82|84,90|92,92|96,98|111,117|122,125|129,130|133,133|135,138|140,142|144,144|147,147|149,150|153,161|166,167|171,174|177,185|188,192|195,200|203,204|206,212|215,216|218,219|225,228|230,244|248,253|255,273|275,276|278,278|280,283|290,291|293,299|303,314|316,330|332,333|336,348|350,353|356,358|360,360|362,362|364,366|369,370|372,373|375,386|389,400|402,404|406,406|408,419|424,447|458,459|461,463|465,474|477,495 HHHHHHHHHHS?GGGTT?EEEEEEEETTT??EEEEESTTS?B??GGGGHHHHHHHHHHHT?TT???EEEEEES???SSSEE?S?EEEEEES?S???TTH------------HHHHHHH----HHTT???EE-?S?EEEE?TTS?S??S?TT??GGGTTSSTT????SS???SSTT??TTEEEEEEE??SSTTS??EEEEES??SS?EEEEEEE--EE?TT?????EEEE?TTSSEEEEEEEEETT???EEEEEE?SSHHHHHHHHHHHHHHHTT?EE?S?EEEE???---SS?EEEEEEE???HHHHHHHHHHHT?HHHHHHHHHHHHHHH-HS??SHHHHHHHHHHHG-GGGT??GGG?B?S?SSS??TT?BB?HHHHHHHHHHGG--GSTTHHHHHHTS?BTT?S?TTTTGGGSSSST----TSTTTTTEEEEEEEETTEEEEEEE----------EE?SSS?EEEEEEEEES?-SSTHHHHHHHHHHHHHHHH?- 2VGJ|A PF02114.11_Phosducin_seed 2 265 !Q:0,16|19,20|36,36|40,83|85,85|95,98|118,124|129,130|143,143|146,146|154,154|174,174|188,189|194,194|198,198|221,221|224,225|238,238|240,264 Q:17,18|21,35|37,39|84,84|86,94|99,117|125,128|131,142|144,145|147,153|155,173|175,187|190,193|195,197|199,220|222,223|226,237|239,239 ????????---??????SS??SSHHHHHHHHHHHHH-HHT???????????????????---------????????????????S?HHHHHHHTT????HHHHHHHHHHHHHHHHHHH???????SEEE??SHHHHHHHHHSS?TT?EEEEEEE?TTSTTHHHHHHHHHHHHHH?TTSEEEEEEHHHH??TTSS?TTT?SEEEEEETTEEEEEETTGGGGS?TT??HHHHHHHHHTTT?S?????????????-------????? 1A0R|P PF02115.12_Rho_GDI_seed 16 221 !Q:0,10|13,13|15,16|19,42|53,53|65,80|97,98|102,102|105,108|114,114|116,116|120,120|123,123|134,134|137,137|152,152|165,168|171,174|179,181|184,187|191,191|202,202|205,208|218,220 Q:11,12|14,14|17,18|43,52|54,64|81,96|99,101|103,104|109,113|115,115|117,119|121,122|124,133|135,136|138,151|153,164|169,170|175,178|182,183|188,190|192,201|203,204|209,217 ???????????SS?S??SS???????---------????????HHHHHTSSTT?HHHHHHHHHHH????---????????-SEEEEEEEEEESSSSS??EEE?SS?--?GGGGT?E-EEE?TT?EEEEEEEEEE?SS?EEEEEEEEEEESSS?EEEEEEEEEEEE???-SS?---EEEE???EE????SSS?SEEEEEEEEE?TT????EEEEEEEEE??? 1QVY|A PF02120.11_Flg_hook_seed 344 108 !Q:8,8|12,13|18,19|25,26|32,34|40,41|43,46|53,54|76,82|85,85|89,89|91,92|96,97|101,107 Q:0,7|9,11|14,17|20,24|27,31|35,39|42,42|47,52|55,75|83,84|86,88|90,90|93,95|98,100 HHHHHHHH-HHT??EEEE??SSGGG??EEEEE---EEETT--E----EEEEEE??SSHHHHHHHHTHHHHHHHHHT-------TT?EEE-E--EEE--ESS?????-? 2RRL|A PF02121.13_IP_trans_seed 4 265 !Q:0,0|12,12|32,32|35,35|49,49|51,51|53,53|69,69|80,80|100,100|121,122|127,129|136,136|142,142|145,145|150,150|154,155|159,159|163,165|169,174|182,184|187,187|190,198|210,211|227,227|248,249 Q:1,11|13,31|33,34|36,48|50,50|52,52|54,68|70,79|81,99|101,120|123,126|130,135|137,141|143,144|146,149|151,153|156,158|160,162|166,168|175,181|185,186|188,189|199,209|212,226|228,247|250,264 ?EEEEEEEEESS?HHHHHHHHHHHHHHHHHHH?BT-TBEEEEEEEEEEE?S-S?EEEEEEEEEEESTTS?HHHHTTSTTS?EEEEEEEEEETTEEEEEEE?GGGTTSEEEEEEEEEESSSS??TTTT???HHHHTT?EEEEE?SS?GGGS?GGG??GGG?GGG???TTT??????TTHHHHH---HT?SS??------?EEEEEEEEEEE??TTTHHHHHHHHHHHH-HHHHHHHHHHHHHTHHHHTT??HHHHHHHHHHHHHHH 1UW5|A PF02123.11_RdRP_4_seed 28 823 !Q:4,4|28,30|45,58|67,68|70,70|72,72|85,90|93,94|101,102|108,108|114,115|120,122|126,126|136,149|158,162|187,192|196,198|223,224|242,243|262,294|313,314|327,328|332,332|346,351|359,391|399,405|414,414|422,422|424,431|433,433|437,438|440,443|446,446|457,459|463,466|471,471|473,474|478,479|483,484|488,491|512,515|525,526|534,564|567,568|575,575|590,601|607,616|629,630|632,633|635,635|640,651|653,655|657,658|660,660|680,694|699,699|702,702|707,718|734,738|741,744|746,747|750,750|759,764|768,768|771,772|774,775|795,800|810,811|815,815 Q:0,3|5,27|31,44|59,66|69,69|71,71|73,84|91,92|95,100|103,107|109,113|116,119|123,125|127,135|150,157|163,186|193,195|199,222|225,241|244,261|295,312|315,326|329,331|333,345|352,358|392,398|406,413|415,421|423,423|432,432|434,436|439,439|444,445|447,456|460,462|467,470|472,472|475,477|480,482|485,487|492,511|516,524|527,533|565,566|569,574|576,589|602,606|617,628|631,631|634,634|636,639|652,652|656,656|659,659|661,679|695,698|700,701|703,706|719,733|739,740|745,745|748,749|751,758|765,767|769,770|773,773|776,794|801,809|812,814|816,822 EEEE?SSHHHHHHHHHHHHHHHHHHTTT???HHHHHTTHHHHHHS--------------EEEEEEEE??S?S?HHHHHHGGGTTS??????SS??SSGGGS??BHHHH?SSGGG??GGGT???SSS?HHHHHHHHH--------------HHHHHTSS---??HHHHHHHHHHHHHHHHHHHHHHHH??????TTS???HHHHTTSBTTHHHHHHHHHHHHTT??SHHHHHHHHHHHHHHTT??SSHHHHHHTTHHHHHHHS???????????-------???????????????HHHHHHHHHHHHHHHTTT??HHHHHHHHHTTT??GGG?HHHHHHHHHGGGG??????HHHHHHT??????????????---------??????????HHHHHTT???????HHHHTHHH-HHHHHGG-G????????B?SSS??B????HH-HHHHHHHTTT???TTS????SSSS?B??EEE??TTS??EEE????HHHHHTTHHHHHHHHHHHHT---?TTBTTTSTT??HHHHHHH???????????--------------------EE??TTTGGG?HHHHHHHHHHHHHH????????????HHHHH----------HHHHHHHHHHHS??B??B?SSSB??----------B???S??B?STHHHHHHHHHHHHHHHHH????????--?????EEEE?SS?EEEE????????????HHHHHHHHHHHHHTT?????EE????B??SS?EEETTEEE??????SSS?SS??S??HHHHHHHHHHHHHHHHHHS??--??HHHHHHHHH--HHH?EEEETTE 2E9T|A PF02126.13_PTE_seed 4 358 !Q:6,6|13,13|17,18|25,25|31,31|35,60|77,78|83,85|90,91|104,104|108,108|112,113|115,126|132,133|148,148|155,156|163,163|166,167|169,170|188,190|195,196|214,215|222,222|226,226|228,230|242,242|247,248|251,253|256,256|259,259|267,267|270,270|286,286|293,297|301,301|315,315|322,325|339,340 Q:0,5|7,12|14,16|19,24|26,30|32,34|61,76|79,82|86,89|92,103|105,107|109,111|114,114|127,131|134,147|149,154|157,162|164,165|168,168|171,187|191,194|197,213|216,221|223,225|227,227|231,241|243,246|249,250|254,255|257,258|260,266|268,269|271,285|287,292|298,300|302,314|316,321|326,338|341,357 EEHHHH?SEEEEE?SEE??TTHHHH?GGGGS?HHH--------------------------HHHHHHHHHHHHHHTT??EEEE???GGGT??HHHHHHHHHHHT?EEE?EEE??S--???-------HHHHT??HHHHHHHHHHHHHT?BTTTTB??SEEEEE?SS--S??HHHHHHHHHHHHHHHHH???EEEE??TTTTHHHHHHHHHHHTT??GGGEEE?SGG-G???HHHHHHHHHTT?EEEE??TT???TT?TT?HHHHHHH?SS?HHHHHHHHHHHHHTT?GGGEEE?????SEE?SSSTTHHHHHHHH?TTGGGH----HHHTHHHHHHHTT??HHHHHHHHTHHHHHHHS 2O4M|A PF02127.10_Peptidase_M18_seed 9 473 !Q:4,4|20,20|24,24|27,28|32,39|42,42|59,59|62,63|66,67|75,78|90,90|105,106|108,108|114,115|126,126|128,128|131,132|140,141|143,144|147,151|161,165|171,172|179,181|184,184|188,205|207,207|220,224|228,230|241,241|243,244|252,252|285,286|296,296|302,302|321,322|325,325|328,332|339,342|345,345|351,352|355,356|365,365|368,371|375,376|380,381|386,387|389,391|407,412|416,418|422,426|437,437|444,444 Q:0,3|5,19|21,23|25,26|29,31|40,41|43,58|60,61|64,65|68,74|79,89|91,104|107,107|109,113|116,125|127,127|129,130|133,139|142,142|145,146|152,160|166,170|173,178|182,183|185,187|206,206|208,219|225,227|231,240|242,242|245,251|253,284|287,295|297,301|303,320|323,324|326,327|333,338|343,344|346,350|353,354|357,364|366,367|372,374|377,379|382,385|388,388|392,406|413,415|419,421|427,436|438,443|445,472 HHHT?SSHHHHHHHHHHHHH-HTT?EE??TTS???--?-?TT?EEEEEETTTEEEEEEE?TT??TT??EEEEEEE????EEEEEEEEEEE-ETTEEEEEEEEESS??G-GGGTT??EEEEEEEEEE?T-TT??EEEEEEE??S??BB?????GGGSTTTTT?????TTTTT??EEEEHH---HH-HHH?????????????---??S?HHHHHHHHHHHT---??GGG---EEEEEEEEEE?S??EEETTTT?EEEETTHHHHHHHHHHHHHHHHHTTSHHHHHH??SEEEEEEES?GGGTS?SSSSTTSTHHHHHHHHHH??SS?TT-----HHHHHG----GG?EEEEE??EE??BTTBGGGS?TT????TTS??EEE??TTTT--S???HHHHHHHHHHHHHHT---???EEE???TTS?????HHHHHHHHHT?EEEEEE?EEESTTSSSEEEESHHHHHHHHHHHHHH 2GLJ|A PF02128.10_Peptidase_M36_seed 31 638 !Q:0,0|6,6|9,10|15,23|29,31|33,33|35,36|42,42|46,46|49,52|54,54|57,59|70,72|75,76|78,79|81,84|87,89|91,96|99,99|102,107|110,110|115,123|129,129|150,151|156,158|160,161|167,168|170,171|178,178|181,199|202,202|207,208|213,213|219,219|222,222|226,386|388,388|394,394|413,413|416,418|421,421|425,436|454,455|458,459|462,463|465,465|473,473|475,477|479,479|484,484|486,486|488,488|492,495|500,506|509,510|513,520|543,546|548,549|552,553|555,563|569,569|588,588|591,592|614,620|636,636 Q:1,5|7,8|11,14|24,28|32,32|34,34|37,41|43,45|47,48|53,53|55,56|60,69|73,74|77,77|80,80|85,86|90,90|97,98|100,101|108,109|111,114|124,128|130,149|152,155|159,159|162,166|169,169|172,177|179,180|200,201|203,206|209,212|214,218|220,221|223,225|387,387|389,393|395,412|414,415|419,420|422,424|437,453|456,457|460,461|464,464|466,472|474,474|478,478|480,483|485,485|487,487|489,491|496,499|507,508|511,512|521,542|547,547|550,551|554,554|564,568|570,587|589,590|593,613|621,635|637,637 ?EEEEE?TT??SGGG-------??EEEEE??-S?T--TTTTT?TTB?SS?---B?SB---SBSSSEEEEE?--TT??S??T----TS???B?-----TT?EE?-????TT?SSGG---------GGHHH-HHHHHHHHHHHHHHHHHHTT??TTTT???S??TTSSS??S??EEEEET?TT?------------------SS?EEEE??STTS?EEEEE?EE?SSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------S?EEGGG?HHHHHHHHHHHHHHHHTT?TT???TT?SHH------------HHHHHHHHHHHHHHHHH??TT??TT??B?SSHHHHT?T---T?SSSS?B?S?TTT????GGGG-------GG??SH--------HHHHHHHHHHHHHHHHHHHHHH????S--SS??E---------ETTEE-SSHHHHHHHHHHHHHHHS?SS??HHHHHHHHHHHHHHHHSSTTH-------HHHHHHHHHTTBSTT?B 4K90|A PF02129.13_Peptidase_S15_seed 48 451 !Q:1,4|13,21|24,24|32,32|37,39|41,41|48,59|63,81|85,88|90,90|92,92|94,100|111,111|117,118|125,125|127,129|132,141|161,161|168,170|173,174|199,213|216,216|227,233|239,240|249,251|254,254|257,279|288,288|304,319|332,332|335,357|359,362|372,373|375,378|381,383|386,387|398,399|402,402|414,414|417,435|437,439|446,446|449,450 Q:0,0|5,12|22,23|25,31|33,36|40,40|42,47|60,62|82,84|89,89|91,91|93,93|101,110|112,116|119,124|126,126|130,131|142,160|162,167|171,172|175,198|214,215|217,226|234,238|241,248|252,253|255,256|280,287|289,303|320,331|333,334|358,358|363,371|374,374|379,380|384,385|388,397|400,401|403,413|415,416|436,436|440,445|447,448 S?--?EEEEEEEE?------??SS?EEEEEEE?SSTT???H-HHHHHH????????????SEE???????????????????EES----S?S?B???????HHHHHHHTTT?EEEEE??TTSTTS?S???TT----------SHHHHHHHHHHHHHHTTSS?EESSTT???EE??TTEEEEEEEEEETHHHHHHHHHHT---------------TT?TTEEEEEEES?-----?SBHHH--HHBSSSSB???TT?TT---------------------??HHHHHHHH?GGGGSHHHHHHHHHH----------------HHHHHHHHHHHH?TT-----------------------T????HHHHTTBGG--G----GG---GG??SEEEEEEETT??SS?THHHHHHHHHS?TT-----------------??E---EEEEES?SS?? 1ZI9|A PF02130.12_UPF0054_seed 159 230 !Q:1,2|5,5|9,10|12,24|32,33|45,61|70,70|83,84|87,88|94,94|96,99|102,105|107,153|171,171|174,178|196,197|199,203|205,205|207,207|209,211 Q:0,0|3,4|6,8|11,11|25,31|34,44|62,69|71,82|85,86|89,93|95,95|100,101|106,106|154,170|172,173|179,195|198,198|204,204|206,206|208,208|212,229 E--EE?SSS??S???----------HHHHHHH--HHTTSHHHHSE-----------------EEEEEEEE?HHHHHHHHHHHH??SS??SEEEE-E????SS????E-----------------------------------------------EEEEEEEHHHHHHHHHH-TT-??--HHHHHHHHHHHHHHHHT--T--???S-S-H---HHHHHHHHHHHHHHHHTT 1TVI|A PF02132.10_RecR_seed 192 49 !Q:1,1|17,17|20,20|24,25|29,30|33,36|38,38|43,43|47,47 Q:0,0|2,16|18,19|21,23|26,28|31,32|37,37|39,42|44,46|48,48 H-HHHHHHHHHHHHHHH?EE?TTT??EES--SS----S?HHHH?TTS-E 3VDP|A PF02133.10_Transp_cyt_pur_seed 14 478 !Q:0,2|4,4|7,10|23,23|26,26|35,35|41,41|71,73|83,84|97,97|124,130|133,145|194,197|204,207|209,212|215,216|218,218|245,247|250,251|280,280|283,285|287,287|290,294|304,305|314,314|341,343|346,347|363,363|366,369|374,375|378,378|380,380|386,386|388,388|406,408|415,418|424,424|426,427|432,432|449,462 Q:3,3|5,6|11,22|24,25|27,34|36,40|42,70|74,82|85,96|98,123|131,132|146,193|198,203|208,208|213,214|217,217|219,244|248,249|252,279|281,282|286,286|288,289|295,303|306,313|315,340|344,345|348,362|364,365|370,373|376,377|379,379|381,385|387,387|389,405|409,414|419,423|425,425|428,431|433,448|463,477 ???G-GG????HHHHHHHHTGGG?SH-HHHHHHHH-HHHHS?HHHHHHHHHHHHHHHHHHHHHHSHHHHTT???HHHHTTTTS?-TTTTHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHTTT?---???HH-------------HHHHHHHHHHHHHHHTHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHTT?--?HHHHHH----S?--?SS??S?HHHHHHHHHHHHHHHHTTTHHHHTTS???SS??HHHHHHHHHHHHHHHHHHHHHHHHHHHH-HS?--S?HH-----HHHHHHHTS??HHHHHHHH-HHHHHHTTHHHHHTHHHHHHHHTSST---TT??HHHHHHHHHHHHHTT?GG----GTTT--TS?S?TTTSS?S?HHHHHHHHHHHHTTTTT???HHHHTB----SSSTT?B--TTTB?HHHHHHHHHHHHTTTT?-------------GGGHHHHHHHHHHHT 2JLO|A PF02134.16_UBACT_seed 128 91 !Q:0,2|5,5|27,50|59,59|62,66|78,79|90,90 Q:3,4|6,26|51,58|60,61|67,77|80,89 ???TT?TTSSHHHHHHHHHHHHHHHTT??-?---?---------------?HHHHHHHH-TT?????HHHHHHHHHHH--HHHHHHHHTT? 4II2|A PF02135.11_zf-TAZ_seed 22 98 !Q:15,36|39,42|54,54|57,71|86,87|91,93 Q:0,14|37,38|43,53|55,56|72,85|88,90|94,97 HHHHHHHHHHHHHHH--???-----------------TT???-TTHHHHHHHHT?TT??????---??????HHHHHHHHHHHHTT??STT-??STTH 1U2N|A PF02136.15_NTF2_seed 43 158 !Q:15,20|29,31|42,59|74,76|78,85|96,102|122,128|140,140|142,144|147,147 Q:0,14|21,28|32,41|60,73|77,77|86,95|103,121|129,139|141,141|145,146|148,157 HHHHHHHHHHHHHHH-----?GGGGGGGE---EEEEEEEETT?---------------??EESHHHHHHHHHHH???S------?-EEEEEEEEEE-------EEGGGEEEEEEEEEEESTT??-?---EEEEEEEEEEE?S---TT?EEEEEEEEEE 1OHS|A PF02137.13_A_deamin_seed 59 723 !Q:4,6|8,9|11,12|15,16|20,20|22,26|29,30|53,53|56,59|64,64|66,69|71,84|87,88|93,102|106,106|118,120|127,194|197,198|203,271|274,274|277,277|280,281|284,293|299,303|306,311|315,317|325,335|340,340|351,356|364,365|367,377|380,385|393,394|398,415|418,422|425,431|435,510|512,512|515,520|522,524|526,554|562,576|578,578|581,581|587,590|595,603|608,610|625,630|635,640|644,644|647,648|651,662|671,674|689,707|713,720 Q:0,3|7,7|10,10|13,14|17,19|21,21|27,28|31,52|54,55|60,63|65,65|70,70|85,86|89,92|103,105|107,117|121,126|195,196|199,202|272,273|275,276|278,279|282,283|294,298|304,305|312,314|318,324|336,339|341,350|357,363|366,366|378,379|386,392|395,397|416,417|423,424|432,434|511,511|513,514|521,521|525,525|555,561|577,577|579,580|582,586|591,594|604,607|611,624|631,634|641,643|645,646|649,650|663,670|675,688|708,712|721,722 EEEE???B??G--GG??TTS?S----?SB??HHHHHHHHHHHHHHHHHHHHHH?HH----HHHH?S----E--------------EE?-TTSS----------EEE?TTEEEEEEESS??-TTHHHH?????------------------------------------------------???????????????TT??EEEE---------------------------------------------------------------------TT?SS?EE??SS?-----????HHHHH-----TT---???EEE--?HHHHHHH-----------HHHH?SSHHHHHTTB--????EEEEEES--S?--------??HH------HHHHHHT--GGG------------------TT?????TT?????-?EEE----------------------------------------------------------------------------E?SS??????S???S-----------------------------EEEEEET---------------T?SS?EEEET----TTTE---------ETTS???TTSHHHHHHHHHHH------HTTS?-----GGG?SS??SS??----------SHHHHHHT?---HHHHHHHHHHHHHH-------------------HHTTS???-????GG 1ZY7|A PF02138.13_Beach_seed 145 393 !Q:1,2|11,11|25,26|29,29|33,35|37,39|41,43|47,48|50,55|57,59|61,63|68,69|73,74|77,80|83,84|93,93|99,102|105,138|140,143|148,148|150,153|164,165|170,170|182,184|189,194|203,203|206,207|209,209|212,216|218,221|226,232|234,234|240,240|243,247|249,253|257,257|259,259|262,262|264,268|271,275|278,278|281,285|313,316|327,327|331,332|334,334|342,343|345,348|351,352|354,354|360,362|372,385|388,392 Q:0,0|3,10|12,24|27,28|30,32|36,36|40,40|44,46|49,49|56,56|60,60|64,67|70,72|75,76|81,82|85,92|94,98|103,104|139,139|144,147|149,149|154,163|166,169|171,181|185,188|195,202|204,205|208,208|210,211|217,217|222,225|233,233|235,239|241,242|248,248|254,256|258,258|260,261|263,263|269,270|276,277|279,280|286,312|317,326|328,330|333,333|335,341|344,344|349,350|353,353|355,359|363,371|386,387 H--HHHHTTSS?HHHHHHHHHHHHT??SS?GGG???B???B???SSS--S?----?T---T--?GGGB??TTS-?HH----HH-?HHHHHHHH-HHHHH-???SS----------------------------------S???-SBSS?S?--?HHHHHHHHTT--STTH-HHHHHHHHTSS???TTTS?----?BHHHHHHH-HH--H?TT??-??B---?GGGG-------T?GGGGS?TT?????B?----TTS?B?SS?B?---?TT--?--SS-HH-----HHHHHHHHHHHSHHHHTTHHHHHHHHT----STTSSHHHHH-HHT??B?GGGSTTS??G----GG??S-HHHHH---HHHHHHHHH??----???-???-SS????? 1MI1|A PF02140.13_Gal_Lectin_seed 126 129 !Q:2,2|6,9|14,14|22,24|29,29|31,32|34,38|43,59|61,62|64,67|69,69|77,81|86,86|90,92|94,94|96,96|101,106|108,108|110,110|114,115|120,124 Q:0,1|3,5|10,13|15,21|25,28|30,30|33,33|39,42|60,60|63,63|68,68|70,76|82,85|87,89|93,93|95,95|97,100|107,107|109,109|111,113|116,119|125,128 EE?SSS--?-EEEE-EEEEEBS?--SSSS?T--T??---GGGT????-------------B??T----T-HHHHHHH-----HHTT?SEE?-?B?S-HHHH---??-S-S-TTS??EEEE-----EEEE 2JXA|A PF02141.16_DENN_seed 40 220 !Q:0,2|12,13|18,18|33,33|35,47|57,57|62,65|67,99|108,112|119,119|133,133|135,135|143,143|162,164|171,172|180,180|182,182|185,185|197,199|205,207|209,209|213,214 Q:3,11|14,17|19,32|34,34|48,56|58,61|66,66|100,107|113,118|120,132|134,134|136,142|144,161|165,170|173,179|181,181|183,184|186,196|200,204|208,208|210,212|215,219 ---EEEEEEESS??HHHH-HHHHHHHHHHHHTT?H-------------HHHHHHHHH-HHHS????S??????------??--????????-????--??BTTSHHHH-----HHHHHS?HHHHHHHHHHHTT-T?EEEEEES?HHHHHHHHHHHHHTTTTS???SEEESS??GGGGGGG-G?SS?EEEEEETTTHH---HHHTS???S?EEE--ETTTT 3TW8|A PF02142.17_MGS_seed 164 135 !Q:9,9|13,13|15,17|22,22|27,27|32,32|35,36|38,40|43,43|45,86|96,98|105,111|113,115|118,122|129,129 Q:0,8|10,12|14,14|18,21|23,26|28,31|33,34|37,37|41,42|44,44|87,95|99,104|112,112|116,117|123,128|130,134 THHHHHHHH-HHT-T--?EEEE?HHHH-HHHH-HT--T???EE?B??????????????????????????????????????????EEESEEEEE???HHHHHH-------H???HH-----HHHHTS?SSHHH 1WO8|A PF02144.11_Rad1_seed 26 508 !Q:7,7|19,19|23,24|26,35|51,51|73,145|149,149|167,167|169,171|174,235|242,242|246,247|255,257|267,283|285,304|327,327|330,330|339,339|341,342|344,356|359,381|389,389|395,400|406,406|409,409|411,447|455,466|468,468|488,488|499,500 Q:0,6|8,18|20,22|25,25|36,50|52,72|146,148|150,166|168,168|172,173|236,241|243,245|248,254|258,266|284,284|305,326|328,329|331,338|340,340|343,343|357,358|382,388|390,394|401,405|407,408|410,410|448,454|467,467|469,487|489,498|501,507 SEEEEES?THHHHHHHHTT?SSS--E----------EEEEEETTEEEEEEE-ETTTEEEEEEEEGGGSSEEEE-------------------------------------------------------------------------SSS?EEEEEEHHHHHHHHTTT?S???TT???-----------------------------------------------------------EEEEEE?STT??EEEEEEE---TTEEEEEEE??---------------B???--------????????-TTTEEEEEEEEGGGGHHHHHTS?TT-SSEEEEEE?S--S-------------SS-----------------------SEEEEEE-ETTEE------EEEEE?TT?S-------------------------------------SEEEEEE?-----------S?EEEEEEHHHHTTHHHHHHH?SEEEEEEETT??EEEEEEE 1W60|A PF02145.10_Rap_GAP_seed 54 390 !Q:2,4|6,10|24,56|62,66|68,69|72,73|77,79|82,82|86,89|94,94|96,104|106,106|117,123|126,141|144,144|154,154|161,164|167,168|170,207|212,213|216,220|229,301|310,313|317,320|323,326|329,329|333,334|358,362|370,371|381,387 Q:0,1|5,5|11,23|57,61|67,67|70,71|74,76|80,81|83,85|90,93|95,95|105,105|107,116|124,125|142,143|145,153|155,160|165,166|169,169|208,211|214,215|221,228|302,309|314,316|321,322|327,328|330,332|335,357|363,369|372,380|388,389 HH???S?--?-HHHHHHHHHHSEE---------------------------------EESTT--??-S??TT??SSS?--TT?SEE----EEEE?S---------S?EEEEEEGGGS??----?TT---------------?TT?HHHHHHHTT?SEEEEE----ES--S?????---------------------------------GGGS??SS?---?EEEEEEEE--------------------??????----------------------------------------------?EEEEEEEE?---TTS?-??SS???-TT?EEE--SSHHHHHHHHHHHHHHHHHHTTS-----HHHHHHH--HHHHHHHHH-------HH 1SRQ|A PF02146.12_SIR2_seed 20 254 !Q:0,0|9,11|15,15|27,30|32,32|45,45|57,61|64,66|80,81|88,90|92,92|99,100|109,110|120,121|136,168|170,170|184,198|201,202|205,206|217,218|223,225|239,239|247,250 Q:1,8|12,14|16,26|31,31|33,44|46,56|62,63|67,79|82,87|91,91|93,98|101,108|111,119|122,135|169,169|171,183|199,200|203,204|207,216|219,222|226,238|240,246|251,253 ?GGGGGGGT???SSS-TTSHHHHHHTS?--?S?GGGGGBHHHHHH?HHHHHHHGGGG???--SS???HHHHHHHHHHHTT-?EEEEEE???S?HHHHTT??TTTEEETT??TTEEEETTT??EEEGGGGHHHHHTT???------------------------------B?TTTHHHHHHHSTT???????????????TT??TT??TTTTBEEESS??BTSB??-HHHHHHHHHHTTT?SEEEEES????EET 3GLS|A PF02148.14_zf-UBP_seed 179 191 !Q:0,5|9,40|43,60|64,67|71,72|74,75|79,85|87,96|98,101|109,109|111,111|114,153|160,161|165,167|169,170|172,172|178,179|183,183|185,187 Q:6,8|41,42|61,63|68,70|73,73|76,78|86,86|97,97|102,108|110,110|112,113|154,159|162,164|168,168|171,171|173,177|180,182|184,184|188,190 ?-----SSS?---------------------------??--SS------------------EEE----ETT--T??EEE?-----?B????-----?B??--SHHHHHH-H-HH?-------------------------------------??EEEETT??BTT---B??E-EETTT--TEE?B--?TTH 3MHH|A PF02149.14_KA1_seed 26 50 !Q:3,3|10,13|15,15|17,18|20,20|22,24|32,32|49,49 Q:0,2|4,9|14,14|16,16|19,19|21,21|25,31|33,48 TTT?EEEEEE????T-T--T?S???EEEEEES?HHHHHHHHHHHHHHTT? 3OSE|A PF02150.11_RNA_POL_M_15KD_seed 10 38 !Q:0,1|3,3|7,8|10,10|25,25|30,30|34,34 Q:2,2|4,6|9,9|11,24|26,29|31,33|35,37 ??B?TTT??B?EEEEETTTTEEEEE?SSSS?EEE?SSS 1K83|I PF02151.14_UVR_seed 72 37 !Q:5,5|19,19|30,36 Q:0,4|6,18|20,29 HHHHH-HHHHHHHHHHHTT?HHHHHHHHHH??????? 3PXG|A PF02152.13_FolB_seed 129 176 !Q:9,22|31,34|37,43|47,48|56,60|69,69|75,75|79,84|100,126|129,132|136,141|144,144|151,155|159,159|162,168 Q:0,8|23,30|35,36|44,46|49,55|61,68|70,74|76,78|85,99|127,128|133,135|142,143|145,150|156,158|160,161|169,175 EEEEEEEEE??????????????EEEEEEEE----EE???---?GGG?-SSHHHHS----?HHHHHHHH-HHHHH-SSS---???HHHHHHHHHHHHHHS---------------------------TT----EEE------EE-EEEEEE???-?TTS?SE-------EEEEEEE 1RSI|A PF02153.12_PDH_seed 10 277 !Q:9,10|17,17|19,19|32,32|38,39|47,48|54,54|56,56|70,70|73,73|76,76|81,82|84,85|98,100|104,104|109,112|114,115|120,121|128,128|134,135|138,138|140,140|156,156|161,162|190,191|194,195|198,199|203,203|213,216|222,222|257,260|263,263|266,268 Q:0,8|11,16|18,18|20,31|33,37|40,46|49,53|55,55|57,69|71,72|74,75|77,80|83,83|86,97|101,103|105,108|113,113|116,119|122,127|129,133|136,137|139,139|141,155|157,160|163,189|192,193|196,197|200,202|204,212|217,221|223,256|261,262|264,265|269,276 HHHHHHTTT??SEEEEE?S?HHHHHHHHHHTS?SEEES?-GGGGGGG??SEEEE?S?GGGHHHHHHHHHH-HS?TT?EEEE??S??THHHHHHHHHHG---GGB?EEEE????S??SGGG??SSTTTT?EEEEE??TT-S?HHHHHHHHHHHHHTT?EEEE??HHHHHHHHHHHTHHHHHHHHHHHHHHH--HH??SS??GGG?GGGTTGGGG----GGGGS?HHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHH----TT?HH---HHHHHHHH 3DZB|A PF02154.10_FliM_seed 7 195 !Q:0,9|38,39|59,59|62,62|81,81|96,104|107,110|136,140|152,154|156,157|160,160|194,195 Q:10,37|40,58|60,61|63,80|82,95|105,106|111,135|141,151|155,155|158,159|161,193 ??????????HHHHHHHHHHHHHHHHHHHHHHHHHHTS??EEEEEEEEEEEHHHHHTTS?SS?EEEEEEETTTEEEEEEEE?HHHHHHHHHHHTSS??????---TT????HHHHHHHHHHHHHHHHHHHHHHTTT?????EEEEEESSTTS???S?-TT?EEEEEEEEEEETTEEEEEEEEEEHHHHHHHHTT?- 4FHR|A PF02156.10_Glyco_hydro_26_seed 8 359 !Q:4,5|25,25|28,28|32,35|43,43|57,59|71,73|81,82|86,86|95,96|99,100|108,117|121,122|125,127|130,133|142,142|145,145|151,151|172,176|181,181|183,184|194,194|199,201|224,226|233,234|240,240|245,251|255,255|266,268|271,275|285,285|295,295|297,297|300,301|314,314|323,323|326,334|337,337|355,355|358,358 Q:0,3|6,24|26,27|29,31|36,42|44,56|60,70|74,80|83,85|87,94|97,98|101,107|118,120|123,124|128,129|134,141|143,144|146,150|152,171|177,180|182,182|185,193|195,198|202,223|227,232|235,239|241,244|252,254|256,265|269,270|276,284|286,294|296,296|298,299|302,313|315,322|324,325|335,336|338,354|356,357 SSTT??HHHHHHHHHHHHGGGSSSS?EE?EEE----EEETTTT?SSHHHHHHHHHHS???SEEEEEEEETT???SSGGGGB??TTH-HHHHHHHH--TT-?EEEEEEE??-------?TTS--SS?-?TT????HHHHHHHH?TT-SHHHH-HHHHHHHHHHHHHHHHHTTT---??EEEE?S??TTSSSSTTS?SSTT???HHHHHHHHHHHHHHHHHHHTTS???SEEEEE??BTTSS?TTTT----???TTS?SEEEEEEEES--?TT????-HHHHHTTSS?EEEEEEEES-S?SS??BHHHHHHHHHHH?TTEEEEEE?SG---------GG?GGGSBTHHHHHHSTTEE?TT? 2WHM|A PF02157.10_Man-6-P_recep_seed 2 278 !Q:0,34|40,40|42,42|58,59|62,70|76,76|80,81|87,87|98,99|114,114|125,126|128,128|135,135|137,138|146,146|149,149|161,162|166,167|179,277 Q:35,39|41,41|43,57|60,61|71,75|77,79|82,86|88,97|100,113|115,124|127,127|129,134|136,136|139,145|147,148|150,160|163,165|168,178 ---------------------------????????SSSTT?S?HHHHHHHHHTGGGTT??EE?????????EEEEE?SSS??SSSSS?EEEEEEETTT??EEEEEEEEEEEEEE?SSEEEEEEEE??B?SSSGGG?B??EEEEEEE?TT?SSEEEEEEEEE??SSS??EEEEEEEEGGG??------------------------------------------------------------------------------------------------- 2RL8|A PF02163.17_Peptidase_M50_seed 68 707 !Q:11,11|22,23|28,33|37,37|39,161|164,164|166,172|175,176|194,194|204,620|660,672|675,675|678,678|706,706 Q:0,10|12,21|24,27|34,36|38,38|162,163|165,165|173,174|177,193|195,203|621,659|673,674|676,677|679,705 HHHHHHHHHHH-HHHHHHHHHH--HHHH?-????EEE?S---------------------------------------------------------------------------------------------------------------------------SS?B???????SS--SHHHHHHHHHHHHHHHH-HHHHHHTTT???------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EETTEEHHHHHHHHHHHHHHHTTSSSSSSHHHHHHHHHH-------------HH-HH?HHHHHHHHHHHHHHHHHHHHHHHHHTT? 3B4R|A PF02167.10_Cytochrom_C1_seed 124 443 !Q:0,5|8,8|12,15|34,36|48,57|61,70|74,83|92,93|95,95|98,102|106,111|116,117|122,136|142,144|151,152|154,156|161,163|171,173|185,193|196,222|224,239|244,246|249,249|255,256|260,261|265,285|287,287|291,291|293,293|302,307|310,312|315,369|372,386|403,403|421,421|436,438 Q:6,7|9,11|16,33|37,47|58,60|71,73|84,91|94,94|96,97|103,105|112,115|118,121|137,141|145,150|153,153|157,160|164,170|174,184|194,195|223,223|240,243|247,248|250,254|257,259|262,264|286,286|288,290|292,292|294,301|308,309|313,314|370,371|387,402|404,420|422,435|439,442 ?-----TT?STT????HHHHHHHHHHHHHTGGGT???TTSBGGGGTST----------TTT???-------HHH----------HHHHTTSS--E-EE?----TTT-----?SEEE??TTSB???-----------?SSTTS???TTTTTS??S???SSSS---SHHHHHH???HHHHHHHHHTT?-------?SS-?------------------------?G----------------GGTT???TT?EEESS??SSB??GGG---------------------B?TTS?B?SSSEEESS????-?SS---SS-----------------------------------------------------??TT-??---------???HHHHHHHHHHHHHHHH?TTHHHHHHHHHHHHHHH-HHHHHHHHHHHHHH---HTTT 1SQB|D PF02170.17_PAZ_seed 55 208 !Q:0,0|5,6|16,16|20,21|26,33|41,41|50,57|62,63|69,70|73,76|79,88|91,94|103,109|111,111|114,114|119,119|122,122|125,126|128,165|167,167|170,171|175,175|182,182|186,207 Q:1,4|7,15|17,19|22,25|34,40|42,49|58,61|64,68|71,72|77,78|89,90|95,102|110,110|112,113|115,118|120,121|123,124|127,127|166,166|168,169|172,174|176,181|183,185 ?BHHH--HHHHHHHHS?HHH--HHHH--------HHHHHTT?EEEETTTT--------EEEE??EEETT??TT????SS----------SS????HHHHHHTT???????S-SS?EEEE?SS?TT??S--------------------------------------S?SS??EEE?GGGEEE?STT?????????-???????????? 3O3I|X PF02171.12_Piwi_seed 18 395 !Q:8,9|11,11|14,14|27,28|41,51|68,68|70,72|75,75|80,80|83,85|89,89|92,100|108,126|135,135|137,137|141,142|154,155|157,157|160,160|164,175|190,193|203,204|225,231|234,234|237,241|250,251|253,255|264,285|292,293|299,302|307,307|311,311|317,317|319,321|324,327|338,340|345,345|349,354|361,362|367,370|372,373|376,376|394,395 Q:0,7|10,10|12,13|15,26|29,40|52,67|69,69|73,74|76,79|81,82|86,88|90,91|101,107|127,134|136,136|138,140|143,153|156,156|158,159|161,163|176,189|194,202|205,224|232,233|235,236|242,249|252,252|256,263|286,291|294,298|303,306|308,310|312,316|318,318|322,323|328,337|341,344|346,348|355,360|363,366|371,371|374,375|377,393 EEEEEESS--S?TH-HHHHHHHHHHTS??EEEEEETHHHHS?---------?HHHHHHHHHHHHHHTT?B?-?EE?STTS?GG---GGS?EE---------EEEEEEE??????---------????EEEEEEEE?S-SSS??EEEEEEEESTT??S?TT-HHH------------HHHHHHHHHHHHHS?-??SEEEEEEES??GGGHHHHHHHHHHHHHHHHH-------HH?TT??--?EEEEEEEE??S???EEESSGGG?---------------------BTTTTB??TTEEE---?SSSS?SSB?EEEEE?S???SS????EEEEEEEETT???HHHH-HHH------HHHHTT??TTSS----B??SS?HHHHHHHHHHHHHHHHH?- 1YVU|A PF02172.11_KIX_seed 6 81 !Q:0,3|10,10|27,28|57,57 Q:4,9|11,26|29,56|58,80 ????GGGGGS?HHHHHHHHHHHHHHHS??SSGGGGGSHHHHHHHHHHHHHHHHHHHH?SSHHHHHHHHHHHHHHHHHHHHH 2LQI|A PF02173.12_pKID_seed 17 51 !Q:0,5|13,13|20,20|31,34|38,50 Q:6,12|14,19|21,30|35,37 ??----TTHHHHH-HHHHTT?HHHHHHHHHH----HTT?????-------- 1KDX|B PF02174.12_IRS_seed 32 139 !Q:0,1|9,21|29,31|35,35|40,40|50,61|77,84|87,90|99,99|105,105|113,113|115,118|122,123|135,138 Q:2,8|22,28|32,34|36,39|41,49|62,76|85,86|91,98|100,104|106,112|114,114|119,121|124,134 ??EEEEEEE?----------??HHHHHTT?-?SEE-EEEE?SSEEEEEEE?------?????EEEEEEEEGGGEEEE--------EE-?--SSEEEEEE?TTSTT?SEEEEEE?S?---HHH--HHHHHHHHHHH-??? 1Y19|B PF02176.13_zf-TRAF_seed 10 61 !Q:0,7|9,10|12,12|15,16|18,18|20,22|34,34|38,41|44,47|49,53 Q:8,8|11,11|13,14|17,17|19,19|23,33|35,37|42,43|48,48|54,60 ????-???S??B?TT??S?B-??SSSSTTTTTTS?TTS????SS----S?????HHHHHHT 2YUC|A PF02177.11_APP_N_seed 15 125 !Q:1,11|15,16|21,21|25,28|33,33|37,37|41,45|47,49|53,53|63,63|67,67|74,74|76,76|78,78|82,86|89,92|94,102|106,107|115,123 Q:0,0|12,14|17,20|22,24|29,32|34,36|38,40|46,46|50,52|54,62|64,66|68,73|75,75|77,77|79,81|87,88|93,93|103,105|108,114|124,124 S??---------EEE??TTSB?EEE?---TTTS?EEE?TTS?---?B???SHH-HHHHHHHHH?TTS?EEEEEE?S-S?EEE?????SS?---S?????---?EEE??EEEEESS?????????T 3KTM|A PF02179.11_BAG_seed 63 102 !Q:11,11|23,25|30,36|45,45|52,52|60,60|62,63|67,74|95,98 Q:0,10|12,22|26,29|37,44|46,51|53,59|61,61|64,66|75,94|99,101 HHHHHHHHHHH-HHHHHHHHHHH---HHTT??---??HHHHHHHH-HHHHHH-HHHHHHH-H--TTT-------?HHHHHHHHHHHHHHHHHHHH----HHH 4HWH|A PF02180.12_BH4_seed 11 27 !Q:21,22 Q:0,20|23,26 GHHHHHHHHHHHHHHHHHHHT??GGGT 1OHU|A PF02181.18_FH2_seed 48 547 !Q:0,6|9,9|11,16|18,50|54,55|58,67|76,76|79,91|103,148|150,150|154,154|169,173|185,185|187,187|190,204|213,213|216,218|226,227|229,236|239,239|242,248|252,252|256,258|267,267|308,308|332,333|335,335|339,339|349,349|351,351|353,353|357,357|359,360|372,416|418,418|426,426|429,429|439,439|464,473|477,478|516,518|520,521|524,527|530,530|547,547 Q:7,8|10,10|17,17|51,53|56,57|68,75|77,78|92,102|149,149|151,153|155,168|174,184|186,186|188,189|205,212|214,215|219,225|228,228|237,238|240,241|249,251|253,255|259,266|268,307|309,331|334,334|336,338|340,348|350,350|352,352|354,356|358,358|361,371|417,417|419,425|427,428|430,438|440,463|474,476|479,515|519,519|522,523|528,529|531,546 ???????SS?B??????B?------------------------------?-GGG??TT---------?HHHHTTTS?TT?-----------?SHHHHHHHHHB????????????-------------------???????????????B?SSS?HHHHHHHHHHHHHH--???HHHHHHHHHHT?T-TT??-------------HHHHHHHH-HH???HHHHHTT--T--------TS?SS------?TTB?HHH---HHHHHHTT-STTHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHTTTSSS-?S?SEE?GGGGGGGGG?B?T-TSS?B--HHHHHHHHHHH---------------------------------------------H?GGGGGHH-HH?STHHHHHHS?HHHHHHHHHHHHHHHHHHHHHHHT???-----??STT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT---T??TT----TS?HHHHHHHHHHHHHHHH- 2J1D|G PF02182.12_SAD_SRA_seed 34 195 !Q:0,3|5,6|9,10|13,13|28,29|32,32|42,52|61,61|64,64|66,66|69,69|77,77|79,79|82,83|85,85|88,88|90,93|95,95|97,99|101,101|114,116|120,120|123,123|130,130|144,148|152,152|156,156|173,173|177,177|188,192|195,195 Q:4,4|7,8|11,12|14,27|30,31|33,41|53,60|62,63|65,65|67,68|70,76|78,78|80,81|84,84|86,87|89,89|94,94|96,96|100,100|102,113|117,119|121,122|124,129|131,143|149,151|153,155|157,172|174,176|178,187|193,194 ????S??TT??TT?EESSHHHHHHHTSS??SS?SEEEETTTE-----------EEEEEESS?ST-T?EE?SSEEEEE?S?SB??T-TT?S?-??B?S???S?HHHHHHHHHSSS???TTT?EE?TTGGGS?EEEEEEEGGGGGG?----SSS?SSS-EEEEEEEEEEEEEEEE?TTS-SEEEEEEEEE?---?SS- 3F8J|B PF02185.11_HR1_seed 106 85 !Q:27,31|35,36|38,45|79,79|83,84 Q:0,26|32,34|37,37|46,78|80,82 HHHHHHHHHHHHHHHHHHHHHHHHHHH-----HSS??S?-------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?SSS?? 2RMK|B PF02186.10_TFIIE_beta_seed 12 76 !Q:0,0|21,22|24,24|26,26|36,36|39,40|55,55|61,62|65,65|70,71|75,75 Q:1,20|23,23|25,25|27,35|37,38|41,54|56,60|63,64|66,69|72,74 ?TTHHHHHHHHHHHHHHHHHT??S?B?HHHHHHHHT?SS??HHHHHHHHTTHHHH?TTEEE?-SS-SEEE??TTT? 1D8J|A PF02187.12_GAS2_seed 4 75 !Q:0,0|14,16|20,22|33,33|68,68 Q:1,13|17,19|23,32|34,67|69,74 ?HHHHHHHHHHTSS???SSS???EEEEETTEEE-ETTEEEEEEEETTTEEEEEETTEEEEHHHHHHHH?HHHHTS 1V5R|A PF02188.12_GoLoco_seed 46 24 !Q:0,2|12,16|20,20|22,23 Q:3,11|17,19|21,21 ???HHHHHHHHS-????SSS?B?? 1KJY|B PF02189.10_ITAM_seed 12 22 !Q:8,21 Q:0,7 HHHHHTTT??????-??????? 1A81|B PF02190.11_LON_seed 158 684 !Q:0,1|9,14|17,17|23,23|25,28|32,42|45,50|57,79|82,82|86,91|96,147|150,150|153,157|160,168|173,223|229,233|237,240|242,263|265,266|268,269|271,321|328,329|333,333|337,341|345,345|348,424|429,432|434,448|452,500|502,502|506,511|519,521|525,558|565,611|615,615|618,619|626,626|630,632|636,636|642,644|648,648|650,656|663,663|667,669 Q:2,8|15,16|18,22|24,24|29,31|43,44|51,56|80,81|83,85|92,95|148,149|151,152|158,159|169,172|224,228|234,236|241,241|264,264|267,267|270,270|322,327|330,332|334,336|342,344|346,347|425,428|433,433|449,451|501,501|503,505|512,518|522,524|559,564|612,614|616,617|620,625|627,629|633,635|637,641|645,647|649,649|657,662|664,666|670,683 ??EEEEESS??-?-?BT?EEEEE-E?--?TTT-----------HH------HHHHHH-----------------------TT-TTE------EEEE----------------------------------------------------EB?SS---??SS?-------?SSSB--------------------------------------------------?SEEEE-----EEE??-?B--------------------??T--T--S?--------------------------------------------------EEEEEE--EEE-EEE?----SEE-EE-----------------------------------------------------------------------------ETTE----E---------------EEE????-----------------------------------------????S?HHH------HHHHHHH---HHH----------------------------------HHHHHH-----------------------------------------------HHH?SS-?HHHHHH-TTS???HHH-HHHHH---HHT-S?----??HHHHHH-HHH???HHHHHHHHHHHHHH 3M65|A PF02192.11_PI3K_p85B_seed 13 81 !Q:9,9|31,33|47,47|50,50|52,54|57,58|65,65|70,70|77,79 Q:0,8|10,30|34,46|48,49|51,51|55,56|59,64|66,69|71,76|80,80 EEEEEEETT?BHHHHHHHHHHHGGGSTTTTS???GGGEEEEEEBSSS?EE-E???TT--SBSGGG?BSSS?EEEEES???S 4A55|A PF02195.13_ParBc_seed 51 140 !Q:9,16|21,24|40,57|59,60|62,62|64,64|71,75|84,84|96,102|106,110|115,126 Q:0,8|17,20|25,39|58,58|61,61|63,63|65,70|76,83|85,95|103,105|111,114|127,139 EEEEGGGEE---?????HHHH----HHHHHHHHHHHHHHH------------------H??S-S?EEEEEE-----TTEEEEEE?HHHHHHHHHHT------?SEE-----EEEE????--------HHHHHHHHHHHHH 1XW3|A PF02196.10_RBD_seed 10 78 !Q:0,0|16,17|20,20|35,36|49,49|58,58|69,70|77,77 Q:1,15|18,19|21,34|37,48|50,57|59,68|71,76 ?EEEEEETTTEEEEEE??TT?BHHHHHHHHHHTTT??GGGEEEEEEEGG-GSSEEEEE?TTSBGGGGTT-?EEEEEE? 1C1Y|B PF02197.12_RIIa_seed 13 39 !Q:17,18|20,20|30,30|37,38 Q:0,16|19,19|21,29|31,36 TTHHHHHHHHHHHHHHH??S?HHHHHHHHH-HHHHHT?? 2DRN|A PF02198.11_SAM_PNT_seed 15 94 !Q:12,13|15,19|24,25|40,41|44,48|53,56|73,73|75,76 Q:0,11|14,14|20,23|26,39|42,43|49,52|57,72|74,74|77,93 THHHHHHHHHTT??S-----SSTT??HHHHHHHHHHHHHH--HT?????TTTT-???HHHHHHTHHHHHHHHS?H--HHHHHHHHHHHHHHHTT 2QAR|A PF02201.13_SWIB_seed 41 84 !Q:1,2|7,7|15,16|19,21|23,23|41,41|43,43|46,46|51,53|60,61|63,65|68,68 Q:0,0|3,6|8,14|17,18|22,22|24,40|42,42|44,45|47,50|54,59|62,62|66,67|69,83 S??EEEE?TTHHHHT??SE---E-EHHHHHHHHHHHHHHTT?B?SS?SSEE???TTHHHH--T??-SS-EEGGGSHHHHHHHEE 3EQY|A PF02203.10_TarH_seed 88 189 !Q:0,38|40,40|80,80|82,84|87,87|96,96|114,118|122,122|125,125|137,137|153,155|162,162|180,183 Q:39,39|41,79|81,81|85,86|88,95|97,113|119,121|123,124|126,136|138,152|156,161|163,179|184,188 ?---------------------?????????????????T-THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT-T???SS?HHHHHHHH-HHHHHHHHHHHHHHHTS??--?TTS?HH-HHHHHHHHHHH-HHHHHHHHHHHHHTT-??HHHHTS?HHHHHHHHHHHHHHHHH----HHHHH 1WAS|A PF02204.13_VPS9_seed 49 182 !Q:11,11|14,17|38,64|73,77|93,94|96,96|99,100|110,118|120,143|145,146|151,151|153,160|179,180 Q:0,10|12,13|18,37|65,72|78,92|95,95|97,98|101,109|119,119|144,144|147,150|152,152|161,178|181,181 SHHHHHHHHTG-GG?--?SHHHHHHHHHHHHHHHHHHH---------------------------HHHHHHTT?????HHHHHHHHHHHHHHH??T-TH--HHHHHHHHH---------H------------------------S-?TTTS?H--------HHHHHHHHHHHHHHHHHT??T 1TXU|A PF02205.15_WH2_seed 57 31 !Q:0,1|14,20|22,26|29,30 Q:2,13|21,21|27,28 ??TTHHHHHHHHHH??-?--?B??-??EE?? 2VCP|D PF02207.15_zf-UBR_seed 99 114 !Q:0,0|3,4|6,7|10,20|31,38|42,47|49,49|60,61|64,64|70,74|77,77|79,80|83,86|90,96|99,100|102,104|106,107|111,113 Q:1,2|5,5|8,9|21,30|39,41|48,48|50,59|62,63|65,69|75,76|78,78|81,82|87,89|97,98|101,101|105,105|108,110 ?SS??B??TT----------?EEEEETTTBS--------STT----??B?HHHHTTSGGG--GS?EEEEE??---SS?B??TT---?TTS-------BS--S?-?S-?TTT--? 3NIS|A PF02209.14_VHP_seed 15 36 !Q:2,2|13,13|21,21|34,35 Q:0,1|3,12|14,20|22,33 GS?HHHHHHHHSS?HHHHHHS?HHHHHHHHHHTT?? 2RJV|A PF02210.19_Laminin_G_2_seed 208 248 !Q:2,8|10,10|18,21|24,25|28,34|38,41|49,49|53,53|62,77|79,79|86,86|89,102|105,107|110,111|121,136|141,145|155,155|159,200|202,203|209,211|214,214|217,220|223,223|225,227|233,233|235,236 Q:0,1|9,9|11,17|22,23|26,27|35,37|42,48|50,52|54,61|78,78|80,85|87,88|103,104|108,109|112,120|137,140|146,154|156,158|201,201|204,208|212,213|215,216|221,222|224,224|228,232|234,234|237,247 EE?---?-?S?EEEEEEE????SS??SS------?TTS????EEEEEEE-TTE-EEEEEESS----------------S?EEEEES?SS?----------?-?SS?-?EE--EEEEEETTE----------------EEEE-----ETTEEEEEE?SSS??-----------------------------------?????S?-EEESS?-?SS?TT????TT?H---HHHTT?B??EEEEEEEETTE 3VKF|C PF02211.10_NHase_beta_seed 33 275 !Q:0,2|5,6|9,14|16,25|27,30|32,32|50,51|55,77|89,89|94,96|100,100|118,118|120,120|128,131|138,138|141,149|163,166|169,171|174,175|177,178|181,181|186,191|193,197|199,203|209,209|215,215|222,223|229,229|233,237|255,255|257,257 Q:3,4|7,8|15,15|26,26|31,31|33,49|52,54|78,88|90,93|97,99|101,117|119,119|121,127|132,137|139,140|150,162|167,168|172,173|176,176|179,180|182,185|192,192|198,198|204,208|210,214|216,221|224,228|230,232|238,254|256,256|258,274 ???TT??TT????-?S?--???----S-???S?SSHHHHHHHHHHHHHHH--TTS---------------------??HHHHHHHHHTS?HHHH---HHS?HHHHHHHHHHHHHHHHT?S?HHHHHHH----HHHHHH?TT?????????HHHHHHHHHHHHH????EE-??SS??S??TT?EEEE?-????S-----S?????GGGTT?EEEEE-EEEEEE??HHHHT-TTS???-?EEEEEEEEEHHHHHGGG-S?TTEEEEEEEEGGGEEEE 3QXE|B PF02212.13_GED_seed 95 123 !Q:0,3|12,14|38,62|80,81|85,87|93,95|120,122 Q:4,11|15,37|63,79|82,84|88,92|96,119 ????HHHHHHHH---HHHHHHHHHHHHHHHHHHHHHHH-------------------------THHHHHHHHHHHHHHHH??HHH---HHHHT???HHHHHHHHHHHHHHHHHHHHHHHH??? 3ZVR|A PF02213.11_GYF_seed 79 73 !Q:0,0|7,7|9,9|14,14|17,18|33,33|36,37|43,51|54,59|62,65|70,70 Q:1,6|8,8|10,13|15,16|19,32|34,35|38,42|52,53|60,61|66,69|71,72 ?BEEEES-S?SSSS?EE??SBHHHHHHHHHHTS?TT??EEEES---------SS??-???EE----GGGS?SS 1GYF|A PF02214.17_BTB_2_seed 46 116 !Q:20,20|31,48|50,51|55,55|59,59|64,64|66,66|80,82|84,84|86,88|92,92|105,106|110,111|113,113 Q:0,19|21,30|49,49|52,54|56,58|60,63|65,65|67,79|83,83|85,85|89,91|93,104|107,109|112,112|114,115 EEEEETTEEEEEEHHHHTTS-TTSSTTSSGG------------------G--GTB?SSS?SEEE?S?HHHHHHHHHHHHH---S?B???TTS?HHHHHHHHHHTT??GGG--B?HH 1EOF|A PF02216.11_B_seed 6 54 !Q:0,5|18,18|22,22|36,36 Q:6,17|19,21|23,35|37,53 ??????SSHHHHHHHHTT?TTS?HHHHHHHHHHHHH?TTSHHHHHHHHHHHHHH 2OTK|E PF02217.11_T_Ag_DNA_bind_seed 11 102 !Q:0,3|11,13|16,18|28,28|40,45|49,49|56,56|59,59|65,65|73,73|89,90|92,94 Q:4,10|14,15|19,27|29,39|46,48|50,55|57,58|60,64|66,72|74,88|91,91|95,101 ????TTTTTSB???SS???EEEEEEEEE?HHHHHHHHTTG------GGG?EEEEEE-EE?SSSEE-EEEEEEE-EEEHHHHHHHHTTTS??S???EEEBSSH 3QK2|A PF02219.12_MTHFR_seed 12 323 !Q:11,12|19,21|41,43|49,66|78,80|86,86|90,91|107,108|113,136|146,150|153,156|163,163|165,166|168,169|171,176|178,178|180,183|205,207|209,209|225,230|232,232|235,235|238,240|242,242|254,254|256,259|268,268|270,270|273,273|297,301|307,307|310,311 Q:0,10|13,18|22,40|44,48|67,77|81,85|87,89|92,106|109,112|137,145|151,152|157,162|164,164|167,167|170,170|177,177|179,179|184,204|208,208|210,224|231,231|233,234|236,237|241,241|243,253|255,255|260,267|269,269|271,272|274,296|302,306|308,309|312,322 HHHHHHHHTTT??EEEEEE???SSHHHHHHHHHHHHHHHTT?-?SEEEE??????-----???-???HHHHHHHHHHT???EEEEE?STT??HHHHHHHHHHHHTTT??EEEE????????----?????-----??HHHHHHHHH-----TT??-?EEEEEE?T--T??T------T?S?---HHHHHHHHHHHHHTTEEEEEE???S?HHHHHHHHHHHHTTT?----?S?EE?EE???S?HHHHHHHHHHH-T????HHHHHHHT-T?TT?HHHHHHHHHHHHHHHHHHHHHTT---??EEEEE?TT??HHHHHHHHHTT 1ZP4|A PF02221.10_E1_DerP2_DerF2_seed 137 206 !Q:0,1|7,9|11,11|14,14|20,20|27,34|37,39|42,42|48,48|58,58|60,60|62,62|64,65|69,69|79,83|88,88|90,92|95,95|98,98|102,103|113,113|117,121|129,131|134,134|136,137|140,140|143,143|145,145|150,150|154,163|167,167|170,174|180,180|186,186|188,188|191,192|195,196 Q:2,6|10,10|12,13|15,19|21,26|35,36|40,41|43,47|49,57|59,59|61,61|63,63|66,68|70,78|84,87|89,89|93,94|96,97|99,101|104,112|114,116|122,128|132,133|135,135|138,139|141,142|144,144|146,149|151,153|164,166|168,169|175,179|181,185|187,187|189,190|193,194|197,205 ??EEEES---G-GG?SSEEE-EEEEEE--------SS---SB?SSSEE-EEEEEEEES-S?B?S??EEE-EEEEEEETT-----EEEE?B??-SS?SB?EES-?HHHHHHHHS?TTS?--??TTTGGGT???SS?B-?SE-EE-E-EEEE-EEE?--??????-TTS?SE-----EEEEE-EEEEE-T-TE--EE--EEEEEEEEE 2Z64|C PF02222.17_ATP-grasp_seed 23 201 !Q:5,10|19,21|31,35|42,42|44,52|65,78|84,87|94,95|100,100|104,104|110,112|129,132|135,137|148,148|155,155|160,160|168,171|174,178|189,190 Q:0,4|11,18|22,30|36,41|43,43|53,64|79,83|88,93|96,99|101,103|105,109|113,128|133,134|138,147|149,154|156,159|161,167|172,173|179,188|191,200 HHHTS??????EEEESSHH---HHHHHHHHH----?SSEEEE-E?????????EEESSTTTTTTT??????????????EEEEE????SEEEEE??EEEE?TTS?EEEEE???EEEEESSSSEEEEEES????HH---HHHHHHHHHH-HHHHHH?SSEE?EEEEEEE----TT-----EEEEEEEESS??GGGGGHHHHS 3ORQ|A PF02223.12_Thymidylate_kin_seed 25 208 !Q:2,2|7,7|24,27|35,35|49,52|55,57|61,63|78,80|91,91|98,98|109,109|112,114|129,133|141,143|156,168|185,185|198,199 Q:0,1|3,6|8,23|28,34|36,48|53,54|58,60|64,77|81,90|92,97|99,108|110,111|115,128|134,140|144,155|169,184|186,197|200,207 EE?STTS?HHHHHHHHHHHHHHTT??--EEEEESS?SSHHHHHHHHHHH----HS???HHH---HHHHHHHHHHHHHH---HTHHHHHHTT?EEEEES?HHHHHHHHTT-TT???HHHHHHHHHHHHTT--???SEEEEEE-??HHHHHHHHHTTT?---------???HHHHHHHHHHHHHHHH-HSTTEEEEETTS?-HHHHHHHH 1E99|A PF02224.13_Cytidylate_kin_seed 14 164 !Q:6,7|12,14|18,18|20,20|28,28|32,32|48,48|63,66|69,69|82,82|85,85|93,94|111,115|133,133|137,137|139,141|144,144|149,149|152,153 Q:0,5|8,11|15,17|19,19|21,27|29,31|33,47|49,62|67,68|70,81|83,84|86,92|95,110|116,132|134,136|138,138|142,143|145,148|150,151|154,163 HHHHHH??EEEE??-SSS?E-EEETTEE?TTG-GGSHHHHHHHHHHTT?HHHHHHHHHHHHTT??--TT?EEEEESSIIIII?TT?SEEEEEE??HHHHHHHHHHHHHHTT-????HHHHHHHHHHHHHHHHS?SSS?S???TT?EEEE?TT??HHHHHHHHHH 3R20|A PF02225.17_PA_seed 69 175 !Q:0,2|11,42|44,44|47,48|56,57|62,63|67,71|73,74|77,92|94,97|102,105|110,111|114,114|116,116|123,138|143,146|148,148|151,152|155,156|162,163 Q:3,10|43,43|45,46|49,55|58,61|64,66|72,72|75,76|93,93|98,101|106,109|112,113|115,115|117,122|139,142|147,147|149,150|153,154|157,161|164,174 ???EEEEEEEE--------------------------------E?TT??TTTTTTS??TTSE--EEE-----E??SS---------------?H----HHHH----HHHH--HT-T?SEEEEE?---------------SSSS????B?SS??TT??EEEEE-?HHHHHHHHHHH 2CIJ|A PF02226.11_Pico_P1A_seed 31 68 !Q:0,1|6,23|28,31|38,40|43,47|53,54|58,60|64,64|66,67 Q:2,5|24,27|32,37|41,42|48,52|55,57|61,63|65,65 ??EEEE??????????????????EEEE????SSGGGS???TT?????GGGTS??BSS???TTS?S?? 1POV|0 PF02228.11_Gag_p19_seed 2 92 !Q:0,0|9,10|12,13|16,16|35,37|55,55|63,63|72,72|75,75|91,91 Q:1,8|11,11|14,15|17,34|38,54|56,62|64,71|73,74|76,90 ?SSSTTTSS??S??SS?SSTHHHHHHHHHHHHHSS???STTTHHHHHHHHHHHHT?TTSTTTT?TTTHHHHS?SS?STTHHHHHHHHHTTT? 1JVR|A PF02229.11_PC4_seed 203 77 !Q:0,0|2,7|11,12|27,27|38,40|43,43|45,45|49,50|54,54|58,59|63,68 Q:1,1|8,10|13,26|28,37|41,42|44,44|46,48|51,53|55,57|60,62|69,76 ?E------EEE--ETTEEEEEEEETTE-EEEEEEEEEE--?SS-S?EEE--EEE-EEE??HHH------HHHHHHHH 4G06|A PF02230.11_Abhydrolase_2_seed 12 243 !Q:0,3|7,8|11,12|20,21|25,25|27,31|40,40|43,44|52,55|57,57|70,70|73,73|75,77|81,84|86,86|109,122|145,145|148,151|159,161|168,168|171,173|177,177|180,181|190,190|194,194|210,210|222,223|226,227 Q:4,6|9,10|13,19|22,24|26,26|32,39|41,42|45,51|56,56|58,69|71,72|74,74|78,80|85,85|87,108|123,144|146,147|152,158|162,167|169,170|174,176|178,179|182,189|191,193|195,209|211,221|224,225|228,242 ?--?EEE??SS??SEEEEEE??SSS?H-----HHHHHHHH-TT??TTEEEEE????E-EEEGGGTTEEEE?SS?B???STT?--?B?HHHHHHHHHHHHHHHHHHHHTT------------??GGGEEEEEETHHHHHHHHHHTT?SS--??SEEEEES???TTGGGS?SS???STT-TT??EEEEEETT?SSS?HHHHHHHHHHHHHHS?GGGEEEEEETT??SS??HHHHHHHHHHHHHHS 4F21|A PF02232.10_Alpha_TIF_seed 13 357 !Q:0,6|8,19|33,33|46,50|55,57|64,64|68,68|70,70|81,89|92,93|96,98|101,106|165,169|216,216|229,229|237,238|240,240|243,244|254,255|271,274|276,276|281,281|285,285|287,293|297,298|316,356 Q:7,7|20,32|34,45|51,54|58,63|65,67|69,69|71,80|90,91|94,95|99,100|107,164|170,215|217,228|230,236|239,239|241,242|245,253|256,270|275,275|277,280|282,284|286,286|294,296|299,315 ----??-S???----?????HHHHHHHHHHHHT?TTHHHHHHHHHH?????STTS???GGGGTT?GGG?S?HHHHHHHHHH????----?SS??TT???SS??????SSGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?HHHHTTEEEEES?SHHHHSS??S?SB??SEEEETTEE??HHHHHHHHHHHHHTT????B?TTTS?TTS?S???????TTS??HHHHHHHHHHHHHTSTT??-?????????????????????-???????????????? 16VP|A PF02233.11_PNTB_seed 10 520 !Q:0,349|351,352|363,363|371,371|379,379|395,395|402,402|405,405|421,422|439,439|447,448|452,452|458,458|466,470|485,487|490,493|507,507|519,519 Q:350,350|353,362|364,370|372,378|380,394|396,401|403,404|406,420|423,438|440,446|449,451|453,457|459,465|471,484|488,489|494,506|508,518 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------??????????????????????????--??????B??HHHHHHHHHH?SEEEEEE?HHHHHHT?HHHHHHHHHHHHHTT?EEEEEE?TT?SSSTTHHHHHHHHTT??GGGEEEHHHHGGGSTT?SEEEEES??GGG?GGGTS?TTSTTTT?????GGGSSEEEEEESSS???TT????GGGGSTTEEEEES?HHHHHHHHHHH? 1U31|A PF02234.14_CDI_seed 43 66 !Q:0,1|4,9|31,33|45,48|50,51|54,56|58,59|62,63 Q:2,3|10,30|34,44|49,49|52,53|57,57|60,61|64,65 ??SS?--???HHHHHHHHHHHHTTTTHHHHH---HHTEETTTTEE-?--S--SS---S??EE--EE 1JSU|C PF02236.12_Viral_DNA_bi_seed 10 91 !Q:0,3|21,22|29,32|35,38|53,53|56,58|61,62|84,86|89,90 Q:4,20|23,28|33,34|39,52|54,55|59,60|63,83|87,88 ????HHHHHHHHHHHHHHHTT??HHHHHH????TT??--HHHHHHHHHHHHHH?TT???SS??HHHHHHHHHHHHHHHHHHHHT???TT?? 2WB0|X PF02237.12_BPL_C_seed 50 65 !Q:0,1|3,3|8,18|26,27|30,31|36,36|40,52|57,57|62,62 Q:2,2|4,7|19,25|28,29|32,35|37,39|53,56|58,61|63,64 ??S?EEEE??---????--EEEEEEE-?TT??EEEE?SSS------------?EEEE?TTTS?EE 3FJP|A PF02238.10_COX7a_seed 8 57 !Q:0,2|12,12|15,17|23,23|54,56 Q:3,11|13,14|18,22|24,53 ???HHHHHHHHH?SS???TTTTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHTS??? 1V55|J PF02239.11_Cytochrom_D1_seed 8 414 !Q:0,2|25,26|33,34|38,38|44,44|47,47|49,49|70,71|78,79|88,89|93,93|116,117|124,125|128,128|132,133|137,139|146,146|169,169|171,171|181,182|191,191|195,195|206,208|226,226|232,233|236,236|251,251|263,264|268,273|286,286|288,288|290,293|296,297|300,300|306,307|310,310|318,318|327,329|332,335|340,340|347,350|353,354|362,362|374,375|379,380|397,398|401,402 Q:3,24|27,32|35,37|39,43|45,46|48,48|50,69|72,77|80,87|90,92|94,115|118,123|126,127|129,131|134,136|140,145|147,168|170,170|172,180|183,190|192,194|196,205|209,225|227,231|234,235|237,250|252,262|265,267|274,285|287,287|289,289|294,295|298,299|301,305|308,309|311,317|319,326|330,331|336,339|341,346|351,352|355,361|363,373|376,378|381,396|399,400|403,413 ???GGGEEEEEEGGGTEEEEEETTT??EEEEEE??TTE-EEEEE?TT-S?EEEEEETTSEEEEEETTSSS??EEEEEE??SEEEEEEE??STT?TTSEEEEEEEESSEEEEEETTT??EEEEEE??EE?TTT??EES???EEEEEE?SSSSEEEEEETTTTEEEEEETT?S-SEEEEEEEE??TTEEEEEE?TTS?EEEEEEGGGT---EEEEEETTTTEEEEEEE?SSSSB??TT?EEEEETTTEEEEEE?BSSSSEEEEEE??TTT-----?TTTBTSEEEEEE?S?S????EE??TT?SEEEE??TT?SSHHHHT?EEEEEGGG???SS????EEEE?HHHHHT??--SS??EEEEEEE?TTSSEEEEEEE??TTS??EEEEEETTTTEEEEEE??TT??SEEEEEEHHHH 1H9X|A PF02240.11_MCR_gamma_seed 7 249 !Q:0,6|19,19|23,25|27,31|43,43|47,49|53,54|59,63|70,72|80,80|89,89|93,93|96,96|108,108|111,111|116,116|119,119|135,135|143,144|151,151|154,157|161,161|163,163|167,170|173,174|189,189|193,193|201,206|214,218|223,223|227,227|247,247 Q:7,18|20,22|26,26|32,42|44,46|50,52|55,58|64,69|73,79|81,88|90,92|94,95|97,107|109,110|112,115|117,118|120,134|136,142|145,150|152,153|158,160|162,162|164,166|171,172|175,188|190,192|194,200|207,213|219,222|224,226|228,246|248,248 ???????SSHHHHHHHHTT?SSS???B?????HHHHHHHTTTS?TTS???BSS??GGGS?????TTTTTS???HHHHHTB?EEEEEEEE?TTT?SS?HHHHHHHHHHH?SS?EEEE?SS?EEEEEEHHHHHHHHH-HHHHBTT??TTTEEE?SS????TTS?B?TTS????TT??EEEETTTTEEEEEE?TTS?EEEEEEE??????HHHHHTT?????TTSS?GGG?HHHHHHHHHHHHHHHHHHH?S 1HBN|C PF02241.13_MCR_beta_seed 6 255 !Q:1,1|5,5|7,7|18,18|58,58|74,75|93,93|102,102|108,108|110,110|135,135|157,158|181,182|187,188|195,195|212,213|215,216|219,219|224,224|239,239 Q:0,0|2,4|6,6|8,17|19,57|59,73|76,92|94,101|103,107|109,109|111,134|136,156|159,180|183,186|189,194|196,211|214,214|217,218|220,223|225,238|240,254 T?GGG?S?HHHHHHHTTT?HHHHHHHHHHHHHHHHHHTTTTSGGGHHHHHHHHHHHHS?GGGHHHHHHHHHTTT??HHHHHHHHHHHHHHTTS?EEEEEETT-EEEEE?S?HHHHHHHHHHHHHHHHHHHHHHHT?GGGHHHHHHHHHHHHHHHHSS??GGGGHHHHHHHHHHHTTSSSSS??SGGG??TTSTTT?SSSSSSHHHHHHHHHH??S??SS?HHHH?HHHHHHHTTSHHHH?HHHHHHHHHHHHTTT 1HBN|B PF02244.11_Propep_M14_seed 103 84 !Q:3,5|7,7|22,23|27,28|33,39|44,44|50,50|66,66|74,74 Q:0,2|6,6|8,21|24,26|29,32|40,43|45,49|51,65|67,73|75,83 EEE---E?SSHHHHHHHHTTTS-?GGG??EEEE???----STTS?EEEEE?HHHHHHHHHHHHHTT?EEEEEES?HHHHHHHHH 1PCA|A PF02245.11_Pur_DNA_glyco_seed 149 358 !Q:0,0|3,5|8,9|22,22|28,28|31,34|36,36|41,48|57,63|66,66|75,77|79,87|95,95|115,115|120,123|135,136|140,143|146,166|172,187|189,221|238,239|242,242|246,246|251,258|261,283|287,296|298,299|301,322|327,327|332,332|334,341|349,349|355,355 Q:1,2|6,7|10,21|23,27|29,30|35,35|37,40|49,56|64,65|67,74|78,78|88,94|96,114|116,119|124,134|137,139|144,145|167,171|188,188|222,237|240,241|243,245|247,250|259,260|284,286|297,297|300,300|323,326|328,331|333,333|342,348|350,354|356,357 ?HH---HH-?SBHHHHHHHTTT?EEEEE?TT----S?EEEE--------EEEEEEEE??-----TT?TTSTTGGG???S---------SSGGGGS?TTBEEEEEETTTEEEEEEE?BSTT?---EEEEEEEEEEE-?HHH----HH---------------------HHHHT----------------S???-----------------------???????GGGTSSSHHHHHHHTT??GG-GTT?BTTT-------?SS-----------------------EEE----------E??S--------???----------?GGGE-EEEE?S????-???TTTSEEE-EEETT?TT 3QI5|A PF02246.10_B1_seed 3 70 !Q:0,1|4,7|20,20|49,50|67,69 Q:2,3|8,19|21,48|51,66 ??SS????EEEEEEEEETTS?EEEEEEEESHHHHHHHHHHHHHHHHHHH??EEEEEEGGGTEEEEEE??? 1K53|A PF02247.11_Como_LCP_seed 10 381 !Q:0,3|9,18|32,32|35,36|54,55|64,64|66,66|68,68|70,70|77,80|83,85|96,96|99,102|116,116|120,120|122,122|128,128|130,130|135,135|137,137|146,146|148,149|157,158|161,162|165,165|175,175|178,183|189,190|205,205|209,212|218,219|222,222|231,232|255,255|257,257|262,263|270,270|274,274|277,277|280,282|292,294|297,298|301,301|306,306|310,310|313,313|317,319|322,323|327,328|330,330|338,338|340,340|343,343|347,348|363,370|372,380 Q:4,8|19,31|33,34|37,53|56,63|65,65|67,67|69,69|71,76|81,82|86,95|97,98|103,115|117,119|121,121|123,127|129,129|131,134|136,136|138,145|147,147|150,156|159,160|163,164|166,174|176,177|184,188|191,204|206,208|213,217|220,221|223,230|233,254|256,256|258,261|264,269|271,273|275,276|278,279|283,291|295,296|299,300|302,305|307,309|311,312|314,316|320,321|324,326|329,329|331,337|339,339|341,342|344,346|349,362|371,371 ????STTSS??????????TTTTEEEEEEEEE?TT??SSEEEEEEEHHHHHSSS??TTHHHHHS?S?B?S?EEEEEE????TT???EEEEEEESEE?SS-???SSSTTSSSEEEEE?TTT?S?EEEEE?S?TTSS?B?HHHHHTTT?E--EEEEEEE??SS??SS?EEEEEEEEE?SS??????EESSS??TTEEEEEEEEEEEE?SBS????EEEES??SS?EEETTEEE??HHHHTGGGSSEEEEEEEEEEEE?S?TTSB??EEEEEE?TTS?TT?GG---GGGSSEEEE???TT??EE-EEEE?GGG?SS?EES???TT??TTT??S?EEEEEES-S?BB?SSS??EEEEEEEEEEEEEE????????S????????? 1BMV|2 PF02248.11_Como_SCP_seed 10 185 !Q:0,3|6,7|15,16|18,20|24,24|40,41|45,47|52,54|65,65|78,79|83,83|87,90|100,100|104,105|112,113|126,127|132,132|134,134|137,137|142,145|158,158|167,167|170,170|173,173|178,180|183,184 Q:4,5|8,14|17,17|21,23|25,39|42,44|48,51|55,64|66,77|80,82|84,86|91,99|101,103|106,111|114,125|128,131|133,133|135,136|138,141|146,157|159,166|168,169|171,172|174,177|181,182 ????TT??EEEEEEE??S???SSS?SEEEEEEETTTTEEE??SSS-??EEEE???HHHHHHHHBS?EEEEEEEEEEEE??SSS?GGG????EEEEEESSS?SSS??SEEEEE??SSEEEEEEEEEE??SSSS?B?TT?TTTT????EEEEEEESTTTS?EEEEEEEE?TT?EE?SBEE???EE?? 1BMV|1 PF02249.12_MCR_alpha_seed 22 142 !Q:10,10|13,14|34,37|48,50|52,52|57,57|61,66|88,88|96,96|119,119|140,141 Q:0,9|11,12|15,33|38,47|51,51|53,56|58,60|67,87|89,95|97,118|120,139 HHTIIIIITS?TT??HHHHHTTTBTTHHHHHHHH----HHHHHHHHTT---S-TTSS?SSS????-?HHHHHHHHHHHHHHHHHHHHH?HHHHHHT?SHHHHHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHT?? 1HBN|A PF02250.10_Orthopox_35kD_seed 5 279 !Q:1,4|9,9|19,19|22,22|26,33|42,45|51,55|60,82|102,106|123,125|128,128|132,135|143,143|149,149|158,175|177,187|189,190|193,210|235,237|239,240|244,244|258,267|271,271|275,275 Q:0,0|5,8|10,18|20,21|23,25|34,41|46,50|56,59|83,101|107,122|126,127|129,131|136,142|144,148|150,157|176,176|188,188|191,192|211,234|238,238|241,243|245,257|268,270|272,274|276,278 S????TTEE?EEEEEEEEE-EE?TTS????????EEEEEETT---?STTEE-----EEES??---------------------EEEEEEEETTEEEEEEEES?????EEEEEEETTEEEEEEE???TT-SSS????EEHHHHH-HHHHH?EEEEEEEE???????----------?B???????????S??EE---------------???EEEEEEETTTEEEEEEEEEEEESS---S??GGG?EEEEEEEETTEEE----??????TSS?GGG?EEB 1CQ3|A PF02251.13_PA28_alpha_seed 18 72 !Q:0,1|7,7|13,16|43,43|50,51|53,53|58,71 Q:2,6|8,12|17,42|44,49|52,52|54,57 ??HHHHH-HHHHH----HHHHHHHHHHHHHTHHHHHHHHHHHH-HHSGGG??S?TTSS???--???------ 1AVO|A PF02252.13_PA28_beta_seed 16 154 !Q:0,5|7,9|41,45|48,49|93,93|141,141|143,153 Q:6,6|10,40|46,47|50,92|94,140|142,142 -----?B???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?????SS??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?TTBTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHH?S??--------- 1AVO|B PF02253.10_PLA1_seed 78 327 !Q:0,2|5,5|11,22|26,26|28,29|33,33|38,38|40,42|50,57|63,66|81,81|89,93|108,109|111,111|113,113|117,118|136,140|142,142|146,149|160,162|168,171|175,178|192,196|198,198|201,202|214,228|230,230|240,240|252,252|265,267|283,290|294,294|305,305|313,314|316,316|326,326 Q:3,4|6,10|23,25|27,27|30,32|34,37|39,39|43,49|58,62|67,80|82,88|94,107|110,110|112,112|114,116|119,135|141,141|143,145|150,159|163,167|172,174|179,191|197,197|199,200|203,213|229,229|231,239|241,251|253,264|268,282|291,293|295,304|306,312|315,315|317,325 ???TT?HHHHH????---?????BEE?S??EEE-EEEE-S???TTTTTTS--------GGGGG--??SEEEEEEEEEEEEE-EETTTST-----TEEEEEEEEEEEEE??S?G-GGT??EEEEEEEEEEEEEEEEE-----E-EET----TEEEEEEEEE---EEEEE????TTT--??EEEEEEEEEEEEE-----T-TE--EEEEEEEEEES?-------------?T-TSTTHHHHH?SEEEEEEEEET-TEEEEEEEEEET---TTTEEEEEEEEEEES--------SSS?EEEEEEEEES?SSSTTTT??E-EEEEEEEES? 1QD6|C PF02254.13_TrkA_N_seed 219 195 !Q:4,6|22,41|49,49|51,52|55,56|61,62|64,64|67,69|73,80|84,84|86,86|97,97|102,102|104,105|110,114|116,123|125,128|139,139|142,144|147,152|155,156|159,159|165,169|174,174|177,178|181,188|193,193|195,195 Q:0,3|7,21|42,48|50,50|53,54|57,60|63,63|65,66|70,72|81,83|85,85|87,96|98,101|103,103|106,109|115,115|124,124|129,138|140,141|145,146|153,154|157,158|160,164|170,173|175,176|179,180|189,192|194,194 EEEE?-?SHHHHHHHHHHHHTT-?------------------EEEEEES?H--HH--HHHH--H-HH?--SSE--------EEE-S?TTSHHHHHHT-TTTT?S--EEEE?---?S-------?H----HHHHHHHHHH-HH---TT???---EE--EE?SSTTH-----HHHH-HH--TT-----?--SEEE?H- 1ID1|A PF02255.11_PTS_IIA_seed 110 102 !Q:28,28|61,68|93,96 Q:0,27|29,60|69,92|97,101 THHHHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT--??????HHHHHHHHHHHHHHHHHHHHHHHH----HHHHH 3K1S|A PF02256.12_Fe_hyd_SSU_seed 109 72 !Q:0,0|2,2|6,6|16,16|22,22|24,26|28,29|33,33|41,41|46,50|54,54|64,68|71,71 Q:1,1|3,5|7,15|17,21|23,23|27,27|30,32|34,40|42,45|51,53|55,63|69,70 ?S?TTH-HHHHHHTSS?HHHHT-S---B??GGG?HHHHHHH-HHTT?----STT-SHHHHHHHB??-??TT? 3C8Y|A PF02257.10_RFX_DNA_binding_seed 34 147 !Q:0,8|18,18|22,22|30,52|67,72|87,87|95,120|123,124|127,130|134,138|143,147 Q:9,17|19,21|23,29|53,66|73,86|88,94|121,122|125,126|131,133|139,142 --------?HHHHHHHEE-EEE-EEEEEHH-----------------------HHHHHHHHHHHHTT-?????HHHHHHHHHHHSTT?EEEEESS--------------------------TT??EE----EEE-----EEEE??--- 1DP7|P PF02258.11_SLT_beta_seed 2 70 !Q:0,3|8,9|11,11|14,15|19,20|31,32|35,35|47,47|49,49|56,56|61,63|68,69 Q:4,7|10,10|12,13|16,18|21,30|33,34|36,46|48,48|50,55|57,60|64,67 -???EEEE??S?EE??SSS??EEEETTEEEE??SS?HHHHHHHHHHH?S?EEEESS?SSSS???SEEE?? 2BOS|A PF02259.18_FAT_seed 55 626 !Q:12,13|17,18|27,52|57,64|68,70|79,80|84,84|87,89|109,111|113,113|115,117|129,137|150,150|153,166|171,174|185,189|204,266|286,286|301,301|309,327|345,352|354,364|372,372|378,378|388,389|392,392|396,434|444,445|459,472|474,474|497,497|500,500|526,579|610,614|616,616 Q:0,11|14,16|19,26|53,56|65,67|71,78|81,83|85,86|90,108|112,112|114,114|118,128|138,149|151,152|167,170|175,184|190,203|267,285|287,300|302,308|328,344|353,353|365,371|373,377|379,387|390,391|393,395|435,443|446,458|473,473|475,496|498,499|501,525|580,609|615,615|617,625 HHHHHHHHHHTS?-HHH--HHHHHTTS?-------------------------TTSH--------HHH---HHHHHHHH--HHT?HH---HHHHHHHHHHHHHHHHHHH---T?S???TTTTSHHHHHH---------HHHHHHHHHHTS-SS-----------???TTHH----HHHHHHHHHS?-???HHHHHHHHHHHTTT??-------------------------------------------------------------HHHHTHHHHHHHHHHHHTT?HHHHHHHHHHHHTS?SSSSTTS??---------------??SSHHHHHHHHHHHHHSS-------?H-----------HHHHHHH-HHHHH-HHHHHHHTT??SS?SHH---------------------------------------HHHHHHHHH--HHHHHHHHHHHHH--------------H?SSTTHHHHHHHHHHHHHHHHSS?HH-HHHHHHHHHHHHHHHHHHHHHHHTT??????????????????????????????????????????????????????HHHHHHHHHHHHHHHHHHHHHHHHHTTTSS-----S?HHHHHHHHH 4JSP|A PF02260.15_FATC_seed 141 36 !Q:0,2|4,5|29,29|32,32|34,35 Q:3,3|6,28|30,31|33,33 ?-?S-?STHHHHHHHHHHHHHHHHHHHHT-SS?S?? 4JSP|A PF02261.11_Asp_decarbox_seed 163 119 !Q:0,0|4,6|14,16|22,23|37,38|41,42|51,52|57,57|62,62|67,67|79,79|82,82|89,90|98,98|101,104|109,111|114,118 Q:1,3|7,13|17,21|24,36|39,40|43,50|53,56|58,61|63,66|68,78|80,81|83,88|91,97|99,100|105,108|112,113 ?EEE???EEEEEEE???EESSS??EEEEEHHHHHHTT??SS??EEEEETTT??EEEE?EEEE?TTTT?EEEESSTTTTS?TT?EEEEEE??EEEHHHH-HS-???EEEE??-TT????? 4AOK|A PF02262.11_Cbl_N_seed 3 130 !Q:0,6|25,25|29,31|33,33|36,36|58,58|65,65|98,98|126,128 Q:7,24|26,28|32,32|34,35|37,57|59,64|66,97|99,125|129,129 ???????HHHHHHHHHHHHHHHHHT?TTT???S?SS?HHHHHHHHHHHHHHHHHHSTT?HHHHHH?HHHHHHHHHHHHHHHHHHHHHHHHGGGGGSTT?HHHHHHHHHHHHHHHHHHHHHHHSGGG???G 3OP0|A PF02263.14_GBP_seed 13 302 !Q:6,6|14,17|20,21|23,23|47,74|79,82|86,89|98,102|108,108|116,117|119,120|124,125|140,140|151,152|172,191|193,193|202,203|206,206|213,214|224,226|229,229|247,247|255,257|259,260|263,265|271,272|277,277|294,294|296,299|301,301 Q:0,5|7,13|18,19|22,22|24,46|75,78|83,85|90,97|103,107|109,115|118,118|121,123|126,139|141,150|153,171|192,192|194,201|204,205|207,212|215,223|227,228|230,246|248,254|258,258|261,262|266,270|273,276|278,293|295,295|300,300 TTEEEE?HHHHHHH----HH??S?EEEEEEEEBSSSSHHHHHHHHTT---------------------------?SSSS????BSS????SEEEEEEE----?SSSTT?EEEEEEE??B??TTT??HHHHHHHHHHHHHH?SEEEEEEESS??HHHHHHHHHHHHHHHHHHH????????????????????S?EEEEEEES??SB?EETTEE??HHHHHHHHT???SS?SHHHHHHHHHHHHHHHH?SSEEEEE???S??SS??-TTGGG??GGGS?HHHHHHHHHHHHHHHH-H????B? 4IDN|A PF02264.10_LamB_seed 6 490 !Q:17,22|25,25|27,35|38,40|71,74|79,102|104,106|113,115|121,122|128,128|136,137|139,140|152,154|157,157|166,166|230,235|238,238|240,242|245,247|264,264|281,281|284,286|291,292|296,304|308,314|343,343|348,354|357,366|401,406|411,412|429,432|447,447|469,469|471,474|489,489 Q:0,16|23,24|26,26|36,37|41,70|75,78|103,103|107,112|116,120|123,127|129,135|138,138|141,151|155,156|158,165|167,229|236,237|239,239|243,244|248,263|265,280|282,283|287,290|293,295|305,307|315,342|344,347|355,356|367,400|407,410|413,428|433,446|448,468|470,470|475,488 EEEEEEEEEEEETTSSB??????TT?S-----????TT???SEEEEEEEEEEEEEETTEEEEEEEEEEEEE--??SSSS?-----------------------B???EEEEEE---EEEET??TTSTT?EEEEEEE??S?-EEEGGGTEEEE???EE-EEEEEEEE?SSSEEEEEEEEEEEEEEEEEEEETTEEEEEEEEEEEEEEEEEEEEEEETTEEEEEEEEEEEEE----??TT?B??-TT???EEEEEEEEEEEEETTE-EEEEEEEEEEGGGTTT?SS???TTTT??EEE?????????EEE???????EEEEEEEEEEEEEETTTEEEEEEEEEEE-EEET-------TS??--------EEEEEEEEEEEEEEETTEEEEEEEEEEEEEETTT?----?EEEE--EEEEEEEEEESSSSTT?--?SEEEEEEEEEEEEE?EEEEEETTEEEEEEEETTSSS?B????EEEEEEEEEEEEEE? 1MPN|A PF02265.11_S1-P1_nuclease_seed 81 395 !Q:0,1|16,18|30,31|33,40|43,43|46,46|60,62|64,65|67,83|89,92|95,95|99,100|103,109|111,116|121,121|123,124|127,129|132,132|134,134|149,165|186,186|190,195|204,204|210,215|219,223|225,232|244,245|255,262|264,264|279,279|290,297|301,323|337,338|343,347|350,351|354,354|356,358|360,360|362,363|365,365|394,395 Q:2,15|19,29|32,32|41,42|44,45|47,59|63,63|66,66|84,88|93,94|96,98|101,102|110,110|117,120|122,122|125,126|130,131|133,133|135,148|166,185|187,189|196,203|205,209|216,218|224,224|233,243|246,254|263,263|265,278|280,289|298,300|324,336|339,342|348,349|352,353|355,355|359,359|361,361|364,364|366,393 ??HHHHHHHHHHHHTT?-?HHHHHHHHHHS-?G--------GG-TT?GGGGTTGGGGGTT---T--T-----------------GGGGG----GG?EEE-?SS-------S???---HHHH?B?-TT-??BT?S-HHHHHHHHHHHHTT???????????-----?HHHHHHHHHHHHHHTTSGGG-EEE------GGGTTTTT?EEEET------TEE-----E--------EHHHHHHTHHH--HHHHHHTTT--------T?HHHHHHHHHHHHHH-TSHHHHHHHH??-----?SSS---?------------------?HHHHHHHHHHHHH--HTTS-----TT??TT?E---E?H--H-HHHHHHHHHHHHHHHHHHHHHHHHHHHH?- 3SNG|A PF02267.12_Rib_hydrolayse_seed 12 318 !Q:0,0|16,21|24,24|27,41|45,46|62,62|65,67|79,85|95,95|97,98|107,107|112,112|114,114|127,136|139,144|148,152|157,160|162,164|182,209|222,223|226,231|233,233|247,247|260,261|264,268|271,273|292,292|300,301|311,317 Q:1,15|22,23|25,26|42,44|47,61|63,64|68,78|86,94|96,96|99,106|108,111|113,113|115,126|137,138|145,147|153,156|161,161|165,181|210,221|224,225|232,232|234,246|248,259|262,263|269,270|274,291|293,299|302,310 ?TTHHHHHHHHHHHHH------HH?GG---------------GTT??HHHHHHHHHHHHTTS?TT???HHHHHHHHHHT???--??GGGBEEEES?H--HHHHHHHH-HSTT?B?GGGSHHHHHHTT??????----TT??????SEE---??TTTT---?S?--SHHHHHHHHHHHHHHHH??--------------------------EEEEEEEETTST--TS------S?SSSHHHHTTGGGS?TTTEEEEEEEEE??SS-----SS???GGGSHHHHHHHHHHHHTT?EEEEEEE??HHHHHHHHH??????? 3ROK|A PF02268.11_TFIIA_gamma_N_seed 21 52 !Q:0,3|10,12|31,31 Q:4,9|13,30|32,51 ????GGGGSH---HHHHHHHHHHHHHHTTSS?HHHHHHHHHHHHHHHHHHHH 1NH2|D PF02269.11_TFIID-18kDa_seed 6 93 !Q:0,2|16,16|19,20|45,92 Q:3,15|17,18|21,44 -??TTTTHHHHHTTTS?SS??HHHHHHHHHHHHHHHHHHHHHHHT?----------------------------------------------- 1BH8|A PF02270.10_TFIIF_beta_seed 25 365 !Q:5,5|10,11|14,14|30,37|40,41|44,48|59,64|75,75|81,83|86,97|101,101|103,104|112,113|115,121|134,207|221,364 Q:0,4|6,9|12,13|15,29|38,39|42,43|49,58|65,74|76,80|84,85|98,100|102,102|105,111|114,114|122,133|208,220 TTBEE?HHHH--TT?EEEEEEEEHHHHHHH--------TT??TT----?EEEEEEEEEE------TTEEEEEEEE?HHHHT???TT---------???STT?S??EEEEEEE??T-------TSEEEEEEEETT------------------------------------------------------------------------??EEEEEEEEEEEEE???--------------------------------------------------------------------------------------------------------------------------------------------- 1BBY|A PF02271.11_UCR_14kD_seed 25 110 !Q:3,3|20,21|24,24|30,31|37,42|54,54|76,79|84,85|89,91 Q:0,2|4,19|22,23|25,29|32,36|43,53|55,75|80,83|86,88|92,109 HHH?HHHHHHHHHHHHHHHH--HH?GGGGT??GGGGS??---?SHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHTT????GGGS??TTT???SSHHHHHHHHHHHHHHHH 1SQB|F PF02272.14_DHHA1_seed 133 92 !Q:8,12|25,25|32,34|36,36|51,55|58,58|68,68|72,81 Q:0,7|13,24|26,31|35,35|37,50|56,57|59,67|69,71|82,91 SEEEEEEE-----EETTEEEEEEEE?GGGTTT---S?HHHHHHHHHHHTTB---??EE?SSEEEEEES?GGG----------HHHHHHHHHH 2ZXR|A PF02273.10_Acyl_transf_2_seed 4 295 !Q:1,1|20,22|26,28|30,30|36,36|39,39|57,58|63,65|67,79|96,96|100,102|123,124|132,133|135,135|147,147|152,152|156,157|181,181|194,195|197,197|206,206|210,210|221,221|224,225|234,235|237,237|263,274|295,295 Q:0,0|2,19|23,25|29,29|31,35|37,38|40,56|59,62|66,66|80,95|97,99|103,122|125,131|134,134|136,146|148,151|153,155|158,180|182,193|196,196|198,205|207,209|211,220|222,223|226,233|236,236|238,262|275,294 S?EEEEEEETTTEEEEEEEE???TTS???S?EEEEE?TT?GGGGGGHHHHHHHHTTT??EEEE???B?????????????HHHHHHHHHHHHHHHH-HTT???EEEEEETHHHHHHHHHTTTS??SEEEEES??S?HHHHHHHHHSS?GGGS?GGG??SEEEETTEEEEHHHHHHHHHHTT?SSHHHHHHHHTT??S?EEEEEETT?TTS?HHHHHHHHTT?TT??EEEEEETT??S?TTSSHHHHHHHHHHHHHHHHHHHTT????????????HHHHHHHHHHHHHHHHHGGG- 1THT|A PF02274.12_Amidinotransf_seed 55 461 !Q:1,5|11,12|21,33|35,38|57,57|59,59|87,87|92,92|107,107|109,112|122,122|129,129|131,131|145,148|152,154|159,159|167,171|173,174|180,182|201,201|208,209|214,215|217,217|220,221|224,227|229,229|247,247|250,250|265,266|269,269|277,285|301,301|306,306|309,309|317,317|320,322|332,332|335,335|344,350|353,353|355,357|360,360|363,365|367,373|376,383|387,391|397,403|409,409|420,431|433,433|439,440|445,445|449,450|455,455 Q:0,0|6,10|13,20|34,34|39,56|58,58|60,86|88,91|93,106|108,108|113,121|123,128|130,130|132,144|149,151|155,158|160,166|172,172|175,179|183,200|202,207|210,213|216,216|218,219|222,223|228,228|230,246|248,249|251,264|267,268|270,276|286,300|302,305|307,308|310,316|318,319|323,331|333,334|336,343|351,352|354,354|358,359|361,362|366,366|374,375|384,386|392,396|404,408|410,419|432,432|434,438|441,444|446,448|451,454|456,460 E??-??HHHHT??TTTTGGGT?------------S????HHHHHHHHHHHHHHHHTT-T?EEEEHHHHHHHHTTSHHHHHHHHHHHS?HHHH?TTTHHHHHHHHHTS?H----HHHHHHHHH?EEGGGS?S?HHHHHHHHHHHHS????EEE???GGGG?TTTTEEE----?S--SEEEE???SSGGGHHHHHHHHHHHHH?HHHHTS??EEEE??T-TS??TT????G-GGEEEEETTEEEEEESS-SS?HHHHHHHHHHHHHT--TS?SEEEEEE?????????HHHHEEEEETTEEEE?HHHH-TT?EEEEEEE?TT---STTSEEEEE?SS?HHHHHHHH-------TT?S?-?EE-EE???S?-?????SS?-??????EEE-----ETTEE-------EEETT?HHHHHHHHHT------------T?EEEEE??TTTT-SSS??TTTT?EEEEE 2CI1|A PF02275.13_CBAH_seed 8 370 !Q:0,0|7,7|11,11|22,27|29,32|36,38|41,41|44,44|48,49|53,54|58,58|61,75|79,79|89,89|100,100|107,109|113,115|119,120|139,139|156,162|167,173|180,180|184,184|189,189|192,192|195,196|202,204|209,209|213,213|215,215|220,221|230,231|234,236|247,247|251,251|257,259|261,261|285,286|298,300|306,306|310,310|312,312|334,335|337,337|346,346|348,361|363,363|366,366 Q:1,6|8,10|12,21|28,28|33,35|39,40|42,43|45,47|50,52|55,57|59,60|76,78|80,88|90,99|101,106|110,112|116,118|121,138|140,155|163,166|174,179|181,183|185,188|190,191|193,194|197,201|205,208|210,212|214,214|216,219|222,229|232,233|237,246|248,250|252,256|260,260|262,284|287,297|301,305|307,309|311,311|313,333|336,336|338,345|347,347|362,362|364,365|367,369 ?EEEEEE?TTS?EEEEEEEEES------S????EEE---EE?TT?EEE?-SSS??EEE?SS--------------?EEE-EEEEETTEE-EEEEEEETTS?EEEEEE?--TTT???BSS??TTSEEEEGGGHHHHHHHH?SSHHHHHHHHTTEEEE?----??SSTT??--???EEEEEE?TTS?EEEE-EE?SS-?EEEEE?-?SSEE?SSS?H-HHHH--HHHGGGTT??SS???EEEETTEEEE?SSS?GGGTT???S?SHHHHHHHHHHHHHHHHHHHGGG??HHHHHHHHHTT???TTTSB?TTS?B?EEEEEEEEETTTTEEEEEESS??S?EEEEGGGS?T--------------T?SS?EEE 2RF8|A PF02276.13_CytoC_RC_seed 25 368 !Q:0,3|5,7|10,12|18,19|21,21|24,24|35,35|40,51|62,62|64,64|86,87|91,91|99,99|101,102|106,108|129,129|132,132|135,137|141,143|154,154|157,157|159,159|162,163|171,173|180,180|183,189|202,207|214,216|220,225|227,236|238,238|243,243|254,256|276,277|283,283|289,290|295,295|320,320|325,325|330,330|333,333|335,337|339,340|355,357|361,361|366,367 Q:4,4|8,9|13,17|20,20|22,23|25,34|36,39|52,61|63,63|65,85|88,90|92,98|100,100|103,105|109,128|130,131|133,134|138,140|144,153|155,156|158,158|160,161|164,170|174,179|181,182|190,201|208,213|217,219|226,226|237,237|239,242|244,253|257,275|278,282|284,288|291,294|296,319|321,324|326,329|331,332|334,334|338,338|341,354|358,360|362,365 ????S-??EE???SSTTS??S?EE?HHHHHHHHHH-HTTS?????????--?SSBHHHHSSS?S-SSTTSBHHHHHHHHHHHHHHT?-TTT?GGGTSBT-T--BTT???SHHHHHHHHHHHHHHHHHHH?HH-HH---TTT???HHHHHTTSSS?SS?B?SS??SSSSTTS???TTTSTT?GG-------GHHHHHHTTTTT??????HHHHHT---SSS-----?S??------??S?SSSS?BTTTSSGGGS??-THHHHHHHHHHHHHHHHHT??GGGTB?GGGTT??BTTB?HHHHHHHHHHHHHHHHHHHTTGGG-GGTS?GGGS?TT-S???B??HHHHHTTSSSGGGG???TTT?GGGS?? 3G7F|C PF02277.12_DBI_PRT_seed 26 393 !Q:4,8|42,46|53,63|66,66|74,74|82,84|86,86|100,105|107,107|119,119|122,123|125,128|134,134|137,140|142,143|149,151|156,157|162,162|165,167|198,198|200,200|202,202|218,219|224,226|228,228|231,232|237,246|259,259|262,264|266,268|270,270|273,273|280,281|299,300|303,304|318,318|320,320|329,330|332,333|347,349|352,362|384,385|392,392 Q:0,3|9,41|47,52|64,65|67,73|75,81|85,85|87,99|106,106|108,118|120,121|124,124|129,133|135,136|141,141|144,148|152,155|158,161|163,164|168,197|199,199|201,201|203,217|220,223|227,227|229,230|233,236|247,258|260,261|265,265|269,269|271,272|274,279|282,298|301,302|305,317|319,319|321,328|331,331|334,346|350,351|363,383|386,391 HHHT?????HHHHHHHHHHHHTBSSSTTTTTHHHHHHHHHHT?----GGGTTS-------????EE-EEEEEEE?BGGGGGT???S?TTHHHHHHHHHHH------T?SHHHHHHHHTT?EE--E----EEEEE?SS----S??TTSEE???SSSB??TTTS?SS--?HHHHHHHHHHHHHHHHHHHTTTEEEEEEEE-E?T-TTHHHHHHHHHHHHT??HHHH???T-TT??GGGH----------HHHHHHHHHHHH-HH???T---T?HH-HHHHHH??HHHHHHHHHHHHHHHTT??EE??SHHHHHHHHHHHH-H?GGGGGGEE??B??SSTTHHHHHHHTT???SB??----?????TTHHHHHHHHHHHHHHHHHHH??BHHHHT? 1L5L|A PF02278.13_Lyase_8_seed 5 295 !Q:0,5|31,33|39,41|46,46|49,49|61,63|65,65|78,78|82,82|85,85|89,97|114,115|117,118|120,120|122,122|141,141|146,146|168,168|172,172|174,174|184,185|189,190|199,201|205,207|219,219|224,225|246,246|254,259|271,272|275,276|278,279|288,289|295,295 Q:6,30|34,38|42,45|47,48|50,60|64,64|66,77|79,81|83,84|86,88|98,113|116,116|119,119|121,121|123,140|142,145|147,167|169,171|173,173|175,183|186,188|191,198|202,204|208,218|220,223|226,245|247,253|260,270|273,274|277,277|280,287|290,294 ??????EEEEEGGGTEEEEEETTTTEEEEEE???TTSBS???BTTB?TT?TTTTSSEEEEE?--S?TTTTSSSHHHHS?SSS?TT?EEE???????-?TTTTTTSTTSTTTTTT??B?-S?S?EEEEESSSSEEEEEEEEE?TTSS?EEEEEEEEETTEEEEEEEEEE?SSS?S?EEEEEEEEE??SSS??EEEETTEE???SSS???EEEEEEEEEEE?SSTT??EEEEEEEEEEEEEEEEEEEE?HHHHBTT??????EEEEEEEEEEE??SS--S??EEEEEEES??HHHHH- 2E24|A PF02281.11_Dimer_Tnp_Tn5_seed 2 109 !Q:3,23|30,30|45,46|50,50|67,69|73,77|106,108 Q:0,2|24,29|31,44|47,49|51,66|70,72|78,105 HHH?????????????????????BGGGTS?HHHHHHHHHHHTTT??TTS?TTBHHHHHHHHHHHTT???TTS?????HHHHHHHHHHHHHHHHHHHHHHHHHHTT??? 1MUS|A PF02282.11_Herpes_UL42_seed 12 170 !Q:26,26|60,65|68,68|90,91|96,107|116,116|120,120|133,146|149,149|154,155|161,162|165,165 Q:0,25|27,59|66,67|69,89|92,95|108,115|117,119|121,132|147,148|150,153|156,160|163,164|166,169 EEEEEEHHHHHHHHHHHGGGTTTTSS?EEEEETTEEEEEEEETTEEEEEEEEGGGSSEEE??----SS?EEEESEEETTEETTSTTSTTT?-TTEE------------EEEEEEES?TTS?EEEEEEEETTSS--------------TT?SSSS??EEEEE??SS?EEEE 1DML|A PF02283.11_CobU_seed 192 239 !Q:5,5|19,24|26,31|35,35|40,58|68,71|78,83|85,86|88,91|95,95|98,100|102,102|105,109|112,112|118,118|130,135|139,151|158,160|174,176|179,181|188,192|195,197|220,220|233,236|238,238 Q:0,4|6,18|25,25|32,34|36,39|59,67|72,77|84,84|87,87|92,94|96,97|101,101|103,104|110,111|113,117|119,129|136,138|152,157|161,173|177,178|182,187|193,194|198,219|221,232|237,237 EEEEE?TTSSHHHHHHHHH-----?S?-----SSE-EEEE?????----??----????HHHHHHHTS---?TTEEEE??----S--S---?GGG-TS--?T-TS?----TT?EEEEE?HHHHHHHHHHH??????TTS?-----------?HHHHHH---HHHHHHHHHHHHH---HH-??SEEEEE?????SS???SSHHHHHHHHHHHHHHHHHHHH?SEEEEEETTEEE----E? 1C9K|A PF02284.11_COX5A_seed 3 109 !Q:0,6|20,20|23,24|41,43|59,59|77,77|80,80|98,100|108,108 Q:7,19|21,22|25,40|44,58|60,76|78,79|81,97|101,107 ???????HHHHHHHHHHHHH?TT??HHHHHHHHHHHTTSSB???HHHHHHHHHHHHHTT?HHHHHHHHHHHHHHTTT?TT-HHHHHHHHHHHHHHHHT???TTTTTTT? 1V55|E PF02285.10_COX8_seed 11 44 !Q:0,0|3,5|8,10|42,43 Q:1,2|6,7|11,41 ?EE???SS???HHHHHHHHHHHHHHHHHHHHHHHHTHHHHHT?? 1V55|M PF02286.10_Dehydratase_LU_seed 11 557 !Q:0,2|11,11|17,18|20,21|28,28|31,32|36,40|59,60|72,72|83,83|93,93|97,97|109,109|120,121|133,133|138,138|144,146|149,150|166,166|172,173|197,197|202,204|217,217|225,226|237,238|254,254|260,261|270,271|274,275|292,292|297,297|328,328|332,335|337,339|341,341|356,357|368,368|372,372|376,377|380,380|396,398|400,404|428,428|430,432|442,442|449,452|468,469|482,482|499,499|506,506|509,509|513,513|516,516|522,525|531,536|545,546|549,549|551,556 Q:3,10|12,16|19,19|22,27|29,30|33,35|41,58|61,71|73,82|84,92|94,96|98,108|110,119|122,132|134,137|139,143|147,148|151,165|167,171|174,196|198,201|205,216|218,224|227,236|239,253|255,259|262,269|272,273|276,291|293,296|298,327|329,331|336,336|340,340|342,355|358,367|369,371|373,375|378,379|381,395|399,399|405,427|429,429|433,441|443,448|453,467|470,481|483,498|500,505|507,508|510,512|514,515|517,521|526,530|537,544|547,548|550,550 ???HHHHHHHT?GGGGS??B??BGGGTB?SS??TTS????-EEEETTEEEEETTEEGGG??HHHHHHHHHTS?HHHHHHHTTS?HHHHHHHHH?TTS?HHHHHHHHTTS?HHHHHHHHTT??HHHHHHHHHHH?SBSS?EEEEE???TT??HHHHHHHHHHHHHHT?SEEEE??SSGGGHHHHHHHHHHHHHHHSTT?EEEE???HHHHHHHHHTTS?SEEEEEE??SSHHHHHHTT??HHHHHHHHHHHHTTT?EEEEE??TTHHHHTT??TT??HHHHHHHHHHHHHHHT?SEEE?SSGGGHHHHTTSTTHHHHHHHHHHHHHHTT?EEE????S???S?HHHHHHHHHHHHTT??TEEEEEEESS?GGG?TTS??SS?GGGHHHHHHHHHHHT???S?????HHHHHHHHHHHHHHHHHHHHHTT?S???HHHHHHHHH?SSGGGS????HHHHHHHHHHHHHHT??HHHHHHHHHTTT?HHHHHHHHHHHHHHHH?GGGSTT?EE?TTS?EE?TTTSB????STTSS???--?HHHHHHHH??TT?B?????? 1DIO|A PF02287.10_Dehydratase_SU_seed 17 138 !Q:0,6|10,10|16,16|20,20|26,26|31,32|42,42|46,47|49,49|65,65|82,82|98,99|115,116|135,135 Q:7,9|11,15|17,19|21,25|27,30|33,41|43,45|48,48|50,64|66,81|83,97|100,114|117,134|136,137 ????-??GGG?SHHHH?GGG?BBTTS?BGGG??HHHHHTTSS?TTT??B?HHHHHHHHHHHHHTT?HHHHHHHHHHHHHTTS?HHHHHHHHHHTSTTS??HHHHHHHHHHHHHTS??HHHHHHHHHHHHHHHHHT?ST 1DIO|G PF02288.10_Dehydratase_MU_seed 62 125 !Q:1,1|8,9|11,11|14,15|33,33|40,42|44,46|58,58|67,67|70,76|85,85|88,89|94,95|99,100|118,124 Q:0,0|2,7|10,10|12,13|16,32|34,39|43,43|47,57|59,66|68,69|77,84|86,87|90,93|96,98|101,117 E?TTTTTT??B?TT??BHHHHHHHHHHHHHTTT?EEEEEE-??S???HHHHHHHHHTT?TTSEEEEE?TT?-----?EEEEETTS?TT??SEEE??GGG??HHHHHHHHHHHHHHHTT??????? 1DIO|B PF02289.11_MCH_seed 6 322 !Q:0,0|21,21|26,26|30,30|40,42|57,57|61,62|94,95|100,101|105,106|131,135|137,137|144,144|147,149|163,163|173,173|200,202|215,219|237,237|244,246|248,250|270,270|281,281|286,286|292,292|303,304|310,312 Q:1,20|22,25|27,29|31,39|43,56|58,60|63,93|96,99|102,104|107,130|136,136|138,143|145,146|150,162|164,172|174,199|203,214|220,236|238,243|247,247|251,269|271,280|282,285|287,291|293,302|305,309|313,321 ?HHHHHHHHHHHHHHTHHHHT?EEEE?TTS?EEEESSSSS???HHHHHHHHHHHTTT?EEE--EEEEEEETTEEEEEEEEEESSHHHHHTTTTS??EEEE--ETT--EEEEEESTTHHHHTSSHHHHHHHT?????S?EEEEEE?SS???HHHHHHHHHHHTS?GGGEEEEEE?SSSHHHHHHHHTTHHHHHHHHHHHTS???GGGEEEEEEEEE?????SSHHHHHHHHHHHHHHH?EEEEEE???T---THHHHHHHSSGGGSTTTTS?HHHHHHHTTT?GGGS?GGGSS?SEEEEEETTT??EEEEE???HHHHHHHTT 4GVS|A PF02290.10_SRP14_seed 22 136 !Q:1,1|20,23|32,72|82,101|103,104|118,119|133,134 Q:0,0|2,19|24,31|73,81|102,102|105,117|120,132|135,135 E?HHHHHHHHHHHHHHTSSS?--?EEEEEEEE----------????-????????-----?????----????EEEEEEESS--------------------S?-EEEEEEETTSHHH--HHHHHHHHHHHHS??S 1RY1|D PF02291.10_TFIID-31kDa_seed 5 134 !Q:0,11|26,28|30,30|61,61|65,70|82,133 Q:12,25|29,29|31,60|62,64|71,81 -----------?HHHHHHHHHHHHTT???B?THHHHHHHHHHHHHHHHHHHHHHHHHHHTT?SSB?-----HHHHHHHHHHT??-------------------------------------------------- 1TAF|A PF02293.10_AmiS_UreI_seed 24 197 !Q:0,0|2,2|23,25|54,55|57,74|99,101|127,133|135,135|139,139|141,141|164,169|196,196 Q:1,1|3,22|26,53|56,56|75,98|102,126|134,134|136,138|140,140|142,163|170,195 ?H-HHHHHHHHHHHHHHHHHHHT???HHHHHHHHHHHHHHHHHHHHHHHHHHHH??S??????????????????THHHHHHHHHHHHHHHHHHHHHHT?-?HHHHHHHHHHHHHHHHHHHHHHHTS???????S?SSS?S?THHHHHHHHHHHHHHHHHHHHT??-???TTHHHHHHHHHHTTTHHHHHTTTTSS? 3UX4|A PF02294.13_7kD_DNA_binding_seed 2 62 !Q:0,1|14,14|18,20|23,23|31,33|39,42|45,45 Q:2,13|15,17|21,22|24,30|34,38|43,44|46,61 ??EEEEETTEEEEE?GGG???EE?SSSSEEE???SSSSS????EE?TTTSSSSSHHHHHHTT 1SAP|A PF02295.12_z-alpha_seed 8 67 !Q:16,16|19,20|22,22|32,33|54,54|58,58|63,66 Q:0,15|17,18|21,21|23,31|34,53|55,57|59,62 HHHHHHHHHHHHHHHH?TT??B?HHHHHHHHT??HHHHHHHHHHHHHTTSEEEE?SSS?EEEE???? 1SFU|A PF02296.11_Alpha_adaptin_C_seed 21 126 !Q:4,8|19,21|32,42|45,47|56,56|64,65|82,82|84,84|86,86|88,90|101,101 Q:0,3|9,18|22,31|43,44|48,55|57,63|66,81|83,83|85,85|87,87|91,100|102,125 GEEE???-?HHHHHHHHTT???GGGEEEEEEE----------?SS???HHHHHHHH-HHHTSEE??SSSSSTTSEEEEEEEE?S-S?E---EEEEEEEEEE-TTTTEEEEEEEESSHHHHHHHHHH 1KYD|A PF02297.12_COX6B_seed 58 117 !Q:3,3|5,13|16,16|39,63|67,81|94,94|105,109|114,116 Q:0,2|4,4|14,15|17,38|64,66|82,93|95,104|110,113 TTS?S---------SB?HHHHHHHHHHHHHHHHHHHHTT?-----------------------?GGG---------------SHHHHHHHHHHS?HHHHHHHHHH-----HHHT??? 1V55|H PF02298.12_Cu_bind_like_seed 26 106 !Q:1,2|5,10|19,19|21,21|24,24|30,31|35,36|41,42|50,51|54,55|60,73|81,82|91,92|95,96|101,102|105,105 Q:0,0|3,4|11,18|20,20|22,23|25,29|32,34|37,40|43,49|52,53|56,59|74,80|83,90|93,94|97,100|103,104 S??SS?---??HHHHHHTS?B?TT?EEEEE??TTT??EEEE?-HHHHHHT??SS-?SEEE?-------------SSEEEEE??SSEEEEEE??ST--TTGG--GT? 2CBP|A PF02300.12_Fumarate_red_C_seed 23 134 !Q:0,5|7,11|51,54|97,100|107,108|133,133 Q:6,6|12,50|55,96|101,106|109,132 ??????B?????TTGGGSSHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHT----HHHHHHHHHHHHTSSHHHHHHHHHHHHHHHHHHHHHHHGGGG?-??BSSSSB??SHHHHHHHHHHHHHHHHHHHHHHH? 1KF6|C PF02301.13_HORMA_seed 95 474 !Q:17,30|33,43|50,59|62,62|67,68|75,121|124,125|131,132|134,136|141,141|158,170|178,186|188,190|193,193|197,202|214,221|223,227|230,294|305,314|321,321|328,329|331,354|363,363|365,401|403,410|412,412|415,415|418,451|454,455|459,460|470,470 Q:0,16|31,32|44,49|60,61|63,66|69,74|122,123|126,130|133,133|137,140|142,157|171,177|187,187|191,192|194,196|203,213|222,222|228,229|295,304|315,320|322,327|330,330|355,362|364,364|402,402|411,411|413,414|416,417|452,453|456,458|461,469|471,473 SHHHHHHHHHHHHHHHH--------------HH-----------HHHHHT----------SS?GGGE--EEEEET-----------------------------------------------TE--EEEEE??H---HHHH-HHHHHHHHHHHTTTTT----------???EEEEEEE---------E---TT-TTE------EEEEEEEEEEE------??S?????SS----------?---------------------------------------------------???SHHHHHHHHH----------HHHHHH-HHHHHS--S??----------------??---?EEEEEEEE?S-------------------------------------S?---????S-SS?SB---------------------------------?TT??SSE--EEEEEEEEE?SSE 4GK0|A PF02302.12_PTS_IIB_seed 245 128 !Q:5,5|7,11|28,33|39,42|51,53|60,62|64,64|70,72|75,83|89,93|95,95|97,100|105,105|109,114|117,118|120,120 Q:0,4|6,6|12,27|34,38|43,50|54,59|63,63|65,69|73,74|84,88|94,94|96,96|101,104|106,108|115,116|119,119|121,127 EEEEE?S?????HHHHHHHHHHHHHHHT??----EEEEE----EETTEEES???HHHHHH-?-S?EEEEE---SS?--?---??GGGTT-----S-B----EEEE?HHH------HH--H?HHHHHHH 3CZC|A PF02303.12_Phage_DNA_bind_seed 3 89 !Q:0,1|3,3|5,8|13,16|18,19|21,22|26,32|34,35|38,38|42,42|45,46|48,50|53,57|60,60|62,62|64,64|67,70|75,78|80,85|87,88 Q:2,2|4,4|9,12|17,17|20,20|23,25|33,33|36,37|39,41|43,44|47,47|51,52|58,59|61,61|63,63|65,66|71,74|79,79|86,86 ??S?B????SSTT????S?-S??TTT???-???B??EE?SSS?EE??B???SS?????SS?B?S?SS????SSSS????S?-????B?? 1VQD|A PF02304.10_Phage_B_seed 6 117 !Q:0,57|78,80|90,91|94,95|97,98|102,107|115,116 Q:58,77|81,89|92,93|96,96|99,101|108,114 ??????????????????????????????????????????????????????????HHHHHHHHHHHHHHHHHHSS???HHHHHHHHH??TT??S??STT??????HHHHHTS?? 1CD3|B PF02305.12_Phage_F_seed 7 611 !Q:0,10|13,15|23,23|27,27|36,36|39,39|52,53|58,59|61,61|91,114|117,118|130,132|138,138|155,155|159,163|169,175|177,177|184,198|200,200|202,205|210,213|216,217|219,336|339,341|362,363|374,377|382,382|384,385|396,397|402,403|407,414|418,418|423,423|436,437|450,453|458,459|467,468|474,475|483,484|494,503|506,507|510,510|515,515|518,518|523,529|533,537|540,540|543,544|546,548|550,550|552,554|556,559|567,568|570,570|579,581|583,583|586,586|600,604|610,610 Q:11,12|16,22|24,26|28,35|37,38|40,51|54,57|60,60|62,90|115,116|119,129|133,137|139,154|156,158|164,168|176,176|178,183|199,199|201,201|206,209|214,215|218,218|337,338|342,361|364,373|378,381|383,383|386,395|398,401|404,406|415,417|419,422|424,435|438,449|454,457|460,466|469,473|476,482|485,493|504,505|508,509|511,514|516,517|519,522|530,532|538,539|541,542|545,545|549,549|551,551|555,555|560,566|569,569|571,578|582,582|584,585|587,599|605,609 ??????-????EE???EEEEEEE?SSB?EEEEEEEE?TT?EEEEEEEEEEEE??BSSS??S?EEEEEEEEEEESHHHHTHHHHHHHHHGGG?------------------?????EE??SSTTSSGGGSS???TTSEE?HHHHHHHHHHHHHHTS?TTS?????SSGGG-------S?TTTTTT?-------------?B?B????STTS???-TT??S??????---------------------------------------------------------------------------------------------------------------?SS???HHHHHHHHHHHHHHHHHHHT??SHHHHHHTTT????TTTT-T??EEEEEEEEEE??EEEE??STT--------TTT?EEEE?EEEEEEEEEEEE??SSEEEEEEEEEE????BTTB??HHHHSSS??HHHHS??HHHHTTS??EEEETTTTB----------SS??TT?EEEE?TT-GGGS???????TTT-----TT?TT??S---B?S???S----STGGGTB??G-GGGGGGBS---S?SS?SEEEEEEEEEEEE?????HHHHS? 2BPA|1 PF02306.10_Phage_G_seed 6 188 !Q:0,6|8,11|13,15|17,19|24,26|29,32|37,39|42,43|48,49|54,55|60,60|62,62|69,73|75,75|88,88|90,91|94,94|107,109|112,114|116,117|121,124|128,128|131,131|135,135|142,142|144,144|159,159|163,163|168,168|179,184|187,187 Q:7,7|12,12|16,16|20,23|27,28|33,36|40,41|44,47|50,53|56,59|61,61|63,68|74,74|76,87|89,89|92,93|95,106|110,111|115,115|118,120|125,127|129,130|132,134|136,141|143,143|145,158|160,162|164,167|169,178|185,186 ???????S????S-??B-??EEEE???SS-?--BBSS???SS--EEEE??EEEE??EESS?E-EEEEEE?????S?SEEEEEEEEEES-S??TT?EEEEEEEEEETT???SB??-S??EEE???-EEE?SS?EEE?EEEEEE?S?SSTTEEEEEEEEEE?SEE?SEEE?EEEEEEEESS??????TT? 2BPA|2 PF02310.14_B12-binding_seed 133 212 !Q:0,0|10,13|18,18|27,27|29,29|31,40|44,45|47,55|59,62|64,95|101,101|107,109|112,113|115,115|118,122|124,134|143,144|152,155|160,160|164,164|173,176|180,182|185,190|194,195|197,199|202,203 Q:1,9|14,17|19,26|28,28|30,30|41,43|46,46|56,58|63,63|96,100|102,106|110,111|114,114|116,117|123,123|135,142|145,151|156,159|161,163|165,172|177,179|183,184|191,193|196,196|200,201|204,211 ?EEEEEEBTT????HHHH-HHHHHHHH-T-T?---------EEE--E?-------?SSB---?H--------------------------------HHHHH-HHHHH-??SE--E-EE-----E??---------SGGGTHHH--HHHHHHH----HHTT?GGG?EEEEESTT--??HHH---HH------HHT-?S---EE?-SSHHHHHH 5REQ|A PF02311.14_AraC_binding_seed 58 179 !Q:13,13|15,16|19,19|23,24|36,36|40,40|47,51|55,55|58,58|63,63|66,67|73,73|75,83|86,86|97,99|106,109|118,131|133,135|150,155|161,162 Q:0,12|14,14|17,18|20,22|25,35|37,39|41,46|52,54|56,57|59,62|64,65|68,72|74,74|84,85|87,96|100,105|110,117|132,132|136,149|156,160|163,178 EEEEEEEETTSTT?S?-EE-ETT??SSEEEEEEEEE?EEE-EETTEE-----EEE?TT?EEEE?TT??EEEEE?T---------TS-SEEEEEEEEE???GGGGGG????EEETTEEE--------------E???TTTHHHHHHHHHHH------HHHHH??SSSHHHHHHHHHHHHH 1XJA|A PF02312.12_CBF_beta_seed 8 189 !Q:0,1|3,4|14,14|21,21|29,29|35,35|51,53|60,61|64,69|72,74|77,87|89,90|95,96|98,99|114,114|136,136|149,188 Q:2,2|5,13|15,20|22,28|30,34|36,50|54,59|62,63|70,71|75,76|88,88|91,94|97,97|100,113|115,135|137,148 ??S??SSHHHHHHH?HHHHHH?SSEEEEE?SGGGS?TTTHHHHHHHHHHHS???EEESSS??EE??????SS???SS??---------S??TTTS??S??SSEEEEEEEEESSS?EEEEEEEEETTTTEEEEEEEE?HHHHHHHHHHTT?--------------------------------------- 2JHB|A PF02313.12_Fumarate_red_D_seed 21 122 !Q:0,1|4,7|42,42|86,86|91,94|102,102|114,115|121,121 Q:2,3|8,41|43,85|87,90|95,101|103,113|116,120 ??SS????SHHHHHHHHHHHHHHHHHTHHHHHHHHHTTGGGT?SSTTTTSHHHHHHHHTSHHHHHHHHHHHHHHHHHHHHHHHHHH-HHTT???-TTHHHHH-HHHHHHHHHHH--HHHHS? 1KF6|D PF02315.11_MDH_seed 4 95 !Q:0,25|27,29|35,39|42,43|45,46|52,56|87,90|94,95 Q:26,26|30,34|40,41|44,44|47,51|57,86|91,93 ------------------------??S???SBTTB?????TT??S??TTSTT?????HHHHTHHHHHHHHHHHHHHHHHHHHHHHSS????GGG?- 2AD7|B PF02316.11_HTH_Tnp_Mu_1_seed 4 146 !Q:5,5|9,9|23,29|36,39|46,46|60,62|69,146 Q:0,4|6,8|10,22|30,35|40,45|47,59|63,68 HHHTT?SSS?SSHHHHHHHHHTT???????TTSSSS????EETTTS?HHHHHHHHHHTSS--?SSSSTT??---------------------------------------------------------------------------- 4FCY|A PF02317.12_Octopine_DH_seed 47 208 !Q:3,3|5,5|14,15|25,27|32,53|55,56|58,62|66,67|73,77|105,107|110,112|127,128|131,132|142,142|147,147|149,150|160,161|163,165|189,191|207,207 Q:0,2|4,4|6,13|16,24|28,31|54,54|57,57|63,65|68,72|78,104|108,109|113,126|129,130|133,141|143,146|148,148|151,159|162,162|166,188|192,206 EEE?S?HHHHHHTT-?TTHHHHHHH---HHHT----------------------T??S?---?BSS??BSGGG??---HHHHHHHHHHHHHHHHHHHHHHHHSTT???TT???HHHHHHHHSTTTBS??SS--HHHHHHTBG-GGTT?B??EEEETTEEE--E???SSTTTTTTTTTHHHHHHHHHHHT???HHHHHHHHHHHHHHT? 3C7A|A PF02318.11_FYVE_2_seed 21 130 !Q:3,3|56,56|60,61|66,66|69,72|75,75|79,80|83,83|86,86|90,99|105,105|117,117|122,122 Q:0,2|4,55|57,59|62,65|67,68|73,74|76,78|81,82|84,85|87,89|100,104|106,116|118,121|123,129 TTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSTTGGGTB?TTT??BGGG?SS??--EE?TTT??EE?GG-GEE?--------?SSSSS?EEHHHHHHHHH-HHHH?HHHHHHH 3BC1|B PF02319.15_E2F_TDP_seed 33 100 !Q:0,3|12,14|19,22|30,30|45,45|48,49|51,53|81,91|94,94|98,99 Q:4,11|15,18|23,29|31,44|46,47|50,50|54,80|92,93|95,97 ????HHHHHHHH---HHHH----HHHHSEE?HHHHHHHHHHHHHT?TT??G---GGSHHHHHHHHHHHHHHHHHHHHTTSB??--------?SS?EEB?? 1CF7|A PF02320.11_UCR_hinge_seed 24 74 !Q:0,1|33,33|36,47|65,65|72,73 Q:2,32|34,35|48,64|66,71 ??HHHHHHHHHTTSHHHHHHHHHHHHHHHHHTT?SS--------????SHHHHHHHHHHHHHHHH-HHHHHH?? 1SQB|H PF02321.13_OEP_seed 113 256 !Q:11,15|22,24|32,32|43,43|45,45|47,47|70,71|77,108|121,126|134,137|179,179|185,185|212,212|214,214|216,217|219,219|227,228 Q:0,10|16,21|25,31|33,42|44,44|46,46|48,69|72,76|109,120|127,133|138,178|180,184|186,211|213,213|215,215|218,218|220,226|229,255 HHHHHHHHTTT----?HHHHHH---HHHHHHH-HHHHHHHHGG-G-S?EEEEEEEEEEEEEEEESGGGSS??TTTSS?-------------------------------EEEEEEEEEEEE------EEEEEET----THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHH-HHHHHHHHHHHHHHHHHHHHHTTTSS?H-H--H-HHHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHT 1WP1|A PF02324.11_Glyco_hydro_70_seed 12 877 !Q:4,5|24,33|36,37|85,89|91,92|98,98|103,103|105,106|113,114|116,122|130,131|134,135|137,139|141,142|144,144|146,147|149,150|156,156|183,183|186,187|189,191|202,202|218,218|222,222|230,231|234,236|242,244|252,252|258,258|272,289|293,295|302,314|319,320|324,325|328,328|331,331|335,335|337,338|356,356|359,360|363,367|384,384|387,387|391,391|393,393|404,404|418,418|428,428|445,446|448,448|454,455|461,465|467,473|481,482|485,486|490,494|500,501|508,509|512,515|518,519|524,525|531,531|540,540|547,548|554,555|559,559|562,563|571,571|575,577|583,583|594,596|599,607|609,611|614,615|617,619|626,627|631,633|637,639|641,642|647,647|664,665|669,672|674,674|676,679|688,688|694,694|697,697|703,703|708,708|724,724|731,732|736,738|750,750|754,754|756,756|759,759|761,761|772,773|793,793|800,801|807,809|813,814|817,818|827,828|830,831|834,834|836,836|845,845|847,851|855,855|857,858|863,876 Q:0,3|6,23|34,35|38,84|90,90|93,97|99,102|104,104|107,112|115,115|123,129|132,133|136,136|140,140|143,143|145,145|148,148|151,155|157,182|184,185|188,188|192,201|203,217|219,221|223,229|232,233|237,241|245,251|253,257|259,271|290,292|296,301|315,318|321,323|326,327|329,330|332,334|336,336|339,355|357,358|361,362|368,383|385,386|388,390|392,392|394,403|405,417|419,427|429,444|447,447|449,453|456,460|466,466|474,480|483,484|487,489|495,499|502,507|510,511|516,517|520,523|526,530|532,539|541,546|549,553|556,558|560,561|564,570|572,574|578,582|584,593|597,598|608,608|612,613|616,616|620,625|628,630|634,636|640,640|643,646|648,663|666,668|673,673|675,675|680,687|689,693|695,696|698,702|704,707|709,723|725,730|733,735|739,749|751,753|755,755|757,758|760,760|762,771|774,792|794,799|802,806|810,812|815,816|819,826|829,829|832,833|835,835|837,844|846,846|852,854|856,856|859,862 GGGT??SSHHHHHHHHHHHHHHTT??--??--??TT??HHHHHHHHHHHHHHHHHHHHTTTSSHHHHHHHHHHHHHSGGGSGGGG?----S??SSTTS?EEEE?S??STTGGG??S???????TTTTTSS??TT??S---S-?S?S??S??SSEEE?TTSHHHHHHHHHHHHHHTTHHHHHHS?GG--G???EEEETTGGGS?THHHHHHHHHHHHHH?TTT?HHHHHTT??EE???STTHH---HHHHHTT?SSBEE?HHHHHHHHHHTTS-----------------?GGG???STHHHH-------------SSSS??SEE??SB?SS?EEE?S??SSTTTHHHHHHHHHHHT?TT??TT??--?HHHHHHHHHHHHHHHH?SS?SSS?S?HHHHHHHHHH?SSSEEEEEHHHHB?SSBSTTTSB?TTHHHHHHHHHHHHHH??S?EEEEE--EEETT-----E-------EEEEEEE??TT??STT??-??HHHHT??EEEEEE??TT????TT??EEEE??GGGTT?EEEEEEEE?SSSEEE??STGGG--GGG?EE??TTSEEEE?TTT???EESSS?EEEEEEEEES???TT?????????S???SS-?S???BHHHHT??EEE???TTB???S--SGGG?HHHHHHHTHHHHHHHT??EEE????S?B????SSHHHHTT?SSSBS?TT?SSSSS?BTTB?HHHHHHHHHHHHHTT?EEEEEE??SEE???SEEEEEEEEEE?TTS?B?TT?S?SSEEEEEEEE??SSSHHHHHTTTTHHHHHHH?HHHHHS??TTTSS???TTS??SS??GGGEEEEE??S??TT?B?EETTTTEE?B??---TTS?B??HHHH?----?-------- 2GJP|A PF02327.12_BChl_A_seed 2 357 !Q:0,0|11,12|15,17|27,27|29,30|32,32|48,48|54,54|116,117|124,124|127,131|144,145|163,163|192,194|203,208|223,224|235,235|239,239|242,242|252,252|255,255|279,282|297,298|308,309|312,312|320,321|347,351 Q:1,10|13,14|18,26|28,28|31,31|33,47|49,53|55,115|118,123|125,126|132,143|146,162|164,191|195,202|209,222|225,234|236,238|240,241|243,251|253,254|256,278|283,296|299,307|310,311|313,319|322,346|352,356 ?EEEEEEEEEE??TT???EEEEEEEEE?S??S?SSSSEEEEEEEEEEE?TTSTT?EEEEEEEEEEETTEEEEEEEEEEEEESSSSEEEEEEEEEEEETTEEEEEEEEEEEEEEESS??HHHHTT?SS?????EEEEEEEEEEEE??SHHHHHHHHHHHHHHHH?HHHHHHHHHHHHSTTTHHHHHHHTTEEE???EEEEEEEE??????EEEEEEEEEEEESS??HHHHTTTTTS?GGG?SS?EEEEEEEEE?SS?EEEEEEEEETTSEEEEETTEEEE????HHHHHHHHTTTTSS??EEEEEEEEE??TT?EEEEEES??SEEETTEEEEESHHHHHHHHHHHTT?????EEEEE 3BSD|A PF02329.11_HDC_seed 4 343 !Q:0,100|102,102|114,115|119,120|123,125|131,131|135,135|137,141|147,147|163,164|167,167|169,169|171,171|174,176|187,188|191,195|199,199|218,218|229,230|234,239|267,268|281,282|306,307|310,310|322,322|332,334|340,342 Q:101,101|103,113|116,118|121,122|126,130|132,134|136,136|142,146|148,162|165,166|168,168|170,170|172,173|177,186|189,190|196,198|200,217|219,228|231,233|240,266|269,280|283,305|308,309|311,321|323,331|335,339 ----------------------------------?-----------------------------------------------------------------?B?TTEEEBTTTBS??HHH--HH???SEEEE?TTS?E-----EEEEE?HHHHHHHHHHHEETT--EE?S?B?TT???EEEEEEEEEE??SS?????SSB?SEEEEEEEEEEESSTTTS?BEEEEEEEEE--SSS-----?HHHHHHHHHHHHHHHHHHHHHHHHHHT??EEEEEEEEEEEE??TTEEEEEEEEEEEEEEEGGGSTT??TT?HHHHHHHHHHS?HHHHHHHHT???SSTTT??? 1IBT|A PF02330.11_MAM33_seed 7 225 !Q:9,16|29,31|35,36|39,39|48,48|52,52|64,100|109,115|119,119|127,131|136,137|154,155|167,169|171,171|176,176|182,182|193,193 Q:0,8|17,28|32,34|37,38|40,47|49,51|53,63|101,108|116,118|120,126|132,135|138,153|156,166|170,170|172,175|177,181|183,192|194,224 HHHHHHHHH????????HHHHHHHHHHTT?--EEE??TT?SEEEEEEE?TTS?EEEEEEEHHHH?????????????-----???????????????????EEEEEEEE???????EEE-EEEEEET-----TTTE--EEEEEEEEESSHHHHH??SHHHHHHHHHS???S?GGGS?HHHHH-HHHHHHHHTT?SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 1YQF|A PF02331.10_P35_seed 7 359 !Q:0,5|10,12|20,21|37,40|43,44|47,47|57,57|64,64|66,66|79,84|91,101|104,111|115,115|118,118|124,124|134,135|139,140|156,156|159,164|166,167|169,178|180,182|185,186|192,192|199,199|201,202|209,210|218,224|227,230|237,239|247,248|251,251|260,260|262,265|267,267|270,270|278,279|291,291|294,295|300,302|305,306|332,335|337,352|357,358 Q:6,9|13,19|22,36|41,42|45,46|48,56|58,63|65,65|67,78|85,90|102,103|112,114|116,117|119,123|125,133|136,138|141,155|157,158|165,165|168,168|179,179|183,184|187,191|193,198|200,200|203,208|211,217|225,226|231,236|240,246|249,250|252,259|261,261|266,266|268,269|271,277|280,290|292,293|296,299|303,304|307,331|336,336|353,356 ??????SSTT???EEEEEEE--EETTEEEEEEEETGG----GS??SS?EEEEEEESS?EEEEEE-E?THHHHHHHHHHH------HHHHTT????-----??EE????????EEE?SS?EEEEE?THHHHHHTT??TTS??TTHHHHHHHHHHHTG-GG------T??S----------S???EE--EEEEE?TTTTSS-S??EEEEEE??STTEEEE???????SS?--?EEEEEE---EEEESEE??HH-HHHHHHHT?B????S?TT?EEEEEEE??SSEEEEEEEEE?EE??SSSS???EE??EEEEEEEEETTTTEEEEEEEEEEES????E----------------EEEE?? 1I4E|A PF02332.13_Phenol_Hydrox_seed 23 251 !Q:0,4|7,7|13,13|18,19|22,23|30,32|35,37|55,55|64,64|70,71|76,76|84,84|102,102|106,108|110,110|120,120|127,129|146,146|154,156|162,163|179,179|182,182|207,207|216,216|249,249 Q:5,6|8,12|14,17|20,21|24,29|33,34|38,54|56,63|65,69|72,75|77,83|85,101|103,105|109,109|111,119|121,126|130,145|147,153|157,161|164,178|180,181|183,206|208,215|217,248|250,250 ?????SS?HHHHS?HHHH??TT??HHHHTT???SS???HHHHHHHHHHHHHHHHH-HHHHHGGG?GGGGS-?HHHH-HHHHHHH-HHHHHHHHHHHHHHHHH-HHH?--S?HHHHHHHHH-HHHHHH---HHHHHHHHTGGGGGGG?GGGGHHH---HGGGS??HHHHHHHHHHHHHTT-SS?HHHHHHHHHIIIIITTHHHHHHHH-HHHHHHTT?HHHHHHHHHHHHTHHHHHTTHHHHHHHHHHTT?H 3N20|A PF02333.10_Phytase_seed 2 381 !Q:0,30|33,33|38,39|43,46|49,49|52,52|60,61|64,64|68,68|78,79|83,83|87,87|92,93|96,96|121,121|125,126|143,143|145,145|149,150|152,152|165,165|169,170|190,190|205,205|208,208|240,240|242,243|249,249|254,255|257,257|266,266|270,270|292,293|301,303|307,310|312,314|319,319|321,322|326,326|329,329|346,347|363,366|370,372|376,380 Q:31,32|34,37|40,42|47,48|50,51|53,59|62,63|65,67|69,77|80,82|84,86|88,91|94,95|97,120|122,124|127,142|144,144|146,148|151,151|153,164|166,168|171,189|191,204|206,207|209,239|241,241|244,248|250,253|256,256|258,265|267,269|271,291|294,300|304,306|311,311|315,318|320,320|323,325|327,328|330,345|348,362|367,369|373,375 ----------------------------???SS?EEEE??SEE????SS?SS?EEEEEEE??SS?GGG?EEEEEESSS??EEE?TTS?EEEE??SS?EEEEEEEEEEEETTEEEEEEEEEE?GGG??EEEEEEEETTTTEEEE?B?SSS??B?SSSSEEEEEEEE?TTT??EEEEEEETTSEEEEEEEEE?TTSSEEEEEEEEEE?SS?EEEEEEETTTTEEEEEETTTEEEEEESSGGG?S??EEEEE?SSSS??S?EEEEEEEE?GGG?EEEEEEEGGGTEEEEEESSTT??EEEEEEE???SSS????S???EEEE?S??SSS?TT?EEEEEESSEEETTEEE??EEEEEEHHHHHGGGT????TTS???TTS????? 3AMR|A PF02334.11_RTP_seed 3 122 !Q:0,3|5,8|12,13|30,31|49,52|76,76|82,82|91,91|121,121 Q:4,4|9,11|14,29|32,48|53,75|77,81|83,90|92,120 ????S????SSS??HHHHHHHHHHHHHHTT??BSTTHHHHHHHHHTTTT????HHHHHHHHHHHHHTTSEEEEEEE?TTSTT?EEEEEEES?HHHHHHHHHHHHHHHHHHHHHHHHHHHHH? 2DPD|A PF02335.10_Cytochrom_C552_seed 38 652 !Q:1,1|6,13|29,60|66,66|81,82|84,87|98,98|102,104|109,109|111,115|126,126|139,145|160,168|170,183|185,185|191,191|194,194|198,204|206,209|211,211|222,247|250,251|254,254|269,270|273,317|321,323|326,328|331,331|333,338|352,363|367,367|371,372|375,380|387,387|396,397|404,404|408,408|411,412|416,420|422,423|426,426|431,433|440,442|444,444|478,493|498,498|502,503|509,513|539,539|570,571|573,584|595,596|605,606|614,614|618,618|627,651 Q:0,0|2,5|14,28|61,65|67,80|83,83|88,97|99,101|105,108|110,110|116,125|127,138|146,159|169,169|184,184|186,190|192,193|195,197|205,205|210,210|212,221|248,249|252,253|255,268|271,272|318,320|324,325|329,330|332,332|339,351|364,366|368,370|373,374|381,386|388,395|398,403|405,407|409,410|413,415|421,421|424,425|427,430|434,439|443,443|445,477|494,497|499,501|504,508|514,538|540,569|572,572|585,594|597,604|607,613|615,617|619,626 S-STTT--------TTSHHHHHHHHTTTT--??---------?----------------??BHHHH?THHHHHTTTSGGGT??B????GGGHHHHHHH?STT???SSTT?S-----SSBGGGGTTT?THHHHHHHHHHH-------HHHSSSBTGGGTTT??-------S?-------------S?HHHHB?SS-SSS-------B????H-HHHHHHHHTT?-----------------------?-ST--TS?HHHHHHHTTTTTSS??EE???------------------------------------------SSS???EE???SS?S------STTHHHHHHHHTT----------??SEE?TTT??EE??????HHHHHT-TSHHHHTT??HHHHHS?EEE?TT??EEE???-?S-?GG-GGTT---TTGGGT??-S?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH----------------HHHH-HTT??HHHHH-----HHHHHHHHHHHHHHHHHHSTTHHHH?HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??S----????????SHHHHHHHHT??SHHHHHHH--HHHHHHT-HHH-HHHHHHHH??---------------------?? 3LG1|A PF02336.10_Denso_VP4_seed 3 442 !Q:0,38|41,42|53,55|57,59|62,62|68,68|80,81|89,90|97,98|101,101|103,105|118,121|123,123|127,130|132,135|149,149|151,158|162,163|165,172|177,177|181,181|184,184|191,193|196,196|206,207|212,213|217,219|224,225|231,236|244,245|254,257|260,261|264,264|266,266|268,271|273,277|286,292|294,295|297,297|300,304|306,306|310,310|312,316|319,327|330,330|337,338|342,344|347,356|362,363|365,368|371,372|374,376|378,379|391,392|395,399|403,404|406,407|409,409|413,419|422,422|425,425|429,430|434,435|438,441 Q:39,40|43,52|56,56|60,61|63,67|69,79|82,88|91,96|99,100|102,102|106,117|122,122|124,126|131,131|136,148|150,150|159,161|164,164|173,176|178,180|182,183|185,190|194,195|197,205|208,211|214,216|220,223|226,230|237,243|246,253|258,259|262,263|265,265|267,267|272,272|278,285|293,293|296,296|298,299|305,305|307,309|311,311|317,318|328,329|331,336|339,341|345,346|357,361|364,364|369,370|373,373|377,377|380,390|393,394|400,402|405,405|408,408|410,412|420,421|423,424|426,428|431,433|436,437 -----??????????????????????????????????EE??EEEEEEEEEE???S???EE?SSTTT?SBEEEEEEEEE??TTBGGGT??HHHHHT??TT?B???EEEEEEEEEEEE????S?TTS????S????EEEEESTHHHHTT?B????????SSS??S????????SSEE?SSS?EE?HHHHHH???SS?TTSSSSSSS??GGGG??EEE???EEEE??BSSSS??????GGGGSEE??TTTTTTSB????EE??SS?B?S????B?????TTBTTBBS???????S??S?EE?????B?SSS?B?????EE?????????SS?TTSSBS??TTT???TT??????????EEEEE??B????SS??S???B??EEEEEEEEEEE??EE?????STT??S??B?TTT???????SS?SS?SSS??SSS??SS???? 1DNV|A PF02337.12_Gag_p10_seed 5 91 !Q:0,2|5,5|23,26|41,47|50,50|71,72|75,75 Q:3,4|6,22|27,40|48,49|51,70|73,74|76,90 ???SS?HHHHHHHHHHHHHHTTT????HHHHHHHHHHHHHH???????SS?HHHHHHHHHHHHHHHHHHHS??SS?THHHHHHHHHHHHHH 2F76|X PF02338.14_OTU_seed 51 237 !Q:0,1|4,5|19,20|23,23|32,34|40,46|56,67|73,116|132,152|155,158|163,163|171,172|175,175|180,209|213,214|218,218|223,224|226,226 Q:2,3|6,18|21,22|24,31|35,39|47,55|68,72|117,131|153,154|159,162|164,170|173,174|176,179|210,212|215,217|219,222|225,225|227,236 ??SS?-HHHHHHHHHHHSS??TT?HHHHHHHH---HHHSS?-----?HHHHHHHHH------------HHHHT?????????????------------------------------?HHHHHHHHHHHTSSS?-------------???????SS????HHHH-HHHHHHH--TS?EEEE?-------????????????---???????EEE??TTS?GGGS??S?EEEEEETTEE 3TMP|A PF02341.10_RcbX_seed 16 111 !Q:0,1|33,33|46,46|48,48|51,51|63,63 Q:2,32|34,45|47,47|49,50|52,62|64,110 ??HHHHHHHHHHHHHHHHHHHHHHHHHHHTTTT?HHHHHHHHHHST-T?TT?HHHHHHHHHTT?HHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHH 4GR2|A PF02342.13_TerD_seed 187 442 !Q:0,28|36,41|45,72|74,76|80,80|85,85|88,100|115,115|117,117|125,151|154,156|160,252|264,267|270,271|287,299|306,306|309,309|316,332|340,345|350,352|358,358|370,398|404,410|418,424|431,432|439,441 Q:29,35|42,44|73,73|77,79|81,84|86,87|101,114|116,116|118,124|152,153|157,159|253,263|268,269|272,286|300,305|307,308|310,315|333,339|346,349|353,357|359,369|399,403|411,417|425,430|433,438 ?????????---??????????-----??EEEEEEE-?????SSS----------------------------S???EEE?EEEE?TT-------------SSBSSGGGEEBTTB?B?TTSSEEE-----------------------????SS??-SSS?--------------------------------------------------------------------------------------------SEEEEEEGGGS?---TT??EEEEEEEETTHHHHT-----------??GGGSSS?EE-EEEETT-----------------TTEEEEE------EEHH---HHSTT?SEEEEEEEEEE-----------------------------TTEEE-------EEEEEEE?------TTHHHH--HHHHTT??? 2KXV|A PF02344.10_Myc-LZ_seed 2 32 !Q:27,31 Q:0,26 HHHHHHHHHHHHHHHHHHHHHHHHHHH???-- 1A93|A PF02346.11_Vac_Fusion_seed 11 57 !Q:35,56 Q:0,34 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?--------------------- 3VOP|A PF02347.11_GDC-P_seed 13 468 !Q:3,3|6,6|19,19|31,31|35,37|39,59|73,74|77,80|83,85|88,94|104,104|110,113|119,119|139,139|143,143|145,145|148,148|164,165|168,170|179,179|195,195|201,201|205,219|221,221|231,231|236,242|254,254|261,261|269,270|276,276|283,283|288,290|294,297|303,303|306,310|315,316|318,318|329,329|336,342|349,356|397,398|400,400|403,404|415,416|418,418|424,424|434,435|438,438|441,441|445,445|451,452|455,456 Q:0,2|4,5|7,18|20,30|32,34|38,38|60,72|75,76|81,82|86,87|95,103|105,109|114,118|120,138|140,142|144,144|146,147|149,163|166,167|171,178|180,194|196,200|202,204|220,220|222,230|232,235|243,253|255,260|262,268|271,275|277,282|284,287|291,293|298,302|304,305|311,314|317,317|319,328|330,335|343,348|357,396|399,399|401,402|405,414|417,417|419,423|425,433|436,437|439,440|442,444|446,450|453,454|457,467 HHH?SS?HHHHHHHHHHHT?SSHHHHHHHHS?TTT???S???????------------??HHHHHHHHHHHHT--TB??-?EE???TT???????HHHHHHTTT?HHHHS????SSGGG?HHHHHHHHHHHHHHHHHHT?SEE?S?BS?HHHHHHHHHHHHHHH??SS-??EEEEETTS?HHHHHHHHHHHGGGT?EEEEE?TTT????-----------S?EEEEEEEES?TTSB???---?HHHHHHHHHTT?EEEEEE?TTGGGTB??HHHHT?SEEEEE?TTTT???GGG????EEEEE?GG-----GGGG??S?EEEEEEBTTS?EEEEEE???????TTHHHH????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT--T?EE??SSBSSEEEEE??T-TTHHH-HHHHHHHTT--EE?EE?STT-EEEEE??TT??HHHHHHHHHHH 1PFF|A PF02348.14_CTP_transf_3_seed 20 307 !Q:5,9|18,18|38,39|42,45|52,52|64,66|71,73|76,77|91,93|96,100|105,106|109,109|112,113|115,115|130,147|156,158|164,164|168,168|173,173|176,181|191,191|194,195|202,203|205,205|209,215|218,218|231,234|243,245|247,257|264,273|278,282|288,305 Q:0,4|10,17|19,37|40,41|46,51|53,63|67,70|74,75|78,90|94,95|101,104|107,108|110,111|114,114|116,129|148,155|159,163|165,167|169,172|174,175|182,190|192,193|196,201|204,204|206,208|216,217|219,230|235,242|246,246|258,263|274,277|283,287|306,306 EEEEE?????SSSTTGGG?EETTEEHHHHHHHHHHHTT?-SE----EEEEES?HHHHHHHHHTT--?EEEE???SS??HHHHHHHHHHHTT??-TT?----EEEE??TT?TT??H-HHHHHHHHHHHHHT?-----------------SEEEEEEE???HHHHT?TTS?EEEE?TT------SBEEEEESS?SS??HHHHTT-?S?GGG---????TT?EEEEEEEEEEHH----HHHHHHHS???H-----------HHHHHT?---------TTHH-----HHHTT----------------??E 4FCU|A PF02350.14_Epimerase_2_seed 187 510 !Q:5,5|7,7|9,14|21,22|25,26|36,47|51,55|59,66|70,70|72,72|92,96|101,103|108,108|123,125|131,135|137,161|166,166|180,180|199,214|217,221|226,228|232,234|238,243|253,253|256,258|267,267|269,276|278,279|288,291|295,296|299,300|313,315|318,318|322,322|328,329|331,331|339,350|357,358|360,366|372,375|386,386|390,401|407,407|416,417|420,426|430,432|435,436|438,438|447,449|453,457|460,460|474,478|488,488|490,491|494,496|498,498|500,500 Q:0,4|6,6|8,8|15,20|23,24|27,35|48,50|56,58|67,69|71,71|73,91|97,100|104,107|109,122|126,130|136,136|162,165|167,179|181,198|215,216|222,225|229,231|235,237|244,252|254,255|259,266|268,268|277,277|280,287|292,294|297,298|301,312|316,317|319,321|323,327|330,330|332,338|351,356|359,359|367,371|376,385|387,389|402,406|408,415|418,419|427,429|433,434|437,437|439,446|450,452|458,459|461,473|479,487|489,489|492,493|497,497|499,499|501,509 HHHHH?T-T-----?EEEEEE??TT--GGGGHHHHH------------HTT?--??SEE----????SSS-S?HHHHHHHHHHHHHHHHHHH--??-SEEE---EETT?HHHHHHHHHHHTTT??-EEEES?????S------------------------?TTSS-TTHHHHHHHHHHT?SEEEESSHHHHHHHHHTT----?----------?GG-----GEEE???HHH---HHH------HHHHHHTTT?HH---HHHHHHTT?T--------T??TTSEEEEE????BSS??HH--HHHHHHHHHHHH---HH?TTE-EEEEE??B?HHHHHHH------------HHHHTT?-T-------TEEEE????HHHHHHHHHH?SEE------------EESSS-GGGGTGGG--GT-----??EEE?--SS??S?HHHHHHTS---EEE-?-?-SS-HHHHHHHHHHHHH?----HHHHHHHHH-S??TT?-?S?H-HHHHHHHHH 1F6D|A PF02351.11_GDNF_seed 64 145 !Q:5,5|21,26|32,56|61,62|64,65|68,82|95,95|101,116|118,118|120,120|123,123|128,128|140,140|142,142|145,145 Q:0,4|6,20|27,31|57,60|63,63|66,67|83,94|96,100|117,117|119,119|121,122|124,127|129,139|141,141|143,144 HHHHH-HHHHTSHHHHHHHHH------HHHHT??-----------------------SSSS??S??GG---------------GHHHHHHHHHTT-TTSTT???????????--???S?B?TT?GGGH-HHHHHHHHHHH-S?HH- 2GH0|A PF02352.10_Decorin_bind_seed 12 148 !Q:25,31|34,36|43,43|45,45|76,76|78,78|82,87|106,108|122,124 Q:0,24|32,33|37,42|44,44|46,75|77,77|79,81|88,105|109,121|125,147 HHHHHHHHHHHHHHHHHHHHHHHHS???????SS???STTSSS?H-HHHHHHHHHHHHHHHHHHHHHHHHHHHTTT?H-HHH------HHHHHHHHHHHHHHHHHH???SHHHHHHHHHHHS???SHHHHHHHHHHHHHHHHHHHHHH 2LQU|A PF02353.15_CMAS_seed 12 300 !Q:0,1|3,5|16,16|25,25|28,30|32,35|38,44|47,48|66,67|70,70|77,77|91,92|100,100|114,117|119,119|126,126|130,137|145,145|150,157|173,173|176,176|186,187|196,196|198,198|217,221|228,228|235,235|243,243|269,269|271,271 Q:2,2|6,15|17,24|26,27|31,31|36,37|45,46|49,65|68,69|71,76|78,90|93,99|101,113|118,118|120,125|127,129|138,144|146,149|158,172|174,175|177,185|188,195|197,197|199,216|222,227|229,234|236,242|244,268|270,270|272,299 ??S???HHHHHHHHTS?HHHHTTTS?TT???S????SS-------TT??HHHHHHHHHHHHHTTTT??TT?EEEEET?TTSHHHHHHHHHH??EEEEEES?HHHHHHHHHHHHT????S?EEEEES?GGG???---??SEEEEES?GGGT-------?TTTHHHHHHHHHHHS?TT?EEEEEEEEE??HHHHTTTT?S?HHHHHHHHHHHHHHTSTT?????HHHHHH-HHHTTT?EEEEEEE?HHHHHHHHHHHHHHHHHTHHHHHHH-S?HHHHHHHHHHHHHHHHHHHTTSEEEEEE 3BKX|A PF02355.11_SecD_SecF_seed 19 209 !Q:11,12|14,16|22,22|53,53|64,64|81,89|121,121|124,126|128,128|151,155|167,173|208,208 Q:0,10|13,13|17,21|23,52|54,63|65,80|90,120|122,123|127,127|129,150|156,166|174,207 HHHHHHHHHSS--S???EEEEE?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHS?HHHHHHHHHH-HHHHHHHHHHHHHHHT-----????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?SS---S?HHHHHHHHHHHHHHHHHHHHHH-----HHHHHHHHHHH??-----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH? 3AQP|A PF02357.14_NusG_seed 170 190 !Q:0,0|8,8|14,16|18,19|23,25|28,28|30,33|35,36|38,39|45,45|48,55|57,59|61,62|65,65|68,72|74,78|80,86|91,97|106,112|114,119|121,125|127,128|132,138|143,143|149,151|154,160|162,165|171,185|187,187 Q:1,7|9,13|17,17|20,22|26,27|29,29|34,34|37,37|40,44|46,47|56,56|60,60|63,64|66,67|73,73|79,79|87,90|98,105|113,113|120,120|126,126|129,131|139,142|144,148|152,153|161,161|166,170|186,186|188,189 ?EEEEEEE?TTSHH---H--HHH---HH-H----H--H--HHHHT?TT--------T???B??SS?SS---??S?--??S-------STTS--?????TTEEEEEE???----H------H-----H--HHH-------HHHS-SSEEE---EE-------S----SSSSS-----???-------B?HH 1NPP|A PF02358.11_Trehalose_PPase_seed 24 278 !Q:3,3|9,11|13,14|18,21|37,38|43,43|46,46|50,52|58,58|61,61|77,77|81,99|126,126|139,139|143,143|146,149|166,166|168,168|173,173|181,181|184,186|199,221|231,231|243,251|260,269 Q:0,2|4,8|12,12|15,17|22,36|39,42|44,45|47,49|53,57|59,60|62,76|78,80|100,125|127,138|140,142|144,145|150,165|167,167|169,172|174,180|182,183|187,198|222,230|232,242|252,259|270,277 EEE?BTTTB???S?-GGG????HHHHHHHHHHHHHSE--EEEE?SS?HHH---HHHHS?SS?EEEEGGGTEEEETTE-EEE?------------------TTGGGGHHHHHHHHHHHTTHHHHSTT?EEEEETTEEEEE?TTS?ST----THHHHHHHHHHHHHHH-T?EEEE?SSEEEEE?TT??-HHHHHHHHHTTS?----------------------EEEEESSHH-HHHHHHTTTTS---------EEEEESSS?------???SEEESSHH 1U02|A PF02359.13_CDC48_N_seed 120 101 !Q:6,6|8,8|10,17|24,24|33,34|37,37|43,43|47,47|51,51|57,57|61,70|77,77|86,87|90,90|97,97|100,100 Q:0,5|7,7|9,9|18,23|25,32|35,36|38,42|44,46|48,50|52,56|58,60|71,76|78,85|88,89|91,96|98,99 EEEEEE?S-S?------?TTEEEE?HHHHHHTT??TT?EEEEE?STT?EEE-EEEEE?SSS-----?----TTEEEE?HHHHHHTT??TT?EEEEEE?TT? 3HU2|A PF02361.11_CbiQ_seed 21 355 !Q:0,8|26,27|33,35|50,58|64,64|79,105|115,115|119,120|122,182|186,215|236,239|245,245|265,266|300,304|306,306|308,308|327,327|345,345|347,349|352,354 Q:9,25|28,32|36,49|59,63|65,78|106,114|116,118|121,121|183,185|216,235|240,244|246,264|267,299|305,305|307,307|309,326|328,344|346,346|350,351 ?????????SHHHHHHHHHHHHHHHS??SSSHH---HHHHHHHHHHHHHS------???THHHH-HHHSTTHHHHHHHH---------------------------HHHHHTSSS?TTS??S??------------------------------------------------------?????HHH------------------------------HHHHHHHHHHHHHHHHHHHH----HHHHS?SSTHHHHHHHHTHHHHTTT??SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT???--S?S?SHHHHGGGHHHHHHHHHH-HHHHHHHHHHHHHHSSS?S-??SS??? 4HZU|T PF02362.16_B3_seed 114 168 !Q:4,10|18,24|26,28|31,31|35,36|41,42|44,46|49,50|53,63|71,71|75,86|94,95|98,102|109,113|118,124|136,138|141,141|148,153|157,158|165,167 Q:0,3|11,17|25,25|29,30|32,34|37,40|43,43|47,48|51,52|64,70|72,74|87,93|96,97|103,108|114,117|125,135|139,140|142,147|154,156|159,164 EEEE?-----?TTTTSSS-----??E---EE?HHH--HTTT--S???SS??SS---------??EEEEEEE-TTT------------EEEEEEE--EE-----ETTTTE-----EEEE-------SSHHHHHHHTT??-TT?EEEEEE----??SSS??EEEEEE??? 4I1K|A PF02365.10_NAM_seed 133 300 !Q:0,1|4,9|22,22|26,39|42,43|45,63|66,72|77,78|80,80|84,85|87,87|89,89|91,115|118,127|130,131|134,135|137,140|145,168|170,170|172,172|174,195|198,202|206,207|210,210|212,212|214,217|221,235|239,252|262,265|267,273|275,275|280,280|282,285|294,294|298,299 Q:2,3|10,21|23,25|40,41|44,44|64,65|73,76|79,79|81,83|86,86|88,88|90,90|116,117|128,129|132,133|136,136|141,144|169,169|171,171|173,173|196,197|203,205|208,209|211,211|213,213|218,220|236,238|253,261|266,266|274,274|276,279|281,281|286,293|295,297 ??TT??????HHHHHHHTHHHH-HHT??-----------?SS--S----------------?-?EE?-?----GGGS-?G-GGS--G-G-G------------------------?SS---------?SS--EE--E----EEEE??????----?-??---------?S?E-E----------------------ET-----TEE--EE-E?S?--?EEE??-------------SSS?------------?EEEEEEEEE----E-------S-STTS?E----EEEEEEEE-EEE-? 3ULX|A PF02367.12_UPF0079_seed 14 143 !Q:15,16|19,21|44,44|46,47|49,54|65,68|71,71|78,78|81,83|91,95|100,100|104,104|112,112|119,119|122,124|127,128|138,138 Q:0,14|17,18|22,43|45,45|48,48|55,64|69,70|72,77|79,80|84,90|96,99|101,103|105,111|113,118|120,121|125,126|129,137|139,142 HHHHHHHHHHHHHHS??SS???EEEEESTTSSHHHHHHHHHHTT-T??S--????SSSSSEEEEE?---SS?EEEEEE?SS???GGGHHHH-----GGGT?SSS-SEEEEEE?TTSTTS-SS???SE--EEEEEESSS?EEEE 1FL9|A PF02368.13_Big_2_seed 46 108 !Q:10,16|20,21|28,28|39,44|46,46|52,52|54,54|61,70|74,74|77,79|82,82|84,85|88,88|98,99|101,101 Q:0,9|17,19|22,27|29,38|45,45|47,51|53,53|55,60|71,73|75,76|80,81|83,83|86,87|89,97|100,100|102,107 EEEEEEETTT-----??EES??SEEETT?EEEEEEESTT------S?EEEEE-S?TTTEEE?---------TTT?EE---EE?S--SS?EEEEEEETT--S?EEEEEE 4AQ1|A PF02369.11_Big_1_seed 20 116 !Q:0,9|17,17|25,27|37,37|42,43|45,45|50,54|56,56|63,63|65,65|67,69|72,73|84,84|86,91|93,93|97,98|104,104|106,106|108,109|112,114 Q:10,16|18,24|28,36|38,41|44,44|46,49|55,55|57,62|64,64|66,66|70,71|74,83|85,85|92,92|94,96|99,103|105,105|107,107|110,111|115,115 --------??EEEEEES?SEEESSS???EEEEEEEEE-TTEE??S?EEEE-----E?SSSEES?S-E---EE??TTSEEEEEEE?S------S?EEE??EEEET-T?S??EE???E 1F02|I PF02370.11_M_seed 59 21 !Q: Q:0,20 HHHHHHHHHHHHHHHHHHHHH 2KK9|A PF02372.10_IL15_seed 14 144 !Q:0,15|17,19|22,29|46,50|54,55|58,59|82,83|85,85|103,114|116,118|126,126 Q:16,16|20,21|30,45|51,53|56,57|60,81|84,84|86,102|115,115|119,125|127,143 ????------------H---HH--------HHHHHHHHHHHHHTTS?????EEE-?SS??GGGHHHHHHHHHHHHHHHHHHH--T?HHHHHHHHHHHHHHHTT???--???????S???GGGSEEE?HHHHHHHHHHHHHHHSS 2PSM|A PF02373.17_JmjC_seed 32 129 !Q:5,5|8,8|14,15|19,19|22,24|33,33|40,40|49,51|58,61|68,68|72,72|77,81|85,86|92,94|100,100|103,103|108,108|111,111 Q:0,4|6,7|9,13|16,18|20,21|25,32|34,39|41,48|52,57|62,67|69,71|73,76|82,84|87,91|95,99|101,102|104,107|109,110|112,128 EEEEE?TT?EEEEE??GGG?EE---EEEEEEES?EEEEEE?GGGHHHHH---HHHHHH?---HHHHHH?TTH-HHHS?????HHH--HHHTT???EEEEE?TT?EEEE?TT?EEEEEESSSEEEEEEEE 3N9O|A PF02374.10_ArsA_ATPase_seed 11 344 !Q:0,0|24,25|31,32|38,39|42,42|51,58|62,62|65,65|68,68|76,77|80,85|102,102|106,108|110,110|124,124|142,149|151,151|157,157|159,161|187,190|204,213|237,237|248,248|269,270|279,279|281,282|284,291|323,324|327,327|329,329|342,343 Q:1,23|26,30|33,37|40,41|43,50|59,61|63,64|66,67|69,75|78,79|86,101|103,105|109,109|111,123|125,141|150,150|152,156|158,158|162,186|191,203|214,236|238,247|249,268|271,278|280,280|283,283|292,322|325,326|328,328|330,341 ?EEEEEEESTTSSHHHHHHHHHHH--HHHSS??EEEEE??SS?HHHHHHTS------??BSS?EE?TT?SSEEEEE??HH------HHHHHHHHHHHHHGGG?HHH---H-HHHHHHHHHHHHS-HHHHHHHHHHHHHHHHS------??S?SEEEE?S???TTTTGGGGHHHHHHHHHHHHHHHHH----HHHHHHHHHHHHS??????????HHHHHHHHHHHHHHHHHHHHHHH?TTTEEEEEEE?SSHHHHHHHHHHHHHHHHHT??EEEEEEEE-E??S???-----SHHHHHHHHHHHHHHHHHHHHSTTSEEEEEE??SS?S?SHHHHHHHHHHH?? 3B2E|A PF02375.12_JmjN_seed 65 42 !Q:0,0|3,5|11,11|19,20|24,27|31,32|40,41 Q:1,2|6,10|12,18|21,23|28,30|33,39 ?EE???HHHHT?HHHHHHH--HHH----HHG--GGSEEEE?? 2OT7|A PF02376.10_CUT_seed 26 135 !Q:5,9|23,41|45,46|56,61|68,69|73,84|86,95|100,100|116,116|118,119|129,131|133,133 Q:0,4|10,22|42,44|47,55|62,67|70,72|85,85|96,99|101,115|117,117|120,128|132,132|134,134 HHHHH?????HHHHHHHHHHHHH-------------------HTT??HHHHHHHTT?---??HHHHHH--HHH------------S?-------??TTTS?HHHHHHHHHHHHHHH?T--THHHHHHHH---H?S 1X2L|A PF02378.13_PTS_EIIC_seed 55 469 !Q:22,37|47,54|57,57|59,60|92,97|100,100|104,105|119,119|121,121|132,162|167,167|200,200|203,203|205,208|212,212|216,220|238,238|251,251|264,266|294,294|307,317|331,339|342,362|364,365|372,379|400,401|415,437|443,444|456,456|459,459 Q:0,21|38,46|55,56|58,58|61,91|98,99|101,103|106,118|120,120|122,131|163,166|168,199|201,202|204,204|209,211|213,215|221,237|239,250|252,263|267,293|295,306|318,330|340,341|363,363|366,371|380,399|402,414|438,442|445,455|457,458|460,468 HHHHTTTHHHHHHHHHHHTTTT-------------???TTTHHHHHH--------HT?S??TTGGGHHHHHHGGGHHHHHHHHHHHHHHHHH------TS?HHH--HHHHHHHHHHHHS?S?EEEEETTTTE-------------------------------EEEE?SEEETTTSSTTTHHHHHHHHHHHHHHHHHHHH-TT?S????TTS?HHH-----HHHHHHHHHHHHHHHHH-HHHHHHHTTSSS?SHHHHHHHHTTT---HHHHHHTSTGGGTHHHHHHHHHHTTTS?HHHHHHHHHHHH-----------HHHHTHHHHHHHT---------TT?----------------????S??HHHHHH--------HTSSSSSSSHHHHHHHHHHS??SHHHHHHHHTTHH-----------------------HHHTT??HHHHTTTTTTT?SS-THHHHHHHH 3QNQ|A PF02380.10_Papo_T_antigen_seed 10 95 !Q:0,3|6,8|11,12|14,14|24,27|30,32|45,45|49,50|52,54|59,59|70,71|88,95 Q:4,5|9,10|13,13|15,23|28,29|33,44|46,48|51,51|55,58|60,69|72,87 ????SS???TT??S?SSHHHHHSS??-?SB?-?HHHHHHHHHHHH-TTT??S???BTTB?SHHHHHHHTT??SSHHHHHHHHHHHTTS???????- 2PF4|E PF02381.13_MraZ_seed 23 77 !Q:2,2|8,10|17,18|26,26|29,33|36,39|43,44|48,48|60,60|64,64 Q:0,1|3,7|11,16|19,25|27,28|34,35|40,42|45,47|49,59|61,63|65,76 SB?SEEEE???TTSEEE??SHHHHHS?SE-----EB????TTS??EEB?HHHHHHHHHHH-HHS?SSSHHHHHHHHH 1N0G|A PF02383.13_Syja_N_seed 158 1005 !Q:10,11|14,21|32,32|40,50|53,61|64,65|67,67|77,78|80,80|83,266|279,289|292,295|298,303|306,307|309,310|312,324|326,326|329,341|343,343|345,349|351,355|361,361|363,418|423,424|428,428|438,438|444,480|482,482|489,492|496,524|535,607|620,624|628,629|632,632|635,635|638,639|641,642|644,644|654,687|689,752|754,784|788,789|801,803|807,819|822,829|831,840|845,846|857,857|862,881|890,903|906,910|924,959|962,972|975,976|981,983|986,991|993,995|998,999 Q:0,9|12,13|22,31|33,39|51,52|62,63|66,66|68,76|79,79|81,82|267,278|290,291|296,297|304,305|308,308|311,311|325,325|327,328|342,342|344,344|350,350|356,360|362,362|419,422|425,427|429,437|439,443|481,481|483,488|493,495|525,534|608,619|625,627|630,631|633,634|636,637|640,640|643,643|645,653|688,688|753,753|785,787|790,800|804,806|820,821|830,830|841,844|847,856|858,861|882,889|904,905|911,923|960,961|973,974|977,980|984,985|992,992|996,997|1000,1004 ESEEEEEEEE--TT--------EEEEEEEEEE-EEEEEET-----------TE---------EE--E-EEEEEEEEE--S?TT?------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------???HHHHHHHHHHHH-----------HH----HH---???EE?-S--S-------------S?TT-------------S?H-----H-----HHHHH?S?-----------------------------------------------------??GGGS?-TTT?TTTGGGHHH-HHHHT-------------------------------------T?GGGGGG????BSS-----------------------------EEEEEEEEET-------------------------------------------------------------------------TEEEEEEEEEEE?????SSS??SS-SB?TT--S??S?EEEEEEEEE----------------------------------E----------------------------------------------------------------E------------------------------?TTT??EEEEEEEEEEE???SBS??-??-----?--SS--------S???????---HHHH--HHHHHHHHHH-HHHH--------------------SEEEEEEE?-----------??SS??--?HHHHHHHHHHHHH--------------------------------?--?TT-----------EE--EEEE???SS------T---TT--HHHHH 3LWT|X PF02384.11_N6_Mtase_seed 15 391 !Q:0,3|22,23|28,30|42,48|52,52|58,58|61,61|79,79|81,81|92,95|97,100|116,118|120,125|129,130|135,135|137,137|139,146|148,149|156,158|161,162|164,174|180,180|182,183|188,196|199,199|204,205|231,232|248,248|255,256|260,261|263,264|267,267|276,279|286,288|297,297|300,300|306,307|310,310|313,314|331,347|351,351|354,358|375,377|382,390 Q:4,21|24,27|31,41|49,51|53,57|59,60|62,78|80,80|82,91|96,96|101,115|119,119|126,128|131,134|136,136|138,138|147,147|150,155|159,160|163,163|175,179|181,181|184,187|197,198|200,203|206,230|233,247|249,254|257,259|262,262|265,266|268,275|280,285|289,296|298,299|301,305|308,309|311,312|315,330|348,350|352,353|359,374|378,381 ????SHHHHHHHHHHHHHHTTT??STTT???HHHHHHHHHHH----???SEE-EEESS?TT?HHHHHHHHHHHHHHHTS?H-HHHGGGEEEE----E????HHHHHHHHHHHHHTT???B-??---SSS??TTTS?S?T--------T??EEEEEE???SS??S?--------??GGGTT?G--GGEE?-----???TT?THHH--HHHHHHHTEEEEEEEEEEEETHHHH??GGGHHHHHHHHHHTT?EEEEEE??TTB??S-?SS?EEEEEEES??--SSBTTB???TTEEEEEE?TT?SEESS--SS?EE??HHHHHHHHHHHHHHHH?--------------??TTT?BT-----TTEEEEEHHHHHHTTT???TTTT????????? 3S1S|A PF02386.11_TrkH_seed 26 481 !Q:3,3|5,6|36,37|40,40|45,77|92,95|101,101|108,110|126,126|128,128|139,139|141,153|157,158|171,171|187,187|190,221|227,227|246,248|251,251|256,256|270,270|272,272|277,278|281,281|293,302|309,351|354,354|359,359|362,363|369,372|396,397|399,403|418,421|424,439|443,444|447,452|467,467|476,480 Q:0,2|4,4|7,35|38,39|41,44|78,91|96,100|102,107|111,125|127,127|129,138|140,140|154,156|159,170|172,186|188,189|222,226|228,245|249,250|252,255|257,269|271,271|273,276|279,280|282,292|303,308|352,353|355,358|360,361|364,368|373,395|398,398|404,417|422,423|440,442|445,446|453,466|468,475 HTT?S??TTHHHHHHHHHHHHHHHHHHHHTTHHHHS??TT?STTH---------------------------------HHHHHHHHHHHHTT????SSSSS-SGGGSS--?HHHHHHHHHHHHHHH-S?HHHHHHHHHH?S-------------SSS??HHHHHHHHHHHH-HHHHHHHHHHHHHTT?II--------------------------------IIITS?TTHHHHHHHHHHHTTTTT???SS?STTS?HHHHHHHHHHHHB?S?SSSS??SB?HHHHHHHHHHH----------HHHHHT------------------------------------------?SS?EETT-EE??HHHHH----HHHHHHHHHHHHHHHHHHHHHHH??S?----HHHHHHHHHHHHTT????SS?---------------GGG??HH------HHHHHHHHHHHHHH?HHHHHTTS????? 3PJZ|A PF02388.11_FemAB_seed 46 513 !Q:0,1|4,33|45,47|63,63|72,72|76,76|82,86|102,102|105,110|113,113|116,116|134,139|148,151|157,157|161,161|165,169|171,171|173,173|185,185|188,193|195,196|200,201|209,209|212,213|220,220|223,223|238,238|243,245|247,247|250,258|266,280|292,292|296,296|299,301|336,336|339,351|383,383|386,386|397,397|400,400|409,409|412,420|425,425|438,438|444,445|452,453|455,459|463,463|466,466|478,478|484,486|500,500|503,512 Q:2,3|34,44|48,62|64,71|73,75|77,81|87,101|103,104|111,112|114,115|117,133|140,147|152,156|158,160|162,164|170,170|172,172|174,184|186,187|194,194|197,199|202,208|210,211|214,219|221,222|224,237|239,242|246,246|248,249|259,265|281,291|293,295|297,298|302,335|337,338|352,382|384,385|387,396|398,399|401,408|410,411|421,424|426,437|439,443|446,451|454,454|460,462|464,465|467,477|479,483|487,499|501,502 ??HH------------------------------HHHHHHHTSTT-??TTSSHHHHHHHHHTT?EEEEEEEE?TTS?EEEEE-----EEEEEEETTTEEEEE?TT??----EE?TT?HHHHHHHHHHHHHHHHT------TTEEEEEE????EEEEE?TTS?EEE-----E?S?THHHHHHHHTT?EE?????-S??SSS??SEEEEEE?TT??HHHHHH-TS?HHHHHHHHHHHTSS?EEEE?-?G-GG---------HHHHHHH????-??????????HHHHHHHHHHH-GGG-EE--?EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH?TT?------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?SE-EEEEEEEEEE?SS?EEEEEEEE?GG---------GGGG?HHHHHHHHHHHH-HHHTT??EEEEEE??S??---STT?TT-HHHHHHHHTTT?EEEEE???EEEESSHHHHHHH-HH??-------? 1LRZ|A PF02390.12_Methyltransf_4_seed 19 294 !Q:3,9|11,23|27,27|30,57|65,65|68,68|89,89|104,105|111,113|121,122|126,126|131,132|135,135|144,159|182,182|196,223|231,247|254,254|258,265|283,285|293,293 Q:0,2|10,10|24,26|28,29|58,64|66,67|69,88|90,103|106,110|114,120|123,125|127,130|133,134|136,143|160,181|183,195|224,230|248,253|255,257|266,282|286,292 SGG-------G?----------??TTT?TT????????????---?????????????EEEEEET?TT?HHHHHHGGGSTTSEEEEEES?HHHHHHHHHHHHHH--HHSTT???TTEEEEE??TTT?HHHH??TT?EEEEEEES????????????????HHHHHHHHHHEEEEEEEEEEES?HHHHHHHHHHHHT----------------------------STTEEEE----------------?GGGGTT?TTG--------GGTTTSSHHHHHHHHTT???EEEEEEE? 3DH0|A PF02391.12_MoaE_seed 18 132 !Q:0,0|7,11|20,21|24,27|36,47|53,54|71,79|85,85|87,87|94,94|98,98|101,101|131,131 Q:1,6|12,19|22,23|28,35|48,52|55,70|80,84|86,86|88,93|95,97|99,100|102,130 ?EEEESS?--??HHHHHHHH??TT?--?EEEEEEEE????????-???EEEEE??HHHHHHHHHHHHHHHH---------TSSTT?E-EEEEEE?EEE?TT?EEEEEEEEESSHHHHHHHHHHHHHHHHHH? 1NVJ|A PF02395.11_Peptidase_S6_seed 9 942 !Q:0,11|14,14|17,17|19,19|30,30|33,34|37,37|40,40|44,44|47,48|58,58|60,62|67,67|71,78|89,89|92,93|101,101|105,107|113,113|115,115|120,120|131,132|134,138|142,143|155,156|158,159|164,166|169,172|174,175|177,178|185,185|189,190|197,197|210,211|218,219|228,228|232,233|238,238|241,243|246,247|250,251|258,258|261,263|265,266|268,268|274,274|277,284|288,288|290,291|294,294|297,297|319,319|324,325|332,333|354,359|364,366|378,380|387,392|394,398|404,406|409,422|428,429|436,437|439,439|447,447|450,450|453,454|458,458|469,471|473,473|479,479|483,483|486,486|491,492|494,495|498,498|511,512|516,518|523,523|530,531|533,534|538,538|542,542|544,544|548,548|551,551|563,563|566,566|571,571|574,576|581,581|584,585|590,591|602,604|608,608|614,625|629,631|635,639|642,642|644,646|649,654|657,657|659,659|661,662|665,667|677,677|680,681|685,687|692,694|720,722|724,726|731,732|736,740|747,747|752,752|757,757|762,762|776,777|780,785|789,791|793,795|798,800|802,802|806,809|812,812|815,815|826,826|829,829|834,834|847,847|850,850|857,857|860,861|863,863|868,868|871,871|873,875|880,880|882,884|886,886|893,894|900,900|904,904|907,907|919,919|923,923|926,926|931,931|938,938|941,941 Q:12,13|15,16|18,18|20,29|31,32|35,36|38,39|41,43|45,46|49,57|59,59|63,66|68,70|79,88|90,91|94,100|102,104|108,112|114,114|116,119|121,130|133,133|139,141|144,154|157,157|160,163|167,168|173,173|176,176|179,184|186,188|191,196|198,209|212,217|220,227|229,231|234,237|239,240|244,245|248,249|252,257|259,260|264,264|267,267|269,273|275,276|285,287|289,289|292,293|295,296|298,318|320,323|326,331|334,353|360,363|367,377|381,386|393,393|399,403|407,408|423,427|430,435|438,438|440,446|448,449|451,452|455,457|459,468|472,472|474,478|480,482|484,485|487,490|493,493|496,497|499,510|513,515|519,522|524,529|532,532|535,537|539,541|543,543|545,547|549,550|552,562|564,565|567,570|572,573|577,580|582,583|586,589|592,601|605,607|609,613|626,628|632,634|640,641|643,643|647,648|655,656|658,658|660,660|663,664|668,676|678,679|682,684|688,691|695,719|723,723|727,730|733,735|741,746|748,751|753,756|758,761|763,775|778,779|786,788|792,792|796,797|801,801|803,805|810,811|813,814|816,825|827,828|830,833|835,846|848,849|851,856|858,859|862,862|864,867|869,870|872,872|876,879|881,881|885,885|887,892|895,899|901,903|905,906|908,918|920,922|924,925|927,930|932,937|939,940 -----------?EE?SS-S?HHHHHHHHHT?TT??TT?BS?EEE?TT??EEEESSSTT?B???GGGB?TTT??-----?EEEETTEEEB?TT??STTSEEE?SSS???TTSTT?S?BTTB?GGGGEEEEEE??B?????SSS??SHHHHHHHHHT??B??EESS???SS????B??S??STTGGG?TTT??EEEEEE?SSEEEEEEEEEE??EETTEE??EEEEEEEE?TTS??EEEB?SS---EE??ST--TEEEEE?TT???S--S?TTGGG-SS--------TTB?B??TT?TT?EEEEEETTTTEEEEEEEEEEE?HHHH??EEEEEE??HHHHHHHHHHHEEEEEEEEE------EEEE---EEEETTEEEEE---ETTEEE------E?????TTSSS---HH--------------HHHHT??EEEEEE--E-EEEEESS?EE?TT??EEE?SEEEEEESST---T?BEESS?EEE?TT?EEEE??B??TT?EEEEESSSEEEE??BEE???EEEE?SEEEEE??B??TTS?EES?S?EEE?SS?EEEEESSTTSS?GG-GEEE?TT--?EEEE?TT??EEES??EESSTTEEEE???TTS?EEEEE??----??????GGG???EEE???-?SS?T---TS???-??TT?S?E--EE---TTTTEEEEE?TT??TTS???SSTT???SSEEEEESSHHHHHHHHHHHHHHHT???B?--SEES??TTS-????EEEEEE?SSTT?EEEE?SEEE?SSEEEEEESEEEE??EE??????TTS???S???GG---G?GGG????TT?EE?EEEEEEEEEE?TT?EEEE?TTEEEEEEEEEE?TT?EEEESB?TT--S?EEEE?TT-T?-?EEEE?S???H-HHHTTS??EEEES?EEE?TT?EEEESBEEEES?EEE?TT?EEEE?TTEEEE?SS? 3AK5|A PF02401.13_LYTB_seed 13 354 !Q:3,3|6,6|8,9|23,23|28,28|30,31|37,37|41,41|49,49|61,68|72,82|85,85|90,90|93,95|107,107|112,114|132,132|139,139|142,142|152,176|180,180|185,185|193,195|197,197|206,206|209,210|225,225|228,228|230,239|242,242|244,245|262,262|264,264|270,271|274,274|289,290|300,316|318,319|326,326|328,328|335,335|338,339 Q:0,2|4,5|7,7|10,22|24,27|29,29|32,36|38,40|42,48|50,60|69,71|83,84|86,89|91,92|96,106|108,111|115,131|133,138|140,141|143,151|177,179|181,184|186,192|196,196|198,205|207,208|211,224|226,227|229,229|240,241|243,243|246,261|263,263|265,269|272,273|275,288|291,299|317,317|320,325|327,327|329,334|336,337|340,353 EEE?SS?S??HHHHHHHHHHHHH-HHHH?S-?EEEES?SSS?HHHHHHH-HHHTEEEESSG--------GGS?----------TT?EEEE?TT???HHHHHHHHHTT?EEEE???HHHHHHHHHHHHHHHTT?EEEEES?TT?HHHHHHHTT???----------------------TTS?EEEE?SHHHHHH???S?TTSEEEEE?TT??HHHHHHHHHHHHHH?TT?B?--------?SS?S??HHHHHHHHHHHHHHTT?S-EEEEE??TT?HHHHHHHHHHHHTT?-EEEEESSGG-----------------G??HHHHTT?S-EEEEEE?TT??HHHHHHHHHHHHHT 3KE8|A PF02403.17_Seryl_tRNA_N_seed 89 122 !Q:0,2|9,13|25,28|73,78|80,80|101,101|118,121 Q:3,8|14,24|29,72|79,79|81,100|102,117 ???HHHHHH----?HHHHHHHHTTT?---GGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTGGGSS?-----S?TTTSTTHHHHHHHHHHHHHH-HHHHHHHHHHHHHHTS???? 3QO5|A PF02404.10_SCF_seed 4 288 !Q:0,35|47,47|50,51|56,57|64,64|88,88|90,91|94,98|118,134|139,139|157,160|165,166|168,287 Q:36,46|48,49|52,55|58,63|65,87|89,89|92,93|99,117|135,138|140,156|161,164|167,167 ????????????????????????????????????HHHHHHHHHHS?TT??EEEE??TTTTTS?GGGTHHHHHHHHHHHHHHHHTTS?S??SS---??HHHHHHHHHHHHHHHHHHT???????-?????????EEEE?HHHHHHHHHHHHHTTTS-???SSSS??S??-????????????????????????????????------?????????????????????????????????????????????-????????????--??????????????????? 1EXZ|A PF02406.12_MmoB_DmpM_seed 40 100 !Q:0,5|9,11|26,31|35,42|45,45|47,50|57,57|66,66|74,74|83,83|86,87|90,91|94,94 Q:6,8|12,25|32,34|43,44|46,46|51,56|58,65|67,73|75,82|84,85|88,89|92,93|95,99 ??????EEE--?SSHHHHHHHHHHHH------SSS--??????SS?B????SSEEEE?HHHHHHHH-HTGGGHH-HHHHSEEE?SS??EE?-SS?EEEES 2INP|L PF02407.11_Viral_Rep_seed 19 93 !Q:2,2|10,11|14,15|17,17|25,25|38,40|44,45|56,57|59,59|70,70|76,79|81,81 Q:0,1|3,9|12,13|16,16|18,24|26,37|41,43|46,55|58,58|60,69|71,75|80,80|82,92 BS?EEEEEES??HH--H-HHHHHTS?GGGEEEEEEEEE???TTS??EEEEEEEESS?-B?HHHHHHHHTT-TSEEE???-S?HHHHHHHHHTT 2HWT|A PF02410.10_Oligomerisation_seed 165 163 !Q:13,14|22,22|25,30|33,39|56,61|70,71|74,76|78,83|85,89|93,93|96,125|129,131|138,139|141,141|152,152|161,162 Q:0,12|15,21|23,24|31,32|40,55|62,69|72,73|77,77|84,84|90,92|94,95|126,128|132,137|140,140|142,151|153,160 HHHHHHHHHHHTT?-EEEEEEE?BT------TB---????EEEEEEESSHHHHHHH------HHHHHHHH--HH---T------T-????EEE-ST------------------------------TTT---SEEEEE?-S-SEEEEEEETT?GGGTSTTT?? 2O5A|A PF02412.13_TSP_3_seed 11 40 !Q:0,1|8,8|12,18|21,21|25,25|29,29|35,36|39,39 Q:2,7|9,11|19,20|22,24|26,28|30,34|37,38 ??TTSSSB?TTT??--???TT?SSS?GGG?SSTTS??TT? 3FBY|A PF02416.11_MttA_Hcf106_seed 12 83 !Q:1,1|17,17|45,82 Q:0,0|2,16|18,44 S?HHHHHHHHHHHHHHS?TTTHHHHHHHHHHHHHHHHHHHHHHHH?------------------------------??????? 2LZS|A PF02419.12_PsbL_seed 14 37 !Q:0,3|6,8|11,12|36,36 Q:4,5|9,10|13,35 ????TT???EE??HHHHHHHHHHHHHHHHHHHHHHH? 3PRR|L PF02420.10_AFP_seed 9 12 !Q:4,4|6,7|10,10 Q:0,3|5,5|8,9|11,11 EEES?S??TT?S 1EZG|A PF02421.13_FeoB_N_seed 147 190 !Q:6,6|21,22|24,24|27,40|46,48|50,55|58,58|62,62|67,75|77,77|79,82|85,86|100,104|107,109|120,120|136,138|145,145|154,158|168,168|170,170|174,174 Q:0,5|7,20|23,23|25,26|41,45|49,49|56,57|59,61|63,66|76,76|78,78|83,84|87,99|105,106|110,119|121,135|139,144|146,153|159,167|169,169|171,173|175,189 EEEEEE?STTSSHHHHHHHHH??S-SS?????????--???EEEEE---E------TT-EEE-EEEE????-----S?S----SS--SSHHHHHHHHHHH-----HH?-?SEEEEEEETT?HHHHHHHHHHHHHTT-??EEEEEE?HHHHHHTT-????HHHHHHHHT-S?EEE?BGGGTBSHHHHHHHH 4AWX|A PF02423.10_OCD_Mu_crystall_seed 11 348 !Q:0,1|6,6|14,15|18,18|35,38|41,44|49,49|52,56|68,70|80,80|87,87|90,90|92,93|100,100|104,106|113,113|134,134|137,138|144,145|161,164|170,170|185,188|192,193|197,198|211,214|217,224|226,226|230,231|234,234|239,239|241,242|246,248|250,250|262,262|264,264|283,293|295,295|312,316|319,319|325,328 Q:2,5|7,13|16,17|19,34|39,40|45,48|50,51|57,67|71,79|81,86|88,89|91,91|94,99|101,103|107,112|114,133|135,136|139,143|146,160|165,169|171,184|189,191|194,196|199,210|215,216|225,225|227,229|232,233|235,238|240,240|243,245|249,249|251,261|263,263|265,282|294,294|296,311|317,318|320,324|329,347 ??EEEE?HHHHHTS??HH-HHHHHHHHHHHHHHTT---?SB????EEEE?SS----?EEEEEEEEETT---EEEEEEEEE?TTTGGG-TS?S??EEEEEE?TTT?-?EEEEEE?HHHHHHHHHHHHHHHHHHHS?TT??EEEEE??SHHHHHHHHHHHHHS?-??EEEEE?SSHHHHHHHHHHHH----HTT??EEE??HHHHTSSSEEEE????SS------??B?GGG??TT?EEEE?S??STT???B?HHHHHTEEEEE-S?HHHHHHHSTTHHHHHTTS-----------S?STTEEEEHHHHHHTSS?????SS?EEEEE????HHHHHHHHHHHHHHHHHHT 1OMO|A PF02424.10_ApbE_seed 245 466 !Q:8,8|10,11|13,14|16,17|20,22|31,35|37,38|40,41|44,44|50,51|66,69|71,71|74,75|80,80|84,90|92,92|96,115|120,135|141,144|152,158|160,160|163,163|173,177|193,193|195,196|200,209|211,214|221,221|228,229|232,235|240,248|250,258|262,316|318,319|322,328|331,331|333,335|341,342|344,365|367,367|369,371|377,381|383,383|391,392|397,400|403,407|417,418|421,426|430,430|438,441|444,453|455,455|457,462 Q:0,7|9,9|12,12|15,15|18,19|23,30|36,36|39,39|42,43|45,49|52,65|70,70|72,73|76,79|81,83|91,91|93,95|116,119|136,140|145,151|159,159|161,162|164,172|178,192|194,194|197,199|210,210|215,220|222,227|230,231|236,239|249,249|259,261|317,317|320,321|329,330|332,332|336,340|343,343|366,366|368,368|372,376|382,382|384,390|393,396|401,402|408,416|419,420|427,429|431,437|442,443|454,454|456,456|463,465 HHHHHHHH?S--S--S--TT---SHHHHHHH???-?S-?E--EE?HHHHH--HHHHHHHHHHHTTT---?S?TT?-HHHH-HHH-------T?STT??--------??????---?TTHH----------------HHHTT--??GGGEEEE-------E?SS?EEEEESSTT?????HHHHHHHHHHHHHHH-H--HHT----------T??-?EEEEET-TEEEEE--SB?---SSSS---------B-------??EEE--?--?--?---?-------------------------????----------???E--EE-----??BT-E---EEEEE--E-??????-?--??--???????B?T---TTSSB??---S?EEEEEEE--ESSH----HH-----HHHHHHHHH--HH-?----HHH-HHHHHHH----HT---------?E-E------EEE 4IFX|A PF02425.10_GBP_PSP_seed 3 23 !Q:0,7|21,22 Q:8,20 ????????TTEEEETTTEEEE?? 2EQT|A PF02426.11_MIase_seed 7 94 !Q:0,0|9,11|14,15|45,47|60,60|88,89|92,93 Q:1,8|12,13|16,44|48,59|61,87|90,91 ?EEEEEEEE???TT??HHHHHHHHHHHHHHHHHHHHTTSEEEEEE---ETTSSEEEEEEE?SSHHHHHHHHHTSTTGGGEEEEEEEEE??TT?? 3ZO7|A PF02427.12_PSI_PsaE_seed 25 70 !Q:0,1|4,4|9,10|13,13|18,18|26,28|30,30|32,32|34,35|40,40|43,44|46,46|51,56|61,61|68,69 Q:2,3|5,8|11,12|14,17|19,25|29,29|31,31|33,33|36,39|41,42|45,45|47,50|57,60|62,67 ??TT?EEEE??TT?TTBT?EEEEEEE???T-T?S??EEEE?SS??S?SSTT??????EEEE?GGGEEE?? 1PSF|A PF02428.10_Prot_inhib_II_seed 10 54 !Q:0,8|16,18|20,20|23,24|30,32|37,37|53,53 Q:9,15|19,19|21,22|25,29|33,36|38,52 ?????????TTEEEEE???S?SS--SSSSS???SSSS?TTSEEEETTTEEEEE? 1YTP|A PF02429.10_PCP_seed 9 154 !Q:0,0|2,2|22,22|25,25|27,30|35,36|39,41|60,60|76,76|79,81|85,87|106,106|121,123|135,135 Q:1,1|3,21|23,24|26,26|31,34|37,38|42,59|61,75|77,78|82,84|88,105|107,120|124,134|136,153 ?H-HHHHHHHHHHHHHHHHHHS?TT?S----GGGS??TT?-?HHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHH-HT??-TTS???HHHHHHHHHHHHHHHTTS?HHHHHHHHHHHHHH-??THHHHHHHHTS?HHHHHHHHHHHHHHHHHH 2X21|M PF02430.10_AMA-1_seed 7 555 !Q:0,433|442,443|446,447|450,452|455,458|461,463|465,554 Q:434,441|444,445|448,449|453,454|459,460|464,464 ????????????????????????????????????????????????????????-????????????????????-----------------------????????????????-?????????????????????????????????????????????????????????????????--???-????????????????????????????????????????????????--???????????????????????????????-??????????????????????????????-??????????????????????????????????????????????????????????-????????????????-----------------------------?????????????????????????-???EESSSGGG??SS??EE???SS??-?EE???B??????????????????????????????????????????????????????????-------??????-------------?????? 2Y8T|A PF02431.10_Chalcone_seed 60 358 !Q:1,1|4,4|6,6|8,8|12,38|46,64|75,75|87,87|90,98|110,111|114,149|154,154|164,165|168,170|180,181|204,231|245,247|249,250|253,254|257,257|260,260|267,269|273,273|275,280|283,283|291,306|309,309|315,315|318,325|336,336|340,340|342,342|355,355 Q:0,0|2,3|5,5|7,7|9,11|39,45|65,74|76,86|88,89|99,109|112,113|150,153|155,163|166,167|171,179|182,203|232,244|248,248|251,252|255,256|258,259|261,266|270,272|274,274|281,282|284,290|307,308|310,314|316,317|326,335|337,339|341,341|343,354|356,357 E?SE-E-E?TTT?-------------------------?EEEEEEE-------------------EEEEEEETTE-EEEEEEEEEEE?TT---------HHHHHHHHHTT??HH------------------------------------HHHH?HHHHHHHHH?-SS--?EEEEEEESS?-EEHHHHHHHHTTTHHHHHHHHT?-------------------??------HHHHHHHHHHHHH---H--TT?-EE?TT?EEEEEE--?TTS-E------EE-EEEESSS???-------------SS?SEEEE?HH--------HHHHHHHHHH-STT?S?HHHHHHHHHHHH-HH 4DOO|A PF02432.10_Fimbrial_K88_seed 17 282 !Q:0,0|12,15|18,24|38,38|49,50|52,52|54,55|62,62|65,65|67,69|75,77|83,83|85,85|89,89|92,93|95,102|104,104|114,115|119,119|135,139|143,143|146,146|155,157|167,169|173,174|190,191|203,203|206,207|212,217|219,220|222,222|224,229|233,233|239,244|250,250|253,253|262,264|266,267|281,281 Q:1,11|16,17|25,37|39,48|51,51|53,53|56,61|63,64|66,66|70,74|78,82|84,84|86,88|90,91|94,94|103,103|105,113|116,118|120,134|140,142|144,145|147,154|158,166|170,172|175,189|192,202|204,205|208,211|218,218|221,221|223,223|230,232|234,238|245,249|251,252|254,261|265,265|268,280 ?EEEEEEEEEEE???-TT???????SSSEEEEEEEGGG?BTTTTEEEEE??S?E--EEEEEE?SS?B???SSSSS???EEEEE-E?TTS?EE??B????????S?EEEEEEEEE-?TTS?EEEEEEEEEEEEEEE-----EEE?SS?SEEEEEEB???STTSTTBTS-??SSS??SBHHHHHHHHHHHTS??HHHHHHHHHHH?TT??EEEE-----?B--S?B??????SSS?EEEEE------EEEEE?TT?EEEEEESS???S-?EEEEEEEEEEEEE? 3GEW|A PF02433.10_FixO_seed 56 340 !Q:0,3|6,6|32,32|37,37|39,94|97,101|120,125|135,138|141,143|150,150|153,156|159,159|162,164|167,167|170,170|173,173|183,183|191,196|202,202|204,218|232,242|244,249|252,265|277,321 Q:4,5|7,31|33,36|38,38|95,96|102,119|126,134|139,140|144,149|151,152|157,158|160,161|165,166|168,169|171,172|174,182|184,190|197,201|203,203|219,231|243,243|250,251|266,276|322,339 ????SS?HHHHHHHHHHHTTHHHHHHTHHHHH?STTT-S??------------------------------------------------------TT?????HHHHHHHHHHHHHTGGGT??????SSHHHHHHH----SS???GGGGTT?SS????SB?SS???TT?TT-TS?HHHHHHHHH?HHHHSTT??????THHHH?B-??-----------?TTHHHHHHHHHHT-----------T????--HH--------------HHTTSHHHHTT?--------------------------------------------BHHHHHHHHHTTTTTTGG 3MK7|B PF02434.11_Fringe_seed 27 375 !Q:0,3|7,8|15,16|46,47|54,58|66,87|102,106|119,119|131,131|135,136|140,140|143,187|190,197|201,211|215,232|241,249|252,253|258,258|262,263|270,270|284,286|290,290|293,295|299,299|303,304|311,311|313,340|344,344|349,351|356,361|363,365|367,367|371,371 Q:4,6|9,14|17,45|48,53|59,65|88,101|107,118|120,130|132,134|137,139|141,142|188,189|198,200|212,214|233,240|250,251|254,257|259,261|264,269|271,283|287,289|291,292|296,298|300,302|305,310|312,312|341,343|345,348|352,355|362,362|366,366|368,370|372,374 ????GGG--EEEEEE??GGGTTTTHHHHHHTGGGGSGGGEEEEESS??HHHHHH-----HGGGEEE???????????---------??HHHHHHHHHHHHHT?----SEEEEEETTEEE?HHHHHHHHTTS?TTS??EEE?EE???????????????-----------------------???????EE-------?GGG----------?EEE------------------EHHHHHHH---------HH--HHTT?TTS??TTTTTS?HHHHHHHHHHHTT???EEE?TT???SSS?GGG??TTTGGG?S----------------------------EEE?EEET---TEEE??????S---S?TTT?TTS 2J0A|A PF02435.11_Glyco_hydro_68_seed 11 536 !Q:2,2|6,9|12,13|25,25|28,29|33,34|36,36|41,45|48,50|52,52|54,58|60,60|70,70|73,75|91,91|95,108|110,111|115,115|119,119|130,131|136,136|139,141|149,149|161,162|180,180|194,194|198,198|204,205|219,219|222,222|236,240|245,246|250,250|253,272|280,280|286,286|298,298|300,308|310,314|319,321|324,324|327,329|341,342|356,359|369,369|375,376|395,395|400,408|411,414|425,425|429,430|438,438|443,443|445,446|450,453|457,458|462,462|477,479|491,493|495,499|505,505|507,507|520,520|529,530|533,535 Q:0,1|3,5|10,11|14,24|26,27|30,32|35,35|37,40|46,47|51,51|53,53|59,59|61,69|71,72|76,90|92,94|109,109|112,114|116,118|120,129|132,135|137,138|142,148|150,160|163,179|181,193|195,197|199,203|206,218|220,221|223,235|241,244|247,249|251,252|273,279|281,285|287,297|299,299|309,309|315,318|322,323|325,326|330,340|343,355|360,368|370,374|377,394|396,399|409,410|415,424|426,428|431,437|439,442|444,444|447,449|454,456|459,461|463,476|480,490|494,494|500,504|506,506|508,519|521,528|531,532 EE?TTS-???EE??HHHHTHHHHHS?TT??TTS??S?GGGB?????TT???S?T-----T?EEEEEEEEE?TT-??BEEETTEEEEEEEEE?TTS--------------S??GGG?GGG?EEEEEEEESS??GGGS?TT???EEEEESS?TTGGGGGSTTS??SEEEEEEEEEEESSTTS?EEEEEEEEEEEEE?TTS?EEEEE--EEEEEEEEEEEEE?SS?EEEEEEEEEEEEE-?-??SSSB??TTT?TT-----------------???EEEEEEE?TTSTT?EEEEEEEEBSS?T---------T?????HHHH???TT?TT???HHHHHHTTGGG??EEEEEEEESSTTS--??EEEEEEEEE?TTTBS??EEEEEEEETTEEEEEEEE?GGGB?--------TT????SEEEEEEESS-SEE??EESTTTT?EEEE?S??SSS????SSS??SSS?TTTTSEEEEEEEGG---GEEEEEEEESS---S----?EEEEE?B?EEEEEETTEEEE?TTSTBTTB??BT??? 3OM4|A PF02436.13_PYC_OADA_seed 139 265 !Q:4,6|9,9|22,22|43,45|65,79|84,85|89,89|93,95|107,109|112,114|123,123|126,133|135,135|141,144|157,161|164,183|208,209|214,214|218,235|239,241|248,250|256,256 Q:0,3|7,8|10,21|23,42|46,64|80,83|86,88|90,92|96,106|110,111|115,122|124,125|134,134|136,140|145,156|162,163|184,207|210,213|215,217|236,238|242,247|251,255|257,264 HHHH???SS?SSSTTTTTGGGT?STTTHHHHHHHHHHHTTTTS???STTSHHHHHHHTTTTTTTT?-------------?TTHH--HHS?SSS???HHHHHHHHTTT???SS???HHHHHHHH-TT--???-??S?HHHHS????HHHHHHHTTTTS-----SS-?---?-------------?HHHHHHHHHSHHHHHHHHHHHHHS??GGGS?HHH------------------HHH???TTEEEE---EEEET-TEEEEEEE 3HO8|A PF02437.12_Ski_Sno_seed 10 132 !Q:0,28|30,33|36,37|73,74|87,89|92,93|107,107|110,113|130,131 Q:29,29|34,35|38,72|75,86|90,91|94,106|108,109|114,129 ---------------------------??G----GG??EEEEETTEEEEEEEETTEEEEEHHHHHHHHTTTTT??HHHHHHHHHHTT???EE??HHHHHHHHHHTSS?TT????EEEEHHHHHHHHHHHH?? 3EQ5|A PF02441.14_Flavoprotein_seed 143 290 !Q:7,7|15,15|24,44|47,48|51,51|55,55|59,59|64,64|67,98|101,101|103,149|152,152|154,154|161,179|185,186|192,192|196,198|207,207|218,220|222,222|228,247|251,252|254,263|266,272|276,278|281,282 Q:0,6|8,14|16,23|45,46|49,50|52,54|56,58|60,63|65,66|99,100|102,102|150,151|153,153|155,160|180,184|187,191|193,195|199,206|208,217|221,221|223,227|248,250|253,253|264,265|273,275|279,280|283,289 EEEEEEE?SSGGGGT-HHHHHHHH?---??------??-------EE--EE-EEE?TGG-GGSS?GG--------------------------------GS?S?----------------------------------------------EE?H-HHHHHT?------------------SSTTS??HHHHH-HTT--?SEEEEEEE?HHHHHHHHTT???S-HHHHH--------------------HHT??T----------TS?-?--?-EEE???HH--HHTSSTH 1MVL|A PF02442.12_L1R_F9L_seed 32 241 !Q:0,3|5,6|10,17|36,37|42,45|67,67|69,69|71,71|76,78|89,89|95,95|104,109|117,121|123,123|129,129|140,140|148,150|153,155|165,166|170,171|179,179|201,206|209,240 Q:4,4|7,9|18,35|38,41|46,66|68,68|70,70|72,75|79,88|90,94|96,103|110,116|122,122|124,128|130,139|141,147|151,152|156,164|167,169|172,178|180,200|207,208 -???T--HHH--------HHHHHHHHHHHHHHHHHH??BTTS??--SSEEEEEEEEEEESEEEEEEE?B?S?HHHH---HHHHHHHHHH-HHHHS?HHHHTTHH------HHHHHHT?????T-THHHH-HHHHHHHHHH-HSHHHHT???SE---EEEEEEEEE??SSS?-EEEEEEE?SSHHHHHHHHHHHHHHHTTTT------TT???-???????--------------------- 2I9L|I PF02443.10_Circo_capsid_seed 12 287 !Q:0,26|29,46|48,49|64,72|74,75|84,84|90,90|93,115|124,124|140,140|142,142|145,147|149,150|157,157|161,167|174,174|179,179|182,182|190,191|197,198|201,201|203,203|207,211|213,214|218,220|223,224|227,248|258,260|263,268|285,286 Q:27,28|47,47|50,63|73,73|76,83|85,89|91,92|116,123|125,139|141,141|143,144|148,148|151,156|158,160|168,173|175,178|180,181|183,189|192,196|199,200|202,202|204,206|212,212|215,217|221,222|225,226|249,257|261,262|269,284 ???????????????????????????GG------------------G??EEEEEEEEEEEEEE?---?????S??EEEEEEEE?GGGTS?EE-----------------------ETTEEESS?EEEEEEEEEEEEEEE?S?TT?-?S??EEEEEE?SSS???--??EEEESS?TTTT?TT?EEEETTT??EEEEE??EE?S?TTT?????S-?GGG???EE??SS------------------????EEEEEEEEE??-SS?-----EEEEEEEEEEEEEEEE?? 3R0R|A PF02445.11_NadA_seed 144 464 !Q:10,11|23,23|27,27|31,31|36,40|51,53|62,62|73,75|80,88|91,91|94,102|105,106|111,114|121,124|127,132|134,134|142,142|148,151|153,153|158,158|169,169|171,174|176,178|181,181|187,187|195,224|229,231|234,265|270,271|275,276|281,282|285,285|295,296|299,299|303,303|307,310|317,317|319,327|329,330|337,337|340,348|353,353|363,364|366,376|381,391|398,402|412,417|420,437|440,446 Q:0,9|12,22|24,26|28,30|32,35|41,50|54,61|63,72|76,79|89,90|92,93|103,104|107,110|115,120|125,126|133,133|135,141|143,147|152,152|154,157|159,168|170,170|175,175|179,180|182,186|188,194|225,228|232,233|266,269|272,274|277,280|283,284|286,294|297,298|300,302|304,306|311,316|318,318|328,328|331,336|338,339|349,352|354,362|365,365|377,380|392,397|403,411|418,419|438,439|447,463 HHHHHHHHHH--HTEEEEEETTS?HHH-HHH?SEEE----?HHHHHHHTTS-??SSEEEEES?HHHHHHHHHH-?-TTSE---------EE?SS?-???????TT??HHHH----HHHHHH?---TT------S?EEEESSS?HHHHT----T?SEEE?TTTHHHHHHH-S----S?--SE-EEEES?HHHHHHH------------------------------HHHH-??EE--------------------------------EESS?-SSS??TGGG??HH-HHHHHHTSS-?SS?EEE?TTS---?HHHHTT?S--------?B??HHHHHH?TT?--??-?-?EEES?HHHHHHHGG--G?----??-???EESS---------?-SSSSTT?????HHHHHHHHH------HT?-----------------SB-????--HHHHHHHHHHHHHHHHH 2QS0|A PF02446.12_Glyco_hydro_77_seed 14 722 !Q:0,1|6,7|10,11|14,15|32,36|40,43|45,45|47,47|50,58|64,64|67,69|73,74|84,106|110,111|134,135|150,152|163,164|174,181|186,190|197,197|236,237|240,240|250,251|260,260|265,265|267,267|271,272|277,277|280,282|285,285|288,288|291,295|297,297|320,320|340,356|358,358|364,364|369,370|372,438|451,514|516,517|521,522|525,527|539,540|552,552|555,555|563,564|567,568|574,575|579,580|589,609|624,624|626,628|647,647|657,660|664,665|668,675|677,677|679,680|683,683|687,688|691,691|693,695|698,705|707,707 Q:2,5|8,9|12,13|16,31|37,39|44,44|46,46|48,49|59,63|65,66|70,72|75,83|107,109|112,133|136,149|153,162|165,173|182,185|191,196|198,235|238,239|241,249|252,259|261,264|266,266|268,270|273,276|278,279|283,284|286,287|289,290|296,296|298,319|321,339|357,357|359,363|365,368|371,371|439,450|515,515|518,520|523,524|528,538|541,551|553,554|556,562|565,566|569,573|576,578|581,588|610,623|625,625|629,646|648,656|661,663|666,667|676,676|678,678|681,682|684,686|689,690|692,692|696,697|706,706|708,721 ??GGGS??SS--SS??SSHHHHHHHHHHHHTT---??EEE????S?B?TT??-------TTSBS?SS???GGG??SHHHHHTTS??------------???--????SSB??HHHHHHHHHHHHHHHHHHHHHH??HHHHHHHHHHHHHH---HHHHHHHHHH--HHHHHHTTT------??GGGS----?HHHHTT?HHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHH--TT?EEEEEEESS??SSSHHHHH?GGGB?B?TTS-?BSEE?EE???SS?SS?EE?????B?HHHHHHTTTHHHHHHHHHHHHH?SEEEEETGGGGTEEEEEET-----------------T?SSSTT?EEEE??H-------------------------------------------------------------------HHHHHHHHHHHS----------------------------------------------------------------S??EEE??TT???HHHHHHHHHTT??EEEEGGGSSSS?TT?TTSGGGS?-TT??EEEES??TTS??HHHHHHHS-?-------------------HHHHHHHHHHHHHT-T???SSGGGHHHHHHHHHHHSS?SEEEEEHHH----HTT??GG--------G?S??TT?SSS--TT?B???TT-------?S?HHHHHHHHHHHHHT 1FP8|A PF02449.10_Glyco_hydro_42_seed 28 461 !Q:1,2|7,7|9,10|25,26|31,31|34,34|39,39|45,47|50,56|69,69|75,75|77,84|88,89|96,96|101,101|103,103|107,107|109,110|115,118|121,121|125,125|137,141|148,148|156,156|167,169|178,192|201,209|212,212|227,229|235,237|239,239|241,241|243,251|253,255|277,277|289,289|293,293|296,296|299,307|310,310|326,326|331,331|336,338|349,350|365,366|370,371|375,375|379,380|382,384|387,387|391,395|411,411|413,413|418,418|420,421|423,424|433,434|437,437|441,442|444,444|460,460 Q:0,0|3,6|8,8|11,24|27,30|32,33|35,38|40,44|48,49|57,68|70,74|76,76|85,87|90,95|97,100|102,102|104,106|108,108|111,114|119,120|122,124|126,136|142,147|149,155|157,166|170,177|193,200|210,211|213,226|230,234|238,238|240,240|242,242|252,252|256,276|278,288|290,292|294,295|297,298|308,309|311,325|327,330|332,335|339,348|351,364|367,369|372,374|376,378|381,381|385,386|388,390|396,410|412,412|414,417|419,419|422,422|425,432|435,436|438,440|443,443|445,459 E??GGGS?H--HHHHHHHHHHHHHT??EEEE?TT?HHHH?SBTTB???HH-------HHHHHHHHHTTT?EEEEE?S--------TTS??HHHHHH?GGGS?B?TTS?B??SSSS????TT?HHH-HHHHHHHHHHH-----HHHHTT?TTEEEEE?SSSTTTTTTS???SHHHHHHH---------------HHHHHHHH---------SS-HHHHHHHHTTTGGG???SSGGG???S?S?S---------S???HHHHHHHHHHHHHHHHHHHHH-HHHHHHHHSTT?EEE?EE?TT-------??SS?HHHHGGGSSSEEEEE?HHHH-HHHS???HHHHHHTTTT??TTHHHHHHHHHHHH--TTT?-EEE-EEE??S-??SS-SSS?????TTHHHHHHHHHHHTT?S?EEEE?S--B??SSSTTTTS??SB?TTS-?B?HHHHHHHHHHHHHHT? 5BCA|A PF02452.12_PemK_seed 306 216 !Q:0,0|9,15|17,21|25,32|34,34|39,46|49,49|51,51|53,54|58,58|61,68|78,78|80,83|85,85|87,87|89,89|92,103|110,111|113,115|118,119|122,122|124,139|141,141|154,154|157,159|162,165|167,167|169,176|181,199|207,207 Q:1,8|16,16|22,24|33,33|35,38|47,48|50,50|52,52|55,57|59,60|69,77|79,79|84,84|86,86|88,88|90,91|104,109|112,112|116,117|120,121|123,123|140,140|142,153|155,156|160,161|166,166|168,168|177,180|200,206|208,215 ?TTEEEEEE?-----?S--??-TTS------??S-EEEE--------EE?S?H--HHH-HH--?-----SEEEEEEEE-S----S?S-S?SS------------TTEEEE?-H---HH--HT?S----------------S?EEEEEEEEEEEE-GG---GE----E-E--------EEEE---------------??--HHHHHHH-HHHHHHHT 1NE8|A PF02455.11_Hex_IIIa_seed 13 594 !Q:15,15|33,34|58,59|65,65|81,81|83,84|87,87|108,110|113,114|118,118|121,121|126,127|129,130|143,143|146,162|176,177|182,182|185,185|202,202|220,220|223,223|234,594 Q:0,14|16,32|35,57|60,64|66,80|82,82|85,86|88,107|111,112|115,117|119,120|122,125|128,128|131,142|144,145|163,175|178,181|183,184|186,201|203,219|221,222|224,233 HHHHHHHTTTTTTSS?GGGGGTSHHHHHHHTTS??SHHHHHHHHTTTHHHHTHHHHHH--HHHHH?TTHHHHHHHHHHHHS?S??SS?SHHHHHHHHHHHHHHHHSTT-??EE??SSS?EE?SSTT?-S??EEHHHHHTTTSS?TT???????-?????????HHHHHHHHHSSSS??STTS?TT?HHHHHHHHHHHHHHHH-HHHHHHHHHHTTSSTTS?TT-HHHHHHHHHH??????????-???????????????????????????????-???????????????????????????????????????????????????????????????????-???--????????????????????????????????????????????????????????????????????-----------------------------------?????????????????????????--------???????????????????----??????????????------???????????????????????????????????------------????????--??--????- 3IYN|N PF02457.11_DisA_N_seed 190 152 !Q:12,13|19,23|26,27|29,30|33,33|35,36|40,51|56,57|67,67|70,71|75,75|84,84|94,101|104,106|108,108|111,112|126,126|128,128|134,134|138,139|146,147 Q:0,11|14,18|24,25|28,28|31,32|34,34|37,39|52,55|58,66|68,69|72,74|76,83|85,93|102,103|107,107|109,110|113,125|127,127|129,133|135,137|140,145|148,151 HHHHHHHHHHHT??EEEEE---??SS??T--TT?B-?SEE------------EEEE??HHHHHHHTS-TT--STT?SSEEEEET-TEEEEEEEB??????--TT---S?TT??HHHHHHHHHHTTS-S?EEEEE?TTT??EEEEET--TEEE 3C1Y|A PF02458.10_Transferase_seed 11 525 !Q:0,1|11,12|15,18|20,22|25,27|31,32|36,36|42,42|48,51|53,53|58,66|86,86|91,91|93,93|96,96|102,107|118,119|126,131|139,143|146,146|150,152|154,154|163,163|167,168|180,181|199,204|207,208|210,211|216,226|229,235|237,238|243,261|266,266|270,270|286,316|335,336|339,339|341,347|362,362|364,366|370,370|372,373|378,379|384,385|392,392|407,408|423,423|425,425|428,432|435,437|444,445|447,447|453,453|455,455|458,458|461,463|467,469|476,478|484,487|492,492|494,497|501,502|510,510|523,524 Q:2,10|13,14|19,19|23,24|28,30|33,35|37,41|43,47|52,52|54,57|67,85|87,90|92,92|94,95|97,101|108,117|120,125|132,138|144,145|147,149|153,153|155,162|164,166|169,179|182,198|205,206|209,209|212,215|227,228|236,236|239,242|262,265|267,269|271,285|317,334|337,338|340,340|348,361|363,363|367,369|371,371|374,377|380,383|386,391|393,406|409,422|424,424|426,427|433,434|438,443|446,446|448,452|454,454|456,457|459,460|464,466|470,475|479,483|488,491|493,493|498,500|503,509|511,522 ??EEEEEEEEE??SS????E---EE???HHH--HSS?SSEEE-EEEEE?-??S?TTTT--------?HHHHHHHHHHHTTTTGGGG?EEEE?S-SS?EEEEE????--EEEEEEEESS?-GGGGTT??--??TTGGGGS?????TT?GGG---S?SEEEEEEE?TTS-?EEEEEEEETTT??HHHHHHHHHHHHHHTTT?---??SS??B??GGGG???--------SS???---?S??GGGS???????????????????EEEE-EEE?HHHHHHHHHGGGGGG???---------------------?----??HHHHHHHHHHHHHHHHTT??TT?E-------EEEEEEEEGGGTSS-S???TTB?S??EEEE??EEEH--HHHHHS?HHHHHHHHHHHHHT-?SHHHHHHHHHHHHH?S?SG-----GG???HHHHST--T?EEEEE?T-TS?SS???SSS???SEEEES???STTEE----EEEE?S----BSS??EEEEEEE?HHHHHHHHHHHT?? 2ZBA|A PF02461.11_AMO_seed 8 246 !Q:0,6|8,8|43,43|45,45|49,49|53,54|82,83|111,113|118,122|137,138|167,167|187,212|238,241|243,246 Q:7,7|9,42|44,44|46,48|50,52|55,81|84,110|114,117|123,136|139,166|168,186|213,237|242,242 ???????S?TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS?S?SSS?GGG??TTHHHHHHHHHHSHHHHHHHHHHHHHH??TTHHHHHHHHHHHHHHHHHHHIIIIIS???HHHH?????HHHHHHHHHHHHSS??HHHHHHHHHHHHHHHHHHHHHHHHGGGG?EEEETTEEEEHHHHHHHHS??????????????????????????HHHHHHHHHHHHHHHHHHHHHHHHT??-?B???- 3RFR|B PF02462.10_Opacity_seed 4 190 !Q:6,6|22,38|41,42|47,66|75,77|91,112|115,119|131,134|136,138|189,189 Q:0,5|7,21|39,40|43,46|67,74|78,90|113,114|120,130|135,135|139,188 EEEEET-TEEEEEEEEEEEESS??---------------SS??EEEE--------------------EEEEEEEE???SSSEEEEEEEEEE----------------------EE-----EEEEEETTEEE----E???EEEEEEEEEEEEEEETTEEEEEEEEEEEEEEETTEEEEEEEEEEEEEEEE? 1P4T|A PF02463.14_SMC_N_seed 29 1325 !Q:0,3|13,14|16,18|20,22|30,35|49,91|93,95|98,105|111,119|121,124|126,129|138,144|148,155|160,161|163,163|172,180|195,195|209,209|241,1134|1194,1195|1200,1201|1210,1210|1212,1213|1218,1218|1222,1222|1230,1230|1245,1249|1255,1256|1258,1258|1269,1269|1282,1283|1285,1285|1289,1289|1291,1291|1296,1296|1298,1298|1305,1309|1311,1311|1317,1322 Q:4,12|15,15|19,19|23,29|36,48|92,92|96,97|106,110|120,120|125,125|130,137|145,147|156,159|162,162|164,171|181,194|196,208|210,240|1135,1193|1196,1199|1202,1209|1211,1211|1214,1217|1219,1221|1223,1229|1231,1244|1250,1254|1257,1257|1259,1268|1270,1281|1284,1284|1286,1288|1290,1290|1292,1295|1297,1297|1299,1304|1310,1310|1312,1316|1323,1324 ????EEEESSSSB?-S???B???SSEEEEE??????TTHHHHHHHHHHT??-????????????????-------------???????????S???SE--------EEEEE?-------?B????B--??EEEEEESS??---??EEE--------TTEE??S-HHHHGGGT?????????EEEEHHHHHHHHHS?HHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT???????????-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?????????????-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------????????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS??EEEE??BSSSSGGG?B??EEEE?SSS?SEESSSS?TTHHHHHHHHHHHH-----HHHHS??S?EEEESTTTTS?THHHHHHHHHHH--H?SSS-S?EEEE?S?HHHHHH?----S?EEEEE??????BE 4I99|A PF02464.12_CinA_seed 102 175 !Q:12,12|17,18|51,51|61,63|71,71|86,86|92,97|103,103|107,108|112,115|119,119|133,139|144,144|148,149|151,152|156,157 Q:0,11|13,16|19,50|52,60|64,70|72,85|87,91|98,102|104,106|109,111|116,118|120,132|140,143|145,147|150,150|153,155|158,174 HHHHHHHHHHHH-HHHT??EEEEESTTTTHHHHHHTTSTTGGGTEEEEEEE?SHHHHHHHH???HHHHHHH?SSSHHHHHHHHHHH-HHTSS-----?SEEEE-EEE??SSS-???SSS?TTEEEEEEEETTS------?EEEE-EEE??S??HHH--HHHHHHHHHHHHHHHHH 2A9S|A PF02469.17_Fasciclin_seed 122 260 !Q:2,4|14,18|21,22|26,26|30,42|44,46|49,49|51,60|65,68|73,81|85,89|101,102|120,125|130,130|133,154|157,171|174,176|180,186|192,192|194,202|205,215|220,226|229,229|231,232|234,237|239,239|242,246|252,252|255,257 Q:0,1|5,13|19,20|23,25|27,29|43,43|47,48|50,50|61,64|69,72|82,84|90,100|103,119|126,129|131,132|155,156|172,173|177,179|187,191|193,193|203,204|216,219|227,228|230,230|233,233|238,238|240,241|247,251|253,254|258,259 SS---STTTTHHHH-----HT--TTH-HHH-------------T---SS-S---------?EEEE?-??HHHH---------TTS-----TTTHHHHTTSH--HHHHHHHHHHHHHEEES-??--?TTTS?SS----------------------EE---------------EE?--TTS?------EEEEE?T---------TS----------?EETT-------EE?S--B???-B?SS-----SEEEB?SS??-SS 1X3B|A PF02471.12_OspE_seed 8 117 !Q:0,1|10,10|12,16|28,28|39,48|57,57|76,76|80,82|90,90|92,92|96,96 Q:2,9|11,11|17,27|29,38|49,56|58,75|77,79|83,89|91,91|93,95|97,116 ??EEEEEEEE-E?????EEEEEEEEEEE?SSSEEEEEEE??????????EEEEEEEE?GGGHHHHHHHHHHSEEEE?SEE???TTBGGGT-T?EES?EEEEEEEEETTEEEEEEEEE 4J38|A PF02472.11_ExbD_seed 80 234 !Q:0,76|82,85|88,92|95,100|103,141|147,148|150,153|168,169|172,196|202,202|205,206|221,225|228,228|231,233 Q:77,81|86,87|93,94|101,102|142,146|149,149|154,167|170,171|197,201|203,204|207,220|226,227|229,230 ??-----------------------?----------------????-???????---------------????????EEEEE----TT-----TE------EE---------------------------------------ETTEE--E---?SSSHHHHHHHHSSS??SS------------------------?EEEEE?TT??HHHHHHHHHHHHHT-????EE?TT??? 2PFU|A PF02475.11_Met_10_seed 11 270 !Q:1,2|12,12|14,14|18,18|34,36|42,57|63,67|86,88|102,104|107,107|114,114|125,127|138,138|153,154|156,156|166,166|170,177|180,225|230,231|242,244|253,264 Q:0,0|3,11|13,13|15,17|19,33|37,41|58,62|68,85|89,101|105,106|108,113|115,124|128,137|139,152|155,155|157,165|167,169|178,179|226,229|232,241|245,252|265,269 S??EEETTEEEE?B?SSS?HHHHHHHHHTTTTSS-??SEEEE?????--?????????EEEEE-????EEEEEETTEEEEEETTTS???GGGHHHHHHHHTT-??TT?EEEETT?TTSHHHHTTT---TSSEEEEEES?HHHHHHHHHHHHHT--T?TTTEEEEES?GGG?----???EE----------------------------------------------EEEE??TTTGGGGHHH---HHHHEEEE------------EEEEE 3K6R|A PF02477.10_Nairo_nucleo_seed 3 444 !Q:0,7|25,25|27,27|33,33|36,37|39,42|52,53|73,75|98,100|118,120|140,141|149,150|153,154|156,160|182,198|210,211|217,217|224,224|243,246|271,271|305,307|321,322|339,342|353,353|365,376|378,378|382,383|398,398|401,401|408,411|419,421|425,426 Q:8,24|26,26|28,32|34,35|38,38|43,51|54,72|76,97|101,117|121,139|142,148|151,152|155,155|161,181|199,209|212,216|218,223|225,242|247,270|272,304|308,320|323,338|343,352|354,364|377,377|379,381|384,397|399,400|402,407|412,418|422,424|427,443 ????????SHHHHHHHHHHHHHTTT?B?SSBSS?BS??S????HHHHHHHHT??SSSTTHHHHHHHHHHHHTT???HHHHHHHHSHHHHHHHHHTGGG?--HHHHHHHHTTHHHHTTS???HHHHHHHHHHHHHHHHHHT??SSSTTSB??SB??S?????TTTHHHHHHHHHHHHHHHHTT?????????-???????HHHHHHHHHHT??GGGGS?SSSSTT?BSSSSBHHHHHHHHHTTT????THHHHHHHHHHHHHHHHHHTGGGS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT???HHHHHHHHHHHHT??GGGHHHHHHHHHHHTT????HHHHHHHHHH?SSTHHHHHHHT????????????S?TTS??STTHHHHHHHHSSS?TT?GGGGGG????GGGGGGB???SSS??HHHHHHHHHHHHHHHHS 4AQF|A PF02480.11_Herpes_gE_seed 19 595 !Q:0,228|235,236|241,242|245,246|249,251|258,258|261,263|274,277|280,280|282,282|292,292|301,301|304,304|310,314|317,317|327,327|331,334|339,339|346,348|354,357|360,360|368,369|373,373|378,387|406,406|410,413|418,595 Q:229,234|237,240|243,244|247,248|252,257|259,260|264,273|278,279|281,281|283,291|293,300|302,303|305,309|315,316|318,326|328,330|335,338|340,345|349,353|358,359|361,367|370,372|374,377|388,405|407,409|414,417 ???????????-----------------?????????------------------???????---???----??????-------??????????????????----????????????-----?????????????????????---??????????--???????????????????????????????????????????????????????-???????--????EEEEEE??SEEE??TT??EE???EEEEEE?SS-??EEEEEEEEEE??-?TT?S?EEEEHHHHH?TTSHHHHS?TT-GGGEE??--?SS?SEEEEEEEE?SSS---?TTTT-EEEEEE???TTEEE?---SS?SSEEESS??GGG?EEEE----------EEEEETTEEEEEEEEEEE?TTT-???EEEE??????----------------?????????????????????????--------------------------------?------------------------------------?------------------------------------------------------------- 2GJ7|E PF02481.10_DNA_processg_A_seed 97 300 !Q:1,1|6,9|11,11|16,18|23,23|29,29|31,40|42,46|48,53|61,71|76,79|82,83|90,90|93,94|109,109|111,111|113,118|120,121|126,128|141,145|149,158|163,163|166,166|168,169|171,176|189,189|191,192|201,205|207,207|210,214|229,229|237,238|241,241|255,259|264,272|285,288|293,294|297,297 Q:0,0|2,5|10,10|12,15|19,22|24,28|30,30|41,41|47,47|54,60|72,75|80,81|84,89|91,92|95,108|110,110|112,112|119,119|122,125|129,140|146,148|159,162|164,165|167,167|170,170|177,188|190,190|193,200|206,206|208,209|215,228|230,236|239,240|242,254|260,263|273,284|289,292|295,296|298,299 H-HHSS?---E-EETT---STTS?HHHHT-S----------T-----T---??-SEEEEEE----------?GGGG----GS-?EEEEEE?TT??HHHHHHHHHHHHTT-T-T-----?S--EEEE???TTHHHHHHHHHH-----HHT--------??EEEE?SS?T--T??----SSGGGHHHHHHH-H--HHSEEEES-----S?TT??-??TTHHHHHHHHHHHH?SEEEEES??TT?HHHHHHHHHHHTT----?EEEE-?----???SSSSTTHHHHHH----HHTT-?EE?SS 3MAJ|A PF02482.14_Ribosomal_S30AE_seed 144 131 !Q:6,7|10,10|12,14|28,28|31,31|34,41|43,45|48,48|51,52|59,67|70,72|81,81|84,85|89,90|97,97|124,130 Q:0,5|8,9|11,11|15,27|29,30|32,33|42,42|46,47|49,50|53,58|68,69|73,80|82,83|86,88|91,96|98,123 EEEEEE--ES-S???HHHHHHHHHHHHH-HT-TT?-?----?E---EE-EE--EEEEEE---------TT---EEEEEEEE-EE--TTE--EEEEEE-EESSHHHHHHHHHHHHHHHHHHHHHH--??-?? 1L4S|A PF02485.16_Branch_seed 47 342 !Q:7,7|9,10|22,27|31,32|39,39|43,43|54,59|63,63|69,69|72,76|97,97|99,102|116,116|130,131|133,133|135,135|139,140|145,146|156,156|162,163|169,179|181,181|184,185|188,189|191,191|203,204|206,207|209,209|221,255|277,279|285,285|287,287|294,300|303,304|309,309|311,311|316,316|319,321|332,333 Q:0,6|8,8|11,21|28,30|33,38|40,42|44,53|60,62|64,68|70,71|77,96|98,98|103,115|117,129|132,132|134,134|136,138|141,144|147,155|157,161|164,168|180,180|182,183|186,187|190,190|192,202|205,205|208,208|210,220|256,276|280,284|286,286|288,293|301,302|305,308|310,310|312,315|317,318|322,331|334,341 EEEEEEE?S-?HHHHHHHHHHH?----?TTS--EEEEEE?TTS?HHHHHHHHHH------HHT?TTEEE?SS?????TTSHHHHHHHHHHHHHHHHH?S-???EEEEEETTEEESS?HHHHHHHHHHHTT??E-E?BEE??GGGT--HHHHEEEEE?SSSEE--EEEEE????-------S?SS??EE??S?EEEEHHHHHHH--H--H?HHHHHHHHHHT-----------------------------------TSSSGGGTHHHHHTTSTTSTT???SSGGG?B?TTTSSS-------EE??BGGG?S?GGGT?SS???SSEEETTEEE??GGGHHHHT 2GAM|A PF02489.11_Herpes_glycop_H_seed 30 791 !Q:0,0|3,4|16,17|29,31|33,36|38,38|41,49|51,54|57,59|61,61|64,68|71,74|78,79|81,81|85,91|100,101|103,105|108,108|110,110|112,112|119,123|125,125|133,135|147,147|157,158|160,160|162,162|166,166|180,182|184,184|187,188|191,191|198,198|208,208|212,212|217,217|221,224|236,236|242,242|253,253|261,261|263,265|267,267|321,321|323,341|345,347|349,357|359,360|373,373|378,380|384,384|399,400|405,406|429,436|438,439|441,441|458,470|476,477|494,494|501,508|518,526|534,537|546,548|550,565|568,568|588,588|599,599|602,602|606,608|615,616|619,619|624,624|630,630|633,634|637,638|641,641|644,645|649,650|656,656|658,658|661,663|666,669|672,672|675,676|679,680|682,683|686,686|689,690|695,696|713,714|725,726|729,732|734,734|739,743|748,748|752,752|757,790 Q:1,2|5,15|18,28|32,32|37,37|39,40|50,50|55,56|60,60|62,63|69,70|75,77|80,80|82,84|92,99|102,102|106,107|109,109|111,111|113,118|124,124|126,132|136,146|148,156|159,159|161,161|163,165|167,179|183,183|185,186|189,190|192,197|199,207|209,211|213,216|218,220|225,235|237,241|243,252|254,260|262,262|266,266|268,320|322,322|342,344|348,348|358,358|361,372|374,377|381,383|385,398|401,404|407,428|437,437|440,440|442,457|471,475|478,493|495,500|509,517|527,533|538,545|549,549|566,567|569,587|589,598|600,601|603,605|609,614|617,618|620,623|625,629|631,632|635,636|639,640|642,643|646,648|651,655|657,657|659,660|664,665|670,671|673,674|677,678|681,681|684,685|687,688|691,694|697,712|715,724|727,728|733,733|735,738|744,747|749,751|753,756 ?SS??HHHHHHHTTTT??HHHHTHHHHTS???S----S?EE????-????S????TT???B?SS??--?SS????SSS??E-EEH-------HHHHHHHT??B?-?SS?S?H-HHHHHB?????B?BEEEEEE---TTTTEEEEEEE?SSEEEEEEE--E-E?SSS?EEEEEEEEEEGGG???B?SS??GG-GGEEEE?SSEEEEEEE?HHH-HHHH-HTT????HHHHHHHTTSS?HHHHH-HHHHHHHHHH-HHTTTTT-S???S-HHHHHHHHHHHHHHHHHHHHHHHSTTSEEEHHHHHHHHHHHHHHHHHHHHHSS?E-------------------EES???H---------H--HHHHHHHHHHTS?GGGG---GGS?HHHHHHHHHHHHHH--TTTS?-SSSSHHHHHHHHHHHHHHTSSS???-----T--T?HHHHHHHHHHHHHHHH-------------HHSSS??SHHHHHHHHHHHHHHS?HHHHHH--------HHHHHHHTS????---??GGGGSSB????HHHHHHHS???T----------------TS?HHHHHHHHHHHHHHHHHHS?TTTTSSSGGG-GG?SSG---GGEEEE--EE?SSEE-EEEES?TT??SS??EE?SB??SSS??EEEEE-E-TT???SS-???SS?EE??EE??S?-SS?SS?-TTSS-?EEEEEESSSSEEEEEE??SHHHHHHHHT--TT????S?TTEE-----EEEE?SSS?EEEE??-------------------------------- 2XQY|A PF02491.15_SHS2_FTSA_seed 50 87 !Q:1,1|12,12|14,16|19,19|22,23|42,44|59,59|66,66|68,69|72,72 Q:0,0|2,11|13,13|17,18|20,21|24,41|45,58|60,65|67,67|70,71|73,86 T?EEEEEEEEEE?T---TS?EE??HHHHHHHHHHHHHHHHHT---TEEEEEEEEEEEEE-TTTEEE-S??TT?EESEEEEEEEEEEE 4A2B|A PF02492.14_cobW_seed 62 288 !Q:6,7|23,23|28,30|32,32|38,40|42,43|52,61|65,66|69,70|72,81|87,89|92,92|100,101|113,138|141,150|153,154|160,160|162,164|167,192|196,196|202,205|210,234|237,237|244,245|251,251|258,258|267,268|284,284 Q:0,5|8,22|24,27|31,31|33,37|41,41|44,51|62,64|67,68|71,71|82,86|90,91|93,99|102,112|139,140|151,152|155,159|161,161|165,166|193,195|197,201|206,209|235,236|238,243|246,250|252,257|259,266|269,283|285,287 EEEEEE??TTSSHHHHHHHHHHH-HTTT---S?EEEEE???S--SHHHHHHH----------HHH--HT??G----------GGEEE???TT?HHHHHTT??HHHHHHHHHHH--------------------------HH---------?TT??EEEEE?S???TT????----------------------TTT?SEEEE----EEET-------------------------TT?SSHHHH??HHHHT?SEEEEE?GGGHHHHT??HHHHHHHHHHHHTTS?EEE 1JPN|A PF02493.15_MORN_seed 271 24 !Q:5,5|18,18|22,22 Q:0,4|6,17|19,21|23,23 EEEEE-ETTEEEEEEEEE?TTS?E 1MUF|A PF02499.10_DNA_pack_C_seed 27 377 !Q:0,108|110,110|120,123|127,127|131,132|134,134|143,146|152,152|163,165|179,180|183,183|185,185|208,209|218,218|221,221|238,251|256,257|259,260|262,263|265,268|271,271|273,274|293,293|302,302|310,310|322,350|365,365|367,376 Q:109,109|111,119|124,126|128,130|133,133|135,142|147,151|153,162|166,178|181,182|184,184|186,207|210,217|219,220|222,237|252,255|258,258|261,261|264,264|269,270|272,272|275,292|294,301|303,309|311,321|351,364|366,366 -----------??-------------------------------???????????----------??--------------------------?----????-??????S?HHHHHHHHH????STT?GGG--B?SEEEEEEE????SSSTT?EEEEEEEEEE---TTEEEEEEEEEEE??TT?S?HHHHHHHHHHHHHHHHHHHSTT??SEEEEEEB?SS?HHHHHHHHHHHHHHHT??????????????EEEE??B??T--T????BS?B??STTHHHHHHHHHHHHHTT?EEEEEEEE?SSSSSSS?HHHHHHHHHTT?????????---????????--?-?????HHHHHHHHHHHHHT-S?????????? 2KN8|A PF02501.12_T2SI_seed 100 104 !Q:0,0|21,34|51,51|53,55|58,69|77,85|89,89|92,93|101,103 Q:1,20|35,50|52,52|56,57|70,76|86,88|90,91|94,100 ?HHHHHHHHHHHHHHHHHHHT?---?????---??EEEEEETTEEEEEEEE-E???SS?-?-------??EEEEEEE---------SSS-SS??SEEEEEE??? 3CFI|A PF02502.13_LacAB_rpiB_seed 170 198 !Q:2,2|7,7|25,27|29,32|37,40|43,43|45,50|64,69|72,72|74,77|80,89|91,91|112,113|117,117|131,132|138,145|151,151|162,168|172,180|186,187|193,196 Q:0,1|3,6|8,24|28,28|33,36|41,42|44,44|51,63|70,71|73,73|78,79|90,90|92,111|114,116|118,130|133,137|146,150|152,161|169,171|181,185|188,192|197,197 EE-EEEE?GGGHHHHHHHHHHHHHT---T--?-EEEE????SS-S---???HHHHHHHHHHHHH------TT-S----SS----------E-EEEEESSSHHHHHHHTTSTT??EEE?SSHHHHHHHHHTT??SEEEE--------ETTTS?HHHHHHHHHH-------HHH????----?THHHH--HHHHH----H 4EM8|A PF02503.12_PP_kinase_seed 173 345 !Q:18,20|23,24|27,28|34,34|37,37|46,46|48,61|63,68|70,119|121,128|131,132|134,134|139,142|147,147|151,152|154,164|170,171|173,186|206,208|221,223|225,225|228,231|234,234|236,236|243,244|249,249|254,258|264,264|267,269|279,288|292,293|295,295|302,304|306,308|315,319|321,324|329,335|337,341|345,345 Q:0,17|21,22|25,26|29,33|35,36|38,45|47,47|62,62|69,69|120,120|129,130|133,133|135,138|143,146|148,150|153,153|165,169|172,172|187,205|209,220|224,224|226,227|232,233|235,235|237,242|245,248|250,253|259,263|265,266|270,278|289,291|294,294|296,301|305,305|309,314|320,320|325,328|336,336|342,344 TTHHHHHHHHHHHHTGGG???EE??TT??TTTTS?TT?EEEEEEEE-E--------------T------T--------------------------------------------------E--------EE--E-EEEE??--TTTS?SEE--E??--------?SSSTT??E--------------EEEHHHHHHHHHHHHHTTT???SEEEEEEEEEEE???S?TT----TT-S?SSSTTS??TTSS-TTTS?--??EEEEE?TT-??HHHHHHHHH----------HTT??S-SSEEEE-??S???GGGGGG???-?S---?GGGS??-????B-??--GGG- 1XDP|A PF02504.10_FA_synthesis_seed 11 351 !Q:8,8|15,17|30,30|40,40|48,49|51,57|60,60|66,67|69,71|75,75|83,83|100,100|106,106|108,108|121,121|123,123|126,126|129,129|133,133|136,137|140,140|142,143|148,148|152,152|155,156|176,178|181,182|195,195|197,197|199,203|215,215|217,219|237,237|242,243|245,250|279,291|303,303|308,309|315,315|319,319|323,324|327,328 Q:0,7|9,14|18,29|31,39|41,47|50,50|58,59|61,65|68,68|72,74|76,82|84,99|101,105|107,107|109,120|122,122|124,125|127,128|130,132|134,135|138,139|141,141|144,147|149,151|153,154|157,175|179,180|183,194|196,196|198,198|204,214|216,216|220,236|238,241|244,244|251,278|292,302|304,307|310,314|316,318|320,322|325,326|329,350 EEEEEESS?SSSTTH---HHHHHHHHHHHH?TTEEEEEEE?HHHHHTT??S-----??TT-EEEEE??B???TTS?HHHHHHH?TTBHHHHHHHHHHTTS?SEEEE?S?HHHHHHHHHHTT?B?TT?SS?EEE?EE??SS-S??EEEE?SSS?SS??HHHHHHHHHHHHHHHHHTS-??SS?-EEEEEESSSSTT?S?H-----HHHHHHHHHHS?T---TSEEEEEEEGGGGGGTS?SEEE??H------HHHHHHHHHHHHHHHHHHHHHHHHHTTT?????????---?HHHHHHHHHHH?GGGS??EEEET-BSS?EEE??TT??HHHHHHHHHHHHHHHHTTHHHH 1U7N|A PF02507.10_PSI_PsaF_seed 10 184 !Q:0,26|29,31|35,35|50,52|54,55|57,57|60,60|63,64|76,77|79,79|81,88|91,94|96,97|100,103|107,108|136,136|138,138|141,143|150,150|165,165|179,179|183,183 Q:27,28|32,34|36,49|53,53|56,56|58,59|61,62|65,75|78,78|80,80|89,90|95,95|98,99|104,106|109,135|137,137|139,140|144,149|151,164|166,178|180,182 ???????????????????????????SS???SSS?HHHHHHHHTTGGGS???S??S?SS?SS??STTTTSHHHHS??S?S????????SS????B??SS----SSS??TTTSHHHHHHHHHTTTTTTTTTTTTTT?S?SS?-?SSTTTS?SSSTTTTSGGGGTT?SSTHHHHTTSSSS?GGG? 2WSE|F PF02509.9_Rota_NS35_seed 3 317 !Q:0,1|12,12|21,22|32,35|42,42|45,45|49,49|52,53|61,61|70,70|91,91|93,93|97,97|104,104|106,107|120,120|128,128|142,143|146,148|152,155|161,161|170,170|174,174|178,179|181,181|184,185|196,198|213,213|221,221|249,261|266,266|280,281|292,298|313,316 Q:2,11|13,20|23,31|36,41|43,44|46,48|50,51|54,60|62,69|71,90|92,92|94,96|98,103|105,105|108,119|121,127|129,141|144,145|149,151|156,160|162,169|171,173|175,177|180,180|182,183|186,195|199,212|214,220|222,248|262,265|267,279|282,291|299,312 ??BGGGTEEEEE?SSSEEEEE??HHHHHHHHT????TTSSSS?EE?SSS?EE??GGGGGGB?BTTBSSSB?TTSHHHHHHHHHHHHHHHTT?B?TTT-HHHHHT?B??HHHHHHHHHHHT?TTSGGGT?HHHHHHHHHHHTT??SS???GGG????EEEEE?SSEEEEEE?TTS?SSS??S?TT??EEEEEESSSS???HHHHHHHHHHHHHH?TTEEEEE?SSSSEEEEEGGGHHHHHHHHHHHHHTT?????????????TTTS?HHHHHHHHHHHTT??HHHHHHTTSS???????TTTTHHHHHHHHHH???? 2R7C|A PF02511.10_Thy1_seed 163 483 !Q:5,9|17,35|37,51|65,81|83,130|138,138|144,145|148,154|160,160|162,165|172,172|184,185|187,187|191,191|194,195|200,258|260,272|274,278|285,303|306,306|313,315|326,359|367,367|370,395|397,404|406,409|418,418|437,437|445,452|456,456|458,458|470,470|475,477|479,479 Q:0,4|10,16|36,36|52,64|82,82|131,137|139,143|146,147|155,159|161,161|166,171|173,183|186,186|188,190|192,193|196,199|259,259|273,273|279,284|304,305|307,312|316,325|360,366|368,369|396,396|405,405|410,417|419,436|438,444|453,455|457,457|459,469|471,474|478,478|480,482 ETTTE-----EEEEEEE-------------------E---------?----?HHHHHHHHHGGGT?-----------???-?H------------------------------------------------HHHHHHH-HHHHH--HT?-----?GGGGG?E----EEEEEE-EEHHHHHHHTT??S-SEE-EE??TTTS-------------------------------------------------------?-??S---?---------B??-??GGGGTT???----------------SS?HHHHHH---HHHHHHHHHH----------------------------------HHHHHHH-HT--------------------------T------??H----HHHGGGSB-TTBEEEEEEEEEHHHHHH-HHHHHSS--------TTS?H-HHHHHHHHHHH-HHHH---H?HHH 3N0C|A PF02513.12_Spin-Ssty_seed 27 51 !Q:2,2|9,10|12,12|14,16|27,27|30,30|33,33|41,41|44,44|48,48 Q:0,1|3,8|11,11|13,13|17,26|28,29|31,32|34,40|42,43|45,47|49,50 TT?EEEEEE??T-T???EEEEEEEEEE?TT?TT?EEEEETT?SB?EEE?TT 2NS2|A PF02515.12_CoA_transf_3_seed 118 292 !Q:2,3|19,22|24,24|30,32|41,41|44,46|51,54|57,62|65,65|74,75|77,80|83,84|89,90|92,94|97,97|106,110|114,114|116,119|121,125|129,138|141,143|150,150|157,159|167,170|174,175|177,177|179,183|186,189|198,198|203,204|215,215|217,217|219,231|235,246|253,254|260,263|267,273|278,279|281,283 Q:0,1|4,18|23,23|25,29|33,40|42,43|47,50|55,56|63,64|66,73|76,76|81,82|85,88|91,91|95,96|98,105|111,113|115,115|120,120|126,128|139,140|144,149|151,156|160,166|171,173|176,176|178,178|184,185|190,197|199,202|205,214|216,216|218,218|232,234|247,252|255,259|264,266|274,277|280,280|284,291 EE??TTSHHHHHHHHHHHH----T?SEEEE???TTTTGGGT?SH---HHHH----HH?-----TT?EEEEEESS?-S----SS--TTTT--S???HH-HHHHHHST-----TTT-S----S?----TTS-?---?-???SS?--HHHHHH-HHHHHH---HHHHHHH----HHH--H-H??--?EE----EEEEHHHH-HHHT-?HHHHHHHHHH-S-S???---??-----TTS?-----------SSSSSE--EEEEE----TTE-------EEEE--E-??SHHHHHHH 1XVV|A PF02516.9_STT3_seed 15 657 !Q:18,26|33,35|37,39|56,65|68,70|81,81|84,85|87,87|94,94|104,105|107,112|139,139|145,145|159,160|171,175|201,202|229,229|232,240|262,271|273,275|281,295|306,307|316,316|318,325|329,330|334,335|349,360|370,374|380,380|387,390|407,424|432,444|457,459|461,462|465,467|472,472|474,474|477,477|481,486|505,522|534,535|555,556|573,577|582,594|601,601|608,616|621,626|646,649 Q:0,17|27,32|36,36|40,55|66,67|71,80|82,83|86,86|88,93|95,103|106,106|113,138|140,144|146,158|161,170|176,200|203,228|230,231|241,261|272,272|276,280|296,305|308,315|317,317|326,328|331,333|336,348|361,369|375,379|381,386|391,406|425,431|445,456|460,460|463,464|468,471|473,473|475,476|478,480|487,504|523,533|536,554|557,572|578,581|595,600|602,607|617,620|627,645|650,656 HHHHHHHHHHHTTTTHHH---------HBSSSB???S---SHHHHHHHHHHHHHHT----------TT???SEETTSSTTT?EE??S?HHHHHH-HHHHHHHTT??S------HHHHHHHHTHHHHHHHHHTHHHHHHH-HHHHS?HHHHHHHHHHTTT??THHHHTTSTT??--?SHHHHHHHHHHHHHHHHHHHHHHTT??TTSSSTGGGGHHHHHHHHHHHHHHTT?GG---------GGGHHHHHHHHHHHHHHTTTT----------S???HHHHH---------------HHHHHHHHHH--HHHHGGGS?S--------SSS??SSS??HHHHHHHHHHHHH------------HHHHHHHHH-----HHHTT-HHHHTT?---GGGHHHHHHHHHHHSS------------------TTGGGTS?------------TTHHHHHHHHHS???S??SS???SSSS?T-TS?SSS??---?SHHHHHHHTTHHHHHHHH------------------HHHHHHHHHHS??HHHHHHHHHHHHHHHHHHH?-GGGGGGTHHHHHHHHH-----HHHH-------------HHHHHT?TTTTHH---------HHTT??????HHHHHHHHHHHHHHHHHHH----HHHHHHS 3VU0|A PF02518.21_HATPase_c_seed 659 327 !Q:1,1|20,21|24,41|53,115|123,125|127,148|151,156|158,186|197,234|242,242|247,250|253,262|270,307|313,313|317,321 Q:0,0|2,19|22,23|42,52|116,122|126,126|149,150|157,157|187,196|235,241|243,246|251,252|263,269|308,312|314,316|322,326 S?HHHHHHHHHHHHHHHHHT??TT----------------??EEEEEEEETTT---------------------------------------------------------------TEEEEEE---E?------------------?--SS---???T-----------------------------TTTTTTTSTT?????--------------------????????--???HHHHHHH-HHHH----TT-??-------EEEEEET--------------------------------------TTEEE-EEE-----EEEEE 1UYH|A PF02522.9_Antibiotic_NAT_seed 52 274 !Q:4,4|9,9|17,22|33,33|36,36|42,44|49,49|52,54|56,57|60,62|73,77|81,85|89,89|101,101|104,104|106,106|110,110|122,122|126,127|143,144|148,148|155,156|160,160|170,172|175,176|182,185|190,191|205,217|220,225|240,242|252,252|268,268 Q:0,3|5,8|10,16|23,32|34,35|37,41|45,48|50,51|55,55|58,59|63,72|78,80|86,88|90,100|102,103|105,105|107,109|111,121|123,125|128,142|145,147|149,154|157,159|161,169|173,174|177,181|186,189|192,204|218,219|226,239|243,251|253,267|269,273 EEEE?STTS?EETTHHH------HHHHHHHHHH?TT?EEEEE???TTSS?GG---G??SS???GGGHHHHHHH?????TTT?-??-SSS?HHHHHHTTSTT?EE?S?TTT?EEEEETTHHHH-HTT??STTTTSTTSHHHHHH--HTT?EEEEES??GGG?TTHHHHHHH???TT??EEEEE----EEEE--ETTEEEEEEEEEE????---------TT------HHHHHHHHHHHSTT--?EEEEETTEE-EEEEEHHHHHHHHHH-HHHHH 3SLB|A PF02525.12_Flavodoxin_2_seed 247 320 !Q:0,1|8,9|11,19|24,31|48,48|51,54|56,59|63,63|70,78|80,80|87,131|135,137|143,146|158,158|165,166|173,173|184,185|189,193|198,201|206,208|210,211|214,220|222,223|231,232|235,237|239,247|250,250|253,254|259,259|265,265|270,272|274,277|282,284|286,287|290,294|296,296|310,313 Q:2,7|10,10|20,23|32,47|49,50|55,55|60,62|64,69|79,79|81,86|132,134|138,142|147,157|159,164|167,172|174,183|186,188|194,197|202,205|209,209|212,213|221,221|224,230|233,234|238,238|248,249|251,252|255,258|260,264|266,269|273,273|278,281|285,285|288,289|295,295|297,309|314,319 ?-EEEEEE??S---------SGGG-------?HHHHHHHHHHHHHHHH?TT--?-E----EEE-EETTTS-?--?????H-HHHHHH??---------------------------------???----???HHH---HHHHH----HHHHHHHHHHH?SEEEEE??EETTEE?HHHHHHHHHH??BTT-----TEEE----ETTE---E--EE??----?S?-EEEEEEE?-SS?-?T---------TS-TT??HHHH-HHHHH-HHTT???E----EEEE---E??TT-----S?HHHHHHHHHHHHH----HHHHHH 3U7R|A PF02527.10_GidB_seed 17 204 !Q:15,30|46,47|51,57|63,63|76,76|81,84|91,91|107,107|115,116|120,123|125,127|129,129|135,135|137,137|151,151|166,167|175,175|188,198 Q:0,14|31,45|48,50|58,62|64,75|77,80|85,90|92,106|108,114|117,119|124,124|128,128|130,134|136,136|138,150|152,165|168,174|176,187|199,203 HHHHHHHHHHHHHHH??????????--????HHHHHHHHHHHHGGG??SSE-------EEEET?TTTTTHHHHHHH?TTSE----EEEEES?HHHHHHHHHHHHHTT?SSEEEEE??TTT----S???S?EEEEE?S?SSSHHHHHHHHTT-SEEEEEEEEEEESS??HHHHHTS?TTEEEEEEEEEE????-??----EEEEE 3G8B|A PF02529.10_PetG_seed 17 38 !Q:0,2|29,37 Q:3,28 ???HHHHHHHHHHHHHHHHHHHHHHHHHH????-???? 2ZT9|G PF02531.11_PsaD_seed 20 145 !Q:0,2|5,8|10,14|18,19|26,28|32,34|37,41|46,52|55,55|59,59|71,71|77,80|82,84|88,92|95,96|98,99|106,106|110,111|113,115|117,120|124,124|131,133|135,137|140,140|143,145 Q:3,4|9,9|15,17|20,25|29,31|35,36|42,45|53,54|56,58|60,70|72,76|81,81|85,87|93,94|97,97|100,105|107,109|112,112|116,116|121,123|125,130|134,134|138,139|141,142 ???SS????S?????SSS??STTTSS???EEE???SS?????TTTT???????SS?EEE?SSTTTTSHHHH-TTTSS?--?S-??EEE??--?SS??S??TTTSSS?SSS??S???S????SSS?STTTTS???S???TT-SS??- 2WSE|D PF02532.9_PsbI_seed 15 38 !Q:0,0|32,33|35,37 Q:1,31|34,34 ?HHHHHHHHHHHHHHHHHHHHHHHTTTTTSSS--S??? 3PRR|I PF02533.10_PsbK_seed 25 44 !Q:0,9|42,43 Q:10,41 ??????--??TTGGGGHHHHTTGGGHHHHHHHHHHHHHHHTT?? 3PRR|K PF02534.9_T4SS-DNA_transf_seed 9 608 !Q:0,0|3,3|11,11|13,14|17,19|23,25|29,53|58,67|70,70|75,76|95,96|110,116|119,120|123,123|127,127|133,139|144,145|150,151|161,161|163,163|169,197|218,219|221,224|226,228|240,240|255,257|261,261|288,307|311,317|321,321|324,326|330,333|335,335|340,356|369,369|379,381|384,392|399,399|404,404|406,406|416,416|429,429|436,439|442,442|453,454|459,462|464,466|478,478|485,513|515,515|522,523|528,539|543,543|547,548|550,550|555,592|594,594|596,605|607,607 Q:1,2|4,10|12,12|15,16|20,22|26,28|54,57|68,69|71,74|77,94|97,109|117,118|121,122|124,126|128,132|140,143|146,149|152,160|162,162|164,168|198,217|220,220|225,225|229,239|241,254|258,260|262,287|308,310|318,320|322,323|327,329|334,334|336,339|357,368|370,378|382,383|393,398|400,403|405,405|407,415|417,428|430,435|440,441|443,452|455,458|463,463|467,477|479,484|514,514|516,521|524,527|540,542|544,546|549,549|551,554|593,593|595,595|606,606 ?EE?HHHHHHH-H??SS???EET---TEE------??-----------------GGGG----------GG?EEEE??TTSSHHHHHHHHHHHHTT?-EEEEEEETTHHHH-------HH??SS?EEE?TTBTT??--???GGGG??STTH--HHHHHHHHS?B?SSHHH-----------------------------HHHHHHHHHHHHHHHHHHHH--T----T???HHHHHHHHHTS?HHHHHHHHTTSTHH---HHT?SSHHHHHHHHHHHHHHHHHTHHHHTS??--------------????HHH-------HHH?TT???EEE----E?GGGH-----------------HHHHHHHHHHHH-HHHHHGGGS???TT?-------?EEEEES?GGGS?B?SSHHHHHHH?TTTTEEEEEEES?HHHHHH----HH?HHHHHHHHHT??EEEE????T?--HHHHHHHHHHH?EEEEEE?????-------???????-----?????S?HHHHHT??TTEE------------EEE?SSS??E-EEEE?--??---------------------------??????S?S??--------B? 1GKI|A PF02536.9_mTERF_seed 15 378 !Q:0,0|12,12|17,22|25,25|27,27|33,33|36,37|49,51|62,62|69,70|86,87|98,98|105,107|123,124|135,135|142,142|162,162|164,164|176,176|183,183|199,201|219,220|222,252|269,278|281,282|293,293|300,300|304,305|318,319|333,333|349,350|353,355|358,358|365,365 Q:1,11|13,16|23,24|26,26|28,32|34,35|38,48|52,61|63,68|71,85|88,97|99,104|108,122|125,134|136,141|143,161|163,163|165,175|177,182|184,198|202,218|221,221|253,268|279,280|283,292|294,299|301,303|306,317|320,332|334,348|351,352|356,357|359,364|366,377 ?HHHHHHHHTTS?HHHH------HH-H?HHHHT?SS??HHHHHHHHHHT???HHHHHHHHHH?GGGGGS?-HHHHHHHHHHHHHHH??HHHHHHHHTT?SHHHHS???HHHHHHHHHHHHTTT??HHHHHHHHHH?THHHHS?HHHHHHHHHHHHHHHHHTT?S?HHHHHHHHHHH?GGGTTS?HHHHHHHHHHHHHHH???HHHHHHHHHTTTSGGGT??T-------------------------------THHHHHHHHHHHHHHT----------TT??HHHHHHHHHT?GGGGGS?HHH--HHHHHHHHHHTT??HHHHHTSGGGGGS?HHHHHHHHHHHHHTT??TT---TS?GGGGGS?HHHHHHHHHHHH 3M66|A PF02540.12_NAD_synthase_seed 11 273 !Q:12,16|18,18|20,20|25,26|43,52|61,65|68,68|84,84|89,91|101,104|107,107|109,115|140,140|144,147|155,155|157,157|163,163|167,167|173,173|186,192|199,203|205,207|211,212|220,220|230,232|238,240|250,251|271,272 Q:0,11|17,17|19,19|21,24|27,42|53,60|66,67|69,83|85,88|92,100|105,106|108,108|116,139|141,143|148,154|156,156|158,162|164,166|168,172|174,185|193,198|204,204|208,210|213,219|221,229|233,237|241,249|252,270 HHHHHHHHHHHH----?T-T?EEEE??SSHHHHHHHHHHHHHH---------?GGGEEEEE??---SS?STHHHHHHHHHHHHT?EEEE???HHHHHHHHH----HH?S??----?HHHHHHHHHHHHHHHHHHHHHHHT?EEE????HHHHHHT?S?TTSTT?SSB?TTTTS?HHHHHHHHHHHT-----??HHHHHS?????S---STT??HHHHHTS?HHHHHHHHH---HHHTS???HHHHHHTTT??HHHHHHHHHHHHTTGGGSS?? 1WXG|A PF02541.11_Ppx-GppA_seed 10 326 !Q:9,12|22,24|29,29|31,31|34,39|41,41|62,63|65,66|74,74|80,80|94,94|96,100|102,102|106,107|124,127|129,129|136,136|139,139|148,152|163,164|177,178|180,181|196,197|209,214|236,236|238,244|247,247|249,249|263,263|266,269|273,275|278,279|302,302|304,305|309,309|311,312 Q:0,8|13,21|25,28|30,30|32,33|40,40|42,61|64,64|67,73|75,79|81,93|95,95|101,101|103,105|108,123|128,128|130,135|137,138|140,147|153,162|165,176|179,179|182,195|198,208|215,235|237,237|245,246|248,248|250,262|264,265|270,272|276,277|280,301|303,303|306,308|310,310|313,325 EEEEEETTE----EEEEEEEEE???TGGG-B?TT?----?B?HHHHHHHHHHHHHHHHHTTT??G--GGEEEEE?HHHHH?TTHHHHHHHHTTT?S-----S?EEE??HHHHHHHHHHHHHHHS-???S?EEEEEE?SS?EEEEEEET-----TEEEEEEEES??HHHHHHHHSGGG--B??HHHHHHHHHHHHHH--HTTTHHHHHHH?----?SEEEEESHHHHHHHHHHHHTT?S-------SS?B?HHHHHHHHHHHTT?SB----GGG???TT??TTGGGTHHHHHHHHHHHHHHHT?S-?BEE?S??HHHHHHHHHHHHH 1U6Z|A PF02542.11_YgbB_seed 167 221 !Q:12,35|37,48|50,50|55,56|58,59|61,71|73,73|79,80|83,86|101,103|105,107|113,113|116,116|120,124|127,129|146,147|157,157|159,159|163,164|168,168|183,183|193,194|197,197|213,214|218,220 Q:0,11|36,36|49,49|51,54|57,57|60,60|72,72|74,78|81,82|87,100|104,104|108,112|114,115|117,119|125,126|130,145|148,156|158,158|160,162|165,167|169,182|184,192|195,196|198,212|215,217 EEEEEEEEEEES------------------------S??------??-?B?SSSB??S--S-----------T-THHHH--TT--??HHHHHHHHHHHHHT---T???HHHHS?HH-HHS-----SS???HHHHHHHHHHHHHTTT?-EEEEEEEEE-E?SSS??TTT-HHHHHHHHHHHTTS?GGGEEEEEE??TT?HHHHTTSEEEEEEEE--EEE?-? 3IEQ|A PF02543.10_CmcH_NodU_seed 11 425 !Q:8,8|10,10|12,13|19,19|21,21|40,41|49,52|54,61|67,68|78,78|81,82|94,94|104,104|107,109|134,137|142,142|157,157|185,189|201,201|214,214|219,220|223,223|242,252|254,257|259,259|261,264|267,273|284,286|288,290|305,306|311,311|314,314|316,316|320,321|332,332|345,347|350,353|368,368|370,375|378,380|384,384|388,407|411,411|415,416|422,423 Q:0,7|9,9|11,11|14,18|20,20|22,39|42,48|53,53|62,66|69,77|79,80|83,93|95,103|105,106|110,133|138,141|143,156|158,184|190,200|202,213|215,218|221,222|224,241|253,253|258,258|260,260|265,266|274,283|287,287|291,304|307,310|312,313|315,315|317,319|322,331|333,344|348,349|354,367|369,369|376,377|381,383|385,387|408,410|412,414|417,421|424,424 HHHHTTTT?S?E--EEEEE?S?SSSEEEEEEEEETTEEEE--EEEEEGG----G?-------HHHHH--HHHHHHTTS?TT-?HHHHHHHGGGS?TTEEEETTS?TT???TTSSSSHHHHHHHHHHHHHHHSSS????EEEE-EETTTTEEEEEESS?HHHHHHHHHHHHHHHHHHHHHHHHHHT----?SEEEEESGGGG?HHHHHHHHTSTT?SEEE??TT?STTHHHHHHHHHHHHHTT?----??????S?--?B?S????HH-------HHHHHHHHHT???B??-TTHHHHHHHHHHTT??EEEE?SS?B?SSS??SSEEEEEESS?SSHHHHHHHTTS???TT????EEEEGGGHHHHBSS?S??---?SS???EEB?HHH--------------------HTT?GGG??TTSEE??E 3VES|A PF02545.9_Maf_seed 12 227 !Q:1,1|5,8|19,23|27,38|42,43|59,59|64,64|67,77|91,91|96,98|116,118|129,129|138,142|150,154|166,166|174,175|190,191|198,199|210,226 Q:0,0|2,4|9,18|24,26|39,41|44,58|60,63|65,66|78,90|92,95|99,115|119,128|130,137|143,149|155,165|167,173|176,189|192,197|200,209 S?EEE????HHHHHHHHHT?--??EEE?????????--?SSS?-HHHHHHHHHHHHHHH-HHTT?TT-----------SEEEEEEEEEEET-TEEE???SSHHHHHHHHHHHTTSE---EEEEEEEEEE?SSEEEEEE-----EEEEEEE??-??HHHHHHHHHTT?GGGSTTS??SSGGGGGTEEEEES-?HHHHTT??HHHHHHHHTT???-------------? 1EXC|A PF02547.10_Queuosine_synth_seed 110 555 !Q:0,2|5,9|14,14|17,18|20,23|37,46|49,50|52,55|61,61|69,70|73,73|82,83|85,85|91,125|130,135|140,145|147,149|151,161|165,172|176,177|182,182|185,186|189,189|194,203|206,212|215,219|227,230|233,234|236,236|238,238|245,246|249,260|266,346|351,352|364,364|373,397|402,402|414,414|418,419|433,433|435,441|443,448|452,474|480,486|489,493|496,496|503,505|508,508|519,519|535,543|549,549|554,554 Q:3,4|10,13|15,16|19,19|24,36|47,48|51,51|56,60|62,68|71,72|74,81|84,84|86,90|126,129|136,139|146,146|150,150|162,164|173,175|178,181|183,184|187,188|190,193|204,205|213,214|220,226|231,232|235,235|237,237|239,244|247,248|261,265|347,350|353,363|365,372|398,401|403,413|415,417|420,432|434,434|442,442|449,451|475,479|487,488|494,495|497,502|506,507|509,518|520,534|544,548|550,553 ???TT?????GGGB?SS??S----SGGGSEEEEEETT----------TT--E----EEEEE-GGGGGGG??TT?EEEEEEEE??S?EEEEB?------?-----??------------------??EEEE------EEEE------E---E-----------TTE--------EEE--EEES?TT??TT?EEEE----------ET-------TE-----EEEEEEE---?TT--S?E-EEEEES??HH------------HHHHH??-----????-?????-------------------??--------------??-???????--?----?--?????????GGGG??HHHHHHHHHHT?EEEEEEEE??????????---????????????EEEE?HHHHHHHHHHH-HHT??EEEESHHHHHHHH-H-------H------TTS---------??-----------?SSEEE???????SS--???SS?SEEEEE???TT?HHHHHHHHHH?HHHHHHHHHHHHHTT-------??BSTTS?EEEE? 1WDI|A PF02548.10_Pantoate_transf_seed 117 302 !Q:0,8|19,21|23,24|30,31|44,44|50,50|59,60|66,67|82,87|95,96|100,101|117,118|121,121|128,129|131,135|149,150|158,158|166,176|196,196|204,205|215,216|218,219|222,222|229,229|231,231|238,238|245,252|254,255|257,259|262,269|272,272|278,283|296,296|299,299 Q:9,18|22,22|25,29|32,43|45,49|51,58|61,65|68,81|88,94|97,99|102,116|119,120|122,127|130,130|136,148|151,157|159,165|177,195|197,203|206,214|217,217|220,221|223,228|230,230|232,237|239,244|253,253|256,256|260,261|270,271|273,277|284,295|297,298|300,301 ?--??---?HHHHHHHHHH---T??EEEEE??SHHHHHHHHHTT?SEEEE?TTHHHHTT??SSSTT??HHHHHHHHHHHHHT??----SSEEEEE??TTS?-SSHHHHHHHHHHHHH--TT?SEEEEE??G-----GGHHHHHHHHHTT??EEEEEES?GGGHHHH???-????-?-SHHHHHHHHHHHHHHHHHT?SEEEEES??HHHHHHHHH--H?-SS?EEEESS?S?SSEEEE?HHHHTT--?-----S-?S???TT?????---TT?SSHHH------HHHHHHHHHHHT?SS?GG 3VAV|A PF02550.10_AcetylCoA_hydro_seed 5 230 !Q:0,7|9,11|19,20|23,23|28,29|35,37|55,58|63,63|66,68|71,71|81,81|86,86|89,92|107,110|117,118|126,136|146,146|153,154|157,159|169,169|181,181|189,189|191,195|199,205|210,212|219,220 Q:8,8|12,18|21,22|24,27|30,34|38,54|59,62|64,65|69,70|72,80|82,85|87,88|93,106|111,116|119,125|137,145|147,152|155,156|160,168|170,180|182,188|190,190|196,198|206,209|213,218|221,229 -----???B??-HHHHHTT??TT?EEEE??SSSTT???SHHHHHHHHHHHHHTTT????EEEE?SS???TT-THHHHHHTT?EEEE-ES????HHHHHHHHTTSSEE????GGGHHH--HHHTTSS??-------??EEEEEESEE?TTSEEE??SB--?BTHHHHHHH?SEEEEEEETTS?GGGTTSB?B?????TTS???-???SSTT???SBSSEE??GGGEEEEEE 3S8D|A PF02551.10_Acyl_CoA_thio_seed 9 150 !Q:6,6|8,9|18,20|24,28|40,44|46,46|72,73|91,91|93,95|99,99|122,128|132,133|138,143 Q:0,5|7,7|10,17|21,23|29,39|45,45|47,71|74,90|92,92|96,98|100,121|129,131|134,137|144,149 HHHTTS?S??SEEEEESS???TTT?????SEEEEEEEESS-???-S?HHHHHHHHHHHTTSSSGGGGGGGGT??TTSTTEEEEEEEEEEEE?S???TTS?EEEEEEEEEEETTEEEEEEEEE-------ETT??EEEE------EEEEEE 3U0A|A PF02552.11_CO_dh_seed 6 180 !Q:0,23|26,28|39,39|47,47|49,52|55,55|85,85|87,88|95,95|108,110|115,117|125,126|141,141|144,144|149,149|153,154|161,164 Q:24,25|29,38|40,46|48,48|53,54|56,84|86,86|89,94|96,107|111,114|118,124|127,140|142,143|145,148|150,152|155,160|165,179 ???????-----????????????EE???HHHHHHHHHH?SSEEEEE?S??-?HH-HHHHHHHHHTSSSEEEEETTHHHHHHHTT?G--GGSEEE?HHHHHHHHHSTT???TTSS???SEEEEES??HHHHHHHHHHHHHH?TT?EEEE?SSS??TTSSEE????GGGHHHHHHHHHHHH 3CF4|G PF02556.9_SecB_seed 114 217 !Q:0,25|27,27|42,42|50,51|54,57|71,85|87,88|106,107|110,122|138,145|147,147|149,150|152,152|184,193|202,204|206,216 Q:26,26|28,41|43,49|52,53|58,70|86,86|89,105|108,109|123,137|146,146|148,148|151,151|153,183|194,201|205,205 ????????-----------------?E-EEEEEEEEEEEEEE?TTHHHHT--TS????EEEEEEEEEEEEE---------------E--TTEEEEEEEEEEEEEET--TE-------------EEEEEEEEEEEEEEE--------E-S??H-HHHHHHHHTHHHHHHHHHHHHHHHHHHHHHT??????????HHHHHHHH---H------????? 1QYN|A PF02557.12_VanY_seed 63 239 !Q:2,2|15,15|23,24|26,32|34,44|46,46|49,52|61,62|68,98|101,102|108,108|114,114|120,133|146,175|184,184|190,203|205,206|216,218|220,222|224,230|235,236 Q:0,1|3,14|16,22|25,25|33,33|45,45|47,48|53,60|63,67|99,100|103,107|109,113|115,119|134,145|176,183|185,189|204,204|207,215|219,219|223,223|231,234|237,238 GG?EEHHHHHHHHHH-HHHHHHT--T?----??E-----------E-EE????HHHHHHHH--HHHHS------------------?????????????TT??GGGGT?EEEEE?GGGTT----??--------SGGGGGSHHHHH------------------------------HHHHGGGG-TEEES--------------S-?GGGHHHHSS???T---T-------EEEE-?GG 4F78|A PF02558.11_ApbA_seed 98 219 !Q:4,5|17,18|21,21|24,24|26,30|35,35|37,37|44,44|49,49|57,63|69,71|74,74|78,89|93,95|101,101|103,103|110,110|115,115|120,121|124,133|138,139|142,144|146,146|149,149|157,162|164,165|167,167|175,179|184,190|195,198|201,204|206,210 Q:0,3|6,16|19,20|22,23|25,25|31,34|36,36|38,43|45,48|50,56|64,68|72,73|75,77|90,92|96,100|102,102|104,109|111,114|116,119|122,123|134,137|140,141|145,145|147,148|150,156|163,163|166,166|168,174|180,183|191,194|199,200|205,205|211,218 EEEE??SHHHHHHHHHH--HH-TT?E-----EEEE?S?HHHHHH-HHHH?EEEEETT-------EEEEE???EE?GGG?----------?TTS???SEEEE?S?HHHHHH-HHHH-HGGG??TT---?------EEEE??SS---S?TH-HHHTTTS-----?G--G-GEEEEEE?-???EEEE-------TTEE----EE?---S--???EEEEESSG 3GHY|A PF02559.11_CarD_CdnL_TRCF_seed 152 154 !Q:1,2|5,5|7,12|32,38|41,41|43,46|49,50|56,56|59,64|66,69|71,73|81,81|87,87|89,91|93,95|99,104|107,107|110,119|121,124|130,135 Q:0,0|3,4|6,6|13,31|39,40|42,42|47,48|51,55|57,58|65,65|70,70|74,80|82,86|88,88|92,92|96,98|105,106|108,109|120,120|125,129|136,153 T??TT?E------EEETTTEEEEEEEEEEEES-------SS?E----EE--EEEEE?GG------G?---E---EEEEGGG-GGGEE-E???S--?SSS-?????TT?SH----------H----HHHHH------HHHHHHHHHHHHHHHHHH 3MLQ|E PF02560.9_Cyanate_lyase_seed 25 75 !Q:0,1|6,7|34,34|52,52|58,58|71,74 Q:2,5|8,33|35,51|53,57|59,70 ??SSSS??SHHHHHHHHHHHHHHHHHHHHHHHHT?SEEEEEEEEEEEEEEEE?TTSSE-EEEEEEEEEEEE???? 2IVG|A PF02561.9_FliS_seed 6 133 !Q:0,21|43,47|53,53|70,70|80,81|107,107|129,132 Q:22,42|48,52|54,69|71,79|82,106|108,128 ???-????????----??????TTHHHHHHHHHHHHHHHHHHH-----HHHTT?HHHHHHHHHHHHHHHH-HHHHHHHHH--HHHTTHHHHHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHHHHHHHH???? 3IQC|A PF02562.11_PhoH_seed 164 255 !Q:0,4|17,19|21,21|23,26|32,33|53,54|57,57|65,65|67,69|71,73|75,78|81,89|104,128|137,138|154,155|157,157|164,164|169,170|182,182|185,185|192,213|223,224|226,227|234,235|239,242|248,248|254,254 Q:5,16|20,20|22,22|27,31|34,52|55,56|58,64|66,66|70,70|74,74|79,80|90,103|129,136|139,153|156,156|158,163|165,168|171,181|183,184|186,191|214,222|225,225|228,233|236,238|243,247|249,253 ?????SHHHHHHHHHHH---H?S----EEEEE??TTSSTTHHHHHHHHHHHHT--TS?SEEEEEE?S?-?T---T????SS?????????TTTHHHHHHHTTTS------------------------?TTHHHHHH--HTTSEEEEEGGGGTT??B?SEEEEE?SGGG??HHHHHHHHTTB?TT?EEEEEE????????-??-?-----????HHHHHHTTT-?T--TEEEEE??GGG????HHHHH-HHHHH? 3B85|A PF02563.11_Poly_export_seed 183 156 !Q:9,16|19,19|28,28|31,53|56,56|58,72|74,74|78,88|96,103|118,118|121,122|137,138|141,143|146,148 Q:0,8|17,18|20,27|29,30|54,55|57,57|73,73|75,77|89,95|104,117|119,120|123,136|139,140|144,145|149,155 HHHHHHHHT?--?????TT?EEEEEETT?HH-----------------------HH?T---------------T?SSS---------?-TTTSSEE------??TTSEEEETTTEEEE?TT??HHHHHHHHHHHHTT--TS---SS?-?EEEEEEE 2W8H|A PF02565.10_RecO_C_seed 157 205 !Q:0,2|20,22|25,28|31,32|43,43|46,50|53,53|55,60|62,65|82,85|89,89|93,94|96,97|100,100|107,124|131,134|151,166|173,175|179,184|196,196|199,200 Q:3,19|23,24|29,30|33,42|44,45|51,52|54,54|61,61|66,81|86,88|90,92|95,95|98,99|101,106|125,130|135,150|167,172|176,178|185,195|197,198|201,204 ???THHHHHHHHHHHHHHHH?-?BT???-HH--HHHHHHHHHH-HH-----HT?S------S?--?HHHHHHHHHHHHHHHT????SSB?TTT??B??TT?EEEEET------------------TTEEEE????STTEEEHHHHHHHHHT???-------------SHHHHH---HHH------HHHHHHHGGGS?SS??HHHH 1U5K|A PF02566.14_OsmC_seed 173 155 !Q:0,1|3,8|10,11|36,36|38,38|43,44|48,51|57,63|65,67|70,70|72,75|78,86|88,89|95,99|109,113|115,116|118,122|137,137|141,141|145,147|150,151 Q:2,2|9,9|12,35|37,37|39,42|45,47|52,56|64,64|68,69|71,71|76,77|87,87|90,94|100,108|114,114|117,117|123,136|138,140|142,144|148,149|152,154 ??S?-----S??HHHHHHHHHHHHHHHHHHHHHHHT-T?GGGE--EEE----EEEEE-------E---EE?S----SS---------S??EEEEE-----EEEEEEESS-----S??H-----HHHHHHHHHHHHTS?TTT-TTB-??SS??EEE 1LQL|A PF02567.11_PhzC-PhzF_seed 14 337 !Q:4,4|9,10|19,20|22,26|28,29|41,41|44,44|50,60|71,71|78,79|96,102|118,128|145,146|149,151|153,153|166,167|171,181|183,183|186,187|196,196|203,203|207,207|211,214|219,222|231,233|240,240|248,249|251,251|254,255|260,260|266,266|282,282|284,286|297,297|302,303|314,317|329,329 Q:0,3|5,8|11,18|21,21|27,27|30,40|42,43|45,49|61,70|72,77|80,95|103,117|129,144|147,148|152,152|154,165|168,170|182,182|184,185|188,195|197,202|204,206|208,210|215,218|223,230|234,239|241,247|250,250|252,253|256,259|261,265|267,281|283,283|287,296|298,301|304,313|318,328|330,336 EEES?SSTT?-SEEEEEEE??T-----T??HHHHHHHHHHH?SS?EEEEE?---------?SSSSEEEEEE?SSSEES??HHHHHHHHHHHHHHHT?-----?SEEEEEEETTEEEEE-----------EEEEETTEEEEEEEEE??EE???B?HHHHHHHHHHTT??GGG-----------B?TT??BEEEESSS?EEEEEB?TTS?STT????HHHH----HHHHHHHT???EEEEEE?TTSSEEE--E?EE?-TTSS?SEESS?HHHHHHHHHHHHHTT?S???SSEEEEEEEE?TTTT??EEEEEEEEEE----TTEEEEEEEEE?EEEEEEE 1SDJ|A PF02568.9_ThiI_seed 8 204 !Q:9,10|36,36|41,41|60,61|63,63|71,71|83,87|112,113|117,120|127,128|139,141|143,143|146,146|151,152|165,165|172,190|202,203 Q:0,8|11,35|37,40|42,59|62,62|64,70|72,82|88,111|114,116|121,126|129,138|142,142|144,145|147,150|153,164|166,171|191,201 TTTEEEEEE??SSSHHHHHHHHHHHBTEEEEEEEEE?TTTS?HHHHHHHHHHHHHHGGGS--S?EEEEEEE?HHHHHHHHHHS----?GGGHHHHHHHHHHHHHHHHHHHTT??EEE????SSSTTS??HHHHHHHGGG?-?S?EE?TTTT??HHHHHHHHHHTT?HHHHTS???????????????????HHHHHHHHTTS?? 3BL5|A PF02569.10_Pantoate_ligase_seed 7 314 !Q:0,0|4,5|14,14|21,22|24,25|32,32|34,36|48,48|59,61|65,66|70,70|75,77|90,90|95,97|103,103|106,113|115,123|152,153|178,180|186,188|190,190|194,194|196,197|203,204|228,231|233,234|248,251|254,254|259,259|271,277|279,279|282,282|285,286|298,304 Q:1,3|6,13|15,20|23,23|26,31|33,33|37,47|49,58|62,64|67,69|71,74|78,89|91,94|98,102|104,105|114,114|124,151|154,177|181,185|189,189|191,193|195,195|198,202|205,227|232,232|235,247|252,253|255,258|260,270|278,278|280,281|283,284|287,297|305,313 ?EEE??HHHHHHHH-HHHHHT--T??EEEEEE?S???HHHHHHHHHHH-HHSSEEEEEE???GGG??TTS?GGGS???HHHHHHHHHTTT?SEEE???HHHHS?TT????????S---------GGGTTTGGGSTTHHHHHHHHHHHHHHHH??SEEEEEGGGHHHHHHHHHHHHHTT???EEEEE???B?TTS?B??GGGGG??HHHHHHTHHHHHHHHHHHHHHHT----T??BHHHHHHHHHHHH----HT?TTEE-EEEEEEEETTT-?----?B?SB?SS?-EEEEEEEEETT-------EEEEEEEEE 3IME|A PF02570.10_CbiC_seed 155 257 !Q:3,3|14,20|22,23|26,26|30,31|44,44|50,51|56,56|58,61|63,76|86,86|90,93|106,106|110,110|113,121|124,125|128,128|141,141|153,154|156,165|168,168|175,175|187,188|191,192|194,197|203,205|219,221|223,226|229,230|235,235|238,240|253,256 Q:0,2|4,13|21,21|24,25|27,29|32,43|45,49|52,55|57,57|62,62|77,85|87,89|94,105|107,109|111,112|122,123|126,127|129,140|142,152|155,155|166,167|169,174|176,186|189,190|193,193|198,202|206,218|222,222|227,228|231,234|236,237|241,252 HHH-HHHHHHHHHH??----?T--TS?HHH--HHHHHHHHHHHT?GGGGG--GEEE?T----T--------------HHHHHHHHH-HTT?--?EEESSHHHHHHS?GGG?SS------???EE??TT?TTHHHHHHHHTS?HHHHGGGGGGG--G---------?TT?EEEESS?HHHHHHHHHHH--HT--T????SEEEE???SSSSHHHHHHHHH---H?--?TT??EEEE?SS???HHHHHHHHHHHH???? 2AFV|A PF02572.10_CobA_CobO_BtuR_seed 173 235 !Q:1,4|14,14|31,39|47,51|53,58|65,65|69,76|78,88|93,94|96,96|98,103|109,109|112,113|130,147|150,150|165,170|174,174|184,184|187,187|190,190|196,196|199,201|208,208|219,219|224,224|226,229|234,234 Q:0,0|5,13|15,30|40,46|52,52|59,64|66,68|77,77|89,92|95,95|97,97|104,108|110,111|114,129|148,149|151,164|171,173|175,183|185,186|188,189|191,195|197,198|202,207|209,218|220,223|225,225|230,233 B????EEEEESSSS?HHHHHHHHHHHHHTTT?-------?EEEEESS??-?-S??----HHHHHH-GGG--------T----------?EEEE??T-T????--STTHH-HH--HHHHHHHHHHHHHHTT-----------------?TT?SEEEEETHHHHHHT------TSS?HHHHHHHHH-TS?TT?EEEEE?SS?-?HHHHHH?SEEEEEEEEE?GGGG-T????TTTT? 4HUT|A PF02574.11_S-methyl_trans_seed 16 372 !Q:4,5|8,11|23,42|46,48|54,54|70,70|75,75|77,77|80,80|83,104|122,130|133,145|152,166|173,173|177,177|195,196|202,207|209,209|220,221|228,231|237,239|244,244|247,249|262,263|273,273|293,295|301,304|307,308|311,312|315,315|326,326|331,332|352,354|357,358 Q:0,3|6,7|12,22|43,45|49,53|55,69|71,74|76,76|78,79|81,82|105,121|131,132|146,151|167,172|174,176|178,194|197,201|208,208|210,219|222,227|232,236|240,243|245,246|250,261|264,272|274,292|296,300|305,306|309,310|313,314|316,325|327,330|333,351|355,356|359,371 HHTT??EE????HHHHHHHHTSS?-------------------TTT???THHHH?HHHHHHHHHHHHHTT?SEEE?S?TT?SS??------??????????????HHHHHHHHHHHHHHHTT---------TT------------?EEEEEE?------------??HHHHTT?HHH-HHHHHHHHHHHHHHHHT-?SEEEE?--?-?S?HHHHHHHHHH--HGGGTS---?EEEEE??-BTTB?TT???HHHHHHHHHTTT-?SEEEEESSS?HHHHHHHHHHHHHHHHTTT???EEEEE??--SB??TT??TT?GGGSTTTTTS?GGGB??HHHHHHHHHHHHHHTEEEE???TT??HHHHHHHHHHTHH 3BOL|A PF02575.11_YbaB_DNA_bd_seed 139 114 !Q:6,6|11,14|35,38|48,49|56,56|61,61|63,68|70,70|96,98|105,113 Q:0,5|7,10|15,34|39,47|50,55|57,60|62,62|69,69|71,95|99,104 HHHHHH-HHHH----HHHHHHHHTTSEEEEEEGGG----TEEEEEETT??EEEEEE?GGGG-G------S?HHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHT?-??--??? 1J8B|A PF02576.12_DUF150_seed 40 179 !Q:6,6|8,8|32,39|42,45|63,65|67,72|74,75|82,83|88,89|99,99|107,107|110,110|114,114|127,132|138,139|143,143|146,146|148,163|169,169|172,173|176,176 Q:0,5|7,7|9,31|40,41|46,62|66,66|73,73|76,81|84,87|90,98|100,106|108,109|111,113|115,126|133,137|140,142|144,145|147,147|164,168|170,171|174,175|177,178 HHHHHH?S-SSEEEEEEEEEETTEEEEEEEEE------?-SS?-??HHHHHHHHHHHGGGTTT?-?S???--?S-?EEEEEE??SSSS??SSHHHHHHH?SEEEEEE?SS?SSS?SEEEEEEEEEET------TEEEE--EEE?SS?E----------------EEEEE?SS??SS?EE 1IB8|A PF02577.9_DNase-RNase_seed 112 222 !Q:2,3|10,10|14,21|31,32|35,39|46,47|59,61|64,67|70,71|100,100|108,110|112,112|114,129|132,164|169,169|182,185|195,195|198,198|201,216 Q:0,1|4,9|11,13|22,30|33,34|40,45|48,58|62,63|68,69|72,99|101,107|111,111|113,113|130,131|165,168|170,181|186,194|196,197|199,200|217,221 EE--EEEEEE?TTT-?-----?EEEEEEETT--SS-----EEEEEE??HHHHHHHHHHH---HT-???SS??HHHHHHHHHHHTTEEEEEEEEEEEETTE-EEEEEEE---E-E???????????----?EE---------------------------------EEEE?HHHHHHHHHHHT--??EEEEHHHHH-HH?EE??--------------HHHHH 1VJL|A PF02578.10_Cu-oxidase_4_seed 132 403 !Q:2,2|4,8|10,18|22,29|31,34|37,39|41,41|43,45|47,47|54,57|65,69|72,73|75,83|88,88|90,92|95,96|100,101|104,119|122,122|125,131|135,135|143,143|151,151|154,162|178,179|185,186|194,194|200,203|212,212|220,229|233,237|242,243|245,246|250,250|253,257|262,262|266,271|276,276|279,281|288,311|318,318|332,335|337,337|343,360|365,366|369,369|371,373|377,382|386,395|402,402 Q:0,1|3,3|9,9|19,21|30,30|35,36|40,40|42,42|46,46|48,53|58,64|70,71|74,74|84,87|89,89|93,94|97,99|102,103|120,121|123,124|132,134|136,142|144,150|152,153|163,177|180,184|187,193|195,199|204,211|213,219|230,232|238,241|244,244|247,249|251,252|258,261|263,265|272,275|277,278|282,287|312,317|319,331|336,336|338,342|361,364|367,368|370,370|374,376|383,385|396,401 EE?S----?S---???--?GGG-------?S????SS---S-S??-H-HHHHHH----HHHHHHH-----HT??G---------GGEE?B???SS??EEE??GG----------------GT-TT-------TTS?GGGSBTT?SEEEESS-SS?--------EEEEEESSSEEEEEE--ETTTT--EEEEEEE?HHHHH----TTHHHHHH-HHHHHTS??-------?GGG?----EEEE??B??TTT?EE?----HHHH-HHH------GGGS?TT???SEEEEE------------------------TTEEEE?HHHHHHHHHHHTT??--G-GGEEE-------???--------BTTT?-TT-T???TTT------TTT??-----??-EEEEEE? 1XAF|A PF02579.12_Nitro_FeMo-Co_seed 179 149 !Q:2,2|5,8|10,11|13,15|17,17|19,19|24,26|30,33|36,36|45,46|48,64|70,75|77,77|84,84|89,91|94,97|102,103|105,106|118,118|120,120|125,132|134,135|138,139|142,142 Q:0,1|3,4|9,9|12,12|16,16|18,18|20,23|27,29|34,35|37,44|47,47|65,69|76,76|78,83|85,88|92,93|98,101|104,104|107,117|119,119|121,124|133,133|136,137|140,141|143,148 SS?SS?---S??S---S?S?EEEE---EES----SS-SEEEEEEE??S----------------?TTTSS------S?STTHHH-HHHH---TT?--?EEEE??S--SHHHHHHHHHH-T?EEEE--?----?S??HH--HH-HHHHHT 1RDU|A PF02580.11_Tyr_Deacylase_seed 37 201 !Q:14,17|21,28|34,37|47,47|51,57|71,73|75,81|84,84|86,86|88,88|90,90|96,97|104,104|109,109|111,111|117,117|119,119|123,124|143,144|146,174|178,179|183,184 Q:0,13|18,20|29,33|38,46|48,50|58,70|74,74|82,83|85,85|87,87|89,89|91,95|98,103|105,108|110,110|112,116|118,118|120,122|125,142|145,145|175,177|180,182|185,200 EEEEEEEEEEEEEE----TTE--------EEEEE----SSEEEEEEE?BTT-----??HHHHHHHHHHHHH???B-----??SS?S-S?B?TTTTT-?EEEEEE?GGGG?B?SSSSS?B?TTB??HHHHHHHHHHHHHHHHTT?-S----------------------------?EEE??SSS??EEEEEEEEEEEEEEEG 2OKV|A PF02581.12_TMP-TENI_seed 89 268 !Q:4,5|10,22|34,43|45,46|52,59|61,66|68,70|86,87|90,91|93,93|100,102|109,113|116,123|129,129|131,133|136,138|145,145|147,147|162,164|170,172|176,178|185,185|188,200|206,206|213,213|215,224|226,230|237,238|247,254|258,258 Q:0,3|6,9|23,33|44,44|47,51|60,60|67,67|71,85|88,89|92,92|94,99|103,108|114,115|124,128|130,130|134,135|139,144|146,146|148,161|165,169|173,175|179,184|186,187|201,205|207,212|214,214|225,225|231,236|239,246|255,257|259,267 EEEE??TTTS?------------HHHHHHHHHHT----------T-?SEEEE???-----S----??H---HHHHHHHHHHHHHHH--HT--T?EEEEES--?HHHHHH-----HT?-------SEEEE?T---TS?-?HHHHHH-H?TTSEEEEEESSHHH---HHHHH---HHT?--SEEEEE?SS????????--???HHHHH-HHHHHH?S----------S----?EEEESS??TTTHHHHH--------TTT?SEEEESHHH 3QH2|A PF02583.12_Trns_repr_metal_seed 147 109 !Q:8,8|16,18|25,25|30,30|33,35|37,39|56,59|81,87|93,95 Q:0,7|9,15|19,24|26,29|31,32|36,36|40,55|60,80|88,92|96,108 HHHHHHHH-HHHHHHH---HHHHHH-HHHH-HT---T??-HHHHHHHHHHHHHHHH----HHHHHHHHHHHHHHHHHHHHH?------HHHHH---HHHHHHHHHHHHH 2HH7|A PF02585.12_PIG-L_seed 137 358 !Q:11,11|24,28|30,31|33,33|41,87|90,92|103,110|114,115|120,121|125,130|136,136|138,138|142,142|144,155|160,165|172,174|179,225|227,227|233,233|241,245|251,253|257,289|292,298|303,307|310,310|312,329|332,332|336,336|341,345|347,348|353,355 Q:0,10|12,23|29,29|32,32|34,40|88,89|93,102|111,113|116,119|122,124|131,135|137,137|139,141|143,143|156,159|166,171|175,178|226,226|228,232|234,240|246,250|254,256|290,291|299,302|308,309|311,311|330,331|333,335|337,340|346,346|349,352|356,357 EEEESSTTHHH-HHHHHHHHHHHH-----T--T?EEEEEES---------??----?-------------------------------TT???SSSTTGGGST--------TTT??HHHH--HHH------HHHHH-H-HHT-T?--------???EETT------STTSSB???SSSS????-------------------------------------------S?BGGGS?HHHHHHH-----HHHHH---HHH---?---?-------------------------SE-------EEEE?----TT?T------------------TT?HHH-HHHH-----H--HHHH---HH 2X9L|A PF02586.9_DUF159_seed 164 764 !Q:0,8|12,18|20,20|22,23|31,32|37,82|84,86|91,95|106,169|173,175|179,202|204,204|210,210|212,259|261,261|267,281|283,283|285,286|289,291|293,294|298,301|305,307|310,310|312,312|321,324|327,332|334,376|380,384|386,396|400,402|404,557|565,565|567,567|571,573|575,635|638,638|646,654|657,661|666,667|669,686|688,688|691,691|694,697|706,715|718,719|725,725|733,739|747,749|751,752|760,762 Q:9,11|19,19|21,21|24,30|33,36|83,83|87,90|96,105|170,172|176,178|203,203|205,209|211,211|260,260|262,266|282,282|284,284|287,288|292,292|295,297|302,304|308,309|311,311|313,320|325,326|333,333|377,379|385,385|397,399|403,403|558,564|566,566|568,570|574,574|636,637|639,645|655,656|662,665|668,668|687,687|689,690|692,693|698,705|716,717|720,724|726,732|740,746|750,750|753,759|763,763 ???--?---EEE?------S?H--HHHHTTT??GGGB????----------------------------------------??S???EEEE?----TTSEEEEEEE----------------------------------------------------------------ETT---EEE------------------------E-EEEEB?B-----?----?---????---------------------------???B?EEEHH---------------H-H--TT--?T--TTH----HHH---HH?E-EEEEESEE----EE------E?----------------------?????-------?------?EEE-----E-----------EET---T------?--??-----------------------------------------------------------------------------------------------------------------------------------------------EEEEEEE?S?GGG??-S-------------------------------------------------------------SB?EEEEEEE?-------?GG-----GGGT-?S------------------E-EE?EE--?-HHHHHHHH---------?TT??HHHHH-HHHHHHB?-----?GGGEEEE---E??GGGGSTT???G 1ZN6|A PF02589.10_DUF162_seed 209 320 !Q:3,3|13,14|20,20|22,33|47,96|100,109|113,113|117,118|121,121|125,126|129,131|133,159|165,165|169,178|181,182|195,197|201,202|217,221|224,224|229,229|242,258|264,266|270,286|288,304|306,308|310,310|312,312 Q:0,2|4,12|15,19|21,21|34,46|97,99|110,112|114,116|119,120|122,124|127,128|132,132|160,164|166,168|179,180|183,194|198,200|203,216|222,223|225,228|230,241|259,263|267,269|287,287|305,305|309,309|311,311|313,319 HHH-HHHHHHHTT-?EEEEE?T------------TTHHHHHHHHHTT?------------------------------------------------?EEE?--------?TTS?GGG??TT?EEE??SS???H---------------------------HHHHH?SEE----------EE??SEEETTTTEEEE???TTT??GGGGTSSSEEEEEE-----EG-GGEE-SSHHHHHHHHHH-----------------HHHTT???EEE-----------------E??-??????????????S---S?S-EEEEEEE 2G40|A PF02590.12_SPOUT_MTase_seed 30 166 !Q:0,0|9,12|32,37|44,58|73,75|90,91|107,108|115,116|119,121|128,128|135,135|138,140|162,165 Q:1,8|13,31|38,43|59,72|76,89|92,106|109,114|117,118|122,127|129,134|136,137|141,161 ?EEEEEEES????HHHHHHHHHHHHHHTTTSE------EEEEEE???????????????HHHHHHHHHHHTTS--?TTSEEEEEEEEEEE??HHHHHHHHHHHHTTT??EEEEEE??SS???HHHHHH?SEEEES?SS???HHHHHHHHHHHHHHHHHHHTS???? 1NS5|A PF02591.10_DUF164_seed 93 66 !Q:11,11|20,20|24,27|29,29|33,34|36,37|45,45|49,50|53,55|58,58|62,63 Q:0,10|12,19|21,23|28,28|30,32|35,35|38,44|46,48|51,52|56,57|59,61|64,65 HHHHHHHHHHH-HGGGSEEE?BTT----B?TTT??B??HHHHHHH-HHS--SS--?EE?TTT??EE 3NA7|A PF02594.11_DUF167_seed 29 82 !Q:0,0|12,12|17,17|23,23|26,31|36,39|58,60|69,69 Q:1,11|13,16|18,22|24,25|32,35|40,57|61,68|70,81 ?SSEEEEEEEEE?SSSS?EEEEE?SS-----?EEEE????SSHHHHHHHHHHHHHHHT???TTTEEESS?TTSSEEEEEEES 1N91|A PF02595.10_Gly_kinase_seed 6 381 !Q:0,0|5,8|13,14|30,30|38,42|57,57|66,66|72,72|80,80|84,84|100,102|106,107|111,113|128,128|135,136|139,141|153,153|157,157|161,161|163,164|173,174|182,182|194,199|216,217|240,243|246,246|264,265|269,269|287,287|293,294|298,304|319,320|328,340|348,350 Q:1,4|9,12|15,29|31,37|43,56|58,65|67,71|73,79|81,83|85,99|103,105|108,110|114,127|129,134|137,138|142,152|154,156|158,160|162,162|165,172|175,181|183,193|200,215|218,239|244,245|247,263|266,268|270,286|288,292|295,297|305,318|321,327|341,347|351,380 ?EEEE????BTTS??HHHHHHHHHHHHHTT?TTSEEEE?????SSTTHHHHHHHHHT?EEEEEEEE?TTSSE-EEEEEEE?TTS?EEEEETHHHHBGGGS--?GGG??TTT???HHHHHHHHHHHHTT?SEEEEE??SB???STTHHHHHHTT?EEE?TTS?B??SSTTGGGS??EEETTSS?THHHHSEEEEE??????SSSTTSHHHHHTGGGT??HHHHHHHHHHHHHHHHHHHHHS????TT?TTTTGGGGHHHHHHHTT??EEE?HHHHHHHHTTHHHHHHH?SEEEE??EES???????HHHHHHHHHHHHTT??EEEEEEE?????????????SEEEEEE???TTSTTHHHHHHHHHHHHHHHHHHHHHHHHH 3CWC|A PF02597.15_ThiS_seed 145 106 !Q:3,3|12,14|23,23|26,26|36,39|41,41|44,44|51,51|53,53|57,57|60,65|76,78|80,84|86,86|88,91|94,94|101,105 Q:0,2|4,11|15,22|24,25|27,35|40,40|42,43|45,50|52,52|54,56|58,59|66,75|79,79|85,85|87,87|92,93|95,100 EEE?THHHHHHS---SSEEEEEE?TT?BHHHHHHHH----H-HH?GGGGGS?B?SSS?TT------SSBEEEETTB???T-----T?B?--?TT?EEEEES????? 2K5P|A PF02598.12_Methyltrn_RNA_3_seed 23 436 !Q:12,13|15,17|37,38|45,105|108,117|131,131|139,145|154,159|163,165|168,169|172,172|182,182|186,217|226,226|230,230|233,239|242,242|251,264|268,268|273,275|278,283|285,288|305,310|317,317|321,321|333,355|360,360|367,382|386,388|390,405|410,410|416,416|420,422 Q:0,11|14,14|18,36|39,44|106,107|118,130|132,138|146,153|160,162|166,167|170,171|173,181|183,185|218,225|227,229|231,232|240,241|243,250|265,267|269,272|276,277|284,284|289,304|311,316|318,320|322,332|356,359|361,366|383,385|389,389|406,409|411,415|417,419|423,435 EEEEEEETTTTT--T???HHHHHHHHHHHHHHHHHTT??EEEEEE?------------------------------------------------------------SS???-------HHHHHHHHHHHHS?HHHHHHH?---???GGGGGGGG??????TTS?-?SS??TT?EEEEEEEEE?SSS--------------------------------EEEESSSS?EEE?SS----???SS?EEEEEEEE-------------?SSS?EEEE???SS------S????EEEEEEEEHHHHHHHH??----SEEEEE?TTS?BTTTSHHHHHH-----------------------HHTT?SEEEEE??-------------?SSS???S???-------------SEEE-BSSTT?SSS???HHHHHHHHHHHHH 1K3R|A PF02599.11_CsrA_seed 137 71 !Q:0,0|9,9|14,16|18,18|20,20|31,32|36,39|46,47|51,51|58,63|69,70 Q:1,8|10,13|17,17|19,19|21,30|33,35|40,45|48,50|52,57|64,68 ?EEEEEETT?EEEE---T-T-TEEEEEEEEE--TTE----EEEEEE??TTS?EEEHHH------HHHHT?? 1VPZ|A PF02600.11_DsbB_seed 184 216 !Q:0,20|35,39|42,42|48,51|55,57|80,82|84,85|89,90|94,94|120,123|126,130|132,141|145,145|153,153|158,195|215,215 Q:21,34|40,41|43,47|52,54|58,79|83,83|86,88|91,93|95,119|124,125|131,131|142,144|146,152|154,157|196,214 ?------????????-?????HHHHHHHHHHHHHH-----HH-HHHTT----TTT???SHHHHHHHTTTTTSTTTTTTTS?--S--SSS-?TTS-HHHHTTSSHHHHHHHHHHHHHHHHS--??SS?--??B-----?????TTS?GGGGSST-TTTT?-???-???????-?--??----------------???HHHHHHHHHHHHHHHHHTT? 2ZUQ|A PF02602.10_HEM4_seed 137 385 !Q:6,8|10,11|16,17|22,23|25,25|27,27|31,40|48,48|53,55|57,57|63,63|71,71|78,103|106,106|109,115|117,117|121,121|134,136|138,138|140,147|150,157|160,161|164,164|170,170|172,172|179,187|191,192|194,196|200,204|207,207|210,214|218,219|223,223|225,229|233,235|242,245|249,250|252,278|289,290|293,304|308,309|317,317|328,335|341,341|345,345|356,356|360,360|363,366|370,372|381,382 Q:0,5|9,9|12,15|18,21|24,24|26,26|28,30|41,47|49,52|56,56|58,62|64,70|72,77|104,105|107,108|116,116|118,120|122,133|137,137|139,139|148,149|158,159|162,163|165,169|171,171|173,178|188,190|193,193|197,199|205,206|208,209|215,217|220,222|224,224|230,232|236,241|246,248|251,251|279,288|291,292|305,307|310,316|318,327|336,340|342,344|346,355|357,359|361,362|367,369|373,380|383,384 HHHHHH---H--HHTT-?EEEE??S?E-EEE------????HHHHHHH-HTGG---G?SEEEE?SHHHHHH-HHHHHH--------------------------HH?SS??-----S?EEE-ESSHHHHHHHHH---H-T------??EE------??SS??SH-HHHHT?H-HHHHHT--------?SSS-?E---EEE-----EE?SS?--??HHH--HHH-H-----HTT--?EEEEEE---?EEE--E????----------------------?TTHHHHHHHH--TT?----------?EEE??SHHHHHH-HHHHHGGGHH--------HHTTS?EEE-SSHHHHHHHH-HTT?SS----EEE?--SSSSHHHH--HH 1JR2|A PF02603.11_Hpr_kinase_N_seed 84 152 !Q:2,12|17,20|22,23|25,25|30,32|38,38|40,43|45,45|48,49|56,57|60,61|64,66|71,71|73,73|82,82|85,85|88,88|98,100|103,105|109,109|112,117|129,130|134,135|137,138 Q:0,1|13,16|21,21|24,24|26,29|33,37|39,39|44,44|46,47|50,55|58,59|62,63|67,70|72,72|74,81|83,84|86,87|89,97|101,102|106,108|110,111|118,128|131,133|136,136|139,151 HH-----------HHHH----H--T?EEEE--?GGGTT?B-???S?EE??HHHHTT??TT??TT---SEEE-E?HHHHHHHH-HS?HH-HHTTHHHHH??-TT???EEE?TT?--???HHHHHHHHHTT??EEE??S-?HHHHHHHHHHHHH 1KNX|A PF02604.14_PhdYeFM_antitox_seed 156 93 !Q:9,9|25,27|32,32|36,37|45,49|58,60|77,82|89,90 Q:0,8|10,24|28,31|33,35|38,44|50,57|61,76|83,88|91,92 SEEEEHHHH-HHTHHHHHHHHHHHT?-?EEEE?TTS?-EEEEEEH-----HHHHHHHH---HHHHHHSHHHHHHHHH------HHHHHH--TT 3D55|A PF02605.10_PsaL_seed 21 190 !Q:0,3|9,9|14,14|17,17|22,22|36,36|39,40|69,69|103,111|114,151 Q:4,8|10,13|15,16|18,21|23,35|37,38|41,68|70,102|112,113|152,189 ????EEGGG?TTBB?EE?HHHH?HHHHHHHHTSTTT?TT??HHHHHHHHHHHHHHHHTHHHHHHSTTTT-STTHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS------???SS-------------------------------------?GGGSHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHH 2WSE|L PF02606.9_LpxK_seed 173 546 !Q:0,0|7,10|21,22|29,33|37,37|39,41|43,45|48,49|60,61|78,82|88,90|92,92|95,98|100,101|106,106|113,121|123,123|128,128|137,138|140,140|142,142|152,152|165,169|171,192|199,199|202,202|206,215|223,229|236,237|247,247|250,251|256,256|259,259|261,262|265,271|273,273|277,278|280,330|333,333|336,336|342,343|348,364|366,366|368,376|379,379|382,382|387,387|390,391|393,401|420,420|423,424|431,432|435,439|442,445|448,460|463,463|465,465|472,472|474,474|476,482|484,505|507,513|524,526|541,546 Q:1,6|11,20|23,28|34,36|38,38|42,42|46,47|50,59|62,77|83,87|91,91|93,94|99,99|102,105|107,112|122,122|124,127|129,136|139,139|141,141|143,151|153,164|170,170|193,198|200,201|203,205|216,222|230,235|238,246|248,249|252,255|257,258|260,260|263,264|272,272|274,276|279,279|331,332|334,335|337,341|344,347|365,365|367,367|377,378|380,381|383,386|388,389|392,392|402,419|421,422|425,430|433,434|440,441|446,447|461,462|464,464|466,471|473,473|475,475|483,483|506,506|514,523|527,540 ?GGGGHH----HHHHHHHHHH--HHHHHH-----HTT?S-??B??-SS?-EEEEEESBSS??SHHHHHHHHHHHTTTS----?EEEEE???S?SS?---S--EEEE-EETTEE--------?S?HHHH?HHHHHHHH--H?T-TSEEEEESS-HHHHHHHHHHHH?---?S----------------------EEEEET?TT?TTB?--------?SEEEEEE-------EHHHHT??BTTTSSBSS?GG--GGGG?SE-E--EE-------E?TTT--S???------?---------------------------------------??SS?EE-EEEEE--EEEE-----------------E?T---------TS?EE?GGGG-TT??E---------EEEESSTHHHHHHHHHHH-HT??EEEEEE??TT???--SS????TT---??--------EE-E?HHHHTT?T-T?------T----------------------T-------EEEEEEEEEE---TTHHHHHHHHHHTT----?- 4EHX|A PF02607.12_B12-binding_2_seed 255 100 !Q:0,0|15,15|26,36|41,41|43,52|74,74|79,79 Q:1,14|16,25|37,40|42,42|53,73|75,78|80,99 ?HHHHHHHHHHHHTT?TTHHHHHHHH-----------HHHT-T--------??HHHHHHHTHHHHHHHHHHHHH-TTSS?HHHHHHHHHHHHHHHHHHHH 2I2X|B PF02608.9_Bmp_seed 13 394 !Q:0,0|10,10|32,33|35,35|42,43|45,58|74,74|95,105|109,109|116,118|120,134|143,143|164,164|170,186|190,191|202,202|211,215|218,218|225,225|227,227|230,230|244,244|247,248|253,254|256,256|275,279|287,288|291,291|295,295|299,299|309,309|325,328|331,331|336,336|344,361|363,364|368,368|388,390|393,393 Q:1,9|11,31|34,34|36,41|44,44|59,73|75,94|106,108|110,115|119,119|135,142|144,163|165,169|187,189|192,201|203,210|216,217|219,224|226,226|228,229|231,243|245,246|249,252|255,255|257,274|280,286|289,290|292,294|296,298|300,308|310,324|329,330|332,335|337,343|362,362|365,367|369,387|391,392 ?EEEEEESSS?TTSSSHHHHHHHHHHHHHHHT--T?EEEEEE??S--------------GGGHHHHHHHHHHTT?SEEEEESGGGHHHHHHHHHH?----------TTS?EEEESS???S?--------------TTEEEEEE?HHHHHHHHHHHHHHHHHHTT?SEEEE-----------------EES??STTTHHHHHH-HHHHHHHH?----TT?EEEEEE?S?SS?HHHHHHHHHHHHH-TT??EEEE--E?HHHHHHHHHHHHHHHHTT?--??EEEEEES??GG-GGB?SSS?BSEEEEEEE?HHHHHHHHHHHHHHT-???TT?EEEE?TTTTSEE??----------------S??TTS?HHHHHHHHHHHHHHHTTSS???SS? 2FQY|A PF02609.11_Exonuc_VII_S_seed 148 53 !Q:18,18|20,20 Q:0,17|19,19|21,52 HHHHHHHHHHHHHHHHTT?S?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 1VP7|A PF02610.10_Arabinose_Isome_seed 38 369 !Q:0,2|5,5|8,8|16,17|21,21|44,45|47,47|53,55|57,57|72,72|82,83|85,87|98,101|103,103|109,110|112,112|115,116|120,121|128,129|146,147|154,154|157,157|180,180|187,190|193,193|197,199|208,209|215,215|226,227|245,245|251,251|253,253|278,278|283,284|287,288|291,291|294,296|306,306|308,308|315,315|334,335|337,337|348,349|352,353|359,359|362,364 Q:3,4|6,7|9,15|18,20|22,43|46,46|48,52|56,56|58,71|73,81|84,84|88,97|102,102|104,108|111,111|113,114|117,119|122,127|130,145|148,153|155,156|158,179|181,186|191,192|194,196|200,207|210,214|216,225|228,244|246,250|252,252|254,277|279,282|285,286|289,290|292,293|297,305|307,307|309,314|316,333|336,336|338,347|350,351|354,358|360,361|365,368 ?-?GG-GG?EEEEEEB??SSS?TTHHHHHHHHHHHHHHHHHHHT??S-SEEEE???B?SHHHHHHHHHHHHH?TTEEEEEEE??S???THHHHHHHHH??--S?EEEEE??S?SS??TTT??HHHHHH??HHHHHHHHHHHHHHTT??EEEEES?TT?HHHHHHHHHHHHHHHHHHHHTT?EEEEES?-??TT?STT???HHHHHHHH??EEEEE?HHHHHHHHHT??HHHHHHHHHHHHHHSEE?GGGST-T?TTHHHHHHHHHHHHHHHHHHHHHT?SEEE??TT??TT?SS???HHHHHHHHT-T?EEESTT?HHHHHHHHHHHHHTTTSS--S?EEEEEEEEEE??TT??EEEEE?SS???GGGB 2HXG|A PF02611.10_CDH_seed 24 245 !Q:0,2|21,22|29,30|33,36|45,45|51,51|59,61|65,65|74,75|94,96|106,106|110,110|112,113|115,116|123,123|135,138|141,142|145,145|148,148|151,151|153,157|161,162|168,168|176,178|189,189|194,194|205,205|209,213|221,221|228,229|236,236|239,240|243,245 Q:3,20|23,28|31,32|37,44|46,50|52,58|62,64|66,73|76,93|97,105|107,109|111,111|114,114|117,122|124,134|139,140|143,144|146,147|149,150|152,152|158,160|163,167|169,175|179,188|190,193|195,204|206,208|214,220|222,227|230,235|237,238|241,242 ???HHHHHHHHTHHHHHHHHS??TTSSEE--ET----TTTEEEEE?SSSSS?EEEEESS???STT?GGGGSTTS??HHHHHHHTTHHHHHHHTS???GGGEEEEEB?GGG?S??S??EEEEEB?HHHHHHHHTTG----GG??SS?EE?TT?B-----TTB??EEEEE?HHHHHHS--?HHHHHHHHST-TTTT?GGGEEEEEEE?TTS?----EEEEEEE?BTTTTB??BGGGGB?TT?-TT??- 2POF|A PF02613.10_Nitrate_red_del_seed 270 201 !Q:6,8|15,39|43,46|53,54|58,60|63,63|74,75|78,79|82,83|91,97|100,106|109,109|124,135|153,167|169,169|183,188|195,196 Q:0,5|9,14|40,42|47,52|55,57|61,62|64,73|76,77|80,81|84,90|98,99|107,108|110,123|136,152|168,168|170,182|189,194|197,200 HHHHHS?-?GGGSSS?------------------------HHH----HHHHHH--HHT???SS?HHHHHHHHHT-?SS??SS??BHHHHHS-------TT---??--SS?HHHHHHHHHHHHTT??????--????TTBHHHHHHHHHHHHHT---------------T?HHHHHHHHHHHTH------HHHHHH--HHHH 1N1C|A PF02614.9_UxaC_seed 42 521 !Q:0,2|5,5|7,7|11,13|17,19|32,32|36,36|38,41|49,51|53,53|61,64|66,66|78,79|85,85|89,89|104,104|120,131|134,139|141,143|161,161|163,166|185,186|188,188|191,193|201,201|203,208|211,213|218,219|221,222|227,227|231,231|247,249|271,272|280,280|282,289|301,301|305,308|332,332|339,339|342,345|353,353|358,359|362,367|383,385|396,396|409,412|422,425|427,431|434,434|436,436|452,452|456,463|465,465|470,470|490,493|498,500 Q:3,4|6,6|8,10|14,16|20,31|33,35|37,37|42,48|52,52|54,60|65,65|67,77|80,84|86,88|90,103|105,119|132,133|140,140|144,160|162,162|167,184|187,187|189,190|194,200|202,202|209,210|214,217|220,220|223,226|228,230|232,246|250,270|273,279|281,281|290,300|302,304|309,331|333,338|340,341|346,352|354,357|360,361|368,382|386,395|397,408|413,421|426,426|432,433|435,435|437,451|453,455|464,464|466,469|471,489|494,497|501,520 ???SS?T-TTT??-SHH---HHHHHHHTTTTS?EEE?S????HHHHHHT???S?HHHHHHS----S?SHHHHHHHHTT??GGGTT?TTS?HHHHHHHHHHHGGG?TTSHHHHHHHHHHHT------------TT---???S???SHHHHHHHHHHHHHHHT-S----GGGSHHHHHHHTTEEEEE??B?TT???HHHHHHH-H-----?TT??-SEEE??B??HHHH?TTS-TTHHHHHHHHHHHHT???SSHHHHHHHHHHHHHHHHHTT??EEEEEES-S????????HHHHHHHHHHH-HTT????HHHHHHHHHHHHHHHHHHHHHHT?EEEEEE?EE????HHHHHHH?SSSS??EE????-?HHHHHHHHHHHHTTT???EEEEEESSGG-GHHHHHHHGGGS?--?TTSTTSEEE????G-----GG?S-HHHHHHHHHHHHHHS?GGG????????S?TTTT-HHHHHHHHHHHHHHHHHHH----TTSS???HHHHHHHHHHHHTHHHHHHT 3IAC|A PF02615.9_Ldh_2_seed 8 348 !Q:3,3|20,21|40,40|64,66|80,80|84,84|114,116|118,118|138,139|141,142|144,144|146,147|150,151|153,154|156,159|165,166|170,171|177,177|182,182|186,205|209,211|219,222|224,224|228,228|256,257|261,263|267,269|272,273|282,282|288,288|307,309|312,312|314,317|333,333 Q:0,2|4,19|22,39|41,63|67,79|81,83|85,113|117,117|119,137|140,140|143,143|145,145|148,149|152,152|155,155|160,164|167,169|172,176|178,181|183,185|206,208|212,218|223,223|225,227|229,255|258,260|264,266|270,271|274,281|283,287|289,306|310,311|313,313|318,332|334,347 EEE?HHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHTT?GGGSGGGHHHHHHHHHHTSSBSS???EEEEEETTEEEEE?TTB?HHHHHHHHHHHHHHHHHHHSEEEEEEEEE???S?THHHHHHHHTTTSEEEEEE??S--S?B??TT??S??B????EEEEE??SSS-?EEEEE?SBSS?TTT????????????????????SSS???SSTTTTT??--B?BTT?SSSTTSHHHHHHHHHHHHHHHTTTTTS??GGG???TTS---TT??EEEEEEEE?GGGTS?HHHHHHHHHHHHHHHHTS???TT?S????TTHHHHHHHHHHHHH?EEEEHHHHHHHHHH 1XRH|A PF02616.9_ScpA_ScpB_seed 11 284 !Q:6,7|11,12|28,28|33,43|63,83|114,116|119,126|130,152|166,167|170,283 Q:0,5|8,10|13,27|29,32|44,62|84,113|117,118|127,129|153,165|168,169 HHHHTT??TTS??HHHHHHHHHHHHHHH-HHTT???-------?HHHHHHHHHHHHHHHHHHS?-?????????--????????TTHHHHHHHHHHHHHHHHHHHHHHHHHHHH---TS????????STT??????---??--???------?HHHHHHHHHHHHH??EE?????------------------------------------------------------------------------------------------------------------- 4I99|C PF02617.12_ClpS_seed 194 105 !Q:0,7|10,12|17,18|35,38|55,55|59,59|63,63|79,84|89,100 Q:8,9|13,16|19,34|39,54|56,58|60,62|64,78|85,88|101,104 ????--??EE---EEEE??SSSBHHHHHHHHHHHH-???HHHHHHHHHHHHHHSE-EEE-EEE?HHHHHHHHHHHHHHH------HHTT?---------??EEEE 3GQ1|A PF02618.11_YceG_seed 195 523 !Q:5,5|8,9|25,25|27,34|37,40|42,42|50,51|53,60|66,66|69,71|80,81|85,142|145,153|157,157|160,161|165,176|184,191|197,199|204,206|212,212|214,214|229,229|234,236|239,239|246,246|248,248|253,255|259,267|271,271|282,284|288,290|298,316|320,322|324,326|341,343|346,347|361,361|363,369|371,380|388,389|391,393|395,404|406,419|422,424|427,427|429,436|439,439|444,444|447,447|450,450|453,455|465,477|481,503|516,522 Q:0,4|6,7|10,24|26,26|35,36|41,41|43,49|52,52|61,65|67,68|72,79|82,84|143,144|154,156|158,159|162,164|177,183|192,196|200,203|207,211|213,213|215,228|230,233|237,238|240,245|247,247|249,252|256,258|268,270|272,281|285,287|291,297|317,319|323,323|327,340|344,345|348,360|362,362|370,370|381,387|390,390|394,394|405,405|420,421|425,426|428,428|437,438|440,443|445,446|448,449|451,452|456,464|478,480|504,515 EEEEE?TT??HHHHHHHHHHTTSSS?H--------HH----H-HHHHHHH--T-???-???EEEEE?TT-??HHHHHHHH--HTT--------------------------------------------------------??SB?-----?-?EEE?TT??HHH------------HHHHHHH--------HSTTS--?HHHH---HHHHH?H-HHHHHHHHHSTTTS?GGGG?--TT?SSTTTT?S?SEEE???SSS?-------?HHH-HHHHHHHHHH---HHT---GGGHHHH-------------------HHT---T?-?HHHHHHHHHHHHHH??-SS??HHHHHHHHHHHHH-T-------T?-----????HHHHHHH--T---T?-------??S-----------???TT---GG-G-??----?TT?TTTS?SS?SS?SS???HHHHHHHHS?-????-----??EEE?---?-??---------???--?EEESSHHHHHTT?---??? 4IIW|A PF02621.9_VitK2_biosynth_seed 131 367 !Q:5,5|23,31|33,43|45,46|52,53|63,63|66,67|70,71|82,82|89,89|91,92|95,95|101,103|108,125|128,129|131,132|135,140|146,146|159,159|162,170|175,178|191,195|199,207|211,211|217,234|241,245|260,260|262,263|265,265|277,277|279,279|281,284|293,293|304,305|315,317|322,322|326,328|335,335|341,341|343,343|348,349 Q:0,4|6,22|32,32|44,44|47,51|54,62|64,65|68,69|72,81|83,88|90,90|93,94|96,100|104,107|126,127|130,130|133,134|141,145|147,158|160,161|171,174|179,190|196,198|208,210|212,216|235,240|246,259|261,261|264,264|266,276|278,278|280,280|285,292|294,303|306,314|318,321|323,325|329,334|336,340|342,342|344,347|350,366 EEEEE?SSHHHHHHHHHHHTTSS-------??S-----------S?-EEEEE??HHHHHHHHH-TT??SE--EEEEHHHHTT?TTTEEE?S--SS?EEESS???EEEE------------------SS??S??TT?-----EEEES?TTSHHHHHHHHH?SS?--------EEEE??--GGGHHHHHHTTS-----SSE---------EEE?TTHHH------------------HGGGGT?----EEEEEHHHHHHHHH-S--S?EEEEEEEEEGG-G?H----HHHHHHHH-HHHHHHHHHH--HSGGGGHHH---HHHH?TTS--?HHHHHH-HHHHH?S-HHHH??HHHHHHHHHHHHHHHHH 2NXO|A PF02622.10_DUF179_seed 181 301 !Q:0,0|2,2|4,5|7,7|9,9|19,25|28,28|30,30|32,33|37,37|40,50|52,52|62,70|72,103|106,120|122,122|127,131|134,134|139,147|152,166|168,168|170,172|175,192|195,197|199,203|209,209|217,219|223,231|234,234|237,237|240,240|242,242|248,249|254,254|259,259|264,265|268,277|283,284|288,290|298,300 Q:1,1|3,3|6,6|8,8|10,18|26,27|29,29|31,31|34,36|38,39|51,51|53,61|71,71|104,105|121,121|123,126|132,133|135,138|148,151|167,167|169,169|173,174|193,194|198,198|204,208|210,216|220,222|232,233|235,236|238,239|241,241|243,247|250,253|255,258|260,263|266,267|278,282|285,287|291,297 ?T-T--S?S?SSSSEEEEE?----??BT-T-B??EEE?SS--??--?----B?HHHHHHHHT---------S?-------------------------------SS??------???????S?BEES----?SB-TTTS----??---EEEE?--?-----------S?S---SS-------------??--?SS---S-----SEEEE?TTHHHHH---HTS?-??-----SS?EE?EE?B?THHHH??HHHH-HHHT?EEEE??HH----------HHTTS-?SSH---HHHHHHH??? 2EW0|A PF02623.10_FliW_seed 83 142 !Q:2,2|5,5|11,11|13,14|20,21|23,23|29,29|38,38|41,41|43,44|49,49|54,54|57,62|71,72|76,81|91,97|100,102|106,106|109,109|113,113|126,129|132,135 Q:0,1|3,4|6,10|12,12|15,19|22,22|24,28|30,37|39,40|42,42|45,48|50,53|55,56|63,70|73,75|82,90|98,99|103,105|107,108|110,112|114,125|130,131|136,141 EE?TT?BTTBT-T??EEEEE--E-SSTTS?EEEEEESS?TT?E--EEEE?GGGT?TT??????HHHHHHTT??SGG------GEEEEEEEE?-----?SS---GGG?EE?SSS?EEEETTTTEEEE???-SS????TTEESS 2AJ7|A PF02624.11_YcaO_seed 127 524 !Q:0,11|27,28|30,50|59,64|69,72|78,80|92,92|95,96|101,107|114,121|124,138|147,151|153,153|158,159|165,165|169,186|189,199|229,233|238,242|244,244|247,257|262,264|266,266|281,282|290,298|301,304|311,328|335,338|345,345|359,360|368,420|425,426|430,430|436,436|440,441|443,443|448,452|454,454|457,472|479,479|488,491|495,495|497,505|509,510|518,518|521,523 Q:12,26|29,29|51,58|65,68|73,77|81,91|93,94|97,100|108,113|122,123|139,146|152,152|154,157|160,164|166,168|187,188|200,228|234,237|243,243|245,246|258,261|265,265|267,280|283,289|299,300|305,310|329,334|339,344|346,358|361,367|421,424|427,429|431,435|437,439|442,442|444,447|453,453|455,456|473,478|480,487|492,494|496,496|506,508|511,517|519,520 ??????????-?THHHHHHHHHHHHHB??S??-----------------??EEEEHHHH------GGGB--??THHHH???HHHHHTHHHHH-HT??SSTT???????TTSEEE--------EE---------------EEEETTTT-----E-EEEE--EHHHH-SBT????--------------SS????????---TTEEEESSHHHHHHHHHHHHHHHHHHHHH-----HHHT---??B?BB----------?STTS---S?HHHHHHHHHHHHTT--EEEEEEE??-----?-TT-???EEEEEE------------------EESSSS????EEEEEE?SSHHHHHHHHHHH--HHHHHHH??-??????-------------------------------------???????HHHH??STT?GGGSB?TTS??B?GGGS?????S?HH----------------HHHHHH-HHHHHHHT??-?EEE-E??------?TTT?-SEEEEEE?TT??? 4BS9|A PF02625.11_XdhC_CoxI_seed 129 93 !Q:6,8|10,13|24,25|28,28|31,31|34,35|42,46|50,50|53,53|57,60|74,75|79,85 Q:0,5|9,9|14,23|26,27|29,30|32,33|36,41|47,49|51,52|54,56|61,73|76,78|86,92 HHHHSS???E----EEEEEEEEEE??SS?TT?EE--EEETTS---?-EES?SS-SSS----HHHHHHHHHHHHH--HHT?-----?EEEEEES 3ON5|A PF02626.10_AHS2_seed 160 361 !Q:3,6|8,8|23,26|29,30|38,41|46,46|49,49|52,52|65,74|77,79|82,88|91,91|93,93|97,97|100,100|108,108|110,111|117,117|124,124|126,130|134,134|136,138|148,155|159,162|165,165|170,171|175,178|180,183|185,207|212,215|222,222|224,224|229,229|232,232|238,238|249,249|264,265|267,275|280,284|288,288|299,300|302,302|311,311|317,317|320,321|327,327|333,333|343,344|347,348|355,356 Q:0,2|7,7|9,22|27,28|31,37|42,45|47,48|50,51|53,64|75,76|80,81|89,90|92,92|94,96|98,99|101,107|109,109|112,116|118,123|125,125|131,133|135,135|139,147|156,158|163,164|166,169|172,174|179,179|184,184|208,211|216,221|223,223|225,228|230,231|233,237|239,248|250,263|266,266|276,279|285,287|289,298|301,301|303,310|312,316|318,319|322,326|328,332|334,342|345,346|349,354|357,360 TTT????S?SSHHHHHHHHHHTT??--TT??EEEEESB--??EEEE-SS?EE-EEEEEEEEEEEE----------TT---EE-----??TT-S?EEE?SS?EEEEEEE-E--EEEEE-EEEETT?B-????BTT-B???BGGGTBSTT--------TTS-???TT?EEEB??STT????S????S?-----------------?????GGGS????SSSEEE-E-EEEE?SS?STTTB?HHHHHHHHHS?EEEEEEEETTEEEE--E----?????BSSS?---?GGG?SSTTEEEEEE??T-TEEEEETT-EEEEE?TT??SEEEE?EEEEE?GGGHHHHTT??TT-?EEEEEE??HHHH 3OPF|A PF02627.15_CMD_seed 215 104 !Q:17,20|23,23|40,41|44,45|47,47|55,56|59,59|63,64|66,68|78,78|84,88|94,95 Q:0,16|21,22|24,39|42,43|46,46|48,54|57,58|60,62|65,65|69,77|79,83|89,93|96,103 HHHHHHHHHTIIIIIIT-?-?SS?HHHHHHHHHHHHHHTT-?HH--H-HHHHHHH--HH-HTT??H---HHHHHHHHH-HHHHT----?HHHHH--HHHHHHHH 2QEU|A PF02629.14_CoA_binding_seed 70 122 !Q:0,0|3,4|14,15|19,19|30,32|38,38|41,42|45,46|50,58|74,84|89,95|109,109|112,112|118,119|121,121 Q:1,2|5,13|16,18|20,29|33,37|39,40|43,44|47,49|59,73|85,88|96,108|110,111|113,117|120,120 ?TT??EEEETTTSH--HHH-HHHHHHHHTT??-EEEEE?TT-?TT-?EET---------TEEEESSHHHHHHHH------?--??EEEE??----?HHHHHHHHHHHHH-TT?SEEEE??S? 2FPP|A PF02630.9_SCO1-SenC_seed 6 188 !Q:0,45|53,53|64,64|71,71|74,75|97,100|108,108|112,113|125,125|128,128|133,134|147,163|166,168|173,173|177,177|183,183|186,187 Q:46,52|54,63|65,70|72,73|76,96|101,107|109,111|114,124|126,127|129,132|135,146|164,165|169,172|174,176|178,182|184,185 -------------------???????????????---?????????EEEETTS?EEEGGGGTTS?EEEEEE?TT??THHHHHHHHHHHHHHHHHHHH????EEEEEES?TTT??HHHHHHHGGGS?TT?EEEE??HHHHHHHHHHTT?????????????????TT???EEEE?TTS?EEEEE?TT?? 2HRF|A PF02631.11_RecX_seed 147 194 !Q:0,10|12,12|15,18|32,34|49,49|52,53|63,63|67,68|74,74|80,81|83,87|92,114|124,124|127,132|134,152|168,169|176,193 Q:11,11|13,14|19,31|35,48|50,51|54,62|64,66|69,73|75,79|82,82|88,91|115,123|125,126|133,133|153,167|170,175 ????---??-?H-HH----HHHHHHHHHHTTS?-?HHHHHHHHHHHHHH-TT??HHHHHHHHH-HTT??HHHHH-HHHHH--H?--??HHHH-----------------------HHHHHHHHH?SS---???S-------------------HHHHHHHHHHHHHTT??HHHHTT---???--------???? 3E3V|A PF02632.9_BioY_seed 153 219 !Q:0,1|4,7|10,13|15,15|48,50|55,56|58,62|89,95|105,117|134,134|143,144|146,150|154,163|165,169|173,176|180,184|188,189|209,212|214,214 Q:2,3|8,9|14,14|16,47|51,54|57,57|63,88|96,104|118,133|135,142|145,145|151,153|164,164|170,172|177,179|185,187|190,208|213,213|215,218 ?-SS----SS--??B?STHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT???BTTT--B-?-?-SGGGGSTTHHHHHHHHHHHHHHHHHH-------HHTTGGGSS------------?HHHHHHHHHHHHTHHH-HHHHHHHH--H-----HHH----------T---??HHH----HHH-----HGG--GGHHHHHHHHHHHHHHHHH----H-HHSS 4DVE|A PF02633.9_Creatininase_seed 163 347 !Q:4,4|6,7|11,11|15,17|22,26|32,34|36,38|43,43|45,45|64,80|83,85|87,95|97,101|104,104|108,108|113,115|117,117|119,119|121,121|129,129|139,139|143,144|151,151|155,156|176,180|182,185|196,198|205,208|210,210|213,216|220,220|234,238|240,243|247,247|251,288|290,290|296,297|301,303|305,305|309,309|312,316|319,322|325,328|347,347 Q:0,3|5,5|8,10|12,14|18,21|27,31|35,35|39,42|44,44|46,63|81,82|86,86|96,96|102,103|105,107|109,112|116,116|118,118|120,120|122,128|130,138|140,142|145,150|152,154|157,175|181,181|186,195|199,204|209,209|211,212|217,219|221,233|239,239|244,246|248,250|289,289|291,295|298,300|304,304|306,308|310,311|317,318|323,324|329,346 GGGS?H--HHH-HHH---HHTS?--??EEEEE??-B???TTTB?S?HHHHHHHHHHHHHHHHHT----------------?EE???B??------?B--???HH-HHS?TTSS---S?B?B?HHHHHHH-HHHHHHHHH-HHT??EEEEEE?SGG--GHHHHHHHHHHHHHHHHHT-----T????EEEEEEGGGG???HHHHHH----H?TT????STT?SSSHHHHHHHHHH----?G----GGB?GGG----------------------------??????????S-SEEES??GGG---S?TTS?SS---??TT--??HH----HHHHHHHHHHHHHHHHHH- 3LUB|A PF02634.10_FdhD-NarQ_seed 203 463 !Q:1,2|10,10|13,20|29,29|31,52|69,72|77,78|85,121|124,135|137,137|139,143|146,164|167,169|171,229|234,252|254,254|268,268|270,270|278,279|286,287|289,293|296,297|299,300|324,333|336,352|354,370|372,374|377,381|388,388|390,390|402,403|410,410|412,412|424,424|433,446|449,450|456,457|462,462 Q:0,0|3,9|11,12|21,28|30,30|53,68|73,76|79,84|122,123|136,136|138,138|144,145|165,166|170,170|230,233|253,253|255,267|269,269|271,277|280,285|288,288|294,295|298,298|301,323|334,335|353,353|371,371|375,376|382,387|389,389|391,401|404,409|411,411|413,423|425,432|447,448|451,455|458,461 E??EEEEEEE-TT--------EEEEEEEE?S----------------------SSHHHHHHHHHHHHTS??-?GGGE--EEEEEE-------------------------------------TT------------T-E-----EE-------------------EE---E?--------------???----?????--?--??????--------??------?????HHHH??????--------?????B?GGGHHHHHHHHHT-S?SHHHHHS??EEEEEE--E-----TT--E--EEEEEEESSHHHHHHHHHHHHHT----------TS-----------------S----------------?S---SS-----EEEESS?B?HHHHHHHHHHT??EEEESS?B?HHHHHHHHHHT?EEEEEEET--------------TE--EEEEE?-GGGB? 2PW9|A PF02635.10_DrsE_seed 254 192 !Q:0,0|7,7|9,11|14,14|28,30|33,34|39,52|60,60|70,92|96,97|99,103|106,107|118,123|136,138|146,147|149,149|151,153|155,163|170,170|173,173|182,182|185,186 Q:1,6|8,8|12,13|15,27|31,32|35,38|53,59|61,69|93,95|98,98|104,105|108,117|124,135|139,145|148,148|150,150|154,154|164,169|171,172|174,181|183,184|187,191 ?EEEEEE?S?--TT-TBSHHHHHHHHHH---HH--HHTT-------------?EEEEEEE?GGGGGGGBS------------------?????TTS??H-----HH--HHHHHHHHHT----??EEEEHHHHHHHT???HHHHHHH--T?S???B--------?TTEEEE?TH-HHHHHHHH-SS--EEEEE 2PD2|A PF02636.12_Methyltransf_28_seed 157 606 !Q:13,16|18,30|37,37|52,59|63,76|83,83|86,98|110,126|131,161|170,171|173,174|177,177|179,184|186,207|217,217|222,223|228,260|266,267|269,269|277,315|319,335|337,339|343,344|346,346|348,349|351,352|354,368|379,411|414,414|419,419|430,432|439,490|501,502|508,513|516,516|519,519|521,523|527,542|546,546|550,559|562,564|568,568|575,576|583,586|591,591|596,599 Q:0,12|17,17|31,36|38,51|60,62|77,82|84,85|99,109|127,130|162,169|172,172|175,176|178,178|185,185|208,216|218,221|224,227|261,265|268,268|270,276|316,318|336,336|340,342|345,345|347,347|350,350|353,353|369,378|412,413|415,418|420,429|433,438|491,500|503,507|514,515|517,518|520,520|524,526|543,545|547,549|560,561|565,567|569,574|577,582|587,590|592,595|600,605 HHHHHHHHHHHHH----T-----------??EEEEES?TTSHHHHHHHHHHH--------HTT?-??----------SEEEEE?TT-------------SSSHHHHHHHH-----------------HHHS-------------------------------TTTGGGEE--E--ES-S?--?--S?---------------------EEEEEEEES?GGGS??EEEE---------------------------------EETTE--E-EEEEEEE?--------------------------------------TTS----------------?E---EEE--E-E??S--S---------------THHHHTTTTS???------------------------------TT?EEEE?HHHHHHHHHH---HHHEEE----------------------------------------------------EEEEEEEEEE-?HHHHT?-----TT?TT?S?--EEE----------------SSS?EES--------?-TT---SST-TSSEEE??EEHHHH----HHHH-HHTT---?EEEEEE 1ZKD|A PF02637.13_GatB_Yqey_seed 103 205 !Q:10,17|38,39|43,46|48,60|62,63|65,67|77,80|87,87|92,92|97,97|102,103|106,109|111,119|127,127|129,136|139,139|151,152|156,156|163,164|166,169|183,183|187,187|189,192 Q:0,9|18,37|40,42|47,47|61,61|64,64|68,76|81,86|88,91|93,96|98,101|104,105|110,110|120,126|128,128|137,138|140,150|153,155|157,162|165,165|170,182|184,186|188,188|193,204 HHHHHHHHHS--??----HHHHHHHHHTHHHHHTTTTT??TTS----S-------------S??H---HHHHHHHHH----HTTTSS?TTHH-HHSH-HHHH--HH-???H---------HHHHHHH-T?????--?SS?HHHHHHHHHHT?-HHH-HHHHTT??T----TSTHHHHHHHHHT-TSS?S-?--HHHHHHHHHHHS 2G5I|B PF02641.10_DUF190_seed 5 104 !Q:13,13|31,31|34,34|36,36|42,42|46,46|48,65|89,89|92,92|100,100 Q:0,12|14,30|32,33|35,35|37,41|43,45|47,47|66,88|90,91|93,99|101,103 SSEEEEEEEEETT?EETTEEHHHHHHHHHHH-TT?S?EEEEE?SEE-E??????????????????EEEEEEEEEHHHHHHHHHHHTTT?SS-SEEEEEE?EEE 2DCL|A PF02643.10_DUF192_seed 180 158 !Q:7,7|19,33|35,37|40,40|47,48|50,56|60,62|65,66|69,70|72,72|79,79|92,97|100,108|110,110|112,123|125,126|130,133|147,148|151,151 Q:0,6|8,18|34,34|38,39|41,46|49,49|57,59|63,64|67,68|71,71|73,78|80,91|98,99|109,109|111,111|124,124|127,129|134,146|149,150|152,157 EEEEEEE?SHHHHHHTTSS????----------?T---TE-EEEEEE--E-------EEE?-?EE??TT??S?EEEEEE?TTSBEEEEEEEE-----?TT?--???---E-E??----------S?-EEE----EEEEETTHHHHHT??TT?EEEETT 3PJY|A PF02645.11_DegV_seed 45 334 !Q:0,0|10,15|28,29|33,33|36,37|44,45|48,49|62,64|66,66|69,71|82,83|88,88|97,97|101,101|114,118|121,121|123,132|138,138|141,141|160,162|177,179|185,185|187,187|196,206|218,220|222,222|230,231|240,240|242,242|245,247|256,259|262,263|270,272|282,284|286,286|299,300|302,302|306,306|313,314|322,322|325,325|333,333 Q:1,9|16,27|30,32|34,35|38,43|46,47|50,61|65,65|67,68|72,81|84,87|89,96|98,100|102,113|119,120|122,122|133,137|139,140|142,159|163,176|180,184|186,186|188,195|207,217|221,221|223,229|232,239|241,241|243,244|248,255|260,261|264,269|273,281|285,285|287,298|301,301|303,305|307,312|315,321|323,324|326,332 ?EEEEEEGGG??-?--HHHHHHHTEEEE??EEE?SS-?EEEBTT--TB-?HHHHHHHHHTTT???E-EE???HHHHHHHHHH--HTTT?SEEEEEES?TTT?SHHHHHHHGGGG?----SS?E----------EEEEE?SS?HHHHHHHHHHHHHHHHTT???HHHHHHHHHHHTTT?--EEEEE?S?THHHHHHT-----------TTHHHHHHHSS???S?EEEEEET--TEEEEEEE?S?HH---HHHHHHHH----HH--HHHHTT???EEEEEEESS--?H-HHHHHHHHHHHH--H?TTE-EEEEEE??HHHHHHH?TT?EEEEEEE? 3FYS|A PF02649.9_GCHY-1_seed 121 336 !Q:0,18|33,34|36,36|38,40|43,43|57,61|64,67|80,81|84,87|90,90|97,100|112,116|118,118|135,135|139,141|160,164|166,166|181,181|191,228|241,244|247,253|267,267|270,271|273,275|290,292|307,311|314,314|326,326 Q:19,32|35,35|37,37|41,42|44,56|62,63|68,79|82,83|88,89|91,96|101,111|117,117|119,134|136,138|142,159|165,165|167,180|182,190|229,240|245,246|254,266|268,269|272,272|276,289|293,306|312,313|315,325|327,335 ?????----??????????SEEEEEEEEEEEEE??T-T---TS?EEEEEEEEEEEES---?-SS--??GGGGGHHHHHHH--HS--?-SS-EEGGGH----HHHHHHHHHHT-----T?SEEEEEEEEEEEEEEE?TTT?-?EEEEEEEEEEEEEEETTT-----E-EEEEEEEEEEEEEE?HHHHHHSSS??-----------------------------------?EEEEEEEEEEEE----SS--?--??HHHHHHHHHHHSS-EE??S???HHHHHHHHHHHHTS???HHHHHHHHHHHHHS?----TT-EEEEEEEEEEE?TTTSSEEEE 3D1T|A PF02650.9_HTH_WhiA_seed 23 90 !Q:33,34|39,39|52,52|56,56|65,70|72,73 Q:0,32|35,38|40,51|53,55|57,64|71,71|74,89 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?-GGGS?HHHHHHHHHHHH?TTS?HHHHHHTT------T??HHHHHHHHHHHHHHHT 3HYI|A PF02655.9_ATP-grasp_3_seed 18 216 !Q:14,15|17,30|35,45|56,62|64,65|68,69|73,90|95,97|108,108|125,142|152,155|175,177|179,180|189,195|199,201|212,213 Q:0,13|16,16|31,34|46,55|63,63|66,67|70,72|91,94|98,107|109,124|143,151|156,174|178,178|181,188|196,198|202,211|214,215 HTSHHHHHHHHTTT--S???----------?EESS??---------SSSEEEEESS???????B??SS??TTE------------------EEEE???SEEEEEEEEE-SSSEEEEEEEEEEEET------------------TEEEEEEES????HHHHHHHHHHHHHHHTTST---T??EEEEEEEE-------ESS---SEEEEEEESS??GG 3HO8|A PF02657.10_SufE_seed 7 129 !Q:7,7|25,28|38,38|40,40|45,45|53,53|57,57|59,60|85,86|93,95|109,109 Q:0,6|8,24|29,37|39,39|41,44|46,52|54,56|58,58|61,84|87,92|96,108|110,128 HHHHHHH?SSHHHHHHHHHHHHHHS????TTTSSGGGE-E?SSSS?EEEEEEE?SSS?E--EEEEEESSHHHHHHHHHHHHHTTT??HHHHHH???HHHHHHHTHHHHS?HHHHHHHHHHHHHHHHHHH 1MZG|A PF02661.13_Fic_seed 221 178 !Q:0,5|12,12|19,25|27,58|61,67|70,86|89,93|96,99|102,102|109,114|123,126|132,133|135,142|151,151|159,160|164,164 Q:6,11|13,18|26,26|59,60|68,69|87,88|94,95|100,101|103,108|115,122|127,131|134,134|143,150|152,158|161,163|165,177 ???---HHHHHH-HHHHHS------?S??????-----------???????????????SB------?SS??--------------?EE?????EE????TT-THHHHH------HHHHHHHH----HHHHH??S?-------HHHHHHHH-HHHHHHH??BSS?HHHHHHHHHHHHH 3ZC7|A PF02663.9_FmdE_seed 188 235 !Q:5,6|24,39|41,49|51,56|63,63|65,69|71,81|93,94|98,99|101,103|108,121|123,126|128,129|134,136|142,144|150,156|158,163|165,165|169,169|172,174|177,177|185,212|216,216|225,226 Q:0,4|7,23|40,40|50,50|57,62|64,64|70,70|82,92|95,97|100,100|104,107|122,122|127,127|130,133|137,141|145,149|157,157|164,164|166,168|170,171|175,176|178,184|213,215|217,224|227,234 HHHSS??HHHHHHHHHHHHHHHTS---------?------T---------T----??EEEEES?S-----S-----------SHHHHHHHHSS??TTT--T---SEEE?------------?S----S??EEEE---EETTT--?EEEEE-------E------E?GGG?SS?--HH-HHHHHTT?????-------------------????HHH-HHHHHHHG--GGGEEEEE 2GLZ|A PF02664.10_LuxS_seed 5 166 !Q:0,2|8,8|12,13|19,19|26,26|29,30|39,39|41,41|45,49|69,70|82,82|95,97|115,117|121,121|124,124|129,129|135,136|151,154|158,158|164,165 Q:3,7|9,11|14,18|20,25|27,28|31,38|40,40|42,44|50,68|71,81|83,94|98,114|118,120|122,123|125,128|130,134|137,150|155,157|159,163 ???GGGGB?GGG??SSEEE-EEEEEE?TT??EEEEEEEE?S?TTT?-???HHHHHHHHHHHHHHHHHHH?-BTTBEEEEEEE?TTSSEEEEEEES???HHHHHHHHHHHHHHHHT???GGG?TT?STTT?TTTTS??HHHHHHHHHHHHHH--??EEE?GGGGB?? 1J6W|A PF02665.9_Nitrate_red_gam_seed 66 237 !Q:2,2|28,28|32,32|34,37|41,42|44,44|71,71|79,79|81,81|88,88|122,123|150,150|152,158|177,177|180,180|188,189|217,220|226,228|234,236 Q:0,1|3,27|29,31|33,33|38,40|43,43|45,70|72,78|80,80|82,87|89,121|124,149|151,151|159,176|178,179|181,187|190,216|221,225|229,233 HH-HHHHHTHHHHHHHHHHHHHHHHHHH?GGG?S????GGG??T-THHHHHHHHHHHHHHHHHHHHHHHHS?TTTTTTT-S?HHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHS??HHHHHHHHHHHHHHHHHHHTHHHHTT?T-------TSHHHHHHHHHHHHHHTT?TT-GGGGGTT??HHHHHHHHHHHHHHHSGGGSGGGGGGG--??GGGGG??-SEEEE??? 1Y5I|C PF02668.11_TauD_seed 123 619 !Q:2,3|5,5|9,9|12,13|17,17|19,25|29,32|35,59|69,69|79,81|83,100|105,105|108,125|131,132|134,137|139,141|145,145|147,148|159,209|216,243|245,245|247,247|249,250|253,253|257,263|265,266|269,272|279,280|282,283|285,299|301,308|314,315|324,333|341,342|344,344|346,346|351,351|357,357|362,362|364,373|379,398|408,410|415,419|421,422|426,439|442,442|444,445|449,451|453,456|464,468|471,511|518,522|525,529|535,536|539,539|541,546|548,549|556,559|561,565|581,607|611,611 Q:0,1|4,4|6,8|10,11|14,16|18,18|26,28|33,34|60,68|70,78|82,82|101,104|106,107|126,130|133,133|138,138|142,144|146,146|149,158|210,215|244,244|246,246|248,248|251,252|254,256|264,264|267,268|273,278|281,281|284,284|300,300|309,313|316,323|334,340|343,343|345,345|347,350|352,356|358,361|363,363|374,378|399,407|411,414|420,420|423,425|440,441|443,443|446,448|452,452|457,463|469,470|512,517|523,524|530,534|537,538|540,540|547,547|550,555|560,560|566,580|608,610|612,618 EE--E?SSS-SS??EEE-S??-----SSS?-??SH-------------------------HHHHHHHHH-TTSSEEEEE---S??-------?-------?HHHH-HH------------------HHHHH--S---?B???SSS?E--ETTEEEEEEE---------------------------------------------------EESSSS???-----------------------??S?B?T--TT-TSS-------S??SE----EEEEEE--E??S---------------S?---??--EEEEE--TTHHHHTS?---------HHHHHHH--T-T?EEEE?HHHHS?GGGS?S----------SHHHH--------------------HHHHHHHHH???EEEE-----S--EEE?-------------TT-T??EEE???T----TTEEEET-----TS----------------------------------------?HHHHHH-----HH-----HHHHH--HT-T-----?G--GGEEEE???-S-----SEEEEEETTSEEEEE?-??----------------------?TTS?EEEEEEE 3O2G|A PF02670.11_DXP_reductoisom_seed 87 172 !Q:17,18|21,23|25,29|32,32|41,42|45,45|54,55|58,59|61,64|67,68|70,70|78,81|92,92|94,97|99,107|118,120|125,129|132,133|138,140|156,157|162,163 Q:0,16|19,20|24,24|30,31|33,40|43,44|46,53|56,57|60,60|65,66|69,69|71,77|82,91|93,93|98,98|108,117|121,124|130,131|134,137|141,155|158,161|164,171 EEEESTTSHHHHHHHHH--HH---H?----TT-TEEEEEEE?-SS?HHHHHHHH--HH--H--??SE--E-EESSHHH----HHHHHHHHHH-H----T?------??EEEEHHHHHH---HHHS?----TT??EEEE???SSTTHHHHHHHHHTT-?EEEE??THHHHTSH 1ONP|A PF02671.16_PAH_seed 121 96 !Q:16,16|25,25|29,34|37,37|44,59|61,64|68,68|70,70|72,76|78,80|85,87|92,92|95,96 Q:0,15|17,24|26,28|35,36|38,43|60,60|65,67|69,69|71,71|77,77|81,84|88,91|93,94 HHHHHHHHHHHHHHHH-HHHHHHHH?SSS?----?SS?HHHHHH----------------H----HHH-H?S-----S??-HHHH---HHHH-HS?- 1S5R|B PF02672.10_CP12_seed 39 76 !Q:0,54|63,63|71,71|74,75 Q:55,62|64,70|72,73 ???????????????????-?????????????????????????????--????HHHHHHHH?TTTTSTT-TS?? 3B1K|C PF02675.10_AdoMet_dc_seed 134 172 !Q:8,11|17,17|34,35|40,40|45,48|51,60|62,62|72,107|120,127|140,142|147,149|159,159|167,167 Q:0,7|12,16|18,33|36,39|41,44|49,50|61,61|63,71|108,119|128,139|143,146|150,158|160,166|168,171 EEEEEEES?--?HHHHT?HHHHHHHHHHHHHHHT??EEEE-EEEE?---SS----------S?EEEEEEETT------------------------------------EEEEEEEEGGGT--------EEEEEEEEESTT-??HHHH---HHHHHHHHT?SEEEEEE-EEEE 1TLU|A PF02676.9_TYW3_seed 42 322 !Q:12,21|28,28|30,30|42,44|52,52|54,54|56,57|65,116|125,146|157,158|162,182|189,190|214,214|217,217|221,245|251,251|253,255|265,279|282,285|317,318|320,321 Q:0,11|22,27|29,29|31,41|45,51|53,53|55,55|58,64|117,124|147,156|159,161|183,188|191,213|215,216|218,220|246,250|252,252|256,264|280,281|286,316|319,319 HHHHHHHHHHHH----------HHHHHT?S?GGGHHHHHHHH---HSTTEEE?S?B??EEEEEEE--------------------??????-----------------------???EEEEEESS?-------------------??HHHHHHHHTT??SSE---------------------EEEEEE??EEEEEESSHHHHHHHHHHHHHTT?TT?EEE????------------------???EEEEE?S-??EEEEEEETT---------------EE??-?HHHHHHHHHHHHHHHHHHHHHHHHHHHHGGG--G?? 2DRV|A PF02678.11_Pirin_seed 52 139 !Q:3,3|10,15|18,18|28,28|33,34|37,37|39,39|52,52|55,55|58,58|64,64|66,66|74,76|79,79|89,89|97,97|103,103|106,106|113,115|117,127|129,130 Q:0,2|4,9|16,17|19,27|29,32|35,36|38,38|40,51|53,54|56,57|59,63|65,65|67,73|77,78|80,88|90,96|98,102|104,105|107,112|116,116|128,128|131,138 EEE?GGGSEE------EE?SSEEEEESS?BTTB??SS?S?BTTEEEEEEEEE?TT?EE-EEEEE?S?EEEEEEE---ES-EEEEEESSS?EEEEETT?EEEEE?TT?EEEEEE???S-----------S??EEEEEEEE 1J1L|A PF02679.10_ComA_seed 30 291 !Q:0,1|7,17|25,29|44,44|50,50|58,58|74,74|79,79|89,90|93,93|95,95|107,108|113,114|118,120|128,131|140,140|147,169|178,179|195,195|201,202|206,207|213,213|216,218|220,220|222,222|233,233|235,237|245,246|249,253|264,264|267,268|287,287 Q:2,6|18,24|30,43|45,49|51,57|59,73|75,78|80,88|91,92|94,94|96,106|109,112|115,117|121,127|132,139|141,146|170,177|180,194|196,200|203,205|208,212|214,215|219,219|221,221|223,232|234,234|238,244|247,248|254,263|265,266|269,286|288,290 ??TTGGG?--?-??????EEEEESS---??HHHHHHHHHHHGGG?SEEEE?TTGGGGS?HHHHHHHHHHHHTTT?EEEE?HHHHHHHHH--TT?H-HHHHHHHHHHT??EEEE??SSS???HHHHHHH----HHHHHHTT?EEEEEE?---------------------?SSHHHHTT??HHHHHHHHHHHHHHT?SEEEE??TTT??SSTTB?TT---S?B?HHHHHHHHTT-S?--GGGEEEE??SH-----HHHHHHHHHH?TT??EEEEEGGGHHHHHHHHHT?SGG 1QWG|A PF02680.9_DUF211_seed 22 100 !Q:0,3|5,6|16,18|20,20|22,22|36,37|47,47|50,50|59,59|62,63|76,76|90,99 Q:4,4|7,15|19,19|21,21|23,35|38,46|48,49|51,58|60,61|64,75|77,89 ????S--EEEEEEEEE??-S?S?HHHHHHHHHHSTT??EEEEEEEEE?SS?EEEEEEEE?SS??HHHHHHHHHHTT?EEEEEEEEEEESS?????????? 2RAQ|A PF02682.11_AHS1_seed 158 317 !Q:0,4|8,8|10,15|23,25|27,30|32,37|44,47|58,65|70,70|84,85|90,102|105,106|110,113|117,120|124,124|128,130|140,165|177,177|179,199|210,212|224,224|232,232|242,244|247,249|251,253|255,257|260,260|265,265|286,286|293,294|296,299|301,302|304,304|307,307|311,313 Q:5,7|9,9|16,22|26,26|31,31|38,43|48,57|66,69|71,83|86,89|103,104|107,109|114,116|121,123|125,127|131,139|166,176|178,178|200,209|213,223|225,231|233,241|245,246|250,250|254,254|258,259|261,264|266,285|287,292|295,295|300,300|303,303|305,306|308,310|314,316 ?--?-EEE?S------TTEEEEE??-S?-??H------HHHHHH----HHHHHHHHHH?------?TTEE-EEEEETTEEEEEE?-TTTS------------?HH--HHH----HHH----HHH-HHH---HHHHHHTTE--------------------------EEEEEEESTTT?T---------------------THHHHHHHHT??-HHHHHHHHHSS?EEEEEEE-TTTTEEEEE???GG---G-?-B???SS?EEEE?TTEEEEEBTEEEEESSSEEE?SEEEEE??S--??B-?T-TS-SSS---BSS 2ZP2|A PF02685.11_Glucokinase_seed 41 388 !Q:5,5|19,27|39,39|41,41|54,56|58,60|63,81|89,92|97,99|105,105|117,117|119,120|138,140|147,147|150,164|168,168|192,192|195,197|203,206|222,223|225,226|231,231|250,255|257,277|287,292|295,296|323,323|326,326|330,331|352,353|359,359|364,365|370,371|373,373|384,384 Q:0,4|6,18|28,38|40,40|42,53|57,57|61,62|82,88|93,96|100,104|106,116|118,118|121,137|141,146|148,149|165,167|169,191|193,194|198,202|207,221|224,224|227,230|232,249|256,256|278,286|293,294|297,322|324,325|327,329|332,351|354,358|360,363|366,369|372,372|374,383|385,387 EEEEE?SSEEEEEEEETTT??-------EEEEEEEEGGG?S?HHHHHHHHHHHH---T???SE-------------------EEEEESS-???SSEE??-SSGGG?EEHHHHHHHTT?S--EEEEEEHHHHHHHHGGG-??GGGEEE?SS??------??-----TTS?EEEEEESSSEEEEEEEEETTEEE-EE???GGGSB????SHHHHHHHHHHHHHS--S??BSTT-TSSHHHHHHHHHHHHHHT------T?????--------------??HHHHHHHHH------TT??HHHHHHHHHHHHHHHHHHHHHHHHHT?TT?EEE??SSGGGGHHHHHTSSHHHHHH??GGGHH-HHTT??EEEE??S?HHHHHHHHHH-HHH 4DB3|A PF02686.10_Glu-tRNAGln_seed 191 117 !Q:0,1|3,4|22,24|27,28|30,31|33,35|37,58|61,71|74,74|76,92|100,100|104,108|112,112 Q:2,2|5,21|25,26|29,29|32,32|36,36|59,60|72,73|75,75|93,99|101,103|109,111|113,116 ??H--HHHHHHHHHHHHHHHHH???TT--S??T---T???????--------?------SS---------??EE?S??-----????--?---HHHHHHT?SSE-----ETT-EEEE 2G5I|C PF02691.10_VacA_seed 2 1002 !Q:0,358|366,379|384,384|398,398|405,405|418,418|420,420|429,432|435,436|449,450|455,455|457,457|460,461|478,478|481,481|483,489|491,506|510,511|536,536|547,549|552,552|555,556|563,563|575,577|581,585|602,602|605,605|629,630|632,632|643,643|646,646|651,651|661,661|667,667|673,673|678,680|692,694|696,696|703,704|715,715|725,725|735,736|740,743|745,746|749,749|767,767|774,775|789,789|795,795|809,809|817,817|826,833|836,838|842,1001 Q:359,365|380,383|385,397|399,404|406,417|419,419|421,428|433,434|437,448|451,454|456,456|458,459|462,477|479,480|482,482|490,490|507,509|512,535|537,546|550,551|553,554|557,562|564,574|578,580|586,601|603,604|606,628|631,631|633,642|644,645|647,650|652,660|662,666|668,672|674,677|681,691|695,695|697,702|705,714|716,724|726,734|737,739|744,744|747,748|750,766|768,773|776,788|790,794|796,808|810,816|818,825|834,835|839,841 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------??EEEEEEE??????????????EEEE?SSEEEEEEEEEEE?SSSSSS?EEEEESSSEEEE?S?EEETTBTT????TT??EEEEEEESTTTS??EEEE?S?EE??TTEEEEEEEEEEEEEE-EE?T-------T?---------------SSE--EEEEEEEEEEEEEEEEEESSEEEE?SSEEEEEEEE???TT?SS??EEEEEE?TTTEEEEEEEE???STT?????EEEEEEEEEEEEEEEE?SS?EEEEEEEEEEEEEEEEEESSTTS??S?EEEEEEEEEE?TT?EEEE?TTEEEEESS?EEEES?EEEEE?BTTB???EEBSSEEEEEE???B?TTTSSB??SEEEETGGGS?SSSEEEEEE?SEEEEEETT?-SSS----S??SS?HHHHHHTTEEEEETTEE?SEEEES--SHHHHHHHHHHHT?HHHHH?GGGGGGGTTEEEE?TTEEEEE?SSEEEEEE??-?????TT???EEE?????----------------------------------------------------------------------------------------------------------------------------------------------------------- 2QV3|A PF02698.12_DUF218_seed 148 299 !Q:0,1|4,4|10,32|35,35|38,38|47,52|56,63|68,74|89,89|96,97|99,99|102,102|108,113|122,131|138,141|143,147|149,151|157,158|163,163|168,168|170,170|173,181|183,186|188,188|190,190|193,194|201,207|210,212|220,223|227,227|232,233|236,238|242,249|259,260|263,265|271,283|290,290|294,297 Q:2,3|5,9|33,34|36,37|39,46|53,55|64,67|75,88|90,95|98,98|100,101|103,107|114,121|132,137|142,142|148,148|152,156|159,162|164,167|169,169|171,172|182,182|187,187|189,189|191,192|195,200|208,209|213,219|224,226|228,231|234,235|239,241|250,258|261,262|266,270|284,289|291,293|298,298 ??SE-EEEES------------------??--?HH-HH-HHHHHHHH------HHT??------EEEE-----??SSTTHHHHHHHHHT?TTGGGS??T-TS?HHHHH------HHHHHHTT?--??-----GGGEEE----E??-??S---HHHHH--HHHH-HHHH-T?SS??-------S---?E-E-EE??TTTHHH-------HH---HHHHHHH?-??TTS?SEEE??SS???EEE--------ETTEEEESS??TT???HHHHH-------------HHHHHH-HHH----H 3CA8|A PF02700.9_PurS_seed 102 87 !Q:2,2|10,12|16,17|32,32|35,35|50,53|56,57|70,70|72,73|82,82|86,86 Q:0,1|3,9|13,15|18,31|33,34|36,49|54,55|58,69|71,71|74,81|83,85 EE-EEEEEEE--?TTS??HHHHHHHHHHHHTT?TT-EEEEEEEEEEEEEE???-SS?-HHHHHHHHHHHT-T??TTTEEEEE-EEE? 2YX5|A PF02702.12_KdpD_seed 21 212 !Q:0,4|33,34|40,42|45,45|56,56|58,60|73,74|80,80|83,84|91,91|94,94|96,97|100,100|117,117|141,144|146,146|148,148|155,155|162,164|176,179|182,183|191,192|210,211 Q:5,32|35,39|43,44|46,55|57,57|61,72|75,79|81,82|85,90|92,93|95,95|98,99|101,116|118,140|145,145|147,147|149,154|156,161|165,175|180,181|184,190|193,209 ?????EEEEEESSTTSSHHHHHHHHHHHHHHTT??EEEEE???TT?HHHHHHHTTS?B???EEEEETTEEEEE??HHHHH-HH??SEEEES?TT?B??TT?SSSBHHHHHHHHHHTT?EEEEEEEGGGBGGGHHHHHHHHS????S?B?HHHHHT?SEEEEB???HHHHHHHHHTT????TT??HHHHHHH??HHHHHHHHHHHHHHHHT?? 2R8R|A PF02706.10_Wzz_seed 38 281 !Q:0,41|50,52|58,60|70,77|82,87|94,94|102,102|113,113|118,123|125,133|136,238|246,250|252,252|263,263|267,267|271,272|275,276 Q:42,49|53,57|61,69|78,81|88,93|95,101|103,112|114,117|124,124|134,135|239,245|251,251|253,262|264,266|268,270|273,274|277,280 ---------------------------------?-------?EEEEEEEE???GGGGH---HHHHHHHHH--------HHTT??????HHHHHH-HHHHHHT?HHHHHHHHHT?HHHH------H?????????SH-------------------------------------------------------------------------------------------------------HHHHHHH-----H-HTTEEEEETT-TSS?TTS??SS??EEEE 3B8M|A PF02709.9_Glyco_transf_7C_seed 98 121 !Q:2,6|15,15|18,18|21,23|40,42|44,46|52,52|65,84|86,91|97,103|107,120 Q:0,1|7,14|16,17|19,20|24,39|43,43|47,51|53,64|85,85|92,96|104,106 EE?--??EEGGGTSS?SS-TT???SEEEEEHHHHHHTTSS?--S???SBSSH-HHHHHHHHHHTT?--?---------------?B?---??TTTTE-------EEE?-?--?-------? 1O0R|A PF02710.9_Hema_HEFG_seed 12 168 !Q:12,12|20,26|29,31|33,33|36,38|40,43|45,45|47,49|60,62|65,71|77,77|85,85|96,99|102,102|108,112|116,116|126,126|134,147|156,156 Q:0,11|13,19|27,28|32,32|34,35|39,39|44,44|46,46|50,59|63,64|72,76|78,84|86,95|100,101|103,107|113,115|117,125|127,133|148,155|157,167 HHHHHHHHHHTT?SEEEEEE?---???SS???E-EE???T----T?S???SSSEEEEESS???EE-------EEEEE?SEETTEE?SEEEEEEEEE---?SS?EEETT-----EEE?EEEEEEETT-EEEEEEE???????--?????EEEEEEEE?SEEEEEEESSS 1FLC|A PF02719.10_Polysacc_synt_2_seed 77 334 !Q:21,24|35,35|46,52|54,55|62,65|67,68|71,71|81,82|84,84|90,95|102,103|127,127|141,142|163,164|169,186|194,196|199,199|215,217|222,222|225,225|229,231|244,245|248,249|252,257|262,265|277,277|283,293|296,297|301,304|307,308|311,311|315,315|322,322|325,325|332,333 Q:0,20|25,34|36,45|53,53|56,61|66,66|69,70|72,80|83,83|85,89|96,101|104,126|128,140|143,162|165,168|187,193|197,198|200,214|218,221|223,224|226,228|232,243|246,247|250,251|258,261|266,276|278,282|294,295|298,300|305,306|309,310|312,314|316,321|323,324|326,331 EEEETTTSHHHHHHHHHHTTT----TBSEEEEEES?HHHHHHHHHH-------H??TTEEEE----E??TT?HHHHHHHTT--T?SEEEE??????HHHHHH-?HHHHHHHHTHHHHHHHHHHHHTT?SEEEEEEEGGGSS??SHHHHHHHHHHHHHHHHHTT?-SSSS-----------------?EEEEEEE???TT?TTSHHHHHHHHHHTT-??EEES?TT?EEE???HHHHHHHHHHHH--HH??TT?-----EEEE??-?EEEHHHHHHHH-HHHTT----------?TT??EEE????TT??SS?EEE?HHHHHH?EE?SSEEEE?? 3VVB|A PF02727.11_Cu_amine_oxidN2_seed 14 96 !Q:0,0|3,6|22,22|24,25|27,27|29,29|38,40|48,52|56,60|62,63|76,77|96,96 Q:1,2|7,21|23,23|26,26|28,28|30,37|41,47|53,55|61,61|64,75|78,95 ?TT????HHHHHHHHHHHHTST-T??T-T?EEEEEEEE???HHHHHHH-----HHH?????S??EEEEEEEETTEE--EEEEEETTTTEEEEEEEE- 2WOH|A PF02728.11_Cu_amine_oxidN3_seed 17 112 !Q:0,3|16,17|19,19|31,32|46,49|54,56|60,60|69,69|74,76|78,78|82,82|84,84|86,87|103,104|107,111 Q:4,15|18,18|20,30|33,45|50,53|57,59|61,68|70,73|77,77|79,81|83,83|85,85|88,102|105,106 ????HHHHHTHHHHHH--T?HHHHHHHHHTT??GGGGGGEEEEEEE????TTTT---TSS?EEEEEEEE?SSTT---S?GGG?B?S-?EEEEETTTTEEEEEE??SS????? 2CFK|A PF02729.16_OTCace_N_seed 105 222 !Q:0,2|5,5|7,7|10,12|14,14|31,38|44,60|65,66|75,76|84,84|93,95|101,103|107,108|110,119|122,130|133,133|145,146|148,149|155,165|175,176|180,185|188,188|190,192|197,200|203,204|216,218 Q:3,4|6,6|8,9|13,13|15,30|39,43|61,64|67,74|77,83|85,92|96,100|104,106|109,109|120,121|131,132|134,144|147,147|150,154|166,174|177,179|186,187|189,189|193,196|201,202|205,215|219,221 ??-BS?G-GG---S?HHHHHHHHHHHHHHHH--------HHHHT-------------????TTTT-?EEEEEESS??HHHHHHH-HHHHHHTT--?EEEEE?--TTT??S----------SS---------SS?HHHHHHHHHHH-?S--EEEEE----------?SSHHHHHHH--HHH?-----SS?E---EEEE?---SS??HHHHHHHHHHH---HHH 3TXX|A PF02730.10_AFOR_N_seed 111 295 !Q:1,1|3,5|22,23|26,26|32,32|43,43|47,49|51,59|62,62|68,68|70,70|76,76|83,83|87,89|95,95|97,101|106,115|123,123|135,135|137,138|145,146|149,149|151,153|159,159|162,169|176,176|181,184|186,188|201,207|209,220|222,226|231,232|239,239|243,243|247,250|253,254|257,263|266,266|269,269|275,275|288,295 Q:0,0|2,2|6,21|24,25|27,31|33,42|44,46|50,50|60,61|63,67|69,69|71,75|77,82|84,86|90,94|96,96|102,105|116,122|124,134|136,136|139,144|147,148|150,150|154,158|160,161|170,175|177,180|185,185|189,200|208,208|221,221|227,230|233,238|240,242|244,246|251,252|255,256|264,265|267,268|270,274|276,287 S?S---EEEEEETTTTEEEEEE??HH-HHHHH?STHHHHHHHH-HHH?-?T---------TS?TTSTT-S?EEEEE?TTTTSS-STT???EEEEE-E?----TTTS----------SEEEEEE?SSHHHHHHHTT?S--EEEEES??SS?E---EEEEE-TT--------EEEEEE?TTTT----T-??HHHHHHHHHHHH-------T----?-------S?---?EEEE??HHHHTT?TTB?EEE----TT--TE-------EE?SS-SHHHH-HHHTTEEEEEEE----???- 1B4N|A PF02732.10_ERCC4_seed 159 318 !Q:1,1|6,22|33,37|40,43|45,54|56,56|61,65|70,94|97,97|100,104|108,108|117,117|120,121|126,130|134,136|138,139|141,143|149,154|159,160|162,172|175,175|178,181|183,183|197,217|221,233|236,260|263,283|294,294|296,298|303,303|306,306 Q:0,0|2,5|23,32|38,39|44,44|55,55|57,60|66,69|95,96|98,99|105,107|109,116|118,119|122,125|131,133|137,137|140,140|144,148|155,158|161,161|173,174|176,177|182,182|184,196|218,220|234,235|261,262|284,293|295,295|299,302|304,305|307,317 E?GGGS??????--------???HHHHTTTTTT--?-?EE????S----------S?SEEE-----EEEE--------------------?????TT?SS?????EEE?SEEEEEEE-HH--HHHH-----HHH---H--T?--HHHHH------HHHH--T-----------SS?SE----E-EEEEETTSSSHHH---------------------HSS------------?HH-------------------------HH---------------------HHHHHHHHHT-T-??EEEE?SS-HHHHHHHHHHH 1J25|A PF02733.12_Dak1_seed 9 366 !Q:7,7|10,10|25,29|31,31|35,35|55,55|70,72|84,86|89,89|116,117|124,125|127,127|129,129|132,132|135,136|140,142|160,164|188,213|221,222|226,228|234,237|245,245|254,255|278,281|284,284|293,293|296,297|313,313|318,318|327,327|330,331|345,345|355,355|361,361|364,365 Q:0,6|8,9|11,24|30,30|32,34|36,54|56,69|73,83|87,88|90,115|118,123|126,126|128,128|130,131|133,134|137,139|143,159|165,187|214,220|223,225|229,233|238,244|246,253|256,277|282,283|285,292|294,295|298,312|314,317|319,326|328,329|332,344|346,354|356,360|362,363 HHHHHHH?TT-EEEETTTTEEEETT?----S?TTS?EEEEEEEESSTTTTGGGBS-BTSBSEEEEEEETS???HHHHHHHHHHH-??SS?EEEEEESSHHHHHHHHHHHHHHHHTT??EEEEEE??B?S?BS?TT?-SSB???THHHHHHHHHHHHHHHT---??HHHHHHHHHHHHTTEEEEEEEEE?????????????-----------??TTEEEET??TTS???SEEEE???-HHHHHHH-HHHHHHHS??EEEEEEEEETTTTEEEEEEEEE????TT?EEEEEEEE?BS??HHHHHHHHHHHHHHH-HHHT?EEEEEEEE?SS??TTBEEEEEEEEEE?HHHHHHHHS?EESSS?EE?? 3CT4|A PF02734.12_Dak2_seed 175 222 !Q:5,5|25,31|35,35|52,52|71,76|78,79|82,89|91,93|97,97|107,107|114,114|116,124|144,144|148,152|155,156|169,169|180,183|196,196|198,203|205,206 Q:0,4|6,24|32,34|36,51|53,70|77,77|80,81|90,90|94,96|98,106|108,113|115,115|125,143|145,147|153,154|157,168|170,179|184,195|197,197|204,204|207,221 HTSSS?HHHHHHHHHHHHHHTHHHH-------TTS?HHHHHHHHHHHHHHHT?TTHHHHHHHHHHHHHTTS-----?S-?SE--------E--?HHH-HHHHHHHHH-HHHHHH-H------???TTSSSTHHHHHHHHHHHHH-HHH-----TT??HHHHHHHHHHHH-HHHHHTTTTS?-??SSGGGGGGGGGT-T------S??HHHHHHHHHHHHHHH 2BTD|A PF02735.11_Ku_seed 29 315 !Q:4,7|10,10|17,18|20,20|23,32|37,43|45,46|60,90|92,96|105,110|112,112|115,115|120,120|129,130|132,139|152,152|155,155|158,160|162,163|169,169|174,174|186,187|203,203|206,206|208,210|219,220|223,223|225,259|261,264|268,271|279,281|286,307 Q:0,3|8,9|11,16|19,19|21,22|33,36|44,44|47,59|91,91|97,104|111,111|113,114|116,119|121,128|131,131|140,151|153,154|156,157|161,161|164,168|170,173|175,185|188,202|204,205|207,207|211,218|221,222|224,224|260,260|265,267|272,278|282,285|308,314 EESS----SS?EEEEEE--E?SB??????????EETT-------T??BEEEEEEEEETTT??-----------------------------B??---GGGEEEEE------E?SS?EEEE?HHHHHHTT??S?-------SEEEEEEEEEGG-GS?TT???S??EEEEE?TTTE-ETHHHHHHHHH--HHHHHHTEEEEEEEE?SS-S???EEEEEEEE??EE?T-----------------------------------T?--?EEE?---SEEEEEE???GGGB?-??????????---------?HHHHHHH 1JEQ|A PF02736.14_Myosin_N_seed 41 52 !Q:6,6|8,8|12,13|21,26|29,29|37,38|40,43|48,48 Q:0,5|7,7|9,11|14,20|27,28|30,36|39,39|44,47|49,51 TTEEEE-E?STT--SEEEEEE?--???SS?EEEEEST--T??--EEEE?GGG 1BR1|A PF02737.13_3HCDH_N_seed 74 211 !Q:0,0|5,7|22,22|24,25|30,30|32,38|52,54|66,74|87,88|91,92|98,98|100,101|107,111|127,128|131,131|136,137|141,141|151,151|156,157|164,165|167,167|172,173|180,180|183,184|199,199|201,201|207,207|210,210 Q:1,4|8,21|23,23|26,29|31,31|39,51|55,65|75,86|89,90|93,97|99,99|102,106|112,126|129,130|132,135|138,140|142,150|152,155|158,163|166,166|168,171|174,179|181,182|185,198|200,200|202,206|208,209 ?EEEE??-SHHHHHHHHHHHHT-T??EEEE?S------?HHHHHHHHHHHHH---HHHTTTTTTSS?--------HHHHHHHHHTEE--EE??GGGGG-G?-SEEEE?????HHHHHHHHHHHHHHS-?TT?EEEE??SSS?HHHHTTTSS-SGGG--EEEEEE?-S-STTT??EEEEEE?SS??HHHHHHHHHHHHHT-T?EEEEE-ES? 3ZW8|A PF02738.13_Ald_Xan_dh_C2_seed 30 654 !Q:3,8|11,12|16,29|36,40|47,47|50,72|81,82|84,87|90,91|97,99|103,103|109,110|112,112|126,127|136,138|140,141|166,166|171,172|181,183|185,186|196,196|200,200|216,216|231,233|238,239|251,251|254,260|262,262|285,287|297,301|304,304|306,306|309,311|313,314|316,317|321,323|339,345|351,355|360,361|379,379|385,385|394,394|398,401|408,410|428,436|439,439|446,447|450,450|455,455|457,459|461,461|493,502|505,505|510,517|526,528|536,548|550,550|557,559|561,561|565,566|598,598|601,601|603,603|625,628|630,631|635,635|637,639|645,648|653,653 Q:0,2|9,10|13,15|30,35|41,46|48,49|73,80|83,83|88,89|92,96|100,102|104,108|111,111|113,125|128,135|139,139|142,165|167,170|173,180|184,184|187,195|197,199|201,215|217,230|234,237|240,250|252,253|261,261|263,284|288,296|302,303|305,305|307,308|312,312|315,315|318,320|324,338|346,350|356,359|362,378|380,384|386,393|395,397|402,407|411,427|437,438|440,445|448,449|451,454|456,456|460,460|462,492|503,504|506,509|518,525|529,535|549,549|551,556|560,560|562,564|567,597|599,600|602,602|604,624|629,629|632,634|636,636|640,644|649,652 TTT------TT??SSS-------------?EEEEES?---?SHHHHT?SE-----------------------EEEEEEEE??B????SS??EEEEE???STT?EEEEE??S?HHHHHHHHHHHHT??GGGEEEEE???S??TTTTTSTHHHHHHHHHHHHHHHSS?EEEE??HHHHHHHT-??B??EEEEEEEEE?SSS?EEEEEEEEEEEEESS?TTHHHHHHHHHTTT---TTTB??SSEEEEEEEEE?SS????-??T-TTTSSSSBTTBTTHHHHHHHHH???HHHHHHHTB?---?TT?B?TT-??B??S??HHH---HHHHHHHHTTHHHHH-------HHHHH-----HHHH?-SSEEEEEEEEEEEEEES?SSGGG?EEEEEEEE?TTS?---EEEEES???SSSSHHHHHHHHHHHHH---------TS?GGGEEE??EE-TTTS?S???S?SSTHHHHHHHHHHHHHHHHHHHHHHHHHTST----------TS?HHHH--------HHHHHHHT???EEEEEEE??-----------S?EEETTT---T-EEE??SEEEEEEEEEEEEEETTTTEEEEEEEEEEEE?BS?S?TTHHHHHHHHHHHHHHHHHHT????B?-TTS?B???STTTS????GGGS? 1DGJ|A PF02739.11_5_3_exonuc_N_seed 25 197 !Q:0,0|20,24|26,26|34,34|36,36|52,54|61,95|98,98|117,117|121,122|126,126|142,143|145,145|151,153|160,161|163,165|171,171|173,181|184,184|187,187|195,195|197,197 Q:1,19|25,25|27,33|35,35|37,51|55,60|96,97|99,116|118,120|123,125|127,141|144,144|146,150|154,159|162,162|166,170|172,172|182,183|185,186|188,194|196,196 ?EEEEEEHHHHHHHHHTSST-----T?EETTEEE?H-HHHHHHHHHHHHHHH??-SEEEEE??????--??????????????------------?SS?SSHHHHHHHHHHHHHHTT?EEE??TTS?HHHHHHHHHHHHHHT--T?EEEEE???GGGGGT??S---SEEEE?S---------SS?EE?HHHHHHH-T- 1XO1|A PF02740.9_Colipase_C_seed 5 45 !Q:5,5|7,9|12,12|16,17|19,19|22,22|29,30|35,35|38,38|45,45 Q:0,4|6,6|10,11|13,15|18,18|20,21|23,28|31,34|36,37|39,44 TTSEE?S???SS?BSS??B?TT?EEEEEE??TTSS?SS?EEEEET- 1PCO|A PF02741.10_FTR_C_seed 38 162 !Q:8,8|13,13|50,51|56,56|60,61|65,65|67,68|70,71|74,75|77,77|79,80|84,84|91,92|95,98|101,102|130,134|144,147|152,152 Q:0,7|9,12|14,49|52,55|57,59|62,64|66,66|69,69|72,73|76,76|78,78|81,83|85,90|93,94|99,100|103,129|135,143|148,151|153,161 TEEEEEES?EEEE-EEEEEEEEEEEESSHHHHHHHHHHHHHHHTTSTTEE??SGGG?BSS??BSS?S--S?-TT-?S?B??GGG?GGGGGG-?TT????TT??EEEEEEEEESSHHHHHHHHHHHHHHHT-----TSTTEEEEE????TTSS?SEEEEGGGG 2FHJ|A PF02742.10_Fe_dep_repr_C_seed 141 75 !Q:0,0|26,29|44,45|57,58|61,62|64,64|68,68|70,73 Q:1,25|30,43|46,56|59,60|63,63|65,67|69,69|74,74 ?HHHHHHHHHHHHHHHHHHHHHHHTT??-?HHHHHHHHHHHTTT??HHHHHHHHHHT--TS??B?TTS?B?-??H 1DDN|A PF02743.13_Cache_1_seed 19 103 !Q:1,3|6,6|9,19|21,22|33,43|47,48|58,58|68,68|70,71|89,89 Q:0,0|4,5|7,8|20,20|23,32|44,46|49,57|59,67|69,69|72,88|90,102 E???EE?TT-----------T??EEEEEEEEEE?----------TTT??EEEEEEEEE?HHHHHHHHT?S??TTSEEEEEEETTSBEEE?SSGGGTTSBTHHH 3C8C|A PF02744.12_GalP_UDP_tr_C_seed 9 233 !Q:1,8|20,27|30,30|38,44|50,50|57,57|60,60|65,66|69,70|74,74|80,80|83,84|90,91|94,103|111,118|133,141|143,145|152,154|159,163|166,168|174,175|177,177|182,182|184,188|195,196|201,201|211,220|223,224|227,227|232,232 Q:0,0|9,19|28,29|31,37|45,49|51,56|58,59|61,64|67,68|71,73|75,79|81,82|85,89|92,93|104,110|119,132|142,142|146,151|155,158|164,165|169,173|176,176|178,181|183,183|189,194|197,200|202,210|221,222|225,226|228,231 H--------HHHHHHHHHHH--------SS?HHHHHHH-------HHHHH?TTEEEE?SS-EEEE??TT??STT?EEEEE-SS??SSGGG??HH----------HHHHHHH--------HHHHHHHHHHHHHT---------S???EEEEEE???SSSS??---TT???EEEEE??B?SSSS?B????-THHHHT??EESS?HHHHHHHHH----------TS?-SS?HHHH? 1GUP|A PF02745.10_MCR_alpha_N_seed 5 271 !Q:0,4|12,12|14,14|16,16|19,20|22,24|26,26|28,28|33,33|51,52|54,57|61,62|64,65|67,67|70,72|80,81|93,93|111,111|123,127|145,146|149,149|152,156|160,160|163,163|171,171|179,179|184,185|191,191|203,203|205,205|212,213|221,221|243,244|247,247|266,268|270,270 Q:5,11|13,13|15,15|17,18|21,21|25,25|27,27|29,32|34,50|53,53|58,60|63,63|66,66|68,69|73,79|82,92|94,110|112,122|128,144|147,148|150,151|157,159|161,162|164,170|172,178|180,183|186,190|192,202|204,204|206,211|214,220|222,242|245,246|248,265|269,269 ?????HHHHHHH?S-S?TT??B???S?S?GGGG?HHHHHHHHHHHHHHHHH?-S????TTS--S??S?SS???EEEBTTS??EEEGGGSSGGG?HHHHHHHHHHHTEEEEE?HHHHHHHHHTT?????HHHHHHHHHHHHHHTTT??SS?TT?????TTT?TT?EEEEEES?HHHHTTS?GGGB??HHHHS?HHHHHHHHHHH?S?EEEEEE??HHHHHHS?HHHHHHHHHHHHHHHHHHHHT??SS?TTHHHHHHHHHTTSEEES???B? 1HBN|A PF02746.11_MR_MLE_N_seed 9 129 !Q:13,14|35,35|46,47|56,57|80,80|92,92|95,100|121,121 Q:0,12|15,34|36,45|48,55|58,79|81,91|93,94|101,120|122,128 EEEEEEEEEEEEE--EEEETTEEEEEEEEEEEEEE-ETTEEEEEEE??STTTTTSS??HHHHHHHHHHTHHHHHTTSBTT?HHHHHHHHHHH?SS-----?HHHHHHHHHHHHHHHHHHTT?BHHHHHT 4HCH|A PF02747.10_PCNA_C_seed 12 128 !Q:0,6|28,28|36,36|39,39|46,46|49,49|56,62|65,69|71,72|75,76|95,95|113,114|125,127 Q:7,27|29,35|37,38|40,45|47,48|50,55|63,64|70,70|73,74|77,94|96,112|115,124 ???????SEEEEEEHHHHHHHHHHHHTT?SEEEEEE?SS?EEEEEE?SS?EEEEEE???????SS?????B??SS??EEEEEHHHHHHHGGGTTT?SEEEEEEETTEEEEEEE??TTTEEEEEEE??? 3F1W|A PF02748.10_PyrI_C_seed 70 58 !Q:3,3|6,7|9,10|12,12|15,15|19,20|22,22|25,28|36,36|47,48|57,57 Q:0,2|4,5|8,8|11,11|13,14|16,18|21,21|23,24|29,35|37,46|49,56 SEE?SS--S??S?TT?TTS--S-SS????EEEEEET-TEEEEEETTT??EEEHHHHH? 2YWW|A PF02749.11_QRPTase_N_seed 161 130 !Q:2,4|6,8|12,12|17,17|20,20|24,26|34,35|38,41|48,48|54,72|75,76|80,81|85,85|88,88|91,91|94,102 Q:0,1|5,5|9,11|13,16|18,19|21,23|27,33|36,37|42,47|49,53|73,74|77,79|82,84|86,87|89,90|92,93|103,129 HT---T?-?HHH-HHHS?TT?EEE---EEEEESS?-EE??-?HHHHHH-HHHHH------------------?TT?-EEE--ESS?TT?EE?TT?--------EEEEEEEEHHHHHHHHHHHHHHHHHHH 3C2O|A PF02750.9_Synapsin_C_seed 4 203 !Q:1,1|10,10|26,26|31,31|33,35|47,49|59,60|69,69|87,87|93,95|119,119|122,122|134,136|152,153|167,167|175,175|178,181|184,184 Q:0,0|2,9|11,25|27,30|32,32|36,46|50,58|61,68|70,86|88,92|96,118|120,121|123,133|137,151|154,166|168,174|176,177|182,183|185,202 S?HHHHHHTT?HHHHHHHHHHHHHHH?TTTS?B???EEESSGGGGGS???SSEEEEESS??TTTTEEEE?STTHHHHHHHHHHHHTS?EEEEE???EEEEEEEEEETTEEEEEEEEESS?SS?TTSSSEEEEEE???HHHHHHHHHHTTGGG??SEEEEEEEEETTS?EEEEEEE?TT????SS?HHHHHHHHHHHHHHHHHH 1PK8|A PF02751.9_TFIIA_gamma_C_seed 26 75 !Q:1,3|8,10|12,12|38,59 Q:0,0|4,7|11,11|13,37|60,74 S???EEEE---E-EEEEEEEEETTEEEEEEEEEEEEEE??????-------?????????EEEEEEEEEEEEEES 1NH2|D PF02752.17_Arrestin_C_seed 173 416 !Q:0,2|12,12|19,20|29,35|37,38|41,52|67,67|70,141|143,143|145,145|154,155|159,197|199,199|204,204|212,233|236,273|278,278|284,285|287,296|298,346|348,349|354,354|369,384|387,396|406,407|409,415 Q:3,11|13,18|21,28|36,36|39,40|53,66|68,69|142,142|144,144|146,153|156,158|198,198|200,203|205,211|234,235|274,277|279,283|286,286|297,297|347,347|350,353|355,368|385,386|397,405|408,408 ???EEEEEEEES?SEEETT??EEEEEEEE-------E-?SS-??---------EEEEEEEEEEEEEE?SS------------------------------------------------------------------------S?E-EEEEEEEE--EEE???------------------------------------B?TTEE-EEEEEEE------------??????????TT-------------------------------------?EESS?TTSTT??B??---?????T-------------------------------------------------T??SSTT?EEEEEEEEEEEEET----------------TS?--------?EEEEEEEEE--E??---?? 1G4R|A PF02753.12_PapD_C_seed 155 95 !Q:4,5|9,9|11,11|16,16|20,30|34,34|37,44|46,46|49,49|55,68|75,75|79,87|90,92|95,95 Q:0,3|6,8|10,10|12,15|17,19|31,33|35,36|45,45|47,48|50,54|69,74|76,78|88,89|93,94 EEEE??SSS?B?EEEE-EET-----------TEE?SS??-----?B?TT?EEEEE???????------?EEEEEB?TTS---------SB???EE- 3DOS|A PF02755.10_RPEL_seed 54 26 !Q:9,11|22,23|25,25 Q:0,8|12,21|24,24 HHHHHHHHH???HHHHHTTTSS??S? 4B1Z|M PF02758.11_PYRIN_seed 38 94 !Q:1,2|12,12|25,31|39,43|50,53|83,83|85,85 Q:0,0|3,11|13,24|32,38|44,49|54,82|84,84|86,93 T??HHHHHHTTS?HHHHHHHHHHHH-------HHHHHTT?????HHHHHH-??-HHHHHHHHHHHHHHHHHHHHHHHHHHHTT?H-HHHHHHHH 4EWI|A PF02759.14_RUN_seed 50 366 !Q:14,127|130,133|143,159|163,164|171,173|179,179|181,181|184,185|188,245|249,270|283,283|297,299|302,314|316,323|327,327|330,330|339,344|356,365 Q:0,13|128,129|134,142|160,162|165,170|174,178|180,180|182,183|186,187|246,248|271,282|284,296|300,301|315,315|324,326|328,329|331,338|345,355 HHHHHHHHHHTTTB??-----------------------------------------------------------------------------------------------------------?--??TT????TTHHHHHTG-----------------GGT-?TTHHHH---HHHTT-T?TT??SH----------------------------------------------------------HHH----------------------HHHHHHHHHHTT?HHHHHHHHHTTTT---TH-------------H--------HHB?SS?STTSHHHH------HHHHHGGGGTT-????????? 3CWZ|B PF02760.10_HIN_seed 10 170 !Q:1,1|3,3|12,14|19,23|34,34|37,37|44,45|73,73|76,76|81,82|86,90|99,102|110,110|113,113|127,127|153,156|159,159 Q:0,0|2,2|4,11|15,18|24,33|35,36|38,43|46,72|74,75|77,80|83,85|91,98|103,109|111,112|114,126|128,152|157,158|160,169 B?S?EEEEEEEE???EEEE?????EEEEEEEEEE?SS?EEEEEE??GGGGGGGSSSSEEEEESBEEETTEEEE?TT?EEEE??GGG?????HHHHHHHT????HHHHTTS?TT?EEEEEEEEEEEEE?SSEEEEEEEETTEEEEEEEEGGGSS????TT?EEEEEEEEEE 3RN2|A PF02761.9_Cbl_N2_seed 5 86 !Q:1,3|19,19|36,38|41,41|52,52|55,55|72,73 Q:0,0|4,18|20,35|39,40|42,51|53,54|56,71|74,85 T???SSHHHHHHHHHHHTT?SEEEHHHHHHHHHTTS???TT-HHHHHHHHHH?TT?SSEEEHHHHHHHHHHT??GGGHHHHHHHHT 3OP0|A PF02762.9_Cbl_N3_seed 4 86 !Q:1,1|5,5|8,9|32,32|45,45|49,49|54,56|59,59|74,74|79,79|81,85 Q:0,0|2,4|6,7|10,31|33,44|46,48|50,53|57,58|60,73|75,78|80,80 S?TTB?TT??HHHHHHHHGGGTTSTTEEEEEE?SSSTTSEEEEEE?TTS?EEEE???SS?HHHHHHHHHHTTSS?EETT?S????? 3OP0|A PF02763.9_Diphtheria_C_seed 3 187 !Q:0,0|6,6|10,10|16,16|23,23|26,26|33,37|41,41|44,44|50,50|57,57|65,65|67,67|75,75|77,77|84,84|95,97|107,108|112,112|130,130|139,140|143,145|151,151|158,158|170,171|186,186 Q:1,5|7,9|11,15|17,22|24,25|27,32|38,40|42,43|45,49|51,56|58,64|66,66|68,74|76,76|78,83|85,94|98,106|109,111|113,129|131,138|141,142|146,150|152,157|159,169|172,185 ?HHHHB?GGG?EEEET?EEEEEE?TT?TTGGGG?????SSS?TT?SSGGG?SEEEES?HHHHHTT?B?TTSTTTS?B?EEEEEE?SSEEEEEEBS???HHHHHHHTT??TTS?HHHHHTSHHHHHHHSTT?SEEEEEEE??TT???EEEEE?TTGGGG?EEEEEEEGGGG??STTHHHHHHHHGGG? 1F0L|A PF02764.9_Diphtheria_T_seed 3 180 !Q:0,5|23,23|34,35|37,39|70,70|74,74|89,90|96,96|107,107|109,109|122,124|148,154|178,179 Q:6,22|24,33|36,36|40,69|71,73|75,88|91,95|97,106|108,108|110,121|125,147|155,177 ??????HHHHHHHHHHHHHHHHT?HHHHHHHHTS??S???HHHHHHHHHHHHHHHTTSGGGHHHHHHHTT?GGG?HHHHHHHHHHHHHH??HHHHT?HHHHHHHHTT?S?HHHHHTEETTEE???SHHHHHHHHHHHHHHHHHHHHHH???????TTTTHHHHHHHHHHHHHHHHHTS?? 1F0L|A PF02765.12_POT1_seed 48 309 !Q:1,2|9,9|12,12|25,25|35,35|40,41|52,52|55,56|59,59|69,69|72,73|76,76|90,114|117,117|128,131|143,143|146,146|149,149|153,153|160,160|162,163|174,174|180,180|213,215|219,219|223,223|235,235|251,251|261,276|278,278|280,283|285,286|289,289|297,305 Q:0,0|3,8|10,11|13,24|26,34|36,39|42,51|53,54|57,58|60,68|70,71|74,75|77,89|115,116|118,127|132,142|144,145|147,148|150,152|154,159|161,161|164,173|175,179|181,212|216,218|220,222|224,234|236,250|252,260|277,277|279,279|284,284|287,288|290,296|306,308 S??GGGGGG?SS?EEEEEEEEEEEE?SSSEEEEEE-EETT??EEEEEEETTT?TT??TT?EEEEEEEEE?TT??SS?EEEEEEEEEEEEE?------------------------TT?HHHHHHHHHS????HHHHHHTTSSS?SS?EE?EEE?GGGTTS?B??HHHHHHTTTT?HHHHT?SEEEEEEEEEEEESSSGGGSEEEEETTTTEEE?--GGG?STT?EEEEEEEEEEE?GGGSSBSEEEEEEEE?TTSTTTTTT----------------S-S????T--TT?HHHHHHH---------HHH 1K8G|A PF02767.11_DNA_pol3_beta_2_seed 15 130 !Q:2,2|18,18|21,21|37,40|48,48|65,66|84,85|87,88|91,92|99,105|122,122|124,124|126,129 Q:0,1|3,17|19,20|22,36|41,47|49,64|67,83|86,86|89,90|93,98|106,121|123,123|125,125 EE?HHHHHHHHHTTGGGS?SS?SSGGGSEEEEEEEEE----EEEEEEE?SSEEEEEEEEEEEEEE--EEEEEEEHHHHHHHHHT??S--SS??EEEEEE-------SSEEEEEETTEEEEEE?B?S???? 3BEP|A PF02768.10_DNA_pol3_beta_3_seed 16 128 !Q:4,4|6,8|30,31|35,35|43,44|54,54|57,58|63,64|68,68|70,73|75,76|94,94|103,104|108,108|124,125|127,127 Q:0,3|5,5|9,29|32,34|36,42|45,53|55,56|59,62|65,67|69,69|74,74|77,93|95,102|105,107|109,123|126,126 HHHS?S???EEEEEEHHHHHHHHHHHHTTS?-TTT?EEEEEEE--TTEEEEEEE?TT??EEEE--EEE?B??--S??EEEEEEHHHHHHHHHHH?SSEEEEEE??TTS?EEEEETTEEEEEEEE??B? 3BEP|A PF02769.17_AIRS_C_seed 169 252 !Q:0,0|3,3|10,18|38,39|44,47|51,51|61,66|75,76|80,82|87,88|101,101|104,105|114,132|135,137|147,150|153,154|162,197|207,207|211,213|223,224|228,233|243,249 Q:1,2|4,9|19,37|40,43|48,50|52,60|67,74|77,79|83,86|89,100|102,103|106,113|133,134|138,146|151,152|155,161|198,206|208,210|214,222|225,227|234,242|250,251 ?TT?EEEEEE?--------SSSTTSSHHHHHHHHHHSS??TTSB??--TTS?SSBHHHHHT??????HHHHHHHH--HTT???EEEE??TTHHHHHSGGGS?TT--EEEEEEGG-------------------GS???HHHHHHHHH----HT??HHHHHHH----------------------------------??TTEEEEEEE?GGG---HHHHHHHHH--HTT?----?EEEEEEEEE???????EE 3C9R|A PF02770.14_Acyl-CoA_dh_M_seed 69 81 !Q:3,4|8,8|12,12|14,21|24,26|35,41|46,50|59,59|61,62|65,69|79,79 Q:0,2|5,7|9,11|13,13|22,23|27,34|42,45|51,58|60,60|63,64|70,78|80,80 EEE??BTT-BSS?G--------GG???EEEEETTE-------EEEE-----EEEEEEET-G--GG?----SEEEEEEEE-T 1UKW|A PF02771.11_Acyl-CoA_dh_N_seed 988 235 !Q:0,1|3,9|13,14|20,22|26,26|31,32|35,35|37,38|40,44|46,53|58,62|64,65|67,70|73,73|75,88|91,92|94,95|100,100|102,102|104,104|106,106|108,108|114,120|125,152|166,167|169,172|174,177|182,182|187,188|194,194|196,199|201,202|205,208|212,214|220,222|224,225 Q:2,2|10,12|15,19|23,25|27,30|33,34|36,36|39,39|45,45|54,57|63,63|66,66|71,72|74,74|89,90|93,93|96,99|101,101|103,103|105,105|107,107|109,113|121,124|153,165|168,168|173,173|178,181|183,186|189,193|195,195|200,200|203,204|209,211|215,219|223,223|226,234 ?-H-------HHH--HHHHH---HHH-HHHH--TT-H--H-----H--------HHHH-----H--H----HT-S---------??---TH--H--HHHH-H-H-T-T?TTTTS?------GGGT-?---?-?--?-------------?---HHHHHHHHHHHHH--H?---H----HHHH-HHHH--HHTTT-H----H--HH----HHH??-HHHHH---H--HHHHHHHTS 1UKW|A PF02772.11_S-AdoMet_synt_M_seed 192 191 !Q:1,3|5,7|10,10|26,26|44,45|47,48|51,51|53,55|57,66|82,83|85,85|87,95|97,101|103,107|110,110|115,115|122,123|127,143|161,162|164,165|167,170|172,174|176,177|179,180|188,190 Q:0,0|4,4|8,9|11,25|27,43|46,46|49,50|52,52|56,56|67,81|84,84|86,86|96,96|102,102|108,109|111,114|116,121|124,126|144,160|163,163|166,166|171,171|175,175|178,178|181,187 G---G???SS?EEEEEEEETTSTTSS?HHHHHHHHHHHHHHHHH--H--TS-S---S----------TTEEEEEEEEEEEEE--S-S---------S--?--E-----EE-EEEE-EEEEEE-?SSS?----------------HHHHHHHHHHHTTTTTS-?G--G----G-??T--T-?EEEESTT??? 1MXA|A PF02773.11_S-AdoMet_synt_C_seed 11 145 !Q:1,1|7,7|13,13|24,26|28,30|34,34|37,37|59,59|69,69|72,73|75,75|82,82|85,86|88,89|91,91|103,106|120,123|131,131|138,140|145,145 Q:0,0|2,6|8,12|14,23|27,27|31,33|35,36|38,58|60,68|70,71|74,74|76,81|83,84|87,87|90,90|92,102|107,119|124,130|132,137|141,144 S?GGGTS?EETTS?TTTTTTTTSS???S???TTB?TT?HHHHHHHHHHHHHHHHHHTTS?SEEEEEEEE?BT??S?SEEEEE?TT??S--S?HHHHHHHHHHH????HHHHHHHHTTTSS---?GGGGSSS?SSSSTT--?GGGS- 1MXA|A PF02774.13_Semialdhyde_dhC_seed 32 238 !Q:6,7|10,10|12,12|22,22|27,27|55,55|73,74|80,81|85,85|88,89|91,91|93,93|97,98|116,116|119,126|134,134|136,136|150,154|156,158|170,178|184,185|187,187|203,206|208,208|217,217|220,220|223,224 Q:0,5|8,9|11,11|13,21|23,26|28,54|56,72|75,79|82,84|86,87|90,90|92,92|94,96|99,115|117,118|127,133|135,135|137,149|155,155|159,169|179,183|186,186|188,202|207,207|209,216|218,219|221,222|225,237 SHHHHT--TT?E-EEEEEEEEE?GGGG?HHHHHHHHHHHHHHHHTTHHHHHSTTS?HHHHHHHHHHHHHSTTS??TTTSS??TTS?BS??S?B?SSS--SBHHHHHHHHHHHHHHT?SS-----???EEEEEEE?S?SSEEEEEEEEEES-----S???HHHHHHHHHTT--------?TTEEE??S?HHHHHHHSSHHHHTT---?S?EEEEEEEE?TT?TT--EEEEEEEEETTTT 1GL3|A PF02775.16_TPP_enzyme_C_seed 327 232 !Q:0,0|7,7|13,15|17,19|21,21|24,25|28,36|39,40|43,43|53,54|56,59|61,68|70,71|73,77|79,79|83,83|91,92|97,97|99,99|109,110|112,115|122,123|126,126|133,135|138,138|144,146|148,169|177,177|179,180|184,184|187,189|191,191|193,194|196,197|201,203|211,213|215,220|222,222|225,225|229,229 Q:1,6|8,12|16,16|20,20|22,23|26,27|37,38|41,42|44,52|55,55|60,60|69,69|72,72|78,78|80,82|84,90|93,96|98,98|100,108|111,111|116,121|124,125|127,132|136,137|139,143|147,147|170,176|178,178|181,183|185,186|190,190|192,192|195,195|198,200|204,210|214,214|221,221|223,224|226,228|230,231 ?SSHHHH-HHHHH---S???S-TT?-EE?---??---SS??TT?HHHHHHHHH--H----H------?-T--T-----S-EEE-EEEEHHH--HHHH-G-GGHHHHHHH--T?-??EEEEEE?-SS?HHHHHH---HH-HHSTT???S??---------------?????HHHHHHH-T--TSE-EE---E-E??G--GGH---HHHHHHH---H------H?SS?EEE-EE 1PVD|A PF02776.13_TPP_enzyme_N_seed 118 238 !Q:0,0|13,13|16,17|19,33|37,39|45,45|53,53|55,60|62,62|66,67|79,80|85,86|89,89|92,99|105,105|107,107|110,110|126,126|128,129|137,138|144,152|155,155|158,164|169,173|176,177|181,181|184,189|193,194|211,212|217,218|233,234|236,236 Q:1,12|14,15|18,18|34,36|40,44|46,52|54,54|61,61|63,65|68,78|81,84|87,88|90,91|100,104|106,106|108,109|111,125|127,127|130,136|139,143|153,154|156,157|165,168|174,175|178,180|182,183|190,192|195,210|213,216|219,232|235,235|237,237 ?BHHHHHHHHHHH-TT??E---------------EEE???STTHH-HHHHHTT?S------S?EEE??SSHHHHHHHHH--HHHH--HH-SS-------?EEEEE?S-TH-HHHTTHHHHHHHHHH-T??EEEEEEE??TTTTT---------TT?TT-??--?-HHHH-----TG--GGS-SE------EEE??SGGGHHHHHHHHHHHH--HSSS??EEEEEEEHHHHHSB??S?B 1PVD|A PF02777.13_Sod_Fe_C_seed 27 116 !Q:1,8|36,37|48,50|63,64|66,66|71,73|81,81|93,93|103,103|107,107 Q:0,0|9,35|38,47|51,62|65,65|67,70|74,80|82,92|94,102|104,106|108,115 S-?-??---HHHHHHHHHHHSSHHHHHHHHHHHHHH??SSEEEEEEEE---TTEEEEEEEETT??G-GGGT--?EEEEEEE?SGGGTHHHHTT?HHHHHHHHT-TTB?HHHHHHHH 1SZX|A PF02778.9_tRNA_int_endo_N_seed 65 92 !Q:0,0|5,5|12,18|25,27|33,34|40,41|43,44|51,52|54,54|69,69|72,72|76,79|83,83|86,86 Q:1,4|6,11|19,24|28,32|35,39|42,42|45,50|53,53|55,68|70,71|73,75|80,82|84,85|87,91 ?EEEE?SSEEEE?-----?HHHHHH---HHHTT??SEETT??S??GGGGGG??S?EEEEHHHHHHHHHT-TS?EEE---?TTS?EE?HHHHH 3P1Z|B PF02779.19_Transket_pyr_seed 93 245 !Q:1,1|3,3|20,21|31,46|48,48|52,55|59,59|64,64|67,67|70,73|75,75|77,77|80,82|87,89|91,91|106,106|115,117|125,126|142,148|154,156|160,160|165,167|175,176|178,199|201,202|206,208|224,226|228,231|237,237|243,243|245,245 Q:0,0|2,2|4,19|22,30|47,47|49,51|56,58|60,63|65,66|68,69|74,74|76,76|78,79|83,86|90,90|92,105|107,114|118,124|127,141|149,153|157,159|161,164|168,174|177,177|200,200|203,205|209,223|227,227|232,236|238,242|244,244 S?B?HHHHHHHHHHHHHTTT??EEEEETTTT----------------T?TTS????SEE?SSSS?EE?GG----G?S?TT???EEEE???S?HHHHHHHHHHHHHH?TTSEEEEE???GGGGGGG--HHHHHHTTTTHHHHH?????-?EEEEE???SSS?TTSS???HHHHHHT??T----------------------T??EEE???SHHHHHHHHHHHHHS---S????EEEEE?SGGGG?T- 2BEU|B PF02780.15_Transketolase_C_seed 80 146 !Q:1,2|6,8|10,11|19,19|37,41|43,44|50,50|56,57|62,64|70,71|75,75|78,79|87,87|102,102|108,108|111,112|118,120|124,129|138,139|142,142|146,146 Q:0,0|3,5|9,9|12,18|20,36|42,42|45,49|51,55|58,61|65,69|72,74|76,77|80,86|88,101|103,107|109,110|113,117|121,123|130,137|140,141|143,145 T??EEE---E??SSEEEEE?TTHHHHHHHHHHHHHTT-----T??EEEEE?SEEES??HHHH---HHHHH--HHS?EE--EEEEEET-TSSSHHHHHHHHHH-HSTTS?SS??EEEEE--?SSS???---GGGHHHHS??HH-HHH- 2BEU|B PF02781.11_G6PD_C_seed 11 308 !Q:6,6|13,13|27,27|29,31|34,34|61,64|84,87|92,95|102,103|107,107|111,111|114,114|118,118|122,122|125,128|138,138|145,145|155,155|158,158|167,169|172,173|177,184|194,194|204,204|208,212|228,228|232,235|248,249|253,254|274,274|277,280|290,290|302,305|307,307 Q:0,5|7,12|14,26|28,28|32,33|35,60|65,83|88,91|96,101|104,106|108,110|112,113|115,117|119,121|123,124|129,137|139,144|146,154|156,157|159,166|170,171|174,176|185,193|195,203|205,207|213,227|229,231|236,247|250,252|255,273|275,276|281,289|291,301|306,306 HHHHHS?GGGSTT?STTTEEEEEEEEE?S???TT?HHHHTTTHHHHHTTTTHHHHHHHHHH????SSSSHHHHHHHHHHHHTTB????GGGE----EEEEEE??TTS?STT-SS?GGG?TTS?TT????SEEEEEEEB?STTTTT?EEEEEEESS?SS?EEEEEEEE???SS??STT?---????EEEEEEESS?EEEEEEEEE?TTT?---?SEEEEEEEEETTTSS-SSS????HHHHHHHHHHHT??TTS??HHHHHHHHHHHHHHHHHHH-HH????EEEETTSSS?HHHHHHHHHHT????S? 2BH9|A PF02782.11_FGGY_C_seed 105 377 !Q:13,13|15,15|17,24|27,32|36,36|43,68|72,77|90,90|97,97|105,135|147,147|150,150|152,169|172,172|176,182|184,184|186,186|188,188|190,195|198,198|202,203|207,224|228,228|231,236|260,271|275,295|298,305|314,314|316,316|321,321|324,341|348,349|351,351|357,358|360,360|371,372 Q:0,12|14,14|16,16|25,26|33,35|37,42|69,71|78,89|91,96|98,104|136,146|148,149|151,151|170,171|173,175|183,183|185,185|187,187|189,189|196,197|199,201|204,206|225,227|229,230|237,259|272,274|296,297|306,313|315,315|317,320|322,323|342,347|350,350|352,356|359,359|361,370|373,376 EEEEESSSEEEEE-E?T--------TS??--??SSS?EEEEEE--------------------------EET------TEEEEEEEEEES?SHHHHH-HHHHTTS-------------------------------SSSTTTHHHHH-HT?S??----------------SS?EEE-----??T-T?B?T------TT?BTT??EEE------------------EEE?TT??----HHHHHHHHHHHHHHHHHHHHHHH------------HTT---------------------TS??---???EEEESGGG-G?HHHH-HH------------------HHHHHT--S?EEEES?-S?HHHHHHHHHH--HHHH 1BWF|O PF02783.10_MCR_beta_N_seed 7 182 !Q:0,0|6,6|10,10|22,22|26,26|55,56|61,63|66,71|88,88|95,95|110,111|118,118|142,143|164,164|167,167|171,171|174,175|179,179 Q:1,5|7,9|11,21|23,25|27,54|57,60|64,65|72,87|89,94|96,109|112,117|119,141|144,163|165,166|168,170|172,173|176,178|180,181 ?EEEEE?TTS?EEEEEEEGGGG?TTT?HHHHHHHHHHHHEEEEEHHHHHHHHHHT??SSTT???TT??????TGGGHHHHHHHHHHHH?SSTTSS?EEEEEGGGTEEEEE??HHHHHT?SSSTHHHHHHHHHHHHHHHHHHT??TTTHHHHHHHHHTTTTTSSS?TT?SEE?SS??GGG?SS 1HBN|B PF02784.11_Orn_Arg_deC_N_seed 17 293 !Q:3,4|17,17|20,25|35,37|49,55|60,60|71,74|77,78|85,86|89,90|101,104|106,107|124,124|127,131|138,159|161,161|165,167|180,181|189,191|193,194|216,216|220,225|229,235|239,249|252,252|269,276|279,279|284,285 Q:0,2|5,16|18,19|26,34|38,48|56,59|61,70|75,76|79,84|87,88|91,100|105,105|108,123|125,126|132,137|160,160|162,164|168,179|182,188|192,192|195,215|217,219|226,228|236,238|250,251|253,268|277,278|280,283|286,292 EHH--HHHHHHHHHHHH?TT------EEEEEEGGG???HHHHHHHHHHT--?----EEEE?SHHHHHHHHH----TT??GGGEEE??SS??HHHHHHHHHT----T??EEEESSHHHHHHHHHH?TT?----EEEEEE???-??????????-----???B?TTT---HHHHHHHHHHTT-?EEEEEEE???S??SSTHHHHHHHHHHHHHHHHHH-HHT??--??EEE???????SSS?----------SS?HHHHHHHHHHHHHHHS??-----?TT?EEEE??SHHHHGG 1SZR|A PF02785.14_Biotin_carb_C_seed 109 164 !Q:7,9|14,18|20,27|29,29|34,65|73,76|78,82|84,85|87,88|92,93|102,103|119,119|122,122|124,125|129,130|132,133|151,157 Q:0,6|10,13|19,19|28,28|30,33|66,72|77,77|83,83|86,86|89,91|94,101|104,118|120,121|123,123|126,128|131,131|134,150|158,163 EEEEESS--?TTTT-----S-????-?-B?SEEE-?---------------?-----------???TTEEEEE?-??T-----T?-B??SSS??EEEEEEEE--ESSHHHHHHHHHHHH-HH?E--EES--S??THHHHHHHHHSHHHHTT-----??SSSHHH 3HO8|A PF02786.12_CPSase_L_D2_seed 16 216 !Q:13,14|17,17|23,24|38,38|46,52|54,54|58,58|74,82|88,89|92,92|106,106|115,117|120,121|126,126|132,132|135,136|156,156|161,161|169,171|182,182|184,185|196,198|210,212|214,215 Q:0,12|15,16|18,22|25,37|39,45|53,53|55,57|59,73|83,87|90,91|93,105|107,114|118,119|122,125|127,131|133,134|137,155|157,160|162,168|172,181|183,183|186,195|199,209|213,213 SHHHHHHHHHHTT??BS?EEEEE??SSHHHHHHHHHHH?SSEEEEE???????S?EEE?SGGGHHHHHHHHHHS?????????EEEEE??SS?EEEEEEEEEESSS?EEEEEEEE???EE--TTEE?EEEES?SS??HHHHHHHHHHHHHHHHHHT?EEEE-EEEEEEE---TTEEEEEEEE?S??TTHHHHHHHH???HHHHHHHHHTT???S?? 3ORQ|A PF02787.14_CPSase_L_D3_seed 95 163 !Q:3,3|5,7|11,11|24,24|29,29|38,41|56,56|63,65|70,71|73,78|89,90|96,99|102,108|110,111|114,122|130,130|136,138|143,144|151,156 Q:0,2|4,4|8,10|12,23|25,28|30,37|42,55|57,62|66,69|72,72|79,88|91,95|100,101|109,109|112,113|123,129|131,135|139,142|145,150|157,162 HHH-H---HHS?BTTHHHHHHHHH-HHTB?HHHHHHHH-???HHHHHHHHHHHHHH-HHHHHH---HHHH??H------HHHHHHHHTT??HHHHH----HH-------T--TS--------?HHHHHHH-HHHHT???EEEE??SBTTSS??-???EEEEES 1BXR|A PF02788.11_RuBisCO_large_N_seed 16 133 !Q:5,5|8,11|14,14|24,24|27,28|43,45|48,49|56,56|61,62|70,70|76,76|84,84|89,93|96,98|126,127 Q:0,4|6,7|12,13|15,23|25,26|29,42|46,47|50,55|57,60|63,69|71,75|77,83|85,88|94,95|99,125|128,132 HHHHB?TT????TT?EEEEEEEEE?TT??HHHHHHHHHHHTTT?-?SS??GGGGGS?HHHH??EEEEEEE?TTSSS?EEEEEEE?GGGS?----TT--?HHHHHHHHHSSGGGBTTEEEEEEEEEE??HHHHT 1RBA|A PF02789.12_Peptidase_M17_N_seed 103 177 !Q:3,4|7,16|22,22|26,33|38,38|44,44|55,58|61,61|65,66|70,70|72,72|74,74|76,78|87,88|92,103|121,121|123,124|130,130|134,138|140,140|145,145|147,150|166,170|173,173|176,176 Q:0,2|5,6|17,21|23,25|34,37|39,43|45,54|59,60|62,64|67,69|71,71|73,73|75,75|79,86|89,91|104,120|122,122|125,129|131,133|139,139|141,144|146,146|151,165|171,172|174,175 EEE--EE----------TTTEE?HHH--------HHHH-TTSSS-HHHHHHHHTS????TT?EEE--EES?T-T?S---SSEEEEEE??STT?---------??HHHHHHHHHHHHHHHHH-S??SEEEE?GGG-----S?BTTB?H----HHHHHHHHHHHHHHH???-?TT?SS? 2EWB|A PF02790.10_COX2_TM_seed 32 93 !Q:0,2|5,6|8,14|50,56|58,61|63,66|69,69 Q:3,4|7,7|15,49|57,57|62,62|67,68|70,92 ???TT??S---????SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS?------S????S????TT-HHHHHHHHHHHHHHHHHHHHHHH 1V55|B PF02792.9_Mago_nashi_seed 3 143 !Q:0,0|34,35|39,41|49,49|68,70|74,76|91,92|99,102|111,111|138,142 Q:1,33|36,38|42,48|50,67|71,73|77,90|93,98|103,110|112,137 ?EEEEEEEEEEETTEEEEEEEEEETTTEEEEEEE??GGG???EEEEEEE?HHHHHHHHHHHHHHTGGG???TTS???BTTBEEEEEEEETT??EEEEEE????HHHHHTSS?HHHHHHHHHHHHHHHHHHHHHHHHHH????? 1P27|A PF02793.17_HRM_seed 131 110 !Q:0,1|4,5|8,8|11,12|15,16|21,21|27,28|33,34|36,37|39,63|66,70|77,77|80,83|85,85|87,87|89,89|92,95|97,97|100,101|103,103|107,109 Q:2,3|6,7|9,10|13,14|17,20|22,26|29,32|35,35|38,38|64,65|71,76|78,79|84,84|86,86|88,88|90,91|96,96|98,99|102,102|104,106 ??EE??EE?SS-?EE??EETT?EEEEE??SSST--T??T-------------------------TS-----EEEEEB?TT----S?B?B?TT----T?SB??B?GGG??? 3C59|A PF02796.10_HTH_7_seed 14 54 !Q:0,3|9,9|29,31|41,42|53,53 Q:4,8|10,28|32,40|43,52 ????SSSTT?SSHHHHHHHHHHHHHHHTT-??HHHHHHHHT??HHHHHHHHTT? 1HCR|A PF02797.10_Chal_sti_synt_C_seed 21 157 !Q:9,9|12,12|17,17|28,30|32,32|54,62|71,72|87,88|103,103|105,105|126,126|133,133|155,155 Q:0,8|10,11|13,16|18,27|31,31|33,53|63,70|73,86|89,102|104,104|106,125|127,132|134,154|156,156 EEEEEEEEE?TT?TTSS?EEEETTEEEE???S?HHHHHHHHHHHHHHHHHGGGT??------?TTSSEEEE??SSHHHHHHHHHHHT??GGGGHHHHHHHHHH?B?GGGHHHHHHHHHHHHHHHTT?SBTTTT?SEEEEEEEETTTEEEEEEEEE?B 3OIT|A PF02798.15_GST_N_seed 53 105 !Q:10,11|22,24|28,29|33,34|38,41|45,49|60,71|74,75|83,88 Q:0,9|12,21|25,27|30,32|35,37|42,44|50,59|72,73|76,82|89,104 EEEEEESSSG--GGHHHHHHHH---HTT??EEE--EEE????SSS??--?HHHHHHHTTS?----------?SS??SSEEEET------TEEEESHHHHHHHHHH 2NTO|A PF02799.10_NMT_C_seed 39 239 !Q:5,7|10,16|25,27|30,31|35,35|39,40|59,59|65,67|77,77|81,84|88,89|97,97|100,101|103,103|113,114|118,118|120,120|122,122|124,124|128,128|138,138|143,143|145,145|148,148|173,173|176,176|182,182|184,184|196,196|212,216|220,220|225,225|227,227|231,231|233,233|235,238 Q:0,4|8,9|17,24|28,29|32,34|36,38|41,58|60,64|68,76|78,80|85,87|90,96|98,99|102,102|104,112|115,117|119,119|121,121|123,123|125,127|129,137|139,142|144,144|146,147|149,172|174,175|177,181|183,183|185,195|197,211|217,219|221,224|226,226|228,230|232,232|234,234 HTTSS???TT??-----HHHHHHHH???SS??STT-EEE??GGGHHHHHHHHHHHHTTS-SEEEE?-?HHHHHHHHS?SSS--??TTT??EEEEEEE?TT--S?EEEEEEEEE??EEE?S?S-S?SEE?EEEEEEEEE?TTTT?S?TT?HHHHHHHHHHHHHHHHHHHHHHHH-TT?SEEEE?S?TTGGGTTTTTT?EEEEEEEEEEEETEE?????BSB?TTSS-B?TTT?B?B???? 2WUU|A PF02800.15_Gp_dh_C_seed 71 179 !Q:9,9|13,13|24,26|34,38|41,41|50,51|53,54|58,59|74,74|79,80|84,84|86,86|89,89|101,104|118,124|135,135|137,139|146,147|149,150|159,159|164,168 Q:0,8|10,12|14,23|27,33|39,40|42,49|52,52|55,57|60,73|75,78|81,83|85,85|87,88|90,100|105,117|125,134|136,136|140,145|148,148|151,158|160,163|169,178 HHHHHHHHH-HHH?EEEEEEEEEE???TTSBSSS???--TT?SGGGSBTT--T??EEE??TTTTHHHHHSGGGT-TSEE??EEE?S?SS?EEEEEEEEESS?-??HHHHHHHHHHHHH-------TTTBTTEEEE?S???GGGGTT??S--SEEEETTT?EEEE-----TTEEEEEEEE 3DMT|A PF02801.17_Ketoacyl-synt_C_seed 165 137 !Q:0,0|11,13|15,15|20,22|27,28|32,36|46,48|52,53|57,62|82,91|95,96|100,100|106,106|108,108|130,132|135,136 Q:1,10|14,14|16,19|23,26|29,31|37,45|49,51|54,56|63,81|92,94|97,99|101,105|107,107|109,129|133,134 ?EEEEEEEEEE??-S?SSSS???HHHH--HHH-----HHHHHHHHT??-GGG??EEE??????TTHHHHHHHHHHTTTTTSS?---------TTS??EEE?THHHH?B?GGGTTHHHHHHHHHHHHHTEE???TT?? 1F91|A PF02803.13_Thiolase_C_seed 22 143 !Q:0,2|14,15|17,17|37,39|43,43|49,50|64,66|68,84|91,92|97,99|120,121|142,142 Q:3,13|16,16|18,36|40,42|44,48|51,63|67,67|85,90|93,96|100,119|122,141 ???SEEEEEEEEEE??G-GGGGGTHHHHHHHHHHHHT??-GGG?SEEEE??SBHHHHHHHHHHH???G-----------------GGBSTT??HHHH???GGGHHHHHHHHHHHHHHHHT-?SEEEEEEEETTTEEEEEEEE? 2WL4|A PF02805.11_Ada_Zn_binding_seed 150 69 !Q:5,5|11,13|16,16|20,20|32,32|35,36|39,41|59,59|62,62|68,68 Q:0,4|6,10|14,15|17,19|21,31|33,34|37,38|42,58|60,61|63,67 HHHHH-HHHTT?--TT?TTT?EEEETTTTEEE?TT??SS???GGGEEEESSHHHHHHTT?EE?TTTSS? 1EYF|A PF02806.13_Alpha-amylase_C_seed 246 178 !Q:17,28|31,32|34,35|42,45|48,50|55,57|59,59|62,63|65,68|70,77|83,86|94,97|99,109|111,112|114,121|124,134|137,138|140,140|145,150|152,155|159,163|170,170|173,173|176,177 Q:0,16|29,30|33,33|36,41|46,47|51,54|58,58|60,61|64,64|69,69|78,82|87,93|98,98|110,110|113,113|122,123|135,136|139,139|141,144|151,151|156,158|164,169|171,172|174,175 EEEEEETTTTEEEEEEE---?--------TT??E--EEEEEE---?SS?-?EEEE-??B?SS-?S----E--------EEEEE----ETTSTGG----G??------??-S??S?-------EE?----------BS??B-TTBS-----?B?--?EEE----?TTEEEE-EE-EE?? 1JI2|A PF02807.10_ATP-gua_PtransN_seed 91 88 !Q:0,2|5,9|16,17|27,31|35,36|47,49|52,52|55,55|57,61|69,70|87,87 Q:3,4|10,15|18,26|32,34|37,46|50,51|53,54|56,56|62,68|71,86 ???TT---??BHHHHH??HHHHHHHTT???--TTS??HHHHHHHHHH???BT-TB?B?????SSSTHHH--HTHHHHHHHHHHHTTS? 3DRE|A PF02809.15_UIM_seed 46 18 !Q:0,1 Q:2,17 ??HHHHHHHHHHHHHHHT 1UEL|B PF02810.10_SEC-C_seed 183 22 !Q:0,1|7,7|16,16|19,21 Q:2,6|8,15|17,18 ??BTTTT?BSSHHHHH-TT??? 2I9W|A PF02811.14_PHP_seed 69 557 !Q:0,1|5,6|10,14|18,22|28,30|37,38|40,41|43,43|48,49|51,52|54,55|58,60|71,100|103,107|109,112|116,117|127,319|322,333|342,343|350,377|389,401|403,407|413,413|417,417|419,421|428,434|441,442|456,466|478,509|515,515|523,524|527,527|532,552 Q:2,4|7,9|15,17|23,27|31,36|39,39|42,42|44,47|50,50|53,53|56,57|61,70|101,102|108,108|113,115|118,126|320,321|334,341|344,349|378,388|402,402|408,412|414,416|418,418|422,427|435,440|443,455|467,477|510,514|516,522|525,526|528,531|553,556 ??SSB??TTS-----TTT???-?HHHHH---HHHHHH??S--S?EEEE??B--T??SS---HHHHHHHHHH------------------------------HT----?E----EEE--EEEEEEESS?------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TT?????-??????EEEEEEEE?-SHHHHH----------------------------HHHHHHHHHHH-------------T-----SBSSS-BEE?H---HHHHHT------?TTEEEE??STTBHHHHHHHTT?----------HHHHHHHHHHH--------------------------------HHHTT-TSEEEEE??SS?HHHH---------------------HHHH 3QY7|A PF02812.13_ELFV_dehydrog_N_seed 262 207 !Q:0,0|3,8|17,22|24,24|27,27|29,29|42,42|46,46|50,51|55,55|58,58|60,91|94,97|109,110|117,117|119,120|127,129|131,139|142,143|146,153|157,157|172,173|175,175|182,183|185,185|188,189|198,199 Q:1,2|9,16|23,23|25,26|28,28|30,41|43,45|47,49|52,54|56,57|59,59|92,93|98,108|111,116|118,118|121,126|130,130|140,141|144,145|154,156|158,171|174,174|176,181|184,184|186,187|190,197|200,206 ?SE------EEEEEEEE------E?TT-S?EEEEEEEEEEEE?TTS-SEE??EEE-ES-S------------------------------??HH----HHHHHHHHHHH--HHHHHT?S??EEEEEE---E??-------GG--GS?-------HHH-HHHHHHHHHHHTGG--G?BTTTEE??B?TT??HHHHHHHH--HHHHHHH 1C1D|A PF02813.9_Retro_M_seed 3 86 !Q:20,20|36,36|39,39|63,64|85,85 Q:0,19|21,35|37,38|40,62|65,84 HHHHHHHHHHHHHHHTTTSS?SSHHHHHHHTGGGTT?TT?GGGGGSTTTTHHHHHHHHHTTTS??SSSSSHHHHHHHHHHHHHHH? 1A6S|A PF02814.10_UreE_N_seed 70 72 !Q:0,1|3,3|9,11|14,16|24,24|30,30|37,37|40,42|48,48|52,57|65,65|70,70 Q:2,2|4,8|12,13|17,23|25,29|31,36|38,39|43,47|49,51|58,64|66,69|71,71 ??E-EGGGG---TT???EEEEEEE?GGGTT?SEEEEE?TT??-EEEEE?SSS-??-??TTEEEEE?SSEE-E 3NY0|A PF02815.14_MIR_seed 30 301 !Q:0,6|11,17|29,38|41,41|47,50|55,57|64,66|70,70|76,112|121,122|129,175|183,183|185,213|216,219|222,222|227,242|262,269|274,275|279,283|290,291|294,295|298,298 Q:7,10|18,28|39,40|42,46|51,54|58,63|67,69|71,75|113,120|123,128|176,182|184,184|214,215|220,221|223,226|243,261|270,273|276,278|284,289|292,293|296,297|299,300 ???????EEEE-------EETTTTEEEEE----------EE?SSSEE----EEEE???SSSGGG???GGG?EEEEE??????-----------???????----------???EEEEETTT??EEEEEE??????????-------------????????????????????????EEEEEES?S----------------------------?SG----GG?EEEE????????????????BEEEEGGGTEEEEEEEEES------??SSSS??EEE-----EEEESS??SS??EE-EE 4I6I|A PF02816.13_Alpha_kinase_seed 63 361 !Q:3,3|23,30|33,33|38,38|40,41|44,44|51,51|54,54|62,90|93,94|96,125|149,157|160,164|166,179|181,183|185,185|189,189|193,195|199,217|224,232|234,238|242,242|244,244|247,248|250,250|252,264|266,267|271,275|290,290|294,295|300,302|304,310|313,313|315,315|319,319|321,322|324,326|328,331|333,336|339,340|351,351|353,357 Q:0,2|4,22|31,32|34,37|39,39|42,43|45,50|52,53|55,61|91,92|95,95|126,148|158,159|165,165|180,180|184,184|186,188|190,192|196,198|218,223|233,233|239,241|243,243|245,246|249,249|251,251|265,265|268,270|276,289|291,293|296,299|303,303|311,312|314,314|316,318|320,320|323,323|327,327|332,332|337,338|341,350|352,352|358,360 SEE?SSEEEEEEEEEEEEESTTS????????SS?GGGB?S??SS?SHHHHT?TT?EEEEEEE??------------------------???TT??H------------------------------HHHHHHHHHHHHHHHHHHHHHHT-------??SS?---?E--------------E???E-EEE?TTS???SSS?----------------??EEEEEE?------??S----?EEE?B?SS--S?B------------?S??HHH-----HHHHHHHHHHTTTS?EEE??EEET---T-------EE?S?EEE?T--T-??S----S--?-TT??HHHHHHHHHH-H?-???HHH 1IAH|A PF02817.12_E3_binding_seed 58 43 !Q:0,5|17,18|21,23|26,29|34,36 Q:6,16|19,20|24,25|30,33|37,42 ??????HHHHHHHHHTT??GG---GS?-??STTS???TTTTTT 2F5Z|K PF02819.10_Toxin_9_seed 6 47 !Q:2,2|7,9|13,14|19,20|24,25|29,29|31,31|35,35|37,42|46,47 Q:0,1|3,6|10,12|15,18|21,23|26,28|30,30|32,34|36,36|43,45 SB?STTB???TTS??BSSS?-EEE??SSS?S?EEE-S??????TTT?- 1OMA|A PF02820.13_MBT_seed 18 79 !Q:0,0|26,26|35,35|39,43|50,51|56,56|65,66|69,69|73,78 Q:1,25|27,34|36,38|44,49|52,55|57,64|67,68|70,72 ?EEEEEETTEEEEEEEEEEEEEETTE-EEEEETTS?TTS----?EEEETT-?SSEE?TTHHHHHT??EE?STT?????? 1WJQ|A PF02821.11_Staphylokinase_seed 11 132 !Q:2,2|4,4|18,19|23,23|27,29|36,36|39,39|57,57|77,77|79,81|84,85|89,90|94,97|99,100|102,104|108,111|113,117 Q:0,1|3,3|5,17|20,22|24,26|30,35|37,38|40,56|58,76|78,78|82,83|86,88|91,93|98,98|101,101|105,107|112,112|118,131 SB?S?EEEEEEEEEEESS??TTS?TTB???EEEEEE?TT?EEEHHHHHHHHHHHHHH-HSTTEEEEEEEEEEEEETT?S??-EE??SSS??EEE????B??B???SSS????B??---EEEEEEEEEEEEES 1L4Z|B PF02822.9_Antistasin_seed 60 38 !Q:1,1|5,6|8,10|12,14|17,17|21,22|24,24|27,28|30,32 Q:0,0|2,4|7,7|11,11|15,16|18,20|23,23|25,26|29,29|33,37 E?SEE--E---S???TT?EEE?-T-TS-?E---EEEEE 1HIA|I PF02823.11_ATP-synt_DE_N_seed 327 106 !Q:0,0|6,6|9,9|11,13|15,17|19,19|23,23|28,28|32,32|34,41|43,44|46,46|48,50|52,54|57,59|61,76|78,80|82,83|85,86|89,89|91,93|95,95|101,102|105,105 Q:1,5|7,8|10,10|14,14|18,18|20,22|24,27|29,31|33,33|42,42|45,45|47,47|51,51|55,56|60,60|77,77|81,81|84,84|87,88|90,90|94,94|96,100|103,104 ?EEEEB?SS?B???S?-?S?EEE?BSSS?EEE?S????????B?-S-S???B?--TT---S------??--------B??-B??S??EE-E?--S-SEEEE??SS? 3OAA|H PF02824.16_TGS_seed 61 78 !Q:5,6|10,12|16,18|26,27|36,36|39,39|59,59|62,62|65,68|74,74 Q:0,4|7,9|13,15|19,25|28,35|37,38|40,58|60,61|63,64|69,73|75,77 EEEEE??TTS???SSS--?EEEETTS??HHHHHHHH?TT?TTTEEEEEEBSTTSSSSSE-EE?SS????SSEEE?EEE 3HVZ|A PF02825.15_WWE_seed 14 91 !Q:13,13|18,19|25,26|30,31|43,43|45,49|53,53|61,62|78,84 Q:0,12|14,17|20,24|27,29|32,42|44,44|50,52|54,60|63,77|85,90 TSHHHHTEEEEEE?SSSS??SSEEE??HHH--HHHHHHHHHTT?S-----EEE-HHHHTSS??EEEETTTTEEEETTT?-----?EEEEEE 2A90|A PF02826.14_2-Hacid_dh_C_seed 161 260 !Q:11,13|21,24|28,42|45,47|49,50|52,58|61,61|67,68|81,81|85,86|92,92|95,104|108,110|116,117|120,122|130,130|136,140|147,147|149,149|157,157|160,165|170,170|172,172|177,177|197,198|202,212|214,219|222,233|236,239|242,244|247,251|255,255|258,258 Q:0,10|14,20|25,27|43,44|48,48|51,51|59,60|62,66|69,80|82,84|87,91|93,94|105,107|111,115|118,119|123,129|131,135|141,146|148,148|150,156|158,159|166,169|171,171|173,176|178,196|199,201|213,213|220,221|234,235|240,241|245,246|252,254|256,257|259,259 HHHHHHHHTTH---HHHHHHH----TTT----??--------?TT---T??B?----??TT?EEEEE??SHHHHHHHHHHH-HTT?-EEEEE?SS----??----HHH---HHHTT?-EE?-?HHHHHHH?SEEEE???-?STTTTT?B?HHHHHHS?TT?-----EEEE?S?GGGB?HHHHHHHHHHTSSSEEEES??SSS-----------S??----TT--------?---GG----GG--?TT-----EEE?SS?T 3ORQ|A PF02828.11_L27_seed 20 60 !Q:15,23|34,35|54,59 Q:0,14|24,33|36,53 HHHHHHHHHHHHTTS???------HHHHHHHHHT??TTHHHHHHHHHHHHHHTT????-- 1RSO|B PF02829.9_3H_seed 57 111 !Q:4,8|22,22|25,25|36,36|40,40|47,47|50,50|65,67|69,74|81,81|108,108|110,110 Q:0,3|9,21|23,24|26,35|37,39|41,46|48,49|51,64|68,68|75,80|82,107|109,109 EEEE--?-?GGGHHHHHHHHHH-TT?EEEEEEEEET-TTE-EEEEEE-EE?SHHHHHHHHHHHHH?-?S?----?STTGGG-GEEEEEEEESSHHHHHHHHHHHHHTT?B? 1J5Y|A PF02830.13_V4R_seed 52 75 !Q:1,1|9,9|11,11|14,16|19,21|34,41|47,50|57,57|62,62|64,66|74,74 Q:0,0|2,8|10,10|12,13|17,18|22,33|42,46|51,56|58,61|63,63|67,73 S?EEEEEES?S?TT???SS???HHHHHHHHHHHH--------HHHSS?--?EEEEEE?GGGT?S---SEEEEEE? 2OSD|A PF02831.10_gpW_seed 5 76 !Q:0,2|5,7|23,25|28,30|33,33|36,37|42,42|64,75 Q:3,4|8,22|26,27|31,32|34,35|38,41|43,63 ???HH---HHHHHHHHHHHHTTS???EE---EE?SS-?EEEE?TTTHHHHHHHHHHHHHHTTTT?-?????????? 1HYW|A PF02832.11_Flavi_glycop_C_seed 12 100 !Q:2,2|4,5|7,8|18,18|22,22|30,31|34,34|38,39|52,52|58,58|60,60|63,64|77,78|92,92 Q:0,1|3,3|6,6|9,17|19,21|23,29|32,33|35,37|40,51|53,57|59,59|61,62|65,76|79,91|93,99 TS?B??S-?EEEEEEEEE?SSS?EEEEEEE??SS?SEE??EEEEEETTEEEE?SEESS?S?EE??SSTTEEEEEEEE??SEEEEEEESSGGG?EEEEEEE 1N6G|A PF02833.9_DHHA2_seed 126 194 !Q:1,4|15,15|19,19|34,40|43,46|58,58|67,76|85,85|93,93|102,107|121,124|132,138|140,140|147,176|178,180 Q:0,0|5,14|16,18|20,33|41,42|47,57|59,66|77,84|86,92|94,101|108,120|125,131|139,139|141,146|177,177|181,193 H----HHHHHHHHGG-GGS?HHHHHTTSEEEEEE-------TT----EEEEEEEEEES?THHHHHHH----------HHHHHHHH-HHHHHTT?SEEEEEEE------ETTTTEEEEEEEE---?HHHHHHH???-???S-SEEEET------------------------------T???HHHHTHHHHHHHH 1WPM|A PF02834.11_LigT_PEase_seed 107 100 !Q:2,4|19,21|30,34|38,38|47,47|49,54|60,62|77,77|90,90|93,93 Q:0,1|5,18|22,29|35,37|39,46|48,48|55,59|63,76|78,89|91,92|94,99 EE?-?HHHHHHHHHHHHHH?--SSSEEEEE?---?GGG?EEEEEEEE-E??----HHHHH---HHHHHHHHHHTTSB?EEEEEEEEEEEE?SS-SEEEEE 1IUH|A PF02836.12_Glyco_hydro_2_C_seed 11 364 !Q:5,5|15,16|22,25|32,34|47,47|51,52|56,56|60,62|74,74|80,80|82,82|84,84|97,101|119,119|140,140|148,150|153,161|175,175|179,181|185,185|188,201|204,204|207,207|215,216|223,226|233,233|236,253|255,255|259,259|267,269|272,275|286,286|296,296|299,301|308,308|320,320|325,326|329,330|335,339|342,342|346,346|348,348|359,359 Q:0,4|6,14|17,21|26,31|35,46|48,50|53,55|57,59|63,73|75,79|81,81|83,83|85,96|102,118|120,139|141,147|151,152|162,174|176,178|182,184|186,187|202,203|205,206|208,214|217,222|227,232|234,235|254,254|256,258|260,266|270,271|276,285|287,295|297,298|302,307|309,319|321,324|327,328|331,334|340,341|343,345|347,347|349,358|360,363 EEEET-TEEEETTEE??EEEEE????BTTTBT???HHHHHHHHHHHH-HTT??EEE?TTS???TTHHHHHHHHT?EEEEE?S?B?GGGGHHHHHHTT?????TTTTHHHHHTTGGGTTT?GGGHHHHHHHHHHHHHHHTT?TTEEEEE??-BS?-----???HHHHHHHHHHHHH?TTS---EEE?TT?-------------TT?TT?SSEEEES??HHHHHH----HHHHHB?TT------------------S?BSS?EEEEEES???SS????HHHHHHHHHH?TTEEEEEES?SB???EEEEEE?TTTSSEEEEEE?TTTT??SS??GGGG??--?SB?TTS?B?HHHHHHHHHT?SEEE 1HN1|A PF02837.13_Glyco_hydro_2_N_seed 88 310 !Q:0,0|6,7|9,15|26,50|54,54|57,57|62,75|78,85|89,89|97,97|102,102|104,104|106,107|114,114|117,130|137,139|144,145|148,158|160,160|171,172|176,180|182,184|186,186|193,194|211,211|214,214|218,218|223,223|227,228|232,235|244,249|251,252|259,291|296,297|300,300|302,302|309,309 Q:1,5|8,8|16,25|51,53|55,56|58,61|76,77|86,88|90,96|98,101|103,103|105,105|108,113|115,116|131,136|140,143|146,147|159,159|161,170|173,175|181,181|185,185|187,192|195,210|212,213|215,217|219,222|224,226|229,231|236,243|250,250|253,258|292,295|298,299|301,301|303,308 ?TTEEE??E-------EEEEEEEESG-------------------------GGS?TT-TTST--------------TS??------TTS-EEEEESS?GGGG-T?S??EEESSS?TT--------------SSGGGT???BTTB??ST-----------T?EEEEEEEEEE??GGG-----T---T?EEEEEE??EESEEEEEETTEEEEE-EE?TTS?EEEE?GGG??SSE----EEEEEEEE------S??GGGGGB-------------------------------??SEEE??EE?S?EEEEEE? 1HN1|A PF02838.10_Glyco_hydro_20b_seed 143 264 !Q:0,4|7,8|12,13|15,15|17,18|23,26|29,32|34,34|36,36|42,43|46,48|51,55|58,59|61,65|67,70|72,72|74,74|79,79|81,81|83,89|93,96|99,107|110,113|116,124|126,129|132,145|148,148|150,150|152,152|156,157|161,165|172,173|178,178|181,181|186,186|190,193|195,199|222,224|227,240|242,249|252,253|255,255|258,258|263,263 Q:5,6|9,11|14,14|16,16|19,22|27,28|33,33|35,35|37,41|44,45|49,50|56,57|60,60|66,66|71,71|73,73|75,78|80,80|82,82|90,92|97,98|108,109|114,115|125,125|130,131|146,147|149,149|151,151|153,155|158,160|166,171|174,177|179,180|182,185|187,189|194,194|200,221|225,226|241,241|250,251|254,254|256,257|259,262 ??-??SS??SEE--E-E--EEEE----EE??--S-E-EEEES--TT---TS?----HH--H-----H----H-H-HHHH-H-H-------HTT-?--EE?--------SS?--?TT---------S---?EE--------------EE-E-E-TTS??HHH-----HHHTTT??STTS?TT?EEEE-EET----T-----EEEEEESSHHHHHHHHHHHHHH?--BT--------------T--------EE--E-EE-EEEE? 2J47|A PF02839.9_CBM_5_12_seed 135 66 !Q:0,1|3,4|7,7|9,11|13,13|15,15|17,21|25,25|29,30|35,36|39,39|41,42|44,48|54,63 Q:2,2|5,6|8,8|12,12|14,14|16,16|22,24|26,28|31,34|37,38|40,40|43,43|49,53|64,65 ??B??TT-S?--B?T-T----?EEE-ETT--EEEE?-SS?B?-S?---?BTTBT----------TS 1O6I|A PF02840.10_Prp18_seed 29 201 !Q:2,2|21,25|37,37|40,62|81,84|86,88|90,90|110,116|132,135|137,170|172,175|198,200 Q:0,1|3,20|26,36|38,39|63,80|85,85|89,89|91,109|117,131|136,136|171,171|176,197 TT?STTHHHHHHHHHHHHHHH-----HHHHHHTGGGS?HH-----------------------HHHHHHHHHHHHHHHHHH----T--?S?HHHHHHHHHHHHHHTSGGG-------HHHHHHHHHHHHHTB????S???????????-----??????????----?--?B????HHHHHHHHHHHHHHHHHHHHHH?-? 1DVK|A PF02841.9_GBP_C_seed 23 330 !Q:4,4|25,26|59,61|64,64|89,94|170,172|174,176|187,188|192,214|217,217|227,227|231,231|289,289|314,314 Q:0,3|5,24|27,58|62,63|65,88|95,169|173,173|177,186|189,191|215,216|218,226|228,230|232,288|290,313|315,329 TTEE?BHHHHHHHHHHHHHHHHHTS??BHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?-?SS?SSHHHHHHHHHHHHHHHHHHHHHH????--GGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTSSTTHHHHHHHHHHHHHHHHHHS---S???TTHHHHHHHH--HHH-----------------------TH-HHHHHHHHH?SSS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHH 2B8W|A PF02843.11_GARS_C_seed 94 169 !Q:12,17|20,27|29,29|31,38|41,42|53,71|73,91|93,114|118,118|146,148|150,150|152,152|156,157|159,159|163,165 Q:0,11|18,19|28,28|30,30|39,40|43,52|72,72|92,92|115,117|119,145|149,149|151,151|153,155|158,158|160,162|166,168 EEEEEEEEETTT------TS?-???-??B?B??---?--SS??TTEEEEESSE-------------------E-------------------E??--??---------------?EEE?SSEEEEEEEEESSHHHHHHHHHHHTTT?--B?T-TEE??S?TTH---HHH 2YS7|A PF02844.10_GARS_N_seed 135 134 !Q:7,7|19,19|22,22|33,36|40,42|46,47|51,54|57,66|69,69|75,76|84,84|90,90|106,109|112,121|125,126 Q:0,6|8,18|20,21|23,32|37,39|43,45|48,50|55,56|67,68|70,74|77,83|85,89|91,105|110,111|122,124|127,133 EEEEEEE?SHHHHHHHHHH-TT?TTEEEEEEEE?--?HHH---HHS--TTE----EE???------?TT?HHHHH--HHHHHTT?SEEEE?SHHHHHTTHHHHHHH----TT------??--EES??TTTTHHH 2YS7|A PF02845.11_CUE_seed 132 44 !Q:0,0|5,6|13,13|17,17|31,31 Q:1,4|7,12|14,16|18,30|32,43 ?HHHH--HHHHHH?SSS?HHHHHHHHTTTTT?HHHHHHHHHHSS 2DI0|A PF02847.12_MA3_seed 29 136 !Q:10,10|16,17|26,26|30,31|33,34|52,55|76,76|90,90|99,114|134,135 Q:0,9|11,15|18,25|27,29|32,32|35,51|56,75|77,89|91,98|115,133 HHHHHHHHHH-HHHHH??HHHHHHHH-HTT??G--GGHHHHHHHHHHHHTTT---?HHHHHHHHHHHHHHHHTTSS?HHHHHHHHHHHHH-HHHHHTTT---------------?TTHHHHHHHHHGGGGSTTS?? 2HM8|A PF02852.17_Pyr_redox_dim_seed 102 145 !Q:0,1|5,5|15,19|21,21|29,36|46,55|57,57|65,74|83,83|86,86|96,96|102,103|116,119|123,123|125,125|130,132|135,135|145,145 Q:2,4|6,14|20,20|22,28|37,45|56,56|58,64|75,82|84,85|87,95|97,101|104,115|120,122|124,124|126,129|133,134|136,144 ??EEE?SSSEEEEEE?---?H-HHHHHTT??------EEEEEEEGG----------G?HHHHHTT?------???EEEEEEET-TT?BEEEEEEEE-TTHHH--HHHHHHHHHHTT?---BHH-H-HHTS???TT?TTHHHHHHH- 1YQZ|A PF02854.14_MIF4G_seed 41 374 !Q:9,9|12,17|28,31|33,39|51,53|60,60|62,67|83,106|124,160|182,185|187,187|190,190|195,200|209,209|212,229|247,300|321,353|356,356 Q:0,8|10,11|18,27|32,32|40,50|54,59|61,61|68,82|107,123|161,181|186,186|188,189|191,194|201,208|210,211|230,246|301,320|354,355|357,373 HHHHHHHHT?SS---???HHHHHHHHTT????S-------HHHHHHHHHHH---HHHHHH?G------GGHHHHHHHHHHHTT?????----------?????????HHHHHHHHHHHHHHHHT????????????----?????????????????????SSHHHHHHHHHHHHHHHHTTT?---S?HH-HHHH------HHHHHHHS?SH------------------HHHHHHHHHHHHHHHHH?----------------------------------------------------?TTTHHHHHHHHHHHHHHHHS--------------------------------?SS?HHHHHHHHHHHHHHHTT 3RK6|A PF02861.15_Clp_N_seed 167 54 !Q:1,1|10,10|14,14|26,27|39,40|53,53 Q:0,0|2,9|11,13|15,25|28,38|41,52 H-HHHHHHTT?SSB?HHHHHHHHHHH??SHHHHHHHHTT??HHHHHHHHHHHH? 3PXG|A PF02863.13_Arg_repressor_C_seed 146 75 !Q:11,11|21,22|25,25|37,39|42,43|50,50 Q:0,10|12,20|23,24|26,36|40,41|44,49|51,74 HHHHHEEEEEE?SSEEEEEES--TT?HHHHHHHHHTT-??TT--EEEEEE?SSEEEEEESSHHHHHHHHHHHHTT 1XXC|A PF02864.10_STAT_bind_seed 9 269 !Q:8,8|11,11|14,14|22,23|33,34|40,40|45,68|75,75|77,77|82,89|102,118|121,121|124,125|133,133|136,138|146,146|148,148|172,174|177,177|184,188|206,211|224,224|226,226|228,233|236,239|248,248 Q:0,7|9,10|12,13|15,21|24,32|35,39|41,44|69,74|76,76|78,81|90,101|119,120|122,123|126,132|134,135|139,145|147,147|149,171|175,176|178,183|189,205|212,223|225,225|227,227|234,235|240,247|249,268 EEEEEEEE?TT?TT?TTEEETT??EEEEEEESS??TTTTT?EEEE???????????????------???EEEESS?E-EEEB????????EEEEEEEEEEEE?????????????????TT?EE??EEEEEEE?SS--?EEEEEEE?S?EEEESSTTSHHHHHHHHHHHHHS???SS?SGGGGS?????HHHHHHHHHHHHHHHSS--????TTTTTTTTHHHH?S?S?----?SS????HHHHHTSB?SSSSSBHHHHHHHHHHHHHH 3CWG|A PF02865.12_STAT_int_seed 22 133 !Q:0,0|9,9|16,16|21,22|26,27|41,42|44,44|51,56|82,82|84,84|96,96|104,104|107,107|130,130 Q:1,8|10,15|17,20|23,25|28,40|43,43|45,50|57,81|83,83|85,95|97,103|105,106|108,129|131,132 ?HHHHHTTS?TTTHHH-HHTT??TTS-?HHHHHHTHHHHHH--S?HHHHTT-----?HHHHHHHHHHHHHHHHHHHHHHHHH-T?HHHHHHHHHHH-HHHHHHH-TT?HHHHHHHHHHHHHHHHHHHHTT?GG 1YVL|A PF02866.13_Ldh_1_C_seed 19 232 !Q:11,21|25,27|31,33|38,40|42,43|47,47|52,52|55,55|59,59|76,78|101,103|105,107|117,120|129,136|149,149|153,153|155,174|188,192|197,205|214,214|231,231 Q:0,10|22,24|28,30|34,37|41,41|44,46|48,51|53,54|56,58|60,75|79,100|104,104|108,116|121,128|137,148|150,152|154,154|175,187|193,196|206,213|215,230 THHHHHHHHHH-----------HHH---HHT?-?GGGE---E??EEB?SSTT?EE?GGG?EETTEEHHHHHTTSSS??-HHHHHHHHHHHHHHHHHHHHHH---S???HHHHHHHHH----HHHHHHTT?------?EEEEEEEEESSB-TTB?S--------------------EEEEEEEEEETTE-----EEEE-??-??-??HHHHHHHH-HHHHHHHHHHHHHHTS? 8LDH|A PF02867.10_Ribonuc_red_lgC_seed 136 1091 !Q:0,2|7,13|15,15|17,17|21,25|42,43|49,49|52,52|54,55|60,60|65,65|69,69|84,94|100,100|112,114|116,171|179,179|181,182|187,190|195,201|203,203|209,209|216,254|258,259|262,268|279,308|312,319|322,323|343,343|356,356|359,363|365,377|379,383|385,400|404,409|413,468|470,470|472,474|485,485|489,563|565,565|587,589|591,591|598,625|631,633|639,639|649,650|680,680|682,682|685,687|689,707|710,711|720,724|731,756|758,760|763,856|868,870|872,872|874,875|877,881|887,888|891,891|893,894|898,900|902,902|914,919|924,924|936,949|961,979|981,982|985,985|987,987|990,990|997,998|1000,1003|1006,1012|1015,1018|1033,1033|1036,1040|1043,1059|1061,1062|1064,1067|1083,1083|1089,1089 Q:3,6|14,14|16,16|18,20|26,41|44,48|50,51|53,53|56,59|61,64|66,68|70,83|95,99|101,111|115,115|172,178|180,180|183,186|191,194|202,202|204,208|210,215|255,257|260,261|269,278|309,311|320,321|324,342|344,355|357,358|364,364|378,378|384,384|401,403|410,412|469,469|471,471|475,484|486,488|564,564|566,586|590,590|592,597|626,630|634,638|640,648|651,679|681,681|683,684|688,688|708,709|712,719|725,730|757,757|761,762|857,867|871,871|873,873|876,876|882,886|889,890|892,892|895,897|901,901|903,913|920,923|925,935|950,960|980,980|983,984|986,986|988,989|991,996|999,999|1004,1005|1013,1014|1019,1032|1034,1035|1041,1042|1060,1060|1063,1063|1068,1082|1084,1088|1090,1090 ???EEEE-------E?S?SSH-----HHHHHHHHHHHHHHHT??EEEEE?TT-S??EEEE?TTTS?EEE?HHHHHHHHHHHHHH???????????EEEEE?TTBTTHHHHHH---H?-?????????------------------------------------------???EEEEEEE?H--HHHH----HHHT-------T?EEEEB?TTTSTT---------------------------------------STT??TH-------HHHHHHHHHH------------------------------HTT-----?-?SE--EEEHHHHHHHHHHHHHHHS?SEEEEHHHHHHT?TT-----G-------------G-----G---------???????TTS??????BTT--------------------------------------------------------B?B???EEEEEGGGGB?TTS--------------------------------------------------------------------------?B?HHHHHHHHHHHHHHHHHHHHH???S-SHHHHH----------------------------HHHHH???EEEEE?HHHHHHHTT??TTSHHHHHHHHHHHHHHHHHHHHHHHHHH-H-HT???G-------------------GG--TTSTTTTT---??GGGGGT??----------------------??T---TS-?--------------------------------------------------------------------------------------------HHHHHHHHHHH-??S?S??B?????TTHHH--HT-T??STT???S?SEEEEEETTEE------EEEE?HHHHHHHHHTT?-----------??HHHHHHHHHTT-------------------T??SS?T-TS?HHHHHH--T?-?-ST-------TS---?HHHHHHHHHHHHTT?SS?????EE?----------------S--S?--?HHHHHHHHHHHHHHT?SEEES?E 3O0Q|A PF02868.10_Peptidase_M4_C_seed 113 269 !Q:1,3|27,39|41,43|47,58|67,74|78,79|81,84|90,90|94,103|106,107|112,119|121,140|145,149|170,170|172,191|199,202|217,217|219,220|223,228|244,246|248,248|251,253|268,268 Q:0,0|4,26|40,40|44,46|59,66|75,77|80,80|85,89|91,93|104,105|108,111|120,120|141,144|150,169|171,171|192,198|203,216|218,218|221,222|229,243|247,247|249,250|254,267 T???SSHHHHHHHHHHHHHHHHHHHHH-------------T---TSS?----------?SEESTTTB?-------TTS?-S--??SEESS?GGG----------GT??SSGG--------G?------??-----------SSHH-----HHHHHHHHHHHHHHHHHHHH?E--------------------EETTEEE????HHHHHHHHHHHHHH-T??TT?----?HHHHHHHHHHHHHHH---H?TT?--HHHHHHHHHHHHTT? 3T8G|A PF02870.10_Methyltransf_1N_seed 11 92 !Q:0,1|18,18|21,22|29,44|46,46|50,50|54,57|71,71|79,84|86,86 Q:2,17|19,20|23,28|45,45|47,49|51,53|58,70|72,78|85,85|87,91 ??EEEEEEETTEEEEEEE?SS?-EEEEEE????????????????B?STT?SHH----HHHHHHHHHHHHH?TTGGGTS--????B?SHHHH 1SFE|A PF02872.13_5_nucleotid_C_seed 119 385 !Q:3,9|14,35|37,39|47,48|50,53|66,78|84,113|120,120|122,122|124,153|155,161|164,164|166,168|176,176|180,180|182,184|186,193|203,203|212,231|240,240|243,243|245,256|260,268|270,270|274,274|277,277|282,282|284,299|302,302|309,320|328,331|333,336|341,342|350,356|358,358|361,364|370,373|376,381 Q:0,2|10,13|36,36|40,46|49,49|54,65|79,83|114,119|121,121|123,123|154,154|162,163|165,165|169,175|177,179|181,181|185,185|194,202|204,211|232,239|241,242|244,244|257,259|269,269|271,273|275,276|278,281|283,283|300,301|303,308|321,327|332,332|337,340|343,349|357,357|359,360|365,369|374,375|382,384 EEE-------EESS--?-------------------B???HHHHTTS??H----HHHHHHHHHHHH-------------TGGGT?---------------?-------------EEEEEG-G-G?--------??--?----------------B------?SE-E---EEHHHHH-HHS?S?-?E--------EEEEEEEHH-HHHHHHHH--------------------HHTTGGGT?TT?E------------EEE---------S-EEE-EE-ETTS?T----------------TS?EEEEEE------------EETTEEE----E?--?TTSE--EEEEEEH-------H-HH----TTGGG--?-HH------HHT 1HP1|A PF02873.11_MurB_C_seed 13 140 !Q:15,16|18,19|27,28|33,35|38,38|47,50|54,58|61,61|65,65|68,69|79,80|83,83|90,92|94,94|104,104|107,108|128,132|134,134 Q:0,14|17,17|20,26|29,32|36,37|39,46|51,53|59,60|62,64|66,67|70,78|81,82|84,89|93,93|95,103|105,106|109,127|133,133|135,139 HHHHHHHHHHHHHHH--S??TTTSEEE--EESB???EE?HHHHHHHH----TTS?????EE?TTS?EE??HHHHHHHTT?-TT?EETTEE---E?SSSTTEEEE?SS??HHHHHHHHHHHHHHHHHHH?????B?SEEEE 1MBT|A PF02874.18_ATP-synt_ab_N_seed 196 84 !Q:15,15|17,20|29,30|32,33|36,36|39,42|45,45|48,48|50,50|68,69|72,73|75,75|77,77 Q:0,14|16,16|21,28|31,31|34,35|37,38|43,44|46,47|49,49|51,67|70,71|74,74|76,76|78,83 EEEEETTEEEEEEST-T????TTEEEEEE--E??SS-TT???-EE-EE-E-EEEEEEETTEEEEEESS??TT??T-T?EEEEEE 3OAA|A PF02875.16_Mur_ligase_C_seed 50 117 !Q:0,0|2,2|9,19|23,23|29,32|48,61|64,64|70,72|75,77|79,79|94,94|97,97|101,102|104,106|110,111 Q:1,1|3,8|20,22|24,28|33,47|62,63|65,69|73,74|78,78|80,93|95,96|98,100|103,103|107,109|112,116 ?T-TSSEEE??---------TTS?EEEEE-???SHHHHHHHHHHHHHT-------------?SS?EEEEE???SS---S?STHHHHHHHHHHHH?SE-EEE??S?-?BTS?-HHHHH 3PYZ|A PF02876.12_Stap_Strp_tox_C_seed 41 139 !Q:1,6|8,10|23,27|52,53|57,57|62,62|65,67|71,71|73,73|80,80|92,93|95,96|103,104|107,109|122,123|131,131 Q:0,0|7,7|11,22|28,51|54,56|58,61|63,64|68,70|72,72|74,79|81,91|94,94|97,102|105,106|110,121|124,130|132,138 E------E??-EEEEETTEEEEE?---?TTSEEEESEEEHHHHHHHHHHHHH--HHH?TTSS?SS???GGG?S?STTSSS?SEEEEEEEESS--S??EEEETT??TT---SSHHHHGGGGTT??EEETTSE-EEEEEEE 3EA6|A PF02877.9_PARP_reg_seed 35 163 !Q:0,2|4,4|16,16|30,30|35,35|39,40|60,74|76,78|85,90|100,100|102,107|110,115|117,118|146,148|150,152|155,155 Q:3,3|5,15|17,29|31,34|36,38|41,59|75,75|79,84|91,99|101,101|108,109|116,116|119,145|149,149|153,154|156,162 ???S?HHHHHHHHHHT?HHHHHHHHHHHTB?TTTS?TTT??HHHHHHHHHHHHHHHHHHH---------------T???HHHHHH------HHHHHHHHS?B???---SS???--?S??HHHHHHHHHHHHHHHHHHHHHHHTTSS???S---SS?HHHHHHH 1A26|A PF02878.11_PGM_PMM_I_seed 89 170 !Q:0,0|3,3|14,14|17,22|24,24|43,47|49,49|52,52|59,59|61,61|80,80|87,92|94,95|106,107|110,116|123,124|128,128|134,137|142,142|145,145|149,150|154,154|166,169 Q:1,2|4,13|15,16|23,23|25,42|48,48|50,51|53,58|60,60|62,79|81,86|93,93|96,105|108,109|117,122|125,127|129,133|138,141|143,144|146,148|151,153|155,165 ?TT?BTTBEEEEBT-TT------B?HHHHHHHHHHHHHHHHHT-----T?SS?EEEEEE?S?TTHHHHHHHHHHHHHHTT?EEEEEE------E??HHHHHHHHHH--TT------?SEEEEE??TTS?TTEEE----EEEE?TT-SSB??HHH-HHHHHHHHHHT???? 1JDY|A PF02879.11_PGM_PMM_II_seed 98 157 !Q:2,5|15,18|26,30|32,39|44,44|60,60|63,77|82,82|85,85|87,88|91,91|94,96|98,98|100,102|104,107|109,109|122,126|128,129|132,133|138,138|142,143|148,152 Q:0,1|6,14|19,25|31,31|40,43|45,59|61,62|78,81|83,84|86,86|89,90|92,93|97,97|99,99|103,103|108,108|110,121|127,127|130,131|134,137|139,141|144,147|153,156 HH----HHHHHHTTS?---HHHHHHH?---?E--------EEEE?TTSGGGGTHHHHHHH-HT?--------------EEEE-ES?S??TT?SS---S?S???T----T-TTHHHHHHHHHH-----T?-SE--EEEE?TTS??EEEE-----ETTS 1JDY|A PF02880.11_PGM_PMM_III_seed 584 206 !Q:0,5|9,9|19,26|31,40|45,52|54,55|63,63|65,65|73,75|77,77|80,82|84,84|87,87|90,90|100,100|105,109|111,120|124,124|127,127|134,134|137,142|144,148|150,155|169,177|180,181|183,190|196,196|200,205 Q:6,8|10,18|27,30|41,44|53,53|56,62|64,64|66,72|76,76|78,79|83,83|85,86|88,89|91,99|101,104|110,110|121,123|125,126|128,133|135,136|143,143|149,149|156,168|178,179|182,182|191,195|197,199 ?-----HHH-HHHHHHHHH--------HHTT---------?SGGG--------E--EEEETTS?H-HHHHHHH---H-TT?--E-EE-EE?SSHHHHHHH-HHHH-----T-------?-?EEE?TT-SBEEET-TT-----?S-----S----??HHHHHHHHHHHHH---------HH--T--?----?HHHHH-TTS??---? 1JDY|A PF02881.14_SRP54_N_seed 189 99 !Q:1,1|13,18|20,23|28,29|45,46|62,65|69,81|85,85 Q:0,0|2,12|19,19|24,27|30,44|47,61|66,68|82,84|86,98 H-HHHHHHHHHHS???---S??-?HHHH--HHHHHHHHHHHHHHT??HHHHHHHHHHHHHHH----SSS----------???SSS?TTTTTHHHHHHHH 2Q9B|A PF02882.14_THF_DHG_CYH_C_seed 91 205 !Q:11,18|21,22|35,35|38,43|46,46|52,54|68,76|78,85|87,87|93,93|96,99|101,101|109,109|115,115|117,118|121,121|123,123|128,131|134,134|139,141|144,154|158,159|162,162|165,165|173,174|178,179 Q:0,10|19,20|23,34|36,37|44,45|47,51|55,67|77,77|86,86|88,92|94,95|100,100|102,108|110,114|116,116|119,120|122,122|124,127|132,133|135,138|142,143|155,157|160,161|163,164|166,172|175,177|180,204 SHHHHHHHHTT--??----SS??HHHHHHHHHHHH-TT??---?TT?EEEEE???TTTHHHHHHHHHT---------T--------T?EEEEE?SS?---S?HHHHHHH?SEEEE?S??TT?B?TTTS---?TT?EEEE???EE?----------TTS?-EE?SB?HHHHHHH-?SEE??SSSSSHHHHHHHHHHHHHHHHHHTT 3L07|A PF02883.15_Alpha_adaptinC2_seed 102 155 !Q:0,1|19,27|30,30|43,47|51,51|59,60|63,73|76,76|81,84|86,86|88,88|90,90|93,97|99,101|110,116|119,123|134,136|139,139|143,144|150,154 Q:2,18|28,29|31,42|48,50|52,58|61,62|74,75|77,80|85,85|87,87|89,89|91,92|98,98|102,109|117,118|124,133|137,138|140,142|145,149 ??EEEEEETTEEEEEEEEE--------?SS?TTEEEEEEEEEE---?-SSS?BEEEEEE--EE??---------TT?EEEE???-S?S?B?GG-----G???EEEEEEEE?------TT?????EEEEEEEEET---TE-EEE--EEEEE??-?? 1KYD|A PF02884.12_Lyase_8_C_seed 29 102 !Q:0,0|18,24|33,33|37,42|47,49|67,67|74,74|77,81|87,87|89,89|97,97 Q:1,17|25,32|34,36|43,46|50,66|68,73|75,76|82,86|88,88|90,96|98,101 ?EEEEESSSEEEEEEGGG-------TEEEEEES-SSE------EETT---EEESSSEEEEEEEETTE-EEEEEE?TT?????EEEEE?S?EEEEEEE?TTEE 2E24|A PF02885.12_Glycos_trans_3N_seed 135 87 !Q:6,6|13,20|35,35|37,48|63,68|80,81|86,86 Q:0,5|7,12|21,34|36,36|49,62|69,79|82,85 HHHHHH-HHHHTT----????HHHHHHHHHHHHTT?S?-----------HHHHHHHHHHHHHH?---??HHHHHHHHHHH--HHTS? 1OTP|A PF02886.12_LBP_BPI_CETP_C_seed 10 269 !Q:7,18|26,29|32,44|69,69|75,75|80,80|83,83|85,89|93,97|104,104|112,112|114,114|125,126|134,134|140,140|150,152|156,157|168,169|188,190|192,193|200,203|211,211|231,231|234,238|244,245|250,252 Q:0,6|19,25|30,31|45,68|70,74|76,79|81,82|84,84|90,92|98,103|105,111|113,113|115,124|127,133|135,139|141,149|153,155|158,167|170,187|191,191|194,199|204,210|212,230|232,233|239,243|246,249|253,268 SEEEEEE?------?----EEEESSS????SS????????--???SSSEEEEEEHHHHHHHHHHHHHTT?SEEEE?GGGS?SS?S??---SBH-----HHHTTT?TTHHHHS?S?BEEEEEEESS??EEEEETT-EEEEE?EEEEEEEEE?--TTS-?EEEEEEEEEE??EEEEEEEETTEEEEEEEE???B??EEEETT????GGGGHHH-HHHHHHHHHHHHHHHHHHH?EE????-TTEEE--EEEE---EEEETTEEEEEEEEEE 2OBD|A PF02887.11_PK_C_seed 173 203 !Q:2,4|17,20|23,24|31,31|44,45|47,47|49,52|62,77|84,84|92,114|116,118|120,125|127,135|144,144|148,162|168,171|174,176|183,184|187,187|190,196 Q:0,1|5,16|21,22|25,30|32,43|46,46|48,48|53,61|78,83|85,91|115,115|119,119|126,126|136,143|145,147|163,167|172,173|177,182|185,186|188,189|197,202 HH---HHHHHHHHHHHH----TT-?SEEEEE?SSSHHHHHHHHT??S-S?---EEEEESSHH----------------HHHHGG-GSTTEEE-----------------------E---E?????-S---------HHHHHHHH-HHH---------------HHHHT?-??TT?--EEEEEE?-SS?SS??--???EEEEEE 3EOE|A PF02888.11_CaMBD_seed 5 84 !Q:0,1|23,26|32,32|35,36|83,83 Q:2,22|27,31|33,34|37,82 ??HHHHHHHHHHHHHHHHHHHHH----HHHHS?SS??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS? 3SJQ|C PF02889.11_Sec63_seed 133 661 !Q:1,1|7,10|16,27|37,40|42,43|45,46|48,50|54,64|67,72|78,78|83,87|89,92|104,106|109,113|116,119|121,141|143,144|150,154|167,180|186,201|212,212|222,222|224,228|233,240|258,272|275,276|278,279|282,290|293,293|298,321|323,323|325,325|329,332|335,338|343,345|348,352|358,361|364,372|378,384|389,392|394,399|411,413|416,418|422,422|429,429|433,434|436,464|474,474|476,478|480,513|519,530|540,543|547,547|558,562|565,578|581,592|596,596|599,617|624,626|629,634|638,638|647,647|651,652|660,660 Q:0,0|2,6|11,15|28,36|41,41|44,44|47,47|51,53|65,66|73,77|79,82|88,88|93,103|107,108|114,115|120,120|142,142|145,149|155,166|181,185|202,211|213,221|223,223|229,232|241,257|273,274|277,277|280,281|291,292|294,297|322,322|324,324|326,328|333,334|339,342|346,347|353,357|362,363|373,377|385,388|393,393|400,410|414,415|419,421|423,428|430,432|435,435|465,473|475,475|479,479|514,518|531,539|544,546|548,557|563,564|579,580|593,595|597,598|618,623|627,628|635,637|639,646|648,650|653,659 E?HHHHH----HHHHT----------??HHHHHHHHH----H??T--T?-?HHH-----------HH------HHHHT?GGGT-----T????GGGHHHHHHHH---HH-----SS----S??-----------------?-S??SSHHH-----HHHHHHHHHHTT------?-????--HHHHH----------------HHHHHHHHHH-HHHHHHHHH-H-----HTTT--------BHHHHHHHHHHHHHHHH---------------TS?-T--TS--------?GG-GGST------------------------T-S?HHH----HH----HHHH---TT-?--?GGGGT----TS--------?HHHHH-------HHHT-?--G------GGHHHHHHHHT---TS-??EEE-EEEEEE?SSS--E-----------------------------EEEEEEEEE?S???T----------------------------------TTTTT------------EEEEEEEEE--?-TTS?BEEEEEEEEE-----ES--------------TT------------TTS?EE-------------------EEEEEE??-SS??----SEE-EEEEEESS-STT?-EEEEEEE? 4F91|B PF02891.15_zf-MIZ_seed 36 56 !Q:4,4|11,11|14,15|22,23|26,27|41,47|49,49|53,54 Q:0,3|5,10|12,13|16,21|24,25|28,40|48,48|50,52|55,55 EESB?TTTSSB?SS--EEEETT??SS??EEHHHHHHHHHHS??----?B?TTT??B 4FO9|A PF02892.10_zf-BED_seed 41 66 !Q:0,1|7,11|15,15|21,22|31,42|53,60|64,64 Q:2,6|12,14|16,20|23,30|43,52|61,63|65,65 ??TTSSS?????SSS?GGGSS??EETTTTEE????--------SSTHHHHHHH--------HHS?H 2CT5|A PF02893.15_GRAM_seed 33 107 !Q:0,15|17,17|19,20|27,27|39,56|78,78|80,90 Q:16,16|18,18|21,26|28,38|57,77|79,79|91,106 ????-????------?T-T??EEEEEE-EEEEEETTTEE------------------EEEEEEEESSEEEEEESSSSS?E-----------EEEEEGGGEEEEEEES 1M7R|A PF02894.12_GFO_IDH_MocA_C_seed 37 151 !Q:8,8|10,10|18,18|22,22|24,25|37,37|39,44|48,48|67,68|75,77|80,82|84,85|87,87|92,92|98,114|122,122|128,131|136,136|140,141 Q:0,7|9,9|11,17|19,21|23,23|26,36|38,38|45,47|49,66|69,74|78,79|83,83|86,86|88,91|93,97|115,121|123,127|132,135|137,139|142,150 HHHHHTTT-T?SEEEEEE-EEE?B??HHHHHTSTTTT?T------TTT?STTTTTTHHHHHHHHHHH??EEEEEE---EE---E??S?SSSS?SEEEE-----------------EEEETTS?EEEEE----EESB?SSS??EEEEEEEET 3FHL|A PF02895.9_H-kinase_dim_seed 148 155 !Q:0,1|4,4|31,32|37,104|107,116|126,129|131,141|143,143 Q:2,3|5,30|33,36|105,106|117,125|130,130|142,142|144,154 ??EE-EEEHHHHHHHHHHHHHHHHHHHHHHH--TTSS??-----------------------------------------------------------------?HH----------HHHHHHHHH----H-----------H-HHHHHHHHHHH 1B3Q|A PF02896.13_PEP-utilizers_C_seed 17 380 !Q:0,2|4,4|17,18|25,25|39,40|54,55|68,68|105,107|109,109|112,113|117,119|121,121|133,137|139,141|153,154|156,156|162,162|171,172|189,191|197,197|199,201|208,208|210,211|219,219|235,235|238,243|250,250|265,266|272,272|283,284|289,289|302,302|305,305|310,311|333,333|344,344|357,357|363,363|379,379 Q:3,3|5,16|19,24|26,38|41,53|56,67|69,104|108,108|110,111|114,116|120,120|122,132|138,138|142,152|155,155|157,161|163,170|173,188|192,196|198,198|202,207|209,209|212,218|220,234|236,237|244,249|251,264|267,271|273,282|285,288|290,301|303,304|306,309|312,332|334,343|345,356|358,362|364,378 ???S?HHHHHHHHHHHH??SEEEEE?SSHHHHHHHHHTT??SEEEEEHHHHHTT?-HHHHHHHHHHHH?SSHHHHHHHHHHHHHHHHHHHHHHHHHTTTSEEEEE???S?GG--GGS??-S?HHHHHHHHHHH-----H???HHHHHHHHHHH??S?GGGSS?THHHHHHS--HHHHHHHHHHHHHHHH---HHHTT-T???EEEEEE?S??SHHHHHH-HHHHHHHHHHHHHHH-HT?-????EEEEEE?SHHHHHTHHHHTTT-?SEEEE?HHHHHHHHHT??TTTG-GGTHHHHHHTTS?SS?TTTS??TTTHHHHHHHHHHHHHHHSTT?EEEEESGGGG-SHHHHHHHHHTT?SEEEE?GGGHHHHHHHHHHTT? 1VBG|A PF02897.10_Peptidase_S9_N_seed 30 521 !Q:0,5|8,8|17,22|25,25|32,32|35,39|62,62|77,77|79,79|82,84|97,97|100,100|103,103|112,117|120,134|139,139|144,144|148,151|160,160|175,175|177,177|189,214|229,229|233,233|244,248|251,252|255,256|258,265|275,275|279,279|281,281|285,286|289,289|292,293|300,300|312,312|317,318|331,336|339,339|342,344|349,349|354,354|362,368|377,383|386,386|389,389|399,399|404,404|407,413|416,418|421,421|453,464|466,467|473,475|484,485|488,488|497,497|500,502|514,516 Q:6,7|9,16|23,24|26,31|33,34|40,61|63,76|78,78|80,81|85,96|98,99|101,102|104,111|118,119|135,138|140,143|145,147|152,159|161,174|176,176|178,188|215,228|230,232|234,243|249,250|253,254|257,257|266,274|276,278|280,280|282,284|287,288|290,291|294,299|301,311|313,316|319,330|337,338|340,341|345,348|350,353|355,361|369,376|384,385|387,388|390,398|400,403|405,406|414,415|419,420|422,452|465,465|468,472|476,483|486,487|489,496|498,499|503,513|517,520 ??????TT?EEEETTEE------EE?TTGGGG?TT-----SHHHHHHHHHHHHHHHHHHHSS-THHHHHHHHHHHHT?S?EE???EEETTEEEEEEE?SS?SS?EEEEESST------TS??-------------EEEE?GGGG?SSS---?EEEEEEEE?TTSSEEEEEEEETT?S?EEEEEEETTTT--------------------------EEEEEEEEEEEEEE-EEE?TTSSEEEEEE???-?SS??SS--S????????EEEEEETTS?GGG?E-EEE??TT?TT-?EEEEEE?TTSSEEEEEEE?SSSS??EEEEEEGGGSTT------SS?SS???EEEE?SSSS?EEEEEEE-------TTEEEEEE?------TT?TT?EEEEEETTB?SGGG?EE-------EE???SS?EEEEEEEETTTEEEEEEEETTEEEEEEEETT------------T??EEEEE???SSEEEEEE??TT?SEEEEEEE?SS???EEEEEETTSSS???EEEE 1E5T|A PF02898.10_NO_synthase_seed 8 374 !Q:0,4|25,25|48,51|66,66|69,69|77,78|83,83|86,87|109,111|116,119|125,126|129,129|135,135|137,137|141,141|149,149|164,169|172,172|174,175|180,180|183,185|189,192|196,197|201,203|206,206|213,214|219,220|223,223|225,225|236,238|241,242|260,261|271,273|275,275|279,279|301,302|305,305|326,330|336,336|349,351|353,355|361,365|370,373 Q:5,24|26,47|52,65|67,68|70,76|79,82|84,85|88,108|112,115|120,124|127,128|130,134|136,136|138,140|142,148|150,163|170,171|173,173|176,179|181,182|186,188|193,195|198,200|204,205|207,212|215,218|221,222|224,224|226,235|239,240|243,259|262,270|274,274|276,278|280,300|303,304|306,325|331,335|337,348|352,352|356,360|366,369 ?????HHHHHHHHHHHHHHHHHHTT?TTSHHHHHHHHHHHHHHHHHSS????HHHHHHHHHHHHHT?TT?TTGGGTT??EEEE?TT??SHHHHHHHHHHHHHHHHGGGS???EEEE????SSSSS??EE?SSBSS?B?EEE?TTSSEEE?GGGHHHHHHHHHTT??????TT?B??EEEE?TT???EEE?-??GGG??EEE???SS?GGGGGG??EEES??EE?S?EEEETTEEES???EE??EEHHHHHTHHHHSTTTT??HHHHHHHTT???S?GGG?HHHHHHHHHHHHHHHHHHHTT??EE?HHHHHHHHHHHHHHHHHHHS?????HHHHS?SSSGGGSTTTTB???B???SSEEE??-??GGGT???? 3EAI|A PF02899.12_Phage_int_SAM_1_seed 37 108 !Q:3,4|14,14|16,16|37,40|43,44|48,52|57,59|61,61|67,84|88,89|101,102 Q:0,2|5,13|15,15|17,36|41,42|45,47|53,56|60,60|62,66|85,87|90,100|103,107 HHH--HHHHHHHTT?S?HHHHHHHHHHHHHHHHHHHH----TS??TTT?---?HHHH---H-HHHHS?????--------?????HHH--HHHHHHHHHHH--HHHTT 3NRW|A PF02900.13_LigB_seed 47 422 !Q:0,0|6,12|15,21|26,31|34,60|66,67|69,77|79,83|96,99|103,103|105,106|109,151|153,158|160,160|172,173|177,177|181,188|192,196|209,216|218,219|221,221|230,234|237,237|253,258|269,269|272,273|277,278|282,291|293,325|340,345|347,347|351,351|361,361|367,367|383,384|386,393|396,396|398,399|401,401|403,405|413,417|421,421 Q:1,5|13,14|22,25|32,33|61,65|68,68|78,78|84,95|100,102|104,104|107,108|152,152|159,159|161,171|174,176|178,180|189,191|197,208|217,217|220,220|222,229|235,236|238,252|259,268|270,271|274,276|279,281|292,292|326,339|346,346|348,350|352,360|362,366|368,382|385,385|394,395|397,397|400,400|402,402|406,412|418,420 ?EEEEE???????SS?-----?HHHH------HH---------------------------HHHHH--H---------S?--??SEEEEEEEEEEE----SSE-E--EE????--------------??????--------??--???????S??????B?HHHHHHHHHHH--TTS?EEE--------ESS?????HHHHHHHHHHST--------T??S?EEEEEEET-----TS?HHHHHHHHHHHGGGG------GGTEEEEEEE?SS??TTS??SSS???-----??H---------------------------------HHHHHHHHHHTTTT?----?S?GGG?TTTSGGGST-THHHH?SSSTTTHHHHHHHHT??S--------SS?E--E?S???EETTTEE???--EEE? 3VSI|A PF02901.10_PFL_seed 129 1050 !Q:3,4|6,8|14,19|21,22|26,26|32,36|38,38|42,47|67,67|69,74|77,77|82,83|88,97|102,114|116,122|126,126|129,131|133,133|143,147|151,151|155,161|170,201|203,207|217,229|232,233|242,243|247,253|263,271|273,273|279,285|291,291|294,294|300,306|318,346|350,352|372,376|392,394|397,400|413,413|421,422|424,424|426,429|432,432|446,446|450,452|454,454|458,462|477,482|488,504|507,507|509,509|511,514|520,520|522,526|530,531|533,535|547,548|551,553|555,555|563,564|568,572|586,587|589,591|602,633|637,637|639,641|644,644|652,653|655,667|671,675|682,684|691,692|705,705|708,710|712,719|721,721|723,739|741,741|744,746|781,782|786,787|792,795|798,798|807,826|828,828|842,851|859,864|868,885|893,977|979,985|989,995|1012,1012|1018,1020|1022,1023|1025,1030|1032,1032|1039,1040|1046,1046 Q:0,2|5,5|9,13|20,20|23,25|27,31|37,37|39,41|48,66|68,68|75,76|78,81|84,87|98,101|115,115|123,125|127,128|132,132|134,142|148,150|152,154|162,169|202,202|208,216|230,231|234,241|244,246|254,262|272,272|274,278|286,290|292,293|295,299|307,317|347,349|353,371|377,391|395,396|401,412|414,420|423,423|425,425|430,431|433,445|447,449|453,453|455,457|463,476|483,487|505,506|508,508|510,510|515,519|521,521|527,529|532,532|536,546|549,550|554,554|556,562|565,567|573,585|588,588|592,601|634,636|638,638|642,643|645,651|654,654|668,670|676,681|685,690|693,704|706,707|711,711|720,720|722,722|740,740|742,743|747,780|783,785|788,791|796,797|799,806|827,827|829,841|852,858|865,867|886,892|978,978|986,988|996,1011|1013,1017|1021,1021|1024,1024|1031,1031|1033,1038|1041,1045|1047,1049 HTT--T???SGGGT------S??HHH-HHHHH?????S?GGG?-????HHHHHHHHHHHHHHHHHHH-H------TS?SEEE--EEEE??--------SSSS?---------???S---?---TTT?SS???S-SSSTTEEEE?----GGG?SHH-------HHHHHHHT--------------------------------T???-?HHHHHHHHH-------------TS??HHHHHHHH??HHH-------HHHHHHTSS?--------S?TTSSB???????THHHH-HH?HHHHH-------HHHHHHHHTTH-----------------------------HHH---HHTTTHHHHHHHHHHHHHH-----HHHHHHHHHHHHHTT???SS?-??SHHHHHHHHHHH-HHHHHHH??B-S????BS?HHHHHHHHHHHHH-TTS---S?HHH-----HHHHHHHHHHHHTT??????HHHHH-----------------HS?S-S????EEEEE?B?----TTS-?B???HHHHHHHHHHH--HS???S?SEEEEEE?-TTS?----HHHHHHHHHHHHH--H???EEEEHHHHHH--------------------------------HHT?S--?EE-EETTTEE--E-------------ETT-----TEEEEE---EEEEEH--HHHHHHHHTTTB?TT---T?------?B?S-----?--??-???--?S-SS-??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS??HHH--HTTS---?SS?EEEEEEEE--------------------E?HHHHHHHHHHHHH----------SEEEEEE----?-TTS-----------------?EEEEEEE-------------------------------------------------------------------------------------S-?--???TTS??-----HHHHHHHHHHHHHHHH-HHHTS??-G--G------G?EEEEEE??TTHHH-HHH 2Y8N|A PF02902.14_Peptidase_C48_seed 27 299 !Q:0,3|14,22|33,34|43,64|81,83|87,87|96,96|99,105|113,116|124,162|168,168|171,172|175,182|200,201|210,228|234,238|243,243|259,260|262,264|266,276|288,290 Q:4,13|23,32|35,42|65,80|84,86|88,95|97,98|106,112|117,123|163,167|169,170|173,174|183,199|202,209|229,233|239,242|244,258|261,261|265,265|277,287|291,298 ????HHHHHHHHHH---------HHHTSTTEEE??THHHHHHH----------------------HHTGGGTTTHHHHTTS--?GGG?SEEEEEEE-ET-------TTEEEEE----EEETTTT---------------------------------------EEEEE?TT??SS?-------HHHHHHHHHHHHHHHHH--TTSSSSTT?------------------EEEEE?????SSSS?HHHHHHHHHHHHHTT??S???H-----------HHHHHHHHHHH---HHHHTTTT 2CKG|A PF02903.9_Alpha-amylase_N_seed 38 150 !Q:0,2|6,6|8,9|22,22|29,29|34,34|36,38|44,44|47,47|49,63|69,70|75,75|78,84|88,89|95,96|100,103|110,110|113,113|118,119|121,121|124,129|132,134|136,138|146,149 Q:3,5|7,7|10,21|23,28|30,33|35,35|39,43|45,46|48,48|64,68|71,74|76,77|85,87|90,94|97,99|104,109|111,112|114,117|120,120|122,123|130,131|135,135|139,145 ??-TTT?B??SSGGGEEESSSS?EEEEEB?BTTT?S-??EEEEE?TT?E---------------ETTEE??EEEE?EE????---SSB??EEEEE??GGG-?--EEEEEE?EE-TTEE??B?SS?---??SS???S--?STTSEEE???? 1JI2|A PF02905.9_EBV-NA1_seed 5 148 !Q:0,1|3,4|6,7|10,15|32,38|41,42|53,53|68,68|71,71|74,76|81,84|89,92|95,95|108,108|127,127|142,142|146,147 Q:2,2|5,5|8,9|16,31|39,40|43,52|54,67|69,70|72,73|77,80|85,88|93,94|96,107|109,126|128,141|143,145 ??S??S??TT?????-HHHHHHHHHHHHHHTT???????SS??EEEEEEEEES?HHHHHHHHHHHHHH?TT?EE???EEEE????SSSS????TT?EEEEEEEEEEES?HHHHHHHHHHHHHHHHTS?TTGGGEEEEEEEEE-EEE?? 1VHI|A PF02906.9_Fe_hyd_lg_C_seed 141 546 !Q:0,0|7,7|20,21|24,24|26,27|38,38|41,41|43,43|66,66|69,72|77,89|91,92|96,100|111,111|114,114|120,121|123,124|136,139|145,164|167,175|187,187|196,197|200,200|202,224|228,228|242,253|256,260|262,264|269,278|280,280|282,288|291,292|296,296|298,311|313,321|324,326|340,346|348,348|350,351|353,365|368,368|371,372|374,378|388,390|402,417|419,421|423,423|427,428|431,433|436,436|438,442|444,444|453,454|456,456|466,467|470,486|488,508|510,514|516,524|535,535|539,539|542,543|545,546 Q:1,6|8,19|22,23|25,25|28,37|39,40|42,42|44,65|67,68|73,76|90,90|93,95|101,110|112,113|115,119|122,122|125,135|140,144|165,166|176,186|188,195|198,199|201,201|225,227|229,241|254,255|261,261|265,268|279,279|281,281|289,290|293,295|297,297|312,312|322,323|327,339|347,347|349,349|352,352|366,367|369,370|373,373|379,387|391,401|418,418|422,422|424,426|429,430|434,435|437,437|443,443|445,452|455,455|457,465|468,469|487,487|509,509|515,515|525,534|536,538|540,541|544,544 ?EEEEEE?HHHHHHGGGGGT??TT?S-?HHHHHHHHHH-TT?S-EEEETHHHHHHHHHHHHHHHHH-HH----HHHH???-??---????S--SEE??-??HHHHHHHHHH?GG-GGGGB??B??HHHHHHHHHHH----HHHHH--------------------HT?------?-GGGEEEEEEES?SSHHHHHT-?TT?B?----------------??????BSS?EEEEHHHHHHHHH------------HT-----T??-GGGS??---?????T-T-------SS--SSS?S??------------S---------SB???HHHHHHHHHHHHH-------H-S--S???--?----???EE?TT?-T-----TEEEEEEEE???TTSHHHHHHHH????????????????S???S?EEE??TT???EE-E-----E-EEEEEESH--H-HHHHHHHHH--HH-----------------T---------------------S-----S?-------?SEEEEESSTT?GGG?TT--S?- 3C8Y|A PF02907.10_Peptidase_S29_seed 9 150 !Q:0,0|8,8|11,11|25,25|32,33|42,43|57,58|61,63|65,65|67,68|70,71|78,78|82,82|108,108|111,111|115,115|119,119|141,141|146,149 Q:1,7|9,10|12,24|26,31|34,41|44,56|59,60|64,64|66,66|69,69|72,77|79,81|83,107|109,110|112,114|116,118|120,140|142,145 ?SSEEEEE?SS?EEEEEEBSSEEEE?HHHHTT??EEBSSSEE??SEEETTTTEEEEE??TT???B?B??S??SEEEEE?TTS?EEEEEEEETTEEEEEEEEEHHHHTT?TT?EEE?TTS?EEEEEEEEEEETTEEEEEEEE-EGGG???? 3SV7|A PF02909.12_TetR_C_seed 18 160 !Q:1,3|7,8|37,41|60,61|81,88|94,95|103,118|121,124|131,133|139,139 Q:0,0|4,6|9,36|42,59|62,80|89,93|96,102|119,120|125,130|134,138|140,159 S?-?TTS-?HHHHHHHHHHHHHHHHHTSTTHHHHHTT?-???GGGHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHHHH--------HHHHH--HHHHHHT?????-????--?---HH----HHHHHH---HHHHS?HHHHHHHHHHHHHHHHHHHH 2G7G|A PF02910.15_Succ_DH_flav_C_seed 142 209 !Q:16,16|25,32|39,39|44,44|46,46|48,48|51,56|60,60|86,87|89,89|98,128|131,131|135,135|139,143|148,149|157,157|161,172|176,177|182,186|188,188|191,195|198,208 Q:0,15|17,24|33,38|40,43|45,45|47,47|49,50|57,59|61,85|88,88|90,97|129,130|132,134|136,138|144,147|150,156|158,160|173,175|178,181|187,187|189,190|196,197 HHHHHHHHHHHSSSEE?HHHHHHHH--------HHHHHH-HGGG-G-G-EE?-????STT?HHHHHHHHHHHHHHHHHHHHHHHHH??S?BTTBEESS--??-----------------------????SS?TTS?SSS?????TTTS??EEEEEEE?TTT-?---------?EEE--EEEE?????S?TT-----TS???-??????? 3AE5|A PF02911.13_Formyl_trans_C_seed 130 192 !Q:0,2|8,9|11,11|26,28|30,30|34,35|39,41|44,47|50,56|58,61|64,73|79,85|89,98|100,123|126,128|130,134|142,142|146,146|149,149|151,151|155,160|164,164|168,169|175,176|185,188 Q:3,7|10,10|12,25|29,29|31,33|36,38|42,43|48,49|57,57|62,63|74,78|86,88|99,99|124,125|129,129|135,141|143,145|147,148|150,150|152,154|161,163|165,167|170,174|177,184|189,191 ???HHHHB??T-TSBHHHHHHHHHHT---T-TTT-?EEE---EE----TT-------E----EE----------EEEEE-------EEE-----?????S?-----------------------TT---B-----EEEEETT-EEE-EE?S-BSE------EEE-EEE--EETTS??EEHHHHHH----HSG 1Z7E|A PF02912.13_Phe_tRNA-synt_N_seed 53 74 !Q:0,71 Q:72,73 ?????????????????????????????????-??????????????????????????????????????TT 2IY5|A PF02913.14_FAD-oxidase_C_seed 62 334 !Q:0,1|19,20|30,30|32,34|41,41|52,62|64,64|78,78|82,82|92,92|95,96|114,114|120,145|152,154|162,170|214,216|218,219|231,237|251,267|283,310|323,323|326,327|330,333 Q:2,18|21,29|31,31|35,40|42,51|63,63|65,77|79,81|83,91|93,94|97,113|115,119|146,151|155,161|171,213|217,217|220,230|238,250|268,282|311,322|324,325|328,329 ??SEEEEEEEEESSHHHHH--HHHHHHHHT-T???SEEEEE?HHHHHHHHHS???????????H-HHHHHHHHHTTTS?TTT?EEEEEEEEE?HH--HHHHHHHHHHHHHHHTT?EEEEE-------------------------?STTGGG---SSGGGHH---------HHHHHHHTTTEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHTT---T??EEEEEEEEEEE-------TTEEEEEEEEEEE-------??????????HHHHHHHHHHHHHTT???????????????----?????????HHHHHHHHHHHH?TT??BS???? 3PM9|A PF02914.10_DDE_2_seed 2 221 !Q:0,4|16,17|19,19|22,22|26,26|29,30|41,42|52,53|69,69|78,93|95,95|100,105|119,143|150,150|157,159|161,161|164,165|168,171|177,177|197,201|210,210 Q:5,15|18,18|20,21|23,25|27,28|31,40|43,51|54,68|70,77|94,94|96,99|106,118|144,149|151,156|160,160|162,163|166,167|172,176|178,196|202,209|211,220 ?????TTTEEEEEEEE??S?EE?TTS?EE??EEEEEEETTT??EEEEEEESS??HHHHHHHHHHHHHHH?EESSEEEE????????????????S?TTSS??????HHHHHHHTTEEEE?????????????????????????TTTTTT?GGGTTT???S?SS??GG----GHHHH?EEHHHHHHHHHHHHHHHHH?????STTTTTTS?HHHHHHHHHT 4FCY|A PF02915.12_Rubrerythrin_seed 38 153 !Q:23,25|28,30|60,70|72,73|76,82|84,86|90,92|120,120|128,133 Q:0,22|26,27|31,59|71,71|74,75|83,83|87,89|93,119|121,127|134,152 HHHHHHHHHHHHHHHHHHHHHHS???TT---HHHHHHHHHHHTHHHHHHHHHHHHHHSTT????-----??S??BS???????S???SHH---HHHHHHHHHHHHHHHHHHHHHHHHHTS?SHHHHHH------HHHHHHHHHHHHHHHHHHH 1J30|A PF02916.10_DNA_PPF_seed 11 120 !Q:0,3|17,17|23,23|29,30|34,34|43,44|52,52|54,54|59,59|71,71|74,74|76,80|84,86|95,95|98,98|103,106|111,113|116,119 Q:4,16|18,22|24,28|31,33|35,42|45,51|53,53|55,58|60,70|72,73|75,75|81,83|87,94|96,97|99,102|107,110|114,115 ????HHHHHHHHHHHHH?SSEEE?SEEEE--EEE?TTSSBEEE--EEEEEEE?S?EEES?HHHHHHHHTTS?TT?E-----EEE?--SSSSEEEE?SS?EEEE????GGGS???SS???? 4DE8|A PF02917.9_Pertussis_S1_seed 2 239 !Q:0,2|12,12|20,20|23,23|25,25|28,29|36,39|48,49|58,58|63,63|84,84|96,97|115,115|120,120|140,140|164,166|169,178|181,188|190,192|194,194|211,228|238,238 Q:3,11|13,19|21,22|24,24|26,27|30,35|40,47|50,57|59,62|64,83|85,95|98,114|116,119|121,139|141,163|167,168|179,180|189,189|193,193|195,210|229,237 ???SEEEEEESS?HHHHHHH?EE?S?SB??HHHHHH----TGGGSTTT??BSEEEEES?HHHH-HHHHHHHHHHHHHHHTTTSS?SEEEEEEEEEE??TTEEEHHHHHHHHHHHH?GGGS?HHHHHHHHHHTEEEEESEE?GGGEEEEEEEEEETTTTEEEEEE???SS?????????-SS????????S???S?EEETTTTEEHHHHHHH??????????????????EEEHHHHSS? 1BCP|A PF02918.10_Pertussis_S2S3_seed 3 111 !Q:0,0|3,11|17,17|29,29|47,47|53,53|55,55|73,76|86,87|91,91|94,94|104,105|108,108 Q:1,2|12,16|18,28|30,46|48,52|54,54|56,72|77,85|88,90|92,93|95,103|106,107|109,110 ?EE????????-EEESS?EEEEEEEETTS?EEEEEESSSSEEEEEEE?SSSST-T?TTHHHHHHHHHHHHHHT????EEEEEEEEE??SSS?SS?EEEEEEEEE??TT?TT 1BCP|B PF02919.10_Topoisom_I_N_seed 47 249 !Q:0,2|4,4|7,10|12,20|23,24|33,35|53,53|57,57|77,78|81,93|99,99|111,114|120,124|127,134|143,143|157,157|163,164|166,169|172,175|178,178|183,183|186,189|192,192|194,194|198,199|203,207|209,212|215,218|223,224|227,229|235,236|240,242 Q:3,3|5,6|11,11|21,22|25,32|36,52|54,56|58,76|79,80|94,98|100,110|115,119|125,126|135,142|144,156|158,162|165,165|170,171|176,177|179,182|184,185|190,191|193,193|195,197|200,202|208,208|213,214|219,222|225,226|230,234|237,239|243,248 ???S?EE????B?????????TT??EEETTEEE???HHHHHHHHHHHHTTTSS-GGG?HHHHHHHHHHHHHHHHHTT??TT------???-???GGGEE?HHHHHHHHHHH----HHHTT?????HH--------HHHHHHHH-HHHHHHEEEETTE-EEEEE??B????EE????TT?TTTT?EE????GG-G?EEE??SSS?????S----TT?-??SEEE??TT???SEEEE?-TTT??-EEEEEE 1OIS|A PF02920.10_Integrase_DNA_seed 4 67 !Q:0,4|8,11|14,14|17,17|21,21|28,28|31,32|40,40|45,48|51,56 Q:5,7|12,13|15,16|18,20|22,27|29,30|33,39|41,44|49,50|57,66 ?????SSS????TT?EE?TTS?EEEEEE?TT??EEEEEES?SSTT????TT??????HHHHHHHHHH 1TN9|A PF02921.9_UCR_TM_seed 30 80 !Q:0,1|4,11|13,18|22,22|26,27|31,31|48,48|72,77 Q:2,3|12,12|19,21|23,25|28,30|32,47|49,71|78,79 ??TT?--?????T------TTB?GGG??SSS?THHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHH??----HH 1SQB|E PF02922.13_CBM_48_seed 59 135 !Q:0,1|6,6|9,14|24,24|27,27|40,41|43,47|53,55|58,58|70,74|80,80|83,84|86,87|99,101|104,105|108,109|112,114|117,117|120,124|128,128|130,131|134,134 Q:2,5|7,8|15,23|25,26|28,39|42,42|48,52|56,57|59,69|75,79|81,82|85,85|88,98|102,103|106,107|110,111|115,116|118,119|125,127|129,129|132,133 ??EEEE?TT------SSEEEEEEE?SS?SEEEEEEESSSS--S?--??SEEEE?--EE?STTEEEEEEEH-----HHHHH-TT??S??EEEEEEEBTTB???TT??TT??TT???SS?TT?????TTS?B??TT? 2BXY|A PF02923.10_BamHI_seed 3 168 !Q:0,0|8,8|18,18|34,36|41,41|48,48|53,53|55,56|72,73|78,79|87,91|112,113|135,135|144,144|156,157 Q:1,7|9,17|19,33|37,40|42,47|49,52|54,54|57,71|74,77|80,86|92,111|114,134|136,143|145,155|158,167 ?EEEEEEE?HHHHHHHHH?HHHHHHHHHHHHHHH???BSTT?SSBEEE?SSTT?B??GGGGHHHHHHHHHTT??EEEE??HHHHTTS?????EEEEEEEEETTEEEEEEEEE??SBHHHHHHHHHHHHHHHHTTS?SEEEEEEE?HHHHTTBSTTB??HHHHGGGGGG 3BAM|A PF02924.9_HDPD_seed 74 242 !Q:0,12|15,15|19,21|29,35|37,37|39,39|42,42|46,50|52,52|55,57|59,159|163,173|179,179|187,187|189,189|191,195|201,203|209,210|217,219|222,223|225,225|239,239 Q:13,14|16,18|22,28|36,36|38,38|40,41|43,45|51,51|53,54|58,58|160,162|174,178|180,186|188,188|190,190|196,200|204,208|211,216|220,221|224,224|226,238|240,241 ???????-?????SS?SSS??-EEEEEEB???----S?B?SS?EEE-----E?TT---T------------------------------------------------------------------------------------------------??---EEE?---------?SSSTT?EEEEESS?B?S?---?SEEEE---EEEEE--EETTTS???TT??H-HHHHTTTTTSEEE-EE 1VD0|A PF02925.11_gpD_seed 2 141 !Q:0,1|21,27|36,36|39,41|64,70|84,84|98,98|100,100|108,113|128,128|131,134|138,140 Q:2,20|28,35|37,38|42,63|71,83|85,97|99,99|101,107|114,127|129,130|135,137 ??HHHHHHHHHHHHHHHHHHH???????HHHHHHHH?SS???SSTHHHHHHHHHHHHSHHHHHS???????BHHHHHHHHHHHS?HHHHHHHHHHTTT?B?HHHHHHT??????HHHHHHHHHHHHHS?TT????STT??? 1TX9|A PF02926.12_THUMP_seed 48 192 !Q:11,13|27,27|29,35|48,57|66,76|81,82|103,103|106,108|120,120|122,136|139,139|157,164|167,167|171,171|183,183|190,191 Q:0,10|14,26|28,28|36,47|58,65|77,80|83,102|104,105|109,119|121,121|137,138|140,156|165,166|168,170|172,182|184,189 HHHHHHHHHTT???SEEEEETTEEEEE?S------?HHHHHHHHTTST----------TEEEEEEE-----------EEEE??HHHHHHHHHHHHHHHHHHHT?SS?--EEEEEEEESSS?S---------------SS?HHHHHHHHHHHHHHHSS-------?EE?SSS?SEEEEEEEETT-EEEEES?? 3TMA|A PF02927.9_CelD_N_seed 42 127 !Q:0,11|15,16|21,21|25,26|34,34|37,43|49,49|53,53|55,55|61,61|65,65|67,94|101,101|104,108|116,118|121,125 Q:12,14|17,20|22,24|27,33|35,36|44,48|50,52|54,54|56,60|62,64|66,66|95,100|102,103|109,115|119,120|126,126 ?????????---SEE??SSEE?TTS??EEEEEES?SS-----??EEEEE?TTS?E-EEEEE?EEE-E????---------------------???EEEEEE?TT??-??EEEEEEE?--TT?--??T 3RX8|A PF02929.12_Bgal_small_N_seed 21 333 !Q:3,5|16,16|23,23|29,29|33,34|40,45|52,53|57,58|66,77|86,86|100,113|129,129|131,131|133,133|147,147|157,157|160,163|165,168|179,182|194,195|200,200|203,203|216,219|222,223|225,227|237,249|258,262|269,269|272,272|279,280|286,289|292,292|301,305|307,307|311,314|319,320|322,322|332,332 Q:0,2|6,15|17,22|24,28|30,32|35,39|46,51|54,56|59,65|78,85|87,99|114,128|130,130|132,132|134,146|148,156|158,159|164,164|169,178|183,193|196,199|201,202|204,215|220,221|224,224|228,236|250,257|263,268|270,271|273,278|281,285|290,291|293,300|306,306|308,310|315,318|321,321|323,331 EET---TEEEEEETTT?SEEEEE-ETTEE?EEE--EEEEE??????HHHHTT??SSS??TTSHHHH------------HHHHTGGG?EEEEEEEEEEEET--------------TEEEEEEEEEEESSS?E-E-EEEEEEEEEETTS?EEEEEEEEE?TT----S??-?SEEEEEEEES??-?SEEEEEEEESS??BTTB?TT?EEEEEEEEGGGG????SS??S???EEEEEEEEE-------------TTEEEEEE-----EEEEEE-SS?HHHHHH-?SSGGG????SS?EEEEEEEE?????S?SSS????TTTS??S-SEEEEEEEE? 1HN1|A PF02931.18_Neur_chan_LBD_seed 92 300 !Q:11,16|19,27|32,38|71,72|75,78|82,85|92,92|98,103|106,109|115,122|124,125|128,129|132,132|137,137|139,146|148,149|153,154|157,157|163,166|174,175|184,195|198,199|201,207|214,247|252,253|256,256|259,261|265,266|272,274|280,286|295,299 Q:0,10|17,18|28,31|39,70|73,74|79,81|86,91|93,97|104,105|110,114|123,123|126,127|130,131|133,136|138,138|147,147|150,152|155,156|158,162|167,173|176,183|196,197|200,200|208,213|248,251|254,255|257,258|262,264|267,271|275,279|287,294 HHHHHHHHHHT----??SS????----?SSSS-----?-EEEEEEEEEEEEEEEETTTTEEEEEEEEEEEE??TT????TTT----HHHHSS?EEEGG------GS????EEETT-----???S??TT?-SS?EEEE?S--------S??EEE??EE-EEEEE????GGGSSSS??EEEEEEEE------------SS??T-------TTEEEE???----------------------------???SGGG??TT?SS???EEE--EEEEE???TTSSS??----?EEEEEEEE????? 2WN9|A PF02932.11_Neur_chan_memb_seed 50 478 !Q:21,21|23,23|49,49|56,59|86,454 Q:0,20|22,22|24,48|50,55|60,85|455,477 HHHHHHHHHHHHHHHHHHHHH?G-GGHHHHHHHHHHHHHHHHHHHHHHH-HHHHHS????TTHHHHHHHHHHHHHHHHHHHHHHHT??-??????????????-???????-----????????????????????????????????????------------------------------------------------------------------------------------------------------------------------------------------??????????????????????????????????????????---------------??????------------------------------------------------------------------------------------??????????????????HHHHHHHHHHHHHHHHHHHHHHH 3EI0|A PF02933.12_CDC48_2_seed 103 129 !Q:1,2|4,4|18,18|25,25|28,41|44,46|49,54|56,73|89,101|104,104|107,107|110,110|114,122|125,125|127,127 Q:0,0|3,3|5,17|19,24|26,27|42,43|47,48|55,55|74,88|102,103|105,106|108,109|111,113|123,124|126,126|128,128 S??S?HHHHTHHHHHTTT?EEEETT?EE--------------EE---EE------T------------------TEEEEEEEEEEESSS-------------EE-EE?TT?EEE?-?------SS?B?H 3HU2|A PF02934.10_GatB_N_seed 147 675 !Q:2,3|13,16|19,19|24,24|26,28|31,39|41,41|43,43|45,46|52,54|57,88|106,106|108,108|110,113|116,117|119,119|125,127|130,130|142,146|152,153|157,158|161,181|185,185|187,192|195,257|260,261|270,272|280,313|324,324|332,332|334,337|340,340|348,351|366,369|383,399|403,422|425,431|433,446|453,453|475,615|618,630|643,644|647,655|658,658|662,663|666,667 Q:0,1|4,12|17,18|20,23|25,25|29,30|40,40|42,42|44,44|47,51|55,56|89,105|107,107|109,109|114,115|118,118|120,124|128,129|131,141|147,151|154,156|159,160|182,184|186,186|193,194|258,259|262,269|273,279|314,323|325,331|333,333|338,339|341,347|352,365|370,382|400,402|423,424|432,432|447,452|454,474|616,617|631,642|645,646|656,657|659,661|664,665|668,674 EE--EEEEEEEEE???-SB?SSSS?B??-SS?-----?--S-S?S??TTTTT?--TT??---------------------------??-EEHHHHHHHHHHHHHTT?E-E---?SE--E?EEEEE???TT?TTSEEEEESSS?----SEEEE--EEE--EE--------------------?SSS?E------EE---------------------------------------------------------------EE--EEEEEEEE???EEEEETT----------------------------------EEEEETTSTT?EEEEEEE?T----TB?SHHHHHH----HHHHHHHHHHHHTS????TTTTSEEEEEEEE-----------------EEE--------------------TT?-----?S----------????EEEEEE?SHHHHHHHHHHHHHHHHHHHH---------------------------------------------------------------------------------------------------------------------------------------------TT--?----?-????EEEEETTTTEEE??SS?????????EE?TTS??EE??HHHHHHH 2G5I|B PF02935.11_COX7C_seed 14 89 !Q:0,36|41,49|54,55|58,58|88,88 Q:37,40|50,53|56,57|59,87 ?????-----?????????????-----------???STTT---------SSSS??SS-HHHHHHHHHHHHHHHHHHHHHHHHHHHTT? 1V55|L PF02936.9_COX4_seed 10 145 !Q:0,3|10,15|18,19|21,21|24,24|26,30|43,43|48,48|60,60|63,63|67,67|70,72|101,105|131,131|144,145 Q:4,9|16,17|20,20|22,23|25,25|31,42|44,47|49,59|61,62|64,66|68,69|73,100|106,130|132,143 ????GGGTTS??????TT??S?SS?S?????HHHHHHHHHTTS?GGGS?HHHHHHHHHHH?SS?HHH-HT???SHHHHHHHHHHHHHHHHHHHHHHHHHHT?????GGGSHHHHHHHHHHHHHTTSSTTTT-SGGGEETTTTEE?- 1V55|D PF02937.10_COX6C_seed 8 73 !Q:0,8|10,10|53,54|67,68|71,72 Q:9,9|11,52|55,66|69,70 ?????????B?HHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHT??HHHHHHHHHHTT??SS?? 1V55|I PF02938.9_GAD_seed 24 110 !Q:6,7|21,21|24,25|34,36|44,48|50,50|54,54|64,64|70,72|74,74|87,88|91,92|101,101 Q:0,5|8,20|22,23|26,33|37,43|49,49|51,53|55,63|65,69|73,73|75,86|89,90|93,100|102,109 HHHHHT?-TTEEEEEEEETTG-GG??TTHHHHHH---HHGGGGT?????B?EES?GGGGGGGEE?TTTTT---S?HHHHHHHHHHHT??TT-?EEEEEEEE-HHHHHHHH 1EFW|A PF02939.11_UcrQ_seed 7 81 !Q:4,4|6,9|18,18|23,24|26,27|38,39 Q:0,3|5,5|10,17|19,22|25,25|28,37|40,80 BTTB?S????BSEEEEEE?GGGB??S??TTTSSSSSTT?-TTTTTHHHHHHHHHHHHHHHHHHHHHHHHHTSSTTHHHHHH 1SQB|G PF02940.10_mRNA_triPase_seed 24 385 !Q:0,1|18,29|31,31|49,49|52,56|60,62|65,65|67,67|71,72|74,82|84,84|89,91|107,168|191,215|222,224|228,230|232,235|238,240|253,253|258,300|312,313|316,320|329,330|332,332|343,343|358,362|364,374 Q:2,17|30,30|32,48|50,51|57,59|63,64|66,66|68,70|73,73|83,83|85,88|92,106|169,190|216,221|225,227|231,231|236,237|241,252|254,257|301,311|314,315|321,328|331,331|333,342|344,357|363,363|375,384 ??HHHHHHHHHHHHHHHT------------S?TTTGGGEEEEEEEEEEE?SS----?SSB???SB?S?EEE??T---------T?EEEE???HHHHHHHHHHHHHHH--------------------------------------------------------------TSGGGTTTEEEEEEEEEEEEEE??----------------???????EEEEEE---ESS---S????EE---EEEEEEEEEEEE?TTSS?------------------------------------------EEEEEEEEEEE??SS?----HHHHHTTS??S?EEEEEEEEEE-EGGGTEEEEEEEEE-----E????-??????EEEEEEEEEE 2QY2|A PF02941.10_FeThRed_A_seed 17 78 !Q:2,2|7,7|9,10|14,15|22,22|25,25|27,27|29,29|37,37|45,47|50,50|55,55|58,67|69,69|74,74 Q:0,1|3,6|8,8|11,13|16,21|23,24|26,26|28,28|30,36|38,44|48,49|51,54|56,57|68,68|70,73|75,77 TT?EEEE?S??EES??GGGTTS?EE?T-T?EEEEEEE?SEETTEE???SS?EEEE?SS----------S?EEEE?GGG 2PVO|B PF02942.9_Flu_B_NS1_seed 5 247 !Q:0,12|38,40|66,66|70,72|91,91|100,247 Q:13,37|41,65|67,69|73,90|92,99 ?????????????TTHHHHHHHHHHHHHHHHHHHHHTT???HHHHHHHHHHHHHHHHHHHHHHTTS?GGG???HHHHHHHHHHHHHHHHHT?GGGGGGGG???-------------------------------------------------------------------------------------------------------------------------------------??-----????- 1XEQ|A PF02943.10_FeThRed_B_seed 20 120 !Q:18,18|20,21|44,44|46,46|50,53|55,55|60,60|64,64|70,70|77,84|91,95|98,101|104,105|107,107|109,111 Q:0,17|19,19|22,43|45,45|47,49|54,54|56,59|61,63|65,69|71,76|85,90|96,97|102,103|106,106|108,108|112,119 HHHHHHHHHHHHHHHHTT?B??SSHHHHHHHHHHHHHHHHHHSS?B?TTB??--S?HHHH-HHH?TTBSS?HHHHHH??-----?TTSSSB?----SS?---TT??S?S???HHHHHHHH 2PVO|A PF02945.10_Endonuclease_7_seed 16 131 !Q:0,0|2,3|8,14|20,20|29,30|32,32|35,36|38,40|42,43|50,53|58,61|69,77|83,83|89,89|94,95|101,102|111,111|113,114|120,121 Q:1,1|4,7|15,19|21,28|31,31|33,34|37,37|41,41|44,49|54,57|62,68|78,82|84,88|90,93|96,100|103,110|112,112|115,119|122,130 ?B??TTHH-------HHHHH-HHHHHTTT--B?TT--T?-?B??SSGGGS----EEEE????SSTTTTB---------EEEEE?HHHHH-HHHH--HHHHH--HHHTHHHH-T??HHHHH--HHHHHHHTS 2QNC|A PF02946.9_GTF2I_seed 18 76 !Q:18,18|21,25|32,32|41,42|45,46|49,49|54,54|68,68|73,73|75,75 Q:0,17|19,20|26,31|33,40|43,44|47,48|50,53|55,67|69,72|74,74 HHHHHHHHHHHHHHHHHT?SS?????HHHHHH?SSSEEEES??TT??SS?GGGS?HHHHHHHHHHTTT?EEEE?S? 2DZR|A PF02947.9_Flt3_lig_seed 3 135 !Q:0,5|8,9|11,11|29,29|37,40|64,64|85,90|93,94|121,122|124,125|131,134 Q:6,7|10,10|12,28|30,36|41,63|65,84|91,92|95,120|123,123|126,130 ??????SS??S?SSHHHHHHHHHTTSBTT?EEEEESS????TTTHHHHHHHHHHHHHHHHHHTB?HHHHHHHHHHHHHHGGGGGS??????TT??EEEEEHHHHHHHHHHHHHHHTTTTTT--S??GGGGS???? 1ETE|A PF02951.9_GSH-S_N_seed 155 160 !Q:0,0|6,6|8,8|12,13|17,17|31,31|37,37|44,44|46,50|53,62|72,72|75,75|77,77|80,91|93,95|102,102|109,109|116,122|136,140|143,146|149,149|154,154 Q:1,5|7,7|9,11|14,16|18,30|32,36|38,43|45,45|51,52|63,71|73,74|76,76|78,79|92,92|96,101|103,108|110,115|123,135|141,142|147,148|150,153|155,159 ?EEEEE?S?GGG??TTT?HHHHHHHHHHHTT?EEEEE?GGGEEE-E-----TT----------EEEEEEEEE-EE?S?SS----------??E---EEEEEE-EEEGGG-SSEEEE???????HHHHHHHHHHHHH-----HH----TT?EEES?HHHHH 1GSA|A PF02952.12_Fucose_iso_C_seed 45 182 !Q:2,2|7,8|11,13|18,19|22,22|26,26|29,31|35,36|47,47|52,53|57,57|60,65|70,70|72,73|76,76|93,93|102,105|108,109|119,119|123,123|130,132|135,136|149,149|160,161|170,170|175,176|179,179|181,181 Q:0,1|3,6|9,10|14,17|20,21|23,25|27,28|32,34|37,46|48,51|54,56|58,59|66,69|71,71|74,75|77,92|94,101|106,107|110,118|120,122|124,129|133,134|137,148|150,159|162,169|171,174|177,178|180,180 GG?EEEE??SS???GGGG??EE?TTS?EE???GGG??HHHHHHHHHT?EEEE??TTT?TT?----?EEEE?B??TT?EEEEEEEEEETTTEEE-EEEEEEEE????HH--HHHHHHHHS?TTS?BEEEEE???SS--GGGSSHHHHHHT?SSSEEEEEES??HHHHHHHH-HHHT??EE-E? 3A9T|A PF02953.10_zf-Tim10_DDP_seed 113 79 !Q:0,7|18,20|31,32|34,38|40,41|45,50 Q:8,17|21,30|33,33|39,39|42,44|51,78 ????????TTTTTHHHHH---HHHHHHHHHH??T-----T??SSS??----HHHHHHHHHHHHHHHHHHHHHHHHHHHH 2BSK|A PF02954.14_HTH_8_seed 86 45 !Q:4,5|21,21|29,29|32,33|45,45 Q:0,3|6,20|22,28|30,31|34,44 HHHH--HHHHHHHHHHHHHTS?HHHHHHH-HT??HHHHHHHHHHT- 4FTH|A PF02955.11_GSH-S_ATP_seed 37 192 !Q:4,4|10,13|17,19|25,25|39,40|45,45|48,49|54,54|58,58|61,62|78,79|81,81|87,88|94,94|106,106|109,113|119,121|124,124|126,128|133,133|140,141|160,161|177,177|180,182 Q:0,3|5,9|14,16|20,24|26,38|41,44|46,47|50,53|55,57|59,60|63,77|80,80|82,86|89,93|95,105|107,108|114,118|122,123|125,125|129,132|134,139|142,159|162,176|178,179|183,191 TTGG-GGGGT----TTS-??EEEES?HHHHHHHHHHHSS--EEEE?SS??TTTT?EEE?TT-?TTHHHHHHHHTTTTT--S?EEEEE??GGGGG?EEEEEEETTEE?SE-----EEEEE??-SS?S???GGGT?EEEEEE??HHHHHHHHHHHHHHHHTT??EEEEEEETTEEEEEE?SS???HHHHHHHSS 4IWX|A PF02958.15_EcKinase_seed 54 375 !Q:0,0|4,9|13,22|25,27|30,41|47,59|61,61|66,66|72,72|78,89|96,96|99,115|118,122|127,131|133,133|146,149|152,153|156,163|185,189|191,208|211,211|213,226|242,242|244,244|247,252|261,262|274,282|285,286|288,288|290,291|293,294|297,297|305,307|311,317|321,323|326,327|330,330|339,340|342,343|348,348|363,365|367,367 Q:1,3|10,12|23,24|28,29|42,46|60,60|62,65|67,71|73,77|90,95|97,98|116,117|123,126|132,132|134,145|150,151|154,155|164,184|190,190|209,210|212,212|227,241|243,243|245,246|253,260|263,273|283,284|287,287|289,289|292,292|295,296|298,304|308,310|318,320|324,325|328,329|331,338|341,341|344,347|349,362|366,366|368,374 ?SSS------EEE----------EE?-?TT--?-------??EEEEE-------------E?TTTS?HHHHH-HHHHH------------HHHHHH-TT?----------------SB?????BTTB-----S?EEETTEEEEEEE????EE??SS-------?HHHHHHHHHHHHHHHHHHTSS??---S------------------SS?B-------------?SHHHHTHHHHHHHHT?S-SS?-----TTTHHHHH--HHHHHHHHHHH---------HH??S?S??E??SS?SGGGEEE---SSS-------EEE???TT??EE?TTHHHHTT??S--SHHH-HHHHHHHHHHHHTS???G-GGGGGHH 3FEG|A PF02961.9_BAF_seed 9 90 !Q:0,4|14,15|18,18|26,27|39,40|55,56|69,71 Q:5,13|16,17|19,25|28,38|41,54|57,68|72,89 ?-???HHHHHHTTS??TT?BGGGSTT??HHHHHHHHHTT??BHHHHHHHHHHTTT?-HHHHHHHHHHHH???HHHHHHHHHHHHHHHHHH 2EZZ|A PF02962.10_CHMI_seed 3 126 !Q:0,0|31,31|35,35|39,39|55,55|57,58|69,69|72,73|110,111|125,125 Q:1,30|32,34|36,38|40,54|56,56|59,68|70,71|74,109|112,124 ?EEEEEEEGGGHHHHTHHHHHHHHHHHHHTT-SSS?GGG?EEEEEEESSEEETTS?S-?EEEEEEEEEE?TT??HHHHHHHHHHHHHHHHHHTHHHHTTSEEEEEEEEEE??SSSEEEEEGGGGG? 3E6Q|A PF02963.11_EcoRI_seed 3 257 !Q:0,1|16,17|33,33|43,43|57,57|62,64|69,69|72,73|76,76|82,82|86,86|98,100|109,110|116,116|120,123|143,143|146,147|158,158|161,161|166,166|170,170|175,175|178,178|182,183|194,195|199,201|203,203|207,207|211,212|216,218|223,223|227,230 Q:2,15|18,32|34,42|44,56|58,61|65,68|70,71|74,75|77,81|83,85|87,97|101,108|111,115|117,119|124,142|144,145|148,157|159,160|162,165|167,169|171,174|176,177|179,181|184,193|196,198|202,202|204,206|208,210|213,215|219,222|224,226|231,256 ??TTHHHHHHHHHHHT??HHHHHHHHHHHHHHH?TTSEEEEES?EEHHHHHHHHHTT?TTSS???SSTT?EE??TT?EEEEE?TTS?EEEEEEEEEEE???HHHHTTTT??BTTTT?BSS????SGGGGHHHHHHHHHHHTTT?SB??EEEEEESTTS?SS?EEEE?SSS?EEEE?TT?TTT??GGGTGGGGTT??SSS???B?EEE?SSS??EEE???EEEE?TTS????HHHHHHHHHHHHHHHHHHHGGGTHHH 1ERI|A PF02964.11_MeMO_Hyd_G_seed 3 161 !Q:16,17|38,38|40,41|67,67|75,75|79,79|95,96|118,118|145,145|155,155 Q:0,15|18,37|39,39|42,66|68,74|76,78|80,94|97,117|119,144|146,154|156,160 SSSBHHHHHHHHHHHT??SHHHHHHHHHHHHHHHSSTT?S??TTTTTHHHHHHHHHHHHHHHHHHHS?HHHHHHB?TTS?BHHHHHHHHHHHHHH??SHHHHHHHHHHHHHHHTTTTS?HHHHHHHHHHHHHHHHHHHTTTTTTS?HHHHHHHHT?EEEEE 1MTY|G PF02965.12_Met_synt_B12_seed 11 309 !Q:0,1|9,11|17,17|20,24|31,32|35,36|41,46|67,67|89,90|93,102|107,115|121,125|127,136|138,139|145,145|151,153|162,162|179,179|211,211|216,219|227,227|232,234|241,242|260,261|264,264|268,268|281,282|285,293|295,295|308,308 Q:2,8|12,16|18,19|25,30|33,34|37,40|47,66|68,88|91,92|103,106|116,120|126,126|137,137|140,144|146,150|154,161|163,178|180,210|212,215|220,226|228,231|235,240|243,259|262,263|265,267|269,280|283,284|294,294|296,307 ??HHHHHTT???HHHHH-HH-----HHHHHS??TT??GGGG??????HHHHHHHHHHHHHHHHHHTT?SEEEEEEEEEEEEEETTEEEE??TT??--------GGGS??-------SEEEE?????B?????????-B??GGGGS?BGGGS?-?EEEEEEEE-EEESHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS?TTTT????HHHHHTT?SSSB???TTSTTS??TTHHHHHHHHTTHHHHH??EE?TTS?EESSSEEEEEEB??TT-????????B?HHHHHHHHHHHT? 2O2K|A PF02966.11_DIM1_seed 20 139 !Q:2,2|4,5|17,17|28,28|61,62|64,65|72,72|74,78|81,81|96,105|107,108|110,110|129,129|134,138 Q:0,1|3,3|6,16|18,27|29,60|63,63|66,71|73,73|79,80|82,95|106,106|109,109|111,128|130,133 SS?B??SHHHHHHHHHT?SSSEEEEEEE?TTSHHHHHHHHHHHHHHHHHTTTEEEEEEETT--T??TTTTSS?S?----SS?EEEEEETTEEEEEE??????????S??S?HHHHHHHHHHHHHHHTTT?SEEE????? 1ERU|A PF02969.12_TAF_seed 10 68 !Q:1,4|17,19|21,21|52,52|56,56|64,65|67,67 Q:0,0|5,16|20,20|22,51|53,55|57,63|66,66 S????HHHHHHHHHHTT???B?HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?SSB?HHHHHHH--H? 1TAF|B PF02970.11_TBCA_seed 38 110 !Q:36,39|41,42|44,44|51,52|81,82|86,86|89,93|102,107 Q:0,35|40,40|43,43|45,50|53,80|83,85|87,88|94,101|108,109 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH----H?-S?THHHHH--HHHHHHHHTTHHHHHHHHHHHHHHHHHH--HHH?GG-----GTTSHHHH------HH 1QSD|A PF02971.9_FTCD_seed 4 147 !Q:0,1|11,11|13,14|28,36|61,61|66,66|83,84|93,93|95,95|112,116|135,137|147,147 Q:2,10|12,12|15,27|37,60|62,65|67,82|85,92|94,94|96,111|117,134|138,146 ??EEEEEEESS?H--HHHHHHHHHHSTT?????????STTEEEEEEEETTTTEEEEEEEES?TTTS?HHHHHHHHHHHHHHTT??EEEEEEES?B?HHHHHHHHHHHHHHHT?????HHHHHHHHHHHHTTTSSS???HHHHBHHHH- 2PFD|A PF02972.9_Phycoerythr_ab_seed 5 61 !Q:9,9|12,13|16,21|23,25|41,47 Q:0,8|10,11|14,15|22,22|26,40|48,60 EEEEEEEEE?TT?-SS??????S???SSGGGGEEEEEEEEE???---?HHHHHHHHHHHTT 1XG0|A PF02973.11_Sialidase_seed 6 203 !Q:0,1|8,9|16,16|20,20|23,23|35,35|47,51|61,62|66,66|80,80|88,88|92,92|100,101|103,105|113,114|142,142|145,149|156,157|169,169|174,176|188,190|201,202 Q:2,7|10,15|17,19|21,22|24,34|36,46|52,60|63,65|67,79|81,87|89,91|93,99|102,102|106,112|115,141|143,144|150,155|158,168|170,173|177,187|191,200 ??SSEEEE--EEEEEE?TTT?EE?TTSTTHHHHTT?SSEEEEEEEEE????-SEEEEEEEE??STT?TTEEEEEEEETTS?EEEEEEE?TTT?EEEEEES--S???SEETTEE??EEEEEEEETTTTEEEEEETTEEEEEEE?SS???--GGGSTT??EEEESSEEETT-EEES???EEEEEEEEESS???HHHHHHHHTT?? 2SLI|A PF02974.9_Inh_seed 27 119 !Q:0,1|3,7|12,12|19,34|37,37|49,49|59,59|67,67|71,73|78,78|86,86|90,90|101,101|107,107|110,112 Q:2,2|8,11|13,18|35,36|38,48|50,58|60,66|68,70|74,77|79,85|87,89|91,100|102,106|108,109|113,118 -?B?????HHHH?EEEEEE---------------?SS?EEEEEEEEEEE-ETTEEEEEE?HHHHHHH-SSS???EEEE?SSEEEEE?TTS?EEEEEEEETT-EEEEE?TT?-?EEEEEE 1SMP|I PF02975.9_Me-amine-dh_L_seed 2 123 !Q:0,0|4,7|11,11|23,23|33,34|38,39|42,42|45,45|47,48|67,67|73,76|82,83|86,88|95,95|99,101|104,104|108,109|115,117|122,122 Q:1,3|8,10|12,22|24,32|35,37|40,41|43,44|46,46|49,66|68,72|77,81|84,85|89,94|96,98|102,103|105,107|110,114|118,121 ?TTS????BSS?TTSTTBGGGGG?EEEBGGGGT??SSS??TT?EE?S??EEEEEEETTTTEEEEEEE?EEESS????SSEEE??TT???TTSGGG?SSS???TT?GGG??SEEEE???EEEE? 2J55|L PF02976.10_MutH_seed 50 127 !Q:1,1|4,16|21,21|29,29|33,46|48,48|50,50|57,57|61,61|64,66|70,71|87,88|92,92|94,99|102,102|105,107|111,113|115,115|117,118 Q:0,0|2,3|17,20|22,28|30,32|47,47|49,49|51,56|58,60|62,63|67,69|72,86|89,91|93,93|100,101|103,104|108,110|114,114|116,116|119,126 H-TS???????????--TTTT?EEEEEEE?TTS?-------------B?S?EEEEEE?SSS?TT?-?STT-?HHHHHHHSEEEEEEE??TTS?G------GG?BB???EEE???H-H--HHHHHHHH 2AOR|A PF02977.10_CarbpepA_inh_seed 7 58 !Q:0,7|9,9|11,11|23,33|35,37|39,39|44,44|47,48|56,57 Q:8,8|10,10|12,22|34,34|38,38|40,43|45,46|49,55 ------??S?B?SSSGGGSSSSS?---------?E---E-EEEE?SS??EEEEEES?? 1H20|A PF02978.14_SRP_SPB_seed 124 148 !Q:1,2|16,16|19,19|24,48|63,63|68,69|71,71|75,109|111,113|125,126|135,137 Q:0,0|3,15|17,18|20,23|49,62|64,67|70,70|72,74|110,110|114,124|127,134|138,147 S??HHHHHHHHHHHHS?SS?HHHH????-?????-----?????????-HHHHHHHHHHHHTS?HHHH--H?GGG?---------------------------------?H---HHHHHHHHHHT??HHHHHHHH---HHHHHHHHHH 1RY1|W PF02979.11_NHase_alpha_seed 37 205 !Q:0,2|22,23|53,53|63,63|72,75|77,79|82,93|101,102|111,111|115,118|123,123|125,126|141,141|148,148|152,155|165,166|169,169|175,178|181,181|184,185|193,194|203,204 Q:3,21|24,52|54,62|64,71|76,76|80,81|94,100|103,110|112,114|119,122|124,124|127,140|142,147|149,151|156,164|167,168|170,174|179,180|182,183|186,192|195,202 ???TTHHHHHHHHHHHHHHTTS??HHHHHHHHHHHHHTSSHHHHHHHHHHHHH?HHHHHHHHH?HHHHHHTT----T???TT--?---------SSEEEEE??SSEEEEEE?SSS????HHHH?S??GGGGSHHHHHHHTT?HHHHHH-HTT????TTSEEEEEE??SS?EEEEE????SS?TT??HHHHHTT??HHHHHTSS?? 3QXE|A PF02980.11_FokI_C_seed 4 146 !Q:13,13|26,30|43,43|49,52|64,65|70,72|79,81|103,104|109,117|123,123|128,128|141,146 Q:0,12|14,25|31,42|44,48|53,63|66,69|73,78|82,102|105,108|118,122|124,127|129,140 HHHHHHHHHHHTT?HHHHHHHHHTTT--???EEHHHHHHTSSS?SBTTB????HHHHHHHHHSS?-TTTT---THHHHS???HHHHHHHHHHHHHHHTTSEEE??EEEE?????????EEEES?EEEE?HHHHHHHHHTTT?????- 1FOK|A PF02981.10_FokI_N_seed 3 151 !Q:0,13|15,17|19,22|34,34|52,53|70,71|79,91|99,107|109,110|139,139|149,149 Q:14,14|18,18|23,33|35,51|54,69|72,78|92,98|108,108|111,138|140,148|150,150 ----??????--??S???S??-?HHHHHHHHTTS?TTSHHHHHHHHTHHHHH??SHHHHHHHHHHHHSSS??EEHHHHH?????????????SHHHHHS?????-???S??HHHHHHHHHHHHHTTSEEEETTTTEEEE?HHHHHHHHS?T 1FOK|A PF02982.9_Scytalone_dh_seed 3 160 !Q:0,2|24,24|68,68|74,75|108,110 Q:3,23|25,67|69,73|76,107|111,159 ???HHHHHHHHHHHHHHHHHHHHT?HHHHHTTEEEEEEEEEHHHHSEEEEEEEHHHHHHHHTSTTTTT?TTEEE??EEEEEEEEEEETTEEEEEEEEEEEEEEESSTT???EEEEEEEEEEEEEEEEEETTEEEEEEEEEEEEEEEESHHHHTHHHHHHH 5STD|A PF02983.9_Pro_Al_protease_seed 35 72 !Q:1,1|13,13|19,28|51,51|54,54|65,66 Q:0,0|2,12|14,18|29,50|52,53|55,64|67,71 S?HHHHHHHHHHH-HHHHH??????????TTEEEEEEEGGGTEEEEEEETT?HH-HHHHHHHHHT??TTTEE 3PRO|C PF02984.14_Cyclin_C_seed 240 236 !Q:0,1|9,12|14,14|17,27|29,31|33,55|57,57|59,66|77,82|87,87|90,101|106,106|115,116|124,129|132,152|160,166|179,182|187,189|193,195|198,199|201,205|219,227|230,230|234,235 Q:2,8|13,13|15,16|28,28|32,32|56,56|58,58|67,76|83,86|88,89|102,105|107,114|117,123|130,131|153,159|167,178|183,186|190,192|196,197|200,200|206,218|228,229|231,233 ??HHHHHHH----H-HH-----------S---S??------------------?--H-H--------HHHHHHHHHH------HHTT?GG------------GTTS?HHHHHHHH--HHHHHHH------SS-----?----------??-??HHHHHHS-??---?HHHHHHHHHHHH----HHHH---HHH---TT??S?-?--HHHHHTTSGGGTT---------GG-GSS?? 3EID|B PF02985.17_HEAT_seed 590 38 !Q:6,7|12,15|17,18|37,37 Q:0,5|8,11|16,16|19,36 THHHHH--HHTT---?S--SHHHHHHHHHHHHHHHHT? 1LRV|A PF02986.9_Fn_bind_seed 34 52 !Q:0,30|32,35|37,43|45,51 Q:31,31|36,36|44,44 -----??---?----?????--??????---B????S?---???B??????? 3ZRZ|C PF02991.11_Atg8_seed 9 106 !Q:12,12|23,23|26,28|30,32|34,35|58,59|63,63|71,75|88,89|93,93|101,103|105,105 Q:0,11|13,22|24,25|29,29|33,33|36,57|60,62|64,70|76,87|90,92|94,100|104,104 HHHHHHHHHHHH?TTEEEEEEEE?TT??-S???S??EEEEETTSBHHHHHHHHHHHTT??TTS?EEEESSS-????TTSBHHHHHHHH??TTS?EEEEEEE???B? 1KLV|A PF02994.9_Transposase_22_seed 3 395 !Q:0,167|220,223|226,227|243,243|246,253|260,269|271,273|296,296|309,311|333,335|367,367|380,395 Q:168,219|224,225|228,242|244,245|254,259|270,270|274,295|297,308|312,332|336,366|368,379 ------------------------------------------------------------------------------------------------------?----------------------------------????-------------------------??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTEEEEES????TT??HHHHHHHHHHHHHHH?TT????????EEEEEE??????????S???EEEEESSHHHHHHHHHHHHTTS?EEETTEEEEEEE???HHHHHHHHHTHHHHHHHHHTT???EEETTTEEEEESSSSEEEESSHHHHHHHHTT?HHHHHHHTTTTT?????????-?????- 2YKO|A PF02996.12_Prefoldin_seed 37 133 !Q:34,42|45,45|51,51|55,55|61,62|64,64|68,72 Q:0,33|43,44|46,50|52,54|56,60|63,63|65,67|73,132 HTTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHTT------???SS?EEEEE?SSS?EEEEE?-S?TTE-----EEEEEETTEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHT 1FXK|C PF03009.12_GDPD_seed 34 422 !Q:9,19|22,22|34,34|44,44|48,48|52,52|55,64|67,67|80,91|95,96|102,102|110,110|112,112|114,155|172,172|175,190|192,196|205,212|222,224|231,232|237,237|242,243|255,257|260,261|273,273|290,292|299,300|304,306|310,310|314,314|318,320|336,336|348,349|352,352|357,358|360,360|371,372|375,376|378,378|380,380|384,385|388,395|410,411|418,418 Q:0,8|20,21|23,33|35,43|45,47|49,51|53,54|65,66|68,79|92,94|97,101|103,109|111,111|113,113|156,171|173,174|191,191|197,204|213,221|225,230|233,236|238,241|244,254|258,259|262,272|274,289|293,298|301,303|307,309|311,313|315,317|321,335|337,347|350,351|353,356|359,359|361,370|373,374|377,377|379,379|381,383|386,387|396,409|412,417|419,421 TTTTTTTSS-----------TT?HHHHHHHHHTT?SEEEEEEEE?TTS?EEE?SS----------SB?TTTBSHHHHSTT??---------?TTS??BGGGS?HHHHHHS?B?S-----------------------------------------?EEEETTEEEESSTTSS?TT?---------------S?????BHHHHHHH--------HHHHHHHHS???EEEEEE??HHHH-HHTT??HHHHHHHHHHH---TT??STTSSBEEEES?HHHHHHHHHTHHHHHT???EEEEEE??GGG???EEE?TTS?EEE???GGGGSTTHHHHHTTT?SEEEEBGGGTB?-TT?BTTB??B?SHHHHHHHTT-?EE??B?B?TTS??TT-------?SSHHHHHHHHHTTS??SEEEES?HHH 3CH0|A PF03011.10_PFEMP_seed 41 191 !Q:17,17|20,39|50,50|59,59|72,76|78,99|105,105|124,125|141,148|163,163|166,166|186,190 Q:0,16|18,19|40,49|51,58|60,71|77,77|100,104|106,123|126,140|149,162|164,165|167,185 HHHHHHHHHHHHHHHHH-HH??????????-??-????--TTHHHHHHHH-HHHHHHHH-HHHHHHHHHHTT?????S----------------------HHHHH-HHHHHHHHHHHHHHHHHS??HHHHHHHHHHHHHTT?????---SGGGHHHHHHHGGG?SS?HHHHHHHHHHHHHHHHHHH????? 2C6J|A PF03012.9_PP_M1_seed 11 300 !Q:0,198|213,214|228,228|233,235|257,260|273,273|281,281 Q:199,212|215,227|229,232|236,256|261,272|274,280|282,299 ?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????-????????????????????????????????????????????????????????-????????HHHHHHHHHHHTTT??EEEEBSSSSEEEE?GGGG???HHHHHHHHTTSTTHHHHHHTT????HHHHHHHHHHHH?HHHHHHB?HHHHHHHHHHHHHHHHHH 3OA1|A PF03013.9_Pyr_excise_seed 26 154 !Q:0,5|7,7|12,12|27,27|39,40|45,47|50,51|53,60|91,96|98,99|101,104|108,114|119,124|142,142|146,147|152,153 Q:6,6|8,11|13,26|28,38|41,44|48,49|52,52|61,90|97,97|100,100|105,107|115,118|125,141|143,145|148,151 ??????S?GGGS?HHHHHHHHHHTTHH-HHHHHHHHHTT??GGGS???SS??S--------STTTTGGGTTBHHHHHHHHHHHHHHHHHTT---???S??S????TTS?------GGGB??????HHHHHHHHHHHHHHHHH?GGG??BTTB?? 2FCC|A PF03014.9_SP2_seed 2 639 !Q:0,82|85,86|89,89|103,106|109,109|119,120|123,125|131,132|156,156|158,158|164,165|173,173|177,178|180,181|196,196|199,200|206,206|221,222|226,226|231,231|233,233|242,243|252,253|255,256|268,268|271,271|276,276|278,278|293,293|302,302|315,316|318,320|323,323|325,325|327,328|336,336|344,344|362,363|368,368|383,385|387,387|390,390|405,406|412,414|418,421|424,424|426,426|429,429|435,439|441,441|443,452|455,455|460,462|478,479|485,485|489,490|495,496|501,501|506,507|512,512|514,514|516,521|525,534|536,540|542,542|550,551|555,556|558,559|562,563|566,567|575,638 Q:83,84|87,88|90,102|107,108|110,118|121,122|126,130|133,155|157,157|159,163|166,172|174,176|179,179|182,195|197,198|201,205|207,220|223,225|227,230|232,232|234,241|244,251|254,254|257,267|269,270|272,275|277,277|279,292|294,301|303,314|317,317|321,322|324,324|326,326|329,335|337,343|345,361|364,367|369,382|386,386|388,389|391,404|407,411|415,417|422,423|425,425|427,428|430,434|440,440|442,442|453,454|456,459|463,477|480,484|486,488|491,494|497,500|502,505|508,511|513,513|515,515|522,524|535,535|541,541|543,549|552,554|557,557|560,561|564,565|568,574 --------????????????????????----------????????????--???????????????????????????????SS??SS?SEEEEEEEEEEEE????TT?SEEEEEEEE??TT???SSSEE??HHHHHHTTBSEEEEEEEEEEEEE?S?TTEES??EEEEEES?TTS??S??SHHHHHTSSSEEEE?SS??EEEEE?HHHHHTTGGGEEES??TTS?HHHH?S?EEEEEEES??EETTTTEE??S??EEEEEEEEEEE?SB?TTSS?S?EEEEEEEEEEEEEE?SSSBEEEE?TTHHHHHSBGGG-?S???TT?B?S??EEEEEEE?HHHHTTS?HHHHHTTTTTEEEEEEE??SSSS?EEEEESSHHHHHTT???B?SS?EEEEEEEEEEEESS??BSSSS???SSS????SS?B?TT?EEEEE-----E?S??-----???TT?SSSS???EEESSEEEEETTTTB??BTTTS?GGG??BTTB??EEEE?SSSE--EEEE?B?S??????SSS??????????S?????E-EEESSSS??EEE??S??TT??SS??EEEEEEB?????------------------------------------??--------------------- 2ZTN|A PF03020.10_LEM_seed 8 43 !Q:0,2|6,6|19,25 Q:3,5|7,18|26,42 ???EEE?HHHHHHEEEBTT???????SSEHHHHHHHEHHHHHH 1GJJ|A PF03022.11_MRJP_seed 20 335 !Q:1,1|8,8|18,18|21,21|24,24|32,36|48,49|56,57|61,67|80,80|84,85|88,88|101,103|120,120|122,123|127,129|131,131|144,152|159,162|166,167|176,176|192,205|211,212|215,216|223,223|227,227|246,246|249,249|258,259|261,261|264,266|274,274|276,288|290,291|297,297|299,300|306,308|311,311|320,324 Q:0,0|2,7|9,17|19,20|22,23|25,31|37,47|50,55|58,60|68,79|81,83|86,87|89,100|104,119|121,121|124,126|130,130|132,143|153,158|163,165|168,175|177,191|206,210|213,214|217,222|224,226|228,245|247,248|250,257|260,260|262,263|267,273|275,275|289,289|292,296|298,298|301,305|309,310|312,319|325,334 S?EEEEEE?TTSEEEEEE?SS?SS?STTGGGS?????EEEEEESSSTT??EEEEEE??GGG??----?GGGEEEEEEEES?TTT--TS?SEEEEEEETTTT---EEEEEETTTTEEEEEE?G--GGS??-S?EEEEETTEEEEE???------EEEEEE????TTS??EEEEEETT?SEEEEEEHHHHSSTT?????---------EEEEE??TT??EEEEEE?TTT?EEEEEESSSSEEEEEETS?SB?GGGEEEEE--E?TT-??SEEEEEE?T-------------T??EEEEE?S??STGGG???SS?SEEEEEES?----HHHHHTTSTT 3Q6T|A PF03024.9_Folate_rec_seed 34 298 !Q:0,0|3,14|18,18|21,22|26,26|32,42|49,76|81,93|99,99|105,110|127,127|129,130|135,145|147,162|168,169|171,172|174,175|177,177|191,191|193,195|198,198|200,200|204,207|209,209|214,215|217,218|221,225|232,234|241,259|268,270|273,273|276,291|297,297 Q:1,2|15,17|19,20|23,25|27,31|43,48|77,80|94,98|100,104|111,126|128,128|131,134|146,146|163,167|170,170|173,173|176,176|178,190|192,192|196,197|199,199|201,203|208,208|210,213|216,216|219,220|226,231|235,240|260,267|271,272|274,275|292,296 ?EE-----------?TTS?EE??BSB?GGGTT----------?GGGTTS----------------------------BSSB????????????-TTTSS?TTTTS?---??HHHHHHHHHHHHHHHH?S??GGGB---------?-S?--------------?TTSSS??B??B?-B?HHHHHHHHHHTTT?E---ES?S?TTS--??B?TTSS-?B??TT??--?EEHHHH?-?SHHHHH-------------------HHTTTTSB???SS?TT----------------SSSSB? 4KN2|A PF03028.10_Dynein_heavy_seed 18 882 !Q:0,4|11,12|26,26|29,39|52,55|63,63|66,66|68,68|70,74|85,90|93,95|111,111|128,130|135,141|148,151|155,155|159,159|162,162|165,165|168,170|183,194|217,217|221,221|223,231|235,235|241,241|250,258|261,261|265,266|270,270|273,277|279,279|289,290|292,294|308,312|314,314|323,323|349,357|360,360|363,367|389,389|391,393|398,401|418,419|443,444|446,446|451,456|462,466|479,479|481,481|483,485|492,492|520,559|569,604|630,661|663,665|668,669|690,705|711,711|728,739|741,776|780,780|782,782|787,787|790,790|792,793|798,799|806,808|812,822|834,834|841,853|863,863|867,867|876,876|881,881 Q:5,10|13,25|27,28|40,51|56,62|64,65|67,67|69,69|75,84|91,92|96,110|112,127|131,134|142,147|152,154|156,158|160,161|163,164|166,167|171,182|195,216|218,220|222,222|232,234|236,240|242,249|259,260|262,264|267,269|271,272|278,278|280,288|291,291|295,307|313,313|315,322|324,348|358,359|361,362|368,388|390,390|394,397|402,417|420,442|445,445|447,450|457,461|467,478|480,480|482,482|486,491|493,519|560,568|605,629|662,662|666,667|670,689|706,710|712,727|740,740|777,779|781,781|783,786|788,789|791,791|794,797|800,805|809,811|823,833|835,840|854,862|864,866|868,875|877,880 ?????GGGTTT??HHHHHHHHHHHHH?GG-----------GTTHHHHHHHTH----HHHHHHT?SS?S-S?????TTHHHHHHHH------SS???HHHHHHHHHHHHHHH?GGGHHHHHHHHHHHHS--?TTTT??-????HHHHHH----HSS?TTS?EE?EE?TT???HHHHHHHHHHHT------??????BTTSHHHHHHHHHHHHHHHHHT?EEE?B--------?GGG?TTTHH-HHHHHHHT???-----?TT?EEE??EES?TT-----S?HHHHHTSEE??B???SSHHHHHHHHHTT-----S?HHHHTSSS-THHHHHHHHHHHHHHHHHHGGGGTT---------TS?SS?????HHHHHHHHHHHHHHHHHHSTT?S???TTTS?---HHHHHHHHHHTTTSTT??SSSHHHHHHHHHHHHSSGGGGSS--S?EEEG------GGTEE????-SSHHHHHHHHTT-S?S???GGGGTS?TTHHHHHHHHHHHHHHHHHHHHHHTTT?????????--???????---------------------?HHHHHHHHH??????????---???????????????--??????HHHHHHHHHHHHHHHHHHHHHHHHH????????????????????????????????S???SS??HHHHHHHHHHHHHHHHHHHH?------?????????GGGSS?HHHHHHHHHHHHHHHT--??????????B????????????--------------------?---EEE?S?EEES?EE?S--SSEE??SSSEEE???EEE????????--?TTSGGGEEEEE-EESSTT???----------EEEEEEEEB?TTS?HHHHHTTT?EEES? 4AKH|A PF03029.12_ATP_bind_1_seed 30 321 !Q:3,3|7,7|23,23|25,25|31,32|35,38|41,42|50,51|59,61|63,64|75,105|119,142|149,149|151,153|159,160|182,187|194,194|198,198|201,203|224,224|230,231|236,236|240,241|251,251|262,263|269,278|292,296|299,300|304,304|320,320 Q:0,2|4,6|8,22|24,24|26,30|33,34|39,40|43,49|52,58|62,62|65,74|106,118|143,148|150,150|154,158|161,181|188,193|195,197|199,200|204,223|225,229|232,235|237,239|242,250|252,261|264,268|279,291|297,298|301,303|305,319 EEE?TTS?HHHHHHHHHHHHTTT-S?EEEEE??SS????SS??SEETTTT??HHHHHTT---T??HHHHHHHHHH-------------------------------HHGGGHHHHHHHH------------------------HHHHTT?S---EEEEE??SSTHHHHTSHHHHHHHTTSSS-----?EEEEEE?GGG?SS---HHHHHHHHHHHHHHHHHHTS?EEEEE??GGGS?HHH--HHHHHHHHH?HHHHTTTSSS??SHHHH----------HHHHHHHHTTTTS?????EE??TTT?TTHHHHHHHHHHHHH? 1YR8|A PF03030.11_H_PPase_seed 139 1310 !Q:18,152|188,189|194,197|201,201|203,209|216,219|221,241|252,255|260,260|298,313|315,315|317,330|365,366|372,387|389,389|435,437|440,440|443,443|467,467|481,483|494,494|497,510|518,518|538,637|670,687|693,702|714,724|726,730|755,755|768,768|772,772|807,830|870,870|872,873|884,903|938,1045|1047,1049|1051,1054|1106,1131|1135,1136|1138,1140|1174,1175|1177,1189|1191,1203|1240,1248|1250,1251|1255,1255|1257,1257|1261,1261|1268,1272 Q:0,17|153,187|190,193|198,200|202,202|210,215|220,220|242,251|256,259|261,297|314,314|316,316|331,364|367,371|388,388|390,434|438,439|441,442|444,466|468,480|484,493|495,496|511,517|519,537|638,669|688,692|703,713|725,725|731,754|756,767|769,771|773,806|831,869|871,871|874,883|904,937|1046,1046|1050,1050|1055,1105|1132,1134|1137,1137|1141,1173|1176,1176|1190,1190|1204,1239|1249,1249|1252,1254|1256,1256|1258,1260|1262,1267|1273,1309 HHHHHHHHHHHHHHHHTS????---????????????????????----------------------------------------------------------------------------------------------------????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--HHHH----HHH-H-------HGGGTT????E---------------------EETTEEEEEE?--?HHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT----------------T-T?-------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--HHHHT----------------T?HHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS???TT?TT?TTHHHHHHHHHHTTTHHHHHHHH-HHHHHHHHHHHHH---HHTSHHHHTT?HH--------------HHTHHHH-HHHHHHHHHHHHHHHHHTT???------------------------------------------------------------------------------------------------?SGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHS-----------------?SEEEE----------EETTEEEEEEH-----------H-----HHHHHHHHHHHHHHHHHHHHHHHH?TTSHHHHHHHHH-GGG?HHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHH------------------------HHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHT-T??HHHHHHHHHH--------------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT------------------------------------------------------------------------------------------------------------T?--S??--BSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTTT--------------------------TTS--S???HHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHH--T?------------H-------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---------H??SHH-H-HTT?STTSHH-----HHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHH 4AV3|A PF03031.13_NIF_seed 120 319 !Q:0,0|5,6|10,12|20,21|23,34|36,36|41,48|51,61|65,67|78,84|91,93|96,96|99,99|103,104|111,111|114,116|128,135|137,141|143,144|146,148|153,157|159,166|168,170|174,179|184,184|187,187|189,195|200,220|223,234|244,244|251,252|259,268|271,278|281,292|297,299|305,305|310,311|313,314|316,316 Q:1,4|7,9|13,19|22,22|35,35|37,40|49,50|62,64|68,77|85,90|94,95|97,98|100,102|105,110|112,113|117,127|136,136|142,142|145,145|149,152|158,158|167,167|171,173|180,183|185,186|188,188|196,199|221,222|235,243|245,250|253,258|269,270|279,280|293,296|300,304|306,309|312,312|315,315|317,318 ?EEEE??BTT---TEEEESS??S------------S?SEEE--------EE-----------EET---TEEEEEEEEE------?TTHHHH---HH-HH-HHH--SEEEEE?SS?--HHHHHHHHHHH?-------T-----T??E---EEEE----?G--------G---GSE------EETT-EE-E--?---?GGGS---------------------SS-?----------GGGEEEEES?GGGGTT?-GGGEEE???------?SS?-------TT-??---------HHHH---HHHHH-HHHT--T?-S?HH 3L0C|A PF03033.15_Glyco_transf_28_seed 43 187 !Q:5,5|26,26|30,31|35,35|44,44|50,50|55,59|61,97|102,104|111,111|130,131|151,155|159,160|166,166|170,171|181,181 Q:0,4|6,25|27,29|32,34|36,43|45,49|51,54|60,60|98,101|105,110|112,129|132,150|156,158|161,165|167,169|172,180|182,186 EEEEE?SSHHHHHHHHHHHHHHHTTT?EEE--EEE?TTSTHHHH-TGGGT?EEEE--???G-------------------------------------GGSS??-SHHHHH?THHHHHHHHHHHHHHHHH??SEEEEEESTTHHHHHHHHH-----HTT??EEEEE?SSS??HHHHHHGGG?SEEEE 4AMG|A PF03036.11_Perilipin_seed 17 460 !Q:0,194|199,200|208,235|238,239|249,249|252,252|261,261|302,349|366,378|396,396|420,421|426,430|458,459 Q:195,198|201,207|236,237|240,248|250,251|253,260|262,301|350,365|379,395|397,419|422,425|431,457 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------????????????????EESS?-HHHHHTT???------------------------?TT??HHHHHHHHH-TT?EEEEGGGS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH????---?????????????????????????----------??????SHHHHHHHHHHHHHHH-------------HHHHHHHHHHHHTTTTS?HHHHHHHHHHHHHHHHHHHHGGG??SGGG---??HHHHHHHHHHHHHHHHHHHHHHHHHHT?? 1SZI|A PF03039.9_IL12_seed 3 226 !Q:0,46|67,84|90,90|100,108|110,110|112,121|155,157|174,195|224,225 Q:47,66|85,89|91,99|109,109|111,111|122,154|158,173|196,223 --------------------------????????????-????????HHHHHHHHHHHHHHHHGGGS??????????????????HHHHT?BGGGGGSTT?????????B?S??????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSTT???SHHHHHHHHHHHHHHH?????????????--???????HHHHHHHHHHHHHHHHHHHHHHHHHHHH?? 1F45|B PF03045.10_DAN_seed 20 135 !Q:0,1|10,10|15,18|29,29|41,43|47,48|67,68|73,74|76,83|88,88|104,104|113,116|130,134 Q:2,9|11,14|19,28|30,40|44,46|49,66|69,72|75,75|84,87|89,103|105,112|117,129 ??THHHHHTT?GGGG----GGTSHHHHTS?EEEEEEEEEEE-??TTS??EEEEEEEEEEEEEEEEEE??BSSS??E--------EEEE?EEEEEEEEEEEEEEE?TTSSSSEE----EEEEEEEEEEEEE????? 2K8P|A PF03051.10_Peptidase_C1_2_seed 13 458 !Q:2,2|16,16|30,30|37,37|39,39|45,49|53,53|56,57|60,61|63,64|88,88|91,92|94,94|122,123|135,135|138,142|154,156|162,165|171,171|191,191|198,199|223,230|239,239|242,243|251,251|265,265|274,277|281,281|291,292|297,300|305,306|322,323|329,329|342,342|347,347|354,355|357,357|359,359|361,361|371,374|385,385|388,388|391,391|399,399|402,402|433,433|443,447|451,451|454,454 Q:0,1|3,15|17,29|31,36|38,38|40,44|50,52|54,55|58,59|62,62|65,87|89,90|93,93|95,121|124,134|136,137|143,153|157,161|166,170|172,190|192,197|200,222|231,238|240,241|244,250|252,264|266,273|278,280|282,290|293,296|301,304|307,321|324,328|330,341|343,346|348,353|356,356|358,358|360,360|362,370|375,384|386,387|389,390|392,398|400,401|403,432|434,442|448,450|452,453|455,457 SS?HHHHHHHHHHHTT?HHHHHHHHHHTTS?HHHHHB?H-HHHHH?????SEE?SS??SS??B??BSSTHHHHHHHHHHHHHHHHHHT?SS??B?HHHHHHHHHHHHHHHHHHHHHHHHHTT??TTSHHHHHHHH?TT?????HHHHHHHHHHH???BGGGS???-TGGGB?HHHHHHHHHHHHHHHHHHH-HHHHTT??HHHHHHHHHHHHHHHHHHHHHHH????----SSEEEEEE?TT??EEEEEEE?HHHHHHHHTTTTS?GGGEEEEE????TTS?SSEEEEETT??SSTT????EEEE??HHHHHHHHHHHHHTT??EEEEE?TTTTEETTTTEE?TTSB?HHHHHS??S?S-S?HHHHHHTTS????EEEEEEEEEE?TT?SS?EEEEEEE?SB?TTSTBTTEEEEEHHHHHHHEEEEEEEGGGS?HHHHGGGGS---??EEE?TT?GGG 1AU2|A PF03054.11_tRNA_Me_trans_seed 21 427 !Q:0,0|6,7|9,9|23,25|34,41|46,54|74,75|81,81|101,104|125,129|132,133|138,140|142,142|148,170|178,179|185,186|193,194|203,204|209,211|224,248|258,264|271,277|282,282|284,287|291,292|295,296|300,304|310,311|332,332|336,336|350,359|372,377|384,385|388,388|390,390|401,403|415,418 Q:1,5|8,8|10,22|26,33|42,45|55,73|76,80|82,100|105,124|130,131|134,137|141,141|143,147|171,177|180,184|187,192|195,202|205,208|212,223|249,257|265,270|278,281|283,283|288,290|293,294|297,299|305,309|312,331|333,335|337,349|360,371|378,383|386,387|389,389|391,400|404,414|419,426 ?EEEEE??S?STTHHHHHHHHTT?-?EEEEEEEE????---?SHHH---------HHHHHHHHHHHHHHHHHHT??EEEEE?HHHHHHHTHHHHHHHHHTT????HHHHHHHHTTTTHHHHHHHH-----TT??SEEE???S?EEEEE-----------------------TTEEEEE??SSTTT??GGGGSS??HHHHHHEE??GGGS?--HHHHHHHHHHTT??---?????????????????---HHHHHHTTS???--??EEEETT-----??EEEE?S?---STT??TT??TTS?????SSSTT??EEEEEEETTTTEEEEEESTT?TTT?EEEEEEEEEEETT-----?????SEEEEEEESSTT?---??EEEEEE??SS-S?EEEEEEEEES???TTSEEEEEETT----EEEEEEEE 2DER|A PF03055.10_RPE65_seed 151 1158 !Q:5,7|9,9|11,11|15,21|24,24|26,28|31,33|39,42|44,45|47,47|49,60|64,67|70,70|77,77|86,92|96,104|106,106|112,114|122,123|127,129|131,133|136,136|140,142|145,165|173,203|205,209|216,218|221,250|256,257|261,263|267,267|269,272|275,276|281,286|289,312|316,327|330,333|335,336|340,340|343,343|349,350|358,363|370,374|376,377|384,392|396,410|415,415|419,419|423,424|426,434|437,437|446,448|451,453|455,456|461,463|468,468|471,505|511,511|515,515|518,518|525,527|529,532|534,562|568,572|582,585|587,588|592,606|616,618|620,667|670,676|680,695|700,703|714,716|718,796|798,804|807,807|810,813|818,823|825,827|833,846|853,855|860,881|884,896|898,898|904,926|932,943|946,949|952,974|977,980|983,1014|1018,1018|1020,1022|1024,1024|1028,1031|1036,1040|1042,1055|1057,1074|1078,1078|1089,1091|1094,1105|1107,1109|1113,1114|1122,1124|1128,1130|1132,1133|1137,1137|1139,1139|1142,1151|1157,1157 Q:0,4|8,8|10,10|12,14|22,23|25,25|29,30|34,38|43,43|46,46|48,48|61,63|68,69|71,76|78,85|93,95|105,105|107,111|115,121|124,126|130,130|134,135|137,139|143,144|166,172|204,204|210,215|219,220|251,255|258,260|264,266|268,268|273,274|277,280|287,288|313,315|328,329|334,334|337,339|341,342|344,348|351,357|364,369|375,375|378,383|393,395|411,414|416,418|420,422|425,425|435,436|438,445|449,450|454,454|457,460|464,467|469,470|506,510|512,514|516,517|519,524|528,528|533,533|563,567|573,581|586,586|589,591|607,615|619,619|668,669|677,679|696,699|704,713|717,717|797,797|805,806|808,809|814,817|824,824|828,832|847,852|856,859|882,883|897,897|899,903|927,931|944,945|950,951|975,976|981,982|1015,1017|1019,1019|1023,1023|1025,1027|1032,1035|1041,1041|1056,1056|1075,1077|1079,1088|1092,1093|1106,1106|1110,1112|1115,1121|1125,1127|1131,1131|1134,1136|1138,1138|1140,1141|1152,1156 HHTTS???S?E-EEE----???EE-E???TT?-?EEEEE??--B??S-E------------ETT----EE?SSGGGS?BEEEEEEE?------SSS---?----?E-EEEEE???HHHHHHH--HHT---S-??SB?TTS???SS---------------------THHHHTT??----------------------------?B?????SEEEEE---TT------------------------------EEEEE-?TTS-??EEE?T----TT??EEEE---??-TT------------------------TTS?-----------TT????S??EEE-SS?TTTTT??EEEEEEE------EESSEE-----E--EEEEEE--------?TTS-------------?-EEEE-EEE-EEE--S--???????EE?SSEEEEEE?-?EE---E??HHHH---TTSS?GG-----------------------------------GGEEE?TTS?EE-EEEEET---T----S-----------???---------------EEEEE-???-EEEEEEEEE----E--ETT---------------EEEEEEEEE---S???-??-----------------------------------------?TT?-----?GGG--?------------?GGGS?-??EEEEEEEETT---T-------------------------------------------------------------------------------T-------EE-EE----EEEE-----?S--?EEEEE?-----------?-GGGTTS?-?SEEE----------------------EE-------------E?SSSSS-----------------???-??EEEEE------------ET----TT-----------------------TE----EE--------------------------------EEE?T---T-TEE????EEEE----?T--------------T?----------?------STT?EEEEEEEEET---TT------------T---EEE--EEEEETT--?TTS-??S--EEE-E?SS-??--?????EEEEE? 3FSN|A PF03059.11_NAS_seed 13 327 !Q:4,4|8,9|26,26|28,48|51,51|53,54|63,63|95,95|97,97|120,120|126,127|130,134|140,142|145,145|153,159|163,185|206,209|213,214|222,223|230,233|239,239|242,242|244,248|260,261|264,264|270,270|272,273|276,280|286,288|290,291|296,297|306,309|312,314|321,326 Q:0,3|5,7|10,25|27,27|49,50|52,52|55,62|64,94|96,96|98,119|121,125|128,129|135,139|143,144|146,152|160,162|186,205|210,212|215,221|224,229|234,238|240,241|243,243|249,259|262,263|265,269|271,271|274,275|281,285|289,289|292,295|298,305|310,311|315,320 GGTT?GGG??TTTTHHHHHHHHHHHT?T---------------------TS?H--HHHHHHHH?GGGHHHHHHHHHHHHHHHHHHHHHHHHHHHH?S-SHHHHHHTSTTHHHHHHHHHHH-HHHTT??TT---?-EEEEE???SS?HHHHHHH-------HTT---------------------??EEEEEESSHHHHHHHHHHHH----HHT??SEEEEES?-GGGGGG?-??SEEEE?TT?S----?HHHHHHHHHHH??TT?EEEEE-E??GG-----GGGSS???T--GGGT--TEEEEEEE???-TT???EEEEEE?????? 3FPH|A PF03060.10_NMO_seed 12 445 !Q:0,1|9,9|16,18|21,21|24,24|42,44|47,48|50,57|71,71|74,75|91,114|123,123|125,159|167,169|181,181|201,208|210,210|215,215|222,229|232,237|249,249|251,257|259,259|266,267|280,280|295,296|298,298|308,309|312,312|317,317|321,329|331,332|337,338|347,350|355,355|362,392|398,401|409,413|417,419|421,422|428,429|431,431|433,433|445,445 Q:2,8|10,15|19,20|22,23|25,41|45,46|49,49|58,70|72,73|76,90|115,122|124,124|160,166|170,180|182,200|209,209|211,214|216,221|230,231|238,248|250,250|258,258|260,265|268,279|281,294|297,297|299,307|310,311|313,316|318,320|330,330|333,336|339,346|351,354|356,361|393,397|402,408|414,416|420,420|423,427|430,430|432,432|434,444 ??HHHHHHT?SSSEEE???TT-TS?HHHHHHHHHTTSBEEEE--?TT??H--------HHHHHHHHHHHTT?SS-?EEEEEETTSTTHHHH------------------------HHHHHHTT?S-----------------------------------EEEEESS??-HHHHHHHHHTT?EEEEEESSHHHHHHHHHTT-------?S?EEEE?TTSSEE??------SS?-----HHHHHHHHHHH?S-------S?EEEESS??SHHHHHHHHHHT?SEEEESHHHHTBSS??S?HHHHHHHHH??TT?EEEE?TTT---------T??EEEE??HHHHHHHH----HHHH?HHHHHH-------------------------------HHTTH----HHHHHTT?---?TTT???B??GGGGG??S?B?HHHHHHHHHHH- 1VZW|A PF03061.17_4HBT_seed 140 98 !Q:4,4|9,12|29,29|31,43|46,46|57,57|59,62|65,66|78,78 Q:0,3|5,8|13,28|30,30|44,45|47,56|58,58|63,64|67,77|79,97 TSSB?HHHH----HHHHHHHHHHHHHHHH?T-------------TS?EEEEEEEEEE?S?-??SS--EEEEEEEEEEE?SSEEEEEEEEEETTEEEEE 1VH5|A PF03063.15_Prismane_seed 251 930 !Q:0,1|3,4|8,11|15,15|17,17|19,19|23,40|44,45|56,56|70,70|76,83|98,118|124,125|141,143|150,150|152,154|156,186|191,194|205,213|215,216|222,225|228,229|247,255|261,272|277,277|279,281|284,284|297,298|300,301|304,305|307,310|325,325|341,351|356,356|358,360|363,365|373,373|389,389|395,399|413,414|416,416|419,425|430,430|445,445|447,447|454,464|467,469|480,480|482,485|488,488|490,490|493,510|513,517|519,543|554,586|589,594|598,606|615,628|630,652|658,710|717,717|722,723|725,727|729,729|734,735|745,746|754,754|762,764|768,770|773,781|783,783|785,803|810,811|827,828|833,838|840,841|843,843|850,854|860,863|879,882|888,889|892,893|904,907|909,912|914,920|928,929 Q:2,2|5,7|12,14|16,16|18,18|20,22|41,43|46,55|57,69|71,75|84,97|119,123|126,140|144,149|151,151|155,155|187,190|195,204|214,214|217,221|226,227|230,246|256,260|273,276|278,278|282,283|285,296|299,299|302,303|306,306|311,324|326,340|352,355|357,357|361,362|366,372|374,388|390,394|400,412|415,415|417,418|426,429|431,444|446,446|448,453|465,466|470,479|481,481|486,487|489,489|491,492|511,512|518,518|544,553|587,588|595,597|607,614|629,629|653,657|711,716|718,721|724,724|728,728|730,733|736,744|747,753|755,761|765,767|771,772|782,782|784,784|804,809|812,826|829,832|839,839|842,842|844,849|855,859|864,878|883,887|890,891|894,903|908,908|913,913|921,927 ??B??STT?---GGG-T?B-SSS-----------------?TTS??HHHHHHHHHH-HHHHHHHHHHHHH-HHHTT??----??HHHHHHHHHHHHHT---------------------STTTB??HHHHHHHHHHHHHHH---HHHHHH?S???S-----------------------------??HHHH????SHHHHHHHHT---------T--TSGGG??--SH--HHHHHHHHHHHHHHHHH---------HHHHH------------HHHT-T???HH-HHHHHHHHHHHT--T?-TT??H----HHHHHHHHHHHHHH-HHHHHHHHHHHHHHH???----??--EEEE?S??-SS--?EEEEESS?HHHHHHHHHHTTTSS?EEEEE-----GGGGGGGGSTGGG--G?TT-------EEEE?SSSGGGHHHHHHHT?S?EEESSS?????----?-HH---HHTTEEEETT?B?---TT-S?EE---?-------------?SS-----S--------------------?????HHHHHHHHTS????-------------??------------??SE------EEE------???HHHHHTTH--------------H-----------------------HHHHH-----------------------------------------------------HHHTSS?EEEE??B???S?GGGH--HHHHHHHHS-?TTEEEEE?SGGGGGT---TTS???EE---------T-T-------------------EESEEE??SGGGHHHHHHHHHHH--HHHT------T-?S?GGGSSE-----EEEEE?--?SHHHHHHHHHHHHTT????EEESS??TT??HHHHHHHHHH----H--??B?--??-?HHHHHHH?? 1GNT|A PF03065.10_Glyco_hydro_57_seed 22 656 !Q:6,10|14,16|28,44|51,60|74,81|87,87|96,96|121,174|176,176|180,238|259,259|267,269|276,277|284,284|287,287|289,289|293,293|295,315|336,338|340,341|346,346|350,350|352,353|359,359|363,363|367,367|369,370|380,381|386,386|392,396|401,407|410,410|414,414|417,422|428,431|436,437|446,446|454,454|459,459|462,481|483,501|504,507|510,511|516,516|520,521|523,524|538,554|574,575|587,620|645,647|655,655 Q:0,5|11,13|17,27|45,50|61,73|82,86|88,95|97,120|175,175|177,179|239,258|260,266|270,275|278,283|285,286|288,288|290,292|294,294|316,335|339,339|342,345|347,349|351,351|354,358|360,362|364,366|368,368|371,379|382,385|387,391|397,400|408,409|411,413|415,416|423,427|432,435|438,445|447,453|455,458|460,461|482,482|502,503|508,509|512,515|517,519|522,522|525,537|555,573|576,586|621,644|648,654 EEEEEE?????TTS?-?SSSSHHHHHHH-----------------HHHTHH----------HHHHHHHHHHHTT??----??EEEEE?HHHHHHHT?HHHHHHHHHHHHHHHHHHHHHHHH?----------------------------------------------------?S?HHH-----------------------------------------------------------HHHHHHHHHHHHHHHHHTTT?HHHHHHH---HHHTTS--EEEEEE?TT?B?GGG?S?--------------------HHHHHHHHHHHHHHHHHHHS---S??SBEE?GGG?B??SEEEE?GGG?EEE-E??HHHHHHTTT??EEEE?HHHHH?????SSTT???????SS?SSS?EE------ETTSS---?EEEE??HHHHHHHH?TTTSGGG?TTSB?SS-----------------???T-------------------TT????BB??SSSS?GGG??B??HHHHHHHHHHHHH-----------------HHHHHHHHHHHHHHHHHSS??EEEEEEEGGGB----------------------------------TTTBTTHHHHHHHHHHHHHHTTEE???HHHHHHT? 1K1W|A PF03066.10_Nucleoplasmin_seed 23 210 !Q:0,2|7,8|11,11|14,16|20,38|48,48|51,52|54,54|56,56|64,66|68,68|74,74|98,98|109,111|120,209 Q:3,6|9,10|12,13|17,19|39,47|49,50|53,53|55,55|57,63|67,67|69,73|75,97|99,108|112,119 ???EEEE??EE?SS?-?EEE??------???----????EEEEEEEEE?SS??S-S?EEEEEEE---E?TTSSE-EEEEEEEEBTTTBSEEEEEEEEE?SSEEEEEEES???EEEEEEEE???----------------------------------------------------------???????-------------------??? 1XB9|A PF03067.10_Chitin_bind_3_seed 128 351 !Q:0,0|6,10|13,13|21,21|25,82|84,84|89,89|93,97|99,113|119,130|133,133|138,138|140,149|151,153|158,161|164,169|172,172|175,176|178,180|183,192|196,196|198,199|208,210|212,214|224,227|230,231|235,239|245,245|247,248|251,252|254,259|263,279|285,288|293,293|296,303|316,318|322,341 Q:1,5|11,12|14,20|22,24|83,83|85,88|90,92|98,98|114,118|131,132|134,137|139,139|150,150|154,157|162,163|170,171|173,174|177,177|181,182|193,195|197,197|200,207|211,211|215,223|228,229|232,234|240,244|246,246|249,250|253,253|260,262|280,284|289,292|294,295|304,315|319,321|342,350 ?EEEEE-----TT?HHHHHHT-TSS-----------------------------------------------------?--??T-TTTT?GGG?-???S?--------------TTTTS-??---------TT?TTTT-T?---------G---GGST----TT???---TT-TS??E---EE----------ESE-E--EEEEEEES-??S--?EEEEEEEEE---?TT??TTS?--??GGGEE?S-?SS?-B?----?SSB-----------??---?SEEEE----EEEE?TT------??EEEEEEEEEEES---SSS?-------------------EEEEEEEEE 2LHS|A PF03068.10_PAD_seed 7 397 !Q:2,3|16,18|20,22|26,26|33,47|58,58|63,75|78,78|95,115|119,129|139,140|152,153|159,159|162,163|166,170|181,181|184,185|190,190|196,197|207,207|235,235|238,238|240,253|261,261|288,289|298,299|303,303|307,311|317,318|322,322|325,325|333,337|358,358|364,379|385,387|390,390|394,397 Q:0,1|4,15|19,19|23,25|27,32|48,57|59,62|76,77|79,94|116,118|130,138|141,151|154,158|160,161|164,165|171,180|182,183|186,189|191,195|198,206|208,234|236,237|239,239|254,260|262,287|290,297|300,302|304,306|312,316|319,321|323,324|326,332|338,357|359,363|380,384|388,389|391,393 SS??EEEEEEEEEEEE???B???TTS?EEEEEE?????----??????SHHHHHHHHT?EEEE?????????????TT?EEEEEEETTEEEEEEE?????????????????????EEE???????????TTSGGGEEE??SEEETTEEETT??EEEEE?SS??SS?????HHHHHHHHHT?TT??EEEE?TTBSS??GGGTEEEEE?SSSTTEEEEEEEHHHHHHHHHHHHHTT?TT?B???????????---BHHHHHH?HHHHHHHHHHHHHHHHHHHHHHHHTT??GGGEEEEE??EEE?GGG----?EEESS??TTS?EE?SSEEEEE?????EETTEEHHHHHHHHHHGGGT?EEEEE????????????????EEEEE???SS?GGG???- 1WD8|A PF03069.10_FmdA_AmdA_seed 8 419 !Q:3,5|9,9|13,13|16,16|22,22|26,27|32,32|35,35|42,43|48,48|50,50|54,58|64,65|69,71|81,87|90,90|101,102|104,110|112,115|122,123|128,129|135,138|164,166|173,173|175,177|198,198|201,201|203,207|211,213|216,217|219,219|229,229|231,231|237,237|243,245|249,249|252,252|258,259|273,275|278,278|287,288|302,302|308,308|310,317|319,319|323,324|326,328|330,335|345,345|348,350|352,352|355,355|376,377|389,390|398,398|402,403|411,411|418,418 Q:0,2|6,8|10,12|14,15|17,21|23,25|28,31|33,34|36,41|44,47|49,49|51,53|59,63|66,68|72,80|88,89|91,100|103,103|111,111|116,121|124,127|130,134|139,163|167,172|174,174|178,197|199,200|202,202|208,210|214,215|218,218|220,228|230,230|232,236|238,242|246,248|250,251|253,257|260,272|276,277|279,286|289,301|303,307|309,309|318,318|320,322|325,325|329,329|336,344|346,347|351,351|353,354|356,375|378,388|391,397|399,401|404,410|412,417 EEE???TTS?GGG?TT-EESSB?TTS??SEEE?TT?EEEEEE??TTSS?S?SSS?---?HHHHH??TTS???EEEEEEETT-----??TT?EEEEEEEEEE??T-------T??--EEEEEE??GGGT??TTTTT--??SEEEEEEEEETTEEEETTEEEEEEE???EEEEEE-E???HHHHHHHHHHHHHHHHTSTT?SS?S?????STT???TT??H-HHHHHHHHH?B?SSSEE-TTEES???TTS?TT?EEEEE??STTEEEEEEEEES???TB?TTEEEEEE??EEEEEEEEEETTH-HHHTT?S--------S?EEE??S?-?B???--?EEEEEEESB?TT?-?B?SS?HHHHHHHHHHHHHHHHHTTT??HHHHHHHHHHS??EEEEEES?STT??EEEEEEE-GGGBSS? 2WKN|A PF03070.11_TENA_THI-4_seed 25 272 !Q:13,15|25,25|27,27|51,53|59,59|66,66|80,84|97,100|103,103|108,111|125,125|130,130|150,179|185,193|195,195|231,231|235,245|265,265|271,271 Q:0,12|16,24|26,26|28,50|54,58|60,65|67,79|85,96|101,102|104,107|112,124|126,129|131,149|180,184|194,194|196,230|232,234|246,264|266,270 STTTHHHHHHHHT--?HHHHHHHTT?S?HHHHHHHHHHHHHHHHHHHHHHH---HHHHH?SSHHHH-HHHHHHHHHHHHH-----HHHHHHHHHHTS????TT-TTTS????HHHHHHHHHHHHH-HHHS?HHHHHHHHHHHHHHHHHHH------------------------------HTTTT???------S?TTSHHHHHHHHTTSHHHHHHHHHHHHHHHHHHTTS?GGG-----------HHHHHHHHHHHHHHHHHHH-HHHHT? 3HNH|A PF03071.10_GNT-I_seed 4 450 !Q:0,99|107,107|110,110|122,123|125,125|130,130|136,136|139,139|158,158|160,170|173,173|198,199|212,212|229,229|238,239|242,242|248,248|251,251|254,254|261,263|280,281|284,284|298,298|306,306|309,310|313,315|320,320|332,335|337,339|344,345|362,362|366,366|368,369|377,378|380,381|383,383|385,385|391,392|406,409|418,418|430,430|437,438|441,443|445,446|449,449 Q:100,106|108,109|111,121|124,124|126,129|131,135|137,138|140,157|159,159|171,172|174,197|200,211|213,228|230,237|240,241|243,247|249,250|252,253|255,260|264,279|282,283|285,297|299,305|307,308|311,312|316,319|321,331|336,336|340,343|346,361|363,365|367,367|370,376|379,379|382,382|384,384|386,390|393,405|410,417|419,429|431,436|439,440|444,444|447,448 -------------------------------------?---??????--------------------------------------------------???EEEEESS?TT-HHHHHHHHHHH?-S?TTTS?EEEEE?TT?HHHHHHHHTTGGGSEEEE?S--????????-TT?GGGHHHHHHHHHHHHHHHHHHHTS??SEEEEEETTEEE?TTHHHHHHHHHHHHHH?TTEEEEES??TT?BGGGS?TT?TT?EEEESS???SSEEEEHHHHHHHGGG??SS?HHHHHTSHHHHTT?EEEEESS?SE--EE???SSSS?SHHHHHTGGGB????S???GGGS??GGGSHHHHHHHHHHHH-HHS?B??HHHHHTT??T--T?S-EEEEE??SHHHHHHHHHHHT????EETTEETT?BTTBEEEEETT-EEEEEE??TT-??S??TT? 1FOA|A PF03074.11_GCS_seed 10 417 !Q:3,3|12,12|45,48|58,59|69,72|79,80|90,90|93,94|101,104|107,107|112,118|122,123|127,128|130,134|144,144|147,150|164,168|175,176|180,181|191,191|193,193|199,201|204,205|208,208|212,213|219,221|223,224|251,256|276,276|283,283|285,300|302,302|305,307|311,313|322,322|324,324|327,327|343,343|346,346|353,353|356,356|359,360|377,378|390,390|393,394|399,400 Q:0,2|4,11|13,44|49,57|60,68|73,78|81,89|91,92|95,100|105,106|108,111|119,121|124,126|129,129|135,143|145,146|151,163|169,174|177,179|182,190|192,192|194,198|202,203|206,207|209,211|214,218|222,222|225,250|257,275|277,282|284,284|301,301|303,304|308,310|314,321|323,323|325,326|328,342|344,345|347,352|354,355|357,358|361,376|379,389|391,392|395,398|401,416 EEE?STHHHHTS?BEEEEEEESSHHHHHHHHHHHTTHHHHHHHHT????EETTEEBSB??SHHHHHHHT????TTTTTS??SSTTTSGGG?TT??GGGGGG????SS?SBSS???????STT??GGG??S?????HHHHHHHHS?SS????HHHHHHHHHHTTS?????BGGGSS??TTT??HHHHHHHTT?B?SEEEE???TT??TT?TTS??EEEEE???B??SSHHHHHHHHHHHHHHHHHHHHTTTT??????HHHHHHHHHHTTBTTHHHH?EEEEES?S----------------S?SS???EEE---EEHHHHHH?T-TT?HHHHTHHHHHHHTTS?SS?GGGGGG?SS?HH--HHHHHHHHHHHHTTSS??HHHHHHHHHHT?TT??SSSB??HHHHHHHHHHHHHHHT 3IG5|A PF03079.9_ARD_seed 11 169 !Q:5,5|7,8|10,11|15,16|18,18|21,22|24,25|34,35|40,41|48,48|60,61|66,75|96,96|99,99|102,102|118,120|124,124|139,139|142,143|149,149|152,153|164,168 Q:0,4|6,6|9,9|12,14|17,17|19,20|23,23|26,33|36,39|42,47|49,59|62,65|76,95|97,98|100,101|103,117|121,123|125,138|140,141|144,148|150,151|154,163 EEEEB?S??S-?TTS??B?SS??B??HHHHHHTT-?EEEE??GGGTTS?HHHHHHHHHHT??EEEE----------EEESTTTSTTHHHHHHHHHS?EE?SS?EEEEEEEEEEEEEEE--?TTS?EEEEEEETTEEEEE?TT??EEEEE?TT??EEEEEEESSS????? 1VR3|A PF03081.10_Exo70_seed 58 619 !Q:1,1|20,20|27,42|44,44|47,49|52,56|66,66|72,76|88,102|129,131|135,137|139,139|142,157|163,172|195,209|213,214|216,218|221,224|239,240|253,254|260,260|263,264|269,289|292,292|316,319|325,325|329,349|351,351|354,354|357,359|361,361|380,381|385,396|398,400|416,418|427,430|448,484|488,488|492,506|514,526|542,542|545,551|568,570|586,590|593,597|601,601|603,605|609,610 Q:0,0|2,19|21,26|43,43|45,46|50,51|57,65|67,71|77,87|103,128|132,134|138,138|140,141|158,162|173,194|210,212|215,215|219,220|225,238|241,252|255,259|261,262|265,268|290,291|293,315|320,324|326,328|350,350|352,353|355,356|360,360|362,379|382,384|397,397|401,415|419,426|431,447|485,487|489,491|507,513|527,541|543,544|552,567|571,585|591,592|598,600|602,602|606,608|611,618 T?STHHHHHHHHHHHHHHHH-HHHHHH----------------S?TT--?TT-----HHHHHHHHH-HHHHH-----HHHHHHHHHHH---------------HHHHTHHHHGGGHHHHHHHHHHHHHH---TTT???S?HH----------------HHHHH----------HHHHHHHHHHHHHHHHHHHHHH---------------HTT??S??-TT????HHHHHHHHHHHHHG--GGHHHHHHHTSS??STTTS?SS??GGGS????-------------????TT?HHHHHHHHHHHHHHHHHHHHHHH----HHHHH?TTS?-----------------???S?TT?SS--?S?HHHHHHHHHHHHHHHHHH--HHT------------S---THHHHTTTHHHHHHH---HHHHHHHH----HHHHHHHHHHHHHHHHH-------------------------------------HTT?SSS??-----------??HHHHHHH-------------HHHHHHHHHHHHHHH-TT???--??HHHHHHHHHHHHHHHH---HHHHHHHHHHGGGSS-----SG-----GGT?S??-HHH--HHHHHHHH 2PFV|A PF03084.9_Sigma_1_2_seed 4 419 !Q:0,0|2,5|9,12|15,15|20,21|30,30|34,34|36,54|58,58|81,81|88,89|100,102|106,107|110,110|113,119|122,122|159,159|166,166|169,169|171,171|184,184|200,203|240,240|248,250|255,256|262,265|267,267|275,275|282,282|300,303|310,310|316,316|324,324|326,326|331,331|350,350|389,392|395,398|404,404 Q:1,1|6,8|13,14|16,19|22,29|31,33|35,35|55,57|59,80|82,87|90,99|103,105|108,109|111,112|120,121|123,158|160,165|167,168|170,170|172,183|185,199|204,239|241,247|251,254|257,261|266,266|268,274|276,281|283,299|304,309|311,315|317,323|325,325|327,330|332,349|351,388|393,394|399,403|405,418 ?B????EEE????BT-TBSS??HHHHHHHS?TTS?S???????????????????SSS?SHHHHHHHHHHHHHHHSTTTTT?TTHHHH??BTTEEESSTT???EEE??SS?SS??-????SS?EEEGGGSHHHHHSHHHHHTTHHHHHHHHHHHHBSSS?EEEEEE?TT?S?HHHHHHHHHTTT?BHHHHHHHHHHHTSS????TTSHHHHHHHHHHHHHHHHHTTSSBTTEEBTTEEEE?SSSSSTT???EEEE?-SSSEE????S?EEEEEEE?SGGGGG?HHHHHHHHHHHHHHHTB????EEGGGB?GGGTT?TTTEETT?B?EEEE?HHHHHHHHHHHHHHTTSS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTT???-SS????GGGGS?TTHHHHHHHHHGGG 2CSE|X PF03088.11_Str_synth_seed 8 90 !Q:5,5|9,10|16,17|20,21|23,23|25,25|34,36|58,60|65,65 Q:0,4|6,8|11,15|18,19|22,22|24,24|26,33|37,57|61,64|66,89 EEEEE?TTT??EEEEE??SS??T-T?HHHHHHHT???EEEEEEETTTTEEEEEEEEES???EEEE?TTSSEEEEEEGGGTEEEEEESSST 4HHO|A PF03091.10_CutA1_seed 13 102 !Q:26,26|73,73|78,79|85,86|89,89|101,101 Q:0,25|27,72|74,77|80,84|87,88|90,100 EEEEEEEESSHHHHHHHHHHHHHTTS?SEEEEEEEEEEEEEETTEEEEEEEEEEEEEEEGGGHHHHHHHHHHH?SSSS??EEEEE??EE?HHHHHHHHHTT? 1P1L|A PF03095.10_PTPA_seed 53 501 !Q:0,7|9,9|38,39|42,53|56,57|59,101|109,109|121,147|159,169|180,180|183,201|216,217|219,219|227,227|235,235|247,262|264,265|269,277|279,291|316,316|319,321|323,323|325,325|331,331|345,345|348,374|380,380|385,393|395,395|401,401|411,411|418,424|426,426|431,431|442,443|450,465|478,478|486,488|490,490|493,500 Q:8,8|10,37|40,41|54,55|58,58|102,108|110,120|148,158|170,179|181,182|202,215|218,218|220,226|228,234|236,246|263,263|266,268|278,278|292,315|317,318|322,322|324,324|326,330|332,344|346,347|375,379|381,384|394,394|396,400|402,410|412,417|425,425|427,430|432,441|444,449|466,477|479,485|489,489|491,492 ????????T-TTTHHHHSSHHHHHHHHHHHHHHHTTTT??TT---------???SS??H-------------------------------------------HHHHHHH-HHHHHHHHHTT???---??????-???------?---?THHHHHHHHHH-----------HHHHHHHHHH?TT-----------------??HHHHHHHHHHHHTS--S?BTTTTEE?HHHHHHH-HHHHHHHHHTT----------------S??HHH---------H-------------HHHHHHTHHHHHHHHHHHHHHHHT?EE???S?S?SSSSS?SHHHHHHHHHTTT?SS-??------------------------GGGGG?HHHH---------H-HHTTT?HHHHHHHHH-HHHTTT-------S?HHHH?HHHHHHTTSS-?HHHHHH----------------HHHHHHHHHTTT?HHHHTTS???S-SS???????? 2IXM|A PF03096.9_Ndr_seed 10 303 !Q:17,19|21,22|25,25|31,32|35,36|48,48|59,59|65,65|68,68|72,76|79,83|100,102|122,122|134,136|138,140|151,157|162,162|173,173|180,183|185,185|187,189|201,201|217,223|229,235|237,238|240,240|249,249|263,263|275,275|278,278|283,283|301,302 Q:0,16|20,20|23,24|26,30|33,34|37,47|49,58|60,64|66,67|69,71|77,78|84,99|103,121|123,133|137,137|141,150|158,161|163,172|174,179|184,184|186,186|190,200|202,216|224,228|236,236|239,239|241,248|250,262|264,274|276,277|279,282|284,300 EEEEEETTEEEEEEEES???T--TS?EEEEE??TT??HHHHTHHHHHS-HHHHHHHTTS?EEEEE?TT?STT?????TT?????HHHHHTTHHHHHHHHT???EEEEEETHHHHHHHHHHHH?GGGEEEEEEES???S???HHHHHHHHHH-------HTTS?HHHHHHHHHS?HHHHHH----T?H---HHHHHHHHHHT?TTHHHHHHHHHHHHT???????TTSSS-------S??S?EEEEEETT?TTHHHHHHHHHHS?TTSEEEEEETT?TT?HHHH?HHHHHHHHHHHHHHTTB?? 2XMR|A PF03097.13_BRO1_seed 70 797 !Q:0,8|10,17|30,32|40,42|44,48|60,63|70,78|87,110|126,132|135,135|138,151|155,155|157,157|160,186|190,191|195,195|202,204|228,238|240,242|244,244|264,267|276,282|288,290|292,295|297,298|313,338|352,354|356,371|373,374|381,387|400,408|415,476|490,495|509,545|550,550|555,561|563,597|600,630|643,666|673,675|693,701|707,712|717,736|738,739|742,754|756,761|767,768|776,781|797,797 Q:9,9|18,29|33,39|43,43|49,59|64,69|79,86|111,125|133,134|136,137|152,154|156,156|158,159|187,189|192,194|196,201|205,227|239,239|243,243|245,263|268,275|283,287|291,291|296,296|299,312|339,351|355,355|372,372|375,380|388,399|409,414|477,489|496,508|546,549|551,554|562,562|598,599|631,642|667,672|676,692|702,706|713,716|737,737|740,741|755,755|762,766|769,775|782,796 ?????????B?--???--SSHHHHHHHHHH???SSSGGGT---T-----TTTHHHHHHHH----HHHHSS?------??SSSHHHHH------------------------HHHHHHHHHTTGGGS--?----SS?SS-?---------???EEE-E?SS---------------------------SSS??SSS?SEEEES?--HHHHHHHHHHHHHHHHHHHHHHS----------?S---S-SHHHHHHHHHHHHHHHHHH----HHHHTTHH-------HHSSS???S----T--TSHHHHHHHHHHHH--------------------------HHHHHHHHHHHHH---T----------------T??HHHHHH-------HHHHHHHHHHHH---------HHTTTT???-------------------------------------------------??--------TTHHHHHHHHHHH------HHHHHHHHHHHHH-------------------------------------HHTT?HHHH-------H-----------------------------------HH-------------------------------HHHHHHHHHHHH------------------------HHSTTT???HHHHHHHHHHHHHHHHH---------HHHTT??????GGGS?---???-????????-???S??SS-------------S---???TTTTS??HHHHHHH------HHHHHHHHHHHHHHH- 3C3Q|A PF03098.10_An_peroxidase_seed 123 1227 !Q:1,2|5,5|11,12|16,16|20,22|27,27|29,29|31,31|33,38|44,45|52,58|63,77|81,81|83,84|90,94|96,97|99,119|121,121|127,130|139,139|147,150|152,156|159,164|174,184|189,194|197,198|201,201|208,214|218,219|221,221|223,223|227,228|232,242|245,255|257,286|289,289|291,291|294,294|296,296|301,301|312,314|319,325|327,332|335,336|338,338|342,348|350,356|359,360|367,374|378,381|383,384|416,428|430,452|455,546|550,551|564,587|589,589|592,624|636,636|639,643|650,731|735,738|743,743|754,755|760,760|762,762|766,783|785,785|787,794|797,797|800,802|807,807|810,811|813,814|820,842|844,844|848,850|853,853|859,895|900,901|904,904|907,907|909,909|915,915|917,923|927,933|935,935|937,938|949,949|953,955|965,975|984,992|995,995|999,1027|1036,1070|1076,1077|1086,1089|1091,1091|1094,1107|1110,1110|1114,1119|1134,1134|1137,1137|1139,1142|1144,1146|1149,1160|1162,1174|1176,1176|1178,1178|1187,1191|1193,1195|1204,1208|1210,1210|1212,1216|1218,1219|1223,1223 Q:0,0|3,4|6,10|13,15|17,19|23,26|28,28|30,30|32,32|39,43|46,51|59,62|78,80|82,82|85,89|95,95|98,98|120,120|122,126|131,138|140,146|151,151|157,158|165,173|185,188|195,196|199,200|202,207|215,217|220,220|222,222|224,226|229,231|243,244|256,256|287,288|290,290|292,293|295,295|297,300|302,311|315,318|326,326|333,334|337,337|339,341|349,349|357,358|361,366|375,377|382,382|385,415|429,429|453,454|547,549|552,563|588,588|590,591|625,635|637,638|644,649|732,734|739,742|744,753|756,759|761,761|763,765|784,784|786,786|795,796|798,799|803,806|808,809|812,812|815,819|843,843|845,847|851,852|854,858|896,899|902,903|905,906|908,908|910,914|916,916|924,926|934,934|936,936|939,948|950,952|956,964|976,983|993,994|996,998|1028,1035|1071,1075|1078,1085|1090,1090|1092,1093|1108,1109|1111,1113|1120,1133|1135,1136|1138,1138|1143,1143|1147,1148|1161,1161|1175,1175|1177,1177|1179,1186|1192,1192|1196,1203|1209,1209|1211,1211|1217,1217|1220,1222|1224,1226 S??TT?TTSSS--SSS-STT--?SSEE?B?S-S????--TTSSS??TTSSTT?-----?BTTB????-----------HHH-H--HHHHT---??S??T---------------------T?EEEEE----EHHHHHHH-HHHHHHH????B??-??SS?-----GGGTTTTSS?--------??BTTB??----EE??TT?THHHHT?------SEE??B?B?BSS?-SSS?---------?SS--------???B------------------------------EE?S?SS?S?HHHH?SSHHHHHHTB?-?SSTT-----??B??---?SS??B-TTB?---???B??----?SS-?HHHHTT--------TTT????B??SSTTTTSBHHHHHHHHHHHHHHHHHHHHHHH-------------H----------------------?TT------------------------------------------------------------------------------------------??HHH--HHHHHHHHHHHH------------------------H-HH---------------------------------HHHHHTSTTTS-GG-----GHHHHS?-------------------------------------------------------------????--------------??TTS????BTTH-HHHGGGGGGT??SEEE?B?TTS-----------------?B?S--------SS?EE---EGGG?BT??H--HHHTT-----------------------T?SHH---HH-HHHHH-------------------------------------SEEE??BT-TB?S?HHHHT?B--?---?TTS??-----S?B-?HHHHHHHHHH-HTT???HHHHHHHTT------?????SHHHHHHH---------HT?HHH-----------------------------HHHHHHHH-----------------------------------SSGGG??HHHHHTTS???-T-TS--------------SS?HHH------HHHHHHHHHHHHHT?TT?T----T---ST------------T-------------S-S?HHHHHHHT-----T?-?HHHHHHHT-----S-S?---?E--EES-SSS 2IPS|A PF03099.14_BPL_LplA_LipB_seed 66 186 !Q:5,5|7,7|11,15|19,22|25,27|30,30|36,36|40,40|42,42|44,44|47,47|49,52|55,55|64,71|75,75|79,80|90,90|94,114|119,121|123,124|127,127|135,146|152,153|161,166|169,175|185,185 Q:0,4|6,6|8,10|16,18|23,24|28,29|31,35|37,39|41,41|43,43|45,46|48,48|53,54|56,63|72,74|76,78|81,89|91,93|115,118|122,122|125,126|128,134|147,151|154,160|167,168|176,184 EESSB-S?HHH-----HHH----HS???TT?EEEES?BSS?B?S-TT?B????TT-SEEEEEEE????---?STT?TTH--HHHHHHHHH-HHH---------------------HHTT???E--EE-TTTEEEE------------TTEEE--EEEEEEE------ET-------TEEEEEEEE? 3FJP|A PF03100.10_CcmE_seed 135 180 !Q:0,33|37,38|40,40|47,47|50,51|55,59|71,71|75,75|78,78|80,80|87,87|91,91|93,93|95,97|99,108|110,110|118,120|123,124|134,149|152,153|157,160|167,167|169,170|172,177 Q:34,36|39,39|41,46|48,49|52,54|60,70|72,74|76,77|79,79|81,86|88,90|92,92|94,94|98,98|109,109|111,117|121,122|125,133|150,151|154,156|161,166|168,168|171,171|178,179 -------------------------------???SSS??B?TTTTTS?ST--TTS????-TTSEEEEEEEE?TTT?EE?S-SSSEEE-EEE-E?S---S---------?E-EEEEEES???TT??TTSEEEEEE----------------EE-?SSS----EEEESS?B??S??????HH 1SR3|A PF03102.9_NeuB_seed 158 319 !Q:7,7|10,10|18,19|24,25|28,29|33,48|51,51|54,54|63,66|82,82|89,89|98,98|103,103|105,105|109,109|115,115|125,127|129,129|131,136|141,141|144,145|157,184|189,190|196,199|202,203|207,211|222,225|228,228|232,232|236,237|240,242|255,256|258,267|273,273|275,275|278,283|290,292|294,294|313,316 Q:0,6|8,9|11,17|20,23|26,27|30,32|49,50|52,53|55,62|67,81|83,88|90,97|99,102|104,104|106,108|110,114|116,124|128,128|130,130|137,140|142,143|146,156|185,188|191,195|200,201|204,206|212,221|226,227|229,231|233,235|238,239|243,254|257,257|268,272|274,274|276,277|284,289|293,293|295,312|317,318 HHHHHHH-HT?SEEEEEE??HHHH??GG--GGG??-------------?TT?SS?HHHHHHHH?-??HHHHHHHHHHHHHTT?EEEEEE?SHHHHHHH-HHHT?S?EEE?GGGTT?HHHHHHHHT---T?S?-----EEEE?TT??HHHHHHHHHHH----------------------------HHHT??EEEEE????SS??GGG---??TTHHHHHHHH?---TT-SEE-EEE??SS---SSHHHHHHHHTT??E----------EEEEB?S?TT?----?STTGGG?--B?HHHHHHHHHHHHHHHHHS-???TT 1VS1|A PF03104.14_DNA_pol_B_exo1_seed 32 535 !Q:5,5|14,16|22,23|30,30|35,65|79,79|89,101|106,107|109,109|111,112|114,114|129,133|143,145|147,148|155,158|160,196|206,206|208,209|212,212|217,217|222,239|242,243|247,248|250,251|262,262|266,266|273,278|288,290|294,301|305,306|319,342|345,345|355,358|361,388|396,397|415,416|441,441|444,444|446,447|453,456|458,459|467,489|496,497|499,500|503,503|516,526|528,530 Q:0,4|6,13|17,21|24,29|31,34|66,78|80,88|102,105|108,108|110,110|113,113|115,128|134,142|146,146|149,154|159,159|197,205|207,207|210,211|213,216|218,221|240,241|244,246|249,249|252,261|263,265|267,272|279,287|291,293|302,304|307,318|343,344|346,354|359,360|389,395|398,414|417,440|442,443|445,445|448,452|457,457|460,466|490,495|498,498|501,502|504,515|527,527|531,534 EETTS?EEEEEEES???EEEEE??SSGGGG?HHHH-------------------------------HHHHHHHHTTTTT?EEEEEEEEE-------------EESS??S?S??E-EEEEEEESSTTHHH-----HHHHHHHHS???G--GGSSTT????B---------------------------------????HHHHHHHHH-T??TT?EEEE?TTSE------------------EE??GGG??B??SEEEEEETTT?EEE?SSGGGS-?????EEEEEEEEE???TTS---??--?TTT??EEEEEEEEEETT-----------------------?SS?SEEEEEEES????BT----------------------------TBEEEEE--SSHHHHHHHHHHHHHHH??SEEEESSTTTTHHHHHHHHHHHTT?TT?S??SSBTT????B??EEEEETT-----------------------TEEEEE??B??TT?EEEEHHHHHHHH?--------??S???HHHH 3K5N|A PF03106.10_WRKY_seed 34 63 !Q:0,2|5,5|13,14|17,17|20,20|27,27|30,32|34,36|43,43|57,58|61,62 Q:3,4|6,12|15,16|18,19|21,26|28,29|33,33|37,42|44,56|59,60 ???SS?EEEEEEE??TT?SS?EEEEEE?ST---T???EEEEEE?SSSTTEEEEEEES??SS?? 2AYD|A PF03110.9_SBP_seed 30 81 !Q:0,1|6,10|13,15|23,24|30,30|32,32|35,35|44,44|56,57|60,61|63,63|69,75|77,80 Q:2,5|11,12|16,22|25,29|31,31|33,34|36,43|45,55|58,59|62,62|64,68|76,76 ??SSTT?????TT?-?HHHHHTT??HHHHT?S?EE-ETTEEEEE?TTTSSEEETTT??SS??S?STTTT???????S???? 1UL4|A PF03114.13_BAR_seed 28 277 !Q:0,29|58,59|70,84|86,87|104,104|109,110|113,122|136,136|191,212|246,246 Q:30,57|60,69|85,85|88,103|105,108|111,112|123,135|137,190|213,245|247,276 ????----???????????????????-??HHHHHHHHHHHHHHHHHHHHHHHHHHHH??STTTHHHHTT???????????????S??HHHHHHHHHHHHHHHH?SSSS--HH----------HHHHHHHHHHHHH-HHHHHHHHHHHHHHTHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHTTTTS?---------------------HHHHHHHHHHHHHHHHHHHHHHHHHHHTTHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 1URU|A PF03118.10_RNA_pol_A_CTD_seed 121 73 !Q:0,6|9,11|15,15|21,22|35,36|44,45|55,55|63,65 Q:7,8|12,14|16,20|23,34|37,43|46,54|56,62|66,72 ???-?--SS???GGG?BGGGS??BHHHHHHHHHTT??BHHHHTT??HHHHTTSTT?HHHHHHH---HHHHHHH 4KN4|A PF03119.11_DNA_ligase_ZBD_seed 152 36 !Q:1,1|5,6|10,10|12,12|15,20|22,23|27,28|30,30|33,33 Q:0,0|2,4|7,9|11,11|13,14|21,21|24,26|29,29|31,32|34,35 B?TTT??BEE-E?TT-----?S-?EEE??G-GG?HH 1DGS|A PF03120.11_DNA_ligase_OB_seed 23 85 !Q:12,12|17,17|39,40|50,51|54,54|72,72|74,75|78,79|82,82|84,84 Q:0,11|13,16|18,38|41,49|52,53|55,71|73,73|76,77|80,81|83,83 EEEEEEEEEEEE?TTSB-EEEEEEEEEEEETTEEEEEEE??SHHHHHHHT??BT?EEEEEEETTTEEEEEEE?G--GG??SS?B? 1DGS|A PF03122.9_Herpes_MCP_seed 32 1518 !Q:0,513|517,524|526,526|546,547|550,574|577,577|581,583|586,587|590,591|594,598|600,603|607,609|615,615|620,620|634,635|638,643|656,656|659,660|671,671|673,673|697,698|703,703|714,714|716,716|720,720|746,746|748,750|754,754|756,756|766,766|770,771|774,774|777,778|789,791|795,798|804,806|811,813|817,818|821,823|825,825|829,832|836,837|840,841|845,845|848,848|850,858|879,880|886,886|895,897|899,932|936,940|944,944|954,955|968,972|977,977|987,992|999,1000|1003,1003|1006,1014|1027,1027|1029,1031|1045,1046|1053,1053|1056,1057|1065,1066|1077,1089|1093,1094|1101,1101|1109,1112|1115,1118|1132,1133|1146,1517 Q:514,516|525,525|527,545|548,549|575,576|578,580|584,585|588,589|592,593|599,599|604,606|610,614|616,619|621,633|636,637|644,655|657,658|661,670|672,672|674,696|699,702|704,713|715,715|717,719|721,745|747,747|751,753|755,755|757,765|767,769|772,773|775,776|779,788|792,794|799,803|807,810|814,816|819,820|824,824|826,828|833,835|838,839|842,844|846,847|849,849|859,878|881,885|887,894|898,898|933,935|941,943|945,953|956,967|973,976|978,986|993,998|1001,1002|1004,1005|1015,1026|1028,1028|1032,1044|1047,1052|1054,1055|1058,1064|1067,1076|1090,1092|1095,1100|1102,1108|1113,1114|1119,1131|1134,1145 ---?----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------???-----------------------------------------------------------------------------??????????????????????---?-----?????--------------?-??GGG????--??S?HHHHHHHHHTTSHHHHHSS??SS????????????????-????????TT?EEE???SS??TT??SS?--??S????EEE???SGGGS?TTTS?HHHHHHHHHHHHT--TS???--?HHHHHHHHHHHH?TT??THHHHHHHHS?S?HHHHHHTHHHHHHHHHHHHHHSS??SSTT?HHHHHHHHHS?G-GGS?HHHHHHHHHHHHHHHHHHHHHHHTS?S???GGG-S?HHHHHBSTT?TTS??SB?SS--SHHHHHHHSS?--TTT????EETTB?-?EEES???SSS??TT-??S?EEE????SSS--SS??SSS?SS?H---------HHHHHHHHHHHTHHHHHHTT??EEEEE?HHHHHHHH---T??----------------------????----??TTS?????TTT?TTSTTSGGG??TTSHHHHHHHTT??-??HHHH-HGGGGGGTS??????EEEEEE??SS?SS?????-???EEEEEESSEEEE?S???TTSTTTTTSSEEE??SBTTBB?HH--HHHTSTT??TTTHHHHTSS??---------??GGG??GGGSSS?HHHHHHH----HH????HHHHHHHHHHHTB??SHHHHHHHHHHT???????????------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1NO7|A PF03123.10_CAT_RBD_seed 15 62 !Q:15,16|20,20|26,26|33,34|37,37|41,43|47,48|52,52|56,56 Q:0,14|17,19|21,25|27,32|35,36|38,40|44,46|49,51|53,55|57,61 EEEEEEEETTEEEEE-?GGG?EEEEE?TTTTTT??TT?EEE?-?SSS??EEE?SHH-HHHHH 1AUU|A PF03126.13_Plus-3_seed 39 124 !Q:7,8|20,20|29,29|37,42|44,48|62,63|69,75|91,92|103,103|106,108|117,117 Q:0,6|9,19|21,28|30,36|43,43|49,61|64,68|76,90|93,102|104,105|109,116|118,123 HHHHTTB??HHHHHHHTTST-THHHHHTT?EEEEEEE??????E-----EEEEEEEEEEEEE--EEEEE-------TTEEEEEEEEEEETT--EEEEEEGGGB?SS???HHHHHHHH-HHHHHH 3U1U|A PF03127.9_GAT_seed 33 145 !Q:10,10|31,31|35,36|42,45|49,71|89,97|100,102|105,106|133,145 Q:0,9|11,30|32,34|37,41|46,48|72,88|98,99|103,104|107,132 SSSTTHHHHH-HHHHHHHHHHHHHHHHHHHS?TTT??HHHHH----HHH-----------------------HHHHHHHHHHHHHHHHH---------HH???HH--HHHHHHHHHHHHHHHHHHHHHHHHHH??-??----???- 1WR6|A PF03129.15_HGTP_anticodon_seed 116 149 !Q:7,7|10,18|23,27|42,54|57,57|61,64|66,66|69,70|81,81|88,88|93,94|96,97|100,102|106,107|116,119|122,124|126,130|132,133|144,144 Q:0,6|8,9|19,22|28,41|55,56|58,60|65,65|67,68|71,80|82,87|89,92|95,95|98,99|103,105|108,115|120,121|125,125|131,131|134,143|145,148 SEEEEES?SS--------?HHHH-----HHHHHHHHHHHTTT-------------SS?EEE?-??S?HH--HHHHHHHHTT?SEEEEE?HHHH--T??TT???SST--TEEEEEET----TT?-?E-----E--EEEHHHHHHH-HHHH 2Q5I|A PF03130.11_HEAT_PBS_seed 221 40 !Q:12,26|39,39 Q:0,11|27,38 HHHHHHHHHHHH??-------------GGGHHHHHHHTT? 3LTM|A PF03131.12_bZIP_Maf_seed 15 95 !Q:0,1|9,9|18,20|23,24|89,95 Q:2,8|10,17|21,22|25,88 ??HHHHHHS?HHHHHHTT---TT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTSSTTTTTTSTTSHHHHTTTSSSS??????- 1S9K|D PF03133.10_TTL_seed 21 409 !Q:3,3|7,11|14,14|18,19|24,76|92,107|112,121|126,126|136,179|185,186|190,191|195,198|212,215|218,219|225,227|236,245|248,248|252,252|256,258|266,268|270,270|295,295|297,298|318,324|330,331|339,339|349,356|360,361|371,377|395,397|401,408 Q:0,2|4,6|12,13|15,17|20,23|77,91|108,111|122,125|127,135|180,184|187,189|192,194|199,211|216,217|220,224|228,235|246,247|249,251|253,255|259,265|269,269|271,294|296,296|299,317|325,329|332,338|340,348|357,359|362,370|378,394|398,400 HHH?TTT----?TT?SSS??EEEE????-??????????????????-------------------------?????HHHHHHHHHHHHHHT??------------??EEEE??????????EEES?HHHHHHHHH-------------------------------?--------????EEEEE??SSB??BTT----TTEEEEEEEEEEE?---TT??EEEES??-EEEEEEEE??--------TT?SSS?TTT???HHHHTTT?--T-TTTSSSSSSEEEHHHHHHHHHHHH-S??HHHHTHHHHHHHHHHHHHH-------SHHHH??TTSSSEE?EEEEEEEEE--------BTT??EEEEEEESS?---???GGGHHHHHHHHHHHHTT---TTS???????? 3TII|A PF03136.10_Pup_ligase_seed 31 725 !Q:0,2|9,9|13,13|16,16|19,20|33,119|123,123|127,127|133,136|140,149|154,156|187,201|205,205|209,209|213,214|216,217|223,339|346,346|348,348|367,369|373,380|386,386|390,392|396,396|402,404|408,411|414,416|420,438|441,441|451,456|478,481|484,490|492,494|496,505|518,518|520,520|522,524|532,532|559,567|587,587|590,600|606,606|622,629|631,633|636,639|652,652|657,657|667,667|669,670|673,673|683,685|702,704|708,714|718,718 Q:3,8|10,12|14,15|17,18|21,32|120,122|124,126|128,132|137,139|150,153|157,186|202,204|206,208|210,212|215,215|218,222|340,345|347,347|349,366|370,372|381,385|387,389|393,395|397,401|405,407|412,413|417,419|439,440|442,450|457,477|482,483|491,491|495,495|506,517|519,519|521,521|525,531|533,558|568,586|588,589|601,605|607,621|630,630|634,635|640,651|653,656|658,666|668,668|671,672|674,682|686,701|705,707|715,717|719,724 ???EEEEEE?EEE?TT?SS??HHHHHHHHHHHS????----------??????????????????????--??????-??????-?????--------------------------????EEE?TTS?EEEEE----TTE----------EEEE???BSSHHHHHHHHHHHHHHHHHHHHHHHHSSS?-----------???EEE?SSB?SSS-?B??EEEEE---------------------------------------------------------------------------------------------------------------------EEETTS?H-HHHHHHHHHHHHHTHHHH???EEE--------ETTTS?EEE---EES?SSGGG???SEE???-SS???SEE???--------------??SS?TTTEEEEEE??????SSHHHHHHHHHHHHHHHHHHH----TT??----?S???B----------SSHHHHHHHHHH?T-T???EEEBTTS?EEEHHHHHHHHHHHHHHHHHHHTGGG-------??HHHHHHHHHHHHHHHHHHH?SG-----------GGTTT?HHHHHHHHHHHHHHH--------H???TT?---HHHHHHHHHHTB?STTT?HHHHHHHTT?S??SS?HHHHHHHHH???SSSTHHHHHHHHHHHG---GGE-------EEE?SSEEEE 4BJR|A PF03143.12_GTP_EFTU_D3_seed 82 119 !Q:1,1|14,15|20,21|24,24|26,26|29,31|35,35|38,39|43,43|47,57|60,68|70,70|73,73|84,84|89,89|92,98|118,118 Q:0,0|2,13|16,19|22,23|25,25|27,28|32,34|36,37|40,42|44,46|58,59|69,69|71,72|74,83|85,88|90,91|99,117 S?EEEEEEEEEEEE??TTTT??SS?B?TT???EEE?TT??EEE-EEE?---------?TT?------??B?TT?EEEEEEEEEE-EEEE?TT?------EEEEEETTEEEEEEEEEEE? 2HDN|B PF03144.20_GTP_EFTU_D2_seed 305 110 !Q:16,16|27,27|30,43|55,55|57,57|61,81|85,85|94,95|99,103|106,106 Q:0,15|17,26|28,29|44,54|56,56|58,60|82,84|86,93|96,98|104,105|107,109 EEEEEEEEEESEEETT?EEEEESSSSS?EE--------------EEEEEEESSSS-B?SEE---------------------ETT?EEEEEESS??GGG---??TT?EEE 1N0V|C PF03145.11_Sina_seed 10 243 !Q:0,14|17,17|24,26|28,28|30,30|41,41|45,45|48,49|53,54|57,59|62,62|74,74|77,77|84,84|91,92|95,96|106,133|148,155|166,166|182,183|193,194|200,200|209,214|227,227|232,236 Q:15,16|18,23|27,27|29,29|31,40|42,44|46,47|50,52|55,56|60,61|63,73|75,76|78,83|85,90|93,94|97,105|134,147|156,165|167,181|184,192|195,199|201,208|215,226|228,231|237,242 ------?????????EE?GGGGGT???E-E?GGGHHHHHHH?TTS?EE??SSS--SS???EE?HHHHHHHHHHH?TT?EEEESS-EEEEEE??TT??SSEEEEEEE----------------------------EETTEEEEEEEEEE???-????EEEEEEEESS?HHHHTTEEEEEEEEE--TTEEEEEEE??EETTT?SHHHHHTT-----?SEEEEHHHHHHH?BTTB-----EEEEEE 2AN6|A PF03146.10_NtA_seed 2 128 !Q:0,5|13,13|46,46|54,56|69,69|75,78|81,81|90,91|101,101|105,105|107,108|110,112 Q:6,12|14,45|47,53|57,68|70,74|79,80|82,89|92,100|102,104|106,106|109,109|113,127 ??????HHHHHHT?SEEEEEEEEEEEEEETTTTEEEEEEEEEEEEE?HHHHHHH???BTTTEEEEEEET?TTSSS????TT?EEEEEEEE??GGGTTTTTT?EEE?S??B???HHHHHHHHHHHHHHH 1JC7|A PF03147.9_FDX-ACB_seed 134 142 !Q:0,1|3,4|8,8|17,34|37,38|41,44|48,49|57,62|65,65|69,69|74,76|78,79|81,90|94,95|97,98|110,111|114,117|137,138|140,141 Q:2,2|5,7|9,16|35,36|39,40|45,47|50,56|63,64|66,68|70,73|77,77|80,80|91,93|96,96|99,109|112,113|118,136|139,139 ??S??EEE-EEEEEEET------------------TS-?HH----HHH--TTTSSTT------TT-TEE-EEEE???B?-S----------TTS?-T--TEEEEEEEEEE??SS????HHHHHHHHHHHHHHTTTTT??B?? 2IY5|B PF03150.9_CCP_MauG_seed 173 414 !Q:0,0|4,4|14,14|21,27|29,31|38,38|41,50|52,53|57,59|64,72|75,79|82,82|84,100|103,110|113,118|122,122|126,175|178,178|183,213|215,216|218,219|221,221|224,239|244,279|285,285|291,303|306,311|322,357|359,359|361,366|368,370|382,382|386,394|401,405|408,409 Q:1,3|5,13|15,20|28,28|32,37|39,40|51,51|54,56|60,63|73,74|80,81|83,83|101,102|111,112|119,121|123,125|176,177|179,182|214,214|217,217|220,220|222,223|240,243|280,284|286,290|304,305|312,321|358,358|360,360|367,367|371,381|383,385|395,400|406,407|410,413 ?HHH-HHHHHHHHH?GGGSTT-------S???HHHHSB-TT----------T--TTB?--SSSS-------?-EE-----GG-G-----------------EE-------?SS--????STT-GGG??--?-------------------------------------------?-SS-EEEH-------------------------------H--H--H-TT??------????--??HHHH------??---?------------------------HHHHH-HHHHT?------------HH------HHHHHHHHST------------------------------------T?S------S???HHHHHHHHHHH-HTT?---?????HHHHHH-----TT-?GGGS 3RN1|A PF03152.9_UFD1_seed 37 245 !Q:1,1|9,9|18,19|21,22|32,33|43,46|49,53|56,56|62,64|67,74|87,89|96,97|100,123|130,131|136,140|145,145|148,152|167,168|171,171|176,176|182,182|185,186|189,189|192,192|201,201|211,215|220,223|227,227|230,237|242,245 Q:0,0|2,8|10,17|20,20|23,31|34,42|47,48|54,55|57,61|65,66|75,86|90,95|98,99|124,129|132,135|141,144|146,147|153,166|169,170|172,175|177,181|183,184|187,188|190,191|193,200|202,210|216,219|224,226|228,229|238,241 S?EEEEEEE?STTSSSSS??S--TTTTTTEEE??HHHHHHHHH----TT?--?-SS?EEEEE---ET--------TTTEEEEEEEEE???BTTBEE??SH------------------------HHHHHT??TTEE-----EEEE-EE?????SEEEEEESSHHHHH--SS?HHHH-HHHHH-TT??EE?TT?EEEEESSS?EEEEEEEEE-----SSSS----SEE?SS??-----?EEEE??-- 1ZC1|A PF03153.8_TFIIA_seed 31 717 !Q:7,7|22,22|24,25|47,48|55,648|650,657|662,662|671,681|700,700|703,703|716,716 Q:0,6|8,21|23,23|26,46|49,54|649,649|658,661|663,670|682,699|701,702|704,715 HHHHHHH-HHHHHHHHHHHHHH-T??HHHHHHHHHHHHHHHHHHTSS??TTGGGG--???????-----------------------------------------------------?????????????????????????-----------------??????----????????????????????-----------------???????????????????????????????????????-----------------------------------------????????????????????----------------------------------?????????----------------------------------------------------?????????------??????????????------------------------------------------------------------------------------------------------------------------------------------------------------------???---??-???---------------------------------------????????????B-???????STTS?EEEEEEEE-----------EEEETTEEEEEEEEEEEE?SS?EEEEEEEEEEEE? 1NH2|B PF03159.13_XRN_N_seed 17 329 !Q:0,1|13,13|20,25|28,28|32,32|35,38|42,43|48,48|66,66|70,75|80,84|101,101|110,115|152,153|155,155|161,195|220,247|252,252|257,257|259,259|265,265|269,269|271,271|286,286|291,291|294,295|300,302|314,314|316,319|327,328 Q:2,12|14,19|26,27|29,31|33,34|39,41|44,47|49,65|67,69|76,79|85,100|102,109|116,151|154,154|156,160|196,219|248,251|253,256|258,258|260,264|266,268|270,270|272,285|287,290|292,293|296,299|303,313|315,315|320,326 ??HHHHHHHHHHH?GGGEEE??????EE?TTS?EE??-?TTS??TTSS?EEEEEEETHHHHHHHHS?SSS--????SHHH-----HHHHHHHHHHHHHHHH?EEEEEEEE??????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT??B?HHHHS------------------------------?????GGGSSTTSHHHHHHHHHHHHHHHH----------------------------HHTS?GGGT-T?EEEEE?TTS?S?HHHHHHHHHHHHHT-STTS?TT??EEEE???TTHHHHHHHTT?S----SEEEEEE?? 2Y35|A PF03160.9_Calx-beta_seed 32 126 !Q:0,13|21,21|27,28|35,35|45,45|47,47|51,51|61,61|64,67|69,69|71,72|77,81|88,88|91,93|95,95|102,102|104,110|112,117 Q:14,20|22,26|29,34|36,44|46,46|48,50|52,60|62,63|68,68|70,70|73,76|82,87|89,90|94,94|96,101|103,103|111,111|118,125 ??????---?-???EEEEEES?SEEEE--ETTSSE-EEEEEEEES-S?TTS?EEEEEEEEE-SS----S?B--TTTB--???EEEEEE?TT-??E-EEEEEE-B----???S?????-EEEEEEEE 3FQ4|A PF03161.8_LAGLIDADG_2_seed 18 231 !Q:12,12|16,16|19,20|24,31|40,45|58,59|62,63|65,68|75,88|92,92|101,103|105,105|118,120|125,131|138,139|141,142|158,159|162,167|169,173|177,178|182,182|198,200|208,214|222,222 Q:0,11|13,15|17,18|21,23|32,39|46,57|60,61|64,64|69,74|89,91|93,100|104,104|106,117|121,124|132,137|140,140|143,157|160,161|168,168|174,176|179,181|183,197|201,207|215,221|223,230 HHHHHHHHHHTT?EEE?SS--SSS?-------BEEEEEES?-----HHHHHHHHHHTG--GG??S??--EEEEEE-------------?SSS?EEEEEEEE???B-GGGHHHHGGGEE---TTEE----???TTHHHH--H??HHHHHHHHHHHEEES??ST------T?????EEE??TTS?HHHHHHHHHHHHHHH???EEEEEET-------TEEEEEE?GGGHHHHH 3C0X|A PF03162.8_Y_phosphatase2_seed 8 185 !Q:0,3|6,6|9,9|12,14|21,23|33,33|35,37|42,43|46,48|54,55|62,62|66,73|76,87|89,92|105,105|109,109|115,115|131,131|137,137|150,150|152,155|165,184 Q:4,5|7,8|10,11|15,20|24,32|34,34|38,41|44,45|49,53|56,61|63,65|74,75|88,88|93,104|106,108|110,114|116,130|132,136|138,149|151,151|156,164 ????TT?EE?SS---SEEEES???HHHHHHHTT-S???EEEE??SS???HHHHH--HHHTTT?EEE????????TT------------S????HHHHHHHHHHHT?GGG?SEEEE?SSSSSHHHHHHHHHH-HHTTB?HHHHHHHHHHHH?S-???SHHHHHHHT?????--------------- 2Q47|A PF03165.11_MH1_seed 19 177 !Q:16,18|30,30|32,32|35,57|61,92|96,96|100,110|116,116|123,127|132,132|135,137|144,144|147,147|150,151|155,156|159,164|167,168|175,176 Q:0,15|19,29|31,31|33,34|58,60|93,95|97,99|111,115|117,122|128,131|133,134|138,143|145,146|148,149|152,154|157,158|165,166|169,174 HHHHHHHHHHHHTTST---THHHHHHHHHH?T-TS?------------------????EEE------------------------------??SSS?EEE-----------TTEEE?HHHHHH-----HHHT?TT???GGGEEE?TT?SS?-GGG??SE------EE??GGGEEE?? 3KMP|A PF03166.9_MH2_seed 11 232 !Q:1,3|18,18|20,21|28,29|35,35|38,46|48,49|52,53|57,59|62,65|75,75|78,78|84,85|89,91|96,97|101,101|106,106|115,117|120,122|126,126|129,130|136,136|157,188|195,195|206,207|212,212|214,215|228,228 Q:0,0|4,17|19,19|22,27|30,34|36,37|47,47|50,51|54,56|60,61|66,74|76,77|79,83|86,88|92,95|98,100|102,105|107,114|118,119|123,125|127,128|131,135|137,156|189,194|196,205|208,211|213,213|216,227|229,231 S???SEEEEEEEESSSSB?S??EEEETT-?SEEEE?SS?----????T--TB??GGG???SS?--?HHHHHHHTT?TT?EEEEE?-SSS?--EEEE??SSS?EEEE?HHHHHHTT-??TT???EEE?TT-?EEEEE?HHHHHHHHHHHHHHHHHHHH????????????????????????????????HHHHGG-GGEEEEEESS??STTS-S??SGGGSSSEEEEE?HHH 3DIT|A PF03167.14_UDG_seed 164 295 !Q:0,1|4,4|7,7|9,9|16,18|20,20|23,28|31,32|35,35|38,38|41,49|57,57|60,60|64,91|93,94|98,116|123,123|126,144|148,155|163,163|166,167|177,177|179,182|189,189|197,197|199,199|203,211|218,236|239,240|247,248|250,251|259,279|291,291|295,295 Q:2,3|5,6|8,8|10,15|19,19|21,22|29,30|33,34|36,37|39,40|50,56|58,59|61,63|92,92|95,97|117,122|124,125|145,147|156,162|164,165|168,176|178,178|183,188|190,196|198,198|200,202|212,217|237,238|241,246|249,249|252,258|280,290|292,294 ??EE?TT?S-EEEEES???H-HH------HH--HS?SS?SH---------HHHHHHH-HH-HTT----------------------------T??GGG-------------------SEEEES?SS??-----------------GGG?----???HHHHHHH-HH--HTHHHHHHH-H?--?SEEEEB-SHHHHHH-H-HTS???------HHHHTT------------??-----EE--ETTEEE??B??HHHHHHS???------------------STTSHHHHHHH-HHH- 3NT7|A PF03168.8_LEA_2_seed 144 152 !Q:5,6|10,10|12,17|22,24|29,30|32,36|39,42|44,44|47,48|50,50|56,59|66,69|74,83|89,89|91,99|108,118|133,133|135,136|145,145 Q:0,4|7,9|11,11|18,21|25,28|31,31|37,38|43,43|45,46|49,49|51,55|60,65|70,73|84,88|90,90|100,107|119,132|134,134|137,144|146,151 EEEEE?-SSS-S?-???-EEEE---EEEE--S-----SS----S?EE--E-EEEEE????SSSSEE----EEEE--?-----??EEHHH-H---------HHHHHHHH-----------HHSEEEEEEEEEEE-E??TTTSSEEE-EEEEEE 1YYC|A PF03170.8_BcsB_seed 55 754 !Q:0,6|18,21|26,27|30,30|39,39|42,46|49,50|53,53|57,58|61,63|69,72|86,90|93,99|101,105|108,108|110,110|112,113|124,126|129,131|139,140|148,148|153,153|158,158|170,188|196,196|201,201|204,206|213,215|226,228|230,233|238,243|246,248|251,252|254,254|261,261|263,263|271,273|276,283|287,293|301,301|305,307|312,316|324,359|361,362|365,366|368,368|374,381|385,385|392,392|398,405|408,411|414,414|421,421|425,425|428,432|435,435|454,471|475,477|484,485|489,490|495,501|509,511|516,518|520,524|527,533|537,537|539,541|544,566|570,572|575,575|581,582|586,587|607,609|612,615|628,631|635,636|638,638|648,678|680,683|687,687|689,693|695,695|698,705|708,708|733,734|737,737|746,748 Q:7,17|22,25|28,29|31,38|40,41|47,48|51,52|54,56|59,60|64,68|73,85|91,92|100,100|106,107|109,109|111,111|114,123|127,128|132,138|141,147|149,152|154,157|159,169|189,195|197,200|202,203|207,212|216,225|229,229|234,237|244,245|249,250|253,253|255,260|262,262|264,270|274,275|284,286|294,300|302,304|308,311|317,323|360,360|363,364|367,367|369,373|382,384|386,391|393,397|406,407|412,413|415,420|422,424|426,427|433,434|436,453|472,474|478,483|486,488|491,494|502,508|512,515|519,519|525,526|534,536|538,538|542,543|567,569|573,574|576,580|583,585|588,606|610,611|616,627|632,634|637,637|639,647|679,679|684,686|688,688|694,694|696,697|706,707|709,732|735,736|738,745|749,753 ???-???EEEEEEEESSS??-?SSEE??TT?SEEEEEEE?SS?---?TT??BB?EEE-?SS???BTTBE----EEEEETTEEEEEE?????SS----???B?????SS-S?S--SEEEEEEEEE???SS?-?SHHHHHT??EEEEGGG?EEEE?TTSS?SSHHHHHHHHH-------------------HHHHTSS?EEEE?SS???HHHHHH---HHHHHHSSST---T????EEEE?-----TT???SS??S?EEEEEE?S?SSEEEEE---EE--------TTE-------EEEEEEE?TTS???HHHH-----HHHHSSS???---------------------------??????B??SS??B?STTTT-----???EEE?SSEEEE-EEEEE?------?SS????SS?EEEEEE?EEE?SS-?--?TT?EEEEEETTEEEEEEESSS----------------??BSS???EEEEEE--GGG??SSEE-------EEEEEEE???SSSS---S?????SS?-----?EEE?S???EE???------------------??SEE???HH-HHHTT??GGG--EEESSGGGHHHHHHHHHHS???TT????EEEEEETGGGSS????SSS??S-SHHHHHHSS?---???????-------????-????????S--??TTS?S-----S?SS????---?TT?HHHHHHHHHHHHHHHHHHHTHHHH??SS?THHHHHTT???SEEEE 4HG6|B PF03171.15_2OG-FeII_Oxy_seed 138 181 !Q:0,0|9,26|28,28|35,37|39,40|42,60|69,77|81,83|91,111|116,119|122,124|130,130|142,145|149,151|153,167|170,171|180,180 Q:1,8|27,27|29,34|38,38|41,41|61,68|78,80|84,90|112,115|120,121|125,129|131,141|146,148|152,152|168,169|172,179 ?EEEEEEEE????--------------S?GGGTTT???B??S-------------------SSEEEEEE---------SSS???EEEEETT---------------------EEEE????SS--?EEEEE?HHHHHHTTTSS????EEE???S---------------SS??EEEEEEEE? 2G1M|A PF03173.8_CHB_HEX_seed 6 191 !Q:2,2|18,19|25,31|35,35|45,46|49,49|51,56|62,62|65,65|79,79|89,89|92,94|96,96|99,99|110,112|118,121|124,126|128,128|132,133|136,136|141,147|150,159|165,171|176,176|181,187 Q:0,1|3,17|20,24|32,34|36,44|47,48|50,50|57,61|63,64|66,78|80,88|90,91|95,95|97,98|100,109|113,117|122,123|127,127|129,131|134,135|137,140|148,149|160,164|172,175|177,180|188,190 TT?EEEEEEEETTGGGGT??TTTTT------?GGG?EEEEEEEEE??SS?B???-??EEEEE?SS?EEEESSTTEEEEE?STTEEEEEE?TT???B?TT?EEEEEEEEES???SGGGS????EE---E?TTS??EE?GGGS-------SS---------?GGGTB????---TTTT?SSTT???????HHH 1QBA|A PF03174.8_CHB_HEX_C_seed 264 139 !Q:1,8|10,10|15,17|23,27|30,31|37,41|49,49|54,68|71,91|93,94|96,96|98,99|101,102|104,117|123,125|128,128|131,131|133,135|138,138 Q:0,0|9,9|11,14|18,22|28,29|32,36|42,48|50,53|69,70|92,92|95,95|97,97|100,100|103,103|118,122|126,127|129,130|132,132|136,137 T????????E-EEEE---TTEEE-----EE?-SSTTS-----EEEEESS-SSSS-------------?-EE?------------------?-T--T-S??B??S-?-----------?EEEEE--?TT-SS?B???EE? 1QBA|A PF03175.8_DNA_pol_B_2_seed 35 614 !Q:2,9|17,17|34,52|55,55|58,62|74,75|82,82|95,111|119,131|134,134|136,136|146,149|152,154|156,156|159,162|165,168|185,187|197,198|204,204|213,215|228,294|302,302|306,310|314,314|319,319|324,325|327,333|350,350|362,362|364,367|371,371|377,380|388,388|391,399|402,402|404,404|407,415|418,418|421,421|425,425|444,448|465,465|472,474|484,485|491,498|506,506|514,515|518,521|528,528|533,533|539,542|544,546|548,548|566,567|591,592|600,600|602,602 Q:0,1|10,16|18,33|53,54|56,57|63,73|76,81|83,94|112,118|132,133|135,135|137,145|150,151|155,155|157,158|163,164|169,184|188,196|199,203|205,212|216,227|295,301|303,305|311,313|315,318|320,323|326,326|334,349|351,361|363,363|368,370|372,376|381,387|389,390|400,401|403,403|405,406|416,417|419,420|422,424|426,443|449,464|466,471|475,483|486,490|499,505|507,513|516,517|522,527|529,532|534,538|543,543|547,547|549,565|568,590|593,599|601,601|603,613 HH?-------SEEEETT-HHHHHHHHHHHHHHTT------------------?EE?SS---??TTEEEEEEBTT??EEEEEE-EEEESSSSEEEE-----------------EEEEGGG-------------TS?S?HHHHHHHTT????SS???T-TS-???TT????HHHHHHHHHHHHHHHH---HHHHHHHTT??SSSHH-HHHHHHHH---HHHHHHHHHHHS?---------------------------------------------------------------???HHHHHHH-HHT?????EEE?GGGB-SSEE??E-------EEEEETTHHHHHHHHS?EEEEEEEEEES-S????TTS?EEEEE----EEEEEEE?TT??----???EE?S?SS??-----??EE?SB?TTS?EEEEEEHHHHHHHHHHEE-----EEEEEEEEEEEEEEES?SSHHHH---HHHHHHHHT??HHHHH--------HHHHHHH-HHHHHHS??SB--??BEEEEE?TTSS-EEEEE????B???S?HHHHHHHHHHHHHHHHH--HHHHTTTTEEEEESSEEEEESSS??GGGGGGB?S-SSTTSEEEEEE 1XI1|A PF03176.10_MMPL_seed 34 436 !Q:6,13|17,17|20,21|24,27|30,44|52,52|56,57|61,62|71,92|95,113|118,119|121,125|137,138|144,147|150,151|168,170|172,172|175,175|178,180|217,218|240,240|243,246|250,253|257,257|260,260|278,281|287,289|293,296|326,327|331,331|337,337|358,358|365,369|371,414|421,432 Q:0,5|14,16|18,19|22,23|28,29|45,51|53,55|58,60|63,70|93,94|114,117|120,120|126,136|139,143|148,149|152,167|171,171|173,174|176,177|181,216|219,239|241,242|247,249|254,256|258,259|261,277|282,286|290,292|297,325|328,330|332,336|338,357|359,364|370,370|415,420|433,435 HHHTTS???--???EES?SS??TT????EE?????-------???SHHHHHT?EEE??SSS??EEHHHHEE----------------------EE-------------------EEES??S----?EEEETTEEEEE--EEEEE?---SS??THHHHHHHHHHHHTTS---T?SS?EE---EEEEESHHHHHHHHHHHHHHHHHHHHHHHHTTTTTS??HHHHTTTTTHHHHHHHTTTTT-TS----STT????SSS-SS-THHHHHHHHHHHHHHHH----HHHHH???SSS----SGGGTSSSSSHHHHHHHHHHHHHSGGGGS??SSS?TTSSS-SSSHHHHHHHHHHHHHHHSS-SHHHHS-----S??????????--------------------------????????STHHHH------------TTT 1OY6|A PF03177.9_Nucleoporin_C_seed 63 894 !Q:0,5|27,34|37,95|114,116|128,157|162,165|168,169|171,173|180,180|199,207|233,302|311,339|351,351|380,381|408,408|411,411|424,425|433,469|475,475|486,486|489,489|499,515|526,561|574,575|590,591|593,593|595,611|629,631|633,634|637,654|675,676|685,744|749,752|765,765|768,779|793,805|821,822|824,869|878,893 Q:6,26|35,36|96,113|117,127|158,161|166,167|170,170|174,179|181,198|208,232|303,310|340,350|352,379|382,407|409,410|412,423|426,432|470,474|476,485|487,488|490,498|516,525|562,573|576,589|592,592|594,594|612,628|632,632|635,636|655,674|677,684|745,748|753,764|766,767|780,792|806,820|823,823|870,877 ??????SHHHHHHHHHTTSSSHHHHTT????????SS-------------------------------------------------??????????HHHHHHHHHHHHTTTTTS???TTHHHHHHHHH------------------------------HTTS????SS??S???HHHHTT?GGGTSSTTTTSSSSSSSS?????-???TTSSHHHHHHHHHHHTTHHHHTTTT-??????---????-???--?????------------------------------??????-????????TTHHHHHH-----------------------------HHHTTTTTTSS?HHHHHHTTTHHHHHHHHHHHHHHHHHTT??SSSGGGTTHHHHHHHTTTTTSTTHHH-HS?TTTHHHHHHHTS??HHHHHHH-------------------------------------HHHSS?TTHHHHHHHS?SS?HHHHTHHHH?????????????-???GGGTHHHHHT-----------------------------------?SSSHHHHHHHTT-?HHHHHHHHHHHHHH??S?H-----------------HHHHHHHHHHHHHHHHS???H--HH------------------HHHHHHHHHHHHHHHHHHHT??TTHHHHTT??----------------------------------------------------------SSSS????HHHHHHHSSSTT?TT??----------HHHHHTTTTTTSS-????????----HHHHHHHHHHHHHHT--T---???????-----------------------------???????HHHHHHHH???????????????? 3CQG|B PF03178.10_CPSF_A_seed 80 533 !Q:11,27|30,35|37,38|42,46|48,48|59,60|62,84|86,93|102,103|106,106|109,109|111,122|127,127|135,153|163,163|166,169|177,178|182,182|189,189|198,198|202,206|214,216|218,221|228,234|236,242|245,248|257,257|259,259|264,266|271,278|283,283|290,291|293,295|297,297|304,305|308,308|310,310|327,331|334,336|342,367|377,377|380,380|387,420|432,432|435,436|441,443|462,476|479,481|486,490|495,495|497,500|502,502|505,511|523,529 Q:0,10|28,29|36,36|39,41|47,47|49,58|61,61|85,85|94,101|104,105|107,108|110,110|123,126|128,134|154,162|164,165|170,176|179,181|183,188|190,197|199,201|207,213|217,217|222,227|235,235|243,244|249,256|258,258|260,263|267,270|279,282|284,289|292,292|296,296|298,303|306,307|309,309|311,326|332,333|337,341|368,376|378,379|381,386|421,431|433,434|437,440|444,461|477,478|482,485|491,494|496,496|501,501|503,504|512,522|530,532 EEEEEEEETTT------??---------EE------E--EEE?--?-T-TEEEEEEEEE??T-----------------------T????----EEEEEEEE??SS?SS?S-----------?EEEE-EEEESSS------------------?EEEEEEEEE-SS?---EEEEEEE--TTE-EEEEET-TEEEEEEE?TTS----?EEEEEEE???S---?EEEEEE-------E-------TT----EEEEEESS-B?EEEE---EEET--------TTTE-EEEEEE??S--?B?EEEEEE?-SS-S-EEEEEETTSEEEEEEE---?-SS???HHHHT--------------------------BEEEEEEEE?SS?EEEEEE???????????????-------------------EEEEEEEETTS?EE--EEEE-??HHHHHHHHHHHHHHHHHS?-------------?TT???HHHH-----TSEE?S----S?EE?-----?BSEEEHHHHHG-------GGG 3I8E|A PF03179.10_V-ATPase_G_seed 34 107 !Q:0,1|59,71|104,106 Q:2,58|72,103 ??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH????--???????TTSSSHHHHHHHHHHHHHTHHHHHHHHHHHHS??? 4EFA|G PF03180.9_Lipoprotein_9_seed 35 270 !Q:5,5|15,16|27,27|35,35|68,69|72,74|83,85|89,97|100,100|106,109|112,112|139,139|142,144|147,148|155,156|159,160|164,165|168,168|178,179|187,187|192,192|197,198|203,203|207,209|211,211|213,214|217,218|224,224|226,228|245,245|257,259|261,261|268,269 Q:0,4|6,14|17,26|28,34|36,67|70,71|75,82|86,88|98,99|101,105|110,111|113,138|140,141|145,146|149,154|157,158|161,163|166,167|169,177|180,186|188,191|193,196|199,202|204,206|210,210|212,212|215,216|219,223|225,225|229,244|246,256|260,260|262,267 EEEEE?TTTHHHHHH--HHHHHHHTTT-EEEEEEE?SSSSHHHHHHHTTSSSEEEEEEHHHHHHHHHH--HT???EEEEEEEE???EEE?--------SS?SSGGG?--?TT?EEEEESSHHHHHHHHHHHHHTTSSEE?TT-??TT??GGGEEE?-TT??EEE--EE?GGGHHHHGG--GSSEEEE?HHHH-HHTT??HHHH?SEE?-?S-S--SS??EEEEE?T---TTTTSHHHHHHHHHTT-SHHHHHHHHHH---H-TTSSEE?? 3TQW|A PF03190.10_Thioredox_DsbH_seed 98 211 !Q:0,1|6,8|20,21|23,23|37,38|45,45|48,48|61,61|72,72|82,82|98,98|100,108|116,116|118,118|121,121|129,134|137,142|145,147|150,174|189,189|191,191|203,206 Q:2,5|9,19|22,22|24,36|39,44|46,47|49,60|62,71|73,81|83,97|99,99|109,115|117,117|119,120|122,128|135,136|143,144|148,149|175,188|190,190|192,202|207,210 ??GGGG???HHHHTTTTSSS??B?SSHHHHHHHHHHT??EEEEEE?TT?HHHHHHHHHTTT?HHHHHHHHHH?EEEEEETTT?HHHHHHHHHHHHHHH-S??------?SSEEEEE?T-TS?EEEEESS??----SS-----?BT---TB-----------------??------HHHHHHHHHHHHHH-S-HHHHHHHHHHT---?SHHH 2LST|A PF03192.8_DUF257_seed 28 250 !Q:5,5|9,9|12,12|15,17|22,22|24,24|27,27|36,36|39,41|43,46|49,49|64,71|79,81|85,86|96,97|99,101|109,114|119,120|131,136|138,138|140,141|148,148|154,154|157,157|159,159|174,174|177,177|181,182|197,197|200,200|213,214|221,223|225,228|234,234|242,242|245,245|248,249 Q:0,4|6,8|10,11|13,14|18,21|23,23|25,26|28,35|37,38|42,42|47,48|50,63|72,78|82,84|87,95|98,98|102,108|115,118|121,130|137,137|139,139|142,147|149,153|155,156|158,158|160,173|175,176|178,180|183,196|198,199|201,212|215,220|224,224|229,233|235,241|243,244|246,247 SHHHH-TTS?TT?EE---EEEE?T-TS?THHHHHHH-HH---H?---SS?BEEEEETTHHHHHH--------HHHHHTT???HHH--HTSEEEEES-?S???SEEEEEE----??BTTB??HHHHHHHHTT??----S?S--EEEEEE?HHHHH-HH-S?HHHHHHHHHHHHHH-TT?TTE--EEEEEEEHHHHHHH?HH-HHHHHHHHSSEE--EEEETT---E----EEEEE?SSTTTTT?EE?TT?? 2EKD|A PF03193.11_DUF258_seed 74 222 !Q:12,14|18,19|22,23|28,28|38,38|59,127|132,136|145,145|147,147|150,152|155,157|173,176|179,179|184,185|187,189|192,192|194,195|197,197|209,209 Q:0,11|15,17|20,21|24,27|29,37|39,58|128,131|137,144|146,146|148,149|153,154|158,172|177,178|180,183|186,186|190,191|193,193|196,196|198,208|210,221 HHHHHHHHHHHT??-EEE??HH--HHTT?TTTGGGGTT-SEEEEEESHHHHHHHHHHHH??---??----------------------------------------??????????????????????EEEE-----TTEEEESS?S?SS???TT-??HHHHGGGSHHHHHHG----GG?SSTT??S---SS?S--S?HHHHHHHHTSS?HHHHHHHHHHHH 4A2I|V PF03198.9_Glyco_hydro_72_seed 12 367 !Q:0,5|9,10|24,32|34,35|41,56|59,59|62,63|67,67|70,71|85,85|92,94|98,99|111,111|118,118|121,122|126,127|131,136|153,153|167,167|171,171|174,175|197,200|206,208|224,245|247,247|253,257|260,262|278,278|281,281|288,294|298,304|306,308|323,324|330,330|333,334|338,339|344,344|348,348|352,352|365,366 Q:6,8|11,23|33,33|36,40|57,58|60,61|64,66|68,69|72,84|86,91|95,97|100,110|112,117|119,120|123,125|128,130|137,152|154,166|168,170|172,173|176,196|201,205|209,223|246,246|248,252|258,259|263,277|279,280|282,287|295,297|305,305|309,322|325,329|331,332|335,337|340,343|345,347|349,351|353,364 ??????TTS??EEEETTEEEETTT-------??B??EEEEE????????????????SS?SS??GGG?HH--HHHHHHHHHHHHT?SEEEES???TTS??HHHHHHHHHTT?EEEEES?BT--TBS??TTS?--???HHHHHHHHHHHHHHTT?TTEEEEEEEESSS?STT?GG--GHHHHHHHHHHHHHHHHHSSS????EEEEE???TTTHHHHHHHTTBTT?-------------------??S?EEEEE????-SS-??HHHHSHHHHHHHHTT?SS?EEEEEE???----SSS-------S???THHHHHTSHHHHTT??EEEES?SB??SSS??SEEE?TTS?EEE?HHHHHHHHHHHH?? 2W62|A PF03199.10_GSH_synthase_seed 51 145 !Q:2,2|9,9|12,12|30,34|39,39|50,65|68,69|71,76|78,82|87,88|99,99|105,107|110,116|119,120|138,138|145,145 Q:0,1|3,8|10,11|13,29|35,38|40,49|66,67|70,70|77,77|83,86|89,98|100,104|108,109|117,118|121,137|139,144 TT?EEEEEE?SS?TTHHHHHHHHHHHHHHH-?-??EEEE?HHHHHHHEEE?---------------TT--S-----?E-----EETT--EEEEEEEEES?SSGGG?--SS-------HH--HHHHHHHHHHSSSEEET?HHHHHH- 3KAL|A PF03200.11_Glyco_hydro_63_seed 15 1064 !Q:0,39|44,51|66,67|76,76|79,81|90,90|92,93|102,102|104,104|106,109|113,115|149,149|151,155|159,159|174,182|193,194|197,206|208,208|211,212|216,231|238,238|260,268|270,272|277,279|283,283|289,291|294,294|302,324|339,347|352,353|359,361|363,366|368,372|378,383|402,402|405,422|445,448|450,451|453,464|466,467|469,469|486,486|496,497|500,515|518,519|521,525|527,527|535,544|548,549|556,556|574,574|589,589|592,596|600,601|610,610|617,617|620,624|642,671|676,676|703,703|705,707|714,716|720,720|722,723|726,727|730,738|743,743|747,749|752,753|756,756|758,758|781,781|788,792|804,805|819,819|824,824|827,896|900,900|905,908|920,920|922,923|926,926|938,938|952,952|960,960|963,968|973,973|975,975|990,992|998,998|1001,1003|1030,1031|1035,1035|1038,1038|1040,1041|1048,1048|1059,1062 Q:40,43|52,65|68,75|77,78|82,89|91,91|94,101|103,103|105,105|110,112|116,148|150,150|156,158|160,173|183,192|195,196|207,207|209,210|213,215|232,237|239,259|269,269|273,276|280,282|284,288|292,293|295,301|325,338|348,351|354,358|362,362|367,367|373,377|384,401|403,404|423,444|449,449|452,452|465,465|468,468|470,485|487,495|498,499|516,517|520,520|526,526|528,534|545,547|550,555|557,573|575,588|590,591|597,599|602,609|611,616|618,619|625,641|672,675|677,702|704,704|708,713|717,719|721,721|724,725|728,729|739,742|744,746|750,751|754,755|757,757|759,780|782,787|793,803|806,818|820,823|825,826|897,899|901,904|909,919|921,921|924,925|927,937|939,951|953,959|961,962|969,972|974,974|976,989|993,997|999,1000|1004,1029|1032,1034|1036,1037|1039,1039|1042,1047|1049,1058|1063,1063 ------?---------------------------------HHHH--------HHHHHHHHHHSSSB??TTBSSEEB?TT???EEEEEEEE?T--TSTTGGGG?B?B--??GGG-??SEEEEEEEETTTEEEEEEEETTTTEEEEEEEEE?T-----TSS?EEEEEEEEESSTTS?-?------EEEEEEEEEE??HH----------H-HS??EEE----------------EEEESS?EEEEEEETTTEEEEEEEEEEE?-------?B???TTSS???TTS?EEEEE???GG-GGGGHHH-----------------------HHHHHHHHHHHHHT?????????GGGH--HHHTS???T----T?????SEEEE------EEEEETTEEEEEEEEETT?SS???--------------?HHHHHHHHHHHHHHHHHHHHHH????S-?S------------S??S?HHHHHHHHHHHHHHHT?EEEEEEEEE??SS?-------------??TT??S?????S?EEEEEEE----------EEE??SBTTTB?SEEHHHHHHHHHHHHHH?HHHHHHHHHHHHTT?TT?????SEE??HHHHHTTS?GGGTEE?TT?????HHHHHHHHHHHHHHHHH-------???????????????????????HHHH?HHHHHHHHHHHHHHHHHHHHHHHHHT-B???STGGGS--?TTS?B??TT??SS-------??GGGS?TTS???SS??TT?B?HHHHHHHHHHHHHHHHHHHHTT?HHHHHH-----HHHHHHHHHHH--HHHTTEETTTTEE?EEEE?TT----------------------------------------------------------------------TSS?EEEE-???BHHHHHHHHTT?S?-TT?THHHHHHHHHH?TTTTEETTEEBSB?TTSTTTT?TT?-----SSSS?B?HHHHHHHHHHHHHH?--GGGGS?SS???HHHHHHHHHHHHHHHHHHHHHHHTSS??SEE?TT-T??EESSSS?TTGGGGHHHH----H 2Z07|A PF03201.11_HMD_seed 13 100 !Q:33,35|58,58|67,67|79,79|85,86 Q:0,32|36,57|59,66|68,78|80,84|87,99 HHHHHHHHSTTHHHHHHHHHHHHHHHHHHHHTS???HHHHHHHHHHHHHHHHHHHHHH?GGGGGGTS?GGGGGGTGGGG?SGGGT--THHHHHHHHHHHT 3F47|A PF03205.9_MobB_seed 28 175 !Q:0,0|8,8|28,29|35,51|57,57|62,62|68,68|72,74|81,82|88,88|99,100|102,102|110,110|113,113|115,117|119,121|125,125|135,135|138,138|144,144|147,154|158,158|161,161|164,164 Q:1,7|9,27|30,34|52,56|58,61|63,67|69,71|75,80|83,87|89,98|101,101|103,109|111,112|114,114|118,118|122,124|126,134|136,137|139,143|145,146|155,157|159,160|162,163|165,174 ?EEEEEES?HHHHHHHHHHHHHHHHHTT??EEEEE????-??????????--HHHHH-HHHT?EEEEE?SSE---EEEEEE??HHHHT?HHHHHHHHTT--T?SEEEEES?GG-G???E---EEE?SSGGGGGGG?SS?EEEEE?SS?------?SSS?EE?TT?HHHHHHHHHH 1YR8|A PF03211.8_Pectate_lyase_seed 12 236 !Q:2,4|8,27|39,39|42,42|45,49|52,52|54,57|64,64|72,72|75,76|79,79|86,88|100,100|103,103|108,108|117,117|122,122|125,125|130,131|137,138|162,162|165,165|168,171|197,197|202,202|209,209|215,216|222,223|228,230 Q:0,1|5,7|28,38|40,41|43,44|50,51|53,53|58,63|65,71|73,74|77,78|80,85|89,99|101,102|104,107|109,116|118,121|123,124|126,129|132,136|139,161|163,164|166,167|172,196|198,201|203,208|210,214|217,221|224,227|231,235 EE???EES??????????--????-???TTEEEESSEEE?TT?EE?????TT?S????SEEEES?EEEEEEE?TT??TT?EEEEES---EEEEEEEEESS?SS?SEEE?SSEEEEES?EEEE?TT?TTSS??EEEEE??SSEEEEEETTEEEEEEEEEEEEE?SS?TT????EEEEESSEEEEEEEEEEEEEEGGGT?EEEE?SEEETT?BTTBS??EEEEE??BTTB???EEEEE 4EW9|A PF03212.9_Pertactin_seed 8 142 !Q:9,9|14,23|26,26|29,31|34,34|42,43|53,58|63,63|71,71|84,86|89,92|98,99|102,102|109,109|114,114|117,117|123,123|127,132|140,141 Q:0,8|10,13|24,25|27,28|32,33|35,41|44,52|59,62|64,70|72,83|87,88|93,97|100,101|103,108|110,113|115,116|118,122|124,126|133,139 EEEEEEETT?EEEE-------???SS-TT???EE-EEEEEEE??EEEEEEETT------TTEE?EEEEEEE?EEEEEEEEEEEE???SS???-EEEEE??TT?EEEEEE?SGGG?EE?SSEEE?EEE?-----SSSEEEE?? 1DAB|A PF03220.8_Tombus_P19_seed 4 173 !Q:0,8|19,20|22,24|26,27|32,37|47,55|75,76|78,78|90,90|102,103|106,107|148,148|150,172 Q:9,18|21,21|25,25|28,31|38,46|56,74|77,77|79,89|91,101|104,105|108,147|149,149 ?????????HHHHHHHHTT??S???S??SBSS??????HHHHHHHTT?????????SEEEEEEEETTEEEEEEEE??S?HHHHHHHGGGB?HHHHHHHHHTT??SS??EEEEEEEETTEEEEEEEEGGGHHHHHHHHHHHHHHHHTSS?S??????????????????-???? 1RPU|A PF03221.11_HTH_Tnp_Tc5_seed 194 87 !Q:15,17|22,25|36,36|39,51|56,56|59,62|65,69|79,86 Q:0,14|18,21|26,35|37,38|52,55|57,58|63,64|70,78 THHHHHHHHHHHHHH---GGGT????HHHHHHHHHH-HH-------------HHHT?TT????HH-----HHHHHHHHT-------? 1HLV|A PF03222.8_Trp_Tyr_perm_seed 13 448 !Q:0,1|3,3|50,56|64,66|68,68|80,80|82,83|107,109|120,124|132,133|151,151|179,180|186,193|227,227|229,229|260,260|272,273|291,291|317,318|321,322|324,325|328,329|331,331|342,375|388,393|396,396|406,407|423,430|436,436 Q:2,2|4,49|57,63|67,67|69,79|81,81|84,106|110,119|125,131|134,150|152,178|181,185|194,226|228,228|230,259|261,271|274,290|292,316|319,320|323,323|326,327|330,330|332,341|376,387|394,395|397,405|408,422|431,435|437,447 ??B?HHHHHHHHHHHHHHHHTTTSHHHHHHHHGHHHHHHHHHHHHHHHHH-------HHHHHTT???T-TTHHHHHHHHH?S--SHHHHHHHHHHHHHHHHHHHHHH---HHHHHHHHTT-????HHHHHHH--HHHHHHHHHHHHHHTHH-HHHHHHHHHHHHHHHHHHHHHHHHHHH??GGGTS?-----??SHHHHHHHHHHHHHGGGGGHHHHHHTTGGGBSS-H-HHHHHHHHHHHHHHHHHHHHHHHHHHHTTS?HHHHHHTGGGH--HHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHTTHHHHHHHS??SS??T--TS??S?THHHHHHHHH----------------------------------HHHHHHHSHHHH------HH-HHHHHHHHH--HHHHHHHHHHTHHHH-----???HHHHH-HHHHHHHHHHH 3GIA|A PF03223.10_V-ATPase_C_seed 33 1013 !Q:9,11|15,16|19,20|28,28|40,46|48,48|50,67|100,102|106,106|110,111|113,114|119,567|575,585|590,590|594,594|601,603|639,666|668,668|673,674|678,679|681,685|689,691|693,693|696,697|724,753|755,755|758,759|764,768|770,770|782,805|820,820|822,822|826,831|854,897|932,932|935,936|945,945|947,949|951,951|953,953|969,973|976,1009 Q:0,8|12,14|17,18|21,27|29,39|47,47|49,49|68,99|103,105|107,109|112,112|115,118|568,574|586,589|591,593|595,600|604,638|667,667|669,672|675,677|680,680|686,688|692,692|694,695|698,723|754,754|756,757|760,763|769,769|771,781|806,819|821,821|823,825|832,853|898,931|933,934|937,944|946,946|950,950|952,952|954,968|974,975|1010,1012 EEEEEEETT???TTS--TT??HHHHHHH-TGGGGTSEEEE????-??B?S?-----------------GGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHT---TSS?SSS??S??BTTB----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?HHHHHHT----???---?TTTS?TTS-BHHHHH---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT---------------------------?S?TTTS??TTT??G-----GGS??-S?SS--EEEEEEEEEGGGHHHHHHHGGGSSTT------------------------------B?TT??EEEE-----E?SSEEEEEEEEE------------------------GGGHHHHHHHHHHT-T?EEE-?????HHHHHHHHHHHHHHHHHHHHHH--------------------------------------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?SS??EEEEEEEE?T---T?H-HHHHHHHHHHHGGGG?----TT???????????????????------?????????SSE 4EFA|C PF03224.9_V-ATPase_H_N_seed 37 604 !Q:13,19|30,30|46,70|85,87|101,101|105,105|108,109|121,123|134,134|136,141|143,143|151,153|168,169|175,189|194,196|203,204|207,210|213,213|215,294|298,325|359,359|366,448|491,494|511,513|522,558|569,569|573,573|582,587 Q:0,12|20,29|31,45|71,84|88,100|102,104|106,107|110,120|124,133|135,135|142,142|144,150|154,167|170,174|190,193|197,202|205,206|211,212|214,214|295,297|326,358|360,365|449,490|495,510|514,521|559,568|570,572|574,581|588,603 HHHHHHHHHHHHS----???HHHHHHTTSS?HHHHHHHHHHHHHHH??-???--???-?????-???????SSTTHHHHHHHHHS???HHHHHHHHHHHHH-HHH?SS--SSHHHHHHHHH--?TTHHHHHHHH?S?-----S-SHHHHHH---HHHHHHHHHTSTTT??HHHHH---------------HHHH--?HHHHHH--HH?---TT?H--------------------------------------------------------------------------------HHH----------------------------HHHHHHHHHHHTSHHHHHHHHTTHHHHHHHHHH-HHHHHH???------------------------------------------------------------------??????????-???HHHHHHHHHHHHHHHTTSHHHHHHHHTTSHHHHHHHHHHHHH??--SHHHHHHHHHHHHHTT---SSSSTTHH-------------------------------------HHHHHHHHHH?HHH-HHHHHHSS??----SSHHHHHHHHHHHHHH 1HO8|A PF03230.8_Antirestrict_seed 27 110 !Q:1,9|19,19|23,23|26,34|42,42|50,50|67,69|74,79|94,95|109,109 Q:0,0|10,18|20,22|24,25|35,41|43,49|51,66|70,73|80,93|96,108 H??-??????EEEEEETTS?EEE-EE?????????EEEEETT-TTEEEEE?HHHHHHHHHHHHHHHH---HHHH?----?HHHHHHHHHHHHHH--HHSTTHHHHHHHT? 2KMG|A PF03237.10_Terminase_6_seed 41 657 !Q:4,4|8,8|27,49|55,55|68,77|87,87|89,89|93,94|97,101|104,104|111,121|125,125|132,141|148,153|155,156|167,167|186,187|190,196|201,203|219,250|253,253|257,268|271,271|280,294|296,296|302,302|307,307|310,329|337,337|341,342|349,351|354,366|368,368|373,373|380,388|397,400|403,404|407,430|435,436|439,448|453,453|460,473|475,475|492,492|506,508|513,514|522,526|540,541|543,543|546,546|551,556|561,562|564,573|588,590|597,599|619,619|622,624|645,656 Q:0,3|5,7|9,26|50,54|56,67|78,86|88,88|90,92|95,96|102,103|105,110|122,124|126,131|142,147|154,154|157,166|168,185|188,189|197,200|204,218|251,252|254,256|269,270|272,279|295,295|297,301|303,306|308,309|330,336|338,340|343,348|352,353|367,367|369,372|374,379|389,396|401,402|405,406|431,434|437,438|449,452|454,459|474,474|476,491|493,505|509,512|515,521|527,539|542,542|544,545|547,550|557,560|563,563|574,587|591,596|600,618|620,621|625,644 EEEE?SSS?HHHHHHHHHHHHHHTSSS----------------------?EEEEE-ESSHHHHHHHHH----------HHHHHHTTS?T-TTS??EE-----EE?SSEEEE-----------TTS?EEEEEE?--------?HHHHHH------S??SEEEEETGGG?TTHHHHHHHHHHHHSSSS??EE-------EEEE???TTSHHHHHHHHHHTT?-------------------------------SS?EEE------------EE?GGGSGGGG---------------B?TTSBB?TTHH-HH--------------------HHHHTTS?HHH--HHHHHS???TT-------------S?SBSS?HHHHTT?????????SSSEEESS?-??TT??EE------------------------EEEE??SS----------BTTB?EEEEEE--------------E?SSSSEEEEEEEEESSS?TTTHHHHHHHHHH---HTTS??EEEEESH-----HHHHHHHHHHTTS??S?EE?SSSS?-----SSEE??H----------HHHHHHHHHHHHHH---HTTSEE???HHHHHHHTSEEEETTEEEE?TT???HHHHHHHHHHHHHHSGGGTT????------?? 2O0H|A PF03241.8_HpaB_seed 87 224 !Q:10,10|45,46|77,77|80,82|86,86|89,90|122,127|130,130|134,134|136,143|154,155|157,157|160,160|192,193|199,199|207,210 Q:0,9|11,44|47,76|78,79|83,85|87,88|91,121|128,129|131,133|135,135|144,153|156,156|158,159|161,191|194,198|200,206|211,223 HHHHHHHHHH-THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTG--GGSHHHHHHHHHHHHHHHHHHHHHHHHHHT?EE?--TTS?EE??HHHHHHHHHHHHHHHHHHHHHHHHHHGGGGT?--???HH-HHH-S--------TTHHHHHHHT??S-SS?HHHHHHHHHHHHHHHTSHHHHHHHHHHHHTT??HHHHH-HHHHHHS?--?HHHHHHHHHHTHH 2YYM|A PF03243.10_MerB_seed 22 144 !Q:4,5|13,14|32,32|37,37|44,44|48,49|56,56|58,58|60,63|70,70|73,73|78,81|84,85|87,90|98,98|100,101|105,105|116,116|119,119|122,122|132,132 Q:0,3|6,12|15,31|33,36|38,43|45,47|50,55|57,57|59,59|64,69|71,72|74,77|82,83|86,86|91,97|99,99|102,104|106,115|117,118|120,121|123,131|133,143 EESS??SEEEEET--TEEEEESSHHHHHHHHH-HHTS?EEEEEE?TTT??EEEEEE?S-S?---EEEEES-TT?EEEE????SS--S---?HHHHTGG-G??EES?HHHHHHHHTT?TT?TT?EEEEHHHHH-HHHHHHHHHHH 3F2H|A PF03244.9_PSI_PsaH_seed 6 146 !Q:0,56|58,61|64,64|69,70|73,73|75,79|81,82|90,90|95,95|98,98|116,117|120,146 Q:57,57|62,63|65,68|71,72|74,74|80,80|83,89|91,94|96,97|99,115|118,119 ????????-????????????????????????-???????????????????????S????SS?TTSS??SS?S?????S??SSSSSSS?TTSS?TT?STTTTTTGGGTTTTTTS??SS??-???????????????----????- 2WSE|H PF03246.8_Pneumo_ncap_seed 4 395 !Q:0,1|5,8|20,20|22,25|28,29|31,31|35,36|56,57|74,74|89,90|94,95|112,114|117,118|122,122|146,146|148,149|156,156|177,177|200,200|203,204|219,219|238,240|258,258|272,272|309,309|316,316|320,320|336,337|340,344|346,346|363,367|372,374|376,395 Q:2,4|9,19|21,21|26,27|30,30|32,34|37,55|58,73|75,88|91,93|96,111|115,116|119,121|123,145|147,147|150,155|157,176|178,199|201,202|205,218|220,237|241,257|259,271|273,308|310,315|317,319|321,335|338,339|345,345|347,362|368,371|375,375 ??TTS????HHHHHHHHHHT?S????EE??S?EEE??GGGHHHHHHHHHHHHHSTT??TTSHHHHHHHHHHHHH?HHHHHHHHHHHTEE??EEE??EEEEEEEETTEEEEEE---EE??SSS?HHHHHHHHHHHHHHHHHHHHHHS-S??TTTSTT?THHHHHHHHHHHHHHHTGGG?SSTTHHHHHHHHHHTTHHHHHH?TT??HHHHHHHHHHHHHH?HHHHHHHHHHHHHHTTSS???HHHHHHHHHHHTTTTTT?HHHHHHHHHHHTT?GGGGSHHHHHHHHHHHHHHHHHHHHGGGGGGTTTTT?GGGGGG?STT?HHHHHHHHHHHHHTT??SS?????S?HHHHHHHHHHHHHHTT?????TTSS???S???????????????????- 2YHQ|A PF03253.9_UT_seed 26 334 !Q:3,7|20,22|36,40|42,42|65,66|93,93|96,96|103,107|122,122|132,134|147,148|153,153|156,156|160,160|162,176|178,182|186,187|190,191|207,209|224,224|243,243|248,249|275,277|307,309|324,326|328,328|332,332 Q:0,2|8,19|23,35|41,41|43,64|67,92|94,95|97,102|108,121|123,131|135,146|149,152|154,155|157,159|161,161|177,177|183,185|188,189|192,206|210,223|225,242|244,247|250,274|278,306|310,323|327,327|329,331|333,333 HHH-----HHHHHHHHGGGT???HHHHHHHHHHHHH-----H?HHHHHHHHHHHHHHHHHHHHTT??HHHHHHTTTTHHHHHHHHHHHHTBTT?TT?GGGHHH-----HHHHHHHHHHHHHH-HHHHHGGGT???TTHHHHHHHHHH--HHHH?TT?SSS?B???--------????S?????GGG??HH--HHHHHHHHHHHGGGT???HHHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHH-HHTT??HHHHHTTTTTHHHHHHHHHHTTTSB???HHHHHHHHHHHHHHHHHHHHHHHHHHTTT???TTHHHHHHHHHHHH???S?TTS?B 3M6E|A PF03255.9_ACCA_seed 15 149 !Q:0,2|17,35|55,56|66,66|69,71|80,80|86,89|93,95|116,118|131,133 Q:3,16|36,54|57,65|67,68|72,79|81,85|90,92|96,115|119,130|134,148 ???STTHHHHHTTTTTT???????????-???????GGGGTHHHHHTTTTHHHHT??HHHHHHHHT?TT???HHHHHHHH?EEEEE????SSS???TTEEEEEEEETTEEEEEEEE???SSTTHHHHTGGG???HHHHHHHHHHHHHHH 2F9Y|A PF03256.11_APC10_seed 7 223 !Q:0,1|5,11|21,28|32,32|42,43|51,51|57,57|60,61|64,65|83,83|113,113|121,121|124,126|134,134|136,155|159,160|179,179|182,182|185,185|193,222 Q:2,4|12,20|29,31|33,41|44,50|52,56|58,59|62,63|66,82|84,112|114,120|122,123|127,133|135,135|156,158|161,178|180,181|183,184|186,192 ??TTS????-??HHHHHHTTS--------EEE?GGGEEEEES??BTTBSTH-HHHSS?TT??EE??SSSSEEEEEEEEEEEEE?EEEEEEEHHHHGGGSEEEEEEEEESSTTS?EEEEEEE?SS--?EEEEEEE?B-------------------?TTS--SBEEEEEEEEEEEEEGGG?SS?EE?EEEEEEE???---????????---------------- 1JHJ|A PF03259.12_Robl_LC7_seed 41 101 !Q:11,11|25,25|30,33|37,37|54,70|76,76|79,79|89,91|96,96 Q:0,10|12,24|26,29|34,36|38,53|71,75|77,78|80,88|92,95|97,100 HHHHHHHHHHH?TTEEEEEEEETTS?EEEE---?TTS?HHHHHHHHHHHHHHHH??????????--?????EEEEE?SS?EEEEEESST---TEEE-EEEE 3L7H|A PF03260.8_Lipoprotein_11_seed 6 259 !Q:0,13|18,23|39,39|55,55|71,71|86,86|95,95|105,106|121,121|124,125|129,129|138,138|145,145|173,175|177,179|183,183|191,193|198,198|220,221|226,226|229,230|234,234|243,244|247,247|252,252|258,258 Q:14,17|24,38|40,54|56,70|72,85|87,94|96,104|107,120|122,123|126,128|130,137|139,144|146,172|176,176|180,182|184,190|194,197|199,219|222,225|227,228|231,233|235,242|245,246|248,251|253,257 -------------?GGGS-----?HHHHHHHHHHHHHTT?HHHHHHHHHHHHHTT?HHHHHHHHHHHHHTT?THHHHHHHHHHHTT?HHHHHHHS?HHHHHHHHT??EEEEETTTTEEEEE?SS??STT?EEEEEESS?SSSGGG?EEEEEEEETTEEEEEEEETTTTEEEEE?--S???TTS?EEEEEES???SGGG?EEEEEEEETTEEEEEEEETTT??EEEE?SS??TTS?EEEEEESS??TT?HHHH?EEEEE? 4EFR|A PF03261.10_CDK5_activator_seed 5 415 !Q:0,260|277,277|280,280|283,284|305,305|308,308|310,311|327,327|329,329|331,336|356,356|360,362|367,368|371,371|396,396|411,414 Q:261,276|278,279|281,282|285,304|306,307|309,309|312,326|328,328|330,330|337,355|357,359|363,366|369,370|372,395|397,410 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------??---------------------------?????????----???????????---------------????????????????-?????????SHHHHHHHHHHHHHHH?TT?TT??THHHHHHHHHHHHHHHHTTS?SS?S??HHHHHHHHHHHHHHS?T-T---???HHHHHHHHHHHHHHHHHHH?SSS???SGGG??SS?HHHHHHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHTT???? 1UNG|D PF03263.8_Cucumo_2B_seed 7 113 !Q:0,2|33,35|46,70|83,112 Q:3,32|36,45|71,82 ???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHT???HHHHHHHHHH-------------------------HHHHHHHHHHHS---------?????------------???? 2ZI0|A PF03264.9_Cytochrom_NNT_seed 111 234 !Q:0,13|15,17|45,45|51,51|56,56|67,73|76,77|84,84|86,87|91,91|110,113|116,118|120,130|140,142|152,152|157,159|162,199|204,205|214,218|220,220|223,229|231,231 Q:14,14|18,44|46,50|52,55|57,66|74,75|78,83|85,85|88,90|92,109|114,115|119,119|131,139|143,151|153,156|160,161|200,203|206,213|219,219|221,222|230,230|232,233 ??---??----???S---TTTHHHHHHHHHHHHHHHHHTTSHHHH-TTSGG-GHHH-HHHHHHSTTT-------TS?-THHHHS?S--SHH-HHHHHHHHHHHHHHHHHH----TS???S??------???HHHHHHHHH---HHHHHHHHH-HTTS--?TT--------------------------------------TSSS--SGGGTSGG-----G-TT-------T-TT 2J7A|C PF03266.10_NTPase_1_seed 38 223 !Q:0,0|6,7|10,10|26,26|28,30|35,36|40,41|55,55|58,58|65,73|77,78|80,81|89,89|93,95|105,111|114,118|122,124|131,131|144,144|147,151|156,161|164,165|175,179|185,190|194,210|213,215 Q:1,5|8,9|11,25|27,27|31,34|37,39|42,54|56,57|59,64|74,76|79,79|82,88|90,92|96,104|112,113|119,121|125,130|132,143|145,146|152,155|162,163|166,174|180,184|191,193|211,212|216,222 ?EEEES??SS?HHHHHHHHHHHHHHT-T???EEEE??EEE--TTSSEEEEEEEET-TS?EEEEEE??--??-??SSS??E--ESSSSEE?HHH---HHTTTTTTT???????SS?-???EEE???STTTTT?SHHHHHHHHHHH?SS??---EEEE?????-SS??TTHHHHHTT??---SEEEE----??SSS-----------------GG---GHHHHHH 1YE8|A PF03270.8_DUF269_seed 41 126 !Q:4,4|14,15|22,25|28,29|53,55|61,62|64,64|68,68|86,88|92,93|118,118|122,122|125,125 Q:0,3|5,13|16,21|26,27|30,52|56,60|63,63|65,67|69,85|89,91|94,117|119,121|123,124 TTTS?HHHHHGGGB??HHHHHH????SS??HHHHHHHHHHHHHHHHHHHHHHS???EEEEE--E?SSS?EEEEEEETTEEEEEEEE?-?GGG??BSSHHHHHHHHHHHHHHHHHHHHH?HHH-HT? 3G7P|A PF03271.12_EB1_seed 61 77 !Q:24,35|42,61 Q:0,23|36,41|62,76 HHHHHHHHHHHHHHHHHHHHHHHH------------HHHHTT--??????????????????HHHHHHHHHHHHHHH 1WU9|A PF03273.8_Baculo_gp64_seed 6 523 !Q:0,3|7,21|37,37|57,57|61,61|64,64|74,76|88,88|92,94|109,109|112,113|118,122|124,124|126,128|132,134|161,161|165,166|173,173|177,177|179,182|186,186|189,190|200,200|202,204|216,223|226,228|231,231|235,236|240,248|254,254|258,259|261,261|263,263|273,276|278,299|303,307|354,354|365,365|375,375|381,388|391,391|394,394|397,397|402,409|411,414|417,443|447,447|470,522 Q:4,6|22,36|38,56|58,60|62,63|65,73|77,87|89,91|95,108|110,111|114,117|123,123|125,125|129,131|135,160|162,164|167,172|174,176|178,178|183,185|187,188|191,199|201,201|205,215|224,225|229,230|232,234|237,239|249,253|255,257|260,260|262,262|264,272|277,277|300,302|308,353|355,364|366,374|376,380|389,390|392,393|395,396|398,401|410,410|415,416|444,446|448,469 ????GGG???????????????SEEEEEEEEEEEEEE?SEEEEEEEEEEEEEEEEEE?TTT?TT?EEEEEEEEE???HHHHHHHHHHT?EEE???EEEEEGGGGGHHHH?SS??SEEE-----S?B???EEE???SBTEEEEEEEEEEEEEEEEEEEEEEE?TTT??EEEEEB?TTS?B????SSS?EE--ETTEEEEES-S???EEEEEEEEEEE--------EE???SS?TTS??EEE---------EESSS?EEE??S?S?EEETTEEEE----E??????????????????????TTS--???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?TTHHHHHTTS?EEEEESSSS?EEEEE????????SS?SS?SS?STTT????????S????SS???????--??????????????????GGG?HHHHHHHHHHHHHHHHTTSEEE?????????????????????????????????????????----------?? 3DUZ|A PF03275.8_GLF_seed 96 269 !Q:13,13|15,15|19,19|21,23|27,30|32,32|36,38|40,43|48,48|50,51|54,54|62,63|66,68|71,75|80,80|82,85|92,104|116,116|118,118|127,129|131,134|142,152|157,157|161,161|171,173|178,178|189,200|202,202|213,219|223,229|232,233|251,251|253,255|260,260|268,268 Q:0,12|14,14|16,18|20,20|24,26|31,31|33,35|39,39|44,47|49,49|52,53|55,61|64,65|69,70|76,79|81,81|86,91|105,115|117,117|119,126|130,130|135,141|153,156|158,160|162,170|174,177|179,188|201,201|203,212|220,222|230,231|234,250|252,252|256,259|261,267 HHTHHHHHHHHSS?G-GGS?T---TSS????B?SSS???S?-??SEEE?B--TT?HHHHHHH--HH---TT-----SEEE?S?--?GGGSHH-------------HHHTTEEEEEE?S?HHHHTTTT---T????EEEEEEE-----------EEEE-SSS?SSSSSEEEE??-TTSS?SEEEEGGGGS??-----?---?S?EEEEEEEEEE?-----?TTS----???EE??SHHHHHHHHHHHHHHHH?T---TEEE?STTTTTS? 3KYB|A PF03276.9_Gag_spuma_seed 7 670 !Q:0,8|12,12|25,30|33,33|41,41|48,48|59,59|61,61|64,64|74,74|76,76|78,80|83,83|85,86|92,92|103,106|118,121|124,124|130,134|141,142|175,179|184,500|502,564|567,669 Q:9,11|13,24|31,32|34,40|42,47|49,58|60,60|62,63|65,73|75,75|77,77|81,82|84,84|87,91|93,102|107,117|122,123|125,129|135,140|143,174|180,183|501,501|565,566 ?????????EEB?HHHHHHHHHHTT??????TT?EEEEEES?BTTBSS?EEEEEEEEEE?T-TS?EEEEEEEEE?S-S???TT?S--SEEEE?HHHHTTTBTT????SGGGGGGGGTT????TT?HHHHH?????HHHHTT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----HHHH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------H---------------------------------------------------------------HT----------------------------------------------------------------?-------------------------------------- 4JNH|A PF03278.8_IpaB_EvcA_seed 9 160 !Q:0,9|28,30|59,62|78,78|80,83|86,89|95,98|102,102|116,118|142,142|144,144|147,147 Q:10,27|31,58|63,77|79,79|84,85|90,94|99,101|103,115|119,141|143,143|145,146|148,159 ??????????HHHHHHHHHHHHHTSSSS???HHHHHHHHHHHHHHHHHHHHHHHHHHHT????HHHHHHHHHHHHHHH-T????TT????HHHHH----HHT?HHHHHHHHHHHTT???HHHHHHHHHHHHHHHHHHHHHHH?T-TS?HHHHHHHHHHHH 3LXR|F PF03280.9_Lipase_chap_seed 34 214 !Q:13,33|35,38|40,40|60,60|85,93|105,106|113,113|135,137|146,146|151,151|184,185|188,190|206,207 Q:0,12|34,34|39,39|41,59|61,84|94,104|107,112|114,134|138,145|147,150|152,183|186,187|191,205|208,213 HHHHHHHHHHHTT?????-----------?????S????H-HHHHHHHHHHHHHHHHHTG-GGHHHHHHHHHHHHHHHHHHHHHH?????????HHHHHHHHTTS??HHHHHH-HHHHHHHHHHHHHHHHHHHTT-??HHHHHHHH-HTTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--TT???HHHHHHHHHHHHHHH??STTHHH 2ES4|D PF03281.9_Mab-21_seed 33 499 !Q:2,4|6,6|9,9|16,24|30,31|35,54|61,61|70,97|99,99|102,103|110,134|140,140|150,150|157,187|191,192|195,205|209,211|215,215|217,217|226,235|247,247|249,251|257,273|288,289|291,291|297,334|337,338|341,342|344,345|350,350|361,362|374,375|393,395|407,408|423,425|427,427|431,431|433,433|452,455|459,460|462,462|465,465|467,471|473,473|477,477|482,482 Q:0,1|5,5|7,8|10,15|25,29|32,34|55,60|62,69|98,98|100,101|104,109|135,139|141,149|151,156|188,190|193,194|206,208|212,214|216,216|218,225|236,246|248,248|252,256|274,287|290,290|292,296|335,336|339,340|343,343|346,349|351,360|363,373|376,392|396,406|409,422|426,426|428,430|432,432|434,451|456,458|461,461|463,464|466,466|472,472|474,476|478,481|483,498 TT???S?SS?TTEEEE---------EEEEE??SEE--------------------EEESTT?SSEEEEEE---------------------------?S?SS??GGGGGE-------------------------ETTEE?HHHHHHHHH-HHHHHH-------------------------------HHT??SS?----------EEE???GGG?S?EEEEETTT----------EEEEEEEEEEE?S???GGGSS????-------------HHHHHHHHHHHHTT--S?EEEEE?------------------------------------?SS??SS??S??EEEE?HHHHHHHHHT??SSTTTTTSGGG??SHHHHHHHHHHHHHHHH---HHTTTTTSSSS??HHHHHHHHHHHHHH???G-GGG?G-GGHHHHHHHHHHHHHHHH----HTT??B?SS?T-----T?BTT?TTTS?HHHHHHHHHHHHHHHH 4K99|A PF03284.8_PHZA_PHZB_seed 8 165 !Q:5,8|10,10|17,18|32,33|55,55|60,60|83,83|110,111|115,116|142,142|152,159|162,164 Q:0,4|9,9|11,16|19,31|34,54|56,59|61,82|84,109|112,114|117,141|143,151|160,161 GGGTT???-S?SSSHHH--HHHHHHHHHHHHT??GGGGGGGGGGEEEEEEEEESS?SSSS?EEEESHHHHHHHHHHHHHHSTT?EEEEEEEEEBSSTTEEEEEEEEEEEE??TTS??EEEEEEEEEEEEEETTEEEEEEEEE?HHHHHHHTT????????TT??? 3JUM|A PF03288.11_Pox_D5_seed 41 131 !Q:0,3|15,15|19,19|21,21|23,25|28,30|32,33|36,36|52,52|54,63|74,74|81,89|95,111|121,121|130,130 Q:4,14|16,18|20,20|22,22|26,27|31,31|34,35|37,51|53,53|64,73|75,80|90,94|112,120|122,129 -???HHHHHGGGEEE?SSS?S?B???TT-??S??TT-TBHHHHHHHHHHHTT?S?------???HHHHHHHHHH-HHHHTT??-----??EEEET-----------------TEEEESEEE?THHHHHTS? 1KA8|A PF03291.11_Pox_MCEL_seed 11 571 !Q:0,58|61,233|256,263|270,270|284,284|293,293|305,307|313,323|330,331|336,336|345,349|351,352|354,355|363,363|397,397|402,406|413,416|424,424|427,427|435,441|443,445|448,449|454,462|466,468|510,546|551,551|560,560|570,570 Q:59,60|234,255|264,269|271,283|285,292|294,304|308,312|324,329|332,335|337,344|350,350|353,353|356,362|364,396|398,401|407,412|417,423|425,426|428,434|442,442|446,447|450,453|463,465|469,509|547,550|552,559|561,569 -----------------------------------------------?------?????HH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHHHHHHHHHHHHHHHHHHHHT???--???EEEEET?TTTTTHHHHHHTT?SEEEEEES?HHHHHHHHHHH---HHHHH???????---?EEEEEE??TTTS?GGGTSSST-----T??E--EEEEEET?GGGGGGSHHHHHHHHHHHHTTEEEEEEEEEEEE?HHHH-----HHHHHH----SSSSEEE?SS?EEEESSS-------S???SS??EEEE??????-??EEE???HHHHHHHHGGGTEEEEEEEEHHHHHHHHTTSHHHHHHHHHH?????????????????????????????????????SSSS?HHHHHHHT-TEEEEEEEE? 2VDW|A PF03296.8_Pox_polyA_pol_seed 13 163 !Q:0,2|10,12|19,20|22,37|40,43|58,62|78,78|81,83|86,86|92,92|111,111|117,117|132,132|140,141|149,149|160,160 Q:3,9|13,18|21,21|38,39|44,57|63,77|79,80|84,85|87,91|93,110|112,116|118,131|133,139|142,148|150,159|161,162 ???TTHHHHH---HHHHHH??S???????--???????TT----HHHHHHHHHHHHHH----?TTTEEEESHHHHHTT?SS???SS?EEEES?HHHHHHHHHHHHHHHSSS?EEEEE?TTSSSEEEEEETTS?EEEEEEE??HHHHHHS?EEEETTEEEE?HH 2GAF|D PF03297.10_Ribosomal_S25_seed 24 116 !Q:0,48|50,52|66,66|69,69|80,81|98,100|102,105|108,115 Q:49,49|53,65|67,68|70,79|82,97|101,101|106,107 ?????????-????????????????????-??????????????????S??-HHHHHHHHHHSTT?SS?SHHHHHHSSS??SSHHHHHHHHHTTSSS???S-???SS???????? 2XZM|8 PF03301.8_Trp_dioxygenase_seed 5 354 !Q:0,15|29,32|39,41|76,78|82,82|111,111|123,123|129,130|142,143|148,148|152,152|154,154|159,161|165,165|176,177|189,189|192,193|198,200|223,223|234,234|249,249|262,263|265,265|317,317|319,320|324,324|341,341|343,343|353,353 Q:16,28|33,38|42,75|79,81|83,110|112,122|124,128|131,141|144,147|149,151|153,153|155,158|162,164|166,175|178,188|190,191|194,197|201,222|224,233|235,248|250,261|264,264|266,316|318,318|321,323|325,340|342,342|344,352 -----------??-??SHHHHTTHHHHTT????HHHHTT???TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSS???HHH-HHHHHHHHHHHHHHHHHHHHHHHHHTTS?HHHHHTTGGGS?TTGGG??HHHHHHHHHHT??GGGS?STT?S-HHHH???HHH-HHHHHHHHHS??HHHHHHHHHHT?TT??TTTT?--HHHHHHHHHHHHHHHHHHHHHT?SSHHHHHHHH-HHHHHHHHHHHHHH?HHHHHHHHHTTS??S?HHHHHHHHHHHHSTTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?S??TTS?SSHHHHHHHHTTSTTS?S?HHHHTGGGG? 1YW0|A PF03306.8_AAL_decarboxy_seed 71 238 !Q:5,5|13,17|27,27|33,34|38,38|52,52|56,60|64,66|69,70|79,82|84,84|93,93|107,109|130,135|138,140|148,149|167,167|172,172|176,176|190,190|200,200|211,212|217,220|225,228|231,232|236,237 Q:0,4|6,12|18,26|28,32|35,37|39,51|53,55|61,63|67,68|71,78|83,83|85,92|94,106|110,129|136,137|141,147|150,166|168,171|173,175|177,189|191,199|201,210|213,216|221,224|229,230|233,235 EEEES?HHHHHTT?????EEHHHHGGG?SEEEE??GGG?SEEEEETTEEEEE?TTS---?-EEE??-TT?-EESSEEEE????S-EEEEEEEE?SHHHHHHHHHHHH?-?TTSEEEEEEEEEEEEEEEEE???-??SS???HHHHHTT-?EEEEEEEEEEEEEEEEE?GGGT-TTS?BEEEEEEEETTSS?EEEEEEEEE-EEEEEEEEEE??EEEE??-?SHHH----HH??GGG?? 1XV2|A PF03308.11_ArgK_seed 9 303 !Q:9,10|29,31|39,40|61,62|69,86|91,96|98,98|105,111|131,132|139,139|141,141|152,152|165,165|170,171|178,178|185,187|211,231|233,236|238,241|300,300 Q:0,8|11,28|32,38|41,60|63,68|87,90|97,97|99,104|112,130|133,138|140,140|142,151|153,164|166,169|172,177|179,184|188,210|232,232|237,237|242,299|301,302 HHHHHHHHH??SHHHHHHHHHHHHHHGGG???SEEEEEE??TTSSHHHHHHHHHHHHHTTT??EEEEEE??????????????????HHHH------T?TTEEEE???????HHHHHHHHHHHHHHHHHTT??EEEEEE?S?SSHHHHHHTT?SEEEEEEESSTT?TTTT??TTSGGG?SEEEEE???GGGHHHHHHHHHHHHHHHHHHST---------------------T--??S????EEEEBGGGTBSHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHT?HH 3TK1|A PF03309.9_Pan_kinase_seed 194 313 !Q:6,6|19,28|33,36|41,42|44,45|48,59|76,77|79,88|91,93|101,101|116,118|120,129|132,139|141,141|144,149|152,152|154,154|156,159|161,162|166,166|179,179|182,185|187,187|189,190|197,197|207,209|213,213|215,216|225,225|235,266|268,270|273,276|296,296|300,302|305,311 Q:0,5|7,18|29,32|37,40|43,43|46,47|60,75|78,78|89,90|94,100|102,115|119,119|130,131|140,140|142,143|150,151|153,153|155,155|160,160|163,165|167,178|180,181|186,186|188,188|191,196|198,206|210,212|214,214|217,224|226,234|267,267|271,272|277,295|297,299|303,304|312,312 EEEEEE?SSEEEEEEEETT----------EEEE----EEEE--E??TT??----------HHHHHHHHHHHHHHTT??G----------GG??-EEEEEES?HHHHHHHHHHHHHH---T?------???EE-------?S-TT???-??EE?S-S---?G--GGS?HHHHHHHHHHHH-HH?---S-S--EEEEEE-SSEEEEEEE?--TTS-E--EEEEEEEE?HHHHHHHHH???????--???---------------????-S--?SS---?SSHHHHHHHHHHHHHHHHH-HHH---HH-------H 3BF3|A PF03310.8_Cauli_DNA-bind_seed 3 126 !Q:32,33|56,56|68,125 Q:0,31|34,55|57,67 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS??HHHHHHHHHHHHHHHHHHHHHT?TTHHHHHHHHT???--???????????--?????????????????????????????????-?????? 3F6N|A PF03315.10_SDH_beta_seed 190 260 !Q:0,15|32,32|35,63|67,68|71,74|76,77|84,86|93,93|109,110|115,115|118,130|148,150|152,162|165,169|174,175|178,178|184,184|187,190|192,195|197,197|199,200|207,216|219,221|225,225|241,246|249,250|252,254|258,259 Q:16,31|33,34|64,66|69,70|75,75|78,83|87,92|94,108|111,114|116,117|131,147|151,151|163,164|170,173|176,177|179,183|185,186|191,191|196,196|198,198|201,206|217,218|222,224|226,240|247,248|251,251|255,257 ???-????-???????TTTHHHHHHHHHHHHH-HH-----------------------------HTT-?TT----T??EEEEEE--?HHHHHS?TTSSHHHHHHHHHTT??TTSS?GG-------------GHHHHHHHHHHHTEEEE---T-----------TT-----EEEE??HH-HHEEE?TT???-S----S?S--SEEEEE----------EE?--TTS?EEEEEEEEEETTTEE------EE--T---TTS?? 2IQQ|A PF03318.8_ETX_MTX2_seed 15 286 !Q:9,9|12,12|20,24|30,31|43,44|62,62|66,66|71,73|89,89|91,95|99,100|106,106|108,115|119,121|123,124|127,128|132,134|137,138|151,153|158,158|176,176|187,187|192,208|211,213|216,218|221,224|234,234|239,244|248,248|250,250|260,260|277,278|285,285 Q:0,8|10,11|13,19|25,29|32,42|45,61|63,65|67,70|74,88|90,90|96,98|101,105|107,107|116,118|122,122|125,126|129,131|135,136|139,150|154,157|159,175|177,186|188,191|209,210|214,215|219,220|225,233|235,238|245,247|249,249|251,259|261,276|279,284 HHHHHHHHH?TT?GGGTTTS---??EEEEE??EEEEEEEEESS??EEEEEEEEEEEEEEEEE?SSS?EEEE???EEEEEEEEEEEEEEE?S?----SSS??EEEEE?S?------?SSS???E--EE--EES---SS??EEEEEEEEEEEE???EEEE?TTEEEEEEEEEEEEEEE-EEEEEEEEEE?EEEE-----------------EE???TT???EE----EEEESGGGT?TTTS-----?TTS?E-EEEEEEEEE-EEEEEEEEEEEEETTT??EEEEEE? 1W3A|A PF03319.8_EutN_CcmL_seed 51 103 !Q:0,0|4,7|15,15|19,19|25,25|34,44|47,48|61,63|66,66|73,73|84,84|86,86|88,93|101,101 Q:1,3|8,14|16,18|20,24|26,33|45,46|49,60|64,65|67,72|74,83|85,85|87,87|94,100|102,102 ?EEE----EEEEEEE?SSB?GGGTT?EEEEEEEE?----------TT??EEEEEEEEEESS???TT?EEEEEE-HHHHHHHHSS-T-T???---SEEEEEE?S 2RCF|A PF03320.8_FBPase_glpX_seed 111 379 !Q:0,0|4,6|29,29|50,50|56,59|63,69|71,71|73,73|76,76|80,83|85,87|89,89|91,102|112,121|123,123|134,134|136,139|141,142|150,150|152,159|164,168|172,172|186,188|192,192|198,202|214,214|221,222|235,238|240,240|264,264|272,306|308,309|311,311|320,321|323,323|333,334|338,340|343,347|352,352|360,360|369,369|376,377 Q:1,3|7,28|30,49|51,55|60,62|70,70|72,72|74,75|77,79|84,84|88,88|90,90|103,111|122,122|124,133|135,135|140,140|143,149|151,151|160,163|169,171|173,185|189,191|193,197|203,213|215,220|223,234|239,239|241,263|265,271|307,307|310,310|312,319|322,322|324,332|335,337|341,342|348,351|353,359|361,368|370,375|378,378 ?GGG---HHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHTTSS?EEEEE----ESS???????S-S?TT?EES-?--S--?S?E------------EEEEEEEEE??????????S?EEEEEEEETT?B????S?-EEEEEEE?G--------GGTT???--TTS?HHHHHHHHHHHTT-??GGG?EEEEE?????HHHHHHHHHTT?EEEEES??HHHHHHHHHSTT-?--S?SEEEEEEEHHHHHHHHHHHHHTT?EEEEEEE????????????????????-??????--??---?T--T?EEEHHHHB??S?EEEEEEESS??SSS???EE-----ETTE-EEEEEEE-EETTTTEE-EEEEEE--E 2R8T|A PF03321.8_GH3_seed 64 742 !Q:4,9|11,12|18,37|42,44|56,56|69,70|72,77|79,82|84,91|93,100|108,116|118,118|123,123|134,143|148,148|151,154|173,173|191,192|198,199|201,201|206,207|211,217|220,220|222,222|225,225|229,229|237,238|242,243|247,254|257,258|262,262|268,268|270,270|322,324|327,329|332,338|347,350|365,370|381,382|388,388|406,408|411,412|416,416|419,420|425,425|427,427|431,431|435,436|440,440|444,445|455,474|478,480|484,487|493,494|497,497|505,505|509,529|540,540|558,559|561,561|565,566|568,568|581,582|589,593|602,602|605,605|608,609|614,614|626,632|634,651|654,656|662,663|674,677|688,689|691,693|699,699|702,702|704,724|727,735|738,740 Q:0,3|10,10|13,17|38,41|45,55|57,68|71,71|78,78|83,83|92,92|101,107|117,117|119,122|124,133|144,147|149,150|155,172|174,190|193,197|200,200|202,205|208,210|218,219|221,221|223,224|226,228|230,236|239,241|244,246|255,256|259,261|263,267|269,269|271,321|325,326|330,331|339,346|351,364|371,380|383,387|389,405|409,410|413,415|417,418|421,424|426,426|428,430|432,434|437,439|441,443|446,454|475,477|481,483|488,492|495,496|498,504|506,508|530,539|541,557|560,560|562,564|567,567|569,580|583,588|594,601|603,604|606,607|610,613|615,625|633,633|652,653|657,661|664,673|678,687|690,690|694,698|700,701|703,703|725,726|736,737|741,741 HHHH------H--HHHHH--------------------HTHH---HHHHHHHHHHH-HHSTTSHHHHTT??T------T?--?S--------H--------HHHHHHS?-------?B?HHHH-HHHHHHHHTT?--------?SSSS?SS?-??EEEEEEEEETTEEEEEEE?TTHHHHHHHHHHHHHHH--HHHHS??G-GGSE--EEE???????EE?T-TS?EEE?HHHHHHT--SHH--HHT???----?TT??BSS?HHHHH?S?HHHHHHHHHHHHHHTGGGEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHT???TT???HH-------HHHHTTTT????HHHHHHHHHHHTSS?----?TTTHHHHSTT??EEEEE?SGGGGGGHHHHHHHHTS-??EE??EEE?SS-?EEEE?S?TTS?GGG??EEE?TTS?-EEEEEEGGG--------------------TTS???SSS????EEGGG??TT?EEEEEEE?TTS-------------------??SEEEEEEEEE-EEEETTEEEEEEEEETT??B?SSS??B?HHHHHHHHHHHH--HGGGGT-----TEEEEEEE-EE-EE-?SSSS?EEEEEEEEEES------?G------------------GG???HHHHH--HHHHHHHHHS---?HHHHHHHHTS??S???EEEEE?TT?S??????????-??????????SS?--?????-HH---H 4EQL|A PF03325.8_Herpes_PAP_seed 6 329 !Q:13,15|17,17|21,23|26,26|33,33|45,62|83,83|98,99|121,121|123,123|130,130|134,134|142,142|153,328 Q:0,12|16,16|18,20|24,25|27,32|34,44|63,82|84,97|100,120|122,122|124,129|131,133|135,141|143,152 EEETTEEEEEEEE???S?EEE???SS?SEEEEE?HHHHHHHHHHH??????????????????EEEEEEETTTTEEEEEETTS?EEEEESBTTEEEEE??SEEEEEEHHHHHHHHHHHHTT?S?EEEEEE?SSS?EEEEEEE?SSEEEEEEEE?????????-??????????--------------------------------------------------------?----------------------------------------------------------------??--------------------------------- 1YYP|A PF03328.9_HpcH_HpaI_seed 22 267 !Q:6,6|8,9|20,21|32,45|61,61|68,68|71,72|79,84|90,91|97,99|113,113|117,125|127,127|150,150|157,157|170,171|175,182|184,185|190,190|200,200|203,203|215,215|226,226|231,235|237,237|251,252 Q:0,5|7,7|10,19|22,31|46,60|62,67|69,70|73,78|85,89|92,96|100,112|114,116|126,126|128,149|151,156|158,169|172,174|183,183|186,189|191,199|201,202|204,214|216,225|227,230|236,236|238,250|253,266 EEEEEE?S??HHHHHHHHTT??SEEEEETTTS?-----------??HHHHHHHHHHHTTSS-SEEEEE?SS??HHHHHH------HHHTT??EEEES???SHHHHHHHHHHHS?TTT????-----S?GGGSGGGGGGTSTTHHHHHHHH?EEEEEE?SHHHHHTHHHHH--TST--------T??EEEE?HHHHHHHTT?TT?TTSHHHHHHHH-HHHHHHHHTT?EEEE-----E?SSHHHHHHHHHTT??EEEEEEHHHHHHHH 1A3X|A PF03330.13_DPBB_1_seed 127 140 !Q:0,0|8,14|20,20|23,23|27,27|29,30|34,34|38,38|42,56|59,59|65,65|70,72|81,99|108,108|117,117|119,127|130,130|132,133|136,136 Q:1,7|15,19|21,22|24,26|28,28|31,33|35,37|39,41|57,58|60,64|66,69|73,80|100,107|109,116|118,118|128,129|131,131|134,135|137,139 ?EEEEEEE?-----?GGGTT-SB?TTS?B??TTS?EEE?SSS--------------?TT?EEEEE-ETTT-??EEEEEEEE????---------------STTEEEEE?HHHHHHHT?T---------TT-S?-EE-EEE 4FER|A PF03331.8_LpxC_seed 10 289 !Q:0,0|2,3|10,10|17,17|21,21|30,32|35,36|42,42|47,48|53,54|58,59|62,63|67,67|71,71|74,75|79,80|92,93|104,106|122,122|127,128|132,133|138,138|140,140|154,155|164,168|172,172|182,185|196,198|213,213|217,218|222,222|226,226|228,228|232,232|236,237|261,261|271,272|286,286 Q:1,1|4,9|11,16|18,20|22,29|33,34|37,41|43,46|49,52|55,57|60,61|64,66|68,70|72,73|76,78|81,91|94,103|107,121|123,126|129,131|134,137|139,139|141,153|156,163|169,171|173,181|186,195|199,212|214,216|219,221|223,225|227,227|229,231|233,235|238,260|262,270|273,285|287,288 ?E--EEEESS?EEEEEE?TTT?SEEEEEEE???TT??EEEEE?SSSS-?EEEE??GGG--EE??SSS?EEE?TT??EEE??HHHHHHHHHHT??SEEEEESSSB???TTSSSHHHHHHHHHH?EEEE--EEE??EEEE?S?EEEEETTEEEEEE??SSEEEEEE?????TTS?GGGSEEEEE--??HHHHHHHTTT???EEEHHHHHHHHHTT?STT??TTT?EEE?S-SSB?STT??SSTTHHHHHHHHHHHHHHGGGSS?EEEEEEEES??HHHHHHHHHHHHH?TT 2JT2|A PF03332.8_PMM_seed 9 228 !Q:6,6|18,18|21,21|30,34|41,41|61,63|69,69|87,89|91,93|95,95|106,107|110,110|112,114|129,129|144,145|154,154|158,158|166,166|179,181|189,189|191,198|211,211|222,222|226,227 Q:0,5|7,17|19,20|22,29|35,40|42,60|64,68|70,86|90,90|94,94|96,105|108,109|111,111|115,128|130,143|146,153|155,157|159,165|167,178|182,188|190,190|199,210|212,221|223,225 HHHHHH-HHHTTSEEEEE?SS?HHHHHHHH----?TTHHHH?SEEESGGGTSEEETTEEEE???HHHHH?HHHHHHHHHHHHHHHTT???S???S?SSEEETTEEE??SS?S???HHHHHHHHHHHHHH?HHHHHHHHHHHHTT--TSSEEEEE?SSS?EEEEETT?SGGGGGGGTTTS?-?SEEEEEE?S????????HHHHSTTEEEEE?SSHHHHHHHH-HHH?? 3F9R|A PF03333.8_PapB_seed 14 95 !Q:0,8|20,22|25,25|27,27|39,42|56,58|68,69|95,95 Q:9,19|23,24|26,26|28,38|43,55|59,67|70,94 ??????-??HHHHHHHHHHH???TT?S?HHHHHHHHHHS????HHHHHHHHHHHTT???HHHHHHHTT??HHHHHHHHHHHHHHHHHHHHHGGGG- 3M8J|A PF03335.8_Phage_fiber_seed 38 14 !Q:0,1|3,4|6,7|13,13 Q:2,2|5,5|8,12 ??B??B??EEEEE? 2XGF|A PF03340.8_Pox_Rif_seed 11 594 !Q:0,22|24,24|27,30|32,32|34,34|39,39|46,46|50,50|52,52|56,57|61,61|66,67|70,70|83,84|94,94|109,114|135,135|144,144|151,151|155,155|159,159|163,164|172,173|179,180|185,185|188,189|192,193|201,202|210,210|214,214|219,220|224,227|240,244|251,254|259,260|263,263|266,267|271,273|286,287|289,289|293,294|298,300|303,304|328,331|333,334|337,338|341,342|346,347|350,350|356,356|367,368|371,371|383,383|389,390|419,421|427,428|437,437|440,441|443,445|452,452|455,457|460,461|467,469|471,472|491,491|503,503|506,507|511,521|523,525|527,527|532,535|538,538|545,546|554,557|581,581|585,586|591,593 Q:23,23|25,26|31,31|33,33|35,38|40,45|47,49|51,51|53,55|58,60|62,65|68,69|71,82|85,93|95,108|115,134|136,143|145,150|152,154|156,158|160,162|165,171|174,178|181,184|186,187|190,191|194,200|203,209|211,213|215,218|221,223|228,239|245,250|255,258|261,262|264,265|268,270|274,285|288,288|290,292|295,297|301,302|305,327|332,332|335,336|339,340|343,345|348,349|351,355|357,366|369,370|372,382|384,388|391,418|422,426|429,436|438,439|442,442|446,451|453,454|458,459|462,466|470,470|473,490|492,502|504,505|508,510|522,522|526,526|528,531|536,537|539,544|547,553|558,580|582,584|587,590 ????????------???---???B?SS????B?B?EEEE-EEEEEE?EEE-E?STT??EEE-EEEE??TT?SEEEEEEEEEEE??EESSEEEEE?TTHHHHTEEEEEEE------ETTEEEEEEEHHHHHHHHTT?HHHHHHTT?SHHHHS?EEE?STT?EEE??EEEEEEE??TTSTT--TTTT?EE?-TT??EEEEEEE??GGGTEEE?TTS?HHHH--HHH????EEEEEEEEEEES?????EEEEEE----EEEE??TT?SE--EEE???SEEEEEEEEEEE--E?TTS??EES???TT??SHHHHHHHHHHHHHHHHEEEESS----S??SS-?TT??EEE??TT?EEEET-TEEEEEEEES??TT?EEEEETTSBEE?SSTTS??EEGGGGEEEEEEEEETTTTEEEEEEEEE???TTGGG??HHHHTSTT?SS??B???HHHHTT?EE???TT??TTSTT??-S??EEEEEEEETTEEEEEESS?HHHHHHHHHHT?SS??EEE-----------E???S?TTTB????EE?BGGGTB??EEEEEEE????TTSGGGGSEEEEEEEEEEEEEEE?TTS-?EEEE??? 2YGB|A PF03341.8_Pox_mRNA-cap_seed 9 288 !Q:0,1|10,10|15,18|21,26|30,35|40,41|56,56|68,72|83,85|90,90|93,95|102,102|104,104|107,108|112,126|131,131|135,136|146,146|149,149|158,160|183,183|187,187|191,192|201,201|218,218|221,222|226,227|229,229|232,233|236,238|272,272|286,287 Q:2,9|11,14|19,20|27,29|36,39|42,55|57,67|73,82|86,89|91,92|96,101|103,103|105,106|109,111|127,130|132,134|137,145|147,148|150,157|161,182|184,186|188,190|193,200|202,217|219,220|223,225|228,228|230,231|234,235|239,271|273,285 ??HHHHHHHH?EEEE????SS??????EES??????TTTT??HHHHTHHHHHHHTS?HHHHHHHHGGG?????HHHHHHHHTT???EESS?TT???SEEEEE?S?TT??BSS???????????????BSSS?GGG??GGGGHHHHH?SS?SEEEEEES???SHHHHHHHHHHHHHEEEEEEEE?TTS?SSS??EEEEEEEE?HHHHHHHHHHHHHHHT?SS??GGG?-S?EE??SS???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTT?SSSSHHHHHHHTT?? 2VDW|B PF03344.10_Daxx_seed 7 869 !Q:0,232|256,256|259,259|265,265|268,268|280,307|321,327|332,337|340,340|347,366|373,373|375,375|378,382|399,402|433,433|435,446|451,451|484,868 Q:233,255|257,258|260,264|266,267|269,279|308,320|328,331|338,339|341,346|367,372|374,374|376,377|383,398|403,432|434,434|447,450|452,483 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------??HHHHHHHHHHHHHHHHHHHHHHH?EE?TGGGG?TT?HHHHHHHHHHH----------------------------HHHHHHHHHHHHT???????GGGS??????SS?HHHHHH--------------------HHHHHT?S-SS?????HHHHHHHHHHHHHHTT????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?S????????????GGGT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH???????-?????------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 4H9O|C PF03347.8_TDH_seed 2 166 !Q:0,11|29,31|46,48|51,51|100,104|115,117|130,130|133,133|154,154|163,165 Q:12,28|32,45|49,50|52,99|105,114|118,129|131,132|134,153|155,162 ????????????EEEEEEEEEEGGGGSSS???EEEEEEEESSEEEE???SS?SSEEEEEEEEESSEEEEEEEEETTEEEEEEEEEEEETTEEEEEEEEES???-?SSHHHHHHHH???GGGSSEEEEEEE?SS?EEEEEEEEETTEEEEEEEEE?TTTGGGGT??? 3A57|A PF03349.11_Toluene_X_seed 22 555 !Q:0,14|16,16|18,18|23,23|30,31|35,37|44,44|52,52|54,55|58,58|71,71|75,82|84,105|108,108|113,114|126,128|142,145|148,149|157,164|168,170|173,174|183,183|194,196|217,223|226,226|228,228|234,238|244,246|257,258|260,260|262,262|266,275|294,294|304,305|308,310|316,317|319,354|361,363|365,366|377,377|391,391|395,396|399,404|410,411|413,417|420,425|429,433|460,477|480,480|491,492|505,506|508,538 Q:15,15|17,17|19,22|24,29|32,34|38,43|45,51|53,53|56,57|59,70|72,74|83,83|106,107|109,112|115,125|129,141|146,147|150,156|165,167|171,172|175,182|184,193|197,216|224,225|227,227|229,233|239,243|247,256|259,259|261,261|263,265|276,293|295,303|306,307|311,315|318,318|355,360|364,364|367,376|378,390|392,394|397,398|405,409|412,412|418,419|426,428|434,459|478,479|481,490|493,504|507,507|539,554 -----------????S?S?SHHH-HHHTTT??SSS???GGGGGS?GGGTTSS?S--EE-EEEEEEEEEEEE-EEE????????B??--------------------TT?SSSS??EEEEEEEEEEE---ETTEEEEEEEEEE????EE??SSSBTTB?-------SSS???SS??EEEEEEEE-EEEEEEEESS---SSEEEEEEEEEEEEEEEEEE-------EE?S?SSSST-----TTSSS???TTTTTTTSSS??S?E-EEE??????????EEEEEEEEEEEEEEEEET-TEEEEEEEE??BB???EEEEE??B?????????------------------------???EEEEEE???B??EEEEEEEEES-SSSEEEEEEEEEE?GGG??SE------EEEEE??S-----SS??????EEE?????EEEEEEEEEEEEETTEEEEEEEEEEE???????-??????????EE-EEEEEEEESS--TTEEEEEEEEEE??B????????-----?----------??????-EEEEEEEEEEEEEEEE 2R89|A PF03352.8_Adenine_glyco_seed 190 219 !Q:1,6|8,13|27,32|50,50|69,69|74,76|79,86|94,94|97,97|101,103|123,124|127,133|143,144|147,148|151,155|162,167|169,172|187,188|190,191|207,210|217,218 Q:0,0|7,7|14,26|33,49|51,68|70,73|77,78|87,93|95,96|98,100|104,122|125,126|134,142|145,146|149,150|156,161|168,168|173,186|189,189|192,206|211,216 T?----?S-----?HHHHHHHHHTTTS?-??-?HHHHHHHHHHHHHTTTS?HHHHHHTHHHHHHHTGGG?HHHH---HT?-----?-HHHHHHH-TT?TTS???HHHHHHHHHHHHHHHHHHT--TT-----??HHHHHHTTS-?SS?-EE??--?SSGGGS?-----S--??HHHHHHHHHHHHTT??S??HHHHHHHHHHTTSEE-???TTSTTS?? 1P7M|A PF03357.16_Snf7_seed 34 213 !Q:31,34|41,45|47,58|99,109|117,118|143,162|177,212 Q:0,30|35,40|46,46|59,98|110,116|119,142|163,176 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH----HHHHHT-----T?-----------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH???????????HHHHHHH--HHSTTSHHHHHHHHHHHHHHHHHS?????????????-??????TTSTTTHHHHHHHT?????-------------------???????????? 2LUH|B PF03358.10_FMN_red_seed 276 275 !Q:0,0|6,6|9,18|20,26|29,35|47,52|54,59|61,69|71,72|75,89|92,99|102,114|120,127|129,131|135,139|149,149|151,152|158,159|166,166|178,178|181,201|203,203|207,207|209,209|212,226|230,231|234,234|253,253|255,256|259,259|262,263|266,266|270,270 Q:1,5|7,8|19,19|27,28|36,46|53,53|60,60|70,70|73,74|90,91|100,101|115,119|128,128|132,134|140,148|150,150|153,157|160,165|167,177|179,180|202,202|204,206|208,208|210,211|227,229|232,233|235,252|254,254|257,258|260,261|264,265|267,269|271,274 ?EEEEE-ES??--------S-------TT------?HHHHHHHHHHT------T?----?T---------T-?EE---------------EE?-?----?TT---??-----???HHHHT--------T???HHH-----HHHHHHHHH?S--EEEEE??EETTEE?HHHHHHHHHHT?SS---------------------S?TTT-T?EE---------------EEE--EE?SSTTTTHHHHHHHHHHHH-H--HT?EE??SS?EEE?SGGG 3U7R|A PF03360.11_Glyco_transf_43_seed 15 285 !Q:9,9|22,23|25,25|35,35|38,39|45,64|79,81|86,87|89,91|94,95|101,102|108,108|115,115|119,119|121,122|127,128|134,160|173,174|181,186|191,193|196,209|223,228|231,234|238,238|240,242|244,244|254,257|261,261|264,265|271,276|279,281|283,284 Q:0,8|10,21|24,24|26,34|36,37|40,44|65,78|82,85|88,88|92,93|96,100|103,107|109,114|116,118|120,120|123,126|129,133|161,172|175,180|187,190|194,195|210,222|229,230|235,237|239,239|243,243|245,253|258,260|262,263|266,270|277,278|282,282 HHHHHTTSS-SEEEEEEESSSS??H-HHHHHHHHH?SE--EEEEE????????????????????SHHHHHHHHHHHTT???EEEE??S???TT??EEEEE??TTSEE?HHHHHH-HTS?S--SEEE??EEEET---------------------------TEEEEEEEEETT--EEEEEE----??SSTT--?SS???-----------GGGEEEEHHHHHH-----?TT????TTS?T---T?HHHHHHTTT?--?GGG?EE?-HHHHT---???EE???B?? 1V84|A PF03364.15_Polyketide_cyc_seed 95 265 !Q:3,3|6,6|14,14|17,19|21,22|25,26|29,61|72,75|81,93|97,97|103,104|107,109|120,154|167,167|178,223|236,239|241,241 Q:0,2|4,5|7,13|15,16|20,20|23,24|27,28|62,71|76,80|94,96|98,102|105,106|110,119|155,166|168,177|224,235|240,240|242,264 ESS?TH-HHHHHHT-TT---T??SS??SS??----------------------------???EEEEEEETTE----EEEEE-------------EEE?STTSS??EE---EEEEEEETTT?----------------------------------EEEEEESSTTSS?EEEEEEEEEE----------------------------------------------TTEEEEEEEEEE--??S?HHHHHHHHHHHHHHHHHHHHHHH 3NJ1|A PF03366.11_YEATS_seed 63 129 !Q:0,0|8,16|18,18|22,49|60,62|68,69|71,71|75,75|78,81|92,93|102,102|105,108|110,113|120,128 Q:1,7|17,17|19,21|50,59|63,67|70,70|72,74|76,77|82,91|94,101|103,104|109,109|114,119 ?EEEEEEE---------E?GGG---------------------?-?--?-TTTEEEEEEE??-TTSSS-?E-EEE?SS----SEEEEEEESS??EEEEEEEE?GG----G????EEEEEE????????? 3FK3|A PF03367.8_zf-ZPR1_seed 14 168 !Q:2,3|7,8|11,11|15,16|20,21|25,26|34,34|38,39|47,47|51,53|62,62|69,69|74,74|77,77|89,90|95,95|116,119|123,125|129,129|143,145|151,151|161,163|166,167 Q:0,1|4,6|9,10|12,14|17,19|22,24|27,33|35,37|40,46|48,50|54,61|63,68|70,73|75,76|78,88|91,94|96,115|120,122|126,128|130,142|146,150|152,160|164,165 EE??TTT??TT?EEE--EEE??TTS??EEEEEEE?SSS??EEEEEEE?SSS???EEEEEEEE?SGGGGG?EEEE?TT?EEEEGGGTEEE?-TTTT?SEEEEHHHHHHHHHHHHHSS???-SSS???GGG?HHHHHHHHHHHHH---HTTSS?EEEEEEETT???EE?? 2QKD|A PF03368.9_Dicer_dimer_seed 29 110 !Q:14,14|17,18|21,21|28,30|34,43|47,47|51,54|57,57|60,62|67,67|91,91|93,93|98,99|101,102|106,106|108,108 Q:0,13|15,16|19,20|22,27|31,33|44,46|48,50|55,56|58,59|63,66|68,90|92,92|94,97|100,100|103,105|107,107|109,109 HHHHHHHHHTTSSS?TT??SS?EEEEEE??-GGG---------?EEE-EEE??--TT?SS??-EEEE-EESSHHHHHHHHHHHHHHHHHHH?S?TTTS??H--HHH?S?T 2KOU|A PF03370.8_CBM_21_seed 75 200 !Q:9,11|18,24|35,36|40,41|49,50|62,62|65,69|73,73|77,107|112,116|118,120|122,162|165,166|173,174|178,178|180,183|191,191|195,197 Q:0,8|12,17|25,34|37,39|42,48|51,61|63,64|70,72|74,76|108,111|117,117|121,121|163,164|167,172|175,177|179,179|184,190|192,194|198,199 HHHHSSEEE---EEEEEE-------TTEEEEEEEE??SSS??EEEEEEE--SSTTSSEEEEE?EE??--?SSS?SSS----?--------------------------EEEE?????S???T-----------------------------------------TS??EEEEEE--EET-T----EEEEESG-GGS???EE 2EEF|A PF03372.18_Exo_endo_phos_seed 326 889 !Q:1,2|5,6|8,8|10,42|50,72|74,94|98,106|112,130|132,133|137,157|160,207|209,209|214,216|221,229|232,234|240,240|245,275|278,279|287,306|311,313|315,322|325,358|364,364|370,370|373,373|375,437|440,442|446,507|510,510|517,518|521,521|528,535|544,584|588,589|595,595|597,601|606,651|654,654|660,676|682,682|694,696|700,700|702,706|714,716|718,737|740,741|748,749|753,754|756,809|815,824|838,838|841,842|844,883|886,887 Q:0,0|3,4|7,7|9,9|43,49|73,73|95,97|107,111|131,131|134,136|158,159|208,208|210,213|217,220|230,231|235,239|241,244|276,277|280,286|307,310|314,314|323,324|359,363|365,369|371,372|374,374|438,439|443,445|508,509|511,516|519,520|522,527|536,543|585,587|590,594|596,596|602,605|652,653|655,659|677,681|683,693|697,699|701,701|707,713|717,717|738,739|742,747|750,752|755,755|810,814|825,837|839,840|843,843|884,885|888,888 E--EE--E?S?--------------------------------HHHHHHH-----------------------T---------------------HHH---------HHHHH?-----------------?S--EEE---------------------EE----???-----------------------------------------S?GGGS?--HHHH??-------TT--?EEEEE?BSST-------------------------------TS??EEEEESS----------------?--?SEEE???S-------?HH----------------------------------HHSBS?EEEEE?SS?E---------------------------------------------------------------EE---EEE----------------------------------------------???------------?TT?HHHHHH--HH-HHHHHH--------HHHHHHHH-----------------------------------------HTT??EEEEE-E?????SGGG----------------------------------------------BS?TGGGT-----------------TSTTS?HHHHHHHHHHH---HTT-E-----EETHHHH???S?-----------------??SB??SSTTTT--TTT??B--------------------------------------------??--------EEEEE----------EGGGGGGEEEEEE?TT??S----------------------------------------SS--B 1VYB|A PF03377.8_Avirulence_seed 2 454 !Q:0,1|28,35|67,69|101,103|135,137|169,171|184,184|203,205|237,239|250,250|272,273|305,307|339,341|373,375|388,388|407,408|441,443 Q:2,27|36,66|70,100|104,134|138,168|172,183|185,202|206,236|240,249|251,271|274,304|308,338|342,372|376,387|389,406|409,440|444,453 ??SHHHHHHHHHSHHHHHHHHHHHHHHH????????HHHHHHHHSSTTHHHHHHHHHHHSHHHHHSS???HHHHTTTTTSTTHHHHHHHHHHHHHHHHHHS???HHHHHHHHSSTTHHHHHHHHHHHSHHHHHHH???HHHHHHHHSSTTHHHHHHHHHHHHHHHHHHT???HHHHHHHHSSSS?HHHHHHHHHHHHHHHTTS???HHHHHHHHSSTTHHHHHHHHHHHHHHHHTTS???HHHHHHHHHH-THHHHHHHHHHHHHHHHTTSS??HHHHHHHHSSTTTHHHHHHHHHHHHHHHTTS???HHHHHHHSSSTTHHHHHHHHHHHHHHHHHHS???SHHHHHHHSSTTHHHHHHHHHHHSGGGTTTT???SHHHHHHHSSTT?HHHHHHHHHHHHHHTTTS??THHHHHHHTTSTTHHHHHHHHHHHSHHHHHHH???SHHHHTTTTS 3V6T|A PF03378.10_CAS_CSE1_seed 16 511 !Q:8,21|39,39|46,47|65,65|69,69|88,90|109,109|115,117|135,135|137,157|164,172|178,183|191,193|195,196|198,198|209,227|233,233|251,251|255,260|262,263|276,276|279,279|296,296|319,320|339,344|375,376|393,393|396,396|403,404|417,419|426,448|452,453|457,464|500,500 Q:0,7|22,38|40,45|48,64|66,68|70,87|91,108|110,114|118,134|136,136|158,163|173,177|184,190|194,194|197,197|199,208|228,232|234,250|252,254|261,261|264,275|277,278|280,295|297,318|321,338|345,374|377,392|394,395|397,402|405,416|420,425|449,451|454,456|465,499|501,510 HHHHHHHH????-?????????HHHHHHHHHHHHHHHTT?SHHHHT??HHHHHHHHHHHTTSTTS?GGG-HHHHHHHHHHHHHHHHTS???HHHHHHHHHHHHHHHHHS?GGGHH---HHHHHHHHHHHHHHHTT?T---------------------TTHHHH---------HHHHH------HHHHHSS---S??T-TTHHHHGGGG------------------?GGGGG?GGGHHHHHHHHHHHHHH?GGG?-----S??HHHHHHHHHHHT?GG-GHHHHHHHHHHHHHHS?GGGTTTTHHHHHHHHHHHHHHH??HHHHHHHHHHHHHHHHHH-----?HHHHHHHHHTTSTTHHHHHHHHTHHHHGGG??SHHHHHHHHHHHHHHH-HS?TTHHHH-?HHHHHHHHHHHH---HHHHTT??-????????????????????GGG??GGG????????TTSBTTBHHHHHHHHHHHHHTTTSSSHHHHHGGGS?HHHHHHHHHH 1Z3H|A PF03388.8_Lectin_leg-like_seed 8 244 !Q:3,3|7,7|9,9|12,12|20,22|30,30|33,34|37,37|42,42|45,46|58,58|60,62|75,78|81,84|93,94|96,98|106,106|109,109|118,118|120,122|125,127|129,129|141,145|154,155|158,161|164,167|170,170|173,173|191,194|199,200|207,208|211,212|217,217|228,229|241,243 Q:0,2|4,6|8,8|10,11|13,19|23,29|31,32|35,36|38,41|43,44|47,57|59,59|63,74|79,80|85,92|95,95|99,105|107,108|110,117|119,119|123,124|128,128|130,140|146,153|156,157|162,163|168,169|171,172|174,190|195,198|201,206|209,210|213,216|218,227|230,240 TTB?GGG?B?TT?TTTSSSS??-SEEEEET?EE?-SS?EEEE?SS--SSEEEEEEESS?B??-SSEEEEEEEEEE????TT????EEEEEEES??S?--EETBTEE?SS?EEEEEEEE?S???TT?-?S?SSEEEEEEEES?????GGGTTGGG??EE----EE?-??BT?SS?EEEEEEEETTEEEEEEE---?SSSS??EEEEEE??EE??SSBE-EEEEEEESSS??EEEEEEEEEEE??? 3A4U|A PF03389.10_MobA_MobL_seed 9 277 !Q:0,1|12,12|25,25|29,31|38,40|43,44|48,51|55,60|71,72|76,76|86,87|91,91|106,106|112,113|120,145|149,149|151,152|162,162|164,164|168,168|170,171|181,215|218,218|244,244|246,276 Q:2,11|13,24|26,28|32,37|41,42|45,47|52,54|61,70|73,75|77,85|88,90|92,105|107,111|114,119|146,148|150,150|153,161|163,163|165,167|169,169|172,180|216,217|219,243|245,245 ??HHHHHHHHHT?EEEETTTTEEEE?TTS?-?SEEEEE?-?TT??GGG----GSH------HHHHHHHHHH??STT?EEEEEEEEE??TTS?HHHHHHHHHHHHHT-TTTTT??EEEEEE?-------------------------TTS-S??EEEEEEESS?B?TTS?B??SEETTEESS-----------------------------------ST-TSHHHHHHHHHHHHHHHHHHHHHTT?S????????----------------------- 2NS6|A PF03391.10_Nepo_coat_seed 11 176 !Q:0,0|6,10|12,12|25,25|28,31|35,36|38,39|42,42|45,45|48,48|65,65|75,75|77,77|80,80|90,90|93,96|105,105|109,109|111,111|119,121|125,125|129,129|131,131|135,135|142,147|153,154|157,158|160,160|173,174 Q:1,5|11,11|13,24|26,27|32,34|37,37|40,41|43,44|46,47|49,64|66,74|76,76|78,79|81,89|91,92|97,104|106,108|110,110|112,118|122,124|126,128|130,130|132,134|136,141|148,152|155,156|159,159|161,172|175,175 ?SEESS???-?S?EEEEEEEEEEEE?SS????EEE??S??SS?EE?SS?EEEEHHHHHHTTBSEE?EEEEEEEEE?S?TT?EEEEEEEEE?SS????HHHHHHSS?EEE?S-SEEEEEE???TTS?EES-S?SSS?EEEEEE------EEEEE??TT??S?EEEEEEEEEEEE?-S 1R1A|3 PF03392.8_OS-D_seed 91 98 !Q:0,1|3,3|7,8|15,15|30,31|34,36|58,58|76,76|88,88|91,91 Q:2,2|4,6|9,14|16,29|32,33|37,57|59,75|77,87|89,90|92,97 ??S?SSS??HHHHHH?HHHHHHHHHHHHSS??TT?-?TTHHHHHHHTTHHHHSTTTTS?HHHHHHHHHHHHHHHHH?HHHHHHHHHHH?TT?TTTHHH 1N8V|A PF03393.11_Pneumo_matrix_seed 9 252 !Q:0,0|7,10|28,29|35,37|41,41|43,43|54,54|75,77|84,84|96,102|105,106|120,121|135,135|138,138|154,155|167,169|176,176|181,181|191,191|205,207|216,216|219,219|225,225|229,229|233,233 Q:1,6|11,27|30,34|38,40|42,42|44,53|55,74|78,83|85,95|103,104|107,119|122,134|136,137|139,153|156,166|170,175|177,180|182,190|192,204|208,215|217,218|220,224|226,228|230,232|234,251 ?EEEEEE????SSEEEEEEEEEEESSSS??EEEEE???EEE?S?HHHHHHHHTT?EEEEEEEEETTEEEEEEEEE???GGGGGS?SEEEEEHHHHB???????BS??EEEEEEEEEEEEE??GGGEEEHHHHTTS?SS?SEEEEEEEEEEETTT??EEEEEEEEEEE???GGGGTT?TTTS?HHHHHHHHT?EEESSSSSEEEEE???SSGGGTTS?TT?EEEEE?GGG?TTS?HHHHHHHEEEEEEEEEEE 2VQP|A PF03398.9_Ist1_seed 44 206 !Q:3,3|37,37|39,55|58,58|96,112|115,116|137,137|152,153|165,167|170,170|172,172|180,182|184,186|203,205 Q:0,2|4,36|38,38|56,57|59,95|113,114|117,136|138,151|154,164|168,169|171,171|173,179|183,183|187,202 HHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?H-----------------HH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHS?----------------SS??GGGHHHHHHHHHHHHHHTTT?HHHHHHHHHHHHHH-?HHHHHHHHTTT---TS?S?HHHHHHT?-?S???HHHHHHHHHHHHHHHT??? 3GGY|A PF03399.11_SAC3_GANP_seed 105 416 !Q:0,9|27,35|40,40|42,44|58,59|65,66|70,73|92,99|104,111|122,122|126,128|137,137|139,139|143,178|180,182|195,195|199,199|201,222|232,232|234,278|281,281|299,300|303,305|308,321|324,327|336,338|340,341|343,359|362,362|371,371|373,373|391,391|393,399|401,403|415,415 Q:10,26|36,39|41,41|45,57|60,64|67,69|74,91|100,103|112,121|123,125|129,136|138,138|140,142|179,179|183,194|196,198|200,200|223,231|233,233|279,280|282,298|301,302|306,307|322,323|328,335|339,339|342,342|360,361|363,370|372,372|374,390|392,392|400,400|404,414 ??????????HHHHHHHHHHHHHHTGG---------GTTT?H---HHHHHHHHHHHHH--HHHTT??SHH----HHHHHHHHHHHHHHHHHH--------HHHS?????---HHHHHHHHHH-HHH---HHHHHHHH-H-HHT------------------------------------T???TTHHHHHHHHHH-HST-T?---------------------THHHHHHTT-S--------------------------------------------?HH-HHTSHHHHHHHHHHHHH??TT???TT??----------??SS????HHHHHHHH---T?-T-----------------TS?HHHHHHHG-G-GHHHHHHHHHHHHHHHS?T-------T???EEHHHHHHHTT? 4BGR|T PF03401.9_TctC_seed 9 281 !Q:15,15|21,23|37,37|46,46|52,52|59,59|61,62|65,65|86,86|89,89|91,92|108,108|132,134|139,139|155,155|157,157|180,180|184,185|192,192|199,200|203,205|217,218|235,235|247,247|250,251|255,255|280,280 Q:0,14|16,20|24,36|38,45|47,51|53,58|60,60|63,64|66,85|87,88|90,90|93,107|109,131|135,138|140,154|156,156|158,179|181,183|186,191|193,198|201,202|206,216|219,234|236,246|248,249|252,254|256,279 HHHHHHHHHHHHHSS?EEEEE???GGGHHHHHHHHTS?SSSSEEEE-EETHH-HHGGGT?S??SS?TTTSEEEEEEEEEEEEEEEE?TT?S??SHHHHHHHHHHHGGG?EEEESSTTSHHHHHHHHHHHHHT???EEEE?SSHHHHHHHHHTTSS?E-EEEEHHHHHHHHHTTSSEEEEE?SSS??TTSTTS?BTTTTT-?TT???EEEEEEEEETT??HHHHHHHHHHHHHHHT?HHHHHHHHHTT?EE?-GGG?SHHHHHHHHHHHHHHHHHHHHHTT? 2QPQ|A PF03403.8_PAF-AH_p_II_seed 7 448 !Q:0,5|9,11|19,31|41,41|43,44|56,58|60,62|64,66|71,72|85,86|94,94|101,101|109,110|112,113|115,116|118,119|127,128|131,132|148,148|154,156|159,159|166,166|176,184|189,193|195,195|225,225|228,232|234,238|240,241|243,247|254,254|260,261|276,282|288,292|295,296|303,305|308,309|314,314|317,318|320,320|330,331|341,362|364,365|369,369|378,379|391,391|401,402|404,404|407,407|429,430|443,443 Q:6,8|12,18|32,40|42,42|45,55|59,59|63,63|67,70|73,84|87,93|95,100|102,108|111,111|114,114|117,117|120,126|129,130|133,147|149,153|157,158|160,165|167,175|185,188|194,194|196,224|226,227|233,233|239,239|242,242|248,253|255,259|262,275|283,287|293,294|297,302|306,307|310,313|315,316|319,319|321,329|332,340|363,363|366,368|370,377|380,390|392,400|403,403|405,406|408,428|431,442|444,447 ??????SSS???SSSSEEE-------------EEEEEESSS-T--TSEEEEEEEEE---S-??S???EESS??HHHHHHHHHHHT??THHHHHH-HHHHTT?EESSEET??B??S--S?-EEEEEEE??TT??TTTTHHHHHHHHHTT?EEEEE???SS?SSEEEE?SSHHHHHHT-------??EEEE?????H-HHHHHHHHHHHHHHHHHHHHHHHHHHHHH-TT?????S-----S??S??---GGGGTT?EEEEE--EEEEEETHHHHHHH-------HHHHH?----TT??EEEEES???TT??GGGG-GG??S?EEEEEETTT??HHHHHHHHT----------------------T??TTS?EEEEEETT??GGGGSGGGGTS?HHHHHHTTS--S?SS?HHHHHHHHHHHHHHHHHHHHT??SSGGGGHHHHTT?STTE 3F98|A PF03404.11_Mo-co_dimer_seed 25 162 !Q:3,4|6,10|18,18|21,21|25,26|28,35|45,45|49,50|64,64|67,67|71,71|79,80|82,83|92,92|96,100|102,102|114,116|120,120|132,133|135,136|138,139|141,144|147,148|150,151|153,153 Q:0,2|5,5|11,17|19,20|22,24|27,27|36,44|46,48|51,63|65,66|68,70|72,78|81,81|84,91|93,95|101,101|103,113|117,119|121,131|134,134|137,137|140,140|145,146|149,149|152,152|154,161 GGB??B???--EEEEEES?TT?EEE??S-------?EEEEEEEEE?STT??EEEEEEESSSSSS?EE?EEE?THHHHHH--T??EEETTEEE?GGG?????S?EEEEEEEEHHH---HHT?SEEEEEEEETT??B??S--S????TT??S??S?EEEEEEEE 2BIH|A PF03405.9_FA_desaturase_2_seed 11 351 !Q:0,0|18,18|24,25|30,31|37,38|42,43|47,49|64,64|91,91|95,96|101,103|131,131|134,134|149,152|154,154|157,157|161,167|195,195|227,227|242,245|250,252|255,255|273,273|280,280|294,299|308,311|331,338|342,342|348,348 Q:1,17|19,23|26,29|32,36|39,41|44,46|50,63|65,90|92,94|97,100|104,130|132,133|135,148|153,153|155,156|158,160|168,194|196,226|228,241|246,249|253,254|256,272|274,279|281,293|300,307|312,330|339,341|343,347|349,350 ?GGGGHHHHHTHHHHHHH-TGGGS??GGGS??GGGGS??TTS--TTH---HHHHHHHHHHHHTS?HHHHHHHHHHHHHHHTHHHHHHHHTT?TTT??SSSS???HHHHHHHHHHHHHHHHHHHHHHHHHHH?SS?HHHHHHHHHHHHHH????S?TT?HHH-------HHHHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHH????TTTT???SS?TTHHHHHHHHHHHHTSS?HHHHHH-HHHHHHHHHTTTS??-???HHHHHHHH----HHHHHHHHHHHHHHHHHTT????---?EEE?GGGTT?EE 2XZ0|A PF03411.8_Peptidase_M74_seed 3 249 !Q:13,13|16,17|19,20|27,27|31,32|36,36|55,57|61,63|65,65|68,75|77,78|82,82|89,92|95,97|104,109|111,111|118,118|122,123|145,145|156,156|159,160|169,169|171,172|181,183|186,186|190,196|199,200|210,236|244,248 Q:0,12|14,15|18,18|21,26|28,30|33,35|37,54|58,60|64,64|66,67|76,76|79,81|83,88|93,94|98,103|110,110|112,117|119,121|124,144|146,155|157,158|161,168|170,170|173,180|184,185|187,189|197,198|201,209|237,243 EEEEETTEEEEES?EE??S??SSEEES?GGG??BEE?HHHHHHHHHHHHHHHHTT???EEE???B?TT????????S??TTS?EEEEES?-??SS???HHHHHS??????B?TTSSSB?TTT??HHHHHHHHHHHHSTTEEEEEE?HHHHHHHHHH?TT??GGGGGEEE?S??SSEEEEEE???TT?TTB???????SS??TTHHHHHTT--??????--??????????----???HHHHHHT????? 1U10|A PF03412.10_Peptidase_C39_seed 36 149 !Q:0,6|11,11|24,25|28,31|41,41|46,47|67,68|71,71|74,74|76,77|80,81|83,83|104,107|117,117|137,137|146,148 Q:7,10|12,23|26,27|32,40|42,45|48,66|69,70|72,73|75,75|78,79|82,82|84,103|108,116|118,136|138,145 ???????SSTT?HHHHHHHHHHHH--TT????HHHHHHHTT?BTTB??HHHHHHHHHHTTEEEEEEE??GG-GG-G?-TT??S?EEEEEEETTEEEEEEEEEEE----ETTEEEEEE?STTTEEEEEEHHHHHHHEE-EEEEEEEE??? 3B79|A PF03413.14_PepSY_seed 348 161 !Q:0,4|9,9|14,22|26,40|42,53|56,56|60,63|70,104|112,112|115,115|118,128|134,142|147,148|154,155 Q:5,8|10,13|23,25|41,41|54,55|57,59|64,69|105,111|113,114|116,117|129,133|143,146|149,153|156,160 ???--HHHH-HHHH---------HHH---------------S-------?----SE-EEE----EEEEEE-----------------------------------TTEEEEE-EE-EE-----------ETTEE---------EEEE--EETTT??EEEEE 2GU3|A PF03414.8_Glyco_transf_6_seed 6 341 !Q:0,57|63,63|67,67|71,72|74,74|77,78|82,82|87,87|100,101|109,109|133,133|142,142|146,152|162,165|191,191|198,198|204,204|206,206|208,208|212,213|220,220|227,227|232,233|235,236|243,244|247,248|250,251|260,260|283,285|301,302|307,307|313,313|317,320|323,324|326,326|331,331|333,333|335,338|340,340 Q:58,62|64,66|68,70|73,73|75,76|79,81|83,86|88,99|102,108|110,132|134,141|143,145|153,161|166,190|192,197|199,203|205,205|207,207|209,211|214,219|221,226|228,231|234,234|237,242|245,246|249,249|252,259|261,282|286,300|303,306|308,312|314,316|321,322|325,325|327,330|332,332|334,334|339,339 ---------------??????????-???????????-----?-----------????GGGTB?GGG?TTS??B?TT??BEE?TTSB?HHHHHHHHHHTT??EEEEEEE?TTHHHHHHHHHHHHHHHHBTTTS?EEEEEEES?GGG???????TTEEEEEEE????SSHHHHHHHHHHHHHHHHHHTHHHH?SEEEEE?SSEEE?S?B?GGG??SEEEEE?TTTSSS?GGGS??B??TTSTTB??TT??S??EEEEEEEE?HHHHHHHHHHHHHHHHHHHHTT???TTHHHHHHHHHHHHS??SEEE?GGGSB?GGG-???TT??S?SEEE?S?S????S? 1G8O|A PF03415.9_Peptidase_C11_seed 7 608 !Q:0,139|147,154|157,157|166,172|175,175|186,187|198,202|210,210|213,215|218,218|220,220|229,229|231,231|234,235|238,257|273,287|311,328|334,342|345,345|350,350|352,394|397,405|417,418|422,422|426,492|495,497|510,510|517,520|527,527|529,532|534,535|537,537|541,544|547,561|570,570|572,578|585,607 Q:140,146|155,156|158,165|173,174|176,185|188,197|203,209|211,212|216,217|219,219|221,228|230,230|232,233|236,237|258,272|288,310|329,333|343,344|346,349|351,351|395,396|406,416|419,421|423,425|493,494|498,509|511,516|521,526|528,528|533,533|536,536|538,540|545,546|562,569|571,571|579,584 -------------------------------------------------------------------------------------------------------------------------------------------?EEEETTE--------EE?HHHHHHHS?------TT?EEEEEEESTT??BHHHHHHTTT-----TEEEEEE?SS???TT?S?HHHHHHHH-T?SS??HH--------------------HHHHHHHHHHHTSSS?------------??EEEEEEGGGHHHHHHHHHHHHTT?----------------?HHHHH---------TS?GGGS?B---------------------------------------????TT???-----?EEEHHHHHHHH??HHH-HHH-------------------------------------------------------------------HH---HHHHHHEEEEEE?SEEEET----TTTEEE-E?--?S??S?EEE????HH---------------HHHHHHHH?H-------HHHHHH?---------------------- 3UWS|A PF03416.14_Peptidase_C54_seed 14 551 !Q:15,17|23,24|26,54|59,59|61,62|66,66|86,86|89,90|94,94|96,147|149,150|164,165|179,208|213,213|215,222|225,228|243,248|252,254|259,259|276,278|280,377|380,381|390,391|395,396|422,422|439,441|446,448|450,450|454,454|456,509|514,515|518,518|527,527 Q:0,14|18,22|25,25|55,58|60,60|63,65|67,85|87,88|91,93|95,95|148,148|151,163|166,178|209,212|214,214|223,224|229,242|249,251|255,258|260,275|279,279|378,379|382,389|392,394|397,421|423,438|442,445|449,449|451,453|455,455|510,513|516,517|519,526|528,550 TTTHHHHHHHHHTSB???EEESS??T-----------------------------TTTS?S??TTT?HHHHHHHHHHHHHHHHHHT?TT??TTS?S----------------------------------------------------S??HHHHHHHHTTSSS--TTSTTSHHHHHHH------------------------------HHTT-T??------TT????HHHHHHHHHHHHTT?-----TTT??-EEEE?BTTEEEHHHHHHHHEE?-?S????????--------------------------------------------????----------????????????-----------------???EE??EEEEEEEE??SSS??GGGHHHHHHHHHSTTEEEEEEEETT-EEEEEEEEETTEEEEE???SEEE???B?TTS?B----------------------------------------------------??GGGB??SS?EEEEGGGS?SEEEEEEEESSHHHHHHHHHHHH 2D1I|A PF03417.11_AAT_seed 18 306 !Q:1,2|5,10|18,19|21,21|35,48|52,53|62,62|64,67|69,69|76,76|81,88|90,92|95,97|102,102|113,114|128,132|137,137|144,144|147,147|161,166|168,170|173,174|180,180|183,208|210,212|215,216|218,227|244,245|247,249|259,260|269,271|278,278|283,285|302,302 Q:0,0|3,4|11,17|20,20|22,34|49,51|54,61|63,63|68,68|70,75|77,80|89,89|93,94|98,101|103,112|115,127|133,136|138,143|145,146|148,160|167,167|171,172|175,179|181,182|209,209|213,214|217,217|228,243|246,246|250,258|261,268|272,277|279,282|286,301|303,305 E??TT??----EEEEEEE--E?GGGGGGEEEEEEE?-------------TTS??EEEEEETT?S--??E-EEETTS?EEEE--------E???BS???TTSB?HHHHHHHHHT-?SSHHHHHHHHHHT----?SBSS?EEEEEE?SS?EEEEEEETTEEEE------E???TT--SEEEE?SS?------------------------?S???TT??B------????HHHHHHHHHHHHHHHS??S?--HHHHHHHTT??TTTTSSSS???BTTTBS?EEEE---EEEEETTTTEEEEEES?TTS 2Z71|A PF03418.9_Peptidase_A25_seed 2 354 !Q:11,25|45,45|55,56|64,66|91,92|95,96|102,102|104,104|111,111|120,123|131,132|135,135|138,140|145,145|150,152|155,155|168,169|179,180|196,196|198,198|200,200|205,208|213,227|235,236|240,242|252,290|293,295|307,307|310,310|341,344|346,349|352,353 Q:0,10|26,44|46,54|57,63|67,90|93,94|97,101|103,103|105,110|112,119|124,130|133,134|136,137|141,144|146,149|153,154|156,167|170,178|181,195|197,197|199,199|201,204|209,212|228,234|237,239|243,251|291,292|296,306|308,309|311,340|345,345|350,351 TTHHHHHHHHH???????????????SEEEEEEEETTEEEEEEEE?HHHHTTTTS??EEEEEEE???SSSSSHHHHHHHHHHHHHHHHHTT??TT??EEEEE?S?SSSGGG?HHHHHHTT????HHHHHHS??SS?SS???EEEE?SGGG???SS?HHHHHHHHHHHH??SEEEEEEEE??SSGGGSSSEEEEETT?B?S?SSSS????BSSS???????????????EEEEEEE??EES???HHHHTTTTT???????????????????????????????????????SS???TTHHHHHHHHT?SS?TTEEEEETTHHHHHHHHHHHHHHHHGGGGS????S????SS?? 1C8B|A PF03422.10_CBM_6_seed 41 157 !Q:3,4|8,9|12,12|17,18|20,20|23,29|34,36|39,39|46,47|53,53|56,56|60,60|69,72|82,85|89,89|97,101|108,114|124,124|126,126|138,138|141,143|145,147|156,156 Q:0,2|5,7|10,11|13,16|19,19|21,22|30,33|37,38|40,45|48,52|54,55|57,59|61,68|73,81|86,88|90,96|102,107|115,123|125,125|127,137|139,140|144,144|148,155 ETT??SEE--ES?EEEE??S-TT-----??EEEE???TT?EEEEEE--EEESS?EE-EEE-EEEEESSS?---EEEEEEESS----TTS?EEEEEEE-??-?SEEEEE-------EEEEEEEEE?S-EEEEEEEEEES?TT---S???EEEEEEEE? 2VZP|A PF03423.8_CBM_25_seed 30 98 !Q:0,1|8,10|12,12|16,16|18,18|28,30|34,34|37,37|43,51|60,60|62,63|66,66|68,68|75,75|77,80|83,83|91,91|95,95 Q:2,7|11,11|13,15|17,17|19,27|31,33|35,36|38,42|52,59|61,61|64,65|67,67|69,74|76,76|81,82|84,90|92,94|96,97 ??EEEEEE---E?SSS-S?EEEEEETTS???SSS?EE?EEETT---------TTEEEEEE-E?-TT?S?EEEEEE?S----SS?EESTTTS?EEE?SE 2LAA|A PF03424.9_CBM_17_28_seed 7 228 !Q:0,36|38,39|45,48|53,53|56,56|59,59|62,62|64,68|73,73|75,76|83,83|89,92|94,95|98,98|105,106|109,109|112,118|121,121|124,125|136,138|147,147|150,155|157,158|162,162|164,164|167,167|170,170|174,174|186,186|195,195|199,199|202,202|212,215|227,227 Q:37,37|40,44|49,52|54,55|57,58|60,61|63,63|69,72|74,74|77,82|84,88|93,93|96,97|99,104|107,108|110,111|119,120|122,123|126,135|139,146|148,149|156,156|159,161|163,163|165,166|168,169|171,173|175,185|187,194|196,198|200,201|203,211|216,226 -----------------------??---------???S??TTSSB?--?TTSS?TT?EE?TT?S-????EEEE?S--SSEEEE?TTTTT????S--SS?GGGSEE--EE?TT---????EE?TT??EEEEEEEESS???EEEEEEEE?SS??????S??EEE?G-GG?EE?TTS?EEEEEEEETTT?HHHHHHHT?TTS?EE?EEEEEEEES----SSEEEEEEEEE? 1G0C|A PF03425.8_CBM_11_seed 15 245 !Q:0,0|8,8|13,23|31,31|40,45|57,60|63,63|69,69|72,72|74,84|86,107|109,110|117,123|126,132|135,138|145,146|161,163|166,167|177,177|180,181|183,185|188,191|194,198|205,205|214,219|231,235|237,245 Q:1,7|9,12|24,30|32,39|46,56|61,62|64,68|70,71|73,73|85,85|108,108|111,116|124,125|133,134|139,144|147,160|164,165|168,176|178,179|182,182|186,187|192,193|199,204|206,213|220,230|236,236 ?BSEEEEE?SSSS??--------?EEEEETT?EEEEEEEE-----?SSSEEEEEEEE--??SS?EEEEE-EE?S??-------??T----------------------T??EEEEEE-------EE???????EE----EEEEEE?-TTSSSEEEEEEEEE???SS-?EEEEEEGGG?EE??S???TT????SS?---?TTSEEE-EEEEESSS??----EEEEEEEEEEE----?B????????- 2LRO|A PF03426.9_CBM_15_seed 2 166 !Q:0,0|2,3|8,8|17,21|24,24|27,27|32,33|44,44|49,49|52,52|61,61|69,69|86,89|91,91|95,100|107,109|112,112|119,120|131,132|144,165 Q:1,1|4,7|9,16|22,23|25,26|28,31|34,43|45,48|50,51|53,60|62,68|70,85|90,90|92,94|101,106|110,111|113,118|121,130|133,143 ?B??SSSS?EEEESSSS?????EE?SS?EEEE??STTEEEEEEE?SSEE?TT?EEEEEEEE?HHHHHTT?EEEEEEEETTEEEEEE????B?GGG??????EEEEEE???SS?TTEESS??EEEEEEEESS??SEEEEEEEEEE?????-------------???? 1US2|A PF03431.8_RNA_replicase_B_seed 6 590 !Q:0,2|5,5|20,23|32,36|38,38|40,40|46,46|58,58|60,62|64,66|68,71|95,106|116,116|125,125|128,129|137,140|143,144|147,148|152,152|161,166|170,170|184,184|186,196|198,200|205,205|214,216|219,220|226,227|250,251|254,254|270,270|282,283|293,293|305,305|310,310|314,314|318,318|322,323|350,351|355,355|381,382|384,384|388,388|393,393|409,415|417,419|442,442|457,457|463,463|466,468|472,472|479,479|483,483|486,486|506,523|537,554|565,571|587,589 Q:3,4|6,19|24,31|37,37|39,39|41,45|47,57|59,59|63,63|67,67|72,94|107,115|117,124|126,127|130,136|141,142|145,146|149,151|153,160|167,169|171,183|185,185|197,197|201,204|206,213|217,218|221,225|228,249|252,253|255,269|271,281|284,292|294,304|306,309|311,313|315,317|319,321|324,349|352,354|356,380|383,383|385,387|389,392|394,408|416,416|420,441|443,456|458,462|464,465|469,471|473,478|480,482|484,485|487,505|524,536|555,564|572,586 ???SS?HHHHHHHHHHHHTT????SSHHHHHS??-??S?S?HHHHH-HHHHHHHTTTT?S???S???H----HHHHHHHHHHHHHHHHHHHHHHT??-?????????HHHHHHHHH-HHHHHHHH?SS??HHHHHHH????SS??SS??GGG?SHHHHHHS-----?EEE?TTTHHHHHHHHHT?S-----------S???EEEE?SEEEEEEE???SS??EEEEE??HHHHHHHHHHHHHHHHHHGGGT??TT?THHHHHHHHHHHHHS?EEEEEBTTGGG??BHHHHHHHS?HHHHHHHHHHS?SEEE?TTS?EEE?SBS??TTSTTHHHHHHHHHHHHHHHHHHHHT??GGG?EEETTEEEEEGGGHHHHHHHHHHTT??B?GGG?BSSS-SEEEETTEEEETTEE???????S???SHHHHHHHHHHHHHHHEETTEE?HHHHHHHHHHHTTS?HHHHH?EE--?TTS?SSSEES?GGG?TT?EEETTEEEEEEEEEEEEEE---------------???HHHHHHHHHHHHH??????????????????HHHHHHHTTS???????EEEEEEEEEEEEEEE??? 3AGP|A PF03433.8_EspA_seed 7 278 !Q:0,33|36,36|61,238 Q:34,35|37,60|239,277 ??---?????????--??????????????????TT?HHHHHHHHHHHHHHHHHHHHHHHT??????????????????????????????????????????????????????????????----???????------------------------------------------------------------------------------------?????????????????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 1XOU|A PF03435.13_Saccharop_dh_seed 82 566 !Q:4,6|24,31|48,58|63,63|68,69|72,72|76,76|81,81|86,88|94,94|96,96|99,100|104,104|115,115|120,124|126,149|161,165|169,169|173,173|175,175|195,223|227,227|234,234|241,244|246,246|250,251|256,257|261,262|269,269|273,275|288,288|296,298|301,302|307,308|314,315|318,318|327,327|330,330|332,334|340,342|355,355|364,365|368,368|372,375|378,379|391,391|407,409|411,411|420,420|432,432|434,437|454,455|458,459|462,462|471,474|477,477|481,481|491,493|496,497|499,501|504,505|528,533|538,538|540,544|561,564 Q:0,3|7,23|32,47|59,62|64,67|70,71|73,75|77,80|82,85|89,93|95,95|97,98|101,103|105,114|116,119|125,125|150,160|166,168|170,172|174,174|176,194|224,226|228,233|235,240|245,245|247,249|252,255|258,260|263,268|270,272|276,287|289,295|299,300|303,306|309,313|316,317|319,326|328,329|331,331|335,339|343,354|356,363|366,367|369,371|376,377|380,390|392,406|410,410|412,419|421,431|433,433|438,453|456,457|460,461|463,470|475,476|478,480|482,490|494,495|498,498|502,503|506,527|534,537|539,539|545,560|565,565 EEEE??-STTHHHHHHHHHTSTTE--------EEEEEESSHHHHHHHH-----------GGGT?EEEE??TT?HHH-HHHH-HHTS---SEEEE?S?GG--GHH-HHHHHHHHHT?EEEE----?S?---------------------??HHHHHHHHHHH-----HHT?EEE?S?BBTTBHHHHHHHHHHHHHH-----------------------------HTT?EEEEEE-EEEEEE----E?GGG??STTS??BSS??HHHHHG-GGS--?EEEEETTEEEEE?TTTHHHH?--EE??SSTT??EEEEE-?SB?THHHHHTT?TT?S---EEEEE---EEEETTHHHHHH-HHHHTTTT??SB?GGG----SS??BHHHHHHHHHT?SSSSHHHHHHHHHTT???S?HHHHHHHH-HHHHHTTTTSS?B????SBHHHHHHHHHHHHSB??TT??EE-EEEEEEEE----EE?TTS?EEEEEEEEE---EE??T---TS??HHHHHHHHHHHHHHHHHHTTSS?----?SEEE?S----?SHHHHHHHHHHHHHHH????E 3IC5|A PF03439.8_Spt5-NGN_seed 64 110 !Q:6,8|11,11|27,27|32,36|38,45|50,50|53,58|69,69|79,79|86,86|89,95|98,101 Q:0,5|9,10|12,26|28,31|37,37|46,49|51,52|59,68|70,78|80,85|87,88|96,97|102,109 EEEEEE?-?TT?HHHHHHHHHHHHHHH-TTSS-----S??-???--EEEE?TT----??SEEEEEESSH-HHHHHHHTT?GGGGGG-SS??-----EE--??GGGTTGGG 3H7H|B PF03440.9_APT_seed 5 88 !Q:0,4|8,8|12,12|15,16|19,21|27,28|35,37|47,47|50,50|62,62|68,68|72,74|84,86 Q:5,7|9,11|13,14|17,18|22,26|29,34|38,46|48,49|51,61|63,67|69,71|75,83|87,87 ?????GGG?EEE?SS--TT???TTEEE??HHHHHH---THHHHHTTS?TT?EEEETTTEEEE?GGGTT?EEE???SSEEEEESS???S 1Z52|A PF03441.9_FAD_binding_7_seed 163 494 !Q:0,0|5,6|12,15|20,21|23,24|26,27|36,37|40,41|43,48|51,98|100,102|112,112|124,124|126,126|133,151|161,161|167,167|175,175|180,199|202,203|209,209|212,212|214,239|241,243|253,253|256,256|271,275|289,289|292,294|301,321|324,334|338,338|341,342|356,357|361,363|366,369|381,381|388,388|395,395|398,398|401,402|405,431|438,442|446,459|461,467|469,474|477,477 Q:1,4|7,11|16,19|22,22|25,25|28,35|38,39|42,42|49,50|99,99|103,111|113,123|125,125|127,132|152,160|162,166|168,174|176,179|200,201|204,208|210,211|213,213|240,240|244,252|254,255|257,270|276,288|290,291|295,300|322,323|335,337|339,340|343,355|358,360|364,365|370,380|382,387|389,394|396,397|399,400|403,404|432,437|443,445|460,460|468,468|475,476|478,493 ?SHHH--HHHHH----HHHH--H--T--HHHHHHHH--TT?-T------TS-----?-----------------------------------------?S???HHHHHHTSS?HHHHHHHHHHH?G-GGGGTS-------------------TTHHHHHHH-HHHHH-HHHHHHH?GGGG--------------------GT??SSGGG-GG-S--???------------------??-H---HHHHHHHHT?SS?HHHHHHHHHHHHHS?--??HHHHHHHHHHHHH-TS???HHHHHH---------------------HH-----------HTT?TT??HHHHHHHHHHHTT-?STT???TT????HHHHHHHHTTT?HHHHHH?GGGTTS?TT-GG--GS---------------------------HHHHHH-----TTT???-----------S-------S??-?--SS?HHHHHHHHHHHHHHHT 2WQ6|A PF03442.9_CBM_X2_seed 41 103 !Q:3,3|9,9|12,17|24,24|26,26|28,34|38,43|45,45|52,53|56,56|62,62|70,76|78,79|88,89|91,91|94,95|97,98 Q:0,2|4,8|10,11|18,23|25,25|27,27|35,37|44,44|46,51|54,55|57,61|63,69|77,77|80,87|90,90|92,93|96,96|99,102 EES?SEEEE?TT??--??EEEEEE?T-T?????--BGG------G?GGGEEE--ET-TEEEE?HHHHHHS------?S--SEEEEEEB??S?TT--T??EEEE 1EHX|A PF03443.9_Glyco_hydro_61_seed 55 345 !Q:0,2|9,10|17,19|26,26|29,35|38,38|40,43|47,48|50,50|61,78|82,88|90,92|94,95|97,98|100,100|103,103|106,106|112,112|115,131|135,140|142,147|154,156|159,160|164,167|171,171|180,183|187,187|192,199|204,213|218,218|228,229|233,234|246,246|251,258|262,271|283,283|286,287|289,308|315,316|319,319|324,327|331,332|334,345 Q:3,8|11,16|20,25|27,28|36,37|39,39|44,46|49,49|51,60|79,81|89,89|93,93|96,96|99,99|101,102|104,105|107,111|113,114|132,134|141,141|148,153|157,158|161,163|168,170|172,179|184,186|188,191|200,203|214,217|219,227|230,232|235,245|247,250|259,261|272,282|284,285|288,288|309,314|317,318|320,323|328,330|333,333 ???EEEEEE--TTEEEE???TTTGGG?SS---????SB?B??-?TTS??B?GGGTTSTHHH------------------HST-------T?--B??S??E-EE?TT?EEEEE-ES--?------------??TTS---???E------EEEEEE?--SS?-GGG??--GGG?EEEEEEEE?---EEE?SSTT?-------EEHH----------HHHH-HTTSEEEEE??SSB??EEEEEEEEEEE?TTTT--------STT--------??EEEEEEEEEEE?SS??B?------------??-?---EEGGGS??TT?TTTS?--?TTS??S------?-???- 3ZUD|A PF03446.10_NAD_binding_2_seed 163 235 !Q:0,0|7,8|20,22|24,24|28,29|34,35|38,39|41,45|53,53|55,57|61,65|72,72|77,77|84,87|90,90|95,95|97,97|109,116|119,120|123,132|135,137|142,142|144,146|157,157|163,165|182,184|190,191|193,193|196,196|204,204|211,211|215,217|223,232 Q:1,6|9,19|23,23|25,27|30,33|36,37|40,40|46,52|54,54|58,60|66,71|73,76|78,83|88,89|91,94|96,96|98,108|117,118|121,122|133,134|138,141|143,143|147,156|158,162|166,181|185,189|192,192|194,195|197,203|205,210|212,214|218,222|233,234 ?BSEEEE??SHHHHHHHHHH---H-HTT??EEEE?-SS--H-----HHHHHHH-H---HHT-----TSSEEE?SSHH-HHHHTB?---SS?EEEE?S?TTHHHHHHHHH--------HT--TT?--------?TT--?EEEE?S???HHHHHHHHHH-HHHHT--?EEEEEEEESHHHHHHH??-EEEEE--E?HH-HHHHHHH-HHHHHS?EET---TEESB?-------??BS 3ORQ|A PF03447.11_NAD_binding_3_seed 30 143 !Q:0,1|15,17|19,24|34,34|41,41|44,44|46,47|52,52|60,62|64,66|77,79|82,83|89,90|92,93|108,108|112,115|121,121|131,132|136,138|141,141 Q:2,14|18,18|25,33|35,40|42,43|45,45|48,51|53,59|63,63|67,76|80,81|84,88|91,91|94,107|109,111|116,120|122,130|133,135|139,140|142,142 ??SHHHHHHHHHHHT???S------SEEEEEEEE?SSBEEE?TT?S??TTTT?HHHHHHH???B???HHHHHHHHTT--?SS-?EEEEE?-S??HHHHTTHHHHHHTT?EEE????TTTSS?SHHHHHHTS??SSS??-EE?G 3FHL|A PF03448.12_MgtE_N_seed 169 126 !Q:0,1|11,16|19,22|24,24|35,36|48,49|52,52|62,64|71,71|77,77|85,87|95,96|108,109|123,123 Q:2,10|17,18|23,23|25,34|37,47|50,51|53,61|65,70|72,76|78,84|88,94|97,107|110,122|124,125 ??HHHHHHGGG------GS---?H-HHHHHHHHHS-?HHHHHHHHHTS?-HH-HHHHHHHHS--?HHHHHH-HHHHS?HHHHHHH---HHHHHHH?-HHHHHHHHHHS-?HHHHHHHHHHHHS?TT 2YVY|A PF03449.10_GreA_GreB_N_seed 134 83 !Q:0,9|46,47|51,51|78,78|80,80 Q:10,45|48,50|52,77|79,79|81,82 ??-----?--EEEEHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHTT??GGG?HHHHHHHHHHHHHHHHHHHHHHHHHH-E-EE 3AOH|X PF03450.12_CO_deh_flav_C_seed 168 127 !Q:3,5|8,8|14,16|28,30|32,41|43,46|62,63|66,67|79,79|82,82|94,94|97,101|103,103|107,107 Q:0,2|6,7|9,13|17,27|31,31|42,42|47,61|64,65|68,78|80,81|83,93|95,96|102,102|104,106|108,126 EEE---EE?SSSSS???SEEEEEEEEEE---T----------T----EEEEEEEEEESSSSS-?EE?-HHHHHTTTTSB?SH-HHHHHHGGGHH-HH?????B-TTB?HHHHHHHHHHHHHHHHHHH 3NVW|B PF03452.9_Anp1_seed 49 357 !Q:0,12|16,19|21,22|29,29|37,40|43,49|59,61|63,65|76,76|97,145|147,147|149,151|156,156|164,182|204,205|215,215|220,221|223,224|235,236|254,255|262,266|268,276|283,283|288,288|291,297|300,300|302,302|307,307|309,309|315,318|322,322|325,326|332,333|347,348|350,353|356,356 Q:13,15|20,20|23,28|30,36|41,42|50,58|62,62|66,75|77,96|146,146|148,148|152,155|157,163|183,203|206,214|216,219|222,222|225,234|237,253|256,261|267,267|277,282|284,287|289,290|298,299|301,301|303,306|308,308|310,314|319,321|323,324|327,331|334,346|349,349|354,355 -????????--??GGG????T--TTTTTT?EEEEEEE?---SS?-----?HHHHHHHHT?-?S?--GGGEEEEEEE?SSHHHHHHHHHHHHHHHHHH-------------------------------------------------T-S?--GGGS?SEEEEEE???????--??????????HHHHHHHHHHHHHHHHHHHHH??TTEEEEEEE?TTEE--E??TTHHHHHHTT??SEEEEEEEEEEEETTTT--EEEEEE?????B?------??HHHHHH-HHTS?TT???---?TT?T-TTTT?S?BGGGG??--TTS?TT??EEESB??SSEEEEEHHHHHT--T????SS? 3ZF8|A PF03453.12_MoeA_N_seed 52 202 !Q:0,0|2,2|14,24|33,33|35,35|37,37|42,42|45,45|48,48|53,53|63,63|70,70|73,87|90,90|99,100|103,105|107,107|109,111|119,119|122,122|124,125|128,129|143,150|155,157|159,161|168,168|174,174|177,177|181,181|184,184|186,187|189,191 Q:1,1|3,13|25,32|34,34|36,36|38,41|43,44|46,47|49,52|54,62|64,69|71,72|88,89|91,98|101,102|106,106|108,108|112,118|120,121|123,123|126,127|130,142|151,154|158,158|162,167|169,173|175,176|178,180|182,183|185,185|188,188|192,201 ?B?HHHHHHHHHHH??????-----EEEEEGGG?T-T?BBSS?EE?SS?BSSS?EESSSEEEE?GGGGTT?BT---------------TB?EEEEEEEE??TT???S-S???TTEEEEE?TT?B??TT??EEEEGGGSEEETT--------EEEE?--S???TTTTEE?TTSSB?TT?EEE?TT?B??H---HHHHHHHHTT 1XI8|A PF03454.10_MoeA_C_seed 47 84 !Q:6,6|9,10|12,12|14,14|23,24|28,31|34,34|39,43|46,52|55,57|62,66|69,69|73,73|76,76|83,83 Q:0,5|7,8|11,11|13,13|15,22|25,27|32,33|35,38|44,45|53,54|58,61|67,68|70,72|74,75|77,82 EEEESS?EE??S-S?BEEEEEEE??TTS----SS?EEEE??---SS???????SB???EEEE?????SS?SEE?TT?EEEEEE? 1XI8|A PF03455.14_dDENN_seed 46 94 !Q:3,3|16,17|23,52|58,60|67,71|80,83 Q:0,2|4,15|18,22|53,57|61,66|72,79|84,93 SBT-HHHHHHHHHHHH--HHGGG????????--????-------------???HHHHS??-SSHHHH-----HHHHHHTT?---HHHHHHHHHH 3TW8|A PF03456.13_uDENN_seed 45 82 !Q:0,1|10,21|23,25|38,38|40,40|48,56|66,66|70,70|73,73|80,80 Q:2,9|22,22|26,37|39,39|41,47|57,65|67,69|71,72|74,79|81,81 ??EEEEEEST------------T???HHHHHHHHHHHS?S?HHHHGGG-------??SEEEEEEEE?TTS?EE-EEEEEE?T 3TW8|A PF03457.9_HA_seed 186 128 !Q:0,5|7,7|15,15|27,29|31,36|39,60|73,76|82,99|101,109|111,113|123,124|126,127 Q:6,6|8,14|16,26|30,30|37,38|61,72|77,81|100,100|110,110|114,122|125,125 ???---S?HHHHHHH-HHHHHHHHHHS---S-----?SS??--------------------SSHHHHHHHHHH----HHHHH------------------T?------??H---HHHHHHHHH--T?? 2KTA|A PF03459.12_TOBE_seed 81 73 !Q:0,0|2,2|16,16|18,20|33,36|45,47|55,56|59,59|66,66|70,70 Q:1,1|3,15|17,17|21,32|37,44|48,54|57,58|60,65|67,69|71,72 ?S?SEEEEEEEEEEEE?S---SEEEEEEEETTS?---EEEEEEEH---HHHHHTT??TT?EEEEEE?GGG?EE 1GUG|A PF03460.12_NIR_SIR_ferr_seed 174 93 !Q:2,2|5,5|9,9|15,16|18,18|20,24|28,29|32,35|45,49|51,52|56,56|58,59|63,63|66,66|70,71|88,88 Q:0,1|3,4|6,8|10,14|17,17|19,19|25,27|30,31|36,44|50,50|53,55|57,57|60,62|64,65|67,69|72,87|89,92 EE?SS-TTE-EEEEE??G-G-----GEE-?HH----HHHHHHHHH-----H--HHS-S--SEE-EE?TTS?-EEEEEEEGGGHHHHHT?HHHH 3MMC|A PF03461.10_TRCF_seed 117 121 !Q:1,5|8,9|11,12|17,18|21,26|38,43|60,60|62,63|83,84|86,86|90,90|94,94|96,99|103,105|108,111 Q:0,0|6,7|10,10|13,16|19,20|27,37|44,59|61,61|64,82|85,85|87,89|91,93|95,95|100,102|106,107|112,120 E?----SS??S??TTTS??HH------HHHHHHHHHHH?----?SHHHHHHHHHHHHHHH?S??HHHHHHHHHHHHHHHHHHH??S?EEE?SSE-E----EEE?-?SS????HHHHHHHHH 2EYQ|A PF03462.13_PCRF_seed 100 173 !Q:0,46|48,51|54,55|58,58|60,60|68,70|79,81|96,96|98,98|100,107|109,112|116,117|121,121|124,124|126,132|142,151|154,163|165,165 Q:47,47|52,53|56,57|59,59|61,67|71,78|82,95|97,97|99,99|108,108|113,115|118,120|122,123|125,125|133,141|152,153|164,164|166,172 ?-??????????---??--???????????-???????????-????S?--?SG--GG-S?EEEEEEE?--SSSHHHHH---HHHHHHHHHHHHHH-H-T--------T????EEE--EEE?TT-S-------SEEEEEEEE?---------SS----------S?HHHHGGG 2B64|Y PF03463.10_eRF1_1_seed 119 216 !Q:1,3|23,25|29,29|36,36|40,40|58,65|70,90|107,108|111,112|115,115|117,152|161,161|163,166|169,170|179,180|182,185|188,189|191,198|205,207|214,215 Q:0,0|4,22|26,28|30,35|37,39|41,57|66,69|91,106|109,110|113,114|116,116|153,160|162,162|167,168|171,178|181,181|186,187|190,190|199,204|208,213 T---TTHHHHHHHHHHHHHHHHT???SSS?EEEEEE?SSS?HHHHHHHHHHHHHHHTT?-----??THHH---------------------HHHHHHHHHHHHHHTT?-SS??TT?E------------------------------------EEEEEEEE?G----GG?-EEEEEEEE??S--??TT??E--------EEEESS???HHHHHH?? 1DT9|A PF03464.10_eRF1_2_seed 35 149 !Q:6,7|10,12|26,31|33,36|39,39|41,41|70,74|76,76|79,79|83,84|99,99|103,103|109,116|118,121|125,125|128,128|140,141 Q:0,5|8,9|13,25|32,32|37,38|40,40|42,69|75,75|77,78|80,82|85,98|100,102|104,108|117,117|122,124|126,127|129,139|142,148 EEEEEE??SS???EEEEETTEEEEEE??????S????SS?S?SHHHHHHHHHHTTTTTTHHHHHTTTTTS?----S-SS?SSS??EEEESTTTTHHHHS?SSS?TTTTT--------T???-EEE?SS?TTHHHHHHHHH--HSSTTTS 1DT9|A PF03465.10_eRF1_3_seed 34 146 !Q:17,18|21,22|38,39|47,50|52,68|70,70|72,74|76,76|79,100|110,110|116,116|121,121|141,141|144,146 Q:0,16|19,20|23,37|40,46|51,51|69,69|71,71|75,75|77,78|101,109|111,115|117,120|122,140|142,143 HHHHHHHHHHHHHHHHS--SS??EEESHHHHHHHHHSS??SEEEEES????B???-?????????????B?T---T?SS???????????--?????????BHHHHHHHT?TTTTS?EEEE?SSSHHHHHHHHTTTTEEEE?SS??- 1DT9|A PF03466.15_LysR_substrate_seed 415 309 !Q:0,8|14,15|20,22|36,36|38,39|41,45|48,48|54,55|57,57|69,69|78,91|101,101|111,113|117,130|135,142|146,147|154,156|162,165|170,176|189,194|196,206|214,214|227,227|238,239|241,247|258,266|268,268|270,270|282,286|288,293|305,305|308,308 Q:9,13|16,19|23,35|37,37|40,40|46,47|49,53|56,56|58,68|70,77|92,100|102,110|114,116|131,134|143,145|148,153|157,161|166,169|177,188|195,195|207,213|215,226|228,237|240,240|248,257|267,267|269,269|271,281|287,287|294,304|306,307 ??????--?EEEEE?-HHHH---TTTHHHHHHHHHH-H-?T-----TS?EEEEE??H-HHHHHHHHTTS?SEEEEESS?-----------??TTEEEEEEE-EEEEEEEEE---TTS--------------GGGG-------?SEE-?GGGGGG--?EEEEE--?-TTSH-------HHHHHHHHHHHT------T???--------EEEEEES?HHHHHHHHHHSS?BEEEETHHHH--H------?TTEEEEEESS?--------S?E-EEEEEEEETTS?-?-?H------HHHHHHHHHHH-HH? 1UTB|A PF03467.10_Smg4_UPF3_seed 6 220 !Q:0,9|14,16|18,18|20,20|30,32|36,54|57,63|67,68|70,74|80,80|84,84|97,100|103,103|106,113|122,219 Q:10,13|17,17|19,19|21,29|33,35|55,56|64,66|69,69|75,79|81,83|85,96|101,102|104,105|114,121 ????????-?EEEE???S?S?HHHHTTTTS?-?SSE-------------------EE???????SSS??S?????EEEES?HHH-HHHHHHHSTTEE----EE?TT------??EEEEEEEE???-----?--?-------------------------------------------------------------------------------------- 1UW4|A PF03468.9_XS_seed 12 132 !Q:0,2|8,8|14,17|20,20|24,24|26,26|28,30|43,45|52,52|54,54|57,57|67,68|89,89|96,96|99,108|110,113|115,115|120,120 Q:3,7|9,13|18,19|21,23|25,25|27,27|31,42|46,51|53,53|55,56|58,66|69,88|90,95|97,98|109,109|114,114|116,119|121,131 ???EEEES?EEEEE????EE?TTS?E-E???SHHHHHHHHHTT???SEEEEE-E?SS-BEEEEEEEE??SSHHHHHHHHHHHHHHHHTT?SHHHHT?SS----------S-???S?EEEE?BHHHHHSSSHH 4E8U|A PF03471.12_CorC_HlyC_seed 174 127 !Q:2,2|6,6|13,13|24,44|46,46|59,62|65,71|74,81|85,85|87,101|104,104|115,116|125,126 Q:0,1|3,5|7,12|14,23|45,45|47,58|63,64|72,73|82,84|86,86|102,103|105,114|117,124 EE?TTS?EEEETT?BHHHHHHHHT?-?----????????-----?S-BHHHHHHHHHSS???-TT?------EE--------EET-T---------------EE-EEEEEEETTE--EEEEEEEE?? 2P3H|A PF03472.10_Autoind_bind_seed 188 184 !Q:4,4|18,18|21,21|26,29|32,34|39,40|46,49|51,51|56,58|69,69|77,79|82,82|84,86|94,94|96,96|98,98|100,113|124,126|135,135|139,139|141,141|144,145|147,147|150,151|157,159|166,167 Q:0,3|5,17|19,20|22,25|30,31|35,38|41,45|50,50|52,55|59,68|70,76|80,81|83,83|87,93|95,95|97,97|99,99|114,123|127,134|136,138|140,140|142,143|146,146|148,149|152,156|160,165|168,183 SHHH-HHHHHHHHHHHTT?SE-EEEE----EE???STTS??EEEEE-???H-HHHH---HHHHTTGGGT?HHHHHHH---HS?S-?-EEEETTT?S-S?H--------------HHHHHHHHTT?-?EEEEEEEE?GGG?E-EE--E-EE--EESSS???HHHHHH--HHHHHHHHHHHHHHHH 3QP5|A PF03473.12_MOSC_seed 30 220 !Q:0,0|6,22|29,29|32,32|36,39|57,57|59,75|81,81|86,90|93,93|95,110|115,116|119,119|123,123|127,129|137,140|162,191|200,200|208,208|215,215 Q:1,5|23,28|30,31|33,35|40,56|58,58|76,80|82,85|91,92|94,94|111,114|117,118|120,122|124,126|130,136|141,161|192,199|201,207|209,214|216,219 ?SSEEE---------------??TTSTTS?TT?EEE????EEEEEHHHHHHHHHHHT?S??--------------?GGGGT?SEEE-----ES?T----------------TGGG??TT?EEE?TTS--?EEEEEEE????HHHHHHHHHHSTTSTTHHHHH------------------------------HHHSTTSS?EEEEEEE?EEEETT?EEEE 1ORU|A PF03475.9_3-alpha_seed 49 50 !Q:1,1|14,18|29,29|32,33|49,49 Q:0,0|2,13|19,28|30,31|34,48 S?BHHHHHHHHHTS???--HHHHHHHHHS-TT??HHHHHHHHHHHHHSS? 1O67|A PF03476.11_MOSC_N_seed 16 171 !Q:0,9|18,19|24,29|32,40|47,47|50,50|52,64|67,67|71,71|76,77|82,94|102,102|104,108|111,111|119,123|126,126|128,128|144,145|147,156|161,161|168,168 Q:10,17|20,23|30,31|41,46|48,49|51,51|65,66|68,70|72,75|78,81|95,101|103,103|109,110|112,118|124,125|127,127|129,143|146,146|157,160|162,167|169,170 ----------EETTTEEE??GGGG------GT??-------SEEEEE-TT-S------------?EE?TTT?GGGG??EEEE?------------SSEEEEE?S-----SS?EEEEESS--???SS?S?EEEEEETTEEEEEEE??H----------HHHH-HHHHHT?SS 2EXN|A PF03477.11_ATP-cone_seed 133 143 !Q:0,14|26,26|29,43|45,45|47,51|54,57|69,72|74,81|83,85|101,113|117,117|119,123|134,135 Q:15,25|27,28|44,44|46,46|52,53|58,68|73,73|82,82|86,100|114,116|118,118|124,133|136,142 ????????-??????HHHHHHHHHTT?TT---------------S?T-----TT?-?-THHHHHHHGGG--??T--------T?-?HHHHHHHHHHHHHHG-------------GGT?T-----HHHHHHHHHH--HHHHHHH 3PAW|A PF03479.10_DUF296_seed 113 174 !Q:0,0|7,8|12,28|37,39|46,47|52,52|57,57|70,71|73,76|78,84|87,88|90,91|97,98|100,100|112,121|123,123|138,139|155,156|166,166|169,171 Q:1,6|9,11|29,36|40,45|48,51|53,56|58,69|72,72|77,77|85,86|89,89|92,96|99,99|101,111|122,122|124,137|140,154|157,165|167,168|172,173 ?EEEEEE??TTS-----------------BHHHHHHH---HHHHHT??SEEE-EEEE-EEEEEEEEEEET--T----T-------TE--E--EEEEE-?S?EEEEEEEEEEE----------E-ETTEEEEEEEEEEE--EBTEEEEEEEEEEEE--EEEEEEEEE?BS???BE 3HTN|A PF03480.8_SBP_bac_7_seed 35 338 !Q:2,5|16,16|27,27|33,34|40,45|47,52|61,67|82,82|89,90|102,103|115,115|123,124|136,136|141,142|156,156|158,158|160,161|170,172|176,177|195,197|210,210|216,216|221,221|230,231|238,239|243,245|261,261|298,302|305,305|309,309|314,314|319,319|329,331|335,335 Q:0,1|6,15|17,26|28,32|35,39|46,46|53,60|68,81|83,88|91,101|104,114|116,122|125,135|137,140|143,155|157,157|159,159|162,169|173,175|178,194|198,209|211,215|217,220|222,229|232,237|240,242|246,260|262,297|303,304|306,308|310,313|315,318|320,328|332,334|336,337 EE???-STTSHHHHHH-HHHHHHHHHH-TTTSE--EEEEE?--???S????-?HHHHHHHT?------SEEEEEEHHHHTTT-SGGGGG--GGSTTHHHHTT??SHHHHHHHHHH-HHTSHHH--HHHHHHHHHHH?EEEE--EEEEEEEEEEEEE-S-S??SSGGGGTT--?EEE??SSHHHHHHHHHHTSEEE???GGGHHHHHHTTS?SEEEE?HHHH-HHTTGGGT??EEEEEE--EEE---EEEEEEEEHHHHHHS?HHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHH-----TT?EEE?GGGS?HHHH-HHHHHHHHH---HHT?HH 2XWV|A PF03481.8_SUA5_seed 384 359 !Q:1,1|5,6|9,10|13,13|16,25|27,78|83,90|92,93|96,106|109,121|124,126|129,129|137,173|176,176|189,222|226,228|231,236|238,253|257,267|269,269|272,272|290,300|302,310|317,335|337,339|342,343|345,345|356,356 Q:0,0|2,4|7,8|11,12|14,15|26,26|79,82|91,91|94,95|107,108|122,123|127,128|130,136|174,175|177,188|223,225|229,230|237,237|254,256|268,268|270,271|273,289|301,301|311,316|336,336|340,341|344,344|346,355|357,358 S?HHH--HH--HH?TT?---------B?------??????-----??---???--??---------?-???????????SSEE--------E--EE---------??GG-------------GH---HH-HHHHHHH-------------------------------------HS?EEEEEEGGGTGG----------------------------------GTT---SE------E----------------EEE-----------E?TT?HHHHHHHHHHHHHHHHH-----------S------??-SEEEEE--------?--??-?----T---TT--H-HHHHHHHHHH-TT 3AJE|A PF03483.12_B3_4_seed 308 269 !Q:1,1|8,8|13,14|17,20|27,28|34,39|54,60|69,83|85,87|89,89|92,96|99,105|110,111|115,115|118,121|123,149|151,152|154,154|157,166|168,173|175,175|177,177|180,180|186,187|193,195|197,205|207,209|217,218|231,235|244,247|250,250|267,267 Q:0,0|2,7|9,12|15,16|21,26|29,33|40,53|61,68|84,84|88,88|90,91|97,98|106,109|112,114|116,117|122,122|150,150|153,153|155,156|167,167|174,174|176,176|178,179|181,185|188,192|196,196|206,206|210,216|219,230|236,243|248,249|251,266|268,268 T?SEEEEE-EEES??TT????THHHHH--HHHTT???-??SHHHHHHHHHHHHS?-----?EEEEEGGG?----?---------S-??E-EE?-??-SS----?-?EEET--TTE-EE??-?T---------------------------T??E-EE---?------S------S-S-EE-EETTT??BSTTB??-T---------T???EEEEEEE??GGGSTTHHHHTT--???HHHHHHHH?-??TT?HHHHHHHHHHHHHTTS-S 2IY5|B PF03484.10_B5_seed 85 123 !Q:0,1|16,42|44,48|55,57|64,64|69,88|97,98|101,103|106,106|121,121 Q:2,15|43,43|49,54|58,63|65,68|89,96|99,100|104,105|107,120|122,122 ??EEEEEHHHHHHHHS---------------------------S--???HHHHHH---HHHHHT?EEEE--------------------ETTEEEEE??SS?--SS?SSHHHHHHHHHHHH?G 2IY5|B PF03485.11_Arg_tRNA_synt_N_seed 174 130 !Q:0,1|14,20|26,29|32,35|38,38|40,47|53,53|58,59|70,77|88,90|92,94|96,99|102,107|110,111|119,122 Q:2,13|21,25|30,31|36,37|39,39|48,52|54,57|60,69|78,87|91,91|95,95|100,101|108,109|112,118|123,129 ??HHHHHHHHHHHH-------HHHTT?--?TT????EE-E--?-----SSGGG?SEEE??HHHHHHHTTS-------?HHHHHHHHHH---H???T----TT------EE--EEEEETT----TEEEEEE 3GDZ|A PF03486.9_HI0933_like_seed 49 447 !Q:0,0|6,7|19,20|25,26|31,31|37,37|48,50|53,55|57,57|65,65|76,76|81,81|94,95|99,99|109,111|126,126|129,129|133,133|135,136|141,148|161,161|163,166|168,170|174,174|176,176|180,183|191,191|204,205|212,212|214,215|218,221|232,232|242,257|268,268|292,293|295,295|303,303|307,307|331,332|338,338|351,353|358,358|363,363|382,382|385,386|390,390|398,398|418,418|424,424|426,427|447,447 Q:1,5|8,18|21,24|27,30|32,36|38,47|51,52|56,56|58,64|66,75|77,80|82,93|96,98|100,108|112,125|127,128|130,132|134,134|137,140|149,160|162,162|167,167|171,173|175,175|177,179|184,190|192,203|206,211|213,213|216,217|222,231|233,241|258,267|269,291|294,294|296,302|304,306|308,330|333,337|339,350|354,357|359,362|364,381|383,384|387,389|391,397|399,417|419,423|425,425|428,446 ?SEEEE??SHHHHHHHHHH--HHTT??EEEE?SSSSS?HHHHHTGGGT???EE--?S?HHHHHHT?TBTGGGGHHH-HHHS?HHHHHHHHHHTT??EEE?GGGEEEETT?-?HHHHHHHHHHHHHH-TT?EEE?S??EEEE--------EEETTEEEEEEE-T----T??-EEE?S?EEE????SSSGGGS?SSHHHHHHHHTT??EEEEEE?S??EE??-?HHHHTTTTTT?EEEEEEEEE??---------?????EEEEEEEEEE?SSEEESHHHHHHHHHHHHHHHHH??S?EEEEEES?TTS?HHHHHHHHHHHHTTSTTSBHHHH--TTTSS?HHHHHHHHHHTT?-?TTSB-GGGS?HHHHHHHHHHHHHEEEEE?EE??GGG?SSEEEEE?GGGEETTTTEESSSBTEEE?GGGBS?B??TTTHHHHHHHHHHHHHHHH- 2JB3|A PF03487.8_IL13_seed 4 47 !Q:0,24|27,30|46,47 Q:25,26|31,45 ?????????????????????????SH----HHHHHHHHHHHHHHS?- 3G6D|A PF03488.9_Ins_beta_seed 11 51 !Q:0,2|16,16|21,23|25,25|36,40|49,50 Q:3,15|17,20|24,24|26,35|41,48 ???SHHHHHHHHHHHT-SSSS???S?TTHHHHHTTT?--??HHHHHHHH?? 2KJI|A PF03489.12_SapB_2_seed 103 38 !Q:0,0|22,25|32,32|36,37 Q:1,21|26,31|33,35 ?HHHHHHHHHTHHHHHHHHHTT??--HHHHHH-HTT?? 2JS9|A PF03492.10_Methyltransf_7_seed 23 384 !Q:8,11|16,17|24,25|30,31|56,60|63,64|73,73|77,77|89,89|91,105|108,108|117,117|121,122|124,124|127,127|130,130|136,136|140,140|143,144|146,161|168,168|172,177|181,182|203,203|206,206|215,215|218,223|233,234|252,252|254,255|262,265|267,269|284,285|293,297|302,304|307,307|310,317|344,344|367,371|383,383 Q:0,7|12,15|18,23|26,29|32,55|61,62|65,72|74,76|78,88|90,90|106,107|109,116|118,120|123,123|125,126|128,129|131,135|137,139|141,142|145,145|162,167|169,171|178,180|183,202|204,205|207,214|216,217|224,232|235,251|253,253|256,261|266,266|270,283|286,292|298,301|305,306|308,309|318,343|345,366|372,382 HHHHHHHH----HSSS--SSSSEE??EEES??SSTTTTTGGGTTHHHHHHHHHSSS----?SS??EEEEEEEE?TTS?HHHHHTTTTTS?S?--------------TT?EEEEEEES?SSS??S?TT?BS?EEEES?TTB?SS??S????-----------?TTTTSS?SSS??----TTS??SHHHHHHHHHHHHHHHHHHB?TT?EEEEEEEE?SS------SSSSSTTTS--TTTHHHHHHHHHHHHTT?S??STTGGG????B???SHHHHHHHHHTTTB??EEEEEEE-----EETT-??SS?TT??------SSTTTTTTHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHHHHSS?---?EEEEEEEEEEB? 2EG5|A PF03493.13_BK_channel_a_seed 35 121 !Q:1,1|4,5|10,11|43,55|57,68|81,82|87,89|93,96|99,99|113,115 Q:0,0|2,3|6,9|12,42|56,56|69,80|83,86|90,92|97,98|100,112|116,120 G?TT??TTTT-?EEEEHHHHHHHHHHHHHHSTTHHHHHHHHHS???-----?????S-----------?SHHHHHHHHHTB??EEEE?-?GGG----TT?BHHHHHHHHHHHT???EEEEE 3NAF|A PF03494.8_Beta-APP_seed 2 39 !Q:0,13|24,25|38,38 Q:14,23|26,37 ??????????????EEEEEEEEES??SEEEEEEEEEEE? 2OTK|C PF03495.9_Binary_toxB_seed 8 463 !Q:0,3|10,10|17,17|32,44|46,48|51,51|60,60|68,68|70,70|74,74|83,87|100,102|105,118|128,162|170,171|173,174|178,184|191,192|195,195|208,208|212,212|214,214|216,219|229,231|237,239|242,243|246,246|248,248|255,255|259,260|265,268|271,273|284,284|289,289|296,300|337,337|342,343|350,350|352,352|362,363|375,378|380,381|386,386|389,391|394,399|406,408|413,413|429,434|436,436|440,440|444,444|450,450|462,462 Q:4,9|11,16|18,31|45,45|49,50|52,59|61,67|69,69|71,73|75,82|88,99|103,104|119,127|163,169|172,172|175,177|185,190|193,194|196,207|209,211|213,213|215,215|220,228|232,236|240,241|244,245|247,247|249,254|256,258|261,264|269,270|274,283|285,288|290,295|301,336|338,341|344,349|351,351|353,361|364,374|379,379|382,385|387,388|392,393|400,405|409,412|414,428|435,435|437,439|441,443|445,449|451,461 ?-??TTSSSS?HHHHHH?EEEEEETTEEEEEE?????????????B???TT?SSTTSSSS?HHHHHHT?S?TTS?GGGGSTTB?????EEEEEEEEEEEE???TT??????----????EEEEEEEEE??????????????????-----????????????EEEEEEE??S??SSS??----?HHHHHT??TT?EEEEEEEEEEEE?SSS?B?S????EEEEETTTE---EEEEE???TT??SS?B?TTEEES?TTS??EESS????TT???EEEEHHHHHH-HHHH?EEEEEE?????EEEEEETTTTEEEEEEEEEGGGTHHHHHHHEEEEEE?TTTT??EEEEEE?B?TTSTGGGGS??EEHHHHHHHHH--??B?-SSSS?EE---TT------EEGGGE---EEEE?HHHHHHHHHHHHHTT?-----S?GGG?TTT?EEBTT?EEEEEETTSEE? 1ACC|A PF03496.9_ADPrib_exo_Tox_seed 26 307 !Q:15,38|62,63|69,74|76,76|78,80|104,108|110,110|118,118|123,123|125,131|136,138|142,143|147,149|163,163|168,168|170,170|179,186|195,195|204,204|207,208|212,212|215,216|218,248|251,252|256,256|261,261|269,278|285,295|304,306 Q:0,14|39,61|64,68|75,75|77,77|81,103|109,109|111,117|119,122|124,124|132,135|139,141|144,146|150,162|164,167|169,169|171,178|187,194|196,203|205,206|209,211|213,214|217,217|249,250|253,255|257,260|262,268|279,284|296,303 HHHHHHHHHHHHHHT?-----------------------BHHHHHHHHHHHTTTHHHHHHHH--HTTTT??????S-S???HHHHHHHHHHHHHHHHHHHHHHT?-???S?EEEEEEE?GGGG?G-------GGTT???EET--TEE?--HHHHHHHHHHHTT?EEEE?S?EEEESSSS-------?STTSSTTT?SEEEEEEE?TT??EEE?GG--G-------------------------------SS?-GGG?EEEE?TTEEEEE----------EEEEEE???????????EEEEEEEE??? 4FK7|A PF03497.11_Anthrax_toxA_seed 7 209 !Q:0,2|4,7|17,19|22,23|42,45|56,57|60,61|64,69|75,76|80,80|89,95|99,99|117,122|132,132|134,135|148,148|151,153|166,166|168,168|180,183|190,190|193,199|203,206 Q:3,3|8,16|20,21|24,41|46,55|58,59|62,63|70,74|77,79|81,88|96,98|100,116|123,131|133,133|136,147|149,150|154,165|167,167|169,179|184,189|191,192|200,202|207,208 ???E----ESHHHHHHH???HH--HHHHHHHHHHHTTEEEEE????GGGHHHHHHT?-EE??SS??????SSSTT--TTB?BSSTTSST-------TTT?HHHHHHHHHHHHHHHHH------TBTTEEEEE?B??HHHHHHHHHTTS?EE???EEETTEEEEEEE?S?SSEEEEEETTT?---BEEEEE?SS?----??TTS????SE 1SK6|A PF03498.9_CDtoxinA_seed 10 173 !Q:0,0|6,6|15,15|17,17|21,21|24,26|34,34|42,42|48,48|53,53|62,64|69,71|80,84|87,91|95,95|105,105|111,112|116,117|122,122|125,125|128,131|133,133|135,135|140,146|148,150|156,157|162,166|169,169 Q:1,5|7,14|16,16|18,20|22,23|27,33|35,41|43,47|49,52|54,61|65,68|72,79|85,86|92,94|96,104|106,110|113,115|118,121|123,124|126,127|132,132|134,134|136,139|147,147|151,155|158,161|167,168|170,172 ?BEEEE-TTSEEEEE?S?STT?BE---EEEEGGG?GGGGGGG?EEEEE?SSTT?EEEEETTT??-EEEE---ETTEEEEE?--??TT----?GGG?EEEEEBTTS?EEEEE--TTT??EEEE?SS?SS----S?B?EEEE??--???E---ETTEE??EEEE??---SS?EEB 1SR4|A PF03500.8_Cellsynth_D_seed 2 144 !Q:0,0|36,40|59,60|67,67|79,83|86,86|92,92|114,114|117,118|121,121|130,131|134,134 Q:1,35|41,58|61,66|68,78|84,85|87,91|93,113|115,116|119,120|122,129|132,133|135,143 ?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTB?????SSHHHHHHHHHHHHHHHT??EEEEEE?TTTSEEEEEEE?????SS?TTTTT?TTHHHHHHHHHHHHHTSTTBS?SS??EE?HHHHTTTT??TT?EEEEEEBSS 3AJ1|A PF03501.10_S10_plectin_seed 39 109 !Q:0,1|20,21|23,23|26,28|30,30|33,40|42,43|46,46|68,68|73,73|78,78|91,92|95,98|100,108 Q:2,19|22,22|24,25|29,29|31,32|41,41|44,45|47,67|69,72|74,77|79,90|93,94|99,99 ??TTHHHHHHHHHHHHSEEE??S?SS??-S?SS--------S??SS?STTTHHHHHHHHHHTSSEEEE?TTTT?EEEE?HHHHHHHHHHHT??TT-???S????????? 2XZM|7 PF03502.8_Channel_Tsx_seed 44 333 !Q:0,0|17,17|20,23|26,26|28,33|57,78|95,97|107,113|121,136|142,151|155,158|168,169|189,195|197,197|200,201|211,211|226,226|238,240|246,246|248,248|256,256|258,258|270,271|275,281|297,297|300,300|307,307|309,314|317,319 Q:1,16|18,19|24,25|27,27|34,56|79,94|98,106|114,120|137,141|152,154|159,167|170,188|196,196|198,199|202,210|212,225|227,237|241,245|247,247|249,255|257,257|259,269|272,274|282,296|298,299|301,306|308,308|315,316|320,332 ?TTTEEEEEEEEEEESB?SS----SS?B?----?EEEEEEEEEEETTEEEEEEEEEE???--?????????????-???EEEEEEEEEHHHHHTS???BTTEEEEEE-------EEEEEEE?--------------?SSSSS---------?EEE----EEEEEEEEE??SSSSEEEEEEEEEEEEEET-------T?TT?-SEEEEEEEE-EEEEEEEEEETTEE-EEEEEEEEEEE???TTTSS?B?TTSSBSB?S?EEEEEEEEEEE-?SSE-------EEEEEEEEEESGGGB?TT?EEESSS?E------EE???SEEEEEEEEEEEE 1TLY|A PF03505.9_Clenterotox_seed 4 198 !Q:10,10|13,13|20,21|24,24|26,28|34,34|39,39|52,55|59,61|69,70|74,74|81,82|92,92|106,106|108,108|115,117|119,119|121,129|131,131|135,135|137,140|146,147|151,151|154,154|156,157|159,159|161,161|168,169|173,173|176,176|186,186|197,197 Q:0,9|11,12|14,19|22,23|25,25|29,33|35,38|40,51|56,58|62,68|71,73|75,80|83,91|93,105|107,107|109,114|118,118|120,120|130,130|132,134|136,136|141,145|148,150|152,153|155,155|158,158|160,160|162,167|170,172|174,175|177,185|187,196 TTTEEEEEEE?TT?EEEEEE??SS?B???EEEES?TTTS?HHHHHHHHHHHH????SSB???EEEEEEE??SSS?EEEEEE??EEEEEEEEE?SSSEEEEEEEEEE?S?EEEEEE???S?S?????????S?EEE?S????EEEEE??TTS?EE-E??B?B?SEEEEE??GGG?SS?EEEEEEBSS?EEEEEEEGGG? 3AM2|A PF03507.8_CagA_seed 4 195 !Q:0,81|83,88|91,91|94,195 Q:82,82|89,90|92,93 --------------????????????????????????????????????????????????????????????????????B??????BS?TT????????????????--???-?????????????????????????-----------------------------------------------------?- 3IEC|E PF03508.8_Connexin43_seed 3 20 !Q:0,0|3,3|8,11|13,13|15,15|18,19 Q:1,2|4,7|12,12|14,14|16,17 ?SS?SSSS????S?S?SS?? 1R5S|A PF03513.9_Cloacin_immun_seed 6 82 !Q:0,0|13,14|21,24|27,28|36,37|45,45|49,50|61,61|64,66|79,79 Q:1,12|15,20|25,26|29,35|38,44|46,48|51,60|62,63|67,78|80,81 ?EEEEEEEEETTT??EEEEEE????TT??HHHHHHT??STTTTTS?EEE??TTHHHHHGGG?SS???TTTEEEEEEEEE?SS 1E44|A PF03515.9_Cloacin_seed 8 434 !Q:0,114|118,124|126,126|131,132|134,140|143,150|158,158|160,163|165,166|179,208|212,212|221,221|225,227|232,251|266,266|271,271|274,274|281,281|291,291|300,301|303,303|311,311|314,322|327,327|331,333|336,336|338,339|348,352|354,355|361,367|369,370|372,372|375,376|385,386|392,393|397,401|409,411|416,418 Q:115,117|125,125|127,130|133,133|141,142|151,157|159,159|164,164|167,178|209,211|213,220|222,224|228,231|252,265|267,270|272,273|275,280|282,290|292,299|302,302|304,310|312,313|323,326|328,330|334,335|337,337|340,347|353,353|356,360|368,368|371,371|373,374|377,384|387,391|394,396|402,408|412,415|419,433 ???????-----??????????????????????????--????????????????????????????????-???????--?????????------------------??????EET-------T?EEEE??B-------TT--------BEEEEEE?S----S??HHHHHHHHHHTS-------?---------------------?SSS?EEEEEEEE?GGG???SSSS?-----------------??EEEEEEEHHHHBSS?GGGS?TT?SEEEES?EEEEEESSS?EEEEEEES--S?EEEEEEE?EE--------?SSTT?EEE??-TT-S??EEEEEESS?????S??TTEES?------S??S?EE??TTTTTTEE--EEEEE??GGG????-EEEEEEE???HHHH---HHHHHHHHHHHHHHH 1JCH|A PF03517.8_Voldacs_seed 115 303 !Q:8,8|14,14|16,21|23,59|69,71|76,77|80,80|82,103|105,106|108,109|116,119|122,122|124,184|187,189|191,192|195,196|198,198|209,209|211,242|245,250|264,302 Q:0,7|9,13|15,15|22,22|60,68|72,75|78,79|81,81|104,104|107,107|110,115|120,121|123,123|185,186|190,190|193,194|197,197|199,208|210,210|243,244|251,263 EEEEEETT-EEEEE-E------T-------------------------------------TTEEEEESS???SEEE??SS?S----------------------S??S??EEEEEE????SS?S-------------------------------------------------------------SS???S??SS??S?SEEEEEEEES?H--------------------------------HH------HHHHHHHHHHHHH-??????----?????????????????????-----?? 1ZYI|A PF03519.9_Invas_SpaK_seed 7 85 !Q:1,2|7,10|20,20|24,25|35,37|44,45|66,69|77,77 Q:0,0|3,6|11,19|21,23|26,34|38,43|46,65|70,76|78,84 T??GGGB????SSSEEEEEE-SSS??EEEEEETTE---EEEEEE??TTHHHHHHHHHHHHHHHHHT??--TTBGGGS?EEEEETT 2XGA|A PF03520.9_KCNQ_channel_seed 9 232 !Q:0,77|101,231 Q:78,100 -----------------------------------?---------------------------------------???HHHHHHHHHHHHHHHHHHHHHHH??????????????????????????????????????????----------------------------------------------------------------------------------------? 3BJ4|A PF03524.10_CagX_seed 150 397 !Q:0,50|52,58|60,103|105,139|142,149|154,167|169,169|172,212|214,278|280,282|287,288|294,295|297,298|301,301|305,305|308,308|313,314|317,317|319,325|331,331|333,335|338,342|344,344|347,349|356,360|363,363|370,371|374,374|381,384|387,387|394,394|397,397 Q:51,51|59,59|104,104|140,141|150,153|168,168|170,171|213,213|279,279|283,286|289,293|296,296|299,300|302,304|306,307|309,312|315,316|318,318|326,330|332,332|336,337|343,343|345,346|350,355|361,362|364,369|372,373|375,380|385,386|388,393|395,396 --------------------------------------------------?H-------H--------------------------------------------H-----------------------------------HH--------HHHH--------------H-HT???-------------------------------------?S-------------------------------------?--------------------------?B??-EEEE??GGGGG--G??SE-EEE?SS?EEEE??TT-S?----??EEEEE?T---TS-----S-EE???EEEEST-----TS?EEEESS??SE-EEEEET----TE-EEEEEE-TT- 3JQO|B PF03531.9_SSrecog_seed 6 228 !Q:0,137|140,140|161,161|169,169|189,189|223,223 Q:138,139|141,160|162,168|170,188|190,222|224,227 ------------------------------------------------------------------------------------------------------??---------------???????????????????TT?SEEEEEEEEEETTEEEEEEE?SSEEEEE?SSBEEEEEGGGEEEEEEEE?TTSSEEEEEEEEEEEEESSSSEEEEEEEEEETT?EEEE 3F5R|A PF03534.8_SpvB_seed 17 357 !Q:1,4|7,9|15,19|23,30|38,41|49,52|57,58|62,64|69,75|78,78|82,82|87,87|89,90|96,96|101,101|126,127|140,153|159,159|163,163|169,169|177,177|180,184|186,186|199,200|204,204|213,215|218,219|226,237|239,243|256,257|260,260|266,269|271,273|276,277|279,287|300,302|306,308|311,321|324,328|331,331|335,335|340,340|344,348|355,355 Q:0,0|5,6|10,14|20,22|31,37|42,48|53,56|59,61|65,68|76,77|79,81|83,86|88,88|91,95|97,100|102,125|128,139|154,158|160,162|164,168|170,176|178,179|185,185|187,198|201,203|205,212|216,217|220,225|238,238|244,255|258,259|261,265|270,270|274,275|278,278|288,299|303,305|309,310|322,323|329,330|332,334|336,339|341,343|349,354|356,356 E????TT???EEEEE?????TTS---?????EEEEETT????TTSTTEE????EEEB??TTS???SSTT-----??BB?TTS?BEEE?B-?TTSSB?EEEE-EEETTEEEEEEEEEEEEEESEESS??EEEEEEESSGGG?-----------??EEEEE?TBS?EEEES?SGGGEEE?SS----?T-TSEEEEEEEEEE?-TTS?EEEEEEEE???TT??HHHHHH?-----------S?????EEEEEEEEEESS??SS?GGGSS----S???GG--G---------EEEEEEEESSSS???TTS???SS?-?--------SS?????SS?EEE?TTSS?EEE?????EEEEEE?H 4IGL|A PF03536.10_VRP3_seed 3 240 !Q:0,26|46,53|56,58|65,68|78,79|90,91|94,95|97,99|106,106|108,108|125,125|128,128|130,131|137,137|146,148|151,151|157,159|165,167|190,191|193,196|199,199|201,202|205,205|215,221|231,231|239,239 Q:27,45|54,55|59,64|69,77|80,89|92,93|96,96|100,105|107,107|109,124|126,127|129,129|132,136|138,145|149,150|152,156|160,164|168,189|192,192|197,198|200,200|203,204|206,214|222,230|232,238 ???????????????????????????HHHHHHHTHHHHHHHHHTS????????SS???HHHHHT????EEETTEEEE??SSSSEEEEEE??TT??S???SEEEEE?B?GGGHHHHHHHHHHHHT?TT?S??EEEEE?HHHHHHTT???SS?SEEEE???SSTTS???HHHHHHHHHHHHHHHHHHHHTT??B????TT?B??TT?SSEEEEETT???????HHHHHHHHT?HHHHHTT? 2Z8O|A PF03537.8_Glyco_hydro_114_seed 128 173 !Q:0,17|19,20|24,24|26,34|36,45|52,62|64,71|77,77|80,80|85,90|95,101|108,108|110,111|115,117|119,123|137,142|147,148|150,150|152,152|154,158|160,163|165,168|170,171 Q:18,18|21,23|25,25|35,35|46,51|63,63|72,76|78,79|81,84|91,94|102,107|109,109|112,114|118,118|124,136|143,146|149,149|151,151|153,153|159,159|164,164|169,169|172,172 ???????--?--------S??EEE?S---------S?--------?HHHHHT-----------S??------SEEEE?SB-SSSS------GGGB??-----HHHHHH-H--HHT---T----?EEEEEEESSEEET------TSTT??T-H-H-----H----H----S??T 2AAM|A PF03539.9_Spuma_A9PTase_seed 4 163 !Q:10,10|13,13|26,28|36,36|39,39|55,55|72,72|76,76|82,162 Q:0,9|11,12|14,25|29,35|37,38|40,54|56,71|73,75|77,81 ETTEEEEEEE?TT?SSEEEEGGGTTT???SEEEEEE?SS?EEEEEEEEEEEEESS?EEEEEEEEESSSSEEE?TTT?HHHHS??????-----??????---------------------------------------------------------------- 2JYS|A PF03543.9_Peptidase_C58_seed 14 268 !Q:0,2|4,6|14,17|20,46|55,58|66,66|79,80|105,105|113,129|132,133|141,141|144,144|146,147|152,167|169,169|182,182|186,186|195,198|212,212|216,216|234,239|253,260|264,265 Q:3,3|7,13|18,19|47,54|59,65|67,78|81,104|106,112|130,131|134,140|142,143|145,145|148,151|168,168|170,181|183,185|187,194|199,211|213,215|217,233|240,252|261,263|266,267 --?G---GGGEEEE????TT-------------------------??HHHHHHHH----HHTTTSS?HHHHHHHHSTTS--HHHHHHHHHHHHHHHHHHHHHHTT?SSHHHHH-----------------HH--HHHHHTT?EE?S??EEEE--------------??S?HHHHHHHHHHHH?STT?EEEEEEEE----TTTEEEEEEEEEE-TTE-EEEEETTTEEEEEETTT------HHHHHHHHHHHHH--------HTT??EE 1UKF|A PF03544.9_TonB_C_seed 109 96 !Q:2,5|12,17|34,34|43,43|46,46|54,54|60,70|72,72|74,78|80,80|90,96 Q:0,1|6,11|18,33|35,42|44,45|47,53|55,59|71,71|73,73|79,79|81,89 SS????SHHHHH??--??EEEEEEEEETTTEEEE-EEEEEESS-SS-SSHHHHH-HHHHH---????????S-S?---?S?EEEEEEEEE??---?- 2GRX|C PF03545.8_YopE_seed 8 70 !Q:14,14|30,32|57,57 Q:0,13|15,29|33,56|58,69 HHHHHHHHHHTSTT?HHHHHHHHHHHHHHH??-HHHHHHHHHHHHSEETTEEGGGGG?SSSHHHHHHTTT 1G4W|R PF03548.10_LolA_seed 39 175 !Q:2,2|15,21|41,41|45,45|66,67|72,73|77,80|88,89|91,92|103,108|120,120|124,124|134,134|137,139|150,151|162,162|165,167|173,174 Q:0,1|3,14|22,40|42,44|46,65|68,71|74,76|81,87|90,90|93,102|109,119|121,123|125,133|135,136|140,149|152,161|163,164|168,172 TS?SEEEEEEEEEEE???????EEEEEEEEEETTTEEEEEE?SSS?EEEEEESSEEEEEEGGGTEE--EEEE--GGG????SHHHHHH--H??HHHHTTEEEE------EETTEEEEEES-SSS?SEEEEEEEE?TT??-EEEEEEEETT??EEEEEEEEEE-ES???GGGGS?? 2ZPD|A PF03549.9_Tir_receptor_M_seed 3 66 !Q:0,1|43,43|65,65 Q:2,42|44,64 -?SHHHHHHHHHHHHHHHHHHTSGGGEEEEEETTTEEEEEEEE?HHHHHHHHHHTTTTTHHHHTT? 2ZWK|B PF03550.9_LolB_seed 24 197 !Q:1,2|14,19|22,22|44,44|48,48|56,57|66,66|70,70|76,76|83,83|88,91|100,110|113,114|116,118|120,122|126,126|130,130|141,141|148,149|151,155|162,162|165,165|171,176|179,187|197,197 Q:0,0|3,13|20,21|23,43|45,47|49,55|58,65|67,69|71,75|77,82|84,87|92,99|111,112|115,115|119,119|123,125|127,129|131,140|142,147|150,150|156,161|163,164|166,170|177,178|188,196 T??EEEEEEEEEEE-----?SS?EEEEEEEEEEETTTEEEEEEE?TTS?EEEEEEE--ETTEEEEE?TTS?EEEES?HHHHHH-HHHS????HHHHHHHT-----------TT??T---T???EEE?TTS?EEEEEEESSS?EEEEEE??E-----ETTSSS?EE?EEEEE-----?SS--------?EEEEEEEEE- 1IWM|A PF03551.9_PadR_seed 33 84 !Q:5,5|8,10|12,14|30,36|58,68|74,74 Q:0,4|6,7|11,11|15,29|37,57|69,73|75,83 HHHHH-HH-??B--?HHHHHHHHHHHTTTS????---HHHHHHHHHHHHHTTSEEEEE???--??????EEEEE?HHHHHHHHH 3F8C|A PF03556.10_Cullin_binding_seed 46 233 !Q:13,17|20,29|31,31|36,47|61,64|67,72|76,76|89,114|118,133|144,144|148,162|164,164|166,186|188,188|202,207|210,210|213,215|220,221 Q:0,12|18,19|30,30|32,35|48,60|65,66|73,75|77,88|115,117|134,143|145,147|163,163|165,165|187,187|189,201|208,209|211,212|216,219|222,232 HHHHHHHHHHHHH-----HT----------T-SHHH------------HHHHHHHHHHHHS---?TT-----?SSB?HHHHHHHHHHHS--------------------------TTT-?--------------TTHHHHHHHH-HHH---------------T?S?--------------------B?HHHHHHHHHHHHH?---?-TT?TT??-TTSS??HHHHHHHHHHG 3TDZ|A PF03559.9_Hexose_dehydrat_seed 79 241 !Q:0,1|15,15|17,20|25,25|29,31|34,36|40,40|44,45|52,52|54,54|65,65|69,76|86,87|89,91|114,114|117,117|125,125|130,130|134,143|152,154|156,156|158,160|170,171|178,178|187,190|192,202|204,205|208,209|223,223|228,228|230,230|240,240 Q:2,14|16,16|21,24|26,28|32,33|37,39|41,43|46,51|53,53|55,64|66,68|77,85|88,88|92,113|115,116|118,124|126,129|131,133|144,151|155,155|157,157|161,169|172,177|179,186|191,191|203,203|206,207|210,222|224,227|229,229|231,239 ??HHHHHHHHHHHHH-H????EEEE?GGG?--SS---EEE?TTT??EEETTS?S?EEEEEEEEEE?STT??-???--EEEEEEEEE??S?--EEEEEEEEEETTEEEEEEEEEE?TT?TTSEEEE?SEEE?GGG??????????TTGGGTSS??-G-G---GEEEEEEEE??TTTBSS?EEEEEEEE?--?S?---------?B??TT--EEEEEHHHHHHHH-TSTT?B?HHHHHHHHT? 4J7H|A PF03561.10_Allantoicase_seed 13 193 !Q:1,1|8,9|13,13|19,19|22,37|42,43|46,46|48,62|65,66|73,73|77,77|87,87|90,90|95,95|104,106|108,131|133,135|138,138|141,141|150,154|157,157|163,163|166,166|168,168|171,171|182,183 Q:0,0|2,7|10,12|14,18|20,21|38,41|44,45|47,47|63,64|67,72|74,76|78,86|88,89|91,94|96,103|107,107|132,132|136,137|139,140|142,149|155,156|158,162|164,165|167,167|169,170|172,181|184,192 T?EEEEES??SSB?GGGGG?SS????????????????SSEE??SS?S---------------SS?-EEEEEE?SSS?EEEEEEEEE?TT?SSSB?SEEEEEEE???S??----------------------S???TT?TT?EEEEEEEE??---TT?EEEEE?TT?S?SS?BSEEEEEEES??EESEEEEEE 1O59|A PF03562.12_MltA_seed 47 250 !Q:7,8|11,12|17,17|19,19|22,22|27,28|34,36|51,51|54,65|67,67|77,79|82,83|93,93|98,100|106,111|120,120|127,127|144,144|147,150|152,152|156,156|163,169|174,187|193,210|213,213|217,217|229,230|233,233|242,245 Q:0,6|9,10|13,16|18,18|20,21|23,26|29,33|37,50|52,53|66,66|68,76|80,81|84,92|94,97|101,105|112,119|121,126|128,143|145,146|151,151|153,155|157,162|170,173|188,192|211,212|214,216|218,228|231,232|234,241|246,249 EEEEESS??SS??EEEE?S?TT?EEEE??GGGTT???EEEEEEEETTEEEE?TT------------T?SEEEEGGGS???TT??EEEEEEETT-EEEE???HHHHH------TTTTTTSS?EEEEES?HHHHHHHHHHTEEEEE?TT----S?EEE-EEEEEE???????HHHH--------------HHHHT------------------SS?TTS?SHHHHHHHHHH?-GG-GHHHHHTT????EEEE 2G6G|A PF03566.8_Peptidase_A21_seed 5 750 !Q:0,128|131,133|137,138|148,152|164,164|173,175|177,177|181,181|184,186|201,202|205,206|209,213|215,215|224,225|239,245|259,260|262,262|270,272|275,275|288,288|293,295|298,299|303,304|306,309|325,326|330,332|340,343|348,348|350,350|353,356|360,360|362,363|369,369|374,374|381,382|384,385|387,388|390,393|396,397|400,401|406,406|411,412|415,416|419,419|424,425|428,429|445,445|448,448|455,455|458,458|462,463|469,474|486,486|495,495|499,499|504,519|523,525|529,532|541,541|544,544|559,560|562,562|567,569|573,574|582,582|585,586|591,591|595,595|597,600|602,602|606,606|619,619|633,634|637,637|643,643|646,650|665,665|673,674|702,749 Q:129,130|134,136|139,147|153,163|165,172|176,176|178,180|182,183|187,200|203,204|207,208|214,214|216,223|226,238|246,258|261,261|263,269|273,274|276,287|289,292|296,297|300,302|305,305|310,324|327,329|333,339|344,347|349,349|351,352|357,359|361,361|364,368|370,373|375,380|383,383|386,386|389,389|394,395|398,399|402,405|407,410|413,414|417,418|420,423|426,427|430,444|446,447|449,454|456,457|459,461|464,468|475,485|487,494|496,498|500,503|520,522|526,528|533,540|542,543|545,558|561,561|563,566|570,572|575,581|583,584|587,590|592,594|596,596|601,601|603,605|607,618|620,632|635,636|638,642|644,645|651,664|666,672|675,701 ???????----?????????---------------------------------------------------------------??????????????????????????????????????????????SS???GGG?-HHHHHHHHT?????HHHHHHHHHHH?TTHHHHTT???S?TTS?SS???SEEEEEEEEEEEEE??TT??SS?????S?EEEEEEEE??BSSEEEEEEEETT??--???HHHHHHHHHHHHT-?S?HHHHHHS???EE?SSSTTEEEEEEE?HHHH---TS??GGG-?S????SEEEEEEEEEEEEEE??GGG???EEEEEEE????EEEE?S?SE----EES?B??EEEEE?SSSS?EEEEET--T??S??B????SS??EE??SSSE-EEEE??SS??SS?EEEE??TT??EEEEETTTTEEEEEE?TT?EEEEEE-EE?GGG??EEEEE------EETTEEEEEEE?SSEEEEEE?EEE?SEEE------------????EEE---EEE????SHHHHGGG?TT?EEEEHHHHSEEEEE??B?SSSS???EES??SEEEEEE?TT??GGGS?SSS?S????B?SSB?EEEEEEEEEETT?EEEEEEEEEEEEE??SS?TTGGG?EE?????HHHHHHHHHHHHHS?SEEEGGG??TTHHHHHHHHHHHHHHHHHHHHHHHTT??????????????????????????????----?????????????? 3S6P|A PF03567.9_Sulfotransfer_2_seed 66 398 !Q:4,6|8,9|14,16|37,37|43,44|48,48|50,52|66,66|70,70|78,82|88,88|91,140|147,160|175,175|179,189|191,191|194,195|198,222|224,227|236,242|246,252|256,258|268,268|270,270|278,279|293,294|307,310|320,320|334,334|339,355|357,357|360,365|388,388|394,394 Q:0,3|7,7|10,13|17,36|38,42|45,47|49,49|53,65|67,69|71,77|83,87|89,90|141,146|161,174|176,178|190,190|192,193|196,197|223,223|228,235|243,245|253,255|259,267|269,269|271,277|280,292|295,306|311,319|321,333|335,338|356,356|358,359|366,387|389,393|395,397 HTTS???S??EEEE???SSSSHHHHHHHHHHHHHHHT?EEEEE??GGG?S???HHHHHHHHHHHHH?GGG?SEEEEES?????GGGGT?SS?------------------------------------------------?EEEEEE?------------?HHHHHHHHHHHHHH?BSS-----------S?SS??TT?------------------------S????HHHHHHTT?------STT------?GGG---STTHHHHHH?S?GGGGSTT?-HHHHHHHHHHHHH--TEEEEEEGGGHH----HHHHHHHHH?HHHHTTHHHHHHT?STTS----------------?S?BS??????HHHHHHHTTSHHHHHHHHHHHH-HHHHH-HHH 3F5F|A PF03571.10_Peptidase_M49_seed 27 652 !Q:3,3|11,22|25,27|33,33|35,35|37,37|41,41|43,43|47,57|60,61|70,70|78,81|92,92|95,96|98,102|110,110|113,120|122,125|130,130|133,133|141,142|168,168|188,188|203,203|205,205|216,216|223,223|225,225|234,235|259,259|262,271|274,274|277,283|294,296|302,304|312,313|327,328|331,333|336,336|340,340|369,373|376,376|380,380|384,384|388,389|391,391|398,405|407,407|410,411|438,438|440,441|449,450|453,458|477,477|489,492|496,496|512,513|515,515|526,527|530,530|540,540|545,545|568,568|581,585|589,589|600,601|603,607|611,612|619,626|631,631|634,636|650,650 Q:0,2|4,10|23,24|28,32|34,34|36,36|38,40|42,42|44,46|58,59|62,69|71,77|82,91|93,94|97,97|103,109|111,112|121,121|126,129|131,132|134,140|143,167|169,187|189,202|204,204|206,215|217,222|224,224|226,233|236,258|260,261|272,273|275,276|284,293|297,301|305,311|314,326|329,330|334,335|337,339|341,368|374,375|377,379|381,383|385,387|390,390|392,397|406,406|408,409|412,437|439,439|442,448|451,452|459,476|478,488|493,495|497,511|514,514|516,525|528,529|531,539|541,544|546,567|569,580|586,588|590,599|602,602|608,610|613,618|627,630|632,633|637,649|651,651 HHH-HHHHHHH------------HH???GGGSB-B?S-GGG?B?SSB?----------TT??HHHHHHHH-HHHHHTT?--?STTEEEEEEE?TT??E-----EEEEEEE?SS????????T----TGGG?SE-EEETTEE--EEEEEEETHHHHHHHHHHHHHHHTT?SSHHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHS?S?SEEEEEEEEE?SSSTTS?S?EEEEEEEE??HHHHHHHHHHHHTHHHHHHTSSS?GG----------GS?SS???????EEEEEEEESS???SEEEE???HHHHHHT??EEEEEHHHHTTSS??SG---GG?TTB?HHHHHHHHHHHHHHHHHHHHHHHHTTTT?????BB?TTS?BSS?TTT-?B?TTTSSB-?---???B?TT??HHHHSTTTHHHHHHHHHHHHHHHHTT?H--HHHHHHT??HH------HHHHHHHHHHHHHHHHHH-HGGGGEEGGGT----EES?HHHHHHHHHHHHHHH--T?TTSEEEEEEE-?TT-SSEEEEEEE?GGGT-TTTHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHT?????TTT?HHHHHHHHHH--T?????EEE??EEEEET--------TEEE-EE???SSHHHHHHHHHTT?T 3T6B|A PF03572.13_Peptidase_S41_seed 142 296 !Q:7,11|14,24|40,45|48,48|55,55|58,69|81,89|98,102|109,159|163,165|167,168|170,187|191,191|197,197|200,201|209,209|218,220|226,232|240,244|247,258|260,260|264,266|274,274|278,278|280,280|285,291|295,296 Q:0,6|12,13|25,39|46,47|49,54|56,57|70,80|90,97|103,108|160,162|166,166|169,169|188,190|192,196|198,199|202,208|210,217|221,225|233,239|245,246|259,259|261,263|267,273|275,277|279,279|281,284|292,294 EEEEEEE???--ST-----------THHHHHHHHHHHHHH------TT?SEEEEE?TT??-------???HHHHHHHHHHH??-------SSEEEEEE----?SSSEEE---------------------------------------------------EEE?-?S??S?-----------------SSS?EEEEE?TT??THHHHHH-HHHHHTTS?--EEEES?-?????EEEEEEE?----TT------------S?EEE---EEEEEEE?TTS?B-STTT---????SEE?- 1K32|A PF03573.8_OprD_seed 47 523 !Q:0,1|6,8|22,47|50,51|61,66|86,128|137,137|153,153|155,157|164,165|170,171|181,181|198,204|206,206|208,208|211,212|218,224|226,226|228,228|238,238|240,240|269,269|273,273|287,287|290,314|317,321|335,335|352,355|358,371|373,373|376,381|384,385|388,391|395,395|411,416|430,433|435,462|474,475|482,482|496,505|507,508|522,522 Q:2,5|9,21|48,49|52,60|67,85|129,136|138,152|154,154|158,163|166,169|172,180|182,197|205,205|207,207|209,210|213,217|225,225|227,227|229,237|239,239|241,268|270,272|274,286|288,289|315,316|322,334|336,351|356,357|372,372|374,375|382,383|386,387|392,394|396,410|417,429|434,434|463,473|476,481|483,495|506,506|509,521 ??TTTT???EEEEEEEEEEEEE??-------????-----------??EE--EEEEEEEEE??????SSSEEEEEEEEEEEEEEEE?????--??-???-------??------??-??----??--??EEEEEEEE-EEEEEETTEEEEEEE-E???BTTBEE??SSSS??EEEEEEEEE?SSTTEEEEEEEEEEEE???????E-E?BB??GGGSS----???B?S?EEEEEEEEE?S-SSEEEEEEEEEETTTEEEEEEEEEEEEE?SSS-EEEEEEEEEEEEE?TT----?--------------------TT?--??EEEEEEEEEEEEE-TTEEEEEEEEEEESSS????BT--------------T-EE-???--TT??SS????STT?EEEEEEEEEEGGGGT?-----TTEEEEEEEEEEE????S??-------------------?????--EEEEEEEEEEE??SSTTTT?EEEEEEEEEEESS----------S??EEEEEEEEEEEEE? 3T0S|A PF03574.10_Peptidase_S48_seed 4 149 !Q:6,6|16,17|35,38|40,42|46,46|62,63|67,67|70,70|72,72|75,75|87,87|89,91|94,95|117,117|121,125|143,143|147,147 Q:0,5|7,15|18,34|39,39|43,45|47,61|64,66|68,69|71,71|73,74|76,86|88,88|92,93|96,116|118,120|126,142|144,146|148,148 HHHTTT?HHHHHHHTT??HHHHHHHHHHHHHHHTT????S???SSS?HHHHTHHHHHHHHSB??TTS?SS?S?SS?HHHHHHHHTTS?S???SB??EEHHHHHHHHHHHHHHHHTTS?STT?????HHHHHHHHHHHHHHTSS?EEE?T 4J01|A PF03575.12_Peptidase_S51_seed 24 208 !Q:11,11|14,20|22,22|31,39|47,47|53,54|56,56|69,69|78,78|82,83|93,98|101,105|107,107|114,117|119,121|123,128|130,130|132,134|136,146|153,154|156,175|190,190|195,196|199,199|204,204|207,207 Q:0,10|12,13|21,21|23,30|40,46|48,52|55,55|57,68|70,77|79,81|84,92|99,100|106,106|108,113|118,118|122,122|129,129|131,131|135,135|147,152|155,155|176,189|191,194|197,198|200,203|205,206 HHHHHHHHHGG-GT------?E-EEETTSSS--------?HHHHHHH?SEEEE??S?HHHHHHHHHHTT?HHHHHHHH-HTT-?EEEEETHHH------HH-----T-SSBSTT??--S???S----??S?S---B-?------???SSSEEE-?S?---????????-???---?HHHHHHHHHHHSTT?EEEE??TT?EEEE?SS? 1R9G|A PF03576.9_Peptidase_S58_seed 108 494 !Q:1,1|9,9|17,17|20,33|36,36|42,43|57,57|73,73|75,77|87,87|90,90|92,94|106,106|119,121|123,126|133,137|143,144|149,149|153,166|177,197|201,210|219,219|226,226|238,242|244,244|246,248|259,263|265,269|272,273|275,275|279,279|282,282|290,368|376,376|378,380|400,405|408,408|425,426|428,428|431,440|444,445|449,451|473,476|479,482|484,485|488,488|491,493 Q:0,0|2,8|10,16|18,19|34,35|37,41|44,56|58,72|74,74|78,86|88,89|91,91|95,105|107,118|122,122|127,132|138,142|145,148|150,152|167,176|198,200|211,218|220,225|227,237|243,243|245,245|249,258|264,264|270,271|274,274|276,278|280,281|283,289|369,375|377,377|381,399|406,407|409,424|427,427|429,430|441,443|446,448|452,472|477,478|483,483|486,487|489,490 S?SGGGSTT?EEEEEEE-EE?------------?SS?BTTTB-?EEEEEEEEESSSS?TTTEEEEEEEEEEEE?S?-?BSHHHHHHH?EE?S--?EEEEEGGGHHH-HHHHHHHHHHHH--?T----TBTTTB?????EEEEE??TTTS?GGG????----------HHHHHHHHHH-?-------------------BSS-------???BSSGGGTT?EETTEE?EEEEEEEEEES-----S-S?--EEEEEEEEEE??-??G-----GG??B-TTB?HH-HHTTTSS??----------------------------------------------------------------------???????EEEEEEE?S???HHHHHHHHHHHHHHHHHTT--????TT?EEEEEEEEEEEEEETT??S?EE----------EEE??GGG--?HHHHHHHHHHHHHHHHHHHHS???-EE?---G--GG?EE??? 3N5I|A PF03583.9_LIP_seed 12 308 !Q:1,2|8,9|12,14|28,28|34,34|41,46|49,49|55,55|71,75|78,78|103,103|107,108|110,110|119,121|150,150|162,162|175,176|184,184|187,188|190,193|197,197|200,200|208,208|219,220|224,224|227,229|240,240|244,244|260,261|271,279|302,305 Q:0,0|3,7|10,11|15,27|29,33|35,40|47,48|50,54|56,70|76,77|79,102|104,106|109,109|111,118|122,149|151,161|163,174|177,183|185,186|189,189|194,196|198,199|201,207|209,218|221,223|225,226|230,239|241,243|245,259|262,270|280,301|306,307 S??TTGGG--GS---THHHHHHHHHHTT?EEEEE?TTTTTT-----?TT?HHHHH-HHHHHHHHHHHHHTT---??TT?EEEEEEETHHHHHHHHHHHHHHHH?TTS--E-EEEEEEES???BHHHHHHHHTTSTTHHHHHHHHHHHHHH?HHHHHHHHTTB?HHHHHHHHHSTT??HHHHHHH?TT??G----GGG-BS?TTGGGST-THHHHHHHSB??TTT?SS???SEEEEEEETT?SSS?HHHHHHHHHHHHHTT-?EEEEEEESS??-------HHHHHHHTHHHHHHHHHHHHHT????TT 2VEO|A PF03587.9_EMG1_seed 60 442 !Q:6,8|11,35|38,39|43,43|48,49|53,55|57,85|89,90|109,109|112,112|115,115|120,121|126,126|131,131|134,137|153,156|162,168|175,176|178,178|182,182|185,185|187,189|196,197|199,199|203,203|205,253|260,376|379,379|382,383|387,387|392,392|396,397|405,405|407,411|413,418|422,423|426,428 Q:0,5|9,10|36,37|40,42|44,47|50,52|56,56|86,88|91,108|110,111|113,114|116,119|122,125|127,130|132,133|138,152|157,161|169,174|177,177|179,181|183,184|186,186|190,195|198,198|200,202|204,204|254,259|377,378|380,381|384,386|388,391|393,395|398,404|406,406|412,412|419,421|424,425|429,441 EEEEEE???EE??-??????------------????EE??TTT?HHHH--HHT---T?---------------------------?GGG??HHHHHHHHHHHHHSHHHH-TT?EE-EEEE--ETTS?EEEE?TT????SSHHHHHHHHHHHHH----HSEEE??-????EEEEEE?-S?GGG-TS?S---SEEEEE--E?TTS?B?-----------------------------------------------?HHHHHH---------------------------------------------------------------------------------------------------------------------TS?TT-?EEE-EEEE?SSS??TTTTTTT?S----?E------EBS?-SS???HHHHHHHHHHHHH 3BBH|A PF03588.9_Leu_Phe_trans_seed 9 184 !Q:0,0|12,12|15,17|19,20|23,24|28,29|36,36|39,39|41,44|54,56|63,63|74,80|85,85|100,101|114,118|161,162|169,170|178,178|182,182 Q:1,11|13,14|18,18|21,22|25,27|30,35|37,38|40,40|45,53|57,62|64,73|81,84|86,99|102,113|119,160|163,168|171,177|179,181|183,183 ?HHHHHHHHHTT?EE???T--TS??EEE??SSEEEE?GG-G????HHHHHHHHT???EEEESS?HHHHHHHHHT??---??GGGS?HHHHHHHHHHHHTT--SEEEEEEEETTE-----EEEEEEEEEETTEEEEEEEEESSTTHHHHHHHHHHHHHHHTT??EEEEES??HHHHHTT?EEE?H 2Z3N|A PF03589.8_Antiterm_seed 21 104 !Q:1,3|8,8|15,22|26,26|34,34|37,38|42,42|48,49|51,51|69,70|74,74|103,103 Q:0,0|4,7|9,14|23,25|27,33|35,36|39,41|43,47|50,50|52,68|71,73|75,102 S---TTSB?TTTTTS?-------EEE?HHHHHHH-TS??EEE?TTTTT??B?STTHHHHHHHHHHHSTT??HHH-HHHHTHHHHHHHHHHHHHHHHHHHHHHT? 4MO1|A PF03590.10_AsnA_seed 6 246 !Q:0,1|6,6|26,26|30,33|42,42|44,45|50,53|56,57|63,64|68,68|70,71|84,85|88,88|98,98|101,101|103,105|108,109|121,122|125,126|154,159|161,161|164,164|180,180|199,200|203,204|208,209|212,214|219,220|224,224|230,230|246,246 Q:2,5|7,25|27,29|34,41|43,43|46,49|54,55|58,62|65,67|69,69|72,83|86,87|89,97|99,100|102,102|106,107|110,120|123,124|127,153|160,160|162,163|165,179|181,198|201,202|205,207|210,211|215,218|221,223|225,229|231,245 ??HHHH-HHHHHHHHHHHHHHHHHHH?EEE????SEEETTSS?S??TTTT????EE??SSSTT??EEE?S??TTHHHHHHHHTT??TT?EEEEEEEEE?TT?S???SS??SEEEEEEEEEE??TT??SHHHHHHHHHHHHHHHHHHHHHHHHHS-?????S?SS?EEEEHHHHHHHSSSS?HHHHHHHHHHHHSEEEEE??SS??SSS??SS???TTTB??SSB?TTSSB?SEEEEEEEETTTTEE- 12AS|A PF03592.11_Terminase_2_seed 71 229 !Q:0,83|98,99|110,156|164,164|167,168|179,179|186,194|198,207|214,214|221,228 Q:84,97|100,109|157,163|165,166|169,178|180,185|195,197|208,213|215,220 ??????????????----??-??????????-??-----????---?????---????????????????---???????????HHHHHHHHHHHHTT??EEEEEEEEET-----------------------------------------------TEEEEEE-EE??HHHHHHHHHH-HHHHTT-----?--?EEE----------EEEEEE-EEEEEE?????--? 3ZQO|A PF03595.12_SLAC1_seed 159 595 !Q:0,3|18,20|23,30|33,48|54,56|58,64|85,86|91,91|95,97|102,103|106,107|113,121|123,126|143,143|154,191|205,205|217,234|239,242|245,248|250,250|254,257|261,263|275,279|285,305|328,328|336,339|342,352|377,426|428,430|455,472|476,507|522,524|531,539|542,547|557,575|595,595 Q:4,17|21,22|31,32|49,53|57,57|65,84|87,90|92,94|98,101|104,105|108,112|122,122|127,142|144,153|192,204|206,216|235,238|243,244|249,249|251,253|258,260|264,274|280,284|306,327|329,335|340,341|353,376|427,427|431,454|473,475|508,521|525,530|540,541|548,556|576,594 ????GGGGHHHHHHHHHH---HH--------HH----------------TTTTT---S-------TTHHHHHHHHHHHHHHHHHH--HHHH-HHH---HHHH?-HH--HHHHH---------H----HSTTGGGGGGHHHHHH-HHHHHHHTTT-------------------------------------?HHHHHHHHHHHHH-HHHHHHHHHTG------------------GGGG-?--SS----S?GGG--??GGG---HHHHTHHHHHH???--TTTTT--------------------?HHHHHHHHHHHHHHHHHHHHHH-HHHHHHS?-??GG-----------GGGGGGGGGHHHHHHHHHHHHHTT--------------------------------------------------T???HHHHHHHHHHHHHHHHHHHTHHHH------------------TTT----------------------------??-?GGGGGGHHHHHHHH---HHHHHH---------HH------TTSSHHHHH-------------------HHHHHHHHHHHHHHHHHHH- 3M72|A PF03598.10_CdhC_seed 22 434 !Q:0,3|6,6|14,17|30,30|32,36|42,43|47,49|52,56|58,59|64,65|69,69|71,74|81,81|84,85|115,115|128,130|146,146|150,151|157,160|165,170|175,175|192,193|197,197|204,204|210,210|213,214|222,223|227,229|240,240|245,246|250,251|275,280|283,283|288,292|294,295|315,316|318,319|323,324|333,333|336,338|345,345|367,368|389,389|398,398|402,402|417,417|423,433 Q:4,5|7,13|18,29|31,31|37,41|44,46|50,51|57,57|60,63|66,68|70,70|75,80|82,83|86,114|116,127|131,145|147,149|152,156|161,164|171,174|176,191|194,196|198,203|205,209|211,212|215,221|224,226|230,239|241,244|247,249|252,274|281,282|284,287|293,293|296,314|317,317|320,322|325,332|334,335|339,344|346,366|369,388|390,397|399,401|403,416|418,422 ????SS?BSGGGTT????TTTEEEEEETTT-S--???EEEEE??STT-??TT?????S??SSSS?-TTE-E????EEEEEE?TT??GGGHHHHHTHHHHHHTTBTTEEEESSSTT?EEEEEHHHHHHT??-GGGHHHHHHHHHHHS?TTT??EEEEE????HHHH------HHTT-TTTHHHHHHHHHHHHH??STT?SEEEEE?GGGGT?TT??EEEBTTB??TTS???HHHHHHHHHH?TTSS??EEE??SEEETTTTEEHHHHHHHHHHTTT??????TT?SSSS?????S??SEEEEEETTTTEEEEEETT??S??TTS??HHHHHHHH?SS???TTEEEE?GGGGGSTTTTGGGTGGGGEEE??HHHHHHTHHHHHHHHHHTTS?TTGGGGSB?TTT?SSHHHHHHHHHHTT?GGGGS-------???? 1MJG|M PF03599.11_CdhD_seed 9 443 !Q:3,3|6,12|16,17|21,24|28,31|35,37|39,40|51,51|65,66|69,75|82,84|90,91|96,102|116,117|124,124|126,130|146,147|153,153|156,156|170,171|175,175|177,178|194,194|197,201|206,209|212,216|234,235|239,239|241,241|246,248|255,264|271,281|287,287|293,296|313,313|317,318|320,321|324,324|330,331|334,335|357,357|359,359|366,366|370,371|380,380|382,382|399,400|404,405|409,410|427,427|431,432 Q:0,2|4,5|13,15|18,20|25,27|32,34|38,38|41,50|52,64|67,68|76,81|85,89|92,95|103,115|118,123|125,125|131,145|148,152|154,155|157,169|172,174|176,176|179,193|195,196|202,205|210,211|217,233|236,238|240,240|242,245|249,254|265,270|282,286|288,292|297,312|314,316|319,319|322,323|325,329|332,333|336,356|358,358|360,365|367,369|372,379|381,381|383,398|401,403|406,408|411,426|428,430|433,442 EEE?SS-------STT??EEE????SST----TTS???S??EEEEEEESSS?HHHHHHHHHHHTT??EE-------ETTEEE???EEEEE??SSST-------HHHHHHHHHHHHH??SEEEEE?S-----SHHHHHHHHTTTTTS??EEEEE?TT-THHHHHHHHHHTT??EEE-E?-SHHHHHHHHHHHHHH-TT?--??EEEE????SH-----HHHHHHHHHHHHHHHHS??TTS?S?BEEE???SSHHHH----------HHHHHH-----------HHHTT?SEEEE????HHHHHHHHHHHHHHTS?SSS??B??SS?EEETT??SS??EEEEESBHHHHHHHHHHHHHH?S?EEEEEE?SSS??HHHHHHHT?S?HHHHHHHHHHHTHHHH--SSS??EEE-?GGGGGGHHHHHHHHTS?EEE??SSGGGHHHHH 4DJF|C PF03600.11_CitMHS_seed 32 647 !Q:11,12|17,17|20,20|36,51|55,55|57,70|79,79|114,114|135,135|145,145|153,153|155,157|181,181|188,192|195,195|199,200|202,204|217,218|224,226|236,425|452,454|459,486|491,509|523,523|530,538|541,541|577,584|603,607|611,611|633,634 Q:0,10|13,16|18,19|21,35|52,54|56,56|71,78|80,113|115,134|136,144|146,152|154,154|158,180|182,187|193,194|196,198|201,201|205,216|219,223|227,235|426,451|455,458|487,490|510,522|524,529|539,540|542,576|585,602|608,610|612,632|635,646 HHHHHHHHHHH--HHHH?SS?HHHHHHHHHHHTTTT----------------SSS?H--------------HHHHTTTT?HHHHHHHHHHHHHHHHHHTTHHHHHHHHHHSTTS?STHHHHHHHHHHHHHHHTTS?HHHHHHHHH-HHHHHHS?S???SSTTTHHHHHHHHHHHTSSSSSS?HHHHHH-----HH-HHT??H---HHHHHHHHHHHH--HHHHH---HHHHHHHHS?????????????---------------------------------------------------------????------------------------------------------------------------------------------------------------------------------??STHHHHHHHHHHHHHHHHHHHHHHHH???SSHH----------------------------HHHH-------------------HHHHHHHHHTTSS?HHHHHH---------HS?HHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHH--------TTTTHHHHHHHHTTSSSS-----SSS?THHHHHHHHHHHHHHHHHHTT??THHHHHHHHHHH 4F35|A PF03602.10_Cons_hypoth95_seed 27 207 !Q:2,3|10,17|21,33|47,52|56,56|63,63|66,66|77,77|84,84|86,86|92,92|103,104|106,109|116,116|118,118|126,127|130,131|138,140|144,144|147,148|160,160|163,166|179,179|181,186 Q:0,1|4,9|18,20|34,46|53,55|57,62|64,65|67,76|78,83|85,85|87,91|93,102|105,105|110,115|117,117|119,125|128,129|132,137|141,143|145,146|149,159|161,162|167,178|180,180|187,206 EE??SSTTTT-------?EEE????-????????HHHHHHHHHHHHH------HTT?EEEETT?TT?HHHHHHHHTT?SEEEEE?S?HHHHH-HHHHHHHHTT??T----TTEEEE?S?HHHHTTS??SS??EEEEEE???SSS?HH--HHHHHHHHHTT?EE----EEEEEEEEEESS-S????-?TTEEEEEEEEETTEEEEEEE 1VQ1|A PF03603.8_DNA_III_psi_seed 26 154 !Q:0,37|40,41|46,46|49,51|54,54|56,56|67,68|76,76|84,84|87,87|89,91|97,98|100,101|103,104|107,118|121,128|131,132|139,139 Q:38,39|42,45|47,48|52,53|55,55|57,66|69,75|77,83|85,86|88,88|92,96|99,99|102,102|105,106|119,120|129,130|133,138|140,153 ??????????????????????????--?--???????TT??EEEE?SS???TT?H-HHHHHHHHHT??GGGEEEE?HHHHTTS?TT?B-??EEEES??S??S-?BS-----------?EE--------EE??HHHHHH?HHHHHHHHHHHHHT 1EM8|B PF03604.8_DNA_RNApol_7kD_seed 22 36 !Q:0,0|2,2|4,6|9,10|12,16|20,23|27,31|33,35 Q:1,1|3,3|7,8|11,11|17,19|24,26|32,32 ?B?S---SS??B??-??SSS????SSS?????B??? 1K83|L PF03607.12_DCX_seed 53 71 !Q:3,3|5,5|8,8|23,24|28,28|30,30|33,34|47,47|52,54|63,63|67,70 Q:0,2|4,4|6,7|9,22|25,27|29,29|31,32|35,46|48,51|55,62|64,66 EEE?T-TT?SSHHHHHHHHHHHH??SSS?S-SS-?SEEEESSSSSEE?SGGG-??TTEEEEEE-SSS-??? 2DNF|A PF03610.11_EIIA-man_seed 36 129 !Q:5,5|8,8|23,27|34,34|36,36|39,42|55,55|59,60|63,63|86,86|89,90|93,95|100,101|113,114|117,119 Q:0,4|6,7|9,22|28,33|35,35|37,38|43,54|56,58|61,62|64,85|87,88|91,92|96,99|102,112|115,116|120,128 EEEEE?SB-THHHHHHHHHHHHH??--?SSEEEE?B?TT--??HHHHHHHHHHHH-TTS??TT?EEEEESSTTSHHHHHHHHHHTT?TT--EE---EEES??HHHHHHHHHHH--TT???HHHHHHHHH 3MTQ|A PF03615.10_GCM_seed 6 145 !Q:0,5|8,9|12,12|15,16|20,20|27,28|31,31|36,37|39,39|42,42|48,49|56,59|63,65|68,70|84,84|87,88|90,92|98,100|106,107|114,114|124,127|129,134|144,145 Q:6,7|10,11|13,14|17,19|21,26|29,30|32,35|38,38|40,41|43,47|50,55|60,62|66,67|71,83|85,86|89,89|93,97|101,105|108,113|115,123|128,128|135,143 ??????SS??SS?EE??BTT?HHHHTT??SS?EEEE??S?TT?EEEEE??EEEETT????SSS???EE???SSHHHHHHHHHSB?SS--S?-?BEEEE???TBTTB??EEEEEE?SSBEEEEEE????S????-?HHHHHHHHS?- 1ODH|A PF03621.8_MbtH_seed 87 72 !Q:0,4|6,8|10,12|14,18|27,27|29,29|37,39|47,51|53,61 Q:5,5|9,9|13,13|19,26|28,28|30,36|40,46|52,52|62,71 ??---S???S???S----?EEEEEETT?S?EEEETTS???SSEEEEE---?-S?-------?HHHHHHHHHH 4GR4|A PF03623.8_Focal_AT_seed 7 140 !Q:0,5|8,8|30,32|62,62|134,139 Q:6,7|9,29|33,61|63,133 ??????TT?HHHHHHHHHHHHHHHHHHHHS???GGGGHHHHHHHHHHHHHHHHHHHTTGGGS?GGGHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTSTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT???-?? 1OW6|A PF03625.9_DUF302_seed 170 82 !Q:12,27|35,35|46,47|54,54|57,57|64,69|79,80 Q:0,11|28,34|36,45|48,53|55,56|58,63|70,78|81,81 EEEHHHHHHHHH???----------???EEEEEEE?HHHHHHHHHH?-GGGGGG?SE-EEEEEE------ETTEEEEEE??H 1J3M|A PF03627.8_PapG_N_seed 4 231 !Q:0,23|32,33|43,43|47,48|53,56|63,64|69,69|71,71|75,75|78,79|96,96|100,100|109,109|112,112|116,116|119,119|136,138|143,144|147,147|152,157|164,165|168,169|193,198|206,208|218,230 Q:24,31|34,42|44,46|49,52|57,62|65,68|70,70|72,74|76,77|80,95|97,99|101,108|110,111|113,115|117,118|120,135|139,142|145,146|148,151|158,163|166,167|170,192|199,205|209,217 -----------------------?EEEEEEEE??EEEEEEEEE?TTS??EEEE????EEEEEE--EEEE?S?SEE?SS??EEEEEEEEEEEESEEE?TTS?EEEEEEEE?TT?EEE?TT?SSEEEEEEEEEEEEEE???EESS??TT?EEEE??????EEEEEE??TT??SEEEEEEEEEEEEEEEEEESSTT??????HHHHTTS???EEEEEEEEE???---------- 1J8R|A PF03628.8_PapG_C_seed 3 109 !Q:0,1|3,4|8,8|11,11|24,24|36,37|40,41|45,45|63,63|86,87|89,94|96,97|107,108 Q:2,2|5,7|9,10|12,23|25,35|38,39|42,44|46,62|64,85|88,88|95,95|98,106 ??S??SSS?TT?EEEEEEEEEESS?EEEEEEEEESS??SS??TTS?EEEEETTEEEEEEETTB?SSEEEEEESSSEEEEEEEEEEE??S??????S??EEEEEEEEE?? 2WMP|B PF03629.13_DUF303_seed 136 707 !Q:13,35|38,38|42,42|46,47|51,55|59,65|72,103|107,121|125,126|128,129|132,133|142,165|167,167|182,182|185,186|192,195|198,199|202,206|213,443|460,471|473,473|482,483|488,491|496,510|531,538|540,547|549,550|552,555|561,561|563,576|581,607|609,614|620,621|624,632|639,653|655,655|658,661|663,666|668,668|674,686|688,688 Q:0,12|36,37|39,41|43,45|48,50|56,58|66,71|104,106|122,124|127,127|130,131|134,141|166,166|168,181|183,184|187,191|196,197|200,201|207,212|444,459|472,472|474,481|484,487|492,495|511,530|539,539|548,548|551,551|556,560|562,562|577,580|608,608|615,619|622,623|633,638|654,654|656,657|662,662|667,667|669,673|687,687|689,706 SEEEEEEESHHHH---------------------??BT-EEE?TTT??EEE?????GGG?---??-TTEEEE-------------------------------?TTS--------------?EEE??S--ST--TTTTSTTS??---------------------?B?SHHHHHHHHHHHHT?TT??EEEEE-???TT??GG-----GGSTTS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHHHHHHHHHHHHGGG------------S?EEEEEEEE??GGGS----SSHH---------------HHHHHHHHHHHHHHHHHHHT--------T-------?T--T??--EEEEE?S-----------???TTHH---------------------------H------HHHHH--HH?-??-----TTEEEE---------------E?TT----S?---B?TTSSS-------------B?HHHHHHHHHHHHHHHHHH 3PT5|A PF03630.9_Fumble_seed 11 402 !Q:0,0|7,7|20,22|30,30|43,43|53,53|57,57|90,102|109,109|131,134|139,140|156,156|161,161|171,171|174,175|177,178|184,190|220,220|234,236|248,249|264,266|273,273|286,290|296,315|318,319|348,350|361,361|380,382|390,390 Q:1,6|8,19|23,29|31,42|44,52|54,56|58,89|103,108|110,130|135,138|141,155|157,160|162,170|172,173|176,176|179,183|191,219|221,233|237,247|250,263|267,272|274,285|291,295|316,317|320,347|351,360|362,379|383,389|391,401 ?EEEEEE?SSEEEEEEEEES???HHHHHHS?HHHHHHHHHHHH?SEETTTEEE?GGG?EEEEEETTEEEEEEEEEEEGGGHHHHHHHHHH-------------TTGGGT?SEEEEESTTHHHHHHHHHHHH??--EEEE??HHHHHHHHHHHHHHH?BTTB?SEEEEESTT?TT--T-?EEEEE?-?????SEEEEEESSSEEEEEEEETTEEEEEEEES?SHHHHHHHHHHHH???SHHHHHHHHHH??GGGTSEEHHHHHSS?--BGGGTB?TTSEEETTGGGG-----SHHHH--------------------HH??HHHHHHHHHHHHHHHHHHHHHHHHHHHT???EEEESGGGTS?THHHHHHHHHHHHHTTTS???BEETTTT?HHHHHHHHHTT 2EWS|A PF03632.10_Glyco_hydro_65m_seed 16 521 !Q:4,9|16,17|19,25|27,31|34,48|54,55|57,61|63,63|67,67|83,83|103,112|120,122|124,127|133,135|139,153|156,157|160,160|163,163|174,174|183,187|209,209|220,221|224,225|231,239|243,244|266,266|269,274|280,282|293,295|300,302|310,316|318,318|327,330|334,336|338,338|342,344|351,351|360,360|364,364|373,384|390,390|398,401|410,412|414,414|430,430|432,434|442,442|448,464|468,468|474,475|479,482|499,503|507,516 Q:0,3|10,15|18,18|26,26|32,33|49,53|56,56|62,62|64,66|68,82|84,102|113,119|123,123|128,132|136,138|154,155|158,159|161,162|164,173|175,182|188,208|210,219|222,223|226,230|240,242|245,265|267,268|275,279|283,292|296,299|303,309|317,317|319,326|331,333|337,337|339,341|345,350|352,359|361,363|365,372|385,389|391,397|402,409|413,413|415,429|431,431|435,441|443,447|465,467|469,473|476,478|483,498|504,506|517,520 HHHH------HHHHHH??S-------S?----TT??-----------??TTTTS??T-----T?SSB?THHHHTHHHHHHHHS?HHHHHHHHHHHHTTHHHHH----------HHHHTTT??-S????SSBSS---SSB??----------?-?HH--HH-TT?THHHHHHHHH-HHHHHHHH?--??TTTTTHHHHHHHHHHHHHHHH?EEETTTTEEE??SB??SSTTS--------?SBS??HHHHHHHHHHHHHHHHHHTTS?HH------HHHHH???HHHHHHHHHH---HHTB???EETTTTE-------E?SSTTGGGS????GGG---S?GGG?--SGGGTS?HHHHHHSS?BSS?SHHHHHHH------------TTTSS?HHHHHHH----HHHHGGGB???S-TTHHHHHHHHHHHTT?H---HHHHHHH-TTTTT-----------------TTT-TTTTS?-GGG??-?GGGGGHHHHHHHTTTS??---EEE----------TTEE 1H54|A PF03633.10_Glyco_hydro_65C_seed 18 58 !Q:0,3|6,6|9,9|14,14|22,22|41,43|56,57 Q:4,5|7,8|10,13|15,21|23,40|44,55 ????TT?SE-EEEE-EEETTEE-EEEEEETTEEEEEEEESS--?EEEEETTEEEEE?? 1H54|A PF03635.12_Vps35_seed 23 1610 !Q:0,1123|1139,1142|1144,1144|1147,1155|1174,1174|1191,1199|1210,1298|1301,1301|1318,1319|1329,1334|1352,1366|1387,1408|1410,1412|1428,1428|1431,1437|1455,1455|1475,1475|1477,1485|1487,1528|1533,1533|1535,1537|1556,1564|1584,1586|1590,1590|1594,1594 Q:1124,1138|1143,1143|1145,1146|1156,1173|1175,1190|1200,1209|1299,1300|1302,1317|1320,1328|1335,1351|1367,1386|1409,1409|1413,1427|1429,1430|1438,1454|1456,1474|1476,1476|1486,1486|1529,1532|1534,1534|1538,1555|1565,1583|1587,1589|1591,1593|1595,1609 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?TTTTHHHHHHHHHHH----T-TS--------?HHHHHHHHHHHHHHHHTT?SSSHHHHHHHHHHHHH---------HHHHHHHTTT-----------------------------------------------------------------------------------------TT?SSHHHHHHHHHHHHHH--HHHHHHHTT?----?HHHHHHHHHHHHHHHHH?-------------?TTHHHHHHHHHHHHHHHHHH----------------------H???HHHHHHHHHHHHHHH-TT?????--HHHHHHHHHHHHHHHHT?SSHHHHHHHHHHTHHHHHT?B?--------T------------------------------------------TTTT?B???HHHHHHHHHHHHHHHHHS??-------HHHHHHHHHHHHHHHHHHH---TTT?TTS?HHHHHHHHHHHHTTT 2R17|C PF03636.10_Glyco_hydro_65N_seed 14 347 !Q:5,7|11,11|15,15|21,21|24,24|30,46|49,51|53,66|68,71|74,75|79,90|95,107|110,111|114,115|121,126|128,132|134,134|141,143|147,149|177,177|180,180|190,190|205,208|210,210|212,212|215,215|217,217|222,223|227,231|234,242|249,256|259,259|263,263|271,275|277,282|284,288|302,303|306,311|318,318|325,325|328,328|334,334|342,342|346,347 Q:0,4|8,10|12,14|16,20|22,23|25,29|47,48|52,52|67,67|72,73|76,78|91,94|108,109|112,113|116,120|127,127|133,133|135,140|144,146|150,176|178,179|181,189|191,204|209,209|211,211|213,214|216,216|218,221|224,226|232,233|243,248|257,258|260,262|264,270|276,276|283,283|289,301|304,305|312,317|319,324|326,327|329,333|335,341|343,345 EEEES???GGG-HHH-HHHHT?EE?SSEEE?--------??-----?TT???S--------------S????EE--ETT??----------EEEE??----------?SS??TT??SEEEE???-??B?????E-EETTEE-??TTT---SEEEEEEEEEETTTTEEEEEEEEEETT-EE-EEEEEEEEE?SSSTTEEEEEEEEE----E?S-SS?E-EEEE??EEE?????TT--???????EEEEEE--------EE?SSE-EEEEEEE--???S------S?????EEEEEEEEEESSE--EE???-??BTTEEE?EEEEEE?TT?EEEEE-EEEEEEE-TTS?- 1H54|A PF03637.12_Mob1_phocein_seed 12 181 !Q:0,6|9,13|20,21|24,25|53,53|57,57|66,66|69,69|71,72|76,77|79,80|82,84|102,102|107,107|113,115|121,121|150,150|170,170|172,172 Q:7,8|14,19|22,23|26,52|54,56|58,65|67,68|70,70|73,75|78,78|81,81|85,101|103,106|108,112|116,120|122,149|151,169|171,171|173,180 ----???TT??--?HHHHTS??TT??HHHHHHHHHHHHHHHHHHHHHHTGGGS?TTT?SSEESSTT?EE?B??SSS??S-?B???HHHHHHHHHHHHHHHHT?TTTS?SSTTS???TTHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHT?S?GGGGGGGH 1PI1|A PF03639.8_Glyco_hydro_81_seed 5 726 !Q:1,2|5,6|9,12|14,14|17,18|22,26|37,38|42,42|44,45|48,48|58,59|65,66|68,69|71,71|75,78|82,83|87,91|104,105|148,148|151,151|156,157|160,160|169,172|174,175|187,187|194,194|197,201|203,203|219,219|225,225|230,231|234,238|250,251|261,265|267,267|271,271|279,279|283,284|289,289|297,297|299,300|303,303|312,312|316,316|323,323|331,345|348,348|351,351|353,354|370,370|373,373|380,380|404,406|428,428|432,432|450,450|452,452|463,463|483,483|485,492|511,515|518,519|526,526|539,544|547,547|549,550|553,554|574,574|598,599|602,602|606,606|612,612|616,617|628,628|631,631|633,633|636,637|645,645|647,648|656,656|658,658|674,674|677,678|693,693|704,704|706,708|711,712|720,720 Q:0,0|3,4|7,8|13,13|15,16|19,21|27,36|39,41|43,43|46,47|49,57|60,64|67,67|70,70|72,74|79,81|84,86|92,103|106,147|149,150|152,155|158,159|161,168|173,173|176,186|188,193|195,196|202,202|204,218|220,224|226,229|232,233|239,249|252,260|266,266|268,270|272,278|280,282|285,288|290,296|298,298|301,302|304,311|313,315|317,322|324,330|346,347|349,350|352,352|355,369|371,372|374,379|381,403|407,427|429,431|433,449|451,451|453,462|464,482|484,484|493,510|516,517|520,525|527,538|545,546|548,548|551,552|555,573|575,597|600,601|603,605|607,611|613,615|618,627|629,630|632,632|634,635|638,644|646,646|649,655|657,657|659,673|675,676|679,692|694,703|705,705|709,710|713,719|721,725 S?-EE??SS--??T-TB-?TTS?????SSSTTGGGGS??GGG?B??SS?EEEESSSSS-?SEEEE??S--S?EEE????SSS??EEE?????SEEEEEGGGTTS??EEEEEEEETTEEEEEEEETTEEEEEEEEEEETTBSSEEEEEE-EE?EEEE-?SS?EEEEEETT????S??SEEEEEEESSS?EEEEEE?SS-----S?EEEEEEETTEEEESS?EEEEE-EEEE??SG-----GGHHHHHHTTT??EEEEEEEEE-????S?EEE-EEEEEES?SSS??EEEE?HHHHHHB?G--GG?EEEEEEEE?SSS?EEEEEE?SEEEEEE?--------??????SS?SS?S??GGGHHHHHHHHHHHH-TS?HHHHHS?SSHHHHHHHHHHHHHHHHHHHTH???HHHHHHHHHHHHHHHHHHHTT?SSS?EEEETTTTEEEESTTSS?S?TTGGGGGGGT?SHHHHHHHHHHHHHHHHHH?T--------TTTHHHHHHHHHHHHHHH-----HB??TTSTTS?BTSSEETTTTEE??????TT?T??EE??HHHHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHHHHHHHHTB??TT?TTS?HHHHT-TSB??EEESSEEESS?SS?S?HH--HHHHGGG?S??HHHHTTS?H-HHHHHHHHHTHHHHG-GG??STHHHHHHHHHTTT?HHHHHHHHTT-S???TT??HHHHHHH-HHTST 4K3A|A PF03641.9_Lysine_decarbox_seed 32 177 !Q:9,10|14,23|32,68|71,72|89,89|95,95|97,98|117,124|129,129|133,135|146,146|155,155|161,161 Q:0,8|11,13|24,31|69,70|73,88|90,94|96,96|99,116|125,128|130,132|136,145|147,154|156,160|162,176 HHHHHHHHH--HTT??--------EEEEEETT???-????------------------------?????EE--EEESSHHHHHHHHHHT?SEEEE?S??HHHHHHHHHHHHHHHHTS?---??-?EEEE?GGG---TTHHHHHHHH-HHHHTTSS?HHHHT-TEEEESSHHHHHHHH 1WEK|A PF03642.8_MAP_seed 10 88 !Q:9,9|12,12|20,20|23,23|43,45|54,54|65,65|73,79 Q:0,8|10,11|13,19|21,22|24,42|46,53|55,64|66,72|80,87 EEEEEEETT?SS?EEEEEEE?TT?EEEHHHHHHHHHHHHHHHH???HHHHHHSS?EEEEEEETTS?EEEEETT???????EEEGGGEE 3KM9|X PF03643.10_Vps26_seed 8 410 !Q:17,17|23,23|25,30|33,33|41,41|44,45|59,60|65,65|71,82|89,89|93,120|124,124|134,134|139,139|141,141|144,144|150,150|152,159|161,162|165,165|179,180|183,184|186,186|196,214|216,274|293,293|297,300|304,304|306,312|323,326|328,328|344,345|349,349|361,371|382,386|409,409 Q:0,16|18,22|24,24|31,32|34,40|42,43|46,58|61,64|66,70|83,88|90,92|121,123|125,133|135,138|140,140|142,143|145,149|151,151|160,160|163,164|166,178|181,182|185,185|187,195|215,215|275,292|294,296|301,303|305,305|313,322|327,327|329,343|346,348|350,360|372,381|387,408 TTTTEEEEEEETTGGGS?EEEEE?T------TS?EEEEEEE?TT??EEEEEEEEESSSS??EEES?EEEEE------------EEEEEE?STT?--------------------------?EEE-EEEEEEEEE?SEEE?S?EE-EEEEE?S????----S??EE?SSEEEEEEEEEEE??SS--S?EEEEEEEEE?-------------??---B???---------------------------------------???------------??EEEEEEETTTEEEEEEES?SEE----ETT?E-------EEEEEEEEEE?---S?EEEEEEEEEEEEEES?-GGG?EEEEEEEEEEE???????????EEEEEESTTT?????EEEEETTEEEEEEEEEEEEETT? 2FAU|A PF03644.8_Glyco_hydro_85_seed 36 572 !Q:0,0|4,4|6,7|10,10|12,18|21,21|23,23|25,25|27,28|31,36|40,40|46,48|53,73|78,80|92,93|98,102|106,107|112,113|122,124|128,131|134,144|157,158|160,160|166,167|169,193|212,212|214,224|226,240|247,248|250,250|254,254|256,258|261,262|271,281|287,288|294,294|296,297|299,345|358,358|362,373|380,380|385,398|401,404|410,410|413,419|421,424|432,432|439,447|449,460|476,476|480,480|484,498|503,505|511,512|515,517|519,553|557,557|560,563 Q:1,3|5,5|8,9|11,11|19,20|22,22|24,24|26,26|29,30|37,39|41,45|49,52|74,77|81,91|94,97|103,105|108,111|114,121|125,127|132,133|145,156|159,159|161,165|168,168|194,211|213,213|225,225|241,246|249,249|251,253|255,255|259,260|263,270|282,286|289,293|295,295|298,298|346,357|359,361|374,379|381,384|399,400|405,409|411,412|420,420|425,431|433,438|448,448|461,475|477,479|481,483|499,502|506,510|513,514|518,518|554,556|558,559|564,571 ?SSS?S--SS?B-------TT?B-S?S--SS??-???GGG?SEEEE???BTTT---------------------BSEE???HHHHHHHHHTT??EEEE-----EEE??GGGT??HHHHHHHT???TTS?--?HH-----------HHHHHHHHHHHT??E-EEEEE??S--?--------??------------HHHHHHHHHHHHHHHHHS?T-----------T?--------------EEEEES?-B?TTS?B???SS??TTTGGGTE-----------ETTEE??SEEEE?S??S?---------------------------------------------?HHHHHHHHHTTS?GGG------------EEEEEE?TTTG--------------GG????GGGTS?SS-------S--??SSEEEEE?TTHHHH---------T?-----------SSHHHHHHHHHHHHT?TTS?TTS?-------------?TTSS???GGGTS??EE???S-----------------------------------SSE-EE????SEESSEEE 3FHQ|A PF03645.8_Tctex-1_seed 104 201 !Q:0,0|2,8|16,16|26,26|28,38|40,40|59,59|62,67|69,84|86,86|98,143|148,149|156,156|158,158|160,164|167,169|175,184|189,189|199,200 Q:1,1|9,15|17,25|27,27|39,39|41,58|60,61|68,68|85,85|87,97|144,147|150,155|157,157|159,159|165,166|170,174|185,188|190,198 ?H-------HHHHHHH-HHHHHHHHS-S-------??-?H-HHHHHHHHHHHHHHHHHH-HH------H----------------T?SSEEEEEEEEE?---------------------------------------------TTTS??EEEEEE?S?S-----SS???EEEEE----------ESSS?EEEEEEEEE?? 2PG1|E PF03646.10_FlaG_seed 139 168 !Q:0,1|5,8|22,44|47,61|65,65|68,68|81,81|84,89|101,101|119,119|128,131|137,146|149,159|162,162|165,165 Q:2,4|9,21|45,46|62,64|66,67|69,80|82,83|90,100|102,118|120,127|132,136|147,148|160,161|163,164|166,167 ??STT????HHHHHHHHHHHHS------------------?????SS???------??--??HHH-HH-HHHHHHHHHHTT-SS??----EEEEEEEETTE-EEEEEEETTTTEEEEEE?HHHHHHHH----HHHHH----------HH-----------HH-HS?TT 2HC5|A PF03647.8_Tmemb_14_seed 61 127 !Q:20,20|22,23|41,46|52,58|69,69|74,86|95,107|111,111 Q:0,19|21,21|24,40|47,51|59,68|70,73|87,94|108,110|112,126 HHHHHHHHHHHHHHHHHHHT?S??HHHHHHHHHHHHHHHHH------HTSSS-------STHHHHHHHH-HHHH-------------HHHHTSSS?----?????-??SSS?HHHHHHHHHHHHHHS 2LOS|A PF03648.9_Glyco_hydro_67N_seed 38 139 !Q:2,8|10,10|21,22|27,29|31,32|53,58|61,61|64,65|69,75|80,80|84,84|87,89|94,95|106,106|125,125 Q:0,1|9,9|11,20|23,26|30,30|33,52|59,60|62,63|66,68|76,79|81,83|85,86|90,93|96,105|107,124|126,138 TT????-??S?HHHHHHHHHH??EEEE???S--HHHHHHHHHHHHHHHHHTTS??--?-EE?SS??SSE-------EEEE?TTT?HH---HHHT??THHHHTTTTT?EEEEEEEETTEEEEEEEE-SSHHHHHHHHHHH 1K9E|A PF03652.10_UPF0081_seed 174 200 !Q:0,0|24,24|29,30|32,34|36,37|40,46|48,50|62,70|73,73|78,91|93,93|95,95|98,99|106,106|118,126|128,133|137,140|143,144|147,148|151,163|166,167|169,177|179,184 Q:1,23|25,28|31,31|35,35|38,39|47,47|51,61|71,72|74,77|92,92|94,94|96,97|100,105|107,117|127,127|134,136|141,142|145,146|149,150|164,165|168,168|178,178|185,199 ?EEEEEEEETTEEEEEEEETTTTE-EEEE??S?-?B--TT-------B-??HHHHHHHHHHT------?--EE-EEEE???---------??S-S-SS??TTHHHH-HHHHHHHHHHH---------T?---?-EEE????SS??SS?-SS?--?-?-------SS?-S?-----???S?---??SSHHHHHHHHHHHHH 1IV0|A PF03656.8_Pam16_seed 3 138 !Q:0,62|72,73|78,79|96,96|101,102|121,121|126,137 Q:63,71|74,77|80,95|97,100|103,120|122,125 -------------------------------------------------------------??HHHHHHHTT??GGGT??SHHHHHHHHHHHHHHT?GGGT??HHHHHHHHHHHHHHHHHH-HHHH?----------- 2GUZ|B PF03657.8_UPF0113_seed 4 177 !Q:0,0|5,6|22,26|29,32|47,47|57,60|74,74|78,78|84,84|94,94|97,97|102,102|113,114|116,116|125,125|128,128|131,131|136,136|140,140|146,153|156,156|159,159|169,176 Q:1,4|7,21|27,28|33,46|48,56|61,73|75,77|79,83|85,93|95,96|98,101|103,112|115,115|117,124|126,127|129,130|132,135|137,139|141,145|154,155|157,158|160,168 ?EEEE??HHHHHHHHHHHHTTE-----EE????EEEEESSSEEEEEE?HHHHHHTTT????GGGTEEEEEEEEE?TTS?EEEEE?HHHHTTEEE?SS-EEEE?HHHHHHHHTT??B?GGGEEEEE?SS?SE-EEEE?TTS?EEEEE--------EE?TT?STTSEEEEE???????? 1SQW|A PF03658.9_Ub-RnfH_seed 10 86 !Q:23,23|38,38|41,42|53,53|55,58|61,61|63,64|67,67|72,85 Q:0,22|24,37|39,40|43,52|54,54|59,60|62,62|65,66|68,71 EEEEEEEEETTEEEEEEEEEETT?BHHHHHHHHTHHHH?TT??TTTSEEEEEE?S??--TT?B??TT?EEEE?????????????? 2HJ1|A PF03660.9_PHF5_seed 19 133 !Q:0,0|3,4|7,8|10,13|19,19|22,22|28,29|33,44|47,47|57,63|69,69|74,79|83,89|92,92|95,95|107,110|112,112|114,114|117,117|122,127|132,132 Q:1,2|5,6|9,9|14,18|20,21|23,27|30,32|45,46|48,56|64,68|70,73|80,82|90,91|93,94|96,106|111,111|113,113|115,116|118,121|128,131 -SS??TT??B????EEEEE?EE?GGGTT??TTT?---?????--?EE?EEEHHHHTS-------STTSB?TTTS------SSB??-----EE?EE?HHHHHHTSTTS????B?S?SS?SSTT---???SSTT? 2K0A|A PF03663.9_Glyco_hydro_76_seed 90 581 !Q:0,0|2,4|23,23|26,34|44,45|47,48|54,56|74,82|113,114|119,121|129,129|131,133|137,138|151,151|156,157|159,165|167,169|187,187|190,195|199,199|201,201|204,205|209,209|211,214|235,237|240,243|254,254|259,260|264,270|272,275|278,279|281,281|283,283|286,286|290,290|293,293|298,302|305,306|309,315|333,340|342,361|375,383|389,390|406,436|438,438|441,441|460,472|487,510|516,516|520,520|522,546|549,549|553,556|558,558 Q:1,1|5,22|24,25|35,43|46,46|49,53|57,73|83,112|115,118|122,128|130,130|134,136|139,150|152,155|158,158|166,166|170,186|188,189|196,198|200,200|202,203|206,208|210,210|215,234|238,239|244,253|255,258|261,263|271,271|276,277|280,280|282,282|284,285|287,289|291,292|294,297|303,304|307,308|316,332|341,341|362,374|384,388|391,405|437,437|439,440|442,459|473,486|511,515|517,519|521,521|547,548|550,552|557,557|559,580 ?H---HHHHHHHHHHHHHHHHBS?ST---------TSSBBSEES??S??GGGGB-??HHHHHHHHHHHHHHHHH---------TTTSTTHHHHHTTHHHHHHHHHTTEEEETT--EEEE-?-SSSSTTS?E---EHH--HHHHHHHHHHHH-HHHH??H-------H---HHHHHHHHHHHHHHTTB?SG------GGS?B?SE--EES-S????EEHHHHHHHHHHHHHHHHHH-??HH----HHHHHHHHHH-HHHH--HSB------?T----TT--S?B?SE-EEE?SS?TTSE-----EE--EE??---??HHHHHHHHHHHHHHHHH--------H-------------??-----HHHHHHHHHHHHH---------HHHHH--EEEEEETTTTEEEEE-------------------------------E?SS?HHHHHHHHHHHHHHHHHH-?-?-----?---HHHHHHHHHHHHHH------------------------HSTTB?TTS?B------------------------?TT?TTS????S?EEHHHHHHHHHHHHHHHHHHHT 3K7X|A PF03671.9_Ufm1_seed 2 76 !Q:0,1|10,11|15,17|22,22|40,41|52,56|69,69 Q:2,9|12,14|18,21|23,39|42,51|57,68|70,75 ??EEEEEESS??SSS???EEEE?SSSBHHHHHHHHHHHTT??SSSEEEEESS?????TTSBHHHHHHHT?SEEEEE 1WXS|A PF03678.9_Adeno_hexon_C_seed 23 254 !Q:0,0|4,4|6,9|12,12|17,19|21,21|24,25|35,36|39,40|45,47|53,56|59,60|63,66|68,69|74,77|82,83|97,97|100,100|104,104|109,112|117,120|124,125|130,131|145,146|149,150|152,154|158,158|162,162|170,171|173,174|183,183|187,191|196,197|202,205|209,210|216,216|221,225|227,236|238,239|245,246|251,253 Q:1,3|5,5|10,11|13,16|20,20|22,23|26,34|37,38|41,44|48,52|57,58|61,62|67,67|70,73|78,81|84,96|98,99|101,103|105,108|113,116|121,123|126,129|132,144|147,148|151,151|155,157|159,161|163,169|172,172|175,182|184,186|192,195|198,201|206,208|211,215|217,220|226,226|237,237|240,244|247,250 ?STT?B????SS?EEEE???B?SS??EEEEEEEEE??TT??EEEE???BSTTS????SS??TT????S??GGGT????SSTT??EEEEEETTTEESS?TT?SSS?SSEE????SSSS---?STT??TTSS??TTTTTTTTTTTTS??SS??S???GGG?SSS?SSSSEEE??B??TTSSSSSS-STT?????STTS--SSSS????TTT??TTSSS?SSSS--???S??????????S??SSSSS??STTS??? 2OBE|A PF03681.10_UPF0150_seed 144 63 !Q:0,3|8,11|15,19|28,32|36,39|62,62 Q:4,7|12,14|20,27|33,35|40,61 ????EEEE---?TTS?----EEEEEGGG-----TEE----EEESSHHHHHHHHHHHHHHHTT? 2DSY|A PF03685.8_UPF0147_seed 23 87 !Q:0,3|16,16|22,22|26,26|42,42|46,46|64,64|67,68|85,86 Q:4,15|17,21|23,25|27,41|43,45|47,63|65,66|69,84 ????HHHHHHHHHHHH-HHHHT?TTS?HHHHHHHHHHHHHTT?TTS?HHHHHHHHHHHHHHHTT?TT??HHHHHHHHHHHHHHHT?? 2QSB|A PF03686.8_UPF0146_seed 6 135 !Q:12,12|22,22|25,26|37,38|44,44|47,47|49,56|62,64|68,69|84,85|101,101|107,107|112,116|119,119|134,134 Q:0,11|13,21|23,24|27,36|39,43|45,46|48,48|57,61|65,67|70,83|86,100|102,106|108,111|117,118|120,133 HHHHHHHHHHHS?SSSEEEEET?TT??HHHHHHHHHS??EEEEE?SS?S--------STTEE???SSS??HHHHTTEEEEEEES??TTTHHHHHHHHHHHT?EEEEE?BTTB?????TT?EEEEETTEEEEEEE? 2K4M|A PF03688.9_Nepo_coat_C_seed 21 187 !Q:1,1|4,5|7,7|13,15|18,21|25,26|28,30|32,32|35,48|56,58|74,74|81,82|84,85|87,87|91,94|100,101|107,109|115,120|122,123|130,132|135,136|144,150|153,155|159,159|161,162|179,179|186,186 Q:0,0|2,3|6,6|8,12|16,17|22,24|27,27|31,31|33,34|49,55|59,73|75,80|83,83|86,86|88,90|95,99|102,106|110,114|121,121|124,129|133,134|137,143|151,152|156,158|160,160|163,178|180,185 S?SS??E-EEEEE---ES????TTT??B???B?SS?????--------?SSSEEEE???HHHHHHHTEEEEEEE-EEEEEE??B-?S?TTT????EEEEE??STTSS???EEEES------S??EEEEEE???SS??SSTTSSS?--????EE---EEB?S??TTTBTEEEEEEEEEEE-EEEEEE? 2Y7T|A PF03689.10_Nepo_coat_N_seed 21 95 !Q:8,9|12,13|16,16|31,31|42,44|47,48|56,59|63,64|74,76|79,79|82,82|84,86|93,95 Q:0,7|10,11|14,15|17,30|32,41|45,46|49,55|60,62|65,73|77,78|80,81|83,83|87,92 EEEEEEEE??TT??TT?EEEEEEHHHHHHHS?HHHHHHHHHH?--EE??EEEEEEE????TTS??EEEEEEESS???HH-HH?S???HHHHTS??- 2Y7T|A PF03693.9_RHH_2_seed 5 81 !Q:0,3|7,9|25,25|60,60|65,66|77,80 Q:4,6|10,24|26,59|61,64|67,76 ????EEE???HHHHHHHHHHHTTTS?SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?EESS??HHHHHHHHHH???? 3KXE|C PF03695.8_UPF0149_seed 169 328 !Q:7,8|11,17|21,21|23,29|44,48|50,55|57,57|62,64|70,89|95,100|109,123|134,139|145,182|202,204|207,207|209,209|212,229|233,234|237,243|251,253|260,268|271,288|292,293|304,304|314,319|324,327 Q:0,6|9,10|18,20|22,22|30,43|49,49|56,56|58,61|65,69|90,94|101,108|124,133|140,144|183,201|205,206|208,208|210,211|230,232|235,236|244,250|254,259|269,270|289,291|294,303|305,313|320,323 HHHHHHH--HH-------HTT?S?-----?HHHHHHHHHHHHHT-----T----??S-TTHH---HHHHH--------------------HHSTT????--TTTHHHHH---------------HHHHHHHHHH------TTTTS???-------------------???????--??-----HHHHHHHHHHHHHHHHHHH---HH-H?TT------------------GGG??HH-------HHHHHHH---HHHHTT???-----?SS?----------------?SHH--HHHHHHHHHH-HHHHHHHHH------HHHH???? 4GYT|A PF03702.9_UPF0075_seed 9 385 !Q:0,0|7,8|11,11|24,27|38,38|40,41|54,56|87,88|92,93|98,99|108,108|110,111|118,119|130,130|134,135|145,150|159,164|180,180|184,185|206,209|212,212|222,224|239,240|243,246|259,276|300,300|303,305|316,316|327,327|330,330|341,342|362,364|366,366|371,372|375,379|383,384 Q:1,6|9,10|12,23|28,37|39,39|42,53|57,86|89,91|94,97|100,107|109,109|112,117|120,129|131,133|136,144|151,158|165,179|181,183|186,205|210,211|213,221|225,238|241,242|247,258|277,299|301,302|306,315|317,326|328,329|331,340|343,361|365,365|367,370|373,374|380,382 ?EEEEEE??SS?SEEEEEEEEESS----SEEEEEEEEE-E??HHHHHHHHHTTS?-?BTHHHHHHHHHHHHHHHHHHHHHHHHHHTT??GGG??EEEE??EEEEEEGG-G--TEEEEE??HHHHHHHHSS?EEE??SHHHHHTTS??????HHHHHHHH??????EEEEEESSEEEEEEE?TTS??EEEEEEESSHHHHHHHHHHH?--?SS?GGGHHHHTS???HHHHHHHHTSHHHH??SS????TTTSSHHHHHHH????????----------HHHHHHHHHHHHHHHHHHHHHHH?TT-??EEEEESGGGG?HHHHHHHHHH?TT-SEEEEGGGGT??TTTHHHHHHHHHHHHHHTT???S?HHHH??SS?????EEE?? 3QBX|A PF03704.12_BTAD_seed 64 164 !Q:9,9|21,22|37,38|48,53|78,81|88,91|94,95|111,111|127,127|148,152 Q:0,8|10,20|23,36|39,47|54,77|82,87|92,93|96,110|112,126|128,147|153,163 BHHHHHHHH-HHHHHHHHHTT-?HHHHHHHHHHHHTT??SSTTGGGTT------STTHHHHHHHHHHHHHHHHHHHHH----HHHHTT---?HH--HHHHHHHHHHHHSTT?HHHHHHHHHHHHTTT?HHHHHHHHHHHHHHHHHHHS?-???HHHHHHHHHHH 2WQH|A PF03705.10_CheR_N_seed 77 62 !Q:0,0|16,20|22,22|34,34|42,44|53,55|58,58|61,61 Q:1,15|21,21|23,33|35,41|45,52|56,57|59,60 ?HHHHHHHHHHHHHHH?????G-GGHHHHHHHHH-HHHHHHT???HHHHHHHH---HH?TT? 1AF7|A PF03709.10_OKR_DC_1_N_seed 82 134 !Q:15,15|18,18|37,39|46,58|80,81|87,87|90,90|96,96|104,104|106,108|114,114|118,118 Q:0,14|16,17|19,36|40,45|59,79|82,86|88,89|91,95|97,103|105,105|109,113|115,117|119,133 HHHHHHHHHHHHHHH-TT?EEEEESSHHHHHHHHTTT???SEEEEE???---------?SHHHHHHHHHHHHHHHHHSTT??EEEEE?HH-HHHHT?SHHHHHH?S---EEEET-TTS?HHHHHHHHHHHHHHH 2VYC|A PF03710.10_GlnE_seed 22 309 !Q:10,10|20,24|29,29|34,34|41,43|46,46|59,59|62,62|64,66|68,95|122,134|166,168|175,175|178,179|193,195|198,199|207,209|212,214|217,217|222,223|242,243|248,248|250,251|254,254|264,264|280,281|291,291|296,298 Q:0,9|11,19|25,28|30,33|35,40|44,45|47,58|60,61|63,63|67,67|96,121|135,165|169,174|176,177|180,192|196,197|200,206|210,211|215,216|218,221|224,241|244,247|249,249|252,253|255,263|265,279|282,290|292,295|299,308 HHHHHHHHHH?HHHHHHHHH?----GGGG-GGGG?HHHHSS???TT?HHHHHHHHTTTS?TT?H---H----------------------------HHHHHHHHHHHHHHHHHHHHHHHTSS?------------GGGHHHHHHHHHHHHHHHHHHHHHHHHHHHH-??BGGGTT?SS?-SEEEEEEHHHHTT???TT??EEEEEEE???TT?--BB-SSSS??BHHHHHHHHHHHHHHHHH??BTTB?S??EE?TTSTTGGGS?SEEEHHHHHHHHHHT??HHHHHHHHT?EEEE-??HHHHHHHHHH 1V4A|A PF03711.10_OKR_DC_1_C_seed 32 137 !Q:0,0|7,7|14,14|41,42|45,46|49,49|51,51|63,63|72,72|75,75|78,78|80,80|89,90|92,92|98,98|102,102|122,123|128,128|131,131|135,135 Q:1,6|8,13|15,40|43,44|47,48|50,50|52,62|64,71|73,74|76,77|79,79|81,88|91,91|93,97|99,101|103,121|124,127|129,130|132,134|136,136 ?HHHHHH?TTTTSS?BHHHHHHHHHHHHHHHTHHHHHHHHH--HS??EE?S?HHHHHHHHHHT?EEEEEGGG?BT?BB?S?BEEETTTS??B?TTEEB?STT?HHHHHHHHHHHHTTSSTTS??EEES?EE?SSS?E 2VYC|A PF03712.10_Cu2_monoox_C_seed 25 192 !Q:10,10|13,17|20,20|23,23|25,25|34,37|40,40|44,49|56,57|73,77|85,85|89,94|99,100|106,106|109,109|118,119|121,122|124,133|136,136|140,140|147,148|157,161|166,167|173,174|177,177|180,182|187,188 Q:0,9|11,12|18,19|21,22|24,24|26,33|38,39|41,43|50,55|58,72|78,84|86,88|95,98|101,105|107,108|110,117|120,120|123,123|134,135|137,139|141,146|149,156|162,165|168,172|175,176|178,179|183,186|189,191 SEEEEEEEEE?SS?----EE?TT?S?EEEEEEEE??--SS?EEE------EEEEEE??TTEEEEEEEEEETTE-----EEEEEEE?TTS?--???EEEE--EEEEE?TT?EEEEEEEE??T--T?---------SS?EEB?SSTTSB??EEEEEEEE-----ETTT??SEEEE??BS?GG---GGGG??GGG 1YJL|A PF03713.8_DUF305_seed 86 233 !Q:23,25|28,30|60,61|64,64|67,68|74,111|113,125|127,133|135,137|147,148|150,162|189,197|199,201|203,206|211,211 Q:0,22|26,27|31,59|62,63|65,66|69,73|112,112|126,126|134,134|138,146|149,149|163,188|198,198|202,202|207,210|212,232 HHHHHHHHHHHHHHHHHHHHHHH---TT???HHHHHHHHHHHHHHHHHHHHHHHHHHHTT??SS?SS-?TTGGG--------------------------------------T?????????????T-------T???HHHHHHHHH??H-------------HHHHHHHHHHHHHHHHHHHHHHHHHH---------H---H?-??HHHH-HHHHHHHHHHHHHHHHHHHHH 3BT5|A PF03714.9_PUD_seed 39 145 !Q:0,0|9,13|16,20|33,58|62,64|67,67|69,69|81,82|85,88|97,97|104,111|113,113|115,115|120,123|136,139|143,145 Q:1,8|14,15|21,32|59,61|65,66|68,68|70,80|83,84|89,96|98,103|112,112|114,114|116,119|124,135|140,142 ?EEEEEEEE?----TT--???TTEEEEEEEEES?????---------------------EEE???EE?S-SSEEEEEEESS??SE----EEEEEEET-TTTEES--------S?S?EEEE?---BTTEEEEEEETT????BSS??- 2J71|A PF03717.10_PBP_dimer_seed 165 496 !Q:3,7|10,18|21,28|30,30|40,46|51,52|55,56|64,113|121,129|131,133|136,137|139,199|210,210|218,218|221,229|240,240|252,253|260,260|262,264|281,281|291,317|320,321|323,326|339,357|365,365|369,369|373,373|376,377|380,382|389,390|392,393|395,407|412,412|423,444|446,447|450,452|454,458|471,471|473,473|478,478|482,484|487,489|496,496 Q:0,2|8,9|19,20|29,29|31,39|47,50|53,54|57,63|114,120|130,130|134,135|138,138|200,209|211,217|219,220|230,239|241,251|254,259|261,261|265,280|282,290|318,319|322,322|327,338|358,364|366,368|370,372|374,375|378,379|383,388|391,391|394,394|408,411|413,422|445,445|448,449|453,453|459,470|472,472|474,477|479,481|485,486|490,495 EEE?????EE--------?TT------??E-EEEEEEEEE-------EEEE??TT??HHHHHHH--------------------------------------------------HHHHHHH?-?----??G---GG??H-------------------------------------------------------------HHHHHHHHHH?HHHHHTT?HH---------HHHHHTTSSS?HHHHHHHHHTT??TTGGGG?S---HHHHHHHHHHHHHTSS?SSSEEEEEE---------------------------EE??H----HHHHHHHHHHHH-------------------STTEEEE-EEE-EEE?TT--TT---TTHHHH??B??S-------------SSSS?GGGHHHHHTT----------------------T??TT???B----?SSHHHHTHHHHS?B?EEEE-EEE--?TT??-EEEEEE- 2Z2M|A PF03718.8_Glyco_hydro_49_seed 4 633 !Q:0,16|23,26|31,32|36,38|41,41|45,45|58,62|66,67|71,71|77,77|79,79|85,85|88,90|92,92|95,97|99,99|107,107|119,119|130,134|146,147|152,152|156,156|162,164|167,167|184,186|190,193|200,200|218,220|223,226|229,232|239,240|245,245|250,250|258,258|265,265|267,267|270,271|274,274|278,279|282,283|286,287|292,292|300,300|304,307|310,310|317,317|321,321|325,325|328,328|336,339|341,343|348,349|354,354|356,357|362,362|368,368|372,373|376,376|381,381|385,388|400,402|406,409|411,412|415,415|427,427|431,432|436,436|446,446|450,450|454,455|458,460|474,476|479,480|485,485|491,493|495,501|505,508|515,515|525,525|529,529|535,536|552,553|555,555|557,558|562,562|565,565|569,571|574,588|603,606|610,610|617,617|620,620|622,622|629,629|632,632 Q:17,22|27,30|33,35|39,40|42,44|46,57|63,65|68,70|72,76|78,78|80,84|86,87|91,91|93,94|98,98|100,106|108,118|120,129|135,145|148,151|153,155|157,161|165,166|168,183|187,189|194,199|201,217|221,222|227,228|233,238|241,244|246,249|251,257|259,264|266,266|268,269|272,273|275,277|280,281|284,285|288,291|293,299|301,303|308,309|311,316|318,320|322,324|326,327|329,335|340,340|344,347|350,353|355,355|358,361|363,367|369,371|374,375|377,380|382,384|389,399|403,405|410,410|413,414|416,426|428,430|433,435|437,445|447,449|451,453|456,457|461,473|477,478|481,484|486,490|494,494|502,504|509,514|516,524|526,528|530,534|537,551|554,554|556,556|559,561|563,564|566,568|572,573|589,602|607,609|611,616|618,619|621,621|623,628|630,631 ----?-----???????BSSSEE????TTEE??SSS???TT?EEB?SSEEEEEEETTS-??-?EEE??EEE?GGGGT?S?SSTTS?TT???S?TT???S?SSHHHHT?EEEEEEEEESS?EEEEEEETTS?????GGGEEEESTTS??EEEE?TTS?EEEEE???TT?EEEEEEEGGGEEEEEE?--SSS----EESSSS-EEEEEEESEEEEEEEEE???GG----GS????TTTEEE??SEEE?TTTT?SSSEEEE?SEEEEE?B?TT??BS?SSS??EE??TT??EEEE?TTEEEES?EEE?--?SS?EEEESS?EEE?TTS?TT?BTTTTTB----S???TTTB??SEEE?S??SSEE-EEEES?EEE??SS?SEEE?SSS?---EEEEEEEEEEE???STT????B??TT?EEEEEEEEESS?SEE??STT?EEEEEEEEE?SSS?SEE??SS???EEEEEEEEEEEEE???SS??TTTT?EEEEE???S-------SSS-???EEEEEE-EEEEEEEEE?SSB?EEEEE??SEEEEEEEEEEEEET--T?B??STT?TT?EEE???TT?-------------?EEEEEEEEEETTEE?--?TTT?STTSSS?EE-E?GGGTTT?EE? 1OGO|X PF03719.10_Ribosomal_S5_C_seed 114 81 !Q:0,0|11,12|14,15|18,19|22,23|25,25|36,37|39,42|45,46|48,48|50,53|68,70|79,80 Q:1,10|13,13|16,17|20,21|24,24|26,35|38,38|43,44|47,47|49,49|54,67|71,78 ?EEEETTEEEE??B??TT??EE??S-HHHHHHTTTT??S----EE??B?S-???HHHHHHHHHHHHHH???SSSHHHHT-? 3KIX|e PF03720.10_UDPG_MGDP_dh_C_seed 161 172 !Q:3,4|8,9|12,15|18,18|31,33|35,40|42,42|47,47|49,50|53,53|62,70|74,99|105,107|111,112|119,119|125,125|127,130|136,136|138,141|150,153|156,157|164,165|167,167|169,169 Q:0,2|5,7|10,11|16,17|19,30|34,34|41,41|43,46|48,48|51,52|54,61|71,73|100,104|108,110|113,118|120,124|126,126|131,135|137,137|142,149|154,155|158,163|166,166|168,168|170,171 EEE??SSS--TT????TT?HHHHHHHHHHTT---T?-----E-EEEE?S--SS?HHHHHHHH?????????HHH--------------------------HHEEE--?SSH--HHHHTT?SEEEE?S-??-GGGGG-S---?HHHHHHHS-?--SS?-EEEESS--S?S-TT 3PHL|A PF03721.9_UDPG_MGDP_dh_N_seed 27 210 !Q:0,0|6,7|23,25|31,31|33,33|44,45|48,49|64,64|70,70|78,78|84,88|90,90|92,95|100,102|119,119|122,123|128,128|130,132|150,158|168,173|184,184|186,186|198,203 Q:1,5|8,22|26,30|32,32|34,43|46,47|50,63|65,69|71,77|79,83|89,89|91,91|96,99|103,118|120,121|124,127|129,129|133,149|159,167|174,183|185,185|187,197|204,209 ?EEEEE??STTHHHHHHHHHHTT--?EEEEE?S?HHHHHHHHTT??SS??TTHHHHHHHHHHHT?EEEES?HHHHHHT?SEEEE?????B?T----TSSB-??HHHHHHHHHHHHHHHH?SS??EEEE?S???TTHHHHTHHHHHHHHHS??-------BTTTBEEEE??????TTSHHHHHHS?S?EEEEESSHHHH------HHHHHH 1EVY|A PF03722.9_Hemocyanin_N_seed 111 143 !Q:18,21|25,25|34,40|49,51|53,53|57,59|63,63|71,75|79,81|102,103|121,121|136,136|142,142 Q:0,17|22,24|26,33|41,48|52,52|54,56|60,62|64,70|76,78|82,101|104,120|122,135|137,141 HHHHHHHHHHHTTSSTTS?--?TTS-HHHHHHHH??-----TGGGGGGB---S?HHH---HHH-HHHHHTT?-???TTS???TTSHHHHHHHHHHHHHHHTB--SSHHHHHHHHHHHHHHS?HHHHHHHHHHHHHH?GGGTT? 1HC1|A PF03723.9_Hemocyanin_C_seed 163 333 !Q:0,3|6,11|14,15|26,28|32,33|49,49|54,56|58,82|84,84|86,86|97,99|102,103|110,116|120,120|134,134|137,138|141,143|151,151|162,162|169,171|178,178|182,182|184,187|194,196|198,217|226,226|229,229|233,235|238,238|240,240|256,266|269,269|271,271|278,279|281,281|284,285|287,288|290,290|298,308|315,319|332,332 Q:4,5|12,13|16,25|29,31|34,48|50,53|57,57|83,83|85,85|87,96|100,101|104,109|117,119|121,133|135,136|139,140|144,150|152,161|163,168|172,177|179,181|183,183|188,193|197,197|218,225|227,228|230,232|236,237|239,239|241,255|267,268|270,270|272,277|280,280|282,283|286,286|289,289|291,297|309,314|320,331 ????HH------HH??TTEEEEEEEE---ESS--STTEEEEEEEEEEEE?TTTS-??T-------------------------T?S?EEEEEEEEEE???EE--EEEEEE------?SSS?EEEEEEEEEEESB?SS--SB???HHHHHHH?EEEEEEEEEE?SEEEEE---EEEGGG?TTB?S????HHHHHH???S???----------------?SSTTTSSB?ST-TSS???BT-T?EEEEEEEEEEEHHHH??-?????---SS?S?TTHHHH??T-TS??S??S?TTTTTTS???-------?SSHHHH-??--TTEEEEEEEEEE? 1HC1|A PF03724.11_META_seed 122 184 !Q:9,11|16,16|20,21|23,27|33,35|39,47|53,69|72,72|79,82|84,85|96,96|100,109|111,115|119,123|125,125|128,135|138,138|152,154|159,164|168,175|181,181 Q:0,8|12,15|17,19|22,22|28,32|36,38|48,52|70,71|73,78|83,83|86,95|97,99|110,110|116,118|124,124|126,127|136,137|139,151|155,158|165,167|176,180|182,183 STTSEEEEE---EEEE?SSS?-B?????TTSSS-??EEE---------EESTT-----------------SS-SEEEEE---?S--SSEEEEEEEE-ETT----------E-----EEE?----S?EE?????--?SH-HHHTHHHHHHTTS?-?SEEE?-?--?SSS-------?EEEEE?TT 2KTS|A PF03725.10_RNase_PH_C_seed 107 142 !Q:1,2|11,12|14,25|28,34|39,40|42,42|45,62|66,69|76,83|86,86|88,97|99,100|106,113|116,119|122,124|127,127 Q:0,0|3,10|13,13|26,27|35,38|41,41|43,44|63,65|70,75|84,85|87,87|98,98|101,105|114,115|120,121|125,126|128,141 S??EEEEEEEE--T------------TE-------EEES??T-TT------------------TTS?---SEEEEE--------EE?S----------S?-EEEEE--------EE----EE---EE?TTHHHHHHHHHHHH 1R6L|A PF03726.9_PNPase_seed 21 91 !Q:0,17|19,23|32,68|83,85|89,90 Q:18,18|24,31|69,82|86,88 ??????????????????S?--??HHHHHHHT????????????---????------????????????HHHHHHHHHHHHTT???SSS?? 3H36|A PF03727.11_Hexokinase_2_seed 15 266 !Q:22,22|27,36|45,46|60,61|71,71|78,78|109,113|115,117|125,125|127,127|136,136|138,138|140,141|152,152|155,158|197,197|208,208|214,214|222,223|231,231|234,238|241,242|248,248|251,251 Q:0,21|23,26|37,44|47,59|62,70|72,77|79,108|114,114|118,124|126,126|128,135|137,137|139,139|142,151|153,154|159,196|198,207|209,213|215,221|224,230|232,233|239,240|243,247|249,250|252,265 TEEEEEEESSSEEEEEEEETTT?TTSS?---------SSSEEEEE??GGGTTTTSTTTTT??HHHHHHHHT-SSSTTS?TTGGGTSTTTHHHHHHHHHHHHHHTTSSGG-----G???TTTSSTT?S?THHHHTTT?T-T??HHHHHHHHHH-TT????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?SSEEEEEEEE?HHHHH?TTHHHHH--HHHHHHH?TT-----EE--EEEEE?SS?HHHHHHHHHHHHHH 3O5B|A PF03728.8_Viral_DNA_Zn_bi_seed 22 138 !Q:1,2|10,13|16,17|20,21|27,27|34,34|38,41|51,51|58,58|61,81|91,93|106,106|109,117|119,122|124,124|128,128|130,137 Q:0,0|3,9|14,15|18,19|22,26|28,33|35,37|42,50|52,57|59,60|82,90|94,105|107,108|118,118|123,123|125,127|129,129 S??STTSSTT????SB-?SS??EEEEE?TTTTSS?GGG??-?HHHHHHHHS?EEEEEE?SS?????????----????????EEEHHHHHH---HHHHHHHHHHTT?SS?--??????B????G-GGS?B???????? 2WB0|X PF03730.9_Ku_C_seed 18 107 !Q:2,5|9,11|28,28|31,36|40,41|48,49|55,56|66,66|69,74|76,106 Q:0,1|6,8|12,27|29,30|37,39|42,47|50,54|57,65|67,68|75,75 TB????TTS???HHHHHHHHHHHHHHTT?SS??????TTS??HHHHHH--HHTTH--HHHHHHHHS?TT?----?S?????-??????--???-----????????? 1JEQ|A PF03731.10_Ku_N_seed 17 288 !Q:7,7|14,15|20,26|47,50|59,59|62,62|65,69|72,73|79,87|90,94|98,99|118,119|126,126|128,132|144,146|150,153|155,156|167,167|169,169|173,177|179,179|190,206|219,220|225,230|233,235|245,258|260,268|283,286 Q:0,6|8,13|16,19|27,46|51,58|60,61|63,64|70,71|74,78|88,89|95,97|100,117|120,125|127,127|133,143|147,149|154,154|157,166|168,168|170,172|178,178|180,189|207,218|221,224|231,232|236,244|259,259|269,282|287,287 EEEEEEE?SSGGGS??SSSS?-----?HHHHHHHHHHHHHHHHHHTT??-?EEEEEEES?SS?BS-----TT??SSEEE---------EE-----EEE??BHHHHHHHHTTSHHHHHH--HHHHHT?S?????HHHHHHHHHHH---HHT--??S??SEEEEEEEES?S?TTS-----S?TTHHHHHHHH-----------------HHHHHHHTEEEE--EEEB----??TT???GGGTGGGTS??????????????B?--------SHHHHHHHHHHHHS????S 1JEQ|A PF03734.9_YkuD_seed 173 406 !Q:7,11|15,15|17,21|24,24|27,28|31,31|35,38|41,41|44,45|48,59|61,86|90,93|95,95|98,112|116,116|118,134|139,139|142,193|195,195|201,201|207,207|212,216|221,221|225,229|233,259|264,267|270,270|274,276|278,304|314,368|371,401|404,405 Q:0,6|12,14|16,16|22,23|25,26|29,30|32,34|39,40|42,43|46,47|60,60|87,89|94,94|96,97|113,115|117,117|135,138|140,141|194,194|196,200|202,206|208,211|217,220|222,224|230,232|260,263|268,269|271,273|277,277|305,313|369,370|402,403 SSEEEEE-----TTT-T-----EE-EE--EE-TTE----EE-EE--EE----------??B?------------------------?TTS????S?EE??-----------??EES?E-----------------EEEE?SS----------------------------------------------------S?EEEEE?SEEEE?SSSS----?EEEE?SSS?--??STT?--------------------------HHHH?--?SS?EEE-?-T---------------------------TTHHHHHHH----------------??-------------------------------------TT-?-----------------------------EE?? 3U1Q|A PF03735.9_ENT_seed 20 94 !Q:4,5|25,25|27,29|41,58|63,64|78,78|90,90|92,93 Q:0,3|6,24|26,26|30,40|59,62|65,77|79,89|91,91 HHHH--HHHHHHHHHHHHHHHHHHH?S-??HHHHHHHHHHH------------------HHTT??HHHHHHHHHHHHH?HHHHHHHHHHH?S?? 2FMM|E PF03737.10_Methyltransf_6_seed 11 186 !Q:0,3|11,11|15,15|18,19|21,22|25,28|31,31|33,33|43,43|46,61|71,72|81,81|84,84|86,95|100,101|114,114|123,124|141,143|145,150|152,153|155,156|159,160|168,169|171,171|179,179|182,182 Q:4,10|12,14|16,17|20,20|23,24|29,30|32,32|34,42|44,45|62,70|73,80|82,83|85,85|96,99|102,113|115,122|125,140|144,144|151,151|154,154|157,158|161,167|170,170|172,178|180,181|183,185 ????HHHHHHH?TTT?EE??S??EE---?SS?S?EEEEEEEEE?SS--------------??HHHHHHHTS??BTEEEEEE?TT?S----------SSBS??HHHHHHHHHTTB?EEEEEEEE??HHHHTTSSSEEEEEEE???B--????S??E--ES??EEETTEE--E?TTSEEEE?SS?EEE 2YJT|A PF03738.9_GSP_synth_seed 159 170 !Q:2,2|7,12|14,14|22,23|34,46|48,48|56,56|60,61|64,77|79,80|82,83|85,85|87,87|91,94|96,97|102,102|105,105|117,117|120,121|123,125|127,130|132,133|136,139|146,146|148,149|151,157|162,162 Q:0,1|3,6|13,13|15,21|24,33|47,47|49,55|57,59|62,63|78,78|81,81|84,84|86,86|88,90|95,95|98,101|103,104|106,116|118,119|122,122|126,126|131,131|134,135|140,145|147,147|150,150|158,161|163,169 EE-EEEE-----?S?HHHHHHH--HHHHHHHHHT-------------T?EEEEEES-STT-?EE?-------------S--S??E-E?TTS---?B??EEEE-SS?HHHHHHHHHHH?SS??S---S????S??TT????HHHHHT?T--T------?EEES?GGGGTTT 2IO9|A PF03740.8_PdxJ_seed 9 276 !Q:0,0|6,6|19,20|22,22|33,33|36,36|43,44|47,47|51,51|62,62|65,70|76,76|78,78|84,90|96,97|103,105|111,111|117,117|120,122|137,137|144,144|146,146|158,158|165,165|185,186|190,191|193,193|220,220|228,229|239,239|242,245|250,250|261,261|274,275 Q:1,5|7,18|21,21|23,32|34,35|37,42|45,46|48,50|52,61|63,64|71,75|77,77|79,83|91,95|98,102|106,110|112,116|118,119|123,136|138,143|145,145|147,157|159,164|166,184|187,189|192,192|194,219|221,227|230,238|240,241|246,249|251,260|262,273 ?EEEEE?HHHHHHHHHHTS??S?HHHHHHHHHH-HS-SEEEEE??TT?SSS?HHHHHHHHHH?SS?-----EEEEE?S?HHHHH-------HHHHH??SEEEE???SGGGB?TTSSB?TT--?TTHHHHHHHHHHTT?EEEEEE?S?HHHHHHHHHTT?SEEEEE?HHHHHHHHHHHSSGGGSTT??GGG-?S?HHHHHHHHHHHHHHHHHHHHHHHHTT?EEEEESS??TTTTHHHHT?TT--??EEEE?HHHHHHHHHH?HHHHHHHHHHHT?? 1IXP|A PF03742.9_PetN_seed 22 29 !Q:0,0|27,28 Q:1,26 ?HHHHHHHHHHHHHHHHHHHHHHHHTT?? 2ZT9|H PF03743.9_TrbI_seed 149 244 !Q:3,3|6,6|15,15|21,29|33,33|38,38|40,40|43,44|48,52|57,57|60,60|67,68|70,75|78,79|82,83|90,90|94,99|102,102|106,108|114,114|117,119|124,124|126,126|129,130|147,150|154,208|220,222|227,227|230,230|232,232|237,238|240,240|243,243 Q:0,2|4,5|7,14|16,20|30,32|34,37|39,39|41,42|45,47|53,56|58,59|61,66|69,69|76,77|80,81|84,89|91,93|100,101|103,105|109,113|115,116|120,123|125,125|127,128|131,146|151,153|209,219|223,226|228,229|231,231|233,236|239,239|241,242 GEE?TT?EEEEEESS?EETTS--------?EEE-EEEE?S?EE-?TTS----?BEEE?TT?EEEEEE-?S?---??TT??EE??EEEEEE?TTT-----?EE-EEE---EEEEE?TT-??BSEE?E-EE??HHHHHHHHHHHHHHHH----HHH??---------????????????????-----------------------?????HHHHHHHHTSS?-?EEEE?TT?E-EEEE??S?EE? 3JQO|A PF03745.9_DUF309_seed 100 72 !Q:0,1|13,13|27,30|32,33|36,37|55,55|60,67 Q:2,12|14,26|31,31|34,35|38,54|56,59|68,71 ??HHHHHHHHHTT?HHHHHHHHHHHHH----H??HH--HHHHHHHHHHHHHHHHH-HHTT??-----?HHHH 2CXD|A PF03746.11_LamB_YcsF_seed 15 247 !Q:8,10|15,16|18,20|28,28|35,35|40,41|57,57|63,65|67,67|73,73|75,79|103,104|109,111|121,121|136,136|139,139|146,148|150,150|161,162|168,168|172,172|174,174|178,178|180,187|189,191|210,210|214,214|218,220|225,227|247,247 Q:0,7|11,14|17,17|21,27|29,34|36,39|42,56|58,62|66,66|68,72|74,74|80,102|105,108|112,120|122,135|137,138|140,145|149,149|151,160|163,167|169,171|173,173|175,177|179,179|188,188|192,209|211,213|215,217|221,224|228,246 EEEEEEEE???BTTB??S?--HHHHTTT?SEEEEE?SSSS??HHHHHHHHHHHHHTT?EEEEE???S?TTTTT?S?????HHHHHHHHHHHHHHHHHHHHHTT??EEEE???HHHHHHHHH?HHHHHHHHHHHHHH?TT?EEEEET---T?HHHHHHHHHT??EEEEE?TTB?B?TTS?B????????B???HHHHHHHHHHHHHHSEEE?TTS?EEE???SEEE???SSHHHHHHHHHHHHHHHHT- 2DFA|A PF03747.9_ADP_ribosyl_GH_seed 176 682 !Q:13,16|18,18|23,27|30,31|34,95|97,99|105,106|108,108|111,122|137,177|182,187|189,189|192,200|205,205|209,219|224,267|273,287|291,293|296,296|298,302|304,311|314,382|385,385|395,395|398,399|403,412|414,414|418,420|423,423|433,435|453,453|457,466|475,510|515,518|532,580|583,584|601,617|620,627|638,641|643,643|662,664|666,669|672,674|676,676|679,680 Q:0,12|17,17|19,22|28,29|32,33|96,96|100,104|107,107|109,110|123,136|178,181|188,188|190,191|201,204|206,208|220,223|268,272|288,290|294,295|297,297|303,303|312,313|383,384|386,394|396,397|400,402|413,413|415,417|421,422|424,432|436,452|454,456|467,474|511,514|519,531|581,582|585,600|618,619|628,637|642,642|644,661|665,665|670,671|675,675|677,678|681,681 HHHHHHHHHHHHH----H-TTTT---??TT--SS?--------?--------------------------------------------------??S???BTTTT--B?TT??-----?----HHHHHHHHHHHHHH-----------------------------------------HHSS-----?H-HH---------HHHH-HHH-----------HHHT???------------------------??????????-----??HHHHH---------------HHH---HH-H??---S???----?TT-------------------------------------------------------------------??BS-GGGGGHHHH-HH--HHT----------T?TTH---HH-HHHHHHHTT???HHHHHHHHHHHHHHHHH-HTT?-----?---HHHHHHTG------------------------------------GGTT????HHHHHHHTTGGGS?-----------------------------------------------?SS??SBHHHHHHHHHHHHHH----------------?SS--------HHHHHHHHHT----T?SSHHHHHHHHHHHHHHHH-?-G----GG---S?HH--H 2CWC|A PF03749.8_SfsA_seed 13 231 !Q:12,12|16,16|22,25|27,28|32,33|36,36|43,43|46,47|50,51|59,59|62,62|64,64|68,69|83,83|86,86|91,92|94,94|103,109|131,131|139,143|146,146|149,150|168,169|178,178|182,183|188,188|192,192|207,208|222,222|229,230 Q:0,11|13,15|17,21|26,26|29,31|34,35|37,42|44,45|48,49|52,58|60,61|63,63|65,67|70,82|84,85|87,90|93,93|95,102|110,130|132,138|144,145|147,148|151,167|170,177|179,181|184,187|189,191|193,206|209,221|223,228 EEEETTTEEEEE?TTS?EEEEE????S??TTT??TT?EEEEEE?SS??SS??EEEEEEE?TT-S?EEE??GGGHHHHHHHHHH-TT?SGGG?-S?SEEEEEEE?????-?EEEEEEEETTEEEEEEEEEEE?EEETTEE-----EE?SS??HHHHHHHHHHHHHHHTT-?EEEEEEEE?BTT??EEEE?TTT?HHHHHHHHHHHHTT-?EEEEEEEEEETTE-EEEEEE?? 4DAP|A PF03759.8_PRONE_seed 16 393 !Q:20,20|25,26|28,29|49,56|77,77|83,96|102,102|129,132|135,172|175,176|179,181|214,216|224,224|226,226|232,232|240,240|242,242|245,246|255,257|279,314|336,336|339,342|352,354|392,392 Q:0,19|21,24|27,27|30,48|57,76|78,82|97,101|103,128|133,134|173,174|177,178|182,213|217,223|225,225|227,231|233,239|241,241|243,244|247,254|258,278|315,335|337,338|343,351|355,391 HHHHHHHHHHHHHHHHHTTT?TTSS??S??HHHHHHHHHHHHHHHHHTT????????HHHHHHHHHHHHHHHGGGGG?EEEEE????????-?????EEEEE?HHHHTHHHHHHHHHHHHHHHHHGGGS????EE????-------------???????-?????????????EE??TT???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS???HHHHHHS?S?HHHHH?HHHHHHH-T?SS??HHHHHHTS???SHHHHHHHHHHHHHHHHHHHH?????----------????--???????--------HHHHHHHHHHHHHHHHHHHHH?TT????HHHHHHHHH???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH? 2NTX|A PF03762.12_VOMI_seed 22 428 !Q:2,3|7,9|13,15|18,18|22,23|32,33|35,35|37,39|42,57|67,67|69,172|174,175|177,178|184,187|190,190|192,192|195,195|204,207|210,217|224,234|238,238|242,242|244,250|254,336|350,412|415,415|417,417|427,427 Q:0,1|4,6|10,12|16,17|19,21|24,31|34,34|36,36|40,41|58,66|68,68|173,173|176,176|179,183|188,189|191,191|193,194|196,203|208,209|218,223|235,237|239,241|243,243|251,253|337,349|413,414|416,416|418,426 EE??SSS???SEE???EE?SSS-?EEEEEEEE??S?S---SS----------??????EEEEEETTS?E--------------------------------------------------------------------------------------------------------E??S??SSSEE?-??EE?S-SS?EEEEEEEE????SS-???????EEEEEE-----------TTS?EEE?S?-???--SEE?????-----------------------------------------------------------------------???----EEEEEEEEESTTS--------------------------------------------------------------?TT-T?EEEEEEEEE? 1VMO|A PF03764.13_EFG_IV_seed 81 136 !Q:0,0|2,2|4,5|9,9|12,12|15,17|22,24|29,30|36,36|41,49|52,53|59,65|67,67|70,70|88,88|93,94|96,96|103,103|107,108|110,111|115,115|135,135 Q:1,1|3,3|6,8|10,11|13,14|18,21|25,28|31,35|37,40|50,51|54,58|66,66|68,69|71,87|89,92|95,95|97,102|104,106|109,109|112,114|116,134 ?E-E??EEE?SS?EE-??EEEE??-SSSS??EEEEE?EEEE??-------TT??EEEEE???----S?SS?TTTHHHHHHHHHHHTTS?TTTS??B?SEEEEE?EEE??T--TTB?HHHHHHTHHHHHHHHHHTS? 1N0V|C PF03765.10_CRAL_TRIO_N_seed 148 94 !Q:6,9|16,16|19,19|22,39|42,42|46,47|54,55|57,59|66,66|68,69|82,82 Q:0,5|10,15|17,18|20,21|40,41|43,45|48,53|56,56|60,65|67,67|70,81|83,93 HHHHHH----HHHHHH?TT?EE------------------ES?STT??TTSEEE??H---HHHHHS?H--HHHHHHHHHTTS?HHHHHHHHHHH 3HY5|A PF03767.9_Acid_phosphat_B_seed 31 354 !Q:0,13|15,15|19,22|25,25|28,30|37,39|42,43|55,55|59,59|79,82|84,92|95,95|101,102|108,110|119,119|121,124|128,130|132,139|142,149|152,152|159,162|164,164|167,168|171,172|183,183|195,196|204,208|215,239|246,247|250,254|259,261|273,274|276,276|279,291|295,299|308,308|310,317|322,340|345,348|350,353 Q:14,14|16,18|23,24|26,27|31,36|40,41|44,54|56,58|60,78|83,83|93,94|96,100|103,107|111,118|120,120|125,127|131,131|140,141|150,151|153,158|163,163|165,166|169,170|173,182|184,194|197,203|209,214|240,245|248,249|255,258|262,272|275,275|277,278|292,294|300,307|309,309|318,321|341,344|349,349 ??????????????S?HHH----HH-HH---HHHTSS???SS??GGGHHHHHHHH-TTT?HHHHHHHHHHHHHHHHHHT????T---------TS?EEEEE??BTTTB-??HHHHGGGG-G----GTS???T--------TH--------HH-HHHHTT????B?HH--HH--HHHHHHHHTT?EEEEEEEEEGG--GHHHHHH-----HHHHTT-----------------??----??SEEEEE?-TT-????HHHH---HHHHHHHHHHT--T?EE-------------EEE-----EESSGGGG?T--------TSSS-------------------EEEE????S???? 3ET5|A PF03770.11_IPK_seed 109 463 !Q:5,5|10,10|13,16|26,26|29,29|40,42|53,53|55,55|58,58|60,60|68,68|70,70|96,138|142,151|154,156|159,161|165,165|177,193|195,195|201,205|221,221|225,225|231,231|233,233|240,240|243,410|417,418|421,421|425,425|429,436|440,442|446,449 Q:0,4|6,9|11,12|17,25|27,28|30,39|43,52|54,54|56,57|59,59|61,67|69,69|71,95|139,141|152,153|157,158|162,164|166,176|194,194|196,200|206,220|222,224|226,230|232,232|234,239|241,242|411,416|419,420|422,424|426,428|437,439|443,445|450,462 EEEEE?TTTT?SS?---EEEEEEESS?SS?HHHHHHHTTS???BHHHHHHHHH-H?TT?S?HHHHHHT?B?HHHHHHHHTTSSSHHHHSEEEEEEE?------------------------------------------TTS---------?EE???TT-??SHH-HHHHHHHHHHT-----------------T?HHHHH-----HHHHHHHHHHHHHTT?HHH-HTEEE?S?EEEEEE?TT----------------------------------------------------------------------------------------------------------------------------------------------------------------------??EEEEEE??TT-EEE?STT??----??SSS???TTS????HHHHHHHHHHHHH 1W2D|A PF03775.11_MinC_C_seed 15 111 !Q:0,0|4,4|6,6|8,8|17,17|19,19|25,25|27,27|30,30|37,37|45,45|51,51|55,55|57,57|59,59|67,68|79,84|87,88|90,96 Q:1,3|5,5|7,7|9,16|18,18|20,24|26,26|28,29|31,36|38,44|46,50|52,54|56,56|58,58|60,66|69,78|85,86|89,89|97,110 ?SEE?S?B?TTEEEEES-S?EEESS?B?TT?EEEESS?EEEEEEE?SEEEE?TTT?T-T?EEEEEEE??SEEEETTEEE????-?TT??E-------EEEEETTEEEEEEG 1HF2|A PF03776.9_MinE_seed 104 84 !Q:22,24|26,29|47,51|53,56|63,63|67,72|78,79|82,83 Q:0,21|25,25|30,46|52,52|57,62|64,66|73,77|80,81 HHHHHHHHHHHHHHHHHHHTTS--?S----SHHHHHHHHTTGGGTTS????-S????EEEEET-TTE------EEEEB??EE?? 1EV0|A PF03781.11_FGE-sulfatase_seed 22 396 !Q:0,1|8,9|15,17|19,33|36,37|39,39|43,45|47,47|53,55|62,63|75,77|79,82|97,108|110,110|118,118|121,126|135,135|145,147|150,150|155,156|158,159|172,211|213,215|227,230|233,233|240,240|246,253|256,258|260,261|266,269|273,276|279,282|285,285|287,287|289,291|295,295|297,297|310,326|333,337|341,344|346,347|355,356|359,360|362,363|366,367|373,375|379,381|384,385|391,393|396,396 Q:2,7|10,14|18,18|34,35|38,38|40,42|46,46|48,52|56,61|64,74|78,78|83,96|109,109|111,117|119,120|127,134|136,144|148,149|151,154|157,157|160,171|212,212|216,226|231,232|234,239|241,245|254,255|259,259|262,265|270,272|277,278|283,284|286,286|288,288|292,294|296,296|298,309|327,332|338,340|345,345|348,354|357,358|361,361|364,365|368,372|376,378|382,383|386,390|394,395 ??TTEEEE??EEEEE---S?--------------SS??S?GGG???S?EEEEE-??EEEESS??BHHHHHHHHHH---H????HHHHHSEEEEEGGG----------??S?GGGEEEE?SS?-----TTEEEEET?BTTBTTSTT???TT?TTSB??S??HHHHHHHHHHHT?---------------------------------------B???HHHHHHHHHTT?---SS?SBTTBS?SSGGG??-----?SB???S--STTT????TTS---?SS-???SS?S?B--?TTS?B?SSBSSEEEEEEE??---------------TTHHHH?---?SBS????S??SSEEEES??TT??T--TT??TTSTT??-EEE--?TT??BTTEE???EE- 2HI8|X PF03784.8_Cyclotide_seed 30 39 !Q:0,2|5,5|14,17|24,25|31,33|38,38 Q:3,4|6,13|18,23|26,30|34,37 ?--EE-EEEETTTS?-?-GGGGGT-?EEETT---EEEE? 2K7G|A PF03785.9_Peptidase_C25_C_seed 3 82 !Q:0,0|2,4|7,8|12,12|15,15|27,27|43,43|45,45|53,53|56,57|60,60|69,69|73,74 Q:1,1|5,6|9,11|13,14|16,26|28,42|44,44|46,52|54,55|58,59|61,68|70,72|75,81 ?B???EE??SEE?TT?SEEEEEESSTT?EEEEEETTEEEEEEE?B-TTEEEEE?SS??TT?SEEEEEEE?TTB??EEEEEEE 4IEF|B PF03786.8_UxuA_seed 10 408 !Q:1,1|6,8|10,10|12,12|15,15|23,23|25,26|31,32|36,36|38,44|47,49|65,65|72,76|83,83|105,106|111,114|116,117|119,120|127,127|131,131|137,137|148,149|152,153|161,161|175,176|190,191|194,194|196,199|213,214|238,238|243,245|250,252|255,258|272,274|292,293|304,305|312,314|318,318|320,320|324,324|328,329|333,334|338,338|358,364|367,371|373,373|378,378|381,382|386,387 Q:0,0|2,5|9,9|11,11|13,14|16,22|24,24|27,30|33,35|37,37|45,46|50,64|66,71|77,82|84,104|107,110|115,115|118,118|121,126|128,130|132,136|138,147|150,151|154,160|162,174|177,189|192,193|195,195|200,212|215,237|239,242|246,249|253,254|259,271|275,291|294,303|306,311|315,317|319,319|321,323|325,327|330,332|335,337|339,357|365,366|372,372|374,377|379,380|383,385|388,407 S?BEEE???T-T?SS?HHHHHHH-T??EEEE??TTS?T-------TS???HHHHHHHHHHHHHTT?EEEEEE?????HHHHHT?TTHHHHHHHHHHHHHHHHHTT??EEEE????S??S??SEEEEE?TTS?EEEEE?HHHHHHHHHH--TS??TTGGGGS?HHHHHHHHHHHHT??HHHHHHHHHHHHS??TT?S????HHHHHHHHHTTTT??HHHHHHHHHHHHHHHHHHHHHHT?EEEE???SSSS?-?TT????SSSHHHHHHHHHH???TTEEEEEEHHHHTTSTT??HHHHHHHHGG--GEEEEE???EEE?S-STT?EEE??TTS--SSS?HHHHHHHHHHHHHHHHHTT????-??EE?????B?GGGG-GS??STT??SHHHHHHHHHHHHHHHHHHH 3FVM|A PF03787.10_RAMPs_seed 154 809 !Q:6,7|10,15|18,123|131,132|134,136|139,139|143,143|148,148|158,162|175,176|188,216|218,219|226,226|235,236|239,239|244,417|424,429|431,479|484,484|487,487|493,493|498,498|501,501|508,508|520,522|524,525|530,531|533,533|535,605|618,618|620,657|660,660|663,721|731,733|752,777|781,781|784,787|789,789|792,798|801,801|804,806 Q:0,5|8,9|16,17|124,130|133,133|137,138|140,142|144,147|149,157|163,174|177,187|217,217|220,225|227,234|237,238|240,243|418,423|430,430|480,483|485,486|488,492|494,497|499,500|502,507|509,519|523,523|526,529|532,532|534,534|606,617|619,619|658,659|661,662|722,730|734,751|778,780|782,783|788,788|790,791|799,800|802,803|807,808 EEEESS?-EE------SS??--------------------------------------------------------------------------------------------------------HHHHHHT??B???EE?TTT?SEEB?HHHHHHHHH-----HHHHHHHHHHTT??HHHHHGGGTTS?-------------------------???S??SHHHHH-HHGGGBSS??TT?BTTB?-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHHHHH-----?B?------------------------------------------------SSTT?TT?HHHHH?TTTS?SS?TTTTTB?GGGHHHHTTTS???B??SEEE??B?B?----------------------------------------------------------------------HHHHHTHHHHHT?S??????????????????--------------??--??EE?TT----------------------------------------------------------?EEEEEEEEE???GGGHHHHHHHHHHHHHHH--------------------------HHH?SE----E?SS-------SE-ES?--EE 4N0L|A PF03793.14_PASTA_seed 237 104 !Q:3,6|9,12|21,21|26,32|35,44|52,60|64,64|68,70|77,83|88,88|91,92|94,95|103,103 Q:0,2|7,8|13,20|22,25|33,34|45,51|61,63|65,67|71,76|84,87|89,90|93,93|96,102 EEE?-??TT----SBHHHHHH-HHHT-------TT?---------EEEEEEE-------??SSS?TTB---EEEEES?------SEEE-ET--T?-EEEEEEE? 2Z2M|C PF03795.9_YCII_seed 26 125 !Q:9,9|17,17|40,40|47,49|53,53|59,59|62,62|69,69|72,73|98,98|104,105|113,113|115,124 Q:0,8|10,16|18,39|41,46|50,52|54,58|60,61|63,68|70,71|74,97|99,103|106,112|114,114 EEEEEEEEE?GGGSSSS?HHHHHHHHHHHHHHHHHHHHHT?EEEEEE???GGG?EEEEE?SS?EEEEES?SS??SSEEEEEEEEEESSHHHHHHHHTT?GGGGG--SEEEEEE?S-------??? 1S7I|A PF03796.10_DnaB_C_seed 36 810 !Q:0,0|2,3|5,5|14,15|18,18|21,21|27,28|32,32|49,62|64,66|75,75|90,98|105,111|129,130|135,136|139,140|155,156|158,160|166,166|171,172|174,188|207,208|214,216|222,229|237,666|672,677|685,685|688,747|753,761|766,767|771,772|774,786|790,794|806,809 Q:1,1|4,4|6,13|16,17|19,20|22,26|29,31|33,48|63,63|67,74|76,89|99,104|112,128|131,134|137,138|141,154|157,157|161,165|167,170|173,173|189,206|209,213|217,221|230,236|667,671|678,684|686,687|748,752|762,765|768,770|773,773|787,789|795,805 ?B??S?HHHHHHHS--SB?TT?EEEEE??TTS?HHHHHHHHHHHHHHHS--------------S-??EEEEESSS?HHHHHHHHHHHHHT?-------?HHHHHH-????--HHHHHHHHHHHHHHHSS?-EEEE??TT??HHHHHHHHHHHHTT--T???EEEEE?GGGS??S?--?????-----??HHHHHHHHHHHHHHHHHT??EEEEE???TTTTT??-?????THHHHTT?---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHHHH-----?SEEEEEE?TT????----------------??????----------------------------------EEEEE---------EEEE--SSS??E-------------EEE-----EEEETTTTEEE???? 4A1F|A PF03797.14_Autotransporter_seed 212 399 !Q:0,3|17,20|22,28|31,36|51,56|59,59|77,98|102,104|119,144|157,158|168,170|172,187|190,192|210,210|213,222|240,241|244,245|248,248|251,258|260,260|265,267|281,281|284,284|288,313|319,319|328,328|331,361|375,375|381,381|387,391|398,398 Q:4,16|21,21|29,30|37,50|57,58|60,76|99,101|105,118|145,156|159,167|171,171|188,189|193,209|211,212|223,239|242,243|246,247|249,250|259,259|261,264|268,280|282,283|285,287|314,318|320,327|329,330|362,374|376,380|382,386|392,397 ????EEEEEEEEEEEEE----E???????EE------EEEEEEEEEEEEEE----??TT-EEEEEEEEEEEEEEEEE--------------------?-SSS???EEEEEEEEEEEEEE--------------------------ESSSEEEEEEEE--EEEEEEEEE???S----------------SS???EEEEEEEEEEEEEEEEE?EE?---------GGGEEEEEEEEEEEEEE??EE--EE?TT--------S?EEEE???EEEEEEEEEEEEE?EE?SSS?-------------------------EEEEE-EEEEEEEE-EE?????????------------??????????EEEEEEEEEEEET-TTEEE-EEEEE-----EEEESS? 3SLO|A PF03799.10_FtsQ_seed 180 220 !Q:6,7|9,12|19,20|24,27|29,42|46,47|50,54|58,58|60,66|69,69|74,80|94,94|97,100|105,105|109,113|118,121|123,127|129,129|131,131|133,133|140,149|153,167|180,191|202,210|214,215 Q:0,5|8,8|13,18|21,23|28,28|43,45|48,49|55,57|59,59|67,68|70,73|81,93|95,96|101,104|106,108|114,117|122,122|128,128|130,130|132,132|134,139|150,152|168,179|192,201|211,213|216,219 EEEETT--T----EEEETT??EEE?--?G--------------GGT--TT?-???EEE?S-------TT?HHHH-------HHHHHHHHHHHHT-TT????EEEE?SSS?----EEEE?---S-----S-S?E-EEEESS-------?--HHH---------------HHHHHHHHHHHH------------HHHHHHTTEE---------EEE--EEEE 2ALJ|A PF03800.9_Nuf2_seed 31 193 !Q:0,13|15,16|27,29|32,33|40,41|49,50|68,70|75,86|88,90|93,95|97,97|100,116|140,145|152,153|176,178 Q:14,14|17,26|30,31|34,39|42,48|51,67|71,74|87,87|91,92|96,96|98,99|117,139|146,151|154,175|179,192 ???-------????S??HHHHHHHHHH---HT??THHHHH??GGGTSSS??HHHHHHHHHHHHHHHHT?-?GGGG------------G???TT???S?GG-----------------GGTTTHHHHHHHHHHHHHHHHTT??-???HHHHHS??HHHHHHHHHHHHHHHHHHHHHH---HHHHHHHHHHHHHT 3IZ0|D PF03801.8_Ndc80_HEC_seed 37 199 !Q:0,46|48,49|51,51|53,56|58,58|78,82|85,87|94,95|98,98|111,111|116,119|122,125|139,139|142,146|182,196|198,198 Q:47,47|50,50|52,52|57,57|59,77|83,84|88,93|96,97|99,110|112,115|120,121|126,138|140,141|147,181|197,197 ----------------------??-----------------------S??S?T----T?HHHHHHHHHHHHHHHHHTT?----SS???TTTTSS??HH-HHHHHHHHHHHT-TSTT????SS---?HHHHHHHHHHHTT?SS--???HHHHHSTTSTTTHHHHHHHHHHHHHHHHHHHHHTT????--?????????B? 3IZ0|C PF03807.12_F420_oxidored_seed 56 123 !Q:23,30|36,36|48,48|55,61|63,63|65,66|78,79|81,81|87,87|89,89|101,107|119,122 Q:0,22|31,35|37,47|49,54|62,62|64,64|67,77|80,80|82,86|88,88|90,100|108,118 EEEEETTTSHHHHHHHHHHHHTT-------?EEEEE-ESSHHHHHHHH-HHHHHH-------H?S??EEEEEHHHHHH--H?SEEEE?S?GGGHHHHHHHT-------HHHHTTSEEEE???? 3QSG|A PF03810.14_IBN_N_seed 52 95 !Q:11,11|25,27|31,31|36,38|50,51|53,55|62,67|77,77|94,95 Q:0,10|12,24|28,30|32,35|39,49|52,52|56,61|68,76|78,93 HHHHHHHHHHH?HHHHHHHHHHHHH?--TTS?HHHH---HHHHHHHHTTT??S---SHHHHH------HHHHHHHTS?TTHHHHHHHHHTTTTT?- 4HAV|C PF03813.9_Nrap_seed 26 1233 !Q:5,6|8,10|13,13|15,16|24,25|29,30|77,77|80,80|88,100|105,108|117,118|123,123|132,133|135,156|168,168|182,185|187,187|206,207|210,211|215,215|217,217|219,219|235,238|240,245|250,250|254,254|257,258|274,275|279,279|284,298|304,306|309,310|317,318|324,325|345,345|349,350|357,359|362,362|375,377|387,387|390,392|405,410|425,429|440,440|444,446|449,449|455,458|466,466|476,476|478,478|483,483|491,494|497,498|517,517|521,521|528,537|541,541|556,561|564,564|568,569|580,581|587,594|599,599|602,603|623,627|630,630|637,637|644,645|648,650|653,667|673,673|682,684|688,688|713,713|715,715|724,729|733,736|743,743|747,747|755,755|768,775|778,778|783,783|814,814|833,835|840,841|856,856|860,863|879,880|884,885|888,924|941,941|943,943|947,948|951,957|960,960|963,965|969,969|973,977|980,981|997,997|1002,1005|1008,1008|1010,1021|1032,1035|1037,1037|1045,1045|1048,1049|1056,1094|1105,1105|1120,1123|1131,1131|1133,1133|1143,1143|1152,1153|1159,1159|1162,1163|1166,1167|1169,1169|1175,1196|1198,1198|1204,1206|1228,1232 Q:0,4|7,7|11,12|14,14|17,23|26,28|31,76|78,79|81,87|101,104|109,116|119,122|124,131|134,134|157,167|169,181|186,186|188,205|208,209|212,214|216,216|218,218|220,234|239,239|246,249|251,253|255,256|259,273|276,278|280,283|299,303|307,308|311,316|319,323|326,344|346,348|351,356|360,361|363,374|378,386|388,389|393,404|411,424|430,439|441,443|447,448|450,454|459,465|467,475|477,477|479,482|484,490|495,496|499,516|518,520|522,527|538,540|542,555|562,563|565,567|570,579|582,586|595,598|600,601|604,622|628,629|631,636|638,643|646,647|651,652|668,672|674,681|685,687|689,712|714,714|716,723|730,732|737,742|744,746|748,754|756,767|776,777|779,782|784,813|815,832|836,839|842,855|857,859|864,878|881,883|886,887|925,940|942,942|944,946|949,950|958,959|961,962|966,968|970,972|978,979|982,996|998,1001|1006,1007|1009,1009|1022,1031|1036,1036|1038,1044|1046,1047|1050,1055|1095,1104|1106,1119|1124,1130|1132,1132|1134,1142|1144,1151|1154,1158|1160,1161|1164,1165|1168,1168|1170,1174|1197,1197|1199,1203|1207,1227 HHHTT??B?-?TT?E--EEEEEEE??GGG??TTTTSTTHHHHHHHHHHHHHHHHHHHHHHHTTGGGTEEEEEEEGGG?TT?EEEEEEE?????????????GGGT----EEEEEEEE??TTSS?GGGGSTTS??S???????--------???????HHHHHHHHHTT?HHHHHHHHHHHHH----H?TTHHHHHHHHHHHHHHTT??SS??TTT?S?S?SHHHHHHHHHHHTTB----B------STTS?BSS?TT??HHHHHHHHHHHHHHS??SSS?EEEE???????---?????BEEES???SS??EEETTT??BTTTT??HHHHHHHHHHHHHHHHHHT?SSS??HHHHHT???SS?HHHHSSEEEEEE???BSGGGHHHH?SS???HHHHHHHSSHHH------HHHHHHHHHHHHHH-----GGGEEEEEEE-EET???EE?TTSSS????GGGBSSS?SEEEEEEEE?T-TTTT?SEEEEEE?--?SS??HHHHHHHHHHGGGEEEEE?TTS?EEEEEE?---??---?SSS?HHHHHHHHHHHHHT-----?TT?EEE-?HHHHHHHHTS??BSSTT--------GGGS?TT??HHHHHHHHHHHHHHHHHHT??--?SS?EEEEEE?SGGGGT??SS???TT--------------?TTSTT?EEEEEEEE???TTS?SSHHHHHHHHHHHHHHHHHHHHHH?T-TSEEEEEE???---STT????EEEEEE?TTS?EEEEEEE?TTHHHHHHHHHH--------HS?TTTH-HHHHHHHHHHHHHHTHHHHHHHHHHHHHTT?TTHHHHHHHHHHHHHHTT?--TTTS-?HHHHHHHHHHHHHS?TTS????SHHHHHHHHHHHHHH??TTT??EE?????????????????????????????????????HHHHHHHHHHHHHHHH-H?TTS--SS---????EE?SS?--TTS?TTT-----TT??HHHHHHHHHHHHHHH-HHHH----HH?S------------SHHHHHHHTS????S?SEEEEEE?SS??TTTTTB--------------?????????--????????----??SSGGGGGGGS?HHHHHHHHHHHHHT----TTEEEEE?S?HHHHSTTTT?EEEEEEEE?-GGGSS?EE??TT??S?EEESS----------------------S-SEEEE--?HHHHHHHHHHHHGGGEEEEEE----? 4M5D|A PF03815.14_LCCL_seed 68 163 !Q:0,1|3,4|9,26|35,35|37,41|45,49|55,76|95,112|115,115|124,125|127,127|129,131|133,134|136,140|143,143|146,148|150,153|155,155|157,158|160,160 Q:2,2|5,8|27,34|36,36|42,44|50,54|77,94|113,114|116,123|126,126|128,128|132,132|135,135|141,142|144,145|149,149|154,154|156,156|159,159|161,162 ??S??BTTT??----------------SSEEEEEE?S??--?TTS---??EESSS----------------------SEETTSBHHHHHHHHTSS-----------------?TT?EEEEEEEE??B?S???E--E----?SS?EE---E??--S?B--S?EE 1JBI|A PF03816.9_LytR_cpsA_psr_seed 37 248 !Q:0,1|22,22|28,62|66,66|72,90|104,104|106,108|114,114|127,204|211,228|246,247 Q:2,21|23,27|63,65|67,71|91,103|105,105|109,113|115,126|205,210|229,245 ??SEEEEEEEEGGGTEEEEEEE?TTBEE???-----------??-------????------??EES?TTTTT------------------?HHHHHHHHHHHHT-S???EEEEE?HHHHHHHHHHHT--??????????????????--???-----------------------------------------???????????-HHHHHH???????????-----??SHHHHHHHHHHHHHHTT?? 4DE9|A PF03819.12_MazG_seed 54 98 !Q:0,1|21,21|24,33|35,35|38,48|71,72|76,77|92,97 Q:2,20|22,23|34,34|36,37|49,70|73,75|78,91 ??HHHHHHHHHHHHHHHHHHH-HT----------T?HH-----------HHHHHHHHHHHHHHHHHHHHHT--TTS??HHHHHHHHHHHHHT?????? 2GTA|A PF03822.9_NAF_seed 71 73 !Q:0,1|4,7|13,13|16,16|20,20|26,26|28,31|33,39|44,44|46,46|60,61|65,65|69,70 Q:2,3|8,12|14,15|17,19|21,25|27,27|32,32|40,43|45,45|47,59|62,64|66,68|71,72 ??EE--??HHHHH-TT?TTT?GGGGG?S???-S????--?EEEE?S?HHHHHHHHHHHHH--HTT-EEE--EE 2ZFD|B PF03828.14_PAP_assoc_seed 112 101 !Q:0,0|14,14|16,27|29,30|35,35|37,37|39,42|45,45|48,53|56,56|61,88|91,91|94,94|100,100 Q:1,13|15,15|28,28|31,34|36,36|38,38|43,44|46,47|54,55|57,60|89,90|92,93|95,99 ?HHHHHHHHHHHHH-H------------T??TTTB?B?S----SS-TT?---??BH-HHHT???????---------????????????SS?BB?SSSTT? 2Q0E|A PF03829.8_PTSIIA_gutA_seed 35 138 !Q:1,9|17,17|21,22|26,28|31,32|36,36|39,41|53,53|55,55|58,60|63,66|69,69|84,84|95,96|101,105|110,110|119,122|124,129|132,134 Q:0,0|10,16|18,20|23,25|29,30|33,35|37,38|42,52|54,54|56,57|61,62|67,68|70,83|85,94|97,100|106,109|111,118|123,123|130,131|135,137 E---------EEEEEEE?TTT??TTS?--EE--EEE?TT?-?HHHHTTSEEEE?T-TG---GG????TT?EEEETTEEEEEEEE?TTHHHHHHHH??EEEE???-?SSGS?TTEEEEES---?S-?????TT?--EEE 2F9H|A PF03830.10_PTSIIB_sorb_seed 122 174 !Q:12,12|25,25|32,32|37,39|41,41|52,54|57,57|63,63|73,73|76,76|80,80|100,106|109,110|116,119|121,124|129,129|131,132|134,134|136,136|139,139|153,153|155,155|157,157|161,161|167,168|170,172 Q:0,11|13,24|26,31|33,36|40,40|42,51|55,56|58,62|64,72|74,75|77,79|81,99|107,108|111,115|120,120|125,128|130,130|133,133|135,135|137,138|140,152|154,154|156,156|158,160|162,166|169,169|173,173 EEEEEEEETTSS?TTHHHHHHHHTT?SEEEEE?HHHH---T?HHHHHHHHHT?-?TT?EEEEE?HHHHHHHHT?GG-GTT?EEEEEESSHHHHHHHHHTT?----??SE--EEEEE????T----TSEE?S--S-S?EE?HHHHHHHHHHHHT-T?E-EEE?SSTTS??E---E 2JZH|A PF03831.9_PhnA_seed 104 68 !Q:1,1|3,3|7,7|9,10|13,13|17,18|20,20|23,23|28,28|30,30|32,32|35,35|40,40|43,46|48,50|54,54|58,60|64,66 Q:0,0|2,2|4,6|8,8|11,12|14,16|19,19|21,22|24,27|29,29|31,31|33,34|36,39|41,42|47,47|51,53|55,57|61,63|67,67 S?B?TTS?B??TT?EEE??S?EE?SSSS?E-E?TT?EEES?EE---?S---STT?EEE---EET---T 2AKL|A PF03833.8_PolC_DP2_seed 6 967 !Q:0,38|48,49|61,61|65,65|83,85|88,89|109,109|125,125|130,131|139,139|146,146|166,172|191,193|196,198|209,209|216,218|220,223|225,225|227,229|232,234|238,238|265,266|268,268|282,966 Q:39,47|50,60|62,64|66,82|86,87|90,108|110,124|126,129|132,138|140,145|147,165|173,190|194,195|199,208|210,215|219,219|224,224|226,226|230,231|235,237|239,264|267,267|269,281 ???????????????????????????????????????HHHHHHHHH??TTHHHHHHHHH-HHH?HHHHHHHHHHHHHHTTT???SS--HHHHHHHHHHHHHHHHTTT?SSIIIIIEEEEEEEE?TTTT??EEEEEEE?GGGGGS?HHHHHHHHHHHHHHHHHTT???????HHHHHHHHHHHHHHHHHT???SS???HHHHHHHHHH?SSEEEE???B????S-S???TT???SSB?HHHHHHHHTTTTTTHHHHHHHHHHHT??S?HHHHHHHHHHHHT?---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------????-------------------------------------???----------------------------------------------------------------------------????----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3O59|X PF03834.9_Rad10_seed 26 77 !Q:5,5|11,11|17,20|23,23|27,35|58,58|72,72|74,74 Q:0,4|6,10|12,16|21,22|24,26|36,57|59,71|73,73|75,76 SSEEE?GGGTT?HHHHH--??SS?EEE-?-?----?SSSEEEETTEEEEEEEHHHHHH?SHHHHHHHHHHHH-H?SE 2JPD|A PF03835.10_Rad4_seed 41 244 !Q:2,6|9,11|13,35|46,46|54,56|59,74|88,88|92,97|100,101|105,106|108,108|115,120|125,125|129,129|133,133|138,138|140,141|154,166|176,181|187,191|194,195|197,199|201,233 Q:0,1|7,8|12,12|36,45|47,53|57,58|75,87|89,91|98,99|102,104|107,107|109,114|121,124|126,128|130,132|134,137|139,139|142,153|167,175|182,186|192,193|196,196|200,200|234,243 EE?????TT???S????-----------------??TTHHHHHTTS?SEEEEEE---ET----------------TTTEEEEEESSSS?EEE??----SS??TTS??S-TTGGGT??-???EEEE?TTS?EEE?HHHH?T--TTTTTGGGGSGG-------------GSHHHHHHH------HHHHH-----HH??S???H---------------------------------HHHHHHHHHH 2QSH|A PF03838.9_RecU_seed 43 175 !Q:0,3|22,22|27,54|57,57|77,77|87,87|102,102|132,132|136,137|146,150|157,158|160,160|166,166 Q:4,21|23,26|55,56|58,76|78,86|88,101|103,131|133,135|138,145|151,156|159,159|161,165|167,174 ????SHHHHHHHHHHHHHHTTS?EEEE????????????????????????????SS?SEEEEETTEEEEEEEEEES?SSEEEGGGS?HHHHHHHHHHHHTT?EEEEEEEETTTTEEEEEEHHHHHHHHHHH-TTT??SEEEHHHH-----HHHSEE??B?SSSSB?HHHHHHHH 2FCO|A PF03840.9_SecG_seed 183 83 !Q:0,6|26,27|34,34|36,37|39,40|42,46|49,57|73,73|79,82 Q:7,25|28,33|35,35|38,38|41,41|47,48|58,72|74,78 ???????HHHHHHHHHHHHHHHHHHH--HHHHTT-T??S--S?????SS-?????---TTHHHHHHHHHHHHH-HHHHH???? 3DIN|E PF03841.8_SelA_seed 11 379 !Q:3,3|5,6|9,9|16,22|36,36|38,38|41,41|48,50|64,65|73,73|86,86|97,99|116,116|123,123|126,128|136,137|147,149|157,161|174,175|183,185|187,187|193,199|208,208|220,220|224,224|230,230|240,240|248,249|265,266|269,269|281,282|303,305|316,317|322,322|325,326|340,346|360,360|363,363|377,378 Q:0,2|4,4|7,8|10,15|23,35|37,37|39,40|42,47|51,63|66,72|74,85|87,96|100,115|117,122|124,125|129,135|138,146|150,156|162,173|176,182|186,186|188,192|200,207|209,219|221,223|225,229|231,239|241,247|250,264|267,268|270,280|283,302|306,315|318,321|323,324|327,339|347,359|361,362|364,376 EEE?S??SB?TTTTSS???----HHHHHHHHHHHHS?B?TT?BTTTTB???STHHHHHHHHHHH??SEEEEES?HHHHHHHHHHHH?TTSEEEEETT???EETTTEEHHHHHHHHT?EEEEES?SS???HHHHHTT??TTEEEEEEE???SEEEEES?????HHHHHHHHHHHT??EEEEEES???S?GGGGT???????HHHHHTTT?SEEEEESSSTT?SSS?EEEEE?HHHHHHHHT?GGGGTTB??HHHHHHHHHHHHHHH--TT?GGGSHHHHHHS??HHHHHHHHHHHHHHHTTSTT---EEEEEEEEEE??BSSS?TT??EEEEEEEEEESSS------?HHHHHHHHHSSSS?EE?EEETTEEEEEGGG?? 2AEV|A PF03847.8_TFIID_20kDa_seed 8 73 !Q:0,0|12,17|20,23|54,55|58,58|71,72 Q:1,11|18,19|24,53|56,57|59,70 ?HHHHHHHHHHH-----?SS????HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??EE?HHHHHHHHHHHT?? 1H3O|B PF03848.9_TehB_seed 6 193 !Q:13,18|29,29|31,31|38,38|41,41|52,52|60,60|76,78|84,85|89,92|94,94|101,101|108,108|136,137|141,142|145,146|148,149|151,151|169,170|178,178|181,182 Q:0,12|19,28|30,30|32,37|39,40|42,51|53,59|61,75|79,83|86,88|93,93|95,100|102,107|109,135|138,140|143,144|147,147|150,150|152,168|171,177|179,180|183,192 EEEEGGGHHHHHH??????HHHHHHHHHS?S?EEEEES?TT?HHHHHHHHTT?EEEEEES?HHHHHHHHHHHHHTT??-EEEEE??GGG????S?EEEEEE?SSGGGS?GGGHHHHHHHHHHTEEEEEEEEEEEEB??SSS??SS??S??B?TTHHHHHTTTSEEEEEE??EEEEEEE?SS??EEEEEEEEEE 2I6G|A PF03851.9_UvdE_seed 6 313 !Q:5,6|10,13|15,25|29,56|58,60|86,87|91,92|104,107|112,113|130,130|135,137|140,141|144,144|169,171|173,178|183,186|189,189|205,205|216,217|221,222|234,236|248,253|256,257|264,267|273,273|276,280|285,286|288,288|292,292|295,295|297,297|300,301|312,312 Q:0,4|7,9|14,14|26,28|57,57|61,85|88,90|93,103|108,111|114,129|131,134|138,139|142,143|145,168|172,172|179,182|187,188|190,204|206,215|218,220|223,233|237,247|254,255|258,263|268,272|274,275|281,284|287,287|289,291|293,294|296,296|298,299|302,311 EEEES??TTT-???S???------??GGG??--------------------------H---HHHHHHHHHHHHHHHHHHHHHHHTT??EEE??TTSSTTTTSTT????HHHH--THHHHHHHHHHHHHTT?EEEE???TT??TT?SSHHHHHHHHHHHHHHHHHHHHHT???E------EEEE????TT?HHHHHHHHHHHHTTS?HHHHTTEEEE??SSS??HHHHHHHHHHH???EEEEHHHHHHS-----?SS??HHHHHH----HHHTT?SS?---?EEEE??B?TTS?TT?B?SS??HHHHHHHHHH? 3C0L|A PF03852.10_Vsr_seed 7 84 !Q:0,1|4,4|6,8|17,17|19,20|24,24|39,41|44,45|51,57|72,72|78,78|83,83 Q:2,3|5,5|9,16|18,18|21,23|25,38|42,43|46,50|58,71|73,77|79,82 ??SS?H---HHHHHHHH-T??SSS?HHHHHHHHHHHHTT???EE??TTSTT-----??SEEEGGGTEEEEEE?TTTTT?SSTT? 1ODG|A PF03853.10_YjeF_N_seed 82 303 !Q:14,14|22,42|46,46|53,53|56,61|75,76|83,83|87,96|99,100|102,104|106,107|122,130|135,136|143,167|175,176|178,194|196,198|200,202|204,206|208,212|218,222|224,225|231,239|241,241|248,248|252,254|257,257|259,260|263,276|279,290|299,300 Q:0,13|15,21|43,45|47,52|54,55|62,74|77,82|84,86|97,98|101,101|105,105|108,121|131,134|137,142|168,174|177,177|195,195|199,199|203,203|207,207|213,217|223,223|226,230|240,240|242,247|249,251|255,256|258,258|261,262|277,278|291,298|301,302 HHHHHHHHHHHHHH-HHHHHHS--------------------?GGG?EEEEEE?SS------HHHHHHHHHHHHH--TTTSSE-EEE----------EE??S---S??HHHHHHHHHHHHTT-------??EESS??GGGGGG------------------------?SEEEEES??T-----------------T??-S???H---H-----HHHHH-----H--HHHHS-------??E-EEEESS?TTB--?TT-T??BS--------------SS?-------??-?SEEEEESS??HH 3RTB|A PF03854.9_zf-P11_seed 3 50 !Q:0,1|4,5|8,8|10,11|17,17|20,20|44,49 Q:2,3|6,7|9,9|12,16|18,19|21,43 ??SS??SS?S??SSEEE?SS?EEEHHHHHHTTTTSSEETTTTEE?????? 2M1S|A PF03860.11_DUF326_seed 20 27 !Q:9,12 Q:0,8|13,26 THHHHHHHH----HHHHHHHHHHHHHH 3KAV|A PF03861.9_ANTAR_seed 179 68 !Q:3,3|13,20|33,33|35,40|57,58 Q:0,2|4,12|21,32|34,34|41,56|59,67 HHH?HHHHHHHHH--------HHHHHHHHHHHH-S?--??-HHHHHHHHHHHHHHHT??HHHHHHHHH 1SD5|A PF03864.10_Phage_cap_E_seed 77 483 !Q:0,1|11,11|13,14|19,21|27,28|31,31|33,34|38,38|40,42|51,51|53,53|57,60|70,70|73,75|79,79|86,91|93,94|98,99|103,108|110,110|112,113|115,122|134,134|140,141|144,146|150,150|171,171|174,176|178,180|184,185|190,195|201,203|209,211|216,216|220,223|233,238|244,246|251,251|261,263|269,271|273,273|275,279|282,282|291,303|305,305|310,310|317,329|338,339|341,342|344,344|346,346|348,364|366,369|373,376|379,386|394,394|396,402|404,407|412,418|426,427|429,441|443,443|450,451|453,453|456,457|465,465|470,470|472,472|476,476|479,479|482,482 Q:2,10|12,12|15,18|22,26|29,30|32,32|35,37|39,39|43,50|52,52|54,56|61,69|71,72|76,78|80,85|92,92|95,97|100,102|109,109|111,111|114,114|123,133|135,139|142,143|147,149|151,170|172,173|177,177|181,183|186,189|196,200|204,208|212,215|217,219|224,232|239,243|247,250|252,260|264,268|272,272|274,274|280,281|283,290|304,304|306,309|311,316|330,337|340,340|343,343|345,345|347,347|365,365|370,372|377,378|387,393|395,395|403,403|408,411|419,425|428,428|442,442|444,449|452,452|454,455|458,464|466,469|471,471|473,475|477,478|480,481 ??HHHHHHHHT?S??HHHH???HHHHH--HS?E--EEE?S---SSSEEGGG?S?TTS???-EEEEEEETT-EE?--GGG?EEESEE???--?B??EEE??TTS?-????S-S??G--------GGGGSHHHHHH-HHHHH--HH---HHH-HHHHHHHHHHHHHHHHHHSE-EE---E?-?TTS??EEEE?--???GGGEE---EGGGS-??GGGS?TTT--??THHHHHHHH------HTTSS???EEEE?HHHHHHHHT--?HHHHH---H?B??--?SS?SHHHHHHT-------------T?TTTE-EEEEEE-------------TTEEEEEE??E--E-E?T-----------------T?--?EEE----SS?-------TTEEEEE?T-------T-???EEEE????--?HHHHHTT??S------------?S?EEEEEE??S-SS??EEEEEEB?EEEE?S?GGG?EE-EE? 3BQW|A PF03865.8_ShlB_seed 2 404 !Q:0,0|9,10|13,13|16,16|18,19|31,31|33,33|45,45|60,61|63,63|72,72|76,76|79,79|90,90|96,96|105,106|108,109|112,112|141,143|148,152|169,170|190,191|195,197|214,214|221,221|229,248|252,252|257,258|282,282|285,285|292,293|295,300|303,306|308,309|312,312|315,316|327,328|331,331|348,349|353,353|364,365|378,378|380,383|385,385|389,392|403,403 Q:1,8|11,12|14,15|17,17|20,30|32,32|34,44|46,59|62,62|64,71|73,75|77,78|80,89|91,95|97,104|107,107|110,111|113,140|144,147|153,168|171,189|192,194|198,213|215,220|222,228|249,251|253,256|259,281|283,284|286,291|294,294|301,302|307,307|310,311|313,314|317,326|329,330|332,347|350,352|354,363|366,377|379,379|384,384|386,388|393,402 -HHHHHHHS--TT?TT?B??HHHHHHHHHHH?S-SSEEEEEEEEE?SSTTEEEEEEEEEE??S?EEEEEEEE?SSS?SS?EEEEEEEEEE?SSSSS?EEEEEEEE??S??SS?EEEEEEEEEEEEETTEEEEEEEEEEEEE???SSSS?????EEEEEEEEEEEEEEEE??SSEEEEEEEEEEEEEEEEE??TTS???EEEEEEEEEEEEEEEE?SSEEEE-EEEEEEE????????????????????EEE-EEEE--EEEEEEEETTEEEEEEEEEEEEE?SS?SSSSEE??S??????TT????S??SS?SS??EESEEEEEEE??SS?EEEEEEEEEEEESSSS??EEE-EEEEEEEEEE??SSEEEEEEEEEE?S?---S?SSS????SEEEEEEEEE? 3NJT|A PF03868.10_Ribosomal_L6e_N_seed 19 69 !Q:0,3|6,14|18,19|22,24|28,30|40,49|51,55|58,58|63,63|67,68 Q:4,5|15,17|20,21|25,27|31,39|50,50|56,57|59,62|64,66 ????SS?????????TTS??SS???SSS???SHHHHHHHH?---??????S????-SS?SSSS?SSS?? 3J39|E PF03869.9_Arc_seed 3 50 !Q:1,4|10,11|28,28|49,49 Q:0,0|5,9|12,27|29,48 S????EEEEE??HHHHHHHHHHHHHHTS?HHHHHHHHHHHHGGGTGGGG? 1B28|A PF03870.10_RNA_pol_Rpb8_seed 7 152 !Q:10,13|29,31|39,39|47,49|54,54|56,60|69,73|77,78|85,86|95,95|100,101|104,105|110,111|113,113|117,117|132,132|138,139 Q:0,9|14,28|32,38|40,46|50,53|55,55|61,68|74,76|79,84|87,94|96,99|102,103|106,109|112,112|114,116|118,131|133,137|140,151 EEEEEEEEEE????SSTTEEEEEEEESSS?-?EEEEEEE?TTSSSTT???EEEE?S???-?SSSSSTTT----?SSS--TTSTTS-?TTTTSEEE?EEEE??SS??SSSS??S-SEE-EEEEETTEEEEEEE?HHHHT??STTSTTSEEEEE 1K83|H PF03871.9_RNA_pol_Rpb5_N_seed 36 138 !Q:0,2|5,9|15,15|34,38|44,45|55,55|59,70|72,72|77,77|81,81|83,83|89,101|103,103|106,108|114,118|120,120|124,124|134,134 Q:3,4|10,14|16,33|39,43|46,54|56,58|71,71|73,76|78,80|82,82|84,88|102,102|104,105|109,113|119,119|121,123|125,133|135,137 ???HH-----HHHHH-HHHHHHHHHHHHHHHHTB??--?HHHHT??HHHHHHHHB?TTS-----------?B?GGGT?EEE?B?HHHHT-------------T?TT???EEEEE?----S?SEE?HHHHHHHHH-HHH 1K83|E PF03872.8_RseA_N_seed 35 121 !Q:0,1|3,4|15,17|19,21|30,30|50,56|62,62|74,120 Q:2,2|5,14|18,18|22,29|31,49|57,61|63,73 ??H--HHHHHHHTTS???H---HHHHHHHT?HHHHHHHHHHHHHHHHHHT???----SEEES?HHHHHHHHHHT??????-------------?----------????????????????? 1OR7|C PF03873.8_RseA_C_seed 40 72 !Q:0,2|6,6|9,9|12,12|15,52|60,61 Q:3,5|7,8|10,11|13,14|53,59|62,71 ???GGG?SS?TT?TT?????---------????----??????????-?????HHHHHHH--HHHHHHHHHH 3M4W|E PF03874.11_RNA_pol_Rpb4_seed 88 287 !Q:2,2|18,18|27,70|87,87|89,90|95,96|101,101|105,106|108,129|131,135|139,163|173,178|181,192|203,204|217,217|220,255|258,268|270,272 Q:0,1|3,17|19,26|71,86|88,88|91,94|97,100|102,104|107,107|130,130|136,138|164,172|179,180|193,202|205,216|218,219|256,257|269,269|273,286 EE?TTTHHHHHHHHHHHH-HHHTTSSS????????????????????????????????????????????TTHHHHHHHHHHHHHS?S??HHHH--HHHH-HHH--H----------------------S?????TTH-------------------------HHHHHHHHT------TS?--------?-?TTHHHHHHHS??SSHHHHHHHSTT?TT------------------------------------SS----------?H---HHHHHHHHHHHHHS 2B8K|D PF03876.12_SHS2_Rpb7-N_seed 145 197 !Q:6,6|8,8|13,53|55,56|63,69|79,96|101,106|108,108|110,119|128,129|132,147|149,171|173,177|180,183|197,197 Q:0,5|7,7|9,12|54,54|57,62|70,78|97,100|107,107|109,109|120,127|130,131|148,148|172,172|178,179|184,196 EEEEEE?G-GGTT-----------------------------------------S-?HHHHHH-------HHHHHHHTT?-----------------EETT------T-E----------EEEEEEEE--EE----------------E??--------------------?B?--?-TT?--?SEEEEEEEEEEEE- 2B8K|G PF03880.10_DbpA_seed 173 80 !Q:0,0|6,14|26,26|28,29|31,31|40,40|43,43|49,49|52,53|63,64|66,75|79,79 Q:1,5|15,25|27,27|30,30|32,39|41,42|44,48|50,51|54,62|65,65|76,78 ?EEEES?????????HHHHHHHHTST-T??G-GGEEEEEE?SS?EEEEE?TT-?HHHHHHHHT--T????-?????EEE? 2G0C|A PF03881.9_Fructosamin_kin_seed 35 356 !Q:15,19|25,26|37,44|48,48|57,58|83,85|92,93|98,109|115,123|140,150|155,155|158,158|167,170|173,173|195,201|203,203|216,231|234,238|242,242|245,245|256,256|258,267|271,271|273,275|279,279|292,294|306,311|338,338|352,352|355,355 Q:0,14|20,24|27,36|45,47|49,56|59,82|86,91|94,97|110,114|124,139|151,154|156,157|159,166|171,172|174,194|202,202|204,215|232,233|239,241|243,244|246,255|257,257|268,270|272,272|276,278|280,291|295,305|312,337|339,351|353,354 HHHHHHHHHHHHHSS?????EEEEE??SSSSEEEEEE--------SSS?EEEEEEEE--GGGHHHHHHHHHHHHHHHHTTSSB???EEEEEE?-SSEE------------EEEEE?????-???TTHHHHHHHHHHHHHH-------????SSBB?SS?EEETTEEE????BS?HHHHHHHHTHHHHHHHHHHHT?-?---?S?HHHHHHHHHHHH----------------TT?????EEE?SS?SGGGEEEETT-E----------EEE?S???EEE?THHHHHHHTTSS???HHHHHHHHHHS???---TTHHHHHHHHHHHHHHHHHHHHTTTT?HHHHHHHHHHHHH-HT? 3F7W|A PF03882.9_KicB_seed 3 449 !Q:0,12|24,25|29,29|44,50|68,70|96,96|108,108|121,125|150,151|153,156|254,254|300,300|303,304|320,320|327,330|334,448 Q:13,23|26,28|30,43|51,67|71,95|97,107|109,120|126,149|152,152|157,253|255,299|301,302|305,319|321,326|331,333 ???????-----?THHHHHHHHTT??EEE?HHHHHHHHHHHHHT???????EEHHHHHHHHHHHHHHT???STTHHHHHHHHHHHHHHTTSEEEEE?TTSTTSEEEEE?HHHHHHHHHTTS?????HHHHHHHHHHHHHHHHHHHHHHHH??S----HHHHHHTTHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSS?GGGTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTT?TT??HHHHHHHHHHTGGGS?EEEEEE????EEE??????????????????????????????????????????????????????????????????????????????????????????????????????????????????? 3EUJ|B PF03884.9_DUF329_seed 121 75 !Q:0,2|4,11|14,14|18,19|23,23|28,28|30,32|46,46|52,55|59,64|68,68|70,70|73,73 Q:3,3|12,13|15,17|20,22|24,27|29,29|33,45|47,51|56,58|65,67|69,69|71,72|74,74 ?--E--------EE?TTT??EEE?SSSS-S?-?SSSSHHHHHHHHS?SSSSS????SSS??----SSS?S?SS?S 1LV3|A PF03885.8_DUF327_seed 51 180 !Q:0,41|47,47|57,67|88,89|117,129|150,151|158,159|179,179 Q:42,46|48,56|68,87|90,116|130,149|152,157|160,178 ????------------??????-????????????-??--??HHHHH-HHHHHHHHH-----------HHHHHHHHHHHHHHHHHHHH??HHHHHHHHHHHHHHHHHHHHHHHHHHT????----????-HHHHHHHHHHHHHHHHHHHH--HHHSSS??HHHHHHHHHHHHHHHHHHH? 2QUP|A PF03886.8_DUF330_seed 95 213 !Q:1,18|22,26|32,34|36,37|45,45|50,51|55,57|60,60|68,68|87,87|92,108|115,116|124,124|130,130|138,139|145,147|150,156|159,159|161,168|175,175|182,182|186,186|188,191|204,204 Q:0,0|19,21|27,31|35,35|38,44|46,49|52,54|58,59|61,67|69,86|88,91|109,114|117,123|125,129|131,137|140,144|148,149|157,158|160,160|169,174|176,181|183,185|187,187|192,203|205,212 E---------?????????TTS???-?SEEEE???B??TTTSSSS?EEES--STT??-EE?TTEEESS?HHHHHHHHHHHHHHTTSS?SEEE???--------??????EEEEEE--EEEEEEE?TTSSS?EEEEEEE--EEEEE---TT-------TT-E--------EEEEEE-EEEEEE?SSS-S----HHHHHHHHHHHH-HHHHHHHH 2IQI|A PF03887.9_YfbU_seed 4 187 !Q:2,3|21,21|23,28|45,45|54,54|57,61|85,85|88,98|104,106|108,108|110,111|114,114|129,131|136,137|144,144|147,148|157,160|168,172|175,176|186,186 Q:0,1|4,20|22,22|29,44|46,53|55,56|62,84|86,87|99,103|107,107|109,109|112,113|115,128|132,135|138,143|145,146|149,156|161,167|173,174|177,185 GG??HHHHHHHHHHHHHHHHH?G------GGHHHHHHHHHHHHHT?HHHHHHHH-TT?????HHHHHHHHHHHHHHHHHHHHHHT?SS------?????GGGGS???B?T--TT?HHHHHHHHHHHHTS-??STTS??TTTTTB?SS??HHHHHHHH----HHHTTSS---??SS??HHHHHHHHT? 1WPB|A PF03888.9_MucB_RseB_seed 8 297 !Q:11,11|32,32|35,36|47,47|51,52|65,65|69,70|75,76|79,79|84,84|89,90|124,124|126,126|137,138|146,146|150,150|164,167|177,183|185,196|202,204|207,207|217,217|222,223|232,232|235,235|242,242|245,246|249,251|256,256|259,259|267,270|282,282|296,297 Q:0,10|12,31|33,34|37,46|48,50|53,64|66,68|71,74|77,78|80,83|85,88|91,123|125,125|127,136|139,145|147,149|151,163|168,176|184,184|197,201|205,206|208,216|218,221|224,231|233,234|236,241|243,244|247,248|252,255|257,258|260,266|271,281|283,295 HHHHHHHHHHS?EEEEEEEEETTEEEEEEEEE-EE?-SSSEEEEEEE?SSS??EEEEETTEEEEE?TTS??EEEE-?SS?SSSS?GGGG??HHHHTTTEEEEEEEEEEETTEEEEEEEEEETTS?S?EEEEEEETTT??EEEEEEE?TTS?EEEEEEEEEEEES????HHHHHHHHS????---B???????-????SEEES???TT?EEEEEEEEE?SSSS??EEEEEEEE?SS?EEEEEE-EE??TT???EEEE?SS?EEEEEEE----TTEEEEEEESS?HHHHHHHHTTEEE?- 2V42|A PF03892.9_NapB_seed 75 168 !Q:0,39|43,43|46,46|50,59|61,82|84,84|86,87|90,94|108,120|126,128|131,132|134,135|138,139|144,144|149,150|152,152|156,158|161,161|163,166 Q:40,42|44,45|47,49|60,60|83,83|85,85|88,89|95,107|121,125|129,130|133,133|136,137|140,143|145,148|151,151|153,155|159,160|162,162|167,167 ------------------------------------????TTT?SS?TTS?-????????B-----?????????????????B?S??TT---??EETTEEHHHHHHS?????????????GGGGB?--TT??B?-SS??GGGS?GGGT??B?BSS-??SS?B????G 3O5A|B PF03893.11_Lipase3_N_seed 10 92 !Q:0,28|35,37|53,53|62,64|72,76|82,82|88,88 Q:29,34|38,52|54,61|65,71|77,81|83,87|89,91 ---------------------------??EEEEEE???HHHHHHHHHHHHHHH-HGGGSSTT???BTTTBSS-----TTGGG?TTEEE-EEE 4JEI|A PF03894.10_XFP_seed 6 187 !Q:17,18|27,27|33,33|40,41|44,45|47,50|54,57|63,63|68,68|70,70|86,86|118,118|122,124|126,126|134,134|137,138|142,142|146,148|158,159|162,164|170,171|186,186 Q:0,16|19,26|28,32|34,39|42,43|46,46|51,53|58,62|64,67|69,69|71,85|87,117|119,121|125,125|127,133|135,136|139,141|143,145|149,157|160,161|165,169|172,185 HHHHHHHHHHHHHHSTT--TEEEEESS?TTTTT?GGGGGT??EE??S????TTT?--?SEESS?SEEE?S?HHHHHHHHHHHHHTT?EEEEEEEGGGGGGGHHHHHHHHHHHHHHHHH?TTS???B?EEEEEES?TT??TTS?GGG???THHHHHGGG??TT???EEEEE??SHHHHHHHHHHHHH? 3AHD|A PF03895.10_YadA_anchor_seed 110 97 !Q:6,8|20,26|28,29|32,32|56,56|60,62|72,80|84,86|96,97 Q:0,5|9,19|27,27|30,31|33,55|57,59|63,71|81,83|87,95 HHHHHH---HHHHHHHHHHT?--????S--TT?EEEEEEEEEETTEEEEEEEEEEE?TTS?--EEEEEEEEE---------ETT???EEEEEEEEE?- 2LME|A PF03898.8_TNV_CP_seed 4 208 !Q:0,17|30,31|43,44|47,47|56,57|64,64|83,84|87,87|90,91|93,93|103,103|107,109|121,122|124,124|139,139|145,145|149,150|160,162|177,177|189,189|192,194|206,207 Q:18,29|32,42|45,46|48,55|58,63|65,82|85,86|88,89|92,92|94,102|104,106|110,120|123,123|125,138|140,144|146,148|151,159|163,176|178,188|190,191|195,205 ?????????-----????HHHHHHHHHHTS??EEEEEEEEEEE??SS?EEEESSTT??BSSSTT?BSTTEEEEEEEEEEEEEE??SS?EE--E-EEEEEEETT?SSS???HHHHBSSSSTT??B?HHHHHTTSEEEEEE-EEEEE?TTS??EEEEEEEEE??-EEEBSSSSSSGGGB?TTEEEEEEEES?SS?--EEEEEEEEEEE?? 1VTZ|0 PF03900.10_Porphobil_deamC_seed 21 104 !Q:15,16|20,20|29,32|36,51|60,60|64,70|72,72|81,86 Q:0,14|17,19|21,28|33,35|52,59|61,63|71,71|73,80|87,103 HHHHHHHHHHHHHHT??TTS?EEEEEEEE----TTE----------------EEEEEEEE?TTS-------S?EEEEEEEE-----?GGGHHHHHHHHHHHHHH 1PDA|A PF03902.8_Gal4_dimer_seed 4 57 !Q:0,4|18,18|26,28|47,48|50,51|54,56 Q:5,17|19,25|29,46|49,49|52,53 ?????HHHHHHHHHHHHH?SSSSSSS???HHHHHHSSHHHHHHHHHH??S??SS??? 1D66|A PF03909.12_BSD_seed 81 82 !Q:0,0|4,9|11,13|17,24|35,35|38,38|48,54|59,59 Q:1,3|10,10|14,16|25,34|36,37|39,47|55,58|60,81 ?SSS????-?H---HHH--------HHHHHHHHHH?HH-HHHHHHHTT-------TTTS?HHHHHHHHHHHHHHHHHHHHHT 2DII|A PF03911.11_Sec61_beta_seed 33 43 !Q:0,12|14,19|22,22|40,40 Q:13,13|20,21|23,39|41,42 ???????????-?S?-????SS?SHHHHHHHHHHHHHHHS?SS 2YXQ|C PF03912.9_Psb28_seed 34 118 !Q:7,9|11,13|20,20|22,22|26,26|36,36|39,40|44,45|47,54|67,68|77,81|93,93|113,117 Q:0,6|10,10|14,19|21,21|23,25|27,35|37,38|41,43|46,46|55,66|69,76|82,92|94,112 EESBTTB???S??-EEEEEE?T-TSS?EEEEEEEES?HH--HHH??S----????EEEEETTEEEEE??EEEEEETT-----EEEEEEEEEEE?SHHHHHHHHHHHHHHHHHS????? 2KVO|A PF03913.8_Amb_V_allergen_seed 3 44 !Q:0,3|5,5|12,12|19,19|25,29|43,43 Q:4,4|6,11|13,18|20,24|30,42 ????E-ESSTTS?TTSEEE?SSSSS?----EEESSHHHHHHHH? 2BBG|A PF03915.8_AIP3_seed 18 506 !Q:0,265|305,309|388,505 Q:266,304|310,387 ---------------?----?------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------??-----????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?????TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??????????------------------------------------------------------------------------------------------------------------ 3ONX|A PF03917.12_GSH_synth_ATP_seed 10 528 !Q:0,1|6,6|26,26|30,30|47,48|53,53|57,57|81,81|96,101|115,120|124,130|144,146|152,155|163,163|166,168|189,191|195,196|201,204|221,235|237,237|240,240|247,247|250,250|268,270|275,275|286,286|289,298|300,300|316,316|322,322|344,344|369,371|373,373|383,385|391,391|393,397|406,406|414,414|416,417|421,422|424,424|435,442|446,446|451,456|458,458|465,465|488,489|510,510|512,514|520,520|524,524 Q:2,5|7,25|27,29|31,46|49,52|54,56|58,80|82,95|102,114|121,123|131,143|147,151|156,162|164,165|169,188|192,194|197,200|205,220|236,236|238,239|241,246|248,249|251,267|271,274|276,285|287,288|299,299|301,315|317,321|323,343|345,368|372,372|374,382|386,390|392,392|398,405|407,413|415,415|418,420|423,423|425,434|443,445|447,450|457,457|459,464|466,487|490,509|511,511|515,519|521,523|525,527 ??TTSS?HHHHHHHHHHHHHHHHHTT?EEE?TTSTTTTTSTTSSEEE??EESS?EEE?HHHHHHHHHHHHHHHHHHHHHHT?HHHHHHHTHHHHHH-----?HHHHHHHHHHHHH------HHH--?????EEEEEEEEEEEEE---TTTTE----EEEEEEE?SS???HHHHHHHHHHHHHHHHHHHH---HHT??GGGS????HHHHHHHHHHHHHHHH---------------T?TT?EEEEEE?SS?TTHHHHHHHHHHHHHHH???EEEE?HHHHHHHEEE?TT----------S?EEETTEEEEEEEEES?SSGGG?SSHHHHHHHHHHHHSSSEEET?HHHHHHTSHHHHHHTTSTTTHHHH???H-HHHHHHHHH???EEETT?T-----THHHHHHH?GGGEEEE?S??SSS??B?HHHHHHHHHH????????GGG?EEEE??????E-EEEEEE-TTEEEEEEEEEEEEEEEEEEEE--TTEEEEEEEEEEEEEEEETT?S???TTTTT?EEE?EEE 3KAL|A PF03918.9_CcmH_seed 177 209 !Q:0,42|45,49|53,57|72,72|74,75|79,79|84,86|104,105|121,121|123,123|125,142|144,208 Q:43,44|50,52|58,71|73,73|76,78|80,83|87,103|106,120|122,122|124,124|143,143 ?---?-------------------------------------?SS???--SSH-----HHHHHHHHHHHSSB?S?-TTS?TTTS???HHHHHHHHHHHHHHHHT??HHHHHHHHHHHHTTT?B?S??----------------S?------------------------?-------------------------------------?? 2KW0|A PF03919.10_mRNA_cap_C_seed 11 139 !Q:2,3|12,12|16,17|19,19|23,23|29,29|34,34|37,38|47,47|51,56|64,66|79,80|83,83|90,92|99,101|108,108|111,111|114,115|131,132 Q:0,1|4,11|13,15|18,18|20,22|24,28|30,33|35,36|39,46|48,50|57,63|67,78|81,82|84,89|93,98|102,107|109,110|112,113|116,130|133,138 GG??EEEEEEEE?EEE--E?TTS?TTSTT?EEEE?SS??SEEEEEEE?STT-----?EEEEEEE???HHHHHHHHHSSS??TT?EEEEEE--?SSSTTE---EEEEEE?TT?SS??BHHHHHHHHHHHHHS??HHHHHH 3RTX|A PF03921.9_ICAM_N_seed 5 93 !Q:0,4|15,15|28,28|31,31|38,38|48,49|62,62|64,64|87,87|89,92 Q:5,14|16,27|29,30|32,37|39,47|50,61|63,63|65,86|88,88 -????EEEESSEEEE?TTEEEEEEEEES?SS?SEEEEE?SSEEEEEEE--ETTEEEEEEEEE?S?EEEEEEEEETTEEEEEEEEEEE?B???? 1Z7Z|I PF03922.9_OmpW_seed 9 227 !Q:0,0|3,3|16,17|20,23|29,29|31,31|34,34|38,40|42,43|64,76|81,81|90,96|102,104|109,110|117,117|123,124|145,145|153,153|159,160|176,176|189,190|198,199|204,204|213,214 Q:1,2|4,15|18,19|24,28|30,30|32,33|35,37|41,41|44,63|77,80|82,89|97,101|105,108|111,116|118,122|125,144|146,152|154,158|161,175|177,188|191,197|200,203|205,212|215,226 ?TT?EEEEEEEEEEEE??EE???-EETTE-E?TT?EEE---E??EEEEEEEEEEESSSSEEEEE-------------EEES?EEEEEEEE???????EEEEE---EEEE??EEEEEE?TTTTS??SEEEEEEEEEEEEEEEEEEE?HHHHHTT?EEEEE??EEEEEEEEEEEEESS-SSEEEEEEEEEE??EEEEEEE??TTTT?SEEEEEEE??EEEEEEEEEEEE 2F1V|A PF03924.8_CHASE_seed 191 295 !Q:2,6|17,19|24,24|32,33|37,37|43,44|46,47|56,69|71,77|79,79|81,82|85,99|101,104|108,108|114,114|118,120|141,144|151,153|156,158|161,163|167,174|179,182|189,189|192,206|209,210|214,216|219,222|234,234|249,250|252,255|265,281|287,287|291,291|293,295 Q:0,1|7,16|20,23|25,31|34,36|38,42|45,45|48,55|70,70|78,78|80,80|83,84|100,100|105,107|109,113|115,117|121,140|145,150|154,155|159,160|164,166|175,178|183,188|190,191|207,208|211,213|217,218|223,233|235,248|251,251|256,264|282,286|288,290|292,292 SS???-?HHHHHHHHHH---TGGG?TTEEEEE--EEE?EEHHH--H--HHHHHHHT--------------S??-----B?T--TT-------------??B????SEE?BEEEE?GGG---GGGBTBBGGGSHHHHHHHHH----HHHHSS?--EE???EE--?TTT?------?EEEE----EEEEEE?TT??-------------SS??HHH---HH----HTEEEEEEEEE?HHHHHHHHHHTSTT--G----GGEEEEEEE----------------?SSTTS?EEE-E??- 3T4S|A PF03925.8_SeqA_seed 37 298 !Q:0,0|6,6|17,17|22,23|36,61|66,151|160,176|190,191|208,208|217,218|221,223|226,228|243,252|256,256|261,261|265,266|268,268|285,286|297,297 Q:1,5|7,16|18,21|24,35|62,65|152,159|177,189|192,207|209,216|219,220|224,225|229,242|253,255|257,260|262,264|267,267|269,284|287,296 ?EEEEE?HHHHHHHHTT?SSTT??HHHHHHHHHHHG--------------------------GGSS??-----------------------------------------------------------------------------------?SSHHHHHH-----------------HHHHHHHSHHHHH??SHHHHHHHHHHHHHHH?HHHHHHHH--HT???SS???EESSHHHHHHHSSS--------??EEE?TTSS?EEE??S?HHHHHHHHHHHHHHTT??HHHHHHHHHH? 3FMT|A PF03927.8_NapD_seed 59 84 !Q:0,1|3,3|13,13|30,30|35,37|48,48|72,74|77,80|83,83 Q:2,2|4,12|14,29|31,34|38,47|49,71|75,76|81,82 ??S-SEEEEEEEE?HHHHHHHHHHHHHSSS?EEEE???SSSEEEEEEE?SSHHHHHHHHHHHHHSTTEEEEE???EE---?SS? 2PQ4|A PF03928.9_DUF336_seed 36 154 !Q:0,3|9,12|27,30|35,35|39,39|42,42|46,46|50,50|53,54|74,79|90,91|98,106|109,111|114,114|120,120|124,124|127,127|135,135|153,153 Q:4,8|13,26|31,34|36,38|40,41|43,45|47,49|51,52|55,73|80,89|92,97|107,108|112,113|115,119|121,123|125,126|128,134|136,152 ????HHHHH----HHHHHHHHHHHHTT??-?EEEE-EET-TS?EEE-EEE?TT??TTHHHHHHHHHHHHHHHTS-----?HHHHHHGGGT-?GGGGGS---------TT???SS?EEEEE-ETT-EE-EEEEEEE?SSSHHHHHHHHHHHHTT? 3FPW|A PF03930.9_Flp_N_seed 7 90 !Q:3,7|11,13|29,29|42,42|44,44|46,46|61,61|67,76 Q:0,2|8,10|14,28|30,41|43,43|45,45|47,60|62,66|77,89 HHH-----TTT???BHHHHHHHHHHHHTT?EEETTTTEEEEE?S?S?HHHHHHHHHHHSTT?EEEEE??????????HHHHHHHHHHHHH 1M6X|A PF03931.10_Skp1_POZ_seed 17 67 !Q:0,1|6,6|10,10|15,15|30,42|46,46|50,50|66,66 Q:2,5|7,9|11,14|16,29|43,45|47,49|51,65 ??EEEE?SSS?EEEE?TTTSSSSHHHHHHH??????????-??EEE?TTS?HHHHHHHHHHHHHTS? 3L2O|A PF03932.9_CutC_seed 8 211 !Q:0,0|20,20|26,26|28,28|33,33|35,37|47,49|51,52|54,54|59,60|65,65|67,69|88,88|94,95|97,97|103,103|116,117|124,124|130,130|132,134|147,148|153,153|157,158|174,174|177,178|180,180|187,188|198,198|201,201|207,208 Q:1,19|21,25|27,27|29,32|34,34|38,46|50,50|53,53|55,58|61,64|66,66|70,87|89,93|96,96|98,102|104,115|118,123|125,129|131,131|135,146|149,152|154,156|159,173|175,176|179,179|181,186|189,197|199,200|202,206|209,210 ?EEEEEESSHHHHHHHHHTT?SEEEE?B?GGGT?B???HHHHHHHHH---H??S?EEEB??SSSS?S???HHHHHHHHHHHHHHHHTT?SEEEE??B?TTSSB?HHHHHHHHHHHT--TSEEEE?GGGGG?S?--HHHHHHHHHHHT??EEEE?TTS--SSTTTTHHHHHHHHT?SS??E-EEEESS??HHHHHHHHH-HT?SEEEE??EE 1X7I|A PF03934.8_T2SK_seed 106 490 !Q:0,6|37,41|44,46|48,52|54,55|60,60|63,65|67,69|76,96|98,98|118,148|151,185|189,189|204,211|230,257|260,261|265,267|272,273|279,279|281,285|287,288|300,301|314,315|317,322|324,325|327,328|334,336|348,361|367,380|383,385|387,389|397,399|402,408|412,412|414,414|421,424|431,433|435,436|445,448|466,480|488,488 Q:7,36|42,43|47,47|53,53|56,59|61,62|66,66|70,75|97,97|99,117|149,150|186,188|190,203|212,229|258,259|262,264|268,271|274,278|280,280|286,286|289,299|302,313|316,316|323,323|326,326|329,333|337,347|362,366|381,382|386,386|390,396|400,401|409,411|413,413|415,420|425,430|434,434|437,444|449,465|481,487|489,489 ???????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----TT--?S-----S??TTSG-GG---S?-?EEEEET---------------------T-EEEEEEEEETTSSEEGGGG-------------------------------GS???--------------------------------SSS?HHHHHHHHHHHTTT??------HHHHHHHHHHHHHHHSSS----------------------------SS??SSS???HHHH--HTSSS?B??-??S??SSGGGGGGSTT??HHHHHHHTTTEE??S-?----S--S??EETTT?-?GGGTHHHHHHT???----???????HHHHT----------?--?TT-??S--?HHHHHTS---GG-------GSS-S?HHHHHH----HHHHEE---S??SEEEEEEE----EEETTEEEEEEEEEEEE---------------ETTEEEE-E 2OCE|A PF03935.10_SKN1_seed 26 593 !Q:5,17|19,22|25,28|32,32|36,36|41,42|45,72|75,92|99,99|103,103|111,112|114,130|132,132|134,174|178,178|181,181|183,183|186,200|202,217|227,232|245,279|281,302|305,316|320,320|325,337|344,346|349,349|354,360|365,376|382,401|404,409|411,411|415,415|419,426|429,429|432,432|441,442|444,448|450,456|479,489|492,492|502,503|507,510|513,516|530,593 Q:0,4|18,18|23,24|29,31|33,35|37,40|43,44|73,74|93,98|100,102|104,110|113,113|131,131|133,133|175,177|179,180|182,182|184,185|201,201|218,226|233,244|280,280|303,304|317,319|321,324|338,343|347,348|350,353|361,364|377,381|402,403|410,410|412,414|416,418|427,428|430,431|433,440|443,443|449,449|457,478|490,491|493,501|504,506|511,512|517,529 EEEEE?----------??S---?TT????TTT?EEE?BSSS??TT---------------------??----?EE???---------------TTTEEE?SSS?EEEEEEE-?T-----------------T-S?----------------------------------------EEE?EE-E?TT---------------T???-----------?-SEEEEEEEE??---?STTEEEEEEEEE-----------------------------------T----------------------TT------------TTS?TTTT-----?-------EEEEEE-??TT?TTEE-------EEEE------------EBTTB-------------------?GG------G?EEE?STT??------GG-GS?EEEEEEEE--T-----T-------EEEEEETTEEEEEEEGGGSTTS?-------???SS?EEEEEEEEE??TTT????TT??--SSEEEEEEEEEEE-??????--------------------------------------------????????-?--- 4DFS|A PF03936.11_Terpene_synth_C_seed 87 358 !Q:5,7|11,14|42,49|61,63|66,67|88,92|96,97|100,101|105,107|110,113|123,130|133,134|139,139|142,142|167,167|170,177|200,205|209,214|228,228|240,243|246,248|259,259|261,263|276,279|284,322|327,336|352,353 Q:0,4|8,10|15,41|50,60|64,65|68,87|93,95|98,99|102,104|108,109|114,122|131,132|135,138|140,141|143,166|168,169|178,199|206,208|215,227|229,239|244,245|249,258|260,260|264,275|280,283|323,326|337,351|354,357 HHHHH---HHH----HHHHHHHHHHHHHHHHHHHHHHTHHHH???-????HHHHHHHHHHH???GG--GHHHHHHHHHHHHHHHHHHH-----HHH--TT??HHH---HH----HHHHHHHHT--------SS--GGGG-GS?HHHHHHHHHHHHHHHHHHHHHHHH-HS?-----??HHHHHHHHHHHHHHHHHHHHHH------HHT-????-HHHHHHHHHHHTS?HHHHHHHHHHS---?SS??-HHHHHHHTTT?H---HHHHHHHHHHHH----HHHH??--------------------------???????????HHHH?????-????HHHHHHHHHHHHHHH--HHHH 3LZ9|A PF03937.11_Sdh5_seed 149 96 !Q:0,0|9,11|29,30|34,34|43,43|49,51|63,70|73,73|75,78|84,88|96,96 Q:1,8|12,28|31,33|35,42|44,48|52,62|71,72|74,74|79,83|89,95 ?HHHHHHHT-??SSHHHHHHHHHHHHHHG--GGS?HHHHHHHH-HHHTS?--HHHHHHHHTTS--------SB?S----SHHHH-----HHHHHHH- 1X6I|A PF03938.9_OmpH_seed 151 414 !Q:0,65|70,70|79,79|85,88|97,100|103,105|111,188|197,199|209,212|215,226|233,234|237,238|242,262|277,279|282,308|316,323|332,332|334,336|347,350|353,353|359,370|374,388|393,395|397,398|401,401|404,404|412,413 Q:66,69|71,78|80,84|89,96|101,102|106,110|189,196|200,208|213,214|227,232|235,236|239,241|263,276|280,281|309,315|324,331|333,333|337,346|351,352|354,358|371,373|389,392|396,396|399,400|402,403|405,411 ?????------???--------------------????---??----------------------?EEEE?SSTTHHHH-HHHTS----HHHHHHHH----HH---HHHHH------------------------------------------------------------------------------HHHHHHHH---HHHHHHHTT?--?SS------------HHHHHH--HH--HHT---------------------THHHHHHHSTTTHH---HH---------------------------HHHHHHH--------HHHHHHHH-H---HHHHHHHHHH----HT?SEEEE------------GGG---------------EEEE--?T--TS-EE?HHHHHHH?? 4KQT|A PF03939.8_Ribosomal_L23eN_seed 47 99 !Q:0,54|57,88|91,91|93,93|96,98 Q:55,56|89,90|92,92|94,95 ???--???????-------------???????--???---------???-?????SS???------------------???????????SS?S?SS??? 3J39|X PF03941.10_INCENP_ARK-bind_seed 20 64 !Q:0,21|30,30|41,44|50,56|61,63 Q:22,29|31,40|45,49|57,60 ----------???---??????GGGSHHHH-HHHHHHHHHS?-??HHHHH???????STTT??? 2VGO|C PF03943.8_TAP_C_seed 8 51 !Q:11,13|27,27|43,43|45,45|50,50 Q:0,10|14,26|28,42|44,44|46,49 HHHHHHHHHHH???HHHHHHHHHHTTT?HHHHHHHHHHHHHTT?S?GGGG? 2JP7|A PF03944.9_Endotoxin_C_seed 80 193 !Q:8,8|12,14|16,18|20,20|24,26|28,28|33,33|36,36|44,48|56,58|60,61|63,63|66,67|69,69|78,78|81,81|95,101|106,108|110,110|112,116|118,127|130,130|132,132|137,137|140,146|148,150|155,155|161,166|172,172|175,178|188,189 Q:0,7|9,11|15,15|19,19|21,23|27,27|29,32|34,35|37,43|49,55|59,59|62,62|64,65|68,68|70,77|79,80|82,94|102,105|109,109|111,111|117,117|128,129|131,131|133,136|138,139|147,147|151,154|156,160|167,171|173,174|179,187|190,192 EEEEEGGG?SEE-?-T---T?EEE???S-SSSS?EE-EESSSEE-----EEEEEEE---E?-S?TT??E-EEEEEEEE-SS?EEEEEEETTEEEE-------EEEE???S?T-----T??----??--GG-G?EEEE?SS------?B??-SSSE-EEEEE------EEESS?TT--??EEEEEEEEE--ETT 1I5P|A PF03945.9_Endotoxin_N_seed 38 270 !Q:13,15|17,18|27,30|37,39|43,45|60,64|84,88|103,103|107,112|136,136|138,139|141,145|147,149|176,176|180,181|187,193|222,232|235,237|266,266 Q:0,12|16,16|19,26|31,36|40,42|46,59|65,83|89,102|104,106|113,135|137,137|140,140|146,146|150,175|177,179|182,186|194,221|233,234|238,265|267,269 HHHHHHHHHHHHH??-S--SSHHHHHH----HHHHTT???SSH---HHHHHHHHHHHHHT-????HHHHHHHHHHHHHHHHHHH-----HHHHHHHHHHHSTT?HHH------HHHHHHHHHHHHHHHHHHGGGGS?T--T?----T---TTTHHHHHHHHHHHHHHHHHHHHHHH-HHT??HHHHH-------HHHHHHHHHHHHHHHHHHHHHHHHHHHT?---------?SS---HHHHHHHHHHHHHHHHHTHHHHTTGGGG?TTT 1I5P|A PF03946.9_Ribosomal_L11_N_seed 167 68 !Q:0,2|6,6|9,12|25,26|41,45|48,49|52,52|60,60|62,63|66,66 Q:3,5|7,8|13,24|27,40|46,47|50,51|53,59|61,61|64,65|67,67 ???EEE?SS????HHHHTTHHHHHS??HHHHHHHHHTTTTS-----ST--TS?EEEEEEE?S--SS?E 2ZJQ|F PF03947.13_Ribosomal_L2_C_seed 58 144 !Q:4,4|12,12|16,16|19,19|21,21|27,29|31,32|36,38|46,47|49,49|55,55|59,59|61,61|68,72|78,78|83,89|91,92|101,111|116,116|120,121|124,124|128,131|136,138|143,143 Q:0,3|5,11|13,15|17,18|20,20|22,26|30,30|33,35|39,45|48,48|50,54|56,58|60,60|62,67|73,77|79,82|90,90|93,100|112,115|117,119|122,123|125,127|132,135|139,142 SSTT?EEETTTS?SSS?EE?B?SSTTS???B??STT???EEEEEET--T-EEEEE?TTS?E-EEEETT?----EEEES?BSSS???????S-?STTTTTTT?-----?????SSSS?TTT??SS?SSS????SSSS???TTSS? 2ZJQ|A PF03948.9_Ribosomal_L9_C_seed 147 105 !Q:2,5|8,9|18,19|22,25|28,31|33,38|41,43|56,61|64,64|66,68|71,78|81,82|86,87|91,92|96,97|99,100|102,104 Q:0,1|6,7|10,17|20,21|26,27|32,32|39,40|44,55|62,63|65,65|69,70|79,80|83,85|88,90|93,95|98,98|101,101 HH----ST--THHHHHHT--TS?--?EE????S?-????SS???HHHHHHHHHTTT-?????SS?S??-SS--?-????SB??EEE??SSS??EEE??E--E??? 2XG2|I PF03949.10_Malic_M_seed 66 324 !Q:21,24|26,31|34,35|40,41|43,44|62,62|64,65|67,69|85,85|89,90|93,107|113,116|118,118|121,140|149,150|156,156|158,160|163,163|165,165|176,176|178,183|185,185|190,191|197,197|200,200|211,212|219,222|225,225|229,229|232,233|236,237|244,245|256,256|259,260|275,276|279,292|297,297|299,299|302,303 Q:0,20|25,25|32,33|36,39|42,42|45,61|63,63|66,66|70,84|86,88|91,92|108,112|117,117|119,120|141,148|151,155|157,157|161,162|164,164|166,175|177,177|184,184|186,189|192,196|198,199|201,210|213,218|223,224|226,228|230,231|234,235|238,243|246,255|257,258|261,274|277,278|293,296|298,298|300,301|304,323 THHHHHHHHHHHHHHHHHHTS?---G------GG??EEEE??S--HHHHHHHHHHHHHHHHH-T??H---HHHHTTEEEEETTEE?BTT?-SS--?------?-----TTGGG----G?BS?????--------------?HHHHHHHH??SEEEE?S?-?TT?S?HHHHHHHHHH?S------S?EEEE??SSGGG?SS?HHHHHHHTTT??EEEESS????EE?TTS?EE??EE??GGGTHH--HHHHHHHHHT?SS??HHHHHHHHHHHHHT??HH--------------HHHH-T?SS??GGGHHHHHHHHHHHHHHHHH 1LLQ|A PF03950.13_tRNA-synt_1c_C_seed 111 267 !Q:0,1|4,4|8,10|17,17|21,29|31,38|40,41|51,52|56,56|62,65|67,69|82,86|89,91|96,96|98,98|106,106|108,108|113,113|118,119|121,121|124,126|128,129|135,137|140,157|160,160|162,163|165,168|171,172|176,176|182,183|185,187|190,196|199,199|204,210|216,219|222,222|227,227|230,231|237,237|241,243|246,247|250,254|266,266 Q:2,3|5,7|11,16|18,20|30,30|39,39|42,50|53,55|57,61|66,66|70,81|87,88|92,95|97,97|99,105|107,107|109,112|114,117|120,120|122,123|127,127|130,134|138,139|158,159|161,161|164,164|169,170|173,175|177,181|184,184|188,189|197,198|200,203|211,215|220,221|223,226|228,229|232,236|238,240|244,245|248,249|255,265 ??EE?EES---SEEEEE-ESS---?---?-S--------S??EEEEESSTT?-GGG?EEEEE??--S---EEEEEGGGEESS---??TT?-?SEET-T-SEEEETT-S?EEEE-EEEE??T-TT???E--EEEEE?--SS???????--???-????-EE?B??G----GG?-EEE-EEEEE??S---BS-------SS?GGGS-------TTGGG----GB?TTSE-EE--EEEEE?GGG---GG??BS??---EEETTSEEEEE? 2HZ7|A PF03951.14_Gln-synt_N_seed 188 130 !Q:10,10|14,14|17,23|29,35|37,38|42,50|54,62|65,65|67,69|81,82|84,85|92,94|98,100|103,103|105,111|114,115|119,119|128,128 Q:0,9|11,13|15,16|24,28|36,36|39,41|51,53|63,64|66,66|70,80|83,83|86,91|95,97|101,102|104,104|112,113|116,118|120,127|129,129 TEEEEEEEEE?TTS?EE-------EEEEE-------G--GGH---------HHH---------HT-T??-EEEGGGGGTTS??S??EEEEEE?--GGG--?EE?S--???--SS--SEE-EEEEEEEE?S 2GLS|A PF03952.11_Enolase_N_seed 190 165 !Q:11,11|15,15|27,28|31,36|40,44|46,47|51,59|61,63|70,71|75,80|93,93|95,96|98,99|101,104|107,107|117,117|121,121|124,128|130,132|136,136|157,157|159,159 Q:0,10|12,14|16,26|29,30|37,39|45,45|48,50|60,60|64,69|72,74|81,92|94,94|97,97|100,100|105,106|108,116|118,120|122,123|129,129|133,135|137,156|158,158|160,164 BEEEEEEEEEE?TTS?EEEEEEEEETT??EE------EEE?????S??TTS????????-T---TSGGGT??HHH------HHHHHHTHHHHH-T--T-?B----TT?HHHHHHHHH-HHH?ST-----T?--TTT?HHHHHHHHHHHHHHHHHHHT-S?HHHHH 3OTR|A PF03953.12_Tubulin_C_seed 66 150 !Q:2,3|12,14|17,25|27,29|39,39|46,48|50,51|55,62|64,64|71,71|77,78|95,96|100,100|106,106|114,116|119,119|123,130 Q:0,1|4,11|15,16|26,26|30,38|40,45|49,49|52,54|63,63|65,70|72,76|79,94|97,99|101,105|107,113|117,118|120,122|131,149 TT??EEEEEEES???SS-----????S???HHHHHHGGG?GGGBSS---S??GGG--------S?EEEEEE-EEEES??HHHHHHHHHHHHHHTG--GGB?TTSTT?EEEEEES???TT?SEE--------EEEEEEEGGGHHHHHHHHH 2BTO|A PF03955.9_Adeno_PIX_seed 12 118 !Q:0,3|8,14|18,18|21,26|29,29|32,35|38,38|47,56|61,62|76,79|87,87|91,92 Q:4,7|15,17|19,20|27,28|30,31|36,37|39,46|57,60|63,75|80,86|88,90|93,117 ????TTSS???????SSS?SS??????TT?SS?-??TT?GGGSSEEE?-????????TTTT--THHHHTTTTTTTS????SSTTTTH-HHH--HHHHHHHHHHHHHHHHHHHHHHHHH 3IYN|Q PF03958.12_Secretin_N_seed 231 163 !Q:5,5|9,9|13,27|34,34|36,36|38,115|117,117|120,120|123,124|139,139|141,141|151,151|157,162 Q:0,4|6,8|10,12|28,33|35,35|37,37|116,116|118,119|121,122|125,138|140,140|142,150|152,156 EEEEE?SSS?HHH---------------HHHHHH?S-S------------------------------------------------------------------------------S?SS?TT?-EEEEETTTTEEEEE-E?HHHHHHHHH-HHHHH?????? 4EC5|A PF03959.8_FSH1_seed 52 408 !Q:0,11|17,18|21,22|40,54|57,57|63,64|68,71|75,75|78,80|87,102|108,109|114,116|118,136|141,143|157,192|194,199|225,259|261,268|276,284|288,288|294,312|316,316|322,330|333,335|338,344|354,354|358,358|361,366|382,382|397,400 Q:12,16|19,20|23,39|55,56|58,62|65,67|72,74|76,77|81,86|103,107|110,113|117,117|137,140|144,156|193,193|200,224|260,260|269,275|285,287|289,293|313,315|317,321|331,332|336,337|345,353|355,357|359,360|367,381|383,396|401,407 ??------????EEEEE??TT??HHHHHHHTHHHHHHHHH---------------TT?EEEEE??SEE?--?GGG?SS???HHHHHH----------------HHHTT??EESS???S-------------------SGGG???HHHHHHHHHHHHH------------------------------------H??---?SEEEEETHHHHHHHHHHHHHHHHST-----------------------------------T????----SEEEEES????-----EEE?TTSTT?------------------EEE?GGGTT---------TT???TT?----??EEEEEEETT?SSS?HH------HHHHHHHHHHHHTTT?TTTEEEEEESSSSS????HHHHHHH 4F21|A PF03960.10_ArsC_seed 36 122 !Q:2,2|5,5|20,21|31,33|44,44|48,48|54,54|64,72|78,78|88,88|93,93|95,95|99,99|101,106|108,108|113,114 Q:0,1|3,4|6,19|22,30|34,43|45,47|49,53|55,63|73,77|79,87|89,92|94,94|96,98|100,100|107,107|109,112|115,121 EE?SS?HHHHHHHHHHHHTT??EEEEETTTS???HHHHHHHHHH?SSG-GGGTB?TTSHHHHHH?-----???TTSBH-HHHHHHHHH?GGGB?S?EEE?S------S?EEES??TTGGGGG 1SD8|A PF03965.11_Penicillinase_R_seed 47 124 !Q:0,1|17,17|27,27|32,32|34,38|58,59|61,61|65,65|70,70|72,72|89,89|92,93|106,110|123,123 Q:2,16|18,26|28,31|33,33|39,57|60,60|62,64|66,69|71,71|73,88|90,91|94,105|111,122 ??HHHHHHHHHHHHHSS-EEHHHHHHH-HTTT-S??--?HHHHHHHHHHHHHTTSEEE??S-SSS?EEEE?S?HHHHHHHHHHHHHHHH?TT-?HHHHHHHHHHHS--???HHHHHHHHHHHH? 2D45|A PF03966.11_Trm112p_seed 69 135 !Q:7,12|18,18|24,24|27,27|31,31|36,36|39,40|42,44|56,56|69,72|74,74|77,81|87,89|111,115|120,120|124,127 Q:0,6|13,17|19,23|25,26|28,30|32,35|37,38|41,41|45,55|57,68|73,73|75,76|82,86|90,110|116,119|121,123|128,134 BGGGGGT????-?GGGTT?TTSSS?EE?TTT?EEEE?TT--S???HHHHHHHHHHS?HHHHHHHHHHTT???-S?SS?????SSGGG?-?HHHHHHHHHHHHHHTTEEEEE-----EEEE?TTT--??EEEEETT 2JR6|A PF03967.8_PRCH_seed 21 153 !Q:0,11|22,22|41,41|43,43|45,45|47,47|52,52|54,62|65,69|74,74|78,79|85,94|96,98|109,109|115,115|117,119|124,124|128,133|136,137|139,139 Q:12,21|23,40|42,42|44,44|46,46|48,51|53,53|63,64|70,73|75,77|80,84|95,95|99,108|110,114|116,116|120,123|125,127|134,135|138,138|140,152 ??-?????????HHHHHHHHHH-HHHHHHHHHHHHHTTSSS?S?B?T-TSSB?S???------SS?????EEEE?STT??EEEES?????----?S???EEESSSSTTS?EEESS?H---HHHT?GGG??????SS??B?TTSSBSEEEGGGS 3G7F|H PF03968.9_OstA_seed 50 159 !Q:7,7|12,13|17,19|45,77|80,80|86,89|92,92|97,98|100,100|103,104|109,109|116,117|128,128|134,139 Q:0,6|8,11|14,16|20,44|78,79|81,85|90,91|93,96|99,99|101,102|105,108|110,115|118,127|129,133|140,158 EEEESEE-EEET--TTT---EEEEEEEEEEEETTEEEEEEEEEEE????---------------------------??TT?EEEEE?---SS?EEEE??T-TS??EEEE?SEEEEE--GGGTEEEEEE-EEEEE------ETTEEEEEEEEEEETTTTE 2R19|A PF03971.9_IDH_seed 5 736 !Q:6,6|30,30|37,37|47,47|52,52|56,59|73,74|78,82|84,84|101,106|109,110|128,128|134,135|137,138|142,143|154,161|164,166|170,171|180,181|185,186|201,201|212,212|215,215|223,223|243,243|248,250|286,287|291,291|303,303|322,323|325,325|332,333|338,338|343,343|360,360|372,373|392,392|394,395|399,403|407,408|412,412|417,417|424,424|434,435|438,439|447,447|450,450|458,458|478,479|484,485|506,507|510,511|516,516|532,534|539,539|557,557|571,571|577,577|580,582|594,599|619,619|641,641|643,644|650,650|670,671|673,673|705,708|710,710|714,715|724,726|735,735 Q:0,5|7,29|31,36|38,46|48,51|53,55|60,72|75,77|83,83|85,100|107,108|111,127|129,133|136,136|139,141|144,153|162,163|167,169|172,179|182,184|187,200|202,211|213,214|216,222|224,242|244,247|251,285|288,290|292,302|304,321|324,324|326,331|334,337|339,342|344,359|361,371|374,391|393,393|396,398|404,406|409,411|413,416|418,423|425,433|436,437|440,446|448,449|451,457|459,477|480,483|486,505|508,509|512,515|517,531|535,538|540,556|558,570|572,576|578,579|583,593|600,618|620,640|642,642|645,649|651,669|672,672|674,704|709,709|711,713|716,723|727,734 EEEEEE?SSHHHHHHHHHHHHHHHHTGGGT?EEEEEE?SHHHHHHTT?GGGS?GGG????HHHHHHHHTTSTT??EEE?????B?TTTTHHHHHHHHHTTS??????SS??SHHHHHHHHHHHTTSBS?SHHHH??B??EEE??HHHHHHHHHS????????TT???EEE??SSSSHHHH??EEE??SSEEEEEEEEETTS?EEEEEEEEEE?TT?EEEEEEE?HHHHHHHHHHHHHHHHHHT?EEEE???TTTSTTTHHHHHHHHHHHHHHHHHHHTHHHHHHHT??GGG?HHHHHHHGGGS?HHHHHHHHHHHHHHHHHS??B?BSSTTT??BTTT?TTTS?HHHHHHHHHHTTTEEE?SSSSEEEEEEE??SSTTHHHHHHHHHHHTTT?S??TTT?????BEE??TTT?GGGG?GGGEEE?SSSEEEEEE-?SS??EEEEEEE?TT?EEEEEEE?HHHHHHHHHHHHHHHHHHT??EEEE??TTSHHHHHHHHHHHHHHTTS??TT??EEEE?HHHHHHHHHHHHHTT???EEEE?HHHHHHHHHHHHHHHHS?STTSEEEEEBSSS?EEEES?SS???HHHHHHHTTTS??????HHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHTT?S??SSTTS?TTHHHHHHHHHHHHHHHTT??S?HHHHHTTHHHHHHHTTTHHHHHHHHHTTSSS????S?SSS??HHHHHHHH???HHHHHTTS? 3MBC|A PF03972.9_MmgE_PrpD_seed 16 499 !Q:0,0|13,17|19,22|45,45|52,52|54,54|59,59|61,61|64,65|68,68|72,73|76,76|93,93|95,95|98,98|102,102|104,104|127,129|131,134|157,158|164,166|168,168|187,188|203,203|205,205|207,207|215,216|241,245|251,251|264,268|270,270|272,272|275,285|292,292|294,296|300,301|323,324|336,336|344,346|348,357|365,365|378,380|389,389|392,392|407,407|416,418|422,425|436,436|438,440|444,444|446,446|473,473|479,480|488,488 Q:1,12|18,18|23,44|46,51|53,53|55,58|60,60|62,63|66,67|69,71|74,75|77,92|94,94|96,97|99,101|103,103|105,126|130,130|135,156|159,163|167,167|169,186|189,202|204,204|206,206|208,214|217,240|246,250|252,263|269,269|271,271|273,274|286,291|293,293|297,299|302,322|325,335|337,343|347,347|358,364|366,377|381,388|390,391|393,406|408,415|419,421|426,435|437,437|441,443|445,445|447,472|474,478|481,487|489,498 ?HHHHHHHHHHHH?????H----HHHHHHHHHHHHHHHHHHHHTT?HHHHTT?S?SSTT?B?TT-?EE?TTS??EE?HHHHHHHHHHHHHHTS?S?BB?SSS?B?GGGGHHHHHHHHHHHHHHHHHT---T????BHHHHHHHHHHHHHHHHHHTTT??SGGGT---B?THHHHHHHHHHHHHHHTT??HHHHHHHHHHHHTS?B?B?GGGSTTS??THHHHHHHHHHHHHHHHHHHHHTT???-?TTTTT?TTTSHHHHHSTT?????S-S?SS-----------SHHHHH?B???SSS??TTTHHHHHHHHHHHHHHHHTT??GGGEEEEEEEE?HHHHHHH???S-------???SHHHHTT?HHHHHHHHHHHS???GGGGSHHH-HT?HHHHHHHHTEEEEE?HHHHHHHH--?TTT????EEEEEEETTS?B???EEE?S?TTSGGGHHHHHHHHHHHHHHHHHHHS?HHHHH--HHHHHHH?HHHHHHSBHH 2HP0|A PF03973.8_Triabin_seed 4 163 !Q:0,0|2,11|13,14|18,21|24,25|32,32|43,45|54,54|58,61|66,68|72,72|74,75|78,78|81,81|88,88|90,91|95,95|105,111|122,122|139,141|151,152|156,157|162,162 Q:1,1|12,12|15,17|22,23|26,31|33,42|46,53|55,57|62,65|69,71|73,73|76,77|79,80|82,87|89,89|92,94|96,104|112,121|123,138|142,150|153,155|158,161 ?T----------T??GGG????SS??HHHHSS-SEEEEESSSS???SEEEEEEE?SSS-???EEEE---EES?T--TS?TT?EEEEEE?S??TTT?EEEEEEETT?----??EEEEEEEEEE?TTSEEEEEEEEEESSS???EEEEEEESS??SSS??HHHH? 2ACP|X PF03974.8_Ecotin_seed 47 175 !Q:4,11|15,16|20,28|31,33|36,38|53,57|60,62|65,65|71,81|84,84|88,88|90,90|100,115|117,120|123,124|127,127|133,134|139,139|143,144|148,148|151,151|154,154|158,158|167,174 Q:0,3|12,14|17,19|29,30|34,35|39,52|58,59|63,64|66,70|82,83|85,87|89,89|91,99|116,116|121,122|125,126|128,132|135,138|140,142|145,147|149,150|152,153|155,157|159,166 STTT??-?????SSB??EEE?----????SS---GG---GEEEEEEEEEEEEE---?-SS???BE-EEEEE-----------EE?TTS-S?EEEEEEEEE---??------?????S??--SS??EE-EEEEB??GGGG-EEE??TTS?EE-EE?BTT?EEEEEEEE------?? 1ECY|A PF03975.8_CheD_seed 150 142 !Q:0,0|3,4|7,8|10,20|22,22|42,44|48,48|55,58|60,69|72,72|90,91|98,99|102,102|110,110|119,137|141,141 Q:1,2|5,6|9,9|21,21|23,41|45,47|49,54|59,59|70,71|73,89|92,97|100,101|103,109|111,118|138,140 ?BS??SS??S----------?G-GGBHHHHHHHHHHHHHTTT-??GGG?EEEEEE????S??-------?SS?HHHHHHHHHHHHHHHTT??EEEEEE??SS?EEEEEET-TTTEEEEE??----------???????EEE? 2F9Z|C PF03976.9_PPK2_seed 10 230 !Q:0,2|29,29|31,31|43,43|56,56|60,60|65,66|68,69|76,76|85,87|90,90|97,97|112,112|144,145|161,161|165,167|192,193|197,197|203,203|228,229 Q:3,28|30,30|32,42|44,55|57,59|61,64|67,67|70,75|77,84|88,89|91,96|98,111|113,143|146,160|162,164|168,191|194,196|198,202|204,227 ???HHHHHHHHHHHHHHHHHHHHSGGGGG?E-EEEEEEESTTS?HHHHHHHHHTTS?GGG?EEEE??S??HHHHTS?TTHHHHTT???TT?EEEEES?GGGGGTHHHHHTSS?HHHHHHHHHHHHHHHHHHHHHTEEEEEEEEE??HHHHHHHHHHHHHSS?TTS???SSTTTGGGGHHHHHHHHHHHHHHH??SSS?EEEEE?SSHHHHHHHHHHHHHHHHHHHHHH?? 3CZQ|A PF03979.9_Sigma70_r1_1_seed 31 105 !Q:0,5|9,9|12,12|17,17|19,20|23,23|25,26|33,35|38,40|42,42|44,44|55,55|65,66|73,104 Q:6,8|10,11|13,16|18,18|21,22|24,24|27,32|36,37|41,41|43,43|45,54|56,64|67,72 ??????HHH-HH-HHHH?S??TT-T??TTGGGS??-SS?--S?S-SSSHHHHTTS-SSSTTTHHH--HHHHHH-----??----?????-----??????????? 4KN4|X PF03983.7_SHD1_seed 18 70 !Q:0,10|20,21|39,39|43,43|53,53|66,68 Q:11,19|22,38|40,42|44,52|54,65|69,69 --------???SEEEEBSSS??EEEEEEEEEETTEEEEE?TTS?EEEEETTSB?HHHHHHHHHHHS???G 2HBP|A PF03985.8_Paf1_seed 12 516 !Q:0,107|109,121|123,135|137,180|195,202|204,204|207,207|210,211|218,221|227,228|230,233|235,235|238,251|256,262|264,264|269,269|291,301|303,304|307,307|310,330|332,334|338,376|379,385|393,423|429,429|431,442|447,447|451,451|467,467|472,508 Q:108,108|122,122|136,136|181,194|203,203|205,206|208,209|212,217|222,226|229,229|234,234|236,237|252,255|263,263|265,268|270,290|302,302|305,306|308,309|331,331|335,337|377,378|386,392|424,428|430,430|443,446|448,450|452,466|468,471|509,515 -----------------------------------------------------------------------------------------?-----------------?H-------------H-------------H--------------------------------------------HHHHHHHHHHHHHS-----???S?SS?TT??EEEEEE????SEEEE??S????S?SS?----------???SSSS?------S?EEEE?STTHHHHTTTSEEEEEEEEEE-----------E??TT?EE??-------------------S???GGG--?----------????????---??-----------??TT-------HHHHHHH-------------------------------HTSEE?E------------EEEE?TTS?EEEEESEEEEEETTS?EEEE-------------------------------------ETTEEEE 4M6T|A PF03986.8_Autophagy_N_seed 29 193 !Q:0,20|26,28|43,43|46,46|49,52|56,58|62,62|65,65|67,67|76,76|78,78|82,145|158,192 Q:21,25|29,42|44,45|47,48|53,55|59,61|63,64|66,66|68,75|77,77|79,81|146,157 ?????????????????????HHHHS???HHHHHHHHHHHHHH?TT?EE????TTB???TTS?TT?S?EEEEEEEE?S?TTT????-------???????????-------?????--??????????????-?????????????HHHHHHHHHHHH????----------------------????????? 2DYT|A PF03987.10_Autophagy_act_C_seed 57 113 !Q:18,27|29,29|32,33|35,36|42,44|48,75|81,81|84,98|103,104|109,109 Q:0,17|28,28|30,31|34,34|37,41|45,47|76,80|82,83|99,102|105,108|110,112 EEEEETTTTEEEEEEEEE?---------T-TS-?B??GGGGG---GTS????????--------------------EEEEE?SS---------------SSSE--EEEE?GGG 4EBR|A PF03989.8_DNA_gyraseA_C_seed 362 110 !Q:0,0|2,3|19,66|70,70|72,75|78,80|83,95|98,101|107,109 Q:1,1|4,18|67,69|71,71|76,77|81,82|96,97|102,106 ?E--EEEEETTSEEEEEEG------------------------------------------------GGS?B--??TT???EE??--------???TT--??EEEEE??? 1WP5|A PF03992.11_ABM_seed 114 116 !Q:0,0|9,9|11,11|14,14|16,16|23,23|30,35|39,39|51,59|61,67|70,70|74,74|84,86|90,90|98,106 Q:1,8|10,10|12,13|15,15|17,22|24,29|36,38|40,50|60,60|68,69|71,73|75,83|87,89|91,97|107,115 ?EEEEEEEE-E?TT?H-HHHHHH-HHHHHH------HHH-HSTTEEEEEEE---------E----?--SS?TTE-EEEEEEESS---HHH-HHHHHTS---------HHHHHHHTT 4HL9|A PF03995.8_Inhibitor_I36_seed 7 105 !Q:0,3|5,5|10,11|18,18|21,23|26,26|36,36|39,42|45,45|49,49|52,53|57,59|63,76|80,84|87,91|104,104 Q:4,4|6,9|12,17|19,20|24,25|27,35|37,38|43,44|46,48|50,51|54,56|60,62|77,79|85,86|92,103 -???S?SSSB??BBSSSS?BS???BS-SSTHHHHSS?EE????TT?BEE?SS??EEE---EEE--------??????SSS?--??SS?????BTTTTSSSSSEE? 1BHU|A PF03996.10_Hema_esterase_seed 6 415 !Q:7,7|10,11|14,15|19,19|30,34|36,36|38,39|51,51|55,55|57,59|61,61|68,68|71,71|81,81|84,85|92,93|97,103|107,107|113,115|123,125|128,128|130,135|153,153|160,163|166,167|170,170|173,175|182,183|188,188|191,193|200,203|211,211|219,219|231,231|233,233|241,241|244,245|251,251|255,255|266,270|275,275|285,285|294,294|298,299|301,303|308,315|320,324|328,331|347,348|351,356|363,364|378,378|388,388|390,391|397,399|406,407|410,411 Q:0,6|8,9|12,13|16,18|20,29|35,35|37,37|40,50|52,54|56,56|60,60|62,67|69,70|72,80|82,83|86,91|94,96|104,106|108,112|116,122|126,127|129,129|136,152|154,159|164,165|168,169|171,172|176,181|184,187|189,190|194,199|204,210|212,218|220,230|232,232|234,240|242,243|246,250|252,254|256,265|271,274|276,284|286,293|295,297|300,300|304,307|316,319|325,327|332,346|349,350|357,362|365,377|379,387|389,389|392,396|400,405|408,409|412,414 EEEEEEE?SS??EE??TTS?EEEEEEEESS?????B?S??BSSSSSEEEEE?SSS?T---T?SSHHHH?SS?HHHHHTEEE?TT??HHHHHH??SSS????--?EEE?SEEEE???GGGSGGG???SS?S?----?HHHHHHHHHHHHHHHTT?SEEEEE????EE??SS?EE???SSSTTS??SSSB?EE???BTTTTB????EEEEEEE?SEETTEE?SEEEEEEEEEE?S?HHHHHHH?SS??EEEEE?SSS?EEEEEETTTS?????STTS?EEEEEEEEE?SEEEEEEE?TTB??B???EEEE????-???EEEE?????TTS????HHHHHHHTSTTEEEE??SS????--SSBTTB??HHHHHHGGGGGSB?SEEETTEEE?S??SEESS???SSEEES??EE??TTT 1FLC|A PF03997.7_VPS28_seed 6 222 !Q:0,123|147,148|167,167|171,172|175,175|192,192|195,195|197,198|221,221 Q:124,146|149,166|168,170|173,174|176,191|193,194|196,196|199,220 ----------------------------------------------------------------------------------------------------?--------------------???HHHHHHHHHHHHHHHHHHHHHTT??BHHHHHHHHHHHHHHHHH?TTS?-TT?HHHHHHHHHHHHHHTS?TT?B??HHHHHHHHHHHHHHHHHHHHHH? 2J9V|A PF03999.7_MAP65_ASE1_seed 6 730 !Q:24,27|47,57|63,100|103,105|113,121|130,149|173,177|181,193|196,201|242,249|259,267|269,269|272,274|316,318|324,339|347,348|390,392|399,403|406,407|409,418|465,465|471,471|474,478|480,482|484,484|517,517|519,521|533,539|556,729 Q:0,23|28,46|58,62|101,102|106,112|122,129|150,172|178,180|194,195|202,241|250,258|268,268|270,271|275,315|319,323|340,346|349,389|393,398|404,405|408,408|419,464|466,470|472,473|479,479|483,483|485,516|518,518|522,532|540,555 HHHHHHHHHHHHHHHHHHHHHHHH----HHHHHHHHHHHHHHHHHHH-----------HHTTT--------------------------------??????SS???HHHHHHH---------HHHHHHHH--------------------HHHHHHHHHHHHHHHHHHHHHHH-----HHT?-----???????SS??---?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT????----SHHHHHHHH---------T?SS???TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH???HHHHH----------------HHTTTSS??SSTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS???HHHHTT--???SS??S??--------SHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHT?SSBTT-BS?----S?--H-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?S???SSSSSSHHHHH-------HHHHHHHHHHHHHHTT?????????????????----?????????---???????????---------------------------------------------------------------------------------------------------------------------------------- 3NRY|A PF04002.10_RadC_seed 107 155 !Q:1,1|6,8|17,20|22,27|31,35|43,43|46,46|57,59|62,63|67,68|77,77|82,82|91,91|95,96|98,99|107,110|122,122|131,139|142,142|146,146|151,151|153,154 Q:0,0|2,5|9,16|21,21|28,30|36,42|44,45|47,56|60,61|64,66|69,76|78,81|83,90|92,94|97,97|100,106|111,121|123,130|140,141|143,145|147,150|152,152 B?SSHH---HHHHHHTT--??S-----?TTS----?EEEEEEE?TT?BEEEEEEEEE---SS??GGG??HHHHHHHH-HHTT?SEEEEEEE?SSS??S??HHHHHHH----HHHHHHHHHHT?EEEEEEEE-?-------SS?EEE-TTTT-T?? 2QLC|A PF04004.8_Leo1_seed 86 360 !Q:5,6|9,15|17,17|19,34|36,38|42,69|71,90|101,103|107,107|113,123|127,127|130,138|152,152|160,162|165,165|169,359 Q:0,4|7,8|16,16|18,18|35,35|39,41|70,70|91,100|104,106|108,112|124,126|128,129|139,151|153,159|163,164|166,168 EEEEE??TT------?E-E??--------------S???GGG?-??-????-----???--------???T--------------------THHHHHHHHT---SEE?EEEEE--?--------TTS?EE---------EEESEEEEEETTS?EEEEETT---EE-EEE-------------------------------------------?-----------------------------------------------------------------------------------??-------------------------------------------------------------- 4M6T|A PF04005.7_Hus1_seed 34 526 !Q:0,0|7,8|26,26|34,34|43,57|68,70|72,72|74,75|79,79|82,82|84,84|89,90|96,96|111,124|127,128|130,154|161,161|163,175|178,178|187,188|190,244|247,249|254,255|259,259|262,264|273,279|283,285|288,291|306,338|346,357|361,361|364,389|394,394|396,396|405,464|480,480|482,483|485,486|506,512|515,515|523,525 Q:1,6|9,25|27,33|35,42|58,67|71,71|73,73|76,78|80,81|83,83|85,88|91,95|97,110|125,126|129,129|155,160|162,162|176,177|179,186|189,189|245,246|250,253|256,258|260,261|265,272|280,282|286,287|292,305|339,345|358,360|362,363|390,393|395,395|397,404|465,479|481,481|484,484|487,505|513,514|516,522 ?EEEEEE??HHHHHHHHHHHHHHHHH?SEEEEEE?SSEEEEEE???------??????EEEEEEEGGG---T?S--EEE-EE?S-SSTT??EEEEE-EHHHHHHHGGGGGG--------------EE--E-------------------------EEEEEE?S-------------SS?EEEEEEEE??S-------------------------------------------------------SS???EEEE--EEE?EE?-?GGGGGGGS???????SEE---EE??-?HHHHHHHHHHHHTT--------------------------------?SEEEEEE?-----------TTS?EE--------------------------EEEE?S-SEEEEEEE-????????-------------------------------------??????????????EEEEEEHHHHHHHHH-H??S??SEEEEEEETTTEEEEEEES-------SS?EEEEEEE??? 3A1J|B PF04008.9_Adenosine_kin_seed 34 160 !Q:3,5|7,7|16,17|19,19|34,34|37,37|45,46|50,50|58,58|73,74|86,87|101,102|111,111|119,119|121,121|123,123|133,136|139,140|154,154|158,159 Q:0,2|6,6|8,15|18,18|20,33|35,36|38,44|47,49|51,57|59,72|75,85|88,100|103,110|112,118|120,120|122,122|124,132|137,138|141,153|155,157 EEE???T-TEEEEEEE??S-TTHHHHHHHHHHTT?SS?EEEEEEE??STT?EEEEEES?HHHHHHHHHHHHHH??TTEEEEEEESS-?HHHHHHHHHTSTT??EEEEEESS?EEEEEEE?S-S?EEEEEEEES????EE??HHHHHHHHHHHHH-TTS?? 2GL0|A PF04010.8_DUF357_seed 41 79 !Q:15,22|25,27|50,50|53,53|78,78 Q:0,14|23,24|28,49|51,52|54,77 HHHHHHHHHHHHHHT--------TS???HHHHHHHHHHHHHHHHHHHHHH-TT?HHHHHHHHHHHHHHHHHHHHHTTS? 2PMR|A PF04011.7_LemA_seed 10 198 !Q:0,22|60,60|63,63|79,89|91,92|118,118|124,124|160,180|182,197 Q:23,59|61,62|64,78|90,90|93,117|119,123|125,159|181,181 -----------------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?TT?HHHHHHHHHHHHHHH-----------H??SHHHHHHHHHHHHHHHHHHHHHHTT?HHHHH?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?????????????--??????S???--??????????? 2ETD|A PF04013.7_Methyltrn_RNA_2_seed 7 210 !Q:0,0|10,12|15,17|41,41|46,46|56,57|61,62|72,73|75,78|99,99|106,106|117,119|132,132|147,154|162,162|165,165|167,167|179,181|186,187|190,192|207,209 Q:1,9|13,14|18,40|42,45|47,55|58,60|63,71|74,74|79,98|100,105|107,116|120,131|133,146|155,161|163,164|166,166|168,178|182,185|188,189|193,206 ?EEEEEEESS???SS???GGGTTTTTTSHHHHHHHHHHHHB?SSSB?TTEEEEEEE??SSS??EEEEEETTT??S--??SSHHHHHHHHHHHHHHHHHS?TTGGGS?EEEETTEEEE???HHHHHHHHHHTT?EEEEEEEEEEEGGG????----SEEEEEE?SS?S?HHHHHHHHHTT--?EEEE??SS???HHHHHHHHHHHHHH??? 2QMM|A PF04014.13_Antitoxin-MazE_seed 145 58 !Q:2,3|10,11|19,23|25,26|28,30|32,32|39,41|45,46|54,54|56,57 Q:0,1|4,9|12,18|24,24|27,27|31,31|33,38|42,44|47,53|55,55 EE??TTSEEE??HHHHHHT-----T??T---T?EEEEEE?--TTS-?EEEEESS?S?? 1YSF|A PF04016.7_DUF364_seed 60 170 !Q:0,0|2,2|20,29|31,32|39,39|41,43|55,61|64,64|66,69|81,81|94,94|96,96|106,106|118,121|123,123|130,130|138,139|142,142|155,155|157,157|169,169 Q:1,1|3,19|30,30|33,38|40,40|44,54|62,63|65,65|70,80|82,93|95,95|97,105|107,117|122,122|124,129|131,137|140,141|143,154|156,156|158,168 ?H-HHHTTTTTTTSEEEEES?-------?-T--THHHHH-T---TTSEEEEEESS?-----?TT?E----EGGGHHHHGGG?SEEEEETHHHHH-T?HHHHHHHTT-TSSEEEEESTT????G-GGGGTT?SEEEEEE--ES?HHHHHHHHTTSS?S?GGGGEEEEEEE? 3NPG|A PF04017.7_DUF366_seed 15 208 !Q:0,3|8,9|12,14|16,16|30,32|45,46|50,51|60,66|79,79|81,85|108,113|115,116|131,131|139,139|142,142|152,153|156,157|161,161|163,164|168,171|174,175|178,181|206,207 Q:4,7|10,11|15,15|17,29|33,44|47,49|52,59|67,78|80,80|86,107|114,114|117,130|132,138|140,141|143,151|154,155|158,160|162,162|165,167|172,173|176,177|182,205 ????EEEE??SS???B?SGGGSTTHHHHHH???SSEEEEEEEEEE??GGG??BHHHHHTT??----?EEEEEEEEEEEE?S??--?HHHHHHHHHHHHHHHHHHHHTT------T??EEEETTEEEETTEE?EEEEEEE?SS?EEEEEEEES??SS??SSS?B??HHH----HT??HH----HHHHHHHHHHHHHHHHHHHHTTSB?? 2DDZ|A PF04023.9_FeoA_seed 284 177 !Q:0,0|5,6|8,8|11,17|22,27|30,30|32,32|34,43|45,76|81,92|95,96|102,103|106,106|113,113|115,115|118,119|121,122|128,147|149,149|152,153|155,158|160,161|163,163|165,165 Q:1,4|7,7|9,10|18,21|28,29|31,31|33,33|44,44|77,80|93,94|97,101|104,105|107,112|114,114|116,117|120,120|123,127|148,148|150,151|154,154|159,159|162,162|164,164|166,176 ?BGGG--S?TT------?EEEE------EE-E?S----------S--------------------------------SHHH------------HH--HHHHT??TT?EEEEEE-E?TT--S??EEEEE--------------------T-TE--E----E--E-E?HHHHTTEEEEE 1G3Y|A PF04026.7_SpoVG_seed 34 125 !Q:0,1|10,11|14,16|42,42|46,46|51,52|56,56|59,94|96,96|100,100|104,104|123,124 Q:2,9|12,13|17,41|43,45|47,50|53,55|57,58|95,95|97,99|101,103|105,122 ??EEEEEEEE??SS---SSEEEEEEEEETTTEEEEEEEEEEE-TTE-EEEE??EEE?TT------------------------------------S?EEE?EEE?SHHHHHHHHHHHHHHHHH?? 2IA9|A PF04027.8_DUF371_seed 19 140 !Q:4,5|8,12|21,21|23,25|28,28|36,36|38,39|44,44|53,56|58,58|65,70|73,73|81,82|85,89|100,103|111,111|113,114|119,119|128,128|131,131 Q:0,3|6,7|13,20|22,22|26,27|29,35|37,37|40,43|45,52|57,57|59,64|71,72|74,80|83,84|90,99|104,110|112,112|115,118|120,127|129,130|132,139 EEEE??TT?????SSEEEEES?S???TT?TTEEEBS?S??GGGS?HHHHHHHS????E-EEEEEE?-----SS?EEEEEEE??TT?????SSEEEEESSS??-?TTEEEBS?S??GGGS?HHHHHHHH-TT?EEEEEEEE 3CBN|A PF04029.9_2-ph_phosp_seed 61 292 !Q:0,1|7,7|10,10|13,21|28,28|44,44|46,46|51,51|53,53|61,69|77,78|83,84|87,87|90,90|92,92|96,103|108,112|114,114|116,116|122,122|134,136|138,140|145,145|159,166|168,170|176,177|180,180|183,184|199,213|215,217|230,235|237,237|246,246|257,261|268,268|271,271|275,279|282,283|290,291 Q:2,6|8,9|11,12|22,27|29,43|45,45|47,50|52,52|54,60|70,76|79,82|85,86|88,89|91,91|93,95|104,107|113,113|115,115|117,121|123,133|137,137|141,144|146,158|167,167|171,175|178,179|181,182|185,198|214,214|218,229|236,236|238,245|247,256|262,267|269,270|272,274|280,281|284,289 ??EEEES?SS?EE?--------SEEEEE?TTTHHHHHHHHHHTT?S-EEEE?S?HHHHHHT??-------TTEEEEE?-BTTB??TT?SB?S?GGG??------HHHH-----T-T?EEEEE?TTHHHHHHHEE--?S--?EEEE?GGGHHHHHHHHTT?------?S---EEEEE??BT-TB??HHHHHHHHHHHHHH??-------------S???HHHHHHHHHHHT?-----S?HHHHHHHH?HHHHHHHHTT?----HHHHHH-HT?TTS?????EE--ETTEEE?? 2YYV|A PF04030.9_ALO_seed 34 394 !Q:4,4|7,8|21,22|41,41|47,56|67,94|100,100|103,106|108,109|114,114|119,121|124,137|148,148|151,155|184,198|203,205|211,212|214,252|256,270|276,276|285,285|287,287|290,295|312,312|314,314|317,317|321,325|329,357|362,363|377,377|380,380|383,386|391,391 Q:0,3|5,6|9,20|23,40|42,46|57,66|95,99|101,102|107,107|110,113|115,118|122,123|138,147|149,150|156,183|199,202|206,210|213,213|253,255|271,275|277,284|286,286|288,289|296,311|313,313|315,316|318,320|326,328|358,361|364,376|378,379|381,382|387,390|392,393 EEEE?EE??EEEEEEEEESTT??HHHHHHHHTSSSEEEEEE?SSSEE----------EEEEEEETTS???-----------------------??TTSEE?SS-???S--STTS?GGGB???TT------------??EEGGGTSSSB?TT---??EEEEEEEGGGHHHHHHHHHHTHHHHGGG---------------EEEE---EEEEE??B--------------------------------------?STT--------------?TTBTS?EEEEEEEE?S?HH------HHHHHHHHHHHHHGGG-T?EE?TTS?????HHH-----------------------------HHHH?-TTHHHHHHHHHHH?TT?TT??--HHHH-HH 4G3U|A PF04032.11_Rpr2_seed 86 233 !Q:1,1|12,85|91,92|96,98|115,119|122,123|125,127|132,132|136,137|139,140|151,211|215,215|220,225|231,232 Q:0,0|2,11|86,90|93,95|99,114|120,121|124,124|128,131|133,135|138,138|141,150|212,214|216,219|226,230 H-HHHHHHHHHH--------------------------------------------------------------------------HHHTT-?HHH---HHHHHHHHHHHHHHHT??-??TT--T---TTSB?TTT??B??BTTTEEEEEE------------------------------------------------------------?SSS?EEEE------EETTT?? 2KI7|B PF04033.7_DUF365_seed 5 103 !Q:5,7|11,11|13,14|27,27|42,42|50,50|60,66|69,71|83,84|86,86|88,89|92,94|97,97|102,102 Q:0,4|8,10|12,12|15,26|28,41|43,49|51,59|67,68|72,82|85,85|87,87|90,91|95,96|98,101 EEEEE???STT?B??EEEEEEEEEEES?THHHHHHTSTTBSS?HHHHHHH-HHHHHHTSS---????SS???EEEEEEEEEEE??S?B??SS???TT?EEEE? 2KKU|A PF04036.7_DUF372_seed 15 38 !Q:20,20|23,23 Q:0,19|21,22|24,37 HHHHHHHHHHHHHHHHHHTT?EE?TTTHHHHHHHHHHH 2I52|A PF04038.7_DUF381_seed 21 64 !Q:8,10|15,15|17,19|23,23|26,27 Q:0,7|11,14|16,16|20,22|24,25|28,63 EEEEEEEE???GGGG?S---TTS?EE??TTTEEEEEEEEETTEEEEEEEEEEGGGTEEEEEEEE 2I52|A PF04041.8_DUF377_seed 8 376 !Q:0,0|2,4|7,13|16,17|23,23|26,27|30,30|33,33|52,57|67,67|71,71|73,73|84,89|92,92|95,95|98,100|103,103|107,107|109,111|132,132|155,160|167,176|182,182|185,185|187,191|202,203|207,207|209,211|218,219|224,224|232,235|237,241|244,244|249,251|257,257|259,260|267,267|275,275|280,282|296,296|299,299|303,305|313,313|316,318|337,337|340,340|344,344|364,365 Q:1,1|5,6|14,15|18,22|24,25|28,29|31,32|34,51|58,66|68,70|72,72|74,83|90,91|93,94|96,97|101,102|104,106|108,108|112,131|133,154|161,166|177,181|183,184|186,186|192,201|204,206|208,208|212,217|220,223|225,231|236,236|242,243|245,248|252,256|258,258|261,266|268,274|276,279|283,295|297,298|300,302|306,312|314,315|319,336|338,339|341,343|345,363|366,375 ?S???TT???????TT??SSEEE?TT??SB?BS?STTEEEEEEEEEEEETTE------EEEEEEEEE-TTS?E-EEEEEEESSS------SS?EE?SS???EE?TTS?B???SSEEEEEEEEETTEEEEEEE-EESSSEEEEEEEESSSSSEEEE?----?SSSSSE----------EEEEE?SS?B-----TTBEEEEEEE??SSS?S???EEEEEE--SSSS?BEEEEEE----E?--??SS?GGGS---SEEEE?S??EEETTE-EEEEEEE-EEEE---TTEEEEEEEEEEE?SS?TTS---EEEEBSS?SB???SHHHHSSSSSSBEEEEEE-EE?TTT?EEEEEEEETTTEEEEEEEE--HHHHHHHHHH 3TAW|A PF04042.11_DNA_pol_E_B_seed 34 392 !Q:6,7|9,12|15,22|34,42|46,47|55,55|61,61|68,72|74,85|87,87|90,91|110,114|123,124|130,130|132,139|144,147|150,150|154,155|159,186|190,191|200,201|208,209|211,211|216,218|222,222|227,296|299,299|315,317|320,321|324,351|354,355|357,357|366,366|369,369|371,375|380,384|387,388 Q:0,5|8,8|13,14|23,33|43,45|48,54|56,60|62,67|73,73|86,86|88,89|92,109|115,122|125,129|131,131|140,143|148,149|151,153|156,158|187,189|192,199|202,207|210,210|212,215|219,221|223,226|297,298|300,314|318,319|322,323|352,353|356,356|358,365|367,368|370,370|376,379|385,386|389,391 EEEEES??S?---SS???----?HHHHHHHHHHH---------HTT??SEEEEES?SSBTT?HHHHHT?????T------------T?SS??SSHHHHHHHHTHHHHTTS?----TTSEEEEE??TTBTT?S------??SBSB????TT-TTT??TTT----------------------------EEE??BSEEEEET--TEEEEE??S?HHHH???EEE?HHHH----------------------------------------------------------------------HS?HHHHHHHHHHHHTBS???SS??EE????????????????????????????EE??B?GGGGGGGB?GG-G?--??SEEE???--SS??EEE 3E0J|A PF04043.10_PMEI_seed 142 300 !Q:0,1|3,9|13,15|21,22|25,32|43,48|54,55|58,60|62,65|72,72|87,87|89,92|98,120|124,125|128,133|137,140|151,151|153,153|157,157|164,192|195,197|199,199|203,209|214,214|220,223|231,232|235,252|256,265|270,271|275,279|286,292 Q:2,2|10,12|16,20|23,24|33,42|49,53|56,57|61,61|66,71|73,86|88,88|93,97|121,123|126,127|134,136|141,150|152,152|154,156|158,163|193,194|198,198|200,202|210,213|215,219|224,230|233,234|253,255|266,269|272,274|280,285|293,299 ??H-------HHH---HHGGG--SS-------?HHHHHHHHHT?-----TTGGG??HH---H----HHHHHH-HHHHHHHHHHHHHH-H----HHHTT--------------------???HHH--HH------HHH----HHHHHHHHHH-H-HHH-HHHHHH-----------------------------HH---T?HHH-------HHHH-HHHHH----HHHHHHH--HH??----------------SSS???-------HHHH--HHH-----HHHHHH-------HHHHHHH 2CJ8|A PF04045.9_P34-Arc_seed 27 284 !Q:0,0|5,5|16,21|35,42|44,46|54,56|59,60|62,69|100,117|125,125|129,130|133,134|136,137|143,143|154,155|173,185|190,190|194,195|197,199|201,216|229,230|279,283 Q:1,4|6,15|22,34|43,43|47,53|57,58|61,61|70,99|118,124|126,128|131,132|135,135|138,142|144,153|156,172|186,189|191,193|196,196|200,200|217,228|231,278 ?EEEE?SSHHHHHTTT------HHHHHHHHSTTTE--------E???TTSSEEE???TT--S???--???SHHHHHHHHHTHHHHHTSHHHHHHHTHHHH??????????????--??HHHHTTT?EEE??SS--S??EEEEE?SSEEEEEEEE??SSSSHHHHHHHHHHHHH???????-?????EEEE?SSS??S???S?????------?????EEEEEEEEGGGG?-TTTHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSS????? 2P9I|D PF04049.8_APC8_seed 26 249 !Q:0,11|31,31|39,46|54,104|111,121|126,126|140,140|151,199|220,244 Q:12,30|32,38|47,53|105,110|122,125|127,139|141,150|200,219|245,248 ??----------HHHHHHHHHHHHHHHHHTT?HHHHHHH--------HHHHHTS????????--------------------------?????????????????HHHHHH-----------HHTH-HHHHHHHHHHHTT?HHHHHHHTTT??-----------------------------------------------SHHHHHHHHHHHHHHHHHHH?????????????-------?????TTHH 3ZN3|A PF04050.9_Upf2_seed 16 219 !Q:0,27|29,71|73,74|77,77|91,108|114,166|174,182|198,218 Q:28,28|72,72|75,76|78,90|109,113|167,173|183,197 ---------??-----------------S-------------------------------------------S??HH-HHHHHHHHHHHHH------------------HHHHT?????????????????????????-------????????------???????EEEEEEE??-??????EEEEEEESSSHHHHH?-------------------- 2WJV|D PF04051.11_TRAPP_seed 84 456 !Q:15,17|19,26|34,106|118,123|129,162|164,231|235,237|257,258|261,287|291,291|294,296|298,314|316,316|319,319|325,325|328,358|360,360|363,371|374,399|419,422|426,429|431,439|441,441|444,444|449,452|454,454 Q:0,14|18,18|27,33|107,117|124,128|163,163|232,234|238,256|259,260|288,290|292,293|297,297|315,315|317,318|320,324|326,327|359,359|361,362|372,373|400,418|423,425|430,430|440,440|442,443|445,448|453,453|455,455 HHHHHHHHHHHHHHH---H?-------SSHHHHH-------------------------------------------------------------------------HHHHHHHHHHH------HHHHH----------------------------------H????????????????????????????????????????????????????????????????????SSS???HHHHHHHHHHHHHHHTTSS??SE---------------------------EEE?SS--?S-----------------S?EE-EEESS?SS-------------------------------S?SS--------?TT---??---------------------HHHHHHHHHHHHHHHHHTS????EEE????S---------S?TT?EEEE????H-H 2J3T|A PF04052.8_TolB_N_seed 174 126 !Q:0,12|18,20|22,24|26,26|30,37|39,39|42,42|60,61|65,65|67,70|72,75|79,80|89,90|99,99|101,101|105,106|117,117|123,123 Q:13,17|21,21|25,25|27,29|38,38|40,41|43,59|62,64|66,66|71,71|76,78|81,88|91,98|100,100|102,104|107,116|118,122|124,125 ???????-?????EEEEE???E---E?SSS--------S?SS?HHHHHHHHHHHTSSEEE??GGG?S????S----TTS??HHHHHTTT??EEEEEEEE-E?TTS--EEEEEEEEEE?SSSTT?EE 3IAX|A PF04053.9_Coatomer_WDAD_seed 60 599 !Q:2,2|8,9|11,20|24,24|26,29|33,35|38,45|51,51|53,55|63,68|79,91|103,103|109,109|111,112|116,118|123,123|125,125|127,128|133,133|137,137|140,140|143,147|150,152|156,161|172,172|178,178|182,183|190,190|192,195|197,199|205,205|208,208|211,211|218,220|223,242|244,244|251,251|253,253|261,264|267,267|270,277|283,283|294,296|298,299|307,307|309,310|316,316|319,320|326,327|339,339|342,343|351,351|360,361|364,365|371,372|386,386|390,417|424,427|430,432|448,448|456,458|471,471|482,488|491,500|514,514|527,529|542,542|558,558|570,570|572,572|585,585|598,598 Q:0,1|3,7|10,10|21,23|25,25|30,32|36,37|46,50|52,52|56,62|69,78|92,102|104,108|110,110|113,115|119,122|124,124|126,126|129,132|134,136|138,139|141,142|148,149|153,155|162,171|173,177|179,181|184,189|191,191|196,196|200,204|206,207|209,210|212,217|221,222|243,243|245,250|252,252|254,260|265,266|268,269|278,282|284,293|297,297|300,306|308,308|311,315|317,318|321,325|328,338|340,341|344,350|352,359|362,363|366,370|373,385|387,389|418,423|428,429|433,447|449,455|459,470|472,481|489,490|501,513|515,526|530,541|543,557|559,569|571,571|573,584|586,597 TT?EEEEE??S???-----??SSS?B????EEE???SS?------?SEEEE?T---TSSEEEE------EETTEEEEEE-------------TTTTEEEEEEE?SEEEE?T--TSS?--EEEE?T-T??EEEE-ETT-EE?TT?????SS???EEE?-----SSSEEEEETT-EEEEE?TTT??EEEEES-S?---E---EEEEE?TT-SS-EEEEEE???SS---------?----------S?SEEEEE-E?HHHHHHH----HH-HT------??BTTTB?TTTEEEEEEE--?S??SEEEEET-T--EEEEE?TT--SEEEE--EETTEEEEEEE?SS??EEEEEEG-GGTEEEEE?-TT??EEEEE??HHHHHHHHHHHTT?HHH----------------------------HHHHTG----GG???HHHHHHHHHHHHHTT?HHHHHHH???HHHHHHHHHHHT?HHHHHHHHTT??----?HH----------HHHHHHHHHHHTT?HHHHHHHHHHHT--?HHHHHHHHHHTT?HHHHHHHHHHHHHTT?HHHHHHHHHHH-T?HHHHHHHHHHTT?HHHHHHHHHHTT? 2YNP|A PF04054.10_Not1_seed 30 412 !Q:7,12|15,15|17,18|26,30|44,44|48,48|61,61|100,103|124,124|140,140|143,143|153,156|159,163|167,169|171,171|181,185|187,190|195,195|197,198|211,214|225,226|228,231|233,241|244,245|247,247|249,255|279,281|302,302|317,318|337,343|345,345|367,369|382,382|384,384|387,387|397,398|405,411 Q:0,6|13,14|16,16|19,25|31,43|45,47|49,60|62,99|104,123|125,139|141,142|144,152|157,158|164,166|170,170|172,180|186,186|191,194|196,196|199,210|215,224|227,227|232,232|242,243|246,246|248,248|256,278|282,301|303,316|319,336|344,344|346,366|370,381|383,383|385,386|388,396|399,404 HHHHHHT------SS?H--HHHHTHH-----HHHHHHHHHHHHT?TTT?GGGHHHHHHHHS?HHHHHHHHTTSGGGTTHHHHHHHHHHHHHHHHHHHHSS?-??HHHHHHHHHHHHHHHHHHHH?HHHHHHTHHHHHHHS?TT?HHHHHHHHT???-TT?????SSS???S-SSSHHHHTS?????S--??TTTS?H--HHHHHHHHHHHH???-SHHHHHHHHH--T????S---------SS??S?H-------HHHHHHHHHHHHHHHHHHHHHTS???TTTSSSSHHHHHHHHHHHSS?HHHHHHHHHHHHTT??SSSHHHHHHHHHHHHHHH-------T?SSHHHHHHHHHHHHHHHHSSS???HHHHHHHHHHHH?T-TS?GGGSTGGGS?-HHHHHH??????? 4C0D|A PF04055.16_Radical_SAM_seed 628 438 !Q:2,3|5,6|8,15|20,20|25,81|84,88|93,94|106,107|112,116|122,142|145,145|150,181|194,194|196,254|256,257|264,264|269,296|308,320|326,326|328,328|333,356|364,365|367,369|371,378|393,399|401,411|419,419|424,424|426,427 Q:0,1|4,4|7,7|16,19|21,24|82,83|89,92|95,105|108,111|117,121|143,144|146,149|182,193|195,195|255,255|258,263|265,268|297,307|321,325|327,327|329,332|357,363|366,366|370,370|379,392|400,400|412,418|420,423|425,425|428,437 EE??S??S??-----?TTTS?TTTS?--------------------------------------------------------TT?????GGGS??HHHHHHHHHHH--HHTT--??-EEEEE---------------------SS?GGGS--------------------------------TTHHHHHHHHHT?T-----------------------------------------------------------T??EEEEEE?STTH----------------------------HHHHHHHHHTT-----------??EEEEE?S?SSHH------------------------HHHHHHS--S???H--------HHHHHHHHHHHHHT------?E-----------EEEEEEE?TTTT-G--GGHHHHHHHH 4JY9|A PF04057.7_Rep-A_N_seed 11 116 !Q:0,1|11,13|15,17|19,25|36,42|46,47|55,55|60,60|67,67|80,80|83,83|95,95|98,100|102,102|115,115 Q:2,10|14,14|18,18|26,35|43,45|48,54|56,59|61,66|68,79|81,82|84,94|96,97|101,101|103,114 ??TTHHHHHHH---H???S?----??EEEEEEEEEE??-----TTS??EEEEEEE?SSEE-EEEEEE?GGGHHHHHTTSS?TT?EEEEEEEEEEE?SS---S?EEEEEEEEEEEE? 2B29|A PF04060.8_FeS_seed 19 35 !Q:2,7|27,27|31,34 Q:0,1|8,26|28,30 TS??????TTSSSSHHHHHHHHHHTSS?SSS???? 4DJF|C PF04062.9_P21-Arc_seed 29 229 !Q:0,9|12,21|24,25|27,28|32,34|36,37|40,40|43,44|46,63|66,67|82,82|84,88|110,114|117,117|134,138|144,144|146,147|153,156|186,188|191,208|210,210|212,212|221,222|226,227 Q:10,11|22,23|26,26|29,31|35,35|38,39|41,42|45,45|64,65|68,81|83,83|89,109|115,116|118,133|139,143|145,145|148,152|157,185|189,190|209,209|211,211|213,220|223,225|228,228 ??????????TT--------??EE--T--TEE???B??SS?SS??B----------------??SS??HHHHHHHHHHHHTT?S?????SHHHHHHHHHHHHHHHHHHHH-----TT?SSHHHHHHHHHHHHHS-????TTSTT?T--TTTTS???-SSHHHHHHHHHHHHHHHHHHHHHHHHHHB?--SS-?----------------S?B?HHHHGGGG??GGG??S 2P9I|E PF04068.10_RLI_seed 80 44 !Q:6,6|9,12|14,16|21,21|23,23|29,29|32,37|42,43 Q:0,5|7,8|13,13|17,20|22,22|24,28|30,31|38,41 EEEEEE?SS----S??-HHHH?S-HHHHH?HH------HHHT?? 3J16|B PF04069.7_OpuAC_seed 87 386 !Q:0,0|5,7|9,9|28,28|30,30|35,37|39,39|44,44|50,50|53,54|62,62|74,82|85,86|97,97|104,105|110,110|116,117|129,138|140,140|143,147|153,161|167,171|173,176|181,181|189,189|194,200|207,219|225,226|228,231|243,244|253,253|260,263|265,265|269,269|271,305|307,309|311,312|314,321|328,329|335,335|338,339|350,353|367,367|369,371|373,374|377,377 Q:1,4|8,8|10,27|29,29|31,34|38,38|40,43|45,49|51,52|55,61|63,73|83,84|87,96|98,103|106,109|111,115|118,128|139,139|141,142|148,152|162,166|172,172|177,180|182,188|190,193|201,206|220,224|227,227|232,242|245,252|254,259|264,264|266,268|270,270|306,306|310,310|313,313|322,327|330,334|336,337|340,349|354,366|368,368|372,372|375,376|378,385 ?EEEE???S-SHHHHHHHHHHHHHHHTT-T?EEEE???S?SHHH-HHHHH-HT--TSSSEEE-EEHHHHHHTTS???----??SS??HHHHHHHHHH-HHHHHH??EEEE-EEEEE??EEEEEEHHHHH----------H-HT?---?BGGGG---------TTTGG-----G?---EEEE?TTTTTST-TSHH-------HHHHHH-??------??--SEEEE??G----GGHHHHHHTTS-?SBEEEETT?THHHHT----T-EEE?B----------------------------------?T---T??S??-----?EEEEEE?-HHHHT?HH--HHHHHGGGTT??-?HHHHHHHHHHHHT-S???H--HH-HHHHHHHH 3MAM|A PF04072.9_LCM_seed 211 268 !Q:14,14|16,18|20,20|23,24|43,71|85,87|90,90|105,105|107,107|110,114|121,121|124,125|131,133|135,143|145,145|152,152|168,170|172,190|192,193|197,197|199,200|203,204|207,208|210,211|219,220|222,224|228,241|247,247|249,250|255,255 Q:0,13|15,15|19,19|21,22|25,42|72,84|88,89|91,104|106,106|108,109|115,120|122,123|126,130|134,134|144,144|146,151|153,167|171,171|191,191|194,196|198,198|201,202|205,206|209,209|212,218|221,221|225,227|242,246|248,248|251,254|256,267 HHHHHHHHHHHHTS-T---T?SS??TTHHHHHHTTSTHHHHHH---------------??????????????HHHHHHHHHHHHH---HH-HHHHHHHHHHHHHH-H-TT---??EEEEET?TT??HHHHS???T---------T?EEEEEE?HHHHHHHHHHHHHTT???S-------------------S--EEE-E--EE??TT--S??HHHHHHT--T??-TTS----------?---EEEEE?S-?GGGS?HHHHHHHHHHHH 2ZZK|A PF04073.10_tRNA_edit_seed 91 179 !Q:0,0|3,4|7,7|16,26|31,32|40,60|63,66|76,77|79,79|89,92|94,96|99,102|111,111|113,116|118,118|122,123|126,135|138,141|153,156|161,161|171,171 Q:1,2|5,6|8,15|27,30|33,39|61,62|67,75|78,78|80,88|93,93|97,98|103,110|112,112|117,117|119,121|124,125|136,137|142,152|157,160|162,170|172,178 ?TT??SH-HHHHHHHT---------??GGGE--EEEEEEE--------------------?SS?---EEEEEEETT??B?HHHHHHHHT----S-??EE?--?HHHHHHHH-S----S?TTS??SS??--------SS??-?EEEEGGGGGSS-?--EEEE?SSTTEEEEE?HHHHHHH 3RIJ|A PF04074.7_DUF386_seed 13 157 !Q:0,1|15,16|30,30|34,35|41,41|43,43|46,46|52,62|66,66|79,79|85,86|88,92|97,99|110,111|114,114|120,120|128,128|131,132|138,146 Q:2,14|17,29|31,33|36,40|42,42|44,45|47,51|63,65|67,78|80,84|87,87|93,96|100,109|112,113|115,119|121,127|129,130|133,137|147,156 ?-EEEETTSTTTTTT??HHHHHHHHHHHHS?GGG??SEEEE?S-SS?EEEEE???????????EEE?SSEEEEEEEEES?EEEEE??S??--?GGGS???BTTTTBEEES??TT?EEEEE?TTEEEEE?TT??EEEEE?????????EEEEEEEEGG 1JOP|A PF04075.9_DUF385_seed 10 150 !Q:0,19|22,22|25,26|28,32|39,39|43,43|51,52|61,62|67,67|69,70|74,74|76,76|85,86|102,102|105,108|123,123|126,129|135,135|138,138|140,143|149,149 Q:20,21|23,24|27,27|33,38|40,42|44,50|53,60|63,66|68,68|71,73|75,75|77,84|87,101|103,104|109,122|124,125|130,134|136,137|139,139|144,148 ?------------???????TT?TT--S-??-?EEEEEE?TTT?SEEEEEE--EEEEETTE--EEEE?S??GGG?S?HHHHHHHH??EEEEEETTEEEEEEE-EE??--HHHHHHHHHHHHHH?TT-???TTGGG?TT-S?---EEEEE? 3R5R|A PF04076.8_BOF_seed 7 109 !Q:0,5|7,27|35,35|63,63|69,70|77,80|84,84|93,93 Q:6,6|28,34|36,62|64,68|71,76|81,83|85,92|94,108 ???---S???????????????-?????HHHHTTS?SSEEEEEEEEEEEEEETTEEEEEETTE-EEEEE??GGGSTT????TTS?EEEEEEEE-EETTEEEEEEEEEEE 1NNX|A PF04077.7_DsrH_seed 66 110 !Q:1,1|15,20|23,23|28,28|34,34|51,51|68,69|74,74|77,86|89,89|91,91|95,96|104,104 Q:0,0|2,14|21,22|24,27|29,33|35,50|52,67|70,73|75,76|87,88|90,90|92,94|97,103|105,109 S?TTTBTHHHHHHHH?----?TT?EEEE?GGGGG-GGBTTSTTHHHHHHHT-TTSEEEEEHHHHHHTT??GGGB?TT?---------EE-E?HHH--HHHHHHH-SSEEE 2HYB|C PF04078.8_Rcd1_seed 27 324 !Q:7,7|12,13|28,28|58,66|69,71|73,74|93,94|116,119|123,124|142,142|144,145|148,151|173,173|216,218|222,224|228,230|232,239|257,276|287,287|292,293|304,306|321,323 Q:0,6|8,11|14,27|29,57|67,68|72,72|75,92|95,115|120,122|125,141|143,143|146,147|152,172|174,215|219,221|225,227|231,231|240,256|277,286|288,291|294,303|307,320 HHHHHTS-STTT--HHHHHHHHHHHTTT?TTHHHHHHHSTTHHHHHHHHHHHTGGGBT---------TB???H--HHHHHHHHHHHHHHHHHH-?TTTHHHHHHTTGGGGTHHHHH????SHH--HHHHHHHHHHHHHHHGG-G??HH----HHHHHHHTTHHHHHHHHHHHS?HHHHHHHHHHHHHHHHSHHHHHHHTSSHHHHHHHHHHHHHHH---HHT---TTS?-?H--------HHHHHHHHHHHHHTTSH--------------------HHHHHHHHHS?GGGT--SSTTHHHHTS--?HHHHHHHHHHHHHS-?? 2FV2|A PF04079.11_DUF387_seed 139 209 !Q:12,14|16,16|27,28|30,34|36,41|57,74|79,80|88,88|97,97|111,111|114,116|133,134|137,137|146,147|149,151|170,170|173,173|176,177|180,180|184,184|193,193|196,197|202,208 Q:0,11|15,15|17,26|29,29|35,35|42,56|75,78|81,87|89,96|98,110|112,113|117,132|135,136|138,145|148,148|152,169|171,172|174,175|178,179|181,183|185,192|194,195|198,201 HHHHHHHHHHTT---T?EEHHHHHHHH--T-----S--?---HHHHHHHHHHHHHHT------------------TSTT?-SEEEEES-SSEEEEEE?GGGHHHHHHHHHS-SS-??TTHHHHHHHHHHHHHH?-SB?HHHHHHHH-?S?-?HHHHHHHHHTTSEEEEEE?SS-TT??EE-EEE?HHHHHHTT?SS--GGGS?----?? 3W6J|B PF04083.11_Abhydro_lipase_seed 82 105 !Q:9,11|18,18|30,30|32,32|35,73|76,82|84,86|91,92|95,96|104,104 Q:0,8|12,17|19,29|31,31|33,34|74,75|83,83|87,90|93,94|97,103 HHHHHHHTT???EEEEEE?TTSBEEEEEEE?S?SS---------------------------------------TT???????E---EEEE??TT??GGGGGSS? 1K8Q|A PF04085.9_MreC_seed 20 243 !Q:5,8|12,12|18,21|26,32|35,35|40,43|47,47|53,54|58,58|61,61|69,69|72,74|76,77|83,84|88,139|154,160|167,168|170,177|180,180|186,187|189,194|197,198|214,214|217,220|228,230|233,234|242,242 Q:0,4|9,11|13,17|22,25|33,34|36,39|44,46|48,52|55,57|59,60|62,68|70,71|75,75|78,82|85,87|140,153|161,166|169,169|178,179|181,185|188,188|195,196|199,213|215,216|221,227|231,232|235,241 EEEEE-???TTS?EEEES--??GGGT?-----?TT?EEEE----TTE-EEEEE--EEE?SS?EEEEETT?SB??-S??EEEEE--ETT----------------------------------------------------EEEEEEEEEEETTT-------TEEEEE??S--??????TT?EEEEE??S------SS??EEEEEEEEEEEESTT?SS?--?EEEEEES???TT??EEEEEEE? 2QF4|A PF04086.8_SRP-alpha_N_seed 27 362 !Q:0,1|14,44|64,64|87,104|119,126|130,130|143,361 Q:2,13|45,63|65,86|105,118|127,129|131,142 ??HHHHHHHHTGGG???-------------????-????----??EEEEEEETTTTEEEEEEES?GGGHHHHHHHHHHHHHHHHHHT------------------HHHHHSSSTHHHHS???---??HHH-HHHHHHHHHHHT?--????????????????????????????????----------------------------------------------------------------------------------??????---------?---??---------------------------------------------------------??????------------------ 2FH5|A PF04089.9_BRICHOS_seed 40 107 !Q:26,26|32,33|36,39|52,52|54,90|94,94|102,102|106,106 Q:0,25|27,31|34,35|40,51|53,53|91,93|95,101|103,105 EEETTTEEEEEETTTTEEEEESSTTS?EEEEE??TT????HHHHHHHHHHTT?S??????????????????????--?????????????HHH-HHHHTTS?EEE? 2YAD|A PF04091.7_Sec15_seed 31 410 !Q:4,4|10,34|50,59|74,76|83,83|97,100|111,111|113,114|117,117|148,171|173,175|196,196|199,200|203,213|215,224|247,247|269,269|272,280|300,333|338,345|365,409 Q:0,3|5,9|35,49|60,73|77,82|84,96|101,110|112,112|115,116|118,147|172,172|176,195|197,198|201,202|214,214|225,246|248,268|270,271|281,299|334,337|346,364 HHHH-HHTTS???-------????????---????SSSBTHHHHHHHHHH----------HHHHHHHHHHHHTT?-?HHHHHH-HHHHHHHHHHHHH----HHHHHHHHHT?T--TS?HHHHHHHHHHHHHHHTTHHHHHHHHHHHHT????-??-----------??????S???TTHHHHHHHHHHHHHHHHHH-TT??TT-???-?????-S--------??HHHHHHHHHHHHHHHTTTTTSH-HHHHHHHHHHHHHHHHHHHHH-HT?????????TTHHHHHHHHHHHHHHHTT?---------------------------------SSSS??------SSTTGGGGHHHHHHHHHHH?????-??------------------------------------- 2A2F|X PF04092.8_SAG_seed 58 196 !Q:6,18|23,23|26,26|35,35|37,37|43,44|49,52|57,58|63,84|88,88|92,93|97,98|100,100|107,109|112,113|116,117|122,127|130,130|137,137|139,140|145,145|148,149|159,188|196,196 Q:0,5|19,22|24,25|27,34|36,36|38,42|45,48|53,56|59,62|85,87|89,91|94,96|99,99|101,106|110,111|114,115|118,121|128,129|131,136|138,138|141,144|146,147|150,158|189,195 TTTEEE?----------??STTT?SS?EEEEEBTT-B?EEEEE??TTEE----EEST--TTTT----------------------EEE?GGG??TTS??E-EEGGGT?--TT??GG--GEEE?-----SS?TTEEEE-E??GGGS?SS?-EEEEEEEEE????----???????---????????????EEEEEEE- 2WNK|A PF04095.11_NAPRTase_seed 19 321 !Q:5,6|12,12|22,32|38,39|42,42|55,56|60,60|62,62|64,66|68,69|77,77|93,93|96,98|103,104|107,107|115,116|129,130|133,134|136,147|152,153|156,156|164,176|186,193|196,198|206,206|209,210|227,227|243,244|266,270|273,273|276,276|278,281|284,284|289,289|293,293|298,298|305,305|308,308|310,310|312,312 Q:0,4|7,11|13,21|33,37|40,41|43,54|57,59|61,61|63,63|67,67|70,76|78,92|94,95|99,102|105,106|108,114|117,128|131,132|135,135|148,151|154,155|157,163|177,185|194,195|199,205|207,208|211,226|228,242|245,265|271,272|274,275|277,277|282,283|285,288|290,292|294,297|299,304|306,307|309,309|311,311|313,320 GSEEE??TTTSS?HHHHHHHHH-----------HHTTT??BB?BTHHHHHHHHHT??SSS?S?B???B??THHHHTT?GGGHHHHHHHHHHHT?SS?--EEEE??SS?HHHHHHT--IIIIITHHHHHT??TT--S?-----------EEEE??SS?HHHHHHH-------------HHHHHHHHS????????SB???TTEEEEE?SS??HHHHHHHHHHHHHTTB?GGGEEEEESHHHHTS??TTTTTEEEEEEEEEETTEEEE?????TT?GG-G????SS?EEEE?TTS?EEEE?TTGGGS?TT?S?S?EEEEETTE 2GVG|A PF04096.9_Nucleoporin2_seed 57 171 !Q:0,0|6,6|14,14|21,23|27,27|32,32|42,43|45,45|47,48|53,53|55,55|58,64|83,85|88,90|93,96|102,102|104,104|112,128|131,131|134,135|147,148|169,170 Q:1,5|7,13|15,20|24,26|28,31|33,41|44,44|46,46|49,52|54,54|56,57|65,82|86,87|91,92|97,101|103,103|105,111|129,130|132,133|136,146|149,168 ?EEEES?HHHHTTS?HHHHTS---BSS?EEEE-TTTEEEEES--S?B??GGGT-T?HH-------HHHBTTTEEEETTTEEEE-??SG---GG-???TTSTT?S?EEEEESS????---??????????TT?HH--HHHHHHHHHHH-?SSSEEEEEETTTTEEEEEES?? 2AIV|A PF04097.9_Nic96_seed 40 842 !Q:0,0|25,29|41,42|60,85|89,91|117,122|124,124|126,126|141,141|145,145|151,154|157,159|176,176|185,185|192,198|206,248|259,263|266,267|269,272|275,280|282,282|285,286|299,321|331,331|334,334|341,352|362,362|373,377|379,379|395,430|441,441|447,447|462,478|483,483|494,498|503,506|512,513|516,516|518,518|521,521|523,524|526,527|532,537|539,539|544,544|546,546|562,563|569,569|582,596|616,616|620,620|622,652|654,654|657,658|662,662|677,677|684,685|687,687|694,694|712,712|725,726|728,749|759,760|762,762|792,794|798,813|829,830|841,841 Q:1,24|30,40|43,59|86,88|92,116|123,123|125,125|127,140|142,144|146,150|155,156|160,175|177,184|186,191|199,205|249,258|264,265|268,268|273,274|281,281|283,284|287,298|322,330|332,333|335,340|353,361|363,372|378,378|380,394|431,440|442,446|448,461|479,482|484,493|499,502|507,511|514,515|517,517|519,520|522,522|525,525|528,531|538,538|540,543|545,545|547,561|564,568|570,581|597,615|617,619|621,621|653,653|655,656|659,661|663,676|678,683|686,686|688,693|695,711|713,724|727,727|750,758|761,761|763,791|795,797|814,828|831,840 ?HHHHHHHHHHHHHHHHHHHHHHTT??-??HHHHHHHHHHT??SHHHHHHHHHHHHHHTT--------------------------TTS???HHHHHHHHHHHHHHHHHHHHHHHHT??----S?S?HHHHHHHHHHHSSB?SSS?BSSTT??--EE---TTEEHHHHHHHHHTTT?HHHHHHHH-HHTGGG???????HHHHHHH???????????????????????????????-----------?HHHHHHHHHH-----HT??G----GG?---??G-GG??SHHHHHHHHHHT?????---????----???????HHHHHHHHH-HH?GGGGTT-----------?HHHHHHHTT?HHHHHHHHHT-----T?HHHHHHHHHHHHHTT???????-------------??????????----??HHHHHHHHHT-TTTTT?HHHHHHHHHGGGGS??---------------HHHH-HHHHHHHHHH-----HHHH?--?HHHHH?-EE?T-TS?E--E??HHHH------T?GGGT?S?HHHHHHHHHHHHHHH--HHHTT?HHHHHHHHHHTT--------------?HHHHHHHHHHHHHHHHHHS?TTS?S-------------------------------S?SS??TTT?HHHHHHHHHHHHTT?HHHHTT--S?HHHHHH-HHHHHHHHHHHHHHHTT?HHHHHHHHHHTS-?S??------------?????--?HHHHHHGGG--S?HHHHTTHHHHHHHHHHHHHHHHHHHHSTT???TTH----------------HHHHHHHHHHHHHHH--HHHHHTGGGS? 2QX5|A PF04098.10_Rad52_Rad22_seed 35 206 !Q:10,11|13,13|22,22|26,27|29,36|41,41|54,54|69,84|92,112|130,134|145,145|147,147|149,149|173,173|175,175|184,184|191,192|197,205 Q:0,9|12,12|14,21|23,25|28,28|37,40|42,53|55,68|85,91|113,129|135,144|146,146|148,148|150,172|174,174|176,183|185,190|193,196 HHHHHHHHTT??B?TTTEEEEE?SSS-?E--------EEEE?HHHHHHHHHHHH?TTTEEEEEEEEEEE----------------EEEEETT---------------------EEEEEEEEEEEEEETTS?----EEEEEEEEEE?S?S?HHHHHHHHHHHHHHHHHHHHHHT-T?GGGTTSTT?HHHHHH--HHTS???--???? 1KN0|A PF04099.7_Sybindin_seed 11 234 !Q:7,7|11,11|18,24|30,30|33,33|40,40|49,51|54,55|58,58|68,68|73,73|79,81|88,88|92,92|100,104|126,126|128,139|143,155|157,157|165,165|172,172|176,176|183,183|186,189|208,208|211,212|216,219 Q:0,6|8,10|12,17|25,29|31,32|34,39|41,48|52,53|56,57|59,67|69,72|74,78|82,87|89,91|93,99|105,125|127,127|140,142|156,156|158,164|166,171|173,175|177,182|184,185|190,207|209,210|213,215|220,233 EEEEEEE?TTS?EEEEEE???????EEEEE?SS?SSEEEE?SSSEEEEE???TT??TT?EEEEETTEE?BTTB?TTSSB---HHHHTT?GGG?SEEEEEE?????HHHHHHHHHHHHHHHHHHHHT?S------------SSS?-----------?S?SEEEESS?EEEEEE?TTS?EEEEEE?TT?-??HHHHHHHHHHHHHHHHTT?TT??TTS????HHHHHHHHHHHHHH 2J3T|C PF04101.11_Glyco_tran_28_C_seed 34 224 !Q:0,0|6,6|10,10|32,33|37,48|54,55|68,68|73,76|81,83|86,86|103,104|115,115|123,123|135,136|141,142|145,149|151,151|161,161|173,173|175,176|192,203|206,213 Q:1,5|7,9|11,31|34,36|49,53|56,67|69,72|77,80|84,85|87,102|105,114|116,122|124,134|137,140|143,144|150,150|152,160|162,172|174,174|177,191|204,205|214,223 ?EEEEE?SSS?HHHHHTTSSSHHHHHHHHHHT??EEE------------EEESS??HHHHHHHHHTTT?EEEE????TTTT???TT?EEEEEGGGTEEEEEEE??SSHHHHHHHH?SEEEEES?SHHHHHHHHTT??EEEE??TT-----S?HHHHHHHHH-HHHHHTSEEEE?S--STTHHHHHHHHHHHS???---??????HH--------HHHHHIIIII 3H4I|A PF04102.7_SlyX_seed 114 74 !Q:47,73 Q:0,46 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?????-????--??????---?????? 3EFG|A PF04104.9_DNA_primase_lrg_seed 48 428 !Q:0,73|75,81|84,89|95,135|137,142|146,146|157,159|164,166|179,201|205,206|208,213|228,232|234,235|242,242|246,247|255,287|296,299|302,308|310,313|316,317|320,325|327,327|337,345|349,353|360,376|385,385|400,412|414,416|418,422 Q:74,74|82,83|90,94|136,136|143,145|147,156|160,163|167,178|202,204|207,207|214,227|233,233|236,241|243,245|248,254|288,295|300,301|309,309|314,315|318,319|326,326|328,336|346,348|354,359|377,384|386,399|413,413|417,417|423,427 -------------------?--------?????----------------------------------------?G-------GG------HHHHH-----------------------------------------H------HTS?HHHHHHHHHH---HHHS???HHHHHHHHHHHH-----------------------HTT??H------HHHHHHHHHHHHTT-----T??HHHHHH-HTH--HHHHHHT?----------???????-----?????-----HHHHHHSS??-?TT----???S---?HH--HH------S?HHHHHHHHH---------HTT---??HHHHHH-----------------HHHHHHTT?HHHHHHHHHHHHHT?------------S???S??-??HHHHH 3L9Q|A PF04106.7_APG5_seed 34 397 !Q:3,3|16,16|18,73|84,89|93,98|100,109|131,138|145,145|159,160|162,162|175,202|208,208|211,212|217,217|221,237|241,241|243,247|250,266|270,270|272,273|283,284|287,353|362,364|366,367|379,380|384,384|386,389|396,397 Q:0,2|4,15|17,17|74,83|90,92|99,99|110,130|139,144|146,158|161,161|163,174|203,207|209,210|213,216|218,220|238,240|242,242|248,249|267,269|271,271|274,282|285,286|354,361|365,365|368,378|381,383|385,385|390,395 TTS?HHHHHHHHTTTS?S--------------------------------------------------------SEEEEEESSS----??TTT??????H----------HHHHHHHHHHHHHHHHHHHTT--------TTTTTS?HHHHHHHHHHHHT--T?HHHHHHHHGGGG?-------------------------??TTSSS?SS??EEEE?TTS-----------------SSS?B?????SB?----------------SSS?B?-BHHHHHHHH??TT?------------------------------------------------????----------????EEEEBTTB???T--TSBHHHHHHHS??TTS?E----EEEEEE?- 3W1S|A PF04107.8_GCS2_seed 12 326 !Q:17,19|21,22|33,33|35,37|44,44|54,56|84,84|88,89|92,92|95,115|118,121|123,123|125,125|127,128|130,130|138,138|146,151|169,170|172,172|179,179|181,181|184,184|195,197|200,203|209,209|223,223|228,242|244,246|253,253|257,260|269,275|299,304|311,312 Q:0,16|20,20|23,32|34,34|38,43|45,53|57,83|85,87|90,91|93,94|116,117|122,122|124,124|126,126|129,129|131,137|139,145|152,168|171,171|173,178|180,180|182,183|185,194|198,199|204,208|210,222|224,227|243,243|247,252|254,256|261,268|276,298|305,310|313,325 EEEEEEEEEEETTTTEE?--S??HHHHTTTSSS?S---SSEEEE?SSSSEEEEE??-SBSSHHHHHHHHHHHHHHHHHHHHHTT?EEE??SB?SS?????????????????????GG----G-G?S??B?EEEEEEE?SSHHHHH------HHHHHHHTTHHHHHHHH??B?EETTEE?S?SB?GGGGGTTSTT--?SS????SSHHH-HHHHHHHHTTSSS?SSGG---------------G???SEEEET-TTT----EEEEEEEE??-----SSHHHHHHHHHHHHHHHHHHHHH??????GGGGTT--HHHHHHHHHHHGG 1TT4|A PF04108.7_APG17_seed 19 498 !Q:41,41|104,122|126,128|135,136|143,146|157,158|181,183|194,195|198,218|229,231|254,302|305,306|376,380|398,406|432,432|444,445|483,483|487,487|494,497 Q:0,40|42,103|123,125|129,134|137,142|147,156|159,180|184,193|196,197|219,228|232,253|303,304|307,375|381,397|407,431|433,443|446,482|484,486|488,493 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHIIIIIIIIIIIIIIIIIIIITTHHHHHHHHHHHHHHHHHHHHHTS????---------------SSS???TTTTSS??TTTTHH----HHHHHHHHHH--HHHHHHHHHHHHHHHHHHHHHH---HHHHHHHHHH--HH???????????-----?????HHHHHHHHHH---HHHHHHHHHHHHHHHHHHHTTT-------------------------------------------------TS??SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----HHHHHHHHHHHHHHHHH---------HHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSS?GGG-STTTSS???? 4HPQ|C PF04110.8_APG12_seed 6 91 !Q:8,8|12,14|16,17|25,25|40,41|45,46|55,57|60,60|70,73|80,80|87,90 Q:0,7|9,11|15,15|18,24|26,39|42,44|47,54|58,59|61,69|74,79|81,86 EEEEEEEE?SSS???S??EEEEESS?BHHHHHHHHHHHTT??SSS??EEEETTTB???TT?BHHHHHHHH?---BTTEEE-EEEESS???? 3W1S|C PF04111.7_APG6_seed 99 533 !Q:0,177|192,198|201,203|207,211|213,213|215,215|220,221|227,235|240,242|266,271|273,273|275,275|280,283|287,287|294,335|338,339|343,352|354,359|361,364|368,374|392,395|400,402|404,465|467,467|469,471|476,477|483,483|488,489|494,494|496,497|500,501|504,504|528,532 Q:178,191|199,200|204,206|212,212|214,214|216,219|222,226|236,239|243,265|272,272|274,274|276,279|284,286|288,293|336,337|340,342|353,353|360,360|365,367|375,391|396,399|403,403|466,466|468,468|472,475|478,482|484,487|490,493|495,495|498,499|502,503|505,527 ----------------------------------------------------------------------------------------------?-------------------------------------?--------------??------------------------?????HHHHHHHHHHHHHT???????SS???EEE-----E-T-TEEE--ETTEE???------BTTB???HHHHHHHHHHHHHHHHHHHHHHT??---?S-S-EEEE?--?GGG?EEEESS--?---------------------------------------TT??EES------???-S------S?---GGG?-----?SHHHHHHHHHHHHHHHH----HHHH---H--------------????------?---------------------?---------?----?S-S--?EETT--TTEEE?TTTT??EEES?S--TT??HH-HHHHHHHHHHHHHHHHHHHHHHH??-?? 3Q8T|A PF04115.7_Ureidogly_hydro_seed 81 337 !Q:0,1|4,9|13,14|26,26|28,28|30,45|47,56|74,74|78,84|87,87|97,97|99,101|104,134|138,138|143,143|147,147|155,176|182,182|184,186|189,249|252,253|257,257|263,263|266,270|275,275|278,278|281,281|283,283|288,291|300,305|309,310|312,316|318,323|328,329|333,333 Q:2,3|10,12|15,25|27,27|29,29|46,46|57,73|75,77|85,86|88,96|98,98|102,103|135,137|139,142|144,146|148,154|177,181|183,183|187,188|250,251|254,256|258,262|264,265|271,274|276,277|279,280|282,282|284,287|292,299|306,308|311,311|317,317|324,327|330,332|334,336 ?-EE--??--EEE??HHHHTTTEEEE?S-T----------------T??-------?EEEGGGTEEEEEEEEEE?BSS-------TT?EEEEEEEEE-E???SS-------------------------------EEE?EEEE?TTB?EEEEESS?-??------------------EEEEE-E?--SS-------------------------------------------------------------SS??GGG?EEEEE?SS?----EEEE?TT?EE?S?EESS----SEEEEEEE------EEE-?S-----S?---??EEEE??GGG?EEE 2BDR|A PF04119.7_HSP9_HSP12_seed 24 73 !Q:0,2|4,6|9,22|32,33|36,36|58,59|62,64 Q:3,3|7,8|23,31|34,35|37,57|60,61|65,72 ???S???HH--------------HHHHHHHHS??SS?THHHHHHHHHHHHHHHHHHTS??SS???SHHHHTGG 2L9Q|A PF04121.8_Nup84_Nup100_seed 16 821 !Q:23,25|28,46|50,50|62,62|79,87|90,95|106,125|127,128|130,131|140,140|145,145|167,167|180,180|190,192|196,197|199,199|210,233|236,236|255,255|259,259|271,271|274,276|283,285|311,311|313,313|317,322|324,336|345,348|371,372|383,396|419,419|423,423|443,443|454,455|461,820 Q:0,22|26,27|47,49|51,61|63,78|88,89|96,105|126,126|129,129|132,139|141,144|146,166|168,179|181,189|193,195|198,198|200,209|234,235|237,254|256,258|260,270|272,273|277,282|286,310|312,312|314,316|323,323|337,344|349,370|373,382|397,418|420,422|424,442|444,453|456,460 HHHHHHHHHHHHHHHHHHHHHHH---HH??????????---------TTS?HHHHHHHHHHH?HHHHHHHHHHHHHHHT???--????SS??----SSTTHHHHHT--------------------S??S??STTHHHHS?GGGS?HHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHTT?HHHHHHHHT---TSB?-B?TTTSGGGTTT?-----------------------SS?BSBTTHHHHHHHHHHHHH?SSS?HHHHHHHHHHH-TS???HHHHTT?-?HHHHHHHHHHHHHHHHHHHHHHHTT?S?GGG?----?S???????-----?HHHHHHHH----HHHSHHHHHSTTHHHHHHHHSS??HHHHHHHHHT??????????????TTSHHHHHHHHHHHHHHHHHST-TSS?HHHHHHHHHHHHHHHHHTT?GGGHHHHHTT?-GGGGG???????????????????----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3CQG|A PF04126.8_Cyclophil_like_seed 14 129 !Q:0,1|8,12|19,21|25,25|36,36|52,53|55,59|62,63|65,68|87,88|91,92|96,99|108,109|111,115|119,120 Q:2,7|13,18|22,24|26,35|37,51|54,54|60,61|64,64|69,86|89,90|93,95|100,107|110,110|116,118|121,128 ??EEEEET-----TEEEEE???TTS?HHHHHHHHHT?SEEEEEEEETTEEEE??S?????SS??B????TTEEEEETTTTEEEEESS??TT?-TTS????SSEEEEEE??S??-??GGG??SSEEEEEE 2KA0|A PF04127.10_DFP_seed 702 328 !Q:3,4|6,7|9,10|17,17|30,32|48,48|53,53|55,58|60,61|63,83|85,85|87,90|92,92|96,97|109,109|112,114|116,121|124,130|133,133|137,138|140,141|144,145|148,151|154,155|157,157|159,181|184,191|193,194|199,201|205,209|212,212|214,219|221,221|224,234|236,241|243,243|246,247|253,254|256,256|258,265|272,274|280,284|288,288|296,296|301,307|310,311|315,315|318,320|325,325 Q:0,2|5,5|8,8|11,16|18,29|33,47|49,52|54,54|59,59|62,62|84,84|86,86|91,91|93,95|98,108|110,111|115,115|122,123|131,132|134,136|139,139|142,143|146,147|152,153|156,156|158,158|182,183|192,192|195,198|202,204|210,211|213,213|220,220|222,223|235,235|242,242|244,245|248,252|255,255|257,257|266,271|275,279|285,287|289,295|297,300|308,309|312,314|316,317|321,324|326,327 TTT-?E--E--EEEESB?EEESSSSEEEEE???SHHHHHHHHHHHHTT?EEEE-E----E-?S-?-?---??--?----?----T-T--?-E-EEE-?SSHHHHHHHHH-HH---G------GG?------SE-EEE??B??SE--EE----SS??S-S??---?-?---???-----????EE--------E--EEEE???HHH-----HH-H------T?SS-----------S?-?---E-EE--EEEEE--S-S--------SHHHHH---HHHHH-----HHT?SEEEEEE?SSSS-------SS--SSS-SE---EEEE-EE 1U80|A PF04130.8_Spc97_Spc98_seed 120 2100 !Q:2,7|12,12|15,17|19,21|29,52|57,58|60,76|80,80|86,98|115,116|124,159|161,161|178,178|183,183|195,239|242,244|254,255|271,277|279,331|336,337|350,351|353,355|357,364|369,369|371,374|388,390|393,425|432,433|436,467|469,474|477,496|502,573|577,583|586,623|626,664|668,669|673,675|689,694|696,701|704,704|708,881|894,894|897,898|906,1293|1303,1304|1311,1322|1328,1329|1332,1334|1337,1337|1345,1351|1354,1360|1378,1380|1400,1402|1414,1716|1726,1730|1738,1740|1743,1770|1780,1791|1802,1809|1814,1814|1822,1832|1837,1861|1870,1881|1901,1912|1915,1920|1929,1929|1936,2067|2069,2071|2075,2075|2077,2082|2087,2087 Q:0,1|8,11|13,14|18,18|22,28|53,56|59,59|77,79|81,85|99,114|117,123|160,160|162,177|179,182|184,194|240,241|245,253|256,270|278,278|332,335|338,349|352,352|356,356|365,368|370,370|375,387|391,392|426,431|434,435|468,468|475,476|497,501|574,576|584,585|624,625|665,667|670,672|676,688|695,695|702,703|705,707|882,893|895,896|899,905|1294,1302|1305,1310|1323,1327|1330,1331|1335,1336|1338,1344|1352,1353|1361,1377|1381,1399|1403,1413|1717,1725|1731,1737|1741,1742|1771,1779|1792,1801|1810,1813|1815,1821|1833,1836|1862,1869|1882,1900|1913,1914|1921,1928|1930,1935|2068,2068|2072,2074|2076,2076|2083,2086|2088,2099 HH------HHHH-TT???S---SSEEETT------------------------TEEE??S?---------------?TTS?HHHHH-------------HHHHHHHHHHHHHHHH--HHHHHTS?????????-------------------????????S?SHHHHHHHHHHHHHTH-HHHH-HHHHHHHHHHH?--------------------------------------------TT?-?HHHHHHHTH--HHHHHHHHHHHHHHH-------H-----------------------------------------------------HHHT??THHHHHHHHHHH--H---S-??-----HHHH-H----HHHHHHHHHHHHH---HH---------------------------------HHHHHH--HH?------?----??----?-------------T------TS---?----------------SSEEE???????????---??????????-???????????????????????????---------?----------EEE------?GG--------------------------------------GS----?----------------------------------TTS-?HHH---HHHHHHHHHHHHT??????S??????TT?SHH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHHHHHHHHHHT?SS??HHHHHHH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHHHHHHHH--HHHHHH------------HHHHS-?HH---HH-HHHHHHH-------TT?----??HHHHHHHHHHHHHHHSS???TTHHHHHHHHHHHHHHHTT???TTTGGGEEEEE?----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------????????????????????????????TTTTEEEEE???--TTGGGTS--?HH----------------------------HHHHHHHHH------------HHHHHHHHHH--------HHHH-HHHHHHT-----------SGGG-----------------------??SSHHHHHH------------HHHHHHHHHHHHHHHHHHH------------HH------THHHHHHH-HHHHHH------------------------------------------------------------------------------------------------------------------------------------T???HHH-H------HHHH-HHHHHHHHHHHH 3RIP|A PF04131.9_NanE_seed 7 201 !Q:12,12|30,31|33,33|38,38|40,42|46,48|51,51|64,64|71,72|75,76|79,81|93,93|96,96|102,102|116,116|121,121|131,134|138,139|151,154|160,162|174,175|181,181|186,186|199,200 Q:0,11|13,29|32,32|34,37|39,39|43,45|49,50|52,63|65,70|73,74|77,78|82,92|94,95|97,101|103,115|117,120|122,130|135,137|140,150|155,159|163,173|176,180|182,185|187,198 HHHHHHHHHHHT?SEEEEESHHHHHHHHTT??S?EEEE?B???TTS???BS?SHHHHHHHHTTT?SEEEEE??SS??TT???HHHHHHHHHHH?TT?EEEEE?SSHHHHHHHHHTT?SEEE?TTTTSSTTS?--?SSS??HHHHHHHHHTT??--EEEES???SHHHHHHHHTT??SEEEE?HHHH?HHHHHHHHHHHT?? 3Q58|A PF04135.7_Nop10p_seed 44 60 !Q:0,4|7,7|11,18|23,23|26,26|30,31|33,33|38,42|45,45 Q:5,6|8,10|19,22|24,25|27,29|32,32|34,37|43,44|46,59 ?????EE?TTT?------?EESS-SB?TTT??B?EESS?????SS?TTHHHHHHHHHHHH 3HAY|C PF04137.10_ERO1_seed 39 665 !Q:12,12|22,41|44,131|136,148|150,156|161,164|176,178|182,196|198,198|207,214|218,218|230,231|233,336|338,339|362,369|371,376|380,380|382,388|390,390|393,408|411,428|437,437|444,450|478,480|484,485|487,492|494,497|499,508|515,521|535,538|540,540|543,545|547,547|549,553|555,555|559,560|578,578|586,586|611,611|618,620|624,625|628,642 Q:0,11|13,21|42,43|132,135|149,149|157,160|165,175|179,181|197,197|199,206|215,217|219,229|232,232|337,337|340,361|370,370|377,379|381,381|389,389|391,392|409,410|429,436|438,443|451,477|481,483|486,486|493,493|498,498|509,514|522,534|539,539|541,542|546,546|548,548|554,554|556,558|561,577|579,585|587,610|612,617|621,623|626,627|643,664 HTTHHHHHHHHH-SHHHHEEEE???-???-------------SS????--???-??--??---------------------??????????-?????--------???????----????---?????????HHHH-------------H???????HHHH----HHHHHHHHHHH---HTT-???-???????--?S?EEEEGGGS????????HHH-HHHHHHHHHTT??B--------------------??--????-??????????-------------------------------------------??????????????--?----?B??HHHHHHHHHHHHHHHHHHHHTE--------E------EEE?S-------S?EE----------------EE??----------------HHHHHHHH?HHHHTT-------HHHHHHHHHHHHHHHHHHHHHHTHHHH---HST--T?-????S---?S----------SHHHHH-------HHHHHHHHHHHHH----S?EE---E?T-----T?TTS??THHHHHHHHHHHHHHHH-HHHHHTT?SSHHHHHHHHHHHHHHHHHHHHHT?HHHHHT?-?SSS??SS--------??---??HHHHHHHHHHHHHHHHHHHHHH 3AHQ|A PF04139.8_Rad9_seed 16 400 !Q:11,11|29,29|33,33|41,41|49,55|57,59|63,66|79,102|117,122|125,125|128,166|177,177|185,185|188,197|201,201|220,220|223,224|229,239|242,242|246,248|255,270|272,275|282,282|284,284|287,287|292,293|296,313|324,350|361,361|368,368|373,373|378,381|384,387|397,399 Q:0,10|12,28|30,32|34,40|42,48|56,56|60,62|67,78|103,116|123,124|126,127|167,176|178,184|186,187|198,200|202,219|221,222|225,228|240,241|243,245|249,254|271,271|276,281|283,283|285,286|288,291|294,295|314,323|351,360|362,367|369,372|374,377|382,383|388,396 HHHHHHHHHTT?SEEEEEEETTEEEEEEE?TTS?EEEEEEE?GGGSSEE-------E???SSS????EEEEHHHHHHHH?----------------------?HHHHHHHEEEEEEE?----?TT?SE---------------------------------------EEEEEEEGGG?EEEEEEE?EE????-?????GGG?SEEEEEEHHHHHHHHTTS?TT??EEEE-----------EE?GGG?--EEEEEE???????---------S????EEEEEE?G-GG?SEEE??TT-----------------?EEEEEHHHHH---------------------------HHHHHHHHTT?EEEEEE?STTS?EEEE----EE--?-SSEEEEEEE??? 1W60|A PF04140.9_ICMT_seed 12 99 !Q:4,6|24,25|28,29|31,32|36,40|55,55|69,69|86,86 Q:0,3|7,23|26,27|30,30|33,35|41,54|56,68|70,85|87,98 HHHH---HHHHHHHHHHHHHHGGG??SS??E--ETT?????SSTTTTBSSHHHHH-HHHHHHHHHHHHT?HHHHHHHHHHHHHHHH-HHHHHHHHHHHH 4A2N|B PF04146.10_YTH_seed 59 334 !Q:0,1|11,11|22,22|26,27|32,39|51,61|66,66|76,76|82,82|84,85|89,263|265,265|267,270|272,272|280,280|282,282|291,298|303,303|311,313|319,319|333,333 Q:2,10|12,21|23,25|28,31|40,50|62,65|67,75|77,81|83,83|86,88|264,264|266,266|271,271|273,279|281,281|283,290|299,302|304,310|314,318|320,332 ??EEEEEEESS-SHHHHHHHHT?EEE??TTSH--------HHHHHHHHHSS----------?EEEE-EEESSSSEE?EEEEE?S?-SSS?----------------------------------------------------------------------------------------------------?????---------------------------------------------------------------------S?S????E-EEEEEEE?S?EEHHHHTS?-------EETT-STTEETT???TTEEE?TTHHHHHHGGGGT? 2YU6|A PF04151.10_PPC_seed 151 175 !Q:0,1|7,8|10,11|13,33|39,66|69,70|73,74|76,76|80,92|95,102|105,121|124,144|147,162|166,166|168,168 Q:2,6|9,9|12,12|34,38|67,68|71,72|75,75|77,79|93,94|103,104|122,123|145,146|163,165|167,167|169,174 ??EEEEE??S--S???-??--??---?-------BSSSS---------------------------?EE--EE--B?BSS--?---?-----?SS?------?SB??-------------??SS---------------------SS????--???------?TTS?E-EEEEEE 4HPK|A PF04152.9_Mre11_DNA_bind_seed 56 249 !Q:7,7|11,12|23,23|26,30|32,32|36,37|43,43|49,60|62,62|75,86|92,93|95,95|99,106|114,114|118,139|147,147|152,152|154,154|157,163|169,248 Q:0,6|8,10|13,22|24,25|31,31|33,35|38,42|44,48|61,61|63,74|87,91|94,94|96,98|107,113|115,117|140,146|148,151|153,153|155,156|164,168 EEEEEEE?SSS??EEEEEEEGGG?TT-----S?SSS??HHHHH-HHHHH------------H-HHHHHHHHHHHH------------HHHHT??S?TTS????--??EEEEEEE?TTT-----------------?????HHHHHHT-TTTT?S?TT------?SEEEE---?-???-------------------------------????-----------??------------------------ 3T1I|A PF04153.13_NOT2_3_5_seed 66 207 !Q:7,9|12,14|17,17|19,21|25,35|37,41|45,45|48,52|54,68|70,70|78,79|82,82|85,89|101,102|118,118|121,121|125,125|131,132|135,140|144,152|156,158|161,163|174,184|190,190|193,196|205,206 Q:0,6|10,11|15,16|18,18|22,24|36,36|42,44|46,47|53,53|69,69|71,77|80,81|83,84|90,100|103,117|119,120|122,124|126,130|133,134|141,143|153,155|159,160|164,173|185,189|191,192|197,204 HHHHHTT???GG---GT-S???SSS--------???B??-??TTS?SS?---?T---------------T?SSHHHHH--SS?HH-----HHHHHHHHSTT--SHHHHHHHHHHHHTT?EE?SSS?SEEEE--SS??----SEE?--------SSE---EE---EEEEEEETTT-----------TEEEE-EE----EEEEEGGG?? 4C0D|B PF04157.11_EAP30_seed 67 439 !Q:0,30|57,57|63,78|89,90|92,96|99,99|102,111|119,122|139,146|154,176|178,182|196,200|203,203|206,247|259,259|263,263|266,267|274,288|295,295|297,302|313,388|404,413|423,424|426,426|433,433|435,436 Q:31,56|58,62|79,88|91,91|97,98|100,101|112,118|123,138|147,153|177,177|183,195|201,202|204,205|248,258|260,262|264,265|268,273|289,294|296,296|303,312|389,403|414,422|425,425|427,432|434,434|437,438 ??????????????????????????--???HHHHHHHHHHHHHHHHHHHHTTHHHH?HHHHH----------------HHHHHHHHHT??T-----TS?TT----------SHHHHHH--??HHHHHHHHHHHHHHHH--------HHHHHHT-----------------------T-----EEEHHHHHHHHHH-----HT?SS?-------------------------------------????HHHHHHHHHHH-GGG?SS-?EEEEET---------------TEEEEE?S?-????HHHHHHHHHH----------------------------------------------------------------------------TTTSEEEHHHHHHHH?-------??HHHHHHHHH--H-HHHTTS?E--EE 1U5T|A PF04166.7_PdxA_seed 16 409 !Q:1,2|6,10|13,13|20,20|25,26|35,47|52,53|57,63|68,68|73,76|79,87|89,96|98,98|101,102|125,125|131,134|142,145|147,151|159,164|168,174|176,182|187,187|191,196|198,198|205,205|207,208|216,217|237,238|241,241|247,247|259,259|268,288|296,297|301,301|305,309|311,315|318,318|327,334|339,342|361,361|363,363|366,366|380,380|383,385|393,397 Q:0,0|3,5|11,12|14,19|21,24|27,34|48,51|54,56|64,67|69,72|77,78|88,88|97,97|99,100|103,124|126,130|135,141|146,146|152,158|165,167|175,175|183,186|188,190|197,197|199,204|206,206|209,215|218,236|239,240|242,246|248,258|260,267|289,295|298,300|302,304|310,310|316,317|319,326|335,338|343,360|362,362|364,365|367,379|381,382|386,392|398,408 H--TTS---??SS-EEEEEE?HHHH--HHHHHHTT??-?---------EEEE??TTS-??????TTEE-EEEE???-SS------?-?B--------T-TB??TTHHHHHHHHHHHHHHHHHTTS?SEEEE????HHHHHHT----T?????HHHHHHH------HTT------?S-----??EEEE-ESS------S?EEEESS?S??GGGHHHH??HHHHHHHHHHHHHHHHHTT??SS?EEEEE?SSGGGGTTTTT?SHHHHTHH---------------------HHHHHHH--HTT?EEE-----E-----EE?HHHHSSHH--------HHTT?---SEEEESSHHHHHHHHHTT?S-SS?EEEEESSSSEEEE?SS???GGGTTSS-????HHHHHHHHHHH 1R8K|A PF04167.8_DUF402_seed 76 90 !Q:1,2|5,5|11,12|15,15|24,24|27,27|41,42|48,51|56,56|64,67|69,71|75,80|85,85 Q:0,0|3,4|6,10|13,14|16,23|25,26|28,40|43,47|52,55|57,63|68,68|72,74|81,84|86,89 E??SS?EEEEE?-TT?SEEEEEEE-ET-TTEEEEEEEEEES??EEETT----EEEE?EEEEEEE----E--?TTS-----?EEEE?HHHH 2P12|A PF04170.7_NlpE_seed 17 90 !Q:5,6|19,19|33,33|37,38|49,49|55,55|62,64|79,79|83,83|85,85 Q:0,4|7,18|20,32|34,36|39,48|50,54|56,61|65,78|80,82|84,84|86,89 EEEEE??SSSSEEEEEEEE?TTSEEEEEEEEET?SSS??EEEEEEEEEE?SSEEE-EEETTS?--EEEEEEETTEEEEE?TTS?B?EEEE 2Z4H|A PF04174.8_CP_ATPgrasp_1_seed 28 368 !Q:0,0|4,4|33,33|39,42|46,46|52,53|56,57|63,65|69,69|71,71|81,81|85,85|93,93|96,98|113,113|121,126|128,130|146,146|149,149|151,151|153,155|160,162|170,176|187,187|191,191|198,198|201,201|205,206|208,208|210,211|213,213|216,216|221,221|223,223|225,225|229,229|234,234|237,237|241,241|253,253|257,257|259,259|275,275|283,286|288,288|290,291|296,300|307,307|325,337|344,345|347,347 Q:1,3|5,32|34,38|43,45|47,51|54,55|58,62|66,68|70,70|72,80|82,84|86,92|94,95|99,112|114,120|127,127|131,145|147,148|150,150|152,152|156,159|163,169|177,186|188,190|192,197|199,200|202,204|207,207|209,209|212,212|214,215|217,220|222,222|224,224|226,228|230,233|235,236|238,240|242,252|254,256|258,258|260,274|276,282|287,287|289,289|292,295|301,306|308,324|338,343|346,346|348,367 ?EEE?HHHHHHHHHHHHHHHHHHHHHHHHHTTT?HHHHT----TSS?GGGGG-?TT??GGGTT???GGG?S?SEEEEEEEE?SSS?EEEEEEE?SS???HHHHHHHHHHHHHH?HHHHHHS-----?B???TTHHHHHHHHHHHTS?TT?S-S??-EEEE???SSSTTHH-------HHHHHHHHHT?EEE?GGGEEE?SS?EEE??T-T??E-EE?EEEE?S?G-GGS?TTTS?TT?SSS?TTHHHHHHTTS?EEE-S?TTTHHHHSTTTGGGH-HHHHHHH----H?S??SSEE--???EETTSH-HHHHHHHHSGGGEEEEE?????-----???EEEGGG??H-HHHHHHHHHHHHSGGGEEEE 3N6X|A PF04175.7_DUF406_seed 51 108 !Q:0,0|3,13|16,16|20,26|28,29|31,33|44,44|66,70|73,73|78,81|84,85|93,93 Q:1,2|14,15|17,19|27,27|30,30|34,43|45,65|71,72|74,77|82,83|86,92|94,107 ?SS?????------SS?SSS?--????S??S???STTEEEEEEE?SSHHHHHHHHHHHHHHHHHHS-----TT?EEEE????TT??EEEEEEE?SSHHHHHHHHHHHH 2JZ5|A PF04177.7_TAP42_seed 39 501 !Q:0,0|19,23|26,26|29,29|38,40|58,65|70,70|90,102|104,104|135,138|148,148|153,153|155,156|162,164|169,170|202,250|281,281|285,370|372,379|381,500 Q:1,18|24,25|27,28|30,37|41,57|66,69|71,89|103,103|105,134|139,147|149,152|154,154|157,161|165,168|171,201|251,280|282,284|371,371|380,380 ?HHHHHHHHHHHHHHHTSS----?SS?TT?HHHHHHHH---HHHHHHHHHHHHHHTTS????????GGGS?GGGGGGGGHHHHHHHHHTT?????--------S?HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-???HHHHHHHHT?SSTT-S??HHHHS???SSTT-?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH???-------------------------?????????------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHH--------------------------------------------------------------------------------------T--------T----------------------------------------------------------------------------------------------------------?------------- 3QC1|A PF04181.8_RPAP2_Rtr1_seed 45 143 !Q:4,5|17,19|23,23|25,26|30,30|32,33|35,36|38,118|123,123|132,132|141,142 Q:0,3|6,16|20,22|24,24|27,29|31,31|34,34|37,37|119,122|124,131|133,140 HGGG??HHHHHHHHHHH---HTT-T??SST-T??S??S??------?????????--------------???????????---------------------------------------GGGT?SSHHHHHH-HHHHHTTS?? 4FC8|A PF04183.7_IucA_IucC_seed 168 380 !Q:3,3|8,11|14,14|16,17|19,19|23,23|26,29|32,33|41,41|46,47|49,51|68,68|71,88|93,103|109,109|116,117|123,145|150,151|157,157|162,162|172,174|187,193|199,200|205,205|209,209|217,221|225,228|232,236|241,244|250,256|277,278|282,286|290,292|295,296|304,305|312,313|315,333|336,336|346,347|352,353|355,355|358,365|370,371|377,377|379,379 Q:0,2|4,7|12,13|15,15|18,18|20,22|24,25|30,31|34,40|42,45|48,48|52,67|69,70|89,92|104,108|110,115|118,122|146,149|152,156|158,161|163,171|175,186|194,198|201,204|206,208|210,216|222,224|229,231|237,240|245,249|257,276|279,281|287,289|293,294|297,303|306,311|314,314|334,335|337,345|348,351|354,354|356,357|366,369|372,376|378,378 TTS?HHHH----HH-T??S?SSS?SS????BT??HHHHHHH?GGGT??E---EEEEEEEETTTEEEEE?TT----------------??HHHH-----------HHHHT?HHHHHH--HHHHH-----------------------HHTT??GGGEE-EEEE?HHHHHHTTT---TTTHHHHHTTSE-------EEEEE--EEEE-EEE?TTSSEEE-----ESS----STT---??EEEE????BSSSB--?????HHHHHHHHHHHHHHHHHHHT-?HHH-----HHH-??EE??EEEEEEE??HHHHHH??S-----------------??GG-GSSSEEEEE??GGGG--S?TT-------?EEEE--GGGGG?B? 2W03|A PF04185.9_Phosphoesterase_seed 20 566 !Q:0,1|9,9|11,12|22,26|30,59|62,70|72,74|81,81|83,86|90,91|94,95|99,106|119,121|128,130|145,146|154,154|169,169|174,174|185,185|187,206|210,210|213,214|222,243|246,246|248,249|254,254|265,265|269,269|274,282|284,289|299,300|308,308|310,310|320,322|326,326|330,330|335,336|340,340|349,350|353,361|363,363|390,392|399,407|412,416|420,421|442,442|454,455|458,467|472,504|508,513|515,516|524,525|527,527|533,544|560,565 Q:2,8|10,10|13,21|27,29|60,61|71,71|75,80|82,82|87,89|92,93|96,98|107,118|122,127|131,144|147,153|155,168|170,173|175,184|186,186|207,209|211,212|215,221|244,245|247,247|250,253|255,264|266,268|270,273|283,283|290,298|301,307|309,309|311,319|323,325|327,329|331,334|337,339|341,348|351,352|362,362|364,389|393,398|408,411|417,419|422,441|443,453|456,457|468,471|505,507|514,514|517,523|526,526|528,532|545,559 ??EEEEEEE?S??HHHHHTTTT?????TTS------------------------??????TT?-----???S???HHHHHS?S----SSS??EE??TTS????????HHHHHHHHGGGT???HHHHHS???HHHHHHHTTGGGEE??TTTSHHH-HHHHHHSEEESSEE?SSSS?HHHHHHHHHH-S???-----------------SEE?TT??TTTEETT----------------------EE?S??EESS?GGGSTTSTTS?TTS?EEEE?--------S??---?HHHHHHHHT??EEEEETT?S?SEEETTEEE???EEE?TTS?EEES??GGG?GGGGSGGG??TT??-----??S?GGGTTSBSTTTTEEEHHHHHHHHHTT???SEEEEE?-------?GGGS?---?TTT??HHHHHHHHHHHHHHHHTSTT-GGGEEEEEEES??TT??????????TTTT---------------------------------STT??????B??EEEESTT--B?TTEEE??---------?EETHHHHHHHHHHHT----?? 2D1G|A PF04187.8_DUF399_seed 84 351 !Q:1,2|13,13|21,21|24,24|26,27|41,41|49,53|55,57|80,87|91,92|102,103|105,105|108,111|127,128|134,135|145,157|159,164|168,169|171,175|184,187|192,196|201,264|274,290|297,298|312,312|314,323|336,339 Q:0,0|3,12|14,20|22,23|25,25|28,40|42,48|54,54|58,79|88,90|93,101|104,104|106,107|112,126|129,133|136,144|158,158|165,167|170,170|176,183|188,191|197,200|265,273|291,296|299,311|313,313|324,335|340,350 E??HHHHHHHHTT?SEEEEEE?TT?H--HHHHHHHHHHHHH-HHHHHHT-----T?-?EEEEEEEEEGGGHHHHHHHHHT--------GGG??TTTHHHHTT??T-TS--?-GGGTHHHHHHHHTSS??EEEEE??HHHHHHHHT-------------T??????SSS--S-?---HHHHHHHH----HHHH-----HHHT??--------------------------------------------------------------TTTTHHHHH-----------------HHHHHH--HHHHHHHHHHHHH?S----------SEEEEEEEHHHH---?TTTSHHHHHHH 2G5G|X PF04190.8_DUF410_seed 5 292 !Q:4,4|24,24|42,51|54,56|71,72|75,75|78,83|96,99|105,105|108,109|125,125|137,137|157,159|199,201|218,218|235,235|246,246|249,251|269,291 Q:0,3|5,23|25,41|52,53|57,70|73,74|76,77|84,95|100,104|106,107|110,124|126,136|138,156|160,198|202,217|219,234|236,245|247,248|252,268 HHTT?HHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHH----------TT???SHHHHHHHHHHHTT??TT?TT------HHHHHHHHHHHH----HHTSS?TT??HHHHHHHHHHHHHTT?HHHHHHHHHTS?HHHHHHHHHHHHHHHHHTT???HHHHHHHHHHHHHHHHHTTBHHHHHHHHHHHHHHHHHHH???EEEEEETTEEEEEESS?HHHHHHHHHHHHHHHT?HHHHHHHHHH?HH---HHHHTHHHHHHHHHHHH?????????---??????????? 3LPZ|A PF04191.8_PEMT_seed 105 118 !Q:4,4|27,28|31,36|41,53|79,79|82,82|86,86 Q:0,3|5,26|29,30|37,40|54,78|80,81|83,85|87,117 HHHH-HHHHHHHHHHHHHHHHHHHGGG??SS??----EETT--?------????SSTTTTBSSHHHHHHHHHHHHHHHH-HT?HHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHTHHH 4A2N|B PF04197.7_Birna_RdRp_seed 5 990 !Q:0,30|33,41|44,44|47,49|61,62|64,68|72,73|83,84|90,102|105,106|117,124|127,127|131,132|135,138|155,156|161,166|183,185|204,206|208,211|217,219|232,245|247,247|249,249|256,257|260,266|269,269|271,274|295,295|316,316|322,346|368,369|380,382|387,388|406,408|416,417|419,419|422,423|437,439|443,445|462,466|480,481|499,499|507,507|525,525|532,532|536,537|540,542|566,587|601,603|624,626|631,631|636,639|642,645|669,669|680,687|690,690|694,696|735,738|744,745|753,754|758,759|761,761|771,776|778,779|790,798|801,804|806,809|821,824|827,827|840,840|842,846|851,853|866,874|891,891|893,894|897,898|908,989 Q:31,32|42,43|45,46|50,60|63,63|69,71|74,82|85,89|103,104|107,116|125,126|128,130|133,134|139,154|157,160|167,182|186,203|207,207|212,216|220,231|246,246|248,248|250,255|258,259|267,268|270,270|275,294|296,315|317,321|347,367|370,379|383,386|389,405|409,415|418,418|420,421|424,436|440,442|446,461|467,479|482,498|500,506|508,524|526,531|533,535|538,539|543,565|588,600|604,623|627,630|632,635|640,641|646,668|670,679|688,689|691,693|697,734|739,743|746,752|755,757|760,760|762,770|777,777|780,789|799,800|805,805|810,820|825,826|828,839|841,841|847,850|854,865|875,890|892,892|895,896|899,907 ???????????????????????????????SS?????????TT?SH---HHHHHHHHHTT??B?????EEE--EEEEEHHHH-?STTTT?????---?????SE--EEEEEEEEEE????????SS?SSS??SS-???HHHHHHHHHHHHHSSS??HHHH------HHHHHHHHHHHHEEEE???HHHHHHHHHHHHHHHHTS---S????GGGGT?-?HHHHHHHHHHHS??????????????B?S?GGGGEE??SS???????EE?S????TTSEEETTEEEEEGGGGHHH-HHHHHHHHHHHHHHHHHSTT?GGGTT-------------------------HHHHHHHHHHTGGGGEEEEEE??EEEEGGGTTT???EEEE??HHHHHHHHHHHHHHHTT???STTTSTT??B?TT??STTTHHHHHHHHH---HSS-??SEEEEETTEEEEEETT-----EEEEEEESSSGGG??HHHHHHHHHHHHHHTSE-ETTEESB?HHHHHHHHHTHHHHHBS?EEESSS?EEE??SB???SSTTHHHHHHHHHHHHHHHHHTT??-------------------?TTSHHHHTHHHHH???EEEEEEEESHHHHHHHHHHS?-?SBTT-BBSS?--?SS????EEEEETTEEEEEETTTTEEEEEE?HHHHHHHHHS????????SS?SHH---HHHHHHHHHHHHHHHHTGGGSHHHHHHHHHHHHHHHHH----HHHHT??HHHHGGG--HHH--H-STTGGGGTT???--?S??SHHHHHHHHS?????????SS????S---?HHHHHHHHHTS????TT?HHHHHHHHHHHB?S-----TTHH---HHHHHHHHHHTS????????-SHHHHHHHHHHHHHTT?B??TT??HHHHHHHHT????------????????????????????????????????????????-------------------------------- 2R72|A PF04198.8_Sugar-bind_seed 31 283 !Q:2,3|18,18|25,40|43,43|58,58|60,62|65,67|72,73|85,88|91,94|101,101|103,103|108,109|113,113|116,116|127,127|129,129|132,135|140,140|165,165|171,172|174,174|177,180|184,184|190,190|198,198|211,211|218,218|220,223|230,230|232,233|247,249|264,264|266,266|268,268|282,282 Q:0,1|4,17|19,24|41,42|44,57|59,59|63,64|68,71|74,84|89,90|95,100|102,102|104,107|110,112|114,115|117,126|128,128|130,131|136,139|141,164|166,170|173,173|175,176|181,183|185,189|191,197|199,210|212,217|219,219|224,229|231,231|234,246|250,263|265,265|267,267|269,281 SS??HHHHHHHHHHHHHT?SEEEEE--????-----???-?HH-HHHHHHHHHHHHHH-H??-TT?--EEEE??SHHHHHHHTTS???-SS????EEEESB?B?TTSS-?GGG?HH-HHHHHHHHHT-T?EE????SBSB?SSHHHHHHHHHSHHHHHHHHHHTT?SEEEE??B?TT?--?SSS?HHHHH?THHHHHH-HHTTEEEEETTE-EEETTS?B??-?SSGGGB?B??HHHHHTSSEEEEE???GGGHHHHHHHHHTT-S?S-EEEEEHHHHHHHH? 3BXH|A PF04199.8_Cyclase_seed 76 337 !Q:3,6|8,22|25,36|39,43|45,45|50,50|54,70|77,86|92,92|95,95|97,97|107,108|111,131|133,160|163,165|169,169|176,176|179,193|197,197|205,216|219,219|225,267|270,272|275,276|278,279|282,292|295,295|304,304|308,311|320,320|322,334|336,336 Q:0,2|7,7|23,24|37,38|44,44|46,49|51,53|71,76|87,91|93,94|96,96|98,106|109,110|132,132|161,162|166,168|170,175|177,178|194,196|198,204|217,218|220,224|268,269|273,274|277,277|280,281|293,294|296,303|305,307|312,319|321,321|335,335 EEE????B?--------------TT-?--------??GG-----G?GGGS?EEE-----------------EEEETT----------EEEEE-EE-E-ETTSSSEEE??GG---------------------G????----------?------???????TT---TEE-EEEEEE?TT-------------??SEE?HHHHTTS---------???TT?EEEEE?------------------------------------------GG---GG??S??TT---------??EE?HHHHHHHH-HHT?---SEEEESSS?S-----------??S? 3KRV|A PF04200.7_Lipoprotein_17_seed 272 197 !Q:3,4|6,14|23,37|44,46|48,48|52,53|55,55|65,65|68,72|76,76|78,82|91,99|104,109|111,112|118,131|138,138|140,140|144,145|147,153|158,160|164,166|168,180|184,186|190,190|192,193|195,197 Q:0,2|5,5|15,22|38,43|47,47|49,51|54,54|56,64|66,67|73,75|77,77|83,90|100,103|110,110|113,117|132,137|139,139|141,143|146,146|154,157|161,163|167,167|181,183|187,189|191,191|194,194 HHT--T?-------?BTTTEEEE---------------ESSSTT-??G-GGS?-H-HHHHTTGGG?EE-----EEE?S----?TTTEEEEE---------EEEE?-----T--TSSHH--------------HHHHHT?E-EEE--E-------EEEE---TTT?-?E-------------EEE---EEE-E??S??- 3JVC|A PF04203.8_Sortase_seed 138 292 !Q:2,2|7,9|12,14|16,16|19,20|22,23|26,26|32,39|41,41|45,45|47,47|50,51|55,55|58,59|63,82|92,92|94,94|96,104|112,112|116,116|124,124|126,127|134,148|151,151|154,155|159,165|171,181|183,203|211,212|219,222|226,226|229,236|239,242|250,283 Q:0,1|3,6|10,11|15,15|17,18|21,21|24,25|27,31|40,40|42,44|46,46|48,49|52,54|56,57|60,62|83,91|93,93|95,95|105,111|113,115|117,123|125,125|128,133|149,150|152,153|156,158|166,170|182,182|204,210|213,218|223,225|227,228|237,238|243,249|284,291 EE?TTSS--?EE---E-EE??S--SS-STTSS--------B?TTS?B?TT??EEE?TT??TTS?-----------------?-SEEEEEEEB?T-T---------STBTGGG-GGG-GSHHHHH-H??EEEEEE---------------SS?EE--EEE-------EEEEE-----------E-?------?--??????????SSHHHHH--HHHHHH----HHT?SS???-????TT--??EEEEEEE?------??-------???-----------????EEEEEEEE 3G66|A PF04204.11_HTS_seed 77 345 !Q:0,0|3,4|7,7|18,20|22,33|40,42|46,47|62,63|66,66|73,74|76,80|83,83|91,91|93,93|98,99|102,103|110,112|114,114|118,118|158,161|176,177|181,182|184,184|189,190|203,204|209,211|214,217|233,233|237,237|243,245|247,247|250,251|267,278|282,308|313,313|317,321|342,345 Q:1,2|5,6|8,17|21,21|34,39|43,45|48,61|64,65|67,72|75,75|81,82|84,90|92,92|94,97|100,101|104,109|113,113|115,117|119,157|162,175|178,180|183,183|185,188|191,202|205,208|212,213|218,232|234,236|238,242|246,246|248,249|252,266|279,281|309,312|314,316|322,341 ?EE??TT?HHHHHHHTTT???B????????????EEEEEE???SSH--HHHHHHHHHHHHSS--SS?EEEEEE??S?????SS?HHHHHHH?B?GGGT--TT??EEEEEE???S?TTS?GGGSTTHHHHHHHHHHHHHHEEEEEEETHHHHHHHHHHH????EEEEEEEEEEEEEE--ESS??G-GGTT??SEEEEEEEEEEE??HHHH---TT????EEEEEETTTEEEEEE?SSS-SEEEE--?S?TT??TTHHHHHHHHHHHTT?-?-----????BTT---------------------------SGGG?TTS?????SHHHHHHHHHHHHHHTTTTT???- 2VDJ|A PF04205.9_FMN_bind_seed 182 232 !Q:0,0|4,9|12,12|17,23|26,31|41,43|48,55|57,78|80,99|104,107|112,129|131,132|137,142|148,148|152,168|174,177|182,194|197,199|203,204|206,206|209,210|213,213 Q:1,3|10,11|13,16|24,25|32,40|44,47|56,56|79,79|100,103|108,111|130,130|133,136|143,147|149,151|169,173|178,181|195,196|200,202|205,205|207,208|211,212|214,231 ?SSS------EE-EEEE-------EE-----?TTSSBEEEE---EEEE--------S----------------------S-----------?-------?TTTG----GGGG------------------S--HHHH------GGGTT?BSE-----------------ETTEE???-EEES-------------TT???TTS-?E-EE??TT?HHHHHHHHHHHHHHHHHH 2KZX|A PF04209.8_HgmA_seed 14 486 !Q:0,0|4,4|7,8|13,13|19,19|21,21|24,24|26,27|30,30|34,34|42,42|44,44|47,48|52,53|62,62|65,65|67,69|72,78|81,84|89,94|96,96|100,100|102,106|110,113|128,129|143,143|145,147|153,153|167,167|180,180|188,188|191,192|197,197|199,199|202,203|214,216|218,226|233,233|236,236|244,256|259,259|281,281|283,284|292,294|296,298|305,305|307,310|315,317|328,328|333,333|341,342|344,344|349,350|352,352|355,356|358,362|364,370|375,383|387,388|390,403|406,406|411,411|414,415|417,419|430,436|439,440|445,446|455,456|459,459|466,485 Q:1,3|5,6|9,12|14,18|20,20|22,23|25,25|28,29|31,33|35,41|43,43|45,46|49,51|54,61|63,64|66,66|70,71|79,80|85,88|95,95|97,99|101,101|107,109|114,127|130,142|144,144|148,152|154,166|168,179|181,187|189,190|193,196|198,198|200,201|204,213|217,217|227,232|234,235|237,243|257,258|260,280|282,282|285,291|295,295|299,304|306,306|311,314|318,327|329,332|334,340|343,343|345,348|351,351|353,354|357,357|363,363|371,374|384,386|389,389|404,405|407,410|412,413|416,416|420,429|437,438|441,444|447,454|457,458|460,465 ?EEE?TT??EEEE?TTSTT?S?SS?S??SS?GGG?EEEEEES-S?TT??GGG??EEEEEESS?TT?S???EE??----?TB????TTSS??--??S?EEE?S?????TTT????TTTTEEEEEEEEET--TTTEEEEEEEEEE?S???SEEEE-ESSEEEEEEEEES?EEEEETTEEEEE?TTEEEEE?TT??EEEE?S-SS--EEEEEEEEES???B??-----??GGGTTS?BS?GGGEEEE?------??????EE-EEEEEEEEEETTEEEEEEEEE?S??EEEEEES???E---EEEGGG?B????SSSS???GGGGEEEEEE?SSTT?EEEEEEE--E?SEEE??T-TS??S?--??B??-----SSEE---------EEE--E???????????-??TT?EEEE?TT??B???HHHHHHHHHS---????EE--ESTT??EEEEEESS??EE?HHHHHH???????????-???????? 1EY2|A PF04212.13_MIT_seed 82 89 !Q:17,19|22,30|33,33|53,60|68,69|88,88 Q:0,16|20,21|31,32|34,52|61,67|70,87 HHHHHHHHHHHHHHHHH---TT-------??SS-HHHHHHHHHHHHHHHHHHS-----??-TGGGGHH--HHHHHHHHHHHHHHHTTT? 1WR0|A PF04216.7_FdhE_seed 49 375 !Q:0,23|26,28|36,40|51,52|54,54|69,69|74,76|80,88|95,97|103,104|107,107|115,115|120,121|130,136|138,138|145,146|154,158|172,181|183,183|188,188|190,191|212,215|218,218|220,223|226,229|232,232|236,238|246,259|261,261|270,271|275,276|280,280|284,286|288,289|293,311|315,315|334,334|338,338|341,342|345,345|359,359|364,364|367,370|373,374 Q:24,25|29,35|41,50|53,53|55,68|70,73|77,79|89,94|98,102|105,106|108,114|116,119|122,129|137,137|139,144|147,153|159,171|182,182|184,187|189,189|192,211|216,217|219,219|224,225|230,231|233,235|239,245|260,260|262,269|272,274|277,279|281,283|287,287|290,292|312,314|316,333|335,337|339,340|343,344|346,358|360,363|365,366|371,372 ??--????-------?????????EE???TTHHHHH-----HHHHHHHHTT-?T-THHHHHHHHHHHHH-HHHH---HTS?-???????HHHHHH---HHHTT??TT?HHHHHHH?TTHH--HHHHHHHT????---S-SHHHHH--HHHHHHH---??HHHHHHHHHHHHT----------T?GGGS?G--GGHHHHHHHHHHHHHHHHHT--??TT?S??-?TT?---SS?TTT???EEEEEEE??????-------?E-EEEEETTT??EEE??TTS?SSS???S??EEE???-----------?????STT?SEEEEEETTTTEEEEEEE-TTT?TT??HH-HHHHTTHHHHHHH-HHTT?EE????TT?? 2FIY|A PF04218.8_CENP-B_N_seed 6 55 !Q:0,1|4,7|21,21|25,25|35,36 Q:2,3|8,20|22,24|26,34|37,54 ??SS????HHHHHHHHHHHHH?TTS?HHHHHHHHT??HHHHHHHHHTHHHHHHHH 1HLV|A PF04221.7_RelB_seed 6 89 !Q:0,1|7,8|24,25|43,43|46,47|67,88 Q:2,6|9,23|26,42|44,45|48,66 ??EEEEE??HHHHHHHHHHHHHHT??HHHHHHHHHHHHHHHSS?SS??HHHHHHHHHHHHHHHHHHH??----------?????????? 4FXE|A PF04222.7_DUF416_seed 48 223 !Q:0,1|10,10|38,38|40,41|58,58|60,60|62,66|75,75|79,81|85,87|91,93|110,117|123,123|125,126|146,148|152,157|161,163|189,190|196,198|213,216|220,222 Q:2,9|11,37|39,39|42,57|59,59|61,61|67,74|76,78|82,84|88,90|94,109|118,122|124,124|127,145|149,151|158,160|164,188|191,195|199,212|217,219 ??HHHHHHHS?HHHHHHHHHHHHHHHHHHHHHHHHHHT?S?-HHHHHHHHHHHHHHHH?T-T?-???HHHHHHHH-HHT???GGG-??STT---HHHHHHHHHHHHHHHH--------HHHHT?H--HHHHTHHHHHHHHHHHHHH---HHH?????-HHH---HHHHHHTSHHHHHHHHHHHHHHHHH--HTSSS?-?HHHHHHHHHHHHHH-???TTS??? 2Q9R|A PF04223.7_CitF_seed 5 468 !Q:0,2|6,6|16,17|20,20|25,26|33,33|47,48|56,58|62,62|82,82|94,95|98,98|102,103|117,118|129,129|133,133|142,143|145,146|156,156|167,168|171,171|174,174|177,177|181,181|187,187|189,189|192,192|199,206|226,226|230,230|234,235|255,257|262,262|266,266|304,305|311,311|316,317|322,322|328,329|333,333|336,337|340,340|343,343|346,347|349,350|352,352|369,370|380,380|383,383|386,386|389,389|393,394|398,398|401,401|405,405|408,408|418,418|420,420|422,422|425,425|438,438|440,444|455,455 Q:3,5|7,15|18,19|21,24|27,32|34,46|49,55|59,61|63,81|83,93|96,97|99,101|104,116|119,128|130,132|134,141|144,144|147,155|157,166|169,170|172,173|175,176|178,180|182,186|188,188|190,191|193,198|207,225|227,229|231,233|236,254|258,261|263,265|267,303|306,310|312,315|318,321|323,327|330,332|334,335|338,339|341,342|344,345|348,348|351,351|353,368|371,379|381,382|384,385|387,388|390,392|395,397|399,400|402,404|406,407|409,417|419,419|421,421|423,424|426,437|439,439|445,454|456,467 ???EES?HHHHHHHTT??TT?EEEE??TTGGGB?HHHHHHHHHHHTT??SEEEEES???GGG-TTHHHHHHTTSEEEEEESB?HHHHHHHHHTT??SS?EEE??HHHHHHHHHHTSS??SEEEEEESEE?TTS?EESSSSSS??S??HHHHHHHHH?SEEEEEESSB??SS?SS?SB?GGG?SEEEE?S?SB?THHHHS????????HHHHHHHHHHHHHHHTSTT?STT?EEE??SSHHHHHHHHHHHHHHHHS???EEEE?SEE?HHHHHHHHTTSEEEEEESEESSHHHHHHHHHTTTEEE??HHHHH?SSSS??GGGG?SEEEE??SEE?TT??EE?SB?TT??B??B?TTHHHHHHHSSEEEEE??SEETTEESB?SS?SS?SB?GGG??EEE?SS?EEE?TT?HHHHHHTTT?S-S?EE?HHHHHHHHHHHH?S?????EEEEEEEEEE?TTSSEEEEEEEE 2NVV|A PF04225.7_OapA_seed 12 86 !Q:0,1|6,7|10,11|21,22|37,38|42,43|46,46|53,53|57,57|69,72|76,76|80,80|84,85 Q:2,5|8,9|12,20|23,36|39,41|44,45|47,52|54,56|58,68|73,75|77,79|81,83 ??EEEE??TT??HHHHHHHTT??HHHHHHHHHHGGGT??GGG??TT?EEEEEE?TTS?EEEEETTEEEE----EEE?TTS?EEE-- 2GU1|A PF04227.7_Indigoidine_A_seed 90 335 !Q:10,13|18,18|27,27|47,47|63,64|74,78|83,84|89,89|101,107|111,111|124,125|129,129|131,131|133,134|138,142|144,145|147,150|154,155|157,157|167,168|176,176|180,180|193,194|199,203|205,205|207,212|214,215|221,222|224,224|226,226|231,232|246,248|251,252|254,255|260,263|267,269|289,292 Q:0,9|14,17|19,26|28,46|48,62|65,73|79,82|85,88|90,100|108,110|112,123|126,128|130,130|132,132|135,137|143,143|146,146|151,153|156,156|158,166|169,175|177,179|181,192|195,198|204,204|206,206|213,213|216,220|223,223|225,225|227,230|233,245|249,250|253,253|256,259|264,266|270,288|293,334 HHHHHHHHTT-?-?EEEE?SHHHHTSS?TTTTHHHHHHHHHHHHHTT?EEEEEEEETTEEEES??HHHHHHHHH-----HGGG--SEEE?TTTHHHHHHTT??-----EEE?HHHHHHHHHHHT??EEE?S?B??BBT-----T--H----HHH??B?HHHHHHHHS??EEEESSB?TTB?HHHHHHHHHHTT??EEEE-----S?S------B??BTTBS??S?B?SEEE??HHHHHHHHHHHHH---TT??S-?EEEE????GGG???HHHHHHHHHHHHHHHHHTT?--?GGGHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHH 1VKM|A PF04229.9_GrpB_seed 107 239 !Q:0,5|8,10|12,12|30,33|39,45|56,61|64,65|67,67|69,69|78,78|84,85|88,88|97,97|100,101|103,103|110,123|130,150|154,157|166,167|169,169|185,186|188,188|204,206|209,209|212,215|220,223|225,226|234,235 Q:6,7|11,11|13,29|34,38|46,55|62,63|66,66|68,68|70,77|79,83|86,87|89,96|98,99|102,102|104,109|124,129|151,153|158,165|168,168|170,184|187,187|189,203|207,208|210,211|216,219|224,224|227,233|236,238 ??????BS-??T-HHHHHHHHHHHHHHHHH----GGGEE-------EEEEESGGGS------TT??B?S?EEEEEEES?SGGGG--GG-HHHHHHTT?EE-?T-TTTSTT--------------EEEEEE?--------------------SSS--??EEEEEEET--T?HHHHHHHHHHHHHHH--H?HHHHHHHHHHHHHHH---TT?SS---?HHHH????H--HHHHHHH--HHH 2NRK|A PF04231.8_Endonuclease_1_seed 55 357 !Q:0,1|7,7|12,30|34,35|37,63|65,67|69,69|73,74|94,95|98,98|103,110|119,125|127,127|141,146|148,160|169,169|178,179|197,197|200,202|204,220|222,222|224,224|226,230|235,236|241,247|254,255|258,258|275,294|299,313|324,326|339,339|343,345|349,352|356,356 Q:2,6|8,11|31,33|36,36|64,64|68,68|70,72|75,93|96,97|99,102|111,118|126,126|128,140|147,147|161,168|170,177|180,196|198,199|203,203|221,221|223,223|225,225|231,234|237,240|248,253|256,257|259,274|295,298|314,323|327,338|340,342|346,348|353,355 ??HHHHH-HHHH-------------------HHH--T---------------------------T??-B?TTT??EEEEETTTEEEEETTTTTB??SS?HHHH--------TSEEEEES-------S?HHHHHTTSHHHHT------T-------------HHHHHHHH?HHHHHHHH-?GGGEEEEEHHHHHHHTT?EE???S-----------------S?T-T?---?SBTS??EEET-------TTTEEE??HH-HHHHHHHHHHHHHHHS-?--------------????HHHH---------------HHHHHHHHHS???HHHHHHHHHHHH-HHS???HHH----HTT? 1OUP|A PF04232.7_SpoVS_seed 26 87 !Q:0,2|7,7|10,11|34,34 Q:3,6|8,9|12,33|35,86 ??-EEEE?TT??HHHHHHHHHHHHHHHSEEEEEE?SHHHHHHHHHHHHHHHHHHGGGTEEEEEEEEEEEEEETTEEEEEEEEEEEEE 2EK0|A PF04234.7_CopC_seed 162 125 !Q:0,2|9,9|12,12|15,15|17,18|20,20|28,31|33,37|40,40|46,46|50,51|55,55|58,59|62,62|64,64|70,75|88,91|93,96|106,108|111,113|121,121|124,124 Q:3,8|10,11|13,14|16,16|19,19|21,27|32,32|38,39|41,45|47,49|52,54|56,57|60,61|63,63|65,69|76,87|92,92|97,105|109,110|114,120|122,123 ???EEEEES?TT?EE-S??S?EEEEESS???-G-----GG?EEEEE-EEE?-TTS?TT??EE-E?EEEEE?-----SSTTEEEEEESS?-??S----EEEEEEEEE??-TT???EEEEEEE-EE? 1OT4|A PF04237.8_YjbR_seed 196 172 !Q:5,8|10,15|18,18|20,24|26,28|33,44|47,47|49,56|61,64|74,75|77,78|80,86|88,88|93,97|102,105|110,110|117,118|124,124|126,126|129,129|131,132|135,135|140,140|142,144|146,149|151,151|153,153|156,156 Q:0,4|9,9|16,17|19,19|25,25|29,32|45,46|48,48|57,60|65,73|76,76|79,79|87,87|89,92|98,101|106,109|111,116|119,123|125,125|127,128|130,130|133,134|136,139|141,141|145,145|150,150|152,152|154,155|157,171 HHHHS????B--???-SS?S-----S?--EEEE?-----------TT-T?------?EEEE----EEEEEGGGG--T??S-------S?EEEE-----EEEE--??TTTH-HHHTTS--TTEEE?S-SS?T--TT-EEEE-E---T----T-S-SS?HHHHHHHHHHHHHHT 2A1V|A PF04239.7_DUF421_seed 196 148 !Q:0,7|17,17|22,23|28,29|39,39|42,42|44,46|57,57|61,61|67,67|69,69|72,72|74,76|82,94|104,104|113,114|127,142 Q:8,16|18,21|24,27|30,38|40,41|43,43|47,56|58,60|62,66|68,68|70,71|73,73|77,81|95,103|105,112|115,126|143,147 ????????EEEEETTEE?HHHH--HHTT??HHHHHHHHH-HT-T?-?SGGGEEEEEE?TTS?EEEEE?G-GG-S???TTTTT??????----???EEEEETTEE?HHHHHHHS??HHHHHHHHHHTT??--------------SGGGE 3C6F|A PF04242.8_DUF424_seed 44 106 !Q:6,6|19,19|26,27|32,33|38,39|43,46|65,65|87,87|91,91|105,105 Q:0,5|7,18|20,25|28,31|34,37|40,42|47,64|66,86|88,90|92,104 EEETTE-EEEEEEEGGGTT?EEEETT--EEEE??TTTS??EEE---?HHHHHHHHHHHHHHHTTT?EEEEEEESHHHHHHHHHTTSS?GGG?EESSSSEEEEEEE? 2QYA|A PF04244.8_DPRP_seed 107 268 !Q:3,4|7,9|12,12|18,22|26,27|33,34|40,44|47,49|72,73|78,78|81,86|89,90|92,93|107,107|109,111|116,117|119,119|129,135|139,139|141,141|145,148|152,152|162,163|165,166|169,170|187,187|191,191|199,200|205,212|214,216|218,230|244,244|246,247|251,256|258,260|262,267 Q:0,2|5,6|10,11|13,17|23,25|28,32|35,39|45,46|50,71|74,77|79,80|87,88|91,91|94,106|108,108|112,115|118,118|120,128|136,138|140,140|142,144|149,151|153,161|164,164|167,168|171,186|188,190|192,198|201,204|213,213|217,217|231,243|245,245|248,250|257,257|261,261 EEE??TT???TT?HHHHT?---?TTT?-EEEEE??HHHHH-----SS???HHHHHHHHHHHHHHHHHHHHTT??EEEE?TT-?----TT??S--SHHHHHHHHHHHH-T???EEEE??S?HHHHHHHHH-------SSS?E-EEE????SSS?HHHHHHHHT--T-?SS??HHHHHHHHHHHHTTTE-ETT-EEGGGSS??GGGS??????-?T---T??????????---HHHHHHHHHHHHH?T--TSS------S???S---??? 3ZXS|A PF04248.7_DUF427_seed 99 116 !Q:4,4|7,7|14,15|21,23|27,28|33,33|38,38|40,40|42,45|50,50|52,52|66,66|70,70|72,72|75,76|81,82|93,95|98,99|105,105|109,110|112,112|115,115 Q:0,3|5,6|8,13|16,20|24,26|29,32|34,37|39,39|41,41|46,49|51,51|53,65|67,69|71,71|73,74|77,80|83,92|96,97|100,104|106,108|111,111|113,114 EEEE?SS?EEEEES??EEEEE---TTS??EEEB?GGGB?G-G----GEEE-E-EEEEEETTTEEEE-EEE-E-EE--TTEE--EEEEEEEESS-??TT-?GGGTT?BEE-?T-TT? 3DJM|A PF04253.10_TFR_dimer_seed 36 160 !Q:1,3|28,38|41,41|48,51|53,54|67,67|69,71|73,73|77,77|81,82|97,104|120,120|122,122|125,132|158,159 Q:0,0|4,27|39,40|42,47|52,52|55,66|68,68|72,72|74,76|78,80|83,96|105,119|121,121|123,124|133,157 T???HHHHHHHHHHHHHHHHHHHHHHSS?----------TT?HHHHHH----H--HHHHHHHHHTTB?T---T?BTT-BTT??BSSEEEETTEEEEE--------EESHHHHHHHTTGGG?S?HH--------HHHHHHHHHHHHHHHHHHHHHTTSS?? 2CIJ|A PF04255.9_DUF433_seed 140 63 !Q:2,6|13,14|20,21|31,31|35,36|44,45|49,51 Q:0,1|7,12|15,19|22,30|32,34|37,43|46,48|52,62 EE?---?TTSGGG??EETTS??BHHHHHHHH-HTT??HHHHHHH--STT-??HHHHHHHHHHH 2GA1|A PF04257.9_Exonuc_V_gamma_seed 84 1302 !Q:0,0|8,8|23,24|26,38|41,46|50,50|65,76|81,83|85,87|89,92|105,105|109,115|117,120|122,123|125,132|134,134|147,151|154,159|161,170|173,173|176,176|185,197|201,201|204,214|236,249|260,282|285,286|291,291|293,303|312,314|323,327|330,337|344,345|352,354|357,359|361,362|364,364|371,375|389,390|399,399|401,401|404,405|407,414|423,424|432,441|443,444|457,457|462,462|464,465|467,473|493,517|525,540|542,542|544,558|571,582|589,590|596,599|602,603|629,632|636,639|641,641|643,650|660,660|673,676|678,681|683,694|698,701|704,705|707,709|716,716|729,729|732,735|754,755|771,772|774,774|776,776|783,785|787,788|790,797|816,816|818,833|836,847|850,853|855,859|863,863|888,891|894,895|913,924|931,933|945,945|953,970|972,979|981,981|983,983|998,998|1001,1002|1010,1010|1014,1016|1019,1022|1030,1031|1038,1043|1045,1045|1047,1047|1052,1053|1055,1061|1064,1066|1092,1092|1094,1095|1099,1100|1102,1103|1105,1105|1121,1121|1124,1124|1126,1134|1137,1137|1150,1156|1158,1160|1171,1189|1194,1195|1197,1199|1209,1264|1266,1294|1296,1296 Q:1,7|9,22|25,25|39,40|47,49|51,64|77,80|84,84|88,88|93,104|106,108|116,116|121,121|124,124|133,133|135,146|152,153|160,160|171,172|174,175|177,184|198,200|202,203|215,235|250,259|283,284|287,290|292,292|304,311|315,322|328,329|338,343|346,351|355,356|360,360|363,363|365,370|376,388|391,398|400,400|402,403|406,406|415,422|425,431|442,442|445,456|458,461|463,463|466,466|474,492|518,524|541,541|543,543|559,570|583,588|591,595|600,601|604,628|633,635|640,640|642,642|651,659|661,672|677,677|682,682|695,697|702,703|706,706|710,715|717,728|730,731|736,753|756,770|773,773|775,775|777,782|786,786|789,789|798,815|817,817|834,835|848,849|854,854|860,862|864,887|892,893|896,912|925,930|934,944|946,952|971,971|980,980|982,982|984,997|999,1000|1003,1009|1011,1013|1017,1018|1023,1029|1032,1037|1044,1044|1046,1046|1048,1051|1054,1054|1062,1063|1067,1091|1093,1093|1096,1098|1101,1101|1104,1104|1106,1120|1122,1123|1125,1125|1135,1136|1138,1149|1157,1157|1161,1170|1190,1193|1196,1196|1200,1208|1265,1265|1295,1295|1297,1301 ?EEEEEES?HHHHHHHHHHHHHS--S????---------SS??---?BEE?SSHHHHHHHHHHHH------------HTTS--?B???B?-??HHHHHHHHHHHH-SSS--??---S----S?-T--------T?HHHHHHHHHHHH-----HH------H?---------SS-ST-THHHHHHT-------------TSS?SS-----------HHHHHHHHHHHHHHHHHTTSS--------------HHHHHHHHTT--------------------???TT??TTHH-H-----------HHHHHHHH---HHHHHHTT?????ST--------TTHHHH--HHHHHS--?TT???S??S-EEEEES?????HHHHHHHHHHTTT--SEEEEEEE?S?SS??S--????--HHHHTTTS??BEESSSS---------?B??SSTTHHHHSSTT?SSSS?S??S------?HHHHHHTHHHHHHHHHHTT?------------------------SSEEEEE???----------???S?S---------------HHHHHHHHHHHT?????----???SHHHHH??TTSEE--??TT??SSEEEEESSHHHHHHHHHHHHHHHH----HHS----T-T------??GGGEEEEES?HHHHHHHHHHHT----S--??S------------STT????EE-?S---EETGGG?HHHHHHHHHTTG-GG????HHHHHHHTTSHHHHHHTT??HHHHHHHHHHHHHHT??S?S?HHHHHH---T--T??----??SSSSHHHHHHHHHHHHSS?S----------------TT??----------SS----S????-TTS?SSTHHHHHHHHHHHHHHHHHHHHT----SS?-EEHHHHTTHHHHHHHHH?---???-----SHHHHH---HHHHHHHHHHH-HHHHHHT?---------------??S--------E-E?HHHHHHHHHHHHHH?EE?-TTTTSSS?EEE???TT????EEEEEEE??BTTTSS??????S-S?HHHH--S----??-TT???HHHHHHHHHHHHHHHEEEEEEEEEE?B-?SSS??B??B?HHHHHHHHHHHTTEE?SS?S---------SS?HHHHHHHHHHHH?-----?B-??SSTTSGGGSS-------------------SSTT??S?--GGGHHHHTT?????-------------------------------------------------??S???--------------------??????S?EEHHH 1W36|C PF04260.7_DUF436_seed 34 175 !Q:14,16|19,19|26,26|32,40|60,60|66,67|73,73|86,87|91,91|93,93|96,96|100,100|118,119|122,122|132,134|139,139|141,141|146,147|149,150|163,164|167,169|172,172|174,174 Q:0,13|17,18|20,25|27,31|41,59|61,65|68,72|74,85|88,90|92,92|94,95|97,99|101,117|120,121|123,131|135,138|140,140|142,145|148,148|151,162|165,166|170,171|173,173 HHHHHHHHHHHHHS???TT?EEEEEE?HHHHH?????????HHHHHHHHHHHHHHHHTTT?EEEEE??GGGTT?EEEEHHHHHHTT??EEE?B?BT-TBB?HHHHHHHHHSSSEEEES??TT?BSEEEEESS???GGGB?S?EEEE??S??EETTEEEEEEEE??EE???TT?B? 1V8D|A PF04261.7_Dyp_perox_seed 15 379 !Q:0,0|6,6|8,8|19,21|27,29|46,46|49,55|57,57|61,62|65,66|73,75|78,78|91,94|99,99|103,104|107,113|116,119|124,125|150,150|164,165|176,177|179,179|183,183|185,185|189,191|194,194|204,208|212,214|220,220|231,231|239,239|250,250|254,255|259,259|261,264|267,270|272,272|275,275|278,278|280,280|283,283|286,286|292,294|299,299|303,304|307,308|316,316|318,318|334,334|347,352|355,355|359,359|373,377 Q:1,5|7,7|9,18|22,26|30,45|47,48|56,56|58,60|63,64|67,72|76,77|79,90|95,98|100,102|105,106|114,115|120,123|126,149|151,163|166,175|178,178|180,182|184,184|186,188|192,193|195,203|209,211|215,219|221,230|232,238|240,249|251,253|256,258|260,260|265,266|271,271|273,274|276,277|279,279|281,282|284,285|287,291|295,298|300,302|305,306|309,315|317,317|319,333|335,346|353,354|356,358|360,372|378,378 ?SSSSS?B?SEEEEEEEEE???SHHHH---HHHHHHHHHHHHHHHH?EE??---??S?TTS??SS??TTTTEE??-TT?EEEEEEEGGGGS----GGGT?GGG??TT???????TT????GGGB??SEEEEEEESSHHHHHHHHHHHHHT?TTTEEEEEEEEEE??HHHHHTTTSS??B?TTS?B?STT???TT?HHHHHHHTS?---?TTS???GGGTT?EEEEEEEEEE?HHHHHTS?HHHHHHHHTB?TTT??BTT?S?---TT????T-TT?SS?S-SS?SS?HHHHH???STTG-GGG??EE??EEEEEEE?T-TSSEEEEEEEEEEES?TTTTHHHHHHHH------TT?GGG-GTEEEEEEEEEEE?????S 3MM2|A PF04262.9_Glu_cys_ligase_seed 7 389 !Q:7,8|18,18|30,30|34,34|36,37|39,39|41,41|45,46|50,50|56,56|66,68|71,71|93,94|97,98|102,102|105,106|109,112|114,117|137,137|143,144|152,153|162,162|164,166|197,198|203,203|207,213|215,216|219,227|231,231|234,234|237,237|248,249|256,258|261,261|275,275|277,277|284,284|289,289|293,294|296,296|300,300|306,308|314,317|320,321|330,332|341,342|349,350|368,373 Q:0,6|9,17|19,29|31,33|35,35|38,38|40,40|42,44|47,49|51,55|57,65|69,70|72,92|95,96|99,101|103,104|107,108|113,113|118,136|138,142|145,151|154,161|163,163|167,196|199,202|204,206|214,214|217,218|228,230|232,233|235,236|238,247|250,255|259,260|262,274|276,276|278,283|285,288|290,292|295,295|297,299|301,305|309,313|318,319|322,329|333,340|343,348|351,367|374,388 HHHHHHH--HHSGGGGTT?EEEEEEEEEEE?TTS?B??S?S?GGG??TTT?SSEEE?SBTTEEEEE???BS?HHHHHHHHHHHHHHHHTSSTT-?EE??SSS?SS??TT????B????SSHHHHHHHHHHHHHHHHH?HHHHT??EEEEEEE??HHHHHHHH?S??-HHHHHHHHHHHHHHHHHHHHHHTTHHHHHH??BSEE?GGG???????S??EE?--------TTS?EE?TT?SBGGGSTTSS??GGGTTS???SS?HHHHHHHHHHHHT?B?HHHHTT?SEET-TEE??S?SBS?SSGGG???SEEEE????TT??HHHHHHHH???EEEEEEEE??TTSTTS??HHHHHHHHHHHHHHHHS??????HHHHHHTHHHHHHHH 1VA6|A PF04263.11_TPK_catalytic_seed 16 187 !Q:1,1|3,8|10,10|17,17|20,20|22,22|25,25|35,37|42,58|61,61|65,67|73,74|78,78|80,80|90,91|93,93|98,102|106,106|119,119|125,127|129,129|135,136|140,140|147,153|161,162|165,172|174,174|177,177|180,180 Q:0,0|2,2|9,9|11,16|18,19|21,21|23,24|26,34|38,41|59,60|62,64|68,72|75,77|79,79|81,89|92,92|94,97|103,105|107,118|120,124|128,128|130,134|137,139|141,146|154,160|163,164|173,173|175,176|178,179|181,186 S-S???---T-THHHHH-HH?S?EE-EETTHHHHH---HHHT-----------------TT?GGG???SEEEE??SSS?H-HHHHHHHHT--T?EEEE??--?TTS?HHHHHHHHHHHH-HHHTT???S-EEEEE??SSS-SHHHHH-------HHHHHHH--HG--------G-GT?SS?EEEEET 3S4Y|A PF04264.8_YceI_seed 135 365 !Q:2,5|8,22|27,27|37,41|43,43|49,54|57,57|60,64|67,70|72,75|79,82|85,85|89,89|92,93|101,102|105,106|108,113|115,118|123,124|127,127|132,137|141,141|145,146|154,154|158,166|170,184|187,188|193,194|206,206|212,214|218,218|220,288|291,291|293,293|297,306|315,315|320,320|326,331|333,349|355,355 Q:0,1|6,7|23,26|28,36|42,42|44,48|55,56|58,59|65,66|71,71|76,78|83,84|86,88|90,91|94,100|103,104|107,107|114,114|119,122|125,126|128,131|138,140|142,144|147,153|155,157|167,169|185,186|189,192|195,205|207,211|215,217|219,219|289,290|292,292|294,296|307,314|316,319|321,325|332,332|350,354|356,364 EE----EE--------------?TTTT?EEEEEEEEE-----T-TTEEE------EE-EE?-?--EE----E----EEE?--?SS?GGG?EE--EEEEEGG--GE--E?-----S---?HHHH--HH-HHST------TTT?TTT??EEEEEEE-EEE---------EET---------------TE--EEEE--EEEEETTEEEE-EEEEE---EEE-E---------------------------------------------------------------------EE-E?TTS---------?EEEEEEEE-EEEE-TGGGT??????G-----------------GGSEE-EEEEEEEEE 3Q34|A PF04265.9_TPK_B1_binding_seed 86 106 !Q:2,2|7,11|13,28|36,39|42,42|54,62|64,64|71,72|76,77|82,82|84,90|92,94|104,104 Q:0,1|3,6|12,12|29,35|40,41|43,53|63,63|65,70|73,75|78,81|83,83|91,91|95,103|105,105 EE-EEEE?????E----------------EEEEEEE?--?SS?EEEEEEESBSS??-------S-SEEEBT--TTB-?EEEE?B------?S?--SEEEEEESS?E 3S4Y|A PF04266.9_ASCH_seed 85 215 !Q:1,10|18,24|37,38|51,59|61,61|63,63|68,69|71,103|106,107|118,120|124,127|132,141|147,150|153,154|156,165|168,168|180,184|195,198|201,201|208,209 Q:0,0|11,17|25,36|39,50|60,60|62,62|64,67|70,70|104,105|108,117|121,123|128,131|142,146|151,152|155,155|166,167|169,179|185,194|199,200|202,207|210,214 E?---------SSSSHHH-------HHHHHHHHHTTS??EEEEETHHHHTT??????---T-T?EEEE--E?--------------------------------TT??EEEEEEEEEE---EEE----EGGG?--------?HHHHH----HH??T----------TS?HHHHHHHHHHH-----HHHHHHHHTS-???TT?EEEEEE--EEEEE 1T62|A PF04267.7_SoxD_seed 89 90 !Q:9,9|23,27|29,31|36,36|46,50|60,60|65,66|77,78|82,83 Q:0,8|10,22|28,28|32,35|37,45|51,59|61,64|67,76|79,81|84,89 EEEETTTEE-EEGGGSEEEEESS-????S?--GGGS?HHHHHHHHH?????SSEEEEEEE?TTTT??EEEEEEETTT??EEE--EEETTS 2GAG|D PF04268.7_SoxG_seed 6 160 !Q:1,2|6,7|20,23|31,31|35,35|50,51|54,54|58,58|72,72|77,77|82,83|99,100|102,104|109,109|127,130 Q:0,0|3,5|8,19|24,30|32,34|36,49|52,53|55,57|59,71|73,76|78,81|84,98|101,101|105,108|110,126|131,159 E??TTS--HHHHHHHHHSSS????STTBEEE?TTS?EEEEEETTEEEEEE--SS?THH-HHHHHHHHTTSSS-EEEE?TTTB??EEEESTTHHHHHTTT??S???TTTS?TTEEEEEEETTEEEEEE----EEETTEEEEEEBGGGHHHHHHHHHHHHGG 1WOP|A PF04269.7_DUF440_seed 9 107 !Q:0,0|3,7|23,23|28,28|43,43|49,51|61,63|74,77|80,82|84,84|92,92|98,99|105,106 Q:1,2|8,22|24,27|29,42|44,48|52,60|64,73|78,79|83,83|85,91|93,97|100,104 ?SS?????HHHHHHHHHHHHHHH?STTS?HHHHHHHHHSSSTT?EEEEE???STTTTTTSS???TTSSEEEEEE???-TT???S?EEEEEEE?SSSSS??EEEEE?? 1NNV|A PF04270.8_Strep_his_triad_seed 5 53 !Q:0,0|2,2|6,6|8,9|13,14|17,17|38,38|51,52 Q:1,1|3,5|7,7|10,12|15,16|18,37|39,50 ?B?TTS?B??GGG??EE?SSEEEEEETTEEEEEEGGGS?HHHHHHHHHHHH?- 2CS7|A PF04272.9_Phospholamban_seed 2 52 !Q:0,0|19,19|51,51 Q:1,18|20,50 ?THHHHHHHHHHHHHHHTT?SSTTHHHHHHHHHHHHHHHHHHHHHHHHHHH? 1FJP|A PF04273.8_DUF442_seed 5 110 !Q:0,1|13,15|27,28|33,33|35,35|42,44|57,58|62,65|69,70|85,85|92,92 Q:2,12|16,26|29,32|34,34|36,41|45,56|59,61|66,68|71,84|86,91|93,109 ??EEEETTEEEES???GGGHHHHHHHT??EEEE?S?TTSSTT???HHHHHHHHGGGT??EEE????TTT??HHHHHHHHHHHHTS?SSEEEE?SSSHHHHHHHHHHHHHT 2F46|A PF04275.9_P-mevalo_kinase_seed 11 127 !Q:3,3|20,20|26,27|30,30|45,57|75,75|87,96|102,105|119,122 Q:0,2|4,19|21,25|28,29|31,44|58,74|76,86|97,101|106,118|123,126 EEE?TTSSHHHHHHHHHHHH?TTTEE--EE?THHHHHHHHHHTTT?????????????SSHHHHHHHHHHHHHHH?TTTTHHHHSBT?-------??SEEEE????SHHHHHHHHHHHG----GGEE 3CH4|B PF04278.7_Tic22_seed 13 362 !Q:0,89|91,100|117,117|120,121|123,127|130,130|132,133|135,135|144,144|152,152|159,160|162,174|180,180|184,184|204,213|216,216|223,224|240,243|245,247|249,249|260,263|265,265|284,293|307,307|310,317|334,337|347,348|356,356|360,361 Q:90,90|101,116|118,119|122,122|128,129|131,131|134,134|136,143|145,151|153,158|161,161|175,179|181,183|185,203|214,215|217,222|225,239|244,244|248,248|250,259|264,264|266,283|294,306|308,309|318,333|338,346|349,355|357,359 ?---------------------------------------------------------------------------------------??H----------HHHHHHHTTSEEEEEE?TT??B?????TT-S??S?SEEEEEES?HHHHHHH-HHHHSS??H-------------HHHHH-HTT?EEEEEEHHHHHHHHHHTTT---------?TT?EEEEEE??HHHHHHHHHHHHTTT???-S???S?EEEEEESSTT----S?BEEETTTTEEEEEEESSH----------HHHHHHHHHHTTT?TT-----?--EEEEEEHHHHHHHHHH??-?GGGGGEEEE??HHHHHHH-HTS?? 4E6Z|A PF04280.10_Tim44_seed 140 179 !Q:5,5|7,7|13,13|16,17|41,41|50,50|65,65|70,83|86,87|104,105|121,121|123,123|126,126|129,129|131,131|136,140|143,144|156,160|163,163|165,165|167,167|170,170 Q:0,4|6,6|8,12|14,15|18,40|42,49|51,64|66,69|84,85|88,103|106,120|122,122|124,125|127,128|130,130|132,135|141,142|145,155|161,162|164,164|166,166|168,169|171,178 HHHHH-H-HHHHH?TT??HHHHHHHHHHTHHHHHHHHHHHT?HHHHHHHB?HHHHHHHHHHHHHH-HHTT-------------?EE??EEEEEEEEEEEEEEEE--TTEEEEEEEEEEEEE?E-EE?TT-S?EEEE----?TT??EEEEEEEEEEE?----TT?S?G-GG?EEEEEEEE 3QK9|A PF04287.7_DUF446_seed 56 108 !Q:2,2|4,4|21,28|35,36|39,39|44,44|65,69|72,74|83,84|87,90 Q:0,1|3,3|5,20|29,34|37,38|40,43|45,64|70,71|75,82|85,86|91,107 HH-H-HHHHHHHHHHHHHHTT????????GGGTTT??SS?TTTS?THHHHTTTHHHHHHHHHHTT???-?TT???HHHHHHHS?-TT?---TTHHHHHHHHHHHHHHH 2HGK|A PF04288.8_MukE_seed 3 238 !Q:0,1|24,25|27,27|58,58|62,62|68,68|71,71|74,74|78,79|95,95|119,119|131,131|134,134|161,161|163,163|172,172|187,187|202,208|211,237 Q:2,23|26,26|28,57|59,61|63,67|69,70|72,73|75,77|80,94|96,118|120,130|132,133|135,160|162,162|164,171|173,186|188,201|209,210 ??HHHHHHHHSTTHHHHHHHHHTT??B?TTSHHHHHHHHHHHHHHHHHHHTTTEEEEE?TTS?EEEEE?TT?SS?EEE??HHHHHHHHHHHHHHH?GGGGGGTTEEEHHHHHHHHHHHS?HHHHHHHHSSS?SS?HHHHHHHHHHHHHHHHHHHHTTSEEE?S-SSSSEEEE?GGGGGGGHHHHSSS?HHHHHHHHHHTTSE-------EE???????--???????????---???? 3EUK|L PF04289.7_DUF447_seed 45 215 !Q:0,0|8,8|11,13|20,21|25,26|31,33|38,40|53,53|60,62|73,76|78,78|84,84|86,86|88,88|92,94|100,100|112,121|123,123|127,128|140,140|142,150|152,152|167,167|169,171|173,180|199,200|204,205 Q:1,7|9,10|14,19|22,24|27,30|34,37|41,52|54,59|63,72|77,77|79,83|85,85|87,87|89,91|95,99|101,111|122,122|124,126|129,139|141,141|151,151|153,166|168,168|172,172|181,198|201,203|206,214 ?BEEEEEE?TT-??EEEEEE??EEE??SSTT???EEEE???TTSHHHHHHHHH?EEEEEE???HHHHHHHHHS????T-TSEEE?T-T?TTT?--EEESS?SEEEEEEEEEE----------E?STT??EEEEEEEEEEE?S-----????B?HHHHHHHHHHHHHT?S---S?-----??HHHHHHHHHHHHHHHHHH??HHH--HHHHHHHHH 3B5M|A PF04296.8_DUF448_seed 155 122 !Q:0,1|3,3|7,9|11,12|22,22|25,28|30,35|40,41|45,47|54,54|57,57|60,61|68,72|75,76|85,86|88,105|108,109|114,116 Q:2,2|4,6|10,10|13,21|23,24|29,29|36,39|42,44|48,53|55,56|58,59|62,67|73,74|77,84|87,87|106,107|110,113|117,121 ??B?TTT??-B??GGGEEEEEE?TT----S----?-EEEE--TTS???SEEEEE-ES?HH--HHHHHH-----HH--THHHHHHT--S?-------------??--HH--HHHH---HHHHH 1G2R|A PF04297.9_UPF0122_seed 9 101 !Q:18,18|32,34|44,45|68,68|86,86|89,92 Q:0,17|19,31|35,43|46,67|69,85|87,88|93,100 HHHHHHHHHHHHHHGGGS?HHHHHHHHHHHTS???HHHHHHHTT??HHHHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHHHTT?TT?---HHHHHHHH 1XSV|A PF04299.7_FMN_bind_2_seed 129 255 !Q:0,13|24,24|30,43|45,45|47,50|55,57|65,65|68,71|74,85|91,92|103,105|108,124|126,126|129,132|141,141|146,146|151,155|157,158|160,163|179,184|187,192|207,207|209,218|220,237 Q:14,23|25,29|44,44|46,46|51,54|58,64|66,67|72,73|86,90|93,102|106,107|125,125|127,128|133,140|142,145|147,150|156,156|159,159|164,178|185,186|193,206|208,208|219,219|238,254 ????????--????THHHHHHHHS?EEEEE--------------E-E----ETTE---EEEEEEE?EE?---TT------------SSEEE--EEEETTSGGG---GG?----------------T-TS-?--EEEEEEEE-EEEE?GGGS-----S?-S????EEEEEEEEEEEEEEE??---?HH------HHHHHHHHHHHHHS?T----------T????---???????--??THHHHSEEEEEEEEEEE 2OL5|A PF04300.8_FBA_seed 6 218 !Q:10,10|12,13|16,16|20,48|55,55|60,60|62,62|65,67|77,80|82,82|85,86|91,92|95,95|109,110|118,119|129,130|134,134|148,148|163,163|166,170|179,179|181,182|199,200|204,204|206,206|217,217 Q:0,9|11,11|14,15|17,19|49,54|56,59|61,61|63,64|68,76|81,81|83,84|87,90|93,94|96,108|111,117|120,128|131,133|135,147|149,162|164,165|171,178|180,180|183,198|201,203|205,205|207,216 HHHHHHHHHH?S??SS?SSS-----------------------------SSTTTT?EEEE-E?TT???EEESSBTTB????S?SS??EEEE??SS?EEEEEEEETTTTT??HHHHTTT??EEEEEEEEE??SSS?EEEEEEEEEEETT-TEEEEEEEEEEEEE?TT??---EEEEEEEE?S??TTEEEEEEEEEEEESS??SSS?S?EEEEEEEEEE? 2E32|A PF04303.8_PrpF_seed 6 387 !Q:24,24|44,44|46,46|51,51|56,57|63,63|71,72|76,76|86,86|91,91|94,94|96,98|114,114|116,116|120,121|151,154|157,158|161,161|164,164|166,167|175,182|184,184|190,190|224,225|227,229|236,236|257,257|266,267|277,280|283,283|286,287|290,290|294,294|307,307|310,311|337,339|374,374 Q:0,23|25,43|45,45|47,50|52,55|58,62|64,70|73,75|77,85|87,90|92,93|95,95|99,113|115,115|117,119|122,150|155,156|159,160|162,163|165,165|168,174|183,183|185,189|191,223|226,226|230,235|237,256|258,265|268,276|281,282|284,285|288,289|291,293|295,306|308,309|312,336|340,373|375,386 EEEEEEEEEEETTEEEEEEEGGGS?GGGSSSSHHHHHHHHHHHT?S?TTSS?TTSS??SSGGG?EEEEEEE??STT?SEEEEEEEE?SSSS?EE?S???HHHHHHHHHHHHHTT?S?GGG??SSEEEEEEEEETTTTEEEEEEEEEETTEE????SB??TT?SS?B??EEEEEES????????S?SSTTS?SSEEEEETTTEEEEEEEEESSSEEEEEETTTTT??S???THHHHT?HHHHHHHHHHHHHHHHHTTS?SSGGGGGG??SSSEEEEEE????EE?SS??EE?GGG?SEEEEEEETTEE?SS??HHHHHHHHHHHHSTTSHHHHHTTSS?-?SEEEEEETTEEEEEEEEEEEETTEEEEEEEEEEE?EEEEEEEEEEEE 2H9F|A PF04309.7_G3P_antiterm_seed 8 192 !Q:0,2|10,10|14,18|25,26|44,44|56,57|60,60|72,73|80,80|92,93|100,101|118,118|141,143|149,151|169,184|186,187 Q:3,9|11,13|19,24|27,43|45,55|58,59|61,71|74,79|81,91|94,99|102,117|119,140|144,148|152,168|185,185|188,191 ???EEEEEES?SSS?????SSEEEE??EETTTHHHHHHHHHHTT?EEEEEGGGEET??SS-HHHHHHHHHHT-?SEEEES?HHHHHHHHHTT??EEEEEE??SHHHHHHHHHHHHHHT?SEEEEESGGGHHHHHTTSTTSE---EEEES???SHHHHHHHTTTSSEEEE-------------??-H--HHHT 3KTS|A PF04310.7_MukB_seed 2 227 !Q:0,4|23,23|34,35|52,53|57,76|81,81|93,93|97,97|108,108|114,114|125,126|129,130|138,139|143,144|147,148|162,162|167,167|169,169|186,188|208,208|222,226 Q:5,22|24,33|36,51|54,56|77,80|82,92|94,96|98,107|109,113|115,124|127,128|131,137|140,142|145,146|149,161|163,166|168,168|170,185|189,207|209,221 ?????EEEEEEEEEETTEEEEEE?HHHHHHHHHS??SHHHHHHHHHHHHHHS??TTT????????????????????GGGB?SSEEEEEEEEE?TTS?EEEEEEEEEE?SSTTT?EEEEEEEEES??TT??HHHHHEE??SSS??EE??HHHHHHHHHTSTT?EEEE?S?HHHHHHHHHHTTSBSS???SHHHHHHHHHHHHHHHSSS?HHHHHHHHHHHBS????? 3EUJ|A PF04313.9_HSDR_N_seed 77 381 !Q:0,0|9,11|18,18|23,23|26,46|65,82|95,96|99,100|111,113|119,120|123,124|131,136|143,171|173,173|179,221|230,252|262,263|265,274|276,276|278,283|290,291|293,308|315,359|365,365|368,368|374,375|377,377 Q:1,8|12,17|19,22|24,25|47,64|83,94|97,98|101,110|114,118|121,122|125,130|137,142|172,172|174,178|222,229|253,261|264,264|275,275|277,277|284,289|292,292|309,314|360,364|366,367|369,373|376,376|378,380 ?SSHHHHHH---HHHHHH-HHTT?EE-----------------????SHHHHHHHHHHHHHHHHT?--------------???HHHHHHHHHHTT??TT??HHHHHHHHHT?-?EEEEE?-TT??EEEEES----??SSSGGG-----------------------------S?EEEEE?????--------------------------------??????EEEEEEET-----------------------TEEEEEEEE??T----------T-S-----?HHHHHH--H-???????????---?SGGGGG?-------------------------------------------?EEEEE?SS?EEEEE??S?STT 3H1T|A PF04314.8_DUF461_seed 175 195 !Q:0,2|7,22|26,58|60,65|71,71|76,77|81,81|83,83|90,91|93,93|95,95|119,119|121,122|126,126|129,129|134,139|142,145|147,148|155,155|158,159|161,162|165,165|174,175|179,184|187,190|195,195 Q:3,6|23,25|59,59|66,70|72,75|78,80|82,82|84,89|92,92|94,94|96,118|120,120|123,125|127,128|130,133|140,141|146,146|149,154|156,157|160,160|163,164|166,173|176,178|185,186|191,194 ???EEEE?---------------BSS---------------------------------S------EEEEE-EEEE??SSS?E-EEEEEE-?T-T?SEEEEEEEEEEEETTEEEEEEEE?S-?EEE?TT?EEEE-----?TT----S-?EEEEES?SS?-B-?TT?EEEEEEEE--TTT------EE----EEEE- 2K70|A PF04316.8_FlgM_seed 135 84 !Q:12,12|15,44|46,49|67,71 Q:0,11|13,14|45,45|50,66|72,83 HHHHHHHHHHHH-TT------------------------------T????SSHHHHHHHHHHHHHTT?????HHHHHHHHHHHH 1RP3|B PF04321.12_RmlD_sub_bind_seed 37 350 !Q:0,0|2,2|7,7|23,23|26,26|32,33|36,42|46,49|61,69|73,74|76,77|82,87|95,95|116,116|120,120|132,142|146,147|149,149|153,157|174,175|177,177|179,179|187,187|191,192|194,196|199,202|212,213|216,216|225,225|228,229|249,249|253,257|262,264|267,271|290,294|296,297|303,303|308,309|312,314|317,318|320,321|330,333|335,335|349,349 Q:1,1|3,6|8,22|24,25|27,31|34,35|43,45|50,60|70,72|75,75|78,81|88,94|96,115|117,119|121,131|143,145|148,148|150,152|158,173|176,176|178,178|180,186|188,190|193,193|197,198|203,211|214,215|217,224|226,227|230,248|250,252|258,261|265,266|272,289|295,295|298,302|304,307|310,311|315,316|319,319|322,329|334,334|336,348 ?E-EEEE?TTSHHHHHHHHHTTT-TS-EEEEE-?TT------?SSS-???TTSHHHHHHHH---------HHH??S--EEEE??????TTHHHHS-HHHHHHHHTHHHHHHHHHHH-HTT?EEEEEEEGGGS???--------SSS?-B?TTS?????SHHHHHHHHHHHHHHH--H?S-SEEEEEE?SEE-?S---SS?--?HHHHHHHHH--HH?SEEEEESS?EE??EEHHHHHHHHHHHHHHHHH?GGG----?EEEE???BS?----EEHHHHHHHHHHHHHHTT--???S??EEEEE?STTS??SS???SB??B??HHHHHHHT????B-HHHHHHHHHHHHH? 1DB3|A PF04324.10_Fer2_BFD_seed 190 119 !Q:0,0|3,4|20,40|44,60|62,66|75,75|77,89|94,95|101,103|106,111 Q:1,2|5,19|41,43|61,61|67,74|76,76|90,93|96,100|104,105|112,118 ?EE--ETTTTEEHHHHHHHH---------------------HTT------------??---S-----HHHHHHHH?T-------------TSSS?-TTHHH---HH------HHHHHHH 4E6K|G PF04325.8_DUF465_seed 175 67 !Q:10,10|16,17|24,31|33,33|49,57 Q:0,9|11,15|18,23|32,32|34,48|58,66 HHHHHHHHHH-HHHHH--HHHHTT---?----S?HHHHHHHHHHHHHHH---------HHHHHHHHH 1ZHC|A PF04326.9_AAA_4_seed 163 299 !Q:1,1|5,5|9,9|17,36|47,47|50,61|70,72|74,78|81,81|84,85|91,116|137,152|157,162|169,231|238,243|245,248|252,275|280,284|286,290|292,298 Q:0,0|2,4|6,8|10,16|37,46|48,49|62,69|73,73|79,80|82,83|86,90|117,136|153,156|163,168|232,237|244,244|249,251|276,279|285,285|291,291 S?SSE-EEE?GGGTTHH--------------------HHHHHHHHHT?TT---??-----?-EEEEESEE---E-----EE?TT??EEEEE???-----------------------SSHHHHHHHHHHHHHHTBSS?-----------???-EEEE------EEETTE---------------------------------------------------------------EEEEEE------E????STT--------------------????BSSS?????S?????S????-?? 3LMM|A PF04327.7_DUF464_seed 58 138 !Q:0,0|8,8|12,12|21,21|24,43|49,53|74,75|77,78|84,85|89,89|95,96|99,100|127,127|130,134 Q:1,7|9,11|13,20|22,23|44,48|54,73|76,76|79,83|86,88|90,94|97,98|101,126|128,129|135,137 ?EEEEEEE?TTS?EEEEEEES?SS-----------??------?SSHHH-----HHHHHHHHHHHHHHHHHHHT-?S??EEEEE-?STT?EEEEE??TT??HHHHHHHHHHHHHHHHHHHHHHHHTT-TT-----EEE 2IDL|A PF04335.8_VirB8_seed 104 276 !Q:0,96|112,112|116,117|119,119|124,124|126,127|137,138|140,140|152,156|160,162|164,164|173,173|176,178|186,186|189,193|196,200|202,207|211,211|219,220|222,231|235,235|246,248|253,254|261,261|264,264|275,275 Q:97,111|113,115|118,118|120,123|125,125|128,136|139,139|141,151|157,159|163,163|165,172|174,175|179,185|187,188|194,195|201,201|208,210|212,218|221,221|232,234|236,245|249,252|255,260|262,263|265,274 ----------------??---------------------------------------------------??????????????----???----???HHHHHHHHHHHHHHH-HHH?-B?TTTH-H--HHHHHHHHT--B?HHHHHHHHGGG-----SSS---S?HHHHHTTT?EE---EEEEEEE-EE?----SS-----S------EEE-EEEEEEE--E??????--??EEE-EEEEEEEEEE??-GGGS-?HHHHTT?TT?EEEEEEEEEE? 2BHM|A PF04337.7_DUF480_seed 53 158 !Q:1,1|18,18|22,22|35,35|39,39|42,46|66,68|70,71|74,75|80,80|85,88|91,92|106,106|109,109|122,123|141,146|152,154|157,157 Q:0,0|2,17|19,21|23,34|36,38|40,41|47,65|69,69|72,73|76,79|81,84|89,90|93,105|107,108|110,121|124,140|147,151|155,156 B?HHHHHHHHHHHHHHHH?GGG?SEEHHHHHHHHT?SSS?SS?????HHHHHHHHHHHHHTTSEEE---E??SS??EEEE?HHHH----HT??HHHHHHHHHHHHH?SB?HHHHHHHHTTTS??SSHHHHHHHHHHHHHHT------SEEEE???TT? 3BZ6|A PF04340.7_DUF484_seed 6 233 !Q:0,42|90,91|109,110|119,119|122,124|129,134|136,136|151,153|157,159|167,169|175,176|185,187|227,228|230,232 Q:43,89|92,108|111,118|120,121|125,128|135,135|137,150|154,156|160,166|170,174|177,184|188,226|229,229 ??-????????????????????????????????????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??SHHHHHHHHHHHHHHTS??SEEEEEEE?SS???SSEE------E?HHHHHHHHHHHHTT???STT???HHHHHHH???TTGGG??EEEEEEEE---SSSEEEEEEEEESSTTGGGSTTTTHHHHHHHHHHHHHGG--G??? 3E98|A PF04344.8_CheZ_seed 60 230 !Q:28,34|95,96|100,103|118,118|166,217|228,229 Q:0,27|35,94|97,99|104,117|119,165|218,227 HHHHHHHHHHHHHHHHHHHHHHTHHHHH-------HHTTTTHHHHHHHTTTHHHHHHHTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSS??HHH----HHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHTTTTTT???????????????---------------????-??????-??????????SHHHHHHHHH?? 1KMI|Z PF04345.8_Chor_lyase_seed 3 180 !Q:7,7|9,9|12,16|25,25|28,28|38,40|52,56|66,68|70,71|98,98|108,108|112,114|122,122|134,135|137,145|168,168|174,179 Q:0,6|8,8|10,11|17,24|26,27|29,37|41,51|57,65|69,69|72,97|99,107|109,111|115,121|123,133|136,136|146,167|169,173 HHHHHHT?E?SS?????HHHHHHHT?SS?SHHHHHTTT?-?EEEEEEEEEEE----?GGGTTGGGS???S?-EEEEEEEEEETTEEEEEEEEEEEGGG?SGGGGGGGG?TTS???GGGGSSS?EEEEEEEEEEE--T---------TEEEEEEEEEETTEEEEEEEEE?TTSTT?----- 1TT8|A PF04348.8_LppC_seed 6 585 !Q:0,226|232,233|253,258|261,262|264,264|270,270|275,277|290,291|295,297|308,308|311,311|316,316|322,324|327,332|338,341|358,359|361,361|389,391|408,433|436,437|440,441|446,448|462,465|467,467|470,470|475,475|479,480|486,486|496,496|501,501|506,508|514,515|519,519|525,525|552,552|555,556|567,567|570,570|576,576 Q:227,231|234,252|259,260|263,263|265,269|271,274|278,289|292,294|298,307|309,310|312,315|317,321|325,326|333,337|342,357|360,360|362,388|392,407|434,435|438,439|442,445|449,461|466,466|468,469|471,474|476,478|481,485|487,495|497,500|502,505|509,513|516,518|520,524|526,551|553,554|557,566|568,569|571,575|577,584 --------------------------------------------------------------------------------------?-----------------------------------------------------------------------------------------------------------------------------------------???EEEEE??SSTTHHHHHHHHHHHHHHH------TT??S?EEEEE-TTTS--?HHHHHHHHHHTT??EEE???SHHHHHHHHH?GG-GGTT?EEEES???TT?-??-?TTEEE????HHHHHHHHHHHHHHTT??S?EEEEESSHHHHHHHHHHHHHHHHHHSS?-?EEEEESSTTHHHHHHH--------------------------HS?-TT??EEEE???HHHHHHHHHHHTT----T?TT?EEEE?GGG??HHHHT?HHHHHHTTT?EEEE?GGGG???SHHHH--HHH-HHTTT?HHHHHHHHHHHHHHHHHHTHHHHHHS-TT??EEETTEEEEE?TT?BEEEE?EEEEEETT 3CKM|A PF04349.7_MdoG_seed 4 495 !Q:0,1|16,32|39,39|42,42|46,46|53,53|55,55|62,62|67,67|69,69|76,76|79,79|83,86|92,92|94,94|97,99|106,107|116,116|119,119|122,123|125,125|139,140|143,147|152,152|158,158|161,162|164,165|174,176|179,181|203,203|220,221|223,223|232,232|240,241|244,245|247,247|249,249|253,254|260,260|264,264|270,273|276,276|286,287|293,297|302,303|307,307|311,312|321,323|332,334|336,336|340,341|350,353|356,356|369,369|375,375|390,390|393,395|398,401|412,412|419,419|422,424|431,431|440,440|461,461|463,463|466,466|475,476|490,493|495,495 Q:2,15|33,38|40,41|43,45|47,52|54,54|56,61|63,66|68,68|70,75|77,78|80,82|87,91|93,93|95,96|100,105|108,115|117,118|120,121|124,124|126,138|141,142|148,151|153,157|159,160|163,163|166,173|177,178|182,202|204,219|222,222|224,231|233,239|242,243|246,246|248,248|250,252|255,259|261,263|265,269|274,275|277,285|288,292|298,301|304,306|308,310|313,320|324,331|335,335|337,339|342,349|354,355|357,368|370,374|376,389|391,392|396,397|402,411|413,418|420,421|425,430|432,439|441,460|462,462|464,465|467,474|477,489|494,494 ??HHHHHHHHHHHHTS?????????????????HHHHTT?EE?GGG?BTTTSS?S?EEEEEE?BTTB?S?BEEEEE?SS?EEE????GGGEE?T-TS???TTTSTT??EEEEEEEE?SS?TT??E-EEEEEESTTEEEE??TT?????EEES?EESTT?TT??B??EEEEEEEE???TT???EEEEEEEEETTEEEEEEEEEE?SSSEEEEEEEEEEESS??S?EEEEEEEE?EEEBTTB??SS??S?S?EES??EEEEE?TTS?EEEEE????SS?EEEEEEEES??EEEEE?????GGGT??TTT?GGG??EEEEEESS???EEEEEEEE???S?TTS??EEEEEEES????TT?EEEEEEEEEEES?GGGGS?TTSBEEEEEEEEES?TT???TT????SEEEEEEEEE?TTGGGS?TT???EEEEEE?TTEEEEEE-EEEEETTTTEEEEEEEEEES?T-TS?EEEEEEEE?-SSSEEEEEEEEEE?---T- 1TXK|A PF04350.8_PilO_seed 75 164 !Q:0,12|24,24|70,70|78,81|84,86|101,101|118,118|120,121|132,135|139,146|162,163 Q:13,23|25,69|71,77|82,83|87,100|102,117|119,119|122,131|136,138|147,161 ?-----------?HHHHHHHTGGG?SSHHHHHHHHHHHHHHHHHHHHTTTGGGHHHHHHHHHHHHHHHTT?EEEEEEE??-?EE--?SSEEEEEEEEEEEE?HHHHHHHHHHHHTSSS?E--EEEEEEEEES----STT-------?SSSEEEEEEEEEEEE?? 2RJZ|A PF04351.8_PilP_seed 54 175 !Q:0,88|94,94|105,109|113,114|121,121|129,129|157,158|161,161|173,174 Q:89,93|95,104|110,112|115,120|122,128|130,156|159,160|162,172 ???????????????????????????????????-?????----------------??????????????????-----?????---?GGGGS?STTEEEEEEE---?-SSS??EEEEEE-TTEEEEE?SSEEETTTTEEEEEEETTEEEEEEEEE?-SS-SSEEEEEEEEE?? 2LC4|A PF04352.8_ProQ_seed 46 123 !Q:3,4|6,6|17,17|26,27|29,30|32,32|48,48|50,52|73,75|78,78|82,82|86,86|91,92|109,109|119,121 Q:0,2|5,5|7,16|18,25|28,28|31,31|33,47|49,49|53,72|76,77|79,81|83,85|87,90|93,108|110,118|122,122 GSS??H-HHHHHHHTTT?GGGEETTE--E??B?TTHHHHHHHHHHHTT?S-??HHHHHHHHHHHHTSHHHHHH?-?TT?EEE?TTS?EEEE??HHHHHHHHHHHHHHHH-HHHHHHHHH---H 3MW6|A PF04353.8_Rsd_AlgQ_seed 45 159 !Q:0,0|15,15|38,54|83,84|88,90|119,119|125,126 Q:1,14|16,37|55,82|85,87|91,118|120,124|127,158 ?HHHHHHHHHHHTTS?HHHHHHHHHHHHHHHHHHHHHS????----?????????HHHHHHHHHHHHHHHHHHHTHHHHHHTT??SHH---HHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHS??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 2P7V|A PF04354.8_ZipA_C_seed 59 151 !Q:2,2|8,8|11,11|15,16|31,31|34,34|47,51|54,54|56,56|68,73|76,77|81,81|94,94|97,98|118,118|120,120|124,124|128,128|130,131|133,140 Q:0,1|3,7|9,10|12,14|17,30|32,33|35,46|52,53|55,55|57,67|74,75|78,80|82,93|95,96|99,117|119,119|121,123|125,127|129,129|132,132|141,150 SS?EEEEE-EE?STT??EEHHHHHHHHHHTT?EE-ETTTEEEEESST-----TS?S?EEEEEEESSTT?--???GG--GGS?EESEEEEEEESS?SS-?HHHHHHHHHHHHHHHHHHH-T?EEE?TTS?B??H--------HHHHHHHHHH 1F46|A PF04355.8_SmpA_OmlA_seed 146 92 !Q:0,0|3,4|11,12|15,15|26,28|32,33|37,37|39,39|43,43|45,47|49,58|61,69|71,74|82,82 Q:1,2|5,10|13,14|16,25|29,31|34,36|38,38|40,42|44,44|48,48|59,60|70,70|75,81|83,91 ?SS??HHHHHH??TT-SBHHHHHHHH???TTS-?GGG?S-EEE-E???S???-----?-SS---------S?--?EEEEEEE?TTSBEEEEE 2KXX|A PF04356.7_DUF489_seed 56 233 !Q:23,26|30,34|44,45|47,47|49,53|62,62|64,66|82,89|100,104|141,143|145,156|179,183|185,185|191,191|217,218 Q:0,22|27,29|35,43|46,46|48,48|54,61|63,63|67,81|90,99|105,140|144,144|157,178|184,184|186,190|192,216|219,232 HHHHHHHHHHHHHHHHHHHHHHS??-?HHH-----HHHHHHHHH??S?S-----SHHHHTTS?G---GGGHHHHHHHHHHHH-----???SSSHHHHHHH-----HHHHHHHHHHHHHHSTTHHHHHHHHHHTTHHHHTTS--?T------------TSHHHHHHHHHHHHHHTGGGSS?????S?HHHHT?HHHHHHHHHHHHHHHHHHHHHHHTT??HHHHHHHHHHHHHH 1SDI|A PF04358.8_DsrC_seed 87 135 !Q:17,19|22,24|35,35|37,45|47,55|73,82|98,101|105,107|112,112|114,114|116,116|127,134 Q:0,16|20,21|25,34|36,36|46,46|56,72|83,97|102,104|108,111|113,113|115,115|117,126 EEEETTEEEEEETTTEE??-TT???HHHHHHHHHT-T---------T??-----??HHHHHHHHHHHHHHHHH?---??-?-?HHHHHHHHHHHHSSS???-HHH---HHHH?T-T?HHHHHHHHHT???????? 3OR2|C PF04359.9_DUF493_seed 166 116 !Q:2,2|5,11|20,41|44,45|50,51|61,61|63,65|67,69|74,74|78,78|87,87|90,91|106,107|111,111|115,115 Q:0,1|3,4|12,19|42,43|46,49|52,60|62,62|66,66|70,73|75,77|79,86|88,89|92,105|108,110|112,114 SS?SS-?????-EEEEEEEE----?----------------?TT--HHHH--HHHHHHHHS-S---S???EEEE-ESS?SSEEEEEE-EE??SSHHHHHHHHHHHS-?SSS?EEE? 1RWU|A PF04362.9_Iron_traffic_seed 65 91 !Q:0,4|18,18|21,21|35,35|56,57|79,90 Q:5,17|19,20|22,34|36,55|58,78 ??--?EEEETTTTEEEEB?SS?SSSSHHHHHHHHH?BHHHHHHHHHHHHHHHHHHT??TTSHHHHHHHHHHHHHHTSSS?-?????????? 1XS8|A PF04364.8_DNA_pol3_chi_seed 151 171 !Q:0,2|10,10|12,15|19,21|23,23|41,43|48,48|64,64|68,71|75,76|79,79|81,82|86,91|97,97|101,105|107,109|111,112|117,119|122,125|131,132|140,140|145,145|159,159|162,164 Q:3,9|11,11|16,18|22,22|24,40|44,47|49,63|65,67|72,74|77,78|80,80|83,85|92,96|98,100|106,106|110,110|113,116|120,121|126,130|133,139|141,144|146,158|160,161|165,170 ?--EEEEEEE?S????BTT---B?HHHHHHHHHHHHHHHTT??-EEEE?SSHHHHHHHHHHHHH?STT????EEE--TT?S--STT?---?-SEEEE?TTS?--??S-??S--EEEE?-?SS?--?GGGGG?-SEEEEEE?SSHH-HHHHHHHHHHHHH-HT---TEEEEE 1EM8|A PF04365.8_DUF497_seed 96 113 !Q:0,1|4,4|14,14|16,17|20,23|25,28|36,51|57,59|65,65|71,71|86,89|92,96|107,112 Q:2,3|5,13|15,15|18,19|24,24|29,35|52,56|60,64|66,70|72,85|90,91|97,106 ??HH-HHHHHHHHH-S??GG----G??--HHHHHTS----------------EEEEE---ETTEE-EEEEE-ETTTEEEEEEEEEE----TT-----TEEEEEEEEE?????? 3U97|A PF04371.10_PAD_porph_seed 22 396 !Q:0,0|2,4|8,8|15,19|24,25|47,55|57,57|63,63|67,69|78,78|80,88|95,97|100,101|107,107|112,124|127,128|134,135|147,148|164,165|171,176|179,180|187,187|201,201|205,205|209,209|222,224|231,233|236,239|245,245|263,265|284,284|286,286|290,290|292,292|299,300|302,304|306,307|315,317|321,324|327,327|329,332|335,336|347,350|382,382|385,386|396,396 Q:1,1|5,7|9,14|20,23|26,46|56,56|58,62|64,66|70,77|79,79|89,94|98,99|102,106|108,111|125,126|129,133|136,146|149,163|166,170|177,178|181,186|188,200|202,204|206,208|210,221|225,230|234,235|240,244|246,262|266,283|285,285|287,289|291,291|293,298|301,301|305,305|308,314|318,320|325,326|328,328|333,334|337,346|351,381|383,384|387,395 ?B???TTS?EEEEEE?????TTTS--TGGGHHHHHHHHHHHHHHHTT---------S?EEEEE?GGG---HHHHHHHS?T---------TSEEEE???SS??HHHHS?EEEE?????????????EE--EEEEE??TTTHHHHSSBS??TTHHHHHHHHHHHHT??EEEEE------EE??GGGEEE?SSSEEEEEHHHHT?TTT?TTS?HHHHHHHHHHHH???EEEEES???TT?---TTTTS?GGGTEEEEETTEEEEEE???TTSHHHHHHHHHHHHHTT?B?TTS?B?EEEEEE??S-??B??HHHHHTS???SSB????TT?B????TT??EEETTEEEEE????TTHHHHHHHHHHHHSTTSEEEEETTTHHHHT-TT??TGGGEEEEE- 2JER|A PF04378.8_RsmJ_seed 8 264 !Q:2,3|10,11|26,26|38,41|44,45|64,73|77,77|87,87|90,90|96,98|112,112|119,119|121,121|130,130|132,132|135,139|141,141|147,151|155,155|171,171|174,174|200,202|212,214|219,220|229,230|249,249|252,253|262,262 Q:0,1|4,9|12,25|27,37|42,43|46,63|74,76|78,86|88,89|91,95|99,111|113,118|120,120|122,129|131,131|133,134|140,140|142,146|152,154|156,170|172,173|175,199|203,211|215,218|221,228|231,248|250,251|254,261|263,263 SS??EEEESS??SSEEESSSHHHHHH?GGGGTGGGTTT?---TT??GGGHHHHHHHHHTTTTSS--------??EEE?HHHHHHHHS?TT?EEEEE???TTHHHHHHHHTTT?TTEEEE?S?HHHHHHHS?S?TT-----S?EEEEE?????STT-HHHHHHHHHHHHHHH?TT?EEEEEEEESSHHHHHHHHHHHHTTT???EEEEEEESS???SSSS??EEEEEEES??TTHHHHHHHHHHHHHHHH?TT??SEEEEEEE-E 2FHP|A PF04379.9_DUF525_seed 147 128 !Q:0,8|12,12|19,20|31,38|40,40|44,50|55,62|70,71|75,76|88,90|93,93|96,97|123,125 Q:9,11|13,18|21,30|39,39|41,43|51,54|63,69|72,74|77,87|91,92|94,95|98,122|126,127 ?--------GGG?BGGGTB--EEEEEEEEEE--------E?SSS-?-----EEEE--------EEEEEEE-?TTS-?EEEEEEESSSS???EE?TT?-EEEEEEEEEESSSEEEEEEEEEEEE---TT 1XQ4|A PF04381.7_RdgC_seed 71 320 !Q:0,4|15,19|32,36|39,39|47,47|53,56|76,77|97,101|120,120|141,142|144,144|159,159|162,165|168,169|171,172|176,176|189,191|205,205|207,207|212,212|219,220|225,227|237,238|257,261|265,265|272,272|283,284|287,287|316,316|318,319 Q:5,14|20,31|37,38|40,46|48,52|57,75|78,96|102,119|121,140|143,143|145,158|160,161|166,167|170,170|173,175|177,188|192,204|206,206|208,211|213,218|221,224|228,236|239,256|262,264|266,271|273,282|285,286|288,315|317,317 ??--?SSBEEEEESS?????HHHHHHHHHTTB?????TT?SEEEEEE?TTGGG???-SEEESSSEEEEEEEEEEEE??HHHHHHHHHHHHHHHHTTS?????SSSTTHHHHHHHHHHTTT?EEEEEEEEEEEETTTTEEEE??S?HHHHHHHHHHHHHH-HS-???EE--E??BSS?HHHHHHHHHHHT-??STTEEEEEEEEEE?S-STTS?EEEEES??SSSH---HHHHHHHTT-?EEEEEEEEETTTEEEEEE-----TTS?EEEEEE?HHHHSTTTTS-?SS?HHHHHHHHHHHHHHHHHHHHHHHHHHTT?B?? 2OWY|A PF04383.8_KilA-N_seed 139 210 !Q:10,10|15,15|17,21|32,35|37,38|43,49|62,62|66,66|69,154|157,165|167,168|170,172|175,175|177,177|190,190|198,209 Q:0,9|11,14|16,16|22,31|36,36|39,42|50,61|63,65|67,68|155,156|166,166|169,169|173,174|176,176|178,189|191,197 EEEETTEEEE-EETT-T?---?EEHHHHHHHT----T??HHHH-------HHHHTTTGGGSS?EEE?SS-------------------------------------------------------------------------------------?TT---------T?-E---EE-E?HHHHHHHHHHTT?HHHHTTT???????????? 1BM8|A PF04384.8_Fe-S_assembly_seed 61 71 !Q:1,1|4,4|16,16|19,19|21,21|25,29|40,43|47,47|49,49|52,54|70,70 Q:0,0|2,3|5,15|17,18|20,20|22,24|30,39|44,46|48,48|50,51|55,69 B?SS?HHHHHHHHHHH?TT-S?TTT---??HHHHHHHHHH?---SSB?S?SS???HHHHHHHHHHHHHHH? 2BZT|A PF04386.8_SspB_seed 137 213 !Q:1,1|22,22|28,30|33,34|46,48|50,51|70,70|76,76|80,81|113,113|117,212 Q:0,0|2,21|23,27|31,32|35,45|49,49|52,69|71,75|77,79|82,112|114,116 S?HHHHHHHHHHHHHHHHHHHH-HHHSS-??TT??EEEEEESSSTT--?B??HHHHHHSSSEEEEEESSS?EEEEE?SSE--EEEEEEETTEEEEEEEEGGGEEEEEEGGGTE-EEE?????????????------------------------------------------????????--------????????????????-???????? 1OU8|A PF04388.7_Hamartin_seed 6 935 !Q:19,25|35,37|47,60|64,64|66,67|99,99|121,123|162,162|169,171|173,174|177,181|184,211|217,217|240,240|250,253|255,257|265,291|301,302|308,309|316,316|337,934 Q:0,18|26,34|38,46|61,63|65,65|68,98|100,120|124,161|163,168|172,172|175,176|182,183|212,216|218,239|241,249|254,254|258,264|292,300|303,307|310,315|317,336 HHHHHHHHHHHHHHHHTTS???????HHHHHHHHH---HHHHHHHHH--------------HHH?H--HHHHHHHHHHHTSGGGHHHHHHHHHHHHHTT?TTGGGGGGGTHHHHHHHHHHH???HHHHHHHHHHHHHHHTTTSSTTTTTHHHHHHHHHHHHT?BTTTBS???S??SS?????SS????????????????????????????GGGTT?SHHHHHHHHHHHSHHHHHHHTT?HHHHHHTTT????S???HHHHHHH---------------------------HHHHHTTBB??GGGGT??HHHHHS?TTHHHHHHHHHHHHHHHHTB------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?-------------------------------?------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 4KK0|A PF04389.12_Peptidase_M28_seed 65 343 !Q:8,23|27,34|43,45|57,59|61,61|72,89|98,99|101,101|105,111|117,117|120,121|134,168|179,179|181,187|190,195|198,199|203,204|219,237|245,262|271,274|282,283|287,288|291,293|296,297|300,319|323,323|333,336|341,341 Q:0,7|24,26|35,42|46,56|60,60|62,71|90,97|100,100|102,104|112,116|118,119|122,133|169,178|180,180|188,189|196,197|200,202|205,218|238,244|263,270|275,281|284,286|289,290|294,295|298,299|320,322|324,332|337,340|342,342 EEEEEEEE???------??----?TTS----????TTTTHHHH---HHHHHHHHHTH---H-HHGGGGTSSE------------------EEEEEEES??S?SSS------?BTTBS?HH--HHHHHHHHHHTT----------------------------------?STTEEEEEEE?S---?---SS------SS??EEE??GGGHHHHHHHHHHH-------------------HHHHHTT??????????????????EEEEEETT????STTHHHH--TTT??EE---EE??SS------------------??TTT-TSTTSSGGG--??HHHH-H 2ZEF|A PF04390.7_LptE_seed 162 243 !Q:0,51|59,65|68,69|85,85|88,88|91,91|94,105|107,107|115,115|125,128|132,137|140,141|156,159|163,168|172,177|181,183|190,200|203,205|208,213|222,223 Q:52,58|66,67|70,84|86,87|89,90|92,93|106,106|108,114|116,124|129,131|138,139|142,155|160,162|169,171|178,180|184,189|201,202|206,207|214,221|224,242 --------?--------????????-??-------------------?????EEEEEES------?TT--SHHHHHHHHHHHHTT?EE?SS?SS------------S?EEEEEEE-EEEEEEEEE?---TTS------SE--EEEEEEEEEEEEEE---?TTS?----?EEE------EEE---EEEEEE--??-------SS?--HH------HHHHHHHH--HHHHHHHHHHHHHHHHHHH 2R76|A PF04392.7_ABC_sub_bind_seed 9 303 !Q:7,9|28,29|41,41|44,44|59,60|78,78|81,82|84,84|92,92|99,99|101,101|105,106|114,119|134,135|142,142|145,145|164,164|171,171|188,188|194,194|196,196|206,207|217,218|231,231|233,233|238,239|258,259|264,265|268,274|279,279|288,291|298,298|301,302 Q:0,6|10,27|30,40|42,43|45,58|61,77|79,80|83,83|85,91|93,98|100,100|102,104|107,113|120,133|136,141|143,144|146,163|165,170|172,187|189,193|195,195|197,205|208,216|219,230|232,232|234,237|240,257|260,263|266,267|275,278|280,287|292,297|299,300 EEEEEES???HHHHHHHHHHHHHHHHTT??BTTTEEEEEEE?TT?HHHHHHHHHHHHTT??SEEEEESHHHHHHHHHH?SS--S?EEEEEES?TTTTTS?S?SSS??SSEEEEE--????HHHHHHHHHHHSTT??EEEEEE?TT?HHHHHHHHHHHHHHHHTT?EEEEEE?SSGGGHHHHHHHHHTT?SEEEE?S?HHHHHTHHH--HHHHHHHTT??EEESSHHHHHTT?S-EEEE??HHHHHHHHHHHHHHHHTT??GGGS??EE???---?EEEE?HHHHHHTT????HHHHHH?SB?? 3LFT|A PF04397.10_LytTR_seed 114 120 !Q:14,15|18,18|29,33|35,35|40,40|43,43|52,52|54,54|76,81|85,86|88,89|96,100|102,102|107,107 Q:0,13|16,17|19,28|34,34|36,39|41,42|44,51|53,53|55,75|82,84|87,87|90,95|101,101|103,106|108,119 SSEEEEEGGGEEEE--EE-ETTEEEEEES-----S?EEEE-SS?HHHHHHHS?T-TTEEEEETTEEEEGGGEEEEE?----?SSS-?E--EEEETT-----S?EEEE?TTTHHHHHHHHT 4G4K|A PF04398.7_DUF538_seed 58 204 !Q:1,1|10,10|13,13|20,22|27,27|31,31|35,35|38,38|40,45|47,58|66,70|77,86|91,117|121,121|124,140|147,147|151,157|164,166|170,174|180,180|183,184|188,192|194,196|203,203 Q:0,0|2,9|11,12|14,19|23,26|28,30|32,34|36,37|39,39|46,46|59,65|71,76|87,90|118,120|122,123|141,146|148,150|158,163|167,169|175,179|181,182|185,187|193,193|197,202 S?HHHHHHHS?TT?TTTSSS-?-EEEE?TTT?SEE-EE?S------S---------?--EEEESTT-----SSEEEE---------?SEEE---------------------------EEE?SS----------------?EEEEES?EEE-------SSSEES???BEE----?SSSEE?TT--SSS-----S???HHHHSS? 1YDU|A PF04399.8_Glutaredoxin2_C_seed 23 136 !Q:26,26|30,30|46,46|48,48|75,75|77,77|81,81|85,85|87,88|108,110|126,128|130,130|134,135 Q:0,25|27,29|31,45|47,47|49,74|76,76|78,80|82,84|86,86|89,107|111,125|129,129|131,133 HHHHHHHHHHHHHHHHHHHHHHHHTT?GGG?SHHHHHHHHTTTTTT?T-HHHHHHHHHHHHHHHHHHHHHHHHHH?S-SSS?TTS-S??HHHHHHHHHHHHHHTSTTS???HHHHHHHHHHHHHHT???S-GGG?? 1G7O|A PF04402.9_SIMPL_seed 156 402 !Q:11,13|24,25|34,40|44,44|46,47|59,64|66,68|72,83|85,87|90,90|93,107|110,110|112,124|128,133|135,137|140,141|143,175|177,177|182,182|184,193|199,199|202,203|207,208|211,214|220,225|233,235|238,264|267,268|270,270|272,273|278,279|302,305|307,309|317,330|333,333|336,351|354,355|367,373|377,380|383,383|391,395 Q:0,10|14,23|26,33|41,43|45,45|48,58|65,65|69,71|84,84|88,89|91,92|108,109|111,111|125,127|134,134|138,139|142,142|176,176|178,181|183,183|194,198|200,201|204,206|209,210|215,219|226,232|236,237|265,266|269,269|271,271|274,277|280,301|306,306|310,316|331,332|334,335|352,353|356,366|374,376|381,382|384,390|396,401 EEEEEEEEEEE???BEEEEEEEEE--EESSHHHH-------HHH-H--HHHHHHHHHHH------H---HHT-------??---T---TS-EE-----?------???EE-E-------------EEE------E???TT??S--------------------------------?S?EEEE-E----------EEEEE-EE--EEE?-SG----GGHHH------HHHHHHH---TS?----------------?--??----?TT??B?S??HHHH--HHHHHHHHHHHHHHHHHHHHHT----T-??EEEEEEE--------------EE?SS???------------?EE??GGGHHHHHTTS------?TTS????TT?EEEEEEE-----EEEEEE 4HVZ|A PF04406.9_TP6A_N_seed 65 105 !Q:0,6|10,14|26,26|34,35|37,37|51,62|65,67|70,77|91,91|95,97 Q:7,9|15,25|27,33|36,36|38,50|63,64|68,69|78,90|92,94|98,104 ???---?HHH-----HHHHHHHHHHH-HHHHHTT??E-EHHHHHHHGGGSG------------GG??-SS--------HHHHHHHHHHHHH-HHT?-?GGGGTEE 2ZBK|A PF04408.18_HA2_seed 140 245 !Q:12,22|24,27|30,47|49,50|60,61|63,63|71,72|74,74|81,90|104,104|106,107|109,141|150,206|208,209|215,225|230,238|245,245 Q:0,11|23,23|28,29|48,48|51,59|62,62|64,70|73,73|75,80|91,103|105,105|108,108|142,149|207,207|210,214|226,229|239,244 HHHHHHHHHTSB----------?T----TS-----------------?B?-HHHHHHTTS?-S?HHHHHHH--H-HHHHTT?---------HHHHHHHHHHHTS-S??B??------------------------------?GGGHHHHH---------------------------------------------------------H--HHHTT----------?BTTB---------HHHHHH- 2XAU|A PF04410.9_Gar1_seed 57 185 !Q:0,23|39,42|48,49|51,57|61,61|64,64|68,69|72,73|76,76|89,89|95,101|103,103|106,107|110,111|113,114|117,117|128,128|132,132|134,184 Q:24,38|43,47|50,50|58,60|62,63|65,67|70,71|74,75|77,88|90,94|102,102|104,105|108,109|112,112|115,116|118,127|129,131|133,133 ???????????---?????--???SEEEEEEEEEEETTE----EEEEE??S-------SEE?TT?EEE-?TT??EE-EEEEEEESBSSS?EEEEE-------E?TT??TT--S??TT?EEEEETTSEE?GGG-G?-----------------------?-------------------------- 2EQN|A PF04413.11_Glycos_transf_N_seed 154 248 !Q:0,7|11,13|17,18|26,45|47,47|52,53|72,77|80,80|87,87|95,96|100,109|112,114|116,116|122,125|139,145|153,156|163,167|169,169|176,191|193,194|203,205|212,212|224,227|229,231|235,237|241,247 Q:8,10|14,16|19,25|46,46|48,51|54,71|78,79|81,86|88,94|97,99|110,111|115,115|117,121|126,138|146,152|157,162|168,168|170,175|192,192|195,202|206,211|213,223|228,228|232,234|238,240 ???----?HHH---HHS??GGGGGGT--------------------T?EEEE-?SSHHHHHHHHHHHHHHHH------HS?EEEEES?GGGHHHH--HTT----------GG---G?SEEEE??-?SSHHHHHHHHHHH??-----SEEEEES????HHHHHH??---S?EEEEEE---------????-?-H--HHHHHHTT?--SEEEES?HHHHHHHHTTT??--S---EEE???GGG?-??--? 2XCI|A PF04414.7_tRNA_deacylase_seed 34 275 !Q:2,2|9,10|15,17|28,28|31,33|39,40|42,42|45,52|57,57|60,60|62,63|65,65|82,86|88,89|91,92|95,95|100,101|103,103|106,110|112,112|127,127|144,165|172,172|174,174|177,177|196,196|202,212|214,225|237,238|240,240|243,243|247,247|251,252|266,266|269,269 Q:0,1|3,8|11,14|18,27|29,30|34,38|41,41|43,44|53,56|58,59|61,61|64,64|66,81|87,87|90,90|93,94|96,99|102,102|104,105|111,111|113,126|128,143|166,171|173,173|175,176|178,195|197,201|213,213|226,236|239,239|241,242|244,246|248,250|253,265|267,268|270,274 GG?TTHHHH--HTTT???SEEEEEEEEE?TT???EEEEE??B?SS-----?-?TTSS?TT?B??B?HHHHHHHHHHHHTTGG-----G--S--TT?EEEE??S?SS?????S?EEEEEEEESHHHHT?HHHHHHHHHHHHHHHH??????----------------EEEEEE?S?TT?HHHHHHHHHBSEEEEEEE?GGGGG-----------G-??---------HHHHHHHHHHH--T?SE-EEE?TTT??HHHHHHHHHHHHH-HT?EEEEH 1YQE|A PF04419.9_4F5_seed 40 45 !Q:0,2|14,16|19,27|30,30|33,33|36,39|42,45 Q:3,13|17,18|28,29|31,32|34,35|40,41 ???SGGGTTTSTTT???SS---------SS?SS?SS????TT?-?- 1WVK|A PF04420.9_CHD5_seed 27 199 !Q:0,40|63,63|67,67|102,198 Q:41,62|64,66|68,101 ?------------???--??????????????-------??HHHHHHHHHHHHHHHHHHHTTS?TTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?????-------------------------???????------------------------------------------------------------ 3B2E|E PF04421.8_Mss4_seed 5 116 !Q:3,3|6,6|10,11|15,15|19,19|23,25|30,30|32,47|52,53|59,59|61,65|68,68|75,76|79,79|86,86|90,94|104,104|115,115 Q:0,2|4,5|7,9|12,14|16,18|20,22|26,29|31,31|48,51|54,58|60,60|66,67|69,74|77,78|80,85|87,89|95,103|105,114 BSS?EE?TTT??EEE?TTS?EEE???EEEE?S?---????????????EEEE??EEEES?G-----GG?SSEEEE??BT-TEEEEE?TTT?????EEEETTSTT?EEEEGGGSEE? 2FU5|A PF04423.9_Rad50_zn_hook_seed 32 57 !Q:18,18|21,22|24,24|28,29|32,32|37,37 Q:0,17|19,20|23,23|25,27|30,31|33,36|38,56 HHHHHHHHHHHHHHHHTT?SE--E?TTT??EE?HHHH-HHHHHHHHHHHHHHHHHHH 1L8D|A PF04427.13_Brix_seed 149 509 !Q:1,2|6,21|23,25|27,28|43,44|49,56|58,60|63,71|74,79|90,93|101,102|108,108|118,124|128,129|137,148|150,155|158,160|163,163|169,177|179,194|206,224|237,238|240,240|243,244|248,258|270,300|304,334|340,340|342,481|490,490|494,495|498,504|507,508 Q:0,0|3,5|22,22|26,26|29,42|45,48|57,57|61,62|72,73|80,89|94,100|103,107|109,117|125,127|130,136|149,149|156,157|161,162|164,168|178,178|195,205|225,236|239,239|241,242|245,247|259,269|301,303|335,339|341,341|482,489|491,493|496,497|505,506 E--EES----------------S---S??HHHHHHHHHHHTTS--TTEE--------E???TT------?-?HH------HHHHHHHHTT----EEEEEEE--EEETT-EEEEEEEEE?-----?SSS??EEEEEEE------------E------EE---EE?HHHHT???????--S?--------------?EEEEEESSSST-------------------HHHHHHHHHHHH??B-SS??SSS?----------EEEEEEEEEET-------------------------------TEE-------------------------------EEEEE?S--------------------------------------------------------------------------------------------------------------------------------------------SSEEEEEE-EEE??SS-------SB?? 2CXH|A PF04430.9_DUF498_seed 101 159 !Q:4,5|13,13|15,18|22,31|44,45|49,66|71,80|91,91|95,95|102,102|106,112|120,120|125,127|133,133|149,152|158,158 Q:0,3|6,12|14,14|19,21|32,43|46,48|67,70|81,90|92,94|96,101|103,105|113,119|121,124|128,132|134,148|153,157 EEEE--ETTEEEE-T----TEE----------EESEEEEETTEE--EEE--?--------------?SSSS?-?-------TGGGHHHHHT-GGG?SEEEEE?TTS--?????HHHHHHH-HHTT--?EEEEE?HHHHHHHHHHHHHTT--??EEEEE? 2FVT|A PF04433.12_SWIRM_seed 79 143 !Q:0,9|12,13|16,19|23,24|28,28|32,33|35,55|57,64|68,68|71,73|87,88|91,91|95,97|102,111|116,119|121,123 Q:10,11|14,15|20,22|25,27|29,31|34,34|56,56|65,67|69,70|74,86|89,90|92,94|98,101|112,115|120,120|124,142 ???????---TT??TT-???HHH--HHH?GGG??S---------------------S-?------TTS?HH---HHHHHHHHHHHHH--HH?TTS???HHHH----------HHHS?---S--?HHHHHHHHHHHHHTTSSSS 2V1D|A PF04437.8_RINT1_TIP1_seed 19 640 !Q:18,21|23,25|29,29|45,47|56,56|59,65|70,70|95,113|117,117|140,142|144,162|168,169|190,217|227,227|251,253|256,257|284,286|288,298|335,358|370,385|387,387|426,428|433,451|453,453|473,475|503,504|506,506|518,518|526,537|540,542|560,560|564,565|576,599|601,603|611,612|614,614|618,618|620,628 Q:0,17|22,22|26,28|30,44|48,55|57,58|66,69|71,94|114,116|118,139|143,143|163,167|170,189|218,226|228,250|254,255|258,283|287,287|299,334|359,369|386,386|388,425|429,432|452,452|454,472|476,502|505,505|507,517|519,525|538,539|543,559|561,563|566,575|600,600|604,610|613,613|615,617|619,619|629,639 HHHHHHHHHHHHHHHHHT?---S???HHH-HHHHHHHHHHHHHHH---HHHHHHHH?BG-------GGTB?HHHHHHHHHHHHSHHHHHHHHHHH-------------------HTS?HHHHHHHHHHHHHHHHHHHHHT???S-----------------??GGGGS-?HHHHHHHHHHHHHHHHHHHH----------------------------HTTSSGGGG-GGHHHHHHHHHHHHHHHHSHHHH???GG--GGHHHHHHHHHHHHHHHHHHHHHHHT???S----------?SEEEHHHHHHHHHHHHHHHHHHHHHHHHHTTSHHHH------------------------HHHHHHHHHTT-------------???S?TTHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHTHHHHH-??GGGT????---????????????G-GGHHHHHHHHHHHHHHHTS???HHHHHHHHHHHHHHHHHHHHHTTTTTS-?B?HHHHHHHHHHH-HHHHTTS??---------?TT???HHHHHHHHHHHHHGGGG?GGG--TTTTSHHHHH------------------------H???SHHHHHH--T?SSS?H---------HHHHHHHHHHH 3FHN|A PF04438.11_zf-HIT_seed 100 44 !Q:0,1|5,5|7,8|10,10|13,14|18,18|21,21|25,26|28,35 Q:2,4|6,6|9,9|11,12|15,17|19,20|22,24|27,27|36,43 ??EEE?S--S?TT??EEE?EE?TTT??E--------ESSHHHHH 2YQP|A PF04439.7_Adenyl_transf_seed 6 294 !Q:0,2|17,17|26,41|50,50|57,57|65,66|72,72|76,76|79,81|83,85|89,89|100,100|118,130|137,138|140,146|153,156|182,182|198,198|212,213|217,218|229,229|240,242|272,276|280,280|293,293 Q:3,16|18,25|42,49|51,56|58,64|67,71|73,75|77,78|82,82|86,88|90,99|101,117|131,136|139,139|147,152|157,181|183,197|199,211|214,216|219,228|230,239|243,271|277,279|281,292 ???HHHHHHHHHHHHHH?TTEEEEEE????????????????EEEEEEES?HHHHHT?SGGGGGG??EEEEE?TTS?SS---S???STT?EEEEEEETTS?EEEEEEEEGGGHHHHHH------???????EEEESS??S???????GGGTEE????HHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHTHHHH-HHHHHHHHHHHHH??EEE??GGGTTGGGTS?HHHHHHHHTT???SSHHHHHHHHHHHHHHHHHHHHHHHHHHT????-SHH-HHHHHHHHHHHH? 2PBE|A PF04442.9_CtaG_Cox11_seed 135 175 !Q:0,38|42,54|56,59|69,69|73,73|78,78|80,80|86,86|89,92|100,100|104,104|107,109|114,114|118,118|126,127|130,130|132,133|136,136|139,139|146,148|150,150|162,163|165,166|172,172|174,174 Q:39,41|55,55|60,68|70,72|74,77|79,79|81,85|87,88|93,99|101,103|105,106|110,113|115,117|119,125|128,129|131,131|134,135|137,138|140,145|149,149|151,161|164,164|167,171|173,173 ???-???????-??????????------------??-??SSS?-----------?S--??EEEEEEEEE?TTS?EEEE?S?SEEEE?TT????EEEEEEE?SSS?EE???EEEE?SSS?STTBTTS??SS?S??EE?TT?EEEEEE???B?GGGGSSTTTTT??B??EEEEE?S? 1SO9|A PF04444.9_Dioxygenase_N_seed 19 83 !Q:0,0|23,24|41,45|48,48|74,74|76,80 Q:1,22|25,40|46,47|49,73|75,75|81,82 ?HHHHHHHHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHHH-----TT?HHHHHHHTTHHHHHHHHHHHHHHHT-T???--SS 3HKP|A PF04445.8_SAM_MT_seed 7 248 !Q:11,11|14,14|17,17|24,24|27,32|40,40|44,45|47,49|63,63|75,75|80,82|88,88|102,103|109,110|127,127|144,144|151,155|157,157|160,161|167,177|182,182|194,196|210,210|222,224|228,230|232,232|236,236|246,247 Q:0,10|12,13|15,16|18,23|25,26|33,39|41,43|46,46|50,62|64,74|76,79|83,87|89,101|104,108|111,126|128,143|145,150|156,156|158,159|162,166|178,181|183,193|197,209|211,221|225,227|231,231|233,235|237,245 SHHHHHHHHHT?EE?TT?SEEEEE?SS-----?EEEEETT?GGG??B???SSSHHHHHHHHHS?GGGSHHHHHTT?BTTB???EEETT?TTSHHHHHHHHHT??EEEEE??HHHHHHHHHHHHHHHH?SSSHHHHHHHEEEEES?TTTSST-----T?SS??SEEEE??????---??TTTT?SHHHHHHHHHH???TTGGGGHHHHHHH?SSEEEEEEETT???GGG???S?EEE?SSEEEEEEE?? 2R6Z|A PF04446.7_Thg1_seed 100 195 !Q:5,5|9,12|14,18|39,39|42,43|46,50|65,65|71,71|88,88|90,91|93,94|96,109|137,137|140,144|146,149|151,185|195,195 Q:0,4|6,8|13,13|19,38|40,41|44,45|51,64|66,70|72,87|89,89|92,92|95,95|110,136|138,139|145,145|150,150|186,194 SSGGG-GGG????B---??TTSEEEEEEEETTHHHHHHH-TT??SS---??HHHHHHHHHHHHHH-HHHSS-SEEEEEEETTEEEEEE?T--T??T--------------TTTBHHHHHHHHHHHHHHHHHHTHHHH?SS-----S-???S------------------------------?--??EEEEEEEES- 3OTD|A PF04449.7_Fimbrial_CS1_seed 13 154 !Q:11,13|22,22|24,25|30,31|40,41|52,52|56,56|64,66|76,76|90,91|94,94|96,98|101,101|107,108|111,112|114,114|116,118|126,127|129,129|133,138 Q:0,10|14,21|23,23|26,29|32,39|42,51|53,55|57,63|67,75|77,89|92,93|95,95|99,100|102,106|109,110|113,113|115,115|119,125|128,128|130,132|139,153 EEEEEEEEEEE???EEEEETTS?B??SEEE??EETTTTEE??EEEEEEEEES?TTS?EEEEESS??-EEEETTEEE-EEEEEEEEETTEE??SS?E---EE?GGGGT??TT??S?B???EEEEEEE??S-STT????--SEEEEEEEEEEEEET 4HJI|A PF04451.7_Capsid_NCLDV_seed 37 423 !Q:1,4|8,9|18,18|29,29|44,50|54,55|62,67|79,118|124,125|127,129|133,136|147,148|151,152|156,160|164,268|283,284|289,289|297,297|302,302|304,307|309,331|341,341|348,351|357,357|359,359|367,367|372,372|375,379|386,387|398,399|401,402 Q:0,0|5,7|10,17|19,28|30,43|51,53|56,61|68,78|119,123|126,126|130,132|137,146|149,150|153,155|161,163|269,282|285,288|290,296|298,301|303,303|308,308|332,340|342,347|352,356|358,358|360,366|368,371|373,374|380,385|388,397|400,400|403,422 T????EEE--EEEEEEEE?HHHHHHHHHS?EEEEEEEEEEEEEE????--?SSS??EEEEEE?---??SEEEEEEEEEE---------------------------------------?TTSTT??S???SST----TSSTTTTSTT??SS??GGG?????GGG-------------------------------------------------------------------------------------------------------??EEEEEEEESSSBSS??EEHH-HHHTHHH-HHHT?S?-??T-----------------------TEEEEESSS-STTSSS????EEGGG?S?EEEEEEE?EEEE?TT----?HHHHSS??TTEEEGGGGG??E--EEEEEEEEEEEEEETTEEEE 3KK5|A PF04452.9_Methyltrans_RNA_seed 96 268 !Q:5,5|16,18|21,21|27,28|32,32|42,42|47,47|53,60|63,69|73,77|84,85|88,88|103,104|110,111|114,127|144,144|147,148|151,153|155,156|162,162|171,177|182,193|202,203|205,213|215,215|222,223|226,228|238,238|241,241|245,247|250,253 Q:0,4|6,15|19,20|22,26|29,31|33,41|43,46|48,52|61,62|70,72|78,83|86,87|89,102|105,109|112,113|128,143|145,146|149,150|154,154|157,161|163,170|178,181|194,201|204,204|214,214|216,221|224,225|229,237|239,240|242,244|248,249|254,267 EEEES-HHHHHHHTTT???TT?EEEEE?-TTS?EEEEEEEEE?SSEE-EEEEE--------EE???????SSE-----EEEEEE??ST-THHHHHHHHHHHTT??EEEEE??TT?????-????????HHHHHHHHHHHHHHTT?SS??EE???B-?HHHHH-HHGGGSSE-------EEEE???????-????HHHHHHHT??T---------T?EEEEEE??TT???HHHHHHHHH-TT?EEE???SS-???TTTHHHHHHHHHHH 4E8B|A PF04454.7_Linocin_M18_seed 59 279 !Q:0,2|5,5|11,12|20,21|33,33|43,46|49,50|60,62|65,65|67,78|80,81|89,89|110,110|113,115|136,137|142,144|148,149|155,159|180,184|186,187|189,189|209,210|214,214|226,226|234,234|237,238|256,256|265,265 Q:3,4|6,10|13,19|22,32|34,42|47,48|51,59|63,64|66,66|79,79|82,88|90,109|111,112|116,135|138,141|145,147|150,154|160,179|185,185|188,188|190,208|211,213|215,225|227,233|235,236|239,255|257,264|266,278 ??-SS?GGGSS??HHHHHHH--HHHHHHHHHHH?GGGGTSEEE????TT??EEEEEEEEE???TT?S------------S??EEEEEEE?EEEEEEEEEEHHHHHHHHHT?SS???HHHHHHHHHHHHHHHHHHHT??TTTT???STT?-GGGEE???--SSHHHHHHHHHHHHHHHHTT-----T??S-SEEEEEEHHHHHHHHHHSS--SSS?HHHHHHHHTTS?EEEEESS?SS--EEEEETTSSSEEEEESS?SEEEEEEE?SSEEEEEEEEEEE 2E0Z|A PF04455.7_Saccharop_dh_N_seed 35 112 !Q:0,0|3,3|6,7|13,14|32,32|41,42|48,48|77,78|81,83|90,91|95,96|98,99|101,111 Q:1,2|4,5|8,12|15,31|33,40|43,47|49,76|79,80|84,89|92,94|97,97|100,100 ?EE-EE--EEEEE??TTSSHHHHHHHHHHHTT?EEEEEEEE??SSTTS?EEEEEEEEESSHHHHHHHHHHHHHHHHH-?TT---EEEEEE??SSS??B??S???--?????? 3MGJ|A PF04456.7_DUF503_seed 79 97 !Q:4,4|11,15|38,38|45,45|48,48|62,62|77,79|81,81|85,86|97,97 Q:0,3|5,10|16,37|39,44|46,47|49,61|63,76|80,80|82,84|87,96 EEEE-EEEEEE?-?-?SSHHHHHHHHHHHHHHHHHHSS?EEEEEE?TT?SSEEEEEEEEEES?HHHHHHHHHHHHHH---H-HHS?-SSEEEEEEEE- 1J27|A PF04461.8_DUF520_seed 108 174 !Q:0,1|7,10|34,36|54,54|74,76|82,84|87,87|101,102|104,105|121,121|123,123|139,139|152,152|155,158|160,164|166,167 Q:2,6|11,33|37,53|55,73|77,81|85,86|88,100|103,103|106,120|122,122|124,138|140,151|153,154|159,159|165,165|168,173 ??EEEEE????HHHHHHHHHHHHHHHTTBGGGTT??-EEEEEETTTTEEEEEES?HHHHHHHHHHHHHHHHHTT??-GGGEE??-SS?EEETTEEEEEEEE??S??HHHHHHHHHHHHHHT?S-EEEEEETTEEEEEES?HHHHHHHHHHHH-HS--??S-----S??EEEEEE 1IN0|A PF04464.9_Glyphos_transf_seed 22 457 !Q:6,7|10,10|12,12|28,28|37,37|41,42|45,45|60,71|74,74|98,105|107,109|111,112|115,117|120,120|125,126|129,131|134,135|139,139|141,144|147,148|159,162|167,167|169,171|186,189|193,197|200,200|206,207|219,219|232,233|236,236|238,239|244,248|252,270|276,279|282,282|288,291|303,305|312,322|325,325|332,332|335,335|337,343|351,351|359,359|369,371|376,376|383,385|389,390|395,396|404,404|440,440|442,443|445,445 Q:0,5|8,9|11,11|13,27|29,36|38,40|43,44|46,59|72,73|75,97|106,106|110,110|113,114|118,119|121,124|127,128|132,133|136,138|140,140|145,146|149,158|163,166|168,168|172,185|190,192|198,199|201,205|208,218|220,231|234,235|237,237|240,243|249,251|271,275|280,281|283,287|292,302|306,311|323,324|326,331|333,334|336,336|344,350|352,358|360,368|372,375|377,382|386,388|391,394|397,403|405,439|441,441|444,444|446,456 HHHHHH??GG-G?EEEEEEEEBGGGTBS?HHHHHHHH-HHH--HH?TTSEEEEEESSGGG--------????SS?EEEETTSHHHHHHHHHEEEEEES--------S???T--TS???TT?EEEE??SS?-?SB??GGG?S????TT??HHHHHHHHHH----HHTT?S---EEEESSHHHHHHHH----HHT?--??GG-GEEES??GGGHHHHHSTT?HHHHHHHHHHTT??SS?E--EEEE?????GGG??-----------------GGGSS????TT?HHHHH----HHHTTTEEEEE???HHHHTT???--------TT?TTTEEE?TT?S------?HHHHHHT?SEEEESS?THHHHHGGG???EEEE?TTTTTT---TSS??SBSS?-TTSSSSS?EESSHHHHHHHHTTHHHHHHHTHHHHHHHHHHHST-T??S?HHHHHHHHHHH 3L7J|A PF04466.8_Terminase_3_seed 10 495 !Q:0,1|9,9|27,30|34,38|43,43|47,48|68,68|82,82|86,88|90,91|100,100|107,115|120,120|125,126|130,130|138,145|149,149|156,159|173,193|202,202|206,206|208,209|211,212|225,228|230,230|240,242|244,246|251,254|256,256|272,275|277,277|284,286|290,291|302,302|310,310|312,313|330,330|337,337|344,345|357,358|364,364|368,369|376,392|423,427|431,432|435,435|440,440|454,454|457,459|463,463|465,466|468,469|478,482|493,495 Q:2,8|10,26|31,33|39,42|44,46|49,67|69,81|83,85|89,89|92,99|101,106|116,119|121,124|127,129|131,137|146,148|150,155|160,172|194,201|203,205|207,207|210,210|213,224|229,229|231,239|243,243|247,250|255,255|257,271|276,276|278,283|287,289|292,301|303,309|311,311|314,329|331,336|338,343|346,356|359,363|365,367|370,375|393,422|428,430|433,434|436,439|441,453|455,456|460,462|464,464|467,467|470,477|483,492 ??SEEEEEE?TTSSHHHHHHHHHHHHH----TTS---??EEEE-EES??SSGGGSTHHHHHHHHHHHT?GGGEEEETTEEEE-TTT?-?E--EEEEETTT?HHHHHH??----???EEEE?SGGG??HHH-HHHHGGG??------STT?EEEEEE?-??BTTSHHHHHHTTS--------??-----------SSEEEEEE?GGG?T--T??HHHHHHHHHHHH----H?HHHHHHHTS???B???TTBS----S?HHHHHHHBTHHHHHT????S?EEEEEE???SSS??EEEEEEETTE-EEEEEEE?S??HHHHHHHHHHHHHHTT?SEEEEE?SSTTTT-?HHHHHHHTTTS??EEEEE?TTS??TTTTSB?????????????????BHHHHBSSHHHHHHHHHHHHHHHHHHHHHH?????GGG??EE?HHHH?HHHHHHHHHHHTT?BB???TTS?B-?B??HHHHHHHH?????HHHHHHHHTT??- 4IEE|A PF04471.7_Mrr_cat_seed 227 284 !Q:1,1|3,8|10,12|14,15|34,34|36,37|39,44|49,50|52,57|59,59|61,62|64,64|67,72|74,77|79,81|83,88|90,92|94,94|96,96|98,100|103,103|110,121|124,125|127,128|134,141|143,148|151,152|154,156|158,158|160,160|163,163|167,167|169,169|172,172|174,186|188,188|190,193|195,201|203,208|214,214|216,216|219,221|223,226|230,233|235,236|240,240|242,245|247,248|250,254|256,268|273,275 Q:0,0|2,2|9,9|13,13|16,33|35,35|38,38|45,48|51,51|58,58|60,60|63,63|65,66|73,73|78,78|82,82|89,89|93,93|95,95|97,97|101,102|104,109|122,123|126,126|129,133|142,142|149,150|153,153|157,157|159,159|161,162|164,166|168,168|170,171|173,173|187,187|189,189|194,194|202,202|209,213|215,215|217,218|222,222|227,229|234,234|237,239|241,241|246,246|249,249|255,255|269,272|276,283 H-T------T---S?-HHHHHHHHHHHHHHHHHH-T--T??----EEEE--E------E-S?-S-SS-??---S--??E---E------E---E-E-E---EE?SSSEEE------------EE--E--EEEEE??-----?T------TS--E---E?H-HH-HHH-H-HT-T-?-?---------T-T----E-------E------EEEEE-S-SE---E?---HHH----H--HHH-H----H--T-----T---??--------EEEE--?HHHHHHHH 4F0Q|A PF04472.7_DUF552_seed 120 87 !Q:0,0|5,5|9,9|15,15|18,20|27,29|34,34|38,38|42,44|48,48|62,62|68,70|74,74|80,86 Q:1,4|6,8|10,14|16,17|21,26|30,33|35,37|39,41|45,47|49,61|63,67|71,73|75,79 ?EEEE?SSG-GGHHH-HH---HHHHTT-??EEEE?TTS?HHH---HHH-HHHHHHHHHHHTT?EEEEE---ETT-EEEEE??????? 3P04|A PF04480.7_DUF559_seed 8 111 !Q:0,14|32,33|60,72|84,84|97,97 Q:15,31|34,59|73,83|85,96|98,110 ----???------??HHHHHHHHHHGGGTTTT??EEEEEEETTEEEEEEETTTTEEEEEE???????--????HHHHHHHHHTT?EEEEEEHHHHHH?HHHHHHHHHHHHH 3R3P|A PF04485.7_NblA_seed 14 53 !Q:0,5|22,22|52,52 Q:6,21|23,51 ??????HHHHHHHHHHHTTSSS?TGGGTHHHHTHHHHHHHHHHHHHHHHTTT? 1OJH|A PF04488.10_Gly_transf_sug_seed 22 145 !Q:4,6|12,12|18,18|28,28|30,31|38,38|40,63|73,79|85,95|97,97|113,113|118,118|121,121|124,124|126,126|128,128|134,136|139,140|145,145 Q:0,3|7,11|13,17|19,27|29,29|32,37|39,39|64,72|80,84|96,96|98,112|114,117|119,120|122,123|125,125|127,127|129,133|137,138|141,144 HHHH???HHHHH-HHHHH-HHHHHHHHT?E--EGGGTT?S-----------------------?HHHHHHHHH-------HHHTS??---------H-HHHHHHHHHHHHHHH?EEEE?TT?BS?B?G-GGGGS???TT??HHHH- 2VKH|A PF04490.7_Pox_T4_C_seed 6 157 !Q:1,4|6,7|19,19|28,31|36,36|52,57|66,66|69,69|101,114|127,127|130,130|134,156 Q:0,0|5,5|8,18|20,27|32,35|37,51|58,65|67,68|70,100|115,126|128,129|131,133 S????S??EEEEEEETTTE-EEEEEEES????TTSS?GGGGEEEEEEEESSS?????-EEEEEEEE?SS?EEEEEEETTTEEEEEEEEEEEEHHHHHHTTT???-------????TTSSSHHHHHHT?EE?BSS???????????????????---- 4HKJ|D PF04491.7_Pox_T4_N_seed 5 49 !Q:0,0|12,12|16,22|26,27|48,48 Q:1,11|13,15|23,25|28,47 ?EEEEEEEEEEE-SSS???????EEE??SSSSEEEEEETTEEEEEEES? 4HKJ|D PF04493.9_Endonuclease_5_seed 14 248 !Q:8,15|18,18|20,22|53,54|62,62|66,69|74,74|90,90|93,94|96,118|124,124|132,133|145,145|153,156|158,158|160,166|170,177|179,179|186,190|200,201|207,208|218,218|230,231|234,234|237,237 Q:0,7|16,17|19,19|23,52|55,61|63,65|70,73|75,89|91,92|95,95|119,123|125,131|134,144|146,152|157,157|159,159|167,169|178,178|180,185|191,199|202,206|209,217|219,229|232,233|235,236|238,247 HHHHHHTT????????GG-G?--SEEEEEEEEEEEETTEEEEEEEEEEEETTT??EEEEEEE-EEE????SSSS?GGGGTHHHHHHHHHH?SS??S----------------------?EEEEB?SSSSTTS??HHHHHHHHHTS?EEEEESS????T-T???????SST--------T?EEEEEE-----TTEEEEEEE?-SSTTS??EEEEEEESS?HHHHHHHHHHT??TT?SS?HHHHHHHHHH 2W35|A PF04494.10_TFIID_90kDa_seed 35 153 !Q:0,14|32,32|42,42|54,56|62,63|69,70|88,89|96,97|105,105|115,115|121,121 Q:15,31|33,41|43,53|57,61|64,68|71,87|90,95|98,104|106,114|116,120|122,152 ------?????--??TTHHHHHHHHHHHHHTS?TTTHHHHHH-HHHHHHHHHHH---HHHHH?-HHHHH--HHHHHHGGGGHHHHHHH--HHTTTT??SHHHHHH?HHHHHHHSS?EEEEE?HHHHHHHHHHHHHTGGGTHHHHHHHHHHHEE 2NXP|A PF04495.9_GRASP55_65_seed 37 244 !Q:8,9|16,34|36,36|41,57|61,61|67,68|75,76|83,84|94,96|107,118|121,152|154,154|166,195|214,216|223,225|229,229|234,234|238,238|240,241 Q:0,7|10,15|35,35|37,40|58,60|62,66|69,74|77,82|85,93|97,106|119,120|153,153|155,165|196,213|217,222|226,228|230,233|235,237|239,239|242,243 EEEEETTT??EEEEEE-??---------------?S?SSSS-----------------SSS?EEEEE??HHHHHH??EEEEEE?-TTSHHHHHT-??TTTEEEEEES----------??SS------------------------------??S?HHHHHHHTTTS-----------------------------?EEEEEEETTTTEEEEEEE???TTSSSS---SSS?EEEE?STT?S??SS 4EDJ|A PF04500.11_FLYWCH_seed 128 87 !Q:6,6|11,13|27,32|34,34|36,36|42,42|48,53|55,58|64,69|76,76|78,84 Q:0,5|7,10|14,26|33,33|35,35|37,41|43,47|54,54|59,63|70,75|77,77|85,86 EEEETT-TEEE---EEETTEEEEEEEE?-----S-S?EEEEE-GGGTT------S????EEEEE------TTEEEE?S-?----?SS 2RPR|A PF04507.7_DUF576_seed 29 268 !Q:0,55|57,61|68,73|77,77|80,82|94,94|98,98|125,136|144,144|147,147|153,156|166,168|173,196|201,202|216,220|222,223|228,241|250,250|253,253|265,267 Q:56,56|62,67|74,76|78,79|83,93|95,97|99,124|137,143|145,146|148,152|157,165|169,172|197,200|203,215|221,221|224,227|242,249|251,252|254,264 ????????????????-----?????---------------???????????????S?????GGGGGG??????TTS?SS???EEEEEEEEEEE?TTS?EEEEEEEEEEETTTTEEEEEEEEEEE????????????EEEEEEE?SS?EEESS????HHHHHHHHT???HHHH????????????????????????EEEE??TTSHHHHHHHHHS?????S??EEEE??????????????EEEEEEEE?SS?EEEEEEEEEEE??? 4EG9|A PF04509.7_CheC_seed 33 39 !Q:26,26|28,29|32,34 Q:0,25|27,27|30,31|35,38 HHHHHHHHHHHHHHHHHHHHHHHHHT-S??EE???EEEE 3H4Y|A PF04514.7_BTV_NS2_seed 5 389 !Q:0,10|17,17|20,21|33,33|44,44|52,53|56,56|61,61|81,81|84,84|91,92|96,97|102,102|114,120|132,135|137,137|140,140|144,145|149,152|155,155|158,158|161,161|166,388 Q:11,16|18,19|22,32|34,43|45,51|54,55|57,60|62,80|82,83|85,90|93,95|98,101|103,113|121,131|136,136|138,139|141,143|146,148|153,154|156,157|159,160|162,165 ???--??????EEEEEE?TT??SHHHHHHHHTT?SEEEEEESSS?EEEEESS??TT?EEEE?SSSEEEEEEETTEEEEEEE?SS?EEEESS??TTB??EEEE?EEEEEEEEETT-------EEEEEEEEEEE????S?TT?BSS??GGG????TT?EE?SS?HHHH????????????????????-???--------------------------------------------------------------------------------------------------??-------------------??-----------------???---------------------------------------------------------- 1UTY|A PF04525.7_Tub_2_seed 16 207 !Q:0,1|4,4|9,9|12,12|19,28|37,37|44,47|60,60|64,64|71,84|93,95|97,101|110,122|129,130|132,141|148,148|153,154|159,159|163,164|172,182|184,184|189,189|192,192 Q:2,3|5,8|10,11|13,18|29,36|38,43|48,59|61,63|65,70|85,92|96,96|102,109|123,128|131,131|142,147|149,152|155,158|160,162|165,171|183,183|185,188|190,191|193,206 ??SS?GGGB?SS?EEEEEE??????????EEEEETTS?EEEEEE?---SBTTBTTEEEEE?TTS?EEEEEE?-?-----??????EEEEEETT???G-----GGEEEEEE??---????????EEEEET--T??---?????SEEEES?TTTT??EEEE-GGG??EEEEEEE???-???????B?SEEE-EE?TTSBHHHHHHHHHH 2Q4M|A PF04536.9_TPM_seed 162 312 !Q:0,0|2,4|16,39|43,43|48,65|75,76|79,188|200,200|203,205|208,209|213,213|216,220|227,232|236,237|240,241|243,246|251,251|253,263|270,272|279,279|286,287|295,295 Q:1,1|5,15|40,42|44,47|66,74|77,78|189,199|201,202|206,207|210,212|214,215|221,226|233,235|238,239|242,242|247,250|252,252|264,269|273,278|280,285|288,294|296,311 ?S?--HHHHHHHHHHH------------------------HHH-HHHT??----------------EEEEEEESB?-TT------------------------------------------------------------------------------------------------------------??HHHHHHHHHHH-HS---TT--TTS?TT-----EEEEEE------ETT--TT--E----EEEE-E?----------STTTTT-??HHHHHH-HHHHTH--HHHHHHT?HHHHHHHHHHHHHHHH 3PVH|A PF04539.11_Sigma70_r3_seed 82 78 !Q:19,21|32,32|43,43|46,47|51,52|55,55|59,60|65,65|67,68|71,72 Q:0,18|22,31|33,42|44,45|48,50|53,54|56,58|61,64|66,66|69,70|73,77 HHHHHHHHHHHHHTTSSSS???HHHHHHTSSS?SHHHHHHTTS?SS??BTT??SS?SSS??HHHH?B??SS??HHHHH 4KN4|X PF04542.9_Sigma70_r2_seed 259 101 !Q:5,7|12,14|22,26|30,33|35,36|40,41|54,54|58,59|62,62|65,67|78,81|87,91|96,96 Q:0,4|8,11|15,21|27,29|34,34|37,39|42,53|55,57|60,61|63,64|68,77|82,86|92,95|97,100 HHHHT---HHHH---HHHHTTT----?SSS----S-?HHH--HHHHHHHHHHHH-TTS??SS?SS?--HHHHHHHHHH----HHHHH-----HHTT-TTSS 1SIG|A PF04545.11_Sigma70_r4_seed 130 54 !Q:5,5|22,25|36,36|53,53 Q:0,4|6,21|26,35|37,52 HHHTS?HHHHHHHHHHHTTTTS????HHHHHHHHTS?HHHHHHHHHHHHHHHH? 2H27|A PF04546.8_Sigma70_ner_seed 124 282 !Q:0,0|2,6|22,127|148,154|157,158|161,162|165,166|170,172|187,190|224,226|236,236|238,238|251,252|254,257 Q:1,1|7,21|128,147|155,156|159,160|163,164|167,169|173,186|191,223|227,235|237,237|239,250|253,253|258,281 ?H-----HHHHHHHHHHHHHHT???--?????????????-??????--????--?-????????????-----------------??????????????---------------------???????HHHHHHHHHHHHHHHHHHHH-------HH--HS??ST--TTT---HHHHHHHHHHHHHT????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS???HHHHHHHHT-S?SSSTTTHHHHHT--T?--?TTTSGGGGGHHHHHHHHHHHHHHH 1SIG|A PF04548.11_AIG1_seed 32 255 !Q:7,7|20,24|28,46|48,48|54,54|59,61|69,70|72,76|81,81|83,84|86,87|106,107|112,115|118,119|124,127|142,142|155,155|162,165|173,175|188,188|192,193|196,199|223,224|226,231|233,233|245,245 Q:0,6|8,19|25,27|47,47|49,53|55,58|62,68|71,71|77,80|82,82|85,85|88,105|108,111|116,117|120,123|128,141|143,154|156,161|166,172|176,187|189,191|194,195|200,222|225,225|232,232|234,244|246,254 EEEEEES?TTSSHHHHHHHH-----HTS??-----????????????S?EEEEE-EETT---EEEEEEE??S---?-SSTT-H--H--HHSTTSHHHHHHHHHHTT??SEEE----EE--EETT-???HHHHHHHHHHHHHH?GGGGGGEEEEEE?GGGGTT??--HHHHHHH???HHHHHHHHHTTT?EEE??TT--??HHHHHHHHHHHHHHHHHHHHHTT--T-?????H-HHHHHHHGGGS?HHHHHHHHH 4DCS|A PF04551.9_GcpE_seed 45 846 !Q:0,2|6,7|10,15|23,24|30,34|36,36|39,39|45,48|59,60|66,67|82,87|89,89|91,91|96,97|99,100|108,110|115,115|121,121|126,148|150,151|167,167|178,183|191,191|193,197|199,200|203,205|223,227|234,234|243,243|252,262|266,267|270,271|292,293|297,300|302,304|306,306|310,313|316,711|724,726|729,737|742,745|748,750|752,752|766,767|769,779|781,782|800,800|806,806|808,808|812,814|828,828|831,831|843,846 Q:3,5|8,9|16,22|25,29|35,35|37,38|40,44|49,58|61,65|68,81|88,88|90,90|92,95|98,98|101,107|111,114|116,120|122,125|149,149|152,166|168,177|184,190|192,192|198,198|201,202|206,222|228,233|235,242|244,251|263,265|268,269|272,291|294,296|301,301|305,305|307,309|314,315|712,723|727,728|738,741|746,747|751,751|753,765|768,768|780,780|783,799|801,805|807,807|809,811|815,827|829,830|832,842 ???EEE--TT------EEESTTS??EEEEE??---S?TT?HHHHH----HHHHHHHHTT??EEEEE??SHHHHHHHHHHHHH-----?S-S?EEEE??S?-HHHHHHH---HHTT?SEEEE?HHHH-----------------------S?-HHHHHHHHHHHHHHT?EEEEEEEGGG?----?HHHHHHH-S-----S??HH---HHHHHHHHHHHHHHHTT?--??EEEEEE?SSHHHHHH-HHHHHHHH??-------??EEE??SS??SHHHHHHHHHHHHHHHHHTT??SEE????S---S?HHH----HH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHHHHHHHHTTS-??SS?--------EEEE????TT?-?S?HHHHHHHHHHHTT--T??---------S??EEEEESSSHHHHHHTTT?SEEEE-E?SSE---EEEEETTEEEEEE-ES?HHHHHHHHHHH???- 2Y0F|A PF04552.8_Sigma54_DBD_seed 29 164 !Q:0,83|85,89|92,94|96,97|100,103|108,108|117,119|123,125|138,138|140,142|154,163 Q:84,84|90,91|95,95|98,99|104,107|109,116|120,122|126,137|139,139|143,153 --------------------------------------------------------------------------------????S?????SS-??S??HH----HHHH-HHHHHGGG??-SSS???HHHHHHHHTTTS-S???HHHHHHHHHHT?????????? 2AHQ|A PF04557.10_tRNA_synt_1c_R2_seed 23 104 !Q:0,65|75,80|83,83|85,95 Q:66,74|81,82|84,84|96,103 ??????????????????????????????-----????????--------???????????????TTSSHHHHT---???TT?S---------??SSTTHHHH 3TL4|X PF04558.10_tRNA_synt_1c_R1_seed 27 180 !Q:0,1|14,15|40,41|44,49|62,63|68,74|89,90|108,111|113,114|125,125|127,130|146,146|154,155|170,170|177,177 Q:2,13|16,39|42,43|50,61|64,67|75,88|91,107|112,112|115,124|126,126|131,145|147,153|156,169|171,176|178,179 ??HHHHHHHHHHTT??HHHHHHHTTSHHHHHHHHHHHHTS-?TT--????HHHHHHHHHHHH--HHTT??----?TTHHHHHHHHHTTS??SHHHHHHHHHHHHHHGG----G??HHHHHHTTTT-T????HHHHHHHHHHHHHHT-HHHHHHH--GGGGHHHHHHHHHT?GGGTTS?TT 3TL4|X PF04560.15_RNA_pol_Rpb2_7_seed 134 101 !Q:0,1|4,5|17,17|31,35|46,64|69,78|97,100 Q:2,3|6,16|18,30|36,45|65,68|79,96 ??EE??HHHHHHHHHHT?HHHHHHHHTTTTT----?HHHHHHHHHH-------------------HHTT???????-??HHHHHHHHHHHTSSEEEE???? 1K83|B PF04561.9_RNA_pol_Rpb2_2_seed 22 233 !Q:0,1|3,11|15,32|36,49|53,53|55,61|65,65|67,69|79,80|90,104|107,108|125,126|136,142|146,149|163,177|182,183|186,187|191,192|195,197|214,214|219,222|225,225|229,230|232,232 Q:2,2|12,14|33,35|50,52|54,54|62,64|66,66|70,78|81,89|105,106|109,124|127,135|143,145|150,162|178,181|184,185|188,190|193,194|198,213|215,218|223,224|226,228|231,231 ??S?????????SSS?????????------???SSS??????????????TTS?S???????TTS?S???SHHHHTTTT??STTHHHHHH?--?-----------SS??HHHHHTHHHHHHTTSS??SSHHHHHTT??----?SSS????HHHHHHHHHHHHT---------------TTSS?-SS??SSS??SS---HHHHHHHHHHHHHHHH-TTSS????TT?SSS??B? 1K83|B PF04563.10_RNA_pol_Rpb2_1_seed 21 476 !Q:0,0|3,3|19,31|38,64|71,77|79,81|84,84|86,86|88,91|99,102|112,150|153,155|163,164|175,176|185,186|189,193|195,195|200,200|202,204|206,206|208,211|213,221|225,236|240,253|257,257|259,265|269,269|271,273|283,284|294,295|298,299|302,311|326,327|337,339|343,346|364,364|367,368|372,373|396,399|402,402|406,407|409,410|441,450|452,454|459,459|461,461 Q:1,2|4,18|32,37|65,70|78,78|82,83|85,85|87,87|92,98|103,111|151,152|156,162|165,174|177,184|187,188|194,194|196,199|201,201|205,205|207,207|212,212|222,224|237,239|254,256|258,258|266,268|270,270|274,282|285,293|296,297|300,301|312,325|328,336|340,342|347,363|365,366|369,371|374,395|400,401|403,405|408,408|411,440|451,451|455,458|460,460|462,475 ?TT?SSSSSSSSSTTTTHH-------------HHSSTT?????????????---???????????EEEEEE??-????B?--TT-S?B????TTTTTTT????EEEEEEEEE??????????????---------------??????????SS???EEEEEEE??SSSTTSSSSS??HHHHHHTT??TT?????B?GGGS?B???B?B????S?????????SSS????????????SSS??????????????TTS?S???????TTS?S???SHHHHTTTT??STTHHHHHH??SS??HH----------HHHTHHHHHHTTSS??SSHHHHHTT???SSS????HHHHHHHHHHHHTTTSS?SS??SSS??SSHHHHHHHHHHHHHHHHTTSS????TT?SSS??B??HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??--------S???TTSS?S-TTTSHHHHHHHSSS 1K83|B PF04564.10_U-box_seed 16 80 !Q:0,1|6,6|10,10|13,13|19,19|23,24|38,43|45,45|47,47|51,52|55,56|63,63 Q:2,5|7,9|11,12|14,18|20,22|25,37|44,44|46,46|48,50|53,54|57,62|64,79 ??TTTB?TTT?SB?SSEEE?TTT??EEEHHHHHHHTTT------S?B?TTT-?SB??TTTSEE?HHHHHHHHHHHHHSTT 2QIZ|A PF04565.11_RNA_pol_Rpb2_3_seed 31 72 !Q:1,4|22,22|27,27|31,32|38,39|47,47|50,52|54,54|65,65|68,68|71,71 Q:0,0|5,21|23,26|28,30|33,37|40,46|48,49|53,53|55,64|66,67|69,70 E????SSHHHHHHHHTEEESBS-TTSB?SSS??STTTS??GGGTTTB?SS???S-GGGTTTEEEB?SS?EE? 1K83|B PF04566.8_RNA_pol_Rpb2_4_seed 12 64 !Q:30,30|32,32|34,34|49,50|53,53|63,63 Q:0,29|31,31|33,33|35,48|51,52|54,62 EEETTEEEEEESSTHHHHHHHHHHHHHTSS?T-T?EEEEETTTTEEEEE??TT?EEEEEEEEE? 1K83|B PF04567.12_RNA_pol_Rpb2_5_seed 64 86 !Q:8,9|14,15|22,23|27,27|40,58|61,62|65,69|71,72|74,76|78,78|82,82|84,84 Q:0,7|10,13|16,21|24,26|28,39|59,60|63,64|70,70|73,73|77,77|79,81|83,83|85,85 STTTTTTT--SEEE??TTTGGG??EES?HHHHHHHHHHTT??????-------------SS??SS?????S??S-??S?SEE?S?G 1K83|B PF04568.7_IATP_seed 34 115 !Q:0,42|47,52|57,58|86,114 Q:43,46|53,56|59,85 ------------------------------------------?TTTG------GGSS--HHHHHHHHHHHHHHHHHHHHHHHHHHH????????????????????????????? 1OHH|H PF04574.8_DUF592_seed 14 177 !Q:2,9|13,13|15,22|26,26|28,30|55,55|58,59|75,76|87,126|128,128|150,153|156,157|169,169|171,171 Q:0,1|10,12|14,14|23,25|27,27|31,54|56,57|60,74|77,86|127,127|129,149|154,155|158,168|170,170|172,176 GG??--???-SSS?S????????SSS?S???HHHHHHHHHHHHHHHHHHHHHHHS?SS??TTHHHHHHHHTTEEE??HHHHHHHHHH??----????????????------------??????????S?HHHHHHHHHHHHHHHHHHHTS????TT??SHHHHHHHHHH?S?EEEEE 4IAO|A PF04582.7_Reo_sigmaC_seed 4 326 !Q:0,119|154,154|159,162|175,177|190,191|193,194|209,211|239,239|255,256|258,258|264,265|272,272|306,306|325,325 Q:120,153|155,158|163,174|178,189|192,192|195,208|212,238|240,254|257,257|259,263|266,271|273,305|307,324 --------------------------------------------------------------------------------------------------------------------????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?TTTT????TTEEEETTEEEE???TTTEEESSSEEE??S??EEEEEEEEEEEEES???EEEEEEEEEEETTEEEEEEEEESEEEE?SSEEEEEEEGGGEES??S?GGGGS??HHHHTS?EEEEEEEEETTEEEEEEEEEEEEETTEEEEEEE?SSSSSEEEEEEEEEEEEE? 2BT7|A PF04587.10_ADP_PFK_GK_seed 9 501 !Q:5,6|12,13|19,20|22,23|26,30|40,40|51,52|56,56|73,74|80,82|90,90|94,97|102,105|122,124|128,129|132,133|141,141|143,143|150,157|160,160|164,175|179,180|183,183|186,188|192,193|197,197|200,200|208,208|212,212|216,218|231,231|233,233|240,241|244,245|247,251|254,254|270,271|275,275|281,284|295,296|302,302|308,308|321,321|334,337|353,368|386,386|388,391|414,416|427,429|444,445|450,451|453,462|474,485|495,495 Q:0,4|7,11|14,18|21,21|24,25|31,39|41,50|53,55|57,72|75,79|83,89|91,93|98,101|106,121|125,127|130,131|134,140|142,142|144,149|158,159|161,163|176,178|181,182|184,185|189,191|194,196|198,199|201,207|209,211|213,215|219,230|232,232|234,239|242,243|246,246|252,253|255,269|272,274|276,280|285,294|297,301|303,307|309,320|322,333|338,352|369,385|387,387|392,413|417,426|430,443|446,449|452,452|463,473|486,494|496,500 HGGGS??EEEEE??EEEEE?-B??HH-----HHHHHHHHH?HHHHHHHHHS??SSB?SHHHHHHHHHHHHHHT??EEEEB?-?HHHHHHH-HHH?--?SEEE----EESHHHHHHHHHTTTS???EEE??SS??HHHHHTS?S-SSEEEE????????EE?GGG-?????---???EEE??EE?TT--?EET--TEE?SS?EEEEEEE?SSG-GGT???HHHHHSHHHHHT-T?SEEEEE??TT??T-----TT?HHHHHHHHHHHHHHH--HTT?EEEEE????SSHHHHHHHH--HHGGG?SEEEE?HHHHHHHHHHTT?HHHHHHHHHSSS-?-?HHHHHHHHHHHHHHH?--------------?SEEEEEETTEEEEEESS?S----THHHHHHHHHHHHHHHHHHHSS???GGGGGGGGGS???HHHHHHHHHHHHHS??BTTE--E----------EETTEEEEEEE????????????TTHHHHHHH-HHHHH 1UA4|A PF04588.8_HIG_1_N_seed 59 61 !Q:1,1|3,4|8,11|33,34|36,40|43,45 Q:0,0|2,2|5,7|12,32|35,35|41,42|46,60 S?S??SHH----HHHHHHHHHHHHHHHHHSSSS--S?????SS???SHHHHHHHHHHHHHH 2LON|A PF04591.7_DUF596_seed 19 89 !Q:9,9|15,19|31,32|34,35|39,49|59,61|69,69|71,78|81,82|85,88 Q:0,8|10,14|20,30|33,33|36,38|50,58|62,68|70,70|79,80|83,84 HHTTSEEEE-ETTEE?-???HHHHHHHHHHH??S--SSB???????????BHHHHHHHT--?SSEEEEE?T--------TT??EE--?? 2O5H|A PF04603.7_Mog1_seed 3 147 !Q:13,13|24,26|35,36|38,40|49,50|52,53|75,80|90,96|106,107|115,115|120,121|146,146 Q:0,12|14,23|27,34|37,37|41,48|51,51|54,74|81,89|97,105|108,114|116,119|122,145 EEEEGGGTEEEEE?TTEEEGGGTS???TTEEEEEE??S??-EEEEEEEE??S??SHHHHHHHHHHHHHGGGTEEE------EEEEEEEEE-------ETTTEEEEE--EEEEEET?TTSS??EEEEEEEEEEGGGTEEEEEEEEEE? 1EQ6|A PF04607.12_RelA_SpoT_seed 102 180 !Q:1,4|15,16|19,31|33,35|37,38|44,44|51,52|55,63|76,79|83,83|85,85|88,94|98,110|113,113|115,116|119,122|128,143|145,145|149,149|169,179 Q:0,0|5,14|17,18|32,32|36,36|39,43|45,50|53,54|64,75|80,82|84,84|86,87|95,97|111,112|114,114|117,118|123,127|144,144|146,148|150,168 E????HHHHHHHHHH--HG-------------G---G??TTGGG?EEEEEE--SS---------HHHHHHHHHHHH----HHS?B?TT-----??EET-------------TT-S??TT????EEEEE----------------E?SSS-EEEEEEEEHHHHHHHHHTT??????????? 3L9D|A PF04608.8_PgpA_seed 172 297 !Q:6,6|12,21|35,38|41,41|44,45|54,67|73,73|79,83|99,99|101,101|112,112|115,116|128,198|201,201|204,209|211,211|222,223|231,237|239,255|257,269|272,276|297,297 Q:0,5|7,11|22,34|39,40|42,43|46,53|68,72|74,78|84,98|100,100|102,111|113,114|117,127|199,200|202,203|210,210|212,221|224,230|238,238|256,256|270,271|277,296 HHHHHH-HHHTT--------??HHHHHHHHHHHHT----TT?SS??HHHHHHHH--------------HHHHT?HHHHH-----HHHHHHHHHHHTTTT?S?TTHHHHHHHT?TT??HHHHHHHHHHH-----------------------------------------------------------------------TT?TT------H-HHHHHHHHHH??THHHHHH------?S-----------------S-------------SS--???TTHHHHHHHHHHHHHHHHHH- 1TLQ|A PF04612.7_T2SM_seed 63 188 !Q:0,91|105,110|117,117|120,120|127,128|130,130|146,147|157,175|183,183|186,187 Q:92,104|111,116|118,119|121,126|129,129|131,145|148,156|176,182|184,185 -----------------------------------------------------------???????????????????????---------?HHHHHHHHHHHHT?----?EEEEEE?SS-EEEEEE??B?HHHHHHHHHHHHHHS??EEEEEEEEE??-------------????EEEEEEE-EE?? 1UV7|A PF04613.9_LpxD_seed 90 87 !Q:2,2|9,9|13,14|21,24|26,27|31,31|37,39|45,45|48,52|56,63|65,65|68,68|72,72|74,74 Q:0,1|3,8|10,12|15,20|25,25|28,30|32,36|40,44|46,47|53,55|64,64|66,67|69,71|73,73|75,86 TT?EEEEEE?GGG??TTSEEE??-?G--GGG-GGGGG???SEEEE?HH-----HHT--------T?SS?EEE?S?HHHHHHHHHGGG 3PMO|A PF04614.7_Pex19_seed 27 395 !Q:0,215|253,254|257,257|260,260|282,297|300,301|323,340|346,346|348,348|351,395 Q:216,252|255,256|258,259|261,281|298,299|302,322|341,345|347,347|349,350 -----------------------------------------------?-------------------------------------------------------------------------------------------------------------------------------------------------??????----------???????HHHHHHHHHHHTSHHHHHHHHHHHHTTHHHHHHHHGG--GS?HH-HHHHHHHHHHHHHHHHHHHHH--------------??TT??HHHHHHHHHHHHHHHHHHHHT????--------------GGGTT?S?TT????-------------------------????------------ 2WL8|A PF04616.9_Glyco_hydro_43_seed 37 387 !Q:3,3|6,6|9,10|12,12|21,23|29,30|35,40|43,43|54,54|59,59|62,62|67,71|74,75|78,78|81,86|88,88|92,95|107,107|111,121|125,127|140,142|144,148|151,162|164,164|166,167|172,172|175,177|179,179|188,197|201,201|223,223|228,242|245,247|259,260|267,270|273,273|278,282|287,289|297,300|303,303|306,307|311,311|314,318|321,321|334,334|338,339|348,353|355,357|359,359|363,367|370,370|382,382 Q:0,2|4,5|7,8|11,11|13,20|24,28|31,34|41,42|44,53|55,58|60,61|63,66|72,73|76,77|79,80|87,87|89,91|96,106|108,110|122,124|128,139|143,143|149,150|163,163|165,165|168,171|173,174|178,178|180,187|198,200|202,222|224,227|243,244|248,258|261,266|271,272|274,277|283,286|290,296|301,302|304,305|308,310|312,313|319,320|322,333|335,337|340,347|354,354|358,358|360,362|368,369|371,381|383,386 EES?SB?SS??S?EEEEETTE---EEEEE??BTEE------SB?EEEEESSSSS?EEEE?SB?STTT???--TT??TT?EE-----?S?EEE----EETTEEEEEEE-EES??---------SSS???EEEEEEEESSTT---S?????EE?---------??S?S??EEEE?TT---S?EEEEEEEE???-------TTS?SEEEEEEEEEETTTTEEEEEE-EEEE???------------TT???EEEEEEEETTE--EEEEEE----ES?SSTT----?EEEE---EEESSTT?-??EE?TT??SEE?TT----?TT?SSEEEEEEEEEE?TTS?-EEEEEEEE??????S---S?TTT?????TT?SEEEEEEEEEE-TTEE 1Y7B|A PF04619.7_Adhesin_Dr_seed 6 146 !Q:16,16|19,22|25,27|34,35|38,38|47,48|50,50|55,55|61,61|66,66|69,70|79,80|85,88|96,98|111,111|113,114|125,126|129,130|145,146 Q:0,15|17,18|23,24|28,33|36,37|39,46|49,49|51,54|56,60|62,65|67,68|71,78|81,84|89,95|99,110|112,112|115,124|127,128|131,144 EEEEEEEEEEEEEEEE?SS????SS???EEEGGG??TT?EEEEEEEE??S?TTSE-EEEEE?TTSB?SS?-EEEEETTS??EEEE----EEEESSS?-?EEEETTEEEESS?S??EEEEEEEESS??TT??SEEEEEEEEEEEEE?- 1USZ|A PF04627.8_ATP-synt_Eps_seed 30 67 !Q:0,9|24,57|60,66 Q:10,23|58,59 ??????????HHHHHHHHHHHHTT???????????????-???---------------EE???-??? 2XND|I PF04628.8_Sedlin_N_seed 32 308 !Q:2,2|4,8|11,11|19,20|22,25|32,68|73,75|94,128|130,130|140,143|149,149|154,154|157,158|166,215|217,218|242,269|272,289|291,295 Q:0,1|3,3|9,10|12,18|21,21|26,31|69,72|76,93|129,129|131,139|144,148|150,153|155,156|159,165|216,216|219,241|270,271|290,290|296,307 EE?T-----TS?EEEEEEE??S?--?GGGHHH-------------------------------------HHHH---HHHHHHHHHHHHHHHGGG----------------------------------?S?SEEEEEEEE----TTEEE-EEEE?TT??EEEEEES--------------------------------------------------S??HHHHHHHHHHHHHHHHHHHHSTT?--------------------------?TT?------------???-?H-----HHHHHHHHHHHH 2J3T|D PF04634.7_DUF600_seed 15 151 !Q:15,16|18,18|29,29|32,33|46,47|58,59|61,61|90,91|103,103|110,118|120,120|134,141 Q:0,14|17,17|19,28|30,31|34,45|48,57|60,60|62,89|92,102|104,109|119,119|121,133|142,150 HHHHHHHHHHHHHHH??S?EEEEEEEEEE?TT??EEEEEEEEETTT??EEEGGGGGGT??S?HHHHHHHHHHHHHHHHHHHHHHHHHHSS??SEEEEEEETTS?EEEEEE??----???S?HHHHHHHHHHHHH??????--HHHHHHHHH 2IA1|A PF04644.7_Motilin_ghrelin_seed 6 29 !Q:0,1|4,4|12,12|21,28 Q:2,3|5,11|13,20 ??TT?HHHHHHH-HHHHHHHH-------? 1LBJ|A PF04652.11_DUF605_seed 39 668 !Q:16,17|36,36|38,41|49,52|61,79|86,92|94,101|106,107|133,133|135,139|141,141|161,163|165,190|215,667 Q:0,15|18,35|37,37|42,48|53,60|80,85|93,93|102,105|108,132|134,134|140,140|142,160|164,164|191,214 SSSHHHHHHHHHHHHH?-HHHHHHHHHHHHHHHHHH?S--??TTHHHHH----HHHHHHHH-------------------HHHHHH?------S?-------HHHH-?HHHHHHHHHHHHHHHHHHHHHHHHT-T?--??H-HHHHHHHHHHHHHHHHHTT---S?-------------------?----?HHHHHHHHHHHHHHHHHHHHHHTT--------????????-???????--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------????????----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------? 2RKL|A PF04655.9_APH_6_hur_seed 9 271 !Q:6,19|22,24|29,29|36,37|40,43|59,60|62,63|69,70|78,84|102,102|107,107|110,110|119,122|125,125|135,135|145,145|164,164|166,169|173,173|175,176|187,192|197,197|199,201|205,205|217,218|223,231|242,244|263,263 Q:0,5|20,21|25,28|30,35|38,39|44,58|61,61|64,68|71,77|85,101|103,106|108,109|111,118|123,124|126,134|136,144|146,163|165,165|170,172|174,174|177,186|193,196|198,198|202,204|206,216|219,222|232,241|245,262|264,270 TEEEEE--------------EE---ETTS?EEEEEE??TT????TTHHHHHHHHHHHTT??S??EEEEE--TTEEEEE??-????HHHHHHHHHHHHHHHHT?SSBB?SS?EEETTEEE????BS?HHHHTHHHH-HHHHHTTSS?HHHHHHHHHHHHTHHHHT?S????EEE?S??SGGGEEEETT------EEEE?S???EEE?HHHHHHHHHHH??TTHH---------HHHHHHHHHS???TTHHHHHHHHHHHHHHHH?GHHHHHH 3CSV|A PF04663.7_Phenol_monoox_seed 25 67 !Q:0,0|3,3|10,10|17,17|20,20|24,24|26,26|32,32|58,59 Q:1,2|4,9|11,16|18,19|21,23|25,25|27,31|33,57|60,66 ?TT?GGGGTT?EEEEEE?TT?TTS?S?EEEEE?TTSBHHHHHHHTHHHHHTTSTTTTT??STTSEEE 2INP|E PF04669.8_Polysacc_synt_4_seed 29 209 !Q:23,24|27,31|33,34|42,54|63,63|67,70|78,80|89,125|131,131|142,142|144,152|156,156|166,166|168,168|176,176|179,188 Q:0,22|25,26|32,32|35,41|55,62|64,66|71,77|81,88|126,130|132,141|143,143|153,155|157,165|167,167|169,175|177,178|189,208 HHHHHHHHHHHHHHHHHHHHHHS-?TT-----S??SSTTHHH-------------HHHHHHHH?TTT?---SHHHHHB-??STTTSSHH-------------------------------------HHHHH-HHHHHHHTTT?S?--------TTS?EEEESBTTS?S?STTEEEE?HH----------HHHHHHHHHHHTTTTGGGTT 2JYN|A PF04670.7_Gtr1_RagA_seed 32 374 !Q:5,6|21,23|30,62|76,77|85,86|94,96|109,109|111,116|123,123|127,150|152,157|176,176|179,179|187,187|192,195|216,224|228,261|263,263|268,269|287,288|290,290|318,319|324,362 Q:0,4|7,20|24,29|63,75|78,84|87,93|97,108|110,110|117,122|124,126|151,151|158,175|177,178|180,186|188,191|196,215|225,227|262,262|264,267|270,286|289,289|291,317|320,323|363,373 EEEEE??TTSSHHHHHHHHHS???TGGGGG?????----------------------------SEEEEEEEETTTE--EEEEEEE??SHHHHHH---HHTTTHHHHHTT?S------EEEEEE-ETT-----------------------?S--?---HHHHHHHHHHHHHHHHHH?TT?EEEEEEE?GGGS?---HHHHHHHHHHHHHHHHHHHH---------TTT??--------------------------------S?EEEE??TTSSHHHHHHHHHHHTT?-S?HHHHHHHHHHHHHHHTEEEEEEEETTT??EEEE??----??????-?????????-------------????TTHHHHHHHHH 1RRG|A PF04672.7_Methyltransf_19_seed 12 302 !Q:0,8|12,13|24,24|26,28|42,42|68,70|77,78|80,81|84,84|93,93|96,96|103,104|116,118|128,129|132,132|139,139|146,147|151,152|159,159|164,167|171,171|184,184|187,187|195,196|204,206|217,218|220,226|236,237|242,242|245,245|254,255|260,283|286,287|291,292|300,301 Q:9,11|14,23|25,25|29,41|43,67|71,76|79,79|82,83|85,92|94,95|97,102|105,115|119,127|130,131|133,138|140,145|148,150|153,158|160,163|168,170|172,183|185,186|188,194|197,203|207,216|219,219|227,235|238,241|243,244|246,253|256,259|284,285|288,290|293,299 ?????????TTS??HHHHHHHHHT?S???HHHHHHHHHHHHH?TTHHHHHHHHHHHHHHHHHHHHHTS???EEEEES??S??SS?HHHHHHHH?TT?EEEEEE??HHHHHTTHHHH???SSSEEEEEE??TT?HHHHHT?HHHHTT??TTS??EEEEES?GGGS---?GGG?HHHHHHHHHTTS?TT?EEEEEEE??TTSHHHH---HHHHHHHHHT--T???????HHHHHGGGT--TSEE?TT?SEEGGGSS??TTTT------------------------TT??GGG??EEEEEEE?? 3GO4|A PF04673.7_Cyclase_polyket_seed 23 104 !Q:1,1|17,19|29,30|40,40|48,48|52,53|63,63|83,83|85,87|92,92|95,103 Q:0,0|2,16|20,28|31,39|41,47|49,51|54,62|64,82|84,84|88,91|93,94 E?GGGHHHHHHHHHHHT---TSSHHHHHT??EEEEEEETT-EEEEEEE-ESS??HHHHHHTTS?GGGHHHHHHHHTTEEESST-T-??SGGG-GB????????? 1TUW|A PF04675.9_DNA_ligase_A_N_seed 154 320 !Q:0,0|7,7|14,17|20,27|32,48|57,59|62,64|66,66|70,85|96,96|98,98|100,100|104,112|114,114|120,120|128,131|138,143|148,174|176,177|187,192|195,214|218,219|221,221|232,233|235,244|247,252|269,271|273,289|302,309 Q:1,6|8,13|18,19|28,31|49,56|60,61|65,65|67,69|86,95|97,97|99,99|101,103|113,113|115,119|121,127|132,137|144,147|175,175|178,186|193,194|215,217|220,220|222,231|234,234|245,246|253,268|272,272|290,301|310,319 ?BTHHHH-HHHHHH----HH-----???HHHH-----------------HHHHHHHH---HT---S?GGG----------------HHHHHHHTTT?S-S?GGG-????????H-HHHHH-HHHHHHT--??HHHHHH------HHHH---------------------------H??HHHHHHHHH------HT???????????--???????BHH--H-HHHHHHHHHH??S----------TT------HHHHHHHHHHHHHHHS--?H-----------------HHHHHHHHHHHT?????-??HHHHHHHHHH 3W5O|A PF04679.10_DNA_ligase_A_C_seed 150 175 !Q:5,8|20,28|32,38|46,46|49,50|63,63|67,71|75,77|79,85|89,89|91,96|98,99|103,103|105,115|117,121|128,128|137,138|142,145|152,152|154,157|163,163|165,165|168,168|171,171|174,174 Q:0,4|9,19|29,31|39,45|47,48|51,62|64,66|72,74|78,78|86,88|90,90|97,97|100,102|104,104|116,116|122,127|129,136|139,141|146,151|153,153|158,162|164,164|166,167|169,170|172,173 GTTSE----EEEEEEEEETT---------TTE-------EEEEEEE?BS??HHHHHHHHHHHH-TTE-----ESS?-?T-------TEE?S------S??SEE-E----------?S??---EEEEEE-SEEEEETT??TTT----TTSSTT?E----EEEES?E-EE-EE?TT? 1VS0|A PF04683.8_Proteasom_Rpn13_seed 78 142 !Q:6,9|11,16|22,23|25,25|27,27|34,34|36,36|38,41|43,55|66,74|78,84|89,91|100,100|103,115|118,119|124,124|131,131|133,133|139,140 Q:0,5|10,10|17,21|24,24|26,26|28,33|35,35|37,37|42,42|56,65|75,77|85,88|92,99|101,102|116,117|120,123|125,130|132,132|134,138|141,141 EEEEEE----T------TEEEE??S?E-EEEEEE?T-T----S?------------EEEEEEETTT-------??EEE-------EEEE--?TTTEEEEE?SS?------------SS??EEEE-EESSTT?E-EEEEE??S 2Z4D|A PF04685.8_DUF608_seed 46 639 !Q:0,15|19,24|34,41|45,46|52,54|61,66|68,76|79,80|88,122|137,138|142,210|213,215|233,234|236,241|244,244|246,247|250,250|252,254|257,299|301,304|331,356|378,394|400,403|408,440|449,449|451,463|472,478|482,482|484,484|488,489|499,524|526,533|537,550|559,559|563,568|574,574|582,582|595,597|600,601|603,605|608,614|616,620|625,625|632,632|636,636 Q:16,18|25,33|42,44|47,51|55,60|67,67|77,78|81,87|123,136|139,141|211,212|216,232|235,235|242,243|245,245|248,249|251,251|255,256|300,300|305,330|357,377|395,399|404,407|441,448|450,450|464,471|479,481|483,483|485,487|490,498|525,525|534,536|551,558|560,562|569,573|575,581|583,594|598,599|602,602|606,607|615,615|621,624|626,631|633,635|637,638 ----------?-????HHH------HHHHHHHHH--------TTT??HHHHH---HHHHHH------H??-------SS??SSGGGBH-----------------------------------HHHHHHHHHHHHHH--HHH??-------------------------------------------------------------------HH---HHHHHHHHHHHHHHHHH--T------TB?T--TS?B???TT------------------------------------------?B????SSEEHHHHHHHHHHHHHHHHHHHHHT?-------------------------HHHHHHHHHHHHHHHHHHHHH-----------------HEETT----TTEE?--------------------------------SEEETTEE?S?----------??HHHHHHHH-------HTT?S?HHH--HHHHHHHTT--------------------------T?-------TTS----------????SHHHHHHH-HHH------HHHTT?HHHHHHH-HHHHHHHHHTTT?--SS??S???TT??-----G-----GGGG?BTTBTT?GGG?TH 1V7W|A PF04686.7_SsgA_seed 27 117 !Q:0,0|13,13|23,23|25,25|28,32|34,34|49,50|52,52|67,68|78,82|85,89|111,111|114,114 Q:1,12|14,22|24,24|26,27|33,33|35,48|51,51|53,66|69,77|83,84|90,110|112,113|115,116 ?EEEEEEEEEETT-STTEEEEEE-E?SS--???E-EEEEEHHHHHHHTT--S?EEETTEEEEEEEET--TEEEEEEEE---??TT?---?EEEEEEHHHHHHHHHHHHHHS?TT?HH 3CM1|A PF04691.7_ApoC-I_seed 6 61 !Q:0,3|8,11|32,32|59,60 Q:4,7|12,31|33,58 ????SSST----TTSSHHHHHHHHHHHHHTTT?SSSSSSSHHHHHHHHHHHHHHHHSSS?? 1EZE|A PF04692.8_PDGF_N_seed 10 104 !Q:0,5|16,18|28,29|31,97|99,100|102,103 Q:6,15|19,27|30,30|98,98|101,101 ??????HHHHHHHHTS???SHHHHHHHS??S??----------------????????????????????-----????--??????????------??B??B?? 3MJG|A PF04695.8_Pex14_N_seed 53 207 !Q:0,1|13,13|21,22|35,36|49,206 Q:2,12|14,20|23,34|37,48 ??HHHHHHHHHHH?STTGGGS?-HHHHHHHHHHTT??HHHHHHHHHHHT???-------------------------------------?????----------------------------------------------------------------------------------------------------------------? 2W84|A PF04699.9_P16-Arc_seed 36 215 !Q:0,1|6,6|11,11|14,42|54,54|66,67|70,72|91,91|93,96|99,99|108,113|118,118|132,164|169,185|200,200|210,210|213,214 Q:2,5|7,10|12,13|43,53|55,65|68,69|73,90|92,92|97,98|100,107|114,117|119,131|165,168|186,199|201,209|211,212 ??GGGS?GGGG?TT????????-------------????????HHHHHHHHHTT?HHHHHHHHTSS??TT???HHHHHHHHHHHHHHHHHS?H----HH-HHHHHHTS-----?HHHH-HHHHHHHHHHHTS??-------------------------------SSHH-----------------HHHHHHHHHHHHHH?HHHHHHHHH?SS?? 2P9I|G PF04703.7_FaeA_seed 5 71 !Q:0,0|11,20|22,25|36,36|57,58|64,64 Q:1,10|21,21|26,35|37,56|59,63|65,70 ?HHHHHHHHHH----------S????HHHHHHHHTS?HHHHHHHHHHHHHHTSEEEE??SSSSS?EEEESS 2HTJ|A PF04705.7_TSNR_N_seed 3 115 !Q:0,10|25,25|27,28|34,34|47,47|59,61|73,74|79,79|87,88|90,90|92,94|101,106|114,114 Q:11,24|26,26|29,33|35,46|48,58|62,72|75,78|80,86|89,89|91,91|95,100|107,113 ???????????SSTTGGGHHHHSSS?S??SEEEE?SHHHHHHHHTTT?EEEEEEEESSS???TTTTHHHHTTT??EEEE?HHHHTTT??S?S???EEEEEE??????HHHHHHS? 3NK7|A PF04710.9_Pellino_seed 8 456 !Q:0,16|24,40|47,48|51,53|63,72|84,84|88,88|97,97|108,109|113,113|117,151|153,153|156,156|167,168|175,177|185,189|192,194|196,196|200,200|204,205|208,208|213,231|242,244|249,249|252,254|259,261|263,264|267,267|271,271|274,274|288,288|302,455 Q:17,23|41,46|49,50|54,62|73,83|85,87|89,96|98,107|110,112|114,116|152,152|154,155|157,166|169,174|178,184|190,191|195,195|197,199|201,203|206,207|209,212|232,241|245,248|250,251|255,258|262,262|265,266|268,270|272,273|275,287|289,301 ?????????????----EEEEEEE????????????????-SEEEEE??SS???EEEEEEEEE-?????????EEESSSEEEEE?SSS?EEEEEEEE?TTEEEEEEES??STT?SEE????-----------????----????????????S?TT?EEEEEESSTT??EEEEEB???TTSEEEE?????EE---E?TTS?EEE??SS?EEEE???????-??????---??EEEETTEEEE???SSSS?SS???EETT???B??TT?EEE?SS?EEEEEEHHHHHHS?GGGGHHHHHHHSS?????????-----------------------------------------------------------------------------------------------------------------------------------------------?? 3EGA|A PF04711.8_ApoA-II_seed 5 76 !Q:0,5|61,63|75,75 Q:6,60|64,74 ??????THHHHHHHHHHHHHHHHHHHHHHHHHHTTTSTTHHHHHHHTTTSHHHHTHHHHTT???HHHHHHHHTTT? 2OU1|A PF04715.8_Anth_synt_I_N_seed 111 265 !Q:0,0|14,16|19,24|26,26|31,31|33,37|39,40|44,52|58,58|60,64|68,85|88,91|102,127|135,135|137,157|162,167|177,191|194,194|196,199|207,207|211,213|219,230|233,239|241,241|248,249 Q:1,13|17,18|25,25|27,30|32,32|38,38|41,43|53,57|59,59|65,67|86,87|92,101|128,134|136,136|158,161|168,176|192,193|195,195|200,206|208,210|214,218|231,232|240,240|242,247|250,264 ?TTHHHHHHTTTTT---ST------T?EEEE?T-----T??STT------??-EEEEE?S?----SEE------------------EE----EETTEEEEEE--------------------------TTEEEEE?S--------------------?HHHH------HHHHHHHTT-?????--------?TT?S--??SEEEEEE?GGG---GGGTS-???--??----SB????-??S-EEEEEE--SEEEEEETTTTEEEE 1K0E|A PF04717.7_Phage_base_V_seed 71 127 !Q:9,12|14,26|29,30|35,52|56,63|66,68|72,73|75,75|78,79|83,88|91,91|98,100|102,103|106,107|114,114|116,117|121,122|124,126 Q:0,8|13,13|27,28|31,34|53,55|64,65|69,71|74,74|76,77|80,82|89,90|92,97|101,101|104,105|108,113|115,115|118,120|123,123 EEEEEEETT----T-------------TE--EEEE------------------ETT--------EE???EEE??S?BS--SSB??????TT?EEEEEE-??T--TT??EEEEEE-E??SSS??S??? 2P5Z|X PF04719.9_TAFII28_seed 10 100 !Q:0,8|21,24|35,37|41,41|43,45|73,74|78,79|81,85|87,88 Q:9,20|25,34|38,40|42,42|46,72|75,77|80,80|86,86|89,99 -------??HHHHHHHHHHHH????HHHHHHHHHH---HHS-S???HHHHHHHHHHHHHHHHHHHHHHHHHHH--HTS??S-----S??HHHHHHHHHHH 1BH8|B PF04721.12_DUF750_seed 23 95 !Q:0,5|27,27|39,46|57,57|60,60|65,88 Q:6,26|28,38|47,56|58,59|61,64|89,94 ------EEETTTTEEEEGGGTTEEEEG?SSEESEEEEEE--------TTTTEEEEEE?TT?SEEE------------------------EEEEEE 2G9G|A PF04722.8_Ssu72_seed 27 252 !Q:0,3|26,27|30,31|38,38|56,56|59,59|61,61|73,73|75,75|78,80|97,97|100,101|106,132|154,164|166,167|174,177|199,219|221,221|223,223|240,240|242,245|251,251 Q:4,25|28,29|32,37|39,55|57,58|60,60|62,72|74,74|76,77|81,96|98,99|102,105|133,153|165,165|168,173|178,198|220,220|222,222|224,239|241,241|246,250 ???-EEEEEESSSSSHHHHHHHHHHH--TT?-EEEEEE?SSSEEEEEEETTEEEEE?TT-S?HHHHHHHHHTT?H-HH---HHHTSHHHHHHHHHHH?SS??BGGG-------------------????---?SEEEESSHHHHHHHHHHHHHS?--------??S??EEEEEE????SSHHHHHHHHHHHHHHHHHHT---------------------T?S?HHHHHHHHHHHHHHHH-S????EEEEE? 3OMX|A PF04726.8_Microvir_J_seed 3 37 !Q:0,10|12,15|17,18|20,21|24,25|27,30|34,36 Q:11,11|16,16|19,19|22,23|26,26|31,33 ???????????S????B??S??SS??S????SSS??? 2BPA|3 PF04728.8_LPP_seed 19 57 !Q:0,1|51,51|54,56 Q:2,50|52,53 ??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-TT??- 1EQ7|A PF04729.8_ASF1_hist_chap_seed 24 251 !Q:0,5|15,16|18,18|25,25|37,38|41,46|56,87|90,90|94,140|150,153|155,155|165,168|173,176|217,218|220,224|226,227|236,236|240,240|245,250 Q:6,14|17,17|19,24|26,36|39,40|47,55|88,89|91,93|141,149|154,154|156,164|169,172|177,216|219,219|225,225|228,235|237,239|241,244 ?-?---SEEEEEEEE?-S?SEETTS?EEEEEEEEESS??SS?-----EEEEEEEES?-------------------------------SS?GGG-----------------------------------------------EEEEEEEEE????S-EEEEEEEEE????GGGS?---HHHHSEEEEEEEEEEETTEEEEEEEEEEEEEESSHHHHHS??S-----S??GGGEEEEE?TTS?EEEE?????? 2YGV|A PF04733.9_Coatomer_E_seed 7 294 !Q:0,2|15,15|27,29|50,50|59,59|63,64|79,79|97,100|102,102|118,118|129,131|148,148|163,163|166,166|181,181|183,183|201,203|219,219|234,234|237,237|253,254|269,269|272,272 Q:3,14|16,26|30,49|51,58|60,62|65,78|80,96|101,101|103,117|119,128|132,147|149,162|164,165|167,180|182,182|184,200|204,218|220,233|235,236|238,252|255,268|270,271|273,293 --?TTHHHHHHHHTT?HHHHHHHHHHS???SHHHHHHHHHHHHHHHHHTT?HHHHHHHS?TTS-?HHHHHHHHHHHHHH?STTHHHHHHHHHHHHHS????S?HHHHHHHHHHHHHTT?HHHHHHHHTT?-?SHHHHHHHHHHHHHTT?HHHHHHHHHHHHHH?TT?HHHHHHHHHHHHHH?T-THHHHHHHHHHHHHHHS???HHHHHHHHHHHHHTT?HHHHHHHHHHHHHH?TT?HHHHHHHHHHHHHTT??HHHHHHHHHHHHHH?TT?HHHHHHHHHHHHHHHHHHHHS 3MV3|B PF04734.8_Ceramidase_alk_seed 42 925 !Q:10,14|23,24|27,27|35,36|45,46|51,60|71,73|87,88|92,92|95,96|105,106|112,115|123,127|132,133|155,155|157,160|171,172|179,179|186,186|188,191|194,200|204,206|216,216|219,220|228,231|233,233|236,236|239,240|244,244|259,334|338,338|344,344|347,347|353,382|385,386|388,391|394,394|416,420|422,423|427,427|429,431|441,441|444,444|447,457|462,462|466,466|469,473|476,521|524,532|534,546|553,553|555,561|571,572|574,575|578,579|582,583|587,587|590,590|608,608|613,613|633,650|656,656|661,663|666,667|674,675|681,681|684,684|705,733|735,735|738,739|741,752|755,756|759,759|763,767|770,770|775,776|778,778|785,787|791,795|799,799|809,825|828,831|848,854|860,863|873,883|886,887|898,898|902,902|906,910|918,920 Q:0,9|15,22|25,26|28,34|37,44|47,50|61,70|74,86|89,91|93,94|97,104|107,111|116,122|128,131|134,154|156,156|161,170|173,178|180,185|187,187|192,193|201,203|207,215|217,218|221,227|232,232|234,235|237,238|241,243|245,258|335,337|339,343|345,346|348,352|383,384|387,387|392,393|395,415|421,421|424,426|428,428|432,440|442,443|445,446|458,461|463,465|467,468|474,475|522,523|533,533|547,552|554,554|562,570|573,573|576,577|580,581|584,586|588,589|591,607|609,612|614,632|651,655|657,660|664,665|668,673|676,680|682,683|685,704|734,734|736,737|740,740|753,754|757,758|760,762|768,769|771,774|777,777|779,784|788,790|796,798|800,808|826,827|832,847|855,859|864,872|884,885|888,897|899,901|903,905|911,917|921,924 SEEEEEEEEE?????EEEEEESS??TT?EEEEESS??EEEEEEEE--ESSS--------??EEEEEEESSS???HHHHHHHHHHHHH--HST-TT??TTTEEEEE??BSBEE????SSHHHHG-----GGTB??HHHHHHHHHHHHHHHHHHHTT?E----EEEEEEEEEE??SSEEES?HHHHTT?S--??TT?------TTS???EEEEEEEEE-TT??EEEEEEE????B?SS?TT??EEB?HHHHHHHHHHHHTT?-------------------------------------------------------------------------?-STT?EEEEE?SS?TTEEE???-------------------------??TT??T----TS?HHHHHHHHHHHHHHHHHHHHH-----H??EEE?S?--EEEEEEEEE?TT?EE?----------GGGS-SSS?EE?????EE????????????--------?----------------?----????SS??-------H-------------HHHHTT?S?-?????HHHHHHTTT??E--EE??TT?-SSS?SS?SEEEEEEEEETTEEEEE?SSEE?HHHHHHHHHHHHHHHGGGT??----------------EEEEE?SBSS???EE??HHHHHH??TTTTS?TT?TTHHHHHHHHHHHHHHHHHH?------???----????------?????G-GG??B?????-??????TT??TT?EEE?--??SE-EETT-?E-EEEEEE???GGG--???TTS?SEEEEEEES-----------------SS????EEEEETTSTTEEEEEE-------EETTT----EEEEEEEEE?---------?TT??SEEEEEEEEE-EEE?TTT?---?EEEEEEE???EEEE 2ZWS|A PF04739.10_AMPKBI_seed 56 245 !Q:0,25|30,30|42,198|200,201|203,203|206,211|214,215|234,239|244,245 Q:26,29|31,41|199,199|202,202|204,205|212,213|216,233|240,243 ?-------???---?????---????GGGT?HHHHHHHHHHH??----------???????????????????????--------??????---------------------------------------------------------------------------?????????---------????-----??????S??B?EE??--??SS--EEEEEEEEEETTEEEEEE------EEEE?- 3T4N|B PF04744.7_Monooxygenase_B_seed 5 388 !Q:0,0|5,5|22,22|29,29|40,40|43,44|48,49|76,76|79,79|81,83|86,86|97,97|99,99|114,114|128,128|132,134|138,138|142,142|176,177|189,190|194,195|225,234|236,246|248,253|267,267|279,279|283,283|291,291|294,294|298,298|302,306|308,310|318,318|323,324|326,326|328,328|331,331|341,341|348,348|357,358|372,372|382,382|386,387 Q:1,4|6,21|23,28|30,39|41,42|45,47|50,75|77,78|80,80|84,85|87,96|98,98|100,113|115,127|129,131|135,137|139,141|143,175|178,188|191,193|196,224|235,235|247,247|254,266|268,278|280,282|284,290|292,293|295,297|299,301|307,307|311,317|319,322|325,325|327,327|329,330|332,340|342,347|349,356|359,371|373,381|383,385 ?SSSS?HHHHHSSEEEEEEEES?SEEETT?EEEEEEEEEE?TT??TTS??SSSEEEEEESSSTTEEEEEEEETTEE?SS?B???TT?EEEEEEEEEE?S?EEEEEEEEEEESSS?EEEEEEEEEEEES?GGG???EEE?TTS?EEETTTTTHHHHHHHHHHHHHHHHHHHHHHHTS??SHHHHHHHHSS??SSS??TTHHHHHHHHHHHHHHHHHHHHHHHTTSS??????????B???????????S------EEEEEEEEEEESS?SEEEEEEEEEE?SSS?EEEEEEE?SS?EEE?TTT???-?S???TTTEETT?EEES??S?B?TT?EEEEEEEEE?THHHHS?GGGGGGSS??EEEEEEEEEETTS?EEEEEEEEE?EEE?? 3RFR|A PF04748.8_Polysacc_deac_2_seed 134 248 !Q:8,13|22,22|25,25|31,31|45,47|52,52|61,79|81,81|84,85|103,104|111,111|117,117|126,131|138,138|140,140|145,148|151,151|162,163|167,168|172,176|179,180|198,198|201,202|205,205|209,209|213,213|221,221|237,238|241,242|244,244|246,247 Q:0,7|14,21|23,24|26,30|32,44|48,51|53,60|80,80|82,83|86,102|105,110|112,116|118,125|132,137|139,139|141,144|149,150|152,161|164,166|169,171|177,178|181,197|199,200|203,204|206,208|210,212|214,220|222,236|239,240|243,243|245,245 EEEEEESS----??TTHHHHHT?SS?EEEEE?SSSTTHHHHHHHH---HHTT?EEEEEEEE????----????-??????B?TT??HHHHHHHHHHHHHHSTT??EEEEEE?TTGGG?HHHHHHHH------HHHHHT-T?EEEE????SS?SHHHHHHHTT??EEE??EES?---?TT??HHHHHHHHHHHHHHHHT-TS??EE-EEE?STT-HHHHHHH-HGGGHHHHHHTTEEE??GG--G-G?? 2QV5|A PF04751.9_DUF615_seed 90 252 !Q:0,20|34,34|42,48|51,51|62,65|85,89|102,135|158,162|164,164|166,179|193,194|212,221|223,239 Q:21,33|35,41|49,50|52,61|66,84|90,101|136,157|163,163|165,165|180,192|195,211|222,222|240,251 ??---????????????????HHHHHHHHHHTTS?HHHHTTS----???HH-HHHHHHHGGG?--?SHHHHHHHHHHHHHHGGGS----?HHHHHHHHHHHH----------------------------------HHHHHHHHHHHHHHHHHHHHHH-----S?H--------------HHHHHHHHHSTTS-?HHHHHHHHHHHHHHHHT----------T??----?----------HHHHHHHHHHHH 2P0T|A PF04758.9_Ribosomal_S30_seed 23 67 !Q:0,2|4,5|16,29|42,45|49,53|55,57|59,61|64,66 Q:3,3|6,15|30,41|46,48|54,54|58,58|62,63 ???S??TTTTHHHHHS?????????-????HHHHHHHHHHHH----TTS?????S---S???SS??? 3J0O|X PF04760.10_IF2_N_seed 141 65 !Q:0,0|14,21|30,30|34,37|39,42|50,50 Q:1,13|22,29|31,33|38,38|43,49|51,64 ?TTEEHHHHHHHHT-----?-?HHHHHHHH-HHH----T??-?SSTTSEE?HHHHHHHHHHHHHH 4B3X|A PF04768.8_DUF619_seed 33 281 !Q:13,13|18,22|32,51|53,53|67,67|74,74|83,83|87,87|93,93|96,98|105,109|111,111|114,156|159,159|167,167|174,174|185,185|189,189|192,192|201,201|205,205|212,212|218,230|241,259|268,274 Q:0,12|14,17|23,31|52,52|54,66|68,73|75,82|84,86|88,92|94,95|99,104|110,110|112,113|157,158|160,166|168,173|175,184|186,188|190,191|193,200|202,204|206,211|213,217|231,240|260,267|275,280 THHHHTTSSSTTS-EEEE?????EEESSGGGS--------------------S?HHHHHHHHTTSTT-TSSSSS?HHHHHHHH-HTS?EEEEE?TT--?SEEEEE-----E?SS-------------------------------------------SS?EEEEEEE?HHHHHT-THHHHHHHHH-HHH?SS-EEEEEETT?TTH-HHHHHH?SEEEE-------------ETTEEEEEES----------------???HHHHHHHH-------HHHHHT 3S7Y|A PF04772.7_Flu_B_M2_seed 4 109 !Q:0,44|84,84|86,86|101,108 Q:45,83|85,85|87,100 -------------------------????????????????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?B?SSSBHHHHHHHHHH???????? 2LJC|A PF04773.8_FecR_seed 182 197 !Q:1,16|20,23|25,32|34,44|49,53|57,62|64,64|68,68|71,71|74,83|86,86|89,90|96,97|100,104|109,112|114,114|119,122|125,131|133,136|141,142|144,144|146,146|153,153|155,156|159,160|163,172|175,175|183,187|194,194|197,197 Q:0,0|17,19|24,24|33,33|45,48|54,56|63,63|65,67|69,70|72,73|84,85|87,88|91,95|98,99|105,108|113,113|115,118|123,124|132,132|137,140|143,143|145,145|147,152|154,154|157,158|161,162|173,174|176,182|188,193|195,196 E----------------EEE??--T--------T?---------?EEEE---?-TTS-----?E-EEE?TT?EE----------EE?SS??SSSEE--EE-----EEEE----E-EEEE??-?TT-------S?---EEEE?-S-S?EEEESS-E--EE--EE----------EE?TTSSEEE-----EEEEEE?EE- 4M0N|A PF04774.10_HABP4_PAI-RBP1_seed 39 158 !Q:0,119|121,123|132,132|134,157 Q:120,120|124,131|133,133 ??????????????-----???????????-?????????????????-????????????????-???-???-???????????????----????--------??????????---??S--?HHHHHHHT-T???????????---???-?????? 3J3A|h PF04775.9_Bile_Hydr_Trans_seed 37 162 !Q:3,4|11,12|15,15|25,38|40,44|46,47|57,58|62,62|69,69|71,72|76,77|80,80|88,88|91,93|98,104|106,111|113,113|115,115|127,127|130,137|150,150|153,153 Q:0,2|5,10|13,14|16,24|39,39|45,45|48,56|59,61|63,68|70,70|73,75|78,79|81,87|89,90|94,97|105,105|112,112|114,114|116,126|128,129|138,149|151,152|154,161 TTS??EEEEES??TT?EEEEEEEEE--?-----------T-----T??EEEEEEEEE??TTS?EETTTS?B?-EES??BS?TTHHHHT?EE---SSTT???????T------T-S?EEEEEEEEESS?SS-----???EEEEEEEEEESS?TT?EEEEEEET 3K2I|A PF04777.8_Evr1_Alr_seed 59 153 !Q:14,16|19,23|27,36|39,41|54,54|57,57|70,73|75,76|78,94|110,111|119,139|141,142|146,146 Q:0,13|17,18|24,26|37,38|42,53|55,56|58,69|74,74|77,77|95,109|112,118|140,140|143,145|147,152 HHHHHHHHHHHHTS?--SS---??HHH----------HH---HHHHHHHHHHHH?SS-HHHHHHHHHHHH----H--S???-------------?SSHHHHHHHHHHHHH--HHHHHTT????----------------?G--GGH-HHHHTT 3TD7|A PF04785.7_Rhabdo_M2_seed 4 202 !Q:0,30|33,47|62,62|65,65|82,83|85,85|103,104|124,124|127,127|129,130|133,134|161,161|164,165|172,173|185,186|190,190|193,193|196,196|200,201 Q:31,32|48,61|63,64|66,81|84,84|86,102|105,123|125,126|128,128|131,132|135,160|162,163|166,171|174,184|187,189|191,192|194,195|197,199 ???????????????????????????????EE???????????????EEEEEEEEEEEEEE?TT?EEHHHHHHHHTTGGGT??S?GGGHHHHHHHHHHHHTS??EEETTEEEEEEEEEEEEEE?TT?S??TT??EEEEEEEEEEETTEEEEEEEEEEEEE?SS??EETTSS??HHHHHHHHHTT??EEE?SS?TT?EEE?? 2W2S|A PF04792.7_LcrV_seed 2 326 !Q:0,27|43,43|47,61|63,63|66,66|79,79|84,90|107,108|111,111|131,133|148,149|187,187|191,193|195,196|202,202|204,204|222,223|228,228|236,237|244,244|250,252|255,256|262,281|324,325 Q:28,42|44,46|62,62|64,65|67,78|80,83|91,106|109,110|112,130|134,147|150,186|188,190|194,194|197,201|203,203|205,221|224,227|229,235|238,243|245,249|253,254|257,261|282,323 --------------??--------????HHHHHHHHHHHHHTT?EEE???????????????B?TT?HHHHHHHHHHHS?GGGS???????HHHHHHHHHHHHHHHH--SS?SEEEHHHHHHHHHHHHSTT???HHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSEEE?STT???S??GGGTT?S-SHHHHHTSHHHHHHTTS??EEEE?SSSEEEE??HHHHHT?SSSSS???SS??SEEES????????????????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTT?? 1R6F|A PF04794.7_YdjC_seed 114 373 !Q:0,0|28,29|34,34|41,41|52,54|56,60|62,62|64,64|70,70|72,73|76,79|81,84|86,86|88,88|96,96|98,111|113,113|115,115|117,118|121,130|136,137|155,155|159,160|162,162|185,185|190,196|198,209|212,227|239,243|245,248|253,255|260,260|265,281|293,293|295,296|298,315|322,326|328,334|337,337|342,342|345,350|362,362 Q:1,27|30,33|35,40|42,51|55,55|61,61|63,63|65,69|71,71|74,75|80,80|85,85|87,87|89,95|97,97|112,112|114,114|116,116|119,120|131,135|138,154|156,158|161,161|163,184|186,189|197,197|210,211|228,238|244,244|249,252|256,259|261,264|282,292|294,294|297,297|316,321|327,327|335,336|338,341|343,344|351,361|363,372 ?EEEEEEEEETSSHHHHHHHHHHHHSSS??EEEE?TTSTTH-HHHHHHHHHH--?T-----T?E-EEEEE?S??TT???-S----S?T-TTSGGGB?T--------------T-S?B??HH----------HHTTT??HHHHHHHHHHHHHHHGG-GSS??S?EEEGGGGGGSSHHHHHHHHHHH-HHHT?-----?B-??------???SG----------------GGGGGGGGTTT-----S??-?SEEE???SGGG?SHHH-----------------HHHHHHHHHHS-S?-S------------------EEEEEE-????B------?HH-HHHH?SS-----?THHHHHHHHHT?HHHHHHHHHT 2E67|A PF04799.8_Fzo_mitofusin_seed 11 172 !Q:0,108|167,169|171,171 Q:109,166|170,170 ????????--??????----------??????-------------------------------------------------------------????????????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---T? 1T3J|A PF04800.7_ETC_C1_NDUFA4_seed 6 114 !Q:0,0|6,7|10,12|17,18|20,21|28,28|31,34|36,38|42,42|44,44|46,48|52,54|75,75|80,82|85,113 Q:1,5|8,9|13,16|19,19|22,27|29,30|35,35|39,41|43,43|45,45|49,51|55,74|76,79|83,84 ?EEEEE??SS???TTTT??S??EEEEEE-EE?--?S???TTT?S?S???SEE---EEEEEESSHHHHHHHHHHHT?EEEE???TT???????????-------??????????? 2LJU|A PF04806.7_EspF_seed 3 47 !Q:0,2|6,14|17,21|23,47 Q:3,5|15,16|22,22 ???GGG?????????SS?????S????????----------------- 2LNH|C PF04809.8_HupH_C_seed 36 125 !Q:0,2|18,20|25,27|31,31|36,38|50,52|57,57|60,63|70,70|82,82|86,86|98,98|103,104|110,111|121,121 Q:3,17|21,24|28,30|32,35|39,49|53,56|58,59|64,69|71,81|83,85|87,97|99,102|105,109|112,120|122,124 ---TTTHHHHHHHHHHHH---HHHH???EEE?GGGS???HHHHHHHHHHH???SEEE-EE????EEEEEE?SSTTEEEEEEE?TTS?EEEEEEEESSS?GGGS??HHHHH--HHHHHHHHH-HTT 3SB1|A PF04810.10_zf-Sec23_Sec24_seed 133 45 !Q:0,2|4,4|6,7|10,11|13,14|17,17|22,23|30,30|34,36|40,41|45,45 Q:3,3|5,5|8,9|12,12|15,16|18,21|24,29|31,33|37,39|42,44 ???B?S--SS??B??TT?EEET--TTTEEE?TTT??-EEE??GGG- 1M2V|A PF04811.10_Sec23_trunk_seed 22 291 !Q:0,3|11,12|14,17|33,33|37,45|48,48|66,67|70,70|80,82|91,119|139,142|145,147|151,155|172,172|175,176|185,187|192,193|195,195|198,198|202,205|213,214|236,236|244,244|247,249|262,263|269,269|272,278 Q:4,10|13,13|18,32|34,36|46,47|49,65|68,69|71,79|83,90|120,138|143,144|148,150|156,171|173,174|177,184|188,191|194,194|196,197|199,201|206,212|215,235|237,243|245,246|250,261|264,268|270,271|279,290 ????EEEEEEE??S?---HHHHHHHHHHHHHHH-TTS?--------TT?EEEEEEESSEEEEEESS??SS?EEEEEETTS???SHHHHHHH?????????-----?????????????-?SSSEEHHHHHHHHHHHHHH????SS???TTB?????HHHHHHHHHHHHHHHS?SS??EEEEEESS???SSSS??S?SB-TTS????HHHHHTT??TTHHHHHHHHHHHHHHHHHHT?EEEEEEE?SS???HHHHTHHHHHSS??EEEES?SS-------SHHHHHHHHHTT 1M2V|A PF04814.8_HNF-1_N_seed 9 250 !Q:0,157|159,160|169,174|184,184|201,202|211,213|225,228 Q:158,158|161,168|175,183|185,200|203,210|214,224|229,249 --------------------------------------------------------------------------------------------------------------------------------------------------------??????S??HHHHHHHH------HHHHHHTTS?HHHHHHHHHHHHHHTT??HHHHHHHH???HHHHHHHHHSB????HHHHHHHHHHHHHHTTTTHHH 2GYP|A PF04815.10_Sec23_helical_seed 121 139 !Q:18,39|56,58|60,61|64,64|68,81|83,84|86,87|106,111|115,115|129,130 Q:0,17|40,55|59,59|62,63|65,67|82,82|85,85|88,105|112,114|116,128|131,138 HHHHHHHHHHHHHHHHTT---???------??--------HHHHHHHHHHHHHHHH?--B??TT?GGG-------------?B??T--TTTTHHHHHHHHHHSTTT-??---TTS?HHHHHHHHHHHTT??HHHHHHHH 1M2V|A PF04816.7_DUF633_seed 13 216 !Q:5,5|45,45|54,54|60,61|65,68|76,76|94,95|104,104|140,140|143,152|159,159|166,167|194,195|210,210 Q:0,4|6,44|46,53|55,59|62,64|69,75|77,93|96,103|105,139|141,142|153,158|160,165|168,193|196,209|211,215 EEEET?STTHHHHHHHHTTSEEEEEEEESSHHHHHHHHHHHHHTT?TTTEEEEE?SGGGG??GGG??-?EEEEEEE?HHHHHHHHHHTGGGGTT??EEEEEESS?HHHHHHHHHHHTEEEEEEEEEEETTEEEEEEEEEE?SS???---?--?HHHHHH?HHHHHH??HHHHHHHHHHHHHHHHHHHHHHTSSS??HHHHHHHHHHHHHH-HHHHH 3KU1|A PF04818.8_CTD_bind_seed 41 74 !Q:15,15|19,22|24,24|28,31|50,51|73,73 Q:0,14|16,18|23,23|25,27|32,49|52,72 HHHHHHHHHHHHHHH-TTT---?S-HHH----HHHHTTHHHHHHHHHHHH--HTTSSHHHHHHHHHHHHTTSS? 2L0I|A PF04820.9_Trp_halogenase_seed 23 539 !Q:5,6|25,26|33,43|45,45|47,48|61,62|72,72|76,76|86,86|88,90|93,94|108,113|123,127|138,141|147,147|158,159|162,162|165,171|173,173|175,176|181,181|198,199|203,205|212,212|214,214|217,217|226,229|231,231|235,235|241,242|246,246|254,256|260,260|264,267|276,277|280,280|283,285|290,292|296,296|306,306|313,313|318,318|323,328|342,343|348,349|354,356|359,371|374,374|383,383|390,391|396,396|404,407|416,418|421,423|426,426|453,456|466,466|469,471|485,486|489,490|492,501|509,509|511,511|524,526|529,530|536,536 Q:0,4|7,24|27,32|44,44|46,46|49,60|63,71|73,75|77,85|87,87|91,92|95,107|114,122|128,137|142,146|148,157|160,161|163,164|172,172|174,174|177,180|182,197|200,202|206,211|213,213|215,216|218,225|230,230|232,234|236,240|243,245|247,253|257,259|261,263|268,275|278,279|281,282|286,289|293,295|297,305|307,312|314,317|319,322|329,341|344,347|350,353|357,358|372,373|375,382|384,389|392,395|397,403|408,415|419,420|424,425|427,452|457,465|467,468|472,484|487,488|491,491|502,508|510,510|512,523|527,528|531,535|537,538 EEEEE??SHHHHHHHHHHHHHTTTS--SEEEEE???????????E-E??THHHHHTHHHHT??HHHHHHHHT?EEE?EEEEESSSS?S???SS??EETTEESEEEEES??--??EETTEEHHH-----HHHHHHHTTS????HHHHH?SHHHHHHTTB-?SB?TT-----??B?S??EEEE?HHHHHHHHHHHHHHHS??EEE???EEEEEE?T-TS?EEEEEETT----S?EEE?SEEEE??GGG?IIIIIIT???EEE?TTT????EEEEEEEE??HH-HH???SSEE---EEE?SSEEEEEEE?SSEEEE-EEEE?TTTS-----?HHHHHHHHHHHHT??TTTS??EEEE???EE-------------ES?SEETTEEE?GGGTEE??GGGS?HHHHHHH----HHHHHHHT???TT??-HH-HHHHHHHHHHHHHHHHHHHHHHHHHT????SSHHHHHHH-TS???HHHHHHHHHHHTT??SS??S??????????HHHHHHT?S?HHHHHHHHHHHT???SS??GGGGG?HH 2APG|A PF04824.11_Rad21_Rec8_seed 16 59 !Q:7,17|34,35|43,44|48,49|55,55 Q:0,6|18,33|36,42|45,47|50,54|56,58 HHHHHTT?????-?????HHHHHHHHHHHHHHHH--TSEEEEE-?STT??EEEEE?GGG 1W1W|E PF04828.9_GFA_seed 59 124 !Q:3,4|8,10|13,14|26,26|30,33|37,37|40,40|46,52|60,60|67,68|74,78|80,81|84,89|99,99|105,115|119,119 Q:0,2|5,7|11,12|15,25|27,29|34,36|38,39|41,45|53,59|61,66|69,73|79,79|82,83|90,98|100,104|116,118|120,123 EEE??SSS???TT-?SSEEEEEEEGG-GEE----EEE?GG-GEEES?------TTSSEEE-EEETTT??EEEEE-----E??TT------STTTTEEEE?GGGBS--????????-EEE-SGGG 1X6M|A PF04832.7_SOUL_seed 71 276 !Q:0,5|8,9|11,13|15,17|20,22|29,30|35,43|49,49|51,52|57,57|70,73|76,77|81,92|94,94|101,122|127,152|160,162|167,168|171,176|181,181|189,191|202,204|224,228|230,234|237,245|252,254|258,259|261,261|266,267|275,275 Q:6,7|10,10|14,14|18,19|23,28|31,34|44,48|50,50|53,56|58,69|74,75|78,80|93,93|95,100|123,126|153,159|163,166|169,170|177,180|182,188|192,201|205,223|229,229|235,236|246,251|255,257|260,260|262,265|268,274 ??????EE??S?-?S???SS---SEEEEE??EEEE---------EEEEE?S?-HHHH-HHHHHHHHHHHH----HT?-BTT-----???????S?EEEEEE?--------------------?SSSS???-----------------------EEEEEEE?-?TTTS--SS---???BSST-TEEEEEE-??EEEEEEEESS???HHHHHHHHHHHHHHHHHHT---??B----?SS--------?EEEEES---SSS--S?SSSS?-EEEEEEB? 4AYZ|A PF04839.8_PSRP-3_Ycf65_seed 24 49 !Q:0,0|2,3|10,10|26,26 Q:1,1|4,9|11,25|27,48 ?S??EEETTS?HHHHHHHHHHHSTTS?HHHHHHHHHHHHHHHHHHHHHH 2KT9|A PF04840.7_Vps16_C_seed 5 336 !Q:0,16|25,25|27,27|40,40|53,53|69,69|93,102|115,115|129,131|133,133|151,151|154,154|163,163|166,168|183,183|185,186|189,190|203,203|216,217|234,234|245,245|247,248|251,251|264,264|274,276|278,281|283,283|293,335 Q:17,24|26,26|28,39|41,52|54,68|70,92|103,114|116,128|132,132|134,150|152,153|155,162|164,165|169,182|184,184|187,188|191,202|204,215|218,233|235,244|246,246|249,250|252,263|265,273|277,277|282,282|284,292 -????????????????HHHHTTTT?S?TTTSHHHHHHTT?TTHHHHHHHHHT?HHHHHHHHHHHHHHS?HHHHHHHHHTSHHHHHHHHHHHT??????-???HHHHHHHHHHTT?HHHHHHHHHHHHT---T?SSHHHHHHHHHHHHHSS?TT?HHHHHHHH-HH---HHHHHHHHHHHHHH?S??TT??HHHHHHHHHHTT?TTHHHHHHHHTT??HHHHHHHHHHHHHTTT?HHHHHHHTTS-S??TT?SHHHHHHHHTTS?HHHHTTSTT???S???-S?SHHHHHHTS?????????????????????????????????--???????? 4KMO|B PF04843.7_Herpes_teg_N_seed 23 204 !Q:2,3|6,7|11,11|33,36|67,69|72,73|75,75|78,79|84,84|91,105|116,116|120,120|123,123|128,128|133,134|148,148|150,150|166,167|170,170|176,176|178,178|183,185|188,188 Q:0,1|4,5|8,10|12,32|37,66|70,71|74,74|76,77|80,83|85,90|106,115|117,119|121,122|124,127|129,132|135,147|149,149|151,165|168,169|171,175|177,177|179,182|186,187|189,203 SS-?TT?-GGG?TTTTTTHHHHHHHHHHHHHHH?---SGGGSSHHHHHHHHHHHHHHHHHHHHHHHH---HT??S?SS??GGGS?SEEEET---------------TEEEEEEEBS?EEE?SS?EEET-TEEE??HHHHHHHHHTSSS?E-EEEEEETTEEEEEEE?-SS?EEEEE?S?BTTB---SS?EEEEESSHHHHHHHH 2J7Q|A PF04845.8_PurA_seed 6 267 !Q:0,0|34,34|37,44|51,51|73,77|79,80|83,85|88,112|148,162|187,266 Q:1,33|35,36|45,50|52,72|78,78|81,82|86,87|113,147|163,186 ?EEEEEEEEEETTEEEEEEEEEETTEEEEEEEEE?TT?------?EEEEEE?HHHHHHHHHHHHHHHHHHHTS?----S??SS???TT?------------------------EEEEEEEEETTEEEEEEEEEETTEEEEEEEEEESS?-----------???EEEEEEGGGHHHHHHHHHHHHHHH??------------------------------------------------------------------------------ 3K44|A PF04847.7_Calcipressin_seed 9 275 !Q:10,18|29,29|32,32|47,47|62,73|82,88|92,97|100,105|107,108|110,274 Q:0,9|19,28|30,31|33,46|48,61|74,81|89,91|98,99|106,106|109,109 GGGGSTTTHH---------HHHHHHHHTT?SS?EEEEETTTTEEEEE?SSTTHHHHHHHTST------------TSEETTEE------?EEE??--??SS?----?S??S???????--------------------------------------------------------------------------------------------------------?-------------------------------------------------???? 1WEY|A PF04850.7_Baculo_E66_seed 28 496 !Q:4,4|16,17|20,20|22,23|28,28|31,33|35,36|44,46|62,62|71,73|77,77|79,83|87,87|90,91|93,93|100,101|108,110|112,132|138,139|142,142|145,145|150,173|178,178|182,183|189,189|194,194|197,197|199,199|235,236|239,239|243,248|259,262|265,266|268,271|282,283|285,285|297,298|303,310|314,315|321,334|341,341|349,349|361,369|374,374|380,398|403,403|417,417|432,433|436,446|461,461|464,465|472,473|484,485|488,490|496,496 Q:0,3|5,15|18,19|21,21|24,27|29,30|34,34|37,43|47,61|63,70|74,76|78,78|84,86|88,89|92,92|94,99|102,107|111,111|133,137|140,141|143,144|146,149|174,177|179,181|184,188|190,193|195,196|198,198|200,234|237,238|240,242|249,258|263,264|267,267|272,281|284,284|286,296|299,302|311,313|316,320|335,340|342,348|350,360|370,373|375,379|399,402|404,416|418,431|434,435|447,460|462,463|466,471|474,483|486,487|491,495 GGGS?HHHHHHHHHTT??TT?B??GGGS?TT???B?-TTGGGSS???SEEEEETTTTEEEEE?SSEEEEEE???TTS?S-----EEE?SS??S?HHHHHH??EEEETT---S?????---?------------TTTTT??TT?EE-SSSS??------------?????-----SSSS?EEE??SEEEE-EEEE?SS?E-EEEEEEEEGGGTTEEEEEEEEEETTEEEEEEEEEE??TT?STT----??EEEEEEEEET----TS??S-???HHHHHHHTTT??T-TEEETTEEEEE??BTTB---?????EEE??STTEE--------------EEEEEE?HHHHHTT?EEEEEEEEETT?----????EEEE?SSTTE-------------------EEEE?SSSEEEEEETTEE-EEEETTEEEEEETT??SE-----------EEHHHHHHHHHHTT?TT??EEESSE--EEETTEEEES??SS???EEEEE- 3VSM|A PF04851.10_ResIII_seed 55 339 !Q:0,4|22,53|61,61|65,65|72,80|82,84|92,97|100,101|104,104|108,110|116,142|146,146|152,185|188,188|198,230|236,236|240,240|242,259|265,293|299,314|322,327|334,334|336,336 Q:5,21|54,60|62,64|66,71|81,81|85,91|98,99|102,103|105,107|111,115|143,145|147,151|186,187|189,197|231,235|237,239|241,241|260,264|294,298|315,321|328,333|335,335|337,338 ?????HHHHHHHHHHHHHHHTT-------------------------------?SEEEEEE?TTS?HHHHHH---------H---HHHHHHH------TT??SS?SSS???EEEEE---??????????????----------TTT?SSEEE???????---------------------------SS?SEEEEEGGG???????------------------------??GGGGS?TTS?S------------------EEEES????????????----------------?HHHHH----------------HSTTSEE------EEEESS?S?TT 2YKG|A PF04857.15_CAF1_seed 27 798 !Q:0,0|3,3|21,21|23,25|35,35|37,53|69,69|80,80|92,101|105,127|131,134|140,150|167,168|176,176|178,178|180,181|190,220|240,240|243,246|249,419|434,434|438,440|445,445|448,449|454,455|457,457|494,495|515,526|540,541|544,547|560,633|636,654|657,657|659,660|674,691|695,695|699,783 Q:1,2|4,20|22,22|26,34|36,36|54,68|70,79|81,91|102,104|128,130|135,139|151,166|169,175|177,177|179,179|182,189|221,239|241,242|247,248|420,433|435,437|441,444|446,447|450,453|456,456|458,493|496,514|527,539|542,543|548,559|634,635|655,656|658,658|661,673|692,694|696,698|784,797 ?EE?HHHHHHHHHHHHHHHHH?S---EEEEEEEES?S?????????--??????HHHHHHHHHHHTTTB?EEEEEEEEEE-EETTTTEEEEE----------EEE-----------------------EEB????SSTTS???--------EEEEEHHHHHHHHTTT??HHHHHTT?B?B??HHHHHHHT???????????????????????????????GGGHHHHHHHHHHHHHHHT?SS????EE??-----------------------------------------------------------------------------------------------------------------------------------------------------------------------??HHHHHHHHHHHTTS?TTT???EEEE?TT??EEEE??S?SSSSTTTTHHHHHHHHHHHHHHHSBTHHHHHHHHTT??EEEESSTHHHHHHHHHHHT-?-------???SSHHHHHHHHHHH?-SS----EEEHHHHHTSTT--------------------------------------------------------------------------ST-------------------TT?S??SHHHHHHHTTSTT-------------?????EEE?TTS????-------------------------------------------------------------------------????????HHHHHHHHHHHHHH 3G10|A PF04860.7_Phage_portal_seed 127 486 !Q:0,14|22,22|28,29|35,35|44,44|50,54|59,59|62,62|64,79|82,90|107,107|111,111|117,120|122,125|127,127|129,131|134,136|138,140|144,146|149,149|151,172|174,177|181,195|198,201|207,209|211,211|214,214|220,221|223,223|225,226|228,236|240,241|245,245|267,268|270,272|279,280|282,282|284,288|290,291|297,299|308,308|310,310|313,313|318,321|326,326|328,342|344,344|351,355|358,359|361,361|367,367|382,383|389,400|426,431|435,439|441,441|448,467|469,472|475,475|478,481 Q:15,21|23,27|30,34|36,43|45,49|55,58|60,61|63,63|80,81|91,106|108,110|112,116|121,121|126,126|128,128|132,133|137,137|141,143|147,148|150,150|173,173|178,180|196,197|202,206|210,210|212,213|215,219|222,222|224,224|227,227|237,239|242,244|246,266|269,269|273,278|281,281|283,283|289,289|292,296|300,307|309,309|311,312|314,317|322,325|327,327|343,343|345,350|356,357|360,360|362,366|368,381|384,388|401,425|432,434|440,440|442,447|468,468|473,474|476,477|482,485 ??-?---???--???SHHHHTT-SHHHH--HHHHH-HHHHHHTS?EEESS?--??TTTT?SS?S---------------?SS?-----???HHHHHHHHHHHHHHHS-EEE-EEEEE--?-T----T-S?--EE---E---EEE??-GG-G----------------------E----EES---------------SS?---EEESS---S-EE?GGGEE--E-E--E--------?SSS-?HHH-HTHHHHHHHHHHHHHHHHHHH??E---EEEEEE--E?S?????H--HHHHH---HHHHHHHH-H-HT-TTSS----EEEE?S---------------S-EEEEEE-----EE??H-HHHHH-HHHHHHHHHHHHHT??TTTTT????????????HHHHHHHHHHTTTHHHHHHHHHHHT------STT-----T?TTTTTS?-------------------E----EE?TH----HHHH 3KDR|A PF04863.8_EGF_alliinase_seed 6 58 !Q:0,1|17,18|24,25|29,29|31,31|36,36|38,39|42,42|51,51|54,54|57,57 Q:2,16|19,23|26,28|30,30|32,35|37,37|40,41|43,50|52,53|55,56 ??TTHHHHHHHHHHHTS??TTSEE??TTS?E-ETTE-E??EE?TTEESTTS?EE?SS? 2HOR|A PF04864.8_Alliinase_C_seed 10 379 !Q:2,3|5,7|22,26|31,31|35,36|39,41|44,45|63,64|67,67|88,89|93,93|97,98|104,104|107,108|118,120|134,137|139,139|141,141|153,153|157,162|165,167|173,174|178,178|181,181|187,189|191,191|193,194|207,207|211,212|218,219|237,238|265,266|292,292|296,300|302,302|313,316|324,324|329,329|337,337|343,343|351,352|360,360|363,363 Q:0,1|4,4|8,21|27,30|32,34|37,38|42,43|46,62|65,66|68,87|90,92|94,96|99,103|105,106|109,117|121,133|138,138|140,140|142,152|154,156|163,164|168,172|175,177|179,180|182,186|190,190|192,192|195,206|208,210|213,217|220,236|239,264|267,291|293,295|301,301|303,312|317,323|325,328|330,336|338,342|344,350|353,359|361,362|364,378 EE??S???GGGHHHHTTSHHHH?????TTTT?SSS?-SS??-TT??HHHHHHHHHHHHHHTSB??TT?EEEEESHHHHHHHHHHHHHS??TTT?TTS??EEEEE?SS??HHHHHHHHH???TTEEEEEEGGGGT----T?S?GGGEEEEEESS?TTT??????SS---TTSEE--EEE?TT?STTTS???S?B??SEEEEEHHHHTS?GGG??EEEEE??HHHHHHHHHHHHHHTSS??HHHHHHHHHHHHHHHHHHHHHTTSTT--SHHHHHHHHHHHHHHHHHHHHTTSS-SEE?????S?EEETTTTEEE????SEEEEEE?SGGG?SHHHHHH-HTTEE?EEGGGGT??TTEEEEE?SS?HHHHHHHHHHHHHHH 3BWO|A PF04868.7_PDE6_gamma_seed 5 85 !Q:0,7|10,10|15,15|18,20|25,27|30,30|35,36|39,39|41,41|46,49|52,52|57,57|64,65|72,73|76,77|82,84 Q:8,9|11,14|16,17|21,24|28,29|31,34|37,38|40,40|42,45|50,51|53,56|58,63|66,71|74,75|78,81 ?????--?TT?SSSS?SS???SSSS???SS?SSSS??SS?S?SSSS????SS?SSSS?SHHHHT??TTTTTT??SS??GGGS??? 3JWR|C PF04869.9_Uso1_p115_head_seed 26 437 !Q:1,1|11,11|14,42|55,55|58,62|64,64|82,82|95,99|102,147|149,152|163,171|174,174|192,192|196,199|206,215|218,219|224,225|232,242|250,253|255,275|293,293|314,317|321,322|344,345|347,348|352,352|365,365|387,388|390,390|393,395|400,413|417,418 Q:0,0|2,10|12,13|43,54|56,57|63,63|65,81|83,94|100,101|148,148|153,162|172,173|175,191|193,195|200,205|216,217|220,223|226,231|243,249|254,254|276,292|294,313|318,320|323,343|346,346|349,351|353,364|366,386|389,389|391,392|396,399|414,416|419,436 T?HHHHHHHHT?EE------------------------?????EEHHHHHHHHHT?TT-----S?HHHHHHHHHHHHHHHTT?HHHHHHHHHTTS?????SS----------------------------------------------S????HHHHHHHHHT---------SS?HHHHHHHHHHHHHHHTT?HHH----HHHHTT?---------EE??SSSS??EEHHHH-----------HHHHTTT----T??-------------------HHHHHHHHHHHHHHHTT?HHHHHHHHTSTTHHHHHHHH----HHS??TTTTHHHHHHHHHHHHHHHHT??S??SSS?HHHHHHHHHHHT?HHHHHHHHHTTTTSTTHHHHT--T?SS???SSGG--------------GTT??HHHHHHHHHHHHHHHHHT 2W3C|A PF04873.8_EIN3_seed 59 494 !Q:0,109|112,120|123,170|176,180|188,189|195,195|199,200|204,205|210,212|214,223|231,233|236,245|249,250|266,266|286,287|289,290|306,322|324,324|326,493 Q:110,111|121,122|171,175|181,187|190,194|196,198|201,203|206,209|213,213|224,230|234,235|246,248|251,265|267,285|288,288|291,305|323,323|325,325 ---------------?--------?-------------???????----------------------------------------------??-----------------ST---------TS-----------------------------------------------?HHHHH-----HHHHHHS--SSSSS?TTS??TTT??HHHH???S--------??HHHHHHT-??TT??---?????GGG??HHHHHHHHHHHHHHT-GGGHHHHHHTTTTSSSSTT--T??SHHHHHHHHHHTTTT-----------------T?S?----??-------------------------------------------------------------------------------------------------?-----------------------------------???------------------------- 1WIJ|A PF04879.11_Molybdop_Fe4S4_seed 65 81 !Q:7,7|9,9|14,15|24,24|26,26|30,31|35,46|51,51|54,54|59,63|65,67|77,77|80,80 Q:0,6|8,8|10,13|16,23|25,25|27,29|32,34|47,50|52,53|55,58|64,64|68,76|78,79 SEEEEEE?S-SBTT??EEEEEEES?S?TTS??EEE------------EEEE?TT?TTTT-----T???HHHHTTHHH-HT? 2IV2|X PF04880.8_NUDE_C_seed 3 217 !Q:23,26|34,216 Q:0,22|27,33 HHHHHHHHHHHHHHHHHHHHHHH----HHHHHHH?????????????????-????????????--------------------------------------------------------------------------------------------------------------------------------------------------------- 2V66|B PF04881.8_Adeno_GP19K_seed 6 168 !Q:11,11|20,20|26,26|40,40|45,45|48,51|59,70|75,80|88,89|91,91|96,105|117,118|120,167 Q:0,10|12,19|21,25|27,39|41,44|46,47|52,58|71,74|81,87|90,90|92,95|106,116|119,119 EEEEEEEETTE-EEEEEEEE?SSSEE-EEEETTEEESSEE-EEEE?TT?-??EEEEEEE------------ETTE------EEEEEEE??H-HHHH----------HHHTHHHHHTT??S?---------------------------------------------?? 4E5X|G PF04882.7_Peroxin-3_seed 32 815 !Q:0,42|55,72|93,93|104,104|107,107|118,292|339,423|426,474|485,486|494,494|514,515|518,518|537,544|547,569|576,620|638,639|665,665|668,712|714,727|746,747|749,787|798,799|813,813 Q:43,54|73,92|94,103|105,106|108,117|293,338|424,425|475,484|487,493|495,513|516,517|519,536|545,546|570,575|621,637|640,664|666,667|713,713|728,745|748,748|788,797|800,812|814,814 -------------------------------------------HHHHHHHHHHHH------------------HHHHHHHHHHHHHHHHHHHH-HHHHHHHHHH-HS?HHHHHHHHTT?-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------?SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT--------------------------------------------------------------------------???????????SS?------------------------------------------------HHHHHHHHGG--GHHHHTH-HHHHHHHHHHHHHHHHHTT??SS?EEEHHHHHHHHHHHHHHH--------HT?--------??????????????GGGGTS?-------------??------------????????????-----HHHHHHHHHHHHHHHHH--TSHHHHHHHHHHHHHHHHHHHHHHH-TT?????????-------------------------???????????E--------------EEHHHHHHHHHTTHHHHT??S---------------------------------------TTSHHHHHHT-?HHHHHHHHHHHHH-H 3AJB|A PF04896.7_AmoC_seed 9 261 !Q:0,20|50,50|87,89|92,92|95,96|137,140|175,260 Q:21,49|51,86|90,91|93,94|97,136|141,174 ??????????-??????????THHHHHHHHHHHHHHHHHHTTTGGGTTTT?TTSTTSTTTTTTTTTTHHHHHHHHHHHHHHHHHHTS?--SS?SS??HHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTHHHHHTTS????TTSHHHHIIIIIHHHHHHHHHHHTTHHHHSSSSS??-??????????????????????????????????????????????????????????????????????-????????---? 3RFR|C PF04898.9_Glu_syn_central_seed 37 391 !Q:9,10|27,28|31,31|33,35|37,38|42,42|45,47|55,58|62,65|71,80|83,83|85,89|91,94|98,110|115,116|120,147|151,151|155,165|169,174|177,178|181,185|187,214|216,216|218,218|238,238|240,242|248,251|254,256|260,262|264,265|267,269|285,285|289,291|295,295|298,299|312,312|316,317|342,346|371,372|381,382|389,389 Q:0,8|11,26|29,30|32,32|36,36|39,41|43,44|48,54|59,61|66,70|81,82|84,84|90,90|95,97|111,114|117,119|148,150|152,154|166,168|175,176|179,180|186,186|215,215|217,217|219,237|239,239|243,247|252,253|257,259|263,263|266,266|270,284|286,288|292,294|296,297|300,311|313,315|318,341|347,370|373,380|383,388|390,390 HHHHHHHHT??HHHHHHTHHHHHHHSS??EE?S???S??TTT?SS???GGGGEEE????SSS????TTTTG----------GG?B?????S????SSS?????--??????SSSB??HHH----------------------------HHH-HHH-----------SSS??????SB??SS-----S----------------------------S?S-HHHHHHHHHHHHHHHHHTT?S???EESSG----GG???SSS-??B??H---HHHHHHHHHHHHTTT?TTT???EEE?SS??SHHHHHHHHHTT?SEE??HHHHHHHHHHHSSHHHHHHHTTTS?????HHHHHHHHHHHHHHHHHHHHHTTT??BHHHHHHS??EEESSB?H 1LLW|A PF04900.7_Fcf1_seed 60 131 !Q:6,9|27,32|42,42|47,51|54,56|58,60|70,72|75,77|80,80|83,92|97,97|99,99|108,108|113,115|120,123|128,130 Q:0,5|10,26|33,41|43,46|52,53|57,57|61,69|73,74|78,79|81,82|93,96|98,98|100,107|109,112|116,119|124,127 HHHTTS---?EEEEEEHHHHHHHHHHT-----?HHHHHHHTT-SEEE?????SS---S???HHHHHHHHH--?BT---TB?TT?---------EEEE?S?HHHHHHHH-TSTT-??EEEE?-??EEEE??? 1O4W|A PF04901.8_RAMP_seed 19 115 !Q:18,18|24,24|48,49|52,52|70,114 Q:0,17|19,23|25,47|50,51|53,69 HHHHHTHHHHHHHHHHHH?GGGTT?HHHHHHHHHHHHHHHHHHHHHHT??SS?HHHHHHHHHHHHHHTTT??????????????------------------------------- 2XVT|A PF04905.8_NCD2_seed 5 196 !Q:0,41|43,43|62,65|76,76|90,90|93,93|104,105|109,109|111,113|116,118|120,120|125,148|162,162|168,168|186,187|189,191|195,196 Q:42,42|44,61|66,75|77,89|91,92|94,103|106,108|110,110|114,115|119,119|121,124|149,161|163,167|169,185|188,188|192,194 ??--------?---------??---------??-------??S?HHHHHHHHHHHHHHHHHS????HHHHHHHHHH?SHHHHHHTHHHHS?SS?HHHHHHHHHH??SSS?S???TT???S?SSHH------------------------HHHHHHHHHHHHH?GGGGT?HHHHHHHHHHHHHHHHH??S???SSS?- 2YUF|A PF04908.10_SH3BGR_seed 6 104 !Q:0,1|7,7|10,10|12,12|31,32|41,43|54,59|63,64|69,70|72,72|95,95|102,103 Q:2,6|8,9|11,11|13,30|33,40|44,53|60,62|65,68|71,71|73,94|96,101 ??EEEEE?SS?S?HHHHHHHHHHHHHHHHTT??EEEEETTT--?HHHHHHHHHS?----?TTT??SSSS??S?EEEETTEEEEEHHHHHHHHTTT?HHHHHT?? 3GRX|A PF04909.9_Amidohydro_2_seed 132 688 !Q:6,8|10,13|21,23|28,38|63,63|76,78|81,84|88,91|93,93|97,98|101,101|103,103|105,108|112,115|119,119|121,121|128,139|141,142|144,148|153,153|155,156|158,158|160,161|169,172|176,177|179,179|181,182|184,189|199,252|256,257|260,279|282,283|287,287|296,296|301,344|349,358|364,364|366,372|376,376|379,404|406,408|411,422|436,437|441,447|459,459|463,466|469,469|472,480|490,519|526,528|533,535|540,540|548,549|551,551|563,567|570,571|574,578|583,585|590,591|593,595|600,624|631,632|635,635|641,641|644,644|646,666|669,669|687,687 Q:0,5|9,9|14,20|24,27|39,62|64,75|79,80|85,87|92,92|94,96|99,100|102,102|104,104|109,111|116,118|120,120|122,127|140,140|143,143|149,152|154,154|157,157|159,159|162,168|173,175|178,178|180,180|183,183|190,198|253,255|258,259|280,281|284,286|288,295|297,300|345,348|359,363|365,365|373,375|377,378|405,405|409,410|423,435|438,440|448,458|460,462|467,468|470,471|481,489|520,525|529,532|536,539|541,547|550,550|552,562|568,569|572,573|579,582|586,589|592,592|596,599|625,630|633,634|636,640|642,643|645,645|667,668|670,686 EEEEEE???S????HHHHHSS???EEEE-----------EEETTEEEEEETTEEEEEEEGGGT?HHHHHHHHHHHT??-EE----EEE--??G-GGG-?TT-S?H----HHH----HHH-H-HHHHHH------------H--H-----HHHH-H--S-T--TTEEEEE???-TTS--H-H--H------HHHHHHHHH------------------------------------------------------HTS??SE--------------------EE--EES-EETTEETT?GGGH--------------------------------------------HHHH----------HHHHH-T-?-----EEE-EE------------------------??S???SG------------GGSSTTHHHHTHH--HHH-------HHHHHHHHHHT-THH----HH?TT-------??EEESGGGTT------------------------------HHHHHH---HHHH---HHHH?HHHHSSS??S?GGGGTTSSEEE???-?SH--HH-----HHHH---HHHH?-T---TSEE????---------------------BTSTTS-?SS-TTHHH-HT?T---------------------TS?HHHHHHHHTHHHHHHHT? 3NUR|A PF04914.7_DltD_C_seed 36 136 !Q:3,4|7,7|16,16|20,21|30,32|35,36|54,54|61,64|73,74|94,96|100,100|103,103|109,109|115,115|117,117|135,135 Q:0,2|5,6|8,15|17,19|22,29|33,34|37,53|55,60|65,72|75,93|97,99|101,102|104,108|110,114|116,116|118,134 SSS??HH-HHHHHTGG-GHH--HHTTTTTT???SS-?THHHHHHHHHHHHHHTT?EEEEEE????HHHHHHTT??HHHHHHHHHHHHHHHHTTT???EEE?TT?TTSTT?BSSSS?B?TTHHHHHHHHHHHHHHS? 3BMA|A PF04915.7_DltD_N_seed 32 65 !Q:9,10|16,16|26,26|30,30|36,36|43,44|47,47|57,58|60,60 Q:0,8|11,15|17,25|27,29|31,35|37,42|45,46|48,56|59,59|61,64 HHHHHHHTT??HHHHH?HHHHHHHHT?SSS?EEEEE?SSTTTS??TT?HHHHHHHTT?-S?EEEE 3BMA|A PF04916.8_Phospholip_B_seed 6 740 !Q:0,17|26,29|43,44|46,68|70,76|99,99|101,103|106,106|132,132|140,140|143,143|145,145|168,172|175,175|178,178|201,205|208,214|232,240|245,267|270,271|276,276|280,287|294,294|301,303|310,312|321,321|323,323|326,326|333,333|336,336|339,339|342,342|345,345|358,364|371,372|376,378|390,390|404,406|408,408|410,410|419,419|422,424|427,440|442,443|448,466|475,479|486,486|489,490|501,501|504,504|515,518|530,530|547,548|559,561|565,568|573,573|576,588|594,595|602,602|608,608|611,623|625,625|628,628|632,632|634,635|640,647|652,657|659,659|664,670|674,674|679,682|686,690|694,696|701,701|708,710|713,714|717,721|726,739 Q:18,25|30,42|45,45|69,69|77,98|100,100|104,105|107,131|133,139|141,142|144,144|146,167|173,174|176,177|179,200|206,207|215,231|241,244|268,269|272,275|277,279|288,293|295,300|304,309|313,320|322,322|324,325|327,332|334,335|337,338|340,341|343,344|346,357|365,370|373,375|379,389|391,403|407,407|409,409|411,418|420,421|425,426|441,441|444,447|467,474|480,485|487,488|491,500|502,503|505,514|519,529|531,546|549,558|562,564|569,572|574,575|589,593|596,601|603,607|609,610|624,624|626,627|629,631|633,633|636,639|648,651|658,658|660,663|671,673|675,678|683,685|691,693|697,700|702,707|711,712|715,716|722,725 -----?-----------?SEEEEEEE----EETTTTEEEEEES??T-----------------------T?------SEEEEEEEETTTTSEEEEEEEE?T---TS?HHHHHHHHHHHHHHHTHHHHHHHHH-HSSSSTT?TT?S?HHHHHHHHHHHHHHHHHHHHHH-----HH?TT?HHHHHHHHHHHHHHHHHHHHTT?????SS???--??TTTTTTTTTTTTHHHHH---------HHTT??-???--------????-????EE--EEEE?GGG?------?EEEEEE?EEEGGG???EEEEEE???BSSSSTTS?B?TT?EEEEEE?SS?SS?SS?EE-EETTTEEEEEEE??--???GGGGGG??SSS???HHHHHHHHHHH?SSHHHHHHHHHTT?-?S?S?EEEEEEET-TS-??TT???----------?S--SSSE-------------------EEEEEETT-----EEEEEE?HH--HHHHHSEEEE?SS?SSHHHHHHTT?---HHHHHHHGGGS?TTTSHHHHHHHHHGGG??SHHHHHHHHT???TTT---?GGGB?TT-------------SBSSB-?TTSSSS?BGGGS?TT?------------B?SS-GGG-S??SEEE-------?EEEE------E?HHHH-------HTT?EEEE----ESS---??SSS???BTTT-STTTTS?-?TT??SB?????EEES-----------??? 3FGT|A PF04918.7_DltD_M_seed 9 175 !Q:1,2|5,6|24,24|30,31|35,36|39,39|41,41|49,50|61,63|79,82|85,85|98,101|114,117|130,131|136,137|151,151|154,155|172,172|174,174 Q:0,0|3,4|7,23|25,29|32,34|37,38|40,40|42,48|51,60|64,78|83,84|86,97|102,113|118,129|132,135|138,150|152,153|156,171|173,173 E??TT??HHHHHHHHTTSHHHHTT?EEEEE??GGG??SS?S?HHHHTTT??HHHHHHHHHH??-SSHHHHHHHHHHHHH?---TT?TTHHHHHHHHTT????HHHHHHHHHHHH----HHHHHHHHHTTS??TTTT--HHHHHTTTTTTTS?SS??HHHHHHHHHHHHHHTT?S? 3BMA|A PF04919.7_DUF655_seed 8 278 !Q:0,2|13,14|17,18|20,20|24,26|36,37|44,45|48,136|139,139|143,143|147,150|159,159|161,162|167,167|194,198|200,200|212,213|228,231|243,245|259,264|266,266|268,268|272,273|276,277 Q:3,12|15,16|19,19|21,23|27,35|38,43|46,47|137,138|140,142|144,146|151,158|160,160|163,166|168,193|199,199|201,211|214,227|232,242|246,258|265,265|267,267|269,271|274,275 ???EEEEEEEETT??TT??S?GGG???EEEEEETTT??EEEEEE?-TT????-------------------------------------------------------------------------------------TT?EEE?SSS?--?SSEEEEEE-E??GGGS?HHHHHHHHHHHHHHHHTTHHHHHHHH?????B?SSSBGGGGSTT??HHHHHHHHHHHHHS-???SHHHHHHHSTT???HHHHHHHHHHHHH------H?T-TSS??SS?? 2I5H|A PF04925.10_SHQ1_seed 27 244 !Q:2,4|9,9|11,19|23,30|42,49|51,57|81,83|86,86|95,95|101,102|104,105|107,126|145,147|165,167|183,183|185,185|209,212|230,231|235,242 Q:0,1|5,8|10,10|20,22|31,41|50,50|58,80|84,85|87,94|96,100|103,103|106,106|127,144|148,164|168,182|184,184|186,208|213,229|232,234|243,243 HH---HHHH?S?--------TTS-???????HHHHHHHHHSS??????-?S--??---HHHHHHHHHHHHHHHHHHHHHTT???TT-HHHHHHHH?HHHHT??S??S????????????????????HHHHHHHHHHHHHTTSSS???HHHHHHHHHHHHHHHHH--?HHHHHHHHHHHHHHH-H-TSTTTTHHHHHTHHHHHHHHHHH?--?HHHHHHHHHHHHHHHHT??GGG-------?E 3UAI|D PF04926.10_PAP_RNA-bind_seed 54 277 !Q:0,0|5,6|19,19|40,47|55,55|60,60|63,63|65,66|73,74|85,130|133,134|147,147|149,176|189,190|192,193|196,217|231,234|236,236|241,241|250,251|259,260|264,265|267,276 Q:1,4|7,18|20,39|48,54|56,59|61,62|64,64|67,72|75,84|131,132|135,146|148,148|177,188|191,191|194,195|218,230|235,235|237,240|242,249|252,258|261,263|266,266 ?HHHH-?SEEEEEEEEESS?HHHHHHHHHHHHHHHHHHHH--------HHTTSTT-EEEE-EE?S??EEEEEE??SSTTHHHHTT?--------------------------------?????????????EE??SSSSSSHHHHHS?E----------------------------EEEEEEEEEEEE??S??SS------------------????HHHHHHHHHHHHT----T?TTTS?SSSEEEEE--EEEEGGG??GGG--G?????????? 1Q79|A PF04928.12_PAP_central_seed 36 413 !Q:0,8|12,13|15,20|39,39|41,42|45,45|66,66|75,76|83,83|85,85|97,99|102,103|111,111|115,115|117,124|138,138|153,153|171,171|173,173|177,177|179,180|182,184|187,187|192,195|198,199|221,221|223,226|235,235|246,246|248,248|255,255|273,274|278,280|292,293|297,310|312,312|315,319|321,326|328,335|339,341|347,347|350,350|353,353|358,359|365,366|389,397|401,402|404,404|410,412 Q:9,11|14,14|21,38|40,40|43,44|46,65|67,74|77,82|84,84|86,96|100,101|104,110|112,114|116,116|125,137|139,152|154,170|172,172|174,176|178,178|181,181|185,186|188,191|196,197|200,220|222,222|227,234|236,245|247,247|249,254|256,272|275,277|281,291|294,296|311,311|313,314|320,320|327,327|336,338|342,346|348,349|351,352|354,357|360,364|367,388|398,400|403,403|405,409 ????-----SSS??S??????HHHHHHHHHHHHHHGGGT?S??HH-HHHHHHHHHHHHHHHHHHHH-HHHHHHTT??HHHHTT?B?EEEEEHHHHHT???TT??EEEEEEE?TTS?H--------HHHTTHHHHHHHT?TTEEEEEEETTSSS?EEEEEETTEEEEEEEEE?S?SSB?T--T?-?TT?GGGG----TT??HHHHHHHHHHHHHHHHHTSSS?H----HHHHHHHH-HHHHHHHHTT?B?TTTTSB?HHHHHHHHHHHHHHSTT??HHH---HHHHHHHHHHS??TTS----?---------B?SS?????S------S???--???TTT--?GGGGG?SS?BB?SSSS??BTTTT??HHHHHHHHHHHHHHHHHHHHHH---------TTS--S?HHHHT??? 1Q79|A PF04929.7_Herpes_DNAp_acc_seed 11 454 !Q:6,6|26,26|35,37|45,45|53,53|64,64|74,74|76,82|87,87|95,95|97,97|100,100|110,110|123,126|130,130|133,136|149,149|157,159|161,164|172,173|180,181|198,201|217,217|229,229|232,232|235,235|241,241|243,243|247,249|254,254|256,256|274,275|302,305|313,453 Q:0,5|7,25|27,34|38,44|46,52|54,63|65,73|75,75|83,86|88,94|96,96|98,99|101,109|111,122|127,129|131,132|137,148|150,156|160,160|165,171|174,179|182,197|202,216|218,228|230,231|233,234|236,240|242,242|244,246|250,253|255,255|257,273|276,301|306,312 EEEEEE?TTGGGGGHHHHHHHHHHHT-TSEEEEES---GGGGGTS?EEEEEEE?SSSEEEEEEE?GGGEEEEEE?S?------TTTS?SEEEEES-B?TT?SSBHHHHHT?TTEEEEEEEEEE?---SSS?SS?--?EEEEEEEETTSS?EEEEEEE?-?S????TTTTTSS??EEEEEE??HHHHHHHHHHHHHTTT----SEEEEEEETTTTEEE-EEETTEEEEEE?EE?SS?GGGSS?S?BSS???EEEE?S?EEEEEEHHHHHHHHHHH??TTTEEEEEEEETTTEEEEEEEEBSSS????EEEEEEE?????????????------------------------------???------------------------------------------------------------???-------?------------------------ 3HSL|X PF04934.9_Med6_seed 32 288 !Q:0,0|2,3|10,32|36,39|46,46|51,52|54,56|62,64|72,73|77,111|118,120|135,135|139,139|145,147|150,184|202,206|208,209|214,215|230,232|241,260|271,274|280,287 Q:1,1|4,9|33,35|40,45|47,50|53,53|57,61|65,71|74,76|112,117|121,134|136,138|140,144|148,149|185,201|207,207|210,213|216,229|233,240|261,270|275,279 ?B??STTTTT-------------------??--SST----HHHHHH-HHHH--S???SHHHH---HHHHHHH??SSS?????????????????????-?????????????HHHHHH???STHHHHHHHHHHHS?EEE-TTEEE--?SS-----------------------------------EEEEEEETTEEEEEEEE-----E??BTTB??EEEEEEEEETTEEE???TTHHHHHH--------------------HHHHHHHHHH----HHHHT-??????? 4H61|A PF04938.7_SIP1_seed 12 303 !Q:0,0|2,20|30,40|48,48|52,52|54,69|71,86|89,89|91,92|97,100|120,133|136,136|146,189|197,197|199,199|213,213|218,220|223,228|240,241|244,245|266,270|273,279|281,281|299,300|302,302 Q:1,1|21,29|41,47|49,51|53,53|70,70|87,88|90,90|93,96|101,119|134,135|137,145|190,196|198,198|200,212|214,217|221,222|229,239|242,243|246,265|271,272|280,280|282,298|301,301 ?S????????-??????????HHHHHHHHH-----------HHHHHHS?SSE-E???????-????????B??-?------??????TT?S??HHHH----HHHHHHHHHHHHHHHHHHT??????????????SS?SHHHHHHHH????????--------????????????????-----???????HHHHTTS?H-HHHHHHHHHHHHG-GGTS???HH------HHHHHHHHHHH??SS??HHHHHHHHHHHHHHHHHGGG---??ST-------T?THHHHHHHHHHHHHHTT??S? 3S6N|2 PF04940.7_BLUF_seed 154 122 !Q:6,7|10,18|21,22|25,32|52,52|59,64|66,67|87,87|93,93|107,108|111,111|114,114|116,117|119,120 Q:0,5|8,9|19,20|23,24|33,51|53,58|65,65|68,86|88,92|94,106|109,110|112,113|115,115|118,118|121,121 EEEEEE--EE---------EE-?TT??------HHHHHHHHHHHHHHHHHHT?EEEEEE------E--TTEEEEEEEEEHHHHHHHH-HHHHT?TTEEEEEEEEEEE?-SS?SS?S-?S??E 3GFZ|A PF04945.8_YHS_seed 23 48 !Q:1,3|7,17|26,27|39,39|46,47 Q:0,0|4,6|18,25|28,38|40,45 B???GGG???----????EEETTEEE??SSHHHHHHHHT?HHHHTT?? 3N20|A PF04951.8_Peptidase_M55_seed 41 308 !Q:0,0|7,7|14,15|21,21|23,29|44,50|64,68|76,76|81,82|84,87|92,92|94,98|103,103|107,107|109,110|118,120|123,123|132,134|138,138|140,140|144,145|152,152|163,164|178,179|189,189|195,196|202,202|204,204|221,222|239,240|246,257|260,260|284,284|294,294 Q:1,6|8,13|16,20|22,22|30,43|51,63|69,75|77,80|83,83|88,91|93,93|99,102|104,106|108,108|111,117|121,122|124,131|135,137|139,139|141,143|146,151|153,162|165,177|180,188|190,194|197,201|203,203|205,220|223,238|241,245|258,259|261,283|285,293|295,307 ?EEEEEE?STTSTT??SGGGT?T-------TSTTHHHHHHHHHH-------HHHHHHHHHHHTT?----SEEEEEE?STTS??S---?TTTS?T-----TSEE-EEE-S??TTGGGTT?-?TT?SEEEEEEE???TTS-S-STT??SSSTTE-EEEEETTEEE?-HHHHHHHHHHHTT??EEEEEEEHH-HHHHH--HTTST-T?EEEEEEEEEETTEEEE??HHHHHHHHHHHHHHHH--HSGGG?-----??????SS?EEEEEESSHHHHHHHTTSTTEEE?TTSSEEEEE?SSHHHHHHHHHHH 1HI9|A PF04952.9_AstE_AspA_seed 33 357 !Q:2,2|9,9|14,15|33,37|46,46|48,48|56,62|65,65|67,71|74,76|79,99|104,105|109,121|136,136|139,139|155,155|161,163|165,165|180,183|190,194|196,207|218,219|228,239|254,254|258,258|260,273|279,279|286,286|295,295|297,297|300,300|303,303|306,306|313,313|316,316|320,321|326,329|340,340|345,345|348,348 Q:0,1|3,8|10,13|16,32|38,45|47,47|49,55|63,64|66,66|72,73|77,78|100,103|106,108|122,135|137,138|140,154|156,160|164,164|166,179|184,189|195,195|208,217|220,227|240,253|255,257|259,259|274,278|280,285|287,294|296,296|298,299|301,302|304,305|307,312|314,315|317,319|322,325|330,339|341,344|346,347|349,356 SS?EEEEEE?SSTT??HHHHHHHHHHHHHHHHB----?SEEEEEES?S?HHHHHHT?------SS?T-----TT???TT---------------------TTTT??TTS------------?HHHHHHHHHHHHTG-GG?SEEEEEEEEETTEEE?SEEEE???S?HHHHHHHHHHHHTT--??SEEEEE?????T------------THHHHHTTTT??EEEEEEEE?---????????HHHHHHHHHHHHHT-TSB?S????????-?????EEEEE?GGGEEE?SSSEEEEE?S?TT?EE?TT?EEEEEE?TT?SSS??EEEE?---SSSEEEEEEE?SEEE?TT?EEEEEEEE 3NA6|A PF04954.8_SIP_seed 169 219 !Q:23,27|30,30|44,59|69,69|72,83|86,86|92,92|98,167|170,176|181,181|190,190|201,204|207,207|216,216 Q:0,22|28,29|31,43|60,68|70,71|84,85|87,91|93,97|168,169|177,180|182,189|191,200|205,206|208,215|217,218 SSEEEEEEEGGGHHHHHHHHHHS---?-TT?EEEEEEEESSGGG-??????--------?TEEEEEEEE?SS?----------?TT?HHHHH-HHTTS??---------------------------------------------?----------------------SS------?EEEE-EEEEHHHH-HHHHHHHHHH????GG-GEEEEEEE?TT 2GPJ|A PF04957.7_RMF_seed 27 57 !Q:0,4|24,25|27,30|32,32|37,37|55,56 Q:5,23|26,26|31,31|33,36|38,54 ?????HHHHHHHHHHHHHHHHTTT??S????S-SHHH-HHHHHHHHHHHHHHTSS?? 2JRM|A PF04958.7_AstA_seed 71 388 !Q:0,0|6,7|22,25|28,29|33,33|35,35|52,52|55,58|60,61|63,65|76,77|93,96|108,113|129,129|143,143|150,151|168,168|173,173|180,181|183,187|190,194|206,208|219,232|239,239|248,248|250,250|265,265|272,272|276,277|287,287|293,293|301,321|324,325|330,332|336,346|353,355|357,358|360,360|362,362|366,366|375,376|378,378|380,380|387,387 Q:1,5|8,21|26,27|30,32|34,34|36,51|53,54|59,59|62,62|66,75|78,92|97,107|114,128|130,142|144,149|152,167|169,172|174,179|182,182|188,189|195,205|209,218|233,238|240,247|249,249|251,264|266,271|273,275|278,286|288,292|294,300|322,323|326,329|333,335|347,352|356,356|359,359|361,361|363,365|367,374|377,377|379,379|381,386 ?EEEEE??GGGHHHHHHHHHHS---?TT?-TTS?S?HHHHHHHHHHHHHHHH?TT???-S??E---EEEEEEETTT??EEEEEEEESSTTSSS-???EEEEEEEEEEE------TTTTEEEEEEEEEEE?TTTTSEEEEEEEE?GGGTTS--HHHHHHHHHHHHHHHH?GGGS?SEEEEE??B???--TT?--??HHHHHTGGGTS???HHHHHHHHHH??????????????EEGGGS?HHHHHHTT?B?GGGHHHHHHHHHHT?EEEEEE?TTT??EEEEEEGGG?HHHHT?EEEEEEE?------???----???----EE--EEEE???STT---------??EEEEEE???T--T-S?EEE?HHHHHHHT??T-T?EEEEEE? 1YLE|A PF04960.10_Glutaminase_seed 17 301 !Q:3,4|13,13|16,17|26,27|34,34|36,37|40,40|66,66|69,80|85,88|90,90|109,109|128,130|133,133|144,144|159,159|161,161|164,166|183,183|200,200|204,205|207,207|209,209|237,237|239,239|243,243|255,264|272,272|276,276|280,280|297,297 Q:0,2|5,12|14,15|18,25|28,33|35,35|38,39|41,65|67,68|81,84|89,89|91,108|110,127|131,132|134,143|145,158|160,160|162,163|167,182|184,199|201,203|206,206|208,208|210,236|238,238|240,242|244,254|265,271|273,275|277,279|281,296|298,300 SEE??SSHHHHTS?TT??EEEEEETT??EEEEES?S??EE?GGGGHHHHHHHHHHHHHHHHHHHHS?SS????????????TTSS---?S?TTSHHHHHHHHHHTTTTS?HHHHHHHHHHHHHHHTTT???EE?HHHHHHHHHS?HHHHHHHHHHHHTT?S?TT??-HHHHHHHHHHHHTEEE?HHHHHHHHHHHHTTTB?TTT??B?S?HHHHHHHHHHHHHHTTGGGHHHHHHHT?S?EEE?TTSEEEEEETT----------TEEEEEE?SEE?TTS?BHHHHHHHHHHHHHBS?STT 3IH9|A PF04961.7_FTCD_C_seed 75 197 !Q:13,13|17,17|42,42|53,56|93,95|140,140|171,174|176,181|197,197 Q:0,12|14,16|18,41|43,52|57,92|96,139|141,170|175,175|182,196 SBHHHHHHHHTSS?SSS?THHHHHHHHHHHHHHHHHHHHHTS-SSTTSGGGHH----HHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHTS???SGGGTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSS?STTHHHHHHHHHHHHHHHHHHHHHHHHHHT----T?---??HHHHHHHHHHHHHHH- 2PFD|A PF04962.7_KduI_seed 72 335 !Q:0,0|3,5|7,9|14,16|21,21|26,30|35,35|43,43|46,46|51,57|68,70|73,73|79,82|85,85|87,87|93,96|102,108|110,112|117,117|120,121|127,127|131,133|139,139|144,145|147,152|154,154|157,157|172,176|184,184|188,193|196,196|203,203|205,205|208,208|212,212|214,214|217,217|224,227|232,232|245,255|263,267|269,273|287,287|296,298|302,302|305,305|309,309|316,316|319,325|328,328 Q:1,2|6,6|10,13|17,20|22,25|31,34|36,42|44,45|47,50|58,67|71,72|74,78|83,84|86,86|88,92|97,101|109,109|113,116|118,119|122,126|128,130|134,138|140,143|146,146|153,153|155,156|158,171|177,183|185,187|194,195|197,202|204,204|206,207|209,211|213,213|215,216|218,223|228,231|233,244|256,262|268,268|274,286|288,295|299,301|303,304|306,308|310,315|317,318|326,327|329,334 ?EE??-S?--SSEE---EEEE?HHHH-----TSSS?EEEEEEE?TT?EEEE?-----?SSEEEEEEEE---ES?EEEEE----TT-E-EEEEE???-SSGGG------?S???EEEE?SS??EEEEE-SSS---EEEEE-EEEE??S??--??E-EE?GGGSEEEEESSGGG?----EEEEEEE?TTS?----?SS?EEEEEE-E?TT?EES?S?EE?EEEETT----TEEE?EEEEEEEEESTT----------?EEEEEEE?----T-----TSSSEEEEEEETT?EEEESSSB?-?EEE?TT?EEE-EEEEEE?SS--?????EE?GGGGGG 1X8M|A PF04963.8_Sigma54_CBD_seed 22 206 !Q:0,1|5,5|13,28|31,32|47,47|54,54|56,56|66,71|88,89|94,94|107,110|112,114|128,129|133,136|146,175|177,177|180,205 Q:2,4|6,12|29,30|33,46|48,53|55,55|57,65|72,87|90,93|95,106|111,111|115,127|130,132|137,145|176,176|178,179 ??HHH-HHHHHHH----------------HH??SHHHHHHHHHTTSB?TTSSBS-S?HHHHHHHTT----??HHHHHHHHHHHHTSSS??TTTS?TTHHHHHHHHHS?---S---TTHHHHHHHHHHH--HHS????HHHHHHHHT??----------------------------S?SS??????-------------------- 2K9M|A PF04965.9_GPW_gp25_seed 181 173 !Q:0,7|11,11|15,21|30,31|37,65|67,67|70,70|72,72|77,79|81,85|104,105|110,110|115,116|120,120|123,130|133,144|149,149|157,158|163,165 Q:8,10|12,14|22,29|32,36|66,66|68,69|71,71|73,76|80,80|86,103|106,109|111,114|117,119|121,122|131,132|145,148|150,156|159,162|166,172 ?????---HHH-HHH-------HHHHHHHT??TTSST-----------------------------T?TT?S?GGGG???S??--?HHHHHHHHHHHHHHHHHH-?TTEE-EEEE--EEE?TT--------GG------------GTEE-EEEEEEE--ETTT---TEEEEEE 2IA7|A PF04966.7_OprB_seed 48 640 !Q:0,2|22,24|33,35|42,43|55,56|59,59|61,61|64,65|67,106|113,113|123,142|154,154|160,184|186,190|193,197|204,204|209,216|222,224|227,231|245,248|259,259|266,277|279,279|282,289|291,291|294,295|305,306|308,309|311,350|366,366|368,368|384,404|406,408|414,452|464,466|470,477|490,501|504,504|508,508|510,514|527,527|535,535|547,547|563,565|568,569|573,578|591,591|610,621|625,626|632,632|639,639 Q:3,21|25,32|36,41|44,54|57,58|60,60|62,63|66,66|107,112|114,122|143,153|155,159|185,185|191,192|198,203|205,208|217,221|225,226|232,244|249,258|260,265|278,278|280,281|290,290|292,293|296,304|307,307|310,310|351,365|367,367|369,383|405,405|409,413|453,463|467,469|478,489|502,503|505,507|509,509|515,526|528,534|536,546|548,562|566,567|570,572|579,590|592,609|622,624|627,631|633,638 ???EEEEEEEEEEEEEEHHHHT??-TTEEEEEE---EEEEEE??HHHHTTSBTTB??SS?S?TT??S?---------------------------------------SSEEEE-EEEEEEEET--------------------TTTEEEEEEEE?GGGTS-------------------------S?????SS-----SGGGSS?SHHH--------HTTTT???TT---??EEEEEEEEEEETT----EEEEEEEEEE?GGGGST------------T?TT??------S?TT??EEEEEEEEE--E??E----------------------------------------ETTEEEEEEEEEEEE?S?EEEEEEETTSSBHHH---------------------H???EEEES--------------------------------------?EEEEEEEEEEE???GGG?-------TTSEEEEEEEEE------------EE?TTT?S-----EEEEEEEEEEEE?SSTTSTT?EEEEEEEEEEE?HHHHHHHHHHHHHHT???TT--STT??????EEEEEEEEEEEE?SSSEEEEEEEEEEESGGG?-----------TTS??EEEEE-EEEEEE? 4GF4|A PF04968.7_CHORD_seed 47 75 !Q:0,1|4,5|10,11|14,15|19,25|30,32|35,35|50,50|52,54|64,66|69,70|72,74 Q:2,3|6,9|12,13|16,18|26,29|33,34|36,49|51,51|55,63|67,68|71,71 ??EE??STTT??EE?-TTT----?-?TTTB???SS?EEEETTEEEESSSS?E---ESSHHHHTT???SS?-B??? 2YRT|A PF04969.11_CS_seed 100 109 !Q:0,1|7,7|16,18|20,25|33,33|36,36|38,41|46,58|61,61|65,66|74,75|79,81|90,90|93,100|108,108 Q:2,6|8,15|19,19|26,32|34,35|37,37|42,45|59,60|62,64|67,73|76,78|82,89|91,92|101,107 ??EEEEE?SSEEEEEE???S??----GGGEEEE?SS-S?---EEEE-------------EE?TTS--SEEEEEE?-BSS???GGGEEEEE?SS--------SEEEEEE? 1WH0|A PF04970.8_LRAT_seed 32 182 !Q:0,8|11,11|19,24|43,92|99,99|113,114|116,122|125,131|135,138|149,149|153,156|159,160|162,164|178,181 Q:9,10|12,18|25,42|93,98|100,112|115,115|123,124|132,134|139,148|150,152|157,158|161,161|165,177 ???--????TT?EEEEEET------TEEEEEEEEETTEEEEEE-------???-------------????????----------?????????EEEEEE-EHHHHHTTSEEEE??G-------GG-------GTS????HHHHHHHHHH-TTT?---EE-?S???HHHHHHHHHHHHH???? 4DPZ|X PF04972.12_BON_seed 187 74 !Q:0,0|10,10|12,21|23,24|30,30|38,38|42,42|58,58|60,60|66,66|68,69|72,73 Q:1,9|11,11|22,22|25,29|31,37|39,41|43,57|59,59|61,65|67,67|70,71 ?HHHHHHHTT?T----------T-?EEEEE-ETEEEEE?EES-SHHHHHHHHHHHHHH?T-TSEEE-E??EE?? 2KGS|A PF04978.7_DUF664_seed 48 185 !Q:19,20|26,27|32,32|34,36|41,51|57,57|70,70|72,75|87,91|98,102|105,107|129,130|138,138|141,141|143,153|157,157|183,184 Q:0,18|21,25|28,31|33,33|37,40|52,56|58,69|71,71|76,86|92,97|103,104|108,128|131,137|139,140|142,142|154,156|158,182 HHHHHHHHHHHHHHHHHTT??GGGTT??BTTB?S--?HHHH-----------HHHHH-HHHHHHHHHHTT?S-???TTTSHHHHHHH-----TTTSSS??--?SS???HHHHHHHHHHHHHHHHHHHTT??HHHHTSB?TT?S-----------SBH-HHHHHHHHHHHHHHHHHHHHHHHHH?? 2QE9|A PF04979.9_IPP-2_seed 20 151 !Q:0,4|7,7|12,13|16,104|122,123|136,137|144,150 Q:5,6|8,11|14,15|105,121|124,135|138,143 ???-?EE?HHHH--HH??????????????????????????--????????????????----????????--?????????????-??????--??????--?HHHHHHHHHHHHHHHHH??GGGGHHHHHHHH--HHHHTT??????? 2O8G|I PF04983.13_RNA_pol_Rpb1_3_seed 112 365 !Q:11,14|29,54|67,67|71,172|175,178|181,181|184,184|186,222|235,235|237,250|253,253|256,263|266,267|270,284|288,288|293,293|296,296|301,302|309,317|319,319|322,322|332,332|355,360 Q:0,10|15,28|55,66|68,70|173,174|179,180|182,183|185,185|223,234|236,236|251,252|254,255|264,265|268,269|285,287|289,292|294,295|297,300|303,308|318,318|320,321|323,331|333,354|361,364 TSEETTTTEES????THHHHHHHHHHSTT-------------------------?EEETHHHHGGGG?SSS??----------------------------------------------------------------------------------------------------SS????SB?SS-S?------------------------------------EEETTHHHHTTS?S--------------SB?EE?-----??SS??SS--------------?TTT?SEEE?BS?EEEE??SHHHHS---------S?TT?HHHHSSSSS?TTTHHHHHHHHHHHHHHHHHHH?-????GGGG 1K83|A PF04984.9_Phage_sheath_1_seed 41 786 !Q:0,32|34,35|42,49|52,53|55,59|61,62|66,68|71,73|80,80|82,91|108,108|116,118|122,122|125,125|139,140|143,144|147,147|156,156|168,168|171,172|178,180|192,192|195,198|206,206|209,209|211,214|222,231|241,241|248,248|251,252|256,257|287,287|295,305|309,310|315,315|318,320|334,334|347,354|356,356|358,358|361,362|364,364|374,375|385,386|389,390|395,395|397,398|400,403|406,407|414,423|429,430|434,438|441,441|444,449|454,454|472,472|474,474|477,477|480,483|487,487|492,492|503,506|510,511|518,523|530,530|561,577|580,580|582,582|585,591|594,597|608,608|613,613|622,633|636,643|662,663|668,675|678,689|704,704|714,715|717,718|720,725|730,731|734,755|759,761|763,763|770,770|776,777|784,785 Q:33,33|36,41|50,51|54,54|60,60|63,65|69,70|74,79|81,81|92,107|109,115|119,121|123,124|126,138|141,142|145,146|148,155|157,167|169,170|173,177|181,191|193,194|199,205|207,208|210,210|215,221|232,240|242,247|249,250|253,255|258,286|288,294|306,308|311,314|316,317|321,333|335,346|355,355|357,357|359,360|363,363|365,373|376,384|387,388|391,394|396,396|399,399|404,405|408,413|424,428|431,433|439,440|442,443|450,453|455,471|473,473|475,476|478,479|484,486|488,491|493,502|507,509|512,517|524,529|531,560|578,579|581,581|583,584|592,593|598,607|609,612|614,621|634,635|644,661|664,667|676,677|690,703|705,713|716,716|719,719|726,729|732,733|756,758|762,762|764,769|771,775|778,783 ?----------?????????-????????????S??EEEEEE------??SS??B-----S??EEE-??SH---HHHHHH?S--------??TTTHHHHHHHHTTTTT?SEEEEEE???TTT?BB?BSSTTSEEEEEEE??SS??TT?EEEEEESS?EEEEEEEEEEE?SS??EEEEE???HHHHHHHHHTT?SS??-?SSEEEEE?TT?S????EEEEEEE??????????SSSHHHHTT?HHHHHH-HH--HTT??EEEESSSBGGGGGEEEEEEEHHHHHGGGT?EEEEETT---------??EEE??GGGT?SS???STTEEEEEEEETT-EEEEEEEEESST--------T?B?TT??B?BHHHHHHTT??SSEEEESTT??TT??EEEE?B??B?-??TT??HHHHHH----------HHGGG??TTT?????EE?GG------GTTS?HHHHHHHHHHHHHHHHH-H?SS?EE????HHH-HSSS?HHHHHHHHHH----HTT??SSTTSS??????SSEEEE?SEEEEEETTTTEEEEEESHHHHHHHHHHSS?????????????????SS?S?BS??--???HH----HHHHTTTTEE?EEES-SSSEEESS?????------?SS????????HHHHHHHHHHHHHHTTHH--HHHS??------SH------------HHHHHHHHHHHHHH-HHHHHHSSB?-S??S------TTSS??SS---------------------?SSS???S?EEEEEE?BSSSS??EEEEEE?? 3FOH|A PF04989.7_CmcI_seed 31 255 !Q:1,2|5,6|13,13|16,16|31,32|39,40|43,43|57,71|73,75|83,84|87,90|94,99|107,108|111,111|118,126|134,134|136,139|154,155|158,158|163,163|173,196|209,220|223,224|230,232|238,243|249,249|254,254 Q:0,0|3,4|7,12|14,15|17,30|33,38|41,42|44,56|72,72|76,82|85,86|91,93|100,106|109,110|112,117|127,133|135,135|140,153|156,157|159,162|164,172|197,208|221,222|225,229|233,237|244,248|250,253 S??SS??EETTEE?SS?HHHHHHHHHHHHHH??SEEEEE??TT?HHHHHHHHHHHHT---------------T???EEEEEES??TT????GGG?-----TTEEEEE??SS?GGGTSS????----?SSEEEEE?S?---SSHHHHHHHHHHHT??TT?EEEE?SHHHHHHHH?-----------------------HHHHHHHHHTTT------------TT--EEEET---TTTTS-----?TTTTT?EEEE? 3SSM|A PF04990.7_RNA_pol_Rpb1_7_seed 42 195 !Q:0,0|3,3|5,6|8,8|13,15|19,22|26,26|34,34|38,39|44,44|47,50|52,55|61,62|71,73|87,92|95,97|100,102|105,106|109,109|114,118|120,158|161,163|165,172|174,177|190,192|195,195 Q:1,2|4,4|7,7|9,12|16,18|23,25|27,33|35,37|40,43|45,46|51,51|56,60|63,70|74,86|93,94|98,99|103,104|107,108|110,113|119,119|159,160|164,164|173,173|178,189|193,194 ?SS?S??S?EEEE???STT????SSS?SHHHHHH-HTT?-SSTT?SS---?S????EEEEE??TTSSTTTT?-?HHHHTTSGGGSST------TS-??EE???TT-?SS?EEEE?????S---------------------------------?????-SS???S---?----S?---HHHHHHHHHHTT???SS- 1K83|A PF04992.9_RNA_pol_Rpb1_6_seed 153 343 !Q:1,1|7,7|11,11|17,17|20,22|26,37|41,43|45,46|49,50|52,52|56,68|76,78|82,82|85,85|88,90|92,99|114,134|140,145|151,154|158,159|163,163|177,185|189,190|192,194|208,208|210,212|214,250|253,280|284,292|312,312|319,319|322,324 Q:0,0|2,6|8,10|12,16|18,19|23,25|38,40|44,44|47,48|51,51|53,55|69,75|79,81|83,84|86,87|91,91|100,113|135,139|146,150|155,157|160,162|164,176|186,188|191,191|195,207|209,209|213,213|251,252|281,283|293,311|313,318|320,321|325,342 B?GGGEE-EEE?GGGSS?HH---HHH------------HHH???T--TS--S-SSS??-----------TTTBTTS---GGG-TT?HH---H--------HHHHHHHHHHHHHH---------------------HHHHH------HHTTT??-?EEE--EES?HHHHHHHHHHHTT---?----?SSS?-B???HHHHHHHHHHHHT-T-??S??------------------------------?----SS----------------------------HHH---------HHHHHHHTHHHHHHHHHHS?HHHHHH-TT???HHHHHHHHHHHHHHHHHT 1K83|A PF04993.8_TfoX_N_seed 85 118 !Q:5,8|12,12|14,15|29,29|40,40|42,44|50,52|60,60|65,72|75,75|83,86|88,88|93,94|100,100|117,117 Q:0,4|9,11|13,13|16,28|30,39|41,41|45,49|53,59|61,64|73,74|76,82|87,87|89,92|95,99|101,116 HHHHH----GGG-S??EEEEETTEEEEEE-TTEEEEEEET-T---EEEEE?-?HHHHHHH-HHTT?----???EE-EETTEEE----E?SEEE??HHHHH?HHHHHHHHHHHHHHHH? 2OD0|A PF04994.8_TfoX_C_seed 48 92 !Q:0,4|8,13|17,18|30,31|40,40|52,53|56,57|61,63|75,75|80,80 Q:5,7|14,16|19,29|32,39|41,51|54,55|58,60|64,74|76,79|81,91 ????-GGG------STT??HHHHHHHHHTT??SHHHHHHH?HHHHHHHHHHH-?TT??HHH---HHHHHHHHHTS?GGGS?HHHHHHHHHHH 3MAB|A PF04996.7_AstB_seed 4 456 !Q:0,3|11,13|16,22|25,25|34,35|37,37|57,58|63,66|69,69|78,79|93,93|102,103|107,107|116,116|130,132|154,155|163,166|172,174|189,190|199,201|204,208|212,215|230,230|240,240|248,249|286,290|296,296|301,301|309,309|318,318|320,320|323,323|359,360|368,369|380,380|388,388|393,393|409,410|412,412|414,414|420,420|440,442|444,444|449,455 Q:4,10|14,15|23,24|26,33|36,36|38,56|59,62|67,68|70,77|80,92|94,101|104,106|108,115|117,129|133,153|156,162|167,171|175,188|191,198|202,203|209,211|216,229|231,239|241,247|250,285|291,295|297,300|302,308|310,317|319,319|321,322|324,358|361,367|370,379|381,387|389,392|394,408|411,411|413,413|415,419|421,439|443,443|445,448 --??EEEEEEE???TT???????TT?HHHHHTTT??B?HHHHHHHHHHHHHHHHHTT??EEEE????SS?HHHHHHTT??SSHHHHHHHHHHH?HHHHHHTS??GGG?GGGTEEEE?TTTBSSSSEEEEE???TTSHHHHTSHHHHHHHHHHHS??TTTEEEE????SSGGG???GGGGEEEESSSTTS??EEEEEESB?--TT?????SSS????BHHHHHHHHHHTTB?GGGEEEEEB?HHHHTTT??SGGGTEEEETTEEEEETTSBTTHHHHHHHHHHHSTT----?EEEEE?TTTS?HHHHHHH?TTSSEEEE?T-TS?EEEEEETHHHHSHHHHHHHHHHHHSSSSEEEEEEE??HHHHTTT??TTTTEEEEEE?HHHHHTS?GGGB?SHHHHHHHHHHHHHH??S?B?GGGGG?HHHHHHHHHHHHHHHHHTT??-S?SGGG??????? 1YNH|A PF04997.7_RNA_pol_Rpb1_1_seed 24 434 !Q:0,5|9,12|18,18|21,27|30,30|33,33|35,35|38,38|41,42|50,61|66,81|85,86|91,98|101,104|106,106|108,109|124,124|128,130|132,133|135,135|138,141|149,155|158,158|173,177|181,186|188,189|192,208|211,239|242,242|245,251|256,256|261,262|264,270|275,275|277,277|280,289|301,301|310,311|315,317|326,326|329,330|335,339|343,350|372,374|396,396|398,399|401,401|404,408|413,417|424,424 Q:6,8|13,17|19,20|28,29|31,32|34,34|36,37|39,40|43,49|62,65|82,84|87,90|99,100|105,105|107,107|110,123|125,127|131,131|134,134|136,137|142,148|156,157|159,172|178,180|187,187|190,191|209,210|240,241|243,244|252,255|257,260|263,263|271,274|276,276|278,279|290,300|302,309|312,314|318,325|327,328|331,334|340,342|351,371|375,395|397,397|400,400|402,403|409,412|418,423|425,433 ??????BEE????HHHHH-HH???????TT?TT?S-SS-SS??SSSSSSS???---------SSSS?-------------??TTS??SSSS---?????EE????S?B??HHHHHHHHHHSSSS?TTT???S??S?SH----HHHHHHH-------SS?TTTTHHHHHHHHHH?????SST------T??SS???--------------SS??-----------------------????SS?SS???????EEET-TEEE??B?-----?SSSS?B?SS??-----???HHHHHHHHHHS?HHHHHHSS??SSS?-?GGGSSBSS?EE??GGGS?????SSS?---????TTTTHHHHHHHHHHHHHGGGG?-?SSSTTHHHHHHHHHHHHHHTT?T--T?SS?????SSSS?????HHHHHT?SSSSSTTTT 1K83|A PF04998.12_RNA_pol_Rpb1_5_seed 27 783 !Q:0,2|41,41|44,44|48,48|51,51|54,55|65,65|67,67|76,76|82,82|91,93|101,102|115,115|143,145|152,152|157,186|196,197|201,201|203,205|220,221|223,225|250,250|259,261|281,282|285,286|302,317|319,320|332,332|335,335|338,338|345,345|351,351|364,364|379,381|385,385|398,413|422,422|430,573|575,576|592,592|597,598|610,623|639,639|644,644|647,649|656,657|661,661|669,670|677,677|680,681|688,694|697,699|701,701|705,705|709,711|720,720|741,744|761,767|769,771|774,774|776,776|778,779 Q:3,40|42,43|45,47|49,50|52,53|56,64|66,66|68,75|77,81|83,90|94,100|103,114|116,142|146,151|153,156|187,195|198,200|202,202|206,219|222,222|226,249|251,258|262,280|283,284|287,301|318,318|321,331|333,334|336,337|339,344|346,350|352,363|365,378|382,384|386,397|414,421|423,429|574,574|577,591|593,596|599,609|624,638|640,643|645,646|650,655|658,660|662,668|671,676|678,679|682,687|695,696|700,700|702,704|706,708|712,719|721,740|745,760|768,768|772,773|775,775|777,777|780,782 ???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?EE?TTS?EE?TT??EEESSGGGT?B?GGGEEEEE?GGGSS?HHHHHHHH???TTSSSSS??TTTBTTSGGGTT?HHHHHHHHHHHHHHHHHHHHHHHHTTT???EEEEES?HHHH------------------------------HHHHHHHTT??SSS?B???HHHHHHHHHHHHTT??S???SSHHHHHHHHHHTHHHHHHHHHHS?HHHHHHTT???HHHHHHHHHHHHHHHHHTB??TT??HHHHHHHHHHTGGGS??-?????????????S??HHHHHHHHHHT?SS?SS?EEEEEB?GGGSS?HHHHHHHHHHHS?EEGGGTEEEEEEEE???SSS?SSGGGHHHHHTS????????????????SEEEEEEE?HHHHHHT------------------------------------------------------------------------------------------------------------------------------------------------T??HHHHHHHHHTTSTTS?EEEE??TTSSSEEEEEE??????????????HHHHHHHHHHHHHHH?EEES?TT???EEEEEE??EEE?TTSSEEE??EEEEEE-ES??HHHHTT------?TT---B?TTT?EES?--HHHHHHHT?HHHHHHHHHHHHHHHHHTTT????HHHHHHHHHHTTTBSS????---S???SS?S-S??TTS 1K83|A PF05000.12_RNA_pol_Rpb1_4_seed 106 148 !Q:6,6|8,14|17,18|25,29|36,36|44,53|63,71|74,74|83,83|86,87|97,102|109,113|121,132|135,135|138,139|146,147 Q:0,5|7,7|15,16|19,24|30,35|37,43|54,62|72,73|75,82|84,85|88,96|103,108|114,120|133,134|136,137|140,145 HTTTTT-T???--??SS??TTHHHH-----HHHHHH-HHHHHHH----------HHHHHHTTS?--------SS?TTTHHHHH?SS??HHHHHHHHT??????STTSSS???--STTSSST------------TS?SS??STTTSS?? 1K83|A PF05001.8_RNA_pol_Rpb1_R_seed 99 30 !Q:0,15|17,18|21,29 Q:16,16|19,20 ??--?-??-----?--S--SS---?-???? 3RTX|C PF05002.10_SGS_seed 48 119 !Q:0,36|38,57|69,70|85,118 Q:37,37|58,68|71,84 ?---------------------?----------????S--------------------HHHHHHHHHTT??SSHHHHHHHHHHTT?--------------------------------- 2JTT|C PF05005.10_Ocnus_seed 22 150 !Q:3,3|5,5|11,11|15,15|26,26|31,31|33,35|46,46|51,53|68,70|74,95|104,105|109,112|117,118|125,129|139,140|143,143|147,148 Q:0,2|4,4|6,10|12,14|16,25|27,30|32,32|36,45|47,50|54,67|71,73|96,103|106,108|113,116|119,124|130,138|141,142|144,146|149,149 TTT-S?SEEEE?SSS-EEEEEEEEES?GGGT?S???EEEEEEEETT?SSHH---HHHHHHHHHHHHHT?--EEE----------------------EEEEEEEE??SSS??--EEEE??BTTTBB?---?HHHHHHHHH--HH?TTS-?E 2OZW|A PF05008.10_V-SNARE_seed 89 92 !Q:16,17|20,21|23,24|26,27|56,56|59,61|63,64|84,84 Q:0,15|18,19|22,22|25,25|28,55|57,58|62,62|65,83|85,91 HHHHHHHHHHHHHHGG--GS?-T--T--THHHHHHHHHHHHHHHHHHHHHHHHHHT-TS--?T--TTHHHHHHHHHHHHHHHHH-HHHHTHH 2QYW|A PF05013.7_FGase_seed 188 337 !Q:0,1|3,3|11,18|22,23|28,29|40,48|63,67|69,80|85,85|87,91|95,96|100,100|102,102|109,133|141,141|143,146|148,150|153,160|162,163|193,193|195,197|206,206|211,212|216,230|235,235|237,248|250,258|271,276|279,295|300,300|302,303|305,305|322,322 Q:2,2|4,10|19,21|24,27|30,39|49,62|68,68|81,84|86,86|92,94|97,99|101,101|103,108|134,140|142,142|147,147|151,152|161,161|164,192|194,194|198,205|207,210|213,215|231,234|236,236|249,249|259,270|277,278|296,299|301,301|304,304|306,321|323,336 ??S-EEEEETT??????--GGG--TTTT??HHHHTSTTSS--------?TTHHHHHHHHHHHH-----T??----------EEEE?S----?TTT??TTS?T-TSTTSS------------------------?SEETTEE?G----G---GT--------T??HHHHHHHHHHTHHHHHHHHHHHHHHHHHT-T???EEEEEEEE?SEET--TEE-----------????EEEE?S------------S---??----HHHHHHHHHTTT-----?SS-------------?---EEET?S??G-GGTTTHHHHHHTGGGT?EEEEEEEEGGGGSS 2ODF|A PF05014.10_Nuc_deoxyrib_tr_seed 107 197 !Q:10,11|13,13|32,36|40,41|44,56|59,75|92,92|99,104|107,109|112,113|128,134|140,140|142,143|145,145|153,175|178,178|182,182|184,186|188,189|191,191|194,194|197,197 Q:0,9|12,12|14,31|37,39|42,43|57,58|76,91|93,98|105,106|110,111|114,127|135,139|141,141|144,144|146,152|176,177|179,181|183,183|187,187|190,190|192,193|195,196 EEEESGGGGS--T-TTTHHHHHHHHHHHHTTT?----EEE-?TT-------------TT??---------------SSHHHHHHHHHHHHHH?SEEEEE-??-??SS---SS??HHHHHHHHHHHHTT?------EEEEE?S??S?HHHHHTS-----------------------SB?TTS?B???S--S?SS?GG- 1S2L|A PF05016.9_Plasmid_stabil_seed 158 135 !Q:7,8|24,25|27,28|31,31|48,48|50,50|57,59|64,73|75,75|84,99|107,108|110,114|117,119|123,123|133,134 Q:0,6|9,23|26,26|29,30|32,47|49,49|51,56|60,63|74,74|76,83|100,106|109,109|115,116|120,122|124,132 EEEEHHH--HHHHHHHHHHHHHHH?-H--HH-HHHHHHHHHHHHHHHH-H?GGGSEE--?TTTS----------T-TEEEEEEE----------------TEEEEEE--E-----SS---SEE-EEEEEETTS?? 3KIX|y PF05019.8_Coq4_seed 27 235 !Q:7,8|12,12|14,15|17,21|33,46|70,76|78,79|87,87|104,117|140,141|158,158|162,162|180,180|188,192|198,207|210,211|215,215|229,234 Q:0,6|9,11|13,13|16,16|22,32|47,69|77,77|80,86|88,103|118,139|142,157|159,161|163,179|181,187|193,197|208,209|212,214|216,228 HHHHHHH--HHS?S??H-----HHHHHHHHHHS-------------?HHHHHHHHHHHTTSHHHHHHHHH??--???S??HHHHTTS?TTBHHHHHHHHHHHTT???---????????SHHHHHHHHHHHSHHHHHHHHT??SSHHHHHHHHHHHHHH-STT?SHHHHHHHHHHHHHHHH?GHHHHHH-----HHHHS?-------??TT??GGG?TTSBHHHHHHHTT?????? 3MSQ|A PF05023.9_Phytochelatin_seed 20 281 !Q:0,10|12,12|29,32|35,35|45,48|68,91|96,96|98,102|117,117|121,128|133,135|147,148|150,151|156,182|186,186|189,189|206,206|241,242|244,244|248,250|268,268|274,274|280,280 Q:11,11|13,28|33,34|36,44|49,67|92,95|97,97|103,116|118,120|129,132|136,146|149,149|152,155|183,185|187,188|190,205|207,240|243,243|245,247|251,267|269,273|275,279 ???????????T-TEEESSSHHHHHHHHT?---SB?TTHHHHHHH????SSGGGHHHHHHHHHHHHHT---------------??---????TTTT-T?????TTTGGGSHHHHHHS?HHH--------HHHH???HHHHHHHHHTT--T??EEEE---------------------------EGG-GS?HHHHHHHHHHHHHSTT?EEEEEEEGGGGTSSSSEEEEEEEEEETTTTEEEE??S?TTT???EEEEHHHHHHHHSSEET-TTTEE?EEEEE? 2BU3|A PF05025.8_RbsD_FucU_seed 133 156 !Q:5,7|17,18|21,21|27,27|30,37|45,47|53,53|66,66|80,84|86,88|102,103|110,111|117,117|122,122|126,126|130,131|138,141|145,146|152,155 Q:0,4|8,16|19,20|22,26|28,29|38,44|48,52|54,65|67,79|85,85|89,101|104,109|112,116|118,121|123,125|127,129|132,137|142,144|147,151 SSSSS???HHHHHHHHH??TT?EEEEE?TT???----?TTSEEEE???BTTBS?HHHHHHHHHHHS?EEEEEEETHHHHH----?H---HHHHHHHHHHHHH--HHHHTS??EEEEE?HHHH-HHH-HTT--SSEEEE????STT??EEEEE???? 2WCU|A PF05026.8_DCP2_seed 23 97 !Q:15,15|21,21|44,44|46,47|50,53|65,69|75,82|97,97 Q:0,14|16,20|22,43|45,45|48,49|54,64|70,74|83,96 HHHHHHHHHHHTTTS?HHHHT?HHHHHHHHHHHHHHHHHTTGGG?T--TS????HHHHHHHHHTT----?GGGTT?------?HHHHHHHHHHHHHB- 2QKM|B PF05028.9_PARG_cat_seed 23 546 !Q:5,8|20,31|34,35|48,49|51,66|68,68|70,70|73,74|95,96|101,114|117,117|124,127|129,129|134,138|140,140|142,142|161,167|170,173|182,200|202,202|204,205|209,219|227,227|232,233|242,243|254,255|276,279|288,292|298,298|302,302|305,326|330,336|338,338|342,350|353,353|359,370|376,377|396,400|403,404|408,477|482,482|489,489|491,491|505,523|527,528|531,531|534,534|537,537|546,546 Q:0,4|9,19|32,33|36,47|50,50|67,67|69,69|71,72|75,94|97,100|115,116|118,123|128,128|130,133|139,139|141,141|143,160|168,169|174,181|201,201|203,203|206,208|220,226|228,231|234,241|244,253|256,275|280,287|293,297|299,301|303,304|327,329|337,337|339,341|351,352|354,358|371,375|378,395|401,402|405,407|478,481|483,488|490,490|492,504|524,526|529,530|532,533|535,536|538,545 HHTTS---?HHHHHHHHHTH------------HH--HHHHHHHTHHHH??S--------------??B?B?TT??EEEEEEHHHHHHHHHHHHTT??TTSS?-------------TT?STTTTS???-S?GGGS?----S-S?THHHHHHHHHHHHHHHHH-------HS????EEEEEEEE?------------------S?B??GGG??????----?EEEESSS?HHHH-?TTSEEEEE??SSTTTTTTTT??SHHHHHHHHSGGGGGHHHHB????TTEEEEEE?????EEEES?GGG?EE----------------------EEE?????-?B?TTS?--------BS?EEEEE?????-------SSGGG--GGSHHHHHHHHHHHHHHH?---?TT??GGG??-------------------------------------------------------------------?EEEE?TTBGGG?B?HHHHHHHHHHHHH-------------------HTT??EE-EE?TT?HHHHHHHH- 4EPP|A PF05031.7_NEAT_seed 53 167 !Q:0,6|21,24|28,28|35,35|56,57|59,63|73,75|80,90|94,94|98,100|105,112|116,116|120,120|125,125|128,128|132,132|142,143|146,146|148,150|166,166 Q:7,20|25,27|29,34|36,55|58,58|64,72|76,79|91,93|95,97|101,104|113,115|117,119|121,124|126,127|129,131|133,141|144,145|147,147|151,165 ???????EEEEEEEEEEETTS----SSB?GGGGGB?SSEEEEEETTEEEEEEEEES--G-----GGEEEEEEE---ETTE-----------EEE?EEE---EEET--------TTT-EEE-EEEE-ES?TTS?EEEEEEEEE--GG-G---TEEEEEEEEEEEETT? 2O1A|A PF05033.11_Pre-SET_seed 86 297 !Q:4,5|8,11|13,13|18,26|30,50|53,53|56,56|59,59|62,62|64,93|95,126|128,150|152,156|158,160|165,166|172,176|179,199|201,201|203,206|208,208|211,211|213,228|230,230|232,273|275,276|279,281|286,289|291,291|293,293|296,297 Q:0,3|6,7|12,12|14,17|27,29|51,52|54,55|57,58|60,61|63,63|94,94|127,127|151,151|157,157|161,164|167,171|177,178|200,200|202,202|207,207|209,210|212,212|229,229|231,231|274,274|277,278|282,285|290,290|292,292|294,295 HHHH??SS----S?EEEE--------?SSS------------????--?--SS?EE?SS?EE?T------------------------------T??---???????-------------??-??--S-----------------------S-----T---TTSS?-HHHHT-----TS--??-----------------S-B---?T-TS?B?---------------S?T------------------------------------------T??EE???TTSS??--T-T?TT?- 3SW9|A PF05034.8_MAAL_N_seed 4 160 !Q:0,0|11,12|18,18|26,27|34,34|36,38|42,42|49,50|62,62|69,71|80,80|82,84|103,103|105,107|118,118|125,126|148,148 Q:1,10|13,17|19,25|28,33|35,35|39,41|43,48|51,61|63,68|72,79|81,81|85,102|104,104|108,117|119,124|127,147|149,159 ?BEEEEEEEEE??SSEEE?HHHHHHT??EETTEE?S???STT?SSSEEE??EEEEEEEETTS?EEEEEE???TTTTSTTS?S???HHHHHHHHHHHTHHHHTT?B???HHHHHHHHHH?EETTEE??HHHHHHHHHHHHHHHHHHHTS?HHHHHHHHHST 3ZVI|A PF05035.7_DGOK_seed 51 341 !Q:2,2|5,5|12,13|17,19|28,29|37,49|54,56|66,69|72,73|88,90|105,105|108,108|110,111|116,116|120,121|125,126|128,129|133,133|150,154|156,156|159,159|165,165|186,186|207,208|210,212|217,222|233,235|237,237|256,258|282,291|294,295|302,302|318,318|325,326 Q:0,1|3,4|6,11|14,16|20,27|30,36|50,53|57,65|70,71|74,87|91,104|106,107|109,109|112,115|117,119|122,124|127,127|130,132|134,149|155,155|157,158|160,164|166,185|187,206|209,209|213,216|223,232|236,236|238,255|259,281|292,293|296,301|303,317|319,324|327,340 EE?SS?EEEEEE?-TTS?--EEEEEEES??HHHHHHH?------------HHHH---HHHHHHHTT??--TT??EEEEEGGGSTTSSS???EEESSEETTHHHHT?EE?S--SSSS?EEE??EEE--E??TTS?EEESSHHHHHHHHHTT-----S?SS?EEEEE?SSSEEEEEEETTEEEEEEEE?HHHHHHHHHHHSTTHHHHTT-?S???TTSH------HHHHHHHHHH---H?GGGHHHHHHHHHHHHHHH???HHHHHHHHHHHHHHHHHHHHHTT---------?SS??EEEEEE?HHHHHHHHHHHHHTT?EEEEEE--HHHHHHHHHHHHHH 3T69|A PF05036.8_SPOR_seed 136 98 !Q:0,2|10,10|14,17|32,32|34,46|61,61|71,72|78,78|82,87|92,93 Q:3,9|11,13|18,31|33,33|47,60|62,70|73,77|79,81|88,91|94,97 ???EEEEEEE-EES---?HHHHHHHHHHHHHH-T??-----------EEEEEETTEEEEEE-EEESSHHHH--HHHHH-HHH------HHTS??EEEE 1X60|A PF05039.7_Agouti_seed 9 110 !Q:0,76|80,82|85,85|93,93|97,97|104,104|108,109 Q:77,79|83,84|86,92|94,96|98,103|105,107 -----------------------------------------?----???--------------?????--???????TTS???SS?SSSSSTT?EEE?SBTTBS?EEE?? 1Y7K|A PF05043.8_Mga_seed 33 109 !Q:0,3|15,29|41,42|44,44|58,59|76,76|80,80|84,84|86,86|94,94|96,96 Q:4,14|30,40|43,43|45,57|60,75|77,79|81,83|85,85|87,93|95,95|97,108 ????THHHHHHHGGG---------------SHHHHHHHHHH--H?SEEEHHHHHHHHT??HHHHHHHHHHHHHHHG-GGT?EEE-E?SSEEEEE-S?HHHHHHHHHHHH 3SQN|A PF05044.7_HPD_seed 13 158 !Q:0,1|3,3|17,18|20,20|32,35|69,69|71,71|79,79|92,92|95,95|99,100|122,122|140,140|143,146|149,149 Q:2,2|4,16|19,19|21,31|36,68|70,70|72,78|80,91|93,94|96,98|101,121|123,139|141,142|147,148|150,157 ??S?HHHHHHHHHHHTT??S?HHHHHHHHTSS????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?S?GGGSSSS?TTHHHHHHHHHH?SS?STT??HHHHHHHHHHHHHHHHHHHHT?TTSTHHHHHHHHHHHTT?SS????SS?GGGSGGGS 1MIJ|A PF05047.11_L51_S25_CI-B8_seed 67 90 !Q:5,5|14,14|20,21|26,31|35,39|48,78|84,84|87,88 Q:0,4|6,13|15,19|22,25|32,34|40,47|79,83|85,86|89,89 HHHHH-HHTHHHHH-HHSTT??EEEE?---??SSS----?EEEEEESS?-----------------------------?EEEEE?TT??H 1S3A|A PF05049.8_IIGP_seed 6 384 !Q:0,0|15,15|33,34|57,58|64,66|74,74|76,76|81,82|85,85|93,95|100,102|115,115|126,127|142,144|150,150|162,162|166,167|188,192|196,197|200,200|218,218|230,232|251,251|257,258|262,262|266,269|289,289|297,305|312,312|319,321|324,325|334,334|343,350|356,356|358,359 Q:1,14|16,32|35,56|59,63|67,73|75,75|77,80|83,84|86,92|96,99|103,114|116,125|128,141|145,149|151,161|163,165|168,187|193,195|198,199|201,217|219,229|233,250|252,256|259,261|263,265|270,288|290,296|306,311|313,318|322,323|326,333|335,342|351,355|357,357|360,383 ?HHHHHHHHHHHHHT?HHHHHHHHHHHHHHHHH??EEEEEEESTTSSHHHHHHHHTT??TTSTT???TTHHHHH?S?EEEE?-SS?TTEEEEE???GGGS???HHHHHHHTTGGG?SEEEEEEESS??HHHHHHHHHHHHTT???EEEEE?HHHHHHHHHHH?GGG??HHHHHHHHHHHHHHHHHHTT?????EEE??TT?TTSTTHHHHHHHHHHHS?HHHHHHHHHHS???SHHHHHHHHHHHHHHHHH-HHHHT??BSS?GGG????HHHHHHHHHHHHHHHHHTT?SHHHHHT?????????HHHHTT?SGGGTT???SS??HHHHHHHH-HHHHHHHH?------?SSSTT?B??HHHHHHHHHHHHHHHHHHHHHHHH 1TQ2|A PF05050.7_Methyltransf_21_seed 459 485 !Q:3,3|6,10|12,27|38,41|44,45|49,51|54,60|62,64|67,85|94,106|108,119|122,126|129,129|133,175|177,178|180,180|187,187|190,199|201,201|204,204|209,287|293,293|295,310|312,313|316,317|320,336|338,342|344,347|351,352|355,355|357,359|362,363|366,371|374,376|382,382|385,387|389,390|393,403|405,407|410,416|418,423|426,448|457,462|465,468|472,472|474,480|482,483 Q:0,2|4,5|11,11|28,37|42,43|46,48|52,53|61,61|65,66|86,93|107,107|120,121|127,128|130,132|176,176|179,179|181,186|188,189|200,200|202,203|205,208|288,292|294,294|311,311|314,315|318,319|337,337|343,343|348,350|353,354|356,356|360,361|364,365|372,373|377,381|383,384|388,388|391,392|404,404|408,409|417,417|424,425|449,456|463,464|469,471|473,473|481,481|484,484 EET?TT-----S----------------HHHHHHHHHH----TS??SEE---EE-------E???HH-------------------HHHHHHHH-------------H------------HH-----TT-TST-------------------------------------------T--G-GGEEEE?SE----------E?SS?EEEE???------?--------?????--------------------????-----------------------?????????EEEEE?H----------------H--HH-?SS?---------------?S-----E----EEE??SS?H---HH--HH------HT---THHHH-HH---H??EE-----------E---EE-----??S------ST-----------------------THHHHHHH------HH----HHH?T-------T??E 2PY6|A PF05051.8_COX17_seed 43 57 !Q:1,7|26,27|29,29|33,38|54,56 Q:0,0|8,25|28,28|30,32|39,53 S???--??TTTSSHHHHHHHHHHHHH--T?GGG-----?HHHHHHHHHHHHTTT??? 1U97|A PF05053.8_Menin_seed 3 734 !Q:0,3|10,11|13,13|30,30|32,33|49,57|60,61|63,64|67,67|70,71|77,77|82,82|87,87|90,90|92,92|111,112|116,118|122,124|140,140|143,144|147,147|150,151|159,163|166,168|185,186|188,188|193,193|196,196|206,206|210,211|213,214|218,221|224,225|234,234|241,242|245,246|258,260|266,266|268,268|291,291|306,307|310,312|331,332|348,348|367,370|400,421|424,424|445,445|448,451|466,466|475,601|603,604|606,669|671,674|690,691|700,733 Q:4,9|12,12|14,29|31,31|34,48|58,59|62,62|65,66|68,69|72,76|78,81|83,86|88,89|91,91|93,110|113,115|119,121|125,139|141,142|145,146|148,149|152,158|164,165|169,184|187,187|189,192|194,195|197,205|207,209|212,212|215,217|222,223|226,233|235,240|243,244|247,257|261,265|267,267|269,290|292,305|308,309|313,330|333,347|349,366|371,399|422,423|425,444|446,447|452,465|467,474|602,602|605,605|670,670|675,689|692,699 ????HHHHTT??B?SHHHHHHHHHHHTTSS-S??HHHHHHHHHHHHHHH---------HT??S??SS?TT??EEEEE?SSSS?SEEE-EE?B?HHHHHHHHHHHHHHHHTT??GGG???SSS???HHHHHHHHHHHHHTS?SS??TT?SS??SHHHHHH-----HS???HHHHHHHHHHHHHHHT??S?EEEE?SS?EEEEESGGG?EEE??S??SSS????TT??THHHHHTT?TTTGGG??EE??HHHHHHHHHHS???BSSSS?B?HHHHHHHHHHHHHHHHTTTTTT?HHHHHHHHHHHHHS??TT???HHHHHHHHHHHHHHHHTT??SHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHTTS??-?GGGHHHHHHHHHHHHTHHHHHHHHHHHHS???--?????????????????TT?HHHHHHHHHHHHHHHHHHTT?SS????HHHHHHHHHHHTTS?TTTTTSSB???------------------------------------?---------------------------------------------------------------------------------------S??S?????????????????????------------------??---?------------------?B????SHHHHTTTTGGGSSS??HHHHHHHH?????????---?????????????????????? 4I80|A PF05059.7_Orbi_VP4_seed 6 653 !Q:0,5|9,10|23,23|27,28|30,32|43,43|46,46|52,54|56,57|73,73|78,78|81,81|85,85|89,91|99,99|130,130|134,134|136,137|144,145|149,149|154,160|164,177|179,179|189,189|192,192|194,194|200,201|214,214|227,227|229,229|231,236|243,246|257,258|261,263|269,283|313,314|316,316|318,318|330,331|334,335|338,339|347,348|350,351|354,355|359,361|379,380|383,384|401,401|405,407|410,410|414,414|416,416|425,425|436,436|443,445|447,449|451,452|454,457|466,467|488,488|492,492|495,498|511,514|517,520|524,526|541,556|568,573|588,588|601,603|605,617|631,632|634,634|639,641 Q:6,8|11,22|24,26|29,29|33,42|44,45|47,51|55,55|58,72|74,77|79,80|82,84|86,88|92,98|100,129|131,133|135,135|138,143|146,148|150,153|161,163|178,178|180,188|190,191|193,193|195,199|202,213|215,226|228,228|230,230|237,242|247,256|259,260|264,268|284,312|315,315|317,317|319,329|332,333|336,337|340,346|349,349|352,353|356,358|362,378|381,382|385,400|402,404|408,409|411,413|415,415|417,424|426,435|437,442|446,446|450,450|453,453|458,465|468,487|489,491|493,494|499,510|515,516|521,523|527,540|557,567|574,587|589,600|604,604|618,630|633,633|635,638|642,652 ???-??EEE??TTTHHHHTTSSS?EEE??S???HHHHHHHHTT?SS?EEEES???S??HHHHHTTTEEEEESS-SEEE?SS?EEE?SEE?-?STTSTTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?SEE?S??HHHHHT??TTT?EEEE???????BSS????-?????????S?TTHHHHHHH?SS?S-EEEEE??TTSHHHHHHHHH?HHHHHTSEEEEE?T-T??????TTEEEE????SSTHHHHTTS??SS???EEEEE???????????????SHHHHHHHHHHHHHHHHBTTBSEEEEEEE??S-S?SEEEEEESEEE??TT??TT??EEEEEEE??S??SS??TTS???EEEEEEHHHHHHHHHHH??TT??HHHHHHHHHHHHSEEB?TTT???SS?EEE?S?TTBGGGTT?HHHHHHHHTT?SEEEEE???S???S??B????HHHHHHHH??SSEEEEEHHHHHHHHHHHST-TTS?SS????HHHHTTEEEEEE????SS????TTT???TTHHHHHHHHHHHS????????????????HHHHHHHHHHH??????HHHHHHHHHTTSSS?SGGGTSTTTTTT???S?????????????HHHHHHHHHHHHH--S?SSSS?--STTHHHHTTTS 2JHC|A PF05064.8_Nsp1_C_seed 30 131 !Q:0,55|108,130 Q:56,107 ----------------------------------------------------????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT????--------?-------??? 3T97|A PF05065.8_Phage_capsid_seed 189 487 !Q:4,11|13,23|33,34|43,46|50,74|76,90|92,102|105,106|108,108|113,115|117,117|125,125|132,133|140,142|145,145|148,150|155,158|174,180|184,185|187,189|192,213|216,216|219,223|227,228|231,232|235,256|261,264|276,282|284,287|291,291|296,296|301,302|304,304|306,310|314,318|326,331|333,335|337,342|347,350|356,356|360,371|375,394|399,400|402,403|405,405|413,417|421,421|430,449|453,453|468,468|473,475|477,477|483,483|486,486 Q:0,3|12,12|24,32|35,42|47,49|75,75|91,91|103,104|107,107|109,112|116,116|118,124|126,131|134,139|143,144|146,147|151,154|159,173|181,183|186,186|190,191|214,215|217,218|224,226|229,230|233,234|257,260|265,275|283,283|288,290|292,295|297,300|303,303|305,305|311,313|319,325|332,332|336,336|343,346|351,355|357,359|372,374|395,398|401,401|404,404|406,412|418,420|422,429|450,452|454,467|469,472|476,476|478,482|484,485 TGGG?????-??S??????????-SGGGSEEEE??SSEEEEEE?-??EEB--------------??????-----T---------------T?-----?????EE??E-EEEE---E?EEEEEEE-EEEHHH--HHHSTT---HH-HH---HHHH----HHHHHHHHHHHHHHS?-??---STT--S???HH----------------------HH?EE?---?GGG??TT??HH----------------------HHHH----HHHHHTGGGTS?---?-?E----EEE?HHHH-HHHH--T?B---?-TTS?----BTTTTTT------S???S------EETT----EEEEE?TTS-----------?TTE--------------------EEEE-?H--H-HHEEEEE-----SEE-EEEEEESS--------------------STT?TTTTEEEEEEEEEE?EEES?--G-GGEEE-EE? 3DDX|A PF05066.8_HARE-HTH_seed 67 100 !Q:1,1|14,18|20,20|37,51|61,61|68,77|80,80|83,83|88,90|96,96 Q:0,0|2,13|19,19|21,36|52,60|62,67|78,79|81,82|84,87|91,95|97,99 S?HHHHHHHHHHHH?----S?EEHHHHHHHHHHHHTS?--------------GGGGTHHHH-HHHHHH----------HT?SS?EESS---SSEEE?GGG 2KRC|A PF05067.7_Mn_catalase_seed 6 314 !Q:0,0|4,4|10,14|17,18|49,49|51,51|85,85|90,90|92,96|100,100|110,110|114,115|123,124|127,127|131,131|133,133|138,141|143,143|169,171|201,203|208,208|214,214|236,236|240,241|249,249|252,252|257,257|259,259|265,268|270,286|294,294|309,313 Q:1,3|5,9|15,16|19,48|50,50|52,84|86,89|91,91|97,99|101,109|111,113|116,122|125,126|128,130|132,132|134,137|142,142|144,168|172,200|204,207|209,213|215,235|237,239|242,248|250,251|253,256|258,258|260,264|269,269|287,293|295,308 ?EEE?SSBSS?????SS??HHHHHHHGGGTTSTTSHHHHHHHHHHHHHH?S?TTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?SSTT?S?????GGG?TTGGGGSSS?SHH--HHTSSSS??SB?TTS?B?BGGG????S?HHHHHHHHHHHHHHHHHHHHHHHTT???HHHHHHHHHHHHHHHHHHHHHHHHHHHHH???GGGG?SSSSS?GGGSHHHHHHHHTTTTTEEEE?SSS??TTGGGTS?SB?TTTS?B?EEEES????B???????----------BGGGTBS?SSTHHHHHHHHHHT??--? 1O9I|A PF05068.7_MtlR_seed 4 195 !Q:0,27|38,39|65,66|68,68|87,87|101,101|103,103|124,128|141,141|153,153|161,169|193,195 Q:28,37|40,64|67,67|69,86|88,100|102,102|104,123|129,140|142,152|154,160|170,192 ?????-----------------------HHHHHHHHHH??SHHHHHHHHHHHHHHHHHHHGGGGS??S?HHHHHHTHHHHHSTTSTT?SHHHHHHHHHHTT?S?HHHHHHHHHHHHHHHHHHHT?????TTSHHHHHHHHT?HHHHTSHHHHH-HHHHHHT???????--HHHHHHHHHHHHHHHHHHHHHHT??- 3BRJ|A PF05076.8_SUFU_seed 132 313 !Q:1,1|3,3|5,5|14,17|20,21|26,27|38,68|71,71|77,79|97,98|100,110|112,112|115,116|125,135|139,139|145,148|150,163|166,166|169,189|191,191|194,196|200,205|207,208|212,221|225,225|228,230|232,234|237,243|248,254|264,264|273,276|279,282|287,287|292,293|305,305|307,307|310,311 Q:0,0|2,2|4,4|6,13|18,19|22,25|28,37|69,70|72,76|80,96|99,99|111,111|113,114|117,124|136,138|140,144|149,149|164,165|167,168|190,190|192,193|197,199|206,206|209,211|222,224|226,227|231,231|235,236|244,247|255,263|265,272|277,278|283,286|288,291|294,304|306,306|308,309|312,312 T?S?S?SEEEEEEE??--BT--TTTB??EEEEEEESSS------------------------------?SS?SSSSS???TTTSEEEEEEEEEEEEE??T-----------T?SS??SHHHHHHH-----------HHH-HHHHH----H??---?--?----?TT?EE------------------???S?TT---SSS?-----S??EEE----------EEE?SS???E---EE-------TTEE-------EEEEEEEEE?HHHHHHHH----HS?---HHHH-HHHH--HHSGGGTTTTT?B?TT??S 3K5J|A PF05082.8_Rop-like_seed 32 68 !Q:0,3|32,32|67,67 Q:4,31|33,66 ????HHHHHHHHHHHHHHHHHHHHHHHHHHHS-TTTSGGGHHHHHHHHHHHHHHHHHHHHHHHHHHT? 2JS5|A PF05087.7_Rota_VP2_seed 3 902 !Q:0,122|132,141|143,146|151,154|162,162|165,167|173,177|198,199|202,203|208,211|217,220|222,222|236,237|239,239|249,251|266,267|281,287|296,296|302,302|307,309|311,314|317,317|319,327|330,330|335,335|355,360|362,362|375,377|380,381|387,387|390,392|411,412|414,415|417,418|421,421|436,436|441,441|463,463|467,471|475,475|485,486|499,500|505,506|510,512|517,517|523,524|540,541|582,583|585,591|594,594|596,597|609,610|612,617|654,654|658,658|673,674|679,679|693,696|720,721|727,727|730,730|732,736|742,742|745,745|748,749|752,754|764,765|776,777|780,780|784,787|789,790|810,810|813,813|815,819|821,824|830,831|837,841|844,845|848,852|854,855|869,870|872,873|875,875|879,881|884,885|891,891|894,895|899,901 Q:123,131|142,142|147,150|155,161|163,164|168,172|178,197|200,201|204,207|212,216|221,221|223,235|238,238|240,248|252,265|268,280|288,295|297,301|303,306|310,310|315,316|318,318|328,329|331,334|336,354|361,361|363,374|378,379|382,386|388,389|393,410|413,413|416,416|419,420|422,435|437,440|442,462|464,466|472,474|476,484|487,498|501,504|507,509|513,516|518,522|525,539|542,581|584,584|592,593|595,595|598,608|611,611|618,653|655,657|659,672|675,678|680,692|697,719|722,726|728,729|731,731|737,741|743,744|746,747|750,751|755,763|766,775|778,779|781,783|788,788|791,809|811,812|814,814|820,820|825,829|832,836|842,843|846,847|853,853|856,868|871,871|874,874|876,878|882,883|886,890|892,893|896,898 ?????????????????????????????----------?????????????????????------------???????????????????????????????????????????????????HHHHHHHHT??????????S????EEEE????EETTTEE?SS???EEEES?????SSHHHHHHHHHHHHHHHHHH??SS??SGGG????SSSSS????S?HHHHHHHHHHTTS??S?HHHHHHHHT???EEEGGGTEEEEEEE??HHHHHHHHHHHTT???????HHHHHHTS?TTTSS?TTEE???S????TT?B?????????TT?TTSS?THHHHHHHHHHHHHHHTTS??????S?HHHHHHHHHHHH???SS??SSTTS?TT???TTHHHHHHHHHHHHHHHT??B??B??SS?HHHHHHHHHHHHHS?STTB?HHHHHHHHHHHHHHTTSTTTT?TTS?????SSS?TTGGGTTTS??HHHHHHHHHHHT??EEEE??SSS???EEEE?TTTSS??HHHHHHHHHHHHHSS??SSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGG??S???????SS?B??BHHHHHHHHHS??S??????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT?TTS?SSSHHHHHHHTSTT??GGGS?STTHHHHHHHHTT????HHHHHHHHHHHHHHHHHHHSSSS??SEEEE?SS?B?????SSSSS?SB?SS??SS???BSTTHHHHT??SHHHHHHHHT??EE?BSS????B??SGGGGTTTGGGSGGGGGGG?SS?S?????B????TTTSS??HHHHH?????BS??EE?????B??HHHHEEEEEEESS??B??S?TTS???EE??GGGEE?TT??EES??? 4F5X|A PF05089.7_NAGLU_seed 30 400 !Q:3,4|15,16|32,33|37,38|54,55|64,65|68,68|77,78|80,80|83,86|109,109|115,116|118,118|121,121|129,129|132,133|136,138|143,148|151,152|156,156|159,160|164,165|183,184|186,187|192,193|199,201|204,206|208,238|254,254|257,257|261,261|265,273|279,279|286,286|288,292|296,296|308,311|314,323|329,331|337,339|343,344|347,349|364,367|369,369|376,377|379,381|383,383|396,396|399,399 Q:0,2|5,14|17,31|34,36|39,53|56,63|66,67|69,76|79,79|81,82|87,108|110,114|117,117|119,120|122,128|130,131|134,135|139,142|149,150|153,155|157,158|161,163|166,182|185,185|188,191|194,198|202,203|207,207|239,253|255,256|258,260|262,264|274,278|280,285|287,287|293,295|297,307|312,313|324,328|332,336|340,342|345,346|350,363|368,368|370,375|378,378|382,382|384,395|397,398 EEE??TTHHHHTTTT??HHHHHHHHHHHHHTT??EEE??TTHHHHHHHHHGGGT??HHHHHHHS??TT?HHHHHTTS??S-TT????TTHHHHHHHHHHHHHHHHHHHT?EEEEE??S?EE?TTHHHHS-TT??EE???EETT------EE??EEE?SS??TTS??HHHHHHHHHHHHHHHHH-?S??SEEE??TTTTS???TT---S?------------------------------HHHHHHHHHHHHHHH?TT?EEE-EEE---------BTTBS?HHHHTT?S----?GGG-EEEEETTTTTS?-??HH----------HHTTT-??EEEEE???STT??SS???HHHHHHHHHHHHHT---?S?EEEEEE??S???S?HHHHHHHHHGGG?SS? 2VCB|A PF05096.7_Glu_cyclase_2_seed 3 296 !Q:0,43|45,46|55,56|59,60|69,69|77,78|82,82|92,93|100,101|104,108|145,145|148,150|154,155|157,157|160,160|165,165|174,174|178,179|186,186|193,195|220,220|224,224|232,232|242,244|246,247|249,252|255,255|275,275|284,296 Q:44,44|47,54|57,58|61,68|70,76|79,81|83,91|94,99|102,103|109,144|146,147|151,153|156,156|158,159|161,164|166,173|175,177|180,185|187,192|196,219|221,223|225,231|233,241|245,245|248,248|253,254|256,274|276,283 -?--------------------------------------????B??EEEEEEEE??TT??EEEEEEET-TEEEEEE??TTS?EEEEEETTT??EEEEEE??TT?---?EEEEEEETTEEEEEESSSSEEEEEETTTTEEEEEEE?SS???EEE--E?SS?EEEE?SSSEEEEE?TTT??EEEEEE?EETTEE???EEEEEEETTEEEEEETTTTEEEEE?TTT?BEEEEEE?GGGSTTTTS???T--T----SS?EEEEEEETTTTEEEEEETT?SEEEEEEE??----??????- 3NOL|A PF05099.8_TerB_seed 153 185 !Q:1,3|5,5|8,9|13,13|25,34|44,47|54,55|59,60|80,81|99,99|113,114|118,127|147,150|152,152|170,170|173,184 Q:0,0|4,4|6,7|10,12|14,24|35,43|48,53|56,58|61,79|82,98|100,112|115,117|128,146|151,151|153,169|171,172 S-??S?SS??STH-HHHHHHHHTTT--------??STTHHHHHH----HHHHHH??SSS??SHHHHHHHHHHHHSGGGSS??HHHHHHHHHHHHHHTTT?HHHHHHHHHHHHH??SSS----------HHHHHHHHHHHHHHHTTTT----S?SSTHHHHHHHHHHHTTS?SS??--------?? 2JXU|A PF05103.8_DivIVA_seed 99 149 !Q:0,1|8,11|15,16|18,18|41,43|55,148 Q:2,7|12,14|17,17|19,40|44,54 ??HHHHTT????EET--T-EEEHHHHHHHHHHHHHHHHHHH---HHHHHHHHHHH??????---------------------------------------------------------------------------------------- 2WUJ|A PF05108.8_DUF690_seed 7 524 !Q:0,73|81,82|96,96|107,110|114,114|122,122|124,126|129,129|133,133|135,140|142,143|160,161|163,163|173,176|179,179|184,185|192,193|197,200|216,217|219,219|228,229|231,234|236,238|241,242|250,250|252,254|257,260|266,267|271,272|275,280|283,283|288,294|297,297|315,315|326,327|330,330|333,334|337,337|345,347|350,356|359,360|363,367|371,372|381,381|384,384|387,387|397,397|400,400|405,406|408,409|412,412|414,418|422,422|424,424|430,432|440,441|454,454|458,458|463,463|468,479|485,488|490,490|493,494|502,502|504,508|514,523 Q:74,80|83,95|97,106|111,113|115,121|123,123|127,128|130,132|134,134|141,141|144,159|162,162|164,172|177,178|180,183|186,191|194,196|201,215|218,218|220,227|230,230|235,235|239,240|243,249|251,251|255,256|261,265|268,270|273,274|281,282|284,287|295,296|298,314|316,325|328,329|331,332|335,336|338,344|348,349|357,358|361,362|368,370|373,380|382,383|385,386|388,396|398,399|401,404|407,407|410,411|413,413|419,421|423,423|425,429|433,439|442,453|455,457|459,462|464,467|480,484|489,489|491,492|495,501|503,503|509,513 -----------------------------------------------------????---------------??EEEETTT??EEEEETTEEEEES?HHHHHHHHTS????EEE?GGGGGGS?B???BS?TTS?S????-?S??SEEEEEEEEEESTTSS--S?EEEEEEEES????BT-TEEE??TTEEEE--EEE----TTEEEEEETTEEEEE??S?HHHHHHTT??T----T???EE??HHHHHHS?B???SS????TTTTS??SSS??TT?----?TT?EEEE-------EE-TTEEEEEEEETTEEEEE?HHHHHHHHHH??TT?SS??EE?HHHHTTS--?EE???????SS??EE??---TTT??EEEEEEEE?TT?SS?EEEEEEESS?SS?TGGG--G??EE?T-----TSS?E-EEESS?--EEEEEEE--ESSSEEEEEEEE?TTS?EEEE?SHHH------------HHHTT??--S?EE??HHHHTTS?B?????HHHHT??????---- 4KK7|A PF05109.8_Herpes_BLLF1_seed 3 908 !Q:0,7|16,17|21,22|24,25|33,35|38,38|41,42|59,60|63,64|67,67|69,69|73,73|77,78|80,80|85,85|88,88|92,93|97,97|106,107|111,111|113,117|121,122|134,134|138,138|153,165|167,167|180,180|189,189|192,192|196,197|202,203|205,206|209,213|218,219|223,224|227,227|233,234|238,239|242,243|250,250|252,252|255,257|260,262|270,274|278,278|290,290|293,294|297,297|299,299|308,312|314,315|317,319|325,327|336,336|342,343|346,346|348,351|353,354|358,358|360,360|366,367|369,370|373,374|376,378|381,382|384,392|398,398|402,402|408,411|414,414|418,419|423,423|426,427|436,442|447,451|456,907 Q:8,15|18,20|23,23|26,32|36,37|39,40|43,58|61,62|65,66|68,68|70,72|74,76|79,79|81,84|86,87|89,91|94,96|98,105|108,110|112,112|118,120|123,133|135,137|139,152|166,166|168,179|181,188|190,191|193,195|198,201|204,204|207,208|214,217|220,222|225,226|228,232|235,237|240,241|244,249|251,251|253,254|258,259|263,269|275,277|279,289|291,292|295,296|298,298|300,307|313,313|316,316|320,324|328,335|337,341|344,345|347,347|352,352|355,357|359,359|361,365|368,368|371,372|375,375|379,380|383,383|393,397|399,401|403,407|412,413|415,417|420,422|424,425|428,435|443,446|452,455 ????????SSEEEEEE??BSS??S??EEEEETS???TT?SS??EEEEEEEEEEETTEEE??EE??EE-E?TTT?SEE??S?EETS?SS?TTT??EEE?STTEEEEE??SSS?S?????GGG??EEEEEEEEEEE?TTS?EEEEEEEEEEEEEE?????????--??S?EEEEEEEEESSS?EEEEEEEE?SS?SSS??BEEE??B??TT?????BBSS??BSS??SS?EEEEB??SBS??SS??EEEEEE?S?SS???SS???EEEEEEE?????GGG?SSEEEEEEEES?SS??TT?S?EEEEEEEE?????S??S???EEEEE???SSSEEEEE?SSSSS?-TT?S????B??BSS?S?HHHHS??B??TT??S--?TT??S---------EEEEE?GGG?EEEEE????SS?EEE??EEE?TT??EEEEEEEE???????TTTT?????SSSS??????????????--------------------------------------------------------------------------------------?---------------------------------------------------------------------------------???--------------------??----------------------------------------???----------------------------------?----------------------------------------------------------------???----------------------------------------------------------------------------------------------?----- 2H6O|A PF05114.8_DUF692_seed 7 311 !Q:0,2|8,9|19,19|26,27|31,31|38,39|53,53|55,55|60,60|62,64|67,67|70,72|88,91|94,94|96,118|120,122|143,144|148,151|153,153|155,155|158,158|161,161|175,175|192,193|195,195|204,204|214,258|271,271|275,276|280,287 Q:3,7|10,18|20,25|28,30|32,37|40,52|54,54|56,59|61,61|65,66|68,69|73,87|92,93|95,95|119,119|123,142|145,147|152,152|154,154|156,157|159,160|162,174|176,191|194,194|196,203|205,213|259,270|272,274|277,279|288,310 ???SEEEE??GGGHHHHHH?SSSSSS??EEE?HHHHHT??HHHHHHHHHHTTT-S?EEEB?S???TT?SS???HHHHHHHHHHHHHTT????EE?S???????-???--------????B???HHHHHHHHHHHHHHHHHHTS??EEE????S?B?TT?SS?HHHHHHHHHHHHT?EEEEEHHHHHHHHHHH??S?HHHHHHHS?GGGEEEEEE?????????-???????????????????????????????????HHHHHHHHHHTT?SSB??EEE????????HHHHHHHHHHHHHHHHHHHHHHT 3BWW|A PF05115.9_PetL_seed 28 32 !Q:0,0|29,31 Q:1,28 ?HHHHHHHHHHHHHHHHHHHHHHHHHTTS??? 2ZT9|E PF05116.8_S6PP_seed 23 276 !Q:0,0|7,7|14,21|23,23|36,37|49,49|52,52|65,68|82,86|91,91|101,101|103,104|106,107|117,117|120,120|122,122|125,126|130,130|140,140|144,144|161,161|166,170|184,184|199,203|212,212|221,221|230,230|233,235|238,240|249,250|254,255|258,258|261,261|275,275 Q:1,6|8,13|22,22|24,35|38,48|50,51|53,64|69,81|87,90|92,100|102,102|105,105|108,116|118,119|121,121|123,124|127,129|131,139|141,143|145,160|162,165|171,183|185,198|204,211|213,220|222,229|231,232|236,237|241,248|251,253|256,257|259,260|262,274 ?SEEEEE?TBTTTB--------S?HHHHHHHHHHHT--TSGGGEEEEEE?SS?HHHHHHHHHHHT????SEEEETTTTEEEE-----TTEE?HHHHHHHHT-T??H--HHHHHHHHT?TT-E-EE??GGG?BTTBEEEEE?TTS?THHHHHHHHHHHTTTS?EEEE-----EETTTEEEEEETT?SHHHHHHHHHHHHT??---GGGEEEEE?SGGGHHHH-HSSSEEEE?TT-??HH---HHHHHHHH??TTE--EE?SS?THHHHHHHHHHTT? 4DWO|A PF05118.10_Asp_Arg_Hydrox_seed 11 181 !Q:16,17|19,22|26,27|30,31|34,34|39,39|52,52|60,60|70,70|76,88|91,91|99,99|108,109|111,111|115,119|128,130|144,146|149,149|154,154|158,158|164,164|168,168|178,178 Q:0,15|18,18|23,25|28,29|32,33|35,38|40,51|53,59|61,69|71,75|89,90|92,98|100,107|110,110|112,114|120,127|131,143|147,148|150,153|155,157|159,163|165,167|169,177|179,180 HHHHTHHHHHHHHHHH??T----TTT??EE??SS?EEES?EEEEEEEETTEE?HHHHHHS-HHHHHHHTT?HHHHT------------?TT?EEEEEEE?TTEEEEEE??S?TTE-----EEEEEEEE??-SSSEEEEETTEEE???BT?EEEE?TTS?EEEEE?SSS?EEEEEEEEE?TT 3RCQ|A PF05127.9_Helicase_RecD_seed 106 286 !Q:4,4|23,33|38,38|41,42|44,44|52,100|104,105|107,108|116,131|134,140|150,150|158,160|166,167|172,182|189,192|197,197|208,251|254,254|256,256|261,262|264,264|268,268|271,271|277,277|284,285 Q:0,3|5,22|34,37|39,40|43,43|45,51|101,103|106,106|109,115|132,133|141,149|151,157|161,165|168,171|183,188|193,196|198,207|252,253|255,255|257,260|263,263|265,267|269,270|272,276|278,283 EEEE?TTSSHHHHHHHHHHHSSS?----------EEEE?SS??S?HHHHHHH-------------------------------------------------GGG??B??HHHHHHS????------------SE-------EEEETGGGS?HHHHHHH---HTTSS--EEEE-----------EEEBSS----TTBB?HHHHHHHHHT--------------------------------------------ST-T?EEEE??S?SSS?TT?HHHHH-HHHHHT?? 1W36|D PF05129.8_Elf1_seed 37 105 !Q:0,24|27,34|38,39|42,42|48,51|55,60|72,75|78,78|82,84|87,88|103,104 Q:25,26|35,37|40,41|43,47|52,54|61,71|76,77|79,81|85,86|89,102 ?????????-?????----??????SS?----???TTT??SS?EEEEE----ETT------TTEEEEEESSS--??EE-EEE-??SS??TTHHHHHHHHHHHH?? 1WII|A PF05130.7_FlgN_seed 154 207 !Q:0,18|27,28|37,40|56,60|62,62|71,73|86,87|99,112|124,128|130,130|143,146|153,155|167,170|183,206 Q:19,26|29,36|41,55|61,61|63,70|74,85|88,98|113,123|129,129|131,142|147,152|156,166|171,182 ?---------------???SHHHHHHH--HHHHHHHH----HHHHHHHHHHHHHTT--?-?H-HHHHHHHH---HHHHHHHHHHHH--HHHHHHHHHTT??------------SSHHHHHHHHT-----T?TTHHHHHHHHHH----HHHHHH---HHHHHHHHHHH????TTHHHHHHHHHH??????-------??????????? 3OPC|A PF05133.9_Phage_prot_Gp6_seed 56 670 !Q:0,4|15,21|34,38|43,45|47,51|54,54|57,58|62,62|66,72|90,91|95,95|97,102|104,109|121,124|151,159|163,168|174,175|177,177|184,308|310,310|312,312|318,318|322,329|332,332|347,348|360,360|362,362|368,389|393,419|421,421|438,454|464,474|495,498|500,502|506,510|553,557|562,565|569,573|575,575|579,586|595,598|604,606|611,611|614,615|621,621|623,631|633,639|641,643|650,651|660,669 Q:5,14|22,33|39,42|46,46|52,53|55,56|59,61|63,65|73,89|92,94|96,96|103,103|110,120|125,150|160,162|169,173|176,176|178,183|309,309|311,311|313,317|319,321|330,331|333,346|349,359|361,361|363,367|390,392|420,420|422,437|455,463|475,494|499,499|503,505|511,552|558,561|566,568|574,574|576,578|587,594|599,603|607,610|612,613|616,620|622,622|632,632|640,640|644,649|652,659 ?????HHHHHHHHHH???----HHHHHHHHHHTT---??GGGG???E-----EE?TT??EEE?TTS???????THHHHHHHHHHHHHTSS??EEE?S-----?H------HHHHHHHHHSS----SHHHHHHHHHHHHHHHHSEEEEEEEE?--------TTS?-----EEEEE--E?TTTEEE?????????????????????????????---------------------------????????----------?????????---?????????????????????????------------??S?S?EEEES-SSS?-----??GG-GGTHHHHHHHHHHH--HHHHHHHHHTT-S?EEEEE----------------------EES?--------------------------S?HHHHHHHHHHSSEEEE-----------------EEEEEEEEE?------????HHHHHHHHHHHHHHHHHHTT????S-??SST-----TTTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----HHTS????HHH-----H?EEE????????HHHHHHHH----HHHHH---HTSS?HH--HHHHH?T---------T?------S--?HHHHHH--HHHHHHTT?????????? 2JES|A PF05134.8_T2SL_seed 19 321 !Q:5,5|7,7|15,18|33,36|61,61|71,80|84,84|86,94|96,96|104,120|123,124|147,147|160,164|176,225|231,231|235,235|243,243|260,261|267,274|277,287|289,291|293,293|305,311|313,314|318,320 Q:0,4|6,6|8,14|19,32|37,60|62,70|81,83|85,85|95,95|97,103|121,122|125,146|148,159|165,175|226,230|232,234|236,242|244,259|262,266|275,276|288,288|292,292|294,304|312,312|315,317 EEEEE?S?TTSEEEE----EEEETTTTEEEEEE----EEETGGGGGGGHHHHTTSEEEEEE?GGGSEEEEE??????????STT?S?????????S?TTEEEEE?-------------???SS-?EEEEEEEHHHHHHHHHHSTTTT?EEEEEEEGGGGS??--?SSSEEEEEETT--------------------------------------------------EEEEE?SSS?EEEEETT?HHHHTTSSTTEETTEE??EEESS????????SS?-------???B???S?HHHHHHHHHHT---????S??GGG??? 1W97|L PF05135.8_Phage_connect_1_seed 81 160 !Q:0,33|41,42|49,50|59,62|74,74|76,76|78,93|97,97|99,101|114,114|119,121|126,127|129,129|132,132|137,138|142,142|144,144|146,147|159,159 Q:34,40|43,48|51,58|63,73|75,75|77,77|94,96|98,98|102,113|115,118|122,125|128,128|130,131|133,136|139,141|143,143|145,145|148,158 ---------------------------------?THHHHTT--TTTTTH--HHHHHHHH----HHHHHHHTTTT?S?B---------------?TTS?B???HHHHHHHHHHHH-HHHH---HHTT--S?SS?SSSS??TTT?S?T--TGGGTSSTTTT? 3JVO|A PF05138.7_PaaA_PaaC_seed 117 407 !Q:0,25|39,40|42,42|46,48|77,79|83,83|113,135|137,144|146,157|171,175|181,194|218,218|221,221|253,253|256,256|276,276|280,280|282,282|286,301|310,310|313,313|331,331|335,337|339,347|350,351|355,355|358,361|364,364|368,374|385,385|404,404 Q:26,38|41,41|43,45|49,76|80,82|84,112|136,136|145,145|158,170|176,180|195,217|219,220|222,252|254,255|257,275|277,279|281,281|283,285|302,309|311,312|314,330|332,334|338,338|348,349|352,354|356,357|362,363|365,367|375,384|386,403|405,406 ???????????--------------?HHHHHHHHHHHTT??B?TTS???HHHHHHHHHHHHHHHHHHHHTHHHHHTT---GGG?SSHHHHHHHHHHHHHHHHHHHHHHHHHHT-----------------------T--------T----------??HHHHHHHHHHTSS--???GGGGS???-----------SSHHHHHHHHHHHHHHHHHHHHT-TT?SBHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-TS?HHHHHHHHHHHHHHHHHHH-HTT?S?TTS??------------??HHHHHTTS?SS?HHHHHHHHHHHHHHHHH-HTT???S---?-----TT-?EEE-TT----TT-EEE?--????HHHHHHHHTT?SSSHHHHHHHHHHHHHHT-HH 3PF7|A PF05139.9_Erythro_esteras_seed 73 457 !Q:20,22|24,42|46,62|65,65|69,70|87,87|90,96|98,102|109,109|111,116|126,128|134,134|139,145|159,160|162,162|169,177|179,179|199,214|233,239|248,254|274,283|285,285|290,291|296,296|299,299|301,301|305,315|318,318|331,331|348,361|366,369|382,382|391,398|400,401|409,410|414,415|420,423|425,437|447,447 Q:0,19|23,23|43,45|63,64|66,68|71,86|88,89|97,97|103,108|110,110|117,125|129,133|135,138|146,158|161,161|163,168|178,178|180,198|215,232|240,247|255,273|284,284|286,289|292,295|297,298|300,300|302,304|316,317|319,330|332,347|362,365|370,381|383,390|399,399|402,408|411,413|416,419|424,424|438,446|448,456 EEEEEEEHHHHHHHHHHHHH?-?S------------------?GGG-----------------TS?TTS-?BHHHHHHHHHHHHHHH?TT-----??S?---?EEEEEE?S---???HHHHHHHHH---HHHHH?TTSH-------HHHHHHHHTGGGS-?S?HHHHTT---------S?HHHHHHHHHHHHHHHHHTS?--?????????????HHHHHHHHHHHHHHHHHT-------SSSSSHHH-------HHHHHHHHHHHHHHHHHHH--?-------S?EEEE??HHHH?SS?S?TTT----------?SS?HHHHHHHHHGGG-EEEEEEEEEEEEEEES???---????????EEEE????TTSHHHHHHHSS?SEEEEEGG--------G??HHHHHHH--HSE--EEEE???-S??????-----??EEEEEHHHH?SEEEEEEEE 3B55|A PF05141.7_DIT1_PvcA_seed 33 343 !Q:9,10|16,22|24,27|29,29|34,34|37,38|62,62|68,70|80,81|101,111|114,114|118,119|123,147|154,155|158,158|171,173|178,180|187,189|208,211|213,214|217,218|220,220|260,262|271,271|274,294|296,296|299,303|312,317|325,325|332,332|335,335 Q:0,8|11,15|23,23|28,28|30,33|35,36|39,61|63,67|71,79|82,100|112,113|115,117|120,122|148,153|156,157|159,170|174,177|181,186|190,207|212,212|215,216|219,219|221,259|263,270|272,273|295,295|297,298|304,311|318,324|326,331|333,334|336,342 HHHHHHHTT??EEEEE???????S---?T-TTSS?SS??HHHHHHHHHHHHHHHHHHHHSTT?EEEEE???HHHHGGGTT??HHHHHHHHHHHHHHHHHHT----------?SS-EEE??GGG?------------------------GGGGGG--TT?HHHHHHHHHHHH???HHHH---HHHHTT---SHHHHHHHHHHHHHHHHH----H??TT??S?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSEEEESS???TTSSEEEB?SS-------------------??S?TT---??GGGSEEEE-?----SSSEEEE?HHHHHH-TT?EEEEETT 3E59|A PF05147.8_LANC_like_seed 47 471 !Q:0,0|3,5|22,23|27,29|32,34|39,39|51,52|54,69|90,90|95,95|109,109|112,128|136,137|149,152|156,156|159,160|162,165|187,190|197,197|199,202|204,208|212,214|216,216|231,232|236,245|247,249|267,268|270,270|272,272|274,279|284,301|315,323|331,333|347,347|351,352|354,354|356,358|362,362|364,364|384,385|388,389|398,400|411,430|445,446|458,465|469,470 Q:1,2|6,21|24,26|30,31|35,38|40,50|53,53|70,89|91,94|96,108|110,111|129,135|138,148|153,155|157,158|161,161|166,186|191,196|198,198|203,203|209,211|215,215|217,230|233,235|246,246|250,266|269,269|271,271|273,273|280,283|302,314|324,330|334,346|348,350|353,353|355,355|359,361|363,363|365,383|386,387|390,397|401,410|431,444|447,457|466,468 ?TT???SSSSHHHHHHHHHHHH--HHH??-HH---HHHH-HHHHHHHHHTT??S?------------???TTTSTHHHHHHHHHHHHHTT?HHHH-HHHHHHHHGGGGG?TT??---------------SSTTTSH--HHHHHHHHHHH----HHH-SS??S?---HHHHHHHHHHHHHHHHHHHHH----TTTTTT?S????B-----TTB?--B?STTTSHHHHHHHHT-?GGG-------???H---HHHHHTHHHHHHHHHHT??T-T-S?---??SBTT??---??--------???SSSSSHHHHHHHH---------HHHHHHH-??HHHHHHHHHHHHH-HHH--H?S---BTT?S?STTSHHHHHHHHHHHHHHH??HH--HHHHHHHH---HHHHTTTTSS--------------?????-SSTTSTTTSHHHHH--HHHHHHTSGGG???-----TTT?? 2G0D|A PF05148.10_Methyltransf_8_seed 4 235 !Q:0,6|25,25|36,36|57,57|68,75|78,78|82,82|88,88|91,91|95,96|99,100|102,104|112,112|121,121|123,123|126,126|128,129|132,132|141,143|146,146|169,169|173,173|175,177|197,198|202,202|210,210|213,213|216,216|219,221|225,234 Q:7,24|26,35|37,56|58,67|76,77|79,81|83,87|89,90|92,94|97,98|101,101|105,111|113,120|122,122|124,125|127,127|130,131|133,140|144,145|147,168|170,172|174,174|178,196|199,201|203,209|211,212|214,215|217,218|222,224 -----??HHHHHHHHHHHHHHHHHS?HHHHHHHHHH?HHHHHHHHHHHHHHHTTSSS?HHHHHHHHHH--------TS?TTS?EEEET?TT?HHH--HH??S?--EEEEESS?SSTTEEES?T-TS?S??TT?EEEEEEES???SS?HHHHHHHHHHHEEEEEEEEEEE?GGG?S--?HHHHHHHHHHTTEEEEEEE??STT?EEEEEEE?SS?SS?TT???GGG?????????? 2YR0|A PF05151.7_PsbM_seed 19 31 !Q:0,3 Q:4,30 ????TTHHHHHHHHTTHHHHHHHHHHHHHHT 3PRR|M PF05153.10_DUF706_seed 21 267 !Q:3,3|20,21|34,35|37,38|40,40|43,43|54,56|59,59|62,63|65,65|81,81|84,86|105,106|108,110|112,113|120,122|127,129|139,139|142,142|157,158|161,162|167,167|169,169|185,188|200,200|208,209|213,214|235,236|239,241|258,258|260,263|266,266 Q:0,2|4,19|22,33|36,36|39,39|41,42|44,53|57,58|60,61|64,64|66,80|82,83|87,104|107,107|111,111|114,119|123,126|130,138|140,141|143,156|159,160|163,166|168,168|170,184|189,199|201,207|210,212|215,234|237,238|242,257|259,259|264,265 SSS?SSHHHHHHHHHHHHHH??HHHHHHHHHHHT--T??S?EE?HHHHHHHGGG???SS?TT??S?HHHHHHHHHHHHHHH?TT?--HHHHHHHHHTTGGGGGGG--G---T??GGGTSS???BSSS???TTSTTTTTS?TT?GGGGSTTTSSSSTT??TT??GGGS?B?SSHHHHHHHHHHHTT????HHHHHHHHHTT?HHHHTSS??TTT??HHHHHHHHHHHHHHHHHHHT??SS???HHHHHHHHHHHHHHHS?S---?EE? 2HUO|A PF05157.10_T2SE_Nter_seed 110 260 !Q:3,3|5,10|12,12|14,56|58,63|66,94|103,131|134,135|137,146|151,151|154,165|167,168|182,183|186,186|188,193|199,200|204,204|206,208|210,211|222,222|224,224|226,227|230,231|235,236|242,242|249,259 Q:0,2|4,4|11,11|13,13|57,57|64,65|95,102|132,133|136,136|147,150|152,153|166,166|169,181|184,185|187,187|194,198|201,203|205,205|209,209|212,221|223,223|225,225|228,229|232,234|237,241|243,248 HHH-T------T?S?------------------------------------------H------HH-----------------------------HHHHHHHH-----------------------------HT??B--------??GGGS?SS????????---?S??HHHHHHHTEEEEE--EE-T------TEEEE--EES?T---T?-HHHHHHHHHH-H?S-?EE--EEE??HHHHH-HHHHHH----??----- 2D28|C PF05160.8_DSS1_SEM1_seed 28 77 !Q:0,8|14,16|19,21|23,23|25,50|52,52|56,63|68,68|76,76 Q:9,13|17,18|22,22|24,24|51,51|53,55|64,67|69,75 ?????--??GGGEE--?TT???S?S???--??????????---------??B?SSS?????-??TTTS?TTTHHHH? 1MIU|B PF05161.8_MOFRL_seed 14 126 !Q:8,9|11,14|16,23|38,41|43,43|47,49|59,60|62,65|69,70|82,82|88,90|99,99|109,112|115,119|121,124 Q:0,7|10,10|15,15|24,37|42,42|44,46|50,58|61,61|66,68|71,81|83,87|91,98|100,108|113,114|120,120|125,125 SEEEEEEE??B????S--?-????HHHHHHHHHHHHTT----T?TTE---EEEEEETTS??S----SSS??EEEEETTHHHH-HHHTT??-HHHHHHTT?HHHHHHHTT?---EE?????S????E 2B8N|A PF05162.8_Ribosomal_L41_seed 3 25 !Q:0,2|23,24 Q:3,22 ???SHHHHHHHHHHHHHHHTTTS?? 3J39|n PF05163.7_DinB_seed 14 207 !Q:0,14|34,35|41,45|51,52|74,84|92,100|119,120|122,124|132,139|142,142|172,177|179,202|204,206 Q:15,33|36,40|46,50|53,73|85,91|101,118|121,121|125,131|140,141|143,171|178,178|203,203 ?????----------HHHHHHHHHHHHHHHHHTT??TTSTT---??SSTTS??HHHHHHHHHHHHHHHHHHHHH-----------SSSGGGT?????????HHHHHHHHHHHHHHHHHT??H---HHHHSEE--??????SS?EEHHHHHHHHHHHHHHHHHHHHHHHHHTT??????S------------------------S??? 2QE9|A PF05164.8_ZapA_seed 162 222 !Q:0,0|3,6|8,8|18,20|40,40|46,47|49,50|52,52|61,62|68,74|80,86|88,91|97,100|106,173|179,184|190,217 Q:1,2|7,7|9,17|21,39|41,45|48,48|51,51|53,60|63,67|75,79|87,87|92,96|101,105|174,178|185,189|218,221 ?EE----E-EETTEEEEE???TTTHHHHHHHHHHHHHHHH-HHHTT--T?-S?SHHHHHHH--HHHHH-------HHHHH-------H----HHHHH----HHHHH--------------------------------------------------------------------HHHHH------HHHHH----------------------------HHHH 1T3U|A PF05165.7_GGDN_seed 4 261 !Q:0,0|20,22|46,46|50,50|60,60|63,64|82,82|108,109|112,112|115,118|124,129|132,133|153,153|173,173|178,180|192,192|195,196|212,219|246,247|250,250|260,260 Q:1,19|23,45|47,49|51,59|61,62|65,81|83,107|110,111|113,114|119,123|130,131|134,152|154,172|174,177|181,191|193,194|197,211|220,245|248,249|251,259 ?EEEEEEEETTHHHHHHSSS???HHHHHHHHHHHHHHHHHHHHTTT?EEE?TTSSEEEEE?TT??HHHHHHHHHHHHHHSSS?EEEEEEEESSHHHHHHHHHHHHHHH??TT?TT????EEESS??---?SS??EEEEEEEETTHHHHTTTTS?HHHHHHHHHHHHHHHHHHH-HTTT???EEEETTEEEEE?TT??HHHHHHHHHHHHHHH??-----?EEEEEEEESSHHHHHHHHHHHHHHHH--TT?SSSSEEEEE? 2QV6|A PF05166.8_YcgL_seed 61 84 !Q:11,11|18,27|30,32|35,35|43,43|52,52|56,59|63,63|80,83 Q:0,10|12,17|28,29|33,34|36,42|44,51|53,55|60,62|64,79 EEEEEETTSSS?EEEESS----------SS???SS?HHHHHHH?SEEEEEEE?SSS????SSS?HHHHHHHHHHTSEEEE???? 2H7A|A PF05167.7_DUF711_seed 53 484 !Q:0,2|18,20|29,30|34,35|51,51|65,68|74,75|85,85|92,92|95,97|99,106|122,122|127,127|133,133|136,138|155,155|164,164|190,190|192,195|207,208|210,214|216,217|219,225|229,229|238,239|251,252|254,254|256,274|281,281|308,310|316,328|338,338|365,381|392,394|405,410|415,416|419,420|440,441|449,450|452,453|456,469|471,475|477,478 Q:3,17|21,28|31,33|36,50|52,64|69,73|76,84|86,91|93,94|98,98|107,121|123,126|128,132|134,135|139,154|156,163|165,189|191,191|196,206|209,209|215,215|218,218|226,228|230,237|240,250|253,253|255,255|275,280|282,307|311,315|329,337|339,364|382,391|395,404|411,414|417,418|421,439|442,448|451,451|454,455|470,470|476,476|479,483 ?--SHHHHHHHHHHHHHS???EEEEEEEE??GGG??SSHHHHHHHHHHHHH-HHTTTHHHHHHHH----HHHHT??EEEEEEEES?HHHHHH-TS??-S??------HHHHHHHHHHHHHHT?SEEE-EEEEE?TT???TTHHHHHHHHHHHHHS?SSEEEEEE?EETTTEEEHHHHHHHHHHHHHHHTT?S----SGGGGEEEEES??T-----T??S???????TTS?SEEEEEEE??HHHHHHHHHTT--T-T?----?-------------HHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHTS---EEEEE?????????????HHHHHHHHH?SSTTSTTHHHHHHHHHHHHHHHHHTT?????????????????HHHHHHHHTT???HHHHHHHTTS??????EEEE?-TT??HHHHHHHHHHHHHHHHHHT??EEEEEEE?-S-?TT????????????-?B?????S??HHHHH 2HA9|A PF05168.9_HEPN_seed 92 158 !Q:20,20|23,25|48,49|52,57|60,60|65,65|67,68|70,83|91,97|105,106|111,114|119,120|124,125|139,142|147,147|149,154 Q:0,19|21,22|26,47|50,51|58,59|61,64|66,66|69,69|84,90|98,104|107,110|115,118|121,123|126,138|143,146|148,148|155,157 HHHHHHHHHHHHHHHHHHHH-TT--?HHHHHHHHHHHHHHHHHHHHHH--TT??--??SS?HHHH?S--S?------------?HHHHHHH-------HHHHTSS??SSTT????SSSG--GGG??HHHHHHHHHHHHH----HHHH-H------HHH 1UFB|A PF05171.7_HemS_seed 108 185 !Q:1,2|11,11|13,18|20,22|28,28|30,30|33,41|54,55|72,77|82,86|88,90|92,95|101,101|103,105|107,108|118,119|127,134|137,141|149,149|153,153|161,163|167,170|172,173|181,182 Q:0,0|3,10|12,12|19,19|23,27|29,29|31,32|42,53|56,71|78,81|87,87|91,91|96,100|102,102|106,106|109,117|120,126|135,136|142,148|150,152|154,160|164,166|171,171|174,180|183,184 T??HHHHHHHH?T------T---TEEEE?T-TH---------HHHHHHHHHHHT??EEEEEEETTEEEEEEE??--??EEEE-----T---T----EEEEE?S---S--EEEEEEGGG??EEEEEEE??------TT-?--?EEEEEEE?TTS?EEEEEEE???TTS-???H--HHHHHHH--SS 3FM2|A PF05172.8_Nup35_RRM_seed 7 143 !Q:0,3|9,13|18,20|36,36|42,91|93,93|118,118|126,126|131,135|140,142 Q:4,8|14,17|21,35|37,41|92,92|94,117|119,125|127,130|136,139 ????GGGGE-----EEEE???GGGHHHHHHHHHTTS?EEEEE--------------------------------------------------E?SSSSEEEEEESSHHHHHHHHTTTT?EETTTEE?EEEE?--??HHHH??? 3P3D|A PF05173.9_DapB_C_seed 189 184 !Q:18,20|22,22|31,31|34,35|39,39|54,75|77,78|80,80|87,89|91,96|98,100|103,104|112,112|115,116|125,125|137,138|141,142|156,159|161,163|165,168|170,170|173,175|178,178 Q:0,17|21,21|23,30|32,33|36,38|40,53|76,76|79,79|81,86|90,90|97,97|101,102|105,111|113,114|117,124|126,136|139,140|143,155|160,160|164,164|169,169|171,172|176,177|179,183 HHHHHHHHHHHHHHHTSS---S?EEEEEEEE?TT??SSS?HHHHHHHHHHHHTT----------------------T??H-HHHEEE???S---???S?-?TT?-EEEEEEE?TT??EEEEEEEE?SSEEEEEEEEE??TH--HHHHHHHHHHHHH----H---T-?--S-SE---EE?HHHHT 1YL6|A PF05175.9_MTS_seed 34 200 !Q:6,6|9,9|15,16|27,27|30,33|36,41|45,45|58,58|61,61|63,64|86,92|97,97|103,106|108,108|115,132|136,136|174,176|183,186|192,192 Q:0,5|7,8|10,14|17,26|28,29|34,35|42,44|46,57|59,60|62,62|65,85|93,96|98,102|107,107|109,114|133,135|137,173|177,182|187,191|193,199 TEEEEE?TT?TTSSS??HHHHHHHHHS?TT--??SB----??BTT?TTSHHHHHHHHH?TT?B-?EEEESBHHHHHHHHHHHHHTT??----?EEEE?STTTT??--S?EEEEEE???-------------??SSS-HHHHHHHHHHHHHHGGGEEEEEEEEEEEETTSSHHHH---HHHHHS--??EEEEE?SSEEEEE 1VQ1|A PF05179.9_CDC73_seed 6 323 !Q:0,149|151,152|156,159|162,162|165,165|176,185|190,192|202,203|209,216|228,229|242,243|245,245|255,259|279,283|297,297|300,301 Q:150,150|153,155|160,161|163,164|166,175|186,189|193,201|204,208|217,227|230,241|244,244|246,254|260,278|284,296|298,299|302,322 --------------------------------------------------------------------------------???????----------------------------------------------------------?????S??EEE????TT?SS?TTTHHHHHHH?????-----GGGS???TTSEEEEEE??TTSSS-------?EEEEEESSSTT??SGGGGGGEEEEE??S?GGGGTTSSS---?-SHHHHHHHSEEEEEEETTS--???HHHHHSSEEEEEE?SS??TTHHHHHHHHHHHHHHHHHHT 4DM4|A PF05180.7_zf-DNL_seed 36 82 !Q:7,14|39,39|43,44|49,50|53,53|57,57|59,60|62,69|78,81 Q:0,6|15,38|40,42|45,48|51,52|54,56|58,58|61,61|70,77 EEEEEEE--------TTTTEEEEEEEEHHHHHTSEEEEE?TTT??EEES??SS?SGG-G--S??-----?HHHHHHHH???? 2E2Z|A PF05181.7_XPA_C_seed 16 53 !Q:3,4|15,17|27,29|32,35|40,40|44,45|48,48 Q:0,2|5,14|18,26|30,31|36,39|41,43|46,47|49,52 TTS??EEHHHHHHHS???SSTTTTSSS???EE????SSSS?TTS??EE?HHHH 1XPA|A PF05183.7_RdRP_seed 94 1332 !Q:5,7|12,12|19,35|37,38|42,46|54,54|57,59|63,63|72,72|76,77|86,86|102,147|161,161|163,180|182,184|193,193|195,195|199,206|212,214|221,225|233,233|236,237|241,245|251,262|264,264|267,321|323,323|328,339|346,348|352,352|360,362|368,445|448,449|454,455|459,476|479,479|486,486|488,492|495,496|498,521|525,525|527,527|531,531|533,549|557,577|583,606|608,628|641,644|671,672|678,680|692,693|701,702|705,706|710,750|768,777|802,806|808,809|811,812|819,820|825,825|828,844|846,853|855,863|873,912|925,925|933,939|942,943|951,952|956,975|978,989|993,999|1005,1005|1007,1011|1014,1046|1048,1048|1056,1059|1061,1061|1064,1064|1068,1070|1073,1081|1085,1086|1091,1101|1104,1116|1121,1123|1155,1156|1170,1177|1182,1196|1218,1218|1223,1229|1239,1245|1249,1250|1253,1257|1262,1283|1286,1287|1292,1311 Q:0,4|8,11|13,18|36,36|39,41|47,53|55,56|60,62|64,71|73,75|78,85|87,101|148,160|162,162|181,181|185,192|194,194|196,198|207,211|215,220|226,232|234,235|238,240|246,250|263,263|265,266|322,322|324,327|340,345|349,351|353,359|363,367|446,447|450,453|456,458|477,478|480,485|487,487|493,494|497,497|522,524|526,526|528,530|532,532|550,556|578,582|607,607|629,640|645,670|673,677|681,691|694,700|703,704|707,709|751,767|778,801|807,807|810,810|813,818|821,824|826,827|845,845|854,854|864,872|913,924|926,932|940,941|944,950|953,955|976,977|990,992|1000,1004|1006,1006|1012,1013|1047,1047|1049,1055|1060,1060|1062,1063|1065,1067|1071,1072|1082,1084|1087,1090|1102,1103|1117,1120|1124,1154|1157,1169|1178,1181|1197,1217|1219,1222|1230,1238|1246,1248|1251,1252|1258,1261|1284,1285|1288,1291|1312,1331 EEEEE???EEEE?BHHHHH-----------------H-?GGG-----EEEEEEE?TT???SSS?TTSSSSSS?HHH--HHHHHHSS?EEETTEEEEEEEEEE???--------?????????-----------------?????????EEEEEEEEEEETT?B??????????????????B???HHHHHHHH-H?GGG?-------TTSBH---HHHHHT-----THHHHSB?EE--EEE---??GGGEE------------E?SS??-----------------------------------------------------B?TTSS??----------BSSTTE---EEE?HHHHHHH---HHHHT-----------------------------------------------------------------------------?SS??SEEE--EEE------------------TT-EEEEEE-E----?TT??S----???----------------?EEE?T-TTB?S------------?????SGGGSEE---------------------EEEEE??----------------??????B?--------------------TTTHHHHHHTBS----SHHHHHHHHHHHHHHHHHHHHHHHHH--HTTSH---HHHHHHHHHHS??HHHHHHH--TS??EET-----------------------------------------TEESSHHHHHHHHHHTT??--------TTTBHHHHHHHHHHHHHHHHHHHH-----H??B??SSEEEE--EEEE?TT-----------------S?-----??T---------TEEEEEEEE----------------------------------------EEEETTEEEEEE?SEEEEEE------?SS??SGGGEEE--EEE-------------???----GG------------GTT-?----?SEEEE?S----?SS---------------------------------S?HHHHTTT--??S-SS?EEE---EE-------??HHH--HHTB???????????TT-------------TSEE???BHHHHHTTSSHHHHHHHHHHHHHHHHHHHTS??HHHHHHHHHHHHH--------HHHT--------------?SSSHHHHHHHHHHHHHTTHHH-HTEE??-----HHHHHHHHH-------HHS??SS?????GGGS----------------------SS??SSSS------------------??SHHHHHHHTTHHHHHHHHHS 2J7N|A PF05184.10_SapB_1_seed 161 43 !Q:0,1|18,18|20,20|23,24|35,35|38,38|42,42 Q:2,17|19,19|21,22|25,34|36,37|39,41 ??HHHHHHHHHHHHHHHH-H-TT??HHHHHHHHHH-HT-TSS? 2R0R|A PF05185.11_PRMT5_seed 35 811 !Q:16,16|19,20|29,32|35,38|40,43|53,53|64,64|67,69|72,72|74,74|77,78|90,90|94,94|100,155|157,159|165,165|172,175|184,190|192,201|208,208|211,211|214,215|219,220|225,227|237,237|257,257|264,287|296,296|314,324|334,334|343,343|346,346|351,353|355,357|361,361|368,368|372,374|377,400|406,409|417,417|428,432|438,438|444,444|450,468|474,474|481,491|496,497|500,526|528,528|536,536|539,539|541,542|544,544|547,547|549,579|589,590|592,592|594,622|624,629|638,640|642,645|650,675|689,696|701,701|705,746|748,752|755,757|759,761|773,773|776,785|796,798 Q:0,15|17,18|21,28|33,34|39,39|44,52|54,63|65,66|70,71|73,73|75,76|79,89|91,93|95,99|156,156|160,164|166,171|176,183|191,191|202,207|209,210|212,213|216,218|221,224|228,236|238,256|258,263|288,295|297,313|325,333|335,342|344,345|347,350|354,354|358,360|362,367|369,371|375,376|401,405|410,416|418,427|433,437|439,443|445,449|469,473|475,480|492,495|498,499|527,527|529,535|537,538|540,540|543,543|545,546|548,548|580,588|591,591|593,593|623,623|630,637|641,641|646,649|676,688|697,700|702,704|747,747|753,754|758,758|762,772|774,775|786,795|799,810 GGGHHHHHHHHHHHHT-TT?-TTEEEEEE??--SS?-??H----HHHHTTTTS?EEEEEEEGGG?EE?--TT-S?EE??HHHHHHHHHHH-HTT?EEEEE--------------------------------------------------------S-??SSGGG?STHHHH----HHHHHHHS-------S?------???HHHHHS-TT?BT??BEE??TTTS???HHHHHHHTT?HHHHHHHHHHHHHHHHHHS?GGGTTT-----------------------?EEEEEEES?TTSHHHHHHHHHHHHTT--?--------EEEEEEEES?HHHHHHHH-HH-HHHT---T---GGG-EEEEES?TTT???SS-----------------------?EEEEE????BTTBGGG?HHHHHHHHGG-----GEEEE-EEEES?EEEEE-------------------EEEEE?HHHHHH-----------HHTT??TT---------------------------S?TTGGGGS?EE?B??S?EE?S??-----------------------------EEEEEEESS??S-T-----------------------------T--????EEEEEEEE?-?S---?EEEE--------------------------EEEEEEEEEEETT--------EEEE?SGG------------------------------------------G---??TT-??S???EEEEEEEEEEE?TT?---------EEEEEEEEEE?--SSEEEEEEEEEE 2Y1X|A PF05186.8_Dpy-30_seed 14 42 !Q:0,0|24,25|27,27 Q:1,23|26,26|28,41 ?HHHHHHTTTHHHHHHHHHHHHHH??S?HHHHHHHHHHHHGG 3G36|A PF05187.8_ETF_QO_seed 73 129 !Q:13,14|19,22|24,27|29,36|38,38|42,45|50,63|68,69|79,79|81,82|86,87|93,96|110,111|117,117|120,121|127,127 Q:0,12|15,18|23,23|28,28|37,37|39,41|46,49|64,67|70,78|80,80|83,85|88,92|97,109|112,116|118,119|122,126|128,128 THHHHHHHHHHHT--TTTT----T??--S?-???-??S?GGG????GGGS?-????????----SSSS??HHHHHHTTT?B??SSS??SEEES----STTHHHHTHHHHH??THHHH?TT??EEEEE?S 2GMH|A PF05188.12_MutS_II_seed 47 213 !Q:0,1|5,7|13,18|22,22|44,44|46,47|50,50|60,62|64,65|73,75|80,85|96,96|100,101|107,111|113,116|119,119|125,128|130,131|137,138|141,167|173,173|179,183|186,191|198,198|200,205|210,210 Q:2,4|8,12|19,21|23,43|45,45|48,49|51,59|63,63|66,72|76,79|86,95|97,99|102,106|112,112|117,118|120,124|129,129|132,136|139,140|168,172|174,178|184,185|192,197|199,199|206,209|211,212 ??EEE---EEEES??????TTT?EEEEEEEEETTTTEEEEEEEE-E?-TT?HHHHHHHHH---H??SEEEEES???HHHH------HHHHHHHHHS?TTT??EEEEE----?T----TT-TSHHH----H--HHHHH--HH?------????????????????????HHHHH-HHHHH-----HH------HHTTTT?G------GGGG?GG 2O8E|A PF05189.8_RTC_insert_seed 99 152 !Q:0,0|2,8|10,13|19,20|26,27|41,41|44,48|51,51|56,57|62,74|76,76|81,81|83,83|85,85|95,95|98,98|100,100|108,125|127,127|130,131|148,148|151,151 Q:1,1|9,9|14,18|21,25|28,40|42,43|49,50|52,55|58,61|75,75|77,80|82,82|84,84|86,94|96,97|99,99|101,107|126,126|128,129|132,147|149,150 ?S?????--E----EEEEE--EEESS-?THHHHHHHHHHHH-HS-----TT?SSEE??EEEE-------------E?SGGG?S-S?EEEEEEEEE?TT-S?EEEEEEE------------------E?TT??HHHHHHHHHHHHHHHH-HT? 3PQV|A PF05190.13_MutS_IV_seed 51 119 !Q:2,2|29,30|34,37|40,40|42,44|62,65|70,74|76,79|81,81|84,85|89,91|97,99|102,102 Q:0,1|3,28|31,33|38,39|41,41|45,61|66,69|75,75|80,80|82,83|86,88|92,96|100,101|103,118 TS?HHHHHHHHHHTGGGHHHHHHHHHHHH--HHT?---TT?E---EEEETTTEEEEEEEHHH----HTTS----?T----T?EE--EEE--?SSEEE---EE?HHHHHHHHHHHHHHHH 2O8E|A PF05191.9_ADK_lid_seed 141 51 !Q:6,7|9,10|14,21|26,29|35,35|39,42|46,48 Q:0,5|8,8|11,13|22,25|30,34|36,38|43,45|49,50 EEEETT--T??EEE--------TTTB?--?SSTTB?TTT??--BEE??-GG 2BBW|A PF05192.13_MutS_III_seed 306 756 !Q:10,16|18,18|20,34|37,37|41,50|57,61|73,74|76,76|80,80|82,84|100,103|105,123|125,129|131,132|136,141|146,149|151,151|154,157|164,167|170,194|196,225|228,237|239,261|268,272|278,281|287,287|289,350|354,360|364,405|414,415|418,433|438,444|452,452|454,455|457,469|471,471|473,521|524,557|559,563|567,567|597,597|600,600|611,663|676,676|679,679|685,685|693,693|725,725|727,727|731,732|737,737 Q:0,9|17,17|19,19|35,36|38,40|51,56|62,72|75,75|77,79|81,81|85,99|104,104|124,124|130,130|133,135|142,145|150,150|152,153|158,163|168,169|195,195|226,227|238,238|262,267|273,277|282,286|288,288|351,353|361,363|406,413|416,417|434,437|445,451|453,453|456,456|470,470|472,472|522,523|558,558|564,566|568,596|598,599|601,610|664,675|677,678|680,684|686,692|694,724|726,726|728,730|733,736|738,755 HHHHHHTTSS-------S?T---------------TS?STT----------SHHHHH-??-?SSHHHHHHHHH--H-HHS?B??-HHHHHHHHHHHHHHT----T-------------------T-----H--HHH------HHHH----H-HH--?-SHHHHH----HH-------------------------H------------------------------HT----------T??---------?-----------HHHHHH-----HHHHH----TTHHH-H--------------------------------------------------------------HHH-------HHH??---------------------------------------?HHHHHHHH--HH?----?---------?HHHH-------HHHHHHB?S--S-----------??S?S-------------------------------------------------TT?-------?------------------------?B----?TTS?HHHHHHHHHHTGGGHHHHHHHHHHHHHHT?TT?EEEEETTTEE-----------------------------------------------------EEEEEHHHHTTS?TT?EEEEE?SSEEEEE?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-H-GGG--HHHH-HHHHHHHHHHHHHHHHHH 2O8E|A PF05193.16_Peptidase_M16_C_seed 181 387 !Q:1,2|14,15|18,18|28,29|32,33|41,44|51,53|55,125|127,129|133,134|137,142|149,158|161,161|172,174|176,218|220,220|234,234|241,256|258,258|263,264|272,285|289,289|291,294|301,301|305,305|307,312|314,314|317,317|328,331|333,334|338,349|365,371|375,378 Q:0,0|3,13|16,17|19,27|30,31|34,40|45,50|54,54|126,126|130,132|135,136|143,148|159,160|162,171|175,175|219,219|221,233|235,240|257,257|259,262|265,271|286,288|290,290|295,300|302,304|306,306|313,313|315,316|318,327|332,332|335,337|350,364|372,374|379,386 H??HHHHHHHHHHH??GG-GEEEEEEES??HH--HHHHHHH----HHHTTS???S-----------------------------------------------------------------------S???TTS??SS??????EEEEEE?---------TT?SEEEEEEEEE???T-------------------------------------------T?TTHHHHHHHHHHH?EEETTT----------------B?SSSS??HHHHHHH--------------STT?S---?SEEEEE-EEE?S------S?EE-EEEEEEEETT----T??HHH------------HHHHHHHHHHHHHTT-?---??HHH----HHHHHHHH 1SQB|A PF05194.7_UreE_C_seed 99 170 !Q:8,12|14,14|20,28|39,47|53,57|63,67|77,87|89,89|91,97|105,108|110,169 Q:0,7|13,13|15,19|29,38|48,52|58,62|68,76|88,88|90,90|98,104|109,109 EEEEEEEE?----S?HHHHH---------HHHHHHHTTT???------EEETT-----EEEEE---??HHHHHHHHT-----------T-T-----??EEEEEEE????S???---------------?----------------------------------------? 3NY0|A PF05195.11_AMP_N_seed 154 216 !Q:0,1|17,17|19,33|41,45|49,49|54,60|63,71|76,93|95,101|104,104|111,115|119,119|121,126|133,136|138,148|155,158|169,169|178,180|186,186|193,193|195,196|198,200|203,204|206,207|209,209|211,211 Q:2,16|18,18|34,40|46,48|50,53|61,62|72,75|94,94|102,103|105,110|116,118|120,120|127,132|137,137|149,154|159,168|170,177|181,185|187,192|194,194|197,197|201,202|205,205|208,208|210,210|212,215 ??HHHHHHHHHHHHHHS?S---------------SEEEEEE?????EEE-TTEE??-????HH---------HHHH------------------H?---???SS?EEEEEE----?SSS?E------EEEEEE????H-----------HHHHHH????TTTSHHHHHT?SEEEEGGG---HHHHH-HHHHTT?S--E---EE??T--T-S?HHHH 2V3Y|A PF05196.8_PTN_MK_N_seed 6 62 !Q:0,13|16,17|19,21|24,24|37,41|53,55|57,61 Q:14,15|18,18|22,23|25,36|42,52|56,56 ??????????????SS??B???EE?SSSSSEEEEEEE-----ETTEEEEEEEE???S????? 2LUU|A PF05198.11_IF3_N_seed 181 114 !Q:0,6|11,16|23,24|28,28|32,49|59,59|66,66|73,81|87,87|93,93|104,107 Q:7,10|17,22|25,27|29,31|50,58|60,65|67,72|82,86|88,92|94,103|108,113 ????--?BGGG??-?--SEEEEE-?TTS?EEE------------------EEEHHHHHH-HHHHTT?EEEEEE---------TTSSS?EEEEE?HHHHHHHHHH----HHHHTT 1TIF|A PF05199.8_GMC_oxred_C_seed 85 242 !Q:0,4|9,9|12,13|15,15|19,25|28,28|30,31|34,35|38,38|40,48|50,50|56,59|64,64|74,93|100,124|131,131|133,139|141,142|146,155|164,165|167,167|169,169|171,171|173,174|176,177|180,180|182,184|187,187|189,193|195,195|198,199|202,202|213,213|218,218|221,223|226,227|236,238 Q:5,8|10,11|14,14|16,18|26,27|29,29|32,33|36,37|39,39|49,49|51,55|60,63|65,73|94,99|125,130|132,132|140,140|143,145|156,163|166,166|168,168|170,170|172,172|175,175|178,179|181,181|185,186|188,188|194,194|196,197|200,201|203,212|214,217|219,220|224,225|228,235|239,241 ????-BEEE?SS--S?TTS??-----EE-E??TT??TT?H---------H-HHHHH----HHHH-HHHHHHTSG--------------------GGTTTE-------------------------EEEEES?T-------T??SHH----------HHHHHHHH--H?E-E?S??B-?TT?B-??TT?T-----T?SB?-TT?BBTTSBSEEE?SGGG?SS?-?SS??HHHHHHHH---HHH 1NAA|A PF05201.10_GlutR_N_seed 172 222 !Q:8,8|17,20|26,31|34,34|40,40|42,45|60,63|67,67|70,71|73,115|121,125|128,131|133,133|135,140|145,147|164,167|173,173|189,193|197,199 Q:0,7|9,16|21,25|32,33|35,39|41,41|46,59|64,66|68,69|72,72|116,120|126,127|132,132|134,134|141,144|148,163|168,172|174,188|194,196|200,221 EEEETTTS?HHHHHHHS???-TTHHH------HH-HHHHT?S----EEEEEEETTEEEEE----EES?TT-?H-------------------------------------------HHHHH-----TT---?T-T-----?EEEE---HHHHHHHHHHHHTTTT----SSSTT?HHHHHHHHHHHHHHH-----HHT???HHHHHHHHHHHHHHHHHHHHSS 1GPJ|A PF05202.7_Flp_C_seed 8 252 !Q:0,0|17,17|33,33|54,55|84,84|86,86|90,91|97,99|101,101|104,105|117,119|122,125|129,131|133,135|141,141|156,156|166,167|185,185|195,220|234,234|238,239|243,245|247,247|249,250 Q:1,16|18,32|34,53|56,83|85,85|87,89|92,96|100,100|102,103|106,116|120,121|126,128|132,132|136,140|142,155|157,165|168,184|186,194|221,233|235,237|240,242|246,246|248,248|251,251 ?HHHHHHHHHHHHHSSS?HHHHHHHHHHHHHTT?SSHHHHHHHHHHHHHHHHHT??HHHHHTEEEEEEEEEEETTTEEEEEEEE?S?TTS??EEEEE???S-SS??HHHHHHHHHTT???EE????BTT???S???SEESS?TTHHHHHHHHHHHH?SSGGGGSTT??STTHHHHHHHHHHHHTT?HHHHHHHHT??---???????????????-?????HHHHHHHHTSEEE?TTT??EEE?--S?S??H 1M6X|A PF05203.11_Hom_end_hint_seed 37 725 !Q:0,0|2,2|5,5|13,13|20,21|24,24|28,28|32,32|35,36|41,43|55,55|58,58|60,61|65,71|73,73|75,75|77,78|87,87|95,96|99,115|126,126|130,130|132,132|142,144|148,150|165,166|182,182|185,185|192,195|200,207|219,221|225,227|243,244|256,257|262,263|272,273|284,284|292,362|369,523|526,526|534,534|541,548|553,557|564,564|583,584|586,586|590,592|600,600|616,616|624,637|639,647|653,653|656,656|667,668|673,677|680,685|689,689|695,695|703,704|707,707|711,712|719,719|724,724 Q:1,1|3,4|6,12|14,19|22,23|25,27|29,31|33,34|37,40|44,54|56,57|59,59|62,64|72,72|74,74|76,76|79,86|88,94|97,98|116,125|127,129|131,131|133,141|145,147|151,164|167,181|183,184|186,191|196,199|208,218|222,224|228,242|245,255|258,261|264,271|274,283|285,291|363,368|524,525|527,533|535,540|549,552|558,563|565,582|585,585|587,589|593,599|601,615|617,623|638,638|648,652|654,655|657,666|669,672|678,679|686,688|690,694|696,702|705,706|708,710|713,718|720,723 ?B?TT?EEEBTTS?EEEGGG??TT?EEE?TTS?EE--EEEE?-?EEEEEEEEEEE?SS?B??SSS------?S?S?B??SEEEEETT?EEEEEEE??EE?????????????----EEEEEEEEEE?SSS?E-EEEEEEEEE???SSS--?TTHHHHHHHHHHHS-?SSSEEEEEEEGGGGG-GS?HHHHHH?---EEEE????????HHHHHHHHSSS???SSH---HHHHHHHHHHHHHHB-?TTSSEEEEESS?-HHHH--HHHHHHHH--HTTEEEEEEE?SSTTSEE-----------------------------------------------------------------------EEEEEE?????????----------------------------------------------------------------------------------------------------------------------------------------------????TT?HHHHHHH-HTTSEE--------TTEE??--?GGGGGS?HHHHHHHHHHHHHHHEEE--E?TTS?--EEEEEES?HHHHHHHHHHHHHTT?EEEEEEE???---????????S--------?EEEEE-EE?HHHHHHHHTT??STTT?????SS??????EEE?EEEEE-EEEEEEE??EE?SSS??EEEBTT?BEEE? 1VDE|A PF05204.9_Hom_end_seed 24 133 !Q:0,2|9,9|29,29|33,37|45,45|61,61|68,70|72,82|84,84|86,93|100,100|111,112|117,121|123,128|130,132 Q:3,8|10,28|30,32|38,44|46,60|62,67|71,71|83,83|85,85|94,99|101,110|113,116|122,122|129,129 ???GGGGGS?HHHHHHHHHHHHHHHEEEE?TTS?----EEEEEES?HHHHHHHHHHHHHTT?EEEEEE---E???????????S?E--------EEEEEE?HHHHHHHHTT??STTT?????S------S??? 1VDE|A PF05207.8_zf-CSL_seed 63 103 !Q:0,0|10,10|13,15|19,21|23,24|29,30|36,37|45,66|71,86|90,90|94,95|101,102 Q:1,9|11,12|16,18|22,22|25,28|31,35|38,44|67,70|87,89|91,93|96,100 ?EEETTTSEE-ET---TTT---E--EEEE?-TTSSE--EEEEHHH----------------------HHHT--------------??EEE?TTT??EEEEE?? 1YWS|A PF05209.8_MinC_N_seed 8 118 !Q:0,4|6,6|21,21|23,27|49,49|55,55|58,62|64,66|79,79|86,89|96,98|100,101|105,105|107,109|112,112|114,117 Q:5,5|7,20|22,22|28,48|50,54|56,57|63,63|67,78|80,85|90,95|99,99|102,104|106,106|110,111|113,113 ?????E-EEEEEEEEEEEEEE?S?---?HHHHHHHHHHHHTTSHHHHTT?EEEEE?TT?---?S???HHHHHHHHHTTT?EEEEEE????HHHHHH---H--GGG-T-??EE?B?--- 3GHF|A PF05211.7_NLBH_seed 3 274 !Q:0,58|60,67|73,74|79,79|83,83|107,107|113,114|120,121|128,128|145,147|150,160|164,165|181,181|185,186|195,196|198,198|205,230|255,255|269,273 Q:59,59|68,72|75,78|80,82|84,106|108,112|115,119|122,127|129,144|148,149|161,163|166,180|182,184|187,194|197,197|199,204|231,254|256,268 --???------------------?????????????????-----------????????S????????EEEEE??EEEE?TTS?HHHHHHHHHHHHHHHHHHHHTTT?EEEEE--SSGGG??HHHHHH?SEEEEEEEEEEEEEEE---EE???--------SSS??EEEEEEEEEEEEEEE?TTT??EEEEEEEE??S?EEEEEE???????????-????????????-?HHHHHHHHHHHHHHHHHHHHHHHT?HHHHHHHHHHHHH????? 2I9I|A PF05214.7_Baculo_p33_seed 18 264 !Q:0,3|27,27|55,56|71,71|74,76|93,93|97,98|100,103|127,128|132,132|149,152|155,156|186,186|189,191|196,196|204,204|206,206|211,213|242,244|246,247|249,253|263,263 Q:4,26|28,54|57,70|72,73|77,92|94,96|99,99|104,126|129,131|133,148|153,154|157,185|187,188|192,195|197,203|205,205|207,210|214,241|245,245|248,248|254,262 ????HHHHHHHHHHHHHHHHHHHTGGG?SSHHHHHHHHHHHHHHHHHHHHHHHSS??HHHHHHHHHHHHHS?TT-??HHHHHHHHHHHHHHTT?GGG??S????SHHHHHHHHHHHHHHHHHHHHTT--TSS?HHHHHHHHHHHHHHHH????SS??HHHHHHHHHHTHHHHHHHHHHHHHHHHHH-TT???EEES?HHHHHHH-H?SSSS???EEETTHHHHHHHHHHHHHHHHHHHHTTS???T--T?????HHHHHHHHT? 3P0K|A PF05221.12_AdoHcyase_seed 9 501 !Q:0,2|4,4|6,6|24,24|38,38|43,43|50,51|67,67|73,73|78,80|89,96|105,106|109,110|123,125|131,131|133,133|161,165|169,169|188,188|199,200|205,205|221,223|229,229|257,260|269,270|286,286|292,292|294,294|306,306|309,310|318,318|320,320|325,326|333,333|340,341|344,344|349,349|357,357|367,367|381,381|385,385|402,403|405,405|429,440|444,449|454,456|473,479|488,489|493,494|496,496|499,500 Q:3,3|5,5|7,23|25,37|39,42|44,49|52,66|68,72|74,77|81,88|97,104|107,108|111,122|126,130|132,132|134,160|166,168|170,187|189,198|201,204|206,220|224,228|230,256|261,268|271,285|287,291|293,293|295,305|307,308|311,317|319,319|321,324|327,332|334,339|342,343|345,348|350,356|358,366|368,380|382,384|386,401|404,404|406,428|441,443|450,453|457,472|480,487|490,492|495,495|497,498 ???B?S?GGGHHHHHHHHHHHGGG?HHHHHHHHHSTTT?TTTT?EEEEES??SHHHHHHHHHHHHTT?EEEEE?SSSS???HHHHHHHT--------TSTTEEEE??TT??HHHHHHHHHHHH?-?SSSSS?S?SEEEESSSHHHHHHHHHHHHHHHHHHH?????GGG?SSHHHHHHHHHHHHHHTT?TTHHHHHHTT??EEEE?SHHHHHHHHHHHHTT???SEEEE?TTSHHHHTTHHHHHHHHHHHHHHHHHH????TTSEEEEE??SHHHHHHHHHHHHHT?EEEEE?S?HHHHHHHHTTT?EE??HHHHTTT?S-EEEE??SSSSSB?HHHHTT??TT?EEEE?SSTTTSB?HHHHHTSTT?EEEEEETTEEEEE?TTS?EEEEEGGGSBHHHHSS??S?HHHHHHHHHHHHHHHHHHHHTTT------------SSS?----?SSEE???HHHHHHHHHHHHGGGT???????HHHHHHHT??TTS??S?TT?? 3CE6|A PF05222.10_AlaDh_PNT_N_seed 363 182 !Q:2,6|9,11|13,19|21,22|30,34|38,38|40,43|54,56|60,61|69,71|73,73|78,79|81,81|84,91|96,96|101,101|104,114|121,122|125,125|130,132|135,137|139,140|152,152|160,163|165,166|169,171 Q:0,1|7,8|12,12|20,20|23,29|35,37|39,39|44,53|57,59|62,68|72,72|74,77|80,80|82,83|92,95|97,100|102,103|115,120|123,124|126,129|133,134|138,138|141,151|153,159|164,164|167,168|172,181 EE???-?ST---T---????S??HHHHHHH-----HHT-T-?--EEEEETTTTG---GGT??HHHHHHH---T?EEES-?H-HH--------HHHH?SEEE?SS??--?------GGGGGG??TT?EEEE???GG---G-?HHHHHHHHHHT?EEEEGGG???-T--TS-??TTTHHHHHHH 2VHW|A PF05223.6_MecA_N_seed 17 134 !Q:0,3|17,17|26,26|30,31|53,55|59,67|73,81|96,99|106,106|110,110|114,114|117,117|119,121|129,130 Q:4,16|18,25|27,29|32,52|56,58|68,72|82,95|100,105|107,109|111,113|115,116|118,118|122,128|131,133 ????HHHHHHHHHHHHT?HHHHHHTB?HHH--HHHHHHHHHHTHHHHHHHHHT???EEE---------EEEEE?????????EEEEEEEEETTEEE----EEEEEE?EEE?SSS-EE-E???GGGTSTT??SSE 1MWR|A PF05224.7_NDT80_PhoG_seed 16 287 !Q:8,8|20,21|29,29|33,35|37,61|65,66|75,75|81,86|89,89|93,101|103,103|110,110|113,116|120,126|136,137|157,157|159,162|166,166|169,169|191,191|194,196|198,198|202,207|209,210|222,244|250,250|266,266|268,268|273,273|275,279 Q:0,7|9,19|22,28|30,32|36,36|62,64|67,74|76,80|87,88|90,92|102,102|104,109|111,112|117,119|127,135|138,156|158,158|163,165|167,168|170,190|192,193|197,197|199,201|208,208|211,221|245,249|251,265|267,267|269,272|274,274|280,286 EEEEETTS?EEEEEEEEETT??HHHHHHS?EEE---E????-----------------????EEE??EEEEEEEE-EETTT----??EE?EEE---------E?TTGGGS?EE????EEB???????HHHHHHHTT??SHHHHHHHHHHHEEEGGGS?G----GGS?TT?GGGGSSSSEEESSEEEEEEEE?TT???B?TTS?-----B??EEEEEEEEEEE??????????----------???EEEEE?SSSSEEEEEEEEEEE?S?EEEE?S?----GGGSGGG 2EUV|A PF05225.11_HTH_psq_seed 27 52 !Q:0,0|13,17|21,21|23,23|33,34 Q:1,12|18,20|22,22|24,32|35,51 ?HHHHHHHHHHHH-----TTS-S?HHHHHHHHT??HHHHHHHHHHHTTTTSS 2COB|A PF05227.8_CHASE3_seed 180 195 !Q:0,7|15,17|38,39|43,43|63,64|68,69|71,76|78,78|80,82|88,91|104,104|111,113|117,117|120,127|131,133|146,146|150,154|162,163|166,172|177,184|191,195 Q:8,14|18,37|40,42|44,62|65,67|70,70|77,77|79,79|83,87|92,103|105,110|114,116|118,119|128,130|134,145|147,149|155,161|164,165|173,176|185,190 ????????HHHHHHH---HHHHHHHHHHHHHHHHHHHH??HHH-HHHHHHHHHHHHHHHHHHH--HHT--T------T?H---HHHHH----HHHHHHHHHHHH-HHHHHH---HHH?GG--------GHH---HHHHHHHHHGGG?HHH-----HHHHHHH--HH-------HHHH--------HHHHHH????- 3VA9|A PF05235.9_CHAD_seed 186 515 !Q:2,2|10,15|21,22|27,27|31,40|42,43|64,64|67,67|70,73|82,82|103,110|118,125|129,129|135,202|216,217|221,224|245,248|251,251|254,254|256,257|259,261|267,308|310,344|359,362|373,428|430,430|432,432|434,434|453,456|459,461|463,472|476,477|480,483|505,505|510,510 Q:0,1|3,9|16,20|23,26|28,30|41,41|44,63|65,66|68,69|74,81|83,102|111,117|126,128|130,134|203,215|218,220|225,244|249,250|252,253|255,255|258,258|262,266|309,309|345,358|363,372|429,429|431,431|433,433|435,452|457,458|462,462|473,475|478,479|484,504|506,509|511,514 HH-HHHHHHH------HHHHT--HHHH-HTT--------??T--HHHHHHHHHHHHHHHHHHHT-TT-SS--?-HHHHHHHH-HHHHHHHHHHHHHHHHHHHH--------HTHHHHH--------HSS?TTTGG--------------------------------------------------------------------GGHHHHHHHHHHH--HHH----HHHHHHHHTSHHHHHHHHHH----HH-HH-T??S???TTTST------------------------------------------T-----------------------------------TTSBHHHHHHHHHH----HHHHHHHHHH?????------------------?---?------------------------?--?H-H-H-HHHHHHHHHHHHHHHHHG----GG---S---------?HHH--HH----HHHHHHHHHHHHHHHHHHHHH-HHHH-HHHH 3E0S|A PF05237.8_MoeZ_MoeB_seed 41 96 !Q:2,4|9,28|30,30|52,59|61,63|74,74|81,85|88,88|92,96 Q:0,1|5,8|29,29|31,51|60,60|64,73|75,80|86,87|89,91 TT?-?HHHH????---??????????--?B?HHHHHHHHHHHHHHHHHHHHT?---????S---EEEEEETTTT-EEEEEE??-??TT?TTT????- 1ZUD|1 PF05239.11_PRC_seed 114 100 !Q:2,2|6,8|11,11|15,15|18,18|20,23|29,30|39,39|55,68|76,81|83,83|86,86|89,89|92,93|96,96 Q:0,1|3,5|9,10|12,14|16,17|19,19|24,28|31,38|40,54|69,75|82,82|84,85|87,88|90,91|94,95|97,99 EE?TTS???TT?EEE?TT-S---?EEEEE--EEEEEETT-TTEEEEEEEEETTSS-------------?EEEEEGG------G?EE?SS?EE??SS?GGG 3G7F|H PF05240.9_APOBEC_C_seed 45 76 !Q:15,19|24,25|38,39|41,53|55,61|63,63|67,69 Q:0,14|20,23|26,37|40,40|54,54|62,62|64,66|70,75 STTHHHHHHHHHTTT----?EEEE??HHHHHHHHHHHB??S-------------S??-????S?HHH---HHHHHH 3VM8|A PF05247.8_FlhD_seed 29 115 !Q:0,4|28,28|31,31|39,40|50,53|62,62|66,66|73,73|77,77|82,114 Q:5,27|29,30|32,38|41,49|54,61|63,65|67,72|74,76|78,81 ??-??HHHHHHHHHHHHHHHHHHHHHHH?HH-HHHHHHT??HHHHHHHHH??--HHHHHHHH?SSS?SEEESS?SHH-HHHH?-???-----??????????????????????? 2AVU|A PF05253.7_zf-U11-48K_seed 84 28 !Q:0,1|4,4|10,10|13,13|24,24 Q:2,3|5,9|11,12|14,23|25,27 ??EE?TTTSS?EE?GGGHHHHHHH-HHH 2VY4|A PF05256.7_UPF0223_seed 35 91 !Q:0,11|31,32|34,34|51,53|70,71|82,84|86,86|89,90 Q:12,30|33,33|35,50|54,69|72,81|85,85|87,88 ????????????HHHHHHHHHHHHHHHHHHT--T?EEHHHHHHHHHHHHHH???HHHHHHHHHHHHTTSS??HHHHHHHHHH???S-EE?? 2OY9|A PF05257.11_CHAP_seed 47 180 !Q:0,0|2,4|6,11|13,14|16,16|28,30|34,44|46,46|50,50|55,64|70,70|75,83|88,90|96,107|109,110|115,116|124,127|130,131|138,149|151,151|156,156|163,163|166,168|171,172 Q:1,1|5,5|12,12|15,15|17,27|31,33|45,45|47,49|51,54|65,69|71,74|84,87|91,95|108,108|111,114|117,123|128,129|132,137|150,150|152,155|157,162|164,165|169,170|173,179 ?S???S??????S??S?TTSHHHHHHHH---TTT----------?S?GGG?SHHH----------HHHHH-HHHT?--------EEES???SSEEE------------E??TTSS??EEEEEEE---?TT??EEEEEE?----------?T-TSTT?EEEEEE?HH---HH--TTSEEEE 2IO9|A PF05259.6_Herpes_UL1_seed 14 116 !Q:0,0|4,5|8,8|18,25|28,29|33,35|38,39|43,44|55,56|71,71|81,82|88,94 Q:1,3|6,7|9,17|26,27|30,32|36,37|40,42|45,54|57,70|72,80|83,87|95,115 ?EEE??EE?SSHHHHHTS??????-?SS??EEE???SS??GGG??EEEEETTSTT??EEEEETTTTEEEEE?HHHHHHHHH--HHHHS???????HHHHHHHHHHHHHHHHHHTTT 3M1C|B PF05261.6_Tra_M_seed 8 127 !Q:0,1|7,8|27,27|30,33|54,61|98,100|121,121|125,126 Q:2,6|9,26|28,29|34,53|62,97|101,120|122,124 ??EEEEE??HHHHHHHHHHHHHHHTTT?TT--??HHHHHHHHHHHHHHHHHHHH????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHHT???HHHHHHHHHHHHHHHHHHHS?GGG?? 2G7O|A PF05264.6_CfAFP_seed 4 139 !Q:0,19|26,26|29,29|32,32|42,42|47,47|53,53|58,58|63,63|68,68|73,73|78,78|83,83|88,88|98,98|115,115|123,125|128,128|133,133|138,138 Q:20,25|27,28|30,31|33,41|43,46|48,52|54,57|59,62|64,67|69,72|74,77|79,82|84,87|89,97|99,114|116,122|126,127|129,132|134,137 ------------------??SEEESS?EE?TT?EEESEEEES?EEES?EEESS?EEES?EEES?EEES?EEES?EEES?EEES?EEES?EEEEEEEES?EEESEEEEEEEEEEES?EEETTEE???TT?EEES?EEEE? 1L0S|A PF05269.6_Phage_CII_seed 3 98 !Q:0,8|28,28|38,39|64,66|69,70|84,97 Q:9,27|29,37|40,63|67,68|71,83 ?????----HHHHHHHHHHHHHHHHHHH?HHHHHHHHT??TTTHHHHHHHHHHHHHHHHHHHHH???HH--HHHHHHHHHHHHT????????-????? 1ZS4|A PF05270.8_AbfB_seed 11 163 !Q:2,2|6,6|10,10|13,13|26,28|32,32|39,45|47,47|53,53|56,56|59,63|80,81|91,92|102,102|108,108|112,113|117,117|143,143|149,149|158,158 Q:0,1|3,5|7,9|11,12|14,25|29,31|33,38|46,46|48,52|54,55|57,58|64,79|82,90|93,101|103,107|109,111|114,116|118,142|144,148|150,157|159,162 EE-EEE?STT?TT?EEEEETTEEEEE???TTS?HHHHHH-------T?EEEEE?SS?TT-----SEEEEESSSTTEEEEE--ETTEEEEEE??SSHHHHHHH?EEEEE?TTS--SSE-EEEESSSTTEEEEEETTEEEEEESS?SSGGG?STTHHHHT?EEEE 2D43|A PF05280.6_FlhC_seed 23 195 !Q:0,10|29,30|41,41|56,59|61,65|94,95|111,115|118,124|126,132|134,134|155,155|159,160|168,169|172,175|178,195 Q:11,28|31,40|42,55|60,60|66,93|96,110|116,117|125,125|133,133|135,154|156,158|161,167|170,171|176,177 ??--???----HHHHHHHHHHHHHHHHTT??SHHHHHHSSS?HHHHHHHHHHHSSS????S?????THHHHSSHHHHHHHHHHHHHHHHHHTTT??SHHHHHHHHHHHHHH???-?SS??-----S-------S?HHHHHHHHHHHHTTSEEEEE?TTT??EEEEESS??SS????TT?????????????????- 2AVU|E PF05282.6_AAR2_seed 41 771 !Q:0,14|19,21|23,23|25,29|41,41|44,47|51,53|55,56|58,58|60,60|67,123|127,127|130,131|137,137|139,164|167,167|186,218|227,228|235,236|240,285|288,288|295,295|298,306|315,316|318,353|355,355|364,365|374,496|499,509|517,517|519,529|531,531|538,538|548,578|602,602|605,606|623,625|627,629|631,633|636,658|673,682|684,684|687,688|692,693|707,740|744,744|755,755|760,770 Q:15,18|22,22|24,24|30,40|42,43|48,50|54,54|57,57|59,59|61,66|124,126|128,129|132,136|138,138|165,166|168,185|219,226|229,234|237,239|286,287|289,294|296,297|307,314|317,317|354,354|356,363|366,373|497,498|510,516|518,518|530,530|532,537|539,547|579,601|603,604|607,622|626,626|630,630|634,635|659,672|683,683|685,686|689,691|694,706|741,743|745,754|756,759 ?------------??EEBS???S?E-----EEEETTEEEEE?TT????EEE???S--S-S?EEEEEE---------------------------------------------------------ETT?SS??EEEEE?T--------------------------TS?EEEEEEETTTTEEEEEEE----------???--------------------HHHHHHHT?-HHHHTT--SEE???-----------------------------------------??TT?HHHHHH-TT??-------HHHHHHHH??S------------------------------------S?SSEEEETT??BHHHHHHT?????------------------------??????????????------------------------------------------------------------------------------??SB?????-----?TTSGGGS?T-----------T?HHHHHH?THHHHHIII-------------------------------IIIIISSHHHHHHHHHHHHHHHH-HH??HHHHHHHHHHHHHHHT?--S???H---HH-----------------------HHHHHHHHHHHHHH----------S?SS??TTT??HHHHHHHHHTSTT----------------------------------GGG?HHHHHHHHHH?GGGT??-----???? 4ILI|A PF05292.6_MCD_seed 3 383 !Q:7,8|22,23|37,37|66,77|95,95|99,99|104,104|109,109|120,121|124,126|147,147|151,151|154,154|166,167|169,169|175,175|179,182|186,187|197,198|205,206|222,222|225,226|233,235|250,262|264,294|307,307|333,333|335,335|353,353|363,364|375,375|381,382 Q:0,6|9,21|24,36|38,65|78,94|96,98|100,103|105,108|110,119|122,123|127,146|148,150|152,153|155,165|168,168|170,174|176,178|183,185|188,196|199,204|207,221|223,224|227,232|236,249|263,263|295,306|308,332|334,334|336,352|354,362|365,374|376,380 TTTTTSS??HHHHHHHHHHHTT??SHHHHHHHHHHTS?HHHHHHHHHTTSTTHHHHHHHHHHHHHH------??????SHHHHHHHHHHHHHHHT?GGG?EEEE?SSSS?HHHHHHHHHH??TT???SHHHHHHTTSSTTEEEEEEE?TTT?SS?SEEEEEEEESS??S?HHHHH?TTS????GGG??EEEEEEEEE??STTTTS??HHHHHHHHHHHHHHH?TT??EEEEEE???SSHHHHHHHHSGGG????--------?H-------------------------------HHHTTGGGTTSS?SSSSHHHHHHHHHHHHHHHHHHHHT?B?TTSSBSSTTHHHHHTTT?EEEEEETTS??SHHHHHHHTT?EEEEE?? 2YGW|A PF05294.8_Toxin_5_seed 6 34 !Q:0,0|3,4|7,7|21,23 Q:1,2|5,6|8,20|24,33 ?EE??TT?TTHHHHHHHHTTT?--EEEETTEEEE 1SIS|A PF05299.7_Peptidase_M61_seed 10 124 !Q:21,21|28,30|33,36|61,61|79,79|86,87|96,96|103,105|112,114 Q:0,20|22,27|31,32|37,60|62,78|80,85|88,95|97,102|106,111|115,123 HHHHHHHHHHHHHHTTBTTTB?BGGGSS???SS????STHHHHTHHHHHHHHHHHHHTTSS?HHHHHHHHHHHHHHHHH-SGGGGT??HHHHHHTI-IIIITT-??TTHHHH???TTHHHHHHH 4FGM|A PF05301.6_Mec-17_seed 5 123 !Q:2,4|11,11|14,21|31,32|37,37|40,41|46,47|49,49|57,57|79,80|84,84|89,90|102,104|106,106|108,109|115,115 Q:0,1|5,10|12,13|22,30|33,36|38,39|42,45|48,48|50,56|58,78|81,83|85,88|91,101|105,105|107,107|110,114|116,122 HS?-?EEEEEE?TT????????EEEEEEEEE??EEEE?TT??EEEE??E-EEEEEEE?GGGTTSSHHHHHHHHHHHHHT??GGG?EEES??HHHHHHHHHHH???B?S??TTSEE?BTTSSTT 4H6Z|A PF05303.7_DUF727_seed 10 125 !Q:0,0|22,24|27,27|39,39|42,43|63,65|68,89|102,102|111,113 Q:1,21|25,26|28,38|40,41|44,62|66,67|90,101|103,110|114,124 ?HHHHHHHHHHHHGGGSSEEEE-??SS?EETTEEEEEEE?TT??EEEEEEETTEEEEEESSTT???TT------------------????EESSSHHHHHHH?HHHHHHHH---HHHHHHHHHHH 1SGO|A PF05307.6_Bundlin_seed 2 97 !Q:0,36|38,38|64,65|84,84|89,89|93,94|97,97 Q:37,37|39,63|66,83|85,88|90,92|95,96 -----??------------------------------S?STTTHHHHHHHHHHHHHHHHHHHHH??HHHHTTHHHHHHHHSSSS?GGGS?SSS??EE- 1ZWT|A PF05310.7_Tenui_NS3_seed 9 195 !Q:0,5|9,11|18,19|34,34|38,38|41,42|50,53|71,71|74,75|96,195 Q:6,8|12,17|20,33|35,37|39,40|43,49|54,70|72,73|76,95 ----??TTT???EETTEE??HHHHHHHHHHHHHH?TTS?HH--HHHHHHH????HHHHHHHHHHHHHHHHT?TT??GGGHHHHHHHHHHHHGGGGT????------------------------------------------------------------------------------------------------ 3AJF|A PF05321.6_HHA_seed 14 63 !Q:5,7|22,23|25,25|28,28|47,47|50,54|56,57 Q:0,4|8,21|24,24|26,27|29,46|48,49|55,55|58,62 HHHHT???HHHHHHHHHHHHHH--S?HH-HHHHHHHHHTHHHHHHHT-TS???--S??HHHHH 2K5S|A PF05326.6_SVA_seed 11 135 !Q:0,39|42,46|50,54|57,58|68,69|72,72|84,87|92,92|99,99|103,103|111,112|115,115|125,127 Q:40,41|47,49|55,56|59,67|70,71|73,83|88,91|93,98|100,102|104,110|113,114|116,124|128,134 ------------------------------???--?????EE?????SEE----?SS??EEEEEEEEE??SS?EEEEEEEEESS???-SGGG?EEEEEE?SSS?EEEEEEE??SS?EEEEEEEEE???SSSSGGG 3ES6|B PF05327.6_RRN3_seed 33 853 !Q:0,8|15,19|30,45|48,52|64,72|74,74|77,77|79,81|84,85|104,104|114,114|119,119|124,124|127,127|131,139|151,163|167,168|186,186|190,192|196,217|229,229|244,246|248,248|251,251|258,258|270,273|294,303|313,419|443,454|457,457|465,493|514,514|516,516|536,536|548,557|561,561|565,566|584,585|612,625|630,630|634,634|657,681|683,683|686,694|696,696|705,705|715,715|721,721|738,742|746,747|754,772|777,801|808,812|819,820|824,826|834,835|841,842|844,845|849,852 Q:9,14|20,29|46,47|53,63|73,73|75,76|78,78|82,83|86,103|105,113|115,118|120,123|125,126|128,130|140,150|164,166|169,185|187,189|193,195|218,228|230,243|247,247|249,250|252,257|259,269|274,293|304,312|420,442|455,456|458,464|494,513|515,515|517,535|537,547|558,560|562,564|567,583|586,611|626,629|631,633|635,656|682,682|684,685|695,695|697,704|706,714|716,720|722,737|743,745|748,753|773,776|802,807|813,818|821,823|827,833|836,840|843,843|846,848 ?????????HHHHHH-----HHHHHHHHHH----------------TT---??HHHHHHHHHHH---------S?TT?T---TS??HHHHHHHHHHHHHTGGGG?SGGGHHHHH-HHHT?TTGG-GS?HHH---------HHHHHHHHHHH-------------HHH?-GGGHHHHHHHHHHGGGS?HHH---HHH----------------------HHHHHHHHHHH?GGGHHHHHHHHHHT???T-TS?HHHHHH-HHHHHHHHHHH?---GGGHHHHHHHHHHHHHHHHH----------HHHHHHHHH--------?????????????-??????????????---------------???----????????????????????????--------?????????????????GGGHHHHHHHHHHHHHHHHHHHH------------HS?HHHHHSS-----------------------------THHHHHHHHHHHHHHTTTTS?S?SSTTHHHHHHHTTSHHHHH-HHHHHHHHHHH--------?-SSS?HHH--HHHHHHHHHHHHHHBTT??HHHHHHHHHHHHHHHHHHHHHHGGGT--------------TSSS?GGG-GHHHHHHHHHHHHHHHHHGGGG-------------------------B?TT---------S?BGGGHHHH-HHHHHHSTT?HHHHS?HHHHHHHHHHHHHTTS--???HHH--HHHHHH-------------------HHHH?????????????????????????HHHHHH-----HHHHHH??TTS???SHHHHHH--HGGGB??H--HHH???? 3TJ1|A PF05328.7_CybS_seed 48 150 !Q:0,35|62,74|101,107|138,139|149,149 Q:36,61|75,100|108,137|140,148 --------------------------------????HHHHHHHHHHHHHHHHHHHHHHHHHS-----?------?HHHHHHHHHHHHHHHHHHHHHHHHHH??----?SHHHHHHHHHHHHHHHHHHHHHHHHHHHSS-?HHHHHHHHH? 3AE5|D PF05336.8_DUF718_seed 61 131 !Q:9,11|14,14|25,31|43,43|52,52|67,71|73,74|77,79|99,101|103,103|107,107|109,120|123,123|130,130 Q:0,8|12,13|15,24|32,42|44,51|53,66|72,72|75,76|80,98|102,102|104,106|108,108|121,122|124,129 EEEEEEEEB?--TT?HHHHHHHHHT--?---?HHHHHHHHHHT?EEEEEEEE-TTTTEEEEEEEEET-----T??GG---GGGGSHHHHHHHHHHGGGB?--B?TTS?B??----------EE?EEEEEE? 1X8D|A PF05337.6_CSF-1_seed 9 335 !Q:0,37|42,53|57,57|72,74|76,77|84,84|88,90|110,113|116,116|137,140|154,178|189,213|225,225|231,233|240,334 Q:38,41|54,56|58,71|75,75|78,83|85,87|91,109|114,115|117,136|141,153|179,188|214,224|226,230|234,239 -------------???-----------------?????GGGG------------GSS?HHHHHHHHHHHHTS???S??EEEEEE?TTT???HHHHHHHHHHHHHHHHHHT????TT?HHHHHHHHHHHHHHHHGGGS????STTTTSSEEEEEE?------------------------HHHHHHHHHH-------------------------HHHHHHHHHHH?TTGGG???HHHHHT????------------------------------------------------------------------------------------------- 4FA8|E PF05339.6_DUF739_seed 11 175 !Q:0,3|22,23|43,58|60,60|71,71|78,79|91,91|108,109|131,131|148,150|152,152|160,174 Q:4,21|24,42|59,59|61,70|72,77|80,90|92,107|110,130|132,147|151,151|153,159 ????HHHHHHHHHHHHHHHHHH--HHHHHHHHHHHHHTTTSEE----------------E?SSEEEEESSS?EEEEEE??HHHHHHTHHHH-HHHTTSSSSEEEEEEE??SSSHHHHHHHHHHHHHHHHHT?EEEEEETTTTEEEEEE???S?GGGGGGS??????????????? 2PH7|A PF05343.9_Peptidase_M42_seed 69 321 !Q:0,1|6,6|8,12|16,16|24,25|27,27|35,35|39,39|48,49|66,66|75,98|102,102|106,106|108,108|119,120|123,123|128,134|142,142|164,165|167,167|169,172|182,183|198,199|210,213|217,218|222,226|230,230|240,244|247,248|264,265|270,270|272,272|275,277|286,286|289,291|302,302|306,306 Q:2,5|7,7|13,15|17,23|26,26|28,34|36,38|40,47|50,65|67,74|99,101|103,105|107,107|109,118|121,122|124,127|135,141|143,163|166,166|168,168|173,181|184,197|200,209|214,216|219,221|227,229|231,239|245,246|249,263|266,269|271,271|273,274|278,285|287,288|292,301|303,305|307,320 ??EEEE-E??---SSS-EEEEEEE??B?EEEEEEE?TTS?EEEEEESS??GGGTTTEEEEEEEETT-EEEEEEEE????--????-?????????----GGG?EEE?S?SSHHHHHHTT??TT?EEEE---????EEETTTE-EEETTHHHHHHHHHHHHHHHH??S?S----SEEEEEEES??TTTSHHHHHHHHHH??SEEEEEEEEE?-??STT??GGG????-TTS?EEEEEEETT-----EE??HHHHHHHHHHHHHTT??EEEE-E?SS???THHHHTTS-TT???EEEEEEEEBS?SSS?EEEEHHHHHHHHHH 3VH9|A PF05351.6_GMP_PDE_delta_seed 23 226 !Q:0,0|4,4|7,8|21,22|29,85|88,88|94,95|99,119|122,122|126,129|133,133|138,140|143,143|145,145|167,169|171,171|184,188|201,201|224,225 Q:1,3|5,6|9,20|23,28|86,87|89,93|96,98|120,121|123,125|130,132|134,137|141,142|144,144|146,166|170,170|172,183|189,200|202,223 ?GGG?TT??EEEEEEEEETTT??EEEEEE?????---------------------------------------?????????????TT?EEEEE??GGG---------------------GG?SEE----EEE-EEEE?-?SS?B?SEEEEEEEEETTEEEEEEEEE???B?TTSEEEEEEEEE?????HHHHHHHHHSTT?EEEEEEEEETTEEEEEEEEEEE?? 3GQQ|A PF05352.7_Phage_connector_seed 4 314 !Q:0,13|16,19|23,24|46,47|50,51|79,79|85,87|90,93|97,99|102,102|105,105|112,118|120,122|125,126|129,129|131,136|145,147|175,176|182,188|196,197|202,206|209,220|229,234|255,274|301,304|310,313 Q:14,15|20,22|25,45|48,49|52,78|80,84|88,89|94,96|100,101|103,104|106,111|119,119|123,124|127,128|130,130|137,144|148,174|177,181|189,195|198,201|207,208|221,228|235,254|275,300|305,309 ????----??????HH----HHH--HHHHHHHHHHHHHHTSEEEES??TT??HHHHHHHHHHHSEEEEEEETTTEEEEE?EEEES???TT????EEE---EE?SS?EEEEEB??----?S---SS??TT?B------EEEESSTT???SHHHHHHHHHHHHHHHHHHHHHHHHTT??EEEEE???????HHHHHHT??SSSS?????TT??----------TTSEEEEE??????HHHHHHHHHHHHHHHHHHTT????????????????????HHHHHHHHHHHHHHHHHHHHHHHHHH????EEEES???? 1H5W|A PF05353.6_Atracotoxin_seed 5 43 !Q:0,2|6,7|13,14|17,17|21,22|25,25|27,28|33,33|40,42 Q:3,5|8,12|15,16|18,20|23,24|26,26|29,32|34,39 ???TTS??SSTTS??SS?EEE??SS?S??EEES?SSTTTS-?? 1QDP|A PF05354.6_Phage_attach_seed 6 118 !Q:0,3|7,7|15,24|30,30|34,35|44,44|47,49|53,53|55,56|59,59|62,62|74,75|78,78|86,86|90,93|97,99|102,102|105,110|112,112|114,117 Q:4,6|8,14|25,29|31,33|36,43|45,46|50,52|54,54|57,58|60,61|63,73|76,77|79,85|87,89|94,96|100,101|103,104|111,111|113,113 ????SSS?SSSSSSS??????????EEEEE?TTT??EEEEEEEE?SS???SSS?S??SS?SS?EEEESSSSTTT??SS?EEEETTT?EEB????SSS???TT?BB??-???S?S???? 1K0H|A PF05355.6_Apo-CII_seed 6 78 !Q:0,13|42,42|44,45|77,77 Q:14,41|43,43|46,76 ??????????????HHHHHHHHHHHHHHHHHHHHHTTTTSSS?S??TTSSSSTTTSSSTTTTHHHHHHHHHHHHHTS? 1I5J|A PF05356.6_Phage_Coat_B_seed 2 83 !Q:0,41|82,82 Q:42,81 -------------------------------------?????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH? 1QL2|A PF05357.8_Phage_Coat_A_seed 3 75 !Q:0,7|10,10|17,18|25,25|31,32|34,35|37,37|43,44|47,47|54,55|74,74 Q:8,9|11,16|19,24|26,30|33,33|36,36|38,42|45,46|48,53|56,73 ????????SS?EEEEEE??TTSSSS?SSSSS??S??S?EEESS??SS?EEETTE--EEEEETTEEEEEEEEEEE? 1TOL|A PF05361.7_PP1_inhibitor_seed 8 155 !Q:0,22|24,25|28,30|32,32|35,41|47,47|63,63|71,75|84,84|100,101|119,154 Q:23,23|26,27|31,31|33,34|42,46|48,62|64,70|76,83|85,99|102,118 ---------------------??S??SS???S?SS???????SSSSS?SHHHHHHHHHHHHHS?SSSSTTS??-??HHHHHHHT?STTHHHHHHHHHHTT??STTHHHHHHHHHHHTTT??---------------------------------- 1K5O|A PF05362.8_Lon_C_seed 25 209 !Q:2,2|11,11|13,14|16,17|22,24|51,52|54,54|56,57|64,65|83,83|89,89|92,92|96,96|103,103|107,107|129,130|132,132|135,135|138,139|142,142|145,145|149,150|152,152|165,165|179,179|183,183|190,190|192,193|207,208 Q:0,1|3,10|12,12|15,15|18,21|25,50|53,53|55,55|58,63|66,82|84,88|90,91|93,95|97,102|104,106|108,128|131,131|133,134|136,137|140,141|143,144|146,148|151,151|153,164|166,178|180,182|184,189|191,191|194,206 EE?TTTTHHHH?S??S??STTT???BSSEEEEEEEETTEEEEEEEEEEEES--S?S-?EEEEES??HHHHHHHHHHHHHHTSS?GGGSS?SS?TTT?EEEEEE?TTB?GGGGGGGHHHHHHHHHHHHTS??B?TT?EE??EE?TT?BEE??S?HHHHHHHHHHTT?SBEEEEGGGGGGG-GGS?HHHHTS?B??EESBHHHHHHHHB?? 2X36|A PF05363.7_Herpes_US12_seed 2 86 !Q:0,0|14,14|18,20|32,85 Q:1,13|15,17|21,31 ?TTSHHHHHHHHHT?SSS???HHHHHHHHHHT??---------------------------------------------------- 1QLO|A PF05365.7_UCR_UQCRX_QCR9_seed 33 56 !Q:0,1|12,14|28,28|54,55 Q:2,11|15,27|29,53 ??HHHHHHTTTS???HHHHHHHHHHHHH-HHHHHHHHHHHHHTTTTSHHHHHHT?? 1SQB|J PF05366.6_Sarcolipin_seed 2 31 !Q:0,1|3,3|28,30 Q:2,2|4,27 ??S?SSSSHHHHHHHHHHHHHHHHHTTS??? 3W5A|C PF05367.6_Phage_endo_I_seed 6 151 !Q:0,18|33,35|39,39|47,48|54,55|59,59|63,63|71,72|86,86|89,90|97,97|106,106|108,108|119,120|126,127|134,139|143,143|146,150 Q:19,32|36,38|40,46|49,53|56,58|60,62|64,70|73,85|87,88|91,96|98,105|107,107|109,118|121,125|128,133|140,142|144,145 ??--???????????????HHHHHHHHHHHTTT???EES?EEEEEEE??EEEEE??SEE?TTS?EEEEESS??HHHHHHHHHHHHH?TT??EEEEES?TTSBSSTT?S?BHHHHHHHHT??EEESS??HHHHHS??????GGG?EE????? 1M0D|A PF05368.8_NmrA_seed 25 363 !Q:20,24|27,28|33,37|40,49|66,66|70,74|77,104|115,115|121,131|149,151|156,156|158,159|162,162|165,166|168,171|192,197|199,200|206,207|219,221|224,224|227,228|239,240|246,249|263,264|274,276|294,296|300,301|307,307|319,319|329,329|337,337|343,345|355,355|358,362 Q:0,19|25,26|29,32|38,39|50,65|67,69|75,76|105,114|116,120|132,148|152,155|157,157|160,161|163,164|167,167|172,191|198,198|201,205|208,218|222,223|225,226|229,238|241,245|250,262|265,273|277,293|297,299|302,306|308,318|320,328|330,336|338,342|346,354|356,357 EEEESTTSTTHHHHHHHHHH-----TT??EEEE?????TT----------TTHHHHHHHHHHHTTT?EEE-???-TT---------------------------?HHHHHHHHHT?SEEEE???--------GGGSGGGHHHHHHHHHH???SEEE?S??SS?TT--S????TTHHHHHHHHHHHHHHHHHH------T??BEEEE??EEHHHHTTTTT?--TT?SS??SSEEEEETTS??EEEEE---?HHHHHHHHHTTSS?-GGGTTEEEE???GGGEEEHHHHHHHHHHH---TTS??EEEEE?HHHHHHHHHTS?TTHHHHHHH-HHHHHTT?TTTSS???TTEEEHHHH?TT????? 2ZCU|A PF05369.7_MtmB_seed 3 457 !Q:0,1|4,6|20,21|43,45|48,48|51,53|72,72|83,85|96,98|104,104|108,108|113,115|118,118|121,122|128,128|131,131|134,134|148,148|151,152|156,157|161,161|166,168|194,194|197,198|202,203|205,206|216,216|221,221|230,230|237,237|252,252|258,260|267,267|288,289|295,296|302,303|305,305|324,327|332,334|337,337|359,359|365,367|371,371|375,377|394,395|413,413|417,422|435,435|454,456 Q:2,3|7,19|22,42|46,47|49,50|54,71|73,82|86,95|99,103|105,107|109,112|116,117|119,120|123,127|129,130|132,133|135,147|149,150|153,155|158,160|162,165|169,193|195,196|199,201|204,204|207,215|217,220|222,229|231,236|238,251|253,257|261,266|268,287|290,294|297,301|304,304|306,323|328,331|335,336|338,358|360,364|368,370|372,374|378,393|396,412|414,416|423,434|436,453 ??SS???HHHHHHHHHHSEE??HHHHHTTHHHHHHHHHHHHTT???TT?SS???HHHHHHHHHHHHHHHHHH?EEETTTTEEE???HHHHHHHHTS???EEEES?GGG?EEEE???TT?SS??EEEES?TT?EE?GGGHHHHHHHHHT?TT??EEE??EES?BTTB???TTSHHHHHHHHHHHHHHHHHHHHTT?TT??EEE??S??SHHHHHTTB?TTSB?TTSEEEEE?BTTTEE?HHHHHHHHHHHHTT?EEEEE???EETSSS?SHHHHHHHHHHHHHHHHHHS??SEEEE??EETTT??S?SHHHHHHHHHHHHHHHHH????EEEE???SS?SSSHHHHHHHHHHHHHHHHHT?SEEEE???GGG?STT???HHHHHHHHHHHHHHTT??HHHHHHHHHHHHHTTTT?STT??????HHHHEETTTTEE?HHHHHHHHHHHHHHHHTT??? 1L2Q|A PF05370.6_DUF749_seed 5 90 !Q:0,3|13,15|20,20|31,34|36,37|44,44|46,46|49,49|55,55|57,59|61,61|72,73|78,79|82,82|89,89 Q:4,12|16,19|21,30|35,35|38,43|45,45|47,48|50,54|56,56|60,60|62,71|74,77|80,81|83,88 ????EEEEEESTT-??SSSS?SSHHHHHTTS????S??EEEEEE?S?SS?EEEEE?S???S?HHHHHHHHHH--HHSS??SS?HHHHHH? 1IQS|A PF05371.7_Phage_Coat_Gp8_seed 7 52 !Q:0,0 Q:1,51 ?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 1IFK|A PF05372.6_Delta_lysin_seed 6 25 !Q:0,0|24,24 Q:1,23 ?HHHHHHHHHHHHHHHHHHHHHHT? 2KAM|A PF05373.6_Pro_3_hydrox_C_seed 5 103 !Q:0,0|12,12|15,22|25,26|36,36|41,42|63,63|80,80|97,101 Q:1,11|13,14|23,24|27,35|37,40|43,62|64,79|81,96|102,102 ?GGGGBSSGGGB?TT????????EE??HHHHHHHHG-GGGT??TTTHHHHHHHHHHHHHHEES?TTHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHS?????S 1E5R|A PF05374.7_Mu-conotoxin_seed 4 22 !Q:0,1|7,10|21,21 Q:2,6|11,20 ??SSSSS????SGGGTSSTTT? 1TCH|A PF05375.8_Pacifastin_I_seed 36 48 !Q:0,0|2,4|7,7|11,11|14,15|22,22|26,29|34,47 Q:1,1|5,6|8,10|12,13|16,21|23,25|30,33 ?S--?TT?EEE-ET--TEEEEE?TTS?---EEEE??????------?? 1KGM|A PF05381.7_Peptidase_C21_seed 13 112 !Q:0,0|2,2|4,4|15,17|30,30|43,45|73,73|76,76|86,86|90,94|99,105|107,111 Q:1,1|3,3|5,14|18,29|31,42|46,72|74,75|77,85|87,89|95,98|106,106 ?S-S?HHHHHHHHHH???HHHHHHHHTTTS?GGGTSSHHHHHH???HHHHHHHHHHHTEEEEEEETTEEEEES?SS?SEEEEEEEE?SSS----?EEEE-------S????? 4A5U|A PF05383.12_La_seed 33 72 !Q:16,16|27,27|30,30|46,60|71,71 Q:0,15|17,26|28,29|31,45|61,70 HHHHHHHHTSTTTGGG?HHHHHHHHTT-TT?EEHHHHTTSHHHHHH?------------??HHHHHHHHHT? 1S29|A PF05389.7_MecA_seed 42 290 !Q:0,161|164,192|209,213|215,216|237,239|242,243|258,258|261,262|264,264|266,267|269,269|276,276|280,280 Q:162,163|193,208|214,214|217,236|240,241|244,257|259,260|263,263|265,265|268,268|270,275|277,279|281,289 ????????????????????????????????????????????????????????-????????????-????????????---?????????????????---------???????????????-------??????---------------????????SE-----------------------------EEEEESSTHHHHHHHT-----T??TTEEEEEEEETTEEEEEEEE---SS??HHHHHHHHHHHHHH?EE??S?H--H-HHHHHS?EEE?SBHHHHHHH 3PXG|a PF05392.6_COX7B_seed 8 82 !Q:0,33|62,69|73,81 Q:34,61|70,72 ????????????????????????-???????-?HHHHHHHHHHHHHHHHHHHHHHHHHHHS????????TTT????????? 1V55|K PF05394.6_AvrB_AvrC_seed 6 345 !Q:0,47|49,49|52,55|64,67|70,81|108,109|127,127|130,130|140,141|145,148|152,153|166,166|169,169|175,176|180,180|207,208|224,224|236,236|242,244|264,264|267,268|287,288|292,292|310,314|316,316|319,320|329,329|342,345 Q:48,48|50,51|56,63|68,69|82,107|110,126|128,129|131,139|142,144|149,151|154,165|167,168|170,174|177,179|181,206|209,223|225,235|237,241|245,263|265,266|269,286|289,291|293,309|315,315|317,318|321,328|330,341 ????????????????????????------------????-----???S?SS-???HHHHTTTT????SS?------?????SHHHHHHHHHHHHHHHHHHHHHHTTS??SHHHHHHHHHHHHHHTS?TT?TTHHHHTSB??TTS?--?EEE??TTSTHHHHHHHT?TT?EEEEE??TTT?SEEEEEEEEEEEETTEEEEEEEEEEE??HHHHHHHHHHHHHHH?HHHHHHHHHHH?SSEEE???GGGHHHHHHHHHHHHHHHT?SS??HHHHHHHHHHHHHHHHHH??BSS?HHHHHHHHHHHHHHHTT?????B?TT??HHHHHHTS?HHHHHHHTGGGB???- 1NH1|A PF05400.8_FliT_seed 109 109 !Q:6,6|9,9|11,11|21,21|27,27|34,42|44,45|47,49|63,66|73,78|95,108 Q:0,5|7,8|10,10|12,20|22,26|28,33|43,43|46,46|50,62|67,72|79,94 HHHHHH-TT?H-HHHHHHHHH-HHHHH-HHHHHH--------?S-?S???SHHHHHHHHHHHH----HHHHHH------HHHHHHHHHHHHHHHH?????????????? 2G42|A PF05401.6_NodS_seed 7 201 !Q:0,1|23,23|50,51|73,73|87,87|95,96|100,102|104,105|114,114|147,147|156,156|158,159|181,181|186,186|195,200 Q:2,22|24,49|52,72|74,86|88,94|97,99|103,103|106,113|115,146|148,155|157,157|160,180|182,185|187,194 ??SSHHHHHHHHHTSSSGGGTTT?HHHHHHHHHHHHHHTTTSSEEEEEEE??TTSHHHHHHGGGEEEEEEEES?HHHHHHHHHHTTT?SSEEEEE??TTT???S??EEEEEEES?GGGSSSHHHHHHHHHHHHHTEEEEEEEEEEEE?HHHHHHTT?S??HHHHHHHHHHHSEEEEEEEEE?SSTT?EEEEEEEE?????? 1YUB|A PF05402.7_PqqD_seed 330 136 !Q:1,1|7,62|71,71|73,77|79,80|82,82|84,89|101,101|103,103|105,106|109,111|114,114|128,130|133,135 Q:0,0|2,6|63,70|72,72|78,78|81,81|83,83|90,100|102,102|104,104|107,108|112,113|115,127|131,132 T-EEEEE??????-----------------------------------------------???THHHHHHH-H?-?--S--S-S---?--HHHHHHHHHHH-T-T??HH---HH-HHHHHHHHHHHHH---TT??? 3G2B|A PF05405.9_Mt_ATP-synt_B_seed 31 173 !Q:0,38|63,63|73,73|79,79|145,172 Q:39,62|64,72|74,78|80,144 ???????????????????????????????????????HHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHH-HHHHH-TGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?????-??----?????---???????? 2WSS|T PF05406.10_WGR_seed 109 128 !Q:15,17|19,20|31,32|34,38|40,40|42,43|46,48|55,55|57,67|71,75|79,81|85,86|92,92|105,106|109,113|115,116|119,122|126,127 Q:0,14|18,18|21,30|33,33|39,39|41,41|44,45|49,54|56,56|68,70|76,78|82,84|87,91|93,104|107,108|114,114|117,118|123,125 EEEEEEEEEEEEETT---T--TEEEEEEEEE--E-----E?T--TS--?EEEEEE?S?----------TTS?-???EEE---EES--SHHHH-HHHHHHHHHHHH--SS?----S--TT----GGG?? 2EOC|A PF05408.6_Peptidase_C28_seed 4 257 !Q:0,45|49,49|53,53|57,62|81,109|117,117|120,121|134,138|141,143|158,158|165,165|171,171|174,177|187,187|192,193|214,217|224,234|239,249|254,256 Q:46,48|50,52|54,56|63,80|110,116|118,119|122,133|139,140|144,157|159,164|166,170|172,173|178,186|188,191|194,213|218,223|235,238|250,253 ---------------------------------------------?EEE?TTS?EEE??????SSSTHHHHHHHHHHHHTT??---------------------------TTHHHHS?SS??HHHHHHHHHHHH??-??SS???HHHHHHHSGGGSSS?EEESSS?SSEEE?SS????TTTEEEEEE?SSTT??EEEEEETTEEEEEETTEEEE????SSSEEE-----------EEES???????????TTSS??? 2JQG|R PF05409.8_Peptidase_C30_seed 5 305 !Q:15,15|17,18|20,20|22,24|32,33|44,44|48,48|66,67|70,71|76,79|82,82|102,103|107,107|109,113|116,116|119,119|139,139|143,143|148,148|152,152|157,158|163,170|172,172|187,192|194,195|198,199|201,204|218,222|235,236|250,251|254,255|262,267|277,304 Q:0,14|16,16|19,19|21,21|25,31|34,43|45,47|49,65|68,69|72,75|80,81|83,101|104,106|108,108|114,115|117,118|120,138|140,142|144,147|149,151|153,156|159,162|171,171|173,186|193,193|196,197|200,200|205,217|223,234|237,249|252,253|256,261|268,276 EEEETTEEEEEGGGG?S??S-S???HHHHHHH??GGGEEEEETT-EEE?EEEEEEETTEEEEEESS??TT??SEEE????TT?EEEEEEESSSSEEEEEEEE??TTS?B?????TT?TT?EEEEEETTEEEEEEEEEEE?TTS?EEEE?TTS?BGGG??SSSS????????B?HHHHHHHHHHHHHT------T??TT??S????HHHHHHHHHTTTB?????GGGGHHHHHHHT??HHHHHHHHHHHTT??TT??BTTBSS??????HHHHHHHHH?????----------------------- 3VB4|A PF05410.8_Peptidase_C31_seed 3 106 !Q:0,0|3,3|5,10|13,13|18,18|32,33|55,55|60,60|70,70|75,76|78,80|82,83|87,87|90,90|95,96|99,100|105,105 Q:1,2|4,4|11,12|14,17|19,31|34,54|56,59|61,69|71,74|77,77|81,81|84,86|88,89|91,94|97,98|101,104 ?SS?B??????SS?SSTT?GGGGTHHHHHHHT??GGGHHHHHHHHHHHHHHHTSB?HHHH-HHTTTTTTT?EEEE??S???S??EEE?SS?EESS??TT??EEEE? 3IFU|A PF05411.7_Peptidase_C32_seed 4 145 !Q:0,0|5,6|8,8|11,11|14,23|25,25|32,33|36,36|52,52|57,59|77,78|81,81|93,93|95,95|104,106|123,128|133,133|136,139|142,145 Q:1,4|7,7|9,10|12,13|24,24|26,31|34,35|37,51|53,56|60,76|79,80|82,92|94,94|96,103|107,122|129,132|134,135|140,141 ?SEES--B?GG-GS??--------S?TTGGGG-?SS?HHHHHHHHHHHHHSS?SSTT???SHHHHHHHHTTTEEEEE?-TT?SEEEEEESSTT?S?EEEEETTS???TTEEEEEEEEEEESSS----??SSSS?EE????SS???- 3MTV|A PF05412.7_Peptidase_C33_seed 4 110 !Q:0,0|2,4|20,21|26,36|40,41|54,54|59,59|62,65|68,68|84,84|87,90|92,93|101,109 Q:1,1|5,19|22,25|37,39|42,53|55,58|60,61|66,67|69,83|85,86|91,91|94,100 ?B???SSTTHHHHHHHHTTT??EEES???--------GGG??BHHHHHHHHHHS?EEEE?TT????TT?SEEEEEETTEEEEEE?SS---?S??SHHHHHT??-?????? 4IUM|A PF05416.7_Peptidase_C37_seed 5 575 !Q:0,407|438,439|441,441|468,468|470,470|474,476|479,479|482,483|486,486|494,494|498,498|527,540|546,546|566,566 Q:408,437|440,440|442,467|469,469|471,473|477,478|480,481|484,485|487,493|495,497|499,526|541,545|547,565|567,574 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?-------------------------------------------------------------??------????------------?------------------------------------?????-----------------------------------------------------------------------------------??HHHHTTEEEETTEEEEESSSSEEEEEGGGS??S?SEETTEEGGGEEEEEETTEEEEEESS?S?TTS???EE?SS??TT?EEEEEEE?TTS?EEEEEEEEEEEEEEEETTEEEEEEEEEE??????????????GGGTT?EEEEEETTEEEEEEEEEEE?SSSSEEEE 4IN2|A PF05419.7_GUN4_seed 79 221 !Q:8,15|27,36|42,42|44,48|52,52|57,58|66,66|84,85|95,95|99,100|103,123|133,141|144,149|152,165|171,178|182,183|185,185|188,189|191,202|205,205|215,215|220,220 Q:0,7|16,26|37,41|43,43|49,51|53,56|59,65|67,83|86,94|96,98|101,102|124,132|142,143|150,151|166,170|179,181|184,184|186,187|190,190|203,204|206,214|216,219 HHHHHHTT?-------HHHHHHHHHHH----------HHHHH?H-----HHH-HHTS??HHHHHTS?HHHHHHHHHHHHHTTTT??SHHHHHHHH-HHT--TT?--------------------HHHHHHHTT?-?------BT------TB-----??--?----TTTTS?-?-----STT--S?TT??S--------????TT?SHHHHHHHT?GGGG? 1Z3X|A PF05423.8_Mycobact_memb_seed 7 140 !Q:0,50|54,54|56,59|62,66|68,70|74,79|81,81|84,85|87,88|91,91|95,100|102,103|106,106|108,113|119,127|129,129|135,136|138,139 Q:51,53|55,55|60,61|67,67|71,73|80,80|82,83|86,86|89,90|92,94|101,101|104,105|107,107|114,118|128,128|130,134|137,137 ---------------------------------------------------EEB?B????TT?????B???TTS??????S?SS??B??EE?SSS??????B??SS?S??????BBTTB?????????S?TTSSS??S?? 2LW3|A PF05424.6_Duffy_binding_seed 409 451 !Q:0,2|4,4|10,10|12,12|14,14|18,34|36,36|38,44|46,65|67,79|90,90|103,104|106,111|115,128|131,153|156,170|189,191|193,194|198,214|225,227|235,235|238,252|259,260|263,263|265,268|270,270|272,272|287,299|308,312|314,318|320,325|329,333|335,335|337,350|352,356|358,358|360,365|367,371|376,384|387,388|390,391|393,405|407,413|415,432|434,437|440,443|446,446 Q:3,3|5,9|11,11|13,13|15,17|35,35|37,37|45,45|66,66|80,89|91,102|105,105|112,114|129,130|154,155|171,188|192,192|195,197|215,224|228,234|236,237|253,258|261,262|264,264|269,269|271,271|273,286|300,307|313,313|319,319|326,328|334,334|336,336|351,351|357,357|359,359|366,366|372,375|385,386|389,389|392,392|406,406|414,414|433,433|438,439|444,445|447,450 ???B?HHHHT?S?G-GGG-??---------?----S-S-------S---------?---------?S-------------HHHHHHHHHH-HHHHHHHHHHHH?-T------TTT?-------------SS?---------------?------HH---------------HHHHHHHHHHHHHHHHHT???B??STT----------------?HHHHHHHHHH---HHHHHHS?HH---------------HHHHTB?-TT-S?---B?H-HHHHHHHHHHHHHH-------------HHHHHTTT??---S-----S-?-?-?EEE--?--T-T-----------??-E-----E-E?-----S-----SSGG---------GT--T--S-------------S-------S-----------------?S?--?GG----GS?HHHH 4K2U|A PF05426.7_Alginate_lyase_seed 59 367 !Q:0,0|7,9|13,13|17,17|21,21|26,31|36,47|49,50|52,52|55,55|58,60|62,68|86,90|101,102|109,110|115,115|122,122|126,128|130,131|144,146|156,156|168,169|176,176|186,190|202,202|204,206|214,214|216,221|241,241|250,256|259,259|270,271|275,279|286,298|319,322|326,326|329,333|336,340|343,344|357,358|362,362|366,366 Q:1,6|10,12|14,16|18,20|22,25|32,35|48,48|51,51|53,54|56,57|61,61|69,85|91,100|103,108|111,114|116,121|123,125|129,129|132,143|147,155|157,167|170,175|177,185|191,201|203,203|207,213|215,215|222,240|242,249|257,258|260,269|272,274|280,285|299,318|323,325|327,328|334,335|341,342|345,356|359,361|363,365 ?TTSSSS?-?TTS?TTS?EEE?TTEE----??TTST------------T??S?EE?TT???G-------GGGGSSHHHHHHHHHHH-----HHHHHHHHHH??HHHHHH--HHHH-HHHHHT?TTT???S??TEEEEBTTBGGG???GGGGGGGTT-HHHHHHHHHHT--TTSSSS?HHHHHHHHH-----HHHHHHHHHHH?H---HHHHHHT?S------SHHHHHHHHHHHHHHHHTT?HHHHHHHH-------HH-HHHHTHHHHS?-TTS---??HHHHTS-------------TBHHHHHHHHHHHHHHHHHH----HHT-TT?--??TT?--??TT??SHHHHHHHHGGG--TTS?GGG? 3NNB|A PF05430.6_Methyltransf_30_seed 17 132 !Q:13,15|17,19|28,31|40,40|42,42|50,50|56,56|63,63|66,66|70,70|74,75|96,97|112,112|117,118|122,124|131,131 Q:0,12|16,16|20,27|32,39|41,41|43,49|51,55|57,62|64,65|67,69|71,73|76,95|98,111|113,116|119,121|125,130 GGGHHHHHHHHHT???S--?SEEEEEEE????EEEEEEES?H-HHHGGGS?GGGTT?EEEEEE?SS?TTT?GGG??HHHHHHHHHHEEEEEEEEES??BHHHHHHHHHHTEE-EEEE??STT???EEEEEE? 3VYW|A PF05435.6_Phi-29_GP3_seed 3 268 !Q:0,38|47,49|65,71|75,75|79,79|83,83|118,149|153,154|171,171|189,189|196,196|212,212|227,237|259,267 Q:39,46|50,64|72,74|76,78|80,82|84,117|150,152|155,170|172,188|190,195|197,211|213,226|238,258 ---------------------------------------THHHHHTT???HHHHHHHHHHHHHSS???????TTS?EEE?TTS?EEEHHHHHHHHHHHHHHHHHHHHHHHHHTTHHHH???????-????????????????????????GGG??SHHHHHHHHHHHHHTT?TTHHHHHHHHHHHHHHH-HHHHHH?BSHHHHHHHHHHHTS?HHHHHHHHHHHTTT???????????HHHHHHHHHHHHHHHHHHHTT????????? 2EX3|B PF05439.7_JTB_seed 4 120 !Q:0,17|23,23|33,34|39,40|43,43|45,46|52,52|70,72|77,77|79,119 Q:18,22|24,32|35,38|41,42|44,44|47,51|53,69|73,76|78,78 --??????--------??STTTS?EEEEEEEEE??HHHH--HH?G--GGTTT?EEEEEEETTTTEEEEEE?-?HHHH-S??--------------------------------------- 2KJX|A PF05443.6_ROS_MUCR_seed 127 186 !Q:0,58|60,78|80,99|101,113|119,120|123,123|126,126|130,132|138,138|147,147|149,149|159,159|163,164|167,167|179,180|183,183|185,185 Q:59,59|79,79|100,100|114,118|121,122|124,125|127,129|133,137|139,146|148,148|150,158|160,162|165,166|168,178|181,182|184,184 --------------------------------------------------------???S-------------------S------------------??B?-??------?--SSTTB-?SS?EE?TBT??-EESBH-HHHHHHTT?S?HHHHHHHTT?GGG??SB?TTTTTTTTTSS??SS?S? 2JSP|A PF05448.7_AXE1_seed 11 330 !Q:0,6|13,16|18,20|37,41|46,46|48,49|62,62|66,66|77,78|81,81|89,90|93,95|97,98|110,110|116,117|122,126|129,136|139,140|143,143|152,153|157,157|206,208|215,215|218,219|228,230|244,244|247,247|261,261|269,270|281,281|285,285|296,297|300,300|309,310|313,314|318,318 Q:7,12|17,17|21,36|42,45|47,47|50,61|63,65|67,76|79,80|82,88|91,92|96,96|99,109|111,115|118,121|127,128|137,138|141,142|144,151|154,156|158,205|209,214|216,217|220,227|231,243|245,246|248,260|262,268|271,280|282,284|286,295|298,299|301,308|311,312|315,317|319,329 ???????HHHHTT????S???TTHHHHHHHHHHHHHT?????EEEE?S??BTTEEEEEEEEE?GGG?EEEEEEEEES-?SS?EEEEEEE??TT??-S??SGGGHHHHTTT?EEEEE??TTSS-----SS???-????SS??SB?SSSTTTTS-?GGG?HHHHHHHHHHHHHHHHHTSTTEEEEEEEEEEETHHHHHHHHHHHHSTT-??EEEEES?SS??HHHHHHTT???GGGHHHHHHHHHH?TT?TTHHHHHHHHGGG?HHHHGGG??SEEEEEEETT?SSS?HHHHHHHHTT??SS-EEEEEETT??SS??TTH-HHHHHHHHHTT 2XLB|A PF05453.7_Toxin_6_seed 5 30 !Q:0,1|10,10|14,15|22,23|28,29 Q:2,9|11,13|16,21|24,27 ??TTSHHHHS?SSS??EEEETT--EEEE?? 2KTC|A PF05463.6_Sclerostin_seed 4 220 !Q:0,76|80,80|87,90|93,93|98,98|105,114|117,119|122,128|130,137|140,141|151,152|156,157|166,167|170,219 Q:77,79|81,86|91,92|94,97|99,104|115,116|120,121|129,129|138,139|142,150|153,155|158,165|168,169 ------------------------??????????????????????-?????????????????????-????????SSS?EEEEEE????SS?EESS?EEEEEE??????????SS???SS?----??S????????EE??EEEEEEEEE??TTS??EEEEEEEE??EE???????????????????????------????????????????????? 2K8P|A PF05464.6_Phi-29_GP4_seed 3 128 !Q:0,3|7,8|14,14|20,22|31,31|57,60|62,64|77,77|80,82|91,91|108,111|114,118|126,127 Q:4,6|9,13|15,19|23,30|32,56|61,61|65,76|78,79|83,90|92,107|112,113|119,125 -???TTS??SSGGG?SEEEE--?SSEEEEES?HHHHHHHHHHHHHHHHHHHHHHHTT???-S???HHHHHHHHHHHH?TT???EEETTEEE?HHHHHHHHHHHTTSSS????EE?????HHHHHHH?- 2FIO|A PF05472.6_Ter_seed 23 352 !Q:33,36|43,43|45,46|50,51|69,70|72,74|76,78|82,82|86,90|98,98|104,104|129,131|137,150|157,157|162,162|168,171|175,177|179,179|189,194|202,202|204,205|219,222|225,227|245,246|248,248|251,251|264,264|271,275|279,285|293,293|296,296|307,310|313,318|324,333|335,338|344,345 Q:0,32|37,42|44,44|47,49|52,68|71,71|75,75|79,81|83,85|91,97|99,103|105,128|132,136|151,156|158,161|163,167|172,174|178,178|180,188|195,201|203,203|206,218|223,224|228,244|247,247|249,250|252,263|265,270|276,278|286,292|294,295|297,306|311,312|319,323|334,334|339,343|346,351 HHHHHHHHHHHHHHHHHHHHHHTSEEEEEEEEE????BGGGTT-S??SEE??EEEEHHHHHHHHHHHTT??B???S?--SSB?SSS?????EEEEEEE?TTHHH-HHHHHHHHHHHHHHHHHHHHHTTT???HHHHH--------------HHHHTT-STTB?HHHHH????EEE---S?SEEEEEEEE------EEEEEEE?H--HHHHHHHHHHHHS????SS??-HHHHHHHHHHHHHHHHT--S?TT?EEEEEEEEEEEE-EEEEEE-----TTT-------BEEEEEE?SS?EEEEEETTTT????EE???-??EEGGG???---????S????EEEEG--GGTEEE 1ECR|A PF05475.6_Chlam_vir_seed 3 268 !Q:0,3|18,19|24,24|27,29|36,37|41,41|51,54|57,58|60,61|64,64|69,71|78,81|114,114|119,122|129,129|131,131|135,136|139,139|147,147|158,159|164,164|176,176|190,190|193,193|205,205|216,217|221,221|234,235|241,241|245,246|251,253|262,262|264,267 Q:4,17|20,23|25,26|30,35|38,40|42,50|55,56|59,59|62,63|65,68|72,77|82,113|115,118|123,128|130,130|132,134|137,138|140,146|148,157|160,163|165,175|177,189|191,192|194,204|206,215|218,220|222,233|236,240|242,244|247,250|254,261|263,263 ????EEEEETTEEEEEES??EETT?SS???TTEEEE??SSS?EEEEEEESS????EE??S??SS?EEEE???THHHHH----HHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHH?TTSS????EEEEEE?S?EEE??EE?TTTSSSS?SSEEEEEEEE??SSTT?EEEEEEEEEEE?SSEEEEEEEEETT?SS?SEEEEEEESSS?EEEEEEEEEE??SSS?EEEEEEEEEESS??EEESS?TTS??GGGS???EEEEEEEE?B???? 4JDO|A PF05479.6_PsaN_seed 3 139 !Q:0,57|59,59|61,61|64,64|66,66|70,72|75,76|83,83|85,85|88,90|92,92|95,96|98,99|101,101|105,107|110,110|115,116|118,120|122,122|125,129|132,132|134,138 Q:58,58|60,60|62,63|65,65|67,69|73,74|77,82|84,84|86,87|91,91|93,94|97,97|100,100|102,104|108,109|111,114|117,117|121,121|123,124|130,131|133,133 ???????-???????????????????????????????????-??????????????S?S?SS?S?SSS???SS??SSSSSS?S?TT???S?SS??S??S?SSS???TT?TTSS??S???S?TT?????SS?S????? 2WSE|N PF05484.6_LRV_FeS_seed 4 58 !Q:0,12|34,34|39,39|50,50 Q:13,33|35,38|40,49|51,57 ?????---?????TTTSTTTTTTGGGTSSBTTTB?SSSS?HHHHHHHHHH?GGGGGGG 1LRV|A PF05485.7_THAP_seed 139 152 !Q:0,3|5,9|12,24|26,27|30,35|38,39|41,43|47,48|52,52|60,60|63,77|81,88|91,91|96,96|101,113|115,115|120,121|123,123|126,141|143,149 Q:4,4|10,11|25,25|28,29|36,37|40,40|44,46|49,51|53,59|61,62|78,80|89,90|92,95|97,100|114,114|116,119|122,122|124,125|142,142|150,151 ????S-----SS?----------??S??SS??-???EE??S---SHH--HHH-HHHHHTT?TT?-----------??-SSS?-------EE?TTSS?STTB-------------S?TTSS??B?TT?------??-------S???-???SS 2KO0|A PF05486.7_SRP9-21_seed 33 114 !Q:0,2|18,18|22,22|27,27|31,70|81,81|84,87|93,93 Q:3,17|19,21|23,26|28,30|71,80|82,83|88,92|94,113 ???HHHHHHHHHHHHHHH?TTT?EEEE?BBT----------------------------------------TTTBEEEEEE?SS?--?EEEEE?SGGGHHHHHHHHHHHHHHHH 1RY1|C PF05488.8_PAAR_motif_seed 88 137 !Q:0,0|3,3|5,5|8,9|15,37|48,48|52,62|64,64|72,73|76,76|84,92|94,95|105,105|109,109|114,124|126,131|135,136 Q:1,2|4,4|6,7|10,14|38,47|49,51|63,63|65,71|74,75|77,83|93,93|96,104|106,108|110,113|125,125|132,134 ?BT-T?EE??BTTEB----------------?-??--?SSEEETTEEB?BTT----------?E-EEEEEET--TE-EEEEEEB??--?--?-S--SEEETTEEB?BTT?BBTT-----------S?-----BEE?? 4JIW|D PF05489.7_Phage_tail_X_seed 32 65 !Q:0,0|5,6|9,9|21,23|41,41|43,45|52,52|54,56|58,59|62,63 Q:1,4|7,8|10,20|24,40|42,42|46,51|53,53|57,57|60,61|64,64 ?EEEE?-TT?SHHHHHHHHTS??-TTTHHHHHHHSTTTTTT?S???TTEEEE?T---T??SS??S 2LTF|A PF05491.8_RuvB_C_seed 126 79 !Q:0,1|4,6|23,27|29,29|40,40|68,68|77,78 Q:2,3|7,22|28,28|30,39|41,67|69,76 ??TT???HHHHHHHHHHHHHSTT??---B?HHHHHHHHTS?HHHHHHTTHHHHHHTTSEEEETTEEEE?HHHHHHTT?? 1HQC|A PF05494.7_Tol_Tol_Ttg2_seed 160 243 !Q:14,14|19,20|23,23|25,25|29,33|46,46|59,65|67,79|81,81|84,84|89,93|110,110|116,116|118,119|121,129|131,132|136,141|143,144|146,146|148,148|158,158|163,165|177,180|184,185|187,188|198,200|202,202|223,223|231,237 Q:0,13|15,18|21,22|24,24|26,28|34,45|47,58|66,66|80,80|82,83|85,88|94,109|111,115|117,117|120,120|130,130|133,135|142,142|145,145|147,147|149,157|159,162|166,176|181,183|186,186|189,197|201,201|203,222|224,230|238,242 HHHHHHHHHHHHHT?HHHH--TT?H-HHH-----HHHHHHHTGGGB?HHHHHHHHHGGG-------T-------------T-TS?HHHH-----HHHHHHHHHHHHHHHH-HHHHT?S--S--------?E--EEE?--???S?-T-T?SEEEEEEEE-EETT---EEEEEEEEEEE----ETT--E--EEEEEEEET---T-EEHHHHHHHHHHHHHHHHTS-HHHHHHH-------HHHHH 4FCZ|A PF05495.7_zf-CHY_seed 76 134 !Q:0,0|3,5|7,9|18,19|27,42|50,58|61,63|67,77|84,85|88,89|91,91|94,105|109,111|114,114|118,118|122,131 Q:1,2|6,6|10,17|20,26|43,49|59,60|64,66|78,83|86,87|90,90|92,93|106,108|112,113|115,117|119,121|132,133 ?SS???S---EEEEETTT--TEEESSH----------------HHHHHTS---------SS???SSS??--------?EEESSS??EE-?S?SB?-----------SSS??-BS?SEE?SSS?--------?EE 2K2C|A PF05496.7_RuvB_N_seed 110 248 !Q:0,29|33,33|39,40|42,42|61,65|89,90|99,100|112,113|116,116|126,127|142,163|171,171|176,176|183,183|189,193|210,211|213,213|227,227|247,247 Q:30,32|34,38|41,41|43,60|66,88|91,98|101,111|114,115|117,125|128,141|164,170|172,175|177,182|184,188|194,209|212,212|214,226|228,246 ??-????----????----------?????TTS?SSGGG??S?HHHHHHHHHHHHHHHHHT?????EEEESSTTSSHHHHHHHHHHHHT??EEEEETTT??SHHHHHHHHHH??TT?EEEEETGGG??HHHHHHHHHHHHTS??????????????????????EEEEEES?GGGS?HHHHTT?SEEEE?????HHHHHHHHHHHHHHTT??B?HHHHHHHHHTSTT?HHHHHHHHHHHHHHHHHHT? 1HQC|A PF05497.7_Destabilase_seed 28 138 !Q:1,1|17,22|27,27|48,52|56,63|88,89|93,94|97,100|111,111|117,122 Q:0,0|2,16|23,26|28,47|53,55|64,87|90,92|95,96|101,110|112,116|123,137 S?HHHHHHHHHHHHTSS-????-EEEE-TTEEEETTTTEEHHHHHHTT?---?SSS--------HHHHHTSHHHHHHHHHHHHHHHHH--HTT??SS----HHHHHHHHHH?TTGGG-----?GGGHHHHHHHTTSTT 3AYQ|A PF05504.6_Spore_GerAC_seed 137 250 !Q:7,7|17,17|20,20|33,38|48,96|101,101|108,108|116,117|122,122|124,126|130,131|141,157|181,181|189,192|194,194|202,203|205,205|210,210|214,214|219,220|222,224|227,227|231,231|234,234|243,249 Q:0,6|8,16|18,19|21,32|39,47|97,100|102,107|109,115|118,121|123,123|127,129|132,140|158,180|182,188|193,193|195,201|204,204|206,209|211,213|215,218|221,221|225,226|228,230|232,233|235,242 EEEEEEE-ETTTTEEEE-EE?HHHHHHHHHHHT????-?EEEEEETTE-------------------------------------------------EEEE-EEEEEE-EEEEEEE-?SSSE-E---EEE--EEEEEEEEE????????--???----SHHHHHHHHHHHHHHHHHHHHHH-HHHHHTT????S?HHHHHHH--H?HHHH-HHH-GGGH--H---HH-HHH?EE-EEEEEEEE??????? 3N54|B PF05511.6_ATP-synt_F6_seed 17 105 !Q:0,40|59,60|63,63|67,68|87,87|90,93|97,104 Q:41,58|61,62|64,66|69,86|88,89|94,96 ---------------------------------??--????GGGHHHHHHHHHHHHHHT??SS-SSS??THHHHHHHHHHHHHHHHH?SS---?TTS???????? 1VZS|A PF05517.7_p25-alpha_seed 24 186 !Q:12,13|15,17|38,42|47,47|58,59|61,62|64,65|68,68|75,75|91,91|94,96|107,108|111,112|118,121|125,130|135,135|140,143|145,147|151,152|154,155|160,166|168,173|177,177|182,183 Q:0,11|14,14|18,37|43,46|48,57|60,60|63,63|66,67|69,74|76,90|92,93|97,106|109,110|113,117|122,124|131,134|136,139|144,144|148,150|153,153|156,159|167,167|174,176|178,181|184,185 HHHHHHHHHSSS-?T---TSTTSEEEHHHHHHHHHHTT??--?SSSS?HHHHHHHHHH--H??S??SE-EEHHHH-HHHHHHHHHHHSTTS?HH---HHHHHHHHTT--TT??SSSSS????TTS??????SSSS?STTS????S?--SSS??T--TTTT???????S--????TTS?BTTB??TT 1WLM|A PF05521.6_Phage_H_T_join_seed 131 169 !Q:0,0|7,14|20,21|23,27|29,30|32,33|36,39|42,42|44,51|56,57|59,59|66,68|70,73|78,78|86,86|88,90|92,94|102,104|106,110|112,117|120,120|122,125|128,133|142,142|147,147|149,154|157,157|162,163 Q:1,6|15,19|22,22|28,28|31,31|34,35|40,41|43,43|52,55|58,58|60,65|69,69|74,77|79,85|87,87|91,91|95,101|105,105|111,111|118,119|121,121|126,127|134,141|143,146|148,148|155,156|158,161|164,168 ?EEEEEE--------EEEEE--E?----S--S??EE----EE-E--------EEEE--E-EEEEEE---E?--?HHHH-HHHTTSS?T---T---EEEEEES?-?T-----T?----?TT?E----EE------EEESTTTT?EEEE?S----??EE?TTSS-?EEEEE 2KCA|A PF05522.6_Metallothio_6_seed 7 73 !Q:0,2|4,4|11,13|16,16|24,24|31,33|35,72 Q:3,3|5,10|14,15|17,23|25,30|34,34 ???S?HHHHHT???SS?SSSHHHH?TTSSSS--?S??------------------------------------ 1QJL|A PF05523.6_FdtA_seed 64 161 !Q:0,3|5,6|10,11|14,17|21,21|24,27|36,36|39,40|44,46|54,55|58,60|69,70|79,79|84,92|95,95|98,98|100,101|107,108|111,111|117,117|120,120|126,128|131,132|141,143|149,150|155,155 Q:4,4|7,9|12,13|18,20|22,23|28,35|37,38|41,43|47,53|56,57|61,68|71,78|80,83|93,94|96,97|99,99|102,106|109,110|112,116|118,119|121,125|129,130|133,140|144,148|151,154|156,160 ???-S--EEE??EE----EET-TE----EEEEEETT-TT--SSS???EEEEEES??SS??-EEEEEESS??EEEEEEES?EEEE---------EE?SS?E--EEEEE??TT-EEEEE?TT?EEEEE???TT-?EEEEEESS???GGGEE??HHHH-HHHHH 2PA7|A PF05524.8_PEP-utilisers_N_seed 186 173 !Q:0,4|8,33|35,40|42,42|46,46|51,52|65,65|67,68|74,77|83,108|113,113|115,115|126,126|141,141|143,143|163,164|166,166 Q:5,7|34,34|41,41|43,45|47,50|53,64|66,66|69,73|78,82|109,112|114,114|116,125|127,140|142,142|144,162|165,165|167,172 ?????SSB???????????----???--??????B?-----S?HHH-HHHH--HHHHHHHHHHHH-H--HHHHH----HHHHH--------------------?-----SSST-T-HHHHHHHHHT?HHHHHHHHHHHHHH?B?HHHHHHHHHHHHHHHHHTT??T-THHHHH 1EZA|A PF05527.6_DUF758_seed 14 186 !Q:0,31|51,51|77,79|109,111|135,135|151,151|162,163|184,185 Q:32,50|52,76|80,108|112,134|136,150|152,161|164,183 -----------------------?????????HHHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHHHHHTT???HHHHHHHHHHHHHHHHHHHHHHHHTSTTS???HHHHHHHHHHHHHHHHHHHTTTS?HHHHHHHHHHHHHHT?HHHHHHHTSG--GGHHHHHHHHHHHHHHHHTT?? 3F4M|A PF05532.7_CsbD_seed 119 56 !Q:0,1|18,18|21,21|31,31|44,46|48,50 Q:2,17|19,20|22,30|32,43|47,47|51,55 ??SSSHHHHHHHHHHHHT?SS?HHHHHHHTT?HHHHHHHHHHHT???H---HHHHH 1YWW|A PF05543.8_Peptidase_C47_seed 4 176 !Q:0,2|9,9|12,19|23,23|39,43|52,52|55,56|63,66|79,81|87,89|101,102|112,112|114,114|118,119|135,135|142,142|145,145|148,148|155,156|160,160|164,164|174,175 Q:3,8|10,11|20,22|24,38|44,51|53,54|57,62|67,78|82,86|90,100|103,111|113,113|115,117|120,134|136,141|143,144|146,147|149,154|157,159|161,163|165,173 -??EEEEEE?TT????????SSS?HHHHHHHHHHHHHHT?????HHHHHHHH?SS??HHHHHH????HHHHHHHHHHTT???EEESS???HHHHHHHHHTT??EEEEEEESS?B-TTB??EEEEEEEEEEEETTS?EEEEEE?TT?SS?EEEETT??EEE?TTS?EEEEEEEEE?? 1Y4H|A PF05544.6_Pro_racemase_seed 14 351 !Q:16,22|36,38|52,52|55,55|62,64|68,68|79,81|83,84|102,107|110,110|131,131|134,134|137,137|145,145|147,147|159,160|164,164|187,188|212,216|219,219|222,223|233,234|239,241|255,255|258,259|275,277|280,281|286,286|291,291|306,308|311,312|328,328|340,340|343,343|348,348|350,350 Q:0,15|23,35|39,51|53,54|56,61|65,67|69,78|82,82|85,101|108,109|111,130|132,133|135,136|138,144|146,146|148,158|161,163|165,186|189,211|217,218|220,221|224,232|235,238|242,254|256,257|260,274|278,279|282,285|287,290|292,305|309,310|313,327|329,339|341,342|344,347|349,349 EEEEEETTEEEEEEEE???????SSHHHHHHHHHHH?--HHHHHHHHSBTTS?TT?EEEEEE???STT?SEEEEEEESS???S??HHHHHHHHHHHHHTTSS???---TT?SEEEEEEEETTEEEEEEEEE?TT?SS?EEEEEEE?S?BEEEEEEEEEE??TTT?EEEEEEEESSSEEEEEEGGGGT??SSSTTHHHHHHHHHHHHHHHHHH?????SS?TT??SEEEEEEEE??SSTT?--SEEEEEEETTTEE?SS??HHHHHHHHHHHHHTT???TT??EEEE-ETTS?EEEEEEEEEEEEET???TT??TTSSEEEEEEEEEEE?EEEEEEEEEEE?TT?TTTT?B? 4J9W|A PF05550.6_Peptidase_C53_seed 11 168 !Q:0,23|25,25|29,29|34,39|44,45|48,51|53,54|58,58|62,71|76,78|92,93|95,95|101,101|109,111|126,126|137,137|147,149|154,156|159,161|167,167 Q:24,24|26,28|30,33|40,43|46,47|52,52|55,57|59,61|72,75|79,91|94,94|96,100|102,108|112,125|127,136|138,146|150,153|157,158|162,166 -----------------???????B?TTS?BSSS??????TTSS??SS????S??EEE?GGG??????????BTTB???EEEEETTTEEEEE??S?BBSSB?GGGEEEE???SSEEEEEEEEBTTS?EEEEEEETTS?EEEEESSTT???EEEE???SS???EEEEE? 3ZFT|A PF05551.6_zf-His_Me_endon_seed 11 161 !Q:3,4|6,7|10,13|15,18|35,35|37,42|44,44|53,53|60,60|62,62|68,82|91,92|96,97|115,120|124,133|135,142|145,148|151,152|155,155|158,160 Q:0,2|5,5|8,9|14,14|19,34|36,36|43,43|45,52|54,59|61,61|63,67|83,90|93,95|98,114|121,123|134,134|143,144|149,150|153,154|156,157 EEE--B??SS----S??-?TTEEEEETTEEEEEEE?S------S?EEEEETTT-GGGSSS?S-EETTE---------------EEEEEESS??TTB??GGGEEEEEHHHHHHGGG??---?TTT----------T???-----SS??--SS??TT?SS??? 1CZ0|A PF05552.7_TM_helix_seed 143 73 !Q:0,15|20,27|51,57|65,65|67,68 Q:16,19|28,50|58,64|66,66|69,72 ????????????----TTSS--------HHHHHHHHHHHHHHHHHHHHHHH-------HHHHHHH?S-?HHHH 4AGE|A PF05566.7_Pox_vIL-18BP_seed 2 126 !Q:0,19|21,23|25,27|43,43|49,49|61,64|71,71|77,79|97,98|123,125 Q:20,20|24,24|28,42|44,48|50,60|65,70|72,76|80,96|99,122 ------------------??S???S???EEEEETTEEEEEEEE?SSTTS?EEEEEEEETTS????EEGGGS?TTEEE???EEEEETTEEEEEEEEEE??TTTTTTEEEEEEEEETTEEEEEEE??? 3F62|A PF05567.6_Neisseria_PilC_seed 9 430 !Q:0,9|12,12|14,14|17,17|25,25|29,29|40,42|48,48|52,52|56,61|64,70|74,92|99,109|118,120|126,127|141,141|145,145|153,153|155,159|162,163|166,166|177,177|180,195|197,198|200,201|206,206|217,218|221,221|224,231|242,247|255,256|261,263|271,271|278,279|295,295|297,297|300,301|307,308|311,311|319,319|326,330|334,334|336,336|340,340|342,345|347,348|353,353|365,369|376,378|381,382|390,393|396,405|415,416 Q:10,11|13,13|15,16|18,24|26,28|30,39|43,47|49,51|53,55|62,63|71,73|93,98|110,117|121,125|128,140|142,144|146,152|154,154|160,161|164,165|167,176|178,179|196,196|199,199|202,205|207,216|219,220|222,223|232,241|248,254|257,260|264,270|272,277|280,294|296,296|298,299|302,306|309,310|312,318|320,325|331,333|335,335|337,339|341,341|346,346|349,352|354,364|370,375|379,380|383,389|394,395|406,414|417,429 ??????????EE?S?SS?HHHHGGG?TTS?HHHHHHHHHT???EEEEE?SSS?EEE?----?SS?---???EEE??-----------------HHHHHH???????????HHHHHHHH???EEEEE--EETTEEEEEEEEE?TTS?SEEEEEE?S-----SG--GG?EEEEEEETTT?TT--------------??B??S??EEEE?TTSSEEEEEE??BS?TT------??EEEEEEETTT--??--EEEEEEE??STTS???EEEEEEE?TTSSSB??EEEEEETTSEEEEEE?S?SS??TTSTT??TT?SGGGGGG?EESGGG---??SEE?B?TTS?B????S??EEEE?TTSSSEEEEEE?????SGGGGS???SS??EEEEEEE???-SS??????????GGGEEEEEE--EEEEEEEETTEEE 3HX6|A PF05572.8_Peptidase_M43_seed 5 182 !Q:0,0|4,4|8,15|19,19|27,27|30,30|33,34|41,42|46,48|52,52|59,59|64,64|69,70|73,73|88,90|93,95|102,113|115,115|119,121|124,126|128,131|134,134|137,137|139,149|151,152|158,160|162,162|165,166|168,168|182,182 Q:1,3|5,7|16,18|20,26|28,29|31,32|35,40|43,45|49,51|53,58|60,63|65,68|71,72|74,87|91,92|96,101|114,114|116,118|122,123|127,127|132,133|135,136|138,138|150,150|153,157|161,161|163,164|167,167|169,181 -ETT?GGG????---?TTT?EEEEEES?EE?TT??EESEEE??TTS--?GGG?SEEEEG-GGSS-SSTT??TS?SSHHHHHHHHHHTT???TT???BTTTTS??---------?S?TTS???SS???S????TT?TT-T--------???T--TBTTS???G-GG??B?BHHHHHHHHHHHH- 2J83|A PF05573.7_NosL_seed 50 176 !Q:0,43|51,51|53,53|56,59|64,64|74,78|81,82|84,84|86,86|95,96|99,101|104,104|106,112|119,124|136,136|140,142|148,148|160,161|170,171 Q:44,50|52,52|54,55|60,63|65,73|79,80|83,83|85,85|87,94|97,98|102,103|105,105|113,118|125,135|137,139|143,147|149,159|162,169|172,175 --------?????--?????????????????????????????EEEEESS?S-SE----EEES?HHHHHHHHT-----TT??S-S?EEEEEEEE??TT???SS?S??----?EEEEGG------GSEEEEESSSS?TTS???EEEES?HHHHHHHHHHT-?EEEEEGGG??HHHH 2HQ3|A PF05577.7_Peptidase_S28_seed 12 494 !Q:3,3|6,6|9,11|21,21|24,25|29,30|37,41|44,44|52,52|54,55|72,73|79,80|89,90|97,97|115,115|124,125|145,145|149,149|157,158|161,161|167,167|185,188|190,190|216,217|226,228|231,234|236,236|255,256|258,259|261,261|269,269|281,295|297,300|303,306|318,322|330,331|333,333|336,353|356,356|368,373|375,375|377,380|386,386|388,390|396,396|404,410|412,415|423,424|426,426|429,430|433,435|444,444|451,454|456,456|469,470|477,479|481,483|494,494 Q:0,2|4,5|7,8|12,20|22,23|26,28|31,36|42,43|45,51|53,53|56,71|74,78|81,88|91,96|98,114|116,123|126,144|146,148|150,156|159,160|162,166|168,184|189,189|191,215|218,225|229,230|235,235|237,254|257,257|260,260|262,268|270,280|296,296|301,302|307,317|323,329|332,332|334,335|354,355|357,367|374,374|376,376|381,385|387,387|391,395|397,403|411,411|416,422|425,425|427,428|431,432|436,443|445,450|455,455|457,468|471,476|480,480|484,493 EES?SS?SS???EEEEEEEEE?TT??TTT-?EEEEEE---??SS?HHHHHHH?H--HHHHHHHHHTEEEEEE??TTSTT??TTGGGGGS-?TTTSTT?SHHHHHHHHHHHHHHHH-HHSTTGGG??EEEEEETHHHHHHHHHHHH?TTT?SEEEEET??TT?STTSS?TTHHHHHHHHHHHTTST----T-HHHHHHHHHHHHHHHTTSHHHHHHH--HHHTTBSS???TT----S-HHHHHHHHHHHHHHHHHT??S--S?EESSSEE?SSHHHHHHHHS?------??------S??--HH----HHHHHHHHHHH-----HHHHTTS??S-SB???---??????------HH-HHHHHHHHHHT??????B?S----SSSSS?B???HHHHH-HHHHHHH-------S????TTHHHHH--H?TT??TT???EEEEEESS?GGGGGS--??S?SSSSEEEEEETT??SSGGGS???S???HHHHHHHHHH- 3N0T|A PF05579.8_Peptidase_S32_seed 6 311 !Q:0,107|110,111|145,145|162,162|173,175|178,179|181,183|185,186|188,189|192,193|219,221|225,225|233,233|240,247|251,251|255,255|260,261|271,272|274,274|278,278|281,284|289,291|304,310 Q:108,109|112,144|146,161|163,172|176,177|180,180|184,184|187,187|190,191|194,218|222,224|226,232|234,239|248,250|252,254|256,259|262,270|273,273|275,277|279,280|285,288|292,303 --------------------------------------------------------?????-----------??---------------------------???????SS??TTEEEEESSSEEEEEEEEETTEEEEEEEGGGSB-TTEEEEEETTEEEEEE?EEETTEEEEE?--TT??S???B??B??TT??EEEEEEETTEEEEEEEETTEEEESS???STT?EEEETTS?EEEEEE????????EEE?TTS?EEEB??EEHHHHHTT??S?EEE?TT????TTEE???SEEEHHHHHHHH??????- 3FAO|A PF05581.7_MCP_N_seed 2 103 !Q:0,32|73,76|95,95 Q:33,72|77,94|96,102 ---------------------------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH???-HHHHHHHHSSHHHHHHSS?EEEEETT 3C8C|A PF05588.6_Botulinum_HA-17_seed 3 150 !Q:0,5|8,8|36,38|43,43|65,65|70,70|78,81|85,85|107,107|112,112|117,119|123,124|127,127|129,129|134,135|138,139|148,149 Q:6,7|9,35|39,42|44,64|66,69|71,77|82,84|86,106|108,111|113,116|120,122|125,126|128,128|130,133|136,137|140,147 ??????SS?SEEEEEEETTBSSEEEEEETTEEEEEE???SGGG?EEEEEETTTTEEEEEETTSTT?EEEE?SSSBEEE----ESS?GGGEEEEEEEETTEEEEEESS?SSSS?EEEE???SSS??TT?B?EEEE??SS??TTTEEEEE?? 1YBI|A PF05592.6_Bac_rhamnosid_seed 25 692 !Q:24,24|26,28|31,31|42,53|57,57|60,62|66,74|77,79|85,100|104,111|114,115|118,119|130,131|134,141|144,145|147,156|166,170|172,172|179,179|196,196|203,203|205,205|210,213|230,231|246,247|249,249|251,267|269,274|280,281|283,289|291,292|294,295|314,315|340,345|348,351|353,353|355,356|360,372|375,378|383,383|404,414|434,435|439,453|457,463|475,475|477,487|492,492|509,513|516,517|529,530|533,533|543,544|556,556|558,558|561,562|569,569|573,573|575,578|582,583|585,586|589,589|603,604|606,618|630,633|635,635|639,639|642,649|659,659|669,670|674,674|682,682|685,685 Q:0,23|25,25|29,30|32,41|54,56|58,59|63,65|75,76|80,84|101,103|112,113|116,117|120,129|132,133|142,143|146,146|157,165|171,171|173,178|180,195|197,202|204,204|206,209|214,229|232,245|248,248|250,250|268,268|275,279|282,282|290,290|293,293|296,313|316,339|346,347|352,352|354,354|357,359|373,374|379,382|384,403|415,433|436,438|454,456|464,474|476,476|488,491|493,508|514,515|518,528|531,532|534,542|545,555|557,557|559,560|563,568|570,572|574,574|579,581|584,584|587,588|590,602|605,605|619,629|634,634|636,638|640,641|650,658|660,668|671,673|675,681|683,684|686,691 EEEEETTEEEEEEEEEEEEEEEEE-E???TT?EEEEEEESEE?-----------TTS?EE--?GGG---------TT???EEEEE?-----------???-SSE--------EE??SS??EEEEEEEEES?-SS?-----??GG--G----------EEEEEEEES---??B?EEEEES?HHHHHHHHHHHHHHHH-TBSSSB?S?SSSS????BHHHHHHHHHHHHHHB??HHHHHHHHHHHHHH??T-T-----------------S----??BSBSS??T-------T??B??TTTTTHHHHHHHHHHHHH??HHHHHHHHHHHHHHHHHHHHTSBT------TB--??S?S??STT------------?SS????HHHH-HHHHHHHHHHHHHHHHHHTT?-------?-?HHHHHHHHHHHHHHHHHHB-?TTS--------------?BTT??-----HHHHHHHHHTT?S----------?GGGH-HHHHHHHHHHHHHTTS?????TT--THHHHHHHHHH--TT?HHHHHHHHH??SSSSSHHHHHT-T?SS??SSTTSB?TTS?B--??TTS??S??SG-GGGGHHHHHHHTS??E-------------EEEGGGTEEEE????B-TTB?EE--------EEEEEETTE-EEEEEEEEE--TTE-EEEEEEE?TT?EEEEEE 3W5M|A PF05618.6_Zn_protease_seed 11 160 !Q:16,16|22,22|25,25|32,32|51,56|75,93|116,124|126,130|132,132|137,137|152,154|157,159 Q:0,15|17,21|23,24|26,31|33,50|57,74|94,115|125,125|131,131|133,136|138,151|155,156 EEESEEEEEEGGGTEE-EEEEE?TT?SSEEEE?EEEEEEEETTEEEEEEEE------EETTEEEEEEEEEEEEEE???????????---?????EEEEEEEEEEETTEEEEEEEEE---------E?????S?SEEE?HHHHHHTTEEEETT???TT??? 2PMA|A PF05622.7_HOOK_seed 9 758 !Q:0,4|6,8|21,23|26,28|47,47|52,52|59,60|63,63|67,67|91,95|99,101|109,110|142,142|160,757 Q:5,5|9,20|24,25|29,46|48,51|53,58|61,62|64,66|68,90|96,98|102,108|111,141|143,159 ??--?S--?HHHHHHHHHHTT???SS???SHHHHTTSHHHHHHHHHH?TTTS?HHHHTT??SG-GGG?SHHHHHHHHHHHHHHHHHHHTTT?????TTT???HHHHHTT??HHHHHHHHHHHHHHTTSSSTHHHHHHHHHHS?HHHHHHHHHHHHHHHHH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?-------------------------------------------------------?------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------???? 1WIX|A PF05625.6_PAXNEB_seed 30 593 !Q:0,32|35,40|43,47|52,53|62,63|65,65|73,73|82,82|89,89|92,93|111,121|123,124|131,132|134,137|144,144|148,233|237,238|245,245|248,250|258,258|262,357|372,381|396,396|401,401|410,415|433,433|447,453|472,477|480,482|486,592 Q:33,34|41,42|48,51|54,61|64,64|66,72|74,81|83,88|90,91|94,110|122,122|125,130|133,133|138,143|145,147|234,236|239,244|246,247|251,257|259,261|358,371|382,395|397,400|402,409|416,432|434,446|454,471|478,479|483,485 ??-------??----------------------TT------BT-----TEEE?-SSSSSEEE??S?HHHHHHH-TSSSEETT?EEEEEE?SS??HHHHHHHHHHHHHHHHH???????????B??EEEEEE?-S---?GGGTTS?EEE????????????????????????---??????????????????????????????????????--------------?????-?TTS??EEEEEE?SS???TTTEEEE?SSS?-----------------------------------------------------------------------------------------------HHHHHHHHHHHHHH----------TTTSEEEEEEEEET?TTTS?GGGGSHHH------HHHHHHHHHHHHHHTTT-TEEEEEEEEGGGS------?HHHHHHHHHHSSEEEEEE??????EE---EEE???????---????????????????????-???????----??????????-???????????????????????????--------------------------- 4EJS|A PF05627.6_AvrRpt-cleavage_seed 22 40 !Q:0,10|17,18|21,23|26,26|31,39 Q:11,16|19,20|24,25|27,30 -??????????SGGGTT?-TT???SS?EEEE??????--- 2NUD|C PF05630.6_NPP1_seed 27 282 !Q:9,10|15,16|19,21|23,24|26,26|30,30|33,83|87,88|92,96|105,105|107,108|110,111|125,126|129,130|132,134|148,150|154,156|174,175|190,191|194,197|202,202|205,206|208,220|225,229|233,233|235,235|242,248|251,253|256,265|268,269|271,271 Q:0,8|11,14|17,18|22,22|25,25|27,29|31,32|84,86|89,91|97,104|106,106|109,109|112,124|127,128|131,131|135,147|151,153|157,173|176,189|192,193|198,201|203,204|207,207|221,224|230,232|234,234|236,241|249,250|254,255|266,267|270,270|272,281 HHHHHHHHT??EEEE-?SS???B??B?TTS?EE?????--------?-???--------------------------------?GGG??GGG---??EEEEEEEE-T--T--EEEEEEEEEEEEE??SS--S??-EEEEEEEEEEEES?--TTT?-?EEEEEEEETTEEEEESS??GGGEETTEEEEEEE??TT?-??EEEE?SS??B----------???EEEG-----GGS?H-HHHHHH-------HH???TT?-------??SS--S-TTHHHHHHHH 3ST1|A PF05635.6_23S_rRNA_IVP_seed 122 124 !Q:0,1|4,6|8,8|24,24|30,30|33,33|59,66|93,93|95,95|97,97|101,106 Q:2,3|7,7|9,23|25,29|31,32|34,58|67,92|94,94|96,96|98,100|107,123 ??GG---G?HHHHHHHHHHHHHHH-HGGGS?GG-GTTTHHHHHHHHHHHHHHHHHHHTT??--????HHHHHHHHHHHHHHHHHHHHHHHHTT?S?H-HHH------HHHHHHHHHHHHHHHHH 2RLD|A PF05636.6_HIGH_NTase1_seed 10 447 !Q:0,1|7,9|12,13|25,27|37,37|39,42|47,47|50,50|63,63|69,71|76,76|85,85|94,96|102,103|105,108|121,125|132,140|148,154|159,161|164,176|183,184|190,191|199,203|205,205|207,215|224,245|249,249|258,258|273,273|278,281|284,287|292,292|297,300|302,302|306,315|318,318|328,330|332,346|352,360|366,366|368,371|373,374|376,382|388,396|404,406|409,424|428,436|442,443|445,446 Q:2,6|10,11|14,24|28,36|38,38|43,46|48,49|51,62|64,68|72,75|77,84|86,93|97,101|104,104|109,120|126,131|141,147|155,158|162,163|177,182|185,189|192,198|204,204|206,206|216,223|246,248|250,257|259,272|274,277|282,283|288,291|293,296|301,301|303,305|316,317|319,327|331,331|347,351|361,365|367,367|372,372|375,375|383,387|397,403|407,408|425,427|437,441|444,444 ??EEEEE???TT??HHHHHHHHHHH---TSSEEEEEE?T----TSSB?SS?HHHHHHHHHHHT?SEEEE???GGGS?HHHHHHHH-HHHHHHHT-??EEEEE??H----HHHHHHHHHHTT---??EEEETT---------EEEETTT?-----?EEES???GG-------------GHHHHH--HHHHH--HHHHHTT?????E?S----???-?HHHHHHHH----------------------HTT?GGGTGGGS?HHHHHHHHHHHHTT?SGGS????HH----HHHH-HHHH----S?GGG----------TS?HHHHHHHHH---H?------------??SSHHH---------HHHHS?T----T??H-------HHHHH---------HHHHHHH???HH----------------HHH---------HHHHH??S?? 3GMI|A PF05637.7_Glyco_transf_34_seed 14 327 !Q:0,6|13,13|17,23|25,25|43,52|54,54|60,60|62,63|65,68|75,78|92,92|95,95|102,102|105,105|109,109|114,130|133,133|137,141|143,147|150,151|156,157|165,172|189,189|193,208|220,230|239,241|245,260|271,272|274,296|305,305|316,316|319,320 Q:7,12|14,16|24,24|26,42|53,53|55,59|61,61|64,64|69,74|79,91|93,94|96,101|103,104|106,108|110,113|131,132|134,136|142,142|148,149|152,155|158,164|173,188|190,192|209,219|231,238|242,244|261,270|273,273|297,304|306,315|317,318|321,326 ???????EEEEEE?SST-------T?HHHHHHHHHHHHHHHHH----------T?EEEEE?S??S??--SHHHHH----HTHHHHHHHHHHH?TT?SEEEEE?TT-EEE?TTTT-----------------TS?GGG-----T?????TT??EEEE??TTTSSSS------??TTEEEEEGGGHHHHHH-HHH----------------TTTSTTTTSTT-----------THHHHHHH---THH----------------HHSTTSEEEE??T-----------------------TTSEETTT?TTTGGGSEEE?TT??HHHHHH 2P73|A PF05638.7_DUF796_seed 152 188 !Q:4,4|6,8|19,19|27,27|30,31|33,34|36,37|44,44|48,49|52,70|73,74|82,82|95,95|97,97|110,113|117,128|130,130|142,142|153,170|179,179 Q:0,3|5,5|9,18|20,26|28,29|32,32|35,35|38,43|45,47|50,51|71,72|75,81|83,94|96,96|98,109|114,116|129,129|131,141|143,152|171,178|180,187 EEEE-E---ETTTEETTTT?SSHHHHG-GG??T--T-?TTSEEE?EEE??EE?????-----?????????EE??EEEEEES?SSHHHHHHHHHH-T?EEEEEEEEEEEE---?TTS------------S-EEEEEEEEEEE-EEEEEEEEEE????-----???????-?EEEEEEEE?SEEEEEET 3HE1|A PF05639.6_Pup_seed 15 72 !Q:0,29|57,71 Q:30,56 ???????????????-----------????TTTHHHHTTTTTTTTTHHHHHTTTSSS??????????????? 3M91|B PF05641.7_Agenet_seed 34 96 !Q:0,1|4,4|11,19|33,38|44,69|78,82|84,87|90,94|96,96 Q:2,3|5,10|20,32|39,43|70,77|83,83|88,89|95,95 ??TT?EEEEEE??????-??EEEEEEEEEEETT------EEEEE???????------------------?EEEEEGGG-----E----EE?????B- 3KUF|A PF05643.6_DUF799_seed 3 215 !Q:0,35|40,42|45,45|48,48|68,68|71,72|85,87|95,95|104,105|118,126|141,142|154,154|158,159|178,214 Q:36,39|43,44|46,47|49,67|69,70|73,84|88,94|96,103|106,117|127,140|143,153|155,157|160,177 -------------------------???????????EEEE???EE?SS?GGGGTTHHHHHHHHHHHTT?EE??HHHHHHHHHHTT???HHHHHHS?HHHHHHHH??SEEEEEEEEEEE?????????EEEEEEEEEEETTT??EEEEEEEEEEE?TTS??HHHHHHHHHHHHHHHHHS???----------------------------?????? 4HRV|A PF05645.8_RNA_pol_Rpc82_seed 29 401 !Q:14,119|122,122|124,125|129,129|147,170|175,175|193,231|242,243|246,248|252,360|371,371|374,376|378,387|390,390|392,392 Q:0,13|120,121|123,123|126,128|130,146|171,174|176,192|232,241|244,245|249,251|361,370|372,373|377,377|388,389|391,391|393,400 HHHHHHHHTTSEEE???--------------???????????????????????--------?????????????????????????????????????-------------????????TT?S--EEE?HHHHHHHHHHHHHHHHH------------------------HHHT?SHHHHHHHHHHHHTTSS???????-----------------------------???EEHHHHHHTS-?SS???HHH-------------------------------------------------------------------------------------------------------------HHHHHHHHHS?TT-??B??????????EE?B?HHHHHHHH 2XV4|S PF05649.8_Peptidase_M13_N_seed 156 1009 !Q:2,2|15,18|20,20|22,22|26,39|42,42|49,51|59,87|94,96|100,190|192,209|225,226|231,241|256,256|260,290|295,366|375,378|383,396|401,401|403,407|413,414|417,419|421,423|426,428|436,446|449,450|452,452|458,458|461,493|503,503|514,518|520,525|527,556|558,558|561,573|581,583|591,591|595,606|610,611|613,618|623,623|628,645|650,656|663,667|669,670|673,678|680,693|695,695|704,733|737,746|753,774|777,779|791,793|795,795|798,802|820,821|823,823|836,856|861,863|865,874|879,879|884,884|887,889|892,893|901,912|918,931|950,952|954,954|956,956|959,965|967,967|970,973|980,980|983,996|1000,1000|1005,1005|1008,1008 Q:0,1|3,14|19,19|21,21|23,25|40,41|43,48|52,58|88,93|97,99|191,191|210,224|227,230|242,255|257,259|291,294|367,374|379,382|397,400|402,402|408,412|415,416|420,420|424,425|429,435|447,448|451,451|453,457|459,460|494,502|504,513|519,519|526,526|557,557|559,560|574,580|584,590|592,594|607,609|612,612|619,622|624,627|646,649|657,662|668,668|671,672|679,679|694,694|696,703|734,736|747,752|775,776|780,790|794,794|796,797|803,819|822,822|824,835|857,860|864,864|875,878|880,883|885,886|890,891|894,900|913,917|932,949|953,953|955,955|957,958|966,966|968,969|974,979|981,982|997,999|1001,1004|1006,1007 TT?HHHHHHHHHHHH????T-T?SEE--------------EH-HHHHHH---HHHHHHH-----------------------------HHHHHH---HTT???----------------------------------------------------------------------------------------T------------------TSHHHHHHHHHHHHH?-HHHH-----------HHHTTGGGHHHHHH-HHT-?----------------?------------SHHH------------------------------------------------------------------------HHHHHHHH----HHTT-----------???SEEE-E-----EEEET--TE---E---EE---EEEEEEE-------??-?SS--S?GGGGT?GG---------------------------------GHHHHHHHH-HHHHHHHHHH-----H------S------------------------------S?GG-------------GGHHHHH---HHHHHHH-HHH------------HHS??H------HHHT?TTTT----------------??EEEH-------HHHHHH-----T--TT------S?-------------H-HHHHHHHT??----------------------------TTT-------?--SEEEES?---------------------HH---HHHHHHHHHHH---S?HH-----HHHHHHHHHHHHHHGGG--S?HHHHHHHHHHHT---------------------HHHH???S?-??------HHHH-HHHH-HH---HH--HHHHHHH------------HHHHH--?????-?----?HHHHHHHHHHHHHHHHHH---H-T?TT-------S?HH----HHHHHH-HH--------------HHT?EEEE-ES? 1DMT|A PF05652.7_DcpS_seed 20 168 !Q:0,1|5,6|28,38|48,51|53,55|59,86|93,111|119,119|129,130|135,147|156,157|166,167 Q:2,4|7,27|39,47|52,52|56,58|87,92|112,118|120,128|131,134|148,155|158,165 ??SSS??EEEEEEEEETTTTEEEEEEEE?????????--EEEEEEEEE????H---HHH----------------------------HHHHTS-----------------??EEEEEEE?SSEEEEEEE??HHHH------------?EEEEEESS??HHHHHHHS?? 1XMM|A PF05658.9_YadA_head_seed 239 30 !Q:1,1|5,5|12,12|15,17|21,21|28,29 Q:0,0|2,4|6,11|13,14|18,20|22,27 E?STT?EEESTT?EE--?STT?EEESTT?? 3LA9|A PF05662.9_YadA_stalk_seed 75 24 !Q:0,3|5,10|14,15|17,19 Q:4,4|11,13|16,16|20,23 ????S??????STT??S???HHHH 3LA9|A PF05669.7_Med31_seed 34 143 !Q:0,3|26,27|29,29|31,39|43,60|73,73|85,85|87,87|89,89|97,98|107,108|110,110|114,129|136,142 Q:4,25|28,28|30,30|40,42|61,72|74,84|86,86|88,88|90,96|99,106|109,109|111,113|130,135 ????HHHHHHHHHHHTTSHHHHHHHH--T?S---------GGG------------------TSTHHHHHHHHG-GGGGSTTGGGG?S?T-HHHHHHH--HHHHHHHH??B?SSS---------------?BGGGTT??????? 3FBN|B PF05683.7_Fumerase_C_seed 72 258 !Q:0,63|65,66|72,72|74,75|77,78|84,85|88,88|99,100|111,111|116,118|120,121|123,124|127,127|131,131|133,134|136,138|149,150|152,152|168,168|170,170|178,180|190,190|198,198|200,201|218,218|220,220|223,223|244,244|248,248|252,257 Q:64,64|67,71|73,73|76,76|79,83|86,87|89,98|101,110|112,115|119,119|122,122|125,126|128,130|132,132|135,135|139,148|151,151|153,167|169,169|171,177|181,189|191,197|199,199|202,217|219,219|221,222|224,243|245,247|249,251 ???????????---------?-----------?------------------------------?E--EEEES-S??H--HHHHH??TT?EEEEEEEEEE??HHHHHHHHHH-HHHT???S--S??TT?EEE?B??E---EESSSEEEEE??B?BGGGGTTTHHHHHHH?S?EEEEEBS???HHHHHHHTT-TEEEEEE?S?-SSTTGGGGEEEEEEEE?G-GG?TTTSEEEEEEEEEEEEEEEE?TTS?BTT----?? 2ISB|A PF05685.7_Uma2_seed 170 310 !Q:4,4|9,14|25,26|30,30|34,39|42,44|50,50|60,61|65,66|70,70|72,72|75,76|80,80|82,82|84,85|88,92|94,108|111,111|114,115|125,130|135,135|138,149|155,156|159,160|167,168|172,174|178,178|182,198|204,210|212,212|216,216|222,227|230,241|247,253|258,258|261,273|275,276|279,283|287,287|292,292|298,298|300,300|302,305|308,308 Q:0,3|5,8|15,24|27,29|31,33|40,41|45,49|51,59|62,64|67,69|71,71|73,74|77,79|81,81|83,83|86,87|93,93|109,110|112,113|116,124|131,134|136,137|150,154|157,158|161,166|169,171|175,177|179,181|199,203|211,211|213,215|217,221|228,229|242,246|254,257|259,260|274,274|277,278|284,286|288,291|293,297|299,299|301,301|306,307|309,309 HHHH-HHHH------HHSTTEEEEE?-TTS?EEE------EE??-HHHHH-HHHHHHHHH--HHH--HHH-H?SE--EEE?T-T??EE?----T---------------TS?EE??SEEEEEHHH------HHTS?HH------------HHHSS-?BS??SEEEEE??TTS?--HHH-HHH-----------------HHHHH-------H-HTT?SEEEE------EE------------TTTTE-------EEEE?TT-------------S??EE-----EES?SEEE?TTTST-T?E----EE?G 3OT2|A PF05690.9_ThiG_seed 28 255 !Q:8,9|13,14|16,16|31,32|42,58|68,68|71,72|90,94|96,97|102,103|106,106|110,111|113,113|129,129|136,136|138,138|149,150|156,156|162,166|168,168|179,180|183,183|189,191|204,204|240,254 Q:0,7|10,12|15,15|17,30|33,41|59,67|69,70|73,89|95,95|98,101|104,105|107,109|112,112|114,128|130,135|137,137|139,148|151,155|157,161|167,167|169,178|181,182|184,188|192,203|205,239 EETTEEES??EEE??S?SSSHHHHHHHHHHS??SEEEEEGGG?????????????????TTTSEEEEE?TT??SHHHHHHHHHHHHTTTT-----S??EEEE??BS?TTT??B?HHHHHHHHHHHHTTT?EEEEEE?S?HHHHHHHHHS??SEEEE?SSSTT?????S?HHHHHHHHHH?-SS?BEEES???SHHHHHHHHHHT?SEEEESHHHHTSSSHHHHHHHHHHHHHHHHHHHHH???????-??????? 1XM3|A PF05693.8_Glycogen_syn_seed 7 687 !Q:8,9|37,38|49,50|52,52|58,58|76,77|88,89|95,95|115,119|122,122|146,156|159,160|170,170|180,181|192,192|203,203|205,205|213,214|224,224|238,238|259,260|264,267|269,273|301,303|305,305|319,319|344,350|358,361|366,366|406,408|412,414|420,420|435,437|440,443|455,455|466,469|472,472|479,480|482,484|487,487|491,493|501,501|506,508|514,514|525,526|544,544|557,557|562,562|580,581|620,620|625,625|632,635|642,686 Q:0,7|10,36|39,48|51,51|53,57|59,75|78,87|90,94|96,114|120,121|123,145|157,158|161,169|171,179|182,191|193,202|204,204|206,212|215,223|225,237|239,258|261,263|268,268|274,300|304,304|306,318|320,343|351,357|362,365|367,405|409,411|415,419|421,434|438,439|444,454|456,465|470,471|473,478|481,481|485,486|488,490|494,500|502,505|509,513|515,524|527,543|545,556|558,561|563,579|582,619|621,624|626,631|636,641 EEETTSSS??SHHHHHHHHHHHHHHHHHTTSEEEEEE??TTTHHHHEEE??S?STTSS?STTHHHHHHHHHHHHHT??EEEEEESSTT??EEEEE?SGGGGGGHHHHHHHHHHHT?????SS?HHHHHHHHHHHHHHHHHHHHHHH??---------SB??EEEEESGGG?THHHHHHHS??SSEEEEEESS?HHHHHHTTSS?S?HHHHGGG??HHHHHHHTT?HHHHHHHHHHHHH?SEEEESSHHHHHHHHHHTSS??SEE????B?????SSTTHHHHHHHHHHHHHHHHHHHHTTT???S?GGGEEEEEEESSS?TTTTTHHHHHHHHHHHHHHHHHTT?----??EEEEEEE????EEEE?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSTT?-?SSS???GGGTS?HHHHHHHHHHHHHH???TT????SBSEEETTGGG?HHHHHHHHTT????TT?SEEEEE??S???TT?SSS???HHHHHHH?SEEE???SSBSS?HHHHHHHHTT??EEEETTBHHHHHHHTTS?HHHHGGGTEEEE?SSSS?HHHHHHHHHHHHHHHHH??HHHHHHHHHHHHHHGGGGBHHHHHHHHHHHHTTHHHHH?HHHH-HHTTSS????SSSSTT????????????????????????????????????????????? 3RSZ|A PF05694.6_SBP56_seed 28 527 !Q:0,3|6,7|15,15|18,20|29,29|34,39|46,47|62,62|66,68|70,72|76,78|86,88|91,95|97,97|107,108|114,115|117,117|121,121|128,128|137,137|147,147|150,151|159,160|165,167|169,171|177,177|181,182|187,188|191,191|194,199|212,212|214,216|223,225|233,234|236,237|256,257|269,269|274,275|288,289|298,298|301,304|307,307|309,309|318,319|322,325|328,330|333,347|355,360|364,364|368,368|385,385|391,391|399,399|405,405|407,424|428,433|435,438|442,442|452,455|464,464|467,472|480,480|483,484|486,486|496,498|500,500|503,507|518,519|523,525 Q:4,5|8,14|16,17|21,28|30,33|40,45|48,61|63,65|69,69|73,75|79,85|89,90|96,96|98,106|109,113|116,116|118,120|122,127|129,136|138,146|148,149|152,158|161,164|168,168|172,176|178,180|183,186|189,190|192,193|200,211|213,213|217,222|226,232|235,235|238,255|258,268|270,273|276,287|290,297|299,300|305,306|308,308|310,317|320,321|326,327|331,332|348,354|361,363|365,367|369,384|386,390|392,398|400,404|406,406|425,427|434,434|439,441|443,451|456,463|465,466|473,479|481,482|485,485|487,495|499,499|501,502|508,517|520,522|526,526 ????TT??SSHHHHH-TS???SEEEEEEE?TTTT???-??EEEEEE??TTSTTTTSEEEEEE?SSS???B???EES??-GGGGSTT-??TT?---?S?EEEEEBTTT??EEEEE??S?TTS?EEEEEE?HHHHHHHH?EEEEEEEEE?SS?-EEEEEEE--ETTS--?S??-EEEEE?TTT??EEEE??SB?TT??????EEEETTTTEEEE?B???HHHHTT???TTTHHHH--S??EEEEEETTTTEEEEEEES?-TTEEEEEEEEE?SSTT??EEEEEEEEETTT??EEEEEEEE-ET----TE-E-EEEEEEEE??EE??--SS-??GG---------------GGGGTEE??????EEE?TTS?EEEEEETTTTEEEEEE?SSTTS?EEEEEEE?BTTTT?B----------------??TTS?--???S????EEE?TTSSEEEEE????HHHHHHHS-TT??--??EEEEEEE?TT--S?EEEEEEEEE---E?TT-----SEEEEEEETT??TTT???S 2ECE|A PF05697.8_Trigger_N_seed 152 214 !Q:0,0|6,6|8,9|15,15|22,22|40,43|45,47|51,51|53,55|57,60|62,63|66,72|80,80|82,82|94,96|106,109|111,114|116,118|121,121|123,127|130,141|146,151|155,157|160,162|170,178|181,182|185,188|191,192|196,202 Q:1,5|7,7|10,14|16,21|23,39|44,44|48,50|52,52|56,56|61,61|64,65|73,79|81,81|83,93|97,105|110,110|115,115|119,120|122,122|128,129|142,145|152,154|158,159|163,169|179,180|183,184|189,190|193,195|203,213 ?EEEEE-E-?STTEE-EEEEEE?HHHHHHHHHHHHHHHHT----T???TTS?S---S?-??H--HH-------HHHHHHH-H-HHHHHHHHHHH---HHHHHHHHH----T----T??-BS-S??---EE------------EEEE----??TTS?--EE---EEEEEEB????---??TT-?TT?---EE--ESS??-????THHHHHHHHHH 3GTY|X PF05698.9_Trigger_C_seed 55 181 !Q:0,0|14,14|37,45|57,60|69,72|74,75|79,87|92,92|119,122|136,136|140,144|155,155|160,162 Q:1,13|15,36|46,56|61,68|73,73|76,78|88,91|93,118|123,135|137,139|145,154|156,159|163,180 ?HHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHH???---???HHHHHHHHHHH----HHHHHTTT----T??TTS---------STTS?GGGTHHHHHHHHHHHHHHHHHHHHTT????HHHHHHHHHHHHT-TSS----?HHHHHHHHHH?HHHH---HHHHHHHHHHHHHHHHHT 3GTY|X PF05699.9_Dimer_Tnp_hAT_seed 49 98 !Q:7,12|15,25|32,34|54,54|56,56|61,62|70,71|77,77|81,83 Q:0,6|13,14|26,31|35,53|55,55|57,60|63,69|72,76|78,80|84,97 HHHHHHT??????TT---------??HHHHHH---HTTTTSHHHHHHHHHHHTS?S?TTTT--HHHHHHT--HHHHH?TTT???HHHHHHHHHHHHHH 2BW3|A PF05706.7_CDKN3_seed 2 168 !Q:0,21|25,28|33,33|38,38|40,40|45,47|50,51|56,56|58,58|71,72|77,77|79,79|88,88|100,100|105,108|112,114|133,134|139,139|158,158|162,162 Q:22,24|29,32|34,37|39,39|41,44|48,49|52,55|57,57|59,70|73,76|78,78|80,87|89,99|101,104|109,111|115,132|135,138|140,157|159,161|163,167 ??????????????????????BTS????EEEE?GGGT?S?EEEE???TT??BTTB?B?HHHHHHHHHHHT??EEEE?S?HHHHHHTT?TTHHHHHHTTT?EEEE????TTS???HHHHHHHHHHHHHHHHTT??EEEE?SSSSSHHHHHHHHHHHHH?SSS?HHHHH 2DXP|A PF05707.7_Zot_seed 17 315 !Q:0,0|6,7|20,20|24,24|29,33|35,35|38,41|45,47|51,52|54,61|65,66|68,69|73,73|76,77|80,105|115,115|118,120|127,127|137,138|142,144|146,146|148,207|211,211|222,222|230,230|235,235|240,240|242,242|253,254|257,258|267,270|274,276|286,293|296,299|307,314 Q:1,5|8,19|21,23|25,28|34,34|36,37|42,44|48,50|53,53|62,64|67,67|70,72|74,75|78,79|106,114|116,117|121,126|128,136|139,141|145,145|147,147|208,210|212,221|223,229|231,234|236,239|241,241|243,252|255,256|259,266|271,273|277,285|294,295|300,306 -EEEEE??TTSSHHHHHHHH-HHH?GGGS??---T-TS????EEE-??TTB?-S?------?EEE--E??TTT?SS??SS?-------------------------EEGGGHHHH-TT---SGGGTT?EEEETTGGG--TSB???T-T???--------------------------------------------------------?HHH-HGGGGTTTTT?EEEEEES?GGGB?HHHH-T-TEEEEEEEEE?-SS??EEEEEESS--??SST---TTTGGGSEE--------EE????TTGGGSB?-?????? 2R2A|A PF05708.7_DUF830_seed 33 245 !Q:0,2|5,5|10,13|26,29|32,33|44,64|66,66|73,74|77,81|96,99|103,103|112,117|134,135|137,137|140,141|144,164|169,169|183,186|188,189|196,198|212,217|219,221|224,224|227,230|237,237|245,245 Q:3,4|6,9|14,25|30,31|34,43|65,65|67,72|75,76|82,95|100,102|104,111|118,133|136,136|138,139|142,143|165,168|170,182|187,187|190,195|199,211|218,218|222,223|225,226|231,236|238,244 ???TT?EEEE???-STTHHHHHHHHT----SS??EEEEEEEETT---------------------E-EEEEEE--SS-----SEEEEEHHHHHHTS----GGG?EEEEEETT?---??HHHHHHHHHHHGGGTT??B?TT??SS---------------------SSSB?HHHHHHHHHHHHH????S??EEGGGS???SHHHHHHHHHHHT------T???TT?EE?--?HHHHHT?TTEEEEE- 2IF6|A PF05709.6_Sipho_tail_seed 71 848 !Q:9,9|12,14|16,17|22,23|25,25|28,28|30,32|34,34|38,40|43,45|55,57|59,62|67,77|82,82|91,94|97,98|107,146|149,149|159,161|164,175|177,177|186,186|190,190|195,350|358,358|361,361|363,380|385,385|387,397|400,400|402,403|405,409|414,414|416,418|420,421|423,428|437,441|451,759|764,767|771,771|773,776|779,780|783,783|787,791|794,795|797,813|815,815|823,830|835,835|839,839|844,844|847,847 Q:0,8|10,11|15,15|18,21|24,24|26,27|29,29|33,33|35,37|41,42|46,54|58,58|63,66|78,81|83,90|95,96|99,106|147,148|150,158|162,163|176,176|178,185|187,189|191,194|351,357|359,360|362,362|381,384|386,386|398,399|401,401|404,404|410,413|415,415|419,419|422,422|429,436|442,450|760,763|768,770|772,772|777,778|781,782|784,786|792,793|796,796|814,814|816,822|831,834|836,838|840,843|845,846 TEEEEEEES?SS???E--EEEE??T-TS?S--?E-EEE---EE???EEEEEEEEE???S----SHHH-----------HHHH-HHHHHHHH--??SS?-EEEEETTS----------------------------------------TT?EEEEEEEEE---EE?---???--???E-EEEEEEEE-EEE-EEEE------------------------------------------------------------------------------------------------------------------------------------------------------------EEEEEEE?SS?E------------------EEEB?S-----------SS?B??E-----EEEE?S---S??S?-----EEEEEEET-----TEEEEEEEE???-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?SSSE----EEE?S----SS??EE?TTS??-??TT??S?-----------?????B?BTSEEEE--------EESS?EEE-EEEE-EE? 4DIV|S PF05711.6_TylF_seed 16 273 !Q:0,3|22,23|25,56|64,64|66,66|70,70|72,72|94,96|102,103|121,122|124,125|131,131|134,134|136,139|143,143|150,151|160,164|177,178|188,188|196,200|207,209|236,236|239,239|255,256|258,259|262,262|266,266|271,272 Q:4,21|24,24|57,63|65,65|67,69|71,71|73,93|97,101|104,120|123,123|126,130|132,133|135,135|140,142|144,149|152,159|165,176|179,187|189,195|201,206|210,235|237,238|240,254|257,257|260,261|263,265|267,270 ????HHHHHHHHHHHHHTTTTT??B?-------------------????????????HHHHHTT?S?BSS?S?SSHHHHHHHHHHHHHHHHHTT???EEEEE??TTSHHHHHHHHHHHHTT??S??EEEEE?SS?S????TTS?HHHHHH?-GGGGHHHH???--HHHHHHHHHHTT??STTEEEEES?HHHHSTT?????EEEEEE???SHHHHHHHHHHHGGGEEEEEEEEESS?TT?HHHHHHHHHHHHHTT??S??EE?SSS?EEEE?? 4GF5|A PF05712.8_MRG_seed 33 428 !Q:0,47|65,68|71,71|74,75|78,78|90,95|97,99|106,145|148,148|158,159|171,172|176,177|190,358|360,363|368,369|380,382|391,394|417,418|422,423 Q:48,64|69,70|72,73|76,77|79,89|96,96|100,105|146,147|149,157|160,170|173,175|178,189|359,359|364,367|370,379|383,390|395,416|419,421|424,427 ??--------------------------------??????---?????HHHHHHHHHHHHHHHTS?--?EE?SS?-SS?HHHHHHHHHHH------H---HHHHHS???????????????????????----------------?TT?HHHHHHHHH--HHHHHHHHHHH--HHS??GGGHHHHHHHHH??------------------------------------------????--------------------------------------------------------------------------------------------------------------------?????S????GGGT??HHHHHHHHHH---HHHHHHHS?-??HHHHHHHHHHHHHHHHHHHHTH--HHH??GGGE 2LKM|B PF05714.6_Borrelia_lipo_1_seed 18 240 !Q:8,11|15,24|39,47|51,54|65,66|69,71|74,74|77,77|80,80|95,95|98,98|100,100|103,103|114,114|159,159|162,162|195,195|198,198|202,202|212,217|221,221|236,236 Q:0,7|12,14|25,38|48,50|55,64|67,68|72,73|75,76|78,79|81,94|96,97|99,99|101,102|104,113|115,158|160,161|163,194|196,197|199,201|203,211|218,220|222,235|237,239 HHHHHHHH----HHH----------HHHHHHHHHHHHHT------???TTG----GGTIIIIITT??SS---TT?SS?TT-SGGGHHHHHHHHHT-TT-T?HH-HHHHHHHHHH-HHHTSTTTHHHHHHHHHTTHHHHHHHHHHHHHHHHTTGGGGGGS?HH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?HH-HHH?HHHHHHHHH------HTS?HHHHHHHHHHHHHH-HHH 4BL4|A PF05719.6_GPP34_seed 88 454 !Q:9,10|13,13|18,19|21,23|30,31|49,57|64,64|74,77|79,80|82,104|106,107|113,116|122,127|130,133|135,139|150,150|152,153|161,163|165,165|170,172|176,178|183,183|187,188|192,193|195,195|198,201|205,207|209,211|214,217|237,242|246,279|282,282|292,298|307,307|309,309|315,315|319,319|326,346|358,368|374,375|378,380|382,429|440,445 Q:0,8|11,12|14,17|20,20|24,29|32,48|58,63|65,73|78,78|81,81|105,105|108,112|117,121|128,129|134,134|140,149|151,151|154,160|164,164|166,169|173,175|179,182|184,186|189,191|194,194|196,197|202,204|208,208|212,213|218,236|243,245|280,281|283,291|299,306|308,308|310,314|316,318|320,325|347,357|369,373|376,377|381,381|430,439|446,453 HHHHHHHHT??SS-SGGG--S???HHHHHH--HHHHHHHHHHHTTSEEE???------GGGGGS?GGGSBEEES--??S??S----------------------?H--HHHHH----HHHHH------TS?-??B-----HHHHHHHTTT?S??GGGGGGS???H-HHHH---HHH---HHHT-TSB??EEE--E?SS?---EEE---E??-BS?---HHHHHHHHHHHHHHHTSSS??????SSS?---------------------------------TT?TTHHHHHHH-------HHHHHHHH-T?SGGGG-TTS?HHHHHH---------------------HHHHHHHHHHH-----------TSSSS??TT???S------------------------------------------------SSSSTTHHHH------HHHHHHSS 3KN1|A PF05721.8_PhyH_seed 39 313 !Q:11,14|17,17|19,19|36,39|45,46|66,66|75,75|80,80|84,84|88,89|100,100|105,105|109,109|115,115|127,127|133,148|154,157|159,161|166,167|169,171|175,175|181,188|192,194|197,197|201,204|211,211|213,213|218,218|222,222|225,225|229,230|237,238|242,244|246,264|269,274|278,278|282,282|284,284|287,287|295,296|300,301|303,303|307,311 Q:0,10|15,16|18,18|20,35|40,44|47,65|67,74|76,79|81,83|85,87|90,99|101,104|106,108|110,114|116,126|128,132|149,153|158,158|162,165|168,168|172,174|176,180|189,191|195,196|198,200|205,210|212,212|214,217|219,221|223,224|226,228|231,236|239,241|245,245|265,268|275,277|279,281|283,283|285,286|288,294|297,299|302,302|304,306|312,312 HHHHSEEEETT----SS?H-HHHHHHHHHHHHHHHT????HHHHS??SSHHHHHHHHHHHHHHHHT?TTSEEEEE?GGGB?SSS?BSS-?GGGTEEEEEE?HHHH?HHH-HHHHT?HHHHHHHHHTT?SSEEE----------------EEEEE----E???TTTB??E---EEE?GGGTS?-------EES---SS?EEE----EEEESS?B?TTTT?EEE?TT?SSS??SEEEEE??SSS???E-------------------EEEE??????GGG?EEE?B?TT?EEEEETT??EEE??B?SSS--???E 3EMR|A PF05724.6_TPMT_seed 12 238 !Q:0,1|13,14|17,18|21,22|36,37|39,39|46,46|49,49|60,60|66,66|68,68|81,83|89,91|97,97|113,113|121,124|138,138|159,160|168,169|173,176|179,182|184,188|197,197|208,208|211,213|215,216|223,223|225,226|234,234|237,237 Q:2,12|15,16|19,20|23,35|38,38|40,45|47,48|50,59|61,65|67,67|69,80|84,88|92,96|98,112|114,120|125,137|139,158|161,167|170,172|177,178|183,183|189,196|198,207|209,210|214,214|217,222|224,224|227,233|235,236 ??HHHHHHHHHTT??TT??TT??HHHHHHHHHHTTT??S?EEEETT?TT?THHHHHHTTT?EEEEE?S?HHHHHHHHHHTT??-EEEEE--?TTSTT?EEEEETTSSEEEEES?GGGGGGS????EEEEEESSSTTTS?GGGHHHHHHHHHTTEEEEEE--EEEEEEE??TTT??-?SS????H-----HHHHHHHT-TTEEEEEEEE-EE???G--GGGGGT?S??EEEEEEE-EE? 3SM3|A PF05726.8_Pirin_C_seed 34 138 !Q:6,6|9,9|15,17|20,20|28,30|33,34|36,46|50,50|54,59|63,63|71,74|76,76|83,84|86,86|89,89|92,95|102,105|107,108|133,135 Q:0,5|7,8|10,14|18,19|21,27|31,32|35,35|47,49|51,53|60,62|64,70|75,75|77,82|85,85|87,88|90,91|96,101|106,106|109,132|136,137 EEEEEE?TT?EEEEE-??TT?EEEEEEE---ES?-E-----------EES?TTS-----?EEE?TTEEEEE?---S?SEEEEE??S-SS?EE----EEEEEE????S??EEETTEEESSHHHHHHHHHHHHTT--?TT 1J1L|A PF05728.7_UPF0227_seed 9 209 !Q:5,6|9,11|14,14|28,28|35,39|60,63|85,86|88,89|94,95|106,106|111,111|115,116|121,121|132,133|136,149|151,151|163,163|167,167|169,170|188,190|193,193 Q:0,4|7,8|12,13|15,27|29,34|40,59|64,84|87,87|90,93|96,105|107,110|112,114|117,120|122,131|134,135|150,150|152,162|164,166|168,168|171,187|191,192|194,208 EEEEE??TT?-?TT?HHHHHHHHHHHHH?TTSEEE?????SSHHHHHHHHHHHHHHHTTS?---EEEEEETHHHHHHHHHHHHTT??E--EEES??SSHHHHGGGG?EEEE?TTT??EEEE?HHHHHHHHTT??SS-------------?S?GGGEEEEEETT?SSS?H--HHHHHHTTTSEEEEESS?-?TT?TTGGGGHHHHHHHHT 4FLE|A PF05729.7_NACHT_seed 26 229 !Q:27,28|33,35|37,37|48,49|51,60|70,71|73,73|76,77|79,90|106,119|124,124|128,129|133,133|135,151|159,160|164,165|179,181|186,186|190,205|209,212|221,221|226,226 Q:0,26|29,32|36,36|38,47|50,50|61,69|72,72|74,75|78,78|91,105|120,123|125,127|130,132|134,134|152,158|161,163|166,178|182,185|187,189|206,208|213,220|222,225|227,228 SSEEEEESTTSSHHHHHHHHHHHHHHT??SGGG---G?SEEEEEETTS??S---------?HHHHHHHHH??S?TT??H------------HHHHHHHHHHGGGEE--------------EEEE?GGG??TTT?H-----------------HHHHHHH??TTT??EEEEEEETTTHHH---HTTT?SEE----------------EEE????HHHHHHHH-HHHS?HH 1PV4|A PF05731.6_TROVE_seed 9 569 !Q:2,2|6,6|11,12|20,27|29,32|36,36|40,41|45,45|65,65|81,81|84,84|98,98|101,101|107,124|134,135|147,164|174,175|177,177|193,193|204,207|209,209|225,227|231,246|258,281|292,295|314,316|328,370|375,375|381,393|404,407|425,425|428,428|431,431|441,441|450,451|467,535|537,540|546,549|559,559|561,568 Q:0,1|3,5|7,10|13,19|28,28|33,35|37,39|42,44|46,64|66,80|82,83|85,97|99,100|102,106|125,133|136,146|165,173|176,176|178,192|194,203|208,208|210,224|228,230|247,257|282,291|296,313|317,327|371,374|376,380|394,403|408,424|426,427|429,430|432,440|442,449|452,466|536,536|541,545|550,558|560,560 EE?TTS?EEEE??HHHHHHH--------H----HHH?STT??SSS?HHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHT?SS?SHHHHHHHHHHTS-SS?HHHHH------------------HHHHHHHHH??SHHHHHHHHHH------------------HHHHHHHTT??S?SHHHHHHHHHHHHTS?HHHHHHHHHH?---S-EETTEEHHHHHHHHT???SSH----------------HHHHHHHHHHH?-----------------------HHHHHHHTTT????HHHHHHHHHHHHHHHGGG???HHHHHHHHHHH??----------------------------------------?GGGS?TGGGG------------?HHHHHHHHHT--??HHHHHHTHHHHHHTTTT?TT?HH-HHHHHHHHT?HHHHHHTT??HHHHHHHHHHHHHTB??-???--------------------------------------------------------------?B????HHHHH----HHHHHHHHH-S???????? 1YVP|A PF05733.6_Tenui_N_seed 12 255 !Q:0,0|12,19|33,33|35,36|42,42|45,46|52,54|73,78|80,80|89,89|105,106|108,109|112,113|116,118|139,140|146,146|154,154|158,159|171,172|176,180|203,203|207,207|209,210|213,217|233,233|237,237|241,244 Q:1,11|20,32|34,34|37,41|43,44|47,51|55,72|79,79|81,88|90,104|107,107|110,111|114,115|119,138|141,145|147,153|155,157|160,170|173,175|181,202|204,206|208,208|211,212|218,232|234,236|238,240|245,254 ?HHHHHHHHHHS???-----HHHHHHHHHHHSB?S??HHHHH-HH--HHHHH---GGGHHHHHHHHHHHHHHT?-----S?HHHHGGGS?HHHHHHHHHHHHHHT??S--SS??TT???HHHHHHHTHHHHHHHHHHHG--GGSSS?HHHHHHH-STT??GGGSSGGGGGG??TTS?----HHHHHHHHHHHHHHHHHHHHHH?TTS?S??HH-----HHHHHHHHHHHHHHT?SSS?HHH----HHHHHHHTTS 4J4V|A PF05735.7_TSP_C_seed 10 203 !Q:0,4|17,17|19,20|43,44|47,49|72,72|75,75|77,78|82,83|86,86|89,89|96,96|99,99|113,113|124,124|127,131|134,134|147,147|164,166|169,170|184,184|186,186|197,198|200,202 Q:5,16|18,18|21,42|45,46|50,71|73,74|76,76|79,81|84,85|87,88|90,95|97,98|100,112|114,123|125,126|132,133|135,146|148,163|167,168|171,183|185,185|187,196|199,199 ?????EEEETTTTEEEE?S??SSEEEEEEEEESSEEEEEEEEE??SS???EEEEEEEEEETTEEEEEEEESS?EE?S??SSS??EE?SS?EEEEEE?SS?TTHHHHHHHHSSS?BTTTEEEEEE?TT?????TT?EEEEEEEEEGGG-TEEEEEEEETTEEEEE???EE??SSSSEEEEEEEES?S?EEEEEEEEEE??S?-? 3FBY|A PF05737.7_Collagen_bind_seed 15 159 !Q:0,1|9,10|13,13|16,17|26,26|29,31|33,33|36,36|44,44|63,63|67,67|78,83|88,88|104,104|106,106|124,124|127,134|145,145|150,151|157,158 Q:2,8|11,12|14,15|18,25|27,28|32,32|34,35|37,43|45,62|64,66|68,77|84,87|89,103|105,105|107,123|125,126|135,144|146,149|152,156 ??SEEEEEE??TT?TT--EEEEEEEE?TT???B-SS?EEEEEEE?SSEEEEEEEEEEEEEETT?EEE?SSSHHHHHHH------HSTT?EEEEETTTTEEEEEE?H-HHHTTEEEEEEEEEEES?TT??------EEEEEEEEEE?BTTS??EEEEE?? 1AMX|A PF05738.8_Cna_B_seed 135 105 !Q:0,1|3,3|13,13|18,38|42,43|54,60|64,64|72,74|78,83|89,89|91,91|94,98|100,100|104,104 Q:2,2|4,12|14,17|39,41|44,53|61,63|65,71|75,77|84,88|90,90|92,93|99,99|101,103 ??S?EEEEEETTS?EEEE---------------------EEE??TTSEEEEEEE------?SEE-EEEEEEE-??TTB??????EEEEE?S?EE-----E?SSS? 4JDZ|B PF05739.14_SNARE_seed 105 67 !Q:54,55|57,58 Q:0,53|56,56|59,66 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--H--HHHHHHHH 3B5N|B PF05741.8_zf-nanos_seed 36 91 !Q:0,0|6,18|21,22|30,30|32,46|48,48|52,55|57,58|62,62|65,67|71,73|77,83|87,87|90,90 Q:1,5|19,20|23,29|31,31|47,47|49,51|56,56|59,61|63,64|68,70|74,76|84,86|88,89 ?HHHHH-------------TT??HHHHTSB?S---------------B?TTS?---B??TTG-GG???TTT???GGG?----??GGG?TT? 3ALR|A PF05743.8_UEV_seed 23 152 !Q:13,16|22,23|27,28|32,32|36,37|47,47|50,50|52,52|61,62|68,73|75,77|81,83|86,93|95,96|99,99|102,102|107,109|111,111|116,117|119,120|122,129|140,143|149,149 Q:0,12|17,21|24,26|29,31|33,35|38,46|48,49|51,51|53,60|63,67|74,74|78,80|84,85|94,94|97,98|100,101|103,106|110,110|112,115|118,118|121,121|130,139|144,148|150,151 HHHHHHHHHHHHS----SEEEE??EEE?-TTS?EEE??EEEEEEEEE?SS?E-EEEEEEEE??SSSSS------S???EEE???TT?------?B??BT-TB?SSSB?-?S?TTTT??S--S???-----HHHHHHHHHH----HHHHS?SB 3R3Q|A PF05746.10_DALR_1_seed 104 182 !Q:13,15|22,25|32,38|40,42|45,46|48,48|71,81|83,83|103,105|107,114|116,120|124,135|137,137|142,152|175,178|180,181 Q:0,12|16,21|26,31|39,39|43,44|47,47|49,70|82,82|84,102|106,106|115,115|121,123|136,136|138,141|153,174|179,179 HHHHHHHHHHHHH---HHHHTT????HHHHHH-------H???SS??H-HHHHHHHHHHHHHHHHHHHHHT-----------T?THHHHHHHHHHHHHHHHHH---H--------H?---?STT------------S?TTHH-----------HHHHHHHHHHHHHHHHHHHHTT????S?? 1BS2|A PF05748.6_Rubella_E1_seed 2 496 !Q:0,16|22,23|27,27|30,30|34,34|54,55|67,68|70,71|81,81|103,103|107,107|111,111|116,117|120,120|128,129|136,136|140,141|144,147|151,152|163,164|168,168|193,193|196,197|210,216|223,228|237,238|246,246|259,259|262,267|272,273|276,276|282,284|295,295|300,300|308,309|316,316|325,325|329,335|343,349|351,352|354,355|369,369|377,377|395,395|404,406|408,408|411,411|422,422|428,428|441,441|447,495 Q:17,21|24,26|28,29|31,33|35,53|56,66|69,69|72,80|82,102|104,106|108,110|112,115|118,119|121,127|130,135|137,139|142,143|148,150|153,162|165,167|169,192|194,195|198,209|217,222|229,236|239,245|247,258|260,261|268,271|274,275|277,281|285,294|296,299|301,307|310,315|317,324|326,328|336,342|350,350|353,353|356,368|370,376|378,394|396,403|407,407|409,410|412,421|423,427|429,440|442,446 ---------------??EEEEE??STT?EE?SSS?EEEEEEEEEEEEEEEEEEE??EEEEEEEEESS??S??STTTTTTTS?HHHHHHHHTSEEEEEEEEEEE?BSS?SSS?BGGG??TT?HHHHHHS??SSEEEE?TTS??TT????SSS??EEEEEEEEEE??GGG?EEEEEEEEEEEEEEEEETTEEEEE?SS??EEEETTEEEEEE???????EEEEEE??????EEEEEESS??TTTTTTT?GGGSEEETTSSS?BS??????EEEE??TT?GGGGS???TTEEEEEEEE?SSTT?EEEEEEE??GGGEEE?HHHHHHHH?BSS???????EEEEEES???????B??S??EEEEEEEESSSSS?EEEEEEE?SSSBEEEEETTEEEEEE?SEEEEEEE???S?SS?EEESSSSEEE?EEEEE?HHHHHTTTEEES?EEEEE??????????????????????????????-------------?????? 4B3V|A PF05757.6_PsbQ_seed 18 241 !Q:0,78|80,80|83,110|113,120|123,126|129,130|144,144|155,157|172,173|186,187|199,199|217,217|240,240 Q:79,79|81,82|111,112|121,122|127,128|131,143|145,154|158,171|174,185|188,198|200,216|218,239 --------------------------------------------------------------------?---------?S?EE????????????????????????????TT?------?EE????HH--HHHHHHHHHHHHH-HTTHHHHHTT?--HHHHHHHHHHHHHH--HHHHHHHHHHHS?-HHHHHHHHHHH-HHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHH? 1VYK|A PF05761.9_5_nucleotid_seed 21 571 !Q:0,0|5,5|11,12|17,18|26,26|45,45|48,49|54,54|56,59|63,64|67,67|80,80|83,83|87,88|98,98|110,110|112,113|116,116|119,128|131,134|155,155|159,183|195,195|227,227|234,235|250,250|256,256|259,259|272,272|282,287|292,292|299,300|308,311|316,316|320,320|323,323|326,343|345,347|350,360|364,365|375,377|387,387|400,401|407,407|427,428|436,492|508,509|512,513|518,518|523,523|533,533|539,539|547,547|550,550|553,561|565,570 Q:1,4|6,10|13,16|19,25|27,44|46,47|50,53|55,55|60,62|65,66|68,79|81,82|84,86|89,97|99,109|111,111|114,115|117,118|129,130|135,154|156,158|184,194|196,226|228,233|236,249|251,255|257,258|260,271|273,281|288,291|293,298|301,307|312,315|317,319|321,322|324,325|344,344|348,349|361,363|366,374|378,386|388,399|402,406|408,426|429,435|493,507|510,511|514,517|519,522|524,532|534,538|540,546|548,549|551,552|562,564 ?EESS?EEGGG??EEEE??BTTTBEE?TTHHHHHHHHHHHHHHHH-TT??GGGG-G????TTS??TT?EEETTTTEEEEE?TT?BEE--EEEETTEEE?HHHHTTTSTTS-B??TT?TT----------TB????STTHHHHHHHHHHHHHHHHT?TTS-------------------------EEETTEEEETT-EEEEHHHHHHHHHHHHHHHHHTSSHHHHHHT?HHHHEE??THHHHHHHHHHHHS-EEEEE?SS?HHHHHHHHHHHT?SSSSSSTTS--????GGGG?SEEEES??TTGGGTT??-?EEEB?TTT?SB?SS?---------------??S???TT---------??EEE??HHHHHHHTT??-GGGEEEEES?IIIIIHHHHHHH??EEEEE?TTHHHHHHHHHHTHHHHHH--HHHHHHH?????????-----------------------------------???????-?????HHHHHHHHHHHHHTT?-TT??SSEE-TTEE?HHHHHHHHH?SEEES?GGGGGGS?TT?EE?????--??GGG?????? 2XJF|A PF05768.9_DUF836_seed 48 151 !Q:6,6|9,9|14,20|29,33|38,46|54,60|66,73|87,87|103,105|110,110|112,132|134,135|141,141 Q:0,5|7,8|10,13|21,28|34,37|47,53|61,65|74,86|88,102|106,109|111,111|133,133|136,140|142,150 EEEEEE?TT?HHHH-------HHHHHHHT-----TTTT---------EEEEEEE???????TTGGG????????THHHHHHHHGGGG?EEEEEEETTTTEEEE???GGGB?T---------------------T??SGGGB?HHHHHHHHH 1J08|A PF05770.6_Ins134_P3_kin_seed 5 333 !Q:7,7|13,14|35,35|40,41|45,45|50,52|58,59|70,70|87,87|95,95|118,120|123,123|129,131|136,136|138,140|152,153|160,160|163,163|167,167|169,170|176,176|183,187|193,196|217,232|245,247|249,254|257,260|262,264|266,271|287,289|298,298|302,304|314,316|319,319 Q:0,6|8,12|15,34|36,39|42,44|46,49|53,57|60,69|71,86|88,94|96,117|121,122|124,128|132,135|137,137|141,151|154,159|161,162|164,166|168,168|171,175|177,182|188,192|197,216|233,244|248,248|255,256|261,261|265,265|272,286|290,297|299,301|305,313|317,318|320,332 GGGGGTT?EEEEE??HHHHHHHTHHHHHHHHHTTT?EEEE??TTS?SGGG???SEEEE??HHHHHHHHTT?HHHHHHHHHHHHHHHH?TTSEEES?HHHHHHTTBHHHHHHHHHHHHH---HH?BTTEE???EEEE?S???TTHHHHHHHTT??SSEEEE?SB?SST-T??EEEEE?SGGGTT?????EEEEE????TTEEEEEEEETTEEEEEEEE??????????--????EEEEGGGTSSTT???G------GG??--S???S??????HHHHHHHHHHHHHHH???EEEEEEEE?TTT-??EEEEEEEES???TT?TTHHHHHHHHHHH 1Z2N|X PF05772.7_NinB_seed 13 128 !Q:17,20|24,24|32,32|35,35|53,54|59,61|74,78|80,81|86,86|96,98|102,103|123,125 Q:0,16|21,23|25,31|33,34|36,52|55,58|62,73|79,79|82,85|87,95|99,101|104,122|126,127 EESSHHHHHHHHHHHHT????SSS?EEEEEEE?SS?HHHHHHHHHHHHHHHHH??BTTB???HHHHHHHHHHHH-----S??EEEE?SSSSSEEEE???TTT??HHHHHHHHHHHHHHHHHTT???HH 1PC6|A PF05773.17_RWD_seed 119 331 !Q:0,0|16,16|21,55|58,59|63,63|68,122|124,127|131,209|217,218|220,222|226,226|229,230|232,232|235,237|244,287|307,311|313,313|315,316|327,328 Q:1,15|17,20|56,57|60,62|64,67|123,123|128,130|210,216|219,219|223,225|227,228|231,231|233,234|238,243|288,306|312,312|314,314|317,326|329,330 ?HHHHHHHHHHHHHHH?SSSE-----------------------------------EE??SSS?EEEE??-----------------------------------------------------B????TTS???----------------------------------------------------------------------------BEEEEEE??S---STT-TS??E-EE---EEEESS??------------------------------------------HHHHHHHHHHHHHHHHHHT-----T-S??HHHHHHHHHH--HH 2EBK|A PF05775.7_AfaD_seed 10 111 !Q:2,2|4,4|6,8|11,11|16,17|20,21|24,24|26,26|30,32|34,35|39,39|43,44|47,48|53,53|56,59|64,64|67,69|73,74|78,79|85,86|90,92|95,97|103,110 Q:0,1|3,3|5,5|9,10|12,15|18,19|22,23|25,25|27,29|33,33|36,38|40,42|45,46|49,52|54,55|60,63|65,66|70,72|75,77|80,84|87,89|93,94|98,102 SS?S?S???SS?EEEE??EE??SS?S?EEE???S??STT?SSS??EE-?SSSS?EE????TTSS?EE???SSS??EEE??SSSEE??EEE???SS???SEEEE???????? 2FVN|A PF05778.7_Apo-CIII_seed 6 70 !Q:0,1|5,5|65,65|68,69 Q:2,4|6,64|66,67 ??TTS?THHHHHHHHHHHGGGHHHHHHGGGGGGGHHHHHHHTTTTTTHHHHHHHHHHHHTTGGGS?SS?? 2JQ3|A PF05785.7_CNF1_seed 10 332 !Q:0,0|9,11|19,19|28,37|40,41|48,49|52,52|58,58|60,62|64,78|80,82|94,94|107,108|111,111|120,123|126,126|132,133|148,148|153,153|158,160|164,164|184,184|186,187|190,191|210,210|213,216|218,219|232,232|250,259|268,269|271,271|275,275|289,289|307,309|313,314|319,319|322,326|331,331 Q:1,8|12,18|20,27|38,39|42,47|50,51|53,57|59,59|63,63|79,79|83,93|95,106|109,110|112,119|124,125|127,131|134,147|149,152|154,157|161,163|165,183|185,185|188,189|192,209|211,212|217,217|220,231|233,249|260,267|270,270|272,274|276,288|290,306|310,312|315,318|320,321|327,330 ?HHHHHHHH---HHHHHTT?GGGGTTSB??????????SS??EEEEEE??SS?EEEEE?S???S---------------S???GGGEETTSTTT?EESEEEEETTSS??TT?TTBSHHHH????TT?EEEEE??BTEEEEEEEEEGGG?BTTB?EEEE???BSS?EEEEEEETTEEEEEEEEES-S??TT?-TTTHHHHHHHHHHHHHTT?SS????S??SHHHHHHHHHHH?SEEEEEEEEBTTBGGGS?????-----TTEEEEEE--E-ESS?SSSEEEEEEEEEE-EETTEEEEEEEEEEEEE?--TTS??EEEE-EE-----EEEE? 1HQ0|A PF05787.8_DUF839_seed 15 807 !Q:0,1|3,9|11,15|18,18|20,21|34,34|36,36|40,44|48,50|58,59|70,70|73,94|97,101|104,104|111,114|120,140|143,143|146,147|168,168|170,171|175,175|178,178|181,181|184,184|187,213|223,224|231,231|235,236|238,248|250,251|255,255|259,261|269,269|273,273|279,279|284,286|288,288|290,290|292,293|295,302|304,307|315,316|319,319|322,324|328,332|340,340|342,349|357,357|362,362|365,365|367,368|370,372|379,380|382,382|384,386|391,391|396,396|404,407|412,412|422,423|426,426|428,431|449,461|465,470|479,480|483,538|542,542|545,547|551,553|568,568|573,575|578,578|585,585|589,595|601,602|605,605|610,625|628,635|640,641|647,647|658,663|666,666|677,679|686,686|691,692|695,696|700,701|703,703|710,710|713,714|720,720|722,725|728,750|755,756|758,758|760,762|767,767|771,772|778,778|780,781|784,784|792,792 Q:2,2|10,10|16,17|19,19|22,33|35,35|37,39|45,47|51,57|60,69|71,72|95,96|102,103|105,110|115,119|141,142|144,145|148,167|169,169|172,174|176,177|179,180|182,183|185,186|214,222|225,230|232,234|237,237|249,249|252,254|256,258|262,268|270,272|274,278|280,283|287,287|289,289|291,291|294,294|303,303|308,314|317,318|320,321|325,327|333,339|341,341|350,356|358,361|363,364|366,366|369,369|373,378|381,381|383,383|387,390|392,395|397,403|408,411|413,421|424,425|427,427|432,448|462,464|471,478|481,482|539,541|543,544|548,550|554,567|569,572|576,577|579,584|586,588|596,600|603,604|606,609|626,627|636,639|642,646|648,657|664,665|667,676|680,685|687,690|693,694|697,699|702,702|704,709|711,712|715,719|721,721|726,727|751,754|757,757|759,759|763,766|768,770|773,777|779,779|782,783|785,791|793,806 ??S???????S-----SS?B??TTEEEEEEEETT?B?STT?????TTS???HHHHTTB??SSEEEEEEEE?TT---------------------?TT-----EE-EEEEEE????HHHHS---------------------TT?SS??SHHHHHHHHHTSEEEEEEEE?T--TTS?EE?TT?TT?EE---------------------------EETTSEEEE--ESTTTT?GGG??S-----------S?-TTS?EEE???SEEEEEE?TTS?EEEEE?SGGG---G?B?S-?T--------T????HHHHHHT??SS?SS???TTT----?GGGBTTT?G--------GGGGGSS?EEEE?TT?T--T???EEEGGG??S?B???EEEE?TTSE-EEEEEEB?---SEEE?EEEEEEEEE??SS?G----GGGTTGGGSEEEEEEEE???-------???SSS?-----EEEEEEEE??TT--------------------------------------------------------STT?SG---GGT--?SSHHHHHHTHHHHH-HHTT???EE?EEEEEE?TTT?-----?EEEEE??BT-TTTS----------------TT???-----BTTB??SSBSS?EEEEEEEGGG-----?TT?SEEEEEEEEE???TTTSTT-SGGG??TT??TTT??S?EEEEEE?TT??EEEEE?S????SG-----------------------GGTT??S?E---EEEE?TTT??EEEEE-E??TT?EEEEEEE?TTSSEEEEEEESTT 4ALF|A PF05790.10_C2-set_seed 27 89 !Q:31,32|34,35|38,40|50,52|58,58|67,67|69,71|75,75|84,85|88,88 Q:0,30|33,33|36,37|41,49|53,57|59,66|68,68|72,74|76,83|86,87 EEEEEEEEEEBSGGGEEEEEEETTEEEEEEE??S??SS???EEEEEEEEE???GGGTT?EEEEEEEE?S???TTS?SEEEEEEE??EE? 1RZJ|C PF05791.6_Bacillus_HBL_seed 13 200 !Q:0,7|36,40|43,43|45,54|109,109|160,165|173,178 Q:8,35|41,42|44,44|55,108|110,159|166,172|179,199 ?????---TTTTTTHHHHHHHHHHHHHHHHHHHHHS?????TT?T----------THHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH------HHHHHHH????-?HHHHHHHHHHHHHHHHHHHHH 2NRJ|A PF05793.7_TFIIF_alpha_seed 8 622 !Q:0,7|9,12|21,22|24,25|28,28|35,41|43,43|47,49|53,53|55,58|64,65|70,71|73,73|77,90|94,95|97,98|103,107|112,112|120,120|124,126|133,137|148,148|152,153|171,621 Q:8,8|13,20|23,23|26,27|29,34|42,42|44,46|50,52|54,54|59,63|66,69|72,72|74,76|91,93|96,96|99,102|108,111|113,119|121,123|127,132|138,147|149,151|154,170 ???---??S?--?EEEEEEEE??S??SE-EEEEEE-------E?GGG???GGG?S---?EEEEE??GGGG??E-EEE??????????????GGG??S??EEEE?????TTSS?EEEEESS-TTS--?EEEEEE?????SSEEEEEEEE?TTS?-EEEEEEEEEEEEEEGGG?????????????????????---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1ONV|A PF05806.7_Noggin_seed 6 282 !Q:0,21|26,26|28,33|35,44|49,50|54,55|66,66|68,69|77,77|79,80|82,84|100,101|103,105|111,116|120,121|123,123|126,126|142,145|152,153|166,168|171,172|177,178|196,257|262,262|281,281 Q:22,25|27,27|34,34|45,48|51,53|56,65|67,67|70,76|78,78|81,81|85,99|102,102|106,110|117,119|122,122|124,125|127,141|146,151|154,165|169,170|173,176|179,195|258,261|263,280 --------------------??SSEE?S??????S??????????TTSS??GGG??HHHHHHHHGG-G??TTTEESS?S-?S???TTHHHHHHHHHHHTS??S???HHHHT??????SSS??S?SS?HHHHHHHHHHHHHHH????EEEEEE??TTEESSEEEEEE???SS??SSSS??EEEEEEEEEEEEEEEEE-?------------------------------------------------------------SGGG?SEEEEEEEEEEEEEEEEE? 1M4U|A PF05812.7_Herpes_BLRF2_seed 15 138 !Q:0,2|25,46|48,49|83,84|96,96|107,137 Q:3,24|47,47|50,82|85,95|97,106 ???SHHHHHHHHHHHHHHHHHHHHH??????----------??????B??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??BHHHHHHHHHT?EEEEEEEGGG????------------------------??? 2H3R|A PF05822.7_UMPH-1_seed 11 269 !Q:4,4|8,8|13,15|24,24|28,28|48,48|52,52|76,76|89,91|93,93|108,109|129,129|131,133|142,142|146,146|155,155|158,160|163,163|171,171|180,192|195,196|214,214|216,223|233,233|254,255|257,257|268,268 Q:0,3|5,7|9,12|16,23|25,27|29,47|49,51|53,75|77,88|92,92|94,107|110,128|130,130|134,141|143,145|147,154|156,157|161,162|164,170|172,179|193,194|197,213|215,215|224,232|234,253|256,256|258,267 TTTB?SEE-TTEE???HHHHHHTS-TTS?HHHHHHHHHHHHHHHHHHT?SSS?HHHHHHHHHHHHHHHHHHHHHTT?BGGGHHHHHHTS???B?BTHHHHHHHHHTTT??EEEEEEEEHHHHHHHHHHH-T???TTEEEEEE?EEE?TTSBEEEE?SS???TT?HHHHHHT-THHHHHTT-------------TT??EEEEEESSSGGGGTTTT?S------??SEEEEEEEE?SSHHHHHHHHHTTSSEEEET??B?HHHHHHHHHH? 2CN1|A PF05823.7_Gp-FAR-1_seed 11 156 !Q:2,2|9,10|20,21|35,42|53,53|74,76|101,104|114,117|123,123|134,134|137,155 Q:0,1|3,8|11,19|22,34|43,52|54,73|77,100|105,113|118,122|124,133|135,136 GS?HHHHTT??HHHHHHHHH??TTTHHHHHHHHTT-???????TTHHHHHHHH?HHHHHHHHHHHHHHHHTTTT?-?HHHHHHHHHHHHHHHHHHHHHHHT????THHHHHHHH----HHHTS?HHHHHHHHHH?TT?-----------------? 2W9Y|A PF05825.6_PSP94_seed 6 94 !Q:0,0|9,9|12,12|17,17|19,19|23,23|25,26|29,29|52,53|59,59|81,81|86,88|93,93 Q:1,8|10,11|13,16|18,18|20,22|24,24|27,28|30,51|54,58|60,80|82,85|89,92 ?EEEEETTS?TT?SSSS?B?TTS?B??TT?EEEETTTEEEEEETTEEEEEES??EEESS?TTTEEEEEEGGGTEEEEEESS?TTSB???SEEE? 2IZ3|A PF05826.7_Phospholip_A2_2_seed 23 115 !Q:1,1|4,4|11,13|16,16|19,21|36,36|41,41|43,45|47,47|53,53|55,56|60,60|77,77|79,79|83,91|104,106|113,113 Q:0,0|2,3|5,10|14,15|17,18|22,35|37,40|42,42|46,46|48,52|54,54|57,59|61,76|78,78|80,82|92,103|107,112|114,114 B?TT?SSSBSS???SS-TT???SSHHHHHHHHHHHT?SSEE?T---T?EETTE-E??SSS?EEBHHHHHHHHHHHHT?S?HHH---------HHHHHHHHHHTS???EEEEES?E 1POC|A PF05830.6_NodZ_seed 6 322 !Q:0,3|9,10|12,12|32,32|38,38|41,41|44,44|57,59|69,69|76,79|90,90|96,98|118,119|121,121|127,127|129,130|135,135|146,147|149,149|175,190|210,211|214,214|223,223|239,254|285,285|295,295|302,302|308,308|314,321 Q:4,8|11,11|13,31|33,37|39,40|42,43|45,56|60,68|70,75|80,89|91,95|99,117|120,120|122,126|128,128|131,134|136,145|148,148|150,174|191,209|212,213|215,222|224,238|255,284|286,294|296,301|303,307|309,313 ????EEEEE??S?HHHHHHHHHHHHHHHHHHT?EEEEE?BT?TT?SSTTSBSHHHHB???SEETTEEEE?SGGGGT????SSEESGGGGS?GGGGS???HHHHHHHHHHHHHHHHSSS??S?SEEEE?S??TTSS?HHHHHHHHHH??B?HHHHHHHHHHHHHHTTTSEEEEEEE????????????????HHHHHHHHHHHHHHHHHHS??SS?EEEEEEES?HHHHHHHHHHSTTEE????????????????HHHHHHHHHHHHHHHHHHTTSSEEEEESTT?GGGHHHHHH?SEEEEE?TTSTT?EEEEE???????? 3SIX|A PF05833.6_FbpA_seed 114 636 !Q:0,0|14,20|24,24|36,38|46,46|48,48|55,55|60,61|65,65|71,84|97,97|105,105|120,136|139,139|141,141|147,154|159,160|164,164|173,177|185,185|187,196|203,211|213,213|216,217|219,220|222,222|224,224|230,235|237,245|248,249|261,262|271,274|279,282|284,284|287,297|313,340|342,349|352,354|358,366|371,376|379,380|382,389|392,392|404,635 Q:1,13|21,23|25,35|39,45|47,47|49,54|56,59|62,64|66,70|85,96|98,104|106,119|137,138|140,140|142,146|155,158|161,163|165,172|178,184|186,186|197,202|212,212|214,215|218,218|221,221|223,223|225,229|236,236|246,247|250,260|263,270|275,278|283,283|285,286|298,312|341,341|350,351|355,357|367,370|377,378|381,381|390,391|393,403 ?HHHHHHHHHHHGG-------GTT?EEEEEEEEETT---EEEEEEE-E-TTEEEE-EEEE??TTT?EEEEE--??-?????????HHHHHHHHHHTT?EEEEEEE-STTSSEEEEEEEEE----------------?TT-S?EEEEE--------EEEE??GGG?EEEEEETT?----BEEEESS?B??????-???BSTTSB?????????B?GG--G??H-H-HHGGG----??G---------GG??HHHHHHHHBTT??HHHHHHHH----TTSS----S?ST-----------THHHHHHHHHHHHHT----------------------------S????----EE???TTT?-----???EESS-?---?TT??S??------EE?SSHHHHHHHHT??????????--?--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1MX0|A PF05835.7_Synaphin_seed 8 155 !Q:0,56|82,154 Q:57,81 ----------------???????--?????---???------???????????????HHHHHHHHHHHHHHHHHHHHHHHHT??????-------??????????-????????----------------------------------------- 1L4A|E PF05838.7_Glyco_hydro_108_seed 20 123 !Q:7,7|10,24|26,27|30,30|34,46|61,74|76,76|80,81|87,87|104,107|122,122 Q:0,6|8,9|25,25|28,29|31,33|47,60|75,75|77,79|82,86|88,103|108,121 HHHHHHS?SS?------------??B??TT?GGG-------?-----EETTEEHHHHHHTT?------------?S?GGG??HHHHH-HHHHHHTTTTTTGGGS?---HHHHHHHHHHHHHH? 2NR7|A PF05843.9_Suf_seed 30 449 !Q:15,22|41,41|57,58|76,76|92,92|107,110|115,148|165,166|181,181|184,192|194,194|204,204|209,209|216,216|219,405|417,417|422,423|426,431|434,434|444,448 Q:0,14|23,40|42,56|59,75|77,91|93,106|111,114|149,164|167,180|182,183|193,193|195,203|205,208|210,215|217,218|406,416|418,421|424,425|432,433|435,443 HHHHHHHHHHHHHHT?-------HHHHHHHHHHHHHTGGGS?THHHHHHHHHHHTTS??HHHHHHHHHHTHHHHTT?HHHHHHHHHHHHHHT?HHHHHHHHTTTTTT--??SHHH----------------------------------HHHHHHHHHHHHHHHS-?HHHHHHHHHHHHHH?TT---------S?HHHHHHHHT?BTTB?HHHHTT?TT??????????????----------------------------------------------------------???????????----------------------------------------------------------????????????????----------------------------??TTSTTTTTTSB?TTSS--TT?----?SS?GGGTTTTTT????? 4EBA|A PF05845.7_PhnH_seed 73 287 !Q:0,20|23,26|41,42|45,55|59,59|61,64|69,70|81,82|86,86|88,94|97,97|100,100|102,103|115,117|119,119|125,125|131,131|134,135|138,141|147,158|164,164|166,166|168,176|180,207|212,220|224,229|237,251|254,255|258,259|264,264|273,273|279,279|282,282 Q:21,22|27,40|43,44|56,58|60,60|65,68|71,80|83,85|87,87|95,96|98,99|101,101|104,114|118,118|120,124|126,130|132,133|136,137|142,146|159,163|165,165|167,167|177,179|208,211|221,223|230,236|252,253|256,257|260,263|265,272|274,278|280,281|283,286 ??????----------?????HH----HHHHHHHHHHHSTT??EE?---------?SSS-S?---STTS?-HHHHHHHHHH??TTS?E-------EE?GG-G??HHHHHHHHHHH???B?SSGGG?SEEEE?TT??HH----HHHHT????????????EEEEE?S?S---------SSS?--------------------------?EEEE????--???EEE???-??HHHHHHH---------------HH??ST--TTTS?EEEEEETT-EEEEE?TT?EEEE 2FSU|A PF05848.6_CtsR_seed 48 157 !Q:0,3|23,23|28,28|39,39|63,63|67,67|77,77|81,81|91,93|95,97|115,115|127,127|132,133|135,135 Q:4,22|24,27|29,38|40,62|64,66|68,76|78,80|82,90|94,94|98,114|116,126|128,131|134,134|136,156 -?-?HHHHHHHHHHHHHTTSSSS-EEEE?HHHHHHHTTS?THHHHHHHHHHSSGGGTEEEEEE?STT?EEEEEEEEE?TTH-HHHHHHHTT?-?S???HHHHHHHHHHHHHTTSS?HHHHHHHHHHS?HHHH?-S?TTHHHHHHHHHHHHHHHHHTE 3H0D|A PF05853.7_DUF849_seed 131 371 !Q:0,0|2,2|7,7|9,9|13,13|17,17|19,19|22,23|40,40|46,46|49,52|56,60|62,62|64,65|80,85|90,93|95,95|97,113|117,117|119,121|132,140|147,147|149,149|152,155|162,166|169,169|182,182|185,187|200,200|204,204|211,211|216,216|227,227|229,229|231,234|244,245|247,247|249,252|255,259|265,267|280,281|285,285|287,295|300,300|302,302|317,317|320,320|323,323|327,327|336,337|339,339|356,357|359,360|370,370 Q:1,1|3,6|8,8|10,12|14,16|18,18|20,21|24,39|41,45|47,48|53,55|61,61|63,63|66,79|86,89|94,94|96,96|114,116|118,118|122,131|141,146|148,148|150,151|156,161|167,168|170,181|183,184|188,199|201,203|205,210|212,215|217,226|228,228|230,230|235,243|246,246|248,248|253,254|260,264|268,279|282,284|286,286|296,299|301,301|303,316|318,319|321,322|324,326|328,335|338,338|340,355|358,358|361,369 ?B?EEEE?S?SSS?GGG?T-TS??SHHHHHHHHHHHHHHT?SEEEE?EE---?TTT??---E-E??HHHHTTHHHHHHHH--??-?EEEE?---S?S?----------------TTS?H---HHHHHHHHHH------??-SEEEEE?S?EE??-?GGGGGT??-??SS-HHHHHHHHGGGG?EE???HHHHHHHHHHHH-TTT?EEEEEE?SHHH-HHHHHHHHHT-T?S-?--SSEEEEEEE--S?T----TS?-???HHHHH---HHHHHHHHHHGG--GEE-E---------EEEE?G-GGHHHHHHHHHTTT?EE-EE?TTT?SEEETTEE?-S?HHHHHHHHHHHHHHTT??B??HHHHHHHHT? 3CHV|A PF05854.6_MC1_seed 5 98 !Q:0,2|9,9|13,13|34,37|39,42|46,46|67,72|75,76|80,80|82,85|96,97 Q:3,8|10,12|14,33|38,38|43,45|47,66|73,74|77,79|81,81|86,95 ???EEEEEE?SSS?EEEEEEESSHHHHHHHHHTT----S???-SSS?EEEEEEESSSSEEEEEEEEE??????SS??SSS?S????EEEEEEEEEE?? 2KHL|A PF05856.7_ARPC4_seed 21 235 !Q:0,2|19,26|32,35|40,61|65,72|74,76|85,87|104,111|133,135|140,140|143,144|146,160|162,162|172,187|193,193|234,234 Q:3,18|27,31|36,39|62,64|73,73|77,84|88,103|112,132|136,139|141,142|145,145|161,161|163,171|188,192|194,233 ???SHHHHHHHHHHHHHHH????????SSSTT????HHHH--------?---------??--GGG--------B???EEEESSSS?--EEEEEEBSSEEEEEEE????----SHHHHHHHHHHHHHHHHTGGG---GTTB?SS??T---------------T?SEEEEEEHH----------------HHHHS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT? 2P9I|F PF05860.8_Haemagg_act_seed 57 158 !Q:0,2|5,5|10,11|16,17|27,31|43,44|46,52|55,55|61,61|64,64|67,67|75,77|82,83|85,87|95,97|100,101|105,105|110,110|114,119|121,121|128,128|131,131 Q:3,4|6,9|12,15|18,26|32,42|45,45|53,54|56,60|62,63|65,66|68,74|78,81|84,84|88,94|98,99|102,104|106,109|111,113|120,120|122,127|129,130|132,157 ???EE?SSTT??EEEE--ETTTEEEEE?????TTSEEEEEEEE??B?------TT?EEEEE?SS?EE-ETTTEEE???TTSS--S???SEEEEEE--?SS??EEE?SEEE-EEE------S?EEEEEE?TT?EEESSEEEESEEEEEEESSEEEEETT 2ODL|A PF05865.6_Cypo_polyhedrin_seed 2 248 !Q:0,3|10,10|42,42|46,46|63,63|69,71|75,77|93,93|95,96|98,98|101,101|105,105|113,113|127,127|131,131|139,140|142,142|144,145|149,149|167,168|172,174|183,185|188,189|206,206|215,215|229,230|233,233|236,237|240,243|246,247 Q:4,9|11,41|43,45|47,62|64,68|72,74|78,92|94,94|97,97|99,100|102,104|106,112|114,126|128,130|132,138|141,141|143,143|146,148|150,166|169,171|175,182|186,187|190,205|207,214|216,228|231,232|234,235|238,239|244,245 ????TTSSTT?HHHHHHHHHHHHHHHHHHSTTSEEEEEEEEE?TTS?EEEEEEEEESEEEEEE?HHHHS???TTS???HHHHHHHHHHHHSTT?S??S?SS?TTS?SEEEEEE?TTEEEEEEEEEEE?TTS?TTSSGGG??S?B??GGG?EEEEETTEEEEEEEEEE??STT???EEEEEEEE???SS??TTSTTTHHHHHHHHHH?EEEEEEES?HHHHHHHTTGGGT??EE?TT??EE????TT?? 2OH5|A PF05866.6_RusA_seed 96 220 !Q:1,17|23,28|31,31|33,39|45,46|54,55|67,73|75,75|77,88|91,91|98,98|103,137|142,144|154,163|166,180|185,185|189,190|200,202|205,210|219,219 Q:0,0|18,22|29,30|32,32|40,44|47,53|56,66|74,74|76,76|89,90|92,97|99,102|138,141|145,153|164,165|181,184|186,188|191,199|203,204|211,218 E?-?---------??--?HHHHE------EE?S-------SSEEE?-HHHHHHH--HHHHHHHHHTT????---B?S-----------?EE-EEEEEE?SSSS?-----?---------------------------?GGGS---SHHHHHHHH----------HT---------------TSBS?GGG--EEEEEEEEE???TT-----?EEEEEEEE? 2H8E|A PF05870.6_PA_decarbox_seed 8 161 !Q:0,0|12,12|15,16|33,33|40,40|47,47|63,63|67,67|87,87|93,93|98,98|116,118|120,120|135,136|139,139|144,144|146,148|160,160 Q:1,11|13,14|17,32|34,39|41,46|48,62|64,66|68,86|88,92|94,97|99,115|119,119|121,134|137,138|140,143|145,145|149,159 ?TTTTTEEEEEE?TT??EEEEEEEETTEEEEEE?SSTTTT?EEEEEE?EEEEEETTEEEEEEE?TTS?EEEEEEEGGGTEEEEEEEE?HHHHH?GGGG?SBGGGGHHHHHHHHHHS???S?EEEEEEEEEEEEEE??SS?TTSS?S???TTHHHHHHHHT? 2W2B|A PF05871.7_ESCRT-II_seed 25 219 !Q:4,4|10,11|13,13|37,38|41,41|44,76|81,81|83,84|87,98|113,116|118,120|125,126|129,140|143,158|164,164|170,170|173,173|189,189|196,196|205,206|208,208|210,210|215,216 Q:0,3|5,9|12,12|14,36|39,40|42,43|77,80|82,82|85,86|99,112|117,117|121,124|127,128|141,142|159,163|165,169|171,172|174,188|190,195|197,204|207,207|209,209|211,214|217,218 GGGG?GGGGS??S?HHHHHHHHHHHHHHHHHHHTTTT??EE?SS????????????????????-------????-?TTTS?T--TT?--------???HHHHHHHHHHHHTT----T---SEEE?-SS------------SS??--------------SSSTT?SSEEE?SS?HHHHHHHHHHHHHHH?TTSSEE?HHHHTTTT??S-S?TTTT??HH 1U5T|C PF05873.7_Mt_ATP-synt_D_seed 5 180 !Q:0,10|19,19|44,44|47,51|59,59|61,62|77,95|133,179 Q:11,18|20,43|45,46|52,58|60,60|63,76|96,132 ???????????HHHHHTTS?GGGHHHHHHHHHHHHHHHHHHHHS?SS?????HHHHHHT?S--STTHHHHHHHHHTT??????-------?--???TTHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHT???????????????????????-????????--------??????? 2WSS|U PF05881.7_CNPase_seed 5 248 !Q:0,1|9,9|41,51|57,57|59,61|63,64|71,71|85,85|94,94|106,106|116,117|124,125|128,128|130,137|142,145|150,150|157,157|160,161|180,182|191,193|222,247 Q:2,8|10,40|52,56|58,58|62,62|65,70|72,84|86,93|95,105|107,115|118,123|126,127|129,129|138,141|146,149|151,156|158,159|162,179|183,190|194,221 ??SEEEEEE?HHHHHHHHHHHHHHHHHHHHSHHHHHTHHHH???????????HHHHS?B???S??EEEEEE?GGGTSTTHHHHHH?HHHHHHTT?EEEEEEEEEEE?SSEEEEEEE??TTGGGG??SS?S?-------SSTT????TTTT?EEEEEE?TT??TTHHHHHHHHHHHHHHTT???EEEEEETT---EEEEEEETTEEEEEEEEEEEEEEEEEEE??------------------------ 2YDB|A PF05889.8_SLA_LP_auto_ag_seed 5 424 !Q:5,5|8,13|16,20|22,22|32,33|35,35|38,38|41,41|44,47|73,73|76,77|85,85|101,101|104,105|111,114|116,118|129,129|135,135|146,146|155,155|159,159|170,170|172,173|177,180|193,194|199,199|202,202|205,205|220,222|233,235|238,238|245,245|257,257|259,259|261,261|307,322|324,326|329,329|337,337|341,341|346,349|363,364|366,366|368,368|371,371|374,375|392,393|396,396|402,403|406,407 Q:0,4|6,7|14,15|21,21|23,31|34,34|36,37|39,40|42,43|48,72|74,75|78,84|86,100|102,103|106,110|115,115|119,128|130,134|136,145|147,154|156,158|160,169|171,171|174,176|181,192|195,198|200,201|203,204|206,219|223,232|236,237|239,244|246,256|258,258|260,260|262,306|323,323|327,328|330,336|338,340|342,345|350,362|365,365|367,367|369,370|372,373|376,391|394,395|397,401|404,405|408,423 TBGGG?SS--????SS?????S?HHHHHHTTT??S?BS?SS?TT???-TTBHHHHHHHHHHHHHHHHHHHHTT?TT??EEEEESS?HHHHHHHHHHHHHHH?TT??EEEEE????H---HHHHHHHHTT?EEEEE?EEEETTEEEE?HHHHHHHH-HHH?GGGEEEEEEE?S??TTB????HHHHHHHHHHHT??EEEE?TT?TT?HHHHHHHHHHHHHS???EEEEEHHHHH???SS?EEEEES?HHHHHHHHHTS?S?B?SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT--------------??B???TT?SSEEEEE?TTS?TTTS---?HHHHHHHHHHHTT??S?E-EE?TT??EEETTEEESSTTTTSS??SS?EEEEE??TT??HHHHHHHHHHHHHHHH 1MDX|A PF05891.7_Methyltransf_PK_seed 7 252 !Q:0,0|16,16|26,29|31,33|52,64|72,72|86,97|106,106|120,125|136,137|141,148|151,151|160,160|165,165|198,198|223,224|231,232|234,235|237,240|243,243|251,251 Q:1,15|17,25|30,30|34,51|65,71|73,85|98,105|107,119|126,135|138,140|149,150|152,159|161,164|166,197|199,222|225,230|233,233|236,236|241,242|244,250 ?HHHHHHHHHHHHHTS?SSHHHHTTT?---G---GGHHHHHHHHHHHHHGGG??-??---?????SEEEEET?TTTHHHHHTTTTT?-----------SEEEEEES?HHHHHHHHHHTGG------GGGGEEEEEE??GGG????----SS?EEEEEEES?GGGS?HHHHHHHHHHHHHHEEEEEEEEEEEEEBSSSE-EEETTTTEEEEBHHHHHHHHHHTT??EEEEEE??S??T----TS?EEEEEEE? 3UJC|A PF05893.9_LuxC_seed 13 445 !Q:4,4|23,29|39,41|52,54|68,70|73,77|84,85|100,100|107,108|127,127|133,134|138,138|153,154|156,167|173,177|181,183|190,190|193,194|201,201|211,212|215,215|222,222|225,228|232,232|236,241|259,259|263,263|271,273|290,290|292,294|296,296|299,299|302,307|309,309|315,318|326,327|331,332|336,336|341,343|347,354|359,360|362,364|368,370|383,385|388,391|395,395|408,408|413,415|426,434 Q:0,3|5,22|30,38|42,51|55,67|71,72|78,83|86,99|101,106|109,126|128,132|135,137|139,152|155,155|168,172|178,180|184,189|191,192|195,200|202,210|213,214|216,221|223,224|229,231|233,235|242,258|260,262|264,270|274,289|291,291|295,295|297,298|300,301|308,308|310,314|319,325|328,330|333,335|337,340|344,346|355,358|361,361|365,367|371,382|386,387|392,394|396,407|409,412|416,425|435,444 HHTS?HHHHHHHHHHHHHHHHHH-------HHHHHHHHH???HHHHHHHHHH---HHHHHHTTTGGGG???EE-----EESTTS--STTTTEEEEEEEEE?SEEEEE??SSSTTHHHHHHHHHHHTT?EEEEE??TTS?HHHHHHHHHHHHTT??T------------TSEEE???-?GGG---THHHHT?TT??EEEEES?HHHHHHHHH--HH?SSEEEE?EE----EEE?TTS-----?HHHHHHHHHHHHHGGGG?STT?EEEEEEE---HHHHHHHHHHHHHHHH-T???S?TT?TT??????S?HHHHH----HHHHHHH--HHH--HTT?EEEE???EEE--------TTEE??E---EEE-??HHHHTTSHHHHS???SS----EEE-EEEESSHHHHHH-HHHT---SSEESEEEEE???------HHHHHHHHHH 1UXN|A PF05899.7_Cupin_3_seed 33 111 !Q:9,9|14,14|22,22|25,26|30,33|44,54|57,60|62,63|65,70|77,77|82,82|85,91|101,101|104,107 Q:0,8|10,13|15,21|23,24|27,29|34,43|55,56|61,61|64,64|71,76|78,81|83,84|92,100|102,103|108,110 HHHHTGGGS?EEEE?SEEEEEE?SS-?EEE----EEEEEEEEEE-----------ET----T??E------EEEETT?EEEE?TT?------EEEEEEEEE-EE----EEE 3BCW|A PF05903.9_Peptidase_C97_seed 41 232 !Q:11,13|21,33|41,55|62,68|73,73|77,78|80,89|91,91|94,111|117,121|125,126|128,128|133,137|143,145|154,156|162,163|165,168|170,171|175,175|181,181|196,204|224,226|230,231 Q:0,10|14,20|34,40|56,61|69,72|74,76|79,79|90,90|92,93|112,116|122,124|127,127|129,132|138,142|146,153|157,161|164,164|169,169|172,174|176,180|182,195|205,223|227,229 EEEEEEEEETT---TTHHHHH-------------HHHHHSS?--------????--EEEEEE-------ETTE-EEE??T----------T?SE------------------EESTT?----STT?-S?SEEE-----EEEEE???HHHHHHHH---HHHHT--T----T??GGG?BTTTB?HHHHHHHHHHHHHS???-----?HHHHTHHHHHHTSHHHHHH---TTT?? 2WP7|A PF05907.8_DUF866_seed 9 172 !Q:0,2|19,25|28,29|39,39|42,42|50,50|53,53|57,57|62,62|65,65|70,71|76,77|84,85|96,97|100,100|117,119|121,121|128,128|131,131|137,138|142,143|165,171 Q:3,18|26,27|30,38|40,41|43,49|51,52|54,56|58,61|63,64|66,69|72,75|78,83|86,95|98,99|101,116|120,120|122,127|129,130|132,136|139,141|144,164 ???EEEEEEEEEESEEEEE??-----TT??EEEEEEETT-SS?EEEEEEE?TT?BEE?TTSS?EE-SEEE??SSSS??EEEEEE??TTTEEEGGGT--TS?EEEEEEEEESEEEEEE???S?EEEEET-TS?EEEEE??TTS-?EEEEETTTTEEEEEEEEEEEE?------ 1ZSO|A PF05908.6_DUF867_seed 37 221 !Q:11,11|23,26|52,54|58,59|67,68|71,72|77,79|83,88|98,98|108,109|112,120|127,127|143,149|152,153|156,159|162,162|170,175|178,179|197,199|205,205|207,210 Q:0,10|12,22|27,51|55,57|60,66|69,70|73,76|80,82|89,97|99,107|110,111|121,126|128,142|150,151|154,155|160,161|163,169|176,177|180,196|200,204|206,206|211,220 SSSHHHHHHHS?BTTTEEEEEEE?-?-SSEEEEEEEEETTSTTHHHHHHHHH---HHH??EEEEEEE??SS?-GGGG???GGG??---?HHHHHHHHT?SEEEEEEEE??SS-----?-??EEEESS?HHHHHHHHHHHHHTT???----EE??SS????SS?SGGGGST------TS??EEEEEEHHHHHHTBGGG???GGGTT?B---?HHHHHHHHHH 3A9L|A PF05913.6_DUF871_seed 48 392 !Q:6,6|11,12|36,50|65,65|72,72|75,85|92,92|95,95|103,104|115,115|118,119|128,139|151,152|160,162|164,164|168,168|171,171|187,192|197,198|200,200|202,203|205,205|209,210|212,216|226,226|240,241|246,246|249,251|262,263|274,274|277,278|289,289|292,293|296,296|304,304|309,313|317,317|320,330|332,332|340,340|349,349|354,354|356,356|358,360|370,370|380,381|384,384|390,391 Q:0,5|7,10|13,35|51,64|66,71|73,74|86,91|93,94|96,102|105,114|116,117|120,127|140,150|153,159|163,163|165,167|169,170|172,186|193,196|199,199|201,201|204,204|206,208|211,211|217,225|227,239|242,245|247,248|252,261|264,273|275,276|279,288|290,291|294,295|297,303|305,308|314,316|318,319|331,331|333,339|341,348|350,353|355,355|357,357|361,369|371,379|382,383|385,389 EEEEEE?GGGS-?HHHHHHHHHHHHTTTEEEEEEEE????---???-????HHHHHHHHHHHHTT?EEEEEE?TT???????????THHHHH-HT?SEEEESS??SSHHHHHHTT?TT??EEEEETTS-----------?SSHHHHHTTSS??GGGEEEE???B?STT?SB?HHHHHHHHHHHHHTT--?-??EEEE??S-S??B?SSS??S---??BSBGGGTTS?HHHHHHHHHHTTS??EEEE?SB???HHHHHHHHHS-?SSSEEEEEEE?TT??HHHHHHHHSS?EE??SS?BTTEEEE?THHH-----HHT-TS?????--????B?TTEEEEE?GGGGGGTT?EEEE?S?B???TTEEEEEEE?GGGGGGGGG??TT?EEEEE-? 1X7F|A PF05916.6_Sld5_seed 176 312 !Q:10,10|14,33|36,36|40,41|43,44|47,48|60,90|96,161|163,164|179,191|200,200|205,229|234,235|238,241|256,291|295,307 Q:0,9|11,13|34,35|37,39|42,42|45,46|49,59|91,95|162,162|165,178|192,199|201,204|230,233|236,237|242,255|292,294|308,311 EEEEHHHHHH-HHH--------------------TT?EEE--E??TT??HHHHTTHHHHH-------------------------------TTSSS----???----------------------------------------------------------?S--STTHHHHHHHHHHH------------?GGGSSSHH-HHHH-------------------------HHHH--HH----HHHHHHHHHHHHHH------------------------------------HHT???????--????TTTT 3ANW|B PF05918.6_API5_seed 3 604 !Q:0,0|35,35|53,53|70,70|87,90|93,93|107,109|127,127|141,143|146,146|165,165|170,172|190,191|208,210|233,238|241,241|259,259|264,265|279,280|284,293|309,312|331,348|366,366|372,393|421,431|434,435|464,479|483,603 Q:1,34|36,52|54,69|71,86|91,92|94,106|110,126|128,140|144,145|147,164|166,169|173,189|192,207|211,232|239,240|242,258|260,263|266,278|281,283|294,308|313,330|349,365|367,371|394,420|432,433|436,463|480,482 ?HHHHHHHHHHHHHTGGGGGGGHHHHHHHHHGGGS?HHHHHHHHHHHHHHGGG?GGGHHHHHHHHHHHHT?SSHHHHHHHHHHGGGG--??TT?HHHHHHHHHHHTT???HHHHHHHHHHHHHHHHH?HHHHHHHHHHHHH---HS?HHHHHHHHHHHHHHGGGS?TTTS?--HHHHHHHHHHHHHHTTS??HHHHHHHHHHHHTSGG---GSSHHHHHHHHHHHHHHHTTTS?---??SS?HHHHHHHHHHHHHHGGG?BTTB??HHHHHHHHHHTGG--GTT??????????HHHHHHHHHHHHHTT????TTHHHHHHHHHHHHHTTS??????????????????HHHHHHHHHHHHHHHTT?THHHH??----------------????TTHHHHHHHHHHHHHHHHHHHHHHHHH-----------TT??TTGGGSHHHHHHHHHHHHHHHHHHHHHH???????????--???TTS????------------------------------------?????????---???????-????????????????????????????----????????-------------??------ 3U0R|A PF05920.6_Homeobox_KN_seed 99 94 !Q:8,13|15,17|19,23|26,35|37,38|41,46|51,52|54,55|58,67|69,77|81,85 Q:0,7|14,14|18,18|24,25|36,36|39,40|47,50|53,53|56,57|68,68|78,80|86,93 HHHHTTTS--????H---H-----HH----------H--HH------HHHH--T??HH----------H---------HHH-----HHHHHHHH 2LY9|A PF05922.11_Inhibitor_I9_seed 160 171 !Q:6,6|9,49|52,60|70,77|80,116|118,118|124,124|127,134|142,143|148,148|153,153|155,155|164,165|170,170 Q:0,5|7,8|50,51|61,69|78,79|117,117|119,123|125,126|135,141|144,147|149,152|154,154|156,163|166,169 EEEEEE?TT-----------------------------------------TT???------HHHHHHHHH--------HT-------------------------------------T?EEEEE?SS--------SSEEEEE??HHHH-HHHH-H?TTEEEEEE??EEEE? 3GCW|P PF05923.7_APC_crr_seed 30 30 !Q:0,29 Q: ????????-???????-?????--?????? 1V18|B PF05924.6_SAMP_seed 11 21 !Q:0,1|3,3|15,20 Q:2,2|4,14 ??H-HHHHHHHHHTS??---- 1EMU|B PF05925.7_IpgD_seed 2 569 !Q:0,49|54,55|58,59|63,64|66,71|95,95|99,99|116,118|120,121|139,141|151,153|176,568 Q:50,53|56,57|60,62|65,65|72,94|96,98|100,115|119,119|122,138|142,150|154,175 -------------------------------???????????????????EEEE??SS??GGG--G??????SSSBHHHHHHHHHHHHHHHHHHT-TTS?HHHHHHHHHHHHGGGS???B??HHHHHHHHHHHHHHHHH---HHHHHHHHS???HHHHHHHHHHHHHHHHHHHHTT?????????????-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 4DID|B PF05927.6_Penaeidin_seed 8 87 !Q:0,22|24,24|30,50|52,55|58,59|62,63|66,66|79,79|81,81|83,85 Q:23,23|25,29|51,51|56,57|60,61|64,65|67,78|80,80|82,82|86,86 -------------------????S?SSSSS???------?????????-??S???-SS??TT??SS?HHHHHHHHHHHS?S?S???S 1XV3|A PF05930.7_Phage_AlpA_seed 23 58 !Q:4,4|15,15|25,30|33,33|35,37|44,44|46,46 Q:0,3|5,14|16,24|31,32|34,34|38,43|45,45|47,57 SSEE?HHHHHHHHSS?HHHHHHHHH------HH-H???SEESSS?E-EEEHHHHHHHH 1Z4H|A PF05932.8_CesT_seed 52 132 !Q:11,13|15,19|29,29|58,59|62,66|76,76|79,79|85,85|107,111|114,114 Q:0,10|14,14|20,28|30,57|60,61|67,75|77,78|80,84|86,106|112,113|115,131 HHHHHHHHHHT?--S?????TTSEEEEEE-TTTEEEEEEEETTTTEEEEEEEEEEGGG??TT-----HHHHHHHHH-HT-GGGTT?EEEEETTTTEEEEEEEEETTT---??HH-HHHHHHHHHHHHHHHHH 1S28|A PF05935.6_Arylsulfotrans_seed 33 715 !Q:0,0|7,9|12,12|20,20|23,25|33,34|36,36|40,42|48,52|62,70|75,77|91,92|97,99|108,117|120,120|125,128|135,135|137,137|140,140|143,143|152,153|156,160|163,166|170,170|173,176|183,184|193,193|197,197|203,203|208,209|213,214|218,218|221,221|227,227|231,231|238,248|251,251|256,256|259,262|267,267|270,271|275,286|288,288|290,290|292,292|296,296|299,305|307,307|319,319|322,324|326,333|336,338|340,340|346,347|351,351|363,365|368,369|375,375|377,389|393,396|398,403|405,406|412,412|415,415|419,419|421,422|443,443|450,454|458,458|465,465|468,469|471,472|475,481|483,483|488,488|492,492|496,496|498,499|501,501|505,511|517,520|523,523|529,529|532,532|534,541|547,548|555,556|561,572|574,578|603,603|608,609|612,613|616,617|637,648|657,676|686,690|701,701|703,706|709,713 Q:1,6|10,11|13,19|21,22|26,32|35,35|37,39|43,47|53,61|71,74|78,90|93,96|100,107|118,119|121,124|129,134|136,136|138,139|141,142|144,151|154,155|161,162|167,169|171,172|177,182|185,192|194,196|198,202|204,207|210,212|215,217|219,220|222,226|228,230|232,237|249,250|252,255|257,258|263,266|268,269|272,274|287,287|289,289|291,291|293,295|297,298|306,306|308,318|320,321|325,325|334,335|339,339|341,345|348,350|352,362|366,367|370,374|376,376|390,392|397,397|404,404|407,411|413,414|416,418|420,420|423,442|444,449|455,457|459,464|466,467|470,470|473,474|482,482|484,487|489,491|493,495|497,497|500,500|502,504|512,516|521,522|524,528|530,531|533,533|542,546|549,554|557,560|573,573|579,602|604,607|610,611|614,615|618,636|649,656|677,685|691,700|702,702|707,708|714,714 ?EEESTT---SS?TTEEEEE?TT???EEEEEEE??S-STT???EEEEE?----HHHHHHHTE---------EEEE???TTSEEEEEEEEEE--TTEE---EEEEEEEE??????????TT?SSSS?---EEEEEE-E?TT?TT?EEEEEEEE??SS?????EE????TTS?TT????EETTTT??BEEEEEEE?TTS?EEEEE?GGGT??SSS??GGG?SB?EEEEE?TTS?EEEEEB-----------TE-EEEE?TT??--EEEE-EE??TTE------------E?B?S?EEE?TT-------S?EEEEEEESSEE?TT---S-------?EE???S?EEEEE?-TTS?EEEEEEGGGTS--?TT??TTTTT?B?????????????SSB????T------T??SSSSS?SS-TTS?S??EEEEEEETTTTEEEEEETTT-EEEEEE-----TTS?EEEEES?ST--T??TT-------T-GGGB?EEB?TTS?B??B?TTS?------BSSSS????SS?EEEEE?TT-S-------?EEEEE??TTGGGS??SSGG------------G?--??EEEEEEEETTTTEEEEEEEESGGG-GGGG??SS??EE--EEETTTTEEEEEEEEETTT------------STTSEEEE--------------------EEEEEETTT---??EEEEEEEEEE-E----ET??-??E 3ETS|A PF05942.6_PaREP1_seed 116 138 !Q:0,0|3,3|20,20|45,45|58,59|63,79|87,87|91,91|93,94|106,106|112,114|117,122 Q:1,2|4,19|21,44|46,57|60,62|80,86|88,90|92,92|95,105|107,111|115,116|123,137 ?SS?HHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHHHHHHHHHHT?HHHHHHHTTSSS??HHH-----------------HHHHHHS?TTT?T--THHHHHHHHHH-HHHTT--?SS??--??HHHHHHHHHHHHHHH 2JPU|A PF05946.7_TcpA_seed 14 136 !Q:9,9|15,15|22,22|34,37|49,49|64,64|74,76|81,82|86,88|92,92|100,100|102,102|105,105|107,109|112,112|121,125|129,129 Q:0,8|10,14|16,21|23,33|38,48|50,63|65,73|77,80|83,85|89,91|93,99|101,101|103,104|106,106|110,111|113,120|126,128|130,135 HHHHHTTSS?HHHHB?TTTSSB?EEEEEEETTEE----EEEEEEEEEEE?HHHHHHHHHHHGGG?SEEEEEESS???HHHH??TTT???BGG-GSSEEEE?S?TT?B???TT?HHHHHHTT?----SSS?EEEEEE 3VOR|A PF05949.7_DUF881_seed 103 201 !Q:0,1|14,14|26,26|29,51|55,55|68,68|75,80|83,83|87,88|91,92|97,98|101,102|109,109|113,113|115,118|120,121|129,133|138,138|156,161|163,163|172,177|182,194|197,197|200,200 Q:2,13|15,25|27,28|52,54|56,67|69,74|81,82|84,86|89,90|93,96|99,100|103,108|110,112|114,114|119,119|122,128|134,137|139,155|162,162|164,171|178,181|195,196|198,199 ??HHHHHHHHTTSS?EEEEEEEEEEE?SS??-------------------??HHH-HHHHHHHHHHTT?SEEEEE?-----SS?EEE??TT??EEEE--TT--EEEETT-EEE?S----S--EEEEEES?----HHHH-HHHHTSTTSHHHHHHHT------T?EEEEEEEE------EEEE-??????---???SS?EE? 3GMG|A PF05954.6_Phage_GPD_seed 283 627 !Q:2,2|6,6|8,9|16,18|20,33|35,38|40,40|43,44|48,50|54,54|61,94|97,100|106,122|126,131|134,146|150,153|156,158|161,164|166,168|174,174|180,187|190,194|198,204|206,208|211,211|213,213|225,225|228,230|232,233|238,238|241,241|244,256|259,267|272,272|274,276|290,290|294,295|299,299|306,316|318,319|328,328|331,335|339,348|353,371|377,377|381,529|531,533|541,542|555,556|559,560|563,574|582,583|587,597|603,610|625,626 Q:0,1|3,5|7,7|10,15|19,19|34,34|39,39|41,42|45,47|51,53|55,60|95,96|101,105|123,125|132,133|147,149|154,155|159,160|165,165|169,173|175,179|188,189|195,197|205,205|209,210|212,212|214,224|226,227|231,231|234,237|239,240|242,243|257,258|268,271|273,273|277,289|291,293|296,298|300,305|317,317|320,327|329,330|336,338|349,352|372,376|378,380|530,530|534,540|543,554|557,558|561,562|575,581|584,586|598,602|611,624 EE-ETT-S??EEEEEE---E--------------E----S?TT??GGG---TTT?EEEEEE?--------------------?????????????EE----EEEEE-----------------EEE------EE-------------EEE---?SS--?EE----E---EEEEE?GGGGG--------GG?-?-?BEE-------E---EE-E?HHHHHHHHHHT-TT???S--SSEE-EE?SS---?------???EE---------EEEE?S-??HHHHHHHHHHHHT?EEE--EEE-ETTTTE-----------E--EEEEESSG-GG-----SEE----------EEEE????????????----???EEEEE-EEE??????????????---??????-----------------?????--------------------??????---------?---------???????--?????--------------???????????-----------------???S---SHHHHHH--HHHHHTTEEEEE--EE??SS---------?-?TTEEEEE??SSS----------?HHHHH-------?EEEEEEEEEEETTT?? 1WRU|A PF05958.6_tRNA_U5-meth_tr_seed 9 366 !Q:20,24|28,30|34,34|46,47|57,57|61,66|70,70|72,73|77,77|94,94|109,109|112,112|123,125|144,144|161,161|168,169|174,175|184,186|206,207|209,209|216,216|236,238|254,255|261,263|274,277|282,283|286,286|290,291|298,300|303,305|324,324|348,349|355,356|365,365 Q:0,19|25,27|31,33|35,45|48,56|58,60|67,69|71,71|74,76|78,93|95,108|110,111|113,122|126,143|145,160|162,167|170,173|176,183|187,205|208,208|210,215|217,235|239,253|256,260|264,273|278,281|284,285|287,289|292,297|301,302|306,323|325,347|350,354|357,364 GHHHHHHHHHHHHHHHHTTT?????EEE???SSS?BSEEEEEEEEE--TTEEEEEEE?TTT?----?EEE?S??TTB?HHHHHHHHHHHHHHTT?HHHHTTEEEEEEEE?TT?EEEEEEEESS???HHHHHHHHHHHHHHHTTT?EEEEEEEETTEEEESS?SEEEEE??BTTB??EEEEETTS???SBHHHHHHHHHHHHHHTTT??S-EEEEES?TTSHHHHHHGGGSSEEEEE???HHHHHHHHHHHHHTT??SEEEE???SHHHHHHHSS????TTGG--GS?GGG??EEEEEE???TT???HHHHHHHTTSSEEEEEES?HHHHHHHHHHHHHHEEEEEEEEE??STTSS??EEEEEEEE? 2BH2|A PF05960.6_DUF885_seed 150 1264 !Q:0,0|5,5|10,11|18,24|27,39|57,82|84,84|87,97|110,110|117,118|121,123|127,131|140,140|143,143|146,156|170,170|172,183|188,233|251,251|260,261|266,268|270,272|284,324|330,345|347,347|350,356|371,380|384,384|411,414|420,421|428,438|441,442|449,474|484,486|492,496|498,498|521,521|526,530|532,535|537,544|546,567|579,581|585,587|589,613|619,620|634,645|648,648|653,653|656,665|667,670|675,676|678,684|691,691|693,693|698,704|709,711|713,714|719,721|723,733|738,738|744,747|768,769|772,772|774,774|780,790|792,792|805,805|808,808|812,812|818,823|825,878|882,898|904,904|921,922|925,942|946,1055|1065,1068|1070,1167|1175,1177|1183,1183|1185,1186|1204,1204|1210,1212|1216,1218|1222,1233|1245,1245|1247,1248|1257,1259 Q:1,4|6,9|12,17|25,26|40,56|83,83|85,86|98,109|111,116|119,120|124,126|132,139|141,142|144,145|157,169|171,171|184,187|234,250|252,259|262,265|269,269|273,283|325,329|346,346|348,349|357,370|381,383|385,410|415,419|422,427|439,440|443,448|475,483|487,491|497,497|499,520|522,525|531,531|536,536|545,545|568,578|582,584|588,588|614,618|621,633|646,647|649,652|654,655|666,666|671,674|677,677|685,690|692,692|694,697|705,708|712,712|715,718|722,722|734,737|739,743|748,767|770,771|773,773|775,779|791,791|793,804|806,807|809,811|813,817|824,824|879,881|899,903|905,920|923,924|943,945|1056,1064|1069,1069|1168,1174|1178,1182|1184,1184|1187,1203|1205,1209|1213,1215|1219,1221|1234,1244|1246,1246|1249,1256|1260,1263 ?HHHH-HHHT??HHHHSS?-----?TT???----?--?-?HHHHHHHHHHHHHHHHH--------------------------H-HH????----???HHHHHHHHHHHH-HHHHHH??TT???SEE-----ETTTEEES?SS?SS?----------SHHHHHHHHHHHT-S???---------SHHH----------------------------------------------HHHHHHHHHTHHHHHHH-HHHHHHHH--HHTT???B---HHHHHHHHHHH-----------------------------------------HHHTS----------------S?GG-------GSHHHHHHHHHHTT?---------TTS?HHHHHHHHHHHHHHHHHTHHHHHHHH----HHHHH--HHTTTS-----------BS??SGGGST--------------------------THHHHHHHH---HHHHH?-?-?S?HHHHHHHHHHHHHHHHHHHHHH-HHHT-----T?--?S--------S---------------------?HHHHHHHHHTS---GGG???S-------------------------SHHHH--HHHHHHHHHHHHH------------HH-HHTG-GG?---?--???S-???EEEE??H-------HHHTTS?S-EEEE?-??---TTSS---S??EEEE??-S?----------GGGS?GGGHH----HHHHHHSTTTHHHHHHHHHT?-TT-S?HHHHT--?-----??-H-HHHHHHHHHHHH-HH-HHT-TTTTT-----?H------------------------------------------------------HHH-----------------HHHHH-HHHHHHHHHHHHHHHH--TS---------------???HHH--------------------------------------------------------------------------------------------------------------HHHHHHHHH-???H--------------------------------------------------------------------------------------------------HHHHHHH---HHHHH-S--TTGGGHHHHHHHHHHHH-HHHHH---HHH---GGG---??-------HHHHHHHHHTT?S??HHHHHHHH---HHHH 3O0Y|A PF05962.6_HutD_seed 106 326 !Q:1,1|5,6|9,15|23,34|37,37|39,43|48,48|50,52|61,61|63,63|66,67|69,71|74,74|85,85|92,102|106,123|125,125|128,130|138,138|147,148|157,157|169,170|175,188|193,198|201,202|207,212|219,224|227,233|239,247|254,254|257,257|260,275|280,298|300,300|306,307|313,316|319,319 Q:0,0|2,4|7,8|16,22|35,36|38,38|44,47|49,49|53,60|62,62|64,65|68,68|72,73|75,84|86,91|103,105|124,124|126,127|131,137|139,146|149,156|158,168|171,174|189,192|199,200|203,206|213,218|225,226|234,238|248,253|255,256|258,259|276,279|299,299|301,305|308,312|317,318|320,325 E?GGG??EE???????EEEEEEE------------SS?S-----GGGS?S---EEEEEEEE?S?EE--E???TT?EEEEEEEESS?EEEEET-----------TEE?----??-----------B?BT?-?EEEETTS?EEEEESSS?-EEEEEEEE?TTTEEEEEEEE--EEEE--------------EEEE------EE??SEEE------EEESSS-?----EE-------EEETT---------EEEEEE?TT?EE----------------EEES??-----------------S?EEEEE--EEEEE----EE-EEEEEE 3ESG|A PF05963.6_Cytomega_US3_seed 3 203 !Q:0,42|53,53|66,67|69,69|81,81|83,86|89,92|99,99|114,115|118,119|129,129|132,132|139,202 Q:43,52|54,65|68,68|70,80|82,82|87,88|93,98|100,113|116,117|120,128|130,131|133,138 -----------------------------------------??EEEEEEEEEE?SSEEEEEEEEEE??S?EEEEEEEESSS?E----EE????GGGEEE-ETTTEEEEEEEEEE??TT??EEEEEEEET-TE-EEEEEE????------------------------------------------------------------ 1IM3|D PF05964.9_FYRN_seed 45 59 !Q:11,13|16,16|21,21|24,24|26,27|38,42|45,45 Q:0,10|14,15|17,20|22,23|25,25|28,37|43,44|46,58 ETTEEEEEEEE???SS-GGGB?SS?B??EEEEEEEEEE?----SS?TTSEEEEEEEEEE 2WZO|A PF05965.9_FYRC_seed 48 104 !Q:9,9|13,17|20,22|24,24|44,45|49,60|63,66|91,91|94,103 Q:0,8|10,12|18,19|23,23|25,43|46,48|61,62|67,90|92,93 SSSEEEEEE-ETT----?GG---G?EEESSHHHHHHHHHHHHHH--HHT???---------TT????HHHHHTTTSHHHHHHHTTSTTGGG?TT??????---? 2WZO|A PF05966.7_Chordopox_A33R_seed 6 213 !Q:0,108|126,127|140,140|142,144|152,160|171,171|178,186|189,198|201,202|211,212 Q:109,125|128,139|141,141|145,151|161,170|172,177|187,188|199,200|203,210 --------------------------------------------------------------------------------------------------???????????SSEEETTEEEEEEEEEE?-HHHHHHHHHHTT?B???HHHHTTS---------TTHHHHBTSB?TTSSBB--------?SS??-???????TT??EEEEEEEE?? 3K7B|A PF05969.6_PSII_Ycf12_seed 40 36 !Q:0,8|32,35 Q:9,31 ?--??????THHHHHHHHHHHHHHHHHHHHTT??-? 3PRR|y PF05971.7_Methyltransf_10_seed 4 313 !Q:0,42|44,44|64,71|75,78|94,97|100,100|102,107|114,114|129,130|138,138|153,153|155,155|164,165|168,168|177,178|180,181|188,235|265,265|288,288|311,312 Q:43,43|45,63|72,74|79,93|98,99|101,101|108,113|115,128|131,137|139,152|154,154|156,163|166,167|169,176|179,179|182,187|236,264|266,287|289,310 --------------------------------------?????S?TTSHHHHHHHHHHHHHHHH????-???TTS????HHHHHHHHHHHHHHH????GG-G??--??EEEEES?TTTTHHHHHHHHHH??EEEEEES?HHHHHHHHHHHHHT-T?TTTEEEEE??TT?SSTTTSTT??S??BSEEEE???????????????????---???--------------?????????TTTTHHHHTHHHHHHHHHHHHHHHGGGBS?EEEEESSTTSHHHHHHHHHHTT?SEEEEEEEEETTEEEEEEEEES?? 3EVZ|A PF05972.6_APC_15aa_seed 9 16 !Q:0,6|11,15 Q:7,10 -??????TTTT????? 1JPP|C PF05974.7_DUF892_seed 111 178 !Q:30,33|64,71|84,84|89,89|91,91|95,95|128,136|138,138|163,163|165,169|172,177 Q:0,29|34,63|72,83|85,88|90,90|92,94|96,127|137,137|139,162|164,164|170,171 SHHHHHHHHHHHHHHHHHHHHHHHHHHHHH???-HHHHHHHHHHHHHHHHHHHHHHHHHHTSTT????????HHHHHHHHHHHH-HHHT-S?SSH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?--------H-HHHHHHHHHHHHHHHHHHHHHHHH-H-----HT?????? 3OGH|A PF05979.7_DUF896_seed 39 67 !Q:15,15|18,20|38,66 Q:0,14|16,17|21,37 SHHHHHHHHHHHHHH-HH???HHHHHHHHHHHHHHHHH??????????????????-?????????? 2HEP|A PF05980.7_Toxin_7_seed 30 34 !Q:0,0|3,3|7,9|14,15|17,17|20,21|33,33 Q:1,2|4,6|10,13|16,16|18,19|22,32 ?SB?TTS???SSSS??B?TT??EEEEETTEEEE? 2E2S|A PF05983.6_Med7_seed 33 299 !Q:0,170|192,214|217,221|225,227|229,232|238,239|258,258|298,298 Q:171,191|215,216|222,224|228,228|233,237|240,257|259,297 ?------------------------------------------------------------------------?----??-----------------------------------------------??-----------------------------------???????HHHHHHHHHHHHHHHHHHHHH-----------------------HT-----SSS???G----GGHHH--HHHHHHHHHHHHHHHHHH-THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH? 1YKH|A PF05985.6_EutC_seed 41 301 !Q:1,1|3,3|6,6|11,11|16,16|19,20|22,24|29,34|54,63|70,78|81,82|89,90|98,98|106,106|118,118|121,135|143,143|146,146|151,152|170,172|175,176|178,181|187,188|200,207|209,209|218,223|226,229|238,240|244,245|248,258|267,267|269,269|274,274|294,295|300,300 Q:0,0|2,2|4,5|7,10|12,15|17,18|21,21|25,28|35,53|64,69|79,80|83,88|91,97|99,105|107,117|119,120|136,142|144,145|147,150|153,169|173,174|177,177|182,186|189,199|208,208|210,217|224,225|230,237|241,243|246,247|259,266|268,268|270,273|275,293|296,299 S?S?HH-HHHH-HHHT?SS??S???BTTB----??HHHHHHHHHHHHHHHHHHH????------HHHHHH---------TT?-EEEEBS??SHHHHHH?HHHHTSB?HHHHHHHHHHS?SS--------------?SEEEEEE?TT?SHHH--HTTHHHHHHHHHHHHHT---TT??B???-EEEET??TTHHHHHHHHH--------T?SEEEEEEE????--SS????EEEEEEES-??TTT??GG-----------GEEEEEEE-S-TTSB?HHHHHHHHHHHHHHHHHHT??GGGS? 3ABQ|B PF05993.7_Reovirus_M2_seed 2 689 !Q:0,4|10,10|13,13|16,16|19,20|25,35|40,688 Q:5,9|11,12|14,15|17,18|21,24|36,39 ?????SSSSS?SS?TT?EE??BTTS???????????HHHH???????????--?????????---------------------------?????????????????????????????????????????????????????????????????????????-????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????---????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????-???--????????????????????????????????????????????????????????????????????????????????????????????????????????????----??????????????????--????????????????????????????????????????????????????????????????????????????????????? 1JMU|A PF05994.6_FragX_IP_seed 9 958 !Q:27,27|35,37|40,42|44,44|47,48|51,62|64,64|74,75|93,95|136,138|141,141|156,158|163,164|167,167|173,194|196,199|215,227|233,233|265,266|271,272|282,304|306,306|309,310|314,314|328,329|355,355|396,396|408,431|437,437|439,439|448,448|476,476|502,506|517,517|520,521|525,525|532,536|560,563|567,579|603,603|605,605|631,631|653,653|656,662|666,666|684,684|713,713|730,739|742,743|748,751|763,763|773,774|784,785|792,793|812,814|818,823|826,826|828,829|834,835|839,843|859,862|866,877|899,899|907,907|918,921|924,927 Q:0,26|28,34|38,39|43,43|45,46|49,50|63,63|65,73|76,92|96,135|139,140|142,155|159,162|165,166|168,172|195,195|200,214|228,232|234,264|267,270|273,281|305,305|307,308|311,313|315,327|330,354|356,395|397,407|432,436|438,438|440,447|449,475|477,501|507,516|518,519|522,524|526,531|537,559|564,566|580,602|604,604|606,630|632,652|654,655|663,665|667,683|685,712|714,729|740,741|744,747|752,762|764,772|775,783|786,791|794,811|815,817|824,825|827,827|830,833|836,838|844,858|863,865|878,898|900,906|908,917|922,923|928,957 HHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHS???TT---T?TT??TT------------S?HHHHHTGGG??HHHHHHHHHHHHHHHHH---HHHHHHTHHHHHHHHHHHHHHHHHHHHHTTTHHHHHHHHH---TT?HHHHHHHHHHHHHH???SSSS??TT?HHHHT????-------???????????S????HHHHHHHHHHHHHHH???-??????---TTTTS?HHHHHHHHHHHHHGGGHHHHHTHHHHHHHHS??GGGS??HHHHHHTTT-----------------------S?SS??GGG?HHHHHHHHHHHHT?-GGGTTTHHHHHTHHHHHHHHHHHTS?BHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS?HHHHHHHHHTT???---???----------?????HHHHT?S?EEETTEEE?HHHHHHHHHHHHHHHHHHHHHHHHHTS?GGGHHHHHHHHHHHHHHHHHHHTTS-????HHHHHHHHTT?SS--SSS?HHHHHH-----HHHHHHTHHHHEEEETTTTEEEE??--GGG?????????????GGGTTSSHHHHHHHHHHGGGGGS?B?HHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHTHHHHHHHHHHHHS?SB???--??GGG?HHHHHHHHHHHTHHHHS?TTTTTTHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHHHHGGGGT??????--??TT??HHHH----HHHHHHHTGGG?HHHHHHHHS-?HHHHHHHHH--HHHHHH??GGGTEESHHHHHHHHHTT?-?STT------TT?S??TTSS??SSB??---SHHHHHHHHHHHHHS???-TTS?----------?HHHHHBTHHHHHHHHHHHHTT?HHHHHHH?HHHHHHHHHH----HH????EETTEEHHHHHHHHHHHHHHHHHHHHHHHH 3P8C|A PF05995.7_CDO_I_seed 8 208 !Q:0,17|35,37|49,51|57,59|62,65|69,69|76,76|81,81|89,89|92,92|94,95|98,99|102,102|112,112|119,122|124,138|140,144|151,152|155,155|160,160|164,164|169,179|182,183|187,187|197,198|205,205 Q:18,34|38,48|52,56|60,61|66,68|70,75|77,80|82,88|90,91|93,93|96,97|100,101|103,111|113,118|123,123|139,139|145,150|153,154|156,159|161,163|165,168|180,181|184,186|188,196|199,204|206,207 ??---------???????SSHHHHHHHHHHHTTSS???HHHHHHHHHHS???HHHHG---GG????SSS?EEEEEE?GGGT?EEEEEEE?TT?B??EE??TT?EEEEEEEES?EEEEEE????S---------------S?????EEEEEE??TT?EEEE?TTT?EEEE-----------EE??SSS?EEEEEEEES??SEEEEE?TT 2GH2|A PF05996.7_Fe_bilin_red_seed 62 278 !Q:12,15|18,22|36,39|50,50|77,77|81,84|91,92|99,99|109,109|111,113|117,120|131,146|150,153|158,158|161,161|164,164|168,175|201,212|216,233|252,252|263,263|277,277 Q:0,11|16,17|23,35|40,49|51,76|78,80|85,90|93,98|100,108|110,110|114,116|121,130|147,149|154,157|159,160|162,163|165,167|176,200|213,215|234,251|253,262|264,276 HHHHHHHHHHHS--??EE?-???GGGSEEEEEETTE----EEEEEEEEEE?SSEEEEEEEEEEETTTEEEEEEEEEE?TTS-???EEEEEE--EEETTE-EEEEEEEEE?S---STT????HHHHHHHHHS?---------?--???SSB????TTGG-GS?TT?EEE?-----??SHHHHHHHHHHHHHHHHHHHHHHHH????-------?HHH------------------HHHHHHHHHHHHHHHHHH?THHHHHHHHH?HHHHHHHHHHTTS? 3AJG|A PF06001.8_DUF902_seed 8 42 !Q:7,7|9,13|16,19|22,22|28,28|31,31|34,34 Q:0,6|8,8|14,15|20,21|23,27|29,30|32,33|35,41 HHHHHTT?S?????EE????EE?SSSSS?EE?TT?EEEEETT 4BHW|A PF06002.7_CST-I_seed 7 305 !Q:0,1|7,8|14,16|20,21|35,35|41,41|50,50|70,70|78,81|83,83|88,88|94,98|107,107|113,113|118,118|124,124|134,138|152,153|160,171|173,176|183,183|187,197|214,214|220,220|230,230|232,244|247,249|251,253|255,259|270,304 Q:2,6|9,13|17,19|22,34|36,40|42,49|51,69|71,77|82,82|84,87|89,93|99,106|108,112|114,117|119,123|125,133|139,151|154,159|172,172|177,182|184,186|198,213|215,219|221,229|231,231|245,246|250,250|254,254|260,269 ??EEEEE??SGGGG???GGG??SSEEEEEETTGGG?SEETT?SEEEEEEE?GGGHHHHHHHHHHHHHTTS?EEEEEEE???-S?TTTS?HHHHH-----THHHHSTT?EETHH-HHTT?HHHHH-HHHHHHHHH?????HHHHHHHHHHHTT??EEEEES????-???????S????HHHHHH?GGG???????????HHHHHHHHHHHHHHHT?EEEES?TTSGGGGTS?B??---????????EE?-?S???S?????HHHHHHHGGG????????????????-?????????????????? 2P2V|A PF06003.7_SMN_seed 3 276 !Q:0,69|72,72|78,78|82,83|107,108|117,117|119,275 Q:70,71|73,77|79,81|84,106|109,116|118,118 ----------------------------------------------------???------?????????SS?EEEEE?TTT??EEEEEEEEEETTTTEEEEEETTT??EEEEEGGG?B???????????????????????????---------------------------------------------------------------------------------------------------------------------------------- 3PNW|C PF06004.7_DUF903_seed 30 51 !Q:0,0|9,9|13,13|16,17|20,20|24,24|30,30|33,33|35,35|40,40|50,50 Q:1,8|10,12|14,15|18,19|21,23|25,29|31,32|34,34|36,39|41,49 ?EEEEETTS?EEE?SS??EE?TTT?SEEEE?TT-S?EEEE?GGGEEEEEE? 2K57|A PF06005.7_DUF904_seed 35 95 !Q:0,1|59,74|92,95 Q:2,58|75,91 ??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH----------------HHHHHHHHHHHHHHHHH???- 2JEE|A PF06006.7_DUF905_seed 10 78 !Q:0,9|16,18|23,23|31,32|36,37|43,46|49,50 Q:10,15|19,22|24,30|33,35|38,42|47,48|51,77 ??????????HHHHHH---HHHH?TTEEEES-?SSS??EEEEE---?SS??EEEEEESSSTTHHHHHHHHHTTTTTTT 2HJJ|A PF06013.7_WXG100_seed 120 94 !Q:1,4|28,28|35,35|39,39|42,43|46,47|60,60|67,67|91,93 Q:0,0|5,27|29,34|36,38|40,41|44,45|48,59|61,66|68,90 T????HHHHHHHHHHHHHHHHHHHHHHH-HHHHHH-HHH-TT--TS?-HHHHHHHHHHHH-HHHHHH-HHHHHHHHHHHHHHHHHHHHHHT??? 2KG7|A PF06014.6_DUF910_seed 26 64 !Q:0,1|15,19|21,21|43,43|45,46|63,63 Q:2,14|20,20|22,42|44,44|47,62 ??SHHHHHHHHHTTT?????S?HHHHHHHHHHHHHHHHHTTSS?H--HHHHHHHHHHHHHHHH? 2NN4|A PF06016.6_Reovirus_L2_seed 4 1323 !Q:0,2|7,7|13,17|19,24|36,36|39,39|41,41|48,48|52,54|61,61|64,64|67,68|70,70|75,77|103,103|113,113|128,130|139,139|141,143|145,145|153,155|157,157|172,174|179,179|182,186|190,192|199,200|206,206|208,208|220,221|224,224|228,229|232,232|242,242|244,244|247,247|252,253|275,276|280,280|283,283|285,288|293,293|298,298|322,324|327,328|343,344|346,346|349,352|355,355|362,362|364,365|370,370|380,384|387,394|398,398|401,404|411,412|425,426|429,430|434,434|440,440|447,448|452,454|456,456|461,464|484,485|487,487|503,503|514,514|517,517|524,526|531,531|534,534|544,544|548,551|561,561|566,568|572,573|575,577|584,589|626,627|656,657|667,675|677,677|702,703|706,710|712,712|714,714|727,729|733,733|748,748|751,752|758,758|773,773|790,790|797,798|800,800|802,806|810,811|814,816|821,821|834,836|839,840|846,847|850,850|857,857|861,861|869,871|873,873|879,879|881,881|888,888|894,894|898,900|906,906|908,908|918,919|935,936|943,946|950,952|954,954|978,980|992,992|995,995|1000,1002|1005,1006|1017,1018|1035,1035|1044,1046|1049,1050|1052,1053|1058,1058|1066,1067|1070,1070|1089,1089|1091,1091|1113,1113|1116,1116|1141,1145|1150,1153|1156,1158|1162,1162|1170,1170|1174,1176|1179,1188|1198,1199|1207,1213|1218,1220|1226,1227|1232,1233|1242,1242|1246,1246|1252,1255|1259,1259|1263,1264|1266,1266|1270,1270|1285,1285|1288,1291|1294,1294|1297,1297|1300,1301|1308,1309|1313,1313|1316,1316|1322,1322 Q:3,6|8,12|18,18|25,35|37,38|40,40|42,47|49,51|55,60|62,63|65,66|69,69|71,74|78,102|104,112|114,127|131,138|140,140|144,144|146,152|156,156|158,171|175,178|180,181|187,189|193,198|201,205|207,207|209,219|222,223|225,227|230,231|233,241|243,243|245,246|248,251|254,274|277,279|281,282|284,284|289,292|294,297|299,321|325,326|329,342|345,345|347,348|353,354|356,361|363,363|366,369|371,379|385,386|395,397|399,400|405,410|413,424|427,428|431,433|435,439|441,446|449,451|455,455|457,460|465,483|486,486|488,502|504,513|515,516|518,523|527,530|532,533|535,543|545,547|552,560|562,565|569,571|574,574|578,583|590,625|628,655|658,666|676,676|678,701|704,705|711,711|713,713|715,726|730,732|734,747|749,750|753,757|759,772|774,789|791,796|799,799|801,801|807,809|812,813|817,820|822,833|837,838|841,845|848,849|851,856|858,860|862,868|872,872|874,878|880,880|882,887|889,893|895,897|901,905|907,907|909,917|920,934|937,942|947,949|953,953|955,977|981,991|993,994|996,999|1003,1004|1007,1016|1019,1034|1036,1043|1047,1048|1051,1051|1054,1057|1059,1065|1068,1069|1071,1088|1090,1090|1092,1112|1114,1115|1117,1140|1146,1149|1154,1155|1159,1161|1163,1169|1171,1173|1177,1178|1189,1197|1200,1206|1214,1217|1221,1225|1228,1231|1234,1241|1243,1245|1247,1251|1256,1258|1260,1262|1265,1265|1267,1269|1271,1284|1286,1287|1292,1293|1295,1296|1298,1299|1302,1307|1310,1312|1314,1315|1317,1321 ???BTTB?EEEEE?????B??????BHHHHHHHHHT?TT-S?SEEEEE?TTT?-?EEEEEE?SS?TT??S?HHHH???SSHHHHHHHHHHHHHHHHHHHHHHS?HHHHTTSBB?HHHHHHHHHHHTTT???GGGGGGSB?S---S?TTHHHHH???S?TTTEEEETTEEEEE???SEEE?SS????-TTS???TTTTSS??EEEEE?S?HHHHHHHGGGS??TT?EEE??SS?TTSSEEEEE?S?EE?SSTT??EEHHHHHHHHHHHHHHHHTTS??TTS?BS?S????EEEE?GGGS?TTSHHHHHHHHHHHHHHTEEESS???SS??HHHHHHHHHHHTSS??B?SS????TT?EEEETT?S??GGGT?SSSEEEETT?????EE????????BSS?EE????EEEEEE-?HHHHHHHHHHHB??SB??EEE?SEESS?EEEEEE??TTS?-?B?GGGS????TTTTSHHHHHHHHHHHHHB??S?HHHHHHHHHHHHHTT?EETTTTEESS?TT?EEEEET???TTTT?SS?TTHHHHHHT?STT????SEEEEESTT?SSSB???TTS??S???EEEEEE??????SSSTTHHHHHHHHHHHHHHHHHHEEEEEEEEEEESS??HHHHHHHHHHTGGGEEEEEEEEEESSSS??EEEEEEEES---??????B?HHHHHHHHHHHHHHHHHHHHHTTS??TT?---?B?S?SSSEEEEEEEES???SSS?SHHHHHHHHHHHHH?SS??EEEEE-EETTEEEEEEEEEE?HHHHHHHHTBSSEEEE?THHHHT??S?B?????EEE??SS???HHHH-HHHHHHHHHHHH??-TT??EEEES??SS?GGGGTS?TTS?EEEEESS???S?STTBS-S?EEEEES?TTSSS?GGG???SEEEE?S?HHHHHHHHT??HHHHHHHHHHHHHTS??SEEEEE????SSS???B-TTTBEEETTTTEEEETTTTEEEE???HHHHHHHHHHH?TT?EEEE???TT??GGGHHHHTTT??EEHHHHHHHHHHHTTS?EEEEETTS???EE-?S??BTTS?EEEEEES??TT?EEEEESSSSEEEEGGGTT-S?SSSEEEEEEETTTTEEEEEEE?SS?EEEEEEEEETTTTEEEEEEEEEEB?????EEEE??--SS???STT?EEEEEEE?TTS???EE----------EEETTEEEE??TTTEEEE???????EEEE???GGGGG??EEEE??SSSSSSSS?EEE?HHHHT????TTS?EEE??S-SSS?EEEEETTEEEEEET?TT????TT?EE?SS??SSSTTS??EEE?SS?EEEEE? 2CSE|U PF06018.9_CodY_seed 17 185 !Q:15,21|23,25|55,55|57,59|61,64|70,70|77,78|88,89|91,91|96,96|99,105|139,142|166,184 Q:0,14|22,22|26,54|56,56|60,60|65,69|71,76|79,87|90,90|92,95|97,98|106,138|143,165 HHHHHHHHHHHHHHS?----??S???HHHHHHHHHHHHTSEEEEEETTSBEEEEE?S---S????HHHHH-HHHHTB??HHHHHHHHT??S?EEEE?TT???????GGGGGGGSSSEEEEEEEEETTEEEEEEEEEESS????HHHHHHHHHHHHHHHHHHHHHHT?------------------ 2HGV|A PF06026.9_Rib_5-P_isom_A_seed 58 204 !Q:0,0|18,21|23,24|28,31|33,33|40,41|45,46|49,51|54,55|59,59|83,83|85,85|88,88|92,95|101,101|114,117|121,123|126,127|130,130|132,133|136,138|143,145|149,149|156,156|158,162|164,166|187,187|189,192 Q:1,17|22,22|25,27|32,32|34,39|42,44|47,48|52,53|56,58|60,82|84,84|86,87|89,91|96,100|102,113|118,120|124,125|128,129|131,131|134,135|139,142|146,148|150,155|157,157|163,163|167,186|188,188|193,203 ?EEEESSHHHHHHHHHTT?--?B??GGG?---S?EEEEEE??SEE?-TT-??EE??TTS?HHHHHHHHHTEEEEEEEEEGGGB?S-ST-TSS?--?EEEEE?GGGHHHHHHHGG----GGT?--EE--EE?B?-SS---SSSB???TTS?EEEEEE?S--??-S?--HHHHHHHHHTSTTEEEESEE?S?-??EEEEEETTEEE 1UJ5|A PF06028.6_DUF915_seed 13 261 !Q:0,10|17,18|21,22|35,35|39,39|41,41|43,43|47,48|52,52|55,56|62,68|70,70|81,85|105,107|131,131|135,135|145,146|149,150|156,156|161,161|163,163|166,167|171,172|190,190|199,200|204,204|224,224|246,246|259,260 Q:11,16|19,20|23,34|36,38|40,40|42,42|44,46|49,51|53,54|57,61|69,69|71,80|86,104|108,130|132,134|136,144|147,148|151,155|157,160|162,162|164,165|168,170|173,189|191,198|201,203|205,223|225,245|247,258 -----??????EEEEEE??TT??GGGTHHHHHHHH-TTT-S?S?EEE--EEE?SS??EEESS???????S?EEEEEESSTT?--??HHHHHHHHHHHHHHHHHTT???EEEEEEETHHHHHHHHHHHHHSS?SSS?EEEEEEEES??TT??TTTSS?TTTS?B?TT??BSS??HHHHHTGGGHHHHTTTT?EEEEEEEE??SSS?BSSSSBHHHHHTHHHHSTT?SSEEEEEEEESGGGSTGGGGG?HHHHHHHHHHHT?- 3FLE|A PF06029.6_AlkA_N_seed 90 216 !Q:0,0|4,5|7,8|10,12|24,25|32,59|61,62|64,74|84,89|91,95|97,118|120,120|128,136|140,145|153,157|159,161|169,169|183,184|193,198|205,205|208,213|215,215 Q:1,3|6,6|9,9|13,23|26,31|60,60|63,63|75,83|90,90|96,96|119,119|121,127|137,139|146,152|158,158|162,168|170,182|185,192|199,204|206,207|214,214 ?EEE--E??S???HHHHHHHHHHH??TTTEEE---------------------------?S--S-?---------EEEEEEETT------E-----E----------------------E-EEEEEEE---------TTT------TEEEEEE----?G---GGGGGHH-HHHHHHHHHHTTT??HHHHHHHH------THHHHS?TT??????S? 1PVS|A PF06032.7_DUF917_seed 51 483 !Q:1,3|21,21|23,24|35,35|43,43|45,45|50,50|52,52|55,60|64,64|73,75|79,85|89,89|91,96|98,99|115,115|119,121|127,127|141,142|149,149|155,155|160,161|173,173|175,183|185,185|190,190|194,207|215,225|244,244|255,255|263,264|283,285|288,288|300,311|321,338|345,363|366,366|384,395|398,398|411,411|415,419|425,425|431,431|445,447|453,455|471,475|477,482 Q:0,0|4,20|22,22|25,34|36,42|44,44|46,49|51,51|53,54|61,63|65,72|76,78|86,88|90,90|97,97|100,114|116,118|122,126|128,140|143,148|150,154|156,159|162,172|174,174|184,184|186,189|191,193|208,214|226,243|245,254|256,262|265,282|286,287|289,299|312,320|339,344|364,365|367,383|396,397|399,410|412,414|420,424|426,430|432,444|448,452|456,470|476,476 E--?GGGHHHHHHHHHHTTTT?S??HHHHHHHHTT?SBTTTBS?S?EEEE?G-GG?----?SSE-EEEEEEEE--?HHH-------HTT?S------S?-HHHHHHHHHHHHHHH-HTT??-EEEEE?SSSSHHHHHHHHH--HHHHHT?EEESB?SSSS??SSGGGSHHHHT-T???-----?S-EEEE?SSS-------------?EEEEEEE???????????HHHHHHHHHHHHTTSTTT?SEEEEEEEEE?HHHHHHH??SBSHHHHHHHHHHHHHTT???SH-HHHHHHHHHHH-????-------EEEEEEEEE????---??-????????EEEEES-------------------SS?EEEEEESSSEEEEEETT?-----------SS?SEETTSEEEEEE?SSS?????HHHHB?SSSSB?TTTTTSEEEEEEE???GGGSS---HHHHHHHHHHHHHTT--?-?S?????? 2O3I|A PF06035.6_Peptidase_C93_seed 28 179 !Q:6,24|28,32|37,37|41,46|58,60|64,68|71,72|75,77|85,85|100,100|103,104|119,119|127,127|132,132|136,136|139,139|142,142|148,148|153,159|162,162|166,178 Q:0,5|25,27|33,36|38,40|47,57|61,63|69,70|73,74|78,84|86,99|101,102|105,118|120,126|128,131|133,135|137,138|140,141|143,147|149,152|160,161|163,165 HHHHHH-------------------HHH-----HTTS?HHH------HHHHHHHTSEE???TTT-----SS??SS???HHHHTEE?HHHHHHHHHHHHHH-HT??GGGEEEEEETTTTE-EEEEEEE?STTS?EEE?SS?SS?EEGGG?TEEE------?SS?EEE????????-???? 4FGQ|A PF06041.6_DUF924_seed 154 293 !Q:6,18|21,22|25,30|32,32|34,34|37,38|52,54|58,58|65,68|70,76|82,82|84,95|115,117|126,126|144,145|147,148|151,151|154,159|173,175|191,217|220,249|267,267|276,279|289,292 Q:0,5|19,20|23,24|31,31|33,33|35,36|39,51|55,57|59,64|69,69|77,81|83,83|96,114|118,125|127,143|146,146|149,150|152,153|160,172|176,190|218,219|250,266|268,275|280,288 HHHHHH-------------HH?-HH------H-H-SS??HHHHHHHHHHHHH---HHH-HHHTTS---?G-------GGGGS-H------------HHHHHHHHHHTTHHHHHST---TSGGGTTT-HHHHHHHHHHHHHTTHH--H--HS?HH------HHGGGTHHHHTSS---SHHHHHHHHHHHTTT------?--------------------HH------------------------------HHHHHHHHHHHHHHHSS?GGGHHHHT????HHHHHHHHT-??? 2I6H|A PF06042.6_DUF925_seed 40 212 !Q:1,2|8,11|13,15|18,18|37,37|39,39|41,43|45,49|56,57|59,62|65,65|78,78|81,81|83,85|90,93|108,118|135,135|139,153|157,158|162,162|165,165|175,178|184,184|198,199|204,204|207,207|210,211 Q:0,0|3,7|12,12|16,17|19,36|38,38|40,40|44,44|50,55|58,58|63,64|66,77|79,80|82,82|86,89|94,107|119,134|136,138|154,156|159,161|163,164|166,174|179,183|185,197|200,203|205,206|208,209 H--HHHHH----T??-SS?EEETHHHHHHHHGGGTTS?T-T???S-----EEEEEE??T----TS?HHHHHHHHHHHH-HH?T---TSEE----EEEESTTTTSSSSS?-------???SSHHHHHTTSSSTTTS?EEE??-------------TTS??EEE?TT?THHHHTTEE???-HHHHT?HHHHHHHHHHHHT??HHHH?TT?EE?? 2LA3|A PF06043.6_Reo_P9_seed 4 353 !Q:0,7|10,10|13,17|30,33|46,51|66,67|74,74|77,79|107,149|153,153|160,161|168,169|173,173|177,177|181,185|213,215|221,221|246,250|259,259|262,262|271,271|274,278|289,289|294,306|308,309|313,313|317,317|321,323|327,331|334,337|341,345|349,352 Q:8,9|11,12|18,29|34,45|52,65|68,73|75,76|80,106|150,152|154,159|162,167|170,172|174,176|178,180|186,212|216,220|222,245|251,258|260,261|263,270|272,273|279,288|290,293|307,307|310,312|314,316|318,320|324,326|332,333|338,340|346,348 ????????TT?EE?????SSSSSSSSSSSS----SSSSSSSSSSSS??????EETHHHHHHHHHHT??GGGSTT?SS???SSTTHHHHHHHHHHHHHHHHHHHHSSS???????????????????????????????????????????EEE?TTTTEE??EETTEE??EES?GGG?SSS?????HHHHHHHHHHHHHHHHHHHHHHHHHHT???TTGGG?BSGGGHHHHHHHHHHHHHHHHTSS?????HHHHHHHH?TT?BHHHHHHH?SS?????HHHHHHHHHS?SEEE?????????????E--EEE?SSS?EEE???EEE?????SS????TTS?????TTS???? 3VJJ|A PF06044.7_DRP_seed 6 259 !Q:0,2|4,5|15,15|31,33|37,38|41,41|44,51|55,55|59,60|69,71|74,75|94,96|104,105|117,117|121,122|133,140|152,152|156,156|166,167|185,185|187,187|204,204|227,227|229,229|250,250|258,258 Q:3,3|6,14|16,30|34,36|39,40|42,43|52,54|56,58|61,68|72,73|76,93|97,103|106,116|118,120|123,132|141,151|153,155|157,165|168,184|186,186|188,203|205,226|228,228|230,249|251,257 ???B??HHHHHHTTT?TTHHHHHHHHHHHHH???TTT??SS?EE????????EEE?TTT??EEEEEEEE---SS??SEEEEEEHHHHHHHHHTT???EEEEEEE-?TTSBEEEEEEE?GGG??GGGEEEEEEE????????EEEEEEEGGGS?GGG?EEEEETTEE??HHHHHHHHHHTGGGGGS?H-HHHHHHHHHHHHHHHS?SSEEEHHHHHTTHHHHHHHSTT?S?HHHHHHHHHHHHHHTTSEEE?STTEEEE? 4ESJ|A PF06046.8_Sec6_seed 38 814 !Q:0,285|290,290|323,327|329,330|332,351|353,353|357,370|373,373|391,393|398,398|445,470|474,476|478,478|496,505|519,519|524,524|556,556|558,559|569,570|572,575|581,591|605,605|613,613|617,617|640,655|682,683|705,709|712,712|717,740|751,751|754,755|758,763|772,772|775,776|803,808|813,813 Q:286,289|291,322|328,328|331,331|352,352|354,356|371,372|374,390|394,397|399,444|471,473|477,477|479,495|506,518|520,523|525,555|557,557|560,568|571,571|576,580|592,604|606,612|614,616|618,639|656,681|684,704|710,711|713,716|741,750|752,753|756,757|764,771|773,774|777,802|809,812 ----------------------------------------------------------------------------------------------------------------------------------------?-------------------------------------------?----------?-----------?---------------------------------------------------------------------------------?HHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---??S??E--------------------E?TTS-------------?EE?HHHHHHHHHHHHHHHHH---HHTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTGGGS------------------------??TTT???S?HHHHHHHHHHHHHHHHH----------HHHHHHHHHHTTS?HHHH-HHHHHHHHTTHHHHHHHHHHHHHHHHHHHHH-T--THHHHTTTT--S----GGGTT?---------?HHHHHHHHHHHHH-HHHGGGS?HHH-HHHHHHHHHHHHHHHHHHGGGG----------??????GGGHHHHHHHHHHHHHHHHHHHHTTT-?TTHHHHHHHHHHHHHHHHHHH-----HS?GGGH------------------------HHHHHHHHTT?TT??SH------HHHHHHTT?TT??HHHHHHHHHHHHHHHHHHHHHHHHTT??????GGGG? 2FJI|1 PF06050.8_HGD-D_seed 163 510 !Q:0,0|3,5|13,13|15,16|18,20|24,41|43,46|53,54|58,58|67,75|79,97|104,104|106,106|108,109|111,112|115,115|126,127|133,133|135,140|142,149|151,151|156,158|160,160|165,175|177,182|193,193|195,204|216,218|223,225|239,239|248,250|258,258|260,260|265,265|274,274|276,276|295,297|299,312|322,322|324,329|333,333|339,339|353,358|366,377|379,379|381,388|392,392|400,402|404,406|410,414|417,417|432,433|443,443|448,461|475,475|477,478|485,485|487,490|492,496 Q:1,2|6,12|14,14|17,17|21,23|42,42|47,52|55,57|59,66|76,78|98,103|105,105|107,107|110,110|113,114|116,125|128,132|134,134|141,141|150,150|152,155|159,159|161,164|176,176|183,192|194,194|205,215|219,222|226,238|240,247|251,257|259,259|261,264|266,273|275,275|277,294|298,298|313,321|323,323|330,332|334,338|340,352|359,365|378,378|380,380|389,391|393,399|403,403|407,409|415,416|418,431|434,442|444,447|462,474|476,476|479,484|486,486|491,491|497,509 ?SS???HHHHHHT-T?-E---EEE--?-----------???-S???-SGGGGT??TTS?HHHHHHHH---------HHH-------------------TTTTTT?S?E--E--EE?SSHHHHHHHH--HHHHH?T------T--------S?EEEE???S?TTSH-----------H------HHHHHHHHHH-H----------HHHHHHHHHSS???HHHH---HHHHHHHHHHHHH-HHHHHHHH---HHBTTTS?H-HHHH-HHHHGGGS-S?HHHHHHHHHHHHHHHHTS?-?B------------??SSEEEEEEE-S??--??HHH-HHHHH-HTTEEEEEEEETT------TGGGTSS?????-------S?H--------HHH-HHHHHHH?-?S?--TTS?---?TT?THHHHHHHHHHHTT??EEEEEEETT?HHHH--------------HHHHHHHHHHHHT-T??EEEEEE?S----S?????HHHHHHHHHHHHT 3O3N|A PF06052.7_3-HAO_seed 5 156 !Q:0,0|2,5|24,24|30,31|40,40|44,45|47,47|51,51|54,54|63,63|71,71|76,76|84,84|92,92|95,96|102,102|105,105|113,115|119,120|126,126|130,131|138,139 Q:1,1|6,23|25,29|32,39|41,43|46,46|48,50|52,53|55,62|64,70|72,75|77,83|85,91|93,94|97,101|103,104|106,112|116,118|121,125|127,129|132,137|140,155 ?S????EEHHHHHHHHGGGGSSSS?EEEEE-?SSEEEEEE?SSB??S?EEE?SS?EEEEEEES?EEEEEEE?SSSS?EEEEEEE?TTEEEEE?TT??EEEEE?TT?EEEEEEE???SSS??EEEEE?TTT??EEEEEE??SSSTTHHHHHHHHHHH 1YFY|A PF06058.8_DCP1_seed 9 131 !Q:8,10|19,19|63,63|71,76|81,82|85,85|98,102|105,107 Q:0,7|11,18|20,62|64,70|77,80|83,84|86,97|103,104|108,130 HHHHHHHH---HHHHHHHH?TTEEEEEEEEEEEEEEEEETTTTEEEEEEEEEEEEEEEESSSS?EEEEEEE??????EEEE??TT?EEEEETTEEEEE----?TT?-?EEEEEESSHHHHHHHHHHHHHHH 2LYD|A PF06064.6_Gam_seed 2 98 !Q:0,19|39,39|56,57|68,68|96,97 Q:20,38|40,55|58,67|69,95 ????????????????????HHHHHHHHHHHHHHHHHTS?THHHHHHHHHHHGGGT??HHHHHHHHHH?HHHHHHHHHHHHHHHHHHHHHHHHHHH?? 2UV1|A PF06068.8_TIP49_seed 16 488 !Q:7,8|10,17|19,19|23,87|89,89|94,102|107,107|125,126|129,129|135,136|153,154|158,158|168,169|173,173|207,224|241,241|253,254|266,267|278,279|283,285|292,295|297,297|316,316|318,348|368,368|378,378|395,396|403,404|409,409|415,415|421,422|434,438|455,456|458,458|473,473 Q:0,6|9,9|18,18|20,22|88,88|90,93|103,106|108,124|127,128|130,134|137,152|155,157|159,167|170,172|174,206|225,240|242,252|255,265|268,277|280,282|286,291|296,296|298,315|317,317|349,367|369,377|379,394|397,402|405,408|410,414|416,420|423,433|439,454|457,457|459,472|474,487 HHHTTTT??S??------B?TTS----------------------------------------------------------------?B?SEET---------TEES?HHHHHHHHHHHHHHHTT??TT?EEEEE??TTSSHHHHHHHHHHHH?-TTS?EEEEEGGGG??SSS?HHHHHHHHHHHTEEEEEEEEEEEEEEEEEEEEE??-??????-????????EEEEEEETTEEEEEEE?HHHHHHHHHTT??TTEEEEEETTT??EEEEEEETTS??TTS?--SSSSEE????S?SEEEEEEEEEEEHHHHHH-T???????????????????????????????HHHHHHHHHHHTTSEEEEE?EEEEESGGG?BHHHHHHHHHHTTSTT??EEEEEE??SEEE?BTTSS?EEETT??HHHHTTEEEEE?????HHHHHHHHHHHHHHHT??B?HHHHHHHHHHHHHS?HHHHHHTHHHHHHH 3UK6|A PF06071.8_YchF-GTPase_C_seed 44 88 !Q:7,7|20,20|30,30|37,38|44,44|52,52|54,56|66,67|71,71|74,74|76,77|80,80|87,87 Q:0,6|8,19|21,29|31,36|39,43|45,51|53,53|57,65|68,70|72,73|75,75|78,79|81,86 EEEEEEE?SSEEEEEEEETT?BHHHHHHTT?TTHHHH??EEEEE?HHHHHHT-T---SHHHHHHTT??EEE?TT?B??TT?EEEEES? 1JAL|A PF06078.6_DUF937_seed 89 346 !Q:6,103|113,119|125,131|135,140|144,181|183,183|187,210|220,258|267,268|272,290|299,304|315,317|320,321|323,324|343,343|346,346 Q:0,5|104,112|120,124|132,134|141,143|182,182|184,186|211,219|259,266|269,271|291,298|305,314|318,319|322,322|325,342|344,345 HHHHHH--------------------------------------------------------------------------------------------------HHHHTTTTH-------HHHHH-------HHH------HHT--------------------------------------T?HHH------------------------HHHHHHHTT?--------------------------------------HHHHHHHH?-SSS?????-------------?HHHHHHHH-?----HHHHHHHHHH---HT??H--HHHHHHHHHHHHHHHHHT?TT- 1Z67|A PF06079.6_Apyrase_seed 20 321 !Q:0,0|6,7|11,12|14,14|31,32|38,38|41,42|48,48|55,57|76,76|85,86|94,94|101,101|104,118|120,123|136,137|140,140|143,143|146,147|151,151|160,160|163,164|170,170|179,179|184,185|188,189|193,193|195,195|208,209|216,218|225,225|227,228|234,234|239,239|245,245|247,251|262,262|268,268|278,283|286,287|300,300|309,309|320,320 Q:1,5|8,10|13,13|15,30|33,37|39,40|43,47|49,54|58,75|77,84|87,93|95,100|102,103|119,119|124,135|138,139|141,142|144,145|148,150|152,159|161,162|165,169|171,178|180,183|186,187|190,192|194,194|196,207|210,215|219,224|226,226|229,233|235,238|240,244|246,246|252,261|263,267|269,277|284,285|288,299|301,308|310,319 ?GGGGB-?SST--T?EEEEEEEEEEEEETTS??EEEEE?SS-?EEEEE?EEETTB???EEEEEEETTEEEEEETTT?EEEEEETT--EEEEEEE?BSTTTT?SS---------------B????EEEEETTEEEEE??SS?EE?SS??EEE?GGGEEEEE?TT??EEEEE?HHHHHHHH-HHTT??TT-?EEE?S?EEEETTTTEEEE??SEEESS???TTTGGG?B??EEEEE?TTSS?EEEEE?S--???TTEEEEEEEE?TTSTT?EEEEEEEEE-----?SS?-EEEEEEEEETTS?EEEEEEEE-ESSEEEEEEE? 1S1D|A PF06083.6_IL17_seed 20 105 !Q:5,7|14,20|22,22|25,25|37,37|42,42|45,45|47,47|53,53|65,90|102,102|104,104 Q:0,4|8,13|21,21|23,24|26,36|38,41|43,44|46,46|48,52|54,64|91,101|103,103 HHBSS--?EEEEEE-------E?SS?TTSEEEEEEES?SSEE?TT-S?EETTS-EEEEEEEEEEE????------------??????????EEEEEEEEEEE-E? 2VXS|A PF06087.7_Tyr-DNA_phospho_seed 27 593 !Q:2,2|7,8|12,12|15,21|26,26|28,28|38,39|47,51|53,53|55,55|64,64|71,73|79,84|97,99|101,101|109,112|116,120|122,124|133,137|139,141|147,149|158,161|164,164|169,171|173,175|177,178|180,180|182,197|200,200|213,220|234,235|238,242|249,249|256,263|269,270|284,293|300,300|302,302|306,306|308,308|310,313|330,331|334,365|368,372|377,378|389,390|397,400|403,406|416,417|422,425|427,438|442,442|446,446|448,449|456,466|480,481|488,488|490,495|506,506|515,520|526,544|550,578|580,581|584,585|588,589|591,592 Q:0,1|3,6|9,11|13,14|22,25|27,27|29,37|40,46|52,52|54,54|56,63|65,70|74,78|85,96|100,100|102,108|113,115|121,121|125,132|138,138|142,146|150,157|162,163|165,168|172,172|176,176|179,179|181,181|198,199|201,212|221,233|236,237|243,248|250,255|264,268|271,283|294,299|301,301|303,305|307,307|309,309|314,329|332,333|366,367|373,376|379,388|391,396|401,402|407,415|418,421|426,426|439,441|443,445|447,447|450,455|467,479|482,487|489,489|496,505|507,514|521,525|545,549|579,579|582,583|586,587|590,590 TT?EEEB??TTS?GG-------GTTT?B?HHHHHSGGG??EEEEEEE----?S?B?HHHHHHHS?GGGTTS--?EEEEE?---??HHHHHHHHHHHT---T?TTEEEEE????STT---??B???EEEEEESS?----E---EEEEE???BSGGGGTS----SB?EEEE???B--?B??T-T??????---------?TT?HHHHHHHHHHTT?------?HHHHHHHHHHHTB??TT?---?SEEEEE?SEEEET--------TGGGS--SHHHHHHHHHHHH????------TTGGGS?E-EEE?S?B????SSTTTTTTTHHHHHHT??SS----------------------------????TT?????EEEE??BHHHHHTSSS-?GGGGGG????HH----HHGGGGGGG--GGEE????G------------GGT?TTS?B??EEEEEE?----------TTSSEEEEEEEES??BSHHHH?E------EETTTTEEEE?SBEEEEEE-----?GGGGT------------------?SSEEB??????---------------????????B??SS?-SS??B?? 3SQ7|A PF06088.6_TLP-20_seed 21 257 !Q:0,10|18,18|21,23|32,32|34,34|38,40|42,42|50,52|64,65|79,80|83,83|86,87|96,96|100,100|103,103|112,256 Q:11,17|19,20|24,31|33,33|35,37|41,41|43,49|53,63|66,78|81,82|84,85|88,95|97,99|101,102|104,111 ??????????-EEEEEEE?SS--?TTEEEEEE?S?EEE???S?EEEEEEE???GGGGGGGTSEE--EEEESSSEEEEEE??SS?SS??EEEEEESS?EEE?TT?EEEEEEEE?------------------------------------------------------------------------------------------------------------------------------------------------ 1TUL|A PF06090.7_Ins_P5_2-kin_seed 38 693 !Q:4,4|7,9|16,16|18,47|62,77|79,79|89,89|95,95|108,109|114,115|119,119|121,123|126,129|135,137|145,146|152,174|178,178|185,186|190,190|193,193|201,201|204,261|267,271|273,276|278,299|302,302|307,308|314,314|324,340|346,346|349,353|356,358|362,366|368,369|383,390|406,406|410,415|425,438|445,450|466,512|526,526|541,560|563,565|568,583|587,587|607,607|614,652|654,655|660,661|663,663|670,677|686,686 Q:0,3|5,6|10,15|17,17|48,61|78,78|80,88|90,94|96,107|110,113|116,118|120,120|124,125|130,134|138,144|147,151|175,177|179,184|187,189|191,192|194,200|202,203|262,266|272,272|277,277|300,301|303,306|309,313|315,323|341,345|347,348|354,355|359,361|367,367|370,382|391,405|407,409|416,424|439,444|451,465|513,525|527,540|561,562|566,567|584,586|588,606|608,613|653,653|656,659|662,662|664,669|678,685|687,692 EEEE?SS---EEEEEE?S??----------------------------TTTTTEEEEEEEEE???????????????-S?HHHHHHTTT?HHHHT?SSHHHHHHHHHH--HTTH--HHH?T---TS????EEEEE?--HHHHHHH--HHHHG-----------------------GGS?HHHHHH--EEE?TT?SEEEEEE?TT?????????----------------------------------------------???EEEEE?????S????T----------------------TS?GGGG--GGGTS?HHHHHHHHH-----------------HHTTS?SS?????HH---HHT-----T??HHHHHHHHHHHHH?------?TTTEEEEETTEEEES?SSS??????HHHHHHHHH--------------HTBTTB??????HHHHHHHHHHHHHHH-----------------------------------------------HTHHHHHHHHHTT?SSHHHHHHHHHHHH--------------------TT???TT??????????---???TTS?HHHHHHHHHHHHHHHHHHT?EEEEEE???????????-------------------------???B??TTTT??B?EEEEEE?????--?GGGHHHHH-HHHHHH 2XAO|A PF06093.8_Spt4_seed 37 81 !Q:7,7|19,20|28,29|31,31|33,33|44,44|53,53|57,58|66,67|71,71|80,80 Q:0,6|8,18|21,27|30,30|32,32|34,43|45,52|54,56|59,65|68,70|72,79 EEEETTT?BEEEHHHHHHH??TTTHHHH??T-T?HHHHHHHEES?EEEEEEES?GGG-?HHHHHTT-?TTS?SEEEEEEE? 3H7H|A PF06094.7_AIG2_seed 90 203 !Q:3,6|13,13|22,22|26,31|43,47|49,49|64,75|80,109|111,112|116,116|121,124|126,129|132,133|143,149|153,153|155,155|164,169|174,180|184,194 Q:0,2|7,12|14,21|23,25|32,42|48,48|50,63|76,79|110,110|113,115|117,120|125,125|130,131|134,142|150,152|154,154|156,163|170,173|181,183|195,202 EEE?---STTSTT-STTTHHHH?GGG?----?EEEEEEEEESS----?B?EEEETTTTEEEEES-----------?TTSS------------------------------B??EEE-EEEE---?H----HH--HHHHHHHTT-------TTT-S?EEEEEEEE------EEEE???????SEE-----------EEEEEEES 2PN7|A PF06100.6_Strep_67kDa_ant_seed 8 509 !Q:2,2|8,9|25,27|35,35|38,54|58,61|63,64|67,67|79,79|99,102|104,105|114,114|119,122|127,127|137,137|144,144|151,151|169,170|195,195|198,198|200,201|204,204|222,222|226,226|251,251|261,262|271,273|278,278|281,281|286,296|309,309|313,314|322,323|327,328|336,336|351,351|357,357|362,362|368,368|371,371|376,377|380,380|385,386|389,389|398,398|402,403|407,407|409,409|413,414|428,429|449,449|458,460|465,465|469,469|484,487|490,492 Q:0,1|3,7|10,24|28,34|36,37|55,57|62,62|65,66|68,78|80,98|103,103|106,113|115,118|123,126|128,136|138,143|145,150|152,168|171,194|196,197|199,199|202,203|205,221|223,225|227,250|252,260|263,270|274,277|279,280|282,285|297,308|310,312|315,321|324,326|329,335|337,350|352,356|358,361|363,367|369,370|372,375|378,379|381,384|387,388|390,397|399,401|404,406|408,408|410,412|415,427|430,448|450,457|461,464|466,468|470,483|488,489|493,508 SS?EEEEE??SHHHHHHHHHHHHTT???GGGEEEE?SS?????????????????GGG????B-?TT?HHHHHHHTSSB?SSSTTSBHHHHHHHHHHHS????S??EEETTTEE?TTTT????TTHH-HHHHHHHTS?GGGGTT?BHHHHS?HHHHHSHHHHHHHHHHT??TTSBHHHHHHHHHHTGGGTTSSTT?TT?B??SS?HHHHTTHHHHHHHHHTT?EEE?SEEEEEEEEEEETTEEEEEEEEEE-ETTEEEEEE??TTEEEEEE???SSTT?EE?BTTB????????--?HHHHHHHHHHHH?GGG??THHHHSS??TTS??EEEEEEE?SSSSHHHHHHHHSS?TTSSS?SSSS?EEETT?TT?EEEE??SS?SSTT??TT?EEEEEEES?SSS??SSS?S?GGG??HHHHHHHHHHHTT??TTTHHHHHSTTTEEEEEEE?TTTTGGGS???TTSS?BSS?TTBSSEEEESTTSB?---SS???SSSHHHHHHHHHHHHH 4IA5|A PF06106.6_DUF950_seed 3 112 !Q:0,1|16,17|20,22|36,36|48,48|57,57|65,65|75,75|83,83|86,87|94,95|98,99|101,103|110,111 Q:2,15|18,19|23,35|37,47|49,56|58,64|66,74|76,82|84,85|88,93|96,97|100,100|104,109 ??HHHHHHHHHHHHHT??SS???EEEEEEEEHHHHS?TTTSSSSTTTT?EEEEEEEE?HHHHHTT?EEEEEESSS?EEEEEEE?TT??EEEEEE??SS??S???HHHHHT?? 2KCD|A PF06108.7_DUF952_seed 102 159 !Q:16,18|24,26|32,32|34,34|38,43|46,46|56,60|66,71|75,76|78,78|81,82|84,97|103,119|122,122|129,136|141,147|153,154 Q:0,15|19,23|27,31|33,33|35,37|44,45|47,55|61,65|72,74|77,77|79,80|83,83|98,102|120,121|123,128|137,140|148,152|155,158 EEEHHHHHHHHHHTEE???HHHHH---HSSEE?B?HHH------HH-HHHHHTSTT---??SEEEE------EEE??S?TT--T--------------EEEEE-----------------GG-GSSEEE--------EESS------?EEGGG??EEEE 2JQN|A PF06109.8_HlyE_seed 2 299 !Q:0,5|32,32|100,101|184,184|263,264|267,267|288,298 Q:6,31|33,99|102,183|185,262|265,266|268,287 ??????THHHHHHHHHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS??TTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGGGSS?HHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??TT?HHHHHHHHHHHHHHHHHHHH??????????? 1QOY|A PF06110.6_DUF953_seed 6 136 !Q:14,24|36,37|39,40|44,44|64,65|68,71|79,81|87,87|95,96|99,101|113,114|116,117|119,119|125,125|135,135 Q:0,13|25,35|38,38|41,43|45,63|66,67|72,78|82,86|88,94|97,98|102,112|115,115|118,118|120,124|126,134 EEEHHHHHHHHHHH-----------TSSSEEEEEEB??B?-TTS?BSSHHHHHHHHHHHHHHHH-?SS---?EEEEEEE???HHHHT?TTSHHHH--TS???SSSEEEEETSS-?E--E?HHHHH?HHHHHHHHH? 1WOU|A PF06114.8_DUF955_seed 77 204 !Q:2,2|5,5|11,24|27,28|34,58|69,69|71,71|91,91|96,113|120,121|143,143|155,155|161,183|193,194 Q:0,1|3,4|6,10|25,26|29,33|59,68|70,70|72,90|92,95|114,119|122,142|144,154|156,160|184,192|195,203 HT?TT?EEEEE?------------?TT??EEEET-------------------------TTTEEEEESS-S?HHHHHHHHHHHHHHHHHHH?HHHH------------------HHHHHH??THHHHHHHHHHHHHHHHHHHS?HHHHHHHHHHH?SSHHH-----------------------HHHHHHHHT??HHHHHHHHH 3DTI|A PF06124.6_DUF960_seed 11 104 !Q:0,0|12,12|24,27|36,38|61,64|73,74|78,80|88,88|91,91|94,97|100,100 Q:1,11|13,23|28,35|39,60|65,72|75,77|81,87|89,90|92,93|98,99|101,103 ?EEEEHHHHTTS?HHHHHHHHHHH----HHHTBTTB???SEEEEEEEEETTEEEEEEEETT????EEEEEEEE??TTS--?SEEEEEE?SS?EE----EE?GGG 2R41|A PF06125.6_DUF961_seed 12 108 !Q:0,1|4,4|7,8|12,12|14,14|28,28|32,32|38,38|47,47|51,53|64,69|72,72|79,79|82,82|89,91|93,96|98,98|102,102|104,104 Q:2,3|5,6|9,11|13,13|15,27|29,31|33,37|39,46|48,50|54,63|70,71|73,78|80,81|83,88|92,92|97,97|99,101|103,103|105,107 ??SS?SS??GGG?S?EEEEEEEEEEEEE?TTS?EEEEE-EEEEEEEE?SSS-??EEEEEEETTS??????TT?EEEESS?EE?SSHHHH??-S-???S?EEE?S?EEE 2K5D|A PF06133.6_DUF964_seed 233 111 !Q:0,0|45,68 Q:1,44|69,110 ?HHHHHHHHHHHHHTSHHHHHHHHHHHHHHHSHHHHHHHHHHHHH????-???????????--??????HHHHHHHHHTSHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHH 2OEQ|A PF06134.6_RhaA_seed 5 417 !Q:0,3|18,19|30,32|43,62|64,67|86,87|96,98|102,104|108,109|125,125|131,133|143,143|147,147|177,177|183,186|191,192|194,194|211,211|213,215|225,226|228,229|232,232|239,239|252,252|262,262|265,266|278,278|280,280|286,286|288,288|293,294|296,298|300,300|315,315|324,328|331,331|354,354|366,366|381,381|396,397|416,416 Q:4,17|20,29|33,42|63,63|68,85|88,95|99,101|105,107|110,124|126,130|134,142|144,146|148,176|178,182|187,190|193,193|195,210|212,212|216,224|227,227|230,231|233,238|240,251|253,261|263,264|267,277|279,279|281,285|287,287|289,292|295,295|299,299|301,314|316,323|329,330|332,353|355,365|367,380|382,395|398,415 ????HHHHHHHHHHHTTT??HHHHHHHHTT???EEEGGGGTTS????????????????????S????SHHHHHHHHHHHHTTSSS??EEEEEGGG???SSS???GGG??GGGGHHHHHHHHHHT?EEEEE???SSSGGGTTS?STT?SSHHHHHHHHHHHHHHHHHHHHHHHHHTS?EEEEE????EESS??S?SHHHHHHHHHHHHHHH?S???TTTEEEEEE??S??TT?SSEESS?HHHHHHHHHHTT?EEEEETTSS?TT??SHHHHHHHHTT?S?EEEEE?B?SSSS??B???S?HHHHHHHHHHHHTT?TTTEEEEE?????SS?HHHHHHHHHHHHHHHHHHHHTS?HHHHHHHHHTT?HHHHHHHHHHGGGS?HHHHHHHHHHHTTS??TTTHHHHHHHHHHHTGGG? 1D8W|A PF06140.8_Ifi-6-16_seed 27 89 !Q:4,5|8,10|25,25|37,37|40,43|47,47|52,52|67,68|77,77|83,83|88,88 Q:0,3|6,7|11,24|26,36|38,39|44,46|48,51|53,66|69,76|78,82|84,87 HHHS-?HH---HHHHHHHHHHTSSS?SHHHHHHHHHH?SS????TTT?SSSS?STHHHHHHHHHHHH--HHHHHHHH?SSSSS?SSSS? 2LOQ|A PF06141.6_Phage_tail_U_seed 8 134 !Q:0,1|18,19|28,29|32,34|38,38|54,57|70,75|93,94|114,114|118,120|133,133 Q:2,17|20,27|30,31|35,37|39,53|58,69|76,92|95,113|115,117|121,132 ?-HHHHHHHHHHHHHHHH-?TTSEEEES??SS??-TTT?SEEEEEEEEEEEEEE????EEEEEEEEEEEE??????HHHHHHHHHHHTHHHHT??HHHHTTEEEEEEEEEEEEE?SSS???EEEEEEEEEEEE? 3FZ2|A PF06144.8_DNA_pol3_delta_seed 24 190 !Q:6,6|26,29|34,35|39,39|43,44|51,53|56,59|65,75|78,80|93,95|106,110|125,127|129,129|135,142|159,159|162,162|174,174|176,176 Q:0,5|7,25|30,33|36,38|40,42|45,50|54,55|60,64|76,77|81,92|96,105|111,124|128,128|130,134|143,158|160,161|163,173|175,175|177,189 EEEEES?HHHHHHHHHHHHHHHTTTT????EEEE??TTS?HHH--HHHHHH???TT????EEEEE??---------SS???STHHHHHHHTTS???TTSEEEEEES--???TTGGGSTHHHHHTT---T?EEEEE???----?TTTHHHHHHHHHHHTT?EE?HHHHHHHHHTT?S?HHHHHHHHHHHHH 1XXH|A PF06150.7_ChaB_seed 56 76 !Q:1,1|8,9|27,30|37,38|61,61|65,68|70,71|74,75 Q:0,0|2,7|10,26|31,36|39,60|62,64|69,69|72,73 S?HHHHTT??SHHHHHHHHHHHHHHHH?--?SSSSSS?-HHHHHHHHHHHHHHHHHHHEEE?SSS?---E--EE?? 1SG7|A PF06153.6_DUF970_seed 11 109 !Q:0,0|24,25|64,65|71,87|93,94|102,102|108,108 Q:1,23|26,63|66,70|88,92|95,101|103,107 -EEEEEEEEHHHHHHHHHHHHHTT??EEEEEEEETTTTEEEEEEEEEEEGGGHHHHHHHHHHHH??EEEEE?????????????????EEEEE??EEEEEEE?SEEEE? 3M05|A PF06154.6_YagB_YeeU_YfjZ_seed 10 105 !Q:3,5|7,10|28,29|38,40|68,68|72,74|88,88|91,91|102,104 Q:0,2|6,6|11,27|30,37|41,67|69,71|75,87|89,90|92,101 TTS???S????SSSEEEEEEEEETTEEE??GGGEEEES???HHHHHHHHHHHHHHHHHHHHHHHHTSS?TTS???EEEEETTEEEEEE?TT?SSEEEEEEEE??? 2EA9|A PF06155.7_DUF971_seed 109 147 !Q:7,7|10,10|21,40|42,52|64,64|66,66|71,84|87,88|90,111|114,115|136,139|147,147 Q:0,6|8,9|11,20|41,41|53,63|65,65|67,70|85,86|89,89|112,113|116,135|140,146 EEEEEEG-GG-TEEEEEETTS?-------------------E-----------EEEEHHHHHHS?S?SSSS--------------SS--S??--------------??????SS??EEEEEEETTTEEEEEETTTB????EEHHHHH- 3O2G|A PF06165.6_Glyco_transf_36_seed 116 132 !Q:1,2|4,6|11,12|18,18|25,28|30,36|41,42|46,46|57,62|73,75|78,82|94,94|98,98|105,106|110,110|114,114|121,121|129,129 Q:0,0|3,3|7,10|13,17|19,24|29,29|37,40|43,45|47,56|63,72|76,77|83,93|95,97|99,104|107,109|111,113|115,120|122,128|130,131 T??B???EEEE--TTEEE?TTSTTT----T-???---SEEE--EEE?SSEEEEEEEE------TTEEEEEEEE-??TT?----SEEEEEEEEEE?SSS?EEEEEE??EEE-EEE?HHHHHH?HHHHTTT?BE 3S4C|A PF06167.7_Peptidase_M90_seed 74 331 !Q:0,44|50,52|59,60|83,83|86,89|108,113|120,120|129,167|180,191|196,201|214,219|222,223|225,231|233,233|235,241|265,265|269,285|289,289|295,295|310,310|318,318 Q:45,49|53,58|61,82|84,85|90,107|114,119|121,128|168,179|192,195|202,213|220,221|224,224|232,232|234,234|242,264|266,268|286,288|290,294|296,309|311,317|319,330 ???------??---------------?????????????------HHHHT?--SGGGTT??HHHHHHHHHHHHHHHHHSEEEE?TT????HHHHHHHHHHHHGGGTTT?-----GGGGTT?SEEEEESS?????????-----???--?????????????????-??EEEEHHHHHHTT------------SSSS----??HHHHHHHHHHHH??????SS??S?-----?G-G-------GHHHHHHHHHHHHHHHHHHHHHH?TTT-----------------SSS?TTTTT?HHHHHHHHHHHHHH?GGGTTTT?HHHHHHHHHHHT 3DL1|A PF06169.7_DUF982_seed 51 81 !Q:7,7|10,10|12,12|15,15|30,31|33,38|56,56|58,58|75,80 Q:0,6|8,9|11,11|13,14|16,29|32,32|39,55|57,57|59,74 EEEEEEE?TT-S?EE-EEEEHHHHHHHHHH??S?-?--?SHHHHHHHHHHHHHHHT?S?HHHHHHHHHHHHHHHT?-???? 2KPQ|A PF06172.6_Cupin_5_seed 19 182 !Q:9,9|12,12|14,14|25,25|33,46|50,50|60,61|63,64|70,71|74,74|84,84|91,91|95,95|99,103|109,109|111,111|118,124|128,128|131,131|137,155|171,173|177,178|180,180 Q:0,8|10,11|13,13|15,24|26,32|47,49|51,59|62,62|65,69|72,73|75,83|85,90|92,94|96,98|104,108|110,110|112,117|125,127|129,130|132,136|156,170|174,176|179,179|181,181 HHHHHHHTT?EE?T-TSSEEEEEEE?SSBSSSS--------------SBS?EEEEEEEET--T??EEEEE?-SS?EEEEEEEES?EEEEEE?TTS?EEE-----EEESS?T-TTTEES------?EEE?TT?EEEEE-------------------ESSSSEEEEEEEESS???GGG??B?B 1YUD|A PF06175.6_MiaE_seed 6 250 !Q:0,4|12,14|26,27|53,103|106,106|136,144|155,155|188,189|219,219|245,246|249,249 Q:5,11|15,25|28,52|104,105|107,135|145,154|156,187|190,218|220,244|247,248 ?????HHHHSSS???HHHHHHHHTTH--HHHHHHHHHHHHHHHHHHHHHHHHT---------------------------------------------------TT?HHHHHHHHHHHHHHHHHHHHHHHHHHHTT?????????SHHHHHHTTS?SSTTHHHHHHHHHHHHHHHHHHHHHHHHGGGS-?HHHHHHHHHHHHHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHHSEESS??TT? 2ITB|A PF06178.8_KdgM_seed 7 236 !Q:0,8|17,24|34,34|48,63|71,71|75,75|96,97|100,101|125,139|154,156|166,166|171,183|194,196|210,223|235,235 Q:9,16|25,33|35,47|64,70|72,74|76,95|98,99|102,124|140,153|157,165|167,170|184,193|197,209|224,234 --------?EEEEEEEE????????EEEEEEEEE?TTSEEEEEEEEEE????????????????EEEEEEE-EEE?EESSSSEEEEEEEEEEEESS??EE??EEEEEEESSSSEEEEEEEEEEEE????????-??????EEEEEEEEEEEETT---TEEEEEEEE-EEEE?????????????EEEEEEEEEE??-SSSEEEEEEEEEE?????----????-EEEEEEEEEEE? 2WJR|A PF06179.7_Med22_seed 21 162 !Q:2,9|32,41|44,47|52,63|104,126|129,130|134,135|138,138|141,146|161,161 Q:0,1|10,31|42,43|48,51|64,103|127,128|131,133|136,137|139,140|147,160 HH--------HHHHHHHHHHHHHHHHHHHHHH----------HT????SSSS???------???SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT----------------???-???SS--TTS??SS?ST------HHHHHHHHHHHHHS? 4GWQ|D PF06180.6_CbiK_seed 8 302 !Q:7,9|11,11|30,30|40,41|45,46|55,72|85,86|93,94|97,97|109,117|128,129|132,134|138,144|160,165|175,177|195,195|198,198|200,200|211,211|224,225|227,231|237,237|241,242|266,267|269,269|272,281 Q:0,6|10,10|12,29|31,39|42,44|47,54|73,84|87,92|95,96|98,108|118,127|130,131|135,137|145,159|166,174|178,194|196,197|199,199|201,210|212,223|226,226|232,236|238,240|243,265|268,268|270,271|282,301 EEEEEEE???S?HHHHHHHHHHHHHHHHHT?TTSEEEEEE??HHH--HHHHHHHH?------------?????HHHHHHHHHHTT??EEEEEE??SB?SHHHHHHHHHH---------HHHGGGSSEE--EE???SBS-------SHHHHHHHHHHHHTT?????-TTEEEEEEE???SHHHHHHHHHHHHHHHH-HT?S-EEEEETTSSS?HHHHHHHHHHHT??E-----EEEEE?SSS??HHHHTTTTSSSTTSHHHHHHHTT??E-EE------????GGGSHHHHHHHHHHHHHHHH 2XVX|A PF06183.8_DinI_seed 11 69 !Q:0,1|20,20|24,25|35,35|42,43|47,48|67,68 Q:2,19|21,23|26,34|36,41|44,46|49,66 ??TTHHHHHHHHHHHHHHHH?SSS??EEEEEEESS?EEEEES??HHH--HHHHHHHHHHHHHTHHHH?? 1GHH|A PF06184.6_Potex_coat_seed 2 153 !Q:0,15|25,27|30,30|46,46|48,49|64,64|72,73|76,76|79,79|83,85|89,89|92,92|98,100|104,106|108,108|111,112|115,115|124,124|129,132|145,152 Q:16,24|28,29|31,45|47,47|50,63|65,71|74,75|77,78|80,82|86,88|90,91|93,97|101,103|107,107|109,110|113,114|116,123|125,128|133,144 ????????????????EEEEEEEEE???TT?EEEEEGGGSHHHHHS?S??EEEEEEEEEEEESS?EEEEEEE??TT?SS?SEE???EEE?SS?EEEEE???TTS???B?TT??TT?EEEEEEEE?SSTT????SEEEEEEEEEEE???????? 1STM|A PF06185.7_YecM_seed 6 195 !Q:2,2|28,30|33,33|42,42|44,44|95,97|99,99|101,102|105,105|114,115|117,117|121,123|133,138|147,147|152,165|171,175|178,178|186,186|194,195 Q:0,1|3,27|31,32|34,41|43,43|45,94|98,98|100,100|103,104|106,113|116,116|118,120|124,132|139,146|148,151|166,170|176,177|179,185|187,193 GG?GGGHHHHHHHHHHHHHHHHHHHHHT???TT?EEEEEEEE?S?HHHHHHHHHHHTTTEEEEEEEEETTEEEEEEEEEEEEEETTEEEEEEEEE???S-S??SS?EEEEEEEE??S?GGG---HHHHHHHTS-----?HHHHHSTT?EEEE??????????????EEEES-----SS?EEEEESS?HHHHHHH?- 1K4N|A PF06187.6_DUF993_seed 21 409 !Q:4,4|14,27|31,36|39,39|44,47|49,49|53,55|58,58|60,62|64,64|80,80|86,86|96,96|116,122|124,130|136,137|141,147|150,151|171,172|176,178|185,186|202,202|205,205|212,212|216,216|225,225|254,255|266,267|270,270|275,276|286,287|290,292|317,317|337,337|359,362|371,371|387,388|406,406|408,408 Q:0,3|5,13|28,30|37,38|40,43|48,48|50,52|56,57|59,59|63,63|65,79|81,85|87,95|97,115|123,123|131,135|138,140|148,149|152,170|173,175|179,184|187,201|203,204|206,211|213,215|217,224|226,253|256,265|268,269|271,274|277,285|288,289|293,316|318,336|338,358|363,370|372,386|389,405|407,407 EEEE-ETTEEEEEE????????--????GGG-----?SS?EEEE????B?TTS???TT-T???B?HHHHHHHHHHHHHTT?EEEET?GGGTBTTTB?HHHHHHHHHHHHHHHHTSS-------S??-----EEEEE??TTS?----??TT??HHHHHHHHHHHHHHHHHTT??EEE???HHHHHH??SHHHHHHHHHHHHHH?SS?EEEEEE?TTT?GGGTTTTS?SSHHHHHHHHHHHHHHTGGGEEEEEEES??HHHHHHHHTS??TT?EEEE??TTTHHHHHH??SS???EEEESHHHHTHHHHHHHHHHHHTT?HHHHHHHHTTHHHHHHHHT?SSGGGHHHHHHHHHHHTTSSS????GGGGGGSS?HHHHHHHHHHHHHTT??SSHHHHHHHHHHHHHHT-T? 4DNH|A PF06201.8_PITH_seed 56 248 !Q:0,1|15,21|24,27|29,29|39,59|61,63|66,74|76,77|83,84|88,88|98,122|126,127|129,129|137,138|141,143|149,149|152,153|156,156|159,177|179,184|191,192|195,200|204,204|215,226|230,233|236,237|239,240 Q:2,14|22,23|28,28|30,38|60,60|64,65|75,75|78,82|85,87|89,97|123,125|128,128|130,136|139,140|144,148|150,151|154,155|157,158|178,178|185,190|193,194|201,203|205,214|227,229|234,235|238,238|241,247 ??GGGEEEEEEEEES?-----?SS----S?SSTTSSSSS?-------------------?B??-SS-------?-S??EEEEE--EEE-EEEEEEEEE-?--??-------------------SSS??B?EEEEEES-?SS???TTHHH-HS??SS?EE-----------------??T------TTSSTT??EE----??TTT?TTEEEEEEEE----------??BTT--??SS??B??EEEEEEE 1WWY|A PF06204.6_CBM_X_seed 57 79 !Q:0,1|14,24|26,27|29,35|38,39|44,44|64,64|72,74|77,77 Q:2,13|25,25|28,28|36,37|40,43|45,63|65,71|75,76|78,78 ??SEEEETTTTEEE-----------E??S??-----SS??EEEE?SSSEEEEEETTSBEEEEES?TTTSEEE???TT?S 3S4C|A PF06205.6_GT36_AF_seed 111 102 !Q:1,1|6,8|11,12|18,18|22,26|28,29|41,41|44,45|49,49|53,56|61,66|70,70|82,82|85,85|98,99 Q:0,0|2,5|9,10|13,17|19,21|27,27|30,40|42,43|46,48|50,52|57,60|67,69|71,81|83,84|86,97|100,101 E?TTTT---TT??EEEEE-EES-----S??SEEEEEHHHHH?TT??TTS?HHH----HHTS??????BSS?EEEEEEEEEEE?TT?EEEEEEEEEEEE??GG 3S4C|A PF06214.6_SLAM_seed 4 128 !Q:0,32|34,34|42,42|50,51|53,60|70,70|74,76|83,83|86,87|89,90|93,94|111,112|116,116|125,125 Q:33,33|35,41|43,49|52,52|61,69|71,73|77,82|84,85|88,88|91,92|95,110|113,115|117,124|126,127 ?????????????????????????????????E-EEEETTS?EEEESSS?-S????????BEEEEEEES?STT???EEEEEE?TT??S??EE??SSEEEETTTTEEEETT??GGG?EEEEEEEE?SS 3ALW|A PF06220.7_zf-U1_seed 11 38 !Q:0,1|3,3|12,12|14,15|25,26 Q:2,2|4,11|13,13|16,24|27,37 ??S?EETTTTEE?S??SHHHHHHHT??THHHHHHHHHT 3CW1|0 PF06222.6_Phage_TAC_seed 6 141 !Q:0,2|16,16|20,20|35,37|48,63|71,75|90,90|94,97|101,101|112,113|127,130|132,140 Q:3,15|17,19|21,34|38,47|64,70|76,89|91,93|98,100|102,111|114,126|131,131 ???HHHHHHSSTTTTS?EEE-EEEGGGTTEEEEEE???HHHHHHHHHH??---?-??????-??HHHHHHH-----HHHHHHHHHHHHEE?TTS?---BSS?GGGHHHHHTT??HHHHHHHHHHHTT----T????????? 2OB9|A PF06227.7_Poxvirus_seed 37 273 !Q:0,115|120,120|123,123|125,126|144,146|152,154|173,176|178,178|181,185|192,196|198,198|200,202|215,216|218,221|223,224|243,246|250,251|265,266 Q:116,119|121,122|124,124|127,143|147,151|155,172|177,177|179,180|186,191|197,197|199,199|203,214|217,217|222,222|225,242|247,249|252,264|267,272 ?--------------------------------------------------------------------------------------------------------???????????TTSS?SS?S-?GGGHHHHHHHHHHHTTT---GGGTS???SHHHHHHHTHHHHHHHHH----S?HH-----HHHHHS?----T-T?--HHHHHHHHHHHS??S----S??HHHHHHHHHHHHHHHHHH?--?SSS??HHHHHHHHHHHHH??HHHHHH 2VVX|A PF06228.8_ChuX_HutX_seed 38 157 !Q:7,7|16,16|26,27|41,43|50,50|60,63|66,66|75,80|86,88|94,94|98,99|110,110|114,116|124,124|128,128|135,136|138,138|140,140|143,143|145,145 Q:0,6|8,15|17,25|28,40|44,49|51,59|64,65|67,74|81,85|89,93|95,97|100,109|111,113|117,123|125,127|129,134|137,137|139,139|141,142|144,144|146,156 HHHHTTS?HHHHHHTS?TTTEEEEEG--GGHHHHHHHHTTS??-EEEEEE?SSEEEEEEE????EE-EETTEEEE------EEETT---EEEEE?GGG??EEEEEEEEET-TEE---EEEEEEE?TTS?EEEEEE??B?T-TS?B?HHHHHHHHHHH 3FM2|A PF06229.7_FRG1_seed 13 237 !Q:1,1|6,6|10,10|14,17|22,25|29,29|35,36|40,40|49,49|54,56|64,65|68,69|77,87|89,89|93,94|99,112|116,116|121,121|125,127|131,132|134,136|140,141|146,146|148,236 Q:0,0|2,5|7,9|11,13|18,21|26,28|30,34|37,39|41,48|50,53|57,63|66,67|70,76|88,88|90,92|95,98|113,115|117,120|122,124|128,130|133,133|137,139|142,145|147,147 S?BEEE?TTS?EEE????SSSS????TTT?EEEEE?-SSS?EEEEETTS?BEEE?--SSSBEEE??SS??TTTBEEE-----------E?STT??EEEE--------------TTS?BEEE?SSS?--EEE??S???TTT??EEEE?S??-------?------------------------------------------------------------------------------- 2YUG|A PF06230.6_DUF1009_seed 83 253 !Q:12,13|21,26|28,28|31,39|52,52|55,55|58,58|73,73|76,76|80,80|90,92|99,102|125,125|139,139|143,143|151,168|173,173|178,183|187,189|194,199|202,206|209,209|221,222|231,231|248,248 Q:0,11|14,20|27,27|29,30|40,51|53,54|56,57|59,72|74,75|77,79|81,89|93,98|103,124|126,138|140,142|144,150|169,172|174,177|184,186|190,193|200,201|207,208|210,220|223,230|232,247|249,252 HHHHHHHHHHTT??EEEEESB?-????S-SS??-----??TTTTTTHHHHHH-HH-TT?HHHHHHHHHHHHHH-HT?EEE?HHHHHHTTB?-?SEESSS????HHHHHHHHHHHHHHHHHHHTTS?SEEEEETTEEEEE?SSS?HHHHHHH------------------HHTS?GGGS----??SSS???EEEE??????SS?????EE?HHHHHHHHHTT??EEEEESSS?EETTHHHHHHHHHHHT?EEEE 4J6E|A PF06234.7_TmoB_seed 10 99 !Q:0,2|12,12|15,15|21,21|24,24|37,47|54,59|72,73|76,76|79,79|85,87|90,90|98,98 Q:3,11|13,14|16,20|22,23|25,36|48,53|60,71|74,75|77,78|80,84|88,89|91,97 ???EEEEEEETT?SB?EEEEE?TT?BHHHHHHHHHTT-----------TBTTTB??---?TTSEEEEEETTT??EE?TT?BGGGS???TT?EEEEEEE? 3N20|C PF06236.6_MelC1_seed 9 147 !Q:0,51|66,89|101,101|105,105|109,109|136,136|138,139|141,147 Q:52,65|90,100|102,104|106,108|110,135|137,137|140,140 ????????-??????????????????????----------------?????EEEEETTEEEEEEE????????------------????SEEEEETTEEE?EEE?TTS?EEETTEEEEEESSHHHHHHHHHHHHT-T??B??????- 2ZMY|B PF06240.8_COXG_seed 15 147 !Q:7,7|17,17|36,36|55,58|75,77|84,84|122,122|147,147 Q:0,6|8,16|18,35|37,54|59,74|78,83|85,121|123,146 EEEEESS?HHHHHHHHT?HHHHGGGSTTEEEEEEET-TEEEEEEEEESSSSEEEE----EEEEEEEEEETTTEEE---EEEEEE?SSEEEEEEEEEEEEEETTEEEEEEEEEEEEEEGGGGS?HHHHHHHHHHHHHHHHHHHHHHHT- 2NS9|A PF06243.6_PaaB_seed 43 223 !Q:0,3|11,11|14,14|17,17|25,25|43,43|46,46|56,136|139,222 Q:4,10|12,13|15,16|18,24|26,42|44,45|47,55|137,138 ????EEEEEEE?TT?SS?EEEEEEE?SSHHHHHHHHHHHTTTT?TT?EEEEEEGGG?--------------------------------------------------------------------------------EE?????--------------???????????????????-----???--------------------------??------???? 3EGR|A PF06246.7_Isy1_seed 31 371 !Q:0,23|26,34|36,36|40,42|67,68|70,70|97,97|102,103|110,155|157,370 Q:24,25|35,35|37,39|43,66|69,69|71,96|98,101|104,109|156,156 -------------------?????SS??----???S?TTT???HHHHHHHHHHHHHHHHHHHHHHHH??S?HHHHHHHHHHHHHHHHHHHHHHHHHH-HHTS??STTTSS----------------------------------------------S-----------------------------------------???-------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1X4T|A PF06247.6_Plasmod_Pvs28_seed 11 256 !Q:0,2|5,7|15,15|18,18|24,24|38,42|45,45|61,61|68,68|75,75|93,96|117,117|135,143|161,161|164,164|171,231|237,255 Q:3,4|8,14|16,17|19,23|25,37|43,44|46,60|62,67|69,74|76,92|97,116|118,134|144,160|162,163|165,170|232,236 ???TT???BTEEEEE?SS?EEEEE?TTEEEEETTEEEE??-??SG-GGTTSEEETTEEEEE?SSTTSS?SEEEEE?TTEEEETTEEEEGGGTT????TTEEEEEEEETTEEEEEEEE?TEEEEETTTTTEEEEEE?????????TTTEEEEEETTEEEEEE?TT?EEETTT-------------------------------------------------------------TEEES-----------------?? 1Z1Y|A PF06249.7_EutQ_seed 4 152 !Q:0,25|29,29|33,33|37,37|41,41|45,48|53,55|57,57|60,61|67,67|69,69|73,73|76,76|92,92|120,120|125,125|128,128|146,146|148,151 Q:26,28|30,32|34,36|38,40|42,44|49,52|56,56|58,59|62,66|68,68|70,72|74,75|77,91|93,119|121,124|126,127|129,145|147,147 ---------?????????????--??SSS?EEE?TTS?EEE?GGG????GGGB???S?TT??EEEEE?S?TTT?SS?EEEEEEEEEEEEEEE?SSEEEEEEEEEEEEEEETTEEEEEETT?EEEE?TT?EEEEEEEEEEEEEEEEE?S???? 1O5U|A PF06251.6_Caps_synth_GfcC_seed 17 262 !Q:0,2|9,9|13,15|17,17|33,33|36,47|53,53|57,57|61,61|85,89|92,92|109,120|124,124|132,132|134,136|143,147|157,158|160,166|168,168|173,174|177,178|187,187|189,189|193,193|201,201|205,205|211,211|216,218|221,222|225,225|230,230|232,234|239,239|244,245|258,259 Q:3,8|10,12|16,16|18,32|34,35|48,52|54,56|58,60|62,84|90,91|93,108|121,123|125,131|133,133|137,142|148,156|159,159|167,167|169,172|175,176|179,186|188,188|190,192|194,200|202,204|206,210|212,215|219,220|223,224|226,229|231,231|235,238|240,243|246,257|260,261 ???EEEEEE?TTS---S?EEEEEEESBHHHHHT?TT------------TTTTS?GGG?EEE?HHHHHHHHHHHHHHHHHHHHHHH-----HS?HHHHHHHHHHHHHHTT????????????TTS?EESGGGS?B?-?EEEEEE?????SEEEEEESB--T-------T?EEEE??TT??HHHHHTTS?B?TTB?SSEEEEE?TTS?EEEEE?SSTT???EE??TT?EEEE?B--?TTTS?GGGT--THHHHHHHHHHT??GG 3P42|A PF06253.6_MTTB_seed 8 517 !Q:0,34|36,36|55,55|59,60|63,63|73,73|76,77|84,85|97,97|99,99|103,104|110,110|117,118|123,124|126,127|131,131|135,135|137,137|140,141|155,155|158,158|164,164|167,168|172,172|175,175|189,189|195,197|199,199|216,217|225,228|234,234|241,241|256,256|263,264|271,271|299,300|306,307|311,311|315,315|319,319|341,341|345,346|348,351|374,374|391,391|411,414|420,420|428,431|434,435|450,453|456,460|468,471|487,493|502,505 Q:35,35|37,54|56,58|61,62|64,72|74,75|78,83|86,96|98,98|100,102|105,109|111,116|119,122|125,125|128,130|132,134|136,136|138,139|142,154|156,157|159,163|165,166|169,171|173,174|176,188|190,194|198,198|200,215|218,224|229,233|235,240|242,255|257,262|265,270|272,298|301,305|308,310|312,314|316,318|320,340|342,344|347,347|352,373|375,390|392,410|415,419|421,427|432,433|436,449|454,455|461,467|472,486|494,501|506,516 ???????????------?????????---??????S?HHHHHHHHHHHHHHHHHT?EEE??HH-HHHHHHHTT?EE--ETTEEE??HHHHHHHHTTS?S?EEE??SSGGG?EEESSS??EEEE??S??EEE?TTS?E-EE??HHHHHHHHHHHHH?TT?SEEES?SS??TTS?TT-THHHHHHHHHHHH?SSEEB???S?HHHHHHHHHHHHHHHS?-HHHHHHS?-??EEEEE?BTTTEE?HHHHHHHHHHHHTT?EEEEEE??EETTTB?SSHHHHHHHHHHHHHHHHHHHHHHSTT??EEEEE??EEE?TTT?SEE?SSHHHHHHHHHHHHHHHHHTS?EEE??S????SSSSHHHHHHHHHHHHHHHHTT?SEEEEEESEEGGGTEE?HHHHHHHHHHHHHHHHHHH????SHHHH?HHHHHHH---?TT??STTSHHHHHHHHHH????SS?????HHHHTTT-???HHHHHHHHHHHHHHH???????HHHHHHHH----HHHHHHHHHHT 2QNE|A PF06254.6_DUF1019_seed 12 106 !Q:4,11|22,22|27,30|50,53|65,65|69,75|86,94 Q:0,3|12,21|23,26|31,49|54,64|66,68|76,85|95,105 SSTT--------HHHHHHHHHH-HHHH?--?SHHHHHHHHHHHHHHHHHS---?HHHHHHHTTSS?HHH-------HHHHHHHHHH---------HHHHHHHHHHH 3C4R|A PF06257.6_DUF1021_seed 44 84 !Q:24,25|29,30|32,32|41,41|49,50|53,55|60,61|64,64 Q:0,23|26,28|31,31|33,40|42,48|51,52|56,59|62,63|65,83 HHHHHHHHHHHHHHTTTSEEEEEE??SSS??S?EEEEEEEE?SSEEEEE--ES?--STTS??SS?EEEEEEHHHHHTTSEEEEE 3FB9|A PF06262.6_DUF1025_seed 78 112 !Q:11,16|21,29|35,37|43,43|47,48|50,53|67,73|79,80|99,100|107,108|111,111 Q:0,10|17,20|30,34|38,42|44,46|49,49|54,66|74,78|81,98|101,106|109,110 GTTEEEEEESS--?---SSTT--------?SEEEE???GGGSB?TTS-?B??--EEEEEEHHHHHHT?------SSHHH--HHHHHHHHHHHHHHHHTT??HHHHHT--TT? 3E11|A PF06265.6_DUF1027_seed 32 86 !Q:16,18|26,27|40,40|45,45|50,53|55,55|58,58|60,60|63,64|76,76|79,80 Q:0,15|19,25|28,39|41,44|46,49|54,54|56,57|59,59|61,62|65,75|77,78|81,85 EEETTEEEEEEEEETT???HHHHHHH??GGGGGTSEEEEE?TTSS?EEEE????S?TT?S?TT??TTHHHHHHHSS?SS??EEEEE 2KL5|A PF06267.7_DUF1028_seed 78 254 !Q:23,23|25,28|32,32|48,48|51,52|67,69|81,83|89,89|99,103|109,109|113,113|116,119|127,128|136,136|138,138|152,172|174,176|192,205|214,218|222,231|239,241|244,245|247,249 Q:0,22|24,24|29,31|33,47|49,50|53,66|70,80|84,88|90,98|104,108|110,112|114,115|120,126|129,135|137,137|139,151|173,173|177,191|206,213|219,221|232,238|242,243|246,246|250,253 EEEEEEEETTTTEEEEEEEESSS?H----HHH-HEEEETTTEEEEEES-SS??HHHHHHHHHHHHTT-??HHHHHHHHHHT?--TTGGG?EEEEEETTS----?EEEEE?TTS?SS---?EEEEETT--EEEEEES?S?THHHHHHHHHHHH??-------------------S--?HHHHHHHHHHHHHHT?????----?--??EEEEEEEE-----TTE----------EEEEEEE???SS-?H---HHHH 2IMH|A PF06268.8_Fascin_seed 23 134 !Q:14,18|24,25|30,31|36,36|45,47|51,52|55,56|60,60|63,65|69,69|74,80|84,84|91,94|102,102|106,106|120,126|130,130 Q:0,13|19,23|26,29|32,35|37,44|48,50|53,54|57,59|61,62|66,68|70,73|81,83|85,90|95,101|103,105|107,119|127,129|131,133 EEEEETTTTEEEEE?????SSEEE--EESS??SGGG?EEEEEETT---EEE--EE-?TTS?EE?--TTS?EESS??-----GGG?BEEEEE----TTEEEEE?TTS?BEEEETTTTEEEE???????GGG?EEE 3O4D|A PF06276.7_FhuF_seed 156 228 !Q:19,20|24,24|27,36|46,46|49,49|55,56|60,62|66,66|70,70|72,75|77,80|82,92|97,97|100,103|105,105|131,136|138,138|142,142|168,174|179,179|182,182|186,189|194,217|220,227 Q:0,18|21,23|25,26|37,45|47,48|50,54|57,59|63,65|67,69|71,71|76,76|81,81|93,96|98,99|104,104|106,130|137,137|139,141|143,167|175,178|180,181|183,185|190,193|218,219 HHHHHHHHHHHHHHHHHHH--HHH?EE?-------??STTTEEEEE-ET-TEEEE--EEE???TTT?EES?T----T????T-----------TSGG-GB????G-GGSSHHHHIIIIITTHHHHHHHHHH------T-TSS?HHHHHHHHHHHHHHHHHHSGGGHHH-------HHHT?TT?SEE????HHHH------------------------HH???????? 2W03|A PF06280.7_DUF1034_seed 47 174 !Q:6,7|10,11|21,21|25,25|34,38|44,48|50,51|63,84|88,90|96,96|109,110|116,128|137,137|153,167 Q:0,5|8,9|12,20|22,24|26,33|39,43|49,49|52,62|85,87|91,95|97,108|111,115|129,136|138,152|168,173 EEEEEE-?SE--EEEEEEEEE?SSS?EEEEEEEE-----EEEEE-----E--ETTEEEEEEEE----------------------EEE???EEEEE?TTEEEEEEEEEE?-GGGHH-------------HHHHHSTT?EEEEEEEEEESSTTS-?-----------??EEEEEE 1XF1|A PF06283.6_ThuA_seed 91 548 !Q:6,8|13,13|15,16|22,22|24,34|36,36|48,50|53,53|63,63|68,69|71,75|78,87|91,91|98,98|101,101|106,119|121,121|133,133|136,137|151,173|177,177|180,180|182,327|332,342|351,352|355,355|364,369|372,392|404,406|408,410|412,414|423,451|455,455|466,495|504,513|515,524|527,527|530,530|532,532|547,547 Q:0,5|9,12|14,14|17,21|23,23|35,35|37,47|51,52|54,62|64,67|70,70|76,77|88,90|92,97|99,100|102,105|120,120|122,132|134,135|138,150|174,176|178,179|181,181|328,331|343,350|353,354|356,363|370,371|393,403|407,407|411,411|415,422|452,454|456,465|496,503|514,514|525,526|528,529|531,531|533,546 EEEEEE???HHHH?H--HHHHH?T-----------T?HHHHHHHHHHH---TT?EEEEEESSS-GGGG??H-----HH----------HHT?SEEEEE?SS?GGGS-------------?H-HHHHHHHHHHH-TT-?EEEEEGGGGGSHH-----------------------HHH-HH?S----------------------------------------------------------------------------------------------------------------------------------------------????EEEE-----------EEEEEEEE--ES?TTSGGGTT?---?-SE---------------------EEEEEEEEEES???S???S---EEEEEEEE-----------------------------TTS?EEEEEEEEEE------------------------------TTEEEEEE????------T----------TS?GG-G?HHHHHHHHHHHHHH? 1T0B|A PF06288.8_DUF1040_seed 15 87 !Q:0,2|18,18|24,24|38,38|41,41|45,46|65,65|68,75|84,84 Q:3,17|19,23|25,37|39,40|42,44|47,64|66,67|76,83|85,86 ???HHHHHHHHHTHHHHH-SSTTS?HHHHHHHHHHHTT?SS?TTS??HHHHHHHHHHHHHTTSSS?SS????????HHHHHHHH?SS 2KO6|A PF06290.6_PsiB_seed 5 144 !Q:0,6|12,13|24,24|39,42|50,50|56,56|58,58|70,71|79,79|84,84|97,97|108,109|128,129|143,143 Q:7,11|14,23|25,38|43,49|51,55|57,57|59,69|72,78|80,83|85,96|98,107|110,127|130,142 ???????HHHHH??HHHHHHHHHH?HHHHHHHHHHHHHT????TTEEEEE?SSSTT?S?SSSEEEEEETT-?SEEEEEE?SSSS?SSEEEEEEEGGG?SEEEEEEESS??HHHHHHHHHHHHHHHHTT??HHHHHHHHHHHHT? 3NCT|A PF06293.9_Kdo_seed 14 226 !Q:7,7|17,17|30,30|38,52|55,55|73,74|79,80|93,110|116,124|126,126|148,148|151,151|163,170|174,176|179,179|184,185|197,197|201,209|213,217 Q:0,6|8,16|18,29|31,37|53,54|56,72|75,78|81,92|111,115|125,125|127,147|149,150|152,162|171,173|177,178|180,183|186,196|198,200|210,212|218,225 HHHHTTS?SEEEEEEEE?EEEEEEEETTTE-EEEEEEE????????????-??HH-HHHHHHHHHHHHHHHTT--TSSS??EEEEETTEEEEE--------------????EEGGG------???S?HHHHHHHHHHHHHHHHHTTEE?SS?STTTEEEETTE--------EEE???TT?EETT--STTHHHHHHHH-HHH---------HHH?????HHHHHHHH 1YXS|A PF06294.6_DUF1042_seed 6 164 !Q:7,9|11,12|14,15|18,18|37,37|41,43|46,49|72,75|86,86|108,163 Q:0,6|10,10|13,13|16,17|19,36|38,40|44,45|50,71|76,85|87,107 HHHHHHH---S??S??SS?HHHHHTTSHHHHHHHHHH?TTT???SS????SSHHHHHHHHHHHHHHTTGGGT????HHHHHHHHTT?TTTTHHHHHHHHHHHHHHHHS???----------------------------------------------------- 2EE7|A PF06298.6_PsbY_seed 22 37 !Q:0,1|33,34|36,36 Q:2,32|35,35 -?HHHHHHHHHHHHHHHHHHHTTHHHHHHHHHH--H? 4IL6|R PF06303.7_MatP_seed 13 148 !Q:0,5|25,27|30,30|49,49|62,62|89,90|92,93|111,113|146,147 Q:6,24|28,29|31,48|50,61|63,88|91,91|94,110|114,145 ??????HHHHHHHHHHHHHHHHTTT???BS?SSHHHHHHHHHHHHTTSS?SHHHHHHHHHHB?HHHHHHHHHHHHHHHHHHHHTTSGGG??B??EEEHHHHHHHHHHHHHH???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?? 3VEB|A PF06304.6_DUF1048_seed 16 105 !Q:20,20|41,41|65,66|72,72|74,74|87,87|89,90 Q:0,19|21,40|42,64|67,71|73,73|75,86|88,88|91,104 HHHHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHSSTTSB?SHHHHHHHHHHHHHHHHHHHHTT??HHHHH?S?HHHHHHHHHTTS?B--HHHHHHHHHHHHHT 2O4T|A PF06314.6_ADC_seed 72 355 !Q:4,4|7,11|14,17|22,26|37,38|46,47|49,49|51,51|54,54|56,62|77,77|81,90|103,103|106,121|124,127|129,129|140,143|155,157|161,161|168,180|182,182|193,193|207,207|210,211|222,233|242,243|247,247|251,253|261,261|269,274|279,281|287,291|294,295|298,307|310,312|327,332|334,336|342,354 Q:0,3|5,6|12,13|18,21|27,36|39,45|48,48|50,50|52,53|55,55|63,76|78,80|91,102|104,105|122,123|128,128|130,139|144,154|158,160|162,167|181,181|183,192|194,206|208,209|212,221|234,241|244,246|248,250|254,260|262,268|275,278|282,286|292,293|296,297|308,309|313,326|333,333|337,341 SSST-TS?----SS????EEEE-----EEEEEEEEEE??HHHHHTT??T-T?EE?S-------SEEEEEEEEEEEET-TTE----------EEEEEEEEEEEE-ET----------------TE----E-EEEEEEEEES---?HHHHHHHHHHT???EEE?EEEEEE-------------E-TTEEEEEEEE-TTEEEEEEEEESS?EE??HHHHHHHTTS-----------?EEEEEEEE?-TTS-SEE---EEEEEEE?EEEEEEE------EEEE??-EEEEE-???-SS??GG----------GS??-SEEEEEEEEEEEEE------E???EEEEE?-----------? 3CMB|A PF06315.6_AceK_seed 39 656 !Q:30,30|60,62|69,83|101,101|122,125|130,130|133,133|136,147|150,150|156,157|159,163|165,165|177,180|185,185|202,202|205,212|217,217|225,225|241,242|246,247|249,250|256,261|266,266|270,272|277,279|281,282|291,291|295,297|299,301|318,319|329,329|346,346|349,354|358,358|361,363|371,371|374,374|382,382|385,386|389,392|394,397|411,412|417,419|433,433|450,452|457,460|472,473|483,484|487,495|497,500|508,511|526,526|528,530|537,537|540,541|545,546|550,550|556,556|559,560|563,588|590,592|597,600|604,604|611,611|623,623|628,628|643,648|651,651 Q:0,29|31,59|63,68|84,100|102,121|126,129|131,132|134,135|148,149|151,155|158,158|164,164|166,176|181,184|186,201|203,204|213,216|218,224|226,240|243,245|248,248|251,255|262,265|267,269|273,276|280,280|283,290|292,294|298,298|302,317|320,328|330,345|347,348|355,357|359,360|364,370|372,373|375,381|383,384|387,388|393,393|398,410|413,416|420,432|434,449|453,456|461,471|474,482|485,486|496,496|501,507|512,525|527,527|531,536|538,539|542,544|547,549|551,555|557,558|561,562|589,589|593,596|601,603|605,610|612,622|624,627|629,642|649,650|652,655 HHHHHHHHHHHHHHHHHHHHTTHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHT---TSTTTT?--------------HHHHHHHHHHHHTTTTT?TTHHHHHHHHHHHHHHHTTT????TTTS?SS?SS?----???????SS?SEEEE??S-----S?SSSHHHHHHTT????SEES?HHHHHHHHHHHHHHHH?HH--------HHTT?EEEEESS?EEETTEEEEEEEEEE--TTE--E--EEEEE------EEEE?TTS---EEEE???B??HHHHHHHT?TTS???B???SSHHHHHHHHHHSSTT??HHHHHHHHT?HHHHHHHHHHHHHHHH-HT?--???BEE?SS???SSEEEEE?TT?SEEEEEE?SS??TT????H----HHHHHHHHHHHTS??TTTB???EEEEEEEEEGGGB?HHHHHHHHHHSGGGEE---EETT----EEEEEEEEEEE??EEHHHHHHH??TH---------H----HHHHHHH----HHHHHHHHHHTTEE?S???GGGEEE?TT??EEE??GGG?EESTT?EE-?SS?????????-----------??????S???TTEE--?-TTH-HHHHHT?STTTHHHHHHH?GGGG?HHHHHHHHHHHHTT??????SS?GGGS 3EPS|A PF06316.6_Ail_Lom_seed 2 199 !Q:0,27|35,36|44,45|57,58|62,62|71,78|82,84|88,92|123,130|132,139|141,142|144,152|166,167|171,171|198,198 Q:28,34|37,43|46,56|59,61|63,70|79,81|85,87|93,122|131,131|140,140|143,143|153,165|168,170|172,197 --------------------------??EEEEEEE--EEEEEET??EEEEEEEEEEE??SSS?EEEEEEEE--------EEE???SSS?????EEEEEEEEEEEEEETTTEEEEEEEEEEEEE--------E????????S??S---------SEEEEEEEEEEEE??STT?EEEEEEEEEEETTEEEEEEEEEEEEE? 2M06|A PF06319.7_DUF1052_seed 7 158 !Q:0,12|16,21|36,36|43,43|48,49|56,56|59,60|67,67|86,86|94,94|98,98|103,103|112,112|115,115|121,128|152,152|157,157 Q:13,15|22,35|37,42|44,47|50,55|57,58|61,66|68,85|87,93|95,97|99,102|104,111|113,114|116,120|129,151|153,156 ??????-----??HHH------HHHHHHHHHHHHTT?EEEEEE?SSTT??EEEEEE?TT??EEEEEE?SSHHHHHHTTTGGGGGGG?SEEEEEE?TTS?GGGS?TTSEEEEE?SS?EEEEE????????HHHHHHHHHHHHHHHHHHHHHHH?TTSS? 3DNX|A PF06321.6_P_gingi_FimA_seed 32 558 !Q:0,24|26,29|37,41|43,61|64,66|75,76|80,80|88,88|91,91|102,127|131,134|137,137|147,171|176,181|183,183|188,188|193,195|199,200|202,202|209,211|214,218|220,222|225,227|231,232|235,235|240,256|262,262|271,290|296,309|314,314|319,320|324,324|332,343|347,349|352,352|359,370|382,392|394,394|399,400|402,453|457,459|461,463|469,470|478,505|507,514|517,518|520,523|528,528|530,532|535,541|548,554 Q:25,25|30,36|42,42|62,63|67,74|77,79|81,87|89,90|92,101|128,130|135,136|138,146|172,175|182,182|184,187|189,192|196,198|201,201|203,208|212,213|219,219|223,224|228,230|233,234|236,239|257,261|263,270|291,295|310,313|315,318|321,323|325,331|344,346|350,351|353,358|371,381|393,393|395,398|401,401|454,456|460,460|464,468|471,477|506,506|515,516|519,519|524,527|529,529|533,534|542,547|555,557 ----???????????????------E----EEEEEEE-----E??????????????----?TT???EEEEEEEE--TTS?EEEEEEE?EE?TTSEEEEEEE--------------------------EEE----SE-EEEEEEEES-----------------------??HHHH------H-HHHT?SSHH---HHH--T?EEEGGG?-?TT-----T???EE???EEE--EE?TTSE-----------------EEESS?SSSEEEEE--------------------TTEEE--------------EESS?SSSB??EES?EEEEEEE------------EEE???SS?SEEEEE------------EEEEEEEEESE-----------E?EEES??S----------------------------------------------------STT???B???STTSS??GGGEEES??-----------------------???S--------SS??S?---BTTB?S-??EE------?GGGEEE------?BTT 3LIU|A PF06325.8_PrmA_seed 31 491 !Q:0,4|9,9|16,19|25,28|31,31|33,36|38,70|73,74|76,91|93,93|95,113|118,118|121,127|130,134|136,163|165,169|171,197|200,204|206,213|220,222|228,228|233,233|236,248|256,259|263,264|266,266|281,295|298,304|307,308|310,310|314,314|328,329|337,337|352,357|359,363|366,374|376,378|384,384|387,389|392,399|401,411|413,415|423,423|458,458|460,460|462,462|465,465|469,469|471,471|487,490 Q:5,8|10,15|20,24|29,30|32,32|37,37|71,72|75,75|92,92|94,94|114,117|119,120|128,129|135,135|164,164|170,170|198,199|205,205|214,219|223,227|229,232|234,235|249,255|260,262|265,265|267,280|296,297|305,306|309,309|311,313|315,327|330,336|338,351|358,358|364,365|375,375|379,383|385,386|390,391|400,400|412,412|416,422|424,457|459,459|461,461|463,464|466,468|470,470|472,486 -----EEES?TTTTGG----GHHHH----HH-H----T-?------------------------------?EE--E----------------E?S-------------------SEEE-EE-------ES-----S-???---------------?--------T-----T?------?-------------------EE-----E????????HHHHHS???EEETT-EEEE?TT-???----?----SSSEEEE????SSS??S?SHHHHHHHHHHHHH-------------??TT--?----EE--E-EES?TTSHHHHHHHHTT-?EEEEEES?GGGHHHHHHHHHHH------T???--EE---------E---ESSHH-HH---GG--------G---------??E---EEEEEES?HHHHHHHHHHHHHHEEEEEEEEEEEEEGGGHHHH-H-H-HH-HHT-T?EEEEEEEETTEEEEE---- 1VQ1|A PF06326.7_Vesiculo_matrix_seed 11 247 !Q:0,58|65,67|71,78|96,97|114,115|117,117|135,135|138,138|144,144|148,148|163,163|165,171|173,174|183,183|186,186|199,200|202,206|213,218|238,238|244,244|247,247 Q:59,64|68,70|79,95|98,113|116,116|118,134|136,137|139,143|145,147|149,162|164,164|172,172|175,182|184,185|187,198|201,201|207,212|219,237|239,243|245,246 --??????????????????????-----------???????????------???????TTTSTT?--TTT????????EEEEEEEEEEEEEEESS??SSHHHHHHHHGGGGSS??S?GGGHHHHHHHHHHHHTT?EE?THHHH?TTS?EEEEEEEEEEEEEE?S???????S??EEEEEEEE?SS?EEEEEEEEEEEE??S?????BGGGGS-----?GGGGGGHHHHHHHTTEEEE?SSSSS?EE- 2W2R|A PF06328.6_Lep_receptor_Ig_seed 12 103 !Q:0,3|12,14|18,19|21,22|27,29|37,39|43,43|50,54|58,58|61,61|66,67|70,71|75,77|79,89|93,94|99,101 Q:4,11|15,17|20,20|23,26|30,36|40,42|44,49|55,57|59,60|62,65|68,69|72,74|78,78|90,92|95,98|102,102 ????SEEEESSS???BTT??B??EEEE?--HHHHHHS???TTS?EEESSS?-???TTS?EE?STTE--EE??BSS???S??-------??EEE??TTTT???E 1P9M|A PF06330.6_TRI5_seed 3 379 !Q:0,1|3,4|21,24|26,27|56,59|78,78|82,82|102,104|106,106|122,124|144,144|168,172|175,175|188,188|197,198|202,203|237,237|240,243|254,255|282,282|303,303|307,307|318,320|338,340|346,346|348,348|355,378 Q:2,2|5,20|25,25|28,55|60,77|79,81|83,101|105,105|107,121|125,143|145,167|173,174|176,187|189,196|199,201|204,236|238,239|244,253|256,281|283,302|304,306|308,317|321,337|341,345|347,347|349,354 ??S??HHHHHHHHHHHHHHTT????S??HHHHHHHHHHHHHHHHHHHTSHHHHHHS?-??HHHHHHHHHHHHHHHHHH?TTS?HHHHHHHHHHHHHHHHGGG?-?S?SHHHHTTHHHHHHHT???SSHHHHHHHHHHHHHHTTS?HHHHHHHHHHHHHHHHHHHHHTT?????TT?TTHHHHHHHHHH?HHHHHHTT??TTT??TTTTHHHHHHHHHHHHHHHHHHHHHHTHHHHTT?SS????HHHHHHHHHT??HHHHHHHHHHHHHHHHHHHHHHHTTS?HHHHHHHHHHHHHHHHHHHH?GGG?THHHHHHHSS???HHHHHHHHHHHHHHHHH???GGGTS?S?HHHHHH???---???????-?????????? 2PS5|A PF06331.7_Tbf5_seed 30 77 !Q:0,1|7,7|13,13|32,35|42,42|49,52|69,74|76,76 Q:2,6|8,12|14,31|36,41|43,48|53,68|75,75 ??EEEEE-EEEES?THHHHHHHHHHHHTTTSS--??EEEEET-TTEEEE?---GGGHHHHHHHHHHTTT??????S? 2JNJ|A PF06335.7_DUF1054_seed 22 202 !Q:0,1|11,11|45,45|47,48|53,55|59,59|62,63|65,65|73,73|76,76|81,81|88,88|99,99|102,102|104,105|126,126|129,129|134,134|138,140|146,147|161,161|164,165|180,180|182,182 Q:2,10|12,44|46,46|49,52|56,58|60,61|64,64|66,72|74,75|77,80|82,87|89,98|100,101|103,103|106,125|127,128|130,133|135,137|141,145|148,160|162,163|166,179|181,181|183,201 ??HHHHGGGGS?SHHHHHHHHTTTHHHHHHHHHHHHHHHHHHHHS-S??EEEE???TTT?SS??S?EEEEEES?SS?STTS?EEEEEE?SSEEEEEEEE?TT?T--THHHHHHHHHHTHHHHHHHS?TT?EEES?TTS???EEGGG??HHHHHHHHHHHHH?TT??EEEEEEEEHHHHHH-S?HHHHHHHHHHHHHHHHHHH 2A8E|A PF06337.7_DUSP_seed 139 273 !Q:1,1|9,9|11,19|32,34|36,37|43,43|45,150|153,166|169,178|189,214|217,218|220,221|223,224|229,229|234,242|245,245|255,255|257,258|260,260|263,266 Q:0,0|2,8|10,10|20,31|35,35|38,42|44,44|151,152|167,168|179,188|215,216|219,219|222,222|225,228|230,233|243,244|246,254|256,256|259,259|261,262|267,272 T?EEEEEEH-H---------HHHHHHHHHTSS---S??TTTTT?G----------------------------------------------------------------------------------------------------------GG???-----------SB---?-----?GGGEEETTTT--------------------------EE?-S--S??BTTT-EEEE---------EH-HHHHHHHHH-H-?B?TT????EEEEEE 4A3O|A PF06340.6_TcpF_seed 5 339 !Q:0,34|47,48|55,55|60,62|73,83|85,85|97,97|110,111|114,114|116,116|119,121|136,136|138,138|156,156|167,169|173,173|176,179|186,189|191,191|197,198|200,212|216,216|218,219|223,224|240,246|250,250|258,260|264,266|269,269|276,285|294,296|300,300|310,310|313,313|321,321|325,325|328,328|331,333|335,335 Q:35,46|49,54|56,59|63,72|84,84|86,96|98,109|112,113|115,115|117,118|122,135|137,137|139,155|157,166|170,172|174,175|180,185|190,190|192,196|199,199|213,215|217,217|220,222|225,239|247,249|251,257|261,263|267,268|270,275|286,293|297,299|301,309|311,312|314,320|322,324|326,327|329,330|334,334|336,338 ??????????????????-------???????--?TTTTHHHHHHTT??GGGGGG-GGTB???TTSSGGGGGS????-??????S?HHHHHHHHHTT?HHHHHHHTGGGT??TT?S?EE???HHHHHHHHHHHHTT?S?HHHHHHTSSEEEEEEET-TEEEEEEESS?-?TTS?EE????EETTTS????S?SSEEE??B?????-----???TTS?B??TTS??EEEEEEEHHHHHTTT???----TTS?EEEEEEE???TTT???SS?SEEEEE??????????SEEEEEEE???SSS?STTHHHHTT?TT?EEEEEEE?TTS?SS?EE???B?GGG 3OC8|A PF06345.6_Drf_DAD_seed 3 15 !Q:0,0 Q:1,14 ?HHHHHHHHHHHSTT 2F31|B PF06347.8_SH3_4_seed 29 58 !Q:0,0|15,15|18,18|25,25|31,31|42,42|51,51 Q:1,14|16,17|19,24|26,30|32,41|43,50|52,57 ?SSEEEEESSSSTTT?EE-EEEETT?EEEEE-EEETTEEEEE-ETTEEEEE?SSSEEE 2KRS|A PF06351.6_Allene_ox_cyc_seed 10 186 !Q:0,7|16,17|19,19|21,25|27,27|30,31|33,33|37,38|40,42|45,45|50,51|59,60|91,91|95,95|107,107|109,109|124,124|149,153|157,157|159,164|167,170|177,177|182,182|185,185 Q:8,15|18,18|20,20|26,26|28,29|32,32|34,36|39,39|43,44|46,49|52,58|61,90|92,94|96,106|108,108|110,123|125,148|154,156|158,158|165,166|171,176|178,181|183,184 ????????EEEEEEEE??S?S?????B?TT??B?TTT??B???TT?EEEE??EEEETTS??EEEEEEEEEEEEEEETTTTEEEEEEEEEEE?GGG?EEEEEEEEETT-B?EEEEEEEESGGGTT?EEEEEEEEEETTTEEEEEEEEESS?-???GGG?S??????TT????HHHHTT?TTSB?TT? 4H69|A PF06357.6_Omega-toxin_seed 2 37 !Q:0,2|5,5|10,10|20,20|26,26|30,30|36,36 Q:3,4|6,9|11,19|21,25|27,29|31,35 ???SB?TTSB?SSGGGBSSS?EEEEE?SSS?EEEEE? 1AXH|A PF06360.6_E_raikovi_mat_seed 6 39 !Q:0,0|10,10|19,20|37,38 Q:1,9|11,18|21,36 ?HHHHHHHTT?HHHHHHTS?-TTHHHHHHHHHTSTTT?? 1ERD|A PF06367.11_Drf_FH3_seed 37 276 !Q:18,19|21,21|24,24|33,52|56,56|74,89|115,121|144,153|158,165|171,173|182,184|198,198|209,218|239,239|244,246|248,253|255,257|260,275 Q:0,17|20,20|22,23|25,32|53,55|57,73|90,114|122,143|154,157|166,170|174,181|185,197|199,208|219,238|240,243|247,247|254,254|258,259 THHHHHHHHHHHHHHHHT--S?TT-HHHHHTTS--------------------TTS?HHHHHHHHHHHHHHHSS?---?-?---------HHHHHHHHHHHHHHTHHHHHHHHHT?----??HHHHHHHHHHHHHHHHHHHHHH----------HHHH--------HHHHH???HHHHHHHH---HHHHTTSTHHHHH-HHHHHHHHHS-------???TTTHHHHHHHHHHHHHHHHS?TTSS???T------T??-EE???????-------?? 1Z2C|B PF06368.6_Met_asp_mut_E_seed 5 445 !Q:1,1|5,5|18,19|23,27|45,46|54,54|61,61|78,79|84,84|100,103|106,106|111,113|115,116|128,129|133,134|143,143|146,147|170,172|176,177|180,180|186,187|207,208|216,217|219,219|243,244|246,246|254,256|258,260|282,282|287,289|297,298|319,324|352,352|367,368|371,373|377,380|385,385|389,389|395,395|398,401|422,424|442,445 Q:0,0|2,4|6,17|20,22|28,44|47,53|55,60|62,77|80,83|85,99|104,105|107,110|114,114|117,127|130,132|135,142|144,145|148,169|173,175|178,179|181,185|188,206|209,215|218,218|220,242|245,245|247,253|257,257|261,281|283,286|290,296|299,318|325,351|353,366|369,370|374,376|381,384|386,388|390,394|396,397|402,421|425,441 S?GGG?HHHHHHHHHHHT??EEE?????SSHHHHHHHHHHHHHTT??SSEEEEB?TTGGGT?HHHHHHHHHHHHHHTS??SSSB?HHHHHHHHHHHHHHH?---SS?EEEE???S??HHHHHHHHHTT??EEE??TTTTTTTT?SS??HHHHHHHHHHHHHHHHHHHHTT???EEE??TT-TTSSS??HHHHHHHHHHHHHHHHHTT??EEEEEEE??S?HHHHHHHHHHHHHHHHHHHHHTT??S?EEEEEEE???S???SSHHHHHHHHHHHHHHHHHHT?SEEE???TTTTTSS??HHHHHHHHHHHHHHHHHTTT??????HHHHHHHHHHHHHHHHHHHHHHHHTTT?HHHHHHHHHHHTSS??TT???TTS????EEEE?TTS?EEEEE?TT????HHHHHHHHHHHHHHHHHHTS???HHHHHHHHHHTTTTSSS???- 1CCW|B PF06369.7_Anemone_cytotox_seed 3 177 !Q:0,4|11,12|24,24|26,26|41,41|52,52|54,54|57,59|63,63|74,75|79,82|95,95|104,104|106,106|110,112|122,126|138,139|142,142|154,154|163,163 Q:5,10|13,23|25,25|27,40|42,51|53,53|55,56|60,62|64,73|76,78|83,94|96,103|105,105|107,109|113,121|127,137|140,141|143,153|155,162|164,176 ?????EEEGGG??HHHHHHHHHHT?S?SSEEEEEEEEESSS?EEEEEEEEEE?B?SS???SEE?TTEEEEEEEE??SSS????EEEEEEEEETTS?EEEEEEEE?S?TTT???EEEEEEESS?????HHHHHHHHHTS??EE?SSEEEEEEEET-TEEEEEEE?SSSEEEEEEEEEE 1KD6|A PF06371.8_Drf_GBD_seed 20 244 !Q:0,10|21,23|25,26|31,33|40,40|55,95|107,108|112,122|138,138|146,146|164,183|210,212|223,224 Q:11,20|24,24|27,30|34,39|41,54|96,106|109,111|123,137|139,145|147,163|184,209|213,222|225,243 ????-??????HHHHHHHHHT---T??HHHH---HHHHSS?HHHHHHHHHHHHHH?????----------------------------????????HHHHHHHHTTT??HHH-----------HHHHHHHHHHHHHHS?HHHHHHH-HHHHHHHHHHHHHHHHT?????----------?????HHHHHHHHHHHHHHTSSHHHHHHHHT--?SSHHHHHHHT??TTSHHHHHHHHHHHHHHHT 1Z2C|B PF06372.7_Gemin6_seed 2 169 !Q:0,1|7,7|17,17|37,37|41,42|49,49|53,53|60,60|72,74|79,80|86,168 Q:2,6|8,16|18,36|38,40|43,48|50,52|54,59|61,71|75,78|81,85 ??HHHHS?HHHHHHTTT?EEEEEETTTEEEEEEEEEE?TTT??EEEEEE?TTS?EEEEEE?GGGEEEEEEEE???HHHH--HHHHT??--------------------------------------------------------------------------------- 1Y96|A PF06373.6_CART_seed 9 76 !Q:0,39|41,42|46,46|51,51|58,59|61,62|65,66|68,68|72,72|75,75 Q:40,40|43,45|47,50|52,57|60,60|63,64|67,67|69,71|73,74 -----------------------------------?????B??SSS?SEEE?SSSEEE??B??TT??B?TTT?SB? 1HY9|A PF06375.6_BLVR_seed 16 204 !Q:0,48|52,52|56,58|61,83|86,86|94,97|112,124|130,137|142,149|152,158|164,165|167,167|169,169|171,174|181,182|190,203 Q:49,51|53,55|59,60|84,85|87,93|98,111|125,129|138,141|150,151|159,163|166,166|168,168|170,170|175,180|183,189 --------------------?????????????????---------???TTS?EEE???SS----???-----???-------?SS?SSEEESS????EEEEEEEETTEEEE-------------EEESS-----???HHHH--------HH-------HHHTT--S?S-S----SEEEEE--EETTEEE-------------- 4AFI|A PF06384.6_ICAT_seed 8 81 !Q:0,9|30,33|53,62|64,74|76,80 Q:10,29|34,52|63,63|75,75 ??????????HHHHHHHHHHHHHHHHHHTT????HHHHHHHHHTHHHHHHHHT??????????S???????????S????? 1M1E|B PF06389.6_Filo_VP24_seed 3 255 !Q:0,9|11,14|22,23|30,30|35,35|52,52|64,67|83,83|89,90|107,115|130,132|135,137|146,146|168,170|172,172|175,178|184,184|187,187|194,194|204,204|207,207|211,213|217,219|234,254 Q:10,10|15,21|24,29|31,34|36,51|53,63|68,82|84,88|91,106|116,129|133,134|138,145|147,167|171,171|173,174|179,183|185,186|188,193|195,203|205,206|208,210|214,216|220,233 --------??S????HHHHHHH--HHHHHB?EEEE?SSEEEEEETTEEEEEE?TTHHHHHHHHS????GGGHHHHHHSHHHHS?TTEEE??HHHHHHHHHHHHHHTT?????????HHHHHHHHHHHHHH???SB???SSHHHHHH?SHHHHHHHHHHHHHHHHHHHT???S?SS????EEEEE?SS?EEEEEE?SSEEEEEEE?TT?GGG--?SSS???EEEEEEETTTTGGG??------------------- 4D9O|A PF06393.6_BID_seed 7 207 !Q:1,1|4,7|9,13|27,29|33,33|47,53|55,55|58,58|60,62|65,68|70,70|72,76|79,79|83,86|110,113|116,116|150,151|154,154|174,174|177,177|205,206 Q:0,0|2,3|8,8|14,26|30,32|34,46|54,54|56,57|59,59|63,64|69,69|71,71|77,78|80,82|87,109|114,115|117,149|152,153|155,173|175,176|178,204 S?SS?-??S?????THHHHHHHHHHHH---HTS?SSSHHHHHHHGGG--?????S?SS?S--?SS????S?S???-?TT?STT-???SHHHHHHHHHHHHHHHHHHHHTT--??TT?HHHHHHHHHSGGGHHHHHHHHHHHHHHHHHTTS??SS?SHHHHHHHHHHHHHHHHHH?TT?HHHHHHHHHHHHHTTTHHHHHHHHHTS?? 2BID|A PF06394.8_Pepsin-I3_seed 13 77 !Q:4,6|10,11|14,15|40,41|61,76 Q:0,3|7,9|12,13|16,39|42,60 HHHH???GGG??TT?-EEEEETTEEEETTEEEETTEEEEE??HHHHHHHHHHHHHHHHHHH???????????????? 1F32|A PF06395.6_CDC24_seed 17 96 !Q:0,1|28,28|33,33|35,38|40,40|46,46|64,66|71,72|78,79|81,81|83,83|96,96 Q:2,27|29,32|34,34|39,39|41,45|47,63|67,70|73,77|80,80|82,82|84,95 --HHHHHHHHSSTHHHHHHHHHHSTTSS?GGGS?S----S?TTBHH-HHHHHHHHHHHHHHHTT???TTSS??HHHHH--T?S?HHHHHHHHHHHH- 2D86|A PF06397.7_Desulfoferrod_N_seed 8 36 !Q:0,1|4,4|8,8|12,13|20,21|24,24|32,32|35,35 Q:2,3|5,7|9,11|14,19|22,23|25,31|33,34 ??TT?EEE?TTT??EEEEEE??SS?EEETTEE?EE? 1CFW|A PF06399.8_GFRP_seed 4 83 !Q:0,0|9,9|13,14|19,19|23,23|32,32|36,37|40,40|43,43|50,50|82,82 Q:1,8|10,12|15,18|20,22|24,31|33,35|38,39|41,42|44,49|51,81 ?EEEEEEES?TTS??EEEE?TTS?HHHHHHHT?EEE??TT?SS?EEEESS?HHHHHHHHHHTTEEEEEEEEETTEEEEEEEE? 1WPL|K PF06400.6_Alpha-2-MRAP_N_seed 10 136 !Q:0,44|46,49|66,68|92,92|98,100|102,102|121,133|135,135 Q:45,45|50,65|69,91|93,97|101,101|103,120|134,134 ----------------------??????---------????????S????SSSHHHHHHHHHHHHH???HHHHHHHHHHHHHHHHHHHHHHH-HHHHT???S?HHHHHHHHHHHHHHHHHT?----????????S? 1OP1|A PF06401.6_Alpha-2-MRAP_C_seed 11 250 !Q:0,0|2,3|19,21|54,87|92,95|97,97|101,102|137,138|140,140|143,144|159,160|204,204|241,243|249,249 Q:1,1|4,18|22,53|88,91|96,96|98,100|103,136|139,139|141,142|145,158|161,203|205,240|244,248 ?S??SHHHHHHHHHHHHHS???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT----------------------------------STTS????S?SSS??SSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS??S?SS??TTHHHHHHHHHHTT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSS?TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--?TTSTT? 2FTU|A PF06405.6_RCC_reductase_seed 8 308 !Q:20,21|23,28|36,38|53,53|56,56|58,94|107,107|109,110|113,113|125,125|128,132|151,153|156,156|160,160|175,175|185,185|191,193|195,195|203,203|206,206|213,213|216,219|248,250|254,259|288,288|292,292 Q:0,19|22,22|29,35|39,52|54,55|57,57|95,106|108,108|111,112|114,124|126,127|133,150|154,155|157,159|161,174|176,184|186,190|194,194|196,202|204,205|207,212|214,215|220,247|251,253|260,287|289,291|293,307 HHHHHHHHHHHHHHHHTTTT--B??????HHHHEEE?--TTSSEEEEEEEEEB?TT?S-------------------------------------EEEEEEEEEEEE?T--TS?EEEEEEEEEEE?TT?????EEEEEEESSSSEEEEEEE???SS?TTT?HHHHHHHTTSSSHH-HHHHHHHTS-TTEEE???S?HHHHHHS?TT?EEEEEE?SS----HHHHHHHHHHTHHHHHHHHHHHHHHHTT--?SSS??????HHHHHHHHHHHHHHHHHHHHHHTTTTHH-HHH?HHHHHHHHHHHHHHH 2ZXL|A PF06406.6_StbA_seed 7 333 !Q:0,0|7,7|10,10|17,18|22,22|29,31|36,39|41,43|47,52|59,59|65,68|71,76|98,99|110,110|116,116|122,122|136,137|139,140|144,144|146,148|170,171|173,173|176,176|184,184|187,187|198,199|209,209|224,226|244,244|253,254|283,286|289,289|310,311|317,321 Q:1,6|8,9|11,16|19,21|23,28|32,35|40,40|44,46|53,58|60,64|69,70|77,97|100,109|111,115|117,121|123,135|138,138|141,143|145,145|149,169|172,172|174,175|177,183|185,186|188,197|200,208|210,223|227,243|245,252|255,282|287,288|290,309|312,316|322,332 ?EEEEEE?SS?EEEEEE-?SSS?EEEEEE???EESS????S---SSS---???EEESSS-SEEEE????TT??????GGGGGSHHHHHHHHHHHHHHS??SSEEEEEEEE?HHHHB?TTSSB?HHHHHHHHHHTTS??E--ETT-B???EEEEEEEEESSGGGGHHHHHT--S?TT?EEEEEEE?SS?EEEEEEEGGG??EEEEEEETT?STHHHHHHHHHHHT?-?SSHHHHHHHHHHHHTTT?HHHHHHHS??HHHHHHHHHHHHHHHHHHHHHHHHHHTT????SE-EEEESTTHHHHHHHHHHHHT??GGGEE?????TTHHHHHHHHH 4A62|A PF06407.6_BDV_P40_seed 3 370 !Q:0,36|38,48|69,69|94,95|97,97|105,105|110,110|116,117|119,119|122,128|150,150|157,158|174,174|181,182|187,188|212,215|234,234|247,248|287,287|313,325|328,331|343,349|352,353|365,369 Q:37,37|49,68|70,93|96,96|98,104|106,109|111,115|118,118|120,121|129,149|151,156|159,173|175,180|183,186|189,211|216,233|235,246|249,286|288,312|326,327|332,342|350,351|354,364 ?????????????????????????????????????S???????????GGGHHHHHHHTTSHHHHTTB?TTHHHHHHHHHHSTTHHHHHHHTT??S?EEEEEEE?TTSS?EEEES??S?SS???????HHHHHHHHHHHHHHHHHHHHT?SHHHHS??HHHHHHHHHHHHHTT?TTHHHH??TTTT??THHHHHHHHTSTTHHHHHHHHHH????TTHHHHHHHHHHHHTTTT?HHHHHHHHHHHH??BGGGGSHHHHHHHHHHHHHHHHHHHHHGGGGGGTTTTT?GGGGGGSGGGSHHHHHHHHHHHHHH?????????????TT????HHHHHHHHTSB???????SS??HHHHHHHHHTT????? 1N93|X PF06411.6_HdeA_seed 33 115 !Q:0,46|50,50|59,59|76,76|78,79|81,81|84,89|106,106 Q:47,49|51,58|60,75|77,77|80,80|82,83|90,105|107,114 -------------------------???------------------?GGG?BHHHHHTS?HHHHHHHHHHHHHBTS-B??S?SB?--???HHHHHHHHHHHHHHHH?TTSBGGGG 1DJ8|A PF06414.7_Zeta_toxin_seed 40 280 !Q:7,22|25,25|33,33|50,55|58,59|63,63|72,87|96,98|100,101|113,116|133,134|139,140|150,150|157,161|163,163|166,166|174,176|195,195|197,221|225,229|244,247|252,252|255,266|270,271|279,279 Q:0,6|23,24|26,32|34,49|56,57|60,62|64,71|88,95|99,99|102,112|117,132|135,138|141,149|151,156|162,162|164,165|167,173|177,194|196,196|222,224|230,243|248,251|253,254|267,269|272,278 HHHHHTT--------??---??-SS?EEEEEES?GGGTTHHHHHHHHHHT------TT??EEE?GGGGGTTS----------------TTHHHHHT---T-?SSTTHHHHHHH----HHHHHHHHHHHHHHTT??EEEE??TTSSHHHHH-HHHHHH-----H-TT?EEEEEEE???HHHHHHHHHHHHHHTTTS?S--------???-----?????????TTH-----HHHHHHHHHHHHTT--??SEEE-EE-----------?TTS-?EEEETTT? 3ZN8|D PF06415.8_iPGM_N_seed 35 242 !Q:8,8|12,12|27,28|35,35|38,39|42,43|59,61|69,69|74,74|77,77|92,92|95,99|110,110|113,115|117,118|131,132|134,135|137,138|142,142|151,153|158,159|163,165|170,170|174,174|177,180|183,183|188,191|204,204|207,209|212,214|217,219|221,222|229,231|235,235|237,237 Q:0,7|9,11|13,26|29,34|36,37|40,41|44,58|62,68|70,73|75,76|78,91|93,94|100,109|111,112|116,116|119,130|133,133|136,136|139,141|143,150|154,157|160,162|166,169|171,173|175,176|181,182|184,187|192,203|205,206|210,211|215,216|220,220|223,228|232,234|236,236|238,241 HHHHHHTT?GGG?HHHHHHHHHHHHTT??EEEEEE?SS??SS??HHHHHHHHHHHHHHT???EEEEEEE?SSSS?TT?HHHHHHHHHHHHHH-HT??---EEEEEEEHHH-HT??-S??HHHHHHHHHHHH--H??S?-EES?HHHHHHHH---HHTT??GGG???EEEB?TTS?BS????TT?EEEE????STTTHHHHHHHH?SS-??SS???TT???S?-EEEEEE???TTS?S-EEEE 1O99|A PF06416.7_DUF1076_seed 12 128 !Q:0,9|12,26|28,31|40,40|43,44|50,51|56,56|63,64|95,97|101,105|111,111|127,127 Q:10,11|27,27|32,39|41,42|45,49|52,55|57,62|65,94|98,100|106,110|112,126 ---------?HH---------------H----HHHHHHHH?EE??TTTTT??TGGG?BTTTTB??SEEEEEEETTTTSEEEEEEHHHHHHHHHHT???TTT?????TTTEE?TTSEEEETTTTEEEE? 2KKX|A PF06418.9_CTP_synth_N_seed 98 334 !Q:0,0|8,8|12,12|14,14|22,22|32,33|41,44|46,46|51,51|56,57|61,61|64,78|91,91|94,98|108,114|129,129|131,134|149,153|156,156|159,171|173,176|184,184|186,186|207,208|220,221|230,231|246,248|258,261|274,275|284,285|287,288|310,316|318,330 Q:1,7|9,11|13,13|15,21|23,31|34,40|45,45|47,50|52,55|58,60|62,63|79,90|92,93|99,107|115,128|130,130|135,148|154,155|157,158|172,172|177,183|185,185|187,206|209,219|222,229|232,245|249,257|262,273|276,283|286,286|289,309|317,317|331,333 ?EEEEEEE?SSS?S?HHHHHHH-HHHHHHTTT??EEEEEEE????S?TTSS?HHHH??EEE?TT?-------------?EEETHHHHHHTT?SS???--GGGEEEHHH-------HHHHHHHHHHTTTT?S????TTTHHHHHHHHHHH-----HH-TT-------------T---?SEEEEEE?S?TTSGGGHHHHHHHHHHHHHH-?TTSEEEEEEEE??EETTTTEE??HHHHHHHHHHHTTT???SEEEEEESS?-??HHHHHHHHHHHT??GGGEEEEE??S-?GGGHHHHHHHTTHHHHHHHHT-------T??--????-??--HHH 2VO1|A PF06421.7_LepA_C_seed 45 114 !Q:5,5|9,9|33,33|35,35|38,38|48,49|58,61|64,113 Q:0,4|6,8|10,32|34,34|36,37|39,47|50,57|62,63 ETTEE?GGG?EEEEGGGHHHHHHHHHHHHHHHS?S?SS?EEEEEEETT--EEEEEEEE????TT----?????????????????????????????????????????????? 3CB4|A PF06426.9_SATase_N_seed 111 124 !Q:15,15|29,29|45,46|48,48|51,53|68,69|71,82|90,91|101,101|104,107|115,115 Q:0,14|16,28|30,44|47,47|49,50|54,67|70,70|83,89|92,100|102,103|108,114|116,123 HHHHHHHHHHHHHHH?GGGHHHHHHHTTT?SSHHHHHHHHHHHHH??S-SS?--HHHHHHHHHHHHHH-?T------------HHHHHHH--HHHHHHHHH?TT???-SHHHHHH?HHHHHHHH 1SST|A PF06428.6_Sec2p_seed 20 127 !Q:39,42|86,126 Q:0,38|43,85 HHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHH----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS?---------------------?????------------?? 2OCY|A PF06429.8_Flg_bbr_C_seed 463 129 !Q:4,6|8,8|12,13|15,17|19,20|22,31|33,33|35,40|42,42|45,52|54,54|59,69|71,93|124,124 Q:0,3|7,7|9,11|14,14|18,18|21,21|32,32|34,34|41,41|43,44|53,53|55,58|70,70|94,123|125,128 GGSE---E?STT?-E---E??T----------T-T??--?-E-EE-?------T-TBTT-----------B?-?---?--?????--???????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHT 3A69|A PF06431.6_Polyoma_lg_T_C_seed 3 425 !Q:0,4|17,19|33,33|37,37|44,45|65,65|67,67|91,91|115,118|150,151|154,155|161,162|179,179|184,186|188,188|202,202|211,212|215,215|220,223|232,232|238,238|241,241|255,258|264,264|266,269|276,276|282,285|295,295|303,303|306,306|319,319|324,324|342,343|359,359|362,424 Q:5,16|20,32|34,36|38,43|46,64|66,66|68,90|92,114|119,149|152,153|156,160|163,178|180,183|187,187|189,201|203,210|213,214|216,219|224,231|233,237|239,240|242,254|259,263|265,265|270,275|277,281|286,294|296,302|304,305|307,318|320,323|325,341|344,358|360,361 ?????HHHHHHHHHHHT???HHHHHHHHGGGGS?TTT?HHHHTT??HHHHTTHHHHHHHHHHHTT?S?HHHHHHHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHTSTT????HHHHHHHHHHHTTTSTTHHHHHHHHHHHHHH??TT??EEEEE??TTSSHHHHHHHHHHHH?EEEE???S?TTTHHHHHGGGTT?SEEEEEEE??SS?TTTT????SHHHHHTT?HHHHH?SS?EEEEETTEEEEEE????EEEEE?S????HHHHTT?SEEEE????HHHHHHHHT?THHHHTT?TT?HHHHHHHHHHHS?GGGS?HHHHHHHHHHHHHHHHH??HHHHHHHHHHHHTTS?TT?-------------------------------------------------------------- 1SVO|A PF06433.6_Me-amine-dh_H_seed 5 343 !Q:0,0|9,9|13,13|35,35|38,38|43,43|48,48|72,72|76,77|87,91|94,95|102,102|113,113|117,117|135,136|157,157|163,164|168,169|171,171|175,178|180,180|184,184|186,186|188,189|212,212|217,217|220,222|227,227|238,238|242,242|259,260|263,263|267,267|279,280|292,292|297,298|302,302|322,323|329,332|335,336|341,342 Q:1,8|10,12|14,34|36,37|39,42|44,47|49,71|73,75|78,86|92,93|96,101|103,112|114,116|118,134|137,156|158,162|165,167|170,170|172,174|179,179|181,183|185,185|187,187|190,211|213,216|218,219|223,226|228,237|239,241|243,258|261,262|264,266|268,278|281,291|293,296|299,301|303,321|324,328|333,334|337,340 ?TTEEEEEE?GGG?SSEEEEEEETTTTEEEEEEEE?SS?EEEE?TTSS?EEEEEEEEEETTEEEEEEEEEEE?TTT??EEEEEEETT?????BS??GGGEEE?TTSSEEEEEE?SSS?EEEEEETTTTEEEEEEE??SEEEEEEEETTEEEEEETTS?EEEEE??SSS??E-EEE????S?TTS?B?S??EEETTTTEEEEEBTTSEEEEEE?TTSS?EE???EESS?HHHHHTTEEE?SSS?EEEETTTTEEEEEEEE??TT?TTS?EEEEEEEETTT??EEEEEEEEEEE?EEEE??SSS?EEEEEETTTTEEEEEETTT??EEEEE????SS??EEEE?? 2J55|H PF06434.8_Aconitase_2_N_seed 94 386 !Q:6,6|17,17|36,36|38,38|43,44|47,48|53,53|63,63|68,72|84,86|94,94|111,112|119,119|121,121|133,133|135,158|162,165|168,169|172,174|180,181|190,193|197,316|321,323|325,325|356,363|366,382|384,385 Q:0,5|7,16|18,35|37,37|39,42|45,46|49,52|54,62|64,67|73,83|87,93|95,110|113,118|120,120|122,132|134,134|159,161|166,167|170,171|175,179|182,189|194,196|317,320|324,324|326,355|364,365|383,383 EEEEEE-EEEEEHHHHS?GGGGGGTTSHHHHGGGTT?S?BTTB??SB--TTTB?SHHHHHHHH-TTSS?----EEEEEEEEEES???THHHHHH-HHHHSEEETTEEEEEE??EEEEEE-E?HHHHHHHHHTT?E------------------------EEE-???TT??TT?--EEEEE--TTTTEEEE----TTT?-------------------------------------------------------------------------------------------------------------------?---EEEE???S?THHHHHHHHTSHHHHHHHHHHHHHHHHHTT?---????SS???------?????-??S?? 1L5J|A PF06435.6_DUF1079_seed 4 31 !Q:17,17 Q:0,16|18,30 HHHHHHHHHHHHHHHHH-HHHHHHHHHHHHH 2QIH|A PF06436.6_Pneumovirus_M2_seed 4 159 !Q:0,33|35,40|45,45|60,62|78,78|90,90|93,93|112,112|124,124|143,144|146,158 Q:34,34|41,44|46,59|63,77|79,89|91,92|94,111|113,123|125,142|145,145 -----------------------------?????S??????SSTT?SHHHHHHHHHHTSS???HHHHHHHHHHHHTTS?HHHHHHHHHTS?TT?THHHHHHHHHHHHHHHHH?HHHHHHHHHHS?HHHHHHHHHHHHHHHHHT??S???---------- 2L9J|A PF06438.7_HasA_seed 7 234 !Q:0,2|7,7|27,32|35,39|44,44|51,52|62,62|67,67|76,79|83,83|90,97|99,99|114,116|118,119|122,122|124,127|138,140|144,144|151,156|158,158|171,172|185,186|190,191|204,233 Q:3,6|8,26|33,34|40,43|45,50|53,61|63,66|68,75|80,82|84,89|98,98|100,113|117,117|120,121|123,123|128,137|141,143|145,150|157,157|159,170|173,184|187,189|192,203 ???EEEE?GGGTTSBHHHHHHHHHHHH??????TT??--?GGGS?EEESSS--SEEEEEEEE?TTTS?EEEEEEEE----EEE?TTSSST--------T?EEEEEEEEEEEEEE---E??SS-S?--?EEEEEEEEEE???EEE?GGGGGG------S-HHHHHHHHHHTT??HHHHHHHHHHHG--GGT??TTSBHHHHHHHH?---------------?????????????? 4JET|A PF06439.6_DUF1080_seed 189 533 !Q:0,4|8,19|22,26|29,32|35,37|44,45|48,103|109,109|111,135|140,160|162,166|168,170|175,177|179,180|183,183|192,192|195,211|213,214|216,230|239,269|273,278|284,285|291,297|301,301|305,320|337,384|386,395|397,399|401,405|409,409|415,415|422,433|436,436|438,438|468,470|473,474|488,488|494,495|498,508|510,520|524,525 Q:5,7|20,21|27,28|33,34|38,43|46,47|104,108|110,110|136,139|161,161|167,167|171,174|178,178|181,182|184,191|193,194|212,212|215,215|231,238|270,272|279,283|286,290|298,300|302,304|321,336|385,385|396,396|400,400|406,408|410,414|416,421|434,435|437,437|439,467|471,472|475,487|489,493|496,497|509,509|521,523|526,532 ??---EES?--?--------SS--??-TT----EE---ETTSSS??TT--------------------------------------------------------EEEET-T-------------------------EEEE------------------???S?????S???EEES---S-?BS-SEEEEEEE-EE----------------?B--T?--------------EEEEEEEE?----------------------------??TTS-----?GGGSS?-EEEEE?------TTT?GGG----------------SSSSTTTTSTTSBTTT------------------------------------------------B?--------?S---S?????TTS?EEEEE-EEETTE------------EE-E-EETTEEEEEEETTSHHHHHHHHTSTTSTT???TT??GGGHHHHHTTTSS?BEEEE?-TT?----------T-----------TEE--EEEEEEE 4AZZ|A PF06440.6_DNA_pol3_theta_seed 11 81 !Q:0,5|8,9|33,37|45,46|72,77|80,80 Q:6,7|10,32|38,44|47,71|78,79 ?--???TT??SHHHHHHHHHHHHHHHHHHHHHT?????HHHHHTS??GGGHHHHHHHHHHHHHHHHHSSTTS-----?SS? 1SE7|A PF06441.7_EHN_seed 143 214 !Q:3,11|25,38|40,51|54,54|58,58|70,97|100,100|102,121|131,133|136,136|143,150|152,169|179,186|190,190|192,192|194,194|200,201|204,205 Q:0,2|12,24|39,39|52,53|55,57|59,69|98,99|101,101|122,130|134,135|137,142|151,151|170,178|187,189|191,191|193,193|195,199|202,203|206,213 EEE----?????HHHHHHHHHHHHT???---?-???-??T------------TT-TSS?HHHHHHHHHHH----------------------------HH-T?--?----------------HHHHHHHHH---TS?EEEEEE--------T------------------TEEEEEEEE??------SST-T?E-EEEEE??TT??GGGGHHHH 1EHY|A PF06442.6_DHFR_2_seed 3 78 !Q:0,24|27,27|36,37|46,47|50,50|64,64|76,77 Q:25,26|28,35|38,45|48,49|51,63|65,75 ----------------?????????TT?EEEESSSS??EEEEEEEE??SS?SSEEEEEESSSTT?EEEEEGGGEEE?? 3SFM|A PF06445.10_GyrI-like_seed 88 226 !Q:0,2|8,9|20,20|25,35|41,41|53,72|80,80|82,82|85,89|92,92|96,96|105,105|108,130|133,133|136,136|142,143|145,145|154,154|156,156|158,163|165,166|180,180|184,187|190,190|193,193|199,199|201,201|204,210|218,218 Q:3,7|10,19|21,24|36,40|42,52|73,79|81,81|83,84|90,91|93,95|97,104|106,107|131,132|134,135|137,141|144,144|146,153|155,155|157,157|164,164|167,179|181,183|188,189|191,192|194,198|200,200|202,203|211,217|219,225 ???EEEEE??EEEEEEEEES?HHHH-----------HHHHH-HHHHHHHHHTT?-----------------??SEEEEEE?S?TT-----TS?GGG?EEEEEEEE?TT????-------------------SS?TT?EEEEE??E-EEEEEEEE-E?S------S??HHHHHHHHHHHTT?SSE----EE?SS?EEEEE?S?HH-------HHSSEEE-EEEEEEE 1D5Y|A PF06446.7_Hepcidin_seed 20 63 !Q:0,35|38,40|45,45|48,49|54,55|60,62 Q:36,37|41,44|46,47|50,53|56,59 ---------------------------------??-SS???EEEE?SS--SSSS--EEEE??? 1S6W|A PF06451.6_Moricin_seed 2 41 !Q:0,2|35,36|38,40 Q:3,34|37,37 ???SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT??S??? 1X22|A PF06452.6_DUF1083_seed 35 247 !Q:1,1|5,7|14,16|20,21|25,28|31,31|33,35|39,39|48,49|61,61|64,68|73,76|90,96|99,100|112,113|116,119|121,121|124,136|149,149|153,157|165,177|180,188|193,195|205,205|207,207|211,211|220,220|224,224|226,231|234,234|245,247 Q:0,0|2,4|8,13|17,19|22,24|29,30|32,32|36,38|40,47|50,60|62,63|69,72|77,89|97,98|101,111|114,115|120,120|122,123|137,148|150,152|158,164|178,179|189,192|196,204|206,206|208,210|212,219|221,223|225,225|232,233|235,244 S-SSS?-?GGGGGS?--EEE??EEE----ES?T---TTS?EEEEEEEE?-SSEEEEEEEEE?SS-????SSSG----GGSSEEEEEEESS???---?SS??TTEEEEEEETT??EE----E?TT?-----------?GGGEEEEEEEET-TEE-----EEEEEEE?------------SS?-----???TTEE---EEEEEEEEE-E?TTS?EEEEEESS?SSS?T------TT?GGGSEEEEEE-?- 1I8A|A PF06453.6_LT-IIB_seed 2 122 !Q:0,25|44,44|52,52|57,57|67,67|72,74|97,99|105,105|120,121 Q:26,43|45,51|53,56|58,66|68,71|75,96|100,104|106,119 -----------------------???HHHHHHHHTSSSEEEEEE?EEEEEEE?STTT?EEEEEETTS?EEEE???SSTTHHHHHHHHHHHHHHHHHH???EEEEE?SSSSSEEEEEEEEE?? 4FO2|A PF06456.8_Arfaptin_seed 11 245 !Q:0,38|89,90|92,92|164,165|169,197|241,245 Q:39,88|91,91|93,163|166,168|198,240 -----------------------------???----???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--T?GGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--TTT????????????????---------????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT????- 1I4T|A PF06457.6_Ectatomin_seed 2 34 !Q:0,1|20,20|33,33 Q:2,19|21,32 ??HHHHHHHHHHHHHHHHTB?HHHHHHHHHHHH? 1ECI|A PF06458.7_MucBP_seed 115 189 !Q:14,14|16,21|23,23|27,27|35,36|40,52|56,56|61,64|68,96|98,98|100,110|114,118|121,128|132,141|145,145|149,150|154,162|165,167|170,171|175,175|178,178|182,188 Q:0,13|15,15|22,22|24,26|28,34|37,39|53,55|57,60|65,67|97,97|99,99|111,113|119,120|129,131|142,144|146,148|151,153|163,164|168,169|172,174|176,177|179,181 SEEEEEEEEEEEET-T------S?EEE-EEEEEEE--EEE------??-----EEE-ETTT--??EEE--------------------------???S?S-----------EEE?--??EE??--??--TTE----------EES?SEE??EEE---------TT?--SS??EEE-EE-EEE------- 3Q69|A PF06460.7_NSP13_seed 8 316 !Q:0,1|9,10|16,28|30,31|35,35|38,39|56,60|63,63|70,72|77,77|88,98|101,101|110,111|113,113|122,122|131,131|138,145|149,149|152,152|154,159|166,166|185,185|189,191|217,217|226,226|229,231|234,236|251,257|262,263|266,266|268,273|277,279|283,284|295,295|299,305|309,315 Q:2,8|11,15|29,29|32,34|36,37|40,55|61,62|64,69|73,76|78,87|99,100|102,109|112,112|114,121|123,130|132,137|146,148|150,151|153,153|160,165|167,184|186,188|192,216|218,225|227,228|232,233|237,250|258,261|264,265|267,267|274,276|280,282|285,294|296,298|306,308 ??TTSSEEE??HHHHT?????????????S??TTS?TT??HHHHHHHHHHHHHTTS?????TT?EEEEES???TTSB?HHHHHHHHHS----------?TT?EEEEEESS??B?SSSEEEES?GGGEEESS?EEEEEE???----?TTS?SS?S??????THHHHH-HHHHHHHEEEEEEEEEEE?SSS?-?HHHHHHHTTEEEEEEEEEGGGTTSS?EEEEEEEE?SS--?SS???HHHHHHHHHHHHHH???????GGGG??TT?S??????EEE???GGG??HHHHHHHHTT?EEE???????EEE?????-? 3R24|A PF06463.8_Mob_synth_C_seed 66 177 !Q:0,0|7,9|11,11|17,22|25,27|40,40|42,43|46,48|52,54|56,56|64,74|78,80|82,102|107,107|112,114|118,119|124,124|134,135|138,139|149,152|156,158|170,173 Q:1,6|10,10|12,16|23,24|28,39|41,41|44,45|49,51|55,55|57,63|75,77|81,81|103,106|108,111|115,117|120,123|125,133|136,137|140,148|153,155|159,169|174,176 ?EEEEEE???B?SSSSB-??---SS???HHHHHHHHHHHS?E--EE???SST---T?SSEEEEE-----------SSS?-?E---------------------EEEE?TTTS?-?GGG??EEEE?TTSEEESSS??SS??EEHHHHHHT??-?HHH---HHHHHHHHHHT????HHH 2FB3|A PF06467.9_zf-FCS_seed 56 53 !Q:0,0|3,3|6,6|8,8|12,13|15,17|21,27|30,30|32,37|39,41 Q:1,2|4,5|7,7|9,11|14,14|18,20|28,29|31,31|38,38|42,52 ?SS?SS?B?TTT??B?-?TTS?-----?EE?T------T???EESSHHHHHHH 1FFK|R PF06468.8_Spond_N_seed 17 240 !Q:0,0|10,12|16,17|20,22|26,26|38,38|41,42|44,45|49,51|61,63|73,74|80,116|118,118|125,127|129,130|136,136|147,147|150,150|161,161|173,173|178,178|181,181|189,190|193,193|197,199|203,206|208,208|211,214|217,218|223,224|227,227|230,231|237,239 Q:1,9|13,15|18,19|23,25|27,37|39,40|43,43|46,48|52,60|64,72|75,79|117,117|119,124|128,128|131,135|137,146|148,149|151,160|162,172|174,177|179,180|182,188|191,192|194,196|200,202|207,207|209,210|215,216|219,222|225,226|228,229|232,236 ?EEEEEEEEE???TTT??TT???SSS?SEEEEEEEEEE?TT??S??TTS???HHHHHHHHH???HHHHHHHHH--HHHHH-------------------------------------S?EEEEEE---E??BSSTT?EEEEEEEEBT-TB?EEEEEEEEES?SSEEEEEEEEE?EETT-EE?SEEEEEE??EE?SSB???STT????B?SS????EE??SSSS??TT?TT??TTSSS??? 3D34|A PF06470.8_SMC_hinge_seed 102 176 !Q:0,1|3,3|12,12|15,15|17,17|22,23|25,25|37,38|56,56|59,66|68,78|85,91|93,129|140,144|152,153|165,165|170,171 Q:2,2|4,11|13,14|16,16|18,21|24,24|26,36|39,55|57,58|67,67|79,84|92,92|130,139|145,151|154,164|166,169|172,175 ??S-EEEEHHHH?EE-S?GGGH--H-HHHHHHGGGGG-?EEESSHHHHHHHHHHHH-HT--------T-----????-?EEETTT???????S?------------------------------------SSEEGGGGEE?-?--GGGHHHH--HHHHTTEEEES?SGGG--GGGT 3L51|A PF06475.6_Glycolipid_bind_seed 30 207 !Q:7,9|13,14|21,21|23,24|35,40|44,45|47,47|57,57|61,61|83,83|87,87|93,97|99,99|105,106|113,113|125,127|129,130|132,132|147,149|160,161|164,167|175,175|179,184|191,191|195,195|206,206 Q:0,6|10,12|15,20|22,22|25,34|41,43|46,46|48,56|58,60|62,82|84,86|88,92|98,98|100,104|107,112|114,124|128,128|131,131|133,146|150,159|162,163|168,174|176,178|185,190|192,194|196,205 EEEEEEE???EEE??EEEEEE?S--SEEEEEEEEE?-----TTT??E-EEEEEEEEE?TTS?EEEEEEEEEETTEEEEEEEEE?SSS?EEETT??---B?GGGTT??EEEEET?GGGGHHHHHHH???T--T?EEEEEEEEEETTTT?-?EEEEEEEEEE--ET----TEEEEEE?SSS----??EEEEEE?TTS?EEEETTTEEE? 2H1T|A PF06479.7_Ribonuc_2-5A_seed 32 152 !Q:12,12|14,14|16,16|19,21|30,30|32,32|37,38|40,40|42,42|48,48|58,60|62,77|80,80|99,100|108,108|122,122|135,137|149,151 Q:0,11|13,13|15,15|17,18|22,29|31,31|33,36|39,39|41,41|43,47|49,57|61,61|78,79|81,98|101,107|109,121|123,134|138,148 HHHHHHHHHHHH?S?S?SS--?HHHHHHHH-T?STTT--T-S?GGGSS?HHHHHHTSS?-?S--------------??SS?HHHHHHHHHHHHHTTTTS-?HHHHHHH?STTHHHHHHHHSS?TTHHHHHHHHGG---GGSSSGGGTTT??? 3LJ0|A PF06480.10_FtsH_ext_seed 164 228 !Q:0,60|65,66|68,69|73,81|88,90|93,93|101,111|121,168|171,171|174,174|178,179|184,184|186,189|197,209|218,218|220,221|225,227 Q:61,64|67,67|70,72|82,87|91,92|94,100|112,120|169,170|172,173|175,177|180,183|185,185|190,196|210,217|219,219|222,224 -------------------------------------------------------------SSEE??H--HHH---------HHHTGG---GT?EEEEEEE-----------TTTEEEEEE-----------------------------------------------?TT-TS?STT??EEEE?S?---HHHHHHH-------------HHHHHHHT-T??TTT??? 2LNA|A PF06481.9_COX_ARM_seed 98 56 !Q:1,4|6,7|9,10|12,13|22,24|27,27|30,31|37,37|39,39|52,55 Q:0,0|5,5|8,8|11,11|14,21|25,26|28,29|32,36|38,38|40,51 H----H?-S??B??HHHHHHHT---SS?SS??SEEES?B?TTHHHHHHHHTT???? 1FFT|B PF06482.6_Endostatin_seed 11 380 !Q:0,199|202,203|209,209|212,212|214,214|236,237|239,239|244,245|250,250|256,256|263,264|267,267|271,271|276,276|285,285|288,289|292,294|300,300|305,305|308,308|311,311|315,316|318,318|322,322|324,324|334,336|348,348|353,355|363,363|366,366|371,371|373,379 Q:200,201|204,208|210,211|213,213|215,235|238,238|240,243|246,249|251,255|257,262|265,266|268,270|272,275|277,284|286,287|290,291|295,299|301,304|306,307|309,310|312,314|317,317|319,321|323,323|325,333|337,347|349,352|356,362|364,365|367,370|372,372 --------------------------------------------------------???------------------------------------------------------------------------------------------------------------------------------------?---?????SS??EEEEE?SS?B?SBSSHHHHHHHHHHHHHHHTT??S?EEES??BTTB?GGGGS?GGGSSS??EE?TTS?EEES?SGGGGSSS?SB??TT???BBTTS?BTTT?TT?SS?EEE??B?TTS?B?TTSBHHHHB???TTSEEEEEEGG-GTBS???EEEESSS?BB?EEEE?S??????? 1DY1|A PF06486.6_DUF1093_seed 59 109 !Q:0,0|3,5|12,20|30,35|38,39|49,49|52,53|60,62|66,70|72,74|89,100|105,105 Q:1,2|6,11|21,29|36,37|40,48|50,51|54,59|63,65|71,71|75,88|101,104|106,108 ?TT???EEEEEE????---??EEGGGGTTT------SS??EEEEEEEEE?SS??EEEEEE---EES-----S???TTSEEEEEEBTTTB---------???EEEE?TTT 2K5Q|A PF06487.7_SAP18_seed 26 200 !Q:0,5|10,11|24,26|31,55|57,59|61,64|66,67|73,73|76,76|88,92|94,94|102,102|112,112|116,124|138,139|142,143|145,178|182,182|189,190|193,193 Q:6,9|12,23|27,30|56,56|60,60|65,65|68,72|74,75|77,87|93,93|95,101|103,111|113,115|125,137|140,141|144,144|179,181|183,188|191,192|194,199 ??????GGGS??EEEEEEEESSSS???GGGG?------------------------T---T???-S??EEEEE?TT?BHHHHHHHHHH-----H?GGGGSTT?EEEEEEEEE?SSS---------SSEEEEEEEEEET--TB??T----------------------------------TTT?BTGGGT??TT?EEEEEE 4A6Q|A PF06491.6_Disulph_isomer_seed 28 141 !Q:17,17|20,21|32,33|35,36|45,45|65,65|68,69|90,90|93,93|96,99|116,116|124,124|140,140 Q:0,16|18,19|22,31|34,34|37,44|46,64|66,67|70,89|91,92|94,95|100,115|117,123|125,139 HHHHHHHHHHHHHHTTT?EE??SHHHHHHHHH--H??SEEEEEEE?SSHHHHHTHHHHHHHHHHH?SS??SEEEEEETTTSHHHHHHHHT-TS-TT????SSEEEEEETTEEEEEE?GGGTTTS?HHHHHHHHHHHHHHH? 3FHK|A PF06500.6_DUF1100_seed 5 416 !Q:0,18|22,22|24,24|26,26|31,32|43,44|46,46|49,51|60,61|75,76|78,78|84,84|87,87|89,89|95,95|115,115|118,118|138,139|142,142|174,174|177,177|188,189|193,193|201,202|205,206|223,223|229,230|240,242|244,244|259,259|290,290|298,300|306,306|314,314|327,327|331,331|343,343|353,354|358,358|363,363|367,367|371,371|385,386|388,389|391,391|415,415 Q:19,21|23,23|25,25|27,30|33,42|45,45|47,48|52,59|62,74|77,77|79,83|85,86|88,88|90,94|96,114|116,117|119,137|140,141|143,173|175,176|178,187|190,192|194,200|203,204|207,222|224,228|231,239|243,243|245,258|260,289|291,297|301,305|307,313|315,326|328,330|332,342|344,352|355,357|359,362|364,366|368,370|372,384|387,387|390,390|392,414 ???????????????????GGG?S?B?HHHH--HHHHHHHHHH??S?SS???HHHHHHTT??HHHHHHHHHHHHH??S?BSSTT?TT?B?SSSTT?HHHHHHHHHHHHHHGGGGS?HH-HHHHHHHHHHHHHHHHHTT??TT?HHHHHHHHHHHHHHHHHHHTSSSEEEEEEEE?SS-SEEEEEEEES?-SSS?EEEEEEE??TT??GGGGHHHHHTTTGGGT?EEEEE??TTSGGGTTS???S?TTHHHHHHHHHGGG?TTEEEEEEEEEEETHHHHHHHHHHHHTGGG?SEEEEES???SGGGS?HHHHTTS?HHHHHHHHHHTT?SSB?HHHHHHHGGGG?STTTSSSSS??BSS?EEEE?BTT?SSS?TTHHHHHHHTBTT??B??B?STTTTHHHHHHHHHHHHHHHHHT? 3OUR|A PF06506.6_PrpR_N_seed 47 204 !Q:9,9|13,14|17,19|34,34|36,37|46,46|55,56|59,59|64,66|79,83|86,90|92,92|101,103|106,109|118,118|120,123|147,150|163,163|175,176|194,203 Q:0,8|10,12|15,16|20,33|35,35|38,45|47,54|57,58|60,63|67,78|84,85|91,91|93,100|104,105|110,117|119,119|124,146|151,162|164,174|177,193 HHHTTTTTT?EEE--EE???HHHHHHHHHHHTTT-S??SEEEEEHH-HHHHHHTT?-SS?EEEE???HHHHHHHHHHTT----?TT-----S?EEEEEESS??-HH----HHHHHHHH-T?--?EEEEEESSHHHHHHHHHHHHHTT--??EEEESHHHHHHH-HHTTSEEEESS?-HHHHHHHHHHHHHHHHH????---??? 2PJU|A PF06508.8_QueC_seed 33 252 !Q:5,6|22,24|36,36|38,38|40,40|54,66|72,72|80,82|87,117|137,137|142,152|171,176|180,181|184,184|186,186|191,192|205,208|216,218|223,230|233,234|236,236 Q:0,4|7,21|25,35|37,37|39,39|41,53|67,71|73,79|83,86|118,136|138,141|153,170|177,179|182,183|185,185|187,190|193,204|209,215|219,222|231,232|235,235|237,251 EEEEE??SSHHHHHHHHHHHHH?--SEEEEEEEESS?T-T?HHHHHHHHHHHTT?---------?-?EEEEE?GGGGGGS---TGGG??????-???---??--------????????TTHHHHHHHHHHHHHHHHT?SEEE???????????GGGSHHHHHHHHHHHHHH------HTS??EE-E?TTTT??HHHHHHHHHHTT---?HHHHHHH???STTS------??SS??S?SHHHHHHHHHHHHHH 3BL5|A PF06511.6_IpaD_seed 3 370 !Q:0,8|37,46|63,63|65,72|74,75|102,106|124,125|146,148|196,209|226,227|231,232|240,242|246,249|251,251|264,268|272,273|278,278|287,289|303,311|363,369 Q:9,36|47,62|64,64|73,73|76,101|107,123|126,145|149,195|210,225|228,230|233,239|243,245|250,250|252,263|269,271|274,277|279,286|290,302|312,362 ?????????THHHHHHHHHHHHHHHHHHHHHHHHHHH----------HHHHHHHHHHHHHHSS?S????????S??TTTTHHHHHHHHHHHHHHHHHHHHHS?????HHHHHHHHHHHHHHHSS??HHHHTTSHHHHHHHHHHHHT???HHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHGGG?????-????????HHHHHHHHHHHHHHTS??TTS??STTEEES???SSS????B?HHHHHHHHHHTT?????TTS??SEEE?TTSSEEEE???HHHHHHHHHHHHT?????????TTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??????? 3O02|A PF06514.6_PsbU_seed 24 98 !Q:0,0|12,13|22,22|44,49|58,58|61,62|78,82|93,94|96,97 Q:1,11|14,21|23,43|50,57|59,60|63,77|83,92|95,95 ?HHHHHTTSSBT--TBEETTSS?GGGGGGSTTTTHHHHHHHHHS??---?SSGGGGGG?TT??HHHHHHHHHHGGGEE?????HHHHGGGTTT??S?? 3PRR|U PF06518.6_DUF1104_seed 12 94 !Q:0,0|6,6|18,18|37,37|60,60|80,83|85,88 Q:1,5|7,17|19,36|38,59|61,79|84,84|89,93 ?SSTTS?HHHHHHTTTTS?GGGHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHTTS?HHHHHHHHHHHHHHHHHTT????S----STTGG 2XRH|A PF06519.6_TolA_seed 9 100 !Q:0,9|27,27|36,37|45,45|49,52|62,62|73,73|77,82|84,84|86,86|95,95 Q:10,26|28,35|38,44|46,48|53,61|63,72|74,76|83,83|85,85|87,94|96,99 ??????????HHHHHHHHHHHHHHHTT?TTGGGGTT??EEEEEEE?TTS?---EEEEEEEEE?HHHHHHHHHH-HHH??????S?H-HHHHHHTT?EEEE 1TOL|A PF06526.7_DUF1107_seed 21 66 !Q:0,0|6,7|19,19|39,43|46,47 Q:1,5|8,18|20,38|44,45|48,65 ?EEESS??HHHHHHHHHHH?SEEEEETTTEEEEEETTEE??--?SS??HHHHHHHHHHHHHHHHHH 2JRO|A PF06534.8_RGM_C_seed 23 245 !Q:2,3|13,16|19,19|23,23|29,40|43,44|47,57|61,70|104,107|110,115|120,122|126,245 Q:0,1|4,12|17,18|20,22|24,28|41,42|45,46|58,60|71,103|108,109|116,119|123,125 TB??EEEEEETTB--??SS?TTS?SBSSS------------SS??SE-----------EEE?????---??EEEEEGGGTEEEEEEEETTEEEEEEEEEHHHHT???-TT????--HHHH???GGG????????????????---------------????????????????----?????????--------????????????????????---??????????????????????--????- 4BQ7|D PF06535.7_RGM_N_seed 14 222 !Q:0,154|162,221 Q:155,161 ????-????????????????????---------------?????????????????????????--????????????????????????????---------------------???????????---??????????????-????------EEEEEEE??---------------------------------------------------------- 4BQ7|C PF06536.6_Av_adeno_fibre_seed 6 97 !Q:5,5|9,12|21,21|52,56|63,64|71,71|78,78|81,85|93,93|97,97 Q:0,4|6,8|13,20|22,51|57,62|65,70|72,77|79,80|86,92|94,96 EEEEE?TTS????EEEEETTS?EEEEEEEEEEEEETTEEEEEEEEEEETTTS?????SHHHHT??EEEEEE?SBTTTB?TT?????EEESTTB?GGG- 2VTW|A PF06545.6_DUF1116_seed 21 232 !Q:11,12|16,17|19,19|30,30|34,35|41,44|47,47|54,56|81,85|88,88|103,104|108,109|126,129|131,131|135,135|149,149|169,172|174,174|177,178|198,198|201,202|207,210|213,213|215,215|218,219|224,226 Q:0,10|13,15|18,18|20,29|31,33|36,40|45,46|48,53|57,80|86,87|89,102|105,107|110,125|130,130|132,134|136,148|150,168|173,173|175,176|179,197|199,200|203,206|211,212|214,214|216,217|220,223|227,231 SEEEEGGGGTB??STT??B?TTSEEEEEEE-TTT??EEEEE????SS-SSGGGT???HHHHHHHHHHHHTHHHHHHHHHTT----?TT?EEHHHHHHHHHTTT??SSS??HHHHHHHHHHHHHHHH----T-SSS?HHHHHHHHHHHTS?TTTTHHHHHHHHHHHHHHT?---S?TT??BEEEEEEESSEEEEEETTT?TT??EEEE????BS?B?TT??GGGB???EESGG 3CLQ|A PF06550.6_DUF1119_seed 5 298 !Q:5,6|21,32|39,39|58,59|74,74|112,114|138,138|170,215|235,248|273,275|295,297 Q:0,4|7,20|33,38|40,57|60,73|75,111|115,137|139,169|216,234|249,272|276,294 HHHHH--HHHHHHTHHHHGGG???--???????THHHHH-HHHHHHHHHHHHHHHHTT??TTHHHHHHHHHHHH-HHHHHHHHHHHHTTTTSHHHHHHHHHHHHHHHHHHHS???SSHHHHHHHHHHHHHHHHHHHSS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT??????????????????????????????-------------???HHHHHHHHHHHHHHHHTTT??????????????TTSHHHHHHHHHHHHHHHHTTSSS???SHHHHHHHHHHHHHHHHHH??? 4HYD|A PF06552.7_TOM20_plant_seed 6 194 !Q:20,20|23,23|42,42|64,64|67,67|85,87|109,109|112,112|138,144|146,192 Q:0,19|21,22|24,41|43,63|65,66|68,84|88,108|110,111|113,137|145,145|193,193 HHHHHHHHHHHHHHHHHHHH?TT?HHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHHH?TT?HHHHHHHHHHHHHHHHH???HHHHHHHHHHHHHHHHHHHHH?TT?HHHHHHHHHHHTHHHHHHHHHHSSS------?S--------------------------------------------???S 1ZU2|A PF06554.7_Olfactory_mark_seed 4 155 !Q:4,4|7,7|26,29|33,36|46,46|48,49|73,73|76,77|81,83|89,89|92,92|98,98|100,102|104,106|110,110|128,128|138,138|141,142 Q:0,3|5,6|8,25|30,32|37,45|47,47|50,72|74,75|78,80|84,88|90,91|93,97|99,99|103,103|107,109|111,127|129,137|139,140|143,154 EEEE?EE?HHHHHHHHHHHHHHHHTT????TTB????TTEEEEEEE?S??SSEEEEEEEEEESSSEEEEEEEB?TT??TTT???BGGGB?SS?EEEEE?T---T???EEE?HHHHHHHHHHHHHHHHH?SEEEEEEEE?TT??GGGEEEEEEEEE 1F35|A PF06557.6_DUF1122_seed 6 186 !Q:1,3|5,7|12,12|14,14|17,17|30,32|36,37|46,47|53,54|60,62|67,70|90,93|100,100|103,103|114,115|130,131|136,139|143,143|146,147|153,154|173,173|179,181 Q:0,0|4,4|8,11|13,13|15,16|18,29|33,35|38,45|48,52|55,59|63,66|71,89|94,99|101,102|104,113|116,129|132,135|140,142|144,145|148,152|155,172|174,178|182,185 T?-?E---EEEE-E-EE?SSTTEEEEEEEE---TTE--EEEEEEEE??BTTTB??EEEEE???GGGH----HHHTTSHHHHHHHHHHHTT?---SEEEEE?TT?HHHHHHHHTT??GGGSHHHHHHHTTT??EEEE????TTT?SS??EEEEE??SSHHHHHHHHHHHHHHHH-HHHTS???HHHH 2ARH|A PF06559.6_DCD_seed 17 373 !Q:0,9|13,14|32,34|37,37|39,39|42,42|48,48|58,61|64,65|71,71|74,76|81,81|84,84|88,88|91,91|103,104|114,114|131,131|138,138|141,141|155,155|159,159|162,162|173,174|176,177|189,189|192,202|208,209|211,212|223,223|226,228|233,233|238,238|248,249|254,255|259,259|262,263|273,275|285,285|297,298|301,301|306,313|323,323|326,326|333,333|346,372 Q:10,12|15,31|35,36|38,38|40,41|43,47|49,57|62,63|66,70|72,73|77,80|82,83|85,87|89,90|92,102|105,113|115,130|132,137|139,140|142,154|156,158|160,161|163,172|175,175|178,188|190,191|203,207|210,210|213,222|224,225|229,232|234,237|239,247|250,253|256,258|260,261|264,272|276,284|286,296|299,300|302,305|314,322|324,325|327,332|334,345 ?????-????SEE??HHHHHHHHHHTSEEESS???TT?B?SS?EEEEB?SEEEEESSB????TT??HHHHH-HH???EEEE?SS?EEE?TT?EEEEEEEEEEE??TTEEEEEEE?HHHHTTTEEEEEEETT?SSTTEE?TT?EEEEEEEEEESSS?EEE?TT?EEEEEEEEES??B??HHHHHHHHHHS?SB???????????EEEEB??S??TTTTEEEEEE?SS???EETT?GGGS?GGGTEEEEE??SSSE--EEE?TT??EEEEEEEEE???TTEEEEEEE?GGGTTTEEEES??EE?TTTT????????EEEEEEEEE?SS?EEEETT?EEEEEEEEEBSS??????????????????????????? 4A6A|A PF06560.6_GPI_seed 6 190 !Q:9,9|12,12|22,22|25,26|35,37|39,39|42,48|57,59|66,66|68,70|73,73|76,80|83,84|100,101|104,115|122,122|130,130|133,133|140,140|144,144|155,157|159,159|166,167|177,180|187,187 Q:0,8|10,11|13,21|23,24|27,34|38,38|40,41|49,56|60,65|67,67|71,72|74,75|81,82|85,99|102,103|116,121|123,129|131,132|134,139|141,143|145,154|158,158|160,165|168,176|181,186|188,189 EEEGGGGTT?SS?HHHHHHHHH-HT??EEEEEEEE???S?TT?------EEEEEEEE???EETTEE?B???BB?SS-----TT??EEEEEEESSEEEEEE?-TT?----------?EEEEEE?TTEEEEE?TT?EEEEEE?SSS?EEEEEEEETT???B?HHHHHH??SEEEEEETT----EEEEEE?TT 2GC0|A PF06564.7_YhjQ_seed 9 256 !Q:0,1|7,7|30,31|36,36|40,41|45,50|52,52|56,59|66,66|71,71|73,73|82,89|95,97|101,101|114,115|118,118|125,126|128,130|143,143|151,151|165,165|173,173|177,179|190,190|192,200|206,207|219,219|238,248 Q:2,6|8,29|32,35|37,39|42,44|51,51|53,55|60,65|67,70|72,72|74,81|90,94|98,100|102,113|116,117|119,124|127,127|131,142|144,150|152,164|166,172|174,176|180,189|191,191|201,205|208,218|220,237|249,255 ??EEEEE?SSTTSSHHHHHHHHHHHHHHTT??EEEE?SSS??HTT??-???S?HHH----HHTTSS?GGGG?E?SSTTEEEE?----???SHHHH---HHS?GGGHHHHHHTTT--TS?SEEEEE??S---SSSHHHHHHHTT?SEEEEEE?SSHHHHHHHHHTT?EEEEEEE-EEE???HHHHHHHSSS?E---------EEEEE??HHHHHHHHHTS?HHHHSTTSHHHHHHHHHH-----------HHHTTTT 3EA0|A PF06565.7_DUF1126_seed 100 36 !Q:14,27|35,35 Q:0,13|28,34 EEEEETTTTEEEEE?-??????-??-??SSEEEEE? 2Z14|A PF06572.7_DUF1131_seed 8 176 !Q:0,22|32,32|46,47|50,50|81,85|87,88|93,94|97,98|103,104|107,107|113,113|115,116|123,131|136,136|139,139|148,151|153,153|157,159|166,166|175,175 Q:23,31|33,45|48,49|51,80|86,86|89,92|95,96|99,102|105,106|108,112|114,114|117,122|132,135|137,138|140,147|152,152|154,156|160,165|167,174 ------????????---??-???EETTEETTB?TTSBSSHHHHHHH??SS?EEEEEEEEETTEEEEEEEEEETTEEEEEEE??-??B??EEEE??TT??BTTS??TT?BHHHH?S??TTTEEE????-????EEEE?TT?SSEEEEEE????S?TTS???HHHHTT?EEEEEEEE? 2QZB|A PF06573.6_Churchill_seed 7 113 !Q:0,2|10,12|15,17|20,22|27,29|33,34|37,37|44,44|65,66|100,101|104,112 Q:3,9|13,14|18,19|23,26|30,32|35,36|38,43|45,64|67,99|102,103 -??TTBSSSS???TT???SS???TTTB???SSS??SS?EEEEEE-EEEEETTEEEEEEEEEETTT??EEEEEEEEEEEETTEEEEEEEETTTEEEEEEEE??TT???------ 2JOX|A PF06574.7_FAD_syn_seed 62 178 !Q:1,1|4,6|13,14|17,18|33,36|41,41|51,51|58,67|69,69|71,71|73,74|76,76|79,79|92,93|100,100|108,109|123,123|133,133|140,140|154,155|162,166|173,173 Q:0,0|2,3|7,12|15,16|19,32|37,40|42,50|52,57|68,68|70,70|72,72|75,75|77,78|80,91|94,99|101,107|110,122|124,132|134,139|141,153|156,161|167,172|174,177 S?TT???EEEEES??TT??HHHHHHHHHHHHHH----HHHT?EEEEEEESS?HHHHHS----------T-T?S??B-SS?HHHHHHHHHHTT-?SEEEEE?TTTSSSS??HHHHHHHIIIIIT?EEEEEEETT?EESGGG?EEHHHHHHHTTTT--SEEEEE???--EETTEE?SHHH 2X0K|A PF06581.7_p31comet_seed 3 267 !Q:0,46|52,52|55,58|82,82|88,117|138,140|149,149|153,153|161,161|165,172|174,174|193,195|197,201|214,215|224,227|230,230|239,239|241,245|257,257|260,260|263,266 Q:47,51|53,54|59,81|83,87|118,137|141,148|150,152|154,160|162,164|173,173|175,192|196,196|202,213|216,223|228,229|231,238|240,240|246,256|258,259|261,262 --------------------------??--?????????????????EEEEE?SS????HHHHHHHHHHHHHHHHHTTSSSS?HHHHT??????????????????????????????HHHHHHHHHHHHHHHHHHHS???EEEEEESS?SSS?SEEEEEE?TTS????????S?HHHHHHHHHHHHHHTTTT???S?????EEEEEEEEETTS??SSSEEETT????SS?EEEEEEEE?S?????TTTTTTEEEEE?SS?EE???? 2QYF|B PF06585.6_JHBP_seed 92 352 !Q:0,71|73,73|76,85|96,96|104,107|112,114|117,119|125,126|132,138|152,152|156,160|166,169|175,175|186,187|194,194|202,202|206,212|215,216|241,242|244,246|249,251|257,258|267,267|283,284|307,307|309,311|333,346 Q:72,72|74,75|86,95|97,103|108,111|115,116|120,124|127,131|139,151|153,155|161,165|170,174|176,185|188,193|195,201|203,205|213,214|217,240|243,243|247,248|252,256|259,266|268,282|285,306|308,308|312,332|347,351 ------------------------------------------------------------------??????B?TT---------?HHHHHHHHHH-HHHHHTT-?--BTTT---TB???TTEEE??EEEEE-------TTEEEEEEEEEEE?GGG----?EEEEE----EEETT-TTEEEEEEEE--EEEEEE-EEEEEEE-ETT-------EE??EEEEEEEEEEEEEEEEEEEEEEEE-?T---TS?--EEEEE--EEEEEEEE-EEEEEEEEESSBGGG-?HHHHHHHHHHHHHTHHHHHHHH?H---HHHHHHHHHHHHHHHHHHHHS-------------?HHHHB 4G0S|A PF06596.6_PsbX_seed 22 40 !Q:0,1|6,6|17,17|34,39 Q:2,5|7,16|18,33 ??HHHH-HHHHHHHHHH-HHHHHHHHHHHHHHTT?????? 3PRR|X PF06602.9_Myotub-related_seed 24 649 !Q:0,1|6,10|13,22|25,48|51,52|61,118|120,120|122,123|127,134|139,139|145,145|147,147|151,151|160,161|164,166|179,181|187,187|191,192|197,199|201,206|209,209|212,214|217,228|234,234|238,287|294,294|296,296|302,327|329,329|341,345|350,366|374,381|393,411|416,420|423,425|457,459|463,465|470,470|489,489|511,512|518,518|521,584|586,586|589,589|592,594|610,610|614,614|617,617|631,631|637,637|640,640 Q:2,5|11,12|23,24|49,50|53,60|119,119|121,121|124,126|135,138|140,144|146,146|148,150|152,159|162,163|167,178|182,186|188,190|193,196|200,200|207,208|210,211|215,216|229,233|235,237|288,293|295,295|297,301|328,328|330,340|346,349|367,373|382,392|412,415|421,422|426,456|460,462|466,469|471,488|490,510|513,517|519,520|585,585|587,588|590,591|595,609|611,613|615,616|618,630|632,636|638,639|641,648 ??GGGT?????SS?---------GG------------------------GS??HHHHHHHH----------------------------------------------------------T?S--BTT--------EEEE?TTTTS?S?TTS?SSEEEETT??HH---HHHHHHHHBGGG???EEEEE?TTT??EEEE???B----??TT-TT???HH------------HHHHH-HHH--------------------------------------------------HHHSTT?S?EEEEE-------------------------?S?HHHHHHHHHTT?????TTTS-----------------TTEEEEE???---??HHHHHHHHHHH-------------------HHHH-----SS???GGGHHHHHHHHTHHHHHHHHHHHHHHHHHHH---HTS???EEEE?SSSSSHHHHHHHHHHHHH?GGGGSHHHHHHHHHHHTTTTT??HHHHH?TT---------------------------------------------------------------?S?TT?TT???HHHHHHHHHHHHHHH?TTT?SB?HHHHHHHHHHHHH?SSSTT?SS-SHHHHHHT 1M7R|A PF06603.6_UpxZ_seed 13 109 !Q:14,23|43,47|67,67|69,72|74,74|94,94 Q:0,13|24,42|48,66|68,68|73,73|75,93|95,108 HHHHHHHHHHHHHT??????????HHHHHHHHHHHHHHHHHHT?--??SSHHHHHHHHHHHHHHHHH?S??-?S?HHHHHHHHHHHHHTTGGGS?SSHHHHHHHHHHHH 4EPZ|A PF06605.6_Prophage_tail_seed 23 714 !Q:17,26|30,31|33,33|38,42|49,50|53,54|56,60|63,63|71,71|79,79|86,95|99,123|125,125|137,138|141,143|148,149|151,151|153,157|166,166|181,181|194,194|203,204|215,216|225,225|228,229|236,548|550,550|554,554|558,564|569,569|573,573|576,577|579,587|589,591|594,594|597,597|600,600|611,615|617,617|624,642|645,645|654,656|671,672|677,681|687,695|697,697|711,713 Q:0,16|27,29|32,32|34,37|43,48|51,52|55,55|61,62|64,70|72,78|80,85|96,98|124,124|126,136|139,140|144,147|150,150|152,152|158,165|167,180|182,193|195,202|205,214|217,224|226,227|230,235|549,549|551,553|555,557|565,568|570,572|574,575|578,578|588,588|592,593|595,596|598,599|601,610|616,616|618,623|643,644|646,653|657,670|673,676|682,686|696,696|698,710 EEEETTTEEEEEEEEEE??????????SST--T?EEEE-----TTEEEE??EE??B?????EE-EEEEEEB-GGGGGGG?EEEEEE----------EEE-------------------------E?HHHHHHHHHSS??TT--?EEEE??T-T?????EEEEEEEE-EEHHHHHHHHHHHH-TEEEEEETTEEE-EEEGGGSS-?EEEEEEEESS??SSEEEEEE?TT??SEEEEE??-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------B?TTS?BSS-----??EEEE?TTH-HH--H??------?B???EE?TT?SS?TTHHHHHHHH??--?S?EEEEEE??---------???-????TT?EEEEEETT---TTEEEEEEEEEEEE-?TTSS??--?EEEEE??------?S?HHHHHHHHHHHHH??? 3GS9|A PF06607.6_Prokineticin_seed 7 131 !Q:0,35|38,38|45,45|53,53|56,56|59,59|65,65|67,67|70,70|73,73|76,99|102,103|105,107|110,112|114,114|117,117 Q:36,37|39,44|46,52|54,55|57,58|60,64|66,66|68,69|71,72|74,75|100,101|104,104|108,109|113,113|115,116|118,130 --------------------------------????SB?SSGGGT?TTEEEEE?SS?TT?EEEEE?B?TT?EE?TT???---------------------SS??S???SS???B?TT?EEEEEETTEEEEE 2KRA|A PF06613.6_KorB_C_seed 4 60 !Q:0,8|22,22|26,27|41,42|51,51|58,59 Q:9,21|23,25|28,40|43,50|52,57 ?????????EEEEEETTEEEEE?TTB??SSTTEEEEEETTT??EEEEEGGG?EEEEEE?? 1IGQ|A PF06616.6_BsuBI_PstI_RE_seed 22 346 !Q:10,11|17,20|33,34|37,37|40,40|43,47|63,66|89,94|96,96|99,100|102,103|106,106|109,109|114,114|121,129|150,150|178,178|201,202|209,209|211,216|220,220|224,224|233,237|240,243|256,261|267,268|271,274|286,286|289,291|307,308|316,317|330,331|335,337|341,346 Q:0,9|12,16|21,32|35,36|38,39|41,42|48,62|67,88|95,95|97,98|101,101|104,105|107,108|110,113|115,120|130,149|151,177|179,200|203,208|210,210|217,219|221,223|225,232|238,239|244,255|262,266|269,270|275,285|287,288|292,306|309,315|318,329|332,334|338,340 HHHHHHHHTT??GGGSS----HHHHHHHHHHTT??TT?BG-GG?????EEHHHHHHHHHHHSS????GGGHHHHHHHTHHHHHHTTSEE------E?TT??S??TT?TT?EEEE?HHHHHH---------HHHTTSTTHHHHHHHHHTTS?HHHHHHHHHHHHTSEEEEEETTEEEEE?SSTTHHHHHHHHHTHHHHHSTT-?EEEEEE?S------SSS?EEE?HHHHHHTT?????TT????SEEEEETTTTEE------EEEEE??TT????HHHHHHHHHHT?BT---TBEEEEEEEESSHHH--HGGGGGG??SSEEEEETTSTT??EEE-??GGG?????- 2IXS|A PF06619.6_DUF1149_seed 12 133 !Q:0,1|5,7|17,18|26,30|47,53|67,67|70,71|87,89|91,91|96,96|127,132 Q:2,4|8,16|19,25|31,46|54,66|68,69|72,86|90,90|92,95|97,126 ??EEE???EEEEEEEEE??HHHHHHH?????EEEEEEEEEEEETTTT-------EEEEEEEEEEEEE?SS--EEEEEEEEEEEEEET???S?GGGS?HHHHHHHHHHHHHHHHHHHHHHHHHHTTSS?????? 2O2A|A PF06623.6_MHC_I_C_seed 14 29 !Q:0,8|11,11|15,15|18,28 Q:9,10|12,14|16,17 --???????EE?BSS?TT??????????? 4EN2|D PF06627.6_DUF1153_seed 22 91 !Q:0,1|3,6|8,8|13,13|17,17|25,26|29,33|50,50|60,61|75,76|80,81|84,84 Q:2,2|7,7|9,12|14,16|18,24|27,28|34,49|51,59|62,74|77,79|82,83|85,90 ??S????S?SEEE?TTS?EEETTTS??SS?????HHHHHHHHHHHHTTSS?HHHHHHHTT??HHHHHHHHHHTTT??TTS??TT-HHHHHH 2JRT|A PF06628.7_Catalase-rel_seed 343 82 !Q:0,0|4,10|20,20|23,25|41,44|48,48|51,54|62,62|68,68|77,77 Q:1,3|11,19|21,22|26,40|45,47|49,50|55,61|63,67|69,76|78,81 ?GGG?-?-?-?SHHHHHHHH-HS--?HHHHHHHHHHHHHHH----TTS?HH----HHHHHHH-HHHHH?HHHHHHHH-HHHH 1P81|A PF06631.6_DUF1154_seed 11 47 !Q:3,9|16,16|47,47 Q:0,2|10,15|17,46 HHS???????GGGGGG?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH- 4GNK|E PF06632.7_XRCC4_seed 5 380 !Q:0,0|26,26|37,37|40,40|60,61|74,87|93,97|110,110|113,113|122,122|125,125|127,127|217,247|249,303|305,353|355,379 Q:1,25|27,36|38,39|41,59|62,73|88,92|98,109|111,112|114,121|123,124|126,126|128,216|248,248|304,304|354,354 ?EEEEEEEEETTEEEEEEEEEEEESS?GGGEEEEEEE?SS?EEEEEEEHHHHHHHHHHTT??HHHHHHHHHHHH???????-----??EEEEE-----ETTTTEEEEEEE?SS?EEEEEEEE?EE?S?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-------------------------------H-------------------------------------------------------H-------------------------------------------------H??----------------------- 3SR2|A PF06644.6_ATP11_seed 22 361 !Q:0,104|107,118|124,124|132,132|136,137|148,151|153,153|177,178|186,206|217,233|252,252|258,258|266,266|273,273|282,282|287,301|317,323|328,329|347,348|351,352 Q:105,106|119,123|125,131|133,135|138,147|152,152|154,176|179,185|207,216|234,251|253,257|259,265|267,272|274,281|283,286|302,316|324,327|330,346|349,350|353,360 ?????????????????????????????----??????????????--?????????-------????????????????????????????????????????SS----------??HHHHS?HHHHTTS?HHH--HHHHHHHHTT----T?SSEEEEEEETTTTHHHHHHHHHH??EEEEEEE??-----??????????????EEEEEEEEEE-----------------EETTEEEEEEEETTTTTT?HHHHS?SEEEEEE?TTHHHH?EEEEEEEE?TTSS-------------??HHHHHHHHHHHHHHT-------TGGG??SHHHHHHHHHHHHHHHT?-TT??HHHHHHHH 2P4F|A PF06646.6_Mycoplasma_p37_seed 6 379 !Q:12,12|25,27|34,34|37,37|49,49|52,53|58,58|88,89|91,94|96,96|118,121|123,123|127,128|133,144|147,147|150,150|156,157|160,160|166,166|168,168|176,176|191,191|199,199|202,202|204,205|208,208|225,225|228,228|230,232|247,251|258,258|261,262|275,275|278,278|281,281|283,285|287,289|291,303|305,305|313,315|317,319|328,328|347,348|356,357|362,362|364,364|378,378 Q:0,11|13,24|28,33|35,36|38,48|50,51|54,57|59,87|90,90|95,95|97,117|122,122|124,126|129,132|145,146|148,149|151,155|158,159|161,165|167,167|169,175|177,190|192,198|200,201|203,203|206,207|209,224|226,227|229,229|233,246|252,257|259,260|263,274|276,277|279,280|282,282|286,286|290,290|304,304|306,312|316,316|320,327|329,346|349,355|358,361|363,363|365,377 HHHHHHHHHHHH-HHHHTSTTTTTS???EEEEEE-ES?HHHHHHHHHHT?TT??EEEE?HHHHHHHHHHSTTSEEEEEEEEEEEETTB??S????S?SSTTSHHHHHHHHHHHHHTTT----T-GGG??TTTT------------TB?SS?BGGGE--EE-EEEES?B?EEEEEEE?HHHHHHHHHHHHTT?HHHHHHT?EE-E??TT?TTTTHHHHHHHHHHST-TS?S--?HHHHHHHSGGGEEE??---GGGGGG?TT??EEEEETTGGGGS?TT?TT?T---T???T-------------T?EEEEEEE???B???EEEEETTB?HHHHHHHHHHHHHHHHTT??SSGGGGT??EEEE?S?HHHHTHHHHHHHH? 3EKI|A PF06652.7_Methuselah_N_seed 10 210 !Q:0,1|5,5|8,8|14,14|18,18|27,27|39,39|42,43|49,49|55,55|61,61|68,68|71,71|76,77|82,85|88,88|95,98|101,101|105,105|109,109|114,118|128,129|131,132|134,135|138,138|141,142|144,144|150,150|154,164|168,169|176,176|181,181|192,194|198,199|201,202|209,209 Q:2,4|6,7|9,13|15,17|19,26|28,38|40,41|44,48|50,54|56,60|62,67|69,70|72,75|78,81|86,87|89,94|99,100|102,104|106,108|110,113|119,127|130,130|133,133|136,137|139,140|143,143|145,149|151,153|165,167|170,175|177,180|182,191|195,197|200,200|203,208 ??GGG?EE?TTSEE?TTS?EEETTEEE?GGGEEEEEEEE?SS??EEEEE-EEEEE?GGGTS?EEEBSS?SS?EEET--TEEE????HH-HHTTEE---?EE-EEE?TTS?EEEE-----ETTTSSEEE??S??S-?SS?EE??T-TSGGG?EEE-----------ETT??EEETTT-TEEE?TTSEEEEEEE???SSS??E--EEEEEE? 2PZX|A PF06657.8_Cep57_MT_bd_seed 29 82 !Q:0,9|15,17|39,41|48,49 Q:10,14|18,38|42,47|50,81 ??????????HHHHH---HHHHHHHHHHHHHHHHHHHHH---HHHHHT??SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 4L0R|A PF06684.6_AA_synth_seed 55 224 !Q:13,13|20,25|40,41|46,49|51,52|55,55|77,78|82,83|92,92|96,96|105,105|107,156|162,163|166,167|174,184|190,190|196,196|209,223 Q:0,12|14,19|26,39|42,45|50,50|53,54|56,76|79,81|84,91|93,95|97,104|106,106|157,161|164,165|168,173|185,189|191,195|197,208 EEEEEEEEEEEEE-ETTEEE------EEEEEEEEEEEEEE-?TTTT?-??S??HH-HHHHHHHHHHHHHHHHHHHHT??GGG??EEEEEEEE?TTS?HHHHHHHT?S-??????????-------------------------------????????EEEEE??TT??EEEEEB???????????EEEEE?BTTBS?TTEEEEEEEEEE??????------??? 2QTP|A PF06689.8_zf-C4_ClpX_seed 130 45 !Q:0,1|3,3|7,8|15,15|18,18|20,20|22,22|24,27|44,45 Q:2,2|4,6|9,14|16,17|19,19|21,21|23,23|28,43 ??B?TTT??BTTTSS?EE-E?S-S---?EEEHHHHHHHHHHHHT?- 2DS8|A PF06696.6_Strep_SA_rep_seed 32 25 !Q: Q:0,24 HHHHHHHHHHHHHHHHHHHHHHHHH 2WD6|A PF06701.8_MIB_HERC2_seed 9 69 !Q:6,6|9,10|12,13|16,16|19,21|25,25|27,36|59,59|61,61|65,65|68,68 Q:0,5|7,8|11,11|14,15|17,18|22,24|26,26|37,58|60,60|62,64|66,67 TSEEEE?TT??S??TT?SS???EEB?S-------???SSEEEEEETTTEEEEEEBSTTS?B?EEE?TT? 3DKM|A PF06702.7_DUF1193_seed 19 334 !Q:3,3|6,21|25,28|31,32|37,37|40,42|54,57|62,62|68,68|71,75|79,81|86,86|117,135|140,160|166,167|172,180|182,226|229,231|234,234|236,237|240,242|247,248|255,259|274,274|289,291|294,296|298,298|324,325|331,331 Q:0,2|4,5|22,24|29,30|33,36|38,39|43,53|58,61|63,67|69,70|76,78|82,85|87,116|136,139|161,165|168,171|181,181|227,228|232,233|235,235|238,239|243,246|249,254|260,273|275,288|292,293|297,297|299,323|326,330|332,333 EEE?TT--------------??EEE????SS??SSTT?EE?--SSSEEEEEEEE????TTTS?EEEEE?TT?????SSS???HHHH?TTHHHHHTTTSHHHHEESHHHHHHHHHHHH-------------------HHHT---------??-------???EEEEE??SSSS------???E---------------------------------------------EB???TT?S??SS???TTTT--HHHHHH-????HHHHHHHHHHHHST-THHHHHHHHHHTTS---TT???S?TTHHHHHHHHHHHHHHHHHHHHHHH?-HHHHS?SS 4KQA|A PF06714.6_Gp5_OB_seed 8 160 !Q:3,3|5,6|8,9|13,15|20,20|25,27|30,32|39,39|41,44|47,47|54,54|59,60|68,69|72,72|74,76|83,83|87,88|90,92|100,100|107,109|115,117|123,133|138,139|143,146|148,148|152,155|158,158 Q:0,2|4,4|7,7|10,12|16,19|21,24|28,29|33,38|40,40|45,46|48,53|55,58|61,67|70,71|73,73|77,82|84,86|89,89|93,99|101,106|110,114|118,122|134,137|140,142|147,147|149,151|156,157|159,159 TTS?S??S??SSB???GGGS?EEEE???TT???BTTBSS?S????TT?EEEEEE?STTS??EEEEEEE??EE?S???TTSSSS?SSS??S---SSSEESS?HHHHBH---HHHHT?--HHHHH-----------HHTS??EEE????S?STT????SS?S 1PDL|A PF06715.7_Gp5_C_seed 89 26 !Q:1,7|10,15|18,24 Q:0,0|8,9|16,17|25,25 S???-???SS??????SS-??????S 1PDL|A PF06720.6_Phi-29_GP16_7_seed 2 130 !Q:0,68|83,86|97,98|122,125|128,129 Q:69,82|87,96|99,121|126,127 ------------------------------------------------------------?????????HHHHHHHHHHHHTT????HHHHHHHHHH??SSHHHHHHHHHHHHHHHHHHHHS????SS?? 2C5R|A PF06722.7_DUF1205_seed 33 119 !Q:2,2|4,4|9,22|25,26|28,34|37,42|44,45|50,55|58,59|65,80|93,93|100,102|109,110|113,114 Q:0,1|3,3|5,8|23,24|27,27|35,36|43,43|46,49|56,57|60,64|81,92|94,99|103,108|111,112|115,118 EE?S?GGGS?---?---??--??EE--E???????SS--????G--GGSS?----?SS?-EEEEE???????---??????STTTTHHHHHTS-SSEEEE???TTTTSS?-SS??SSEE 4AMG|A PF06723.8_MreB_Mbl_seed 31 341 !Q:1,1|8,8|15,16|30,30|37,41|43,44|58,60|67,68|94,95|97,98|100,100|102,103|110,110|113,114|130,130|148,149|155,155|162,162|165,165|184,184|202,202|205,206|218,218|220,220|222,223|229,230|242,243|269,269|278,278|289,289|313,313|317,317|334,334 Q:0,0|2,7|9,14|17,29|31,36|42,42|45,57|61,66|69,93|96,96|99,99|101,101|104,109|111,112|115,129|131,147|150,154|156,161|163,164|166,183|185,201|203,204|207,217|219,219|221,221|224,228|231,241|244,268|270,277|279,288|290,312|314,316|318,333|335,340 S?EEEEEE?SSEEEE--EETTTEEEEEEES?EEEETT-----T??EEEESHHHHTTTT???TTEEEE??EETTEESSHHHHHHHHHHHHHHHHT--S??S-S??EEEEEE?TT??HHHHHHHHHHHHHTT?SEEEEEEHHHHHHHHTT??TTSSS?EEEEEE?SS?EEEEEEETTEEEEEEEES?SHHHHHHHHHHHHHHHH?EE??HHHHHHHHHHH?B?S??HHHHH-?EEEEEEEETTT??EEEEEEEHHHHHHHTHHHHHHHHHH-HHHHHHHS?HHHHHHHHHH?EEEESGGGGSBTHHHHHHHHHSS?EEE?SSTTTHHHHHHHHGGG?HHHHTT 1NGH|A PF06725.6_3D_seed 41 83 !Q:4,5|10,10|13,13|20,21|25,25|29,29|36,36|45,46|49,50|53,53|70,70|73,73 Q:0,3|6,9|11,12|14,19|22,24|26,28|30,35|37,44|47,48|51,52|54,69|71,72|74,82 SEEE??TTTS?TT?EEEEEE--EEE?SSS?EEEEEE-EEEEEEEE??TT??TT-EEEEEEEESHHHHHHH?SS?EEEEEEEEE 2G6G|A PF06733.10_DEAD_2_seed 33 235 !Q:23,40|44,47|52,52|59,61|63,64|66,67|86,106|113,113|117,120|123,123|127,129|137,139|146,151|158,159|165,165|172,172|184,184|194,195|199,200|221,223|226,226 Q:0,22|41,43|48,51|53,58|62,62|65,65|68,85|107,112|114,116|121,122|124,126|130,136|140,145|152,157|160,164|166,171|173,183|185,193|196,198|201,220|224,225|227,234 EEESSHHHHHHHHHHHHHHHHHS?---------------??EEE-???HHHH?SSHHHH???S--S??HHHHHHHHHHHHHHHHTT--------------------?TTSSTT?SGG----GG?HHH---HHHHHHH???HHHHHH------HHHHTT??HHHHH-HHHGGG?SEEEEEHHHHT?HHHHHHHHH--HHT??GGGEEEEETTGGGHHHHHHH---HH?EEEEHHHH 3CRV|A PF06737.9_Transglycosylas_seed 18 80 !Q:0,0|17,17|19,19|21,23|28,28|32,34|48,48|50,50|56,56|77,77 Q:1,16|18,18|20,20|24,27|29,31|35,47|49,49|51,55|57,76|78,79 ?TTHHHHHHHHHHHTSS?T-T???SSSB?TTT-??BHHHHHHTTGGGT?S-STTTS?HHHHHHHHHHHHHHHSSTTS?HH 1XSF|A PF06742.6_DUF1214_seed 331 264 !Q:2,2|8,8|11,14|16,17|23,23|25,30|35,40|44,49|52,53|55,55|57,57|61,68|70,70|77,78|80,83|88,88|90,93|95,101|103,105|107,109|111,123|126,127|129,129|132,138|140,159|163,164|171,171|174,178|181,196|199,207|209,210|212,230|233,240|242,248|258,259|261,262 Q:0,1|3,7|9,10|15,15|18,22|24,24|31,34|41,43|50,51|54,54|56,56|58,60|69,69|71,76|79,79|84,87|89,89|94,94|102,102|106,106|110,110|124,125|128,128|130,131|139,139|160,162|165,170|172,173|179,180|197,198|208,208|211,211|231,232|241,241|249,257|260,260|263,263 TT-SSEEE-EE----E?-BBTTS?B-----?BTTS----?-EEE------EE?-S-S?SEE--------E-EEEEEE--E----ETTT?S----B???----S---S???E-------------EE--T-TS----???B-------------------?TTS-?EEEEES-SS?---?TT-?--------------TT---------S--B?------------??---?TT---?----B-------EEEEEEEEE--E-?H 2P3Y|A PF06745.8_KaiC_seed 26 279 !Q:1,4|12,12|14,26|33,33|40,40|57,57|62,63|72,72|74,77|86,86|90,92|106,106|112,118|120,120|122,122|124,125|144,147|158,159|163,163|167,167|180,180|185,185|193,209|213,213|229,240|255,258|260,260|268,268|274,274|277,278 Q:0,0|5,11|13,13|27,32|34,39|41,56|58,61|64,71|73,73|78,85|87,89|93,105|107,111|119,119|121,121|123,123|126,143|148,157|160,162|164,166|168,179|181,184|186,192|210,212|214,228|241,254|259,259|261,267|269,273|275,276 E????TTHHHHT-T-------------TSEETT?EEEEEE?TTSSHHHHHHHHHHHH-HHTT??EEEEESSS?H----HHHHHHHH-TTT???HHHHHHTSEEEEE?STTTT???????S?B?S??SSHHHHHHHHHHHHHHHT?--?EEEEETSGGG--TTT?GGG-HHHHHHHHHHHH-HHTT?EEEEEEE???-----?????????HHH-HSSEEEEEEEEEETT------------EEEEEEEEEEETTS????B?EEEEEET-TEEEE?TT?? 4B32|A PF06747.8_CHCH_seed 53 41 !Q:15,19|36,36 Q:0,14|20,35|37,40 THHHHHHHHHHHHHH??---SSTTTTTHHHHHHHHH-HHHH 2K3J|A PF06748.7_DUF1217_seed 53 401 !Q:9,9|20,22|28,28|35,43|46,46|56,56|60,60|62,65|69,116|125,242|262,262|276,284|287,288|290,323|332,344|356,369|381,388|394,395 Q:0,8|10,19|23,27|29,34|44,45|47,55|57,59|61,61|66,68|117,124|243,261|263,275|285,286|289,289|324,331|345,355|370,380|389,393|396,400 HTTGGGSTT?HHHHHHHHHH--?SSSTT?GGGGSS---------ST-HHHHHHHHT?HHH-H----GGG------------------------------------------------TTSSTTTT----------------------------------------------------------------------------------------------------------------------HHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHS---------TT??S----------------------------------HHHHHTSH-------------HHHHHHHTTTT??-???????---?TTHHHHHHHSS-------?TTTTT?-TTHHH 2O8S|A PF06751.6_EutB_seed 12 453 !Q:3,3|5,5|15,17|25,25|27,27|43,43|52,52|55,55|59,59|69,70|80,80|94,98|109,110|121,122|133,136|144,145|149,149|151,151|154,157|160,161|177,178|185,186|188,189|210,211|213,213|217,217|219,219|231,233|235,235|240,241|252,253|268,268|270,270|272,273|275,276|281,282|284,301|317,317|327,335|356,356|364,370|386,387|394,394|397,397|404,406|419,419|422,422|436,436|438,438|443,443|448,448 Q:0,2|4,4|6,14|18,24|26,26|28,42|44,51|53,54|56,58|60,68|71,79|81,93|99,108|111,120|123,132|137,143|146,148|150,150|152,153|158,159|162,176|179,184|187,187|190,209|212,212|214,216|218,218|220,230|234,234|236,239|242,251|254,267|269,269|271,271|274,274|277,280|283,283|302,316|318,326|336,355|357,363|371,385|388,393|395,396|398,403|407,418|420,421|423,435|437,437|439,442|444,447|449,452 EEE?S?HHHHHHHTS???HHHHHHT?S?SSHHHHHHHHHHHHH?BHHHHHHS?SS?TTT?HHHHHHHHT??HHHHHHHTT?BHHHHHHHHHSTT??---HHHHHHHHTT??HHHHHHHHHT??HHHHHHHHHS????EESSSEE??TTB?B?EE????TT??HHHHHHHHHHHHHTT??SSEEEE??S??SHHHHHHHHHHHHHHHHHTT??S?EEE?S?HHHHHHHHHTT???S?EEEE??SSHHHHHHHT??HHHHHHHHHHHHHH?S-S??S??EEEE??S???????????-----??HHHHHHHHHHHHHHT?EEEEEEEEE?????????THHHHHHHHHHHHHHHHHTS?EEEEEEE???????HHHHHHHHHHHHHTT??BEEEEE?SS?HHHHHH???HHHHHHHHHHHT?BS?HHHHHHHHHHTSE-E-TTEE?TTTT?GGGG 3ABQ|A PF06757.8_Ins_allergen_rp_seed 38 225 !Q:0,0|12,12|14,14|20,23|33,33|58,58|60,60|73,74|76,77|83,89|92,133|135,135|149,149|164,164|166,166|190,194|208,208|210,211|213,215 Q:1,11|13,13|15,19|24,32|34,57|59,59|61,72|75,75|78,82|90,91|134,134|136,148|150,163|165,165|167,189|195,207|209,209|212,212|216,224 ?HHHHHHHHHHH-S?HHHHH----HHHHHHHHH?HHHHHHHHHHTSHHHHHHHHHHHH?H-HHHHHHHHHHHT--T??HHHHH-------HT???????---?????-----------??????-------???S?HHHHHHHHHHHHS?HHHHHHHHHHHHHH?H-HHHHHHHHHHSHHHHHHHHHHHT?----HHHHHHHHHHHTT-T??H---HHHHHHHHH 4JRB|A PF06764.6_DUF1223_seed 72 248 !Q:6,6|9,9|12,12|22,24|29,41|43,43|52,52|56,56|61,62|65,66|81,82|84,84|86,88|104,104|119,119|121,121|123,124|126,126|131,131|133,133|135,135|137,137|144,146|149,149|151,160|170,170|176,184|199,201|205,205|207,207|209,209|215,215|217,220|230,239 Q:0,5|7,8|10,11|13,21|25,28|42,42|44,51|53,55|57,60|63,64|67,80|83,83|85,85|89,103|105,118|120,120|122,122|125,125|127,130|132,132|134,134|136,136|138,143|147,148|150,150|161,169|171,175|185,198|202,204|206,206|208,208|210,214|216,216|221,229|240,247 EEEEEE?TT?TT?HHHHHHHHH---HHHH-------------T-SSEEEEEE?STT?SSSS??TT??HHHHHHHHHHHHHT--T?S???SSEEEETTTEEEETT?HHHHHHHHHHHHHT-T?S??S?EEEE-E?S-S-SEEEEE???SS?E----------EEEEEEEEE-EEEEE?????????EEEEEEEEEEEEEE---EEE?S-S?EEEEE?H----HHHHHHTTE----------EEEEEEEE 2AXO|A PF06766.6_Hydrophobin_2_seed 45 71 !Q:0,0|2,3|6,6|9,9|11,11|29,30|33,35|48,48|50,50|57,57|59,59|61,61|70,70 Q:1,1|4,5|7,8|10,10|12,28|31,32|36,47|49,49|51,56|58,58|60,60|62,69 ?S?-SS-TT?E-EEEEEEEEBTTEEEEEE??SS???SHHHHHHHHHTT-T?EEEEES?S-S?EEEEEEEE? 1R2M|A PF06767.6_Sif_seed 4 337 !Q:0,23|37,38|58,60|76,76|87,87|91,91|94,94|101,101|105,105|114,114|132,135|137,138|140,140|143,143|167,167|172,172|177,177|192,192|221,221|224,226|243,247|250,251|254,256|268,268|279,279|303,305|327,336 Q:24,36|39,57|61,75|77,86|88,90|92,93|95,100|102,104|106,113|115,131|136,136|139,139|141,142|144,166|168,171|173,176|178,191|193,220|222,223|227,242|248,249|252,253|257,267|269,278|280,302|306,326 ????????????????????????HHHHHHHHTTTTT??HHHHHHHHHHHHHHHSSSS???HHHHHHHHHHHHHHS?GGGGTTEEEE?GGG?TT?EEEEEE?TTS?SEEEEEEE?SSEEEEEETTEEEEEEE????S??S?SS?EEEEEEEEETTTTEEEEEEEEEE?SSSS?EEEE?HHHHHHHHHHHTSS?SHHHHHHHHHHHHHHHHHHHHHHHHHHT?SS???HHHHHHHHHHHHHHHT?????SS??SS???HHHHHHHHHHS?TTTHHHHTSS?SSSHHHHHHHHHHHHHHHHHHHH???HHHHHHHHHHHHHHHHGGGGT????-????? 3HW2|A PF06769.8_Plasmid_Txe_seed 13 85 !Q:1,1|15,15|33,33|40,41|44,45|51,51|60,60|67,71|82,84 Q:0,0|2,14|16,32|34,39|42,43|46,50|52,59|61,66|72,81 E?HHHHHHHHHHHTT?HHHHHHHHHHHHHHHHS-TTSSTT??EE??GGGTT?EEEESSSS?EEEEEE?----SSEEEEEESS??? 2A6S|A PF06776.7_IalB_seed 84 187 !Q:8,29|40,40|42,43|53,53|56,62|64,64|67,68|74,74|78,78|82,82|89,94|98,98|102,103|105,107|112,116|125,125|127,127|136,138|140,140|154,161|163,163|171,175 Q:0,7|30,39|41,41|44,52|54,55|63,63|65,66|69,73|75,77|79,81|83,88|95,97|99,101|104,104|108,111|117,124|126,126|128,135|139,139|141,153|162,162|164,170|176,186 ETTEEEEE????---???-----------?EEEEEEEEBT-T??EEEEEEEEE?TT-------S?EE--EEEEE?SSB?TTS?EEEEET------TSS?EEE--E???EEET-----TEEEEEEE-E?HHHHHHHH---H?SEEEEEEEBSSTT?------?E-EEEEEEE?----TTHHHHHHHHH 3DTD|A PF06778.7_Chlor_dismutase_seed 15 220 !Q:13,13|26,26|28,28|35,35|39,39|41,42|67,67|85,93|97,97|101,104|113,120|131,131|142,142|164,166|173,173|189,189|212,212|214,216 Q:0,12|14,25|27,27|29,34|36,38|40,40|43,66|68,84|94,96|98,100|105,112|121,130|132,141|143,163|167,172|174,188|190,211|213,213|217,219 HHHHHHHHHHHHH-HHHHHHHHHTTS?E-EEEEEE?SSS?S--EEEEEEESSHHHHHHHHHHHHHST-GGGGEEEEEEEEEEEEE??????---SSS?GGG---?HHHHHHHS????--??SEEEEEEEEE?EETTEEGGGS?HHHHHHHHHHHHHHHHTTTTT--?EEEEEE?TTTSSSSEEEEEEES?THHHHHHHHHHHTSHHHHHHEE-E???EEE 3Q09|A PF06794.7_UPF0270_seed 53 82 !Q:2,4|7,9|12,12|25,27|29,40|62,62|66,72 Q:0,1|5,6|10,11|13,24|28,28|41,61|63,65|73,81 EE-??GG---GS?HHHHHHHHHHHH---H????????-???HHHHHHHHHHHHHTTSEEEEE?TTT?-----?EEEEEGGGS 1Y0N|A PF06804.6_Lipoprotein_18_seed 6 314 !Q:5,16|19,23|25,25|29,36|38,39|45,45|47,54|58,58|63,64|74,82|95,96|114,116|119,119|122,122|134,134|150,150|155,157|180,313 Q:0,4|17,18|24,24|26,28|37,37|40,44|46,46|55,57|59,62|65,73|83,94|97,113|117,118|120,121|123,133|135,149|151,154|158,179 GGGGS?????????---TT?????S?STT????????S??GGGSB?S????????STT?EEEE--ETTEEEEEE??????-??HHHHHHHHHHTT??EEEEETTTTEEEEEEEE???TT?SS?EEEEEEEEEEE?SSSEEEEEEEEEEEE-TTEE???HHHHHHHHHHHHHHHHHHHHTT???????????????????????????????????????????????????????????????????????????????????---???????????????????????????????????????????????? 2LAF|A PF06806.7_DUF1233_seed 13 80 !Q:0,12|15,15|24,26|38,39|48,48|53,55|58,58|73,77 Q:13,14|16,23|27,37|40,47|49,52|56,57|59,72|78,79 ??-------????EE?HHHHHHHH???HHHHHHHHTTT??BTTTEEEE?SSSS-??TT?EEEEEHHHHHHHHH-----HH 2KVV|A PF06807.9_Clp1_seed 16 293 !Q:0,4|7,7|19,24|30,32|35,35|49,49|51,70|77,79|82,113|131,133|137,137|139,143|153,170|175,186|188,188|194,195|197,197|201,204|218,228|230,230|233,234|238,244|247,247|273,278|280,280|286,289|292,293 Q:5,6|8,18|25,29|33,34|36,48|50,50|71,76|80,81|114,130|134,136|138,138|144,152|171,174|187,187|189,193|196,196|198,200|205,217|229,229|231,232|235,237|245,246|248,272|279,279|281,285|290,291 ----?SS?HHHHHHHHHTT??----EEEEE?-?SS?THHHHHHHHHHHH?G--------------------GGEEEE???TT??---------------------------???HHHHHHHHHHHHHHHHH-??TTT?B---??EEEEEESTT?----------------?EEEE--------??--S-TTTSS??S?EEE????HHHHTTEEEEEES-----------S?TT??HHT-------TS?EEEEEEEEEEETTTTEEEEEESSSS?-?-??S?EEEEE----EE?- 2NPI|A PF06815.8_RVT_connect_seed 47 110 !Q:0,3|7,8|15,15|27,27|32,33|39,40|42,43|48,49|72,74|81,81|85,86|92,92|96,98|101,103|107,108 Q:4,6|9,14|16,26|28,31|34,38|41,41|44,47|50,71|75,80|82,84|87,91|93,95|99,100|104,106|109,109 ????SSS??EEEEEE?SSSBEEEEEEE-ETTE--EEEEE??B??SSTT??HHHHHHHHHHHHHHHHHHHTSS??-EEEESB?HHH--HHHHH-HHH???SS???EEE??S 1REV|A PF06816.8_NOD_seed 26 60 !Q:0,2|4,4|14,14|16,16|21,22|44,44|46,46|50,50|52,52|56,56|59,59 Q:3,3|5,13|15,15|17,20|23,43|45,45|47,49|51,51|53,55|57,58 ???B?BSEEEEEES-S?HHHH--HHTHHHHHHHHHHHHTSEEEE?B?TTS?B?EEE?TT? 3ETO|A PF06817.9_RVT_thumb_seed 41 76 !Q:2,2|4,11|13,14|16,16|33,33|36,36|40,43|53,56|59,59|61,64 Q:0,1|3,3|12,12|15,15|17,32|34,35|37,39|44,52|57,58|60,60|65,75 EE?B????????S--S?BHHHHHHHHHHHHHHH-TT-STT-???HHHHHTTTT-???TT?B????HHHHHHHHHHH 1REV|A PF06821.8_Ser_hydrolase_seed 24 206 !Q:4,5|8,10|12,12|23,23|27,27|30,32|34,38|41,42|57,57|60,67|85,89|93,93|95,96|106,108|111,129|133,133|138,138|141,142|145,145|147,151|156,156|163,163|176,176|181,182|184,184|193,193|196,196 Q:0,3|6,7|11,11|13,22|24,26|28,29|33,33|39,40|43,56|58,59|68,84|90,92|94,94|97,105|109,110|130,132|134,137|139,140|143,144|146,146|152,155|157,162|164,175|177,180|183,183|185,192|194,195|197,205 EEEE??TT???T-TSHHHHHHHH?TTS-EE???S??---SS??HHHHHHHHHHHHHT?SS?-------EEEEEETHHHHHHHHHH-----HTT?S--SEEEEEEES???GG-------------------GGT?TTTS?SS??SS?E-----EEEE?SSBTTB?HHHHHHHHHHHT?EEEE??S?TTSSGGGT?SS?HHHHHHHHH 3BDV|A PF06824.6_DUF1237_seed 51 688 !Q:0,0|8,8|17,25|34,78|82,82|88,89|93,93|114,114|116,126|146,146|149,149|153,153|156,164|167,167|171,171|176,204|206,206|211,214|233,244|247,247|251,251|268,301|306,307|309,311|313,314|317,317|322,322|328,328|330,334|337,338|340,340|343,343|347,347|349,349|357,357|373,375|378,379|383,385|388,403|427,436|438,438|446,446|450,450|454,454|457,460|465,465|471,471|477,478|481,481|483,570|584,584|591,591|594,594|598,599|603,603|608,608|619,634|655,656|665,666|671,671|673,673 Q:1,7|9,16|26,33|79,81|83,87|90,92|94,113|115,115|127,145|147,148|150,152|154,155|165,166|168,170|172,175|205,205|207,210|215,232|245,246|248,250|252,267|302,305|308,308|312,312|315,316|318,321|323,327|329,329|335,336|339,339|341,342|344,346|348,348|350,356|358,372|376,377|380,382|386,387|404,426|437,437|439,445|447,449|451,453|455,456|461,464|466,470|472,476|479,480|482,482|571,583|585,590|592,593|595,597|600,602|604,607|609,618|635,654|657,664|667,670|672,672|674,687 ?HHHHHHH-HHHTTHHH---------HHTEEEEE?--------------------------------------------TTS?EEEEE??BSS?SEEHHHHHHHTGGGGGGGGG?H-----------HHHHHHHHHHHHHHHHHHH?TT?SEE?SS-------??TT?TTT-TSBS---------?-??----------------T-TEEE????HHHHHHHHHHHHHHHHHH-???--------TT?SHH-HHHHHHHHHHHHHHTT?---------------------------------SSSS-?S???B??BS?GGGS?HHHHT?S????-SS??B?SB?TTS?B?SSSEEHH-HHHHHHHHHHHHHHH---HH--HTS??-HH----------------HHHHHHHHHHHHHHHHHHHSEEE----------E-TTTEEEE?SEE?SSS?EE????SSSS?STTHH-HHTSS?-TT?H----------------------------------------------------------------------------------------HHHHHHHHHTSTT-STTEEE?SS?EEE??TTT?TTEE?HHHHHHHHHT?-------------??HHHHHHHHHHHHHTSTTSSS??SEEETTEE--EEEE?S?BHHHHHHHHHHHHH 3P2C|A PF06825.7_HSBP1_seed 20 79 !Q:33,55|63,78 Q:0,32|56,62 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----------------------HHHHHTT????------------ 3CI9|A PF06827.9_zf-FPG_IleRS_seed 143 35 !Q:3,3|6,7|9,10|12,13|19,20|28,28|32,34 Q:0,2|4,5|8,8|11,11|14,18|21,27|29,31 TSB?TT--T??B-?EEEEE--TTEEEEE?TTT?-? 3GP1|A PF06831.9_H2TH_seed 19 128 !Q:0,2|6,13|16,18|20,34|44,57|66,66|73,74|87,88|96,97|121,121|126,126 Q:3,5|14,15|19,19|35,43|58,65|67,72|75,86|89,95|98,120|122,125|127,127 ???BTT--------TS???H---------------HHHHHHHTT---?----?-----SBHHHHHH?TTTSBS??HHHHHHHHHHHT??TTSBGGG??HHHHHHHHHHHHHHHHHHHHTTT?GGGS?T 3GP1|A PF06833.6_MdcE_seed 9 258 !Q:3,3|7,12|29,29|40,44|51,51|53,53|58,58|69,73|78,79|87,88|90,97|114,115|117,120|141,141|147,147|149,150|152,152|158,158|164,186|196,197|200,204|219,239|241,257 Q:0,2|4,6|13,28|30,39|45,50|52,52|54,57|59,68|74,77|80,86|89,89|98,113|116,116|121,140|142,146|148,148|151,151|153,157|159,163|187,195|198,199|205,218|240,240 HHS?TTS??----EEESTTSSEEEEEEEE-TTEEEEEEEE-?---TTTGGG?B?HHHH-HHHHHHHHHH-----HHHT??EEEEEEE??B????????HHHHHHHHHHHHHHHH??S---?EEEEEEEEEEHHHHHHTGGT?SEEEE?T--T?EEESS?HHHHH???????????????????????HHHHHHHTS??EE??---GGGHHHHHHHHHHH---------------------S????????--------- 2F9Y|A PF06835.8_LptC_seed 64 231 !Q:0,58|63,63|71,71|76,84|90,90|96,96|99,117|124,124|130,130|132,132|147,147|151,151|153,166|182,182|197,199|223,225|228,228|230,230 Q:59,62|64,70|72,75|85,89|91,95|97,98|118,123|125,129|131,131|133,146|148,150|152,152|167,181|183,196|200,222|226,227|229,229 ------------??????????-----?????????????????????????????-??EEEE?SSEEEET-TTTE---------EEEES?EEEEE?TT??-----------------EEEEEE?SEEEE?T-TSEEEEEEEEEEEE?SSS?S--------------EEEEEEEEEEEETTT?EEEEEEEEEEEESS?--EEEEEEEEEETTTTEEEEEEEEE---ET-T? 4B54|A PF06838.6_Met_gamma_lyase_seed 14 408 !Q:38,39|44,47|50,51|53,53|69,69|73,74|79,79|93,94|97,97|102,102|106,107|119,120|124,124|130,130|135,136|138,138|144,144|152,155|165,165|167,167|173,176|191,191|194,194|200,200|203,203|209,210|216,216|232,232|235,235|241,241|254,254|261,261|263,265|267,267|301,302|306,306|310,311|315,316|320,322|344,347|350,350|361,363|368,368|372,372|379,379|388,389|407,407 Q:0,37|40,43|48,49|52,52|54,68|70,72|75,78|80,92|95,96|98,101|103,105|108,118|121,123|125,129|131,134|137,137|139,143|145,151|156,164|166,166|168,172|177,190|192,193|195,199|201,202|204,208|211,215|217,231|233,234|236,240|242,253|255,260|262,262|266,266|268,300|303,305|307,309|312,314|317,319|323,343|348,349|351,360|364,367|369,371|373,378|380,387|390,406 SHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHTT??GGGS????TT??S?HHHHHHHHHHHHHTT?SEE??BTTS?SHHHHHHHHHHTT??TT?EEEE?SSS??TTHHHHTTSSS?-SSS?SGGGT?EEEE??B?TTSSB?HHHHHHH??--TTEEEEEEE?S?TTSSS????HHHHHHHHHHHHHH?TT?EEEEE?TT?TTSSS??GGGTT?SEEEEETTSGGGTTT?SS?EEEEE?HHHHHHHHHHHS?TTTTTS?S???S?SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT??EES?TTS??SSS??EEE???HHHHHHHHHHHHHTSSSSTTS????EE?TTSSSEEEEE???SSSS?TTS?EEEEES?TTTEEEEE??SSHHHHHHHHHHHHHHT? 3GWP|A PF06840.6_DUF1241_seed 6 178 !Q:0,7|11,18|34,34|36,36|39,43|75,76|93,94|96,99|101,107|163,168|172,172 Q:8,10|19,33|35,35|37,38|44,74|77,92|95,95|100,100|108,162|169,171|173,177 ????????TTH--------HHHHTHHHHHHTTTT-T?HH-----HHHHHHHHHHHHHHHSTTHHHHHHHHHHTTH--HHHHHHHHHHHHHTTS??T----T???????HHHHHHHHHHHHHHHHHHTGGGTTTSHHHHHHHHHHHHHHHHHHHHHHHHHGGGS?-----GGG?HHHHH 3RQG|A PF06844.6_DUF1244_seed 69 68 !Q:1,1|11,12|29,32|44,44|50,67 Q:0,0|2,10|13,28|33,43|45,49 S?HHHHHHHHS??HHHHHHHHHHHHHHTT????HHHHHHHHHSS?HHHHT?????????????????? 3FYB|A PF06847.6_Arc_PepC_II_seed 21 120 !Q:10,10|17,36|43,44|52,62|64,64|67,71|73,75|77,80|82,82|84,88|90,91|95,99|118,118 Q:0,9|11,16|37,42|45,51|63,63|65,66|72,72|76,76|81,81|83,83|89,89|92,94|100,117|119,119 SHHHHHHHHH?EEEEHH--------------------HHHHTT??EEEETTE-----------E?SS?????T---T????S?S----?E--EEE?????THHHHHHHHHHHHHHTTH-H 3S0X|A PF06849.7_DUF1246_seed 43 141 !Q:20,21|27,27|31,32|40,54|60,60|83,84|93,93|101,102|104,104|108,108|117,117|124,126|133,137 Q:0,19|22,26|28,30|33,39|55,59|61,82|85,92|94,100|103,103|105,107|109,116|118,123|127,132|138,140 EEEESSTTHHHHHHHHHHTT??EEEEE?TTS-?HHHHHTT-------------??SEEEE?SSGGGGGSHHHHHHHHHTTEEE??BHHHHHHH?HHHHHHT??S?BBS?GGGGHHHH?HHHHHH---HHHHTT?????EES 2R7M|A PF06855.7_DUF1250_seed 47 47 !Q:7,7|11,11|14,16|27,27|47,47 Q:0,6|8,10|12,13|17,26|28,46 HHHHHHT?TTS?TT???HHHHHHHHHT-SHHHHTTHHHHHHHHHHHH- 2FJ6|A PF06858.9_NOG1_seed 25 61 !Q:13,13|21,21|24,24|29,32|51,51|57,58 Q:0,12|14,20|22,23|25,28|33,50|52,56|59,60 HHHHHHHHGGGGT?SEEEEEE?TT?TTSS---?HHHHHHHHHHHHHHTTTS?EEEEE??TT 2E87|A PF06859.7_Bin3_seed 5 112 !Q:0,0|9,9|43,45|56,56|66,69|83,85|89,89|91,106|111,111 Q:1,8|10,42|46,55|57,65|70,82|86,88|90,90|107,110 ?EEEEEEES?HHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEE???HHHHHTTTTS?HHHHHHHHH????GGGHHHHHTSTTT???EEE-E???????????-????EEEE? 3G07|A PF06863.7_DUF1254_seed 340 258 !Q:4,27|39,40|44,44|50,55|58,59|61,61|71,71|74,94|98,100|105,110|114,115|118,118|121,122|124,124|129,145|147,172|175,199|202,203|219,226|228,228|232,233|237,237|239,243|246,246|251,251|253,254 Q:0,3|28,38|41,43|45,49|56,57|60,60|62,70|72,73|95,97|101,104|111,113|116,117|119,120|123,123|125,128|146,146|173,174|200,201|204,218|227,227|229,231|234,236|238,238|244,245|247,250|252,252|255,257 SSSB????-???????--?????---??SSEEEEEEEEE?-SSS?EEEEE?-?-??TT??E-EEEEEETTS?EE---------------------EEE---EHHH------HTT??EE-EE--E-EETT?--------------?-S?----??-------------------TT??-----------------------EE--EEESBSEEEEEEEEE?------?S-HHH--HHH-H-----HH-HHTT?E--EEE 2P3Y|A PF06865.6_DUF1255_seed 85 107 !Q:0,1|21,21|30,30|34,38|46,46|63,63|65,69|71,71|78,78|83,83|94,96|98,98|105,106 Q:2,20|22,29|31,33|39,45|47,62|64,64|70,70|72,77|79,82|84,93|97,97|99,104 ??EEEEEGGGTEEEEEEEETT-EEEEEEEE?SEE-----EEEEESS?EEEEEEESEEEEEETT?S-----S?EEEETT?EEEE?SSEEEEEEES---S?EEEEEE?? 3HQX|A PF06870.7_RNA_pol_I_A49_seed 24 501 !Q:0,2|4,6|13,29|36,37|46,47|55,60|68,68|72,72|79,80|85,95|102,102|104,107|110,500 Q:3,3|7,12|30,35|38,45|48,54|61,67|69,71|73,78|81,84|96,101|103,103|108,109 ???S???EEEEEE?----------??????EEEEEE-?SSEEEEEE??HHHHTTE------EEEEEEE?TTT?EEEEEE??EEEE-----------EEEETT?S????SS?????????????-???????????------??????????????--------??????????????????????????????-?????--????????????????????????????????-???????????????-???????-????????--------------------------------------------?????????-----??????????????????---------???????????????----???????????????????????????????--????????????????????-?????????????????????????????????????????????????????????????--?????????????? 3NFH|A PF06872.6_EspG_seed 4 414 !Q:10,62|70,71|76,76|98,100|106,108|112,114|130,130|132,132|135,136|139,140|144,144|147,149|152,152|155,156|167,167|171,174|177,182|200,201|205,205|215,215|228,228|232,233|236,245|258,258|260,261|277,277|289,289|294,295|318,328|337,350|358,361|363,364|368,368|384,384|387,388|399,399|403,403|412,413 Q:0,9|63,69|72,75|77,97|101,105|109,111|115,129|131,131|133,134|137,138|141,143|145,146|150,151|153,154|157,166|168,170|175,176|183,199|202,204|206,214|216,227|229,231|234,235|246,257|259,259|262,276|278,288|290,293|296,317|329,336|351,357|362,362|365,367|369,383|385,386|389,398|400,402|404,411 TTTHHHHHTT??????-----??????????????????????????????????????????SGGGEEE??STTS?TTEEEEEEETTEEEEEEEETT---EEEEE???SSS???EEEESSHHHHHHHHS?S?EE??SS??EEE?SS???SS?SS??HHHHHHHHHS?EEE????SB??--??TTTTTTHHHHHHHHHHT??TTT?EEEETTEEE?HHHHHHHHHHHT?SSS??TT?????---??HHHHHHHHHHHS?S??HHHHHHHHHHHHHTT?HHHHHHHHHTT?TTTT??BHHHHHHHHHHHHHHHHHHHHH???????????EEEEEEEE??????????????EEEEEEE----E??EEE?SSSEEEEEEEEEEEE?SS??SSHHHHHHHS?GGG?EEEEEEEE?? 4FMA|A PF06876.7_SCRL_seed 43 103 !Q:0,28|33,33|37,37|40,40|47,58|63,75|78,80|82,89|96,97|99,100|102,102 Q:29,32|34,36|38,39|41,46|59,62|76,77|81,81|90,95|98,98|101,101 ----------------?????------?-SSSS?EES-SS?HHHHHH------------HHHH???----------SS???B------??SSSEEB??S--S? 1UGL|A PF06877.6_RraB_seed 67 121 !Q:17,19|23,23|34,34|50,53|55,58|60,71|74,75|77,78|90,90|92,92|112,112|114,114 Q:0,16|20,22|24,33|35,49|54,54|59,59|72,73|76,76|79,89|91,91|93,111|113,113|115,120 HHHHHHHHHHHHHHHHT?-?TTS?EEEEEEEEES?HHHHHHHHHHHHHHT??-?B????B?----------?SS-?S--SBEEEEEEEEE?S?HHHHHHHHHHHHHHHHHHT?E-EEEEEE 1NXI|A PF06881.6_Elongin_A_seed 21 141 !Q:0,14|18,20|30,40|48,74|76,78|82,89|106,109|114,140 Q:15,17|21,29|41,47|75,75|79,81|90,105|110,113 -----??????????GGG?-?HHHHHHHHT??--???????HHHHHHH?????--------------------??S???SSS-------?HHHHHHHHHHHHHHHH----HHHH????????-----------------?? 4HFX|A PF06883.7_RNA_pol_Rpa2_4_seed 31 88 !Q:4,4|22,31|34,34|38,51|54,54|60,65|68,70|72,74|80,81|84,84 Q:0,3|5,21|32,33|35,37|52,53|55,59|66,67|71,71|75,79|82,83|85,87 EEEE?HHHHHHHHHHHHHHHHS----------TT?SSS?-------------TT?EEEEE???---SS--?S??-EEEEE??TT?EEE 4C3J|B PF06888.7_Put_Phosphatase_seed 9 250 !Q:0,0|5,5|14,14|25,25|42,42|49,49|55,55|57,59|70,71|73,73|84,84|88,88|90,90|112,112|119,124|130,130|138,138|141,146|149,150|152,152|154,160|173,176|178,179|188,188|194,195|201,201|203,212|219,223|230,230|235,237|240,240|246,246|249,249 Q:1,4|6,13|15,24|26,41|43,48|50,54|56,56|60,69|72,72|74,83|85,87|89,89|91,111|113,118|125,129|131,137|139,140|147,148|151,151|153,153|161,172|177,177|180,187|189,193|196,200|202,202|213,218|224,229|231,234|238,239|241,245|247,248 ?EEEE?IIIIIBSS?HHHHHHHHTT?HHHHHHHHHHHHTTSS?HHHHHH-HTTTT?B---HHHHHHHHHT??B?TTHHHHHHHH-HHT-T?EEEEEEEEEHHHHHHHHHHHT?SEEEEE------EEEEE-TTEEEEE?SS?-----ST--T-H-------HHHHHHHHHHHH----T??GGGEEEEE?SGGGH--HHHHH?S----------EEEEES?---?HHHHTT?SEEE--?SS?GGGGG-GG? 1F5S|A PF06890.7_Phage_Mu_Gp45_seed 8 190 !Q:0,78|83,83|87,87|99,99|103,109|116,122|131,131|145,145|151,151|156,161|163,163|168,168|179,179|181,181|183,183|189,189 Q:79,82|84,86|88,98|100,102|110,115|123,130|132,144|146,150|152,155|162,162|164,167|169,178|180,180|182,182|184,188 -------------------------------------------------------------------????????????EEEE?TTS?EEEEETTTEEE-EEE-------EEEEEE-------EEEEEEEE?SEEEESSEEEESS?EEESS?EEES------S?EEES?EEETTEETTT?B?B?TTSSB? 3VTN|A PF06905.8_FAIM1_seed 7 214 !Q:0,0|2,20|42,42|46,47|61,63|65,67|91,92|109,213 Q:1,1|21,41|43,45|48,60|64,64|68,90|93,108 ?T-------------------TEEEEEEEEETTEEEEEEEEE?TTT??EEEEETTEEEEEE???S???EEEEEEETTTTEEEEEEEEEETT--TEEEEEEEETTEEEEE??------------------------------------------------------------------------------------------------------- 2KD2|A PF06907.7_Latexin_seed 4 229 !Q:1,2|24,24|29,29|60,65|68,71|82,83|86,90|99,105|119,119|122,123|130,130|134,136|158,159|162,163|176,177|181,181|221,228 Q:0,0|3,23|25,28|30,59|66,67|72,81|84,85|91,98|106,118|120,121|124,129|131,133|137,157|160,161|164,175|178,180|182,220 E??TTSHHHHHHHHHHHHHHHHHH?BTTB?EEEEEEEEEEEEEETTTEEEEEEEEEEEET------TT??-?EEEEEEEEEE??TT?????EEEEEESS??????-HHHHHHHHHHHHH?SS??EEEEES?TTS???GGGHHHHHHHHHHHHHHHHHH??TT??EEEEEEEEEEEE??SSS?EEEEEEEEEEETTTTEEEEEEEEEEEETTTEEEEEEEEE???????? 1WNH|A PF06908.6_DUF1273_seed 41 200 !Q:0,4|11,12|18,20|23,24|44,45|47,47|49,51|56,58|76,77|80,80|90,90|96,96|110,110|119,119|122,133|155,156|160,161|178,181|186,186|195,197|199,199 Q:5,10|13,17|21,22|25,43|46,46|48,48|52,55|59,75|78,79|81,89|91,95|97,109|111,118|120,121|134,154|157,159|162,177|182,185|187,194|198,198 ?---?EEEEEE??HHHHT?-?SS??HHHHHHHHHHHHHHHHHHT--T-T-??EEEE???TTHHHHHHHHHHTTTTT-?TT?EEEEEESSB?TTTTS?HHHHHHHHHHHHH?SEEEESSS-SB??---------?HHHHHHHHHHHHHHSSEEEEE??TTT??TTHHHHHHHHHHHHHH-???EEEE?HHHHHHHH---H? 2NX2|A PF06917.7_Pectate_lyase_2_seed 5 576 !Q:0,13|31,32|38,39|41,41|43,43|47,47|51,52|54,54|58,58|62,62|68,68|72,72|87,88|108,108|111,111|113,113|116,116|120,120|127,128|131,133|136,137|140,141|144,147|155,155|180,180|182,182|184,184|187,201|207,212|220,222|235,237|244,245|264,264|268,271|273,273|278,280|282,286|289,291|295,296|307,307|310,311|317,317|370,371|377,377|379,379|384,384|387,387|392,392|395,395|398,399|401,401|403,404|419,420|436,436|439,439|447,447|450,450|453,457|472,473|498,498|505,505|510,510|526,526|531,540|546,546|550,550|563,563|567,575 Q:14,30|33,37|40,40|42,42|44,46|48,50|53,53|55,57|59,61|63,67|69,71|73,86|89,107|109,110|112,112|114,115|117,119|121,126|129,130|134,135|138,139|142,143|148,154|156,179|181,181|183,183|185,186|202,206|213,219|223,234|238,243|246,263|265,267|272,272|274,277|281,281|287,288|292,294|297,306|308,309|312,316|318,369|372,376|378,378|380,383|385,386|388,391|393,394|396,397|400,400|402,402|405,418|421,435|437,438|440,446|448,449|451,452|458,471|474,497|499,504|506,509|511,525|527,530|541,545|547,549|551,562|564,566 -------------?HHHHHHHHHHHHHHHTB??SSTTS??S?B?SEE?TTT??B?EEE?TTS?EEEEE?GGG?HHHHHHHHHHHHHH??THHHHHHHHHHHHHHHHSB?TT-S?BS?STT?EEETTT??EE???SS??SB??SS????HHHHHHH?HHHHHHHHHHHHHHHEEETTTTEE?S?B?TT?-----------???SGGGS??????TTEEESS???HHHHHHHHHHHH---HHHHHH??HHHHHHHHHHHHHTTTTS?TTT????S?SEEE???S-????TT???GGG??HHHHHHHHHH?TT??GGGEE?TTHHHHHHTHHHHHHHHHHHHTGGGGHHHHHHHHHHHHHHHHHHEETTTTEE??EETTS?B?TTEE?SS?BTTB?TT?EE??E-E??HHHHHHHHHHHHHS??HHHHHHHHHHHHHTT?EE?TTBTTBS?EE?TT?????HHHHHHHHHHHHHH??HHHHHHHHHHHHHHHHHHEETTEE?SSTTBS?EETT?SHHHHHHHHHHHHTT?GGGS??????????EEEEE?TTS?EEEEEEHHHHHH?BTT??????--- 2V8J|A PF06920.8_Ded_cyto_seed 25 228 !Q:0,7|17,18|20,20|23,24|27,27|29,37|41,41|56,56|64,65|74,86|108,108|111,121|134,135|139,140|152,153|155,158|175,183|200,201|207,208|218,218 Q:8,16|19,19|21,22|25,26|28,28|38,40|42,55|57,63|66,73|87,107|109,110|122,133|136,138|141,151|154,154|159,174|184,199|202,206|209,217|219,227 ????????EEEEEEEEE--E?TT--SS-S?--?----?GGG?EEEEEEEEEEEEES?SSSEEEE--EEEEEEEE------------?HHHHHHHHHHHHHHHHHHHHH?SS---------??HHHHHHHHHHHH??SSS??HHHHHHHHTSS??S----SHHHHHHHHHHHHHHH---------HHHHHHHHHHHHHHHH??GGGHH--HHHHHHHHH-HHHHHHHHH 2WMO|A PF06924.6_DUF1281_seed 4 136 !Q:4,5|19,19|21,22|44,47|50,53|56,56|63,66|68,68|85,85|87,87|107,108|113,113|134,134 Q:0,3|6,18|20,20|23,43|48,49|54,55|57,62|67,67|69,84|86,86|88,106|109,112|114,133|135,135 EEEE??HHHHHHHHHHHHT?S??HHHHHHHHHHHHHHHHHHTSS??--SS????TT?GGGGTT????S?HHHHHHHHHHHHHHTT?B?SSHHHHHHHHHHHTTTGGG??TTSS?SHHHHHHHHHHHHTHHHHTT?S 2IJR|A PF06931.6_Adeno_E4_ORF3_seed 7 114 !Q:18,19|40,40|42,42|50,50|54,54|64,65|96,100|103,104|109,110|113,113 Q:0,17|20,39|41,41|43,49|51,53|55,63|66,95|101,102|105,108|111,112 EEEEEEEHHHHHHHHHTT??HHHHHHHHHHHHHHTGGGGS?S?EEEEEEE?SSS-EEEEEEEEE??SHHHHHHHHHHHHHHHHHHHHHHHHHHHTS?????TT??EEEE??TT? 4DJB|A PF06936.6_Selenoprotein_S_seed 5 198 !Q:0,57|61,61|128,197 Q:58,60|62,127 ??--?????????-------???---???---?------------------------?HHH-HHHHHHHHHHHHHTTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?--------------------------------------------------------------------- 2Q2F|A PF06938.6_DUF1285_seed 81 195 !Q:3,3|7,7|15,17|34,37|43,43|46,46|55,55|66,66|68,69|73,74|84,84|88,88|90,90|94,94|97,129|131,131|135,137|140,142|150,155|161,161|172,172|177,181|195,195 Q:0,2|4,6|8,14|18,33|38,42|44,45|47,54|56,65|67,67|70,72|75,83|85,87|89,89|91,93|95,96|130,130|132,134|138,139|143,149|156,160|162,171|173,176|182,194 EEE?TTS?EEETTEE???HHHHHHHHTTEEEETT----EEEEE?SS?EEEEEESS?SEEEEEEEEE-S-?GGG?-EEEEEETTS?EEE?S-SSS?EE??-------------------------------B?TTT--?SB-??EEEEETT------EEEEE?HHHHHHHHTT?EEET-----TEEEEEETTEEEE- 2RE3|A PF06941.7_NT5C_seed 6 199 !Q:0,1|14,14|27,27|31,34|38,39|42,42|51,51|62,62|72,73|75,75|98,100|106,107|121,121|131,131|133,133|138,139|145,146|148,151|153,153|156,156|164,165|171,174|178,178|181,181|186,186|191,192 Q:2,13|15,26|28,30|35,37|40,41|43,50|52,61|63,71|74,74|76,97|101,105|108,120|122,130|132,132|134,137|140,144|147,147|152,152|154,155|157,163|166,170|175,177|179,180|182,185|187,190|193,198 ??EEEEEESBTTTB?HHHHHHHHHHHH?TTS????GGG??SS?HHHHHHHH?THHHHHHHHH-HTSTTTTTT??B?TTHHHHHHHHHTSTTEEEEEEE???SSGGG--THHHHHHHHHHHT?HHHHTTEEE?S?GGGS??SEEEE??S????S?SS?SSEEEEE??GGGTT????TTS?EE?STTS?HHHH--HHHHHT 1Z4P|X PF06953.6_ArsD_seed 38 160 !Q:0,4|10,24|38,38|43,44|53,53|71,71|75,76|90,92|97,101|107,159 Q:5,9|25,37|39,42|45,52|54,70|72,74|77,89|93,96|102,106 ???--EEEEE???????????????SHHHHHHHHHHHH-HHTT??EEEEETTT?TTHHHHSHHHHHHHHHH?GGG??EEEETTEEEEESS???HHHH-----HHHHT?????????----------------------------------??-------- 3MWH|A PF06954.6_Resistin_seed 11 100 !Q:0,5|23,24|29,33|52,53|56,56|67,69|81,82|85,89 Q:6,22|25,28|34,51|54,55|57,66|70,80|83,84|90,99 ??????HHHHHHHHHHHHHHHHH--HHHH-----TTEEEEEEEEEEESSEEE??TT?EEEEEEESTT???EEEETTTEEEE-?SS-??--SEEEEEEEEE 1RH7|A PF06955.7_XET_C_seed 134 76 !Q:0,15|20,20|23,23|26,26|32,33|35,38|60,60|64,64|66,66|68,71|73,73 Q:16,19|21,22|24,25|27,31|34,34|39,59|61,63|65,65|67,67|72,72|74,75 ?---------------TTTT?SG-GG-SGGGS--S??--HHHHHHHHHHHHHTEEEEGGG?TTT?S-S--??T-TH 2UWB|A PF06957.6_COPI_C_seed 5 436 !Q:0,121|130,132|141,141|154,154|156,158|173,173|177,177|183,187|191,192|199,200|204,207|209,213|232,232|250,253|285,287|306,308|343,345|363,364|368,369|371,372|376,378|384,385|387,388|392,393|396,396|400,401|404,404|412,412|422,429|434,435 Q:122,129|133,140|142,153|155,155|159,172|174,176|178,182|188,190|193,198|201,203|208,208|214,231|233,249|254,284|288,305|309,342|346,362|365,367|370,370|373,375|379,383|386,386|389,391|394,395|397,399|402,403|405,411|413,421|430,433 ------------------------------------------?---------------------------------------------------------------------??????????HHHHHHHH???HHHHHHTT?HHHHHHHHHHHS?B???GGGHHHHHHHHTTS?EEE?SSTTS-??--EEE??BTTTTT??SSS--??B?????HHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHGGG????SHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS???SHHHHHHHHHHHHHHTTS???HHHHHHHHHHHHHHHHHTTBHHHHHHHHHHHHHT???HHHHHHHHHHHHHHHHS??BSS??S??TTS???BBTTT??B??TTS??EE?TTT??EE?GGGTTSB?TTTSSBBSS????????SGGG?? 3MV3|A PF06958.7_Pyocin_S_seed 39 195 !Q:8,8|19,19|22,22|26,27|29,30|32,39|45,48|61,62|73,78|80,81|84,84|87,87|92,92|96,96|98,101|104,104|107,109|112,135|139,140|143,144|147,148|150,152|155,158|161,161|163,166|170,171|173,175|180,180|182,184|186,186|189,190|195,195 Q:0,7|9,18|20,21|23,25|28,28|31,31|40,44|49,60|63,72|79,79|82,83|85,86|88,91|93,95|97,97|102,103|105,106|110,111|136,138|141,142|145,146|149,149|153,154|159,160|162,162|167,169|172,172|176,179|181,181|185,185|187,188|191,194 HHHHHHTT?EEEBSEEEEE-EE?TTT??E--E--------EEEEE?--?TTTTTTEEEEEE?-EEEGGGTEEE------E??TT?SS?SEEE?TTS?S----EE?SS???EE------------------------EEE??TT??TB??S???TT??--EE?S????GGG??E---EEEE?T---T?SS??EEEE- 3MFB|A PF06962.7_rRNA_methylase_seed 17 148 !Q:7,7|23,25|27,31|38,38|46,47|49,53|61,61|63,64|66,74|100,105|121,121|135,135|138,140 Q:0,6|8,22|26,26|32,37|39,45|48,48|54,60|62,62|65,65|75,99|106,120|122,134|136,137|141,147 EEEEEES?HHHHHHHHHHHHHTT-??S-----EEEEES?GGGGGGT??S----?EEEEEEE?S??S?????????HHHHHHHHHHHHHHEEEEEEEEEEE??????HHHHHHHHHHHHHTS?TTTEEEEEEEESS?SS???EEEEEEE 3EEY|A PF06964.7_Alpha-L-AF_C_seed 145 501 !Q:5,6|13,26|29,30|36,39|42,45|74,74|80,111|116,116|119,119|121,122|126,126|139,141|146,147|151,152|154,325|327,328|331,331|338,339|346,348|355,358|366,368|371,373|380,380|382,412|415,415|417,422|431,435|437,438|441,441|443,444|446,450|452,457|460,471|473,474|476,476|478,481|486,486|491,491|494,499 Q:0,4|7,12|27,28|31,35|40,41|46,73|75,79|112,115|117,118|120,120|123,125|127,138|142,145|148,150|153,153|326,326|329,330|332,337|340,345|349,354|359,365|369,370|374,379|381,381|413,414|416,416|423,430|436,436|439,440|442,442|445,445|451,451|458,459|472,472|475,475|477,477|482,485|487,490|492,493|500,500 EEEEE??TTHHHH--------------TT??TTBSS?--?TT????BHHHHHHHHHHHHHHHHTTTTEEEEEEE?SBSSS?-------------------------------SEEE?TT-S-?EEE?TTHHHHHHHHHH??-SEEE??EEE??E----------------------------------------------------------------------------------------------------------------------------------------------------------------------------E??SS?SSEESE--EEEEEE---ETTTTE----EEEEEEE?-?SS-??EEEEEE?T-------------------------------TS?S-----?EEEEEEEE---??S?-TT?B??S-----S??????BS?--------???E--E-E----TTEE-EEEE?SS------E 4ATW|A PF06965.7_Na_H_antiport_1_seed 17 419 !Q:0,6|27,27|40,40|112,113|127,129|141,141|145,145|172,176|198,200|234,236|241,280|282,282|308,312|316,318|321,321|351,351|355,358|360,361|374,375|390,390|393,393 Q:7,26|28,39|41,111|114,126|130,140|142,144|146,171|177,197|201,233|237,240|281,281|283,307|313,315|319,320|322,350|352,354|359,359|362,373|376,389|391,392|394,418 ???????SSHHHHHHHHHHHHHHHHHH?SSSHHHHHHHTT?EEEEEETTEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHSTTTSSTTTSHHHHHHHHHHTTTTHHHHGGG??SSTTHHHHTSSSS???HHHHHHHHHSS?SSS?SSSHHHHHHHHHHHHHHHHHHHHHHS?????HHHHHHHHHHHHHHHHHHHTT???THHHHHHHHHHHHHTTTSHHHHHHHHHHHHHHS???GGGS----------------------------------------S?HHHHHHHHHHHHHHHTHHHHHHHHH?????SSS???TH-HHHSSTTTTHHHHHTTGGGSTTHHHHTSS?TTT????S??GGGGTTHHHHTT??HHHHHHHHHHHSTT-SS?SSHHHHHHHHHHHHHTTTSTTTGGG 1ZCD|A PF06968.8_BATS_seed 127 154 !Q:4,10|13,18|21,21|23,31|34,42|57,57|60,60|73,73|76,76|80,82|89,90|94,94|98,123|129,131|144,152 Q:0,3|11,12|19,20|22,22|32,33|43,56|58,59|61,72|74,75|77,79|83,88|91,93|95,97|124,128|132,143|153,153 EEEE--????-TT------ST-T---------SS----?????HHHHHHHHHHHHHH?TT-SEEEEESSGGGS?HH-HHH---HHHHHT??EEE?SSB--------------------------SSSSB???HHHHHHHHHHTT-?------?S 4JY9|A PF06969.11_HemN_C_seed 87 82 !Q:0,1|17,18|33,34|37,37|44,45|56,57|61,64|67,67|69,70|76,76 Q:2,16|19,32|35,36|38,43|46,55|58,60|65,66|68,68|71,75|77,81 ??HHHHHHHHHHHHHHH--HSEEEHHHHHHHTT??HH-HHTHHH--HHHHHHHHHT--TSE----EE?S--SEEEE?TTTGG 1OLT|A PF06971.8_Put_DNA-bind_N_seed 17 50 !Q:0,5|25,26|29,29|38,40 Q:6,24|27,28|30,37|41,49 ??????HHHHHHHHHHHHHHHHHTT??EE?HHHHHHHH???HHHHHHHHH 3IKT|A PF06973.7_DUF1297_seed 40 218 !Q:14,15|22,22|27,29|46,53|55,57|77,77|83,83|86,94|103,106|131,133|143,146|149,151|153,153|164,164|173,175|185,187|194,200|211,211|217,217 Q:0,13|16,21|23,26|30,45|54,54|58,76|78,82|84,85|95,102|107,130|134,142|147,148|152,152|154,163|165,172|176,184|188,193|201,210|212,216 HHHHHHHHHHTTTS??TTTGGG?EEEE???SEEEEEEEEEETTTTE--------E---EEEEEEEEEEEEHHHHTTS?HHHHH-TS----?????EEEEEEEE????GGGHHHHHHHHHHHHHHHHHHSTT???EEEEEEEEE---?TT---S?EEEEEEESSB?GGGGGGTT-??TTTTTTTSS???HHHHHH-------HHHHHHHHHT?GGGTB? 2R7M|A PF06977.6_SdiA-regulated_seed 24 270 !Q:0,5|8,8|14,14|18,18|21,22|24,25|45,45|56,57|64,64|67,68|77,77|98,101|104,105|109,111|117,119|121,121|123,125|128,129|160,165|168,169|174,174|179,181|184,185|188,193|218,219|222,223|230,230|237,237|240,242|250,250|253,254|261,261 Q:6,7|9,13|15,17|19,20|23,23|26,44|46,55|58,63|65,66|69,76|78,97|102,103|106,108|112,116|120,120|122,122|126,127|130,159|166,167|170,173|175,178|182,183|186,187|194,217|220,221|224,229|231,236|238,239|243,249|251,252|255,260|262,269 ??????TT?EEEEE-EEE?TT??S?-EEEEEEETTTTEEEEEEET-TEEEEEEETT??EEEEEE?SS-?SSEEEEEE?STTEEEEEETTTTEEEEEEE---?TT??EEE---EEEEE???S-S???SS??EEEEEETTTTEEEEEEESSSEEEEEEESTT-----?SS??EEEE?HHHH---HT??SS?---??EEEEETTTTEEEEEETTTTEEEEE?-TT??EEEEEE?STTGGG?SS???SEEEEEE?TT??EEEEET-TTEEEEEE 3QQZ|A PF06983.8_3-dmu-9_3-mt_seed 25 136 !Q:0,3|9,11|13,13|15,15|30,31|38,39|42,43|46,50|71,71|74,75|77,80|84,84|106,106|126,126|130,130 Q:4,8|12,12|14,14|16,29|32,37|40,41|44,45|51,70|72,73|76,76|81,83|85,105|107,125|127,129|131,135 ????EEEEE---S-S?HHHHHHHHHTTSTT??EEEEEE??TT?-SS----?TTSEEEEEEEETTEEEEEEE?SS??S????TTS?EEEEESSHHHHHHHHHHHHTT?EEEEEEEEETTEEEEEEEE?TTS?EEEEE 1U69|A PF06988.6_NifT_seed 36 70 !Q:0,2|8,8|11,13|32,33|38,38|48,50|54,57|61,61|64,64|68,69 Q:3,7|9,10|14,31|34,37|39,47|51,53|58,60|62,63|65,67 ?-?EEEEE?SS--?EEEEETTTTEEEEEEEES--SSSS?SSEEEETTS?--EEE????SSS?SS?EEE?? 2JN4|A PF06998.6_DUF1307_seed 14 144 !Q:5,6|10,10|15,15|24,24|27,27|46,46|52,56|58,62|79,79|86,86|101,102|107,107|112,113|116,119|126,127|141,142 Q:0,4|7,9|11,14|16,23|25,26|28,45|47,51|57,57|63,78|80,85|87,100|103,106|108,111|114,115|120,125|128,140|143,143 EEEEE--EEE-ETTE-EEEEEEEE-ET-TEEEEEEEEEEEETTTSS?SSHHH-----H-----HHHHHHHHTTTTTSSS?EEEEEE?SSEEEEEEEEETTS??HHHH-TTTT??TT?---HHHHHH??BHHHHHHHHHHTT??E 2JOE|A PF07005.6_DUF1537_seed 131 343 !Q:4,9|14,14|19,21|24,26|29,30|44,45|51,51|68,68|70,79|87,88|96,100|106,112|117,155|158,160|166,168|180,182|187,187|189,192|195,196|202,203|209,214|219,223|233,235|238,243|247,247|260,260|262,268|271,282|295,295|297,307|310,310|312,315|332,332|335,336 Q:0,3|10,13|15,18|22,23|27,28|31,43|46,50|52,67|69,69|80,86|89,95|101,105|113,116|156,157|161,165|169,179|183,186|188,188|193,194|197,201|204,208|215,218|224,232|236,237|244,246|248,259|261,261|269,270|283,294|296,296|308,309|311,311|316,331|333,334|337,342 TSSS?-----EEEE?HHHH---HH?--HH--HHHHHHHHHHHTT?-SEEEE?BSSHHHHHHHHHHHTT?S----------EEEESHH--HHHHHHH-----HHHTT?????-?GGGS??-------------------------------------SS?--EEEEE???SHHHHHHHHHH---TTTS?E----EE??GGGSS--SHHHH------HHHH-----HHHHHHHHH???SS---??-EEE?TTGGGHHHHHST-T???????HH------------HHHHHHHHHHHH-H-----------HT-T--??EEEEESHHHHHHHHHH-TT??EEEEEE 3DQQ|A PF07007.7_DUF1311_seed 182 147 !Q:0,7|10,11|13,13|19,19|22,23|27,28|41,43|52,60|64,64|66,66|69,74|81,83|85,88|97,97|110,110|112,117|126,128|134,135|147,147 Q:8,9|12,12|14,18|20,21|24,26|29,40|44,51|61,63|65,65|67,68|75,80|84,84|89,96|98,109|111,111|118,125|129,133|136,146 ??----??TT--T?HHHHH-HH--HHH--HHHHHHHHHHHH---HHHHHHHH---------HHH?S?TT------HHHHHH---H----HHHHHHHH-HHHHHHHHTTTS?T------TSHHHHHH---HHHHH--HHHHHHHHHHH- 3GI7|A PF07009.6_DUF1312_seed 40 137 !Q:0,37|54,54|57,57|67,70|74,74|91,95|98,98|104,105|107,107|111,111|113,113|127,129|131,136 Q:38,53|55,56|58,66|71,73|75,90|96,97|99,103|106,106|108,110|112,112|114,126|130,130 ??-------------------------------?????EEEEEEETTEEEEEEE?TT?BSEEEEEEE---?STT?EEEEEEETTEEEEEEE?---?SS?HHHHH??B?STT?E-EEETTTTEEEEEE---E???-?? 1NPP|A PF07015.6_VirC1_seed 4 232 !Q:0,0|6,7|30,31|37,38|41,41|49,50|53,54|58,61|65,68|90,91|94,94|105,105|113,113|115,115|125,128|134,141|149,150|157,157|160,164|176,180|182,182|184,185|187,191|203,205|211,211|230,231 Q:1,5|8,29|32,36|39,40|42,48|51,52|55,57|62,64|69,89|92,93|95,104|106,112|114,114|116,124|129,133|142,148|151,156|158,159|165,175|181,181|183,183|186,186|192,202|206,210|212,229 ?EEEEE??SSTTSSHHHHHHHHHHHHHHTT??EEEEE??TT?HHHHHHT--TS??SSE----EEE?---SSHHHHHTHHHTTTSSEEEEE??SS?HHHHHHHHHH?SEEEEEE?S?GGGHHHHHH----HHHHH--------HHHHHHH??EEEEEE?SB?????HHHHHHHHHHT??---B?S??B??---HHHHHHHHHTS?--GGGSS?HHHHHHHHHHHHHHHHHH?- 4E03|A PF07017.6_PagP_seed 10 154 !Q:8,11|17,23|26,30|32,33|35,41|65,65|69,69|83,84|87,88|103,104|108,108|111,112|134,140|144,144|146,147|149,150 Q:0,7|12,16|24,25|31,31|34,34|42,64|66,68|70,82|85,86|89,102|105,107|109,110|113,133|141,143|145,145|148,148|151,153 HHHHHHHH????EEEEE???????SS?????S??S???????EEEEEEEEETTTEEEEEEEEEEE?SSS?EEEEEEEEEEEEE??SS?-SSEEEEEEEEEEEE??SSS-SS??EEEEEEEEEEEETTEEEEEEB???----SSS?S??B??EEE 1MM4|A PF07021.7_MetW_seed 6 195 !Q:10,11|14,14|21,21|35,36|44,44|56,56|63,64|67,69|71,71|74,74|83,83|89,89|101,120|127,144|155,157|172,189|191,194 Q:0,9|12,13|15,20|22,34|37,43|45,55|57,62|65,66|70,70|72,73|75,82|84,88|90,100|121,126|145,154|158,171|190,190 HHHHHHHHHS??TT?EEEEES?TTSHHHHHHHHHS??EEEEEES?HHHHHHHHHTT?TEEEEE??TS??-S?TT?EEEEEEES?TTTSS?HHHHHHHHHTT--------------------EEEEEE------------------EEEEEEEESS???HHHHHHHHHHHHHH------------------T???? 3SM3|A PF07022.8_Phage_CI_repr_seed 14 168 !Q:11,11|23,24|30,131|139,141|153,155|162,163|165,165|167,167 Q:0,10|12,22|25,29|132,138|142,152|156,161|164,164|166,166 HHHHHHHHHHT?SSHHHHHHHTT??HHHHH------------------------------------------------------------------------------------------------------HHHHSSS??-HHHHHHHHHHH???HHHHHH??S?S? 2FJR|A PF07024.8_ImpE_seed 36 154 !Q:6,6|22,22|26,26|41,44|58,61|74,74|76,76|79,106|114,115|121,122|127,127|134,134|148,149 Q:0,5|7,21|23,25|27,40|45,57|62,73|75,75|77,78|107,113|116,120|123,126|128,133|135,147|150,153 TTEEES?EEESSTTTTTEEEEE?TTS?EEEEEGGGEEEEEE????SSGGGTEEEEEEE----ETTTEEEEEEEE?B?TT??--------------------------SHHHHTT??EEEEE-?SSSS?EEEEEB?EEEETTEEEEGGG??EEEE 1ZBP|A PF07039.6_DUF1325_seed 20 187 !Q:0,0|3,3|11,18|21,31|47,48|60,69|80,81|83,86|89,90|94,94|99,100|103,103|109,109|112,116|128,146|148,151|155,156|163,163|171,173|177,177|184,186 Q:1,2|4,10|19,20|32,46|49,59|70,79|82,82|87,88|91,93|95,98|101,102|104,108|110,111|117,127|147,147|152,154|157,162|164,170|174,176|178,183 ?TT?EEEEEEE-------?TT??---------EEEEEEEEEEEETTT--TEEEEEESSTT---???---?EEEEGGGEEE??S----BB??TTT?GGGS??TT?EEEEE?TT-----SSEEEEEEEEE?-----------------?S----STT??EEEEEB?TTSTTSB???EEE?GGGEEE??? 3MEU|A PF07045.6_DUF1330_seed 136 72 !Q:5,5|20,20|22,22|27,29|31,32|39,43|68,68 Q:0,4|6,19|21,21|23,26|30,30|33,38|44,67|69,71 HHHHH-HHHHHHHHHHHHTT?E-EEEE---S??EEEEES-???-SEEEEEEESSHHHHHHHHHSHHHH-HHH 2FIU|A PF07055.7_Eno-Rase_FAD_bd_seed 65 66 !Q:0,2|6,6|10,10|29,30|35,35|40,40|54,54|56,56|60,60|64,65 Q:3,5|7,9|11,28|31,34|36,39|41,53|55,55|57,59|61,63 ???TTS?EES?TTTTSHHHHHHHHHHGGG??GGGH-HHHS?HHHHHHHHHHHTT?S?SSS?TTS?? 4GGP|A PF07057.6_TraI_seed 8 129 !Q:0,44|57,57|74,74|79,81|85,88|91,93|101,101|105,105|114,114|124,126|128,128 Q:45,56|58,73|75,78|82,84|89,90|94,100|102,104|106,113|115,123|127,127 --------------------------------------------?HHHHHHHHHHHS?BGGGSHHHHHHHHHHT?TTSB???EEE????SS???EEEEEEE?TTS?EEEEEEEE?EEETTTEEE???S? 3FLD|A PF07061.6_Swi5_seed 20 99 !Q:14,22|35,44|48,48|84,84|94,95|98,98 Q:0,13|23,34|45,47|49,83|85,93|96,97 HHHHHHHHHHHHHH---------HHHHHHHHHHHT?---------SSS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS?GGGGHHHHT??TT? 3VIQ|B PF07063.8_DUF1338_seed 94 668 !Q:14,14|16,16|24,24|30,33|42,42|54,59|66,66|73,82|85,85|101,101|107,114|116,116|118,118|123,124|133,149|155,157|160,162|170,170|174,174|176,177|190,194|197,199|201,201|209,220|227,239|242,242|258,275|277,281|284,284|287,287|298,298|310,312|319,347|349,349|360,364|367,374|376,469|473,475|477,477|479,479|497,508|512,516|532,532|534,534|536,536|550,559|566,589|595,596|606,606|608,608|614,614|623,623|625,630|633,634|649,649|651,652|654,667 Q:0,13|15,15|17,23|25,29|34,41|43,53|60,65|67,72|83,84|86,100|102,106|115,115|117,117|119,122|125,132|150,154|158,159|163,169|171,173|175,175|178,189|195,196|200,200|202,208|221,226|240,241|243,257|276,276|282,283|285,286|288,297|299,309|313,318|348,348|350,359|365,366|375,375|470,472|476,476|478,478|480,496|509,511|517,531|533,533|535,535|537,549|560,565|590,594|597,605|607,607|609,613|615,622|624,624|631,632|635,648|650,650|653,653 HHHHHHHHHHHHHH-H?THHHHHH-HHHHH----HHHHHHHT?HHHHHHHHHTT-----?TTGGGT?EEEEEE----------ES?HHHHHHHHHHHHTTT?EEEEE--------E?G-GGGT?-SEEEEEEE??---------------SHHHH---HH???EEEEEEE?GGG?S--SHHHHHHHHHHH-----HT???S?HHHHHHH------------HHHHHH-------------SS?BHHHHHHHHHHHHHH------------------H??--?SB?SS?HHHHHHHHHH?HHHHHHHSSSS???SEEEEB?----------------------------S?HHHHHHHTGG-----GT????----S?--------------------------------------------------------------------------------------------?BSS???S-S?BSEEEEEEEEEEEEEEE------------TTE-----EEEEEEEEEEEEEEE?B?B?HHHHHHHHHHHTT??????????HHHHHH------------------------HGGGS??SHHHHHHTT?B?EEEEE?HHHHHTGG-G----??TT??HHHHHHTTSEEEEE?B??S?????????????? 2RJB|A PF07066.6_DUF3882_seed 2 162 !Q:0,2|8,12|16,17|25,26|36,39|43,43|64,64|67,67|73,77|103,104|109,109|119,120|141,141|144,146 Q:3,7|13,15|18,24|27,35|40,42|44,63|65,66|68,72|78,102|105,108|110,118|121,140|142,143|147,161 ???EEEEE?????STT??EEEEEEE--TTEEEEEEE????TTS?HHHHHHHHHHHHHHHHHHTT?TT?EEEEE?????SSHHHHHHHHHHHHHHHHHHBTTBS-?EEEE?HHHHHHHTT??SSHHHHHHHHHHHHHHTTSS?TT???HHHHHHHHHHHHHHH 4KTW|A PF07068.6_Gp23_seed 4 502 !Q:0,28|31,53|61,77|79,80|86,87|102,102|109,110|112,112|117,122|128,161|164,165|172,173|176,176|180,184|186,188|196,196|200,200|204,207|224,249|251,252|260,260|280,280|282,282|314,316|323,325|327,328|331,331|333,333|337,342|344,344|346,346|363,373|378,378|386,394|403,403|410,411|426,427|429,429|432,432|438,439|446,446|458,458|469,469|482,482|485,486|492,494|498,498|501,501 Q:29,30|54,60|78,78|81,85|88,101|103,108|111,111|113,116|123,127|162,163|166,171|174,175|177,179|185,185|189,195|197,199|201,203|208,223|250,250|253,259|261,279|281,281|283,313|317,322|326,326|329,330|332,332|334,336|343,343|345,345|347,362|374,377|379,385|395,402|404,409|412,425|428,428|430,431|433,437|440,445|447,457|459,468|470,481|483,484|487,491|495,497|499,500 ---------------------------??HH-----------------------HHHHHHH-----------------H??STTSS??HHHHHHHHHHHHHS?GGGSEE??B?SSEE------EEEEE?????--????--??????????????-??????EE??TTTTTT??TT?EEE-----E---TTEEEEE?SSS?SSS????SHHHHHHHHHHTTEEE??????????-------?????????S??EEEEEEE?EEEEEEEEEETTHHHHHHH-T?TTSTTHHHHHHHHHHHHHHHHHHHHHHHHSB???STHHHH---H--TT?B?STT----??S?S?HHHHHHHHHHHHHSTT??--------?EEEE?SHHHHTT---------TTTTSEES?SSTTSS??TTSEEETTSSEEEE??S?TT?EEEEE??TTEEEE?SEEEEEBEEEE?SEESESSSSS?EEEEEEEEEEEE?GG??STTTT---TTS?SS? 1YUE|A PF07071.6_DUF1341_seed 13 225 !Q:5,5|10,10|26,26|56,56|61,62|66,66|81,82|86,87|100,102|106,106|115,116|124,126|133,133|136,137|153,154|159,161|176,176|183,183|186,186|189,189|192,193|209,209|211,211|213,214|216,217 Q:0,4|6,9|11,25|27,55|57,60|63,65|67,80|83,85|88,99|103,105|107,114|117,123|127,132|134,135|138,152|155,158|162,175|177,182|184,185|187,188|190,191|194,208|210,210|212,212|215,215|218,224 BTTTB?EEEE?SSHHHHHHHHHHTTT?EEEEEEGGGSSSHHHHHHHHHHHHHHTTT?EEEE?-STT?GGGHHHHHHHHHHH??SEE??BGGGHHHHHHHH---TSS?SEEEEEEB??SSTTEEE???STTGGG-SS??EEEHHHHHHHHHHTT??EEEE???TTTTTHHHHHHHHH-HHHHTT?EE-EE?SS??TTTHHHHHHHHHHHT?S?B??B??GGGEETT 3LM7|A PF07072.6_DUF1342_seed 63 215 !Q:15,16|19,20|41,41|63,63|67,67|88,90|99,99|111,116|120,120|130,130|163,165|179,179|181,181|183,187|197,197|199,199 Q:0,14|17,18|21,40|42,62|64,66|68,87|91,98|100,110|117,119|121,129|131,162|166,178|180,180|182,182|188,196|198,198|200,214 HHHHHHHHHHHHHTT??ST--THHHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHHHTTTT?TTS?HHHHHHHHHHHHHHHHHHHH??-STTHHHHH?HHHHHHHHHHH??????GGG?HHHHHHHTS?HHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHT???EEEEEBTTEEEEE?S-S?---?EEEEEEEGG-G?EEEEEEEETTEEEEE 2OEZ|A PF07073.7_ROF_seed 31 107 !Q:2,3|18,18|23,23|27,28|34,34|38,45|49,49|53,73|78,78|88,89|94,97|105,105 Q:0,1|4,17|19,22|24,26|29,33|35,37|46,48|50,52|74,77|79,87|90,93|98,104|106,106 SS??SSHHHHHHHHTTTT?EEEE?TTT??EEESS?EEE??------SSS?EEE---------------------EEET-TEEEEESTT??SEEE----ETTTEEE?S 1SG5|A PF07075.6_DUF1343_seed 109 660 !Q:5,5|8,8|10,26|28,39|41,42|44,68|76,76|79,82|90,90|93,93|97,111|113,113|117,118|123,123|125,143|147,149|151,173|175,176|182,183|185,191|198,201|220,256|261,261|267,270|273,273|276,277|280,283|287,299|304,304|307,307|309,309|312,315|328,328|330,364|367,371|377,378|381,382|384,392|394,395|399,399|402,406|411,412|430,441|445,445|455,458|465,469|471,475|486,490|501,502|504,509|513,514|519,519|527,527|530,535|539,541|555,555|557,569|573,573|579,586|591,595|598,598|613,621|624,624|627,627|631,634|653,653|655,659 Q:0,4|6,7|9,9|27,27|40,40|43,43|69,75|77,78|83,89|91,92|94,96|112,112|114,116|119,122|124,124|144,146|150,150|174,174|177,181|184,184|192,197|202,219|257,260|262,266|271,272|274,275|278,279|284,286|300,303|305,306|308,308|310,311|316,327|329,329|365,366|372,376|379,380|383,383|393,393|396,398|400,401|407,410|413,429|442,444|446,454|459,464|470,470|476,485|491,500|503,503|510,512|515,518|520,526|528,529|536,538|542,554|556,556|570,572|574,578|587,590|596,597|599,612|622,623|625,626|628,630|635,652|654,654 EEEEE?TT?B?----------------T------------T??B-------------------------HHHHHHH?TT?---EEEEEEE?TT?SSS?---?????-?????B?TTT??BEEE?S-------------------GGG---S-----------------------S??HHHHT--T------?SEEEEE????SBTTSTHHHHHHHHHHHH-------------------------------------HHTT?EEEEE????TT?SS??BS????GGG------------?BTTB?SS-S?SB????HHHHHHHHHHTT?S-----------------------------------SS---??EEEEE??BS??T---------T??HHH-HT?????SSTT??SHHHHHHHHHHHHHHTT?-----------SSB?STTSSSTTS----EEEETT--??-H-----HHHHHHHHTT?---?TTEEEEEEEE??S------SST--TTTS?EEEEEEE-ES-----?TTT???TTHHHHHHHHHHH-H?------------GGG?HHHHS?-------GGGH-----HH-HHHHHTSTHHHHHH---------HH-HS?GGG----THHHHHTTHHHHHHHHHT-T??--? 4JJA|A PF07080.6_DUF1348_seed 7 144 !Q:0,0|3,3|6,7|26,26|48,48|91,91|95,95|108,108|112,112|126,126|130,133|135,136|140,141 Q:1,2|4,5|8,25|27,47|49,90|92,94|96,107|109,111|113,125|127,129|134,134|137,139|142,143 ?SS?SS??HHHHHHHHHHHHHHHTTT?HHHHHTTEEEEEEEEETTEEE?SHHHHHHHHHHHHHHSEEEEEEEEEEEEETTEEEEEEEEEEE?TTS?EEEEEEEEEEEE?TTS?EEEEEEEEEEEEE?GGG????S-?SSS??TT 2IMJ|A PF07081.6_DUF1349_seed 37 218 !Q:4,5|13,13|20,21|24,26|34,37|41,41|49,50|53,53|55,55|64,67|71,71|83,88|98,98|112,112|122,125|127,127|147,147|153,155|162,182|184,185|193,193|196,196|198,200|211,217 Q:0,3|6,12|14,19|22,23|27,33|38,40|42,48|51,52|54,54|56,63|68,70|72,82|89,97|99,111|113,121|126,126|128,146|148,152|156,161|183,183|186,192|194,195|197,197|201,210 EEES??SEEEEET-TEEEEE??SS-??EEESTTT??--EEE?SEEEEEE??SS-E-EEEEEEEE-???STT?EEEEEEEEETT------EEEEEEEEE-ETTEEEEEEEEEE-SSEEEEEEE?--?S?TTSEEEEEEEETTEEEEEE-ESSSS???EEEEEE-??----------------??S??EEEEEEE?SS-S???EEEEEEEEEE??????? 3O12|A PF07084.7_Spot_14_seed 10 192 !Q:0,9|31,31|33,33|40,45|48,85|89,90|109,143|186,191 Q:10,30|32,32|34,39|46,47|86,88|91,108|144,185 ????-?????TTSHHHHHHHHHHHHHHHHHH?S?GGGGTT??----TT?????-------------------------------??SSS??HHHHHHHHHHHHHHHHTT?????????????????????---???????????TTHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT---??? 3ONT|A PF07085.7_DRTGG_seed 171 125 !Q:7,7|12,14|17,18|20,20|22,22|27,27|30,30|41,44|55,57|67,67|69,74|83,83|86,89|101,106|110,110|113,113 Q:0,6|8,11|15,16|19,19|21,21|23,26|28,29|31,40|45,54|58,66|68,68|75,82|84,85|90,100|107,109|111,112|114,124 HHHHHTT?EEEE??-SS??E-E?EEEE?SS?HHHHHHHHHT?---SSEEEEEETT?--HHHHHHHTT?T------TEEEEEEE-TT????HHHHHHHHHHT----??EEE?SS?HHHHHHHHHTT 3L2B|A PF07088.6_GvpD_seed 5 566 !Q:0,0|36,38|47,47|57,58|70,74|77,89|91,94|97,100|102,103|107,109|127,127|134,138|147,148|152,153|170,170|183,183|195,195|199,199|202,203|205,206|219,222|224,224|227,229|240,241|246,246|248,266|269,270|272,272|277,278|288,290|292,292|299,299|303,306|323,324|333,333|341,341|343,345|357,360|364,364|366,366|372,385|396,410|417,417|426,426|429,432|444,447|454,454|462,462|467,469|471,471|474,475|479,479|482,484|508,510|512,512|523,523|528,533|539,539|542,543|545,545|550,550|553,553|555,565 Q:1,35|39,46|48,56|59,69|75,76|90,90|95,96|101,101|104,106|110,126|128,133|139,146|149,151|154,169|171,182|184,194|196,198|200,201|204,204|207,218|223,223|225,226|230,239|242,245|247,247|267,268|271,271|273,276|279,287|291,291|293,298|300,302|307,322|325,332|334,340|342,342|346,356|361,363|365,365|367,371|386,395|411,416|418,425|427,428|433,443|448,453|455,461|463,466|470,470|472,473|476,478|480,481|485,507|511,511|513,522|524,527|534,538|540,541|544,544|546,549|551,552|554,554 ?TTHHHHTTTSEEEEEESTTSSHHHHHHHHHHHHHH???EEEEESSS?HHHHHHHTT??HHHHHHTTSEE-----EE-------------E????SS?--?S??SSH---HHHHHHHHHHHHHHHHT?SEEEEE?----THHHHTTT??HHH--HHHHHHHHHHHHHHHT?EEEEEEESSSSS?HHHHSSEEEEE-EEE?ST--T??EEEEEEEEETTS????S?EE---EEEETTEEEE??TTTS?S???------------????EE??S?HHHH--HHTTSSEES---S?EEEEEE?TTS?---HHHHHHHHHHHHHHTT??EEEEESSS?HHHHHHH?H---HHHHHTTSEEE????GGG-S?HHHHH--------------HHHHHHHHTT-??------------SEEEEE?HHHHTSSS?HH----HHHHHHHHHHH----HHHHTT?EEEEEEE?SSSS???S?TT??GGG?SE---EEEEEEEEETTEEEEEEEEEEES???B?EEEETTEEEE?TTEE?-----STTSS?EE??T?STTS?TT?S??????????? 1U9I|A PF07090.6_DUF1355_seed 13 217 !Q:6,9|28,30|43,43|53,53|58,60|63,65|71,71|79,80|87,87|94,99|112,112|118,118|125,125|129,129|131,131|145,156|159,160|162,168|180,180|183,185|191,191|193,199|202,204|212,216 Q:0,5|10,27|31,42|44,52|54,57|61,62|66,70|72,78|81,86|88,93|100,111|113,117|119,124|126,128|130,130|132,144|157,158|161,161|169,179|181,182|186,190|192,192|200,201|205,211 EEEEEE-???EEEEEEEETTEEEEEEEE???SHHHHHHHTTTT?EEEEEETTH-HHHS???SH---HHHHT?SEEEEES??HHHHHS?HHHHTT??????HHHHHHHHHHTT?EEEEE?STTSSS?GGG?S?GGGSTHHHHSSEE----------??SS??E-------EEEEEEEEEEE?SS-??TTTTT?S-------EE---EEEEEEE---?? 3SOZ|A PF07091.6_FmrO_seed 14 283 !Q:0,0|8,8|26,26|47,47|50,52|63,67|73,73|83,94|96,99|114,115|128,131|139,139|145,146|151,152|155,156|180,181|187,190|195,198|200,201|209,209|230,230|239,248|266,268|278,278 Q:1,7|9,25|27,46|48,49|53,62|68,72|74,82|95,95|100,113|116,127|132,138|140,144|147,150|153,154|157,179|182,186|191,194|199,199|202,208|210,229|231,238|249,265|269,277|279,282 ?TTTTTTB?HHHHHHHHHHHHHHTTT?HHHHHHHHHHHHHHHTGGGS?SS???HHHHHHHHHH-----HHTTT?HHHHHHHHH------------H----HHTTSHHHHHHGGG--HHHHHHHHGGGS??-?SEEEETT?TTGGG??TTTT??TT?-EEEEEESBHHHHHHHHHHHHHTT??EEEEE?--?TTTS-???S??SEEEETT?HHHHHHHSTTHHHHHHHHSS?SEEEEEEE??????????HHHHHHHHHHHHHHHHT??-EEEEEETTE-EEEE 3FRI|A PF07100.6_ASRT_seed 25 124 !Q:0,1|9,11|13,26|28,28|35,35|39,39|52,53|62,62|73,74|76,77|80,83|86,86|103,123 Q:2,8|12,12|27,27|29,34|36,38|40,51|54,61|63,72|75,75|78,79|84,85|87,102 ??SEEEEEE???B??????????????S?EEEEEE?SSS?EEEEEEEEESSS??EEEEEEEE?TTEEEEEEGG--G??SS????SS?BEEEEEEEEEEEEEEE??????-?????????????? 1NC7|A PF07102.7_DUF1364_seed 13 100 !Q:0,5|11,12|14,16|20,23|27,27|32,48|56,56|68,68|70,72|74,74|98,99 Q:6,10|13,13|17,19|24,26|28,31|49,55|57,67|69,69|73,73|75,97 ??????TTTTS??S???TTT????GGG?EEEE---??????????????SSSEEEE?HHHHHHHTTSS?S---S?HHHHHHHHHHHHHHHHHHHHHTT?? 3G27|A PF07110.6_EthD_seed 57 122 !Q:0,1|3,3|25,57|71,72|83,85|87,88|105,108|114,114 Q:2,2|4,24|58,70|73,82|86,86|89,104|109,113|115,121 ??S?HHHHHHHHHHTHHHHHTTSTT-------------------------------??EEEEEEEEEBTTB??SEEEEEEEEE---S--SHHHHHHHHHSHHHHH----HHHHH-HHHTGGG 2FTR|A PF07118.6_DUF1374_seed 15 98 !Q:6,6|17,19|41,41|43,43|50,50|53,56|67,67|71,71|85,85 Q:0,5|7,16|20,40|42,42|44,49|51,52|57,66|68,70|72,84|86,97 HHHHHH-HHHHHHTSTT-??EEEEEEEEEEEEEHHHHHHTT?S?SEEEEE?ST----TEEEEEEEEE?SSS?EEEEEEEEEESSS-EEEEEEEEEEEE 2H36|X PF07124.6_Phytoreo_P8_seed 4 429 !Q:0,1|26,26|30,32|46,55|73,73|88,97|104,104|106,107|109,109|126,127|130,131|142,146|149,149|151,152|157,160|163,164|166,166|177,178|180,181|183,186|191,191|200,201|204,204|206,206|214,215|231,232|237,237|239,239|242,248|252,253|258,258|261,261|264,264|271,272|289,289|304,304|307,307|315,315|317,318|320,320|323,327|371,372|375,377|380,380|394,396|400,400|425,428 Q:2,25|27,29|33,45|56,72|74,87|98,103|105,105|108,108|110,125|128,129|132,141|147,148|150,150|153,156|161,162|165,165|167,176|179,179|182,182|187,190|192,199|202,203|205,205|207,213|216,230|233,236|238,238|240,241|249,251|254,257|259,260|262,263|265,270|273,288|290,303|305,306|308,314|316,316|319,319|321,322|328,370|373,374|378,379|381,393|397,399|401,424 ??HHHHHHHHHHHHHHHHHHHHHTTT?BSS???HHHHHHHHTTTTT??????????THHHHHHHHHHHHHHHH?TTTTTGGGSHHHHH???????-??HHHHHH?S??B?TTHHHHHHHHHHTSSS??SS??HHHHHHHHHH?????TT?B??HHHH????SS?-S?SSTHHHHHHS??S--S????EEEE?SSEEEEEE??SS?B?SEEEEEE??TTTTTEEEEEEEEEE??BSSS?B?SS?????-?TTS??EEEE?TT?SS?EEESSS??EEEEGGGSEEEEEESS?BSSEEEEEEEEEEE?TT?HHHHHTT?S??S-SS?????TTTHHHHHHHHHHHHTTTTHHHHHHHHHHHHHHHHHHTSSSSS??TT???SS?GGGTHHHHHHHTT?--TTS?HHHHHHHHHHHHHHHHHHHHHSTT???? 1UF2|C PF07130.7_YebG_seed 32 82 !Q:0,26|55,56|81,81 Q:27,54|57,80 ?????????????---------?????HHHHHHHHHHHHHHHHHHHHHHHHHSTT??HHHHHHHHHHHHTTHHHHHHHHHS? 3ERM|A PF07137.6_VDE_seed 7 199 !Q:0,25|30,30|32,34|39,39|50,51|57,58|80,80|84,84|97,97|100,100|107,109|113,113|125,125|131,131|159,160|176,177|184,185|189,198 Q:26,29|31,31|35,38|40,49|52,56|59,79|81,83|85,96|98,99|101,106|110,112|114,124|126,130|132,158|161,175|178,183|186,188 ----------------??????????GGGS?S???GGGG?EEEEEEEESS??TTTTS??EEEEEEETTTEEEEEEEEEEE?TTS?EEEEEEEEEEEE?SS?TTEEEE???GGG?EEEEEEEEEEE?SSSTT?EEEEEEEEEETTEEEEEEEEEEESSSS??GGGHHHHHHHHHHTT??GGGSEE??STT?????????? 3CQR|A PF07140.6_IFNGR1_seed 12 194 !Q:2,2|8,10|21,21|24,24|26,27|31,32|37,37|46,47|49,51|53,53|62,64|68,70|72,77|81,113|115,116|137,137|142,150|163,192 Q:0,1|3,7|11,20|22,23|25,25|28,30|33,36|38,45|48,48|52,52|54,61|65,67|71,71|78,80|114,114|117,136|138,141|151,162|193,193 SS?GGGTT???EEEEEEEETT?SS?E--EEE??GGGB?SSEEEEEE??S---S?EEEEEEEE??-SSS?-?B??????EEE------------------------?????????S??SGGGHHHHHHHHHHHHHHHS?HHHH---------HHHHHHHHHHHH------------------------------H 1FYH|B PF07143.6_CrtC_seed 69 470 !Q:11,11|14,17|29,52|54,56|67,75|81,81|92,93|95,95|97,98|102,104|107,107|113,119|128,128|130,146|149,149|156,156|161,169|176,177|179,181|184,184|192,192|194,194|198,202|204,204|211,212|225,225|228,230|234,242|245,251|263,269|271,271|273,273|285,289|294,295|297,297|299,302|314,314|316,338|347,347|350,350|352,352|354,354|356,356|359,363|372,372|378,378|382,383|394,398|403,408|415,415|417,418|422,422|427,428|432,437|451,458|466,466|468,469 Q:0,10|12,13|18,28|53,53|57,66|76,80|82,91|94,94|96,96|99,101|105,106|108,112|120,127|129,129|147,148|150,155|157,160|170,175|178,178|182,183|185,191|193,193|195,197|203,203|205,210|213,224|226,227|231,233|243,244|252,262|270,270|272,272|274,284|290,293|296,296|298,298|303,313|315,315|339,346|348,349|351,351|353,353|355,355|357,358|364,371|373,377|379,381|384,393|399,402|409,414|416,416|419,421|423,426|429,431|438,450|459,465|467,467 EEEEEEEEEEE?TT--??EEEEEEEEEEE???-------------????????S???EEEEEEEEEE--------?TTTSS?EEEEEEEEES--S?T--TTE---EE?SSEEE-------ETTEEEEE?T-----------------TS?EEEEEE?SSEE---------EEEEEE??S?-?EE?TBTTEEE?S-SST-----T?EEEEEE--EEEEEEEEEEEE-SS?--EEE---------EE-------EEEEEEEEEES-------S?S?TTEEEEEEEEE-----EETT--S?E----EEEEEEEETTS?E-----------------------EEEEEEEE?TT-S?E-E-EE----?GGGEEEEE-EEEEE?TTT??EEEEEEEEEE-----TTEE------EEEEES?S??EEE?TTBT??EEE------EEEEEEEETTEEE--------EEEEEEE-E?? 2ICH|A PF07145.10_PAM2_seed 53 18 !Q:0,3|6,6|9,13|17,17 Q:4,5|7,8|14,16 ????SS?TT?????TTS? 3KUS|C PF07152.7_YaeQ_seed 64 189 !Q:0,4|31,31|34,35|50,53|55,55|57,61|64,66|70,71|74,75|81,81|84,84|86,86|95,97|116,117|135,135|143,144|155,156|178,179|181,181|185,186 Q:5,30|32,33|36,49|54,54|56,56|62,63|67,69|72,73|76,80|82,83|85,85|87,94|98,115|118,134|136,142|145,154|157,177|180,180|182,184|187,188 ?????EEEEEEEEEEETTTTEEEEEEEEEEE?TT??HHHHHHHHHHHHHT??--S-S----?EE??-TTS-?SS??SEEEE?TT-S?EEEEEEES???HHHHHHHHHHSSEEEEEE??THHHHHHHHHHHHHHTT?SSEEEEE??HHHHHHHHTT??SEEEEEEEEETTEEEEEETTE--E-EEE??EE 2G3W|A PF07155.7_ECF-ribofla_trS_seed 62 196 !Q:0,3|23,23|25,29|31,31|33,34|37,37|39,41|56,57|77,78|80,80|101,102|104,104|106,106|110,116|122,123|143,159|161,161|175,175|189,190|196,196 Q:4,22|24,24|30,30|32,32|35,36|38,38|42,55|58,76|79,79|81,100|103,103|105,105|107,109|117,121|124,142|160,160|162,174|176,188|191,195 ??-?TTHHHHHHHHHHHHHHHHH-H--???B?S--SS?B-??TTHHHHHHHHHHSS??STHHHHHHHHHHHHHHHSS-?G-GGHHHHHHHHHHHHHHHHHH??S?S?SSH-------HHHHH--HHHHHHHHHHHHHHHHHHH-----------------S?HHHHHHHHHHHHH-HHHHHHHHHHHHH--HHHHH- 4HZU|S PF07160.7_DUF1395_seed 6 250 !Q:0,126|128,131|134,137|145,145|152,153|177,178|182,183|201,201|203,204|206,206|208,209|220,220|224,224|226,226|240,242|245,245|248,248 Q:127,127|132,133|138,144|146,151|154,176|179,181|184,200|202,202|205,205|207,207|210,219|221,223|225,225|227,239|243,244|246,247|249,249 ------------------------------------------------------------------------------------------------------------------------------?S--??SS????HHHHTTS?HHHHSS??HHHHHHHHHHHHHHHHHHHHHTT??TTT??HHHHHHHHHHHHHHHHT?S??S?S??EEHHHHGGGS?TTS?S?HHHHHHHHHTTTS???EE?SS?E 4AJ5|A PF07161.8_DUF1396_seed 17 241 !Q:0,0|5,6|17,18|29,35|38,40|53,53|56,57|68,69|74,74|92,92|102,103|107,108|113,114|116,116|127,127|149,152|157,157|165,165|168,169|171,172|174,174|176,176|187,204|207,208|215,215|217,217|221,221|223,226|236,240 Q:1,4|7,16|19,28|36,37|41,52|54,55|58,67|70,73|75,91|93,101|104,106|109,112|115,115|117,126|128,148|153,156|158,164|166,167|170,170|173,173|175,175|177,186|205,206|209,214|216,216|218,220|222,222|227,235 ?HHHH--HHHHHHHHHT??EEEEEEEEES?-----?TT?-?EEEEEEEEETTT-TE--EEEEEEEEET--TEEE-EEEEEEETTEEEEEEET-TEEEEEEEG--GGT??GGGG--G?TTTSHHHHHH-TEEEEEEEEEEEETTEEEEEE----EEEE?HHHHHHH?GG--G??S-S?EEEEEEEESS------------------TT??EEEEEE-E?STT?E----EEEEEESTT????? 3MHA|A PF07166.6_DUF1398_seed 6 125 !Q:15,17|28,28|45,45|49,49|55,55|59,63|65,67|82,84|97,98|113,113|116,117|124,124 Q:0,14|18,27|29,44|46,48|50,54|56,58|64,64|68,81|85,96|99,112|114,115|118,123 HHHHHHHHHHHHHHH???HHHHHHHHHH?SSEEEEETTTTEEEEE?SSS?EEEEE?STT?????S???HHHHHHHHHHHHHT???HHHHHHHHHHTT??EEEEETTTTEEEEE?TT??EEEEEE? 2HH8|A PF07171.7_MlrC_C_seed 15 192 !Q:7,7|12,17|26,26|28,28|31,38|45,46|57,57|60,60|68,68|71,71|75,77|94,95|102,102|116,117|119,120|129,133|143,144|148,148|155,155|171,171|174,176|182,182|187,188 Q:0,6|8,11|18,25|27,27|29,30|39,44|47,56|58,59|61,67|69,70|72,74|78,93|96,101|103,115|118,118|121,128|134,142|145,147|149,154|156,170|172,173|177,181|183,186|189,191 EEEEGGG?GGGT??????HHHHHHHH-H?TT??------EEEEEE-?HHHHHHHHHH?TT?EEEEEES?SS?TTS-??EEEEEEEEEEEEEEEE??SSTTTT?EEEEEEEEEEEET--T--EEEEEESS?????STHHHHHTT??GGG?SEEEES?SSTTHHHHTTTEEEE-EE???STTSS?GGGS??STT 3IUU|A PF07177.7_Neuralized_seed 6 71 !Q:1,3|7,7|10,10|16,17|20,21|25,26|28,28|31,32|39,41|44,45|53,54|60,61|69,69 Q:0,0|4,6|8,9|11,15|18,19|22,24|27,27|29,30|33,38|42,43|46,52|55,59|62,68|70,70 S??-EEE-EE?TTEEE??SS??EEE-?S?SS??EEEESS???SS??EEEEEEE??SSSSS??EEEEESS?G 2E63|A PF07180.6_DUF1401_seed 2 150 !Q:0,12|22,22|35,35|37,37|39,39|49,50|64,64|93,149 Q:13,21|23,34|36,36|38,38|40,48|51,63|65,92 ?????????????GGGGGGTTS?HHHHHHHHHHTT?S?B?HHHHHHHHT??HHHHHHHHHHHTT?TTTEEEEEEEEEETTTTEEEEEEEEEEE???????????????----????????????????-?????--------???????? 4KT5|C PF07181.6_VirC2_seed 5 206 !Q:0,81|88,91|95,95|106,106|135,142|146,150|157,158|174,174|176,176|200,203|205,205 Q:82,87|92,94|96,105|107,134|143,145|151,156|159,173|175,175|177,199|204,204 ---------------------------------------------------------------------------------?EEEEEE????TTS?HHHHHHTTTS?HHHHHHHHHHHHHHHHHHHHHTSGGGGS????????STT?????EEEEEE??HHHHHHHHHHHSTTS?S?HHHHHHHHHHHHHHHHHHHHHHT----T? 2RH3|A PF07190.6_DUF1406_seed 4 213 !Q:0,43|53,61|65,67|75,75|87,88|90,90|94,94|111,111|115,117|121,122|133,135|138,140|142,144|146,149|152,152|162,163|174,174|185,185|191,209|212,212 Q:44,52|62,64|68,74|76,86|89,89|91,93|95,110|112,114|118,120|123,132|136,137|141,141|145,145|150,151|153,161|164,173|175,184|186,190|210,211 -------------??---???---------------------??EEEEEEEEE??-??-???EEE?--SSEEEEE?SSEEEEEEEET??S?EEE-EEEEEETTEEEEEEEE?SSS???TTS??EEEEEEEETT???EE---E???S????SS?EEEEEEESS??SEEEEEEEEE?TTSGGSEEEE-EESSS???---------------?TT? 3ON9|A PF07191.7_zinc-ribbons_6_seed 20 74 !Q:0,3|7,7|9,10|13,13|15,17|22,22|26,27|35,35|39,39|41,43|54,55|57,57|61,64|73,73 Q:4,6|8,8|11,12|14,14|18,21|23,25|28,34|36,38|40,40|44,53|56,56|58,60|65,72 ????SSS?S??EE?S---SEEE?TTT??EEEEEEE?SSS?S???EEEETTEEEE??T-TTT????TTSSEEEE? 2JRP|A PF07194.6_P2_seed 80 99 !Q:8,9|12,12|31,31|39,39|44,44|48,52|54,55|68,68|78,78|83,89|97,98 Q:0,7|10,11|13,30|32,38|40,43|45,47|53,53|56,67|69,77|79,82|90,96 EEEEEEEE??TT?SSHHHHHHHHHHHHHHTT?EEEEEES?HHHH-HTT?----S--SSEEEEEEEESS?HHHHHHHHH-TSSS?------SEEEEEE?- 1U0S|A PF07196.8_Flagellin_IN_seed 132 91 !Q:1,1|8,10|12,22|27,28|34,34|41,49|62,68|73,78|84,86 Q:0,0|2,7|11,11|23,26|29,33|35,40|50,61|69,72|79,83|87,90 S?EETTEE???B--------???SSHH--HHHHH-HHHHHH---------HSHHHHTEEEEE-------ETTT------TEEEE---EESS 2ZBI|A PF07200.8_Mod_r_seed 17 157 !Q:3,3|15,15|28,31|53,56|68,68|123,123|125,128|151,153 Q:0,2|4,14|16,27|32,52|57,67|69,122|124,124|129,150|154,156 GGS?TTHHHHHHHHH?HHHHHHHGGGGS?--?HHHHHHHHHHHHHHHHHHHHH----HHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHTSSHHHHHHHHHHHHHHHHHHHHHHHHS?S????HHHHHHHHHHHHHHHHHHHHHH---HHH 2P22|C PF07201.6_HrpJ_seed 36 209 !Q:0,22|27,27|29,37|59,62|66,68|80,83|86,87|99,99|101,101|110,114|124,124|144,145|158,160|170,170|174,175|188,190|192,196|208,208 Q:23,26|28,28|38,58|63,65|69,79|84,85|88,98|100,100|102,109|115,123|125,143|146,157|161,169|171,173|176,187|191,191|197,207 ?--------------????????GGGS?E---------EEHHHHHHHHHHHHHHHHTTS????HHH---HHHHHHHHHSS?---SS??HHHHHHHHHHH?S?HHHHHHHH-----HHHHHHHHS?GGGHHHHHHHHHHHHHHHH--HHHHHHHHHHHH---HHHHHHHHT-TSS??HHHHHHHHHHHH---H??-??HHHHHHHHHHH? 1XKP|A PF07202.8_Tcp10_C_seed 8 183 !Q:1,1|5,5|9,9|14,14|18,18|23,23|33,33|37,37|66,66|71,71|75,75|80,80|84,84|89,89|93,93|98,98|102,102|110,110|114,114|123,123|128,128|132,132|137,182 Q:0,0|2,4|6,8|10,13|15,17|19,22|24,32|34,36|38,65|67,70|72,74|76,79|81,83|85,88|90,92|94,97|99,101|103,109|111,113|115,122|124,127|129,131|133,136 E-EEE?TTS?EEEE?TTS?EEEE?TTSSEEEEE?TTS?EEEEETTTTEEEEEETTTTEEEEEETTS?EEEE?TTS?EEEE?SSS?EEEE?TTS?EEEE?TTT?SEEEEEE?TTS?EEEEETTS?EEEE?TTS?EEEE?????????????????????????????????????????????? 4LZF|A PF07208.6_DUF1414_seed 27 45 !Q:2,3|24,25|45,45 Q:0,1|4,23|26,44 HT??HHHHHHHHHHHHHHHHHHHS-?TTSHHHHHHHHHHHHHHHS- 2JR2|A PF07212.6_Hyaluronidase_1_seed 2 279 !Q:1,3|8,9|20,23|25,26|31,32|44,44|49,52|54,61|63,65|70,70|74,77|80,81|83,83|85,91|93,94|97,97|99,105|108,109|111,111|114,118|122,122|125,131|134,135|138,138|141,146|150,150|152,158|162,162|165,170|181,182|184,193|196,202|204,208|211,213|215,215|230,230|234,234|238,238|240,243|246,253|258,260|276,278 Q:0,0|4,7|10,19|24,24|27,30|33,43|45,48|53,53|62,62|66,69|71,73|78,79|82,82|84,84|92,92|95,96|98,98|106,107|110,110|112,113|119,121|123,124|132,133|136,137|139,140|147,149|151,151|159,161|163,164|171,180|183,183|194,195|203,203|209,210|214,214|216,229|231,233|235,237|239,239|244,245|254,257|261,275 S???GGGS??HHHHHHHHHT----S??GGGS??HHHHHHHHTTS?BTTB????S????????S???SGGG?SSS????TT??S?S???????S??SS?S???????TT??S?SS?????SSS?SS???????SS??SS?SS??????TTS?S???????SSS?SS??????SSSSTTTTTT??S????????--TT???????S?????SS???S?SEEEEETTEEEEEE?TTS?EEE?S????SS????????STTS???HHHHHHHHHHHHHHH??? 2YX2|A PF07221.6_GlcNAc_2-epim_seed 20 470 !Q:2,7|9,9|11,11|15,15|22,23|44,47|50,50|53,53|55,55|57,59|73,75|80,83|85,85|89,90|92,92|96,96|98,98|101,102|110,112|121,121|123,125|130,130|132,134|137,138|143,145|147,150|157,162|174,174|176,177|180,180|183,184|186,187|189,196|199,202|207,208|216,216|224,227|230,231|234,241|258,262|268,269|273,273|277,277|279,279|289,289|293,293|297,297|309,312|315,318|320,320|322,328|331,333|353,353|357,358|361,361|364,364|366,366|370,370|374,379|382,383|395,397|404,404|406,409|412,414|432,432|434,434|436,436|438,438|441,441|445,445|449,449|451,452|454,455|457,457|460,460|463,463 Q:0,1|8,8|10,10|12,14|16,21|24,43|48,49|51,52|54,54|56,56|60,72|76,79|84,84|86,88|91,91|93,95|97,97|99,100|103,109|113,120|122,122|126,129|131,131|135,136|139,142|146,146|151,156|163,173|175,175|178,179|181,182|185,185|188,188|197,198|203,206|209,215|217,223|228,229|232,233|242,257|263,267|270,272|274,276|278,278|280,288|290,292|294,296|298,308|313,314|319,319|321,321|329,330|334,352|354,356|359,360|362,363|365,365|367,369|371,373|380,381|384,394|398,403|405,405|410,411|415,431|433,433|435,435|437,437|439,440|442,444|446,448|450,450|453,453|456,456|458,459|461,462|464,469 SB-??---E-E?TTS?EEESSE--EEHHHHHHHHHHHHHHHHHH-?-?HH-HH-H-H---HHHHHHHHHHTTB--?TTTS---?B?SEE--E-TTE-E-EE??EEHHHHH---HHHHHHHH-H---HHTT?T---TH--HHHH---H----HHHHHH------HHHTEETTTTE-E??EE?TT??B?-S?-------EE----HHHH--HHHHHHH-HHHHHHH?--?HH--HH--------HHHHHHHHHHHTHHHH-----TTTTS??SEE?TTS?B?TTTTTTSTT?SSS?SSB?HHHHHHHHHHH----HH----H-H-------HH???TTHHHHHHHHHHHHHHHHB?TTT?-SB?SE-E?TTS?EEE----??EE--HHHHHHHHHHH---HHHHHH-H??--HH---HHHHHHHHHHHHHHHTB?T-T-T?SB?SEE?TTS?B??S??B?TT?SS-HHHHHH 3GT5|A PF07228.7_SpoIIE_seed 173 337 !Q:0,0|11,11|14,18|23,24|40,40|44,75|88,88|94,118|121,121|128,135|141,141|151,154|158,158|160,160|163,171|175,179|181,185|189,189|191,214|219,220|223,223|229,229|234,243|245,245|248,249|258,261|270,286|299,317|323,324|327,327|336,336 Q:1,10|12,13|19,22|25,39|41,43|76,87|89,93|119,120|122,127|136,140|142,150|155,157|159,159|161,162|172,174|180,180|186,188|190,190|215,218|221,222|224,228|230,233|244,244|246,247|250,257|262,269|287,298|318,322|325,326|328,335 ?SSEEEEEEEE?SS----?SHHH--HHHHHHHHHHHHHHH-HTT??------------------------------HHHHHHHHHHHG-GGSTT?------------------------TT?EEEEEE--------EETTT?EEEEEEESS??-?EEE?T-TS--------?EEE??-??S???--TTS-S?-------------------????EEEE??TT?EEEEE?TTTT----------S?TT??HHHHHHHH----HHHHHHHT?????????----????HHHHHHHHHHHH-------------------HHHTT??SS?EEEEEEEE? 3PU9|A PF07229.7_VirE2_seed 4 560 !Q:0,113|136,136|139,141|154,154|158,158|161,161|170,172|178,183|208,216|218,218|221,224|229,230|238,238|242,242|246,246|248,249|260,261|267,267|270,270|276,278|281,281|286,287|300,300|303,303|309,309|313,313|338,347|353,366|378,378|381,381|391,392|400,400|408,408|416,416|429,430|436,448|451,451|457,457|463,463|468,468|472,478|487,487|491,491|507,510|517,559 Q:114,135|137,138|142,153|155,157|159,160|162,169|173,177|184,207|217,217|219,220|225,228|231,237|239,241|243,245|247,247|250,259|262,266|268,269|271,275|279,280|282,285|288,299|301,302|304,308|310,312|314,337|348,352|367,377|379,380|382,390|393,399|401,407|409,415|417,428|431,435|449,450|452,456|458,462|464,467|469,471|479,486|488,490|492,506|511,516 ??????????????????????????????????????????????????????????????????????????????????????????????????????????-???????TTSEEEEEEEETTEEEEEEGGG?SS???HHHHHHSEEEEE?TTS?EE?HHHHHHTS???HHHHH??????STHHHHHHHHHHHHHHHHHHHHHT?????????B?TT????TTSS??GGGSEEE?SSS?EEE?S??BSSTTTTTTT??SEEEE?TT?BEEEE???TT?TTTT??HHHHHHHHHHHH?TT?EEEEE?TTS?EEEHHHHHHHSTTHHHHHHHHHTT??????????SEEEE??????????????EEEEHHHHHHH?TT?HHHHHHHTT??GGGEEEE?TTSSEEE?HHHHHHH?HHHHHHHHHHHT??GGGGG?????????????SS?SEEEE?SSEEE?GGGS?TTT?-?????TTEEEEEE?TTS?EEEEEEEHHHHHHTT????HHHHHH??????????????????????????--??????????????? 3BTP|A PF07233.7_DUF1425_seed 37 95 !Q:20,20|22,22|25,25|35,35|39,39|50,50|54,54|56,58|61,63|69,69|72,72|80,80|85,86|95,95 Q:0,19|21,21|23,24|26,34|36,38|40,49|51,53|55,55|59,60|64,68|70,71|73,79|81,84|87,94 EEEEETTEEEEEEEEEEEEE?G-GG?EEEEEEEEE?SSS?EEEEEEEEEE?TTS?B???TT???EEEEE?TT?EEEEEEE?SSTT??EEEEEEEE- 3O0L|A PF07236.6_Phytoreo_S7_seed 4 530 !Q:0,295|302,529 Q:296,301 ??????????????????????????????????????????--??????????????????????????????????????????????????????????????????????????????????-??????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????--?????????????????EEEEES?????????--???????---????????????????????????????????????????????????????---???????????????????????????????????-??????????????---???????????????????????????????????????????????????????????????-------????????????????????????????? 1UF2|K PF07237.6_DUF1428_seed 72 136 !Q:0,0|30,30|34,34|44,59|61,73|76,77|84,85|99,99|112,115|117,117|123,123|127,127|129,129|131,131|133,133 Q:1,29|31,33|35,43|60,60|74,75|78,83|86,98|100,111|116,116|118,122|124,126|128,128|130,130|132,132|134,135 ?EEEEEEEEEEGGGHHHHHHHHHHHHHHHH-HTT?SEEEEEEEE----------------E????---------SS??HHHHTT??TTEEEEEEEEEES?HHHHHHHHHHHH----T?HHHHH-TTS-S?S-S?TT 2OKQ|A PF07238.9_PilZ_seed 191 218 !Q:2,2|5,15|23,40|50,58|60,64|71,71|76,77|81,86|90,93|96,106|109,116|121,121|129,150|153,153|155,160|172,181|184,184|190,192|195,200|214,214|217,217 Q:0,1|3,4|16,22|41,49|59,59|65,70|72,75|78,80|87,89|94,95|107,108|117,120|122,128|151,152|154,154|161,171|182,183|185,189|193,194|201,213|215,216 ES?SS?---------?EEEEEEE------------------EEEETTEEE---------E-----EEEEEE?SSEE--EEE?----?TTS????TT?----------EE--------EEEE-EEETTEE----------------------EE?S-----?EEEEEEEEEEE----------SS?EEEEE---EE-----?HHHHHHHHHHHHT?EE? 1YLN|A PF07239.6_OpcA_seed 2 244 !Q:0,6|19,21|25,27|58,63|65,66|71,71|74,74|76,81|84,84|126,126|170,170|179,179|184,185|217,221|234,237 Q:7,18|22,24|28,57|64,64|67,70|72,73|75,75|82,83|85,125|127,169|171,178|180,183|186,216|222,233|238,243 ???????EEEEEEEEEEEE???SSS???EEEEEEEEEEEEEESSSSEEEEEEEEEEEE??????B??STTS?SS?S??????SS?SEEEEEEEEEEEEEEEETTEEEEEEEEEEEEEEEEEEEBSS?EEEEEEEEEEEEEEEEEEEEEETTEEEEEEEEEEEEEEEEEEE?GGGTTTSS?EEEE??EEEEEEEEEEEEEETTTEEEEEEEEEEEEEE?????EEEEETTEEEEE????EEEEEE 1K24|A PF07244.10_Surf_Ag_VNR_seed 395 172 !Q:0,0|3,7|10,10|12,12|14,35|38,38|41,43|47,50|52,52|55,59|61,71|73,74|77,81|85,85|89,90|97,100|107,109|117,118|120,122|124,125|127,130|135,143|147,150|153,164|169,171 Q:1,2|8,9|11,11|13,13|36,37|39,40|44,46|51,51|53,54|60,60|72,72|75,76|82,84|86,88|91,96|101,106|110,116|119,119|123,123|126,126|131,134|144,146|151,152|165,168 ?EE?--??EE-E-S---------?----------?-SS?HH---HHH----H-HS-----S-----?----?S??SS?----SSS?TTB??HHHHHH----HHHHHH---HHHHTTT?-S---S??E----EEEE?--???---TTS---?EE----------??EEEE??? 2QDF|A PF07245.6_Phlebovirus_G2_seed 4 507 !Q:6,7|19,19|32,34|45,45|50,50|74,75|86,86|92,92|100,101|104,106|113,116|118,118|127,128|134,134|139,139|154,155|174,174|178,178|185,185|188,188|203,204|206,206|212,212|228,230|233,234|259,259|262,262|277,280|302,302|306,307|313,313|315,317|331,332|334,338|354,354|366,366|378,378|385,385|396,397|413,414|423,423|425,506 Q:0,5|8,18|20,31|35,44|46,49|51,73|76,85|87,91|93,99|102,103|107,112|117,117|119,126|129,133|135,138|140,153|156,173|175,177|179,184|186,187|189,202|205,205|207,211|213,227|231,232|235,258|260,261|263,276|281,301|303,305|308,312|314,314|318,330|333,333|339,353|355,365|367,377|379,384|386,395|398,412|415,422|424,424 EEEEEE??GGGEEEEESSS?EEEEEEEEEEEE???BTSEEEEEEE?SSTT?EEEEEEEEEEEEEEEEEEEEEEE??EEEEEEEEEE?TTSTT?STTTTTT??TT???GGGGGG????B?EEEEEEEE??SGGGT?SSSS?EEEEEEEEEEESSS??EEEEEEEEEEEEEEEEEE?TTS?EEEEEE?TT?EEEETTEEEEEEEE??S?TTGGG?EEEEETTTEEEEESS???SS??TTSTTSEEBSSHHHHHTTBTTSEE?TT?EEEEEETTEEEEEE????HHHHHHHTBSSEEETTEEEEE?SSS??EEEEE?S???EEEEEEEEEEEEE??S?????EEEEEEEEEBSSSSS?EEEEEEEEESS?EEEEEEETTSS?EEEEEE?BEEEEEEEEE??SSSEEEEEEEEESSS??EEEEEEEE?B????------------------------------------------------------------------------------ 4HJ1|A PF07249.7_Cerato-platanin_seed 5 124 !Q:0,1|5,5|8,9|13,13|20,21|26,26|31,33|41,41|51,52|56,56|59,59|61,61|81,81|88,88|98,99|104,105|107,107|109,109|114,115 Q:2,4|6,7|10,12|14,19|22,25|27,30|34,40|42,50|53,55|57,58|60,60|62,80|82,87|89,97|100,103|106,106|108,108|110,113|116,123 ??EEE?SS?-STT?BGGGSS??STTT?STTT?--SBSSSSS?SSSEEEETT??STT?TT?S?EEEEEETTTEEEEEEEEEE?SSSEEE?HHHHHHHHS--SSSS??B?S?EEEE??HHHHHHHH 2KQA|A PF07252.6_DUF1433_seed 17 102 !Q:16,16|19,24|28,30|38,38|47,47|55,55|59,67|73,73|76,76|81,84|86,93 Q:0,15|17,18|25,27|31,37|39,46|48,54|56,58|68,72|74,75|77,80|85,85|94,101 HHHHHHHHHHHHHHHH?TT---???EEE???EEETTEE-EEEEEETT?TTSEEEE?STT---------TSEEE?HH-HHTT??--S?-??---?HHHHHHTT 2K3D|A PF07261.6_DnaB_2_seed 110 86 !Q:8,9|13,15|30,34|47,47|50,51|53,57|73,74|80,85 Q:0,7|10,12|16,29|35,46|48,49|52,52|58,72|75,79 HHHHHHHH--HTS???HHHHHHHHHHHTTT--???HHHHHHHHHHHH-HH--T???--HHHHHHHHHHHHHTT??SHHHH??---- 2ZC2|A PF07262.6_DUF1436_seed 9 163 !Q:0,1|9,9|12,12|27,27|31,32|36,36|39,40|55,56|58,61|71,71|92,92|102,102|119,119|129,129|132,133|141,142|146,147|161,162 Q:2,8|10,11|13,26|28,30|33,35|37,38|41,54|57,57|62,70|72,91|93,101|103,118|120,128|130,131|134,140|143,145|148,160 ??EEEEEEE?SS?EEEEEEEESSSEEE?TTS??EEE?TT??HHHHHHHHHHHHHT??B?--?SHHHHHHHH?TTTTHHHHHHHHHHHHHHHT?SSHHHHHTT?EEEEEEEETTEEEEEE?EEEETTEEE?TT??GGGSEEE--ETT??HHHHHHHHHHHHT?? 2GKP|A PF07264.6_EI24_seed 191 407 !Q:0,0|8,10|17,29|47,50|59,60|68,139|154,156|161,163|176,182|191,193|198,222|225,228|231,235|249,251|266,267|272,273|276,278|284,285|288,290|293,296|305,325|337,345|350,350|352,353|359,359|379,392 Q:1,7|11,16|30,46|51,58|61,67|140,153|157,160|164,175|183,190|194,197|223,224|229,230|236,248|252,265|268,271|274,275|279,283|286,287|291,292|297,304|326,336|346,349|351,351|354,358|360,378|393,406 ?STTHHHH---HHHHHT-------------STTTHHHHHHHHHHHHH----HHHHHHHH--HHHHHHH?---------------------------------???????????----------------------?????TTHHHHHHHHHHHH---HHHH---HHHHHHHHHHHH-------HHHHHHHH---HHHH-------------------------TT?-??TT----?SSGGGSSSHHHHH---HHHHHHHHHHHHHH--HHHH--HH---HHHST--TH---HH----HHHHHHHH---------------------HHHHHHHHHHH---------HHHT-T??HHHHH-HHHHTTHHHHHHHHHHHHH--------------HTTSTTGGGTHHHH 3TX3|A PF07273.7_DUF1439_seed 38 161 !Q:9,12|17,20|48,48|51,51|66,66|115,115|132,132|136,137|141,141|151,154 Q:0,8|13,16|21,47|49,50|52,65|67,114|116,131|133,135|138,140|142,150|155,160 EEHHHHHHH----HHHH?-??EEEEEETTTEEEEEEEEEEEEEESSSS-TT?EEEEEEEEEEEEET-TEEEEEEEEEEEEEEEEEETTTTEEEEEEEEEEEEEEESTHHHHHHHH-HHHHHHHHHHHHHHHS?SEE??SSS?HHHHHHHHH????EEETTE 3L6I|A PF07275.6_ArdA_seed 38 261 !Q:19,20|25,26|32,34|39,46|49,90|99,100|102,105|107,109|112,113|124,124|126,136|140,141|153,156|161,161|176,178|181,181|186,191|202,207|211,214|217,218|220,222|226,227|229,229|237,240|249,250|260,260 Q:0,18|21,24|27,31|35,38|47,48|91,98|101,101|106,106|110,111|114,123|125,125|137,139|142,152|157,160|162,175|179,180|182,185|192,201|208,210|215,216|219,219|223,225|228,228|230,236|241,248|251,259 EEEEEEEEEESSSSEEEEE--EESS??HHHHH---HHHT??------TT?----------------------------------------?SEEEEEEE-?S----S???TT??HHHHHHHHHH-H-----------HHS?-HHHHTTHHHHT----TTSS?HHHHHHTGGGEEEE---TT?SSHH------HHHHHHHHTT?-----TTS???-TG--G---GGG--B?HHHHHHH----HHHHSEEE--EETTEEEEE? 2W82|A PF07286.7_DUF1445_seed 77 168 !Q:5,6|8,9|19,23|30,33|41,43|48,49|51,51|73,80|82,82|87,88|90,90|95,97|101,101|105,111|115,126|133,133|146,149|158,160|163,163|166,166 Q:0,4|7,7|10,18|24,29|34,40|44,47|50,50|52,72|81,81|83,86|89,89|91,94|98,100|102,104|112,114|127,132|134,145|150,157|161,162|164,165|167,167 EEEEE??S??SHHHHHHHT--???HHHHTT????EEEEEEE???BTTB??E-EEEEEEEEEGGGHHHHHHHHH?????-??S?SEES-?G-GGGT???TTS?SBS???-???TTE------------EEEEEE?TTHHHHHHHHHT---?SEEEEEBT---TB?EE?S 2PIF|A PF07299.6_FBP_seed 15 217 !Q:0,0|2,2|23,25|44,44|47,48|63,64|80,86|100,106|113,113|132,132|135,136|145,145|147,150|155,155|159,162|174,178|180,180|183,185|202,204|216,216 Q:1,1|3,22|26,43|45,46|49,62|65,79|87,99|107,112|114,131|133,134|137,144|146,146|151,154|156,158|163,173|179,179|181,182|186,201|205,215 ?B?HHHHHHHHHHHHHHHHHHHH???HHHHHHHHHHHHHHHHTT?SS??HHHHHHHHHHTSTT??HHHHHHHHHHHHTTB???????HHHHHHHTTTSTT???????HHHHHT?SEEEEEEGGGTEEEEEEE?TT??EEEEEEEE?S--??EEEE?TTT?---SEEEEEEEEEE??-??T-TS???EEEEEEESSHHHHHHH???HHHHHHHHHHT? 4ADN|A PF07303.8_Occludin_ELL_seed 18 111 !Q:1,5|37,37|47,47|51,51|53,55|65,68|74,74 Q:0,0|6,36|38,46|48,50|52,52|56,64|69,73|75,110 S??-??SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHH-HHS?T---TSHHHHHHH----HHHHH-HHHHHTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 1WPA|A PF07304.6_SRA1_seed 4 186 !Q:0,59|79,79|101,101|103,103|121,121|160,185 Q:60,78|80,100|102,102|104,120|122,159 ---------------------------?----????-----------?????----????HHHHHHHHHHHHHHHHTTS?HHHHHHHHHHHHHHHHHHHHT?S?HHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHSTHHHHTTTHHHHHHHHHHHHHHHS??-----------------------? 2YRU|A PF07311.7_Dodecin_seed 80 67 !Q:0,0|14,14|30,32|48,48|65,66 Q:1,13|15,29|33,47|49,64 ?EEEEEEEEEEESS?HHHHHHHHHHHHHHH???EEEEEEEEEEEEEET-TEEEEEEEEEEEEEEE?? 2CZ8|A PF07313.7_DUF1460_seed 25 268 !Q:8,8|11,11|14,16|18,18|21,21|25,25|27,27|30,30|33,33|35,35|49,49|52,57|74,76|82,83|102,102|106,106|108,108|112,112|114,115|119,120|131,132|136,136|138,138|141,142|160,163|167,168|179,180|185,186|194,194|197,197|207,208|215,215|231,234|246,247|264,264|267,267 Q:0,7|9,10|12,13|17,17|19,20|22,24|26,26|28,29|31,32|34,34|36,48|50,51|58,73|77,81|84,101|103,105|107,107|109,111|113,113|116,118|121,130|133,135|137,137|139,140|143,159|164,166|169,178|181,184|187,193|195,196|198,206|209,214|216,230|235,245|248,263|265,266 HHHHHTTT?BB?TT???S?TT?SSB?S?SS?SS?B?HHHHHHHHHHHHH?SS------HHHHHHHHHHHHBGGG??-STTTB??STTTTHHHHHHHTTSEEE?GGG?B?TTS?B??EEE??EEEHHHHHHT??GGG?B?SS??HHHHHHHHHHHHHHHTT?--?EEE??EEEEEHHHHT--GGGS??HHHHTTS?TT?EEEEEEEEE??HHHHSS?EEEEEEEEEEEETTE----EEEEEEETTTT--EEEEEEHHHHHHHHTT?SS? 4H4J|A PF07315.6_DUF1462_seed 18 99 !Q:4,4|7,8|15,16|32,32|36,38|48,48|50,55|60,60|72,72|88,89 Q:0,3|5,6|9,14|17,31|33,35|39,47|49,49|56,59|61,71|73,87|90,98 EEEE?SS??GGGSSS??HHHHHHHHHHHHHHH?TTS--?EEEEEEETT-T??????HHHH-HHHHHHHTTSS?SSEEEETTEEEEESS??HHHHHHHHH 1XG8|A PF07317.7_YcgR_seed 7 110 !Q:0,1|4,4|21,22|30,32|34,34|38,38|53,54|67,68|85,85|87,87|101,103|105,105|109,109 Q:2,3|5,20|23,29|33,33|35,37|39,52|55,66|69,84|86,86|88,100|104,104|106,108 --EE?SHHHHHHHHHHHHHTT??EEEEETT???E-EEE?EEEEETTTTEEEEE??BSGGGHHHHHTT??EEEEEEETTEEEEEEE?S?EEEEETTEEEEEE???S?EEE? 3KYF|A PF07319.6_DnaI_N_seed 37 99 !Q:0,2|5,5|7,11|13,15|31,31|45,46|64,64|67,67|72,73|77,78 Q:3,4|6,6|12,12|16,30|32,44|47,63|65,66|68,71|74,76|79,98 ???TT?S???-?S???HHHHHHHHHHHHHTT?HHHHHHHHHSTTT??HHHHHHTHHHHHHHHHS?SS?TTTS??TTS??SSTTEEEEEEEETTEEEEEE 2K7R|A PF07321.7_YscO_seed 12 166 !Q:1,4|67,68|77,80|155,165 Q:0,0|5,66|69,76|81,154 H----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT??HHHHHHHH----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGGT???------?? 4MH6|A PF07323.7_DUF1465_seed 26 180 !Q:0,9|32,36|47,47|51,54|88,88|96,119|146,179 Q:10,31|37,46|48,50|55,87|89,95|120,145 ??????????TTHHHHHHHHHHHHHHHHHHHT-----THHHHHHTTS?HHH----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSS?TTTTSSS??????????-----?????????HHHHHHHHHHHHHHHHHHHHHHHHHT?-???????------????????????-----?? 3CTW|B PF07336.6_DUF1470_seed 101 187 !Q:13,13|16,22|29,33|44,44|51,52|58,80|97,99|103,112|128,132|137,143|147,148|155,155|158,159|161,162|169,171|185,185 Q:0,12|14,15|23,28|34,43|45,50|53,57|81,96|100,102|113,127|133,136|144,146|149,154|156,157|160,160|163,168|172,184|186,186 HHHHHHHHHHHHS?EE-------ETTEEE?????HHHHHHHTTT?HHHHHH??THHHH-----------------------HHHHHHHHHHHHHHHH---HTT?---------HHHHHHHHHHHHHHS?-???EEEE------?TTS-?EEEESS?TT??H--HHHHHH---HHHHHHHHHHHTT?G 3H0N|A PF07338.8_DUF1471_seed 81 62 !Q:1,1|16,17|35,35|46,48 Q:0,0|2,15|18,34|36,45|49,61 T?EEEEEEEEEEESSS??SHHHHHHHHHHHHHHHT?SEEEEEEEEE---ETTEEEEEEEEEE 2JNA|A PF07345.6_DUF1476_seed 53 106 !Q:0,3|5,5|43,44|58,59|62,64|79,79|81,85|101,101 Q:4,4|6,42|45,57|60,61|65,78|80,80|86,100|102,105 ?-??S?TTTSSSTTTTTTSTHHHHHHHHHHHHHHHHHHHHHHT??TTHHHHHHTTSSS??TT???TTHHHHHHHHHHTT-T?---?HHHHHHHHHHTHHHH-HHHH 2LL0|A PF07348.7_Syd_seed 43 205 !Q:23,23|31,34|36,37|42,51|54,54|57,57|61,62|64,72|74,75|77,77|80,80|89,92|104,106|113,118|125,128|152,154|161,161|164,164|176,177|187,187|202,202 Q:0,22|24,30|35,35|38,41|52,53|55,56|58,60|63,63|73,73|76,76|78,79|81,88|93,103|107,112|119,124|129,151|155,160|162,163|165,175|178,186|188,201|203,204 HHHHHHHHHHHHHHHHHHHHSSS?EESTTTT----S??TTEE----------EE?SS?EEE??E---------E??S?SS?HHHHHHSS????HHHHHHTSSEE???EEEEET------TEEEEE????SHHHHHHHHHHHHHHHHHHHHTT???EEEEEE?SS-TTEEEEEETTT??EEEEETTSS?EEEEESSHHHHHHH?EE 3FFV|A PF07350.7_DUF1479_seed 29 649 !Q:2,4|24,28|55,59|61,61|72,82|102,102|126,145|149,153|174,174|179,187|189,189|195,196|202,207|211,212|215,289|291,292|298,298|300,300|307,307|311,312|322,323|325,325|328,328|330,331|335,338|344,363|365,366|376,376|378,378|383,383|387,387|389,389|392,392|407,479|482,483|486,487|491,491|494,495|499,500|503,504|509,509|512,514|516,516|519,519|527,528|532,533|537,538|540,542|544,565|568,569|571,571|592,594|598,598|600,604|606,618|622,622|625,627|631,634|637,641|648,648 Q:0,1|5,23|29,54|60,60|62,71|83,101|103,125|146,148|154,173|175,178|188,188|190,194|197,201|208,210|213,214|290,290|293,297|299,299|301,306|308,310|313,321|324,324|326,327|329,329|332,334|339,343|364,364|367,375|377,377|379,382|384,386|388,388|390,391|393,406|480,481|484,485|488,490|492,493|496,498|501,502|505,508|510,511|515,515|517,518|520,526|529,531|534,536|539,539|543,543|566,567|570,570|572,591|595,597|599,599|605,605|619,621|623,624|628,630|635,636|642,647 SS?-?SSHHHHHHHHHHHHHHHHS?----HHHHHHHHHHHHHHHHHHHHHHHHTT??--?S?EEEHHHHHHT???--------HHHHHHHHHHSEEEEETSS?HHHHHHHHHHHHHHHHHTTHHHH-?????????????--????EEE?????HHHHHHHTSHHHHHHHHHHH-TTSB--------?E-ETTEE??EEEEE??????EEE??TT??-------------------------------------------------------------------------B??EEEEE?S?STHHHH?HHH--HHHTHHHHT--S?GG-G??TTB?---TTGGG??????-------???????S??SEEEEEESS?B?TTSS?EEE?S?TT-HHHHHHHGGGSTTS?------------------------------------------------------------------------SS??TT??TTS?EE??TTT-?HH--HHTT?EE???B?TT?EEEEETT??EEE??BSS??S???E----------------------EE??B?EESHHHHHHHHHHHHHHHHT???TTS?S??---G-------------GGG?SS???GGG--??HH-----HHHTTT? 2DBI|A PF07352.7_Phage_Mu_Gam_seed 27 193 !Q:41,51|77,85|87,87|90,90|92,104|107,108|117,117|121,124|126,128|131,149|157,157|159,171|179,192 Q:0,40|52,76|86,86|88,89|91,91|105,106|109,116|118,120|125,125|129,130|150,156|158,158|172,178 SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----------HHHHHHHHHHHHHHHHHHHHTHHHH?--??????B?SS?B????????????-TT??HHHHHHHH-HHT----T?-?TT-----------????????HHHHTTS?H-------------HHHHHTT??????-??????? 2P2U|A PF07359.6_LEAP-2_seed 2 77 !Q:0,39|44,44|48,48|53,53|63,63|70,70|73,76 Q:40,43|45,47|49,52|54,62|64,69|71,72 -------------------------------------???TTSS?SSB?TTSB?SSGGGBTTS?EETTEE?SS???? 2L1Q|A PF07361.6_Cytochrom_B562_seed 25 107 !Q:0,0|19,21|42,45|52,52|83,83|104,106 Q:1,18|22,41|46,51|53,82|84,103 ?HHHHHHHHHHHHHHHHHH???HHHHHHHHHHHHHHHHHHTT??-?GGGTTS?TTSHHHHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHTTHHHHHHHHHH??? 2BC5|A PF07362.7_CcdA_seed 25 79 !Q:0,2|21,22|38,78 Q:3,20|23,37 ???EEEEEESTTTHHHHHHHT??SHHHHHHHHHHHHHH-------?????????????????????????????????? 2H3A|A PF07364.7_DUF1485_seed 60 336 !Q:0,1|9,10|15,16|18,18|20,20|26,34|48,48|50,50|63,77|80,81|85,88|96,96|100,100|102,102|121,127|135,135|137,139|143,143|169,169|172,175|182,182|188,190|193,195|212,213|215,215|218,219|227,227|229,230|233,237|259,264|270,272|275,277|280,280|290,294|319,323|325,325 Q:2,8|11,14|17,17|19,19|21,25|35,47|49,49|51,62|78,79|82,84|89,95|97,99|101,101|103,120|128,134|136,136|140,142|144,168|170,171|176,181|183,187|191,192|196,211|214,214|216,217|220,226|228,228|231,232|238,258|265,269|273,274|278,279|281,289|295,318|324,324|326,335 --EEEEEEE??EETT??S?B?GGGEE---------EEETHHHHHHHHT-S?SHHHHHHHHHHH---------------TT?-EEE----EEEEEEE?SEE?B?HHHHHHHHHHHHHHHHHS----?-?SEEEEEE?S???BSS?SSHHHHHHHHHHHHHTTTSEEEEEE?TT????HHHHHH?SEEEE???SS???HHHHHHHHHHHHHHTT--T?SS??EEEEEEE?B??BS?--??SSSSHHHHHHHHHHHHHTSTT----??EEEEE???TT???SS?SEEEEEEES-----SSSSHHHHHHHHHHHHHHTGGGSB?--??B?HHHHHHHHHT 3IUU|A PF07366.7_SnoaL_seed 29 153 !Q:11,14|17,18|20,23|39,41|43,46|49,49|73,75|85,85|99,100|102,102|106,110|112,118|133,133|144,144 Q:0,10|15,16|19,19|24,38|42,42|47,48|50,72|76,84|86,98|101,101|103,105|111,111|119,132|134,143|145,152 HHHHHHHHHTT----TT??H----HHHHHHEEEEEEETT??-T----TS?SSHHHHHHHHHHTHHHHEEEEEE---EEEEEEEET-TEEEEEEEEEEEE?-S?BTT-----B??--???EEEEEEEEEEEEET-TEEEEEEEEE?HHHHHHHH 2F98|A PF07367.6_FB_lectin_seed 14 158 !Q:0,1|5,9|16,17|21,22|31,31|36,36|44,45|49,49|58,58|66,66|70,71|90,90|92,93|95,95|97,98|108,112|114,115|117,117|119,119|127,127|134,134|138,138|147,147 Q:2,4|10,15|18,20|23,30|32,35|37,43|46,48|50,57|59,65|67,69|72,89|91,91|94,94|96,96|99,107|113,113|116,116|118,118|120,126|128,133|135,137|139,146|148,157 ??EEE-----EEEEEE??GGG??EEEEEEEE?SSTT?EEEEEET--TEE-EEEESSTT?EEEEEEE-ETT??EEEEEEEEETTEEEEEEE?S??T-T??HHHHGGGGS-----S--S?S?HHHHHTT?SEEEEE?TTS?EEEEEEEE?SSSEEEEEEE 1X99|A PF07369.6_DUF1488_seed 70 95 !Q:0,0|4,9|45,50|52,56|82,82|84,86|90,90|94,95 Q:1,3|10,44|51,51|57,81|83,83|87,89|91,93 ?EEE???--?EEETTTTEEEEEEEETTEEEEEEEEHHHHHHHHTS---???S-----HHHHHHHHHHTHHHHHHHHHHHHHT-T???TTS?EEE?- 2GPI|A PF07372.7_DUF1491_seed 53 116 !Q:0,1|18,18|25,27|31,32|53,53|55,62|65,65|70,70|72,77|94,94|97,97|105,105|108,113|115,115 Q:2,17|19,24|28,30|33,52|54,54|63,64|66,69|71,71|78,93|95,96|98,104|106,107|114,114 ??HHHHHHHHHHHHHHTT?EEEEEE???TTT??EEEEEEETTTTEEEEEEEEE?T--------TS?EEEE?S---???SSTHHHHHHHHHHHHH?TT?EEEEEEE-TT??????S? 4GOQ|A PF07385.7_DUF1498_seed 5 230 !Q:0,0|21,24|29,30|38,38|50,50|56,56|61,61|66,66|74,76|80,82|84,87|96,96|99,99|109,110|120,120|129,131|137,138|140,140|153,153|156,156|161,161|164,164|169,169|179,179|183,184|193,195|205,212|214,214|217,218|221,221|225,225 Q:1,20|25,28|31,37|39,49|51,55|57,60|62,65|67,73|77,79|83,83|88,95|97,98|100,108|111,119|121,128|132,136|139,139|141,152|154,155|157,160|162,163|165,168|170,178|180,182|185,192|196,204|213,213|215,216|219,220|222,224|226,229 ?BHHHHHHHHHHHHHHHHHTT????GGGG??HHHHHTS?TTTTHHHHHHT?EEEEE?TTSS?TTTB?EEEEEEE???TTS?--S????EEEEEEEE?BT?EEEEEEESS??EEEEEEEES?EEEEEEEB?--TTSSB??S?EEEEETTEEEEE?TT?EEEE?TT?EEEE?TTEEEEEEE?TTS??EEEEEEEE???TTTSEEESS????????B?SS??SS?BTT?GGGG 3MPB|A PF07392.7_P19Arf_N_seed 6 53 !Q:8,9|14,14|29,52 Q:0,7|10,13|15,28 HHHHHHHH--HHHS?STTHHHHHHHHHHT???????----------------- 1HN3|A PF07396.6_Porin_O_P_seed 34 474 !Q:6,6|16,18|27,27|32,32|48,54|66,67|75,92|101,101|103,105|109,110|118,123|129,129|133,133|138,141|149,160|164,166|183,183|190,199|209,209|228,229|243,243|247,251|253,255|258,258|263,263|267,269|274,279|281,286|321,332|335,337|353,357|366,370|372,372|374,379|382,382|400,401|403,404|407,409|411,411|414,414|428,428|430,432|450,451|454,460|473,473 Q:0,5|7,15|19,26|28,31|33,47|55,65|68,74|93,100|102,102|106,108|111,117|124,128|130,132|134,137|142,148|161,163|167,182|184,189|200,208|210,227|230,242|244,246|252,252|256,257|259,262|264,266|270,273|280,280|287,320|333,334|338,352|358,365|371,371|373,373|380,381|383,399|402,402|405,406|410,410|412,413|415,427|429,429|433,449|452,453|461,472 EEEEEE-EEEEEEEEE---ETTBSSSS?EEEE-EEEEEEEEEEEEETT-------TEEEEEEEETT??SSBTTTB?-----------------EEEEEEEE?T---TTT--SEEEEEE??????HHHHS?TTT?SSSS??--GGGGGSG------------GGG-??SEEEEEEEEEETTTEE-EEEEEE----------EEEEEBTTS?EEEEEEEEEEEEEEEETT--EEEEEEEEEEEEE?TTB?????B???TT?GGGS?SSB???GGGB??-???B????-?TTSEEEEEEEEEEEEEEETTEEEEEEEEEEEEEE-----------?TT???EEEEEEEEEEEEETT?????EETTTTEE?????S?T------TT?EEEEEEEEEEEEEEETT??S??SS---B?SS?EEEEEEEEEEEEE?S---SSEEEEEEEEEEEEESB??TT???----EEEEEEEEEEEE? 2O4V|A PF07404.6_TEBP_beta_seed 3 387 !Q:0,11|26,26|31,31|35,35|37,37|59,59|63,63|74,74|77,78|82,82|85,85|99,100|104,104|107,107|123,123|126,131|133,134|140,140|164,164|166,170|175,176|182,185|196,196|201,205|207,215|225,386 Q:12,25|27,30|32,34|36,36|38,58|60,62|64,73|75,76|79,81|83,84|86,98|101,103|105,106|108,122|124,125|132,132|135,139|141,163|165,165|171,174|177,181|186,195|197,200|206,206|216,224 ????????????HHHHHHHHHHTTTT?GGGS?GGG?S?EEEEEEEESSSEEEESSSEEE?EEE?HHHHHHHHTT?TT??GGG?TT?EEEEEEEEEEEEE??TTT?SS?BTTEEEEEEEEEEEE?TT??????S??EEGGG?HHHHHHHHHHHHHHHHHHHHHHS?S?????GGGG--SSGGG????GGGGEEESSS?SSSB?????S?????????HHHHHHHHH???????????????------?????????????????-????????????-???????????????????-???????????-???????????---???????????????????????????????????????????????????????????????? 1PH4|B PF07408.6_DUF1507_seed 14 91 !Q:0,4|31,38|65,65|84,90 Q:5,30|39,64|66,83 ?????HHHHHHHHHHHHHHHHHHHHHHHHHS????????SHHHHHHHHHHHHHHHHHHHHHTTSS?HHHHHHHHHHHHHHHHTT??????? 2ODM|A PF07411.7_DUF1508_seed 103 50 !Q:11,11|14,15|19,19|22,24|43,45|49,49 Q:0,10|12,13|16,18|20,21|25,42|46,48 ETTTEEEEEEE?TT??EEE-EB???SSHHHHHHHHHHHHHHTT???EEE? 3BID|A PF07412.7_Geminin_seed 7 210 !Q:0,105|107,108|173,209 Q:106,106|109,172 ?????????--?????????--------???????????????????????????????????????????????????-????--????-???????????????S??TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH???????????????------???????????????? 1UII|A PF07417.7_Crl_seed 17 134 !Q:0,4|6,6|10,10|19,19|23,23|27,30|42,42|46,46|50,51|76,76|80,80|84,88|113,113|116,116|121,121|124,128|132,133 Q:5,5|7,9|11,18|20,22|24,26|31,41|43,45|47,49|52,75|77,79|81,83|89,112|114,115|117,120|122,123|129,131 ?????S?HHH-HHHHHHTT?TTB?GGG????EEEEEEEEEES?TTS?SSS??EEEEEEEEEEETTEEEEEEEEEEE?TTS?EES?????HHHHHHHHHHHHHHHHHHHHHHHH-TT?EEEE?GG-----GGG?? 3RPJ|A PF07419.7_PilM_seed 13 149 !Q:0,27|53,53|60,60|62,64|70,75|78,80|95,96|98,99|112,115|125,125|129,129|131,136|140,140|148,148 Q:28,52|54,59|61,61|65,69|76,77|81,94|97,97|100,111|116,124|126,128|130,130|137,139|141,147 -------?------------????????HHHHHHHHHHHHHHHHHHHHHHHHH?GGGGGG?B???HHHHT???--?SS--?EEEEETTEEEEEEE??T--THHHHHHHHTTT????EEEETTEEE?TTS?B??????TTS?SSEEEEE? 3HG9|A PF07422.8_s48_45_seed 83 296 !Q:0,0|4,7|11,36|38,38|41,63|70,71|78,78|80,80|86,86|93,97|101,102|107,108|111,164|172,172|176,180|182,205|209,209|211,212|217,227|232,256|268,270|272,285|293,293|296,296 Q:1,3|8,10|37,37|39,40|64,69|72,77|79,79|81,85|87,92|98,100|103,106|109,110|165,171|173,175|181,181|206,208|210,210|213,216|228,231|257,267|271,271|286,292|294,295 ?EEE----EES--------------------------S?TT----------------------?SSEEEE??TTTTTS-S?SSSSS?EEEEEE?---?SSS?-EEEE??TT------------------------------------------------------SEEEEEE?SSS?----B-----------------------?TTS?B??STTT??--------?EEEE-------------------------EETTTTEEEEE??-S????--------??EEEEEEE?TT- 2LOE|A PF07425.6_Pardaxin_seed 3 33 !Q:0,0|32,32 Q:1,31 ?TTTHHHHHHHSSSTHHHHHHHHHHHSTTGGG? 2KNS|A PF07428.6_Tri3_seed 3 415 !Q:1,5|11,11|14,14|19,19|25,26|34,34|44,44|54,54|56,56|59,62|81,81|86,86|90,91|96,96|102,103|122,122|124,125|141,147|149,149|163,165|168,168|177,177|181,182|201,205|210,213|222,224|232,232|236,237|258,259|262,268|276,277|293,293|296,297|314,320|323,324|333,333|338,338|345,346|348,349|358,359|364,366|370,370|395,395 Q:0,0|6,10|12,13|15,18|20,24|27,33|35,43|45,53|55,55|57,58|63,80|82,85|87,89|92,95|97,101|104,121|123,123|126,140|148,148|150,162|166,167|169,176|178,180|183,200|206,209|214,221|225,231|233,235|238,257|260,261|269,275|278,292|294,295|298,313|321,322|325,332|334,337|339,344|347,347|350,357|360,363|367,369|371,394|396,414 S?????GGGGS?EE?STTS?EEEEE??THHHHHT?HHHHTTTTT?EEEEEEEEE?S?TT????HHHHHHHHHHHHHHHHHH?GGGG?EEE??SSSS?EEEEE??SSHHHHHHHHHHHEEEEE?S??HHHHHHHHHHHHHHT???????S?EEEEEESSSSTTS???TT?EEEEEEEE?GGG??HHHHHHHHHHHHHHGGGT?????GGGS????TTTTGGGS???TGGGBSS?GGG??HHHHHHHHHHHHHHHHHHTS??EE???????EEEEEEE??HHHHHHHHHHHHHHT?TT??HHHHHHHHHHHHHHHH???????TT??EEEEEEEE?GGGB?HHHHTS??S??EEEEEEEE??GGGG???TTS?HHHHHHHHHHHHHHHHHHHHHHHT?TTHHHHHHHHHHHHHHHHH 3FP0|A PF07434.6_CblD_seed 5 394 !Q:0,22|24,27|42,47|59,59|62,63|65,65|73,73|78,78|82,82|85,86|88,89|94,95|98,98|111,112|126,126|129,147|149,149|152,156|158,158|162,164|173,173|180,180|183,183|200,200|202,204|218,218|220,221|224,224|228,228|231,231|234,235|240,242|246,246|263,263|268,269|278,278|280,285|289,289|294,297|320,322|325,326|334,337|341,344|349,351|353,353|366,368|373,374|389,390 Q:23,23|28,41|48,58|60,61|64,64|66,72|74,77|79,81|83,84|87,87|90,93|96,97|99,110|113,125|127,128|148,148|150,151|157,157|159,161|165,172|174,179|181,182|184,199|201,201|205,217|219,219|222,223|225,227|229,230|232,233|236,239|243,245|247,262|264,267|270,277|279,279|286,288|290,293|298,319|323,324|327,333|338,340|345,348|352,352|354,365|369,372|375,388|391,393 ---------------------??B????EEEEEEEEEEETTS????--EEEEEEEEEEE?SS??T-TSSEEEE?SBSS?GGG?BS??S??SSSS??BS?EEEEEEEEETTT??EEEEEEEEEEEEE?SS?????-------------?B?TT?????B-TTB???EEEEEEEE?TTGGGG?SS?EEEEEEEEEEEEETTS?E---EEEEEEEEEEEEE?G--GG?EEE?TT?SS-?EEEE???EEE-ETTEEEEEEEEEEEEE?SSTT??SEEEEEEE?S---???SSS?EEEE----ETTEEEEEEEEEEEEEETTEEE???TT??EEEESTT-???EEE????SSSS???S?EEEEEEEEEEEE---EEES??SEEEEEEEEEEEEE??SSS 3VAC|A PF07435.6_YycH_seed 6 487 !Q:0,52|54,57|63,64|70,71|80,82|104,104|108,109|112,113|122,122|126,127|143,143|149,152|154,155|159,159|169,171|174,174|195,195|213,213|223,227|237,237|242,251|262,262|266,269|271,279|283,283|286,286|300,303|305,312|315,316|333,334|337,339|346,347|350,350|365,366|370,371|374,375|382,382|394,405|410,411|422,423|426,426|439,456|475,486 Q:53,53|58,62|65,69|72,79|83,103|105,107|110,111|114,121|123,125|128,142|144,148|153,153|156,158|160,168|172,173|175,194|196,212|214,222|228,236|238,241|252,261|263,265|270,270|280,282|284,285|287,299|304,304|313,314|317,332|335,336|340,345|348,349|351,364|367,369|372,373|376,381|383,393|406,409|412,421|424,425|427,438|457,474 ------------------------------?-----?????????------??S????HHHHS??SEEEE--EETTEEEE???HHHHHHHHHHGGGSEEEEEEE?GGG??HH--HHHHHHTT?TTS??EEEEEEEEEEEHHHH-HHHHT????S--STT?EEEEEEEES???SS-SEEEEEEETTTTEEEEEEEE?SSHHHHHHHHHHHGGGS?BEEEEEETT-----TEEEEEESS?EEEE??????????HHHHHHHHSS?GGG?---B?????????EEE?SS?EEEEETTTTEEEE----E?-??????SS??HHHHHHHHHHHHHHTT??SS?--EEEEEE-?TT?EEEEEEEETTEEEE??SSS??SS??EEEEEE?SSSEEEEEEES????-???????EEEE??SHHHHHHHHT??SS?GGGEEEEEEEEE?????-?????---????EEEEEEEETTEEEEESTT???????????? 2FGT|A PF07445.7_priB_priC_seed 21 199 !Q:21,33|36,37|42,42|45,46|70,70|72,73|98,98|101,198 Q:0,20|34,35|38,41|43,44|47,69|71,71|74,97|99,100 HHHHHHHHHHHHHHTSTTTTT?---------???TT??TTTS?SS??SHHHHHHHHHHHHHHHHHHGGGT?H--HHHHHHHHHHHHHHHHHHHHHHHH?SS??------------------------------------------------------------------------------------------------ 2RT6|A PF07447.7_VP40_seed 2 295 !Q:0,49|51,52|55,55|58,59|64,64|68,69|101,101|106,106|125,126|130,130|139,141|144,144|163,163|166,168|170,171|185,186|190,203|213,214|217,232|246,246|262,263|272,277|280,280|282,282|288,289|292,295 Q:50,50|53,54|56,57|60,63|65,67|70,100|102,105|107,124|127,129|131,138|142,143|145,162|164,165|169,169|172,184|187,189|204,212|215,216|233,245|247,261|264,271|278,279|281,281|283,287|290,291 ??????????????????????????????????????????????????B??EE?TT??GGGT?STT??EEEEEEEEEEEEETTEEEEEEEEEEEEEEEE?SSSS?HHHHHHHHHSSEEEEEEE??SSS?EEEEEEES???TT?SSHHHHHSEEEEEHHHHS?SS???S??EEEEEEEEEEEEE??TTB??????????????EEEESSTTS??EE????????????????HHHHHHHHHHGGG?EEEEEEGGGTEEEEE??HHHHHHHH??????SS?S?EEEEE??TT???- 3TCQ|A PF07449.6_HyaE_seed 9 114 !Q:8,8|13,15|26,29|37,43|47,50|61,62|64,66|71,73|86,86|90,91|105,106 Q:0,7|9,12|16,25|30,36|44,46|51,60|63,63|67,70|74,85|87,89|92,104|107,113 HHHHHHTT-TEEE??-STTHHHHHHH----HSEEEEE???????SSS????THHHHHHHHH??S???EEEE?-?STHHHHHHHHTT?TTS??EEEEETTEEEEEE??SSTTHHH 2YJ7|A PF07451.6_SpoVAD_seed 41 354 !Q:6,7|9,10|20,20|36,36|67,68|71,72|74,74|97,99|104,105|126,126|136,136|142,163|172,175|178,195|197,197|205,208|210,211|213,215|218,218|240,241|245,245|253,253|266,266|271,273|277,277|287,302|320,320|331,333|341,344 Q:0,5|8,8|11,19|21,35|37,66|69,70|73,73|75,96|100,103|106,125|127,135|137,141|164,171|176,177|196,196|198,204|209,209|212,212|216,217|219,239|242,244|246,252|254,265|267,270|274,276|278,286|303,319|321,330|334,340|345,353 TTTEEE??S??EEEEEEEEE?HHHHHSTTGGGSSEE?SSTTTTSSSHHHHHHHHHHHHHHHHHHTTT??GG--G?SEEEEEESSSSSTTHHHHHHHH???EEEB??STTHHHHHHHHHHHHHHTTS?SEEEEEEEE?GGGTT??????????????????????EEEEEEEE----SS??----------------S-EEEEEEE????B??S???TT?HHHHHHHHHHHHHHHHHHHHT??GGG?SEEEEES?HHHHHHHHHHHH-HHTT???GGG-EEEGGGTSS???-????????????HHHHHHHTHHHHHHTTS?SEEEEEEEEE???HHHHHTT????EEEEEEEEE 3LM6|A PF07455.6_Psu_seed 5 197 !Q:0,4|39,39|43,47|113,114|139,144|146,152|163,163|166,167|175,175|177,179|196,197 Q:5,38|40,42|48,112|115,138|145,145|153,162|164,165|168,174|176,176|180,195 ???-?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HSS???--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHTTGGG??HHHHHHHHHHHHHHHHHHHHHHHT------T???????TTTHHHHHHH?SS??HHHHHHH?S???HHHHHHHHHHHHHHHH?- 3RX6|A PF07460.6_NUMOD3_seed 25 45 !Q:2,5|15,26|31,33|36,41|45,45 Q:0,1|6,14|27,30|34,35|42,44 TT????HHHHHHHHH------------HHTT???TT??---?EEE- 1I3J|A PF07461.6_NADase_NGA_seed 2 446 !Q:0,195|207,208|212,212|236,236|238,238|249,254|269,269|275,275|285,285|289,289|298,298|313,313|317,317|319,320|330,331|338,339|345,345|357,358|360,362|368,369|372,373|377,380|383,383|387,390|394,394|398,398|401,402|415,416|421,421|425,425|428,429|433,433|442,446 Q:196,206|209,211|213,235|237,237|239,248|255,268|270,274|276,284|286,288|290,297|299,312|314,316|318,318|321,329|332,337|340,344|346,356|359,359|363,367|370,371|374,376|381,382|384,386|391,393|395,397|399,400|403,414|417,420|422,424|426,427|430,432|434,441 ---------------------------------------------------------------------??---------------------------------------------------------------------------------?????---------------------------------??????HHHHHHHHHHH??TTS?HHHHHHHHHTHHHHHHHHHHTTS?S?HHHHHHHHHH??????HHHHHHHHHHHHHH?EEEEE?HHHHHHHHH?GGG?SEESSGGG?EEEEEHHHHHHHHB?TTS?B??HHHHHHHTT??TTTTTT??EEEEE?HHHHHHHHHHT??B???TTSTT??TT??TTT????TT?GGG????EEE?EEE?TT??HHHHHHHHHHHS??EEES?EEE?TT??EEE?SSEEEEEE????- 3PNT|A PF07463.6_NUMOD4_seed 55 75 !Q:0,1|5,5|7,8|10,10|15,16|24,24|28,45|49,49|53,54|56,58|60,60|62,66|72,72 Q:2,4|6,6|9,9|11,14|17,23|25,27|46,48|50,52|55,55|59,59|61,61|67,71|73,74 ??EEE?T--T-STTT--EEEETTS?EEE------------------SSS?SEE??B??-S-S??--?EEEEE-ET 1U3E|M PF07464.6_ApoLp-III_seed 8 160 !Q:22,25|28,28|58,58|83,83|91,91|119,121|124,124|138,140|158,159 Q:0,21|26,27|29,57|59,82|84,90|92,118|122,123|125,137|141,157 HHHHHHHHHHHHHHHHHHHTSS--??SS?SSHHHHHHHHHHHHHHHHHHHHHHHHHTT?SSTHHHHHHHHHHHHHHHHHGGGG?SHHHHHT?SSSHHHHHHHHHHHHHHHHHHHHHHHS???SS?GGGHHHHHHHHHH---HHHHHHHHHHHHHHHTT?? 1EQ1|A PF07465.8_PsaM_seed 40 29 !Q:0,1|27,28 Q:2,26 ??HHHHHHHHHHHHHHHHHHHHHHHHH?? 1JB0|M PF07467.6_BLIP_seed 3 193 !Q:0,29|31,32|40,40|43,44|53,53|56,56|60,60|93,94|105,106|109,110|112,112|119,120|123,123|133,133|144,144|150,150|153,153|165,166|170,171|192,192 Q:30,30|33,39|41,42|45,52|54,55|57,59|61,92|95,104|107,108|111,111|113,118|121,122|124,132|134,143|145,149|151,152|154,164|167,169|172,191 ----------------------------??S??HHHHHHS?TT??HHHHHHHH?GG-GEE?SGGGTTSEEEEEEEETTEEEEEEEEESSSSTT??EEEEEEESSS??SB??B?HHHHHH??TT?BHHHHHHHH?TBSEEEEEEE?TTTTS?TT?EEEEEEEBTTT??SSS??SSEEEEEEETTEEEEEEEES? 1S0W|C PF07468.6_Agglutinin_seed 2 154 !Q:0,1|3,3|20,21|39,39|42,43|49,49|55,55|64,65|74,75|84,87|93,95|105,105|124,125|129,131|141,142|145,145|148,148 Q:2,2|4,19|22,38|40,41|44,48|50,54|56,63|66,73|76,83|88,92|96,104|106,123|126,128|132,140|143,144|146,147|149,153 ??S?SEEEEEETTTTEEEEE??SSSTTTTBEEEEESSTT?TT??EEEEE?SSSTT?EEEEETTT??EEEESSTT??BEEEEESS????TTSTT???EEEEESSTT?TTEEEEEETTTTEEEEEE??STT-??SEEEEEESS??TT?TT?EEEEE 1JLY|A PF07470.8_Glyco_hydro_88_seed 19 494 !Q:12,16|20,23|29,39|49,49|52,52|59,60|63,66|74,83|90,90|93,104|106,111|114,114|125,128|131,134|140,142|155,155|161,161|163,163|167,167|169,169|171,176|185,197|212,215|221,221|223,224|241,257|260,260|265,265|267,267|272,274|277,278|283,283|287,287|289,289|291,292|311,316|318,318|320,320|322,322|337,337|340,340|346,346|351,352|358,358|364,365|367,367|383,394|399,402|404,405|425,426|428,433|435,435|439,439|443,444|447,447|449,450|452,462|470,470|475,475 Q:0,11|17,19|24,28|40,48|50,51|53,58|61,62|67,73|84,89|91,92|105,105|112,113|115,124|129,130|135,139|143,154|156,160|162,162|164,166|168,168|170,170|177,184|198,211|216,220|222,222|225,240|258,259|261,264|266,266|268,271|275,276|279,282|284,286|288,288|290,290|293,310|317,317|319,319|321,321|323,336|338,339|341,345|347,350|353,357|359,363|366,366|368,382|395,398|403,403|406,424|427,427|434,434|436,438|440,442|445,446|448,448|451,451|463,469|471,474|476,493 HHHHHHHHHHHH??---TTT----SSSTT???--------HHHHHHHHH-HH-HHHHHH??HH----HHHHHHH----------HHHHHB?TT??----------B???---TT?GGGTGGGGGH----HH----HHHHH?-?HHHHHHHHHHHG-GGGTS?B?TTS?B?S-----?TTSTTEEE-------------THHHHHHHHHHHHH----HHHHT?T--HHHHHHHHHHHHHHHH-----------------HB?TTTS?B?SEEE---TT??STTS?TTT?B?S??BHHHHHHHHHHHHHHGGG------S?T-T?HHHHHHHHHHHHHH-HH-HHTTS?TTTS??BSBTT?TTSTT??B?HHHHHHHHHHHHHHH------------HHTS----S-?GGGHHHHHHHHHHHHHHHE--E------E?TTS?EEE??EE?S??S??---------HHHHHTS?EESS?HHHHHHHHHHHHHHHHHH 3ANJ|A PF07471.7_Phage_Nu1_seed 11 166 !Q:0,0|13,14|26,28|31,33|37,38|66,165 Q:1,12|15,25|29,30|34,36|39,65 ?EEEHHHHHHHTT??HHHHHHHTTTT???SS???SSS??EEEHHHHHHHHTTTGGGGGGGGGGSSS??-------------------------------------------------------------------------------------------------- 1J9I|A PF07472.6_PA-IIL_seed 12 121 !Q:2,3|6,6|18,18|33,34|54,54|58,58|71,71|83,90|105,109|119,120 Q:0,1|4,5|7,17|19,32|35,53|55,57|59,70|72,82|91,104|110,118 EE??TT?EEEEEEEEEEE-EEEEEEEEETTEEE--EEEEEEEEEEEEEEEEEEE?TTT?EEEEEEEETTEE?EEEEEEEEETT--------TEEEEEEEEESSSS??--?BSEEEEEEE?? 2VNV|A PF07473.6_Toxin_11_seed 2 28 !Q:0,2|4,5|10,10|25,27 Q:3,3|6,9|11,24 ???B??SSSS?SSSSEEEETTEEEE??- 1IXT|A PF07474.7_G2F_seed 5 212 !Q:2,2|19,19|21,23|25,25|42,42|50,50|52,53|63,63|75,75|78,79|82,84|107,109|118,118|120,120|123,127|129,129|132,132|141,144|147,147|151,153|162,162|178,179|184,187|200,203|205,206|209,211 Q:0,1|3,18|20,20|24,24|26,41|43,49|51,51|54,62|64,74|76,77|80,81|85,106|110,117|119,119|121,122|128,128|130,131|133,140|145,146|148,150|154,161|163,177|180,183|188,199|204,204|207,208 TT?EEEEEEEEEEEEEETT?S---S?EEEEEEEEEEEEETTT?EEEEEEE-S??HHHHGGGTT?THHHHHHHHHT?EE?-TT???HHHHHTTEEEEEEEEEETTSSS--?EEEEEEEE?B?TT-----S?EE?EEEEEEEE????TT?EEE???EEEEEEEE-TTEEEEEEEEEEEEE??SSTT????EEEEEEEEEEEE????S??SS??? 1GL4|A PF07475.7_Hpr_kinase_C_seed 81 178 !Q:0,5|24,24|42,43|54,56|60,62|66,68|90,90|95,95|100,101|108,109|111,128|130,131|135,136|142,143|146,147|166,168 Q:6,23|25,41|44,53|57,59|63,65|69,89|91,94|96,99|102,107|110,110|129,129|132,134|137,141|144,145|148,165|169,177 ??????EEEESEEEEETTEEEEEE?STTSSHHHHHHHHHHTT?-EEEESSEEEE???SSS?-?EEE-??GGGTTEEEETTTEEEEHHHHH?GGGB?SEEE??EEEEEE??S??--?????????-????B??TTT??EEEEE??SS??HHHHHHHHHHHHHHHHTT-??HHHHHHHHH 1JB1|A PF07476.6_MAAL_C_seed 14 253 !Q:1,7|10,12|15,15|28,28|34,38|44,44|65,65|70,72|78,78|89,91|110,110|115,115|118,119|141,142|148,148|151,152|165,165|172,172|194,194|199,201|205,205|221,221|226,227 Q:0,0|8,9|13,14|16,27|29,33|39,43|45,64|66,69|73,77|79,88|92,109|111,114|116,117|120,140|143,147|149,150|153,164|166,171|173,193|195,198|202,204|206,220|222,225|228,252 T???????EE???TT?TTHHHHHHHHTT?SEEEE?????IIIII?TTSHHHHHHHHHHHHHHHHH?SSTT???EEEEE?TTHHHHHTTT--?HHHHHHHHHHHHHHHTTS?EEEE?SB??SSHHHHHHHHHHHHHHHHHHT??EEEEE?TT??SHHHHHHHHHTT?SSEEEE?TGGGSSTHHHHHHHHHHHHTT?EEEE???TTS?HHHHHHHHHHHHHHT?SEEE??SSSSSHHHHHHHHHHHHHHHHHHHT 1TE6|A PF07477.7_Glyco_hydro_67C_seed 38 266 !Q:18,18|22,22|36,46|56,67|80,80|83,83|86,89|91,91|94,97|99,101|104,104|113,118|121,128|133,137|142,146|152,152|166,166|174,175|180,180|182,182|186,186|218,218|252,257|260,265 Q:0,17|19,21|23,35|47,55|68,79|81,82|84,85|90,90|92,93|98,98|102,103|105,112|119,120|129,132|138,141|147,151|153,165|167,173|176,179|181,181|183,185|187,217|219,251|258,259 SSSGGGHHHHHHHHHHHH?TTS?HHHHHHHHHHHHH-------??-?HHHHHHHHH------------HHHHHHHHHHHT-SS?TT????B?TT----T-??SB?TTTTTTSS------SS?--?????SSEE?????TTTS??---GGGGS?HHHHHHHHSTTTS?GGGHHHH??EETT?B?TTS?BHHHHHHHHHHHHHHHHHHHHHHHHTTTTSS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?--???TT????-? 1K9E|A PF07478.8_Dala_Dala_lig_C_seed 18 222 !Q:6,7|9,10|15,15|22,29|38,38|48,49|54,54|74,74|76,76|82,85|96,97|101,102|112,113|115,120|122,132|138,138|144,144|147,147|167,168|178,179|182,183|193,195|199,199|210,211 Q:0,5|8,8|11,14|16,21|30,37|39,47|50,53|55,73|75,75|77,81|86,95|98,100|103,111|114,114|121,121|133,137|139,143|145,146|148,166|169,177|180,181|184,192|196,198|200,209|212,221 HHHHTT??B??EEEE?TTTTTS??------HHHHHHHH?SSEEEEESB??TTTT?EEESSHHHHHHHHHHHTTT?S?EEEEE??-?SEEEEEEEEE--SSS-?EEEEEEEEE??T------T????????---SGGGG?EEESS?SS?HHHHHHHHHHHHHHHHHTT??EEEEEEEEE-?TT??EEEEEEESS???STT?HHHHHHHTTT??HHHHHHHHHH 3ORQ|A PF07479.9_NAD_Gly3P_dh_C_seed 27 185 !Q:1,1|25,30|33,39|62,62|65,68|88,90|103,107|116,120|124,127|144,157|161,161|174,176 Q:0,0|2,24|31,32|40,61|63,64|69,87|91,102|108,115|121,123|128,143|158,160|162,173|177,184 S?HHHHHHHHHHHHHHHHHHHHHHH------TT??-----HHHHHHHHHHHHHHHHHHHHHH?SS??-?GGGGGSTTTHHHHHHHHHH--?HHHHHHHHHHHH?--??HHHHHHHH-----STT????HHHHHHHHHHHHHTTT?-------------GGG?HHHHHHHHHHHT???GGGHHHHH 1EVY|A PF07484.7_Collar_seed 181 93 !Q:1,1|9,14|16,24|26,34|37,40|48,48|50,51|55,57|63,65|73,73|75,78|84,85|87,87|90,92 Q:0,0|2,8|15,15|25,25|35,36|41,47|49,49|52,54|58,62|66,72|74,74|79,83|86,86|88,89 T?EEEESSS------S?--------S---------ST----TEEESBS?B??TTT--?HHHHH---HTTTTTS-B---?SSSBB??B?TT??? 1PDI|A PF07486.7_Hydrolase_2_seed 170 175 !Q:3,3|19,19|21,26|31,31|33,34|44,50|52,52|54,54|58,58|61,83|85,85|87,87|89,89|91,100|102,105|110,112|118,118|120,121|124,128|133,134|137,138|140,141|145,150|152,154|158,159|162,162|174,174 Q:0,2|4,18|20,20|27,30|32,32|35,43|51,51|53,53|55,57|59,60|84,84|86,86|88,88|90,90|101,101|106,109|113,117|119,119|122,123|129,132|135,136|139,139|142,144|151,151|155,157|160,161|163,173 TTS?HHHHHHHHHHHHHHH-H------STTS?S--SHHHHHHST-------T-S?HHH-HH-----------------------T?S-S-S-------???H----HHHH---HHHHH-H--TT?---?TTSS??EE--E?-TTT--?-??H---HHH--HS?EEEEETTEEEE? 4F55|A PF07487.8_SopE_GEF_seed 2 165 !Q:1,3|27,27|59,60|77,78|82,82|85,85|91,91|94,94|108,108|142,144|163,164 Q:0,0|4,26|28,58|61,76|79,81|83,84|86,90|92,93|95,107|109,141|145,162 S???SSSHHHHHHHHHHHHTHHHHHHH?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT??HHHHHHHHHHHHHHTT??EEE?SS?EEETT?SS?TTHHHHHHHHHHH?HHHHSSHHHHHHHHHHHHHHHHHHHGGGGTSSS???HHHHHHHHHHHHHHHHHS?? 1R6E|A PF07488.7_Glyco_hydro_67M_seed 37 397 !Q:7,13|16,16|18,26|30,31|33,33|40,45|47,47|50,55|57,57|61,62|66,66|72,90|94,94|96,97|112,113|117,117|119,119|122,123|126,128|153,153|160,160|167,170|173,177|179,181|200,200|203,203|206,207|212,220|224,224|227,228|245,245|251,260|263,264|267,268|283,283|285,285|299,300|303,306|312,312|316,316|323,323|325,325|334,337|343,345|350,350|352,353|359,360|369,370|373,376|379,379|382,382|388,391|397,397 Q:0,6|14,15|17,17|27,29|32,32|34,39|46,46|48,49|56,56|58,60|63,65|67,71|91,93|95,95|98,111|114,116|118,118|120,121|124,125|129,152|154,159|161,166|171,172|178,178|182,199|201,202|204,205|208,211|221,223|225,226|229,244|246,250|261,262|265,266|269,282|284,284|286,298|301,302|307,311|313,315|317,322|324,324|326,333|338,342|346,349|351,351|354,358|361,368|371,372|377,378|380,381|383,387|392,396 HHHHHTT?----??TT?E---------EEE??S?SEEEEE??----B?TT------S?BTT??SSS?SSEET-------------------TEE?S??HHHHHHHHHHHHTT??EEE?S?SS??HH---HHGGGSTTTHHHHHHHHHHHHHTT?EEEEEE?TTHHHH----TT?---?S???TTSHHHHHHHHHHHHHHH-HH?TT??EEEE?????????GGG-GT??HHHHHHHHHHHHGGGT?EEEEE???????-??TT-?TT??HHHHHHHHHGGGTT?S?TTEEEEEESSSSS??SS????TTTTS?TTS?EEEEEE?S?TTTTTTTS????HHHHH---HHHT?B??TTSSS-?BHHHHHTS--TT----TT?SS?EEEEE????SSTTS- 1K9E|A PF07494.6_Reg_prop_seed 668 31 !Q:0,3|5,5|9,10|15,18|21,23 Q:4,4|6,8|11,14|19,20|24,30 ????S-SEE--EEEE---?TT?-?EEEEETT 3VA6|A PF07495.8_Y_Y_Y_seed 79 78 !Q:0,0|6,7|17,18|21,21|27,39|44,44|46,47|59,59|62,63|65,65|68,69|77,77 Q:1,5|8,16|19,20|22,26|40,43|45,45|48,58|60,61|64,64|66,67|70,76 ?TTTTT??EEEEEEETT?-SS?EEESS??-----------EEEE?S??SEEEEEEEEEE?TT??B?SS?-EEEEEEE? 3VA6|A PF07496.10_zf-CW_seed 52 64 !Q:0,1|5,5|11,12|16,19|22,23|25,26|30,30|32,33|35,36|40,40|42,47|51,54|59,63 Q:2,4|6,10|13,15|20,21|24,24|27,29|31,31|34,34|37,39|41,41|48,50|55,58 ??EEE?SSTTT??EEE??--SS??T--TTS?T--T??GGG?S-----?GGG---?SSSS????? 4FWJ|A PF07497.7_Rho_RNA_bind_seed 16 79 !Q:0,0|8,8|10,10|14,14|19,19|25,27|30,30|34,34|43,44|47,47|55,57|60,61|75,75|78,78 Q:1,7|9,9|11,13|15,18|20,24|28,29|31,33|35,42|45,46|48,54|58,59|62,74|76,77 ?EEEEEEE-E?TTS?EEEE?GGGTT???TT?EEE?HHHHHHHT??TT?EEEEEEE???TT??SEEEEEEEEESSS?TT? 1PV4|A PF07498.7_Rho_N_seed 139 50 !Q:2,2|6,6|16,16|20,21|23,26|32,32 Q:0,1|3,5|7,15|17,19|22,22|27,31|33,49 HH-HHS?HHHHHHHHH-HTT?-T----TGGGS?HHHHHHHHHHGGGSSSS 1PV4|A PF07499.8_RuvA_C_seed 100 55 !Q:0,0|14,15|27,32|35,40|44,44|54,54 Q:1,13|16,26|33,34|41,43|45,53 ?HHHHHHHHHHHHT??HHHHHHHHHHS?----?SS??----HHH-HHHHHHHTT? 1IXS|A PF07500.9_TFIIS_M_seed 84 184 !Q:0,1|10,10|21,22|26,26|29,42|45,46|57,85|92,95|97,100|103,105|121,121|137,137|141,151|156,156|162,162|168,168|170,179|182,183 Q:2,9|11,20|23,25|27,28|43,44|47,56|86,91|96,96|101,102|106,120|122,136|138,140|152,155|157,161|163,167|169,169|180,181 ??STTHHHHH-HHHHHHHHSS--THH-HH--------------HT??HHHHHHHHHH-----------------------------HHHHHH----T?---TT---THHHHHHHHHHHHHH?SSSSHHHHHHHTTSS?HHH-----------HHHS?HHHHH?TTTTT?S----------SS?? 3PO3|S PF07501.7_G5_seed 140 86 !Q:0,2|12,13|15,17|23,23|27,27|30,31|37,38|40,40|52,52|56,57|62,65|72,74|76,76|82,83 Q:3,11|14,14|18,22|24,26|28,29|32,36|39,39|41,51|53,55|58,61|66,71|75,75|77,81|84,85 ???EEEEEEEEE--E???EEEEE?TTS?TT?-EEEEE??B?EEEEEEEEEEE?TTT??EEEE?-??EEEEEE-??B?EEEEE??EE 3EO5|A PF07503.7_zf-HYPF_seed 185 39 !Q:0,1|7,7|11,11|14,15|17,17|22,22|25,27|32,32|38,38 Q:2,6|8,10|12,13|16,16|18,21|23,24|28,31|33,37 ??HHHHH-HHT?TT--S-TTTT?TT???TTSB?SGGGB? 3TTD|A PF07504.8_FTP_seed 142 57 !Q:4,6|9,9|12,12|16,17|31,31|39,39|43,43|54,56 Q:0,3|7,8|10,11|13,15|18,30|32,38|40,42|44,53 EEEE--?TT?EE?TTS?-EEEEEEEEETTEE-EEEEEEE-EEE?TTSSEEEEEE??? 3NQY|A PF07508.8_Recombinase_seed 73 206 !Q:9,9|15,21|23,24|27,28|41,82|87,93|99,99|103,104|106,133|144,170|173,184|187,188|191,191 Q:0,8|10,14|22,22|25,26|29,40|83,86|94,98|100,102|105,105|134,143|171,172|185,186|189,190|192,205 HHHHHHHHH-HHHHH-------H--HH??HHHHHHHHHHTT?---???----------------------------------?HHHH-------HHHTS?GGG--G----------------------------TEEEETTTEE---------------------------EE?-----------SS??SS?HHHHHHHHHHHHHH 4KIS|A PF07514.6_TraI_2_seed 21 368 !Q:1,1|5,6|12,12|29,30|34,40|59,73|94,94|97,98|102,109|133,133|135,139|141,142|145,146|150,151|158,162|169,170|176,181|194,194|204,204|208,208|219,234|241,241|247,249|251,251|253,265|267,268|286,286|290,290|292,292|298,298|302,304|309,309|314,314|321,322|329,330|333,334|336,343|359,363|366,366 Q:0,0|2,4|7,11|13,28|31,33|41,58|74,93|95,96|99,101|110,132|134,134|140,140|143,144|147,149|152,157|163,168|171,175|182,193|195,203|205,207|209,218|235,240|242,246|250,250|252,252|266,266|269,285|287,289|291,291|293,297|299,301|305,308|310,313|315,320|323,328|331,332|335,335|344,358|364,365|367,367 T?EEE??HHHHT?SHHHHHHHHHHHHHHT??HHH-------HHHHTHHHHHHHHHHHTT??-------------SSTHHHHHHHHHHHHHHHHH?TT??HHH--------HHHHHHHHHHTTTTHHHHSEEEE?T-----T??EE??GGG??GGGSTT??---EEEEEE??GGGGG------GHHHHHHHHHHS?HHHHHHHHT-SHH-HHHHHHHHTT?---???-----????TTHHHH-HHHHT???S?S????-?---????B??GGGHHHHHHHHHHHHHH-HTT?S?BSSSS?SEE---EETT-EEEE-ETTTHH--HHHHHH?-TT--S???-----HHHHHHHHHHHTTTT-?---TT?T 3KQ5|A PF07515.6_DUF1528_seed 40 131 !Q:1,1|7,7|31,52|65,66|68,69|71,78|82,83|95,95|113,125 Q:0,0|2,6|8,30|53,64|67,67|70,70|79,81|84,94|96,112|126,130 S?BSSTT?SEEEETTEEEEETTHHHHHHHHH?????----?---????--???HHHHHHHHHHTT??S??B--------TTB??EEEEEEEETTT-EEEEEEEEEEEEEHHHH--??????-????SSEEE 2IPQ|X PF07516.8_SecA_SW_seed 171 402 !Q:0,8|57,84|86,91|97,97|108,112|118,122|125,132|134,134|137,141|154,162|169,173|175,180|185,228|232,233|247,258|260,262|264,264|270,320|322,323|360,361|365,365|395,397|399,401 Q:9,56|85,85|92,96|98,107|113,117|123,124|133,133|135,136|142,153|163,168|174,174|181,184|229,231|234,246|259,259|263,263|265,269|321,321|324,359|362,364|366,394|398,398 ????-----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?---------------------------S--?--?HHHHH-HHHHHHHHHH-----HHTTS----?TT------??G-GG??---HHHHHHHHHHHS-?-?--???HHHHHH-----H-----?GGGT--------------------------------------------THH--HHHHHHHHHHHHH------------H---H-HHHHH?--------------------------------------------------H--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGGT??SSS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHH---H??? 1M6N|A PF07517.9_SecA_DEAD_seed 90 848 !Q:1,1|6,10|14,17|25,38|41,41|57,57|73,79|83,129|133,162|167,169|181,226|230,233|244,252|256,256|260,261|265,265|283,283|300,300|311,312|314,315|318,319|323,373|375,375|381,443|449,450|462,465|471,471|474,474|480,511|529,529|536,538|553,554|560,561|565,567|569,570|583,583|587,587|591,743|762,763|770,771|774,775|779,779|783,784|786,786|789,791|805,810|818,818|829,829|836,839 Q:0,0|2,5|11,13|18,24|39,40|42,56|58,72|80,82|130,132|163,166|170,180|227,229|234,243|253,255|257,259|262,264|266,282|284,299|301,310|313,313|316,317|320,322|374,374|376,380|444,448|451,461|466,470|472,473|475,479|512,528|530,535|539,552|555,559|562,564|568,568|571,582|584,586|588,590|744,761|764,769|772,773|776,778|780,782|785,785|787,788|792,804|811,817|819,828|830,835|840,847 G-GGGG-----HHH----HHHHHHH--------------HH-HHHHHHHTSHHHHSS?HHHHHHHHHHHHHHH-------HTT--------------------------------------?-------?HHH------------------------------HHHH---HHHHHHHHHHH----------------------------------------------HHS????HHHHHHHHHH---------HHT?EEE??TTS?HHHHHHHHHHHHHTTTT?EEEEESSHHHHHHHHH-HHHHHHHHTT??E--EE??TTS?--------------------------------------------------H-HHHHH---------------------------------------------------------------HHHSS--EEEEEHHHHHH----HHHHH-TT?SSGGG?---------------------??-?---???EEEEETHHHHHTGGGSS?EEEEEE???THHHHHHHHHHHTT??SSSSB??SSS???B??SSHHHHTTGGGT?TTT?TTT---------------------------------------------------------------------------------------------------------------------------------------------------------HHHHHHHHHHHHHHHHHT??HHHHEE??TT??EEB?TTT??B?TT???GGGHHHHHHHHTT??????EEEEEEE?HHHHHTTSSE-EEEEES?--?GGGHHHHH 1M6N|A PF07521.7_RMMBL_seed 138 48 !Q:4,5|11,12|15,15|18,19|30,30|33,36|45,45 Q:0,3|6,10|13,14|16,17|20,29|31,32|37,44|46,47 EEEE??SEEEE??TT?SS??HHHHHHHHHH?BS?--?SEEEEESS?HH 3AF6|A PF07522.9_DRMBL_seed 43 171 !Q:9,9|13,13|19,19|23,28|30,30|32,35|49,57|65,84|86,127|138,140|143,144|156,157|159,160|165,165|168,168 Q:0,8|10,12|14,18|20,22|29,29|31,31|36,48|58,64|85,85|128,137|141,142|145,155|158,158|161,164|166,167|169,170 TTHHHHEES?GGG?SEEEE-EGG------G?S----HHHHHHHHHSGGG?------??EEEEEEE??--????????????-???E------------------------------------------EETTEEEEEE???SS??HHHHHHHHHHH??S--EEEE?SS?SS 4B87|A PF07523.7_Big_3_seed 40 89 !Q:0,2|4,5|12,17|19,19|29,29|35,38|40,41|49,58|62,62|74,79 Q:3,3|6,11|18,18|20,28|30,34|39,39|42,48|59,61|63,73|80,88 ???S??EEETTT?????-S?EEEEEETTS?EEEEE----S??TTSEEES--------??TTS?SSEEEEEEETT------EEEEEEEEE 2KPN|A PF07525.11_SOCS_box_seed 141 47 !Q:0,2|15,16|18,28|35,35|45,47 Q:3,14|17,17|29,34|36,44 ???HHHHHHHHHHHH-?S?----------GGGSSS?HHHHHHHHT??- 2IZV|A PF07527.8_Hairy_orange_seed 79 55 !Q:18,18|23,33|36,37|54,54 Q:0,17|19,22|34,35|38,53 THHHHHHHHHHHHHHHHH-HHTS??--------?TT-?HHHHHHHHHHHHHHHH? 2DB7|A PF07528.9_DZF_seed 4 258 !Q:1,1|8,10|13,14|25,26|46,50|65,65|70,71|79,79|89,100|102,102|104,105|131,135|151,151|172,173|178,180|202,204|206,206|209,209|212,213|219,220|242,244|251,257 Q:0,0|2,7|11,12|15,24|27,45|51,64|66,69|72,78|80,88|101,101|103,103|106,130|136,150|152,171|174,177|181,201|205,205|207,208|210,211|214,218|221,241|245,250 E?HHHHHT???TT??EEEEEEEESS??BHHHHHHHHHHHHHHGGGT?????EEEEETTTTEEEEE?SSSS??EEEEEEE?HHHHHHHHH????????????S?B??HHHHHHHHHHHHHHHHHHHHTTTST-----THHHHHHHHHHHHHH?GGGGGGTTHHHHHHHHHHHH--SSSS???HHHHHHHHHHHHHTTTTSTTS???B?TT?SS??BTTTT??HHHHHHHHHHHHHHHHHHHTT--?HHHHTT??????? 4AT8|A PF07531.9_TAFH_seed 14 101 !Q:20,20|24,24|44,44|58,61|79,79|81,81|90,100 Q:0,19|21,23|25,43|45,57|62,78|80,80|82,89 HHHHHHHHHHHHHHHHHHTS-SSS?HHHHHHHHHHHHHHHTTSS?HHHHHHHHHHHTT????TTHHHHHHHHHHHHHHT?S?HHHHHHHT?????--???? 2P6V|A PF07533.11_BRK_seed 20 51 !Q:0,2|5,5|7,8|19,19|24,24|36,36|43,49 Q:3,4|6,6|9,18|20,23|25,35|37,42|50,50 ???TT?B??EEETTTTEEE?TTSS?BHHHHHHHHHH?TTEEES???????T 2DL6|A PF07534.11_TLD_seed 112 270 !Q:2,2|7,7|10,10|12,12|16,17|24,30|32,33|35,35|41,53|56,56|60,67|76,86|89,94|96,100|103,104|109,119|123,123|128,134|137,149|155,160|163,170|174,174|176,176|180,195|197,197|204,204|207,207|209,209|213,217|219,231|236,237|239,241|244,253|268,269 Q:0,1|3,6|8,9|11,11|13,15|18,23|31,31|34,34|36,40|54,55|57,59|68,75|87,88|95,95|101,102|105,108|120,122|124,127|135,136|150,154|161,162|171,173|175,175|177,179|196,196|198,203|205,206|208,208|210,212|218,218|232,235|238,238|242,243|254,267 EE-EEHH-HH?S?HHH--HHHHHT-------T??S?EEEEE-------------EE-TTS--?-----EEEEEESS??------???SS-----?B??---TT?-EEEE?----------SSS?EEEE?-----?SS?---------???EEEET------TE--------EEE-S?SSS----------------S?SEEEET-TS?E-EEE--?-?B-------------TTTT--B?-?SS----------SSSEEEEEEEEEEE?? 4ACJ|A PF07535.7_zf-DBF_seed 29 66 !Q:0,5|14,14|16,16|20,36|48,48|64,65 Q:6,13|15,15|17,19|37,47|49,63 ??????EETTTTEE?S?HHH-----------------HTTSHHHHHHH-HSSTTHHHHHHHTTS?? 4F9A|B PF07537.6_CamS_seed 7 351 !Q:1,4|14,16|18,18|38,38|42,42|47,48|51,51|62,74|77,83|86,87|89,96|101,108|138,138|144,144|149,151|153,155|159,160|184,187|189,189|193,193|201,203|206,206|209,210|214,215|225,228|231,232|240,241|248,248|266,268|270,275|295,297|299,299|319,319|323,323|342,342|345,345|348,348 Q:0,0|5,13|17,17|19,37|39,41|43,46|49,50|52,61|75,76|84,85|88,88|97,100|109,137|139,143|145,148|152,152|156,158|161,183|188,188|190,192|194,200|204,205|207,208|211,213|216,224|229,230|233,239|242,247|249,265|269,269|276,294|298,298|300,318|320,322|324,341|343,344|346,347|349,350 S????TTTTHHHHH?--S?HHHHHHHHHHHHHHHTTTS?TTT?EEEE??SS?HHHHHHHHSB??-----------SS?------TT??B??---???SSTT??---???EEEEEEEEEEEEEETTEEEEEEEEEEEEE?SEEEE?SSTT???E---EEE??HHHHHHHHHHHHHHHHHHHTTST----T?SSS?EEEEEEE???TT?SS??EEE--EEEEESSSS????EE??EEEEEES?-HHHHHH?HHHHHHHHHHHHHHHHH??-S--????EEEEEEETTEEEEEEEEEE???S?HHHHHHHHHHHHHHHHHHS?TTS-EEEEEEEETTEEEEEEEE?TT?SS?EE 3N2Q|A PF07541.7_EIF_2_alpha_seed 78 171 !Q:1,1|16,16|24,24|32,32|35,36|41,76|93,96|101,103|106,107|117,117|121,122|127,128|132,135|140,148|160,161|167,167 Q:0,0|2,15|17,23|25,31|33,34|37,40|77,92|97,100|104,105|108,116|118,120|123,126|129,131|136,139|149,159|162,166|168,170 H-HHHHTHHHHHHHTT?SSHHHHH-HHHHTTT?GG--GGGG??--??------------------------------HHHHHHHHHHHHHHTS????EEEE???EE??STTTHHHHH-HHH--HHHH--HSS----BTTB?--------EEEEEEETTEE--EEEEE?SSH 3QSY|B PF07542.6_ATP12_seed 100 182 !Q:1,3|5,5|10,10|12,20|25,25|35,35|37,37|39,39|42,42|44,45|48,48|51,52|62,64|67,70|73,74|78,78|94,96|98,112|127,127|133,147|150,158|177,179 Q:0,0|4,4|6,9|11,11|21,24|26,34|36,36|38,38|40,41|43,43|46,47|49,50|53,61|65,66|71,72|75,77|79,93|97,97|113,126|128,132|148,149|159,176|180,181 B???S?EEEE-E---------ETTE-EEEEETTEE?B?T-TS?B??BS?HH--HHHHHHHHH---HT?--?SB??GGG?HHHHHHHHHHHTTGG---G---------------HHHHHHHHHHGGGS?GGGEE???-----------?HH---------HHHHHHHHHHHHHHHHHH---HS 2R31|A PF07545.9_Vg_Tdu_seed 3 33 !Q:0,1|11,11|15,15|29,32 Q:2,10|12,14|16,28 ??EETTEEEEE?SSS?HHHHHHHHHHTTS???? 4EAZ|C PF07549.9_Sec_GG_seed 145 31 !Q:8,11|16,16|25,25|28,29 Q:0,7|12,15|17,24|26,27|30,30 HHHHHHHT????HHHH?EEEEEEEE?TT??H 3AQP|A PF07553.6_Lipoprotein_Ltp_seed 18 55 !Q:0,0|3,3|18,20|32,39|41,43|54,54 Q:1,2|4,17|21,31|40,40|44,53 ?HH-HHHHHHHHHHHHHH???HHHHHHHHHHT--------T???HHHHHHHHHT? 4EQQ|A PF07554.8_FIVAR_seed 225 63 !Q:1,4|17,21|25,25|44,55 Q:0,0|5,16|22,24|26,43|56,62 H----TTHHHHHTSHHH-----HTS?HHHHHHHHHHHHHHHHHT??-??-???-??HHHHHHH 2OZN|B PF07555.8_NAGidase_seed 30 370 !Q:5,6|10,12|28,32|37,38|41,41|52,54|59,59|74,74|81,82|86,92|95,98|117,118|124,125|127,128|131,147|150,150|171,179|184,184|187,187|193,193|195,198|201,201|211,211|219,220|225,230|238,244|251,251|257,258|260,261|264,265|269,272|274,278|280,280|283,284|287,288|296,298|300,300|311,314|321,321|325,328|341,341|343,356 Q:0,4|7,9|13,27|33,36|39,40|42,51|55,58|60,73|75,80|83,85|93,94|99,116|119,123|126,126|129,130|148,149|151,170|180,183|185,186|188,192|194,194|199,200|202,210|212,218|221,224|231,237|245,250|252,256|259,259|262,263|266,268|273,273|279,279|281,282|285,286|289,295|299,299|301,310|315,320|322,324|329,340|342,342|357,369 EEEEE??SSS???HHHHHHHHHHHHHTT??---EEEE??TT?TTTSTTTTTS???HHHH-HHHHHHHHHHHHTT?EEEEEE??TTT??-----SS----HHHHHHHHHHHHHHHHTT??EEEEE??S??SG-----------------GG?HHHHHHHHHHHHHHTTTTSS????-----EEEE?SS?SGGGS?T----TS?HHHHHHHHS?TTSEEEE??SSSS--????HHHHHHH-------HHHHTS?EEEEE??S??TT--STT????S????-S?SS?-GG--GEEEEEE???S?HHHHHHHHHH----HHHHHH?GGG?--?HHHHHHHHHHHH?G--------------GGHHHHHHHHHTS 2J47|A PF07559.9_FlaE_seed 180 442 !Q:0,1|3,5|7,7|11,11|14,14|19,19|23,23|26,27|29,37|46,46|48,82|86,90|102,187|190,224|226,229|231,232|239,240|242,248|251,253|255,258|260,333|336,337|343,345|350,366|372,381|383,411|413,413|419,425|427,428|434,436|438,440 Q:2,2|6,6|8,10|12,13|15,18|20,22|24,25|28,28|38,45|47,47|83,85|91,101|188,189|225,225|230,230|233,238|241,241|249,250|254,254|259,259|334,335|338,342|346,349|367,371|382,382|412,412|414,418|426,426|429,433|437,437|441,441 ??T---T?TTS?SE-EEEE-EEE?TT??E---------EEEEEEEE-E-----------------------------------EET-----TEEEEEEEETT?-------------------------------------------------------------------------------------TT-----------------------------------S????S?-SEEEEE?-T-------TS---B----E--------------------------------------------------------------------------EE??EEEEE???BTTB???--------------EEEEE?---------T-----------------------------T?EEESS---??-?E--EEEEE---E-??B 2BGZ|A PF07562.9_NCD3G_seed 119 61 !Q:0,3|6,9|15,17|20,21|25,25|27,28|33,34|41,43|47,47|52,53|56,57 Q:4,5|10,14|18,19|22,24|26,26|29,32|35,40|44,46|48,51|54,55|58,60 ????SS????TTTEE---EE??SSS-S??EEEE??TTEEEE---ETT-EEEE??TT--EEE 2E4W|A PF07563.6_DUF1541_seed 25 53 !Q:0,0|3,3|10,10|15,15|18,18 Q:1,2|4,9|11,14|16,17|19,52 ?TT?EEEBSS?SSTT?TT?EEEEEEEEEEEEEEEEEEETTTTEEEEEEEEEET 2KY9|A PF07565.8_Band_3_cyto_seed 32 395 !Q:3,3|7,7|9,11|13,15|17,17|31,31|38,40|60,60|74,74|77,84|88,94|100,100|104,104|107,107|111,150|153,154|157,161|168,170|173,173|175,257|259,259|271,271|274,275|282,290|296,296|299,299|311,316|320,320|323,325|335,338|341,342|366,366|383,383|387,390|392,392|395,395 Q:0,2|4,6|8,8|12,12|16,16|18,30|32,37|41,59|61,73|75,76|85,87|95,99|101,103|105,106|108,110|151,152|155,156|162,167|171,172|174,174|258,258|260,270|272,273|276,281|291,295|297,298|300,310|317,319|321,322|326,334|339,340|343,365|367,382|384,386|391,391|393,394 EEB?TTS?B???B???B?HHHHHHHHHHHHT?EEEEEE???SHHHHHHHHHHHHHHTTSS?GGGHHHHHHHHTS?EE-------?HHH-------HHHHT?EEE?EE?TTS---------------------------------------?EE??SS?????HHHHHH???SS?S-----------------------------------------------------------------------------------S?TTGGGGGGGGS?TT??EEEEEE---------EEBTT?SS?EEEEEEEEEEE?----?TTS-SS???EEEEEEEEE?-??TT??HHHHHHHHHHHHTSHHHHHHHHH?SSHHHHHHHHHHHHHT?EEE????S?HH- 1HYN|P PF07566.7_DUF1543_seed 44 66 !Q:0,0|3,3|26,31|33,33|37,37|45,46|49,52|59,64 Q:1,2|4,25|32,32|34,36|38,44|47,48|53,58|65,65 ?SS?EEEEEEEEESSSGGGHHHHHHH?----?S?STT?EEEEEEE??EE----TTEEEE------E 2QSD|A PF07571.8_DUF1546_seed 29 129 !Q:6,6|9,41|44,45|71,72|84,84|86,93|96,97|112,113 Q:0,5|7,8|42,43|46,70|73,83|85,85|94,95|98,111|114,128 HHHHHH?TT?------------------------------??HH--HHHHHHHHHHHHHHHHTTTSTTHHH--HHHHHHHHHHT?T--------TS-?HHHHHHHHHHHHHH-?HHHHHTHHHHHHHHH 4ATG|A PF07574.8_SMC_Nse1_seed 9 261 !Q:12,12|32,51|75,102|106,107|118,118|128,128|149,149|153,159|169,169|173,175|177,226|243,243|253,253 Q:0,11|13,31|52,74|103,105|108,117|119,127|129,148|150,152|160,168|170,172|176,176|227,242|244,252|254,260 HHHHHHHHHHHH-SSEEEHHHHHHHHHHHHHH??--?-----?----?????HHHHHHHHHHHHGGGTEEEEEEE?---------------------------TTT??EEEEEEESSS?TTHHHHTTS?HHHHHHHHHHHHHHHHSSSS?EEH-------HHHHGGGTT?SSS???H--------------------------------------------------HHHHHHHHHHHHTTSE-EEETTEEEE?HHHHHHH 3NW0|A PF07575.8_Nucleopor_Nup85_seed 20 705 !Q:0,1|3,3|5,8|11,15|38,56|82,82|89,89|98,103|117,120|122,122|125,125|127,127|147,149|151,151|157,165|170,171|178,178|197,197|206,207|220,220|237,256|259,259|281,283|285,285|302,302|309,312|314,314|329,338|354,370|386,387|398,400|412,415|420,444|451,451|468,469|483,483|487,487|502,505|522,522|552,704 Q:2,2|4,4|9,10|16,37|57,81|83,88|90,97|104,116|121,121|123,124|126,126|128,146|150,150|152,156|166,169|172,177|179,196|198,205|208,219|221,236|257,258|260,280|284,284|286,301|303,308|313,313|315,328|339,353|371,385|388,397|401,411|416,419|445,450|452,467|470,482|484,486|488,501|506,521|523,551 ??B?B????SS?-???TTHHHHHHHHHHHHHHSTTTTS??????????????-----SHHHHHHHHHHHHHHHHHHHHHHHH-HHHHSS?HHHHHHHH------HHHHHHHHHHHHS----S?SS-S?TTTTHHHHHHHHHHHHHSS???S?HHHHG---------GGGS??HHHHSS?GGGSHHHHHHHHHHHHTT?HHHHHHHH--TTTTTTTGGGGT?HHHHHHHHHHHHHHTT??------------------SS?HHHHHHHHHHHHHHHHHHHTS???S?HHHHHHHHHHHHHHTT?HHHHHH----T?SSHHHHHHHHHHHT??----?---TTTHHHHHHHHHTTS--------------???SSSTTHHHHHHHHHS??TTTHHHHHTT--?HHHHHHHHHHH----HHTT?????????????????????????SSSSSS?HHHHHHHHHHHHHHTT??TTTHHHHHHHHHS?SSS?HHHHHHHHHHHGGG????SHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHH?????????--------------------------------------------------------?--------------------------------------------------------------------------------------- 3F3G|C PF07582.7_AP_endonuc_2_N_seed 56 57 !Q:0,0|13,14|16,16|20,23|27,27|43,56 Q:1,12|15,15|17,19|24,26|28,42 ?HHHHHHHHHHTT??S?EEE????TTS?HHHHHHHHHHHHHTT--???????????? 3LMZ|A PF07591.6_PT-HINT_seed 4 140 !Q:3,3|13,14|17,17|23,23|27,28|53,57|63,63|66,66|81,82|85,85|93,93|119,120|126,130|138,139 Q:0,2|4,12|15,16|18,22|24,26|29,52|58,62|64,65|67,80|83,84|86,92|94,118|121,125|131,137 EEE?SSSEEEGGG??TT?EEEEE?TTT??EEEEEEEEEEEEEEEEEEEEEETT-----EEEEE?TT?EEEETTTEEEEGGG??TT?EEEBTTS?EEEEEEEEEEEEEEEEEEEEEEESS??EEEET-----TTTEEEE?- 2LWY|A PF07615.6_Ykof_seed 13 83 !Q:0,0|10,11|27,30|38,38|41,41|47,47|66,66|68,68|78,79|82,82 Q:1,9|12,26|31,37|39,40|42,46|48,65|67,67|69,77|80,81 ?EEEEEEEEE?-STTHHHHHHHHHHHS?--?TTSEEEE?SS?EEEEE?HHHHHHHHHHHHHHHHTT?S?EEEEEEEEE??TT? 1S99|A PF07632.6_DUF1593_seed 29 414 !Q:6,8|12,13|38,39|41,44|48,83|89,89|91,93|111,127|138,139|142,159|164,164|168,171|184,184|186,186|188,189|191,191|199,199|215,215|219,223|238,239|241,249|252,252|260,260|263,263|270,272|276,306|310,311|319,319|328,370|375,383|394,394|398,399|406,407|409,409|411,413 Q:0,5|9,11|14,37|40,40|45,47|84,88|90,90|94,110|128,137|140,141|160,163|165,167|172,183|185,185|187,187|190,190|192,198|200,214|216,218|224,237|240,240|250,251|253,259|261,262|264,269|273,275|307,309|312,318|320,327|371,374|384,393|395,397|400,405|408,408|410,410 EEEEEE?--TTS-?THHHHHHHHHHHTGGGSEEEEEEE??B----TTB???------------------------------???HHHHH-H---HHHHHHHHHHHTTTSTT--------------???HHHHHHTEEE??SS-----------------?GGGG?STT??-?HHHHHHHHHHHS-S?S--S?EEEEESS?SHHHHHHHHHHHHHS?HHH-----HHHHHHTEEEEEES??S---------HH-HHHHHHH?TT-SEEEEE???SSS??----------------------------?HHH--HHHHTTT-SHHHHHTS??----------------------------------------?SSSS--------?TTTHHHHTTS?TTT??TTSTTS??T-T??? 2YHG|A PF07638.6_Sigma70_ECF_seed 7 212 !Q:14,14|38,43|53,55|68,69|73,73|94,95|98,107|109,111|116,122|126,130|133,134|137,147|160,160|162,162|176,178|189,189|202,206 Q:0,13|15,37|44,52|56,67|70,72|74,93|96,97|108,108|112,115|123,125|131,132|135,136|148,159|161,161|163,175|179,188|190,201|207,211 HHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHTTTS-----?GGGHHHHHH---HHHHHHHHHGGG??SSS?HHHHHHHHHHHHHHHHHHTT??TH----------H---HHHH-------HHH-----HS??SS???????????EEEHHHHHHHHH-S?HHHHHHHHHHHTT???HHHHHHHTTS?HHHHHHHHHHHH-----HHHHH 2H27|A PF07645.10_EGF_CA_seed 18 57 !Q:1,2|7,7|9,17|33,42|44,44|47,48|54,55 Q:0,0|3,6|8,8|18,32|43,43|45,46|49,53|56,56 E??HHHH-T?-???---?TTSEEEEETTEEEEE----??????B?TT??SSBTT??B 1HZ8|A PF07646.10_Kelch_2_seed 42 71 !Q:0,1|4,4|8,8|11,17|25,26|28,44|50,52|67,69 Q:2,3|5,7|9,10|18,24|27,27|45,49|53,66|70,70 ??BS?EEE-EE-------TTEEEEE??B-----------------SSSSB???EEEEETTTTEEEEE???S 2VPJ|A PF07647.12_SAM_2_seed 49 79 !Q:0,5|14,16|19,20|22,24|36,37|43,44|47,48|53,55|57,57|61,63 Q:6,13|17,18|21,21|25,35|38,42|45,46|49,52|56,56|58,60|64,78 ??????SSHHHHHH---HT--T?--GGGHHHHHHTT??SHHHH--HT??HHHH---H-HTT???HHHHHHHHHHHHHHH 1B0X|A PF07648.10_Kazal_2_seed 73 70 !Q:2,10|13,18|23,26|31,32|44,61|67,69 Q:0,1|11,12|19,22|27,30|33,43|62,66 EE????--?--EE------ETTS?---EESS--HHHHHHHHHHH-----------???--??EEESS?-? 1SGN|I PF07649.7_C1_3_seed 194 41 !Q:0,2|5,5|8,11|13,17|21,25|27,27|30,36 Q:3,4|6,7|12,12|18,20|26,26|28,29|37,40 ???TT-TS????S----?EEE--?--T-TT-????-?HHHH 1V5N|A PF07650.12_KH_2_seed 165 113 !Q:10,10|12,16|20,26|32,33|35,39|42,42|44,47|53,53|59,59|77,80|83,100|104,105|107,107|109,109 Q:0,9|11,11|17,19|27,31|34,34|40,41|43,43|48,52|54,58|60,76|81,82|101,103|106,106|108,108|110,112 HHHHHHHHTT-T-----TTT-------EEEEE??B-----SS-S????EEEES?HHHHH?SSSHHHHHHHHHTTTTT----TS?--------------???EEE--E?S?TTS 3KIX|c PF07651.11_ANTH_seed 29 332 !Q:0,1|12,12|17,19|32,32|34,36|39,39|53,53|55,55|75,75|87,91|94,105|108,110|141,152|156,183|186,193|195,196|218,220|224,227|259,262|267,270|303,304|308,309|311,317|331,331 Q:2,11|13,16|20,31|33,33|37,38|40,52|54,54|56,74|76,86|92,93|106,107|111,140|153,155|184,185|194,194|197,217|221,223|228,258|263,266|271,302|305,307|310,310|318,330 ??HHHHHHHHHS?SSSS???HHHHHHHHHHHH?T---TS?HHHHHHHHHHHHT?S-SHHHHHHHHHHHHHHHHHS?HHHHHHHHHTT?????TT??????-?????SS???TTHHHHHHHHHHHHHHHHHHHHHHHHHHSS?-----------GGG????--------------?-----????TT--------T??HHHHHHHHHHHHHHHHHHHTT???GGG??--SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH----HHTT--??SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??GGG--S???????HHHHHHHHHHHHT? 1HX8|A PF07652.9_Flavi_DEAD_seed 19 149 !Q:4,4|9,11|33,34|56,57|59,72|89,89|92,96|106,107|127,127|133,133|136,136|139,141|144,146 Q:0,3|5,8|12,32|35,55|58,58|73,88|90,91|97,105|108,126|128,132|134,135|137,138|142,143|147,148 SSTT?EEEE???TTSSTTTTHHHHHHHHHHHHT??EEEEESSHHHHHHHHHHTTTS??B??????????????SEEEEEHHHHHHHHTS-SS?????SEEEEESTT??SHHHHHHHHHHHHHHHHTS?EEEEE?SS?TT???SS???SS 2V6I|A PF07653.12_SH3_2_seed 35 131 !Q:4,4|6,6|8,11|13,13|18,36|38,38|41,44|50,75|77,80|83,91|94,94|98,98|101,102|104,110|114,119|130,130 Q:0,3|5,5|7,7|12,12|14,17|37,37|39,40|45,49|76,76|81,82|92,93|95,97|99,100|103,103|111,113|120,129 EEEE?S?B??--S-STTB-----------------??B?TT?---EEEEE--------------------------E?--?SS---------SE-EEE-EE--T-------TEE------EEEESSSEEE? 1MUZ|A PF07654.10_C1-set_seed 128 104 !Q:1,15|27,28|30,31|36,36|44,44|50,52|55,60|64,64|73,77|79,80|83,86|93,93|96,96|98,99|101,101 Q:0,0|16,26|29,29|32,35|37,43|45,49|53,54|61,63|65,72|78,78|81,82|87,92|94,95|97,97|100,100|102,103 E?-???-??---????EEEEEEEEEBS--S??EEEE-EETTEEE?TTEEE???EE-?----SSS?EEEEEEEE??---S-?TT?--?EEEEEE?TT?S--S?EE 1DN2|A PF07660.9_STN_seed 154 70 !Q:0,0|4,6|8,9|15,18|20,28|31,31|33,39|52,53|58,58|64,64|68,69 Q:1,3|7,7|10,14|19,19|29,30|32,32|40,51|54,57|59,63|65,67 ?EEE??-T--TTTTT---?B????---?-SE-E------?HHHHHHHHHTTS??EEEE-ETTEE-EEE?? 2W76|A PF07662.8_Nucleos_tra2_C_seed 161 314 !Q:21,28|30,77|117,117|121,123|125,131|135,146|148,148|150,159|161,174|192,195|197,197|214,214|224,225|232,232|235,247|259,259|261,262|278,279|289,289|313,313 Q:0,20|29,29|78,116|118,120|124,124|132,134|147,147|149,149|160,160|175,191|196,196|198,213|215,223|226,231|233,234|248,258|260,260|263,277|280,288|290,312 HHHHHHHHHHHHHHHHHHHHS??-----?S?-??-??--------????-??----------????----------??SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHH---H-------GGG------------T?T----------T?------------?HHHHHHHHHHHHHHHTT?-?-G-GGHHHHHHHHHHHHHT?HHHHHHHHG--GGGSTT?SS?----------??HHHHHHHHHHT?S??STHHHHHHHHHTGGG?-GGGHHHHHH-HHHHHHHHHHHHHHHHHHHHHHH? 3TIJ|A PF07669.6_Eco57I_seed 29 129 !Q:0,4|11,16|19,21|25,25|28,30|41,42|45,46|60,60|72,72|77,78|80,80|101,104|108,108|112,115|125,126|128,128 Q:5,10|17,18|22,24|26,27|31,40|43,44|47,59|61,71|73,76|79,79|81,100|105,107|109,111|116,124|127,127 -----EEEEEE??????BS--?TTT?SB???HHHHHHHHTT??TT??HHHHHHHHHHHHE-EEEEEEEEEEE-GGGG--T?GGGHHHHHHHHHHSEEEEEE----EES?STT????EEEEEEESS--S? 2JG3|A PF07670.9_Gate_seed 238 259 !Q:21,68|82,82|88,93|100,100|105,108|112,112|124,200|203,204|206,207|212,212|218,220|225,238|243,243|245,246|250,252|256,257 Q:0,20|69,81|83,87|94,99|101,104|109,111|113,123|201,202|205,205|208,211|213,217|221,224|239,242|244,244|247,249|253,255|258,258 HHHTHHHHHHHHHHHHHHHHT------------------------------------------------THHHHHHHHHHHH-HHHHH??---?HHHHHH-HHHT----TTS?TTTGGGGGGGG-----------------------------------------------------------------------------ST--T??HHHH-HHHHH---HHHH-??----------?HHHH-H--HHH---HTT??H 3TIJ|A PF07675.6_Cleaved_Adhesin_seed 9 194 !Q:0,0|6,7|11,11|13,13|23,23|26,27|32,32|38,44|50,51|58,58|65,70|76,83|86,86|98,98|102,104|114,115|120,121|123,123|129,135|137,143|146,148|150,154|162,162|165,169|178,179|182,184 Q:1,5|8,10|12,12|14,22|24,25|28,31|33,37|45,49|52,57|59,64|71,75|84,85|87,97|99,101|105,113|116,119|122,122|124,128|136,136|144,145|149,149|155,161|163,164|170,177|180,181|185,193 ?EEEEE??TTS-S?TTSEEEESS?SS??SBSS?TTTTS----???BTTBS??EEEESE-ETTTEE---???EEEEE?????--?TT?EEEEEEEEESS-TTS???EEEEEEESS??SGGG??S?SEEEE----???S???????SS???S?????EEEEEEE?TT??---EEEEEEES??SS?--EEEEEEEEE 3KM5|A PF07676.7_PD40_seed 127 59 !Q:3,5|9,20|27,27|38,38|41,46|49,49|51,55 Q:0,2|6,8|21,26|28,37|39,40|47,48|50,50|56,58 EEE???SSS-----------?EEEEEE?TTSSEEEEEE?TT------SS?E-----EEE 1K32|A PF07677.9_A2M_recep_seed 92 106 !Q:1,1|9,10|16,16|31,36|43,43|47,47|56,56|58,58|62,62|72,73|75,76|79,82|92,92|94,97|100,100 Q:0,0|2,8|11,15|17,30|37,42|44,46|48,55|57,57|59,61|63,71|74,74|77,78|83,91|93,93|98,99|101,105 B?SEEEEEE??TTEEE?HHHHHHHHHSSSEE----??HHHHHS?GGG?SEEEEEES?B?SSS?EEEEEEEEE-?S??SS?-??EEEEEEESS?S----SS?EEEEE 4FXG|C PF07678.9_A2M_comp_seed 43 389 !Q:4,5|12,13|17,19|21,21|24,27|33,39|52,63|69,70|72,74|89,89|94,94|98,103|105,105|109,112|114,123|125,125|142,154|157,187|198,198|209,209|229,230|245,246|248,276|279,282|284,290|293,294|296,296|302,316|332,332|335,336|339,346|363,365|369,370 Q:0,3|6,11|14,16|20,20|22,23|28,32|40,51|64,68|71,71|75,88|90,93|95,97|104,104|106,108|113,113|124,124|126,141|155,156|188,197|199,208|210,228|231,244|247,247|277,278|283,283|291,292|295,295|297,301|317,331|333,334|337,338|347,362|366,368|371,388 HHHH--HHGGGB-?TTS--?B?SS----TTGGG--?????HHHHHHHHHHHH------------HHTTT--S???THHHHHHHHHHHHT-EETT-TEE??????S?GGG??--S?---------S?HHHHHHHHHHHHHHTT-----------??TT------------------------------?HHHHHHHHHH-HHHHHHHTSS?SSSTHHHHHHHHHHHHHHT-?HHHHHHHHHHHHHH??B?----------------------------SS?---B???????SS--S?SSSTT?------------??TTGGGGTHHHHHHHH-HH??SS?-----??HHHHHHHHTTHHHHTT???TTS??SSHHHHHHHHHHHHHHHH 4FXG|B PF07679.11_I-set_seed 48 113 !Q:5,9|17,17|28,28|30,31|39,40|44,58|67,67|69,73|75,75|84,85|89,89|100,100 Q:0,4|10,16|18,27|29,29|32,38|41,43|59,66|68,68|74,74|76,83|86,88|90,99|101,112 EEEEE??-??EEEETTS?EEEEEEEEEE-S??EEEEEET--TEE???------------SSSEEEEE?T-----T?EEEEEESS??GGG?EEEEEEEEET-TEEEEEEEEEEE 3ETB|F PF07682.6_SOR_seed 3 328 !Q:0,2|13,13|50,51|59,60|62,63|67,67|69,81|125,125|135,140|156,158|162,168|182,182|185,185|203,203|219,219|225,227|237,238|242,244|248,252|254,254|259,264|267,267|291,291|300,300|309,309 Q:3,12|14,49|52,58|61,61|64,66|68,68|82,124|126,134|141,155|159,161|169,181|183,184|186,202|204,218|220,224|228,236|239,241|245,247|253,253|255,258|265,266|268,290|292,299|301,308|310,327 ???EEEEEEEEEE?SHHHHHHHHHHHHHHHHHHTTSTTEEEEEEEEEEEE??TTTTTTT??S??TTT?S-------------EEEEEEEEEESSHHHHHHHHHHTHHHHHHHHHTTGGGEEEEEE?EEEEEEEEE??????TTTHHHHHHHHHHTT?--GGG???????SSSSEEEEEEEEE?TT?HHHHHHHHHHHHHHGGG-STTEEEEEEEEEEEE?TTTTT???HHHHHHHHH??SSS???GGG??---S?GGGG?----?SS?EEEEEEEESSHHHHHHHHTHHHH?HHHHHHHH-HHHTSEEE-EEEEEEEEEEEEETTHHH 2YAX|A PF07683.9_CobW_C_seed 158 155 !Q:10,10|12,12|14,17|28,30|36,43|46,47|56,56|59,62|64,65|68,68|83,83|88,88|91,119|121,123|130,132|135,136|138,142|154,154 Q:0,9|11,11|13,13|18,27|31,35|44,45|48,55|57,58|63,63|66,67|69,82|84,87|89,90|120,120|124,129|133,134|137,137|143,153 EEEEEEEESS?B?H----HHHHHHHHHH---HHHTT--------TT--EEEEEEEE?BT----T?-SE-EEEEEEETTEEEEE-EEEE?TT-----------------------------S???EEEEEE---EE--S??---HHHHHHHHHTT? 4IXN|A PF07684.7_NODP_seed 28 68 !Q:1,1|12,12|16,17|21,21|23,26|43,43|45,47|49,49|52,52|60,67 Q:0,0|2,11|13,15|18,20|22,22|27,42|44,44|48,48|50,51|53,59 S?EEEEEEEEEE?TTH--HHH?S??-?SBHHHHHHHHHHHHHH-T???S-SS?EEEEEEE???????? 3ETO|A PF07685.9_GATase_3_seed 88 198 !Q:6,6|8,8|14,17|28,29|32,32|44,46|63,69|72,87|94,94|99,103|113,118|124,131|137,139|141,142|146,160|163,163|166,166|168,182|188,193 Q:0,5|7,7|9,13|18,27|30,31|33,43|47,62|70,71|88,93|95,98|104,112|119,123|132,136|140,140|143,145|161,162|164,165|167,167|183,187|194,197 SGGGGT-T?SEEEE????HHHHHHHHHH--TT?HHHHHHHHHTT??-EEEETTHHHHHEEEEE-------SS---????------???EEEEEE?HHHH?????EEEEEEETT------TEEEE--------EEEES---S??EEE---------------EE?TT?E---------------EEEEE------TTEE 1OX4|A PF07686.12_V-set_seed 113 197 !Q:0,1|5,8|10,40|45,45|48,49|53,54|60,60|65,72|79,80|82,82|84,91|94,94|102,108|112,113|117,117|132,143|152,152|154,156|160,160|169,169|172,180|183,183|189,191|197,197 Q:2,4|9,9|41,44|46,47|50,52|55,59|61,64|73,78|81,81|83,83|92,93|95,101|109,111|114,116|118,131|144,151|153,153|157,159|161,168|170,171|181,182|184,188|192,196 ??EEE?--?S-------------------------------EEEE?TT??EEE??EEESS?GGGS--------EEEEEE--E?S--------SS?EEEEEEE------?TTT??EEE?GGGTTTEEEEEEGG------------GTEEEEEE?S-??GGG?SEEEEEEE?SS---------SS?SEEEE???EEEEE- 1MCI|A PF07687.9_M20_dimer_seed 178 195 !Q:0,1|3,3|13,20|22,22|26,26|31,31|37,40|44,50|61,61|65,65|67,68|76,79|91,96|98,98|108,109|111,112|115,115|128,128|139,140|144,150|153,153|164,166|168,168|171,174|191,191|195,195 Q:2,2|4,12|21,21|23,25|27,30|32,36|41,43|51,60|62,64|66,66|69,75|80,90|97,97|99,107|110,110|113,114|116,127|129,138|141,143|151,152|154,163|167,167|169,170|175,190|192,194 ??B?EEEEEEEEE--------E?SSS?EEGG-GTTTB??--HHH-------HHHHHHHHTB?TTS?B??TTTGGGS????HHHHHHHHHHS?-----S?GGGHHHHHT??S??SS?SHHHHHHHHHHS?EEEEEEEEEE??SSS???----EE?SEEEEEEEEE---E?TT??--HHHHHHHHHHHHHHTT?TTE- 2RB7|A PF07688.7_KaiA_seed 3 286 !Q:6,8|20,20|30,30|46,46|70,73|79,91|94,94|100,100|104,104|107,107|126,126|128,129|134,135|137,148|174,176|185,185|212,213|230,231|255,256|283,285 Q:0,5|9,19|21,29|31,45|47,69|74,78|92,93|95,99|101,103|105,106|108,125|127,127|130,133|136,136|149,173|177,184|186,211|214,229|232,254|257,282 EEEEEE???HHHHHHHHHHT?STTEEEEEE?SHHHHHHHHHHSTTS?SEEEEETTSTTHHHHHHHHHHTT????EEEES????--???????SS?SSBTT?EEE?TT?GGGHHHHHHHHHHHHHHH?S??BTTT??S-----???????TTGGGHHHHHHHHHHHHHEEEEEEE???GGGSTTTS?HHHHHHHHHHHHHHHHHHHHHHTSTT??HHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHHHHHTTT??TTGGGGGHHHHHHHHHHHHHHHHHHS??? 1R8J|A PF07689.7_KaiB_seed 16 82 !Q:6,7|40,40|42,43|46,47|50,50|59,59|74,75 Q:0,5|8,39|41,41|44,45|48,49|51,58|60,73|76,81 EEEESS??HHHHHHHHHHHHHHHHHHTTSEEEEEEETTTS?S??TT??EE?HHHHGGGS?HHHHHHHHHHHHTS??EEEEEE 1RQM|A PF07690.11_MFS_1_seed 195 793 !Q:14,26|32,38|40,41|44,57|61,102|105,144|150,154|158,161|166,168|172,173|176,178|186,186|190,191|194,197|199,199|201,208|212,212|225,225|231,241|243,245|248,253|258,263|270,272|279,279|297,297|299,303|305,306|310,311|317,319|326,326|330,330|336,339|343,344|348,359|364,367|379,381|383,389|392,424|429,482|486,495|504,510|513,532|543,547|554,557|562,562|564,570|572,579|590,607|626,630|637,637|640,646|650,657|680,698|705,715|727,727|733,736|749,752|754,763|768,772|780,780|785,785|790,791 Q:0,13|27,31|39,39|42,43|58,60|103,104|145,149|155,157|162,165|169,171|174,175|179,185|187,189|192,193|198,198|200,200|209,211|213,224|226,230|242,242|246,247|254,257|264,269|273,278|280,296|298,298|304,304|307,309|312,316|320,325|327,329|331,335|340,342|345,347|360,363|368,378|382,382|390,391|425,428|483,485|496,503|511,512|533,542|548,553|558,561|563,563|571,571|580,589|608,625|631,636|638,639|647,649|658,679|699,704|716,726|728,732|737,748|753,753|764,767|773,779|781,784|786,789|792,792 HHHHHHHHHHHHHH-------------HHHHH-------H--HH--------------HTT------------------------------------------SS----------------------------------------STTHH-----HHH----HHHH---HHH--HH---HHHHTTH-HHH--HT----T-S-----?--III-IIHHHHHHHHHH-HHHHH-----------H---HH------HHHH------HHHHHH---HHHHHH-HHHHHHHHHHHHHHHHT-S-----S??SHH--HHHHH---HHHHHH-HHH-HHHHH----HSS-?HHH------------HHHH----HHHHHHHHHHH---H?--????SS------------------------------???STTT??-------------------------------------------------???TTT?---------STHHHHHH-------HH--------------------HHHHHHHHHH-----HHHHHH----HHHH?S?------S--------SHHHHHHHHH------------------HHHHHHHTHHHHHHHHHH-----HHHTTT-TH-------HHH--------HHHHHHHHHHHTSSSSSHHHHH-------------------HHHHHH-----------HHHHHHHHHHH-HHHHT----SSTTHHHHHTHH----H----------HHHH-----HHHHHHH-HHHH-HHHH??S 2CFP|A PF07691.7_PA14_seed 34 200 !Q:5,5|13,37|39,40|42,42|46,48|55,56|58,58|71,72|81,82|86,92|100,105|113,113|116,119|124,130|135,137|141,143|145,146|153,153|156,156|167,167|170,170|174,182|187,187|191,191|197,197 Q:0,4|6,12|38,38|41,41|43,45|49,54|57,57|59,70|73,80|83,85|93,99|106,112|114,115|120,123|131,134|138,140|144,144|147,152|154,155|157,166|168,169|171,173|183,186|188,190|192,196|198,199 GEETT-TEETTTE-------------------------E??S?TTS???BSTTTT??B?TTSEEEEEEEEE??SSSEEEEE--EES-----??BSEEEEE------ESBTTTB?TT---?TTSS???????SEEE???TTS???S??EEEEEE?TT?BEEEEEEEEE?SS?EEE--------?EEEE?TTS?EEESB?TT 4AI2|A PF07694.7_5TM-5TMR_LYT_seed 106 238 !Q:0,10|14,19|37,39|42,56|58,73|76,81|95,95|117,119|145,146|171,181|191,203|205,213 Q:11,13|20,36|40,41|57,57|74,75|82,94|96,116|120,144|147,170|182,190|204,204|214,237 ?????????-?HHH------HHHHHHHHHHHHHHTTT???TT---------------S?---------------SS--????GGGHHHHHHHTTS?HHHHHHHHHHHHHHHHHHTTT?--SSHHHHHHHHHHHHHHHHHHHHSSS-?SHHHHHHHHHHHHHHHHHHHHHHH-----------TTTTTHHHH?????????????H---------HHHHHHHHHHHHHHHHHHHHHHHH 3P5N|A PF07696.6_7TMR-DISMED2_seed 114 194 !Q:0,8|18,20|25,31|34,34|38,38|41,43|45,49|55,55|57,57|59,59|61,61|70,76|79,79|81,89|95,95|98,98|101,102|109,113|117,122|134,135|137,137|139,142|144,144|147,148|154,159|163,164|173,174|177,177|182,187 Q:9,17|21,24|32,33|35,37|39,40|44,44|50,54|56,56|58,58|60,60|62,69|77,78|80,80|90,94|96,97|99,100|103,108|114,116|123,133|136,136|138,138|143,143|145,146|149,153|160,162|165,172|175,176|178,181|188,193 ???--?-??EEEEEETTS???HHHH-------HT?GGG?EE?--S-----SSEEE-E?S?S?EEEEEEEE----???SS?E---------EEEEE?TT?SE--EEEEEE-----ETT------EEEEEEEESTT--S?S??-?S?TT??EEEEE?----?SSS?-EEEEEEEE?-SS?EEEE------EEEEEH 3JYB|A PF07700.10_HNOB_seed 16 176 !Q:0,0|30,30|33,33|36,37|42,43|61,61|82,82|90,90|103,103|113,114|117,120|128,128|139,139|144,144|161,162|170,170 Q:1,29|31,32|34,35|38,41|44,60|62,81|83,89|91,102|104,112|115,116|121,127|129,138|140,143|145,160|163,169|171,175 ?BHHHHHHHHHHHHHHHHHHHHHHHHHHTT?SS?SS??TTSB??HHHHHHHHHHHHHHHTS?HHHHHHHHHHHHHHHHHHTT?HHHHHHT?SSHHHHHHHHHH-HHHHHHHHS--TT????EEEEEEE-ETTEEEEEEE?SSSS?HHHHHHHHHHHHHHTT??EEEEEEE?TTTTS 1U4H|A PF07701.9_HNOBA_seed 33 355 !Q:0,8|16,16|23,23|26,26|32,32|40,48|56,56|58,63|77,78|80,80|97,116|120,122|128,250|276,354 Q:9,15|17,22|24,25|27,31|33,39|49,55|57,57|64,76|79,79|81,96|117,119|123,127|251,275 -------??HHHHHTT?SSEEEE?TT?BEEEE?HHHHHHH---------GGGHHHH?S------BHHHHEEEEESTT??S?HHHHHHTTTSEEEEEE-----?-------------?SSS--?TTTTT--------------------------------------------------------------------------------------------------------------------------?EEEEEEEEETTTTEEEEEEEEEGGG??????????????----------------------------------------------------------------- 2P04|A PF07702.8_UTRA_seed 168 184 !Q:3,5|10,13|22,25|34,36|39,39|41,41|52,54|70,70|73,73|75,81|84,84|87,92|95,97|105,105|110,113|117,118|125,125|129,131|141,144|147,149|153,154|165,166|168,168|182,183 Q:0,2|6,9|14,21|26,33|37,38|40,40|42,51|55,69|71,72|74,74|82,83|85,86|93,94|98,104|106,109|114,116|119,124|126,128|132,140|145,146|150,152|155,164|167,167|169,181 HTT??-EEEE----EEEEEEEE?--?HHHHHHHT?-?SS?E-EEEEEEEEEE---TTEEEEEEEEEEEGG-GT?S??-----HH-HH------TS?--HHHHHHH-HHTS---?EEE--EEEEEE-EEE?-?HHHHHHHTS---?TT--?EEE--EEEEEEEETT--S?EEEEEEEEEETTT?? 3DDV|A PF07703.9_A2M_N_2_seed 184 337 !Q:3,5|7,11|13,15|18,18|26,27|30,31|34,42|47,48|50,50|56,56|58,58|67,126|130,131|134,134|136,174|181,182|188,189|196,196|198,241|245,249|255,255|258,260|262,267|270,271|276,276|279,281|283,286|289,289|297,298|300,319|322,322|330,330 Q:0,2|6,6|12,12|16,17|19,25|28,29|32,33|43,46|49,49|51,55|57,57|59,66|127,129|132,133|135,135|175,180|183,187|190,195|197,197|242,244|250,254|256,257|261,261|268,269|272,275|277,278|282,282|287,288|290,296|299,299|320,321|323,329|331,336 EEE---E???--S???TT?EEEEEEE--EE??TT---------TGGG??E-EEEEE-E?SSSEEEEE------------------------------------------------------------EEE??TT?S?--------------------------------------EEEEEE??GGGSS-?EEEEEE-E?----------------------------------------???TTS-????EEEEE-EE???S-??---SS??EEEE-SS???S-???TT?EEEEEEE--E-------------------?TT?BEEEEEE?HHHHTT 4FXG|A PF07705.6_CARDB_seed 72 153 !Q:0,5|9,16|21,21|25,25|35,35|37,37|41,41|45,46|48,49|54,62|71,73|79,89|91,91|93,93|96,96|106,110|112,120|125,125|131,131|134,134|137,139|142,144 Q:6,8|17,20|22,24|26,34|36,36|38,40|42,44|47,47|50,53|63,70|74,78|90,90|92,92|94,95|97,105|111,111|121,124|126,130|132,133|135,136|140,141|145,152 ??---?EEE--------EEEE?SEE?TTSEEEEEE-E-EEE?SSS?-B??EEEE---------EEETTEEE---EEEEE-----------S?B?BT?EEEEEEEEE??--?S?--------SEEE-EEEEE?TT?SS??-SS---GGGSEEEE 2KUT|A PF07707.10_BACK_seed 81 108 !Q:0,0|11,11|13,13|24,25|27,29|36,36|41,41|53,53|56,58|74,107 Q:1,10|12,12|14,23|26,26|30,35|37,40|42,52|54,55|59,73 ?HHHHHHHHHH-T?HHHHHHHHTT??S???SSHHHH-HHHT-STTHHHHHHHH?TT???SSGGGGHHHHHHHHH??????????????-?????-????????????? 4AP2|A PF07710.6_P53_tetramer_seed 28 47 !Q:0,2|5,12|14,15|41,41|45,47 Q:3,4|13,13|16,40|42,44 ???SS-----???B??EEEESHHHHHHHHHHHHHHHHHHHH-TSS??- 1OLH|A PF07711.6_RabGGT_insert_seed 4 104 !Q:1,1|23,23|30,30|41,44|46,46|51,52|61,62|94,94|101,102 Q:0,0|2,22|24,29|31,40|45,45|47,50|53,60|63,93|95,100|103,103 S?EEEEEEETTTTEEEEEEEEEE?TTBTTB?EEEEESSSEE????B?TTSS??SEEEEEEE??GGGTSTTSSEEEEEEEETTTTEEEEEEEETT?SEEEEE??S 1DCE|A PF07714.12_Pkinase_Tyr_seed 145 484 !Q:4,4|7,14|23,36|40,40|43,43|51,58|60,61|63,64|68,70|77,77|86,88|92,93|99,110|114,120|126,127|130,133|143,245|249,249|269,270|273,273|275,276|284,289|291,303|305,307|311,313|316,316|320,327|329,331|334,336|343,344|350,354|361,374|394,396|398,411|415,417|421,428|434,434|438,446|450,450|455,455|458,458|464,464|471,472|477,479 Q:0,3|5,6|15,22|37,39|41,42|44,50|59,59|62,62|65,67|71,76|78,85|89,91|94,98|111,113|121,125|128,129|134,142|246,248|250,268|271,272|274,274|277,283|290,290|304,304|308,310|314,315|317,319|328,328|332,333|337,342|345,349|355,360|375,393|397,397|412,414|418,420|429,433|435,437|447,449|451,454|456,457|459,463|465,470|473,476|480,483 EEEE-EE????????EEEEEEET?-------------STT?TT?EEEEEEE??--?---T--T??HHH---HHHHHH-HHHHHHHH???TTB??EEEEE?-----------SSS?-----?EEEEE??TT?---BHHHHHHHT??????----------------------------------------------------------------------???????-?------------??????HHH-HHHHHHHHHHHHHHHHHTT--EE?S??SGGGEEE?-----T-------------T?-?EEE???SS?EET--------T???TT--?TTTTTT--SBGGG?---?HHHHHT??----------??HHHHHHHHHHHHHHHHTTS?-?S--------------STT?-?HHH--------HHHHH-HTT??--???-?TTS?HHHH-HH-HHHHT?SSGGGS??HHHH---HHHH 3B8R|A PF07715.10_Plug_seed 742 259 !Q:4,4|11,16|18,18|22,22|27,31|40,45|47,48|51,56|60,85|89,89|93,101|103,104|107,117|123,128|130,149|158,158|162,178|182,190|192,194|196,206|210,211|213,214|216,222|224,228|230,231|241,241|243,244|247,247|250,250|252,252 Q:0,3|5,10|17,17|19,21|23,26|32,39|46,46|49,50|57,59|86,88|90,92|102,102|105,106|118,122|129,129|150,157|159,161|179,181|191,191|195,195|207,209|212,212|215,215|223,223|229,229|232,240|242,242|245,246|248,249|251,251|253,258 EGGG?SSEEEE------E?HHH-HHSS--?-?SSTHHHHT------T--ST------TEE--------------------------EEE?SSS---?-----E--EE-----------EETTB-----?G--------------------GGEEEEET-TEE???--------------TTT?-------?S???G-----------GGS--S--S-?-----G-----G--GEEEEEEEE-S??HH-HH?T-TTTSEE 1XKW|A PF07716.10_bZIP_2_seed 48 58 !Q:10,10|45,47 Q:0,9|11,44|48,57 TSHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHHHHHH 1S9K|D PF07717.11_OB_NTP_bind_seed 118 396 !Q:7,57|61,63|65,82|85,136|138,138|155,191|194,206|209,213|216,217|222,253|256,258|263,263|265,265|269,271|273,283|287,289|291,311|321,333|335,342|345,345|351,374|378,380|388,392|396,396 Q:0,6|58,60|64,64|83,84|137,137|139,154|192,193|207,208|214,215|218,221|254,255|259,262|264,264|266,268|272,272|284,286|290,290|312,320|334,334|343,344|346,350|375,377|381,387|393,395 HHHHHHH---------------------------------------------------HHT---T???---------??---?TT---------------------------------------------------?T-HHHHHHHHHHHGGGEE-------------------------------------EE?------------SS-----SS--EEET--------------------------------TT??-EEEE?T-TST---T-----------TTS??-S---------------------EEEEEEEEE-------------S--------SS-EEEEE------------------------EEE?-?HHHHHHH-?---TTT- 2XAU|A PF07719.12_TPR_2_seed 369 35 !Q:15,15|17,17|31,31|34,34 Q:0,14|16,16|18,30|32,33 HTTSSSSSSSTTTTT?H-HHHHHHHHHHHHH?TT? 4HOU|A PF07720.7_TPR_3_seed 18 39 !Q:7,9|18,18|26,27|35,35|38,38 Q:0,6|10,17|19,25|28,34|36,37 HHHHHHH---HHHHHHTT?HHHHHHH--HHHHHHH?TT? 2XCC|A PF07721.9_TPR_4_seed 143 26 !Q:15,15 Q:0,14|16,25 HHHHHHHHHHHHHHT?HHHHHHHHHH 2PL2|A PF07722.8_Peptidase_C26_seed 45 261 !Q:0,0|6,27|39,39|45,50|61,61|67,69|71,74|80,84|87,91|110,111|128,129|137,145|149,153|155,157|159,159|161,162|165,166|172,179|188,196|199,201|205,206|208,208|210,210|215,224|235,235|237,238|247,247|249,249|251,251|258,258 Q:1,5|28,38|40,44|51,60|62,66|70,70|75,79|85,86|92,109|112,127|130,136|146,148|154,154|158,158|160,160|163,164|167,171|180,187|197,198|202,204|207,207|209,209|211,214|225,234|236,236|239,246|248,248|250,250|252,257|259,260 ?EEEEE?????-???????????-????HHHHHHHHHHT?EEEEE???--?GGGHHHHHHT?SEEEE???S-???GGGGT????-TT?????HHHHHHHHHHHHHHHHTT??EEEETHHHHHHHHHTT??EESSGGG---------SSS?????B-??S?T--TS??EEEEE?-------TTSSGGGT?-----?--TT---EEE??B?S?EESS--------??SSEEEEEEET-T??EEEEEESS?S-S?EEEESS?GG 1WL8|A PF07724.9_AAA_2_seed 139 257 !Q:1,1|10,10|18,26|37,50|54,55|67,74|79,79|84,85|102,105|108,108|117,118|122,122|124,138|155,163|168,168|173,173|183,183|185,185|191,195|200,222|245,245|247,247|255,255 Q:0,0|2,9|11,17|27,36|51,53|56,66|75,78|80,83|86,101|106,107|109,116|119,121|123,123|139,154|164,167|169,172|174,182|184,184|186,190|196,199|223,244|246,246|248,254|256,256 S?SEEEEEES?SSTTHHH---------HHHHHHHHHH--------------SSS??EEEEEGGGTTS--------SSSS?TTSS??SSTHHHHHHTHHHHHH----HH?SSSEEEEE??SSS?T---------------HHHHHHHHHHHHSEEE---------ETTT-EEEE?SSSEEEEEE?S?GGGTT?????SSST-----------------------TTTTTTHHHHHHHSTTTSTTSS?H-HHHTTSS?E 3J3U|A PF07726.6_AAA_3_seed 55 138 !Q:0,0|6,8|24,25|31,33|36,37|45,45|53,56|64,64|67,67|80,80|94,94|106,107|110,110|117,117|120,121|123,128 Q:1,5|9,23|26,30|34,35|38,44|46,52|57,63|65,66|68,79|81,93|95,105|108,109|111,116|118,119|122,122|129,137 ?EEEES???HHHHHHHHHHHHHTT??EEEEE-??TT??HHHHHEE-EEEETTT----TEEEEEE?TT?SSEEEEETGGGS?HHHHHHHHHHHHH-SEEEETTEEEE??SS?EEEEEE?TT??S??????HHHHTTSSE 1IQP|A PF07728.9_AAA_5_seed 34 187 !Q:5,6|24,27|29,30|36,37|40,41|47,48|50,76|78,79|86,86|97,99|117,119|126,155|164,174|177,177|186,186 Q:0,4|7,23|28,28|31,35|38,39|42,46|49,49|77,77|80,85|87,96|100,116|120,125|156,163|175,176|178,185 EEEEE??SSSSHHHHHHHGGGGBS----S??EEEEE??TT??HHHHH??B??---------------??????????B??TTSGGG?SEEEEESGGG??-HHHHHHHHHHHHSSEEE--?SSSEEE???--------------------------?EEEEEESS??--------?TT?TTHHHHTT? 4AKH|A PF07729.7_FCD_seed 317 227 !Q:1,3|5,7|9,11|14,16|22,26|31,31|33,34|38,39|42,43|45,55|66,72|78,88|92,104|120,122|127,137|139,140|151,151|153,154|162,176|179,181|183,185|188,189|192,192|201,201|203,203|211,218|223,223 Q:0,0|4,4|8,8|12,13|17,21|27,30|32,32|35,37|40,41|44,44|56,65|73,77|89,91|105,119|123,126|138,138|141,150|152,152|155,161|177,178|182,182|186,187|190,191|193,200|202,202|204,210|219,222|224,226 H---H---H---HH---HHHHH-----HHHH-H--HHG--GG??H-----------HHHHHHHHHH-------HHHHH--------???HHH-------------HHHHHHHHHHHHTTT???HHHH-----------H--HHHHHHHHHH-H--HHHHHHH---------------HH???S???HH--HH-HHHHHHHT-T?HHHHHHH--------HHHH-HHH 3C7J|A PF07730.8_HisKA_3_seed 191 86 !Q:0,3|31,35|38,38|41,51|80,84 Q:4,30|36,37|39,40|52,79|85,85 ????HHHHHHHHHHHHHHHHHHHHHHHHHHT-----TT?HH-----------HHHHHHHHHHHHHHHHHHHHHHHHHHHH--???H 3EHJ|A PF07731.9_Cu-oxidase_2_seed 127 222 !Q:0,3|6,6|14,37|44,44|49,49|53,53|58,58|61,61|70,77|81,108|116,117|124,128|133,149|154,158|161,161|170,170|172,175|177,177|185,190|192,192|200,201|203,204|211,211|218,218 Q:4,5|7,13|38,43|45,48|50,52|54,57|59,60|62,69|78,80|109,115|118,123|129,132|150,153|159,160|162,169|171,171|176,176|178,184|191,191|193,199|202,202|205,210|212,217|219,221 ????SS?HHHHHTT------------------------SGGGTT?GGGG?SSS?EEEE?TT?EEEEEEEE-------?SSS---------------------------?EEEEETT??EEEEEE?????GGGT????-----------??BTTB?????SS?EEESEEEE?T----T?EEEEEEE?---?-S?EEEEEEE??H--HHHHTT?EEEEEE?HHH 3T71|A PF07732.10_Cu-oxidase_3_seed 121 131 !Q:7,7|12,15|27,29|36,36|45,48|51,53|55,55|61,63|66,66|71,72|78,79|81,81|83,83|85,85|93,98|106,106|110,112|116,116|119,119|127,129 Q:0,6|8,11|16,26|30,35|37,44|49,50|54,54|56,60|64,65|67,70|73,77|80,80|82,82|84,84|86,92|99,105|107,109|113,115|117,118|120,126|130,130 EEEEEEE?SSSB?---EEEEEETTBSS???EEEETT?EEEEEEEE??--SS??-B?EEETT???TT?GGGS??BTTTB??B?T-T?EEEEEEE???--?EEEEEEE?STT---GGG-GT?EEEEEEE???S 3T71|A PF07733.7_DNA_pol3_alpha_seed 89 687 !Q:11,12|17,19|24,25|32,44|65,70|72,72|89,92|95,96|98,98|100,101|107,107|116,117|119,119|123,165|168,169|175,175|179,186|205,205|207,212|220,220|224,225|238,244|246,247|259,261|263,266|268,269|271,282|289,296|306,306|308,316|329,331|334,334|339,339|342,343|348,349|352,353|358,359|362,363|367,393|395,395|404,404|410,410|417,419|433,449|452,455|461,492|494,495|499,501|503,504|506,506|511,511|517,534|553,555|575,580|593,597|600,602|605,605|609,611|613,613|616,616|626,628|638,639|644,646|660,662|672,676|686,686 Q:0,10|13,16|20,23|26,31|45,64|71,71|73,88|93,94|97,97|99,99|102,106|108,115|118,118|120,122|166,167|170,174|176,178|187,204|206,206|213,219|221,223|226,237|245,245|248,258|262,262|267,267|270,270|283,288|297,305|307,307|317,328|332,333|335,338|340,341|344,347|350,351|354,357|360,361|364,366|394,394|396,403|405,409|411,416|420,432|450,451|456,460|493,493|496,498|502,502|505,505|507,510|512,516|535,552|556,574|581,592|598,599|603,604|606,608|612,612|614,615|617,625|629,637|640,643|647,659|663,671|677,685 HHHHHHHHHHH--HHHH---HHHS-?SSTTHH-------------HHHHHHHHHHHHHHHHHHHT------T?HHHHHHHHHHHHHHHH----SS??B?S??TTGGG?HHHHHTTS??S?TTT-------------------------------------------TT??HHHHS?TTS????????EEEGGGHHHHHHHHHHHH?G------GGEEEEE?EEE??HHHHHHHHHHHT-------T??HHHHHHHHTTS???T----T??H------------HHHHHH?-------THHHHHHHH?H---------HHHHHHHHHHHH---TT?EEEE?SS??EEEE-?SS-?GGGT??EE??TTS--------------------------?S?EEEEEHHH-HHHTT?EEEEEE???HHHHHHHHHHHHH-----------------HH----HHHTT?----------???-----?------------G--GGS?--S??H-HHHH-HHHHT----------------??TTSTTTTSHHHHHHHHHH???SSHHHHHHHHHSSHHHHHT------THHHHHHHHHTT-----SS???SB?SSS---B?TT?HHHHTTTTT???BHHHHHHHH--HHTT???SHHHHHHHHHHHH-??HHHHHHHHH-----HHHHHHHHH? 4IQJ|A PF07736.6_CM_1_seed 57 123 !Q:0,0|9,9|34,35|37,37|48,48|51,52|55,55|64,65|67,68|78,81|85,86|96,97|100,100|102,103|106,108|111,111|117,122 Q:1,8|10,33|36,36|38,47|49,50|53,54|56,63|66,66|69,77|82,84|87,95|98,99|101,101|104,105|109,110|112,116 ?EEEEEEEE?SSSSHHHHHHHHHHHHHHHHHHTT??G-GGEEEEEEEE?TT??SS?THHHHHHT--T?-TTSEEEEEE????TTS??SEEEEEEEE??SS?G--GG???EE?GGGGG?????? 1COM|A PF07737.6_ATLF_seed 4 244 !Q:0,8|13,15|17,17|32,32|40,40|45,45|50,50|53,54|61,61|66,68|70,72|76,79|83,83|88,89|93,93|98,101|104,104|128,128|134,139|150,160|166,174|178,178|183,185|188,189|214,214|217,217|225,227 Q:9,12|16,16|18,31|33,39|41,44|46,49|51,52|55,60|62,65|69,69|73,75|80,82|84,87|90,92|94,97|102,103|105,127|129,133|140,149|161,165|175,177|179,182|186,187|190,213|215,216|218,224|228,243 ??-??????EEES???S?TTTHHHHHHHHTTS?HHHHHHH-HHTT?EEEE?SS??STTSTT?SSSS???S???SSS????GGG?SEEE??SSS?EEEE??-?SS?SSSSGGGHHHHHHHHHTTTSTTS-SSSSS-??--?HHHHHHHHTT-----------TSSSS???-----?TTT?STTT???SS??STTTTTTTTTTTTTTHHHHHHHHH?SS?SHHHHHS--?HHHHHHHHHHHTTHHH 1ZXV|A PF07738.8_Sad1_UNC_seed 25 158 !Q:4,6|14,18|22,22|30,30|50,52|60,62|67,67|77,77|81,89|97,99|103,103|110,110|113,116|118,124|133,134|137,140|142,142|149,149 Q:0,3|7,13|19,21|23,29|31,49|53,59|63,66|68,76|78,80|90,96|100,102|104,109|111,112|117,117|125,132|135,136|141,141|143,148|150,157 EEEE???GGGGGSS?---?STT?SEEEETT?EEEEEEEEEEEEEEEEEEE???GGGSGGG??-TTSB?EEEEEEESS?TTS?-------?EEEEEEE?-?TTS?SEEEEE?SS?--?S?-----?EEEEEEEE??BS----S?SSEEEE?EEEEEEEE 4DXS|A PF07739.8_TipAS_seed 164 169 !Q:0,45|50,53|69,71|74,74|89,89|91,93|98,105|108,115|121,123|128,130|134,134|143,143|146,150|153,153|157,157 Q:46,49|54,68|72,73|75,88|90,90|94,97|106,107|116,120|124,127|131,133|135,142|144,145|151,152|154,156|158,168 ????????????--???????????----------?????-?????TTHH----HHHHHHHHHHHHHHT-??TT?HHHHHHHHHHHHHH-H---HHSS?-----??HH--------HHHHH---HHHT---TST-HHHHHHHG-GG-----ST-THH-HHHHHHHHHHH 1NY9|A PF07740.7_Toxin_12_seed 31 41 !Q:0,3|6,6|8,9|14,14|16,18|24,25|27,30|36,38 Q:4,5|7,7|10,13|15,15|19,23|26,26|31,35|39,40 ????SS?B??SSSS-S?--TTEES??S----SSSSB--?EE 1EMX|A PF07742.7_BTG_seed 31 142 !Q:20,25|48,50|62,62|64,65|69,71|74,75|82,96|102,103|112,112|133,134|141,141 Q:0,19|26,47|51,61|63,63|66,68|72,73|76,81|97,101|104,111|113,132|135,140 SHHHHHHHHHHHHHHHHHHS?---??HHHHHHHHHHHHHHHHHHHTTS-??TTSTTTTHHHH?E--EES---SS??HHHHHH---------------HHTTT??HHHHHHHS?SSEEEEEETTEEEEEESTTS-?EEEEEE? 2D5R|B PF07743.8_HSCB_C_seed 143 104 !Q:0,2|4,5|25,27|32,32|58,60|62,69|72,72|84,90|96,96 Q:3,3|6,24|28,31|33,57|61,61|70,71|73,83|91,95|97,103 ???H--HHHHHHHHHHHHHHHGGGS---SSHH-HHHHHHHHHHHHHHHHHHHHHHHHH---H--------TT?HHHHHHHHHHH-------HHHHH-HHHHHHH 3UO2|A PF07744.8_SPOC_seed 58 219 !Q:4,4|10,10|23,26|35,92|96,96|101,101|119,123|131,139|141,142|155,163|178,178|180,185|191,192|195,196|198,210|217,218 Q:0,3|5,9|11,22|27,34|93,95|97,100|102,118|124,130|140,140|143,154|164,177|179,179|186,190|193,194|197,197|211,216 EEEE-EEETT-EEEEEEEEEEEE?---HHHHHHHS???-----------------------?---------------------------????EEE?EEEE?SHHHHHHHHHHTSSTTT-----EEEEEEE---------E??SSHHHHHHHHHH---------HHHHTHHHHHHHTE-E------EEEEE??TT??S-----------??EEEEEE-? 1OW1|A PF07745.8_Glyco_hydro_53_seed 16 481 !Q:5,5|11,51|57,63|66,70|78,78|81,82|89,89|91,92|94,100|103,104|106,106|110,112|128,128|132,132|136,136|141,142|146,150|156,158|166,167|180,180|185,186|196,196|199,199|203,214|216,217|235,244|246,246|256,257|275,276|278,284|292,292|294,296|300,311|313,317|332,333|341,343|345,345|347,348|353,354|358,358|361,363|365,367|369,369|390,397|407,407|410,412|415,415|425,425|431,432|436,436|443,443|446,447|453,453|456,456|458,458|462,462|466,468|472,472|474,474 Q:0,4|6,10|52,56|64,65|71,77|79,80|83,88|90,90|93,93|101,102|105,105|107,109|113,127|129,131|133,135|137,140|143,145|151,155|159,165|168,179|181,184|187,195|197,198|200,202|215,215|218,234|245,245|247,255|258,274|277,277|285,291|293,293|297,299|312,312|318,331|334,340|344,344|346,346|349,352|355,357|359,360|364,364|368,368|370,389|398,406|408,409|413,414|416,424|426,430|433,435|437,442|444,445|448,452|454,455|457,457|459,461|463,465|469,471|473,473|475,480 EEEEE?TTHHH-----------------------------------------HHHTT??--???TT?????HHHHHHH-TT??EEEEEE?S??B?------TT??B?STT???HHHHHHHHHHHHHTT?EEE-EEE?SSSS??SSS?????GGGTT?-?HHHHHHH--HHHHHHHHHHHH-HHTT??EEEEEESSS?SS?BTT------------B??HHHHHHHHHHHHHHHHH----------H?TTSEEEEEE??TTSTTHHHHHHHHHHHT--T----???SEEEEEE?T---TTS?----------?H-----HHHHHHHHHHHHHH??EEEEEEE???S?S??SSSS??SSS?TT---S???S?SSHHHHHHHHHHHHHHHHTT?-------TTEEEEEEE?TT???SS?GGGHHHHHH-HHHHH??SSB?GGGTTT?TT--THHHH?BS?S?GGG-SSB?--TTS?B?GGGGHH 1HJQ|A PF07746.6_LigA_seed 40 91 !Q:8,8|20,20|30,31|42,42|51,52|65,66|77,78|80,80 Q:0,7|9,19|21,29|32,41|43,50|53,64|67,76|79,79|81,90 HHHHHHHT-TSHHHHHHHHH?HHHHHHTTT??HHHHHHHHHT?HHHHHHTT??HHHHHHHHHHTT??HHHHHHHTTT--S?HHHHHHHHHT 1B4U|A PF07747.6_MTH865_seed 6 81 !Q:15,15|28,28|33,37|42,44|50,50|54,54|60,60|72,75|79,80 Q:0,14|16,27|29,32|38,41|45,49|51,53|55,59|61,71|76,78 HHHHHHHHHHHTTSS-STTBHHHHHHHH?TTSS?????BTTB???TTTTG-GGS?GGGSB?SHHHHHHHHHH----HHH?? 1IIO|A PF07748.8_Glyco_hydro_38C_seed 45 903 !Q:7,7|11,11|22,22|24,24|32,49|52,52|64,72|93,93|98,98|110,110|113,114|117,118|122,122|128,128|131,148|151,151|154,155|159,162|167,167|171,173|178,178|181,181|183,183|194,195|198,206|215,236|241,252|255,263|267,267|270,281|283,299|305,305|308,308|311,312|326,336|342,342|349,351|353,353|355,355|357,359|370,395|413,414|418,427|432,432|434,444|454,454|457,459|462,468|476,476|481,491|493,494|505,562|567,571|575,576|578,578|580,585|597,598|602,624|627,627|631,633|646,647|652,653|655,655|658,659|661,663|666,667|671,671|675,681|690,714|717,717|719,719|722,730|736,736|743,758|760,770|785,785|789,789|793,882|885,885|889,894|897,897 Q:0,6|8,10|12,21|23,23|25,31|50,51|53,63|73,92|94,97|99,109|111,112|115,116|119,121|123,127|129,130|149,150|152,153|156,158|163,166|168,170|174,177|179,180|182,182|184,193|196,197|207,214|237,240|253,254|264,266|268,269|282,282|300,304|306,307|309,310|313,325|337,341|343,348|352,352|354,354|356,356|360,369|396,412|415,417|428,431|433,433|445,453|455,456|460,461|469,475|477,480|492,492|495,504|563,566|572,574|577,577|579,579|586,596|599,601|625,626|628,630|634,645|648,651|654,654|656,657|660,660|664,665|668,670|672,674|682,689|715,716|718,718|720,721|731,735|737,742|759,759|771,784|786,788|790,792|883,884|886,888|895,896|898,902 EEEEEEE?SSS?EEEEEEEEES?S?EEEEETT----------------??EE?EEEEEEEEEEE---------ETTTTEEEEEEEEEEEEEEE-EEEE?TTEEEEEEEEE?SS??TT--EEE?EEEEE?SS??????------------TT?SS??EEE????EEEE?TTS--?EEEE?TT-S?EEEEESSSSS??EE---------EEEEEEEE??-------------------?SSSS?---------??SS???-----?SSS?EE--------????S??---------------EEEEE?SS?EE--EEEEETTEEEEEE-----------ESSSS?EEEEEE?-?T-T?T---TEEEEEEEEE????----------------------TTEEEEEETTTEEEEEE??TTS?---------GGGG?E-----------EESSEEEEE?SS---EE-------EEEEESS?EEEE?---------?S--TTEEEEEEEE----------------------------------------------------------EBSS?---?SSS??S?B??-???EEEEEEEEEEE?-TTS??-------------------??TT?SEE???HHHHHHHHHHHS??EEEE--E?SS??T---TB?-SEE?TTS?-?--??TTEEEEEE-------------------------EE?S?TT?--------SSEEE-EEEEEE????----------??S?-?????????GGGSSSSEEEEEEE?TTS?SEE------------------------------------------------------------------------------------------EE?GGG??????TT?EEEEE 1HTY|A PF07749.7_ERp29_seed 36 116 !Q:1,2|16,17|35,35|37,42|47,47|64,71|88,92|94,95|97,97 Q:0,0|3,15|18,34|36,36|43,46|48,63|72,87|93,93|96,96|98,115 T??HHHHHHHHHHHHS?-SHHHHHHHTTHHHHHTT?S?-----HHHH-HHHHHHHHHHHHHHHS?-------TTSHHHHHHHHHHHHH-----H??S?HHHHHHHHHHHHHHTTSS 2C0G|A PF07752.6_S-layer_seed 14 336 !Q:3,4|7,18|22,22|26,26|34,35|41,58|60,61|67,69|71,73|78,78|81,81|88,88|101,110|113,114|134,134|136,148|153,153|158,159|167,167|171,171|177,190|201,201|225,225|229,232|244,244|249,249|264,264|267,267|279,279|283,283|286,287|290,291|296,296|309,309|312,312|315,316|321,322|334,335 Q:0,2|5,6|19,21|23,25|27,33|36,40|59,59|62,66|70,70|74,77|79,80|82,87|89,100|111,112|115,133|135,135|149,152|154,157|160,166|168,170|172,176|191,200|202,224|226,228|233,243|245,248|250,263|265,266|268,278|280,282|284,285|288,289|292,295|297,308|310,311|313,314|317,320|323,333 EEB??EE------------SSS?EEE?TTTBTTS??BTTTT------------------B??EEEEE???B---TTEE?TT?EEEEEE?EEEEEEEEEGGG----------TE--EEEEEEEETTEEEEESSTT?T-------------TEEE?EEEE--EEEEEEE-ETT?EEEEE--------------TTEEEEEEEE?TTSSEEEEEEEETTEEEEEEEEE?SSS---?GGGGEEEEEES?BTTB?SEEEEEEEEEEEEE?SS?EEEEEEEEEEE?GGG?EE??TT??BTTB?EEEEETTEEEEE?SS?EE??TTEE--EEEETTEEEEE?? 3U2G|A PF07755.6_DUF1611_seed 79 373 !Q:1,3|10,10|16,20|22,24|33,35|37,37|40,41|47,54|56,57|72,72|77,77|81,89|92,92|99,100|102,104|106,107|113,116|119,124|129,139|141,141|173,174|179,180|188,188|191,191|193,194|217,221|223,224|230,234|237,239|243,250|260,261|272,273|275,275|278,278|281,283|286,289|305,307|311,314|320,320|323,323|327,329|333,333|346,352|354,354|357,357|362,365|368,369 Q:0,0|4,9|11,15|21,21|25,32|36,36|38,39|42,46|55,55|58,71|73,76|78,80|90,91|93,98|101,101|105,105|108,112|117,118|125,128|140,140|142,172|175,178|181,187|189,190|192,192|195,216|222,222|225,229|235,236|240,242|251,259|262,271|274,274|276,277|279,280|284,285|290,304|308,310|315,319|321,322|324,326|330,332|334,345|353,353|355,356|358,361|366,367|370,372 E?--GGGTTS?HHHHH?-??-S???EESSHHHH---G-GG??SEEEE????????S?-GGGHHHHHHHHHTT?EEEE?SSS-??------TT?HHHHHH??T---T??EEETT??-?SS?-????SGGG-----------G?SSEEEEEEESSSSSSHHHHHHHHHHHHHHTT??EEEE??SHHHHHH-HS?S??GGGSBHHHHHHHHHHHHHHHTT-----T?-SEEEE?????TT---STT-??-----THHHHHHHH??SEEEEEEETT??B?SS?TT---SB?-??HHHHHHHHHHHHHTT---TTS????EEEEE-EE?TTS?--HHH-HHHHHHHHHHHH------?S?EE?HHHH--?-SH--HHH 2OBN|A PF07764.6_Omega_Repress_seed 2 71 !Q:0,25|48,49|69,70 Q:26,47|50,68 ??????????????????????????EEEEEEEHHHHHHHHHHHHHHT??HHHHHHHHHHHHHHHHSTT?? 2BNW|A PF07766.8_LETM1_seed 13 294 !Q:0,114|133,137|141,141|148,149|162,162|165,165|168,168|184,184|188,188|191,192|196,196|209,212|240,241|246,246|259,261|264,265|284,286 Q:115,132|138,140|142,147|150,161|163,164|166,167|169,183|185,187|189,190|193,195|197,208|213,239|242,245|247,258|262,263|266,283|287,293 --------------------------?-------------------------------------------------------------???-???????????????----????HHHHHHHHHHHHHHHHTT?????GGG?SSHHHH--HHHHHHHHHHHT?BT-TB?EEEEHHHHHHHHTTS?HHH-HH--HHS?HHHHHHHHHHTT????SSHHHHHHHHHHHHHHHHHHHHHHHHH-?GGGS?HHHHHHHHHHTT???TT??HHHHHHHHHHHHHHHHTS???HHHHHHH 3SKQ|A PF07776.10_zf-AD_seed 98 126 !Q:1,1|5,25|27,28|38,38|41,51|53,61|71,71|74,84|87,87|90,90|92,93|95,95|118,118|125,125 Q:0,0|2,4|26,26|29,37|39,40|52,52|62,70|72,73|85,86|88,89|91,91|94,94|96,117|119,124 B?TTT??-------------------B??SSTTEEESS?SS----------?S?-------?SHHHHHHHH?SS???--------SS?SS?S--E-EEHHHHHHHHHHHHHHHHHHHH-HHHHHH? 1PZW|A PF07804.7_HipA_C_seed 175 133 !Q:1,2|12,13|17,21|25,35|38,40|43,43|50,61|64,65|70,80|99,103|107,107|113,115|119,119|121,123|125,125|128,132 Q:0,0|3,11|14,16|22,24|36,37|41,42|44,49|62,63|66,69|81,98|104,106|108,112|116,118|120,120|124,124|126,127 E??EEEHHHHTT??GGG----?SGG-----------GT???HH-HHHHHG------------GG--STTH-----------HHHHHHHHHHHHHHHHHT?????GGG?EEEEE---TTT-E---E-EE????? 3FBR|A PF07805.7_HipA_N_seed 170 138 !Q:0,2|9,10|13,13|15,31|36,40|44,47|52,52|54,55|57,59|61,63|66,70|72,72|83,83|87,87|91,98|102,105|111,127|134,134 Q:3,8|11,12|14,14|32,35|41,43|48,51|53,53|56,56|60,60|64,65|71,71|73,82|84,86|88,90|99,101|106,110|128,133|135,137 ???SSSSEE??EE?S-----------------SSEE?---?EET????EEEE?S?-S???S---SS?????S?HHHHHHHHHH-HHH-HTT?-???--?EEE----EESSS----------------?EEEEEE?TTE 3FBR|A PF07809.6_RTP801_C_seed 9 137 !Q:9,9|12,12|15,16|51,52|64,64|68,70|79,80|83,90|92,104|108,117|120,124|126,126|134,136 Q:0,8|10,11|13,14|17,50|53,63|65,67|71,78|81,82|91,91|105,107|118,119|125,125|127,133 HTTEESSSS?EE?EE??HHHHHHHHHHHHHHHTTSTTGGGGEEEEEEEEET--TEEEEEEEEES?TTS???EEEEEEEE??TT-???????S-----------??TTS??-----???EE?---?S?EEEEEEE??? 3LQ9|A PF07813.7_LTXXQ_seed 46 124 !Q:0,11|13,15|34,46|56,64|68,68|71,72|81,82|93,96|112,112 Q:12,12|16,33|47,55|65,67|69,70|73,80|83,92|97,111|113,123 ????????????S???TTHHHHHHHHHHHHSSSS???---------?TTHHHHHHH---------HHT?SS??HHHHHHHH--GGGSHHHHHH----HHHHHHHHHHHHTTS?HHHHHHHHHHT 3O39|A PF07814.8_WAPL_seed 13 456 !Q:6,6|9,12|14,15|31,31|35,35|64,65|79,79|81,106|123,124|128,131|144,186|205,217|221,221|232,240|249,249|275,283|288,291|316,316|350,352|355,359|363,364|395,400|429,429|451,451 Q:0,5|7,8|13,13|16,30|32,34|36,63|66,78|80,80|107,122|125,127|132,143|187,204|218,220|222,231|241,248|250,274|284,287|292,315|317,349|353,354|360,362|365,394|401,428|430,450|452,455 HHHHHT?SS????S??HHHHHHHHHHHHHTS-TTS?HHHHHHHHHHHHHHTTSHHHHHHHHHTT?-HHHHHHHTTTGGG?H--------------------------HHHHHHHHHHHHHTTS??TTT?--?HHHHHHHHHHHH------------------------????---?????---????TTHHHHHHHHHHHHHHHH--------?????GGG?SHHHHHHHHH---------HHHTSTTT?SHHHHHHHHTTHHHHHHHHHHHHHH---------HHHS-???HHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT???TT?????SSS??TTSHHHHHHHHHHHHHHHHHHHHHHHHHSS?-----HHHHHHHHTSTTHHHHHHHHHHTGGGGS?GGGHHHHHHHHHHHHHHHHSS?HHHH 4K6J|A PF07815.9_Abi_HHR_seed 11 85 !Q:20,20|23,29|33,34|37,53|63,84 Q:0,19|21,22|30,32|35,36|54,62 HHHHHHHHHHHHHHHHHHTT?EE???????SEE??SS----?????????????TTTTTTTTT?????----------------- 3P8C|F PF07817.8_GLE1_seed 22 309 !Q:19,19|40,41|45,45|59,68|75,75|79,82|103,103|107,107|109,110|122,122|143,143|148,151|153,159|170,171|173,174|178,178|180,181|203,205|213,239|242,242|247,248|259,259|262,269|271,272 Q:0,18|20,39|42,44|46,58|69,74|76,78|83,102|104,106|108,108|111,121|123,142|144,147|152,152|160,169|172,172|175,177|179,179|182,202|206,212|240,241|243,246|249,258|260,261|270,270|273,308 HHHHHHHHHHHTHHHHHHS?HHHHHHHHHHHHHHTTHHHH??SBH-HHHHHHHHHHHHH----------HHTTTT-SHH----HHHHHHHHHHHHHHHHHHHH-HHH?G--GGHHHHHHHHH-HHHHHSTTHHHHHHHHHHHH?GGGG----T?????--SSHHHHHHTT??B?-TTS?B??HHHHHHHHHHHHHHHHHHHHS???TTTTTTS-------------------------??SS?THHH--HHHHHHHHTS?GG--------G??HHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHTH 3RRN|B PF07819.8_PGAP1_seed 20 379 !Q:0,5|10,14|17,18|21,30|40,52|56,126|128,128|133,134|141,143|145,150|166,182|184,184|186,186|206,206|208,214|225,226|229,231|233,235|246,269|273,275|288,290|296,307|321,321|324,327|338,357|359,359|364,368|372,372|376,376 Q:6,9|15,16|19,20|31,39|53,55|127,127|129,132|135,140|144,144|151,165|183,183|185,185|187,205|207,207|215,224|227,228|232,232|236,245|270,272|276,287|291,295|308,320|322,323|328,337|358,358|360,363|369,371|373,375|377,378 ??????EEEE??---TT??TT----------TTHHHHHHH-------------TTT-----------------------------------------------------------------------S?EEEE??TTSTTS???S???---HHHHHHHHHHHHHHH-----------------T?S?EEEEEETHHHHHHHHHHHH?G-------GGEEEEEEES??SS???S???HHHHHHHHHH------------------------HHS???SHHHHHHHHTTT???HHHHH------------HHHTTEETTEESS?HH----HHHHTHHHHH??????-??----------?S?EEEE----?BTT?STT?GG 1CVL|A PF07821.7_Alpha-amyl_C2_seed 33 88 !Q:4,5|8,10|28,45|54,54|59,59|63,67|69,71 Q:0,3|6,7|11,27|46,53|55,58|60,62|68,68|72,87 HHTT??TT-??EEEEEEETTEEEEEETT------------------TEEEEESS?STTG-GGS?----S---SEEEEEEETTEEEEEE 1AMY|A PF07822.6_Toxin_13_seed 2 55 !Q:0,4|23,24|52,54 Q:5,22|25,51 ?????STTTTHHHHHHHHHHHHH??TTGGGTTTHHHHHHHHHHHHHHHTTTT??? 1VIB|A PF07823.6_CPDase_seed 15 348 !Q:0,21|26,35|40,41|43,44|55,55|63,87|97,104|115,115|120,144|148,149|165,168|183,250|256,260|265,266|277,277|280,311|314,314|318,322|329,330|333,333|336,336|339,339|347,347 Q:22,25|36,39|42,42|45,54|56,62|88,96|105,114|116,119|145,147|150,164|169,182|251,255|261,264|267,276|278,279|312,313|315,317|323,328|331,332|334,335|337,338|340,346 ?----------------?????EEEE----------EEEE??T--TTHHHHHHHH-HHHHHHS?------?-----------??????EEEEEEEEE-------?SHHHHHHHHH-HHSS????---------------------EEE??EEEEEEETTEEEEEE????HHHHTTSTTTSSTT----------------------------------------------------------??????????EEEEE?????HHHH--HHHHHHHTTT?SS-------------------------------?TT?EEE---??EEEEEE??TT?TT?TT?EEEEEEE? 1JH7|A PF07824.7_Chaperone_III_seed 4 113 !Q:0,1|12,22|35,35|48,50|72,72|76,76|89,89|112,112 Q:2,11|23,34|36,47|51,71|73,75|77,88|90,111 ??HHHHHHHHTT??-????????EEETTEEEEEEE?SSEEEEEEEEEE???SHHHHHHHHHHHHHSSSEEEE?TTS?EEEEEEEEETTS?HHHHHHHHHHHHHHHHHHHHHH? 1K3S|A PF07825.6_Exc_seed 2 77 !Q:0,0|12,12|15,17|29,29|33,34|37,37|47,47|52,52|54,58|60,76 Q:1,11|13,14|18,28|30,32|35,36|38,46|48,51|53,53|59,59 ?EEEHHHHHHHS-SS???HHHHHHHHHHT?EES??EE?SSSEEEETT?EESS?S?----S????????????????? 1PM6|A PF07826.6_IMP_cyclohyd_seed 6 236 !Q:0,3|11,11|14,15|24,24|27,29|33,33|45,45|48,48|55,55|59,59|89,90|103,103|105,106|110,113|120,120|123,124|136,147|152,153|156,157|165,169|171,171|174,178|182,186|203,204|216,224|226,226|231,231|234,235 Q:4,10|12,13|16,23|25,26|30,32|34,44|46,47|49,54|56,58|60,88|91,102|104,104|107,109|114,119|121,122|125,135|148,151|154,155|158,164|170,170|172,173|179,181|187,202|205,215|225,225|227,230|232,233 ????SEEEEEE?SS?-EEEEEEEE?SS???EEE-EEETTEEEEEE?TT?GGGGGT?TTS?EEEEEEETTEEEEESSTHHHHHHHHHHHT??HHHHHHHHHHHH?S??STT?-??EEEEEE?SS?-EEEEEEETTEE------------EEEE??SS??EEEESSS?---?S?EE?????SSH-----HHHHHHHHTSGGGGSS??EEEEEEEEESS---------S?EEEE-EE?? 1KUU|A PF07827.6_KNTase_C_seed 2 143 !Q:14,16|46,47|72,74|90,91|106,108|132,138|141,142 Q:0,13|17,45|48,71|75,89|92,105|109,131|139,140 ESSSHHHHHHHHHH???HHHHHHHHHHHHHHTHHHHHHHHHHHHHH??GGGHHHHHHHHHHHHHHHHHHHHT???SSSSSHHHHHTTSSS??TTHHHHHHHHHHTB???HHHHHHHHHHHHHHHHHHHHHHT???????SS?? 1KAN|A PF07828.7_PA-IL_seed 2 121 !Q:0,0|9,9|12,12|20,20|23,24|40,40|42,42|45,46|50,51|54,54|56,56|60,60|71,73|76,76|84,86|89,90|98,100|103,103|107,107|118,120 Q:1,8|10,11|13,19|21,22|25,39|41,41|43,44|47,49|52,53|55,55|57,59|61,70|74,75|77,83|87,88|91,97|101,102|104,106|108,117 ?EEEEEETT?TT?EEEEEEE?TT??EEEEEEEEEESSSSS?B?TB??TTS??SS?S?TTS?TTBEEEEETT???EE?TTEEEEE???TT??EEEEEEE???TT?GGG?EEEEEEEEEE??? 3ZYH|A PF07829.6_Toxin_14_seed 2 26 !Q:0,3|10,11|14,14|19,20 Q:4,9|12,13|15,18|21,25 ????SSSSSS??TT?SSSS??HHHHS 1P1P|A PF07830.8_PP2C_C_seed 15 83 !Q:6,6|10,13|35,46|59,60|63,64 Q:0,5|7,9|14,34|47,58|61,62|65,82 EEEEEE?TTS????HHHHHHHHHHHHHHHHHHHHH???--???????HHHHHHHHHHTT-?SS??TTTTTGGGHHHHHHHHHH 3FXM|A PF07831.8_PYNP_C_seed 54 75 !Q:5,5|20,20|25,28|31,31|37,38|41,41|44,44|47,47|58,60 Q:0,4|6,19|21,24|29,30|32,36|39,40|42,43|45,46|48,57|61,74 EEEEE?HHHHHHHHHHHTTS?SSTT????TT?EEEES??TT?EE?TT?EEEEEEESSS?-?HHHHHHHHTTEEEE 1OTP|A PF07832.6_Bse634I_seed 4 323 !Q:0,1|6,6|10,11|17,17|30,32|37,38|59,62|64,65|83,88|99,100|102,102|105,107|111,113|116,125|127,128|134,134|149,150|155,162|169,169|172,172|183,184|188,189|198,200|209,209|211,211|222,222|225,226|253,253|256,260|269,271|281,283|285,285|291,291|295,297|306,306|320,322 Q:2,5|7,9|12,16|18,29|33,36|39,58|63,63|66,82|89,98|101,101|103,104|108,110|114,115|126,126|129,133|135,148|151,154|163,168|170,171|173,182|185,187|190,197|201,208|210,210|212,221|223,224|227,252|254,255|261,268|272,280|284,284|286,290|292,294|298,305|307,319 ??SEEE?SST--TBEEE?HHHHHHHHHHTS?--TTTS-?HHHHHHHHHHHHHHHHHHHT---?B??HHHHHHHHHHHHHHHHH------HHHHHHHHHS??S-EE---EEE???TT----------T??GGGGB?HHHHHHHHHHHHHH--HHTT????????SEEEEE?TT?HHHHHHHTTT??STT??HHHHHHHH---HGGGGGTT?B?TTTEEEEEEE?SS??HHHHHHHHHHHHHHHHHHHHHHHHTT?SS???-?EEEEEESS-??HHHHHHHTS---B?GGGGS?TTS???BSSSEEEE?SSHHHHHHHHHHH??? 3N7B|A PF07833.6_Cu_amine_oxidN1_seed 134 194 !Q:0,5|13,14|18,19|21,26|31,31|41,42|45,50|55,59|63,64|66,81|83,88|94,101|103,109|111,117|122,122|124,125|127,127|129,129|131,134|137,139|141,144|147,148|152,152|162,179|182,188|193,193 Q:6,12|15,17|20,20|27,30|32,40|43,44|51,54|60,62|65,65|82,82|89,93|102,102|110,110|118,121|123,123|126,126|128,128|130,130|135,136|140,140|145,146|149,151|153,161|180,181|189,192 ??????EEHHHHH--HHT--T--?---EEEE-ETTTTEEEE--EE------TTEE-----EEE?-B----------------T-----?SEEEE--------T-------T-------EEEE?S--S?B-E----EE---T----TE--EEE?TTHHHHHHT------------------SS?-----?TTEE? 2WOH|A PF07834.6_RanGAP1_C_seed 3 185 !Q:0,28|37,38|58,59|76,77|104,105|121,122|125,130|132,133|150,150|164,165 Q:29,36|39,57|60,75|78,103|106,120|123,124|131,131|134,149|151,163|166,184 --------------???????????????HHHHHHHS??TTTTGGGGGGGTTTHHHHS??SSHHHHHHHHHHHHTT??SSSHHHHHHHHHHHHHHHHHTSSSSS-?HHHHHHHHHHHTTSS??SS-?????S??HHHHHHHHHHTTSSSS?TTSHHHHHHHHHS??SGGGTTHHHHHHHHHHHHH 2IO3|C PF07835.7_COX4_pro_2_seed 36 52 !Q:0,9|12,12|14,15|40,42|51,51 Q:10,11|13,13|16,39|43,50 ?????-????TT?S??HHHHHHHHHHHHHHHHHHHHHHHH---HHHHHHHH? 1M57|D PF07836.6_DmpG_comm_seed 37 66 !Q:1,2|4,5|16,17|33,34|47,48|51,51 Q:0,0|3,3|6,15|18,32|35,46|49,50|52,65 S??S??HHHHHHHHHT??TTHHHHHHHHHHHHT??HHHHHHHHHHHT??TT?THHHHHHHHHHHHH 4JN6|A PF07837.7_FTCD_N_seed 37 208 !Q:0,0|5,6|10,10|13,13|26,26|31,31|52,52|54,64|82,83|87,89|91,91|93,94|109,110|131,132|140,140|147,147|155,156|166,166|172,184|188,195|200,200|206,206 Q:1,4|7,9|11,12|14,25|27,30|32,51|53,53|65,81|84,86|90,90|92,92|95,108|111,130|133,139|141,146|148,154|157,165|167,171|185,187|196,199|201,205|207,207 ?EEEE??EES?SS?HHHHHHHHHHHH-TSTT?EEEEEEEETTTTEEEEEEEE?H-----------HHHHHHHHHHHHHHHHH??GGG???S-S??SBSEEEEEEEEEES??HHHHHHHHHHHHHHHHHHHT??EEEEETT?SSGGGS?HHHHHTT--HHHHHHHHT-TSGGG-----------??SBS?????---TTTB?EEEEE?S 2PFD|A PF07840.7_FadR_C_seed 29 211 !Q:0,1|6,7|18,19|49,49|54,83|93,94|97,110|131,131|177,177|200,210 Q:2,5|8,17|20,48|50,53|84,92|95,96|111,130|132,176|178,199 ??HHHH??GGGHHHHHHH-?TTTHHHHHHHHHHHHHHHHHHHHHHHHHH?HHHH------------------------------HHHHHGGGT??SS--------------HHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHTTSHHHHHHHHHHHHHHHHHHHHT?GGGHHHHHHHHHHHHHHHHHHH????--????? 1E2X|A PF07848.7_PaaX_seed 13 71 !Q:0,0|10,12|19,19|21,21|34,35|59,63|67,67 Q:1,9|13,18|20,20|22,33|36,58|64,66|68,70 ?HHHHHHHHH---TTTTTS?B?HHHHHHHHTTTT??HHHHHHHHHHHHHTTSEEEETTE-----EEE?HHH 3KFW|X PF07850.9_Renin_r_seed 8 114 !Q:7,8|13,14|35,43|49,51|53,54|77,77|87,94|96,97|104,113 Q:0,6|9,12|15,34|44,48|52,52|55,76|78,86|95,95|98,103 HHHHHHS??SEES--BHHHHHHHTTSHHHHHHHHH---------HHHEE???S--TTHHHHHHHHHHHHHHHHHTSS?HHHHHHHHH--------S??TTSGGG?????????? 3LBS|A PF07856.7_Orai-1_seed 15 287 !Q:0,5|17,34|59,74|102,139|147,150|162,164|185,248 Q:6,16|35,58|75,101|140,146|151,161|165,184|249,286 ??????HHHHHHHHHHH------------------HHHHHHHHHHHHHHHHHHHHHHHH????????----????HHHHHHHHHHHHHHHHHHHHHHHHTTT??------------------???????????--?????HHHHHHH----HHHHHHHHHHH---HHHHHHHHHHHHHHHHHTTT---------------------------------------------------------------?HHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHTHHHHHH 4HKR|A PF07858.7_LEH_seed 7 127 !Q:17,17|30,30|42,42|54,56|60,60|87,88|115,116 Q:0,16|18,29|31,41|43,53|57,59|61,86|89,114|117,126 HHHHHHHHHHHHHHHHT?HHHHHHHEEEEE-EEEETTTEEEE?HHHHHHHHHTT---TTT?EEEEEEEEEEEETTEEEEEEEEEEEE--TTEEEEEEEEEEEEEETTEEEEEEEE??HHHHHHHHHH 3EBT|A PF07859.8_Abhydrolase_3_seed 130 350 !Q:4,5|10,12|14,15|17,17|21,22|34,35|42,47|49,49|53,53|71,71|73,111|113,113|117,118|120,123|126,127|145,146|153,158|160,174|183,201|204,206|210,212|216,216|221,221|224,230|236,236|240,240|243,245|247,249|252,253|259,259|262,266|269,269|272,275|278,286|289,301|310,310|325,325|327,328|331,332|337,337|345,345 Q:0,3|6,9|13,13|16,16|18,20|23,33|36,41|48,48|50,52|54,70|72,72|112,112|114,116|119,119|124,125|128,144|147,152|159,159|175,182|202,203|207,209|213,215|217,220|222,223|231,235|237,239|241,242|246,246|250,251|254,258|260,261|267,268|270,271|276,277|287,288|302,309|311,324|326,326|329,330|333,336|338,344|346,349 EEEE??STTT---S??T-TTT--HHHHHHHHHHH??EEEEEE??---?T-TTS?TTHHHHHHHHHHHHHHH?H---------------------------------------H-HHT--B?---TT-?EEEEEETHHHHHHHHHH--HHHHHT------T-???-----------EEEEEEES?---????-----------SS???HHH---HHT?SGGG?TT----?--HHHHH-HHH-HH---H?--SS--GGGGG-ST-----TT?GG----GS----?---?TT--??-?-------EEEEEEEE?TTHHHHHHHHHHHH-H--TT??EEEE-EEEEEET-TGGG 2VJB|A PF07866.6_DUF1653_seed 54 84 !Q:0,0|8,16|18,19|35,35|45,46|49,49|61,61|66,66|73,78 Q:1,7|17,17|20,34|36,44|47,48|50,60|62,65|67,72|79,83 ?EEEEETT---------S-?EEEEEEEEEETTTTE-EEEEEEESS??SS?SEEEEEHHHHT?EEEE-TTEEEE------SEEEE 3BE3|A PF07873.6_YabP_seed 73 68 !Q:0,8 Q:9,67 -----????EEEEESSEEEEEEEETTEEEEEETTEEEEEEEEEEEEEEEETTTTEEEEEEEEEEEEES 3IPF|A PF07876.7_Dabb_seed 51 134 !Q:9,9|12,13|18,19|23,26|34,40|44,44|47,48|52,53|57,59|63,67|71,73|82,82|87,87|93,93|96,105|112,112|121,124|132,133 Q:0,8|10,11|14,17|20,22|27,33|41,43|45,46|49,51|54,56|60,62|68,70|74,81|83,86|88,92|94,95|106,111|113,120|125,131 EEEEEEEEE?TT??HHHH--HHH----HHHHHTH-------HHH?TT??EEE--EEE???SSS----?STT-??EEEEEEES?HHHH-HHHHH-SH----------HHHHHH-HHHHHTEE----EEEEEEE?? 1TR0|A PF07880.6_T4_gp9_10_seed 14 329 !Q:0,4|7,7|37,37|40,40|47,48|50,50|53,53|55,59|62,64|66,68|71,81|85,85|87,87|89,89|92,92|96,98|100,102|105,106|112,123|126,126|132,132|135,138|140,142|145,145|149,150|159,160|164,165|169,170|182,182|186,190|195,198|206,209|211,211|217,219|226,226|232,232|236,236|249,254|258,258|270,270|274,276|285,285|292,294|300,300|302,302|309,309|320,321 Q:5,6|8,36|38,39|41,46|49,49|51,52|54,54|60,61|65,65|69,70|82,84|86,86|88,88|90,91|93,95|99,99|103,104|107,111|124,125|127,131|133,134|139,139|143,144|146,148|151,158|161,163|166,168|171,181|183,185|191,194|199,205|210,210|212,216|220,225|227,231|233,235|237,248|255,257|259,269|271,273|277,284|286,291|295,299|301,301|303,308|310,319|322,328 ?????TT?SSSSSHHHHHHHHHHHHHHHHHHHHTTSS?GG-GGGSSS--S?ST-T?????TT???B???TT-----------GGG-S?B?TT?EEE???S---SS?-EEEEE??-----?---?TT?EEEEE?TT????S---SS?EEE--EESSEETT-?SSS--EEE??TTEEEEEEEEE?SSS??---EEEE----EEEESSS????S?EEEEE-??TTSEEE-EEEEE-TTT?SEEEEEEEEEET------TSS?EEEEEEEEEEE-TTT---TEEEEEEE-EEEESS--?SSSSS?S?EEEEEE-ETTEEEEEEE?-SSSSEEE 1TJA|C PF07881.7_Fucose_iso_N1_seed 17 175 !Q:0,0|2,3|11,14|18,19|43,43|45,45|49,49|51,52|56,56|59,59|61,61|88,90|96,98|102,102|108,108|110,110|112,113|133,135|140,140|143,145|148,152 Q:1,1|4,10|15,17|20,42|44,44|46,48|50,50|53,55|57,58|60,60|62,87|91,95|99,101|103,107|109,109|111,111|114,132|136,139|141,142|146,147|153,174 ?S??EEEEEEB????TTT--HHHHHHHHHHHHHHHHHHHHHHH?B?TTS?B??EEE?SS?B?SHHHHHHHHHHHHTTTEEEEEEEESS???HHHHS???SSS?EEEEE?B?S--SSBHHHHHHHHHHHHHHTT???EEEE?SS???TT?????HHHHHHHHHHHHHHHHHHHHTT 3A9T|A PF07882.7_Fucose_iso_N2_seed 21 189 !Q:0,0|7,9|12,12|17,18|27,28|34,34|46,46|48,48|63,66|68,71|73,75|79,81|86,89|109,110|118,118|124,126|133,134|143,144|162,166|172,172|187,187 Q:1,6|10,11|13,16|19,26|29,33|35,45|47,47|49,62|67,67|72,72|76,78|82,85|90,108|111,117|119,123|127,132|135,142|145,161|167,171|173,186|188,188 ?EEEEES???TT?GGGS??HHHHHHTT??EEEEE?THHHHHHHHTT?S?HHHHHHHHHHHHHH??--B????S--?GGG???HHHH----HHHHHHHHHHHHHHHHHHH??HHHHHTT?HHHHH???EEEEEE??TTTTTTTS??SHHHHHHHHSSEETTEE?????EEETT?HHHHHHHHHHHHHH?S 3A9T|A PF07883.6_Cupin_2_seed 156 99 !Q:5,5|8,9|13,15|19,19|21,21|24,27|35,35|37,37|39,39|45,47|50,52|56,57|60,60|65,65|67,67|69,70|72,72|76,76|78,83|87,88|96,96 Q:0,4|6,7|10,12|16,18|20,20|22,23|28,34|36,36|38,38|40,44|48,49|53,55|58,59|61,64|66,66|68,68|71,71|73,75|77,77|84,86|89,95|97,98 EEEEE?TT?-EEE---EEE-E-SS?---EEEEEEE?S-S?EEEET---TE---EEE??TT?EEEE?T-T--S?EEE-E?----?SSS-?EEEEEEE?HH 2CAU|A PF07884.9_VKOR_seed 38 174 !Q:0,0|25,33|35,50|61,62|65,77|93,93|98,102|104,112|114,114|120,120|143,144|148,152|173,173 Q:1,24|34,34|51,60|63,64|78,92|94,97|103,103|113,113|115,119|121,142|145,147|153,172 ?SHHHHHHHHHHHHHHHHHHHHHHH???-----?S?????-----????--SGGGSSSSEE--TT-------------EEHHHHHHHHHHHHH-HHHH?????T---------T?STTHH-HHHHHHHHHHHHHHHHHHHHHH--HTS?-???HHHHHHHHHHHHHHHHHHSS? 3KP9|A PF07885.11_Ion_trans_2_seed 123 113 !Q:16,32|35,38|42,42|54,57|59,59|61,67|71,75|77,83|88,88 Q:0,15|33,34|39,41|43,53|58,58|60,60|68,70|76,76|84,87|89,112 HHHHHHHHHHHHHHHH-----------------HS-???HHH-HHHHHHHHHTT????S-S---???-SHH-----H-------HHHH-HHHHHHHHHHHHHHHHHHHHHTHH 2H8P|D PF07892.6_DUF1667_seed 35 83 !Q:0,14|24,24|29,29|41,41|55,55|58,62|76,76|81,81 Q:15,23|25,28|30,40|42,54|56,57|63,75|77,80|82,82 --------------?EEEEEEEEE?SSSS?SEEEEEEEEEE?HHHHHHHHHHHTT?EE?????SSEEEEESTTSSS?EEEE?S 2JOV|A PF07896.7_DUF1674_seed 75 88 !Q:4,5|11,53|55,67|69,81|85,87 Q:0,3|6,10|54,54|68,68|82,84 HHHT??TTTTT??--------------------------------??-----??S?---?-???????S?------??????STT??? 2K5K|A PF07908.7_D-aminoacyl_C_seed 150 69 !Q:3,4|6,9|12,13|17,19|34,34|36,42|46,49|51,51|53,63|65,68 Q:0,2|5,5|10,11|14,16|20,33|35,35|43,45|50,50|52,52|64,64 TTT-?B????SS--STT???BSEEEEEETTEEEE-E-------TTE----E?S------?????B???? 1V51|A PF07910.8_Peptidase_C78_seed 38 338 !Q:0,0|5,6|8,9|11,13|20,21|25,25|41,47|51,56|58,64|77,77|80,82|84,91|96,101|113,113|115,117|124,172|177,179|192,193|196,219|225,226|228,251|263,269|273,274|281,281|284,285|287,288|290,290|303,317|319,319|323,324|326,326|328,330|333,333 Q:1,4|7,7|10,10|14,19|22,24|26,40|48,50|57,57|65,76|78,79|83,83|92,95|102,112|114,114|118,123|173,176|180,191|194,195|220,224|227,227|252,262|270,272|275,280|282,283|286,286|289,289|291,302|318,318|320,322|325,325|327,327|331,332|334,337 ?EEEE??S??B???SSBTTB??TTT?HHHHHHHHHHHHHHH-------TTS----??S---????HHHHHHHHHHHT-SS--?G--------GGTT??????HHHHHHHHHHH-H???EEEEEE?-----------------------------------------------?GGGG---GGGHHHHHHHHT--TT-?--------------------??EEEEE--T------------------------TEEEEEEEEEE?------TTT??EEEEEE?TT??S?-S?HHHHHHTTSEEE---------------E?TTS--S?S---SS?EEEE 2Z84|A PF07912.8_ERp29_N_seed 3 128 !Q:0,2|5,5|8,9|29,29|32,33|51,51|61,63|67,67|78,79|83,84|91,91|100,102|106,108|122,126 Q:3,4|6,7|10,28|30,31|34,50|52,60|64,66|68,77|80,82|85,90|92,99|103,105|109,121|127,127 ???TT?EE??TTTHHHHHTTSSEEEEEEE?SS??SHHHHHHHHHHHHHHHH?SSEEEEEEE???SSS?TTHHHHHHTT??GGG??EEEEES-SSSSSEEE?-?TTS???HHHHHHHHHHHSS?????T 2C0G|A PF07915.8_PRKCSH_seed 104 175 !Q:0,2|5,7|10,10|13,19|29,33|40,40|42,66|72,72|74,75|82,111|119,147|150,162|169,170|172,172|174,174 Q:3,4|8,9|11,12|20,28|34,39|41,41|67,71|73,73|76,81|112,118|148,149|163,168|171,171|173,173 ???EE---EE-ET-------TEEEEEETT-----TEEEEE?E-------------------------ETTEE?S??EEEEEE------------------------------EEEEEEE?????----------------????????EE-------------EEEEEE??S-B? 3AIH|A PF07920.6_DUF1684_seed 59 206 !Q:1,1|4,5|7,13|21,23|28,37|40,62|68,68|71,72|89,92|95,95|105,109|113,114|116,117|124,124|130,131|134,134|137,137|143,144|147,149|152,159|161,165|173,173|175,176|181,181|185,190|195,195|198,201|203,205 Q:0,0|2,3|6,6|14,20|24,27|38,39|63,67|69,70|73,88|93,94|96,104|110,112|115,115|118,123|125,129|132,133|135,136|138,142|145,146|150,151|160,160|166,172|174,174|177,180|182,184|191,194|196,197|202,202 H-HH??S???????GGGEEEE---EEEE---------?SS?---------------------?EEEEE?SS--SSEEEEEEEEEEEEEE----TT-EEEEEEEEE-----SSS??S??EEEEEB?SSBTT--TB?TT?EEEEE??SS???TT-------?E-----EEEEGGG?B??HHHH?TTS??????GGGB?SS????S??? 4FJ4|A PF07921.7_Fibritin_C_seed 9 127 !Q:0,0|10,10|16,17|35,35|37,37|40,40|42,42|48,48|88,102|105,112 Q:1,9|11,15|18,34|36,36|38,39|41,41|43,47|49,87|103,104|113,126 ?HHHHHHHHH-HHHHH??SSSSHHHHHHHHHHHHH?S?TT?S-SHHHH?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?-------???????SS------??EEEETTEEEEGGGT 2KBL|A PF07922.6_Glyco_transf_52_seed 16 326 !Q:2,2|11,12|35,36|39,41|43,43|46,48|60,66|90,90|96,97|104,104|117,128|151,153|159,159|162,164|166,167|170,170|179,189|193,198|200,200|207,211|213,230|234,237|250,255|259,260|263,264|266,267|269,269|274,276|279,279|291,291|294,294|303,303|315,315 Q:0,1|3,10|13,34|37,38|42,42|44,45|49,59|67,89|91,95|98,103|105,116|129,150|154,158|160,161|165,165|168,169|171,178|190,192|199,199|201,206|212,212|231,233|238,249|256,258|261,262|265,265|268,268|270,273|277,278|280,290|292,293|295,302|304,314|316,325 TS?EEEEEEES??SHHHHHHHHHHHTTSSEEEEEE??TT???S?SS???HHHHHHHHTTS?----??SEEEEETTHHHHTHHHHHTSTTS-EEEEE??SGGGGS?GGGGGSGGGTSS------------SSHHHHHHHHHHHHHHHHHHSS???EEEES?TT---S??TT?SSSSEEEE?????-----?TTS??????S?EEEEEE??---S-----------------?GGG----HHHHHHHHHHTT??----EEE??TT??S??S-SSEE???SS?HHHHHHHHHHH?TT?EEEEEESS?THHHHHTTSTT-EEEEEEEETT 2YK6|A PF07924.6_NuiA_seed 6 134 !Q:0,2|17,18|26,27|35,36|39,40|50,51|55,55|60,60|70,72|75,76|118,118|122,122|132,133 Q:3,16|19,25|28,34|37,38|41,49|52,54|56,59|61,69|73,74|77,117|119,121|123,131 ???HHHHHHHHHHHHTT??EESSSEE??EEEEESS??SS??HHHHHHHHT??TTS?EEEE?HHHHTHHHH???TT??HHHHHHHHHHHHHHHHHHHHSEEEEEEEESSSEEEEEEEEE?TTS?EEEEEEEEE?? 2O3B|B PF07925.6_RdRP_5_seed 3 1274 !Q:0,1|20,22|37,37|49,51|55,59|64,67|75,75|78,79|83,84|87,87|90,91|93,98|105,105|108,108|115,115|125,125|127,127|146,146|150,150|165,165|167,167|176,180|184,184|201,201|203,205|210,210|213,213|218,219|221,223|225,226|247,249|268,268|288,289|292,294|304,304|310,310|320,321|326,327|329,331|344,344|358,359|377,379|381,384|395,399|402,404|419,419|422,423|443,443|448,448|460,460|464,466|479,484|487,488|490,490|505,505|516,516|519,519|533,533|535,536|560,564|571,571|583,583|598,598|621,622|627,628|634,635|639,640|646,646|662,662|669,669|675,675|682,685|715,717|727,728|745,746|752,753|773,773|779,779|782,782|797,798|803,803|807,810|814,817|837,838|857,858|871,872|881,883|886,886|889,890|893,893|895,895|898,899|925,925|938,938|958,958|961,971|1004,1007|1015,1018|1035,1037|1055,1056|1058,1060|1077,1079|1082,1082|1085,1086|1106,1106|1108,1109|1111,1111|1120,1120|1122,1122|1124,1126|1130,1130|1146,1147|1160,1161|1175,1178|1188,1191|1198,1198|1209,1209|1211,1211|1215,1216|1220,1222|1225,1225|1247,1247 Q:2,19|23,36|38,48|52,54|60,63|68,74|76,77|80,82|85,86|88,89|92,92|99,104|106,107|109,114|116,124|126,126|128,145|147,149|151,164|166,166|168,175|181,183|185,200|202,202|206,209|211,212|214,217|220,220|224,224|227,246|250,267|269,287|290,291|295,303|305,309|311,319|322,325|328,328|332,343|345,357|360,376|380,380|385,394|400,401|405,418|420,421|424,442|444,447|449,459|461,463|467,478|485,486|489,489|491,504|506,515|517,518|520,532|534,534|537,559|565,570|572,582|584,597|599,620|623,626|629,633|636,638|641,645|647,661|663,668|670,674|676,681|686,714|718,726|729,744|747,751|754,772|774,778|780,781|783,796|799,802|804,806|811,813|818,836|839,856|859,870|873,880|884,885|887,888|891,892|894,894|896,897|900,924|926,937|939,957|959,960|972,1003|1008,1014|1019,1034|1038,1054|1057,1057|1061,1076|1080,1081|1083,1084|1087,1105|1107,1107|1110,1110|1112,1119|1121,1121|1123,1123|1127,1129|1131,1145|1148,1159|1162,1174|1179,1187|1192,1197|1199,1208|1210,1210|1212,1214|1217,1219|1223,1224|1226,1246|1248,1273 ??THHHHHHHHHHHHTTTSS???HHHHHHHHHHHHHS?HHHHHHHHHTS???GGG?????GGGT????GGGGEEE?TT??EEE??SS?TT??S??????GGGEEE?SS?TTEEEE?HHHHHHHHT-T?HHHHHHHHHHHHHHHHHT?BSS?HHHHHHHHHHHHTT?S?EETTTTEE?????GGG?HHHHHHHHHHHHHHTT?S???SEEE?SS?EEEE??T---T??TTHHHHHHHHHHHHHHHHHS???HHHHHHHHHHHHHHHHSS?HHHHHHHHTTHHHHTTGGG??SS??-EEEEEEEEE?SSGGG?BEEEEEEEE??GGGS??S???HHHHHHHHHHTT?HHHHHHHHHHHHT??EESHHHHHHHHHHHTSS???B????HHHHHHHHSS?????SS???GGGEEEEETTEEEE?TT??STHHHHHHHHHHHHHHHHH?GGGG?HHHHHHHHHTT?SSS???HHHHHHHHHTTT??????TT??S?SSSHHHHHHHHTTS?HHHHGGGGGS?EE?EEEEEBTEEEEEE?B??HHHHHHHHHHHHHHHHHHHHTSB?????SSGGGS?HHHHHHHHSTT?EEEEEEEETHHHHS?TTTHHHHHHHHHHHHTHHHHTT??BTTB??EEEEE??SSS??EEEEE?HHHHHHHHHHHHHHH?EEEEEE?SSSTT?EEEEEE????SBSSSHHHHHHHHHHHHHHHHHHTHHHHT???HHHHHHHHT??TTTTEEEETTEEEEEE??BTTBS??HHHHHHHHHHHHHHHHTTT?EEEEE?SS?EEETTEEEETTEEE??GGGS?SSB????SSS????TTHHHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHHSEE--EEEETTEEEEEE??HHHHHHTT???SS?TT??TT?B?TT??SHHHHHHHHHHHHHHHHHHHHHHTT?EEEEEETTTEEE?HHHHHHHTTHHHHHHHHTS?SS???????????HHHHHHHHHHHHHTTSHHHHHHHHHHHHHHHH----HTBTTBS????GGGHHHHHHHHHHHTS???HHHHHHHHHHHHHHHHS??S???HHHHHHTTEEEEEEEE???SS?TT??SBTTBSTTSHHHHHHHHHH?B??B?HHHHHGGG?S?S???TTS?HHHHHHHHHHHHHTT??HHHHHHHHHTTT??HHHHHHHHHHHHH????HHHHHGGGT????GGGTTB?HHHHHHHSEE?S?TTS??TTT???TT?TTHHHHHHHHHHHHHHHBSSS?EEEEEEEETTHHHHHHHHHHHHHHHS 2CSE|1 PF07927.7_YcfA_seed 255 91 !Q:9,9|12,12|14,24|28,29|32,32|34,34|42,42|46,46|48,57|62,64|66,68|72,74|80,82|85,85|88,88 Q:0,8|10,11|13,13|25,27|30,31|33,33|35,41|43,45|47,47|58,61|65,65|69,71|75,79|83,84|86,87|89,90 HHHHHHHHH-HT-T--------?--EEE--EE-E-TTEEEEE?TTS?E----------EEEE--?S---SSS-??HHHHH---HH-HH-HT 1WHZ|A PF07929.6_PRiA4_ORF3_seed 18 227 !Q:0,1|13,13|16,16|27,27|42,45|47,47|54,55|59,59|61,82|89,99|101,102|108,108|114,114|116,117|121,121|128,128|145,146|149,150|154,154|161,165|169,169|183,183|188,194|204,204|207,216|219,221|225,226 Q:2,12|14,15|17,26|28,41|46,46|48,53|56,58|60,60|83,88|100,100|103,107|109,113|115,115|118,120|122,127|129,144|147,148|151,153|155,160|166,168|170,182|184,187|195,203|205,206|217,218|222,224 ??EEEEEEEEETT?SS?EEEEEEEETT?BHHHHHHHHHHHTT????S?EEEEEE-?TTT?S----------------------EEEEES???????????E--EETTT?BHHHH?B--TTB?EEEEEE?TTTTEEEEEEEEEEEE??TT??SSE-EEEEES?-???TTS?HHHHHHHHHHHHT?TTST-------THHHHHHHH?TT--------??TT???GGG?? 2I1S|A PF07930.7_DAP_B_seed 2 88 !Q:0,9|13,13|18,18|22,23|30,30|39,39|43,43|56,56|59,59|84,85|87,87 Q:10,12|14,17|19,21|24,29|31,38|40,42|44,55|57,58|60,83|86,86 ??????????GGG?EEEE?TTT??EEEEEE?STTEEEEE?SSS?EEEEEEETTEEE?SS?EEEEETTEEEEEEGGGTEEEEEEE??S? 1EI5|A PF07931.7_CPT_seed 7 222 !Q:0,1|8,8|27,27|31,32|40,40|42,42|48,62|67,67|77,85|107,107|113,116|118,119|125,125|137,138|146,147|150,150|161,166|171,183|196,198|208,208|220,221 Q:2,7|9,26|28,30|33,39|41,41|43,47|63,66|68,76|86,106|108,112|117,117|120,124|126,136|139,145|148,149|151,160|167,170|184,195|199,207|209,219 ??EEEEEE?TTSSHHHHHHHHHHHSSS?EEE??HHHHHHH-S?GGGGT---------------STTS?EEETTTEEE?-------?HHHHHHHHHHHHHHHHHHHTT?EEEEE----E??TTTHH-HHHHHHHHHTT??EEEEEEE??HH-HHHHHHHHHT?-----SSTT-------------HHHHHTTGGGTT???SEEEETTTS?HHHHHHHHHTT?? 1GRQ|A PF07932.7_DAP_C_seed 5 97 !Q:0,1|5,5|37,39|42,42|55,57|62,63|73,73|77,77|96,97 Q:2,4|6,36|40,41|43,54|58,61|64,72|74,76|78,95 ??STT?EEEEETTTTEEEEEEEETTEEEEEEEETTEE???EE?EEEETTEEEEEE???SSSS??EEEEEEEEE?TTS?EEEEEEEETTEEEEEEEE?- 1EI5|A PF07933.9_DUF1681_seed 23 278 !Q:0,1|3,5|7,9|17,20|22,23|27,27|29,30|35,37|39,46|49,49|58,100|105,106|112,112|115,116|119,119|121,146|151,151|154,158|162,162|165,166|168,168|177,177|180,183|192,192|194,194|211,224|227,277 Q:2,2|6,6|10,16|21,21|24,26|28,28|31,34|38,38|47,48|50,57|101,104|107,111|113,114|117,118|120,120|147,150|152,153|159,161|163,164|167,167|169,176|178,179|184,191|193,193|195,210|225,226 ??S???B?-?SSEEEEE??--S??SSS-S??HHHH-??S--------SS?EEEEEEEE-----------------------------------------??SSSE--EEEEE?SS??SS?E--------------------------EEEE?SS?-???EEE?TT??S?EEEEEEET-TT----EEEEEEEE?S?HHHHHHHHHHHHHHHS?-------------SS??------------------------------------------------- 1TQZ|A PF07934.7_OGG_N_seed 95 301 !Q:5,6|8,11|17,18|23,23|26,27|30,36|38,39|43,51|57,64|66,66|68,72|79,79|81,84|87,107|115,177|194,212|218,218|222,226|229,237|240,249|253,277|283,285|288,295 Q:0,4|7,7|12,16|19,22|24,25|28,29|37,37|40,42|52,56|65,65|67,67|73,78|80,80|85,86|108,114|178,193|213,217|219,221|227,228|238,239|250,252|278,282|286,287|296,300 EEEES??S--??HHHHH--TSSS?SS--EE-------E?-TTS------?--EEEEE--------T-T-----EEEEEE-E----ET---------------------TEEEEET??-------------------------------------------------------------HHHHHHTHHHHTTTTS--?----------------HHHHH-HHH-----TT---------SH----------HHH-------------------------HHHTT?--TT???-????HHHHH 4EJY|A PF07936.7_Defensin_4_seed 10 37 !Q:0,4|7,8|10,11|15,15|17,18|21,22|26,29 Q:5,6|9,9|12,14|16,16|19,20|23,25|30,36 ?????SS??S??EEE?S-?SS??TTT????EEEETTE 1WXN|A PF07938.7_Fungal_lectin_seed 3 333 !Q:4,4|7,8|14,17|39,40|47,47|56,57|60,62|66,68|81,81|94,94|99,99|102,102|108,109|111,112|115,116|122,122|125,125|128,131|138,138|141,143|155,155|165,166|169,170|177,178|181,181|184,184|186,186|193,193|197,197|210,210|212,213|219,221|224,225|246,246|255,258|275,276|279,280|287,288|293,294|301,303|308,309|311,312|325,326|329,329|332,332 Q:0,3|5,6|9,13|18,38|41,46|48,55|58,59|63,65|69,80|82,93|95,98|100,101|103,107|110,110|113,114|117,121|123,124|126,127|132,137|139,140|144,154|156,164|167,168|171,176|179,180|182,183|185,185|187,192|194,196|198,209|211,211|214,218|222,223|226,245|247,254|259,274|277,278|281,286|289,292|295,300|304,307|310,310|313,324|327,328|330,331 GGGB?TT??EEEEE----ETTEEEEEEEBTTSEEEEEEE--SSSEEE?SGGGEEEE??TT???EEE---EETTTEEEEEEE?TTSBEEEEEEET-TTEE-EE?GGGGG??B??TT??EEEEE?TT?SS--??EEEEEE?TT---SEEEEEEESSS?EEEEEEEEE??TT??EEEEEE??TT?SS?E-EEEEEE?TTS?EEEEEEETTTEE?S??EEEES???TT??EEEEEEEEETTEEEEEEEEE?TTSEEEEE----EEETTTEEEEEEEEEE??TT??EEEEEE??GGGT??EEEEEE???TTTT??E--EEEEETTTEEEE??SS?TT? 4AGI|A PF07940.8_Hepar_II_III_seed 158 280 !Q:9,9|12,12|16,16|18,18|24,28|33,41|44,45|47,47|56,56|63,65|67,78|82,93|100,100|103,103|115,115|118,123|126,145|149,170|175,176|188,191|198,198|206,229|244,252|261,277 Q:0,8|10,11|13,15|17,17|19,23|29,32|42,43|46,46|48,55|57,62|66,66|79,81|94,99|101,102|104,114|116,117|124,125|146,148|171,174|177,187|192,197|199,205|230,243|253,260|278,279 TTTEEEEEE?TT?TTT?E-EEEEE---??TTTT--------?TT??S?TTEEEEEE-TTEEEE???S???--------?TTS------------HHHHHT-TT-SGGGSSSEEET-TB???--?SS?-------------------HHH----------------------HHHS??EEEEEEEETTE----EEEEEE?HHHHHTT?-----------------------TTEEEEEEEEEEET---------TTEEEEEE-----------------EE 4FNV|A PF07941.6_K_channel_TID_seed 2 79 !Q:0,9|14,18|39,41|48,48|51,64|66,78 Q:10,13|19,38|42,47|49,50|65,65 ??????????TTTS?????SGGGGHHHHHHGGGTTSSTT???HHHHSS?SS??????-???????S---?????????? 1ZTO|A PF07943.8_PBP5_C_seed 74 136 !Q:4,4|7,7|10,11|13,15|27,31|37,37|40,45|49,49|51,55|58,58|69,69|76,81|83,83|85,85|88,88|94,99|102,102|112,123|125,125|130,130|132,132|134,134 Q:0,3|5,6|8,9|12,12|16,26|32,36|38,39|46,48|50,50|56,57|59,68|70,75|82,82|84,84|86,87|89,93|100,101|103,111|124,124|126,129|131,131|133,133|135,135 EEEE?SS?TT??S---EEEEEESBSSS-----EEEEE?TT??---?EEE-E-----TT?GGGEEEEEEE-SSSSEE------S?B?TT?EEEEE------EE-EETTEEEEE------------E-EEEE?S?B?B 1Z6F|A PF07945.6_Toxin_16_seed 2 36 !Q:0,4|9,10|13,16|24,25|29,29|35,35 Q:5,8|11,12|17,23|26,28|30,34 ?????TTSB??SS????TTEEEEE-?TTS?EEEEE? 1DL0|A PF07949.7_YbbR_seed 190 129 !Q:0,1|3,6|13,15|19,19|27,30|32,36|41,41|43,43|47,52|55,55|57,57|61,63|66,69|71,71|74,75|77,83|85,85|89,93|96,100|107,118|120,120|124,125 Q:2,2|7,12|16,18|20,26|31,31|37,40|42,42|44,46|53,54|56,56|58,60|64,65|70,70|72,73|76,76|84,84|86,88|94,95|101,106|119,119|121,123|126,128 ??E----EEEEES???TTE-EEEEEEE----S???-?EEEE?H-HHH------HH?S?EEE---EE----E?TT??S------?E-EEE-----EE?--??TTEEEE------------S?EEE--EEE 2KXY|A PF07951.7_Toxin_R_bind_C_seed 10 246 !Q:5,6|9,9|11,11|17,17|21,21|30,30|38,38|44,45|50,57|59,60|62,63|65,67|70,72|74,74|77,77|79,79|86,96|98,98|102,102|109,109|118,124|127,127|129,131|134,134|137,138|140,143|145,147|152,156|161,163|166,167|169,169|180,180|182,182|187,188|190,191|194,208|212,212|223,223|226,227|230,230|233,233|238,239|244,246 Q:0,4|7,8|10,10|12,16|18,20|22,29|31,37|39,43|46,49|58,58|61,61|64,64|68,69|73,73|75,76|78,78|80,85|97,97|99,101|103,108|110,117|125,126|128,128|132,133|135,136|139,139|144,144|148,151|157,160|164,165|168,168|170,179|181,181|183,186|189,189|192,193|209,211|213,222|224,225|228,229|231,232|234,237|240,243 HHHHH??SB?B?TTSSB?BTT?EEEEEESS?TTEEEEE?SSSSS--EEEE--------E??B??S?-?TT???B?SS?S?EEEEEE??-????????B?BTT?EEEEEE-EETTEEEE-?-----BB?S???SS-EE??B-???S???TTSB?---?EEEE???SS??S?BEEEEESSSS?S?EEEE--E??EE--??????????-??EES?EESHHHHHHT?SS??TT?SS?EEEE??BTTB??- 1S0F|A PF07952.7_Toxin_trans_seed 8 329 !Q:0,0|10,11|14,17|22,22|29,29|35,36|38,38|48,50|71,72|74,75|81,83|85,85|94,94|96,96|111,111|116,116|118,130|133,135|138,138|140,141|209,209|214,215|218,219|254,254|289,289|306,317|321,321|324,324|326,326 Q:1,9|12,13|18,21|23,28|30,34|37,37|39,47|51,70|73,73|76,80|84,84|86,93|95,95|97,110|112,115|117,117|131,132|136,137|139,139|142,208|210,213|216,217|220,253|255,288|290,305|318,320|322,323|325,325|327,328 ?HHHHHHHTS??SS????EEES?HHHHHH?TTEEE??S?HHHHTTTSS???GGGHHHHHHHHTTHHHHHHT??B??SSSTT???B?TTHHHHHT?S?HHHHHSHHHHHHHH?GGGT?S?????????????EE???SS?S??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHTTTGGGSS?HHHH??SS??TTSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHTHHHHHHHHHHHHHHHHHHHTTTTSG-GGHHHHHHHHHHHTTS????----????SSS?SS?S?ST 1S0F|A PF07953.7_Toxin_R_bind_N_seed 13 206 !Q:6,6|10,11|18,19|22,22|24,24|26,26|44,45|49,52|55,56|65,69|72,72|75,76|79,80|92,95|113,113|117,117|125,126|132,132|136,136|147,147|153,153|167,167|170,176|186,187|189,189|191,191|204,205 Q:0,5|7,9|12,17|20,21|23,23|25,25|27,43|46,48|53,54|57,64|70,71|73,74|77,78|81,91|96,112|114,116|118,124|127,131|133,135|137,146|148,152|154,166|168,169|177,185|188,188|190,190|192,203 SSSEEE?SSS??EEEEEE??EE?S-S?TTEEEEESSSSEEEEEE??TTT????SS??EEEEEEEE?????SG-GG--TT??EEEEEEEETTT----EEEEEEEETTEEEEEEE?TTS?EEEEEEE??SBSSS?SST-TSEEEEEEEE?TTSEE-EEEETTEEEEEEE?TT???????SEEEEEEES??S-S?EEEEEEEEEESS?? 1S0F|A PF07955.6_DUF1687_seed 9 199 !Q:0,2|5,6|9,12|19,21|38,40|42,54|60,60|63,66|81,90|100,135|153,153|163,171|179,180|185,190 Q:3,4|7,8|13,18|22,37|41,41|55,59|61,62|67,80|91,99|136,152|154,162|172,178|181,184|191,198 ???SS??SS??-?EEEEEE???SSSTTIIIIITTTTSS???S-------------SEEEE-EE????HHHHHHHHHSSSSH----------HHHHHHHSS------------------------------------SHHHHTTTTTIIIIISS?THHHHTTSS????---??EEEESSS??EEES------SHHHHHHH 1WPI|A PF07963.7_N_methyl_seed 72 20 !Q:0,3 Q:4,19 --??HHHHHHHHHHHHHHHH 1OQW|A PF07965.7_Integrin_B_tail_seed 58 107 !Q:1,1|15,15|23,27|32,33|36,36|38,39|45,48|50,50|52,53|55,59|65,65|68,68|70,70|77,81|85,87|89,90|98,99|101,106 Q:0,0|2,14|16,22|28,31|34,35|37,37|40,44|49,49|51,51|54,54|60,64|66,67|69,69|71,76|82,84|88,88|91,97|100,100 H-HHHHHHHHHHHHS?SHHHHTT----?HHHH??SE-E--EEESS????S-S??E-----EEEEE?TT-S?EEEEEE?---?SSS---S??EEEEESS?-B?????? 4G1E|B PF07966.7_A1_Propeptide_seed 85 29 !Q:0,0|8,10|20,20|28,28 Q:1,7|11,19|21,27 ?EEEEEEE???HHHHHHHTT?HHHHHTT? 1AVF|P PF07968.7_Leukocidin_seed 19 298 !Q:12,12|24,24|28,34|37,44|53,62|70,70|75,75|83,84|88,89|91,91|93,94|107,108|112,113|116,116|120,134|142,142|150,150|153,153|165,166|174,176|179,179|182,184|189,190|194,195|198,199|201,203|207,207|209,210|215,215|223,225|237,237|241,241|259,259|262,267|276,277|287,289 Q:0,11|13,23|25,27|35,36|45,52|63,69|71,74|76,82|85,87|90,90|92,92|95,106|109,111|114,115|117,119|135,141|143,149|151,152|154,164|167,173|177,178|180,181|185,188|191,193|196,197|200,200|204,206|208,208|211,214|216,222|226,236|238,240|242,258|260,261|268,275|278,286|290,297 EEEEEEEEEETT?SEEEEEEEEEE-EEE???????TT?------?SEEEEEEE----------EEEEEEE-EEES?TTEEEEE--EES-?S?B??SEEEEEEEEETT--TEE--EE-EES??----?????????EEEEEEE?TTEEEEE?TT?BTTEEEEEEEE??EEETTEE---EE?TT???TTTB??TTB??TT??S--?GGG?B??GGGS?HHHHSEE???EEEEEEEETTS?SEE-EEEEEEEEEEEEEEEEE?SS------SEEEEEEE--EEEEEEEEE---EEEEETTT 3M3R|A PF07969.6_Amidohydro_3_seed 43 615 !Q:4,4|11,11|20,20|25,25|28,31|43,58|63,63|69,69|74,75|78,81|86,87|91,93|96,96|110,110|113,114|119,120|122,128|135,145|153,154|163,178|183,183|186,186|197,197|215,228|230,230|245,248|256,270|277,277|283,284|288,288|301,303|306,307|310,310|312,313|316,317|323,326|328,332|335,335|339,340|342,342|354,354|361,374|391,412|417,418|420,421|433,433|438,438|440,445|451,451|453,459|474,477|479,479|488,494|498,499|504,506|508,510|513,513|522,523|526,526|529,570|572,574|590,593|596,596|599,601|603,604|610,611 Q:0,3|5,10|12,19|21,24|26,27|32,42|59,62|64,68|70,73|76,77|82,85|88,90|94,95|97,109|111,112|115,118|121,121|129,134|146,152|155,162|179,182|184,185|187,196|198,214|229,229|231,244|249,255|271,276|278,282|285,287|289,300|304,305|308,309|311,311|314,315|318,322|327,327|333,334|336,338|341,341|343,353|355,360|375,390|413,416|419,419|422,432|434,437|439,439|446,450|452,452|460,473|478,478|480,487|495,497|500,503|507,507|511,512|514,521|524,525|527,528|571,571|575,589|594,595|597,598|602,602|605,609|612,614 EEEE?EEEEEE?HHHHHHHH-HSEE?TT??--SHHHHHHHHHT--------------??SSSE-EEEEE?HHHH--SS??-?HHHH--TTS---SS?EEEEETTSSEEEE?HH--HHHH--H??--???TTEETT-----------TTEEEHH--HHHHHHHH----------------HHHT-TS?HHHHHHHHHH-HHHHHHHTTEEEEEEEE--------------E?HHHHHHHHHHHHTT?-??SEEEEEE--------------?GGGHHH-HHHHT??SEE?SSEEEEEEEEES???TT--TT?S??SS?-BTTBT----T?????SS?HHH--H-HHHHHHHTTTT?EEEEEE-------------?SHHHHHHHHHHHHHHT???-------------------EEEE??B??HHHHHHHHHHT?EEEE?T------THHHH?T-------THHHHHHHHHGGGB----T?HHHHHHHS------?EEE??TTTT---S???HH-HHHHHHHH??SS?GG------------------------------------------G???HHHHHHHTTHHHHHH----TT?TT?--S??STTSB??EEE 1FWI|C PF07970.7_COPIIcoated_ERV_seed 51 308 !Q:0,2|6,15|17,29|32,44|46,53|55,58|60,72|93,121|124,127|129,132|142,147|149,155|158,172|174,176|183,190|193,194|197,200|216,218|220,220|222,224|227,227|241,259|261,261|270,270|277,307 Q:3,5|16,16|30,31|45,45|54,54|59,59|73,92|122,123|128,128|133,141|148,148|156,157|173,173|177,182|191,192|195,196|201,215|219,219|221,221|225,226|228,240|260,260|262,269|271,276 ---GGG----------S??---------??TT?????????????G--------G----G-----------??EEEEEEEEEESSSEEEEEEE??--?????????---------------?GG----G????EEEEEEEES------S?-----?TT??------------?T---TTTEEE?------?TT?-TT---?EEEEEEEEEEEEETT---T?S---SS?EEEEEEEEEEHHH????-------------??S?EEEEEEEE?SEEEEE????--------------------------- 3ZLC|A PF07971.7_Glyco_hydro_92_seed 187 1086 !Q:1,1|5,7|9,9|15,16|19,23|28,34|36,37|47,50|57,59|63,67|70,82|85,87|92,93|105,105|110,110|113,114|116,125|127,131|133,137|141,145|163,164|166,173|175,180|184,184|187,196|199,199|203,208|211,250|253,262|265,266|268,283|300,300|303,303|317,317|319,320|323,332|335,336|344,352|363,365|368,369|371,386|388,394|397,397|404,405|411,423|425,425|428,428|431,443|446,446|449,459|465,465|470,473|475,497|501,501|504,506|508,514|534,534|536,538|540,550|552,553|555,584|587,587|589,589|607,645|650,651|653,661|664,673|675,685|687,697|699,704|706,714|716,717|719,731|733,736|738,744|749,749|752,752|755,758|763,765|768,768|774,774|781,798|801,811|823,827|829,829|834,835|837,838|841,842|850,850|854,860|877,877|879,879|896,898|902,903|905,905|908,908|910,913|927,927|932,932|937,939|946,948|956,958|960,984|988,998|1000,1000|1004,1007|1009,1010|1013,1022|1025,1036|1049,1056|1059,1060|1066,1068|1071,1072|1074,1074|1085,1085 Q:0,0|2,4|8,8|10,14|17,18|24,27|35,35|38,46|51,56|60,62|68,69|83,84|88,91|94,104|106,109|111,112|115,115|126,126|132,132|138,140|146,162|165,165|174,174|181,183|185,186|197,198|200,202|209,210|251,252|263,264|267,267|284,299|301,302|304,316|318,318|321,322|333,334|337,343|353,362|366,367|370,370|387,387|395,396|398,403|406,410|424,424|426,427|429,430|444,445|447,448|460,464|466,469|474,474|498,500|502,503|507,507|515,533|535,535|539,539|551,551|554,554|585,586|588,588|590,606|646,649|652,652|662,663|674,674|686,686|698,698|705,705|715,715|718,718|732,732|737,737|745,748|750,751|753,754|759,762|766,767|769,773|775,780|799,800|812,822|828,828|830,833|836,836|839,840|843,849|851,853|861,876|878,878|880,895|899,901|904,904|906,907|909,909|914,926|928,931|933,936|940,945|949,955|959,959|985,987|999,999|1001,1003|1008,1008|1011,1012|1023,1024|1037,1048|1057,1058|1061,1065|1069,1070|1073,1073|1075,1084 E-SSE---E-EEEEE--EE?----TTEE-------E--EEEEEEESS?---HHHHHH---HGG-----GG-------------TT?-?HHHH--HHHHHHHHHHH-HTTE-EE--E----------S-----S?----HHH-----HHHHHHHHHHTTSSSEE??E--------E-----?TTS?EE----------EE?TTT-??---EE----------------------------------------ES??--------EE?-E----------------EHHHHTTTHHHHHHHH?HH-HHHHHHHHHHHHH-H--HH----------SS??SEESSSB?--??????THHHHHHHHH---HT--T------------??-?S?------HH-HHHHHH--HHHHT------------?B?SS?TT-------------SB?TT-----------HHHHH-HHSS?--?S-----------------------SSS?SS---H-------HHHHHHHHHHHHHHHHHHH-H---T-----------T??H------------------------------HH-H-HHHHHHGGGGGGGEETT---------------------------------------TTEE??B------?--TT----------S----?------B?----------S------S-------??T--T-------------B?---S-------TTSS-SS?HH----HHTT??-TT?HHHHH-HHHTSH------------------HH-----------HHHHHHHHHHS-????B?TTTT--S??HH--HHHHHHH?STT?----?-TTSGGGTTGGGGGGGG-T?HHHHHHHHHHHHHHSB?--SST--T?BS-S--??TTTHHHHHHHHHH-HTEE?SSTT---SSEEEE???SSSEEEE---E?------------------------TTS-------?---E-EEE----E?-TT??--------SS-?---------?EEEEEEETTEEE?----?--SE--EEHHH---HT--T?EEEEEEEESS? 2WVZ|A PF07972.6_Flavodoxin_NdrI_seed 86 162 !Q:2,5|8,8|15,19|23,23|25,28|31,32|35,42|45,56|58,58|65,66|72,73|77,84|86,86|106,115|120,120|127,127|141,142|151,152 Q:0,1|6,7|9,14|20,22|24,24|29,30|33,34|43,44|57,57|59,64|67,71|74,76|85,85|87,105|116,119|121,126|128,140|143,150|153,161 EE???-TT?HHHHHH-----HHH?S--??EE??SS--------TT??------????S?EEEEEE??TTSSS--SSS--------S?HHHHHHHTSHHHHHHEEEE----------EEEE?GGGGGG-TTHHHHHHHHHHT??EEEEEETT??HHHHHHHHH 2X2O|A PF07973.9_tRNA_SAD_seed 219 84 !Q:0,0|4,8|11,11|13,15|17,33|36,41|44,45|47,49|51,51|55,58|73,73|77,77 Q:1,3|9,10|12,12|16,16|34,35|42,43|46,46|50,50|52,54|59,72|74,76|78,83 ?EEE-----EE-T---T-----------------EE------EE??S???S?GGG?--?EEEEEEEEEEETTS?SSS?EEEEEE 3RFN|A PF07974.8_EGF_2_seed 51 51 !Q:2,2|6,9|15,17|19,19|23,30|36,37|40,43|45,45 Q:0,1|3,5|10,14|18,18|20,22|31,35|38,39|44,44|46,50 TB?TTS----SBTSS---S?EEE--------TTEEE??ST----T?BSTTS 3FCS|B PF07975.7_C1_4_seed 16 63 !Q:8,8|12,30|34,35|40,41|43,43|55,55|61,62 Q:0,7|9,11|31,33|36,39|42,42|44,54|56,60 EETTTTEE?TTS-------------------EEE??TTTT??B?HHHHHTTTTTS?SSSTT?- 1Z60|A PF07976.7_Phe_hydrox_dim_seed 78 277 !Q:4,9|12,12|16,28|30,30|32,64|67,74|80,80|85,88|96,97|105,106|110,110|117,118|123,123|125,129|132,135|137,137|149,149|152,152|159,159|162,182|184,184|187,187|190,190|197,197|200,200|204,205|208,208|211,211|213,213|217,217|225,234|236,238|243,246|250,257|259,260|266,267|269,269|271,271|275,276 Q:0,3|10,11|13,15|29,29|31,31|65,66|75,79|81,84|89,95|98,104|107,109|111,116|119,122|124,124|130,131|136,136|138,148|150,151|153,158|160,161|183,183|185,186|188,189|191,196|198,199|201,203|206,207|209,210|212,212|214,216|218,224|235,235|239,242|247,249|258,258|261,265|268,268|270,270|272,274 HHTT??????SS-SSS----------???T-T---------------------------------GG--------GBTTS?TTSB????EEEETTT??EEEGGGG??SSS?EEEEEE??TTTT-T--?--TT----S-HHHHHHHHHHH?TT?HHHHHS?TT---------------------S?TT-SS-EEEEEE?SS?GGG??GG-GS?G-GGS?EETTTTE----------E???SEEE?-??SST--------T??HHHHT--T-B?TTT-? 2DKH|A PF07977.8_FabA_seed 51 147 !Q:0,2|5,5|7,9|19,19|25,25|33,34|37,37|48,51|72,74|79,80|83,90|98,98|100,102|105,106|118,120|127,127|147,147 Q:3,4|6,6|10,18|20,24|26,32|35,36|38,47|52,71|75,78|81,82|91,97|99,99|103,104|107,117|121,126|128,146 ???TT-T???SEEEEEESS?TTTTS?EEEEEEE??TT?HHHHHSSTTS????HHHHHHHHHHHHHHHHHHTT?-?SEEE--EE--------EESEEEE?S???TT??EEEEEEEEEEE---EESSSE-EEEEEEEEEETTEEEEEEE- 4B0B|A PF07978.8_NIPSNAP_seed 42 122 !Q:2,3|13,13|18,18|35,35|44,58|63,63|75,75|89,89|93,93|104,105|117,117|120,120 Q:0,1|4,12|14,17|19,34|36,43|59,62|64,74|76,88|90,92|94,103|106,116|118,119|121,121 EE--EEEEEESTT?HHHH-HHHHHHHTHHHHHHHH?EEEEEEEE---------------EESB-SSEEEEEEEES?HHHHHHHHHHHHH?HHH-HHHGGGTTTT--EEEEEEEEEEE?TT?S 2AP6|A PF07979.6_Intimin_C_seed 14 116 !Q:0,0|4,4|14,14|24,25|31,33|41,46|52,52|63,63|65,66|70,73|96,101|108,108|115,115 Q:1,3|5,13|15,23|26,30|34,40|47,51|53,62|64,64|67,69|74,95|102,107|109,114 ?SEE-EEEEEEEEE?HHHHHHHHH--HHSSB???SHHHHHH------HHHHH?SGGGSGGGSS?S??EEE????HHHHHHTEEEEEETTTEEEEEE------EESSSS?EEEEEE? 2ZWK|A PF07980.6_SusD_seed 151 798 !Q:5,10|15,16|22,22|29,29|31,32|37,63|65,71|73,82|90,138|143,148|152,152|155,155|163,163|169,169|175,175|179,179|182,182|185,255|261,262|265,266|272,272|279,279|283,283|286,286|290,311|315,319|321,328|332,336|338,341|355,357|361,372|376,376|378,384|387,391|394,395|401,404|406,408|410,411|415,480|482,520|527,529|534,534|544,544|546,546|548,548|556,636|638,638|665,668|673,750|752,755|762,774|777,786|788,795|797,797 Q:0,4|11,14|17,21|23,28|30,30|33,36|64,64|72,72|83,89|139,142|149,151|153,154|156,162|164,168|170,174|176,178|180,181|183,184|256,260|263,264|267,271|273,278|280,282|284,285|287,289|312,314|320,320|329,331|337,337|342,354|358,360|373,375|377,377|385,386|392,393|396,400|405,405|409,409|412,414|481,481|521,526|530,533|535,543|545,545|547,547|549,555|637,637|639,664|669,672|751,751|756,761|775,776|787,787|796,796 TTEEE------EEEE??SSTTT?HHHHHS?S??TTTS--------------------------?S???????B---------?HHHHHHS------------------------------------------------?BTTS??????TTS?TT?EEETTTS?TTSSB?HHHHH-HEE?TT?EE?----------------------------------------------------------------------TTSTT??EE??TTTTS?TTSTTS?SSS?EE?TTS?---------------------TTT?????S????????EEE-----E----EEEHHHHHHHHHH---HHH------------HHT?H-------HH-----HH--HHHHH----H---H--HTT------------------------------------------------------------------T????????-------------------------------HHHHHH---HHHH-HHHHHTTTS-S?H-HHHHHHH---------------------------------------------------------------------------------T?HHHHSSEEEEEEESSSSEEEEEEEEE????GGGG------------------------------------------------------------------------------S????HHHHHH?------------SS??--?-?---T--------T? 3CK7|A PF07983.8_X8_seed 189 106 !Q:0,0|5,7|11,16|31,35|37,39|41,41|47,50|53,62|64,64|67,70|87,89|92,92|94,94|98,99|101,101 Q:1,4|8,10|17,30|36,36|40,40|42,46|51,52|63,63|65,66|71,86|90,91|93,93|95,97|100,100|102,105 ?EEEE-?-TTS-----?HHHHHHHHHHHTTT-----S---S-SSSTT-???SS----------S?SS?--?TTHHHHHHHHHHHHHH---TS-S-GGG??S?SSEE 2W62|A PF07986.7_TBCC_seed 52 141 !Q:1,2|8,8|11,11|16,22|24,24|27,27|33,33|36,36|41,41|53,53|70,70|82,84|87,92|95,95|103,109|111,111|122,122|124,125|128,132|134,137 Q:0,0|3,7|9,10|12,15|23,23|25,26|28,32|34,35|37,40|42,52|54,69|71,81|85,86|93,94|96,102|110,110|112,121|123,123|126,127|133,133|138,140 T??EEEES?BS?EEEE------?S?BS?EEEES?BS?EEEE-EEEEEEEEEES?EEEEEEEEEEEEEEES?EEEEEEEEESS-??EE------ES?EEEEEEE----???B?TTHHHHHHHT-T??TT???-?S?--?EES 2YUH|A PF07987.6_DUF1775_seed 87 188 !Q:1,1|4,6|8,10|13,13|17,18|20,20|28,30|33,35|46,48|55,57|67,67|69,81|84,84|93,93|96,98|100,100|103,105|115,121|128,129|138,142|147,147|149,162|165,179|181,182|186,186 Q:0,0|2,3|7,7|11,12|14,16|19,19|21,27|31,32|36,45|49,54|58,66|68,68|82,83|85,92|94,95|99,99|101,102|106,114|122,127|130,137|143,146|148,148|163,164|180,180|183,185|187,187 S?EE---E?--SS?BTT??E-EEEEEEE???SS?-?EEEEEEEEEE---ESEEEE???TTEEEEEEE?T-------------TS?EEEEEEEE?TT???B?TT--?EEEEEEEEE???----SSSEEE??EEEEETTS----?EEEE?B????----?????-SS---------------B??EEE?B 3ESM|A PF07988.7_LMSTEN_seed 6 49 !Q:0,26|48,48 Q:27,47 --------------------------?HHHHHHHHHHHHHHHHHHHHT? 1SB0|B PF07991.7_IlvN_seed 45 177 !Q:4,4|6,6|11,12|28,30|35,36|39,43|45,45|55,55|59,59|67,67|73,73|75,75|91,92|95,97|103,104|113,115|118,118|128,128|140,143|150,151|153,153|156,156|158,158|176,176 Q:0,3|5,5|7,10|13,27|31,34|37,38|44,44|46,54|56,58|60,66|68,72|74,74|76,90|93,94|98,102|105,112|116,117|119,127|129,139|144,149|152,152|154,155|157,157|159,175 HHHT-S?EEEE??SHHHHHHHHHHHHTT?-?EEEE??TT?----H-HHHHHHHTT?EEE?HHHHHHT?SEEEE?S?HHHHHHHHHHHTGGG??TT?--EEEES??HHHHTTSS???TT?EEEEEEESS?SHHHHHHHHTT????EEEEEE--E?SS-S?HHHHHHHHHHHTTHHHH? 3CE6|A PF07992.9_Pyr_redox_2_seed 139 558 !Q:5,6|19,24|28,30|36,46|49,49|56,56|79,80|87,88|90,90|93,112|128,128|130,130|136,147|151,151|155,155|158,159|171,180|189,192|197,201|204,204|210,213|216,216|218,225|228,228|230,231|233,251|254,256|259,259|266,266|269,298|300,302|308,309|325,325|341,341|357,403|442,442|444,444|449,449|454,456|462,463|465,475|477,494|497,497|499,503|505,509|511,513|515,538|540,542|549,549|554,554|557,557 Q:0,4|7,18|25,27|31,35|47,48|50,55|57,78|81,86|89,89|91,92|113,127|129,129|131,135|148,150|152,154|156,157|160,170|181,188|193,196|202,203|205,209|214,215|217,217|226,227|229,229|232,232|252,253|257,258|260,265|267,268|299,299|303,307|310,324|326,340|342,356|404,441|443,443|445,448|450,453|457,461|464,464|476,476|495,496|498,498|504,504|510,510|514,514|539,539|543,548|550,553|555,556 SEEEE??SHHHHHHHHHHH------HTT??-EEEEE-----------SS?TTHHHH-HTSHHHHHHHHHHHHHHHHHHT-?GGGTEE??S?EE-------------------?HHHHHHHHHHHHHHH-H-HHHHH------------HHH-TTT?EE--EESEEEEEETT----------EEEEEETT----EEEE-----EE?SEEEE???-EE-E?------?BT-T--B---------------?-??SS---EE?HHHHHT?SS?----------------------------?S---EEEEE??SHHHHHHHHHHHHTT?EEEEEESSSSSSTTS?HHHHHHHHHHHHHTT----------------------------------------------?EEEESEEEEEEEEETTEEEEEEEETTEEEEEEESEEEE?S?EEES?SSSS---TTTTT??B----------?T------------------TS?B--???T-----T?--B?-----------------------S---STTEEE?GGGS-SS? 1O94|A PF07993.7_NAD_binding_4_seed 102 411 !Q:2,2|17,18|22,23|26,26|32,32|34,35|41,44|55,55|58,58|65,72|86,87|93,95|98,99|107,108|112,113|118,119|122,122|126,128|130,131|133,134|152,160|162,162|165,173|180,186|194,194|198,199|202,249|251,251|256,257|261,262|268,269|289,295|297,301|307,307|311,347|353,357|372,372|374,374|379,379|382,384|388,399 Q:0,1|3,16|19,21|24,25|27,31|33,33|36,40|45,54|56,57|59,64|73,85|88,92|96,97|100,106|109,111|114,117|120,121|123,125|129,129|132,132|135,151|161,161|163,164|174,179|187,193|195,197|200,201|250,250|252,255|258,260|263,267|270,288|296,296|302,306|308,310|348,352|358,371|373,373|375,378|380,381|385,387|400,410 EE?TTSHHHHHHHHHHH--HHS-?TT?EEEEE-E?-SSSHH----HHHHHHHGGG?SS?HHHHHH--------HHHHHTTTEEEEE??TTSGG---GG??HHHHHHH--HHH??EEEE??SS?SBS---S??E--EHHHHHHHHHHHHHHHT---------S-SS??------?EEEEEE-------GGGGTTS?TTT??SS------------------------------------------------S?HHHH??EEE??TTSEE-?HHHHHHHHHHHHHHHHHHH???----E-----EEEEE?EEE?-----------------------------------?SSSSS--???TTBHHHHHHHHHHH-H?EEES?SB???TTS??----??????EEEHHHHHHHH 4F6L|A PF07994.7_NAD_binding_5_seed 37 566 !Q:26,27|36,41|44,44|49,49|56,58|62,62|73,76|86,86|88,90|92,94|102,105|108,108|110,110|124,135|137,137|139,141|143,143|147,147|154,156|159,162|166,169|192,192|194,200|206,206|208,223|241,241|244,246|257,258|260,265|268,269|273,273|277,281|283,284|295,297|304,305|323,323|335,335|343,362|364,403|406,406|416,418|423,424|427,427|444,444|448,448|486,487|489,513|516,516|518,521|523,525|527,527|529,529|539,544|548,552 Q:0,25|28,35|42,43|45,48|50,55|59,61|63,72|77,85|87,87|91,91|95,101|106,107|109,109|111,123|136,136|138,138|142,142|144,146|148,153|157,158|163,165|170,191|193,193|201,205|207,207|224,240|242,243|247,256|259,259|266,267|270,272|274,276|282,282|285,294|298,303|306,322|324,334|336,342|363,363|404,405|407,415|419,422|425,426|428,443|445,447|449,485|488,488|514,515|517,517|522,522|526,526|528,528|530,538|545,547|553,565 EEEEEETTTSHHHHHHHHHHHHHHTT??EEETTEEE--????TT?HHHH?EEEEEE?--SSS?EEEEEGGGSS????GGGEEEEEE?S---S???HHHHHHH----HT?S?HHHHHHTHHHHTT?---------??B?B???G-GGS?STTTTT???BS?-??TTS????TTHHHHHHHHHHHHHHHHHHTT?S------?EEEEE?S????------?????-TTTSSSHHHHHHHHHTT?TT-??HHHHHHHHHH--H------HT??EEE?SSS???-?H--HHHHHHHHHT??-EEESSB??HHHHHHHHHHHHHHHTT?EEEEEEEEEEE?SHHHHHT????????????????????T----------------------------------------TT?TTTSBTTTB???EEEE??EE?GGGTTEEEEEEEEEEE?GGG?EEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHTEEEEE??S-------------------------SS?S????B???S-B?GGGGGGBSS??--??TTS?????HHHHHHHHHHHHH 3QW2|A PF07995.6_GSDH_seed 164 632 !Q:4,6|10,15|18,19|21,24|27,29|31,31|37,37|46,53|59,63|66,90|93,97|99,99|107,107|111,112|116,124|134,155|157,161|164,165|167,169|172,172|180,182|185,187|193,196|204,207|210,212|215,216|219,224|228,233|235,239|242,242|249,250|253,263|266,271|275,275|277,279|282,282|291,291|295,297|300,300|304,311|313,321|324,337|340,340|342,342|348,349|354,354|371,371|375,381|386,388|391,391|393,394|399,399|403,403|406,409|412,429|432,433|437,437|440,448|450,452|455,455|460,466|474,478|481,481|483,483|485,485|487,492|503,503|505,511|521,521|523,523|525,539|542,545|554,578|582,584|591,591|594,594|596,597|603,608|610,612|616,618|620,628 Q:0,3|7,9|16,17|20,20|25,26|30,30|32,36|38,45|54,58|64,65|91,92|98,98|100,106|108,110|113,115|125,133|156,156|162,163|166,166|170,171|173,179|183,184|188,192|197,203|208,209|213,214|217,218|225,227|234,234|240,241|243,248|251,252|264,265|272,274|276,276|280,281|283,290|292,294|298,299|301,303|312,312|322,323|338,339|341,341|343,347|350,353|355,370|372,374|382,385|389,390|392,392|395,398|400,402|404,405|410,411|430,431|434,436|438,439|449,449|453,454|456,459|467,473|479,480|482,482|484,484|486,486|493,502|504,504|512,520|522,522|524,524|540,541|546,553|579,581|585,590|592,593|595,595|598,602|609,609|613,615|619,619|629,631 ESSE---EEE------EE?-S----TT?-?E-EEEET-TTEEEEEE--------TTTEE-????BS?--------?-??----------??ST-----T?SEEEEEE?TTH--HHH--------?EEEEEEEEE---------------------?S-----SS-?E---EE-EEEEEEE--?TT---SSBEE----EEEEEEE?---SS?-?BS--SS?????-EEE?-----S-----SS-EEEEEE??TT?----------GG------GGG?T---TS?TTEEEEEE-TTS???TT?TTT--------T---------ST--------------TS?T-TEEEE??SEEE-EEEEETTTTEEEEEEE?SBS?------EEEE???TT?B??TTTB?SSB?TT----SS----------------??TT??BSS?TT---------S???SE-EESS?----??EEEEEEE??---SS-S-G-G------GTTEEEEEET-T-------TTEEEEEEE-E-T---------------TE----EEEEEEES-------------------------GGG???EEEEEE?TT-S-?EEEEE?-----S---TTE---E---------EEE 2WFX|B PF07996.6_T4SS_seed 50 234 !Q:0,16|21,24|38,51|59,59|67,70|75,76|83,83|89,96|106,108|111,111|113,114|118,118|125,125|133,139|158,158|187,188|233,233 Q:17,20|25,37|52,58|60,66|71,74|77,82|84,88|97,105|109,110|112,112|115,117|119,124|126,132|140,157|159,186|189,232 ?????????--------STTH----HHHHHHHHHHHHH--------------HHHHHHH-HHHHHHH----HHTT??GGGSSS-TTTSS??????-?TTTTHHHHH---HH?S??SSS?HHHHSS?SHHHHTT?-----?TTTTHHHHHHHHHHTTTT?HHHHHHHHHHHHHHHHHHHHHHHHHTTS??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTS? 1R8I|A PF07997.6_DUF1694_seed 33 139 !Q:0,2|5,7|16,17|19,22|35,36|54,57|67,71|74,75|85,85|88,88|102,103|108,110|113,118|126,126|130,133|135,136|138,138 Q:3,4|8,15|18,18|23,34|37,53|58,66|72,73|76,84|86,87|89,101|104,107|111,112|119,125|127,129|134,134|137,137 -??HH---HHHHHHTT??S--??SSHHHHHHHTTT??GGGEEEEEEHHHHTSSS??--HHHHHHHHT----?SS--EEEEEETTS?HH-HHHHHHHHHHHTT??EEEE???SS??----SEEEEEE-ESS????S??S? 2OHW|A PF07998.6_Peptidase_M54_seed 5 199 !Q:0,0|10,11|13,15|33,33|35,35|37,37|43,56|79,80|82,85|89,96|103,103|106,106|109,109|111,111|117,117|127,127|131,138|162,165|167,167|174,175|185,185|188,189 Q:1,9|12,12|16,32|34,34|36,36|38,42|57,78|81,81|86,88|97,102|104,105|107,108|110,110|112,116|118,126|128,130|139,161|166,166|168,173|176,184|186,187|190,198 ?EEEEEESSS??T---THHHHHHHHHHHHHHHH?S?E-EEEEE????----------GGGEETTTTEEEHHHHHHHHHT??S??--SEE--------EEEESS?EE?TT?S?BSEEE?SSSSEEEEE?TTT??------SSHHHHHHHHHHHHHHHHHHHTT????S?TTSTTS??SSHHHHHHS?SS??HHHHHHHHH 3ZVS|A PF08000.6_bPH_1_seed 55 141 !Q:0,1|12,16|29,32|35,36|43,43|66,66|78,79|89,89|94,94|101,101|106,106|109,109|112,119|123,123|127,127|140,140 Q:2,11|17,28|33,34|37,42|44,65|67,77|80,88|90,93|95,100|102,105|107,108|110,111|120,122|124,126|128,139 ??TTHHHHHHHT??--?HHHHHHHHGGGS?---TT??EEEEEE?SSEEEEEESSEEEEEEEESTTS?EEEEEEEEGGG--EEEEEEEEE-STTS?EEEEEE-EETT?SS?EE--------EEE?TTS?HHHHHHHHHHHH? 3HSA|A PF08002.6_DUF1697_seed 88 155 !Q:0,0|7,7|10,10|12,20|33,33|49,53|55,55|57,57|73,73|76,79|94,95|101,110|119,119|122,123|135,137|139,139|145,145|147,148|153,153 Q:1,6|8,9|11,11|21,32|34,48|54,54|56,56|58,72|74,75|80,93|96,100|111,118|120,121|124,134|138,138|140,144|146,146|149,152|154,154 ?EEEEEE?SS?S????????-HHHHHHHHHHHT?EEEEEETTTTEEEEE-----E?S?HHHHHHHHHHHHHHH?TT????EEEEHHHHHHHHTT??GGGGS----??----SEEEEEEE?TT??HHHHHHHHHTS???S-EEEEE?S--SEEE-E 2HIY|A PF08005.7_PHR_seed 18 202 !Q:1,2|6,8|13,14|17,19|29,30|40,45|61,98|116,116|118,119|121,121|134,134|137,138|149,150|157,158|162,162|166,166|170,171|179,181|187,188|194,195 Q:0,0|3,5|9,12|15,16|20,28|31,39|46,60|99,115|117,117|120,120|122,133|135,136|139,148|151,156|159,161|163,165|167,169|172,178|182,186|189,193|196,201 E??SEE---EEEE??SS?-?EEEEEEESS?-EEEEEEEEE?-----BSSSSEEEEEEEEEE--------------------------------------ETTTTEEEEEEEEEEEE?S-?S?EEEEEEEEEEEE?TT??EEEEEEEESS?-EEEEES??SEE-EEE?TTT??EEEEEEE???SSSTT??SSSBS??EEEEEE 3GBW|A PF08007.7_Cupin_4_seed 26 427 !Q:11,12|16,17|19,19|21,24|31,32|36,36|45,46|49,56|73,75|77,80|83,84|96,96|99,104|108,108|113,113|130,130|139,139|143,144|146,147|149,150|162,162|169,173|181,181|184,189|193,198|201,201|206,206|209,209|214,214|217,217|224,224|227,228|237,237|240,240|246,276|292,310|317,318|325,325|332,335|348,349|358,359|366,367|378,383|391,391|395,398|405,412|415,415|421,421 Q:0,10|13,15|18,18|20,20|25,30|33,35|37,44|47,48|57,72|76,76|81,82|85,95|97,98|105,107|109,112|114,129|131,138|140,142|145,145|148,148|151,161|163,168|174,180|182,183|190,192|199,200|202,205|207,208|210,213|215,216|218,223|225,226|229,236|238,239|241,245|277,291|311,316|319,324|326,331|336,347|350,357|360,365|368,377|384,390|392,394|399,404|413,414|416,420|422,426 HHHHHHHTTTT??EEE??S?T----TTTTTS??HHH-HHHHHHHS??BB--------TTTEEEEEEETTEEEE???S----SB??HHHHHHHHHTT?EE------EES?GGGT?HHHHHHHHHHHHHHTS?EEEEEEEE?SSB??S??B??SSEEEEEEEEE?EEEEEE?---?SSGGGTT?SS??????GGG??--??SE-EEEE?TT?EEEE?TT?EEEEEB?SS??EEEEEEEE?TT?BHHHH-------------------------------HHHHHHHHHHHHHHH------------------?GGGGSB??TTGGGT?SGGGTT-???HHHHHHHHHHHH--HHHHHGGG??HHHHHH--HHHHHHHHHS??????HHHHHTS-GGG????EETTEE????????TT?EEEES?TTSEE 1MZE|A PF08008.7_Viral_cys_rich_seed 15 90 !Q:0,9|14,14|19,28|32,33|42,42|52,89 Q:10,13|15,18|29,31|34,41|43,51 ????????--SSEE?SSSS????-----?EEE??SSEEEEEE?SSSSEEEEE?-----------------------------???????? 1XJ1|A PF08013.6_Tagatose_6_P_K_seed 31 443 !Q:0,20|25,28|43,44|46,46|57,57|60,60|65,66|83,84|104,104|124,125|130,132|134,135|139,141|144,145|164,177|183,206|226,227|239,241|243,243|246,246|249,249|252,254|271,271|277,278|281,282|300,300|322,325|329,329|332,332|344,344|352,353|366,366|369,369|394,397|405,405|418,418|440,442 Q:21,24|29,42|45,45|47,56|58,59|61,64|67,82|85,103|105,123|126,129|133,133|136,138|142,143|146,163|178,182|207,225|228,238|242,242|244,245|247,248|250,251|255,270|272,276|279,280|283,299|301,321|326,328|330,331|333,343|345,351|354,365|367,368|370,393|398,404|406,417|419,439 ???????-?????????????EEEE????HHHHHHHHHHHHHS?-S?EEEEEETTTS?TT?TTTT??HHHHHHHHHHHHHHTT??GGGEEEEEEEESSGGGTTS?HHHHHHHHHHHHHHHHTTT??EEEE???B??SSS?--SB??HHHHHHHHHHHHHHHHHT----?-????????EEEEE????????--??????--??????HHHHHHHHHHHHHHHHHHT?-HHHHTTEEEEE???S?EE?SS?EE???TTTTSHHHHGGGTSTT?EEEES??TT??HHHHHHHHHTTEEEEEE?HHHHHHHHHHHHHHHHHHHHH?---TTS?SS?HHHHHHHHHHH?THHHHTT??SSHHHHHHHHHH?TT?GGGGTTTSHHHHHHHHHHHHHSTT????HHHHHHH?GGGHHHHHTTSS?SSHHHHHHHHHHHHHHHHHHT??? 3TXV|A PF08020.6_DUF1706_seed 42 190 !Q:1,4|28,29|35,37|39,50|52,52|55,55|78,79|83,86|89,89|92,93|112,113|136,136|146,146|153,153|157,159|181,184 Q:0,0|5,27|30,34|38,38|51,51|53,54|56,77|80,82|87,88|90,91|94,111|114,135|137,145|147,152|154,156|160,180|185,189 B????SSHHHHHHHHHHHHHHHHHGGGG??GGGTT???T------------T?SS?HHHHHHHHHHHHHHHHHHHHHH--HTT????SS?SS??GGGHHHHHHHHHHHHTTS-?HHHHHHHHHHHHHHHHHHHHHS?HHHHHSSSS?HHHHTT?SSS???HHHHHHHHTHHHHHHHHHHHH----HHHHH 4N6C|A PF08021.6_FAD_binding_9_seed 40 146 !Q:19,19|25,28|30,32|35,35|42,43|47,77|84,85|91,96|104,108|111,119|128,129|132,132|139,139|141,141|143,146 Q:0,18|20,24|29,29|33,34|36,41|44,46|78,83|86,90|97,103|109,110|120,127|130,131|133,138|140,140|142,142 EEEEEEEEETTEEEEEEES-GGGTT??--S?-?TT?EEEEEE??TTS?-----------------------------?EEEEEE??EEETT------EEEEEEE??---SS?-------?HHHHHHHH??TT?EEEEEE-E-E???- 2GPJ|A PF08023.7_Antimicrobial_2_seed 18 37 !Q:0,0|35,36 Q:1,34 ?HHHHHHHHHTTTTHHHHHHHTSSSHHHHHHTTTT?? 2K10|A PF08027.6_Albumin_I_seed 4 126 !Q:0,23|28,28|31,31|37,37|44,45|49,49|54,54|57,125 Q:24,27|29,30|32,36|38,43|46,48|50,53|55,56 ---------------------???EEEE?TT?SSGGG?SSSEEE??SSS?EEEE?TT?-------------------------------------------------------------------- 1JU8|A PF08028.6_Acyl-CoA_dh_2_seed 37 148 !Q:23,23|28,30|35,41|73,76|81,85|96,99|127,127|146,146 Q:0,22|24,27|31,34|42,72|77,80|86,95|100,126|128,145|147,147 HHHHHHHHHHHHHHHHHHHHHHH-HHHH---HTTT???????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH----HTTT???-?HHHHHHHHHH----HHHHHHHHHHHHHHHHHHTGGGGGBTT?HHHHHHHHHHHHTTSGGG?H 1UKW|A PF08029.6_HisG_C_seed 39 88 !Q:22,27|29,31|35,35|40,45|49,51|76,76|84,84|86,87 Q:0,21|28,28|32,34|36,39|46,48|52,75|77,83|85,85 HTTTEEEEEEEEEGGGHHHHHH------H???SSS?EEEE?----?SSS--?EEEEEEEEETTTHHHHHHHHHTTT?EEEEEEE?S?? 2VD3|A PF08030.7_NAD_binding_6_seed 21 318 !Q:28,56|58,58|61,65|75,75|87,88|100,100|113,262|267,270|279,285|292,292|300,303|305,305 Q:0,27|57,57|59,60|66,74|76,86|89,99|101,112|263,266|271,278|286,291|293,299|304,304|306,317 SSEEEEEEEGGGHHHHHHHHHHHHHHHH-----------------------------H?TT?????EEEEEEEES?TTTTHHHHHHH--HHHHHHHHHTT?TTSEEEEEEETT????---------------???------------?????-----------------------------------------------------------------------?????-???????-------------------------??EEES-???HHHHHHHH-------HHHSTT?EEEEEEE----S?HHHHHHHHHHHH 1IB0|A PF08031.7_BBE_seed 67 74 !Q:0,1|5,6|10,13|17,29|35,35|44,44|47,47|59,61|64,65|67,68|71,73 Q:2,4|7,9|14,16|30,34|36,43|45,46|48,58|62,63|66,66|69,70 ??TTS??GGG????TTS----------???HHHHH-HHHHHHSS-TH-HHHHHHHHHHH--?TT??S??TT??? 2Y3S|A PF08032.7_SpoU_sub_bind_seed 127 99 !Q:14,18|21,22|28,29|35,40|43,47|49,50|61,62|64,64|70,70|74,74|81,81|83,85|93,98 Q:0,13|19,20|23,27|30,34|41,42|48,48|51,60|63,63|65,69|71,73|75,80|82,82|86,92 EEESHHHHHHHHHS---?-GG--GEEEE--EEESS---???TT-----T--HHHHHHHHHH--T?EEEEE?SHH-HHHTTT-S???TTEEEEE?????? 1IPA|A PF08033.7_Sec23_BS_seed 141 160 !Q:10,10|22,22|25,33|35,36|39,39|42,56|59,59|61,61|70,70|73,74|80,83|86,129|142,142|145,146|157,157|159,159 Q:0,9|11,21|23,24|34,34|37,38|40,41|57,58|60,60|62,69|71,72|75,79|84,85|130,141|143,144|147,156|158,158 EEEEEEEEEE?TTEEEEEEESS?EE???----??T--TB?SS-------------??SB?S?SEEEEEEE?TT??EEEEE----EE??---------------------------????-?--????-??EEEEEEEEEEET-TS-?EEEEEEEEEE?B? 1M2V|A PF08036.6_Antimicrobial_6_seed 3 39 !Q:0,2|12,12|25,26 Q:3,11|13,24|27,38 ???HHHHHSTTS?STTTHHHHHHTT??SEEEEETTEEEE 2E2F|A PF08037.6_Attractin_seed 2 55 !Q:0,1|14,14|18,18|23,23|43,43|50,51|53,54 Q:2,13|15,17|19,22|24,42|44,49|52,52 ??TTTTHHHHHHHS?SSS?TTTS?SSHHHHHHHHHGGGHHHHT?TTSSSS??S?? 1T50|A PF08041.6_PetM_seed 21 38 !Q:2,3|29,29|31,33|35,37 Q:0,1|4,28|30,30|34,34 HH--HHHHHHHHHHHHHHHHHHHHHHHHT-T---T??? 2ZT9|F PF08059.8_SEP_seed 44 78 !Q:13,13|19,19|33,35|43,43|45,45|47,47|59,61|66,67|73,73 Q:0,12|14,18|20,32|36,42|44,44|46,46|48,58|62,65|68,72|74,77 EEEESSEEEETTS?EEETT?TTTHHHHHHHHHT???HHHHTTS?S-S?EEEEEEEEETT???SSSS--SSTTS?SSSS 1SS6|A PF08060.8_NOSIC_seed 101 55 !Q:30,30|37,40|46,46|53,53 Q:0,29|31,36|41,45|47,52|54,54 HHHHHHHHHHHHHHHHHHHHHHHHHHHTTT?TTHHHH???-HHHHH-HHHHHT?S 3ID5|A PF08063.7_PADR1_seed 17 61 !Q:11,11|14,16|20,23|30,31|36,37|40,41|47,51|56,57|60,60 Q:0,10|12,13|17,19|24,29|32,35|38,39|42,46|52,55|58,59 HHHHHHHHHHH?EE???TTT??-?EEEETT--EEEE??EE--ETTEE?--??EESS??EE? 2RIQ|A PF08068.7_DKCLD_seed 16 61 !Q:0,1|5,5|13,13|18,26|28,31|35,36|51,51|55,55 Q:2,4|6,12|14,17|27,27|32,34|37,50|52,54|56,60 ??TTS?GGGTTGG-GSEE???-?????S????STT??HHHHHTTEEEEEEE?SSS?HHHHH 3HAY|A PF08069.7_Ribosomal_S13_N_seed 64 71 !Q:0,40|50,52|68,69 Q:41,49|53,67|70,70 ????????--?--?????????----?????????--????HHHHHHTTS??-SSHHHHHHHHHHHHH??H 2XZM|O PF08071.7_RS4NT_seed 34 39 !Q:2,6|12,12|16,18|22,23|26,30|35,35 Q:0,1|7,11|13,15|19,21|24,25|31,34|36,38 SS?????BTTSS?GGG???SSS-?SB?????SSSS?GGG 2XZM|W PF08075.6_NOPS_seed 11 53 !Q:1,1|6,8|14,16|19,19|22,24|34,34|38,39 Q:0,0|2,5|9,13|17,18|20,21|25,33|35,37|40,52 B?EEEE???EESSS???GG-GS???HHHHHHHTS?SEE??TTSHHHHHHHHHH 3SDE|A PF08078.7_PsaX_seed 2 37 !Q:0,12|36,36 Q:13,35 ---??????????HHHHHHHHHHHHHHHHHHHHHTS? 1JB0|X PF08079.7_Ribosomal_L30_N_seed 70 71 !Q:0,4|63,63|66,70 Q:5,62|64,65 ?????STTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?EE????? 3J39|F PF08084.6_PROCT_seed 32 135 !Q:0,0|20,20|29,31|33,37|41,41|44,45|52,52|61,62|71,71|74,74|77,77|81,84|87,90|95,98|101,101|105,105|111,119|124,124|128,134 Q:1,19|21,28|32,32|38,40|42,43|46,51|53,60|63,70|72,73|75,76|78,80|85,86|91,94|99,100|102,104|106,110|120,123|125,127 ?EEEEEEEETTEEEEEEEEE?HHHHHHHH---H???-?SSS?TT??GGGEEE?EEEEESSS??EEEEESSS?SB?TT?STT??--TT????EEES????TT?GGG?HHHHT?????----GGGG-GTT??????? 4ILG|C PF08086.6_Toxin_17_seed 4 41 !Q:0,3|9,11|15,16|30,30|37,37 Q:4,8|12,14|17,29|31,36|38,40 ????GGGTS???SEE??HHHHHHHHHHTSS?EEEESS?EEE 1NE5|A PF08088.7_Toxin_19_seed 8 44 !Q:0,6|9,11|13,13|20,21|31,32|37,37|39,42 Q:7,8|12,12|14,19|22,30|33,36|38,38|43,43 ???????SS???S?STTSSS--EEETTEEES??SSSS?S????T 2JRY|A PF08089.6_Toxin_20_seed 3 50 !Q:0,2|4,7|13,14|18,19|22,32|35,36|49,49 Q:3,3|8,12|15,17|20,21|33,34|37,48 ???S????STTTS?-SEE??SS----------?SS??SSEEEETTEEEE? 1I25|A PF08091.6_Toxin_21_seed 2 40 !Q:0,0|2,2|5,5|17,17|20,22|26,28|32,33|37,39 Q:1,1|3,4|6,16|18,19|23,25|29,31|34,36 ?B?TT?EESSGGGBTTS?EE???SSS?--SSS??EEE-?? 2M36|A PF08093.6_Toxin_23_seed 5 30 !Q:0,1|3,3|7,8|17,20|22,22|27,29 Q:2,2|4,6|9,16|21,21|23,26 ??B?SSS??SSTTSBSS??-?B?SSSB??? 1G9P|A PF08094.6_Toxin_24_seed 2 33 !Q:0,1|3,3|7,7|11,11|13,13|20,20|24,24|31,32 Q:2,2|4,6|8,10|12,12|14,19|21,23|25,30 ??B?TTS?SSS?B?TTEEEE?SSS?EEEETT?? 1EYO|A PF08095.6_Toxin_25_seed 2 22 !Q:0,2|13,13|21,21 Q:3,12|14,20 ???TTTHHHHHHS?TTHHHHH? 1HP9|A PF08098.6_ATX_III_seed 2 27 !Q:0,1|3,4|6,9|14,14|18,18|21,21|24,24 Q:2,2|5,5|10,13|15,17|19,20|22,23|25,26 ??S??S----TTTT?SSS?SS?SS?SS 1ANS|A PF08099.6_Toxin_27_seed 2 33 !Q:0,3|6,7|18,19|22,23|28,28|32,32 Q:4,5|8,17|20,21|24,27|29,31 ????SS??EESSGGGSTT??EE??SSSS?EEE? 1IE6|A PF08100.6_Dimerisation_seed 30 61 !Q:18,18|20,22|24,28|30,30|40,45 Q:0,17|19,19|23,23|29,29|31,39|46,60 HHHHHHHHTTHHHHHHTT?T---T---??B?HHHHHHTSS-?--??TTHHHHHHHHHHHHH 3TKY|A PF08113.6_CoxIIa_seed 2 34 !Q:0,4|33,33 Q:5,32 ?????HHHHHHHHHHHHHHHHHHHHHHHHHHHT? 4FA7|C PF08117.6_Toxin_30_seed 2 36 !Q:0,2|6,6|10,11|16,17|23,24|33,35 Q:3,5|7,9|12,15|18,22|25,32 ???SSB?TTS??TTTT??BSSTT??EETTTTEE--? 1I26|A PF08123.8_DOT1_seed 11 211 !Q:12,13|15,16|22,25|27,27|40,41|44,44|51,51|65,66|74,75|99,102|110,110|114,114|124,124|130,131|134,135|143,143|150,151|154,154|161,161|164,164|167,171|177,177|189,190|193,194|201,203 Q:0,11|14,14|17,21|26,26|28,39|42,43|45,50|52,64|67,73|76,98|103,109|111,113|115,123|125,129|132,133|136,142|144,149|152,153|155,160|162,163|165,166|172,176|178,188|191,192|195,200|204,210 HHHHTGGGGGGG?-S??SSGGG????B?HHHHHHHHHHTT??TT?EEEEES?TTSHHHHHHHHHH??SEEEEEE??HHHHHHHHHHHHHHHHHHHHTTB????EEEEESS?STT?HHHHHHGGG?SEEEE??TT??HHHHHHH-HHHHTT??TT?EEEESS?SS?TT??-??SSSTT?GGGGEEEEEEE??TT-?BTTBSS?-?EEEEEEE 4EKG|A PF08124.6_Lyase_8_N_seed 26 412 !Q:5,10|12,12|16,17|20,20|36,36|43,46|50,50|52,52|58,67|75,76|92,92|100,100|123,143|145,146|170,173|188,190|192,199|209,211|214,215|235,235|249,256|260,260|265,270|278,278|283,293|298,298|323,325|350,350|360,360|364,373|376,377|391,391|396,396|401,402 Q:0,4|11,11|13,15|18,19|21,35|37,42|47,49|51,51|53,57|68,74|77,91|93,99|101,122|144,144|147,169|174,187|191,191|200,208|212,213|216,234|236,248|257,259|261,264|271,277|279,282|294,297|299,322|326,349|351,359|361,363|374,375|378,390|392,395|397,400|403,411 HHHHH------T?GGG??TT?HHHHHHHHHHHHHHH-HHHHHS??--STT?S?SSGGG?--------?TTSTHHH--HHHHHHHHHHHHHHT?TTSTTTT?HHHHHHHHHHHHHHHHHTSSTT??-----------------??S-?HHHHHTHHHHHHHHHHHHTTTSS?---HHHHHHHHHHHHHH???T--------TEESTTSSS--?EE??HHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHGG--------GGS?BSSS------SEEBTTS?EEET-----------TTEE?TTTHHHHHHHHHHHHHHHHTTSSS???HHHHTHHHHHHHHTTGGGEETTEE?GGGSGGGGG?GGG?---------HH--HHHHHHHHHHHHH-HHTS?HHHH--HHHHHHHHH 2E24|A PF08125.8_Mannitol_dh_C_seed 16 261 !Q:2,6|11,17|31,32|35,35|39,39|41,42|48,50|53,59|65,65|70,71|98,99|126,133|135,136|150,150|153,155|183,183|185,187|205,205|209,209|211,215|225,229|234,234|246,246|257,257 Q:0,1|7,10|18,30|33,34|36,38|40,40|43,47|51,52|60,64|66,69|72,97|100,125|134,134|137,149|151,152|156,182|184,184|188,204|206,208|210,210|216,224|230,233|235,245|247,256|258,260 HH?????EEEE???????HHHHHHHHHHHSS??TT?EEE?S??EEEEE???SS????---GGGGT?EEES??HHHHHHHHHHTHHHHHHHHHHHHHTT??BHHHHTTSHHHHHHHHHHHHHTTGGG???----?S??HHHHHHHHHHHHT?TT???BHHHHHTTHHHHHHHHTHHHHHHHHHT-T???HHHHHHHHHHHHHTTSB?TTS?B?????TTHHHHHHH-----HHTS?TTHHHHHHHHT?HHHHTTTGGG?HHH 4IM7|A PF08126.6_Propeptide_C25_seed 4 223 !Q:0,7|10,14|18,18|31,34|36,36|47,48|55,55|58,58|60,63|68,70|78,79|81,82|99,99|101,105|107,107|109,111|113,113|118,118|123,123|125,133|138,139|141,141|144,145|150,152|166,167|192,196|199,199|202,212|222,222 Q:8,9|15,17|19,30|35,35|37,46|49,54|56,57|59,59|64,67|71,77|80,80|83,98|100,100|106,106|108,108|112,112|114,117|119,122|124,124|134,137|140,140|142,143|146,149|153,165|168,191|197,198|200,201|213,221 ????????TT----?EEE-EEETTEEEEEEE--??S?EEEEEEETTE--EEEEEE?TT?B????TTSB???BEEEEEE??S--SEEEEEEEEEEEEEEE?S?---?B?B???S?BTTS?GGGS?B------???GGGG??S?BS??SEEE???EEETTEEEEEEEE??EEEETTTTEEEEEEEEEEEEEEEE-----EE?SS???????????TTHHHHHHH? 4IEF|A PF08127.8_Propeptide_C1_seed 60 47 !Q:0,1|11,11|13,15|20,27|30,30|39,43|45,47 Q:2,10|12,12|16,19|28,29|31,38|44,44 ??HHHHHHHHH-H-??SEEE???--?-?SB?HHHHHHHS??-??S??- 3PBH|A PF08129.6_Antimicrobial17_seed 2 57 !Q:0,20|41,42|56,56 Q:21,40|43,55 -------------------??TTTHHHHSSSHHHHHHHHHT??HHHHHHHHHHHHH? 2JPL|A PF08131.6_Defensin_3_seed 2 39 !Q:0,3|10,10|17,17|20,21|23,23|26,26|28,28|37,38 Q:4,9|11,16|18,19|22,22|24,25|27,27|29,36 ????BTTTTT?EEEETT?SS??B?SS?B?SSTTEEEE?? 1ZUE|A PF08138.6_Sex_peptide_seed 5 63 !Q:0,22|24,26|28,35|37,37|42,42|48,49|52,54|57,57|60,62 Q:23,23|27,27|36,36|38,41|43,47|50,51|55,56|58,59 ---------------------??S???S???-----S?SSSS?STTSS??SS???TT?SS?-? 2LAQ|A PF08148.7_DSHCT_seed 102 245 !Q:0,0|4,7|10,11|18,24|38,41|44,45|53,91|96,102|119,119|121,123|128,130|134,138|141,143|145,145|150,151|156,162|165,174|177,181|198,215|224,224|233,234|237,245 Q:1,3|8,9|12,17|25,37|42,43|46,52|92,95|103,118|120,120|124,127|131,133|139,140|144,144|146,149|152,155|163,164|175,176|182,197|216,223|225,232|235,236 ?TTT???-SH--HHHHHH????---TTHHHHHHHHHHH-???SS??THHHHHT????????????---------????---------?????HHHH-------HHHHHHHHHHHHHHTT?S--?HHHH---HHH-----HH-??S?HHHH--HHHH???????GG----------GT?-???HHHHHHHHHHHHHHHS?????-----??--????HHHHHHHH-HHHHHHHH--HT????????- 4A4Z|A PF08152.7_GUCT_seed 19 112 !Q:0,4|6,7|24,24|26,26|28,29|44,44|46,48|54,57|60,60|64,65|84,87|89,94|96,96|101,111 Q:5,5|8,23|25,25|27,27|30,43|45,45|49,53|58,59|61,63|66,83|88,88|95,95|97,100 ????-S??SSTTSSSSSEEEEEEE?S-S??SSTHHHHHHHHHHS?S---TTTTS????EE?GGG--SEEEEEEEHHHHHHHTTS????S------S?EEEE??---?----- 2E29|A PF08169.6_RBB1NT_seed 7 100 !Q:0,4|14,17|19,19|22,22|25,25|33,34|37,37|40,43|46,46|55,56|61,61|67,69|74,74|81,81|94,97 Q:5,13|18,18|20,21|23,24|26,32|35,36|38,39|44,45|47,54|57,60|62,66|70,73|75,80|82,93|98,99 --???SSTTSEEEE----E?SS?SS?EEEEEEE??SS?SS????TT?EEEEESSS??EEEE?TTTEE???STTS?HHHHHH?HHHHHHHHHHHT????TT 2YRV|A PF08171.6_Mad3_BUB1_II_seed 8 99 !Q:0,29|33,39|45,45|56,64|71,73|78,98 Q:30,32|40,44|46,55|65,70|74,77 ?????????--------------???????EEE???????EEESS?HHHHSTTSSS------???HHHHHH---HHTT?------?????????-???? 2I3T|B PF08191.6_LRR_adjacent_seed 29 65 !Q:1,1|3,5|12,12|21,25|28,33|48,48|63,64 Q:0,0|2,2|6,11|13,20|26,27|34,47|49,62 S?B???SEEGGG?EEETTEEE?-?-?SS--?--?SEEEEEEEEEEEET-TEEEEEEEEEEEEB?? 2WQX|A PF08198.6_Thymopoietin_seed 7 49 !Q:0,3|5,5|10,10|23,26|29,30|47,48 Q:4,4|6,9|11,22|27,28|31,46 ????S?BEEE?HHHHHHHHHHTT????SS??EHHHHHHEEEEBBTTT?? 1GJJ|A PF08203.6_RNA_polI_A14_seed 17 101 !Q:1,1|9,10|13,14|31,63|82,100 Q:0,0|2,8|11,12|15,30|64,81 S?SEEEESS??EE??HHHHHHHHHHHHHHHH??-??????????????????????????????THHHHHHHHHHHHHHTTS?-------------????? 2RF4|B PF08204.6_V-set_CD47_seed 12 139 !Q:0,14|16,18|23,23|25,25|28,28|34,35|40,42|71,72|78,78|80,82|91,92|104,104|117,117|128,138 Q:15,15|19,22|24,24|26,27|29,33|36,39|43,70|73,77|79,79|83,90|93,103|105,116|118,127 ------------???B???SEEE-E?TT?SEEEE??BBSS???SSGGGEEEEEEESSSEEEEEETTTTEEE??GGGTT?B??-GGGGGGTB??EEEEHHHHHTT?EEEEEEEEETTE-EEEEEEEEEE??????????? 2JJT|C PF08205.7_C2-set_2_seed 33 107 !Q:5,7|14,18|20,20|28,30|37,38|49,50|53,54|67,67|71,72|82,84|88,88|91,92|99,99|105,106 Q:0,4|8,13|19,19|21,27|31,36|39,48|51,52|55,66|68,70|73,81|85,87|89,90|93,98|100,104 EEEES??-SEEETT-----S?EEEEEEE---EEEEBS??EEEEEETTEE??TT--SSSEEEEEEEEE?TTT??EEEEEEEEE???TTS?SS??EEEEEE?SSTTS?? 1DN2|A PF08206.6_OB_RNB_seed 48 66 !Q:4,11|19,24|31,31|38,39|42,42|50,55|65,65 Q:0,3|12,18|25,30|32,37|40,41|43,49|56,64 EEEE??-????-EEEEEET------TEEEEE?HHHHTT??TT?EEEEEEE??????EEEEEEEEE? 1A62|A PF08207.7_EFP_N_seed 222 84 !Q:4,5|8,8|13,13|21,41|45,45|49,56|68,70|77,77|79,79|81,81 Q:0,3|6,7|9,12|14,20|42,44|46,48|57,67|71,76|78,78|80,80|82,83 EGGG??TT?EEEE-TTEEEEE---------------------EEE-EEE?-??????EEEEEEEETTT?-?EEEEEE?T-T?EE 3OYY|A PF08208.6_RNA_polI_A34_seed 25 271 !Q:0,4|16,16|20,21|26,27|29,37|40,43|57,75|79,79|81,81|85,85|89,101|110,124|129,138|141,147|150,151|154,270 Q:5,15|17,19|22,25|28,28|38,39|44,56|76,78|80,80|82,84|86,88|102,109|125,128|139,140|148,149|152,153 ?????EEEEEEEESSS?TTT?-SEEE??S---------SS?-??EEETTEEEEEEEE??????---??????????EEE?S?SSS?BEE-????????????SEEEEEEE????????-------HHHH??????????SS???????TT??TT????-----------------------???????--????????????????????????????------??????????---------------------------------???? 3NFF|B PF08209.6_Sgf11_seed 33 34 !Q:2,2|6,6|10,11|28,33 Q:0,1|3,5|7,9|12,27 GG?EEE?TTT??EEEGGGHHHHHHHHTT-????? 3MHH|C PF08210.6_APOBEC_N_seed 22 307 !Q:5,7|10,48|76,76|80,81|84,84|99,115|118,118|129,131|134,151|163,168|179,182|187,187|190,207|219,221|228,229|232,234|245,248|251,287|306,306 Q:0,4|8,9|49,75|77,79|82,83|85,98|116,117|119,128|132,133|152,162|169,178|183,186|188,189|208,218|222,227|230,231|235,244|249,250|288,305 HHHHH???TT??----------------------------------???EEEEEEEEEEEETTEEEEEEEEEEEEE?SSS--TT?SHHHHHHHHHHHHT?---------------?SS?EEEEEEEESS???HH------------------HHHHHHHHHHT?-----TTEEEEEEES--??TTTT?HH------------------HHHHHHHHHHT---TEEEEE??HH---HHHHHHHHSB?--?TT-------------------------------??????TTHHHHHHHHHHHHHHHH? 3VM8|A PF08211.6_dCMP_cyt_deam_2_seed 18 146 !Q:7,9|15,23|27,36|40,54|66,66|68,68|72,74|85,85|91,91|93,94|100,100|102,102|115,116|118,119|131,131|134,134|137,138|146,146 Q:0,6|10,14|24,26|37,39|55,65|67,67|69,71|75,84|86,90|92,92|95,99|101,101|103,114|117,117|120,130|132,133|135,136|139,145 HHHHSTT???GGGGT?-----???BTS????????-?SSH---------------HHHHHHHHHHH?B?TTT???EEEEEEETTS?EEEEE?B??TTSTT?B?HHHHHHHHHHHT--T??GGGEEEEEEEE?TT?SS??HHHHHHH- 1CTU|A PF08212.7_Lipocalin_2_seed 19 159 !Q:0,2|7,7|16,18|22,22|25,25|35,35|39,40|50,51|55,56|71,71|74,74|76,76|85,92|107,107|115,115|120,120|130,131|146,146|148,149|153,153|156,158 Q:3,6|8,15|19,21|23,24|26,34|36,38|41,49|52,54|57,70|72,73|75,75|77,84|93,106|108,114|116,119|121,129|132,145|147,147|150,152|154,155 ??-HHHH?EEEEEEEE???GGG-TT?EEEEEEEEE?TTS-?EEEEEEEEE--TTT--TEEEEEEEEEEESS?TT-S?EEEEEEET--------TEEEEEEEEEEBTT-SSEEEEE?SSTT?EEEEESSSS??HHHHHHHHHHHHHT-T??GGG?EE??? 1KT7|A PF08214.6_KAT11_seed 34 607 !Q:8,9|14,14|23,25|28,28|30,31|34,36|39,39|41,46|63,88|103,106|109,111|113,113|126,126|128,129|132,145|161,161|168,168|171,171|174,185|188,189|202,217|224,237|240,244|247,247|256,258|260,260|264,266|272,272|275,285|303,329|333,334|337,338|344,344|347,348|359,359|362,362|364,370|374,374|377,378|382,425|432,433|436,436|449,468|470,470|474,476|494,496|504,504|508,518|522,522|524,534|549,549|552,553|564,564|571,576|583,588|593,594|596,606 Q:0,7|10,13|15,22|26,27|29,29|32,33|37,38|40,40|47,62|89,102|107,108|112,112|114,125|127,127|130,131|146,160|162,167|169,170|172,173|186,187|190,201|218,223|238,239|245,246|248,255|259,259|261,263|267,271|273,274|286,302|330,332|335,336|339,343|345,346|349,358|360,361|363,363|371,373|375,376|379,381|426,431|434,435|437,448|469,469|471,473|477,493|497,503|505,507|519,521|523,523|535,548|550,551|554,563|565,570|577,582|589,592|595,595 HHHHHHTT--SBTT?EEEEEEEE???EE-E??SB???SS?S?---??SEEEEEEEEEEEESSS-------------------------?EEEEEEEEEEEEES----SS---S?EEEEEEEEEEEE?S??SS-----------???HHHHHHHHHHHHHHS?TTGGGS?BB?SS????????????SS??HHHHHHHHHHHH----------------HHSSSS??????????????SB?????SS?EEEEEEEE???S?SSS---TTGGG?TT------?????HHHHHHHHHHHHHHHHH---------------------------HTB?-TT-?EEEEE?TT??HHHHHHHHTT?SS-S?-----?EES?TT??SSS-----------------------------------??-------GGGTSB??TT?HHHHHHHHHHHT--------------------T?TTT?-?HHHHHHHHHSTTTTTTS???EEEEEEE?BSS??----?????TTT?B??---------SSHHHHHHHHHHHH-TS??SSHHHHHHHH-HHHHHH------HHHHHS??---?EEEE??B??????????? 3Q35|A PF08216.6_CTNNBL_seed 12 111 !Q:13,26|51,51|54,54|78,78|100,100 Q:0,12|27,50|52,53|55,77|79,99|101,110 SSTTTHHHHHHHT??????????????HHHHHHHHHHHHHHHHHHHHHHHH?TT?GGGTHHHHHHHHHHHHHGGGGGG?GGGHHHHHHTTHHHHHHHGGG?SSHHHHHHHH 4HM9|A PF08218.6_Citrate_ly_lig_seed 14 191 !Q:0,8|10,11|33,39|41,41|56,56|64,65|67,67|73,80|84,85|87,88|91,97|102,102|105,106|113,121|125,129|135,135|138,143|151,155|161,162|174,178|183,183|185,188 Q:9,9|12,32|40,40|42,55|57,63|66,66|68,72|81,83|86,86|89,90|98,101|103,104|107,112|122,124|130,134|136,137|144,150|156,160|163,173|179,182|184,184|189,190 ---------T??HHHHHHHHHHGGGSSEEEEEE???????S?HHHHHHHHHHHTTT?TTEEEEE??S?HHHHH--------HHH--T??EE-------EEEE?TT??HHHHHH---------HHH-----HHHHH?TT------SEEEEEE??---TTTTT??HHHHHHHHHTT--???TTTS?H----HH 3NBK|A PF08221.6_HTH_9_seed 18 64 !Q:11,11|25,25|38,41 Q:0,10|12,24|26,37|42,63 HHHHHHHHHHH?HHHHHHHHHHHHS?SEEHHHHHHHHT--??HHHHHHHHHHHHHTTSEEEEEE 2XV4|S PF08222.6_HTH_CodY_seed 3 61 !Q:5,5|15,16|38,38|42,42|48,49|60,60 Q:0,4|6,14|17,37|39,41|43,47|50,59 TEEEE?HHHHHHHHT??HHHHHHHHHHHHHTTSEEEEE?SSS?EEEEE??HHHHHHHHHT? 2B0L|A PF08223.6_PaaX_C_seed 63 201 !Q:0,10|12,12|19,20|22,23|41,41|56,60|62,69|76,76|82,92|104,104|119,145|149,150|169,173|177,178|181,182 Q:11,11|13,18|21,21|24,40|42,55|61,61|70,75|77,81|93,103|105,118|146,148|151,168|174,176|179,180|183,200 ???-------?S?EEEEEE-?S??SSHHHHHHHHHHHHHTT?EEEETTEEEEETTS?????S--------SGGGSE-EEEEE?---------?SSHHHHHHHHS?HHHHHHHHHHHHHH---------------------------HHH??SHHHHHHHHHHHHHHHTT?????GGG??TT??HHHHHHHHHHHHHHHHHH 3KFW|X PF08234.7_Spindle_Spc25_seed 58 88 !Q:0,82 Q:83,87 ????????--????????????????--??????-???-?????????????---???????????----?????????????HHHHT 3VZA|A PF08236.6_SRI_seed 25 108 !Q:12,13|31,31|36,38|60,66|69,74|78,78|80,81|100,100|103,104 Q:0,11|14,30|32,35|39,59|67,68|75,77|79,79|82,99|101,102|105,107 HHHHHHHHHHHH--HHHHHHHHHHTTTSSTT?SSSB???HHHHHHHHHHHHHHHHHHHHH-------HH?----?GGG?S??HHHHHHHHHHHHHHHTTT?SB??GGG 2A7O|A PF08238.7_Sel1_seed 594 63 !Q:8,15|21,21|23,29|32,32|34,44|48,49|62,62 Q:0,7|16,20|22,22|30,31|33,33|45,47|50,61 HHHHHHHH--------HHHHH?B-------TT-B??----?----HHH--HHHHHHHHHHTT? 1OUV|A PF08239.6_SH3_3_seed 263 125 !Q:3,4|8,9|13,13|17,19|21,23|28,34|36,36|40,42|47,50|53,54|59,74|76,77|81,100|106,106|108,111|115,119 Q:0,2|5,7|10,12|14,16|20,20|24,27|35,35|37,39|43,46|51,52|55,58|75,75|78,80|101,105|107,107|112,114|120,124 SEE--EEE--SSS-STT---T?--EEEE-------E-ETT--?EEEE----EE--EETT----------------E--EEE--------------------EETTE-E----EEE--?--SSSEE 2CT4|A PF08240.7_ADH_N_seed 92 209 !Q:13,13|18,19|25,37|41,43|46,52|54,56|66,67|69,70|73,74|76,81|83,83|86,86|91,93|98,107|110,123|130,130|132,132|134,134|137,162|165,165|172,181|183,184|190,190|195,201|205,205|208,208 Q:0,12|14,17|20,24|38,40|44,45|53,53|57,65|68,68|71,72|75,75|82,82|84,85|87,90|94,97|108,109|124,129|131,131|133,133|135,136|163,164|166,171|182,182|185,189|191,194|202,204|206,207 TTEEEEEEEEEEE?HHHH--HHHHT?------------SSS???SS-------B???SSEEEEEEE--E?-TT??S------S?TT?EEEE--?SEEE??--------SS--------------SHHHHH-T?G-GG?-------------------------TT?EEBTTT----------B??SSBSE-EEEE-------TTT?EE? 3QWA|A PF08241.7_Methyltransf_11_seed 172 163 !Q:4,7|9,9|21,28|30,31|39,39|42,48|52,57|68,68|71,84|91,99|103,106|108,109|112,114|117,117|120,122|127,127|129,130|134,140|142,142 Q:0,3|8,8|10,20|29,29|32,38|40,41|49,51|58,67|69,70|85,90|100,102|107,107|110,111|115,116|118,119|123,126|128,128|131,133|141,141|143,162 EEES---?T-TSHHHHHHHHH--------S??EEEEEES?HH-------HHH------HHHHHHHHTT?TT--------------TEEEEE??-------TTS?--?S?-TT--?EE-EE---EEES?T--TTS-------S?HHHHHHHHHTTEEEEEEEEE 3BKX|A PF08242.7_Methyltransf_12_seed 108 168 !Q:3,4|17,35|41,41|46,46|51,54|64,64|72,73|77,79|81,112|116,119|122,124|127,127|129,129|135,140|147,147|152,153|157,157|163,163 Q:0,2|5,16|36,40|42,45|47,50|55,63|65,71|74,76|80,80|113,115|120,121|125,126|128,128|130,134|141,146|148,151|154,156|158,162|164,167 EEE??TTSHHHHHHGGG-------------------EEEEE-EEES?HHHH----HHHHHHTTT?SSEEEEE??TTT???S------------------------------??EEE----EE---EE-S?GGGSS------SHHHHH-HHHH--HHH-HTEEE-EEEE 1BHJ|A PF08244.7_Glyco_hydro_32C_seed 178 197 !Q:4,4|11,12|15,22|31,31|35,39|51,53|59,59|69,76|82,83|92,92|96,96|98,100|104,113|118,122|124,126|130,177|197,197 Q:0,3|5,10|13,14|23,30|32,34|40,50|54,58|60,68|77,81|84,91|93,95|97,97|101,103|114,117|123,123|127,129|178,196 EEES?GGGSEE??TT-----???HHHHHHHS?TTS?---?SEEEEEEEEEE?--TTSSS?EEEEEEEEE?-------SSSSS?-EEEEEEEE?TTS?S--?SSB------????EEEE-----E???TTS?-----------------------------------------------EEEEEEEETTEEEEEETTT- 3PIJ|A PF08245.7_Mur_ligase_M_seed 92 309 !Q:5,5|18,19|24,27|29,29|32,32|35,35|38,38|41,48|50,51|54,55|69,72|75,75|82,83|90,91|97,106|111,112|115,118|124,126|128,128|134,134|144,144|152,157|166,169|173,185|187,187|190,190|193,193|202,209|214,217|219,220|223,224|227,262|264,264|267,267|270,271|274,277|280,283|286,291|293,295 Q:0,4|6,17|20,23|28,28|30,31|33,34|36,37|39,40|49,49|52,53|56,68|73,74|76,81|84,89|92,96|107,110|113,114|119,123|127,127|129,133|135,143|145,151|158,165|170,172|186,186|188,189|191,192|194,201|210,213|218,218|221,222|225,226|263,263|265,266|268,269|272,273|278,279|284,285|292,292|296,308 EESSS?HHHHHHHHHHHH--HTTS-???E-EE?SS?EE?SS?----???S??SS??HHHHHHHHHHHHH----TT?SEEEEE??TTHHHH--TTTSS--------??EEEE--EE????SSSSS--?S-SSHHH-HHHHHHGGG-TTEEEEE------EEEEEGGG----TTT?-----------?S?SE-EE-EEESSTTS--------SEEE?-??B??TT??EE------------------------------------E-EE?SS??EE----EE?---SS??----T---THHHHHHHHHHHH 3PYZ|A PF08246.7_Inhibitor_I29_seed 95 140 !Q:9,28|34,37|43,43|58,68|71,72|74,80|82,84|87,127|129,129|135,135 Q:0,8|29,33|38,42|44,57|69,70|73,73|81,81|85,86|128,128|130,134|136,139 HHHHHHHTT??--?---------------SSHHH----HHHHH-HHHHHHHHHHHHHT-----------TS??S-------E---EE----------------------------------------?S?TTTTS?HHHH 3QT4|A PF08249.6_Mastoparan_seed 5 14 !Q:0,1|13,13 Q:2,12 ??HHHHHHHHHHH? 1D7N|A PF08252.6_Leader_CPA1_seed 3 24 !Q:0,9|23,23 Q:10,22 ??????????HHHHHHHHHHHHH? 2XL1|A PF08263.7_LRRNT_2_seed 101 62 !Q:0,0|16,29|35,36|39,46|48,48|53,54|61,61 Q:1,15|30,34|37,38|47,47|49,52|55,60 ?HHHHHHHHHHHHHTT--------??----GGGTT??TT--------S?TTTT-?STTEEE? 4HQ1|A PF08264.8_Anticodon_1_seed 171 275 !Q:20,20|22,22|24,24|36,38|44,44|54,63|65,69|73,78|105,127|131,131|133,138|140,140|142,143|146,150|152,161|164,169|175,217|222,224|226,229|236,239|242,252|259,268 Q:0,19|21,21|23,23|25,35|39,43|45,53|64,64|70,72|79,104|128,130|132,132|139,139|141,141|144,145|151,151|162,163|170,174|218,221|225,225|230,235|240,241|253,258|269,274 HHHHHHHHHHHHHHHHHHHH-T-T?HHHHHHHHTHH---HHHHH-HHHHHHTTT?-------??H-----HHH------HHHHHHHHHHHHHHTTTSHHHHHHHH-----------------------HHS-S??----S?G--GG-----S?-?--??-??SS??---?HHHHH-------------------------------------------HHHH---H----HHHHHH----HH-----------HHHHTS-????-----SBEEEE 2V0G|A PF08266.7_Cadherin_2_seed 77 84 !Q:0,3|7,7|10,11|14,14|25,26|35,35|39,39|44,44|49,49|60,62|67,67|70,70|73,74|76,77 Q:4,6|8,9|12,13|15,24|27,34|36,38|40,43|45,48|50,59|63,66|68,69|71,72|75,75|78,83 ????EEE?SS??TT?EEEESTTTTT??HHHHHHTT?EEE?SSSS?SEEE?SSSSEEEESS???STTT?TT?SS??B??EEEETT 1WUZ|A PF08267.7_Meth_synt_1_seed 56 383 !Q:0,0|3,3|5,9|11,11|14,14|29,32|56,56|59,63|67,69|72,72|83,85|89,95|99,102|112,117|121,127|131,131|136,136|140,141|144,144|147,155|165,165|170,178|184,184|192,192|194,197|199,199|202,203|206,207|211,227|248,250|256,256|262,266|282,288|292,292|300,301|304,306|314,315|318,318|321,322|331,332|342,347|350,350|358,358|362,362|364,366|381,382 Q:1,2|4,4|10,10|12,13|15,28|33,55|57,58|64,66|70,71|73,82|86,88|96,98|103,111|118,120|128,130|132,135|137,139|142,143|145,146|156,164|166,169|179,183|185,191|193,193|198,198|200,201|204,205|208,210|228,247|251,255|257,261|267,281|289,291|293,299|302,303|307,313|316,317|319,320|323,330|333,341|348,349|351,357|359,361|363,363|367,380 ?BB?S?-???S?TT?HHHHHHHHHHHTSS?---HHHHHHHHHHHHHHHHHHHHHTT?SB----?EES???SS?HHHHHHHHTT???GGG?----??SSS--??HHHHHHHHH??----SSS---????EEE?TTSS?EEE??EE?TT??????-??HHHHHHHHH-HHTT-?-----??EEEEE?HHHHHHT?E----E?TT??TT??GGG-----------------GHHHHHHHHHHHHHHHHHTT??-EEEEE?GGGGS??--?HHHHHHHHHHHHHST-------TTT?SSEEEEE??SS???HHHHHHH--TT?TT??EEEEESSS-?TTHHHHHHH-???--SS?EEEEEEE?SSS?B???HHHHHHHHHHHHHH?? 3PPH|A PF08269.6_Cache_2_seed 34 111 !Q:29,29|33,37|48,61|64,65|67,67|72,73|77,77|88,88|94,94|96,96|99,100|102,102|105,106 Q:0,28|30,32|38,47|62,63|66,66|68,71|74,76|78,87|89,93|95,95|97,98|101,101|103,104|107,110 HHHHHHHHHHHHHHHHHHHHHHTHHHHHT?STT-----TTHHHHHHHH--------------HH??S-BTTB??EEE?TTSBEEEESS?GGGTT?B?TT-?B?TT??BHHH 4EXO|A PF08271.7_TF_Zn_Ribbon_seed 71 54 !Q:0,0|2,2|7,11|13,17|21,22|29,29|35,37|39,47|52,53 Q:1,1|3,6|12,12|18,20|23,28|30,34|38,38|48,51 ?S?TTTS?-??-E-----EEE--TTTTEE-EESSS-??B?????????SSSS?? 1DL6|A PF08272.6_Topo_Zn_Ribbon_seed 19 43 !Q:0,2|19,21|25,29|33,33|36,36|38,42 Q:3,18|22,24|30,32|34,35|37,37 ???EEEEEETTTTEEEEEE??-TTS?????EEB?SS?B????? 1YUA|A PF08273.7_Prim_Zn_Ribbon_seed 18 56 !Q:4,5|9,10|13,13|20,32|34,34|41,44|47,55 Q:0,3|6,8|11,12|14,19|33,33|35,40|45,46 EEEE??SSS??SS?EEEETT-------------S?EEETTT--??EE----????? 1NUI|A PF08274.7_PhnA_Zn_Ribbon_seed 34 50 !Q:0,0|2,12|16,20|22,33|35,35|49,49 Q:1,1|13,15|21,21|34,34|36,48 ?S-----?---??TTT?????E------------E?SSSEEETTTTEEE? 2AKL|A PF08275.6_Toprim_N_seed 93 182 !Q:7,7|11,11|14,15|22,22|26,28|37,37|41,44|47,55|57,57|61,62|68,68|71,72|74,75|87,87|90,90|92,93|96,97|100,107|116,116|120,121|123,123|130,130|132,145|148,148|150,151|153,153|157,159|161,164|167,168|172,173|175,175 Q:0,6|8,10|12,13|16,21|23,25|29,36|38,40|45,46|56,56|58,60|63,67|69,70|73,73|76,86|88,89|91,91|94,95|98,99|108,115|117,119|122,122|124,129|131,131|146,147|149,149|152,152|154,156|160,160|165,166|169,171|174,174|176,181 HHHHHHH?STT-HH--HHHHHH-HTT-??HHHHHHHT?EEE?---SS---------S?HHH--HHHHH-TT??H--HHHHHTTSEEE?TT-T??EE--ES------??SEEEEEEE?TTS-?E-EEEEEE?S--------------SS?S--S-SEE---E????SS??TTT??B-THHHHH 4EDT|A PF08278.6_DnaG_DnaB_bind_seed 90 159 !Q:1,1|12,12|20,24|34,35|50,50|54,55|58,58|60,64|71,73|75,75|87,90|92,92|95,98|117,117|119,122|131,132|139,139|141,145|149,150 Q:0,0|2,11|13,19|25,33|36,49|51,53|56,57|59,59|65,70|74,74|76,86|91,91|93,94|99,116|118,118|123,130|133,138|140,140|146,148|151,158 H-HHHHHHHHHH?TTHHHHS?--??TTTHHHHST--THHHHHHHHHHHHH-STT??HH-H-----HHHHTT---T?TTHHHHHHHHS---?T-TT?--?SHHHHHHHHHHHHHHHHH-H----HHHHHHHH--HHHHTT-T?--??HHH--HHHHHHHH 2HAJ|A PF08279.7_HTH_11_seed 103 67 !Q:8,9|13,13|16,17|19,19|30,31|43,43|48,55|61,63 Q:0,7|10,12|14,15|18,18|20,29|32,42|44,47|56,60|64,66 HHHHHHHH--HHH?SS?-B?HHHHHHHHTS-?HHHHHHHHHHH-HHHT-----???EEETT---EEE 2OQG|A PF08280.6_HTH_Mga_seed 16 63 !Q:0,0|16,18|20,20|22,22|24,25|34,34|49,51 Q:1,15|19,19|21,21|23,23|26,33|35,48|52,62 ?HHHHHHHHHHHHHHH-??S?B?G--GGHHHHTS?HHHHHHHHHHHHTT-??TTEEEEEETTE 2WTE|A PF08281.7_Sigma70_r4_2_seed 141 59 !Q:11,11|25,27|36,40|43,43 Q:0,10|12,24|28,35|41,42|44,58 HHHHHHHHHTS?HHHHHHHHHHHTS???HHHHHHHT-----TS?HHHHHHHHHHHHHHH 2H27|A PF08282.7_Hydrolase_3_seed 69 357 !Q:3,3|9,9|11,25|29,33|46,53|56,56|62,62|65,67|77,77|81,82|88,88|93,95|102,103|109,110|113,113|116,122|138,145|152,154|162,162|164,186|188,188|200,200|205,205|207,207|213,213|216,216|218,218|221,225|228,229|237,238|251,259|271,272|278,279|289,290|295,296|305,305|317,320|326,326|330,330|340,341|343,345|349,349 Q:0,2|4,8|10,10|26,28|34,45|54,55|57,61|63,64|68,76|78,80|83,87|89,92|96,101|104,108|111,112|114,115|123,137|146,151|155,161|163,163|187,187|189,199|201,204|206,206|208,212|214,215|217,217|219,220|226,227|230,236|239,250|260,270|273,277|280,288|291,294|297,304|306,316|321,325|327,329|331,339|342,342|346,348|350,356 EEE?IIIII-S?--------------TTS?-??-HHHHHHHHHHHH--------TT?EEEEE?SS--?HHHHHHHHH-HTT--GGGTT?EEEE---GGGTEE--EETTT??EE-EE????---GGGHHHHHHHHHHTT-------?EEEEEE---TTEEEES?T-----------------------T?HHHHHHHHHHT?EEEE?S?HHHHS?SS?S?EE-----EE??HHHHHHH--HHHHHHHTTTSE---------EEEESSTTEEE--EEETT??HHHHHHHHH--HHHT??GGGEEEEE?SGGGHHHHHHS----SEEEE?TTS?HHHHHHSSE--E???GGG-THHHHHH 3N28|A PF08286.6_Spc24_seed 24 171 !Q:28,170 Q:0,27 HHHHHHHHHHHHHHHHHHHHHTHHHHTT?????????????????----------------??????-------???????????????????????------------------------------??????-?????????---????????????????????????? 3IZ0|D PF08291.6_Peptidase_M15_3_seed 19 144 !Q:2,3|8,8|11,11|14,15|20,22|31,33|50,62|66,69|78,79|82,82|88,93|98,99|103,104|114,116|120,120|125,125|127,127|132,132|134,137 Q:0,1|4,7|9,10|12,13|16,19|23,30|34,49|63,65|70,77|80,81|83,87|94,97|100,102|105,113|117,119|121,124|126,126|128,131|133,133|138,143 TT??TTTT?SS?SS??SSSS--?HHHHHHHH---HHHHHHHHHHHHHTTS---------????EEE????HHHHHHHT??TT?GGGGT-----?EEEE??TTT-?HHHHHHHGG---GTT?SEEE?T-TSTT?S----SSEEEE 3N1G|A PF08292.7_RNA_pol_Rbc25_seed 33 178 !Q:0,1|4,4|9,9|23,23|27,38|47,52|55,55|58,59|70,90|95,95|98,98|110,157|163,163|166,167|171,171|177,177 Q:2,3|5,8|10,22|24,26|39,46|53,54|56,57|60,69|91,94|96,97|99,109|158,162|164,165|168,170|172,176 ??TT?EEEE-EEEEEETTEEEEE?TTS???---------EEEETTTS?-----TT?EE--ETTTTEEEEE??----------------???EEEE?TT?EEEEEEEEEEE-?????????????????----------????????????????????SEEEE-EE??STT?EEGGG? 2B8K|G PF08294.6_TIM21_seed 13 159 !Q:0,36|52,52|61,63|68,71|76,76|80,80|83,83|87,90|96,96|100,100|111,113|116,116|126,127|130,132|135,135|142,143|146,146|150,151|156,157 Q:37,51|53,60|64,67|72,75|77,79|81,82|84,86|91,95|97,99|101,110|114,115|117,125|128,129|133,134|136,141|144,145|147,149|152,155|158,158 ----------------????----------------?HHHHHHHHHHHHHHH?HHHHHHTT???BTTB????EEEE?EEE?SS?EEE????EEEEE?TTS?EEEEEEEEEE?--SS?EEEEEEEEE??SS?--SS?EEEEEE--EE?TTS??EEEE??S 2CIU|A PF08299.6_Bac_DnaA_C_seed 14 70 !Q:0,0|14,15|22,25|44,46|57,58 Q:1,13|16,21|26,43|47,56|59,69 ?HHHHHHHHHHHTT??HHHHHS????HHHHHHHHHHHHHHHHHS???HHHHHHHTTS??HHHHHHHHHHH 1L8Q|A PF08300.8_HCV_NS5a_1a_seed 19 64 !Q:0,0|5,8|10,10|16,16|23,23|27,27|40,41|44,45|48,48|55,55|57,58|62,62 Q:1,4|9,9|11,15|17,22|24,26|28,39|42,43|46,47|49,54|56,56|59,61|63,63 ?TTTS????B?SEEES?EEEEEE?TTS?EEEEEEETTEEE--EE??TT?HHHHHT?B??STT?B 3FQQ|A PF08301.8_HCV_NS5a_1b_seed 20 103 !Q:2,2|6,7|9,10|44,45|48,50|55,56|64,65|68,74|76,76|79,79|92,92|94,94|96,102 Q:0,1|3,5|8,8|11,43|46,47|51,54|57,63|66,67|75,75|77,78|80,91|93,93|95,95 SS?EEE??S??SEEEEEEETTEEEEEEEETTEEEEEEESSTTEE??SS???GGGS--SEETTEE??SS???????B?SS?EEEETTEEEETT?B?S??????? 3FQQ|A PF08305.6_NPCBM_seed 43 192 !Q:0,4|9,11|15,18|22,25|27,27|31,32|37,37|39,44|48,48|53,53|55,58|75,76|83,83|86,86|89,89|99,99|102,104|109,111|119,121|125,126|132,139|145,146|150,150|154,159|162,163|171,171|174,174|176,177|180,180|190,191 Q:5,8|12,14|19,21|26,26|28,30|33,36|38,38|45,47|49,52|54,54|59,74|77,82|84,85|87,88|90,98|100,101|105,108|112,118|122,124|127,131|140,144|147,149|151,153|160,161|164,170|172,173|175,175|178,179|181,189 ??-??SEEG---GGS??--SEE----E?SSS??EETS?T------TSS?EEEE?T----TSSEEEESSEEEEESS--EEEEEE?TT?TT?SEEEEEEEE?GG---GTTS-??EEEEEEE---ETT--EEEEE???-----EETTS??EEE-EEE?-----TT??EEEEEEE?TT-S??TT?EEEEEEEEE?- 2YGM|A PF08306.6_Glyco_hydro_98M_seed 6 386 !Q:0,16|19,20|25,25|34,34|42,44|49,50|59,59|72,72|75,81|83,83|91,96|109,109|111,111|115,116|118,121|131,132|134,134|138,138|143,144|147,150|159,159|169,170|174,175|180,186|201,201|204,210|214,216|229,230|232,233|252,254|258,259|293,294|298,299|301,303|306,306|315,315|331,332|350,365|383,385 Q:17,18|21,24|26,33|35,41|45,48|51,58|60,71|73,74|82,82|84,90|97,108|110,110|112,114|117,117|122,130|133,133|135,137|139,142|145,146|151,158|160,168|171,173|176,179|187,200|202,203|211,213|217,228|231,231|234,251|255,257|260,292|295,297|300,300|304,305|307,314|316,330|333,349|366,382 ????????????---??SS??SSSS?EEEEEEEB?HHHHHTT???BTTS??HHHHHHHS?TTTGGGEEEEEE?TT-------S?SSTTHHH------HHHHHHHHHHHT?B?TTT??B????EEEEEEEGG--G?TTT?GGGG??HH----HHHHHHHH?TTEEEEEEE??TTS??TTHH-------HHHHHHHHHHHHHT?EE-------EEE???GGGHHHHHTTTT--S??HHHHHHHHHGGGEEEEEE???GGG??HHHHHHHHHHHHHTTSSSEEEEEEETTHHHHTT??STT??S???SS?HHHHTTTS?HHHHHHHHHHHHTTT??EEEEESHHHHTEETTEE?---------------HHHHHTHHHHHHHHHHS??? 2WMJ|A PF08307.6_Glyco_hydro_98C_seed 3 277 !Q:7,8|13,18|23,23|27,27|36,42|44,44|48,51|53,54|57,57|59,60|63,63|67,67|75,75|79,80|84,84|87,87|93,95|105,108|125,127|131,133|140,140|145,145|153,153|156,156|163,163|166,166|173,178|184,185|187,189|195,195|214,219|229,236|248,248|273,276 Q:0,6|9,12|19,22|24,26|28,35|43,43|45,47|52,52|55,56|58,58|61,62|64,66|68,74|76,78|81,83|85,86|88,92|96,104|109,124|128,130|134,139|141,144|146,152|154,155|157,162|164,165|167,172|179,183|186,186|190,194|196,213|220,228|237,247|249,272 HHHHHHH??EEEE------GGGS?GGG?TTTTTTTT------?S?TTS???-S??TT?S??EE?TTS?HHHHHHH?TTS--EEE?TT?GGGGG---HHHHHHHHS????EESSEEEEETTEEEEE???SSS???EEEEEE?SSTT?SEEEEEE?TT?EEEEEE?SS?EEEEEE??????HHHHT??S???GGGTT-SHHHHHHHHHHHHTTTTS??????EEEEEEEET????????EEEESTTSEEE-EEEEETTTTEEEEEEEESSEEEEE?--- 2WMJ|A PF08311.7_Mad3_BUB1_I_seed 25 139 !Q:16,17|21,21|37,37|40,45|49,49|64,64|70,70|83,84|86,86|88,93|106,106|126,126 Q:0,15|18,20|22,36|38,39|46,48|50,63|65,69|71,82|85,85|87,87|94,105|107,125|127,138 HHHHHHHHHHHHHHGG--GSS?THHHHHHHHHHHHHH?TT---???TTT?HHHHHHHHHHHTTT?GGGTT?HHHHHHHHHHHT--T?S-----?HHHHHHHHHHTT?STTBHHHHHHHHHHHHHTT?HHHHHHHHHHHH 3ESL|A PF08312.7_cwf21_seed 76 89 !Q:25,26|29,68 Q:0,24|27,28|69,88 THHHHHHHHHHHHHHHHHHHHHHHH--HT-------------------------------------???HHHHHHHHHHHHHHHHHHTT 2E62|A PF08313.7_SCA7_seed 17 83 !Q:0,25|30,31|33,34|40,42|44,44|47,47|51,51|59,60|64,64|77,82 Q:26,29|32,32|35,39|43,43|45,46|48,50|52,58|61,63|65,76 --------???----???????????TTTS??S??TTTSS???S?TT?TTS?HHHHHHS??SSS?HHHHHHHHHHHH??--?? 2KKR|A PF08314.6_Sec39_seed 20 943 !Q:0,27|31,35|45,46|50,50|63,107|109,118|131,141|158,158|161,161|168,178|183,184|189,189|207,207|212,215|217,220|228,229|238,256|272,272|276,277|288,291|298,307|320,358|375,381|405,405|413,438|458,459|462,462|472,487|489,491|503,503|511,511|527,527|531,532|534,550|556,556|567,568|575,575|578,580|591,608|611,611|629,629|632,633|646,647|656,660|667,667|686,704|709,710|716,716|734,734|749,775|778,780|804,804|823,823|831,846|860,862|869,871|875,890|906,907|929,929|933,933|935,942 Q:28,30|36,44|47,49|51,62|108,108|119,130|142,157|159,160|162,167|179,182|185,188|190,206|208,211|216,216|221,227|230,237|257,271|273,275|278,287|292,297|308,319|359,374|382,404|406,412|439,457|460,461|463,471|488,488|492,502|504,510|512,526|528,530|533,533|551,555|557,566|569,574|576,577|581,590|609,610|612,628|630,631|634,645|648,655|661,666|668,685|705,708|711,715|717,733|735,748|776,777|781,803|805,822|824,830|847,859|863,868|872,874|891,905|908,928|930,932|934,934 ?????????????--?????????????SHH-----HHHHHHHHS?-TTS?GGGGTHHHHHHH?????????----????????????????????????????????G----------GGHHHHHHHTTT?-------???SHHHHHHHHHHHHHTT?TT?TTTTHH-----------HHHT??TTSS?HHHHHHHHHTHHHHHHH-HHHT----T????HHHHHHS-?HHHHHHHH??????????-----????HHHHHTHHHHHHHHT?HHH--HHHHHSSTTT????SHHHHH----------HHHHHHHHHHHT???????--------------------------------HHHHHHHHHHHHHHHH-------HHHHTSTTHHHHHHHHHHHHTTS?SEEEETT--------------------------TEEEEHHHHHHHHHHHHHT??SS?HHHHHHHHT----------------S?--HHHHHHHHHHH-HHHHHTT?SSHHHHHHHHHHTTT?TTS??S-----------------SSTTS?HHHHHHHHHH--HHHHTT?HH---HHHHHHHHTT?-----------------TT?HHHHHHHHHHHHHHHHH?SS??TTSHHHHHHHHH--HHHHHHHH-----HHHHTH-HHHHHHHHHHHHHHHTTS??--???????????????HHHH--HHTTT?THHHHHHHHHHSTTGGG?HHHHHHHHHHHHHH---------------------------TT???SSTHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHH?HHHHHHH----------------HHHHHHHHHHHHH???TTSGGG???HHH----------------HHHHHHHHHHHHHHS?-GGGHHHHHHHHHHHHHHHTTS?STT?S???????? 3K8P|D PF08321.7_PPP5_seed 10 98 !Q:14,25|30,32|37,40|43,44|46,48|53,54|67,67|69,73|92,92 Q:0,13|26,29|33,36|41,42|45,45|49,52|55,66|68,68|74,91|93,97 HHHHHHHHHHHHHH??????-?????STTT??-TTSS????TT??S???GGGS??HHHHHHHHHHHH-T?????HHHHHHHHHHHHHHHHTS?SEEEE 3H67|A PF08323.6_Glyco_transf_5_seed 179 399 !Q:1,3|8,8|10,10|12,21|25,26|28,28|44,45|50,53|56,57|63,65|72,80|83,83|89,91|93,94|98,100|108,108|111,136|143,143|146,146|149,153|156,162|165,165|170,170|173,178|180,180|182,182|191,193|206,206|209,216|219,224|228,229|240,240|249,249|251,258|267,276|279,281|284,287|292,292|295,296|298,301|303,308|312,312|322,348|355,355|361,361|380,386|390,390|392,392 Q:0,0|4,7|9,9|11,11|22,24|27,27|29,43|46,49|54,55|58,62|66,71|81,82|84,88|92,92|95,97|101,107|109,110|137,142|144,145|147,148|154,155|163,164|166,169|171,172|179,179|181,181|183,190|194,205|207,208|217,218|225,227|230,239|241,248|250,250|259,266|277,278|282,283|288,291|293,294|297,297|302,302|309,311|313,321|349,354|356,360|362,379|387,389|391,391|393,398 E---EEEE?S?B----------TTT--B?SSTHHHHHHHHHHHH--HHTT-?--EE--EEEEE??-HHHHTT?--------TT?EEEEE---E??TTS?--EEEEEEE-ET--------------------------TEEEEE-EE?HH-----HH-?----?SS-BTTB?TT------S?B?TTHHHHHH---HHHHHHHHHHTT-SS--------TT?-?--?SEE--EEESGGGTTH-HHHHHHTT?S--------SEEEEEES?---------TT???EE?---GGGG-GT--S???-G------GGS-STTTTEETT---------------------------EEEHHH-HHHHH?SEEEESSHHHHHHTTSTT-------TST-T?HHHHHH 3FRO|A PF08324.6_PUL_seed 22 359 !Q:2,14|27,34|38,41|48,51|63,72|87,89|91,92|106,106|108,124|138,157|176,176|190,195|204,207|210,211|213,223|248,248|250,258|264,264|299,302|305,306|316,326|336,344 Q:0,1|15,26|35,37|42,47|52,62|73,86|90,90|93,105|107,107|125,137|158,175|177,189|196,203|208,209|212,212|224,247|249,249|259,263|265,298|303,304|307,315|327,335|345,358 SS?????????????HHHHHHHHHHHH--------HHH????HHHHHH----HHHHHTSGGGS----------HHHHHHHHHHHHHH?--S??HHHHHHHHHHGGG?S?----------------GGGGHHHHHHHTT?-------------------SSHHHHHHHHHHHHHHTT?TTTHHHHHTSHHH------HHHHHHHS????TT??H-----------HHHHHHHHHHHHHHHHHHHHHHHS?S--------?TTHHH-HHHHHHHHTTTTSHHHHTSHHHHHHHHHHHHHHH----HH?-HHHHHHHTT----------?HHHHHHHHH---------HTTSHHHHHHHHHH 3PSP|A PF08327.6_AHSA1_seed 114 207 !Q:2,2|12,12|19,19|23,28|31,31|39,43|46,47|49,50|56,58|61,62|65,66|74,84|98,108|118,133|142,143|147,148|157,164|178,188|198,198 Q:0,1|3,11|13,18|20,22|29,30|32,38|44,45|48,48|51,55|59,60|63,64|67,73|85,97|109,117|134,141|144,146|149,156|165,177|189,197|199,206 SS?HHHHHHHHH?HHHHTT-TSS-----?TT?EEEEEEE??---ST--T?-EEEEE---EE?-TT??EEEEEEE-----------EEEEETTTEEEEE-----------SSEEGGGEE????????????????EEEEEEEE-?SSS--EEEEEEEE-------?SSHHHHHHHHTTT-----------HHHHHHHHH-HHHHHHHH 2L8O|A PF08328.6_ASL_C_seed 107 127 !Q:0,0|4,5|39,39|50,50|64,69|73,73|86,87|89,93|102,103|107,110|120,121|125,126 Q:1,3|6,38|40,49|51,63|70,72|74,85|88,88|94,101|104,106|111,119|122,124 ?STT??THHHHHHTTHHHHHHHHHHHHHHHHHHHHTEEE?HHHHHHHHTT?GGGGHHHHHHHHH------HTT?SSHHHHHHHHHT--T?-???HHHHHHHH--HTS?-??HHHHHHHHT??TTT?? 3GZH|A PF08329.5_ChitinaseA_N_seed 43 170 !Q:0,6|9,15|17,20|25,29|33,33|35,36|38,40|49,50|61,62|65,67|79,84|87,90|94,95|102,103|108,108|110,110|125,128|132,135|142,142|145,145|149,159|162,168 Q:7,8|16,16|21,24|30,32|34,34|37,37|41,48|51,60|63,64|68,78|85,86|91,93|96,101|104,107|109,109|111,124|129,131|136,141|143,144|146,148|160,161|169,169 ???????EE?------S??-?EEES-----EEE?T--T??-SHHHHEEE-?SSEEEEEEEE??SS???SEEEEEETTEE------EE----EEE??SSEEEE--EEEE?S?EEEEEEEEEEETTE----EEE??-?EEEEEE?TT?TTS??-???--???TT???????S 3ARO|A PF08332.5_CaMKII_AD_seed 7 128 !Q:19,19|35,35|41,42|56,63|76,76|93,93|97,97|125,127 Q:0,18|20,34|36,40|43,55|64,75|77,92|94,96|98,124 HHHHHHHHHHHHHHHHHHT?HHHHHHHEEEEEEEE?GGGTT??EESSHHHHHHHHH????????EEEEEEEEEEEE?STTEEEEEEEEEEEEE?TTS?EEEEEEEEEEEEEEETTEEEEEEEEEE??? 3F7S|A PF08334.6_T2SG_seed 175 143 !Q:0,10|14,17|20,22|37,37|45,45|50,52|56,56|64,65|68,70|73,75|80,83|85,89|93,98|102,110|112,113|115,115|117,117|119,119|124,125|129,131|138,138|142,142 Q:11,13|18,19|23,36|38,44|46,49|53,55|57,63|66,67|71,72|76,79|84,84|90,92|99,101|111,111|114,114|116,116|118,118|120,123|126,128|132,137|139,141 --??-------STT----HH---HHHHHHHHHHHHHH-HHHHHHH-HTSS???TTH-HHHHHHS??SS???SS???STTT?--?S??-??STT??---?EEE--???----S--S-S-S?EEEE??TTS???SSSSSS?EEE? 3GN9|A PF08335.6_GlnD_UR_UTase_seed 122 224 !Q:10,17|22,32|34,47|74,76|80,81|95,99|103,103|106,107|127,127|133,136|138,142|144,147|158,158|160,163|165,195|197,197|201,203 Q:0,9|18,21|33,33|48,73|77,79|82,94|100,102|104,105|108,126|128,132|137,137|143,143|148,157|159,159|164,164|196,196|198,200|204,223 HHHHHHHHHH--------HHHH----------?S??------------BTTTSTTSHHHHHHHHHHHHHHHTTT?--GGG??SSHHHHHHHHHHT-----TSS?HH--HHHHHHHHHHHHHHHHHHH-HHHHT????B??--?S----HHHHHHHHHH-T----T-----------------?-------------S?HHH---HHHHHHHHHHHHHHHHHHTT 1V4A|A PF08336.6_P4Ha_N_seed 57 149 !Q:0,1|50,52|78,79|85,89|92,93|104,107|110,112|115,116|134,135|143,148 Q:2,49|53,77|80,84|90,91|94,103|108,109|113,114|117,133|136,142 ??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--?HHHHTTSTHHHHHHHHHHHTHHHHH--HHHHH??-??HH--HHHHHHHHGG----GS-??HH--HHHHHHHHHHHHHHHTT??HHHHHTT?-???? 2YQ8|A PF08337.7_Plexin_cytopl_seed 11 648 !Q:0,3|5,6|17,43|46,47|49,49|52,64|98,98|140,141|149,151|192,192|194,194|198,199|203,203|210,217|223,231|233,236|239,240|243,252|261,262|276,277|281,281|286,287|306,306|308,308|313,315|319,321|323,325|330,332|335,335|342,411|413,413|415,459|484,484|491,493|512,514|537,537|544,547|566,566|569,577|605,608|628,628 Q:4,4|7,16|44,45|48,48|50,51|65,97|99,139|142,148|152,191|193,193|195,197|200,202|204,209|218,222|232,232|237,238|241,242|253,260|263,275|278,280|282,285|288,305|307,307|309,312|316,318|322,322|326,329|333,334|336,341|412,412|414,414|460,483|485,490|494,511|515,536|538,543|548,565|567,568|578,604|609,627|629,647 ????B??HHHHHHHHHS---------------------------TT??S?SS??????------?HHHHHHHHHHHHHHSSHHHHHHHHHHHHHSSSS?HHHHHHHHHHHHTTGGGGHHHHHHHHHHHHHHHHHHHHHTT??GGGSSSS???HHHHHHHHHHHHHTTTHHHHTTHHHHHHHHHHHHHHHTTS?B?TTT??BTT?SSSSSB????????EEEEE---------E??--TT??SS??--------EEEEEESS??HHHHHHHHHHHHT--SSS?SSSS??STTEEEEEEETTTEEEEE?S-SSSS???SSS-??B???HHHH???TT?EEEEEE???--??????????????---??????????????????????????????--------------????B?S??????-??-----??????-----------------????????TTHHHHHHHHHSHHHHHHHHHHHS?SSBTTB???HHHHHHHHHHHHHHHTTT???HHHHHHHHHTTTTTTTHHHHHH?TTTTBS????HHHHHHHHHHHHHHHHHH?SS?????????HHHHHGGGTHHHHHHHHHHHHHHHHHS????HHHHHHHHHHHHHTTTTSS?HHHHHHHHHHHHTTTHHHH 3Q3J|A PF08338.6_DUF1731_seed 150 55 !Q:1,3|9,11|15,15|20,20|25,28|30,31|39,41|43,44 Q:0,0|4,8|12,14|16,19|21,24|29,29|32,38|42,42|45,54 B?--HHHHH---HHH?HHHH-HHHH????B??HHHHHTT???S??SHHHHHHHHH 4B4O|A PF08341.6_Fb_signal_seed 30 94 !Q:3,5|11,19|21,24|28,28|30,30|34,34|38,39|44,44|49,49|51,51|61,64|70,70|72,72|82,85|89,89|92,92 Q:0,2|6,10|20,20|25,27|29,29|31,33|35,37|40,43|45,48|50,50|52,60|65,69|71,71|73,81|86,88|90,91|93,93 ETT???BSSSS---------B????EEE-E?TTS?EEE--EEES?TTSB?S?EESSTTSSB--??BTTTB-S?EEEEEESSS---?GGG?SS?S 2XIC|A PF08343.5_RNR_N_seed 65 89 !Q:8,8|10,12|16,19|40,42|44,44|56,56|60,60|65,65|69,72|87,88 Q:0,7|9,9|13,15|20,39|43,43|45,55|57,59|61,64|66,68|73,86 HHHHHHGG-G???TTS???-THHHHHHHHHHHHHTHHHHB???S?HHHHHHHHHHT-TSB?HHHH-TTS---?HHHHHHHHHHHHHS?? 1PEQ|A PF08347.6_CTNNB1_binding_seed 18 325 !Q:0,14|16,16|19,54|66,324 Q:15,15|17,18|55,65 ?????---???????S?TT???????????????????????????????----?HHHHHGGGTTT??------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------??--------- 1JDH|B PF08351.6_DUF1726_seed 42 132 !Q:0,5|7,9|12,13|21,21|24,26|38,38|41,41|49,49|57,89|95,97|101,103|106,106|108,109|124,124 Q:6,6|10,11|14,20|22,23|27,37|39,40|42,48|50,56|90,94|98,100|104,105|107,107|110,123|125,131 -?????T---TT??BSSEEEE?SS???HHHHHHHHTTB?TT?EEEEEES?GGGTTTS--------------------------------?BGGGH---HHH-??SS?B??HHHHHHHHHHHTSS-SSSEEEE 2ZPA|A PF08352.7_oligo_HPY_seed 59 97 !Q:10,11|14,15|27,46|49,54|58,59|61,78|80,81|88,88|91,92|95,95|97,97 Q:0,9|12,13|16,26|47,48|55,57|60,60|79,79|82,87|89,90|93,94|96,96 EEEEEHHHHH--HS??SHHHHHHHHTT????????-------?????SS???--?SSS??S------------------S--STTTTT?TT??HH-H- 4FWI|B PF08354.5_DUF1729_seed 31 59 !Q:1,2|15,15|21,21|29,29|33,35|37,38|45,48|53,53 Q:0,0|3,14|16,20|22,28|30,32|36,36|39,44|49,52|54,58 E??SSTTHHHHHHSS?SHHHH?TTTSSTT?GGG???B??SSTTTT??--SSSB?HHHHH 2UVA|G PF08355.7_EF_assoc_1_seed 32 110 !Q:2,2|12,12|14,14|18,19|36,36|52,84|89,89|99,105|108,109 Q:0,1|3,11|13,13|15,17|20,35|37,51|85,88|90,98|106,107 SS?TTTTHHHHS?B?TTT??EEHHHHHHHHHHHHHH?HHHHHHHHHHTTHHH---------------------------------HHTS?GGGGEEEEE???????SS?? 4C0J|A PF08356.7_EF_assoc_2_seed 30 103 !Q:2,4|19,19|23,23|27,29|49,49|63,63|69,69|75,90|98,98 Q:0,1|5,18|20,22|24,26|30,48|50,62|64,68|70,74|91,97|99,102 SS???HHHHHHHHHHHHHH-STT?BSS---SSEEHHHHHHHHHHHTTTT?HHHHHHHHHHTTB?TTSSB?HHHHS??----------????TTEEEEE?HHHH 4C0J|A PF08357.6_SEFIR_seed 15 176 !Q:6,10|15,15|30,32|41,41|49,49|58,61|65,65|73,108|124,129|135,135|141,142|144,148|150,151|157,158|160,160 Q:0,5|11,14|16,29|33,40|42,48|50,57|62,64|66,72|109,123|130,134|136,140|143,143|149,149|152,156|159,159|161,175 EEEEEE???-?GGGH-HHHHHHHHHHHHTS--?EEEEEGGG?HHHHHHH?HHHHHHHH----HHH?SEEEEEE????????????????????????------------THHHHHHHHHGGGTT?-----SSSTT?EEEEE?-S?????S??GGGGG--S?EEETTTTHHHHHHHH 3VBC|A PF08359.6_TetR_C_4_seed 8 133 !Q:18,19|39,39|51,53|84,84|86,86|89,90|115,115|117,117|132,132 Q:0,17|20,38|40,50|54,83|85,85|87,88|91,114|116,116|118,131 HHHHHHHHHHHHHHHHTT??SHHHHHHHHHHHHHHHHHT?HHHHHHHHTTT???SHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?B?TT??HHHHHHHHHHHHHHHHHHHHHTTT?S?GGGGHHHHHHHHHH? 1VI0|A PF08360.6_TetR_C_5_seed 3 132 !Q:15,16|36,36|52,52|83,85|87,87|106,106|110,110|130,131 Q:0,14|17,35|37,51|53,82|86,86|88,105|107,109|111,129 HHHHHHHHHHHHGGG??SHHHHHHHHHHHHHHHHHT?TTHHHHHHHHTTTSS?TTHHHHHHHHHHHHHHHHHHHHHHHHTTTS???S?HHHHHHHHHHHHHHHHHT?TTS?HHHHHHHHHHHHHHHHHTT?? 3BTJ|A PF08361.6_TetR_C_2_seed 12 121 !Q:0,0|19,19|33,35|71,71|75,75|97,97|101,102 Q:1,18|20,32|36,70|72,74|76,96|98,100|103,120 ?HHHHHHHHHHHHHHHHHH?HHHHHHHHHHHTS???SSTHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSS?TTB?HHHHHHHHHHHHHHHHHHHHH?TTT??TTTTHHHHHHHHHHHHHH 3VIB|A PF08362.6_TetR_C_3_seed 16 144 !Q:14,15|19,19|38,38|53,53|85,86|88,89|117,118|141,143 Q:0,13|16,18|20,37|39,52|54,84|87,87|90,116|119,140 HHHHHHHHHHHHHH??TTS?HHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHTT?TTTHHHHHTHHHHHHHHHHHHHHHHHHTTSS-?S??HHHHHHHHHHHHHHHHHTHHHHHHHHS??TTSHHHHHHHHHHHHHHHHHHH??? 3LOC|A PF08363.5_GbpC_seed 15 368 !Q:6,7|13,13|15,18|20,20|23,23|25,27|30,30|37,37|43,43|66,68|72,73|75,75|79,79|88,89|100,100|109,111|119,119|122,122|130,131|134,134|138,141|155,155|158,160|164,166|178,178|183,185|188,188|190,190|193,193|209,209|211,212|216,218|224,227|229,229|232,239|247,247|251,252|255,255|259,259|263,263|272,272|275,276|284,284|287,287|290,292|297,300|304,310|317,317|323,323|327,327|342,342|347,349|352,353|356,357|359,359|365,366 Q:0,5|8,12|14,14|19,19|21,22|24,24|28,29|31,36|38,42|44,65|69,71|74,74|76,78|80,87|90,99|101,108|112,118|120,121|123,129|132,133|135,137|142,154|156,157|161,163|167,177|179,182|186,187|189,189|191,192|194,208|210,210|213,215|219,223|228,228|230,231|240,246|248,250|253,254|256,258|260,262|264,271|273,274|277,283|285,286|288,289|293,296|301,303|311,316|318,322|324,326|328,341|343,346|350,351|354,355|358,358|360,364|367,367 TTTTTS--TTSBS-S???-B?EE?S?-?TT?EEEEEE-SSEEE?HHHHHHHHHSGGGHHHHHTTEE--?GGG??G-GGG?SGGGEESS??EEETTSTTSS?EETTTBTS-??EEEEEEE?TT?EEEEEEE??SS?EET----TEEEEEEEEEEEE?TT???SSS--?EEEEEESSGGG?EEEE???SS?B-SS?EEEEEEEEEEEETTS?B??EEE---EEEEE????B?SS--------EEEEEES?SSE--EE?BTT?SEE-EETTEEEE?SS??SSTTSTT?SS?SS-??SSTT????SSS------?TTGGGG?EEEEE-EES?EEEEEEEEEGGGTS?GGGS???TT??TT??B?SEEEE??B 2WD6|A PF08367.6_M16C_assoc_seed 22 258 !Q:3,3|25,26|47,53|55,55|58,61|66,66|69,74|89,91|103,103|105,105|108,108|126,127|132,132|144,144|156,156|159,159|191,191|193,193|196,196|199,202 Q:0,2|4,24|27,46|54,54|56,57|62,65|67,68|75,88|92,102|104,104|106,107|109,125|128,131|133,143|145,155|157,158|160,190|192,192|194,195|197,198|203,257 EEE?TTHHHHHHHHHHHHHHHHHHT??HHHHHHHHHHHHHHHHHHHS??---??T-TS????GGGS?SS??????EEEETTTEEEEEEE???SSEEEEEEEEE?T-TS?GGGGGGHHHHHHHTTTS-?BTTB?HHHHHHHHHHH?SEEEEEEEEEE?SS?TTEEEEEEEEEEEEEGGGHHHHHHHHHHHHH?B?TT?HH----HHHHHHHHHHHHHHHTTTTTHHHHHHHHHHTTTSHHHHHHHHHHSHHHHHHHHHH 2FGE|A PF08369.5_PCP_red_seed 132 56 !Q:0,1|11,11|13,17|19,19|23,26|42,43|45,46|53,53 Q:2,10|12,12|18,18|20,22|27,41|44,44|47,52|54,55 ??HHHHHHHHT-S----?G-GGH----HHHHHHHHHHHHHSS??S??HHHHHH-HH 2L09|A PF08375.6_Rpn3_C_seed 24 73 !Q:0,72 Q: ????????????????????????????????????????????????????????-?????????????--? 4BGR|S PF08376.5_NIT_seed 118 348 !Q:12,22|30,33|37,42|44,44|46,48|50,54|78,85|91,92|95,105|120,120|129,133|137,138|140,140|145,145|151,151|168,170|204,208|210,213|232,232|239,240|242,242|254,261|264,266|277,287|289,303|311,311|317,317|322,326|333,333|340,341 Q:0,11|23,29|34,36|43,43|45,45|49,49|55,77|86,90|93,94|106,119|121,128|134,136|139,139|141,144|146,150|152,167|171,203|209,209|214,231|233,238|241,241|243,253|262,263|267,276|288,288|304,310|312,316|318,321|327,332|334,339|342,347 HHHHHHHHHHHH-----------HHHHHHH----HTT------S-S---S?----HHHHHHHHHHHHHHHHHHHHHHH--------HHHTT??HH-----------HHHHHHHHHHHGGG-HHHHHHHH-----HHT?-S?HHHH-HHHHH-HHHHHHHTHHHHHGGG???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----T??-?HHHHHHHHHHHHHHHHHH-HHHHHH--S?HHHHHHHHHHS-----???HH---HHHHHHHHHS-----------S??----------???TTHHHHH-HHHHH-HHHH-----HHHHHH-HHHHHH--HHHHHH 4AKK|A PF08386.5_Abhydrolase_4_seed 38 140 !Q:0,0|3,4|14,17|21,25|35,36|38,38|41,42|47,47|49,50|52,57|59,59|68,68|72,72|86,87|89,92|100,102|108,108|123,124|128,139 Q:1,2|5,13|18,20|26,34|37,37|39,40|43,46|48,48|51,51|58,58|60,67|69,71|73,85|88,88|93,99|103,107|109,122|125,127 ?HH--HHHHHHHHH----HHS?????HHHHHHHTS--S?SS??HHHH-T--T?---?-S?EEEEEETT?SSS?HHHHHHHHHHSTT--E----EEEEETT?-?TTHHH-HSHHHHHHHHHHHH--HTS??---------- 2WTN|A PF08389.7_Xpo1_seed 59 232 !Q:7,8|22,25|29,29|32,33|40,42|48,63|84,87|89,89|91,92|96,96|100,100|112,117|132,152|169,173|176,176|182,186|188,188|191,192|203,208|214,223 Q:0,6|9,21|26,28|30,31|34,39|43,47|64,83|88,88|90,90|93,95|97,99|101,111|118,131|153,168|174,175|177,181|187,187|189,190|193,202|209,213|224,231 THHHHHH--HHHHHHHHHHHHH----HHH?TT--HHHHHH---HHHHH-?--------------SHHHHHHHHHHHHHHHHHHT----S?B--TTB?HHH-HHHHHHHHHHT------HHHHHHHHHHHHHH???------------------HHHHHHHHHHHHTTTT-----TS?THHHH-----S-SS--HHHHHHHHTS------SSGGG----------HHHHHHHH 4HAV|C PF08391.5_Ly49_seed 27 141 !Q:0,126|128,128 Q:127,127|129,140 ------------------------???????????????-????-?-??????????????????????????????-------??????????????????????????-------------????E-EEEEEETEEEEE 3G8L|A PF08392.7_FAE1_CUT1_RppA_seed 37 324 !Q:9,13|35,37|41,41|44,45|49,57|59,77|80,82|90,91|111,114|116,121|123,125|128,128|130,130|140,142|145,145|156,157|160,160|168,168|186,186|188,188|190,190|192,192|209,210|222,222|231,231|233,234|241,241|243,258|266,268|271,271|280,282|300,313|317,319|323,323 Q:0,8|14,34|38,40|42,43|46,48|58,58|78,79|83,89|92,110|115,115|122,122|126,127|129,129|131,139|143,144|146,155|158,159|161,167|169,185|187,187|189,189|191,191|193,208|211,221|223,230|232,232|235,240|242,242|259,265|269,270|272,279|283,299|314,316|320,322 EEHHHHHHH-----HTTSTTTGGGHHHHHHHHHTT???EEE?SS-?GGG---------G-------------------GG???HHHHHHH--HHHHHHHHHHHHHHHHHHH----H------T-??GG-G?SEEEEEESS???SS?HHHHHHHHHT??TT?EEEEEES?GGGHHHHHHHHHHHHHH-H?T-T?EEEEEEEEEGGGGGGG??SHHHHHHHHHB?EEEEEEEE?T--TTHHHH-T?------------???EEEEEEE?--TT?GGGEEEEE?--TTHHHHHHHHHHHHHHH--------------HHH---TTT? 3OIT|A PF08393.8_DHC_N2_seed 94 541 !Q:0,26|33,35|37,37|40,89|96,99|114,114|116,116|121,133|135,139|141,143|146,146|152,152|156,163|165,175|178,181|188,188|190,190|192,192|194,195|228,234|236,236|244,247|249,253|259,261|283,289|294,296|302,302|334,343|363,363|370,370|374,374|383,385|388,388|425,425|434,435|440,440|443,443|452,452|454,454|457,458|463,463|467,467|469,475|481,481|484,484|486,487|494,494|502,507|510,511|513,515 Q:27,32|36,36|38,39|90,95|100,113|115,115|117,120|134,134|140,140|144,145|147,151|153,155|164,164|176,177|182,187|189,189|191,191|193,193|196,227|235,235|237,243|248,248|254,258|262,282|290,293|297,301|303,333|344,362|364,369|371,373|375,382|386,387|389,424|426,433|436,439|441,442|444,451|453,453|455,456|459,462|464,466|468,468|476,480|482,483|485,485|488,493|495,501|508,509|512,512|516,540 ---??????????????????????-?HHHHHH-??T-TT?---??????????---?-????????????---??-----------???HHHHHH----HHHHHHHHTHHHHH-T-TSTT?--------?---H-----H---HH-HHHHH-HTT----????T-----------TS--??HHHHHH-S?H-H--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH------?B?EEEEETT----T-----EEEEE?--HHHHHHHHHHHHHHHHHTTSS-------TTTT---GGGGH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH???--?-???TTTSHHHHHHHHHHHHHHH-HHHHHH-HHS?BHHHHTTS---TT-HHHHHHHHHHHHHHHHHHHHHHHHHHHHTSGGGGGS?HHHHHHHH--HGGG?GG-GTGGGGGG-T?SS??EEEE?TTS?E-------EEEEE?TT-S-?EEEEEE-EEESSSS----??HH--H---HHHHHHHHHHHHHHHHHHHHHHHHT 4AKH|A PF08397.6_IMD_seed 8 228 !Q:9,11|55,56|138,140|143,143|222,222|225,227 Q:0,8|12,54|57,137|141,142|144,221|223,224 HHHHHHTHH---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSSS-?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT---SS?TTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS?TT??? 1Y2O|A PF08402.5_TOBE_2_seed 128 115 !Q:3,3|7,7|10,28|31,32|34,38|40,40|44,47|57,57|65,65|68,68|71,71|74,74|77,79|85,97|100,100|106,107|111,111 Q:0,2|4,6|8,9|29,30|33,33|39,39|41,43|48,56|58,64|66,67|69,70|72,73|75,76|80,84|98,99|101,105|108,110|112,114 EEE?TTT?EE-------------------GG--G?----S-SEE----EEEEEEEEE?SSEEEEE-EE?TT?SS?EE---EEEES?------????--TT?EEEEE??GGG?EEE 1OXS|C PF08411.5_Exonuc_X-T_C_seed 74 340 !Q:9,10|12,15|19,20|25,25|29,29|32,32|45,45|48,48|60,61|67,73|75,75|85,88|92,93|95,96|98,101|110,112|121,121|123,132|137,141|144,146|148,149|163,167|170,170|182,191|193,199|203,203|207,212|224,225|228,228|235,236|238,241|258,258|262,263|274,281|287,287|291,296|311,316|320,320|322,323 Q:0,8|11,11|16,18|21,24|26,28|30,31|33,44|46,47|49,59|62,66|74,74|76,84|89,91|94,94|97,97|102,109|113,120|122,122|133,136|142,143|147,147|150,162|168,169|171,181|192,192|200,202|204,206|213,223|226,227|229,234|237,237|242,257|259,261|264,273|282,286|288,290|297,310|317,319|321,321|324,339 TSHHHHHTT??G----GGT??EEEE?TTT?GG-GTTEEEEEEEEE?SS?SSEEEEEESSS??HHHHH-------S?HHHHHHHHS??--TTT??S--S????EEEEETTS??-EEEEGGGS?H----------HHHH-----HH---T??HHHHHHHHHHHHH?----TH-HHHHHHHHTTS------??-?S?--????GGG?TTS-???-?HHHHHHHHHHH--HS?GGGTTT--S????SSTHHHHHHHHHHHHH?GGG??HHHHHHHHHH--------HHHHS?HHH------HHHHHHHHHHHHHH------HTT?H--HHHHHHHHHHHHHHHH 1FXX|A PF08414.5_NADPH_Ox_seed 28 111 !Q:0,4|7,7|24,33|45,45|47,48|63,66|68,68|85,87|92,92|105,107 Q:5,6|8,23|34,44|46,46|49,62|67,67|69,84|88,91|93,104|108,110 ----?HH-HHHHHHHHHHHHHHHH??--?-?---HHHHHHHHHHH?B--TTBEEGGGHHHHHT??--S?HHHHHHHHHHHHHHHT??-SSEE?HHHHHHHHHHHH???HHH 3A8R|A PF08416.8_PTB_seed 14 148 !Q:11,11|14,15|23,24|32,38|76,76|79,80|84,84|88,96|121,124|129,129|143,147 Q:0,10|12,13|16,22|25,31|39,75|77,78|81,83|85,87|97,120|125,128|130,142 EEEEEEEEEEE?TT??HHHHHHH--HHHHHHH???????EEEEEEEETTEEEEEEEETTEEEEEEEEGGGEEEEEE?TT??EEE?TTS--------?EEEEEEEEEEETTEEEEEEEEEEE--??BTTB?HHHHHHHHHHHHH????? 3D8D|A PF08421.6_Methyltransf_13_seed 27 66 !Q:0,0|4,5|7,7|19,19|22,23|25,25|27,28|31,31|33,35|45,46|50,51|57,59 Q:1,3|6,6|8,18|20,21|24,24|26,26|29,30|32,32|36,44|47,49|52,56|60,65 ?TTT??E-EEEEEEEEEEE?TT??B?T--TS?S???EEEEEEEEE--TTT??EEESS???HHHHSS 4E2Z|A PF08423.6_Rad51_seed 20 259 !Q:0,1|3,5|17,17|20,21|23,23|31,31|65,65|70,71|73,73|83,85|97,99|112,113|133,133|148,155|178,180|187,207|216,216|225,225|234,235|237,237|241,246|256,258 Q:2,2|6,16|18,19|22,22|24,30|32,64|66,69|72,72|74,82|86,96|100,111|114,132|134,147|156,177|181,186|208,215|217,224|226,233|236,236|238,240|247,255 ??S???HHHHHHHHHSS?EE??S?HHHHHHH-TSSEESSSEEEEEESTTSSHHHHHHHHTTTTTS?TTTT??S?EEEEEESSS???GGGGHHHHHHT???HHHHGGGEEEEE??STTTHHHHHHHTHHHHHHS?EEEEEEETGGGGGS????????THHHHHHHHHHHHHHHHHHHHH???EEEEEE????????-????-???????HHHHHHHH?SEEEEEEE?STTEEEEE??S?SSS??????EEEETTEEE??? 4B32|A PF08433.5_KTI12_seed 21 437 !Q:1,1|7,8|27,38|41,42|47,48|54,59|64,65|67,69|91,92|98,98|100,102|119,119|128,146|155,159|164,164|166,222|224,224|235,237|242,242|246,247|253,258|262,264|266,287|295,310|317,318|324,327|329,331|351,354|358,359|363,395|412,417|419,419|421,423 Q:0,0|2,6|9,26|39,40|43,46|49,53|60,63|66,66|70,90|93,97|99,99|103,118|120,127|147,154|160,163|165,165|223,223|225,234|238,241|243,245|248,252|259,261|265,265|288,294|311,316|319,323|328,328|332,350|355,357|360,362|396,411|418,418|420,420|424,436 E-EEEEE??TTSSHHHHHHHHHHHHHH------------TT??EEEE?-HHHHH------TTSS--S?-?GGGHHHHHHHHHHHHHHHHTT--SEEEE?S???SHHHHHHHHHHHHHTT?EEEEEEEE??-----------------HHHHHHHH-----HTTT?S---------------------------------------------------------S?HHHHHHHHHH???TTSS?GGG??SEEEE------TTS???H----------------------HHHHHHH----------------HHHHTS??SSSTT????S???HHHHHHHHHHHHHHHHHHH----HTT??HHH---------------------------------HHHHHHHHHHHHHHHT------T?S???HHHHHHHHHHHHH 4GP7|A PF08435.6_Calici_coat_C_seed 29 251 !Q:2,2|6,6|8,9|20,22|34,34|36,36|39,46|63,63|74,74|76,86|100,107|112,114|117,117|121,123|125,128|130,132|145,146|149,149|152,153|155,157|164,164|175,178|210,211|213,214|220,222|225,225|234,234|237,250 Q:0,1|3,5|7,7|10,19|23,33|35,35|37,38|47,62|64,73|75,75|87,99|108,111|115,116|118,120|124,124|129,129|133,144|147,148|150,151|154,154|158,163|165,174|179,209|212,212|215,219|223,224|226,233|235,236 EE?TTS?B??TTSSSSSSTT???SBSEEEEEEEE-E?ST--------TEEEEEEEEEETTSTT?BGGGTEEEEE?S?-----??-??TTSEEEEEEEEEE????????BTTS???TT?TTS???S????B???STTEEEEEEEEE??EE-EE--E???EEEESS?HHHHHHHHHH????SSSEEEEEEEETTTTEEEEEEEEETTTEEEE--E??SSEEE???TT?EEEEEEEE?TT?????????????? 3R6K|A PF08436.7_DXP_redisom_C_seed 88 90 !Q:3,3|14,15|18,18|22,27|36,38|43,44|51,52|58,65 Q:0,2|4,13|16,17|19,21|28,35|39,42|45,50|53,57|66,89 EEE?SHHHHHHHHH??TT?GGG------EEEEEEEE???TTTT??HHHHTT??HHHHH????????HHHHHHHHHTHHHHHHHHHHHHHH 1ONP|A PF08438.5_MMR_HSR1_C_seed 93 158 !Q:3,3|6,6|8,8|10,12|22,27|34,34|40,40|50,50|54,59|61,105|120,133|148,148|157,157 Q:0,2|4,5|7,7|9,9|13,21|28,33|35,39|41,49|51,53|60,60|106,119|134,147|149,156 EEE?GG-G-S--?HHHHHHHHH------HHHHTT?EEEEE?HHHHHHHHS?SSS????--S????????---?????----------------------???????TTHHHHHHTSSSSS-------------?SHHHHHHHHHHTTS?EEEEEEES? 1WXQ|A PF08439.5_Peptidase_M3_N_seed 182 76 !Q:5,5|15,15|17,17|19,21|34,34|41,43|54,54|73,75 Q:0,4|6,14|16,16|18,18|22,33|35,40|44,53|55,72 HHTTS?HHHHHHHHH-H?G---GGGGGHHHHHHH-HTTGGG???HHHHHHHHHT-HHHHHHHHHHHHHHHHTT??? 3CE2|A PF08441.7_Integrin_alpha2_seed 97 879 !Q:1,2|7,7|18,19|24,30|33,33|35,36|40,40|42,43|45,46|58,58|61,68|83,84|86,86|90,92|97,113|116,116|131,134|136,136|143,144|146,146|149,149|151,152|155,155|165,179|184,185|189,193|196,197|200,203|214,214|216,372|375,382|386,386|390,424|427,433|445,455|458,459|463,463|469,471|480,496|498,498|502,506|508,511|515,516|519,524|530,533|537,537|539,540|542,542|553,555|558,566|568,568|578,580|582,582|584,584|588,591|593,595|604,614|618,618|629,642|645,645|648,651|654,655|661,665|669,669|677,677|681,684|701,711|719,731|736,736|738,738|741,756|760,760|765,798|800,800|802,825|828,861|863,863|868,871 Q:0,0|3,6|8,17|20,23|31,32|34,34|37,39|41,41|44,44|47,57|59,60|69,82|85,85|87,89|93,96|114,115|117,130|135,135|137,142|145,145|147,148|150,150|153,154|156,164|180,183|186,188|194,195|198,199|204,213|215,215|373,374|383,385|387,389|425,426|434,444|456,457|460,462|464,468|472,479|497,497|499,501|507,507|512,514|517,518|525,529|534,536|538,538|541,541|543,552|556,557|567,567|569,577|581,581|583,583|585,587|592,592|596,603|615,617|619,628|643,644|646,647|652,653|656,660|666,668|670,676|678,680|685,700|712,718|732,735|737,737|739,740|757,759|761,764|799,799|801,801|826,827|862,862|864,867|872,878 B??EEEE-EEEEEEESSE--EETT???----SB?T--TSS?B??E--EEEEEEEEEEE?SS------??SEEEEEEEEEESTT--S?TTS???EEET-----------------TT?SSEEEEEEEEEBSS????E-EEEEEE??G-GG?S??SS?EEEEEEEEE--------------?SSTT??SSS??--?EE-?SS--??SEEEEEEEEE?S-----------------------------------------------------------------------------------------------------------------------------------------------------------??SS?--?????EEE-EEE????--?----------------------------EE??-??--EEEEEEEEEEE----------?SS-?BTT?EEEEE?-?SSEEEEEE?---------------?S?SSS???-?E----EEE??TT??----EEEEE?--?SSB?T--T?EEEEEEEEEE???SS---------S?SEEEEEEEE---E?S?SSS?---B???EEEEEEEE????-------EEE-EEEEESSEEE--------------ES?TT????SS??SHHHH??---EEE-EEEEEEE?SSS---?BSEEEEEEEEEEESSS?--------??EEEEEEE-------------EESS?E-EE----------------ESS?SSTT????-----------------------???????S?S????????????????????????EE----------------------------------E?TTTS----EEEEEEE 4G1E|A PF08442.5_ATP-grasp_2_seed 22 212 !Q:1,2|15,19|37,37|40,40|46,47|51,52|56,64|66,66|71,71|89,90|94,94|97,97|100,102|108,110|135,135|139,139|147,147|156,156|162,163|176,177|179,179 Q:0,0|3,14|20,36|38,39|41,45|48,50|53,55|65,65|67,70|72,88|91,93|95,96|98,99|103,107|111,134|136,138|140,146|148,155|157,161|164,175|178,178|180,211 B??HHHHHHHHHHTT?????EEEESSHHHHHHHHHHH?SS?EEEEE??SSS??GGG---------T?EEEE?SHHHHHHHHHHHTTSEE??TTS?TT?EE???EEEEE???EEEEEEEEEEEETTTTEEEEEEES?TTS?HHHHHHH?GGGEEEEE?BTTTB??HHHHHHHHHHTT??T-HHHHHHHHHHHHHHHHHHHTTEEEEEEEEEEE 2YW2|A PF08443.6_RimK_seed 5 209 !Q:2,2|15,27|34,34|36,36|45,49|57,57|62,63|69,69|87,92|98,99|102,102|104,107|126,127|131,134|139,139|144,147|163,163|170,170|187,189|197,199 Q:0,1|3,14|28,33|35,35|37,44|50,56|58,61|64,68|70,86|93,97|100,101|103,103|108,125|128,130|135,138|140,143|148,162|164,169|171,186|190,196|200,208 HH?HHHHHHHHHHTT--------?????EEEESS?S?HHHHHHTT?---?SSEEEEE?TTTT??EEEEE?SHHHHHHHHHHHHTGGG??----EEEEE??SS?S---?EEEEEEETTEEEEEEEEE??SSS????TTTT?EEEE????HHHHHHHHHHHHHTT?SEEEEE-EEEETTEEEEEEEESS???HHHHHHH???HHHHHHHHH 3HO8|A PF08445.5_FR47_seed 9 92 !Q:7,8|11,12|20,20|23,23|32,32|36,36|57,57|59,59|68,68|80,80|84,85 Q:0,6|9,10|13,19|21,22|24,31|33,35|37,56|58,58|60,67|69,79|81,83|86,91 EEEEEET--TT??EEEEEEE?TT-SSEEEEEE?GGG?SSSHHHHHHHHHHHHHHHHS?S?EEEEEETT?HHHHHHHHHHT?EEE--EEEEEE 1S3Z|A PF08446.6_PAS_2_seed 41 161 !Q:3,4|8,9|12,12|21,21|25,28|45,62|67,89|98,98|103,106|109,111|125,125|143,146|149,150|152,152|160,160 Q:0,2|5,7|10,11|13,20|22,24|29,44|63,66|90,97|99,102|107,108|112,124|126,142|147,148|151,151|153,159 HHT??GGG??EE?TTSEEEEE-ETT----TTEEEEEETTHHHHHS??----------------HHHH-----------------------TTSBHHHH?EESS????SS???HHHHHHTSSEEEE-EEETTTEEEEEEEEEEE---?TT--S?EEEEEEE? 3IBR|A PF08447.6_PAS_3_seed 122 108 !Q:0,0|4,4|6,6|9,10|16,17|19,19|23,25|29,34|36,36|51,54|58,63|67,67|73,74|78,78|81,83|94,95|99,99 Q:1,3|5,5|7,8|11,15|18,18|20,22|26,28|35,35|37,50|55,57|64,66|68,72|75,77|79,80|84,93|96,98|100,107 ?EEE?H-HH--HHHTT??G-GGS--?SEE??????B?TTTHHHHHHHHHHH----HHH?-??--EEE-EEEEE?-TTS?EE---EEEEEEEEEE-?TTS?EEEEEEEE 3GDI|A PF08448.5_PAS_4_seed 49 141 !Q:3,3|11,14|18,18|24,24|27,32|36,36|40,41|44,45|48,48|52,53|55,56|58,58|61,69|83,84|94,104|113,114|119,119|123,124|135,140 Q:0,2|4,10|15,17|19,23|25,26|33,35|37,39|42,43|46,47|49,51|54,54|57,57|59,60|70,82|85,93|105,112|115,118|120,122|125,134 HHT?SSEEEEE----ETT?BEEEE?HH------HHH-HTT??SS??TT?BHH--H--H?TT-------??HHHHHHHHHHHTT??EEEEEEEEE?------????EEEEEEEE--EEEE?TTS?-EEEEEEEEEE??---- 1F9I|A PF08450.7_SGL_seed 50 404 !Q:10,20|28,33|53,72|75,75|78,88|95,95|97,99|102,103|115,136|140,141|143,149|153,160|162,165|173,177|179,183|185,186|197,197|201,202|210,211|217,222|224,224|227,227|234,234|237,240|242,247|255,255|265,265|274,278|286,287|307,307|310,311|315,321|323,325|332,332|334,334|337,337|344,348|352,357|369,369|376,376|378,379|381,381|389,389|395,395|403,403 Q:0,9|21,27|34,52|73,74|76,77|89,94|96,96|100,101|104,114|137,139|142,142|150,152|161,161|166,172|178,178|184,184|187,196|198,200|203,209|212,216|223,223|225,226|228,233|235,236|241,241|248,254|256,264|266,273|279,285|288,306|308,309|312,314|322,322|326,331|333,333|335,336|338,343|349,351|358,368|370,375|377,377|380,380|382,388|390,394|396,402 BEEEEEEEGG-----------GTEEEEE------EGGGTEEEEEETTTTEEEE--------------------EE?SS----------?EEEEEE-B---TT--SSEEEEETTEE----------------------EEE--E-------TTT--------T----EEEEEEE?---?T-----T?-SSEEEEEEEE?TTS?-EEEEEEE??SBTTB------S?TT?EEEEEE?TT----S?-----EEEEEEE-ESBEEEEEE?TTSSEEEE-----EEGGGTE--EEEEEEETTTTEEEEEEEE-EE??GGG------?E---EEEEEE?T-TS?EEEEEE-----TTT------EEEEEETTTTE-EEEEEE?S-?S-BEEEEEE-ESGGG?EEEEEEB? 4HHO|A PF08451.6_A_deaminase_N_seed 32 132 !Q:0,53|74,77|90,90|94,95|102,102|106,108|113,113|124,125 Q:54,73|78,89|91,93|96,101|103,105|109,112|114,123|126,131 ----------------------------------------------------??HHHHHHHHHHHHHHHSTTTT????HHHHHHHHHHHH-HHH--HHHHHH-HHH???GGGS?HHHHHHHHTT-?HHHHHH 3LGG|A PF08453.5_Peptidase_M9_N_seed 34 234 !Q:1,2|10,10|21,21|23,23|33,34|43,43|61,62|65,68|88,90|121,121|123,136|152,153|156,158|174,176|188,197|221,221|225,227 Q:0,0|3,9|11,20|22,22|24,32|35,42|44,60|63,64|69,87|91,120|122,122|137,151|154,155|159,173|177,187|198,220|222,224|228,233 B?-HHHHHSS?HHHHHHHHHH-S?GGGBTTSSS??HHHHHHHH?HHHHHHHHHHHHHHHHH??SS?--?TTHHHHHHHHHHHHHHHHH?--GGGHHHHSHHHHGGGHHHHHHHHHSGGGSS?S--------------HHHHHHHHHHHHHHH--HS???HHHHHTTHHHHHHHH---HTHHHHTTSHH----------HHHHHHHHHHHHHHHHHHHTSSS?GGG---STTTTT 2Y6I|A PF08459.6_UvrC_HhH_N_seed 110 243 !Q:7,15|31,31|44,44|48,48|53,74|76,80|82,82|96,97|105,146|154,154|170,179|183,204|209,213|218,221 Q:0,6|16,30|32,43|45,47|49,52|75,75|81,81|83,95|98,104|147,153|155,169|180,182|205,208|214,217|222,242 HHHHHTS?--?----?SEEEEEEEEESSSSS?EEEEEEEETTEE?GGG?EEEE??----?-------------??T-----T?HHHHHHHHHHHHH--HHHHHHT?--------------------------------------???SEEEESS?HHHHHHHHHHHHHTS??--?--??-EEE???????????----------?EETT-----TTEE????TTSHHHHHHHHHHHHHHHHTT 2NRT|A PF08460.5_SH3_5_seed 15 69 !Q:9,10|15,15|24,24|28,28|34,34|37,37|45,45|58,58|61,62 Q:0,8|11,14|16,23|25,27|29,33|35,36|38,44|46,57|59,60|63,68 EEEEEEEEE--EESS?EEEESSSS?TTS?EEEEE?TT?EEEEEEE-EEETTEEEEEEE?TT??EEEEEE 1R77|A PF08462.5_Carmo_coat_C_seed 8 99 !Q:4,4|8,8|10,12|27,27|38,38|45,47|85,85|89,91|98,98 Q:0,3|5,7|9,9|13,26|28,37|39,44|48,84|86,88|92,97 EETT?GGG?S???EEEEEETTEEEEEE?SSEEEEEEEE?SSSSSB???EEESTTEEEEEEEETTTTEEEEEEEESSTTEEEEEEB?TTS???EEEEEE? 1OPO|A PF08468.6_MTS_N_seed 19 162 !Q:13,13|20,22|30,31|41,42|60,62|65,66|73,73|80,81|99,99|102,102|125,125|127,128|132,134|143,143|145,146|148,153|158,158 Q:0,12|14,19|23,29|32,40|43,59|63,64|67,72|74,79|82,98|100,101|103,124|126,126|129,131|135,142|144,144|147,147|154,157|159,161 HHHHHTTHHHHTT?EEEEEE???SSHHHHS??SEEEEEESB--HHHHHHHHHHHGGGEEE?--SS??HHHHTT?SEEEEE??SSHHHHHHHHHHHHTTS?TT?EEEEEEEGGGTGGGHHHHHTTT-S??EEE???TTEEEEEE-E??S???-??GGGG?EEE 2PJD|A PF08470.5_NTNH_C_seed 7 165 !Q:6,6|10,10|12,12|18,18|22,22|34,34|50,51|55,61|66,66|68,68|71,72|74,74|78,78|95,96|106,106|110,112|117,118|121,121|124,124|140,140|143,143|149,149|152,153|155,155|160,160 Q:0,5|7,9|11,11|13,17|19,21|23,33|35,49|52,54|62,65|67,67|69,70|73,73|75,77|79,94|97,105|107,109|113,116|119,120|122,123|125,139|141,142|144,148|150,151|154,154|156,159|161,164 HHHHHH?SSB?B?TTSSB?BTT?EEEEEESSSTT?BEEEEESSSSEEEEE??STT???????EEEE?S?TT??B?BTT?EEEEEEESSSEEEEEE?-TTSBEEEES?GGG???EEEE??TT?TT?BEEEETTEEEEEEEE?SS?EEEEE?SS--S?GGGG?EEEE 3V0A|B PF08477.8_Miro_seed 17 149 !Q:8,8|20,46|49,52|65,65|71,71|77,79|81,87|93,93|97,98|110,110|120,125|137,139|145,146 Q:0,7|9,19|47,48|53,64|66,70|72,76|80,80|88,92|94,96|99,109|111,119|126,136|140,144|147,148 EEEEESSS?SSHHHHHHHHH?????------------??????????EE----EEEGGGSGGGTT?STTTT?EEEEE???S?-----?TTTTT?HHH--HHSSEEEEEEE?GGGGGGHHH------HHHHHHHHSSS-??EEEEE??TT 2ZEJ|A PF08478.5_POTRA_1_seed 92 77 !Q:0,3|10,11|14,15|27,29|35,36|38,38|49,51|63,63|67,67|76,76 Q:4,9|12,13|16,26|30,34|37,37|39,48|52,62|64,66|68,75 ????EEEEES??SS??HHHHHHHHTTS?-?SSTTT--S?HHHHHHHHTS?-?SSEEEEEEEEE-TTT-EEEEEEEE? 2VH1|A PF08479.6_POTRA_2_seed 60 92 !Q:0,4|9,10|13,13|15,15|17,27|29,29|40,42|62,62|65,65|69,70|73,78|82,83|90,91 Q:5,8|11,12|14,14|16,16|28,28|30,39|43,61|63,64|66,68|71,72|79,81|84,89 ?????EEEE??TT?S?S-----------S?SGGGGGGSSS???HHHHHHHHHHHHHHHHHTT?TT?EEE??TT?---?-SSS?-EEEEEE?? 3NJT|A PF08484.6_Methyltransf_14_seed 24 164 !Q:1,1|18,20|22,25|71,72|77,79|91,92|97,98|103,103|111,112|116,117|125,126|129,130|137,137|156,156|161,161 Q:0,0|2,17|21,21|26,70|73,76|80,90|93,96|99,102|104,110|113,115|118,124|127,128|131,136|138,155|157,160|162,163 E?GGGSEEEEEEEETTSS???H----HHHHHHHHHHHTTTTSHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??EEEE???STHHHHHHHHT??TTTS??EEES?GGGTTEE?-TTT??EEEEGGG??SS??SEEEES?GGGHHHHHHHTHHHHHTT?EEEE?SS 4E2Z|A PF08485.5_Polysacc_syn_2C_seed 50 51 !Q:0,25|32,32|34,35|46,46 Q:26,31|33,33|36,45|47,50 ?????????????????????---??EETTTS?B??HHHHHHHHTT?HHHH 3VVB|A PF08489.6_DUF1743_seed 59 139 !Q:0,0|12,24|26,29|31,31|39,40|47,50|52,52|59,59|69,69|72,72|79,79|83,84|94,96|100,100|111,113|115,115|117,125|132,132|136,136 Q:1,11|25,25|30,30|32,38|41,46|51,51|53,58|60,68|70,71|73,78|80,82|85,93|97,99|101,110|114,114|116,116|126,131|133,135|137,138 ?THHHHHHHHHH?---?-------?S----S?EEEEEEE??GGGTTS-???B?HHHHHH-HHHHHTTSB?SS?BTTTTB?TTS??SSSSEEEEE---EES?HHHHHHHHHH?-?B-S-----????EEEEEE?TTS?TT 3AU7|A PF08491.5_SE_seed 13 287 !Q:0,4|7,9|12,12|20,29|36,37|43,43|49,49|53,58|73,74|98,99|109,111|114,114|116,116|119,123|126,126|128,128|132,134|140,140|147,148|152,153|170,170|173,175|182,182|190,190|201,206|221,221|223,223|232,286 Q:5,6|10,11|13,19|30,35|38,42|44,48|50,52|59,72|75,97|100,108|112,113|115,115|117,118|124,125|127,127|129,131|135,139|141,146|149,151|154,169|171,172|176,181|183,189|191,200|207,220|222,222|224,231 -----EE???TT?HHHHHTS-?????????EEEEEE??HHHHH?EEEEE?EEE------EEEETTTEEEEEEE??HHHHHHHHHSTTSHHHHHHHHTT??GGGHHHHHT???ST-T?EE?????EE?S?SEE---TTEEE?GGGTEE??GGG??HHHHHHHHHHHHHHHH-HH---HHTTSS?HHHHHHH-HHHHHHHHHH------HHHHHHHHHHHHTT?H-HHHHHHHH??????????????----------------------------????--------? 4HB9|A PF08501.6_Shikimate_dh_N_seed 40 100 !Q:5,5|7,7|9,9|20,23|28,30|38,46|54,54|61,63|66,67|72,72|83,83|87,87|95,97 Q:0,4|6,6|8,8|10,19|24,27|31,37|47,53|55,60|64,65|68,71|73,82|84,86|88,94|98,99 EEESS?T-T?SHHHHHHHHH----HHTT?-?EEEEEEE??-------GGGGGGH-HHHHHH---HT??EEEE?TTSTTGGGGG?SEE?HHHHHHT???EE 4FQ8|A PF08502.5_LeuA_dimer_seed 57 199 !Q:0,2|17,41|53,54|57,64|67,68|78,79|84,89|110,110|113,116|119,121|135,135|138,139|150,170|198,198 Q:3,16|42,52|55,56|65,66|69,77|80,83|90,109|111,112|117,118|122,134|136,137|140,149|171,197 ???HHHHHHHHHHHHTS----------------------??-SSEEEEEEEEE??SS--------TT??EEEEEEEEE--TTEE------EEEEEEESSHHHHHHHHHHT-TT?---EE---EEEEEEEEESSSS-TT??EEEEEEEEEE?????-???????????????EEEEEEEEESSHHHHHHHHHHHHHHHH? 3HQ1|A PF08503.5_DapH_N_seed 38 86 !Q:0,0|12,14|16,16|25,26|30,34|42,42|74,75|79,79|81,81|83,85 Q:1,11|15,15|17,24|27,29|35,41|43,73|76,78|80,80|82,82 ?HHHHHHHHHHH???B?EEEEEEEE?-TTS???-?TTSEEEE?SSEEEEEEEHHHHHHHHHHTTTTEEEEEEEE??BSB?S?B??? 3BV8|A PF08506.5_Cse1_seed 15 379 !Q:7,10|42,44|46,46|48,48|73,75|95,98|102,103|106,106|110,111|131,131|153,155|157,157|185,185|204,205|225,225|228,230|269,269|273,274|290,290|292,294|297,299|301,301|303,304|308,308|323,324|327,327|329,329|348,348|367,367 Q:0,6|11,41|45,45|47,47|49,72|76,94|99,101|104,105|107,109|112,130|132,152|156,156|158,184|186,203|206,224|226,227|231,268|270,272|275,289|291,291|295,296|300,300|302,302|305,307|309,322|325,326|328,328|330,347|349,366|368,378 HHTTTTT????TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--?T-T?HHHHHHHHHHHHHHHHHHHHHHSS???HHHHHTHHHHHHHHHHHHH???-GGG??TT?SSS??HHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHHHTT-??S?GGGHHHHHHHHHHHHHHHTSHHHHTTT?SHHHHHHHHHHTHHHHHS??HHHHHHHHHSHHHHHHHHS?SS???SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?TTT??HHHHHHHHHHHHHHB?S???TT-??S?B-?TTS?HHHHHHHHTSHHHH-?SS?S?HHHHHHHHHHHHHHGGGS?HHHHHTTHHHHHHHTTSS?HHHHHHHHHHH 1Z3H|A PF08511.6_COQ9_seed 70 88 !Q:0,0|8,23|27,37|50,57|60,61|82,87 Q:1,7|24,26|38,49|58,59|62,81 -HHHHHHT????----????????HHH-----------HHHHHHHHHHHH--------HT??SGGGHHHHHHHHHHHHHHHH?????? 3NI7|A PF08512.7_Rtt106_seed 156 137 !Q:0,0|2,2|13,15|17,19|26,31|36,36|41,41|49,49|57,71|80,80|82,93|95,102|104,105|116,116|124,124|131,132|135,136 Q:1,1|3,12|16,16|20,25|32,35|37,40|42,48|50,56|72,79|81,81|94,94|103,103|106,115|117,123|125,130|133,134 ?S?EEEEETTEEE---E---EEEETT------EEEE-ESSS?EEEEGGG-EEEEEEE???-----???????EEEEEEEE-S------------T--------T??EEEEEEEEGG-GHHHHHH-HHHHTT??EE?? 3GYP|A PF08513.6_LisH_seed 58 27 !Q:15,15 Q:0,14|16,26 HHHHHHHHHHHHHTT?HHHHHHHHHHT 2XTD|A PF08515.7_TGF_beta_GS_seed 28 34 !Q:0,1|8,9|16,17|19,19|21,24 Q:2,7|10,15|18,18|20,20|25,33 ??HHHHHH--HHHSSS--S?S-???HHHHHHHHT 2X7O|A PF08516.7_ADAM_CR_seed 68 142 !Q:2,2|7,7|19,19|29,29|32,33|35,36|51,51|53,53|55,55|58,60|63,65|68,71|80,81|85,86|89,89|95,98|100,101|112,112|119,120|123,123|126,133|136,136|141,141 Q:0,1|3,6|8,18|20,28|30,31|34,34|37,50|52,52|54,54|56,57|61,62|66,67|72,79|82,84|87,88|90,94|99,99|102,111|113,118|121,122|124,125|134,135|137,140 TT?EETT-TTEEEETTEEE?HHHHHHHHH?TT??B??HHHHHHHTTTTBTT-B?S?BS---SS---SB????GGGTTSSB??BSS??SS?SSSEE---?S??EEEEEEETTE-EEEEEE??EE-SS--------SS?EETB? 3DSL|A PF08517.7_AXH_seed 10 129 !Q:1,1|4,4|13,14|16,16|20,21|28,28|33,34|38,38|41,41|49,49|72,72|78,79|85,85|88,89|111,113|116,117|120,120|123,124|127,127 Q:0,0|2,3|5,12|15,15|17,19|22,27|29,32|35,37|39,40|42,48|50,71|73,77|80,84|86,87|90,110|114,115|118,119|121,122|125,126|128,128 B?TT?EEEETTSS??S?EEH--HHHHHH-TTSS??TTT?TT?STTTTSS?EEEEEEEEEEETTEEEEEEEEE?SSGGG??EEEEE?TT??EEETTTEEEESSHHHHHHHHS???EE??TT?EE??TT?T 1OA8|A PF08519.7_RFC1_seed 48 186 !Q:13,13|16,17|37,37|40,44|47,60|86,95|104,104|111,111|115,128|138,139|147,147|152,185 Q:0,12|14,15|18,36|38,39|45,46|61,85|96,103|105,110|112,114|129,137|140,146|148,151 HHHHHHHHHHHTT?SS-?GGGHHHHHHHHTHHHHHTT?EE----?SS-???--------??SHHHHHHHHHHHHHHHHHHHTTTTT??----????HHHHHTTT-HHHHHH-HHS????????-----?HHHHHHTTT??SHHHHHH-HHHH???----??????????????????????????? 1SXJ|A PF08522.5_DUF1735_seed 101 124 !Q:0,1|3,3|6,6|10,10|13,13|22,25|30,30|33,33|37,39|42,43|46,48|52,53|55,56|61,61|64,68|72,72|79,79|81,89|91,93|97,97|106,106|108,108|110,116|118,123 Q:2,2|4,5|7,9|11,12|14,21|26,29|31,32|34,36|40,41|44,45|49,51|54,54|57,60|62,63|69,71|73,78|80,80|90,90|94,96|98,105|107,107|109,109|117,117 ??S?EE-EEE-EE?HHHHHHHH----HHHH?TT?GGG??-EE??GG---GEE??S--EEEE?TT--??-EEE-EEEEEE?T---------T?-?TTS?EEEEEEEE-E?S?------S?????? 3P02|A PF08526.5_PAD_N_seed 15 114 !Q:0,4|8,9|13,13|23,23|28,28|30,38|44,44|52,71|74,75|83,84|89,89|97,97|102,106 Q:5,7|10,12|14,22|24,27|29,29|39,43|45,51|72,73|76,82|85,88|90,96|98,101|107,113 ?????EEE??SSS?EEEEEETTS?EEEE?S?????????EEEEE?TTEEEEE?????-??????????????TT??EEEEESS??SSSS?EEEEEEE?BTTB--???EEEEEEE 1WD8|A PF08527.5_PAD_M_seed 15 185 !Q:6,7|13,24|26,28|32,34|38,38|40,71|88,88|102,102|115,135|144,144|149,152|165,168|173,173 Q:0,5|8,12|25,25|29,31|35,37|39,39|72,87|89,101|103,114|136,143|145,148|153,164|169,172|174,184 EEEEEE??TTSSS????????????S???STT???EEE?B????????????-----------?????????GGGTSSSEEEEEEEEE?TTGGGTEEEEEEE?TTTGGGEEEEEE????-------------????EEEEESSS?SEEE????SEEEEEEEEEEE????BTTB?SEEEEEEEEEE 1WD8|A PF08529.6_NusA_N_seed 161 177 !Q:0,0|2,2|14,16|33,38|42,42|44,54|57,57|59,59|65,65|69,70|77,77|80,82|84,98|100,104|106,107|112,112|117,119|121,121|127,131|133,134|137,139|143,148|150,152|169,169 Q:1,1|3,13|17,32|39,41|43,43|55,56|58,58|60,64|66,68|71,76|78,79|83,83|99,99|105,105|108,111|113,116|120,120|122,126|132,132|135,136|140,142|149,149|153,168|170,176 ?H-HHHHHHHHHHT???HHHHHHHHHHHHHHHH------HHH-S----?------SS-S?EEEEE?TTT??EEEEEE?EE?--S?-----------?--S----?T--TTEE?HHHH---H-TTSSS?---?S--SB??-EEE?--???S--?HHHHHHHHHHHHHHHH-HHHHHHH 1K0R|A PF08530.5_PepX_C_seed 53 440 !Q:6,7|15,15|20,54|60,60|63,63|66,66|70,74|80,85|88,89|95,96|102,103|106,106|110,112|117,117|119,127|130,131|133,134|138,138|143,147|149,149|152,152|154,154|157,169|173,173|176,176|181,184|187,187|206,212|214,215|225,231|234,254|256,256|258,277|283,286|296,296|300,343|346,347|362,362|365,365|374,375|380,383|388,390|394,395|397,418|421,423|435,436 Q:0,5|8,14|16,19|55,59|61,62|64,65|67,69|75,79|86,87|90,94|97,101|104,105|107,109|113,116|118,118|128,129|132,132|135,137|139,142|148,148|150,151|153,153|155,156|170,172|174,175|177,180|185,186|188,205|213,213|216,224|232,233|255,255|257,257|278,282|287,295|297,299|344,345|348,361|363,364|366,373|376,379|384,387|391,393|396,396|419,420|424,434|437,439 TTTTTT??SEEEEEB-TTTE-----------------------------------EEEES?SS?TT?EEE-----EEEEE-----?SS??BSTTS??EEESS??SS?EEE---EEEE?T---------TS??B??STT?SSSS?----S?SS?B?GG-------------GTT?TT?EEEE????SS?EEEEEEEEEEEEEEESSS-------S?-EEEEEEEEE------?TT---------------------S?E--------------------EEEEE----EEEEGGGSS?SSS?---------------------------------------????TT??EEEEEEEEEEEEEE?TT?EEEEEEES??BTTS????SSSS--?GGG??G----------------------GG???EEEEEEESSSS??EEE 1JU4|A PF08531.5_Bac_rhamnosid_N_seed 25 238 !Q:1,1|24,24|27,27|29,37|41,44|56,56|60,61|63,63|65,65|75,75|81,82|86,96|98,98|101,102|105,105|117,117|120,120|125,125|127,127|131,131|135,137|145,148|152,153|161,162|170,174|178,197|200,200|203,218|220,222|228,229|231,232 Q:0,0|2,23|25,26|28,28|38,40|45,55|57,59|62,62|64,64|66,74|76,80|83,85|97,97|99,100|103,104|106,116|118,119|121,124|126,126|128,130|132,134|138,144|149,151|154,160|163,169|175,177|198,199|201,202|219,219|223,227|230,230|233,237 S?EEEEEEEEEEESEEEEEETTEE?SS?S---------SBT????TTTEEEEEEEE?TTT??S-E-EEEEEEEEE?HHHHS??TTS?----------S?SS?-SS?EEEEEEEEEET-TS?EEEE-E?STT?EEE-??SEEEEET----TTE--EEEEGGG??TTTTSTT??--?TTS--------------------EE?EE--------------??S???SEEEE??S??EEEEE 3W5M|A PF08532.5_Glyco_hydro_42M_seed 27 265 !Q:0,0|5,8|10,11|21,23|26,26|29,40|57,58|63,63|67,68|72,75|83,84|86,87|102,102|110,110|112,112|114,114|118,118|120,121|128,131|141,141|147,148|151,156|162,162|166,166|171,171|184,186|194,195|200,200|202,203|208,210|213,213|216,219|228,229|236,236|238,242|245,245|260,260|263,264 Q:1,4|9,9|12,20|24,25|27,28|41,56|59,62|64,66|69,71|76,82|85,85|88,101|103,109|111,111|113,113|115,117|119,119|122,127|132,140|142,146|149,150|157,161|163,165|167,170|172,183|187,193|196,199|201,201|204,207|211,212|214,215|220,227|230,235|237,237|243,244|246,259|261,262 ?SEEE----E??HHHHHHHHH???SB-TT??----------HHHHHHHHHHHHHHTT??EEEE?TTS-?GGG---?SEEEETT??B??TTHHHHHHHHHHTT?EEEEETT?S?B?TTS?B??SSBTGG----GHHHHTEEE-EEEEE??TT-----?EEEEE-ESS?BTTB?SEEEEEEEEEEE---EESSSEE--EEEE?S--STTT---TS-EE----EEEEEETT--EEEEEE?E-----EE?HHHHHHHHHHHHHH-TT?? 3TTS|A PF08533.5_Glyco_hydro_42C_seed 26 68 !Q:6,12|22,22|26,26|29,36|39,39|45,54|58,58|67,67 Q:0,5|13,21|23,25|27,28|37,38|40,44|55,57|59,66 TEEEEE-------ETTEEEEEE?SSS?EE???----?TT?EEEES?---------SEE?TTEEEEEE? 3TTS|A PF08534.5_Redoxin_seed 68 251 !Q:0,6|9,9|11,19|26,30|32,33|36,40|51,56|61,61|63,63|67,70|75,75|78,78|81,96|110,110|114,114|119,120|125,134|139,139|142,149|159,165|167,167|170,170|175,175|178,180|182,182|184,184|192,194|198,198|203,206|210,211|220,221|229,231|233,233|235,241 Q:7,8|10,10|20,25|31,31|34,35|41,50|57,60|62,62|64,66|71,74|76,77|79,80|97,109|111,113|115,118|121,124|135,138|140,141|150,158|166,166|168,169|171,174|176,177|181,181|183,183|185,191|195,197|199,202|207,209|212,219|222,228|232,232|234,234|242,250 ?------TT?B--?-?--??EEEEEE----?S??TT---??SEEEEEEHHH------HHTT?E-EEE----EEES?TT?HH----------------HHHTHHHHHHHHH-HHH-HHTT??EEEE----------EESS?HH--------HHHHHHHHT-------T?TT-TSEE-EE?--T-T?HHHHHHT--?EEE?GGGT?--?EEE??EEEEEETT--EEEEEEE??-T-T?-----?SSSSHHHHH 1URM|A PF08535.5_KorB_seed 17 97 !Q:3,4|14,15|28,29|41,43|57,57|66,70|72,72|75,77|91,97 Q:0,2|5,13|16,27|30,40|44,56|58,65|71,71|73,74|78,90 HTT??HHHHHHHHT??HHHHHHHHGGGS??HHHHHHHHTTS???HHHHHHHHHHHHH?HHHHHHHH-----H?TT???SHHHHHHHHHHHH??????- 1R71|A PF08536.6_Whirly_seed 4 143 !Q:3,3|14,15|30,31|47,47|51,51|57,57|67,69|72,73|79,90|100,100|105,105|125,125 Q:0,2|4,13|16,29|32,46|48,50|52,56|58,66|70,71|74,78|91,99|101,104|106,124|126,142 EEE?SSEEEEEEEE??EEEEEGGGTEEEEE??EEEEEEEEEEETTEE?GGG?EEEEE?HHHHHHHHT-??TT??EEEEE???-????????EEEEEEEEE?TTSS-EEEEEEEEEETTTTEEEEE-EEEEEHHHHHHHHHHHH 3N1H|A PF08538.5_DUF1749_seed 8 395 !Q:0,10|23,28|38,38|41,42|47,50|55,56|59,60|63,63|75,82|86,86|92,93|101,101|103,104|124,136|156,156|159,179|192,194|201,210|229,233|235,235|238,242|250,253|256,258|262,264|268,268|270,287|303,304|306,314|321,322|325,328|331,332|347,348|354,356|358,365|367,367|371,375|379,381 Q:11,22|29,37|39,40|43,46|51,54|57,58|61,62|64,74|83,85|87,91|94,100|102,102|105,123|137,155|157,158|180,191|195,200|211,228|234,234|236,237|243,249|254,255|259,261|265,267|269,269|288,302|305,305|315,320|323,324|329,330|333,346|349,353|357,357|366,366|368,370|376,378|382,394 ??????---??EEEEEEEEEEET------TEEEEEEEE?TT--SSSE----EEEE??TT??TT?STTHHHHHHHH--------TTT?EEEEE??GGGBTTS?S??HHHHHHHHHHHHHHHHHHS---------????EEEEEEGGGHHHHHHHHHH?TT---------------------GGGEEEEEEEEE???TTSTTT----------SHHHHHHHHHHHHHHHHH-----T?TT?----GGGGTTT?---SS???HHH---HHT?S----------?-------SSHHHHTTHHHTGGG??S--------?EEEEEE??TT????HH--HHHHHHHHHHSSSS-?EEEEE???E--------E?TTS----?EEE??-HHHHHHHHHHHHH 2Q0X|A PF08540.5_HMG_CoA_synt_C_seed 10 295 !Q:3,3|6,7|12,15|19,23|26,26|28,29|32,32|55,56|66,72|76,76|82,83|104,104|106,106|114,114|121,122|125,126|133,133|163,165|182,182|189,190|211,211|213,214|235,235|242,242|259,260|263,265|267,269|274,274|277,277|284,284|288,288|294,295 Q:0,2|4,5|8,11|16,18|24,25|27,27|30,31|33,54|57,65|73,75|77,81|84,103|105,105|107,113|115,120|123,124|127,132|134,162|166,181|183,188|191,210|212,212|215,234|236,241|243,258|261,262|266,266|270,273|275,276|278,283|285,287|289,293 EEE?TT??EEEE????SEE??--?TT?S??EE?HHHHHHHHHHHHHHHHHHHHHH--HHHHHHHTT?-?????GGG?SEEEE??SSHHHHHHHHHHHHHHHHHH-S?HHHHHHH?GGGGGG--TT??GGGGGT?HHHHHHHHHHHHHHHHHHTGGGGHHHHHH???GGGHHHHHHHHHHHHS?HHHHTT-?EEEEEEEETTTEEEEEEEEE?S??STTSHHHHHHHTTTTHHHHH-HTSEEE?HHHHHHHHHHHHHHTT??SB???S?--GGGS?TT?EEEEEE?TTS?EEEEE?- 2HDB|A PF08541.5_ACP_syn_III_C_seed 187 99 !Q:4,4|6,7|11,11|17,18|20,20|27,27|34,36|39,40|43,45|47,47|51,51|53,53|70,71|74,74|77,77|84,84|98,98 Q:0,3|5,5|8,10|12,16|19,19|21,26|28,33|37,38|41,42|46,46|48,50|52,52|54,69|72,73|75,76|78,83|85,97 HHHH-T??GGG?SEEEE??S?HHHHHH-HHHTTT??-GG--GB???H-HHH?B?GGGHHHHHHHHHHHHT--SS?TT?EEEEEE-EETTTEEEEEEEE? 3OIT|A PF08542.6_Rep_fac_C_seed 117 123 !Q:1,3|9,9|18,18|20,25|29,46|53,53|59,60|62,64|80,84|86,87|109,110 Q:0,0|4,8|10,17|19,19|26,28|47,52|54,58|61,61|65,79|85,85|88,108|111,122 T???HHHHH-HHHHHHHH-T-----?HHH------------------HHHHHH-HHHHH--S???HHHHHHHHHHHHHTS----?S?-TTHHHHHHHHHHHHHHHHHTT??HHHHHHHHHHHH 2CHQ|A PF08543.7_Phos_pyr_kin_seed 132 305 !Q:19,19|33,34|44,45|48,48|62,63|69,72|81,82|87,87|90,90|93,94|99,112|116,116|124,125|128,128|131,131|135,136|143,147|151,155|157,162|166,167|179,179|181,183|185,185|187,187|191,192|196,196|198,216|219,220|225,228|234,234|240,244|246,247|266,267|285,288|290,293|295,296|299,299|301,304 Q:0,18|20,32|35,43|46,47|49,61|64,68|73,80|83,86|88,89|91,92|95,98|113,115|117,123|126,127|129,130|132,134|137,142|148,150|156,156|163,165|168,178|180,180|184,184|186,186|188,190|193,195|197,197|217,218|221,224|229,233|235,239|245,245|248,265|268,284|289,289|294,294|297,298|300,300 ETTSSSHHHHHHHHHHHTT?EEEEEEEEEEEEE--TTEEEEEEE??HH-HHHHHHHHHHHHS??SEEEE????SHHHHHHH--HHHH-HH-TT??SEEE??????????????HHH-HHHHHHH--TG-GG?SEE??BHHHHH-----HHH?----S???---SHH--HHHHHHHHHHT-T---S?S?EEE--EEE-E-?-??------------??EE--EEEE----ETTEE-EEEEE?????S??TTHHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHH----T????S--SS-S???? 1JXH|A PF08544.8_GHMP_kinases_C_seed 121 131 !Q:5,9|12,24|26,26|40,47|52,53|56,59|70,70|75,80|86,86|89,89|99,111 Q:0,4|10,11|25,25|27,39|48,51|54,55|60,69|71,74|81,85|87,88|90,98|112,130 HHHHH-----HT-------------T?HHHHHHHHHHHHH--------HHHH--TT????HHHHHHHHHH-HHTT-----?SEEEE?SS?SEEEEEEEE-------------EGGGHHHHHHHHHHHHHHH 2DEJ|A PF08545.5_ACP_syn_III_seed 170 118 !Q:4,5|7,9|28,28|30,30|44,44|46,47|49,51|53,58|64,67|70,70|72,73|84,89|92,99|101,102|106,108|114,116 Q:0,3|6,6|10,27|29,29|31,43|45,45|48,48|52,52|59,63|68,69|71,71|74,83|90,91|100,100|103,105|109,113|117,117 EEEE?-G---GGHHHHHHHHHHHHHHTT-S?SEEEEEEEEEGGG-G??T---T---?--TTTTT----TB?E--EEEEEEEEEE------SS?-------S--EEE---EEEEE--?G 3OIT|A PF08546.6_ApbA_C_seed 112 230 !Q:14,18|29,33|35,35|40,43|45,45|47,49|64,72|77,108|111,112|114,134|146,155|159,168|174,174|179,182|188,188|195,195|197,201|207,212|221,221|224,224|227,227 Q:0,13|19,28|34,34|36,39|44,44|46,46|50,63|73,76|109,110|113,113|135,145|156,158|169,173|175,178|183,187|189,194|196,196|202,206|213,220|222,223|225,226|228,229 THHHHHHHHHHHHH-----HHHHHHHHHT---??G-GGGG----G?H---HHHHHHHHHHHHHH---------HHTT---------------------------??-??HH--H---------------------HHHHHHHHHHH----------TTT-----?--??HHHHH-HHTT?-??SGGGT-HHHHHH-H-----HHHTT??---?HHHHHHHH-HH-HH-HH 3GHY|A PF08548.6_Peptidase_M10_C_seed 15 226 !Q:1,1|6,6|8,9|15,16|18,19|24,24|30,32|36,38|41,42|46,46|49,50|52,53|57,57|61,61|65,65|68,68|71,71|75,75|78,81|85,86|89,90|94,95|98,99|103,104|107,108|112,113|116,117|121,122|125,126|130,132|141,141|147,148|156,156|165,165|172,173|176,177|179,179|199,199|202,203|206,207|216,218|225,225 Q:0,0|2,5|7,7|10,14|17,17|20,23|25,29|33,35|39,40|43,45|47,48|51,51|54,56|58,60|62,64|66,67|69,70|72,74|76,77|82,84|87,88|91,93|96,97|100,102|105,106|109,111|114,115|118,120|123,124|127,129|133,140|142,146|149,155|157,164|166,171|174,175|178,178|180,198|200,201|204,205|208,215|219,224 B?TTTT?S??EEETT??S??GGGB?SSTTS???EEE???SS??EEE?TT??S??EEE?STT?EEB?TT?BS?EEE?TT????EEE??SS??EEE??SS??EEE??SS??EEE??SS??EEE??SS??EEE???GGGGBTTB?EEESS??TTTSEEE?HHHHHHHT?TTSSEE?-SS??S?TTEEEEEEETTTTEEEEEE?SS??SS-?SEEEEEES???TTTSEE? 3HB2|P PF08558.5_TRF_seed 27 354 !Q:3,7|14,35|46,67|69,69|87,87|89,91|93,113|133,133|138,138|144,145|147,149|161,161|163,206|227,239|242,242|254,290|304,304|307,307|314,314|350,353 Q:0,2|8,13|36,45|68,68|70,86|88,88|92,92|114,132|134,137|139,143|146,146|150,160|162,162|207,226|240,241|243,253|291,303|305,306|308,313|315,349 HHH-----HHHHHH----------------------HHHHHHHHHH----------------------T?HHHHHHHHHHHHHHHHT?S???H---------------------HHHHHHHHHHHHHHHHTTT?TTEE?SSSTT??H---HHHHHHHHTTS?S???-----------------------------------------HHHHHHHHHHHHHHHHHHHH-------------TT?HHHHHHHHHHH???????-----------------------------?TTHHHHHHHHHTT?TT?HHHHHS?HHHHHHHHHHHHHHHHHHHTTSHHHHHHHHHHHTT?--- 3BQO|A PF08559.5_Cut8_C_seed 19 174 !Q:0,1|21,23|27,27|31,36|65,69|71,73|92,94|127,153|168,168 Q:2,20|24,26|28,30|37,64|70,70|74,91|95,126|154,167|169,173 ??HHHHHHHHHHHHHHHHHTS?--SSS?TTS------HHHHHHHHHHHHHHHHHHHHHGGGGSTB-----T???HHHHHHHHHHHHHHHHTS???SSSGGGHHHHHHHHHHHHHHHHHHHTTSSSSS?????----------------------HHHHHHHHHHTTTT-THHHH 3Q5W|A PF08562.5_Crisp_seed 26 56 !Q:3,3|13,14|16,16|18,20|22,22|33,33|37,37|44,44|50,51|55,55 Q:0,2|4,12|15,15|17,17|21,21|23,32|34,36|38,43|45,49|52,54 TTT?TTSEETTEE??B?S???S?TTHHHHHHHS?TTS-HHHHHH?HHHHH??SSB? 1WVR|A PF08563.6_P53_TAD_seed 12 25 !Q:0,11|23,23 Q:12,22|24,24 ????????????SSTTTTTTTSS?S 2LY4|B PF08564.5_CDC37_C_seed 31 128 !Q:1,4|7,21|23,24|27,36|41,41|44,44|47,58|65,66|85,86|89,127 Q:0,0|5,6|22,22|25,26|37,40|42,43|45,46|59,64|67,84|87,88 T??--TT---------------S??HH----------HHHH-HS?TT????????????HHHHHT??SSSHHHHHHHHHHHHTSS??TT??-------?????????????????????????????? 1US7|B PF08565.6_CDC37_M_seed 19 203 !Q:0,24|36,69|75,78|94,94|114,114|134,136|144,144|146,148|162,165 Q:25,35|70,74|79,93|95,113|115,133|137,143|145,145|149,161|166,202 ??????------?????????????HHHHHHHHHHH----------------------------------HHHHH??--SHHHHHHHHHTTGGG?SHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHH---HHHHHSS?G---GGTHHHHHHHHHT--??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 2W0G|A PF08567.6_TFIIH_BTF_p62_N_seed 19 95 !Q:0,1|10,14|16,16|18,23|30,30|35,35|46,47|56,56|62,63|66,66|76,76|78,86|90,93|95,95 Q:2,9|15,15|17,17|24,29|31,34|36,45|48,55|57,61|64,65|67,75|77,77|87,89|94,94 ??SEEEEESS-----S?E------EEEEEE?SSSS?EEEEEESSSS?-EEEEESTT?SEEEE??TT?SSEEEEEEE?S?-------?SSS????S- 1Y5O|A PF08568.5_Kinetochor_Ybp2_seed 29 986 !Q:0,60|75,86|98,116|119,119|128,128|131,131|156,165|184,184|199,200|202,281|291,298|311,311|313,313|317,318|334,337|339,346|349,349|365,389|396,396|398,400|406,407|426,454|456,468|487,490|494,547|562,562|569,573|584,613|621,631|650,650|653,653|655,665|670,673|692,692|694,695|714,714|718,718|731,732|734,737|755,818|834,835|839,854|857,858|879,887|890,890|894,896|937,951|955,973|980,980 Q:61,74|87,97|117,118|120,127|129,130|132,155|166,183|185,198|201,201|282,290|299,310|312,312|314,316|319,333|338,338|347,348|350,364|390,395|397,397|401,405|408,425|455,455|469,486|491,493|548,561|563,568|574,583|614,620|632,649|651,652|654,654|666,669|674,691|693,693|696,713|715,717|719,730|733,733|738,754|819,833|836,838|855,856|859,878|888,889|891,893|897,936|952,954|974,979|981,985 ?------------------------------------------------------------HHHHHHHHHHHHSS????????????HHHHHHHHHHS-------------------SS?SHHHHHHH-TT?TTHHHHHHTGGGGHHHHHHHHHTS?-------??SSSTHHHHHHHHHHHHHS?GGGHHHHHGGGGTS??G--------------------------------------------------------------------------------GGHHHHHHH--------HHHHHHHHHHHS?S?HHH--HHHHHHHHHHHHHHS???-S????????SS?HHHHHHHHHHHHHHH-------------------------HHHHHS?S???HHHHH--HHHHHHHHHHHHHHHHHH-----------------------------H?????????????HHHHHHHHHHHHHHHSSS?---GGG??????????????????-----------------------------???????HHHHHHHHHHHHTT?TTTTTS?????HHHHHHHHHH------------------------------HHHHHHT??--------?HHHHHHHHHHHHHHHHSS?TT?B?----------GGGG----GSHHHHHHHHHHHHHHHH?S-?HHHHHHHHHHHHHHHHHB?HHH-HHHHHHHHHHHH??H----HHHHHHHHHHHHHHHHT????--------------------------------------------------------????TTTSHHHHHHHHHHS??TTT----------------TT??TTTSHHHHHHHHHHHHHHHH---------HS?TTT?-?SSGGGTHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHH---------------HHT???????---?????????TTGGGH-HHHHH 4F52|E PF08569.6_Mo25_seed 23 445 !Q:0,15|32,46|69,77|81,83|95,96|109,109|112,112|127,128|132,142|144,145|148,153|160,161|174,181|197,224|236,238|241,263|268,272|279,279|308,310|320,320|328,328|360,360|373,373|375,375|392,392|395,396|419,427|442,445 Q:16,31|47,68|78,80|84,94|97,108|110,111|113,126|129,131|143,143|146,147|154,159|162,173|182,196|225,235|239,240|264,267|273,278|280,307|311,319|321,327|329,359|361,372|374,374|376,391|393,394|397,418|428,441 ?????---??-??-??HHHHHHHHHHHHHHHS----------?????SHHHHHHHHHHHHHHHHHHHHH?????????HHH---HHHHHHHHHHH-?HHHHHHHTGGGS?HH-HHHHHHHHHHHHHH??BTT-----------B?-HH------HHHHHT?-THHHHHHHHGGG-------?TTTHHHHHHHHHHHT----------------------------TSHHHHHHHHT---SG-----------------------GGGG-----HHHHTT?SSHHHHHHHHHHHHHHHHSSHHHHHHHH---HHHHHHHHH-HHHHHHT?SSHHHHHHHHHHHHHHHHSGGGHHHHHHHTT?HHHHHHHHHHTT?S?HHHHHHHHHHHHHHHH?SS??HHHHHHHHHTHHHHHHHHTTTT????-????HHHHHHHHHHHHHT???- 4FZA|A PF08581.5_Tup_N_seed 20 82 !Q:34,35|68,81 Q:0,33|36,67 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?????????????? 3VP8|A PF08585.7_DUF1767_seed 34 118 !Q:7,13|30,30|32,36|52,52|57,65|67,67|69,70|75,77|84,94|113,113 Q:0,6|14,29|31,31|37,51|53,56|66,66|68,68|71,74|78,83|95,112|114,117 HHHHHHH?--????HHHHHHHHHHHHHHHT?S--???HHHHHHHHHHHHHTS?HHHH--?---???S?T--TTTT--?SEEEEE-----------EEEEEEEEEEEESHHHHH-HHHH 3NBI|A PF08587.6_UBA_2_seed 7 59 !Q:1,2|13,15|18,18|27,39|41,46 Q:0,0|3,12|16,17|19,26|40,40|47,58 T??TTHHHHHTTT???HH-HHHHHHHS------------?S?----?SSHHHHHHHHHH 3H4J|A PF08596.5_Lgl_C_seed 13 494 !Q:1,2|23,23|32,65|67,68|73,73|75,75|80,80|84,85|88,88|92,93|101,104|106,106|114,114|134,134|143,143|149,158|160,160|163,166|170,175|183,183|200,200|211,211|215,215|225,234|236,237|240,243|249,254|259,260|262,262|264,264|271,275|281,284|291,291|299,299|302,304|310,311|314,314|327,327|331,331|355,356|363,363|365,372|374,376|383,383|386,387|391,392|397,397|410,443|445,447|450,462|467,467|470,475|485,485|488,492 Q:0,0|3,22|24,31|66,66|69,72|74,74|76,79|81,83|86,87|89,91|94,100|105,105|107,113|115,133|135,142|144,148|159,159|161,162|167,169|176,182|184,199|201,210|212,214|216,224|235,235|238,239|244,248|255,258|261,261|263,263|265,270|276,280|285,290|292,298|300,301|305,309|312,313|315,326|328,330|332,354|357,362|364,364|373,373|377,382|384,385|388,390|393,396|398,409|444,444|448,449|463,466|468,469|476,484|486,487|493,493 S??EEEEEEETTTTEEEEEETTS?EEEEEEEE--------------????????????????????S??GGGS-S?SEEE?GGG??TT?SEE--EEEEEEE???-S?SEEEEEE?BTSEEEEEETTSEEEEEET-TTTEEEEE-EEGGG----------T?SS????EEE------EEEEEEE?TTSSSEEEEEEEEETT-SEEEEEEEEE?GGG?EEEEEEEEE----------E??SS????EEEEE------ETTT??B?B?BHHHHH-----GGGGT????EEEEEE?SSEEEEE?TT???EEEEE?-SS?EEEEEEEEEEEE?SSS?EEEEEEEEEEETTSEEEEEETTT??EEEEEE?S--------S???HHHHTT?EE-?TTS?-EEEE?SSSEEEEEEEES????---------------------?---?????B???TT????????---??TTTS?SS-?????HHHHHHHHH?TT?-???S 2OAJ|A PF08597.5_eIF3_subunit_seed 40 338 !Q:0,198|202,206|222,222|227,228|230,230|238,238|252,252|273,337 Q:199,201|207,221|223,226|229,229|231,237|239,251|253,272 -?--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------???TTT?-???SHHHHHHHHHHHHHH-HGGG--T-TSTTHHH-HHHHHHHHHHTTS?HHHHHHHHHHHHHHHHHHHH??????---------------------??------------------------------------ 3BPJ|A PF08601.5_PAP1_seed 10 478 !Q:0,69|71,401|403,413|416,417|420,421|424,424|435,435|437,440|443,444|456,457|464,464 Q:70,70|402,402|414,415|418,419|422,423|425,434|436,436|441,442|445,455|458,463|465,477 ??-------------------------------------------------------------------?S-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------??------------------------------------------------------------------------------------------------------------------????S???????????SS??SS??EE?HHHHHHHHHT?S??--SS??HHHHHHHHTTT??EETTEE?EEHHHHHHHHHSS 1SSE|A PF08603.6_CAP_C_seed 35 186 !Q:0,7|12,12|22,22|25,31|35,38|41,41|48,48|51,51|58,58|68,68|87,87|97,98|106,106|113,114|117,117|119,120|122,123|130,130|138,139|142,145|151,151|156,158|165,167|169,174|183,185 Q:8,11|13,21|23,24|32,34|39,40|42,47|49,50|52,57|59,67|69,86|88,96|99,105|107,112|115,116|118,118|121,121|124,129|131,137|140,141|146,150|152,155|159,164|168,168|175,182 --??----EEEE-ETTEEEEES?BS??----?EEE????TT?EEEEES?BS?EEEEEE-EESEEEEES?EEEEEEEEEESSEEEEES?EEEEEEESS??SEEEEES?EEEEEE??TT?T--T?-EEEEES?EEEEEEE--EE----TTTEE-EEEE???EEEEEE--?S------SSEEEEEE??? 2B0R|A PF08608.7_Wyosine_form_seed 72 82 !Q:2,3|11,27|32,33|38,41|51,54|56,56|58,61|63,64 Q:0,1|4,10|28,31|34,37|42,50|55,55|57,57|62,62|65,81 HH??SEEEEEE??--??????---????GGGS??HHHH----HHHHHHHHT----T?T----T--EEEEEEEGGGTEEEEEE 2YX0|A PF08612.6_Med20_seed 32 449 !Q:0,1|6,20|26,27|30,35|48,48|65,67|70,70|72,93|96,98|105,105|109,109|124,164|169,169|178,179|181,184|211,211|215,219|234,236|249,343|361,368|370,371|373,373|378,393|395,398|403,435|442,442|448,448 Q:2,5|21,25|28,29|36,47|49,64|68,69|71,71|94,95|99,104|106,108|110,123|165,168|170,177|180,180|185,210|212,214|220,233|237,248|344,360|369,369|372,372|374,377|394,394|399,402|436,441|443,447 ??EEEE---------------EEESS??TT------HHHHHHHTTTSS?SEEEEEEEEEEEEEEE???SS?T----------------------TS???EEEEEE?SSS?EEEEEETTEEEEEE---------------------------------------??GGGS?HHHHHTTS??S????HHHHHHHHSTTTEEEEEEEEEEEEEE-EEE-----TTEEEEEEEEEETT---EEEEEEEEEEES?---------------------------------------------------------------------------------------------?TTHHHHHHHHHHHHHHT--------T??S?EEES--------------??S????SSHH---------------------------------HHHHHH-HHHHT? 4GWQ|F PF08613.6_Cyclin_seed 9 265 !Q:19,32|34,69|71,72|75,140|143,143|153,162|167,168|170,174|190,200|202,202|205,207|228,228|231,234|245,245|263,264 Q:0,18|33,33|70,70|73,74|141,142|144,152|163,166|169,169|175,189|201,201|203,204|208,227|229,230|235,244|246,262 HHHHHHHHHHHHHHHHHHH??????????????T------------------------------------T??SS?----------------------------------------------------------------?SS?HHHHHHHHH----------HHHT??H-----HHHHHHHHHHHHHHH-----------H?TT???STTTHHHHHHHHHHHHHHHH?SS???-HHHHHHHHTS?HHHHHHHHHHHHHHTTT?? 2PK9|B PF08614.6_ATG16_seed 16 229 !Q:0,129|139,148|226,228 Q:130,138|149,225 ????????????????-??????????-------------------------------------------------------------------------------------------------??????HHHHHHHHH----------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??? 3A7P|A PF08615.6_RNase_H2_suC_seed 43 448 !Q:0,1|10,15|17,17|20,22|30,83|85,85|88,88|92,149|166,167|169,169|178,368|377,378|382,419|425,429|432,432 Q:2,9|16,16|18,19|23,29|84,84|86,87|89,91|150,165|168,168|170,177|369,376|379,381|420,424|430,431|433,447 ??EEESSEES------S?EE??-HHHHTTT------------------------------------------------------T?EE?SSS----------------------------------------------------------EEEEETTEEEEEEEEE??T-TEEEEEEE???????????-----------------------------------------------------------------???????????????????????-------------------------------------------------------------------------------------------?EEEEEESE--EEE--------------------------------------EEESS??--?TT?HHHHHHSHHHHHHHH 3P56|C PF08617.5_CGI-121_seed 46 294 !Q:3,3|5,5|7,16|27,27|29,49|54,54|58,77|79,79|93,108|114,116|130,130|134,134|144,145|148,149|159,186|189,191|195,195|203,226|230,231|233,235|239,240|250,251|254,278 Q:0,2|4,4|6,6|17,26|28,28|50,53|55,57|78,78|80,92|109,113|117,129|131,133|135,143|146,147|150,158|187,188|192,194|196,202|227,229|232,232|236,238|241,249|252,253|279,293 EES?S?H----------HHHHHHHHHT?S--------------------?SEEE?GGG-------------------?S?HHHHHHHHHHHHH----------------HHTTT-??SSSSHHHHHHHHH?SSS?HHHHHHHHB??TT-?SEEEEEEEE---------------????-----????HH---HHT-TSSSEEE-----------------------?GGG--G---GGT??HHHHHHHHT??SS?----------------------??HHHHHHHHHHHHHHS 3ENH|C PF08623.5_TIP120_seed 23 233 !Q:7,18|31,32|39,41|45,46|68,72|74,74|78,82|87,87|98,99|114,121|125,125|133,136|139,148|160,164|168,168|190,190|194,200|203,206|208,220|232,232 Q:0,6|19,30|33,38|42,44|47,67|73,73|75,77|83,86|88,97|100,113|122,124|126,132|137,138|149,159|165,167|169,189|191,193|201,202|207,207|221,231 GGTTTTH------------HHHHHHHHHTTS??STTEEE???SSS??EEEGGGHHHHHHHHHHHHHHH-----H?GGG??---HHHH-HHHHHHTTSS-?HHHHHHHHHHHHHH--------HHH?HHHHHHH----GG----------GGTHHHHHHHH-????TTS?HHHHHHHHHHHHHHHHHHHHH-HSS-------SS????H-------------HHHHHHHHHTT? 4A0C|A PF08630.5_Dfp1_Him1_M_seed 21 167 !Q:3,8|13,13|18,18|27,27|36,37|42,42|45,72|77,79|89,166 Q:0,2|9,12|14,17|19,26|28,35|38,41|43,44|73,76|80,88 TSH------HHHH-HHTT?EEEEHHHH-HHHHHHTT??HHHH?SS?---------------------------SSTT???HHHHHHHHH?????????--------------------------------------------------------------------- 3QBZ|A PF08644.6_SPT16_seed 32 188 !Q:0,0|37,37|40,40|46,47|49,50|52,59|61,62|64,65|68,69|72,72|84,84|88,98|115,187 Q:1,36|38,39|41,45|48,48|51,51|60,60|63,63|66,67|70,71|73,83|85,87|99,114 ?EEEGGGTEEEEEETTEEEEEEGGGEEEEEEEEETTE-EE-EEEEE??T--T???--???S??S--SS?-TT?EEEEEEEEEES?HHH-----------HHHHHHHHHHHHHHHH??--------------?----------?-----------------------??-------------------- 4KHB|A PF08645.6_PNK3P_seed 32 331 !Q:0,0|2,3|7,7|15,15|18,18|20,20|23,23|25,25|27,36|39,40|43,45|47,47|50,55|64,64|69,80|88,88|94,107|111,115|131,134|137,143|149,149|151,151|153,194|196,200|220,223|225,228|231,232|234,237|241,241|243,245|247,247|249,286|290,300|304,304|306,307|309,310|321,322|325,325 Q:1,1|4,6|8,14|16,17|19,19|21,22|24,24|26,26|37,38|41,42|46,46|48,49|56,63|65,68|81,87|89,93|108,110|116,130|135,136|144,148|150,150|152,152|195,195|201,219|224,224|229,230|233,233|238,240|242,242|246,246|248,248|287,289|301,303|305,305|308,308|311,320|323,324|326,330 ?E--EEE?SBTTTEE?SS-S?SS?S-S----------TT??EE---S?TT------HHHHHHHH-HHHT-----------?EEEEEEE?HHHHH--------------TSS----?HHHHHHHHHHHHHHH----TS?-----?EEEEE?S-S------------------------------------------S-----SSSTTSTHHHHHHHHTSSS----S????GG--G?---EEE?S???B?T--------------------------------------TSB-----------TTB?S??S??HHHHHHHHHT??EE?HHHHT 2FPR|A PF08646.5_Rep_fac-A_C_seed 33 200 !Q:11,17|19,19|26,27|30,40|42,44|46,46|50,50|53,63|66,76|89,90|101,101|104,104|120,120|123,123|133,136|138,138|152,152|162,177|186,188|190,191 Q:0,10|18,18|20,25|28,29|41,41|45,45|47,49|51,52|64,65|77,88|91,100|102,103|105,119|121,122|124,132|137,137|139,151|153,161|178,185|189,189|192,199 EEEEEEEEEEE-----??S-TTEEEB??ST-----------T???B?EEE-TT-----------TE-----------EEETTTTEEESS??EEEEEEEEEE?SS?EEEEEEEHHHHHHHH-SS?HHHHHHHTT----S?HHHHHHHHHHTTT?EEEEEEEEE?????------?????EEEEEEEE---E??HHHHHHHH 1L1O|C PF08652.6_RAI1_seed 31 100 !Q:0,1|6,33|45,55|57,59|61,61|67,68|82,83|91,91|94,94 Q:2,5|34,44|56,56|60,60|62,66|69,81|84,90|92,93|95,99 ??EESS-???????????????????????????SGGGEEEEEEE?-------???T---T?HHHHH--HHHHHHHHHHHHT??EEEEEEE?TT?BEEEE 3FQJ|A PF08659.5_KR_seed 85 257 !Q:11,13|24,24|26,29|32,33|43,43|45,57|65,69|71,82|85,88|94,94|96,96|98,102|109,112|115,115|123,125|130,130|134,138|145,150|152,155|159,160|185,191|193,194|206,206|209,210|212,213|215,215|237,245|251,252 Q:0,10|14,23|25,25|30,31|34,42|44,44|58,64|70,70|83,84|89,93|95,95|97,97|103,108|113,114|116,122|126,129|131,133|139,144|151,151|156,158|161,184|192,192|195,205|207,208|211,211|214,214|216,236|246,250|253,256 SEEEEETTTSH---HHHHHHHHHH-H----TT-?SEEEEEESS-G-------------GGSTTHH-----H------------HH----HHHHH-T-T?----EEEEEE??--TT?HHHHHHH---HHTS?SSS----?EEEEEE??????S??-?TTT??HHHHHHHHHTTHHHHHHHHHHHTT-------S??SEEEEEEEGGG-TT??T--T?HHHHHHHHHHHHHHHHHHHTT??------?EEEEE??BSSS 1NXQ|A PF08661.6_Rep_fac-A_3_seed 22 141 !Q:0,3|7,8|12,12|20,27|30,30|42,42|52,52|56,68|77,78|81,83|87,87|94,94|98,98|101,103|110,113|117,121|135,135|137,137 Q:4,6|9,11|13,19|28,29|31,41|43,51|53,55|69,76|79,80|84,86|88,93|95,97|99,100|104,109|114,116|122,134|136,136|138,140 ????TTS??EEE?GGGTTTS--------TT?EEEEEEEEEEE?TTSSEEEEE?TTS?------------EEEEEESS??SS???SEE-EEEEEE?TTS?EE---EEEEEE??-?SSS--???HHHHHHHHHHHHH?G-GGS 1L1O|A PF08662.6_eIF2A_seed 22 223 !Q:4,4|6,9|13,13|23,23|25,37|47,53|56,56|64,64|68,70|77,77|82,83|89,90|95,96|103,106|109,112|120,125|130,130|134,134|140,143|146,146|148,148|152,152|158,159|165,167|170,170|177,177|185,185|190,194|197,197|213,215|218,218 Q:0,3|5,5|10,12|14,22|24,24|38,46|54,55|57,63|65,67|71,76|78,81|84,88|91,94|97,102|107,108|113,119|126,129|131,133|135,139|144,145|147,147|149,151|153,157|160,164|168,169|171,176|178,184|186,189|195,196|198,212|216,217|219,222 EEEE?T????EEE?TTSSEEEEE?T-------------TSEEEEEET-------TT?SEEEEEE?SSS-?-EEEEEE?TTSS--EEEEE--ETTS-?EEEEET----TT----TEEEEEE??????EEEE?TTS?EEEEE---?TT-S?EEE-EETTT??EEEEE???SS?EEEEEE?TTSSEEE-EEET-----TS?EEEEETTTTEEEEEE???SS?EEEE 2O9K|A PF08666.7_SAF_seed 169 96 !Q:0,0|8,10|12,12|15,15|19,25|33,33|36,36|38,38|41,41|47,47|49,49|52,61|72,77|82,82|84,84|87,87|96,96 Q:1,7|11,11|13,14|16,18|26,32|34,35|37,37|39,40|42,46|48,48|50,51|62,71|78,81|83,83|85,86|88,95 ?SEEEESS?--B?TT?EEE-------ETTEEEE?SS?B?TT?EEESS?B?TT?---------EEEETTEEEE------EESS?B?TT?EESTTTEE- 1B7J|A PF08668.7_HDOD_seed 57 223 !Q:0,4|15,15|17,17|20,21|32,32|50,51|55,58|66,66|89,95|98,98|121,126|128,128|130,131|133,134|170,173|185,185|189,197|208,209|221,221 Q:5,14|16,16|18,19|22,31|33,49|52,54|59,65|67,88|96,97|99,120|127,127|129,129|132,132|135,169|174,184|186,188|198,207|210,220|222,222 ?????HHHHHHHHHT-T?TT??HHHHHHHHTT?HHHHHHHHHHHHSHHHH--TTS???-SHHHHHH-HHHHHHHHHHHHHHHHHHHHHS??----?SS?HHHHHHHHHHHHHHHHHHHHHT------T?S?-H--HHHHHHHHTTTHHHHHHHHHSHHHHHHHHHHHHHH??-?HHHHHHHHHSS?HHH---------HHHHHHHHTT??HHHHHHHHHTT?G 3M1T|A PF08669.6_GCV_T_C_seed 190 196 !Q:1,2|9,10|16,16|18,32|39,57|61,61|64,68|71,71|76,91|94,98|110,110|114,115|124,125|127,138|142,142|145,145|147,150|153,153|157,157|159,179|182,183|191,192|194,194|196,196 Q:0,0|3,8|11,15|17,17|33,38|58,60|62,63|69,70|72,75|92,93|99,109|111,113|116,123|126,126|139,141|143,144|146,146|151,152|154,156|158,158|180,181|184,190|193,193|195,195 S??TTHHHH--HHHHH-H------?----??--EEEEEE-------------------EES-SS-????TT?EEEE----------------TT-----EEEEEEEEEEE?TTT-?SEEEEEEE--E------------GGG?ST-T?---EE-EEE-E---------------------TT--EEEEEEE--E?S- 1WOP|A PF08671.5_SinI_seed 17 30 !Q:0,1|16,17|28,29 Q:2,15|18,27 ??HHHHHHHHHHHHTT??HHHHHHHHHH?? 1B0N|A PF08672.6_APC2_seed 18 64 !Q:9,9|11,11|26,26|30,32|35,36|55,56 Q:0,8|10,10|12,25|27,29|33,34|37,54|57,63 HHHHHHHHH?S-EEHHHHHHHHHHHS?GGG-??TT??HHHHHHHHHHHHHTTSEE??TTTEEEE 1LDD|A PF08673.5_RsbU_N_seed 14 83 !Q:14,15|21,21|35,36|52,52|56,61|82,82 Q:0,13|16,20|22,34|37,51|53,55|62,81 HHHHHHHHHHHHHH??HHHHH-HHHHHHHHHHHTT??HHHHHHHHHHHHHHH?TTS-----?HHHHHHHHHHHHHHHHHHHH? 2J6Z|A PF08674.5_AChE_tetra_seed 6 38 !Q:20,37 Q:0,19 HTTTHHHHHHHHHHHHHHHH?????-???????????? 4BDT|A PF08675.6_RNA_bind_seed 2 87 !Q:0,0|2,5|7,7|15,16|19,20|34,34|39,39|48,48|50,50|64,64|67,67|79,85 Q:1,1|6,6|8,14|17,18|21,33|35,38|40,47|49,49|51,63|65,66|68,78|86,86 ?S????S?TTEEEEE??TT??HHHHHHHHGGGSS?EEEE?SSSEEEEE?S?HHHHHHHHHHGGG?SS?EEEEHHHHHHT???????S 3D45|A PF08676.6_MutL_C_seed 108 204 !Q:1,5|7,7|12,16|28,30|34,34|45,49|58,58|62,63|70,79|90,90|92,94|113,113|117,122|137,138|140,140|142,144|158,178|191,191|195,195|198,203 Q:0,0|6,6|8,11|17,27|31,33|35,44|50,57|59,61|64,69|80,89|91,91|95,112|114,116|123,136|139,139|141,141|145,157|179,190|192,194|196,197 T-----T?EEEE-----EETTTEEEEEE---TTE-EEEEEHHHHH-----HHHHHHHH-HHH--HHHHSS--------??EEEEEEEEEE-E??-HHHHHHHHHHHHHHHHTT?EEE?----?STTEEEEEEEETTS??S?H---HHHHHHHHHHHTT??-----????--------??TTHHHHHHHHTT?SSS?SS---??? 3NCV|A PF08677.5_GP11_seed 8 249 !Q:0,12|19,25|28,30|32,38|43,43|46,48|56,57|59,59|73,76|86,88|90,91|93,95|105,107|111,111|114,114|131,131|160,161|164,164|175,183|190,203|212,213|215,217|219,219|229,230|233,233|236,236|239,240|247,248 Q:13,18|26,27|31,31|39,42|44,45|49,55|58,58|60,72|77,85|89,89|92,92|96,104|108,110|112,113|115,130|132,159|162,163|165,174|184,189|204,211|214,214|218,218|220,228|231,232|234,235|237,238|241,246 ?????????????SGGGSB?--?-??TT???B-------TTTB?TT???HHHHTTT??S?BHHHHHHHHHHHH-???TTBEEEESS???S??B??-EEEEEEEEB???TTS?TT?EEEEEETTEEEEEETT?BHHHHHHHHHHHHHHHHHTTSSEEEEEE?-SS?TTEEEEEESS????-????EEETTE--------------EEEEEEEE??B???S?EEEEEEEEE??TT?SS?EE--EEEEEE?? 1TJA|F PF08678.5_Rsbr_N_seed 9 134 !Q:24,24|26,29|46,47|49,49|52,52|72,73|95,103|105,106|133,133 Q:0,23|25,25|30,45|48,48|50,51|53,71|74,94|104,104|107,132 HHHHTHHHHHHHHHHHHHHHHTTS-S????HHHHHHHHHHHHHHHH--T?SS?TTTTHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHHHHHT??--?????H--HHHHHHHHHHHHHHHHHHHHHHHHHH? 2BNL|A PF08679.6_DsrD_seed 13 74 !Q:11,13|21,21|31,35|39,39 Q:0,10|14,20|22,30|36,38|40,73 HHHHHHHHHHS---SHHHHSS?EEHHHHHHH----?TTS?HHHHHHHHHHHHHTTSEEEEEETTEEEEEETTHH 1UCR|A PF08680.5_DUF1779_seed 14 229 !Q:6,22|32,34|36,37|51,51|54,54|57,58|62,64|89,89|94,94|97,98|110,112|114,114|133,135|145,147|152,152|165,173|183,184|189,190|198,198|200,200|207,215|223,228 Q:0,5|23,31|35,35|38,50|52,53|55,56|59,61|65,88|90,93|95,96|99,109|113,113|115,132|136,144|148,151|153,164|174,182|185,188|191,197|199,199|201,206|216,222 TEEEEE-----------------EEEEEEEEE???H--HHHHHHHHHHHHH?TT?EE--EEE??-SSEEEEEEEEEETTTTEEEEEEEE-EESS?SS??EEEEEEEEESS-??S?HHHHHHHHHHHHHHHHSS???EEEEEEEEE???HHHH-HHHHHHHHHHHH?????????BTTEEEEEE??TTSS??EEETTEE-E?EEEEEE??-??????EEEEESS?????? 2FPN|A PF08681.6_DUF1778_seed 45 94 !Q:0,0|5,6|22,22|24,24|47,49|62,62|67,70|83,93 Q:1,4|7,21|23,23|25,46|50,61|63,66|71,82 ?EEEE??HHHHHHHHHHHHHTT?S?HHHHHHHHHHHHHHHHHHHHHH---HHHHHHHHHHHH-HHHH?---HHHHHHHHHHHH?------???? 1Y9B|A PF08682.5_DUF1780_seed 2 208 !Q:0,0|23,23|41,44|50,51|56,56|72,104|132,133|137,137|145,145|155,159|167,167|174,174|184,184|188,188|197,198|201,202|206,207 Q:1,22|24,40|45,49|52,55|57,71|105,131|134,136|138,144|146,154|160,166|168,173|175,183|185,187|189,196|199,200|203,205 ?HHHHHHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHTT????GGGEE??SSSS?SEEETTEEEEEEEEE?????????????????????????????????EEEEHHHHHHTTHHHHHHHHHHHHHHT??GGG?EEEEEEE?SSEEEETTS?????HHHHHTT?SEEEEE?SSEEEEEEE?TTS?HHHHTTTT??EE??TTT?? 1Y0K|A PF08683.6_CAMSAP_CKK_seed 14 142 !Q:0,14|28,28|42,43|49,53|55,55|62,63|67,67|76,77|82,82|91,93|97,97|117,118|123,124|127,127|133,133|139,139|141,141 Q:15,27|29,41|44,48|54,54|56,61|64,66|68,75|78,81|83,90|94,96|98,116|119,122|125,126|128,132|134,138|140,140 ?????-?????????HHHHHHHHHHTTT?SSTTHHHHHHHHH--HHHHS?---?S?EEEEES--SSS?SEEEEEEE-?TTSS?EEEEESSS--?SEE?TTTEEEEEEEETTTTEEEE?-SSSS??TT?SEEEE?STTTS?S? 1UGJ|A PF08684.5_ocr_seed 3 101 !Q:0,4|25,27|31,31|44,45|59,60|63,63|70,72|74,74 Q:5,24|28,30|32,43|46,58|61,62|64,69|73,73|75,100 ?????HHHHHHHHHHHHHHHHHHTT???GGG?HHHHHHHHHHHS??SHHHHHHHHTSTT??SS?SSGGGS???S?HHHHHHHHHHHHHHHHHHHTHHHHHH 2Y7C|D PF08687.6_ASD2_seed 14 385 !Q:0,131|171,201|212,212|252,256|266,269|303,303|312,350|383,384 Q:132,170|202,211|213,251|257,265|270,302|304,311|351,382 --??-----------????--------------------------------------------------------------------------------------?----------------------????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-------------------------------HHHHHHHHHS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----HHHHHHHHH----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS?HHHHHHHH---------------------------------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?? 3THF|A PF08694.6_UFC1_seed 9 184 !Q:10,17|20,20|22,22|48,50|55,55|57,57|61,61|84,85|92,95|97,97|104,104|108,108|114,116|130,131|140,160|177,177|179,180 Q:0,9|18,19|21,21|23,47|51,54|56,56|58,60|62,83|86,91|96,96|98,103|105,107|109,113|117,129|132,139|161,176|178,178|181,183 HHHHHHHTTS????????TT?T-HHHHHHHHHHHHHHHHHHHHHHHTT???EEEE-E?TTS?EEEEEEEEEETTEEEEEEEEEE??TTTTTS????B?GGGTTT?SSB?TTSBB???TTHHHHHHHHTTS??HHHHHHHT---------------------HHHHHHHHHHHHHHHT?S??SEE 2Z6O|A PF08699.5_DUF1785_seed 46 86 !Q:7,7|9,22|25,32|37,37|51,59|61,66|70,70|84,85 Q:0,6|8,8|23,24|33,36|38,50|60,60|67,69|71,83 EEETTEE-E???-----------SS?-----??EEET-TEEEEEEEEEEEE---------E?-----SSS-EEEEEEEEEEEEE?? 4KRE|A PF08702.5_Fib_alpha_seed 20 151 !Q:0,12|14,14|18,18|35,35|67,67|71,74|77,78|87,87|137,137|139,140|144,149 Q:13,13|15,17|19,34|36,66|68,70|75,76|79,86|88,136|138,138|141,143|150,150 ?????????????S?EEE?SHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?TTT??-?TT-?HHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS?S??EES?--???S 2Z4E|A PF08703.5_PLC-beta_C_seed 8 197 !Q:2,2|4,7|90,92|177,188|190,197 Q:0,1|3,3|8,89|93,176|189,189 SS?H----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH------------H??????-- 1JAD|A PF08704.5_GCD14_seed 7 291 !Q:4,6|12,13|16,24|37,38|41,41|47,48|65,65|71,73|89,92|95,95|101,103|106,107|109,111|113,117|125,126|128,128|141,142|177,182|185,192|196,251|254,275|277,281|283,283 Q:0,3|7,11|14,15|25,36|39,40|42,46|49,64|66,70|74,88|93,94|96,100|104,105|108,108|112,112|118,124|127,127|129,140|143,176|183,184|193,195|252,253|276,276|282,282|284,290 EEEE???HHHHH--HT?????????HHHHHHHHHHTT??TT?EEEEE??TTSHHHHHHHHHTTTT?EEEEE???HHHHHHHHHHHHHTT?---GG-GEEEE???GG--G??-S??---SEEEEEE??S?GGGTHHHHHHHE--EEEEEEEEEESSHHHHHHHHHHHHHSSEEEEEEE??????EE------??TTS-------------------------------------------------------?EE?---------------------S?????S?EEEEEEE 1I9G|A PF08705.6_Gag_p6_seed 130 97 !Q:0,17|19,22|24,39|44,44|49,52|55,55|57,57|59,60|62,66|68,74|76,84|87,92|97,97 Q:18,18|23,23|40,43|45,48|53,54|56,56|58,58|61,61|67,67|75,75|85,86|93,96 ?????-------?-----S?---S??-?------------SSTT-TGGG----SS?S?S--S-----S???----S---------SS------SSTT- 2C55|A PF08708.6_PriCT_1_seed 93 96 !Q:0,11|23,23|28,28|36,46|49,49|66,66|68,73|76,78|96,96 Q:12,22|24,27|29,35|47,48|50,65|67,67|74,75|79,95 -------?????HHHHHHHHHHH-HHHH-HHHTTTT?--------??HH-HHHHHHHHHHHHHHHH-S------SS???HHHHHHHHHHHHHHHHH- 3VW4|A PF08709.6_Ins145_P3_rec_seed 19 256 !Q:0,3|5,5|9,9|20,30|35,35|39,41|49,50|54,58|60,61|70,70|73,76|84,98|125,125|127,127|131,131|135,135|153,153|168,170|173,174|176,176|187,187|192,192|196,196|206,213|215,216|219,219|225,225|228,228|231,232|240,242|251,251 Q:4,4|6,8|10,19|31,34|36,38|42,48|51,53|59,59|62,69|71,72|77,83|99,124|126,126|128,130|132,134|136,152|154,167|171,172|175,175|177,186|188,191|193,195|197,205|214,214|217,218|220,224|226,227|229,230|233,239|243,250|252,255 ????B?BTT?EEEEEEETTS?---------?EEEE?TTT???EEEETTS??SSS?---?S-?GGGSEEEE-EE????HHHHHHT??--???????????STHHHHHHHHHHHHHHHHHHHHHTTT?B?BTT?EEE-EEETTTTEEEEEEEEEE?SSSTTSEEEEEESS??-GG--G?EEEEESSTTS?TTSB?BTT?EEEEEESSS?-------S?-EE-EEEEE?SS?TT?-EEEEESS???EEEEEEEE?HHHH 3IM7|A PF08710.5_nsp9_seed 9 113 !Q:0,2|4,8|22,22|33,33|38,38|47,47|49,51|57,57|62,62|69,71|77,78|81,82|93,94|110,110|112,112 Q:3,3|9,21|23,32|34,37|39,46|48,48|52,56|58,61|63,68|72,76|79,80|83,92|95,109|111,111 ???B?????EEEEEEEESSSTT?EEEEEEEEEE?TTTS?EEEEEEES?S???EEEEE?SSSS?EEEEEB???EEEEE??TT??EEEEEEEBTT??HHHHHHHHHHHHHHS?B? 3EE7|A PF08711.6_Med26_seed 76 75 !Q:8,9|11,20|28,28|40,53|67,68|74,74 Q:0,7|10,10|21,27|29,39|54,66|69,73 HHHHHHHT--S?-??------HHHHHHT?HHHHHHHHHHH-----------???SHHHHHHHHHHHH--HHHHT? 3NFQ|A PF08712.6_Nfu_N_seed 107 101 !Q:0,0|2,2|5,6|8,8|16,17|20,20|25,30|32,32|35,35|43,47|55,55|79,80|93,93 Q:1,1|3,4|7,7|9,15|18,19|21,24|31,31|33,34|36,42|48,54|56,78|81,92|94,100 ?E-EE??S?TTEEEEE?-SS?SSSS?--?--E-EE?STTGGGG----?HHHHHHT-TSTTEEEEEEETTEEEEEESSTT??HHHHHHHHHHHH-HHHHHHT 2FFM|A PF08713.6_DNA_alkylation_seed 89 289 !Q:8,15|28,34|39,43|59,65|82,82|98,99|102,107|110,124|135,136|139,140|159,159|161,171|185,186|200,200|204,213|227,233|251,252|263,270|272,277 Q:0,7|16,27|35,38|44,58|66,81|83,97|100,101|108,109|125,134|137,138|141,158|160,160|172,184|187,199|201,203|214,226|234,250|253,262|271,271|278,288 HHHHHHHT??------HHHHHHHHHHTT-------TSSB?????HHHHHHHHHHHHHHH???---?GGGHHHHHHHHHHSSB-HHHHHHHHHHHHHTG--GG----??GG---------------GHHHHHHHHH--SS??HHHHHHHTTTHHHHHHHH?G-----------GGHHHHHHHHHHT??HHHHHHHHHTTTT?GGG--------??HHHHHHHHHHHTT??----?HHHHHHHHHHHHHHHTT-?HHHHHHHHHH--------S?---??HHHHHHHHTTT 3L9T|A PF08714.6_Fae_seed 45 184 !Q:6,7|10,18|20,20|44,45|50,51|54,54|62,62|73,75|105,105|119,128|131,141|164,164|166,166|177,179|183,183 Q:0,5|8,9|19,19|21,43|46,49|52,53|55,61|63,72|76,104|106,118|129,130|142,163|165,165|167,176|180,182 EEEEEE??GG---------G?EEEEEEEEETTSHHHHHHHHHHH??BTTB??EE?EEETTEE?SSEEEEEESS???SHHHHHHHTTHHHHHHHHHHHHHHHTTSS?TTTGGGEEEEEEE-------???TT?--------??HHHHHHHHHHHHHHHHHHHHTT?S?HHHHHHHGGG???TTS? 1Y60|A PF08715.5_Viral_protease_seed 5 331 !Q:0,3|15,15|21,21|25,25|40,40|43,46|49,49|52,52|57,59|70,72|75,78|96,98|105,109|126,128|145,146|159,160|164,166|179,180|183,183|189,189|199,199|212,212|215,215|217,217|224,224|252,255|267,267|276,276|282,282|285,285|318,318|323,330 Q:4,14|16,20|22,24|26,39|41,42|47,48|50,51|53,56|60,69|73,74|79,95|99,104|110,125|129,144|147,158|161,163|167,178|181,182|184,188|190,198|200,211|213,214|216,216|218,223|225,251|256,266|268,275|277,281|283,284|286,317|319,322 ????EEEEEESSSSS?EEEEE?TTS?HHHHTSSEEETTEE?SS????TT?TT?EEEE???SHHHHHHHHH---HH????TTHHHHHHHHHHHHTTS???EETTEE?????TTTHHHHHHHHHHTTS???BSSHHHHHHHHHHTTT??HHHHHHHHHHTT??TTS???HHHHHHHHHTTB??TT?EEEEE-EEETTTEEE-EEEEETHHHHEE-ES?S?HHHHHH?EEEEETTTEEEEEEEEEEESSEEEEEE----EEEEEEEETTS?SEEEEEEE?SSSEE-EE-EEEESSSEEEEETTEEEEESEEEEEEEEEEEE?SEEE????---- 3MP2|A PF08716.5_nsp7_seed 7 89 !Q:2,5|7,9|21,22|63,64|67,72|88,88 Q:0,1|6,6|10,20|23,62|65,66|73,87 SS????S???HHHHHHHHTTT??TTSTHHHHHHHHHHHHHTSSSSHHHHHHHTTTHHHHHHHT??ST------HHHHHHHHTHHHHTT? 2KYS|A PF08717.5_nsp8_seed 9 210 !Q:0,42|48,48|51,52|74,76|78,79|102,103|117,117|122,125|129,129|136,136|164,164|168,168|170,171|175,175|179,183|189,189|191,191|199,209 Q:43,47|49,50|53,73|77,77|80,101|104,116|118,121|126,128|130,135|137,163|165,167|169,169|172,174|176,178|184,188|190,190|192,198 ???????????????????????????---?????-???????TTTTT?SS??STTTHHHHHHHHHHHHHHHTT???S??HHHHHHHHHHHHHHHHHHHHHH??HHHHHHHHHHHTT?EESS????STT?EEEEEE?SHHHHHHHEETTEEEETTEEEEEEEEE?TTS?B??GGG?STT-----TGGGS?S?EEEEEEE--????-???? 2AHM|E PF08718.6_GLTP_seed 68 259 !Q:0,2|20,28|31,34|51,51|58,58|61,61|65,95|118,134|145,153|155,162|164,164|178,185|187,189|195,196|212,213|222,230|236,246|255,258 Q:3,19|29,30|35,50|52,57|59,60|62,64|96,117|135,144|154,154|163,163|165,177|186,186|190,194|197,211|214,221|231,235|247,254 ???BHHHHHHHHTTSGGGGG---------GG---?SGGGHHHHHHHHHHHH-HHHHHH-HH?TTT-------------------------------TSBHHHHHHHHHHHHGGGTTSS-----------------HHHHHHHHHH---------H--------H-HHHHHHHHHHHHT--------T???TTSTT??HHHHHHHHHHHTGGG??HHHHHHHH---------HHHTT??--------?HHHHHHHH???? 4GH0|A PF08719.6_DUF1768_seed 80 333 !Q:3,4|8,13|23,26|28,38|41,45|47,56|58,64|67,69|76,83|91,96|98,99|101,140|144,146|151,160|167,181|184,185|189,193|195,195|199,199|218,220|222,238|240,242|251,254|262,263|266,271|275,275|279,311|313,313|315,315|327,327 Q:0,2|5,7|14,22|27,27|39,40|46,46|57,57|65,66|70,75|84,90|97,97|100,100|141,143|147,150|161,166|182,183|186,188|194,194|196,198|200,217|221,221|239,239|243,250|255,261|264,265|272,274|276,278|312,312|314,314|316,326|328,332 EEE??TTS------GGGTTSTTS???-E-----------EE-----T----------T-------EE---ESSHHH--------HHHHHHB??----H--H----------------------------------------HHH---HHHH--??-----?HHHHHH---------------HH??SSS?----B?TTH-HHHHHHHHHHHHHHHHHS--?H-----------------H---HHHHHHHT----TTEEEEE??SS?----?SSS?TTT---------------------------------T?S?THHHHHHHHHH-HHHHH 2B3W|A PF08720.5_Hema_stalk_seed 3 175 !Q:0,4|8,9|16,16|20,21|28,29|32,32|34,36|39,40|65,71|75,75|77,77|79,80|125,125|129,132|138,140|145,145|155,158|160,174 Q:5,7|10,15|17,19|22,27|30,31|33,33|37,38|41,64|72,74|76,76|78,78|81,124|126,128|133,137|141,144|146,154|159,159 ?????SSS??TTSEEE?TTS??EEEEEE??TT?S???EE??TTTHHHHHHHHHHHHHHHHHHHHT???????EEE?S?S??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?TTT????STTEE???TTTS?HHHHHHHTT????S??????????????? 1FLC|B PF08721.6_Tn7_Tnp_TnsA_C_seed 38 99 !Q:2,4|17,23|32,37|49,50|65,74|76,77|96,97 Q:0,1|5,16|24,31|38,48|51,64|75,75|78,95|98,98 GS--?HHHHHHHHHHTS???????HHHHHTHH------HHHHHHHHTTT--SBHHHHHHHHHHHH----------T??TTHHHHHHHHHHHTTSEE??T 1F1Z|A PF08722.6_Tn7_Tnp_TnsA_N_seed 76 155 !Q:11,12|14,32|44,47|50,57|62,65|78,84|93,102|108,111|113,116|126,135|138,138|144,144|147,148|153,153 Q:0,10|13,13|33,43|48,49|58,61|66,77|85,92|103,107|112,112|117,125|136,137|139,143|145,146|149,152|154,154 TTEEEEEEEEE??H-------------------HHHHHHHHHHT????EE--------TTEE-???EEEEEEEESSSS-------SSEEEEEE??--------GGGGG----S----HHHHHHHHH----------HH-HHHHH-TT??EEEE?G 1F1Z|A PF08723.5_Gag_p15_seed 2 123 !Q:0,1|4,4|16,17|21,24|41,42|48,50|65,66|87,89|107,122 Q:2,3|5,15|18,20|25,40|43,47|51,64|67,86|90,106 ??SS?HHHHHHHHHHS??SSS????HHHHHHHHHHHHHHTT??TTTSS???HHHHHHHHHHHHTT??STHHHHHHHHHHHHHHHHTT???SSSSTTHHHHHHHHHHH???????????????? 1HEK|A PF08724.5_Rep_N_seed 9 199 !Q:7,10|15,15|18,19|29,34|37,40|45,45|49,51|73,81|89,91|94,94|103,103|106,107|130,133|141,141|146,147|150,150|152,153|166,167|177,178|187,187 Q:0,6|11,14|16,17|20,28|35,36|41,44|46,48|52,72|82,88|92,93|95,102|104,105|108,129|134,140|142,145|148,149|151,151|154,165|168,176|179,186|188,198 EEEEEEE????TTTT?TT??HHHHHHHHH??????TT????GGGS?HHH---HHHHHHHHHHHHHHHHHHHTS-??-----?EEEEEEE?--SS?EEEEEEEE?TT??HHHHHHHHHHHHHHHHHHTSTT????STTSEEE?BSST--TS?B??EETTHHHHHTTT??TTTEEEEEE??GGGTTGGG?HHHHHHHHHHH 1M55|A PF08725.6_Integrin_b_cyt_seed 33 48 !Q:0,0|28,28|38,38|40,42|46,47 Q:1,27|29,37|39,39|43,45 ?HHHHHHHHHHTHHHHHHHHHHHHHHHH?SSSSSHHHH?S-??SSS?? 2BRQ|C PF08726.5_EFhand_Ca_insen_seed 23 82 !Q:0,1|15,15|19,20|24,24|33,33|38,38|46,46|48,57|60,65|68,69|71,71|81,81 Q:2,14|16,18|21,23|25,32|34,37|39,45|47,47|58,59|66,67|70,70|72,80 ??STHHHHHHHHHHH-TTS?-SSB?HHHHHHHS?HHHH-HHHHHHS?S??-------?SS----??TT?-B?HHHHHHHHT? 1MUX|A PF08727.6_P3A_seed 21 61 !Q:0,0|3,7|9,12|14,16|29,30|42,48|51,52|54,55|57,60 Q:1,2|8,8|13,13|17,28|31,41|49,50|53,53|56,56 ?SS?????S???-S???SSTTTHHHHHHH??HHHHHHHHHHT?????-?SS??S??S???? 1NG7|A PF08746.6_zf-RING-like_seed 12 59 !Q:0,0|4,5|7,7|13,13|16,17|19,20|22,33|35,35|46,46|49,52|54,56 Q:1,3|6,6|8,12|14,15|18,18|21,21|34,34|36,45|47,48|53,53|57,58 ?SSS??B?SSSEE?SS--S??E------------E?HHHHHHHSTT?SS?-??T---TT 2CT0|A PF08751.6_TrwC_seed 34 574 !Q:13,13|15,36|41,46|50,50|55,55|63,69|71,80|82,84|87,91|99,104|106,106|109,122|125,127|129,129|133,133|137,238|248,249|261,264|269,269|283,283|287,287|289,289|299,300|302,302|307,312|321,321|323,333|336,345|357,357|359,398|400,400|404,408|411,412|414,414|416,429|451,451|456,459|462,464|466,470|474,474|481,482|490,492|507,508|511,519|521,522|529,534|540,549|565,566|568,573 Q:0,12|14,14|37,40|47,49|51,54|56,62|70,70|81,81|85,86|92,98|105,105|107,108|123,124|128,128|130,132|134,136|239,247|250,260|265,268|270,282|284,286|288,288|290,298|301,301|303,306|313,320|322,322|334,335|346,356|358,358|399,399|401,403|409,410|413,413|415,415|430,450|452,455|460,461|465,465|471,473|475,480|483,489|493,506|509,510|520,520|523,528|535,539|550,564|567,567 EGGGTTHHHHTTS?S??--------------------GGGS------SSS?SEEE-ESHHHHH-------T----------T?-?SS?--?-HHHHHHH------H-HT???-----------SS???S?TTS?TTS??----------------------------------------------------------------------------------------------------EEEEEEEEE??HHHHHHHHTTT?---HHHH-HHHHHHHHHHHHH-HHT-T?EEEEEETTE--E-EEEE??-???EEEEEEEE?T-----------TS---------?EEEEEEEEEES?E----------------------------------------E?TTS----?EE??B?H--------------HHHHTHHHHHHHHHHHHHHHH-HHTT--??EE---E?----SSS?EEETTS?-HHHHHTT--?HHHHHHHHHHHHTT??TT---------S??HHHHHH------HHHHT????-???-?HHHHHHHHHHHHHHT--T?---?? 2A0I|A PF08752.5_COP-gamma_platf_seed 81 192 !Q:11,11|13,16|20,23|25,30|33,33|36,39|42,42|44,44|58,60|73,74|90,92|95,105|112,112|117,119|121,121|123,124|133,136|139,140|143,145|151,151|160,160|162,162|166,168|170,170|172,177|184,186|190,190 Q:0,10|12,12|17,19|24,24|31,32|34,35|40,41|43,43|45,57|61,72|75,89|93,94|106,111|113,116|120,120|122,122|125,132|137,138|141,142|146,150|152,159|161,161|163,165|169,169|171,171|178,183|187,189|191,191 HHHHHHHHHHT?G----GGT----T?-????EE?SS---?EE?S?TTSSEEEEEEEEE?--SSEEEEEEEEEE??TTEEEEEEEEEEEES---SS--------?--EEEEEE?EEEE?--B-T??EEEEEEEE??--SS?-TT???EEEEE-EEEEEEEE-B?TTT?-?B?S----??EEEEEE???EEE?G 1PZD|A PF08753.6_NikR_C_seed 39 84 !Q:29,33|42,42|74,77|82,83 Q:0,28|34,41|43,73|78,81 EEEEEEEEESSSSSHHHHHHHHHGGGTTT-----EEEEEEEE?SSSEEEEEEEEEEEHHHHHHHHHHHHSSTTB????EEEE?? 1Q5Y|A PF08755.6_YccV-like_seed 64 128 !Q:0,1|4,4|7,7|15,16|25,51|59,59|62,76|88,92|95,97|99,100|103,103|107,110|120,127 Q:2,3|5,6|8,14|17,24|52,58|60,61|77,87|93,94|98,98|101,102|104,106|111,119 ??SS?TT?EEEETTT??EEEEEEEE????????????????-?--??-????EEEEEEE?SS?-------------?EEEEEEEGGGE-----EE???S??TT?HHH----HHHHHHHTT?--????? 1VBV|A PF08758.6_Cadherin_pro_seed 52 115 !Q:0,3|5,6|8,8|13,16|18,18|20,20|23,24|26,33|36,38|40,42|45,47|52,54|71,72|74,74|78,78|93,104|113,114 Q:4,4|7,7|9,12|17,17|19,19|21,22|25,25|34,35|39,39|43,44|48,51|55,70|73,73|75,77|79,92|105,112 ????B??S?EEEE????S-S?SS??E--------EE???B??-SS???EEEE???SSEEEEETTTEEEEES??S?SSS?EEEEEEEEETTTTE------------EEEEEEEE?? 1OP4|A PF08761.6_dUTPase_2_seed 34 301 !Q:16,16|20,29|33,34|40,44|59,73|77,77|80,94|98,144|163,164|166,226|231,232|234,234|253,253|256,257|259,259|276,280 Q:0,15|17,19|30,32|35,39|45,58|74,76|78,79|95,97|145,162|165,165|227,230|233,233|235,252|254,255|258,258|260,275|281,300 HHHHHHHHHHHHHHHH?TTH----------HHH??HHHHH-----HHHHHHHHHHHTTS------------???SSS?TT-----------????HHH-----------------------------------------------HHHHHHHHHHHHHHHHHH??S??????????????????????????????????????????????????????????--?GGGT??S?TTSHHHHHHHHHHHHHHH-HT--T?HHHHHHHHHHHHHHHT??---HHHHHHHHHHHHHHHHHTTG 2CJE|A PF08762.5_CRPV_capsid_seed 7 255 !Q:1,2|6,6|12,14|23,23|33,33|37,37|42,42|45,46|48,49|51,51|53,63|66,67|69,76|90,91|110,111|113,113|120,120|130,131|135,139|145,147|154,155|161,161|173,176|180,180|183,185|190,195|202,202|206,206|208,208|217,218|232,232|234,234|237,237|243,247|249,249|252,254 Q:0,0|3,5|7,11|15,22|24,32|34,36|38,41|43,44|47,47|50,50|52,52|64,65|68,68|77,89|92,109|112,112|114,119|121,129|132,134|140,144|148,153|156,160|162,172|177,179|181,182|186,189|196,201|203,205|207,207|209,216|219,231|233,233|235,236|238,242|248,248|250,251 H--HHH-HHTSS???BHHHHTTS?EEEEEEEEE?STT?EEEE?TT??B??B?S-----------SS??S???-----HHHHHGGGEEEEE??EEEEEEEEEESSTTSEEE??S?EEEEEE?SSSHHHHHH??TTS?----SEEEE???TTTTTS??EEEEE?HHHHSSEEEEE????SSS?EE???BSSS???---HHHHHT-TSS?S?EEEEEESS??TTTBEEEEEEEEE-E?TT?EEEEE?????E-EE??? 3NAP|A PF08763.6_Ca_chan_IQ_seed 25 35 !Q:0,2|29,34 Q:3,28 ???TTTHHHHHHHHHHHHHHHHHHHHHHT?????? 2F3Y|B PF08764.5_Coagulase_seed 11 286 !Q:0,8|10,10|17,20|44,44|48,48|92,95|97,97|100,100|102,105|109,115|149,151|179,179|198,199|203,207|231,235|237,242|247,247|250,252|254,254|272,273|275,275|280,280|283,285 Q:9,9|11,16|21,43|45,47|49,91|96,96|98,99|101,101|106,108|116,148|152,178|180,197|200,202|208,230|236,236|243,246|248,249|253,253|255,271|274,274|276,279|281,282 ?????????S?STTTTS????HHHHHHHHHHHHHHHHHHHHHHH?GGG?STTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?---S?TT-S????TTT???????HHHHHHHHHHHHHHHHHHHHHHHHHHHTSGGGS???HHHHHHHHHHHHHHHHHHHHHHHHHHS?TTTHHHHHHHHHHHHHHH??SSS?????SHHHHHHHHHHHHHHHHHHHHHH?????S??????TTTS?TT---T?HHHHHHHHHHHHHHHHH??S?GGGT?SS??? 1NU9|C PF08765.6_Mor_seed 17 121 !Q:0,1|22,25|27,32|48,48|51,56|73,82|85,85|95,96|110,120 Q:2,21|26,26|33,47|49,50|57,72|83,84|86,94|97,109 ??HHHHHHHHHHHHHHHHHHTS----S?-----TTSHHHHHHHHHHHH?SS??????SHHHHHHHHHHHHHHH??--------SS?HHHHHHHHT??HHHHHHHHHHHHH?????????-? 1RR7|A PF08766.6_DEK_C_seed 59 60 !Q:0,0|16,17|21,22|24,24|35,35|39,41|43,44 Q:1,15|18,20|23,23|25,34|36,38|42,42|45,59 ?HHHHHHHHHHHHTTS-?GGG??H-HHHHHHHHHH?SSS??-S--HHHHHHHHHHHHHHH 1Q1V|A PF08767.6_CRM1_C_seed 29 413 !Q:27,27|33,36|61,100|104,104|124,124|126,126|130,131|148,151|175,175|197,197|204,205|207,207|224,224|247,259|287,289|311,317|319,319|324,329|334,334|351,351|355,355|372,392|410,412 Q:0,26|28,32|37,60|101,103|105,123|125,125|127,129|132,147|152,174|176,196|198,203|206,206|208,223|225,246|260,286|290,310|318,318|320,323|330,333|335,350|352,354|356,371|393,409 HHHHHHHHHHHHHHHHHHHHHHHHHHH?GGGGS----SHHHHHHHHHHHHHHHHHHHHHHT??-------------------------------------?HHH-HHHHSSHHHHHHTHHHHHH-S?GGG??HHHHHHHHHHHHHHGG----GTTTTHHHHHHHHHHHHHTTSSS?SSSSHHHHHHHHHHHHHHHHH?TTHHHH--S?HHHHHHHHHHHHHHTT?SSHHHHHHHHHHHHHHHHHHHH------------?HHHHHHHHHHHHHHHHHHHHHHHTSTT--?GGGHHHHHHHHHHHHHHHTTT-----??S?SSSS------STTS?HHHHHHHHHHHHHHHH?TTS?HHHHHHHHHHHHHSTT-?-------------------HHHHHHHHHHHHHHHSS??? 4HAV|C PF08768.6_DUF1794_seed 55 289 !Q:9,9|16,17|21,22|26,32|35,37|46,46|48,52|55,59|66,67|70,85|90,93|96,101|113,115|121,155|175,178|189,189|196,196|201,201|205,209|212,238|247,249|261,261|263,267|272,274|276,276|288,288 Q:0,8|10,15|18,20|23,25|33,34|38,45|47,47|53,54|60,65|68,69|86,89|94,95|102,112|116,120|156,174|179,188|190,195|197,200|202,204|210,211|239,246|250,260|262,262|268,271|275,275|277,287 GGGGGGGGG?EEEEEE--EEE??TTS----?-?EE---EEEEEEEE-E?----SS-----SEEEEE--EE----------------EEET----TT??----EEEEEEEEEEE---SSTTE-----------------------------------EEEEEEETTTEEEEEEEEE----EEETTEEEEE-EETTTT?EEEE?TTS-?--?EE---------------------------EEEEEEEE---ETTEEEEEEEE-E-----ETTE---E-EEEEEEEEEEE? 3EMM|A PF08769.6_Spo0A_C_seed 28 152 !Q:10,11|30,30|52,52|72,72|81,81|85,109|112,112|115,138 Q:0,9|12,29|31,51|53,71|73,80|82,84|110,111|113,114|139,151 HHHHHHHHHT??TTSHHHHHHHHHHHHHHH?GGGGGGTTTTHHHHHHHHHTS?HHHHHHHHHHHHHHHHHSS?TTTTHHHH?HHH-------------------------HT?SS???---------------------HHHHHHHHHHHHH 1FC3|A PF08770.6_SoxZ_seed 88 106 !Q:0,0|4,5|7,9|11,12|23,27|29,29|31,32|34,34|36,36|38,39|41,43|45,45|64,64|68,68|71,71|80,80|84,85|97,97 Q:1,3|6,6|10,10|13,22|28,28|30,30|33,33|35,35|37,37|40,40|44,44|46,63|65,67|69,70|72,79|81,83|86,96|98,105 ?EEE??S---B??TTEEEEEEEE?????B?S??B?S-S??B???B?EEEEEEEETTEEEEEEEE?TTB?SS?EEEEEEEE?SSE--EEEEEEEETTS?EEEEEEEE 2OXH|A PF08771.6_Rapamycin_bind_seed 38 107 !Q:7,7|19,19|26,29|32,33|51,54|83,85 Q:0,6|8,18|20,25|30,31|34,50|55,82|86,106 HHHHHHS?HHHHHHHHHHH-HHHHHH----TT??HHHHHHHHHHHHHHHHT-???SHHHHHHHHHHHHHHHHHHHHHHHHHHH??-SSHHHHHHHHHHHHHHHHHHH 4JSP|A PF08772.6_NOB1_Zn_bind_seed 37 81 !Q:0,6|11,11|15,16|20,24|27,28|30,30|34,35|37,39|44,44|46,49|52,54|56,80 Q:7,10|12,14|17,19|25,26|29,29|31,33|36,36|40,43|45,45|50,51|55,55 ???????EEEE?SSS??EES----?SS??S?SSS??S-??EEEE?B??--SS???B??????????????????-----?? 2CON|A PF08773.6_CathepsinC_exc_seed 10 121 !Q:0,1|3,6|19,21|23,26|30,32|35,39|54,54|58,58|100,100|110,110|120,120 Q:2,2|7,18|22,22|27,29|33,34|40,53|55,57|59,99|101,109|111,119 ??S????HHHHSEEEEEEE???B---?STT???SS?????EEEEEEEETTTEEE?SSS?EEEEEEETTTEEEEEETTEEEEEEEEEEEETTEEEEEEEEE?SEEEEETTS?SEEEEEEEE? 3PDF|A PF08775.5_ParB_seed 15 133 !Q:0,0|2,2|6,7|23,26|48,49|71,79|85,86|91,91|97,99|103,104|111,112|120,122 Q:1,1|3,5|8,22|27,47|50,70|80,84|87,90|92,96|100,102|105,110|113,119|123,132 ?S?GGG??HHHHHHHHHHHHTTT????HHHHHHHHHHHHHHTTTSSSS??TTTSHHHHHHHHTGGGHHHHT???????-?EEESS??SSSS?EEEEE?--SSS??EEEEES??HHHHHHH---HHHHHHHHHH 2NTZ|A PF08776.6_VASP_tetra_seed 6 43 !Q:0,0|30,32|40,42 Q:1,29|33,39 ?HHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHHH??? 1USD|A PF08777.6_RRM_3_seed 15 115 !Q:0,1|9,10|13,15|24,24|27,31|37,38|41,41|51,55|67,67|71,71|73,73|84,85|105,111|113,114 Q:2,8|11,12|16,23|25,26|32,36|39,40|42,50|56,66|68,70|72,72|74,83|86,104|112,112 ??EEEEEES??SS??-HHHHHHHT?SS?---?EEEEE??TT?SEEEEEESS?----HHHHHHHHHHT-TTS?B?TTSSSEEEEE??HHHHHHHHHHHHHHHHHHH--?????S?? 1OWX|A PF08778.5_HIF-1a_CTAD_seed 15 43 !Q:0,3|6,12|21,23|26,27|29,29|40,42 Q:4,5|13,20|24,25|28,28|30,39 ????SS?---???HHHHHHHS???SS??S?SSHHHHHHHT??? 1L3E|A PF08779.5_SARS_X4_seed 2 86 !Q:1,2|17,17|22,22|29,32|43,44|52,52|56,56|60,60|67,67|71,74|80,80|84,85 Q:0,0|3,16|18,21|23,28|33,42|45,51|53,55|57,59|61,66|68,70|75,79|81,83 B??EEEEEETTSEEEEE?SSSS?EEESSS???-EETTTEEEEE??SEEEEEE?TTS?EEE-EEEEEE?SSS????SSSSS?SSS?? 1XAK|A PF08780.6_NTase_sub_bind_seed 40 143 !Q:0,1|21,21|29,29|62,62|65,65|67,69|71,71|74,75|89,92|94,94|98,98|127,127|142,142 Q:2,20|22,28|30,61|63,64|66,66|70,70|72,73|76,88|93,93|95,97|99,126|128,141 ??HHHHHHHHHHHHHHHHHHH?HHHHTTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HT?S???T-TS??HHHHHHHHHHTTS?---S?HHH-HHHHHHHHTTGGGTTSHHHHHHHHHTHH-HHHHHHHHHHHHHH? 1JOG|A PF08781.5_DP_seed 24 168 !Q:12,12|51,53|62,62|71,72|78,78|91,92|95,95|116,118|130,150|166,166 Q:0,11|13,50|54,61|63,70|73,77|79,90|93,94|96,115|119,129|151,165|167,167 HHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSS???GGGEEESS?EEEEEESS??EEEEE?TTSSEEEEEESS?-EE-EEEHHHHHHHTTTTTTGGGT???HHHHHHHHHTS?--------------------GGGHHHHHHHHHTTT?S 2AZE|A PF08782.5_c-SKI_SMAD_bind_seed 7 97 !Q:0,1|6,6|10,10|16,16|20,21|25,27|34,35|38,38|45,47|49,52|60,61|69,69|72,72|75,77|95,97 Q:2,5|7,9|11,15|17,19|22,24|28,33|36,37|39,44|48,48|53,59|62,68|70,71|73,74|78,94 ??EEEE?STT?EEEEE?GGG??STT???EEETTT??EE?HHHHTT???S???-SSEEEES??GGGHHHH?EE?TT???TTHHHHHHHHHHHHHHH??- 1MR1|C PF08783.6_DWNN_seed 26 90 !Q:6,6|8,8|11,11|21,21|38,40|44,49|60,66|68,68|70,71|75,75|81,82 Q:0,5|7,7|9,10|12,20|22,37|41,43|50,59|67,67|69,69|72,74|76,80|83,89 EEEEET-T?SS-EEEEEESSS-EEEHHHHHHHHHHHHT?-?TTT------EEEEEEESSS??-----E-E?-STT?EEETT??EEEEEEE 2C7H|A PF08784.6_RPA_C_seed 23 129 !Q:8,128 Q:0,7 HHHHHHHT??????-----------????????????---------????????????------?-??????????????---?????????????-???-???????????????????????????? 1Z1D|A PF08785.6_Ku_PK_bind_seed 9 135 !Q:3,3|18,20|40,41|64,64|83,84|90,90|95,102|105,105|108,108|116,116|118,119|128,131|134,134 Q:0,2|4,17|21,39|42,63|65,82|85,89|91,94|103,104|106,107|109,115|117,117|120,127|132,133 SSS?TTHHHHHHHHSSSS?--HHHHHHHHHHHHHHHHHSS-?SHHHHHHHHHHHHHHHHHHHHT?SHHHHHHHHHHHHHHHHS??HHHHH-HHHH--------HT?SS?SSSSSSS?S??THHHHHHT?---SS? 1Q2Z|A PF08786.6_DUF1795_seed 39 163 !Q:9,9|13,14|21,22|27,28|37,39|43,43|56,56|63,63|68,73|83,86|93,101|106,106|120,121|123,131|142,144|162,162 Q:0,8|10,12|15,20|23,26|29,36|40,42|44,55|57,62|64,67|74,82|87,92|102,105|107,119|122,122|132,141|145,161 SEEEEEETT-SEE??BEEEEE??BTTB??EEEEEEEE???TTS?HHHHHHHHHHHH-HHHSTT?EEEE------EEEEEETTE----EEEEEE---------EEEE-ETTEEEEEEEEEE??S---------SSEEEEEEEE--?GGGHHHHHHHHHHHHHT? 3LYD|A PF08787.6_Alginate_lyase2_seed 70 439 !Q:0,0|3,4|12,12|14,26|29,37|41,42|45,50|53,60|82,86|88,93|96,96|99,99|108,129|131,131|135,135|137,148|159,160|162,164|166,166|185,195|198,200|203,203|209,210|213,214|218,228|236,244|248,248|250,251|254,255|264,265|268,270|276,280|283,283|288,298|305,307|312,316|324,324|326,329|332,333|343,343|345,345|352,352|355,355|364,368|370,370|377,380|390,398|402,402|406,411|415,415|424,424|436,436|438,438 Q:1,2|5,11|13,13|27,28|38,40|43,44|51,52|61,81|87,87|94,95|97,98|100,107|130,130|132,134|136,136|149,158|161,161|165,165|167,184|196,197|201,202|204,208|211,212|215,217|229,235|245,247|249,249|252,253|256,263|266,267|271,275|281,282|284,287|299,304|308,311|317,323|325,325|330,331|334,342|344,344|346,351|353,354|356,363|369,369|371,376|381,389|399,401|403,405|412,414|416,423|425,435|437,437 ?TT--GGGEEEE?T-------------TS--------?EES??TT----??BT--------TTEEEEEETTEEEEEEEEESS-----S?---??TT?SS?EEEEEESS---------------------?B?TTT?E------------EEEEEEEEEE??S?--S?TTSTTTTEEEEEEEEESS-----------TT???SE-EEEEE??TT-?SEE-----------EEEEEEE??-------BSS?G--GG??EEEEEEES??TT???SBTTB?????TT?EETT---------??EEEEEE---EETT-----EEEEEEE?T----TS??EEEEEESSS?S?SSGGGS?HH-HHHHTTTT?????B?TTTTTT??--EEEEEEEEE?---?????GGG?TTT??????GGG?HHHHHHTT?EEEEEEEEEEE-E? 2CWS|A PF08788.6_NHR2_seed 5 70 !Q:0,6|8,9|20,21|44,44|66,69 Q:7,7|10,19|22,43|45,65 ???????S??HHHHHHHHHH--HHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHHH???? 1WQ6|A PF08790.6_zf-LYAR_seed 30 29 !Q:10,10|18,22|24,24 Q:0,9|11,17|23,23|25,28 EEETTTTEEE-EGGGTTT?????S?TTSS 1WJV|A PF08794.5_Lipoprot_C_seed 2 155 !Q:0,0|13,23|36,36|38,38|44,44|47,47|82,83|89,90|100,100|103,103|130,131 Q:1,12|24,35|37,37|39,43|45,46|48,81|84,88|91,99|101,102|104,129|132,154 ?SSEEEEEEEEEE???????????EEEEEEEEEEEE?B?BGGGS?SS?EEEEEEEEEETTEEEEEEEEEEETTTTEEEEEEE??SSGGG??EEEEEEEEE?TT?BEEEEEEEEETTEEEEEEEEEEESTT??EEEEEEEEEETTEEEEEEEEEEE 2YPV|A PF08796.5_DUF1797_seed 17 75 !Q:17,17|40,42|62,62 Q:0,16|18,39|43,61|63,74 HHHHHHHHHHHHHHHTS?EEEEEEETTEEEEEEEEETTTT---EEEEEEEETTEEEEEEEES?HHHHHHHHHHHH 2FFG|A PF08797.6_HIRAN_seed 51 227 !Q:0,1|3,6|8,16|20,34|38,47|49,52|55,55|58,61|64,64|66,109|115,134|137,139|142,147|150,161|177,177|182,186|193,202|207,210|213,217|224,224 Q:2,2|7,7|17,19|35,37|48,48|53,54|56,57|62,63|65,65|110,114|135,136|140,141|148,149|162,176|178,181|187,192|203,206|211,212|218,223|225,226 ??B????B-------??STT---------------TTS-------???S----SS?EE????TT?T--------------------------------------------THHHH--------------------HH???TT------BG------------GGGGHHHHHHHHHHH-HTTS?---?EEEEEE??--------TTTT----TT?????EEEEEE?HH 2L1I|A PF08798.6_CRISPR_assoc_seed 50 310 !Q:0,0|8,8|18,27|30,30|45,50|56,59|64,76|80,81|90,92|97,97|100,111|116,118|121,126|129,129|138,139|142,183|187,187|195,196|207,207|209,229|245,268|282,282|293,293|297,297|302,305|309,309 Q:1,7|9,17|28,29|31,44|51,55|60,63|77,79|82,89|93,96|98,99|112,115|119,120|127,128|130,137|140,141|184,186|188,194|197,206|208,208|230,244|269,281|283,292|294,296|298,301|306,308 ?EEEEEEE?TTSHHHHHH----------HH?HHHHHHHHHGGGHH------HHHTT????EEEE?---------???TTS??EEEEEESS???GGGS?TT------------SEEE???EE??????TT?EEEEEEEE??SS??---------------------------?????---?????HHH-HHHHHHH--HHHHHTTEEE?E---------------------ETTEESEEEEEEEEE?????????--------???????EEEEEEEEEEEES?HHHHHHHHHH?SSS?TTTT????EEE? 1WJ9|A PF08799.6_PRP4_seed 61 30 !Q:9,10|16,17|29,29 Q:0,8|11,15|18,28 HHHHHHHTT??SEETT??HHHHHHHHHHH? 2DK4|A PF08801.6_Nucleoporin_N_seed 57 837 !Q:3,4|13,15|24,52|55,55|80,80|82,115|120,120|124,147|149,153|155,155|160,169|172,172|174,176|178,179|181,182|200,205|214,214|218,233|245,245|249,249|253,253|273,274|278,299|305,363|365,365|376,380|391,391|398,403|411,417|422,422|434,464|466,469|477,478|485,486|489,509|511,511|523,524|527,533|537,563|570,572|579,617|625,626|628,633|635,635|638,638|641,647|661,697|706,706|709,726|730,731|735,736|738,746|752,752|754,755|757,757|760,778|784,789|791,794|796,796|803,806|808,808|817,823|825,825 Q:0,2|5,12|16,23|53,54|56,79|81,81|116,119|121,123|148,148|154,154|156,159|170,171|173,173|177,177|180,180|183,199|206,213|215,217|234,244|246,248|250,252|254,272|275,277|300,304|364,364|366,375|381,390|392,397|404,410|418,421|423,433|465,465|470,476|479,484|487,488|510,510|512,522|525,526|534,536|564,569|573,578|618,624|627,627|634,634|636,637|639,640|648,660|698,705|707,708|727,729|732,734|737,737|747,751|753,753|756,756|758,759|779,783|790,790|795,795|797,802|807,807|809,816|824,824|826,836 GGG??EEEEEEEE-??HHHHTTTS??---------------------------SS?EEEEEETTTTEEEEEETTEEEEEE-T----------------------------------TTSS?EEE------------------------E-????S?EEEE----------EE-E???T--T--STTTTSSEEEEEEESSE------EEEEEEEE?SSS?--------------?EEEEEEEEEEE?TTT?EEE-EEEETTTTEEEEEETTSTT??EEE--??-???????---???????EEESS??-???----?????????????---------------------???????????????S-EEEEEEETTT-----TEEEEEETTS?EEEEEE------ETTEEEE-------EEEE?HHHHHHHHHHH-------------------------------T????GGGSTTT??EEEEEE??TT---------------------T?SSEEEEEEETT??EE-------EEE??-------------------------EETTEE???EEEEEE?????????----------????????????????????THHHHTT??T------T?SB?TT?------EEETTTEEEEEEE????????????--------------???????????EEEEEEEE?HH------------------HHH--HHS??E---------EEEEE?S??S?EE-------------------EEEES------S????S?SSSTTT----T?HHHHTTTS----???E-EEEEESSEEEE 1XKS|A PF08802.5_CytB6-F_Fe-S_seed 19 39 !Q:0,4|36,38 Q:5,35 ?-???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS??? 2ZT9|D PF08803.6_ydhR_seed 23 100 !Q:11,12|29,32|35,38|40,40|55,55|67,67|75,75|79,80|82,83|85,86|88,88 Q:0,10|13,28|33,34|39,39|41,54|56,66|68,74|76,78|81,81|84,84|87,87|89,99 EEEEEEESSSS-?SHHHHTTHHHHHHHHT????BS????B?BTTTTEEEEEEEES?HHHHHHHHHHH-HHHHHHH-SSS??B??B??B?GGGGGGTTTTT 2ASY|A PF08804.5_gp32_seed 10 102 !Q:4,9|13,13|21,23|29,30|46,46|52,52|58,59|62,62|74,74|76,80|83,83|90,93|96,96 Q:0,3|10,12|14,20|24,28|31,45|47,51|53,57|60,61|63,73|75,75|81,82|84,89|94,95|97,101 GGTB??????TTS?EEEEEEE???SSSSS-?SSEEEEEEEEEETTE-EEEEE?GGGGT??TT?HHHHHHHHTTH-H-----HH?HHHHHH----HS?EEEEE 1GPC|A PF08805.6_PilS_seed 18 170 !Q:0,3|24,26|28,32|47,47|53,54|67,67|71,71|80,82|86,88|98,98|113,116|125,130|135,140|146,149|153,155|160,161|169,169 Q:4,23|27,27|33,46|48,52|55,66|68,70|72,79|83,85|89,97|99,112|117,124|131,134|141,145|150,152|156,159|162,168 ????HHHHHHHHHHHHHHHHHHTT?-?S?????HHHHHHHHHHTTTT-TTSEE--EEEGGGTEEEEE?TTS?EEEEEEES???SSS??-EEEEEEEEE?HHHHHHHHHHHHHH?-??SEEEETTE------EETT?--???HHHHH----HHS???BTTB??EEEEEEE? 3FHV|A PF08806.6_Sep15_SelM_seed 12 81 !Q:9,11|26,28|42,44|50,50|54,56|59,59|62,62|66,66|79,80 Q:0,8|12,25|29,41|45,49|51,53|57,58|60,61|63,65|67,78 EEEEEEETT???STTHHHHHHTTTHH---HHBTTEEEEEESS???EEEEE?SSS???EE-EE?SSS?HHHHHHHHHHHT?? 2A2P|A PF08807.5_DUF1798_seed 19 114 !Q:19,20|24,28|59,60|63,64|85,86|88,88 Q:0,18|21,23|29,58|61,62|65,84|87,87|89,113 HHHHHHHHHHHHHHHHHHH--HHS?????TTTTHHHHHHHHHHHHHHHHHHHHHHHHHS??SS??HHHHHHHHHHHHHHHHHHHH??S?HHHHHHHHHHHHHHHHHHHHHHHHH 2IM8|A PF08810.5_KapB_seed 10 120 !Q:17,18|29,54|57,57|69,70|72,76|95,96|99,101|119,119 Q:0,16|19,28|55,56|58,68|71,71|77,94|97,98|102,118 ETTEEEEEEEEEEETTE--EEEEEEEEEE?????????????-????????????TT?EEEEEGGGEEE??S-????HHHHHHHHHHHHHHTTTT??SH---HHHHHHHHHHHHHHHTT? 1Y71|A PF08814.5_XisH_seed 8 137 !Q:0,3|19,19|26,28|33,33|36,45|60,63|67,67|90,90|122,123 Q:4,18|20,25|29,32|34,35|46,59|64,66|68,89|91,121|124,136 ????HHHHHHHHHHHHHTT?EEEESS???EETT-EE??????????EEEEETTEEEEEEE????TTS?HHHHHHHHHHHHHHHHHHHHHH?TTEEEEEEEEHHHHHTGGGSHHHHHHHHHTT??EEEEETTTTEEEE 2OKF|A PF08815.5_Nuc_rec_co-act_seed 10 51 !Q:0,2|20,21|45,50 Q:3,19|22,44 ???SHHHHHHHHHHHHTTSS??TTHHHHHHHTTHHHHHHHTGGGS?----- 2C52|B PF08816.6_Ivy_seed 17 133 !Q:17,18|20,21|28,28|30,30|32,35|52,52|55,56|72,75|83,84|86,86|93,93|98,98|105,107|110,117|128,128 Q:0,16|19,19|22,27|29,29|31,31|36,51|53,54|57,71|76,82|85,85|87,92|94,97|99,104|108,109|118,127|129,132 HTTSHHHHHHHHHHTSS??S??HHHHTT?S?B?-??EEEEETTEEEEEEEEE?TT?-TTTEEEEEEEETTSS?---EEEEEEE??S?TTTTTT?GGGT?EEEEES???HH--------HHHHHHHHHH-TSTT 1XS0|A PF08817.5_YukD_seed 54 119 !Q:0,0|8,16|19,19|22,24|48,60|62,75|78,78|80,82|87,90|95,96|109,110|113,113|118,118 Q:1,7|17,18|20,21|25,47|61,61|76,77|79,79|83,86|91,94|97,108|111,112|114,117 ?EEEEEEE?--------TT-TT??-EEEEEEETTSBTTHHHHHHHHHS?----------??S??-----------?TT?E---EEEG----GGTE--EEETTSBTGGGT??TT?EEEE? 2BPS|A PF08818.6_DUF1801_seed 150 156 !Q:13,13|17,17|20,25|32,38|46,47|50,66|73,75|78,79|86,89|94,94|97,105|107,107|113,115|120,120|123,123|126,126|133,133|135,142 Q:0,12|14,16|18,19|26,31|39,45|48,49|67,72|76,77|80,85|90,93|95,96|106,106|108,112|116,119|121,122|124,125|127,132|134,134|143,155 GGHHHHHHHHHHH-HHH?TT----?-EEEEET-------TEEEEES--TT?---------------?SEEEEE--?SS--EEEEES----SSHH-HH---------T-THHHH---HHHT?EE?SS?EEEETT-S-???----HHHHHHHHHHHHH 2OC6|A PF08824.5_Serine_rich_seed 12 172 !Q:0,1|27,27|29,33|35,35|38,38|42,42|78,78|81,81|113,113|115,115|122,124|127,132|135,135|166,171 Q:2,26|28,28|34,34|36,37|39,41|43,77|79,80|82,112|114,114|116,121|125,126|133,134|136,165 ??HHHHHHHHHHHHHHHHHHHHHHHHH?S-----S?TT?HHH-HHTTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?SS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-T?HHHHTT?-?SS?-----TT?HHHHHHHHHTTHHHHHHHHHHHHHHTHHHH?????? 2L81|A PF08825.5_E2_bind_seed 24 102 !Q:3,3|18,18|22,23|26,26|32,32|46,47|67,68|71,71|76,84|86,86|89,89|91,91|93,93|101,101 Q:0,2|4,17|19,21|24,25|27,31|33,45|48,66|69,70|72,75|85,85|87,88|90,90|92,92|94,100 EEE?TTSBHHHHHHHHHH?TTT??SS?EEEEE-ETTEEEEEEETTS--HHHHHHHGGGGGSBTTTTT??TT?EEEE---------E?TT?S-S?EEEEEEE? 2LQ7|A PF08826.5_DMPK_coil_seed 6 62 !Q:57,57|60,61 Q:0,56|58,59 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HH?? 3CVE|A PF08827.6_DUF1805_seed 18 71 !Q:1,1|4,5|12,17|20,21|25,32|34,35|45,45|49,49|57,58|61,61 Q:0,0|2,3|6,11|18,19|22,24|33,33|36,44|46,48|50,56|59,60|62,70 E?TT??HHHHHH------TT??EEE??------S??SHHHHHHSB?SEE?HHHHHTT??TT?BHHHHGGGG 1QW2|A PF08828.5_DSX_dimer_seed 11 62 !Q:0,2|18,19|36,36|60,61 Q:3,17|20,35|37,59 ???HHHHHHHHHHHHHTT??GGGHHHHHHHHHHTTT?HHHHHHHHHHHHHHHHHHHHTTT?? 1ZV1|A PF08829.5_AlphaC_N_seed 5 196 !Q:0,18|21,21|26,26|29,29|49,51|59,59|61,61|63,63|82,83|85,85|96,96|102,102|104,104|110,110|120,121|141,141|163,165|183,184|186,187|196,196 Q:19,20|22,25|27,28|30,48|52,58|60,60|62,62|64,81|84,84|86,95|97,101|103,103|105,109|111,119|122,140|142,162|166,182|185,185|188,195 ?????-?????????????TT?SEEE?TT?TTTEETTEEEEEHHHHHTT???GGGGEEE?T-T?EEEEEEEETTEEESSGGG??S?EEEEEEEEEE?TTSSB?B?TTSSB?EEEEEEEEE??HHHHHHHHHHHHHHTSTTB?HHHHHHHHHHHHHHHHHHHHS???HHHHHHHHHHHHHHHTT??B--HHHHHHHS- 2O0I|1 PF08830.5_DUF1806_seed 14 119 !Q:2,3|18,18|28,40|52,52|60,60|64,64|73,74|85,85|90,90|93,94|116,118 Q:0,1|4,17|19,27|41,51|53,59|61,63|65,72|75,84|86,89|91,92|95,115 EE??HHHHHHHHHHTTTS?EEEEEEEEE???????????-?EEEEEEEEEEE?EEEEEEE-SSS-SEEEEEEE--SSSEEEEEEE?EEEE?TT??EEEEEEETTTTEEEEEEEESS??? 1NJH|A PF08831.5_MHCassoc_trimer_seed 10 73 !Q:2,2|14,14|17,23|25,25|38,38|60,61|64,70|72,72 Q:0,1|3,13|15,16|24,24|26,37|39,59|62,63|71,71 SS?HHHHHHHHHHH?TT???????S?HHHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHHT??SS?-?????S? 1IIE|A PF08832.5_SRC-1_seed 10 105 !Q:0,6|15,80|93,104 Q:7,14|81,92 ????-??HHHHHHHH??????-------????????????????????-?????????????????-----------????TTHHHHHHHHSS-??????????? 1XV9|E PF08833.5_Axin_b-cat_bind_seed 9 54 !Q:0,2|15,53 Q:3,14 ???TTHHHHHHHHHH?------??????????--------?????--??????? 1QZ7|B PF08837.6_DUF1810_seed 44 147 !Q:0,1|3,4|6,6|17,18|31,33|36,36|42,43|48,49|59,59|87,88|90,91|97,97|115,115|117,122|136,138|147,147 Q:2,2|5,5|7,16|19,30|34,35|37,41|44,47|50,58|60,86|89,89|92,96|98,114|116,116|123,135|139,146 ??T--T?THHHHHHHTT--THHHHHHHHHTT???SS?HHHHS??BTTS??SHHHHHTSB?SHHHHHHHHHSTTHHHHHHHHHHHHHH??S??HHHHS?TTHHHHHHHHHHHHHHH?S----??HHHHHHHHHHSTT???HHHHHHHH- 2JEK|A PF08838.5_DUF1811_seed 15 106 !Q:0,2|6,7|30,30|50,50|54,55|58,58|87,90|92,92|94,95|104,105 Q:3,5|8,29|31,49|51,53|56,57|59,86|91,91|93,93|96,103 ???GGG??HHHHHHHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHHHTTS?GGG??TT?EEEETTEEEEEEEEEEEETTEEEEEETT----S?S??EEEEGGGB?? 1SF9|A PF08839.6_CDT1_seed 11 221 !Q:0,1|26,28|33,33|45,47|58,58|66,72|74,90|96,144|147,148|151,153|183,183|188,191|195,198|200,201|204,205|209,209|211,220 Q:2,25|29,32|34,44|48,57|59,65|73,73|91,95|145,146|149,150|154,182|184,187|192,194|199,199|202,203|206,208|210,210 ??HHHHHHHHHHHHHHHHHHHHHHTT???BHHH-HHHHHHHHHSS???HHHHHHHHHH?GGGEEEE-------E?????????????????EEEEE???--------------------------------------------??TT??SS???HHHHHHHHHHHHHHHHHHHHHHHHHHHTT-TTTS????GGG??--S??TT??STT-S?????????? 2WVR|C PF08840.6_BAAT_C_seed 24 242 !Q:19,20|42,42|44,46|55,56|59,60|70,82|85,88|90,90|94,94|97,107|111,111|114,114|117,117|119,120|131,132|136,139|150,151|154,154|171,175|184,184|186,188|192,196|198,210|213,214|216,216|239,241 Q:0,18|21,41|43,43|47,54|57,58|61,69|83,84|89,89|91,93|95,96|108,110|112,113|115,116|118,118|121,130|133,135|140,149|152,153|155,170|176,183|185,185|189,191|197,197|211,212|215,215|217,238 EEHHHHHHHHHHHHTSTTB??SSEEEEEETHHHHHHHHHHHH?S--?EEEEEEES??SB??SSEEEETTE-------------EE????B?GGG?EE----------?SSS?EE?TT?B??TTSGGGGGGB??GGG?--?SEEEEEEETT??SS?HHHHHHHHHHHHHHTT??-??EEEEETTB?S???STT?????B?????????----BB??B?HHHHHHHHHHHHHHHHHHHHHH??? 1TQH|A PF08841.5_DDR_seed 12 338 !Q:6,6|19,20|26,26|37,37|50,50|54,57|70,70|73,73|76,77|86,86|93,96|110,110|116,116|118,118|133,134|143,143|153,153|157,157|165,165|180,180|182,182|193,193|198,198|205,205|209,209|213,213|216,218|229,229|231,231|233,233|237,238|241,243|271,273|277,277|281,282|309,309|311,312|314,315|321,321|323,324 Q:0,5|7,18|21,25|27,36|38,49|51,53|58,69|71,72|74,75|78,85|87,92|97,109|111,115|117,117|119,132|135,142|144,152|154,156|158,164|166,179|181,181|183,192|194,197|199,204|206,208|210,212|214,215|219,228|230,230|232,232|234,236|239,240|244,270|274,276|278,280|283,308|310,310|313,313|316,320|322,322|325,337 EEEGGG?HHHHHHHHHHSS??SEEEE?TTSHHHHHHH-HHHHHHHHHHTS?GGG????EEEEEEEEEEEE?BS?SS??EEEEEEEE-EEEEEE????THHHHHHHHHHHH?SEEEE?S?HHHHHHHHHTTSTT??SSEEEEEE?SSEEEEEEE?SSS?EEEEEEE?SHHHHHHHHHHHTT?S?HHHHHHHHHS?EEEB?SSSEEE?TTS?EEE?SS???TTTTTSEEEE?S-S?EEE?-SS???HHHHHHHHHHHHHHHHHHHHHHHHHHT?--TTS?TTS??EEEEESGGGGSSSHHHHHHHHHTTSS?B??B??GGGTS?S??HHHHHHHHHHHHT 2D0P|A PF08842.5_Mfa2_seed 87 559 !Q:0,21|28,38|40,53|56,56|58,59|64,65|73,78|80,80|84,84|98,101|104,123|125,136|139,141|144,144|146,148|156,163|165,173|179,195|199,199|202,204|207,207|212,225|228,228|231,231|233,243|245,248|253,254|259,268|270,270|274,274|284,285|291,300|305,313|319,321|327,332|338,340|343,345|350,350|352,357|359,361|365,366|368,377|381,382|388,406|411,411|415,417|420,426|429,432|440,441|444,448|453,453|462,467|472,474|482,483|486,488|495,517|520,540|542,542|550,550|556,557 Q:22,27|39,39|54,55|57,57|60,63|66,72|79,79|81,83|85,97|102,103|124,124|137,138|142,143|145,145|149,155|164,164|174,178|196,198|200,201|205,206|208,211|226,227|229,230|232,232|244,244|249,252|255,258|269,269|271,273|275,283|286,290|301,304|314,318|322,326|333,337|341,342|346,349|351,351|358,358|362,364|367,367|378,380|383,387|407,410|412,414|418,419|427,428|433,439|442,443|449,452|454,461|468,471|475,481|484,485|489,494|518,519|541,541|543,549|551,555|558,558 ??-???----------------EEEEEE--------???S--------------TT?S??HHHH??EEEEEEE?-----T-TSB-EEEEEEEESGGGG----SS?-----------------??E------------EE???SE-E---EEEEEEE--------S?-------?TTEEE???-------------?TTT?BG---GG?EEEE??-----------?TT?EE?S------?????E----EEEE--EEEE----------E?SSS?EEEEEEEEE??EEEEE----------EEEE---------SSSSS???GGGEE------EEEEE???EE---ETTS?B-----?S???EEE??S----------EEE-?SSTTT------------------?EEEE-EES???TT?----??EE----EEEETTT??EE-----EEEE-HHHHHHTS?-----GGGS???HHHHHHH??EE---EEEEEE----------------------?TT---------------------S?EEEEEET-TEEEE??G 3GF8|A PF08848.6_DUF1818_seed 27 122 !Q:14,14|17,18|23,23|26,26|31,31|53,55|58,58|61,61|68,68|89,89|92,98|100,101|106,106|120,121 Q:0,13|15,16|19,22|24,25|27,30|32,52|56,57|59,60|62,67|69,88|90,91|99,99|102,105|107,119 EEEETTEEEEEETT?SS??EEEE?SS?EEEE?HHHHHHHHHHHHHHHHHHHTS???SS?SS?EEEEEE?SSEEEEEEEETTEEEEEEEE?SS-------S??EEEE?TTTHHHHHHHHTT?? 2NVN|A PF08849.6_DUF1819_seed 25 201 !Q:0,5|11,14|28,30|42,42|45,52|60,60|68,68|73,77|83,83|85,85|101,101|121,121|123,124|139,139|142,147|166,175|177,183|193,193|196,196 Q:6,10|15,27|31,41|43,44|53,59|61,67|69,72|78,82|84,84|86,100|102,120|122,122|125,138|140,141|148,165|176,176|184,192|194,195|197,200 ??????SGGGG????HHHHHHHHHHHHH???HHHHHHHHHTS?TT????????HHHHHHH-HHHHTTS?HHHH-----HHHHH-S?HHHHHHHHHHHHHHH?HHHHHHHHHTHHHHTTSSS?B??HHHHHHHHHHHHHH?TT??????HHHHHHHHHHHHHHHHHT????--????B???????HHHHHHHHH-TT?HHHH 3BHW|A PF08853.6_DUF1823_seed 21 119 !Q:0,2|13,13|15,15|29,30|38,40|42,43|47,47|50,50|55,55|58,60|64,65|76,76|88,93|97,98 Q:3,12|14,14|16,28|31,37|41,41|44,46|48,49|51,54|56,57|61,63|66,75|77,87|94,96|99,118 ???HHHHHHHHHT?S?HHHHHHHHHHHHT??EETTTTE---E??TTS?HH-HHTT?SS???TTT??HHHHHHHHTS?GGGTTHHHHTT??????GGG??HHHHHHHHHHHHHHHHHHHT 2L1N|A PF08854.5_DUF1824_seed 23 139 !Q:9,9|12,20|66,86|89,89|100,101|107,108|110,111|120,120|126,127|134,134 Q:0,8|10,11|21,65|87,88|90,99|102,106|109,109|112,119|121,125|128,133|135,138 HHHHHTTTT?SB?----????HHHHHHHHHHHHHHHHTSSEEEEEEEESSHHHHHHHHHHHHHHTT???------???-----????SS-SEEEEEETTT??EEEEE??S??BEEEEEEE?SSTTS??EEEEEE?TTTT 2Q22|A PF08857.6_ParBc_2_seed 15 257 !Q:9,9|11,11|17,17|30,49|51,64|67,67|71,111|116,116|120,121|125,125|127,127|139,140|142,158|167,167|171,172|185,186|188,188|190,190|193,195|197,198|203,203|208,215|217,217|220,220|236,238|240,241 Q:0,8|10,10|12,16|18,29|50,50|65,66|68,70|112,115|117,119|122,124|126,126|128,138|141,141|159,166|168,170|173,184|187,187|189,189|191,192|196,196|199,202|204,207|216,216|218,219|221,235|239,239|242,256 BEEEEEGGG?B?SBSEE?HHHHHHHHHHHH--------------------T???-?????----?TT?BEE-----------------------------------------EEEE?STT-?EEE?S?HHHHHHHHHTT??E-----------------EEEEEEEE?TTS-?HHHHHHHHHHTT??B?B?TT??-B??GGGS?SSGG--------G?EE?HHHHHHHHHHHHTSS???S--STTHHHHHHHHHHTT 2HWJ|A PF08858.5_IDEAL_seed 42 42 !Q:7,11|30,30 Q:0,6|12,29|31,41 HHHHHHH-----HHHHHHHHHHHHHHHHTT?HHHHHHHHHHH 3DO9|A PF08860.5_DUF1827_seed 15 105 !Q:0,1|5,5|9,9|21,28|30,30|58,58|62,64|80,81|86,86|89,90 Q:2,4|6,8|10,20|29,29|31,57|59,61|65,79|82,85|87,88|91,104 ??EEE?GGG?HHHHHHHHHHS--------S?SEEEEEEETTEEEEEEEETTEEEEEEE?SSS???HHHHHHHHHHHHHHT??GGGB?TT??EEEEETTEEEEEEE 2QZI|A PF08864.5_UPF0302_seed 21 109 !Q:12,13|29,29|39,39|41,41|57,57|59,59|68,68|71,72|84,84|87,87|94,94|97,99|103,103 Q:0,11|14,28|30,38|40,40|42,56|58,58|60,67|69,70|73,83|85,86|88,93|95,96|100,102|104,108 HHHHHHHHHHHH??BSSTHHHHHHHHHHH?TTTTTTEEE?S?GGGSTEEEEEEBSSS?S?SEEEEESS?EE??HHHHHHHHHHH?SS?EEEEEE?SS---GGG?HHHHH 3DO9|A PF08866.5_DUF1831_seed 22 113 !Q:0,0|5,5|8,9|12,12|14,15|19,19|22,23|32,32|35,35|39,39|48,48|53,54|63,63|68,68|82,83|85,85|89,90 Q:1,4|6,7|10,11|13,13|16,18|20,21|24,31|33,34|36,38|40,47|49,52|55,62|64,67|69,81|84,84|86,88|91,112 ?SSBS-EE??TT?S??EEE?TT??HHHHHHTT?EE?TTS?EEEEEEES?SSTT??SEEEEEEE?TTSS?EEEEEEETTSSSB??S?GGG??HHHHHHHHHHHHHHHHTTSEEE 2IAY|A PF08868.5_YugN_seed 26 143 !Q:1,2|9,9|25,25|29,29|32,32|46,46|49,50|64,64|75,77|86,119|124,125 Q:0,0|3,8|10,24|26,28|30,31|33,45|47,48|51,63|65,74|78,85|120,123|126,142 E??SSSGGG?EEEHHHHHHHHHHTT?EEE?TT?SSEEEEEEEEEET-TE--EEEEEEEEEEEEE?TTSSSEEEEE???EEEEEETT??????------------------------????EEHH--HHHHHHHHHHHHHHHHH 2PWW|A PF08869.6_XisI_seed 34 134 !Q:0,1|5,5|25,25|28,31|33,44|53,60|96,97|100,100|110,111|121,121|132,133 Q:2,4|6,24|26,27|32,32|45,52|61,95|98,99|101,109|112,120|122,131 ??THH-HHHHHHHHHHHHHHHHHTT?SS????E------------EEEEETTT--------TEEEEEEEEEETTEEEEEEEEEEEEETTEEEEEEE??SS?HHHHHHHTT??GGGEEETTS?GGGGGGSSSB?? 2NLV|A PF08870.6_DUF1832_seed 23 136 !Q:2,4|20,21|23,23|39,42|45,47|49,55|58,58|60,61|68,72|87,93|96,98|119,135 Q:0,1|5,19|22,22|24,38|43,44|48,48|56,57|59,59|62,67|73,86|94,95|99,118 EE???HHHHHHHHHHHHHSS??H-HHHHHHHHHHHHTSS????TT---S???????SB?E--EHHHHH-----GGGHHHHHHHHHHH?------TT?-?HHHHHHHHHHHHHHHHHTTB??--------------- 4LRV|A PF08881.5_CVNH_seed 34 195 !Q:5,5|8,16|31,31|33,36|53,60|70,75|77,77|83,83|86,87|97,98|108,109|113,115|124,125|128,133|136,137|142,143|151,155|168,168|177,177|179,179|181,181|191,191 Q:0,4|6,7|17,30|32,32|37,52|61,69|76,76|78,82|84,85|88,96|99,107|110,112|116,123|126,127|134,135|138,141|144,150|156,167|169,176|178,178|180,180|182,190|192,194 BGGGT?BS???------BTTEEEEEEEETTT-E----EEEEEEEGGGTEEESS--------SSEEETTTT--????S?EEEEE?TT??HHHHHHHTT??HHHHHHHHT??GGG???TTEEEEES??SS------SS??GGGG--EEEEEEE-----TTTTEEEEEEEE-TTEEEEEE-E?G-GGTEEESSS?EEE 3LHC|A PF08883.6_DOPA_dioxygen_seed 44 128 !Q:7,11|32,37|41,45|48,51|53,54|57,57|59,61|70,71|86,86|89,90|98,98|100,103|110,110|113,113|118,123 Q:0,6|12,31|38,40|46,47|52,52|55,56|58,58|62,69|72,85|87,88|91,97|99,99|104,109|111,112|114,117|124,127 EEEEEEE---?-GGGHHHHHHHHHHHHHHTTT-----?SEE?--??BS----S??TT?S---SEEEEEEE-?HHHHHHHHHHHHHH?TT??EEEEEES-S?---HHHHHH-HS?EEES??????GGGG 2PEB|A PF08884.6_Flagellin_D3_seed 34 121 !Q:7,7|9,11|18,31|34,36|38,38|45,45|66,69|72,73|81,81|83,87|90,90|98,98|101,102|107,107|109,111|113,114 Q:0,6|8,8|12,17|32,33|37,37|39,44|46,65|70,71|74,80|82,82|88,89|91,97|99,100|103,106|108,108|112,112|115,120 EEEEEEE?B--?TTSTTT?-------------GG---G?SSEEEE?SSEEEETTTTEEEEEEEEET?---SS??EEEEEEE?T-----TT?BEEESTT?SS??TTSS?T---T??EEESEE 1UCU|A PF08886.6_GshA_seed 27 436 !Q:22,24|34,34|37,37|47,49|54,54|72,72|77,77|85,85|87,87|90,90|109,109|116,117|120,121|123,123|128,128|132,132|139,139|142,144|152,152|157,157|165,166|169,171|177,178|185,187|194,194|215,216|221,223|229,231|261,262|264,266|273,273|277,277|292,293|302,302|308,310|317,321|327,328|352,353|361,362|365,365|371,372|374,374|377,379|383,384|389,412 Q:0,21|25,33|35,36|38,46|50,53|55,71|73,76|78,84|86,86|88,89|91,108|110,115|118,119|122,122|124,127|129,131|133,138|140,141|145,151|153,156|158,164|167,168|172,176|179,184|188,193|195,214|217,220|224,228|232,260|263,263|267,272|274,276|278,291|294,301|303,307|311,316|322,326|329,351|354,360|363,364|366,370|373,373|375,376|380,382|385,388|413,435 HHHHHTSHHHHHHHHHHHHHHH???SEEEEEEEE?SS?EEEEEEESS???GGGS?GGGHHHHHHHHHHHHHH-HSTT?SEEEEEE?S?SS?HHHHHHHHHHHHHHHHTT?EEEEEE??TT??S?EEEE?SSS?EEEEEE?EE---ETTEEEE-TTEE?SEEEEES??TT???GGGSS?-SSEEES???TTGGGS?TTHHHHHHHHHHHHHHHHHT??GGGG???EEEEE???TTSSTTHHHHHHHHHHHHHHHHHHHHHHT??S???EEEEEE?GGG?EEEEEESSGGGGSS??HHHHHHHH?SSSSS???EEEEEE?????EEETT--EEEEEEEEEETTEEEEEEEEEES??STTTTTS??TT?EEEEE??S?SS???TTS?-TTSH------------------------HHHHHHHHHHHHHHHHHHHHHHH 3K1T|A PF08888.6_HopJ_seed 39 129 !Q:0,8|12,14|22,22|26,27|42,45|50,50|52,54|58,58|77,78|97,97|100,103|111,111|113,115|126,127 Q:9,11|15,21|23,25|28,41|46,49|51,51|55,57|59,76|79,96|98,99|104,110|112,112|116,125|128,128 ?-------?HHH---HHHHHHH?GGG??HHHHHHHHHHHEEE????EEET-T---EEE?TTSSHHHHHHHHHHHHTT??HHHHHHTTTHHHHTTTTS?TT????HHHHHHH-H---HTGGGEEESB??E 2QM2|A PF08890.6_XkdN_seed 23 164 !Q:0,0|4,6|13,17|19,20|22,22|24,26|29,29|31,31|35,35|37,38|42,45|58,76|78,78|95,99|102,102|111,111|113,113|116,116|123,125|127,127|145,163 Q:1,3|7,12|18,18|21,21|23,23|27,28|30,30|32,34|36,36|39,41|46,57|77,77|79,94|100,101|103,110|112,112|114,115|117,122|126,126|128,144 ?GGG---GSTTTS?????E--E-E???TT?B?TTS?B??EEE????HHHHHHHHHHTB???????------??????B?HHHHHHHHHHHHEEES?----TT?HHHHHHTT?S?HH-HHHHHH---T?SHHHHHHHHHHHHHHTT?-??????---???--??? 3KLU|A PF08903.6_DUF1846_seed 22 508 !Q:0,2|4,4|32,32|34,34|37,38|48,49|79,79|104,104|114,115|118,118|133,133|138,141|147,147|161,166|174,174|180,180|197,198|205,206|209,209|213,213|226,227|236,236|245,247|270,270|272,272|274,274|282,284|288,288|291,291|318,320|336,337|355,366|369,369|375,375|379,381|387,388|392,392|408,409|412,414|416,416|432,433|435,437|439,439|454,454|470,470|477,479|491,491|496,496|498,507 Q:3,3|5,31|33,33|35,36|39,47|50,78|80,103|105,113|116,117|119,132|134,137|142,146|148,160|167,173|175,179|181,196|199,204|207,208|210,212|214,225|228,235|237,244|248,269|271,271|273,273|275,281|285,287|289,290|292,317|321,335|338,354|367,368|370,374|376,378|382,386|389,391|393,407|410,411|415,415|417,431|434,434|438,438|440,453|455,469|471,476|480,490|492,495|497,497 ???B?HHHHHHHHHHHHHHHHHHTTSEEEEEE?S?SS??HHHHHHSTT??TTHHHHHHHTTGGGEEEEEEEEHHHHTTT?EETTTTEEHHHHHHHHHHHHHHTT?EEEEEEEES??TT?HHHHHHHHHHHTTT?EEEE????TTTTT?HHHHSSTTTGGGS??????SSEEEEE?SSTTS?HHHHHHHHHHHHHHTT??EEEEEE??SS?TTS?TTSHHHHHHHHT??SGGGSEEE?HHHHHHHS???EEEHHHHHHHHHHHHHHHHHHS-S?S?SSHHHHB???GGG?BS?HHHHHHHHHHHHHHHHHHHHHHHHHH???SHHHHHHHHHHHHHT??GGGSTTHHHHHHHHHHH------------SS?EEEEE?TTS--?EEEEE??SSB?HHHHHHHHHHHHHHT??TT???S?HHHHHHHHHHHHHTS??S???B?HHHHHHHHHHHTTT?HHHHHHHTTGGGGTT?EEEESS???HHHHHHHHHTT?EEEE?S?????-???? 3BH1|A PF08910.5_Aida_N_seed 8 110 !Q:19,19|40,40|44,45|48,48|71,75|77,79|81,82|99,101|103,104|107,109 Q:0,18|20,39|41,43|46,47|49,70|76,76|80,80|83,98|102,102|105,106 HHHHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHHHHHHT?SSS??SS?HHHHHHHHHHHHHHHHHHHHHH?---?S???S??SHHHHTHHHHHHTTTT??-S??SS??? 1UG7|A PF08911.6_NUP50_seed 35 88 !Q:0,4|7,9|14,15|18,31|33,34|42,87 Q:5,6|10,13|16,17|32,32|35,41 ?????SS???TTTS--SS?--??-????????B??HHHHHHS?????????----??-----------???????????????????? 2C1T|C PF08912.6_Rho_Binding_seed 22 74 !Q:0,0|46,48|54,55|71,73 Q:1,45|49,53|56,70 -HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHH--HHHHHHHHHHHHHHH??? 1S1C|X PF08913.5_VBS_seed 22 187 !Q:0,0|29,29|63,124|153,153|156,156|185,186 Q:1,28|30,62|125,152|154,155|157,184 ?HHHHHHHHHHHHHHHHHHHHHHHHHHHH?GGGHHHHHHHHHHHHHHHHHHHHHHHHHSSSHH--------------------------------------------------------------HHHHHHHHHHHHHHHHHHHHHHHHHHHH?TT?HHHHHHHHHHHHHHHHHHHHHHHHHTTS?? 1XWJ|B PF08914.6_Myb_DNA-bind_2_seed 11 66 !Q:0,5|20,21|24,24|40,40|44,45|58,65 Q:6,19|22,23|25,39|41,43|46,57 ??????HHHHHHHHHHHHHT??ST-TTTTSSHHHHHHHHS?SSS??SHHHHHHHHHHT??------ 1FEX|A PF08915.6_tRNA-Thr_ED_seed 35 146 !Q:0,0|22,26|44,44|51,51|72,72|75,76|82,82|86,86|90,91|104,106|110,111|116,116|121,122|134,134|145,146 Q:1,21|27,43|45,50|52,71|73,74|77,81|83,85|87,89|92,103|107,109|112,115|117,120|123,133|135,144 ?EEEEEEEEEEEEEEEEESSSS?????GGGGEEEEEEEEEEEEE?BGGGGG?HHHHHHHHHHHHHHHHHHTT?SE--EEEEE?SSS?SSB??HHHHHHHHHHHH---HHH--HHTT?EEEE??TTEEEEEEEEE?SSTTSEEEEE?- 3PD5|A PF08916.6_Phe_ZIP_seed 7 61 !Q:0,1|28,30|34,34 Q:2,27|31,33|35,60 ??HHHHHHHHHHHHHHHHHHHHHHHHHH?--GGG?STTHHHHHHHHHHHHHHHHHHHHHHH 1Q2H|A PF08917.5_ecTbetaR2_seed 6 120 !Q:0,2|5,6|12,15|17,17|20,20|22,27|30,31|35,36|54,56|60,60|65,66|68,68|74,74|76,76|80,81|95,95|101,101|103,119 Q:3,4|7,11|16,16|18,19|21,21|28,29|32,34|37,53|57,59|61,64|67,67|69,73|75,75|77,79|82,94|96,100|102,102 ???EE??EEEEE????S?SS?B??????EE??SSS??EEEEEEEETTEEEEEEE???TTS?BTTB??S?SSSSS?B?EEE??SSSEEEEEEESSS-STTTB?B??-------------?? 1KS6|A PF08918.5_PhoQ_Sensor_seed 10 185 !Q:0,35|56,56|59,59|63,65|68,69|71,72|80,80|84,84|91,92|100,100|124,125|134,136|144,144|147,147|159,160|165,166|176,176|181,181|183,184 Q:36,55|57,58|60,62|66,67|70,70|73,79|81,83|85,90|93,99|101,123|126,133|137,143|145,146|148,158|161,164|167,175|177,180|182,182 -----------------------------------?HHHHHHHHHHHHHHHHHEEE?SS?EEE???TT??S??SEEEEEE?TTS?EEEESS??HHHHHHS?GGGGGSSEEEEEEEEHHHHHHHS-?TTSTHHHH---HHHHHHH?TT?EEEEEEEEEEE??BTTB??EEEEEEESS?GGGS?S?? 3BQA|A PF08919.5_F_actin_bind_seed 16 133 !Q:0,0|5,6|24,26|28,48|69,70|72,72|96,97|99,99|104,109|112,113|132,132 Q:1,4|7,23|27,27|49,68|71,71|73,95|98,98|100,103|110,111|114,131 ?HHHH??HHHHHHHHHHHHHHTTS???H---------------------HHHHHHHHHHHHHHHHHGGG-?S?HHHHHHHHHHHHHHHHHHHHHHH--S?SSSS-----?TT??THHHHHHHHHHHHHHHHH? 1ZZP|A PF08921.6_DUF1904_seed 20 110 !Q:0,1|9,9|30,31|35,35|40,46|49,55|63,65|85,86|89,91|98,99|103,103 Q:2,8|10,29|32,34|36,39|47,48|56,62|66,84|87,88|92,97|100,102|104,109 ??EEEEESS?HHHHHHHHHHHHHHHHHHHT??GGG?EEEE???????TT??---??EEEEEES???HHHHHHHHHHHHHHHHHHH-?TT???EEEEEE??GGG?EETTEE 1U9D|A PF08922.6_DUF1905_seed 48 110 !Q:4,4|6,8|10,10|12,12|14,17|19,19|24,25|27,27|33,34|36,49|51,51|66,66|71,72|77,83|89,89|98,100 Q:0,3|5,5|9,9|11,11|13,13|18,18|20,23|26,26|28,32|35,35|50,50|52,65|67,70|73,76|84,88|90,97|101,109 EEEE?E---E?T-T?---S?EEEE??S?HHHHH?-S--------------S?EEEEEEETTEEEEE-EEEE--SSTT------?EEEEE?HHHHHHHT?-?TTSEEEEEE 2D9R|A PF08923.5_MAPKK1_Int_seed 7 133 !Q:7,7|18,20|27,27|30,31|38,38|42,43|68,69|87,91|106,106|122,125|128,132 Q:0,6|8,17|21,26|28,29|32,37|39,41|44,67|70,86|92,105|107,121|126,127 HHHHHHH-HHHGGGSTTE---EEEEEE?TT??EEEEEE?TTS-?GGGGSHHHHHHHHHHHHHHTTSSS??EEEEEEEESSEEEEEEE-----ETTEEEEEEEETTS?HHHHHHHHHHHHHHH----HS????? 1VEU|A PF08924.6_DUF1906_seed 35 160 !Q:0,0|3,6|18,20|29,29|35,42|44,45|57,57|64,80|82,82|84,85|105,106|109,109|115,116|120,120|122,122|125,131|143,146|149,153 Q:1,2|7,17|21,28|30,34|43,43|46,56|58,63|81,81|83,83|86,104|107,108|110,114|117,119|121,121|123,124|132,142|147,148|154,159 ?SS??-?HHHHHHHHHHT???SEEEEESS?BTTTB?-------B??HHHHHHHHHTT?EEEEEE??--------------?S?B??HHHHHHHHHHHHHHHHHTT??SS?EEEEE??TTS?B?HH-------HHHHHHHHHHH----HT----?EEEEEE 1SFS|A PF08925.6_DUF1907_seed 14 323 !Q:19,21|28,29|33,34|38,38|45,45|53,53|57,57|68,68|71,75|78,78|80,81|88,89|96,97|101,101|105,121|126,127|130,131|137,137|142,142|152,153|155,155|167,169|171,172|183,183|186,188|204,205|207,208|226,227|230,234|237,239|245,245|257,257|268,271|274,276|284,285|289,292|300,303|307,307|316,316 Q:0,18|22,27|30,32|35,37|39,44|46,52|54,56|58,67|69,70|76,77|79,79|82,87|90,95|98,100|102,104|122,125|128,129|132,136|138,141|143,151|154,154|156,166|170,170|173,182|184,185|189,203|206,206|209,225|228,229|235,236|240,244|246,256|258,267|272,273|277,283|286,288|293,299|304,306|308,315|317,322 HHHHHHHHHEEEEEEEEEE???TTSTTT??SSS??BSS?EEEEEE?GGGTSSS?BTT?EEEHHHHHHH-TT?----TT?E--EEEEEE??HHHHSS??EEE?EEE??---------------BTTB??EE??EEEEE?TTTS?EEEEEHHHH??S?EEEEEEEEEEE??-B??EEEEEEEEEE?SS?-?HHHHHHHHHHHHHTT--S??EEEEEEEEEESEEEEEE??SS?---?SS???SHHHH-HHHSEEEEEES?EEEEEEEESS??--SS???SEEEEEE?-SSS?--?EEEEEES---?TTT?EEEEEEEE?SEEEEE 1XCR|A PF08926.6_DUF1908_seed 6 379 !Q:0,42|45,56|58,226|243,245|251,252|254,254|279,281|304,304|325,376 Q:43,44|57,57|227,242|246,250|253,253|255,278|282,303|305,324|377,378 ------------------------------------------?SS-----------?S-------------------------------------------------------------------------------------------------------------?---------------------------------------------------------??TTHHHHHHHHHHHHHS?--BTTTB??S?HHHHHHHHHHHHHHHHHHHHHHHT???HHHHHHHHHHHHHHHHHHHHTS?HHHHHHHHHHHHHHHHHHSS???------------------------------------------------?SS 1V9V|A PF08929.5_DUF1911_seed 20 138 !Q:2,7|19,20|22,24|26,30|32,32|44,48|50,55|64,64|75,75|80,91|96,101|108,109|120,123|132,134 Q:0,1|8,18|21,21|25,25|31,31|33,43|49,49|56,63|65,74|76,79|92,95|102,107|110,119|124,131|135,137 TT?---??HHHHHHHHHHH??S---S?????S?HHHHGGGHHHH-----H??????GGGGHHHH-HHHTHHHHTS?HHHH------------HHTT???--?TTTTTT??HHHHHHHHHH????HHHHTSTT-??HHH 2FEF|A PF08930.5_DUF1912_seed 17 84 !Q:0,1|32,37|68,69|73,83 Q:2,31|38,67|70,72 ??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHT??TTS??????????? 1Z0P|A PF08931.5_DUF1913_seed 5 146 !Q:0,1|5,18|32,33|36,37|44,45|48,48|75,76|88,88|91,91|94,95|104,110|115,115|117,117|128,128|138,140|144,144|146,146 Q:2,4|19,31|34,35|38,43|46,47|49,74|77,87|89,90|92,93|96,103|111,114|116,116|118,127|129,137|141,143|145,145 ??EEE??????????????HHHHHHHHHHHHT??TT??EEEEEE??EE?SSEEEEEEEEEEETTEEEEEEEEEEE??TTSEEEEEEEE?TT?SS??EEEEEESS???????TTTS?S?EEEEEEEEEE?SSSEEEEEE???EEE?S- 2X53|A PF08932.5_DUF1914_seed 9 137 !Q:0,17|24,26|53,56|59,59|64,64|67,70|74,77|80,80|82,82|89,97|102,102|109,109|113,113|117,117|119,120|122,122|125,125|136,136 Q:18,23|27,52|57,58|60,63|65,66|71,73|78,79|81,81|83,88|98,101|103,108|110,112|114,116|118,118|121,121|123,124|126,135 ???????---????????EEEEEE---EEETTEEEEEEEETTTEEEEEEEEEE---?SB?TTBB?SS????GGG?--?SS?E-EEEEEE---------TTSS?EEEEEE?TTS?EEE?S??B?SS?EEEEEEEEEE? 2BSE|A PF08933.6_DUF1864_seed 11 397 !Q:0,1|33,34|38,38|63,65|90,90|94,94|97,97|99,99|116,116|119,120|128,129|136,137|139,141|172,172|204,204|217,218|227,230|233,233|248,248|266,266|280,281|296,297|328,359|373,376|380,381|388,390|397,397 Q:2,32|35,37|39,62|66,89|91,93|95,96|98,98|100,115|117,118|121,127|130,135|138,138|142,171|173,203|205,216|219,226|231,232|234,247|249,265|267,279|282,295|298,327|360,372|377,379|382,387|391,396 ??HHHHHHHHHHTHHHHHHHHHHHHHHHSSSSS??SSS?HHHHHHHHHHHHHHHHTTTTTSSS???HHHHHHHHHHHHHHHHHHHHTTSS?TTT?SS?S?HHHHHHHHHHHHHHTS?SS??HHHHTTT??EETTEE??S???HHHHHHHHHHHHHHHHHHHHHHHHHTTTTT?TTSHHHHHHHHHHHHHHHHHHHHHHHHHTTS?HHHHHHHTGGGG??EEETTEEE????TT?SHHHHHHHHHTTSS?TTSHHHHHHHHTTGGGS?HHHHHHHHHHTTS??HHHHHHHTGGGGGS--HHHHHHHHHHHHHHHHHHHHHHHHHHHHTS?????????????????----???????????HHHHHHHHHHHTT??-?SSS??THHHHH---HHHHHT- 2V7K|A PF08935.5_VP4_2_seed 12 85 !Q:0,15|17,19|22,23|26,26|32,65|74,74|76,76|78,78|81,84 Q:16,16|20,21|24,25|27,31|66,73|75,75|77,77|79,80 ????????????????S???SS??SS?HHHHS??????????????????????????????????THHHHHHT?B?S?SS???? 3CJI|D PF08936.5_CsoSCA_seed 22 480 !Q:0,0|3,4|36,36|40,41|56,58|63,64|71,71|75,80|98,110|131,131|135,135|147,152|158,159|164,166|185,186|189,189|194,194|205,205|214,214|220,220|247,248|267,269|273,275|278,278|293,293|311,312|316,317|320,322|351,352|358,360|368,369|372,374|383,383|385,385|409,410|420,420|453,453|462,463|469,470|475,479 Q:1,2|5,35|37,39|42,55|59,62|65,70|72,74|81,97|111,130|132,134|136,146|153,157|160,163|167,184|187,188|190,193|195,204|206,213|215,219|221,246|249,266|270,272|276,277|279,292|294,310|313,315|318,319|323,350|353,357|361,367|370,371|375,382|384,384|386,408|411,419|421,452|454,461|464,468|471,474 ?TT??HHHHHHHHHHHHHHHHHHHTHHHHHHHHHHS?SSS??HHHHHHHHHHHHSS???GGGS??BTTTBS?HHH------HHHHHHHHHHHHHHHHT????????----?HHHHHHHHHHHHTEEEEEEE-EBS?GGGTTIIIIII??-???TTEEE??BGGG???HHHHHHHHHHHHHHHHHH??SS?TTSS?EEEEEEEEEE?SSSTTTSS?GGGTT?HHHHHHHHHHHHHHHHHHHHHHSSTT??EEEEEEEEETTTTEEEEE???TTS???TT?EEEHHHHHHHHTTS?HHHHHHHHHHHHHHHHT??GGG??SS???HHHHHHHHHHHHHHHHHHHHHHHHHSSS??GGGTS???SEEEEES??SS???TTTEEEEE?S?TGGGHHHHHHHHHHHHHHTGGGT??EEEEEEEEE?TTSTTHHHHHHHHHHHHHHHHHHHTHHHHHTT?EEEEEEEE--ESSTT??EEEE?---? 2FGY|A PF08937.6_DUF1863_seed 55 229 !Q:0,6|13,15|19,26|35,41|45,47|49,50|56,63|67,69|79,79|93,94|97,110|119,175|181,188|190,192|200,201|203,204|206,217|222,222|226,226|228,228 Q:7,12|16,18|27,34|42,44|48,48|51,55|64,66|70,78|80,92|95,96|111,118|176,180|189,189|193,199|202,202|205,205|218,221|223,225|227,227 -------GSTTHH---HHH--------HHHHHHHH?------TTS---S??BTTTT??-----?TTS???TTTTHHHHH-HHHHHTEEEEEEE??TT?-??---------?HHHHHHHH---------------------------------------------------------HHTTT--------T???EEEEETT??S--G------------GGTB?TTS?B? 3HYN|A PF08938.5_HBS1_N_seed 47 149 !Q:0,84|92,92|95,96|109,114|128,128|141,141|145,148 Q:85,91|93,94|97,108|115,127|129,140|142,144 ?????--------------------------------------------------?????--------------------?????TTHHHHH-HT??STTHHHHHHHHH??---?SSHHHHHHHHTTT?SSHHHHHHHHTT?SSS???? 3IZQ|1 PF08939.5_DUF1917_seed 20 329 !Q:0,5|18,63|65,66|68,69|78,97|109,109|114,154|158,159|164,164|167,168|170,170|175,175|178,184|199,203|216,218|226,226|244,244|248,249|255,264|266,266|270,271|280,286|289,289|304,304|306,307|309,314|323,324 Q:6,17|64,64|67,67|70,77|98,108|110,113|155,157|160,163|165,166|169,169|171,174|176,177|185,198|204,215|219,225|227,243|245,247|250,254|265,265|267,269|272,279|287,288|290,303|305,305|308,308|315,322|325,328 ??????GGGSHHHHHHHT??--------------------------------------------S??S??EEEETTTS?-------------------GGGHHHHHHHS?TTTS-----------------------------------------BTT??TTSS?SS??S?EEEE?TT???????HHHHHHHHHHHHHH?????HHHHHHHHHHHT???EEEEEEE?SSHHHHHHHHHHHHHHH-HTS?-SEEEE??--------B?SSS??EEEEEEES------?TT?HHHHHHHHHHHHHT-T??S-----?EEEEEHHH--HHTT 1ZTP|A PF08940.6_DUF1918_seed 18 60 !Q:0,3|12,12|17,18|27,27|29,29|33,33|35,35|50,54|57,57 Q:4,11|13,16|19,26|28,28|30,32|34,34|36,49|55,56|58,59 ????TTEEEEES?TTTS??EEEEEEEE?S?SSS?S?EEEEETTTTEEEEE???--SS?EE 2A7Y|A PF08941.5_USP8_interact_seed 5 195 !Q:0,47|49,49|51,63|71,72|87,88|96,97|113,114|131,131|150,151|155,155|157,160|172,172|176,176|180,181|192,192|195,195 Q:48,48|50,50|64,70|73,86|89,95|98,112|115,130|132,149|152,154|156,156|161,171|173,175|177,179|182,191|193,194 ------------------????????????------------------S?T-------------TSHHHHH--HHHHHHHHSEEEEE??GGGEESS??HHHHHHHHHHHHHTT??HHHHHHHHHTTSGGGS?TTTSSHHHHHHTTTGGGG??EEE?T----TSSEEEEEGGG?TTS?TTT??SSEEEEEESS?EE- 2GWF|B PF08942.5_DUF1919_seed 15 244 !Q:9,10|16,16|25,26|37,39|41,41|59,62|65,66|70,71|89,94|97,98|101,111|116,117|122,123|127,127|133,133|135,135|152,153|163,164|166,168|180,180|187,187|190,195|197,197|202,204|206,209|211,215|223,223|226,226|228,228|231,231|238,238 Q:0,8|11,15|17,24|27,36|40,40|42,58|63,64|67,69|72,88|95,96|99,100|112,115|118,121|124,126|128,132|134,134|136,151|154,162|165,165|169,179|181,186|188,189|196,196|198,201|205,205|210,210|216,222|224,225|227,227|229,230|232,237|239,243 HHHHHHHTT??GGGEE?SGGGGSTT??HHHHHHHHHT---T?EEEESSSHHHHHHHHHT????SS??SEE??HHHHHHHHHSHHHHHHS?--???SB??BG-----------GGTB??EEEE??STT?EEEEE?S?SSHHHHHHHHHHHGGG??TTSEEEEEE??S?-?HHHHHHHHTSS?SSEEEE?SS----??S-STTB???H----H-----HHHHHHH?TT?S?SS?HHHHTT?HHHHH 2G6T|A PF08943.5_CsiD_seed 11 303 !Q:6,6|9,9|18,18|33,33|40,40|58,58|69,69|72,73|82,83|87,92|112,113|127,135|138,138|141,142|147,147|149,149|155,157|169,170|172,173|182,182|197,197|201,202|205,205|208,211|215,215|217,217|221,221|225,225|229,231|237,238|256,256|259,259|263,265|268,268|282,283|285,287|290,290|302,302 Q:0,5|7,8|10,17|19,32|34,39|41,57|59,68|70,71|74,81|84,86|93,111|114,126|136,137|139,140|143,146|148,148|150,154|158,168|171,171|174,181|183,196|198,200|203,204|206,207|212,214|216,216|218,220|222,224|226,228|232,236|239,255|257,258|260,262|266,267|269,281|284,284|288,289|291,301 SEEEEE?SS?TTEEEEEE?HHHHHHHHHHHTTS?HHHHHH?THHHHHHHHHHHHHTTT?HHHHHHHHHH?TT??EEEEEETT??SGG------GHHHHHHHHHHHHHHHEEE??BTTTTBSSEEEEE?????????TT?TT??EEEE?S?TTSSS???EEEEEEEEEES??B??EEEEEGGG?TTHHHHHTSGGGGS?EEE??SS?TT????EEE?S-EEE?TTS?EEE???TTTEE??SHHHHHHHHHHHHHHHT?TT?EEE???TT?EEEEETTTEEEEE??B???TT?EEEEEEEEEEE? 1JR7|A PF08944.6_p47_phox_C_seed 12 64 !Q:0,41|50,50|57,63 Q:42,49|51,56 ------------------------------????????????HHHHHHSS?HHHHHH??--??? 1K4U|P PF08945.5_Bclx_interact_seed 6 43 !Q:0,15|36,39|41,42 Q:16,35|40,40 ----------???-??HHHHHHHHHHHHHHHHHHHH----S?? 3KZ0|C PF08946.5_Osmo_CC_seed 10 46 !Q:0,13|41,46 Q:14,40 --------------THHHHHHHHHHHHHHHHHHHHHHHHHH???--- 1R48|A PF08947.5_BPS_seed 4 50 !Q:0,7|12,12|17,19|21,23|40,49 Q:8,11|13,16|20,20|24,39 ????????EEEE?SSSS-??B???HHHHHHHHHHHHHHHH?????????? 2AUH|B PF08948.5_DUF1859_seed 2 126 !Q:0,14|17,18|21,22|25,26|33,33|37,40|44,48|53,53|56,57|59,59|64,65|69,70|75,75|78,78|81,86|89,90|94,95|110,113|115,125 Q:15,16|19,20|23,24|27,32|34,36|41,43|49,52|54,55|58,58|60,63|66,68|71,74|76,77|79,80|87,88|91,93|96,109|114,114 ???????????????TT??SS??EE??EEESSS?EEE????TTT?????EEEE?TT??S?EEEE??TTS??EEEE?SS?EE??????SS??EEE??SSSSEEEEEEEESS????S??????????? 1W8X|N PF08949.5_DUF1860_seed 2 220 !Q:0,25|29,29|34,35|42,51|68,78|92,93|97,97|100,106|129,129|132,133|144,144|147,148|169,170|174,174|185,187|189,189|205,205|209,209|218,219 Q:26,28|30,33|36,41|52,67|79,91|94,96|98,99|107,128|130,131|134,143|145,146|149,168|171,173|175,184|188,188|190,204|206,208|210,217 --------------------??????SSS?STTT??SSSSTT??????????TTEEEEEETTEEEEEE?---------?SEEEEEEEETTTT??SSB?SS???????SSSEEEEEESSSEEEETTEEEE?TT??EEEEEEEEEE?TT??SSEEEEEEEETTEEEEEEEE??STT?EEEEEEEEEE???S?TTTSEEEEEEEETTB?BSS?EEEEEEEE?? 1YQ6|A PF08950.5_DUF1861_seed 12 307 !Q:7,11|17,17|22,22|25,25|30,33|48,48|51,51|54,55|71,71|74,76|79,79|99,110|120,120|130,131|134,137|142,142|146,146|152,162|170,170|174,174|182,183|187,192|207,207|217,228|238,238|242,243|252,252|257,261|278,278|282,282|300,301 Q:0,6|12,16|18,21|23,24|26,29|34,47|49,50|52,53|56,70|72,73|77,78|80,98|111,119|121,129|132,133|138,141|143,145|147,151|163,169|171,173|175,181|184,186|193,206|208,216|229,237|239,241|244,251|253,256|262,277|279,281|283,299|302,306 HHHHHHH--???SEEEE?EEES?TT?EEES????EEETTEEEEEEEEE?TT?SS??EEEEEEEEETTEEEE?TT-??BS?EEEEEEEETTEEEEEEEEE??---???????EEEEEEEEE-TTEEEEEEE??TT????EEEE?TTS?EEEEE?????--????EEEEEES?GGG?SHHHHHT??EES-?????EEEEEEEEEEETTS?EEEEEEEEE?-??????????EEEEEEEEE?TTT??EEEEEEEE?GGGS?????SSGGGTTBEEEEEEEE?TTS?EEEEEEETTTEEEEEEE??TTTTS 2B4W|A PF08951.5_EntA_Immun_seed 62 88 !Q:0,0|6,8|18,19|24,24|27,27|29,29|48,50|70,72|74,77 Q:1,5|9,17|20,23|25,26|28,28|30,47|51,69|73,73|78,87 ?HHHHH---HHHHHHHHH--HHTT?SS?S-STHHHHHHHHHHHHSSSS?--HHHHHHHHHHHHHHHHHHH---T????HHHHHHHHHH 1TDP|A PF08952.6_DUF1866_seed 6 156 !Q:0,18|20,24|27,27|36,45|52,53|69,70|84,84|86,86|109,131|133,155 Q:19,19|25,26|28,35|46,51|54,68|71,83|85,85|87,108|132,132 -------------------S?????TT?EEEEEESS--------??HHHHHS??HHHHHHHHHHHHHHS??SEEEEETTEEEEE?S?SHHHHHHHHGGGSEETTEEEEE-----------------------E?--------------????---- 2DNR|A PF08953.6_DUF1899_seed 33 69 !Q:0,7|9,11|13,13|18,19|27,28|30,34|37,37|42,42|51,52|56,57|65,67 Q:8,8|12,12|14,17|20,26|29,29|35,36|38,41|43,50|53,55|58,64|68,68 ????????T---T?EEEE??GGGSEES??B?????SS?BEEE?SSEEEEEB??SSS??EEEEETT?-?E 2B4E|A PF08954.6_DUF1900_seed 64 181 !Q:0,0|4,4|7,11|13,13|32,32|34,34|41,43|46,48|59,60|63,64|66,90|94,94|96,97|102,102|115,115|118,119|121,126|134,140|143,144|148,150|153,153|155,155|157,157|160,160|166,166|169,176|179,179 Q:1,3|5,6|12,12|14,31|33,33|35,40|44,45|49,58|61,62|65,65|91,93|95,95|98,101|103,114|116,117|120,120|127,133|141,142|145,147|151,152|154,154|156,156|158,159|161,165|167,168|177,178|180,180 ?SEE-EE?????S?EEEEEETTTTEEEEEETT?S?EEEEEE--?SS---TTSEEEEEEE??SS??S-------------------------EEE-E??GGGS?GGGTEEEEEEEE?SS--E------EEEEEEE????-?-SS??GGG???EE?S-S?SB?HHHHH-TT????--??EE?S 2B4E|A PF08955.5_BofC_C_seed 10 76 !Q:2,3|9,11|27,27|32,32|35,41|46,46|56,57|59,61 Q:0,1|4,8|12,26|28,31|33,34|42,45|47,55|58,58|62,75 SS??TGGGT???EEEETTTEEEEBSSS?STTS?BS???????TTTS?HHHHHHHHH??S???HHHHHHHHHHHHHH 2BW2|A PF08956.5_DUF1869_seed 3 60 !Q:0,4|15,16|22,24|30,30|55,55|57,59 Q:5,14|17,21|25,29|31,54|56,56 ?????EEEEEEETTT??EEEEE???SGGGT?HHHHHHHHHHHHHHHHHTTSSSSS?S??? 1NEI|A PF08958.5_DUF1871_seed 7 79 !Q:10,10|15,15|33,33|35,35|54,56|75,78 Q:0,9|11,14|16,32|34,34|36,53|57,74 HHHHHHHHHH?TTSS?GGGGHHHHHHHHHHHTT?S?HHHHHHHHHHHHHHHHSS???HHHHHHHHHHHHHHHHHH???? 1U84|A PF08960.5_DUF1874_seed 12 123 !Q:0,7|14,17|19,19|23,25|32,32|41,44|48,48|52,52|54,54|69,71|73,78|80,80|83,83|93,95|98,102|108,113|116,116 Q:8,13|18,18|20,22|26,31|33,40|45,47|49,51|53,53|55,68|72,72|79,79|81,82|84,92|96,97|103,107|114,115|117,122 ?-------EEEESS????B?SSS???EEEEEE?HHHHHHHH----HHS?EEE?B?SHHHHHHHHHHHTS???B??????B?TT?EEEEEEESS???TT?????HHHHH------HH?EEEEEE 2J85|A PF08962.6_DUF1876_seed 6 88 !Q:0,7|14,14|17,17|26,26|39,41|45,47|80,87 Q:8,13|15,16|18,25|27,38|42,44|48,79 ????????EEEEEE?SS?EEEEEEEE-ETTEEEEEEEEE???SSS???SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS???????? 2FGG|A PF08963.5_DUF1878_seed 5 113 !Q:0,1|22,22|26,26|37,38|64,67|79,79|83,83|96,96|112,112 Q:2,21|23,25|27,36|39,63|68,78|80,82|84,95|97,111 ??THHHHHHHHHHHHHHHHTTS?TTT?HHHHHHHHTT??HHHHHHHHHHHHHHHHHHHHHHHTT????HHHHHHHHHHS?TTS?HHHHHHHHHHTT?SHHHHHHHHHHHHHH? 1SED|A PF08964.5_Crystall_3_seed 17 95 !Q:0,0|3,3|13,13|15,15|20,20|26,29|31,32|35,35|41,42|47,47|50,50|57,59|62,62|65,67|72,72|79,80|83,83|85,85|87,87|94,95 Q:1,2|4,12|14,14|16,19|21,25|30,30|33,34|36,40|43,46|48,49|51,56|60,61|63,64|68,71|73,78|81,82|84,84|86,86|88,93 ?TT?EEEESSTTT?S?EEEE?SSEEE----E??TT?HHHHT??EEEE?SS?EEEEES???SS?SS???EEEE?SSEEES??GG-G?S?SEEEEE?- 1HDF|A PF08965.5_DUF1870_seed 4 126 !Q:0,1|14,15|27,28|41,43|70,76|79,79|81,82|85,87|100,101|121,122|125,125 Q:2,13|16,26|29,40|44,69|77,78|80,80|83,84|88,99|102,120|123,124 ??HHHHHHHHHHTT??HHHHHHHTSSS??HHHHHHHHHTSS???HHHHHHHHHHHHHHHHHHHHHHHHHT-------TS?S??EE???SSHHHHHTTSTT??HHHHHHHHHHHHHHHHTTS?-EE? 1S4K|A PF08966.6_DUF1882_seed 10 74 !Q:0,7|9,12|14,14|19,19|23,23|36,36|41,41|43,45|58,58|66,66|73,73 Q:8,8|13,13|15,18|20,22|24,35|37,40|42,42|46,57|59,65|67,72 ????????S????S?EEEE?SSS?EEEEETTEEEEE?EEEE?S???HHHHHHHHTTSS?EEEESSB-TTTEES? 2ATZ|A PF08967.5_DUF1884_seed 7 97 !Q:0,1|3,4|27,30|35,35|52,57|67,67|78,78|88,88|94,97 Q:2,2|5,26|31,34|36,51|58,66|68,77|79,87|89,93 -?H--HHHHHHHHHHHHHHHHHHHHTT????EEEE?HHHHHHHHHHHHHHHT??????EETTEEEEE?GGGTTEEEEE?TTTTTTSTT?EEEEE???- 2PK8|A PF08968.5_DUF1885_seed 4 143 !Q:0,12|15,18|49,50|58,61|73,74|82,90|102,103|106,107|126,126|131,131|135,135|140,142 Q:13,14|19,48|51,57|62,72|75,81|91,101|104,105|108,125|127,130|132,134|136,139 ?--??????---?TT????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??EEEEEET----TEEEEEESSTT??EEEEEEE---------EETTEEEEEEE??TT??HHHHHHHHHHHHHHHHHH?EEEE?TTS?EEEE??? 1T6A|A PF08969.6_USP8_dimer_seed 25 129 !Q:0,6|8,12|23,25|30,31|35,41|61,61|77,77|98,98|107,107|110,113 Q:7,7|13,22|26,29|32,34|42,60|62,76|78,97|99,106|108,109|114,128 ???????S?----SSHHHHHGGG???GGGS-?HHH-------HHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHH-HHHTTSHHHHHTHHHHHHHH?HHHHHHHH-HH----HHHHHHHHHHHHHHH 2A9U|A PF08970.5_Sda_seed 18 49 !Q:0,0|3,5|7,7|23,24|40,40|44,48 Q:1,2|6,6|8,22|25,39|41,43 ?TT---S?HHHHHHHHHHHHHTT??HHHHHHHHHHHHHTT?GGG????? 3D36|C PF08971.6_GlgS_seed 4 67 !Q:0,2|26,29|37,38|63,63|65,66 Q:3,25|30,36|39,62|64,64 ?-?TTTTHHHHHHHHHHHHHHHHHHT????HHHHHHH??HHHHHHHHHHHHHHHHHHHHHTTS?S?? 1RRZ|A PF08972.6_DUF1902_seed 8 54 !Q:17,17|23,25|49,53 Q:0,16|18,22|26,48 EEEEEEEETTTTEEEEE?SSSTT???EESSHHHHHHHHHHHHHHHHHHS????? 1WV8|A PF08973.5_TM1506_seed 9 143 !Q:0,1|17,17|27,27|32,33|43,45|49,49|51,53|56,56|64,64|75,76|97,98|108,108|110,110|117,117|126,128|137,139 Q:2,16|18,26|28,31|34,42|46,48|50,50|54,55|57,63|65,74|77,96|99,107|109,109|111,116|118,125|129,136|140,142 -?HHHHHHHHHHHHHTT?SEEEESSSE-EEEE??STTHHHHHH---HHH?S?-?TT?EEEEEEE?HHHHHHHHHH??SEEEEEEEEHHHHHHHHHTT??EEEEEEESS?B?SSSSSB?HHHHHHHT???HHHHHHHH---HTT 1VK9|A PF08974.5_DUF1877_seed 16 217 !Q:0,3|10,10|19,20|22,40|51,77|81,81|84,84|96,96|99,105|107,108|111,111|119,119|121,122|126,126|128,132|134,134|139,139|153,154|162,163|172,172|175,180|210,210 Q:4,9|11,18|21,21|41,50|78,80|82,83|85,95|97,98|106,106|109,110|112,118|120,120|123,125|127,127|133,133|135,138|140,152|155,161|164,171|173,174|181,209|211,216 ????EEEEEE?HHHHHHHH--H?------------??????TTHHHHSTTB?--------------------------EEE?TT?HHHHHHHHHSS?TT-------S??TT?HHHHHHH?S--EEE-E?????E-EEEE?HHHHHHHHHHHHH??HHHHHHH??HHHHHHTT?TT?-????GGGHHHHHHHHHHHHHHHHHHHHHHHHTT?EEEEEE 1RYL|A PF08975.5_2H-phosphodiest_seed 13 128 !Q:2,2|6,6|8,11|20,20|28,30|51,52|56,56|68,69|75,75|79,79|82,83|98,107|111,116|122,122 Q:0,1|3,5|7,7|12,19|21,27|31,50|53,55|57,67|70,74|76,78|80,81|84,97|108,110|117,121|123,127 TB?TTS?B????EEEEEEEB?TTSHHHH---HHHHHHHHHHTSGGGGGEEE??GGG?EEEEEEEEETT??STTSS?TTS?TT??HHHHHHHHHHHGGG???--?????EEE------EEEET-TEEEE 2FSQ|A PF08976.6_DUF1880_seed 2 122 !Q:1,4|16,16|18,18|22,22|24,24|33,121 Q:0,0|5,15|17,17|19,21|23,23|25,32 T????HHHHHHHHTTS?B?TTS?B?HHHHHHHH???????-??????---??????------------------------------------------------------------------ 1WLZ|A PF08977.5_BOFC_N_seed 10 51 !Q:8,8|12,12 Q:0,7|9,11|13,50 EEEEEEEE?SSS?EEEEEEEEEEEEHHHHHHHSTTSEEEEEETTEEEEEEE 2BW2|A PF08978.5_Reoviridae_Vp9_seed 2 280 !Q:0,27|31,31|33,33|43,43|53,54|57,57|60,61|72,72|85,86|90,90|92,93|96,97|100,100|105,105|109,109|113,113|129,132|135,137|140,140|171,171|174,174|176,178|191,192|203,204|218,218|223,226|231,232|235,237|240,243|246,246|248,252|255,255|265,265 Q:28,30|32,32|34,42|44,52|55,56|58,59|62,71|73,84|87,89|91,91|94,95|98,99|101,104|106,108|110,112|114,128|133,134|138,139|141,170|172,173|175,175|179,190|193,202|205,217|219,222|227,230|233,234|238,239|244,245|247,247|253,254|256,264|266,279 ????????????????????????????SSS?B?BHHHHHHHB?BHHHHHHTT??TT?SS??HHHHHHTTTT?HHHHHHHHHHHS??SSB?S??EE??SS?SEEE?TTS?EEE?EEEEETTEEEEEEEE????SS???SS?EEEEEEEEEETTTTEEEEEEEEEEEEEESB?TT?S???EEEEEEEEEGGG??GGGEEEESSS??HHHHHHHHHHTTS?GGGB????EEEE??TT???EE????SS?S?????TT?EEEEEEEES?GGGHHHHHHHHHHH 1W9Z|A PF08979.6_DUF1894_seed 20 104 !Q:0,1|3,5|13,15|17,17|20,20|43,44|49,49|52,54|57,60|65,66|69,69|71,71|76,78|80,81|83,83|89,91|94,94 Q:2,2|6,12|16,16|18,19|21,42|45,48|50,51|55,56|61,64|67,68|70,70|72,75|79,79|82,82|84,88|92,93|95,103 ?-B???HHHHTTT???S?SS?EEESSHHHHHHHHTTSEEEEES??EEES-SS???SS????EEEE??TT-S?EEEE???S--S?EEEEE?--SS?GGGHHHHHH 1Z9V|A PF08980.5_DUF1883_seed 10 102 !Q:1,11|14,20|22,22|25,31|44,47|49,53|57,62|66,75|81,101 Q:0,0|12,13|21,21|23,24|32,43|48,48|54,56|63,65|76,80 S???????????TT???????S-SS???????HHHHHHHHHHTT???-S?????SSS??????SSS????????--TTSSS???????????????--???? 2B1Y|A PF08982.6_DUF1857_seed 17 183 !Q:0,0|7,19|33,33|38,38|40,40|42,44|52,60|71,79|101,103|117,123|140,143|145,155|179,182 Q:1,6|20,32|34,37|39,39|41,41|45,51|61,70|80,100|104,116|124,139|144,144|156,178 ?EEEEEE?????????????HHHHHHHHHHHHH?GGGT?T-T?-?EEEEEEE?--------SSEEEEEEEE---------TTEEEEEEEEEETTTEEEEEE???SSSBEEEEEEEEE-------EEETTEEEEEEEEEEE---?S?????????--BHHHHHHHHHHHHHHHHHHHHHH???? 2FFS|A PF08984.6_DUF1858_seed 33 61 !Q:13,13|24,25|27,27|43,43|54,55 Q:0,12|14,23|26,26|28,42|44,53|56,60 EETTSBHHHHHHH?GGGHHHHTTT--T?GGGGSHHHHTTHHHH?BHHHHHHHHT??HHHHH 2FI0|A PF08985.6_DUF1888_seed 4 126 !Q:0,5|18,18|28,28|32,32|35,35|37,37|41,41|46,46|54,54|58,59|75,75|80,80|91,93|95,95|106,106|109,109|112,112|115,118|123,125 Q:6,17|19,27|29,31|33,34|36,36|38,40|42,45|47,53|55,57|60,74|76,79|81,90|94,94|96,105|107,108|110,111|113,114|119,122 ??????EEEEEEEEEEEE-TTEEEEEEE?TTS?EE?S?EEE?SSEE-EEEEEEE?SSS??EEEEEEESSTTSSSS?EEEE?TTSSEEEEEE???S?EEEEEEEEEE?SS?SS?EE????EEEE??? 3NJL|A PF08986.5_DUF1889_seed 2 119 !Q:0,15|17,17|19,22|33,33|35,38|41,43|61,64|77,78|96,100|102,102|106,107 Q:16,16|18,18|23,32|34,34|39,40|44,60|65,76|79,95|101,101|103,105|108,118 ------------????S?S????HHHHHHHHHH?S????SS???STTHHHHHHHHHHHHHT????HHHHHHHHHHHT??HHHHHHHHHHHHHHHHT?????S?GGG??HHHHHHHHHHH 2JN8|A PF08987.5_DUF1892_seed 9 135 !Q:0,1|3,17|19,20|28,39|43,43|47,50|53,53|55,55|63,65|68,68|87,88|90,90|106,107|111,111|126,134 Q:2,2|18,18|21,27|40,42|44,46|51,52|54,54|56,62|66,67|69,86|89,89|91,105|108,110|112,125 ??S---------------S??EEEEEEE??-----?????TTT?SSS????SS?S?EEEEEEE???TT?HHHHHHHHHHHHHHHHTT??S?EEEEEETTTEEEEEE?-GGG-HHHHHHHHHHHHHH--------? 1N6Z|A PF08988.5_DUF1895_seed 5 69 !Q:0,0|10,12|38,39|65,68 Q:1,9|13,37|40,64 ?HHHHHHHHH---HHHHHHHHHHHHHHHHHHHHHHTTS??HHHHHHHHHHHHHHHHHHHHHHHHH???? 1ZW0|A PF08989.5_DUF1896_seed 7 147 !Q:0,0|22,22|28,28|51,52|68,68|70,71|89,89|103,103|114,116|119,119|145,147 Q:1,21|23,27|29,50|53,67|69,69|72,88|90,102|104,113|117,118|120,144 ?HHHHHHHHHHHHHHHHHHHHH?GGGTT?HHHHHHHHHHHHHHHHHHHHHT??HHHHHHHHHHHHHTT?S??HHHHHHHHHHHHSTTTS?TTHHHHHHHHHHT?HHHHHHHTTS???TT-GGGSTHHHHHHHHHHHHHHHHHHTT??- 2APL|A PF08990.6_Docking_seed 141 28 !Q:0,3|24,24 Q:4,23|25,27 ?-??HHHHHHHHHHHHHHHHHHHH-HHH 2HG4|A PF08991.5_DUF1903_seed 7 75 !Q:0,1|20,20|39,44|48,48|57,61|73,74 Q:2,19|21,38|45,47|49,56|62,72 ??TTHHHHHHHHHHHHHTTT?TTTTHHHHHHHHHHHTTS-----?GGG?HHHHHHHH-----HHHHHHHTTSS?? 2HP8|A PF08992.6_QH-AmDH_gamma_seed 9 78 !Q:0,2|6,9|12,12|16,16|25,25|46,47|52,52|59,59|69,72|74,77 Q:3,5|10,11|13,15|17,24|26,45|48,51|53,58|60,68|73,73 ???TTS????SS?SSS?TTSSSSSS?SSGGGGHHHHHTTTSSTTTS??TTTT?TTTTTT?SSHHHHGGG????S???? 1JJU|C PF08993.5_T4_Gp59_N_seed 8 99 !Q:0,1|19,19|21,22|29,34|41,41|43,43|54,55|70,70|74,76|80,80 Q:2,18|20,20|23,28|35,40|42,42|44,53|56,69|71,73|77,79|81,98 ??HHHHHHHHHHHHHHHTT-S??TTTTTT?-????HHHHHH?S?HHHHHHHHHH??HHHHHHHHHHHHHH?HHH---HSS?GGGTTHHHHHHHHHHHHH 1C1K|A PF08994.5_T4_Gp59_C_seed 10 109 !Q:16,16|25,25|32,32|44,44|56,56|64,64|66,68|74,74|89,89|92,94 Q:0,15|17,24|26,31|33,43|45,55|57,63|65,65|69,73|75,88|90,91|95,108 HHHHHHHHHHHHHHTT?SSGGGGTS?BTTTTB?HHHHHHHTTSS?HHHHHHHHHHH?HHHHHHH-H???HHHHH-HHHHHHHHHHHEEE?HH---HHHHHHHHHHHHHH 1C1K|A PF08995.5_NIP_1_seed 3 82 !Q:0,24|31,31|35,36|42,42|45,47|49,50|63,64|66,66|71,71|73,75|78,78|81,81 Q:25,30|32,34|37,41|43,44|48,48|51,62|65,65|67,70|72,72|76,77|79,80 ----------------------???EEEEEB?SSS??EEEEE?TT???B??EEEEETTEEEEE??B?TTSS?B???TT?EE? 1KG1|A PF08996.5_zf-DNA_Pol_seed 40 259 !Q:0,7|14,16|21,23|27,28|33,33|35,45|48,56|71,76|78,81|83,84|106,107|112,112|116,117|119,119|122,124|130,134|136,155|159,162|169,169|185,185|193,193|195,196|199,199|203,208|211,212|215,217|246,258 Q:8,13|17,20|24,26|29,32|34,34|46,47|57,70|77,77|82,82|85,105|108,111|113,115|118,118|120,121|125,129|135,135|156,158|163,168|170,184|186,192|194,194|197,198|200,202|209,210|213,214|218,245 ?????-??TTTTTT???EEEE?--TTT??EEEE?S-----------SS?-------?SSEEEETTEEEETT------T??--B??HHHHHHHHHHHHHHHHHHHHH??EEES?TTT??E-ES???SSTTB----?S--------------------STT?-??BEEESS?HHHHHHHHHHHHHHT?HHHHHTT?S??SS?TTS------TT??SS???HHHHHHHHHHTHHHHHHHHHHHHHHHTT?????????-??? 3FLO|B PF08997.5_UCR_6-4kD_seed 5 57 !Q:0,2|5,6|38,38|49,56 Q:3,4|7,37|39,48 ???TT-?SHHHHHHHHHSHHHHHHHHHHHHHHHHHHHT?HHHHTTSTTT???????? 1SQB|K PF08998.6_Epsilon_antitox_seed 3 89 !Q:0,2|32,33|36,36|55,55|59,60|82,88 Q:3,31|34,35|37,54|56,58|61,81 ???HHHHHHHHHHHHHHHHHHHHHHHHHHHTT??TT?TTSHHHHHHHHHHHHHTS?GGG??HHHHHHHHHHHHHHHHHHHHH??????? 3Q8X|A PF08999.5_SP_C-Propep_seed 3 94 !Q:0,90 Q:91,93 ????????????-?????????????--------------------------------?????????????????-???????????????EEE 2ESY|A PF09000.5_Cytotoxic_seed 5 94 !Q:1,5|9,10|13,13|16,17|21,24|26,26|31,31|33,34|42,45|66,66|73,73|77,78|80,80|82,84|87,87|89,89|93,93 Q:0,0|6,8|11,12|14,15|18,20|25,25|27,30|32,32|35,41|46,65|67,72|74,76|79,79|81,81|85,86|88,88|90,92 S?????GGG??SS?SE--EEE????B?SSSS?B??EEEETTT----TEEEEEETTTTEEEEEETTT?BEEEEE?TTT??B?S???TT?B?GGG? 1E44|B PF09001.6_DUF1890_seed 14 150 !Q:3,5|7,7|27,27|34,34|48,49|51,51|55,56|66,67|70,71|73,73|93,93|98,98|107,107|109,110|125,127|133,134|137,138 Q:0,2|6,6|8,26|28,33|35,47|50,50|52,54|57,65|68,69|72,72|74,92|94,97|99,106|108,108|111,124|128,132|135,136|139,149 EEE???S?STTHHHHHHHHHHHHHHTT?EEEEEE?HHHHHHHHHHSTT??S?SEE--EEHHHHHHH??TT--S?SEEEEEESSHHHHHHHHHH-HHHH?SEEEEEEE?S?-HHHHHHHHHHHHHH???EEEEE??SS??HHHHHHHHHHH 1KJN|A PF09002.6_DUF1887_seed 6 411 !Q:7,9|12,12|24,27|34,34|38,39|55,55|58,61|66,67|71,71|91,91|97,97|101,101|114,114|118,119|124,124|128,128|139,140|143,151|161,167|171,177|213,214|219,219|224,225|231,232|255,255|287,287|308,310|334,346|363,363|372,374|380,381|388,388|392,392 Q:0,6|10,11|13,23|28,33|35,37|40,54|56,57|62,65|68,70|72,90|92,96|98,100|102,113|115,117|120,123|125,127|129,138|141,142|152,160|168,170|178,212|215,218|220,223|226,230|233,254|256,286|288,307|311,333|347,362|364,371|375,379|382,387|389,391|393,410 TEEEEEE??-SS?HHHHHHHHSTT????EEEEEE?GGG--HHHHHHHHHHHHHTT?EE----EEEE??SSS?HHHHHHHHHHHHHHHHHHT?EEEEE?SSS?HHHHHHHHHHHH-HTT??EEEE?TTT?EEEEEESTTS??EE?-?????--HHHHHHHTT?------EEE???????HHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHH--HHHT?SEEE??HHHHT?-HHHHHHHHHHHHTTSEEEETTE-EEESSHHHHHHHHTTHHHHHHHHHHHHHHTT?TTEEEEEEEEEEEEEETTEE---EEEEEEEEEEETTEEEEEEEESS??????-----??HHHHHHHHHHHHHGGG?EEEEEESS???HHHHH--HHHHHT?EEE?GGGGGGHHHHHHHHHHTT 1XMX|A PF09003.5_Phage_integ_N_seed 17 78 !Q:0,13|19,19|22,26|28,28|33,33|37,38|42,43|45,46|65,69 Q:14,18|20,21|27,27|29,32|34,36|39,41|44,44|47,64|70,77 ????-?????????TTEEE?TT-----S?EEEE?TTT??EEE??S-?HHHHHHHHHHHHHHTTTS?????TTHHHHTT 1Z1G|A PF09005.5_DUF1897_seed 12 39 !Q:0,10|23,23|35,37 Q:11,22|24,34|38,38 -------????TTHHHHHHTTTT?HHHHHHHHHTT??-S 2BN6|A PF09006.6_Surfac_D-trimer_seed 10 46 !Q:0,1|46,46 Q:2,45 ??THHHHHHHHHHHHHHHHHHHHHHHHHHHTTTEEEETTEEEEEEE- 3G83|A PF09007.6_EBP50_C-term_seed 6 42 !Q:1,4|18,26|28,31|33,37|39,41 Q:0,0|5,17|27,27|32,32|38,38 S????HHHHHHTTGGGTT-????????S????S?????S??? 2KRG|A PF09008.5_Head_binding_seed 5 114 !Q:0,12|14,16|18,18|25,25|28,28|38,38|46,47|52,52|56,56|61,61|67,67|71,71|79,80|83,83|86,86|93,93|97,97|106,109 Q:13,13|17,17|19,24|26,27|29,37|39,45|48,51|53,55|57,60|62,66|68,70|72,78|81,82|84,85|87,92|94,96|98,105|110,113 -????????????S???B?SSSSSB?TT?EEEEESTTS?TTSGGGB??EEEE?TTS?EEEE?SSEEE?TTS?EEETTEE??EE?SS?EEEEEE?TTS?EEEEEEEE????HHHH 2VKY|B PF09009.5_Exotox-A_cataly_seed 2 236 !Q:5,8|14,14|20,20|29,30|55,55|65,71|74,75|82,82|99,100|102,103|108,110|116,118|136,136|139,139|143,143|146,147|156,156|159,160|162,162|172,173|179,179|186,186|195,197|200,205|211,211|217,227|230,235 Q:0,4|9,13|15,19|21,28|31,54|56,64|72,73|76,81|83,98|101,101|104,107|111,115|119,135|137,138|140,142|144,145|148,155|157,158|161,161|163,171|174,178|180,185|187,194|198,199|206,210|212,216|228,229 EEEEE????SGGGS?TTSSE-EETTEEES??HHHHHHHHHHHHHTTEEEEEEEEE?HHHHHHHHH???????TT??HHHHTT?SEEEBSSHHHHHTTSS??S??SGGG???HHHHS???EEEEEEEEGGGGGGEEE?SS?GGG?HH--HHHHHHTS?SS??S?EEEEESSTT??EEEEE?HHHHTT?EEEEEEEE???SS-?????HHHHH-HGGGG??????-----BS?????? 3NY6|A PF09010.5_AsiA_seed 6 101 !Q:0,10|32,32|50,50|53,53|58,59|71,71|82,82|84,84|98,100 Q:11,31|33,49|51,52|54,57|60,70|72,81|83,83|85,97 ?--------??HHHHHHHHHHHHHHHHHHTTH-HHHHSHHHHHHHHHHTT?EE-TTEE??HHHHHHHHHSS?HHHHHHHHHH?H-HHHHHHHHHHHHH??? 1TLH|A PF09011.5_HMG_box_2_seed 10 80 !Q:3,8|25,31|35,37|53,53|79,79 Q:0,2|9,24|32,34|38,52|54,78 SSS??????HHHHHHHHHHHHHHHH------?TTS???HHHHHHHHHHHHHSS?HHHHHHHHHHHHHHHHHHHHHHHHH? 2LY4|A PF09012.5_FeoC_seed 36 89 !Q:0,0|13,13|15,15|25,26|48,84 Q:1,12|14,14|16,24|27,47|85,88 ?HHHHHHHHHHHS?B?HHHHHHHTT??HHHHHHHHHHHHHHTSEEEEE???????---??????------??-----????????EEEE 4AWX|B PF09013.5_YopH_N_seed 4 122 !Q:0,1|11,11|21,21|33,33|36,37|40,41|46,47|64,67|83,85|101,101|105,107 Q:2,10|12,20|22,32|34,35|38,39|42,45|48,63|68,82|86,100|102,104|108,121 ??HHHHHHHHH-HHHTTTTSS?EEEESSSEEEE?SS??SS??SSSS??HHHHHHHHHHHHHHTT????HHHHHHHHHHHHHSS???EEEEEETTTEEEEEE?SSS???HHHHHHHHHHHHHH 1TTW|B PF09014.5_Sushi_2_seed 6 88 !Q:2,2|4,5|10,10|28,28|30,30|33,33|54,54|59,62|65,69|72,72|75,77|79,80|85,85|87,87 Q:0,1|3,3|6,9|11,27|29,29|31,32|34,53|55,58|63,64|70,71|73,74|78,78|81,84|86,86 EE?B??SSSS?EEEETTEEEEHHHHTTT?B?TT?EEEEEEEETTTTEEEEEEEE?BTTB????TT?????TT?TT---S??GGGS?B? 2KRI|A PF09015.5_NgoMIV_restric_seed 6 306 !Q:6,6|12,12|14,25|29,31|36,36|39,39|55,58|60,69|97,97|105,106|110,110|112,113|133,133|141,148|156,156|158,158|164,164|168,173|178,178|180,180|182,182|186,186|188,191|193,197|209,210|228,228|232,233|240,243|257,257|277,277|305,305 Q:0,5|7,11|13,13|26,28|32,35|37,38|40,54|59,59|70,96|98,104|107,109|111,111|114,132|134,140|149,155|157,157|159,163|165,167|174,177|179,179|181,181|183,185|187,187|192,192|198,208|211,227|229,231|234,239|244,256|258,276|278,304 HHHHHH-HTTSS?B?-----------TTS--?BTTS?TT?HHHHHHHHHHHHHTT?-??B????-----?HHHHHHHHHHHHHHHHHHHHGGGTTTS?SEEEEEE??SSS?S?-GGGSGGGTHHHHHHHHHHH?HHHHHHH????????SEEEEEE?B?HHHHT-SSS????--TTSS?S?T-TBS?S----S???--EEEEEEEEESS??TTGGGHHHHHHHHHHHH?SSS??EEEEEE????HHHHHHHHSSSSS?SEEEETTHHHHHHHHHHTT?HHHHHHHHHHHHTTSEEEGGGHHHHTT? 4ABT|A PF09016.5_Pas_Saposin_seed 6 76 !Q:15,15|31,33|53,54|71,75 Q:0,14|16,30|34,52|55,70 HHHHHHHHHHHHHHS?GGGHHHHHHHHHHHH???HHHHHHHHHHTHHHHHHTS??SHHHHHHHHHHHHHHH??--- 2B8I|A PF09017.5_Transglut_prok_seed 4 424 !Q:0,43|50,51|64,104|108,111|113,114|136,136|141,145|167,171|175,176|178,178|189,192|195,196|210,210|232,233|251,251|256,257|269,269|281,281|295,295|297,299|303,303|310,311|316,318|322,322|325,326|329,336|342,344|346,346|353,356|358,358|362,362|370,371|380,380|393,394|397,397|411,412|415,415|417,419|423,423 Q:44,49|52,63|105,107|112,112|115,135|137,140|146,166|172,174|177,177|179,188|193,194|197,209|211,231|234,250|252,255|258,268|270,280|282,294|296,296|300,302|304,309|312,315|319,321|323,324|327,328|337,341|345,345|347,352|357,357|359,361|363,369|372,379|381,392|395,396|398,410|413,414|416,416|420,422 ----------------------------------??????????HHHHHT??HHHHHHHHHHHH?????????-------??----??????---??????????TTS????B??BTTEEEEEHHHHHHHHHHTTT?BTTB?????HHHHHHHTTSHHHHHHHHHTS?????SEE??B?HHHHHHHHHH????TT??HHHHHHHHHHHTB?HHHHHHHHHHHHHHHHHHHTT??SHHHHHHHHHHHHHHTT?GGGG??TTSHHHHTTTT?HHHHSTTTTTT?GGGEEEEEEEEEE?S???TTS?HHHHHH??TTSS???TTT?EE??TT????????SBTTB???S?EEEEEE????S?GGG?EEEEESS??BTTSSSBS?EEEEEEHHHHHT??TT?SEEEEEEEEEETT??SS?S???SSB? 1IU4|A PF09018.6_Phage_Capsid_P3_seed 3 394 !Q:0,14|46,46|50,51|56,60|77,78|81,82|86,86|101,101|105,105|129,130|132,132|134,135|138,139|144,144|148,149|153,153|156,156|174,175|178,178|183,184|187,188|195,196|203,203|207,208|211,211|238,239|246,248|264,267|271,271|276,277|280,280|295,296|312,312|315,316|318,318|334,334|343,343|347,347|349,349|355,355|364,366|381,393 Q:15,45|47,49|52,55|61,76|79,80|83,85|87,100|102,104|106,128|131,131|133,133|136,137|140,143|145,147|150,152|154,155|157,173|176,177|179,182|185,186|189,194|197,202|204,206|209,210|212,237|240,245|249,263|268,270|272,275|278,279|281,294|297,311|313,314|317,317|319,333|335,342|344,346|348,348|350,354|356,363|367,380 ???????????????HHHHHHHHHHHHHHHHHHSEEEEEEEEEEEE?TTT??EEEE?????SEEEEEEEEEEEEEEE??SS??EEE?SSGGGGSEEEEEEE?TTS?EEEEEEHHHHHHHHHHHHTSSTT??B?B??SS??BSSS?SSB??SEE?TT?EEEEEEEEEEESSSSSS??TT?EETT??SS??EEEEEE??TTTSEE?TTS??TT?SEESTTGGGEEEEEEEEEEEEEEEES??EETTEE???HHHHTEEEEEEEEEE????TTS?EEEE??SS?EEEEEEEEEEETTB??SSTTEEEEEEEESSS?BS??B?HHHHHHHHHHHHSSB?STTEEEEE?SSS?B?HHHHS?EEEEEEES???TTEEEEEEEEEEEE????????????? 1CJD|A PF09019.6_EcoRII-C_seed 14 199 !Q:15,16|18,23|30,37|68,75|77,97|100,100|105,120|122,123|129,129|132,132|138,149|153,154|156,159|171,172|175,176|184,184|191,193 Q:0,14|17,17|24,29|38,67|76,76|98,99|101,104|121,121|124,128|130,131|133,137|150,152|155,155|160,170|173,174|177,183|185,190|194,198 HHHHHHHHHHHHHHH??S------SHHHHH--------HHHHHHHHHHHHHSSSHHHHHHHHHHHTSS?---????S??---??-----?????????BS?GGGG?------?????????B??EEESS?TT?SGGGG?????--?????EEE??S?-??HHHHHHHHTTT??EE??HHHHTTS?TTTGGG???HHHHH 1NA6|A PF09020.5_YopE_N_seed 2 126 !Q:0,21|34,36|45,53|58,58|62,62|65,66|77,125 Q:22,33|37,44|54,57|59,61|63,64|67,76 ----------------??????TTEETTEEEEEE???HHHHHHHT?????????STTS?EEE?SS??HHHHHHHHHH????????----------------------------------------- 1L2W|I PF09021.6_HutP_seed 17 147 !Q:0,0|11,14|17,18|24,25|30,30|41,46|65,65|90,92|98,98|110,111|118,119|131,131|136,136|147,147 Q:1,10|15,16|19,23|26,29|31,40|47,64|66,89|93,97|99,109|112,117|120,130|132,135|137,146 ?HHHHHHHHHT?-??TT??HHHHH--HHTT?EEEEEEEEES-----?HHHHHHHHHHHHHHTTSS?SSSSHHHHHHHHHHHHHHHHHHTT???SGGGT?EEEEEEEEEEE??BSSGGG??EEEEEEEEEEE?SSTT?EEEEEEEEEE- 1WPV|A PF09022.5_Staphostatin_A_seed 3 105 !Q:0,1|3,3|9,13|16,17|36,37|44,44|48,49|71,71|78,79|83,83|94,94|98,99|103,103 Q:2,2|4,8|14,15|18,35|38,43|45,47|50,70|72,77|80,82|84,93|95,97|100,102|104,104 ??S?EEEEE?????SS??HHHHHHTBEEESSSTTTT??EEEEES?TTT??EEEEEEETTTTEEEEEETTTS?EEEEEE??SSS?EEEEEEETTS?BSS??EEE?S 1OH1|A PF09023.5_Staphostatin_B_seed 2 107 !Q:0,1|10,11|16,16|27,27|44,45|48,48|97,97|99,101 Q:2,9|12,15|17,26|28,43|46,47|49,96|98,98|102,106 ??EEEEEEEE??GGGS?HHHHHHHHTT?EEEEETTTTEEEEEEE??TT?SSEEEEEEEETTTTEEEEEETTEEEEEEEEEEEETTEEEEEEEESSSB?B???EEEEE 1Y4H|C PF09025.5_YopR_core_seed 9 156 !Q:0,26|40,44|46,46|49,50|72,73|75,77|94,94|110,121|136,155 Q:27,39|45,45|47,48|51,71|74,74|78,93|95,109|122,135 ----------------------?????HHHHHHHHHHHHH-----H?SS??HHHHHHHHHHHHHHHHHHHTT??S???HHHHHHHHHHHHHHHS?SSHHHHHHHHHHHHT??????--????HHHHHHHHHHHHHH?????--------------- 1Z21|A PF09026.5_CENP-B_dimeris_seed 2 101 !Q:0,44|63,65|86,100 Q:45,62|66,85 -------------------------------------????????HHHHHHHHHHHHHHHTTS???HHHHHHHHHHHHHHHHHHHH??????????????? 1UFI|A PF09027.5_GTPase_binding_seed 5 71 !Q:0,1|7,9|11,11|14,25|28,31|34,37|41,70 Q:2,6|10,10|12,13|26,27|32,33|38,40 ??SSSTT???S?SS????????????SS?-??SS????TTT??---------------------------- 1CF4|B PF09028.5_Mac-1_seed 3 387 !Q:0,52|54,73|76,76|79,82|84,85|88,88|91,100|104,106|111,118|122,123|127,127|155,155|167,168|181,181|185,188|207,210|221,225|228,229|231,242|245,246|253,253|256,256|260,261|267,267|270,271|287,287|294,297|303,303|314,314|318,318|326,326|329,329|331,331|335,335|344,344|348,348|355,356|358,365|369,370|380,382 Q:53,53|74,75|77,78|83,83|86,87|89,90|101,103|107,110|119,121|124,126|128,154|156,166|169,180|182,184|189,206|211,220|226,227|230,230|243,244|247,252|254,255|257,259|262,266|268,269|272,286|288,293|298,302|304,313|315,317|319,325|327,328|330,330|332,334|336,343|345,347|349,354|357,357|366,368|371,379|383,386 -----------------?-----------?????????----???????????E--------------------EE?TT????S??EE?SS?---------EEE???SSSS????????SSS--STT?HHHHHHHHHHHHHHHHTHHHHHHHHHH?GGGSEEEETEE--EEEHHHHHHHTT?TTT---?HHHHHHHHTTSSGGGGTT????HHHHHHHHHT?????SS??S?????????--?TT??TTTTTS?SS?GGG??EEEEE?TT??HHHHHHHHHHHHHTT?EEEEEE--??SSTTS?EEEEEEEEEE?TTS?EEEEEEE?TT-S?TTT?EEEEEEEE?TTS?EEEESS??B--------TTB??EEEEEEEEE???HHHH 2AVW|A PF09029.5_Preseq_ALAS_seed 2 113 !Q:0,2|5,5|7,8|10,13|16,16|18,18|21,21|34,34|37,38|40,51|53,53|55,55|57,57|59,112 Q:3,4|6,6|9,9|14,15|17,17|19,20|22,33|35,36|39,39|52,52|54,54|56,56|58,58 ???SS?S??S????SS?S?SS?TTTTTHHHHHSS?SS??S------------S?S?S?S??---------------------------------------------------- 1H7J|A PF09030.5_Creb_binding_seed 4 112 !Q:0,53|55,59|73,73|89,89|109,111 Q:54,54|60,72|74,88|90,108 ---------------------------??-------------------------S??--?TTHHHHHHHHHTS?SSSHHHHHHHHHHHH?HHHHHHHHHHHHTTTTTTS??? 2C52|A PF09032.6_Siah-Interact_N_seed 10 81 !Q:0,0|47,50|55,80 Q:1,46|51,54 ?HHHHHHHHHHHHHHHHHHHHTTTTTHHHHHHHHHHHHHHHHHHHHH----SSTT????????-????????????????? 1YSM|A PF09034.5_TRADD_N_seed 6 114 !Q:3,5|9,10|27,29|59,61|63,66|75,76|83,83|95,98|101,101 Q:0,2|6,8|11,26|30,58|62,62|67,74|77,82|84,94|99,100|102,113 HHT-??TTT??EEEEEEETTEEEEEEE???HHHHHHHHHHHHHHHHHHHHHHHHHHHHT?--S????EEEEESSS??HHHHHH?HHHHHHHHHHS????SS?HHHHHHHHHHHH 1F2H|A PF09035.5_Tn916-Xis_seed 8 69 !Q:0,8|25,25|27,27|38,38|41,41|65,68 Q:9,24|26,26|28,37|39,40|42,64 ?????--??TTTSSEEEHHHHHHHT?S?HHHHHHHHHH?TT?SSEEEETTEEEEESHHHHHTSTT???? 1Y6U|A PF09036.5_Bcr-Abl_Oligo_seed 4 89 !Q:0,2|14,14|17,18|20,26|32,39|76,88 Q:3,13|15,16|19,19|27,31|40,75 ???HHHHHHHHHHH?TT--S???????SSHHH--------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??????------- 1K1F|A PF09037.5_Sulphotransf_seed 13 278 !Q:6,6|25,29|32,35|41,44|50,54|62,73|87,87|91,91|111,112|115,117|130,130|132,133|138,138|140,142|157,193|220,222|224,225|248,248|251,270|275,277 Q:0,5|7,24|30,31|36,40|45,49|55,61|74,86|88,90|92,110|113,114|118,129|131,131|134,137|139,139|143,156|194,219|223,223|226,247|249,250|271,274 EEEEEE?TTSTHHHHHHHHHHHTSS?????TT??-?TTTSS???-HHHHT?????TTTTTTS????????????HHHHHHHHHHHTB?TTS?EEEEEEGGGHHHHHHHHTT?-TT???SSHHHHHHHHHT-S??EEEE?B???HHHHHHHHHHHHHH????--??????????-----------------????HHHHHHHHHHHHHHHHHHHHHHHHTT???B??BHHHHHHHHHHHHHHHHHHTTS?TT???--???????????????STTT??? 1TEX|A PF09038.5_53-BP1_Tudor_seed 3 122 !Q:0,2|6,6|11,11|14,14|26,27|36,36|40,40|53,54|56,56|66,66|70,70|99,99|120,120 Q:3,5|7,10|12,13|15,25|28,35|37,39|41,52|55,55|57,65|67,69|71,98|100,119|121,121 ???STT?EEEE?SS?SSEEEEEEEEE??TTTEEEEE?TTS?EEEEETTTEEEE??S?SSEEEEESS?TTT?EEEEEEEEEEETTEEEEEEEETTEEEEE?GGGEEEEHHHHHTTTTTTSS?S 3LH0|A PF09039.6_HTH_Tnp_Mu_2_seed 6 113 !Q:7,7|16,35|51,53|70,75|84,84|88,88|97,98|103,112 Q:0,6|8,15|36,50|54,69|76,83|85,87|89,96|99,102 HHHHHTS?GGGHHHHH????---?????????????HHHHHHHHHHHTSTT???HHHHHHHHHHHHHHHT?-????HHHHHHHH-HHH?HHHHHHHH??HHHH?????????? 2EZH|A PF09040.6_H-K_ATPase_N_seed 5 42 !Q:0,41 Q: ??????????????????????????-??????????????? 2YN9|A PF09041.5_Aurora-A_bind_seed 6 68 !Q:0,9|12,13|15,18|20,30|40,67 Q:10,11|14,14|19,19|31,39 ??????????SS??B????S???????????TTHHHHHHS???------------------------- 1OL5|B PF09043.6_Lys-AminoMut_A_seed 8 510 !Q:1,3|43,44|47,47|51,51|66,66|70,70|83,85|97,99|104,107|141,144|147,147|154,155|157,157|173,173|179,181|187,187|190,192|194,195|197,198|202,205|226,227|233,234|250,250|255,256|265,265|267,267|287,287|291,292|301,301|325,326|332,332|336,337|339,339|364,365|369,371|374,375|377,377|397,397|402,404|412,413|438,441|481,484|487,487|497,498|501,503 Q:0,0|4,42|45,46|48,50|52,65|67,69|71,82|86,96|100,103|108,140|145,146|148,153|156,156|158,172|174,178|182,186|188,189|193,193|196,196|199,201|206,225|228,232|235,249|251,254|257,264|266,266|268,286|288,290|293,300|302,324|327,331|333,335|338,338|340,363|366,368|372,373|376,376|378,396|398,401|405,411|414,437|442,480|485,486|488,496|499,500|504,509 S???HHHHHHHHHHHHHHHHHHHHHHHTEEEHHHHHHHHHHTT??SB?TTS?BHHHHHHHHHHHTT?TTT?HHHHHHHHHHTT???HHHHHHHHHHT???TTTS????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-???SS?EEEEEE??S?HHHHHHHHHHHHHTT?SEEEE???TTGGG?SS???S??S??TTS????HHHHHHHHHHHHHHHHHHTS??EEEEE??STTHHHHHHHHHHHT?SEEE??SSHHHHHH?B?HHHHHHHHHHHHHHHHHTT?EEE??THHHHSSS?TTTSHHHHHHHHHHHHHHHHHTT??GGGEE?EEE??S?TTSTTHHHHHHHHHHHHHHHSTTS??EEE???TT??S?HHHHHHHHHHHHHHHHHHT?SEEE???TTTTTSS??HHHHHHHHHHHHHHHHHTTTHHHH????TTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTT????TT?SBTGGGEEE??TT???HHHHHH 3KOW|A PF09044.5_Kp4_seed 2 131 !Q:0,15|18,21|25,26|30,30|32,32|40,40|45,45|51,51|54,56|61,66|69,69|78,78|81,82|100,100|103,103|108,110|115,116|120,120|128,128|130,130 Q:16,17|22,24|27,29|31,31|33,39|41,44|46,50|52,53|57,60|67,68|70,77|79,80|83,99|101,102|104,107|111,114|117,119|121,127|129,129 --------------??SB????HHH--HHS?S?HHHHHHH-HHHH?TTSEE?BT???EEEE-----?SS?EEEEEEES-SS??EEHHHHHHHHHHHHHHT?SS?EEEE---SSTT??GGG?EEEEEEE-S? 1KPT|A PF09045.5_L27_2_seed 3 58 !Q:20,21|36,36|56,57 Q:0,19|22,35|37,55 HHHHHHHHHHHHHHHHHHHT??STHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHHH?? 1Y76|A PF09046.5_AvrPtoB-E3_ubiq_seed 4 126 !Q:0,11|25,47|49,49|55,56|59,59|62,63|71,73|77,85|102,102|104,104|108,109|111,111|125,125 Q:12,24|48,48|50,54|57,58|60,61|64,70|74,76|86,101|103,103|105,107|110,110|112,124 ???-----????TTGGGGGGSEEEE???????????????????????B?TTSSB??TT?TT??EEEEESS???TTS?????????EEEEEHHHHHHHHHHS?B?TTT??B?STTTHHHHEEEEE? 2FD4|A PF09047.5_MEF2_binding_seed 2 35 !Q:0,4|7,9|24,24|28,34 Q:5,6|10,23|25,27 ?????SS???HHHHHHHHHHHHTT?STT??????? 1N6J|G PF09048.5_Cro_seed 5 61 !Q:0,2|24,26|38,39 Q:3,23|27,37|40,60 ??-EEEEHHHHHHHTTHHHHHHHH???HHHHHHHHHHT??EEEEEETTTEEEEEEEEESSS 1COP|D PF09049.5_SNN_transmemb_seed 3 33 !Q:0,0|3,3 Q:1,2|4,32 ?SS?TTTTHHHHHHHHHHHHHHHHHHHHHHHHH 1ZZA|A PF09050.5_SNN_linker_seed 3 26 !Q:5,5|8,8|11,13 Q:0,4|6,7|9,10|14,25 TTTSS?SS?SS???TTTTTTTSSSTT 1ZZA|A PF09051.5_SNN_cytoplasm_seed 5 27 !Q:20,22|26,26 Q:0,19|23,25 HHHHHHHHHHHHHHHHHHHS???TTT? 1ZZA|A PF09052.5_SipA_seed 3 713 !Q:0,24|39,52|71,71|82,84|108,108|130,132|135,135|142,143|165,171|193,193|197,197|199,199|206,206|228,239|260,712 Q:25,38|53,70|72,81|85,107|109,129|133,134|136,141|144,164|172,192|194,196|198,198|200,205|207,227|240,259 ----------------------???HHHHTEEEEEEESS??????????????HHHHHHHHHHHHHHTTSS?HHHHHHHHHH???HHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHH???SS?SSSTTS??SHHHHHHHHHHHHHHHHHHHH???????HHHHHHHHHHHHHHHHHHHHH?SSS?S?HHHHTT?HHHHHHHHHHHHHHHHHHHHH????????????HHHHHHHHHHHHHHHHHHHH?----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1Q5Z|A PF09053.5_CagZ_seed 3 199 !Q:0,0|2,2|4,5|41,42|63,64|94,96|131,131|135,136|139,140|176,198 Q:1,1|3,3|6,40|43,62|65,93|97,130|132,134|137,138|141,175 -T?S??HHHHHHHHHHTTTTTTTHHHHHHHHHHHHTGGGGG??SHHHHHHHHHHHHHHHHHTT??SHHHHHHHHHHHHHHHHHHHHHHHHHHHH???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS?GGG??TT??HHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHH??????????????????????? 1S2X|A PF09055.6_Sod_Ni_seed 25 160 !Q:0,23|33,37|49,51|53,66|95,96|102,111|113,113|131,132|135,137 Q:24,32|38,48|52,52|67,94|97,101|112,112|114,130|133,134|138,159 --------------??????????THHHHHHHH-----HHHHHHHHHHH???H--------------HHHHHHHHHHHHHHHHHHHHHHHHHHTT??HHHHH----------H?TTHHHHHHHHHHHHHHH--HH???HHHHHHHHHHHHHHHHHHHHHT 1Q0K|A PF09056.6_Phospholip_A2_3_seed 18 133 !Q:8,8|20,21|26,26|28,34|40,47|53,58|77,79|86,87|101,103|106,107|110,110 Q:0,7|9,19|22,25|27,27|35,39|48,52|59,76|80,85|88,100|104,105|108,109|111,132 HHHHHHSS?HHHHHHHHHTT--SSTT-S--?????TTTTS?-------SSGGG?---??HHHHHHHHHHHHHHHHTT???HHHHHH--HHHHHHHHHHHHH---TT??SS?TTHHHHHHHHHHHHHHHHHHHT 1LWB|A PF09057.5_Smac_DIABLO_seed 4 247 !Q:0,62|171,171|217,228|246,247 Q:63,170|172,216|229,245 ---------------------------------------------------????????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH------------HHHHHHHHHHHHHHHTT?- 1G73|A PF09058.5_L27_1_seed 4 65 !Q:0,3|21,22|26,26|57,58|62,63 Q:4,20|23,25|27,56|59,61|64,64 -???HHHHHHHHHHHHHHHHT??SSS?TTHHHHHHHHHHHHHSHHHHHHHHHHHHTT??TTT-?G 1RSO|A PF09059.5_TyeA_seed 7 87 !Q:0,3|20,21|33,34|55,55|61,61 Q:4,19|22,32|35,54|56,60|62,86 ????HHHHHHHHHHHHHSTT??HHHHHHHHHTT??SSHHHHHHHHHHHHHHHHTS?GGGSS?HHHHHHHHHHHHHHHHHHHHHHHHH 1XL3|C PF09060.5_L27_N_seed 4 49 !Q:15,16|33,33|47,48 Q:0,14|17,32|34,46 HHHHHHHHHHHHHTT??SHHHHHHHHHHHHHHH?HHHHHHHHHHHHH?? 1Y76|B PF09061.1_Stirrup_seed 3 79 !Q:0,2|5,7|20,20|40,40|48,48|66,67 Q:3,4|8,19|21,39|41,47|49,65|68,78 ???EE???HHHHHHHHHTTT?EEEEETTEEEEEETTEEEE?TTHHHHS?EEHHHHHHHHHHHHHHH??HHHHHHHHHHH 1DQ3|A PF09062.5_Endonuc_subdom_seed 3 98 !Q:0,8|28,29|34,35|46,46|63,67|73,73|79,80 Q:9,27|30,33|36,45|47,62|68,72|74,78|81,97 ?????????HHHHHHHHHHHHEEEEEEE??BTTB??EEEEEEEEES?HHHHHHHHHHHHHHHS?????EESSS?EEEEE??HHHHHHHHHHHTTGGGS 1DQ3|A PF09063.5_Phage_coat_seed 2 127 !Q:0,1|19,20|23,24|28,30|32,32|36,37|45,46|65,66|73,75|93,94|111,111|121,123|125,126 Q:2,18|21,22|25,27|31,31|33,35|38,44|47,64|67,72|76,92|95,110|112,120|124,124 ??EEEEEETTEEEEEEEEE??SS??EEE???S?SSS??EEEEEEE??TTTTEEEEEEEEEEEEEE??TTTSTT???EEEEEEEEEEEEEEETT??HHHHHHHHHHHHHHHT?HHHHHHHHH???S?? 2QUD|A PF09064.5_Tme5_EGF_like_seed 6 39 !Q:0,0|7,9|11,12|16,19|23,23|27,30|34,38 Q:1,6|10,10|13,15|20,22|24,26|31,33 ?STTSSS???S??TTT??--TTT?SSS????TTT---?? 3GIS|X PF09065.5_Haemadin_seed 2 27 !Q:2,2|8,8|11,12|17,17|19,19|21,26 Q:0,1|3,7|9,10|13,16|18,18|20,20 EE?SSSEE?TT??BSSS?B?S?????? 1E0F|I PF09066.5_B2-adapt-app_C_seed 31 123 !Q:0,1|4,10|22,23|27,28|36,37|39,42|55,55|66,68|77,77|81,81|90,90|93,95|106,107 Q:2,3|11,21|24,26|29,35|38,38|43,54|56,65|69,76|78,80|82,89|91,92|96,105|108,122 ??TT---????HHHHHHHHHHS-?GGG--EEEEEET--T????HHHHHHHHHHTT?EEEEEEESSS--?EEEEEEEE?TTS?EEEEEEEE?SS???EEEEEEESST--TSHHHHHHHHHHHTT 3HS9|A PF09067.5_EpoR_lig-bind_seed 12 109 !Q:4,4|7,10|12,14|23,24|31,33|36,37|50,50|57,58|63,63|67,67|69,69|75,76|79,79|81,82|86,86|92,92|98,98|106,106 Q:0,3|5,6|11,11|15,22|25,30|34,35|38,49|51,56|59,62|64,66|68,68|70,74|77,78|80,80|83,85|87,91|93,97|99,105|107,108 HHHH-HH????S???EEEBSSTT??EEEEEE???TT??GGGEEEEEEETT-EEEEEE??EEEE?TTS?E-EEEEE??GG-G??SSS?EEEEE-EETTS?EEEEEEE?GG 1F6F|B PF09068.6_EF-hand_2_seed 30 327 !Q:9,10|16,16|36,44|48,49|62,64|66,79|83,87|102,152|163,165|168,291|306,306|309,310 Q:0,8|11,15|17,35|45,47|50,61|65,65|80,82|88,101|153,162|166,167|292,305|307,308|311,326 HHHHHHHHG--GGGTT?SSHHHHHHHHHHHHHHHTT---------GGG??HHHHHHHHHHTT???T--------------TSE-----EEHHHHHHHHHHHH---------------------------------------------------HHHHHHSSSS?-?HH----------------------------------------------------------------------------------------------------------------------------HHHHHHHHHHHHHH?TT??SEEEHHHHHHHHHHTS 1EG4|A PF09069.6_EF-hand_3_seed 30 133 !Q:12,18|20,20|24,24|26,26|46,46|52,52|54,56|68,71|73,94|96,96|98,98|100,100|102,106|116,119 Q:0,11|19,19|21,23|25,25|27,45|47,51|53,53|57,67|72,72|95,95|97,97|99,99|101,101|107,115|120,132 HHHHHHHHHHHH-------S?TTS?B?HHHHHHHHHHHHHHHHHTT?GGGGT?S-??HHHHHHHHHHT----T----------------------T?S?B?H-----HHHHHHHHT?--?TTTTHHHHHHHHH 1EG4|A PF09070.6_PFU_seed 39 133 !Q:0,60|75,76|81,82|88,88|92,92|106,109|124,132 Q:61,74|77,80|83,87|89,91|93,105|110,123 ?????????????????-?????????--???????????????----??-?------???EEETTEEESEEEEE??STTS??EEEEE?TTS?HHHHHHHHHHHHT--??GGGHHHHHHHHHHH--??????? 2K8C|B PF09071.5_Alpha-amyl_C_seed 5 68 !Q:1,4|9,9|17,17|20,20|34,36|46,46|48,48|52,52|56,56|60,60|67,67 Q:0,0|5,8|10,16|18,19|21,33|37,45|47,47|49,51|53,55|57,59|61,66 T????EEEE?SSEEEEE?SS?EEEEESSSEEEEE???EEEEEESSS?S?SEE?SEE-EEE?SEEEEE? 3VGH|A PF09075.5_STb_secrete_seed 2 48 !Q:0,2|6,6|23,23|32,33|47,47 Q:3,5|7,22|24,31|34,46 ???STT?SSHHHHHHHHHHHHHS?SSSSSSSS??TTTTTHHHHTTTT? 1EHS|A PF09076.5_Crystall_2_seed 10 77 !Q:5,5|8,8|15,15|19,20|22,29|31,32|38,38|42,43|55,56|59,59|62,63|67,71|73,74|76,76 Q:0,4|6,7|9,14|16,18|21,21|30,30|33,37|39,41|44,54|57,58|60,61|64,66|72,72|75,75 EEEEE?SS?EEEEEE?SSB??B??------S??EEEEE?TTS??EEEETTTEEEE??SS?EE??SSS?????B??B? 1F53|A PF09077.6_Phage-MuB_C_seed 15 82 !Q:0,4|7,8|11,11|26,27|43,44|46,46|59,59|62,62|66,68 Q:5,6|9,10|12,25|28,42|45,45|47,58|60,61|63,65|69,81 ?????TT??SS?SGGGTTHHHHSSTT--SSSHHHHHHHTTSSS-?S?HHHHHHHHGGGT?TT?TTS??-SSHHHHHHHHTSS 1F6V|A PF09078.6_CheY-binding_seed 30 65 !Q:0,0|5,5|7,8|24,25|31,31|34,34|39,42|44,44|57,57 Q:1,4|6,6|9,23|26,30|32,33|35,38|43,43|45,56|58,64 ?EEEE?S??TTHHHHHHHHHHHHS??EEEEE?SS?EEEE????S?HHHHHHHHTTTS?TTSEEEE 1EAY|C PF09079.6_Cdc6_C_seed 83 101 !Q:11,16|33,33|36,42|44,44|67,67|69,70|72,72|74,74|80,81|84,84|86,87|95,99 Q:0,10|17,32|34,35|43,43|45,66|68,68|71,71|73,73|75,79|82,83|85,85|88,94|100,100 HHHHHHHSSSS?----?EEHHHHHHHHHHHHHH-TT?--????H-HHHHHHHHHHHHTTSEEEEEEE?G--G-G?EEEEE--EE?S?-HHHHHHH-----H 1FNN|A PF09080.5_K-cyclin_vir_C_seed 2 107 !Q:0,2|16,16|45,45|58,59|64,71|82,83|101,106 Q:3,15|17,44|46,57|60,63|72,81|84,100 ???HHHHHHHHHHHHS?SSTTHHHHHHHHHHHHHHHHTSTTGGGS?HHHHHHHHHHHH??GGGS????????HHHHHHHHHT??HHHHHHHHHHHHHHHHH???-?? 1G3N|C PF09081.5_DUF1921_seed 5 51 !Q:11,11|14,14|22,26|31,32|34,35 Q:0,10|12,13|15,21|27,30|33,33|36,50 TTSSSEEEEEE?SS?EEEEEES?????GGGT??S??EEEEEETTTTEEEEE 1QI5|A PF09082.5_DUF1922_seed 3 70 !Q:9,10|17,17|30,31|35,35|38,39|55,57|59,59|64,64|68,69 Q:0,8|11,16|18,29|32,34|36,37|40,54|58,58|60,63|65,67 EEEEEETTS??EEEETT?SEEEETTTEEEE??SSS?BS??SSHHHHHHHHHHHSS???S?TTSS?TTS?? 1GH9|A PF09083.5_DUF1923_seed 2 64 !Q:5,6|28,28|32,32|54,54|57,57|63,63 Q:0,4|7,27|29,31|33,53|55,56|58,62 SEEEE??BTTEEEEEEEETTEEEEEEEE?SSS?EEEEEEEEESSSEEEEEEEEE?TT?EEEEE? 1GJU|A PF09084.6_NMT1_seed 60 250 !Q:0,0|20,21|23,23|29,29|31,31|45,45|47,47|57,58|63,63|66,67|76,79|90,91|93,94|102,102|106,107|111,112|115,116|130,133|142,143|150,150|162,162|172,173|183,184|190,192|194,204|206,206|210,210|223,224|245,245 Q:1,19|22,22|24,28|30,30|32,44|46,46|48,56|59,62|64,65|68,75|80,89|92,92|95,101|103,105|108,110|113,114|117,129|134,141|144,149|151,161|163,171|174,182|185,189|193,193|205,205|207,209|211,222|225,244|246,249 ?GGGHHHHHHHHTTTTGGGT??E-EEEEE-S?GGGHHHHHHTTSS?E-EEEEHHHHH--HHHH-TT??EEEEEEEE????EEEEEETTSS??S--SGGGGTT?EEE--ESS--SH--HHHHHHHHTGGGT?--?TTSSEEEE?-GGGHHH-HHHTTSSSEEE-EETTTHHHH--HHHHHHHTT??GGGEE---E???????????G-GGG?EEEEEEHHHHHH-?HHHHHHHHHHHHHHHHHHHH?HHHH 2Q2C|A PF09085.5_Adhes-Ig_like_seed 5 114 !Q:1,2|4,4|13,13|15,17|29,30|35,35|46,46|49,56|61,62|66,68|80,84|87,88|113,113 Q:0,0|3,3|5,12|14,14|18,28|31,34|36,45|47,48|57,60|63,65|69,79|85,86|89,112 B??S?EEEESSSB?S?-?SEEEEEEEEEB??STTS?EEEEEETTEE?TT????????EEEE??SSS??-EEEEEEEEEEE?????SS??SEEEEEEEEEETTEEEEEEEEEEB? 1BQS|A PF09086.6_DUF1924_seed 17 101 !Q:6,6|8,10|20,22|26,26|28,28|30,31|38,38|44,44|47,48|52,52|55,56|67,68|87,89 Q:0,5|7,7|11,19|23,25|27,27|29,29|32,37|39,43|45,46|49,51|53,54|57,66|69,86|90,100 HHHHHT-S???HHHHHHHHH???SSS?T-T??STHHHH?SSTTS?EE-?TTS?EE??SSTTTSTTTT??HHHHHHHHHHHHHHHHSS???HHHHHHHHHHH 1DW0|A PF09087.6_Cyc-maltodext_N_seed 28 106 !Q:5,5|10,10|13,13|21,21|27,30|36,38|49,50|63,63|66,67|79,90|102,104 Q:0,4|6,9|11,12|14,20|22,26|31,35|39,48|51,62|64,65|68,78|91,101|105,105 EEESS?EESS?SS?EEEEEEE?TTGGG----SEEEE??-TTEEEEEEEE-?SSTTEEEEEEEE?TT??SEEEEEEEEET------------TEEEEEEEEEE???T 3EDD|A PF09088.6_MIF4G_like_seed 9 205 !Q:0,1|24,24|34,65|67,69|72,74|89,89|92,93|96,96|133,134|136,136|157,159|168,168|171,171|174,175|194,194|203,203 Q:2,23|25,33|66,66|70,71|75,88|90,91|94,95|97,132|135,135|137,156|160,167|169,170|172,173|176,193|195,202|204,204 ??TTSHHHHHHHHHHHHHHHHHTT?HHHHHHHHH--------------------------------T???SS???HHHHHHHHHHHHHT?SS??SS?HHHHHHHHHHHHHHSTTTHHHHHHHHHHHHHHTGGG--B?HHHHHHHHHHHHHHHHTTTT???GGGGGGGT-TS?TT--SHHHHHHHHHHHHHHHTS?HHHHHHHS?G 1H2T|C PF09089.5_gp12-short_mid_seed 2 81 !Q:0,0|9,10|14,15|17,17|25,26|36,36|39,39|41,43|46,50|53,56|59,63|66,69|72,75|77,78 Q:1,8|11,13|16,16|18,24|27,35|37,38|40,40|44,45|51,52|57,58|64,65|70,71|76,76|79,80 ?HHHHTTSB??SSS??B?EEESSTT??BTTBSSEEE?TT?S???SS?????SS????SS?????SS????SS????S??EE 1PDI|A PF09090.6_MIF4G_like_2_seed 17 369 !Q:0,0|4,6|9,10|29,34|45,61|77,77|98,121|142,142|160,160|170,170|175,178|216,281|320,331|336,336|344,345|347,348|351,353 Q:1,3|7,8|11,28|35,44|62,76|78,97|122,141|143,159|161,169|171,174|179,215|282,319|332,335|337,343|346,346|349,350|354,368 ?TTS---SS??TTSTTHHHHHHHHHHHHT?-??--HHHHHHHHTT?????????????????HHHHHHHHHHHHHHT?SSHHHHHHHHHHTHHHHHHH------------------------TTSHHHHHHHHHHHHHHSTT?HHHHHHHHHHTTTTSSS?HHHHHHHHS-SGGG----SSSTTSSTTTTTHHHHHHHHHHHHHHHHHHHHHHHHS?--------------------------???-???---??????????------------------?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH------------HHHH-HHHHHHT??S??HH---HHHHHHHHHHHHHHT 1H2T|C PF09092.6_Lyase_N_seed 8 209 !Q:4,4|8,8|10,10|19,19|21,22|34,34|39,39|49,49|55,56|58,61|86,87|99,101|104,106|114,117|130,132|134,165|171,172|175,175|191,191|195,199|202,207 Q:0,3|5,7|9,9|11,18|20,20|23,33|35,38|40,48|50,54|57,57|62,85|88,98|102,103|107,113|118,129|133,133|166,170|173,174|176,190|192,194|200,201|208,208 BTTS?EEE?S?SSSTTTTE-E??TTEEEEEESSS?SSSS?EEEEEEETT?EEEEE??B????HHHHHHHHTSSEEEEEEEEEEESS??SSEEEEEEESS?-?TT???SEEEEEE????EEEEEEEETTTS--?B???????????????---??????????????EEEEE??TT?SEEEEEEEEEEEEEE-ETT?????SS?---??S 2Q1F|A PF09093.6_Lyase_catalyt_seed 4 389 !Q:0,1|3,12|25,26|33,46|61,62|66,66|69,69|73,73|75,76|78,78|88,88|90,90|93,94|103,103|123,123|126,126|148,148|152,153|157,157|183,183|195,196|205,206|210,212|231,231|233,233|252,252|254,256|259,259|263,263|267,267|275,276|295,295|300,302|325,326|330,330|333,333|337,340|342,343|354,355|359,361|364,364|376,388 Q:2,2|13,24|27,32|47,60|63,65|67,68|70,72|74,74|77,77|79,87|89,89|91,92|95,102|104,122|124,125|127,147|149,151|154,156|158,182|184,194|197,204|207,209|213,230|232,232|234,251|253,253|257,258|260,262|264,266|268,274|277,294|296,299|303,324|327,329|331,332|334,336|341,341|344,353|356,358|362,363|365,375 ??S??----????HHHHHHHHHHHH--HHHHHH?-------??????HHHHHHHHHHHHTT??EEE-TT-EEE?S??B?GGGGGGSTT-T?TT??TTHHHHTT?BHHHHHHHHHHHHHHHHTS?TT?HHHHHHHHHHHHHHHHHHHHT?STT??TTB?TTGGGTTTTHHHHHHTTHHHHHHTT?HHHHHHHHHHH--TTGGGGSS??SSS???HHHHHHTHHHHHHHHHTS?S?HHHHHHHHHHHHHHHHHH-S???TT?SSB?TTS?BEETTEE?-HHHHHHHHHHHHHHHHHH?SSTT???HHHHHHHHHHHHHHHHHSSSSB??GGG?TT?TTS--??B??HHHHHHHHTT??TTS?-?SS?HHHHHHHHHHT????????????? 2Q1F|A PF09094.6_DUF1925_seed 15 88 !Q:0,1|9,9|29,37|40,45|55,55|60,61|65,65|69,69 Q:2,8|10,28|38,39|46,54|56,59|62,64|66,68|70,87 ??GGGHHHH?HHHHHHHHHHHHHHHHTTT?--------HH------HHHHHHHTT?STTS??SSS?GGG?HHHHHHHHHHHHHHHTTS 1K1W|A PF09095.6_DUF1926_seed 21 321 !Q:0,0|7,7|13,13|35,36|44,51|55,85|92,95|98,100|108,108|111,112|120,121|123,125|128,128|132,133|138,138|142,145|151,152|162,163|173,175|186,193|196,198|207,216|218,239|242,245|257,257|262,262|268,269|287,287|307,310 Q:1,6|8,12|14,34|37,43|52,54|86,91|96,97|101,107|109,110|113,119|122,122|126,127|129,131|134,137|139,141|146,150|153,161|164,172|176,185|194,195|199,206|217,217|240,241|246,256|258,261|263,267|270,286|288,306|311,320 ?SSSSSS?EEEEE?SSEEEEEETTTTTEEEEEEET--TTTEETT????????GGG???----????????????????????????HHHHTT????SS???EEEEEEE?TT??HHHHHTT?-S???BS?SSS??EEEE?SSE----EEEEE??EEESSSEEE??EEEEEEEET---TEEEEEEEEE-------?SS???EEEEEEEE----------E?-------------------??SS????EEEEEEEEEEE?TTSS?EEEEE--EEEEEEEEEEEEEEEEE?SSSEEEEEEEEEEEEEEEE----SSEEEEEEEE 1K1W|A PF09096.5_Phage-tail_2_seed 6 173 !Q:3,6|11,23|26,26|37,38|54,54|59,61|65,65|68,69|76,76|101,102|111,112|115,116|119,119|125,125|128,131|133,133|144,144|147,148|157,157|160,165|167,169|171,171 Q:0,2|7,10|24,25|27,36|39,53|55,58|62,64|66,67|70,75|77,100|103,110|113,114|117,118|120,124|126,127|132,132|134,143|145,146|149,156|158,159|166,166|170,170|172,172 HHT????EEEE?????????????SS?EEEEEEEEES??SGGGSGGGSEEEEEE?TTSS???EEE?TT??EEEEEE?SGGGGGSSBSSSHHHHHHHHHHHT??EEEEEEEE??TT??TT?EEEEE?TT????S?EEEEEEEEEE?SS??EEEEEEEE?SS??????S???B?S 2Z6B|D PF09097.5_Phage-tail_1_seed 5 197 !Q:0,1|4,4|6,7|22,26|41,41|43,43|51,52|55,56|60,61|63,64|71,71|75,75|79,79|90,94|98,100|107,107|114,116|119,121|139,139|143,145|148,150|153,157|159,159|161,161|173,173|179,179|181,181|197,197 Q:2,3|5,5|8,21|27,40|42,42|44,50|53,54|57,59|62,62|65,70|72,74|76,78|80,89|95,97|101,106|108,113|117,118|122,138|140,142|146,147|151,152|158,158|160,160|162,172|174,178|180,180|182,196 ??TT?B??EEEEESSHHHHTTT?????TTSEEEEEEEEETT-S?EEEEEEE??TT??TTT??S??EEEEEE?BSS?TTS?EEEEEEEEEE?????SSS???EEEEEE?TTTTTT???BB???SBHHHHHHHHHHHHTSS?TTT???EE???EE?????B?S?HHHHHHHHHTT?EETTT?S?EEEEEETTEEEEEEH- 2Z6B|D PF09098.5_Dehyd-heme_bind_seed 11 169 !Q:0,1|15,15|21,22|30,30|33,33|49,53|69,71|78,78|85,85|88,93|95,95|106,106|115,116|131,131|162,162|164,165 Q:2,14|16,20|23,29|31,32|34,48|54,68|72,77|79,84|86,87|94,94|96,105|107,114|117,130|132,161|163,163|166,168 ??HHHHHHHHHBTTB?EEETT--EETTGGG?EE?HHHHHHHHHHHHHHH?????HHHHHHHHHHHHHHT???GGGSTT?TTTTTT?TT??????H-HHHHHHSSSS?SHHHHTEE??HHHHHHHHHHHHHH?GGGGGSTTTTTTTHHHHHHHTHHHHHHHHS?S??HHH 1JJU|A PF09099.5_Qn_am_d_aIII_seed 14 88 !Q:1,1|15,15|17,17|27,33|35,35|38,39|51,51|62,62|65,66|79,79 Q:0,0|2,14|16,16|18,26|34,34|36,37|40,50|52,61|63,64|67,78|80,87 S?EEEEEESSEEETT?E-EEEEEEEES?-----?S?EE??TTEEEEEEEEE?SSEEEEEEEE?TT??SEEEEEEETTEE-EEEEEEES 1JJU|A PF09100.5_Qn_am_d_aIV_seed 12 143 !Q:11,11|13,13|17,18|21,22|24,24|27,27|34,35|38,39|45,45|52,53|77,77|80,80|86,86|88,88|91,91|98,98|101,101|110,112|114,117|119,122|131,136|138,140|142,142 Q:0,10|12,12|14,16|19,20|23,23|25,26|28,33|36,37|40,44|46,51|54,76|78,79|81,85|87,87|89,90|92,97|99,100|102,109|113,113|118,118|123,130|137,137|141,141 EEEESSEEEEE?B?TTS--SS??B?EE?EEEEEE??SS??SSSTT?EEEEEE??EEEEEESSHHHHHHTHHHHSEEE?TT-SEEEE?B?SB?TTSGGG?BS?EEEEEEEE???T----T????EEEEEEEE?---??S???S? 1JJU|A PF09101.5_Exotox-A_bind_seed 2 274 !Q:0,3|9,9|12,12|16,17|22,22|29,30|33,39|51,63|79,79|81,82|86,86|89,89|108,108|110,110|127,127|138,138|144,144|146,148|154,155|177,183|196,197|199,201|220,220|225,244|250,254|257,257|260,266|272,273 Q:4,8|10,11|13,15|18,21|23,28|31,32|40,50|64,78|80,80|83,85|87,88|90,107|109,109|111,126|128,137|139,143|145,145|149,153|156,176|184,195|198,198|202,219|221,224|245,249|255,256|258,259|267,271 ????BHHHH?SS?EEE??BTTB?EEEEEE??TT????---SEEEEEEEEEE?????????-???EEEEEETTTEEEEEE?S??SSS?TT?EEEEEEEETTEEEEEEEE?S-SSEEEEEEEEEESTTS?SEEEEEEEEE?TTSEE?S???EEEEE??HHHHHHHHHEEEEEEEESSSS??-----EEEEEEEEEEEE??S???HHHHHGGGGSGGGGGGTS?HHHH????????????????????EEEEE?????EE?TT?????--EEEEE?? 2Q5T|A PF09102.5_Exotox-A_target_seed 2 143 !Q:2,2|14,16|22,23|26,30|51,52|63,63|68,68|107,107|110,111|129,131|135,138|140,141 Q:0,1|3,13|17,21|24,25|31,50|53,62|64,67|69,106|108,109|112,128|132,134|139,139|142,142 TS?HHHHHHHHHHH???HHHHS??SS?????HHHHHHHHHHHHHHHHHHTT??GGGTTHHHHS?GGGS?HHHHHHHHHHHHHHHHSTTHHHHHHHHHHHHHHHHHHH?TT??HHHHHHHHHHSEEEEEE???TTS????S??T 2Q5T|A PF09103.5_BRCA-2_OB1_seed 19 166 !Q:0,0|13,14|23,61|66,66|69,69|74,76|87,87|89,89|91,92|94,94|98,107|110,111|113,115|119,120|122,124|127,127|129,134|137,137|141,142|149,150|154,156|160,160|162,163|165,165 Q:1,12|15,22|62,65|67,68|70,73|77,86|88,88|90,90|93,93|95,97|108,109|112,112|116,118|121,121|125,126|128,128|135,136|138,140|143,148|151,153|157,159|161,161|164,164 ?HHHHHHTTSSTT??SEEEEEEE?????-------------?????????????????????EEEE?SS?EEEE???HHHHHHHHHT?S?T--T?EEE----------ES??E---EES??S???GG-G----??SS?EEE??TTTEEE??SSS--?SEE?S??S? 1MIU|A PF09104.5_BRCA-2_OB3_seed 5 148 !Q:0,4|10,10|13,15|26,27|30,31|33,34|38,39|45,45|48,49|58,64|67,69|72,72|82,85|88,88|91,91|105,105|123,124|130,130|143,147 Q:5,9|11,12|16,25|28,29|32,32|35,37|40,44|46,47|50,57|65,66|70,71|73,81|86,87|89,90|92,104|106,122|125,129|131,142 ?????GGGGG?TT???GGGEEEEEEE??EE--E??SSS??EEEEE?TT??EEEEEESS???----SS?-?TT?EEEEEEEEE?-??TT?SS?EEEEEEEEEEESS?SSHHHHHHHHHHHHHHH--HHHTT?HHHHHHHHHHTT????? 1MIU|A PF09105.5_SelB-wing_1_seed 2 61 !Q:0,16|18,46|49,56|59,59 Q:17,17|47,48|57,58|60,60 ?????????????????B?????????????????????????????EE????????EE?H 2PLY|A PF09106.6_SelB-wing_2_seed 67 65 !Q:11,11|15,16|25,26|31,31|34,38|58,58 Q:0,10|12,14|17,24|27,30|32,33|39,57|59,64 HHHHHHHHHHH?TTS??EEHHHHHH--HTSS-SS?----HHHHHHHHHHHHHTTSEEE?SSEEEE 2UWM|A PF09107.6_SelB-wing_3_seed 95 58 !Q:6,7|9,10|24,24|27,27|49,50|52,52|57,57 Q:0,5|8,8|11,23|25,26|28,48|51,51|53,56 HHHHHH--H--HSSEEHHHHHHHH-TS?HHHHHHHHHHHHHHTSEEEET--T-EEEE? 1WSU|A PF09108.5_Xol-1_N_seed 2 164 !Q:6,6|12,23|28,28|58,59|68,73|92,92|102,103|105,105|109,109|111,111|130,132|149,151 Q:0,5|7,11|24,27|29,57|60,67|74,91|93,101|104,104|106,108|110,110|112,129|133,148|152,163 EEEEEE?HHHHT????????????EEEE-EEEEEEETTTEEEEEEEEEEEEEEEEESS??SSGGGSEE??????TTHHHHHHHHHHHHHHHT?SSEEEEEEE??B?TTS?B?HHHHHHHHHHHHHTTSTT???HHHHHHHHHHHHHHTT???TTHHHHHHHHHH 1MG7|A PF09109.5_Xol-1_GHMP-like_seed 2 193 !Q:3,13|16,16|34,34|37,44|60,60|64,64|83,83|86,89|106,106|115,115|118,118|130,130|133,134|147,147|150,152|160,160|162,162|164,165|168,169|177,178|191,192 Q:0,2|14,15|17,33|35,36|45,59|61,63|65,82|84,85|90,105|107,114|116,117|119,129|131,132|135,146|148,149|153,159|161,161|163,163|166,167|170,176|179,190 EEE???????????EE?HHHHHHEEEEEEEETTS?SS????????HHHHHHHHHHHHHTT?SSS?GGGSHHHHHHHHHHHHHH?SS????HHHHHHHHHHHHHHHH?TTEEEEEE?SS?EEEEEETTGGG?HH--HHHHHHHHHHHH?SS???EEEEEEE?B?B??EE??TTTGGGS??EEEEEEEEEEEE?? 1MG7|A PF09110.6_HAND_seed 29 139 !Q:0,26|28,35|39,43|63,66|73,95|97,99|102,102|118,121|123,124 Q:27,27|36,38|44,62|67,72|96,96|100,101|103,117|122,122|125,138 ?????????????????--------??S????????GGG?????GGGHHHHHHHHHHHHHHHT????TTTTTT-----------------------T???SS?SSHHHHHHHHHHHHS????S??TTHHHHHHHHHHHS 2NOG|A PF09111.5_SLIDE_seed 36 124 !Q:31,31|38,45|49,49|53,55|57,57|72,75|90,90|96,96|103,103 Q:0,30|32,37|46,48|50,52|56,56|58,71|76,89|91,95|97,102|104,123 HHHHHTTHHHHHHHHHHHHHHHHHHHHHHHH?SSHHHH????----SSS?SSS???S?HHHHHHHHHHHHHH??-?SSSHHHHHHHHHHH?GGGSS?HHHHTS?HHHHHHHHHHHHHHHHHHHT 2Y9Z|A PF09112.5_N-glycanase_N_seed 16 212 !Q:10,12|16,17|21,24|27,28|44,49|51,51|53,53|66,73|75,76|81,82|85,86|89,89|92,92|96,96|101,108|115,115|120,120|125,127|135,136|143,145|148,148|156,156|159,163|165,165|172,172|182,182|191,193|197,202 Q:0,9|13,15|18,20|25,26|29,43|50,50|52,52|54,65|74,74|77,80|83,84|87,88|90,91|93,95|97,100|109,114|116,119|121,124|128,134|137,142|146,147|149,155|157,158|164,164|166,171|173,181|183,190|194,196|203,211 EEEEEEEEEE???TTT??SSS????TT??EEEGGGTEEEEEEEE??--??B?E-EEEEEEEEEESS---??---S??EEEE--EE??SS?SB?HHH-HHTT????????HHHHTT?TTSS?BTTB???EEEEEEE??SSTBTT?-?SS?GGGTTTS?TT?????S?EEEEEE?GGGGGGTBE-EEEEEEEE???SSS?-----EEEEEEEEE 3KS7|A PF09113.5_N-glycanase_C_seed 23 209 !Q:0,4|6,22|26,28|32,34|39,39|42,42|55,63|72,74|85,88|92,94|97,97|105,105|108,113|122,122|145,145|149,150|153,153|156,157|164,166|176,176|179,182|187,199 Q:5,5|23,25|29,31|35,38|40,41|43,54|64,71|75,84|89,91|95,96|98,104|106,107|114,121|123,144|146,148|151,152|154,155|158,163|167,175|177,178|183,186|200,208 ?????G-----------------GGT?-?EEE---EEEE?TT?EEEEEEEEEEEE?-------?STTSTTTS???EEEEETTEEE----EEE???BS?GGGGGGG?TT----??EEEEEEEE-EEEETTEEEEEEEEEEEEGGGS?BSS??TT?EE??EEEEEE???SEEEEEEEE?TT????BTTB?-----------?EEEEEEEEE 3KS7|A PF09114.5_MotA_activ_seed 3 97 !Q:0,1|13,13|15,15|32,32|39,39|41,41|45,45|72,72|95,97 Q:2,12|14,14|16,31|33,38|40,40|42,44|46,71|73,94 ??HHHHHHHTTTS-S?HHHHHHHHHHHHSTTB?HHHHHH-T?TTS?HHHHHHHHHHHHTTTSEEEETTEEEE?HHHHHHHHHHHHHHHHHTHHHH??- 1BJA|A PF09115.5_DNApol3-delta_C_seed 41 128 !Q:21,25|33,35|60,60|62,65|67,67|70,70|82,82|106,107|122,122|124,126 Q:0,20|26,32|36,59|61,61|66,66|68,69|71,81|83,105|108,121|123,123|127,127 TSSHHHHHHHHHHHHHHHHHH???--GGGHHHH?--STTHHHHHHHHHHHHHHHHHHHTT?S--??S?TT?HHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHHSTT??THHHHHHHHHHHHH-H---H 1XXH|E PF09116.5_gp45-slide_C_seed 9 129 !Q:6,6|22,23|33,34|42,42|46,46|49,50|52,52|60,60|62,64|66,68|78,81|83,85|87,87|96,99|109,109|112,112|114,115|120,121|124,124|127,128 Q:0,5|7,21|24,32|35,41|43,45|47,48|51,51|53,59|61,61|65,65|69,77|82,82|86,86|88,95|100,108|110,111|113,113|116,119|122,123|125,126 SEEEEE?HHHHHHHHHHHHHTT??EEEEEEETT--EEEEEEE?TTT?TT??S?SEEEEEE-E???S?-?EEEEEEGGG????S---S?EEEEEEEE----TTEEEEEEE?SS?E--EEEE??TT?EE?? 1B77|A PF09117.5_MiAMP1_seed 2 79 !Q:0,0|5,5|13,14|18,18|25,30|32,32|37,37|40,41|51,51|53,53|61,64|66,66|68,71|77,78 Q:1,4|6,12|15,17|19,24|31,31|33,36|38,39|42,50|52,52|54,60|65,65|67,67|72,76 ?EEEE?SSSSSSS??EEE?SSEEEE????--S?EEEE?SS??EEEESSGGG?S?EEEEESS??-?B?S????SEEEE?? 1C01|A PF09118.6_DUF1929_seed 68 150 !Q:0,2|8,21|25,28|32,32|39,48|51,58|66,67|74,75|77,78|82,92|97,100|104,104|109,112|114,114|116,117|119,119|122,122|132,132|135,140|142,144 Q:3,7|22,24|29,31|33,38|49,50|59,65|68,73|76,76|79,81|93,96|101,103|105,108|113,113|115,115|118,118|120,121|123,131|133,134|141,141|145,149 ???EEEES-----?--------SEE----ETT?EEEEEE----------SS------??SEEEEEE??EEETTB??S??EEE???--------EEEE----TTE-EEEE??--S?T--T-TS?SEEEEEEEE?TT?----?B???EEEEE 2WQ8|A PF09119.5_SicP-binding_seed 3 84 !Q:0,0|3,3|8,8|14,17|20,20|32,33|35,35|65,69|74,74|76,78|81,82 Q:1,2|4,7|9,13|18,19|21,31|34,34|36,64|70,73|75,75|79,80|83,83 ?SS?BTTB?EEEEE????TT?HHHHHHHHHHS??S?HHHHHHHHHHHHHTTSHHHHHHHHHHHHH?????GGGS?E---EE??S 1JYO|E PF09121.5_Tower_seed 9 42 !Q:3,3|12,12|22,41 Q:0,2|4,11|13,21 EEE?SSSSEEEE?HHHHHHHHH???????????????????? 1MIU|A PF09122.5_DUF1930_seed 3 70 !Q:7,9|13,13|15,16|18,18|21,22|33,34|44,44|48,48|58,58|64,66|69,69 Q:0,6|10,12|14,14|17,17|19,20|23,32|35,43|45,47|49,57|59,63|67,68 EEEEESS???TTS?B??T-TT??EEETTEEESS??HHHHHHHTT?BTT?EEEEEETTS?EEEEE?-?SS? 1OKG|A PF09123.6_DUF1931_seed 14 155 !Q:9,15|46,46|50,50|55,57|71,77|87,97|100,102|107,107|136,136|139,142 Q:0,8|16,45|47,49|51,54|58,70|78,86|98,99|103,106|108,135|137,138|143,154 HHHHHHHHH?????--GGGHHHHHHHHHHHHHHHHHHHHHHHHHTT?SEE?GGGS???HHHHHHHHHHHTT--?????HHHHHHHHH-----------TS???SSEE?HHHHHHHHHHHHHHHHHHHHHHHHHSTT?SS--??HHHHHHHHHHHH 1WWI|A PF09124.5_Endonuc-dimeris_seed 8 54 !Q:1,1|16,16|29,32|35,36|53,53 Q:0,0|2,15|17,28|33,34|37,52 B?THHHHHHHHHHHTS?HHHHHHHHHHTT????TT??HHHHHHHHHHHHHHHH? 2QNC|A PF09125.5_COX2-transmemb_seed 2 38 !Q:0,0 Q:1,37 ?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSG 4FA7|B PF09126.5_NaeI_seed 6 317 !Q:20,24|43,45|51,51|71,72|75,75|82,87|103,105|107,107|114,114|135,136|141,141|143,147|151,151|153,153|155,155|159,159|163,163|170,176|182,182|191,199|212,213|218,218|227,227|230,230|240,241|256,256|258,263|266,267|271,274|277,277|286,287|290,290|292,292|294,294|306,307|311,316 Q:0,19|25,42|46,50|52,70|73,74|76,81|88,102|106,106|108,113|115,134|137,140|142,142|148,150|152,152|154,154|156,158|160,162|164,169|177,181|183,190|200,211|214,217|219,226|228,229|231,239|242,255|257,257|264,265|268,270|275,276|278,285|288,289|291,291|293,293|295,305|308,310 THHHHHHHHHHHHHSSSSHH-----HHHHHHHHHHHHHTHHHH???SGGGS?HHHHHTHHHHHHHHHHHHH??EE?SSSSEE------ETTEEEEEEEESSTT???B?GGGTTS-EEEEEEEETTTTEEEEEEEE??GGGB?S?---?TTS?B?B?HHH-HTT?EESSTT???????GGGSS?HHHHHHHH?????????HHHHHHHHHHHH??SSEE?HHHHHHHH?SS?TGGGTSSSS--SSSSSSGGGTEEEE?S??????TT??SSS????SS?EEEEEEEE??SS?S-S?EEESSSSEEEE??TTS?????? 1EV7|A PF09127.6_Leuk-A4-hydro_C_seed 37 182 !Q:11,11|20,21|30,31|38,39|54,54|60,60|62,64|68,71|76,78|92,94|108,111|114,114|116,117|128,129|132,134|148,152|154,154|170,170 Q:0,10|12,19|22,29|32,37|40,53|55,59|61,61|65,67|72,75|79,91|95,107|112,113|115,115|118,127|130,131|135,147|153,153|155,169|171,181 HHHHHHHHHHH-HHHHHTTT??SHHHHHHH??GGGGTT??HHHHHHHHHHHHTT?SSTTS?S???GGG---?HHHH---HHHHHHTIIIIIT???HHHHHHHHHHHHH----TT?G--GGHHHHHHHT--TT???HHHHHHHHHHHHT-----T?HHHHHHHHHHHGGGS?HHHHHHHHHHT 3FUE|A PF09128.6_RGS-like_seed 9 246 !Q:6,6|11,14|17,17|33,35|45,45|51,52|54,54|74,75|78,82|90,118|126,128|150,162|171,171|183,186|188,188|191,194|201,201|209,211|216,218|222,224|244,246 Q:0,5|7,10|15,16|18,32|36,44|46,50|53,53|55,73|76,77|83,89|119,125|129,149|163,170|172,182|187,187|189,190|195,200|202,208|212,215|219,221|225,243 HHHHHH?HHHH----HH?HHHHHHHHHHHHHHS-??HHHHHHHHH-HHHTT--S?TTHHHHHHHHHHHHHTSTT?-TT?????HHHHHHH-----------------------------HHHHHTT???HHHHHHHHHHHHHHHHHHHHH-------------HHHHHHTT?GGGGTTTGGGG--??S?HH----HHHHHH-HHHHHHH---HHHH---HTS?--HHHHHHHHHHHHHHHHHTT??- 1IAP|A PF09129.6_Chol_subst-bind_seed 3 343 !Q:7,8|10,10|16,17|20,20|24,24|40,40|43,43|46,46|54,73|76,77|83,83|87,89|95,96|108,108|111,111|135,137|149,152|156,158|168,168|195,199|201,201|208,211|215,216|218,219|221,221|223,223|226,226|229,231|234,234|237,238|248,248|251,251|270,270|278,279|283,284|286,286|290,290|293,294|311,311|327,327|330,331|333,334|341,342 Q:0,6|9,9|11,15|18,19|21,23|25,39|41,42|44,45|47,53|74,75|78,82|84,86|90,94|97,107|109,110|112,134|138,148|153,155|159,167|169,194|200,200|202,207|212,214|217,217|220,220|222,222|224,225|227,228|232,233|235,236|239,247|249,250|252,269|271,277|280,282|285,285|287,289|291,292|295,310|312,326|328,329|332,332|335,340 EEEEEEE??S?HHHHT??TT?SSS?HHHHHHHHSEEEEEE?TT?SS?EEEEEEE????????????????????TT??TTSEE?SSS???TTTSS??HHHHHHHHHHH-TT?GGGHHHHHHHHHHHHHHHHHHTT?--SEEEEEHHHHH????TTS???EEEEEEEEE?GGGHHHHHHHHHHHHHHHHHHHHTTT?????S?EEEEEE????GGG??S??S?S?TT?TT???TT?TT??EEEEEEEEE?TT?TTHHHHHHHHHHHHHHHS?BTTEEEE??TTS??S?SSS-TT??HHHHHTHHHHHTTTTS?TTSSHHHHHHHHHHH?TT??S??HHHHHH?? 3JS8|A PF09130.6_DUF1932_seed 45 87 !Q:5,5|21,21|24,24|57,68|70,72 Q:0,4|6,20|22,23|25,56|69,69|73,86 HHHTT?HHHHHHHHHHHSTTS?HH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT?---------??H---HHHHHHHHHHHHHH 3QSG|A PF09131.5_Endotoxin_mid_seed 3 206 !Q:2,7|11,13|17,19|40,40|55,56|59,60|79,79|81,83|86,86|90,92|97,97|100,100|105,105|111,113|127,129|137,137|143,145|147,147|150,151|154,154|166,167|174,176|179,182|184,186|190,190|193,194|203,205 Q:0,1|8,10|14,16|20,39|41,54|57,58|61,78|80,80|84,85|87,89|93,96|98,99|101,104|106,110|114,126|130,136|138,142|146,146|148,149|152,153|155,165|168,173|177,178|183,183|187,189|191,192|195,202 EE??????EEE???SSS???EEEGGGHHHHHHHHTTTTTB?EEEEEEEEEEEEEE??SS??SEEEEEEEEEEEEEEGGG?B???EE?SSS???EEEE?SS?TTTS?EEEEE???EEEEETTTEEEEE???EEEESSS?EEESS???S?EE??TT?EEEEEEEEESS??HHHHTS???TT????B???TTS?TT??EEEEEEEE??? 1I5P|A PF09132.5_BmKX_seed 2 30 !Q:0,0|3,3|5,5|15,15|18,19|21,21|27,29 Q:1,2|4,4|6,14|16,17|20,20|22,26 ?SS?B?SSGGGGTTT?SS??B?SSBBS??? 1RJI|A PF09134.5_Invasin_D3_seed 2 99 !Q:0,1|5,5|11,11|19,21|28,28|30,30|34,34|36,37|39,40|50,51|54,56|59,59|62,62|69,69|72,72|86,86|90,90|97,98 Q:2,4|6,10|12,18|22,27|29,29|31,33|35,35|38,38|41,49|52,53|57,58|60,61|63,68|70,71|73,85|87,89|91,96 ??TTT?EEEES?SEEETTS???EEEEEE?B?TTS?B??S??SEEEEEEES??EE???EE?SS?EEEEEE?SS?EEEEEEEEETTEE?GGG?EEEEEE?? 1CWV|A PF09136.5_Glucodextran_B_seed 2 89 !Q:0,1|8,8|13,13|25,25|41,42|44,46|49,50|58,59|71,71|75,75|85,86 Q:2,7|9,12|14,24|26,40|43,43|47,48|51,57|60,70|72,74|76,84|87,88 ??EEEEES?SEEE?SSSEEEEEEEE?SSEEEEEETTEEEEE??B---TT--EEEEEEE??SSEEEEEEEEE?TTS?EEEEEEEEE??SE 1UG9|A PF09137.6_Glucodextran_N_seed 14 311 !Q:0,0|5,8|10,12|15,15|20,35|40,42|56,56|61,61|63,63|73,74|77,77|80,80|85,85|94,100|104,105|112,112|126,126|141,141|144,149|158,158|162,162|180,182|186,186|196,197|200,205|222,224|229,233|239,241|251,253|259,260|286,286|297,301 Q:1,4|9,9|13,14|16,19|36,39|43,55|57,60|62,62|64,72|75,76|78,79|81,84|86,93|101,103|106,111|113,125|127,140|142,143|150,157|159,161|163,179|183,185|187,195|198,199|206,221|225,228|234,238|242,250|254,258|261,285|287,296|302,310 ?TTTT????B???SB?SEEE??--------------SSTT???EEEEETTEEEEEE?SSTT?B?EEEEEEEEE?-SS?EE-EGGG?SEEEEEES?------TTS??EEEEEE?TTSSEEEEEEEEE?TTSSEEEEEEEEEE?SS---???EEEEEEEE?GGG?SSSEEEEEETTEEEEEE???SSS?EEEEEEETT??SE------EEEEETTTTSHHHHHH---HHSS?????SEEEE---ESEEEEEEE???SSSEE--EEEEEEEEESSHHHHHHHHHHHHHH?HHHHHHHHHH-----HHHHHHHHS 1UG9|A PF09138.6_Urm1_seed 29 133 !Q:6,6|15,15|17,19|24,31|35,38|51,52|54,55|57,57|61,90|94,95|115,118|121,121|130,132 Q:0,5|7,14|16,16|20,23|32,34|39,50|53,53|56,56|58,60|91,93|96,114|119,120|122,129 EEEEEE?SSGGGGGT-T???EEEE??------SSS????HHHHHHHHHHHH??S-?G-GGS--------------------------?-?-TTS??SSEEEEETTEEHHHHTTTS????TT?EEEEEETT??? 2AX5|A PF09140.6_MipZ_seed 12 269 !Q:0,0|6,6|10,10|29,30|36,37|41,41|58,58|60,65|69,69|73,73|81,81|100,100|108,109|112,112|122,122|140,140|142,150|152,153|171,175|177,178|186,187|190,191|211,211|216,220|231,232|235,235|237,237|242,242|245,247|266,266 Q:1,5|7,9|11,28|31,35|38,40|42,57|59,59|66,68|70,72|74,80|82,99|101,107|110,111|113,121|123,139|141,141|151,151|154,170|176,176|179,185|188,189|192,210|212,215|221,230|233,234|236,236|238,241|243,244|248,265|267,268 ?EEEEE?SSS?TTHHHHHHHHHHHHHHTT??EEEEE??TTT?HHHHHHHHHHHHHHHT-T??????EEE?SSS?HHHHTTS?HHHHHHHHHHHHHHHHHH?SEEEEEE??SS?HHHHHHHHT?SEEEEEEESSHHHHGGG?B?????????B??HHHHHHHHHHHHHHHTT---??S??EEEEEEE??TT??GGGHHHHHHHHHHHHHHHT?EEEE?????HHHHHHGGGT??GG-G?SSSS?SS???HHHHHHHHHHHHHHHHTT?GG 4E03|A PF09141.5_Talin_middle_seed 6 167 !Q:22,22|25,34|36,36|75,75|79,80|115,116|138,138|141,145|147,147 Q:0,21|23,24|35,35|37,74|76,78|81,114|117,137|139,140|146,146|148,166 HHHHHHHHHHHHHHHHHHHHTT?SS???--?????S?HHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS?TTT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSS??HHHHHHHHHHHHHHHHHHHHH?TT?---?S?THHHHHHHHHHHHHHHHHH 1SYQ|B PF09142.6_TruB_C_seed 34 63 !Q:5,6|17,19|21,29|31,31|36,36|40,40|46,48|62,62 Q:0,4|7,16|20,20|30,30|32,35|37,39|41,45|49,61 SEEEE??HHHHHHHHTT???B??----???S?EEEE?TTS?EEEEE---EEETTEEEEEEES? 1SGV|A PF09143.5_AvrPphF-ORF-2_seed 4 192 !Q:0,0|5,9|15,15|27,27|34,35|38,38|45,45|50,53|60,60|63,66|77,77|79,79|84,85|88,89|95,103|116,116|118,118|131,142|157,158|163,170|173,173|180,181|184,184|188,188|191,191 Q:1,4|10,14|16,26|28,33|36,37|39,44|46,49|54,59|61,62|67,76|78,78|80,83|86,87|90,94|104,115|117,117|119,130|143,156|159,162|171,172|174,179|182,183|185,187|189,190 ?TTTT?????BGGGS?HHHHHHHHHHH?HHHHTT??TT?EEEEEE?HHHH----TTSEEE?BS????EEEEEEEEEE?T-TTTT--TT??TTSGG---------GEEEEEEEGGGG?S?EEEEEESTTTTT???????--???EEEEEEHHHHHTTT??EEEB????????SS?EEEEEE??TT?EEE?EE? 1S21|A PF09144.5_YpM_seed 2 117 !Q:0,0|11,11|14,14|19,25|27,29|37,38|41,43|51,52|56,59|64,64|71,71|73,76|80,80|88,89|92,92|100,107|109,109|113,116 Q:1,10|12,13|15,18|26,26|30,36|39,40|44,50|53,55|60,63|65,70|72,72|77,79|81,87|90,91|93,99|108,108|110,112 ?SSSEEEEEEE?SS?EEEE???????S???TTEEEEE??SS???EEEEEEE??SSS????SEEE?TTEEEE?S????TTS?EEEEEEE??SS?EEEEEEE????????S?SSS???? 1POQ|A PF09145.5_Ubiq-assoc_seed 4 46 !Q:0,0|16,18|30,30|43,46 Q:1,15|19,29|31,42 ?SHHHHHHHHHHHHHH???SHHHHHHHHHH?SSHHHHHHHHHS???- 1PGY|A PF09147.5_DUF1933_seed 3 201 !Q:0,1|8,9|21,21|38,39|45,45|55,56|58,58|70,70|76,77|90,90|97,98|107,107|111,111|117,117|123,124|137,137|146,146|151,151|153,154|161,161|163,165|168,169|177,178|188,188|191,192 Q:2,7|10,20|22,37|40,44|46,54|57,57|59,69|71,75|78,89|91,96|99,106|108,110|112,116|118,122|125,136|138,145|147,150|152,152|155,160|162,162|166,167|170,176|179,187|189,190|193,200 ??EEEEET??HHHHHHHHTTS?EEEEEETTEEEEEETT??EEEEE?SSSEEEEEE??S?HHHHHHHHTTT?GGGGG??HHHHHHHHHHHH?GGGGGG??SSEEEEEE?TTS?EEEEE?SSSSS??EEEESSSEEEES?HHHHHHHH?TTSS?B??HHHHTT?S???TT??SBTTEEE??SSEEEEEEE?TT??EEEEEEES 1Q15|A PF09148.5_DUF1934_seed 66 163 !Q:1,6|15,21|23,24|29,29|46,46|57,58|63,65|74,75|85,87|97,97|102,102|129,129|133,135|146,156 Q:0,0|7,14|22,22|25,28|30,45|47,56|59,62|66,73|76,84|88,96|98,101|103,128|130,132|136,145|157,162 E------EEEEEEEE-------E--ETTE-EEEEEEEEEEEEEEET-TEEEEEEEEE--ETTE---EEEEEEEE--ETTEEEEEE---EESSBEEEE-EETT?EEEEEEEETTEEEEEEEEEEEEEEEE?SSE---EEEEEEEEEE----???????EEEEEE 1R0U|A PF09149.5_DUF1935_seed 71 176 !Q:2,7|9,17|29,47|55,55|57,72|77,78|84,85|100,102|104,107|110,110|113,115|119,127|129,129|134,141|149,149|152,152|158,158|161,164|169,169 Q:0,1|8,8|18,28|48,54|56,56|73,76|79,83|86,99|103,103|108,109|111,112|116,118|128,128|130,133|142,148|150,151|153,157|159,160|165,168|170,175 SS??---?S---??---?SEEEESSSSTT---------?---------SEEEEEE-T----------------TTTE--EEEEE??SSEEEEEEEEEESS??-E----EE?TT?--EEE---------E?TTSE--------EEEEEEE?TT?EEEEE-EE??-?SEEE-EEEEEE 1R75|A PF09150.5_Carot_N_seed 8 165 !Q:0,0|11,12|14,14|28,28|47,53|56,57|73,73|77,77|89,91|101,101|122,123|125,125|128,131|145,145|160,164 Q:1,10|13,13|15,27|29,46|54,55|58,72|74,76|78,88|92,100|102,121|124,124|126,127|132,144|146,159 ?HHHHTTSSTT??B?THHHHHHHHHHTS?HHHHHHHHHHHHHHHTTT???????HH--HHHHHHHHHHHHHHS?HHH-HHHHHHHHHHT???HHHHHHHTB?HHHHHHHHHHHHHHHHHTSS??S?TT????HHHHHHHHHHHTS?HHHHHHHHHHHHHT????? 3MG1|A PF09151.5_DUF1936_seed 2 36 !Q:0,1|3,3|16,16|20,20|28,28|31,33|35,35 Q:2,2|4,15|17,19|21,27|29,30|34,34 ??B?TTTSSSBEEEEE?TTS?EEEEEES?TT???B? 1PVM|A PF09152.5_DUF1937_seed 7 123 !Q:0,0|6,18|43,43|53,56|63,63|67,67|86,86|92,94|100,100|115,115 Q:1,5|19,42|44,52|57,62|64,66|68,85|87,91|95,99|101,114|116,122 ?EEEEE????--------?SSHHHHHHHHHHHHHHHHHHHHTT?EEEEHHHHH----HHHHTT?TTS?HHHHHHHHHHHHHHHHHH?SEEEE???TTGGG?HHHHHHHHHHHHTT?EEEEHHH 1T1J|A PF09153.5_DUF1938_seed 4 89 !Q:0,0|38,38|51,51|53,58|60,62|77,77|84,85|88,88 Q:1,37|39,50|52,52|59,59|63,76|78,83|86,87 ?EEEEEEEETTEEEEEEEEESSSEEEEEEESSHHHHHH-HHHHHHHHHHHT-T??????B???SHHHHHHHHHTTSS?GGGGGG--GB? 1MGT|A PF09154.5_DUF1939_seed 9 68 !Q:5,5|7,7|11,11|18,18|31,31|36,37|42,42|45,45|52,53 Q:0,4|6,6|8,10|12,17|19,30|32,35|38,41|43,44|46,51|54,67 EEEEE-E?SSS?EEEEEE?GGGTTEEEEESS?TTSS??EEEE?TT?EEEEEE??EEGGGTEESEEEEE 2GJP|A PF09155.5_DUF1940_seed 3 143 !Q:12,12|35,35|57,63|73,79|88,88|121,122|142,142 Q:0,11|13,34|36,56|64,72|80,87|89,120|123,141 EETTTTEEEETT?HHHHHHHHHHHHHHHHHHHHHT?SSHHHHHHHHHHHHHHHHTTT???????HHHHHHHHH???????HHHHHHHT?HHHHHHHHHHHHHHHHHHHHHHHHTSTTTTTT??HHHHHHHHHHHHHHHHHHH? 1NIG|A PF09156.5_Anthrax-tox_M_seed 2 287 !Q:21,22|35,35|37,39|48,48|59,59|63,63|66,67|81,105|121,121|123,123|134,134|137,137|141,141|159,161|164,165|168,168|171,171|178,178|192,192|195,195|200,200|211,212|217,217|219,220|226,230|233,234|241,242|245,245|258,258 Q:0,20|23,34|36,36|40,47|49,58|60,62|64,65|68,80|106,120|122,122|124,133|135,136|138,140|142,158|162,163|166,167|169,170|172,177|179,191|193,194|196,199|201,210|213,216|218,218|221,225|231,232|235,240|243,244|246,257|259,286 HHHHHHHHHHHHHHTHHHHHH??HHHHHHHHHTTS?B???HHHHHTTS?HHHHHHHHHS?STT?SS??HHHHHHHHHHHTT?????????????????????????HHHHHHHHHHHHHTS?B?HHHHHHHHTT?TT?SSS?HHHHHHHHHHHHHHHHH???BS??SS?SS?EEEEEE?THHHHHHHHTTSB?SS?TTSB?HHHHHHHHTT??EEEE?S??EEESS?????TT??EEEEEE??TT?BEEEETTTEEEE?SSEEEEEEEEEEEEETTEEEEEEEEEEE 1ZXV|A PF09157.6_TruB-C_2_seed 98 84 !Q:0,0|5,5|16,17|19,33|36,37|39,40|43,43|50,54|60,61|69,69|73,76|83,83 Q:1,4|6,15|18,18|34,35|38,38|41,42|44,49|55,59|62,68|70,72|77,82 ?EEEE?HHHHHHHTTT??B----------??---SS??S--SS-EEEEEE-----TTTTE--EEEEEEE?TTS---?EEEEEE? 1ZL3|A PF09158.5_MotCF_seed 3 105 !Q:0,1|20,21|41,41|50,50|62,63|75,75|80,80|84,84|92,93 Q:2,19|22,40|42,49|51,61|64,74|76,79|81,83|85,91|94,104 ??HHHHHHHHHHHHHHHHTT??EEEEEEETTEEEEEEEEEE-TTEEEEEE?TTSEEEEEEES??HHHHHHHHTTT?EEEE?TTS-EEEEEEE??HHHHHHHHHHH 1KAF|A PF09159.5_Ydc2-catalyt_seed 53 510 !Q:1,4|10,10|22,52|56,56|58,85|92,95|98,98|101,178|180,181|184,191|209,209|213,222|230,233|235,235|238,239|264,285|290,291|301,338|342,352|366,389|395,408|418,419|424,483|496,496 Q:0,0|5,9|11,21|53,55|57,57|86,91|96,97|99,100|179,179|182,183|192,208|210,212|223,229|234,234|236,237|240,263|286,289|292,300|339,341|353,365|390,394|409,417|420,423|484,495|497,509 E----EEEEE?STTEEEEEEEE------------------------------?TTS?E----------------------------EEEEEE----EE?TT------------------------------------------------------------------------------S??TT????????SHHHHHHHHHHHHHHHH-HHH?-----?---SEEEEEE????T-TT??HHHHHHHHHHHHHHHHHHHHHHHH?????????------------?EEEE??HHHHHHHHH--------------------------------------HHH???????????HHHHHHHHHHTTS------------------------EEESS--------------HHHHHHHHH??STTT------------------------------------------------------------HHHHHHHHHHHH-HHHHHHHHHHHHH 1KCF|A PF09160.5_FimH_man-bind_seed 6 170 !Q:6,6|9,9|11,13|15,15|23,25|28,29|32,33|35,35|42,44|50,50|52,52|55,55|57,58|69,69|76,82|98,98|101,105|109,110|113,113|116,117|125,125|128,129|134,134|137,137|151,152|155,156|159,165 Q:0,5|7,8|10,10|14,14|16,22|26,27|30,31|34,34|36,41|45,49|51,51|53,54|56,56|59,68|70,75|83,97|99,100|106,108|111,112|114,115|118,124|126,127|130,133|135,136|138,150|153,154|157,158|166,169 EEETTS?EE?T---T?EEEEEEE???SB??TT??E-EEEGGG---TEEEE?S?TT-T??EEEEEEEEEE?HHHHHH-------EEEEEEETTEEEEES?SS??-??EEE??SS?EE??EEEEEEE?TT??EEEE?TT?EEEEEEEEEEESS--SS??EE-------EEEE 4AUY|A PF09162.5_Tap-RNA_bind_seed 12 90 !Q:0,7|20,20|35,38|68,68|70,70|74,74|76,78|84,85|87,89 Q:8,19|21,34|39,67|69,69|71,73|75,75|79,83|86,86 ????--??EEEEEETTGGGS?HHHHHHHHHHHSSS????EEEEEETTEEEEEESSHHHHHHHHTTTTT?B?TTS?B???EEEEE??S??? 1FO1|A PF09163.6_Form-deh_trans_seed 40 49 !Q:0,1|9,9|35,36|38,38|40,44 Q:2,8|10,34|37,37|39,39|45,48 ??HHHHHHH-TTHHHHHHHHHHHHHHHHHHHHHHH??B?S?----SSTT 1KQF|B PF09164.5_VitD-bind_III_seed 6 68 !Q:9,9|25,25|28,29|52,53|67,67 Q:0,8|10,24|26,27|30,51|54,66 HHTTTTTTS?HHHHHHHHHHHHHHH?TT??HHHHHHHHHHHHHHHHHHSSTT??HHHHHHHHHHHHT? 1LOT|A PF09165.5_Ubiq-Cytc-red_N_seed 16 78 !Q:0,0|7,7|9,11|18,19|21,24|26,26|35,42|45,47|50,50|52,77 Q:1,6|8,8|12,17|20,20|25,25|27,34|43,44|48,49|51,51 ?SHHHHT?S???EEESSS??B????S-SSTTTSSS????????TT???SS?S?????????????????-???????? 1SQB|I PF09166.5_Biliv-reduc_cat_seed 4 115 !Q:11,12|23,26|31,32|49,49|51,51|75,75|79,79|88,88|91,93|104,104|107,112|114,114 Q:0,10|13,22|27,30|33,48|50,50|52,74|76,78|80,87|89,90|94,103|105,106|113,113 HHHHHHHHHTT??EEEEEEEEEE????HHHH??HHHHTHHHHHHHHHHH?S?EEEEEEEEEEGGGTEEEEEEEEE?TTS?EEEEEEEE?TT???EEEEEEEESS?EE??????S? 1LC3|A PF09167.6_DUF1942_seed 13 130 !Q:0,2|9,9|32,37|40,42|58,58|60,62|70,70|73,74|79,80|84,84|88,92|94,94|97,97|108,109|112,114|119,119|121,121 Q:3,8|10,31|38,39|43,57|59,59|63,69|71,72|75,78|81,83|85,87|93,93|95,96|98,107|110,111|115,118|120,120|122,129 ???EEEETT?EEEEEETTTTEEEEEEEEEEEE??????SS???SEEEEEEEEEEEEES?B???GGGEEEE?TT??EEEB??SSS?TTB?????B?TT?EEEEEEEEEE-?SS???EEEE-E?SSSEEEEE 1LMI|A PF09168.5_PepX_N_seed 24 162 !Q:0,6|8,13|26,32|36,36|48,57|61,61|65,65|67,67|71,71|81,85|99,100|106,106|109,109|119,126|128,130|146,146 Q:7,7|14,25|33,35|37,47|58,60|62,64|66,66|68,70|72,80|86,98|101,105|107,108|110,118|127,127|131,145|147,161 ????--?S??????HHHHHHHHHHHT??---??TTS?HHHHHHHHHHT----------SSS?GGG?B?SSS?BHHHHHHSS-????HHHHHHHHHHHTT??BTTTB?TT?HHHHHHHTT??---???S???HHHHHHHHHHHHHSB?TTSSBHHHHHHHTTS 1LNS|A PF09169.5_BRCA-2_helical_seed 5 201 !Q:0,1|3,3|8,13|29,35|44,44|46,47|57,57|59,62|65,68|70,70|74,76|82,83|90,93|101,101|106,106|109,109|112,112|116,118|121,123|127,129|143,144|148,149|171,171|175,175|200,200 Q:2,2|4,7|14,28|36,43|45,45|48,56|58,58|63,64|69,69|71,73|77,81|84,89|94,100|102,105|107,108|110,111|113,115|119,120|124,126|130,142|145,147|150,170|172,174|176,199 ??S?HHHH------HHHHHHHHHHHHHTS???????HHHHHHTS?S??EETTGGGTS?S????TT---?S?SSS???SSSSS??TTTTTT????THHHHTT-TSTT?TT?EE?TTS?--EE???TTS???HHHHHHHHHHSTT??TTS??HHHHHHHHHHHHHHHHHTSTT?TTT?SSSSSSHHHHHHHHHHHHHHHTTS? 1MIU|A PF09170.5_STN1_2_seed 6 181 !Q:0,35|40,40|45,45|66,67|76,76|78,78|86,87|92,104|128,129|133,133|143,143|160,161|165,165 Q:36,39|41,44|46,65|68,75|77,77|79,85|88,91|105,127|130,132|134,142|144,159|162,164|166,180 ------------------------------------HHHH?GGGS?HHHHHHHHHHHHHHHHHHTT??EEEHHHHH-T?HHHHHHH??HHHH?????????????HHHHHHHHHHHHHHHHHHTTSEE??SSS?TTEEEEGGG?HHHHHHHHHHHHTGGG??TTS?SSEEHHHHHHHHHHH 1WJ5|A PF09171.5_DUF1886_seed 19 281 !Q:8,8|19,20|34,35|50,51|53,53|56,56|68,73|78,83|97,97|101,101|117,120|122,132|134,134|149,149|172,177|181,185|197,207|210,210|216,216|235,236|246,246|255,256|261,270|272,272 Q:0,7|9,18|21,33|36,49|52,52|54,55|57,67|74,77|84,96|98,100|102,116|121,121|133,133|135,148|150,171|178,180|186,196|208,209|211,215|217,234|237,245|247,254|257,260|271,271|273,280 HHHHHTTS?HHHHHHHHTT-?HHHHHHHHHHHHH-?HHHHHHHHHHHHHT??S?SS?HHHHHHHHHHH------HHTS----??SSHHHHHHHHHHH?TTS?TTHHHHHHHHHHHTT????T-----------T?HHHHHHHHHHHHTS?TTSHHHHHHHHHHHHHHHHHHT??????TTS?????HHHHHHHHHTT?---------?SS?HHHHH-HTHHHHHHHHHHHHHHHT??HHHHHHHHH-HHHHHHHH??STTS----------S?HHHHHHTT 1XQP|A PF09172.6_DUF1943_seed 71 433 !Q:2,2|19,21|51,52|63,63|71,189|191,203|223,231|233,252|262,268|271,271|273,273|278,279|295,295|311,311|320,320|323,323|325,325|327,328|331,332|335,337|343,343|366,366|368,368|370,370|373,374|400,400|407,414|416,416|423,424|426,426 Q:0,1|3,18|22,50|53,62|64,70|190,190|204,222|232,232|253,261|269,270|272,272|274,277|280,294|296,310|312,319|321,322|324,324|326,326|329,330|333,334|338,342|344,365|367,367|369,369|371,372|375,399|401,406|415,415|417,422|425,425|427,432 TS?EEEEEEEEETTTTEEE---EEEEEEEEETTEEEEEEEEEEEEEEETTE--EEEEEEEEEE?HHHHHHH??--------------------------------------------------------------????????????????????????????????????-????????------????S-------------EEEEEEETTEEEEEEEEST---------T????????????????????HHHHHHHHH-------HH-T?EEEE--EEEEEEEEEEEEEEE?TTSSEEEEEEEEEEE-EEEEEEEE-EE?S-S??TT??HH---HHTTS?EEEEEEEEEEEEEEEEEEEEEE?S-S?EE--EEEEEEEEEEEEEEEEEEEEETTTT-EEEEEE?--??--?S?EEEEEE--E-EEEEEE 1LSH|A PF09173.6_eIF2_C_seed 36 97 !Q:6,6|11,27|29,33|36,36|56,57|71,72|75,76|97,97 Q:0,5|7,10|28,28|34,35|37,55|58,70|73,74|77,96 EEEEEE-EEEE?????????------??S?????TT?EEEEEETTEEEEEEEEEEE--TTEEEEEEEEEEE??TT?-EEEEEEEETTEEEEEEEEEE- 3QSY|A PF09174.5_Maf1_seed 21 244 !Q:0,0|2,2|11,92|95,95|97,97|115,118|120,120|122,123|130,130|132,132|153,179|195,197|201,201|207,211|215,215|218,219|221,223|225,225 Q:1,1|3,10|93,94|96,96|98,114|119,119|121,121|124,129|131,131|133,152|180,194|198,200|202,206|212,214|216,217|220,220|224,224|226,243 ?B?EEEEEEEE?------------------------------------------------------------------------------???TT?S?HHHHHHHHHHHHHHTTT-???T-T??GGGEEE?S?HHHHHHHHHHHHHHHHGGGH---------------------------HHHHHHHHHHHHHHH?--GGG?EEEEE?--??GGG?TT-?S???S?EEEEEEEETTTTEEEEEE 3NR5|A PF09175.5_DUF1944_seed 30 176 !Q:0,1|9,10|13,16|26,26|31,32|42,42|45,47|55,56|61,61|73,73|87,87|100,103|108,110|122,123|132,132|137,138|140,140|162,162|165,165|174,174 Q:2,8|11,12|17,25|27,30|33,41|43,44|48,54|57,60|62,72|74,86|88,99|104,107|111,121|124,131|133,136|139,139|141,161|163,164|166,173|175,175 ??EEEEEEE??SS????EEEEEEEEE?HHHH??EEEEEEEES?TT???EEEEEEE??SSSE-EEEEEEESSSS?SEEEEEEEEEEES-SSSEEEEEEEEE????HHHH---HHHHHHHHTHH--HHHHHTTT?EEES??S?TTEEEEEEEEEETTEEEEEEE?SS?EEEEEEEE?S 1LSH|B PF09176.6_Mpt_N_seed 17 83 !Q:11,11|20,21|36,37|50,50|52,52|67,67|72,73|76,77|80,80 Q:0,10|12,19|22,35|38,49|51,51|53,66|68,71|74,75|78,79|81,82 HHHHHHHHHTT?SEEEEESS??TTTHHHHHHHHHSS??GGGGGGEEEEEE?S?HHHHHHHHHHHHHH?BTTB??EE--EE?ST 1LU9|A PF09177.6_Syntaxin-6_N_seed 43 124 !Q:0,1|17,20|30,52|82,86|90,93|98,101 Q:2,16|21,29|53,81|87,89|94,97|102,123 ??HHHHHHHHHHHHHHH----HHHHHHHHH???????------------????HHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----HHH?---HHHH-???HHHHHHHHHHHHHHHHHHHHHH 2C5J|A PF09178.5_DUF1945_seed 2 51 !Q:0,0|8,8|13,13|30,30|34,35|42,43|46,46|50,50 Q:1,7|9,12|14,29|31,33|36,41|44,45|47,49 ?EEEEEEE?SSEE-EEEEEETTEEEEEEEE?SSS??EETTEE??TT?EEE? 1LWH|A PF09179.6_TilS_seed 123 82 !Q:5,6|11,11|27,29|31,36|51,54|58,59|64,64|66,68 Q:0,4|7,10|12,26|30,30|37,50|55,57|60,63|65,65|69,81 EESGG--GTTS?HHHHHHHHHHHHHHT---T?-????HHHHHHHHHHTTTS?---GGG??EEEE-T---TEEEEESSSEEEE 3A2K|A PF09180.6_ProRS-C_1_seed 82 123 !Q:4,15|20,20|24,28|35,38|51,72|78,78|81,82|84,89|92,94|97,97|99,108|110,113|120,120|122,122 Q:0,3|16,19|21,23|29,34|39,50|73,77|79,80|83,83|90,91|95,96|98,98|109,109|114,119|121,121 HHHH------------HHHH-HTT----?EEEEEE???-HHHHHHHHHHHH?????--------?????????EEEEE-ES--S-----?SS???TT?B??---???-?B??--EEEEEE?B? 1NJ2|A PF09181.5_ProRS-C_2_seed 4 68 !Q:3,3|6,7|10,15|25,25|32,33|37,37|48,48|55,55|65,65|67,67 Q:0,2|4,5|8,9|16,24|26,31|34,36|38,47|49,54|56,64|66,66 EEE?SS??HH------HHHHHTTTT?SEEEEE??GGG?SHHHHHHHSS?EEEEEE?SSSEEEEEE?B? 1NJ8|A PF09182.5_PuR_N_seed 37 70 !Q:0,0|18,19|31,32|59,59|63,63 Q:1,17|20,30|33,58|60,62|64,69 ?HHHHHHHHHHHHHTSTT??EEHHHHHHHHT??HHHHHHHHHHHHHHHHHTTSEEEEEE?STT?EEEEEE 1P4A|A PF09183.5_DUF1947_seed 7 67 !Q:0,1|4,5|19,19|22,24|27,30|35,35|38,38|58,58|66,66 Q:2,3|6,18|20,21|25,26|31,34|36,37|39,57|59,65 ??EE??HHHHHHHHHHHHT-TT???TT-???EEEE?SS?EEEEETTEEEEEESSSEEE?HHHHHHS? 1Q7H|A PF09185.5_DUF1948_seed 2 140 !Q:0,1|20,23|35,36|40,42|70,72|74,87|105,107|124,126|130,130|132,132|137,139 Q:2,19|24,34|37,39|43,69|73,73|88,104|108,123|127,129|131,131|133,136 ??HHHHHHHHHHHHHHHGGG????HHHHHHHHHHT??TTT???HHHHHHHHHHHHHHHHHHHHHHHHHHH???S??????????????HHHHHHHHHHHHHHHHH???HHHHHHHHHHHHHHTT???TTS?S?TTTS??? 1Q8C|A PF09186.6_DUF1949_seed 181 63 !Q:3,3|16,18|20,20|23,24|35,36|44,44|62,62 Q:0,2|4,15|19,19|21,22|25,34|37,43|45,61 EEE?TTTHHHHHHHHH---H-TT-?EEEEEEESSS--EEEEEEE?SSTHHHHHHHHHHHHTT? 2CVE|A PF09187.5_DUF1950_seed 3 121 !Q:4,4|16,18|21,23|25,28|43,47|64,64|67,70|76,76|95,96|107,107|115,120 Q:0,3|5,15|19,20|24,24|29,42|48,63|65,66|71,75|77,94|97,106|108,114 THHH-HHHHHHHHHTS???SS?-?S????SSHHHHHHHHHHHH?????HHHHHHHHHHHHTTTT?SS????GGGTS?HHHHHHHHHHHHHHHHHS??HHHHHHHHHH?TTGGGGS?????? 2Q3T|A PF09188.5_DUF1951_seed 2 137 !Q:0,4|17,18|42,42|54,54|76,77|80,82|90,90|108,108|110,114|117,117|135,136 Q:5,16|19,41|43,53|55,75|78,79|83,89|91,107|109,109|115,116|118,134 ?????HHHHHHHHHHTT??SSTHHHHHHHHHTTSSSSSSSSS?HHHHHHHHTTS?SHHHHHHHHHHHHHHHHHHTT??SS???STHHHHS?HHHHHHHHHHHHHHHTT?S?????SS?HHHHHHHHHHHTHHHHT?? 1TM9|A PF09189.5_DUF1952_seed 2 78 !Q:8,9|22,22|77,77 Q:0,7|10,21|23,76 EEEEEEET??HHHHHHHHHHTT?EEEETTEEEETTEEEEEEEEEEEEETTEEEEEEEEEEEETTHHHHHHHHHHHHT? 1V8C|A PF09190.6_DALR_2_seed 124 104 !Q:10,10|28,36|41,46|51,54|58,59|61,66|73,76|82,84|86,86|88,96|98,99|103,103 Q:0,9|11,27|37,40|47,50|55,57|60,60|67,72|77,81|85,85|87,87|97,97|100,102 HHHHHHHBTS?HHHHHHHHHHHHHHHHH---------HHHH-----?HHHH----HHH--H------HHHHHH----HTTTT?--S?S--------?H--HHH? 1LI5|A PF09191.5_CD4-extracel_seed 11 113 !Q:1,1|12,13|18,25|28,28|36,36|41,46|53,53|56,56|64,64|67,68|70,71|76,76|84,84|88,88|96,96|102,103 Q:0,0|2,11|14,17|26,27|29,35|37,40|47,52|54,55|57,63|65,66|69,69|72,75|77,83|85,87|89,95|97,101|104,112 S?SEEEEEEETB??EEEE????????SS?EEEEEEE-EESS??????EEEEEE?SS?EEEEEEE?SS??B??SSSS?EEEESSB?GGG?EEEEEEE?BTTTT??EEEEEEEEE 1WIP|A PF09192.5_Act-Frag_cataly_seed 7 460 !Q:0,8|12,13|15,15|17,17|20,22|25,25|35,53|58,58|67,115|121,122|125,127|143,147|167,174|177,177|181,181|189,189|192,196|202,205|212,213|216,223|230,230|248,301|303,304|308,311|315,315|317,319|329,332|335,335|339,339|341,350|353,378|394,397|401,402|405,419|433,435|441,443|449,453 Q:9,11|14,14|16,16|18,19|23,24|26,34|54,57|59,66|116,120|123,124|128,142|148,166|175,176|178,180|182,188|190,191|197,201|206,211|214,215|224,229|231,247|302,302|305,307|312,314|316,316|320,328|333,334|336,338|340,340|351,352|379,393|398,400|403,404|420,432|436,440|444,448|454,459 ?????????TTT??B?S?TT???TT?GGGEEEEEE?-----------------?STTS?EEEEEESS?------------------------------------------------EEEEE??TT---HHHHHHHHHHHHHHT?????EEEEESSSHHHHHHHHHHH--------HH?SSS?HHHHHTT?SE-----EEEEE???-EEESTT??SS--------SHHHHS?HHHHHHHHHHHHHHHHH------------------------------------------------------T??SSS?---SSS?S???GGGEEEESB----TT?EEE?S????---???SS-------------------------?THHHHHHHHHHHHHH---?TTS??HH---------------HHHHHHHHHHHHT???TTHHH---HHHHH-----HHHHHH 1CJA|A PF09193.5_CholecysA-Rec_N_seed 5 50 !Q:0,1|3,3|5,5|12,12|16,18|20,21|27,28|31,34|36,36|38,38|48,49 Q:2,2|4,4|6,11|13,15|19,19|22,26|29,30|35,35|37,37|39,47 ??S?T-TTTTTT?SSS?-?B??SSSSS??BS????S-S?SSHHHHHHS?? 1D6G|A PF09194.5_Endonuc-BsobI_seed 4 324 !Q:0,0|6,6|14,15|51,51|60,60|73,74|81,82|150,151|162,164|168,169|172,172|203,203|215,231|243,246|273,275|284,285|302,302|309,309|323,323 Q:1,5|7,13|16,50|52,59|61,72|75,80|83,149|152,161|165,167|170,171|173,202|204,214|232,242|247,272|276,283|286,301|303,308|310,322 ?GGGGT?SSGGGGS??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?SSGGGGGG?GGGHHHHHHHTT??HHHHTT??HHHHHHHHHHHHHHTTTTTGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??EEEEETTSTT???EEE??SS?TTGGGGEEEEEEEETTEEEEEEEEEEETTT-TEEEEEEEEES????????----?????GGGEEEEEEEE????HHHHHHHHHHHHHHHHHHHHHHHHTT???EEEEEESS??HHHHHHHHHHHHHTSS?EEEETT?HHHHHHHHHHHHT? 1DC1|A PF09195.6_Endonuc-BglII_seed 20 341 !Q:8,8|10,10|24,25|30,31|34,36|42,42|45,46|63,63|68,112|117,136|138,138|140,140|151,151|164,166|178,186|194,195|197,197|203,203|209,209|220,226|235,235|241,305|311,313|325,325|327,327|329,329|333,333 Q:0,7|9,9|11,23|26,29|32,33|37,41|43,44|47,62|64,67|113,116|137,137|139,139|141,150|152,163|167,177|187,193|196,196|198,202|204,208|210,219|227,234|236,240|306,310|314,324|326,326|328,328|330,332|334,340 THHHHHHH-H?HHHHHHHHHHHHH??GGGG??EE???GGGTT?EE??HHHHHHHHHHHHHHTT?EEEE---------------------------------------------EEEE--------------------E?S?HHHHHHHTTS?HHHHHHHHHHTT???EEEEEEEEEEE---------TTEEEEE??S?HHHHH-HHHHT-HHHHHHHTTS------?SEEEEEEE?HHHHT-----------------------------------------------------------------TSSSS???HHHHHHHHHTT?T-T?SSS?EEEEEEE 3BAM|A PF09196.5_DUF1953_seed 2 66 !Q:0,0|5,7|26,26|29,30|35,36|39,39|47,48|57,57|60,60 Q:1,4|8,25|27,28|31,34|37,38|40,46|49,56|58,59|61,65 ?EEEE???TTEEEEEETTTEEEEEES?TT??EEEE??SS?EEEETTT??EEESEEEE?SS?EEEEE 3HJE|A PF09197.5_Rap1-DNA-bind_seed 19 156 !Q:0,2|23,23|25,25|29,30|33,60|64,66|69,74|82,102|108,109|112,112|128,129|145,151|153,155 Q:3,22|24,24|26,28|31,32|61,63|67,68|75,81|103,107|110,111|113,127|130,144|152,152 ???HHHHHHHHHHHHHHHHHHHH?B?TTT??BS????????????????????????????TTS???TT??????HHHHHHH---------------------HHHST--TS?HHHHHHHHHHTHHHH?-HHHHHHHHHHHHHTT???????S??? 4GFB|A PF09198.5_T4-Gluco-transf_seed 2 38 !Q:0,1|10,12|34,35 Q:2,9|13,33|36,37 ??EEEEESSS???SSSSHHHHHHHHHHHHHHTTT??EE 1IXY|A PF09199.5_DUF1954_seed 21 90 !Q:9,10|21,26|35,35|40,40|46,46|54,54|56,56|60,60|68,73|76,77|83,84|88,89 Q:0,8|11,20|27,34|36,39|41,45|47,53|55,55|57,59|61,67|74,75|78,82|85,87 HHHHHHTTS??EEEEEEEEEE????--SSSEEEEE?SSSS?EEEEE?TTHHHHS?S-EEE-EEEEEEE????-?SS??SSEEE??EEE?? 2RDH|A PF09200.5_Monellin_seed 2 43 !Q:0,1|29,30|38,42 Q:2,28|31,37 ??SSEEEEEEEEEETTEEEEEEEEEETTT??EEEEEEE????? 3MON|A PF09201.5_SRX_seed 5 157 !Q:0,2|8,8|11,11|22,25|40,42|48,48|55,56|62,73|94,96|133,134|138,140|155,156 Q:3,7|9,10|12,21|26,39|43,47|49,54|57,61|74,93|97,132|135,137|141,154 ???EEEEE?TT?BEEEEEETTS????HHHHHHHHHHHHHS???GGGEE?SGGGTT??EEEEE??-?????????EEEEEEEETTEEEEEEEESS-??HHHHHHHHHHHHHHHHHHHHTTHHHHHHHHTSSSTT??TTS???TTTTTHHHHHHHHT?? 1NRJ|A PF09202.6_Rio2_N_seed 29 91 !Q:3,4|21,21|25,25|32,42|45,45|59,60|63,63|66,68|74,74|87,87 Q:0,2|5,20|22,24|26,31|43,44|46,58|61,62|64,65|69,73|75,86|88,90 GGG??HHHHHHHHHHHHHTTT?SSB?HHHHHH???????????HH-HHHHHHHTTSEEE--EE?SS?--EEEEE?HHHHHHHHHHHH-HHT 1TQP|A PF09203.6_MspA_seed 19 253 !Q:3,3|5,8|22,23|26,30|33,33|46,72|81,82|94,94|108,116|119,120|124,124|137,139|142,142|147,162|169,172|180,181|191,207|218,218|223,224|238,238|240,242|247,249|252,252 Q:0,2|4,4|9,21|24,25|31,32|34,45|73,80|83,93|95,107|117,118|121,123|125,136|140,141|143,146|163,168|173,179|182,190|208,217|219,222|225,237|239,239|243,246|250,251 TTS?E----EEEEEEEEEEEEE??TT??---TT?EEEEEEEEEEEE---------------------------EESTTGGG-?EEEEEEEEEEE?SEEEEEEEEEEEE-----????EE--EEE?TTSTTTTTTSEE???SS?EEEE----------------EEEEEE????EEEEEEE--EEEESSEEE-----------------EEEEEEEEEE?SEES??EEEEEEEEEETTS?E---EEEE???EE? 1UUN|A PF09204.5_Colicin_immun_seed 10 93 !Q:0,1|18,18|28,31|40,40|43,44|62,63|67,69|71,72|74,74|76,76 Q:2,17|19,27|32,39|41,42|45,61|64,66|70,70|73,73|75,75|77,92 ??TTHHHHHHHHHHTTSS?HHHHHHHHH----HHHHHHTT?SS??HHHHHHHHHHHHHHHTB??STT-??T--T?B?HHHHHHHHHHHHHHTT 1V74|B PF09205.5_DUF1955_seed 4 162 !Q:0,0|16,16|32,32|47,48|64,64|68,68|70,70|83,85|100,100|112,117|119,119|135,135|151,151|161,161 Q:1,15|17,31|33,46|49,63|65,67|69,69|71,82|86,99|101,111|118,118|120,134|136,150|152,160 ?HHHHHHHHHHHHHTT?HHHHHHHHHHHHHHS?HHHHTHHHHHHHHH??HHHHHHHHHHHGGGS?GGG?S?THHHHHHHHHTT???HHHHHHHHHHHHTT?HHHHHHHHHHH??-???S?HHHHHHHHHHHHHTT?HHHHHHHHHHHHHTT?HHHHHHHHT? 1WY6|A PF09206.6_ArabFuran-catal_seed 7 441 !Q:9,10|20,20|25,26|28,29|38,39|44,51|55,55|58,62|65,65|77,77|84,85|87,120|124,126|130,132|134,134|137,141|147,172|174,174|182,186|200,200|204,204|209,209|211,211|214,216|219,220|228,228|232,235|239,240|246,246|251,253|255,261|264,264|270,271|273,275|278,278|280,282|286,301|307,307|310,310|318,320|323,323|327,331|343,346|369,370|378,379|381,389|396,396|399,404|416,420|435,435|439,440 Q:0,8|11,19|21,24|27,27|30,37|40,43|52,54|56,57|63,64|66,76|78,83|86,86|121,123|127,129|133,133|135,136|142,146|173,173|175,181|187,199|201,203|205,208|210,210|212,213|217,218|221,227|229,231|236,238|241,245|247,250|254,254|262,263|265,269|272,272|276,277|279,279|283,285|302,306|308,309|311,317|321,322|324,326|332,342|347,368|371,377|380,380|390,395|397,398|405,415|421,434|436,438 HHHHHHHTT??EEEEEESSB?SSTT??S??EEEEETTT??EEEE-------?BSS-TT----?BB?HHHHHHHTTTS?EEEEEE??T----------------------------------TSS???EEE???S-SS??---SSGGG?------------------------?B?EESSSEE-----EEETTEEEEEEEE?TTB?EEES-S?SS???BT??EEEEEEE?TTS?--?SSS??EEEEE?TTSS???T-------TS?EEEEE--E???SS?B--?STT??--------------EEEEE?SS?EESSSSS---SB?TTS?????SSEEEEEEEET----TEEEEEEEETTEEEEEEEEEES??SSTTSSS??B-------??EEEESS?TT??????EEEEEEEEESS--???HHHHHHHHHHHHHH?EEE?? 2D43|A PF09207.6_Yeast-kill-tox_seed 2 87 !Q:0,2|10,10|15,16|18,18|20,21|25,25|28,29|32,33|38,39|45,45|57,57|59,59|66,66|73,75|78,80|85,86 Q:3,9|11,14|17,17|19,19|22,24|26,27|30,31|34,37|40,44|46,56|58,58|60,65|67,72|76,77|81,84 ???EEEESSS?TTTS??B?S??TTS?EE??SS??EEEE??TTTTS?EEEEEESSTTS?S?EEEEEE?SSEEEE???SS???EEEE?? 1WKT|A PF09208.5_Endonuc-MspI_seed 3 282 !Q:0,1|10,15|23,23|26,26|65,70|82,85|97,102|108,108|110,111|122,122|137,138|144,144|154,155|159,159|177,177|188,192|208,208|211,213|215,215|219,219|256,256|259,259|269,269|275,276|281,281 Q:2,9|16,22|24,25|27,64|71,81|86,96|103,107|109,109|112,121|123,136|139,143|145,153|156,158|160,176|178,187|193,207|209,210|214,214|216,218|220,255|257,258|260,268|270,274|277,280 ??HHHHHHHH------HTTGGGS?TT?HHHHHHHHHHHHHHHHHHHTSSHHHHHHHTSTTSHHHH------HHHHHHHHHTT??--GGGEEEEEEEE??????BTTBS?S??EEEEEEETTS?EEEEEEEEEEESSS??EEEEE?HHHHHHHHT??TTH-HHHHHHHHHHHTSSTTS?HHHHHHHHHH-----HGGGHHHHHHHHHHS?SS???S?TTS?SEEEEEEEETTEEEEEEEEEHHHHHHHHHHHTTSTT?GG-GGTSSEEEE?TTSSS??EEEE? 1YFI|A PF09209.6_DUF1956_seed 57 144 !Q:15,16|21,24|38,39|42,44|49,50|74,81|114,114|116,116|118,119|134,135 Q:0,14|17,20|25,37|40,41|45,48|51,73|82,113|115,115|117,117|120,133|136,143 HHHHHHHHHHHHHHH--TTSG----GGHHHHHHHHHHH--HS?-?HHHH--HHHHHTHHHHHHHHHHHHHHHHT??------TTSHHHHHHHHHHHHHHHHHHHTHHHHHHHHT?S-S??HHHHHHHHHHHHHH--HHHHHHHH 1T33|A PF09210.6_DUF1957_seed 57 126 !Q:18,20|22,24|29,30|51,53|56,56|81,84|87,101|113,113|115,115|118,119|122,123 Q:0,17|21,21|25,28|31,50|54,55|57,80|85,86|102,112|114,114|116,117|120,121|124,125 HHHHHHHHHHHHHHHHTT---T???HHHH--HHHHHHHHHHHHTTBGGGTS???TT?HHHHHHHHHHHHHHHHHHHHHHHH----TT??--------?----HHHHHHHHHHS?S?TT??GG--GG 3N98|A PF09211.5_DUF1958_seed 9 69 !Q:5,5|19,19|21,21|30,31|35,35|42,42|49,49|51,52|58,59|61,63|68,68 Q:0,4|6,18|20,20|22,29|32,34|36,41|43,48|50,50|53,57|60,60|64,67 EEEEE?SEEEEETTEEEEE?S?EEEEEETT??GGG?EEEEET-TEEEEE?S??BSSTT??S?-?EEEE? 1TVF|A PF09212.5_CBM27_seed 2 173 !Q:0,1|9,13|29,29|54,56|59,59|65,65|69,69|86,87|90,92|95,96|113,113|119,119|138,141|144,145|156,157 Q:2,8|14,28|30,53|57,58|60,64|66,68|70,85|88,89|93,94|97,112|114,118|120,137|142,143|146,155|158,172 ??EEEEEEE--???SGGGGGGEEEEEEES?EEEEEEEEEESSGGGSEEEEEEEE???SS?EEEEE-EEE?TTGGGEEEEEEEEEEE??TT???EE??EEEEETTTEEESTTSS?EETTS?EEEEETTEEEEEEEEEEE????TT??EEEEEEEEES??EEEEEEEEEEEEEEE 1OF4|A PF09213.5_M3_seed 2 384 !Q:5,8|22,27|32,33|50,50|58,58|68,68|82,85|88,91|95,95|105,108|111,112|115,117|124,124|127,127|132,132|159,159|168,169|172,172|194,194|198,199|201,202|210,212|224,224|231,232|238,239|243,243|245,245|247,249|252,252|255,255|268,269|272,276|278,278|286,286|290,291|293,293|302,307|311,314|327,327|333,337|340,341|347,347|358,358|383,383 Q:0,4|9,21|28,31|34,49|51,57|59,67|69,81|86,87|92,94|96,104|109,110|113,114|118,123|125,126|128,131|133,158|160,167|170,171|173,193|195,197|200,200|203,209|213,223|225,230|233,237|240,242|244,244|246,246|250,251|253,254|256,267|270,271|277,277|279,285|287,289|292,292|294,301|308,310|315,326|328,332|338,339|342,346|348,357|359,382 SEEEE????TTTSTTHHHHHHH------HSSS??SSTHHHHHHHHHHHHH?TTGGGGG?SEEEEEEEE?EEEGGGTEEEEEE????SS????TTS?EEEEEEEEE????SS??SS???EEEEEE?SS?EEEE?GGGEEEEETTEEEEEEEEEGGGSSTT?EEEEEESS??TT?EEEEEEEEETTEEEEEEEEEE?TTS??B??SEEEEET---TSSGGGGSSST-TTTTTT??GGGTS??EEE?S?T---TS?SS?EEEESTHHHHHH?-SS?????S?EEEEEEE?GGG??S?EEEEEEEE??????TTS????EEEEEEEEEEET-TEEEE--???SS??EEEEE?SSTTEEEEEE?GGGGGGEEEEEEEETTEEEEEESS? 1MKF|A PF09214.6_Prd1-P2_seed 2 560 !Q:0,0|5,5|10,11|19,19|22,24|29,30|34,34|38,38|44,45|56,58|65,66|68,68|75,76|78,78|80,83|87,89|105,105|108,112|115,115|126,127|130,130|153,156|162,162|166,167|172,173|176,176|180,181|183,186|189,189|194,194|199,199|207,207|214,215|238,269|272,278|281,281|286,286|289,289|297,298|319,321|329,330|334,334|336,337|343,345|351,351|359,359|395,395|401,401|415,417|421,422|437,437|439,440|442,443|448,448|455,455|459,459|462,464|479,480|486,487|498,498|504,504|510,515|519,519|521,524|538,539|541,541|544,545|547,547|549,549|557,559 Q:1,4|6,9|12,18|20,21|25,28|31,33|35,37|39,43|46,55|59,64|67,67|69,74|77,77|79,79|84,86|90,104|106,107|113,114|116,125|128,129|131,152|157,161|163,165|168,171|174,175|177,179|182,182|187,188|190,193|195,198|200,206|208,213|216,237|270,271|279,280|282,285|287,288|290,296|299,318|322,328|331,333|335,335|338,342|346,350|352,358|360,394|396,400|402,414|418,420|423,436|438,438|441,441|444,447|449,454|456,458|460,461|465,478|481,485|488,497|499,503|505,509|516,518|520,520|525,537|540,540|542,543|546,546|548,548|550,556 ?EEEE?EEEE??EEEEEEE?SS???BTTT??SSS?BTT?GGGEE??SSEEEEEEEE???TTSEEE??B?BTTBTT??B?S????EEE???SHHHHHHHHHHHTTS?TT?????EE?HHHHHGGGTT??EE?TTSEEETTEEESEEEEEEEESS????EEEEE?TTT??EEEE??EE?TTS??B????EE?BSSS?EEEE?TTTTTSS?SEEEEE??BGGGTEEEEEEEEEEEEEEEEE????????????????????????????????SS???????SS?EEEE?SS?TTSEEEE??EEEEEEEEEEEEEEEEEEEE???EEEEEEE??TTT?B??EEEES???SEEEE?SEEEEEE?SSSEEEEEEESSSSEEEEEEEEETTEEEEEEEEEE?GGGTT?HHHHHHHHHHHHS???TTS??EESSSEEEEHHHHH?S??S??TTTT?EEEETT?TTS?TT???EEEEETTEEEEEEE??SSTTS??EEEEEETTSS?EEEEE?HHHHB?-----SSS?B????EEEEETTEEEEEE??B?TT??B?B?EEEEEEE??? 1N7V|A PF09215.5_Phage-Gp8_seed 10 410 !Q:3,6|23,37|44,44|51,52|54,54|56,56|64,71|90,90|100,101|104,134|136,136|141,141|144,146|149,149|160,160|162,162|165,167|176,177|180,187|195,197|206,207|212,216|218,219|222,224|226,227|231,231|234,235|237,237|240,240|249,249|257,258|265,266|273,273|279,279|282,283|285,295|302,302|309,310|315,315|328,328|331,333|343,343|346,347|353,355|357,358|361,361|364,364|369,369|372,372|377,385|394,396|399,399|404,405|409,409 Q:0,2|7,22|38,43|45,50|53,53|55,55|57,63|72,89|91,99|102,103|135,135|137,140|142,143|147,148|150,159|161,161|163,164|168,175|178,179|188,194|198,205|208,211|217,217|220,221|225,225|228,230|232,233|236,236|238,239|241,248|250,256|259,264|267,272|274,278|280,281|284,284|296,301|303,308|311,314|316,327|329,330|334,342|344,345|348,352|356,356|359,360|362,363|365,368|370,371|373,376|386,393|397,398|400,403|406,408 EEE?---HHHHHHHHHHHHHHBS---------------SSTTSB?EEEEEE??S?S?GGGGSTT????????SHHHHHHHHHHEEEEEEE?GGGEEEEEE??BT-------------------------------T?TTSS?SS???TT?EEEESSSTTT?S?TT-??EEEEEEEE??SS--------EEESSTT???HHHHHHTT??EEES-----S??SS???S??STT?EE??S-SS?EEEEEEEE?HHHHHHH??SSEEEE??HHHHHH?GGGGT?TT??T-----------HHHHTT?HHHHTT??EEEE?EEEETTTSGGGG?SS???EEEEEEEES?BB??SSTTS???B??SS-EE?GGGB?TT?SEEE---------EEEEEEEE???TT?EEEE??EEE? 1PDM|A PF09216.5_Pfg27_seed 2 188 !Q:0,3|5,6|10,10|12,13|50,50|67,71|94,96|124,124|136,136|153,156|175,176|179,187 Q:4,4|7,9|11,11|14,49|51,66|72,93|97,123|125,135|137,152|157,174|177,178 ????S--SSS?S??HHHHHHHHHHHHHHHHHHHHHHHTTTSTTHHHHHHT?HHHHHHHHHHHHHHTT?????HHHHHHHHHHHHHHHHHHHSSS???HHHHHHHHHHHHHHHHHHHHHHHHHHH?SSHHHHHHHHT?HHHHHHHHHHHHHHHT????HHHHHHHHHHHHHHHHHH??TT????????? 1N81|A PF09217.5_EcoRII-N_seed 6 165 !Q:13,14|23,23|25,26|31,31|39,39|43,44|50,50|62,65|74,74|80,82|85,86|92,94|99,99|102,102|108,108|116,117|122,124|131,132|145,148|151,156 Q:0,12|15,22|24,24|27,30|32,38|40,42|45,49|51,61|66,73|75,79|83,84|87,91|95,98|100,101|103,107|109,115|118,121|125,130|133,144|149,150|157,164 HHHTSSEEEEEEE??HHHHTTTS?S??EEEE?HHHHHHH?GGG??SSSSS?EEEEEEEESSS????EEEEEEEE?TTTTT---SS??EEEEE???TTSG-GG?GGGTT?EEEEEEE??TTSS???EEEEEE??SHHHHHHHHHHH????TT?----?EEEEHHHH 1NA6|A PF09218.5_DUF1959_seed 5 117 !Q:10,10|38,38|75,76|78,78|93,93|98,99 Q:0,9|11,37|39,74|77,77|79,92|94,97|100,116 HHHHHTSHHH-HHHTTTTTTTTGGGTHHHHHHHHHHHS?HHHHHHHHHHHHTTHHHHHHHHHHHHTTHHHHTTTS??S?HHHHHHHHHHHHHH-HHTT??HHHHHHHHHHHHHHHHT 1NXH|A PF09220.5_LA-virus_coat_seed 2 436 !Q:0,0|12,13|16,20|24,24|54,54|56,58|64,69|78,78|84,84|98,99|113,117|119,119|140,148|151,151|157,160|163,163|168,168|171,173|176,176|181,183|185,186|189,190|193,193|198,198|202,202|206,206|219,219|221,223|230,231|233,234|236,236|239,239|243,243|246,248|257,257|259,259|264,267|284,284|300,300|303,304|316,317|323,324|326,327|336,336|338,338|356,356|387,387|390,392|414,414|418,420|425,425|429,429|434,434 Q:1,11|14,15|21,23|25,53|55,55|59,63|70,77|79,83|85,97|100,112|118,118|120,139|149,150|152,156|161,162|164,167|169,170|174,175|177,180|184,184|187,188|191,192|194,197|199,201|203,205|207,218|220,220|224,229|232,232|235,235|237,238|240,242|244,245|249,256|258,258|260,263|268,283|285,299|301,302|305,315|318,322|325,325|328,335|337,337|339,355|357,386|388,389|393,413|415,417|421,424|426,428|430,433|435,435 ?HHHHTTTTTTS??EE?????SSS?EEEEEEEEEEEEETTEEEEEEEEEEEEEE?B???EEEEE??????TTSBGGGB?SSSSB?HHHHHHHHHHTSS??HHHHHHHHHHTSS?????B?HHHHHHHHHHHHHHHHHHTT?????????EE?SSEEE????SS?TTTS?SS???SS?TTTS???B??EE??SS?SSSS?EEE?TTS?HHHHHHHHHHTS?B???SSBGGG??B??S?SB?EEE?SS???TTHHHHHT?S?TTTS????HHHHHHHHHHHHHHTT?HHHHHHHHHHHHHSS?EE??SSTGGGGTTTS??EEEEE??B??TTSSTTTT?S?EEEEEHHHHHHHHHHHH?THHHHHHHHHHHHHHHHHHHHHHHHTTTSS?SS???TTTSGGGSHHHHHHHHHHHHH?SEE???SSSS?EEE?GGGS?S 1M1C|A PF09221.5_Bacteriocin_IId_seed 17 70 !Q:4,6|21,22|34,34|41,41|49,49|62,62|69,69 Q:0,3|7,20|23,33|35,40|42,48|50,61|63,68 HHHH???HHHHHHHHHHHHTT??HHHHHHHHHHH?HHHHHH-HHHTTTS?HHHHHHHHHHHH?HHHHHH? 1O82|A PF09222.5_Fim-adh_lectin_seed 2 171 !Q:3,3|5,5|12,12|22,22|26,26|30,32|35,35|50,50|59,59|61,61|95,96|100,100|109,111|128,128|130,131|139,140|151,151|154,156|160,161|168,169 Q:0,2|4,4|6,11|13,21|23,25|27,29|33,34|36,49|51,58|60,60|62,94|97,99|101,108|112,127|129,129|132,138|141,150|152,153|157,159|162,167|170,170 EEE?S?SEEEES?TTEEEEEEE?TTS?SEE???TT?SEEEEEEEEEEETT?EEEEEEEE?S?EEEEETTEEEEESSSSEEEEEEEESSSGGGEEE??SSS?EEEEEEEE??-SSEEEEEEEEEEEEEE?S??SSEEEEE??EEEEEEEEEE?TT???TTS??EEEEEE??E 1ZPL|A PF09223.6_YodA_seed 33 189 !Q:9,11|15,19|24,24|50,50|52,52|54,55|68,69|71,72|77,78|87,88|91,91|97,97|107,107|111,111|120,122|125,127|129,131|140,141|144,146|157,157|164,165|167,169|176,177|187,188 Q:0,8|12,14|20,23|25,49|51,51|53,53|56,67|70,70|73,76|79,86|89,90|92,96|98,106|108,110|112,119|123,124|128,128|132,139|142,143|147,156|158,163|166,166|170,175|178,186 HHHHHHTTT???GGG?????GGGG?EEEEESHHHHHTTTTHHHHHHHHTT?T-T??HHHHHHHHHHHH??S??EEEE--ETTEEEEE?-SS?EEEEE?EEEEEEEEE?TTS?EEEEEEEE???SS?-?S--?SEEEEESS??SS???SSEEEEEESS?HHHHHH??S???EEEETT??HHHHHHHHT?? 1S7D|A PF09224.6_DUF1961_seed 3 219 !Q:3,3|10,12|20,20|30,30|39,44|50,51|56,59|61,61|75,75|91,92|95,95|99,102|104,104|132,132|150,154|158,159|161,161|187,188|195,197|209,209 Q:0,2|4,9|13,19|21,29|31,38|45,49|52,55|60,60|62,74|76,90|93,94|96,98|103,103|105,131|133,149|155,157|160,160|162,186|189,194|198,208|210,218 EEE-EEEEEE???SGGGGTT?EEEESEEEE?GGGSEEEE------ESSTT??EEEE????B?SSEEEEEEEEEEE?SEEEEEEEEEEETTS??TT?TTS????S?THHHHSSSEEEEEEEEEEESSHHHHTS?EEEEEEETTTEEEEEEE?????GGG??S?EEEEEEEETTEEEEEETTEEEEEEE??SSSSSS???SBEEEEEEETT?EEEEEEEEE 1OQ1|A PF09225.5_Endonuc-PvuII_seed 3 155 !Q:0,0|25,25|27,27|45,45|48,54|58,58|62,62|74,74|78,80|84,84|95,95|113,113|134,135|137,137|139,140|154,154 Q:1,24|26,26|28,44|46,47|55,57|59,61|63,73|75,77|81,83|85,94|96,112|114,133|136,136|138,138|141,153 ?HHHHHHHHHHHHHHHHHHHHHHTT?S?TTSTTHHHHHHHHHHHT?EE???????SEE?TTS?EEEEEEEETTT?SEE???TTB?HHHHHHHTTS?EEEEEEETTEEEEEEEE?HHHHHHHHHHHHHHHHHTSS??B?S??EEHHHHHHHSEEE? 2PVI|A PF09226.6_Endonuc-HincII_seed 2 257 !Q:0,1|16,16|20,21|25,27|65,65|68,69|80,80|88,90|97,97|102,106|109,109|111,111|120,120|134,138|158,159|192,192|196,197|208,209|213,218|220,220|255,256 Q:2,15|17,19|22,24|28,64|66,67|70,79|81,87|91,96|98,101|107,108|110,110|112,119|121,133|139,157|160,191|193,195|198,207|210,212|219,219|221,254 ??SGGGHHHHHHHHBT?EEE??TTS???GGGSSHHHHHHHHHHHHHHSTTTEEEHHHHHHHHHHT?TT??SHHHHHGGGS?HHHHHHH???HHHHHH?BTTB?????TT?S?SEEEESSS?EEEEEEEEEETTS?????EEEEHHHHHHHHHHHHHHT??SSEEEEEEEEEEEEETTEEEEEEEEEEEGGGS?GGG??EESTBTTEEE??GGG??????S?HHHHHHHHHHHHHHHHHHHHHHHHHHHTGGGTTT?? 2GIH|A PF09227.5_DUF1962_seed 3 70 !Q:0,3|6,7|11,12|15,20|23,24|30,30|34,34|54,54|58,59|69,69 Q:4,5|8,10|13,14|21,22|25,29|31,33|35,53|55,57|60,68 ????TT??TTB??TT------SB??GGGTT?EEE?TTSSEEEEEETTEEEEEEE?SSS??EEETTEEEE? 1UOY|A PF09228.5_Prok-TraM_seed 14 107 !Q:0,23|29,29|64,64|68,68|101,101|103,106 Q:24,28|30,63|65,67|69,100|102,102 ??????????------????????TTTTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?TTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?S???? 1RFY|A PF09229.6_Aha1_N_seed 69 237 !Q:0,0|3,3|18,23|27,28|34,61|65,67|74,75|79,79|81,81|85,86|88,88|90,91|93,95|107,125|127,128|132,143|145,145|161,165|169,172|175,186|190,190|192,193|196,196|199,202|215,216|233,234|236,236 Q:1,2|4,17|24,26|29,33|62,64|68,73|76,78|80,80|82,84|87,87|89,89|92,92|96,106|126,126|129,131|144,144|146,160|166,168|173,174|187,189|191,191|194,195|197,198|203,214|217,232|235,235 ?EE?HHHHHHHHHHHHTT-----?EES?-SSSSS----------------------------EEE---EEEEEE--EEE-E?EEB??S-S??B???EEEEEEEEEEE-------------------E??SSS------------S?EEEEEEEEEEEEETT-?--?TTT???-EE------------EEE-T??TT?TT----HHHHHHHHTHHH--HHHHHHHHHHHHHHHH--S? 3N72|A PF09230.5_DFF40_seed 9 311 !Q:12,14|30,31|34,35|40,40|48,49|52,53|82,87|116,116|119,119|121,121|124,177|179,179|182,182|185,186|189,192|197,198|200,200|203,204|207,207|211,211|228,228|244,261|264,264|266,266|284,284|288,290|292,304|310,310 Q:0,11|15,29|32,33|36,39|41,47|50,51|54,81|88,115|117,118|120,120|122,123|178,178|180,181|183,184|187,188|193,196|199,199|201,202|205,206|208,210|212,227|229,243|262,263|265,265|267,283|285,287|291,291|305,309 TTHHHHHHHHHS???HHHHHHHHHHHHHHS??TT??BTTT?TTTTTTS-?TT??BHHHHHHHHHHHHHHHHHHHHHTTGGGS-----?TTTHHHHHHHHHHHHHHHHHTGGGGGGG?SS-S?TT------------------------------------------------------T?SS?TT??EE????TTSS--S?TT??EE?GGG?HHHHHHTTTSEEEESS?TTTTHHHHHHHHHHH------------------SS?B?HHHHHHHHHSTTTEEEE?GGG???S?????------??TTTSB? 1V0D|A PF09231.5_RDV-p3_seed 2 967 !Q:0,4|6,6|9,10|19,21|30,31|35,36|39,39|48,48|50,50|57,57|61,61|65,65|91,92|107,107|115,115|145,145|148,148|151,157|162,163|175,175|195,195|207,208|214,214|224,225|232,239|246,246|261,262|268,269|283,284|287,289|298,299|316,316|326,328|349,349|354,354|375,375|389,390|393,393|399,400|402,403|412,413|416,416|430,431|437,437|441,441|448,450|462,464|468,469|471,471|483,484|486,488|490,491|493,493|501,502|517,517|520,521|524,525|569,574|578,578|588,588|600,602|605,612|640,640|646,646|665,667|678,680|682,682|693,695|697,699|728,728|734,736|739,739|742,743|752,753|764,764|775,775|779,779|783,783|796,799|805,805|808,810|815,817|819,820|827,829|840,840|842,843|846,853|867,867|870,872|883,883|887,893|895,895|907,909|913,914|918,920|934,934|943,944|947,951|953,953|957,957|960,966 Q:5,5|7,8|11,18|22,29|32,34|37,38|40,47|49,49|51,56|58,60|62,64|66,90|93,106|108,114|116,144|146,147|149,150|158,161|164,174|176,194|196,206|209,213|215,223|226,231|240,245|247,260|263,267|270,282|285,286|290,297|300,315|317,325|329,348|350,353|355,374|376,388|391,392|394,398|401,401|404,411|414,415|417,429|432,436|438,440|442,447|451,461|465,467|470,470|472,482|485,485|489,489|492,492|494,500|503,516|518,519|522,523|526,568|575,577|579,587|589,599|603,604|613,639|641,645|647,664|668,677|681,681|683,692|696,696|700,727|729,733|737,738|740,741|744,751|754,763|765,774|776,778|780,782|784,795|800,804|806,807|811,814|818,818|821,826|830,839|841,841|844,845|854,866|868,869|873,882|884,886|894,894|896,906|910,912|915,917|921,933|935,942|945,946|952,952|954,956|958,959 ?????S?SS??EEEEGGGS???EEEEEEEE??SSS??SS?EEEEEEEE?S?TTHHHH?TTS?TTT?HHHHHHHHHHHHHHHHHTTTEEEEE??EEEEEETTEEEEEE?GGGSGGG?HHHHHTTSSSHHHHHHHHHHHHHHSEEEE?SS?SS???????TTTS??GGGEEEEEESS?HHHHHHHHHHHHHHHHHEE?HHHHHHHHHHT??TTEEE?HHHHHHHHS??TTEEEE????????GGGGGG?HHHHHHHHHHHHHH??EEEEE??HHHHHHHHHHHHT??TT???HHHHHTTS??HHHHHHHHHHHHHTTT?TTTEEEEES???TTGGGSHHHHHHHHHHTTTS?GGGB?HHHHHHHHHHHHHHHHHHTS?HHHHHHHHHTTSS??TT?TTTSS??S??HHHHHHHT??TT?HHHHHHHHHHTTT??HHHHT?EEE?GGGSTT???EEGGGTTTSTT???GGG??B?GGGHHHHHHHT??S???B??S?EETTTEE??HHHHHHHHHHHHTT-SS??SS??THHHHHHHHHHHHHHHHHHHGGGGHHHHHHHHTTHHHHHSBSS??????TTS?GGGSEEEEE?GGGHHHHHHHB???SS????????BTTTTHHHHHHHHHHHHHHHHHHHHSS?HHHHS?HHHHHHHHHHHHHHHHTS???HHHHTBSSSS???B?HHHHHHHHHS???S???HHHHHHHHHHHHHHHHHHHGGGGSSEES?EEEES???EE?TT??SSEEEESS??GGGEEEEEEE?SHHHHHHHHT?EEE?SSS?EEEHHHHHHHTS????HHHHH?EE---TTEE???S??EEEEEE???EEEEEEEEEE?S??SS????????HHHHHHHHHHSTT?SS???EEEEEEEEEE?TTS???????S?HHHHHHHHGGG???SEE??GGG???EEESSHHHHHHHS?EEEEEESS??EE?????B?EEE?SS??????? 1UF2|A PF09232.5_Caenor_Her-1_seed 2 132 !Q:2,2|17,20|23,24|26,26|45,45|49,51|65,65|82,82|86,86|101,101|119,120|125,125|130,131 Q:0,1|3,16|21,22|25,25|27,44|46,48|52,64|66,81|83,85|87,100|102,118|121,124|126,129 HS?GGGHHHHHHHHHHT????TT??S?TTHHHHHHHHHHHHHTSS?GGG???GGGGGGGGGGGGS?SHHHHHHHHHHHHHTT?TTS?HHHHHHHHHHHTTT?HHHHHHHHHHHHHHHTT??GGGS?GGGT?? 1SZH|A PF09233.6_Endonuc-EcoRV_seed 3 252 !Q:13,14|24,24|28,29|56,56|60,61|66,66|68,68|74,74|77,77|96,99|101,102|114,115|123,123|140,143|149,149|151,151|159,160|191,192|194,194|202,203|205,205|208,209|220,226|236,236|249,249|251,251 Q:0,12|15,23|25,27|30,55|57,59|62,65|67,67|69,73|75,76|78,95|100,100|103,113|116,122|124,139|144,148|150,150|152,158|161,190|193,193|195,201|204,204|206,207|210,219|227,235|237,248|250,250 HHHHHHHHHHHHH??EEEEEETTS?EEE??SSHHHHHHHHHHHHHHHHHHHHHHTT?EEE??SSTT?B?SEEEE?TT?TTSEEEEEEEEEEESSTT??--B??EEEESSSTTTS--TTTTBSS?GGGEEEEEEEEEEEEE????GGGGS?B?GGGGGGS??SEEEEEEEEEEHHHHEEEEEEETTTTEEEE??B?HHHHHHT??S?SS--HHHHHHHHHS??-----SSHHHHTTS?SSHHHHHHHHHT-T? 1RVA|A PF09234.5_DUF1963_seed 34 371 !Q:0,0|5,9|13,14|16,18|20,35|39,49|51,51|63,71|75,78|81,84|91,92|95,95|101,102|105,105|108,109|111,112|122,125|127,131|135,138|142,146|149,152|155,155|157,157|163,163|168,175|177,179|192,192|201,205|219,230|232,233|235,237|240,241|245,248|251,280|282,282|287,312|315,316|322,323|326,326|328,333|339,340|344,345|352,352|360,361|364,364|370,370 Q:1,4|10,12|15,15|19,19|36,38|50,50|52,62|72,74|79,80|85,90|93,94|96,100|103,104|106,107|110,110|113,121|126,126|132,134|139,141|147,148|153,154|156,156|158,162|164,167|176,176|180,191|193,200|206,218|231,231|234,234|238,239|242,244|249,250|281,281|283,286|313,314|317,321|324,325|327,327|334,338|341,343|346,351|353,359|362,363|365,369 ?EESS?-???BTT--S???B--------------?-TTS---------?-B?EEEEEEEGGGS?-----?-?TTS--?-SS---?EEEEEE?-SS-SSSTT??SS?TT??S--SEEEEEESS????G-----GGB????TTS???--SS?--?SB?S?EEEEE-EEEE--------E???TTSTTHHHHHTS?HHHHHHTT-----GGGHHHHHHHHHH------------T??S---SE--EES????SS----------------------------??S?TTTT--------------------------TT??EEEEE--EE?B------GGGTB??TTT-?EEEEEE?HHHHHTT??TT?EEEEE? 1PV5|A PF09235.5_Ste50p-SAM_seed 3 76 !Q:0,1|5,6|21,21|30,30|35,37|56,56|73,74 Q:2,4|7,20|22,29|31,34|38,55|57,72|75,75 ??TTT??HHHHHHHHHHHHSS?TTSTHHHH-HHHS???GGGHHHHHHHHHHHTSSS?HHHHHHHHHHHHHHHH??S 1UQV|A PF09236.5_AHSP_seed 3 89 !Q:20,23|26,28|51,52|54,54|88,88 Q:0,19|24,25|29,50|53,53|55,87 HHHHHHHHHHHHHHHHHHHH????SS???HHHHHHHHHHHHHHHHHHHHHS??S?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS? 1W09|A PF09237.6_GAGA_seed 3 54 !Q:0,5|7,7|10,14|22,23|26,26|30,31|49,49|51,53 Q:6,6|8,9|15,21|24,25|27,29|32,48|50,50 ??????S?SS?????TTTTTTS??EE?TTT??EESSHHHHHHHHHHHTS?S??? 1YUJ|A PF09238.5_IL4Ra_N_seed 7 100 !Q:0,0|10,10|24,26|39,39|43,45|47,47|50,51|56,58|68,68|70,72|75,76|94,94 Q:1,9|11,23|27,38|40,42|46,46|48,49|52,55|59,67|69,69|73,74|77,93|95,99 ?EEEEEEEEE?SSSEEEEEEEESS???HHHHEEEEEEES-SSS???E-EE??EESS---SSEEEEEEE?S???TT??EEEEEEETTEEEEEEEE?GGGSB 3BPN|B PF09239.6_Topo-VIb_trans_seed 36 182 !Q:0,2|6,10|21,23|26,27|32,34|36,38|45,45|60,62|66,70|79,81|83,84|87,87|92,92|96,97|100,101|106,109|112,112|115,116|119,120|127,127|130,131|141,147 Q:3,5|11,20|24,25|28,31|35,35|39,44|46,59|63,65|71,78|82,82|85,86|88,91|93,95|98,99|102,105|110,111|113,114|117,118|121,126|128,129|132,140|148,181 ??-STT?????HHHHHHHHHH---HS??SEEE?-?B???EEETTE-EEEEEEEEEESSSS?--SSS--???EEEEETTB???S??TT?HHHH-HHH--HS??TTTT????SS-SS??SS??EEEEEE?SS??BSSSSSSSB?----??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTHH 1MX0|A PF09240.5_IL6Ra-bind_seed 23 132 !Q:1,1|3,4|13,23|33,42|49,49|52,52|55,55|58,63|69,81|87,90|93,95|99,105|113,121|127,127 Q:0,0|2,2|5,12|24,32|43,48|50,51|53,54|56,57|64,68|82,86|91,92|96,98|106,112|122,126|128,131 S?E--EEEEEEET-----------TTEEEEEEE??????????EEEEEE?TT?SS?EE-----?SEEEE??-??--------EEEEE????TT--?SSS------?EEEEEEE?????????EEEEE?GGGS 1F6F|B PF09241.5_Herp-Cyclin_seed 3 106 !Q:0,2|16,17|45,45|62,63|66,67|81,82|100,101|105,105 Q:3,15|18,44|46,61|64,65|68,80|83,99|102,104 ???GGGSHHHHHHHTT??GGGHHHHHHHHHHHHHHHTTSGGGTTS?HHHHHHHHHHHHHHTT??SS??THHHHHHHHHHHT??HHHHHHHHHHHHHHHHT??GGG? 2F2C|A PF09242.6_FCSD-flav_bind_seed 53 81 !Q:0,5|16,17|31,31|40,40|43,47|49,49|52,52|55,56|80,80 Q:6,15|18,30|32,39|41,42|48,48|50,51|53,54|57,79 ???-??EEEEEEEEEE--TTEEEEEEEEEEE?TTSSSEEE?TT---??E-ES?TT??HHHHHHHHHHHHHHHHHHHHHHH? 3VRD|B PF09244.5_DUF1964_seed 3 70 !Q:21,21|23,24|26,26|33,33|38,38|42,43|45,46|62,62|67,69 Q:0,20|22,22|25,25|27,32|34,37|39,41|44,44|47,61|63,66 GGGSEEEEEEETTTEEEEEEE?S--S?EEEEEE?GGGG?STT??S??EEEEEEETTEEEEES?TTTS??? 2GDV|A PF09245.5_MA-Mit_seed 2 214 !Q:0,3|8,14|16,16|19,22|24,25|36,37|96,96|125,125|149,153|157,157|176,176|197,197|199,199|204,204|212,213 Q:4,7|15,15|17,18|23,23|26,35|38,95|97,124|126,148|154,156|158,175|177,196|198,198|200,203|205,211 ????SSSS???????S?TT????S??HHHHHHHHTT??SGGGHHHHHHHHHHHHHHHHHHHHHHHHHTTSTTHHHHHHHHHHHHHHHHHHHHHSTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHHHHHHHTTT?????TTS?HHHHHHHHHTTTSHHHHH?HHHHHHHHHHHHHHHHHHTT?S?GGGT?HHHHHHS?? 1R5I|D PF09246.5_PHAT_seed 4 112 !Q:13,14|17,18|20,20|35,38|41,42|44,44|48,48|67,67|71,71|74,74|91,91|111,111 Q:0,12|15,16|19,19|21,34|39,40|43,43|45,47|49,66|68,70|72,73|75,90|92,110 HHHHHHHHHHHHH--TT?-S?HHHHHHHHHTTTTS????TT??S?GGG?HHHHHHHHHHHHHHHHHT?TTG-GG?HHHHHHHHHHHHHHHT?GGGGGGHHHHHHHHHHHHT? 1OXJ|A PF09247.6_TBP-binding_seed 8 82 !Q:0,5|8,12|14,16|23,23|31,32|35,37|41,41|44,45|55,55|68,81 Q:6,7|13,13|17,22|24,30|33,34|38,40|42,43|46,54|56,67 ---???SS?----S???TTHHHH?EETTTEE??SS???SSS?SS??TTTHHHHTT?TTTTHHHHHHTS--------?????? 1TBA|A PF09248.5_DUF1965_seed 7 77 !Q:0,2|6,6|16,17|20,20|24,24|51,63|67,68|70,71|73,75 Q:3,5|7,15|18,19|21,23|25,50|64,66|69,69|72,72|76,76 ???GGG?EEEEEEEEE??SS?GGG?EEEEEEETTEEESSHHHHHHHHTSTT?????????---?GGG??S??S???T 1W7C|A PF09249.6_tRNA_NucTransf2_seed 41 133 !Q:14,17|22,22|24,25|48,48|50,51|53,53|61,65|72,86|89,89|93,93|96,96|99,99|105,106|122,122|125,126|132,132 Q:0,13|18,21|23,23|26,47|49,49|52,52|54,60|66,71|87,88|90,92|94,95|97,98|100,104|107,121|123,124|127,131 HHHHHHHHHHHHTT????STTT?S??HHHHHHHHHHHSSHHHHHHHHT-T??T-TEEEETT-----TTEEEE--------------?SS?EEE?TT?TT?BTTTT??HHHHHHHHHHHHHHH-HS??GGGSS? 2DRB|A PF09250.6_Prim-Pol_seed 98 457 !Q:5,5|8,8|10,12|16,36|44,75|86,88|100,100|103,148|150,150|157,167|179,179|182,212|219,228|237,237|241,247|251,255|259,276|283,283|286,289|292,292|305,328|331,336|339,339|342,342|344,355|357,358|360,367|369,375|377,377|384,385|389,389|396,396|400,400|405,410|412,413|418,422|438,438|443,453 Q:0,4|6,7|9,9|13,15|37,43|76,85|89,99|101,102|149,149|151,156|168,178|180,181|213,218|229,236|238,240|248,250|256,258|277,282|284,285|290,291|293,304|329,330|337,338|340,341|343,343|356,356|359,359|368,368|376,376|378,383|386,388|390,395|397,399|401,404|411,411|414,417|423,437|439,442|454,456 HHHHH-HT-T???EEE--------------------?TTTSSBS--------------------------------STTGGGGGTS???HHHHHHHHHHH-HT----------------------------------------------T?EEEEES-----------SGGGEEEEEES?HH-------------------------------HHHHHH?---------HHHHHHHH-HHS?------EEE?----TTS-----------------?EEEEEE?SS??--SS?EEEEEEETTEEE------------------------EE------EE?TT?E------------E--E?-------T-------T?EEEGGG??STT?TTTTSS?EEE?EESS??????B??HHHH-----HHHHHHHHGGGTEEE?HHHH-----------HHH 1RO0|A PF09251.5_PhageP22-tail_seed 6 551 !Q:8,9|16,16|26,26|33,33|35,35|38,39|46,46|49,51|56,56|58,58|61,61|69,71|74,74|79,79|83,83|85,87|91,92|94,94|97,98|100,102|110,110|113,113|119,121|136,136|142,145|153,153|156,156|161,161|173,173|176,176|181,181|187,187|190,190|196,197|201,201|203,203|205,205|210,210|215,215|218,218|227,227|232,233|238,238|243,243|246,246|251,252|260,262|265,265|275,275|278,278|283,294|298,299|304,304|307,312|321,322|325,325|334,334|344,344|347,347|356,356|366,367|370,371|374,374|379,379|382,382|390,401|415,417|427,428|431,432|434,439|449,450|454,454|458,459|472,474|499,500|504,506|510,512|516,517|539,539|543,543 Q:0,7|10,15|17,25|27,32|34,34|36,37|40,45|47,48|52,55|57,57|59,60|62,68|72,73|75,78|80,82|84,84|88,90|93,93|95,96|99,99|103,109|111,112|114,118|122,135|137,141|146,152|154,155|157,160|162,172|174,175|177,180|182,186|188,189|191,195|198,200|202,202|204,204|206,209|211,214|216,217|219,226|228,231|234,237|239,242|244,245|247,250|253,259|263,264|266,274|276,277|279,282|295,297|300,303|305,306|313,320|323,324|326,333|335,343|345,346|348,355|357,365|368,369|372,373|375,378|380,381|383,389|402,414|418,426|429,430|433,433|440,448|451,453|455,457|460,471|475,498|501,503|507,509|513,515|518,538|540,542|544,550 HHHHHHHS??EEEGGG?SSHHHHHHH?SSEEEE?S?EE??TTEEEE?TT???EEEE?S?EE?SEEEEEE???TT?EEES?EEE?S???EEB??B?TT??B???HHHHHTT?EE?SSSSB???HHHHHHSTTHHHHS?GGGSS????EEEEEES?BS?EEES?EEEEEEEEEES?BS?EEES?EEEEE?SS?SEEEE??SSS?B?S?EEES?EEEE?SS?SEEEESBB?TTTT??EEES?EEES?SS?SEEE??SEETTEE???BS?EEEEEEEES?SS?SEEE????????????TTS??TTTS?TT??????EEEEEEEE??SS?SEEEEEES?EEEEEEEES?SS?SEEEEEES?EEEEEEEES??TT??SS?SEEE?SS?EEEEEEE????????????EEEEEEEEEEEES???GGGEEEEEE??TT??S??????SSSEEEEEE??TTT?SSS??EEEEEEESSSTT???EEEEEEEEETTEEEEEEEEESGGG??SEE???BSS???GGG??STTEEEEEEEGGGTEEEEEEE?TTS?EEEEEEE 2VFN|A PF09252.5_Feld-I_B_seed 10 67 !Q:14,14|27,28|66,66 Q:0,13|15,26|29,65 SHHHHHHHHHHHHT?HHHHHHHHHHTT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSTT? 1PUO|A PF09253.5_Ole-e-6_seed 3 43 !Q:13,14|28,42 Q:0,12|15,27 HHHHHHHHHHTTT??HHHHHHHHHHHTS??????????????? 1SS3|A PF09254.6_Endonuc-FokI_C_seed 12 203 !Q:0,1|14,14|18,18|30,30|33,36|41,43|57,58|63,64|69,69|75,75|81,81|90,91|94,98|115,116|123,123|129,129|132,135|137,137|146,148|164,165|186,187|195,196|200,202 Q:2,13|15,17|19,29|31,32|37,40|44,56|59,62|65,68|70,74|76,80|82,89|92,93|99,114|117,122|124,128|130,131|136,136|138,145|149,163|166,185|188,194|197,199 ??HHHHHHHHHHHH?SSS?GGGGHHHHHTT?GG----GHHH---HHHHHHHHHHHTT??EEEE??SSSS?SEEEE?SSSTT?EEEEEEEE??TT?????HHHHHHHHHHHHHTTS??TTSSTT?GGGGS?TT?--?E-EEEEEEES???TTTTHHHHHHHHHHS??EEEEEHHHHHHHHHHHHHSS??SSTTTTT??SSB??? 1FOK|A PF09255.5_Antig_Caf1_seed 2 136 !Q:1,2|12,16|18,18|22,22|24,24|27,27|37,38|41,41|50,50|53,54|57,57|67,68|78,78|82,82|85,86|92,92|96,98|100,101|112,114|117,123|134,135 Q:0,0|3,11|17,17|19,21|23,23|25,26|28,36|39,40|42,49|51,52|55,56|58,66|69,77|79,81|83,84|87,91|93,95|99,99|102,111|115,116|124,133 E??EEEEEEEEE?????B?SSS?B?TT?EEEEEEEES??TT?BGGGEEEE?TT??TT?EEEEESSSS??EEEEEEEEE?TTS?EE??EETTB?SSS???B??SSEEEEEEEE???SS???????EEEEEEEEEE?? 3DOS|B PF09256.5_BaffR-Tall_bind_seed 2 31 !Q:0,4|19,19|22,30 Q:5,18|20,21 ?????TTEEEETTTTEEEE?EE????????? 1OQE|K PF09257.5_BCMA-Tall_bind_seed 2 39 !Q:0,1|7,7|11,11|24,26|38,38 Q:2,6|8,10|12,23|27,37 ??TTEEE?TTT?SEEETHHHHSSS???TTTHHHHTTTS? 2KN1|A PF09258.5_Glyco_transf_64_seed 25 329 !Q:7,11|14,14|26,27|41,42|45,47|52,61|66,68|71,71|77,94|97,98|105,106|109,110|118,118|121,121|125,125|138,139|149,149|155,155|158,160|169,169|173,175|181,182|187,187|198,198|204,206|208,208|210,210|222,223|239,239|241,241|246,247|249,254|259,286|289,290|292,292|309,310|312,316|318,318|322,323 Q:0,6|12,13|15,25|28,40|43,44|48,51|62,65|69,70|72,76|95,96|99,104|107,108|111,117|119,120|122,124|126,137|140,148|150,154|156,157|161,168|170,172|176,180|183,186|188,197|199,203|207,207|209,209|211,221|224,238|240,240|242,245|248,248|255,258|287,288|291,291|293,308|311,311|317,317|319,321|324,328 EEEEEEE-----SS?HHHHHHHHHHH--TTSTTEEEEEEEE??TT???THHH----------HHHT???SS?EEEEE-----------------?SS??GGGGGS??TT??SSEEEEE?TT-EEE?HHHHHHHHHHHT--TSTTSEEES?EEEEE-EE---ETTEEEEE?TTS???SSSSS??BSEE?TTEEEEETHH-HHHHH---T-S?HHHHHHHHHHT??HHHHHHHHHHHHHSS?S-EEEE??S------SEEE????????--------------??????TT--H-HHHHHHHHHHHHHHHT--S?????B?EEE--EETTB 1ON6|A PF09259.6_Fve_seed 2 111 !Q:0,0|13,13|19,21|26,26|40,42|45,46|61,64|66,66|70,70|82,83|89,89|96,96|102,103 Q:1,12|14,18|22,25|27,39|43,44|47,60|65,65|67,69|71,81|84,88|90,95|97,101|104,110 ?HHHHHHHHHHHH?EEEEE???EEEE?SSTTEEEEEEESB???SS??EEEEEETTEEEEEE????B?TTS?EEEEGGGTTTT??EETTS?EEEEEE?SSSTT??EEEEEEE 1OSY|A PF09260.6_DUF1966_seed 39 116 !Q:6,13|23,23|27,27|34,34|36,36|38,38|40,48|54,61|64,64|77,82|86,86|92,92|94,97|99,100|112,113 Q:0,5|14,22|24,26|28,33|35,35|37,37|39,39|49,53|62,63|65,76|83,85|87,91|93,93|98,98|101,111|114,115 EEEEET--------TEEEEEESS-TTS?EEEEEE?S?T-T------???EEEEE??--????TT?EEEETTTTEEEE?----?TTS?EEEEE?T----T??EEEEETGGGTT??TT 7TAA|A PF09261.6_Alpha-mann_mid_seed 126 121 !Q:0,0|2,3|12,16|29,29|40,52|56,56|58,61|70,91|106,106|108,108|114,114 Q:1,1|4,11|17,28|30,39|53,55|57,57|62,69|92,105|107,107|109,113|115,120 ?B??GGGTSSHH-----HHHHHHHHHHHH-HHHHHHHHTS???----------GGG?H----HHHHHHHH----------------------HHHHHHTBTTTTTS?S?HHHHH-HHHHHH 1HTY|A PF09262.6_PEX-1N_seed 32 112 !Q:0,0|20,20|26,26|32,33|36,36|38,50|52,52|59,60|64,64|76,77|79,97|101,102|105,105|110,111 Q:1,19|21,25|27,31|34,35|37,37|51,51|53,58|61,63|65,75|78,78|98,100|103,104|106,109 ?SEEEEEESSHHHHHHHHHS?SSHHH-HHHHH??EE?T-------------T?EEEEES--SSS?EEEEEEEEEES??S-------------------SEE??TT?EEEE?? 1WLF|A PF09263.5_PEX-2N_seed 2 87 !Q:0,0|9,10|14,14|18,18|27,28|31,32|40,42|46,46|50,50|53,59|73,74|77,77|84,84|86,86 Q:1,8|11,13|15,17|19,26|29,30|33,39|43,45|47,49|51,52|60,72|75,76|78,83|85,85 ?EEEEEEEE??SSS?EEE?HHHHHHTT??TT??EEEESSS?-?EEE?EEE?SS???????EEEEEHHHHHHTT??TT?EEEEEE?S? 1WLF|A PF09264.5_Sial-lect-inser_seed 2 198 !Q:1,1|7,9|25,28|32,32|46,46|65,65|69,69|77,78|80,80|85,85|93,93|120,121|124,126|134,135|139,139|160,160|168,168|170,170|173,175|181,181|189,189|195,195 Q:0,0|2,6|10,24|29,31|33,45|47,64|66,68|70,76|79,79|81,84|86,92|94,119|122,123|127,133|136,138|140,159|161,167|169,169|171,172|176,180|182,188|190,194|196,197 E?HHHHS???EEEEESSEEEEEEEE????TTS?EEEEEEEEEEEES?EEEEEEESSEEEEEEEEE?TTS?EEEEETT??S?EEEE?SHHHHTS?EEEEEEEETTTTEEEEEETTEEEEEE??EE???EEEEEEE??TTS?EEEEEEEEEEEETTEEEEEE?HHHHHTS?T-TS???GGGTT?EEEEEES?EEEES?SE 1W0P|A PF09265.5_Cytokin-bind_seed 18 335 !Q:0,0|12,12|27,35|37,37|39,39|61,73|76,76|92,92|104,122|135,136|138,138|141,141|168,168|172,175|197,197|202,204|206,206|218,218|223,227|229,231|241,253|270,275|277,278|282,284|289,293|299,300|302,302|307,307|322,322|325,326|328,328|332,332|334,334 Q:1,11|13,26|36,36|38,38|40,60|74,75|77,91|93,103|123,134|137,137|139,140|142,167|169,171|176,196|198,201|205,205|207,217|219,222|228,228|232,240|254,269|276,276|279,281|285,288|294,298|301,301|303,306|308,321|323,324|327,327|329,331|333,333 ?SEEEEEEEEES?HHHHHHHHHHHTSB????????-B?S?SEEEEEEEEGGGHHHHHHHTS-------------SS?HHHHHHHHHHHHHTT?SEEEEEEEEEE??--------??--?????HHHHHHHHHHTT??S?TT?EEEEEEEHHHHHTHHHHHHHHHHHTT?SSS????EEEEEEGGGHHHHHHHIIIII-TTTS???S?EEEEEEEGGGS?TTSS????-S---SSEEEEEEE????-----????HHHHHHHHHHHHHHHH------H--HHT???EESS???--SSHHH--H-HHHH?HHHHHHHHHHHHHH?TT??B?GGG?S? 3C0P|A PF09266.5_VirDNA-topo-I_N_seed 13 60 !Q:14,14|17,18|20,21|23,23|32,35|38,38|45,47 Q:0,13|15,16|19,19|22,22|24,31|36,37|39,44|48,59 EEEETTEEESSTTS?SB??T--T?THHHHHHH????TT?EEEEEE???HHHHTTSEEEEE 2H7G|X PF09267.5_Dict-STAT-coil_seed 3 114 !Q:32,32|35,35|72,74|111,113 Q:0,31|33,34|36,71|75,110 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS?SS?SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTS??? 1UUR|A PF09268.5_Clathrin-link_seed 17 24 !Q:12,13 Q:0,11|14,23 TTTHHHHHHTTS??HHHHHHHHHH 1C9L|A PF09269.6_DUF1967_seed 110 92 !Q:0,0|3,5|8,9|14,23|29,29|42,43|69,71|74,74|79,80|82,85|91,91 Q:1,2|6,7|10,13|24,28|30,41|44,68|72,73|75,78|81,81|86,90 ?EE---EE--EETT----------EEEEE?HHHHHHHTTEEE?-TGGGHHHHHHHHHHTTHHHHHHTTT??-TT?EEEE--T----TEEEE? 1UDX|A PF09270.5_BTD_seed 7 224 !Q:2,2|9,10|13,14|17,17|21,21|24,51|56,61|64,66|69,72|79,88|91,92|97,101|103,103|105,105|119,119|122,122|124,124|138,144|146,146|150,150|153,156|160,160|163,166|170,171|175,175|182,208|217,218|221,223 Q:0,1|3,8|11,12|15,16|18,20|22,23|52,55|62,63|67,68|73,78|89,90|93,96|102,102|104,104|106,118|120,121|123,123|125,137|145,145|147,149|151,152|157,159|161,162|167,169|172,174|176,181|209,216|219,220 SB?BTTSEE??EE??TT?TTT?EE?--------------------------?EETT------EE???SS????EEEEEE?---------SS??SSSS?????S-B?BTTSEEEEEESSS?EE?S?EEEEEEETTEEES??---??B?BSS?BE----EEE?SS----SSS??EEE?SSSEEE---------------------??????SSBTTEEE??SS??? 3BRG|C PF09271.6_LAG1-DNAbind_seed 12 211 !Q:11,11|13,13|16,20|23,24|34,39|43,46|59,75|80,84|86,86|93,93|95,95|99,105|108,110|113,125|132,134|137,139|142,142|144,147|159,169|173,176|180,185|199,210 Q:0,10|12,12|14,15|21,22|25,33|40,42|47,58|76,79|85,85|87,92|94,94|96,98|106,107|111,112|126,131|135,136|140,141|143,143|148,158|170,172|177,179|186,198 EEEEEEESEEE?B?TT?????SS??EEEEESSHH------HHH----HHHHHHHHGGGT??????????--?????STTT-----T?EEEEEE?S?SSS----???EE???TT?????????????EEEEEE?--TT???BT-T?-??SEEEEEEEEEE-----------TTT----EEE------EEEEEEEEEEESS???????????? 3BRG|C PF09272.5_Hepsin-SRCR_seed 2 110 !Q:2,2|7,7|11,11|28,29|45,45|47,47|60,61|64,65|71,71|78,78|80,80|89,90|93,93|101,103|105,109 Q:0,1|3,6|8,10|12,27|30,44|46,46|48,59|62,63|66,70|72,77|79,79|81,88|91,92|94,100|104,104 SS?SEEE?SSS?BEEEEETTTTEEEEEB??TTHHHHHHHHHHHTT?S?EEEEEEEEHHHH??TT??SEEEE?TTTGGG?S?STTSEEEE??SS?EEEEEEE???S????? 1O5E|L PF09273.6_Rubis-subs-bind_seed 43 190 !Q:0,1|10,13|23,24|27,28|39,47|49,49|61,62|73,73|77,77|81,87|91,91|95,95|97,97|101,112|131,131|134,134|138,138|142,143|147,150|154,154|157,174 Q:2,9|14,22|25,26|29,38|48,48|50,60|63,72|74,76|78,80|88,90|92,94|96,96|98,100|113,130|132,133|135,137|139,141|144,146|151,153|155,156|175,189 ??TTSTTHHH----HHHHHHHTT??SE--EEEEEESSSS--------?S?HHHHHHHHHHT??HHHHHHHHHT?SSS?TTT-------TTT?TTS?S?HHH------------HHHHHHHHHHHHHHHHHT?SS?HHH-HHH--HTT?---TTS?HH------------------HHHHHHHHHHHHHHH 3QXY|A PF09274.5_ParG_seed 3 76 !Q:0,0|11,11|21,21|26,27|32,32|36,37|57,58|74,75 Q:1,10|12,20|22,25|28,31|33,35|38,56|59,73 ?HHHHHTTTSS?TTSSTTTTT?GGGS??SSTT?EEE??EEEEHHHHHHHHHHHHHHT??HHHHHHHHHHHHHHH?? 1P94|A PF09275.5_Pertus-S4-tox_seed 2 110 !Q:0,1|4,4|38,39|46,46|58,58|60,61|75,76|102,103|108,109 Q:2,3|5,37|40,45|47,57|59,59|62,74|77,101|104,107 ??SS?EEEEEEEEEEEEEEEETTEEEEEEEEEEEEETT??SSSGGG?EEEEEEEETTS?S??HHHHHHHHHHHHT??EEEEEEEEEEEETTEEEEEEEEEEE??STTT?? 1BCP|D PF09276.5_Pertus-S5-tox_seed 2 97 !Q:0,3|29,29|33,34|41,42|44,44|47,47|65,65|70,74|80,80|83,85|89,90|94,97 Q:4,28|30,32|35,40|43,43|45,46|48,64|66,69|75,79|81,82|86,88|91,93 ????EEEEEEEEEEEEEETTEEEEEEEEE?TTS??EEEEEE??S?SS?THHHHHHHHHHHHHHTT?EEEE?????SSTTS?EE???EEE??TTS???- 1BCP|F PF09277.6_Erythro-docking_seed 2 58 !Q:1,2|4,4|26,27|47,47|49,50|52,57 Q:0,0|3,3|5,25|28,46|48,48|51,51 S??S?STTHHHHHHHHHHHHHHTTSS??HHHHHHHHHHHHHHHHHHH?S??S?????? 1PZQ|A PF09278.6_MerR-DNA-bind_seed 304 81 !Q:14,15|24,27|30,35|39,39|42,42|44,45|51,52|76,76 Q:0,13|16,23|28,29|36,38|40,41|43,43|46,50|53,75|77,80 HHHHHHHHHHHHTT??HHHHHHHH----HH------HHS-GG-G??HHHHH--HHHHHHHHHHHHHHHHHHHHHHH-HHHH 1Q07|A PF09279.6_EF-hand_like_seed 63 114 !Q:9,9|11,12|14,16|19,19|35,35|39,39|44,48|59,63|65,67|69,73|79,85|89,89|103,103|106,106|113,113 Q:0,8|10,10|13,13|17,18|20,34|36,38|40,43|49,58|64,64|68,68|74,78|86,88|90,102|104,105|107,112 HHHHHHHHT-T??S---TT?EEHHHHHHHHHHHSS?TTS?TTTS????-HHHHHHHHHH-----H???H-----HHHHT-------TEE?HHHHHHHHTSTTS?SS?HHHHSS? 1DJZ|A PF09280.6_XPC-binding_seed 36 64 !Q:2,2|7,7|20,20|35,35|42,44|59,60|62,63 Q:0,1|3,6|8,19|21,34|36,41|45,58|61,61 TG-GGTT?TTTTTHHHHHTT?GGGHHHHHHHHHTT?HHHHHH---HHTTHHHHHHHHHS-?S?? 1PVE|A PF09281.5_Taq-exonuc_seed 4 143 !Q:0,1|4,4|7,7|10,11|14,14|24,24|26,29|32,33|48,48|51,55|63,66|86,89|91,93|102,102|105,107|116,116|118,121|123,123 Q:2,3|5,6|8,9|12,13|15,23|25,25|30,31|34,47|49,50|56,62|67,85|90,90|94,101|103,104|108,115|117,117|122,122|124,142 ??SS?EE?SS??TT?EEEEEESSS?T----TT??EEEEEEEBTTBEEB?SS-----HHHHTTT?---SSBBSTTHHHHHHHHHHTT????B???HHHHHHHH?TT???HHHHHHHH-S????S?HHHHHHHHHHHHHHHHHHH 3RRH|A PF09282.5_Mago-bind_seed 11 27 !Q:5,6|9,9|13,13|16,17|20,21|24,26 Q:0,4|7,8|10,12|14,15|18,19|22,23 TEEEE??EE?TTS?EE??EE??TT??? 1RK8|C PF09284.5_RhgB_N_seed 6 276 !Q:0,0|5,5|13,15|18,18|28,29|40,40|42,43|47,47|53,54|57,57|67,70|78,78|82,83|93,94|105,106|110,110|118,118|122,123|125,126|135,136|139,139|142,142|152,152|163,164|169,169|173,178|182,182|185,187|193,198|201,201|204,204|207,207|209,211|215,215|218,218|227,227|231,232|234,237|251,254|256,264|269,269|273,273 Q:1,4|6,12|16,17|19,27|30,39|41,41|44,46|48,52|55,56|58,66|71,77|79,81|84,92|95,104|107,109|111,117|119,121|124,124|127,134|137,138|140,141|143,151|153,162|165,168|170,172|179,181|183,184|188,192|199,200|202,203|205,206|208,208|212,214|216,217|219,226|228,230|233,233|238,250|255,255|265,268|270,272|274,275 ?EEEE?SSEEEEE???TT?EEEEEETTT??EEEEEETTEE?B-?SSS?BEETT??SS?EEEEEEETT----EEEEEEE?SSE--EEEEEEETT??EEEEEEEESS??TTS?EEEEEEE?TTT??E--EETTGGGG??TT?EE-EETTTEEEE-TTEEEEGGGG??BGGG?SEE------EEE?SS--?EEEEE??--??TT?SS?TT?B???EEE?SS?EEEEEEEE?STT??S????EEEEEEEEEEESS????S?-----???GGGG-GTT?TT 3NJV|A PF09285.6_Elong-fact-P_C_seed 108 61 !Q:5,22|29,29|32,33|38,38|41,42|45,45|54,54 Q:0,4|23,28|30,31|34,37|39,40|43,44|46,53|55,60 EEEEB???????????-?????-EEEEBT-TS-?EEEE?SS??TT?EEEEETTT-TEEEEE 3OYY|A PF09286.6_Pro-kuma_activ_seed 124 289 !Q:2,2|8,9|12,12|14,16|18,18|20,21|27,29|31,33|35,36|47,48|50,50|57,78|80,85|94,96|112,113|118,136|138,138|142,142|155,169|175,179|184,187|189,201|204,214|219,221|224,226|228,228|233,268|275,278|281,284|287,288 Q:0,1|3,7|10,11|13,13|17,17|19,19|22,26|30,30|34,34|37,46|49,49|51,56|79,79|86,93|97,111|114,117|137,137|139,141|143,154|170,174|180,183|188,188|202,203|215,218|222,223|227,227|229,232|269,274|279,280|285,286 TT?EEEEE??TT?E---E-E--EEEEE-??S?--H--HHHHHHHHHH--H?TTSTTT----------------------T??--??HHHHHHHH???HHHHHHHHHHHHHHT-?EEEE-------------------E?TTS?EEEEEEEHHHHH---------------HHSTT?--??EEEE---?S-------------SS??---------EEEE--?SS???B?GGGT------------------------------------TTEEEE----ET----SS?? 3EE6|A PF09287.5_CEP1-DNA_bind_seed 2 198 !Q:0,1|8,8|15,15|23,23|26,27|33,33|36,37|46,47|53,55|65,65|69,69|76,76|79,79|81,84|91,92|98,98|105,105|111,112|115,115|125,126|129,130|141,141|146,146|162,162|166,166|179,179|181,181|196,197 Q:2,7|9,14|16,22|24,25|28,32|34,35|38,45|48,52|56,64|66,68|70,75|77,78|80,80|85,90|93,97|99,104|106,110|113,114|116,124|127,128|131,140|142,145|147,161|163,165|167,178|180,180|182,195 ??EEEEEE?HHHHTT?SSEEEEE?TT??EEEEE?TT??EEEEEEEE??TTTTT???EEEEEEEEE?SSS?HHHHTT?TT?B????HHHHHT??SSSTT?SEEEES?SSEEE--EE?TTSSEEEEE??TT??EEEEEEEESS?GGGS?HHHHTSEEEEEEEEE?TTS?EEEEEEEEEEEE?S?HHHHHHHHHHHHHH?? 1T4W|A PF09288.5_UBA_3_seed 6 55 !Q:1,1|4,7|20,21|33,34|37,38|41,42|54,54 Q:0,0|2,3|8,19|22,32|35,36|39,40|43,53 S?SS????SHHHHHHHHHHT??HHHHHHHHHHS??SS??SS??HHHHHHHHHHT? 1TTE|A PF09289.5_FOLN_seed 14 22 !Q:0,0|3,6|14,14|18,18 Q:1,2|7,13|15,17|19,21 ?TT????TTEEEEE?TTS?EEE 1LR9|A PF09290.6_AcetDehyd-dimer_seed 62 165 !Q:17,18|34,34|40,40|57,58|69,70|73,75|86,87|89,93|112,112|120,121|127,127|131,131|135,137|144,144|153,154|157,160|164,164 Q:0,16|19,33|35,39|41,56|59,68|71,72|76,85|88,88|94,111|113,119|122,126|128,130|132,134|138,143|145,152|155,156|161,163 HHHHHHHHHHHHHHTTS-?EEEEEEEEEEEGGGS?HHHHT?HHHHHHHHHHHHHHTT??SSEEEEEEEE??SS???EEEEEEEEES--S??---HHHHHHHHHHHHHHHHTT?TTEEESS??EEEEE?TTS?EEE---TTTEEE?EEEEEEEE--EE????SSS? 4JN6|B PF09291.5_DUF1968_seed 4 91 !Q:0,0|7,7|12,13|21,22|24,24|26,35|39,39|42,44|49,49|54,54|59,59|65,65|68,69|75,75|77,77|79,90 Q:1,6|8,11|14,20|23,23|25,25|36,38|40,41|45,48|50,53|55,58|60,64|66,67|70,74|76,76|78,78 ?EEEEEB?SSSS??EEEEEES??T-T?????---??STT?EE???EEEE?SSSS?EEEE?EEEES?TT??HHHHS?S?S????????--?? 4EI5|C PF09292.5_Neil1-DNA_bind_seed 6 39 !Q:8,8|13,13|16,16|21,21|25,25|32,34|37,38 Q:0,7|9,12|14,15|17,20|22,24|26,31|35,36 HHHHHHHH?SSTT?TT?EEEE?TTS?EEEESS???TT?? 1TDH|A PF09293.5_RNaseH_C_seed 8 127 !Q:1,1|13,13|20,21|25,25|32,33|36,42|51,53|55,55|64,64|69,69|80,80|85,85|99,103|116,116|122,122|126,126 Q:0,0|2,12|14,19|22,24|26,31|34,35|43,50|54,54|56,63|65,68|70,79|81,84|86,98|104,115|117,121|123,125 S?HHHHHHHHHHH?BGGGTB??TTS?TTHHHH??TT???????HHHHHHHH---H?GGGHHHHS?HHHH-HHHHHHHHHH?GGGS?HHHHHHHHHHHHT?????THHHHHHHHHTT?TTTTT?GGG? 3H8J|A PF09294.5_Interfer-bind_seed 96 121 !Q:2,5|7,7|11,13|26,27|31,34|37,37|45,45|47,47|49,49|60,69|73,74|82,82|84,85|88,88|97,100|109,114|119,120 Q:0,1|6,6|8,10|14,25|28,30|35,36|38,44|46,46|48,48|50,59|70,72|75,81|83,83|86,87|89,96|101,108|115,118 SB????E-EEE---EEETTEEEEEEE??EEE?---SS?EEEHHHH?T-T?EEEEEEEETT--??----??EEE??SSSEEEE?S??TT?EEEEEEEE----EETTTTEE??????EEEE?? 2KZ1|B PF09295.5_ChAPs_seed 14 480 !Q:0,8|11,14|16,16|31,50|67,73|79,79|82,83|85,109|133,154|161,164|167,167|170,171|175,176|180,180|182,185|204,206|209,209|212,215|234,234|249,250|266,266|280,280|287,287|290,291|315,326|341,341|344,344|360,360|371,376|379,386|389,398|400,421|424,430|436,436|441,442|460,460|472,479 Q:9,10|15,15|17,30|51,66|74,78|80,81|84,84|110,132|155,160|165,166|168,169|172,174|177,179|181,181|186,203|207,208|210,211|216,233|235,248|251,265|267,279|281,286|288,289|292,314|327,340|342,343|345,359|361,370|377,378|387,388|399,399|422,423|431,435|437,440|443,459|461,471 ?????????EE????S?HHHHHHHHHHHHHH????????????????????EEEEEETTTTEEEEEE???????EEEEE?SS??B------???????????-???????TTHHHHHHHHHHHHHHHHHTTTT----------------------TGGGTS????SS?EE??GGG??SSS?H----HHHHHHTHHHHTTSGGGG???TT?SS--??SSSSHHHHHHHHHHHHHT?HHHHHHHHHHHHHH?-GGGHHHHHHHHHHTT?HHHHHHHHHHHHH?TTSTTS?SS??HHHHHHHHHHHHHHHHHHHHHTT??----------HHHHHHHHHHHHHH?TT?HHHHHHHHHHHHHHT?HHHHHHHHHT????--SS????????SS???????---B????????????????????--SS???????HHHHT?TTTT??HHHHHHHHHHHHHHHHH?HHHHHHHHHHH???????? 4GNS|B PF09296.6_NUDIX-like_seed 75 212 !Q:13,13|16,55|58,59|67,93|95,95|105,107|112,135|143,145|148,176|179,179|185,191|194,195 Q:0,12|14,15|56,57|60,66|94,94|96,104|108,111|136,142|146,147|177,178|180,184|192,193|196,211 EEEEEEEETTEEE?GG----------------------------------------GS??EEETTTT---------------------------T?TTSEEEEEE---EETT------------------------EEEEEEE???SS?----------------------------EE?GGGGT-------TS?-HHHHHHHHHHHHHHHH 2GB5|A PF09297.6_zf-NADH-PPase_seed 63 35 !Q:5,5|9,10|15,15|18,18|21,21|25,26|31,31|34,34 Q:0,4|6,8|11,14|16,17|19,20|22,24|27,30|32,33 HHTSB?TTT??BEEE?SS-BS?EEE--SSSS?EE? 2GB5|A PF09298.6_FAA_hydrolase_N_seed 94 146 !Q:2,3|9,9|12,14|16,19|36,38|40,57|59,59|61,63|70,71|87,87|105,117|119,120|125,125|139,140|144,144|146,146 Q:0,1|4,8|10,11|15,15|20,35|39,39|58,58|60,60|64,69|72,86|88,104|118,118|121,124|126,138|141,143|145,145 TT??EEEEE?SS?-?S---?EEEEEETTEEEETTTS---G------------------G-G??-STTTTT?-GGGGGSSSSHHHHHT?HHHHHHHHHHHHHHHBT-------------T??HHHH?HHHHHHHEEEGGG-?EEE?S- 1QCO|A PF09299.6_Mu-transpos_C_seed 36 93 !Q:6,9|12,13|16,17|27,27|31,32|34,36|42,42|45,45|50,51|53,53|56,58|64,64|76,76|78,79|82,87 Q:0,5|10,11|14,15|18,26|28,30|33,33|37,41|43,44|46,49|52,52|54,55|59,63|65,75|77,77|80,81|88,92 HHHTSE----EB??EE??TTSEEEEEE?TTS??E---EEEEE?GG-GTSS--S?SE---EEEEE?GGGTTTEEEEE?T--TS-----?EEEEE 4FCY|A PF09300.5_Tecti-min-caps_seed 3 84 !Q:0,4|8,10|13,14|17,33|35,40|42,45|47,48|50,53|56,83 Q:5,7|11,12|15,16|34,34|41,41|46,46|49,49|54,55 -????SSS???SS??TT?????????????????B??????S????S??S????SS???????????????????????????? 1W8X|M PF09301.5_DUF1970_seed 3 117 !Q:0,3|27,27|29,29|32,32|35,38|41,41|44,46|48,48|50,52|54,95|115,116 Q:4,26|28,28|30,31|33,34|39,40|42,43|47,47|49,49|53,53|96,114 ????SSHHHHHHHHHHHHHHHHHHHTT?S?SS?TT????TT?SS???S?S???S??????????????????????????????????????????TTTTHHHHHHHHHHHHHHT?? 1W8X|P PF09302.6_XLF_seed 30 273 !Q:1,2|5,6|10,10|12,22|30,31|37,40|45,53|56,58|80,86|103,117|124,128|144,145|156,157|160,163|185,214|227,261|271,272 Q:0,0|3,4|7,9|11,11|23,29|32,36|41,44|54,55|59,79|87,102|118,123|129,143|146,155|158,159|164,184|215,226|262,270 S??EE??BTT-B?---------?EEEEEEE--TTEEE----EEEE?--------SS?--EEEEEEEHHHHHHHHTTSSTT???---?HHHHHHHHHHHHHHHH?-----?????????EEEEEE-----TTEEEEEEEEESSSS--EEEEEEEEEE??HH----HHHHTTHHHHHHHHHHHHHHH------------------------------HHHHHHHHHHHH-----------------------------------HHHHHTTTS?? 3SR2|C PF09303.5_KcnmB2_inactiv_seed 7 32 !Q:0,2|5,10|15,15 Q:3,4|11,14|16,31 ???SS??????SSSS?STTSSHHHHHHHHTTT 1JO6|A PF09304.5_Cortex-I_coil_seed 4 114 !Q:0,12|35,38|45,47 Q:13,34|39,44|48,113 ------------?HHHHHHHHHHHHHHHHHHHHHH----HHHHHH---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 1D7M|A PF09305.5_TACI-CRD2_seed 2 41 !Q:0,3|27,28|36,40 Q:4,26|29,35 ????GGGTEEEETTTTEEEEGGGGTTS??GGGHHHH????? 1XU1|R PF09308.5_LuxQ-periplasm_seed 6 241 !Q:0,10|40,40|50,52|71,72|79,79|87,87|89,89|95,96|107,108|113,113|136,136|140,140|152,152|155,155|168,168|183,185|187,188|191,193|198,212|232,240 Q:11,39|41,49|53,70|73,78|80,86|88,88|90,94|97,106|109,112|114,135|137,139|141,151|153,154|156,167|169,182|186,186|189,190|194,197|213,231 ???????????THHHHHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHH??-HHHHHHHHHHHHHHSGGG??SEEEEE?SSSEEEE?S?TGGGT??HHHHHHHHHH??SSSS?EEEEEEETTEEEEEEEEEEEEE?TTT?BEEEEEEEEEE?TT?HHHHHHHHHHHT?SEEEEEETTEEEEE???S?-SS?-?HHHH???????????????EEEEEEETTEEEEEEEEEE????????? 3C30|A PF09309.5_FCP1_C_seed 4 295 !Q:0,276|294,295 Q:277,293 ------------------------------------------------------------------------------?----------------------------------------------------------------------------------------------------???????????---???????-----------------????????????????????????????---------?????----??????????-???SHHHHHHHHHHHHHHHH?- 1ONV|B PF09312.6_SurA_N_seed 19 118 !Q:0,2|33,37|64,67|84,85|98,99 Q:3,32|38,63|68,83|86,97|100,117 ???EEEEESSSEEEHHHHHHHHHHHHHHHHTTT?????HHHHHHHHHHHHHHHHHHHHHHHHTT????HHHHHHHHHHHHHHTT??HHHHHHHHHHHT??HHHHHHHHHHHHHHHHHH 1M5Y|A PF09313.6_DUF1971_seed 44 86 !Q:2,4|11,11|19,24|27,27|37,37|44,44|47,49|57,57|60,64|66,66|69,70|80,80 Q:0,1|5,10|12,18|25,26|28,36|38,43|45,46|50,56|58,59|65,65|67,68|71,79|81,85 EE???EETTTS?GGGGSSB---???TT?EEEEEEEES?EEEEEE?TT??-EEEEEEE?TT?????B?TT??EEEEESSTT?EEEEE 3M70|A PF09325.5_Vps5_seed 22 253 !Q:0,34|86,87|89,90|171,172|174,176|214,214|223,223|248,252 Q:35,85|88,88|91,170|173,173|177,213|215,222|224,247 ----------------------???????-----?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT??S--HHHHHHHHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--S?--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHTTTT?HHHHHHHHHHHHHHHHHHHHHHHT????? 4FZS|A PF09329.6_zf-primase_seed 37 57 !Q:8,9|12,13|19,21|26,30|33,33|36,36|39,56 Q:0,7|10,11|14,18|22,25|31,32|34,35|37,38 EEETTEEE??SB?-TTSSB???EEET-----TT?SS?TT?????----????-???? 3H15|A PF09330.6_Lact-deh-memb_seed 19 292 !Q:7,7|22,22|25,26|41,100|110,110|119,119|139,141|146,147|186,187|190,190|192,193|195,198|229,230|247,247|250,250|254,255|260,262|273,273|276,277|285,287|290,291 Q:0,6|8,21|23,24|27,40|101,109|111,118|120,138|142,145|148,185|188,189|191,191|194,194|199,228|231,246|248,249|251,253|256,259|263,272|274,275|278,284|288,289 EEEEEES?HHHHHHHHHHHHHH?SS??SEEEEEEHHHHHHH????????????????????????????????????????????????????????????HHHHHHHHH?SEEEEEEE?TTHHHHHHHHHHHHHHHSS--?EEEE??HHHHHHHHHHHTTHHHHHHHHHHHTTTTEEEEEEEEEE??TT?S??S????HHHHTTEEEEEEEEETTTTEEEEEEEEETT??HHHHHHHHHHHHHHTT?BS?SSS??TTTS???HHHHHHHHHH?TT??BSTTTTT???SS?? 1F0X|A PF09332.6_Mcm10_seed 9 383 !Q:0,278|280,280|282,283|285,285|295,296|301,302|310,311|319,319|324,324|326,326|329,329|338,339|341,342|346,346|348,350|354,356|360,361|363,382 Q:279,279|281,281|284,284|286,294|297,300|303,309|312,318|320,323|325,325|327,328|330,337|340,340|343,345|347,347|351,353|357,359|362,362 ----------------------------------------------------------------------------------------------------?-----------?----------------?---------------------------------------------------------------------------------------------------------------------------------------------------??S?S??E-EEEEEETTT??EESS??HHHHHTT??EEEEEEE?EEEE?T-TS?EEEESSSS??S??TTT?S???EEE???SSS??S????---------------- 2KWQ|A PF09334.6_tRNA-synt_1g_seed 39 502 !Q:5,7|12,13|36,36|38,38|40,40|49,50|63,64|72,72|84,84|87,89|116,116|133,137|141,156|159,159|162,163|165,166|168,170|174,175|179,183|190,190|192,192|196,197|199,200|211,211|219,238|247,254|266,267|270,273|276,276|278,280|282,283|286,286|288,288|290,295|297,300|306,306|309,309|327,327|331,340|342,345|348,348|351,354|359,361|363,363|366,368|395,396|398,398|402,403|405,405|407,416|419,420|423,424|431,431|433,433|441,441|444,444|451,451|453,455|466,466|468,469|473,473|477,477 Q:0,4|8,11|14,35|37,37|39,39|41,48|51,62|65,71|73,83|85,86|90,115|117,132|138,140|157,158|160,161|164,164|167,167|171,173|176,178|184,189|191,191|193,195|198,198|201,210|212,218|239,246|255,265|268,269|274,275|277,277|281,281|284,285|287,287|289,289|296,296|301,305|307,308|310,326|328,330|341,341|346,347|349,350|355,358|362,362|364,365|369,394|397,397|399,401|404,404|406,406|417,418|421,422|425,430|432,432|434,440|442,443|445,450|452,452|456,465|467,467|470,472|474,476|478,501 EEEEE???BTTS??BHHHHHHHTHHHHHHHHHHHHT-T?E-EEEEEEEB??SHHHHHHHHHHT??HHHHHHH-HHHHHHHHHHH-HT???SEEEETTSHHHHHHHHHHHHHHHHTT?EEEEEEEEEEBTTTTB--???GGG--------------??SB?SS--S??S???TTT?-SSS?????TTSSBS?B?TTT??B?-EEEEEEEEEE?GGGTHHH--------------------HHHHHHSS?-----??HHHHHHHHHHH--TT????EE?E---E??SS-S?B?-----S??-?SSSTT?EE?HHHHGGGHHHHHHHHHH-HHT----------T?---TT-TT----HHHH---B?SS??-EEEEEEEEGGGHHHHHTHHHHHHHTT??B?SSS??B?B?-------??SB??EE??EEETTE-E?BTTTTBS?BH-HHHTTT-S?--HHHHHHHHHH-T??SSS?EEE?HHHHHHHHHHTTTTTHHHHHHHHH 3U20|A PF09336.5_Vps4_C_seed 26 69 !Q:0,1|5,5|11,13|16,17|22,26|30,37|48,53|68,68 Q:2,4|6,10|14,15|18,21|27,29|38,47|54,67 ??EEE?SSSTT-?-EE??TTTS?----SSS????-???HHHHHHHHHT??????HHHHHHHHHHHHHH? 2RKO|A PF09339.5_HTH_IclR_seed 93 62 !Q:11,12|15,15|18,25|27,28|39,40 Q:0,10|13,14|16,17|26,26|29,38|41,61 HHHHHHHHHHT??SS?SS--------E--EHHHHHHHHT??HHHHHHHHHHHHHHTSEEESS 1MKM|A PF09341.5_Pcc1_seed 57 103 !Q:8,8|10,10|25,25|29,30|32,32|37,38|43,43|45,58|62,63|69,76|99,102 Q:0,7|9,9|11,24|26,28|31,31|33,36|39,42|44,44|59,61|64,68|77,98 EEEEEEEE?S?HHHHHHHHHHHTHH-HHT??S?SSEE??EESS-S--------------EEE--EEEEE--------SSHHHHHHHHHHHHHHHHHHHT???? 3ENC|A PF09346.5_SMI1_KNR4_seed 178 354 !Q:0,2|8,10|12,12|17,18|22,25|28,28|35,80|83,83|93,96|98,99|102,102|116,247|256,260|272,272|276,288|290,291|299,306|310,312|317,334|337,338|344,350 Q:3,7|11,11|13,16|19,21|26,27|29,34|81,82|84,92|97,97|100,101|103,115|248,255|261,271|273,275|289,289|292,298|307,309|313,316|335,336|339,343|351,353 ???HHHHH---H-HHHH--HTS-???HH-HHHHHH----------------------------------------------HH?SEEETTEEE????S--SS?HHHHHHHHHHHHS---------------------------------------------------------------------------------------------------------------------------------???TTEEEEEE----?SSEEEEEETTS?BTT-------------B??EEEEETT--------TEE---EEEE------------------ES--SHHHH-------HHH 2PRV|A PF09347.5_DUF1989_seed 144 220 !Q:4,4|7,7|14,14|17,17|24,24|27,29|40,40|43,47|51,51|59,62|64,64|67,69|72,74|79,79|83,84|91,91|98,101|105,105|112,116|124,124|126,126|128,131|133,141|153,153|157,159|162,164|167,173|177,180|190,190|194,196|201,205|208,208|217,217 Q:0,3|5,6|8,13|15,16|18,23|25,26|30,39|41,42|48,50|52,58|63,63|65,66|70,71|75,78|80,82|85,90|92,97|102,104|106,111|117,123|125,125|127,127|132,132|142,152|154,156|160,161|165,166|174,176|181,189|191,193|197,200|206,207|209,216|218,219 EEEE?BT?EEEEEE?TT?EEEEEE?SS???EEEEEEETTE-EE-----EEB?HHHHHHH----H?SB-??TT--?EEEB?TTT??EEEEEE-EETTTT????TTS?EEEESS?????HHHHHHH-H?S--??S--------?SHHHHHHHHHH-HHH???HH---HH-------HTT????EEEEEEEEE?TTT??-EEEE?????TT?EEEEEESS?EE 3SIY|A PF09349.5_OHCU_decarbox_seed 139 268 !Q:0,7|12,12|23,27|38,41|46,50|52,52|56,56|71,91|103,104|111,118|124,135|139,156|163,163|176,176|179,184|186,190|192,194|196,196|199,202|209,236|240,240|243,243|245,246 Q:8,11|13,22|28,37|42,45|51,51|53,55|57,70|92,102|105,110|119,123|136,138|157,162|164,175|177,178|185,185|191,191|195,195|197,198|203,208|237,239|241,242|244,244|247,267 ??------HHHH-HHHHTTSSTT?----HHHHHHHHHT----TGGG-----S?SSH-HHHHHHHHHHHHHS?--------------------HHHHHHHHHHS??HHHHHH--------HHHTT????????????TTS?----------------?HHHHHH-HHHHHHHHHHHH-SS??????T-----T-??H-HH----HHHHHH----------------------------HHH-TS?H--HHHHHHHHHHHHHHHHHHHHH 2O8I|A PF09351.5_DUF1993_seed 60 200 !Q:8,8|12,16|37,38|42,42|46,47|53,54|75,78|80,80|82,84|88,107|109,109|127,128|133,134|140,140|143,147|149,151|156,156|161,161|163,163|190,193|199,199 Q:0,7|9,11|17,36|39,41|43,45|48,52|55,74|79,79|81,81|85,87|108,108|110,126|129,132|135,139|141,142|148,148|152,155|157,160|162,162|164,189|194,198 HHHHTHHH-HHH-----HHHHHHHHHHHHHHHHHHHT??HHH-HHT??SSTTS??HHHHHHHHHHHHHHHHHHHT----T?G---GGS?-----------???-????S-HHHHHHHHHHHHHHHHT??GGGG--TTTTT?EE??---T---TSTT?BEEH-H-HHHHHTHHHHHHHHHHHHHHHHHHHT????HHHHH? 3QTH|A PF09358.5_UBA_e1_C_seed 57 178 !Q:0,1|16,18|20,21|26,30|36,49|54,54|61,76|90,92|102,102|107,108|112,117|140,147|150,151|161,163|167,167|170,173|175,176 Q:2,15|19,19|22,25|31,35|50,53|55,60|77,89|93,101|103,106|109,111|118,139|148,149|152,160|164,166|168,169|174,174|177,177 ??EEEEETTTTEEEEE???B??EEEE-----TTEEE--------------ETTT?EEEEES------?--------?BHHHHHHHHHHTT-??EEEEEEETT-EEEE--ETT----??HHHHHHHTTSBHHHHHHHHSSS-----???SS??EEEEEEEEE-?-TTS?EE-???E--E 4II2|A PF09359.5_VTC_seed 44 566 !Q:0,1|9,9|25,25|27,91|99,99|102,103|113,113|116,117|125,125|127,127|131,141|150,163|165,165|173,173|184,186|201,202|204,204|206,308|323,325|331,331|333,333|347,348|351,353|368,372|377,377|380,380|384,471|474,474|479,479|484,484|487,487|490,491|498,501|510,535|543,543|548,548|551,551|554,555 Q:2,8|10,24|26,26|92,98|100,101|104,112|114,115|118,124|126,126|128,130|142,149|164,164|166,172|174,183|187,200|203,203|205,205|309,322|326,330|332,332|334,346|349,350|354,367|373,376|378,379|381,383|472,473|475,478|480,483|485,486|488,489|492,497|502,509|536,542|544,547|549,550|552,553|556,565 ??EEEEEEE?HHHHHHHHHHHHTTS?B???????????????????-----------???????-???????----????????????????EEEEEEE?TT-?HHHHHHHHT?TT??EEEEEEE-S?GGG?--------??EEEEEEEE----??????????E-EEEEEEE?GGGHHHHHHS???HHHHHHHHHHHHHT??H-H-------------------------------------------------------------------------------------------------------HHHHHHHHHHHHHH---HHHHT-T?EEEEEEEEEEEEE??TT-??SEEEEEEEEEEEEE?-???SSSS?SS?TTS----------------------------------------------------------------------------------------SS?SSTT-SSSS?TT-TT??GGGEEE??--SEEEEEEE????????????--????????????HHHHHHH-TSTT?EE?TT??HHHHHHHHHH 3G3T|A PF09360.5_zf-CDGSH_seed 158 67 !Q:0,0|4,4|11,11|15,28|32,33|36,37|40,42|48,49|52,53|55,55|60,61|63,63 Q:1,3|5,10|12,14|29,31|34,35|38,39|43,47|50,51|54,54|56,59|62,62|64,66 ?TTS?EEEESS?EEE--------------ESS??EE??BT---TEEEE??SS??S-STTB??S-HHH 4F1E|A PF09363.5_XFP_C_seed 93 227 !Q:0,0|6,6|8,8|23,23|27,33|39,42|68,69|71,72|79,79|86,86|88,89|91,92|94,94|98,99|104,110|115,116|120,120|128,128|149,151|153,155|157,158|168,168|184,189|216,217|223,225 Q:1,5|7,7|9,22|24,26|34,38|43,67|70,70|73,78|80,85|87,87|90,90|93,93|95,97|100,103|111,114|117,119|121,127|129,148|152,152|156,156|159,167|169,183|190,215|218,222|226,226 ?SEEEE?S?HHHHHHHHHHSEEE?TTT?-??---SSTTT---?SEEEEEESHHHHHHHHHHHHHHHHT--T??EEEEEE?BGGGGS?T--T--T?TTS??HHHH-------HHHH-?SSS?EEEEESS?HHHHHHHTTTSTTGGGEEEE???S???S??HHHHHHHTT?SHHHHHHHHHHHHHH------HHHHHHHHHHHHHHHHHHHHHHHHSS??HHHHT???T 3AHD|A PF09364.5_XFP_N_seed 6 398 !Q:0,2|29,29|32,36|39,40|45,45|48,52|75,75|77,78|103,103|107,107|122,122|127,127|130,131|137,137|139,141|146,146|158,158|161,161|187,188|193,193|202,202|210,210|216,216|236,236|241,242|270,272|274,275|278,281|289,290|296,296|299,305|309,310|313,313|322,322|324,324|330,330|345,345|351,351|355,355|357,357|365,366|374,374|383,390|395,396 Q:3,28|30,31|37,38|41,44|46,47|53,74|76,76|79,102|104,106|108,121|123,126|128,129|132,136|138,138|142,145|147,157|159,160|162,186|189,192|194,201|203,209|211,215|217,235|237,240|243,269|273,273|276,277|282,288|291,295|297,298|306,308|311,312|314,321|323,323|325,329|331,344|346,350|352,354|356,356|358,364|367,373|375,382|391,394|397,397 ???HHHHHHHHHHHHHHHHHHHHHHHBSS?TT?---?SS??GGGB?SS?????TTHHHHHHHHHHHHHHHHHHTB?B??EESSGGGHHHHHHHHHHHTHHHHH?TTS?SSHHHHHHHHHHBT?TTSB?SS??TTSTT?S???SSTT?HHHHHHHHHTT?TT?EEEEEEETTGGGSHHHHHHGGGGGS??TTTS?EEEEEEEE?SBSSSSB?HHHHS?HHHHHHHHHHTTEEEEEEE?SSSS??HHHHHHHHHHHHHHHHHHHHHHHHHHT---T??SS-???EEEEEEE??TTTTS?SE-------ETT--EE?TTSGGGSS?S?TTTTT?HHHHHHHHHHHHHT?GGGTB?TTS?B?HHHHTTS??GGGSTTT?GGGSGGGT????????GGGG??T 3AHD|A PF09367.5_CpeS_seed 66 199 !Q:0,0|9,9|22,24|27,28|32,33|44,44|47,47|58,60|65,66|69,69|72,73|81,93|104,104|107,107|109,109|117,131|136,136|140,141|148,148|151,152|167,167|181,187|191,191|198,198 Q:1,8|10,21|25,26|29,31|34,43|45,46|48,57|61,64|67,68|70,71|74,80|94,103|105,106|108,108|110,116|132,135|137,139|142,147|149,150|153,166|168,180|188,190|192,197 ?HHHHHHHH?EEEEEEEEEEET---TT--TEE--EEEEEEEEEE-EE?TTSHHHHHHH---HHTT??TT-TB??EEEEEEE???????---???EEEEEEEEEE?TT?S-SEEEEEE??????????---??EEEE?TTS-?EEEEEE?SS?-EEEEEEEEEETTEE-EEEEEEEETTEEE-------EEE-EEEEEE? 3BDR|A PF09370.5_TIM-br_sig_trns_seed 20 293 !Q:4,4|15,17|21,32|49,49|55,55|65,66|86,86|93,93|96,96|98,98|104,104|107,107|110,111|124,125|130,131|133,133|137,140|152,153|169,169|172,173|176,176|186,186|190,190|197,197|199,216|235,235|237,238|247,248|260,260|263,265|292,292 Q:0,3|5,14|18,20|33,48|50,54|56,64|67,85|87,92|94,95|97,97|99,103|105,106|108,109|112,123|126,129|132,132|134,136|141,151|154,168|170,171|174,175|177,185|187,189|191,196|198,198|217,234|236,236|239,246|249,259|261,262|266,291 HHHH-HHHHHHHHTT-??EEE------------EEESSHHHHHHHHHTT?SEEEE?HHHHHHHTT??GGGGGBTEEEHHHHHHHHH-HHHGGG?SS-S?EEEEE?TT?TT??HHHHHHHHHHHT??EEEE?-S?GGG?--?HHHHHHHHHTT??HHHHHHHHHHHHHTT?EE??EE?SHHHHHHHH-HHT?SEEEEE?S????????----??????HHHHHHHHHHHHHHHHHH?S??EEEEESTT??SHHHHHHHHHH?TT-??EEEESHHHHHHHHHHHHHHHHHHHHT? 2P10|A PF09371.5_Tex_N_seed 145 229 !Q:7,8|23,24|32,32|39,40|73,75|78,80|88,89|103,108|128,128|132,137|140,140|147,152|156,162|165,168|170,170|181,183|193,193|202,203|210,210|212,212|216,216|219,221 Q:0,6|9,22|25,31|33,38|41,72|76,77|81,87|90,102|109,127|129,131|138,139|141,146|153,155|163,164|169,169|171,180|184,192|194,201|204,209|211,211|213,215|217,218|222,228 HHHHHTT??HHHHHHHHHHHTTT??HHHHHHH?HHHHTS??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT???HH---HHHHHHH??SHHHHHHHHTTTS?-????HHHHHHHTTTHHHHHHHHH?TTS-----?HH-HHHHTT?-----BGG-------GT----B?SHHHHHHHHH---HHHHHHHTT?HHHHHHHH--HHHHHT?E-EEE-EE--?TTHHHHT 2OCE|A PF09374.5_PG_binding_3_seed 20 106 !Q:10,15|17,21|23,25|27,29|37,44|48,48|82,84 Q:0,9|16,16|22,22|26,26|30,36|45,47|49,81|85,105 HHHHHHHHHH------T-----S???S???HHHHHHH--------HHS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS???HHHHHHHSTHHHHHHHHHHHH 2NR7|A PF09375.5_Peptidase_M75_seed 169 599 !Q:5,9|24,26|32,33|39,53|55,55|60,61|81,137|140,150|159,191|199,209|212,218|221,222|235,305|308,308|310,311|331,379|382,383|387,389|396,396|405,405|408,429|431,431|437,438|446,446|456,470|476,476|479,482|486,486|489,490|492,495|507,512|521,521|523,531|535,535|537,552|557,560|568,578|582,586|595,595 Q:0,4|10,23|27,31|34,38|54,54|56,59|62,80|138,139|151,158|192,198|210,211|219,220|223,234|306,307|309,309|312,330|380,381|384,386|390,395|397,404|406,407|430,430|432,436|439,445|447,455|471,475|477,478|483,485|487,488|491,491|496,506|513,520|522,522|532,534|536,536|553,556|561,567|579,581|587,594|596,598 HHHHH-----HHHHHHHHHHHHHH---HHHHH--HHHHH---------------T?HHHH--HHTHHHHHHHHHHTHHHHT---------------------------------------------------------TS-----------HHHHHHHH??-------------------------------GGGSTTG-----------GG------?TT??SHHHHHHHHHTS?-----------------------?---------------------------------------------?TT?H--HHHHHHHHHHHHHHHHHHT??------?---------------------------------------?HH--HHH---HHHHHH-HHHHHHTS-TT----------------------S?TTTTT??HHHHHHH-HHHHHHHHH---------------HHHHH-HH----HHH-HH--H----HHHHHHHHHHH------HHHHHHTT-B?--------TTS?B?--------------?GGGS---?HHHHHHH-----------HHH-----HHHHHHHH-HHH 3OYV|A PF09376.5_NurA_seed 65 660 !Q:0,0|9,20|25,25|44,45|56,57|62,123|139,164|172,173|184,184|192,192|194,194|210,210|244,247|267,267|276,286|296,297|312,313|345,355|364,367|374,435|448,452|457,457|460,460|462,464|469,469|476,514|524,525|533,541|546,547|552,565|568,579|581,581|591,636|640,640|647,649 Q:1,8|21,24|26,43|46,55|58,61|124,138|165,171|174,183|185,191|193,193|195,209|211,243|248,266|268,275|287,295|298,311|314,344|356,363|368,373|436,447|453,456|458,459|461,461|465,468|470,475|515,523|526,532|542,545|548,551|566,567|580,580|582,590|637,639|641,646|650,659 ?EEEEEEEE------------EEEE-EETTEEEEEEEEEEEESS??EEEEEEEEEE??HHHH--------------------------------------------------------------HHHHHHHHHHHHHHH--------------------------HHHHHHT??SSSEEEEEES?TTHHHHS?S?TTHHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHSEES????HHHHHHHHHHHHTGGGEEE?SSSEEEEE???????????EEETHHHHH??SSBHHHHHHHHHTT??EEEEEHHHHHHHHHHHHHHHHHHHHHHHHTT?----------SSEEEEES????HHHHHH?-------------------------------------------------------??????HHHHHHHHHHHT?????EEEE?SS?B???GGGS?HHHHTT--------------------------------------?HHHHHHHHS?-BEEEEEE?--------SSSS??EEEE--------------ES------------S?HHHHHHHHH----------------------------------------------TTB?SSSBHH---HHHHHHHHHT 3TAI|A PF09377.5_SBDS_C_seed 27 234 !Q:15,16|20,20|23,23|32,32|38,84|89,90|105,106|109,110|114,116|121,121|131,189|197,198|201,203|207,208|212,213|217,219 Q:0,14|17,19|21,22|24,31|33,37|85,88|91,104|107,108|111,113|117,120|122,130|190,196|199,200|204,206|209,211|214,216|220,233 THHHHHHHHHHTTEE??TTS?TT?HHHHHHHH-HHHSS?----------------------------------------------SSTT??HHHHHHHHHHHHHH--HS??EEE???EEEE?BHHHHHHHT-----------------------------------------------------------TTHHHHT?-EE---EEE??SSB??EEE???GGGHHHHHHHHHHH 2KDO|A PF09378.5_HAS-barrel_seed 60 155 !Q:20,20|22,36|38,39|48,66|69,69|79,111|121,122|124,144|146,147|150,150 Q:0,19|21,21|37,37|40,47|67,68|70,78|112,120|123,123|145,145|148,149|151,154 SGGGEEEEEEEETTEEEEEE?T---------------T??TTEEEEET-------------------TS?EEEEEEEET---------------------------------TEEEEEESS??S---------------------S??TT?EEEE 3OAA|A PF09379.5_FERM_N_seed 30 147 !Q:2,3|7,8|14,18|22,22|25,25|38,38|40,43|51,51|53,67|70,71|77,77|79,80|82,88|90,90|93,94|96,98|106,106|110,110|116,133|145,147 Q:0,1|4,6|9,13|19,21|23,24|26,37|39,39|44,50|52,52|68,69|72,76|78,78|81,81|89,89|91,92|95,95|99,105|107,109|111,115|134,144 EE-?TTS?-EEEEE-----EEE?SS-HHHHHHHHHHHH-T????SSEEEEE-E??????------???SS??SSSSS?S??S?-----?S?SS??S???SSSEEEE?SSS?HHHHT??----------------TTSEEEEEESS??- 3BIN|A PF09380.5_FERM_C_seed 62 205 !Q:0,0|3,4|6,7|10,10|22,24|28,28|50,98|107,150|154,155|160,160|163,164|170,171|183,189|191,192|194,196|202,204 Q:1,2|5,5|8,9|11,21|25,27|29,49|99,106|151,153|156,159|161,162|165,169|172,182|190,190|193,193|197,201 ?TT??E--EE-EEEETTEEEEE---ETT?SSSEEEEEETTTEEEEEEETT-------------------------------------------------EEEEEETT--------------------------------------------TTS??EEEE?SS--HHHHH--HHHHHHHHHHH-------H--H---HHHHS??? 3BIN|A PF09381.5_Porin_OmpG_seed 4 301 !Q:0,26|41,41|44,44|46,48|77,78|81,83|99,99|118,118|121,121|124,125|158,158|160,160|165,167|198,198|203,204|207,207|217,218|238,238|245,248|250,253|264,264|280,281|286,286|300,300 Q:27,40|42,43|45,45|49,76|79,80|84,98|100,117|119,120|122,123|126,157|159,159|161,164|168,197|199,202|205,206|208,216|219,237|239,244|249,249|254,263|265,279|282,285|287,299 --------------------???????EEEEEEEEEEEEES?SS?S???EEEEEEEEEEEETTEEEEEEEEEEEESS??SS???SEEEEEEEEEEEEEE?SSSEEEEEEEEEEEEEEE?SS?TT??EEEEEEEEEEEEEEEESSSSEEEEEEEEEEEE?S?HHHH???SEEEEEEEEEEEEEETTEEEEEEEEEEEEE?SSSS??TT?EEEEEEEEE??EEETTEEEEEEEEEEEEEE?SSTTSS????S????EEEEEEEEEE?SSSEEEEEEEEEEEE??SSSS?EEEEEEEEEEEEE? 2IWW|A PF09382.5_RQC_seed 174 188 !Q:1,1|16,25|27,28|30,48|58,82|84,86|93,96|99,99|106,107|112,112|115,115|133,137|143,148|152,152|157,157|160,160|162,163|169,170|173,176|178,181|185,187 Q:0,0|2,15|26,26|29,29|49,57|83,83|87,92|97,98|100,105|108,111|113,114|116,132|138,142|149,151|153,156|158,159|161,161|164,168|171,172|177,177|182,184 E?HHHHHHHHHHHHHT----------T--T----?----------?--?HHHHHHHHH-------------------------T???HHHHHT----TG-GGSTTT--TTTT-TS?HHHHHHHHHHHHHTTSE-----EEEGG------GTT-EEEE?GG-G--HHHHT--TS----S--??EEE??? 2AXL|A PF09383.5_NIL_seed 184 94 !Q:11,11|13,13|16,16|26,29|31,32|57,62|64,65|67,67|71,72|82,82|86,87|90,90 Q:0,10|12,12|14,15|17,25|30,30|33,56|63,63|66,66|68,70|73,81|83,85|88,89|91,93 SSEEEEEEEES?S?SS?HHHHHHHHH----T-?EEEEEEEEEEEETTEEEEEEEEEE------E--S?HHH--HHHHHHHHH-HTT-?EE-EES 2QRR|A PF09385.5_HisK_N_seed 7 146 !Q:0,16|38,40|43,43|69,69|72,73|91,92|115,117|146,146 Q:17,37|41,42|44,68|70,71|74,90|93,114|118,145 ??-----------????HHHHHHHHTHHHHHHHHHTTS???TT?TTHHHHHHHHHHHHHHHHHHHTTSS?GG--GGHHHHHHHHHHHHHHT??THHHHHHHHHHHHHHHHHHHHT???HHHHHHHHHHHHHHHHHHHHHHHHHHHH- 3PMC|A PF09386.5_ParD_seed 4 79 !Q:0,0|8,8|25,25|36,38|53,53|55,57|60,61|63,64|68,72|76,78 Q:1,7|9,24|26,35|39,52|54,54|58,59|62,62|65,67|73,75 ?EEEEEEE?HHHHHHHHHHHHHHTS?HHHHHHHHTS???SSHHHHHHHHHHHS?S???SS??S??SSS?????SSS??? 2AN7|A PF09387.5_MRP_seed 11 227 !Q:0,29|40,41|48,49|52,52|56,58|71,74|80,81|83,84|86,86|90,106|109,112|114,114|121,121|136,136|138,139|143,143|153,153|157,157|160,160|168,188|191,195|200,200|222,226 Q:30,39|42,47|50,51|53,55|59,70|75,79|82,82|85,85|87,89|107,108|113,113|115,120|122,135|137,137|140,142|144,152|154,156|158,159|161,167|189,190|196,199|201,221 ??????????????????????????????SHHHHTTTSS??EEEEEE??SS?TTT?--EEEEEEEETTEE----EEEEE--E??S?SSS-----------------SS????E-EEEEEE?TTHHHHHHHHHHTS?S??EEE?SSEEEEEEE?SSS-TT?EEEEEEE?????-???????????-???EE-----EEEE?HHHHHHHHHHHHHHHHHHTTT????? 2GID|A PF09388.5_SpoOE-like_seed 47 46 !Q:20,21|46,46 Q:0,19|22,45 HHHHHHHHHHHHHHHHHHHT-?TTSHHHHHHHHHHHHHHHHHHHHH- 2C0S|A PF09390.5_DUF1999_seed 3 168 !Q:0,3|7,9|20,39|44,46|58,59|64,64|80,80|92,94|118,118|124,126|129,129|141,144|147,167 Q:4,6|10,19|40,43|47,57|60,63|65,79|81,91|95,117|119,123|127,128|130,140|145,146 ?---EEE???GGGHHHHHHT--------------------STTS???HHHHHHHHHHS??EEEE-ETTEEEEEEEEEEEE?SSSEEEEEEEE---EESSHHHHHHHHHHHHHHHHHTT?SEEEE???TT?HHHHHHHHHTT????SS????????????????????? 2D4P|A PF09391.5_DUF2000_seed 36 139 !Q:12,12|30,31|33,33|38,38|40,40|43,43|47,47|50,52|56,56|63,64|79,81|83,85|95,97|108,109|113,114|134,134|137,138 Q:0,11|13,29|32,32|34,37|39,39|41,42|44,46|48,49|53,55|57,62|65,78|82,82|86,94|98,107|110,112|115,133|135,136 SEEEEEEEETTS?HHHHHHHHHHHHHHHHH--H?GGGB?S?EE?TTS?EE???BSS?EEEEEE-?HHHHHHHHHHHHHT---T???EEEEGGGGG???HHHHHHHHTT??TTT??EEEEEEEEEHHHHHHHTTT?EE?? 2GAX|A PF09392.5_MxiH_seed 39 171 !Q:0,135|151,152|170,170 Q:136,150|153,169 ???????????????-----------------------------------------------???????????????--------------------------------------------------???---???HHHHHHHTTHHHHHT??HHHHHHHHHHHHHHHHT? 2JOW|A PF09393.5_DUF2001_seed 25 153 !Q:0,11|23,26|31,33|42,44|47,47|58,60|62,64|73,75|90,93|101,102|105,105|109,112|120,122|130,139|144,145|150,152 Q:12,22|27,30|34,41|45,46|48,57|61,61|65,72|76,89|94,100|103,104|106,108|113,119|123,129|140,143|146,149 ??-----?????EEEEEEEEEEE----TTEE???EEEEEEEE???SS?TTTTHHHHTS???S???EEEEEEES???HHHHHHHHHHHHTT????EEEEEEE??TT?SSS?--?EEEEEEE???HHHHHTT????-?????EEEE??SEEE??? 2GUJ|A PF09394.5_Inhibitor_I42_seed 103 131 !Q:3,5|8,9|16,18|21,22|25,25|32,39|46,49|51,58|60,60|62,63|65,65|68,74|79,80|83,83|89,89|91,95|97,100|110,110|116,119|126,126 Q:0,2|6,7|10,15|19,20|23,24|26,31|40,45|50,50|59,59|61,61|64,64|66,67|75,78|81,82|84,88|90,90|96,96|101,109|111,115|120,125|127,130 EEE--?TT?-EEEEEE???TT--TS?EEEEEE------??TTTEEE--??S------??S?S--S?SS??----?SSSS??EE-EEEEE?S?----E----EEEEEEEEE?TTSSS??-?SSEEEE-EEEE 3CBJ|B PF09396.5_Thrombin_light_seed 13 49 !Q:0,8|10,10|15,15|17,17|23,24|32,34|45,48 Q:9,9|11,14|16,16|18,22|25,31|35,44 ?????????S?HHHH?S?GGGTT??TTTGGGT???TTHHHHHHTT???? 3GIS|A PF09397.5_Ftsk_gamma_seed 130 72 !Q:0,0|3,3|6,6|33,34|52,55|58,58|64,64|66,70 Q:1,2|4,5|7,32|35,51|56,57|59,63|65,65|71,71 ?TT-TS?TTHHHHHHHHHHTTEEEHHHHHHHHT??HHHHHHHHHHHHHHTSB????SS-SEEEB?S---??S 2VE8|A PF09398.5_FOP_dimer_seed 6 85 !Q:0,6|18,20|37,37|50,56|66,69|76,76 Q:7,17|21,36|38,49|57,65|70,75|77,84 ?-?????HHHHHHHTSHH---HHHHHHHHHHHHHHTT?HHHHHHHHHHHT???????HHHHHHHTT????TTTTTS?HHHHHHHH 2D68|A PF09399.5_SARS_lipid_bind_seed 4 98 !Q:0,12|24,24|26,36|39,40|47,48|51,51|60,61|63,63|67,67|74,78|81,81|83,83|88,88|96,97 Q:13,23|25,25|37,38|41,46|49,50|52,59|62,62|64,66|68,73|79,80|82,82|84,87|89,95 --------?????EEEEEEEEEEE?S-----------SS??EEEEEE??SS?EEEEEEEE??S?SSS?SEEEEE?????EE?S?GGGS?SEEEEEE?? 2CME|A PF09400.5_DUF2002_seed 4 117 !Q:0,3|16,16|41,41|47,47|50,51|54,54|63,63|68,68|74,76|78,81|84,84|87,88|92,92|95,96|98,98|112,116 Q:4,15|17,40|42,46|48,49|52,53|55,62|64,67|69,73|77,77|82,83|85,86|89,91|93,94|97,97|99,111 ????HHHHHHHHHHTT?EEEEEETTEEEEEETTEEEEEETT?SSTTS?EE??SS?HHHHHHHS?BSSS?EEESS???S????SS-SS??EEE?EE??S?HHHHHHHHHHHHT????? 2G7J|A PF09401.5_NSP10_seed 11 125 !Q:0,1|27,34|37,39|41,41|43,45|51,54|66,66|73,82|98,98|106,107|109,109|113,113|120,124 Q:2,26|35,36|40,40|42,42|46,50|55,65|67,72|83,97|99,105|108,108|110,112|114,119 ??HHHHHHHHHTSSSHHHHHHHHHHTT????????BB???S?S???SEESS????TTEEEEESTTT?HHHHHT??????????TTTTSEEEEEGGGTT?HHHHHHH??B?TTT?SBTTBB????? 3R24|B PF09403.5_FadA_seed 3 133 !Q:0,28|91,91 Q:29,90|92,132 -------------------???------?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS?TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 3ETZ|A PF09404.5_DUF2003_seed 3 449 !Q:0,1|5,108|123,127|129,132|157,158|174,184|210,210|236,254|284,284|295,295|298,298|312,312|320,349|357,357|359,360|383,383|414,416|419,419|434,434|443,448 Q:2,4|109,122|128,128|133,156|159,173|185,209|211,235|255,283|285,294|296,297|299,311|313,319|350,356|358,358|361,382|384,413|417,418|420,433|435,442 ??SST--------------------------------------------------------------------------------------------------------TTTHHHHHHHHTTT?????S????THHHHHHHHHHHHHHHHHGGGSSS??HHHHHHHHSTTTGGG???????????HHHHHHHHHHHHHHHHHHHHHHTTT?HHHHHHHHHHHHHHHHHHHHHHHTT???????????????????HHHHHHHHHHHHHHHHHHHHTHHHHHHTS?HHHHHHHHHH?SS?HHHHHHHHHHHHT?SEEEEEE??????????????????????????????EEEEESS-S??GGGHHHHHHHHHHTHHHHHTSS?EEEEEEGGGTEEEEEEEEETTEEEEEEESS???TT?HHHHHHHHHHHHTT?HHHHHHTT?????? 2GNX|A PF09405.5_Btz_seed 21 183 !Q:0,152|154,182 Q:153,153 ?????????--???????????--????????????????????--???????????????????-?????------????--------------------------------------------------------????????---?????S???--???????????????????????? 2J0U|T PF09406.5_DUF2004_seed 22 116 !Q:17,20|23,25|46,46|49,52|54,55|72,72|74,74|89,98|102,102|106,106|108,109|115,115 Q:0,16|21,22|26,45|47,48|53,53|56,71|73,73|75,88|99,101|103,105|107,107|110,114 SSHHHHHHHHHHHHHHH?---TT???EEEEEEEEETTEEEEEEEEE?SS--??S??HHHHHHHHHHHHHHHH-S?HHHHHHHHHGGGGT??-???-???EEE?SSS?S??SHHHH? 2ABY|A PF09407.5_DUF2005_seed 2 315 !Q:1,19|22,22|25,25|27,31|45,46|63,66|83,83|92,93|96,96|101,101|113,113|116,118|121,121|131,132|135,137|144,145|148,151|162,166|169,169|175,176|185,186|195,195|197,198|209,209|213,215|230,231|243,243|259,259|270,270|272,272|274,277|281,281|284,291|313,314 Q:0,0|20,21|23,24|26,26|32,44|47,62|67,82|84,91|94,95|97,100|102,112|114,115|119,120|122,130|133,134|138,143|146,147|152,161|167,168|170,174|177,184|187,194|196,196|199,208|210,212|216,229|232,242|244,258|260,269|271,271|273,273|278,280|282,283|292,312 E-------------------EE?TT?S?????GGGHHHHHHHHHH??SSEEHHHHHHHHHHTT????HHHHHHHHHHHTSEEE?SSTTEEEE??TT?SEEE?TTHHHHHHHHH?TT???EE?HHHHHHHHT??SS???SSEEEE??TT????GGGTTTEEEE?????TT?HHHHS??HHHHHHTT??TTTTTTTS?B??HHHHHHHHHH?GGG???HHHHGGGHHHHHHT??HHHHHHHHTTS?HHHHHHHHHHHHHTT?HHHHHHHHTT?S?S????EEE?SS????????EEEGGGTEEESSHHHHHHHHH?? 1ZEL|A PF09408.5_Spike_rec_bind_seed 11 272 !Q:0,6|14,14|16,18|23,23|28,29|31,34|41,41|46,48|52,53|55,65|84,85|93,96|99,101|108,108|113,114|117,117|119,121|125,127|130,132|135,142|144,144|148,151|157,157|159,159|164,165|167,167|171,171|184,271 Q:7,13|15,15|19,22|24,27|30,30|35,40|42,45|49,51|54,54|66,83|86,92|97,98|102,107|109,112|115,116|118,118|122,124|128,129|133,134|143,143|145,147|152,156|158,158|160,163|166,166|168,170|172,183 ???????GGGGTTT?S???BSTT?EEEE??S????SHHHHS?TTBS???BSS??S???????????EEEEEEEETGGGGGSSSS??SSHHHHT????SS???EEEEEE?HHHH??TT?B???EEE???SS???TT????????B?TTS????TTTTT?B?SEEE??B?SSS?GGGSEEEEEEEE?????????????????-----?????????------------------------------?????--------------------?? 2GHV|C PF09409.5_PUB_seed 76 117 !Q:1,1|14,14|23,23|26,26|36,36|47,47|50,53|59,59|64,64|67,77|83,87|91,98|109,115 Q:0,0|2,13|15,22|24,25|27,35|37,46|48,49|54,58|60,63|65,66|78,82|88,90|99,108|116,116 S?HHHHHHHHHHHH-HHHHHHHH?TT?GGGGEEETT?HHHHHHTTTS-TT----HHHHH-HHHT?EE?----------SSEEE??---TTS-------?HHHHHHHHHH-------H 2D5U|A PF09411.5_PagL_seed 51 190 !Q:0,0|4,4|15,18|21,24|43,50|53,59|71,71|77,78|82,84|104,125|129,129|131,131|149,155|166,166|171,171|173,173|175,177|189,189 Q:1,3|5,14|19,20|25,42|51,52|60,70|72,76|79,81|85,103|126,128|130,130|132,148|156,165|167,170|172,172|174,174|178,188 ?TTS?EEEEEEEEEE????EE----EETTEEEEEEEEEEEEEE?-----??SS?------SSEEEEEEEEE-EEEEE??SSE---EEEEEEEEEEEEESSSEET----------------------TEE?S?SEEEEEEEEEEEEETTS?------EEEEEEEEEE?TTSS-T-T???EEEEEEEEEEE? 2ERV|A PF09412.5_XendoU_seed 40 373 !Q:0,1|3,3|17,21|24,38|44,44|47,49|54,68|70,70|76,76|82,82|86,89|104,105|107,112|115,118|121,122|136,136|154,160|162,162|170,170|180,180|182,196|198,198|207,207|212,222|224,229|238,239|243,249|256,258|262,269|271,271|273,273|284,293|296,300|305,305|307,308|323,323|326,331|334,334|351,352|354,356|360,364 Q:2,2|4,16|22,23|39,43|45,46|50,53|69,69|71,75|77,81|83,85|90,103|106,106|113,114|119,120|123,135|137,153|161,161|163,169|171,179|181,181|197,197|199,206|208,211|223,223|230,237|240,242|250,255|259,261|270,270|272,272|274,283|294,295|301,304|306,306|309,322|324,325|332,333|335,350|353,353|357,359|365,372 ??B?HHHHHHHHHHHHT?----TT???------------BTTTE-EE???SBSS????????????-??S?SEEEE?HHHHT-TTS----THHHHHHHHHHHHH??S-----?SS-???HH--HHHHHHHHHHHHT-TSHHHHHHHHHHHHTTS-------S?SSHHHHH-HHHHHHHHS?B??????-----???-B?HHHHHTTS?SSSS----------?S??????HHHHHHHH--HTT?------EEEEEE???SSS----????T-T?SEEEEEEEET----------TB-????EEEE?S??HHHHHHHHHHHHHT?SS------SE-EEEEEEETTEEEEEEE--E---EET-----TEEEEEEE 2C1W|A PF09413.5_DUF2007_seed 90 83 !Q:6,10|26,27|30,31|33,37|40,51|53,54|59,59|67,67|82,82 Q:0,5|11,25|28,29|32,32|38,39|52,52|55,58|60,66|68,81 EEEEEE??---HHHHHHHHHHHHHTT??EE??S??-??SS------------S??SSSS?EEEEEEG-GGHHHHHHHHHHTT? 2HFV|A PF09414.5_RNA_ligase_seed 22 341 !Q:1,1|8,9|23,28|41,46|49,51|57,73|91,92|97,97|99,105|119,129|133,137|141,141|145,145|152,153|155,157|160,162|179,180|186,189|191,192|206,206|208,211|213,215|227,228|232,232|234,264|271,297|299,299|303,304|307,308|310,311|322,322|328,330|332,335 Q:0,0|2,7|10,22|29,40|47,48|52,56|74,90|93,96|98,98|106,118|130,132|138,140|142,144|146,151|154,154|158,159|163,178|181,185|190,190|193,205|207,207|212,212|216,226|229,231|233,233|265,270|298,298|300,302|305,306|309,309|312,321|323,327|331,331|336,340 S?EEEEEE??SEEEEEEEEEETT------EEEEEEEETTEE?----?TT???TTGGG-----------------GHHHHHHHHHHHHHHHH--HHHT?S-----??SEEEEEEEEEEEE???--------TTS?????EEE?TTS?EEEGGG??S???SS???EEEEEEEEEEEEEESS??GGGEE----E??HHHHHHHHHTSTT?E----E???SEEESHHHHHT??GGG?B------------------------------?SHHHHT---------------------------T?TTS??TT-?B??EEEEEETTTT?HHHHT---T????EEEEE 1S68|A PF09415.5_CENP-X_seed 24 89 !Q:0,0|10,10|14,14|16,16|18,19|22,22|50,72|79,79 Q:1,9|11,13|15,15|17,17|20,21|23,49|73,78|80,88 ?SHHHHHHHT-TTS?S-S??EE?TTTHHHHHHHHHHHHHHHHHHHHHHHH???????????--------????HHHHHH-HHHHHHHHT 3VH6|D PF09416.5_UPF1_Zn_bind_seed 16 159 !Q:2,2|6,9|18,19|28,29|33,33|36,36|47,49|53,53|59,59|61,61|63,65|69,72|80,81|83,83|86,88|108,108|112,112|118,119|124,124|129,132|136,136|141,144|158,158 Q:0,1|3,5|10,17|20,27|30,32|34,35|37,46|50,52|54,58|60,60|62,62|66,68|73,79|82,82|84,85|89,107|109,111|113,117|120,123|125,128|133,135|137,140|145,157 TS?TTT????TTTEEEET--TTTEEEES??TTS-SS?HHHHHHHHTT???EEE?TTSTT?S?B???TTT????TTTEEEE??T-TS???EEEETTTTTSHHHHTTTSS?GGG?EESEE--TTEE?TTTS????HHH-HHHS????HHHHHHHHHHHHT? 2IYK|A PF09423.5_PhoD_seed 148 1030 !Q:1,1|6,8|11,11|15,46|50,54|57,80|86,89|92,94|103,105|107,115|121,129|131,132|140,140|143,143|146,147|154,179|183,183|185,202|205,205|213,215|217,223|225,226|230,232|237,242|245,253|260,263|265,274|276,276|278,299|308,311|313,318|324,324|326,326|329,332|335,339|342,343|346,354|356,357|359,366|368,370|373,391|400,403|410,410|419,422|429,431|439,439|441,443|447,461|465,466|486,502|506,511|515,515|517,552|566,567|572,617|620,620|626,688|691,691|694,724|727,728|731,731|744,750|752,756|764,764|767,768|770,772|775,775|778,833|835,836|844,854|868,870|872,875|878,878|880,882|888,888|902,916|919,920|924,926|928,928|935,941|946,946|948,950|954,965|971,971|976,977|985,985|987,1002|1007,1014|1018,1019 Q:0,0|2,5|9,10|12,14|47,49|55,56|81,85|90,91|95,102|106,106|116,120|130,130|133,139|141,142|144,145|148,153|180,182|184,184|203,204|206,212|216,216|224,224|227,229|233,236|243,244|254,259|264,264|275,275|277,277|300,307|312,312|319,323|325,325|327,328|333,334|340,341|344,345|355,355|358,358|367,367|371,372|392,399|404,409|411,418|423,428|432,438|440,440|444,446|462,464|467,485|503,505|512,514|516,516|553,565|568,571|618,619|621,625|689,690|692,693|725,726|729,730|732,743|751,751|757,763|765,766|769,769|773,774|776,777|834,834|837,843|855,867|871,871|876,877|879,879|883,887|889,901|917,918|921,923|927,927|929,934|942,945|947,947|951,953|966,970|972,975|978,984|986,986|1003,1006|1015,1017|1020,1029 T?EEEE???SS?EEE--------------------------------EEE---??SB------------------------GGGTB???-SS--?EEEEEEEE---S---------STTSS---------S--EEEEEEE-EE?GG--GTTEEE--------------------------EEE?S----------------??TT?EEEEEEE---E-------T--TEE???EEEE??-?-?TT?????----EEEEEE????G----------G-G??-------------------?HHHHHHTT----S-?---?SEEEE?S?SS????TT-----SS??TT----??--?S??S--------S---SS-----------------??SHHHHHHH----HHHHHT?HHHHHHHH----HSEEEE???STTTSTT?B---TTB?--------------STT??HHHHHHHHHHHHHHHHHHS??------------?--GGG?----?BTT-B---------------------??-?----------?EEEEETTTEEEEE??SSSS??------------------------------------------??GG-GSSEE?------------------------------------------------------------??HH-HH--------------------------?----TT??SS?HHHHHHHHHHHH-------H??---SSEEEEE?SS??S???SS?SS--------------------------------------------------------S??EETTSGG-----------GSHHHHHHHHHHH---H----HT-T???EEEEE?SSSSEEEEEEESS---------------TT?-TTS?--E-EEEEEE???----SSTT?S--?BSB-----------?TTHHH-HHHH-?TTEEEEE-B?---------------EEEE--------EEE--EETTEEEEEE 2YEQ|A PF09424.5_YqeY_seed 42 157 !Q:15,15|39,41|43,46|73,73|92,96|112,114|116,122|143,144|156,156 Q:0,14|16,38|42,42|47,72|74,91|97,111|115,115|123,142|145,155 HHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHTTS---S?-??HHHHHHHHHHHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHGGGS?????HHHHHHHHHHHHHHT---T??-----SGGGHHHHHHHHHHHHTTTS-?HHHHHHHHHHH? 1NG6|A PF09425.5_CCT_2_seed 18 34 !Q:0,8|19,33 Q:9,18 ---?----?TTHHHHHHHH??????---????-- 3OGL|Q PF09426.5_Nyv1_N_seed 5 156 !Q:0,0|11,13|16,17|19,21|23,23|28,28|30,31|38,44|60,63|66,66|71,72|74,75|84,88|91,91|105,105|121,129 Q:1,10|14,15|18,18|22,22|24,27|29,29|32,37|45,59|64,65|67,70|73,73|76,83|89,90|92,104|106,120|130,155 ?SEEEEEESSS???EE--E???S-SSSS?S??SSTTSS?-----?HHHHHHHHHHTTGGG????SS?SSEE??S??SSSEEEEE??--?SS?TTEEEEEEEETTS?SSHHHHHHHHHTTSS??------?STTTHHHHHHHHHHHHHHHHHHTTTS 2FZ0|A PF09439.5_SRPRB_seed 8 203 !Q:0,3|9,9|26,30|32,34|36,38|40,40|42,42|49,54|59,59|64,67|97,97|100,101|122,124|131,131|137,139|164,179|181,184|186,193|200,201 Q:4,8|10,25|31,31|35,35|39,39|41,41|43,48|55,58|60,63|68,96|98,99|102,121|125,130|132,136|140,163|180,180|185,185|194,199|202,202 ????EEEEE?STTSSHHHHHHHHHHS-----S???B???S-S?EEETTG------GGSS?EEEE????GGGTHHHHHHHHHHGGGEEEEEEEEETTS?TT??HHHHHHHHHHHHHHHHHSTT???EEEEEE?TTSTT???HHHHHHHHHHHHHHHHHHHHHHHH????????????????T----T????????GGGSSS?-E 1KSG|A PF09442.5_DUF2018_seed 14 92 !Q:2,3|16,16|42,42|44,44|47,52|64,64|89,91 Q:0,1|4,15|17,41|43,43|45,46|53,63|65,88 SS??HHHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHHHHHHT-T?HH------HHHHHHHSTTT?SHHHHHHHHHHHHHHHHHHHHHHH??? 2BO3|A PF09443.5_CFC_seed 9 37 !Q:1,6|9,9|12,20|24,25|27,28|35,36 Q:0,0|7,8|10,11|21,23|26,26|29,34 S??-???TT?SS?????????SSS??S??SSSSTT?? 2J5H|A PF09445.5_Methyltransf_15_seed 11 300 !Q:0,0|8,8|21,23|25,25|33,33|49,50|60,60|64,106|111,120|126,129|141,141|145,145|147,147|150,151|159,170|175,175|177,177|180,182|190,190|195,247|251,254|256,256|259,260|263,279|297,299 Q:1,7|9,20|24,24|26,32|34,48|51,59|61,63|107,110|121,125|130,140|142,144|146,146|148,149|152,158|171,174|176,176|178,179|183,189|191,194|248,250|255,255|257,258|261,262|280,296 ?SEEEETT?TTSHHHHHHHHT---T?EEEEEES?HHHHHHHHHHHHHTT?-GGGEEEEES?HHH-------------------------------------------HGGG??-------?SEEEE????SSGGGGGSSSB?TTT-S?SS-?HHHHHHH------------HHHH?S?EE---EEEETTB?HHHH-----------------------------------------------------HHT----T?TT??EE-----------------EEEEEETTEEEEEEEEE??? 3AY0|A PF09448.5_MmlI_seed 3 112 !Q:7,9|12,13|31,31|34,35|45,52|54,60|79,79|94,98|105,111 Q:0,6|10,11|14,30|32,33|36,44|53,53|61,78|80,93|99,104 EEEEEEE???TT??HHHHHHHHHHHHHHHTT?TT??EEEEEEEEE????????B???????EEEEEEESSHHHHHHHHH?HHHHHHHHHHHHHT?????EEEEES??????? 3HFK|A PF09449.5_DUF2020_seed 4 144 !Q:0,1|4,8|14,18|22,22|31,31|33,35|46,46|52,52|57,57|66,66|81,81|89,90|94,94|101,102|126,126|143,143 Q:2,3|9,13|19,21|23,30|32,32|36,45|47,51|53,56|58,65|67,80|82,88|91,93|95,100|103,125|127,142 ??TT?????TTGGG?????TTS?HHHHHHHH?S???EEEEETTSSS?EEEEE?SSSS?SEEEEEEE?SSHHHHHHHHHHHS?TTTSEEE??STT?EEEEEE--ETTEEEEEEEETTEEEEEEESSS?HHHHHHHHHHHHHHHT? 3V7B|A PF09450.5_DUF2019_seed 7 106 !Q:22,22|46,46|59,59|74,74|90,90 Q:0,21|23,45|47,58|60,73|75,89|91,105 HHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHSTT?GGGGGGGGGGSS?HHHHHHHHHTTTTT?HHHHHHHHHHHHHHT?TTHHHHHHHHHHHHH 2I9C|A PF09452.5_Mvb12_seed 4 97 !Q:5,6|14,15|17,34|74,97 Q:0,4|7,13|16,16|35,73 HHHHS??EESSSTT--S??????????????????HHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHS??---------------------- 2P22|D PF09453.5_HIRA_B_seed 30 24 !Q:0,2|6,6|10,10|14,15|20,23 Q:3,5|7,9|11,13|16,19 ???EEE?TTS?EEE??EEEE???? 2I32|E PF09454.5_Vps23_core_seed 19 65 !Q:5,5|40,40 Q:0,4|6,39|41,64 GGTEE?SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSS?HHHHHHHHHHHHHHHHHHHHHHHH 2P22|A PF09455.5_Cas_DxTHG_seed 44 657 !Q:7,7|10,21|23,25|35,49|53,56|68,75|86,97|101,102|112,116|126,127|148,148|163,164|172,174|177,177|180,199|202,202|205,205|213,215|221,221|225,226|228,235|247,248|253,253|267,290|296,296|305,317|319,320|327,327|334,336|339,348|351,351|357,398|407,407|415,426|450,450|454,454|460,467|469,471|491,492|494,494|496,496|501,518|528,528|567,567|574,574|577,579|586,612|616,617|628,644|655,656 Q:0,6|8,9|22,22|26,34|50,52|57,67|76,85|98,100|103,111|117,125|128,147|149,162|165,171|175,176|178,179|200,201|203,204|206,212|216,220|222,224|227,227|236,246|249,252|254,266|291,295|297,304|318,318|321,326|328,333|337,338|349,350|352,356|399,406|408,414|427,449|451,453|455,459|468,468|472,490|493,493|495,495|497,500|519,527|529,566|568,573|575,576|580,585|613,615|618,627|645,654 EEEEEES?GG------------G???EEEEETTEE---------------EEE----SSSHHHHHHHH?------?SEEEEEEEGG------------GTT??BTTTTBSSS?????SSHHHHHHH--HHHHHHHHHHHTTTGGGGGT?HHHHHHHHHHHHTT--SEEEEEE???EE?SS?-------------------EE-ES?THHHHHH---HHHHH-HHH--S?-----??TTEEEEEEEEE??SSHH-HHHHHHHHHHHHH------------------------HTTTS?EEEEEEEE??--------???S??HHHHHS?EEEEEE???EE??????????TT?HHHHH------------------------------------------HHHHHHHT?HHHHHHS??---------?HHHHHHHHHHHHHHHHTTEEEEE?TTS?EEEEE-------?S???HHHHHHHHHHHHHHHHTTT??S?S?SSEE------------------HHHHHHHHG-GGGGSHHHHHHHHHHHHHHHHHHHEEEEEETTEEEEEE?HHHHHH?TT???HHHHHH---------------------------HHT??EEHHHHHHSS?????????????????HHHHHHHTTT?? 2I71|A PF09456.5_RcsC_seed 12 93 !Q:5,7|23,23|28,28|30,30|32,35|38,38|45,46|48,51|62,62|66,67|69,69|78,78|80,80 Q:0,4|8,22|24,27|29,29|31,31|36,37|39,44|47,47|52,61|63,65|68,68|70,77|79,79|81,92 EEEEE???HHHHHHHHHHHHTTT?EEEE?S-S????TT?EEEEES??S????SSEEEEEESS?SSS??S?STTEEEEE?S?TTHHHHHHHHHT 2AYY|A PF09457.5_RBD-FIP_seed 19 48 !Q:0,0|40,40 Q:1,39|41,47 ?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?GGGGBSS 2K6S|A PF09458.5_H_lectin_seed 87 89 !Q:8,8|10,10|12,13|16,19|30,31|33,33|36,43|45,50|58,58|64,64|70,70|73,75|87,88 Q:0,7|9,9|11,11|14,15|20,29|32,32|34,35|44,44|51,57|59,63|65,69|71,72|76,86 EEEEEEEE?S-S??SS--??EEEEEEEEEE--E?TT--------S??--??EEEEEEE?SSEEE-EEEEE?TT?-?EEEEEEEEEEE?? 2VMD|A PF09459.5_EB_dh_seed 49 617 !Q:0,0|6,9|11,11|17,21|24,25|33,76|82,84|86,90|99,99|104,104|112,204|206,241|245,248|255,282|284,291|295,296|298,299|302,325|328,328|331,364|367,367|371,372|378,466|468,468|471,471|476,498|501,501|505,506|511,511|515,540|543,545|550,552|555,556|560,563|574,576|578,579|581,583|585,588|590,590|602,605|610,611|614,614 Q:1,5|10,10|12,16|22,23|26,32|77,81|85,85|91,98|100,103|105,111|205,205|242,244|249,254|283,283|292,294|297,297|300,301|326,327|329,330|365,366|368,370|373,377|467,467|469,470|472,475|499,500|502,504|507,510|512,514|541,542|546,549|553,554|557,559|564,573|577,577|580,580|584,584|589,589|591,601|606,609|612,613|615,616 ?HHHHT----S?EEEEE?----EE??GGGGTTT-------------------------------------------?TTGGG-??S?????EEEEEEEE?SSEE-EEEEEEE?-?---------------------------------------------------------------------------------------???S?-------------------?---------------STT????EEEEEE----------------------------E--------SST--T??GG------------------------GT?BT----------------------------------TB?EEE--EEEET-----------------------------------------------------------------------------------------T?SS?EEEE-----------------------ES-STT--SEEE?GGG--------------------------GG???EEEE---EE--ETT----EEEEEEEEES???T--T---S????T-TEEEEEEEEEE---?GGGT??TT?SE 2IVF|C PF09460.5_Saf-Nte_pilin_seed 4 146 !Q:0,0|17,17|19,22|29,29|32,32|37,38|41,41|50,50|53,54|61,62|68,68|73,73|79,79|83,84|91,91|98,98|116,116|123,123|126,127|130,130|145,146 Q:1,16|18,18|23,28|30,31|33,36|39,40|42,49|51,52|55,60|63,67|69,72|74,78|80,82|85,90|92,97|99,115|117,122|124,125|128,129|131,144 ?EEEEEEEEEEEEEEEB?S????EEEEEE?TT?BSEE??TT?EEEEEEEE?SS??EEEEEE--ESSEE?STTS?EEEEE?TTT??EEEEEE?HHHHHT?SEEEEETTEEEEEEETT?EEEEEE?SS??EE?SEEEEEEEEEEEEE?- 2CO6|A PF09461.5_PcF_seed 5 46 !Q:0,6|10,11|42,42|45,46 Q:7,9|12,41|43,44 ?????-?SSS??TTSHHHHHHHHHHHHSSSSSSTHHHHHHHS?SS?- 2BIC|A PF09465.5_LBR_tudor_seed 5 55 !Q:0,0|6,6|9,9|15,15|20,20|44,44 Q:1,5|7,8|10,14|16,19|21,43|45,54 ?SSSSS?SS?EEEEE?TTSS?EEEEEEEEEETTTTEEEEEETTS?EEEEEGGGEE 2L8D|A PF09466.5_Yqai_seed 2 72 !Q:0,3|6,16|18,21|24,24|26,28|33,33|35,35|39,39|43,43|62,64|67,69 Q:4,5|17,17|22,23|25,25|29,32|34,34|36,38|40,42|44,61|65,66|70,71 ????SS?????-----?S????SS?B??-TTSS?B?TTS?EEE-ETTEEEEHHHHHHHHHHT???EE???SS 2DSM|A PF09467.5_Yopt_seed 2 71 !Q:0,0|18,18|38,38|45,45|49,49|68,70 Q:1,17|19,37|39,44|46,48|50,67 ?EEEEEEEEEEEEEEEEE?SSHHHHHHHHHHHHHTTTT?SEEEEE?TTS?EEEEEEEEEEEEEEEEEE??? 2DLB|A PF09468.5_RNase_H2-Ydr279_seed 42 542 !Q:0,3|7,11|19,27|34,35|38,38|42,42|48,50|64,89|92,92|98,126|133,134|141,142|155,213|219,229|241,272|291,293|295,295|300,398|412,412|425,541 Q:4,6|12,18|28,33|36,37|39,41|43,47|51,63|90,91|93,97|127,132|135,140|143,154|214,218|230,240|273,290|294,294|296,299|399,411|413,424 ?--?EEE-----EEEGGGG?????????EEEEEE??SS-SSS?EEEEE---ETTTTEEEEEEEE??------------------------SS?EEEES-----------------------------SEEEES??EEEEEE??HHHHHGGGTTTT??-----------------------???????????-----??????-----------?HHHHH----------?STTHHHHHTTT????---------------?????--??????HHHHHHHHHHHHHHHHHH---H-HHTT??????????????---------------------------------------------------------------------------??????????THHHHHHHHHHTT?GGGSSSSSSTTT???----------????????-------------------????????????????????-----------???????????????--??????----???????????--?????? 3P56|B PF09469.5_Cobl_seed 4 92 !Q:8,9|18,18|21,23|25,26|30,30|36,36|44,91 Q:0,7|10,17|19,20|24,24|27,29|31,35|37,43 HHHHHHTT??TTSEEEES?SS???B??TTS?HHHHT?SEEEEEE??-------------???????-------------------------- 2DAJ|A PF09470.5_Telethonin_seed 3 167 !Q:0,2|62,63|76,77|84,166 Q:3,61|64,75|78,83 ???EEEEEEEEEEETTTTEEEEEEEEEEEEEEEEEEEEEEEEEETTTTEEEEEEEEEEEEEE??TTTEEEEEETTS??EEEESS??????????????????????????????????????????????????????????????????????????????????? 1YA5|T PF09471.5_Peptidase_M64_seed 14 320 !Q:9,10|25,25|34,35|49,52|54,56|58,58|64,64|69,76|83,83|85,86|100,101|122,122|139,142|146,154|156,158|166,169|172,173|176,176|180,180|184,185|187,189|198,208|210,212|215,216|220,226|232,232|235,236|244,251|261,261|277,282|286,292|294,294|298,299|304,304|306,306|313,317 Q:0,8|11,24|26,33|36,48|53,53|57,57|59,63|65,68|77,82|84,84|87,99|102,121|123,138|143,145|155,155|159,165|170,171|174,175|177,179|181,183|186,186|190,197|209,209|213,214|217,219|227,231|233,234|237,243|252,260|262,276|283,285|293,293|295,297|300,303|305,305|307,312|318,319 HTTSGGGGT??EEEEEEEEEEEESS?EEEEEEEE-?TTSSEEEEEEEEE?---T---T?TTSEE?SSSS???-----EEEEEE?S?-TTTSEEEEEEEES??GGGHHHHHHHHHHHHHHHTT-STTTTTTGGGEEEEEE????SSS---------S?--BBGGGTB????TT??BS?BTT-BTT??B???HHHHHHHH-----------T---TS??SEE-------EEEES?SS??EEEETTT--------EEEEESSST-THHHHHHHHHHHHTT??????EES???????S?TTS??SSTT?B?SSSGGG-----TT 4DF9|A PF09475.5_Dot_icm_IcmQ_seed 21 185 !Q:13,13|17,17|42,43|55,55|65,65|74,74|77,77|79,79|90,96|98,98|102,102|113,113|127,127|132,135|139,140|142,142|146,146|148,148|150,150|152,152|155,158|160,162|166,166|169,169|172,172|174,174|178,181|183,184 Q:0,12|14,16|18,41|44,54|56,64|66,73|75,76|78,78|80,89|97,97|99,101|103,112|114,126|128,131|136,138|141,141|143,145|147,147|149,149|151,151|153,154|159,159|163,165|167,168|170,171|173,173|175,177|182,182 HHHHHHHHHHHHS?TTS?HHHHHHHHHHHHHHHHHHHHHHTH--HHHHHHHHHHH-HHHHHHTTT?EEEEEEEE?SS?S?TTTTHHHHTT???????S?EES?HHHHHHHHHH?SSSSSEEEEEEEE?SSSB????TTT??B?SSS?B?B?B?SS????S???EEE?SS?EE?B?SSS---?B?? 3FXE|A PF09477.5_Type_III_YscG_seed 7 118 !Q:0,3|20,20|36,37|54,54|59,60|68,69|85,85|99,101|116,117 Q:4,19|21,35|38,53|55,58|61,67|70,84|86,98|102,115 ????HHHHHHHHHHHHHTTT?HHHHHHHHHHHHHTT?-HHHHHHHHHHHHHHTT?HHHH--HHHHTTS??GGGHHHHHHHHHHHT?HHHHHHHHHHHTT???HHHHHHHHHHHHHH?? 2P58|C PF09479.5_Flg_new_seed 74 54 !Q:0,0|2,3|5,7|10,10|16,16|22,22|25,26|28,29|32,33|35,39|42,42|52,53 Q:1,1|4,4|8,9|11,15|17,21|23,24|27,27|30,31|34,34|40,41|43,51 ?E--E---TT-EEEEE-EESSS-SS??B??TT--T????-SS?EEEEEEEEE?? 2Y5P|A PF09480.5_PrgH_seed 8 416 !Q:0,198|204,209|215,215|219,219|250,250|269,270|276,276|282,282|286,286|292,295|310,310|313,313|315,316|322,322|339,340|357,359|378,378|389,415 Q:199,203|210,214|216,218|220,249|251,268|271,275|277,281|283,285|287,291|296,309|311,312|314,314|317,321|323,338|341,356|360,377|379,388 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------???--????HHHHH??????EEEEE?TTS?EEEEESSHHHHHHHHHHHHTSTTTTTEEEE?HHHHHHHHHHHHHHHSTT??EEEEE?SSTTS?EEE-EETTT????HHHHHHHHHHHHHH?TT?S??EEEEE?HHHHHHHHHHHHHHTT??EEEEEETTEEEEEEEE???HHHHHHHHHHHHHHHHHH?SSSEEEEEEE??????????????????????????? 2Y9J|A PF09481.5_CRISPR_Cse1_seed 55 752 !Q:6,6|11,17|21,22|28,28|35,38|43,43|47,48|50,50|60,61|67,69|74,103|106,112|114,114|117,118|127,136|139,140|151,152|157,157|161,161|164,167|171,171|175,186|190,190|196,210|213,238|240,243|258,263|271,281|286,288|294,294|298,307|310,310|321,342|345,359|364,367|375,376|380,385|387,388|395,397|404,407|409,409|413,425|434,438|442,443|445,461|464,465|468,479|481,481|485,485|489,495|499,499|513,513|515,520|524,530|545,579|591,592|595,595|598,598|609,609|614,622|657,657|659,668|681,688|705,705|714,727|738,741 Q:0,5|7,10|18,20|23,27|29,34|39,42|44,46|49,49|51,59|62,66|70,73|104,105|113,113|115,116|119,126|137,138|141,150|153,156|158,160|162,163|168,170|172,174|187,189|191,195|211,212|239,239|244,257|264,270|282,285|289,293|295,297|308,309|311,320|343,344|360,363|368,374|377,379|386,386|389,394|398,403|408,408|410,412|426,433|439,441|444,444|462,463|466,467|480,480|482,484|486,488|496,498|500,512|514,514|521,523|531,544|580,590|593,594|596,597|599,608|610,613|623,656|658,658|669,680|689,704|706,713|728,737|742,751 ETTTSS?EEEE-------ETT--EEEEE?HHHHHH----TGGG?SEE??S?HHHHHHHHH--HHHHH---HHHH------------------------------HT??----?S-HH--HHHHHHHH----------TS??HHHHHHHHHH--HGGG?EEE?SS--??TTS?TTS?-----------SSS?EEGGG---------------GS???---?????????-??????????B---?HHHHHHHHHHHHHH???---EEEEETT-----------EEEE???TTSSS?EEE----------EE?SSHHHHHHHH?????----------------?TT?------------??GGGS????HHHHGGG??EEE------S??HHHHHT???EEEEEE----E?SSS-------------EEEEEEEE??---EEE??S-------------??-?TT??EE------------E?SSS?EEE??---??SSS?GGGGTTTTSGGGT?B?----?HHH-------HHHHHHHHHHHHTT????-------------------------------EEEEEEEEEEE--TT-EE-EEEEEEEEEE?TTTT---------SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?S??-???????HHHHHHHHHHHS--------SHHHHHHHHHHHHHHH-HHTTTTSS--------------THHHHHHHHH----HHHHHHHHHH 4F3E|A PF09485.5_CRISPR_Cse2_seed 58 246 !Q:11,29|34,35|42,46|51,59|80,81|83,113|115,115|118,118|121,127|137,137|140,154|167,167|169,177|195,196|200,202|204,204|221,232|246,246 Q:0,10|30,33|36,41|47,50|60,79|82,82|114,114|116,117|119,120|128,136|138,139|155,166|168,168|178,194|197,199|203,203|205,220|233,245 HHHHHHHHHTT????----------?????HHHH??HHHHHT?????TTHH---------HHHHHHHHHHHHHHHHHHTT??S-------------------------------S?SB?TT?-----?HHHHHHTTS?TT???------------HHHHHHHHHHTT?S---------SHHHHHHHHHHHHHHHH--HTT??-B?HHHHHHHHHHTTSHHH------------HHHHHHHHHHHHH- 4H79|A PF09488.5_Osmo_MPGsynth_seed 15 526 !Q:2,5|16,18|24,25|27,45|49,50|70,71|83,83|87,87|93,96|99,99|101,101|118,120|128,128|140,141|145,145|150,154|156,157|173,174|177,177|183,184|186,186|189,189|207,222|232,251|271,287|290,290|303,304|326,327|329,329|339,389|397,397|400,402|404,408|412,412|427,460|464,474|486,490|497,497|500,507|510,511|516,516 Q:0,1|6,15|19,23|26,26|46,48|51,69|72,82|84,86|88,92|97,98|100,100|102,117|121,127|129,139|142,144|146,149|155,155|158,172|175,176|178,182|185,185|187,188|190,206|223,231|252,270|288,289|291,302|305,325|328,328|330,338|390,396|398,399|403,403|409,411|413,426|461,463|475,485|491,496|498,499|508,509|512,515|517,525 EE????EEEETTEEEE-??EEEEE--S???--------????????EEE??HHHHHHHHTTEEEEEEESS??HHHHHHHHHHS?TTS?EEEEE????SS-S?HHHHHHHHHHHHHHHH???EEEEETT?HHHHHHHHHHT??TTB?TTSS-----B??SHHHHHHHHHHHHHH--TT?SEEEE??S?BS?HHHHHHHHHHHHHHHHH?--------------?SSSEEEEEE???????????-????????HHHHHHHHHHHHHHHHHSS???----------????TT?SSEEEEHHHHTT??EESGGGHHHHHHHHHHHHHSS??S?GGGHHHHHH?--------------------------------------------------EEEEEEE?SS???B?-???HHH-HHHHHHHHHHHHHT----------------------------------STT??---------HHHHHHHHHHH-----HHTTSS?TT-???????EE??STTS?HHHHHHHHH 2ZU9|A PF09491.5_RE_AlwI_seed 18 668 !Q:8,16|19,21|27,27|36,52|55,57|70,71|74,74|78,78|83,83|87,90|93,93|106,116|118,118|120,120|131,132|134,136|147,156|168,168|177,189|202,223|225,238|249,308|329,334|343,343|348,348|358,367|369,370|382,382|385,385|387,388|391,391|418,418|438,441|487,487|495,500|505,505|508,508|523,523|526,528|534,537|541,541|545,545|549,551|553,554|557,557|563,569|579,582|588,590|613,615|626,627|638,648|653,655 Q:0,7|17,18|22,26|28,35|53,54|58,69|72,73|75,77|79,82|84,86|91,92|94,105|117,117|119,119|121,130|133,133|137,146|157,167|169,176|190,201|224,224|239,248|309,328|335,342|344,347|349,357|368,368|371,381|383,384|386,386|389,390|392,417|419,437|442,486|488,494|501,504|506,507|509,522|524,525|529,533|538,540|542,544|546,548|552,552|555,556|558,562|570,578|583,587|591,612|616,625|628,637|649,652|656,667 HHTTSEEE?--------TT---SBEEE?HHHHHHHT-----------------TS---SHHHHHHHHHHH??BS?SSS?TTSS?TTT---?BB?HHHHHHHHHHHH-----------S?B?HHHHHHHTTT??B---GGGHHHHHHH----------HHHHHHHHHHS?SHHHHHHH-------------HHHHHHHHHHHH----------------------S??????????????HHHHHHHHHH------------------------------------------------------------HHHHHHHHHHHHHHHTTSEE------EETTEEEE?GGGH-HHHHHHHHH???----?--S??SSHHHHHHHHT?TT?S??TT?SHHHHHHHHHHHHHHHHHHHHHHTTT?GGGHHHHHHHHHHHHHHHH-???HHHHHHHHHHHHHHHHHHHHHHHHHHTTSHHHHHHHHHHHHHTTS?HHHHHHH------HHTT?SS?HHHHHHHHHHHHHH-HH???SEEEE---?SEE?TTS?EEE???T--TS?SEEEE------?SSEEEEEEE????HHHHH---HHHHHHHHHHHHHHHHHHHHTT???EEEEEEEESS??HHHHHHHHHH-----------HHHH???EEEEEHHHHHHH 2EWF|A PF09492.5_Pec_lyase_seed 51 400 !Q:0,1|5,7|10,17|21,24|27,28|31,52|58,58|78,86|90,90|109,109|111,111|114,115|118,136|140,143|145,151|158,158|177,177|180,181|183,184|187,188|211,212|215,216|220,221|223,226|230,230|234,234|237,239|243,244|246,246|265,269|285,286|289,322|325,326|332,332|336,356|358,358|361,361|366,372|376,376|381,381|389,390 Q:2,4|8,9|18,20|25,26|29,30|53,57|59,77|87,89|91,108|110,110|112,113|116,117|137,139|144,144|152,157|159,176|178,179|182,182|185,186|189,210|213,214|217,219|222,222|227,229|231,233|235,236|240,242|245,245|247,264|270,284|287,288|323,324|327,331|333,335|357,357|359,360|362,365|373,375|377,380|382,388|391,399 ??TTS???SS------??SSS????TT??SS??????????????????????SSSSB?GGGTTHHHHHHHHHHHHHS--------?GGG?HHHHHHHHHHHHHHHHHS?T-TS??BS-------------------BSS?-??G-------GGGSEE?GGGHHHHHHHHHHHHHHT?TT?-T--TS?-HHHHHHHHHHHHHHHHHHHHHS?-EE--TTE--E????SEE?TTT?SB???STT??S?EEHHHHHHHHHHHTTSSS??---HHHHHHHHHHHHHHH--HS????????????------------???????-??SS??EESEE?SSS?-------------------?B?EE?TTSE-------EES?GGGS?HHHHSSS??EESTTHHHH 1GXM|A PF09496.5_CENP-O_seed 28 135 !Q:5,6|15,17|25,25|31,50|58,60|64,64|73,73|77,102|104,106 Q:0,4|7,14|18,24|26,30|51,57|61,63|65,72|74,76|103,103|107,134 EEEEE??EEETTEEE???EEEEEEE?SSSTT--------------------SEEEEEE???SSS?HHHHHHHH-HTT--------------------------T???HHHHHHHHHHHHHHHHHHHHHHHHHHTT 3ZXU|A PF09500.5_YiiD_Cterm_seed 47 169 !Q:11,11|19,19|33,34|40,40|46,46|71,74|86,86|88,90|92,94|100,122|124,126|133,134|150,156|168,168 Q:0,10|12,18|20,32|35,39|41,45|47,70|75,85|87,87|91,91|95,99|123,123|127,132|135,149|157,167 HHHHHHHHHHH?HHHHHTT?EEEEEETTEEEEE??SGGGB?TTSSB?HHHHHHHHHHHHHHHHHHHHHHHT??-?EEEEEEEEEEE?S???S?-?EEEEE??---------------------S???GGGGGT??EEEEEEEEEEETTEE-------EEEEEEEEEEE? 1SH8|A PF09507.5_CDC27_seed 21 625 !Q:0,1|13,14|36,36|38,38|58,108|124,124|139,140|157,157|161,161|166,166|170,170|173,173|176,624 Q:2,12|15,35|37,37|39,57|109,123|125,138|141,156|158,160|162,165|167,169|171,172|174,175 ??EEHHHHHHHHT??HHHHHHHHHHHHHHHHHHHSS?S?EEEEEEEEEEESSSSEEEE---------------------------------------------------EEEEETTTHHHHHHH?SEEEEEEEEEEESS??SSSTHHHHHHHHHHHH-HTT?GGGS?SEE?TT?SS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?-------------------------------?--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3E0J|B PF09508.5_Lact_bio_phlase_seed 7 779 !Q:0,0|6,7|10,10|23,23|28,36|42,43|50,50|55,55|62,62|67,67|73,75|78,78|84,84|93,93|100,101|104,104|109,109|117,118|121,121|128,128|139,140|143,143|154,154|156,156|168,168|172,181|202,202|205,206|212,213|216,217|222,222|231,233|236,237|242,242|256,258|270,270|274,276|306,306|320,320|330,332|338,339|350,351|360,360|363,363|367,372|379,380|400,401|406,407|409,409|416,416|440,445|465,465|470,476|485,486|510,513|516,517|524,524|531,531|536,536|538,538|553,553|564,564|570,570|583,584|587,587|591,592|594,599|601,601|605,605|609,611|622,622|624,626|633,634|638,641|643,645|647,648|663,663|665,675|679,679|696,700|717,717|747,747|751,751|758,758|762,762|769,769|772,772|778,778 Q:1,5|8,9|11,22|24,27|37,41|44,49|51,54|56,61|63,66|68,72|76,77|79,83|85,92|94,99|102,103|105,108|110,116|119,120|122,127|129,138|141,142|144,153|155,155|157,167|169,171|182,201|203,204|207,211|214,215|218,221|223,230|234,235|238,241|243,255|259,269|271,273|277,305|307,319|321,329|333,337|340,349|352,359|361,362|364,366|373,378|381,399|402,405|408,408|410,415|417,439|446,464|466,469|477,484|487,509|514,515|518,523|525,530|532,535|537,537|539,552|554,563|565,569|571,582|585,586|588,590|593,593|600,600|602,604|606,608|612,621|623,623|627,632|635,637|642,642|646,646|649,662|664,664|676,678|680,695|701,716|718,746|748,750|752,757|759,761|763,768|770,771|773,777 ?SEEEE??SS?HHHHHHHHHHHT?SEEE?????????TTGGG??EEEEEE?TTSS?HHHHTT?GGGS?EEEEE???EE?SSSEE-EEESSTTS?TTTEEE??SS?HHHH?EEEETTT??EE?GGGEEE?SSSSEEEEES??TT?EEEEEEEEEE?S?HHHHHHHHHHT?TTS????---???TTSHHHHHHHHHHHHHHHHT?TT??EEEES??SB??SEEE?TTSSEEEE--?TT??GGGB?HHHHHHHHHHHSS???THHHHGGGTTT?TTS???HHHHHHHHHHHHHHHHHHHHHHHHHHHTT?EEEEESSSSBTTT?TTSTTGGGG???EEEEE??SHHHHHHHHT??SSSEEEEE?SS?BST------TTSSTT??HHHHHHHHHHHHHHHHTTS??SEEE??B?HHHHHT?HHHHHHHHHHHHHHHHHHHHHTT????-?SSEEEEEESSGGGGTTTTT?SSTT???----TTTHHHHH--HHHHHHTSSSEEEEEEHHHHHHH-???TT??EEEEEE?TTSTTT?GGGG-G?HHHHHHHHHHHHHT?EEEEEESTTB?SSSST?SBTTHHHHTEEE??SS?TTB??B??????S?TTT-TTS???HHHHHHHHHS?B???BTTTBB??BSS????S???S??TTEEESSTTSEEEE?G-----------GGS?SEEEEEETTEEEEEES?????HHHHHHHHHHHHHHTT?STTSSTTEESSTTEEEEEEGGGTEEEEEE?SSS?EEEEEE?TTS?EEEEEE?TT?EEEEE? 2ZUV|A PF09510.5_Rtt102p_seed 6 164 !Q:6,21|28,29|31,67|69,69|71,72|79,80|83,99|105,163 Q:0,5|22,27|30,30|68,68|70,70|73,78|81,82|100,104 HHHHHS?????????????--?EEEEEE??B-----------????????-----?????????????B?S??EEEEEE??TT??--????????-????TTSSB????????????????????????????????????????????????-------???? 4I6M|D PF09511.5_RNA_lig_T4_1_seed 48 479 !Q:5,5|9,27|32,32|40,46|50,58|66,67|71,79|87,88|90,91|95,95|100,108|112,115|126,240|255,259|265,274|280,283|297,299|302,302|305,305|307,307|311,312|315,315|320,320|329,335|337,339|346,346|349,349|352,353|357,358|362,362|364,382|393,409|412,416|419,419|426,465|467,467|473,473 Q:0,4|6,8|28,31|33,39|47,49|59,65|68,70|80,86|89,89|92,94|96,99|109,111|116,125|241,254|260,264|275,279|284,296|300,301|303,304|306,306|308,310|313,314|316,319|321,328|336,336|340,345|347,348|350,351|354,356|359,361|363,363|383,392|410,411|417,418|420,425|466,466|468,472|474,478 GGTTT?EEE-------------------EETT-EEEEEEE???????BTT---------SSGGGSS??GGG---------EEEEEEE??S--EEE-EEEE---------ETT----EEEEEETTBS-------------------------------------------------------------------------------------------------------------------SSHHHHHHHHHHHS-----GGGHH----------HHHHH----HHHHHTTEEEEEE---EE?TT-S?SSS??SS?EEEE-EEEEETTT-----??B-??HHHHHH?TT-TG--GGB??EEE?S-------------------STHHHHHHHH?----------------SS---??EE-EEEETT----------------------------------------S?EEEEE?HHHHH 2C5U|A PF09515.5_Thia_YuaJ_seed 43 222 !Q:17,20|24,24|29,30|32,32|45,45|63,65|68,75|77,80|104,136|140,141|168,168|172,173|176,183|196,196|215,215|217,217 Q:0,16|21,23|25,28|31,31|33,44|46,62|66,67|76,76|81,103|137,139|142,167|169,171|174,175|184,195|197,214|216,216|218,221 HHHHHHHHHHHHHHTTS--??EEE-TTEE??G-GGHHHHHHHHHH?HHHHHHHHHHHHHHHHH---TT-------?S?--?SSHHHHHHHHTHHHHHGGGGGGG------------------------------???SSS??HHHHHHHHHHHHHHHHHHHHHHHHHH?GGG??TT?------?HHHHHHHHHHHH-HHHHHHHHHHHHHHHHHH?G-GGGS 3RLB|A PF09517.5_RE_Eco29kI_seed 6 193 !Q:2,6|14,14|16,17|25,25|32,35|42,43|48,48|51,51|54,54|57,59|76,76|79,80|91,92|111,112|119,120|123,127|130,132|134,141|148,150|156,157|159,178|192,192 Q:0,1|7,13|15,15|18,24|26,31|36,41|44,47|49,50|52,53|55,56|60,75|77,78|81,90|93,110|113,118|121,122|128,129|133,133|142,147|151,155|158,158|179,191 SS?????EEEEEEE?S??GGGTTHH-HHTSSS????SEEEEE??TTTS?SS?SS?SS???SHHHHHHHHHHHHHHT?SS??GGGEEEEEEE??SGGGGGHHHHHHHHHHHH??HHHHTS??TT?????SS???S-----???HHHHHS???GGGGG??S----------------????HHHHHHHHHHHHH? 3MX1|A PF09518.5_RE_HindIII_seed 5 338 !Q:2,38|54,54|69,69|73,73|104,109|111,111|122,122|129,130|135,141|146,147|157,160|170,170|175,175|179,179|181,182|207,217|219,221|226,227|241,244|251,252|266,267|303,304|317,317 Q:0,1|39,53|55,68|70,72|74,103|110,110|112,121|123,128|131,134|142,145|148,156|161,169|171,174|176,178|180,180|183,206|218,218|222,225|228,240|245,250|253,265|268,302|305,316|318,337 TS?------------------------------------HHHHHHHHHHHHHHS?HHHHHHHHHHHTEE?TTS?TTSHHHHHHHHHHHHHHHHHHHHTTEEEEE??????S?SEEEEESSSS?EEEEEE??EETT??--???GGGG-?HHHHHHHTT----TSSEEEEEE?GGGS?SSB?H--HHHHHHHHTEEEEEHHHHHHHHHT-----------T???BTTB??HHHHTHHHHHHTT--??GGGTTB??HHHHHHHHHHHHT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??HHHHHHHHHHHS?HHHHHHHHHHHHHHHHSGGG 3A4K|A PF09522.5_RE_R_Pab1_seed 5 134 !Q:1,4|9,14|33,34|42,42|45,45|47,47|53,54|56,56|63,64|78,81|85,87|90,93|100,100|115,115|130,133 Q:0,0|5,8|15,32|35,41|43,44|46,46|48,52|55,55|57,62|65,77|82,84|88,89|94,99|101,114|116,129 T????HHHH?----?EEEEEEEEETTEEEEEEE--EEEEEEE?TT-S?EEEEE??B?TTSSSB??EEEEEEEGGGSBS?--?TTS???TT?---EEEEEE?HHHHHHHHHHHHTT?HHHHHHHHHHHHHT???? 2DVY|A PF09532.5_FDF_seed 18 149 !Q:0,74|76,77|79,85|89,89|92,93|97,99|102,130|140,141|146,147 Q:75,75|78,78|86,88|90,91|94,96|100,101|131,139|142,145|148,148 -----????????????????????????????????????--------------????????????????????B??B???????EEE?TT??EEE???HH-----------------------------HHHHHHHHH--HHTT??H 3D3J|A PF09537.5_DUF2383_seed 79 121 !Q:5,6|28,33|63,94|96,96|119,119 Q:0,4|7,27|34,62|95,95|97,118|120,120 HHHHH--HHHHHHHHHHHHHHHHHHHHT??--?-HHHHHHHHHHHHHHHHHHHHHHHHHHHTT--??????-???????????????????????H-HHHHHHHHHHHHHHHHHHHHHH-S 4ETR|A PF09585.5_Lin0512_fam_seed 22 119 !Q:16,16|32,34|40,40|44,44|62,63|66,67|76,76|80,80|88,88|93,93|95,98|103,104 Q:0,15|17,31|35,39|41,43|45,61|64,65|68,75|77,79|81,87|89,92|94,94|99,102|105,118 EEEEEEEEEEEESSSS?HHHHHHHHHHHHHTT???SSHHH-HHT?SSGGGSEEEEEEEESSG--GG??HHHHHTTS?SSE-EEEEEEE?BEEE-E????GGGT??SSEEEEEEEEEEEE 3C8L|A PF09587.5_PGA_cap_seed 181 560 !Q:5,7|9,9|11,15|17,17|19,20|28,28|30,30|32,64|70,70|75,75|77,79|84,84|86,87|89,96|100,140|143,143|145,149|153,153|156,159|170,170|178,181|183,185|188,192|198,201|203,203|206,208|213,215|219,219|221,221|223,225|227,227|229,230|238,239|244,244|252,259|271,271|280,280|284,284|290,291|294,378|385,391|397,398|401,413|422,424|426,429|431,457|463,474|479,482|484,488|490,492|500,501|504,504|506,507|510,519|523,545|548,555|557,559 Q:0,4|8,8|10,10|16,16|18,18|21,27|29,29|31,31|65,69|71,74|76,76|80,83|85,85|88,88|97,99|141,142|144,144|150,152|154,155|160,169|171,177|182,182|186,187|193,197|202,202|204,205|209,212|216,218|220,220|222,222|226,226|228,228|231,237|240,243|245,251|260,270|272,279|281,283|285,289|292,293|379,384|392,396|399,400|414,421|425,425|430,430|458,462|475,478|483,483|489,489|493,499|502,503|505,505|508,509|520,522|546,547|556,556 EEEEE???T-T?---?S?B??TTSGGGT-S?B?-------------------------------?HHHHH-HHHH-H---HHHH?S--S--------EEE-----------------------------------------EE?S?---?SSS-SH----HHHTTTTHHH-HHHHTTS??--S---EE??-?-GGGGT----T?HH---HHHH---HHT-T?S---S?B??SEEETTS??BSSS?SEEEEEE--------TTEEEEEEEEE?HHHHHHHS?GGG?TTEEE??HH-------------------------------------------------------------------------------------HHHHHH-------HHHHT--TT------------?SEEEEEEE?--S----S?--------????--??????????-?HHHHH------------HHHH?---S-----S-??EEEEESS??SS?E--EE----------TTE-----------------------EE--------E??? 3IVE|A PF09588.5_YqaJ_seed 97 416 !Q:8,16|18,18|28,88|91,91|107,135|140,143|161,173|176,185|188,193|202,203|208,320|322,335|344,350|352,353|365,384|391,395|403,410|412,412|414,414 Q:0,7|17,17|19,27|89,90|92,106|136,139|144,160|174,175|186,187|194,201|204,207|321,321|336,343|351,351|354,364|385,390|396,402|411,411|413,413|415,415 HHHHHHTT?--------E-EGGGHHHHH-----------------------------------------------???-??-???----HH-HHHHHHHHHHHHHHS??---???------------------???HHHH----HHHHHHHHHHHHHHHHH??----------?EE?-----?-??EE?-----SSSTTEEE??SEEE-----------------------------------------------------------------------------------------------------------------T--------------TTEEEEEE???----H--HHHHHHHHHSS?------------------?HHHHHH-----HHHHHHH--------H-T?S 3POV|A PF09596.5_MamL-1_seed 6 61 !Q:0,3|57,60 Q:4,56 ??-?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT???? 3V79|M PF09598.5_Stm1_N_seed 24 100 !Q:0,66|69,70|73,81|83,84|86,86|88,91|93,93 Q:67,68|71,72|82,82|85,85|87,87|92,92|94,99 ??????????------------?-??????-???-??????????????------------??---?TT??SS---------S??S?S????S-HHHHHH 3U5G|h PF09607.5_BrkDBD_seed 3 60 !Q:0,6|12,13|22,22|28,28|39,39|59,59 Q:7,11|14,21|23,27|29,38|40,58 ???????HHHHH--HHHHHHHH?TTTTT?HHHHHHHTTS?HHHHHHHHTTHHHHHHHHT? 2GLO|A PF09618.5_Cas_Csy4_seed 32 231 !Q:6,8|12,12|31,34|36,37|39,40|44,44|47,47|52,60|63,64|72,73|85,85|92,93|98,100|103,105|108,110|113,113|117,129|139,167|169,169|175,175|178,184|186,188|196,196|198,200|204,205|207,208|210,210|214,214|218,226|229,230 Q:0,5|9,11|13,30|35,35|38,38|41,43|45,46|48,51|61,62|65,71|74,84|86,91|94,97|101,102|106,107|111,112|114,116|130,138|168,168|170,174|176,177|185,185|189,195|197,197|201,203|206,206|209,209|211,213|215,217|227,228 EEEEEE???TTS?HHHHHHHHHHHHHHHHHH----H??S??EEE?TT?BTTT---------TB??SEEEEEE-?HHHHHHHHHSS?STTTGG--GEEE???EE?-?SS??-EE?EEE?????------??HHHHHHHHH??----????????????????-???--?S?EEEEE?TT-------T??-EEEEEEE-E???BSS??S??B?TTS?BSS-------??EE?? 2XLJ|A PF09619.5_YscW_seed 11 114 !Q:0,6|18,21|24,25|33,36|58,58|73,75|87,88|90,91|99,99|101,103|111,111 Q:7,17|22,23|26,32|37,57|59,72|76,86|89,89|92,98|100,100|104,110|112,113 ?-?????EEEEEEEEESS?--?TT??EEEEEEE----EEEETTEEEEEEEEEEEESSS?EEEEEEEEHHHHTT??-EEEEEEEEETT??S??EEEEEEE?T---TSEEEEE?EE 2YJL|A PF09625.5_VP9_seed 6 86 !Q:5,5|12,14|23,23|30,34|39,39|42,42|51,51|54,55|61,61|71,71|74,74|79,85 Q:0,4|6,11|15,22|24,29|35,38|40,41|43,50|52,53|56,60|62,70|72,73|75,78 EEESS?EEEESS?-?TTHHHHHH-TSTTEE-----EEEE?SS?TTEEEEEE?TT??EEESS?HHHHHHHHT?TT?EEEE??????? 2GJI|A PF09626.5_DHC_seed 35 129 !Q:9,12|17,17|27,27|35,40|61,67|73,74|77,79|81,82|94,94|98,99|105,107|114,114|119,119|122,122|127,128 Q:0,8|13,16|18,26|28,34|41,60|68,72|75,76|80,80|83,93|95,97|100,104|108,113|115,118|120,121|123,126 HHHHTTSSS????GGGS?HHHHHHHHT?GGGBTTB???-??HHHHHHHHHHHHHTSTTTTS?-----?GGGTT??TT???S-?GGGSHHHHHHH-TTT??HHHHH---HHSSTT?GGGT?TT-GGGT?? 3U99|A PF09627.5_PrgU_seed 2 122 !Q:0,1|27,27|41,41|48,49|65,65|69,69|73,80|87,87|89,90|100,121 Q:2,26|28,40|42,47|50,64|66,68|70,72|81,86|88,88|91,99 ??EEEEEGGGEEEEEGGGTSBEEEEEE?HHHHHHHHHHTSS?TTTGGG??EEEEEETTEEEEEEB?GGG?EEE????????EEEEEB?S??BHHHHHHHH--------------???--??? 2GMQ|A PF09628.5_YvfG_seed 2 68 !Q:0,0|3,3|18,18|21,21|23,23|42,42|46,46|67,67 Q:1,2|4,17|19,20|22,22|24,41|43,45|47,66 ?TT?HHHHHHHHHHHHHH?SS-S?HHHHHHHHHHHHHHHHHH?SSS?HHHHHHHHHHHHHHHHHHHH? 2GSV|A PF09629.5_YorP_seed 2 71 !Q:0,1|4,5|7,7|10,10|15,15|18,18|25,26|36,38|41,41|51,51|56,56|63,67|70,70 Q:2,3|6,6|8,9|11,14|16,17|19,24|27,35|39,40|42,50|52,55|57,62|68,69 ??SS??S?TT?EEEE?TT?TTTSTT??SSEEEEEEE???SS?SEEEEETTS?EEEE?GGGEEE?????SS? 2HEQ|A PF09630.5_DUF2024_seed 13 83 !Q:0,0|10,11|15,16|24,25|27,29|46,48|50,52|57,59|64,65|81,82 Q:1,9|12,14|17,23|26,26|30,45|49,49|53,56|60,63|66,80 ?EEEEEEEEE??SSS??EEEEEEE--S???HHHHHHHHHHHHHHHT???S???TTTB???EEEE??HHHHHHHHHHSEEEE?? 2HFQ|A PF09631.5_Sen15_seed 44 196 !Q:10,11|17,18|24,24|27,49|61,98|106,109|111,111|126,130|136,136|139,158|166,166|170,170|176,183|186,196 Q:0,9|12,16|19,23|25,26|50,60|99,105|110,110|112,125|131,135|137,138|159,165|167,169|171,175|184,185 HHHHHHHHTT??SEEEE--EEETT-TT-----------------------EEEEEEESSTT???----------------------------------?EEEEEET----T?EEEHHHHHHHHHHH-----HHHTT?SS?-----------------??EEEEEEE?TTS?EEEEE--------EE---------?- 2GW6|A PF09632.5_Rac1_seed 2 297 !Q:0,5|27,29|51,51|54,54|78,97|117,119|150,151|211,222|264,264|266,266|268,268|296,297 Q:6,26|30,50|52,53|55,77|98,116|120,149|152,210|223,263|265,265|267,267|269,295 ??????HHHHHHHHHHHHHHHHHHHTT???HHHHHHHHHHHHHHHHHHHTS?SS?HHHHHHHHHHHHHHHHHHHHHHT????????????????????HHHHHHHHHHHHHHTTTTS???TTSHHHHHHHHHHHHHHHHHHHHHHTTSSS??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHTS????????????HHHHHHHHHHHHHHHHHTTTTHHHHHHHHHHHHHHHHHHTT?S?S?HHHHHHHHHHHHHHHHHHHHHHHHHHH?- 2H7V|C PF09633.5_DUF2023_seed 10 103 !Q:14,14|38,39|44,45|57,57|72,72|76,77|90,91 Q:0,13|15,37|40,43|46,56|58,71|73,75|78,89|92,102 HHHHHHHHHHHHTS?SEEEEEEEGGGHHHHHHHHHHTT??EEEE??TTSSEEEEEEE?HHHHHHHHHHHTTS?GGG??HHHHHHHHHHTT??HHHHHHHHHHH 2GUK|A PF09634.5_DUF2025_seed 5 106 !Q:0,4|14,16|32,32|36,36|41,41|45,45|64,64|76,76|82,83|92,93|98,98|102,105 Q:5,13|17,31|33,35|37,40|42,44|46,63|65,75|77,81|84,91|94,97|99,101 ?????GGGGGGGGS???EEEEETTTTEEEEES?GGG?SSSS?GGG?EEHHHHTEEESSSSEEEE?TTHHHHHHHHT?HHHHT??HHHHHHTT??SSSS?EEE???? 2HG6|A PF09635.5_MetRS-N_seed 5 125 !Q:2,3|21,22|26,27|30,30|33,34|36,37|41,41|43,44|46,49|60,61|83,84|87,88|104,105|107,109|112,113 Q:0,1|4,20|23,25|28,29|31,32|35,35|38,40|42,42|45,45|50,59|62,82|85,86|89,103|106,106|110,111|114,124 SS??HHHHHHHHHHHHHHHHH??STT??EE?SS??S??EEE?S??S????HHHHHHHHTT??TTTTSHHHHHHHHHTTTGGGS--SS??HHHHHHHHHHHHHHT?-S???SS??HHHHHHHHHHH 2HSN|A PF09636.5_XkdW_seed 4 108 !Q:0,1|10,10|13,14|24,24|27,29|36,36|40,43|58,107 Q:2,9|11,12|15,23|25,26|30,35|37,39|44,57 ??HHHHHHHH?TT??BTTTEEEEE?SS?--EEEEEE?SSS????HHHHHHHHHHHHHS?????????????????????????????????????????????????? 2HG7|A PF09637.5_Med18_seed 26 428 !Q:27,31|43,45|47,47|51,59|61,62|64,64|67,67|70,72|74,74|80,82|91,92|95,95|100,177|184,189|191,191|193,193|208,296|302,302|313,313|329,329|333,333|343,345|351,371|387,391|393,393|415,416|418,420|425,426 Q:0,26|32,42|46,46|48,50|60,60|63,63|65,66|68,69|73,73|75,79|83,90|93,94|96,99|178,183|190,190|192,192|194,207|297,301|303,312|314,328|330,332|334,342|346,350|372,386|392,392|394,414|417,417|421,424|427,427 EEEEEEEEEEGGGHHHHHHHHHHHHSS-?--?EEEEEEEEEEE---E?TTS------???S--B?TT?BB???B?EEEEE???GGGHHHHT--TT?SSTT?????????????????????????????????????????????????????????-????????????????????EEEEEE??????S-S?SSEEEEEEEEEEEE-----------------------------------------------------------------------------------------EEESS?SHHHHHHHTT-EEEEEEEEEEEEEEE?GGG?EEEEEEEEE-??TTEEE---------------------ETTTTEEEEEEEEEE?????H-HHHHHHHHHHHHHHHHHTTTS??B???GGGG??B 4GWQ|E PF09638.5_Ph1570_seed 4 156 !Q:28,29|46,46|49,50|62,65|69,76|79,79|81,83|98,99|102,108|125,125|131,131|155,155 Q:0,27|30,45|47,48|51,61|66,68|77,78|80,80|84,97|100,101|109,124|126,130|132,154 EEEETTEEEETTEEEETTTTEEEEEEES??HHHHHHHHHHHHHHHH?SS??HHHHHHHHHHT????GGG????????EE?S???HHHHHHHHHHHHHH??SS???----GGGSEEEEETTEEEEE?SSEEE?TTSEEEEESSTTHHHHHHTTTTT? 2HQ4|A PF09639.5_YjcQ_seed 8 103 !Q:11,11|13,15|22,22|24,31|49,50|56,59|63,64|67,68|71,71|73,75|86,86|88,102 Q:0,10|12,12|16,21|23,23|32,48|51,55|60,62|65,66|69,70|72,72|76,85|87,87 HHHHHHHHHHH?S???HHHHTS?H--------HHHHHHHHHHHHHTSEE??EESSS----SEE??SS??EE?H---HHHHHHHHHT?S??????????????? 2HGC|A PF09640.5_DUF2027_seed 5 163 !Q:0,1|10,10|13,13|17,18|26,26|52,52|63,63|70,70|81,81|85,91|97,99|105,105|131,131|135,162 Q:2,9|11,12|14,16|19,25|27,51|53,62|64,69|71,80|82,84|92,96|100,104|106,130|132,134 ??EEEEEEES?TT?TTT??EEEEEEE?SSSEEEEEEEEEETTEEEEEEEEEE?TTEEEEEEEE?GGGGGG?SSEEEEEEEE?SSS???????EEEEE???GGGGG?GGGSEEETTEEEEEEEEEEEETTEE?TTS??-------------------------- 2HUH|A PF09641.5_DUF2026_seed 4 208 !Q:0,0|18,18|20,22|43,45|59,61|70,75|77,78|83,83|105,105|108,111|113,117|126,127|132,134|138,138|144,144|158,158|172,174|178,180|187,187|191,191|197,205|207,207 Q:1,17|19,19|23,42|46,58|62,69|76,76|79,82|84,104|106,107|112,112|118,125|128,131|135,137|139,143|145,157|159,171|175,177|181,186|188,190|192,196|206,206 ?HHHHHHHHHHHHHHHGG-G???HHHHHHHHHHHHHHHHHHHH???EEEEEEEEEEEET---TEEEEESB??????B??SSTT?EEEEEETTEEEETTGGGTTTT?GG----G?????BEEEEGGG??SSTT???STT?EEEEE?HHHHHHHTTTGGG?HHHHHHHHHHHHH???TTS???SEEEEE?TTS?EEEEE?????-???B? 2HLY|A PF09642.5_YonK_seed 2 62 !Q:0,1|9,10|24,24|27,27|44,57|59,61 Q:2,8|11,23|25,26|28,43|58,58 ??EEEEEEE??SEEETTTTEEEEE?SS?EEEEEHHHHHHTTTTS??????????????S??? 2H4O|A PF09643.5_YopX_seed 63 216 !Q:0,0|20,22|26,26|33,33|48,48|56,56|59,60|63,72|74,76|82,83|86,86|90,90|97,101|106,114|117,134|139,142|154,184|186,187|197,197|199,200|208,208|214,215 Q:1,19|23,25|27,32|34,47|49,55|57,58|61,62|73,73|77,81|84,85|87,89|91,96|102,105|115,116|135,138|143,153|185,185|188,196|198,198|201,207|209,213 ?EEEEETTTTEEEEEEEEEE?--TTS?EEEEES?EEEEEETTEEEEEE?SEEEGGG?SS??EE----------E---EEEEE--EE?TTS?EEETTE-----EEEE----?????TT--------------????EEEE----EEETTEEEETT?-----------------------------?S??SHHHHHSTT?E--EEEEETT-TSTTS?? 2OX7|A PF09644.5_Mg296_seed 3 125 !Q:0,0|18,18|36,36|38,38|44,46|48,48|68,84|90,92|112,113 Q:1,17|19,35|37,37|39,43|47,47|49,67|85,89|93,111|114,124 ?HHHHHHHHHHHHHHHTS?HHHHHHHHHHHHHHHTS?S?TTTSS???S?HHHHHHHHHHHHHHHHHHH???-?????????????HHHHH---HHHHHHHHHHHHHHHHHTT??TTHHHHHHHHH 2I15|A PF09645.5_F-112_seed 2 110 !Q:0,3|22,22|31,33|51,51|60,60|63,63|69,109 Q:4,21|23,30|34,50|52,59|61,62|64,68 ????HHHHHHHHHHHHHHHSEE?HHHHHHHH???HHHHHHHHHHHHHHHHH?TTTEEEEE?SS?EEEEE????????????????????????????????????????? 2VQC|A PF09646.5_Gp37_seed 13 151 !Q:8,8|15,16|19,19|23,26|42,45|47,47|50,50|70,72|87,89|92,92|95,96|106,108|112,112|127,150 Q:0,7|9,14|17,18|20,22|27,41|46,46|48,49|51,69|73,86|90,91|93,94|97,105|109,111|113,126 HHHHHHHH?TTEEEE??SS?TTT????SSSEEEEEEEEEEEE????S?SS?EEEEEEEEEEEEEESSHHH---HHHHHHHHHHHHTT???TT?SS??EEEEEEEEE--?GGG?EEEEEEEEEEEEEE???????????????----????? 2GJV|A PF09648.5_YycI_seed 33 325 !Q:0,1|11,13|22,22|24,25|27,30|32,37|48,53|60,64|71,71|73,76|79,83|96,117|131,141|148,152|163,166|183,185|188,188|193,193|195,198|206,206|210,212|221,221|229,233|236,236|240,241|252,253|256,256|258,258|261,261|263,265|275,282|294,294|306,313|323,323 Q:2,10|14,21|23,23|26,26|31,31|38,47|54,59|65,70|72,72|77,78|84,95|118,130|142,147|153,162|167,182|186,187|189,192|194,194|199,205|207,209|213,220|222,228|234,235|237,239|242,251|254,255|257,257|259,260|262,262|266,274|283,293|295,305|314,322|324,324 ??HHHHHHHHH---HHHHHHTT?B??S-???S?-----EEEEEEEEEE????--HHHHTT-----STTEEE?S????SS--???SEEEEEEEEEEE??--------------------SSSHHHHHHHHHH-----------HHSTTG-----GGEEEEEEET----TTTEEEEEEEETTEEE???SS-SGGG?S----SEEEEEE?SSS---EEEEEEEE?EEEEEEE-----EE-EEE??HHHHHHHHHH--TT?S?TT?E---EEEEEEEEE--------EEEEETTEEEE-EEEEEEEEEEE????????EEEEEEEEE?B 2O3O|A PF09649.5_CHZ_seed 25 38 !Q:5,5|7,10|15,17|20,26 Q:0,4|6,6|11,14|18,19|27,37 GGGGS?S????GGGT???SS???????TTTHHHHHHHH 2JSS|B PF09651.5_Cas_APE2256_seed 28 171 !Q:3,3|18,19|24,26|52,63|66,66|68,68|74,80|82,85|90,91|95,100|116,116|122,122|124,124|129,129|133,133|147,147|150,151|159,159|168,170 Q:0,2|4,17|20,23|27,51|64,65|67,67|69,73|81,81|86,89|92,94|101,115|117,121|123,123|125,128|130,132|134,146|148,149|152,158|160,167 GGG?HHHHHHHHHHHHHT??GGGE---EEEEEEESSHHHHHHHHHHHHHHHH------------TT?E-EEEEE-------E????SHHH--HHH------HHHHHHHHTHHHHHH-HHHTT?E-EEEE?SSS?HHHHHHHHHHHHH-TT??EEEEEET-TTTEEEEE??? 3QYF|A PF09663.5_Amido_AtzD_TrzD_seed 10 371 !Q:7,7|12,13|26,26|40,40|45,46|65,66|81,83|86,88|98,100|102,104|106,107|109,109|118,122|148,149|162,165|177,179|181,181|183,183|207,207|211,212|219,219|222,223|232,232|235,235|238,238|249,251|265,265|278,279|282,290|304,306|316,317|321,321|325,325|346,346|352,353|361,361|370,370 Q:0,6|8,11|14,25|27,39|41,44|47,64|67,80|84,85|89,97|101,101|105,105|108,108|110,117|123,147|150,161|166,176|180,180|182,182|184,206|208,210|213,218|220,221|224,231|233,234|236,237|239,248|252,264|266,277|280,281|291,303|307,315|318,320|322,324|326,345|347,351|354,360|362,369 EEEEEEE?SSTT??HHHHHHHHTTSS?GGGEEEEEEEESS?SSTT??HHHHHHHHHHHHHHHHHT??HHHHHHHSEEEEEE???TT???EEEEEEEEE???S???S--S?EEEEEEEE?????GGGTTSHHHHHHHHHHHHHHHHHHT??SGGGEEEEEEEE????HHHHHHHHHTT???S?S?HHHHHHHHHHHHHHHHHHHTTSS?GGG??GGGTTT?TT??BSSEEEEE?TT?SS?EEEEEEEETT???SEEEEEEEESSTT?HHHHHHHHHTTT??SG---------GGGGGEEEEEEEE???TTSEETTEE??TTS?SSS?HHHHHHHHHHHHHHHHHSSS?SEEEE??TTBSSTT?EEEEEEEE? 3ZGU|A PF09668.5_Asp_protease_seed 12 127 !Q:0,24|40,40|43,43|46,46|58,58|67,67|70,77|93,93|105,105|107,107|114,114|123,123 Q:25,39|41,42|44,45|47,57|59,66|68,69|78,92|94,104|106,106|108,113|115,122|124,126 ?????????????????????????EEEEEETTEEEEEEE?TT?SS?EEEHHHHHHTT?GGGEEGGG?EE????-???EEEEEEEEEEEEETT-EEEEEEEEEET-T?SSSEEE?HHHHHHTT?EEE 3S8I|A PF09683.5_Lactococcin_972_seed 6 68 !Q:0,3|10,12|26,26|45,45|56,57|61,62 Q:4,9|13,25|27,44|46,55|58,60|63,67 ---?EEEEEE?--SSEEEEEEEESSS?EEEEEEEETTTEEEEEEE?SSEEEEEEEE?-SSS-?EEEEE 2LGN|A PF09691.5_PulS_OutS_seed 8 117 !Q:0,25|48,49|53,54|71,72|76,78|97,98|110,110 Q:26,47|50,52|55,70|73,75|79,96|99,109|111,116 ????????????????????----??HHHHHHHHHHHHHHHHHHHHHS??TTS??HHHHHHHHHHHHHHTT??TTS--?TTSHHHHHHHHHHHHHSS??HHHHHHHHHHH?HHHHHH 3UTK|A PF09699.5_Paired_CXXCH_1_seed 178 67 !Q:3,3|7,10|16,21|26,31|34,34|36,49|66,66 Q:0,2|4,6|11,15|22,25|32,33|35,35|50,65 GSS?TTG----GGGTS------SSTT???--?TT?S--------------HHHHHHHHHHHHHHHT? 2OZY|A PF09700.5_Cas_Cmr3_seed 33 601 !Q:0,0|8,35|48,67|69,89|94,94|101,111|119,123|129,137|145,147|151,177|183,210|212,212|221,221|226,227|232,240|245,302|304,326|334,334|337,338|346,360|365,370|373,378|381,394|397,399|404,407|415,416|421,421|425,425|429,455|466,467|475,476|478,478|480,483|486,488|492,492|498,500|502,508|511,516|518,518|521,521|523,537|548,549|554,554|556,580|582,587|592,593|600,600 Q:1,7|36,47|68,68|90,93|95,100|112,118|124,128|138,144|148,150|178,182|211,211|213,220|222,225|228,231|241,244|303,303|327,333|335,336|339,345|361,364|371,372|379,380|395,396|400,403|408,414|417,420|422,424|426,428|456,465|468,474|477,477|479,479|484,485|489,491|493,497|501,501|509,510|517,517|519,520|522,522|538,547|550,553|555,555|581,581|588,591|594,599 ?EEEEEEE??????????---?????---???????HHHHHHHHHHHH?????????---????????S---------------------SEEE-EEEEEE-----------TTEEEEE---??TTEEE---------ETTEEEE???EEE---------------------------TTEEE????------------------??????E-EEHHHHHH-HHTT??SEEE---------TTTS?--------------???????????????????----------?????????-????S-----------------------EEEEEEE?SS??HHHHHHS--------------?EEEE??????EE------EE??------------BS???GGGS????EEEEEEE--EESS?EES?HHH---------------------------HHHHHHHHTT??EEEEEEE??S?E----EE?-?EET-TTTEE???E-------EE------E?TT?E---------------EEEEEEEEEE??SEEE?S-------------------------B-----?TTBT??EEEEEE? 1G6R|B PF09701.5_Cas_Cmr5_seed 25 191 !Q:14,32|40,54|76,76|90,91|102,103|107,109|114,114|117,118|136,136|139,152|161,164|190,190 Q:0,13|33,39|55,75|77,89|92,101|104,106|110,113|115,116|119,135|137,138|153,160|165,189 SHHHHHHHHHHHHH-------------------HHHHHHT?--------------HHHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHTT??HHHHHHHHTT??SSS???GGGS?SS??HHHHHHHHHHHHHHHHT?TT-------------?STTGGGTS---?HHHHHHHHHHHHHHHHHHHHHHHHH? 4GKF|A PF09704.5_Cas_Cas5d_seed 102 419 !Q:0,0|8,8|12,14|16,16|19,20|25,28|30,30|33,34|46,85|98,98|100,102|107,116|118,124|133,152|155,155|166,167|173,173|179,191|204,204|207,208|211,234|250,251|254,255|264,264|269,270|272,304|308,308|313,335|343,348|350,386|388,389|393,393|396,400|406,408|417,418 Q:1,7|9,11|15,15|17,18|21,24|29,29|31,32|35,45|86,97|99,99|103,106|117,117|125,132|153,154|156,165|168,172|174,178|192,203|205,206|209,210|235,249|252,253|256,263|265,268|271,271|305,307|309,312|336,342|349,349|387,387|390,392|394,395|401,405|409,416 ?EEEEEEE-EEE??-B?SS??SSEE----B?SS??HHHHHHHHHHH?-------------------------------------??TTEEEEEEEEEE?S???EEEE??????????H-------HHHHHHHH--------------------TT?HHHHHHHHHH--HHTTT?EEEEE-------------EEEEEEEEEEEE?TT??TT?----------------------?HHHHHHHHHHHHHTT??SS??BSSSTTSB?EEEE??S-----------------???---????-----?TTT?SEEE-----------------------EEEEEEE------E------------------------------------?T--TTS?SE-----EEEEE---EEETTEEE?? 3VZI|A PF09707.5_Cas_Cas2CT1978_seed 33 93 !Q:8,9|31,31|33,34|49,53|56,57|65,65|68,68|71,71|78,92 Q:0,7|10,30|32,32|35,48|54,55|58,64|66,67|69,70|72,77 EEEEEEES??HHHHHHHHHHSEEEETTEEEE-E??HHHHHHHHHHHHHH----?TT-?EEEEEEE?SS-SS?EEEEEE??????????????? 4MAK|A PF09711.5_Cas_Csn2_seed 5 188 !Q:11,11|13,13|17,17|21,21|23,24|33,33|37,38|41,41|59,59|87,94|104,111|127,127|130,131|138,138|142,143|158,158|160,160|168,169|174,174|178,178|181,182 Q:0,10|12,12|14,16|18,20|22,22|25,32|34,36|39,40|42,58|60,86|95,103|112,126|128,129|132,137|139,141|144,157|159,159|161,167|170,173|175,177|179,180|183,187 HHHHHHHTTSS?S?EEE?STT?B??GGGEEEES?TTT??TT?HHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHHHHHHHHHHHSSS????????HHHHHHHHT????????SHHHHHHHHHHHHHH?TT??EEEEES?GGG??HHHHHHHHHHHHHH?S?EEEEESS??TTSS?EEE?TT??EEETT 3V7F|A PF09719.5_C_GCAxxG_C_C_seed 81 180 !Q:0,3|15,15|22,25|38,38|40,43|45,45|58,75|77,78|82,103|119,120|122,123|125,127|137,145|152,153|173,173 Q:4,14|16,21|26,37|39,39|44,44|46,57|76,76|79,81|104,118|121,121|124,124|128,136|146,151|154,172|174,179 ----HHHHHHHHHHH?TTGGGS---?GGGGGGGGGGTT-T-???B?HHHHHHHHHHHH------------------H??HHH----------------------HHHHHHHHHHHHHHS?-B??S--?SBHHHHHHH---------HHHHHT??TTSHHHHHHHHHHHHHHHH-HHHHHH 1H21|A PF09734.4_Tau95_seed 52 1166 !Q:0,259|262,262|264,388|390,684|687,764|766,767|770,1028|1030,1063|1079,1079|1089,1090|1094,1094|1097,1103|1110,1124|1135,1135|1148,1149|1153,1153|1160,1160|1164,1165 Q:260,261|263,263|389,389|685,686|765,765|768,769|1029,1029|1064,1078|1080,1088|1091,1093|1095,1096|1104,1109|1125,1134|1136,1147|1150,1152|1154,1159|1161,1163 --------???-------??--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?????-----?--------------------?-----?--EE?T-----------------------------------------------------------------------------------------------------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?SS-------???--------------------------------------------------------------------S??TT???--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------??H----------------------------------HHHHHHHHHHHHHHH?SEEEHHHHH--TTS?GG-------GTTTHH---------------HHGGGTEEEE?SSTTTTEEEETT??TTS?GGGGGG?EEE?? 4BJJ|A PF09735.4_Nckap1_seed 8 1269 !Q:4,4|37,37|42,42|58,66|111,114|142,142|163,164|168,168|212,213|224,224|230,230|236,239|248,248|270,270|284,284|294,322|337,337|347,368|405,405|438,444|447,449|454,455|502,502|504,506|517,520|527,528|536,542|561,561|564,564|568,568|571,579|596,596|606,607|613,613|629,629|649,650|653,653|690,691|706,706|715,734|740,741|743,743|747,748|767,767|769,769|778,778|801,802|809,811|835,836|850,861|865,866|870,870|872,872|906,906|910,913|915,915|972,972|975,975|981,982|988,1003|1036,1036|1049,1057|1072,1074|1077,1077|1086,1093|1097,1097|1119,1119|1123,1123|1134,1134|1149,1179|1184,1184|1187,1188|1210,1212|1216,1221|1239,1239|1242,1243|1252,1252|1265,1268 Q:0,3|5,36|38,41|43,57|67,110|115,141|143,162|165,167|169,211|214,223|225,229|231,235|240,247|249,269|271,283|285,293|323,336|338,346|369,404|406,437|445,446|450,453|456,501|503,503|507,516|521,526|529,535|543,560|562,563|565,567|569,570|580,595|597,605|608,612|614,628|630,648|651,652|654,689|692,705|707,714|735,739|742,742|744,746|749,766|768,768|770,777|779,800|803,808|812,834|837,849|862,864|867,869|871,871|873,905|907,909|914,914|916,971|973,974|976,980|983,987|1004,1035|1037,1048|1058,1071|1075,1076|1078,1085|1094,1096|1098,1118|1120,1122|1124,1133|1135,1148|1180,1183|1185,1186|1189,1209|1213,1215|1222,1238|1240,1241|1244,1251|1253,1264 GGGS?HHHHHHHHHHHHHHHHHHHHHHHHHHHSTTTS?GGGT?TTTHHHHHHHHHHTT?????????TTHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT????TTTSHHHHHHHHHHHHHHHHHHHHHHT?TTHHHHHHHHHHHHHTTSSS??TTH-HHHHHHHHHTSSHHHHHHHHTTTTHHHHHHHHHGGGGTHHHHS??HHHHHHTTTT?SSSSG-GGTTS????TTHHHHHS?HHHHHHHHHHHHHHTTHHHHH?HHHHHHHHHHHTT?SEEEEETTE-----------------------------EEEHHHHHHHHHTT?GGGTTHHHH----------------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?GGGGTTTHHHHHHHHHHHHHHHHHHHHHHHHS?-----?SS---TTTT??TTHHHHHHHHHHHHHHHHHSHHHHHHHHHHHHHHTHHHHHHHHHTT?S???HHHHHHHHHH----HHHHHT??HHHHHTT???--??HHHHHHHHHHHHHHHSTT?SS?GGG?HH---------HHHHHHHHHHHHHHHH?HHHHHHHHH??GGGGG?HHHHHHHHHHHHHSH-HHHTTTTHHHHHGGGGGGG??TT?GGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--HHHHHHTTSGGGGH-HHHHHHTT?????--??????-??????TTGGG??S?TTS??HHHHHHHHHHHHHHHHTS?S?EEETTEEE?HHHHHHHHHHHHHHHHHHHHTT?-BTTTTB???HHHHHHHHHHHHHHHHHGGGTSS??HHHHHHHHHHHTT------------SSB?-TTS?B?HHHHHHHHHHHTHHHHHHTTSEEEETTTTEEEE?SSS????S?THHHHSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTHHHHHHHHH?TT?HHHHH--HHHTT??-------------?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHH???-?????SSHHHHHHHHHHTT???SS?HHHHHHHT????????HHH-HHHHHHHHHHHHHHHGGGGGG?GGG?EETTTTEETT?GGGHHHHHHHHHHH-------------------------------HHHH-TT??HHHHHHHHHHHHHHHHHHTTS???TTT------TTTHHHHHHHHHHHHHH?TT??HHHHHHHS?HHHHHHHHHHHH???? 3P8C|B PF09738.4_DUF2051_seed 7 382 !Q:0,152|230,381 Q:153,229 -----------------------------------------------------------------------------------------------------------------------?-------------------------????????THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTS???-------?-------------------------------------------------???------------------------------------------------------------------------------???-??????? 4H22|A PF09749.4_HVSL_seed 27 345 !Q:0,45|51,54|57,58|62,64|67,68|80,80|85,85|88,88|91,117|124,124|126,127|133,133|148,151|155,157|160,160|164,164|167,168|172,172|185,185|187,194|199,202|219,265|268,270|279,279|281,282|288,290|304,304|312,325|328,329|344,345 Q:46,50|55,56|59,61|65,66|69,79|81,84|86,87|89,90|118,123|125,125|128,132|134,147|152,154|158,159|161,163|165,166|169,171|173,184|186,186|195,198|203,218|266,267|271,278|280,280|283,287|291,303|305,311|326,327|330,343 ---------------------------------------???????EEEEE----EE--EEE???HH--HHHHHHHHHHH-HHTT?TT?EE?--------------------------SSEEEE?S??EEEEG-GGHHHHHHHHHHHH----TTS???EE?EEE-EE--EEE?TTSSEEEEEEEE?T--------THHH----HHHHHHHHHHHHHHTT?????------------------------------------------SS???EEEEEEEE-S??HHHHT---THHHHHHHHHHHT?SSTHHHH-------------?EE??EEEEEETTEEEEEE?- 4H7W|A PF09754.4_PAC2_seed 126 352 !Q:23,24|26,26|32,34|39,40|45,46|48,51|57,58|62,67|71,73|87,104|113,117|119,120|122,122|124,124|127,133|139,139|149,150|162,163|165,166|169,173|179,180|185,185|189,213|215,217|227,227|232,233|243,266|269,269|271,274|276,277|287,288|291,291|295,306|309,316|333,339|346,351 Q:0,22|25,25|27,31|35,38|41,44|47,47|52,56|59,61|68,70|74,86|105,112|118,118|121,121|123,123|125,126|134,138|140,148|151,161|164,164|167,168|174,178|181,184|186,188|214,214|218,226|228,231|234,242|267,268|270,270|275,275|278,286|289,290|292,294|307,308|317,332|340,345 EEESTTBTTSHHHHHHHHHHHHT--T?EEEEE?-?GGGT??TTTS??E----EEEET--TEE------EEE???EEEEEEEEESSSE------------------EEEEEEEE-----E??S-S?HH-------HHHHH-HHHHHHHHT??EEEEEEEEEES??T--TS?--??EEEEE??HHHH-HHS?------------???????-----S???HHHHHHHHH-HHHT??EEEEEEEEE------------------------GG-G??--S??HHHHHHHHH--HH-HHH------------HT???-?--?TTHHHHHHHHHHHHTT-??????HHHHTT??-??? 2WAM|A PF09756.4_DDRGK_seed 16 201 !Q:0,2|5,108|120,120|124,124|133,133|135,135|141,141|154,154|158,158|160,160|162,163|167,169|171,182|184,200 Q:3,4|109,119|121,123|125,132|134,134|136,140|142,153|155,157|159,159|161,161|164,166|170,170|183,183 ???SS--------------------------------------------------------------------------------??----------------------HHHHHHHHHHH?SEE?HHHHHHHH?S?HHHHH-HHHHHHHHHSSS?EEE?T-T??EEE???S------------S??--------------? 1WI9|A PF09764.4_Nt_Gln_amidase_seed 14 253 !Q:0,2|5,5|18,19|26,26|32,35|41,52|56,56|68,69|71,73|78,78|85,91|102,102|108,114|118,123|134,135|137,138|142,142|146,156|170,171|173,174|179,179|183,183|187,189|192,193|195,196|199,199|201,208|212,212|215,217|222,237|252,252 Q:3,4|6,17|20,25|27,31|36,40|53,55|57,67|70,70|74,77|79,84|92,101|103,107|115,117|124,133|136,136|139,141|143,145|157,169|172,172|175,178|180,182|184,186|190,191|194,194|197,198|200,200|209,211|213,214|218,221|238,251 ???TT?HHHHHHHHHHHH--HHSSSS?GGGEE----EEEEE-----------?TTS?EEESSBTTSTT--S??-EEES?EEEEEE-------EETTTEEEEE?TTBSS------?SSE------EHHHHHHHTT??S--TTS?GGG---------??EEEEEEHHHHHHH??B??GGGB?SSS?BSS???SS??B??SS?S------??THH-HH???TTSS----------------SSEEEEHHHHHHHH? 3C9Q|A PF09765.4_WD-3_seed 9 298 !Q:4,4|12,12|16,16|42,42|45,45|50,52|62,62|67,69|72,73|86,103|107,108|119,119|122,122|127,127|131,131|142,142|154,158|165,165|169,169|178,179|210,212|217,218|221,222|239,240|242,242|275,276|280,280|291,291|294,297 Q:0,3|5,11|13,15|17,41|43,44|46,49|53,61|63,66|70,71|74,85|104,106|109,118|120,121|123,126|128,130|132,141|143,153|159,164|166,168|170,177|180,209|213,216|219,220|223,238|241,241|243,274|277,279|281,290|292,293 HHHH?TTEEEEE?SSS?EEEEEEEEETTEEEEEEEEETTTTS?TT?EEEE---EETTEEEEE?TTTS???TT??HHHHHHHHHHHS???????????------?GGG??HHHHHHHHHS?SS?EEEE?GGG?EEEEEEETTE-EEEEEEEETTT---??EEEESS?TTS?HHHHHHHH??SHHHHHHHHHHHHHHTHHHHHHHHHHHHHS???BSSS??TT??EEEEEEETTEEEEEEE--S?TTSTTTTEEEEEESSHHHHHHHHHHHHHHHHT??TTS?HHHHHHHHHT?SS???? 3ZQS|A PF09770.4_PAT1_seed 17 1183 !Q:0,605|607,768|794,825|834,834|836,842|844,846|849,859|861,861|883,884|890,890|903,903|910,910|914,914|917,920|924,932|938,939|957,958|972,972|975,975|999,1000|1002,1023|1041,1041|1044,1044|1051,1052|1057,1058|1065,1072|1076,1096|1101,1102|1107,1110|1132,1162|1177,1182 Q:606,606|769,793|826,833|835,835|843,843|847,848|860,860|862,882|885,889|891,902|904,909|911,913|915,916|921,923|933,937|940,956|959,971|973,974|976,998|1001,1001|1024,1040|1042,1043|1045,1050|1053,1056|1059,1064|1073,1075|1097,1100|1103,1106|1111,1131|1163,1176 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------?---------------------------------------------------------------????-----------???----------------------------------------------?--------????--------------------------------------------------------------------------------------------------------------------------------------------??------------------------?---------------------------------?S------------------------------------------------------------------------?-----------------------------------------------------------------------------------------SHHHHHHHHHHHHHHHHHHHTTSSS??----------------------------??HHHHHTTT?S-------S???SS-----------S?HHHHHTTSHHHHHTHHHHHHT??TTTHH-HHHHHHHHTGGG?TTTTTT?TTT?SS--??HHH---------HHHHH--HHHHHHHHHHHHHHHHS??HHHHHHHHHHHHH-TS?TTTGGGSHHHHHHHHHHHHHHHT??S?----?-????-------????HHHHHHHHHHHHHHHHH-HH-HTTSSS??HHHH--HHHHHH????????HHH---------------------HHHH--HHHH????HHHHHHHHHHTHHHHHHHHHH???????????????????????????????HHHHHHHHHHHHHH?----- 2XES|A PF09795.4_Atg31_seed 5 210 !Q:0,5|12,12|15,48|50,50|53,55|60,60|63,84|86,87|94,95|98,101|110,110|113,133|138,138|142,165|172,178|182,183|187,187|209,209 Q:6,11|13,14|49,49|51,52|56,59|61,62|85,85|88,93|96,97|102,109|111,112|134,137|139,141|166,171|179,181|184,186|188,208 ???--?EEEEEE?SS????-???------???????--???-----???E-EE???EEEE?TT???-??????----------??S??EEEEEE??SS????EEEEEESS?EE???------------------EEET-TTE------------------------EEEEEE???-???TTT--TSS?HHHHHHHHHHHHHHHHHHHHT? 4HPQ|B PF09806.4_CDK2AP_seed 11 361 !Q:1,283|285,291|296,302|326,326|348,350|358,360 Q:0,0|284,284|292,295|303,325|327,347|351,357 S-------------------------------------------------------------------------------------------------------------------------------?--------------------------------------------------------------------------------------------------------------------------------------------------------???S?------SSSS------?HHHHHHHHHHHHHHTTHHHHHTT?HHHHHHHHHHHHHHHHHHHHH---HHHHTTS??? 2M1L|A PF09817.4_DUF2352_seed 9 717 !Q:0,0|13,13|16,18|24,26|28,35|41,68|70,128|130,130|132,132|148,148|150,150|153,154|157,158|160,166|172,174|178,178|189,192|209,211|215,219|233,233|235,236|248,262|271,273|275,279|282,285|295,310|327,333|335,335|338,338|340,341|353,353|355,716 Q:1,12|14,15|19,23|27,27|36,40|69,69|129,129|131,131|133,147|149,149|151,152|155,156|159,159|167,171|175,177|179,188|193,208|212,214|220,232|234,234|237,247|263,270|274,274|280,281|286,294|311,326|334,334|336,337|339,339|342,352|354,354 ?EESSSSEEEEEE?TT???GGGGT--?S?----???EEEEE----------------------------E???????????????????????--------????????-------------------?B?B?HHHHHHHHHHHHHHH?T-TS??SS??S???????EEEEB???STT?EEEEEEEEEE----ETTEEEEEEEEEEEEE---EES?????HHHHHHHHHHHHT?S??EEEEEEEEEEE???????????????EEEEEEES???S-----TT????TTSEEEEEE???????????-????HHHHHHHHHHHHHHHS???????S?SS?H--HHHHHHHHHHH-H???????????????????????-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------???-----------?----------------------------------------------------------------------------------- 3IF8|A PF09827.4_CRISPR_Cas2_seed 233 137 !Q:1,32|40,41|49,55|70,70|81,81|84,84|90,90|101,104|108,110|112,114|122,124|128,129 Q:0,0|33,39|42,48|56,69|71,80|82,83|85,89|91,100|105,107|111,111|115,121|125,127|130,136 E--------------------------------EEEEEEE??TTSHHHH-------HHHHHHHHHHGGGE-EEEETTEEEE-EE?HHHHH-HHHHHHHHHS?---TTT--?E---EEEEEEE---TTG--GGGEEEE 4ES3|A PF09830.4_ATP_transf_seed 64 81 !Q:0,0|6,6|17,17|20,33|37,38|40,41|52,52|63,63|68,70|79,79 Q:1,5|7,16|18,19|34,36|39,39|42,51|53,62|64,67|71,78|80,80 ?EEEEE?SSEEEEEEBS?SB?------------?TTT??B??GGGGGTEEEE?SHHHHHHHHH?THHH---HHHHHHHB?B 4I5T|A PF09832.4_DUF2059_seed 125 71 !Q:0,0|9,9|18,20|53,53|59,62 Q:1,8|10,17|21,52|54,58|63,70 ?HHHHHHHH-HHHHHTTS--?HHHHHHHHHHHHSHHHHHHHHHHHHHHHHHHH-HHHHH----HTTTHHHH 2X3O|A PF09836.4_DUF2063_seed 112 109 !Q:0,46|72,72|89,90|93,93|95,95 Q:47,71|73,88|91,92|94,94|96,108 ????????????????--??-------------------????????HHHHHHHHHHHHHHHHHTTTGGGGS?HHHHHHHHHHHHHSGG--GG?S?GGGHHHHHHHHHH 3DEE|A PF09837.4_DUF2064_seed 93 177 !Q:2,10|25,28|38,55|58,58|66,68|84,84|86,93|97,97|99,99|105,105|108,108|111,112|126,134|137,138|158,159|161,166|172,173 Q:0,1|11,24|29,37|56,57|59,65|69,83|85,85|94,96|98,98|100,104|106,107|109,110|113,125|135,136|139,157|160,160|167,171|174,176 HH---------HHHTTSSSEEEEEE????TTHHHHHHH------------------HH?TTSEEEE?-?SSSHHHHHHHHHHHH-H--------HTT?S-EEEEE?SS?TT??HHHHHHHHHHTTT?--------SE--EEEEBTTSSEEEEEEEGGG??G------GGGTT??TTT 3CGX|A PF09843.4_DUF2070_seed 41 205 !Q:11,17|21,25|30,31|41,43|48,48|51,51|65,68|73,77|86,86|94,94|97,100|113,127|134,136|138,139|152,154|161,161|163,167|179,180|185,187|190,193|202,204 Q:0,10|18,20|26,29|32,40|44,47|49,50|52,64|69,72|78,85|87,93|95,96|101,112|128,133|137,137|140,151|155,160|162,162|168,178|181,184|188,189|194,201 HHHHGGGEEEE-------EEE?????SSSS??HHHHHHHTT???EEEE?TT?EEEETTEEEEEEE?-??SSTT?????BEEEEEEE-TTEEEEE?TT????STTHHHHHHHHH???------------SEEEEE???S??BHHHHHGGGSSS???HHHHHH?B?????HHHHHHHHHHH??SEEE---EE????SGGGGGTS??? 4JO0|A PF09850.4_DUF2077_seed 122 253 !Q:0,2|20,21|23,27|29,29|39,40|50,50|55,62|75,75|84,84|86,101|107,107|115,115|117,117|131,132|137,138|153,162|166,169|181,181|184,215|218,252 Q:3,19|22,22|28,28|30,38|41,49|51,54|63,74|76,83|85,85|102,106|108,114|116,116|118,130|133,136|139,152|163,165|170,180|182,183|216,217 ???HHHHHHHHHHHHHHHHT--T?????H-HHHHHHHHH--HHHHHHHHH-HHTT?------?HHHHHHHHHHHH-HHHHHHHH-T??----?????---??HHHHS?HHHHHHS?S?HHHHHHHHHHHHH--TSSS??HHHHHHHHHHHHTT?????---??SSS?--?HHHHHHHHHHT?TT?-------------------????????????SS???-???---------------------------- 4ACK|A PF09861.4_DUF2088_seed 50 245 !Q:4,5|11,12|20,32|44,44|48,49|57,59|61,61|68,68|72,75|77,83|97,97|99,99|102,103|110,110|114,117|126,132|140,143|148,149|152,152|162,162|164,177|180,180|191,191|200,201|221,221|230,230|232,233|241,241|245,245 Q:0,3|6,10|13,19|33,43|45,47|50,56|60,60|62,67|69,71|76,76|84,96|98,98|100,101|104,109|111,113|118,125|133,139|144,147|150,151|153,161|163,163|178,179|181,190|192,199|202,220|222,229|231,231|234,240|242,244 ETTE--EEEEE??GGGEEEE?????????????HHHHHHHHHHS?BSS??HHHHTTT?--S?EEEEEE?TTS?-??H-------HHHHHHHHHHHHT-T?TT??EEEEEE?TTS????HHHHHHHH?------HHHHHHS----EEEE??TT?GGGEEEEEE?T--------------TS?EEEEEHHHHH?SEEEEEEE??EETTTEESSGGGGTTTTTB?HHHHHHTT?H--HHHHSTT?STT- 2YJG|A PF09864.4_MliC_seed 101 112 !Q:4,8|11,14|28,28|30,34|43,45|54,56|63,69|73,73|78,78|80,80|83,86|88,88|95,105|107,109 Q:0,3|9,10|15,27|29,29|35,42|46,53|57,62|70,72|74,77|79,79|81,82|87,87|89,94|106,106|110,111 EEET-----TS---?EEEEEEEEETTEE-E-----EEEEEETT---EEEEEEEE?-?SSSEEE-------EEB-TEEE-E-EE----T-TEEEEE???????????E---EE 3OE3|A PF09867.4_DUF2094_seed 33 148 !Q:4,5|8,8|11,11|16,17|38,39|52,54|60,60|66,68|78,79|81,81|85,85|87,88|96,96|100,100|102,104|111,111|130,131|133,134|144,147 Q:0,3|6,7|9,10|12,15|18,37|40,51|55,59|61,65|69,77|80,80|82,84|86,86|89,95|97,99|101,101|105,110|112,129|132,132|135,143 EEEE??TT?SS?EEES??HHHHHHHHHHHHHHHHHHHH--HHGGGHHHHHHH???EEEEE?TTSSS---SSEEEEEEE??B?TTS?B??EEEEEEE?TTB?H---HHHHTS?SHHHHHHHHHHHHTTSTT??H--HHHHHHHHT???? 2QNU|A PF09891.4_DUF2118_seed 9 172 !Q:0,3|10,12|14,29|31,31|45,46|49,52|62,65|76,76|78,78|83,83|85,86|95,95|98,98|100,100|106,106|113,116|121,121|124,124|131,131|134,135|141,141|156,159|171,171 Q:4,9|13,13|30,30|32,44|47,48|53,61|66,75|77,77|79,82|84,84|87,94|96,97|99,99|101,105|107,112|117,120|122,123|125,130|132,133|136,140|142,155|160,170 ????EEEEET???S----------------S?EEEEEGGGTEEEE??TT????SSSEEEEEE????GGGGEETTEE?S?EEEE?T--TSSEEEEE?TT?B?EEEEE?SSEEEE????SEEE?TT?EEEEEE?TT??EEEEE?SSSEEEEEEEEETT----EEEEEEEEEEE? 3D4R|A PF09897.4_DUF2124_seed 17 160 !Q:14,19|22,22|26,26|31,31|50,51|60,60|64,64|69,69|77,79|84,88|105,106|122,123|145,146|156,156 Q:0,13|20,21|23,25|27,30|32,49|52,59|61,63|65,68|70,76|80,83|89,104|107,121|124,144|147,155|157,159 EHHHHHHHHHHHHT------TT?SEE-EEEE?TTTTHHHHHHHHHHTTTS--EEEEEETT?GGG?EEEE-EETTEEE---EEEE????-EEEEEEEGGGGSTTTS??HHHHHHHHHHHEEEE--EEEEEEEETTHHHHTTHHHHS??SEEEEEEEE-EEE 2R47|A PF09904.4_HTH_43_seed 22 92 !Q:0,0|20,23|32,34|50,50|56,58|61,62|64,65|72,72|76,76 Q:1,19|24,31|35,49|51,55|59,60|63,63|66,71|73,75|77,91 ?HHHHHHHHHHHHHHHHHHS??-?HHHHHHHH???HHHHHHHHHTGGGGT?EEEEE?-?TT??S??EEEEEE?TTB?HHHHHHHHHHHHHHH 3KE2|A PF09905.4_DUF2132_seed 80 65 !Q:0,0|3,3|8,9|22,23|40,41 Q:1,2|4,7|10,21|24,39|42,64 ?SS?TTSS??HHHHHHHHHHHT-?HHHHHHHTTSSSTTSS??HHHHHHHHHHSHHHHHHHHHHHH 2JVW|A PF09917.4_DUF2147_seed 158 172 !Q:1,1|5,10|15,16|19,19|25,25|28,32|35,37|46,59|62,68|70,70|73,73|78,82|97,97|102,102|107,114|136,141|144,145|147,147|153,154|166,166 Q:0,0|2,4|11,14|17,18|20,24|26,27|33,34|38,45|60,61|69,69|71,72|74,77|83,96|98,101|103,106|115,135|142,143|146,146|148,152|155,165|167,171 E-EEE???---BTTB??EE-EEEEE-ET-----TE---EEEEEEEE--------------TT?--????B?TT?SSGG-----GTTSBSSSSEEEEE-EEEE-ETTE--------EEEEEEEETTTTEEEEEEEEE-----?TT--S?EEEEE--ESSTTSSSEEE-EEEEE 4INN|A PF09924.4_DUF2156_seed 156 424 !Q:4,9|13,13|25,26|31,33|37,40|46,50|61,62|65,68|70,73|75,75|91,91|94,95|101,101|111,111|116,116|122,122|126,126|138,141|159,162|164,164|166,166|171,176|199,199|201,202|222,222|224,226|231,232|236,237|240,271|281,281|285,288|300,300|303,304|317,319|324,325|328,336|340,398|401,401|412,413|418,419 Q:0,3|10,12|14,24|27,30|34,36|41,45|51,60|63,64|69,69|74,74|76,90|92,93|96,100|102,110|112,115|117,121|123,125|127,137|142,158|163,163|165,165|167,170|177,198|200,200|203,221|223,223|227,230|233,235|238,239|272,280|282,284|289,299|301,302|305,316|320,323|326,327|337,339|399,400|402,411|414,417|420,423 HTTS????--GGG?HHHHHHTHHHH??EEEE---ETT----EEEEE-----EEETTEEEEE??EE----S----S?HHHHHHHHHHHHHHH-TS??EEEEE?HHHHHHHHH-HSTT?EEEEE?GGG?EEEEEHHHHHH??--SGGGHHHHHHHHHHHHH---?T-T?EEEE?----?GGGHHHHHHHHHHHHHHHTTTT?H--HHHHHHHHHHHHHHTHHHH-T--?EEEE--EEE--TT--------------------------------EEEEEEEEE-EEE----TTEEEEEEEEE?TT--STTHHHHHHHHH---HHHS?-TT-------??EEE-------------------------------------------------------????TT?HHHHHHHHHT??SEEE??EEEE 2HQY|A PF09936.4_Methyltrn_RNA_4_seed 28 191 !Q:9,9|14,14|17,17|21,25|41,41|48,50|73,73|103,104|109,110|113,116|119,119|121,121|130,130|133,134|136,136|142,143|146,148|155,155|157,157|161,162|167,168|171,175 Q:0,8|10,13|15,16|18,20|26,40|42,47|51,72|74,102|105,108|111,112|117,118|120,120|122,129|131,132|135,135|137,141|144,145|149,154|156,156|158,160|163,166|169,170|176,190 TTSEEEEEE?SSEE?TT?SEE?????HHHHHHHHHHHHHTT?SEEEEE???HHHHHHHHHHHHHHHTSGGGGT?SSSHHHHTTEEEESSHHHHHHHHHHHHSS??EEEE??SS-?-?SS?B?HHHHHHHH-HH??S?EEEEE??TT???HHHHTT?S-EEB??TTTT--SS?????HHHHHHHHHHHHTTT 3DCM|X PF09940.4_DUF2172_seed 18 407 !Q:0,0|9,9|16,18|29,29|33,33|41,41|46,46|49,51|67,68|74,75|77,78|80,80|84,87|90,91|98,99|112,112|115,115|125,128|132,132|140,143|145,145|167,168|170,170|179,179|191,191|198,198|205,206|208,209|213,214|219,220|224,227|244,244|246,246|251,253|255,256|269,271|279,279|282,283|296,297|318,319|323,323|326,327|330,332|336,352|356,364|372,372|387,388|404,404 Q:1,8|10,15|19,28|30,32|34,40|42,45|47,48|52,66|69,73|76,76|79,79|81,83|88,89|92,97|100,111|113,114|116,124|129,131|133,139|144,144|146,166|169,169|171,178|180,190|192,197|199,204|207,207|210,212|215,218|221,223|228,243|245,245|247,250|254,254|257,268|272,278|280,281|284,295|298,317|320,322|324,325|328,329|333,335|353,355|365,371|373,386|389,403|405,406 ?EEEEEETT?EETTEE???EEEEEEEEEE?TTS?EEEETTT?GGGB?BT???EEEEEEHHHHGGGEE??TTSTT??B??B?SSS????EE??HHHHHT??SSEEEEEEEEEE-ES?EEEEEEEEE??--SSS?EEEEEEE????S?TTTTHHHHHHHHHHHHHHTTS??S-SEEEEEEE?TTHHHHHHHHH?GGGGGG-EEEEEE??S??SSS-?EEEE??TTS----SSHHHHHHHHHHHHSS-S?EEEE???S-?SSTHHHHTSTTT???EEEEESS?TT-?TTTTBTTSSGGG??HHHHHHHHHHHHHHHHHHHH??EEE-ES??SS???TTS?????????????-???HHH---------HHHHHHH?EEEEEHHHHHHHHT??HHHHHHHHHHHHHTT?EE 3K9T|A PF09966.4_DUF2200_seed 37 113 !Q:22,23|36,38|49,50|59,59|61,63|69,70|81,82|85,86|105,106 Q:0,21|24,35|39,48|51,58|60,60|64,68|71,80|83,84|87,104|107,112 GGGGSBHHHHHHHHHHHHHHTT??HHHHHHHHHHHH???HHHHHHHTTS??BHHHHHHT?S???GGGGG??SEETTEEGGG??SH--HHHHHHHHHHHHHHHHTT??HHHHHH 3C9P|A PF09968.4_DUF2202_seed 12 184 !Q:26,31|40,40|58,73|75,75|77,78|82,83|102,102|122,122|129,131|133,135|164,168|172,172|183,183 Q:0,25|32,39|41,57|74,74|76,76|79,81|84,101|103,121|123,128|132,132|136,163|169,171|173,182 HHHHHHHHHHHHHHHHHHHHHHHHHH?----?HHHHHHHH-HHHHHHHHHHHHHHHTT?-------------??S?S??STT??SSHHHHHHHHHHHHHHTS?HHHHHHHHHHHHHHHHHHH-HHHHTT???H---HHHHHHHHHHHHHHHHHHHHHHHHHHTT?????SSS?HHHHHHHHTS? 3Q4Q|A PF09981.4_DUF2218_seed 39 96 !Q:5,6|29,29|37,37|39,42|45,45|51,52|89,92|94,96 Q:0,4|7,28|30,36|38,38|43,44|46,50|53,88|93,93 EEEEE??SSHHHHHHHHHHHTTTSSEEEE?SSEEEEE?S----SS?EEEEE--ETTEEEEEEEESSHHHHHHHHHHHHHHHHHTSTTSS-???B??- 2JPI|A PF09982.4_DUF2219_seed 67 405 !Q:7,12|18,19|35,69|84,86|91,95|100,101|105,107|126,130|142,142|147,147|158,158|162,172|174,175|180,180|182,183|196,197|200,208|227,234|251,251|257,260|264,265|268,294|315,315|319,319|322,330|333,341|343,343|358,361|363,363|371,374|379,380|385,392|404,404 Q:0,6|13,17|20,34|70,83|87,90|96,99|102,104|108,125|131,141|143,146|148,157|159,161|173,173|176,179|181,181|184,195|198,199|209,226|235,250|252,256|261,263|266,267|295,314|316,318|320,321|331,332|342,342|344,357|362,362|364,370|375,378|381,384|393,403 HHHHHHH-----?HHHHH??SEEEEEEEEEEEESS-----------------------------------SSEEEEEEEEEEEE???GGGG-----GSSS??TTS???EEEEEEEEEEEEEEETTE-----EEEEEEEEEEE-SGGG?HHHHHHHHHH-HHT-------????G--GGGG?B??EEEEEEEEEEEE??EE---------EETTEEEEEEEEEEEEEE--------SSEEEEEEEEEEEEES?HHHHT????GGG??TT???????--------------------SEEEEEEEEEEEEEEEEEHH-HHS?BT---------TT?????---?B?SEEEEEEEEEEEEE----T-TEEEEEE----EEEE??SBTT???-----EEEEEEEEEEE? 3FID|A PF09985.4_DUF2223_seed 16 286 !Q:6,7|10,11|17,17|19,20|26,27|29,30|34,34|56,60|62,64|67,67|78,78|80,80|83,83|86,86|88,93|97,97|101,102|105,106|114,114|117,131|133,134|138,138|142,142|144,149|152,153|161,161|177,178|182,182|192,193|201,201|203,204|214,214|229,230|232,232|238,238|241,242|245,247|251,253|256,259|265,265|268,270|278,282|285,285 Q:0,5|8,9|12,16|18,18|21,25|28,28|31,33|35,55|61,61|65,66|68,77|79,79|81,82|84,85|87,87|94,96|98,100|103,104|107,113|115,116|132,132|135,137|139,141|143,143|150,151|154,160|162,176|179,181|183,191|194,200|202,202|205,213|215,228|231,231|233,237|239,240|243,244|248,250|254,255|260,264|266,267|271,277|283,284 EEEEEE??SS??STTTT?B??SSTTS-?T--TTT?EEEEEEEEETTEEEEEEEESS?????S??-SS?SSEEEEEEEE?S?SS?EE?S------GGG?EEE--SS??SEEEEEE?ST---------------T??EEE?TTS?E------EE??EEEEEGG-GTEEEEEEEGGGSSS??TTT?EEEEEEEEB??GGGSTTS-B??EEEHHHHHH?SSHHHHHHSEEEES??B?SSSTT?BS??SS???SEE???TT--??HHHHT?GG---GSSSEEE---??EE? 1UG9|A PF09992.4_DUF2233_seed 288 409 !Q:0,1|8,28|36,53|57,58|62,68|71,72|77,92|95,96|103,111|115,115|120,132|142,147|154,154|156,157|161,174|178,178|180,191|195,201|203,218|224,242|248,248|255,260|264,264|272,275|277,278|280,283|287,292|294,295|302,302|305,306|309,314|316,316|318,318|320,320|322,326|330,332|336,337|341,341|343,357|359,359|363,363|365,365|367,368|370,370|372,377|382,400 Q:2,7|29,35|54,56|59,61|69,70|73,76|93,94|97,102|112,114|116,119|133,141|148,153|155,155|158,160|175,177|179,179|192,194|202,202|219,223|243,247|249,254|261,263|265,271|276,276|279,279|284,286|293,293|296,301|303,304|307,308|315,315|317,317|319,319|321,321|327,329|333,335|338,340|342,342|358,358|360,362|364,364|366,366|369,369|371,371|378,381|401,408 ??EEEEEE------?-----?---?----EETTTTE------------------ESS-?EEE-------TT--EEEE???------------?TT??EEEEEE---------TTS?EEEE-------------EHHHHHTTG------GGEEEE-E--EES-----------?--EEE-E------------TTE-------E?-------?----?-?TTSGG-------------------GGSSB?EEEEEE?-----TTS-SEEEEEE----E??S--??STT--????B-?HHHHHH-HH--HH------H-T?S-E-----EEE???GGG??EEE?E---------------E?TTS?E-E??B?S??----TTTT---------------????BSEEEEEE 3OHG|A PF09996.4_DUF2237_seed 79 117 !Q:0,0|2,2|8,13|16,17|25,28|31,31|34,34|41,42|54,57|59,59|66,69|72,72|89,92|94,94|99,99|107,107|116,116 Q:1,1|3,7|14,15|18,24|29,30|32,33|35,40|43,53|58,58|60,65|70,71|73,88|93,93|95,98|100,106|108,115 ?B?TTSSB??????SS??STTSSSS????SS?SS?EEEEEE??HHHHHHHHHHT????S?BTTTTB????TT?EEEEESHHHHHHHHTT????B?GGGS?GGGGGTS?HHHHHHTS? 2LQ3|A PF10000.4_ACT_3_seed 48 79 !Q:0,2|13,13|18,18|21,21|28,33|35,35|43,44|46,46|69,73|75,75 Q:3,12|14,17|19,20|22,27|34,34|36,42|45,45|47,68|74,74|76,78 ???SHHHHHHHHT?EEEE?SS?EEEEEE?-----S?GGGGGGG??S-EEEEETTEEEEEEEHHHHHHTT?-???S?EEE 1ZVP|A PF10014.4_2OG-Fe_Oxy_2_seed 113 250 !Q:7,8|11,12|14,15|18,20|25,25|38,41|45,56|60,60|63,64|67,67|69,70|72,72|77,79|81,84|109,117|137,144|147,147|150,151|157,157|165,165|169,171|174,175|179,189|201,203|207,207|214,215|223,224|229,229|232,232|236,240 Q:0,6|9,10|13,13|16,17|21,24|26,37|42,44|57,59|61,62|65,66|68,68|71,71|73,76|80,80|85,108|118,136|145,146|148,149|152,156|158,164|166,168|172,173|176,178|190,200|204,206|208,213|216,222|225,228|230,231|233,235|241,249 TGGGGGS-?EE??S??SS?-?EEEE?BEEEEEEETTEE----EEE?-------????EEE?SS--TT?S--S?SEEE???B??--HHHHTSHHHHHHHHHHHHHHHHHS-------??GGGEEEEEEEEEEEETTSS?---????TT?SB??SSSEE-EEEEEEE-ESE---EE??EEE-----------EETTSSEEEEE???STT?EEEEET--TTEEEEE??EEES?TT?TTS?---?EEEEEEEEE 3PL0|A PF10021.4_DUF2263_seed 20 186 !Q:8,18|25,25|29,29|33,33|41,41|45,45|49,49|54,56|63,68|71,72|79,80|86,89|96,103|106,107|113,114|126,127|146,148|152,154|162,163|166,167|169,169|171,173|184,184 Q:0,7|19,24|26,28|30,32|34,40|42,44|46,48|50,53|57,62|69,70|73,78|81,85|90,95|104,105|108,112|115,125|128,145|149,151|155,161|164,165|168,168|170,170|174,183|185,185 HHHHHHHH-----------HHTEEE?TTS?EEE?HHHHHHH-HHT?EEE?HHHH---HHHHHT??????SS??EEEEES??HHHHH----HHHHHH-------?SS??EEEEE??SSSTTTTGGGT??SHHHHHHHHBSHHHHHTT?--HHH---HHHHHHH??TT??S?E---EEEEEEEEEE?T 3SIH|A PF10025.4_DUF2267_seed 135 199 !Q:3,3|15,30|50,50|62,76|86,90|92,93|97,110|124,138|141,142|147,151|154,154|171,171|176,176|181,181|185,190|192,192 Q:0,2|4,14|31,49|51,61|77,85|91,91|94,96|111,123|139,140|143,146|152,153|155,170|172,175|177,180|182,184|191,191|193,198 HHH-HHHHHHHHHHT?-??------------HHHHHHHHHHHHHHHHTTS?HHHHHHHHTTS--------------?HHHHHHHHT-----T??TTS????-?-------?SHHHHHHHHHHTS---------------EE--TTEE-----SS?HHHHHHHHHHHHHHHS?HHHH-HHHH-HTS?-----H-HHHTTS 2YSK|A PF10033.4_ATG13_seed 38 387 !Q:15,92|103,105|109,126|135,135|138,139|142,142|148,148|152,152|160,182|185,185|194,194|199,227|232,235|260,263|265,297|305,313|318,321|326,326|329,335|338,343|345,349|351,353|358,360|364,366|383,384 Q:0,14|93,102|106,108|127,134|136,137|140,141|143,147|149,151|153,159|183,184|186,193|195,198|228,231|236,259|264,264|298,304|314,317|322,325|327,328|336,337|344,344|350,350|354,357|361,363|367,382|385,386 HHHHHHHHHHHHHHT??---------------------------?????????????????-------------------?????---?????HHHHHHHHHS-??TTS--------------????EEEEEEEE?TT??TT?EEEEE?TTS?EEEEEET-----------------------TS?SEEEEEEE-EEEE?--------????????????????????HHHH----HHHHHHHHHHHHHHSHHHHHHHHH----T??????????---------------------??EEEEEEE---------ETTS????TTSB?TT???---?TT??????T-----T???TTEE---EEE???EEETTEEEEEEEEEES??EE 4J2G|A PF10035.4_DUF2179_seed 189 61 !Q:0,2|6,6|8,8|15,18|20,21|29,29|44,44|47,47|52,60 Q:3,5|7,7|9,14|19,19|22,28|30,43|45,46|48,51 ???EEE-E?EESSSS----S??EEEEEEE?HHHHHHHHHHHHTT?TT?EEEE-???????? 3HLU|A PF10040.4_DUF2276_seed 63 172 !Q:7,8|15,15|25,28|30,30|33,34|36,36|40,40|54,72|82,82|88,88|95,95|97,100|107,119|132,140|158,159|167,167|169,169 Q:0,6|9,14|16,24|29,29|31,32|35,35|37,39|41,53|73,81|83,87|89,94|96,96|101,106|120,131|141,157|160,166|168,168|170,171 EEEEEEE??BGGGGS?GGGTTTTTT????B?SS??H-HHH-HHHHHHHHHHHTT-???--------------?HHHHHHHHH-HHHHH?EEEEEE-E----EEEEEE?---?????????EEEEEEEEEEEE??------?HHHHHHHHHHHHHHHHH??STTGGGT?S?EE 4ILR|A PF10052.4_DUF2288_seed 36 94 !Q:0,0|9,11|14,14|26,26|31,31|35,35|47,47|63,64|72,72|76,76|78,78|84,84|87,87|92,92 Q:1,8|12,13|15,25|27,30|32,34|36,46|48,62|65,71|73,75|77,77|79,83|85,86|88,91|93,93 ?HHHHHHTT???EE?GGGGHHHHHTT?EEEE?SSS?HHHHHHHHHTT?HHHHHHHHHHTSEEE??HHHHHHH-HHH?S?EEEEE?SS?EEEE?S 2LV5|A PF10054.4_DUF2291_seed 21 221 !Q:0,39|58,59|73,73|84,86|89,89|107,111|119,119|123,123|126,126|133,137|146,146|148,149|153,153|187,188|191,191|205,208 Q:40,57|60,72|74,83|87,88|90,106|112,118|120,122|124,125|127,132|138,145|147,147|150,152|154,186|189,190|192,204|209,220 ------------------------??????--------??HHHHHHHHHHHHHHHHHH??SEEHHHHHHHHHH?HHHHHHHHEE?-?TT?SEEEEEEEEEEEEEEEE-----TTEEEEE?SSS?SS?SEEEES?--??TTHHHHHH?S??GGG?SSHHHHHHHHHHHHHHHHHHTHHHHHHHHHTTT??TT?EEEEEEEEEEETT????SSEEEEEEEEEE 2F4I|A PF10061.4_DUF2299_seed 13 145 !Q:10,10|15,20|31,31|34,35|37,37|47,47|59,60|71,71|90,90|92,92|98,98|100,100|103,105|118,121|145,145 Q:0,9|11,14|21,30|32,33|36,36|38,46|48,58|61,70|72,89|91,91|93,97|99,99|101,102|106,117|122,144 HHHHHHHHTT?EEEE---???TTEEEEEEEE?ST--T?EEEEEEESS?SSEEEEEEEEE??TTHHHHHHHS?HHHHHHHHHHHHHHHTTT-T?EEEEE?T-TS???EEEEEEEEEGGG--??HHHHHHHHHHHHHHHHHHHHHHH- 3CXJ|A PF10075.4_PCI_Csn8_seed 48 199 !Q:1,2|20,20|31,31|38,57|74,74|80,83|87,87|90,97|107,108|124,129|133,133|144,146|149,155|165,165|167,167|170,184|187,189|196,198 Q:0,0|3,19|21,30|32,37|58,73|75,79|84,86|88,89|98,106|109,123|130,132|134,143|147,148|156,164|166,166|168,169|185,186|190,195 G??HHHHHHHHHHHHHTTTS-THHHHHHHTS?HHHHTS--------------------TTHHHHHHHHHHHHTT?HHHHH----HHS?TT-----?--HHHHTSTTH--HHHHHHHHHHHHHHH?-----SEE?HHHHHHHTTS?-?HH-------HHHHHHHHH-T?EE--?--------????EE???HHHHTS??? 4BGR|T PF10090.4_DUF2328_seed 59 203 !Q:12,12|16,18|49,50|53,56|74,74|76,80|86,88|90,90|93,93|98,101|115,115|118,119|122,122|126,127|146,149|159,165|168,168|187,187 Q:0,11|13,15|19,48|51,52|57,73|75,75|81,85|89,89|91,92|94,97|102,114|116,117|120,121|123,125|128,145|150,158|166,167|169,186|188,202 HHHHHHHHHHHH?STT---GGGHHHHHHHHHHHHHHHHHHHHHHHHHTT??SS-???EEHHHHHHHHHHHHTTS-S-----SEEEE???S?EE?HHHH----HHHHHHHHHHHHT?TT??EE-EEE--EEEETTEEEEEEEEESTT????HHHHHHHTT??--??-SS?HHHHHHHHHHHHHHHHTT?EEEEEEETTEEEEEE 4FMT|A PF10091.4_Glycoamylase_seed 79 292 !Q:0,1|3,4|19,19|23,25|34,34|51,51|55,55|59,62|65,67|79,80|88,91|94,94|110,113|117,117|120,121|124,124|127,127|130,133|140,155|157,157|161,162|168,181|183,183|185,185|197,197|210,210|219,225|230,230|232,232|236,236|239,255|258,260|278,278|281,281|290,290 Q:2,2|5,18|20,22|26,33|35,50|52,54|56,58|63,64|68,78|81,87|92,93|95,109|114,116|118,119|122,123|125,126|128,129|134,139|156,156|158,160|163,167|182,182|184,184|186,196|198,209|211,218|226,229|231,231|233,235|237,238|256,257|261,277|279,280|282,289|291,291 ??B??SSSTTHHHHHHHHH?TTT???HHHHHHTT-SGGGTTEEEEEETTEE-EEE?BTT----BS???GGGGTGGGSSS??TTEEBTT----BS?HHHHHHHHHHHHHHH----HHH?TT??TT?BT-TB????EEEETT----------------E-EEE??SSGGG------------??S?B?HHHHHTTTTTS-HHHHHHHHHHHH-HTGGGTEE-------TTEE?S?BBT-TT-----------------TB???EEEHHHHHHHHHHHHHH-HH?HHHHHHHT?H 3EU8|A PF10103.4_DUF2342_seed 44 414 !Q:0,2|6,6|20,25|27,28|30,30|55,57|60,66|71,72|97,144|163,164|174,192|197,197|210,211|250,300|333,333|349,349|364,370|386,386|396,396|401,402|408,408 Q:3,5|7,19|26,26|29,29|31,54|58,59|67,70|73,96|145,162|165,173|193,196|198,209|212,249|301,332|334,348|350,363|371,385|387,395|397,400|403,407|409,413 ?-?HHH-HHHHHHHHHTGGG------S??S?HHHHHHHHHHHHHHHHHHHHHHHT???SS?----??EEEE??HHHHHHHHHHHHHHTTHHHHHHHH???????????-------------------------------??????HHHHHHHHHHHHHHHHTT??BTTSSHHHH???-------------???EEEE?HHHHHHHHHHTT??HHHHHHHHHHHHHHHHHHHHTSTHHHHHHHHHHHHHHT?????--??????????????????????-------------?????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?TTHHHHHHHHHHHHH-HHHHHHHHHHHHTT???????SSHHHHHHHHHHHHH?HHHHGGGGS?GGGS??HHHHH?HHHHH 3CMN|A PF10108.4_DNA_pol_B_exo2_seed 36 259 !Q:1,1|6,11|17,17|20,24|34,37|43,43|45,50|64,65|68,70|94,96|103,105|117,123|141,143|145,147|157,164|175,175|180,184|199,209|225,226|231,231|234,236|238,244|247,247|249,251 Q:0,0|2,5|12,16|18,19|25,33|38,42|44,44|51,63|66,67|71,93|97,102|106,116|124,140|144,144|148,156|165,174|176,179|185,198|210,224|227,230|232,233|237,237|245,246|248,248|252,258 S?TTTS?---??EEEEE-ET-----TEEEEEESS????TTEEE?S-----?HHHHHHHHHHHHH--HH?-?SEEESSTTTTHHHHHHHHHHHTT???TTSTTS???EEEEETTEEEE-------BTTBEEEEHHHHHHTSS-??S???HHHHHHHHS??-?????HHHHHHHHHS?SSTT-----HHHHHHHHHHHHHH-----------HHHHHHHHHHHHHHH--HTTS?HH---H-------HT-T-??HHHHHHH 4FM2|A PF10120.4_Aldolase_2_seed 52 184 !Q:13,17|20,21|24,24|26,26|31,32|36,37|48,49|53,53|60,60|62,62|67,68|82,82|85,86|92,94|110,110|115,116|121,121|130,130|144,145|148,148|152,153|157,158|163,164 Q:0,12|18,19|22,23|25,25|27,30|33,35|38,47|50,52|54,59|61,61|63,66|69,81|83,84|87,91|95,109|111,114|117,120|122,129|131,143|146,147|149,151|154,156|159,162|165,183 HHHHHHHHHHHHT??--?TT??SS?B?EEEE??TTS??SGGGEEEETT?-EEE?SSSEEE?S?EEET??SHHHHHHHHHHTT?TT??EEEEE???HHHHHHHHHHHHHTT?EEEE??GGGS?HHHHHSTT?HHHHHHHHHHHHS--SS?EEE--EEE??BTTB??EEEEEESSHHHHHHHHHHT 2PHP|A PF10140.4_YukC_seed 16 367 !Q:6,9|21,21|27,27|32,32|42,43|46,46|56,56|59,60|76,77|83,86|93,93|96,97|102,103|112,112|114,115|133,133|136,136|140,140|149,151|160,160|171,171|187,366 Q:0,5|10,20|22,26|28,31|33,41|44,45|47,55|57,58|61,75|78,82|87,92|94,95|98,101|104,111|113,113|116,132|134,135|137,139|141,148|152,159|161,170|172,186 EEEGGG????SGGGGGGGGGS?SSSEE-EEEE?SSEEEEEEE??TT?EEHHHHHTS?HH--HHHHHHHHHHHHHSS??SSSEE????GGGEEE?TT??EEES??EETTTBSS?S??HHHHHHHHHHHHHHHTT?SS?HHH-HHHHTTTS???HHHHHHHH?SSHHHHHHHH-HHHHHHHHHHHHHTT??????????-------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 4ANN|A PF10143.4_PhosphMutase_seed 92 270 !Q:6,6|11,21|30,32|37,39|50,53|56,57|68,70|74,95|105,108|112,114|122,122|124,125|128,130|133,148|150,150|157,157|167,170|172,174|178,192|194,194|196,198|200,203|205,205|210,226|229,239|246,246|265,265 Q:0,5|7,10|22,29|33,36|40,49|54,55|58,67|71,73|96,104|109,111|115,121|123,123|126,127|131,132|149,149|151,156|158,166|171,171|175,177|193,193|195,195|199,199|204,204|206,209|227,228|240,245|247,264|266,269 HHTSEE-EEEE???????????TTHHHHTT??-HHHH???HHHHHHHHTT????TT-?EEEEEEEEEE---SSS----------------------SEEETTGGG??--TTH---HHHHHHT?E--EE---TT----------------E-EEEEEE?STTEEEEEE----E---STT----?---?------S?B?-?S??--S-STTS----------?-?????BS-----------SGGGHH-HHHHHHHHHHHHHHHHHT?HHHH 2ZKT|A PF10150.4_RNase_E_G_seed 173 357 !Q:0,0|3,3|9,9|11,17|19,19|23,24|26,27|30,40|43,46|50,74|77,94|97,97|103,104|126,126|131,133|135,142|148,151|161,162|172,176|189,190|194,194|198,198|201,202|205,206|209,215|217,217|219,219|226,226|235,236|241,241|243,245|248,248|255,255|258,258|265,276|301,302|309,312|332,332|335,335|338,343|353,354 Q:1,2|4,8|10,10|18,18|20,22|25,25|28,29|41,42|47,49|75,76|95,96|98,102|105,125|127,130|134,134|143,147|152,160|163,171|177,188|191,193|195,197|199,200|203,204|207,208|216,216|218,218|220,225|227,234|237,240|242,242|246,247|249,254|256,257|259,264|277,300|303,308|313,331|333,334|336,337|344,352|355,356 ?EE?SSEEE?T-------T?SSS-?B??TT????---????HH----HHH-------------------------HT?--?????-------???EE?TTGGG??HHHHHHHHHHHHHHHHHHHHT-TSSS?--S--------SEEEE????HHHHHHHHS??TTEEEEEES?----HHHHHHHHHHHH--TTT?GGG-GG--GE--EE??----?S-S?HHHHTT?HHHHHHTT-?SEEE?T---TS?EEEEEE?SS?EEEEEE????-?????--HHHHHHHHHHHHHHHHHHHHHHTT??EEEEEE????SSHHHHHHHHHHHHHHTSS?SS?EE?????-TTSEEEEEE??SS 2C0B|L PF10156.4_Med17_seed 28 811 !Q:0,219|229,233|241,242|268,268|276,296|303,307|312,325|340,347|349,354|387,397|401,465|475,475|478,482|484,492|499,499|508,510|512,513|516,518|521,523|528,528|532,532|537,553|555,563|565,565|568,568|571,571|574,577|582,582|586,586|588,589|594,603|605,605|608,611|614,614|647,648|652,652|655,655|662,668|676,687|690,690|694,709|743,745|747,771|806,806|810,810 Q:220,228|234,240|243,267|269,275|297,302|308,311|326,339|348,348|355,386|398,400|466,474|476,477|483,483|493,498|500,507|511,511|514,515|519,520|524,527|529,531|533,536|554,554|564,564|566,567|569,570|572,573|578,581|583,585|587,587|590,593|604,604|606,607|612,613|615,646|649,651|653,654|656,661|669,675|688,689|691,693|710,742|746,746|772,805|807,809 ???????---????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????-----------?????????------------????????????????????------------??????????HHHHHHHTS?????SSHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHH?SSHHHHH---------------------HHTTSH-----HHHT?????????---??HHHHHHHHHSHHHH--------H------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-----------HHH-----------------------------------------------------------------HHHHHHSSS?SS-----S???------EEEESS?SSSSEEEE???S??SS???SS???EEEE?TTS?EEEE?----------------S?????????B?SS?SS?EE????EEEE?TTS?S??EEEE-?????----S?SS????TT?HHHHHHHHHHHHHHHHHHHHHHHHHHHTTSSS??BTT-TB?EEEETT-------TTEEEEE?----------?TT?SEE??????------????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTT???S?-----------------------?GGGTTTTHHHHHHHHHHHHHHHHHHHHHHHHHHT?SSS? 4GWQ|B PF10163.4_EnY2_seed 24 106 !Q:9,11|16,17|51,65|67,67|71,72|89,89 Q:0,8|12,15|18,50|66,66|68,70|73,88|90,105 HHHHHHHHH---HHHT--THHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHH---------------H?TTT??HHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHH 3MHH|B PF10178.4_DUF2372_seed 8 111 !Q:7,9|16,22|24,24|27,28|30,38|42,43|49,54|58,61|82,82|90,90|93,94|109,110 Q:0,6|10,15|23,23|25,26|29,29|39,41|44,48|55,57|62,81|83,89|91,92|95,108 EEEESTT???EEEEEE-------E?SS??S---------SSS??EEEEE------EES?-??HHHHHHHHHHHHHHHHHTTS?EEEEEEE?SS??HHHHHHHHHHHHHT?? 2Z5E|A PF10185.4_Mesd_seed 7 194 !Q:4,4|20,21|27,32|34,34|36,40|42,46|50,51|53,54|61,64|66,67|74,75|78,78|80,80|84,87|103,104|122,122|144,145|149,150|155,162|167,167|173,173|176,176|187,188|191,193 Q:0,3|5,19|22,26|33,33|35,35|41,41|47,49|52,52|55,60|65,65|68,73|76,77|79,79|81,83|88,102|105,121|123,143|146,148|151,154|163,166|168,172|174,175|177,186|189,190 STTT?GGGTHHHHHHHHHHH--HHHHS??????S?S?????S?????SSS--S??SHHHHH????S??EEEEES--SS?S?HHH----HHHHHHHHHHHGGGS??EEEEEEETTEEEEEEES?SHHHHHHHHHHHHHSSEEEEE??SSS??SSSS????????HHHH-HHHHH?SS?SSSHHHHHHH??SS??? 2I9S|A PF10193.4_Telomere_reg-2_seed 31 155 !Q:1,3|13,22|24,24|39,46|63,66|69,70|89,119|126,126|134,135|137,139 Q:0,0|4,12|23,23|25,38|47,62|67,68|71,88|120,125|127,133|136,136|140,154 G???HHHHHHHHT??????---?S?SHHHHHHHHHHHHS???---??SSHHHHHHHHHHHHHH???-TT??TTTTHHHHHHHHHHHHHS-------------------------------GGGHHH-HHHHHTT--S???HHHHHHHHHHHHHHH 3O4Z|A PF10208.4_Armet_seed 8 159 !Q:0,1|20,23|39,39|51,51|55,58|78,78|85,85|95,98|104,104|109,109|122,124|127,127|147,148|150,152|154,155|157,158 Q:2,19|24,38|40,50|52,54|59,77|79,84|86,94|99,103|105,108|110,121|125,126|128,146|149,149|153,153|156,156 ??HHHHTTHHHHHHHHHHTT????STHHHHHHHHHHTTS?TTTTTTTTTTT?STT????TTHHHHHHHTTTSSTTTHH-HHHHHH?GGGTTTTTT??-?SGGGT?TTTS?HHHHHHHHHHHT???SS?SSHHHHHHHHHTTTTTTTT??T---T??S?? 2RQY|A PF10215.4_Ost4_seed 12 35 !Q:0,1|4,4|30,34 Q:2,3|5,29 ??SS?GGGHHHHHHHHHHHHHHHHHHHHTS????? 2LAT|A PF10224.4_DUF2205_seed 8 85 !Q:0,7|64,66|70,84 Q:8,63|67,69 ????????TTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHT???????????-??? 4BWD|A PF10232.4_Med8_seed 7 339 !Q:0,23|25,29|55,62|66,68|94,94|102,108|115,128|137,141|152,154|159,159|163,163|171,181|194,208|216,216|218,220|222,236|245,248|251,312|323,338 Q:24,24|30,54|63,65|69,93|95,101|109,114|129,136|142,151|155,158|160,162|164,170|182,193|209,215|217,217|221,221|237,244|249,250|313,322 ????????????????????????S?????TTHHHHHHHHHHHHHHHHHHHHHHH-------?TTS???HHHHHHHHHHHHHHHHHHHHHHHHT-HHHHHHH???????GGGTTT--------------TTHHHHHT?????TTHHHHHHHH---HHSS?SSS?THHHHHH-----------HHHHHHHHHHHH---------------HHHHHHH-H---H???????????????HHHHHHHH????SS?-------------------------------------------------------------HHHHHHHHHH???????????????? 4GWQ|C PF10240.4_DUF2464_seed 12 316 !Q:0,3|13,15|18,18|21,22|24,24|27,27|29,29|31,33|35,37|39,39|42,46|52,55|57,57|63,63|77,79|82,82|85,86|88,88|92,93|95,96|111,111|113,113|125,128|148,231|235,315 Q:4,12|16,17|19,20|23,23|25,26|28,28|30,30|34,34|38,38|40,41|47,51|56,56|58,62|64,76|80,81|83,84|87,87|89,91|94,94|97,110|112,112|114,124|129,147|232,234 ????EEEEESSTT???TT?EE??B?TT-S?B???S???T-TS?????EEEEE????S-TTGGG?EEEEEEEEEETTS???TT?EE??B?TTT??B??SSEEEEEEEEEGGG?S?EEEEEEEEETT????TTEEEEEEETTEEEEEEEE?-----------------------------------------------------------------?-----------------TTT?-------------------------------------------------------------------------------- 3TOW|A PF10250.4_O-FucT_seed 62 551 !Q:3,5|8,9|17,18|32,38|41,41|47,63|65,66|68,69|77,79|82,82|86,88|91,91|95,103|109,110|121,129|143,144|147,149|152,156|161,162|164,169|171,172|174,174|177,177|181,181|184,185|189,189|192,192|201,201|204,204|210,215|223,231|234,234|247,247|261,268|270,271|273,273|289,291|297,307|313,316|319,319|321,322|331,332|334,334|337,379|384,384|388,389|395,399|409,410|413,420|422,422|428,439|442,444|447,448|455,455|458,461|464,468|478,479|499,499|501,503|505,505|521,521|527,548|550,550 Q:0,2|6,7|10,16|19,31|39,40|42,46|64,64|67,67|70,76|80,81|83,85|89,90|92,94|104,108|111,120|130,142|145,146|150,151|157,160|163,163|170,170|173,173|175,176|178,180|182,183|186,188|190,191|193,200|202,203|205,209|216,222|232,233|235,246|248,260|269,269|272,272|274,288|292,296|308,312|317,318|320,320|323,330|333,333|335,336|380,383|385,387|390,394|400,408|411,412|421,421|423,427|440,441|445,446|449,454|456,457|462,463|469,477|480,498|500,500|504,504|506,520|522,526|549,549 EEE???TT??HHHHHHH--HHHHHHHHHHHHT-------TS?EEEEE---------------??B??S-?GGGSTTS???SB?GGG---TB?HHH---------HHTTS-?EEEHHHHHHH---------SSSSEEEEEEEEE??TT???TT?????EEEE??S------S??S?EE?TTS?EE??GGG?TT?EEEEEEEE-EE?SBGGG------GHHHHHH?--------TT?SEEEEESGGGSB?SSTTSHHHHHHHH--------T??B?HHHHHHHHHHHHHHH???TTTTT????-------SSGGG????TT?B??EEEEEEEE??T-TT-------------------------------------------TTTT?SSS??HHHHH-----HHHHHHHHH--HT?-------S?EEEEE??---------?HH---HH--HHHHHH?TT----EE?????HHHHHHHHH--HHHHHHHHHHHHTEEEEEB?T---T?HHHHHHHHHHHHHTB?GGGTS---------------------?B? 4AP5|A PF10258.4_RNA_GG_bind_seed 17 90 !Q:11,11|25,25|44,47|53,55|67,70|73,74|87,89 Q:0,10|12,24|26,43|48,52|56,66|71,72|75,86 HHHHHHHHHTT?TTHHHHHHHHHHH?HHHHHHHHHHHHHHHHHT????SSSSS???HHHHHHHHHHH---?SS??HHHHHHHHTSTT??? 2W4S|A PF10262.4_Rdx_seed 82 227 !Q:0,0|7,14|20,20|24,35|48,48|51,54|56,57|59,60|65,133|136,139|141,142|145,147|154,158|161,181|191,211|213,215 Q:1,6|15,19|21,23|36,47|49,50|55,55|58,58|61,64|134,135|140,140|143,144|148,153|159,160|182,190|212,212|216,226 ?EEEEEE--------ETTTT?HHH------------HHHHHHHHHHHT-TT----T?-S--EEEE---------------------------------------------------------------------EE----E?-TT?--EEEEET-----TE---------------------EEEEHHHHT---------------------S???HHHHHHHHHHH 2NPB|A PF10275.4_Peptidase_C65_seed 33 375 !Q:0,6|8,8|10,16|27,27|30,31|39,47|54,57|61,61|63,64|67,67|84,84|87,92|97,97|104,105|113,117|121,122|144,145|148,154|169,177|184,185|203,204|207,216|230,233|245,248|250,251|257,295|298,299|306,322|325,346|349,360|374,374 Q:7,7|9,9|17,26|28,29|32,38|48,53|58,60|62,62|65,66|68,83|85,86|93,96|98,103|106,112|118,120|123,143|146,147|155,168|178,183|186,202|205,206|217,229|234,244|249,249|252,256|296,297|300,305|323,324|347,348|361,373 ???????S-B???----EEGGGGGGGS?TT-?HHHHHHH---------HHHTTT--??EEE?B??SS?HHHHHHHHHHHHHHTT?HH------HHHH-HHHHHH--HHHHHHH-----HTT??HHHHHHHHHHHHHHHHHHHTT??HH-------HHHHHHTSHHHHHH---------HHHHHH--HHHHHHHHHTHHHHGGG??SS--------??HHHHHHHHTSSTT????HHHHHHHHHHH----T??EEEEE??------------------------------??----?SS??EEEEES-----------------TT-------------------???SE------------EEEEETTEEEEEE? 3VON|A PF10276.4_zf-CHCC_seed 37 63 !Q:9,18|21,25|28,33|43,44|49,50 Q:0,8|19,20|26,27|34,42|45,48|51,62 SSSEEEEEE----------SS-----TT------SEEEEEEEE??TTTS--EEEETTTTEEEE 2JRR|A PF10280.4_Med11_seed 25 204 !Q:35,56|95,170|174,175|177,177|179,183|197,197 Q:0,34|57,94|171,173|176,176|178,178|184,196|198,203 THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT---------------------?GGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS----------------------------------------------------------------------------SSS??S-S?????SHHHHHHHHHHHH-HHHHHH 4GWQ|A PF10282.4_Lactonase_seed 81 520 !Q:6,7|9,22|25,26|34,36|49,49|52,56|58,58|60,63|67,70|73,73|83,89|104,107|113,118|123,124|127,129|148,154|164,164|167,167|169,169|175,176|180,192|196,206|208,209|212,213|220,220|223,223|225,225|242,245|249,253|257,259|264,264|266,267|270,271|278,278|280,282|284,302|320,321|325,325|330,331|334,334|344,344|346,347|349,351|353,378|386,386|390,390|399,417|427,428|432,432|441,441|445,449|454,455|471,471|478,478|482,483|491,491|494,494|499,515 Q:0,5|8,8|23,24|27,33|37,48|50,51|57,57|59,59|64,66|71,72|74,82|90,103|108,112|119,122|125,126|130,147|155,163|165,166|168,168|170,174|177,179|193,195|207,207|210,211|214,219|221,222|224,224|226,241|246,248|254,256|260,263|265,265|268,269|272,277|279,279|283,283|303,319|322,324|326,329|332,333|335,343|345,345|348,348|352,352|379,385|387,389|391,398|418,426|429,431|433,440|442,444|450,453|456,470|472,477|479,481|484,490|492,493|495,498|516,519 EEEEEE??S--------------SS??EEEEEEE---ETTTTEEEEEEE-EE-----E?S????EEE---?TT?EEEEEEEET-------TEEEEEEEEEETTE----EEEEE------EEEE--ES???SEEEEETTTTEEEEEETT-------TTEEEEEEE?TT-S?EEEEE--EEE??------??--?SST-----------T-?SS??EEEEEE?TT-S?EEEEETTTTEEEEEEE---?TTS?----EEE---EEEE-E??TT??EEEEEE?T---T-------------------SSEEEEEETTTTEEEEE--EEE-TTTT--EE-EEEEEEESS?T--T-??S?---------------------?---EEEEEEE?TTS?EEEEEEET-------------------TTEEEEEEE-?GGG?EEEEEEEE?SSS?--??EEEE-?TTSSEEEEEETTTTE-EEEEEE?TTT??EEEEEEE-EE?TTEE-----------------EEEE 1RI6|A PF10283.4_zf-CCHH_seed 22 26 !Q:0,25 Q: ?????????????????????????? 2KQE|A PF10284.4_Luciferase_3H_seed 7 67 !Q:0,1|3,3|8,10|16,16|26,26|35,39|42,42|46,46|56,56 Q:2,2|4,7|11,15|17,25|27,34|40,41|43,45|47,55|57,66 ??T-TSBS???SSSSS?BTTTTGGGG-GGEETTEE?????SS?TTS?EEETTEEES?HHHHHHHHHT 1VPR|A PF10285.4_Luciferase_cat_seed 3 296 !Q:4,4|24,27|35,37|39,40|50,51|58,59|62,62|64,65|67,67|70,72|74,77|80,80|83,83|104,104|106,107|125,125|141,142|157,157|167,167|175,176|230,232|234,241|249,249|252,252|258,258|260,263|266,266|271,272|274,296 Q:0,3|5,23|28,34|38,38|41,49|52,57|60,61|63,63|66,66|68,69|73,73|78,79|81,82|84,103|105,105|108,124|126,140|143,156|158,166|168,174|177,229|233,233|242,248|250,251|253,257|259,259|264,265|267,270|273,273 TTBS?TTSHHHHHHHHHHHHHHTT????HHHHHTS???B??HHHHHHHTT??TTBTTS??TT?S??B?TT???S????SS?TT?EEEEEEESBHHHHHHHHHHT?S??HHHHHHHHHHHTGGGSB?SEEEEEEETTEEEEE??TTTBSBSEEEEETT?EEEEEBTTS?EEEEEEE??SSSEEEEEEEETTTTEEEEEEEEEEEETTEEEEEEEEEETTEEEEEEEEEEES???S????????HHHHTTT?TT?BBTTS?B????SS?TTTT??B??????????????????????- 1VPR|A PF10291.4_muHD_seed 32 406 !Q:0,0|22,34|47,48|52,70|89,89|94,103|109,115|118,120|124,124|131,131|133,133|137,149|157,167|178,178|191,191|195,195|198,199|201,206|219,219|222,236|243,243|247,250|252,252|256,256|262,262|265,265|272,275|287,289|291,299|302,302|310,312|314,314|317,318|323,323|325,327|331,340|348,348|351,373|376,376|386,386|388,401 Q:1,21|35,46|49,51|71,88|90,93|104,108|116,117|121,123|125,130|132,132|134,136|150,156|168,177|179,190|192,194|196,197|200,200|207,218|220,221|237,242|244,246|251,251|253,255|257,261|263,264|266,271|276,286|290,290|300,301|303,309|313,313|315,316|319,322|324,324|328,330|341,347|349,350|374,375|377,385|387,387|402,405 ?EEEEEEEEEEEEEEETTEEEE-------------EEEEEEEEEEEE??SSS????----?----------SEEEEEEETGGGEEEEEE?TTTE----------EEEET-------TE---EEE?TTTTBT?E-EEE-------------EEEEEES--------???SEEEEEEEEE?SSEEEEEEEEEE?TTS?TT??E------EEEEEEEEEEEB?SS--------------?EEEEEE-SSS--??B?SSS?EEEEE?SS?EEEETT???-EEEEEEEEESS???B--------?SS?EEEEEEE???S?SS?-TTTT?S???EEE----------EEEESSS?TT???-------------------?EE?EEEEEEEEE-E--------------EEEE 3G9H|A PF10294.4_Methyltransf_16_seed 15 203 !Q:0,0|4,4|12,12|15,15|17,17|19,22|39,50|54,54|59,59|66,66|69,69|79,85|87,87|94,94|97,97|112,114|116,116|125,126|130,137|139,142|150,151|168,169|172,172|174,175|182,184 Q:1,3|5,11|13,14|16,16|18,18|23,38|51,53|55,58|60,65|67,68|70,78|86,86|88,93|95,96|98,111|115,115|117,124|127,129|138,138|143,149|152,167|170,171|173,173|176,181|185,202 ?TTS?EEEEESB?TT-S?B????HHHHHHHHHHTSHHHH?-----------SSS?TTTT?EEEEES?TT?HHHHHHHTT-------T?EEEEEE?GG-GHHHHHHHHHHSGG---G?SSEEEEEE??TTS-??-????S?-?-SEEEEES??SSGGGTHHHHHHHHHH??TT?E--EEEEEE???STTHHHHHHHHHHHHTTT 2OZV|A PF10298.4_WhiA_N_seed 74 97 !Q:6,8|21,31|38,38|54,56|64,74|79,84|87,89|93,93|96,97 Q:0,5|9,20|32,37|39,53|57,63|75,78|85,86|90,92|94,95 HHHHHH---HHHHHHHHHEEE???--???---EEEEES?HHHHHHHHHHHHHTT-??EEEEEEE???????---?EEEE------EE???GGG-GG?- 3HYJ|A PF10320.4_7TM_GPCR_Srsx_seed 23 284 !Q:17,17|21,22|55,56|92,92|100,101|104,107|124,124|129,131|133,133|142,142|145,151|178,182|189,202|238,238|240,240|245,245|265,266 Q:0,16|18,20|23,54|57,91|93,99|102,103|108,123|125,128|132,132|134,141|143,144|152,177|183,188|203,237|239,239|241,244|246,264|267,283 HHHHHHHHHHHHHHHHH?GGG??HHHHHHHHHHHHHHHHHHTHHHHHHHHHHHSS??SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?HHHHHHH??HH----HHHHHHHHHHHHHHHH-HHHT???S-HHHHHHHH?TT???????HHHHHHHHHHHTHHHHHHHHHHHHHH-----HHHHHH??????????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-H?TTSS?HHHHHHHHHHHHHGGGHHH--HHGGGSHHHHHHHHHHH 4EJ4|A PF10323.4_7TM_GPCR_Srv_seed 25 316 !Q:17,18|26,30|61,64|68,68|75,77|107,108|110,110|113,116|119,121|139,143|151,151|159,160|162,164|197,202|204,229|263,264|271,273|275,275|280,281|302,302 Q:0,16|19,25|31,60|65,67|69,74|78,106|109,109|111,112|117,118|122,138|144,150|152,158|161,161|165,196|203,203|230,262|265,270|274,274|276,279|282,301|303,315 HHHHHHHHHHHHHHHHH--HHHHSTT---??SHHHHHHHHHHHHHHHHHHHTHHHHHHHHH----HTS?TTHHHH---HHHHHHHHHHHHHHHHHHHHHHHHHHHHH??S-SS????HH---HHHHHHHHHHHHHHHHH-----SGGGTTS?EEEETTE??S???GGGTHHHHHHHHHHTTHHHHHHHHHHHTTSTT?-----S??--------?????--------???SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--HTTTTS???S-HHHH--HHHHHHGGGGTHHHHHHHHH?HHHHHHHHHHHTT 1HZX|A PF10324.4_7TM_GPCR_Srw_seed 90 413 !Q:4,6|29,29|33,33|64,70|78,84|88,88|95,96|100,110|129,130|134,137|164,164|166,166|169,183|191,200|202,220|223,224|227,231|241,243|248,250|253,253|279,279|282,282|285,286|291,302|305,305|328,328|333,346|349,351|354,354|357,369|381,383 Q:0,3|7,28|30,32|34,63|71,77|85,87|89,94|97,99|111,128|131,133|138,163|165,165|167,168|184,190|201,201|221,222|225,226|232,240|244,247|251,252|254,278|280,281|283,284|287,290|303,304|306,327|329,332|347,348|352,353|355,356|370,380|384,412 HHHH---HHHHHHHHHHHHHHHHHHHGGG?SHH-HHHHHHHHHHHHHHHHHTHHHHHHHHTTTS?------TTHHHHH-------HHH-HHHHHH--HHH-----------HHHHHHHHHHHHHHHHHH??STT????HHHHHHHHHHHHHHHHHHHHHHHTTS-S?EE---------------EETTTTE----------E-------------------EE??SS---??TTTTHHHHH---HHHH---HH-TTHHHHHHHHHHHHHHHHHHHHHHH?TT?HH--HHHH------------HH-HHHHHHHHHHHHHHHHHHHHHH-HHHH--------------HH---HT?SS------??----?HHHHHHHHHHH---HTHHHHHHHHHTTTSHHHHHHHHHHHTTT 1HZX|A PF10328.4_7TM_GPCR_Srx_seed 80 328 !Q:20,21|25,25|45,48|51,51|63,65|68,69|85,85|104,104|108,112|119,125|134,138|152,152|161,162|164,165|174,175|178,178|182,182|188,191|217,218|222,222|229,230|248,248|265,266|270,285|302,303|312,314|325,325|328,328 Q:0,19|22,24|26,44|49,50|52,62|66,67|70,84|86,103|105,107|113,118|126,133|139,151|153,160|163,163|166,173|176,177|179,181|183,187|192,216|219,221|223,228|231,247|249,264|267,269|286,301|304,311|315,324|326,327 HHHHHHHHHHHHHHHHHHHH-?STT?STTHHHHHHHHHHHHHHHH----HH-STTHHHHHHHT---TS??SHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHTTS?TTT?????HHHHHH-------HHHHHHHH-----HHHHHSGGGGEEE?TTSSSEEE??S??SHHHHHHH--HH-HHH-HTTHH----HHHHHHHHHHHHHTTHHHHHHHTTT??TTH-HHHHHH--HHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHS?-GGG------------??--HHHHHHHHHHHHGGGS--HHHHHHHH?--HHHHHHHHHH?GG- 1HZX|A PF10340.4_DUF2424_seed 5 406 !Q:0,2|9,12|16,24|28,29|32,35|39,43|48,63|66,82|85,89|92,92|94,100|112,113|118,120|123,127|130,131|137,138|144,145|160,160|162,162|165,168|174,177|180,183|186,186|203,203|207,208|229,231|237,241|249,252|255,257|267,267|269,271|273,274|289,290|292,292|295,295|299,299|304,305|308,324|333,333|342,347|353,363|366,373|375,387|395,396|398,399 Q:3,8|13,15|25,27|30,31|36,38|44,47|64,65|83,84|90,91|93,93|101,111|114,117|121,122|128,129|132,136|139,143|146,159|161,161|163,164|169,173|178,179|184,185|187,202|204,206|209,228|232,236|242,248|253,254|258,266|268,268|272,272|275,288|291,291|293,294|296,298|300,303|306,307|325,332|334,341|348,352|364,365|374,374|388,394|397,397|400,405 ---HHHHHH----HHH---------HHS??TT????HHH-----HHHH----------------HH-----------------HH?????TT?E-------EEEEEETTEEE--EEEE?--TT?---?TT-?EEEEE??STTTS??HHHHHHHHHHHHHH-H-TS----EEEEE????TT----TS?TTHHHHHHHHHHHHHH-HHT??GEEEEEETHHHHHHHHHHHH---HHHTT?-???SEEEEES????TT???THHHHTTTT?S---S??TTHHHHHHHHHHTT--S?TT?TTT?GGGS??TT---------???-----EEEEEETT?TTHHHHHH------HHHHH-----------HT--------T-----------??EEEEEET--T??TTGGGG 3AIL|A PF10341.4_TPP1_seed 51 238 !Q:0,1|11,50|52,52|63,73|75,76|79,81|85,85|90,117|120,120|123,123|130,131|139,142|146,150|153,162|165,165|181,184|189,190|193,228|232,236 Q:2,10|51,51|53,62|74,74|77,78|82,84|86,89|118,119|121,122|124,129|132,138|143,145|151,152|163,164|166,180|185,188|191,192|229,231|237,237 ??HHHHHHSSS-------------------------------------???S?EEEEEEEEEE?????----??S??SS???TTS?EEEE----------------------------EE?SS?EEEEEE?-HHHHHTS?--?TTS----?SS?---------TT?TTEEEEEEEEEEEEE--??BTTB??EE------------------------------------EEE-----E 2I46|A PF10357.4_Kin17_mid_seed 30 158 !Q:0,10|14,14|37,37|50,50|54,57|60,75|79,79|101,103|106,113|120,121|138,157 Q:11,13|15,36|38,49|51,53|58,59|76,78|80,100|104,105|114,119|122,137 ????????--?GGG?HHHHHHHHHHHHHHHHHHHTSS?EEEHHHHHHHHT-TSS????GG----------------GSS?SSHHHHHHHHTTTTSEEEEEE---TT--------EEEEEE??SSHHHHHHHHHTGGGT?------------------- 2V1N|A PF10368.4_YkyA_seed 17 206 !Q:0,10|33,33|57,59|61,61|102,111|158,159|199,205 Q:11,32|34,56|60,60|62,101|112,157|160,198 -----------HHHHHHHHHHHHHHHHHHHTTH-HHHHHHHHHHHHHHHHHTTTTGG---G?SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSTT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??---?? 2AP3|A PF10369.4_ALS_ss_C_seed 160 81 !Q:10,12|14,15|30,30|40,40|48,48|60,60|62,62|71,73|78,78 Q:0,9|13,13|16,29|31,39|41,47|49,59|61,61|63,70|74,77|79,80 EEEEEEEEEE?-?T--HHHHHHHHHHHHTT?EEEEEETTE-EEEEEEE?HHHHHHHHHHS?G-GGEEEEEE???EEEE-ST 2F1F|A PF10370.4_DUF2437_seed 44 70 !Q:0,1|7,10|16,16|24,24|26,26|28,28|30,30|34,34|38,38|43,43|45,45|47,47|50,50|62,63|68,68 Q:2,6|11,15|17,23|25,25|27,27|29,29|31,33|35,37|39,42|44,44|46,46|48,49|51,61|64,67|69,69 ?-EEEEE----EETTE-EEEEEEE-S?T-T?GGG?EEE-EEEE?T-T-SS?EEEEEEEEGGG--SEEE?S 3RR6|A PF10371.4_EKR_seed 113 95 !Q:0,4|9,10|12,47|61,61|65,66|71,75|78,79|81,81|89,93|95,95 Q:5,8|11,11|48,60|62,64|67,70|76,77|80,80|82,88|94,94 ??--?GGGG--G??-------????--??---------?------???HHHHHTHHHHHTT?GGG??GGGS?----TT??B?TTGGGGT?????S- 2C3M|A PF10372.4_YojJ_seed 6 70 !Q:8,8|34,34|37,38 Q:0,7|9,33|35,36|39,69 HHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHTT?TT??GGGGHHHHHHHHHHHHHHHHHHHHHHHHTTT 2FB5|A PF10373.4_EST1_DNA_bind_seed 69 538 !Q:11,11|28,28|30,32|34,34|36,58|63,63|71,71|76,78|92,170|175,187|190,191|210,221|233,234|245,285|287,287|289,289|309,331|338,342|353,355|372,405|408,408|420,421|426,427|431,431|437,452|461,463|476,500|503,511|513,514|520,526|530,530 Q:0,10|12,27|29,29|33,33|35,35|59,62|64,70|72,75|79,91|171,174|188,189|192,209|222,232|235,244|286,286|288,288|290,308|332,337|343,352|356,371|406,407|409,419|422,425|428,430|432,436|453,460|464,475|501,502|512,512|515,519|527,529|531,537 HHHHHHHHHHH?TTBSHHHHHHHHHHHH-T---T?H-----------------------HHHH-HHHHHHH-SSSB??-HHHHHHHHHHHHH-------------------------------------------------------------------------------HTTS??------??--?SS??HHHHHHHHHHHHHHHHHT----------??GGGHHHHHHHH--HHHHHHHHHT-----------------------------------------T?S?HHHHHHHHHHHHHHHHHHS?----------------------GGGGTS?????HHHHHHHHHH---HHHHHHHHHHHHHHHH???-----------------------------??SS?SSSSSHHHHHH--HHHH--HTT?GGGGG---------------?HHHHTTTT---SHHHHHHHHGGG?-----------------------?BS??????-??S??HHHHH-------TTT?GGGHHHH 3ZHE|B PF10374.4_EST1_seed 27 207 !Q:22,39|44,44|47,48|78,178|201,201 Q:0,21|40,43|45,46|49,77|179,200|202,206 HHHTHHHHHHHHHTHHHHHHHH------------------HHHS?SS?-TTTTHHHHHHHHHHHHHHHHHHHHHHHHT????-????????------------------------------------------------------------------??????????????????????HHHHHHHHHHHHHHHHHHHHTT?HHHHH 1YA0|A PF10376.4_Mei5_seed 8 259 !Q:0,127|129,137|153,162|180,181|216,216|223,224|231,231|238,240|250,251|256,256 Q:128,128|138,152|163,179|182,215|217,222|225,230|232,237|241,249|252,255|257,258 ------------------------------------------------------------------------------------------------------------------------------??H---------HHHHHHHHHHHHHHH----------HHHHHHHHHHHHHHHHH??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT?EEEEEE??SSTTTT?EEEEEE???HHHHHHHTT??TTTS?EE 3VIQ|A PF10381.4_Autophagy_Cterm_seed 20 25 !Q:18,24 Q:0,17 GGGHHHHHHHHHTTTSTT??????? 2DYT|A PF10384.4_Scm3_seed 35 64 !Q:0,3|27,32|34,36|39,41|44,57|59,63 Q:4,26|33,33|37,38|42,43|58,58 ---?HHHHHHHHHHHHHHHHHHHHHTT?--???S???SS---SS??---?????????S????? 2L5A|A PF10385.4_RNA_pol_Rpb2_45_seed 149 111 !Q:4,8|11,23|27,29|37,37|45,45|48,48|52,54|56,66|70,70|74,77|79,79|82,83|86,86|90,91|93,100|104,105|110,110 Q:0,3|9,10|24,26|30,36|38,44|46,47|49,51|55,55|67,69|71,73|78,78|80,81|84,85|87,89|92,92|101,103|106,109 EEEE-----ET-------------TEE---EEEEEEE?HHHHHHS?EE?SSS--?B----------?SSS-SBS----S-SS??EE-BTT--B?---????TTT??EEES? 3AOH|C PF10386.4_DUF2441_seed 2 141 !Q:0,0|9,13|17,18|66,66|70,71|75,75|97,100|115,115|120,121|124,126|140,140 Q:1,8|14,16|19,65|67,69|72,74|76,96|101,114|116,119|122,123|127,139 ?HHHHHHHT?????TTS??HHHHHHHHEETTEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?TTS??TTS?EEEBSSHHHHHHHHHHHHHTT????EEEEEEEEEEEEEE?GGGS??SS???HHHHHHHHHHHHH? 2AUA|A PF10387.4_DUF2442_seed 153 99 !Q:11,13|22,25|27,27|32,32|37,37|40,40|43,44|49,58|61,61|74,81|96,97 Q:0,10|14,21|26,26|28,31|33,36|38,39|41,42|45,48|59,60|62,73|82,95|98,98 EEEEEEETTTT---EEEEEETT----S?EEEE?GGGS-TT?TT??HHHH----------TT?EEETTTTEEEET--------TTTEEEEHHHHHTT??S 2AUW|A PF10388.4_YkuI_C_seed 14 171 !Q:0,2|43,43|50,51|53,53|69,69|82,82|84,84|89,89|103,103|105,105|122,122|124,126|129,131|134,134|138,138|148,148|159,159|169,170 Q:3,42|44,49|52,52|54,68|70,81|83,83|85,88|90,102|104,104|106,121|123,123|127,128|132,133|135,137|139,147|149,158|160,168 ???TTTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHTT??S?HHHHHHHHHHHTTTT?SEEEEEETTSBB?S?EEEE-ETTEEEEEGGGTT?B?TTSTTHHHHHHHHHHH?S?--EE???EE?TTT?SEEEEEEEE?STTEEEEEEE?HHHHHTSSS?? 3BY9|A PF10389.4_CoatB_seed 6 46 !Q:0,0|45,46 Q:1,44 ?TTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?- 2IFO|A PF10390.4_ELL_seed 19 558 !Q:0,165|169,467|469,469|482,482|484,484|496,498|525,525|533,534|537,537|540,541|556,557 Q:166,168|468,468|470,481|483,483|485,495|499,524|526,532|535,536|538,539|542,555 ---??-----------------------------------------------------?????------------------------------------------------------------------------------------------------------?STT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S?HHHHHHHHHHHS?B?HHHHHHHHHHH???HHHHHHHHHHHHHHEEEETTTTEEEE?STHHHHS?-TT?TT??TTHHHHHHHHHHHH?? 2DOA|A PF10391.4_DNA_pol_lambd_f_seed 58 57 !Q:9,10|20,20|23,24|30,32|35,36|38,38|40,41 Q:0,8|11,19|21,22|25,29|33,34|37,37|39,39|42,56 HHHHHTSTT??HHHHHHHHH-TT??SHHHH---HT??T-T??HHHHHHHHTHHHHHS 8ICZ|A PF10393.4_Matrilin_ccoil_seed 14 47 !Q:0,2|6,6|9,9|46,47 Q:3,5|7,8|10,45 ???SSS?SS?TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?- 1AQ5|A PF10394.4_Hat1_N_seed 45 371 !Q:13,42|44,47|54,54|57,63|66,66|68,69|71,72|81,82|90,90|101,102|109,109|113,114|117,117|119,119|123,130|138,139|142,142|144,165|167,168|170,170|174,178|185,187|189,210|215,220|223,224|227,227|231,253|256,257|260,261|263,265|270,339|344,344|348,348|351,353 Q:0,12|43,43|48,53|55,56|64,65|67,67|70,70|73,80|83,89|91,100|103,108|110,112|115,116|118,118|120,122|131,137|140,141|143,143|166,166|169,169|171,173|179,184|188,188|211,214|221,222|225,226|228,230|254,255|258,259|262,262|266,269|340,343|345,347|349,350|354,370 EEEHHHHEEEEEE------------------------------S----SGGGGT?GG-------GE-E??S??HHHHTTTT--EEESEES?EEEEEEETTT??EEEEEE?SEE??TT-T-TSS????----HHHHHHT--TS?T----------------------T-?B?SHH-----HHHHHH---H----------------------TGGG-??-??SE--EE-EEE-----------------------EE??TT--S???EEEE----------------------------------------------------------------------EEEE?TTS-TT---HHHHHHHHHHHHHHHST 2P0W|A PF10396.4_TrmE_N_seed 270 219 !Q:0,0|5,5|7,8|12,12|14,14|16,16|23,27|38,40|43,46|48,54|56,74|76,78|84,86|88,89|92,96|100,119|123,123|125,125|130,130|133,141|147,147|154,155|166,166|172,185|187,201|204,205 Q:1,4|6,6|9,11|13,13|15,15|17,22|28,37|41,42|47,47|55,55|75,75|79,83|87,87|90,91|97,99|120,122|124,124|126,129|131,132|142,146|148,153|156,165|167,171|186,186|202,203|206,218 ?EEEE?S??BTT-B?S?EEEEEE-----STTHHHHHHH---HE----E?-?----S??-----???---------T---TEEEE---E--EE??---SSS---------??-------??EEE-E-EEEE?TT--------?SSSSS?EEEEEE??SSSHHHHHHH-HHHHT--------------T--------------?EE??TTHHHHHHHHTTS 3GEI|A PF10397.4_ADSL_C_seed 148 112 !Q:14,14|16,16|19,20|38,43|45,45|48,57|60,63|68,70|72,72|77,79|82,83|87,87|89,89|94,95|111,111 Q:0,13|15,15|17,18|21,37|44,44|46,47|58,59|64,67|71,71|73,76|80,81|84,86|88,88|90,93|96,110 TTGGGHHHHHHHHH-H-TT??HHHHHHHHHHHHHHHHT------S-SS?---------HH----HHHH---T?HHHH---TT??HHH-H-HHTT-?THHHHTTHHHHHHTT? 2PFM|A PF10398.4_DUF2443_seed 3 79 !Q:0,0|27,28|41,43|46,47|76,76 Q:1,26|29,40|44,45|48,75|77,78 ?HHHHHHHHHHHHHHHHHHHHHHHHHT??HHHHHHHHTTSS???TT??GGGHHHHHHHHHHHHHHHHHHHHHHGGG?ST 1ZKE|A PF10399.4_UCR_Fe-S_N_seed 49 41 !Q:0,9|39,40 Q:10,38 ??????????SHHHHHHHHHHHHHHHHHHHHHHHHHTTS?? 2FYN|C PF10400.4_Vir_act_alpha_C_seed 37 95 !Q:0,4|17,17|44,44|50,53|58,59|93,95 Q:5,16|18,43|45,49|54,57|60,92 ?????HHHHHHHGGGTS?HHHHHHHHHHHHHHHHHHHHHHHHHH-HHHSS?---GGGS-?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??- 1YG2|A PF10401.4_IRF-3_seed 43 239 !Q:2,2|13,14|16,16|21,22|25,25|30,32|35,37|45,46|48,58|65,68|71,79|93,93|96,96|105,105|112,112|116,116|125,126|128,132|135,137|139,140|143,145|157,180|190,190|193,199|207,207|210,211|213,213|215,215|219,219 Q:0,1|3,12|15,15|17,20|23,24|26,29|33,34|38,44|47,47|59,64|69,70|80,92|94,95|97,104|106,111|113,115|117,124|127,127|133,134|138,138|141,142|146,156|181,189|191,192|200,206|208,209|212,212|214,214|216,218|220,238 TT?EEEEEEETTS??E-EEEE??TT?EEEE?-?SS???GGGHHHH??T-----------TSEEEE????TT--??----?HHHHHHHHHHHTT?SS?EEEEEETT-EEEEEE?SSS?EEEESTTS??S?----SS??-B??BT-??EEEEEHHHHHH------------------------HHHHHHTTS?SS???-?-?EEEEESS?SS?-S-S?GGG?SEEEEEEEHHHHHHHHHHH 3DIT|A PF10403.4_BHD_1_seed 56 87 !Q:4,4|6,6|10,20|26,26|36,36|42,42|44,45|47,50|55,55|61,75 Q:0,3|5,5|7,9|21,25|27,35|37,41|43,43|46,46|51,54|56,60|76,86 HHHH?S?SSS-----------GGGTT?SSEEEGGGS?TTEEE?T--T????EEEE?TTSTT--------------?EEEEEEGGGEE 2QSH|A PF10404.4_BHD_2_seed 62 109 !Q:0,0|2,2|10,11|16,16|19,22|24,26|30,86|91,91|96,102|105,108 Q:1,1|3,9|12,15|17,18|23,23|27,29|87,90|92,95|103,104 ?B?HHHHHTT--TEEE?TT??-?S---EEE??-----------?????-???????------------------------------?EEEB?GGGE-------EE???? 2QSH|A PF10405.4_BHD_3_seed 34 98 !Q:0,3|7,7|10,10|17,17|25,31|40,50|54,55|66,71|75,75 Q:4,6|8,9|11,16|18,24|32,39|51,53|56,65|72,74|76,97 ????TTS?EE?SSGGGS?TTEEEEE------?TTHHHHHH-----------HHT??EEEEEEEEEE-----?STT?EEEEEEEEEEEGGGHHHHHHHH 2QSH|A PF10408.4_Ufd2P_core_seed 50 1116 !Q:6,7|11,22|30,35|37,38|41,41|44,45|78,78|83,84|95,96|100,100|107,132|134,135|140,143|165,174|176,176|183,183|187,220|224,226|230,238|241,242|246,247|262,262|264,307|351,358|391,391|394,394|417,427|431,432|436,436|438,440|442,448|451,453|455,457|460,460|462,517|526,549|568,570|579,584|589,589|591,591|606,606|609,609|611,613|629,631|633,633|635,638|643,650|655,655|659,663|681,683|685,688|690,690|712,712|718,718|727,802|805,805|821,821|837,838|844,896|900,951|982,983|986,986|992,992|1019,1023|1025,1025|1031,1034|1051,1060|1062,1062|1065,1067|1075,1075|1079,1080|1096,1096 Q:0,5|8,10|23,29|36,36|39,40|42,43|46,77|79,82|85,94|97,99|101,106|133,133|136,139|144,164|175,175|177,182|184,186|221,223|227,229|239,240|243,245|248,261|263,263|308,350|359,390|392,393|395,416|428,430|433,435|437,437|441,441|449,450|454,454|458,459|461,461|518,525|550,567|571,578|585,588|590,590|592,605|607,608|610,610|614,628|632,632|634,634|639,642|651,654|656,658|664,680|684,684|689,689|691,711|713,717|719,726|803,804|806,820|822,836|839,843|897,899|952,981|984,985|987,991|993,1018|1024,1024|1026,1030|1035,1050|1061,1061|1063,1064|1068,1074|1076,1078|1081,1095|1097,1115 THHHHT??TTS------------HHHHHHH------H--TT?TT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?HHHH--HHHHHHHHHH--HHT?GGGGSS--------------------------S??GGGS??--HHHHHHHHHHHHHHHGGGGST----------T?TTGGGS?TTT----------------------------------TSS?-?SSS??-------TT??BSS??HHHHHHHHHHTTTS?S?----------------------------------------???HHHHHHHHHHHHHHHTHHHHHHHHHTHHHHHHHHHHHHHHHTT?----???SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HT?HHHHHHHHHHHHHHHHHHHHHH-----------STT??TTS-S???S?------SS???S???SS?H--------------------------------------------------------HHHHHHTS?-----------------------TTGGGSBTHHHHHHHHHH---HHHTTSTT-----?SSTT?T-THHHHHHHHHHHHH?TT-S???HHHHHHHHHHHHHHH???S-S????TTHH--------HHHH?HHH-----HTTHHHHHHHHHHHGGG???S----S?TTSHHHHHHHHHHHHHHHHHH?HHHHH-HHHHHHHH---------------------------------------------------------------------------?HH-HHHHHHHHHHHHHTT-HHHHHHHHHHHHHHH--HHHTT????????--------------------------------------????--?TTH----------------------------------------------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--TT?GGGGS-STTTHHHHHHHHHHHHHHHHSHHHHS-?-??S?GGGGT--??HHHHHHHHHHHHHHHT----------T?HH---HHHHHHH?TTT??HHHHHHHHHHHTTSS?SSTTHHHHHHHHHHHHHHH 2QIZ|A PF10409.4_PTEN_C2_seed 61 343 !Q:0,3|13,18|21,34|36,40|44,48|50,60|73,88|91,93|96,96|100,112|126,126|129,129|131,132|140,140|143,146|149,153|156,156|159,163|174,306|320,320|324,324|327,327|331,331|334,334 Q:4,12|19,20|35,35|41,43|49,49|61,72|89,90|94,95|97,99|113,125|127,128|130,130|133,139|141,142|147,148|154,155|157,158|164,173|307,319|321,323|325,326|328,330|332,333|335,342 ????EEEEEEEEE------SS?-----------??S-----BTT-----B?---------?EEEEEEETTEEE----------------EE-??SS?SEE-------------ETTEEEEEEEEEE-EE-E--SEEEEEE-EE??--TT----?SS?EE-----EEEEEEEGGG??-------------------------------------------------------------------------------------------------------------------------??????????SEEEEEEGGGSTT-GGG?TT?SSS?TT?EEEEEEEE 3V0I|A PF10410.4_DnaB_bind_seed 185 71 !Q:11,12|14,18|20,21|23,24|37,37|45,48|65,65|67,67 Q:0,10|13,13|19,19|22,22|25,36|38,44|49,64|66,66|68,70 HHHHHHHHHGG--G-----S-?T--TSHHHHHHHHHH-HHHHHTT??-?HHHHHHHHHHHHHHHT?S?GGG 1DDE|A PF10411.4_DsbC_N_seed 144 86 !Q:2,3|8,13|16,18|20,22|24,25|30,30|32,34|38,38|45,46|49,51|53,58|67,68|72,75|78,79|81,81 Q:0,1|4,7|14,15|19,19|23,23|26,29|31,31|35,37|39,44|47,48|52,52|59,66|69,71|76,77|80,80|82,85 HH--HHHH------HT---T???E--EEEE?S---STT-EEEEEE--TT---E------EEEEETTS-?EEE?-??EE--E?SSSS 2IYJ|A PF10412.4_TrwB_AAD_bind_seed 37 468 !Q:0,1|8,10|17,17|22,23|43,50|52,52|68,79|82,84|88,88|94,98|103,104|118,120|122,123|147,147|151,152|154,156|168,168|186,186|194,194|214,231|238,238|241,249|255,255|280,281|283,291|294,298|305,305|310,310|312,312|322,322|335,335|344,344|347,347|356,357|362,365|368,368|378,378|381,383|390,421|426,428|433,433|440,442|447,451|455,455|459,460|466,467 Q:2,7|11,16|18,21|24,42|51,51|53,67|80,81|85,87|89,93|99,102|105,117|121,121|124,146|148,150|153,153|157,167|169,185|187,193|195,213|232,237|239,240|250,254|256,279|282,282|292,293|299,304|306,309|311,311|313,321|323,334|336,343|345,346|348,355|358,361|366,367|369,377|379,380|384,389|422,425|429,432|434,439|443,446|452,454|456,458|461,465 ??EETTEE?-?GGGGGG?EEEE??TTSSHHHHHHHHHHHHHHT--------T?EEEEEEETTHHHHHH??----------SS--?EEE?TTBTT?????GGGG??STTHHHHHHHHHS?--B?-SSHHHHHHHHHHHHHHHHHHHHH-HHT--T???HHHHHHHHHTS?HHHHHHHHTTSTHHHHT?SSHHHHH-HHHHHHHHHHHHTHHHHTS??------------????HHHHHH?TT------???EEEEE?GGGHHHHHHHHHHHHHHHHHHGGG--S??------?TT--??-EEEEES?GGGS?B?SSHHHHHHH?TTTTEEEEEEES?HHHHHHHH?HH-HHHHHHHT??EEEE????TT?HHHHHHHHH-HH?--EEEEEE???????????----??-----------????EEEE---EESS?HHHHHT-??TTEE-----EEE?SSS??EEEEE?? 1GKI|A PF10413.4_Rhodopsin_N_seed 17 36 !Q:0,0|4,4|7,7|12,13|17,20|25,26|31,31 Q:1,3|5,6|8,11|14,16|21,24|27,30|32,35 ?SEE?SS?EESS??TTS????TTTS??TTTS?HHHH 1HZX|A PF10414.4_CysG_dimeriser_seed 132 61 !Q:20,21|36,36|47,47 Q:0,19|22,35|37,46|48,60 TTHHHHHHHHHHHHHHHHHH??SHHHHHHHHHHHTT?HHHHHHHHTT?HHHHHHHHHHHHT 1PJQ|A PF10415.4_FumaraseC_C_seed 258 63 !Q:9,9|25,26|33,33|38,46|54,55|61,62 Q:0,8|10,24|27,32|34,37|47,53|56,60 GGGGGHHHH?HHHHHHHHHHHHHHT??HHHHHH-HHTS?-------?HHHHHHH??GGGSS?? 1FUQ|A PF10416.4_IBD_seed 94 159 !Q:0,0|3,3|6,6|12,12|22,37|58,58|61,64|78,80|84,84|94,95|99,103|113,113|115,136|141,142|149,149|153,153 Q:1,2|4,5|7,11|13,21|38,57|59,60|65,77|81,83|85,93|96,98|104,112|114,114|137,140|143,148|150,152|154,158 ?HH-HH-HHTTS?HHHHHHHHS???-------------SSGGGSHHHHHHHHHHHHTT?HH----HHHHHTEEESSSS?--EEE?HHHHHHHHT??HHH-----HHHHHHHTT?E----------------------EEEE--EETTEE-EEE?TTEET 1PP7|U PF10417.4_1-cysPrx_C_seed 86 56 !Q:8,8|10,11|14,14|17,19|21,30|33,34|36,39|44,45|47,48|54,55 Q:0,7|9,9|12,13|15,16|20,20|31,32|35,35|40,43|46,46|49,53 HHHHHHHH-S-?BB?TT?-?T----------TS??B---?SSTG--G--GHHHH?? 1X0R|A PF10418.4_DHODB_Fe-S_bind_seed 180 49 !Q:0,3|11,12|15,16|19,19|25,25|27,30|34,35|39,39 Q:4,10|13,14|17,18|20,24|26,26|31,33|36,38|40,48 ????SSSSSSS??SE--EE?SSTTS?E----EET--TTT?BEEBTTTTB 1EP2|B PF10419.4_TFIIIC_sub6_seed 25 36 !Q:4,4|10,10|19,19|26,27 Q:0,3|5,9|11,18|20,25|28,35 EEEE?TTSSS?EEEETTEE-EEEEEE??SSEEEEEE 4BJJ|B PF10420.4_IL12p40_C_seed 21 138 !Q:2,2|4,4|14,15|25,27|31,31|40,77|81,82|87,89|97,97|103,104|106,106|114,114|118,119|123,125|127,127 Q:0,1|3,3|5,13|16,24|28,30|32,39|78,80|83,86|90,96|98,102|105,105|107,113|115,117|120,122|126,126|128,137 SS?S?EEEBSSTTT--EEEEEEEES-??SSE-EEEEEEEE-------------------------------------?SSS??EEEE???EEEEEEE?SSSEE--E-EEEEEEE-ETT??SSS???S?EEEEEEEEET 3D87|B PF10421.4_OAS1_C_seed 49 207 !Q:2,5|21,23|43,43|64,69|71,71|73,76|92,95|98,99|111,113|120,120|123,129|132,133|152,152|166,166|168,169|191,191|195,195|197,206 Q:0,1|6,20|24,42|44,63|70,70|72,72|77,91|96,97|100,110|114,119|121,122|130,131|134,151|153,165|167,167|170,190|192,194|196,196 SS???-HHHHHHHHHHHHHSS--?TTTTGGGGHHHHHTTTTTS?HHHHHHHHHHHHHHHHHHHH------H?S-???HHHHHHHHHHHHHHH-???SS??HHHHHHHHHHH---HHTGGG?EE??----?SS??SSSHHHHHHHHHHTTSSS?EEEETTEEEEEET?S-?HHHHHHHHHHHHHHTTSGGGB?TTS?B?????????? 1PX5|A PF10422.4_LRS4_seed 5 408 !Q:17,27|32,41|49,407 Q:0,16|28,31|42,48 HHHHHHHHHHHHHHHHH-----------HHHH----------HHHHHHH?????--------------------??????????????-----------------------????????????????----------------------????????????----------------------????????????????----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3N7N|E PF10423.4_AMNp_N_seed 67 177 !Q:28,32|46,84|104,109|116,117|123,123|125,132|139,144|150,153|155,176 Q:0,27|33,45|85,103|110,115|118,122|124,124|133,138|145,149|154,154 TTTHHHHHHHHHHHHHHHHHHHHHHHTT?????HHHHHTTTTEEEE???????????----?????--?????????????????TTTTHHHHHHHHHHHHHHH??????EEEEEE??GGGTS?S????--??HHHHHH------HHTTS????S???????????-?????????? 1T8S|A PF10425.4_SdrG_C_C_seed 35 210 !Q:0,2|5,5|13,16|21,23|31,32|42,42|45,47|51,55|61,72|77,79|83,85|93,93|95,95|100,100|103,106|109,109|116,116|120,134|138,138|142,143|150,151|153,153|156,158|167,168|171,171|174,177|188,202 Q:3,4|6,12|17,20|24,30|33,41|43,44|48,50|56,60|73,76|80,82|86,92|94,94|96,99|101,102|107,108|110,115|117,119|135,137|139,141|144,149|152,152|154,155|159,166|169,170|172,173|178,187|203,209 ???EE?SSEEEEE----EEEE---EETTTTE--EEEEEEEEE?SS--?EEE-----EEEEE------------EEEE???TTS???EEEEEEE?S?GGGS?TT????TT?TTTEEE?GGG???-----------?EEE?TTS-?EEEEEE--E?SS?--EEEEEEEE??TT?SS---?EEEEEEEEEE???--???????--?EEEEEEE 1R19|A PF10426.4_zf-RAG1_seed 53 30 !Q:0,0|4,5|9,11|26,29 Q:1,3|6,8|12,25 ?EEE??STT???EEEHHHHHHHHHTS???? 1RMD|A PF10429.4_Mtr2_seed 7 209 !Q:0,1|6,13|27,40|48,56|59,61|71,71|73,78|90,92|106,107|122,168|185,186|189,189|200,208 Q:2,5|14,26|41,47|57,58|62,70|72,72|79,89|93,105|108,121|169,184|187,188|190,199 ??HHHH--------HHHHHHHHHHHHH------????-???HHHHTTB--------?SS???EEETTEEES?H------HHHHHHHHHHS???EEEEEEEEEEEET--TTTEEEEEEEEEEE?-??????????????????????-----??????????????????EEEEEEEEEEGGGGGT??TT?EEEEEEEEEE????????? 3NV0|B PF10430.4_Ig_Tie2_1_seed 4 99 !Q:0,2|7,7|9,9|13,13|16,16|18,18|25,25|28,29|32,34|39,39|46,53|57,57|69,69|72,74|76,77 Q:3,6|8,8|10,12|14,15|17,17|19,24|26,27|30,31|35,38|40,45|54,56|58,68|70,71|75,75|78,98 ???EEEE?S?SEE?SS?E-EEEEEE?SS??SS??-EEEE?TTTSSS????-???EEE?TTSSSEEEEEE?TT???S??EEEEEEEEETTEEEEEEEEEE 2GY5|A PF10431.4_ClpB_D2-small_seed 772 122 !Q:0,1|12,15|19,19|24,24|27,28|30,30|32,34|37,39|42,43|46,46|52,52|58,58|60,63|69,69|86,94|100,103|107,108|110,111|113,113|115,115|118,119 Q:2,11|16,18|20,23|25,26|29,29|31,31|35,36|40,41|44,45|47,51|53,57|59,59|64,68|70,85|95,99|104,106|109,109|112,112|114,114|116,117|120,121 ??HHHHHHHHHH----HHH-HHHH-HH--H-T---TT-?-EE--EE?HHHHH-HHHHH-H---?BTTTB-TSHHHHHHHHHTHHHH---------HHHHH----HTS--S?-T-T?EE--EE 3J3U|A PF10432.4_bact-PGI_C_seed 29 198 !Q:0,3|17,21|27,27|46,49|65,66|68,100|106,106|110,110|114,125|136,138|140,141|146,148|150,152|156,160|181,182|185,186|197,197 Q:4,16|22,26|28,45|50,64|67,67|101,105|107,109|111,113|126,135|139,139|142,145|149,149|153,155|161,180|183,184|187,196 ????HHHHHHHHHHHTT---??EEEEE-GGGHHHHHHHHHHHHHTT????EEEEETGGGGTHHHH??S?--------------------------------EEEEE?TTS?HHH------------HHHHHHHHHH---H??EEEE???S---HHH-----HHHHHHHHHHHHHHHHHHHT??SS??HHHHHHHHHT? 1X9H|A PF10433.4_MMS1_N_seed 38 824 !Q:0,3|12,15|25,56|69,75|78,80|83,84|86,86|89,90|95,95|98,99|115,116|118,137|139,139|142,144|149,149|151,176|184,184|186,191|193,193|196,196|205,206|209,209|218,237|248,248|251,252|255,256|259,264|269,270|272,289|292,292|298,298|301,301|306,315|317,322|330,331|334,344|346,346|350,350|357,385|391,391|400,400|411,417|430,432|434,434|441,441|445,455|465,466|473,522|525,526|530,530|539,542|544,545|551,551|558,579|586,587|589,589|592,592|599,823 Q:4,11|16,24|57,68|76,77|81,82|85,85|87,88|91,94|96,97|100,114|117,117|138,138|140,141|145,148|150,150|177,183|185,185|192,192|194,195|197,204|207,208|210,217|238,247|249,250|253,254|257,258|265,268|271,271|290,291|293,297|299,300|302,305|316,316|323,329|332,333|345,345|347,349|351,356|386,390|392,399|401,410|418,429|433,433|435,440|442,444|456,464|467,472|523,524|527,529|531,538|543,543|546,550|552,557|580,585|588,588|590,591|593,598 ?---EEEEEETT---?EEEEEEEEE--------------------------------ETTEEEEEEEEE-------EE???SS??B?SS??EEEE?TT??EEEEEEETTEEEEEE??T--------------------T?TT???EEEE?S------------------------??EEEEEEE?S------S?SS?EEEEEEEE--TT-EEEEEEEE--------------------EETTTTEEEE?SS??EE??TT?----?EEEE??T------------------TT?SEEEE?SS?EEEE----------E------TTEEEEE??TT-----------T-TTS?EEEEEE-----------------------------SSTTS?EEEEEESS?EEEEEEEEEE???????EEEEEEEEEEEE--?S?EEEEEE?STT-----------EEEEEESSS?-EEEEEE?-------------------------------------------------SS??SSS?SEEEEEEE????S??EEEEE?TTSSSS?---------------------EEEEEE??G-GG?EEEEEE??????---?????????-????????-----???????--??????????????????------------------------??????????--???????????????---?????????????????????????????---------???????????????????-??????????????---------?-??????------??-?????????---?? 3I8E|A PF10435.4_BetaGal_dom2_seed 38 206 !Q:4,4|6,8|10,10|16,16|18,18|28,34|38,39|51,53|58,58|66,66|76,78|85,86|97,97|99,99|118,118|120,120|128,128|131,131|138,143|145,145|148,149|155,156|159,159|172,172|175,176|179,179|187,191 Q:0,3|5,5|9,9|11,15|17,17|19,27|35,37|40,50|54,57|59,65|67,75|79,84|87,96|98,98|100,117|119,119|121,127|129,130|132,137|144,144|146,147|150,154|157,158|160,171|173,174|177,178|180,186|192,205 GTTS?B???B-SSSSB-S?SSEEEEEEE?------SSS-?EEEEEEESSTT???EEEE?EEEEETT-EEEEESSSS?-?EEEESS??EEEEEEEEET-T-EEEEEESSEEEEEEEETT-E-EEEEEEE?TT?EEEEEE------E?SS??EEEES??TT?EEEEETTEEEEE-EE??SS?EEEEETT-----EEEEEEEHHHHTTE 1TG7|A PF10436.4_BCDHK_Adom3_seed 57 429 !Q:0,2|11,13|18,32|36,42|66,66|92,93|95,203|206,207|211,230|239,239|251,252|255,255|268,269|273,294|300,306|323,326|334,357|361,422 Q:3,10|14,17|33,35|43,65|67,91|94,94|204,205|208,210|231,238|240,250|253,254|256,267|270,272|295,299|307,322|327,333|358,360|423,428 ???BHHHHHHH---HSSS?-------------?HHH-------HHHHHHHHHHHHHHHHHHHHTTS?HHHHHSHHHHHHHHHHHHHHHHHHT--T-------------------------------------------------------------------------------------------------------------TT??TTS--------------------TTTTHHHH-HHHHHHHHHHT--TH-HHHHHHHHHHHH--HHH-------------------???HHHHH-------HHHHHHHHHHHHHHHH----HHHHHHH------------------------HHH----------------??--???????-------------------------------???-BTTBEE 3TZ2|A PF10437.4_Lip_prot_lig_C_seed 94 94 !Q:0,4|15,15|38,40|42,42|44,45|54,54|57,57|72,74|77,77|82,82|84,85 Q:5,14|16,37|41,41|43,43|46,53|55,56|58,71|75,76|78,81|83,83|86,93 ?????SEEEEEEETT-EEEEEEEEEETTEEEEEEEEES???S-S?-THHHHHHH-TT?BSSHHHHHHHHTTS--?GG-GTST-T??HHHHHHHH 3R07|C PF10438.4_Cyc-maltodext_C_seed 32 117 !Q:4,8|18,49|51,51|62,62|66,66|81,82|90,92|96,96|99,102|107,107|110,110 Q:0,3|9,17|50,50|52,61|63,65|67,80|83,89|93,95|97,98|103,106|108,109|111,116 EEEE?-??-BTTEEEEEE--------------------------------E?SSEEEEEEEE?SSS?EEEEGGGGHHHHTT??EEEETTT-??EEE?SS----EEEE?TT?EEEEEE 3EDD|A PF10444.4_Nbl1_Borealin_N_seed 17 60 !Q:0,2|13,13|44,44|57,59 Q:3,12|14,43|45,56 ???TTHHHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHTS?HHHHTSBHHHHH??? 2QFA|B PF10447.4_EXOSC1_seed 32 145 !Q:0,2|5,5|15,15|28,82|86,98|100,100|105,105|107,107|117,117|120,121|124,125|130,132|135,135|144,145 Q:3,4|6,14|16,27|83,85|99,99|101,104|106,106|108,116|118,119|122,123|126,129|133,134|136,143 ???TT?EEEEEEEEE?SSEEEEEEEEEE?????????---------------------------???????????????????EEE??-----------S?TTTT?S?EEEEEGGGS?SS??SS??GGGT?-?TT?EEEEEEEE?- 2NN6|I PF10448.4_chaperone_DMP_seed 18 202 !Q:0,1|10,38|44,46|50,50|53,53|64,65|73,106|116,118|127,127|130,130|134,134|151,164|171,171|175,186 Q:2,9|39,43|47,49|51,52|54,63|66,72|107,115|119,126|128,129|131,133|135,150|165,170|172,174|187,201 ??EEEEEEES????????--------------???????EEEEE---EEE?SS?EEEEEEETTB??EEEEEEE??????-------????????????????-????SHHHHHHHH???EEEEEEES?TT?TTH-HHHHHHHHHHHHHTTS??????????????EEEEEE?GGG???--???????SSHHHHHHHHHHHHH 2Z5B|A PF10450.4_POC1_seed 3 284 !Q:0,33|37,47|61,61|67,67|71,72|76,119|121,122|135,137|141,142|157,157|162,163|166,167|171,171|177,177|180,180|187,191|194,195|197,197|215,217|225,225|232,232|234,235|252,253|257,259|283,283 Q:34,36|48,60|62,66|68,70|73,75|120,120|123,134|138,140|143,156|158,161|164,165|168,170|172,176|178,179|181,186|192,193|196,196|198,214|218,224|226,231|233,233|236,251|254,256|260,282 ??????????????????????????????????EEE???????????EEEEEEGGGGGGS?TTTTT?EEE??EEE????????????????????????????????????????????B??EEESSSEEEEEE???TTT??HHHHHHHHHHHHHH-HHTT??EE--EEE-EEETT?SS?EEEESS?????TT??B?SHHHHHHHHHHSSTTTT??-EEEEEEE?BSSTTS?B??HHHHHHHHHHHHHHHT??TTH---HHHHHHHHHHHSGGGHHHHTTSB? 4G4S|O PF10451.4_Stn1_seed 7 308 !Q:0,32|34,35|42,53|55,63|72,72|87,90|100,100|104,115|126,126|136,137|140,140|150,150|152,156|160,160|169,169|172,172|199,307 Q:33,33|36,41|54,54|64,71|73,86|91,99|101,103|116,125|127,135|138,139|141,149|151,151|157,159|161,168|170,171|173,198 ???????-----????????????---------B??HHHHTT-----------?B?????????EEETTEEE?EEEEEEEEEEEEEE----TTEEEEEEE?SSS?-----------EEEEEEEGGG?HHHHHHHTT??TT?EEEEEEEEE?S-----SSS?EEEEEEEE-EE?STHHHHHHHHHHHHHHHHHHHHHHHH????----------------------------------------------------------------------??--------------------------------- 3KF6|A PF10455.4_BAR_2_seed 10 441 !Q:0,39|61,62|64,64|71,78|82,84|91,104|106,121|123,124|129,159|169,171|175,217|288,324|328,328|332,377|385,388 Q:40,60|63,63|65,70|79,81|85,90|105,105|122,122|125,128|160,168|172,174|218,287|325,327|329,331|378,384|389,440 ?-???????-???????????--------------?????HHHHHHHHHHHHHHHHHHHHH--H-HHHHHH?----?--STT---THHHHT--------------T????????-???????S??HHHH-------------------------------HHHHHHHHH---HHH------------------------------------------?SSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHTT-------------------------------------TTS?HHH----------------------------------------------HHHHHHH----HHHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 2C08|A PF10456.4_BAR_3_WASP_bdg_seed 8 238 !Q:0,0|14,14|16,17|27,28|30,35|101,101|174,174|237,237 Q:1,13|15,15|18,26|29,29|36,100|102,173|175,236 ?SHHHHHHHHHHHT?S??GGGGGGTSB??S--????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHTTSSGGGS?HHHHHHHHHHHHHHHHHHHHHHHGGGTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGG? 3DYT|A PF10458.4_Val_tRNA-synt_C_seed 31 66 !Q:0,0|36,36|64,65 Q:1,35|37,63 ?HHHHHHHHHHHHHHHHHHHHHHHHHHTSTTHHHHS?TTHHHHHHHHHHHHHHHHHHHHHHHHH?? 1IVS|A PF10462.4_Peptidase_M66_seed 15 366 !Q:7,7|10,10|16,16|20,20|24,24|29,37|47,52|55,57|70,75|77,86|91,92|104,105|114,115|121,123|126,126|128,128|131,131|136,137|140,142|145,146|168,169|175,175|179,182|184,184|188,189|201,206|209,219|221,222|228,229|234,234|237,237|252,253|263,267|269,271|277,279|290,290|297,303|309,314|318,319|321,321|327,327|329,329|334,336|340,341|344,344|346,349 Q:0,6|8,9|11,15|17,19|21,23|25,28|38,46|53,54|58,69|76,76|87,90|93,103|106,113|116,120|124,125|127,127|129,130|132,135|138,139|143,144|147,167|170,174|176,178|183,183|185,187|190,200|207,208|220,220|223,227|230,233|235,236|238,251|254,262|268,268|272,276|280,289|291,296|304,308|315,317|320,320|322,326|328,328|330,333|337,339|342,343|345,345|350,365 GGGGEES?SS?EEEEE?GGG?STT?EEEE---------EETTEEEEE??--??EE???EEEEEEEEEEES------S????----??HHHH?-HHHHHHHHTTS??SEEEEEEB??EEESE---EE?T-TS?EEES??SS???SS??HHHHHIIIIIIHHHHHHHHHT??EEESS?STT????B?EEE--EEEEEEEETTE------EE-----------E??SEEET--TEEE?SS?SHHHHHHHHHHTTT??SSTTHHHHH-----B???TTSSS???EEETTTTEEE?SEEEEE??---??EEETT------EEE??B-TTEEE?B?TTTT???SBT--TB?S????HHHHHHHHHHHHTSBE 3UJZ|A PF10464.4_Peptidase_U40_seed 2 212 !Q:0,52|74,75|98,98|109,109|121,125|158,161|172,172|184,185|188,191|210,211 Q:53,73|76,97|99,108|110,120|126,157|162,171|173,183|186,187|192,209 ---------------------------------------??????????????EEEEEHHHHHHHHHHHHHHHT??HHHHHHHHHHHSEEETTEEEEE?SSSSBTTTTB?HHHHHHHHHTT?????HHHHTTSHHHHHHHHHHHHHHHHHHHHHHSTT????HHHHHHHHHH?HHHHHHHHHHS??SS????HHHHHHHHHHHHHHHSSS?? 4DQ5|A PF10466.4_Inhibitor_I34_seed 2 68 !Q:0,1|31,67 Q:2,30 ??HHHHHHHHHHHHHHHHHHHHHHHHHHHHT????????????????????????????????????? 1G0V|B PF10467.4_Inhibitor_I48_seed 2 149 !Q:0,1|15,15|17,18|20,21|26,27|33,33|47,47|53,53|57,57|63,63|67,67|70,70|75,75|78,79|82,82|84,84|89,91|97,97|100,100|109,110|112,112|133,134|136,140|148,148 Q:2,14|16,16|19,19|22,25|28,32|34,46|48,52|54,56|58,62|64,66|68,69|71,74|76,77|80,81|83,83|85,88|92,96|98,99|101,108|111,111|113,132|135,135|141,147 ??SEEEEEEEEESSS?S??S??EEEE??STTSB?EEEESSTTTGGGS?EEEEE?TTS?EEEEE?SSS?SS?EEEE?SS??TT?B?EEES???BEEEE?TT?SSEEEEEE??S?TTEEEEEEEETTEEEEEEEE??S?????EEEEEEE? 3H6R|A PF10468.4_Inhibitor_I68_seed 2 87 !Q:0,14|20,20|22,24|29,29|34,34|36,38|42,43|45,45|56,57|61,61|65,69|76,76|80,80|84,86 Q:15,19|21,21|25,28|30,33|35,35|39,41|44,44|46,55|58,60|62,64|70,75|77,79|81,83 -------------??HHHHT?B???TTTS?SSSB?S???SSS??B?TTTTSSGGGT??EEE?TTS?????TTTGGG?STT?EEE??? 2K2X|A PF10469.4_AKAP7_NLS_seed 50 413 !Q:0,1|8,11|14,14|28,95|98,98|102,103|108,109|112,113|121,123|127,127|134,138|147,147|152,174|179,184|186,187|193,193|201,217|223,224|227,228|232,235|245,248|254,254|260,261|263,264|267,316|325,351|359,359|362,366|376,376|383,386|394,394|397,399|403,405|412,412 Q:2,7|12,13|15,27|96,97|99,101|104,107|110,111|114,120|124,126|128,133|139,146|148,151|175,178|185,185|188,192|194,200|218,222|225,226|229,231|236,244|249,253|255,259|262,262|265,266|317,324|352,358|360,361|367,375|377,382|387,393|395,396|400,402|406,411 ??EEEEEE?-??HH-HHHHHHHHHHHHH--------------------------------------------------------------------HH?GGG--GGGB??TT??EEEEEEE???SHH-HHHHHH-----HHHHHHHH-HHHH-----------------------HTTT------S??EEEEE-EEEEETT-----------------TEEEE--EE??SHH----HHHHHHHHH----HHHHH-HHTTT??B??SS??---------------------------------------------???EEEEEGGG--------------------------?HHHHHTT?SS?---?GGGGGGGTT?EEEEEE?--?EEEEEES-SS???TTS???EEEEEE? 2VFK|A PF10470.4_AKAP7_RIRII_bdg_seed 3 61 !Q:0,0|5,7|24,60 Q:1,4|8,23 ?SSSS???STTHHHHHHHHHHHHH????????????????????????????????????? 3J4R|A PF10471.4_APC_CDC26_seed 42 92 !Q:0,12|15,15|22,91 Q:13,14|16,21 ?-???????????HH-HHHHHH??????????????????---------------------------????????????????????????? 3HYM|A PF10480.4_ICAP-1_inte_bdg_seed 2 200 !Q:0,60|70,84|101,101|104,105|107,107|114,114|122,129|137,138|145,146|148,151|153,153|158,167|194,199 Q:61,69|85,100|102,103|106,106|108,113|115,121|130,136|139,144|147,147|152,152|154,157|168,193 ---------------------------?????----------------?????????????EEEEEEEEE???????????????STTHHHHHHHHHHTSS?SS??S?EEEEEE?SSEEEEE????????EEEETTT??EEEEEB??S????B?EEEE??????????EEEEEESSSHHHHHHHHHHHHHHHHH?????? 4JIF|A PF10483.4_Elong_Iki1_seed 22 386 !Q:8,8|10,12|24,24|37,39|44,47|55,56|58,61|64,64|72,84|87,87|99,117|124,124|129,129|132,138|148,150|153,159|171,180|184,193|202,202|211,213|216,217|229,231|234,236|238,238|240,256|266,266|270,270|288,385 Q:0,7|9,9|13,23|25,36|40,43|48,54|57,57|62,63|65,71|85,86|88,98|118,123|125,128|130,131|139,147|151,152|160,170|181,183|194,201|203,210|214,215|218,228|232,233|237,237|239,239|257,265|267,269|271,287 HHHHHHTT?S-??SEEEEEEBTTB?SHHHHHHHHHHH---HHTS????EEEEESS??S?--?TT?SEEEETT-------------SS?HHHHHHHHHHT------??????????--?EEEEES?GGGS?GG-------GHHHHHHHH?-?TT-------EEEEEEEETTS??????????TTB------????HHHHHHHH?SEEEEEEE???SS??HHHHHHHHHTT???SS--?S?S-----------------EEEEEEEEE?TTS?EEEEEEEEETTTTEEEE????--------???-------------------????????????????????????????????-------------------------------- 4EJS|B PF10502.4_Peptidase_S26_seed 32 163 !Q:0,30|33,33|39,39|43,45|49,67|73,73|76,77|85,85|91,92|96,97|102,102|108,108|112,115|118,119|127,127|133,134|139,140|142,143|145,146|151,158|161,162 Q:31,32|34,38|40,42|46,48|68,72|74,75|78,84|86,90|93,95|98,101|103,107|109,111|116,117|120,126|128,132|135,138|141,141|144,144|147,150|159,160 ?????????????????????--------??TT?EEEEE?TTT?-?EEE-------------------EEEEE?TT??EEEETTE-EEETT--EEE??TTTT-TTGGT?TTT?--?SS??TTEEEEE?SSGGG??SHHH--H??E--EGGG?------?EE?? 1KN9|A PF10503.4_Esterase_phd_seed 2 226 !Q:6,8|10,11|14,14|16,16|18,20|27,28|31,31|36,36|56,57|63,65|68,69|76,76|79,79|84,84|98,98|123,123|127,127|131,135|140,143|145,160|170,176|185,185|189,189|205,206|208,217|223,223 Q:0,5|9,9|12,13|15,15|17,17|21,26|29,30|32,35|37,55|58,62|66,67|70,75|77,78|80,83|85,97|99,122|124,126|128,130|136,139|144,144|161,169|177,184|186,188|190,204|207,207|218,222|224,225 EEEEEE???S??TT-S?E---EEEEEE??GG?SSSS?HHSSTTTGGGGSHHHHTTS??EEEEE???TT??SBSGGG?SS?TTSB?HHHHHHHHHHHHS?EEEEEEEEEEETHHHHHHHHHHHH?TTT?SEE-----EEES????G----------------GGTTGGGGS------?EEEEEETT?SSS?THHHHHHHHHHHHTT??E----------EEEEE?TT 3FCX|A PF10509.4_GalKase_gal_bdg_seed 183 62 !Q:8,11|14,17|19,20|22,22|34,34|37,37|42,42|57,57 Q:0,7|12,13|18,18|21,21|23,33|35,36|38,41|43,56|58,61 HHHHHHHH----SS?--?S--E-EEEEEEEEEEE?TT?GGGT?EEEEEEEEEEEEEE-EEEE 2DEJ|A PF10512.4_Borealin_seed 9 133 !Q:0,76|78,78|81,83|88,91|93,95|101,102|110,110|132,132 Q:77,77|79,80|84,87|92,92|96,100|103,109|111,131 ------------??----------------------------------------???????????????-???---?S?EE???SSSS----S???EETTT??HHHHHTS?HHHHHHHHHHHHHHHHHHHHS? 2KDD|A PF10515.4_APP_amyloid_seed 9 60 !Q:10,10|13,59 Q:0,9|11,12 HHHHHHHHHT-SS???????????????----???---?????????????????????? 2YT0|A PF10518.4_TAT_signal_seed 64 26 !Q:0,2|20,23 Q:3,19|24,25 ???SHHHHHHHHHHHHHHHH????SS 2PQ4|B PF10522.4_RII_binding_1_seed 14 18 !Q:0,0 Q:1,17 ?HHHHHHHHHHHHHHHHT 2DRN|C PF10523.4_BEN_seed 70 105 !Q:12,12|20,20|24,27|31,42|46,50|53,54|70,72|75,85|93,94 Q:0,11|13,19|21,23|28,30|43,45|51,52|55,69|73,74|86,92|95,104 HHHHHHHHHHHS?HHHHHHE-ESS????GGG------------TTS?????EE??HHHHHHHHHHHHHHH???HH-----------HHHHHHH--HHHHHHHHHH 4IX7|A PF10528.4_PA14_2_seed 8 138 !Q:10,11|15,15|23,24|51,53|55,55|62,69|73,73|83,83|86,86|97,97|100,100|112,112|114,115|117,125|132,136 Q:0,9|12,14|16,22|25,50|54,54|56,61|70,72|74,82|84,85|87,96|98,99|101,111|113,113|116,116|126,131|137,137 SEEEEEEEEE??SSS-EEEEEEE--EEESEEEEEESBTTTBBTTBHHHHTT???S?SEEEET--------TSS?SEEEEEEEE?TT?BEEEEEEEEE?SS?EEEEEEEEETT?S??B??------?TTTEEE?-???S 4AI2|A PF10531.4_SLBB_seed 139 74 !Q:7,7|11,16|24,25|27,27|36,37|40,41|45,46|48,54|56,57|60,63|65,65|71,72 Q:0,6|8,10|17,23|26,26|28,35|38,39|42,44|47,47|55,55|58,59|64,64|66,70|73,73 EEEEESS-BSS-----?EEEEEET--T?BHHHHHHT--TT??BSS-?E-------E--EE----E?SSSSS??E 3I9V|1 PF10540.4_Membr_traf_MHD_seed 16 206 !Q:22,22|32,32|49,49|51,93|96,96|100,118|138,143|148,174|181,181|194,205 Q:0,21|23,31|33,48|50,50|94,95|97,99|119,137|144,147|175,180|182,193 HHHHHHHHHHHHHHHHHHHHHS?HHHHHHHHH-HHHHHHHHHHHHHTTS?G-------------------------------------------GG?SSS?-?-----???????????TTHHHHHHHHHHHHHHHHG------GGTS??-------------------------HHHHHT?HHHHHHHHHHHH???????????? 3SWH|A PF10541.4_KASH_seed 20 81 !Q:0,42|45,46|54,54|60,65|68,80 Q:43,44|47,53|55,59|66,67 ---------------------------???-----????????TT??TTTTSSS?EEEES------SS???---------? 4DXS|B PF10550.4_Toxin_36_seed 3 15 !Q:0,0|12,12 Q:1,11|13,14 ?HHHHHHHHHHH-HH 1ONT|A PF10555.4_MraY_sig1_seed 64 13 !Q:0,3 Q:4,12 ????HHHHHHHHH 4J72|A PF10557.4_Cullin_Nedd8_seed 109 72 !Q:1,3|20,20|36,36|38,40|42,45|65,66|69,69 Q:0,0|4,19|21,35|37,37|41,41|46,64|67,68|70,71 S???TTTHHHHHHHHHHHHH?EEEHHHHHHHHHHHT?S---S????HHHHHHHHHHHHHTTSEEE?-SS?SS 3DPL|C PF10559.4_Plug_translocon_seed 68 40 !Q:9,11|14,17|22,22|24,26|34,35|38,38 Q:0,8|12,13|18,21|23,23|27,33|36,37|39,39 HHHHHHHHS???SS----STTT?S???HHHHHHH-?SS?S 3KCR|A PF10563.4_CdCA1_seed 18 289 !Q:1,1|12,17|21,21|24,25|32,35|37,37|40,45|47,86|88,88|101,102|116,132|144,145|148,149|152,152|155,158|173,192|195,195|208,208|210,212|217,217|219,224|229,229|235,238|241,261|263,264|277,278 Q:0,0|2,11|18,20|22,23|26,31|36,36|38,39|46,46|87,87|89,100|103,115|133,143|146,147|150,151|153,154|159,172|193,194|196,207|209,209|213,216|218,218|225,228|230,234|239,240|262,262|265,276|279,288 T?EEEEEESGGG------GGG?EE??TTSEEB????S?BS?--???S??--------------------------------------B?TTTTHHHHHHHT??SHHHHHHHHHHHH-----------------HTTSEEEEEES??SS--SS?SH----HHHHHHTTTTGGGT??----------------??SS?HHHHHHHHHHTT?E---EEEB?S??????EEEE?STTEE????TT---------------------S??EEEEHHHHHHTT??HHHHHHHHHH 3BOE|A PF10564.4_MAR_sialic_bdg_seed 17 133 !Q:5,5|17,17|21,23|26,29|37,38|42,43|45,45|59,60|63,63|69,69|73,73|77,78|84,84|88,89|93,93|95,97|111,130|132,132 Q:0,4|6,16|18,20|24,25|30,36|39,41|44,44|46,58|61,62|64,68|70,72|74,76|79,83|85,87|90,92|94,94|98,110|131,131 HHHHH-HHHHHHHHHTT?GGG???GG----GEEEEEE??STT??S?EEEEEEGGGEESS??SS?EEEEE?TTS?EEE--EEEEE?TTT??EEE?H---HHHHHHHHHHHHH--------------------H? 2LBO|A PF10566.4_Glyco_hydro_97_seed 173 391 !Q:3,3|6,9|16,16|28,28|33,33|35,37|41,42|47,47|49,49|51,51|54,61|77,78|83,89|91,91|98,98|100,105|108,109|112,114|117,118|120,120|123,128|141,143|151,151|158,166|171,171|173,173|192,193|196,196|200,210|212,213|235,235|242,242|244,247|253,253|260,261|263,264|268,271|273,277|281,283|299,299|301,306|309,309|314,324|326,326|329,332|334,334|337,340|352,353|358,361|363,363|368,371|375,379|389,390 Q:0,2|4,5|10,15|17,27|29,32|34,34|38,40|43,46|48,48|50,50|52,53|62,76|79,82|90,90|92,97|99,99|106,107|110,111|115,116|119,119|121,122|129,140|144,150|152,157|167,170|172,172|174,191|194,195|197,199|211,211|214,234|236,241|243,243|248,252|254,259|262,262|265,267|272,272|278,280|284,298|300,300|307,308|310,313|325,325|327,328|333,333|335,336|341,351|354,357|362,362|364,367|372,374|380,388 TGG-GT??-?EEEEEE-THHHHHTSSBS?SBSS?S???TTT??GGGS?B?S?BS---?---?HHHHHHHHHHHHHTT??EEEE?------S?BTTGGG?S------SS??SS???SS-?B?TT----??HHHHHHHHHHTT--?EEEEEEE?TTBHHH---------HHHH-H-HHHHHHHHHTTEEEEEEE??SS?BST-----------T??TTSHHHHHHHHHHHHHHHHTT?EEEETT-S????SGGGT?TTEEEE??S??GGG----G-----GTT???TTGGGTGGGTTTTTS?B??????SS?BGGG-----------T?TT-???B?SS?---HHHHHHHHHHS??SEEE?--?S?HHHH----HTS-----HHHHHHHHH?? 2JKP|A PF10569.4_Thiol-ester_cl_seed 83 32 !Q:5,9|29,29 Q:0,4|10,28|30,31 TGGGG?????SSTTTTHHHHHHHHHHHHH-HH 4FXG|B PF10576.4_EndIII_4Fe-2S_seed 505 25 !Q:1,1|4,4|6,7|9,12|15,15|19,20|23,24 Q:0,0|2,3|5,5|8,8|13,14|16,18|21,22 S?SS-S??G----GG?TTS--TT-? 1MUN|A PF10582.4_Connexin_CCC_seed 76 76 !Q:17,18|24,26|30,32|36,36|41,41|60,62 Q:0,16|19,23|27,29|33,35|37,40|42,59|63,75 HHHHHHHHHHHTTTSSS??SEEEE?-?TTS---SSS-EEEE?SSHHHHHHHHHHHHHHHH---HHHHHHHHHHHHH 3IZ1|A PF10584.4_Proteasome_A_N_seed 74 23 !Q:7,8|12,13 Q:0,6|9,11|14,22 TTTTSSS??TTS??HHHHHHHHH 3TDD|A PF10585.4_UBA_e1_thiolCys_seed 65 51 !Q:3,4|9,22|29,31|42,42 Q:0,2|5,8|23,28|32,41|43,50 TTB??GGGS??????--?---??HHHHHH???SHHHHHHHHH-HHHHHHHT 4II2|A PF10588.4_NADH-G_4Fe-4S_3_seed 191 46 !Q:11,18|22,22|24,24|29,29|39,39|41,46 Q:0,10|19,21|23,23|25,28|30,38|40,40 HHHHHHHHHTS?----???TTT?T-TGGG?HHHHHHHHH?S?????- 3I9V|3 PF10589.4_NADH_4Fe-4S_seed 299 83 !Q:2,2|10,10|13,15|19,20|22,23|41,41|43,43|46,48|50,78 Q:0,1|3,9|11,12|16,18|21,21|24,40|42,42|44,45|49,49|79,82 HH-HHHHHHH-HH---HHH??S??HHHHTTTTTHHHHHHHH-H-TT---T--??----?--------------------HHHH 3I9V|1 PF10590.4_PNPOx_C_seed 243 112 !Q:15,16|20,21|27,39|41,48|50,88|93,104|110,111 Q:0,14|17,19|22,26|40,40|49,49|89,92|105,109 EEEEEEEEEEEEEEE??TTS??EEEEE-------------E-?------S---------------------------------------STTS-?---------?EEEEE?? 1CI0|A PF10591.4_SPARC_Ca_bdg_seed 28 143 !Q:0,4|30,30|34,34|38,38|51,51|55,58|60,62|89,90|93,93|98,98|110,112|127,127|130,130|133,133 Q:5,29|31,33|35,37|39,50|52,54|59,59|63,88|91,92|94,97|99,109|113,126|128,129|131,132|134,142 ?????HHHHHHHHHHHHHHHHHHHHHHHHH?STT-SSS?HHHHHHHHHHHT?TTS???-S???HHHHHHHHHHTTHHHHHHHHHHHHHH??SS?SSEE?TTTTGGGGSTT---STTGGGHHHHHHHH?TT?SS?EEHHHHHHH 1YX7|A PF10596.4_U6-snRNA_bdg_seed 11 192 !Q:5,5|8,9|11,11|14,15|20,27|55,55|58,97|99,104|119,128|132,133|135,136|139,139|144,144|147,147|149,150|158,160|182,184 Q:0,4|6,7|10,10|12,13|16,19|28,54|56,57|98,98|105,118|129,131|134,134|137,138|140,143|145,146|148,148|151,157|161,181|185,191 THHHH?SS??S?TT??HHHH?????--?HHHHHHHHHHTTHHHHHHTTSSTGGGT?SS????????-------------????????-??????????S??????HHHHHHHTHHHHSS----------TTT??S??EE?TTSS?EE?S??TTHHHHH---HHHTTTTHHHHHHHHHHHHHH---HHHHTTT 3ZEF|B PF10597.4_U5_2-snRNA_bdg_seed 20 138 !Q:0,2|22,22|26,26|44,44|46,48|74,74|97,97|100,101|103,105|112,112|118,121|123,123|125,127|129,130|135,135 Q:3,21|23,25|27,43|45,45|49,73|75,96|98,99|102,102|106,111|113,117|122,122|124,124|128,128|131,134|136,137 ???SSEEEEEETTTTEEEEEEE-EEE?HHHHHHHHHHHHHHHHS?S???HHHHHHHHHHHHHHHHHHHTHHHHT?HHHHHHHHHHHHHHHHHHHHHH?SS??S???HHHHHS?GGGTS????B?S??-B??GGGG?EE 3ZEF|B PF10598.4_RRM_4_seed 25 96 !Q:2,3|16,16|33,33|36,36|40,41|44,45|77,80|84,86|89,90|96,96 Q:0,1|4,15|17,32|34,35|37,39|42,43|46,76|81,83|87,88|91,95 TT??HHHHHHHHHHHB?HHHHHHHHHHHSSEEE?SS?EEE??SS??TTSTTHHHHHHHHHHHHHHHHHHHHHHHHHH?--?SSS???TT??SSHHH- 3ZEF|B PF10602.4_RPN7_seed 63 254 !Q:0,1|4,4|9,10|12,14|30,32|34,35|38,39|50,51|62,62|69,71|89,89|107,151|158,187|197,197|201,201|219,226|246,246 Q:2,3|5,8|11,11|15,29|33,33|36,37|40,49|52,61|63,68|72,88|90,106|152,157|188,196|198,200|202,218|227,245|247,253 ??SS?SSSS??S???HHHHHHHHHHHHHHT???S??SS??HHHHHHHHHH??SSSHHHHHHH-HHHHHT???SSHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHHTT--???----------------------------------------SHHHHH------------------------------HHHHTTTTT?SSS?HHHHHHHHHHHHHHHTS------??HHHHHHHHHHHHHHHHHTT?HHHHHHT 4BGR|R PF10604.4_Polyketide_cyc2_seed 179 343 !Q:0,1|7,12|14,17|21,21|23,23|34,36|38,39|44,49|51,54|56,62|64,65|67,72|74,75|77,82|84,84|86,88|91,91|96,117|119,123|128,128|132,142|146,157|165,166|168,171|173,173|175,177|187,191|194,200|206,208|211,212|216,216|222,224|227,228|230,236|238,242|245,246|249,251|255,260|264,267|269,286|289,300|305,312|315,318|325,328 Q:2,6|13,13|18,20|22,22|24,33|37,37|40,43|50,50|55,55|63,63|66,66|73,73|76,76|83,83|85,85|89,90|92,95|118,118|124,127|129,131|143,145|158,164|167,167|172,172|174,174|178,186|192,193|201,205|209,210|213,215|217,221|225,226|229,229|237,237|243,244|247,248|252,254|261,263|268,268|287,288|301,304|313,314|319,324|329,342 ??EEEEE------E----EES-S?HHHHHHHHTT---S--GGGG------G----T------?T--T??---?E--E------E-E---SS?TTST----------------------T?----EEEE-SSS-----------SSS?-----------EEEEEEE--E----E-T---TTTEEEEEE-----EE------?SSSEE---EE--EEE-EEEEE---SS--S-------S?----EE--EE---EEE------EEE----E-----------------?HH------------HHHH--------HH----HHTTTT----HHHHHHHHHHHHTT 3NJ1|A PF10609.4_ParA_seed 250 140 !Q:7,8|16,16|24,49|51,57|61,61|65,65|69,80|92,93|98,98|108,114|118,118|121,121|123,129|133,133|136,137 Q:0,6|9,15|17,23|50,50|58,60|62,64|66,68|81,91|94,97|99,107|115,117|119,120|122,122|130,132|134,135|138,139 EEEEEEE??SBSSSHH-HHHHHHH----------?--------------?S-------EEE-EEE?GGG?----------?HHHHHHHHHHH--HHTT?EEEEEEEES------?EEE?TT-T-----??EEE?TT--TT 3KB1|A PF10610.4_Tafi-CsgC_seed 2 106 !Q:0,7|28,28|31,31|44,44|47,47|60,60|67,69|74,75|78,78|88,88|92,92|99,105 Q:8,27|29,30|32,43|45,46|48,59|61,66|70,73|76,77|79,87|89,91|93,98 ------??EEEEEEEEETTEEEEEEEEE?SS?EEEEEEEEEEEE?SS?EEEEEEEEEEEE?SSSEEE???EEEE??TT?EEEEEEEEE?SSS?EEEEEE??????? 2XSK|A PF10613.4_Lig_chan-Glu_bd_seed 82 89 !Q:4,4|6,12|15,20|25,25|42,42|44,45|51,52|55,61|63,63|65,66|69,78|80,80 Q:0,3|5,5|13,14|21,24|26,41|43,43|46,50|53,54|62,62|64,64|67,68|79,79|81,88 TTBE-E???----SS??---?GGGG-EESHHHHHHHHHHHHH-T??EEEEE?-TT?--????B?S--SS---------?B?HHHHHHHT 2ZNU|A PF10615.4_DUF2470_seed 50 121 !Q:0,2|8,10|23,23|33,33|36,44|46,48|50,58|64,64|73,85|88,88|95,95|98,107 Q:3,7|11,22|24,32|34,35|45,45|49,49|59,63|65,72|86,87|89,94|96,97|108,120 ???TTTTH---HHHHHHHHHHHH?HHHHHHHHH-HH??-----??S---S??-------EEEEE?SSEEEEEE-------------TT-EEEEEE?SS?-------??SHHHHHHHHHHHH 3SWJ|A PF10633.4_NPCBM_assoc_seed 29 90 !Q:1,1|4,4|14,15|17,17|20,20|24,24|30,32|37,41|45,45|48,52|54,54|57,57|67,68|71,73|76,79|88,89 Q:0,0|2,3|5,13|16,16|18,19|21,23|25,29|33,36|42,44|46,47|53,53|55,56|58,66|69,70|74,75|80,87 E?TT?EEEEEEEEE??S-SS?BSS?EEEEE?-?TTSE-----EEE-EE?---?B?TT?EEEEEEEEE??TT???EE----EEEEEEEE-? 1W8N|A PF10634.4_Iron_transport_seed 30 193 !Q:0,4|10,12|17,18|30,32|36,38|40,43|45,46|50,50|61,61|63,64|66,66|70,71|74,76|78,79|81,81|93,95|101,101|104,104|118,128|141,141|145,150|153,153|157,157|162,180|186,186|191,192 Q:5,9|13,16|19,29|33,35|39,39|44,44|47,49|51,60|62,62|65,65|67,69|72,73|77,77|80,80|82,92|96,100|102,103|105,117|129,140|142,144|151,152|154,156|158,161|181,185|187,190 ?????EEEEE---EEEE--TTEEEEEEEES???EES?-?S----S??GGG?SEEEEEEEEE?T--T?SSS??TT-?-B??S?EEEEEEEETTT??-EEEEE?EE-EEETTEEEEEEEE-??-------?SSEEEEEEEEEE?GGG------GT?EEB?STTT??---------??--????EEEEE-EEEE?? 3LZP|A PF10635.4_DisA-linker_seed 39 150 !Q:1,2|39,40|87,87|101,105|108,110|126,128|138,140|142,142|149,149 Q:0,0|3,38|41,86|88,100|106,107|111,125|129,137|141,141|143,148 E??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??BHHHHHHHHHHHHHHHHHHHHHHHHHHHTGGGGHHHHHHHHHHHTT-HHHHHHHHHHHHS-----SS???HHHHHHHHHHHHTTS???HHHHHHHTT???S?GGGGGG? 3C1Y|A PF10636.4_hemP_seed 56 39 !Q:10,10|29,29|33,33|38,38 Q:0,9|11,28|30,32|34,37 TEEEHHHHTT-SSSEEEEEETTEEEEEEE?TTS?EEEE? 2JRA|A PF10637.4_Ofd1_CTDD_seed 39 619 !Q:10,10|37,37|39,39|57,58|60,63|68,69|71,72|74,93|96,96|98,98|104,104|108,108|111,116|128,135|146,154|187,187|190,240|244,245|252,252|256,256|259,260|262,266|272,272|278,282|292,345|347,349|352,414|417,419|424,442|444,561|567,569|579,579|587,590|593,593|596,596|609,618 Q:0,9|11,36|38,38|40,56|59,59|64,67|70,70|73,73|94,95|97,97|99,103|105,107|109,110|117,127|136,145|155,186|188,189|241,243|246,251|253,255|257,258|261,261|267,271|273,277|283,291|346,346|350,351|415,416|420,423|443,443|562,566|570,578|580,586|591,592|594,595|597,608 HHHHHHTTTB?HHHHSHHHHHHHHHHHHHHSEEEESS?B?HHHHHHHHHHHHHHHHH--S????SGGG??T--T-------------------?EE?B?TTTEE?EEE?SS??????SHHHHHHHHHS---?????HHHHHHHHHH?????????THHHHHHHHHHHHHHHTTSHHHHHHHHHHHTE-EE--------------------------------------------------?EEE--EEEEEE?TTT?EE??B?????TTTSS?SSEEE-----EEEEEEEEE?--??-------------------------------------------------S???SS---------------------------------------------------------------TT???EEEE-------------------E??????????-----------------------????????????-------------------------------------------------------------------??????EEEEE???EEEEEEEEE?TTEEEEE????TT?SS?EEEEEEEEEEEE?????????? 3MGU|A PF10643.4_Cytochrome-c551_seed 7 274 !Q:0,158|161,177|179,201|203,204|221,221|238,238|252,255|269,271|273,273 Q:159,160|178,178|202,202|205,220|222,237|239,251|256,268|272,272 ----------------------------------------------------------------------------------------------------------------------------?????????-------------------???????SS???-------------?T-----------------------T??HHHHHHHHHHHSSSSS?SGGGHHHHHHHTTTTT?HHHHHHHHHHSTT????HHHHHHHHHHHHH---H? 3A9F|A PF10659.4_Trypan_glycop_C_seed 103 148 !Q:1,1|3,4|7,7|11,19|23,23|26,27|33,33|35,36|38,40|44,47|53,69|74,80|83,86|88,109|113,114|116,147 Q:0,0|2,2|5,6|8,10|20,22|24,25|28,32|34,34|37,37|41,43|48,52|70,73|81,82|87,87|110,112|115,115 H-H--HS?TTT??-------TTS?EE--TTSSS?E--E???HHH----HHHHH-----------------TSSS-------SS????S---?------------------SSS--S??------------------------------ 2JWH|A PF10671.4_TcpQ_seed 60 126 !Q:0,2|4,6|10,10|24,31|33,33|37,39|41,43|46,49|51,52|58,59|62,62|66,74|83,84|95,95|99,104|110,124 Q:3,3|7,9|11,23|32,32|34,36|40,40|44,45|50,50|53,57|60,61|63,65|75,82|85,94|96,98|105,109|125,125 ???B???TTT?BHHHHHHHHHHHT--------T?EEE---E?-?SS--??B??STTTT??BS?HHH---------HHHHHHHH--HGGGTEEEEE?SSE------EEEEE???------------S 2L4W|A PF10672.4_Methyltrans_SAM_seed 3 286 !Q:0,0|10,10|13,15|30,34|48,48|57,57|65,72|80,82|97,97|103,104|106,107|124,124|131,131|145,145|154,154|170,172|181,181|194,194|201,203|206,208|238,239|243,243|255,258|265,267|271,272|275,275|279,279|286,286 Q:1,9|11,12|16,29|35,47|49,56|58,64|73,79|83,96|98,102|105,105|108,123|125,130|132,144|146,153|155,169|173,180|182,193|195,200|204,205|209,237|240,242|244,254|259,264|268,270|273,274|276,278|280,285 -EEEEGGGGT?TT---EEEEEETTEEEEEE?----SHHHHHTHHHHHH-HHHHHSTT?SEEEEEE????????EEEEEES???SSEEEEETTEEEEE?SSSTT??S??GGGHHHHHHHTTTTTT?EEEEES?TTTHHHHHHHHTT?SEEEEEES?TTHHHHHHHHHHHTT???TTEEEEES?HHHHHHHHHHTT?EEEEEE???SE???EEEHHHHHHHHHHHHHHTEEEEEEEEEEE??TTS?HHHHHHHHHTT?-??EEEEEE???TTS??TT?GGG?EEEEEE- 1WXX|A PF10674.4_Ycf54_seed 24 98 !Q:16,18|20,21|37,40|50,51|65,65|75,75|87,87|89,89 Q:0,15|19,19|22,36|41,49|52,64|66,74|76,86|88,88|90,97 EEEEEEEEEHHHHHTT---S??HHHHHHHHHHHHHTT????EEEEESBGG--GGSGGGHHHHHHS?SSEEEEEES?HHHHHHHHHHH?S?EEEEEEES 3JSR|A PF10683.4_DBD_Tnp_Hermes_seed 4 68 !Q:1,4|6,8|28,29|35,35|53,53|55,55|57,57|63,64 Q:0,0|5,5|9,27|30,34|36,52|54,54|56,56|58,62|65,67 S????B???HHHHHHHHHHHHHHHHHTT??GGGGG?HHHHHHHHHHHHHHHHH?S?B?HHHHS??HHH 2BW3|A PF10690.4_Myticin-prepro_seed 5 111 !Q:0,23|28,28|38,38|56,110 Q:24,27|29,37|39,55 -----------------------?HHHH-HHHHHHHTT?SEEEEEEETTEEEEEEE??----------------------------------------------------- 2EEM|A PF10692.4_DUF2498_seed 12 82 !Q:0,3|7,7|29,30|40,40|46,50|54,56|80,81 Q:4,6|8,28|31,39|41,45|51,53|57,79 ????EEE?HHHHHHHHHHHHHHHHHHHTT??EEEEEESSS?EEEEE?????TTS???HHHHHHHHHHHHHHHHHTTTEEE?? 3M92|A PF10694.4_DUF2500_seed 28 147 !Q:0,39|51,56|60,61|64,67|69,75|77,82|92,112|117,119|127,127|130,131|146,147 Q:40,50|57,59|62,63|68,68|76,76|83,91|113,116|120,126|128,129|132,145 ?------------------------------------???EEEEEEEEEEE??????GGG??SS????S-----??S----??EEEEEETTS??------------------?EEEE?-?HHHHTTS?TT??EEEEEETTEEEEEE?- 3RD4|A PF10702.4_DUF2507_seed 22 129 !Q:36,37|53,53|71,71|81,81|85,87|102,102|110,110|116,118|121,121 Q:0,35|38,52|54,70|72,80|82,84|88,101|103,109|111,115|119,120|122,128 EHHHHHHHHTTHHHHHHGGGHHHHHHHHHHHHHHHS??SSGGGHHHHHHHTTS?EEEEEEEETTEEEEEEE?HHHHHHHHH-SSS???HHHHHHHHHHHHHH?TTEEEEE-EEEEE?--SS?EEEEEEE 3NJC|A PF10715.4_REGB_T4_seed 14 182 !Q:0,2|35,43|47,50|52,62|65,66|80,81|95,96|107,107|109,109|115,116|119,119|122,123|127,134|148,149|152,154|156,156|168,169|172,177|179,181 Q:3,34|44,46|51,51|63,64|67,79|82,94|97,106|108,108|110,114|117,118|120,121|124,126|135,147|150,151|155,155|157,167|170,171|178,178 ???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---------HTS?-??E-----------EE??HHHHHHHHHTSTT??HHHHHHHHGGGGH--HHHHHHHSSS?S?SSSSS??SS?SS??SEE--------EEEETTEEEEEEE??SS???S-SSEEEEEEEEE??SS??????S??? 2HX6|A PF10722.4_YbjN_seed 185 195 !Q:12,13|15,17|19,20|23,27|31,31|36,48|64,75|80,80|83,88|98,114|135,135|137,138|141,141|149,153|160,166|169,170|195,195 Q:0,11|14,14|18,18|21,22|28,30|32,35|49,63|76,79|81,82|89,97|115,134|136,136|139,140|142,148|154,159|167,168|171,194 HHHHHHHHHHHH??S---S??EE-----EEE-TTEE-------------EEEEEETTEEEEEEE??----------SSTT?EE------EEEEEEEES?---------------?TTHHHHHHHHHHHTTTTTTT?E--EE-EETTEEE-----EEEEEE?------TT??HHHHHHHHHHHHHHHHHHHHHHHH- 4H5B|A PF10727.4_Rossmann-like_seed 8 137 !Q:0,19|25,26|28,30|32,32|42,42|47,47|53,73|77,77|83,86|89,89|101,104|107,107|112,113|116,117|129,129 Q:20,24|27,27|31,31|33,41|43,46|48,52|74,76|78,82|87,88|90,100|105,106|108,111|114,115|118,128|130,136 ????--------------??EEEEE??S???S?HHHHHHHTT?EEEE?SSGGG---------------------GGG?SEEEE---?SS?HHHHHHHHHTT--??TT?EEEE??SS??GGGGHHHHHTT?EEEEEEE 3D1L|A PF10728.4_DUF2520_seed 98 177 !Q:1,2|9,10|20,20|27,27|29,29|33,35|68,69|71,72|74,96|111,111|115,115|120,121|126,131|134,134|137,141|153,161 Q:0,0|3,8|11,19|21,26|28,28|30,32|36,67|70,70|73,73|97,110|112,114|116,119|122,125|132,133|135,136|142,152|162,176 T??EEEEES--SHHHHHHHH-HHHHTT?S?EEE?-?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT--T??G-----------------------GGGHHHHHHHHHHH-HHS?HHHH??STTT------TT?HH-----HHHHHHHHTTT----?----HHHHHHHHHHHHHHH 3D1L|A PF10729.4_CedA_seed 3 80 !Q:0,20|26,26|28,28|32,32|46,47|51,53|55,57|75,75|78,79 Q:21,25|27,27|29,31|33,45|48,50|54,54|58,74|76,77 ?????????????????????BTTBS?B?TTT?TTEEEETTEEEEB??SSS???B???BSSHHHHHHHHHHHHHT?SS?? 2BN8|A PF10731.4_Anophelin_seed 4 66 !Q:0,54|63,63|65,65 Q:55,62|64,64 ----------------------?????????????????????????????????SSTTTTSS?S? 4E05|I PF10740.4_DUF2529_seed 14 174 !Q:16,16|38,39|45,45|61,62|68,69|72,79|82,82|90,90|92,93|108,109|115,116|119,121|127,127|131,131|134,137|139,139|143,143|146,146|148,148|151,153 Q:0,15|17,37|40,44|46,60|63,67|70,71|80,81|83,89|91,91|94,107|110,114|117,118|122,126|128,130|132,133|138,138|140,142|144,145|147,147|149,150|154,173 HHHHHHHHHHHHHHHH-GGGHHHHHHHHHHHHHHHHTT??EEEEE?GGGGGGTHHHHTSTT??TTEEE??TT??----??TT?EEEEEES?S??HHHHHHHHHHHHHT??EEEEE--SS???TTGGG-SSS?EE????S?SEE?TT-S?EE???HHHHHHHHHHHHHHHHHHHH 3JX9|A PF10763.4_DUF2584_seed 9 82 !Q:0,1|7,7|12,13|15,16|19,20|33,33|36,37|48,53|80,81 Q:2,6|8,11|14,14|17,18|21,32|34,35|38,47|54,79 ??EEEEE?SSEE??S??EE--SSSSEEEEEEES?EE??SSSEEEEESS??????EEEEEEEEEEETTEEEEEEEEEEESS?? 2NWA|A PF10771.4_DUF2582_seed 23 88 !Q:0,1|5,16|31,34|37,37|43,45|50,52|73,77 Q:2,4|17,30|35,36|38,42|46,49|53,72|78,87 ??HHH------------HHHHHHHHHHHHHH--??SB?HHHHH---HHHT?-?HHHHHHHHHHHHTTTSEEEE-----EETTEEEEEE 2L02|A PF10778.4_DehI_seed 12 165 !Q:1,2|43,51|53,55|64,66|97,97|102,104|106,113|120,122|124,125|129,129|132,136|141,141|157,157|160,161 Q:0,0|3,42|52,52|56,63|67,96|98,101|105,105|114,119|123,123|126,128|130,131|137,140|142,156|158,159|162,164 S??HHHHHHTTSTTHHHHHHHHHTTGGGBHHHHHHHHHHHHHT---????-?S???HHHHHHHT???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHTT???B???---??HHHHSB???S??TTS?SS?????GGGS?HHHHHHHHHHHHHTT?SS??HHH 3BJX|A PF10784.4_Plasmid_stab_B_seed 11 72 !Q:7,7|11,11|25,25|47,47|58,58|62,63 Q:0,6|8,10|12,24|26,46|48,57|59,61|64,71 EEEEEEE?TTS-HHHHHHHHHHHTS?HHHHHHHHHHHHHHHHHHHHH?THHHHHHHHH?STT??HHHHHHHH 2JD3|A PF10798.3_YmgB_seed 6 63 !Q:18,20|36,38|58,62 Q:0,17|21,35|39,57 HHHHHHHHHHHHHHHHTT???SHHHHHHHHHHHHHT???HHHHHHHHHHHHHHHHHHH??--? 2OXL|A PF10802.3_DUF2540_seed 12 77 !Q:6,8|22,27|38,40|47,48|60,60|75,76 Q:0,5|9,21|28,37|41,46|49,59|61,74 EEEESS???HHHHHHHHHHGGG?-????HHHHHHHHHS???EEEEEE??HHHHHHHHHHG-GGHHHHHHHHHHHH?? 2EFV|A PF10804.3_DUF2538_seed 3 156 !Q:0,12|36,37|53,53|59,59|79,79|83,83|97,97|104,104|120,122|126,126|135,136|154,155 Q:13,35|38,52|54,58|60,78|80,82|84,96|98,103|105,119|123,125|127,134|137,153 ------------?HHHHHHHHHHHHHHHHHHHHTTS??SSHHHHHHHHHHHHH?GGGTT?HHHHHHHHHHTSHHHHTTS?TTS?SSTTTTSEETTEE?HHHHTS?HHHHHHHHHHHHHTT???SSS?HHHHHHTT??HHHHHHHHHHHHHHTTT?? 3KBY|A PF10824.3_DUF2580_seed 56 108 !Q:0,0|2,9|11,11|32,34|40,42|51,51|54,55|92,94|97,98 Q:1,1|10,10|12,31|35,39|43,50|52,53|56,91|95,96|99,107 ?S--------S?HHHHHHHHHHHHHHHHHHHH---HHHHH---HHHHHHHH-TS??SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT???SS??GGGHHHHHH 4J7K|A PF10843.3_DUF2578_seed 12 203 !Q:0,36|42,56|76,76|79,79|83,83|90,91|101,101|106,106|109,109|113,113|138,138|141,143|151,151|166,174|191,191|193,193 Q:37,41|57,75|77,78|80,82|84,89|92,100|102,105|107,108|110,112|114,137|139,140|144,150|152,165|175,190|192,192|194,202 ??------------------------------?????EESSS---------------SEEESSHHHHHHHHHHHHH-TT?TTS?EEEEEE??HHHHHTTTT?GGGS?TT?STT?HHHHHHHHHHHHHTHHHHHHHHTT?TT???SEEEEEE?SSEEEEEEEEEEEE---------TTEEEEEEEEEEEESS?S?EEEEEEEEE 3BCY|A PF10862.3_FcoT_seed 6 164 !Q:10,12|17,26|42,43|46,46|51,52|55,56|80,81|87,88|105,106|110,110|112,114|126,127|131,131|134,135|137,137|149,153 Q:0,9|13,16|27,41|44,45|47,50|53,54|57,79|82,86|89,104|107,109|111,111|115,125|128,130|132,133|136,136|138,148|154,163 HHTHHHHTTT???EEEE----------EEEEETTEEEEEEEE??SS?SSSS??SS??SHHHHHHHHHHHHHHHHHHHHTT??STTTT??HHHHHHSHHHHEEEEE??EEE?S???SSSEEEEEEEE??EEE?SS--S?EEEEEEEEEEE?????EEEEEEEEEE 3B18|A PF10869.3_DUF2666_seed 9 140 !Q:20,21|25,25|50,53|64,65|67,68|70,73|87,98|110,117|123,124|127,128|137,139 Q:0,19|22,24|26,49|54,63|66,66|69,69|74,86|99,109|118,122|125,126|129,136 SSEEEEEEEETTEEEEEEEE??TTS?HHHHHHHHHHHHHHHHHHHHHHTT--??HHHHHHHTTT??S??S----HHHHHHHHHHHHT????--------HHHHHHHHHHH--------HHTTT??SS??HHHHHHHH??? 3V68|A PF10928.3_DUF2810_seed 12 54 !Q:4,4|10,11|28,28|32,32|43,43|46,46|53,53 Q:0,3|5,9|12,27|29,31|33,42|44,45|47,52 HHHS?SEEEE??HHHHHTHHHHHHHTTS?EEE?SSSHHHHHTT?SS?EEEESS? 2LF0|A PF10938.3_YfdX_seed 23 185 !Q:15,15|17,17|35,35|44,44|47,50|55,82|94,100|118,118|131,131|160,160|173,173|176,176|182,184 Q:0,14|16,16|18,34|36,43|45,46|51,54|83,93|101,117|119,130|132,159|161,172|174,175|177,181 HHHHHHHHHHHHHTT-T?HHHHHHHHHHHHHHHTS?HHHHHTTB?TT????SSSS---------------------------?EEEEEEEEEEE??-????HHHHHHHHHHHHHHHTT?HHHHHHHHHHTT?EEEEEEEEEEHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHH-HT?EEEEE??? 3DZA|A PF10976.3_DUF2790_seed 48 104 !Q:0,17|22,43|45,48|51,55|62,65|67,68|70,72|83,83|87,87|97,97|99,103 Q:18,21|44,44|49,50|56,61|66,66|69,69|73,82|84,86|88,96|98,98 -----------???????TTTT--------------------??B????TT?????SEEEEE??-?T--T??-SEEEEEEEEE?TTS?EEEEEEEEE?S-???? 4F98|A PF10980.3_DUF2787_seed 38 142 !Q:0,0|17,19|26,27|35,35|38,38|44,44|46,47|55,59|63,63|75,82|103,103|107,107|110,110|128,128|133,134 Q:1,16|20,25|28,34|36,37|39,43|45,45|48,54|60,62|64,74|83,102|104,106|108,109|111,127|129,132|135,141 ?HHHHHHHHTTTHHHHS--?STTTTT??EEEEEEE?TT?BTTTB?S??EEEEEEE----?TTS?EEEEEEEEEEE??-?????EEEEEEEETTTTEEEETTTE-EEE?TT?HHHHHHHHHHHHHHHHH-HHTT??SEEEEEE 2W56|A PF10982.3_DUF2789_seed 60 76 !Q:0,1|4,4|17,19|31,35|39,39|43,43|47,47|61,62 Q:2,3|5,16|20,30|36,38|40,42|44,46|48,60|63,75 ??TT?THHHHHHHHHTS???HHHHHHHHHHS?--??TTS?STT?TTS?HHHHHHHHHHHHS??TTHHHHHHHHHHH 2KP6|A PF10988.3_DUF2807_seed 118 290 !Q:0,1|6,6|11,11|17,17|19,23|26,27|38,38|47,48|50,52|61,61|63,66|73,73|75,89|93,93|95,95|104,106|115,116|121,121|123,123|137,137|142,142|144,144|155,166|170,170|190,190|194,194|197,216|225,225|229,234|237,237|246,246|258,258|264,264|275,276|279,279|285,286|288,289 Q:2,5|7,10|12,16|18,18|24,25|28,37|39,46|49,49|53,60|62,62|67,72|74,74|90,92|94,94|96,103|107,114|117,120|122,122|124,136|138,141|143,143|145,154|167,169|171,189|191,193|195,196|217,224|226,228|235,236|238,245|247,257|259,263|265,274|277,278|280,284|287,287 ??SEEE-EESS?EEEEE-E---?-SS??EEEEEEEGGG-GGGEEEEE--E---TTEEEEEE?B---?TTTTTS?B--------------?EEE?S?EEEEEEES?-?SEEEEESS-?EEEE?S?EEEEEEEEEEESS?EEEE?S?EEEEEEEEEE------------ESS?EEEEEEEEEEEEEEEEESS?EEE-EE--------------------EEEEEEEE-EEE------SS?EEEEEEEE-EEEEEEEEESS?EEEEE-EEEEEEEEEE--SS?EEEEE--S?? 3JX8|A PF10991.3_DUF2815_seed 20 232 !Q:4,5|8,8|14,14|21,21|23,23|26,33|41,47|52,52|72,72|76,79|81,84|90,90|92,92|95,95|100,105|111,116|127,132|135,140|144,144|146,166|171,171|174,174|205,216|221,231 Q:0,3|6,7|9,13|15,20|22,22|24,25|34,40|48,51|53,71|73,75|80,80|85,89|91,91|93,94|96,99|106,110|117,126|133,134|141,143|145,145|167,170|172,173|175,204|217,220 TEEE??TT?EEEEE-EEEEEE?S-TT?-----??EEEEEEE-------EETT?HHHHHHHHHHHHHHHHHHH-HHH---?S????GGGSB?S?EE-TTTS?--??-GGGTT------EEEEEEEESS---???EE-----?TTS?B---------------?---??GGGS?TT?EEEEEEEEEEEEETTEEEEEEEEEEEEEEE??????-???-?GGGT????---???? 4KLK|A PF10996.3_Beta-Casp_seed 183 255 !Q:7,13|20,22|26,45|47,54|60,60|71,72|74,75|80,90|97,140|143,143|146,151|156,158|160,160|165,195|201,201|204,204|209,212|224,224|227,227|229,229|233,233|235,240|243,243|246,251 Q:0,6|14,19|23,25|46,46|55,59|61,70|73,73|76,79|91,96|141,142|144,145|152,155|159,159|161,164|196,200|202,203|205,208|213,223|225,226|228,228|230,232|234,234|241,242|244,245|252,254 HHHHHHH-------HHHHHH---HTS--------------------S?----???EEEES-SHHHHHHHHH--H?-GGGS?----------HHHHHH????-----------------------------------??-??TT?TT------EEEE???H-HHHH--------?--????-?-?--------?---EEEES?TT-SSSS----HHHHHHHHHSS?TT?E-EEE?S---???TT?HH------HHH 3AF6|A PF11009.3_DUF2847_seed 34 106 !Q:3,4|16,18|27,27|30,30|49,53|75,78|99,99 Q:0,2|5,15|19,26|28,29|31,48|54,74|79,98|100,105 EEE??SHHHHHHHHHH--?SEEEEEEE?TT?HHHHHHHHHHHHHHHHHT---??EEEEEGGGGHHHHHHHHHHHT????SSEEEEEETTEEEEEEEGGG?SHHHHH 3IV4|A PF11015.3_DUF2853_seed 29 107 !Q:11,16|28,28|30,31|33,33|39,40|43,43|60,63|65,66|82,82|85,85|87,88|103,103 Q:0,10|17,27|29,29|32,32|34,38|41,42|44,59|64,64|67,81|83,84|86,86|89,102|104,106 HHHHHHHHHTT???-??HHHHHHHHHHH?S??S?HHHHB??TT?HHHHHHHHHHTTTTTS??-?S--SHHHHHHHHHHHHHH?TT?S??BHHHHHHHHHHHTT?GGG 2PYQ|A PF11032.3_ApoM_seed 4 193 !Q:0,15|17,26|28,29|31,31|43,43|54,54|76,76|94,94|104,105|108,110|116,116|119,119|125,129|141,142|158,159|175,176|181,184|186,192 Q:16,16|27,27|30,30|32,42|44,53|55,75|77,93|95,103|106,107|111,115|117,118|120,124|130,140|143,157|160,174|177,180|185,185 -------------???S?---??????B??S?STTGGGTTGGG?EEEEEEEEEE-SSGGGTGGGTTEEEEEEEEEE?SSTTEEEEEEEEEETTS?EEEEEEEEE??TT???BEESS?TT?EEEEE?---?SSTTEEEEEEE--ETTEEEEEEEESSSS??HHHHHHHHHHHHHTT??EEEE????S??????? 2WEW|A PF11033.3_ComJ_seed 7 135 !Q:0,1|5,6|11,11|23,31|50,50|64,71|85,85|90,90|94,95|99,101|113,116|120,120|125,125|134,134 Q:2,4|7,10|12,22|32,49|51,63|72,84|86,89|91,93|96,98|102,112|117,119|121,124|126,133 ??EEE??EEEE?BTTEEEEEETT?????????HHHHHHTEEEETTEEEEE?SSSSEEEEEEEES????????SEEEEEEEEESSS?EEEE?TTS??EEE???SEEEEEEEEEE?---TTT?TTSS?EEEEEEEE? 4MQD|A PF11053.3_DNA_Packaging_seed 7 166 !Q:0,43|84,85|117,165 Q:44,83|86,116 -----------------------------??-????????????TTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?--------------------????----------------------?? 3TXS|A PF11068.3_YlqD_seed 29 140 !Q:3,3|12,13|55,55|58,58|97,97|100,100|110,111|114,114|117,117|124,125 Q:0,2|4,11|14,54|56,57|59,96|98,99|101,109|112,113|115,116|118,123|126,139 EEB?EEEEEEEE??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS?TT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS?TT?EEEEEEEEE??EE?TT?BHHHHS-?EEEEEETTEEEEEE 4DCI|A PF11095.3_Gemin7_seed 7 82 !Q:34,34|36,37|46,46|49,50|58,59|62,63|80,81 Q:0,33|35,35|38,45|47,48|51,57|60,61|64,79 HHHHHHHHHHHHHHHHHHHHHHTTSEEEEEEGGG?E--EEEEEEEE?TT??EEEEEEE??TT??EEEEEEEGGGEEEEEE?? 1Y96|B PF11099.3_M11L_seed 9 195 !Q:16,17|43,44|65,78|84,86|101,103|121,123|139,146|156,180|182,195 Q:0,15|18,42|45,64|79,83|87,100|104,120|124,138|147,155|181,181 HHHHHHHHHHTGGGGG??SHHHHHHHHHHHHHHHHHHHHHHHH??HHHHHHHHHHHHHHHHHHHH??????????---?TTSSS?-?HHHHHHHHHHHHHH???HHHHHHHHHHHHHHHHH???HHHHHHHHHHHHHHH??------HHHHHHHHH-------------------------H?------------- 2JBX|A PF11102.3_Cap_synth_GfcB_seed 39 274 !Q:0,18|28,40|43,49|56,57|60,60|69,71|82,94|101,101|104,105|123,125|131,141|146,146|154,160|163,163|175,181|207,207|224,229|233,236|248,253|265,265|273,273 Q:19,27|41,42|50,55|58,59|61,68|72,81|95,100|102,103|106,122|126,130|142,145|147,153|161,162|164,174|182,206|208,223|230,232|237,247|254,264|266,272 ----???---------???HHHHHHHHH-------------HH???????HHHHHH-?SS?EEEEEETT???EEEEEEEEET-------------TEEEEE?TT??EEEEETTEEEEEESSSS--?EEEES-----------SGGG?GGGGGGG?-----?TT?EEEEEEEEEET-------TEEEEEEEEEEEEEEEEEEEEETTE-EEEEEEEEEEEEETTT------TEE----EEEEEEEETTT??----EEEEEEESSSS?SEEEEEE? 2IN5|A PF11104.3_PilM_2_seed 37 396 !Q:4,4|16,16|19,20|25,26|33,34|45,45|62,65|72,72|76,76|85,88|97,97|105,105|108,111|121,121|125,125|127,127|135,136|154,158|163,163|178,178|187,194|198,199|203,223|228,228|231,231|250,250|265,266|276,301|323,329|359,360|367,368|373,373 Q:0,3|5,15|17,18|21,24|27,32|35,44|46,61|66,71|73,75|77,84|89,96|98,104|106,107|112,120|122,124|126,126|128,134|137,153|159,162|164,177|179,186|195,197|200,202|224,227|229,230|232,249|251,264|267,275|302,322|330,358|361,366|369,372|374,395 EEEE?SSEEEEEEEET-TT--TEEE--EEEEEE??TTSEETTEES?HHHHHHHHHHHHHHHT????EEEEEE?GGG?EEEEEEEE??-?HHHHHHHH-HHHHGGG?SS????EEEEEEESS?GGG-S?TTSEEEE--EEEEEEHHHHHHHHHHH-----HHTT?EEEEEEEHHHHTTG-GGHHHHHT--------STT?-EEE---------------------EEEE?SS?EEEEEEETTEEEEEEEES?SHHHHHHHHHHHTT??HHHHHHHHH??????-------------???????HHHHHHHHHHHHHHHHHHHHH????-??SEEEEESGGGGSTTHHHHHHHHHTSEEEE??GGGGSB??TTTS?HHHHHHHHHHHHHHHHHHHHHT 2YCH|A PF11107.3_FANCF_seed 7 444 !Q:0,187|195,211|221,233|242,243|247,247|261,285|295,298|310,310|321,321|339,365|376,376|381,383|395,396|400,400|404,405|421,424|426,428|433,433|443,443 Q:188,194|212,220|234,241|244,246|248,260|286,294|299,309|311,320|322,338|366,375|377,380|384,394|397,399|401,403|406,420|425,425|429,432|434,442 ----------------??-----------------------------------------------------?????----------------------------------------------------------------------------?---------------------------------??HHHHHHH-----------------HHHHHHHHS????--???-???HHHHHHHH--HHS?HHHHHHHHHHHHT?????-???????????????????HHHHHHHHH---?HHHHHHHHHHS?HHHHHHHHHH?GGGHHHHHHHHHHHHHT?--------------------------EEETTTTEEE?SSTT???HHHHHHHHHHH--HTS?HHH--HHHHHHHHHHHHHHT----T???STTS?HHHHHHHHH? 2IQC|A PF11108.3_Phage_glycop_gL_seed 9 121 !Q:0,8|11,15|19,20|25,26|30,30|34,35|43,43|52,54|78,79|97,97|105,105|107,120 Q:9,10|16,18|21,24|27,29|31,33|36,42|44,51|55,77|80,96|98,104|106,106 ?????????SS?-???TTT??EEEE??SSS-SSS??EEEEEEE?TTTTSSEE---EEEEEHHHHHHHHHHHHHTTGGG??THHHHHHHHHHHHHTTS?GGGGGGS?S???----------- 3PHF|2 PF11133.3_Phage_head_fibr_seed 3 305 !Q:0,126|130,130|133,134|143,144|154,156|166,168|178,178|181,183|190,195|199,201|209,220|225,227|237,239|252,259|261,262|266,267|269,281|304,304 Q:127,129|131,132|135,142|145,153|157,165|169,177|179,180|184,189|196,198|202,208|221,224|228,236|240,251|260,260|263,265|268,268|282,303 -----------------------------------------------------------------------------------------------------------------??--??????????GGG?TT??HHHHHHHH??SHHHHHHHH???HHHHHHHTT???HHHHHHHHH-HH???HHHHHH------HTT???HHHHHHH------------HHHH???HHHHHHHTT???HHHHHHHHHHHT????????B??SSS??B?????????????SHHHHHHHHHHHHHHHHHTTSS? 3QC7|A PF11155.3_DUF2935_seed 73 184 !Q:27,27|30,34|48,48|59,60|64,122|136,136|156,156|160,163 Q:0,26|28,29|35,47|49,58|61,63|123,135|137,155|157,159|164,183 HHHHHHHHHHHHHHHHHHHHHHHHHTS?TT?----HHHHHHHHHHHHH-HHHHHHHHTT??TTS----------------------------------------------------------?HHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHTT?STT????HHHHHHHHHHHHHHHHHHHH 3D19|A PF11175.3_DUF2961_seed 37 362 !Q:1,1|14,14|17,17|29,30|33,41|44,44|50,51|57,63|68,70|76,76|84,84|88,88|90,90|99,99|102,106|109,110|113,114|119,119|121,124|130,133|136,140|147,152|155,155|158,158|164,164|177,179|184,196|201,213|221,223|226,226|230,230|232,232|239,240|243,258|269,271|276,276|278,298|306,306|310,310|322,333|338,338|340,347|356,358 Q:0,0|2,13|15,16|18,28|31,32|42,43|45,49|52,56|64,67|71,75|77,83|85,87|89,89|91,98|100,101|107,108|111,112|115,118|120,120|125,129|134,135|141,146|153,154|156,157|159,163|165,176|180,183|197,200|214,220|224,225|227,229|231,231|233,238|241,242|259,268|272,275|277,277|299,305|307,309|311,321|334,337|339,339|348,355|359,361 S?GGGEEEEEEETT?SS?SEEEEHHHHTT??TT-----????EE?SSEEE--ESSTT------?EEEE???EEESS?EEEEEEE?SSS?B?EEEEEEEE-EE?----SS??TT??EEEE-E----EEEEE????TT?--??GGGSSS????-?SS?TT?EEEEE-EESSEEEEEEEE---EEEE-------------SSSS-----???--???EEEEETT?--SS?SEE?S?HHHHTT??SS------------????EEETTEEEEE???SSTT?E---------------------EEEEEEE?SSS?EEESSEEEEEE?-----------SSGG-G----????EEEEEEEE---EES 4KQ7|A PF11176.3_DUF2962_seed 31 216 !Q:0,34|37,41|44,47|50,50|66,83|88,92|102,120|127,128|139,142|147,149|169,170|177,177|179,180|190,195|197,197|199,199|203,204|209,209 Q:35,36|42,43|48,49|51,65|84,87|93,101|121,126|129,138|143,146|150,168|171,176|178,178|181,189|196,196|198,198|200,202|205,208|210,215 ------?-----------------------?????SS?????SS????HH-HHHHHHHHHHHHHST------------------TTTT?????HHHHHHHHH-------------------HHHHHH--HHHHHHHHHH----GGGT???TTHHHHHHHHHHHHHHHHH--TTEEEE?S??HHHHHHHHT-?----S-S?STH--HHHS?EEEEET 2KKM|A PF11183.3_PmrD_seed 3 84 !Q:0,1|9,11|15,16|37,37|40,42|45,45|48,48|73,74 Q:2,8|12,14|17,36|38,39|43,44|46,47|49,72|75,83 ??EEEEEEE???TTS-?EEEEEEETTSSSBEEEEEEE-SS???TT?EE?BSSSSEEEEBTEEEEEEEEEEEEE??HHHHHHHHH 2RQX|A PF11217.3_DUF3013_seed 12 165 !Q:0,4|17,17|43,44|46,49|51,60|72,72|76,79|81,81|87,87|91,92|96,96|125,125|127,127|130,138|149,150|156,158|161,164 Q:5,16|18,42|45,45|50,50|61,71|73,75|80,80|82,86|88,90|93,95|97,124|126,126|128,129|139,148|151,155|159,160 ?????HHHHHHHHHHHH?TTSEEEEEEETTTTEEEEEEEEEEE??S????S??????????EEEEEEEEEEE?TTT-???B-GGGSS?EEE??GGG?EEHHHHHHHHHHHHHHHHHHHHHHHHHT-T?TT?????????HHHHHHHHHH--HHTTS???EE???? 3NAT|A PF11221.3_Med21_seed 30 221 !Q:0,3|5,11|41,138|167,167|173,173|179,179|218,220 Q:4,4|12,40|139,166|168,172|174,178|180,217 ????H-------HHHHHHHHHHHHHTTTTHHHHHHTTGGGG?????-----------------------??????????----------------------------------------------------------??HHHHHHHHHHHHHHHHHHHHHHHHHHHH?TTSSS?HHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??? 1YKH|B PF11232.3_Med25_seed 7 166 !Q:0,3|18,21|26,26|29,31|46,51|55,56|77,77|88,88|91,91|103,105|115,119|122,124|126,127|134,134|138,138 Q:4,17|22,25|27,28|32,45|52,54|57,76|78,87|89,90|92,102|106,114|120,121|125,125|128,133|135,137|139,165 ????SSEEEEEEEEEEEE????SSSS?TT???EEEEEEEEEEETTS-?--??GGG??SEEEEEEEEHHHHHHHGGGG-SSEEEEEEEE?SS?HHHHHHHHHHH---HHHEEEEEE?---?TT???S??EEEEEE?TTT?SEEEEEESSHHHHHHHHHHHHHHHHTT 2L6U|A PF11258.3_DUF3048_seed 32 342 !Q:3,4|6,9|16,18|24,25|27,27|31,31|33,33|39,39|47,47|51,51|60,64|67,68|73,73|75,76|78,78|89,89|91,91|97,97|99,104|116,118|120,120|125,129|133,134|140,142|145,146|150,150|153,156|158,158|173,173|176,178|180,186|188,206|212,214|217,219|241,241|247,250|254,255|264,264|269,272|276,277|280,281|284,284|286,291|293,293|296,297|314,315|324,326|332,333|335,335|338,338 Q:0,2|5,5|10,15|19,23|26,26|28,30|32,32|34,38|40,46|48,50|52,59|65,66|69,72|74,74|77,77|79,88|90,90|92,96|98,98|105,115|119,119|121,124|130,132|135,139|143,144|147,149|151,152|157,157|159,172|174,175|179,179|187,187|207,211|215,216|220,240|242,246|251,253|256,263|265,268|273,275|278,279|282,283|285,285|292,292|294,295|298,313|316,323|327,331|334,334|336,337|339,341 TTT??B??--GGGGGB-??EEEEE??S-GGG?S?BSTTS?SEEEEEE?STT?EEEEEEES-----SS??SEEB?B??B?HHHHHHHHTT-T?EEEES?B?-----HHHHHHHHTTS---S?EEEH-----HHH--BTTTB---EE-?SSS?TT----S?EEEEHHHHHHHHHH-HT???B???????B?-------???????????EEEEE???SS???EEEEEEETTTTEEEEEETTEE?EETTT----TEE??BSEEEEEE?EEEE?---SSS??EE--EE?S------S?EE--EEEEETTEEEEEEEEE--ETTEEEEE---ETTEE??B?SS?EEE 2PSB|A PF11260.3_Spidroin_MaSp_seed 26 90 !Q:25,30|33,33|52,52|56,56|81,85 Q:0,24|31,32|34,51|53,55|57,80|86,89 HHHHHHTSHHHHHHHHHHHHHHHHH-----?TT?HHHHHHHHHHHHHHHHHH?SSS?HHHHHHHHHHHHHHHHHHHHHHSB?????STTH 2M0M|A PF11266.3_DUF3066_seed 15 219 !Q:0,0|35,35|65,68|91,91|119,119|182,183|204,205|217,218 Q:1,34|36,64|69,90|92,118|120,181|184,203|206,216 ?TTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?GGGHHHHHHHHHHHHHHHHHHHHHHHHTT????HHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHTHHHHHHHHHHHHHGGGS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHHHHT??HHHHHHHHGGG?? 2OC5|A PF11267.3_DUF3067_seed 16 111 !Q:14,14|26,30|45,45|48,48|68,68|79,83|86,89|92,92|98,102 Q:0,13|15,25|31,44|46,47|49,67|69,78|84,85|90,91|93,97|103,110 HHHHHHHHHHHHSS?EEEEEEEETTE-----EEEEEEEEETTSTT?SS?HHHHHHHHHHHHHHHHHHS?HHHHHHHHHH?????BT----TB?EEEEE??---HHHHHHHH 2LJW|A PF11269.3_DUF3069_seed 12 125 !Q:2,2|7,7|27,27|37,37|45,45|47,47|55,55|67,70|82,82|89,89|112,112 Q:0,1|3,6|8,26|28,36|38,44|46,46|48,54|56,66|71,81|83,88|90,111|113,124 TS?GGGS?HHHHHHHHHHHHHHHHTTT?HHHHHHHHS?HHHHTSS?H-HHHHHHH-HHHHHHHHHHH??-?HHHHHHTTTTS?HHHHHH-HHHHHHHTHHHHHHHHHHHHTT?HHHHHHHHHHHT 2PV4|A PF11306.3_DUF3108_seed 135 389 !Q:0,48|51,52|55,70|72,72|81,81|84,90|102,105|123,123|126,127|130,137|160,164|172,173|179,181|183,183|186,188|190,190|195,196|200,231|245,257|268,272|274,286|290,290|295,295|301,301|309,320|327,327|330,330|333,333|346,355|357,357|369,375|377,377|388,388 Q:49,50|53,54|71,71|73,80|82,83|91,101|106,122|124,125|128,129|138,159|165,171|174,178|182,182|184,185|189,189|191,194|197,199|232,244|258,267|273,273|287,289|291,294|296,300|302,308|321,326|328,329|331,332|334,345|356,356|358,368|376,376|378,387 -----------????--------------------------------??SS??ST----------------T?EEEEEEEE-TT?-----?EEEEEEEEEEE----EEEETTEEEEEEEEEEE?TT??EE--------EEEEEEEEEETTEEEEEGGGGG----?SHHHHTT??TTEEE???E-EE???T-TSTT??TTS???---------------------------??EEEEEEETTEEEE-------------EEEEEEEEEE-----E-------------EEE-EEEE-ETTEE-EEEEEEE------------EEEEEE?SS?SS?EEEEEEEEEETT----------T-EEEEEEEEETT-------S?EEEEEEEEEE? 4FVS|A PF11342.3_DUF3144_seed 20 87 !Q:1,1|22,29|53,53 Q:0,0|2,21|30,52|54,86 S?HHHHHHHHHHHHHHHTSTTS?-------HHHHHHHHHHHHHHHSGGGGGGT?SSHHHHHTTHHHHHHHHHGGGHHHHHHHHHHHH 2LYY|A PF11356.3_Pilus_PilP_seed 91 108 !Q:0,3|6,6|10,27|29,30|32,33|35,37|39,41|48,50|56,56|62,63|67,68|72,72|77,77|81,83|92,93|98,98 Q:4,5|7,9|28,28|31,31|34,34|38,38|42,47|51,55|57,61|64,66|69,71|73,76|78,80|84,91|94,97|99,107 ????SS?GGG------------------G??S??S???S---EEEEEE?-?SSSSS?EEEEE--SSS??EEE?TTEE?SSS-??EEEEEETT--EEEE-EETTEEEEE 3OSS|C PF11367.3_DUF3168_seed 123 201 !Q:8,9|11,13|19,19|21,29|32,36|39,47|50,52|54,59|67,68|71,71|73,74|77,82|85,86|88,90|98,100|102,109|111,118|122,122|124,125|129,132|141,141|145,151|154,155|158,158|161,161|164,176|179,187|189,193 Q:0,7|10,10|14,18|20,20|30,31|37,38|48,49|53,53|60,66|69,70|72,72|75,76|83,84|87,87|91,97|101,101|110,110|119,121|123,123|126,128|133,140|142,144|152,153|156,157|159,160|162,163|177,178|188,188|194,200 HHHHHHHH?-T---TTTTT?S?--------EE-----SS??-------TT---S-----?SSEEEEE??TT?S?-SS?---??SS--S--?EEEEEEE---E---?---?S?-------HHH-H--HHH----HHHHHHHH-TTS?-----?EE--TT-EE?EE?????????--??TT??-----??E-----EEEEEEE 2LFP|A PF11396.3_DUF2874_seed 181 82 !Q:2,4|9,9|12,15|24,26|29,31|35,38|48,51|60,67|70,70|75,75|79,79 Q:0,1|5,8|10,11|16,23|27,28|32,34|39,47|52,59|68,69|71,74|76,78|80,81 EE?-?GGGS?HH----HHHHHHHH--?TT??-EEE----EEEEEETTE----EEEEEEET--------TS?EEEE?TTS?EE 3DB7|A PF11401.3_Tetrabrachion_seed 2 49 !Q: Q:0,48 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 1YBK|A PF11402.3_Antifungal_prot_seed 6 53 !Q:0,0|5,7|10,11|27,27|29,29|33,36|40,41 Q:1,4|8,9|12,26|28,28|30,32|37,39|42,52 ?EEEE???SS??EEEEEETTTEEEEEE?S?TTT????STT??EEEETTTTEEE 2KCN|A PF11403.3_Yeast_MT_seed 2 40 !Q:0,3|5,8|16,16|23,26|29,31|35,39 Q:4,4|9,15|17,22|27,28|32,34 ????S????SSSTTTT?TTSSSS????TT???STT????? 1AQQ|A PF11404.3_Potassium_chann_seed 2 31 !Q:0,2|10,10|13,14|17,19|23,23|30,30 Q:3,9|11,12|15,16|20,22|24,29 ???SSBSSSS-SS??SS???TTS?BSTTTT? 1ZTN|A PF11405.3_Inhibitor_I67_seed 2 41 !Q:0,1|4,4|7,10|13,14|17,17|21,22|27,28|30,34|38,40 Q:2,3|5,6|11,12|15,16|18,20|23,26|29,29|35,37 ??SS?EE????SS??TT?SSB??BTTB??B?????SSS??? 2BI6|H PF11406.3_Tachystatin_A_seed 2 44 !Q:0,5|11,11|13,14|18,18|20,23|26,26|35,35|37,37|42,43 Q:6,10|12,12|15,17|19,19|24,25|27,34|36,36|38,41 ??????TTEEE?S??TTS?S????TT?EEEESSTT?S?EEEE?? 1CIX|A PF11407.3_RestrictionMunI_seed 2 203 !Q:0,10|22,25|45,46|55,58|66,68|70,71|75,81|91,92|101,105|109,110|115,117|139,142|146,146|159,159|173,173|181,181|184,185|202,202 Q:11,21|26,44|47,54|59,65|69,69|72,74|82,90|93,100|106,108|111,114|118,138|143,145|147,158|160,172|174,180|182,183|186,201 ???????????HHHHHHHHHTT????HHHHHHHHTTTSSEEEEES??TTSSSSTT????HHHHHHS???S??GGG???????SEEEEETTT??EEEEEEEE?????TTS?-GGGG???GGGGGGGGGSHHHHHHHHHHH????TTS?SEEEEEESGGGG?HHHHHHHHHHHTT?TTSEEEE?TT??HHHHHHHHHHHTGGGG? 1D02|A PF11408.3_Helicase_Sgs1_seed 5 82 !Q:0,2|25,26|28,28|31,32|43,45|55,57|61,61 Q:3,24|27,27|29,30|33,42|46,54|58,60|62,81 ???HHHHHHHHHHHHHHHHHHSSSS??S?SS-?HHHHHHHHHH???SHHHHGGGS???HHH-HHHGGGTHHHHHHHHHHTTT 1D8B|A PF11409.3_SARA_seed 3 41 !Q:0,4|7,7|12,12|14,14|16,16|25,25|30,32|37,40 Q:5,6|8,11|13,13|15,15|17,24|26,29|33,36 ?????TT?GGGT?B?S?HHHHHTTT?TTSS???EEEE???? 1DEV|B PF11410.3_Antifungal_pept_seed 8 40 !Q:0,1|11,11|14,16|20,20|23,26|29,30|37,39 Q:2,10|12,13|17,19|21,22|27,28|31,36 ??SSSSEEESS?SS???TTS?EE?-?-SS--SSSEEE??? 1DKC|A PF11411.3_DNA_ligase_IV_seed 7 36 !Q:0,7|10,10|14,14|19,21|32,35 Q:8,9|11,13|15,18|22,31 ????????SB?TTS?BSSS???HHHHHHHHHT???? 1IK9|C PF11412.3_DsbC_seed 187 168 !Q:2,5|10,10|16,21|27,29|37,37|39,39|49,58|61,65|72,75|77,85|87,89|94,94|99,99|105,106|115,116|122,133|137,139|146,146|151,151|156,158|165,167 Q:0,1|6,9|11,15|22,26|30,36|38,38|40,48|59,60|66,71|76,76|86,86|90,93|95,98|100,104|107,114|117,121|134,136|140,145|147,150|152,155|159,164 SS????HHHH-EEEEE------EEETT---EEEEEEE-E?TTEEEEGGG?---------EE-----EEEEEE----E????????-E---EEEE-TTTE-EEEEE?-SEEEEEEE--EEEEE------------EEE---EEEEEE?EEET-TTEE???EEEEEE??? 1L6P|A PF11413.3_HIF-1_seed 17 35 !Q:0,15|17,23|26,26|29,34 Q:16,16|24,25|27,28 ????????????????B????-??EE?TT?????? 3HQU|S PF11414.3_Suppressor_APC_seed 13 84 !Q:0,5|46,54|80,81 Q:6,45|55,79|82,83 ??????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??????-??HHHHHHHHHHHHHHHHHHHHHHHHH??SH 1M5I|A PF11415.3_Toxin_37_seed 8 35 !Q:0,1|14,14|32,34 Q:2,13|15,31 ??HHHHHHHHHHHS?TTEEEEEEETTEEEEEE??? 1MM0|A PF11416.3_Sed5p_seed 11 29 !Q:1,1|6,6|21,28 Q:0,0|2,5|7,20 H-HHHB?HHHHHHHHHHHHHH???????? 1MQS|B PF11417.3_Inhibitor_G39P_seed 2 71 !Q:0,1|18,20|23,25|43,43|58,58|61,63|68,70 Q:2,17|21,22|26,42|44,57|59,60|64,67 ??HHHHHHHHHHHHHHST---TT???TTHHHHHHHHHHHHTTS?HHHHHHHHHHHHHH?SS???GGGG??? 1NO1|A PF11418.3_Scaffolding_pro_seed 3 102 !Q:0,2|15,15|19,19|67,69|79,101 Q:3,14|16,18|20,66|70,78 ???HHHHHHHHHHHH?TTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHHHHH??--??????????????????? 3OA7|A PF11419.3_DUF3194_seed 4 87 !Q:2,2|6,6|30,30|34,34|44,44|59,60|63,66 Q:0,1|3,5|7,29|31,33|35,43|45,58|61,62|67,86 EE?TTS?HHHHHHHHHHHHHHHHHHHHHHS?GGG?SEEEEEEEE?TTTSSEEEEEEEEE??TT????HHHHHHHHHHHHHHHHHHHH 1PU1|A PF11420.3_Subtilosin_A_seed 2 35 !Q:0,1|7,7|9,13|18,20|22,23|25,25|34,34 Q:2,6|8,8|14,17|21,21|24,24|26,33 ??STTTT?S?????TTTT???S??S?TTHHHHHH? 1PXQ|A PF11421.3_Synthase_beta_seed 12 58 !Q:0,2|19,19|25,26|39,39|42,46|48,48 Q:3,18|20,24|27,38|40,41|47,47|49,57 ???SHHHHHHHHHHHTTSS?SSSST--GGGGTTTTSTTT-ST-----T?SHHHHHHHH 1PYV|A PF11422.3_IBP39_seed 7 215 !Q:0,6|8,9|34,35|51,69|71,71|75,75|79,86|96,97|100,100|117,117|138,138|140,143|154,155|158,158|163,163|174,174|177,178|185,185|189,190|194,195|198,198|201,202|206,206 Q:7,7|10,33|36,50|70,70|72,74|76,78|87,95|98,99|101,116|118,137|139,139|144,153|156,157|159,162|164,173|175,176|179,184|186,188|191,193|196,197|199,200|203,205|207,214 ???????S??HHHHHHHHHHHHHHHHHHHSSSSS--EEEHHHHHHHHHHHH-------------------S?TTS?HHH--------HHHHHHHHS??SS?SEEEHHHHHHHHHHSS?GGGHHHHHHHHHHHHHHTTS?B??--SSSTTTTTSS??SS?EEEE?SSSTTEEEEE?SS?-EEEEEE?TTS-?TTS??EE?TT??EES?HHHHHHHS 1Q88|A PF11423.3_Repressor_Mnt_seed 3 30 !Q:0,1 Q:2,29 ??HHHHHHHHHHHHHHHHHHHHHHHHHHHH 1QEY|A PF11424.3_DUF3195_seed 4 90 !Q:6,6|9,9|25,25|28,28|43,43|73,77 Q:0,5|7,8|10,24|26,27|29,42|44,72|78,89 EEEEEE?TT?HHHHHHHHHHHHTTT?TT?EEEEEETTEEEEEE?HHHHHHHHTSHHHHTTEEEEEEESEEESS???-?SSEEEEEETTEE 1RKI|A PF11426.3_Tn7_TnsC_Int_seed 10 49 !Q:0,1|9,9|12,12|21,21|25,26|38,39|45,48 Q:2,8|10,11|13,20|22,24|27,37|40,44 ??GGGGGGS?TT?HHHHHHTS?TTS-?HHHHHHHTTSB??HHHHS???? 1T0F|C PF11427.3_HTH_Tnp_Tc3_1_seed 2 50 !Q:0,0|2,5|20,21|31,32|42,42|48,49 Q:1,1|6,19|22,30|33,41|43,47 ?S????HHHHHHHHHHHHTT??HHHHHHHHT??HHHHHHHHH?STTTT?? 1TC3|C PF11428.3_DUF3196_seed 5 301 !Q:0,10|15,15|18,22|40,40|62,62|76,76|80,80|99,103|108,108|114,115|130,131|143,143|148,148|161,161|165,165|179,179|185,185|208,210|231,231|253,254|257,258|277,279|284,284|297,300 Q:11,14|16,17|23,39|41,61|63,75|77,79|81,98|104,107|109,113|116,129|132,142|144,147|149,160|162,164|166,178|180,184|186,207|211,230|232,252|255,256|259,276|280,283|285,296 ??----?????SSTT?SB?????SSHHHHHHHHHHHHTTT?SSHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHTT?TTS?HHHHHHHHHHHHHHHHHH-----HHHH?GGGGG??HHHHHHHHHTTTTT--TGGGGGGSTTS?TTSS?GGGGGGTHHHHT?TTS?HHHHHHHHHHHTT?GGGTT?EEEEEETTTTEEEEEETTSBSS???HHHHHHHHHHHHHHHHHTSS?HHHHHHHHHHHHHHHHHTTTS??SS-?HHHHHHHHHHHHHHHSSS???TTSH-HHHHHHHHHTTT???? 1TD6|A PF11429.3_Colicin_D_seed 8 95 !Q:7,7|14,19|37,37|40,40|43,44|46,46|52,52|57,57|61,61|67,67|71,71|74,75|80,81|94,95 Q:0,6|8,13|20,36|38,39|41,42|45,45|47,51|53,56|58,60|62,66|68,70|72,73|76,79|82,93 HHHHHGG-GGGGGT??????SHHHHHHHHHHHHHHHH?TT?EE??B?TTSTT?EEEE?TTT?EEEEE?TTS?EE--EEEE??TTSHHHHHHHHH?- 1V74|A PF11430.3_EGL-1_seed 3 21 !Q: Q:0,20 HHHHHHHHHHHHHHHHHHGGG 1TY4|C PF11431.3_Transport_MerF_seed 13 46 !Q:0,3|23,24|44,46 Q:4,22|25,43 ????HHHHHHHHHHHHHHHSSSS??TTHHHHHHHHHHHHHHHHH??- 2H3O|A PF11432.3_DUF3197_seed 3 118 !Q:10,12|15,15|23,24|30,31|38,38|41,45|58,58|77,78|86,86|97,97|109,109|112,113 Q:0,9|13,14|16,22|25,29|32,37|39,40|46,57|59,76|79,85|87,96|98,108|110,111|114,117 HHHHHHHHTT???TT?EEEEEEE??SSTTS??EEEEEE?SS----?EEEEEEEESTTS-TTHHHHHHHHHHHHHHTT??EEEEEEE?GGGHHHHHTS?HHHHHHHHHHH?EE??GGGG 1WNA|A PF11433.3_DUF3198_seed 3 51 !Q:0,1|13,14|33,33|48,50 Q:2,12|15,32|34,47 ??HHHHHHHHHHS??HHHHHHHHHHHHHHHHHH?SHHHHHHHHHHHHH??? 1X9B|A PF11434.3_CHIPS_seed 3 91 !Q:0,1|4,5|22,22|24,24|39,39|48,50|56,56|58,58|61,61|72,73|75,76|81,81|84,85|88,90 Q:2,3|6,21|23,23|25,38|40,47|51,55|57,57|59,60|62,71|74,74|77,80|82,83|86,87 ??SS??BHHHHHHHHHHHHHTT?S?GGGEEEEEEEESTT?EEEEESSS???HHHHT?B?SS?EEEEEEEETT??S??EEEE?TT??SS??? 1XEE|A PF11435.3_She2p_seed 6 214 !Q:30,30|57,58|63,66|69,70|75,75|115,116|121,122|149,154|158,159|169,181|186,192 Q:0,29|31,56|59,62|67,68|71,74|76,114|117,120|123,148|155,157|160,168|182,185|193,213 HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?GGGHHHHHHHHHHHHHHHHHHHHHHH??GGGG????SS??TTTS?BHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHH??GGGS??HHHHHHHHHHHHHHHHHHHHHHHHTT---???GGG??HHHHHHHHT?????????????TTSS???????HHHHHHHHHHHHHHHHHHHHH 1XLY|A PF11436.3_DUF3199_seed 6 136 !Q:0,3|11,13|20,20|41,45|48,57|77,77|80,80|82,82|85,85|88,91|95,96|98,98|102,110|120,120|122,123|128,128 Q:4,10|14,19|21,40|46,47|58,76|78,79|81,81|83,84|86,87|92,94|97,97|99,101|111,119|121,121|124,127|129,135 ????HHHHHHH???HHHHHS?HHHHHHHHHHHHHHHHHHHT?????TT???-----??HHHHHHHHHHHHHHHHTTS?SS?B?SS?SS??--SSS??B?TTS?-???????HHHHGGGSS?S??TTSS?SSHHHHH 1ZTS|A PF11437.3_Vanabin-2_seed 10 117 !Q:4,4|15,15|26,26|31,36|47,47|53,57|66,66|68,71|80,80|85,99|102,102|105,105|116,116 Q:0,3|5,14|16,25|27,30|37,46|48,52|58,65|67,67|72,79|81,84|100,101|103,104|106,115 SSSS?SSTTHHHHHH-HHHHHHHTTT?TTHH------HHHHHHHHHH?HHHHH-----HHHHHHHH-H----HHHHHHHS?SSSS?--------------SS?SS?HHHHHHHHHS? 1VFI|A PF11438.3_N36_seed 2 35 !Q:0,1|20,20|28,31|33,34 Q:2,19|21,27|32,32 ??HHHHHHHTHHHHHHHHHT?GGGSSSS????S?? 1QFQ|B PF11439.3_CesA_seed 2 95 !Q:0,2|47,47|57,58|62,66|86,86|89,89|94,95 Q:3,46|48,56|59,61|67,85|87,88|90,93 ???SSTTTHHHHHHHHHHHHHHHHHHHHHHHHHHTSTTTTTTTHHHH?HHHHHHHTT??SSS?????TTHHHHHHHHHHHHHHHTS?TT?TTTT?- 2LHK|A PF11440.3_AGT_seed 2 355 !Q:18,18|26,26|29,30|37,38|46,46|50,50|61,61|69,70|75,75|90,90|99,102|120,120|127,127|141,156|160,163|165,165|174,176|180,180|189,190|196,196|213,213|219,222|234,236|240,240|243,243|247,249|253,255|260,262|279,283|287,287|290,292|317,317|321,322|328,329|331,331|335,335|352,352 Q:0,17|19,25|27,28|31,36|39,45|47,49|51,60|62,68|71,74|76,89|91,98|103,119|121,126|128,140|157,159|164,164|166,173|177,179|181,188|191,195|197,212|214,218|223,233|237,239|241,242|244,246|250,252|256,259|263,278|284,286|288,289|293,316|318,320|323,327|330,330|332,334|336,351|353,354 SHHHHHHHHHHHHHHHTT?EEEEEEE?SS??GGGGTS??TTTEEEE?TTT?HHHHHHHHTS?SEEEEEE??BTTS?HHHHHHHHHHHHTS?TTSEEEEE????SHHHHTTBSSHHHHHHH?SEEEES?TTSHHHHTHHHHH????????????????EEE????B?HHHHHHHH???GGG?EEEEEEEE??SSGGG?HHHHHHHHHHTTTTTT?EEEEE????STTHHHHHHHT???EEE?TT?GGG???SSS???EEES???HHHHHHHHTTEEEEEE?????GGG?SS???HHHHHHHHHTSEEEEEHHHHHHSB?TTT??BGGGS??S?EEE?GGGHHHHHHHHHHHHT?HH 1Y8Z|A PF11441.3_MxiM_seed 2 115 !Q:0,5|13,13|20,21|24,24|29,29|33,34|39,39|46,46|59,61|64,64|67,67|69,69|86,86|91,92|97,97|113,114 Q:6,12|14,19|22,23|25,28|30,32|35,38|40,45|47,58|62,63|65,66|68,68|70,85|87,90|93,96|98,112 ??????EEEEEEE?SGGGTT??TT?EEEE?TTT??EEEE?SSEEEE?EEEEETTEEEEE???EE?TT?S?HHHHHHHHHHHHHHHH?EEEE??SSSS?EEEEETTEEEEEEEE?? 1Y9L|A PF11447.3_DUF3201_seed 4 156 !Q:22,23|28,30|34,34|36,36|47,48|50,50|80,81|92,92|95,95|102,102|106,106|111,112|116,118|131,131|140,140|143,143|154,154 Q:0,21|24,27|31,33|35,35|37,46|49,49|51,79|82,91|93,94|96,101|103,105|107,110|113,115|119,130|132,139|141,142|144,153|155,155 HHHHHHHHHHHHHHHHHHHHST--TSEE???EEE?S?EEEETTEEEE??S?EEEEEEETTEEEEEETTEEEEEEEEEGGG??HHHHHHHHHH?SE-EEEESS?TTT?EEEE--TTS???HHHHHHHHHTSS?SEEEEEEE?TT?HHHHHHHHHH-H 1YB3|A PF11458.3_Mistic_seed 3 85 !Q:2,2|4,4|28,29|33,33|36,36|39,39|60,60|74,74|79,79 Q:0,1|3,3|5,27|30,32|34,35|37,38|40,59|61,73|75,78|80,84 TT?S?SHHHHHHHHHHTTTHHHHHHHHH??SSS?SS?SS?SHHHHHHHHHHHHHHTSSSS?HHHHHHHHHHHHH-TTTS?SSTTT 1YGM|A PF11461.3_RILP_seed 14 69 !Q:0,1|37,44|51,54 Q:2,36|45,50|55,68 ??TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSTT??-----?HHHHHH----HHHHHHHHHHHHHH 1YHN|B PF11462.3_DUF3203_seed 5 77 !Q:0,1|7,9|17,17|21,24|48,49|52,53|65,65|67,68|71,76 Q:2,6|10,16|18,20|25,47|50,51|54,64|66,66|69,70 ??EEEET---TTTEEEE?SSS????EEGGGEEEEEETTTTEEEEEETT??EE??HHHHHHHHHTT?B??SS?????? 1YWY|A PF11463.3_R-HINP1I_seed 3 210 !Q:2,3|15,15|18,18|21,21|32,34|37,37|48,48|52,53|60,60|69,71|86,87|91,92|94,95|98,100|105,105|130,130|136,137|164,164|166,166|168,168|172,172|176,176|187,189|193,193|204,204 Q:0,1|4,14|16,17|19,20|22,31|35,36|38,47|49,51|54,59|61,68|72,85|88,90|93,93|96,97|101,104|106,129|131,135|138,163|165,165|167,167|169,171|173,175|177,186|190,192|194,203|205,209 TT??TTTEEEEEEEE?SS-SS?SEEEEEEESS?--SS?EEEEEEEEEE?SSS??EEEEEE?HHHHHHHH???HHHHHHHHHHHTSS??SSS??S-?SS???GGGS?HHHHHHHHHHHHHTHHHHHHHHHT?SSTTS??EEEEEEEETTEEEEEEEEHHHHHHHH-T?S?EEE?TTS?EEETTEEEEE???GGG?GGGGSEEEEE?GGGGG 2FKH|B PF11464.3_Rbsn_seed 6 42 !Q:19,19|41,41 Q:0,18|20,40 HHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHH? 3V1F|A PF11465.3_Receptor_2B4_seed 4 109 !Q:0,2|10,10|14,14|18,19|22,24|27,27|35,35|40,40|44,44|53,54|67,67|71,72|78,79|83,83|92,92|95,95|107,108 Q:3,9|11,13|15,17|20,21|25,26|28,34|36,39|41,43|45,52|55,66|68,70|73,77|80,82|84,91|93,94|96,106 ???EEEEEEE?TTS?EEE??SS???TT?EEEEEEE?TTSS?EEE-EEEESSSS??BSSGGGGGTEEE?TTT??EEESS??GGG?EEEEEEEE?TT?BEEEEEEEEEE?? 1RZJ|C PF11466.3_Doppel_seed 7 30 !Q:0,4|26,29 Q:5,25 ?????SSTTHHHHHHHHHHHHHTTTS???? 1Z65|A PF11467.3_LEDGF_seed 9 125 !Q:15,15|19,20|35,37|57,57|60,78|98,124 Q:0,14|16,18|21,34|38,56|58,59|79,97 HHHHHHHHHHHHHHT?GGG??HHHHHHHHHHHHHS???HHHHGGGHHHHHHHHHHTT?TT?------------------SSHHHHHHHHHHHHHHHHH??????????????????????????? 3F9K|C PF11468.3_PTase_Orf2_seed 12 320 !Q:18,21|37,37|41,42|49,49|51,51|56,57|64,64|68,69|81,84|100,102|122,123|127,129|140,140|155,158|176,178|180,181|199,203|205,208|217,222|233,233|236,237|247,250|253,258|273,274|276,276|280,282|304,305|316,319 Q:0,17|22,36|38,40|43,48|50,50|52,55|58,63|65,67|70,80|85,99|103,121|124,126|130,139|141,154|159,175|179,179|182,198|204,204|209,216|223,232|234,235|238,246|251,252|259,272|275,275|277,279|283,303|306,315 HHHHHHHHHHHHHHHHHT????HHHHHHHHHHTGGGG?SSS??EEEEEE?G-GGTT??EEEEEE?GGG??HHHHHHHHTSS-???SSTHHHHHHHHHHHS?-?SEEEEEEETTTEEEEEEEE??GGG???HHHHHTSTTS?HHHHHTHHHHHHTT?-??EEEEEEETTTTEEEEEE--?S??TTTTSHHHHHHHHHHHT?????H----HHHHHHHT-----?SEEEEEEESS?SS??EEEEEEEES---?TT??????HHHHHHHHHHHHHS??S?TTS???EEEEEEEETTEEEEEEEEEEE??HHHHHHHHHH???? 2XM5|A PF11469.3_Ribonucleas_3_2_seed 3 120 !Q:25,31|48,50|56,56|75,75|87,88|93,93 Q:0,24|32,47|51,55|57,74|76,86|89,92|94,119 HHHHHHHHHHHHHHHHHHHHHHHTS???????HHHHHHHHHHHTGGGG??-GGGTT?HHHHHHHHHHHHHHTTSS?HHHHHHHHHTT??GGGG?TTTHHHHHHHHHHHHHHHHHHHHHTT 1ZTD|A PF11470.3_TUG-UBL1_seed 28 75 !Q:2,2|6,6|11,13|31,32|35,39|41,41|48,48|51,54|59,59|65,67|70,70 Q:0,1|3,5|7,10|14,30|33,34|40,40|42,47|49,50|55,58|60,64|68,69|71,74 EE?TTS?EEEE???TTSBHHHHHHHHHHHTT??GG-----G?EEEETT-EE----ESSS?BHHHH???SS?EEEE 2AL3|A PF11472.3_DUF3206_seed 2 128 !Q:1,8|32,34|37,38|48,48|70,70|73,73|97,99|120,120 Q:0,0|9,31|35,36|39,47|49,69|71,72|74,96|100,119|121,127 S????????GGGHHHHHHHHHHHHHHHHHHHH???TT??HHHHHHHHH?TTHHHHHHHHHHHHHHHHHTT?TT?SSHHHHHHHHHHHHHHHHHHHTT???HHHHHHHHHHHHHHHHHHHT?HHHHHHH 2AU5|A PF11473.3_B2_seed 2 73 !Q:0,2|24,26|30,30|61,61|70,72 Q:3,23|27,29|31,60|62,69 ???HHHHHHTHHHHHHHHHTTGGG???TTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?HHHHHHTT??? 2AZ2|A PF11474.3_N-Term_TEN_seed 2 188 !Q:0,10|12,12|23,23|26,27|43,43|46,49|59,59|66,67|72,84|99,101|108,108|117,124|140,140|151,151|169,169|179,180|182,183|187,187 Q:11,11|13,22|24,25|28,42|44,45|50,58|60,65|68,71|85,98|102,107|109,116|125,139|141,150|152,168|170,178|181,181|184,186 ???????????B?HHHHHHHHHH?TT??EEEEHHHHHHHTTSS?TT????HHHHHHHHH?EEEESS??TGGG?????????????HHHHHHHHHHHTTT???BGGGTT?EEETTEEE????????TTTTSHHHHHHHHHH?HHHHHHHHHH?EEEEEEETTEEEEEESB?HHHHHHHHS??S??SEE? 2B2A|A PF11475.3_VP_N-CPKC_seed 5 32 !Q:0,1|3,5|7,9|14,14|23,23|29,31 Q:2,2|6,6|10,13|15,22|24,28 ??S???S???SSSS?GGGHHHHH?SSSTT??? 2BAI|A PF11476.3_TgMIC1_seed 2 137 !Q:0,3|13,13|16,16|24,24|31,31|35,35|56,56|60,63|75,75|79,79|105,106|116,117|120,120|130,131|136,136 Q:4,12|14,15|17,23|25,30|32,34|36,55|57,59|64,74|76,78|80,104|107,115|118,119|121,129|132,135 ????SSSEEEEEE?SS?EEEEEEE?SEEEEE?TTT?EEEEETTTTEEEEESSSSSS?EEE????EEEEEEEEEEE?SSS?EEEEEEEEETTSSEEEEEEEESSSS??SSEEEEEES??TT?EEEEEBTTB??STTT? 2K2S|A PF11477.3_PM0188_seed 4 392 !Q:25,25|27,27|30,30|38,41|48,49|55,56|63,63|71,71|75,75|77,80|106,106|119,120|131,131|136,136|141,142|157,161|163,163|170,170|176,176|183,183|190,190|207,208|210,210|216,216|229,230|234,235|244,244|250,254|258,260|283,287|290,290|296,297|317,318|322,322|331,333|340,341|348,348|358,360|363,363|374,377|389,389 Q:0,24|26,26|28,29|31,37|42,47|50,54|57,62|64,70|72,74|76,76|81,105|107,118|121,130|132,135|137,140|143,156|162,162|164,169|171,175|177,182|184,189|191,206|209,209|211,215|217,228|231,233|236,243|245,249|255,257|261,282|288,289|291,295|298,316|319,321|323,330|334,339|342,347|349,357|361,362|364,373|378,388|390,391 EEEEEEESSSHHHHHHHHHHHHTTT?S-SS?EEEEETT????HHHHTT?-SSEEE??BSSSSB?THHHHHH-HTS?S?---EEEEEEEESTTHHHHHHHHHHHHTT?TTTEEEEEEEEE??STHHHHHHHT-TTTS?HHHH--HHHHHHHHHHHHHH?????S?HHHHTT?GGGTS?EEEEES?HHHHHH?GGGHHHHHHHGGGEEE??S?TGGGS?HHHHHHHHHHTT??HHH--HHHTTSSS?EEEEE?????SSS???HHHHHHHHHHHHHHHHSTTSTT???--TT?EEEEE??GGGTHHHHHHHHHSSSEEE??TTS?HHHHHHTT???SEEEEE??GGGGGS?GGGEEEEEE???SS?SSHHHHHTSH----HHHHHHHHTSS?GG 2C84|A PF11478.3_Tachystatin_B_seed 2 42 !Q:0,3|5,5|8,8|14,14|17,17|19,19|31,31|39,41 Q:4,4|6,7|9,13|15,16|18,18|20,30|32,38 ????B?SS?EEETT?SS?B?TTEEEEESSTT?SEEEEEE??? 2DCV|A PF11479.3_Suppressor_P21_seed 2 177 !Q:0,5|8,8|26,27|31,31|62,76|92,94|97,98|117,119|146,148|160,161|173,176 Q:6,7|9,25|28,30|32,61|77,91|95,96|99,116|120,145|149,159|162,172 ??????SS?HHHHHHHHHHHHHHHTT??TTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHT???????????????HHHHHHHHHHHHTTT???TT??SSHHHHHHHHHHHHHHHH???HHHHHHSBHHHHHHHHHHHHHHHHTS???GGGSTTHHHHH??SBHHHHHHHTT???? 2CWO|A PF11480.3_ImmE5_seed 5 86 !Q:0,1|3,3|19,20|30,30|33,35|39,39|43,43|46,50|53,53|76,77|84,85 Q:2,2|4,18|21,29|31,32|36,38|40,42|44,45|51,52|54,75|78,83 ??B?HHHHHHHHHHHHHHT??EEEEEEEEE?SS--?EEE?GGG?EE-????SS?GGGHHHHHHHHHHHHHHHHHTT??EEEEEE?? 2FHZ|A PF11482.3_DUF3208_seed 4 118 !Q:0,0|17,19|25,25|30,39|49,50|55,55|59,59|77,78|80,81|103,103|114,117 Q:1,16|20,24|26,29|40,48|51,54|56,58|60,76|79,79|82,102|104,113 ?EEEEEEEEEEEEETTS???HHHHS?SEET----------TEEEEEEEE??SSSB?TTS?BGGGEEEEEEEEEEEES??H--HHHHHHHHHHHHHHHHHHHTS?TTSEEEEGGG???? 2EBE|A PF11483.3_DUF3209_seed 5 125 !Q:0,2|17,17|19,20|38,38|47,48|68,68|72,72|75,75|77,79|120,124 Q:3,16|18,18|21,37|39,46|49,67|69,71|73,74|76,76|80,119 ???HHHHHHHHHHHHHT-T??GGGGHHHHHHHTTTTTT?HHHHHHHH??SHHHHHHHHHHHHHHHHHH-HHH?TT?H---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH????? 2EHW|A PF11485.3_DUF3211_seed 11 161 !Q:0,2|9,9|12,12|22,22|39,40|51,54|79,99|125,125|160,160 Q:3,8|10,11|13,21|23,38|41,50|55,78|100,124|126,159 ???EEEEEE?SS?HHHHHHHHT?HHHHHHHHSTTEEEEE??STTEEEEEEE----ETTEEEEEEEEEEEETTEEEEEEE---------------------ETTEEEEEEEEEEETTEEEEEEEES?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT? 2EJX|A PF11486.3_DUF3212_seed 4 122 !Q:0,4|29,31|44,46|56,57|59,60|63,64|84,85|101,121 Q:5,28|32,43|47,55|58,58|61,62|65,83|86,100 ?????HHHHHHHHHHHHHHHHHHHHHBSS???HHHHHHHHHHTT???HHHHHHHHH??S??SS-?SSSHHHHHHHHHHHHHGGG??HHHHHHHHHHHHHHT????????????????????? 2EUC|A PF11487.3_RestrictionSfiI_seed 2 263 !Q:0,1|3,3|8,8|42,43|47,48|65,66|69,69|71,74|77,77|86,87|90,91|105,105|108,108|110,110|113,113|117,118|120,120|125,125|129,129|135,137|139,139|146,146|168,174|187,188|196,196|202,202|207,207|210,210|215,218|222,222|230,230|239,240|243,243|246,248|254,254|258,258 Q:2,2|4,7|9,41|44,46|49,64|67,68|70,70|75,76|78,85|88,89|92,104|106,107|109,109|111,112|114,116|119,119|121,124|126,128|130,134|138,138|140,145|147,167|175,186|189,195|197,201|203,206|208,209|211,214|219,221|223,229|231,238|241,242|244,245|249,253|255,257|259,262 ??S?GGGS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS??SSS??HHHHHHHHHHHHHTTS??SB?S????SS?SEEEEEEE??TT??EEEEEEEEEEEES?SS?E-EE?GGG??S?EEEE?TTT?SEEEE???S?SEEEEE?SSSSEEEEEEEEEEEEEEEEE???????SEEEEEEEEEEE??GGGHHHH?SBTTB?SEEE?SS?TTTT????EEE?HHHHHHH?GGGEEEEE??TT?SS???EEEEE?TTS?EEEE 2EZV|A PF11491.3_DUF3213_seed 2 90 !Q:0,0|4,6|8,8|27,32|37,38|42,43|45,45|47,47|53,55|62,62|65,71|74,89 Q:1,3|7,7|9,26|33,36|39,41|44,44|46,46|48,52|56,61|63,64|72,73 ?EEE???S?TTTTTHHHHHTTTTTTTB??????TTTT??EEE??B?S?SHHHH---HHHTTT?SS???????SS???????????????? 2F40|A PF11492.3_Dicistro_VP4_seed 11 64 !Q:0,0|11,11|15,16|18,21|25,27|30,35|37,38|43,47|50,53|63,63 Q:1,10|12,14|17,17|22,24|28,29|36,36|39,42|48,49|54,62 ?HHHHHHHHHT-TSS??S????GGG???TT--????S??SSSS----?TT????HHHHHHHTT? 1B35|D PF11493.3_TSP9_seed 5 86 !Q:0,13|25,28|30,31|33,34|38,38|40,45|47,53|55,55|57,57|59,60|65,65|67,67|70,70|72,73|75,76|78,78|84,85 Q:14,24|29,29|32,32|35,37|39,39|46,46|54,54|56,56|58,58|61,64|66,66|68,69|71,71|74,74|77,77|79,83 ????-?????????SHHHHHHHHHS????S??S??SSS?S????-?S???????S?S?S??SSSS-S?SS?S??S??S-SSSSS?? 2FFT|A PF11494.3_Ta0938_seed 4 109 !Q:0,2|7,7|11,13|19,19|22,24|26,28|31,31|33,33|36,37|42,43|48,48|52,52|66,68|71,73|77,77|79,80|85,89|92,92|95,99|108,108 Q:3,6|8,10|14,18|20,21|25,25|29,30|32,32|34,35|38,41|44,47|49,51|53,65|69,70|74,76|78,78|81,84|90,91|93,94|100,107 ???EEEE?SSS???SGGGS?SS???S???SS?B?TT??BSSS??SSSS?TTS?THHHHHHHHHHHS???EE???TTT?S??EEEE?????TT?SS?????HHHHHTTT? 2FQH|A PF11495.3_Regulator_TrmB_seed 30 267 !Q:0,0|21,21|30,30|49,49|58,66|80,80|82,84|86,87|90,93|105,105|109,110|113,115|120,121|136,143|147,147|153,154|158,158|161,161|166,166|179,179|183,183|195,195|197,198|207,208|213,223|230,230|242,242|248,248|251,252|266,266 Q:1,20|22,29|31,48|50,57|67,79|81,81|85,85|88,89|94,104|106,108|111,112|116,119|122,135|144,146|148,152|155,157|159,160|162,165|167,178|180,182|184,194|196,196|199,206|209,212|224,229|231,241|243,247|249,250|253,265 ?EEEESSHHHHHHHHHHHHHH?SSEEEEEE?HHHHHHHHHHHHHHHHTT?EEEEEESS-----????GGGSSSSEEEEEE?S???S--EE----EEETTTEEEEE?SSS??SS???EEEE??HHHHHHHHHHHHHH--------HHH?EEEEE--EES?TT?EEES?HHHHHHHHHHHT-TTS?EEEEEEEEETT-T??EEEEEEEE--EEEE-----------EETTTT-EEEEEEEETTE-EEEEE?TT??SSSEEEEEEEEEE? 3QPH|A PF11496.3_HDA2-3_seed 26 536 !Q:0,2|10,12|34,34|36,38|44,45|50,80|96,96|98,98|101,101|103,104|107,108|110,110|112,120|132,132|146,159|164,185|193,193|208,212|223,224|226,227|229,231|233,329|340,342|345,346|349,350|353,353|355,355|362,362|365,367|378,442|444,445|467,468|471,471|483,502|511,513|516,518|527,527 Q:3,9|13,33|35,35|39,43|46,49|81,95|97,97|99,100|102,102|105,106|109,109|111,111|121,131|133,145|160,163|186,192|194,207|213,222|225,225|228,228|232,232|330,339|343,344|347,348|351,352|354,354|356,361|363,364|368,377|443,443|446,466|469,470|472,482|503,510|514,515|519,526|528,535 ???SEEEEEE???HHHHHHHHHHHHHTHHHHHHH-H---HSTTT??HHHH-------------------------------HHHHHHHHHHHHHHH?G-GG-T??TT??S?S--------?STTHHHHHHTT?HHHHHHHHHHHHH--------------TTSS----------------------EEEEEEE?STHHHHHHHHHHTT-----SSSEEEESSS??S??S???S?-----------------------------------------------------------------------------------------------?SEEEEEEESS???TT--TS??TT?S?EEEEEE?SS???TTSHHHHHHH??????----------------------------------------------??-?-------??S??EEEEEETTSHHHHHHHHTTTT?-TT?HHHHHHHHHHH--------------------HHHTTTTT???TT---THHHHHTT-TGGGHHHH 3MWY|W PF11497.3_NADH_Oxid_Nqo15_seed 3 131 !Q:0,3|28,29|36,36|42,43|46,49|51,51|60,60|64,64|72,73|79,80|86,87|111,112|128,130 Q:4,27|30,35|37,41|44,45|50,50|52,59|61,63|65,71|74,78|81,85|88,110|113,127 ????HHHHHHHHHHHHHHHHHHHHHHTT??EEEEEE?HHHHS??SS????S?SEEEEEEE?SSS?EEEEEEE??SSSSS??EEEEE--TTTTEEEEEEEETTTEEEETTEE??HHHHHHHHHHHHHHH??? 3I9V|7 PF11501.3_Nsp1_seed 3 115 !Q:0,0|8,9|13,13|15,17|19,19|37,37|42,44|52,52|54,54|60,61|64,68|71,73|81,81|90,91|97,98|100,102|111,114 Q:1,7|10,12|14,14|18,18|20,36|38,41|45,51|53,53|55,59|62,63|69,70|74,80|82,89|92,96|99,99|103,110 ?EEEEEEE??TTT?S???S?SSHHHHHHHHHHHHHHT?EEEE???TTSGGGS?S?EEEEE??SS?????SS???EEEEESS?TTTTSSSS??EEEEE??S???SEEEEEEE???? 2HSX|A PF11502.3_BCL9_seed 7 41 !Q:0,2|24,40 Q:3,23 ???HHHHHHHHHHHHHHHHHHHHH???-????????????? 2GL7|C PF11503.3_DUF3215_seed 4 94 !Q:9,9|16,16|20,20|32,33|47,47|57,57|60,60|78,80|82,93 Q:0,8|10,15|17,19|21,31|34,46|48,56|58,59|61,77|81,81 EEHHHHHHH?SEEEEE?TTS?EEEEEEGGGTS??TTHHHHHHHHHHH?SSEEEEEEE?SS?EEEEEEETTEEEEEEES???S???????????? 2GRG|A PF11504.3_Colicin_Ia_seed 3 72 !Q:10,10|15,15|26,27|29,29|33,33|45,46|57,57|67,70 Q:0,9|11,14|16,25|28,28|30,32|34,44|47,56|58,66|71,71 HSSHHHHHHH?TTTS?EEEEEEEEEE??S?TTT?SEEEEEEEEEE??HHHHHHHHTS?HHHHHHHTS????S 2HDI|B PF11505.3_DUF3216_seed 2 97 !Q:15,15|37,37|60,62|81,97 Q:0,14|16,36|38,59|63,80 HHHHHHHHHHHHTTT?HHHHHHHHHHHHTTSHHHHHH?HHHHHHHHHHHHHHHHHHHTTT???HHHHHHHHHHHHHHHHHH????????????????- 2HJM|A PF11506.3_DUF3217_seed 2 104 !Q:0,1|16,16|19,19|60,60|90,91|94,103 Q:2,15|17,18|20,59|61,89|92,93 ??EEEEEEEEEEEEEE?TT?SEEEEEEEEEEEETTEEEEEEEEEEEEHHHHHHHHHHHTT?SEEEEEEEEEEEEETTTTEEEEEEEEEEE??TT?????????? 2HQL|A PF11507.3_Transcript_VP30_seed 3 131 !Q:0,1|15,17|20,21|40,40|57,58|75,76|89,89|108,108|110,112|123,130 Q:2,14|18,19|22,39|41,56|59,74|77,88|90,107|109,109|113,122 ??HHHHHHHHHHHHT???TT??HHHHHHHHHHHHHHHTTS?GGGHHHHHHHHHHHHT??GGGHHHHHHHHHHHHT??TTHHHHHHHHHS?HHHHHHHHHHHHHHGGGS?S???HHHHHHHHTT???????? 2I8B|A PF11508.3_DUF3218_seed 2 213 !Q:0,2|6,6|23,23|27,29|44,44|52,52|56,57|109,109|119,119|121,121|126,126|130,132|137,137|141,141|154,155|162,165|178,178|196,197 Q:3,5|7,22|24,26|30,43|45,51|53,55|58,108|110,118|120,120|122,125|127,129|133,136|138,140|142,153|156,161|166,177|179,195|198,212 ???TTT?HHHHHHHHHHHHHHHH?TTS???HHHHHHHHHHHHHH?GGGSGGG?GGG??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHHH?TTGGGGGTT?S?SSTT?EEE???TTSS?STT?BEEETTTEESSS??HHHHHH????HHHHHHHGGGTT?BTTSTTHHHHHHHHHHH??HHHHHHHHHHHHTTT 2IGS|A PF11510.3_FA_FANCE_seed 2 267 !Q:0,12|31,41|50,51|67,68|82,82|85,87|106,106|109,111|143,144|157,157|161,161|176,178|192,196|209,216|235,236|248,248|266,266 Q:13,30|42,49|52,66|69,81|83,84|88,105|107,108|112,142|145,156|158,160|162,175|179,191|197,208|217,234|237,247|249,265 ?----????????HHHHHHHHHHHHHHHHHH???????????HHHHGGGG??HHHHHHHHHHHTGGG??HHHHHHHHHHHHH?SS???HHHHHHHHHHHHHHHHHH?SS???HHHHHHHHHHHHHSHHHHHHHHHHHHHHSTT??HHHHHHHHHHHH?TTS?HHHHHHHHHHHHHS???HHHHHHHHHHHTT?????HHHHHHHHHHHH????????SHHHHHHHHHHHHHTGGG??HHHHHHHHHHH?SSSSSSHHHHHHHHHHH? 2ILR|A PF11511.3_RhodobacterPufX_seed 5 69 !Q:8,12|59,60|66,66 Q:0,7|13,58|61,65|67,68 SSGGGSSS??--?HHHHHHHHHHHHHTHHHHTHHHHHHHHHHHHHHHHHHHHSSTTTTT??SSSSS?SS 2NRG|A PF11512.3_Atu4866_seed 14 79 !Q:0,6|11,11|52,52|56,56|58,59|62,63|78,78 Q:7,10|12,51|53,55|57,57|60,61|64,77 -??????EEEE?SSSSEEEEEETTTEEEEEETTEEEEEEEEEEEETTEEEEB?TTS?B??EE??SSSEEEETTEEEEE? 2JMB|A PF11513.3_TA0956_seed 3 114 !Q:0,1|14,15|38,40|44,44|53,59|82,82|84,85|89,91|107,107|113,113 Q:2,13|16,37|41,43|45,52|60,81|83,83|86,88|92,106|108,112 ??EEEEEEEESSSS??EEEEEEHHHHHHHHHHHHHHTT???HHH-HHHHHHHH???????TTSEEEEEEEEETTTTEEEEEE?S??HHH---HHHHHHHHHHHHTTS?EEEEE? 2K24|A PF11514.3_DUF3219_seed 2 99 !Q:1,1|10,11|18,21|25,25|28,29|36,36|46,46|49,49|51,51|67,68|70,70|73,74|76,77|79,79|92,94|96,96|98,98 Q:0,0|2,9|12,17|22,24|26,27|30,35|37,45|47,48|50,50|52,66|69,69|71,72|75,75|78,78|80,91|95,95|97,97 T?EEETTEEE??SEEEEE?---SSS?EE--EEEEEE?TTTHHHHTT?BS?S?EEEEETTTTEEEEEB??S?SS??B??S?EEEEEEEEEEEB???S?S? 2JN9|A PF11515.3_Cul7_seed 8 79 !Q:17,18|21,21|26,26|28,28|33,33|36,36|40,40|45,45|51,52|74,78 Q:0,16|19,20|22,25|27,27|29,32|34,35|37,39|41,44|46,50|53,73 GGGSSSSHHHHHHHHHH??TT?EEEE?S?BTTB?TT?EEE-EEEE?TTSSE--EEEEETTTTEEEEEEGGGEEE????? 2JUF|A PF11516.3_DUF3220_seed 2 106 !Q:0,2|4,7|9,11|16,17|20,21|29,29|46,46|73,73|77,77|102,105 Q:3,3|8,8|12,15|18,19|22,28|30,45|47,72|74,76|78,101 ???S????S???TTTS??TT??SSSSSSS?HHHHHHHHHHHHHHHH?HHHHHHHHHTTTHHHHHHHHHHGGGT?SSS?STTTTTTSSSHHHHHHHHTTGGGG???? 2JPF|A PF11517.3_Nab2_seed 4 110 !Q:0,7|25,26|28,28|44,45|57,57|61,61|83,84|94,96|102,109 Q:8,24|27,27|29,43|46,56|58,60|62,82|85,93|97,101 ??--????HHHHHHHHHHHHTTSTT??S?HHHHHHHHHHHHHTT??HHHHHHHHHHH?TTS?HHHHHHHHHHHHHHHHHHHTT??HHHHHHHHH---HHHHT???????? 3LCN|A PF11518.3_DUF3221_seed 9 116 !Q:0,10|12,13|15,15|17,17|19,21|23,24|35,35|43,43|46,49|51,51|57,57|73,75|77,77|80,80|86,87|101,101|105,105|115,115 Q:11,11|14,14|16,16|18,18|22,22|25,34|36,42|44,45|50,50|52,56|58,72|76,76|78,79|81,85|88,100|102,104|106,114 ?---------?S??S?S?S---S??EEEEEEEEEE?SSEEEEE?SS????T-TGGGS?HHHHHHHSTTTEEEE---E?TT?TTGGG??TTEEEEEEEEEEE?SSS?EEEEEEEEE? 2JQO|A PF11519.3_DUF3222_seed 3 75 !Q:25,25|29,29|39,39|45,47|50,53|67,67|70,74 Q:0,24|26,28|30,38|40,44|48,49|54,66|68,69 TTTHHHHHHHHHHHHHHHTSEEEEE?SSS?EEEEETTSS?EEETT???SS????TTSTHHHHHHHHH?SS????? 2JS3|A PF11520.3_Cren7_seed 7 65 !Q:0,7|9,11|16,16|18,18|21,21|26,27|34,35|39,40|48,48|52,53|59,60|63,64 Q:8,8|12,15|17,17|19,20|22,25|28,33|36,38|41,47|49,51|54,58|61,62 ??---???S--?EEEE?T-TS?EEEE??SEEEEE??TTS??EEEEEEE?TTT??EEEEE??TT?? 3LWH|A PF11521.3_TFIIE-A_C-term_seed 8 96 !Q:0,50|67,67|75,75|93,96 Q:51,66|68,74|76,92 ?????????????-????????---------????????????????????EEEETTEEEEHHHHHH?HHHHHHS?HHHHHHHHHHHHHHTSS???- 2JTX|A PF11522.3_Pik1_seed 20 68 !Q:0,1|15,16|19,19|22,43|46,47|50,50|66,67 Q:2,14|17,18|20,21|44,45|48,49|51,65 ??TTHHHHHHHHHHT??SS?SS?------------------???TT??SS?SHHHHHHHHHHHHHT?? 2JU0|B PF11523.3_DUF3223_seed 30 99 !Q:6,7|10,10|15,18|22,22|35,39|48,49|51,51|63,70|79,80|83,83|85,89|92,93 Q:0,5|8,9|11,14|19,21|23,34|40,47|50,50|52,62|71,78|81,82|84,84|90,91|94,98 HHHHHH--HS?TTEE??--HHH-HHHHHHHHHTST-----THHHHHTT?-E-EEEEEEESSSS-------?EEEEEEET--TS?E-----EE??GGGSS 2K0M|A PF11524.3_SeleniumBinding_seed 3 87 !Q:0,2|12,14|18,19|26,29|31,32|50,51|55,64|67,67|69,72|78,79|83,86 Q:3,11|15,17|20,25|30,30|33,49|52,54|65,66|68,68|73,77|80,82 ???SSSSEEESS???TTS??EEEEEE????S--SHHHHHHHHHHHHHHTT??EEE??????---?SS-S????EEEEE??SSS???? 2JZ7|A PF11525.3_CopK_seed 5 74 !Q:0,4|15,15|24,24|29,29|32,33|36,38|41,42|49,49|62,73 Q:5,14|16,23|25,28|30,31|34,35|39,40|43,48|50,61 ?????EEEEEEBTTS?EEEEETTS?EEEE?TT??EE???SS??EEBTTS?EEEEETTEEEEE???????????? 3N7D|A PF11526.3_CFIA_Pcf11_seed 10 113 !Q:0,22|24,24|26,30|37,38|43,112 Q:23,23|25,25|31,36|39,42 ???????????????????????B?B?????HHHHHH??TTTT????????????????????----?????????????????????????????????????????????? 2NPI|C PF11527.3_ARL2_Bind_BART_seed 32 158 !Q:2,2|18,18|21,21|35,36|40,41|43,45|47,47|74,79|81,82|86,87|94,118|121,121|138,138|156,157 Q:0,1|3,17|19,20|22,34|37,39|42,42|46,46|48,73|80,80|83,85|88,93|119,120|122,137|139,155 SS?HHHHHHHHHHHHHTS?HH-HHHHHHHHHHHHH--HTT??S---S?SSTTHHHHHHHHHHHHHHHHHHHHHT------T??SSS??THHHHH-------------------------SS?GGGSSHHHHHHHHGGG?HHHHHHHHHHHHHHHHT?? 3DOE|B PF11528.3_DUF3224_seed 11 148 !Q:0,2|18,19|25,25|29,29|41,42|58,63|66,66|108,108|110,110|113,114|130,130|132,132|136,136|138,138|147,147 Q:3,17|20,24|26,28|30,40|43,57|64,65|67,107|109,109|111,112|115,129|131,131|133,135|137,137|139,146 ???EEEEEEEEEEEEEEE--EEEEE?TTS?EEEEEEEEEEE-?SSEEEEEEEEEEEEE------EE-TTEEEEEEEEEEEEEETTEEEEEEEEEEEEEETTEEEEEEE-E?TT??EETTTTEEEEEEEEE?S-TTE-E-EEEEEEEE? 2Q03|A PF11529.3_AvrL567-A_seed 3 127 !Q:0,14|23,23|40,41|48,48|50,52|55,56|63,64|69,69|73,73|83,84|87,87|89,90|92,93|98,99|101,102|106,106|108,109|115,116|125,126 Q:15,22|24,39|42,47|49,49|53,54|57,62|65,68|70,72|74,82|85,86|88,88|91,91|94,97|100,100|103,105|107,107|110,114|117,124 ???????????????EEEESSTT?EEEETTTEEEEESSTT??SEEEEE?S???SS??EEEEEE??SSSS?TTS?EEEEEEETT??SS?B??B??STTS??S??GGG?B??SSTTS??EEEEEEEE?? 2OPC|A PF11530.3_Pilin_PilX_seed 2 127 !Q:0,1|28,28|31,32|47,50|79,79|83,86|94,95|109,110|121,126 Q:2,27|29,30|33,46|51,78|80,82|87,93|96,108|111,120 ??HHHHHHHHHHHHHHHHHHHHHHHHHH?TT??HHHHHHHHHHHHHH????HHHHTTEEEEEEESSTTSTTSEEEEEEE?TTS????EEEEETT??EEEESSHHHHHHT??SEETTEEEEE?????? 2OPD|A PF11531.3_CARM1_seed 3 117 !Q:0,6|19,19|24,24|40,40|50,50|53,54|88,88|107,116 Q:7,18|20,23|25,39|41,49|51,52|55,87|89,106 ?---???EEEEEEEEEEEE?TTSS?EEEEEEEEEEEEEEE?SSEEEEEEE?TT??EEEEEEEETTSEEEEETTTEEEEEETTEEEEEE?SSHHHHHHHHHHHHHHTT?????????? 2OQB|A PF11532.3_HnRNP_M_seed 3 31 !Q:0,22|25,30 Q:23,24 ????????????????-??????SS?????? 2OT8|C PF11533.3_DUF3225_seed 24 131 !Q:3,4|26,26|35,36|40,40|63,64|67,69|92,94|97,99|101,101|112,112|115,115|127,130 Q:0,2|5,25|27,34|37,39|41,62|65,66|70,91|95,96|100,100|102,111|113,114|116,126 GGB??HHHHHHHHHHHHHHHHHHHTT?HHHHHHHB??STT?EEEETTEEEESHHHHHHHHHHS??TT???EEEEEEEEEBTTSEEEEEEEEE?--SS??-S?EEEEEEEEEE-TT-EEEEEEEEEEE?-?? 2RCD|A PF11534.3_HTHP_seed 9 75 !Q:0,7|9,10|32,34|48,48|73,74 Q:8,8|11,31|35,47|49,72 ????????S??SSHHHHHHHHHHHHHHHHHHH???HHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHTTT?? 2OYY|A PF11535.3_Calci_bind_CcbP_seed 17 131 !Q:10,19|36,37|45,48|50,54|57,61|70,71|79,79|85,85|90,90|92,92|106,107|113,120 Q:0,9|20,35|38,44|49,49|55,56|62,69|72,78|80,84|86,89|91,91|93,105|108,112|121,130 HHHHHHTSTT??--------SHHHHHHHHHHHHHHH??SSEEEEE????S-----TT?????EEEEEEEE??TTTTTSS?EEEEE?TTTT?S?EEEEEGGGEEEES??HHHHH--------HHHHHHHHHH 2P0P|A PF11536.3_DUF3226_seed 4 249 !Q:5,5|23,24|27,28|30,35|40,42|45,49|63,63|65,66|85,88|103,103|112,112|115,119|130,131|141,142|144,150|154,158|177,177|191,191|193,193|207,208|227,227|240,240|248,248 Q:0,4|6,22|25,26|29,29|36,39|43,44|50,62|64,64|67,84|89,102|104,111|113,114|120,129|132,140|143,143|151,153|159,176|178,190|192,192|194,206|209,226|228,239|241,247 EEEEE?SSHHHHHHHHHHHHHTT??EE??S??????HHHH???TT?--??EEEEETTEEEEEE?S??TTTHHHHHHHHHHHHHHT??-?EEEEEEEEESSSSS?HHHHHHTT?TT?--??EEETTEEEET--TEEEEEEEE??S---????TTB????-SHHHHHHHHHHHTTHHHH?SHHHHHHHHHHTS?B?HHHHHHHHHHHTT??SSBHHHHHHHHHHHHHHH?HHHHHHHHHHTT?HHHHHHH? 2P62|A PF11537.3_DUF3227_seed 2 102 !Q:0,1|19,19|36,37|44,44|57,57|77,77|80,82|97,100 Q:2,18|20,35|38,43|45,56|58,76|78,79|83,96|101,101 ??HHHHHHHHHHHHHHHHH?TTHHHHHHHHHHHHHS??TTHHHH?HHHHHHHHHHHH?HHHHHHHHHHHHHHHHHHS?TT???SSHHHHHHHHHHHH----T 2P9X|A PF11538.3_Snurportin1_seed 6 43 !Q:0,0|8,10|13,14|16,17|28,28|30,33|35,35 Q:1,7|11,12|15,15|18,27|29,29|34,34|36,42 ?TTTSSTT??-TT??S??HHHHHHHHHT?S??--S?HHHHHHH 3NC0|B PF11539.3_DUF3228_seed 11 216 !Q:0,0|2,2|5,5|16,17|20,23|26,26|42,45|48,48|60,61|63,64|66,73|77,78|85,89|95,95|101,102|109,109|118,119|121,121|142,147|156,156|168,168|171,175|184,185|189,196|214,215 Q:1,1|3,4|6,15|18,19|24,25|27,41|46,47|49,59|62,62|65,65|74,76|79,84|90,94|96,100|103,108|110,117|120,120|122,141|148,155|157,167|169,170|176,183|186,188|197,213 ?S?EE?GGGGGGGSTT-?SS????SS?HHHHHHHHHHHHHHH????EE?SSTTEEEEEEE??S??B------??EEE??TTTGGG?----EEEEE?SSTTS??EEEEEE?TTSHHHHS??B?SEEEEEEEEHHHHHHHHTTS??????EEBTTBSS?SEEEEEEEEES?SS?????HHHHHHTT?-GGG????????HHHHHHHHHHHTTEEEE?? 4FBD|A PF11540.3_Dynein_IC2_seed 10 33 !Q:0,6|9,11|17,22|30,32 Q:7,8|12,16|23,29 ???????EE???EEEEE??????EEEEEEE??? 2PG1|I PF11542.3_Mdv1_seed 2 50 !Q:0,25|41,49 Q:26,40 ??????????????????????????HHHHHHHHHHHHHHT????????? 2PQN|B PF11543.3_UN_NPL4_seed 9 82 !Q:0,6|10,10|17,20|23,24|37,39|42,42|44,48|50,51|59,62|68,70|73,74|76,76|78,81 Q:7,9|11,16|21,22|25,36|40,41|43,43|49,49|52,58|63,67|71,72|75,75|77,77 ???????EEE?SSEEEE????SS??HHHHHHHHHHHT???TT-T?????S??GGGGSSS????TTTTT???TT??E-E???? 2PJH|A PF11544.3_Spc42p_seed 5 77 !Q:0,4|64,76 Q:5,63 --???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?--?????????? 2Q6Q|A PF11545.3_HemeBinding_Shp_seed 3 152 !Q:0,0|16,16|20,23|27,27|43,43|55,55|64,64|80,80|82,83|87,88|110,110|141,142|145,147|151,151 Q:1,15|17,19|24,26|28,42|44,54|56,63|65,79|81,81|84,86|89,109|111,140|143,144|148,150 ?BSEEEEEEEEEEESS?TTT????STT?GGGHHHHHHHHHHHB?SEEEEEEETTS?EEEEEEES?GGGEEEEEEEEEETT?S??EEE??EEEEEEEETTEEEEEEEEEES?SSEEEEEEEEEGGGTEEEEEEEEEEEEESS??SS???SSB? 2Q7A|A PF11546.3_CompInhib_SCIN_seed 4 116 !Q:0,50|69,69|91,91|115,115 Q:51,68|70,90|92,114 ----------------------------???????????????????????HHHHHHSTTHHHHHGGGS?HHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHHH? 3L3O|M PF11547.3_E3_UbLigase_EDD_seed 3 53 !Q:0,3|8,8|22,23|37,37|47,52 Q:4,7|9,21|24,36|38,46 ????GGGS?HHHHHHHHHHSTT??HHHHHHHHHHTTT?HHHHHHHHH?????? 2QHO|B PF11548.3_Receptor_IA-2_seed 6 91 !Q:0,2|10,10|13,14|32,32|51,53|56,58|80,80|88,90 Q:3,9|11,12|15,31|33,50|54,55|59,79|81,87 ???EEEEEES?TT??HHHHHHHHHHHHHHHTS?GGGEEEEEEETTEEEEEE???TT???HHHHHHHHHHTHHHHHHHHTS?EEEEEEE??? 3NG8|A PF11549.3_Sec31_seed 6 51 !Q:0,11|15,15|18,18|24,24|27,29|31,50 Q:12,14|16,17|19,23|25,26|30,30 ??????--????SSS?TT?HHHHS?TT???S???????????????????? 2QTV|D PF11550.3_IglC_seed 2 211 !Q:0,3|7,7|15,16|21,22|30,30|33,35|39,39|47,50|52,55|58,59|63,64|66,67|79,80|84,84|95,95|117,118|122,123|125,125|127,128|131,131|138,138|141,142|145,145|151,151|155,155|162,162|166,168|172,172|184,184|186,187|193,193|198,198|204,204|206,210 Q:4,6|8,14|17,20|23,29|31,32|36,38|40,46|51,51|56,57|60,62|65,65|68,78|81,83|85,94|96,116|119,121|124,124|126,126|129,130|132,137|139,140|143,144|146,150|152,154|156,161|163,165|169,171|173,183|185,185|188,192|194,197|199,203|205,205 ????SSS?HHHHHHT??EEEE??TTTTSSS?SS???EES?EEETTEE????B????TT??GGG??S??BSEEEEEEEEE??SSS?EEEEEEEEEE?HHHHHHHHHHHHHHHHHHGGG??EEE??B?S??EE?TTSSEE?SB??TT?EEEES?TTT?EEEEEE?STT???TTS?EEEEEEEEEEE?S??EEEEE?SSTT?EEEEE?S????? 2QWU|A PF11551.3_Omp28_seed 4 199 !Q:0,38|41,41|43,56|80,80|83,86|98,128|137,137|140,141|144,145|148,149|151,151|157,160|163,166|182,183|194,198 Q:39,40|42,42|57,79|81,82|87,97|129,136|138,139|142,143|146,147|150,150|152,156|161,162|167,181|184,193 ??????????-------?????????-????????????EE?B??????????????EEEEEEEEEEETTEEEEEEEEEE?TT????SEEEEEEEEEE????????------------???????????EEEEEETT?TT-?EE??TT??E-EEEEE????TT????GGGEEEEEEEEETTT??EEEEEEEEEE????? 2R2C|A PF11553.3_DUF3231_seed 51 171 !Q:0,7|12,13|42,44|58,58|75,88|93,93|97,99|125,126|157,162|164,170 Q:8,11|14,41|45,57|59,74|89,92|94,96|100,124|127,156|163,163 ????????GGGS??BHHHHHHHHHHHHHHHHHHHHHHHHHHH???HHHHHHHHHHHHH-HHHHHHHHHHHHHHTT??????????????GGGS?GGG???HHHHHHHHHHHHHHHHHHHHHHHHH??SHHHHHHHHHHHHHHHHHHHHHHHHHHHHT??????B??????? 2RBD|A PF11554.3_DUF3232_seed 3 157 !Q:0,22|37,37|73,73|119,119|125,128|132,135|139,140|152,152|154,156 Q:23,36|38,72|74,118|120,124|129,131|136,138|141,151|153,153 ?????--????????????????HHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?TTTTS????SSS????HHH--HHHHHHHHHHH-T??? 2RDC|A PF11555.3_Inhibitor_Mig-6_seed 6 87 !Q:0,55|59,61|63,63|66,66|69,69|74,86 Q:56,58|62,62|64,65|67,68|70,73 ???????????-????????????----------------------------????GGG???S?EE?TT?TTTS????????????? 4I21|C PF11556.3_EBA-175_VI_seed 11 82 !Q:17,17|34,35|39,39|59,59|75,75|78,78 Q:0,16|18,33|36,38|40,58|60,74|76,77|79,81 HHHHHHHHHHHHHHTTT?SHHHHHHHHHHHHHTS??SSS?HHHHHHHHHHHHHHHHTTS?TTSHHHHHHHHHHHT?TT?TTT 2RJI|A PF11558.3_HET-s_218-289_seed 5 65 !Q:0,7|19,19|25,25|28,28|32,32|34,37|39,41|43,43|55,55|61,61 Q:8,18|20,24|26,27|29,31|33,33|38,38|42,42|44,54|56,60|62,64 ????????EEEEEEEEESS?EEEES?EE?GGG?S????S???S?EEEEEEEEESS?EEEES?EEE 2LBU|A PF11560.3_LAP2alpha_seed 2 235 !Q:0,10|13,32|34,35|52,56|61,64|73,74|76,77|85,97|147,147|150,150|199,201|212,214|220,222|224,234 Q:11,12|33,33|36,51|57,60|65,72|75,75|78,84|98,146|148,149|151,198|202,211|215,219|223,223 ???????????SS????????????????????B??HHHHHHHHHHGGGSSS?????TTTS????HHHHHHHS??B??HHHHHTT?????????????THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS?TT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSS???HHHHHHHHHS???SSBSS???S??????????? 2V0X|A PF11563.3_Protoglobin_seed 104 216 !Q:0,0|13,17|49,50|59,59|63,78|81,81|100,105|109,113|124,124|140,143|145,147|170,183|211,211|214,215 Q:1,12|18,48|51,58|60,62|79,80|82,99|106,108|114,123|125,139|144,144|148,169|184,210|212,213 ?HHHHHHHHHHTT??---HHHHHHHHHHHHHHGGGHHHHHHHHHHHHHT?-HHHHGGGB?TTS----------------SB?HHHHHHHHHHHHHHHHHH------HHS?---?SHHHHHHHHH-HHHHHSTTTTTTTTT????S???HHHHHHTHHHHHHHHHHHHTTT?-----------??HHHHHHHHHHHHHHHHHHHHHHTGGGB?TT?? 3QZX|A PF11564.3_BpuJI_N_seed 2 294 !Q:0,3|7,7|9,16|37,37|57,57|59,59|61,62|79,80|91,91|101,102|114,115|118,118|122,122|134,135|137,137|148,150|157,158|160,160|178,180|196,202|205,206|230,230|233,233|237,237|254,255|258,258|263,263|265,268|270,270|287,293 Q:4,6|8,8|17,36|38,56|58,58|60,60|63,78|81,90|92,100|103,113|116,117|119,121|123,133|136,136|138,147|151,156|159,159|161,177|181,195|203,204|207,229|231,232|234,236|238,253|256,257|259,262|264,264|269,269|271,286 ????TTS-B????????SSSTTHHHHHHHHHHHHHHH?SEEHHHHHHHHHHHHHHHH?T-T??HHHHHHHHHHIIIIIS??EEEETTEEEE?HHHHHHHHH??HHHHHHHHHHH??BS?SSS?HHHHHHHHHTT??B?HHHHHHHHHH---HHHHTT??B?HHHHHHHTTTBHHHHTT???HHHHHHHHHHHHHTT???????TT??HHHHHHHHHHHHHHHHHTTSEEE?SS?EEE?GGGHHHHHHHHTTTTS??SS?GGGS?T----T?HHHHHHHHHHHHHHHH??????? 2VLA|A PF11565.3_PorB_seed 4 114 !Q:0,15|19,19|35,37|40,40|54,54|61,61|69,75|94,113 Q:16,18|20,34|38,39|41,53|55,60|62,68|76,93 ?????????--?????TTS?HHHHHHHHHHHHHTT???TT?BHHHHHHHHHHHH?SHHHHH?HHHHHHH-------HHHHHHHHHHHHHTTSSB??------???????????? 2VQL|A PF11566.3_PI31_Prot_N_seed 42 281 !Q:10,11|29,29|35,37|39,62|67,68|71,99|103,104|110,111|123,128|146,148|153,153|169,169|171,188|193,193|200,207|219,266|270,280 Q:0,9|12,28|30,34|38,38|63,66|69,70|100,102|105,109|112,122|129,145|149,152|154,168|170,170|189,192|194,199|208,218|267,269 HHHHHHHGGG??SHHHHHHHHHHHHHHTT-TEEEE---E------------------------ESSS??TT???--------------------------BSS??TTTTS-?SSEEEEEEEES??--??EEEEEEEEETTEEEEEE---EETT-TTEEEEEEEEHHHHB?T------------------TSTT?HHHHBS?-------HHHHHHHHHHH------------------------------------------------TTS??????????? 2VT8|A PF11567.3_PfUIS3_seed 2 101 !Q:0,4|8,19|42,42|52,52|69,72|99,100 Q:5,7|20,41|43,51|53,68|73,98 ?????TTS????????????HHHHHHHHHHHHHHHHHHHHHS?HHHHHHHTT?HHHHHHHHHHHHHHTT????HHHHHHHHHHHHHHHHHHHHHHHHHH?? 2VWA|A PF11569.3_Homez_seed 9 57 !Q:1,10|21,24|37,38|51,52|55,56 Q:0,0|11,20|25,36|39,50|53,54 S??????????HHHHHHHHHT????TTHHHHHHHHTT??HHHHHHHHHHHS??SS?? 2KT0|A PF11570.3_E2R135_seed 2 141 !Q:0,8|67,67|109,115|136,140 Q:9,66|68,108|116,135 ?????????TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSTT?TTSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-------HHHHHHHHHHHHHHHHHHTT????? 1JCH|A PF11572.3_DUF3234_seed 2 103 !Q:0,5|7,7|17,19|34,34|46,46|49,50|56,56|73,74|80,81|84,84|87,87|100,102 Q:6,6|8,16|20,33|35,45|47,48|51,55|57,72|75,79|82,83|85,86|88,99 ??????S?EEEEESSTT???EEEETTEEEEEEBS?HHHHHHHHHTS?SS??EEEEE?SHHHHHHHHHHHHHTT??EEEES??SS?SS?EEEEHHHHHHHH??? 2Z0R|A PF11574.3_DUF3235_seed 4 100 !Q:0,1|5,6|15,17|36,37|42,48|63,69|82,82|99,99 Q:2,4|7,14|18,35|38,41|49,62|70,81|83,98 -?TTS??HHHHTTTS--?HHHHHHHHHHHHHHHHHT??HHHH-------HHHHHHHHHHHHHH???????HHHHHHHHHTTT?HHHHHHHTHHHHHHHT? 3B4Q|A PF11576.3_DUF3236_seed 7 154 !Q:15,17|19,20|34,34|36,36|40,43|59,62|65,66|68,69|91,92|101,101|107,107|118,118|126,127|132,134|152,153 Q:0,14|18,18|21,33|35,35|37,39|44,58|63,64|67,67|70,90|93,100|102,106|108,117|119,125|128,131|135,151 HHHHHHHHHHHHHTT???S??HHHHHHHHHHHHH?S?EEE????HHHHHHHHHHHHHTT????EE??S??GGGGGSSSHHHHHHHHHHHHH??SEEEEEEE?SSTTS?EEEEEEETTS?EEEEEEE??TTTS???HHHHHHHHHHHHHHTTT?? 3BRC|A PF11577.3_NEMO_seed 9 68 !Q:0,5|65,67 Q:6,64 ??????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??? 3BRV|B PF11578.3_DUF3237_seed 66 320 !Q:0,1|3,4|11,18|21,27|30,32|34,38|43,59|65,72|77,77|82,83|91,96|98,122|126,126|128,128|130,130|137,138|142,169|179,180|184,193|196,202|214,220|226,226|231,233|235,238|240,245|247,247|249,249|252,267|277,277|279,279|283,283|290,290|294,297|301,311 Q:2,2|5,10|19,20|28,29|33,33|39,42|60,64|73,76|78,81|84,90|97,97|123,125|127,127|129,129|131,136|139,141|170,178|181,183|194,195|203,213|221,225|227,230|234,234|239,239|246,246|248,248|250,251|268,276|278,278|280,282|284,289|291,293|298,300|312,319 ??E--EEEEEE--------EE-------EE???E-----EEEE-----------------ETTTE--------EEEE-EEEE--EEEEEST------T??-----------------------EEE?T-T?EEEEEE?-TTS---------------------------?EEEEEEEEE--EET----------TS------?EEEEEEEEEEE??-----GGGHH-HHHH---T????G------G-G?EE----------------EEEEEEEES-S-GGG-GGGGSS?EEE----EEE????-?-----EEEEEEEE 3C5O|A PF11579.3_DUF3238_seed 2 194 !Q:0,2|12,13|17,19|22,22|26,27|33,37|39,39|41,42|47,47|70,71|78,78|82,82|89,92|116,117|120,120|124,125|135,135|139,139|147,147|149,149|161,162|170,170|176,177|185,186|193,193 Q:3,11|14,16|20,21|23,25|28,32|38,38|40,40|43,46|48,69|72,77|79,81|83,88|93,115|118,119|121,123|126,134|136,138|140,146|148,148|150,160|163,169|171,175|178,184|187,192 ???EEEEEEEEE??SSB???EE?TTT??EEEEB?????S?S??TTSS?SSEEEEEEEETTTTEEEEEEEE??EEEEEE?TTS?EEEEEE????TTEEEEEEEEETTEEEEEEEEEE??TT?TTS??EEEEEEEEE?TTS?EEEEEEE?S?SEEEEEEEETT??EEEEEEE?HHHHT??GGGGSSS??EEEEEE? 3C5P|A PF11580.3_DUF3239_seed 7 134 !Q:0,14|24,24|27,27|36,36|39,39|43,45|55,56|59,60|64,64|68,68|77,82|93,93|103,105|117,117 Q:15,23|25,26|28,35|37,38|40,42|46,54|57,58|61,63|65,67|69,76|83,92|94,102|106,116|118,133 ???????????????EEEEEEEEE?SS?EEEEEEEE?BS?TTS???EEEEEEEES??TT??TTS?STT?EEEEEEEE----??EEESSSEEES?EEEEEGGGT???HHHHHHHHHHS?HHHHHHHHHTGGGHHH 3C8I|A PF11581.3_Argos_seed 3 134 !Q:14,14|19,19|21,22|27,28|45,45|48,49|62,63|66,67|78,81|83,84|87,87|109,110|112,113|118,124 Q:0,13|15,18|20,20|23,26|29,44|46,47|50,61|64,65|68,77|82,82|85,86|88,108|111,111|114,117|125,133 SEEEETTEEEEESS?STTS?B??TTTS??EEEEEETTTTEEEEEE?SB??TTEEEEEEEEEE??TT??SEEEEEEEEE????B??TT?EEEEEEEEEEETTEEEEEEEE??B??TTEE??-----SSTTSTTEE 3C9A|A PF11582.3_DUF3240_seed 11 103 !Q:0,1|6,6|26,27|30,33|43,55|87,88|95,95|97,102 Q:2,5|7,25|28,29|34,42|56,86|89,94|96,96 ??SEEE-EEEEEEGGGHHHHHHHHTT?-TT????EEEEEEEEE?????????????EEEEEEEEEEEEEGGGHHHHHHHHHHHTTTS??EEEEEE?S?????? 2Z0G|A PF11583.3_AurF_seed 33 342 !Q:0,30|44,44|49,49|54,60|66,67|71,71|74,74|78,78|83,83|90,90|128,128|134,134|168,178|191,193|197,197|214,214|223,223|226,226|228,228|261,263|283,285|295,298|302,302|312,325|327,328|340,340 Q:31,43|45,48|50,53|61,65|68,70|72,73|75,77|79,82|84,89|91,127|129,133|135,167|179,190|194,196|198,213|215,222|224,225|227,227|229,260|264,282|286,294|299,301|303,311|326,326|329,339|341,341 ????------?????????????????????HHHHHHHHHHHHH?HHHH?TTGG-------GGGTT??TTS?SS?GGG?TTTT?HHHHTS?HHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHT?STTTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT???-???????HHHHHHHHHHTT???HHH-HHHHHHHHHHHHHHSB?HHHHHHHT?SS-S?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS--?HHHHHHHHHHHHHHHHHHH???THHHHHHHH----HHT?TTHHHHHHH?-???????-????B?-HHHHHHHHHTT?T 3CHT|A PF11584.3_Toxin_ToxA_seed 2 118 !Q:0,0|2,20|23,23|30,30|33,33|39,39|50,50|65,65|92,92|102,103|106,106|108,110|116,117 Q:1,1|21,22|24,29|31,32|34,38|40,49|51,64|66,91|93,101|104,105|107,107|111,115 ?B???????????????????EE?HHHHTS?TT?EEEEE?SSSEEEEEEE?SSSEEEEEEEESSS?EEEEEEEEEEETTTEEEEEEEEEEEE?SEEEEEEEE??TT?S???EEEEE?? 1ZLE|A PF11585.3_Stomoxyn_seed 2 42 !Q:0,2|41,41 Q:3,40 ???HHHHHHHHHHHHHHHHHHHTHHHHTTTTGGGTHHHHHH? 1ZRX|A PF11586.3_DUF3242_seed 4 135 !Q:0,0|4,4|13,13|26,26|33,33|41,42|61,61|72,78|83,84|86,86|118,118|134,134 Q:1,3|5,12|14,25|27,32|34,40|43,60|62,71|79,82|85,85|87,117|119,133 ?TTS?HHHHHHTT?BTTBEEEEEEEE-EEETTE-EEEEEEE--EEEETTEEEEEEEEESTT-HHHHHHHHHT???????EEEE--E?SSEEEEEEEETTEEEEEEEETTEEEEEEESS?HHHHHHHHHHHHHTS? 1VR8|A PF11587.3_Prion_bPrPp_seed 8 30 !Q:0,1|26,29 Q:2,25 ??TTTTTTHHHHHHHHHHHHHTTSSS???? 1SKH|A PF11588.3_DUF3243_seed 17 82 !Q:6,6|30,33|45,49|63,64|81,81 Q:0,5|7,29|34,44|50,62|65,80 HHHHHH-HHHHHHHHHHHHHHHHHHHHTTT????HHHHHHHHHHT?????SHHHHHHHHHHHH??HHHHHHHHHHHHHHHT? 3D0W|A PF11589.3_DUF3244_seed 10 120 !Q:0,7|9,14|16,18|22,38|45,46|58,59|72,73|81,81|92,92|96,96|110,110|119,119 Q:8,8|15,15|19,21|39,44|47,57|60,71|74,80|82,91|93,95|97,109|111,118 ????????E------E???EEE?-----???????????SEEEEE--ETTEEEEEESS??SEEEEEEEETTT??EEEEEEE?GGGTTEEEEE?TTS?SEEEEEEEEEESS?EEEEEEEE? 3SD2|A PF11590.3_DNAPolymera_Pol_seed 8 41 !Q:0,0|11,11|19,24|40,40 Q:1,10|12,18|25,39 ?HHHHHHHHTT?EEEETTS-----?HHHHHHHHHHHHHHH? 1B44|D PF11591.3_2Fe-2S_Ferredox_seed 2 34 !Q:0,0|13,13|26,26|28,33 Q:1,12|14,25|27,27 ?THHHHHHHHHHT-TSGGGTTTTSSS?S-????? 1FCT|A PF11592.3_AvrPto_seed 2 105 !Q:0,3|20,21|33,33|58,58|63,64|67,67|70,72|100,104 Q:4,19|22,32|34,57|59,62|65,66|68,69|73,99 ????HHHHHHHHHHHHHHSS??SHHHHHHTTTS?HHHHHHHHHHHHHHHHHHHHHTTS?TTTS??SS?SS???HHHHHHHHHHHHHHHHHHHHHHHHHHH????? 1R5E|A PF11598.3_COMP_seed 12 71 !Q:0,0|7,9|29,51|66,66|70,70 Q:1,6|10,28|52,65|67,69 ?SHHHHH---HHHHHHHHHHHHHHHHHHH-----------------------HHHHHHHHHHHHHT?TTT? 3V2Q|A PF11599.3_AviRa_seed 2 249 !Q:0,3|7,7|9,12|22,23|28,31|49,49|51,51|59,59|85,85|119,120|144,145|151,152|155,155|166,168|175,176|186,188|204,204|207,207|212,212|219,221|225,226|241,242 Q:4,6|8,8|13,21|24,27|32,48|50,50|52,58|60,84|86,118|121,143|146,150|153,154|156,165|169,174|177,185|189,203|205,206|208,211|213,218|222,224|227,240|243,248 ????SSS?S????STTSTTTSS??BTTB????HHHHHHHHHHHHTTSSS?S?EEEEETT?TTSHHHHHHHHHSGGGEEEEEEEES?HHHHHHHHHHHGGGSHHHHHHHHHHHHHHHHHH??HHHHHHHHHHHHHHHHHHHTTSS??EEEEE??SS?HHHHHHHHTT???SEEEEE??TTSSSSTTS???HHHHHHHHHHHHTTS?TT?EEEE-EESSSS???TTS??SEEEEETTEEEEEE--EHHHHH 1O9G|A PF11601.3_Shal-type_seed 4 29 !Q:0,2|16,28 Q:3,15 ???TTTHHHHHHHHTT????????????? 2NZ0|B PF11602.3_NTPase_P4_seed 3 369 !Q:0,18|20,20|22,22|25,25|27,31|37,37|46,47|59,61|80,82|100,102|109,118|123,130|136,136|151,152|156,156|159,165|172,174|180,180|183,185|196,197|214,215|217,217|221,222|230,230|234,234|238,238|258,258|265,269|273,273|302,302|312,368 Q:19,19|21,21|23,24|26,26|32,36|38,45|48,58|62,79|83,99|103,108|119,122|131,135|137,150|153,155|157,158|166,171|175,179|181,182|186,195|198,213|216,216|218,220|223,229|231,233|235,237|239,257|259,264|270,272|274,301|303,311 ???????????????????S?B?SS?H-----HHHTS-BGGGTSSB??TTEEEEEETTE---EEEEEHHHHHHHHHHHHH???HHHHHHHHTTGGGGTEE???BTTTTT----------TSTT????????TTSEE?SSSTTEESEEEEEE??TTS?HH-------HHHHTT-??SEEEE?SS???GGGGSTTEEE??SHHHHHHHHHHHHHTT??E-EEE??HHHHHHS?SSB?GGG?BHHHHHHHHHHHHHHHHTT?EEEEEE?????GGG-HHHHHHHHHTTSSEEEEEETTEEEEEEE-EETTEEEEE?-???????????????????????????????????----???????????????? 1W47|A PF11603.3_Sir1_seed 2 133 !Q:0,4|28,28|31,31|39,40|51,54|61,62|64,66|70,71|79,80|88,88|95,110|121,121|125,125 Q:5,27|29,30|32,38|41,50|55,60|63,63|67,69|72,78|81,87|89,94|111,120|122,124|126,132 ?????EESSSSEEEETTEEEETTTTEEE?TT?THHHHHS-?HHHHHHHHTS????GGGGTT??S?--EEE??HHHHHHS??EEEEEEE?TTSSEE???????????-????EEEEEEEEEE?SSS?EEEEEET 1Z1A|A PF11604.3_CusF_Ec_seed 186 82 !Q:17,18|22,23|27,29|37,42|45,46|49,52|55,55|64,64|69,69|72,73|80,81 Q:0,16|19,21|24,26|30,36|43,44|47,48|53,54|56,63|65,68|70,71|74,79 EEEEEEETTTTEEEEEE??BGG--GTB-?-SEEEEEE-??---TT?-EE????TT?EEEEEEEE-ETTE-EE--EEEEEE?? 2QCP|X PF11605.3_Vps36_ESCRT-II_seed 22 96 !Q:0,0|2,2|6,6|8,10|13,14|30,31|33,33|36,36|55,55|60,60|72,75|79,79|83,83|87,87|96,96 Q:1,1|3,5|7,7|11,12|15,29|32,32|34,35|37,54|56,59|61,71|76,78|80,82|84,86|88,95 ?B?TTS?B???TT??EEEEEEEEEEEETTE--E?TT?SSEEEEEESSEEEEEESS?HHHH?EEEEGGGEEEE----EEE?SSS-SSS?EEEEEESS- 2DX5|A PF11606.3_AlcCBM31_seed 3 94 !Q:0,2|6,6|25,31|45,45|58,59|62,62|87,88|90,93 Q:3,5|7,24|32,44|46,57|60,61|63,86|89,89 ???GGG?SSEEEEEEETTEEEEEEE??-????SSEEEEETTEEEE?EEETTEEEEEEE??TT?EEEEEEEEEETTTTEEEEEEEEEE??S???? 2COV|D PF11607.3_DUF3247_seed 7 102 !Q:0,2|4,4|6,7|9,10|25,25|28,28|38,38|47,49|55,55|58,59|70,70|75,75|77,77|91,101 Q:3,3|5,5|8,8|11,24|26,27|29,37|39,46|50,54|56,57|60,69|71,74|76,76|78,90 ???B?S??B??HHHHHHHHHHHHTS?TT?EEEEEETTS?EEEEEESS???EEEEE?TT??EEEEEEEEEE?SSSS?S?EEEEGGGEEEEEE?????-????? 2E12|A PF11608.3_Limkain-b1_seed 5 94 !Q:9,10|14,17|34,35|39,40|43,43|64,65|70,71|77,78|80,93 Q:0,8|11,13|18,33|36,38|41,42|44,63|66,69|72,76|79,79 SSEEEEEES??TTS?---HHHHHHHHHHHHHTTT??EEE??TT?EEEEESSHHHHHHHHHHHTT??SSSS??EEESS??S?????????---?? 2DIU|A PF11609.3_DUF3248_seed 2 63 !Q:5,6|14,14|19,19|37,39|41,43|55,55|61,62 Q:0,4|7,13|15,18|20,36|40,40|44,54|56,60 HHHTT??EEEEEEE?SSSS?EEEEEEEGGGHHHHHHS???B???HHHHHHHHHTT?EEEEE?? 2E6X|A PF11610.3_Ste5_seed 2 30 !Q:0,1|9,24|26,29 Q:2,8|25,25 ??EEEEEEE????????????????S???? 2F49|C PF11611.3_DUF4352_seed 49 179 !Q:0,1|4,4|8,8|10,10|21,26|30,30|33,33|39,47|49,51|64,65|69,69|76,76|82,83|86,87|89,92|95,95|101,106|109,125|130,130|133,133|147,147|151,153|158,159|165,166|177,178 Q:2,3|5,7|9,9|11,20|27,29|31,32|34,38|48,48|52,63|66,68|70,75|77,81|84,85|88,88|93,94|96,100|107,108|126,129|131,132|134,146|148,150|154,157|160,164|167,176 ??TT?EEE-E-TTEEEEEEEE------EEE?SS?BEESS?????????B???SEEEEEEEEEEE-?SSS?EEEEGG-GEEEE-?TT??B??-?EE?STTTT------TB---------------??EEEE?TT?EEEEEEEEEESTT?GGG--?EEEE-?HHHHB??STTSGGGGGG?? 3CFU|A PF11612.3_T2SJ_seed 87 309 !Q:0,4|28,61|64,69|72,72|74,75|78,78|81,81|91,91|93,106|112,137|143,144|147,158|160,167|171,172|180,181|183,184|188,191|195,197|202,211|220,221|223,233|236,248|250,250|255,257|260,265|267,267|269,269|276,278|291,294|296,296|304,305|308,308 Q:5,27|62,63|70,71|73,73|76,77|79,80|82,90|92,92|107,111|138,142|145,146|159,159|168,170|173,179|182,182|185,187|192,194|198,201|212,219|222,222|234,235|249,249|251,254|258,259|266,266|268,268|270,275|279,290|295,295|297,303|306,307 ?????HHHHHHHHHHHHHHHHHHHHHTB----------------------------------BS----??EE?T--TS?EE?SEEEESGGG?E--------------EEEEE?????????------------?????EEEEE--EE------------E--------TTE--EEEEEEE??S?-GGG?-??EEE---EEEE?---------EEEEEEEE--E----------?TT-------------S?EESS---SS?-----S?S?HHHHHH???SEEEEEEEETTT----E-EEEEEEE??SS? 3NJE|A PF11613.3_UCN2_seed 4 38 !Q:0,0|4,7|36,37 Q:1,3|8,35 ?GGG????HHHHHHHHHHHHHHHHHHHHHTTSSSSS?? 3N95|E PF11614.3_FixG_C_seed 345 211 !Q:0,8|17,17|20,29|31,34|46,46|50,50|53,53|60,62|64,70|72,76|78,78|81,94|97,108|113,113|116,116|118,123|133,135|139,150|152,154|159,159|166,169|171,187|195,195|198,202|209,210 Q:9,16|18,19|30,30|35,45|47,49|51,52|54,59|63,63|71,71|77,77|79,80|95,96|109,112|114,115|117,117|124,132|136,138|151,151|155,158|160,165|170,170|188,194|196,197|203,208 ?????????SEEEEEEE?SS????-?????S----EEEEEEEEEEE?SSS?EE-EEEEEE---S--?----S-----S?EE--------------ES----------??EEEE?TT?E------EEEEEEEEE--?GGG-----------?S---SSEE-EEEEEE----E-----------------EGGGTEE-EE-----EEEEEE?? 2R39|A PF11615.3_DUF3249_seed 2 60 !Q:0,17|25,27|32,40|42,44|59,59 Q:18,24|28,31|41,41|45,58 ??????????????????HHHHHHT???TTTS?????????S???HHHHHHHHHHHHTT? 2PQR|C PF11616.3_EZH2_WD-Binding_seed 6 30 !Q:0,1|24,29 Q:2,23 ??HHHHHHHHHHHHHHHHHHHHHH?????? 2QXV|B PF11618.3_DUF3250_seed 11 117 !Q:5,5|9,11|14,16|22,25|33,34|45,46|55,56|59,61|71,72|77,81|83,84|86,87|95,95|100,101|116,116 Q:0,4|6,8|12,13|17,21|26,32|35,44|47,54|57,58|62,70|73,76|82,82|85,85|88,94|96,99|102,115 EEEEE?STT???EE???EESSS????EEEEEEE??SHHHHHHHHH??EEEEEEEE?-SS?--EEEEEEEEE??SHHH-----H??S-?EEEEEEE?BSSS??TTSEEEEEEEEEEE? 2YRB|A PF11619.3_P53_C_seed 2 71 !Q:0,1|4,6|10,11|24,24|46,46|49,49|69,70 Q:2,3|7,9|12,23|25,45|47,48|50,68 ??SS???EEE??TTTBEEEEEEES?HHHHHHHHHHHHHHHHHHHHH?TT?HHHHHHHHHHHHHHHHHHH?? 2RP4|A PF11620.3_GABP-alpha_seed 5 91 !Q:0,1|26,26|28,30|33,33|42,44|54,57|68,69|72,74|87,90 Q:2,25|27,27|31,32|34,41|45,53|58,67|70,71|75,86 ??EEEEEEEESSSBGGGHHHHSHHHH?S?-?SS?EEEETTEE-??TTSBTTTSS????SEEEEEEEEE??TT???EEEEEEEEETTS???? 2JUO|A PF11621.3_Sbi-IV_seed 2 69 !Q:0,0|26,28|43,43|65,68 Q:1,25|29,42|44,64 ?HHHHHHHHHHHHHHHHHHHHHHHHH???HHHHHHHHHHHHTS?HHHHHHHHHHHHHHHHHHHHH???? 2WY7|Q PF11622.3_DUF3251_seed 7 166 !Q:0,10|12,24|40,40|47,47|51,53|58,58|61,61|73,73|90,93|104,104|106,106|110,111|123,126|130,130|139,139|141,142|146,147|157,163|165,165 Q:11,11|25,39|41,46|48,50|54,57|59,60|62,72|74,89|94,103|105,105|107,109|112,122|127,129|131,138|140,140|143,145|148,156|164,164 ???????????S?????????????HHHHHHHHHHHHHHH?SSSEEE?TTT???EEEE?SS?EEEEEEEEEEE?SSSEEEEEEEEESSSS????EEEEEEEEEE?S?SSS??EEEEEEEEEEE????SSS?EEEEEEEE?S??GGG??EEEEEEEEE------?S? 2JWY|A PF11623.3_DUF3252_seed 16 53 !Q:0,2|5,5|10,11|19,19 Q:3,4|6,9|12,18|20,52 ???TT?EEEE??TTSTTTT?EEEEEEEETTEEEEEEEETTEEEEEEEEGGGEE 3C4S|A PF11624.3_M157_seed 5 275 !Q:6,6|16,16|24,29|32,32|36,39|63,63|66,66|79,80|85,91|102,102|110,128|161,161|168,175|185,187|193,200|204,208|212,212|215,215|225,229|243,245|247,247|251,252|254,259|261,262|265,274 Q:0,5|7,15|17,23|30,31|33,35|40,62|64,65|67,78|81,84|92,101|103,109|129,160|162,167|176,184|188,192|201,203|209,211|213,214|216,224|230,242|246,246|248,250|253,253|260,260|263,264 EEETTS?EEEEEEETT?SEEEEEE??????EE?TTS????TTSHHHHHHHHHHHHHHHHHHHH?TT?SEEEEEEEEEEE--TTEE-------EEEEEEEESS?EEEEEEE???????????????????HHHHHHHTTHHHHHHHHHHHHHHHHHTTSGGG?EEEEEE??---???EEEEEEESS???EEEEE????????EEE-----EEE?SS?EEEEEEETT?????EEEEETTTEEEEE?--S?BSS??E------E??EE-????????? 4G59|C PF11625.3_DUF3253_seed 28 100 !Q:0,1|3,3|19,19|22,23|25,25|34,41|45,47|75,78|80,82|86,88|90,91|96,99 Q:2,2|4,18|20,21|24,24|26,33|42,44|48,74|79,79|83,85|89,89|92,95 ??S?HHHHHHHHHHHHHHS?TT??B?HHHHHHHH-------?TTS--?GGGHHHHHHHHHHHHHTTSEEEEETTE----E?-?TTT?-?S??EEEE???? 2NS0|A PF11626.3_Rap1_C_seed 81 183 !Q:8,8|10,13|19,19|28,28|40,48|52,57|59,59|61,72|74,82|84,87|89,89|92,94|104,140|147,159|165,169|181,182 Q:0,7|9,9|14,18|20,27|29,39|49,51|58,58|60,60|73,73|83,83|88,88|90,91|95,103|141,146|160,164|170,180 HHHHHHHH?B---?HHHHH-HHHHHTTT?GGGHHHHHHHH---------HHH------T?S------------S--------?T----T?TT???HHHHHHHHS?-----------------------------------?HHHHHH-------------HHHHH---?-HHHHHHHHHHH?? 3CZ6|A PF11627.3_HnRNPA1_seed 8 42 !Q:0,11|13,17|19,23|27,41 Q:12,12|18,18|24,26 ????????????B-????S?????TTS?--?--???-????? 2H4M|C PF11628.3_TCR_zetazeta_seed 43 33 !Q:0,1|30,32 Q:2,29 ??THHHHHHHHHHHHHHHHHHHHHHHHSTT??? 2HAC|A PF11629.3_Mst1_SARAH_seed 11 49 !Q:8,8|48,48 Q:0,7|9,47 HHHHHTTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH? 2JO8|A PF11630.3_DUF3254_seed 10 106 !Q:0,3|9,9|21,24|27,27|56,56|61,63|65,65|73,73|94,94|96,96 Q:4,8|10,20|25,26|28,55|57,60|64,64|66,72|74,93|95,95|97,105 ---?HHHHH-HHHHHHHHHHT--??SS?EEETTEEEEEEEEEEEETTEEEEEEEEE?BTTB---S?EEEEEES?HHHHHHHHHHHHHHHHHHHT?S?HHHHHHHHH 2LRF|A PF11631.3_DUF3255_seed 2 124 !Q:0,8|10,10|12,14|17,17|22,27|32,32|40,40|58,60|68,69|83,83|85,85|92,92|96,96|111,114|118,123 Q:9,9|11,11|15,16|18,21|28,31|33,39|41,57|61,67|70,82|84,84|86,91|93,95|97,110|115,117 ?????????S-S???TT?EEEE??????STTS?SEEEEEE?SSEEEEEEEETTTEEEE???EEEEEEE??SSSEEEEEEESTT?S?EEEEEE?STT?EEEEETTEEEEEEE????SSS?????? 2JOZ|A PF11632.3_LcnG-beta_seed 2 35 !Q:0,3|22,22|27,27|34,34 Q:4,21|23,26|28,33 ????HHHHHHHHHHHHHHHTTT?TTTS?STTGGG? 2JPK|A PF11633.3_SUD-M_seed 6 144 !Q:5,15|21,23|35,36|44,44|58,61|68,68|76,76|80,80|92,94|98,99|108,108|119,120|122,122|127,127|143,143 Q:0,4|16,20|24,34|37,43|45,57|62,67|69,75|77,79|81,91|95,97|100,107|109,118|121,121|123,126|128,142 SEEEE???????????GGGEE???HHHHHHHHHHH??EEEEETT?HHHHHHHHHHTTT????SEEEES-SSEEEEE?SSS?HHHHHHHHHHH???EEE??TTBTTTSB?HHHHHHHHTT??S?EEEE?SSHHHHHHHHHHHHS? 2RNK|A PF11634.3_IPI_T4_seed 2 76 !Q:0,1|10,10|14,14|20,20|24,25|30,30|37,37|42,42|52,54|58,59|75,75 Q:2,9|11,13|15,19|21,23|26,29|31,36|38,41|43,51|55,57|60,74 ??HHHHHHHH?SSS?SSEEE?TTT??EEET?SSTTTT?EEEE?SSEEEEESS???SSS??EEEEHHHHHHHHHHH? 2JUB|A PF11636.3_Troponin-I_N_seed 5 43 !Q:0,1|10,31|42,42 Q:2,9|32,41 ??STTHHHHS??????-----??------???TTHHHHHHHH? 2JPW|A PF11637.3_UvsW_seed 7 56 !Q:3,4|24,27|50,52 Q:0,2|5,23|28,49|53,55 HHT??SHHHHHHHHHHHHHHTTTS--??TTHHHHHHHHHHHHHHHHHHHT???TTT 2JPN|A PF11638.3_DnaA_N_seed 116 92 !Q:0,1|5,5|15,15|17,18|20,21|34,35|39,53|71,80 Q:2,4|6,14|16,16|19,19|22,33|36,38|54,70|81,91 ??HHH-HHHHHHHHH?S??H--HHHTTTTSEEEE?-SSE---------------EEEEESSHHHHHHHHHT----------HHHHHHHHHHH 2E0G|A PF11639.3_HapK_seed 4 104 !Q:0,0|11,11|33,33|44,47|50,50|52,52|62,62|96,97|100,103 Q:1,10|12,32|34,43|48,49|51,51|53,61|63,95|98,99 ?EEEEEEEEES?GGGHHHHHHHHHHTHHHHGGG?TTEEEEEEEE????TT?S?SEEEEEEES?HHHHHHHHTSHHHHHHHHHHHHHEEEEEEEEEE??TT???? 2JDJ|A PF11641.3_Antigen_Bd37_seed 4 239 !Q:0,2|5,8|28,29|31,33|51,53|73,74|76,77|91,91|97,108|134,134|137,137|142,144|163,164|166,166|176,177|181,182|186,186|198,200|206,208|210,211|233,234|237,238 Q:3,4|9,27|30,30|34,50|54,72|75,75|78,90|92,96|109,133|135,136|138,141|145,162|165,165|167,175|178,180|183,185|187,197|201,205|209,209|212,232|235,236 ???HH----HHHHHHHHHHHHHHHHHHH??S???TTHHHHHHHHHHHHTTT???HHHHHHHHHHHHHHHHHHH??S??HHHHHHHHHHHHH-HHHHT??????????-?HHHHHHHHHHHHHHHHHHHHHHTSS?HH-HHHH---HHHHHHHHHHHHHHHSSS??S?HHHHHHHHH??STT??TTT?HHHHHHHHHHH---HHTSS???H--HHHHHHHHHHHHHHHHHHHHH??SS?? 2LUD|A PF11642.3_Blo-t-5_seed 7 119 !Q:0,9|11,14|17,18|48,49|82,84|116,118 Q:10,10|15,16|19,47|50,81|85,115 ??????????S????SS??HHHHHHHHHHHHHHHHHHHHHHHHHHHHH??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS??? 2JMH|A PF11644.3_DUF3256_seed 9 206 !Q:0,9|18,19|23,23|27,27|39,39|41,42|45,45|52,52|62,62|76,76|89,89|99,99|103,103|114,115|118,118|123,128|134,134|137,138|142,142|153,153|155,156|162,162|173,173|179,179|191,194|200,200 Q:10,17|20,22|24,26|28,38|40,40|43,44|46,51|53,61|63,75|77,88|90,98|100,102|104,113|116,117|119,122|129,133|135,136|139,141|143,152|154,154|157,161|163,172|174,178|180,190|195,199|201,205 ??????????HHHHHHHH??TTT?TTS?HHHHHHHHHHH?S??SS?EEEEEE?TTSSEEEEE-EETTEEEEEESSS?EEEEEEEESSSS?EEEEEEEEE?SSS?EEEEEEEETT??EE?GGGT?-????GGGGB?TT??TTS-HHHHHHGGGG?S??EEEEE?SSSSEEEEEE?SGGGS?TTTHHHHTTTB????EEEEE?SSSEE 2P3P|A PF11645.3_PDDEXK_5_seed 2 149 !Q:0,0|21,21|33,33|51,51|64,64|69,69|74,74|78,80|84,84|115,116|120,120|123,124|132,132|144,148 Q:1,20|22,32|34,50|52,63|65,68|70,73|75,77|81,83|85,114|117,119|121,122|125,131|133,143 ?THHHHHHHHHHHHHHHHHTT?EEEEESSTTSS?SEEEEETTEEEEEEEEE?EEETTTTEEEEE?SEEE?SSSS?EEE???TTS?SEEEEEETTTTEEEEEEHHHHHTSSSEEEE??SSS?SS??TTGGGBT?THHHHHHHHTT????? 2OST|A PF11646.3_DUF3258_seed 4 111 !Q:12,12|40,40|44,44|66,66|70,70|80,82|86,96|99,99 Q:0,11|13,39|41,43|45,65|67,69|71,79|83,85|97,98|100,110 EETTTTEEEEEE?SEEEEEEEEEEEGGGTEEEEEEEEEEE?TTS?EEEEEEEEEEEEHHHHHHHTT?SSS?HHHHHHHHT???TTS???????????SS?HHHHHHHHHHH 3II3|A PF11647.3_PMT_C_seed 14 72 !Q:0,0|8,9|34,41|63,64|66,66 Q:1,7|10,33|42,62|65,65|67,71 ?HHHHHHH--HHHHHHHHHHHHHHHHHHHHHHHH??------HHHHHHHHHHHHHHHHHHHHH??S?HHHHH 2EBH|X PF11648.3_RIG-I_C-RD_seed 14 132 !Q:2,2|10,11|30,31|36,36|46,48|51,52|66,67|69,70|83,83|88,88|94,97|101,101|107,108|110,110|114,114|117,119|121,123 Q:0,1|3,9|12,29|32,35|37,45|49,50|53,65|68,68|71,82|84,87|89,93|98,100|102,106|109,109|111,113|115,116|120,120|124,131 GG?EEEETTT??EEEEGGGEEEETTTEEEE??GGGG-GGEEEEEEE???SS??SSEEEEEEEEETT--T??EEEEEEEETTEE-EEEE?GGGEE----EEE-TTEEE??S?GGG?SS???B?-?HHHHHHHH 2YKG|A PF11650.3_P22_Tail-4_seed 6 185 !Q:0,7|9,10|25,26|28,29|49,51|56,64|68,72|77,80|101,104|119,122|131,141|144,147|151,151|153,153|158,159|161,184 Q:8,8|11,24|27,27|30,48|52,55|65,67|73,76|81,100|105,118|123,130|142,143|148,150|152,152|154,157|160,160 ?-??????S??BHHHHHHHHHHHHS??S??SSTTTTTHHHHHHHHHHSS--?TTSS?????????SSS?--??SSSB????GGGHHHHHHHHHHHHGGGGT????HHHHHHHHHHHHHH----HHHHHHHT??----?????SS????SSS?S?SSSS??S????????????????------?? 3LJ4|Y PF11680.3_DUF3276_seed 27 149 !Q:0,15|25,26|39,39|43,43|54,54|58,65|94,102|106,148 Q:16,24|27,38|40,42|44,53|55,57|66,93|103,105 ?----????----???TTEEEEEEE??SSSEEEEEEEEE?TTS?EEEEEEEEEE?TTS?-------EEEEEEEEEGGGHHHHHHHHHHHHHHHH---------HHS???-???????????????????--------???????????? 3N8B|A PF11698.3_V-ATPase_H_C_seed 34 151 !Q:2,3|16,21|26,34|46,46|62,64|72,78|100,101|109,111|126,128|149,150 Q:0,1|4,15|22,25|35,45|47,61|65,71|79,99|102,108|112,125|129,148 HT??HHHHHHHHHHHT????-?GGGG?--------HHHHHHHSGGG-SSGGGHHHHHHHHHH---HHHHHTT----???SHHHHHHHHHHHHHHHHHHHH-?TTHHHHH---HHHSHHHHHHHHTS?--SSHHHHHHHHHHHHHHHHHS?? 1HO8|A PF11699.3_CENP-C_C_seed 11 89 !Q:0,3|6,7|11,11|13,13|21,21|27,27|32,33|61,61|66,66|69,69|76,76|78,78|81,81 Q:4,5|8,10|12,12|14,20|22,26|28,31|34,60|62,65|67,68|70,75|77,77|79,80|82,88 ????EE??TTT?S?EEEEEEE?SSGGG?EEEE??SEEEEEEEEESEEEEEETTEEEEEETT?EEEE?TT?EEEEEE?S-SS?EEEEEEE 2VPV|A PF11701.3_UNC45-central_seed 31 327 !Q:17,17|21,21|38,38|43,69|89,90|94,95|98,102|120,122|143,147|150,151|154,187|215,219|231,242|245,245|282,282|284,284|286,286|289,314 Q:0,16|18,20|22,37|39,42|70,88|91,93|96,97|103,119|123,142|148,149|152,153|188,214|220,230|243,244|246,281|283,283|285,285|287,288|315,326 THHHHHHHHHHHHHHHT?TTS?HHHHHHHHHHHHHHTT?TTTT---------------------------HHHHHHHTTHHHHHHHHHT??SSS??SS?????TTHHHHHHHHHHHHHHT??-SHHHHHHHHHHHHHHHHHHH-----SS??HH----------------------------------HHHHHHHHHHHHHSSSHHHHHHHHHTT-----THHHHHHHHHH------------SS?HHHHHHHHHHHHHHTTSHHHHHTTHHHHHHHHHHHT-T?S?HH--------------------------HHHHHHHHHHHH 4I2W|A PF11706.3_zf-CGNR_seed 80 54 !Q:4,8|12,14|18,19|23,27|30,37|52,53 Q:0,3|9,11|15,17|20,22|28,29|38,51 GEEE?---?STT???EEE??SSS?????SS--------HHHHHHHHHHTTTT?? 3H0N|A PF11713.3_Peptidase_C80_seed 23 245 !Q:0,0|2,2|10,28|30,31|40,43|59,59|62,67|69,69|76,91|95,101|110,111|114,118|122,123|142,142|150,161|163,164|172,173|175,175|177,182|200,200|202,212|220,220|224,236|240,240|245,245 Q:1,1|3,9|29,29|32,39|44,58|60,61|68,68|70,75|92,94|102,109|112,113|119,121|124,141|143,149|162,162|165,171|174,174|176,176|183,199|201,201|213,219|221,223|237,239|241,244 ?S?SEEEEEE?------------------S??HHHHHHHH----HHHHHTGGGEEEEEE?TT------S?EEEEES?---------------GGG?-----?SSEEEEEE??EE?--??TTS??EETTEEHHHHHHHHHHHH-HHHHHHH????------??S--EEEEESS??S?T------TSSSSHHHHHHHHHHHT-T?--------??EEEEESS?EEE------------?TTS?EEEE- 3FZY|A PF11715.3_Nup160_seed 25 723 !Q:1,19|22,40|50,52|54,54|60,60|64,64|70,75|85,90|96,104|110,110|113,113|115,118|122,122|124,124|131,135|144,144|148,148|161,182|184,187|189,190|192,192|195,195|200,200|207,215|228,228|237,242|251,262|269,277|279,281|283,285|288,288|303,305|311,311|324,372|378,385|391,393|396,398|409,412|416,422|425,426|428,428|433,434|437,456|459,462|471,471|474,474|477,477|485,485|499,500|503,503|506,507|509,531|536,543|550,552|557,558|562,562|573,577|581,586|598,599|611,612|628,631|633,633|638,647|649,649|676,677|681,684|687,690|692,700|707,708|712,713|715,717 Q:0,0|20,21|41,49|53,53|55,59|61,63|65,69|76,84|91,95|105,109|111,112|114,114|119,121|123,123|125,130|136,143|145,147|149,160|183,183|188,188|191,191|193,194|196,199|201,206|216,227|229,236|243,250|263,268|278,278|282,282|286,287|289,302|306,310|312,323|373,377|386,390|394,395|399,408|413,415|423,424|427,427|429,432|435,436|457,458|463,470|472,473|475,476|478,484|486,498|501,502|504,505|508,508|532,535|544,549|553,556|559,561|563,572|578,580|587,597|600,610|613,627|632,632|634,637|648,648|650,675|678,680|685,686|691,691|701,706|709,711|714,714|718,722 E????---------------SS???????????????????HHHHHHTTS?-?S?EEEEE?SSS?EEEEE------EETTEEEEE??????SSSSS??------?EEEEE?SS?S?---SSS?S?EEEESS-----SEEEEEEE?SSS?EEEEEEEHHHHH?---------------??????S--??B??B?SS?TTTS?EEEEEE?--------SSSEEEEEETTS?EEEEEEET------TEEEEEEE????????????TTTTTS---------S???S???TT?EEEEEEETTTTEEE---EEETT?EEEEEETTTTEE-------------------------------------------------EEEEE-----???SSSTT???SS???EEESSSSEEE????GGG???????EE??B?SSSB??EE??????--------??????TT????EEEEEEEE?TT?TT?EEEEEEE-EETTEEEEEEEEE??SS?SS??E-----------------------EEEE????????TTTTTS???SGGG-?SSH-HHHHHHHHHH??-??HHH------HHHHHHHTTSS??STTHHHHHHHH??HHHHHHHHHHHHHTT????B?SSSS?---------B?HHHHHHHHHHHHHHHHHHHHHTSSSS??EEE????TT----T??------?EEEETT??EEE--E???HHHHH 3H7N|A PF11716.3_MDMPI_N_seed 100 199 !Q:15,16|20,21|26,26|28,28|32,32|41,43|55,83|85,88|91,93|97,102|104,104|106,107|112,124|135,135|157,158|164,164|167,167|169,169|173,173|180,181|198,198 Q:0,14|17,19|22,25|27,27|29,31|33,40|44,54|84,84|89,90|94,96|103,103|105,105|108,111|125,134|136,156|159,163|165,166|168,168|170,172|174,179|182,197 HHHHHHHHHHHHHHS?-GGG--TTSB?S-STT?BHHHHHHH---HHHHHHHHHHH-----------------------------H----HH---HHH?????-S?S-?HHHH-------------HHHHHHHTTS?HHHHHHHHHHHHHHHHHHHHT??TGGGG?EE-E?TTS?EEETTH--HHHHHHHHHHHHHHHT? 2NSF|A PF11717.3_Tudor-knot_seed 56 98 !Q:0,1|5,8|15,27|44,46|52,72|79,79|83,83|86,87|91,91|96,97 Q:2,4|9,14|28,43|47,51|73,78|80,82|84,85|88,90|92,95 ??TTS----EEEEEE-------------TTTEEEEEEEEEEEEE---TTTTE---------------------EEEEEE?TTT?SS??EEE?TTTS?? 2RNZ|A PF11720.3_Inhibitor_I78_seed 8 65 !Q:0,1|13,14|21,27|34,34|37,37|41,44|47,47|53,53|64,64 Q:2,12|15,20|28,33|35,36|38,40|45,46|48,52|54,63 --HHHHHHTTTSB??HHHHHH?----??SSEEEE?TT?EEE????TT?EEEEE?TTSBEEEEEE? 1TM7|I PF11721.3_Malectin_seed 62 249 !Q:12,15|24,24|27,27|32,39|42,74|76,78|82,82|87,91|96,108|110,113|119,124|126,131|133,133|136,137|146,147|149,159|164,164|172,172|180,180|184,185|192,195|203,203|206,206|213,218|226,227|236,236|240,240|244,244 Q:0,11|16,23|25,26|28,31|40,41|75,75|79,81|83,86|92,95|109,109|114,118|125,125|132,132|134,135|138,145|148,148|160,163|165,171|173,179|181,183|186,191|196,202|204,205|207,212|219,225|228,235|237,239|241,243|245,248 EEEEEEETSSSE----EETTTEEE?SS?SSTT????????TT---------------------------------S-??SSS?HHHH-----HTTT????-------??S-?--EEEEE------E----??S?EE--EEEEEEEE??S???--------SSSS?EEEEETT-EEEEEEE?HHH--HHSSSS---?EEEEEEE-EE-ETTEEE------ETTEEEE??SEEEEEEE?SSS?SSS-EEEE 2JWP|A PF11723.3_Aromatic_hydrox_seed 7 284 !Q:6,11|17,17|20,31|34,34|41,41|44,45|50,50|60,60|70,70|81,81|85,86|88,89|91,91|100,102|105,107|112,112|114,119|123,123|127,127|139,139|142,144|147,164|180,180|185,185|209,209|223,223|254,254|259,262|279,279|281,281|283,283 Q:0,5|12,16|18,19|32,33|35,40|42,43|46,49|51,59|61,69|71,80|82,84|87,87|90,90|92,99|103,104|108,111|113,113|120,122|124,126|128,138|140,141|145,146|165,179|181,184|186,208|210,222|224,253|255,258|263,278|280,280|282,282 EESSSS---???GGGGS?TT------------TT?TTEEEE-EE??EESS?HHHHHHHHH?TTGGGGGTT?HHHHHTTBEE?SEE--E??S?SGGGEEEE???TT???EEEE?H------HHH?EEE?EEEETTEEEEE?EE?--SB???---------------SEEEEETTTEEEEES?SSTT?EEEEEEEEEETTEEEEEEEEEEE?SSHHHHHHHHHHH-HHTHHHHTTTTTTHHHHHHHHHHHHHHHTS?HHHH????GGGHHHHHHHHHHHHH?S?B? 2DE7|A PF11724.3_YvbH_ext_seed 7 62 !Q:14,14|16,18|20,20|22,23|48,48|50,51|60,61 Q:0,13|15,15|19,19|21,21|24,47|49,49|52,59 HHHHHHHHHHHHHH?S???T-T??HHHHHHHHHHHHHHHHHHHHHHHS?S??HHHHHHHH?? 3B77|A PF11728.3_DUF939_C_seed 30 170 !Q:0,0|28,28|32,34|62,63|94,94|96,98|114,117|139,141|166,167 Q:1,27|29,31|35,61|64,93|95,95|99,113|118,138|142,165|168,169 ?HHHHHHHHHHHHHHHHHHHHHHHHHHH?TTS??-SHHHHHHHHHHHHHHHHHHHHHTGGGS?-HHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?S???HHHHHHHHHHHHHHH????TTHHHHHHHHHHHHHHHHHTS???SSHHHHHHHHHHHHHHHHHHHHHH--HH 3KMI|A PF11734.3_TilS_C_seed 140 113 !Q:2,2|6,12|16,16|18,19|22,26|29,29|41,42|50,50|55,58|61,61|64,64|69,69|77,81|84,95|99,100|102,105|109,111 Q:0,1|3,5|13,15|17,17|20,21|27,28|30,40|43,49|51,54|59,60|62,63|65,68|70,76|82,83|96,98|101,101|106,108|112,112 EE-EES?----??SEE?B--TT----?SS?EEHHHHHHHHT??GGGTTSS?EEEE----TT-EE-EEET-TTEEBGG-----GB?-----------SSS??E----EEE---E 3A2K|A PF11736.3_DUF3299_seed 61 235 !Q:0,1|7,10|13,13|15,26|29,30|33,35|41,59|63,63|68,106|108,108|111,114|134,134|155,158|162,162|171,171|177,185|189,189|198,200|203,204|207,215|229,234 Q:2,6|11,12|14,14|27,28|31,32|36,40|60,62|64,67|107,107|109,110|115,133|135,154|159,161|163,170|172,176|186,188|190,197|201,202|205,206|216,228 ??GGGGS-?--TT-S?-????------SS??HH---HHHHH-------------------HHS?SSTT--------------------------------------?S?TT????GGGTTEEEEEEEEEEEEEE?TTSEEEEEEEESSTTBTTTB????GGG?EEEEEEEE-EESTT---------TTS?EEEEEEEE???EE?-SS?--------EESEEEEEEEEEE?----? 4HSP|A PF11738.3_DUF3298_seed 347 247 !Q:3,11|13,13|15,15|17,18|20,37|42,47|56,62|64,84|89,89|91,124|138,173|175,175|178,179|181,181|184,189|191,191|194,196|200,200|202,204|208,211|213,221|225,233|235,238|247,247 Q:0,2|12,12|14,14|16,16|19,19|38,41|48,55|63,63|85,88|90,90|125,137|174,174|176,177|180,180|182,183|190,190|192,193|197,199|201,201|205,207|212,212|222,224|234,234|239,246 HHH---------H-B?S--S-----------------?HHHH------HHHHHHHH-------H---------------------HHTT?S?---------------------------------HHHHHHTTTTSSS????-------------------------------?S?EE--E?SS------E-EE---EEE?T---TSS----S--------?GGG------?-?E----EEEEEGGG- 3S5T|A PF11741.3_AMIN_seed 172 132 !Q:4,7|10,10|12,12|20,20|22,23|31,36|49,52|59,60|63,65|67,68|71,71|74,76|82,82|87,88|100,100|103,106|110,110|116,116|119,120|124,124 Q:0,3|8,9|11,11|13,19|21,21|24,30|37,48|53,58|61,62|66,66|69,70|72,73|77,81|83,86|89,99|101,102|107,109|111,115|117,118|121,123|125,131 EEEE??--SS?E-EEEEEES-S??EEEEEEE------TTTTEEEEEEES????HHHHGG--GG---G??TT?SS---EEEEE-EEEE--ETTEEEEEEEE-SS---?EEE-EEEEE?SB--TTB?EEEEEEE 4BIN|A PF11760.3_CbiG_N_seed 150 92 !Q:2,3|10,12|14,15|23,23|35,40|44,46|52,52|55,56|63,63|68,68|82,82|85,91 Q:0,1|4,9|13,13|16,22|24,34|41,43|47,51|53,54|57,62|64,67|69,81|83,84 GG??HHHHTT---T-?SEEEEES?HHHHHHHHHHH??---?TTT-??EEEEE?TT??EEEEEE?TTTT-HHHHHHHHHHHTT?EE??????? 3EEQ|A PF11762.3_Arabinose_Iso_C_seed 38 115 !Q:1,1|5,9|13,18|21,22|25,25|37,37|51,53|56,57|60,61|63,63|72,72|84,86|95,96|109,109 Q:0,0|2,4|10,12|19,20|23,24|26,36|38,50|54,55|58,59|62,62|64,71|73,83|87,94|97,108|110,114 S?EEE?????TTT??????EE??BB?SEEEEEEEEEE?SSSEEEEEEEEEE???SS??TT??S?BEEEEESS?HHHHHHHHHHT???SEEEEESS??HHHHHHHHHHHT?EEEEE 2HXG|A PF11766.3_Candida_ALS_N_seed 24 271 !Q:4,4|9,10|13,13|29,31|39,42|54,55|59,59|69,71|74,77|91,94|107,108|130,140|142,142|146,146|165,168|171,171|177,179|185,185|188,188|205,205|209,209|212,213|215,218|224,224|228,229|235,237|239,239|251,252|265,266 Q:0,3|5,8|11,12|14,28|32,38|43,53|56,58|60,68|72,73|78,90|95,106|109,129|141,141|143,145|147,164|169,170|172,176|180,184|186,187|189,204|206,208|210,211|214,214|219,223|225,227|230,234|238,238|240,250|253,264|267,270 EEEE-ETTT??TT?EEEEEEETEEEESSS--?SEEEEEE----TTEEEEEEEEE??TTT?SEEEEEEEE???SS?--?SEEEEEEEEEEEE????SSSHHHHHHTTS??SEEEEEEEEETTEEEEEEEEE????-------S?TTS?EEEEEEEGGGTEEEEEEE????TT?EEEEE---EEEEE?TT-EEEEEEEEEEEEEESB?TTS?BS??B?-??EEEEE?SSE--EEEEE??-B?TTEEEEEEEEE--EESSTTEEEEEE??EEEE 2Y7L|A PF11774.3_Lsr2_seed 69 143 !Q:0,10|12,12|20,24|41,41|62,142 Q:11,11|13,19|25,40|42,61 ????????--?B?TTTSSSB??---EEEEEEETTEEEEEEE?HHHHHHHHHHHHHHHHHSEE??---??-------------------------------------------------------------------------- 4E1P|A PF11776.3_DUF3315_seed 112 55 !Q:1,1|3,5|12,12|17,19|24,28|36,36|38,38|49,49 Q:0,0|2,2|6,11|13,16|20,23|29,35|37,37|39,48|50,54 T?B??-GGGTSG-GGEE???TTSS?????TTEEEEE?S-SEEEEEETTT?BEEEE 2L1S|A PF11778.3_SID_seed 9 140 !Q:6,7|11,13|21,21|24,25|29,30|42,43|60,61|95,100|116,117|121,123|133,139 Q:0,5|8,10|14,20|22,23|26,28|31,41|44,59|62,94|101,115|118,120|124,132 HHHHHH??GGG???HHHHHHH?TT??HHH--HHHHTGGGGGG??HHHHHHHHHHHHHHHT??GGGHHHHHHHHHHHHHTHHHHHHHHHHHHHHHH??????HHHHHHHHHHHHHHH??STT???HHHHHHHHH??????? 3OA7|A PF11783.3_Cytochrome_cB_seed 41 336 !Q:10,29|31,33|35,42|46,46|57,60|65,65|68,69|75,75|77,78|82,83|86,90|92,104|107,110|117,119|122,122|125,126|148,152|154,155|157,168|170,173|175,175|180,186|197,241|243,243|251,259|261,261|263,299|310,311|313,316|321,325|333,334 Q:0,9|30,30|34,34|43,45|47,56|61,64|66,67|70,74|76,76|79,81|84,85|91,91|105,106|111,116|120,121|123,124|127,147|153,153|156,156|169,169|174,174|176,179|187,196|242,242|244,250|260,260|262,262|300,309|312,312|317,320|326,332|335,335 EEEEEGGGTT?------------------?S???B--?-----TTS?BSEETTTEEE----EEES-SB??EEEEE?S-?EEE??TT????-T-------------TS?---EESEEE???TT?TT-?EEEEEEEEEEEEEEETTTTEE?????S--S------------T----T?HHHH-----??HHHHHHHHHH---------------------------------------------H?HHHHHTT???-----?S?E-------------------------------------EEEEEEEEEE??S????GGGS-?--?HHHHSTT??S 1SP3|A PF11789.3_zf-Nse_seed 22 90 !Q:1,5|7,8|11,12|15,15|22,22|30,38|41,43|55,75|78,78|80,80|83,83|88,88 Q:0,0|6,6|9,10|13,14|16,21|23,29|39,40|44,54|76,77|79,79|81,82|84,87|89,89 S?????S--SB??SB?TTTSSB?SSEEEES---------SS-??EEEHHHHHHHS---------------------TT?S?EE?SGGG?S 1JM7|A PF11791.3_Aconitase_B_N_seed 94 213 !Q:9,9|13,13|15,22|36,37|40,41|44,77|88,89|92,92|111,111|116,116|128,128|141,144|146,146|149,165|177,178|184,184|196,196 Q:0,8|10,12|14,14|23,35|38,39|42,43|78,87|90,91|93,110|112,115|117,127|129,140|145,145|147,148|166,176|179,183|185,195|197,212 HHHHHHHHH-HHT-T???????-HHHHHHHHHHHHS??TT-?HH----------------------------------HHHHHHHHSS??TT?HHHHHHHHHHHHHHTTSS?BTTB?HHHHHHHHTTS?SSTTHHHHHHGG----G?TT-----------------THHHHHHHHHT??TTTTH-HHHHHHHHHTT?HHHHHHHHHHHTTHHH 1L5J|A PF11792.3_Baculo_LEF5_C_seed 24 47 !Q:2,3|7,9|12,12|14,14|20,22|26,27|32,32|44,45 Q:0,1|4,6|10,11|13,13|15,19|23,25|28,31|33,43|46,46 SS?-EEE???TT-T?SEEEE---EEE??SSSS?SSEEEEEESSS??E 1QYP|A PF11793.3_FANCL_C_seed 10 78 !Q:0,2|4,4|8,9|12,20|23,27|29,30|32,32|35,38|40,40|56,56|60,61|65,65|69,69 Q:3,3|5,7|10,11|21,22|28,28|31,31|33,34|39,39|41,55|57,59|62,64|66,68|70,77 ???S?SSS??SS?--------TT?????B??S?TT????B?SGGGHHHHHHHHSSS?TTT??EEE?TTT?SEEEGGGG 3K1L|A PF11794.3_HpaB_N_seed 80 342 !Q:0,0|10,10|12,16|24,26|32,32|50,52|54,65|71,76|82,82|88,88|95,98|120,125|144,144|149,163|180,181|186,190|192,192|195,197|199,199|201,204|207,207|214,214|220,220|223,232|241,241|243,243|246,246|249,249|255,256|259,268|272,274|278,278|287,287|295,297|308,309|312,312|318,324 Q:1,9|11,11|17,23|27,31|33,49|53,53|66,70|77,81|83,87|89,94|99,119|126,143|145,148|164,179|182,185|191,191|193,194|198,198|200,200|205,206|208,213|215,219|221,222|233,240|242,242|244,245|247,248|250,254|257,258|269,271|275,277|279,286|288,294|298,307|310,311|313,317|325,341 ?HHHHHHHHT-T??-??EEETTEE?--SSGGG?TTTHHHHHHHHHHHHHH---H-----------?TTTHH------HHEEE?TTTSS-EEEGGG????SHHHHHHHHHHHHHHHHHHSS-??--?THHHHHHHHHHHHHHHHH-HHHH??------------?HHHHHHHHHHHHHHHT??EEEE?????S?TT---S?G----GG?SSTTSS?EEEEE?SS----------EEEEEEEE?S?TT?TT?SEEEE??SS?------?-?GGG---GGG?EEEEEETT?TTEEEEE???TTGGGGGSTT??GG-GSSSS??--???EEEEEEEEEEEGGGEEE 2YYM|A PF11798.3_IMS_HHH_seed 92 38 !Q:4,4|9,10|13,14|22,23|30,30|34,34|37,37 Q:0,3|5,8|11,12|15,21|24,29|31,33|35,36 GGGH-HHHH--HH?-BSTTSTT??HHHHHH-HTT-TT? 3BQ0|A PF11799.3_IMS_C_seed 106 242 !Q:0,29|35,35|37,37|39,47|54,59|62,62|76,79|85,99|107,120|125,133|137,137|140,140|145,147|155,158|165,165|168,170|174,177|182,184|190,196|200,202|205,206|208,213|217,217|227,236|238,241 Q:30,34|36,36|38,38|48,53|60,61|63,75|80,84|100,106|121,124|134,136|138,139|141,144|148,154|159,164|166,167|171,173|178,181|185,189|197,199|203,204|207,207|214,216|218,226|237,237 ?????------------------???????EEEEE?S-S?--??---?SHHHHH------HH-HHHHHHHHHHHHH----HTTEE---------------EEEEEEE--------------EEEE--------?TTS?SB?SSTT???SEEEEEE----EEEEEE-EE??-HHH----HHHH---HHHHH-------HTS???GG--G------EEE-EEEEEEEEE----------E???? 4EEY|A PF11806.3_DUF3327_seed 35 263 !Q:0,0|2,19|24,35|39,39|42,42|47,64|80,88|90,90|93,93|97,105|109,143|150,150|153,153|157,172|180,182|185,188|191,199|214,220|222,223|226,226|228,228|232,232|235,243|252,252|255,258 Q:1,1|20,23|36,38|40,41|43,46|65,79|89,89|91,92|94,96|106,108|144,149|151,152|154,156|173,179|183,184|189,190|200,213|221,221|224,225|227,227|229,231|233,234|244,251|253,254|259,262 ?E------------------EEEE------------EEE?TT?STTT?--------------???EEEEEETTTTSGGGT??-----??B?EE?TTS---------SEE-----------------------------------EEEEEE?TT?EEE----------------EEEEEES???SS????TT???-----?HHHHHHHHHHHGGG------?B??TT?S?EEE?SS---------SSEEEEEE?TT????TTTS 2B20|A PF11829.3_DUF3349_seed 24 111 !Q:15,15|18,20|35,35|37,37|51,52|57,65|68,68|76,77|80,80|82,82|97,104|107,109 Q:0,14|16,17|21,34|36,36|38,50|53,56|66,67|69,75|78,79|81,81|83,96|105,106|110,110 HHHHHHHHHHHHHHH?TT???HHHHHHHHHHHTTT-S?HHHHHHHHHHHHH--HTSS--------?SS?HHHHHHS??SS?S?HHHHHHHHHHHGGG?-----??SS???S 2LKY|A PF11838.3_ERAP1_C_seed 123 501 !Q:0,0|8,8|11,11|16,16|27,38|46,46|49,49|67,76|80,80|90,94|97,101|104,113|135,136|146,148|157,157|162,164|167,179|181,181|198,199|202,202|210,210|220,222|224,224|227,230|232,242|257,261|265,269|280,280|282,307|321,323|330,330|338,347|351,355|359,359|368,380|382,382|400,400|407,412|414,414|419,420|433,451|464,465|467,477|480,483|487,489 Q:1,7|9,10|12,15|17,26|39,45|47,48|50,66|77,79|81,89|95,96|102,103|114,134|137,145|149,156|158,161|165,166|180,180|182,197|200,201|203,209|211,219|223,223|225,226|231,231|243,256|262,264|270,279|281,281|308,320|324,329|331,337|348,350|356,358|360,367|381,381|383,399|401,406|413,413|415,418|421,432|452,463|466,466|478,479|484,486|490,500 ?EEESGGG?SS?EEEE-ETTHHHHHHH------------HHHHHGG-GS?HHHHHHHHHHHHHHHHT----------TSS?HHHHHHHTT-----GG-----GT???-------HHHHHHHHHHHHHHHHHHHHS??HHHHHHHHH---HHHHTTHH-HHHH?-?SS??-----------S?HHHHHHHHHHHHHHHH--TT?HHHHHHH-HHHHHHHHH---T-TT?---S--------???HHHHHHHHHHHTTS-----HHH-----HHHHHHHHHH?S--------------------?-----HHHHHHHHHHHTT???HHHHHH-HHHHHHH-----?----SSS?----GGG-HHHHHHHH-------------H-HSTTHHHHHHHHHHHHH-HHHHHH------S?TTSH--HHHHHHHTTTTT?-------?----------SHHHHHHHHHHH--H-----------HS?---SSS???HHHHHHHHHHH 4FYS|A PF11844.3_DUF3364_seed 40 64 !Q:0,3|6,12|14,16|39,43 Q:4,5|13,13|17,38|44,63 ????TT-------S???HHHHTTSHHHHHHHHHHHHHHT???-?HHHHHHHHHHTTSHHHHHHH 2AFK|B PF11852.3_DUF3372_seed 37 201 !Q:3,4|6,7|11,13|29,30|32,32|36,38|59,59|64,65|79,79|83,84|94,97|101,109|112,115|127,127|131,131|134,134|137,137|139,142|145,146|149,151|154,154|160,160|162,164|170,171|177,182|189,189|200,200 Q:0,2|5,5|8,10|14,28|31,31|33,35|39,58|60,63|66,78|80,82|85,93|98,100|110,111|116,126|128,130|132,133|135,136|138,138|143,144|147,148|152,153|155,159|161,161|165,169|172,176|183,188|190,199 TSS??S-?SSS???HHHHGGGHHHHHHHH--H?GGG???HHHHHHHHHHHHHHHHHHTT?GGGG??SHHHHHHHEEESS?STT??TTEEEEEEE?-??SSS?--------SS????SSEEEEEEEEE?SSS?EE-EE?G----GG?-SS-??EE?HHHHT?S--?TTGGG?-EEEGG------GTEEEE?TTEEEEEEEE? 2FHF|A PF11858.3_DUF3378_seed 33 84 !Q:0,0|5,8|22,22|24,24|27,28|49,49|65,71|74,75|77,80|82,83 Q:1,4|9,21|23,23|25,26|29,48|50,64|72,73|76,76|81,81 ?EEEE-???HHHHHHHHHHSTT?B?SS??TTEEEEEEETTEEEEEETTS?EEEESTTHHHHHHTT------?TT??B????S?? 2D0C|A PF11890.3_DUF3410_seed 64 113 !Q:2,5|13,13|16,19|32,33|42,44|46,46|52,59|74,82|86,86|89,96|98,98|101,101 Q:0,1|6,12|14,15|20,31|34,41|45,45|47,51|60,73|83,85|87,88|97,97|99,100|102,112 GT????SEEEEEE?TT??--HHHHHHHHHHHH??THHHHHHH---H-HTTSS-------?HHHHHHHHHHHHHT??---????GGG?EE--------E?TT?HHHHHHHHHHT 3OET|A PF11892.3_DUF3412_seed 49 125 !Q:13,14|18,19|22,24|30,34|41,42|44,44|48,48|69,69|80,80|85,85|87,87|106,106|109,109|114,117|122,124 Q:0,12|15,17|20,21|25,29|35,40|43,43|45,47|49,68|70,79|81,84|86,86|88,105|107,108|110,113|118,121 HHHHHHHHHHHTT??SSS??SS???HHHHS?????HHHHHT??B?SSS?HHHHHHHHHHHHHHHHHHHH?HHHHHHHHHH?SEEE?B?HHHHHHHHHHHHHHHHTT?SS?SSSS????SEEE-?? 3GH1|A PF11894.3_DUF3414_seed 32 2733 !Q:0,2|15,19|22,24|29,30|40,44|47,49|51,51|53,54|63,76|82,82|86,86|90,91|108,108|118,119|122,123|126,137|139,139|163,163|165,170|172,177|188,213|239,252|258,259|261,267|280,289|309,310|313,313|329,330|332,339|357,402|409,409|429,452|456,456|483,484|487,488|495,497|506,518|533,538|542,542|545,547|550,550|556,557|560,562|564,564|568,625|627,631|637,672|687,687|706,706|708,714|717,783|807,807|809,811|817,817|821,821|824,825|829,859|869,870|876,876|887,889|906,920|923,923|943,987|1008,1009|1011,1011|1019,1029|1034,1034|1045,1056|1058,1059|1064,1100|1109,1120|1141,1173|1179,1188|1197,1198|1215,1217|1220,1220|1224,1224|1227,1227|1230,1231|1234,1234|1241,1266|1269,1271|1281,1284|1294,1295|1299,1299|1324,1324|1327,1331|1335,1365|1373,1374|1381,1381|1398,1399|1402,1416|1450,1486|1489,1490|1494,1496|1499,1505|1516,1517|1531,1531|1548,1861|1863,2732 Q:3,14|20,21|25,28|31,39|45,46|50,50|52,52|55,62|77,81|83,85|87,89|92,107|109,117|120,121|124,125|138,138|140,162|164,164|171,171|178,187|214,238|253,257|260,260|268,279|290,308|311,312|314,328|331,331|340,356|403,408|410,428|453,455|457,482|485,486|489,494|498,505|519,532|539,541|543,544|548,549|551,555|558,559|563,563|565,567|626,626|632,636|673,686|688,705|707,707|715,716|784,806|808,808|812,816|818,820|822,823|826,828|860,868|871,875|877,886|890,905|921,922|924,942|988,1007|1010,1010|1012,1018|1030,1033|1035,1044|1057,1057|1060,1063|1101,1108|1121,1140|1174,1178|1189,1196|1199,1214|1218,1219|1221,1223|1225,1226|1228,1229|1232,1233|1235,1240|1267,1268|1272,1280|1285,1293|1296,1298|1300,1323|1325,1326|1332,1334|1366,1372|1375,1380|1382,1397|1400,1401|1417,1449|1487,1488|1491,1493|1497,1498|1506,1515|1518,1530|1532,1547|1862,1862 ???SHHHHHHHHHHH-----TT???HHHH--HHHHHHHHT-----TT???S?B??STTHHHHH--------------TSEEE?SSS?EEE??HHHHHHHHHHHHHTTB?TTHHHHHHH--HS??ST------------T?HHHHHHHHHHHHHHHHHHHHHHS?S------S-----?HHHHHHHHTS--------------------------HHHHHHHHHHHHHHHHHHHHHHHHH--------------HHHHT--T??----?HHHHHHHHHHHH----------HHHHHHHHHHHHHHHHHHS?-TT?SSHHHHHHHHHHHHT--S-------?TTBGGGGGGHHHHHHHH----------------------------------------------TTGGGS?HHHHHHHHHHHHHHTTSGG------------------------GGG?HHHHHHHHHHHHHHHHHHTTSTTTTT--TT??HHHHTH---HHHHHHHH-------------TTHHHHHHHHHHTT----??GGG?TT???SS?HHHHH??SS???B?GGG??????????????????????????????????????????????????????????S?????HHHHH------------------------------------HHHHHHHHHHHHHH-HHTHHHHHHHHHHHHHHS?S-------SS???----------------------------------------------------------------HHHHHHTTHHHHHHHHHHHHHTT?H---HHHTH-HHH?SS--SHH-------------------------------HHHHHHHTT??SHHHH-HHHHHHHHHH??-SHHHHHHHHHHHHSSS---------------SS?HHHHHHHHHHHHHHHHHHT???????????????????????????----------------??HHHHHHHHHHHHHHHHHHHH--S?HHHHHHH-----------HHHH-HHHHHHHTTS----------??T--THHH-------------------------------------HHHHHHHH?----------?SSGGGGHHHHHHHHHHHHTT-----------------------------????SSHHH----------HHHHHHHH??SHHHHHHHHHHHHHHT???SB?TTS?SB?TT??SS?TTTTTT--------------------------TS---SBSSHHHHH----HHHHTTGGG--GGG?SSHHHHHHHHHHHHHHHHHHHHSS?TH-----HHH???????----????????----------??HHHHHHH?-THHHHH-HHHTSHHHHHHHHHHH--HS??????????---??TTHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHH-------------------------------------HH??TTB???TT????--?HHHHHHHHTT??HHHHHHHHHHHSS?HHHHHHHHHHHHHHHT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T?------------------------------------?----------------------------------------------------------------------------------------------------------------?------------------------?---------------------------------------------------------------------------------------------------------------------------??------------------------------------------------------------------------------------------------???----------------------------------------?----------------------------------------------------------------------------------------------------?-------------------------------------------??--------------------------------------------------------------------------------------------------------------------------------------------------------------------------???-----------------?-------------------------------------------------------------------------------------------- 4IFQ|A PF11895.3_DUF3415_seed 35 84 !Q:18,19|26,26|31,37|39,44|46,46|49,50|55,59|63,68|70,83 Q:0,17|20,25|27,30|38,38|45,45|47,48|51,54|60,62|69,69 HHHHHHHHHHHHHHHTTT??GGGSEE?GGGS???????S?---??B?TT??GGGB?-???TTS??????B?????????????? 2E39|A PF11896.3_DUF3416_seed 88 257 !Q:2,2|5,5|12,12|19,19|26,26|35,36|40,41|50,61|64,71|73,99|101,101|103,105|109,112|116,116|124,125|139,139|157,159|178,178|180,184|187,190|199,199|206,208|212,212|217,219|225,225|236,239|245,248|255,255 Q:0,1|3,4|6,11|13,18|20,25|27,34|37,39|42,49|62,63|72,72|100,100|102,102|106,108|113,115|117,123|126,138|140,156|160,177|179,179|185,186|191,198|200,205|209,211|213,216|220,224|226,235|240,244|249,254|256,256 SS?SS?EEEEES?BGGGTB?EEEETT?EEEEEEEE??SSS??EEEEEEEE-----------?TT?------?B?--???---------------------B?E---ESS----TTS?EEEEEEE??SSEEEEEEEEEEE?HHHHHHHHHHHHHHHTS---SHHHHHHHHHHHHHHHHH-T??---SH----HHHHHHHH-HHHHHH?--TTS?HHHH---HHTTS?HHHHHHHHHS???-EEEEE-???EEEEEE?G 3ZST|A PF11919.3_DUF3437_seed 32 128 !Q:2,2|19,19|21,22|25,40|50,50|57,57|59,60|79,81|86,86|93,94|97,98|105,105|107,123|127,127 Q:0,1|3,18|20,20|23,24|41,49|51,56|58,58|61,78|82,85|87,92|95,96|99,104|106,106|124,126 HH?HHHHHHHHHHHHHHTT?S??SS??--------------THHHHHHHH-HHTTSS-S-?SSHHHHTHHHHHHHHHHT---STTH-HHHGGG??SS--TTGGGS-S?-------------???TTB? 1VSY|5 PF11924.3_DUF3442_seed 50 390 !Q:0,67|70,73|80,80|82,82|84,85|95,99|104,106|108,108|112,112|123,126|128,128|143,145|147,147|149,151|156,156|166,168|174,174|178,178|186,186|201,201|203,206|209,209|212,212|214,214|216,216|218,239|241,241|244,246|262,266|277,277|281,282|284,284|287,287|289,291|294,294|298,298|310,310|319,322|325,325|328,328|332,332|339,342|352,353|359,359|365,368|370,371|376,376|382,386|388,389 Q:68,69|74,79|81,81|83,83|86,94|100,103|107,107|109,111|113,122|127,127|129,142|146,146|148,148|152,155|157,165|169,173|175,177|179,185|187,200|202,202|207,208|210,211|213,213|215,215|217,217|240,240|242,243|247,261|267,276|278,280|283,283|285,286|288,288|292,293|295,297|299,309|311,318|323,324|326,327|329,331|333,338|343,351|354,358|360,364|369,369|372,375|377,381|387,387 ------------------------------------------------------------?---????EE----EEEEEE?T-T??EEEEEEEEE-----EEEE---E?SSE-EEEEEEEEEE----E-TTEEEEEEEEEEEE---E-E---TTEE-EEEEEEEEE---ETTTT-EEE-EEEEEEE-EETTEEEEEEEEEE?S??--EE?SS?T-T?E----------------------E-EE?-?EEEEEEEEEETTEEE-----EEEEEEEEEE?SSS--B?TT?T---TS?BSS?EEEEEEEEEEE-ETTEEEEE----EE-EE?GGG?EEEEEE----EEEEEETTS-?HHHHT?GGGHH----H--HTSH-HHHTT-????S?? 4E1T|A PF11934.3_DUF3452_seed 35 196 !Q:1,28|30,30|39,40|42,43|55,62|69,85|112,151|170,170|172,172|176,177|196,196 Q:0,0|29,29|31,38|41,41|44,54|63,68|86,111|152,169|171,171|173,175|178,195 T???-------------------------S?HHHHHHHH--T??HHHHHHHHHHS?-----??HHHHHH-----------------HHHHHHHHHHHHHHHHHHHHHHTTTB???-------------????--------------??????HHHHHHHHHHHHHHHHHH-H?SSS??HHHHHHHHHHHHHHHHHH- 4ELJ|A PF11935.3_DUF3453_seed 30 353 !Q:3,3|5,6|32,36|39,40|61,61|64,64|66,67|69,90|109,111|114,126|130,130|133,135|140,140|143,143|146,147|150,150|162,162|170,170|173,195|206,236|244,244|248,250|264,264|266,274|278,278|299,299|305,306|318,320|324,325|333,352 Q:0,2|4,4|7,31|37,38|41,60|62,63|65,65|68,68|91,108|112,113|127,129|131,132|136,139|141,142|144,145|148,149|151,161|163,169|171,172|196,205|237,243|245,247|251,263|265,265|275,277|279,298|300,304|307,317|321,323|326,332 HHT?S--SHHHHHHHHHHHHHHHHHHHHHHHH----?SS??HHHHHHHHHHHHHHHHHHHG-GG?S-?H----------------------HHHHHHHHHHHHHHHHTS???TT????---------GGG-TT???GGGS?TT?SS??HH-HHHHHHHHHHH-HHHHHHT?TT---------------------??HHHHHHHHHH-------------------------------HHHHHHH?GGG---HHHHHHHHHHHHH-S?-------?TTS?HHHHHHHHHHHHHHHHHHHT-SGGGG--GGHHHHHHHHH---HTT??HHHHHHT???--????--????????? 3GS3|A PF11939.3_DUF3457_seed 38 257 !Q:0,0|3,4|18,20|24,29|32,33|40,48|52,54|56,56|59,64|70,70|73,73|81,88|91,91|95,98|101,101|106,108|111,112|122,128|140,143|146,147|165,171|173,176|178,249|251,256 Q:1,2|5,17|21,23|30,31|34,39|49,51|55,55|57,58|65,69|71,72|74,80|89,90|92,94|99,100|102,105|109,110|113,121|129,139|144,145|148,164|172,172|177,177|250,250 ?SS??HHHHHHHHHHHTT???GGG????-?SS??EEEEEE---------EET---T-EE------EEEEE?SS?EEEEEEE-----?--SS?EEE?-??TT?EEEE?-?TT??EEEEEEEET-------TTEEEEEEEEE????TT??HHHHHHHHHHHHHHHHT-------S????S?---------------------------------------------------?---------??-???-???S????-? 2KC5|A PF11940.3_DUF3458_seed 177 531 !Q:4,7|16,18|23,28|30,41|50,51|53,53|55,55|57,59|61,67|70,84|87,91|94,96|102,102|104,107|116,130|132,133|138,139|143,144|147,147|151,155|166,166|193,203|206,216|218,222|224,224|234,236|238,241|245,247|257,262|270,274|276,277|279,280|309,310|313,319|321,322|324,331|350,353|359,359|364,365|375,379|381,384|400,401|403,410|413,414|418,422|434,434|448,452|454,458|461,463|472,472|477,478|481,481|496,496|502,502|505,505|522,522 Q:0,3|8,15|19,22|29,29|42,49|52,52|54,54|56,56|60,60|68,69|85,86|92,93|97,101|103,103|108,115|131,131|134,137|140,142|145,146|148,150|156,165|167,192|204,205|217,217|223,223|225,233|237,237|242,244|248,256|263,269|275,275|278,278|281,308|311,312|320,320|323,323|332,349|354,358|360,363|366,374|380,380|385,399|402,402|411,412|415,417|423,433|435,447|453,453|459,460|464,471|473,476|479,480|482,495|497,501|503,504|506,521|523,530 TTTE----EEEEEEEE???BTTB------S--?----?????EEEEEEEE-?T-T-S--?B----???EE---------------TT-----EE??-SEEEE?S----SEEEEEES--??---?-------S??EEEE--STT??SS?EEE?-???HHHHHHHHHH?SSHHHHHHHHHHHHHHHHHHHHHHHH-----------TT--??---????H-----H-HHHHHHHHH---H?---SSS--?HHHHHHHTS?---??HHHHHTT?----S--S??HHHHHHHHHHHHHHHHHHTHHHHHHHHH--HT?-----?S--S??-----?SHHHHHHHHHHHHHHHHH----HTSSH-HHHH--HHHHHHHHH?----S----SHHHHHHHHHHHHHT--T----?---TT--HHH-----HHHHHHHHHTT?HHHHHHHHHHHHT???--T-----TH---HHHHHHHT-TSTT??TT?HHHHHHHHHHHHHH?HHHHT?TT?HHHHHHHHHHHHHHHH?HHHHHHHH 3KED|A PF11941.3_DUF3459_seed 120 143 !Q:19,24|26,27|30,30|46,52|56,62|66,66|71,71|74,76|78,78|81,95|104,125|130,130|132,136 Q:0,18|25,25|28,29|31,45|53,55|63,65|67,70|72,73|77,77|79,80|96,103|126,129|131,131|137,142 HHHHHHHHHHHHTHHHHTT?----?S??EE-EEEEETTEEEEEEEE-------TTE-------EEE-EEEE?SS---S?EE??----------???SEEEEEES???-------------------SSEE?T-----TEEEEE 2BXY|A PF11953.3_DUF3470_seed 133 61 !Q:3,5|16,17|20,24|26,27|29,35|43,47|49,49|51,51|55,55|57,60 Q:0,2|6,15|18,19|25,25|28,28|36,42|48,48|50,50|52,54|56,56 GTH---HHHHHHHHHT--TS?----B??S??--???TTHHHHT-----T?S?GGG-G-??? 1FER|A PF11962.3_Peptidase_G2_seed 19 278 !Q:2,2|10,10|13,16|24,32|41,43|55,60|63,63|75,78|80,82|84,84|90,91|98,99|102,108|112,112|114,114|120,123|126,126|131,131|133,133|137,137|139,139|145,151|153,160|163,163|165,172|177,177|179,179|182,183|187,192|196,196|213,213|216,217|220,220|225,226|230,230|232,237|244,246|248,249|258,260|265,265|271,274|277,277 Q:0,1|3,9|11,12|17,23|33,40|44,54|61,62|64,74|79,79|83,83|85,89|92,97|100,101|109,111|113,113|115,119|124,125|127,130|132,132|134,136|138,138|140,144|152,152|161,162|164,164|173,176|178,178|180,181|184,186|193,195|197,212|214,215|218,219|221,224|227,229|231,231|238,243|247,247|250,257|261,264|266,270|275,276 TT?EEEEEES?EE?--?TTEEEEE---------BSSEEEEE---ETTTTEEEESS??????SS?EEEEEEEBGGG????T---T?EEEEE--TTEEEE??TT??---??EEE?S?EEEEE????SS?GGGB?B?TTS?B?EEEEE------?S--------SS?E--------EEEE?B?TT??TTS?--???TTT?SSEEEEEEEEEEEEEE?TT??TT-SEEE--EET-T------EEEEES---B--SEEEEEEE???TTTS?EEEEE----EE? 3SUC|A PF11964.3_SpoIIAA-like_seed 151 136 !Q:3,3|9,10|14,14|21,21|30,30|34,36|39,40|47,47|50,51|55,55|57,57|59,59|64,74|76,76|79,83|91,92|95,97|107,114|122,123|125,125|135,135 Q:0,2|4,8|11,13|15,20|22,29|31,33|37,38|41,46|48,49|52,54|56,56|58,58|60,63|75,75|77,78|84,90|93,94|98,106|115,121|124,124|126,134 EEE-EEEEE--EEE?HHHHHH-HHHHHHHH-HTT???SS??EEEEEE-EE--EEE?T-T?GGGG?--???----?T-TS??---EEEEEEE??SS-??TTTTTGGGG-?-----?EEEEEEE--S?HHHHHHHHH? 2OOK|A PF11967.3_RecO_N_seed 154 97 !Q:0,8|20,20|24,24|42,42|46,46|51,53|58,58|64,65|72,78|82,82|86,86|94,97 Q:9,19|21,23|25,41|43,45|47,50|54,57|59,63|66,71|79,81|83,85|87,93 ?---??---SEEEEEEEEEE?SSS?EEEEEEETTTEEEEEEE-TTT-TSTT--?SHHH-HSSTT??EEEEEE------?SSS-EEE-EEEEEES???- 1U5K|A PF11969.3_DcpS_C_seed 99 197 !Q:4,6|11,24|27,28|31,36|40,40|46,46|49,57|60,66|70,70|77,77|80,96|98,100|105,117|120,120|141,156|160,161|170,172|177,177|187,188|191,191|193,194|197,197 Q:0,3|7,10|25,26|29,30|37,39|41,45|47,48|58,59|67,69|71,76|78,79|97,97|101,104|118,119|121,140|157,159|162,169|173,176|178,186|189,190|192,192|195,196 HHHH---HHHT????--????----SE--EE??----TTT?EEEEE?TT-------??SS------?STT?EEEEEE-SS-----------------S???SGGG------?-----?GG-GHHHHHHHHHHHHHHHHHHH??-------------?GGG--EEEEEESS?--SSSS?EEEEEETTS??TT?B--TT- 4EGU|A PF11971.3_CAMSAP_CH_seed 27 86 !Q:0,0|3,3|10,11|38,38|43,43|45,46|49,49|69,71|76,77 Q:1,2|4,9|12,37|39,42|44,44|47,48|50,68|72,75|78,85 ?TT?STTSTT??HHHHHHHHHTSHHHHHHHHHHSTTSS?GGGS?S??SS?HHHHHHHHHHHHHHHHHTT???TTTS??HHHHHTTS 3F7P|A PF11975.3_Glyco_hydro_4C_seed 8 262 !Q:22,22|26,26|41,43|48,49|65,65|74,75|90,90|126,126|129,130|134,134|139,140|156,156|158,158|160,162|164,164|176,178|187,187|195,195|214,216|219,221|246,247|261,261 Q:0,21|23,25|27,40|44,47|50,64|66,73|76,89|91,125|127,128|131,133|135,138|141,155|157,157|159,159|163,163|165,175|179,186|188,194|196,213|217,218|222,245|248,260 GGEEEEEEEETTEEEEEEEEET-TEE?HHHHHHHHHHTGGG???SSTT??TTSHHHHHHHHHHSS?EEGGGTTS??GGGGSSHHHHHHHH?TTTTSTTSHHHHHHHHHHHHHHHHHHHHHHHHHHH?TT??GGG?SSSS??SHHHHHHHHHHHHHH?T-T???S?SHHHHHHHHHH???EEEEEEEE?TTSSTTS?TTSEEEEEEEEETTEEEE???SS???HHHHHHTHHHHHHHHHHHHHHHHH??HHHHHHHHHTSTT? 3U95|A PF11976.3_Rad60-SLD_seed 42 81 !Q:0,2|6,6|10,13|16,19|22,23|29,29|37,39|41,45|56,58|61,62|68,69|72,72|74,75 Q:3,5|7,9|14,15|20,21|24,28|30,36|40,40|46,55|59,60|63,67|70,71|73,73|76,80 ???EEE?SSS?--?EE????TT??THHHH-HHHHHTT???T-----TTEEEEBTTB???SS??TTTTT??TT?E--EEEEE 2FCS|A PF11977.3_RNase_Zc3h12a_seed 28 249 !Q:0,0|2,3|12,12|15,20|23,28|34,39|52,53|59,61|70,71|75,93|97,97|100,100|110,113|121,126|128,136|138,138|152,152|156,157|159,161|167,173|175,175|185,210|214,215|219,227|233,234|237,237|240,240|244,245 Q:1,1|4,11|13,14|21,22|29,33|40,51|54,58|62,69|72,74|94,96|98,99|101,109|114,120|127,127|137,137|139,151|153,155|158,158|162,166|174,174|176,184|211,213|216,218|228,232|235,236|238,239|241,243|246,248 ?B??EEEEHHHH-HH------HH------TTTTS------EEHHHHHHHHHH--HHHTT???EEEEEEGG--GGS??----------------?TTS?EE?THHHHHHHH----TTSEEEE?-----B?????????B?HHHHHHHHHHHTT?EEE-?S???HHHHH-------H?HHHHHHHHH--------------------------HEE??EEE---------TTEEE??SS-TT?SSS??HHH 3V34|A PF11978.3_MVP_shoulder_seed 20 135 !Q:2,2|12,12|15,16|29,30|35,35|38,40|71,71|89,110|112,112|115,115|119,119 Q:0,1|3,11|13,14|17,28|31,34|36,37|41,70|72,88|111,111|113,114|116,118|120,134 SS?EEEEEEEEE?TT??EEEEEEEEEEEE??TTTT?HH---HHHGGGSSSSHHHHHHHHHHHHHHHHHTTS?HHHHHHHHHHHHHHHSS???????????????????---S?EE?TTT?EEEEEEEEEEEEESS 2ZUO|A PF11979.3_DUF3480_seed 8 380 !Q:0,2|23,23|37,37|40,41|45,45|48,50|52,55|58,58|65,65|69,74|76,76|79,79|108,109|117,123|126,126|135,135|139,145|156,158|163,166|174,183|196,197|212,213|216,235|244,247|249,249|252,254|256,256|260,261|263,263|271,278|284,284|295,312|338,339|348,348|351,351|362,364 Q:3,22|24,36|38,39|42,44|46,47|51,51|56,57|59,64|66,68|75,75|77,78|80,107|110,116|124,125|127,134|136,138|146,155|159,162|167,173|184,195|198,211|214,215|236,243|248,248|250,251|255,255|257,259|262,262|264,270|279,283|285,294|313,337|340,347|349,350|352,361|365,379 ???SSSEEEEEEEETTTHHHHHH?HHHHHHHHHHHHT?SS??SEE?TT???S????TT?GGGGTS?SSS??????B?TT?EEEEETTEEEEEEEGGGHHHHHHHHHTS-?SSEEEEE???---?TT?SEEEEEEE?TTS------?EEEEEEESSS???SSEE---?SEEEEES??????????EEEEETTEEEEE??HHHHHHHHHHHHTT??EE??????------??????-?EEEEEEES????S?TT--?B?TTT??B?TTSEEEE?--?????EEETT-EEEEEEEEEE??????-???????????HHHHHHHHHHHHHHGGGHHHHHHTT??EEEEEEEE?SS?EEEEEEETTB???GGGHHHHHHHHHHHH 4BKW|A PF11987.3_IF-2_seed 243 137 !Q:0,5|7,22|24,26|28,28|52,56|59,59|70,70|72,72|82,82|84,85|87,93|100,101|103,103|107,107|116,121|124,124|127,130|132,134|136,136 Q:6,6|23,23|27,27|29,51|57,58|60,69|71,71|73,81|83,83|86,86|94,99|102,102|104,106|108,115|122,123|125,126|131,131|135,135 ?-----S?????????---??--S---S?EEEEEEEESSHHHHHHHHHHHTT??--?SS?EEEEEEEEES?B?HHHHHHHHH-H--T------?EEEESS??B?TTH-HHHHHTTT---???EE?TT????S???S? 1G7T|A PF11988.3_Dsl1_N_seed 7 365 !Q:0,36|75,75|93,93|100,100|134,134|141,141|153,155|170,170|175,176|185,187|208,208|221,221|231,232|242,249|269,269|305,305|327,327|330,334|343,343|359,364 Q:37,74|76,92|94,99|101,133|135,140|142,152|156,169|171,174|177,184|188,207|209,220|222,230|233,241|250,268|270,304|306,326|328,329|335,342|344,358 ????????????????????-?????-??????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHH?TTGGGS?HHHHHHHHHHHHHHHHHHHHHHHHHHHTTTEEE?SSEEEE?SEEEETTTTEE---EEHHHHHHHHHHHH?TTSS??TTSHHHHT???HHHHHHHHHHHHHHHHHHTS?HHHHHHHHTTTT?TTEEEEEET--TTTEEEEEE????????HHHHHHHHHHHHHHHHHSS?HHHHHHHHHHHHHHHHHHHHHHHHHTHHHHTSSTT?THHHHHHHHHHHHHHHHHHHT?SS?????HHHHHHHH?HHHHHHHHHHHHHHH?????? 3ETV|A PF11989.3_Dsl1_C_seed 5 306 !Q:0,36|71,71|89,90|92,92|107,109|112,112|152,154|177,181|206,208|227,228|234,234|253,254|271,271|284,286|303,305 Q:37,70|72,88|91,91|93,106|110,111|113,151|155,176|182,205|209,226|229,233|235,252|255,270|272,283|287,302 ??????????--?????--------------------EEEETHHHHHHHHHHHHHHHHHTTTTTSSHHHHH-HHHHHHHHHHHHHHHHH?-S?HHHHHHHHHHHHHH--?TT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSSS???HHHHHTHHHHHHHTHHHHHHTT---??HHHHHHHHHHHHHTTHHHHHHTSS???HHHHHHHHHHHHHHHHHT??GGGTT?HHHHHHHHHHHHHHHHHT??HHHHHHHHHTTGGGGS?HHHHHHHHHHHS???HHHHHHHHHHHHHHHH??? 3K8P|C PF11991.3_Trp_DMAT_seed 53 529 !Q:5,6|24,26|46,46|48,58|62,66|69,71|75,76|85,92|96,98|105,106|108,108|110,111|117,117|122,124|138,139|142,145|157,158|161,162|176,187|189,198|207,210|214,215|223,229|239,242|258,262|280,302|305,305|312,312|318,318|320,320|323,325|327,328|336,336|338,338|351,351|355,358|360,360|369,369|376,376|380,391|394,417|419,421|424,438|446,447|449,456|458,459|462,462|464,470|476,478|480,493|496,496|508,508|514,516|523,523 Q:0,4|7,23|27,45|47,47|59,61|67,68|72,74|77,84|93,95|99,104|107,107|109,109|112,116|118,121|125,137|140,141|146,156|159,160|163,175|188,188|199,206|211,213|216,222|230,238|243,257|263,279|303,304|306,311|313,317|319,319|321,322|326,326|329,335|337,337|339,350|352,354|359,359|361,368|370,375|377,379|392,393|418,418|422,423|439,445|448,448|457,457|460,461|463,463|471,475|479,479|494,495|497,507|509,513|517,522|524,528 HHHHH--HHHHHHHHHHHHHHHTT-??HHHHHHHHHHHHHHTGGGB?S??--------?SSS?????TT---STT??SEEEEEET--------TTT---EEEEEE??B?T--TBTST-TBTT?-?STHHHHHHHHGGG-?TT?-??HHHHHHHHHHS??HH--HHHHHHHTGGGTT------------T????-----?EEEEEEEE----TTE--EEEEEEE------?THHHHHHHT-?-?HHHHHHHHHHHHHHH?----GGGHHHHHHHHHHHHHT?----------------------TT?SEEEEE-EEEES-S?TT---T??EEEEEEE?E-ESHHHHHHHHTT-TTT??--S-HHHHHHHH-HHHHHH-HHH??--------??EE?-------------------????S???TT????????-------EEEEEEE-?T--------T?-SS?E-------EEEEE??-T--------------TS?HHHHHHHHHHH-HHHTT--?HHHHHH-HHHHH 4E0T|A PF11999.3_DUF3494_seed 43 299 !Q:7,7|12,15|19,19|21,21|23,23|29,29|33,34|39,42|45,45|50,50|53,55|73,79|96,106|111,113|115,115|121,122|127,128|131,131|134,134|136,139|143,147|150,150|153,156|162,163|168,175|178,179|186,188|190,190|194,195|198,205|211,214|217,218|225,229|234,236|240,240|243,243|254,258|262,266|269,274|278,278|286,287|294,294 Q:0,6|8,11|16,18|20,20|22,22|24,28|30,32|35,38|43,44|46,49|51,52|56,72|80,95|107,110|114,114|116,120|123,126|129,130|132,133|135,135|140,142|148,149|151,152|157,161|164,167|176,177|180,185|189,189|191,193|196,197|206,210|215,216|219,224|230,233|237,239|241,242|244,253|259,261|267,268|275,277|279,285|288,293|295,298 EEESSEE-EEES?--?EEE-S?E-EESSS?GGG--EESS?--?EE?TTSS?EE---ETTEEEEEEETTSSTTH-------HHHHHHHHHHHHHHHH-----------HHHT??-S?SEESG--GGGB?-TT?EE?S----EEE-----EE-SS?---EEESS-?EEEE--?----?TT??EEEEES---S?EEE?-TT?-------BEEEE----TT??GGGEEE-----EESS?--EEE?TT?EEEEEEEESS---?-EEE----?TT-----?EEE-EEEEESS--EEEEES?EEEE 3UYV|A PF12002.3_MgsA_C_seed 278 205 !Q:2,2|18,19|36,36|40,40|58,58|67,68|79,82|98,100|102,108|115,151|153,154|156,159|162,162|166,185|189,190|203,204 Q:0,1|3,17|20,35|37,39|41,57|59,66|69,78|83,97|101,101|109,114|152,152|155,155|160,161|163,165|186,188|191,202 TT?HHHHHHHHHHHHHTT??HHHHHHHHHHHHHHTT-GGG?TTHHHHHHHHHHHHHHT?HHHHHHHH--HHHHHHHHHS????HHHHHHHHHHHHHHH---S?????-?GGGSSS?????????----????????????----????????S--S?---GG-GTT-----??-------?????-SST--THHHHHHHHHHH?? 3CTD|A PF12003.3_DUF3497_seed 32 355 !Q:7,8|11,11|13,13|23,27|30,33|59,71|77,122|153,153|158,159|182,185|188,189|196,196|208,208|211,215|219,230|233,234|241,241|249,249|251,290|293,295|312,313|316,322|325,325|327,328|333,334|337,340|343,343|345,345 Q:0,6|9,10|12,12|14,22|28,29|34,58|72,76|123,152|154,157|160,181|186,187|190,195|197,207|209,210|216,218|231,232|235,240|242,248|250,250|291,292|296,311|314,315|323,324|326,326|329,332|335,336|341,342|344,344|346,354 HHHHHTT??HH-H-HHHHHHHHT-----TS-???HHHHHHHHHHHHHHHHHHHHHHHHT?????????????HHHHH----------------------------------------------HHHHHHHHHHHHHHHHHHTSGGGHHHHTTS?HHHH--HHHHHHHHHHHHHHHHHHHTTS---?SS--EEEEEE?SSEEEEEEEEE?SS????-EEE??----------SS??SEEEEE?HHHHHHT?B----------------------------------------TT---EEEEEEEEESSGGGGS??TT?????--SS?B??SSTT??SE----EE?S?EEEEEESST 4DLO|A PF12007.3_DUF3501_seed 22 207 !Q:0,3|8,10|45,46|63,64|80,82|93,94|108,108|123,125|128,128|131,131|135,135|141,141|143,144|153,154|164,166|168,175|181,182|186,186|192,194|205,206 Q:4,7|11,44|47,62|65,79|83,92|95,107|109,122|126,127|129,130|132,134|136,140|142,142|145,152|155,163|167,167|176,180|183,185|187,191|195,204 ????GGGS??-HHHHHHHHHHHHHHHHHHHTTTEEEETTTEEEEE??HHHHHHHHHHHHHHHT??SHHHHHHHHHHHGGG???SSEEEEEEEE??SSHHHHHHHHHHT-TTGGGSEEEEETTS?-?EE?EE?TTS?HHHHH-S??SEEEEEEE??HHHHHHHHT---T??------EEEEE??TTS?EEEEE-??HHHHHHHHTT?? 3FJV|A PF12008.3_EcoR124_C_seed 79 396 !Q:3,5|12,12|15,15|19,20|23,24|36,38|40,48|52,54|79,79|82,82|92,93|96,97|109,110|121,133|151,177|180,185|191,396 Q:0,2|6,11|13,14|16,18|21,22|25,35|39,39|49,51|55,78|80,81|83,91|94,95|98,108|111,120|134,150|178,179|186,190 HHB???HHHHHH?EE?TTT??EE??HHHHHHHHHHH???S---------SSS--?SHHHHHHHHHHHHHHHHHHHHHTT?HH-HHHHHHHSS??SS??HHHHHHHHHTT??HHHHHHGGGS??---------??HHHHHHHHHHHHHHHHT?????????????---------??-??TT???--?HHHHH????-----------????????????---------??????????--??????????--????????????????????----------??????????????????????????????????----?????????????---??????????????------?????????------?????-----????????????????- 3EVY|A PF12009.3_Telomerase_RBD_seed 54 198 !Q:13,16|19,27|31,31|33,42|52,52|62,62|64,64|67,69|77,78|82,82|84,84|87,87|89,90|93,95|98,119|130,136|145,145|161,167|173,174|193,194|196,197 Q:0,12|17,18|28,30|32,32|43,51|53,61|63,63|65,66|70,76|79,81|83,83|85,86|88,88|91,92|96,97|120,129|137,144|146,160|168,172|175,192|195,195 HHHHHHHHHHHHH----HS--------?HHH-H?---------SHHHHHHHH-HHHHHHHHH-T?TT???HHHHSTT??GGG?G-GG?S??SS???HH----------------------HHHHHHHHHH-------HHHHHHHH-THHHHHHHHHEEEES----?--SSSTT??EEEEHHHHHHHHHHHHHH--S?? 3DU5|A PF12019.3_GspH_seed 214 257 !Q:18,19|21,21|24,24|30,30|33,35|41,49|51,51|55,60|64,64|67,67|70,71|78,78|89,114|116,163|165,165|170,173|179,206|209,210|213,219|226,227|229,242|250,255 Q:0,17|20,20|22,23|25,29|31,32|36,40|50,50|52,54|61,63|65,66|68,69|72,77|79,88|115,115|164,164|166,169|174,178|207,208|211,212|220,225|228,228|243,249|256,256 HHHHHHHHHHHHHHHHHH--H-SS?EEEEE?SS--?EEEEE??-------S?SSS??---?EES?SS?TT--TSSSTT?SSEEEEEESS---------------------?????S------------------------------------------------S?SEEE--?-TTSBB--------------------------??EE--EE-------EEETTT??E--------------EEEEEES------S 4DQ9|A PF12026.3_DUF3513_seed 14 266 !Q:0,139|173,174|203,204|237,237|239,239 Q:140,172|175,202|205,236|238,238|240,265 ????-?????????????????????????????????????????????---------------------------------??????????????????????--????---------????????---?????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHHHHHHHHHHHHS??SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT?S?HHHHHHHHHHHHHHHHHHHHHHHHHH 3T6G|B PF12032.3_CLIP_seed 120 72 !Q:1,2|4,5|7,7|9,10|15,15|19,19|26,26|30,34|36,38|48,49|51,51|53,62|65,65|67,68 Q:0,0|3,3|6,6|8,8|11,14|16,18|20,25|27,29|35,35|39,47|50,50|52,52|63,64|66,66|69,71 E??T--T?S-?EEEE?TTT?HHHHHH-HHH-----S???HHHHHHHHH--T?S--??-----?SS-S??EEE 2XXL|A PF12041.3_DELLA_seed 20 82 !Q:0,0|8,10|17,17|33,44|47,47|52,52|55,57|69,81 Q:1,7|11,16|18,32|45,46|48,51|53,54|58,68 ?HHHHTTT???BGGGHH-HHHHHHHHHHHHHTT?-????-?????TT-GGGS?TT?--HHHHHHHHHHH??-?-???????? 2ZSI|B PF12042.3_RP1-2_seed 17 187 !Q:0,5|11,11|15,21|29,29|37,37|47,49|70,73|92,92|95,95|117,120|126,126|145,159|178,179|185,186 Q:6,10|12,14|22,28|30,36|38,46|50,69|74,91|93,94|96,116|121,125|127,144|160,177|180,184 ??????SSSSS?SSH-------HHHHHHH-HHHHHTT?THHHHHHHT???HHHHHHHHHHHHHHHHHHHS?--?THHHHHHHHHHHHHHTTT-TS?HHHHHHHHHHHHHHHHTTTTS??--SSSHH-HHHHHHHHHHHHHHHHHH---------------HHHSTHHHHHHHTTTTTT??SSSSS?? 2K3O|A PF12047.3_DNMT1-RFD_seed 38 193 !Q:0,5|15,16|19,19|22,23|33,39|46,46|49,93|99,102|104,112|119,126|128,128|134,134|137,137|142,143|145,145|155,156|158,158|173,173|175,178|180,181|192,192 Q:6,14|17,18|20,21|24,32|40,45|47,48|94,98|103,103|113,118|127,127|129,133|135,136|138,141|144,144|146,154|157,157|159,172|174,174|179,179|182,191 ??????EEEEEEEEE?-TT?BB??SSSSTTTTT???----EEEEEE-EE??------???--------------?????--------------?EEEEE----E??------?SEEEEE???--???B?EEEEE?SS?EEEE??B?TTTHHHHTT??H-HHHHHHHHHHHHHH?T----T??HHHHHHHHHH? 3EPZ|A PF12052.3_VGCC_beta4Aa_N_seed 8 59 !Q:0,41 Q:42,58 ???????????????????????-----------------??THHHHHHHHHHHHHTTS 4DEX|A PF12053.3_DUF3534_seed 7 176 !Q:3,3|20,21|27,35|48,50|53,54|62,63|66,67|69,70|80,81|84,84|93,175 Q:0,2|4,19|22,26|36,47|51,52|55,61|64,65|68,68|71,79|82,83|85,92 EEE-EEEETTEEEEEEEETS??BHHHH---------HHHHHHHHHHHH???TT??EEEEEEE-?TT??B??TTSBHHHHS?-TT?EEEEEEEE-------------------?-----------------------------?--------------------------------- 2NS5|A PF12058.3_DUF3539_seed 17 104 !Q:0,3|19,28|38,39|45,46|49,59|65,65|85,85|96,97|103,103 Q:4,18|29,37|40,44|47,48|60,64|66,84|86,95|98,102 ????EEEETTTEEEEEEEE??-----???EEEEETTTT??EEEEE??SS?---------?EEEEE?HHHHHHHHHHHHHHHHHHS?HHHHHHHHHH--HHHHH? 2XKO|C PF12066.3_DUF3546_seed 19 117 !Q:0,0|8,8|13,14|52,54|84,103|108,116 Q:1,7|9,12|15,51|55,83|104,107 ?HHHHGGG-TTTS??HHHHHHHHHHHHHHHHHHHHHHHHHHHTTSHHHHHHH--?HHHHHHHHHHHHHHHHHHHHHHHHHHHTT???---------------??SBSS????????? 3AX1|A PF12095.3_DUF3571_seed 23 91 !Q:0,7|9,13|19,19|23,23|28,28|44,44|49,50|56,58|70,72|76,76|87,90 Q:8,8|14,18|20,22|24,27|29,43|45,48|51,55|59,69|73,75|77,86 ????---?S?????EEEEE-SSS?SEEE?HHHHHHHHHHHHHHS?TTTS-?HHHHH???HHHHHHHHHHH???EEE-ETTEEEEEEE???? 2KRX|A PF12102.3_DUF3578_seed 18 208 !Q:13,35|37,40|44,44|57,57|61,62|65,65|71,71|73,74|76,77|100,101|104,104|108,109|111,115|118,121|133,162|165,165|175,175|179,185|206,207 Q:0,12|36,36|41,43|45,56|58,60|63,64|66,70|72,72|75,75|78,99|102,103|105,107|110,110|116,117|122,132|163,164|166,174|176,178|186,205 HHHHHHHHHHHHH?----------------------S????SSS?SEETTEEEEEES?SSS??SS?EEEEE?T--T??SSSSEEEEEEEEGGGTEEEEEE--EE?SSS??S?????SS????BHHHHHHHHHS?---------------------------??SS?TTSEEEEEE?GGG-??---?HHHHHHHHHHHHHHHHHHHT?? 3SSE|A PF12103.3_Lipl32_seed 4 201 !Q:7,7|18,18|22,23|43,43|54,55|59,62|65,65|68,68|75,75|83,86|94,94|96,97|104,104|110,111|121,123|126,128|133,134|141,144|147,147|156,157|161,161|163,163|178,180|192,192|194,195|200,200 Q:0,6|8,17|19,21|24,42|44,53|56,58|63,64|66,67|69,74|76,82|87,93|95,95|98,103|105,109|112,120|124,125|129,132|135,140|145,146|148,155|158,160|162,162|164,177|181,191|193,193|196,199 EEEEEEE?SEEEEEEEEE?TTS??SEEETTTEEEEEEEEEESS?BSEEEEEEES??TTT????TT?EE?HHHHHS?TTTTSTT????EEEEEEE?S??SGGGHH-HHHHS??SEEEEEESS???SS???SSSS??EEEEEE--??SS?SSTTGGGS??GGG?B?SEEEEEEEEESSSS???EEEEEEEEESS?S??TTTS? 3FRL|A PF12104.3_Tcell_CD4_Cterm_seed 5 28 !Q:0,1|3,3|17,17|19,23|25,27 Q:2,2|4,16|18,18|24,24 ??S?SHHHHHHHHHHTT?S?????S??? 2JKT|P PF12105.3_SpoU_methylas_C_seed 53 60 !Q:11,13|16,16|31,46|48,52|54,59 Q:0,10|14,15|17,30|47,47|53,53 HHHHHTTTTSS?--SS?HHHHHHHHHHHHHH----------------H-----H?????? 1ZJR|A PF12106.3_Colicin_C_seed 12 36 !Q:0,0|10,10|19,20|30,30 Q:1,9|11,18|21,29|31,35 ?EEEEEEEEE?GGGSTTTT??EEEEEEEEE-ETTEE 2FHZ|B PF12107.3_VEK-30_seed 8 17 !Q: Q:0,16 HHHHHHHHHHHHHHHHH 2KJ4|B PF12108.3_SF3a60_bindingd_seed 20 30 !Q:1,5|7,8|27,28 Q:0,0|6,6|9,26|29,29 S???--S??HHHHHHHHHHHHHHHHHS??S 2DT7|A PF12109.3_CXCR4_N_seed 4 34 !Q:0,30 Q:31,33 ??????????-????????????????????THH 3OE6|A PF12110.3_Nup96_seed 36 411 !Q:0,0|13,13|26,26|39,40|58,61|63,65|78,78|85,85|88,90|93,105|110,110|128,131|144,183|186,186|196,202|207,216|222,224|232,233|236,236|253,256|259,298|301,308|320,322|327,327|338,338|340,340|344,347|366,381|393,394 Q:1,12|14,25|27,38|41,57|62,62|66,77|79,84|86,87|91,92|106,109|111,127|132,143|184,185|187,195|203,206|217,221|225,231|234,235|237,252|257,258|299,300|309,319|323,326|328,337|339,339|341,343|348,365|382,392|395,410 ?HHHHHHHHHHTT?HHHHHHHHHHTT?HHHHHHHTTTTS??HHHHHHHHHHHHHHTTT?---S???HHHHHHHHHHTT?SSSSTT?GG---GG-------------GGTS?HHHHHHHHHHTTTTTTS---?HHHHHHHHHTTS??-------------------------------------?TT?HHHHHHHHH-------HTGG----------GHHHH---HHHHHTT??SS?HHHHHHHHHHHHTTSS????HH----------------------------------------HH--------HHHHHHHHHHH---HTTT?HHHHHHHHHT?S?HHH----HHHHHHHHHHTTTTGGGS----------------SHHHHHHHTTT??HHHHHHHHHHTTTTTT 3IKO|B PF12111.3_PNPase_C_seed 16 39 !Q:0,20|25,25|32,32|34,38 Q:21,24|26,31|33,33 ?????????????????????SSTT?SEEEEE?S????? 3GME|D PF12112.3_DUF3579_seed 19 111 !Q:0,9|21,21|23,23|25,25|37,37|40,44|48,55|59,60|66,68|73,74|85,85|106,106|109,110 Q:10,20|22,22|24,24|26,36|38,39|45,47|56,58|61,65|69,72|75,84|86,105|107,108 ????----??EEEEEEEETTS?B?S?TTHHHHHHHTT?EE----?SSS--------SEE??TTEEE??-BTTB??EEEETHHHHH?HHHHHHHHHHHHHHTEEEEE-SS?? 2L9D|A PF12116.3_SpoIIID_seed 19 86 !Q:0,0|3,6|22,24|35,35|51,51|85,85 Q:1,2|7,21|25,34|36,50|52,84 ?TT----HHHHHHHHHHHHHHH???HHHHHHHHTS?HHHHHHHHTTHHHHH?HHHHHHHHHHHHHHHHTHHHHHHHHHHHHHHSS? 2L0K|A PF12120.3_Arr-ms_seed 15 105 !Q:0,0|8,10|13,13|16,16|18,19|21,21|27,28|30,30|32,32|50,54|58,59|69,70|73,73|84,84|87,87|94,94|102,104 Q:1,7|11,12|14,15|17,17|20,20|22,26|29,29|31,31|33,49|55,57|60,68|71,72|74,83|85,86|88,93|95,101 ?EEEEESS???TT?EE?S??B?SSSTT-?B?S?EEEESBHHHHHHHHHHS?----SSS??EEEEEEESS??EE?GGGSSSSSSS?TT?EEEESS?EEEEEEE??? 2HW2|A PF12121.3_DD_K_seed 14 30 !Q:0,1|3,3 Q:2,2|4,29 ??S?SHHHHHHHHHHHHHHHHHHHHHHHHH 2K9B|A PF12122.3_DUF3582_seed 32 125 !Q:0,6|24,46|48,49|66,66|68,70|72,72|78,124 Q:7,23|47,47|50,65|67,67|71,71|73,77 -??????SSHHHHHHHHHHHHHTT-?????-------??????????S-?GGGHHHHHHHHHHHHH?T---T?HHHHT??????????----------?---------?--?------------- 4HDD|A PF12123.3_Amidase02_C_seed 16 50 !Q:3,4|10,10|12,13|16,16|22,25|27,27|41,43|45,46 Q:0,2|5,9|11,11|14,15|17,21|26,26|28,40|44,44|47,49 HTT??EEEEE?T--TS?EEEEE????H-HHHHHHHHHHHHT---T??EEE 2L48|A PF12124.3_Nsp3_PL2pro_seed 5 66 !Q:19,22|41,41|46,47|55,56|65,65 Q:0,18|23,40|42,45|48,54|57,64 HHHHHHHHHHHHTEETTEE????EETTEEEEEEETTEEEEE?SSSS??EEETTEE??HHHHHHHH? 2KAF|A PF12125.3_Beta-TrCP_D_seed 6 40 !Q:7,7|23,23|39,39 Q:0,6|8,22|24,38 HHHHTTS?HHHHHHHHHHHHHTS?HHHHHHHHHHHGGGT? 2P64|A PF12134.3_PRP8_domainIV_seed 14 236 !Q:0,0|4,4|16,17|23,23|34,34|38,38|45,45|52,52|56,56|64,64|71,71|73,73|94,94|99,99|118,118|121,121|124,124|132,134|151,151|154,154|168,169|172,172|190,190|199,200|204,207|210,210|213,217 Q:1,3|5,15|18,22|24,33|35,37|39,44|46,51|53,55|57,63|65,70|72,72|74,93|95,98|100,117|119,120|122,123|125,131|135,150|152,153|155,167|170,171|173,189|191,198|201,203|208,209|211,212|218,235 ?EEE?TTTGGGGGSSS?-EEEEE?TTSSEEEEEE?SSS?EEEEEE?EEEEEE?TTT?EEEEEEE?GGGGTT?S?HHHHHHHHHHHHHHHHHHHS?GGGS?SEEEESSGGGHHHHHHHT-TT?TT?EEEEESS???GGGGGGSHHHHHHHHH?SS?EEEEEETTTTGGG--TS?HHHHHHHHHHHHHHHHH?HHHHHHHT??STT????TT?SS???-?HHHHHHHHHHHHHHHHHH 4JK7|A PF12135.3_Sialidase_penC_seed 23 25 !Q:0,0|3,4|14,15 Q:1,2|5,13|16,24 ?TT??EEEEEEEEE??TTTEEEEEE 2O4E|A PF12136.3_RNA_pol_Rpo13_seed 7 44 !Q:0,24|40,41 Q:25,39|42,43 ????????????????----?????TTHHHHHHHHHHHTT??SS 4B1P|J PF12137.3_RapA_C_seed 50 384 !Q:1,2|26,27|31,32|52,58|60,61|86,87|96,97|112,114|130,131|134,139|147,154|157,157|161,163|165,168|170,175|178,179|187,187|189,191|212,212|215,216|218,218|220,220|223,223|226,227|229,232|235,236|241,244|248,248|253,254|256,260|267,267|269,270|272,272|280,286|345,345|348,349|370,370|375,376|379,383 Q:0,0|3,25|28,30|33,51|59,59|62,85|88,95|98,111|115,129|132,133|140,146|155,156|158,160|164,164|169,169|176,177|180,186|188,188|192,211|213,214|217,217|219,219|221,222|224,225|228,228|233,234|237,240|245,247|249,252|255,255|261,266|268,268|271,271|273,279|287,344|346,347|350,369|371,374|377,378 S??EEEEEEETTSHHHHHHHHHHHTT??SSS??SSHHHHHHHHHHHHHHHHH--??---S??TTHHHHHHHHHHHHHHHHHHHHTT??TTHHHHTT??HHHHHHHHHHTTTT?-?HHHHHHHHHHHHHTT??EE----??SSSEEEE??-----?SS?SSS?-?S??--S---???EE??HHHHHTS?S???SSSTTHHHHHHTHHHHSSTT?EE??S?S?TT?SS??S????EE??EEEE????GGG?TTTT??S?????EESSSS?B??S?SHHHHTT???????SSSSGGGTTTTHHHHHHHHHHHHHSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?SS??THHHHHHHHHHHHHHHHHTT?EEEE??EE????? 3DMQ|A PF12139.3_APS-reductase_C_seed 43 109 !Q:1,3|7,8|11,11|18,18|22,23|30,30|34,35|43,44|47,47|50,55|61,68|70,70|74,75|78,78|80,94|97,99|102,107 Q:0,0|4,6|9,10|12,17|19,21|24,29|31,33|36,42|45,46|48,49|56,60|69,69|71,73|76,77|79,79|95,96|100,101|108,108 E???TTT??SS?EEEEEE?SSE--EEEEEE?TTS-?EEEEEEE??SS?TT---???SSTTS??---???T-TSS??TT?S?----------????SS???EE??????S 1JNZ|B PF12142.3_PPO1_DWL_seed 39 62 !Q:0,3|9,9|12,12|16,17|19,20|22,23|34,35|44,51|54,61 Q:4,8|10,11|13,15|18,18|21,21|24,33|36,43|52,53 ????HHHHT?EE-EEE-?T--T??EEEEEHHHHT?-GGGGTEEE-????--?TT?????--- 2P3X|A PF12143.3_PPO1_KFDV_seed 32 153 !Q:0,0|3,5|9,9|12,12|17,20|29,30|34,34|48,48|50,50|59,59|64,100|110,111|121,121|124,148 Q:1,2|6,8|10,11|13,16|21,28|31,33|35,47|49,49|51,58|60,63|101,109|112,120|122,123|149,152 ?EE---EEE-EE-EEEE???-HHHHHHHT??TTS?EEEEEEEEEETTE-E-EEEEEEEE-EGGG??---?????????????????????-------????EEEEEEEEE??HHHHHHTTS?TT?------------------------EEEE 3DDV|A PF12146.3_Hydrolase_4_seed 137 137 !Q:1,1|5,5|9,9|11,15|17,18|20,26|33,33|35,38|40,40|42,44|47,48|50,51|55,55|63,63|72,73|78,78|81,92|94,98|100,101|104,110|112,112|115,116|119,120|122,122|124,125|127,127|132,134 Q:0,0|2,4|6,8|10,10|16,16|19,19|27,32|34,34|39,39|41,41|45,46|49,49|52,54|56,62|64,71|74,77|79,80|93,93|99,99|102,103|111,111|113,114|117,118|121,121|123,123|126,126|128,131|135,136 S?EEE-EEE-E??---S--S?-----?SEEEEE-E-?-?T-T-??GG--G--GHH-HHHHHHH-TTEEEEEE??TTST-TS-----?------S-----S--TT---?--?S?TH--HH--H-H--H-HHHH---HH 4DGQ|A PF12148.3_DUF3590_seed 8 97 !Q:5,5|9,9|21,21|23,23|28,29|32,35|38,38|48,48|51,51|55,55|67,69|73,73|77,78|81,81|88,88|95,97 Q:0,4|6,8|10,20|22,22|24,27|30,31|36,37|39,47|49,50|52,54|56,66|70,72|74,76|79,80|82,87|89,94 EEEEE?TTT?EEEEEEEEEEE?S?SSSS??TT????SS?TTTSEEEEE?SS?GGG?EEEEETTTEEE???SEE?GGG??BT?EEEEEE?SSSTTS??- 2L3R|A PF12149.3_HSV_VP16_C_seed 2 30 !Q:0,2|7,8|20,25|28,29 Q:3,6|9,19|26,27 ???TTSS??THHHHHHHTTS??????SS?? 2PHE|C PF12150.3_MFP2b_seed 3 367 !Q:0,6|16,18|22,22|24,24|27,27|30,30|65,65|71,71|79,80|82,82|88,88|106,106|109,110|122,122|126,126|136,136|157,157|164,164|167,168|171,172|180,188|190,190|192,192|203,204|210,210|216,220|223,224|226,227|245,245|263,264|267,268|276,277|304,305|307,308|311,312|319,319|353,353|357,357|365,365 Q:7,15|19,21|23,23|25,26|28,29|31,64|66,70|72,78|81,81|83,87|89,105|107,108|111,121|123,125|127,135|137,156|158,163|165,166|169,170|173,179|189,189|191,191|193,202|205,209|211,215|221,222|225,225|228,244|246,262|265,266|269,275|278,303|306,306|309,310|313,318|320,352|354,356|358,364|366,366 ???????EEEEEETTS???SSB?B?TT?SS?EEEEEEETTEEEEEEEEEETTEEEEEEEETTEEE?SHHHH?SEEEEEE??S?HHHHS?EEEEEEGGGHHHHHHTT?EE??BTTEEEEEETT?TTS?EEEEEETTT?EEEEEETTEEEEEEGGGGTT?EEEEEE?SS??TT??SHHHHTS????--???B?S?EEEEEETTSB??SSSEE?BGGGS?????TT??S??EEEEEEETTEEEEEEEE-EETTEEEEEEEETTEEE?-SS??EEEEEEE??TTTBSEEEEEEEHHHHTTGGGSSEEE??B??TT??BEEEEE-EETTEEEEEEEETTTTEEEEEETTEEEEEEGGG-GTT?EEEEEEE?T 2BJQ|A PF12151.3_MVL_seed 16 44 !Q:18,19|33,37 Q:0,17|20,32|38,43 HHHHHHHHHHHHHHTTSE--EEEEEEEEETTTE-----EEEEEE 1ZHQ|A PF12152.3_eIF_4G1_seed 20 83 !Q:0,1|3,7|11,14|25,25|27,33|38,40|43,45|55,59|62,64|76,79 Q:2,2|8,10|15,24|26,26|34,37|41,42|46,54|60,61|65,75|80,82 ??S?????TTS-???HHHHHHHHHT?B??---??GGGS???SS???SSTTGGGSS----?SS???HHHHHHHHHHH????SSH 1RF8|B PF12153.3_CAP18_C_seed 11 30 !Q:25,26 Q:0,24|27,29 HHHHHHHHHHHHHHHHHHHHHHHHH--HHH 2K6O|A PF12160.3_Fibrinogen_aC_seed 12 83 !Q:0,0|2,8|10,18|22,22|31,31|46,46|50,51|54,55|58,59|61,72|77,78|81,81 Q:1,1|9,9|19,21|23,30|32,45|47,49|52,53|56,57|60,60|73,76|79,80|82,82 ?S???--??S---??????BSS?EEEEEEEE-ETTTEEEEEEEEEB?SSS??BT--TB-?S?-----?????-SSSS??SS?T 2JOR|A PF12161.3_HsdM_N_seed 142 293 !Q:9,9|13,13|16,22|27,29|50,53|63,77|80,80|83,85|87,87|90,90|94,99|109,110|114,114|123,133|135,146|149,149|151,153|156,167|170,170|172,173|176,200|208,220|229,233|235,245|247,252|256,256|258,270|274,277|279,281 Q:0,8|10,12|14,15|23,26|30,49|54,62|78,79|81,82|86,86|88,89|91,93|100,108|111,113|115,122|134,134|147,148|150,150|154,155|168,169|171,171|174,175|201,207|221,228|234,234|246,246|253,255|257,257|271,273|278,278|282,292 HHHHHHHHH-HTT?TT--?---?HHHH---HHHHHHHHHHHHHHHHHHHH----HHHHHHHTT------------???TT?SS???G-GG?SSH------HHHHHHHHH--HHT?THHHHTTT????------?T------------TT?H---HH------------HH-H??SS???????????????????------HHHHHHH-------------HHHHHHHH----?G-----------G------GSS?S-----------??SSS----S???HHHHHHHHHHH 3UFB|A PF12162.3_STAT1_TAZ2bind_seed 8 25 !Q:1,3|8,10|12,12 Q:0,0|4,7|11,11|13,24 S???STTS???S?HHHHHHHHHHHT 2KA6|B PF12163.3_HobA_seed 15 192 !Q:0,0|15,16|30,31|33,33|48,48|50,50|57,57|73,73|75,76|79,84|91,95|100,100|102,103|105,105|120,120|128,130|143,143|151,152|155,156|159,160|163,163|191,191 Q:1,14|17,29|32,32|34,47|49,49|51,56|58,72|74,74|77,78|85,90|96,99|101,101|104,104|106,119|121,127|131,142|144,150|153,154|157,158|161,162|164,190 ?EEHHHHHHHHHHHH--HHHHHHHTTGGGG??S?HHHHHHHHHHHHHT-T?EEEEEE?GGGHHHHHHHHHHHS?S??TT??-???EEESTT-----STTS?S--S?HHHHHHHHHHHBSS-EEEEEES???SHHHHHHHTSSS?EEEEESS??SS??EE??TT?TTHHHHHHHHHHHHHHHHHHHHTTSEE? 2UVP|A PF12164.3_SporV_AA_seed 17 99 !Q:0,1|9,9|15,16|42,42|47,56|73,74|82,82|84,84|92,98 Q:2,8|10,14|17,41|43,46|57,72|75,81|83,83|85,91 ??EEEEEEE?SEEEE?-SSEEEGGGTEEEEESSHHHHHHHHT?EEEE?---??????EEEEEHHHHHHHHHHH-?SSEEEEE?S?SEEEEEE??????? 3G74|A PF12169.3_DNA_pol3_gamma3_seed 52 147 !Q:1,1|10,11|14,14|28,28|43,45|68,71|75,80|95,95|133,136|138,138|142,147 Q:0,0|2,9|12,13|15,27|29,42|46,67|72,74|81,94|96,132|137,137|139,141 B?HHHHHHHS??SS?THHHHHHHHHHTT?HHHHHHHHHHHHHH???THHHHHHHHHHHHHHHHHTTSS????GGG------TTTHHHHHHHHHHS?HHHHHHHHHHHHHHHHHGGGSSSHHHHHHHHHHHHHH----T?SSS?????- 1XXH|B PF12170.3_DNA_pol3_tau_5_seed 5 142 !Q:0,3|5,5|22,22|33,34|49,49|58,58|65,66|84,85|92,94|98,99|123,123|125,141 Q:4,4|6,21|23,32|35,48|50,57|59,64|67,83|86,91|95,97|100,122|124,124 ????S?SSHHHHHHHHHHHHHH?HHHHHHHHHT??SHHHHHHHTEEEEE?SSEEEEEE?GGGTTT??HHHHHHHHHHHHHHHSS??EEEEEE???TTS??HHHHHHHHHHHHHHHHHHHHHHT?S??--------------- 2AYA|A PF12171.3_zf-C2H2_jaz_seed 140 32 !Q:2,2|8,8|10,10|18,19|26,27 Q:0,1|3,7|9,9|11,17|20,25|28,31 EE?BTTTT-B?BSSHHHH--HTTSSS--HHHH 4DGW|A PF12172.3_DUF35_N_seed 158 50 !Q:7,8|13,13|17,18|20,23|25,25|28,30|34,35|39,39|41,41|43,46|48,49 Q:0,6|9,12|14,16|19,19|24,24|26,27|31,33|36,38|40,40|42,42|47,47 HHHHHTT??EEEE?TTT??E----E-ES??-SEE--TTT-T-E----E?? 3IRB|A PF12175.3_WSS_VP_seed 3 219 !Q:0,17|19,33|48,48|68,69|83,84|87,88|96,96|104,105|107,111|113,115|119,120|124,125|131,131|135,135|146,156|160,163|165,165|171,172|176,176|179,179|184,184|192,194|211,218 Q:18,18|34,47|49,67|70,82|85,86|89,95|97,103|106,106|112,112|116,118|121,123|126,130|132,134|136,145|157,159|164,164|166,170|173,175|177,178|180,183|185,191|195,210 -----------------?H---------------HHHHHHHHHHHHHT?EEEEEEEEEEETTTTEEEE??EEEEETTTEEEEE?-TT??HHHHTTS?SSEEEEE??S---??S???GGG??EEE??EEEEE?SSS?EEEEEEEEEE??--------?TTS????S?EEEEE??EEE?TT?EEEE?EEEEESS???SGGGTTEEEEEEEEES?--??--- 2EDM|A PF12176.3_MtaB_seed 9 465 !Q:0,5|7,7|15,16|37,37|42,43|45,48|78,79|87,88|117,118|127,130|132,132|135,135|137,137|140,140|159,160|165,167|181,181|213,213|218,219|232,232|236,237|240,240|263,264|266,266|268,268|271,271|282,284|296,298|300,300|308,308|313,316|318,319|349,349|354,355|367,367|391,391|412,412|416,419|437,437|439,439|455,455|458,459 Q:6,6|8,14|17,36|38,41|44,44|49,77|80,86|89,116|119,126|131,131|133,134|136,136|138,139|141,158|161,164|168,180|182,212|214,217|220,231|233,235|238,239|241,262|265,265|267,267|269,270|272,281|285,295|299,299|301,307|309,312|317,317|320,348|350,353|356,366|368,390|392,411|413,415|420,436|438,438|440,454|456,457|460,464 ??????S?SSSSGGG??SSEEEEEEEETBTEEEEESS?EEEE??B--??GGGGSSHHHHHHHHHHHHHHHHHHHHHHT??EEEEEEE??HHHHHSHHHHHHHHHHHHHHHHHHHHHH??EEEEEEEE????B?SS?B?TT-STTHHHHHHHHHHHHHTT??EEEE???TTHHHHHHHHTTT?HHHHHHHHHTHHHHHHHHHHHHHHHHHHHHT?EEEE??GGGTHHHHHHHH?STT??SS?HHHHHHHHHHHHHHHHHHHHTT??S?B?TT?TTHHHHHHHH???BEEESGGGTTT???S?TTGGGTT?SEEE????B??EETTEEHHHHHHHHHHHHHHHHHHHHHTT?HHHH--HHHHHHHHHTT?HHHHTTSHHHHHHHHHHHHTTTT?HHHHHHHHHHHHHHHHHHHH-HTT????HHHHHHHHHHHHHHHTS?S?HHHHHHHHHHHHHHH?TT??GGGGT 2I2X|A PF12177.3_Proho_convert_seed 3 41 !Q:0,0|5,5|7,7|19,21|24,24|40,40 Q:1,4|6,6|8,18|22,23|25,39 ?SSSS?S?SSHHHHHHHHT???SS?SSTTHHHHHHHHTTT? 2KDT|A PF12178.3_INCENP_N_seed 7 38 !Q:0,0 Q:1,37 ?SSTTHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHH 2QFA|C PF12179.3_IKKbetaNEMObind_seed 9 38 !Q:0,0|28,28|33,34 Q:1,27|29,32|35,37 ?HHHHHHHHHHHHHHHHHHHHHHHHTTS?GGGS??GGG 3BRV|A PF12180.3_EABR_seed 6 35 !Q: Q:0,34 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 3E1R|A PF12181.3_MogR_DNAbind_seed 4 149 !Q:11,12|28,29|52,52|64,64|83,84|98,98|103,103|120,120|123,123|126,129|131,148 Q:0,10|13,27|30,51|53,63|65,82|85,97|99,102|104,119|121,122|124,125|130,130 HHHHHHHHHHS??TTHHHHHHHHHHHHT??HHHHHHHHHHHHHHHHHHHHTT?HHHHHTSSEEE?HHHHHHHHHHHHHHHHTT??HHHHHHHHSTTTT?SSSS?HHHHHHHHHHHHTTSS?SS?EE????S????------???????? 3FDQ|A PF12182.3_DUF3642_seed 10 87 !Q:0,2|4,6|14,14|17,20|38,38|42,42|60,62|65,65|81,81|84,85 Q:3,3|7,13|15,16|21,37|39,41|43,59|63,64|66,80|82,83|86,86 ???S???EEEEEEE-TT----EEEEEEEETTEEEEEEE?TTS?EEEEEEEEETTTTEEEE---TT-EEEEEEEETTEEEEE?TT??G 3GE2|A PF12183.3_NotI_seed 13 332 !Q:6,6|10,13|24,25|35,39|41,41|45,45|47,48|53,68|73,74|78,79|81,82|96,97|101,101|105,106|127,127|137,139|142,144|147,148|153,154|157,157|171,171|182,186|189,189|203,213|224,233|278,281|284,284|288,290|295,302|305,305|308,308|318,318|320,326|329,331 Q:0,5|7,9|14,23|26,34|40,40|42,44|46,46|49,52|69,72|75,77|80,80|83,95|98,100|102,104|107,126|128,136|140,141|145,146|149,152|155,156|158,170|172,181|187,188|190,202|214,223|234,277|282,283|285,287|291,294|303,304|306,307|309,317|319,319|327,328 ESSSSB?SSS????HHHHHHHHHT??HHHHHHSSS?????S?GGG?S??EEEE??----------????EEEE??GGG--G??HHHHHHHHHHHTT??SSS?EEE??GGGGSSHHHHHHHHHHHHTT?EEEEEEETT---TT???EE??BTTB??EE?SEEEEEEEESSSS?EEEEEEEEEE?????SS?SHHHHHHHHHHHS???????????HHHHHHHHTT??-----???TTSSSTTTHHHHHHHHHSTTSTTEEEEEEEEEHHHHHHHHHHTT????EE?SSS--?EEES??------TT?SS?EEEEEEESS?S??----?SS??? 3BVQ|A PF12185.3_IR1-M_seed 4 65 !Q:0,0|7,10|22,23|35,45|56,64 Q:1,6|11,21|24,34|46,55 ?EEEEEE????HHHHHHHHHTT??TTGGGGGSSTT???????????HHHHHHTTTT????????? 3UIN|D PF12186.3_AcylCoA_dehyd_C_seed 7 115 !Q:15,18|46,47|78,79|107,108|112,114 Q:0,14|19,45|48,77|80,106|109,111 HHTHHHHHHHHTGGG????GGGHHHHHHHHHHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?-GGGHHHHHHHHHHHHHHHHHHHHHHHH??GGG??? 2OKU|A PF12187.3_VirArc_Nuclease_seed 4 204 !Q:0,18|45,45|47,48|50,65|84,87|99,100|102,102|107,120|137,137|140,140|171,173|175,175|178,186|195,195 Q:19,44|46,46|49,49|66,83|88,98|101,101|103,106|121,136|138,139|141,170|174,174|176,177|187,194|196,203 ???????????-???????HHHHHHHHHHHHHHHHHHHHHHHTSS?S??B????????????????TTGGGTTTSSEEEEEESS----SSEEEEEEEEE??S?SSTT?????-----????EEEEEHHHHHHHHHTT?GG-GEEEEEEETTTTEEEEEEHHHHHHHHHTTS---S?EE?????????EEEEEGGG?EETHHHHH 2W8M|A PF12188.3_STAT2_C_seed 5 57 !Q:0,0|3,9|16,17|27,28|34,34|37,37|46,48|54,56 Q:1,2|10,15|18,26|29,33|35,36|38,45|49,53 ?SS???????HHHHTS??TGGGGGTTS??TTTSS?SS?STTHHHHS-??GGGGT??? 2KA4|B PF12189.3_VirE1_seed 4 63 !Q:0,30|37,37|53,62 Q:31,36|38,52 ???????????????????????????????TTTTTS?HHHHHHHHHHHHHHT?????????? 3BTP|B PF12190.3_amfpi-1_seed 2 91 !Q:0,12|20,21|24,26|30,31|46,46|55,55|58,58|60,63|70,71|76,76|79,79|88,90 Q:13,19|22,23|27,29|32,45|47,54|56,57|59,59|64,69|72,75|77,78|80,87 --------?????TTHHHHS??SS???GGG??TTSEEEEEEESGGG?EEEEEEEE?TT?B????BTTTTB??SEEE?TT?EEETTEEE??? 3BT4|A PF12191.3_stn_TNFRSF12A_seed 2 130 !Q:0,36|54,54|57,60|66,69|71,71|73,76|79,129 Q:37,53|55,56|61,65|70,70|72,72|77,78 -------------------------------??????SSEEEETTTTEEEESTT?SS????TTTTT????S?S????SS??-----------------------------------??????????---? 2KN0|A PF12192.3_CBP_seed 5 59 !Q:0,0|26,29|38,39 Q:1,25|30,37|40,58 ?SSHHHHHHHHHHHHHHHHHHHHHHT????HHHHHHTT??HHHHHHHHSSSSTTTTHHH 2JV7|A PF12193.3_Sulf_coat_C_seed 3 69 !Q:9,10|32,32|53,55 Q:0,8|11,31|33,52|56,68 HHHHHHHHT??GGGHHHHHHHHHHHHHHHHHH?SSHHHHHHHHHHHHHHHHHH???HHHHHHHHHHHHS 3F2E|A PF12194.3_Ste5_C_seed 5 199 !Q:13,14|24,24|28,29|36,37|50,50|53,53|74,75|83,83|87,91|93,94|103,105|108,110|112,112|120,120|122,124|128,128|133,134|138,146|154,155|158,163|166,166|171,171|185,186|189,198 Q:0,12|15,23|25,27|30,35|38,49|51,52|54,73|76,82|84,86|92,92|95,102|106,107|111,111|113,119|121,121|125,127|129,132|135,137|147,153|156,157|164,165|167,170|172,184|187,188 HHHHHHHHHHHHT??SEEEEEEEE?GGG??STHHHH--HHHHHHHHHHHH?TT?EEEEEETTSBEEEEEEHHHH??SHHHHHG-GGG?????B??HHHHHHHH?--TT???S?EEEEEEE?S???TTT?GGGS??GGG?????????EEEEEES??SS??????SS?EEES?HHHHHHHHHHHTT??SS???--????? 3FZE|A PF12195.3_End_beta_barrel_seed 3 83 !Q:0,1|8,8|12,12|16,16|22,22|25,28|31,31|38,39|43,44|49,50|62,62|64,66|69,69|72,72|75,75|82,82 Q:2,7|9,11|13,15|17,21|23,24|29,30|32,37|40,42|45,48|51,61|63,63|67,68|70,71|73,74|76,81 ??EEEEES?EEE?TTS?EEEEE?TT????TT?EEEEES??STT??EEEE??EEEETTEEEEE?S???SS?EE?TT?EEEEEE? 1V0F|A PF12196.3_hNIFK_binding_seed 5 43 !Q:0,2|6,11|25,28|34,34|41,42 Q:3,5|12,24|29,33|35,40 ???TTS??????HHHHHHHHHHHHH?--?GGGGS?SEEESS?? 2AFF|B PF12197.3_lci_seed 4 46 !Q:0,1|9,13|43,46 Q:2,8|14,42 ??EEEEETT?????EEEETTEEEEEEEEEEETTTTEEEEEEES???- 2B9K|A PF12199.3_efb-c_seed 2 65 !Q:0,0|24,25|40,40|61,64 Q:1,23|26,39|41,60 ?HHHHHHHHHHHHHHHHHHHHHHH??HHHHHHHHHHHHHS?GGGHHHHHHHHHHHHHHHHH???? 2NOJ|B PF12200.3_DUF3597_seed 24 172 !Q:10,22|25,25|30,36|39,61|63,88|93,93|104,104|108,110|114,114|123,126|140,142|144,144|146,146|170,171 Q:0,9|23,24|26,29|37,38|62,62|89,92|94,103|105,107|111,113|115,122|127,139|143,143|145,145|147,169 HHHHHHHHHT----------???SS?TTTT???????SS??--------------------?S?--???????---------------?SSEE?HHHHHHHHHH-HSS???TTT?HHHHHHHT????SHHHHHHHHHHHT???S-S?HHHHHHHHHHHHHHHHHGGGSEE?? 2GQB|A PF12202.3_OSR1_C_seed 16 39 !Q:8,8|15,15|17,18|21,21|32,33 Q:0,7|9,14|16,16|19,20|22,31|34,38 EEEEEEES?TTSSSS-S??TT?EEEEEEETTT??HHHHH 2V3S|A PF12203.3_HDAC4_Gln_seed 6 100 !Q:0,2|68,99 Q:3,67 ???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTHHHHHHHTTTTGGG?????????????--------??????????? 2O94|A PF12204.3_DUF3598_seed 18 318 !Q:0,0|7,7|10,10|13,15|24,24|28,31|48,48|61,76|78,79|86,94|100,100|103,103|105,105|109,110|113,113|118,118|139,139|143,143|158,170|174,177|179,179|193,198|210,210|214,214|226,228|243,243|245,245|248,249|253,253|256,256|268,269|271,275|278,278|292,294|303,303 Q:1,6|8,9|11,12|16,23|25,27|32,47|49,60|77,77|80,85|95,99|101,102|104,104|106,108|111,112|114,117|119,138|140,142|144,157|171,173|178,178|180,192|199,209|211,213|215,225|229,242|244,244|246,247|250,252|254,255|257,267|270,270|276,277|279,291|295,302|304,317 ?HHHHHH-TT?EE---EEEEEEEE?TTS---?EEEEEEEEEEEEEETT-TTEEEEEEEETT----------------S??EEEEES???------TTEEE?TT-S?EEE??SB?BTTB?SEEEEEEEETTEEEEEEEEE?TTS?EEEEEEEEEEETTS----?????????GGG----T?EEEEEEEEEEETT?--???EEEEEEEEEEE?TTS?EEEEEEETTEE---EEEEEEEETTEEEE?S?TT??EEE-EE?GGGEEEEEESS??T-----TS?EEEEEEEEEETTE---EEEEEEEE?TTSBEEEEEEEEEE 2O62|A PF12205.3_GIT1_C_seed 5 125 !Q:0,0|3,3|7,7|9,9|35,35|58,58|62,63|87,89|91,91|94,94|97,97 Q:1,2|4,6|8,8|10,34|36,57|59,61|64,86|90,90|92,93|95,96|98,124 ?SS?BSS?S?HHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHTS?SSB??HHHHHHHHHHHHHHHHHHHHHHS???S?TT?SS?HHHHHHHHHHHHHHHHHHHHHHHHHHH 2JX0|A PF12206.3_DUF3599_seed 7 125 !Q:0,7|14,15|19,22|24,24|29,31|35,35|39,40|43,43|58,61|85,87|90,90|96,97|104,104|106,108 Q:8,13|16,18|23,23|25,28|32,34|36,38|41,42|44,57|62,84|88,89|91,95|98,103|105,105|109,124 ????????EEEEEE??EEE????B-TTTB???TTS?EEE??SS?SEEEEEEEEEEEEE----EEEETTTTEEEEEEEEEEEETTS???TT?EEEET--TEEEEE?S?-?EEETTEEEEEEEEGGG 3F3B|A PF12207.3_DUF3600_seed 6 162 !Q:0,16|40,40|63,63|67,67|69,69|74,74|98,100|106,106|129,129|132,134|139,139|161,161 Q:17,39|41,62|64,66|68,68|70,73|75,97|101,105|107,128|130,131|135,138|140,160 ?????????????????HHHHHHHHHHHHHHHHHHHHHHS?HHHHHHHHHHHHHHHHHHHHHB?TTS?B?GGGS?HHHHHHHHHHHHHHHHHHHHHTT???HHHHS?HHHHHHHHHHHHHHHHHHHHHT?SS???GGGS?HHHHHHHHHHHHHHHHHHHHH? 3FGG|A PF12208.3_DUF3601_seed 6 87 !Q:1,3|9,9|14,14|16,16|19,19|22,23|26,26|29,29|49,49|56,59|65,65|76,76|78,78|85,86 Q:0,0|4,8|10,13|15,15|17,18|20,21|24,25|27,28|30,48|50,55|60,64|66,75|77,77|79,84 T---TEETT?EEEE?S?EE?TT??EE?TT?EEEEEEEEEETTTTEEEEE-EETEEE----EEEEE?STTTTHHHHT?G-GGTEEE?? 3G1J|A PF12209.3_SAC3_seed 10 80 !Q:33,35|38,38 Q:0,32|36,37|39,79 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 3FWB|B PF12210.3_Hrs_helical_seed 5 97 !Q:25,26|30,30|91,91|95,97 Q:0,24|27,29|31,90|92,94 HHHHHHHHHHHHHHHHHHHHHHHHT??GGG?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHH??- 3F1I|H PF12211.3_LMWSLP_N_seed 19 295 !Q:0,0|25,25|35,35|41,42|45,47|52,52|59,59|75,76|79,79|92,96|112,115|117,117|121,121|123,124|126,127|130,133|137,137|140,142|146,149|151,151|154,154|166,166|169,169|175,176|182,187|191,191|194,207|210,211|216,218|220,223|226,227|230,230|234,234|240,240|249,250|255,258|266,266|277,295 Q:1,24|26,34|36,40|43,44|48,51|53,58|60,74|77,78|80,91|97,111|116,116|118,120|122,122|125,125|128,129|134,136|138,139|143,145|150,150|152,153|155,165|167,168|170,174|177,181|188,190|192,193|208,209|212,215|219,219|224,225|228,229|231,233|235,239|241,248|251,254|259,265|267,276 ?EEEEEEGGGHHHHHHHHHHHHHTT?EEEEEEEET-TEEEE--EE??-SSTT?HHHHHH-HHHHHHHHHHHHHHT??TT?EEEEEEEEEGGG?????HHHHHHHHHHHHTTT----T?EEE?B??S--SS?---EEE?SS-??TTS??-?B?SS?EEHHHHEEEEE?SS?BTTTB??EEEEE??-???EEE?TT?-------------SS??EEEE???S--??EE??TT-EEE?TTTTT?EEEESTTS??EEEE????EEESSSS?SEEEEEEEEE??????????????????- 3CVZ|A PF12212.3_PAZ_siRNAbind_seed 10 47 !Q:7,7|22,22|32,33|38,38|40,40|45,45|47,47 Q:0,6|8,21|23,31|34,37|39,39|41,44|46,46 HHHHTTT?HHHHHHHHHHSTTT?EEEETTSTT??EEEE?B?TTSS?B- 3DA5|A PF12213.3_Dpoe2NT_seed 10 73 !Q:0,0|17,17|20,20|35,35|54,55|61,61 Q:1,16|18,19|21,34|36,53|56,60|62,72 ?HHHHHHHHHHHHHHTT?EE?HHHHHHHHHHTTTS?TTTHHHHHHHHHHHHTTS??SSSEE?HHHHHHHHHHH 2V6Z|M PF12217.3_End_beta_propel_seed 3 460 !Q:6,9|15,16|19,20|42,42|56,59|64,66|72,77|82,82|84,84|104,105|116,118|125,125|129,129|133,133|139,139|142,145|148,148|155,156|160,161|166,167|179,179|181,183|186,186|189,189|192,192|199,199|204,205|210,211|213,213|216,223|232,232|236,236|238,239|246,246|251,251|264,264|267,268|273,274|278,278|301,301|305,307|319,319|324,324|327,329|332,334|348,348|353,353|358,362|365,365|367,368|380,384|387,389|395,395|398,399|403,405|426,426|428,431|439,440|446,449|458,458 Q:0,5|10,14|17,18|21,41|43,55|60,63|67,71|78,81|83,83|85,103|106,115|119,124|126,128|130,132|134,138|140,141|146,147|149,154|157,159|162,165|168,178|180,180|184,185|187,188|190,191|193,198|200,203|206,209|212,212|214,215|224,231|233,235|237,237|240,245|247,250|252,263|265,266|269,272|275,277|279,300|302,304|308,318|320,323|325,326|330,331|335,347|349,352|354,357|363,364|366,366|369,379|385,386|390,394|396,397|400,402|406,425|427,427|432,438|441,445|450,457|459,459 SEEEEE????SSEEE??TT??EEETTEEEEEEEEESSSSSTT?EEEEEEESSTTSS????EESS???TTTTT------EEEE?B?EEEETTEEEEEEEEEETTT??EEEEEEEEEE???EEEEES?EEE?TTS?EEEEE?TT????TT?EEEEES??STT??EEEE??EEEETTEEEEE?S???SS?EE?TT?EEEEEE?STTS??EEEE??S?TT-------?SEEEEEEE?SSS?E--EEEEEE?SSSS?EEEEEEETTTTT?TT??EEEE??GGG?TTEEEEEEEEETTEEEEEEEES?TTS???EEEEESSTTSS?EEEE?SS???SS???EEEETTEEEEEEE?SSTT?SSTT?????SS?B??EEEEEEEETTT?--??TT???EEEEE?BB??SSS???SEEEEEEEETTEEEEEEEEB?S????TTTTTTT??TTSTT????EEEEEEEE?S 1V0F|A PF12218.3_End_N_terminal_seed 5 67 !Q:0,2|8,8|20,20|23,24|27,27|30,30|37,39|46,46|51,51|56,57|62,62 Q:3,7|9,19|21,22|25,26|28,29|31,36|40,45|47,50|52,55|58,61|63,66 ???EEEEE?HHHHHHHHHHS?TT??EE?TT?EEEESS???GGGEES?EEEE?SSTT??EEEE?BTSS 1V0F|A PF12219.3_End_tail_spike_seed 5 160 !Q:0,2|4,8|11,11|13,15|19,20|23,23|27,27|31,31|33,33|37,37|39,44|53,55|67,67|76,78|81,81|85,85|101,101|120,120|129,129|138,139|146,146|149,149|155,156|159,159 Q:3,3|9,10|12,12|16,18|21,22|24,26|28,30|32,32|34,36|38,38|45,52|56,66|68,75|79,80|82,84|86,100|102,119|121,128|130,137|140,145|147,148|150,154|157,158 ???S?????EE?S???SSS??EE?TTS?EEE?S?EEE?S-----?EEESSEEE???BTTTTEEEEEE?BSEEEEEE???SS?GGG?EEEEESSSSSSGGGB?EEEEEBTTSSSTTEEEEE?SEEEEESS?EEESSSSS??BSBTTB?BS?BEESS??EE? 3GW6|A PF12226.3_Astro_capsid_p_seed 3 234 !Q:4,4|8,8|10,12|22,24|26,27|39,39|44,50|55,57|66,66|70,70|75,75|79,81|95,95|105,105|109,110|112,112|120,122|125,125|135,136|158,160|164,164|166,170|174,175|178,179|187,189|191,233 Q:0,3|5,7|9,9|13,21|25,25|28,38|40,43|51,54|58,65|67,69|71,74|76,78|82,94|96,104|106,108|111,111|113,119|123,124|126,134|137,157|161,163|165,165|171,173|176,177|180,186|190,190 SSSB?TTS?B???SSTTSEEEE???B??GGGEEEEEESS?EEEE???????EEEE???EEEEEEEE?TTT?EEEE?GGG???EEEEHHHHTTTTT?TTSTTEEEB?GGG??S?HHHHHHH???TT?EEEEEEETT??EEEEEEETTTTEEEEEEEESS???TTS?S?????EEE??TT??HHHHHHH???S??----------------------------------------- 3TS3|A PF12229.3_PG_binding_4_seed 117 159 !Q:0,5|9,13|21,22|33,33|35,36|46,50|54,57|63,63|67,70|79,84|89,89|94,96|101,101|103,107|112,114|118,122|125,129|133,134|139,141|153,153|155,155 Q:6,8|14,20|23,32|34,34|37,45|51,53|58,62|64,66|71,78|85,88|90,93|97,100|102,102|108,111|115,117|123,124|130,132|135,138|142,152|154,154|156,158 ----??HHH-----HHHHHHH??EEEEETTEEE-E??HHHHHHHEE-----EET----TEEEE?HHH----HHHHHHHH------HHHH?TTTS--?EEEE?S-----SSSE---EEE?-?-?SS?----EEE-?HHHH---HHHHHHHHHHT-S?EEE 1ZAT|A PF12241.3_Enoyl_reductase_seed 49 248 !Q:2,4|22,23|30,30|49,49|51,52|59,62|67,67|70,73|75,76|80,84|88,88|96,96|101,103|111,114|142,142|155,157|190,190|193,193|201,205|230,233 Q:0,1|5,21|24,29|31,48|50,50|53,58|63,66|68,69|74,74|77,79|85,87|89,95|97,100|104,110|115,141|143,154|158,189|191,192|194,200|206,229|234,247 SS???HHHHHHHHHHHHHHHTT??EEEEES?TTSHHHHHHHHHHHHHHS?S?-EEEEEE????SEEE?TT----T??EEE?????SSS?EEEEEEE-TTTT---EEEEEEE????HHHHHHHHHHHSSHHHHHHHHHHHHTT?EEEEEEEEEEEE???GGGHHHHTSHHHHHHHHHHHHHHHHHHHHHHT-TT?EEEEEEE?????TTGGGSTHHHHHHHHHHHHHHHTT????HHHHHHHHHHHTTT 4GGP|A PF12242.3_Eno-Rase_NADH_b_seed 44 94 !Q:0,4|11,14|32,34|36,38|41,45|48,54|60,60|75,75|78,79|86,90|92,92 Q:5,10|15,31|35,35|39,40|46,47|55,59|61,74|76,77|80,85|91,91|93,93 ?????EETTEE????HHHHHHHHHHHHHHHHH---H???TT?---?SE-------EEEES?SSHHHHHHHHHHHH-HH??EEEEEE?????B-T 4GGP|A PF12255.3_TcdB_toxin_midC_seed 22 181 !Q:8,8|17,17|20,29|35,35|49,50|52,52|54,55|57,59|73,73|75,75|77,77|81,81|92,92|96,96|105,111|114,122|125,129|133,133|140,141|143,144|163,163|167,175 Q:0,7|9,16|18,19|30,34|36,48|51,51|53,53|56,56|60,72|74,74|76,76|78,80|82,91|93,95|97,104|112,113|123,124|130,132|134,139|142,142|145,162|164,166|176,180 HHHHTTTT?EEEEEEEE?SS?---------GGGGS?SEEEEEEEEEEEE??S?S--S-??EEEEEEEEEEEEE?T-T?TTS?EEEEEEEEEE?TTS?EEEEEEEE???????SS--------?SS----?TTS?TTHHHH--T??GGGGEEEEEEEEEEEEEE?STT?-------?EEEEE 4IGL|A PF12256.3_TcdB_toxin_midN_seed 29 228 !Q:7,9|11,11|16,17|20,24|33,33|40,40|45,45|47,47|51,60|63,66|71,71|73,73|76,86|89,89|95,95|107,110|128,133|135,136|138,139|152,155|157,159|161,163|196,199|201,203|205,205|210,216|219,219|225,226 Q:0,6|10,10|12,15|18,19|25,32|34,39|41,44|46,46|48,50|61,62|67,70|72,72|74,75|87,88|90,94|96,106|111,127|134,134|137,137|140,151|156,156|160,160|164,195|200,200|204,204|206,209|217,218|220,224|227,227 EETTTEE?--S?EEEE??TT????-TTSEEEEE?TTSSSS?EEEE-E?SSS----------SS---?EEEE?S?SS------?----TT?EEEEE?SSSEEEEEEEE----EHHHHHHHHHHHHHHTT??-???B??S??EEEEEEEEEETT----T-??E---EEEEEEEEEEEEETTTTEEEEEEEEEEEEEEE?---T---T?SSSS---????EE-EEEEE??S 4IGL|A PF12265.3_CAF1C_H4-bd_seed 93 103 !Q:5,5|9,12|27,27|30,31|33,34|37,37|39,40|42,49|52,52|54,60|70,78|81,87|89,89|101,102 Q:0,4|6,8|13,26|28,29|32,32|35,36|38,38|41,41|50,51|53,53|61,69|79,80|88,88|90,100 HHHHH-HHH----HHHHHHEEEEEEEE?SS??S??EE?S??B?------?TT?S-------EEEEEEEEE???------SS-------S?EEEEEEEEEEE?? 3C9C|A PF12282.3_H_kinase_N_seed 64 203 !Q:0,0|6,7|11,14|45,53|56,66|74,75|79,80|82,83|85,87|90,90|93,107|119,141|143,146|156,161|163,165|168,170|176,177|180,180|182,183|188,191 Q:1,5|8,10|15,44|54,55|67,73|76,78|81,81|84,84|88,89|91,92|108,118|142,142|147,155|162,162|166,167|171,175|178,179|181,181|184,187|192,202 ?HHHHH--HHH????HHHHHHHHHHHHHTHHHHHHHTSEEEEEEE--------?TT??---------EEEEEEE??SSS??S??S??-TT?EE--------------?GGGSHHHHHHT?????????????????-?????E----EEEEEEEET------T---EE---EEEEE--EE-E??GGGS????HHHHHHHHHHH 2YKH|A PF12289.3_Rotavirus_VP1_seed 2 52 !Q:35,44|46,46 Q:0,34|45,45|47,51 HHHHHHHHHTTGGGSHHHHHHHHHHHHHHHHHHHH?????????-B?HHHHH 4F5X|W PF12296.3_HsbA_seed 71 147 !Q:0,2|12,12|27,33|36,43|67,74|83,83|87,89|112,118|121,121|147,147 Q:3,11|13,26|34,35|44,66|75,82|84,86|90,111|119,120|122,146 ???HHHHHHHHH-HHHHHHHHHHHHHH??-----SS?------?HHHHHHHHHHHHHHHHHHHHTTT-?--????HHHHHHHH?HHH---HHHHHHHHHHHHHHHTHHHHHH-------TT?HHHHHHHHHHHHHHHHHHHHHHHHH- 3L1N|A PF12306.3_PixA_seed 33 228 !Q:0,2|11,11|15,18|22,28|30,30|33,36|40,42|45,49|53,59|65,68|71,77|79,84|87,87|95,95|98,98|110,110|127,134|136,143|149,179|188,188|190,190|193,193|206,207|227,227 Q:3,10|12,14|19,21|29,29|31,32|37,39|43,44|50,52|60,64|69,70|78,78|85,86|88,94|96,97|99,109|111,126|135,135|144,148|180,187|189,189|191,192|194,205|208,226 ???EEEEEEEE?HHH----HHH-------H?SS????TTS--?EE?-?--GGG-------EEEEE???-TT------?B----??TT?TTEEEEE?TT?EEEEEEEETTT-TSSSEEEEEEEEEEEE----?-??B?-----??EEEEE??????????????--------?????????EEEEEEEB?S?EE-EEEEEEEEEEEE--ETTEEEEEEEEEEEEEEEE? 4LZK|A PF12320.3_SbcD_C_seed 203 165 !Q:0,5|11,13|16,17|22,24|32,38|40,41|43,54|56,79|88,88|90,90|95,96|103,104|108,116|122,124|126,126|134,135|137,137|148,148 Q:6,10|14,15|18,21|25,31|39,39|42,42|55,55|80,87|89,89|91,94|97,102|105,107|117,121|125,125|127,133|136,136|138,147|149,164 ???--?EEEEE--?SB??HHHH---HHHHHHH-------T--T?-----------S------------------------SEEEEEES-B?SSHH--HHHHHH-?TTE---------EEEEE???H-HHHHHHH??H-HHHHHHHHTT-STTHHHHHHHHHHTTT 3THO|B PF12324.3_HTH_15_seed 6 81 !Q:0,4|16,20|37,37|39,39|49,53|64,64|67,67|70,70|74,74|78,78 Q:5,15|21,36|38,38|40,48|54,63|65,66|68,69|71,73|75,77|79,80 ??--?HHHHHHHHHHH?????HHHHHHHHHHHHTTSS?B?HHHHHHHHT---??HHHHHHHHHT?TT?EE?TTS?EEE-SS 3F2H|A PF12327.3_FtsZ_C_seed 26 104 !Q:12,14|20,22|31,31|36,36|38,39|43,43|53,53|56,57|73,74|86,86|89,90|102,103 Q:0,11|15,19|23,30|32,35|37,37|40,42|44,52|54,55|58,72|75,85|87,88|91,101 EEEEEEEEEEES---TTHHH---HHHHHHHT?GGGT-T??GGG?SEEEEEEEE?TT??HHHHHHHHHHHHHHS?-TTSEEEEEEEE?TT??SEEEEEEEEES?? 1W5E|A PF12328.3_Rpp20_seed 44 287 !Q:7,8|11,12|30,89|92,106|129,131|136,143|157,274 Q:0,6|9,10|13,29|90,91|107,128|132,135|144,156|275,286 HHTTEEE??SS??HHHHHHHHHHHHHHHHH------------------------------------------------------------HT?--------------SEEEEEEEGGGHHHHHHHHHHH---HHTT-----???EEEEEEEEEEEEE??-----????????????------------------------------------------------------------------------------------------?????????EEEEEEEEEEEE 3IAB|B PF12330.3_DUF3635_seed 6 114 !Q:5,6|8,16|33,35|39,40|59,61|64,68|80,90|110,110 Q:0,4|7,7|17,32|36,38|41,58|62,63|69,79|91,109|111,113 SGGGS??S---------SHHHHHHHHHHHHHTT--?TTS??THHHHHHHHHHHHHHHHS???SS??--?SHHHHHHHHHH-----------HHHHHHGGGSSSHHHHHHH?GGG 3FMD|A PF12344.3_UvrB_seed 509 46 !Q:2,2|5,7|33,46 Q:0,1|3,4|8,32 EE?SS-??HHHHHHHHHHHHHHHHHHHHHHHTT?????-???????- 1D9Z|A PF12348.3_CLASP_N_seed 57 276 !Q:12,14|16,16|20,20|39,41|54,55|67,67|91,91|96,96|110,110|130,134|138,138|148,148|150,150|169,183|190,190|192,196|199,204|215,215|232,249|253,253|262,263|267,267 Q:0,11|15,15|17,19|21,38|42,53|56,66|68,90|92,95|97,109|111,129|135,137|139,147|149,149|151,168|184,189|191,191|197,198|205,214|216,231|250,252|254,261|264,266|268,275 HHHHHHHHHHHH---T?TTS?HHHHHHHHHHHHHHHHTT---GGGSTTHHHHHH--TTHHHHHHHHT?SSHHHHHHHHHHHHHHHHHHGGG-GHHH-HHHHHHHHHTTTT?SSHHHHHHHHHHHHHHHHH??--?TTH-HHHHHHGGG?S?HHHHHHHHHHHHHHHHHS?--------------GGGTTT?H-----HH------HHHHHHHHHT?SSHHHHHHHHHHHHHH------------------HHH?HHHHHHHH--HHS?HHHHHHHH 2QK2|A PF12352.3_V-SNARE_C_seed 20 66 !Q: Q:0,65 HHHHHHHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT 2NPS|C PF12354.3_Internalin_N_seed 32 59 !Q:0,37|40,40|48,48 Q:38,39|41,47|49,58 ----------------------------??????-???SS?EEHHHHS?SHHHHHHHHH 2WQX|A PF12369.3_GnHR_trans_seed 14 84 !Q:0,8|14,71|73,76|78,78|83,83 Q:9,13|72,72|77,77|79,82 ?-?-?????TTTTT????????????????----??????????????????????------?--?-????-S????S?EEES? 4AY9|X PF12391.3_PCDO_beta_N_seed 79 41 !Q:1,4|8,8|10,11|13,14|25,25|28,29|32,39 Q:0,0|5,7|9,9|12,12|15,24|26,27|30,31|40,40 E????TTT-S??S??TTSGGGTTTS?SS??EE?----???H 3T67|M PF12401.3_DUF3662_seed 76 127 !Q:0,7|10,11|23,24|26,26|42,42|44,46|49,50|52,55|70,70|72,76|97,97|99,99|101,101|103,104|111,112|117,117|120,121 Q:8,9|12,22|25,25|27,41|43,43|47,48|51,51|56,69|71,71|77,96|98,98|100,100|102,102|105,110|113,116|118,119|122,126 ????????SS??STHHHHHHTTS--S?THHHHHHHHHHHHHT?B???TT??B-???EEEEEEEHHHHHHH?S---?-SHHHHHHHHHHHHHHHHHHT?B?S-S??EEEEEE--ETTS?TT-?EEEEE 2LC0|A PF12408.3_DUF3666_seed 37 49 !Q:4,6|15,15|24,24|36,38 Q:0,3|7,14|16,23|25,35|39,48 HHHS?-?HHHHHHHS?HHHHHHHT?SHHHHHHHHHH???HHHHHHHHHH 3C5Y|A PF12424.3_ATP_Ca_trans_C_seed 19 69 !Q:23,68 Q:0,22 THHHHHHHHHHHHHHHHHHHHHH??-------------------------------------------- 2KNE|B PF12436.3_USP7_ICP0_bdg_seed 52 369 !Q:9,10|13,22|24,24|28,38|50,51|56,57|59,62|71,72|77,95|99,105|109,110|138,138|143,144|155,160|163,164|174,178|184,196|205,207|211,212|222,223|226,248|255,255|276,278|283,297|306,307|322,323|331,334|337,340|342,342|344,346|349,352|355,359|361,361|366,367 Q:0,8|11,12|23,23|25,27|39,49|52,55|58,58|63,70|73,76|96,98|106,108|111,137|139,142|145,154|161,162|165,173|179,183|197,204|208,210|213,221|224,225|249,254|256,275|279,282|298,305|308,321|324,330|335,336|341,341|343,343|347,348|353,354|360,360|362,365|368,368 GEEEEEEEE-?TT----------S?EEE-------????HHHHTTSBHHH--HHTS-?S----SEEEEEEE??HHHH-------------------TTT???????TTT--EEEEEEEEEETTTTEEEEEEEEEEETT?BGGG--THHHHHHHHT?----?TT??EEEEEEEET-----TEEEE?----------??SSSBHHHH---STT??TTEEEEEEE??GG-----------------------GGGSSS?SHHHHHHHHHHEEEEEEEET---TSTT?-?-----------?EEEEEETT??HHHHHHHHHHHHTS-?GGGEEEE??-?TT----S?S??-SB??--TT---??S?HHHH--S 2KVR|A PF12437.3_GSIII_N_seed 106 184 !Q:1,1|11,12|21,21|35,40|60,61|65,69|71,85|88,88|91,91|93,93|96,96|98,101|103,103|107,109|113,139|141,141|145,146|151,157|162,163|165,174 Q:0,0|2,10|13,20|22,34|41,59|62,64|70,70|86,87|89,90|92,92|94,95|97,97|102,102|104,106|110,112|140,140|142,144|147,150|158,161|164,164|175,183 S?HHHHTTTTB??HHHHHHHS?HHHHHHHHHHHTT????-?HHHHHHHHHHHHHHHGGGT??EEE-????B?----?--???????EE?EE-E?TT-S----S-EEE???GGG???????????????????????????B?SSS??EEET-------TEEE??B??????????BSHHHHHHH 3O6X|A PF12464.3_Mac_seed 351 116 !Q:7,18|20,20|22,22|24,34|36,38|40,40|56,56|58,66|69,74|77,90|93,100|113,114 Q:0,6|19,19|21,21|23,23|35,35|39,39|41,55|57,57|67,68|75,76|91,92|101,112|115,115 HHHHHHT??----------B?T-T----------?H---H-HHHHHHHHHHHHHHH-H---------HS---?--TT------------?-HH--------HHHHHHHHHSSB??S 3ECT|A PF12465.3_Pr_beta_C_seed 63 40 !Q:0,6|9,13|16,16|18,18|27,39 Q:7,8|14,15|17,17|19,26 ???????SS?????TT?S?EEEEEEEE????????-???? 3TDD|H PF12468.3_TTSSLRR_seed 25 52 !Q:0,23|39,39|43,45 Q:24,38|40,42|46,51 ????????????------??????HHHHHHHHHHHHHTS?TTS???HHHHHH 1JL5|A PF12469.3_DUF3692_seed 86 245 !Q:11,11|16,16|41,42|47,58|62,65|70,78|81,81|83,85|93,96|101,142|146,170|182,197|205,226|237,238|245,245 Q:0,10|12,15|17,40|43,46|59,61|66,69|79,80|82,82|86,92|97,100|143,145|171,181|198,204|227,236|239,244 EEEEEEEEESS?TTTT?SSHHHHHHHHHHHHHHHHHHHHHH--HHHT?-----------GGG----EEES------?-?TT?H---HHHHHTT????GGGG------------------------------------------GSB??-?---------------------SEEEEEEETTT----------------HHHHHHH----------------------HHHHHHHHHH--HHHHHH- 3UR3|C PF12481.3_DUF3700_seed 33 315 !Q:5,6|8,8|11,12|17,19|24,24|29,47|52,52|58,68|72,72|82,84|86,93|97,100|105,105|109,109|111,120|126,134|149,150|152,153|162,166|173,176|182,183|193,193|204,204|207,208|210,211|216,216|219,220|234,234|237,239|241,242|244,244|253,253|258,261|268,279|281,286|292,292|297,308|311,311 Q:0,4|7,7|9,10|13,16|20,23|25,28|48,51|53,57|69,71|73,81|85,85|94,96|101,104|106,108|110,110|121,125|135,148|151,151|154,161|167,172|177,181|184,192|194,203|205,206|209,209|212,215|217,218|221,233|235,236|240,240|243,243|245,252|254,257|262,267|280,280|287,291|293,296|309,310|312,314 EEEES??S?HH--HHHH---HHHH-HHHT-------------------TGGG?BTEEE-----------EEE?SSEEEEEEE???S?-------TTT--??SSEE?TTS?E----------EEEEE---------EEETTHHHHHHHHT??S??TTHHHHHH-----HHHHTT----TTGGG??EEEEEEEEE-TTTTEEEEEE?TT??S??EEEE?TT??EEEESSGGGTTTT?EE---E??T-TEEEETTT?SEEE????HHHHHH------------H------HHHHH-HHHT??----------SS?EEE 1CT9|A PF12513.3_SUV3_C_seed 83 50 !Q:20,21|26,27 Q:0,19|22,25|28,49 HHHHHHHHHHHHHHHHHHHH?-TTTS??HHHHHHHHHHHHHHHHHHHHTH 3RC8|A PF12515.3_CaATP_NAI_seed 28 63 !Q:0,26|39,41 Q:27,38|42,62 --------------------------?HHHHHHHHHHHH---HHHHHHHHHHHHHHHHHHHHH 4AQR|D PF12524.3_GlyL_C_seed 10 80 !Q:0,0|2,7|10,11|14,14|18,23|25,58|61,79 Q:1,1|8,9|12,13|15,17|24,24|59,60 ?S??????SS??SS?TTS??????S??????????????????????????????????EE??????????????????? 3M1C|B PF12535.3_Nudix_N_seed 85 58 !Q:0,1|21,23|47,48 Q:2,20|24,46|49,57 ??HHHHHHHHHHHHHHHHHHH???HHHHHHHHHHHHHHHHHHHHHTT??HHHHHHHHS 3Q1P|A PF12538.3_FtsK_SpoIIIE_N_seed 18 125 !Q:14,15|17,19|21,22|28,28|35,35|38,44|50,50|52,59|62,62|70,70|78,78|98,99|102,102|113,114|119,119|122,122 Q:0,13|16,16|20,20|23,27|29,34|36,37|45,49|51,51|60,61|63,69|71,77|79,97|100,101|103,112|115,118|120,121|123,124 EEEEEETTEEEEEE??T---T??EEEES?TTSSEE?TT?---???EEEEE?T--------TS?EEETTEE?SSEEEEE?SSSEEEEEEEEGGGEEEEE??SS?SEEEEESSTT--SSEE?TT?SS 1WV3|A PF12539.3_Csm1_seed 29 146 !Q:9,11|24,29|37,51|59,89|97,104|107,108|111,122|132,132|138,138|146,146 Q:0,8|12,23|30,36|52,58|90,96|105,106|109,110|123,131|133,137|139,145 HHHHHHHHH---HHHSEEEEEEEE?--???EEEEEEE????--?????????EEEEEEE?????------------??-----------?EEEEEEE?-------TT??HH------------HHHHHHTTS?GGGGS?EEEEGGG- 3N4R|A PF12544.3_LAM_C_seed 14 135 !Q:8,8|12,13|28,32|45,45|48,49|55,56|59,68|74,79|83,87|96,97|99,100|104,104|108,108|112,134 Q:0,7|9,11|14,27|33,44|46,47|50,54|57,58|69,73|80,82|88,95|98,98|101,103|105,107|109,111 HHTTBTTB?GGG??EEEEEETTTTEEEE?????EEEEETTEEEEE?TT??EEEEE??TT???--??--?STTTT------TSS?????HHHHHHTT--S-?SEE?BTT?GGG??-----------------???? 2A5H|A PF12563.3_Hemolysin_N_seed 7 206 !Q:0,45|56,69|81,82|88,88|91,92|98,98|111,111|113,114|135,178|183,183|195,196|205,205 Q:46,55|70,80|83,87|89,90|93,97|99,110|112,112|115,134|179,182|184,194|197,204 -------???--------------??????????????????????EEEEEGGGGG??????------??HHHHHHHHTTS??EEEEE?TT??SHHHH-HHHHHHHHHHHS?B??SSEEEEEEETTEEEEEEESS???---------????????????????????????---?????TTTS?EEEEEEEEEEE??TTTTEEES? 3O44|A PF12568.3_DUF3749_seed 21 157 !Q:0,1|6,6|8,11|13,14|25,34|38,53|79,80|90,90|93,93|104,107|115,117|119,120|125,126|129,129|131,132|146,148|151,151 Q:2,5|7,7|12,12|15,24|35,37|54,78|81,89|91,92|94,103|108,114|118,118|121,124|127,128|130,130|133,145|149,150|152,156 ??EEEE?S----S??HHHHHHHHHH?---------TTS??????--?------?SSEEEEEEEETTEEEEEEEEEEETT--EEEEEEEEE?TT?SSSSHHHHHH----HHHHHHS--?S??EEEE??TT?S--THHHHHHHHHHHT?--EE?SSSEE 2EUI|A PF12569.3_NARP1_seed 32 618 !Q:27,28|35,37|54,54|69,69|72,72|87,113|117,118|120,120|135,136|139,139|150,168|188,188|201,201|219,221|234,236|240,243|261,264|267,274|277,278|291,292|295,295|311,311|326,326|329,329|345,345|358,359|374,374|390,390|424,424|440,440|461,461|463,464|469,471|482,491|493,493|503,505|527,557|559,559|567,567|569,571|590,590|606,606 Q:0,26|29,34|38,53|55,68|70,71|73,86|114,116|119,119|121,134|137,138|140,149|169,187|189,200|202,218|222,233|237,239|244,260|265,266|275,276|279,290|293,294|296,310|312,325|327,328|330,344|346,357|360,373|375,389|391,423|425,439|441,460|462,462|465,468|472,481|492,492|494,502|506,526|558,558|560,566|568,568|572,589|591,605|607,617 HHHHHHHHHHHHHHHHHTHHHHHHHHH--HHSGGG???HHHHHHHHHHHHHHTT?HHHHHHHHHHHHHH?TT?HHHHHHHHHHTTSS?--------------------------SSS??S?HHHHHHHHHHTTTS?-TT?SHHHHTHHHH??-----------------THHHHHHHHHHHHHHHHHT?TTHHHHHGGGGG-GSHHHHHHHHHHHHHHT---TTTTSSSSTTGG---GSS????SSHHHHHHHHHHHHHHH----HT?-------SH--HHHHHHHHHHHH?-TT?HHHHHHHHHHHHHTT?HHHHHHHHHHHHHH?SS?HHHHHHHHHHHHHTT?HHHHHHHHTTTS??SSSSHHHHHHHHTT?HHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHTTTTHHHHHHHHT?HHHHHHHHHHHHTTT?SHHHHHHHHHHHHHHHHHHH?T--TGGG???HHHHHHHHHT---------?S?HHHHHHHHH---HHHHHHHHHHHHHHHHHHHHH??-------------?????????????---S?SSSTTTT?S--?HHHHHHHHHTTTGGGTTT?THHHHHHHHHHHHTT?HHHHHHHHHHH 4KVO|A PF12573.3_OxoDH_E1alpha_N_seed 28 44 !Q:1,10|12,13|17,19|24,27|30,30|32,36|39,40 Q:0,0|11,11|14,16|20,23|28,29|31,31|37,38|41,43 S??????????S??TTS???GGGS????TT?S?-???TT??GGG 2BP7|A PF12574.3_120_Rick_ant_seed 7 340 !Q:7,7|9,9|27,27|30,30|35,38|40,40|53,53|78,149|153,153|156,156|160,162|165,165|167,167|169,169|179,179|183,183|194,194|196,197|202,202|206,206|211,211|217,219|222,223|225,225|227,227|236,236|242,245|249,250|259,261|273,273|286,286|318,323|326,327|330,331|336,339 Q:0,6|8,8|10,26|28,29|31,34|39,39|41,52|54,77|150,152|154,155|157,159|163,164|166,166|168,168|170,178|180,182|184,193|195,195|198,201|203,205|207,210|212,216|220,221|224,224|226,226|228,235|237,241|246,248|251,258|262,272|274,285|287,317|324,325|328,329|332,335 HHHHHHT?S?HHHHHHHHHHHHHHHHH?TT?HHHH----H?GGGHHHHHHHHT?HHHHHHHHHHHHHHHHHHHHHSBT------------------------------------------------------------------------TTT?TT?BEE???EE?S-S?TTEEEEEEE?TTS?EEEEEEEEEE?S??EEEE?TTS?EEEE?BEEEE???SB??S-S?SEEEEEEE?EETBS????TTT??EEEEEEEE?--TTSSEEEEEEE?SSSEEEESSSTT?EEEEEETTEEEEEEEEHHHHHHHHHHHHHTT??????EE--EE??EESS??-- 4LQ8|A PF12580.3_TPPII_seed 24 258 !Q:4,4|6,6|9,9|26,27|29,30|36,37|45,45|50,50|61,85|88,88|90,90|97,97|103,103|107,107|111,113|118,118|122,122|128,128|131,131|133,161|163,164|168,168|182,182|192,193|201,201|203,203|209,210|221,223|225,228|232,232|234,234|242,246|255,256 Q:0,3|5,5|7,8|10,25|28,28|31,35|38,44|46,49|51,60|86,87|89,89|91,96|98,102|104,106|108,110|114,117|119,121|123,127|129,130|132,132|162,162|165,167|169,181|183,191|194,200|202,202|204,208|211,220|224,224|229,231|233,233|235,241|247,254|257,257 EEEE-E-SS?EEEEEEEEEEEEEEEE??S?-EEEEE??SSSSEET-TTEE?EEEEEEEEEE-------------------------ES-S?EEEEEE?TTTTT?SSS?SSS???EEEE?TTS?EEEEE?SS?T-----------------------------T??EEE?SEEEEEEEEEEES?HHHHGGGTT??EEEEEEE-E-EEEEE??BSSHHHHHTT--?S????EEE?S-SEEEEEE-????HHHHHTTT??T 3LXU|X PF12583.3_TPPII_N_seed 7 145 !Q:0,74|94,94|109,109|112,112|129,133|143,145 Q:75,93|95,108|110,111|113,128|134,142 ??????????????????-?????????????????????--???????????????????-?????????????HHHHHHHHHHHHHHHHTTS?HHHHHHHHHHHHHH?TT?THHHHHHHHHHHHHSS?-???HHHHHHTTS??- 3LXU|X PF12592.3_DUF3763_seed 26 64 !Q:0,1|21,27|33,35|39,39|61,63 Q:2,20|28,32|36,38|40,60 ??HHHHHHHHHHHHHHHHHHH-------HHHTT???TTS?HHHHHHHHHHHHHHHHHHHHH??? 3NBX|X PF12602.3_FinO_N_seed 3 102 !Q:0,47|55,63|75,91 Q:48,54|64,74|92,101 ----------------------------------------------??HHHHHHH---------HHHHHHHHHHH-----------------HHHHHHHHHH 1DVO|A PF12604.3_gp37_C_seed 9 214 !Q:0,19|24,28|32,32|35,36|42,42|54,54|56,56|60,62|77,77|80,80|95,95|99,99|102,102|107,109|122,122|124,127|135,142|145,145|149,149|152,160|162,172|174,174|180,180|184,184|190,194|196,200|207,208 Q:20,23|29,31|33,34|37,41|43,53|55,55|57,59|63,76|78,79|81,94|96,98|100,101|103,106|110,121|123,123|128,134|143,144|146,148|150,151|161,161|173,173|175,179|181,183|185,189|195,195|201,206|209,213 ???---???--------???EEEE-----EEE?TT??EEEEE-EETTEEEEEEE-E?STT???EEEEETTTTEEEEE?SS?EEESSEEEETTEEE?TTS?EE?GGGT---TSBHHHHHHHHB?B????EEEEEES??-----?TT?EEE?SS-------??T-----------T?EEEEE?GGG?EEEEE?---?S-----SEEEEE??TTSEE 4A0U|A PF12623.2_Hen1_L_seed 27 268 !Q:0,0|7,12|16,16|26,27|30,31|49,49|52,52|62,62|65,86|92,92|98,99|117,118|128,128|140,141|143,144|159,159|161,161|170,170|173,173|177,177|189,189|192,192|208,208|214,222|234,234|241,267 Q:1,6|13,15|17,25|28,29|32,48|50,51|53,61|63,64|87,91|93,97|100,116|119,127|129,139|142,142|145,158|160,160|162,169|171,172|174,176|178,188|190,191|193,207|209,213|223,233|235,240 ?EEEEEE?-----SSS-TTHHHHHHT??TT??EEEEETTEEEEEEEEEE?SS?EEEEEEEEE?SS???---??????---???--??GGGTS?SGGGS??HHHHHHHHHHSTGGGGT??SSSTTGGGS?EEEEEEEEEEE?-T--THHHHHHHHHGGGT?E-EEEEEEES?TT?GGG?EEEEEEEEEEE-EE?HHHHHHHHHHHHHHH?TTGGG?????????STTTSTTTTTT?TTHHHH?????-------------------??? 4DRF|B PF12626.2_PolyA_pol_arg_C_seed 70 145 !Q:4,7|28,30|49,50|52,53|63,63|82,87|103,104|107,108|118,145 Q:0,3|8,27|31,48|51,51|54,62|64,81|88,102|105,106|109,117 HHTT--??HHHHHHHHHHHHHHHHHHHS???HHHHHHHHHHHHHHTTSS--S??TTTHHHHHH?TTHHHHHHHHHHHHHHTT?-----HHHHHHHHHHHHHHH??HH--HHHHHHHHH?--------------------------- 3AQK|A PF12627.2_PolyA_pol_RNAbd_seed 312 70 !Q:1,1|4,4|17,18|24,24|40,40|54,54|56,56|60,62|69,69 Q:0,0|2,3|5,16|19,23|25,39|41,53|55,55|57,59|63,68 S?EE?HHHHTHHHHHGG--GGGGS?HHHHHHHHHHHHTTT-THHHHHHHHHTTT?H-HHH?--HHHHTT? 3AQK|A PF12628.2_Inhibitor_I71_seed 4 175 !Q:0,12|18,21|24,24|34,34|37,37|51,51|62,66|71,71|74,78|81,81|87,89|92,129|132,132|143,143|156,156|159,159|164,164|174,174 Q:13,17|22,23|25,33|35,36|38,50|52,61|67,70|72,73|79,80|82,86|90,91|130,131|133,142|144,155|157,158|160,163|165,173 ------???????EEEEE????SS?EEEEEEEEE?TT?EEEEEEEEETTSS?EEEEEEEESS?????GGGS?SS?????EE?SSEEE???EE??????????????????????????-???????--??BT?EEEEEEEEEE?SSEEEEEEEEEE?TT?TTSS?EEEEEEEEE? 3PNR|B PF12629.2_Pox_polyA_pol_C_seed 13 270 !Q:19,19|36,38|42,45|48,52|55,55|57,58|62,65|76,76|80,82|93,93|97,116|126,132|135,135|139,144|152,152|155,155|157,175|179,180|182,187|194,194|196,196|209,211|219,221|224,224|236,245|248,257|269,269 Q:0,18|20,35|39,41|46,47|53,54|56,56|59,61|66,75|77,79|83,92|94,96|117,125|133,134|136,138|145,151|153,154|156,156|176,178|181,181|188,193|195,195|197,208|212,218|222,223|225,235|246,247|258,268 HHHHHHHTTSHHHHHHHHH?THHHHHHHHHHHHHHH---HHH????SS?---?SS?S??EEE----ETTTTEEEEE?TTT---SSSSEEEEES?HHH--------------------HHHHHHHTT--????-EE?GGG------TSSEEEE?SS?E-------------------EEE??S----??EESSTT?B?HHHHHHHHHHHH---HHHHHTT???SH-HHHHHHHTTSS??---?????EE??????????EEEETTTTEEE? 2GAF|D PF12630.2_Pox_polyA_pol_N_seed 13 131 !Q:0,11|24,26|47,47|54,56|66,67|69,72|74,74|92,95|118,125|129,130 Q:12,23|27,46|48,53|57,65|68,68|73,73|75,91|96,117|126,128 ????????????HHHHHHHHHHTS???HHHHHHHGGGHHHHHHHHTS?TTHHHH---HHHHHHHHH??S??--S?TTHHHHHHHHHTTHHHH??-?HHHHHHHHHHHHHHHHHHHHHT--------TTT?? 2GAF|D PF12631.2_GTPase_Cys_C_seed 534 125 !Q:3,4|7,10|19,19|27,27|30,40|46,52|55,76|80,82|99,100|102,102|104,106|108,111|113,113|124,124 Q:0,2|5,6|11,18|20,26|28,29|41,45|53,54|77,79|83,98|101,101|103,103|107,107|112,112|114,123 SSS??SS????HHHHHHHH-HHHHHHH-HH-----------HHHTT-------TT-----??---------------GGG---THHHHHHHHHHHHHHH--T-S---S?-?-H-HHHHHHHHTS? 3GEI|A PF12639.2_Colicin-DNase_seed 57 167 !Q:0,0|5,5|8,8|11,12|14,16|19,22|28,29|34,34|37,37|47,51|53,53|70,84|87,87|95,95|103,103|107,109|111,112|116,116|121,125|127,127|134,134|139,140|151,151|158,162 Q:1,4|6,7|9,10|13,13|17,18|23,27|30,33|35,36|38,46|52,52|54,69|85,86|88,94|96,102|104,106|110,110|113,115|117,120|126,126|128,133|135,138|141,150|152,157|163,166 ?GGGS?EE?BS??B???TT----GGGGG--GSTT?EE?BHHHHHHHT-----T?EESSHHHHHHHHHHHH---------------HT?HHHHTTS?HHHHHHH-HTT???B??GGG?BTTB----?B?EEEESS?GGGT??TTBTTTEEEE?HHHHHH-----HHTT 2GZJ|B PF12642.2_TpcC_seed 47 321 !Q:11,15|17,17|20,20|30,30|34,34|42,43|45,55|70,79|98,98|101,106|109,110|117,133|144,147|150,151|155,155|157,158|161,166|168,176|180,182|187,192|210,210|219,219|222,234|236,237|240,247|267,279|287,291|306,306|309,312|319,320 Q:0,10|16,16|18,19|21,29|31,33|35,41|44,44|56,69|80,97|99,100|107,108|111,116|134,143|148,149|152,154|156,156|159,160|167,167|177,179|183,186|193,209|211,218|220,221|235,235|238,239|248,266|280,286|292,305|307,308|313,318 HHHHHHHHHHT?----B?TT?HHHHHHHHT-TTS?HHHHHHH??S---------??EEEEEEEEEEEEEE----------ETTEEEEEEEEEEEEEEE?TT??????TT??EEEEEE-----------------EEEEEEEEEE---?TT??EEE?S??EE??-???B?????????SEE???HHHH------HHHHHHHHHHHHHHHHS?HHHHHTTB?TT?------??????S??EE--------EEEEEEEEEEEETTEEEEE-------------EEEEEEE-----TTEEEEEEEEEEEE-EE----TTEEEE?? 3UB1|A PF12658.2_Ten1_seed 27 244 !Q:0,10|13,28|30,30|37,37|40,40|47,63|70,71|74,76|83,84|89,106|111,112|114,115|118,142|145,145|159,219|228,228|231,232|237,238 Q:11,12|29,29|31,36|38,39|41,46|64,69|72,73|77,82|85,88|107,110|113,113|116,117|143,144|146,158|220,227|229,230|233,236|239,243 ??-------??EE?--------------?G-GGGGGS?TT?EEEEEE-----------------EEEEEE--TT---EEEEEE--TTEE------------------EEEE??S??TT-?--------------------???TT?EEEEEEEEEETTE-------------------------------------------------------------EEEEEEEE?TT??HHHH--HHHHH 3KF6|B PF12659.2_Stn1_C_seed 10 134 !Q:0,2|36,36|58,58|71,72|76,76|79,80|99,99|111,121|130,130 Q:3,35|37,57|59,70|73,75|77,78|81,98|100,110|122,129|131,133 ???HHHHHHHHHHHHHHHHHHTTSSEEEETTTTEEE?HHHHHHHHHHHHHHHHHHHTT?SEEEEEHHHHHH--HHT?TT??HHHHHHHHHHHHHHHHHH?TTTEEEEEEEE???????????EEEEEEEE?TTT 3K10|A PF12660.2_zf-TFIIIC_seed 16 129 !Q:10,12|14,17|23,35|41,41|45,47|52,52|56,57|59,61|63,63|65,65|68,68|72,74|78,78|82,82|86,88|90,106|118,118|120,121|124,125|127,127 Q:0,9|13,13|18,22|36,40|42,44|48,51|53,55|58,58|62,62|64,64|66,67|69,71|75,77|79,81|83,85|89,89|107,117|119,119|122,123|126,126|128,128 EETTEEEEEE---S----GGGTT?------------SSEEE?TTS?--EEEB?SSS??B???S?E-EE?TTT?-?EEE?GGG?SSS???H-----------------HHHHHHHHTSB?T--TT??B?E 2J04|A PF12661.2_hEGF_seed 521 13 !Q:0,12 Q: ????????????? 1CCF|A PF12662.2_cEGF_seed 733 60 !Q:1,1|4,5|7,12|15,27|29,37|39,39|42,42|45,53|55,59 Q:0,0|2,3|6,6|13,14|28,28|38,38|40,41|43,44|54,54 S?EE--E---??-TT??-----------E---------E-TT-TE---------E????? 3GCW|E PF12667.2_NigD_seed 55 290 !Q:9,11|14,19|27,28|39,43|46,52|55,55|61,62|64,67|75,80|100,100|102,106|108,108|110,110|113,114|117,117|119,119|122,126|128,128|134,139|142,144|146,147|157,175|184,194|198,199|215,219|222,235|237,247|253,254|258,259|262,270|281,281|288,288 Q:0,8|12,13|20,26|29,38|44,45|53,54|56,60|63,63|68,74|81,99|101,101|107,107|109,109|111,112|115,116|118,118|120,121|127,127|129,133|140,141|145,145|148,156|176,183|195,197|200,214|220,221|236,236|248,252|255,257|260,261|271,280|282,287|289,289 EEEEEEEET---TE------EEEEETT--TEEEEEEEES?----TT---????TT?EEEEE--E----EEEEEEE------TTEEEEEEEEEEEEEEEEE?E-----E-E?TT--TT-T-SS?????B?TTEEE------EE---E--TTEEEEEES????---------???--?EEEEEEEE?----------STT??SSTTTSEEEEEEEEE-----ES?--??-??????--E-----------EEEEE?-TTS??TT--?-----?EEEEEEEETT-TEEEEE-E 3QWN|A PF12678.2_zf-rbx1_seed 110 170 !Q:5,9|11,13|21,21|23,27|31,50|52,66|70,70|72,72|74,74|77,80|82,83|90,95|97,113|115,116|119,121|124,124|127,127|135,144|149,150|152,153|155,155|157,163|165,165|169,169 Q:0,4|10,10|14,20|22,22|28,30|51,51|67,69|71,71|73,73|75,76|81,81|84,89|96,96|114,114|117,118|122,123|125,126|128,134|145,148|151,151|154,154|156,156|164,164|166,168 SEEEE-----E---EEEEEEE-E-----ESS?-------------------S?----------?--?SSS?S?T-TS??--T--THHHHT------T-?-----?????---??E--EE---ET-TS?EEEHHHH----------HHHH--T--T?S-------B?SSS? 3DPL|R PF12680.2_SnoaL_2_seed 623 314 !Q:1,1|4,6|8,8|10,10|12,14|17,17|19,19|21,26|28,35|37,40|42,45|47,47|49,52|54,61|64,67|69,72|74,77|80,80|82,82|84,86|88,91|93,101|103,108|112,123|125,125|129,133|138,145|153,167|177,177|180,180|183,192|196,197|199,202|204,212|217,218|220,224|232,240|242,243|245,251|255,260|265,281|286,287|289,290|294,296|298,300|302,302|304,306|308,309 Q:0,0|2,3|7,7|9,9|11,11|15,16|18,18|20,20|27,27|36,36|41,41|46,46|48,48|53,53|62,63|68,68|73,73|78,79|81,81|83,83|87,87|92,92|102,102|109,111|124,124|126,128|134,137|146,152|168,176|178,179|181,182|193,195|198,198|203,203|213,216|219,219|225,231|241,241|244,244|252,254|261,264|282,285|288,288|291,293|297,297|301,301|303,303|307,307|310,313 H-HH---H-H-H---HT-T-T------T?---?---H----H----H-H----H--------HH----E----E----EE-E-E---E----T---------T?----?TTS-----------?S-SHH-----HHHH--------HHHHTHH---------------HHEEEEEEE-EE-EE----------EEE--T----T---------EEEE--E-----EEEEEEE--------?S-?B-------TTB?????-EEEE-----------------EEEE--E--EEE---E---T-T---E--EEEE 2F98|A PF12681.2_Glyoxalase_2_seed 429 441 !Q:3,4|6,10|14,15|24,24|26,32|34,35|37,39|43,61|64,66|68,71|73,74|76,81|84,86|88,88|91,96|98,113|115,116|119,162|164,167|169,170|173,173|176,180|182,187|189,191|195,222|224,224|226,228|230,234|236,250|253,260|262,263|266,270|272,273|275,275|277,284|286,291|293,294|297,298|300,302|305,307|313,329|331,353|355,356|358,361|363,365|367,368|370,376|378,410|412,414|416,418|422,423|425,426|428,428|430,432|434,435 Q:0,2|5,5|11,13|16,23|25,25|33,33|36,36|40,42|62,63|67,67|72,72|75,75|82,83|87,87|89,90|97,97|114,114|117,118|163,163|168,168|171,172|174,175|181,181|188,188|192,194|223,223|225,225|229,229|235,235|251,252|261,261|264,265|271,271|274,274|276,276|285,285|292,292|295,296|299,299|303,304|308,312|330,330|354,354|357,357|362,362|366,366|369,369|377,377|411,411|415,415|419,421|424,424|427,427|429,429|433,433|436,440 EEE--S--?--HHH--HHHHHHHH-H------?E--E---EEE-------------------EE---T----T--E------EE---E-EE------S----------------S?-TT-------------------------------------------?E----E--EE-EE-----T------T--?TTS------------------------?---G-G---G?----S-----??--------BS--------E--EE-----E--E-E?-------S-?----H--HH--H---HH---HHHHT-----------------T------???--------------S--E----E---E--E-------E-----------???--------------?----E---E---EEE--E--E?T---T??EEEEE 3LM4|A PF12682.2_Flavodoxin_4_seed 5 185 !Q:0,0|6,7|10,30|46,46|51,52|56,58|63,63|66,66|77,77|80,83|86,88|90,90|94,94|103,103|108,109|120,121|124,124|132,132|135,136|146,146|149,149|155,157|160,162|164,173 Q:1,5|8,9|31,45|47,50|53,55|59,62|64,65|67,76|78,79|84,85|89,89|91,93|95,102|104,107|110,119|122,123|125,131|133,134|137,145|147,148|150,154|158,159|163,163|174,184 ?EEEEE??SS---------------------SHHHHHHHHHHHHHT?EEEE??BSS???TGGG?TT?TTSHHHHHHT?TT????BS???S?GGG?SEEEEEEE?BTTB??HHHHHHHHTS??TT?EEEEEEE?SS??SHHHHHHHH-HH?TTSEE???EE?-?S??-------?HHHHHHHHHHT 3ESX|A PF12683.2_DUF3798_seed 16 299 !Q:0,1|9,10|14,14|34,45|53,54|74,74|84,84|87,89|100,100|110,111|113,120|134,135|152,152|154,154|166,166|186,187|194,196|221,222|224,225|246,247|250,252|255,256|267,270|276,276|293,293 Q:2,8|11,13|15,33|46,52|55,73|75,83|85,86|90,99|101,109|112,112|121,133|136,151|153,153|155,165|167,185|188,193|197,220|223,223|226,245|248,249|253,254|257,266|271,275|277,292|294,298 ??EEEEEEE??TTT?HHHHHHHHHHHHHHHHHTT????????????EEEEEEE??TTGGGGHHHHHHHHHGGGG?TTEEEEEEE?SS???HHHHHHHHHH?TTSEEEESS??S-------?HHHHHHHSSEEEE??HHHHHHHHHHHHHHTT?S?EEEEEETTGGG-SHHHHHHHHHHHHHHHHTT??EEEEEE???SSTHHHHHHHHHHHHHHHHHHHHH-?S??EEEESSHHHHHHHHHHHHHH??BB???SS??TTTTHHHHHT????GGGTT?HHHHHHHHHHHHHHTT?TTSBE 3QI7|A PF12684.2_DUF3799_seed 19 289 !Q:1,1|12,12|17,23|35,46|58,58|63,65|72,78|80,80|85,92|98,98|114,114|123,123|125,130|158,159|168,169|172,174|183,187|189,189|207,208|212,215|219,223|231,231|235,236|243,243|245,248|260,260|275,279|281,281 Q:0,0|2,11|13,16|24,34|47,57|59,62|66,71|79,79|81,84|93,97|99,113|115,122|124,124|131,157|160,167|170,171|175,182|188,188|190,206|209,211|216,218|224,230|232,234|237,242|244,244|249,259|261,274|280,280|282,288 H?EEHHHHHHHH?BTTB??----?HHHHHHHHHTS??------????HHHHHHHHHHH-HHHT--?HHHHHH-------H?GGGB?-------TTSSB?HHHHHHHHHHHHHHT?HHHHHHTT-S------EEEEEEEEEETTEEEEEEEEEEETTTE--EEEEEEES-?SS-??EEETTTEE-----E?HHHHTTHHHHHHHHHHH--HHH----HHS-????EEEEEEE?SSS??EEEEEE?H----HHHHHHHHHHH-HHHHHHHHHHTTSS?????S?SHHHHHH 3H4R|A PF12685.2_SpoIIIAH_seed 84 365 !Q:0,226|228,248|273,273|277,277|309,309|311,311|313,313|318,318|322,322|324,325|332,332|334,338|350,350|353,353|356,356 Q:227,227|249,272|274,276|278,308|310,310|312,312|314,317|319,321|323,323|326,331|333,333|339,349|351,352|354,355|357,364 -------------?----------------------------?????--??????????????????????????????????????????????????--------------------------------------------------------------?????????---------------------------------------??????????????????H---------------------HHHHHHHHHHHHHHHHHHHHHHHT?TTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT-T?S?EEEE?SSS-E--EEEEEE?S?--??HHHHHHHHHTS?HH-HH-TTSEEEEE 3UZ0|A PF12688.2_TPR_5_seed 8 125 !Q:0,19|30,32|52,52|67,67|70,73|89,89|105,107|123,123 Q:20,29|33,51|53,66|68,69|74,88|90,104|108,122|124,124 --------------??????HHHHHHHHSS???HHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHH?TT---?HHHHHHHHHHHHHHT?HHHHHHHHHHHHHHH???HHHHHTHHHHHHHTT?T 3K9I|A PF12689.2_Acid_PPase_seed 43 258 !Q:0,2|8,8|17,17|22,41|43,43|47,47|51,60|63,70|74,75|78,80|89,95|100,108|111,112|118,119|121,121|123,125|137,137|139,159|163,166|169,169|175,178|180,182|193,198|201,205|215,215|225,225|228,228|233,235|238,240|242,243 Q:3,7|9,16|18,21|42,42|44,46|48,50|61,62|71,73|76,77|81,88|96,99|109,110|113,117|120,120|122,122|126,136|138,138|160,162|167,168|170,174|179,179|183,192|199,200|206,214|216,224|226,227|229,232|236,237|241,241|244,257 ???SEEEE?SBTTTBSS?TTTT------------------??S?EEE?TTS---------?EE--------ETT??EE???TTHHHHHH-------HHHH---------TT??EEEEE??S?H---HHHHHHHHHTT?G---------------------GGE----EE-EEESS----S--?HHHHHHHHHH------HH??--?GGGEEEEES?HHHHHHHHT-TT?EEEE?--SS---S??HHHHHHHHHHHHHH 1U7O|A PF12690.2_BsuPI_seed 39 101 !Q:0,0|10,10|14,14|23,24|31,42|45,46|55,61|67,67|70,70|76,76|82,91|96,96 Q:1,9|11,13|15,22|25,30|43,44|47,54|62,66|68,69|71,75|77,81|92,95|97,100 ?EEEEEEEEE?SSS?EEEEESSS??EEEEEE-----------?TT??EEEETTTT???????EEEEE?TT?EEEEE-EEESS???-------SEEE-EEEE 3ISY|A PF12692.2_Methyltransf_17_seed 18 163 !Q:0,1|27,29|31,31|36,37|40,40|50,51|54,54|62,65|69,71|79,79|92,92|94,94|101,104|106,106|136,140|143,143|147,149|152,153|157,157|162,162 Q:2,26|30,30|32,35|38,39|41,49|52,53|55,61|66,68|72,78|80,91|93,93|95,100|105,105|107,135|141,142|144,146|150,151|154,156|158,161 ??HHHHHHHHHHHHHHHHHHHHHHTTT??-S?EEEE??TT?HHHHHHHHH??SS?EEEEESS????GGG???GGGEEES?HHHHHHHHHHHH?S?EEEEEE????S?HHHHHHHHHHHHHHHGGGEEEEEEEEESS???-?SS?EEE???TT??TTT?EEEE? 3IHT|A PF12693.2_GspL_C_seed 23 189 !Q:0,88|104,105|110,110|127,128|140,145|155,155|160,164|166,168|171,174|183,184|186,188 Q:89,103|106,109|111,126|129,139|146,154|156,159|165,165|169,170|175,182|185,185 ------------------------------------------------?----------------------------------??????HHHHHHGGGHHHHHH--TSTT?EEEEEEEETTTTEEEE--EEEESSSHHHH------HHHHHHHTT-EEEE-----E???EE????EEEEEEEE--E--? 2W7V|A PF12694.2_MoCo_carrier_seed 28 157 !Q:2,5|21,22|25,25|28,28|32,33|38,39|43,45|48,48|51,52|72,72|76,77|92,98|108,108|113,114|127,128|134,136|140,140|156,156 Q:0,1|6,20|23,24|26,27|29,31|34,37|40,42|46,47|49,50|53,71|73,75|78,91|99,107|109,112|115,126|129,133|137,139|141,155 EE????TTHHHHHHHHHHHTT??EE?EE?GGG??TTSS??TTS-??EE?SS??HHHHHHHHHHTSSEEEEEE-SSS??HHHHHHHHHHHHTT??-----EEEEETTTS?HHHH--HHHHHHHHHHTT??EEEEE???TTT?TTHHHHHHHHHHHHH? 3IMK|A PF12695.2_Abhydrolase_5_seed 308 739 !Q:5,15|17,27|29,38|40,41|43,47|49,52|54,60|62,64|67,67|69,71|73,79|82,82|86,86|88,89|95,128|130,132|134,136|138,143|145,150|152,162|167,188|199,257|261,261|267,274|280,282|285,287|295,295|299,299|303,305|310,392|394,400|402,406|408,409|411,413|416,419|422,422|424,475|477,507|509,567|573,575|579,582|586,593|595,596|598,598|601,602|605,660|666,667|669,671|675,675|677,681|683,683|685,726|730,730|732,732|734,736 Q:0,4|16,16|28,28|39,39|42,42|48,48|53,53|61,61|65,66|68,68|72,72|80,81|83,85|87,87|90,94|129,129|133,133|137,137|144,144|151,151|163,166|189,198|258,260|262,266|275,279|283,284|288,294|296,298|300,302|306,309|393,393|401,401|407,407|410,410|414,415|420,421|423,423|476,476|508,508|568,572|576,578|583,585|594,594|597,597|599,600|603,604|661,665|668,668|672,674|676,676|682,682|684,684|727,729|731,731|733,733|737,738 EEEEE-----??----T-----------T?-----?---G--G-----G----G-------H---HH-H---H-------HH-HHT-T-?EEEEE??--------------------------------S?--T---T-?---?H------H-----------HHHH----------------------HHHHHHHHHH-----------------------------------------------------------HTS?HHHHT--------TEEEE---EE---EEEEETH-HHH-HHH---HHHH-----------------------------------------------------------------------------------H---?---T-----T?-S--?EE----EE-S--?--------------------?---------------------------?S--------??--------???--------??S----------------------------------------------------------?EEEEE---ETT---?SSS-------?T--T-TT--HH--------------------------------------------------------HHHHH--S?--TTS?E-----E-E------------------------------------------EEE-T-T?-?TT 1ZI9|A PF12696.2_TraG-D_C_seed 232 172 !Q:0,0|7,7|12,12|14,15|25,25|38,38|45,47|50,52|54,56|60,61|66,66|69,70|72,75|78,78|80,86|89,91|93,96|105,105|108,112|118,118|120,153|162,162|169,170 Q:1,6|8,11|13,13|16,24|26,37|39,44|48,49|53,53|57,59|62,65|67,68|71,71|76,77|79,79|87,88|92,92|97,104|106,107|113,117|119,119|154,161|163,168|171,171 ?EEEEES?GGGS?B?-SSHHHHHHH?TTTTEEEEEEES?HHHHHH---HH?--H---HHH--HHHH-HT??E----EE-E????---TT--?H----HHHHHHHH-HH?----EEEEE-E??????????----------???-------????EEEEEESS?HHHHHT??T 1GKI|A PF12697.2_Abhydrolase_6_seed 785 1424 !Q:1,1|3,3|5,5|7,22|24,34|36,43|45,60|62,62|64,67|70,71|73,84|86,86|88,90|92,94|97,98|100,110|113,117|119,129|131,142|144,152|154,168|171,173|175,191|193,193|195,199|201,203|205,209|211,216|218,281|283,284|286,327|329,332|334,353|355,357|359,359|361,372|375,406|408,408|410,449|451,451|453,460|462,465|467,471|473,477|479,484|486,486|488,521|523,527|529,580|582,584|586,587|589,590|594,594|596,596|598,598|600,606|608,608|610,612|614,614|617,620|622,622|624,646|649,653|655,660|663,674|677,678|681,690|692,693|695,698|702,709|711,712|714,714|723,723|725,832|834,834|837,837|839,843|845,845|849,862|866,880|886,889|891,894|896,900|905,915|917,924|926,932|936,937|939,942|944,962|965,982|986,1016|1028,1048|1051,1051|1054,1055|1058,1058|1063,1133|1137,1142|1144,1147|1150,1150|1152,1154|1157,1183|1185,1190|1192,1197|1200,1201|1203,1207|1209,1213|1217,1218|1220,1249|1251,1251|1253,1269|1272,1272|1274,1274|1277,1300|1304,1306|1308,1311|1313,1314|1316,1318|1320,1324|1326,1327|1329,1347|1349,1351|1353,1355|1357,1362|1364,1365|1367,1367|1369,1373|1375,1380|1383,1386|1388,1390|1392,1392|1394,1396|1398,1400|1402,1406|1408,1410|1412,1412|1414,1416|1418,1420 Q:0,0|2,2|4,4|6,6|23,23|35,35|44,44|61,61|63,63|68,69|72,72|85,85|87,87|91,91|95,96|99,99|111,112|118,118|130,130|143,143|153,153|169,170|174,174|192,192|194,194|200,200|204,204|210,210|217,217|282,282|285,285|328,328|333,333|354,354|358,358|360,360|373,374|407,407|409,409|450,450|452,452|461,461|466,466|472,472|478,478|485,485|487,487|522,522|528,528|581,581|585,585|588,588|591,593|595,595|597,597|599,599|607,607|609,609|613,613|615,616|621,621|623,623|647,648|654,654|661,662|675,676|679,680|691,691|694,694|699,701|710,710|713,713|715,722|724,724|833,833|835,836|838,838|844,844|846,848|863,865|881,885|890,890|895,895|901,904|916,916|925,925|933,935|938,938|943,943|963,964|983,985|1017,1027|1049,1050|1052,1053|1056,1057|1059,1062|1134,1136|1143,1143|1148,1149|1151,1151|1155,1156|1184,1184|1191,1191|1198,1199|1202,1202|1208,1208|1214,1216|1219,1219|1250,1250|1252,1252|1270,1271|1273,1273|1275,1276|1301,1303|1307,1307|1312,1312|1315,1315|1319,1319|1325,1325|1328,1328|1348,1348|1352,1352|1356,1356|1363,1363|1366,1366|1368,1368|1374,1374|1381,1382|1387,1387|1391,1391|1393,1393|1397,1397|1401,1401|1407,1407|1411,1411|1413,1413|1417,1417|1421,1423 E-E-E-E--------?--?----T-----------T----?--?G----------------G-G----GH--H------------H-H---H---HH--H-----------TT-----T-----------E------------E---------E---------------EE---E-----?---?-------T-T-----S---T-----T------S-------?-----------------------------------------------------??-S--S---------------------------?------------?-S----H--------------------H---H-H------------HH--------------------------------H-H----------------------------------------H-H--------H----H-----H-----H------H-T?----------------------------?----S-----E----------------------------------------------------E---E--E--EET-H-H-H-------H-H---H-HH----H-H-----------------------HH-----H---?--ST------------TE--EE----------E--E----EES----??-?S??B?BTTBTTSB?H------------------------------------------------------------------------------------------------------------H-HH-H-----H-HHH--------------HHH---------------HHHHH----H----H-----HHHH-----------H--------H-------HHT--G----G-------------------GT???------------?--HHH-------------------------------HHHHHHHHHHS--------------------?HH-HH--HH-HHHH-----------------------------------------------------------------------HHH???---H----HH-H---HH--------?--------?---------S-?----E------EE--E-----E-----ETT-?S------------------------------S-S-----?-----------GG-G-TH------------------------HHH---H----H--H---S-----T--T---------?---------E---E---E------E--E-T-----T--?-?-TT----H---H-H---H---T-----H---H-H---H---HHH 1ZI9|A PF12700.2_HlyD_2_seed 70 691 !Q:1,1|8,9|19,25|27,28|36,37|40,40|44,45|49,51|54,54|57,57|60,60|67,76|79,268|271,271|280,338|340,342|345,349|352,352|355,357|362,362|364,364|367,374|382,383|385,389|396,403|405,408|410,410|415,433|440,440|448,449|461,462|465,468|480,480|485,485|510,510|515,620|629,629|643,647|652,653|661,678|682,683|686,686 Q:0,0|2,7|10,18|26,26|29,35|38,39|41,43|46,48|52,53|55,56|58,59|61,66|77,78|269,270|272,279|339,339|343,344|350,351|353,354|358,361|363,363|365,366|375,381|384,384|390,395|404,404|409,409|411,414|434,439|441,447|450,460|463,464|469,479|481,484|486,509|511,514|621,628|630,642|648,651|654,660|679,681|684,685|687,690 E?EEEEEE--EEEEEEEEE-------E--ESSEEEE??SS?EEE--EEE???TT?EE?TT?EEEEEE??????????EE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EE?SSSEEEEE-----------------------------------------------------------E???TT----?EE?TT???EEEE?T-TS--------EEEEEEE--E-----HHHHTT??------T----T?EEEE-------------------ESBSSG-GGEEEEE--EEEEEEEEETT--TT----EEEEEEEEESS?GGGS?TTBEEEEEEEEEEEEEEEEEEGGG?EEET----------------------------------------------------------------------------------------------------------TEEEEEEE-ETTTTEEEEEEEE-----EEEE--ETTEEEE------------------EES??TT?EEEE 2F1M|A PF12701.2_LSM14_seed 156 141 !Q:0,6|19,19|26,26|33,35|40,46|52,76|78,79|83,83|86,93|95,98|101,101|105,105|116,117|119,119|121,140 Q:7,18|20,25|27,32|36,39|47,51|77,77|80,82|84,85|94,94|99,100|102,104|106,115|118,118|120,120 ???????SSEEEEEEETTT-EEEEEE-EEEEET---TTTE-------EEEES---------------------????S??SSS?SS-----???S????SS?EEE?STTEEEEEES??S?S-------------------- 2VC8|A PF12702.2_Lipocalin_3_seed 17 123 !Q:0,5|17,17|26,26|36,36|44,63|66,67|85,86|100,100|107,112 Q:6,16|18,25|27,35|37,43|64,65|68,84|87,99|101,106|113,122 --????EEEEEEETTEE-EEEEEEEE?TTSBEEEES?SSEEEEE--------------------EE--EETTEEEEEEEEEETTE--EEEEEEEEEEEEE?SSEEEE------EETTEEEEEE 3HTY|A PF12704.2_MacB_PCD_seed 1392 714 !Q:0,14|16,17|19,21|26,31|33,36|38,39|41,42|46,52|55,55|58,58|61,63|65,65|68,69|73,91|94,100|102,172|174,175|177,177|180,180|184,187|190,201|204,204|206,206|208,208|213,214|217,220|223,224|227,244|251,264|272,285|291,308|310,311|313,313|315,315|320,331|333,338|340,345|347,347|351,357|360,360|362,364|369,378|381,383|387,387|389,389|392,392|396,396|400,400|403,420|423,423|425,426|430,460|462,466|468,472|475,498|503,505|509,576|587,611|616,616|618,652|655,655|662,670|672,672|676,679|683,700|702,702|709,712 Q:15,15|18,18|22,25|32,32|37,37|40,40|43,45|53,54|56,57|59,60|64,64|66,67|70,72|92,93|101,101|173,173|176,176|178,179|181,183|188,189|202,203|205,205|207,207|209,212|215,216|221,222|225,226|245,250|265,271|286,290|309,309|312,312|314,314|316,319|332,332|339,339|346,346|348,350|358,359|361,361|365,368|379,380|384,386|388,388|390,391|393,395|397,399|401,402|421,422|424,424|427,429|461,461|467,467|473,474|499,502|506,508|577,586|612,615|617,617|653,654|656,661|671,671|673,675|680,682|701,701|703,708|713,713 ------??------?S--T---TTST------T----S--S--SSE-------EE-EE-ES---S?TT-?HHH-------------------HH-------S?-------------------------------------------------------------------??-B--H-HH-HHH----HH------------TS-T-T-EEEE--EE----EE--EE------------------EEEEEE--------------TTEEEEE--------------EEEEE------------------E?-T-T-HHHH------------H------T--?--?E-EEE---????HH-H---HHHT--------??EE---EEE-H-HH-HHH-HHT-TS-?----------?-----TT?E--EEE-------------------------------T-----T-----EE------------------------EEEE---EEE-----??------------??---??------------------?????-?----------------?EEEEEHHHHH-------------------------HHTT?S-----------------------------------SB?SEEEEE---------E?TTS--?-HHH------------------H-HHHHHH----H 3FTJ|A PF12705.2_PDDEXK_1_seed 258 992 !Q:0,1|6,6|13,14|21,22|25,25|28,55|58,60|64,94|102,107|112,125|129,182|184,195|200,232|234,237|239,283|286,289|294,294|296,297|300,318|320,320|322,323|326,328|332,333|351,375|379,379|383,410|428,437|440,441|445,449|455,462|466,466|469,482|486,486|490,506|512,514|517,519|527,534|538,541|547,565|578,603|606,647|650,654|656,660|663,663|665,668|674,674|684,694|696,696|698,707|711,712|717,720|725,725|727,728|730,732|735,735|738,740|753,753|760,760|764,818|824,824|827,827|832,832|837,837|840,840|844,846|849,850|853,857|861,862|866,867|870,872|874,876|879,882|887,887|889,889|892,892|894,897|900,903|908,955|957,957|959,962|965,966|969,973|975,978|980,984 Q:2,5|7,12|15,20|23,24|26,27|56,57|61,63|95,101|108,111|126,128|183,183|196,199|233,233|238,238|284,285|290,293|295,295|298,299|319,319|321,321|324,325|329,331|334,350|376,378|380,382|411,427|438,439|442,444|450,454|463,465|467,468|483,485|487,489|507,511|515,516|520,526|535,537|542,546|566,577|604,605|648,649|655,655|661,662|664,664|669,673|675,683|695,695|697,697|708,710|713,716|721,724|726,726|729,729|733,734|736,737|741,752|754,759|761,763|819,823|825,826|828,831|833,836|838,839|841,843|847,848|851,852|858,860|863,865|868,869|873,873|877,878|883,886|888,888|890,891|893,893|898,899|904,907|956,956|958,958|963,964|967,968|974,974|979,979|985,991 ??BHHH-HHHHHH-?HHHHHH--HT-TS------------??????---------?SS?-?HHH-------------------------------HHHHHHH------HHHH--------------HHH------------------------------------------------------H------------HHHT---------------------------------T??--G---------------------------------------------GG?--?HHHH-H--HH-------------------H-H--HH---HHH--HGGGSTTTGGGTSHHHH-------------------------HHH-HHH----------------------------HHHHHHHHHHHHHHHTT??-------?EE--EEE-----EEEES--------SSS-SB??------------EEE-EET-----------------TTEEE---EE---BEEEEEE--------EEE----EETTE-------------------EEEEEEEEESSS?------------------??----?HH------------------------------------------HH-----H-----TT-S??--HHHHH-HHHHHHHHH-----------H-H----------HTS??EEEE----EEEE-E-?S???EE?SS???HHHHHHHHHHTT?BEEEEE?SHH-------------------------------------------------------HHHHH?TT?SSEE?SSBS?EE?TTS???TT??EE?----HHH--HHH--HH---H---HH----HHHH-H-HH-H----HH----HHTT?--------------------------------??----------???E-E?---SS??TT-----S----S----?TTHHHHT 4IC1|A PF12706.2_Lactamase_B_2_seed 268 667 !Q:2,3|8,9|11,51|60,60|64,66|69,71|74,75|81,87|89,89|91,102|107,110|120,122|124,151|156,173|185,246|257,257|263,264|268,268|270,279|282,282|287,359|363,366|368,368|370,375|380,382|387,395|399,399|403,425|430,464|468,468|470,471|477,477|479,480|482,484|487,522|524,531|535,541|543,570|573,588|595,597|609,609|611,621|627,629|631,633|637,638|647,647|649,650|653,654|657,661 Q:0,1|4,7|10,10|52,59|61,63|67,68|72,73|76,80|88,88|90,90|103,106|111,119|123,123|152,155|174,184|247,256|258,262|265,267|269,269|280,281|283,286|360,362|367,367|369,369|376,379|383,386|396,398|400,402|426,429|465,467|469,469|472,476|478,478|481,481|485,486|523,523|532,534|542,542|571,572|589,594|598,608|610,610|622,626|630,630|634,636|639,646|648,648|651,652|655,656|662,666 SE--EEES??T-----------------------------------------THHHHHHT?GGG???SS---SS??SEEEE-------E?S?---------??HHHH----GGGGGGGGG?-?E----------------------------EEEE?-----------------HHHHHHTTTTS?-------------------------------------------------------------HHHHHTTSTT?EEEEE??SSS?B--------??TT?TTEE-------------------------------------------------------------------------EEE----E-E??????TTST---TTTS??-------TTS-SEE-----------------------EEEE-----------------------------------ETT-T??EEEEE-S??S???HH------------------------------------H--------HHH-------H----------------------------TT---------------?SEEEEE???SSTTHHHHHTS?S-?--------?SSSSS???S---SSS--SSHHHHGG-G??SS--EE-----EEESB 2QED|A PF12707.2_DUF3804_seed 5 128 !Q:0,0|27,27|30,31|34,34|38,38|41,41|96,96|117,118|121,122|126,127 Q:1,26|28,29|32,33|35,37|39,40|42,95|97,116|119,120|123,125 ?HHHHHHHHHHHHSSTTTTTTHHHHHB?TT??EE?TTS?EE?HHHHHHHHTSSSEEEEEEEEEEEEEEEESSSSEEEEEEEEEEEEEETTEEEEEB?EEEEEEEEETTEEEEEEEEE??SB??GGG?? 3HZP|A PF12708.2_Pectate_lyase_3_seed 90 464 !Q:3,3|7,14|17,19|21,22|26,29|31,31|44,52|54,54|57,60|64,64|70,70|79,100|103,104|108,116|121,123|127,128|132,134|136,136|139,143|146,146|151,151|153,153|155,155|159,176|180,180|184,187|190,194|198,199|204,204|207,207|210,211|214,227|231,243|252,261|265,275|277,279|282,283|286,286|291,291|293,325|328,328|336,336|340,350|352,353|357,368|370,387|394,403|407,408|419,421|427,429|435,435|438,458|460,461 Q:0,2|4,6|15,16|20,20|23,25|30,30|32,43|53,53|55,56|61,63|65,69|71,78|101,102|105,107|117,120|124,126|129,131|135,135|137,138|144,145|147,150|152,152|154,154|156,158|177,179|181,183|188,189|195,197|200,203|205,206|208,209|212,213|228,230|244,251|262,264|276,276|280,281|284,285|287,290|292,292|326,327|329,335|337,339|351,351|354,356|369,369|388,393|404,406|409,418|422,426|430,434|436,437|459,459|462,463 EEE-GGG--------GT???E--EEE----E?HHHHHHHHHTTS--------?S?TT????SSS?EEEEE?SSEEEESS?---------------------EE??TTE---------EEEE--?SSS??EEE---E?TT??---SS?SEES-S?B?GGG?-----------------BSS?GGG???-EE-----EEE--EEEE?TT?SS-?EE--------------EEE???---------?SSEEEEEE----------EEE--------???S---TT??EE-EEEE?S---------------------??--------??EE-EEEEEES?SEE-----------E--EEE?-----------S----------------??EEEEEE----------EES-?SEEEEEEEBS?--EEEEE---EEEES?SE---------------------E--EE 2UVF|A PF12710.2_HAD_seed 272 689 !Q:3,4|9,17|21,21|37,48|62,64|68,87|92,230|232,232|235,245|251,252|255,284|291,291|294,296|300,301|305,376|386,389|392,393|401,403|406,419|423,425|428,428|430,431|439,447|449,452|459,470|473,476|480,481|483,484|488,488|491,491|493,579|586,588|592,592|597,597|599,602|610,614|621,640|643,643|645,654|656,657|661,662|668,670|674,677|679,679|681,682 Q:0,2|5,8|18,20|22,36|49,61|65,67|88,91|231,231|233,234|246,250|253,254|285,290|292,293|297,299|302,304|377,385|390,391|394,400|404,405|420,422|426,427|429,429|432,438|448,448|453,458|471,472|477,479|482,482|485,487|489,490|492,492|580,585|589,591|593,596|598,598|603,609|615,620|641,642|644,644|655,655|658,660|663,667|671,673|678,678|680,680|683,688 EEE??BTTT---------BSS?HHHHHHHHHHHTTSS------------SSHHHHHHHHHHH---HHH--------------------HHHT------------------------------------------------------------------------------------------------------------------------------------------?S?HH-----------HHHHH--HH------------------------------HHHHTS?HH---HHH--HHH------------------------------------------------------------------------HHHHHHTTG----GG??HHHHHHH---HH--------------HHH---TT?E--EEEEESS--------?H----HHHHHH------------HH----HTT??E--EEE?EE-E---------------------------------------------------------------------------------------EETTEE---EEE-EESS?S----STHHHHH-----HHHHHH--------------------HH-T----------T??GGG--SSEEE---EEE?--?G-G--GHHHHH 1RKU|A PF12712.2_DUF3805_seed 6 161 !Q:0,3|8,8|12,12|18,18|21,21|25,27|35,35|39,41|50,56|72,72|75,75|123,125|135,135|138,139|142,146|151,152 Q:4,7|9,11|13,17|19,20|22,24|28,34|36,38|42,49|57,71|73,74|76,122|126,134|136,137|140,141|147,150|153,160 ?-??EEEE?GGG?EEEEE?TT?EEE???TTEEEEE?SSS???EEEEEEEE------?STTHHHHHHHHHHHH?TT?EEEEETTEEEEEEEEEEEETTEEEEEEEEEEEETTEEEEEEEEEETT???HHHHHHHHH?EE??TT?????EEEE??HHHHHHHH 3HLZ|A PF12713.2_DUF3806_seed 25 98 !Q:13,13|15,15|18,18|21,26|28,28|45,45|48,48|66,67|70,70|74,76|89,92 Q:0,12|14,14|16,17|19,20|27,27|29,44|46,47|49,65|68,69|71,73|77,88|93,97 GGHHHHHHHHHTT?S?TT?HH------H-HHHHHHHHHHHHHHHS-TT?EEEEEEETTEEEEEEEE--TT-EEE?--HHHHTHHHHHTT????HHHHH 3HLZ|A PF12715.2_Abhydrolase_7_seed 4 395 !Q:0,3|8,13|17,18|33,35|38,40|43,44|64,75|83,83|94,95|100,100|111,114|116,116|124,125|128,129|136,138|144,146|150,150|152,152|155,155|165,165|171,172|179,179|190,191|204,205|224,224|251,251|254,255|262,262|264,265|273,277|281,284|287,287|291,292|299,300|312,312|316,316|318,318|320,320|336,336|343,345|349,349|354,357|360,361|364,365|375,376|380,380|382,383|395,395 Q:4,7|14,16|19,32|36,37|41,42|45,63|76,82|84,93|96,99|101,110|115,115|117,123|126,127|130,135|139,143|147,149|151,151|153,154|156,164|166,170|173,178|180,189|192,203|206,223|225,250|252,253|256,261|263,263|266,272|278,280|285,286|288,290|293,298|301,311|313,315|317,317|319,319|321,335|337,342|346,348|350,353|358,359|362,363|366,374|377,379|381,381|384,394 ????GGGS??????STT??BSSHHHHHHHHHHT???TT???TT??HHHHHHHHHHHHHHHHHHH????????-???EEEEEEE?SSEEEEEEEE??STTB?EEEEEEEESS?--?S?EEEEEEE??TT??HHHHHT???SSSTT??-STT?T-TT?HHHHHHTTT?EEEEE??TTSGGG?SSGGGTTTTS??HHHHHHHHHHTT??HHHHHHHHHHHHHHHHTT?SSEEEEEEEEEEEGGGHHHHHHHHHH?TT??EEEEES?B??HHHHHHH?????TTS????SS?GGG??TTHHHH??HHHHHHHTTTS?EEE?S?B?HHHHHHHHHHHHHHT?TTSEEE???GGG?SGGG????SS??SS??HHHHHHHTT??GGG?S??HHHHHHHHHHH- 3NUZ|A PF12717.2_Cnd1_seed 77 310 !Q:13,14|16,18|26,29|35,40|45,50|52,77|112,113|116,116|135,136|145,148|158,161|167,167|173,209|218,226|243,244|247,293 Q:0,12|15,15|19,25|30,34|41,44|51,51|78,111|114,115|117,134|137,144|149,157|162,166|168,172|210,217|227,242|245,246|294,309 SHHHHHHHHHHHT--T???GGGGTTT----HHHHH------HHTT-----?S--?-----------------------HHHHHHHHHHHHHHHTTTHHHHHHSSHHHHHHHH--TT?SSHHHHHHHHHHHHHHHH--HSTTTTSS-???TTHHHHHHH----HTTSS?STTHH-------------------------------------HHHHHHTT??-----??SHHHHHHHHHHHGGGS??SS-----------------------------------------------HHHHHHHHHHHHHHSS 2JKT|B PF12718.2_Tropomyosin_1_seed 41 150 !Q:100,102 Q:0,99|103,149 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH 3U59|A PF12723.2_DUF3809_seed 6 145 !Q:5,5|8,8|18,18|26,27|29,29|35,35|69,72|77,80|84,86|97,97|112,118|145,145 Q:0,4|6,7|9,17|19,25|28,28|30,34|36,68|73,76|81,83|87,96|98,111|119,144 EEEEE?TT?HHHHHHHHH?HHHHTTT??S?EEEEE?SSEEEEEEEEEETTTEEEEEEEEEEEEEETTEE----EEEE????TTB?--EEEEEEEEEE?GGGEEEEEEEEEEE???????HHHHHHHHHHHHHHHHHHHHHHHHHH- 3NQN|A PF12724.2_Flavodoxin_5_seed 70 211 !Q:5,5|16,18|22,24|32,33|43,47|50,50|53,55|59,59|62,63|69,69|72,72|78,78|82,86|92,93|96,96|104,104|106,112|121,129|131,133|136,137|139,144|148,149|152,153|155,156|158,169|171,172|174,174|176,187|189,189|191,193|197,199|203,207 Q:0,4|6,15|19,21|25,31|34,42|48,49|51,52|56,58|60,61|64,68|70,71|73,77|79,81|87,91|94,95|97,103|105,105|113,120|130,130|134,135|138,138|145,147|150,151|154,154|157,157|170,170|173,173|175,175|188,188|190,190|194,196|200,202|208,210 EEEEE?SSSHHHHHHH---HHH---HHHHHTT-?EEEEEEGGG--??-ST-TT---TTT?SE--EEEEE?EE?TTHHH-HHH-----TGGGS??TT?EEEEEEE-E?------TTSSSTTH---------H---HH--H------HHH--HH--H--H------------T--T?E------------E?S??-EEE---ESS?---?HHH 1BU5|A PF12727.2_PBP_like_seed 186 415 !Q:7,8|11,12|14,15|18,19|24,24|34,34|38,38|46,74|78,91|94,95|98,104|110,110|114,114|116,116|120,120|123,126|129,129|140,151|153,185|191,192|195,195|197,201|203,203|209,209|211,211|213,213|224,227|229,230|232,235|240,257|263,263|265,265|275,275|279,304|311,311|313,315|320,332|336,336|338,343|346,352|354,355|360,360|366,368|373,373|377,383|385,386|395,395|399,403 Q:0,6|9,10|13,13|16,17|20,23|25,33|35,37|39,45|75,77|92,93|96,97|105,109|111,113|115,115|117,119|121,122|127,128|130,139|152,152|186,190|193,194|196,196|202,202|204,208|210,210|212,212|214,223|228,228|231,231|236,239|258,262|264,264|266,274|276,278|305,310|312,312|316,319|333,335|337,337|344,345|353,353|356,359|361,365|369,372|374,376|384,384|387,394|396,398|404,414 HHHHHHH?-TT-?E--EE--EEES?HHHHHHHHH-TTS?SEEEESS--?-----------------------??-TTT--?----------?TT?-EE-------EEEEE-EEE-E-EEE?TT????EE?HHHHHHHHHT------------S-------------------------------??BGGGG--TS?S----?B?EEEEE?T-T?HHHHHHHHHH----T?-E----EEET------------------TEEEE?S?TTSEEESSH-HHH--------------------------HHHHHH?T---TEEE-------------EEE-G------GG?-----?T--TSEE?EETTB???HHHH-HTT?------S??EEEEEEEE?TTT-??--HHHHHHHHHHH 1IXG|A PF12728.2_HTH_17_seed 461 88 !Q:2,2|8,8|13,13|15,17|21,21|24,24|26,26|28,30|32,36|38,41|44,45|48,48|51,55|57,57|59,62|65,71|83,83|86,87 Q:0,1|3,7|9,12|14,14|18,20|22,23|25,25|27,27|31,31|37,37|42,43|46,47|49,50|56,56|58,58|63,64|72,82|84,85 EE?HHHHH-HHHT-S--?HHH-HH-H-H---H-----H----HT--SS?EE-----E?S----SS?------EEEEHHHHHHH?EE?? 4J2N|A PF12738.2_PTCB-BRCT_seed 49 77 !Q:0,0|7,8|12,15|28,28|31,31|35,36|38,42|44,45|50,52|56,56|68,69|73,73 Q:1,6|9,11|16,27|29,30|32,34|37,37|43,43|46,49|53,55|57,67|70,72|74,76 ?EEEEES??BTH----HHHHHHHHHHTT?EE?SSB-?T-----T??EEEE---SSS?SHHHHHHHHTT-?EEE?THH 2D8M|A PF12740.2_Chlorophyllase2_seed 21 338 !Q:0,6|13,13|15,17|25,26|29,30|35,36|54,88|93,94|104,106|108,110|118,120|123,123|154,158|161,180|188,207|209,216|218,220|222,222|231,231|235,245|257,260|264,278|281,285|292,294|301,302|304,313|329,332 Q:7,12|14,14|18,24|27,28|31,34|37,53|89,92|95,103|107,107|111,117|121,122|124,153|159,160|181,187|208,208|217,217|221,221|223,230|232,234|246,256|261,263|279,280|286,291|295,300|303,303|314,328|333,337 -------EEEESS?S?--EEEEEEE??TT??HHHH--HHHHHHHHTTTEEEEEE?-------------------?--------------SSTT??HHHHHHHHH---H---HHHHHHH---TS?HHHHTTEEEEEEEEEEETHHHHHHHHHHHH?----TT-------------------?SEEEEES???-----------------S??----??T??-S?EEEEEETT?SSS?----------TTTTHHHHHHT?--?TTS--------------?EE-----EEEETT-??TTGGGS??H----------HHHHHHHHHHHHHHS??--GGGHH 3F98|A PF12741.2_SusD-like_seed 5 594 !Q:0,51|68,68|70,70|74,74|101,102|107,107|113,115|121,122|149,150|177,177|181,184|187,187|189,189|192,193|196,196|222,222|226,230|235,235|238,238|242,246|270,270|284,285|288,291|296,296|307,307|309,309|319,326|342,342|350,364|367,370|372,372|375,380|388,396|398,400|403,404|409,409|421,421|426,429|432,432|450,451|461,462|464,468|470,471|474,474|478,478|480,481|483,486|489,490|494,494|499,499|514,514|526,527|529,533|535,538|541,546|551,551|553,559|581,582|587,588|591,592 Q:52,67|69,69|71,73|75,100|103,106|108,112|116,120|123,148|151,176|178,180|185,186|188,188|190,191|194,195|197,221|223,225|231,234|236,237|239,241|247,269|271,283|286,287|292,295|297,306|308,308|310,318|327,341|343,349|365,366|371,371|373,374|381,387|397,397|401,402|405,408|410,420|422,425|430,431|433,449|452,460|463,463|469,469|472,473|475,477|479,479|482,482|487,488|491,493|495,498|500,513|515,525|528,528|534,534|539,540|547,550|552,552|560,580|583,586|589,590|593,593 --------------------?-----------????????????????????GGGGTHHHHHHHTTTT?B?TTT?SHHHHHHHHHTTTTHHHHTTSEEESS??HHHH?SGGGT???HHHHH--HHHHHHHHHHHHHHHHHHHHHHSSSS??HHHHHHHHHHHHHHHHHHHHHHSSEE?TTT----TS-S?SS??EE?HHHHHHHHHHHHHHHHHHHHHHHTT?SBS-----STTT?TT-TTT-----BHHHHHHHHHHHHHHHHHHTTTT?HHHHHHHHHHHHH-?TT????SGGG?EEESEETTEE?B?HHHHHHHTS?------?EEEBHHHHHHHHHTT?TTHHHHB??-------------TT????B?SS??--??TTTTTTS?-------?B???TT??EEEE?HHHHHHHHHHH-HHTT?-??SS?HHHHHHHHHHHHHHHTT??HHHHHHHHT??S?????B??SS?GGG?B??S????SS??TTS?HHHH-HHHHHHHHHHHSTT?HHHHHHHHHHH??S?????S????SS??????SSSS?S???????HHHHHHSHHHHHHHHHHHSTT??STTS??TT??S 3EHM|A PF12744.2_ATG19_autophagy_seed 10 267 !Q:0,87|90,92|111,111|115,117|120,120|123,125|131,140|143,144|146,149|152,153|159,163|165,170|173,174|179,179|189,191|195,195|198,200|202,211|213,266 Q:88,89|93,110|112,114|118,119|121,122|126,130|141,142|145,145|150,151|154,158|164,164|171,172|175,178|180,188|192,194|196,197|201,201|212,212 ------------------------------------------------??------------------------????---------?SS???EEEEEEEETTEEEEEEEE?SSS???SS?EE???SSSSS?????-----EE??S????TT??EEEEE----?S??????TT??EEEE?TTSSEEEEE???SSS?EE???S----------S?----------------?-------------???-------------------- 2KZB|A PF12746.2_GNAT_acetyltran_seed 2 269 !Q:5,9|17,17|19,21|39,39|43,44|63,68|110,110|112,117|129,129|137,138|168,169|200,200|225,225|229,229|245,246|255,265|268,268 Q:0,4|10,16|18,18|22,38|40,42|45,62|69,109|111,111|118,128|130,136|139,167|170,199|201,224|226,228|230,244|247,254|266,267 HHHHH-----HHHHHHH?S???HHHHHHHHSSSSEEEES?SSS??EEEEEEESSSEEEEEEES??----HHHHHHHTTSSEEEEESSHHHHHHHHHHHGGGEEEEEEEEE?S???-??HHHHHHHHHTS?TTSEEEE??HHHHHHHHHSTTTGGGTTTSSSHHHHHHH??EEEEEETTEEEEEEEEEEEETTEEEEEEEE?GGGTTSSHHHHHHHHHHHHHHHTT?EEE?EESSHHHHHHHHHHT??EEEEEEEE-----------EE? 2JLM|A PF12747.2_DdrB_seed 6 166 !Q:0,11|18,18|21,22|46,64|66,66|68,70|77,77|85,85|91,91|93,93|117,118|127,128|136,137|141,141|145,145|147,148|152,154|162,162|165,165 Q:12,17|19,20|23,45|65,65|67,67|71,76|78,84|86,90|92,92|94,116|119,126|129,135|138,140|142,144|146,146|149,151|155,161|163,164 ?-----------EEEEEE?TT??EEEEEESSGGGHHHHHHHHHTTT------------------?B?S???TTSEEE?GGGSTTB?GGGGT?E-EEEETTTEEEEEETTEEEEEEEE??EEETTEEE??EEEEEEE??TTS?GGG?B??TTS??-EEEEEEE?SS? 4EXW|A PF12753.2_Nro1_seed 18 516 !Q:0,14|34,64|85,85|107,122|124,124|127,136|139,139|163,170|173,173|176,177|196,196|198,199|201,201|225,225|231,243|245,245|256,266|278,279|283,285|287,313|315,316|338,338|351,377|385,385|390,390|411,418|424,425|429,430|459,460|478,478|480,480|484,484|504,507 Q:15,33|65,84|86,106|123,123|125,126|137,138|140,162|171,172|174,175|178,195|197,197|200,200|202,224|226,230|244,244|246,255|267,277|280,282|286,286|314,314|317,337|339,350|378,384|386,389|391,410|419,423|426,428|431,458|461,477|479,479|481,483|485,503|508,515 ???--??????????HHHHHHHHHHHHHHHHHHH???????????????????????????????HHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHHHHT?---------------S?GG----------GS?HHHHHHHHHHHHHHHHTHHHHGG--------GS?SS??HHHHHHHHHHHHHHHTTS?S??H-HHHHHHHHHHHHHHHHHHHHHHH?GGGTT-------------S?HHHHHHHHHH-----------HHHHHHHHHHS--TTS???T---------------------------T??TGGGTTHHHHHHHHHHTGGGS?HHHHHHHHHHHH---------------------------HHHHHTT?STTS?HHHHHHHHHHHHHHHHHHHH--------HHHHH--HHS??TTHHHHHHHHHHHHHHHHHHHHHHHHHS??TTHHHHHHHHHHHHHHH?S?HHH-HHHHHHHHHHHHHHHHHTT????HHHHHHHH 3MSV|A PF12763.2_EF-hand_4_seed 13 107 !Q:0,0|3,9|22,23|27,28|42,43|55,55|58,58|62,63|79,80|83,86|89,90|95,95|98,106 Q:1,2|10,21|24,26|29,41|44,54|56,57|59,61|64,78|81,82|87,88|91,94|96,97 -HH-------HHHHHHHHHTTS??SSS??BHHHHHHHHHTTT??HHHHHHHHHHH?SS?SSB??HHHHHHHHHHHHHHH--HT????SS??TTTS?TT?------?? 1MUX|A PF12766.2_Pyridox_oxase_2_seed 60 156 !Q:0,1|15,18|21,21|33,34|36,36|39,44|52,54|56,56|59,88|91,92|109,123|125,128|131,132|155,155 Q:2,14|19,20|22,32|35,35|37,38|45,51|55,55|57,58|89,90|93,108|124,124|129,130|133,154 ??TTHHHHHHHHHHT----TT?GGGGEEEEEEE?-T-TS?-----EEEEEEE???B?TT------------------------------SS?-EEEEEETTSHHHHHHH---------------H--??EE--EEEEEETTTTEEEEEEEEEEEE? 1T9M|A PF12771.2_SusD-like_2_seed 5 562 !Q:0,38|52,56|72,73|79,81|83,85|93,100|113,114|116,116|119,137|161,162|167,178|180,180|202,206|209,216|222,222|244,244|264,267|272,272|276,278|283,283|285,285|290,294|312,312|320,322|330,331|334,334|338,340|342,342|346,346|348,349|355,361|363,363|369,369|372,374|379,379|396,396|398,398|400,400|442,460|464,465|482,482|498,499|501,505|508,524|526,527|550,552|555,557 Q:39,51|57,71|74,78|82,82|86,92|101,112|115,115|117,118|138,160|163,166|179,179|181,201|207,208|217,221|223,243|245,263|268,271|273,275|279,282|284,284|286,289|295,311|313,319|323,329|332,333|335,337|341,341|343,345|347,347|350,354|362,362|364,368|370,371|375,378|380,395|397,397|399,399|401,441|461,463|466,481|483,497|500,500|506,507|525,525|528,549|553,554|558,561 ----------------------?????????????????THHHHHHHHHHHH?--??SGGGTTTTSEEESSS??TTTTT???B???THHHHHH--------HHHHHHHHHHHH--T?HH-------------------HHHHHHHHHHHHHHHHHHHHSSB??TTTT????????????B?HHHHHHHHHHHHHHHHHHHHT?????TT-------?TTTTT?HHHHHHHHHHHHHHHHHHTTT?SEETTEEHHHHHHHHHHHS????SGGG?EEE???SSTT?S?TTTT??--?TTEEEBHHHHHHHHHTT?TTHHHHB???HHHHHTT??TT?GGG???B?TTS?S??HHHHH???????B?GGGTS?SS???EEEE?HHHHHHHHHHHHHTTS-S?S?HHHHHHHHHHHHHHHHHHHSGGGGGGSSHHHHHHHTTSTTT?------------------GGG??SHHHHHHHHHHHHHTT?SSSSTTHHHHHHHHH??S?????TT????----------???B??HHHHHHSHHHHHHHHHHHHSTT???TT???GGGS 3EHM|A PF12774.2_AAA_6_seed 3 231 !Q:0,6|8,14|32,32|38,38|57,58|64,64|67,69|85,85|96,96|118,118|122,127|130,131|134,134|139,139|141,143|147,149|151,151|163,164|166,167|181,181|183,183|203,205|208,210|228,230 Q:7,7|15,31|33,37|39,56|59,63|65,66|70,84|86,95|97,117|119,121|128,129|132,133|135,138|140,140|144,146|150,150|152,162|165,165|168,180|182,182|184,202|206,207|211,227 ???????S???????HHHHHHHHHHHHHHHTT?EEEEE?STTSSHHHHHHHHHHHTT??EEEEE?SS???HHHHHHHHHHHHHHT?EEEEETTTSS?HHHHHHHHHHHHHHHHHHHHT?SEE??????EE??TT?EEEE?B???GGG???S?HHHHTTEEEEE??S??HHHHHHHHHHTTT?S?HHHHHHHHHHHHHHHHHSS???TT???SHHHHHHHHHHHHHHHH??? 4AKH|A PF12775.2_AAA_7_seed 3 272 !Q:0,3|8,8|11,15|33,35|56,56|61,62|67,69|72,73|91,91|99,99|110,114|118,119|154,155|160,164|171,172|176,180|190,192|202,202|228,228|230,230|236,239|259,261 Q:4,7|9,10|16,32|36,55|57,60|63,66|70,71|74,90|92,98|100,109|115,117|120,153|156,159|165,170|173,175|181,189|193,201|203,227|229,229|231,235|240,258|262,271 ????STTT?TT?????HHHHHHHHHHHHHHHTT???EEESSTTSSHHHHHHHHGGG?TTEE--EEEE???TT??HHHHHHHHHHHEEEETS?EEEEESS?EEEEEETTTT?????TTS??HHHHHHHHHHHHSEEEETTTTEEEEESSEEEEEE??TTTT?????HHHHTT??EEE?????HHHHHHHHH---HHHHHHTTS?GGGTTSHHHHHHHHHHHHHHHHHHS?T-TTSTT????HHHHHHHHHHHHHHHHTSS???TTHHHHHHHH 4AKH|A PF12777.2_MT_seed 3 344 !Q:0,0|57,57|100,101|111,111|114,115|130,131|133,139|149,151|161,162|164,166|180,180|183,184|192,192|212,234|327,327|336,336|344,344 Q:1,56|58,99|102,110|112,113|116,129|132,132|140,148|152,160|163,163|167,179|181,182|185,191|193,211|235,326|328,335|337,343 -HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHT-SGGGGGTTTHHHHHTHHHHHHHHHHGGGTSTHHHHHHHHHHS??HHHHHHHHH?SS??HHHHHHHHHHHHHT--T??--???HHHHHHGGG?--TTHHHHHHT??T???TTTHHHHHHHTTT?TT??HHHHHHH?TTHHHHHHHHHHHHHHHTT???????????????????????SGGGHHHHHHHHHHHHHHHTTSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTGGGS?HHHHHHHH-HHHHHHH- 3J1U|A PF12780.2_AAA_8_seed 3 268 !Q:1,12|31,32|56,56|60,68|87,89|99,99|116,117|122,122|142,145|161,162|168,168|176,181|196,197|209,211|214,217|226,227|247,252 Q:0,0|13,30|33,55|57,59|69,86|90,98|100,115|118,121|123,141|146,160|163,167|169,175|182,195|198,208|212,213|218,225|228,246|253,267 T????????????HHHHHHHHHHHHHHTSTT??EEEEESTTSSHHHHHHHHHHHTT?EEE?????????HHHHHHHHHHHHHHHHTS???EEEEEEGGG?SSTHHHHHHHHHHHHS??TTSS?TTTHHHHHHHHHHHHHHTT????HHHHHHHHHHHHTTT??EEEEE?TTSTTTT??????THHHHHSEEEEEES??HHHHHHHHHHH???TT????HHHHHHHH??HHHHHHHHHHHHHHHHSSS??????HHHHHHHHHHHHHHH 4AKH|A PF12781.2_AAA_9_seed 3 228 !Q:3,3|15,16|31,31|34,34|39,39|55,66|78,79|82,122|128,129|132,135|147,150|167,167|205,205|209,209 Q:0,2|4,14|17,30|32,33|35,38|40,54|67,77|80,81|123,127|130,131|136,146|151,166|168,204|206,208|210,227 HTS?HHHHHHHHHTT??SSHHHHHHHHHTTS?SS?EEEE?TTSHHHHHHHHHTGG????????????HHHHHHHHHHT??EE????-????????????????????????????????????EEEEE??TT????HHHHHTSEEEE????HHHHHHHHHHHHHHHH?HHHHHHHHHHHHTTHHHHHHHHTTTHHHHHHHHTTSS?GGG?HHHHHHHHHHHHHHHHHH 4AKH|A PF12790.2_T6SS-SciN_seed 149 221 !Q:0,39|49,49|52,52|54,55|57,59|62,65|75,76|83,83|88,89|93,95|106,106|113,113|115,115|118,118|122,122|125,140|144,144|147,148|155,156|158,158|161,162|164,164|166,167|173,174|178,202|206,210|216,216 Q:40,48|50,51|53,53|56,56|60,61|66,74|77,82|84,87|90,92|96,105|107,112|114,114|116,117|119,121|123,124|141,143|145,146|149,154|157,157|159,160|163,163|165,165|168,172|175,177|203,205|211,215|217,220 ????????-------------------?????????-???EEEEEEEEE?TT?S??T---TS????EEEEEEEES??HHHHHS?HHHH--HHS---HHHHHGGGEE-EEEEEE-E?TT?EEE-EE----------------EEE?TT??EEEEEE??S?GG--G?B-?EEEEE??TTS-------------------------EEE-----EEEEE?SSBE 3RX9|A PF12796.2_Ank_2_seed 620 591 !Q:2,2|7,9|11,12|14,25|27,28|30,30|32,41|43,43|45,48|51,71|73,75|77,80|83,96|99,119|122,165|167,168|171,171|173,178|180,184|186,201|203,222|224,225|227,229|231,236|238,312|314,315|320,328|330,330|333,395|398,405|407,419|421,444|448,449|451,478|482,494|496,505|508,525|528,531|533,535|537,538|541,549|551,551|553,553|556,556|558,558|560,574|576,580|582,582|584,590 Q:0,1|3,6|10,10|13,13|26,26|29,29|31,31|42,42|44,44|49,50|72,72|76,76|81,82|97,98|120,121|166,166|169,170|172,172|179,179|185,185|202,202|223,223|226,226|230,230|237,237|313,313|316,319|329,329|331,332|396,397|406,406|420,420|445,447|450,450|479,481|495,495|506,507|526,527|532,532|536,536|539,540|550,550|552,552|554,555|557,557|559,559|575,575|581,581|583,583 HH-HHHH---H--T--?---------H--H-H----------H-H----HH---------------------H---H----HT-------?-----?TT???------------------TT--------------------------------------------S??HH-H------H-----H----------------H--------------------H--H---T?-----H---------------------------------------------------------------------------H--HHHH---------H-HH---------------------------------------------------------------TT---?-?--T-------------T???---------------------TTS??H----------------------------HHH-------------H----------HH------------------TT?---H---H--HH---------H-H-HH-H-T---------------T--?-?T-T----??? 1BI8|B PF12797.2_Fer4_2_seed 423 54 !Q:5,9|12,13|15,30|32,33|35,37|40,41|43,51 Q:0,4|10,11|14,14|31,31|34,34|38,39|42,42|52,53 SSEEE?----TT--T---?---??---?--?H--H---HH--H?--------TT 1FCA|A PF12798.2_Fer4_3_seed 447 38 !Q:0,3|5,6|8,11|19,21|25,25|28,28|30,31|33,35|37,37 Q:4,4|7,7|12,18|22,24|26,27|29,29|32,32|36,36 ?--?T--T----HHHHTTT???HHH-HH?T--T---S? 2VPX|B PF12799.2_LRR_4_seed 569 187 !Q:1,2|4,5|9,17|19,21|23,50|52,56|58,68|70,71|73,76|78,89|91,94|96,101|104,108|110,126|128,132|134,168|170,172|174,176|178,180|182,185 Q:0,0|3,3|6,8|18,18|22,22|51,51|57,57|69,69|72,72|77,77|90,90|95,95|102,103|109,109|127,127|133,133|169,169|173,173|177,177|181,181|186,186 T--T??EEE------??-S---S------?----?---?---?-----?--G-----G-----------G--T----T--------?---T----T----??EE-----E---?---?---------S-----S-?--?----?-------?----------?------G---G---G---T----T 2A0Z|A PF12800.2_Fer4_4_seed 187 70 !Q:1,3|6,35|37,41|44,44|47,49|51,67|69,69 Q:0,0|4,5|36,36|42,43|45,46|50,50|68,68 T---TT------?-----?-----?------??---H-----HH-HH--?T-----------------T? 1BWE|A PF12802.2_MarR_2_seed 266 105 !Q:1,5|7,8|18,18|22,22|25,47|55,56|60,61|63,63|76,77|82,90|94,97|100,100|103,103 Q:0,0|6,6|9,17|19,21|23,24|48,54|57,59|62,62|64,75|78,81|91,93|98,99|101,102|104,104 G-??--T--TTHHHHHHH-HHH?SS?-------------------?--BHHHHHH--HHT??H-HHHHHHHHHHHH--TTSE---------EEE--??BT-TB?S 3K0L|A PF12804.2_NTP_transf_3_seed 571 738 !Q:4,23|25,29|32,50|52,61|63,72|75,76|78,85|89,95|97,97|99,103|105,115|117,119|126,126|130,141|145,154|156,185|190,196|199,201|204,216|218,219|221,221|223,227|229,262|264,275|277,288|290,300|302,306|308,319|322,337|341,344|347,349|355,391|393,396|398,416|418,420|423,435|438,439|445,446|449,453|457,457|465,480|482,492|494,507|509,518|521,522|525,525|527,537|539,540|542,599|602,602|604,604|607,610|613,614|616,620|624,626|628,630|632,642|645,645|648,651|653,653|656,661|664,665|667,690|692,698|701,703|706,706|708,721|724,724|726,730|732,735 Q:0,3|24,24|30,31|51,51|62,62|73,74|77,77|86,88|96,96|98,98|104,104|116,116|120,125|127,129|142,144|155,155|186,189|197,198|202,203|217,217|220,220|222,222|228,228|263,263|276,276|289,289|301,301|307,307|320,321|338,340|345,346|350,354|392,392|397,397|417,417|421,422|436,437|440,444|447,448|454,456|458,464|481,481|493,493|508,508|519,520|523,524|526,526|538,538|541,541|600,601|603,603|605,606|611,612|615,615|621,623|627,627|631,631|643,644|646,647|652,652|654,655|662,663|666,666|691,691|699,700|704,705|707,707|722,723|725,725|731,731|736,737 EEEE???------?---?------S-----SS-----------?-------S----------S?---------GG--G--------SEE-------T-T-----E-----------E---HHHHHH-HHH------------HHH-------?--S-----------------------------?EEEE----?--SS---SH-------------H--H-H-----H----------------------------------T------------T------------S-----??----E-----E??--------?-TT---?-??---------SHH----HH---HHHHH-------------------------------------H----H----?--------?-----S---SE-------------EE--EEETT-?TT---??TTH-HHHHHHT?---------------T-----------T-----------?--S----------EE--EE-E-?---------S--S--?-------------------------------------------------------EE-E-EE----EE--E-----ETT---H---H-----------HH-HH----H-HH------HT--T----?---------?--?------H-------HH---HH-H--------------HT-T----?E----EE 1HV9|A PF12822.2_DUF3816_seed 172 410 !Q:3,16|31,39|41,49|53,55|58,62|70,71|74,78|83,83|94,96|105,157|161,161|166,183|199,202|206,207|211,211|217,277|296,301|307,309|315,383 Q:0,2|17,30|40,40|50,52|56,57|63,69|72,73|79,82|84,93|97,104|158,160|162,165|184,198|203,205|208,210|212,216|278,295|302,306|310,314|384,409 HHH--------------HHHHHHHHHHHHTT---------T????----?TTS--?SS??-??GGGHHHH--HH-----HTTS?HHHHHHHHHH---HHHHHHHH-----------------------------------------------------TTT?SSHH------------------HHHHHHHHHHHHHHH----HHH--SSS?SHHHH-------------------------------------------------------------HHHHHHHHHHHHHHHHHH------HTTTT---THHHH----------------??????????----------------------------------------???HHHHHHHHHHHHHHHHHHHHHHHHHH 3P5N|A PF12826.2_HHH_2_seed 72 70 !Q:3,4|7,9|12,12|15,16|28,29|37,38|48,49|62,62 Q:0,2|5,6|10,11|13,14|17,27|30,36|39,47|50,61|63,69 HHH--HH---TT?TT??HHHHHHHHHHH?-SHHHHHT??HHHHTTSTT??HHHHHHHHHHHT?HHHHHHH 1X2I|A PF12827.2_Peroxin-22_seed 17 207 !Q:0,14|19,20|27,32|54,68|80,80|89,89|92,110|120,121|126,160|162,162|167,176|178,178|181,195|200,200|206,206 Q:15,18|21,26|33,53|69,79|81,88|90,91|111,119|122,125|161,161|163,166|177,177|179,180|196,199|201,205 ----???????????EEEE??HHHHTS---???GGGTTTSSEEEEEETTTSSSS?-------------?HHHHHHHHTTT?GGGEEEES?HH-------------------HHHHHHHHH??SEEE-----------------------------------E?GGGT??????????S?TT---------------GGGT?SEEEE? 2Y9M|B PF12831.2_FAD_oxidored_seed 240 961 !Q:5,6|22,27|32,34|37,44|49,49|55,98|101,102|108,174|190,193|196,197|199,207|218,229|234,237|245,247|249,270|272,274|278,278|281,288|290,298|300,301|304,306|319,331|335,392|395,396|403,441|447,453|457,460|464,470|474,474|476,476|481,482|485,500|514,565|569,602|606,620|622,623|626,628|631,638|649,673|678,681|689,701|703,703|707,716|726,726|729,739|743,751|753,761|766,771|773,774|780,781|784,784|786,787|789,791|795,795|799,820|822,823|827,839|842,842|844,853|859,860|862,866|872,872|874,874|879,880|887,889|905,960 Q:0,4|7,21|28,31|35,36|45,48|50,54|99,100|103,107|175,189|194,195|198,198|208,217|230,233|238,244|248,248|271,271|275,277|279,280|289,289|299,299|302,303|307,318|332,334|393,394|397,402|442,446|454,456|461,463|471,473|475,475|477,480|483,484|501,513|566,568|603,605|621,621|624,625|629,630|639,648|674,677|682,688|702,702|704,706|717,725|727,728|740,742|752,752|762,765|772,772|775,779|782,783|785,785|788,788|792,794|796,798|821,821|824,826|840,841|843,843|854,858|861,861|867,871|873,873|875,878|881,886|890,904 EEEEE??SHHHHHHHHHHHHTT?----?EEEE?--SS--------SSSS-GGGGG--------------------------------------------SS??EETTE-------------------------------------------------------------------EHHHHHHHHHHHHHH----ST--T---------EEEESSEEEE------------EEET----TTEEEEE---E----------------------E?--STT?SS-----???T---------T??SE---EEEEEEEEEEEE???----------EEE?----------------------------------------------??-------??BT??STTEEE---------------------------------------HHHHH-------HHH----HTT------?EES?S-SEEE--EE----------------SSTTHHHHHHHHG----------------------------------------------------GGT?--------------------------------?SEE---------------E--ES?--SS??------HHHHHHHHTT?-----?------------------EEET----EEEEEEE-------------E?TTS?---------EEEEEEEEE?TT---------??EEE---------E---------EEEE-----?S--EEEEE??EE-E??H---HHH-HTT--------------------??E--EEE-------------TT-T----------TEEEE-?S?---?TTEEE?G-GGGT??SHHHHH---HHHHHHHHHHHHHTT---?---?----?????-------------?-???-------?----------??? 2GAG|A PF12832.2_MFS_1_like_seed 39 79 !Q:28,28|32,34|64,64|66,67 Q:0,27|29,31|35,63|65,65|68,78 HHHHHTTTTHHHHHHHTTTTTSSHHHHH-HHH???HHHHHHHHHHHHHTTTSSHHHHHHHHGGG?S??SHHHHTTTTSS 2CFP|A PF12833.2_HTH_18_seed 512 113 !Q:6,7|17,17|21,21|23,23|25,25|43,45|47,52|54,72|74,74|77,78|85,85|102,102|107,109 Q:0,5|8,16|18,20|22,22|24,24|26,42|46,46|53,53|73,73|75,76|79,84|86,101|103,106|110,112 HHHTTT??HHHHHHHHH-HHH-S-S?HHHHHHHHHHHHHHHHH---H------H------?---?---?--?-H-HH--HHHHTT?SSHHHHHHHHHHHHSS?HHHH---HHH 1D5Y|A PF12836.2_HHH_3_seed 335 82 !Q:4,4|6,11|15,16|22,22|24,24|26,26|28,28|30,34|48,48|50,55|63,63|68,69|81,81 Q:0,3|5,5|12,14|17,21|23,23|25,25|27,27|29,29|35,47|49,49|56,62|64,67|70,80 HHTT?B-----?TTT??HHHHH-T-S-T-T?--?-HHHHHHHHHHHHH-H--?-??SSGGGGG-GSSS??HHHHHHHTTTB? 3PRR|U PF12837.2_Fer4_6_seed 236 58 !Q:4,5|9,25|28,29|31,32|36,38|40,44|46,56 Q:0,3|6,8|26,27|30,30|33,35|39,39|45,45|57,57 SEEE?-TTT?-?-------?---?--ST--T--TTT--?T-----T----?-----?B 2C3M|A PF12838.2_Fer4_7_seed 464 399 !Q:1,31|34,35|37,38|41,92|94,100|102,106|108,108|110,120|122,124|126,141|143,157|159,168|170,196|199,219|225,225|231,256|258,260|262,264|266,269|271,273|275,277|279,362|364,374|378,386|388,390|392,393|395,396|398,398 Q:0,0|32,33|36,36|39,40|93,93|101,101|107,107|109,109|121,121|125,125|142,142|158,158|169,169|197,198|220,224|226,230|257,257|261,261|265,265|270,270|274,274|278,278|363,363|375,377|387,387|391,391|394,394|397,397 S?-------?-----?---?------?-----HH--H--HH--?-------------------------------------------------T-------T?--?-E-E-----------E---E----------------E---------------E-----??-?-S---------------------------SS---------------?-----SSSSS?EEEEE--------------------------E---E---E----T---T---T----------?------?-------------?----------------?-------------------------?---------H-----------HHH---------H--?S--S--S? 2C3M|A PF12840.2_HTH_20_seed 108 102 !Q:4,7|10,14|18,18|29,45|48,49|51,51|60,64|66,73|77,77|83,83|89,89|93,93 Q:0,3|8,9|15,17|19,28|46,47|50,50|52,59|65,65|74,76|78,82|84,88|90,92|94,101 HHHH----HH-----HHS-HHHHHHHHHH-----------------TT??B?HHHHHHHH-----T------??HHH-HHHHH-HHHHH-TTS-EEEEEEEE 1R1U|A PF12844.2_HTH_19_seed 149 109 !Q:0,0|11,12|14,19|26,32|36,47|58,61|63,66|68,72|77,83|92,94|97,100|103,108 Q:1,10|13,13|20,25|33,35|48,57|62,62|67,67|73,76|84,91|95,96|101,102 ?HHHHHHHHHH--T?-?---HHHHHH-------HHT?-----?-----HHHHHHHHTT----S????B-----HHHH-------HHHHHHTT??-HH----HH?????? 3U3W|A PF12846.2_AAA_10_seed 149 798 !Q:0,2|7,8|19,19|23,24|32,61|66,71|75,77|81,85|90,112|115,115|122,132|137,154|158,224|242,242|244,245|247,261|271,272|282,295|298,299|304,304|308,442|444,445|453,454|462,462|465,503|511,522|529,530|532,538|547,550|552,568|574,575|578,578|585,597|614,615|621,655|657,663|666,666|670,680|685,685|689,690|692,698|700,702|717,717|722,722|730,730|732,732|742,751|761,761|767,767|769,770|772,773|779,784|790,792|794,795 Q:3,6|9,18|20,22|25,31|62,65|72,74|78,80|86,89|113,114|116,121|133,136|155,157|225,241|243,243|246,246|262,270|273,281|296,297|300,303|305,307|443,443|446,452|455,461|463,464|504,510|523,528|531,531|539,546|551,551|569,573|576,577|579,584|598,613|616,620|656,656|664,665|667,669|681,684|686,688|691,691|699,699|703,716|718,721|723,729|731,731|733,741|752,760|762,766|768,768|771,771|774,778|785,789|793,793|796,797 ???EEEE??TTSSHHHHHH-HHH--HHHHTTT----------------------------??EEEE------ESS-??SHH-----HHHH-----------------------TT?EEEETT-----------SGGG----------???-----TTS???????????????-------------------------------------------------???HHHHHHHHHHHHHHHHS?S??H---------------HHHHHHHHH--HHHHHHHTT------------??TT??GGGS?GGG---------------------------------------------------------------------------------------------------------------------------------------S??HHHHHHH--HHHHTTT?HH---------------------------------------HHHHHHH------------HHHHHH--T-------STTHHHHS----S??????----------?SSEEE--EE?GGGTTS------------?HHHHHHHHHHHHHHHH--HHHHH-----------------------------------S-----??TT?EEE-----------ETTG-GGG??T-------T?--THHHHHHHHHHHHG-GGGT?EEEEEES?G-GGGGSTTTH----------HHHHHHHHS?SEEEE?S??H--HHHHH------HHHHT---T??HH 4AG6|A PF12847.2_Methyltransf_18_seed 195 366 !Q:3,4|7,7|16,17|21,23|29,35|42,43|48,57|59,65|74,99|103,139|142,142|145,145|147,150|155,159|162,183|186,191|197,198|200,236|239,252|256,258|261,273|277,298|301,302|306,309|312,346|348,348|350,350|352,359|365,365 Q:0,2|5,6|8,15|18,20|24,28|36,41|44,47|58,58|66,73|100,102|140,141|143,144|146,146|151,154|160,161|184,185|192,196|199,199|237,238|253,255|259,260|274,276|299,300|303,305|310,311|347,347|349,349|351,351|360,364 TTE--EE-EEESTTTT--HHH---HHHHT-------TSSSEE--EEEE---------?S------?HHHHHHHH--------------------------HHH-------------------------------------HT-TT?T----TSEE-----EE?--------------------?TT------GGGGG??S----?-------------------------------?SE--------------EEE???TT------------?TTH----------------------HH--HHH----HT??---------------------------------T-T?E--------EEEEE? 3OZS|A PF12848.2_ABC_tran_2_seed 246 124 !Q:6,6|9,9|14,15|51,76|79,79|89,92|94,97|102,106|108,108|110,113|116,117|119,120 Q:0,5|7,8|10,13|16,50|77,78|80,88|93,93|98,101|107,107|109,109|114,115|118,118|121,123 EEESSS?EE-EEES-?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??-?-------------????----?TT-TTTTTHHHH----T?---HHHH-----H-H----GG--G--SSB 4FIN|A PF12849.2_PBP_like_2_seed 148 778 !Q:0,6|9,56|71,74|76,76|82,94|99,99|101,132|134,144|147,162|164,166|170,170|183,217|224,231|243,265|271,280|293,294|297,321|324,325|327,328|330,330|341,420|425,426|430,433|435,436|438,444|451,495|500,518|522,574|576,579|585,587|589,601|613,616|618,627|633,637|645,660|663,664|666,696|698,702|706,714|716,724|732,734|740,740|744,744|746,747|750,754|761,767|774,774 Q:7,8|57,70|75,75|77,81|95,98|100,100|133,133|145,146|163,163|167,169|171,182|218,223|232,242|266,270|281,292|295,296|322,323|326,326|329,329|331,340|421,424|427,429|434,434|437,437|445,450|496,499|519,521|575,575|580,584|588,588|602,612|617,617|628,632|638,644|661,662|665,665|697,697|703,705|715,715|725,731|735,739|741,743|745,745|748,749|755,760|768,773|775,777 ????---EE------------------------------------------------EEEEEHHHHHHTHH----H-HHHHH-------------HHHH-H??------------------------------E-----------EE----------------E---EEE?HHHHHHHHHTTS-----------------------------------SSEEEE?--?----HHHHHHHHHTT-----------------------SEEEE----------EEEEEEEEEEEE?-TT------------------------?TT??T--T?SSHHHHHHHH--------------------------------------------------------------------------------HHTT??EEE--??S??H-------HHHHHH---------------------------------------------HHHH-------------------HHT?---------------------------------------------------?S?---STTEE---E--------??-??HHHHHHHHHHT----T---------?BEEEE-----HHHHHHH----------------GG--G?------------------------------S----?EEE---------E?------??GGGEEEE---EEEEE?TTT?T--TS?----HHHHHH-------HHHHHH-SHH 1IXG|A PF12850.2_Metallophos_2_seed 139 656 !Q:0,0|6,8|11,28|30,30|32,39|41,43|45,47|49,68|72,72|74,75|78,82|84,85|88,91|97,97|99,132|134,146|148,160|162,164|166,169|174,182|185,186|188,188|191,198|203,204|207,278|286,289|291,291|295,295|298,352|363,363|365,386|389,407|410,410|416,432|435,504|507,520|523,524|526,532|535,543|546,548|552,552|556,556|559,560|563,586|588,589|591,596|599,600|602,604|610,612|615,615|618,630|633,645 Q:1,5|9,10|29,29|31,31|40,40|44,44|48,48|69,71|73,73|76,77|83,83|86,87|92,96|98,98|133,133|147,147|161,161|165,165|170,173|183,184|187,187|189,190|199,202|205,206|279,285|290,290|292,294|296,297|353,362|364,364|387,388|408,409|411,415|433,434|505,506|521,522|525,525|533,534|544,545|549,551|553,555|557,558|561,562|587,587|590,590|597,598|601,601|605,609|613,614|616,617|631,632|646,655 ?EEEEE???TT-----------------?H-H--------H---H---H--------------------HHH-H--HH-----H--HS--??SEEEE?S?---------------------------?----?S-------------T-------------H---H----HHHG---------GG-?S-SE--------EEEE??TT---------------------------------------------?------------------------??HHHHHHH----H-HHH?TT------------------------------------------------------?EEESEEEEEE-T----------------------TE-------------------EE-EEEES---------??------HH----------------------------------------------------------------------HH--------------HH--H-------HH---------HS-??SEE-EEE?SS??EE------------------------E--E------ET--T---EEEEE???SS?TT-------------TS--------??---EEEEEETTTT 2DXL|A PF12854.2_PPR_1_seed 433 34 !Q:2,5|21,21 Q:0,1|6,20|22,33 SS????HHHHHHHHHHHHHHS?HHHHHHHHHHHH 4LEU|A PF12861.2_zf-Apc11_seed 5 103 !Q:0,2|18,18|20,40|44,44|46,46|50,51|55,62|68,68|71,71|85,85|88,91|95,95|98,99 Q:3,17|19,19|41,43|45,45|47,49|52,54|63,67|69,70|72,84|86,87|92,94|96,97|100,102 ---EEEEEEEEEEEEESS?S------------------???SSS?S?TTS??TTH??--????EEEET-TS?EEEHHHHHHHHTT?SB---?SSS?SB??EEE 3DPL|R PF12864.2_DUF3822_seed 46 299 !Q:0,22|31,34|40,40|43,43|49,53|68,74|78,78|90,91|97,98|106,107|109,109|118,120|133,137|147,147|171,171|174,177|192,193|197,197|203,203|210,210|232,236|238,244|261,262|266,266|273,278|281,282|294,294|296,296 Q:23,30|35,39|41,42|44,48|54,67|75,77|79,89|92,96|99,105|108,108|110,117|121,132|138,146|148,170|172,173|178,191|194,196|198,202|204,209|211,231|237,237|245,260|263,265|267,272|279,280|283,293|295,295|297,298 ?--------------------??GGGGGGSE----EEEEE?TT?EEEEE-----EETTTTEEEEEEEE???----TTS?HHHHHHHHHHH?-GGGGS??SEEEEEE??S?EEEEEGGG?-?GGGHHHHHHTTS?--??TTEEEEEEE-ETTTTEEEEEEEEHHHHHHHHHH?TT---?EEEETHHHHHHHHH--HHT-TSSSS?EEEEEE?SSEEEEEEEETTEEEEEEEEE---??S-------HHHHHHHHHHHHHHTT??TTT?EEEEEE?--?--TT--HHHHHHHHHHH?S?EE 3HRG|A PF12866.2_DUF3823_seed 28 286 !Q:0,28|36,37|44,53|57,57|65,67|69,69|71,73|75,79|85,85|91,91|96,96|105,105|108,108|112,121|125,127|130,132|137,137|140,140|143,144|147,148|154,155|178,185|198,199|203,204|212,212|214,215|221,221|225,225|229,231|234,234|237,237|246,258|261,262|273,273|276,277|280,282|285,285 Q:29,35|38,43|54,56|58,64|68,68|70,70|74,74|80,84|86,90|92,95|97,104|106,107|109,111|122,124|128,129|133,136|138,139|141,142|145,146|149,153|156,177|186,197|200,202|205,211|213,213|216,220|222,224|226,228|232,233|235,236|238,245|259,260|263,272|274,275|278,279|283,284 ??-----------------?-????-???EEEEEEE--EETTEE????-----?TTS?EEEEESS?--G-G---G?--??EEEEB?TTSEE-EEEE?SEEEEEEE?TT?SSB?---------STT???EE---EEES-SS-EE??EE??BSEEE--EEEEEEEETTEEEEEEEEEESS??-----?EEEEEEEEESSS??SSS??SSEEEEE?S--SGGGG?STT?EEE???EE?TT?HHHHHHHH-------------HT??EEEEEEEETT?SS?-EE???EE? 4IYK|A PF12867.2_DinB_2_seed 220 455 !Q:2,3|8,8|10,12|18,19|22,25|27,34|36,41|48,49|51,85|87,87|91,106|118,122|126,127|131,134|137,137|144,171|174,188|190,190|192,240|244,244|250,280|286,297|300,300|303,310|312,314|319,319|332,339|341,342|345,348|350,352|354,354|357,361|363,399|401,406|409,417|420,425|427,434|442,442 Q:0,1|4,7|9,9|13,17|20,21|26,26|35,35|42,47|50,50|86,86|88,90|107,117|123,125|128,130|135,136|138,143|172,173|189,189|191,191|241,243|245,249|281,285|298,299|301,302|311,311|315,318|320,331|340,340|343,344|349,349|353,353|355,356|362,362|400,400|407,408|418,419|426,426|435,441|443,454 HH--HHHH-H---HHHHH--HT----T?-----?-H------HHHTSB--S-----------------------------------S-TTS---------------?BHHHHHHHHHH-----HHH--HHH----HH-HHHHHH----------------------------SS---------------S?B-------------------------------------?-------????HHH-HHHSH-------------------------------HHHHS-----------?HH-HH--------H---HHHH-HHHHHHHHHHHH--?----?H--HH----H---T?EE-----E?------------------------------------T------TT-------??EE------E--------HHHHHHH-HHHHHHHHHHHH 2P1A|A PF12869.2_tRNA_anti-like_seed 25 237 !Q:0,84|92,106|111,111|121,121|131,135|137,137|153,153|157,157|166,166|169,169|171,171|173,174|182,190|199,200|211,215|218,226|229,229 Q:85,91|107,110|112,120|122,130|136,136|138,152|154,156|158,165|167,168|170,170|172,172|175,181|191,198|201,210|216,217|227,228|230,236 --------------------------------------------------------------------?????????????????HHHHHTS?--------------EEEH-HHHHHHHHH?HHHHHHHHT-----T?EEEEEEEEEEEEEEE?STT?EEEEEEEE?TT?S?S??EEEEEEG---------GGHHHHTT??TTSEEEEEEE?????SB---------SS?EEEEEEE 3F1Z|A PF12870.2_Lumazine_bd_seed 26 126 !Q:0,8|13,16|28,28|37,38|41,43|50,52|86,89|105,105|116,116|119,119|125,125 Q:9,12|17,27|29,36|39,40|44,49|53,85|90,104|106,115|117,118|120,124 ???--????HHHH----HHHHHHHHTTT?HHHHHHTB??SS??-SHHHHH---HHHHHHHHHHHHHHHHHHHTTSEEEEEEEEEEE?---SSEEEEEEEEEETTS?EEEEEEEEEE-SS-SSEEE? 3K7C|A PF12872.2_OST-HTH_seed 234 101 !Q:0,5|14,15|20,20|22,25|28,29|43,45|48,49|54,63|65,65|73,73|75,76|78,79|83,83|87,88|93,93|96,96 Q:6,13|16,19|21,21|26,27|30,42|46,47|50,53|64,64|66,72|74,74|77,77|80,82|84,86|89,92|94,95|97,100 ??????HHHHHHHH--HHTB?T----TS-?EEHHHHHHHHHHH?--TT??GGGT----------T?SSHHHHH-H--H-?TTT-EEE--EEEE?TT?SSEE 3S93|A PF12874.2_zf-met_seed 388 28 !Q:2,3|8,8|12,12 Q:0,1|4,7|9,11|13,27 TE--ETTT-TEE?SSHHHHHHHHTSHHH 2PRT|A PF12875.2_DUF3826_seed 7 188 !Q:18,18|20,20|56,59|93,94|121,121|124,125|172,173 Q:0,17|19,19|21,55|60,92|95,120|122,123|126,171|174,187 HHHHHHHHHHHHHHHHHT?S?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--??HHHHHHHHHHHHHHHHHHHHHHHTHHHHHHTTT??HHHHHHHHHHTTTTHHHHHHHHHHHH?TT??HHHHHHHHHHHHHHHHHHTTSSSHHHHHHHHHHHHHHHHHHHHHTT??HHHHHHHHHHHHHH 3G6I|A PF12876.2_Cellulase-like_seed 18 130 !Q:6,6|21,21|25,25|28,36|41,41|45,45|48,48|50,51|71,71|75,75|78,79|81,88|90,100|104,109|114,117|120,121|127,129 Q:0,5|7,20|22,24|26,27|37,40|42,44|46,47|49,49|52,70|72,74|76,77|80,80|89,89|101,103|110,113|118,119|122,126 HHHHTT?GGGEEEEESSTTTT?TTT?HH---------HHTT?TTT?TT?T--TSHHHHHHHHHHHHHHHTT?TTS?EE??B------??S----------?TTH------HHHS?--?TT?-SSEEB??? 1UZ4|A PF12883.2_DUF3828_seed 23 138 !Q:3,3|13,14|18,18|20,26|29,30|37,41|47,47|61,63|65,65|71,71|75,76|78,80|87,87|91,93|107,108|110,111|114,114|135,137 Q:0,2|4,12|15,17|19,19|27,28|31,36|42,46|48,60|64,64|66,70|72,74|77,77|81,86|88,90|94,106|109,109|112,113|115,134 HHH-HHHHHHHHH--HHT?S-------SS??GGGSGG-----GGGTB?HHHHHHHHHHHHT---T?SGGGS?TTT??S???HHHHHH?EEE???EEETTEEEEEEEE?-S--SS?EEEEEEEEEETTEEEEEEEE??? 3KZT|A PF12884.2_TORC_N_seed 13 83 !Q:0,2|29,82 Q:3,28 ???HHHHHHHHHHHHHHHHHHHHHHHHHT????-------------------------------------------------- 4HTM|A PF12888.2_Lipid_bd_seed 5 123 !Q:1,3|12,12|15,16|24,26|32,33|48,48|51,54|58,58|63,63|69,73|84,84|88,88|102,102|105,107|115,116|118,118|122,122 Q:0,0|4,11|13,14|17,23|27,31|34,47|49,50|55,57|59,62|64,68|74,83|85,87|89,101|103,104|108,114|117,117|119,121 T???SEEEEEEE?TT??SSEEEEE?--TTSSS??EEEEEEETTTTEEE?SS----SEE?SSSS?EEEEE-----EEEEEEEEEE?TTS?EEEEEEEEEEETT?TT???EEEEEEE??S?GGG? 3H3I|A PF12889.2_DUF3829_seed 47 354 !Q:19,23|41,42|45,66|74,75|77,82|85,85|97,101|113,113|123,127|132,132|173,186|190,190|204,207|214,216|221,221|223,223|227,228|236,253|268,271|274,274|276,284|307,330|337,338 Q:0,18|24,40|43,44|67,73|76,76|83,84|86,96|102,112|114,122|128,131|133,172|187,189|191,203|208,213|217,220|222,222|224,226|229,235|254,267|272,273|275,275|285,306|331,336|339,353 HHHHHHHHHHHHHHHHHHH??---HHHHHHHHHHHHHHTTS??TT?????????------------?SHHHHTS??T------TS?HHHHHHHHHHH-----HHHHHHHHHHH-HHHHHHHHH-----HHTT?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH--------------TTT?TTHHHHHHHHHHH----HHHHHH---HHHH-T?TTS??HHHHHHH------------------HHHHHHHHHHHHTS???-TT?H---------HHHHHHHHHHHHHHHHHHHHHH------------------------HTTSSS??HHHHHHHHHHHHHHT 3IEE|A PF12890.2_DHOase_seed 4 192 !Q:1,1|6,6|13,15|19,19|23,24|43,43|45,45|49,49|51,51|67,67|74,74|82,82|87,88|97,99|102,102|106,109|125,126|130,133|137,137|140,140|153,156|159,159|179,180|184,184|186,188 Q:0,0|2,5|7,12|16,18|20,22|25,42|44,44|46,48|50,50|52,66|68,73|75,81|83,86|89,96|100,101|103,105|110,124|127,129|134,136|138,139|141,152|157,158|160,178|181,183|185,185|189,191 T?EEEE?EEEEEE???TTT?TTT??HHHHHHHHHHHTEEEEEE?S?SSS?S?SHHHHHHHHHHHHHH?SSEEEE?EESBGGG?SSSB??HHHHHHTT???EE?TTS????HHHHHHHHHHHHHTT??EEE????GGG?TT?SEETTHHHHHTT--??EE?THHHHHHHHHHHHHHHHHT??EEE?S???HHH 3D6N|A PF12891.2_Glyco_hydro_44_seed 27 312 !Q:0,1|4,4|22,23|46,47|54,55|62,65|68,71|75,75|84,106|110,112|114,116|119,133|145,150|158,159|161,162|164,164|170,171|176,176|178,178|185,198|200,200|204,205|207,209|228,228|231,231|238,240|242,242|253,256|259,264|268,269|274,274|286,287|297,300|307,310 Q:2,3|5,21|24,45|48,53|56,61|66,67|72,74|76,83|107,109|113,113|117,118|134,144|151,157|160,160|163,163|165,169|172,175|177,177|179,184|199,199|201,203|206,206|210,227|229,230|232,237|241,241|243,252|257,258|265,267|270,273|275,285|288,296|301,306|311,311 ??EE?GGGTTTEEESHHHHHTT??GGGTTSTTHHHHHHHHHHHHTT??EEEEEE??SSEEES??-?EE--??GGG?SSSTTEEE-----------------------EES???S???SS??-------------TTSSEEEHHHH------HHHHHHH--H??T-TSTTS??EEEE?S?GGGHHH--------------H?TTT??S???HHHHHHHHHHHHHHHHHH?TT?EEEEEE---E?SHHHHHHTTT---?TT------HHH--HTTT?SSHHHHHHHHH--HHHHHHHTS????EEEEEE????E 3ZQ9|A PF12892.2_FctA_seed 46 134 !Q:8,10|13,15|18,19|22,28|35,35|43,43|49,49|56,58|61,61|63,63|65,66|68,71|73,73|79,79|81,88|91,93|95,99|104,105|113,119|122,123|125,126|133,133 Q:0,7|11,12|16,17|20,21|29,34|36,42|44,48|50,55|59,60|62,62|64,64|67,67|72,72|74,78|80,80|89,90|94,94|100,103|106,112|120,121|124,124|127,132 EEEEEEEE-?-SS??-TT--EE???-?-?EEEEEE-EEEETTT-TEEEE-EEEEEE---SS-S-S--B?--?E-EEEEE-E-------?EE---E-----EEEE--EEEESTT?----?-TT??E--EEEEEE? 3GLD|A PF12893.2_Lumazine_bd_2_seed 61 145 !Q:12,12|21,22|35,37|43,43|47,50|60,60|68,77|80,80|92,92|105,105|109,120|131,131|145,145 Q:0,11|13,20|23,34|38,42|44,46|51,59|61,67|78,79|81,91|93,104|106,108|121,130|132,144 HHHHHHHHHHHH-HHHHHHHT-?HHHHGGGEEEEE---EEEEE?TTS?---EEEEETHHH-HHHHHHT------????TT?EEEEEEEEEET-TEEEEEEEEEEE-TTE------------EEEEEEEEEE-ETTEEEEEEEEEE- 3BLZ|A PF12895.2_Apc3_seed 111 138 !Q:3,3|19,30|32,33|37,44|48,51|60,60|62,65|69,69|76,87|89,89|93,93|95,98|104,108|111,111|113,114|119,119|123,126|135,135 Q:0,2|4,18|31,31|34,36|45,47|52,59|61,61|66,68|70,75|88,88|90,92|94,94|99,103|109,110|112,112|115,118|120,122|127,134|136,137 HTT?HHHHHHHHHHHHHHH?----------?H--HHH--------HHH----HHHHHHTT?H----HHH-HHHHHH------------T?GGG-T?---HHHHH-----HH-H--HHHH-HTT?---HHHHHHHH?SS 3K9I|A PF12897.2_Aminotran_MocR_seed 5 430 !Q:0,5|24,25|29,34|48,49|53,53|56,56|65,65|67,67|70,71|85,85|92,92|95,95|111,112|115,115|118,118|120,121|125,128|136,137|149,149|162,162|173,173|182,182|186,186|190,194|204,206|211,211|217,217|222,222|224,226|230,235|245,245|260,260|265,265|271,271|286,286|288,290|337,337|345,347|352,352|361,361|376,378|387,388|392,392|397,398|402,402|428,429 Q:6,23|26,28|35,47|50,52|54,55|57,64|66,66|68,69|72,84|86,91|93,94|96,110|113,114|116,117|119,119|122,124|129,135|138,148|150,161|163,172|174,181|183,185|187,189|195,203|207,210|212,216|218,221|223,223|227,229|236,244|246,259|261,264|266,270|272,285|287,287|291,336|338,344|348,351|353,360|362,375|379,386|389,391|393,396|399,401|403,427 ??????HHHHHHHHHHHHHHHHHT??EES??????HHHHHTTGGGGGS??GGG?EE-TTEETTSS?S?TT??HHHHHHHHHHTTS?GGGEEE?SS?HHHHHHHHHHHHHHT??TT?SS?G--GGG--??EEEEEES??HHHHHHHHHHT?EEEEEEEETTEE?HHHHHHHHHS?TTEEEEEE?SSS?TTT?????HHHHHHHHT???SSTT?EEEEE?TTSS?B?-?SSS??????HHHHHHHHT?TTSEEEEEESTTTS?SSSS?EEEEE?HHHHHHHHHHHHHS?S???HHHHHHHHHHHHHSTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT-TTSSEEE???SBSS?EEEEESSS?HHHHHHHHHHTTEE???TTTTSSTT??SSS?EEEE??SSS?HHHHHHHHHHHHHHHHHHHHHHHTT-? 3ATH|A PF12898.2_Stc1_seed 21 114 !Q:1,2|6,7|15,15|30,32|36,36|39,43|48,55|58,77|79,79|81,81|84,85|93,93|102,107 Q:0,0|3,5|8,14|16,29|33,35|37,38|44,47|56,57|78,78|80,80|82,83|86,92|94,101|108,113 E?-SSS??EEETTTS?HHHHHTTEEEETTE---EEE?SS?????TTTS--??-???EE--------------------E?S-SS??EEESTTS?HHHHHSSS?---??HHHHTT 2LUY|A PF12900.2_Pyridox_ox_2_seed 153 213 !Q:0,0|10,10|12,12|22,25|27,30|33,34|46,48|53,53|55,60|65,65|67,76|79,79|83,101|108,111|115,122|124,134|136,136|144,144|148,153|164,170|172,180|182,198 Q:1,9|11,11|13,21|26,26|31,32|35,45|49,52|54,54|61,64|66,66|77,78|80,82|102,107|112,114|123,123|135,135|137,143|145,147|154,163|171,171|181,181|199,212 ?HHHHHHHHH-T?SEEEEEEEE----T----TE--EEEEEEEEEEE--?SSSS?E------EEEE-E??---??--?SS?TTS------------------?SEEEEE----EEE---?????E-----------E-EEEEEEE-EEE?---??HHHHHHHTTS?????-?T---------T??--------------?EEEEEEEEEEEEEE 2VPA|A PF12902.2_Ferritin-like_seed 38 370 !Q:5,5|23,23|25,25|30,62|90,113|116,117|121,121|128,128|134,134|136,137|140,142|150,150|157,158|160,202|206,212|215,217|226,226|230,241|246,248|255,256|261,290|293,294|296,303|309,312|328,359 Q:0,4|6,22|24,24|26,29|63,89|114,115|118,120|122,127|129,133|135,135|138,139|143,149|151,156|159,159|203,205|213,214|218,225|227,229|242,245|249,254|257,260|291,292|295,295|304,308|313,327|360,369 HHHHH-HHHHHHHHHHHHHHHHB-S?TTSH---------------------------------HHHHHHHHHHHHHHHHHHHHHHHHHTT??-----????--------?????TT??TTB?GGGSSS?GGGTS?S??SS???SSHHHHH-HHHHHT??G-------------------------------------------GGG???????TT???BSSHHHHH-HHH------------HHHH---HHTGGG??TTSS???----------------???????????SS??S-------?HHHHH----HHHHHHHHHHHHHHH?????????????????????-------????HHHHHHHHHH 3HL1|A PF12903.2_DUF3830_seed 13 172 !Q:14,14|29,32|37,37|40,40|53,54|56,61|64,66|68,68|74,75|95,106|108,108|116,116|120,122|130,131|144,147|160,161|164,164|171,171 Q:0,13|15,28|33,36|38,39|41,52|55,55|62,63|67,67|69,73|76,94|107,107|109,115|117,119|123,129|132,143|148,159|162,163|165,170 EEETTTTEEEEEEE?TTTSHHHHHHHHHH?--?EEEE?EE?SSSSSEEEEEEE??S------SS???S?SEESS??TTEEEEEEEEHHHHSSGGG????????????E-EEEEEEE?SSS???EETTTEE??EEEEEEEEESHH----HHHHHHHHHHHH??TT?EEEEEE? 3KOP|A PF12904.2_Collagen_bind_2_seed 12 98 !Q:2,2|9,11|16,17|22,22|25,26|32,32|36,38|48,48|70,70|72,73|79,80|83,84|89,90 Q:0,1|3,8|12,15|18,21|23,24|27,31|33,35|39,47|49,69|71,71|74,78|81,82|85,88|91,97 EE?GGGEES???SGGG??EEEE?SS--EEEEE-ESS???EEEEGGGSS?SSEEEEEEETTTTEEEEEEEE?S--SEEEE??SS?-TTSS??EEEEEEE 3KZS|A PF12905.2_Glyco_hydro_101_seed 3 457 !Q:2,3|17,19|36,37|40,41|44,44|62,62|71,71|82,82|84,84|86,86|88,88|121,121|127,128|133,133|135,135|139,139|141,141|154,154|171,174|179,179|181,182|196,197|214,214|220,220|224,224|228,228|236,236|241,241|247,249|260,260|262,262|264,267|271,271|276,277|280,286|293,295|300,301|326,328|338,338|342,343|351,351|354,355|359,359|364,364|366,366|372,373|376,376|390,393|401,401|403,403|407,407|409,410|414,414|423,423|430,431|437,437|439,440|456,456 Q:0,1|4,16|20,35|38,39|42,43|45,61|63,70|72,81|83,83|85,85|87,87|89,120|122,126|129,132|134,134|136,138|140,140|142,153|155,170|175,178|180,180|183,195|198,213|215,219|221,223|225,227|229,235|237,240|242,246|250,259|261,261|263,263|268,270|272,275|278,279|287,292|296,299|302,325|329,337|339,341|344,350|352,353|356,358|360,363|365,365|367,371|374,375|377,389|394,400|402,402|404,406|408,408|411,413|415,422|424,429|432,436|438,438|441,455 SS??SHHHHHHHHTTTS???TTGGGGGGEEEEEEEE??TT??SS?HHHHHHHHHHHHHHHTS?EEEEEEET?BTTSTTSSTT?T-T?B?GGGTHHHHHHHHHHHHHTTTEEEEEEEESSEE?TTSSS??TTTB?B?TTS?B?EEEESSSEEEEB?HHHHHHTTHHHHHHHH----HHHH?T??EEEEESTTSSTTS??SHHHHHHHHHHHHTTT?EEEES?SSS?TTT?SBBHHHH?SSSS?TTSSS???HHHHHHHTTT?B?S????GGG?GGGS??TT???????SBSGGG???SHHH--HHHHHHHHHHHHHHTTSEEEEEEE???EEEEETTEE-EEE??EEEEEEE?TT??EEE-EEES?S?TTSGG--GG?EEEEETTEEEEET----TEEEEEE?B?TTS?B??GGG?EEEEEESS?SEEEEE??HHHHT-S??EEEEEETTEEEEEEE? 2ZXQ|A PF12906.2_RINGv_seed 26 68 !Q:0,0|4,8|12,20|23,23|27,28|32,33|46,53|55,56|59,64 Q:1,3|9,11|21,22|24,26|29,31|34,45|54,54|57,58|65,67 ?SSS?????SSS--------?EE?SSS??SSS??EETTHHHHHHHH--------H??SB-----?SSS 1VYX|A PF12907.2_zf-met2_seed 13 42 !Q:0,0|11,12|15,15|26,27|29,32 Q:1,10|13,14|16,25|28,28|33,41 ?EEETTTTEEE??SS?SHHHHHHHHT??S?--?GGGTTSGGG 1WVK|A PF12909.2_DUF3832_seed 12 111 !Q:1,1|4,5|11,11|19,19|27,30|65,65|69,69|78,94|101,101 Q:0,0|2,3|6,10|12,18|20,26|31,64|66,68|70,77|95,100|102,110 T-TT??EEEEE-EEETTEE-EEEETTT?--?EEEESSHHHHHHHHHHHHHHHHHHHHHTHHHHHH-STT?GGGHHHHH-----------------HHHHSS-SHHHHHTTE 3K6Q|A PF12910.2_RelB_N_seed 97 57 !Q:0,7|29,30|33,35|39,42 Q:8,28|31,32|36,38|43,56 ?------?EEEHHHHHHTHHHHHHHHHHS??EE---EEE----TTEEEEEEEHHHHH 3D55|A PF12912.2_N_NLPC_P60_seed 25 154 !Q:0,25|27,28|32,42|44,50|57,57|59,59|67,68|70,70|73,76|79,79|100,100|103,104|106,106|115,115|118,120|122,124|126,128|130,130|136,137|149,149|153,153 Q:26,26|29,31|43,43|51,56|58,58|60,66|69,69|71,72|77,78|80,99|101,102|105,105|107,114|116,117|121,121|125,125|129,129|131,135|138,148|150,152 -----------------?????????S??SST-----------T??-----THHHHS?S?HHHHHHH--H?TT?--?SS?HHHHHHHHHHHHHHHTGGGG?SS??S?HHHHHGGG?GG---G???S---B?TTSSB??HHHHHHHHHHT?GGG? 3M1U|A PF12913.2_SH3_6_seed 53 60 !Q:0,1|4,4|14,16|24,24|27,27|35,35|39,42|49,49|51,51|53,53 Q:2,3|5,13|17,23|25,26|28,34|36,38|43,48|50,50|52,52|54,59 ??BS?TTSTTTSTT?-?TTEEEEE?TT?EEEEEEE?TTS----SEEEEE?S-S?EEEEEG 3M1U|A PF12914.2_SH3_7_seed 41 55 !Q:0,0|11,14|19,19|27,30|34,34|40,40|43,43|48,54 Q:1,10|15,18|20,26|31,33|35,39|41,42|44,47 ?HHHHHHHHSS--?-EEEE?STTEEEE---?TTS?EEEEE?TT?EEEB??????? 3M1U|A PF12916.2_DUF3834_seed 10 226 !Q:0,13|17,17|29,30|35,35|38,38|45,50|53,54|66,70|78,80|86,86|113,114|116,116|121,123|135,135|137,138|143,143|147,149|153,153|162,167|175,177|194,194|206,206|211,211|222,224 Q:14,16|18,28|31,34|36,37|39,44|51,52|55,65|71,77|81,85|87,112|115,115|117,120|124,134|136,136|139,142|144,146|150,152|154,161|168,174|178,193|195,205|207,210|212,221|225,225 ?------------?EEE?TTSGGGHHHHH--TGGG?SS?EEETTT?-????SE--EEEEGGGGGGT---??EEEEEEE???EEEEE?TTSSEEEESSTTSHHHHHHHHHHHHH--T?EEEE?-?HHHHHHHHHTT?E--EEEE-TTT???EEH-HHHHHHTT????-?EEEEESS?-?HHHHHHHHHHHHHHHH?HHHHHHHHHHH-HSSS?HHHHHHHGGG???E 3MST|A PF12917.2_HD_2_seed 3 216 !Q:0,0|15,15|19,19|22,23|26,27|52,55|74,77|79,79|83,84|108,108|121,123|152,154|208,215 Q:1,14|16,18|20,21|24,25|28,51|56,73|78,78|80,82|85,107|109,120|124,151|155,207 ?SHHHHHHHHHHGGG?BSS?SS??SS??BHHHHHHHHHHHHHHHHHHHHHTT????HHHHHHHHHHTTGGGGTS????S?SSS??HHHHHHHHHHHHHHHHHHHHHHS?GGGHHHHHHHHS???SSSHHHHHHHHHHHHHHHHHHHHHHHTT???THHHHHHHHHHHHHHTTTTSHHHHHHHHHHHHHHHTSTTGGGSSHHHHHHHHH?????-?? 2PAU|A PF12918.2_TcdB_N_seed 20 70 !Q:13,14|16,16|18,22|44,44|47,47|51,55 Q:0,12|15,15|17,17|23,43|45,46|48,50|56,69 HHHHHHHHHHHHH--H-T?????HHHHHHHHHHHHHHHHHHHHH?TT?THH-----HHHHHHHHHHHHHH 2VKH|A PF12919.2_TcdA_TcdB_seed 14 960 !Q:0,0|7,8|11,14|28,30|40,40|43,43|73,75|91,139|154,154|157,158|172,175|183,195|214,218|221,222|237,238|255,255|260,260|263,263|265,272|275,275|283,285|287,289|292,294|311,312|316,325|332,332|346,347|351,364|369,371|373,373|376,376|379,389|406,406|409,409|437,437|441,814|829,830|834,844|860,862|866,867|889,889|891,893|895,898|904,931|935,936|940,940|942,944|952,959 Q:1,6|9,10|15,27|31,39|41,42|44,72|76,90|140,153|155,156|159,171|176,182|196,213|219,220|223,236|239,254|256,259|261,262|264,264|273,274|276,282|286,286|290,291|295,310|313,315|326,331|333,345|348,350|365,368|372,372|374,375|377,378|390,405|407,408|410,436|438,440|815,828|831,833|845,859|863,865|868,888|890,890|894,894|899,903|932,934|937,939|941,941|945,951 ?SEEEEE??SS?-??HHHHHHHHHHHHH--?TTSEEEEEE?TT?TTHHHHHHHHHHHHHHHHHHHHGGGSSSS???HHHHHHHHHHHHHHH-------------------------------------------------HHHHHHHHHHHHHH?TT??HHHHHHHHHHHHS-???HHHHHHH-------------HHHHHHHHHTTTEEETTT??---TT??HHHHHHHHHHHHTS??HHHHHHHHHHHHHHHH?EEEE?TT?B?-------EE?TTSSTTS???T---TS--?HHHHHHHHHHHHHHHH??STT-------???TTGGGS?HHHHHHHHHHHHT??SGG--------------GTEE???S?EE?TT??---------EEEEETTEEEEEEEEE?TT?HHHHHHHHHHHHHHHHHHHHHHHHHHS?SSH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHHHHHHHHHHHHT??TTT-----------HHHHHHHTTGGGBTT---BTT??HHHHHTSHHHHHHHHHHHHTT?S???S????HHHHG----------------------------GGB??GGG?B???HHHHHHT???????? 2VKH|A PF12923.2_RRP7_seed 61 168 !Q:0,0|10,15|17,17|29,167 Q:1,9|16,16|18,28 ?HHHHHHTTS??---?H-HHHHHHHHHHH????---??????????---------??-?????-?????????--?????------????????????---?????????????????????--???????---????????????????????????????-????? 2MBY|A PF12924.2_APP_Cu_bd_seed 17 68 !Q:8,8|10,12|14,15|32,37|45,48|50,51|53,53|67,67 Q:0,7|9,9|13,13|16,31|38,44|49,49|52,52|54,66 SSEEEEEE?T---T??EEHHHHHHHHHHHHHT------TTEEEEE????S??S-SSEESEEEEEEEE? 2FK2|A PF12925.2_APP_E2_seed 11 217 !Q:0,10|13,13|20,20|22,22|24,31|35,44|80,80|84,90|145,145|148,149|178,179|181,182|184,187 Q:11,12|14,19|21,21|23,23|32,34|45,79|81,83|91,144|146,147|150,177|180,180|183,183|188,216 ?????????-?HH-HHHHHS?S?S--------STH----------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS?HHH-------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?SS??HHHHHHHHHHHHHHHHHHHHHHHHHHHT??S??S----SHHHHHHHHHHHHHHHHHHHHHHHHTHHH 3K66|A PF12930.2_DUF3836_seed 23 140 !Q:0,25|27,29|33,35|55,56|60,61|107,109|131,131|137,137 Q:26,26|30,32|36,54|57,59|62,106|110,130|132,136|138,139 -------------------------?T---TTT???EEEEEEETTEEEEEEEEEE??TTT??EEEEEEEEEEEETTTTEEEEEEEEEETTTTEEEEEEEEEEEEETT---EEEEEEEEEETTTTEEEEEEE-EEEEE?TT 3MSW|A PF12931.2_Sec16_C_seed 37 474 !Q:8,11|13,13|26,26|35,40|44,44|48,51|62,74|79,79|81,83|86,92|103,103|111,111|115,133|144,158|170,174|176,183|186,188|191,193|195,195|213,213|225,227|229,239|241,241|245,246|248,250|252,253|255,256|258,266|268,270|273,283|285,285|295,302|312,319|323,335|341,344|358,358|375,375|378,378|382,389|391,391|395,397|401,402|407,410|412,412|418,473 Q:0,7|12,12|14,25|27,34|41,43|45,47|52,61|75,78|80,80|84,85|93,102|104,110|112,114|134,143|159,169|175,175|184,185|189,190|194,194|196,212|214,224|228,228|240,240|242,244|247,247|251,251|254,254|257,257|267,267|271,272|284,284|286,294|303,311|320,322|336,340|345,357|359,374|376,377|379,381|390,390|392,394|398,400|403,406|411,411|413,417 HHHHHHHT----T?HHHHHHHHHHTT?HHHHHHHH------HTS?HHH----HHHHHHHHHH-???-?-????-?THHH-H---HH-------HHHHHHHTTT?HHHHHHH-HHH?------------------HHHHHHHHHS---------------HHHHHHHHHHT-----S??-?----SS--?TT???H-HHHHHHHHHHHHHHHTT?HHHHHHHHHHT---T???--------S-SSB--S---S--T--T?---?---?B???SS----------?T-TSHHHHHHH--------HHHHHHHHT--------STT--?--?--?---?GGGHH----HHHHHHHHHHHTT?HHHHHHHHHHHHHHHH-TS?TTS--------H-HHH---HHH--HHHH----H-HHHHT----?----?---?----?---?---???----??????????????????????? 3MZK|B PF12932.2_Sec16_seed 58 189 !Q:0,2|7,7|16,51|62,64|66,82|88,88|95,111|113,114|130,163|167,167|171,172|184,184|186,188 Q:3,6|8,15|52,61|65,65|83,87|89,94|112,112|115,129|164,166|168,170|173,183|185,185 ???EEEE?TTSEEEEE??????-----------------?????????????EEEEEGGGTS???H-----------------HHHHS?SSTTST-----------------T??HHHHHHHHHHHHHHH----------------------------------HHH?TTS??HHHHHHHHHHH-T??? 3MZK|B PF12933.2_FTO_NTD_seed 8 328 !Q:3,3|12,12|19,19|24,24|43,44|55,55|82,82|85,87|90,112|146,172|181,183|191,191|193,195|198,201|204,204|208,210|212,214|221,223|226,226|229,230|238,256|259,259|263,263|272,272|276,283|289,290|298,298|311,312|315,316|324,324|326,327 Q:0,2|4,11|13,18|20,23|25,42|45,54|56,81|83,84|88,89|113,145|173,180|184,190|192,192|196,197|202,203|205,207|211,211|215,220|224,225|227,228|231,237|257,258|260,262|264,271|273,275|284,288|291,297|299,310|313,314|317,323|325,325 STT-HHHHHHHH?TTEEEE?GGGS?HHHHHHHHHHHHHHHHTT??EEEEEEETTE-EEEEEEEEEEEESTTBEEEETTEEEE?EE???TT???????----------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH???????????????????????????HHHHHHHT???EEEEEEE?T---TT????EE?SSS???E---EEEEEE???SB?TT??EEEEEEE???????----????????SS?TTS?EEEEEETT?SSS-------?EEEEE??TTEEEEE?TTHHHHEEEEEE??SS?-EEEEEEE?B?? 4IE5|A PF12934.2_FTO_CTD_seed 8 199 !Q:0,0|17,18|21,21|24,36|39,41|69,69|74,76|103,103|106,106|109,117|155,155|159,163|165,175|178,178|181,181|184,184|186,187 Q:1,16|19,20|22,23|37,38|42,68|70,73|77,102|104,105|107,108|118,154|156,158|164,164|176,177|179,180|182,183|185,185|188,198 ?BHHHHHHHHHHHHTTB??SS?SS----------???BS???HHHHHHHHHHHHHHHHHTHHHHHHTTT?GGGT??-TTHHHHHHHHHHHHHHHHHHHHHHHH-HH?TT?-------?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSHHHHHS?GGG?????S--------???TT?TT?SS?S??HHHHHHHHHHH 4IE5|A PF12937.2_F-box-like_seed 369 98 !Q:3,4|13,29|31,34|36,40|42,45|48,49|51,59|63,63|65,65|67,71|82,83|85,85|87,87|90,90|96,96 Q:0,2|5,12|30,30|35,35|41,41|46,47|50,50|60,62|64,64|66,66|72,81|84,84|86,86|88,89|91,95|97,97 STT??HHHHHHHH-----------------T----T-----S-?--HH--H---------HHH-H-T-----TSSTTTHHHH--T?S-ST-TSEEE?T 3L2O|B PF12939.2_DUF3837_seed 6 106 !Q:0,0|17,22|39,43|45,45|48,48|63,67|82,86|88,90|103,103 Q:1,16|23,38|44,44|46,47|49,62|68,81|87,87|91,102|104,105 ?HHHHHHHHHHHHHHHT-?????SHHHHHHHHHHHHHHH?????T-TS?HHHHHHHHHTTGGG??--?SSHHHHHHHHHHHS??-??S???HHHHHHHHHHHT?SS 3E0Z|A PF12945.2_YcgR_2_seed 119 124 !Q:1,1|4,4|8,8|10,13|16,19|21,21|24,27|29,29|31,33|38,38|42,43|50,50|57,61|63,64|72,75|78,78|87,87|90,90|92,92|104,105|108,110|114,114|117,118|121,123 Q:0,0|2,3|5,7|9,9|14,15|20,20|22,23|28,28|30,30|34,37|39,41|44,49|51,56|62,62|65,71|76,77|79,86|88,89|91,91|93,103|106,107|111,113|115,116|119,120 S?TT?EEE-E----EE----E?TT----S?E---EEEE-EEE--EEEETT-TEEEEE??---S??HHHHHHH??--TT?EEEEEEEE?ST-T?EEEEEEEEEEE--EE--?SSS?EE--EE??? 1YLN|A PF12946.2_EGF_MSP1_1_seed 15 42 !Q:0,2|4,4|6,8|26,26|32,33|38,39 Q:3,3|5,5|9,25|27,31|34,37|40,41 ???S-S???TTEEEEEETTTEEEEEE?TTEEE--ETTE--EE 1CEJ|A PF12947.2_EGF_3_seed 174 56 !Q:4,10|18,19|21,26|28,32|41,44|54,54 Q:0,3|11,17|20,20|27,27|33,40|45,53|55,55 TTTT??--???TTEEEEE??T------T?----SSSEEEEE?---TTEEESSSS-E 1CEJ|A PF12949.2_HeH_seed 47 35 !Q:3,4|17,19|23,24|32,33 Q:0,2|5,16|20,22|25,31|34,34 STT??SHHHHHHHHHHT???SSS??SHHHHHH??S 2OUT|A PF12950.2_TaqI_C_seed 40 215 !Q:2,2|4,4|6,10|13,13|20,21|23,42|46,46|56,82|84,91|96,106|108,108|113,115|119,119|122,127|134,136|146,146|151,168|170,170|185,185|193,197|204,205|212,212 Q:0,1|3,3|5,5|11,12|14,19|22,22|43,45|47,55|83,83|92,95|107,107|109,112|116,118|120,121|128,133|137,145|147,150|169,169|171,184|186,192|198,203|206,211|213,214 EE?B?G-----GG-EETTEE??S------------------??SSS?EEEGGGGGG---------------------------T-------?GGGG-----------S?EEEE--?SSS?SS??----EEEETT???BSSSEEEEE?TTEE------------------E?HHHHHHHHTSHHHH-HHHHHHH-----TTSSSS??HHHHTT?EE 2JG3|A PF12956.2_DUF3845_seed 3 245 !Q:0,24|26,30|32,32|36,36|40,44|47,47|55,55|58,58|66,67|70,72|82,83|88,88|92,94|99,100|105,105|111,114|118,120|124,126|129,130|143,144|163,163|169,169|179,179|186,186|204,205|222,222|230,230|233,233|240,245 Q:25,25|31,31|33,35|37,39|45,46|48,54|56,57|59,65|68,69|73,81|84,87|89,91|95,98|101,104|106,110|115,117|121,123|127,128|131,142|145,162|164,168|170,178|180,185|187,203|206,221|223,229|231,232|234,239 ---------------------????B?????S?EEE?SBS?????TT?EEEEEEE?SS?EEEEEEE??TT???SSEEEEEEE??BSEE?TTS???TTBS??EEEE?SBTTB????GGG???SEE???TT??EEEEEEEEEEEE??SSSEEEEEEEEEEESSSS?SSGGG?TTEEEEEEG-GGTEEE?TTSSEEEEEEEEEEEEE??SEEEEEEEEEEEESSS?EEEEEEE?TT?EEEEEE?????- 3GF6|A PF12961.2_DUF3850_seed 10 79 !Q:17,18|24,25|27,29|32,32|43,44|60,64|67,69 Q:0,16|19,23|26,26|30,31|33,42|45,59|65,66|70,78 EEEEEEHHHHHHHHTTS??EEEEE??S???TT?EEEEEEEETT--EEEEEEEEEEEEEEE?----TT?-?TTEEEEEEE 3IUW|A PF12967.2_DUF3855_seed 2 158 !Q:0,5|15,17|33,40|54,54|57,60|68,70|72,73|76,77|81,85|87,87|95,95|122,123|141,142|153,157 Q:6,14|18,32|41,53|55,56|61,67|71,71|74,75|78,80|86,86|88,94|96,121|124,140|143,152 ??????EEEEEEETT???HHHHHHHHHHHHHHS????????SSEEEEEEEEEEE?TT????SEEEEEE???S??TT??SSS?????S?EEEEEEE?EEETTEEEEEETTEEEEEEEGGGSTT??HHHHHHHHHHHHHHHHT??GGGEEEEEEE????? 1O22|A PF12968.2_DUF3856_seed 10 144 !Q:0,0|23,23|42,42|46,48|69,69|88,89|114,114|132,133|135,136 Q:1,22|24,41|43,45|49,68|70,87|90,113|115,131|134,134|137,143 ?HHHHHHHHHHHHHHHHHHHHHT?HHHHHHHHHHHHHHHTTS?TTS???HHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHH??TTSTHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHH??S??TTHHHHH 2HR2|A PF12969.2_DUF3857_seed 94 230 !Q:2,3|7,7|11,11|20,20|35,36|39,42|48,49|59,59|63,65|69,70|73,74|76,76|81,82|88,88|94,94|99,99|102,103|105,106|109,110|119,133|136,136|138,139|142,142|145,145|151,153|156,168|183,184|190,193|195,199|208,208|212,214|222,228 Q:0,1|4,6|8,10|12,19|21,34|37,38|43,47|50,58|60,62|66,68|71,72|75,75|77,80|83,87|89,93|95,98|100,101|104,104|107,108|111,118|134,135|137,137|140,141|143,144|146,150|154,155|169,182|185,189|194,194|200,207|209,211|215,221|229,229 EE?-TTS?EEE-EEEEEEEE?SHHHHTSGGGEEEE--EE---?TTTEE--EEEEEEEEE?TTS?--EEE??GG--G-EEEE??GGGTT?GGGTT?EEEE-EE??S??TT?-EEEEEEEE---------------EE?T--TS?SS?EEEEE???SS------------?EEEEEEEEEEETTS??EEEEE----T?????EEEEETTE-EEE---EEEEEEE-??????T 3KD4|A PF12970.2_DUF3858_seed 6 118 !Q:5,8|17,19|22,23|25,27|29,29|32,32|35,35|47,47|50,50|53,53|55,56|58,58|88,89|93,93|109,109 Q:0,4|9,16|20,21|24,24|28,28|30,31|33,34|36,46|48,49|51,52|54,54|57,57|59,87|90,92|94,108|110,117 EEEEE????SSGGGGSS--?TT??S???S?EE?SS?EEEEEEEEEEE?TT?EE?S??S?EEEEETTEEEEEEEEEETTEEEEEEEEEE??SEE?HHHHHHHHHHHHHHH?GGGGEEEE 3KD4|A PF12971.2_NAGLU_N_seed 33 118 !Q:13,13|25,27|30,32|35,35|40,41|44,50|54,57|67,69|84,91|93,94|98,99|101,111|114,117 Q:0,12|14,24|28,29|33,34|36,39|42,43|51,53|58,66|70,83|92,92|95,97|100,100|112,113 HHHHHHHHHHHHT?GGGGGGEEEEE???SS---SS?EEEE--EE------?SSS?---EEEEESSHH---HHHHHHHHHHHHHS------??B??TTT??B--???-----?SS???? 2VCB|A PF12972.2_NAGLU_C_seed 34 382 !Q:11,15|17,20|36,41|43,45|47,48|50,52|57,59|62,64|69,108|110,110|127,130|135,135|152,152|170,171|183,183|196,196|208,208|214,224|227,228|231,246|273,273|275,275|279,282|306,329|331,334|336,336|343,343|346,347|352,355|357,361|363,367|374,375 Q:0,10|16,16|21,35|42,42|46,46|49,49|53,56|60,61|65,68|109,109|111,126|131,134|136,151|153,169|172,182|184,195|197,207|209,213|225,226|229,230|247,272|274,274|276,278|283,305|330,330|335,335|337,342|344,345|348,351|356,356|362,362|368,373|376,381 HHHHHHHHHHH-----S?-??HHHHHHHHHHHHTTT???--?S???S--S???GGGS???SS???SSTT----------------------------------??????S?HHHHHHHHHHHHHTHH----HHTT?HHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHTT??HHHHHHHHHHH-HHHHHHHHHHTT?GGGBHHHHHHH-HHHSS-----------TT??HH----------------HHHHHHHHHHHHTTTSSSHHHHTTTS?T-TTT????BTHHHHTHHHHHHHHHHHHHHHH???--------------???????H----H-HHHHHH-HT??TTTT????S-----S?????HHHHHH--HHHHHS 2VCB|A PF12973.2_Cupin_7_seed 88 102 !Q:0,1|4,4|16,16|20,20|22,22|25,26|35,35|40,42|45,45|48,48|63,63|67,68|77,77|80,80|83,84|86,86|88,88|91,93 Q:2,3|5,15|17,19|21,21|23,24|27,34|36,39|43,44|46,47|49,62|64,66|69,76|78,79|81,82|85,85|87,87|89,90|94,101 ??EE?SSTTEEEEEEE-EES-S-SS?-EEEEEEEE?TTEE???EE?TT?EEEEEEEEEEEETT-EEE--ETTEEEEE?TT?EE??E-E-SS?--EEEEEEES 3D82|A PF12974.2_Phosphonate-bd_seed 178 701 !Q:3,4|6,6|8,9|17,21|30,32|37,42|44,44|46,48|50,52|57,58|70,70|74,74|79,81|84,85|90,91|93,94|96,97|100,100|102,105|107,107|114,125|128,132|135,142|144,152|154,172|177,178|184,184|186,189|191,232|235,262|264,265|268,270|283,283|286,286|298,310|314,316|318,318|320,337|340,358|360,367|369,369|371,386|388,388|390,391|393,395|397,400|402,404|410,410|412,412|416,416|425,441|445,456|458,469|472,473|478,496|499,499|502,503|506,520|526,536|538,548|550,560|562,562|564,564|566,566|568,568|570,580|582,582|586,586|588,588|591,594|596,600|603,606|608,611|624,627|629,660|664,664|672,675|677,679|681,685|687,689|694,696 Q:0,2|5,5|7,7|10,16|22,29|33,36|43,43|45,45|49,49|53,56|59,69|71,73|75,78|82,83|86,89|92,92|95,95|98,99|101,101|106,106|108,113|126,127|133,134|143,143|153,153|173,176|179,183|185,185|190,190|233,234|263,263|266,267|271,282|284,285|287,297|311,313|317,317|319,319|338,339|359,359|368,368|370,370|387,387|389,389|392,392|396,396|401,401|405,409|411,411|413,415|417,424|442,444|457,457|470,471|474,477|497,498|500,501|504,505|521,525|537,537|549,549|561,561|563,563|565,565|567,567|569,569|581,581|583,585|587,587|589,590|595,595|601,602|607,607|612,623|628,628|661,663|665,671|676,676|680,680|686,686|690,693|697,700 EEE??S-S-?HHHHHHH-----HHHHHHHH---HHHH------T-S---E---EEEE??SSHHHHHHHHH-TTS?SEEE??-HH--HHHH--H--H--HH-S-?--E-EEEEEE------------EE-----TT?---?---S---------S-------------------EEEE--EEEET-T-?--S--?-------------------------------?-------SH----------------------------H--HH---HHHGGGSEEEEE?TT?TTTTHHHHHHT-------------TTT---T-T-?-----------?----GG-------------------G--------S-S----------------E-E--E---E----E--?HHHHH-H-HHH-TTSSSEEE-----------------EEH------------H------------HH--HHHH-------------------HH?HH--HH---------------TTEEE-----------E-----------E-----------E-E-E-E-E-???-------E-EEE-E-TT----S?----HH----H----HHHHHHHHHHTT--?-S--------------------------------HHH-HHHHHHH----T---E-----E---EEEE??-GGGG 2O7U|A PF12975.2_DUF3859_seed 33 169 !Q:0,4|7,7|9,10|16,46|50,50|54,56|59,59|66,66|70,71|75,90|102,102|106,106|116,118|121,121|123,123|130,131|134,135|138,146|152,152 Q:5,6|8,8|11,15|47,49|51,53|57,58|60,65|67,69|72,74|91,101|103,105|107,115|119,120|122,122|124,129|132,133|136,137|147,151|153,168 ?????EE?S??EEEEE????????????-----------????????EEE?SEE???TT?EEEEEE?EES??TTS??--------------EEEEEEEEEEE?TTS?EEEEEEEEE???TT?S?EEEEEE??SG--GG???------EEEEE-EEEETTEEEEEEEEEE 3N6Y|A PF12976.2_DUF3860_seed 2 93 !Q:17,18|35,37|48,48|80,80|83,83|86,92 Q:0,16|19,34|38,47|49,79|81,82|84,85 HHHHHHHHHHHHHTSSS-?EEHHHHHHHHHTSSSS???HHHHHHHHHH?TTEEEEEEEEEEETTTEEEEEEEEEEHHHHH-HH?TT??????? 2OD5|A PF12977.2_DUF3861_seed 13 105 !Q:0,0|9,15|21,22|33,33|48,50|94,104 Q:1,8|16,20|23,32|34,47|51,93 ?EEEEEEEE-------ESSTT??EEEEEEEESS?HHHHHHHHTTTSSS?--HHHHHHHHHHHHHHHHHHHHTTTSHHHHTTHHHHHHHHHHHHT----------? 3CJL|A PF12978.2_DUF3862_seed 9 163 !Q:11,16|20,21|24,25|34,35|37,37|66,66|80,88|90,90|97,98|101,101|111,113|121,121|124,124|132,132|136,136|139,140|143,143|162,162 Q:0,10|17,19|22,23|26,33|36,36|38,65|67,79|89,89|91,96|99,100|102,110|114,120|122,123|125,131|133,135|137,138|141,142|144,161 TTHHHHHHHTT??????TTT??SS??HHHHHHHH?-S?SEEEEEEETTEEEEEEEEEETTEEEEEE-EETTEEEEEEEES????-????B?HHHHHH??TT?BHHHHHHHH???SEEEEEE?SS?EEEEEEE?SSB?SS-?TT?EEEEEEETTEEEEEEEES? 3D4E|A PF12979.2_DUF3863_seed 3 352 !Q:0,3|7,7|17,17|27,27|31,34|38,39|54,54|57,59|64,64|70,71|90,91|96,98|100,100|106,106|126,126|129,131|136,136|139,140|152,154|160,160|163,163|165,169|171,172|175,175|178,178|180,180|190,191|197,199|206,206|208,208|219,219|225,225|229,229|232,232|241,241|282,282|304,304|308,308|320,321|326,327|334,335|341,341|351,351 Q:4,6|8,16|18,26|28,30|35,37|40,53|55,56|60,63|65,69|72,89|92,95|99,99|101,105|107,125|127,128|132,135|137,138|141,151|155,159|161,162|164,164|170,170|173,174|176,177|179,179|181,189|192,196|200,205|207,207|209,218|220,224|226,228|230,231|233,240|242,281|283,303|305,307|309,319|322,325|328,333|336,340|342,350 ????STT?EEEEEEEEE?SSTTBSSSS?BSS????GGG??HHHHHHHHHHHHTT?TT???EEEE?HHHHH??SHHHHHHHHHHHHHHHHH??EEEE???S?HHHHS?HHHHHHHHHHHHHHHHHHH?TT???SEEE?SS??HHHHHHHHHHS???EEEEE?TT?B?????B??SS?SS?B?EETTEEEEE??SGGGB???EEEESS?B?HHHHTSSSBS?SSTTS?BTT?BS?STTTHHHH?HHHHHHHHHHHHHHHHTHHHHHHSSEEEEEEEETTHHHHH?HHHHHHHHHHHHHHHHHHSTT?EEE?HHHHHHHHHHH??STTS??EEEEEE??SSTTS?TTEEEEEEE? 3LM3|A PF12980.2_DUF3864_seed 3 82 !Q:12,14|25,32|37,39|41,44|48,48|51,52|58,58|60,60|65,65|76,76|80,81 Q:0,11|15,24|33,36|40,40|45,47|49,50|53,57|59,59|61,64|66,75|77,79 EEEEEEETTSTT???EEEEEEESSS????????BTTB???B????SSB?TT??SGGGS?B?GGGS?HHHHHHHHHH?GGG?? 3LM3|A PF12981.2_DUF3865_seed 3 250 !Q:15,15|19,19|23,23|27,28|34,35|69,69|91,97|111,114|117,120|137,137|139,139|168,168|171,173|179,185|192,200|210,211|215,222 Q:0,14|16,18|20,22|24,26|29,33|36,68|70,90|98,110|115,116|121,136|138,138|140,167|169,170|174,178|186,191|201,209|212,214|223,249 HHHHHHHHHHHHHHH?GGG?TTT?TTG--GGTTT??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHTTTTTTT??-----HHHHHHHHHHHHH????TT????HHHHHHHHHHHHHHTS?H-HHHHHHHHHHHHHHHHHHHHHHHHHHHH?SS???HHHHH-------HHHHHH?????????HHHHHHHTT??GGG--------HHHHHHHHHHHHHHHHHHHHHHHHHHH 3B5O|A PF12985.2_DUF3869_seed 10 127 !Q:0,21|36,37|40,40|42,52|68,68|73,74|82,84|91,91|99,100|102,102|105,105|116,116 Q:22,35|38,39|41,41|53,67|69,72|75,81|85,90|92,98|101,101|103,104|106,115|117,126 ----??-????????-??????EEEEEEEEEETTTT--EE?G-----------GGSEEEESSSSSEEE?SSSB??EEEEEEE---EETTEE-EEEEEEE??B?TT?EEEEEEEEEE?SSEEEEEEEE 3KOG|A PF12986.2_DUF3870_seed 19 99 !Q:8,10|14,14|18,18|20,20|38,40|42,43|46,51|60,60|71,72|78,78 Q:0,7|11,13|15,17|19,19|21,37|41,41|44,45|52,59|61,70|73,77|79,98 EEEEEEEE???EEE?SSB?E-EEEEEEEEEEEEEEEEE???S??HH------HHHHHHHT?SEEEEEEEEE--EEEEE?BSEEEEEEEEEEEEEEEEEE 3KOG|A PF12988.2_DUF3872_seed 21 143 !Q:0,24|27,35|40,43|46,47|50,50|60,60|63,64|67,69|75,75|78,80|88,88|91,91|95,95|98,98|100,100|109,112|115,115|124,124|127,128|130,130|140,142 Q:25,26|36,39|44,45|48,49|51,59|61,62|65,66|70,74|76,77|81,87|89,90|92,94|96,97|99,99|101,108|113,114|116,123|125,126|129,129|131,139 ---------?--------------?TT?????????EEEE????SS??TT?EEEEEEEEE?SS??SS???EEEEE?SS???EEEETTS?EE?TTS?EE?S?SEEEEEEE???-SS?EEEEEEEE?TT--S?EEEEEEEES??? 2L3B|A PF12998.2_ING_seed 79 140 !Q:30,32|50,51|53,85|88,91|136,139 Q:0,29|33,49|52,52|86,87|92,135 HHHHHHHHSGGGHHHHHHHHHHHHHHHHHH---HHHHHHHHHHHHHHHHT??S?------------------------------??HH----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??-- 4AFL|A PF13008.2_zf-Paramyx-P_seed 26 49 !Q:3,3|5,6|22,24|27,27|31,32|37,38|40,41|47,48 Q:0,2|4,4|7,21|25,26|28,30|33,36|39,39|42,46 EEE?S--TTEEEEEEEEEESSS???SS?EEE??SSSS??S??SSSTT?? 4I1S|B PF13010.1_pRN1_helical_seed 9 147 !Q:0,15|25,31|43,45|48,67|75,77|83,84|101,103|112,112|115,115|121,121|146,147 Q:16,24|32,42|46,47|68,74|78,82|85,100|104,111|113,114|116,120|122,145 ????????--??????HHHHHHHHH??--???HHHHHHHHHTS???HH--------------------HHHHHTS???TTTTT??HHHHHHHHHHHHHHTT???HHHHHHHS?TT?TTTSS?HHHHHHHHHHHHHHHHHHHHHHHT?- 3M1M|A PF13012.1_MitMem_reg_seed 148 203 !Q:0,0|5,15|17,22|30,41|46,64|66,66|93,202 Q:1,4|16,16|23,29|42,45|65,65|67,92 ?HHHH-----------H------HHHHHHH------------HHTS??--------??-??----H-HHHHHHHHHHHHHHHHHHHHHHHHHH?-----???????????????????????--???????????----?????????-????-----------??????????--???????????????---????????? 4BGR|U PF13014.1_KH_3_seed 992 66 !Q:6,8|11,11|14,14|16,18|24,24|28,31|33,33|37,50|54,54|56,56 Q:0,5|9,10|12,13|15,15|19,23|25,27|32,32|34,36|51,53|55,55|57,65 TGGGGT--?GG-GH-H---HHHHH-HHH-?-?E-EEE??------------TTS?S-SEEEEEEEE 3KRM|A PF13015.1_PRKCSH_1_seed 5 183 !Q:0,38|41,41|63,67|80,90|99,99|101,102|108,108|117,117|120,120|143,182 Q:39,40|42,62|68,79|91,98|100,100|103,107|109,116|118,119|121,142 -----------------------------------????TT?EEEEEETTEEEEEETTTEEEE-----TTEEEEEEEEEE-----------TTEEEEEE?S??TTSSS?EEEEEEEE?SS?EEEEEEESSSSEEEEEEEEGGG?--------------?------------------------ 2LVX|A PF13016.1_Gliadin_seed 28 92 !Q:0,11|17,18|21,22|36,47|53,64|74,74 Q:12,16|19,20|23,35|48,52|65,73|75,91 ?????-------BTTTB?-SS??TTHHHHHHHHTTT--------????HHHHH------------HHHHHHHTS?TTTHHHHHHHHHHHHHH 1BIP|A PF13022.1_HTH_Tnp_1_2_seed 4 156 !Q:3,3|12,12|26,28|31,40|50,51|62,62|97,101|114,115|123,125|127,155 Q:0,2|4,11|13,25|29,30|41,49|52,61|63,96|102,113|116,122|126,126 HHH-HHHHHTTS?HHHHHHHHHHHHH---HH??????????HHHHHHHHT??HHHHHHHHHH?HHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHSSS---??HHHHHHHHHHTT??EEEEEEE---E???????????????????????---?-? 2AO9|A PF13023.1_HD_3_seed 143 239 !Q:6,6|12,12|16,16|18,18|42,48|51,52|61,63|74,77|80,95|111,114|116,116|119,124|127,135|144,157|162,168|170,170|177,189|214,214|216,216|225,225|233,234 Q:0,5|7,11|13,15|17,17|19,41|49,50|53,60|64,73|78,79|96,110|115,115|117,118|125,126|136,143|158,161|169,169|171,176|190,213|215,215|217,224|226,232|235,238 GGGGGG?EEEEE?TTS-S-SEEEHHHHHHHHHHHHHHTGGGS--?----TT??HHHHHHHH---HHTTTTHHHH????TT?----?-?????----HHHHHHHHHHHHHTT----S?HH------HH---------HHHHHHHH--------------HHHH-------T?SHHHHH-------------HHHHHHHHHHHHHHHTTSTTTTTT-T?BHHHHHHH-HHHHHHH-?HHHH 4DMB|A PF13026.1_DUF3887_seed 5 110 !Q:1,2|17,19|24,25|29,29|35,35|40,41|44,45|60,60|78,80|103,103|107,107 Q:0,0|3,16|20,23|26,28|30,34|36,39|42,43|46,59|61,77|81,102|104,106|108,109 T??HHHHHHHHHHHHHH---HHTT?-HHH-HHTTB?HHHH--TT??HHHHHHHHHHHHTT?SEEEEEEEEEEEEETTE---EEEEEEEEEEETTEEEEEEEEE?TTS?EE 4HYZ|A PF13028.1_DUF3889_seed 19 100 !Q:0,11|15,15|18,26|40,40|43,43|46,48|56,56|59,60|85,85|89,90|99,99 Q:12,14|16,17|27,39|41,42|44,45|49,55|57,58|61,84|86,88|91,98 ----------??SSS?TT??----???SSTTHHHHHHHHT?TT?EE???EEEEEEE?SS?-EEEEEEEEEEETTEEEEEEEEEEE?TTT??EEEEEEEE? 2LYX|A PF13041.1_PPR_2_seed 436 92 !Q:0,10|12,15|17,19|21,21|29,29|32,33|35,35|38,40|42,46|49,49|59,60|62,62|64,66|68,76|78,78|88,88 Q:11,11|16,16|20,20|22,28|30,31|34,34|36,37|41,41|47,48|50,58|61,61|63,63|67,67|77,77|79,87|89,91 ?-----?----H----H---H-HHHHHHH-HH--H-HT-?-H-----HH-HHHHHHHHH--H-T---S-?---?-??H-HHHHHHHHH-HHT 4LEU|A PF13083.1_KH_4_seed 211 108 !Q:3,5|7,9|20,20|22,22|24,28|34,36|38,38|40,40|42,42|52,52|54,54|57,57|61,61|80,80|82,82|85,87|89,92|94,96|98,103 Q:0,2|6,6|10,19|21,21|23,23|29,33|37,37|39,39|41,41|43,51|53,53|55,56|58,60|62,79|81,81|83,84|88,88|93,93|97,97|104,107 HHH---H---HHHHHHHHHH-T-T--???EEEEE---E-E-T-TTTEEEEEE-E?HH-HHH?STTHHHHHHHHHHHHHHH-H-HH---T-?--S---S---?-?EEEE 3GKU|A PF13085.1_Fer2_3_seed 52 244 !Q:6,7|9,69|74,77|88,88|91,91|106,115|118,126|130,130|143,148|156,159|163,209|214,214|216,217|220,220|229,238 Q:0,5|8,8|70,73|78,87|89,90|92,105|116,117|127,129|131,142|149,155|160,162|210,213|215,215|218,219|221,228|239,243 EEEEEE??S-------------------------------------------------------------SSTT?-??EEEEEEEESS-SS?SBHHHHHHHHHHTT---------?TT????--???SSS?SSTTEEEETTEE------EETTTSB????SSS?----------------------------------------------EEEE?S--SS?BEEETTEE--------??HHHHH 3AE5|B PF13086.1_AAA_11_seed 118 723 !Q:1,2|10,12|18,18|21,42|48,62|64,76|79,87|90,92|103,281|286,287|305,307|311,327|330,346|350,350|352,352|355,361|364,364|372,375|384,429|431,431|435,445|455,539|543,560|577,587|594,594|605,605|614,614|616,630|632,633|644,656|658,658|667,668|671,684|690,708|711,711|715,719|721,721 Q:0,0|3,9|13,17|19,20|43,47|63,63|77,78|88,89|93,102|282,285|288,304|308,310|328,329|347,349|351,351|353,354|362,363|365,371|376,383|430,430|432,434|446,454|540,542|561,576|588,593|595,604|606,613|615,615|631,631|634,643|657,657|659,666|669,670|685,689|709,710|712,714|720,720|722,722 T??HHHHHHH---HHHHT?SS----------------------EEEEE??-------------T-------------TS--------?HH---HHHHHHHHHH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHTT??EEEEESSHHHHHHHHHH---HHH-----------------TT?---------------?EEE?S?ST-------TS?GGGGGGB----HHHHHHSS----------------------------------------------S?HHH-----------HHTHHHHHT-------------------------------------------------------------------------------------SSS??????????????????SHHHHHHHHHHHHHHH-----------HHHHHT?SEEEEEGGGG?TTSGGGGS?T---------------T??SEEEETTGGG-------------S?HHHHHHHH--TT?-------------SEEEE-------------------EE?TTS?????S?H 2GK7|A PF13087.1_AAA_12_seed 125 507 !Q:2,3|13,32|35,36|39,39|42,42|48,50|59,61|63,68|73,79|85,85|87,142|144,148|153,153|155,155|161,196|200,200|204,218|220,220|242,243|245,262|266,267|271,271|273,273|286,288|291,291|294,294|296,325|331,368|373,373|380,381|389,407|409,415|417,478|480,480|484,484|504,504 Q:0,1|4,12|33,34|37,38|40,41|43,47|51,58|62,62|69,72|80,84|86,86|143,143|149,152|154,154|156,160|197,199|201,203|219,219|221,241|244,244|263,265|268,270|272,272|274,285|289,290|292,293|295,295|326,330|369,372|374,379|382,388|408,408|416,416|479,479|481,483|485,503|505,506 TS??HHHHHHHTT-----------------???EE??EE?SS?HHHHH---HHHHHHST---T?----?EESS------?TGGGS?T--------------------------------------------------------T?????SSSS?S-EEEEE?--------------------------------???EEE?SSB---------------S?EEEHHHHHHHHHHHHHHHHHT??G------------------GGE--EEE?S?HHHHHHHHHHHH---HS?SS?H------------------------------HHHTT--------------------------------------SEEE?SGGGTT??EEEEEEE????---------------S------?S?-------------------------------------------------------?----?S-TTS?HHHHHHHHTSEEEEEEEEE?HH 2GK7|A PF13088.1_BNR_2_seed 78 657 !Q:2,4|13,30|46,46|49,61|63,67|70,70|74,111|124,126|137,139|147,163|166,171|178,181|191,197|201,202|204,208|211,211|219,220|231,231|234,260|263,264|267,268|270,272|282,292|294,296|311,320|323,326|328,359|371,384|393,394|398,409|422,427|436,437|441,444|451,472|479,491|494,531|541,545|550,557|561,562|566,570|578,632|644,647 Q:0,1|5,12|31,45|47,48|62,62|68,69|71,73|112,123|127,136|140,146|164,165|172,177|182,190|198,200|203,203|209,210|212,218|221,230|232,233|261,262|265,266|269,269|273,281|293,293|297,310|321,322|327,327|360,370|385,392|395,397|410,421|428,435|438,440|445,450|473,478|492,493|532,540|546,549|558,560|563,565|571,577|633,643|648,656 TE---EEEEEEEE?-------?????--???EEEEEEEEEEGGGTE-EE-------------E--???EE?TTS?------------------------------------?TTEEEEEEEEEE---ETTTTEEEEE---EEEEETT?---------------?SH------HHHSSS????EEEEEEESS-------TTS--S-????EE?HHHHHGG--GGGGEEEEEE?SS??-------------------------EE??ST--T?-?EEEEEEEEE??---??????E---EEEEEEEESSTTSS---------?EE????S--------------------------------BSEEEEEEEEE????--------??EEEEEEEE--SSS------------EEEEEEESSTTS??--??EEEEEEEE??TTT????EEEEEE???----?----??----????EEEEEE-------------EE??------------------------------------SSSSEEEEE-----EEES--------STT?-GGG??-??EEEEEEE-------------------------------------------------------EEEEEEEEEEE---?TTSSEEEEE 2SLI|A PF13089.1_PP_kinase_N_seed 174 143 !Q:2,3|21,22|24,24|26,26|28,28|57,71|80,83|85,100|105,105|127,127|134,134|138,138|142,142 Q:0,1|4,20|23,23|25,25|27,27|29,56|72,79|84,84|101,104|106,126|128,133|135,137|139,141 SB??HHHHHHHHHHHHHHHHH?-T-T-S?HHHHHHHHHHHHHHHHHHHHTHHHHHHH---------------HHHHHHHH??-?S?---------------HHHH-HHHHHHHHHHHHHHHHHHHHH-HHHHHH-TTT?EEE? 1XDP|A PF13090.1_PP_kinase_C_seed 174 411 !Q:8,8|10,10|19,19|26,26|34,34|47,49|52,52|66,66|73,73|76,76|95,95|100,101|104,104|107,108|117,118|122,122|124,128|139,139|141,141|156,157|172,172|174,174|176,178|181,190|193,193|219,223|230,230|232,233|248,249|257,257|259,259|261,261|264,264|277,277|283,285|290,290|292,292|294,304|306,315|317,317|324,325|341,342|354,354|361,362|368,369|372,375|377,381|383,392|394,398|408,409 Q:0,7|9,9|11,18|20,25|27,33|35,46|50,51|53,65|67,72|74,75|77,94|96,99|102,103|105,106|109,116|119,121|123,123|129,138|140,140|142,155|158,171|173,173|175,175|179,180|191,192|194,218|224,229|231,231|234,247|250,256|258,258|260,260|262,263|265,276|278,282|286,289|291,291|293,293|305,305|316,316|318,323|326,340|343,353|355,360|363,367|370,371|376,376|382,382|393,393|399,407|410,410 SHHHHHHH-S?EEEEETTB?THHHHH-HHHHHHH?TTEEEEEEEESS??-TT?HHHHHHHHHHHTT?EEEEEE?TT?SSTTTTTTTTTHHHHHHT?EEEE??TT?EE??EEEEEEEE--ETT-E-----EEEEEEEESS?S?TTGGGTEEEEEEEE??HHHHHHHHHHHHHH-H?T---TS??------??SS?EEETTSHHHHHHHHHHHHHHHHHTT?-???EEEEES?B??HHHHHHHHHHHHTT??EEEEESS?B?B?TT?TTTSTTEEEEEE?SSSEE???EEEE?G-G-----------G----------S?EEEEES??BSHHHHHSEEEEEEE??SHHHHHHHHHH-HHHHHT??SSEEE??TT????B???-?S----------S???-?HHHHHHHHH--H 1XDP|A PF13091.1_PLDc_2_seed 205 320 !Q:7,10|12,13|19,19|21,21|23,40|43,47|49,52|57,57|60,60|66,67|73,74|79,127|132,133|138,138|143,154|157,164|166,197|199,199|205,205|207,214|226,237|239,239|242,242|244,245|247,275|277,283|287,289|291,298|307,308|311,313|317,318 Q:0,6|11,11|14,18|20,20|22,22|41,42|48,48|53,56|58,59|61,65|68,72|75,78|128,131|134,137|139,142|155,156|165,165|198,198|200,204|206,206|215,225|238,238|240,241|243,243|246,246|276,276|284,286|290,290|299,306|309,310|314,316|319,319 HHHHHHH---?S--SEEEE-E?S--??-----------?-?HH-----H----HHHH-HH-HHHHT-?EEEEE??GGGS-------------------------------------------------SSTT??HHHH-HTTT??----------EE--------E????-----------------------?--??S?EEEEE-S-------?HHHHHHHHHHH??????????--E-EE-E--E?????????---------????------?S?------EEE?-?H--------HHHHHHHH--HH---HHH--H 3HSI|A PF13098.1_Thioredoxin_2_seed 144 377 !Q:1,8|10,12|14,16|19,19|25,25|27,27|30,31|33,34|39,40|43,43|49,50|53,55|60,65|67,86|89,89|91,92|96,96|100,115|118,136|138,142|144,148|150,152|156,161|163,171|174,194|197,197|199,209|215,220|224,246|248,289|292,293|297,297|299,310|312,312|319,319|321,322|324,324|326,345|348,349|352,355|357,358|360,365|367,367|369,369|373,373 Q:0,0|9,9|13,13|17,18|20,24|26,26|28,29|32,32|35,38|41,42|44,48|51,52|56,59|66,66|87,88|90,90|93,95|97,99|116,117|137,137|143,143|149,149|153,155|162,162|172,173|195,196|198,198|210,214|221,223|247,247|290,291|294,296|298,298|311,311|313,318|320,320|323,323|325,325|346,347|350,351|356,356|359,359|366,366|368,368|370,372|374,376 E--?--?--T---T---SE-EEEEE-E?TT-?H--HHHH--HH-HHHHH?-HH---HHHH------H--------------------HH-H--EEE-EEE----------------ET-------------------T-----S??---E---EEE------E---------EE?--------------------SS?E-----------EEEEE------EHH-----------------------H------------------------------------------HH--HHT-T----------??S-SSEEEE-E?-T-T--------?--------?--EE--EE----E?-S-??-?-H-H-HHH-HHH 4AJ8|A PF13103.1_TonB_2_seed 102 113 !Q:2,2|14,16|18,28|31,32|38,39|49,49|51,51|54,55|57,57|59,59|68,69|82,85|87,90|93,96|104,107 Q:0,1|3,13|17,17|29,30|33,37|40,48|50,50|52,53|56,56|58,58|60,67|70,81|86,86|91,92|97,103|108,112 SS?HHHHHHHHHHH---T??--?---?--HH--HHHTS??EEEEEEEEE?T-TS?-E-E-EEEEEEES??SHHHHHHHHHHH----H????SS??--GGGSTTS---?EEEEE 1TOL|A PF13144.1_SAF_2_seed 119 305 !Q:7,10|16,18|23,30|33,41|44,44|49,49|51,56|60,61|63,63|65,68|70,73|76,77|79,83|85,85|90,92|95,95|100,100|105,108|110,113|115,127|130,132|135,140|150,153|155,158|163,174|177,177|179,179|181,181|184,184|186,187|202,202|205,205|207,213|216,217|219,220|229,229|231,231|234,234|236,236|244,245|248,248|251,251|260,260|272,272|274,274|276,276|286,286|290,290|297,297|301,301 Q:0,6|11,15|19,22|31,32|42,43|45,48|50,50|57,59|62,62|64,64|69,69|74,75|78,78|84,84|86,89|93,94|96,99|101,104|109,109|114,114|128,129|133,134|141,149|154,154|159,162|175,176|178,178|180,180|182,183|185,185|188,201|203,204|206,206|214,215|218,218|221,228|230,230|232,233|235,235|237,243|246,247|249,250|252,259|261,271|273,273|275,275|277,285|287,289|291,296|298,300|302,304 HHHHHHH----HHHHH---TTTT--------EE---------EE-EEEE?S----?-TTS--S?S----S----SS-?E-----E-EESS---SS?SSBS?EEEE----E----E-------------TT---EE------EEEEEEEEE----E----EEEE------------EE?S?B?TT?B??TTTEEEEEEEGGGS?TT-B??--?--TT--T--TTTEEESS?B?TT?B?BTTSEEE??SB?TT?EEEEEEEE-TTEEEEEEEEE?S?B?TTSEEEEEE-TTS?EEEEEE?TTS?EEE 3VJP|A PF13145.1_Rotamase_2_seed 206 338 !Q:0,5|7,8|17,20|22,23|27,28|31,34|36,36|38,40|42,43|46,46|48,48|51,59|63,63|66,68|71,74|77,77|79,81|83,84|87,91|95,97|100,101|103,104|106,114|117,118|122,122|124,125|128,129|131,131|134,135|137,138|140,144|154,155|158,168|171,172|175,195|197,199|201,201|203,236|238,238|244,245|247,249|252,257|259,260|262,263|265,268|270,273|276,278|280,286|289,290|293,298|300,300|302,303|312,312|314,318|320,320|322,324|327,328|330,331|333,334|336,336 Q:6,6|9,16|21,21|24,26|29,30|35,35|37,37|41,41|44,45|47,47|49,50|60,62|64,65|69,70|75,76|78,78|82,82|85,86|92,94|98,99|102,102|105,105|115,116|119,121|123,123|126,127|130,130|132,133|136,136|139,139|145,153|156,157|169,170|173,174|196,196|200,200|202,202|237,237|239,243|246,246|250,251|258,258|261,261|264,264|269,269|274,275|279,279|287,288|291,292|299,299|301,301|304,311|313,313|319,319|321,321|325,326|329,329|332,332|335,335|337,337 ?----?H--HHHHHHHH----H--HGG--GS----E-E?-?E--EE-E-EE---------EEE-SS---HH----HH-H---H--HH-----HHH---TT??H--H---------HH--HHH-H--HH--H-HH--H--H--???TTTGGGTTE--EE-----------EE?-SS---------------------S---S?H----------------------------------H-HHHHH--H---HS-----?T--T--E----E-?--SS?--E-------EE--TT------E-E--EEEEEEEE-E-?--?E-E??-HH--H--H--H-H 1ZK6|A PF13147.1_Amidohydro_4_seed 111 533 !Q:1,1|3,5|7,8|12,13|15,15|22,47|51,51|55,56|75,86|88,88|92,92|94,94|101,109|119,119|123,140|144,144|152,152|157,158|167,169|172,172|176,210|220,222|229,230|234,237|241,248|251,251|264,285|288,288|308,309|313,313|315,317|324,334|343,344|348,348|350,350|356,357|361,362|365,381|385,386|389,409|424,426|429,430|432,434|436,439|446,446|451,451|453,464|483,483|485,486|488,491|507,516|518,518|520,524|529,530 Q:0,0|2,2|6,6|9,11|14,14|16,21|48,50|52,54|57,74|87,87|89,91|93,93|95,100|110,118|120,122|141,143|145,151|153,156|159,166|170,171|173,175|211,219|223,228|231,233|238,240|249,250|252,263|286,287|289,307|310,312|314,314|318,323|335,342|345,347|349,349|351,355|358,360|363,364|382,384|387,388|410,423|427,428|431,431|435,435|440,445|447,450|452,452|465,482|484,484|487,487|492,506|517,517|519,519|525,528|531,532 E?T---T-?EEE--E?EEEEEE?-----------------------??TTT?TTT??HHHHHHHHHHHTEEEEEE-----------?S?SSS?S?SHHHHH---------HHHHHHHHH?SSE------------------EEE?EESBGGG?SSSB??HHHHHHTT???EE?TTS?-------------------------------???HHHHHHHHH---HHHHTT??EEE????GGG-------?TT?SEETTHHHHHTT--------------------??EE?THHHHHHHHHHHHHHHHHT??EEE?S???HHHHHH-----------HHHHHHTT??EEE?B?HHHHH??GGG??SS----------------?GGG??SS???-----------------?HHHHHHHHHHHHHT---SS??B???B????TTGGGS?TTTS?S?--------???TTTHHHHHHHHTTTTTSS?H--H----HHHHTTTHHHHHHHT---------?S?S??--?TTSB??EE 3O7U|A PF13149.1_DUF3988_seed 252 655 !Q:0,38|42,53|55,55|59,98|101,101|104,108|112,119|124,152|158,158|167,170|174,188|190,190|193,193|196,199|201,208|211,214|218,218|221,224|227,232|234,244|247,247|257,259|261,262|269,319|328,332|334,334|338,338|342,368|377,377|384,386|390,391|398,398|401,404|410,411|413,429|434,438|441,444|446,446|448,449|452,484|489,492|501,510|514,538|541,542|545,554|564,569|584,584|588,607|616,624|631,641|652,654 Q:39,41|54,54|56,58|99,100|102,103|109,111|120,123|153,157|159,166|171,173|189,189|191,192|194,195|200,200|209,210|215,217|219,220|225,226|233,233|245,246|248,256|260,260|263,268|320,327|333,333|335,337|339,341|369,376|378,383|387,389|392,397|399,400|405,409|412,412|430,433|439,440|445,445|447,447|450,451|485,488|493,500|511,513|539,540|543,544|555,563|570,583|585,587|608,615|625,630|642,651 --------??----------------------???-???SSS?----------?B?EEE----------------????????????------------SS?TT----?EEE--------EEEE-----------------------------ETTEE?SSSSEEEE????STT?--------------B?EE?TT?-??B?------?TT-???EEE-EE----EE------S---------??SS?BTTTEEEEE--?S??SSGGGT---------------------------------------------??----EEEEEEEE-----E?TTS?EEE??-------------------------EEESSEEE-EEEEEE?--SSS??GGGGTT?EE----EEEEE??E-----------------EEEE-----TT----T?S??EE??----------------------------???EEEE?---EEETTEEE----------EEE?--?---------------------BS??TT---------?EEEEEEGGG------TTEEEEEEGGGSTT?SSB?-------------------TTEEEEEE---------EEEETT-----------EEEEEEEEEE??? 4K4K|A PF13155.1_Toprim_2_seed 328 183 !Q:2,2|14,17|20,21|23,41|50,51|53,60|67,68|72,74|77,88|93,94|97,107|119,120|128,147|153,155|158,168|171,179 Q:0,1|3,13|18,19|22,22|42,49|52,52|61,66|69,71|75,76|89,92|95,96|108,118|121,127|148,152|156,157|169,170|180,182 EE?SSHHHHHHHHH----TT??S-------------------EEEESSSS??H--------HHHHHH--HTT--?SE------------EEEE??SS-----------HHHHHHHHHHH--HHHHHTT-------------------?EEEEE???TT-?-----?---HH---------HHH 1NUI|A PF13164.1_DUF4002_seed 26 100 !Q:1,9|21,28|34,34|37,40|44,44|46,46|51,51|57,59|62,62|64,64|68,70|76,76|81,85|87,87 Q:0,0|10,20|29,33|35,36|41,43|45,45|47,50|52,56|60,61|63,63|65,67|71,75|77,80|86,86|88,99 B?------??EEEEEEEESSS?-------GGGGT?EE?---TTS?E-EEEE?TTSSB?-?SS-S?BSS???TTSBS?TTSB?---?S?THHHHHHHTGGG 3ZZO|A PF13173.1_AAA_14_seed 476 269 !Q:1,1|8,9|18,20|22,22|26,26|32,35|39,39|46,46|48,48|52,55|57,57|59,62|69,73|77,80|83,91|93,95|98,105|108,109|115,115|117,120|122,122|128,135|138,138|141,142|152,165|175,175|177,177|188,194|196,198|201,202|204,207|220,221|224,224|227,232|235,235|242,244|246,254|256,256|259,263 Q:0,0|2,7|10,17|21,21|23,25|27,31|36,38|40,45|47,47|49,51|56,56|58,58|63,68|74,76|81,82|92,92|96,97|106,107|110,114|116,116|121,121|123,127|136,137|139,140|143,151|166,174|176,176|178,187|195,195|199,200|203,203|208,219|222,223|225,226|233,234|236,241|245,245|255,255|257,258|264,268 H?SEEEEE??TTSSHHHH---H-HHH-HHHSS----EEE-EEHHHH-H-HTT----T?B---?HHHHHT?????GGG----TS-----?---G---GG?------?HH--HHHHH-H----H-HHHHH--------HS?EE--EEEETGGGG--------------GGBTTTTTH-H-HHHHHHHHHH-------H?--TT--E----EEEEEESSHHHH--HH-HH?-----TT?TSTTTT???E---------E-EE?????HHHHH 1SXJ|B PF13174.1_TPR_6_seed 402 51 !Q:3,3|8,8|13,13|15,15|17,19|23,24|26,26|30,31|36,37|46,47|50,50 Q:0,2|4,7|9,12|14,14|16,16|20,22|25,25|27,29|32,35|38,45|48,49 HHH-HHHH-HHHH-H-H???TTS??H-HHH--HHHH--HHHHHHHH-?TT? 3KD7|A PF13175.1_AAA_15_seed 19 652 !Q:0,2|12,12|14,44|46,48|50,59|63,70|74,79|88,186|192,217|219,221|229,230|232,232|237,240|248,249|259,268|274,316|326,326|340,350|382,405|417,420|440,440|447,455|476,495|499,500|505,506|515,515|517,518|520,527|531,535|539,539|547,547|567,568|570,581|592,592|606,606|609,618|621,623|626,642|645,645|647,647 Q:3,11|13,13|45,45|49,49|60,62|71,73|80,87|187,191|218,218|222,228|231,231|233,236|241,247|250,258|269,273|317,325|327,339|351,381|406,416|421,439|441,446|456,475|496,498|501,504|507,514|516,516|519,519|528,530|536,538|540,546|548,566|569,569|582,591|593,605|607,608|619,620|624,625|643,644|646,646|648,651 ???EEEESSSSB?S??----------------------------?B???S----------SEE--------EEE??????TTHHHHHH---------------------------------------------------------------------------------------------------HHHHT??????????????????????????S???SEEEEEE??B?EESS????EEETTEE??SHHHHGGGT-?????????EEEEH-------------------------------------------HHHHHHHHS?HHHHHHHHHHHTT----------?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT????????????????????????HHHHHHHHHHH----HHHHHHHHHHHHHHHHHHH-HHHHHH---------HHHHHHHHHHHHHHHHHHHH--------------------HHS??EEEE??BSSSSGGG?B??E--------EEE----?SSS?SEESSSS?TTHHHHHHHHHHHHHHHHS??S-----------?EEEESTTTTS?THHHHHHHHHHHH?SS----------SS--?EE-----------------EE?S?HHHH 3ZGX|A PF13176.1_TPR_7_seed 162 56 !Q:2,2|9,9|13,15|18,18|29,37|41,48|50,50|53,53 Q:0,1|3,8|10,12|16,17|19,28|38,40|49,49|51,52|54,55 HH-HHHHHH-HHH---HT?HHHHHHHHHH---------HHH--------H?TT?HH 3KD7|A PF13177.1_DNA_pol3_delta2_seed 82 363 !Q:1,1|16,21|23,25|28,28|31,31|48,48|51,51|54,54|56,56|59,74|76,76|82,82|87,111|113,114|121,131|134,134|136,270|275,276|281,281|287,289|291,291|294,294|297,299|309,310|324,326|329,330|337,337|342,346|358,362 Q:0,0|2,15|22,22|26,27|29,30|32,47|49,50|52,53|55,55|57,58|75,75|77,81|83,86|112,112|115,120|132,133|135,135|271,274|277,280|282,286|290,290|292,293|295,296|300,308|311,323|327,328|331,336|338,341|347,357 S?HHHHHHHHHHHHTT---???S?--EE-EE?STTSSHHHHHHHHHHH-HS?TT?S?SS--------------??S?SHHHH-HHHH-------------------------T??TTEEEE-----------ES-S?--------------------------------------------------------------------------------------------------------------------------------------STTT--THHH-HHHHT???S?SS-SS-??EEEEETGGG??HHHHHHHHHHHHS??-TT??EEEEES?TTSS----?HHHHHTSEEEE????? 1XXH|B PF13180.1_PDZ_2_seed 52 144 !Q:0,4|13,13|19,19|24,24|28,28|30,30|36,44|54,55|57,57|59,72|74,74|84,89|91,97|102,107|112,112|118,118|127,132|143,143 Q:5,12|14,18|20,23|25,27|29,29|31,35|45,53|56,56|58,58|73,73|75,83|90,90|98,101|108,111|113,117|119,126|133,142 ?????EEEESSSS?HHHHH-HHSS?SSS?S?EEEEE--------?STTSGGGTT--S?S--------------S?EEEEETTEE?---??H-------HHHH------HHHH-HSSTT?EEEEEEEE------TTEEEEEEEE? 1N99|A PF13181.1_TPR_8_seed 158 54 !Q:1,5|8,12|15,15|21,21|25,25|28,28|30,31|34,36|48,48|50,51|53,53 Q:0,0|6,7|13,14|16,20|22,24|26,27|29,29|32,33|37,47|49,49|52,52 H-----HH-----HH-HHHHH-HHH-TT?H--HH---HHHHHHHHHHH?T--T? 2FI7|A PF13183.1_Fer4_8_seed 344 331 !Q:1,1|4,6|8,15|19,26|29,34|36,48|52,53|59,61|63,113|118,150|155,155|159,160|163,165|167,168|170,174|177,177|180,234|237,237|243,297|300,307|309,313|316,317|320,320|322,322|324,330 Q:0,0|2,3|7,7|16,18|27,28|35,35|49,51|54,58|62,62|114,117|151,154|156,158|161,162|166,166|169,169|175,176|178,179|235,236|238,242|298,299|308,308|314,315|318,319|321,321|323,323 T-TT---T????-?--TTG--------GG-----?H-------------HHH--HHTTT???H---------------------------------------------------HHHH---------------------------------HHHH-HHT-?TT???H--H-----HH-HH-------------------------------------------------------TT?STTTT-------------------------------------------------------TT?---????H-----HH--HH?T-T-----?? 3AE5|B PF13184.1_KH_5_seed 54 93 !Q:13,16|20,20|27,27|42,55|57,57|64,65|68,73|86,88|92,92 Q:0,12|17,19|21,26|28,41|56,56|58,63|66,67|74,85|89,91 TTTEEEEEEEESS----TTS?HHHHHH?GGGHHHHHHHHHTT--------------T?EEEEEE??SS------HHHHHHHHSTTS???EEE? 1K0R|A PF13185.1_GAF_2_seed 408 302 !Q:0,0|3,5|7,7|14,16|18,21|23,23|25,26|29,29|32,38|42,43|48,48|51,57|60,61|66,83|91,96|101,104|107,109|114,114|116,132|142,157|165,165|168,181|191,208|212,221|224,225|229,229|233,235|237,237|243,243|245,248|252,255|258,279|281,281|283,284 Q:1,2|6,6|8,13|17,17|22,22|24,24|27,28|30,31|39,41|44,47|49,50|58,59|62,65|84,90|97,100|105,106|110,113|115,115|133,141|158,164|166,167|182,190|209,211|222,223|226,228|230,232|236,236|238,242|244,244|249,251|256,257|280,280|282,282|285,301 ?SS---H-HHHHHH---H----H-H--HH-HH-------HHT-?SEEE-EE-------EE--ETTT------------------TEEEEEE------EESS?---GG---GTTT?E-----------------EETTSHHHH----------------HHHHHTS?EE--------------ESSGGGSTT??-?---?-?????????EEE----------EE--EEE-ETT---E-EEEEE-E----EEE----SS?-----------------????H-H--HHHHHHHHHHHHHHHHH 3KO6|A PF13186.1_SPASM_seed 441 215 !Q:0,9|12,14|20,23|25,34|42,64|67,69|72,72|75,84|87,87|89,91|93,94|96,101|103,108|112,118|120,123|125,125|128,133|138,140|143,147|155,180|184,184|188,195|197,198|200,214 Q:10,11|15,19|24,24|35,41|65,66|70,71|73,74|85,86|88,88|92,92|95,95|102,102|109,111|119,119|124,124|126,127|134,137|141,142|148,154|181,183|185,187|196,196|199,199 ?--------?HH---HHEEE----E?---------TTSEEES----?------------------TT?--TT?TT--------??EE-T---T--T------S----?-HHH-------H----H-TS------HHHH---HH-----HHHHHTT-------------------------?GGG?TTT--------T--T-------------?? 4K39|A PF13187.1_Fer4_9_seed 188 157 !Q:1,16|18,22|24,25|29,39|42,45|56,113|115,116|124,139|141,143|147,147|150,150|153,153|155,155 Q:0,0|17,17|23,23|26,28|40,41|46,55|114,114|117,123|140,140|144,146|148,149|151,152|154,154|156,156 G???-?------?----H-----H--HHH-?---------TT???-EEETTTTEEE------------------------------------------------------??-?T--THHHHTT----------------T???HHH-HH?TT-S?E 1ROF|A PF13188.1_PAS_8_seed 488 186 !Q:5,8|10,12|15,19|21,21|24,24|28,30|32,43|45,51|54,66|68,76|80,85|87,87|95,102|104,116|118,119|122,127|134,137|139,149|155,156|161,162|167,170|173,183 Q:0,4|9,9|13,14|20,20|22,23|25,27|31,31|44,44|52,53|67,67|77,79|86,86|88,94|103,103|117,117|120,121|128,133|138,138|150,154|157,160|163,166|171,172|184,185 HHHHH----H---HH-----H?SS-EEE---E------------E--?----TT?------------B---------EEE------E?HHHHHHH--------T-------??----G--GG------TTTSBG----G-----------GTBTT??HHHH--HHHH----HT---------??TT 2PR6|A PF13189.1_Cytidylate_kin2_seed 174 276 !Q:6,6|10,10|23,23|25,25|28,31|33,33|35,35|44,121|131,133|135,140|146,146|148,148|150,150|153,154|169,171|173,173|175,176|185,187|193,207|210,210|215,218|220,220|222,224|226,226|228,228|245,245|251,252|255,255|257,261|263,263|267,267|273,273 Q:0,5|7,9|11,22|24,24|26,27|32,32|34,34|36,43|122,130|134,134|141,145|147,147|149,149|151,152|155,168|172,172|174,174|177,184|188,192|208,209|211,214|219,219|221,221|225,225|227,227|229,244|246,250|253,254|256,256|262,262|264,266|268,272|274,275 EEEEEE?TTS?HHHHHHHHHHHH-T?EE----E?H-HHHHHHHH?-????????-????????---------???-????????????????----------------------????????HHHHHHHHH---H------HHHHH-H-H-HS-?EEEESTTHHHHHHH--?T-T??EEEEEEEE-??HHHHH---------------HH-HHHH----H-T??-H-H-HHHHHHHHHHHHHHHH-HHHHH--SS?T-----T?GGG?SEEEE?TT 3HDT|A PF13191.1_AAA_16_seed 217 521 !Q:0,1|4,4|9,13|21,22|24,24|30,48|52,52|54,54|63,68|71,78|80,81|90,104|110,112|122,128|131,131|133,144|150,150|159,282|285,287|293,319|324,333|336,336|338,366|370,370|373,421|431,444|448,450|456,464|468,468|472,473|480,517 Q:2,3|5,8|14,20|23,23|25,29|49,51|53,53|55,62|69,70|79,79|82,89|105,109|113,121|129,130|132,132|145,149|151,158|283,284|288,292|320,323|334,335|337,337|367,369|371,372|422,430|445,447|451,455|465,467|469,471|474,479|518,520 ??TT?HHHH-----HHHHHTT--G-GGTSS???--------------??EEE?B?TTSSHHHH------HH--------H--HHHHHHHH---------------HHHHT??-EEEEEEETT-------TS?S------------HHHHH-HHHHHHHS??------------------------------------------------------------------------------------------------------------------------??SS???HHHHH---------------------------HHHH----------HH-H-----------------------------TTS?SE-------------------------------------------------EEEEEETTT--------------HHH---HSTTH---------HHH-HHH--HHHGGG???---------???---------------------??EEE 3HU2|A PF13192.1_Thioredoxin_3_seed 112 105 !Q:5,6|8,10|13,13|15,15|20,22|36,36|38,40|42,45|50,53|55,56|62,63|68,68|73,73|75,75|79,82|88,88|91,94|98,98|103,104 Q:0,4|7,7|11,12|14,14|16,19|23,35|37,37|41,41|46,49|54,54|57,61|64,67|69,72|74,74|76,78|83,87|89,90|95,97|99,102 EEEEE--E--?SS-S-STTH---HHHHHHHHHHHHT-T-??E----EEEE----E-?SHHHH--HHHT?SSSS?E-EET----TEEEE?SS-???HHH-HHHH?? 3VFI|A PF13193.1_AMP-binding_C_seed 574 192 !Q:6,6|10,15|17,20|22,22|24,25|29,31|34,35|38,40|43,43|46,56|60,60|64,64|69,70|73,74|76,89|91,110|115,117|120,123|128,134|136,140|143,148|150,150|152,162|166,168|170,170|172,172|176,179|181,185|187,187|191,191 Q:0,5|7,9|16,16|21,21|23,23|26,28|32,33|36,37|41,42|44,45|57,59|61,63|65,68|71,72|75,75|90,90|111,114|118,119|124,127|135,135|141,142|149,149|151,151|163,165|169,169|171,171|173,175|180,180|186,186|188,190 HHHHHH-HTS------T----T-E--EEE---EE--EE---EE-ET-----------TTE-EEE-EEEE--EE-?T--------------T?----------------???HHHH---HH----HHHH-------H-----HH------H-T?----------GGG??-S-E-EEE?---S?--??B?SSS? 3NYQ|A PF13199.1_Glyco_hydro_66_seed 25 885 !Q:3,3|7,7|11,12|17,17|21,22|26,26|29,29|41,41|48,48|55,55|58,58|62,63|70,70|75,75|88,88|91,92|104,104|111,112|117,120|128,131|133,133|150,150|153,154|159,159|161,162|168,168|170,170|174,176|180,180|183,183|187,195|214,214|229,230|232,245|248,248|250,252|266,267|272,272|275,290|295,296|299,299|319,320|326,330|337,343|347,349|353,359|362,379|396,396|401,409|414,414|426,426|428,429|432,432|436,437|442,444|453,453|465,469|475,482|484,486|490,496|498,498|501,547|549,549|551,551|562,626|628,629|645,645|649,649|653,655|659,662|666,666|669,670|676,678|681,683|706,710|713,714|717,717|720,721|725,725|728,729|731,735|737,753|756,756|758,758|767,767|769,769|774,775|782,782|786,788|790,791|794,794|796,801|807,812|822,822|824,824|826,827|842,842|850,850|854,855|861,861|865,865|868,868 Q:0,2|4,6|8,10|13,16|18,20|23,25|27,28|30,40|42,47|49,54|56,57|59,61|64,69|71,74|76,87|89,90|93,103|105,110|113,116|121,127|132,132|134,149|151,152|155,158|160,160|163,167|169,169|171,173|177,179|181,182|184,186|196,213|215,228|231,231|246,247|249,249|253,265|268,271|273,274|291,294|297,298|300,318|321,325|331,336|344,346|350,352|360,361|380,395|397,400|410,413|415,425|427,427|430,431|433,435|438,441|445,452|454,464|470,474|483,483|487,489|497,497|499,500|548,548|550,550|552,561|627,627|630,644|646,648|650,652|656,658|663,665|667,668|671,675|679,680|684,705|711,712|715,716|718,719|722,724|726,727|730,730|736,736|754,755|757,757|759,766|768,768|770,773|776,781|783,785|789,789|792,793|795,795|802,806|813,821|823,823|825,825|828,841|843,849|851,853|856,860|862,864|866,867|869,884 EES?SSB?TTS-?EEEE?EEE??SSS?EE-EEEEEEEEETT-EEEEEE-EEEEEE?TT?EEE??TTSEEE?TTSS?SSEEEEEEEEEE?TT??EEEEEEEEEEE?SSTTSS??EEEE??--BGGGTTB----B?GGGHHHHHHHHHHHHH-TT??EEEE?S??SBTTB?S?SSS---EEE?TT?TTT------?-?EEEHHHHHHHHHHHHHHT?EEEEEEESSEEESS--S------------??SS?G---GGBEEESSSBTTB-?TTSB?EE??----????-----?EEEB?-TT?HHHHHHHHHHHHHHHHHHT??EEEEE?????EEEEGG-------GTT???GGG------?EE------------------THHHHHHHHHHHHHHS-TTSE---------EEEB?GGGTTHHHHTT-S??SS?EEE??TTSE---ETTEEEES?BHHHHHHHHHH-----HHHHH--------S???EEE???????B?TT-----------------------------------------------S?B?SHHHHHHHTT?----------------------------------------------------------------B??HHHHHHHHHHHHHTT?EEE?EEE???GGG----TTS?EE??SSSTT???SB??-HHHHHHHHHHHHHHHHTHHHHH-----SS-?EE?SS??EEE?TT??B?-???T-----------------TS?S?SSEEEEEE-E?SSEE--EEEEEE?TTS?-?B--SS?T------TGGGS??????EEEEEEEEE?S-S??HHHHHHHTTSEEEE?SSTTTTT?EEE??EEEEE?TTS?EE-EEEEEEEESSEEEEEE 3VMO|A PF13201.1_Xylanase_seed 30 513 !Q:0,12|14,19|21,22|24,29|37,37|39,49|63,64|67,67|69,70|75,75|80,81|84,84|87,94|98,100|102,107|109,113|116,117|119,133|141,154|159,159|163,166|173,176|181,187|189,190|193,195|198,209|211,213|216,217|220,220|223,223|225,227|231,231|237,239|241,241|251,253|255,255|267,268|270,270|273,273|278,278|281,281|284,284|291,293|295,296|298,300|303,304|312,312|315,315|320,320|328,328|331,332|334,336|348,349|354,357|359,359|361,361|365,371|373,377|386,386|391,403|408,411|414,415|418,420|423,424|431,432|435,436|438,452|455,455|462,463|469,472|480,480|502,502 Q:13,13|20,20|23,23|30,36|38,38|50,62|65,66|68,68|71,74|76,79|82,83|85,86|95,97|101,101|108,108|114,115|118,118|134,140|155,158|160,162|167,172|177,180|188,188|191,192|196,197|210,210|214,215|218,219|221,222|224,224|228,230|232,236|240,240|242,250|254,254|256,266|269,269|271,272|274,277|279,280|282,283|285,290|294,294|297,297|301,302|305,311|313,314|316,319|321,327|329,330|333,333|337,347|350,353|358,358|360,360|362,364|372,372|378,385|387,390|404,407|412,413|416,417|421,422|425,430|433,434|437,437|453,454|456,461|464,468|473,479|481,501|503,512 ?????????????S??----E--E------EESSEEE-E-----------EEETTTTEEEEEE--ET-T??TTSB?EEEE??TT?EE--------EES???T------T---??SS?-B------?------??STTSEEE--------------EEEE?SSS????EEEEEE----EEEE?----?-S--EE???EE???---------S---SS??EE-EE-E???SSS?EEEEE--?B?SHHHHHTTT??-S-SGGGSSEEEEE?-G-GG?EEEE-EE?EE?HHHHHH---T--T??-EE??EEESEEE?GG-GTTT?HHHHEEE?EE??S--?EEEEEEEEEEE??SSEE----E-T-TEE-?----?S?????EEEEEEEE?SSTT?----------?-EETT----TT--TT--?TT--EEEEEE??GG--G???---------?--SS?EEEEEE?-EESTT????HHHHHTT?EEEEEEEESSTTGGGTEEETT?EEEEEEEEEE 4JRL|A PF13202.1_EF-hand_5_seed 149 34 !Q:2,2|4,5|9,9|12,12|20,20|25,27|30,31 Q:0,1|3,3|6,8|10,11|13,19|21,24|28,29|32,33 HH-H--HHH-HH?SSSSSEE?HHHH---HH--HH 1YX7|A PF13204.1_DUF4038_seed 28 353 !Q:3,3|10,10|12,13|19,19|26,27|29,30|45,46|53,53|58,58|60,64|68,68|71,72|75,84|87,88|91,93|96,98|115,115|123,123|129,143|147,148|166,166|178,190|209,213|216,219|224,225|228,230|240,240|243,244|250,251|253,256|259,260|262,262|265,266|269,269|272,272|275,275|281,282|291,293|299,301|304,304|310,314|318,318|320,321|337,338|344,344|352,352 Q:0,2|4,9|11,11|14,18|20,25|28,28|31,44|47,52|54,57|59,59|65,67|69,70|73,74|85,86|89,90|94,95|99,114|116,122|124,128|144,146|149,165|167,177|191,208|214,215|220,223|226,227|231,239|241,242|245,249|252,252|257,258|261,261|263,264|267,268|270,271|273,274|276,280|283,290|294,298|302,303|305,309|315,317|319,319|322,336|339,343|345,351 TSS?EEETTS?B??EEEEE?TTHHHH??H--HHHHHHHHHHHHTT??EEEEES?SSSS?B----?TTS?BS?-SS----------TT??TT???TT???HHHHHHHHHHHHHHTT?EEEEESS?HHHHH---------------TTS??HHHHHHHHHHHHHHHTT?SSEEEEEESSS------------?TTSSHHHHHHHHHHHHHH??---SS---?EEEE??BT---EETHHHHTT?TT??SEEEE??S??--TT??S?SS??SS?TT?TT?THHHH--HHHHHSSS???EEESS???BT?BTTSS?----TTS?B??HHHHHHHHHHHHHHT?-SEEEE?BHHHHTT? 3KZS|A PF13205.1_Big_5_seed 269 242 !Q:5,5|9,10|13,16|19,22|25,27|29,31|34,34|38,51|60,61|63,66|70,70|78,78|81,91|96,96|99,99|101,104|106,106|109,123|126,126|130,130|134,135|141,154|156,159|162,163|168,168|170,174|176,176|178,184|186,190|194,196|198,208|210,226|230,237|241,241 Q:0,4|6,8|11,12|17,18|23,24|28,28|32,33|35,37|52,59|62,62|67,69|71,77|79,80|92,95|97,98|100,100|105,105|107,108|124,125|127,129|131,133|136,140|155,155|160,161|164,167|169,169|175,175|177,177|185,185|191,193|197,197|209,209|227,229|238,240 HHHHH-HHH--HS-???EE----EE---E---EE-ETT--------------EEEEEESS-?B---?TTT?SGGGEEE-EE-----------TTSS?EE?E----E-EE---------------EE?TTS-SEE--EEEES--------------S?-??TT-?EEEE-E-----E?S------?B-----BTT---S--?--------B-??---------?----EEE--------EEE? 1OT4|A PF13207.1_AAA_17_seed 412 367 !Q:5,8|21,25|28,28|30,44|46,55|57,65|67,71|73,75|77,78|83,86|88,102|106,106|111,111|115,116|119,129|131,133|136,141|143,147|150,156|161,164|168,180|189,222|233,233|237,245|247,247|251,252|256,261|268,286|290,291|293,297|299,300|305,310|314,315|317,318|323,324|326,354|356,356 Q:0,4|9,20|26,27|29,29|45,45|56,56|66,66|72,72|76,76|79,82|87,87|103,105|107,110|112,114|117,118|130,130|134,135|142,142|148,149|157,160|165,167|181,188|223,232|234,236|246,246|248,250|253,255|262,267|287,289|292,292|298,298|301,304|311,313|316,316|319,322|325,325|355,355|357,366 EEEEE-?-?TTSSHHHHHHHH-----HH-H---------------T----------T--------?E-----E---E--EHHH----H---------------HHH-HHHH-HHH--TT?---------?S---SS------S-----TT-------HHHH----HHT?-----------?EEEEEETT----------------------------------EEEEEETTEE?TTG---------G-GSH--HHH------HHHHHH-------------------TTS--H-----H--HHHH------HHH--H--HHTT??S-----------------------------S?EEEEESSIII 2BBW|A PF13229.1_Beta_helix_seed 178 436 !Q:0,0|3,6|9,9|12,12|14,31|33,37|46,68|71,71|76,76|80,101|105,105|107,113|118,126|129,129|134,134|137,159|161,161|166,166|170,173|181,202|207,207|210,212|214,215|220,220|225,233|236,249|252,253|255,255|257,257|259,276|278,282|285,288|291,291|298,313|315,316|319,324|328,330|333,354|359,359|363,374|376,376|378,401|407,407|410,410|413,428|433,433 Q:1,2|7,8|10,11|13,13|32,32|38,45|69,70|72,75|77,79|102,104|106,106|114,117|127,128|130,133|135,136|160,160|162,165|167,169|174,180|203,206|208,209|213,213|216,219|221,224|234,235|250,251|254,254|256,256|258,258|277,277|283,284|289,290|292,297|314,314|317,318|325,327|331,332|355,358|360,362|375,375|377,377|402,406|408,409|411,412|429,432|434,435 ?SE----EE?SS?E------------------E-----EESEEEES?----------------------SS?SEEE?SSS?---------------------EEE-S------?EEES--------?SS?SEEE?TT---------------------??S?EEES?EEE????TTTTTSS?--------------------?SEEE?TT-??S??EEES?EEES?--------SS?-------------SE--E?T-T----------------??S?---?EE----ES?EEESTT-------------???S??TT??????SEE???TT-----------------?????EEES?EEE------------S?S------------------------SEEEE?TT?SS--------------??EEES?EE 3VSV|A PF13230.1_GATase_4_seed 97 322 !Q:0,2|14,14|19,24|33,33|42,51|61,61|66,67|77,79|91,93|95,96|101,101|103,103|109,109|121,121|123,123|126,138|141,144|147,148|165,166|168,169|171,174|181,181|195,196|205,205|210,210|212,215|217,223|232,233|235,238|243,244|252,256|261,261|270,270|273,277|282,282|286,286|289,289|297,299|304,321 Q:3,13|15,18|25,32|34,41|52,60|62,65|68,76|80,90|94,94|97,100|102,102|104,108|110,120|122,122|124,125|139,140|145,146|149,164|167,167|170,170|175,180|182,194|197,204|206,209|211,211|216,216|224,231|234,234|239,242|245,251|257,260|262,269|271,272|278,281|283,285|287,288|290,296|300,303 ???EEEEEEEEEEE?EEEE??????SSSSSSSB?EEEEEEEE----------TTEEEEEEE?SBSS??HHHHHHHHS?-?EEEEEEEEEEE???S??SGGG?S?EEEEE-TTEEEEEEEES?B-SS--?????-----?SS?--?SS??HHHHHHHHHHHHHHHH?-S--S-???HHHHHH-HHHHHHHHHHTTB??EEEEESSS?EEEE?S----S?------EEEEEEES--S?-??EEEE-?SSEEEEE???--SSTT?EEEEEESS?SS-----SSSS?EEE?TT?EEEEETT---EEEE?--------------??? 3OOJ|A PF13234.1_rRNA_proc-arch_seed 86 418 !Q:6,6|16,40|59,67|70,78|104,110|120,122|130,141|144,145|152,156|161,207|218,220|224,225|227,231|234,234|239,252|259,260|262,280|284,284|286,286|295,300|303,303|310,311|320,328|335,338|341,345|355,358|380,380|383,385|390,391|416,417 Q:0,5|7,15|41,58|68,69|79,103|111,119|123,129|142,143|146,151|157,160|208,217|221,223|226,226|232,233|235,238|253,258|261,261|281,283|285,285|287,294|301,302|304,309|312,319|329,334|339,340|346,354|359,379|381,382|386,389|392,415 HHHHHH-SSHHHHHHH-------------------------HHHHHHHHHHHHHHHHTT???------TT---------HHHHHHHHHHHHHHHHHHHHHHHHH-------HSHHHHHHH??-TTEEEEE??----------TT??EEEEEE-----EEEE?-???-??--???--------------?-?-----------------SSSSEEEEEE???STT??S--???SS?TTTT?------------?SGGGSS??S???-?--????----????EES-S?EEEEEEEE????--TT-TTSHHH--HHHHHHHH---------HHHHHH--?-SS?---?TTHHHHHHH????HHHHHHHHHHHHHHHHHHHSS?TT?--SSHH--HHHHHHHHHHHHHHHHHHHHHHHH?? 4A4Z|A PF13237.1_Fer4_10_seed 189 171 !Q:7,24|29,33|35,42|48,48|52,53|57,64|74,74|77,79|92,92|97,162|168,169 Q:0,6|25,28|34,34|43,47|49,51|54,56|65,73|75,76|80,91|93,96|163,167|170,170 HTTGGGG?-?-----?-???-----HHHH-----H-?------HHHHH?TTS??HHH--------HHHHHHHHT?TT???THHHHHHHHSTT-TGGG-----------------------???-------------------------?------?-------HHHHH-?T 2C3M|A PF13238.1_AAA_18_seed 124 237 !Q:4,4|18,22|26,31|33,35|37,55|68,68|76,89|96,96|100,102|111,132|136,137|139,142|146,146|148,149|153,154|158,158|162,188|193,194|196,196|206,207|210,211|217,227 Q:0,3|5,17|23,25|32,32|36,36|56,67|69,75|90,95|97,99|103,110|133,135|138,138|143,145|147,147|150,152|155,157|159,161|189,192|195,195|197,205|208,209|212,216|228,236 EEEE?STTSSHHHHHHHH-----HHH------H-??E-------------------EEEHHHHHHHTT?EEEEETT--------------TTEEEE?HHH---HHHHHHHH----------------------HHH??E----EEE?S??TTS-?GGG?SEE---------------------------EEEE??H-HHHHHHHHH--TT??HHHHH-----------HHHHHHHTT 1ZMX|A PF13241.1_NAD_binding_7_seed 422 379 !Q:3,5|8,10|23,24|33,33|36,39|41,41|43,44|47,54|56,56|58,60|63,71|73,73|81,81|83,113|116,164|167,215|217,228|231,232|236,238|243,253|256,257|262,263|267,267|269,285|288,296|300,302|304,305|307,309|316,317|321,324|327,328|333,333|337,338|342,342|346,354|356,358|363,373|376,377 Q:0,2|6,7|11,22|25,32|34,35|40,40|42,42|45,46|55,55|57,57|61,62|72,72|74,80|82,82|114,115|165,166|216,216|229,230|233,235|239,242|254,255|258,261|264,266|268,268|286,287|297,299|303,303|306,306|310,315|318,320|325,326|329,332|334,336|339,341|343,345|355,355|359,362|374,375|378,378 EEE-??TT--?EEEEEEESHHHH--HHHHHHGG-GT--?-E-E--EE--------E-E---EE---------E?TTHHHHH?G-------------------------------GG????-??-------------??-----????--------?---------EE-------------------------------------------------E-----------?TT??TTS???SEEE?----------SS??GGGG??SST-T-----?----------?EE---------EEE---E??S?--HHHHHH--HHH----HH--HHHH?TTS--EEE-ETT--------?G---GGBS-----------EE??E 1KYQ|A PF13242.1_Hydrolase_like_seed 437 193 !Q:0,1|5,7|9,9|16,21|27,56|58,88|92,101|105,105|109,109|122,125|128,130|136,136|139,143|145,156|162,168|170,170|172,175|178,178|180,181|185,185|187,189|192,192 Q:2,4|8,8|10,15|22,26|57,57|89,91|102,104|106,108|110,121|126,127|131,135|137,138|144,144|157,161|169,169|171,171|176,177|179,179|182,184|186,186|190,191 ?-STT---S-THHHHH------HHHHH------------------------------T??-----------------------------GGG----------EEE-EES?TTTHHHHHHHTT--?-EE---EEESS-SS---??G------------GGGSS------?S-S--??SE-E--ESS-G---GG? 2HDO|A PF13243.1_Prenyltrans_1_seed 26 203 !Q:11,12|16,25|27,32|35,40|42,50|60,60|67,71|73,84|91,91|101,102|104,105|107,108|112,121|126,128|130,130|136,136|139,140|142,145|148,148|152,152|155,155|158,158|162,162|167,175|180,180|183,185|195,200 Q:0,10|13,15|26,26|33,34|41,41|51,59|61,66|72,72|85,90|92,100|103,103|106,106|109,111|122,125|129,129|131,135|137,138|141,141|146,147|149,151|153,154|156,157|159,161|163,166|176,179|181,182|186,194|201,202 HHHHHHHHHHH??TTS??----?--?S------SB------S--------?HHHHHHHHH-HHHHHT-----T-------??---TTSHHH-HHHHHHHHT--T??T--TSS??---??---GGGG---T?GGGTT?SS??H----HH-HHH-HH-HH-HHH-TTTT---------SSHH-HH---HHHHHHHHH----??TT 1GSZ|A PF13245.1_AAA_19_seed 209 134 !Q:8,14|17,19|25,25|29,29|32,32|43,65|70,73|78,79|88,88|91,91|96,116|118,122|124,125 Q:0,7|15,16|20,24|26,28|30,31|33,42|66,69|74,77|80,87|89,90|92,95|117,117|123,123|126,133 HHHHHHHH------?SE---EEEEE?TTS?HH-HHHHHHHHHH-----------------------HHTT??--EEEE--ESSHHHHH-HH-HHHH---------------------T-----S?-EEEHHHHT 2GK7|A PF13246.1_Hydrolase_like2_seed 225 281 !Q:3,5|7,11|13,18|21,26|28,28|31,43|48,66|70,71|81,84|89,90|93,139|143,147|150,152|156,156|161,162|164,166|170,170|173,174|178,200|202,207|209,209|211,211|213,247|250,254|256,257|260,260|265,265|273,275|278,278 Q:0,2|6,6|12,12|19,20|27,27|29,30|44,47|67,69|72,80|85,88|91,92|140,142|148,149|153,155|157,160|163,163|167,169|171,172|175,177|201,201|208,208|210,210|212,212|248,249|255,255|258,259|261,264|266,272|276,277|279,280 HHS???E-----E--?---SS-----?T-TS------------?GGGS?------------------EES?-HHHHHHHHH----HHHH--HS?----------------------------------------------HHH-----HH---HHS?EEEE--E???TTT?EE--EEE-----------------------E------E?S?T-----------------------------------TT?---?E--EE-EEEE?HHHHHTT---EE-EE 3W5C|A PF13247.1_Fer4_11_seed 103 130 !Q:0,2|8,12|15,15|21,21|24,29|36,46|48,49|51,51|54,54|58,67|72,72|75,76|85,86|91,93|101,104|107,113|119,119|122,123 Q:3,7|13,14|16,20|22,23|30,35|47,47|50,50|52,53|55,57|68,71|73,74|77,84|87,90|94,100|105,106|114,118|120,121|124,129 ???EEEEE?????SS?HHHHH?TT?----?EEEETT-----------T??E-EE?TTT??----????HHHH?TT??EEEETTTT--EEEE??-TTHHHHT----TT??----?HHHHT?TT??EEEEEE 2IVF|B PF13249.1_Prenyltrans_2_seed 105 339 !Q:6,7|9,13|17,59|63,78|80,80|87,87|92,94|97,100|102,102|106,107|109,114|117,129|136,167|172,172|174,174|176,176|178,181|186,201|207,207|209,211|216,218|221,225|229,229|233,234|237,237|239,241|244,251|254,255|261,279|286,289|291,295|298,306|311,311|313,325|327,330|332,332|334,338 Q:0,5|8,8|14,16|60,62|79,79|81,86|88,91|95,96|101,101|103,105|108,108|115,116|130,135|168,171|173,173|175,175|177,177|182,185|202,206|208,208|212,215|219,220|226,228|230,232|235,236|238,238|242,243|252,253|256,260|280,285|290,290|296,297|307,310|312,312|326,326|331,331|333,333 HHHHHH--H-??--TTS---?--??------------------?----------------SSB----------------S?HHHHHH-HHHH---HH----H-HTT??T------TS-------------HHHHHH--------------------------------HHHH-H-T-T??--TTSS--???----------?GGGGT?G---GGTT?--SS??---HHH-HHH--HH-H---HH--------HH--TTTTS-------------------SHHHHH----H-----HH---------HHHH-H?----?-------T----T-S-???? 4GTR|B PF13263.1_PHP_C_seed 143 71 !Q:10,13|15,16|21,22|25,25|38,58|67,68 Q:0,9|14,14|17,20|23,24|26,37|59,66|69,70 HHHHHHHHHH----T??EEEE??BS-SGGGTTTTHHHH---------------------HHHHHHHT??EE 3DCP|A PF13275.1_S4_2_seed 202 77 !Q:2,4|6,6|8,10|21,21|35,36|44,47|50,53|61,66|68,69 Q:0,1|5,5|7,7|11,20|22,34|37,43|48,49|54,60|67,67|70,76 EE?-?S?S???HHHHHHHHTS?SSSSTTSHHHHHH--HHEETTB????SS????SSEEEEE------T--TEEEEEE 1P9K|A PF13277.1_YmdB_seed 140 321 !Q:3,4|26,28|35,35|39,39|41,41|46,47|59,59|64,65|81,82|84,84|86,93|95,97|101,101|103,106|108,108|111,111|115,120|125,126|138,139|141,141|144,152|154,158|169,171|174,180|184,186|188,188|190,195|201,201|203,203|220,225|235,235|238,239|242,242|246,246|251,254|259,259|266,266|277,287|289,290|292,294|296,297|307,307|311,312 Q:0,2|5,25|29,34|36,38|40,40|42,45|48,58|60,63|66,80|83,83|85,85|94,94|98,100|102,102|107,107|109,110|112,114|121,124|127,137|140,140|142,143|153,153|159,168|172,173|181,183|187,187|189,189|196,200|202,202|204,219|226,234|236,237|240,241|243,245|247,250|255,258|260,265|267,276|288,288|291,291|295,295|298,306|308,310|313,320 EEE??BBHHHHHHHHHHHHHHHHHHH-??SEEEEE?TBT-T-TTSS??HHHHHHHHHTT?SEEE??TTTTSSTTHHHHTTT-?S-S--------B???TTS?T----T?SS?SEE------EEEE--TTEEEEEEEEE??T-TS------???S----?HHHHHHHHHH---HH-------HTT--?S?E------EEEEE?S?HHHHHHHHHHTBTTBS------EEEEESSSS?BS??EE?TTS?EEES????BEES-SSBTTB?HHHHHHHHHH????-?---??B??S--?E--EEEEEEEEE?TTT??EEEEEEEE 2Z06|A PF13278.1_DUF4066_seed 51 228 !Q:1,2|4,4|7,7|21,21|23,33|35,35|48,48|51,60|63,63|65,66|69,69|71,71|78,80|84,84|86,86|90,93|95,97|100,102|110,111|118,138|142,145|166,166|169,171|183,183|186,189|198,206|212,213 Q:0,0|3,3|5,6|8,20|22,22|34,34|36,47|49,50|61,62|64,64|67,68|70,70|72,77|81,83|85,85|87,89|94,94|98,99|103,109|112,117|139,141|146,165|167,168|172,182|184,185|190,197|207,211|214,227 E??T-TB?HHHHHHHHHHHTT?S-----------S-SEEEEEEESSSE-EE----------BT-T??EE-E?SEEGGG---GGG?S-EEE----E???TT---HHHHHHT?-HHHHHH?-???----------------TTT---?EEEEETTHHHHHHHTTTTTT?EE???GGGHHHHHHTT?EE?---SSSEEEET---------TEEEE?-SGGGHHHHHHHHHH 3OT1|A PF13279.1_4HBT_2_seed 179 459 !Q:0,1|5,5|7,7|9,39|42,44|47,53|59,80|82,82|84,87|91,91|95,107|112,125|130,132|141,155|158,175|183,186|191,193|195,220|222,222|225,225|227,227|229,236|240,253|257,258|261,268|270,270|281,294|297,310|318,332|343,428|430,444 Q:2,4|6,6|8,8|40,41|45,46|54,58|81,81|83,83|88,90|92,94|108,111|126,129|133,140|156,157|176,182|187,190|194,194|221,221|223,224|226,226|228,228|237,239|254,256|259,260|269,269|271,280|295,296|311,317|333,342|429,429|445,458 ??GGG-B?T-------------------------------TS---BB----?--HHHHH----------------------H-H----HHH-HHH-------------HHHH--------------HHTT---TTTSTTTT---------------TT------------------TEEEEEE----EEEE?--S------------------------??B-TT?E-E--------EEE--------------EEE--EE--------E?SSEEEEEEEE--------------EE--------------TTEEEEE---------------EEEEEEEEEB-????--??-----------------------------------------------------------------------------B????-----------HHHHHHHHHHHHTT 1Z54|A PF13286.1_HD_assoc_seed 344 121 !Q:0,3|6,6|46,49|51,53|56,65|68,68|71,71|79,82|86,97|109,110 Q:4,5|7,45|50,50|54,55|66,67|69,70|72,78|83,85|98,108|111,120 ????HH-HHHHHHHHHHHHHHHTTTSHHHHHHHHHHHHHHHHHHHH----H---HH------?---GG-GS?HHHHTTH----HHH?-----------HHHHHHHHHHT??HHHHHHHHHH 2DQB|A PF13288.1_DXPR_C_seed 236 181 !Q:1,2|4,4|18,48|51,52|55,56|58,58|61,61|63,70|74,74|87,89|91,92|96,96|116,116|131,163 Q:0,0|3,3|5,17|49,50|53,54|57,57|59,60|62,62|71,73|75,86|90,90|93,95|97,115|117,130|164,180 E??S?THHHHHHHHHTTS?--?---------?--?------??-???-?HH--HH-?E-EE?B-???----TTT?HHHHHHHHHHHH--?T--THH-HHHHHHHHHHHHHHHTTSS?TTHHHHHHHHHHHH----------???-?---?-------------?SSHHHHHHHHHHHHHHH 1ONP|A PF13291.1_ACT_4_seed 182 94 !Q:0,8|18,18|20,21|36,36|39,39|43,43|49,57|85,85 Q:9,17|19,19|22,35|37,38|40,42|44,48|58,84|86,93 -???-----EEEEEEEEE-E??TTHHHHHHHHHTTS-SS?EEE-EEEEE-----?---SSEEEEEEEEEESSHHHHHHHHHHHTT?TTEEEEEE 2KO1|A PF13292.1_DXP_synthase_N_seed 331 380 !Q:3,3|9,9|14,14|34,35|37,41|44,44|64,64|68,68|79,79|90,90|102,103|106,107|111,111|113,113|115,116|118,119|124,124|136,141|144,144|146,146|148,151|153,155|157,173|196,197|201,206|215,318|320,321|329,329|339,339|352,357|359,363|365,369|371,371|379,379 Q:0,2|4,8|10,13|15,33|36,36|42,43|45,63|65,67|69,78|80,89|91,101|104,105|108,110|112,112|114,114|117,117|120,123|125,135|142,143|145,145|147,147|152,152|156,156|174,195|198,200|207,214|319,319|322,328|330,338|340,351|358,358|364,364|370,370|372,378 GGG?SSHHH-HTTS?GGGHHHHHHHHHHHHHHHS-?G-----GG?THHHHHTTHHHHHHHHHHS?TTT-SEEEESSSTT?HHHHHTTTTG-GGGGGTTSTTS??SS??TTT?T-T??S??SSSS?HHHHHHHHHHH------HH-H-H----T---S---------?-----??EEEEEETTGGGSHHHHHHHHHH--HHH-?-?--SEEEEEEE???????----------??????-???---?????---???---????????????-?-----??-----??????????----????????---?----?---H--HHHHHTT?EEEEEEETT?HHHHHHHHHHHH------H-----S----?S-EEEEEEE? 3DVA|A PF13298.1_LigD_N_seed 134 163 !Q:3,7|12,14|26,26|35,40|42,42|45,45|52,52|57,57|63,64|67,68|71,75|77,79|90,90|93,93|95,106|110,121|124,137|141,141|152,152|154,154|156,156 Q:0,2|8,11|15,25|27,34|41,41|43,44|46,51|53,56|58,62|65,66|69,70|76,76|80,89|91,92|94,94|107,109|122,123|138,140|142,151|153,153|155,155|157,162 EEE-----ESSS--?EEEEEEEETTE-EEEEEETT??---?S?TT?EEEEEE-EEEE?GGGGG??EE??TT?????E---EEEEEEEEEE-ES-S-----------?HHH------------HH--------------HHT-EEEEEEEESS?E-E-EEEEEE 3TA7|A PF13302.1_Acetyltransf_3_seed 406 395 !Q:4,12|15,17|24,24|28,28|30,37|40,40|43,46|49,51|55,55|57,61|70,73|75,76|78,87|90,95|97,117|122,147|151,154|156,166|168,184|186,190|192,192|196,196|200,214|219,246|253,253|256,256|259,263|265,265|268,268|271,278|281,281|293,298|302,306|308,308|310,313|316,347|349,367|370,370|375,375|377,378|380,380|387,387|393,393|395,395 Q:0,3|13,14|18,23|25,27|29,29|38,39|41,42|47,48|52,54|56,56|62,69|74,74|77,77|88,89|96,96|118,121|148,150|155,155|167,167|185,185|191,191|193,195|197,199|215,218|247,252|254,255|257,258|264,264|266,267|269,270|279,280|282,292|299,301|307,307|309,309|314,315|348,348|368,369|371,374|376,376|379,379|381,386|388,392|394,394 SEEE??-?-?---GG---GHHHHH-HHH-T--?-----TT-TT----TT---STT?S?---?HHHHHHHH----H--H----------TT??-???E---------------------EEEE--------------------------ETT----T-----------T-----------------E-----E-EEE-EEE---------------EEEE----------------------------TTTEEE-EE-EE-----E?GG-GT--------TS-SHHHHHHHHHH------HHH-----H-H----TS?------?------------------------S-------------------EE-EEEE?T--T?HHHHHH-HHHTT?E- 2PR8|A PF13304.1_AAA_21_seed 220 495 !Q:5,6|10,10|12,13|22,47|51,64|68,70|75,77|86,86|92,92|105,140|151,151|168,169|183,220|238,238|242,314|318,318|322,324|330,335|338,340|345,345|359,381|384,386|389,392|396,398|401,403|405,408|412,415|420,424|428,440|446,476|481,481|485,488|492,492|495,495 Q:0,4|7,9|11,11|14,21|48,50|65,67|71,74|78,85|87,91|93,104|141,150|152,167|170,182|221,237|239,241|315,317|319,321|325,329|336,337|341,344|346,358|382,383|387,388|393,395|399,400|404,404|409,411|416,419|425,427|441,445|477,480|482,484|489,491|493,494 EEEEE??TTT?S--THHHHHHH--------------------------HTS??????????????TTB???BTTB???SEEEEEEE-EESSS?EEEEEEEEETTS?-----------------------------------EEEEETTEEE?HHHHHHHTTTSSTTTT??SEEEHHHHHHHHT?????????????---------------??????????HHHHHHHHHHHHHHHTS?EEE??????????????--------------------------------------------------------???EEE?TTS???BGGGS-----?HH---HHHH-HHHHHHHHHTTTS??---------------------SE---EE----EES?-?SS-??H----HHH----HHHH-----HHH-------------HHHTT-------------------------------TSEE-EEE???-TTG-GG- 4I99|A PF13305.1_WHG_seed 239 184 !Q:22,32|36,36|39,53|56,57|67,67|69,72|74,84|86,99|105,107|111,111|113,114|116,117|120,127|131,138|140,143|146,146|152,154|157,158|164,164|169,171|175,180|182,182 Q:0,21|33,35|37,38|54,55|58,66|68,68|73,73|85,85|100,104|108,110|112,112|115,115|118,119|128,130|139,139|144,145|147,151|155,156|159,163|165,168|172,174|181,181|183,183 HHHHHHHHHHHHHSHHHHHHHH-----------HHH-TS---------------TT??HHHHHHHHH-H----H-----------H--------------HHHHH---HHH-H--H--HT--------TSB??------S?---HH-HHHHH---HH--HHHHH-HHHH---HHT------T?S 3CJD|A PF13306.1_LRR_5_seed 205 219 !Q:3,5|10,10|13,14|19,19|21,21|24,28|30,31|33,38|40,43|45,45|52,52|55,59|62,69|71,72|74,77|80,80|85,85|88,89|92,107|109,110|112,114|117,118|121,121|126,133|135,135|139,146|148,149|151,157|160,160|163,163|165,166|168,168|171,172|175,179|182,182|184,187|189,190|192,196|199,201|203,203|206,208|212,214|217,218 Q:0,2|6,9|11,12|15,18|20,20|22,23|29,29|32,32|39,39|44,44|46,51|53,54|60,61|70,70|73,73|78,79|81,84|86,87|90,91|108,108|111,111|115,116|119,120|122,125|134,134|136,138|147,147|150,150|158,159|161,162|164,164|167,167|169,170|173,174|180,181|183,183|188,188|191,191|197,198|202,202|204,205|209,211|215,216 EEE?--TTTT-TT-?TTEE-E-EE-??--T--T--??--E----E?TTTTTT?TT-??--EE-?--?--?T--T--??EE?TTTT-TT-?TT-?-???-??-----?-T--T-??EE?-TT-TTTT??--?---S-EEE--?--?--T--T--??---EE?TT-T--T-TT-?TT-?-?-EE-E-??-T--T??---EE--?T-TT---TTT-?-TT?? 2A0Z|A PF13307.1_Helicase_C_2_seed 152 416 !Q:5,5|7,7|9,9|11,13|15,15|22,22|32,32|34,39|41,68|70,71|73,85|87,87|89,94|96,111|113,119|121,122|128,144|149,152|154,159|161,198|200,200|202,203|209,210|212,232|237,238|241,258|270,270|272,276|279,331|333,333|335,342|345,346|348,348|366,367|371,375|382,382|387,389|391,395|398,401|403,403|406,409|412,412 Q:0,4|6,6|8,8|10,10|14,14|16,21|23,31|33,33|40,40|69,69|72,72|86,86|88,88|95,95|112,112|120,120|123,127|145,148|153,153|160,160|199,199|201,201|204,208|211,211|233,236|239,240|259,269|271,271|277,278|332,332|334,334|343,344|347,347|349,365|368,370|376,381|383,386|390,390|396,397|402,402|404,405|410,411|413,415 HHHHH-H-H-H?--S?EEEEES?HHHHHHHTS-S-?---?S------------?--?------------E--E--??---------T-T?--?--S----------------H-------H--HHHHH-----------------HHHT----T------S------------------------------------??E-E--EEETT--S???--??????---???--??EEEE--SS???----------???-?HHHHHHHHHHH-H-----HH-----------------------------------------------------S?H--------HH--H-HTHHHHHHHHHHHHHTT??STT---??EEEEEE?GGGG---G-----GG----G-GS----TT?EEE 3CRV|A PF13308.1_YARHG_seed 105 118 !Q:5,5|8,11|14,14|25,27|44,47|49,49|58,58|60,60|63,66|68,80|82,93|97,98|106,110|117,117 Q:0,4|6,7|12,13|15,24|28,43|48,48|50,57|59,59|61,62|67,67|81,81|94,96|99,105|111,116 HHTHH-HH----HH?TTHHHHHHTS?--HHHHHHHHHHHHHTTT????S-HHHHHHHH-T?TT????T-------------T??----------GGG??HHHHHHH-----HHHHHH? 4G2A|A PF13324.1_GCIP_seed 12 292 !Q:26,28|54,54|58,58|85,105|118,118|151,188|192,193|225,235|238,238|265,265|268,269 Q:0,25|29,53|55,57|59,84|106,117|119,150|189,191|194,224|236,237|239,264|266,267|270,291 HHHHHHHHHHHHHHHHHHHHHTTSSS???HHHHHHHHHHHHHHHHHHHHHHTTS?GGG?HHHHHHHHHHHHHHHHHHHHHHHHHH?-----???????????????HHHHHHHTTTTS?SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS?????-------??????????????????????????TTS??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?---------?TT?HHHHHHHHHHHHHHHHHHHHHHHHHS-SS??HHHHHHHHHHHHHHHHHHHHHH 3AY5|A PF13326.1_PSII_Pbs27_seed 61 227 !Q:0,49|51,81|83,84|86,86|88,92|94,99|116,117|120,125|128,128|154,154|158,179|187,187|203,207|211,211 Q:50,50|82,82|85,85|87,87|93,93|100,115|118,119|126,127|129,153|155,157|180,186|188,202|208,210|212,226 -----------------------------??---?--------------?S-------------------------------S??S-S??---S?-----HHHHHHHHHHHHHHHH--HS?-----TT?TTHHHHHHHHHHHHHHHHHHTHHHH?SSS-------------------?--HHHHHHH-HHHHHHHHHHHHHSS?-???HHH-HHHHHHHHHHHHHHH 2KND|A PF13328.1_HD_4_seed 118 316 !Q:10,25|27,27|29,29|33,33|45,46|49,51|55,58|60,67|70,76|79,80|90,99|101,114|116,125|127,130|132,133|135,139|142,153|156,157|160,163|165,168|180,180|183,227|229,230|232,234|238,247|249,252|256,257|271,292|308,308|314,314 Q:0,9|26,26|28,28|30,32|34,44|47,48|52,54|59,59|68,69|77,78|81,89|100,100|115,115|126,126|131,131|134,134|140,141|154,155|158,159|164,164|169,179|181,182|228,228|231,231|235,237|248,248|253,255|258,270|293,307|309,313|315,315 HHHHHHHHTT----------------T?B?TTS?BTTHHHHHHHH--HH---HHT----T---??---HH-------HH--HHHHHTTHH----------H--------------H----------S----S??H-----HH------------HH--HH----H---?HHHHHHHHHHH-HH??????------------------???-------?????---???S-?T---TTS----???---H----HHH--HHHHHHHHHHHHT?-----???--???-------?HHHHHHHHHHTHHHH-HHHTT?H 1VJ7|A PF13336.1_AcetylCoA_hyd_C_seed 251 222 !Q:0,1|9,13|15,19|21,26|32,34|40,52|58,59|69,70|77,78|81,82|85,85|87,93|95,98|101,103|116,117|120,122|128,129|133,134|136,143|145,147|149,152|154,157|159,159|166,167|170,171|175,175|179,180|190,190|192,192|195,196|207,207|210,210 Q:2,8|14,14|20,20|27,31|35,39|53,57|60,68|71,76|79,80|83,84|86,86|94,94|99,100|104,115|118,119|123,127|130,132|135,135|144,144|148,148|153,153|158,158|160,165|168,169|172,174|176,178|181,189|191,191|193,194|197,206|208,209|211,221 ??HHHHHHH-----T-----T-----?TTEEE-??HHHHT---------?---HHHHT--TSSSEEEEE??SEEETT??EE??ST-T-------S?--?SB???THHHHHHHHHHS--TT--?EEEEE??SEE--T--------T---T----T----E-ESEESS??TT??EEE?TTT??EEEETTEEE-E?TT??HHHHHHHHHT-TS?HHHHHHHHHHH 3S8D|A PF13341.1_RAG2_PHD_seed 6 79 !Q:2,2|4,4|9,12|16,19|23,23|27,29|32,33|36,36|38,39|42,42|48,49|61,65|71,71|73,78 Q:0,1|3,3|5,8|13,15|20,22|24,26|30,31|34,35|37,37|40,41|43,47|50,60|66,70|72,72 SS?S?SSTT????TTT????SSS?SSS???EE??SS-S??EE?SGGGT??HHHHHHHTTSS?????STTSS?S??---- 2JWO|A PF13343.1_SBP_bac_6_seed 82 331 !Q:2,2|7,15|28,28|30,33|37,37|41,44|48,48|53,61|66,66|68,68|71,72|90,90|94,102|109,109|116,118|122,122|124,134|148,149|152,155|177,177|180,180|190,200|218,225|230,231|234,236|245,245|249,253|271,271|281,293|297,304|311,311|317,317|322,323 Q:0,1|3,6|16,27|29,29|34,36|38,40|45,47|49,52|62,65|67,67|69,70|73,89|91,93|103,108|110,115|119,121|123,123|135,147|150,151|156,176|178,179|181,189|201,217|226,229|232,233|237,244|246,248|254,270|272,280|294,296|305,310|312,316|318,321|324,330 SS?SSBB?-------?BGGGHHHHHHHT?B????TTS?TTG----GGB?GGGS-------??TTST-T?SS?-EEEEEEEEEEEEETTTS?TTT?-------?SSGGGG-SGGGTT--?EEE?S----------?HHHHHHHHHHHTT??TT???-HHHHHHHHHHHHHTGGGEEEE?SS?THHHHHTTS----------?SEEEEEHHHHHHHHTTS?------?EEEE??TT-??EEEEEEEB?BTT----?TTHHHHHHHHHHHHSHH-HHHHHHHHH?---------???SBS--------TTTTTS?HHHHT?TTTS??HHHHHHS 3G7W|A PF13344.1_Hydrolase_6_seed 179 233 !Q:4,4|10,29|31,37|41,42|44,46|60,60|62,87|94,97|100,100|109,110|113,113|115,117|119,137|139,139|141,145|161,165|167,169|171,204|210,212|214,218|220,221|232,232 Q:0,3|5,9|30,30|38,40|43,43|47,59|61,61|88,93|98,99|101,108|111,112|114,114|118,118|138,138|140,140|146,160|166,166|170,170|205,209|213,213|219,219|222,231 EEEE?BTTTE--------------------E-------TTE--E--?TTHHHHHHHHHHH-T------------------------??EEEEES?--?SS?HHHHHHHH--HT-T---T-??-----?--------?-G-G-----GEEEHHHHHHHHHHH-----H---S?------------------------------???EEEES?--H-----H--HHHHHHHHTS? 3RF6|A PF13345.1_DUF4098_seed 289 145 !Q:0,0|3,4|6,6|8,9|12,13|18,20|23,24|26,26|30,31|33,36|38,40|44,46|49,49|52,52|54,54|56,57|60,63|66,66|69,71|74,74|78,79|86,87|90,91|93,93|96,98|100,101|103,105|107,109|111,112|116,118|123,124|126,127|129,130|132,133|135,136|138,138|141,142|145,145 Q:1,2|5,5|7,7|10,11|14,17|21,22|25,25|27,29|32,32|37,37|41,43|47,48|50,51|53,53|55,55|58,59|64,65|67,68|72,73|75,77|80,85|88,89|92,92|94,95|99,99|102,102|106,106|110,110|113,115|119,122|125,125|128,128|131,131|134,134|137,137|139,140|143,144 ?EE--E-E--EE--EEEE-?-TT?-E-EEE--S-?--E---EEE---EE-EE-E-E?-SS--?-EE-EE?--SE-EEE--EEEEEE?-SS?-E-EE---E--E---E---E--EEE---EEEE--E--E?-S--S?-E-EE--EE- 3JX8|A PF13347.1_MFS_2_seed 92 847 !Q:0,3|9,11|13,13|22,23|30,30|41,42|47,53|65,73|80,88|91,92|113,202|206,223|228,265|267,269|277,277|285,286|290,291|299,299|303,305|320,320|323,324|335,345|349,513|529,531|539,540|542,542|553,553|557,571|593,593|608,609|637,639|647,653|668,668|671,671|677,680|684,684|706,710|713,713|749,758|761,762|783,783|789,795|799,804|806,806|809,820|836,836|842,846 Q:4,8|12,12|14,21|24,29|31,40|43,46|54,64|74,79|89,90|93,112|203,205|224,227|266,266|270,276|278,284|287,289|292,298|300,302|306,319|321,322|325,334|346,348|514,528|532,538|541,541|543,552|554,556|572,592|594,607|610,636|640,646|654,667|669,670|672,676|681,683|685,705|711,712|714,748|759,760|763,782|784,788|796,798|805,805|807,808|821,835|837,841 ????HHHHH---H-HHHHHHHH--HHHHHH-HHHHHGHHHH--HHHH-------HHHHHHHHHHT---------HHHHHH---------HS?-SHHHHHHHHHHHHHHHHHTT?----------------------------------------------------------------------------------------?SST------------------HHHH--------------------------------------H---HHHHHHH-HHHHHHH--HHH--HHHHHHS?TTS---TTTTHHHHHHHHHH-HH--HHHHHHHTTS----------?SHH---------------------------------------------------------------------------------------------------------------------------------------------------------------------HHHHHHHHHHHHHHH---HHHHHHS??S?HHHHHHHHHH?SSS---------------HHHHHHHHHHHHHHHHHHSSS?SSTTHHHHHHHHHH--HHHHHSSSHHHHTHHHHHHHHHTTTST---HHHHTTH-------HHHHHHHHHHHHHH-HH-TTSSS---?SHH-HHHHHHHHHHHHHHHHHHHHH-----TT?HHHHHHHHHHHHHHHHHHHHHTTTTHHHHHTTTTS?---------SS??HHHHHHHHHHHHHHHHHHHH-HGGGG-------GGT------S?SS------------HHHHHHHHHHHHHHH-HHHHT????? 4LDS|A PF13348.1_Y_phosphatase3C_seed 223 85 !Q:2,3|14,16|28,28|34,40|43,43|46,46|51,51|69,69|71,72|84,84 Q:0,1|4,13|17,27|29,33|41,42|44,45|47,50|52,68|70,70|73,83 HH--HHHHHTTTTS???HHHHHHHHTTT?HHHHS?---?--HH-HH-HHHH-HHHHHHHSSHHHHHHHT-T??HHHHHHHHHHH? 1YWF|A PF13350.1_Y_phosphatase3_seed 403 315 !Q:1,1|7,18|20,22|25,43|45,45|54,55|58,62|64,67|69,69|76,77|81,82|87,89|97,100|102,119|121,126|128,128|130,130|132,132|135,143|145,207|209,211|213,215|224,225|233,236|243,246|251,252|258,262|264,264|266,273|278,278|298,300|302,302|305,305 Q:0,0|2,6|19,19|23,24|44,44|46,53|56,57|63,63|68,68|70,75|78,80|83,86|90,96|101,101|120,120|127,127|129,129|131,131|133,134|144,144|208,208|212,212|216,223|226,232|237,242|247,250|253,257|263,263|265,265|274,277|279,297|301,301|303,304|306,314 S?EEGGG------------T--?TT-------------------S?TTSEEEES??TT?--?-H----H-HHHHHH--HHT??EEEE???HHHHHHH---?S---------?-???----T------T?E-E-EE?--???--?S?-?-???-------------------?????-??--?-????????-???????????????-H---H---HHHHHHHH--HHHGGGS----TTHHHH----HHHH--HHHHH-----T-T---?---?EEEE?SSSSSHHHHHHHHHHHHTT?-?H-HH-HHHHHHGGG 2GJT|A PF13353.1_Fer4_12_seed 147 269 !Q:5,7|9,11|13,15|17,21|25,26|29,32|34,40|42,43|45,50|52,55|59,72|75,95|100,107|121,121|125,128|132,138|146,146|150,153|156,157|159,160|167,167|175,183|189,197|199,204|206,219|227,227|229,230|233,233|237,239|241,242|246,246|249,252|254,255|258,260|263,263 Q:0,4|8,8|12,12|16,16|22,24|27,28|33,33|41,41|44,44|51,51|56,58|73,74|96,99|108,120|122,124|129,131|139,145|147,149|154,155|158,158|161,166|168,174|184,188|198,198|205,205|220,226|228,228|231,232|234,236|240,240|243,245|247,248|253,253|256,257|261,262|264,268 SSSSS---S---E---E-----EEE--ES?--?S--?--??T--T--?---S?---GGG?------------?SS--------------------?SEEE---?----HHHHHHHHGGGHH-HHH----HHT------?EEEEEES?GGG----GH--H--HHHHHH-HHHHTTT---?--?--EEEEE??????-??H------H--------------HHHHHHT?S--EE-EEE???S-?HHH-HH----H--HT---SS?SHHHH 4K39|A PF13354.1_Beta-lactamase2_seed 138 489 !Q:3,5|7,9|12,14|17,19|24,25|28,28|34,37|39,42|44,47|49,52|56,61|68,71|73,77|81,85|89,93|97,99|101,102|105,120|123,128|132,132|135,138|141,144|146,147|161,162|174,177|179,179|183,185|193,193|196,196|199,200|202,203|205,211|214,270|273,294|297,299|309,312|317,320|322,338|340,340|342,342|347,355|361,367|369,376|378,378|380,380|382,387|389,396|398,398|400,400|403,405|408,408|410,425|428,434|436,436|439,441|447,455|458,462|467,469|474,474|476,477|481,481|483,483 Q:0,2|6,6|10,11|15,16|20,23|26,27|29,33|38,38|43,43|48,48|53,55|62,67|72,72|78,80|86,88|94,96|100,100|103,104|121,122|129,131|133,134|139,140|145,145|148,160|163,173|178,178|180,182|186,192|194,195|197,198|201,201|204,204|212,213|271,272|295,296|300,308|313,316|321,321|339,339|341,341|343,346|356,360|368,368|377,377|379,379|381,381|388,388|397,397|399,399|401,402|406,407|409,409|426,427|435,435|437,438|442,446|456,457|463,466|470,473|475,475|478,480|482,482|484,488 TTT--?E---EE---EE---BTTS?-EE?GGGGH----H----H----H----HHH------HHHHHH----T-----TSS?----SSS-----EEE??-T--TT-------?--?--?--SS-----?SGG-GS--?-TT-?--E--EEHHHHHHHHHHS??HHHHHHHHHHT----T?HHH---HHHHHHH-TT?TT-?B??S?------TT--------------------------------------------------------?TT-------?-----?--?-----EE--?HHHHHHHHH----HHHT----T--------------?--S-S?HHHH---------HHHHH-------H--------H-T-S-----?S?-----?-S-S-GG---GG-S-?--------------TT---?---E-EE---EEEEE-------?-SS-----EEEE---EEEE-E?-TTS?E-EEEEE 1IYP|A PF13356.1_DUF4102_seed 255 214 !Q:0,2|8,16|18,23|25,32|34,41|46,47|49,54|57,65|69,69|73,74|76,76|78,80|82,85|87,88|92,92|96,111|115,116|119,120|123,128|130,132|134,134|137,138|142,145|148,165|167,173|189,189|191,191|193,193|195,198|200,200|204,208|213,213 Q:3,7|17,17|24,24|33,33|42,45|48,48|55,56|66,68|70,72|75,75|77,77|81,81|86,86|89,91|93,95|112,114|117,118|121,122|129,129|133,133|135,136|139,141|146,147|166,166|174,188|190,190|192,192|194,194|199,199|201,203|209,212 ??-HHHHH---------H?--???S--------S?-------EEEE--E------ET---------TEE-EEE?-T-T---S---?E--EEE-EEE----------------EET--TE--EE------E---E-EE--EEE----TT------------------S------?HHHHHHHHHHHHHHH-H-T-T??--G-GGS----?GGGS? 3JTZ|A PF13358.1_DDE_3_seed 69 274 !Q:12,18|23,23|27,32|35,37|40,47|54,54|60,62|71,99|101,109|111,115|122,122|138,152|156,159|161,162|167,174|181,190|194,224|227,227|230,238|241,241|245,245|262,266 Q:0,11|19,22|24,26|33,34|38,39|48,53|55,59|63,70|100,100|110,110|116,121|123,137|153,155|160,160|163,166|175,180|191,193|225,226|228,229|239,240|242,244|246,261|267,273 GEEEEEEEEEES???-???EEEE?SSS?--???EE???TT?------?EEEEEE-EEESS---SEEEEEEE----------------------------?S---------S?-???HHHHHH-HHHHHHHHHHHHSTT??-------??????EEE????T--TTTS--------HHHHHH----------HHH-------------------------------TT?EE???-----?TT?GGG?HHHHTHHHHHHHHHTT--???SSHHHHH 3HOT|A PF13360.1_PQQ_2_seed 112 509 !Q:5,5|11,12|14,17|19,20|26,30|32,34|36,91|97,98|101,101|110,112|114,120|133,134|141,143|146,148|150,173|176,176|181,185|189,200|204,205|210,214|217,217|221,222|224,246|250,250|253,265|268,269|273,276|279,283|288,292|296,296|298,302|307,317|325,326|328,329|335,336|338,354|357,357|360,363|365,365|369,371|376,379|382,384|389,390|394,397|399,401|403,407|411,411|416,421|424,424|426,426|430,430|432,450|453,453|466,466|468,486|488,491|502,502 Q:0,4|6,10|13,13|18,18|21,25|31,31|35,35|92,96|99,100|102,109|113,113|121,132|135,140|144,145|149,149|174,175|177,180|186,188|201,203|206,209|215,216|218,220|223,223|247,249|251,252|266,267|270,272|277,278|284,287|293,295|297,297|303,306|318,324|327,327|330,334|337,337|355,356|358,359|364,364|366,368|372,375|380,381|385,388|391,393|398,398|402,402|408,410|412,415|422,423|425,425|427,429|431,431|451,452|454,465|467,467|487,487|492,501|503,508 TTSEE-EEEET--T----T??EEEEE-----E?-?S------------------------------------------?-------------EEEEE--EE-ETTEEEEE---E-------TTSEEEEEETTT??EEEEEE?--SS???S?---------------------?-EE?SSEE-----EEE?-----------TTS--EEEE-----EE-TTT??E-----------------------EEE-EE??-------?-??TT--EEE????EE?----SSEE-----EEE?T-----TSEE-----------EEEETTT??E--EEEEE?-S???-------------?SS?TT----S?EEE???EEEE----TT---EEEE??STT----E---E-----EEE-ETTT??----EE-E-EEE-S??----------------?SE-EEEETTEEEEEE-T-------------------T----TEEEEEETTS?SEEEEE 3Q7M|A PF13361.1_UvrD_C_seed 35 779 !Q:3,3|5,5|9,9|21,49|52,52|55,63|65,65|68,73|85,92|98,100|107,121|126,128|131,133|144,144|160,168|170,170|176,177|193,193|197,197|200,200|202,214|225,227|229,232|235,254|259,445|452,453|469,492|497,497|499,499|504,505|507,507|522,522|530,533|545,546|550,551|559,572|576,593|595,597|608,632|644,645|652,658|662,705|709,737|743,744|746,746|752,754 Q:0,2|4,4|6,8|10,20|50,51|53,54|64,64|66,67|74,84|93,97|101,106|122,125|129,130|134,143|145,159|169,169|171,175|178,192|194,196|198,199|201,201|215,224|228,228|233,234|255,258|446,451|454,468|493,496|498,498|500,503|506,506|508,521|523,529|534,544|547,549|552,558|573,575|594,594|598,607|633,643|646,651|659,661|706,708|738,742|745,745|747,751|755,778 EEE?B?SSS?HHHHHHHHHHH-----------------------------TT?SS????---??B?SS???-??EEEEEESSHHH--------HHHHH---HHHHHH---------------HHTT---TS??-GGGEEEEESS-GGGHHHHHHHHHHTT-??------E-EETTS??GGGSHHHHHHHHHHH-HHH?TT?H-------------HHHHHHHTSS?-?T----TT?????????--?????????TTTT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSHHHH??THHHHHHHHHHHHHH------------------------HHHH-H-HTTT--S?HHHHHHHHHHHTSH-HHHHHHH?---SHHHHHHHHHH--HHH--HHHHHHH--------------HHH?-----------------S???HHHHHHHHTT??????????????????-------EEEEEGGGGTT??EEEEEE???----BTB--------------------------------------------TTT-----------------------------BTTTT--T?HHHHH---HHHHHHHHHHTTEEEEEEEEEESS 1W36|B PF13362.1_Toprim_3_seed 51 147 !Q:0,1|14,16|23,23|25,25|28,29|33,34|50,51|53,53|57,57|59,60|64,66|71,81|90,97|102,102|104,104|110,112|115,124|126,132|137,138|143,143|147,147 Q:2,13|17,22|24,24|26,27|30,32|35,49|52,52|54,56|58,58|61,63|67,70|82,89|98,101|103,103|105,109|113,114|125,125|133,136|139,142|144,146 ??EEESSHHHHHHH---HHHHTT?S?EE??TTT--TTTHHHHHHHTHHHH--T-TBS?E--EEE??-SSHH-----------HHHHHHHH--------HHHS?T-TTEEE???SS----------S-------SHHH--HHTT-TTH- 1NUI|A PF13363.1_BetaGal_dom3_seed 56 94 !Q:1,5|10,14|22,23|27,27|38,41|43,44|56,57|65,66|68,68|70,71|81,82|85,85|87,87|89,90 Q:0,0|6,9|15,21|24,26|28,37|42,42|45,55|58,64|67,67|69,69|72,80|83,84|86,86|88,88|91,93 E?????SSSS?????SHHHHHT??EEE?SSEEEEEEEE----T--TEEEEEEEBSS?-EEEEEES??T-T??EEEETTEEE??EE?T-T??EEE 1TG7|A PF13364.1_BetaGal_dom4_5_seed 105 193 !Q:4,4|12,16|19,26|29,34|36,43|46,46|48,49|63,67|70,72|75,76|79,82|86,98|101,103|106,114|127,127|130,134|138,138|140,149|154,154|156,159|163,163|165,169|172,177|188,188|192,192 Q:0,3|5,11|17,18|27,28|35,35|44,45|47,47|50,62|68,69|73,74|77,78|83,85|99,100|104,105|115,126|128,129|135,137|139,139|150,153|155,155|160,162|164,164|170,171|178,187|189,191 HHHH-TTTTSSS??--?TT--------SB---???T--------TT?B--SSSEEEEEEEEEE?-???TT---EE??EE----EEE?---------???SS???EE---------EEEEETTEEEEE-EE-----TTT?S?--------?EEEE?B----TTB?T-----TS------EEEEEEEEEE?STT? 1TG7|A PF13365.1_Trypsin_2_seed 318 469 !Q:3,4|6,9|12,14|20,46|51,69|75,141|144,144|151,151|155,155|157,157|160,211|219,222|224,256|260,261|266,268|271,275|277,278|282,283|286,286|293,383|394,406|408,430|435,438|440,444|452,452|455,457|460,464 Q:0,2|5,5|10,11|15,19|47,50|70,74|142,143|145,150|152,154|156,156|158,159|212,218|223,223|257,259|262,265|269,270|276,276|279,281|284,285|287,292|384,393|407,407|431,434|439,439|445,451|453,454|458,459|465,468 EEE--E----EE---ETTTT---------------------------EEEE-?-----------------HHHHT-------------------------------------------------------------------TE-EEEEEE?TTS?E-EE---------------------------------------------------?EEEEEET----T---------------------------------TTE--EEEE???SS?????B??GGG??TT?EEEEEE???????-------------------------------------------------------------------------------?????EEEEEEEEEE?????????????E-----------------------EESS???-G-----GGTTSEE-EE---TT??---EEEE 3LGY|A PF13370.1_Fer4_13_seed 110 108 !Q:1,8|12,16|22,22|29,29|33,33|38,38|40,45|47,56|58,61|64,65|67,77|79,81|86,90|100,100|103,104 Q:0,0|9,11|17,21|23,28|30,32|34,37|39,39|46,46|57,57|62,63|66,66|78,78|82,85|91,99|101,102|105,107 E------?-TTT?????HHHHH?TTTEEE?TTS?EEET-T------T----------T----TS--S----------?S???GGGH-----HHHHHHHHH?TT??EEE 1ROF|A PF13371.1_TPR_9_seed 103 91 !Q:5,5|10,10|25,30|33,36|52,52|65,68|71,71|73,82|84,84 Q:0,4|6,9|11,24|31,32|37,51|53,64|69,70|72,72|83,83|85,90 HHHHH-HHHT?HHHHHHHHHHHHHH-----?TT---?HHHHHHHHHHHHHHT?HHHHHHHHHHHH----HH?T----------T?HHHHHH 4GA2|A PF13372.1_Alginate_exp_seed 23 540 !Q:0,3|14,14|18,18|24,28|61,92|105,111|113,116|119,119|121,121|135,135|151,155|159,159|171,175|179,180|182,183|185,202|221,221|235,260|263,271|289,289|292,294|315,326|346,351|365,368|375,379|382,384|387,387|394,394|399,399|403,405|421,424|445,447|449,449|451,474|477,478|492,492|495,498|507,507|522,522|526,526|530,530|532,532 Q:4,13|15,17|19,23|29,60|93,104|112,112|117,118|120,120|122,134|136,150|156,158|160,170|176,178|181,181|184,184|203,220|222,234|261,262|272,288|290,291|295,314|327,345|352,364|369,374|380,381|385,386|388,393|395,398|400,402|406,420|425,444|448,448|450,450|475,476|479,491|493,494|499,506|508,521|523,525|527,529|531,531|533,539 ????EEEEEEEEEE-EEE?TTTTS?????EEEEEEEEEEEEEEEETTEEEEEEEEEEEESS?????????????????????-----????--SEEEEEEEEEEE-------E?--?SS-S?TTEEEEEEEEEEE?TTSSSBEEEEEEEEE-----EEE?SSEEEEEEEEE?????BSS??S??T------------------TTTTEEEEEEEEEEEEET-TEEEEEEEEEEEE??????--------------------TT?????????EEEEEEEEEEEEEESTT?TT??-SSEEEEEEEEEEEEEEEEEE????????-???EEEEEEEEEEEEEEEEEEE?-----SSSEEEEEEEEEE?-??SGGGTT?????SB???EE?TTSSSS?EETT?TTT???SSSEEEEEEEEEEEE----TTTEEEEEEEEEEEESSTTS???S?S??------------------????TT??EEEEEEEEEEEEE?SS????TTSTTTTT?SSSEEEEEEEEEEE?TTT?TTS?S?EEEEEEE 4AZL|A PF13374.1_TPR_10_seed 291 63 !Q:8,8|11,12|18,18|20,21|25,25|32,32|34,34|42,45|47,48|50,54|56,60 Q:0,7|9,10|13,17|19,19|22,24|26,31|33,33|35,41|46,46|49,49|55,55|61,62 HHHHHHHH-HH--HHHHT-T??TTH-HHHHHH-H-HHHHHHH----H?-T-----T?----HH 4HOU|A PF13377.1_Peripla_BP_3_seed 246 317 !Q:4,4|9,10|15,18|21,37|50,57|63,63|68,72|77,80|91,92|94,137|142,149|153,156|158,161|166,167|176,176|179,179|185,185|187,198|200,203|205,205|207,207|210,211|215,216|219,232|236,237|243,252|256,258|264,264|275,277|279,285|288,290|292,293|295,299|302,306|308,308|311,313|316,316 Q:0,3|5,8|11,14|19,20|38,49|58,62|64,67|73,76|81,90|93,93|138,141|150,152|157,157|162,165|168,175|177,178|180,184|186,186|199,199|204,204|206,206|208,209|212,214|217,218|233,235|238,242|253,255|259,263|265,274|278,278|286,287|291,291|294,294|300,301|307,307|309,310|314,315 HHHH-HHHT-?SSEE----EE?--------------??TTSHHHHHHHHH--------HHHHH-HHTT??-??GGGB????SSHHHHHHHH--H--------------------------------------------HHHT--------SSS??--S----EEEE--SSHHHHHH-HH-HHHHH-T------------T??--T-T-TT?-EEE?-SB--------??----TTG--GGSSS-??-----?-EEE?-?HHHHH-HHHHHHHHHH---H-------HT???S??E-----EE-???-E-EE??-SS? 1BYK|A PF13378.1_MR_MLE_C_seed 1015 236 !Q:3,3|5,8|19,19|22,29|31,34|38,39|44,44|55,55|61,66|68,74|76,77|82,82|88,88|90,91|95,110|112,123|125,127|131,131|134,147|149,149|151,176|178,186|188,189|191,199|202,202|204,204|207,209|211,211|213,218|220,221|223,224|226,230|234,235 Q:0,2|4,4|9,18|20,21|30,30|35,37|40,43|45,54|56,60|67,67|75,75|78,81|83,87|89,89|92,94|111,111|124,124|128,130|132,133|148,148|150,150|177,177|187,187|190,190|200,201|203,203|205,206|210,210|212,212|219,219|222,222|225,225|231,233 SSS-S---?SHHHHHHHHH-TT?-?-----S----EEB??HHHH?HHHHHHHHHH-HHHHT??---?B???---?S??HHHH-HHHHH-H--HHT?-?-------------S--------????B???HHH-HT--------------T-T?---?--------------------?B---------S--S-?-?---?-EE-T-TE---E-E?--?--S--S--S-----BTS?? 4HCH|A PF13379.1_NMT1_2_seed 82 353 !Q:0,2|4,4|6,7|12,12|21,21|34,53|55,55|58,60|65,65|67,67|78,78|84,84|90,90|101,101|105,105|108,111|118,119|122,122|128,128|135,150|152,153|164,173|176,176|200,201|203,216|225,226|228,228|240,240|246,249|259,259|264,266|271,274|280,286|290,292|294,294|297,302|313,313|333,335|346,346|348,351 Q:3,3|5,5|8,11|13,20|22,33|54,54|56,57|61,64|66,66|68,77|79,83|85,89|91,100|102,104|106,107|112,117|120,121|123,127|129,134|151,151|154,163|174,175|177,199|202,202|217,224|227,227|229,239|241,245|250,258|260,263|267,270|275,279|287,289|293,293|295,296|303,312|314,332|336,345|347,347|352,352 ???S?S??EEEE?SSGGGHHH-HHHHHTTHHHHT--------------------T?TT?--EEEE?S?HHHHHHHHHH?GGGTS?SEEEE-ETHHHHHHHH?TTS-SS????EEEEEE??BS?EEEEE?GGGGGG???-------------S??TTHHHHHHTS----------SS?EEEESSTTSHHHHHHHHHHHHTT??B--------------TTTBEEEE??G-GGHHHHHHTTS?SEEEE----ETTHHHHHH-HHTS?--EEEE----EGGGT-------BTT?--B?EE------EEEEHHHHHH?HHHHHHHHHHHHHHHHHHH--?GGGHHHHHHH-H----H 2I49|A PF13380.1_CoA_binding_2_seed 341 231 !Q:0,10|16,19|21,22|26,28|33,33|40,40|42,48|51,53|56,60|63,63|68,72|79,79|81,87|89,95|100,102|104,104|106,113|115,116|118,138|142,143|145,145|157,157|161,168|170,175|179,180|183,196|206,211|213,213|215,215|217,217|220,221|223,224 Q:11,15|20,20|23,25|29,32|34,39|41,41|49,50|54,55|61,62|64,67|73,78|80,80|88,88|96,99|103,103|105,105|114,114|117,117|139,141|144,144|146,156|158,160|169,169|176,178|181,182|197,205|212,212|214,214|216,216|218,219|222,222|225,230 ??---------EEEES??--S-?TTS---HHHH-HHHHHH-H-------HT-??EE-----EE?SSST-----TSEETT-E-------E-----??SSTT---T?S--------S??S---------------------EEE??S?STHHHHHHHHH-HHH--------T----??EEE??TT-----------???HHHHHHHHT------T-T?E-EE?-S??HHHHST 1IUK|A PF13382.1_Adenine_deam_C_seed 110 211 !Q:3,3|5,5|13,18|21,25|30,36|39,42|49,50|54,54|56,58|68,71|79,80|84,85|92,92|114,121|126,126|133,133|142,142|144,144|158,158|162,162|164,164|167,169|171,171|173,173|175,177|189,189|208,209 Q:0,2|4,4|6,12|19,20|26,29|37,38|43,48|51,53|55,55|59,67|72,78|81,83|86,91|93,113|122,125|127,132|134,141|143,143|145,157|159,161|163,163|165,166|170,170|172,172|174,174|178,188|190,207|210,210 SSS-S?EEEEEEE------EB-?---SSSB-???---TT--?-EEEEEE??SSS-S???EEEEEEESS???-SSEEEES??TTT??EEEEES?HHHHHHHHHHHHHTTSEEEEE--------ETTE-EEEEEE?TBTTTBBS-S?HHHHHHHHHHHHH-HHH-T-TS??-B-T-T---TBSGGGGGSTT?TTSSSEEEETTEEEETTT??E 3T81|A PF13384.1_HTH_23_seed 345 82 !Q:9,10|17,19|21,29|31,31|40,40|42,44|50,50|53,54|59,63|65,68|70,70|73,76 Q:0,8|11,16|20,20|30,30|32,39|41,41|45,49|51,52|55,58|64,64|69,69|71,72|77,81 HHHSHHHHH--HHHHHT---T-------??B?HHHHHHHH-T-??HHHHH-HH--HHHH-----H----H-TT----SEEEE 1ULY|A PF13385.1_Laminin_G_3_seed 726 787 !Q:1,1|3,8|10,10|12,13|15,18|21,30|32,34|36,38|40,55|57,62|64,92|95,101|104,127|129,130|136,137|139,139|142,164|166,168|172,176|179,216|218,221|224,225|227,243|247,247|249,251|253,273|275,280|283,286|289,289|291,302|305,305|307,308|310,320|323,325|329,332|334,334|336,365|369,378|381,387|390,422|424,427|429,430|432,432|438,438|440,441|445,455|458,459|461,479|481,487|490,493|496,496|498,504|506,508|511,518|522,524|526,535|537,539|541,620|622,625|627,635|638,639|642,645|647,665|667,670|673,700|702,714|716,716|719,741|743,749|751,755|757,761|763,763|771,776|778,781 Q:0,0|2,2|9,9|11,11|14,14|19,20|31,31|35,35|39,39|56,56|63,63|93,94|102,103|128,128|131,135|138,138|140,141|165,165|169,171|177,178|217,217|222,223|226,226|244,246|248,248|252,252|274,274|281,282|287,288|290,290|303,304|306,306|309,309|321,322|326,328|333,333|335,335|366,368|379,380|388,389|423,423|428,428|431,431|433,437|439,439|442,444|456,457|460,460|480,480|488,489|494,495|497,497|505,505|509,510|519,521|525,525|536,536|540,540|621,621|626,626|636,637|640,641|646,646|666,666|671,672|701,701|715,715|717,718|742,742|750,750|756,756|762,762|764,770|777,777|782,786 E-E------E-E--E----ES?--------?E---E---E?----------?---?T------T?-----------------?----------BS-------SE------------------------E--EEEEE--E-ES--------?-----?-?------S---SEE-----EE--------------------------------------E----ET--T-----------------TEE-E---E---------------------E------EE----GG-G------------TS-E--E-----------EE---EEE----E-E------------------------------ESS---------?EE-----?-SS-----------??-?------------------S----S-?E-EEEEE-E--EET-----------TT--T-------------------E-------EE----EE-E-------T---TE--------EEE---E----------E---E--?--????-----------------------------------------------------------------------B?---T---------TS--TT--?-E-------------------E----ES-------------------------??-T-------------T?TT-----?------------????-E-------E-----E-----E-EEEEEES------S-???HHHHH 2SLI|A PF13392.1_HNH_3_seed 226 75 !Q:11,15|17,20|22,25|27,27|29,39|46,46|48,49|51,54|56,58|60,61|68,68 Q:0,10|16,16|21,21|26,26|28,28|40,45|47,47|50,50|55,55|59,59|62,67|69,74 EEHHHHHHHHH----?T----T??--T-T-?---------EEEETT-S-?T----T???G--GGEEEE?HHHHHH 1U3E|M PF13393.1_tRNA-synt_His_seed 129 451 !Q:1,5|28,28|31,34|40,41|49,53|56,56|58,72|74,80|84,84|88,88|102,102|104,104|106,109|111,111|114,123|133,134|136,156|167,167|170,172|176,176|189,191|194,197|200,205|207,207|221,221|223,223|225,225|229,232|247,247|253,253|258,260|262,262|264,266|268,269|271,271|280,282|284,284|286,287|292,297|307,308|314,315|317,318|320,322|324,324|326,327|331,331|351,352|359,359|362,364|366,366|369,370|378,383|386,388|390,391|393,395|402,402|409,409|411,415|417,440 Q:0,0|6,27|29,30|35,39|42,48|54,55|57,57|73,73|81,83|85,87|89,101|103,103|105,105|110,110|112,113|124,132|135,135|157,166|168,169|173,175|177,188|192,193|198,199|206,206|208,220|222,222|224,224|226,228|233,246|248,252|254,257|261,261|263,263|267,267|270,270|272,279|283,283|285,285|288,291|298,306|309,313|316,316|319,319|323,323|325,325|328,330|332,350|353,358|360,361|365,365|367,368|371,377|384,385|389,389|392,392|396,401|403,408|410,410|416,416|441,450 T?????TTHHHHHHHHHHHHHHHHHHTT?EE????SEEEH--HHHHTTS----?TT-S--?-?------?-??B?-??-?-SSS?EEE?SSSHHHHHHHHHH-H-H----H-TT?------???EEEEEEEEE--E?????--????????--??--EEEEEEEEEE?SS???HHH-HHHHHHHHHHHH---HH----HT-?---?S?EEEEEETTHHHHH-H-H-HTT--??HHHHHHHHHHHHHT?HHHHH-HHHH---H-H?--S??S?HHHHHHHB???S-S-?TTSB-----?HHHHHHHHH--HHHTT-?S?-H---H-H--HHH-HHHHHHHHHHHHHHHHHHT??TTTEEE?TT???S?TT??SEEEEEE?-----TT--?S--S--?SEEEEE?TTTTGG-G-----T--?----------??-------??EEEEEEHHHH 3RAC|A PF13394.1_Fer4_14_seed 151 195 !Q:3,4|6,7|9,22|24,39|41,41|43,48|52,53|55,70|72,72|77,77|86,86|91,97|105,107|114,114|116,116|119,120|138,146|149,149|153,170|179,184|186,186|193,195 Q:0,2|5,5|8,8|23,23|40,40|42,42|49,51|54,54|71,71|73,76|78,85|87,90|98,104|108,113|115,115|117,118|121,137|147,148|150,152|171,178|185,185|187,192 EEE--S??S?-----------??T----------------T?S-----?GGG??S----------------S?SEEE?HHHHHHHH-GGGH-------HHHHHHT--?EEEEEE-S?GG--GGHHHHHHHHHHHHTTT-------??EE-EEE?????--------?--??HHHHHHHH------T?SEEEEE??- 2FB3|A PF13397.1_DUF4109_seed 79 121 !Q:1,5|8,17|20,21|25,27|36,36|39,39|41,41|50,52|54,59|64,64|66,66|75,77|80,82|87,120 Q:0,0|6,7|18,19|22,24|28,35|37,38|40,40|42,49|53,53|60,63|65,65|67,74|78,79|83,86 S?????TT?------???SS??GGG???SEEEEEEE?TT-S?EEEEEEET---T???--?SEEE?T-TSSEEEEE--?SS--?SSSS-??????--------------------------- 2M6O|A PF13401.1_AAA_22_seed 168 254 !Q:2,7|9,13|15,20|23,23|25,25|48,74|77,78|90,97|103,103|113,116|118,140|142,144|150,150|161,161|163,178|190,190|192,195|199,201|209,210|214,221|227,240|246,247|249,249 Q:0,1|8,8|14,14|21,22|24,24|26,47|75,76|79,89|98,102|104,112|117,117|141,141|145,149|151,160|162,162|179,189|191,191|196,198|202,208|211,213|222,226|241,245|248,248|250,253 TS------S?????E------EE?B?TTSSHHHHHHHHHHHHHHHHHH---------------------------HT??EEEEEEETTTS?-------SHHHH-HHHHHHHHS????S-----------------------S???HHHHH-HHHHHHHTTS?S----------------EEEEEEETTTH-H----HHS---TTHHHHH--HHH--------HHGGG??------??????EEEEE?-S?STTS 1FNN|A PF13402.1_M60-like_seed 67 387 !Q:0,2|4,4|11,11|14,15|21,26|29,30|37,37|44,61|66,69|71,71|78,80|83,83|90,97|100,106|115,115|118,119|126,127|129,129|140,140|142,142|144,144|149,149|157,158|166,167|169,170|189,189|194,194|198,199|204,205|207,208|210,216|224,228|243,248|253,253|255,255|261,261|263,263|275,275|278,278|281,282|284,286|288,289|307,313|317,326|332,336|345,345|352,370|386,386 Q:3,3|5,10|12,13|16,20|27,28|31,36|38,43|62,65|70,70|72,77|81,82|84,89|98,99|107,114|116,117|120,125|128,128|130,139|141,141|143,143|145,148|150,156|159,165|168,168|171,188|190,193|195,197|200,203|206,206|209,209|217,223|229,242|249,252|254,254|256,260|262,262|264,274|276,277|279,280|283,283|287,287|290,306|314,316|327,331|337,344|346,351|371,385 ???E-EEEEEE?TT??EEEEE-----?SS??EEEEES?TTTSSS----------------??EEEE----E?SEEEEE??-TT?EEEEEE-----???SS?-----?EEEEEEES?EE??EEETTT??H-HHHHHHHHHS?S?S?EEEE?SSEEEEE-?HHHHHHH??S--SSSHHHHHHHHHHHHHHH-HHTT?BSS??GGGB??S??E-------EEEEETT??--?SEEEETTEEEEETT----??HHHH?H-HHHHH-H?HHHHHHHHHHH?BG-GG??T---T-?TTTTHHHHHHHHHHHTT---?-??HHH----------HTTHH-----HHHHTTTT?TTHHHH?-----------------?HHHHHHHHHHHHHHH? 4FCA|A PF13403.1_Hint_2_seed 194 213 !Q:0,1|6,6|10,10|14,14|21,22|25,25|30,36|39,41|51,51|54,55|58,63|66,66|73,74|76,78|82,83|86,86|89,96|98,108|115,125|133,138|141,141|145,146|148,150|152,152|155,158|160,161|172,174|176,176|178,180|183,183|194,195|198,208 Q:2,5|7,9|11,13|15,20|23,24|26,29|37,38|42,50|52,53|56,57|64,65|67,72|75,75|79,81|84,85|87,88|97,97|109,114|126,132|139,140|142,144|147,147|151,151|153,154|159,159|162,171|175,175|177,177|181,182|184,193|196,197|209,212 ??EETT?EEE?SSS-EEEGGG??TT?EEET??-----EE---EEEEEEEEE-EE--EE------EE-EEEEET--T---EEE--EE?TT?-------E-----------EEETTT-----------EEEEGGG?----?TT?EEE--B---T-TS--?-E--EEEEEEEEEE---E-E---EE-EEEEEEEESS??EE-----------EETT 2LWY|A PF13404.1_HTH_AsnC-type_seed 347 48 !Q:0,2|15,18|21,22|29,30|35,35 Q:3,14|19,20|23,28|31,34|36,47 ?-?HHHHHHHHHHHH?---TT??HHHHHH--HHTS?HHHHHHHHHHHH 2VBW|A PF13405.1_EF-hand_6_seed 793 61 !Q:3,4|11,11|13,13|16,20|22,24|26,27|29,29|33,33|36,39|43,56|58,60 Q:0,2|5,10|12,12|14,15|21,21|25,25|28,28|30,32|34,35|40,42|57,57 HHH--HHHHHH-S-SS---??S--?B?-H-HHH-HH----HTT--------------S-?? 1BR1|B PF13406.1_SLT_2_seed 176 458 !Q:0,3|17,19|27,30|34,49|57,63|65,85|94,94|96,97|109,109|124,126|143,148|150,153|166,166|168,196|204,207|223,225|227,243|246,247|250,250|253,254|261,261|269,274|280,282|286,288|301,301|305,305|307,308|311,314|322,334|342,345|349,351|355,366|371,371|377,396|404,404|408,410|416,424|427,427|432,432|436,436|444,445 Q:4,16|20,26|31,33|50,56|64,64|86,93|95,95|98,108|110,123|127,142|149,149|154,165|167,167|197,203|208,222|226,226|244,245|248,249|251,252|255,260|262,268|275,279|283,285|289,300|302,304|306,306|309,310|315,321|335,341|346,348|352,354|367,370|372,376|397,403|405,407|411,415|425,426|428,431|433,435|437,443|446,457 ????HHHHHHHHHHHHH???HHHHHHH----HHT?-???-----------HHHHHHH-------T???----???-?--?------HHHHHHHH-S?-HHHHHHHHHHH-HHTHHHHHHHHHHH???HHHHHHHHHHHHTTTT-???--S----EEHHHHHHHHHH-H--?--------------------------GGGHHHH----HHHHHHHHHHHHHHT-??G-----------------GG-?EE?TT??BTTTTB?HHHHHHH??---?SSSSS???TTT?--HHHHHHHHHHHH-HHT-T??TT-???EEEEEES-------------SGGGGGG??--SSS???EEH------------HHHH-HTTEE???------------?--??SSSEEEE-EEE---EETTE---------EE-EEEE?HHH-HHHHHHS??HHHHHHHHHHHH 1D0K|A PF13407.1_Peripla_BP_4_seed 173 528 !Q:2,6|11,12|17,17|22,25|37,37|40,40|45,49|51,57|59,61|64,64|66,66|77,77|82,90|92,93|97,98|100,101|105,106|111,111|117,117|123,126|130,137|141,152|156,157|160,169|174,174|179,181|187,218|228,240|247,250|252,253|256,257|262,264|267,270|275,275|279,283|287,305|307,307|314,342|346,346|348,348|350,350|358,358|365,367|369,369|371,388|391,391|394,395|403,413|415,418|426,426|429,435|437,448|454,455|460,460|464,476|481,484|486,488|492,493|496,498|501,502|512,512|515,516|519,524|526,527 Q:0,1|7,10|13,16|18,21|26,36|38,39|41,44|50,50|58,58|62,63|65,65|67,76|78,81|91,91|94,96|99,99|102,104|107,110|112,116|118,122|127,129|138,140|153,155|158,159|170,173|175,178|182,186|219,227|241,246|251,251|254,255|258,261|265,266|271,274|276,278|284,286|306,306|308,313|343,345|347,347|349,349|351,357|359,364|368,368|370,370|389,390|392,393|396,402|414,414|419,425|427,428|436,436|449,453|456,459|461,463|477,480|485,485|489,491|494,495|499,500|503,511|513,514|517,518|525,525 EE-----EEES-?SSSH-HHHH----HHHHHHHHHHH-HT?EEEE-----E-------E--?TT?H-HHHHHHHHHH-HHTT--------?S--EEE--E??SST--TTTH-HHHHH-HHHTT?-?-EEE--------ESS?----------?SSS??SE----------EEEE?HHHH---HHHHH--------------------------------HHHHHHTTT?------------EEEEEE----E??TT-?HHHH---HH----HHHH-HHH-----HTT------------------?T-TEEEEE-----------------------------EEE?T-T?HHHHHHH-HHHHHH---H?S?-------?--------?EE-EE--SSHHHHH-----------H----HHHHHHH-TT?--???-E------------EEEEE??HHHH-HHH-------------HTTS??--E---EEE??HH---HH--HHHHHHHHH-HH--HT------T?? 3D02|A PF13408.1_Zn_ribbon_recom_seed 726 198 !Q:2,3|5,6|8,9|11,12|18,24|27,34|36,42|44,48|51,60|62,66|68,71|76,79|85,102|108,109|111,114|117,117|119,122|125,127|129,131|133,133|137,172|176,176|181,183|187,189|193,195 Q:0,1|4,4|7,7|10,10|13,17|25,26|35,35|43,43|49,50|61,61|67,67|72,75|80,84|103,107|110,110|115,116|118,118|123,124|128,128|132,132|134,136|173,175|177,180|184,186|190,192|196,197 TT--T--T--T--EEETT-------TS----?---B-------E-----EE----------E-----E----EEEE----ETTEE------------------EEEEE--E----EE-G----GG---T--?T-TTS?----------------?-----???--?------?EEH-HHHH---HHH---HHH---HH 4KIS|A PF13409.1_GST_N_2_seed 315 308 !Q:1,2|6,7|14,14|19,23|25,27|30,30|33,36|39,40|42,42|44,64|69,70|76,93|95,98|100,132|135,138|142,143|154,154|156,156|158,166|168,229|231,231|236,264|266,267|272,283|287,290|292,295|301,301|304,304 Q:0,0|3,5|8,13|15,18|24,24|28,29|31,32|37,38|41,41|43,43|65,68|71,75|94,94|99,99|133,134|139,141|144,153|155,155|157,157|167,167|230,230|232,235|265,265|268,271|284,286|291,291|296,300|302,303|305,307 T?-HHH--HHHHHH-HHHT-----T?--TT-TE----EE--E-E----------------?----EEEE--ETTEE------------------E????S---------------------------------TT????TTT??SBHHHHHHHH?T-T-??------B--?--?--------------------------------------------------?-----S?EEEE-----------------------------T--TTTE------------EEE?--?H----HHHHH-HH-HHT 2NTO|A PF13410.1_GST_C_2_seed 279 263 !Q:3,4|8,55|57,57|61,65|72,73|76,83|86,86|88,88|91,129|133,143|147,147|150,156|158,159|163,164|168,168|170,172|174,177|180,182|184,184|186,186|188,193|197,201|204,206|208,208|211,231|234,234|236,242|244,247|249,249|251,252|260,260 Q:0,2|5,7|56,56|58,60|66,71|74,75|84,85|87,87|89,90|130,132|144,146|148,149|157,157|160,162|165,167|169,169|173,173|178,179|183,183|185,185|187,187|194,196|202,203|207,207|209,210|232,233|235,235|243,243|248,248|250,250|253,259|261,262 HHH--HHH------------------------------------------------H-HHH-----HHHHHH--HH--------HH-H-TT---------------------------------------SSS-----------BTT-BS-------S??HHH--HHH-H---H----HH---H-T-I------III-----IT---T-TT?------------------??SS?G-------G----G-S--HHHHHHH-HH 1N2A|A PF13411.1_MerR_1_seed 214 86 !Q:1,1|10,20|33,35|37,38|41,44|48,50|54,54|70,70|73,74|84,84 Q:0,0|2,9|21,32|36,36|39,40|45,47|51,53|55,69|71,72|75,83|85,85 B?HHHHHHHH??--------?HHHHHHHHHTTS---S??EE---?TTT??-EEB?HHHHHHHHHHHHHHH-TT??HHHHHHHHH?T 1Q07|A PF13412.1_HTH_24_seed 608 54 !Q:0,1|9,9|15,17|20,22|32,35 Q:2,8|10,14|18,19|23,31|36,53 ??SHHHHHH-HHHHH--?SS-??TTGGGTSSS--??TTTSSSTHHHHHHHTSEE 3K0L|A PF13413.1_HTH_25_seed 195 80 !Q:10,11|20,22|33,33|36,36|40,43|46,50|65,69|71,73|75,77 Q:0,9|12,19|23,32|34,35|37,39|44,45|51,64|70,70|74,74|78,79 HHHHHHHHTT??HHHHHHHH???HHHHHHHHHT?HH-HHH----SS----?HHHHHHHHHHHHTT-?--?H---H---HH 3FYM|A PF13414.1_TPR_11_seed 458 181 !Q:1,5|7,8|10,11|13,14|16,16|23,23|26,26|28,31|33,33|35,39|51,51|53,55|57,59|61,74|76,76|78,85|88,97|100,100|103,104|106,108|112,112|115,116|119,122|124,135|138,141|143,143|145,148|152,153|155,156|158,158|160,160|162,165|167,167|169,174|176,179 Q:0,0|6,6|9,9|12,12|15,15|17,22|24,25|27,27|32,32|34,34|40,50|52,52|56,56|60,60|75,75|77,77|86,87|98,99|101,102|105,105|109,111|113,114|117,118|123,123|136,137|142,142|144,144|149,151|154,154|157,157|159,159|161,161|166,166|168,168|175,175|180,180 T-?---H--H--H--H-HHHHHH-HH-H----T-T--?--HHHHHHHHHHH-H---H---H------?-------T-T---?----HH----------HH-HH--H---HHH-HH--HT----T---------?--HH----H-H----HHH--H--H-H-H----H-H------H-?--T 2FI7|A PF13415.1_Kelch_3_seed 122 111 !Q:2,3|9,12|14,23|25,26|30,36|38,38|40,41|44,47|50,53|57,64|68,73|76,93|96,102|105,105 Q:0,1|4,8|13,13|24,24|27,29|37,37|39,39|42,43|48,49|54,56|65,67|74,75|94,95|103,104|106,110 TT--EEEEE??--B?---------S--SSB?----??E-E--EE----ET----TTT--------EEE------EE--------??---?----SS-----??BS?EEEEE 1U6D|X PF13416.1_SBP_bac_8_seed 141 985 !Q:6,6|8,11|13,17|19,24|27,33|35,35|37,38|41,41|45,50|52,53|55,55|57,58|61,61|65,67|71,74|77,78|80,82|84,92|94,96|98,100|102,105|109,110|114,115|117,117|123,126|129,131|134,143|145,146|148,160|163,165|167,167|172,212|214,215|221,221|229,238|242,255|257,257|262,262|264,264|266,268|270,285|289,289|294,302|304,304|308,319|322,338|341,341|343,349|352,357|359,365|374,380|382,400|402,407|409,410|412,437|441,441|444,451|453,460|462,477|479,485|488,498|501,501|503,503|514,523|526,527|534,534|536,541|543,551|555,578|582,582|587,587|590,592|595,598|600,601|603,604|606,619|622,639|641,654|657,658|662,667|670,671|673,674|680,685|687,691|693,696|699,701|704,706|708,708|711,728|731,741|743,748|750,757|766,774|776,801|803,813|818,818|821,832|834,834|837,841|844,844|846,848|850,855|858,859|861,864|867,870|872,874|876,877|880,882|885,886|893,893|895,896|900,900|902,902|904,904|911,914|916,919|923,926|929,934|936,936|938,938|940,940|942,943|945,946|948,954|963,969|971,977|980,981 Q:0,5|7,7|12,12|18,18|25,26|34,34|36,36|39,40|42,44|51,51|54,54|56,56|59,60|62,64|68,70|75,76|79,79|83,83|93,93|97,97|101,101|106,108|111,113|116,116|118,122|127,128|132,133|144,144|147,147|161,162|166,166|168,171|213,213|216,220|222,228|239,241|256,256|258,261|263,263|265,265|269,269|286,288|290,293|303,303|305,307|320,321|339,340|342,342|350,351|358,358|366,373|381,381|401,401|408,408|411,411|438,440|442,443|452,452|461,461|478,478|486,487|499,500|502,502|504,513|524,525|528,533|535,535|542,542|552,554|579,581|583,586|588,589|593,594|599,599|602,602|605,605|620,621|640,640|655,656|659,661|668,669|672,672|675,679|686,686|692,692|697,698|702,703|707,707|709,710|729,730|742,742|749,749|758,765|775,775|802,802|814,817|819,820|833,833|835,836|842,843|845,845|849,849|856,857|860,860|865,866|871,871|875,875|878,879|883,884|887,892|894,894|897,899|901,901|903,903|905,910|915,915|920,922|927,928|935,935|937,937|939,939|941,941|944,944|947,947|955,962|970,970|978,979|982,984 HHHHHH-H----H-----H----?-TT-------E-E--EE-EEE--?-??S--S-S--HH-HHH---HHH----HH--H---T--?--?--?S---E---E----EEE?-HHH--H-HHHHH----TT---SB?--------?G--G-------------GS---T-THHH-----------------------------------------H--HHHTT?HHHHHHT-------??-TTS--------???--?E-EEEE-E-E?--E----------------EEE?HHHH---------H-HTT-----------?SS-----------??---?BH-H-------HH------H-------HHHHHHHH-------H--?----------------T------T?-E--------------------------EEE?GG--------G--------G----?---?-----?-G-------GG-----------GG-G-THHHHHHHHT----------TS??SEETTE-E-?--??H---------HHH------------------------HHH-HHHH-HH---HH----H--T--T-----?--------EE----------------?-S----------?--?SS--HHH------HT--S--EEEEE------E----?T----TH---HH---H-HH------------------HH--?--------T------T-??-----BTTTBEEE???------B---------?----------------G-----------GGTT?SS??----------E-EE-----EE-E---E------EE--E----BT----T---S?-HH---HH--HHHHHH-H--HHH-T-T-SHHHHH----H----HHH----HH??--?-B-S?S?T--T--T------?GGGHHHHH-------H?------HH--HHH 3G7W|A PF13417.1_GST_N_3_seed 216 194 !Q:2,3|5,7|10,11|15,16|22,22|29,29|34,37|39,43|46,47|49,63|65,71|74,78|80,90|92,93|95,96|98,105|109,115|118,122|124,125|127,132|134,136|138,141|144,151|154,158|161,161|163,163|167,167|170,170|172,174|180,188|190,193 Q:0,1|4,4|8,9|12,14|17,21|23,28|30,33|38,38|44,45|48,48|64,64|72,73|79,79|91,91|94,94|97,97|106,108|116,117|123,123|126,126|133,133|137,137|142,143|152,153|159,160|162,162|164,166|168,169|171,171|175,179|189,189 EE--E--?SS-?HHH--HHHHH-HHHHHT?GGGE----E-----EE--E-----?-----??--B-------TT-----B---?------?H--H--H--------HHH--?----TT?---?S??E------E-?-T----TS?-------EE?----SH-H-HHH-HH-H---TTSSS---------S?--? 2NTO|A PF13418.1_Kelch_4_seed 84 105 !Q:0,1|4,4|6,6|10,10|12,13|17,18|20,21|23,23|28,30|35,35|37,45|47,48|50,51|53,54|56,57|59,62|65,66|69,70|72,73|75,76|78,85|87,98|100,102 Q:2,3|5,5|7,9|11,11|14,16|19,19|22,22|24,27|31,34|36,36|46,46|49,49|52,52|55,55|58,58|63,64|67,68|71,71|74,74|77,77|86,86|99,99|103,104 ??BS?E-EEE-E--TTT--T--E-EEEE?-?BSST-T--------?B??B?-E--E--E----ET--TT--T--E--E--------E??-------?--B?--SB 1U6D|X PF13419.1_HAD_2_seed 169 417 !Q:3,4|9,10|12,17|21,28|35,41|43,46|48,57|59,61|66,72|74,91|95,99|103,109|111,117|119,125|130,131|133,133|136,137|140,141|143,143|148,158|162,162|165,169|173,176|178,178|183,203|205,208|210,210|217,228|232,234|237,243|245,246|249,249|253,253|259,259|261,263|265,267|272,272|276,276|280,284|286,287|290,290|293,293|295,297|302,303|305,309|311,318|320,322|326,326|329,331|333,334|336,337|340,340|342,347|354,354|364,365|369,371|373,375|378,381|383,386|392,392|398,399|402,402|405,405|409,409|412,412|414,414 Q:0,2|5,8|11,11|18,20|29,34|42,42|47,47|58,58|62,65|73,73|92,94|100,102|110,110|118,118|126,129|132,132|134,135|138,139|142,142|144,147|159,161|163,164|170,172|177,177|179,182|204,204|209,209|211,216|229,231|235,236|244,244|247,248|250,252|254,258|260,260|264,264|268,271|273,275|277,279|285,285|288,289|291,292|294,294|298,301|304,304|310,310|319,319|323,325|327,328|332,332|335,335|338,339|341,341|348,353|355,363|366,368|372,372|376,377|382,382|387,391|393,397|400,401|403,404|406,408|410,411|413,413|415,416 EEE??BTTT--B---?--HHH--------HHHHHT-------H----H----------H---HHHH-------T?--?-----------??-HHH-----HHH-------H-------H-------HHHH--G-GG??SS??S?HHHH-----------HHH-HH-----HHH----H-HHTT---------------???--?H----H-HHHHHH------------TGG---GG?--?---B-?TT-HHH-HHHHH-H---H---HSEE-EEE-ESS--?--H--HH-HH-H---HHTT--T----?S?------?S---EEE-EH---H--H--HT-S--?---TTSHHH-HHHHHHHHH--HTT?-?G---GG----E----EEEES?TTTTH--HH-HH-HHT?EE-E-EE 2HDO|A PF13420.1_Acetyltransf_4_seed 21 216 !Q:3,4|9,9|17,18|21,25|28,30|32,32|34,38|45,46|52,52|59,68|71,72|81,82|85,85|94,95|97,101|104,104|114,114|119,120|122,122|125,125|132,134|141,141|145,145|150,151|158,158|162,169|171,174|176,183|193,193|208,208 Q:0,2|5,8|10,16|19,20|26,27|31,31|33,33|39,44|47,51|53,58|69,70|73,80|83,84|86,93|96,96|102,103|105,113|115,118|121,121|123,124|126,131|135,140|142,144|146,149|152,157|159,161|170,170|175,175|184,192|194,207|209,215 EEE??GGGH-HHHHHHH--HT-?-??TT--?H-H-----HHHHHH??HHHHH-HHHSTT-----?----TT--EEEEEEES--SS?EEEEEEEE--E?---?ST-TTTTEEEEE-EEEE--G-GG?HHHHHH---HHHHHH-HHH-HHTT??EEEEEE-ETT-------?H----H--------HHHHHHTTT?EEEEEEEEEEEETT-EEEEEEE 3R9G|A PF13423.1_UCH_1_seed 21 852 !Q:0,0|3,6|9,10|23,23|36,36|40,52|54,55|58,58|72,72|74,76|78,79|84,85|91,91|98,102|104,115|122,155|159,161|175,176|178,187|190,215|219,219|224,290|302,303|311,311|321,323|327,333|336,337|340,344|348,348|352,353|355,362|366,405|416,416|419,419|423,423|427,427|437,438|440,593|603,604|612,613|617,619|623,625|627,628|631,689|693,694|697,698|700,701|705,735|737,744|746,755|758,760|770,771|774,776|779,779|781,781|783,783|792,798|801,818|821,838|845,848 Q:1,2|7,8|11,22|24,35|37,39|53,53|56,57|59,71|73,73|77,77|80,83|86,90|92,97|103,103|116,121|156,158|162,174|177,177|188,189|216,218|220,223|291,301|304,310|312,320|324,326|334,335|338,339|345,347|349,351|354,354|363,365|406,415|417,418|420,422|424,426|428,436|439,439|594,602|605,611|614,616|620,622|626,626|629,630|690,692|695,696|699,699|702,704|736,736|745,745|756,757|761,769|772,773|777,778|780,780|782,782|784,791|799,800|819,820|839,844|849,851 ?EE??-?SS-?HHHHHHHHHHHT-STTHHHHHHTTG-GGG-------------T??SS?TTSHHHHHHHHHH-H---S?-EEEE??HHHHH-HHHHHB-----G------------GGTSSS-------------------------------???HHH---HHHHHHHHHHHHT??S---------?SS?????------------------???TTS?HHHH-------------------------------------------------------------------HHHHHHHHHHH??SHHHHHH?EEEEEEEEE---TTT??-----EE--EE??---EES?EEE??S?-------SSE----------------------------------------EEHHHHHHHH-TS?EEE?GGG?EEETTTTEE--E?---------------------------------------------------------------------------------------------------------------------------------------------------------EEEEEEEEE??SEEEEEE??EEE?--SSS---E--EE???--------------------------------------------------------EEE??SS-?B??GGG-------------------------------B-------?S--------??TT???BEEEEEEEE--ES?--TT-T?E-EEEEEEET-------TT------------------TE------------------EEEEET----TEE 3N3K|A PF13424.1_TPR_12_seed 266 132 !Q:0,0|2,4|6,8|10,12|14,17|19,19|21,21|23,24|26,28|31,31|33,33|38,38|42,42|57,57|61,61|63,64|66,69|71,73|75,78|80,80|83,83|85,85|88,89|91,91|101,101|104,108|110,111|114,114|127,129 Q:1,1|5,5|9,9|13,13|18,18|20,20|22,22|25,25|29,30|32,32|34,37|39,41|43,56|58,60|62,62|65,65|70,70|74,74|79,79|81,82|84,84|86,87|90,90|92,100|102,103|109,109|112,113|115,126|130,131 ?H---H---H---H----H-H-H--H---HH-H-HHHH-TTT?HHHHHHHHHHHHHH-HHH-H--H--?-T---T--?-H-HH-H-HH--H-HHHHHHHHT-TT--?--H--HH-HHHHHHHHHHHH---HH 4HOU|A PF13426.1_PAS_9_seed 245 367 !Q:0,0|3,5|8,9|12,12|15,16|20,36|41,41|45,47|52,70|72,72|74,78|81,82|84,85|87,88|90,107|109,109|111,113|115,116|118,151|154,174|176,176|178,179|181,181|183,188|191,201|205,206|209,209|211,224|227,236|238,242|244,244|246,247|249,249|253,255|257,263|265,265|267,289|291,295|297,301|303,304|314,324|327,327|329,330|332,333|335,336|338,345|348,348|351,352|356,359|361,364 Q:1,2|6,7|10,11|13,14|17,19|37,40|42,44|48,51|71,71|73,73|79,80|83,83|86,86|89,89|108,108|110,110|114,114|117,117|152,153|175,175|177,177|180,180|182,182|189,190|202,204|207,208|210,210|225,226|237,237|243,243|245,245|248,248|250,252|256,256|264,264|266,266|290,290|296,296|302,302|305,313|325,326|328,328|331,331|334,334|337,337|346,347|349,350|353,355|360,360|365,366 ?SE---EE--EE?TT--STT---------------??EEEE?HHH---HHHH---??--?-----------G-G-----GT--T--T--S-?----------------G-G---G--G?----------------------------?----TT-----?-----------?---H-H--H-H------HH-----------HHH--HH-H--------------TT?----?----E-----E-E--E-EEE---E---?---T-T-----------------------S----?E-----E--EEEEEEEEE-----------EE-T--T--E--E--------EE-EE--EEE----E---?HH 3F1N|A PF13428.1_TPR_14_seed 819 115 !Q:1,1|3,3|5,6|8,9|11,12|14,15|17,17|19,20|22,22|24,25|27,28|30,31|33,34|36,37|39,44|46,47|49,49|51,53|57,57|59,59|63,64|66,68|70,71|73,76|78,82|84,93|95,96|98,100|103,105|109,109|112,113 Q:0,0|2,2|4,4|7,7|10,10|13,13|16,16|18,18|21,21|23,23|26,26|29,29|32,32|35,35|38,38|45,45|48,48|50,50|54,56|58,58|60,62|65,65|69,69|72,72|77,77|83,83|94,94|97,97|101,102|106,108|110,111|114,114 H-H-H--H--H--H--H-H--H-H--H--H--H--H--T--?---H--H-H---HHH-H-HHH--H---H--H----H--?--S---?--?---H--H---HH---HHH-HH--H 3K9I|A PF13429.1_TPR_15_seed 27 320 !Q:0,7|12,13|15,16|19,19|21,21|24,29|34,34|52,52|56,60|64,68|78,78|83,86|93,103|105,107|111,111|114,114|123,132|142,142|155,156|159,160|167,168|172,172|174,175|177,177|193,193|208,211|219,228|231,236|238,261|267,267|278,278|286,286|299,319 Q:8,11|14,14|17,18|20,20|22,23|30,33|35,51|53,55|61,63|69,77|79,82|87,92|104,104|108,110|112,113|115,122|133,141|143,154|157,158|161,166|169,171|173,173|176,176|178,192|194,207|212,218|229,230|237,237|262,266|268,277|279,285|287,298 ??---?-?HHHH--H--HH-H-HH------HHTT?HHHHHHHHHHHHTTSSS?HHH-----HHH-----HHHHHHHTT?HHHH----HHHHHH-----------H---HHH?TT?HHHHHHHH----------HHHHHHHHT?SSHHHHHHHHHH--HH--HHHHHH--HHH?T--T?HHHHHHHHHHHHHTT?HHHHHHHHHHHHHH???-HHHHHHH----------HH------H------------------------HHHHT?HHHHHHHHHH-HHHHSTT?HHHHHHHHHHHT????????--??????????? 2PL2|A PF13431.1_TPR_17_seed 374 68 !Q:8,12|15,19|25,26|30,31|33,33|35,35|37,37|39,47|50,50|52,57|60,62|65,65 Q:0,7|13,14|20,24|27,29|32,32|34,34|36,36|38,38|48,49|51,51|58,59|63,64|66,67 HHHHHHHH--?--TT-?---HHHHH--HHH--H-H-H-H---------HT-T---?--HH---HH-HH 3KD7|A PF13432.1_TPR_16_seed 121 85 !Q:11,12|21,21|28,31|34,38|51,51|54,56|58,58|64,64|72,77|80,80|83,83 Q:0,10|13,20|22,27|32,33|39,50|52,53|57,57|59,63|65,71|78,79|81,82|84,84 HHHHHHHHHTT?-HHHHHHHH-HHHHHH?---TT----?HHHHHHHHHHHH-HT---T?HHHHH-HHHHHHH------HH?TT?H 2PL2|A PF13433.1_Peripla_BP_5_seed 64 491 !Q:0,1|6,7|35,42|46,49|51,52|54,57|63,64|67,67|81,81|84,86|91,92|109,109|113,114|116,116|118,127|133,134|136,137|154,163|186,186|188,188|193,194|196,198|200,201|203,204|207,208|213,213|216,217|219,221|223,224|226,227|237,240|243,246|248,252|254,257|263,264|279,283|285,290|292,292|294,299|305,306|314,317|320,323|328,328|334,335|338,338|351,351|355,356|358,367|369,369|371,376|382,382|398,401|403,403|405,408|410,412|420,420|423,428|432,434|439,439|441,441|443,443|445,445|447,447|451,451|455,456|462,462|466,466|469,470|475,475|478,478|480,482|485,486 Q:2,5|8,34|43,45|50,50|53,53|58,62|65,66|68,80|82,83|87,90|93,108|110,112|115,115|117,117|128,132|135,135|138,153|164,185|187,187|189,192|195,195|199,199|202,202|205,206|209,212|214,215|218,218|222,222|225,225|228,236|241,242|247,247|253,253|258,262|265,278|284,284|291,291|293,293|300,304|307,313|318,319|324,327|329,333|336,337|339,350|352,354|357,357|368,368|370,370|377,381|383,397|402,402|404,404|409,409|413,419|421,422|429,431|435,438|440,440|442,442|444,444|446,446|448,450|452,454|457,461|463,465|467,468|471,474|476,477|479,479|483,484|487,490 --EEEE??SSSTTHHHHHHHHHHHHHHHHHHHTTT--------TBT----T--B--??EEEEE??TT?HHHHHHHHHHHHH-TT???EEEE??SHHHHHHHHHHHHHTT?EEE--E?S?????--???TTEEE?-S??GGGTHHHHHHHHHTTT?---------SEEEEEEESSHHHHHHHHHHHH-H-HHHT--T?--E--E--EE--EEEE?SS??H---H--H--HHHHHHHHH----HH----T----?S----EEEEE??THHHHHHHHHHHHH-----H-----?S-S?-?-??EEESS??HHHHTTS---?HH----HHTT?EEEES??TT?SSHHHHHHHHHH-HTT--S--------?-T-T?--???HHHHH-HHHHHHHHHHHHHHH----T-S?--?H---HHHHHHH-TT?----?EEE---TTEE-E-E-E?T-TTS?EEB??EEEEE?TTS?EE--EEEE?SS?B???SS??GGGS 4EY3|A PF13434.1_K_oxygenase_seed 69 428 !Q:0,0|8,9|27,29|31,36|43,43|46,47|53,54|57,57|59,59|62,62|72,72|75,75|87,87|89,91|99,100|102,103|119,119|121,121|124,125|140,142|144,146|148,148|151,153|157,158|166,167|171,174|177,179|189,193|196,198|201,201|207,209|211,211|219,219|222,222|227,240|247,248|263,265|267,268|270,272|279,279|284,285|287,290|296,296|298,298|311,311|313,313|330,330|332,332|346,346|348,348|352,366|382,384|386,389|391,393|404,404|406,408|410,411|422,424|427,427 Q:1,7|10,26|30,30|37,42|44,45|48,52|55,56|58,58|60,61|63,71|73,74|76,86|88,88|92,98|101,101|104,118|120,120|122,123|126,139|143,143|147,147|149,150|154,156|159,165|168,170|175,176|180,188|194,195|199,200|202,206|210,210|212,218|220,221|223,226|241,246|249,262|266,266|269,269|273,278|280,283|286,286|291,295|297,297|299,310|312,312|314,329|331,331|333,345|347,347|349,351|367,381|385,385|390,390|394,403|405,405|409,409|412,421|425,426 ?EESEEEE??SHHHHHHHHHHHHHHHH---H?--???EEEEES?SS??SSGGG??SS?B?SS?TTSSSSTTT?TT?TTSHHHHHHHT-T--?HHHHHHH??S??BHHHHHHHHHHHHTT?T-TT--EEESEEEEEEEEEE---E---T-TE---EEE--EEEEEEE--TTS---?EE---EEEESEEEE???-?EE???GG-GGGGT---T?TTEEEGG-GH-HHHH????----??????EEEEEE??SHHHHHHHHHHHHH--?T--T---EEEEEE?SSSS??B????HHHHG-G-GSHHHHHHHHHS?H-HHHHHHHHHTGGGTSS?B?HHHHHHHHHHHHH-H-HHH--?-----??---?-SEEETTEEEEEEEEE---T----T---EEEEEEEETT-T?-?E--EEEEESEEEE???EE? 4A9W|A PF13435.1_Cytochrome_C554_seed 93 243 !Q:3,3|9,10|13,13|19,23|26,26|30,32|36,36|38,42|46,48|52,52|57,70|72,72|74,74|76,77|81,82|84,85|90,90|95,95|98,102|104,107|110,116|119,131|133,145|149,150|156,160|163,169|171,171|173,173|176,176|179,190|192,192|195,221|229,230|232,233 Q:0,2|4,8|11,12|14,18|24,25|27,29|33,35|37,37|43,45|49,51|53,56|71,71|73,73|75,75|78,80|83,83|86,89|91,94|96,97|103,103|108,109|117,118|132,132|146,148|151,155|161,162|170,170|172,172|174,175|177,178|191,191|193,194|222,228|231,231|234,242 HHH-HHHHH--HH-HHHHT-----SH-HHH???EEE-E-----TTE---EEE?SGGG------??---?--S-S-S??STT-?H--HHHG-GGSS-BS-???-S----TT?-----?TT------?------G-------------GGB-?SHHHH---??SS-??---?B?T-TT-TT?-----------B?TT--------------------?-----?HHHHHHT??S??HHHHHHHHS 2J7A|C PF13437.1_HlyD_3_seed 147 246 !Q:3,3|6,6|10,10|12,13|15,27|29,31|33,34|36,38|40,43|46,50|53,54|56,59|62,71|73,75|77,81|83,83|85,85|90,90|92,93|100,111|114,114|119,119|121,121|123,126|128,130|133,139|141,143|150,176|178,181|184,192|195,199|201,205|208,209|213,213|215,238|240,243|246,246 Q:0,2|4,5|7,9|11,11|14,14|28,28|32,32|35,35|39,39|44,45|51,52|55,55|60,61|72,72|76,76|82,82|84,84|86,89|91,91|94,99|112,113|115,118|120,120|122,122|127,127|131,132|140,140|144,149|177,177|182,183|193,194|200,200|206,207|210,212|214,214|239,239|244,245 EEE?SS?EEE-E--E--?--?---?--?B---T-?E---E?-?-SS?---?SE--E----EE?----?----S---E-----E-E-EEEE-E-?GGGSTT??----------TT?EEEE-B?S----S-?-SS---?---E---EEEEEE?--?--?------??----?-------T----TS?-----?--EE-----E-----EE--EEE?S------------------------S????TT- 2F1M|A PF13439.1_Glyco_transf_4_seed 52 234 !Q:3,4|6,6|10,12|28,28|31,31|37,39|42,43|47,49|51,55|60,78|93,96|100,101|105,107|121,127|135,164|180,183|187,187|207,217|219,220|223,226|228,228 Q:0,2|5,5|7,9|13,27|29,30|32,36|40,41|44,46|50,50|56,59|79,92|97,99|102,104|108,120|128,134|165,179|184,186|188,206|218,218|221,222|227,227|229,233 EEE??S?TTS-??HHHHHHHHHHHHHHH-TT?EEEEE---ES??TTS???T-----TEEE???????????????????HHHHHHHHHHHHHH--??SEE--EEE???SSSHHHHHHHHEE-------SSEEEEE????-------------------------?HHHHHHHHHSTTHHH----HHT?SEEEESSHHHHHHHHHHHS-----------S??EE????B?HHHHH 2GEJ|A PF13442.1_Cytochrome_CBB3_seed 488 179 !Q:0,3|5,5|11,11|13,13|15,18|22,22|24,24|27,27|29,34|37,42|45,49|51,65|67,73|75,75|77,77|82,89|94,100|102,102|109,115|119,120|122,122|124,136|138,142|144,146|148,152|156,156|158,159|161,163|165,167 Q:4,4|6,10|12,12|14,14|19,21|23,23|25,26|28,28|35,36|43,44|50,50|66,66|74,74|76,76|78,81|90,93|101,101|103,108|116,118|121,121|123,123|137,137|143,143|147,147|153,155|157,157|160,160|164,164|168,178 ???-S?HHHHH-H-H----STT-S-ST-T------TT------GG-----G------------???T-------T?S-TTTH--------HHHT-------T?STTHHH-------HHH--H-T-------?-----T-----T---S?----GGG-G-?S---S-??HHHHHHHHHHH 1H9X|A PF13443.1_HTH_26_seed 196 122 !Q:1,1|6,7|12,15|17,22|27,31|33,37|39,44|47,52|54,60|62,63|72,73|75,86|88,89|101,104|108,108|110,114|118,119|121,121 Q:0,0|2,5|8,11|16,16|23,26|32,32|38,38|45,46|53,53|61,61|64,71|74,74|87,87|90,100|105,107|109,109|115,117|120,120 H-HHHH--HHHT----T?----?HHHH-----H-----H------HH------T-----??H--HHHHHHHT--T-?-------???H--HHHHHHHHHHT?-?-GGG-T?----EEE--E? 2XIU|A PF13444.1_Acetyltransf_5_seed 244 151 !Q:3,3|10,31|34,37|40,40|47,50|52,52|55,70|77,77|84,97|103,112|116,116|119,124|136,148 Q:0,2|4,9|32,33|38,39|41,46|51,51|53,54|71,76|78,83|98,102|113,115|117,118|125,135|149,150 HHH-HHHTTT???????---????-??---??TT??--TT?EEEEEE?---T-TS?---------------EEEEEE-EEETTS--?----------?HHHHH?---------GGG?SS?????-TTEEEEEEEEE???-?????????TT 3P2F|A PF13445.1_zf-RING_UBOX_seed 80 83 !Q:0,0|4,5|7,10|15,21|24,24|26,29|31,31|34,34|47,65|67,67|70,78|80,81 Q:1,3|6,6|11,14|22,23|25,25|30,30|32,33|35,46|66,66|68,69|79,79|82,82 ?TTT??B?--?TTSS?------EE-E---?S-SS?EEEHHHHHHHHH-------------------H?SS---?-----B??T 2YU4|A PF13447.1_Multi-haem_cyto_seed 11 314 !Q:0,3|10,15|18,19|21,21|28,39|47,47|61,76|79,79|81,89|91,91|94,94|104,104|107,107|109,109|115,115|117,117|129,129|131,131|134,134|136,136|140,140|144,145|160,160|164,165|185,185|188,188|192,192|198,198|202,204|206,207|218,218|221,221|223,226|229,229|232,232|234,234|245,246|267,267|304,304|312,313 Q:4,9|16,17|20,20|22,27|40,46|48,60|77,78|80,80|90,90|92,93|95,103|105,106|108,108|110,114|116,116|118,128|130,130|132,133|135,135|137,139|141,143|146,159|161,163|166,184|186,187|189,191|193,197|199,201|205,205|208,217|219,220|222,222|227,228|230,231|233,233|235,244|247,266|268,303|305,311 ????HHHHHT-----?TT??S?EETTTT-------?????HHHHTTT?HHHHHHHHTHHHH??----?---------TT?S---------S?TT?SSSTTHHHH-HH-T?HHHHH?S?HHHHHHHHHTS?T-TT?S?SSS?TTT??HHHHTSGGGGTTTS?STT??HHHHHHHSHHHHHHHHHGG-GS?TTS?GGGTT-TTT???S??HHHHHSEETT-EE?S?-??TT?SS?S?TTSTTTTTTT--TSHHHHHHHHHHHHHHTTTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?STTTTTS?? 1FGJ|A PF13450.1_NAD_binding_8_seed 465 161 !Q:2,7|11,12|18,18|21,22|24,25|27,31|33,37|39,43|45,54|56,57|61,64|66,66|68,68|71,71|74,75|79,81|84,86|89,95|97,98|100,106|111,111|113,113|116,120|122,122|125,125|127,134|136,137|139,145|148,148|150,151|154,156|159,159 Q:0,1|8,10|13,17|19,20|23,23|26,26|32,32|38,38|44,44|55,55|58,60|65,65|67,67|69,70|72,73|76,78|82,83|87,88|96,96|99,99|107,110|112,112|114,115|121,121|123,124|126,126|135,135|138,138|146,147|149,149|152,153|157,158|160,160 EE??----SHH--HHHHH-HH--H--G-----G-----G-----T--?----?--E--EEE?---S-S-SS-SS--GGG-?-EE---EE-------T--T-------EEEE-T-TS-??-?E-EE-S-----?--H--H-------HH-H--HH---HT-T 1O94|A PF13452.1_MaoC_dehydrat_N_seed 39 195 !Q:0,1|7,8|11,11|13,16|18,19|31,44|47,47|54,64|66,66|70,70|73,73|77,81|83,87|90,96|102,102|107,116|118,121|129,129|135,135|138,144|146,146|149,149|162,169|172,172|174,174|185,185|195,195 Q:2,6|9,10|12,12|17,17|20,30|45,46|48,53|65,65|67,69|71,72|74,76|82,82|88,89|97,101|103,106|117,117|122,128|130,134|136,137|145,145|147,148|150,161|170,171|173,173|175,184|186,194 ??TTSEE--EE-E?--?B??HHHHHHHHHHH--??------??--TT-TSSSSS--------???B?GGG-HH-HHT-----H-----HH-------HHGGG?SGGG---?--??--S----TTEEEEE-EEEEB?TT??---?-B?TT?BEEEEEEEEEEE?-?-----SS-E-EEEEEEEEEE-ETTEEEEEE- 1IQ6|A PF13454.1_NAD_binding_9_seed 180 274 !Q:0,1|3,4|20,24|28,37|42,42|45,46|49,52|56,58|61,62|64,68|70,72|74,82|85,86|92,92|97,101|104,104|114,118|122,141|147,147|149,149|151,152|154,155|171,171|174,174|177,191|194,194|196,198|200,200|204,206|208,208|212,212|217,222|225,228|234,234|236,238|241,242|246,246|249,253|255,257|266,266|269,272 Q:2,2|5,19|25,27|38,41|43,44|47,48|53,55|59,60|63,63|69,69|73,73|83,84|87,91|93,96|102,103|105,113|119,121|142,146|148,148|150,150|153,153|156,170|172,173|175,176|192,193|195,195|199,199|201,203|207,207|209,211|213,216|223,224|229,233|235,235|239,240|243,245|247,248|254,254|258,265|267,268|273,273 --E??SHHHHHHHHHHHHHH-----HHH--??----??EEEE-ES-?SS??--SSG---GG??S-----S--?B?--------SS-?TTSSS-STTT----?TT?TTSHHHHHH-----HTT------------?-------HHHHH-H-H??S??BHHHHHHHHHHHHTT?TT-TE---------------EE-S---E-EEE---E-EEE-EEET------TE----EEEEE-E---EE--EET-TS--?--E---EEEEESEE-EE????E 2GMH|A PF13456.1_RVT_3_seed 89 107 !Q:0,0|4,12|19,20|32,32|34,34|42,42|53,60|77,77|86,87|100,101 Q:1,3|13,18|21,31|33,33|35,41|43,52|61,76|78,85|88,99|102,106 ?HHH---------HHHHHH--HHHHHHHHHTT?S-EEEEEES?HHHHHHHTTS---?????HHHHHHHHHHHHHHHT-SSEEEEEE??TTTTHHHHHHHH--HHHHT 3HST|B PF13457.1_SH3_8_seed 69 122 !Q:0,6|13,16|19,19|24,24|32,34|38,40|44,47|49,49|52,55|59,62|65,65|68,79|81,86|91,101|104,107 Q:7,12|17,18|20,23|25,31|35,37|41,43|48,48|50,51|56,58|63,64|66,67|80,80|87,90|102,103|108,121 ??-????EEEEES--??TT?EEBS-SSSSSTT???EEE---GGG----G?SS?---EEE?-??EE?SS--------?---E------EEEE-----------EE----TTEEEEEEETTTEE 1M9S|A PF13458.1_Peripla_BP_6_seed 259 971 !Q:8,8|10,10|12,14|18,20|22,23|27,28|44,47|49,49|51,65|69,72|74,75|77,81|83,84|89,89|92,92|94,95|98,99|101,101|114,115|117,119|121,123|127,127|130,130|132,132|134,134|142,142|145,146|149,149|152,154|157,167|171,174|176,176|178,183|185,194|196,200|203,210|212,215|217,220|222,230|232,232|234,236|239,240|242,243|245,256|258,258|260,260|263,264|267,272|278,289|291,296|298,303|305,312|314,321|323,338|340,340|343,343|346,346|348,349|352,353|358,358|362,362|364,364|366,368|371,372|376,376|379,382|385,385|387,387|389,390|393,405|408,411|415,418|420,421|423,427|429,436|439,442|447,447|451,452|454,459|461,478|480,483|488,490|497,497|503,504|506,506|508,511|513,513|515,519|522,529|532,533|537,540|542,542|545,549|553,554|556,557|561,568|570,573|576,578|580,580|582,588|590,600|604,604|607,615|617,618|620,625|627,631|633,639|642,651|660,661|664,671|673,676|678,690|692,696|698,716|718,718|722,724|726,728|734,737|741,744|746,746|750,762|765,768|770,778|780,787|789,800|804,813|815,818|820,835|838,838|840,840|842,842|844,845|847,850|852,856|858,867|869,875|877,877|879,891|893,895|898,906|908,912|914,918|920,920|923,924|926,929|931,944|947,949|953,953|955,956|958,959|962,965|967,969 Q:0,7|9,9|11,11|15,17|21,21|24,26|29,43|48,48|50,50|66,68|73,73|76,76|82,82|85,88|90,91|93,93|96,97|100,100|102,113|116,116|120,120|124,126|128,129|131,131|133,133|135,141|143,144|147,148|150,151|155,156|168,170|175,175|177,177|184,184|195,195|201,202|211,211|216,216|221,221|231,231|233,233|237,238|241,241|244,244|257,257|259,259|261,262|265,266|273,277|290,290|297,297|304,304|313,313|322,322|339,339|341,342|344,345|347,347|350,351|354,357|359,361|363,363|365,365|369,370|373,375|377,378|383,384|386,386|388,388|391,392|406,407|412,414|419,419|422,422|428,428|437,438|443,446|448,450|453,453|460,460|479,479|484,487|491,496|498,502|505,505|507,507|512,512|514,514|520,521|530,531|534,536|541,541|543,544|550,552|555,555|558,560|569,569|574,575|579,579|581,581|589,589|601,603|605,606|616,616|619,619|626,626|632,632|640,641|652,659|662,663|672,672|677,677|691,691|697,697|717,717|719,721|725,725|729,733|738,740|745,745|747,749|763,764|769,769|779,779|788,788|801,803|814,814|819,819|836,837|839,839|841,841|843,843|846,846|851,851|857,857|868,868|876,876|878,878|892,892|896,897|907,907|913,913|919,919|921,922|925,925|930,930|945,946|950,952|954,954|957,957|960,961|966,966|970,970 SEEEEEEE?S-S---STT---T--TTS--HHHHHHHHHHHHHHH----T-S---------------EET----T--E-----E--EEEE-EE-E-?TT-?H-HHHHHHHHHHHH--H---S?--EEE-EE-E?S?HHHHHHH-HH--HH-HH---HT-?---------EEE----E?S---???G----------G-----GG--------T----T----T-?------?T-T---EE--E?-S----?------?H-H-HH--HH------HHHHH------------H------H------H--------T--------T--------??------E-EE-EE-E--ES--SHHH-HHH-H-H---HH--HHH-HH----HT-T?E--EE-------------EE----EEE?---T--T?----S?----?--HH----HHHH-HHH--T----??S------------------E----EEEE?-?HHHHHH-HHHHH--H-H----T-T-----GG--------GT-?EEE----E-SS--??-HHH--H--HHH-------?H----HH---H-T-------T-----?-----EEE-ES----??---T--T------S-----S-------HH----------HHHHHHHH--HH--------H----H-------------S-----S-------------?-?-?-H-HHH---H---HHHHH----HHH----H-HHH-------------HH----H---------T--------S---?--?-----HHH----------H----H----------------HH-H-T-T--S?---E-----E----------S-------S-S-----------?-E---EE---------E---?-T-----T-SB--E----E--------?-?---EE---EEE-E??G--GG??--S---T 3Q41|A PF13459.1_Fer4_15_seed 122 107 !Q:3,4|6,7|10,14|16,18|23,28|30,30|36,37|39,39|41,41|43,44|49,64|66,78|80,83|92,92|95,95|99,99|102,103 Q:0,2|5,5|8,9|15,15|19,22|29,29|31,35|38,38|40,40|42,42|45,48|65,65|79,79|84,91|93,94|96,98|100,101|104,106 EEE?-T--TT?????H---HHHH?-----T-TTEEE?-T-T-S-?EEES---------------?S------------?B?--?HHHHHHHH-HH-HHH?TT??EEE 1ROF|A PF13460.1_NAD_binding_10_seed 74 362 !Q:22,26|33,35|37,57|64,65|67,68|70,70|72,74|83,85|87,89|95,103|106,108|110,111|114,121|123,129|133,134|136,137|140,143|151,151|153,155|157,157|159,163|165,165|168,170|172,173|175,177|180,182|184,184|186,190|195,199|203,204|210,217|224,224|226,229|233,234|236,236|239,243|245,249|253,256|258,259|261,264|267,267|274,275|277,277|282,300|303,307|311,318|320,328|330,330|332,336|338,344 Q:0,21|27,32|36,36|58,63|66,66|69,69|71,71|75,82|86,86|90,94|104,105|109,109|112,113|122,122|130,132|135,135|138,139|144,150|152,152|156,156|158,158|164,164|166,167|171,171|174,174|178,179|183,183|185,185|191,194|200,202|205,209|218,223|225,225|230,232|235,235|237,238|244,244|250,252|257,257|260,260|265,266|268,273|276,276|278,281|301,302|308,310|319,319|329,329|331,331|337,337|345,361 EEEESTTSHHHHHHHHHHHHTT----?EEEEEE---S?-??----???---------?SSEEEE??T--T?H---HHHHHHHT---T--?SEEEE??------?TT---T??GG--------G-------HHH--H--HH----HHHHHHH-H---H-T--??-E-EE---E--E-??GG---G?E-----EETT-----EEG--GGSTT?------?GGGHHH-H----HHH--H-HH-----H-----HHH----T--T??--SS-EEEEEE??S-EEES-------?---??--????EE-----ESS--------B????-----T-T-----S?-----?EEEHHHHHHHHHHHHHH 3IUS|A PF13461.1_C-term_anchor_seed 178 96 !Q:4,4|9,9|12,14|19,20|22,22|25,29|32,35|37,51|54,58|60,61|66,72|77,77|80,82|86,86|93,94|96,96 Q:0,3|5,8|10,11|15,18|21,21|23,24|30,31|36,36|52,53|59,59|62,65|73,76|78,79|83,85|87,92|95,95 EEET-TSSE-EE---EEEE--E?SS-----EE----E?-----???----??TT-----E--EEEE?-----?TTSE-EE??-SSS-EEEEEE--E- 2KVZ|A PF13462.1_Thioredoxin_4_seed 52 270 !Q:0,0|2,2|4,5|7,8|12,12|15,15|18,18|27,27|30,30|36,36|40,40|42,42|44,44|46,47|49,49|54,54|60,61|70,79|81,82|91,93|97,97|99,100|102,103|105,105|107,107|113,113|123,126|133,133|138,146|149,156|159,166|169,180|183,203|205,205|207,210|213,213|215,215|220,220|222,222|224,224|228,228|230,232|235,235|240,241|246,247|249,255|258,259|269,269 Q:1,1|3,3|6,6|9,11|13,14|16,17|19,26|28,29|31,35|37,39|41,41|43,43|45,45|48,48|50,53|55,59|62,69|80,80|83,90|94,96|98,98|101,101|104,104|106,106|108,112|114,122|127,132|134,137|147,148|157,158|167,168|181,182|204,204|206,206|211,212|214,214|216,219|221,221|223,223|225,227|229,229|233,234|236,239|242,245|248,248|256,257|260,268 ?S-S--S--SEE-ES?TT?SEEEEEEE?TT?HHHHH-HHH-H-H-H--H-HHHH-HHHTT--SEEEEEEE?-----?-??S--TTTHHHHH---HHT-T??T--T?H-HHHHH-HHHHHHHTH----HHHTTS?HHHH---------HH--------HH--------HH------------TS??-----?-??--------??H-H----HH-H-HHHH-H-H-HHH-T??-SS?EEEE--TTEE--E------?TT??HHHHHHHHT? 3L9V|A PF13463.1_HTH_27_seed 61 92 !Q:0,1|8,8|14,22|25,25|27,27|29,29|38,40|46,51|61,62|66,67|72,72|75,75|78,82|88,88 Q:2,7|9,13|23,24|26,26|28,28|30,37|41,45|52,60|63,65|68,71|73,74|76,77|83,87|89,91 ??HHHHHH-HHHHT---------TS?B?H-HHHHHHTT??-HHHHH------HHHHHHHHT--TSE--EEEE?SS?TT?----EEEEE?HHH 3K0L|A PF13465.1_zf-H2C2_2_seed 163 64 !Q:5,7|9,11|13,13|15,15|18,38|40,46|48,48|50,51|53,54|56,59 Q:0,4|8,8|12,12|14,14|16,17|39,39|47,47|49,49|52,52|55,55|60,63 HHHHH---T---H-H-HH-------??-?-----?----E-------E?T--T--T?--?EESS 2EOH|A PF13466.1_STAS_2_seed 89 107 !Q:9,9|14,14|16,16|24,25|28,35|38,39|41,45|48,48|59,59|76,76|79,81|85,85|88,90|92,92|94,94|97,97 Q:0,8|10,13|15,15|17,23|26,27|36,37|40,40|46,47|49,58|60,75|77,78|82,84|86,87|91,91|93,93|95,96|98,106 EEEEEEESH-HHHH-H-HHHHHHH--HH--------HS--S--???EE-EEEEEEEEEE?HHHHHHHHHHHHHHHH-TT-??EEE-ES-??H-H-HH-HHHHHHTGG 1T6R|A PF13467.1_RHH_4_seed 57 101 !Q:5,11|41,42|60,82|84,84 Q:0,4|12,40|43,59|83,83|85,100 SEEEE-------EEEETTEEEEEEEEHHHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHS-----------------------S?TTHHHHHHHHHHHHHH 3KK4|A PF13468.1_Glyoxalase_3_seed 115 398 !Q:7,7|9,10|15,18|22,23|25,26|28,29|31,40|47,47|50,59|68,70|72,73|75,79|81,81|87,87|89,91|93,93|95,99|106,122|128,131|133,136|139,140|142,144|149,168|174,178|180,189|197,204|206,209|211,211|213,214|223,232|234,234|236,236|238,238|242,248|252,253|258,276|283,284|288,290|293,306|309,311|314,317|323,327|329,329|334,339|345,351|353,355|357,357|367,369|373,374|378,379|384,384|388,393|397,397 Q:0,6|8,8|11,14|19,21|24,24|27,27|30,30|41,46|48,49|60,67|71,71|74,74|80,80|82,86|88,88|92,92|94,94|100,105|123,127|132,132|137,138|141,141|145,148|169,173|179,179|190,196|205,205|210,210|212,212|215,222|233,233|235,235|237,237|239,241|249,251|254,257|277,282|285,287|291,292|307,308|312,313|318,322|328,328|330,333|340,344|352,352|356,356|358,366|370,372|375,377|380,383|385,387|394,396 EEEEEEE?T--TGGG-???GGG--S--S??E----------EEEEET-TT----------TEEEEEEE?--S--S-----S-EEEEE-E---E-S----?HHHHHH-----------------HTTST----G----GG--T-?-TTTH--------------------HHHTT-----T------?--?EEEEEEE--------E?---S?H--HHHHHHHH----------T-T-T?EEE-------EEE--EEEE??-------?????-----EEEEEE--EEE?--SS?-?-----------SS???EE----EEESS?----T-THHH------HHHTT-------T?-?T-TEEEEEEEE---EET--THH--HHHH-HHH------HHH? 3P8A|A PF13469.1_Sulfotransfer_3_seed 403 635 !Q:1,1|5,6|8,9|11,11|14,14|16,36|42,42|46,132|141,141|149,149|151,219|226,237|249,249|256,259|261,261|264,268|273,274|276,291|300,301|303,311|315,319|323,324|335,336|338,338|348,353|361,361|366,368|370,376|379,379|381,381|387,387|390,400|406,406|409,409|416,423|425,425|428,429|444,462|491,545|551,551|556,595|602,603|608,609|615,615|624,632 Q:0,0|2,4|7,7|10,10|12,13|15,15|37,41|43,45|133,140|142,148|150,150|220,225|238,248|250,255|260,260|262,263|269,272|275,275|292,299|302,302|312,314|320,322|325,334|337,337|339,347|354,360|362,365|369,369|377,378|380,380|382,386|388,389|401,405|407,408|410,415|424,424|426,427|430,443|463,490|546,550|552,555|596,601|604,607|610,614|616,623|633,634 S?EEE--E??T-TS-S---------------------HHHHH-HHH---------------------------------------------------------------------------------------TTSTTEEE?BHHHHHS?S----------------------------------------------------------------?-???GGGGGG?-----------HHHHHHHHHHH-HHHHHS?---S?SS?????TTSB??T----------------HHHHGGGT??S---------TGG-----GTS??HHHHHHHHTS??H-HHHHHHHHH------HHHHTTT?TTSE---E-------EE-E?THHHH?HH-----------HHHHH?TT?EEEEEE--?----?G-GG--THHHHHHHHHHHTT-------------------TSBSSSSHHHHHHHHHHHHHHHHHHHHH-------------------------------------------------------HHTTS?GGGE----------------------------------------EEEEHH--HHHH?-HHHHH-HHHHHHTT?-----???HH 2ZQ5|A PF13472.1_Lipase_GDSL_2_seed 323 742 !Q:6,7|10,12|14,20|22,24|26,35|37,37|39,59|61,62|64,71|73,80|83,85|87,88|91,92|94,96|99,122|124,131|138,150|152,152|154,154|156,156|158,158|162,164|167,175|178,182|184,210|212,222|224,224|226,232|234,234|238,281|284,297|301,304|306,307|310,310|313,313|315,319|321,321|325,325|327,393|395,397|399,405|409,411|416,416|420,422|424,426|430,430|432,444|446,446|448,454|456,463|465,465|467,467|469,470|472,485|488,489|491,491|495,543|549,552|555,555|557,561|563,565|567,567|569,575|577,586|588,589|591,593|595,597|599,600|602,602|604,609|611,615|618,622|627,631|634,638|640,647|649,657|659,665|669,676|678,680|682,682|684,719|723,726|728,730|733,733|735,735 Q:0,5|8,9|13,13|21,21|25,25|36,36|38,38|60,60|63,63|72,72|81,82|86,86|89,90|93,93|97,98|123,123|132,137|151,151|153,153|155,155|157,157|159,161|165,166|176,177|183,183|211,211|223,223|225,225|233,233|235,237|282,283|298,300|305,305|308,309|311,312|314,314|320,320|322,324|326,326|394,394|398,398|406,408|412,415|417,419|423,423|427,429|431,431|445,445|447,447|455,455|464,464|466,466|468,468|471,471|486,487|490,490|492,494|544,548|553,554|556,556|562,562|566,566|568,568|576,576|587,587|590,590|594,594|598,598|601,601|603,603|610,610|616,617|623,626|632,633|639,639|648,648|658,658|666,668|677,677|681,681|683,683|720,722|727,727|731,732|734,734|736,741 EEEESH--HH---H?------B---T----------T-B---------------------S--S-------?S--------HH---H--HH--H---HH------------------------H--------HHHTTB?--------?---E-E-E-E-EEE?--TT---?-?---HH-----H---------------------------H-----------H-H-------H-HHH--------------------------------------------HT--------------GGG??--S--EE-EE-E--??-T-TTT?T-------------------------------------------------------------------T---S???----HHH---HHHH-HHH---H---HHH-H-----------?-G-G-------G--------E-E-E--E----?-?---????TT--T?TTS?------------------------------------------------HHHHH----HH-H-----H---H-H-------H----------H--H---H---H--H-T------T--??-EE---?-HHHH-----HH-----H--------S---------T-------TGG--------G---G-B?-----------------------------------TTS----S---SB?H-HHHHHH 2WAB|A PF13473.1_Cupredoxin_1_seed 62 166 !Q:0,12|16,21|24,33|35,36|42,46|53,54|56,64|69,69|74,74|78,78|81,81|84,84|88,101|112,116|119,119|122,122|125,126|136,138|140,140|149,151|154,156|158,159 Q:13,15|22,23|34,34|37,41|47,52|55,55|65,68|70,73|75,77|79,80|82,83|85,87|102,111|117,118|120,121|123,124|127,135|139,139|141,148|152,153|157,157|160,165 ---------??-?SEE-----?EE----------E--TTEEE-----EEEEES--S---------SEES?EEEE?TTS?EE-EE-EEE????----------GGGSEEEETT-----TT-EE-EE??TTSEEEEEE???S?EEEEEEET---TS?--S--EEEEEE 2J55|A PF13474.1_SnoaL_3_seed 92 191 !Q:8,8|12,12|17,17|26,27|29,31|34,34|38,40|43,45|47,48|51,54|68,71|73,73|75,79|81,82|89,90|92,93|95,95|99,102|104,106|108,108|110,110|112,115|123,124|132,150|158,158|162,163|165,165|167,168|171,174|183,183|185,190 Q:0,7|9,11|13,16|18,25|28,28|32,33|35,37|41,42|46,46|49,50|55,67|72,72|74,74|80,80|83,88|91,91|94,94|96,98|103,103|107,107|109,109|111,111|116,122|125,131|151,157|159,161|164,164|166,166|169,170|175,182|184,184 HHHHHHHH-HHH-HHTT?HHHHHHHB??H---HH?EEE?--TT?-?E--EE----HHHHHHHHHHHHH----H-T-?---S--EEEEEE--E--E-EEE----E---E-E-T----TEEEEEE--EEEEEEE??-??-???????----??EEEEEEE-EEE--E-E??TT--??EEEEEEEE-E?--??? 3B7C|A PF13476.1_AAA_23_seed 469 1093 !Q:6,7|9,9|13,27|29,29|31,35|37,39|41,44|46,49|51,68|70,75|77,89|91,92|94,101|106,114|116,124|133,133|137,140|142,143|145,145|147,147|149,153|155,212|214,216|218,239|241,251|254,297|300,301|303,305|309,313|318,346|350,352|356,451|458,462|466,467|470,471|473,475|477,480|483,483|487,501|503,514|517,528|530,531|534,537|539,541|544,558|561,561|563,563|565,569|571,572|574,576|580,593|595,595|597,599|601,604|607,659|662,664|666,670|672,676|678,678|680,682|684,685|687,687|690,690|692,732|739,760|762,765|768,768|779,837|840,840|842,842|844,845|847,853|855,855|858,860|862,868|871,872|874,875|877,877|879,880|884,893|895,901|905,973|979,997|999,1005|1008,1009|1011,1058|1061,1063|1066,1069|1075,1077|1080,1081|1083,1086|1088,1089 Q:0,5|8,8|10,12|28,28|30,30|36,36|40,40|45,45|50,50|69,69|76,76|90,90|93,93|102,105|115,115|125,132|134,136|141,141|144,144|146,146|148,148|154,154|213,213|217,217|240,240|252,253|298,299|302,302|306,308|314,317|347,349|353,355|452,457|463,465|468,469|472,472|476,476|481,482|484,486|502,502|515,516|529,529|532,533|538,538|542,543|559,560|562,562|564,564|570,570|573,573|577,579|594,594|596,596|600,600|605,606|660,661|665,665|671,671|677,677|679,679|683,683|686,686|688,689|691,691|733,738|761,761|766,767|769,778|838,839|841,841|843,843|846,846|854,854|856,857|861,861|869,870|873,873|876,876|878,878|881,883|894,894|902,904|974,978|998,998|1006,1007|1010,1010|1059,1060|1064,1065|1070,1074|1078,1079|1082,1082|1087,1087|1090,1092 EEEEEE--E-TTE---------------E-E-----E---E----E----E?----------------?S------E-------------E--E--------EEEE-?-------T---------TSSHHHHH-HHH----H--H-H-H-----H-?-----??------------???---------------------------------?T---T----------------------T-----------TB-?------------------------------------------TT?-S---EEE-----EEEE-----------------------------EEE---TTE------------------------------------------------------------------------------------------------EEEEEE-----EEE--TT--E---E----EE-EEE---------------E------------TT------------E--EE----E?--SH---------------HH-H-H-----H--H---HHH--------------H-H?--S?---HH-----------------------------------------------------HH---H-----H-----H-H---E--E?TT-H-----------------------------------------HHHHHH----------------------S?---HH-HHHHHHHHHH-----------------------------------------------------------TH-H-H--H-------H-HH---H-------HH--H--H-H--HHH----------H-------HHH---------------------------------------------------------------------HHHHH-------------------H-------HH--T?---????---------------------------------------?HH---HH----HHHHH---HH--H----H--HHH 4I99|A PF13477.1_Glyco_trans_4_2_seed 45 249 !Q:2,7|9,11|13,15|17,19|21,23|25,27|29,30|33,35|37,40|44,46|51,54|56,56|62,62|64,66|68,81|85,85|89,107|109,113|116,117|119,120|122,122|124,127|132,133|142,143|149,149|152,153|157,157|166,168|174,174|176,177|181,182|185,186|188,188|190,192|195,197|201,202|205,205|208,216|218,219|222,227|231,231|233,233|237,238|245,245|248,248 Q:0,1|8,8|12,12|16,16|20,20|24,24|28,28|31,32|36,36|41,43|47,50|55,55|57,61|63,63|67,67|82,84|86,88|108,108|114,115|118,118|121,121|123,123|128,131|134,141|144,148|150,151|154,156|158,165|169,173|175,175|178,180|183,184|187,187|189,189|193,194|198,200|203,204|206,207|217,217|220,221|228,230|232,232|234,236|239,244|246,247 EE??????H---H---H---H---H---H--HH---H----HHH---HHHT----T?EEEEE?S---S???---?????--?TTE-EEE??--???????------??S---??HH--H--H-H----HHHH--HHHHHHHT-?SEEEE?SS--TTH-HHHHHHHH---HHTTT?S--EEE--EE??H-H---HH---HTT--TT?TT---------T--HH------HHH-H-HHH--HSSEEE-ES? 2GEJ|A PF13478.1_XdhC_C_seed 296 300 !Q:4,5|20,20|22,23|31,31|34,47|50,50|52,56|58,62|64,76|78,88|91,95|98,104|108,115|117,120|122,145|147,148|150,151|155,158|164,169|171,177|179,179|181,184|186,187|189,189|192,199|201,201|203,203|207,207|215,215|217,217|219,226|228,230|232,232|237,239|252,252|255,256|258,265|272,273|275,275|277,277|279,286 Q:0,3|6,19|21,21|24,30|32,33|48,49|51,51|57,57|63,63|77,77|89,90|96,97|105,107|116,116|121,121|146,146|149,149|152,154|159,163|170,170|178,178|180,180|185,185|188,188|190,191|200,200|202,202|204,206|208,214|216,216|218,218|227,227|231,231|233,236|240,251|253,254|257,257|266,271|274,274|276,276|278,278|287,299 EEEE??STHHHHHHHHHHHT-T-?EEEEEES?TT--------------TS?T-----T-----T-----?-------S-----------SS-----SE-------EEE--------S?---H------------------------H--H--HHH----HHHHH------T?--??--T-T?---E--E-EE--?--???H-H-HHH-HHHHHHT-T-S--------S?-?S-EEEE???HHHHHHHHHHHH-HT--T??------HHHHTT-?B?S?S-??-????SHHHHHHHHHHHH 3ON5|A PF13480.1_Acetyltransf_6_seed 211 360 !Q:4,6|8,11|15,20|24,24|26,29|31,36|38,41|43,43|46,48|51,56|58,65|68,71|73,73|75,81|84,84|86,92|94,97|102,112|114,117|119,123|128,138|141,154|156,156|158,160|168,170|173,181|184,185|187,189|191,191|193,196|202,205|207,210|212,215|217,218|220,223|225,227|232,233|241,241|246,247|249,250|255,255|258,259|261,265|267,268|270,272|277,280|291,294|296,299|301,303|305,305|307,309|313,316|319,322|324,324|328,334|336,348|353,356 Q:0,3|7,7|12,14|21,23|25,25|30,30|37,37|42,42|44,45|49,50|57,57|66,67|72,72|74,74|82,83|85,85|93,93|98,101|113,113|118,118|124,127|139,140|155,155|157,157|161,167|171,172|182,183|186,186|190,190|192,192|197,201|206,206|211,211|216,216|219,219|224,224|228,231|234,240|242,245|248,248|251,254|256,257|260,260|266,266|269,269|273,276|281,290|295,295|300,300|304,304|306,306|310,312|317,318|323,323|325,327|335,335|349,352|357,359 HHHH---H----HHH------HHH-H----T------T----E-EE---EE------E---?----SH----H-H-------HH-H-------H----HHHH-----------H----H-----HHHH-----------TT---??---?---??H-H---HHHHHHH---HS?--------TT--T---E-E----EEEEE----E----T----T--E----E---EEEE--EEEEETT-EEEE--E--EEEE?SS??T-----T--H---HHHH----HHHHHHHHHH----T----T--?S-E---EEE----EE---?S?SST-------T----?--------HHHH----HHH 1NE9|A PF13481.1_AAA_25_seed 101 383 !Q:0,10|12,23|25,25|28,31|35,46|51,54|56,60|64,67|70,72|79,79|83,83|97,122|124,126|129,129|131,147|156,159|162,162|166,168|174,174|177,186|189,189|191,212|214,214|216,218|222,222|227,237|242,253|255,259|261,262|264,266|268,271|273,274|279,279|287,288|290,291|294,298|305,305|307,308|311,313|315,318|320,325|327,328|330,331|333,333|336,339|341,344|355,355|358,358|361,365|367,367|374,382 Q:11,11|24,24|26,27|32,34|47,50|55,55|61,63|68,69|73,78|80,82|84,96|123,123|127,128|130,130|148,155|160,161|163,165|169,173|175,176|187,188|190,190|213,213|215,215|219,221|223,226|238,241|254,254|260,260|263,263|267,267|272,272|275,278|280,286|289,289|292,293|299,304|306,306|309,310|314,314|319,319|326,326|329,329|332,332|334,335|340,340|345,354|356,357|359,360|366,366|368,373 ???--??---?H------------H-HH----HSS-??-??----??EEET----T-----EET----TS---EEEEEE?STT?HHHHHHHHHHHHH--------------------------T???TT?S----?????------??EEEEESSS?---HH-HHH---HHHHH-HH----------TT-S---------------------?H-H---HHH-HHHH-----------HEEE?---------??T-----T--S???T----T--SHHH-HHHHHHH--H--TT----?SEEEEE?G--GG---G?--?S-----?T--T?-H-HH----H----HHHHHHHHHH-HH-HH-?--?E-EEEEEE????---?? 1U9I|A PF13482.1_RNase_H_2_seed 108 338 !Q:6,12|15,18|21,21|23,23|25,33|39,46|48,49|51,51|53,53|55,59|63,64|67,72|74,74|79,79|81,84|101,105|108,112|123,123|129,130|134,143|146,146|149,159|164,166|171,171|183,187|190,190|192,195|197,199|203,206|209,210|212,213|215,229|237,237|240,256|262,264|266,271|273,301|303,314 Q:0,5|13,14|19,20|22,22|24,24|34,38|47,47|50,50|52,52|54,54|60,62|65,66|73,73|75,78|80,80|85,100|106,107|113,122|124,128|131,133|144,145|147,148|160,163|167,170|172,182|188,189|191,191|196,196|200,202|207,208|211,211|214,214|230,236|238,239|257,261|265,265|272,272|302,302|315,337 EEEEEE??---??SS??--SS-S-S?-----?-?EEEEE-------?S--S?E-E-----EEE--SS??-??-T-TEEE?S----SHHHHHHHHHHHHHHH??---SE-----EEESSTTTTH-HHHHH--HTT----------TT-TT-???-----??STTS???EEEE?SSSEEEEBEEE-----EH-H----H---HHT----TS--S??S--------??----?HHHHHHH-HH?-??--?--??--????GGGTS---S------S------?---------------------?S---------?--HHHHHHHHHHHHHHHHHHHHHHH 4FM2|A PF13483.1_Lactamase_B_3_seed 85 362 !Q:13,13|15,15|17,21|23,23|30,91|93,93|98,98|101,108|111,115|118,118|121,151|153,153|157,157|159,180|182,190|193,202|205,205|207,208|210,211|214,214|220,220|225,267|269,271|276,276|279,280|283,284|286,290|297,297|300,301|303,306|311,312|316,319|326,327|329,335|337,337|340,341|354,354 Q:0,12|14,14|16,16|22,22|24,29|92,92|94,97|99,100|109,110|116,117|119,120|152,152|154,156|158,158|181,181|191,192|203,204|206,206|209,209|212,213|215,219|221,224|268,268|272,275|277,278|281,282|285,285|291,296|298,299|302,302|307,310|313,315|320,325|328,328|336,336|338,339|342,353|355,361 EEEEEETTEEEEE-E-T-----T-EEEEES??--------------??------?---???--????------------------------?B?SEEE?SS-????-??GG-----GG?BS-------------------------------S?EEE?S----------------------S---------EE----------EE-E--T--TE-EEEEE-EEEE----------------???---?-??---??----------?-E---EEEE-EE--EE--T-----TEEEEE?TT??S?-??HHHH--HHH?-??SEEEEE??S-------S-SS??HHHHHHHHHHTT?SEEEEES 2I7T|A PF13485.1_Peptidase_MA_2_seed 226 455 !Q:4,7|9,18|22,23|27,41|43,52|54,56|58,79|82,83|85,85|88,95|110,110|112,122|124,133|136,154|157,163|167,168|171,176|187,209|212,237|239,245|248,248|250,254|257,257|259,265|268,268|274,276|280,281|284,287|290,293|296,301|307,307|315,333|336,357|362,363|365,370|372,374|377,379|381,382|388,390|396,400|402,405|407,407|409,416|418,418|420,425|428,428|431,443|445,445|448,452 Q:0,3|8,8|19,21|24,26|42,42|53,53|57,57|80,81|84,84|86,87|96,109|111,111|123,123|134,135|155,156|164,166|169,170|177,186|210,211|238,238|246,247|249,249|255,256|258,258|266,267|269,273|277,279|282,283|288,289|294,295|302,306|308,314|334,335|358,361|364,364|371,371|375,376|380,380|383,387|391,395|401,401|406,406|408,408|417,417|419,419|426,427|429,430|444,444|446,447|453,454 SSSE----E?-----?---TTE--EEE?--------------G----------G---G-----?---?------------SS--S?ST--------HHHHHHHHHTTBTT-T-----------E----------EE-------------------SS-------TTS--TH------HHHHHHHHHH-----------------------HH--------------------------H-------HH-H-----HH?H-------HH-HHHHH---HHH--HH----HH----HH------HHHHS?TTTTSSS?---?------?-------TT--??------------------TTTS??S------H---HH---H--HHHHH---HHHHH-----H----H-H----?---H-H------HH-HH-------------H-HH-----HH 3FUE|A PF13487.1_HD_5_seed 81 107 !Q:2,6|8,8|13,15|17,20|22,22|24,26|39,47|49,50|52,58|60,63|65,67|71,73|81,82|86,86|88,88|90,90|92,94|100,100 Q:0,1|7,7|9,12|16,16|21,21|23,23|27,38|48,48|51,51|59,59|64,64|68,70|74,80|83,85|87,87|89,89|91,91|95,99|101,106 GG---??H-HHHH---H----H-H---HHHHHHHHHHTT--?------T--T-------S?---H---HHH---HHHHHTT??TBS?S-T-T-??BGGGS?HHHHHH 3TMB|A PF13489.1_Methyltransf_23_seed 129 598 !Q:3,3|7,11|14,16|19,25|29,29|32,34|37,43|45,51|53,54|56,56|58,76|78,78|83,83|88,88|91,92|94,127|130,130|133,136|139,153|155,164|166,172|174,178|180,181|184,186|188,189|196,196|198,198|205,232|240,240|242,270|279,303|305,305|307,330|334,358|368,370|373,374|380,380|382,382|386,386|388,395|398,413|422,424|426,426|428,429|431,432|434,434|436,436|439,440|446,449|451,452|454,454|457,493|495,499|504,505|509,526|528,528|530,531|533,537|539,547|549,555|558,573|582,582|586,586|588,593 Q:0,2|4,6|12,13|17,18|26,28|30,31|35,36|44,44|52,52|55,55|57,57|77,77|79,82|84,87|89,90|93,93|128,129|131,132|137,138|154,154|165,165|173,173|179,179|182,183|187,187|190,195|197,197|199,204|233,239|241,241|271,278|304,304|306,306|331,333|359,367|371,372|375,379|381,381|383,385|387,387|396,397|414,421|425,425|427,427|430,430|433,433|435,435|437,438|441,445|450,450|453,453|455,456|494,494|500,503|506,508|527,527|529,529|532,532|538,538|548,548|556,557|574,581|583,585|587,587|594,597 HHH-HHH-----HT---HH-------HHG-GG---SS-------T-------T-?S?E-------------------E-EEEE?STTH-HH--H----------------------------------HH-HH----HH---------------H----------H-------H-----H--ST---T??EEEEEE?S?HHHHHH----------------------------HHHHHHT?S?---------------------------?TTEEEEEE------------------------?S?H------------------------HHH-------------------------HHHHHHSSS???EE--EEEEE-S?GGG?S----?---HH----------------HHHHHHHT---T-E--E--E-E-EE--EEEEE----E-?S-SS-------------------------------------H-----HHHH--HHH------------------H-G--G-----G---------S???----TT?----???-------?HHHHHHHH-HHH-T--??--EEEE 2JG3|A PF13490.1_zf-HC2_seed 461 50 !Q:0,4|6,6|9,10|20,24|26,26|29,29|31,32|34,34|44,44 Q:5,5|7,8|11,19|25,25|27,28|30,30|33,33|35,43|45,49 --?--G-GG--GGHHHHHHT?----S?HH-H--H-HHHHHHHHT?HHHHH 2Q1Z|B PF13492.1_GAF_3_seed 153 412 !Q:0,0|2,2|4,5|12,19|23,23|26,26|30,33|36,40|43,43|47,49|51,51|53,54|57,58|61,61|64,69|73,75|79,81|83,86|89,89|91,92|94,147|150,158|162,164|168,172|179,180|182,186|188,190|193,197|200,201|203,210|212,234|236,247|249,262|270,271|273,297|300,308|311,313|318,321|324,341|348,348|350,350|352,356|358,358|360,368|370,387|389,389|393,393|399,400 Q:1,1|3,3|6,11|20,22|24,25|27,29|34,35|41,42|44,46|50,50|52,52|55,56|59,60|62,63|70,72|76,78|82,82|87,88|90,90|93,93|148,149|159,161|165,167|173,178|181,181|187,187|191,192|198,199|202,202|211,211|235,235|248,248|263,269|272,272|298,299|309,310|314,317|322,323|342,347|349,349|351,351|357,357|359,359|369,369|388,388|390,392|394,398|401,411 ?H-H--HHHHHH--------HHH-HH-HHS-?-?SE-----EE-EEE---E-E--TT--EE-EE------EEE---EST---T??--SS?T--T?-----------------------------------------------------EE-?-------STT-?-HHH-----HHHHHT--S--?--E---EE-----ES??T--------T-------??-------?------T------------T--------------HHHHHTT--T-?----------?------------EE---------EE---EEEE?---SS-----------------?EEEEEE-E-E-----E-S---------S-??-?-------?--?--H-HHH-HHHHH--HHHHHHHHHHT 4EUV|A PF13493.1_DUF4118_seed 102 166 !Q:2,3|5,7|19,20|28,28|32,36|38,41|43,43|45,48|50,52|55,56|58,59|65,65|68,68|72,72|75,77|84,85|91,95|101,103|106,119|122,122|125,125|128,135|146,149|158,158|163,165 Q:0,1|4,4|8,18|21,27|29,31|37,37|42,42|44,44|49,49|53,54|57,57|60,64|66,67|69,71|73,74|78,83|86,90|96,100|104,105|120,121|123,124|126,127|136,145|150,157|159,162 SH--H---HHHHHHHHHHH--HHHHHHS-TTS-----S-?-?S-S----H---HH--H--HHHHH-HH-HHH-SS???SHHHHH--HHHHH-----HHTTS-?-SS?-------------TT?SS?HH--------HHHHHHHHHH----HHHHHHHH-HHHH??? 2KSF|A PF13495.1_Phage_int_SAM_4_seed 83 134 !Q:9,9|12,14|17,18|32,35|41,44|46,50|52,65|67,67|70,71|76,85|94,94|98,105|113,115|129,132 Q:0,8|10,11|15,16|19,31|36,40|45,45|51,51|66,66|68,69|72,75|86,93|95,97|106,112|116,128|133,133 HHHHHHHHH-HH---TT??HHHHHHHHHHHHH----HHTTS----S-----S?----------?--G-GG??HHHH----------HHHHHHHH-TTT?-----??HHHHHHH---HHHHHHHHHHTSS????T 2A3V|A PF13499.1_EF-hand_7_seed 146 145 !Q:1,1|6,6|13,23|29,29|32,33|35,35|38,40|43,43|48,48|57,57|59,59|72,82|85,85|98,98|104,112|120,121|124,124|127,129|132,132|135,135|142,142|145,145 Q:0,0|2,5|7,12|24,28|30,31|34,34|36,37|41,42|44,47|49,56|58,58|60,71|83,84|86,97|99,103|113,119|122,123|125,126|130,131|133,134|136,141|143,144 G?TTTT?HHHHHH-----------HHHHH-HH--H?TT?--SS?EEHH-HHTTTTTT?S?HHHHHHHTTTTT????????-??EE?HHHHHHHHHHHH?TTSHH---------HHHHHHH--HH?TT--?SS-SB?HHHHHH-HH- 1BR1|B PF13500.1_AAA_26_seed 55 425 !Q:27,30|33,36|39,43|46,48|50,50|54,54|56,61|65,66|68,76|82,82|85,85|90,92|94,94|96,96|99,157|161,161|165,165|167,168|172,172|178,178|180,187|195,208|212,212|216,216|218,228|235,235|241,242|244,244|249,250|260,265|267,268|275,278|281,281|283,283|285,291|293,293|297,298|300,303|310,310|312,316|318,322|324,327|329,333|341,347|350,357|363,378|384,384|388,388|391,399|401,407|410,410|414,417|419,419|422,422 Q:0,26|31,32|37,38|44,45|49,49|51,53|55,55|62,64|67,67|77,81|83,84|86,89|93,93|95,95|97,98|158,160|162,164|166,166|169,171|173,177|179,179|188,194|209,211|213,215|217,217|229,234|236,240|243,243|245,248|251,259|266,266|269,274|279,280|282,282|284,284|292,292|294,296|299,299|304,309|311,311|317,317|323,323|328,328|334,340|348,349|358,362|379,383|385,387|389,390|400,400|408,409|411,413|418,418|420,421|423,424 EEEEEEESSTTSSHHHHHHHHHHHHHH----TT??--EE-----EE??-E-EES?E------EEE-?H---------HHHHH-HH-TSSS???H-H-HH----------------------------------------------------------?SEE-ESS?S-?HHH-HHHHH-T---????-HHHHHHH--------------HHH-HTT-T--?--------SEEEEE?SSSTT-?B-SSSS-?BHHHHHHHH------T??EEEEEE?---ST-T-H-------H-HHH--H----HHHHHH-H-----H-----T----T?-?--EEEEEEE?----?-SS?------?TTHHH----------------HHHHH-HHH-SS---------S------?EE-EEE????S?GG-GS 3FPA|A PF13501.1_SoxY_seed 101 131 !Q:7,7|9,10|12,14|17,18|25,29|36,36|41,42|47,49|52,56|64,64|78,78|80,81|83,85|87,88|95,95|98,98|105,105|109,110|117,117|126,130 Q:0,6|8,8|11,11|15,16|19,24|30,35|37,40|43,46|50,51|57,63|65,77|79,79|82,82|86,86|89,94|96,97|99,104|106,108|111,116|118,125 HHHHHHH?S??E---EE-?SSEEEE?---?SEEETT?EEEE--EEEE?-?TT-----EEEEEEE?TTSSSSEEEEEEE?T--T???E--EEEEEE?SS?EEEEEE-EEE--TTEEEE-EEEEEEEE?-??? 2OXH|B PF13504.1_LRR_7_seed 1228 74 !Q:2,7|10,12|14,32|34,38|40,73 Q:0,1|8,9|13,13|33,33|39,39 TT?----?EE---E---?--------------?S-----S-----?-----?----?------?-----?---? 2A0Z|A PF13505.1_OMP_b-brl_seed 190 611 !Q:0,39|41,49|53,53|55,65|67,68|73,73|75,77|79,80|82,153|155,157|159,160|163,164|170,170|172,174|176,178|180,183|185,188|190,195|197,202|205,206|208,208|211,211|214,215|217,229|231,236|240,283|286,302|310,315|318,318|320,320|322,326|328,328|331,335|338,338|340,350|352,353|355,358|362,367|373,417|423,425|427,429|431,431|434,463|465,465|472,473|479,480|483,484|486,491|497,502|504,508|510,514|517,520|522,522|524,528|531,532|535,535|537,538|540,541|543,597|599,601|610,610 Q:40,40|50,52|54,54|66,66|69,72|74,74|78,78|81,81|154,154|158,158|161,162|165,169|171,171|175,175|179,179|184,184|189,189|196,196|203,204|207,207|209,210|212,213|216,216|230,230|237,239|284,285|303,309|316,317|319,319|321,321|327,327|329,330|336,337|339,339|351,351|354,354|359,361|368,372|418,422|426,426|430,430|432,433|464,464|466,471|474,478|481,482|485,485|492,496|503,503|509,509|515,516|521,521|523,523|529,530|533,534|536,536|539,539|542,542|598,598|602,609 ????????-??---??--???----------------???T---------TEE-E-----------E--EEEE-E---E--E??-----???---?-?--------------??????-------??-?-?-----------------------E---E--EE--EEEEE-E---E---E----E----T------T------EE--E-EE-EE--E-------------E------EEE-----?????-----------------------?-??----???EE-----------------EEEEEEE------EE-E-E-----E-ES-----SS-S-----------E--E----EEE------EEEEE---------------------------------------------EEEEE---E---E?SS------------------------------S?EEEEEE--EEEEE--EE--E------EEEEE------E-----T-----TE----E-E-----EE--EE-E--E--E-??-----------------------???????--------??????-------?E---EEEEEEEE? 2M06|A PF13506.1_Glyco_transf_21_seed 54 254 !Q:1,3|5,6|8,9|11,15|19,21|23,27|30,32|34,35|37,39|51,57|63,64|70,70|86,86|88,89|91,91|94,99|103,107|109,112|118,118|120,122|124,126|128,134|136,136|139,142|150,151|154,156|158,162|164,170|187,191|202,202|209,209|211,212|215,220|223,225|227,230|235,241|248,249 Q:0,0|4,4|7,7|10,10|16,18|22,22|28,29|33,33|36,36|40,50|58,62|65,69|71,85|87,87|90,90|92,93|100,102|108,108|113,117|119,119|123,123|127,127|135,135|137,138|143,149|152,153|157,157|163,163|171,186|192,201|203,208|210,210|213,214|221,222|226,226|231,234|242,247|250,253 H---H--H--T----?EEE---E?----SS??-S--H---HHHHHHHHHHH----???SEEEE??TTEEE?TTHHHHHHHHHHHSS-S??E-EE?-???-BSS??---H----HHHHH-T-??T---H-------H-HH----HTHHHHH--HH---T-----T?--????SSSEEEEHHHHHHHTT???--SSSSHHHHHH-HHHHTT-T??EE?????-EE---E????SHHH-------HHHHHH--HHHH 4HG6|A PF13507.1_GATase_5_seed 255 451 !Q:0,1|8,8|12,13|26,26|31,31|33,34|36,44|46,46|48,50|52,60|62,70|72,80|83,91|93,104|108,110|116,117|119,119|126,126|132,133|142,147|159,159|161,161|163,163|166,166|174,174|184,185|189,200|203,229|232,233|237,238|243,243|248,248|251,252|254,257|259,259|261,270|272,272|274,275|278,278|281,284|286,287|289,289|296,297|302,304|308,312|320,321|328,328|335,335|337,343|345,346|348,348|350,351|353,358|365,366|375,375|396,396|398,398|400,412|414,414|416,417|419,423|425,437 Q:2,7|9,11|14,25|27,30|32,32|35,35|45,45|47,47|51,51|61,61|71,71|81,82|92,92|105,107|111,115|118,118|120,125|127,131|134,141|148,158|160,160|162,162|164,165|167,173|175,183|186,188|201,202|230,231|234,236|239,242|244,247|249,250|253,253|258,258|260,260|271,271|273,273|276,277|279,280|285,285|288,288|290,295|298,301|305,307|313,319|322,327|329,334|336,336|344,344|347,347|349,349|352,352|359,364|367,374|376,395|397,397|399,399|413,413|415,415|418,418|424,424|438,450 ??EEEEEE?TTB??HHHHHHHHHHTT?EEEE-E--E---------H-H---H---------H---------H---------HT---------S?---------?-GGG--?SEEEE??B?GGGGTT-STTHH--HHHHHHHS------HHHHHHHHHHH-H-S-SS?EEEEETH-HHHHHHTTG--GGS------------TT---------------?-----------TT??EEE??TTSS?EEEE-EE--E----E-E?-?---?---S?G--GG-TT?---T--T?EEEEEE--EESS--?EEE?----SSHHHHH--HHHHTT?EEEEEB?T-------T--S?B??S------TTTSSS??GGGEEEEE?TTSSEEEESSBGGGSSBGGG?S-S??-----------T-T??S-----B------------?TTHHHHHHHHHHH 1T3T|A PF13508.1_Acetyltransf_7_seed 163 291 !Q:2,4|6,6|11,11|14,24|28,30|33,33|35,37|40,40|49,59|63,65|67,74|76,78|81,88|94,100|103,104|107,107|114,114|117,119|122,124|129,134|136,142|144,146|150,153|156,170|172,176|178,194|196,206|208,219|221,232|234,254|256,278|280,280|288,288 Q:0,1|5,5|7,10|12,13|25,27|31,32|34,34|38,39|41,48|60,62|66,66|75,75|79,80|89,93|101,102|105,106|108,113|115,116|120,121|125,128|135,135|143,143|147,149|154,155|171,171|177,177|195,195|207,207|220,220|233,233|255,255|279,279|281,287|289,290 HH?--E-EEEE-EE-----------TTE---EE-E---EE-EEEEEEEE-----------ETT---E--------E---EE--------EEEEE-------EE--EE?GGGGGG?HH---HH---HHHH------H-------H---HHH----HH---------------H-----T---?---?---------E-----------E------------E------------E-----?-------?-------S------------?----------H-HHHHTTT?EE 1QSN|A PF13509.1_S1_2_seed 96 86 !Q:12,13|19,19|21,27|29,31|35,38|47,52|54,61|73,73|77,79|84,84 Q:0,11|14,18|20,20|28,28|32,34|39,46|53,53|62,72|74,76|80,83|85,85 TTEEEEEEEEEE?-SSEEE-E-------E---ETT----EEEEEEGG------G--??--??TTSEEEEEEEE?TTS--?EEEE?S 3GO5|A PF13510.1_Fer2_4_seed 254 135 !Q:12,12|19,19|30,49|51,51|53,55|57,57|59,64|66,72|74,76|81,81|84,84|89,102|106,108|110,112|114,114|121,121|123,124|132,132 Q:0,11|13,18|20,29|50,50|52,52|56,56|58,58|65,65|73,73|77,80|82,83|85,88|103,105|109,109|113,113|115,120|122,122|125,131|133,134 EEEEEEEETTEE-EEEEET?BHHHHHHHTT----------------?-?-B?S?-?T-T------T???---?B???SSTT?SS?EEEE----?-------??STT???E---E-EEETTS?B??TTEEEEE?SS 3I9V|3 PF13512.1_TPR_18_seed 19 166 !Q:0,0|3,8|24,24|39,39|42,42|61,61|76,76|79,79|99,132|141,143|152,152 Q:1,2|9,23|25,38|40,41|43,60|62,75|77,78|80,98|133,140|144,151|153,165 ?SS??????HHHHHHHHHHHHHTT?HHHHHHHHHHHHHH?TT?TTHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHH?TT?TTHHHHHHHHHHHHHHHHT------------------????????????????HHHHHHHH---HHHHHHHH?TTSTTHHHHHHHH 2XEV|A PF13513.1_HEAT_EZ_seed 261 95 !Q:4,9|15,15|18,20|23,31|40,42|46,47|58,61|65,65|67,71|75,77|80,81|86,87|95,95 Q:0,3|10,14|16,17|21,22|32,39|43,45|48,57|62,64|66,66|72,74|78,79|82,85|88,94 HHHH------HHHHH-HH---HH---------TTTTTHHH---HGG--GHHHHHHHHH----HHT-T?----SSH---HH--HHHH--HHHHHHT- 1EJY|I PF13516.1_LRR_6_seed 889 104 !Q:0,5|8,16|19,23|25,43|45,58|61,63|66,69|71,77|79,82|85,88|90,102 Q:6,7|17,18|24,24|44,44|59,60|64,65|70,70|78,78|83,84|89,89|103,103 ?-----TT--??-----EE-----E-----?----?--------S--?-?-----?---HH---HH----H-------H----HH----H-------------H 2A0Z|A PF13517.1_VCBS_seed 1255 227 !Q:0,0|4,5|8,9|13,14|16,19|21,41|43,47|49,68|72,79|81,86|88,93|95,100|102,103|105,117|119,135|137,137|139,141|145,152|155,156|160,161|163,183|185,188|190,199|201,207|212,214|220,222 Q:1,3|6,7|10,12|15,15|20,20|42,42|48,48|69,71|80,80|87,87|94,94|101,101|104,104|118,118|136,136|138,138|142,144|153,154|157,159|162,162|184,184|189,189|200,200|208,211|215,219|223,226 ?SSS--SS??EEE--E----E----------------?----S-----S?-------------------EEE--------E--?---B-?----S------S--S----?--------B?----------?-?---E-E---EES?-------SB--TTB--S-----------------???-T----T----------T----?-?EEEE--?SSSSS?-?EEEE 3VI4|A PF13518.1_HTH_28_seed 193 101 !Q:5,7|9,9|12,12|15,16|18,20|22,22|25,29|33,37|45,48|50,50|54,54|63,63|65,65|68,68|70,71|73,98 Q:0,4|8,8|10,11|13,14|17,17|21,21|23,24|30,32|38,44|49,49|51,53|55,62|64,64|66,67|69,69|72,72|99,100 SHHHH---H-HH-HH--H---H?TT?---?HHH-----HHHHHTS---?H-HHH-HHHHHHHH-H-HT-S--S--???-?------?--?---?----?SG 1HCR|A PF13519.1_VWA_2_seed 168 917 !Q:7,7|12,22|24,32|35,76|78,83|85,101|106,106|108,108|113,121|125,127|130,139|141,153|155,155|157,162|165,170|172,172|174,175|180,188|190,196|198,211|213,229|231,236|238,241|243,254|256,273|275,282|284,287|289,299|301,309|311,312|316,320|324,328|330,331|334,341|344,344|346,383|385,395|397,412|415,417|419,419|422,458|461,462|465,468|470,470|473,511|513,518|520,547|549,553|555,555|557,557|559,559|564,595|598,613|615,617|620,625|627,641|644,644|646,688|690,691|693,695|697,698|701,702|704,706|709,713|715,716|720,728|731,731|733,743|745,751|753,755|758,758|760,760|765,765|767,806|808,808|812,812|814,814|817,819|821,822|824,840|842,843|847,847|849,850|853,854|857,861|863,868|871,877|882,884|888,889|894,906|909,911|915,915 Q:0,6|8,11|23,23|33,34|77,77|84,84|102,105|107,107|109,112|122,124|128,129|140,140|154,154|156,156|163,164|171,171|173,173|176,179|189,189|197,197|212,212|230,230|237,237|242,242|255,255|274,274|283,283|288,288|300,300|310,310|313,315|321,323|329,329|332,333|342,343|345,345|384,384|396,396|413,414|418,418|420,421|459,460|463,464|469,469|471,472|512,512|519,519|548,548|554,554|556,556|558,558|560,563|596,597|614,614|618,619|626,626|642,643|645,645|689,689|692,692|696,696|699,700|703,703|707,708|714,714|717,719|729,730|732,732|744,744|752,752|756,757|759,759|761,764|766,766|807,807|809,811|813,813|815,816|820,820|823,823|841,841|844,846|848,848|851,852|855,856|862,862|869,870|878,881|885,887|890,893|907,908|912,914|916,916 EEEEEEE?SGGG-----------G--??-----SS------------------------------------------S------S?----------------HHHH-H-HHHH---------HHH---HH----------T---?---------S-S?-----EE------E-E--EEES---------S-------S--------------E-----------------E------E----E------------E------------------E--------E----E-----------S----?----H--HHH-----HHH-----H--HT------??GG-G----------------------------------??--S------?----S----------??----HH---H-HH-------------------------------------HH--HH----T-TS------------------------------------?--S---?--S----------------------------S??---E-E-E-EEEE--?-------?---------------------TT??--------------S?--HH------H---------------HH-H-------------------------------------------H--H---H--TT--T---EE-----E--EEE---------EE-S----------?T-------T?--EE?B?TTSS?B?---------------------------------------B?TTS?B?EE???H--H-----------------H--HHH-H--HH--HT-----E------EE-------EEEE--?SSS--HHHH-------------HH---HHH-H 3HRZ|D PF13520.1_AA_permease_2_seed 61 1066 !Q:0,1|11,15|18,18|20,30|32,37|39,40|42,42|44,46|48,58|62,65|69,69|71,72|79,79|87,88|96,96|100,101|103,104|107,108|114,114|121,126|130,133|135,150|155,159|167,168|175,176|179,179|182,184|186,186|188,191|194,194|199,199|201,202|206,208|210,213|215,215|217,231|236,301|304,305|308,308|313,316|330,330|335,335|340,340|343,343|351,351|365,369|372,375|377,407|409,411|413,431|433,439|443,447|450,454|456,465|467,469|471,481|483,483|485,488|491,496|498,499|510,528|535,537|540,546|550,551|553,553|559,564|578,591|596,597|601,601|604,604|606,606|609,620|622,622|626,627|631,633|635,651|653,653|661,662|666,667|669,670|678,678|684,689|694,697|711,711|717,726|728,728|730,737|741,758|760,761|763,773|791,791|798,834|838,841|843,844|848,863|875,877|884,884|890,892|896,898|901,909|912,919|922,934|936,937|940,953|960,960|966,970|975,976|980,983|985,991|996,1016|1018,1019|1021,1028|1030,1035|1038,1041|1044,1044|1048,1056|1059,1059|1063,1063 Q:2,10|16,17|19,19|31,31|38,38|41,41|43,43|47,47|59,61|66,68|70,70|73,78|80,86|89,95|97,99|102,102|105,106|109,113|115,120|127,129|134,134|151,154|160,166|169,174|177,178|180,181|185,185|187,187|192,193|195,198|200,200|203,205|209,209|214,214|216,216|232,235|302,303|306,307|309,312|317,329|331,334|336,339|341,342|344,350|352,364|370,371|376,376|408,408|412,412|432,432|440,442|448,449|455,455|466,466|470,470|482,482|484,484|489,490|497,497|500,509|529,534|538,539|547,549|552,552|554,558|565,577|592,595|598,600|602,603|605,605|607,608|621,621|623,625|628,630|634,634|652,652|654,660|663,665|668,668|671,677|679,683|690,693|698,710|712,716|727,727|729,729|738,740|759,759|762,762|774,790|792,797|835,837|842,842|845,847|864,874|878,883|885,889|893,895|899,900|910,911|920,921|935,935|938,939|954,959|961,965|971,974|977,979|984,984|992,995|1017,1017|1020,1020|1029,1029|1036,1037|1042,1043|1045,1047|1057,1058|1060,1062|1064,1065 ??HHHHHHHHG-----GG-S-----??---?T------T--S-G---G-----------GST----TGG-G--HHHHHH-HHHHHTH--HHHHHHH-HHH--H--SB--TTTSS?SSSHHH------HHH----T-----------?----HHHH-----HHHHTTT--THHHHH--HH-HH---H-H----HH-HHHH-H--HHH---T----T?T---------------TTTS-?----------------------------------------------------------------HH--HH-HHHH----HHHHHHHHHHHHS?TTSH-HHHH-HH-HHHHTTH-HHHHHHHHHHHHH-----HH----S--?????--------------------????S---S?-----------------?S??-----TTS-----TT-----S----------G---G-----------G-H----HH------H--HHHHTTTTTT-------------------SGGGTT---SS------?HHH--H-HHHHH------HHHHHHHHHHHHH--------------HHHH--HHH-HS?G-GG-?--------?-S-SSH--HHH---H-----------------H-HHHHHHH-?GGG--T--THHHHHH-HHHHH------HHHH----HHHHHTTHHHHHT?HHHHT----------S?S?-------SSS???-------------?-S--S??--------?HHHHHHHHHHHHHHHTT-TTTTSS-------------------------------------SSH----H--HHH----------------HHHHHHHHHHH---HHHHHH-HHHHH---HHH---HH---??----SS-------?BS-------------S??SS-?------------HHHHHH-HHHHH-----HHHH--HHH----H-------HHTT-----------??-------?S-?S--------S------SS??--SS-HHH---------HH-HHH-HH 3GIA|A PF13521.1_AAA_28_seed 115 352 !Q:5,6|14,17|20,23|27,32|34,41|43,43|45,52|55,56|58,60|63,66|77,81|84,84|86,90|94,99|102,118|125,125|128,130|135,135|138,138|140,143|145,146|148,148|150,159|161,165|174,174|181,181|183,184|186,186|190,190|193,227|229,230|232,236|239,239|241,248|252,255|258,263|271,305|307,307|312,312|319,322|327,330|333,336|341,344|348,348 Q:0,4|7,13|18,19|24,26|33,33|42,42|44,44|53,54|57,57|61,62|67,76|82,83|85,85|91,93|100,101|119,124|126,127|131,134|136,137|139,139|144,144|147,147|149,149|160,160|166,173|175,180|182,182|185,185|187,189|191,192|228,228|231,231|237,238|240,240|249,251|256,257|264,270|306,306|308,311|313,318|323,326|331,332|337,340|345,347|349,351 EEEEE??TTSHHHH----HH----HHH------H--------H-H--------TT-?E---EE--??TTHHHHHHSS-----SS?T-----TSS?-----TT-----------------THHHHH-HH---HHHH-HH-H----H--H-H----------H-?---SSEEEESS?HHHHHH-H--H-HHH-HS----------------------------?----??H--H-----HH-H--------HHH----HS?-?---SEEEEEE?-?-??------??-----????-?--?-????-?S-HHHH-HHHHHH----HHHG----GG?-??EEEE--?-SSH-HHH 3UWK|A PF13522.1_GATase_6_seed 67 226 !Q:6,7|10,12|14,19|21,41|48,48|50,52|54,54|57,58|60,62|66,67|69,69|73,77|79,81|94,97|106,107|110,114|116,118|126,126|129,132|137,144|149,149|151,160|162,163|165,165|175,175|184,184|186,186|189,199|201,202|207,207|209,216|218,219 Q:0,5|8,9|13,13|20,20|42,47|49,49|53,53|55,56|59,59|63,65|68,68|70,72|78,78|82,93|98,105|108,109|115,115|119,125|127,128|133,136|145,148|150,150|161,161|164,164|166,174|176,183|185,185|187,188|200,200|203,206|208,208|217,217|220,225 BTEEEE--EE--?S------S---------------------EEEEEE-E???S?TT--T??-SSE--E?TTS?----E---EEEEEEEETTHH----HHHHHHTT--TS?--??S-??TTHHHHH-HH----HHHT--------TTTG-G----------G??E-EEEEEEEET-TTTEEEEE-E?TT------?---?S??EEEE?T--------T??EEEESS 3OOJ|A PF13523.1_Acetyltransf_8_seed 54 268 !Q:3,7|11,11|14,14|27,28|31,31|33,39|42,42|46,46|49,49|53,53|57,61|70,79|84,86|91,99|102,106|109,113|122,124|129,163|165,168|170,170|175,176|180,181|185,185|187,188|203,205|210,210|212,213|216,216|218,219|224,225|229,229|241,243|250,250|252,256|258,259|261,261|265,265 Q:0,2|8,10|12,13|15,26|29,30|32,32|40,41|43,45|47,48|50,52|54,56|62,69|80,83|87,90|100,101|107,108|114,121|125,128|164,164|169,169|171,174|177,179|182,184|186,186|189,202|206,209|211,211|214,215|217,217|220,223|226,228|230,240|244,249|251,251|257,257|260,260|262,264|266,267 EEE??---GGG-HH-HHHHHTTSTTTH--HH-H-??-???HH-HHH-HH-HHH-HHT----?TTEEEEEE----------EETT---EEEE---------EE-----EE-----EEGGGSGG---GGGS---------------------??---------?--T----T?EEEE--EEE?-SGG-G--SSSSTHHHHHHHHH---HHHH-T--ST-T??EEEE??BTT?HHHHHHHHHTT-?-EEEEEE-E-?---S--S?EEE-EE 2PR8|A PF13524.1_Glyco_trans_1_2_seed 238 205 !Q:1,1|3,18|25,53|55,60|62,66|76,78|83,83|85,94|101,102|104,107|110,128|130,131|136,136|138,138|140,140|149,149|154,155|157,158|160,160|162,162|164,164|167,167|170,170|179,179|182,182|185,188|197,198 Q:0,0|2,2|19,24|54,54|61,61|67,75|79,82|84,84|95,100|103,103|108,109|129,129|132,135|137,137|139,139|141,148|150,153|156,156|159,159|161,161|163,163|165,166|168,169|171,178|180,181|183,184|189,196|199,204 E-E??------------??BGGGTB?-------------------------??-S?-----H-----HHHHHHHTT?-?EEEE-S----------STTGGG--G--??TT-------------------T--EEEE?T-T?HHHHHHHH-HHHH--T-?H-H-H-HH-HH-HHHHHHHH-HH-HT----BHHHHHHH--HHHHHH 3S28|A PF13525.1_YfiO_seed 30 246 !Q:0,3|19,19|34,36|39,39|58,58|73,73|76,76|96,137|141,145|159,159|195,195|211,211|219,219|233,233|236,236|242,242|246,246 Q:4,18|20,33|37,38|40,57|59,72|74,75|77,95|138,140|146,158|160,194|196,210|212,218|220,232|234,235|237,241|243,245 ????HHHHHHHHHHHHHTT?HHHHHHHHHHHHHH--?TT?TTHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHH?TT?TTHHHHHHHHHHHHHHHHT?????----------????-------????---???------HHH-----HHHHHHHHHHHHH?TTSTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHS?SSHHHHH-HHHHHHHHHHHTT?HH-HHHHH-HHH- 2XEV|A PF13527.1_Acetyltransf_9_seed 105 186 !Q:4,6|10,11|23,26|33,35|38,38|40,40|55,60|62,64|66,68|70,70|77,81|85,88|103,103|106,106|112,112|121,121|127,130|132,132|134,137|153,153|155,156|161,165|167,168|170,172|176,176|181,182 Q:0,3|7,9|12,22|27,32|36,37|39,39|41,54|61,61|65,65|69,69|71,76|82,84|89,102|104,105|107,111|113,120|122,126|131,131|133,133|138,152|154,154|157,160|166,166|169,169|173,175|177,180|183,185 EEEE??-GGG--HHHHHHHHHHH????HHHHHH---TT?S-SHHHHHHTTHHHHH------H---S---E-EEEEEE-----TTE----EEEEEEEEEEEEEE-TT-EEEEE-EEEEEEEE?GGGTT----S?H----HHHHHHHHHHHHHHT-T??EEEE??---S?-H---HHH-HHTT-?EEE 2JDC|A PF13528.1_Glyco_trans_1_3_seed 39 469 !Q:0,0|7,7|9,9|11,14|32,33|35,39|45,45|48,48|51,51|53,53|57,59|62,62|64,67|69,77|79,79|82,93|96,99|102,106|109,117|119,120|126,127|129,130|133,133|145,145|148,149|153,156|163,163|168,177|186,190|195,196|199,199|203,203|207,210|214,214|216,216|219,224|226,228|231,234|241,243|251,251|254,268|271,271|273,273|277,278|286,293|295,296|298,299|302,302|307,307|311,312|314,314|327,327|330,333|335,335|341,341|344,354|357,364|377,377|384,385|387,387|397,399|411,412|416,422|425,425|443,444|448,449|460,468 Q:1,6|8,8|10,10|15,31|34,34|40,44|46,47|49,50|52,52|54,56|60,61|63,63|68,68|78,78|80,81|94,95|100,101|107,108|118,118|121,125|128,128|131,132|134,144|146,147|150,152|157,162|164,167|178,185|191,194|197,198|200,202|204,206|211,213|215,215|217,218|225,225|229,230|235,240|244,250|252,253|269,270|272,272|274,276|279,285|294,294|297,297|300,301|303,306|308,310|313,313|315,326|328,329|334,334|336,340|342,343|355,356|365,376|378,383|386,386|388,396|400,410|413,415|423,424|426,442|445,447|450,459 ?EEEEEE?S-S----HHHHHHHHHHHHHHHTT--T--?--EEEEE?TT-ST-H-HHH---TG-G----G---------T?EE------------EE??-?GG-----GS---------S??SHHHH--H?-TH-HHHHHHHHHHH-HH--HHH?--?SEEEEE-ESTT----------HHHHHHHH-----HHTT??EE-EEE?SSS??--HHH-H-HH------G---GG---?SEEEES---STTSSTT?EE???--------???-HH-H-HTS??HHHHTTT?----?--S--S--EE-EEEE?TTT??H-HHHHHHHHHHHH-HG----G-GEEEE-EE?-----?----TT?-------HHHHHHHHHHTT?TTSEES??S?HHHHHHEEE???HHHHHHHHHHT??EEE????-?-TT?HHHHHHHHHHHTTSEEE??GGG??HHHHHHHHHT?-------? 2IYA|A PF13529.1_Peptidase_C39_2_seed 127 261 !Q:3,7|9,14|16,17|19,35|38,40|51,55|59,62|64,73|81,82|84,87|90,90|94,101|106,107|115,115|118,120|124,128|130,134|136,136|140,140|143,143|147,147|150,150|152,157|163,163|167,167|169,174|179,179|185,186|188,189|200,202|206,206|216,216|220,220|222,226|237,237|239,244|247,253|258,258 Q:0,2|8,8|15,15|18,18|36,37|41,50|56,58|63,63|74,80|83,83|88,89|91,93|102,105|108,114|116,117|121,123|129,129|135,135|137,139|141,142|144,146|148,149|151,151|158,162|164,166|168,168|175,178|180,184|187,187|190,199|203,205|207,215|217,219|221,221|227,236|238,238|245,246|254,257|259,260 TTS?????T------T--T----------------?TT?--HHHHHHHHHH-----HHT----T?---?---??HHHHHHH--S-?--EE?SEE--------TTEE??TTTSEEB?SS?--TTS?----B?-???H-HHH-HH-HHH-HH?T------TTEEE?TTS?H------HHHH-HHHHT--T??EEEEEETTSS???GGG?EEEEETTEE-EEE?T-----TEEEEEEEEE?S------SE-------EEEE?TT 2BU3|A PF13530.1_SCP2_2_seed 41 317 !Q:6,8|16,16|18,35|39,45|47,49|55,55|59,59|71,80|110,110|115,115|120,122|124,126|130,131|136,141|144,154|156,157|159,160|162,163|165,166|180,195|197,197|206,207|210,210|213,217|219,219|227,227|231,231|238,254|272,272|283,283|285,289|291,291|293,293|302,302|305,307|309,316 Q:0,5|9,15|17,17|36,38|46,46|50,54|56,58|60,70|81,109|111,114|116,119|123,123|127,129|132,135|142,143|155,155|158,158|161,161|164,164|167,179|196,196|198,205|208,209|211,212|218,218|220,226|228,230|232,237|255,271|273,282|284,284|290,290|292,292|294,301|303,304|308,308 GGEEEE???HHHHHHH-H-------?---------?SSS?--?---E---EEEEE?TTS?EEEEEEEEEET----------TEEEEEEEEESSHHHHHHHHHHHHTTGGG?SEEE-EEEE-??S?-?SGG--GSSS-?-??-EE-----------E--E--E--E??EEEESSHHHHHHT?-????---------?S?EEEEEEEE-?TT?GG-----G?EEEEEEE?SSS?EEEEES---------????????SEEEEHHHHHHHHHTSS?HHHHHHTTSS-E-----E?H-HHHHHHHH-HS??-S-?-????? 3SXO|A PF13531.1_SBP_bac_11_seed 225 746 !Q:3,4|7,8|13,14|20,20|22,22|24,24|29,29|31,31|33,38|40,43|45,61|63,64|66,67|71,74|77,79|81,85|88,89|93,97|100,110|114,136|141,152|155,155|157,157|163,163|165,165|169,174|176,176|178,178|180,191|194,195|199,200|203,204|206,211|217,217|221,275|277,281|284,291|293,293|295,295|297,306|310,313|315,358|361,362|365,365|367,370|372,376|378,380|385,396|400,400|404,405|407,421|424,449|451,477|483,483|486,486|489,491|493,494|499,518|521,521|526,535|538,538|540,540|542,543|545,549|551,551|553,555|557,557|560,560|562,565|567,570|573,575|578,600|602,611|613,613|615,616|618,618|622,629|633,635|639,641|643,674|676,677|685,686|688,691|693,699|701,707|709,711|714,714|718,721|726,726|729,729|732,732|737,737|739,739|744,744|746,746 Q:0,2|5,6|9,12|15,19|21,21|23,23|25,28|30,30|32,32|39,39|44,44|62,62|65,65|68,70|75,76|80,80|86,87|90,92|98,99|111,113|137,140|153,154|156,156|158,162|164,164|166,168|175,175|177,177|179,179|192,193|196,198|201,202|205,205|212,216|218,220|276,276|282,283|292,292|294,294|296,296|307,309|314,314|359,360|363,364|366,366|371,371|377,377|381,384|397,399|401,403|406,406|422,423|450,450|478,482|484,485|487,488|492,492|495,498|519,520|522,525|536,537|539,539|541,541|544,544|550,550|552,552|556,556|558,559|561,561|566,566|571,572|576,577|601,601|612,612|614,614|617,617|619,621|630,632|636,638|642,642|675,675|678,684|687,687|692,692|700,700|708,708|712,713|715,717|722,725|727,728|730,731|733,736|738,738|740,743|745,745 EEE--EE--EGGG--HHHHH-H-H-HHHH-H-H------H----H?--------?-------E--E--EEE----EE--?H-----HH--HHH-----HH-----------HHT--?-------------??-----SEEE-?----------SS-H-HHHHH-H-HHT------T?B?G------------GG-?EEE--EE--E-?----EEEEE-ESS-?--------------------------------------??????-------?-S-----TT??------H-H-H----------HHT----T-----------------------------?--------?-----EE--EE?T----T-----T--?HHHH------------HHH-HHH--H---------------HT--------------------------T--------------------------?HHHHG-GG-EE---E--ESSH--------------------HH-HHHH----------HH-T-T--S-----S-S---E-EE-E----E----HH---HH-----------------------H----------H?S--S-EEE--------EEE?-?GGG---S--?----------------------------?E--EEEEEEB--T----T?-----?S-------H---HH-HHH----HHHH-TS-HH-HHHH-H-HHTT?E- 1D9Y|A PF13532.1_2OG-FeII_Oxy_2_seed 71 523 !Q:1,1|11,12|14,16|19,20|22,29|31,33|43,46|48,48|51,57|59,61|63,63|65,66|68,70|72,72|74,78|81,90|92,92|94,97|99,101|104,107|113,121|124,134|136,137|139,140|145,148|153,158|165,169|185,204|206,206|208,217|225,226|228,237|239,241|246,250|253,258|262,262|271,271|275,331|334,365|368,369|373,394|400,400|403,403|408,408|411,412|414,415|418,420|424,475|477,477|479,481|483,510|513,513|515,515 Q:0,0|2,10|13,13|17,18|21,21|30,30|34,42|47,47|49,50|58,58|62,62|64,64|67,67|71,71|73,73|79,80|91,91|93,93|98,98|102,103|108,112|122,123|135,135|138,138|141,144|149,152|159,164|170,184|205,205|207,207|218,224|227,227|238,238|242,245|251,252|259,261|263,270|272,274|332,333|366,367|370,372|395,399|401,402|404,407|409,410|413,413|416,417|421,423|476,476|478,478|482,482|511,512|514,514|516,522 T-EEEETTTTT--T---TH--H--------H---HHHHHHHHH----H-HS?----?-B??-B?T--T---S?B-?---SS----------E-E----E---EE----SSBEE---------EE----------?S--S--SEEE----ESEE------TTTTEE?????HHHHHHHHHHHHHTT-------------------?T-T---???---?EEEEEEE?-T----------T?-?EEEE????-SS-----?TTS?EEEEEEES?EEE---------------------------------------------------------EE----?--------------------------?SS--TTS--------------------??EEEEE?TT?EEEE?GG--G--GG??-EEE?????-?--------------------------------------------?B-T---T----------------------------TB-T?EEEEEEE 3H8O|A PF13533.1_Biotin_lipoyl_2_seed 99 108 !Q:0,0|2,11|15,18|20,23|25,26|28,40|43,44|47,47|50,54|56,58|63,70|76,90|94,95|97,103|105,106 Q:1,1|12,14|19,19|24,24|27,27|41,42|45,46|48,49|55,55|59,62|71,75|91,93|96,96|104,104|107,107 ?E----------EEE-?-?S?--?S-?B???------???-SS?-EE?TT?????B??-HHHH--------HHHHH---------------HHH--H-------H--H 2F1M|A PF13534.1_Fer4_17_seed 126 201 !Q:1,9|11,12|16,23|25,36|38,43|45,58|62,72|75,75|77,83|85,91|93,93|97,102|104,105|111,115|120,120|123,127|129,129|133,136|139,139|141,141|143,149|151,152|154,154|156,163|165,170|172,172|174,176|179,183|185,186|189,190|193,193|196,200 Q:0,0|10,10|13,15|24,24|37,37|44,44|59,61|73,74|76,76|84,84|92,92|94,96|103,103|106,110|116,119|121,122|128,128|130,132|137,138|140,140|142,142|150,150|153,153|155,155|164,164|171,171|173,173|177,178|184,184|187,188|191,192|194,195 T????--?--T--TGG--------G-----------?H------H--------------HHH-----------HT-T-------T-------S?HHH------H--HHHHH-----HHHS?TT----?S?HHH----HH-G-G-------G-?S-T--------T------T-T---TT?????H--HH--HH?TT--??? 3AE5|B PF13535.1_ATP-grasp_4_seed 109 273 !Q:3,4|14,14|19,30|35,35|48,55|57,60|69,71|73,77|79,81|84,84|87,89|91,95|103,104|114,118|121,123|126,128|130,130|137,139|141,141|146,146|152,155|166,169|174,174|183,185|189,195|197,198|203,203|205,208|213,214|225,226|231,231|233,236|250,250|253,255|264,264|266,268 Q:0,2|5,13|15,18|31,34|36,47|56,56|61,68|72,72|78,78|82,83|85,86|90,90|96,102|105,113|119,120|124,125|129,129|131,136|140,140|142,145|147,151|156,165|170,173|175,182|186,188|196,196|199,202|204,204|209,212|215,224|227,230|232,232|237,249|251,252|256,263|265,265|269,272 HTT-?HHHHHHHHH-HTTS?-???-------EEEE?SHHHHHHHHHHS?-------S----SEEEEESS?-?T-----T---TT?EE---E?---?TTSHHHH--HHHHHHHHT-----TS???TT???S?SEEEEE???B?HHHH?SSSSS?---SEEEEEEEEE----TTEE-EEEEEEEE???BTT-------B??EEEE-S????HHHH--HHHHHHHHHH--HHHH-T??--SEEEEEEEEEEGG-GE---EEEEEEES-S?-?STTH 3ORQ|A PF13537.1_GATase_7_seed 568 227 !Q:3,12|14,14|18,19|24,31|33,33|36,39|42,43|54,57|63,63|67,68|70,70|72,79|81,91|93,96|101,101|109,125|132,138|141,142|151,152|154,157|159,160|162,163|166,169|176,176|179,180|182,183|188,196|198,202|204,210|212,215 Q:0,2|13,13|15,17|20,23|32,32|34,35|40,41|44,53|58,62|64,66|69,69|71,71|80,80|92,92|97,100|102,108|126,131|139,140|143,150|153,153|158,158|161,161|164,165|170,175|177,178|181,181|184,187|197,197|203,203|211,211|216,226 EEE???-------S?TTT??SSEE--?-----T-TS?---EE--EEEEEEETTH----HHHHH-HHT--T-T--------S---?--?--?-S-?-?TTHH-HHHHHHH-----------------HTTTTG-------GG??EEEEEEEE--E----T--T--TT----EEEEEE?TT??S??EEEE--------?T-----T?-----?E----EEESSGGGTTT 3OOJ|A PF13538.1_UvrD_C_2_seed 132 179 !Q:1,1|4,5|9,38|41,41|43,44|46,48|53,61|68,99|101,103|107,107|113,113|115,115|126,127|136,136|140,142|145,153|155,156|160,163 Q:0,0|2,3|6,8|39,40|42,42|45,45|49,52|62,67|100,100|104,106|108,112|114,114|116,125|128,135|137,139|143,144|154,154|157,159|164,178 E?TT??EEE???????--------------------???TT?B??E---EEEE---------TTEEEE????--------------------------??B???TTG-GGGEE-E?SEEEHHHHTT??EEEEEEEE?GGG---GG---------G??HHH----HHHHHHTEEEEEEEE 1W36|D PF13539.1_Peptidase_M15_4_seed 215 194 !Q:1,3|6,7|13,22|25,25|28,33|35,36|39,47|50,50|55,110|114,115|117,124|132,133|136,137|139,139|144,152|155,158|164,164|166,173|176,180|182,187 Q:0,0|4,5|8,12|23,24|26,27|34,34|37,38|48,49|51,54|111,113|116,116|125,131|134,135|138,138|140,143|153,154|159,163|165,165|174,175|181,181|188,193 S?-?TT--SSGGG----------GT?EE------E--EE---------EE?TTSS--------------------------------------------------------SEE??S--------SSHHHHH--HH--H-HHHH---------TT--?-EEGGG-S--------SS-----S--?--?TTEEES 2VO9|A PF13540.1_RCC1_2_seed 320 72 !Q:1,2|4,5|7,10|13,15|17,20|22,22|25,29|33,33|36,36|38,41|43,43|45,52|58,65|67,68 Q:0,0|3,3|6,6|11,12|16,16|21,21|23,24|30,32|34,35|37,37|42,42|44,44|53,57|66,66|69,71 E--E--E----EE---E--?-S-SE-----EEE-EE-T----T-S?-------EEEEE--?--?--T--TST 4D9S|A PF13541.1_ChlI_seed 173 201 !Q:5,6|9,9|15,22|28,28|30,30|34,34|39,41|45,45|51,59|63,63|67,79|94,99|101,102|104,108|110,112|114,114|116,124|126,127|129,139|141,142|144,146|149,151|153,156|159,159|166,167|169,169|176,179|182,182|184,184|188,191|193,193 Q:0,4|7,8|10,14|23,27|29,29|31,33|35,38|42,44|46,50|60,62|64,66|80,93|100,100|103,103|109,109|113,113|115,115|125,125|128,128|140,140|143,143|147,148|152,152|157,158|160,165|168,168|170,175|180,181|183,183|185,187|192,192|194,200 EEEEE--EE?SSSSB---??---EEEES?B?HHH-HHHH---HHH-HHHHH---------HHH?GGG-------------GGEEEHHHHHHHHH------H--H-----H---H-T---?--?--E--E-----------T--T---EE---E--??EE?TTSBEE??S?HHHHHH----HH-H-HHT-?-?E-EEEEGGG 2X36|A PF13543.1_KSR1-SAM_seed 10 142 !Q:4,4|20,24|26,26|55,55|60,63|69,74|76,76|86,87|95,96|99,99|108,108|119,121|124,126 Q:0,3|5,19|25,25|27,54|56,59|64,68|75,75|77,85|88,94|97,98|100,107|109,118|122,123|127,141 GTTS?STTHHHHHHHHHHHH????-S?HHHHHHHHHHHHHHHHHHGGGTTGGGTS?TTTS---?TTGGG?-----S?STTTHHHHT??HHHHTTS-?TT?SHHHHTTS?HHHHHHHHHT---TT??-THHHHHHHHHHTTGG 2LPE|A PF13545.1_HTH_Crp_2_seed 94 106 !Q:2,2|17,25|28,29|34,35|39,43|54,55|57,57|60,60|76,81|83,87|90,90|92,92|98,98 Q:0,1|3,16|26,27|30,33|36,38|44,53|56,56|58,59|61,75|82,82|88,89|91,91|93,97|99,105 HH-HHHHHHHHHHHHEE---------EE--TTEE--EEE??-??HHHHHHHHTS-?H-HH-HHHHHHHHHHTTSEE------E-----ET-T-EEEES?HHHHHHH 1ZRD|A PF13549.1_ATP-grasp_5_seed 220 397 !Q:5,6|8,11|13,13|15,15|28,34|37,39|42,42|55,59|62,62|69,74|77,100|106,109|115,116|133,134|138,147|149,149|151,182|186,187|191,204|226,227|235,246|252,252|254,265|267,267|273,273|275,275|277,277|284,284|289,303|305,314|326,329|335,339|341,341|346,353|365,369|371,374|376,383|386,386|390,391|397,397 Q:0,4|7,7|12,12|14,14|16,27|35,36|40,41|43,54|60,61|63,68|75,76|101,105|110,114|117,132|135,137|148,148|150,150|183,185|188,190|205,225|228,234|247,251|253,253|266,266|268,272|274,274|276,276|278,283|285,288|304,304|315,325|330,334|340,340|342,345|354,364|370,370|375,375|384,385|387,389|392,396 HHHHT--T--??E-E?HHHHHHHHHTTT????-??EE---ES-SHHHHHHHHHHH---?-SS-EEEEEE?-----TT---??---------?---------HHHHT---?EEEEE?-SHHHHHHHHHHHHHHH--HHH?---------T-T--------------------------??-?-?EEE--EEE?--???-------?EEEEEEEEEETTTEEEEEEEE-?STTHHHH???---------EEEES-S----------??H-HHHHH-H-H-HTSTTH-HHHH-?--???--???---B?---------HHHHHHHHHHH----HHHHH-----H-TTTT--------EEEEEEEEEEE----?B----T--------TS?EEE??EEEEE- 2FPP|B PF13551.1_HTH_29_seed 85 157 !Q:11,18|28,30|43,43|46,55|58,66|68,72|74,76|78,78|84,87|92,92|96,96|98,98|101,105|107,108|110,115|127,129|131,137|141,143|151,156 Q:0,10|19,27|31,42|44,45|56,57|67,67|73,73|77,77|79,83|88,91|93,95|97,97|99,100|106,106|109,109|116,126|130,130|138,140|144,150 HHHHHHHHHTT?------?HHHHHHHHT?-?HHHHHHHHHHHH-HH?-----?---SS?---???--S?????S---S?STHHH----HHHH-TTT-T?TT?---?H--H------HHHHHHHHTSS---S?------STT???HHHHHHH???-?? 2LVS|A PF13554.1_DUF4128_seed 28 137 !Q:14,16|22,24|27,27|30,33|35,35|39,42|51,58|62,68|79,79|83,84|97,98|101,102|105,105|112,113|115,116|118,124 Q:0,13|17,21|25,26|28,29|34,34|36,38|43,50|59,61|69,78|80,82|85,96|99,100|103,104|106,111|114,114|117,117|125,136 HHHHHHHHHHHHHH---HHSTT???EE?TT????S?BTT----BEEEEEEE????????SSS??-????EEEEEEEEEE?SSS??THHHHHHHHHHH??TT??EE?SSSEEE??S??B???????SSEEEEEEEEEE 2L25|A PF13555.1_AAA_29_seed 68 78 !Q:14,14|18,20|25,28|30,31|37,38|54,55|57,58|60,60|63,77 Q:0,13|15,17|21,24|29,29|32,36|39,53|56,56|59,59|61,62 EEEEEEEEETTEEE-EEE?--HHHH----H--HHHHS??SHHHHHHHHHHHHHH--S??T-TT-?--?????-?-??? 3EUJ|A PF13556.1_HTH_30_seed 456 73 !Q:1,1|10,10|14,14|16,16|27,27|44,47|50,52|54,54|58,61|64,64 Q:0,0|2,9|11,13|15,15|17,26|28,43|48,49|53,53|55,57|62,63|65,72 H-HHHHHHHH-HTT-T?HHHHHHHHTS?HHHHHHHHHHHHHHHS-??-TT---S-HHH----HH-HHHHHHHH 3ONQ|A PF13558.1_SbcCD_C_seed 152 128 !Q:9,9|11,12|19,21|29,34|36,36|41,43|45,47|55,55|60,60|76,77|80,92|94,101|108,109|113,113|123,123 Q:0,8|10,10|13,18|22,28|35,35|37,40|44,44|48,54|56,59|61,75|78,79|93,93|102,107|110,112|114,122|124,127 HHHHHHHHT-T?-EEEEEE---TTTTEEE------E-EETT---E---EEEGGGS?HHHH-HHHHHHHHHHHHHHT--TT-------------T------??EEEEES??TTS?HHHHHHHHH-HHHG 3EUJ|A PF13560.1_HTH_31_seed 149 150 !Q:8,8|12,13|16,41|43,46|49,49|57,64|66,67|70,72|80,82|86,99|102,105|112,112|115,115|118,132|137,141|144,144|146,147 Q:0,7|9,11|14,15|42,42|47,48|50,56|65,65|68,69|73,79|83,85|100,101|106,111|113,114|116,117|133,136|142,143|145,145|148,149 HHHHHHHH-HHH--HH--------------------------T-?-?HH-HHHHHTT--------S-?HH---HHHHHHT---TSS--??---------?HH----HHHHHH-HH-HT--?--?---------HHHH-----HH-H--HH 2EWT|A PF13561.1_adh_short_C2_seed 47 383 !Q:0,1|20,20|30,50|70,70|72,85|87,87|89,89|91,94|99,100|102,106|108,113|116,116|123,125|130,135|138,146|152,155|169,175|177,177|184,188|191,195|199,199|203,206|231,232|238,243|251,251|257,259|262,262|281,281|290,291|299,301|303,307|310,311|314,321|325,330|342,345|347,348|367,368|370,370|377,378 Q:2,19|21,29|51,69|71,71|86,86|88,88|90,90|95,98|101,101|107,107|114,115|117,122|126,129|136,137|147,151|156,168|176,176|178,183|189,190|196,198|200,202|207,230|233,237|244,250|252,256|260,261|263,280|282,289|292,298|302,302|308,309|312,313|322,324|331,341|346,346|349,366|369,369|371,376|379,382 ??SSSSSHHHHHHHHHHHTT?EEEEEEEHH---------------------HHHHHHHHHHTTTTSGGGB?T--------------T-S?B?-??SEEE--E-----E?-----TT?SSGGGS--?HHHH------TS---------HHHHH????SHHHHHHHHHHHH-------S?EEEEEE?????TT-----TTS?GGG-?-?HHHHHHHHHHHTHHHHHHHHHHGG--GEEEE------EEEEEEE?GGGTS?-?TT?TTTHHHHHHHHHHHHHHH-HHHHHHHH??EEEEEEE???B-???-SS??SH--------HHH------HHHHHHHHSSS??-?B-?HHHHHHHHHHHHSGGGTT??S-EEEEES--TTGG 1NXQ|A PF13563.1_2_5_RNA_ligase2_seed 139 400 !Q:0,1|8,9|15,31|35,35|38,40|45,51|53,53|55,56|59,59|62,63|68,91|104,155|157,162|165,165|169,170|176,176|179,185|187,190|196,223|237,249|252,252|254,283|285,288|292,296|299,299|301,302|307,341|349,370|374,376|379,382|386,388|396,396 Q:2,7|10,14|32,34|36,37|41,44|52,52|54,54|57,58|60,61|64,67|92,103|156,156|163,164|166,168|171,175|177,178|186,186|191,195|224,236|250,251|253,253|284,284|289,291|297,298|300,300|303,306|342,348|371,373|377,378|383,385|389,395|397,399 ??HHHHHH--HHHHH-----------------HHH?GG---GGTS?------S?B??SS?EE??GGGH------------------------HHHHHHHHHHHH----------------------------------------------------T???---EE-EEE--EEEEE?TT-------T??-?EEEEE-------------------------???HHHHHHHHHTTSG-------------GG?S???---------------------------S????EEE-----EE?S??HHHH-----------------------------------HHHHHHH----------------------TTS???EE----EEE?--EEEEEEE?TTS 1IUH|A PF13570.1_PQQ_3_seed 1244 133 !Q:0,2|5,9|13,35|38,38|40,42|46,46|49,49|51,65|68,69|71,75|77,79|81,84|86,90|95,95|97,111|117,117|119,119|121,122|124,127|130,131 Q:3,4|10,12|36,37|39,39|43,45|47,48|50,50|66,67|70,70|76,76|80,80|85,85|91,94|96,96|112,116|118,118|120,120|123,123|128,129|132,132 ?-?EE-----EEE-----------??---?--?--?GG-G---GGG?TT?S???----------??EE--E-----B---T----E-----EEEE?T---------------TSEEE-E-E--E----TT--T 3Q7M|A PF13574.1_Reprolysin_2_seed 49 385 !Q:21,22|24,32|34,34|38,47|50,50|52,53|55,67|69,69|74,76|78,78|80,86|89,96|99,99|103,117|120,120|126,127|139,139|144,144|147,151|161,166|170,174|178,181|185,194|196,196|202,213|216,220|224,224|228,230|233,240|243,251|253,253|260,267|274,275|287,291|293,307|309,310|313,319|321,321|323,336|341,343|346,348|351,354|356,356|358,360|366,367|370,371|378,378|383,383 Q:0,20|23,23|33,33|35,37|48,49|51,51|54,54|68,68|70,73|77,77|79,79|87,88|97,98|100,102|118,119|121,125|128,138|140,143|145,146|152,160|167,169|175,177|182,184|195,195|197,201|214,215|221,223|225,227|231,232|241,242|252,252|254,259|268,273|276,286|292,292|308,308|311,312|320,320|322,322|337,340|344,345|349,350|355,355|357,357|361,365|368,369|372,377|379,382|384,384 HHHHHHHHHHHHHHHHHHHHT??T---------T-SSS--???----?EE-E--E-------------E-EEEE-??S?B?----??TT??-----?TT-BSS?--------------SS?TTSSS??HHHHHHHHHHH-HHHH-HT-----TSSEEEEEE????--GGG??---EEE????SST----------T?SSSSS?--??-------EE?----TTT?SEE???EE--------EE---------E?EETTEE??------HHHHHH--HHHHHHHHHTT?????S---------------S-?TT-------T-S--??----------GGGT???TT-?-SS??-?S?S---TTTTS??HH--HHHHHH-HHHH-H 1BKC|A PF13576.1_Pentapeptide_3_seed 230 73 !Q:3,3|6,6|9,12|14,14|16,19|21,21|26,31|33,36|40,40|44,47|49,49|51,51|53,53|56,56|58,58|60,62|64,66 Q:0,2|4,5|7,8|13,13|15,15|20,20|22,25|32,32|37,39|41,43|48,48|50,50|52,52|54,55|57,57|59,59|63,63|67,72 EES?EE-ES?---B?T----T?EEET?-----E----EEE-EEE----E-S?B?TT?B?T---T--?EEEEEE 2XT4|A PF13577.1_SnoaL_4_seed 175 375 !Q:21,30|32,42|44,46|48,55|57,60|63,63|65,65|67,67|70,72|74,78|82,82|85,87|89,89|92,114|116,116|120,128|130,131|133,142|151,168|170,170|172,182|186,196|199,209|212,213|217,217|222,222|224,224|226,241|243,250|252,252|255,256|263,263|266,272|276,276|279,281|283,301|303,303|305,309|313,313|316,317|320,321|324,330|332,332|336,337|344,356|359,360|362,367 Q:0,20|31,31|43,43|47,47|56,56|61,62|64,64|66,66|68,69|73,73|79,81|83,84|88,88|90,91|115,115|117,119|129,129|132,132|143,150|169,169|171,171|183,185|197,198|210,211|214,216|218,221|223,223|225,225|242,242|251,251|253,254|257,262|264,265|273,275|277,278|282,282|302,302|304,304|310,312|314,315|318,319|322,323|331,331|333,335|338,343|357,358|361,361|368,374 HHHHHHHHHHHHHHHHHHHHH----------H-----------T--?H--------H----HH-H-T-TB--?S--?--TTS?EE---S-SS------------?----------E-ESS---------H--H----------HHHHHHHH------------------H-S--?--------TTE-----------EE-----------EE--EEE-EEEE-E-E----?-----------S--------S-SE--EEEEEE-EE-------EEE-EE-?-S-------------------S-T-----TTT-EE--EE--EE-------E-EEE--EEEEEE-------------TT--E------EEEEEEE 1OHS|A PF13578.1_Methyltransf_24_seed 204 439 !Q:5,6|17,19|21,29|31,32|34,80|83,84|86,95|99,108|111,155|159,160|164,201|203,224|227,227|230,236|238,247|252,260|263,263|265,284|287,294|296,296|299,306|310,331|335,335|338,341|343,343|345,355|362,373|375,384|386,388|390,392|397,398|400,402|406,408|410,411|413,414|416,416|418,418|420,420|422,422|424,425|427,431|437,437 Q:0,4|7,16|20,20|30,30|33,33|81,82|85,85|96,98|109,110|156,158|161,163|202,202|225,226|228,229|237,237|248,251|261,262|264,264|285,286|295,295|297,298|307,309|332,334|336,337|342,342|344,344|356,361|374,374|385,385|389,389|393,396|399,399|403,405|409,409|412,412|415,415|417,417|419,419|421,421|423,423|426,426|432,436|438,438 EEEES??SHHHHHHHHT---S--------?T--T--?--------------------------------------------EE--E----------EEE?-------??SS-----------------------------------???-------SHH--HHH--------------------------------------H----------------------TT?TT-------T----------EEEE---------ES?H--------------------HH--------H-HH--------HHH----------------------HHH?SS?---E-E-----------EEEEES--------?---G----------G---G---HHHH--H---HHH---H--H--H-E-E-E-E--E-----EEEEE?S 3OZS|A PF13579.1_Glyco_trans_4_4_seed 231 711 !Q:7,7|13,13|17,19|21,23|25,25|27,31|33,36|39,40|42,44|46,47|49,61|63,70|73,99|101,104|106,113|116,122|127,135|137,140|142,142|144,147|149,149|151,160|162,162|164,177|179,188|190,192|195,207|209,214|218,218|220,220|222,228|230,242|244,244|246,253|256,256|258,280|282,285|287,287|289,305|308,311|313,330|332,346|349,349|351,371|373,375|377,380|383,383|385,388|390,390|392,393|395,397|399,400|402,407|409,411|413,416|420,423|425,427|429,429|431,440|442,443|446,452|454,455|457,468|470,477|480,482|484,511|513,543|545,553|556,591|593,601|604,606|608,613|615,616|618,623|625,631|633,633|635,639|642,647|653,655|657,659|661,666|672,672|677,678|681,682|685,685|689,699|702,702|707,710 Q:0,6|8,12|14,16|20,20|24,24|26,26|32,32|37,38|41,41|45,45|48,48|62,62|71,72|100,100|105,105|114,115|123,126|136,136|141,141|143,143|148,148|150,150|161,161|163,163|178,178|189,189|193,194|208,208|215,217|219,219|221,221|229,229|243,243|245,245|254,255|257,257|281,281|286,286|288,288|306,307|312,312|331,331|347,348|350,350|372,372|376,376|381,382|384,384|389,389|391,391|394,394|398,398|401,401|408,408|412,412|417,419|424,424|428,428|430,430|441,441|444,445|453,453|456,456|469,469|478,479|483,483|512,512|544,544|554,555|592,592|602,603|607,607|614,614|617,617|624,624|632,632|634,634|640,641|648,652|656,656|660,660|667,671|673,676|679,680|683,684|686,688|700,701|703,706 SHHHHHH-HHHHH-HHH---H---T-T--?--E----EE--E---E--E-------------E?-?----?GG---------------------------G?---S--------EE-------EEET---------T----E-E----E-E----------E-E------?------?S---------?S---SS??-----------G------GGG-G-G-------G-------------H-H--------HH-H-----------------------H----H-H-----------------HH----H------------------H---------------HH-T---------------------T???S----EE-E----E-E--H---H--H------H---H----HHH----H---H-H----------H--HH-------H--T-------??---E--------EE---E?---------------------------S-------------------------------S--------?TT??--?????-------?----?------------??H---------HH---H------H--H------H-------H-H-----HH------HHHTT--?S---E------EEESS-HHHH--HH--HH-HHH--?----?--?TT-SEEE???? 3FRO|A PF13580.1_SIS_2_seed 65 186 !Q:6,6|14,14|18,25|42,43|47,48|55,55|71,75|77,77|83,85|93,95|97,98|100,104|106,106|114,116|123,123|128,129|132,139|142,142|148,149|152,153|155,160|171,173|178,178|185,185 Q:0,5|7,13|15,17|26,41|44,46|49,54|56,70|76,76|78,82|86,92|96,96|99,99|105,105|107,113|117,122|124,127|130,131|140,141|143,147|150,151|154,154|161,170|174,177|179,184 HHHHHH-HHHHHHH-HHH--------SHHHHHHHHHHHHHHH--HTT??EEEEES-GGGHHHHHHTSSSTT----?B-TTEEE???GGGSSSS---S--T-----T-HHHHHTT?--TTHHHH-HHHH--TT----?--?TT?EEEEE-?SS??S------HHHHHHHHHH---HHHT?EEEEEE? 1TK9|A PF13581.1_HATPase_c_2_seed 142 258 !Q:3,3|6,6|11,11|20,20|22,23|26,26|28,30|36,43|64,64|66,66|68,82|86,102|106,125|133,136|140,141|143,150|154,155|158,159|161,161|164,164|168,212|214,214|227,228|231,239|242,242|247,249 Q:0,2|4,5|7,10|12,19|21,21|24,25|27,27|31,35|44,63|65,65|67,67|83,85|103,105|126,132|137,139|142,142|151,153|156,157|160,160|162,163|165,167|213,213|215,226|229,230|240,241|243,246|250,257 EES?TT-HHHH-HHHHHHHH-H--GG-G???HHHHH--------HHHHHHHHHHHHHHHTTSTT?T-T---------------SEE-----------------EEE--------------------EEEETTE----EEE--E--------EEE-?SS??S?HH-HHT???????--------------------------------??????S?HHHHHHHHSSEE--EE---------EE-ETTT---EEEEEEEE 3ZXO|A PF13582.1_Reprolysin_3_seed 94 249 !Q:16,18|22,25|32,35|40,46|50,58|60,64|66,70|74,91|97,97|100,102|106,106|110,117|124,125|128,128|134,141|143,155|158,158|163,163|165,174|176,176|179,179|183,197|199,199|204,208|210,210|213,213|217,232|245,248 Q:0,15|19,21|26,31|36,39|47,49|59,59|65,65|71,73|92,96|98,99|103,105|107,109|118,123|126,127|129,133|142,142|156,157|159,162|164,164|175,175|177,178|180,182|198,198|200,203|209,209|211,212|214,216|233,244 HHHHHHHHHHHHHHHG---GGT----EEEEEE----EEEE------?SSS-------?-S-----S???--SSH------------------HHHHH-HH---HHH-HHH--------THHHHS??SE-EEEEE????----S-------------TT?SEEE?T----------T?TT?TTT?--------------E-EEEE-??-?S?HH-HHH----------------HHHHHHHHHHTT???? 1BKC|A PF13583.1_Reprolysin_4_seed 9 321 !Q:0,3|11,11|17,17|19,24|44,44|46,64|80,81|84,86|88,89|92,92|95,103|107,107|113,113|120,125|128,129|137,141|145,147|151,152|155,155|158,165|169,169|172,175|180,209|212,216|223,223|235,239|242,251|256,256|258,258|260,260|263,270|273,277|279,283|293,295|302,304|308,311|313,315|320,320 Q:4,10|12,16|18,18|25,43|45,45|65,79|82,83|87,87|90,91|93,94|104,106|108,112|114,119|126,127|130,136|142,144|148,150|153,154|156,157|166,168|170,171|176,179|210,211|217,222|224,234|240,241|252,255|257,257|259,259|261,262|271,272|278,278|284,292|296,301|305,307|312,312|316,319 ----EEEEEEE?TTTTT-T?----?TTHHHHHHHHHHHHHHHHH-G-------------------GGTEEEEEEEEEESS??SS???S-?HH-HH---------HHH-HHHHH-HHTHHH------HS??SEEEEEE???-?GGG?-?EEE-?TT?TT-------?TTT-SE----EEEE?----------------------------?TT?----HHHHHH-HHHHHHHHTTT?????TT???-------TTSS?T-T?SS------??SS??---S???--HHHHHHHHH---HHHTSS???GGG?--?S???TTSS? 1O0Q|A PF13585.1_CHU_C_seed 160 127 !Q:1,1|3,4|6,6|9,10|12,12|17,17|19,20|25,25|27,29|32,32|34,35|37,38|41,41|48,48|52,52|57,64|69,69|71,72|75,82|86,86|88,89|100,103|110,116|118,119 Q:0,0|2,2|5,5|7,8|11,11|13,16|18,18|21,24|26,26|30,31|33,33|36,36|39,40|42,47|49,51|53,56|65,68|70,70|73,74|83,85|87,87|90,99|104,109|117,117|120,126 S?B?-E-EE??S-SSSS-S??BEEE-E--?BS-S-?E--EE-EEEEEE?TTS?EEEE????????BGGG?B-?SB---?----TTS?B??SEEEEEEEEE----EESSTT?----??E--EEEEEEE 1XF1|A PF13587.1_DJ-1_PfpI_N_seed 59 42 !Q:0,0|7,10|15,15|18,21|23,24|26,26 Q:1,6|11,14|16,17|22,22|25,25|27,41 ?EEEEEE????EEET-TE----E??B?HHHHHHHHHHHHHTT 1QVV|A PF13588.1_HSDR_N_2_seed 81 187 !Q:0,11|19,24|27,27|33,34|36,36|38,40|42,51|53,55|57,61|67,68|73,87|89,91|99,100|104,104|106,107|110,112|114,115|123,123|126,126|128,129|131,133|135,135|142,142|145,145|151,156|158,160|163,176|181,182|185,186 Q:12,18|25,26|28,32|35,35|37,37|41,41|52,52|56,56|62,66|69,72|88,88|92,98|101,103|105,105|108,109|113,113|116,122|124,125|127,127|130,130|134,134|136,141|143,144|146,150|157,157|161,162|177,180|183,184 ----------?-EEEEEEE???-??EE-EETTE--E-E---E?-??-----?E---E-----EEEEE--EETT---------------E---EEEEEEE??TTS?G--GG---S--HHHHHHH-HH-H--H---T?SEEEEE?SS?EEEEE------T---TT---?-------?--EEEE--SS?? 3H1T|A PF13589.1_HATPase_c_3_seed 55 299 !Q:2,2|18,24|27,33|50,51|58,64|67,67|69,70|72,92|99,99|101,104|107,108|110,112|115,115|117,118|122,126|128,130|132,134|137,137|139,140|142,144|154,160|162,166|173,181|185,185|187,191|207,208|210,213|215,217|220,221|224,225|228,229|232,238|240,242|245,248|252,253|255,257|261,262|266,293|296,296 Q:0,1|3,17|25,26|34,49|52,57|65,66|68,68|71,71|93,98|100,100|105,106|109,109|113,114|116,116|119,121|127,127|131,131|135,136|138,138|141,141|145,153|161,161|167,172|182,184|186,186|192,206|209,209|214,214|218,219|222,223|226,227|230,231|239,239|243,244|249,251|254,254|258,260|263,265|294,295|297,298 GG-GTTHHHHHHHHHHHH-------HH-------HHHHHHTSSSGGGGTT??EEEEEE-------TT-T--T---------------------EEEEEE?S????HH--H---HH-H--HTT-----S-??H---HH-H--H---HHHHHTTSH-------H-----HHSGGG---------GTT-S??-?-GGGGGGTEEEEEEEE--E---?T---TS-?GG--GE--EE-------E---EE---?SSS--E---EEE--EEE??--------------------------SS?EE 1UYH|A PF13590.1_DUF4136_seed 166 409 !Q:0,9|12,17|19,20|23,25|29,33|36,43|45,45|47,51|53,57|62,62|65,66|70,71|76,76|78,81|83,92|97,98|113,113|115,115|118,124|129,132|134,136|147,149|151,157|162,177|179,185|187,198|201,206|208,210|212,220|224,227|230,236|238,238|241,242|244,252|255,270|274,279|281,306|308,311|314,315|323,330|334,348|352,352|357,357|365,372|374,374|376,378|380,381|388,390|394,396|405,405|408,408 Q:10,11|18,18|21,22|26,28|34,35|44,44|46,46|52,52|58,61|63,64|67,69|72,75|77,77|82,82|93,96|99,112|114,114|116,117|125,128|133,133|137,146|150,150|158,161|178,178|186,186|199,200|207,207|211,211|221,223|228,229|237,237|239,240|243,243|253,254|271,273|280,280|307,307|312,313|316,322|331,333|349,351|353,356|358,364|373,373|375,375|379,379|382,387|391,393|397,404|406,407 ??????????SS------E--EE---EEE----?TT?------?G-G-----G---??EEEE?SS-?EEE?-SSSS?E----E?---?-----SHHH--HHHHHHHHHHHHHT-T?EE------?SSTT----T-?-SEEEEEEEES??-T-------TTTT------------?-?-S-------S------------SG------G---G---------GST----TS??-----H-HH--H---------SS??--------------EEE?-?---S?--?------------???---?--?S----SE--EEEEEEE--------TTS--?---------?--STT?EEEE-EEEEEEE??-??---S-H---H--HHHTTH---HHH---HHHHHHHT?TT? 4F54|A PF13591.1_MerR_2_seed 56 97 !Q:1,1|10,12|25,25|27,29|33,33|35,36|39,43|45,47|49,49|55,55|68,70|97,97 Q:0,0|2,9|13,24|26,26|30,32|34,34|37,38|44,44|48,48|50,54|56,67|71,96 B?HHHHHHHH???HHHHHHHHHTTS-S??-SSS-S--SS-----S??-B?HHHHH-HHHHHHHHHHHH???HHHHHHHHHHHHHHHHHHHHHHHHHH- 3UCS|A PF13593.1_DUF4137_seed 59 534 !Q:16,16|19,20|22,32|39,40|47,48|59,60|91,91|98,100|102,141|144,148|160,160|162,162|168,168|175,176|200,200|204,204|206,219|221,235|241,249|273,275|278,279|281,281|283,285|287,309|314,315|317,317|320,320|322,331|336,339|349,349|356,363|369,370|392,395|403,403|405,435|437,460|472,472|474,474|476,480|487,488|495,495|497,497|499,507 Q:0,15|17,18|21,21|33,38|41,46|49,58|61,90|92,97|101,101|142,143|149,159|161,161|163,167|169,174|177,199|201,203|205,205|220,220|236,240|250,272|276,277|280,280|282,282|286,286|310,313|316,316|318,319|321,321|332,335|340,348|350,355|364,368|371,391|396,402|404,404|436,436|461,471|473,473|475,475|481,486|489,494|496,496|498,498|508,533 HTHHHHHHHHHHHHHH?GG--G-----------TGGGGG--GHHHHH--HHHHHHHHHT??GGGGHHHHHSHHHHHHHHHHHHHHHHHHHH-HHHHHT---T------??--------------------------------HH-----HHHHHHHHHHS?B?THHHH-HHHHTT??HHHHHHHHHHHHHHHHHHHHHHH-HHH-H-------------?G---------------GGHHH---------HHHHHHHHHHHTHHHHHHHHHHH---HH--H-G---G-----------------------GGHH--H-HH-H----------HHHH----HHHHHHHHH-HHHHHH--------THHHH--HHHHHHHHHHHHHHHHHHHHH----HHHHHHT-T-----------------------------??H------------------------HHHHHHHHHHH?B?H-----HHHHHH--HHHHST-T?G---------GGGHHHHHHHHHHHHHHHHHHHHHHH 3ZUX|A PF13594.1_Amidohydro_5_seed 1248 259 !Q:6,6|9,16|19,20|23,32|37,48|50,56|60,73|75,81|83,83|85,88|90,90|94,94|98,99|102,106|108,151|153,154|161,165|170,171|173,197|205,205|218,218|240,242|244,257 Q:0,5|7,8|17,18|21,22|33,36|49,49|57,59|74,74|82,82|84,84|89,89|91,93|95,97|100,101|107,107|152,152|155,160|166,169|172,172|198,204|206,217|219,239|243,243|258,258 EEEETT-EE--------EE--EE----------EGGG?????------?T-------TSE--------------E-----?-T-T--?-E-EEE?EEE--EE-----E?---------------------------------------????S??HHHHHH-----HHTT??H-------------------------HHHHHTT?THHHHHHHHHHS?HHHHHHHHHHHHHHHHHHTEE---E--------------E 1FWI|C PF13596.1_PAS_10_seed 87 165 !Q:10,10|25,31|33,33|36,39|41,45|48,51|63,66|68,71|73,77|80,81|86,89|92,92|95,97|106,107|109,109|111,111|117,120|122,125|127,128|130,131|137,137|141,141|148,148|151,152|163,163 Q:0,9|11,24|32,32|34,35|40,40|46,47|52,62|67,67|72,72|78,79|82,85|90,91|93,94|98,105|108,108|110,110|112,116|121,121|126,126|129,129|132,136|138,140|142,147|149,150|153,162|164,164 HHHHHHHSSS-EEEEEETTSBEEEE??----?S?GG----G----?SS?-??GGGTTSBGGGS----S---?H-----HH--HHHH----HH-HH---HHHHTTSB--S-E-EEEEE----E----E--T--TTTEE-EEE-EEEEEE?TT??EEEEEEEEEE?G 2QKP|A PF13597.1_NRDD_seed 45 904 !Q:0,10|19,23|28,32|42,43|46,48|50,50|52,52|55,55|59,59|70,71|77,83|86,87|95,95|102,106|109,111|135,135|165,165|171,180|204,207|212,214|220,225|228,228|230,230|235,237|240,245|249,249|253,279|281,284|286,305|308,313|318,319|321,321|329,329|333,335|337,346|368,370|373,383|385,385|389,397|405,405|408,410|416,421|423,423|425,426|429,463|465,472|475,475|495,497|502,502|505,505|507,507|509,509|514,518|522,522|524,524|526,526|528,528|530,536|538,545|548,548|559,559|564,564|566,570|577,581|586,591|601,601|609,615|618,618|620,620|623,625|628,629|633,639|645,653|674,674|681,683|697,708|710,710|712,719|721,728|735,745|748,751|755,757|764,767|770,770|773,773|778,778|782,783|788,794|797,797|804,804|811,811|813,814|816,816|823,824|832,834|836,837|842,842|846,859|868,868|873,873|875,903 Q:11,18|24,27|33,41|44,45|49,49|51,51|53,54|56,58|60,69|72,76|84,85|88,94|96,101|107,108|112,134|136,164|166,170|181,203|208,211|215,219|226,227|229,229|231,234|238,239|246,248|250,252|280,280|285,285|306,307|314,317|320,320|322,328|330,332|336,336|347,367|371,372|384,384|386,388|398,404|406,407|411,415|422,422|424,424|427,428|464,464|473,474|476,494|498,501|503,504|506,506|508,508|510,513|519,521|523,523|525,525|527,527|529,529|537,537|546,547|549,558|560,563|565,565|571,576|582,585|592,600|602,608|616,617|619,619|621,622|626,627|630,632|640,644|654,673|675,680|684,696|709,709|711,711|720,720|729,734|746,747|752,754|758,763|768,769|771,772|774,777|779,781|784,787|795,796|798,803|805,810|812,812|815,815|817,822|825,831|835,835|838,841|843,845|860,867|869,872|874,874 ??????????-SSHHHHHH-----HHHH-----HHHHHHHHH--HS-?-H-H-HH-HHH-HHTSEEETTT--TTTTS?--????EE??HHHHHHS?EEETTE-----EE???SSHHHHHHHHHHHHHHHHTTSSS?EEETTHHHHHHHHHHHHHHHHHHHHHHTT?SSHHH----------HHHHHHHHHHHHHHHHHHHHHHH???-TTSS???EEEEE--????SH-H-HHHH---HH------HHH-HHH---------------------------H----H?-------------------BT------TTTB??S?SEEEEEE?TTT---T----------SSTTSTTHHHHHHHHHHHHHH???EE-----------E-EHH---------HHHHHHT?SS???BTTTB????-?B?T--TS?----------------------------------B??------TT?BEEEEEEEEHHHHHHTTEE---TTEE?HH-H-H-HHHH-----HHH-H-H-H-H-------H--------HH-HHHHHHHTTT?BGGG?H-----HHHTSS-----TTSS---???TTSBTHHHH-TTTTSEE-------EE-E-EE--?HH--HHH-------HHHTS-------??HHHHHHHHHHHHHHHHHHHS?EEEEEE???TTHHHHHHHHHHH------------H-H?-----??T--------TTTTTS---??----??TT??-?TTS???HHHHHH----HH-HH-HHTT?TTB??EEEE?-??-?-TT?HHHHHH-HHHHHH-H--H?SEEEEE??EEEETTT???S??ESEE?SSS????----------GGGEEEEB?SSSS?B?????------????????-????????? 1HK8|A PF13599.1_Pentapeptide_4_seed 86 139 !Q:0,0|10,10|12,21|24,25|27,27|30,35|45,45|47,48|51,51|53,53|56,56|63,72|76,76|78,83|86,86|88,88|91,91|93,93|95,97|101,104|109,109|111,111|113,113|115,115|117,118|121,132|135,135|137,138 Q:1,9|11,11|22,23|26,26|28,29|36,44|46,46|49,50|52,52|54,55|57,62|73,75|77,77|84,85|87,87|89,90|92,92|94,94|98,100|105,108|110,110|112,112|114,114|116,116|119,120|133,134|136,136 ?EEEEEEEES?B-?--------TT-?B?TT?-----EEEEEEEES?B-?TT?B?TT?EEEEEE----------EES?B-----?TT?B?TT?E-E---EEE----EEES?B?T-T?B?-TT--?------?-?TT?B-? 2O6W|A PF13601.1_HTH_34_seed 35 83 !Q:11,13|28,29|52,52|56,57|64,64 Q:0,10|14,27|30,51|53,55|58,63|65,82 HHHHHHHHHHH---HSEEEHHHHHHHTT??HHHHHHHHHHHHHTTSEEEEEE?SSS-?EEEEEE?HHHHHHHHHHHHHHHHHH 1UB9|A PF13602.1_ADH_zinc_N_2_seed 420 259 !Q:2,2|7,8|12,12|15,15|18,30|38,38|40,41|43,43|46,49|52,62|66,72|77,78|82,89|91,91|96,100|103,104|107,107|111,136|139,139|147,147|155,155|160,161|165,181|183,183|188,189|198,202|214,217|219,222|225,225|228,228|231,232|236,237|246,246|250,251|253,253 Q:0,1|3,6|9,11|13,14|16,17|31,37|39,39|42,42|44,45|50,51|63,65|73,76|79,81|90,90|92,95|101,102|105,106|108,110|137,138|140,146|148,154|156,159|162,164|182,182|184,187|190,197|203,213|218,218|223,224|226,227|229,230|233,235|238,245|247,249|252,252|254,258 HT?SEEE--ETT-TS?HH-------------HHHHHHH-S--S?EE----EE-----------EES-??----GGGH--HHH--------H-HTEE-----EE--EE-EEE??-----------------------?TT?SEEEEEE?HHHHHTT?EEEE??STT-----------------S?HHHH--HHHHHHHH-----HHTHHHHHHTS----S?-??EE-EE-EE--GGG--HHHHHHHH-HHT??S-SEEEE 3QWA|A PF13603.1_tRNA-synt_1_2_seed 115 238 !Q:4,4|14,14|18,19|21,23|25,32|35,35|40,40|43,44|49,50|65,67|71,71|85,85|95,99|102,102|110,110|114,116|118,123|132,134|140,140|146,146|150,150|162,169|171,175|178,178|181,192|196,200|202,208|210,210|214,217|222,224 Q:0,3|5,13|15,17|20,20|24,24|33,34|36,39|41,42|45,48|51,64|68,70|72,84|86,94|100,101|103,109|111,113|117,117|124,131|135,139|141,145|147,149|151,161|170,170|176,177|179,180|193,195|201,201|209,209|211,213|218,221|225,237 HHHH?EEEEEEEEE?BTT?-S---S-------?EE-EEES?GG--GGGG??EEEEETTSHHHHHH---HTT?HHHHHHHHHGGGS?SSHHHHHHS?--??EE-EEEEEEE?TTT-??E------EEEEEETT??-TTSSS-SEEEE?TTT?HHHHHHHHHTT--??????B?---?TT-SS--???--?----SSS??--?S-??---?B?SSG----GGTT??-HHHHHHHHHHHHH 2V0G|A PF13604.1_AAA_30_seed 84 280 !Q:1,2|15,15|17,18|25,25|29,29|37,37|45,57|59,59|61,63|77,77|82,93|96,102|104,104|118,121|125,127|132,153|155,155|157,161|166,167|171,172|184,184|186,187|189,190|197,197|201,203|207,209|219,223|228,231|235,239|242,242|246,246|256,268|277,278 Q:0,0|3,14|16,16|19,24|26,28|30,36|38,44|58,58|60,60|64,76|78,81|94,95|103,103|105,117|122,124|128,131|154,154|156,156|162,165|168,170|173,183|185,185|188,188|191,196|198,200|204,206|210,218|224,227|232,234|240,241|243,245|247,255|269,276|279,279 T??HHHHHHHHHHHH?S--EEEEEE?TTS?HHHHHHH-HHHHHHH-------------T-T-??EEEEESSHHHHHH-HHHH------------HT-------S?EEEHHHHTTEETT----EES?--SSSS--------------------??S?S-----EEEE??GGG??HHHHHHHHHTS?T--T?-EEEEEE?TTS???SSS-??HHHHHHHHS?----EEEE????HHH-----HS?HHH-HHHHHHTTT????------??-SSSEEEEE??S 1W36|D PF13606.1_Ank_3_seed 248 87 !Q:0,9|11,14|16,17|19,20|22,22|24,25|28,31|33,35|37,46|48,50|52,52|54,55|57,57|62,62|64,67|69,72|74,86 Q:10,10|15,15|18,18|21,21|23,23|26,27|32,32|36,36|47,47|51,51|53,53|56,56|58,61|63,63|68,68|73,73 ?--?--?--?H----H--H--H-H--HH----H---T----?-----H---H-H--H-HHHG-G----G----T--?---?---??? 1YMP|A PF13607.1_Succ_CoA_lig_seed 213 171 !Q:1,1|3,3|10,10|13,13|18,18|27,28|30,31|39,39|42,45|48,48|55,55|60,63|65,65|67,68|76,77|79,81|83,83|95,96|99,99|101,101|107,135|148,148|157,160|168,169 Q:0,0|2,2|4,9|11,12|14,17|19,26|29,29|32,38|40,41|46,47|49,54|56,59|64,64|66,66|69,75|78,78|82,82|84,94|97,98|100,100|102,106|136,147|149,156|161,167|170,170 E?S-EEEEES?HH-HHHH-HHHHHHHT--T-?EESEEEE?TT-??-SS?HHHHHH-HHTT---?S-S??EEEEEES??S?--H-HHHHHHHHHHH--HH-S?EEEEE???-----????????--????-??????HHHHHHHHHHTT?EEESSHHH----HHHHHTT--T 2FPP|A PF13609.1_Porin_4_seed 115 990 !Q:0,57|66,67|72,90|94,102|105,108|110,125|128,132|137,137|140,143|145,152|155,165|170,179|182,183|185,187|192,195|197,198|203,204|208,222|225,226|229,232|234,241|243,294|297,298|300,325|329,333|337,338|340,340|343,344|354,360|362,363|365,381|384,385|391,394|397,402|405,405|407,410|412,413|415,415|419,444|447,451|453,454|456,461|465,516|518,537|547,551|555,565|568,569|571,571|573,573|581,582|584,584|586,589|591,638|644,648|651,651|654,659|664,664|666,666|668,668|670,674|676,679|685,685|688,692|695,712|716,716|722,737|749,749|752,753|756,759|762,776|782,791|794,798|808,811|813,851|856,856|860,864|869,871|873,873|876,879|882,882|884,885|887,887|889,889|895,902|907,907|909,918|920,939|957,958|961,962|967,968|972,973|977,978|980,980|983,986|988,988 Q:58,65|68,71|91,93|103,104|109,109|126,127|133,136|138,139|144,144|153,154|166,169|180,181|184,184|188,191|196,196|199,202|205,207|223,224|227,228|233,233|242,242|295,296|299,299|326,328|334,336|339,339|341,342|345,353|361,361|364,364|382,383|386,390|395,396|403,404|406,406|411,411|414,414|416,418|445,446|452,452|455,455|462,464|517,517|538,546|552,554|566,567|570,570|572,572|574,580|583,583|585,585|590,590|639,643|649,650|652,653|660,663|665,665|667,667|669,669|675,675|680,684|686,687|693,694|713,715|717,721|738,748|750,751|754,755|760,761|777,781|792,793|799,807|812,812|852,855|857,859|865,868|872,872|874,875|880,881|883,883|886,886|888,888|890,894|903,906|908,908|919,919|940,956|959,960|963,966|969,971|974,976|979,979|981,982|987,987|989,989 -----------------------------?-??-------------------------EEEEEEEE--EEEE-------------------EES-------??TT----S--------------??EE-----EEEE?SS----S?----?--EE-----------EEEE----------EE--E---EETT----E--EEEE--EEE---------------EE??TT----T--------T----------------------------------------------------ST--T------??--?-------------??SEE-----EEE--E-EE--TTEEEEESS-------E--E?----------------HH--HHHHG----GG----?-TT-T----T?-S-SSS?-----------------------??SS----?T--T-?--??STT----------------------------------------------------T--------------------TSSEESSEE-----EEE?--??------BT--T-E-EEEEEEE??T-T?--?B------------------------------------------------TTBSS-----TT?EE------EEEE-E-E-E---?-S----SEEEE-EE-----EE------------------EEE-EEETT----------------EEEEEEEEEEE-EE--EE?---SS-?-------------EEEEE----------EE-----EEEEEETTS?---E---------------------------------------EEEE-EEE-----EEEE---E-EE----TT-T--E-E-EEEEE--------EEEE-E----------G--------------------GGTEEEEEEEEEEEEES--SS--SEEE--EEE--EEE--E-EE?---T-T 3A2S|X PF13614.1_AAA_31_seed 61 192 !Q:30,39|45,46|50,51|57,57|60,76|78,79|88,97|100,101|120,122|131,132|146,147|149,149|151,152|162,163|168,169|175,175|183,183 Q:0,29|40,44|47,49|52,56|58,59|77,77|80,87|98,99|102,119|123,130|133,145|148,148|150,150|153,161|164,167|170,174|176,182|184,191 EEEEEEESSTTSSHHHHHHHHHHHHTTSTT??--------EEEEE??TTT??GGGGT?SS??---------------S??HHHHHHTG----------GG??HHHHHHHSEEEETTEEEE???SSHHHHHH??HHHHHHHHHHHHH--H?S--EEEEEEESS??TTHH--HHGGG?SEEEEEE?SSHHHHHH 3FKQ|A PF13616.1_Rotamase_3_seed 68 174 !Q:3,6|11,17|31,33|45,68|81,81|85,85|95,97|101,101|107,112|118,123|126,131|134,134|145,146|151,151|154,154|166,168 Q:0,2|7,10|18,30|34,44|69,80|82,84|86,94|98,100|102,106|113,117|124,125|132,133|135,144|147,150|152,153|155,165|169,173 HTT????HHHH-------HHHHHHHGGGSEE??-EEEEEEEEESS------------------------HHHHHHHHHHHT-THH-HHHHHHHHH???TTT-GGGTT------EEEEE?-----SS------SS?HHHHHHHHHS-?TTEE?SS?EEETTEEEEEE---EEEEE 1ZK6|A PF13620.1_CarboxypepD_reg_seed 622 238 !Q:1,2|8,10|12,12|14,14|16,17|20,23|25,27|29,35|38,38|42,44|46,48|50,68|70,80|82,87|89,91|94,99|101,103|105,110|113,113|118,118|120,128|130,134|136,137|139,140|142,143|145,146|150,154|156,156|159,160|162,165|168,168|170,182|184,185|189,191|193,195|197,204|206,207|209,209|211,221|223,225|227,232|234,237 Q:0,0|3,7|11,11|13,13|15,15|18,19|24,24|28,28|36,37|39,41|45,45|49,49|69,69|81,81|88,88|92,93|100,100|104,104|111,112|114,117|119,119|129,129|135,135|138,138|141,141|144,144|147,149|155,155|157,158|161,161|166,167|169,169|183,183|186,188|192,192|196,196|205,205|208,208|210,210|222,222|226,226|233,233 E--EEEEE---E-E-T--TT-?--S---B?------TT?EEE---E---T-------------------T-----------E------E---EE------E---E-?--?-TT-SEEE-E--??---?-S-----E--E--E--E--EEE-----E?TT--B?--?EE-E-------------E--EEE-?-S---S--?-----E--E-E---?---?---E---E------E---? 4JDZ|B PF13621.1_Cupin_8_seed 90 1085 !Q:0,1|14,15|21,22|25,26|28,29|31,32|35,37|42,58|66,66|70,70|75,95|100,179|183,189|192,199|201,208|218,251|255,255|260,272|274,309|312,328|330,334|337,340|342,343|346,346|348,349|352,353|355,355|357,379|381,385|387,404|406,406|409,411|416,420|422,424|426,426|429,453|457,513|518,552|555,560|562,564|569,570|572,577|580,599|608,608|615,615|621,632|635,659|661,859|861,865|868,882|884,885|887,887|889,936|938,939|941,942|944,952|956,957|962,974|980,980|983,995|1000,1000|1003,1003|1008,1036|1039,1045|1047,1061|1063,1067|1075,1075|1078,1084 Q:2,13|16,20|23,24|27,27|30,30|33,34|38,41|59,65|67,69|71,74|96,99|180,182|190,191|200,200|209,217|252,254|256,259|273,273|310,311|329,329|335,336|341,341|344,345|347,347|350,351|354,354|356,356|380,380|386,386|405,405|407,408|412,415|421,421|425,425|427,428|454,456|514,517|553,554|561,561|565,568|571,571|578,579|600,607|609,614|616,620|633,634|660,660|860,860|866,867|883,883|886,886|888,888|937,937|940,940|943,943|953,955|958,961|975,979|981,982|996,999|1001,1002|1004,1007|1037,1038|1046,1046|1062,1062|1068,1074|1076,1077 ??HHHHHHHTTTTT??EEEES--SS--T--T--ST---HHHH--??-------------HHHHHHH-HTT-SEEE---------------------EEES?------------------------------------------------------------------------------?SSG-------GG------?-E--------EEEEEHHHH----------------------------------HHH-HTSS??------?----S---------------------------------??-BE-----------------E-----EE?---H--HH-H?-TT--G-G-----------------------G-----G-----------????---G-GG---GGSS-----S--?G-GG?------------------------EEE---------------------------------------------------------EEEE----------------------------------?TT--?---E---EEEE??S------SE--------------------EEEEEEES?EEEEEE?GGGGG------------GG------------------------?B-?----------------------------????--------------?----------??------------------------------------------------------------------------------------------------------------------------------------------B-----BS---------------S?-T-T------------------------------------------------S??T--T---------TSG--GGTT?---------??-EEEEE?TT?------------EEEE?TT?EEEE-----------------------------EE-------S---------------S-----SEEEEEE-EE????-?? 1MZE|A PF13622.1_4HBT_3_seed 200 637 !Q:0,1|6,33|38,38|41,41|45,47|59,72|74,96|109,112|115,115|120,124|131,139|141,141|152,153|156,162|166,186|188,189|199,246|249,249|251,264|268,269|271,271|273,276|279,280|283,284|288,314|322,323|325,358|361,362|366,366|375,375|377,415|418,421|423,431|438,438|440,443|452,493|500,504|508,523|525,546|548,549|555,555|560,572|578,582|584,584|592,593|602,619|622,622|624,625 Q:2,5|34,37|39,40|42,44|48,58|73,73|97,108|113,114|116,119|125,130|140,140|142,151|154,155|163,165|187,187|190,198|247,248|250,250|265,267|270,270|272,272|277,278|281,282|285,287|315,321|324,324|359,360|363,365|367,374|376,376|416,417|422,422|432,437|439,439|444,451|494,499|505,507|524,524|547,547|550,554|556,559|573,577|583,583|585,591|594,601|620,621|623,623|626,636 ??GGGB?---------------------------SSSB?HH-HHH---HHHHHHHHHST--------------T??---------------------SEEEEEEEEESS-???SS-EEEE-----EEEEEE---------E?SSEEEEEEEE--EE-------TTE---------------------E--EEEEEEEEE?????-----------------------------------------??EE?S??????-------?GGG--S?B??-?SS??GG--GGG---------------------------EEEEEEE??T----------------------------------TS??SSS?EEEEEEES-S??-??---------------------------------?HH----H---------HHHHTT?S--??HHHHHHTS?---------------------------------------??EEEEEE-----EEE----------------E?---------------------S-?HHHHH-HTTT?-----------?EEEEE-----E?SEEETTE--EEEEEEEE?-----------------TT-S-?EEEEEEEEEEE 3E1E|A PF13631.1_Cytochrom_B_N_2_seed 68 288 !Q:21,21|25,25|29,30|51,51|62,62|65,65|71,76|82,84|94,102|107,107|110,112|117,117|122,122|125,125|142,143|145,146|150,165|167,168|170,173|175,186|189,198|201,212|224,225|227,229|234,234|236,238|240,242|248,257|261,271|274,274|280,280|283,283 Q:0,20|22,24|26,28|31,50|52,61|63,64|66,70|77,81|85,93|103,106|108,109|113,116|118,121|123,124|126,141|144,144|147,149|166,166|169,169|174,174|187,188|199,200|213,223|226,226|230,233|235,235|239,239|243,247|258,260|272,273|275,279|281,282|284,287 HHHHHHHHHHHHHHHHTTGGG-SHH-HHH--HHHHHHHHHHHHHHHHHHTT?BHHHHHHHHH-HH-GGGGG------STTTH---HHHHHHHHT---------SSSS?HH---HHHH-HHHH-HH-HHHHHHHHHHHHHHHH--H--HTT????------------T--T---?S---??-------GG----------GE------------EEHHHHHHHHH--H---HHHH-H---H---HHHHH----------HHH-----------HH?TTSSS?GG-GGSB 1SQB|C PF13632.1_Glyco_trans_2_3_seed 101 603 !Q:4,5|10,10|12,16|24,27|30,30|32,32|35,35|38,39|41,46|48,53|57,67|69,72|74,79|81,87|90,91|93,93|98,99|101,107|110,111|115,115|126,126|131,145|152,152|157,158|160,160|162,177|181,194|196,201|203,210|214,214|224,225|227,227|231,237|239,242|245,288|290,290|293,300|302,324|328,328|332,341|343,343|347,348|353,367|372,372|377,377|381,381|384,385|393,433|436,437|441,450|452,452|454,454|456,460|464,465|467,469|471,473|476,478|480,480|482,497|501,503|505,512|515,519|522,522|524,561|563,565|567,569|574,574|576,587|589,593|599,600 Q:0,3|6,9|11,11|17,23|28,29|31,31|33,34|36,37|40,40|47,47|54,56|68,68|73,73|80,80|88,89|92,92|94,97|100,100|108,109|112,114|116,125|127,130|146,151|153,156|159,159|161,161|178,180|195,195|202,202|211,213|215,223|226,226|228,230|238,238|243,244|289,289|291,292|301,301|325,327|329,331|342,342|344,346|349,352|368,371|373,376|378,380|382,383|386,392|434,435|438,440|451,451|453,453|455,455|461,463|466,466|470,470|474,475|479,479|481,481|498,500|504,504|513,514|520,521|523,523|562,562|566,566|570,573|575,575|588,588|594,598|601,602 EEEE??TTEE-E----?TTHHHHH----HH-H-HH-HS--S------S-??---EEE---??--??--B----S------S-?--?--HH--H-HHHT??T-------TS??TTH-HHHHTHHHHH-HHTT-???-------??--SSSEEE-EHHH--H-H----------------HHT--------------T??---?S--------SSS-HHHHHHHHH--H-TTT-----??E----EE?-------------------------------??-?-------?E-EE?---???-S-----------------------HHH-HHH----------H-HHH--HHHH---------------HHHH-HHHS?TTS?SS??HHHHHHH-----------------------------------------HH--HHH----------H-T-T-----HHH--H---H---HH---H-H----------------HHH---H--------HH-----HH-H------?--?---?-?----------------------S???H---HHHH-H------------H-----HHHHH--HH 4HG6|A PF13633.1_N_methyl_3_seed 363 23 !Q:0,1|14,14 Q:2,13|15,22 ??HHHHHHHHHHHH-HHHHHHHH 2PIL|A PF13636.1_Nol1_Nop2_Fmu_2_seed 150 215 !Q:3,3|5,9|12,20|23,31|42,43|45,48|56,56|62,63|65,81|85,85|87,89|91,93|96,97|99,103|105,106|108,111|115,116|122,123|125,146|148,151|153,176|178,178|188,191|199,200|204,204|209,209|211,211 Q:0,2|4,4|10,11|21,22|32,41|44,44|49,55|57,61|64,64|82,84|86,86|90,90|94,95|98,98|104,104|107,107|112,114|117,121|124,124|147,147|152,152|177,177|179,187|192,198|201,203|205,208|210,210|212,214 EEE-E----?TT-?-?-?-?-TT?-------?EEEESEEEEE--E----ETTEEEE?HHHHH--T--------------???GGG-S?--E---EE--E----?H--H----HHH--HHHHT??E----------------------E?---S--?------------?-----?--E-EEEEEETTE----EEEEEEE--ETT-EEEE?S?GGG 3M6U|A PF13637.1_Ank_4_seed 86 119 !Q:0,2|4,5|12,18|21,23|27,29|32,32|36,40|42,43|45,46|48,59|62,71|74,85|90,90|93,95|99,108|110,110|117,117 Q:3,3|6,11|19,20|24,26|30,31|33,35|41,41|44,44|47,47|60,61|72,73|86,89|91,92|96,98|109,109|111,116|118,118 ???H--HHHHHH-------HT?--HHH---HH-HHH-----H--T--T--??--------TT??-----?--TT----??--?---HHHH-HH---HTT-----?----H-HHHHHH-H 1BI8|B PF13638.1_PIN_4_seed 147 364 !Q:3,3|9,10|19,20|25,50|55,56|73,81|85,93|95,98|105,106|108,122|125,125|127,130|132,134|140,147|152,180|183,183|185,192|195,199|201,201|203,225|228,229|232,235|237,238|241,280|284,285|294,297|302,322|328,329|333,335|345,345|348,349|352,361 Q:0,2|4,8|11,18|21,24|51,54|57,72|82,84|94,94|99,104|107,107|123,124|126,126|131,131|135,139|148,151|181,182|184,184|193,194|200,200|202,202|226,227|230,231|236,236|239,240|281,283|286,293|298,301|323,327|330,332|336,344|346,347|350,351|362,363 EEE?HHHHH--HHHHHHHH--HHHT--------------------------SSSE--EEEEHHHHHHHHHHHH?????????HHH---------H----HHHHHH--H---------------HH-H----H---HHHHH--------HHTT--------------------------?--TT-E--------EE-----E?T-----------------------TS-?EE----S??TT?????----------------???----------???--?HHH--HHHHHHHT????GGGG????-----------??????EEEEE--EEE???HHHHHHHHH-TT??EE--------?-HH 2HWX|A PF13639.1_zf-RING_2_seed 329 169 !Q:0,2|6,14|16,27|29,29|31,32|34,38|40,46|48,48|51,66|68,68|70,74|77,80|82,84|88,91|93,103|105,118|120,122|124,159|161,163|166,166|168,168 Q:3,5|15,15|28,28|30,30|33,33|39,39|47,47|49,50|67,67|69,69|75,76|81,81|85,87|92,92|104,104|119,119|123,123|160,160|164,165|167,167 ???TTT????----?T------------T-S??E-----E?------S-SS---------?----?-E-E?----TT----H---HHH----T-----------T--------------T---T------?-------?---------------------S?--SS-S? 3DPL|R PF13640.1_2OG-FeII_Oxy_3_seed 172 214 !Q:6,6|10,11|14,29|32,32|34,47|50,63|70,72|76,77|79,79|82,96|102,103|107,108|111,149|152,154|158,159|163,163|170,179|183,184|188,189|191,199|202,204 Q:0,5|7,9|12,13|30,31|33,33|48,49|64,69|73,75|78,78|80,81|97,101|104,106|109,110|150,151|155,157|160,162|164,169|180,182|185,187|190,190|200,201|205,213 EEEEEE?SSS??EE----------------EE?S?-------------SS?------------?SEEEEE---EEE-?B-TT??-------------HHHHB??EEE??TT--------------------------------?------SS--?EEE??BTT-EEEEEE?---------STT??EEE??B---------SS--?EEEEEEEEE 2G1M|A PF13641.1_Glyco_tranf_2_3_seed 37 501 !Q:0,3|8,10|14,14|17,21|26,28|32,33|37,38|41,43|45,46|49,50|54,55|63,64|66,72|75,78|80,80|82,82|84,87|93,94|96,99|107,108|110,110|112,113|116,116|120,129|131,132|142,142|148,149|151,175|177,182|188,188|194,195|199,199|209,215|219,225|227,228|232,232|236,237|240,242|244,245|247,249|252,257|261,262|264,264|267,275|286,286|289,290|292,299|301,301|307,307|309,310|312,312|323,336|338,338|340,349|353,353|362,363|367,380|382,389|391,402|407,408|412,413|422,424|427,428|431,432|434,435|437,441|443,443|447,461|465,472|477,478|482,485|489,489 Q:4,7|11,13|15,16|22,25|29,31|34,36|39,40|44,44|47,48|51,53|56,62|65,65|73,74|79,79|81,81|83,83|88,92|95,95|100,106|109,109|111,111|114,115|117,119|130,130|133,141|143,147|150,150|176,176|183,187|189,193|196,198|200,208|216,218|226,226|229,231|233,235|238,239|243,243|246,246|250,251|258,260|263,263|265,266|276,285|287,288|291,291|300,300|302,306|308,308|311,311|313,322|337,337|339,339|350,352|354,361|364,366|381,381|390,390|403,406|409,411|414,421|425,426|429,430|433,433|436,436|442,442|444,446|462,464|473,476|479,481|486,488|490,500 ??--EEEE??-BSS?HH-----HHHH---HHH--HHT--TS---H--HH--HTT--EEEEEEE--E?------SS----S?G-G----GSTTH--H----HHHHHHG--G-G--EE-EEE?---?---??H--HHHHHHHHH-HHHHH--H-----------?--?---------?S------EEEEE?SSEEE-?THH-HHHHHHHHH-------HBS-------S??EEE-EEE--EE---T--T---ST------TEE??S?EE---------EETTTTEEEE?TT??S?-------E-ETTTS?S--S?SSHHHHGGGB?-----?--?--?-S-B----?----?TTE-EEEEHHHH--HHH?-------------S------??S---?--------SSSS--HHH--HHHHHHHH---TT??EE--E--E-----E-EEE---------------EEE?------?SSSS??TTS----THH-HHHHHHHHHHH 3CKO|A PF13642.1_DUF4144_seed 25 118 !Q:5,6|9,12|28,33|36,37|43,43|49,49|51,70|80,81|98,100|106,106 Q:0,4|7,8|13,27|34,35|38,42|44,48|50,50|71,79|82,97|101,105|107,117 SSEEE??SS????EEESSHHHHHHHHTT??????TT??EEETT?EEEEE?T--------------------TSSEEEEEE??HHHHHHHHHHHHHHHT???SSSSS?SSHHHHHHHHH 2L6O|A PF13646.1_HEAT_2_seed 323 296 !Q:1,1|3,5|10,10|12,14|16,17|19,25|27,28|31,33|35,38|40,40|42,42|44,44|46,46|49,49|54,66|68,68|70,77|79,90|93,121|127,127|129,129|132,139|141,146|148,154|156,157|159,163|170,171|173,174|177,180|182,185|187,188|190,218|220,222|224,227|229,232|234,238|240,240|245,251|253,254|256,256|258,263|265,266|268,269|271,273|275,275|278,279|282,283|285,287|290,292|296,296 Q:0,0|2,2|6,9|11,11|15,15|18,18|26,26|29,30|34,34|39,39|41,41|43,43|45,45|47,48|50,53|67,67|69,69|78,78|91,92|122,126|128,128|130,131|140,140|147,147|155,155|158,158|164,169|172,172|175,176|181,181|186,186|189,189|219,219|223,223|228,228|233,233|239,239|241,244|252,252|255,255|257,257|264,264|267,267|270,270|274,274|276,277|280,281|284,284|288,289|293,295 H-H---HHHH-H---T--T------?S--SH---H----H-H-H-H-HH-HHHH-------------H-H--?--?--G------------GG-----------------------------HHHHH-H-HT--------T--?---S--?----H--H-----HHHHHH--H--HH----H----H--H------------?----------?-----G---G----G----H-----H-HHHH-------H--T-T?-----S--S--H---H-HH--HH--H---HH---HHH- 2JKT|B PF13649.1_Methyltransf_25_seed 78 299 !Q:5,5|8,12|14,14|17,17|20,23|28,56|58,74|79,81|85,85|90,115|118,119|122,141|147,152|155,165|167,167|169,174|177,181|183,183|185,190|193,227|229,232|239,256|262,270|272,272|274,274|288,288|291,292|294,294|297,297 Q:0,4|6,7|13,13|15,16|18,19|24,27|57,57|75,78|82,84|86,89|116,117|120,121|142,146|153,154|166,166|168,168|175,176|182,182|184,184|191,192|228,228|233,238|257,261|271,271|273,273|275,287|289,290|293,293|295,296|298,298 EEEET?TT?----H-HH-HH----HHHT-----------------------------T----------------?EEEE---EES?HHHH--------------------------HH--HH--------------------HHHHH------TT?--------??E-E------EE-----S?G------GG-----?--------?----------?--------?S---?EEEEEE-----------------?SSGGG---------G-S?HHHHHHHHHHHHH-HE--E-EE-E 1BHJ|A PF13650.1_Asp_protease_2_seed 300 277 !Q:1,3|8,11|13,13|15,20|22,23|25,27|29,31|36,36|39,41|43,43|45,48|52,55|58,59|62,65|67,67|69,69|71,75|77,81|84,85|87,88|91,91|93,95|98,104|107,132|134,134|136,136|138,139|141,141|143,145|147,147|149,149|152,154|156,165|168,169|171,172|174,174|176,185|187,188|191,191|194,201|203,209|211,211|214,214|217,229|231,241|243,245|247,254|256,262|265,271|273,273 Q:0,0|4,7|12,12|14,14|21,21|24,24|28,28|32,35|37,38|42,42|44,44|49,51|56,57|60,61|66,66|68,68|70,70|76,76|82,83|86,86|89,90|92,92|96,97|105,106|133,133|135,135|137,137|140,140|142,142|146,146|148,148|150,151|155,155|166,167|170,170|173,173|175,175|186,186|189,190|192,193|202,202|210,210|212,213|215,216|230,230|242,242|246,246|255,255|263,264|272,272|274,276 E---EEEE----T-T------E--E---E---EEEE?TT-?-S-S--?-EEE----HH--HH----H-H-T-----T-?---GG--G--EE-G---GG?------EE-?--?--?---?--?-?------?--E-E-E--E-E---E-E-EE---E----------EE--E--T-T----------E--EE-EE--------E-------E-EE-ET-------------T-----?-----S---S--------S-------EE-------E?HHH 1APT|E PF13652.1_DUF4146_seed 11 113 !Q:0,1|22,22|39,39|50,50|60,60|75,75|86,86|98,99|107,107|112,112 Q:2,21|23,38|40,49|51,59|61,74|76,85|87,97|100,106|108,111 ??HHHHHHHHHHHHHHHHHHTT?SEESSSSEEEEEEEEE-TTEEEEEEEE?HHHHHHHHH?HHHHHHHHHHHHHT?HHHHHHHTTT?EEEEEEEETTT??EEEEEEE?HHHH? 3NPD|A PF13653.1_GDPD_2_seed 73 75 !Q:5,19|21,34|37,45|48,56|61,61|65,65|72,72 Q:0,4|20,20|35,36|46,47|57,60|62,64|66,71|73,74 EEEEE-??-----------?S--------------HH---------HH---------HHHH-HHT?SEEEES?HH 3CH0|A PF13654.1_AAA_32_seed 125 711 !Q:2,13|15,15|19,19|28,29|33,33|35,35|38,38|44,45|49,49|61,65|68,75|81,82|93,93|107,319|322,360|364,408|410,410|412,412|414,414|417,421|423,446|450,452|456,456|459,460|466,466|469,481|483,488|493,494|511,511|517,517|528,532|534,565|568,574|581,581|591,591|605,606|611,612|628,628|630,634|644,645|648,649|652,653|656,657|659,660|663,663|667,668|671,672|689,692|696,696 Q:0,1|14,14|16,18|20,27|30,32|34,34|36,37|39,43|46,48|50,60|66,67|76,80|83,92|94,106|320,321|361,363|409,409|411,411|413,413|415,416|422,422|447,449|453,455|457,458|461,465|467,468|482,482|489,492|495,510|512,516|518,527|533,533|566,567|575,580|582,590|592,604|607,610|613,627|629,629|635,643|646,647|650,651|654,655|658,658|661,662|664,666|669,670|673,688|693,695|697,710 TS??-???-----?T-TTT?HHHHHHHH--HHH-H-HT?EEEEE??TTS?HHHHHHHHHTT??---BS----????EEEEE--SSSSEEEEEE?STTTTSTTHHHHH??????-?????????????????????????????????????????????-??????----??----??---?-----------?-?---------??----------------------------------?????????---------?????????-?????----???????----????????????----?----???----???TT---?------??????????????---------------SSS??????-----------------?-------------------??S?E-E-EE---??S?-----------------------BSS-??EEE?SS??HHHHH?EE???????-?????G------GGEE??HHHHTTTSEEEEEHHH-HHHTT?HHHHHHHHHH?????B?------???--------??---?------??EE???????EEEEEE?TTHHHHHHT-SHHHHHHEEEEEE??SEEE??HHHHHHHHHHHHHTT?E-----EBHHHHHHH--HH--HH--HH--H--TT?TTE--EE??HHHHHHHHHHHHHHTT----TEE?HHHHHHHHHHHHHH 3K1J|A PF13656.1_RNA_pol_L_2_seed 53 97 !Q:1,1|9,10|25,25|35,36|38,38|41,48|50,50|59,61|65,73|97,97 Q:0,0|2,8|11,24|26,34|37,37|39,40|49,49|51,58|62,64|74,96 S?EEEEEES??HHHHHHHHHHHHTS-TTEEEEEEE?-S?SS--------S?EEEEEEEE?--TTS--------?HHHHHHHHHHHHHHHHHHHHHHH- 1K83|K PF13657.1_Couple_hipA_seed 185 264 !Q:6,6|8,11|13,16|21,21|23,24|26,30|33,36|38,42|46,46|48,48|54,56|59,65|67,68|70,70|72,75|78,98|101,119|121,148|150,156|161,177|184,184|186,186|188,190|195,199|202,206|209,213|215,216|218,224|226,231|234,235|240,244|246,246|250,251|253,253|255,256 Q:0,5|7,7|12,12|17,20|22,22|25,25|31,32|37,37|43,45|47,47|49,53|57,58|66,66|69,69|71,71|76,77|99,100|120,120|149,149|157,160|178,183|185,185|187,187|191,194|200,201|207,208|214,214|217,217|225,225|232,233|236,239|245,245|247,249|252,252|254,254|257,263 EEEEET-T----E----EEEE?E--E-?---TT----S----?EEB?B?HHHHS--?TT--??--?S--B-T----TB------???------------SS-----------------?-B----------?------?----------H-------HHHH-----------------HHHTTS?S?H---HHHH-----HH-----HH-----H--H-----??S-----?SS--HHHH-----H-HHH?-S-S-?SSSEEEE 3FBR|A PF13659.1_Methyltransf_26_seed 167 661 !Q:1,8|14,14|19,19|21,21|23,24|29,29|33,80|82,87|90,90|95,95|98,99|102,171|176,178|181,206|211,215|219,234|236,239|241,349|351,354|358,360|362,363|365,365|368,420|422,426|428,431|433,456|462,465|467,509|511,516|519,519|521,526|528,602|606,620|623,623|625,626|630,630|633,633|636,636|639,640|642,642|648,651|653,660 Q:0,0|9,13|15,18|20,20|22,22|25,28|30,32|81,81|88,89|91,94|96,97|100,101|172,175|179,180|207,210|216,218|235,235|240,240|350,350|355,357|361,361|364,364|366,367|421,421|427,427|432,432|457,461|466,466|510,510|517,518|520,520|527,527|603,605|621,622|624,624|627,629|631,632|634,635|637,638|641,641|643,647|652,652 T?------?EEESS?TTSH-H-H--HHHH-HHH-----------------------------------------------?T------TS?EEEE-ES-?HH----------------------------------------------------------------------HHHH---HH--------------------------HHHH-----HTT------------?---T----T-----------------------------------------------------------------------------------------------------------?-E----EEE??-G--G-GG-----------------------------------------------------G-----G----T-?-----?-?-------------?SEEEE??-?S-------------------?---?-?------------????-H------HH-H------H---------------------------------------------------------------------------HHH---------------HH-H--HHH-HH-TS?TT-?E-EEEEE----S-------? 3OZS|A PF13660.1_DUF4147_seed 229 407 !Q:26,27|29,71|90,90|95,102|105,113|115,120|122,122|125,125|133,141|143,160|162,172|174,195|197,202|207,209|211,212|216,217|233,237|239,242|245,245|252,252|260,261|263,263|265,272|274,275|291,292|316,317|320,321|323,324|332,333|337,338|340,340|342,342|345,351|353,359|361,361|365,372|377,378|387,393|395,396|398,398|406,406 Q:0,25|28,28|72,89|91,94|103,104|114,114|121,121|123,124|126,132|142,142|161,161|173,173|196,196|203,206|210,210|213,215|218,232|238,238|243,244|246,251|253,259|262,262|264,264|273,273|276,290|293,315|318,319|322,322|325,331|334,336|339,339|341,341|343,344|352,352|360,360|362,364|373,376|379,386|394,394|397,397|399,405 HHHHHHHHHHHHTTSHHHHHHTTHHH--H-------------------------------------?---??SEEEEEESTTHHHHHHHH-HHHH--------GG---------G------E-EE-EEEEEET---------T?----?--?---------S?------?---T----------------------T--?---EEEE---E?-SSS??HHHHHHHHHHHHHHS-----S-?-?TT?EEEEEE?TTHHHHS??B?T--------T??HHHHHHHHHHHHHTT??HHHHHHHHHTTBSSTTTHHHHHH--TT--S--EEEEEEE??STT??T-T-TG-------G-------G?TTS???--?-?HHHH--HHHHHHTT?---???H--H-HHHHHTS? 2B8N|A PF13661.1_2OG-FeII_Oxy_4_seed 39 101 !Q:3,4|8,19|21,22|29,29|33,34|38,38|40,40|43,44|46,66|75,75|77,78|81,82|88,89|93,94|97,97|100,100 Q:0,2|5,7|20,20|23,28|30,32|35,37|39,39|41,42|45,45|67,74|76,76|79,80|83,87|90,92|95,96|98,99 SSS??EEE------------E??EEEEEE?SSS??EEE?S?SS??S---------------------EEEEEEEE?B--TT??HHHHB??EEE??TT?SS? 2G1M|A PF13662.1_Toprim_4_seed 195 149 !Q:19,23|29,36|38,40|42,45|52,52|59,59|70,90|96,98|102,110|119,122|126,135|142,142|147,148 Q:0,18|24,28|37,37|41,41|46,51|53,58|60,69|91,95|99,101|111,118|123,125|136,141|143,146 EEEEEESSHHHHHHHHTTS--???EEEEE-------?S---S??--BTTTTB?GGGTTH-HHHHHHHHHS?-------------------?SEEEE???SSH---------HHHHHHHH----HHH----------HHTTTT?EEEE?? 3VDP|A PF13667.1_ThiC-associated_seed 217 106 !Q:1,2|5,5|10,10|13,13|15,15|20,20|28,30|33,55|57,65|70,72|77,77|81,83|87,87|89,91|102,102 Q:0,0|3,4|6,9|11,12|14,14|16,19|21,27|31,32|56,56|66,69|73,76|78,80|84,86|88,88|92,101|103,105 S??TT?EEEE-EE?S-SSTT?EEEEEEE???GG-----------------------G?-----???EEEE???GGGG?TTS???TTT?S?-?TTHHHHHHTS?EEE 3EPN|A PF13669.1_Glyoxalase_4_seed 77 339 !Q:6,6|8,11|20,22|28,58|61,63|68,69|71,80|82,82|84,84|86,93|95,96|98,172|174,181|183,184|186,194|196,201|203,203|205,205|208,208|210,213|215,216|220,221|225,225|227,231|233,233|235,239|242,247|254,256|260,260|263,263|266,267|270,270|274,279|281,287|298,298|300,301|303,306|309,311|314,314|316,317|321,322|324,330|332,333|335,335 Q:0,5|7,7|12,19|23,27|59,60|64,67|70,70|81,81|83,83|85,85|94,94|97,97|173,173|182,182|185,185|195,195|202,202|204,204|206,207|209,209|214,214|217,219|222,224|226,226|232,232|234,234|240,241|248,253|257,259|261,262|264,265|268,269|271,273|280,280|288,297|299,299|302,302|307,308|312,313|315,315|318,320|323,323|331,331|334,334|336,338 EEEEEE?S---?HHHHHHHH---HHHTT------------?--------?-----????EE???HHHH??E----------E-T-T--------E--E-------------?--------------?--------------?----------------?--------------E--------E--E---------E------E-E-EE-T----T--EEE--EEE-E-----E?S-----SS-----?HHHHHH---HHH?SE-EE--EE-EEE--?---S---?---HHHHHHHHHH-T--T??--EE---EE-E--EET--T-------E--E-EEE 1FA7|A PF13671.1_AAA_33_seed 146 343 !Q:5,6|15,18|22,22|24,27|32,35|37,45|48,48|50,50|53,53|55,86|90,147|149,149|151,169|180,180|184,189|191,191|194,201|203,214|216,220|222,222|226,229|231,231|237,238|241,242|246,259|261,261|264,264|268,270|272,272|279,292|300,308|310,311|313,313|315,325|336,342 Q:0,4|7,14|19,21|23,23|28,31|36,36|46,47|49,49|51,52|54,54|87,89|148,148|150,150|170,179|181,183|190,190|192,193|202,202|215,215|221,221|223,225|230,230|232,236|239,240|243,245|260,260|262,263|265,267|271,271|273,278|293,299|309,309|312,312|314,314|326,335 EEEEE??TTSSHHHH----HHH-H----TGGG----T--------?EE-E?HH-H--------------------------------HSS----------------------------------------------------------H-H-------------------HHHHHHHHHH-HTT---??-E-EE------?-S?---------??S-----H-HHH----H-HHHHH--HH--HHT??------------E-EE-EEE???H-HHHHHH--------------HHHHHHH-?-------T--T-S?-?------??HHHHHHHHHH?--??-? 3ZVN|A PF13672.1_PP2C_2_seed 68 504 !Q:0,1|3,4|6,7|10,15|20,26|28,28|30,30|33,37|39,41|43,44|46,47|53,53|55,60|62,63|65,66|72,75|82,82|85,89|91,91|99,117|122,133|135,135|138,138|144,146|150,151|160,193|198,198|201,204|207,212|214,214|217,217|223,226|228,228|231,235|237,240|242,242|244,250|253,254|261,261|264,265|269,278|280,281|283,283|285,285|288,290|292,304|306,311|317,348|350,353|358,358|360,370|372,373|376,376|379,393|400,405|408,411|417,417|422,431|433,433|436,443|445,453|458,458|461,462|464,466|468,468|470,476|480,490|495,497|502,502 Q:2,2|5,5|8,9|16,19|27,27|29,29|31,32|38,38|42,42|45,45|48,52|54,54|61,61|64,64|67,71|76,81|83,84|90,90|92,98|118,121|134,134|136,137|139,143|147,149|152,159|194,197|199,200|205,206|213,213|215,216|218,222|227,227|229,230|236,236|241,241|243,243|251,252|255,260|262,263|266,268|279,279|282,282|284,284|286,287|291,291|305,305|312,316|349,349|354,357|359,359|371,371|374,375|377,378|394,399|406,407|412,416|418,421|432,432|434,435|444,444|454,457|459,460|463,463|467,467|469,469|477,479|491,494|498,501|503,503 ??S--S-?SS----??EEEE-------E?T-TT?---?E---E--E--EEEEE?T------T--T--HHHHH----HHHHHH-HH-----H-HHHHHHH-------------------HHHT------------T?HH-HHHHH---HHH--HHHHHHHH----------------------------------HHHH?GG----GT------T?EE?EEEEE----E?TT-----S----S-E-------EE--EEEESS?EE--EEE---------?S--S?E-EE--?S?------?-?---B------TTTTT---??---------------???????----?S??-?SSTT?B-----------S??BS?TT????-----------EEEEEE---?-?TT---?EEEEE?HHHH----------T-TS-----?--H---------HHHH-HH--H---H?S------?HHH-----------HHHH---HHHH-H 3RT0|A PF13673.1_Acetyltransf_10_seed 46 209 !Q:11,11|16,16|18,20|22,22|26,26|34,35|37,37|47,51|58,64|66,66|76,80|83,87|89,90|93,97|99,99|101,106|108,110|112,115|117,119|123,129|133,137|139,140|143,143|147,147|158,158|163,163|166,167|170,171|174,174|176,177|183,189|191,191|195,197|201,201|205,205|208,208 Q:0,10|12,15|17,17|21,21|23,25|27,33|36,36|38,46|52,57|65,65|67,75|81,82|88,88|91,92|98,98|100,100|107,107|111,111|116,116|120,122|130,132|138,138|141,142|144,146|148,157|159,162|164,165|168,169|172,173|175,175|178,182|190,190|192,194|198,200|202,204|206,207 GHHHHHHHHHH-HHHH-H-?-T-TTS?HHHHHHH--H-GGGSSHHHH-----HHHHHT-------S-EEEEEEETT-----EE-----E--EE-----E-E------E---E----T---TTE-------EEE-----E--EE?GGG?SSSHHHHHHH-HHHH-HH--HT--TT?S--EEEEE-------E?TTT---HHH-HHT-TT? 2PR8|A PF13675.1_PilJ_seed 504 236 !Q:0,18|21,21|29,29|37,40|43,45|47,53|56,60|62,68|73,73|77,79|81,82|90,97|100,105|113,130|132,132|134,136|141,148|151,158|162,162|165,168|172,172|175,178|180,181|184,189|192,195|200,213|218,220|226,226|230,233 Q:19,20|22,28|30,36|41,42|46,46|54,55|61,61|69,72|74,76|80,80|83,89|98,99|106,112|131,131|133,133|137,140|149,150|159,161|163,164|169,171|173,174|179,179|182,183|190,191|196,199|214,217|221,225|227,229|234,235 ??-------??-------?HH-HHHHHHH-HHHHHHH----HH---H-------HT--?--S?-?----GGGH-HHH---H--HHHHHHT?-------HH------HHHHHHH------------------H-T-?-HHHH--------HH--------HHH-HH----HHT-HH----H--HH------HH---?SSGG--------------GTHH---HHHHH-HHH----HH 3EZH|A PF13676.1_TIR_2_seed 214 252 !Q:6,7|9,11|13,13|15,16|19,20|27,29|33,35|37,42|44,47|49,50|52,55|57,64|67,72|74,79|84,88|90,92|94,95|97,98|106,106|108,110|112,112|114,115|124,124|130,133|135,135|137,153|155,156|158,158|160,163|168,170|172,174|176,181|184,193|201,210|212,212|214,218|224,240|243,249 Q:0,5|8,8|12,12|14,14|17,18|21,26|30,32|36,36|43,43|48,48|51,51|56,56|65,66|73,73|80,83|89,89|93,93|96,96|99,105|107,107|111,111|113,113|116,123|125,129|134,134|136,136|154,154|157,157|159,159|164,167|171,171|175,175|182,183|194,200|211,211|213,213|219,223|241,242|250,251 EEEEEE--G---G-G--TT--TTHHHH---HHH---H------H----H--H----T?---?---EE---?--G------GGEE-?---T---T??H--HHHHHHH-H---T-S--EEEEEEEE-EHHHH----T-T------------?--??H--H-H----HHHH---T???T------TS------??-?EEEEEES-----??---T-G-----GGTTT---??----?-??----SS??-----EE 1FYX|A PF13682.1_CZB_seed 345 107 !Q:1,1|3,5|15,15|19,19|24,46|53,53|57,57|59,65|67,67|71,74|77,84|86,86 Q:0,0|2,2|6,14|16,18|20,23|47,52|54,56|58,58|66,66|68,70|75,76|85,85|87,106 H-H---HHHHHHHHH-HHH-HHHT----?????--???????????-HHHHHH-HTT?S-----??T-TTH----HH--------H-HHHHHHHHHHHHHHHHHHHH 3T9O|A PF13685.1_Fe-ADH_2_seed 57 458 !Q:5,5|17,19|21,24|26,31|41,43|48,50|64,67|70,70|72,74|77,79|83,95|97,102|109,111|117,125|127,130|132,140|144,144|162,163|166,167|174,175|191,192|199,200|202,205|219,219|236,238|240,240|242,244|246,253|257,258|261,261|267,270|273,278|281,288|290,290|292,300|307,307|309,311|314,315|317,323|325,332|334,334|336,346|351,355|362,365|367,372|374,374|377,379|384,389|391,392|401,401|412,417|421,428|430,433|435,451 Q:0,4|6,16|20,20|25,25|32,40|44,47|51,63|68,69|71,71|75,76|80,82|96,96|103,108|112,116|126,126|131,131|141,143|145,161|164,165|168,173|176,190|193,198|201,201|206,218|220,235|239,239|241,241|245,245|254,256|259,260|262,266|271,272|279,280|289,289|291,291|301,306|308,308|312,313|316,316|324,324|333,333|335,335|347,350|356,361|366,366|373,373|375,376|380,383|390,390|393,400|402,411|418,420|429,429|434,434|452,457 EEESS?GGGHHHHHGGG---T-?--S------EEEEEEETT---HHHH---HHHHHHHHHHTTT?---EE-E---EE---EEE--??----?----B------HHHHHH---HHTTS------?--T----T--??-----EEE-EEESHHHHHHHHHHHHH--HT??EEEEES??SSGGGTSSEEEEEET--TEEEEE--E????SEEEEEHHHHHTS?HHHHHHHHHHHHHHHH---H-H---H--------HHH--HH-HHTTS????HH------HH--------H-H---------HHHHHH-H---HH--H??---?-S-----?--T-T-----?-----HHHH-----HHHHHH----H------H-HH---HHHH------H--HHTSSTTT?SHHHHHHHHH------HHH-------?S----S?-------?-?------HHHHHH 1NVB|A PF13686.1_DrsE_2_seed 32 215 !Q:2,2|9,12|15,16|33,33|40,40|49,49|52,52|54,64|67,68|79,79|85,87|90,91|105,150|155,157|170,170|184,185|190,190|193,194|198,198|209,209 Q:0,1|3,8|13,14|17,32|34,39|41,48|50,51|53,53|65,66|69,78|80,84|88,89|92,104|151,154|158,169|171,183|186,189|191,192|195,197|199,208|210,214 TT?EEEEEE????HH--HHHHHHHHHHHHHHTT?EEEEEE?GGGGGGGB?GG-G???--------TT??HHHHHHHHHS?SSGGG???SS??GGGHHHHHHHHHH----------------------------------------------HHHT???HHHHHHHHHHTT?EEEEEHHHHHHHT??GGGB?TT?-EEE?HHHHHHHHHH?SEEEE 2QS7|A PF13688.1_Reprolysin_5_seed 48 383 !Q:2,2|8,8|12,12|20,20|23,24|26,40|54,57|60,60|67,68|71,79|83,88|90,93|98,100|105,106|108,108|110,112|115,126|132,132|135,135|141,142|144,161|180,180|188,191|194,196|198,201|205,208|213,213|219,233|235,243|245,248|252,254|258,260|262,267|272,272|279,280|285,287|301,309|312,326|329,329|332,349|354,357|360,360|363,366|368,372|379,382 Q:0,1|3,7|9,11|13,19|21,22|25,25|41,53|58,59|61,66|69,70|80,82|89,89|94,97|101,104|107,107|109,109|113,114|127,131|133,134|136,140|143,143|162,179|181,187|192,193|197,197|202,204|209,212|214,218|234,234|244,244|249,251|255,257|261,261|268,271|273,278|281,284|288,300|310,311|327,328|330,331|350,353|358,359|361,362|367,367|373,378 SS?EEEEE-EEE?HHHHHHT-ST--T?--------------HHHHHHHHHHHHH----HH-HHHHHT??TT---------SSS???--?E----EEEE---EEEE??S?B???TT???---------TTBSS?SS?TTSSS??H------------------HHHHHHHHHHHHHHHTTS-SEEEEEE????GG---G--??EEE????SSTT?SSSSS------------???E---------E---?TTT?--SEE???E------EEEE?EETTEE??HHHH---HHHHHHHHHHHTT???----??SS?--------------TT-TS??----------------GGGT-???TT?SS-???S----?STTTTS--?? 1BKC|A PF13690.1_CheX_seed 95 174 !Q:3,3|8,10|15,17|25,25|33,38|40,42|46,48|50,57|59,67|69,72|76,77|97,99|105,112|114,124|128,131|139,139|143,161|163,163|165,166 Q:0,2|4,7|11,14|18,24|26,32|39,39|43,45|49,49|58,58|68,68|73,75|78,96|100,104|113,113|125,127|132,138|140,142|162,162|164,164|167,173 EEE-EEEE---EESS--?EEEEEEE?HHHHHHH------H---HHH---H---?----S?----?---S?---HHH--HHHHHHHHHHHHHHHHHHH---HHHHT--------T?-----?----EEE-???EEEEEEE-EEE--???-------------?S-S?-EEEEEEE 3H4Y|A PF13691.1_Lactamase_B_4_seed 41 118 !Q:0,0|5,6|8,8|11,11|21,21|23,23|29,32|42,43|47,47|49,50|58,60|63,111 Q:1,4|7,7|9,10|12,20|22,22|24,28|33,41|44,46|48,48|51,57|61,62|112,117 ?BSSS??S-SS?SSEEEEEET-T-EEEEE-???TTHHHHHHH--SSS?G--GGEEEEE???SS-------------------------------------------------GGGTTT 3ZWF|A PF13692.1_Glyco_trans_1_4_seed 266 430 !Q:1,2|5,8|11,12|14,14|16,18|20,21|25,29|31,31|33,33|37,37|40,40|43,50|54,55|57,57|59,65|67,76|78,81|83,89|91,93|97,98|100,101|103,125|127,137|140,144|146,147|151,154|161,165|168,168|170,173|175,188|190,205|209,210|212,212|216,218|222,230|232,233|235,237|239,240|242,247|249,268|270,282|284,286|288,298|300,300|302,302|309,309|312,312|315,316|318,323|325,335|338,342|346,346|348,364|366,367|370,374|377,378|381,383|385,386|388,391|393,394|396,406|408,409|418,418|421,421|424,429 Q:0,0|3,4|9,10|13,13|15,15|19,19|22,24|30,30|32,32|34,36|38,39|41,42|51,53|56,56|58,58|66,66|77,77|82,82|90,90|94,96|99,99|102,102|126,126|138,139|145,145|148,150|155,160|166,167|169,169|174,174|189,189|206,208|211,211|213,215|219,221|231,231|234,234|238,238|241,241|248,248|269,269|283,283|287,287|299,299|301,301|303,308|310,311|313,314|317,317|324,324|336,337|343,345|347,347|365,365|368,369|375,376|379,380|384,384|387,387|392,392|395,395|407,407|410,417|419,420|422,423 E--EE----EE--S?T---T--SGG-----G?H-HHH-HH-HH--------HHH--H-H-------H-------?--T----T----?--E---EEE--E--S-?----------?----?-----H-----------HH-----H--HHH----TGGGGG-----GE-E----E----------?--?S---?-----------?HHH--H-HHH---HHT---?-----S--E---E--E------E---?--?-------?-----S??-----------S---S-----?-----H-H-HHHHHH-HT?EE--E------E-----???---HH-----HHH-H-----------------H--GG-----GT--SS---E--E-?-?T--T----?------H--HHHHHHHH-HH-HH-----? 2X6R|A PF13693.1_HTH_35_seed 22 79 !Q:1,2|15,16|26,27|39,39|53,53|62,62|65,78 Q:0,0|3,14|17,25|28,38|40,52|54,61|63,64 S??HHHHHHHHTTSS??HHHHHHHHS??HHHHHHTTTSS?HHHHHHHHHHTTS?HHHHSTTT?SS--??---------- 1NER|A PF13702.1_Lysozyme_like_seed 63 195 !Q:0,1|20,22|25,25|41,44|50,51|57,71|74,74|76,77|101,107|118,118|121,121|131,131|134,135|148,156|159,159|163,165|178,178|182,182|191,191|194,195 Q:2,19|23,24|26,40|45,49|52,56|72,73|75,75|78,100|108,117|119,120|122,130|132,133|136,147|157,158|160,162|166,177|179,181|183,190|192,193 ??HHHHTTHHHHHHHHHHTT--?GG-GHHHHHHHHHHHTTT---?SSSTT??TGGGT??-------------TT?S-?HHHHHHHHHHHHHHHHHHHHHHT?----?-HHHHHHHHHH?TH-HHHHHHTTT-SS??HHHHHHHHHHHT---------TT?EEE???TTTHHHHSSEEE-SSS?TTHHHHHH-TT?- 4FDY|A PF13709.1_DUF4159_seed 124 334 !Q:1,2|6,30|32,41|53,63|70,70|72,72|75,77|81,81|84,85|90,91|93,93|103,115|119,120|132,132|139,149|162,169|178,178|182,184|187,188|198,200|202,207|210,211|214,217|220,220|225,251|255,258|268,269|275,275|277,277|281,281|284,284|286,287|291,292|298,318 Q:0,0|3,5|31,31|42,52|64,69|71,71|73,74|78,80|82,83|86,89|92,92|94,102|116,118|121,131|133,138|150,161|170,177|179,181|185,186|189,197|201,201|208,209|212,213|218,219|221,224|252,254|259,267|270,274|276,276|278,280|282,283|285,285|288,290|293,297|319,333 B??EEE--???---------------?????S----------TTHHHHHHHHH-----------HHHSSS?B?SS?--EEE?TT?-TTGG--G?SEEEEEESS?????-------?HHH--HHHHHHHHHTT?EEEEEE?----------SSSSSSHHHHHH--------HHHHHHHS?TTS???EE??TTSGGGGSS---S??----SS??SS????SS?EEEE---------------------------ETT----EEEEEEETT-?HHHHH?B?TTS-SB?S??TTT--HHHHH---------------------HHHHHHHHHHHHHHH 4I66|A PF13710.1_ACT_5_seed 79 72 !Q:0,0|17,20|27,29|35,38|48,48|55,57 Q:1,16|21,26|30,34|39,47|49,54|58,71 ?STTHHHHHHHHHHHHT????EEEEEE--?SSTTE----EEEEEEEEE?HHHHHH---HHHHHHHSTTEEEE 2LVW|A PF13712.1_Glyco_tranf_2_5_seed 121 281 !Q:8,8|12,14|18,18|22,22|28,29|31,32|43,43|47,47|49,50|62,64|67,68|79,79|82,83|98,100|115,115|117,117|121,125|130,131|134,134|140,147|150,161|163,163|165,165|174,174|185,196|199,200|216,216|218,218|220,223|226,228|231,250|253,260|262,262|264,264|269,269|274,274|278,278 Q:0,7|9,11|15,17|19,21|23,27|30,30|33,42|44,46|48,48|51,61|65,66|69,78|80,81|84,97|101,114|116,116|118,120|126,129|132,133|135,139|148,149|162,162|164,164|166,173|175,184|197,198|201,215|217,217|219,219|224,225|229,230|251,252|261,261|263,263|265,268|270,273|275,277|279,280 EEEEEEES?HHH---HHH-HHH-HHHHT--T??TTTEEEEEEE?TTS?S??TTTHHHHHGGG-??SS--EEEEEETTEE?SS??HHHHHHHHHHHHHH?--TTEEEEESEEEESS?S?TTS??--?EEEE--EE-TTEEE--------EE------------E-S?SSEEEEEE?TTEEEEETTB?-----?--???SS??SSSSHHHHHHHHHHH-T-T?---EE---EE---?---?---?---?---?EE???-??-?S-H-HHHH-HHHH-HHH-HH 2NXV|A PF13714.1_PEP_mutase_seed 124 433 !Q:3,3|5,9|12,12|14,18|20,59|61,62|65,65|77,84|86,97|100,100|104,104|113,113|115,129|131,131|136,138|140,140|150,152|154,169|171,171|173,174|178,178|181,181|183,188|191,194|202,204|213,213|220,220|222,227|231,241|243,245|247,257|276,279|285,286|291,293|295,295|299,303|310,316|328,328|331,331|336,336|339,346|348,348|351,351|353,353|360,361|363,369|371,373|378,382|385,390|392,392|401,403|407,407|416,419|424,424|432,432 Q:0,2|4,4|10,11|13,13|19,19|60,60|63,64|66,76|85,85|98,99|101,103|105,112|114,114|130,130|132,135|139,139|141,149|153,153|170,170|172,172|175,177|179,180|182,182|189,190|195,201|205,212|214,219|221,221|228,230|242,242|246,246|258,275|280,284|287,290|294,294|296,298|304,309|317,327|329,330|332,335|337,338|347,347|349,350|352,352|354,359|362,362|370,370|374,377|383,384|391,391|393,400|404,406|408,415|420,423|425,431 HHH-T?---?TT-S----?E----------------------------------------E??EE?SHHHHHHHHHT--------T-----------?SS-EEE?HHHHHHHT-T????---------??S?HHHH---H-HHHHHHHHH-?-S----------------S?E--EEE?TT?S-----?SS----HHHHHHH---HHHHHHTT?SEEEEE?B-----?TTT?---------?B?-?H-----------HHHHHHHHHHHHHHHHTT??-?EEEEE??TTTT---S?GGG?----SHHHHH-------HHHHHHHHHHH-HT?SEEE?TT?-----??H-HH-H-HHHHHH?-S-------S?--EEEE?-?--SS-?----S?HHHHHHHT-??EEE?TTHHHHHH----HHHH-HHHHHHT? 4IQD|A PF13716.1_CRAL_TRIO_2_seed 101 436 !Q:3,3|9,10|14,14|21,21|25,34|38,41|43,72|85,85|88,90|95,97|104,104|107,108|110,139|142,144|152,197|202,202|205,230|235,235|242,242|245,251|260,288|300,301|304,366|370,387|394,398|403,407|411,416|418,427 Q:0,2|4,8|11,13|15,20|22,24|35,37|42,42|73,84|86,87|91,94|98,103|105,106|109,109|140,141|145,151|198,201|203,204|231,234|236,241|243,244|252,259|289,299|302,303|367,369|388,393|399,402|408,410|417,417|428,435 TSE-EEEEE-?TTS?EEEEEE-GGG?------?--BTT----B-----------------------------?HHHHHHHHHHHH-TT---TTTS?--EEEEEE?TT??G------------------------------GG???HHHHHHT----------------------------------------------TTSS?HH--------------------------HHHT-EEEEEE-ES??-----HHHHHHHH-----------------------------HTTTTTTTTTT-?SS---------------------------------------------------------------EEE-----------------?SSGGGG-----GGTS?----TTT?--???H----------HHHHTTSS 3HY5|A PF13718.1_GNAT_acetyltr_2_seed 88 311 !Q:13,13|23,23|33,76|79,90|103,106|109,111|114,114|122,124|127,127|139,139|156,156|160,160|162,170|181,182|187,255|257,257|266,267|277,277|280,280|286,286|289,290|294,296|304,309 Q:0,12|14,22|24,32|77,78|91,102|107,108|112,113|115,121|125,126|128,138|140,155|157,159|161,161|171,180|183,186|256,256|258,265|268,276|278,279|281,285|287,288|291,293|297,303|310,310 HHHHHHHHHSSSB?HHHHHHHHH?TTEEEEEEE------------------------------------------?-SS------------SEEEEEEEEEEE???-HH---HH-HHHHHTS???SS?HHHHHHHHHSS?TTGGGSEEEEEEEEEE?TTS?S---------SSHHHHHHHH--HHHT--?---------------------------------------------------------------?--S?SEEEEEEE??HHHHHHHHH-TT?EEEEE?SS??TTT???EEEEEEE-----?S 2ZPA|A PF13720.1_Acetyltransf_11_seed 349 128 !Q:2,2|10,10|12,12|16,17|22,22|27,27|32,33|35,36|38,39|43,43|55,55|57,65|71,71|75,75|78,81|85,90|92,92|96,96|101,103|107,109|111,112|114,122|124,124|126,127 Q:0,1|3,9|11,11|13,15|18,21|23,26|28,31|34,34|37,37|40,42|44,54|56,56|66,70|72,74|76,77|82,84|91,91|93,95|97,100|104,106|110,110|113,113|123,123|125,125 BB?TTEEEEE-B-TEE--EEEE?HHHH-HHTT??H--H--HHH-HHHHHHHHHHT-S?-?-----?HHHHH-HHH-HH----HHT------T?GGG-HHHH---HHH---H--H??-------S?B?? 2QIV|X PF13725.1_tRNA_bind_2_seed 114 239 !Q:5,9|11,11|16,16|21,24|26,51|53,133|141,144|149,149|152,155|160,162|166,168|176,198|200,205|215,217|227,227|231,233|236,237 Q:0,4|10,10|12,15|17,20|25,25|52,52|134,140|145,148|150,151|156,159|163,165|169,175|199,199|206,214|218,226|228,230|234,235|238,238 HHHHH-----H-HHHH-HHTS?--?S--------------------------S---??------------------------------???????---------------------------------------HHHHHHH----HHHH-HS??-?TTTT---HHH---HHHHHHH?---------------------?S----??HHHHHHHHS???HHHHHHHTT?SSH---HH--H 2ZPA|A PF13733.1_Glyco_transf_7N_seed 4 141 !Q:0,1|4,4|7,9|11,15|18,20|28,28|31,31|38,39|44,44|46,51|62,62|82,82|92,92|96,98|115,117|123,123|134,134|137,138 Q:2,3|5,6|10,10|16,17|21,27|29,30|32,37|40,43|45,45|52,61|63,81|83,91|93,95|99,114|118,122|124,133|135,136|139,140 ??SS?TT???B?????SS???HHHHHHH?TT?BTTTEE??SSSB?S?-----EEEEEEEESS?HHHHHHHHHHHHHHHHHTT?EEEEEEEEE?SSS???HHHHHHHHHHHHTTTS???EEEEE?TTEEESBTTS?SS??SS 1O0R|A PF13734.1_Inhibitor_I69_seed 3 198 !Q:0,83|85,89|93,103|111,117|124,124|128,128|138,141|143,143|158,160|165,197 Q:84,84|90,92|104,110|118,123|125,127|129,137|142,142|144,157|161,164 ------------------------------------------?????????????????????????????????????----?B????-TTS?----------SSSEEEE??-????EEEEES?TTS?SEEEEESSS????T?HHHHHHHHHHHHHH---HHGG???-----------------------??????? 1DKI|A PF13735.1_tRNA_NucTran2_2_seed 46 209 !Q:0,3|18,22|24,24|34,35|52,59|64,65|68,71|74,78|82,82|85,87|93,94|98,101|105,107|110,110|112,122|128,135|143,144|149,149|151,157|162,162|165,165|174,176|198,198 Q:4,17|23,23|25,33|36,51|60,63|66,67|72,73|79,81|83,84|88,92|95,97|102,104|108,109|111,111|123,127|136,142|145,148|150,150|158,161|163,164|166,173|177,197|199,208 --??SHHHHHHHHHHHHT-?---S?HHHHHHHTT??HHHHHHHHHHHHHHHH??------SGGG??HH----HH-----HHH?HH---HHHHH--HHH----HHH---HH-S?---------?SHHHH--------HHHHHHH--TTSS?S-------SSTT?SS?HHHHHHHH???SSHHHHHHHHHHHHHHTTTSS?SSHHHHHHHH 1MIY|A PF13738.1_Pyr_redox_3_seed 38 460 !Q:3,4|13,13|17,20|24,25|27,42|47,51|54,54|56,58|63,65|68,70|72,73|75,75|78,88|90,92|95,112|117,129|132,132|134,134|138,140|142,144|147,148|151,155|158,162|167,167|169,170|172,172|174,184|194,197|199,201|203,209|212,214|216,217|220,220|223,225|227,230|232,248|250,251|254,256|259,260|264,265|268,289|292,294|301,306|311,312|314,319|321,346|348,351|353,354|356,358|362,365|367,369|371,371|373,374|376,386|388,392|394,396|398,402|409,410|412,414|428,432|434,443|445,447|452,459 Q:0,2|5,12|14,16|21,23|26,26|43,46|52,53|55,55|59,62|66,67|71,71|74,74|76,77|89,89|93,94|113,116|130,131|133,133|135,137|141,141|145,146|149,150|156,157|163,166|168,168|171,171|173,173|185,193|198,198|202,202|210,211|215,215|218,219|221,222|226,226|231,231|249,249|252,253|257,258|261,263|266,267|290,291|295,300|307,310|313,313|320,320|347,347|352,352|355,355|359,361|366,366|370,370|372,372|375,375|387,387|393,393|397,397|403,408|411,411|415,427|433,433|444,444|448,451 EEE??SHHHHHHH-HHH----HHT--T?------?-?------EEEE?----SS-S---TTHH---HH---T--S?TT----------?B?--SS-----?-??-??------GGGT---??-------?TT?S-STT??-H---HH--HH?---?SS----?BHHH-H--H-H-----------HHHHHHHHT----T?--E-------EE--?S??EE-EE---E----E?----------------S--SS---EE--EEE--SS--?------------------?EE---EEEEEE???---STTS--B--??-?S--------------------------S----S?-E---EGG----G?--S?G--G-----------G-----S--?S-----SEEEEE??S---HHHHHHHHHHHHT-----T---?------E---EEEE?-?????? 2WHD|A PF13739.1_DUF4163_seed 48 179 !Q:8,10|13,17|22,23|25,25|33,33|35,36|38,39|51,52|60,73|77,85|87,90|92,95|98,98|102,106|109,115|119,128|130,132|138,142|150,154|163,163|170,170|175,175 Q:0,7|11,12|18,21|24,24|26,32|34,34|37,37|40,50|53,59|74,76|86,86|91,91|96,97|99,101|107,108|116,118|129,129|133,137|143,149|155,162|164,169|171,174|176,178 SEEEEEEE---EE--?--SSEE--E-EEEEEEE?S-?S-?HHHHHHHHHHH--HHHHHHH--------------HHH---------H----H----HH-HHH-----HH-------HTT??---?----S?--EEEEE-----EEEEEEE----?SSEEEEEE-EEEEES-SSSS?EEE 3CYG|A PF13740.1_ACT_6_seed 82 93 !Q:10,11|27,27|50,59|62,63|66,67|83,87 Q:0,9|12,26|28,49|60,61|64,65|68,82|88,92 EEEEEEEEEE??TTHHHHHHHHHHHTT?EEEEEEEEEETTEEEEEEEEEE?---------HH--HH--HHHHHHHHHHHHHHT?----EEEEE 3P96|A PF13743.1_Thioredoxin_5_seed 36 208 !Q:1,1|4,4|7,7|24,28|30,30|40,41|44,44|46,48|50,51|53,56|74,78|83,83|87,88|90,92|107,107|109,110|125,127|130,130|142,142|144,145|174,175|185,198|206,207 Q:0,0|2,3|5,6|8,23|29,29|31,39|42,43|45,45|49,49|52,52|57,73|79,82|84,86|89,89|93,106|108,108|111,124|128,129|131,141|143,143|146,173|176,184|199,205 E-EE?TT?HHHHHHHHHHHHHHHH-----S?TTSEEEEEE??SS?S???B??H----HHHHHHHHHHHHHHHHH?????TTHH-HHS??B???HHHHHHHHHHHTTT?H--HHHHHHHHHHHHTS???TT?HHHHHHHHHHT-T??HHHHHHHHTSHHHHHHHHHHHHHHHHTT??SSSEEEEEE--------------TTEEEEE?? 2IN3|A PF13744.1_HTH_37_seed 55 89 !Q:0,7|14,18|27,30|40,41|51,52|63,64|67,68 Q:8,13|19,26|31,39|42,50|53,62|65,66|69,88 ????????HHHHHH-----HHHHHHHH----HHHHHHHTT??HHHHHHHHT??HHHHHHHHTT??TT??HHHHHHHHHHTTEEEEEEEE 3DNV|B PF13745.1_HxxPF_rpt_seed 1348 215 !Q:2,3|5,5|11,14|17,17|19,32|35,37|39,43|46,46|53,54|56,83|85,107|110,116|118,119|121,121|124,126|128,131|133,134|136,138|140,143|145,147|149,152|154,154|159,162|167,167|170,174|176,181|183,194|206,207 Q:0,1|4,4|6,10|15,16|18,18|33,34|38,38|44,45|47,52|55,55|84,84|108,109|117,117|120,120|122,123|127,127|132,132|135,135|139,139|144,144|148,148|153,153|155,158|163,166|168,169|175,175|182,182|195,205|208,214 HT??S?HHHHH----HH-T--?-?-?----?-?TT---S-?---SS?SEEEEE--E------?--?-----?-------?----S---?---------?-?-?-----SS-------E--E-EE---E?---S--S?--S----S--?S----B?SSSE----EEEE-EE----?S------S-------?----EEEEEEEETTT??HHHHHHH 2JGP|A PF13746.1_Fer4_18_seed 40 206 !Q:5,5|10,29|31,31|36,37|39,41|49,68|70,70|73,73|75,99|102,134|139,142|147,174|178,181|186,187|189,192|198,198|201,203 Q:0,4|6,9|30,30|32,35|38,38|42,48|69,69|71,72|74,74|100,101|135,138|143,146|175,177|182,185|188,188|193,197|199,200|204,205 TTGGG?HHHH--------------------H?TTTS??H---HHHHHHH--------------------H-HH-T?------------------------TT?--------------------------??----HHHH----HHTT?---------------------------STT----TTTT??S--??HHHHH?TT???HH 3AE5|B PF13749.1_HATPase_c_4_seed 156 158 !Q:2,2|19,21|24,25|29,29|32,34|36,46|48,48|59,71|73,92|94,107|115,115|124,127|130,133|136,136|138,138|140,142|145,146|149,150|153,153 Q:0,1|3,18|22,23|26,28|30,31|35,35|47,47|49,58|72,72|93,93|108,114|116,123|128,129|134,135|137,137|139,139|143,144|147,148|151,152|154,157 SS?EEEETTTTEEEEEEES???TT??TTS-ST---T-?------???S?HHHHHHHHHT-------------T-------?------------S-------?------SSHHHHH-HHHHHHHH----TT????EE-E-E---ET--TT--EE-EEEE 3LMM|A PF13754.1_Big_3_4_seed 416 139 !Q:2,2|4,4|6,8|10,13|16,25|28,32|34,34|37,39|41,57|59,63|65,76|79,82|84,84|86,87|89,90|93,94|96,97|104,105|107,107|109,109|111,117|119,119|121,123|125,126|128,128|130,138 Q:0,1|3,3|5,5|9,9|14,15|26,27|33,33|35,36|40,40|58,58|64,64|77,78|83,83|85,85|88,88|91,92|95,95|98,103|106,106|108,108|110,110|118,118|120,120|124,124|127,127|129,129 TE-E-E---E--?-EE----?-----TT-----S?EE---E-----?-----?-----S-----S?--??-------SE----E-E--E--EE--E--EEEETT??E-E-E?--?-?-E-E---E--E-E--??????? 2YN5|A PF13759.1_2OG-FeII_Oxy_5_seed 92 164 !Q:7,8|11,12|17,24|27,30|39,42|44,45|47,66|72,72|75,82|87,88|91,91|93,99|102,110|114,116|121,124|126,129|131,131|141,141|146,150|153,154|156,156 Q:0,6|9,10|13,16|25,26|31,38|43,43|46,46|67,71|73,74|83,86|89,90|92,92|100,101|111,113|117,120|125,125|130,130|132,140|142,145|151,152|155,155|157,163 EEEEEEE?-TT??EEEE---??---TT?---SEEEEEES???-S--S?------------?------SEEEE?TT--------GGGG--SS-S-?-???-TT-----?-?-GGG--?SEEE----E???-T-TEEEEEETT?EEEE-????SS--S?EEEEEEE 3BVC|A PF13765.1_PRY_seed 191 63 !Q:0,1|3,3|7,8|14,14|18,19|24,28|31,43|47,49|52,53|55,55|60,61 Q:2,2|4,6|9,13|15,17|20,23|29,30|44,46|50,51|54,54|56,59|62,62 ??B?TTT??TTEEE?TTS?-EEEE----?SS?---?-???--??TTS-??SS--S?EEBS??B 2VOK|A PF13766.1_ECH_C_seed 180 212 !Q:2,3|16,25|27,28|40,48|50,55|57,60|62,66|76,76|80,82|96,99|102,103|105,117|135,148|150,157|168,187|190,191|196,200|203,204|211,211 Q:0,1|4,15|26,26|29,39|49,49|56,56|61,61|67,75|77,79|83,95|100,101|104,104|118,134|149,149|158,167|188,189|192,195|201,202|205,210 HH--HHTHHHHHHHTT-----?----S--SHHHHHHHHHH---------H----?-S----H-----HHHHHHHHH-TTS--?HHHHHHHHHHHHH----HT--T--------??-?-HHHHHHHHHHHHHHHTT----?---------H--------HHHHHHHHHH????--??---?-?-----?SS-?SGGG--??-HH--HHHGGG? 4HDT|A PF13771.1_zf-HC5HC2H_seed 144 159 !Q:0,43|47,48|51,58|60,64|67,68|72,72|74,74|78,79|91,93|96,101|104,107|109,117|121,123|126,141|144,144|153,154 Q:44,46|49,50|59,59|65,66|69,71|73,73|75,77|80,90|94,95|102,103|108,108|118,120|124,125|142,143|145,152|155,158 ???---------------------------??----????????BTT--TT--------B?---?SS-?EEE?S?TTT??EEEHHHHHHHT-??EE------EE----E---------EEE?--TT----------------TS?EEEEEEEE??GGGS 2LQ6|A PF13772.1_AIG2_2_seed 26 125 !Q:24,26|30,30|38,42|44,47|50,52|54,54|62,62|65,67|69,71|74,100|116,117 Q:0,23|27,29|31,37|43,43|48,49|53,53|55,61|63,64|68,68|72,73|101,115|118,124 EEEEEEEEEEGGGHHHHHHHTTGG---GTS?EEEEEEE-----E?---TT?-?E-EEEEEEE?SS---E---EE----??-------------------??HHHHHHHHHHHHHTT??HHHHHHH 2PN7|A PF13774.1_Longin_seed 180 157 !Q:3,3|9,12|14,17|20,25|32,32|36,36|44,46|48,53|56,72|82,82|85,86|104,115|119,128|130,130|135,138|144,150 Q:0,2|4,8|13,13|18,19|26,31|33,35|37,43|47,47|54,55|73,81|83,84|87,103|116,118|129,129|131,134|139,143|151,156 HHH-HHHTT??--T----TS---?--SEEEEE-ETT-EEEEEEE---E------TT-----------------EEEEEEEET-TS-?HHHHHHHHHHHHHHHHH------------HHT----------T-TTTT??--STTTT-------GGGHHH 3BW6|A PF13784.1_Fic_N_seed 115 95 !Q:21,21|23,24|30,31|48,51|61,62|64,64|66,73|75,75|95,95 Q:0,20|22,22|25,29|32,47|52,60|63,63|65,65|74,74|76,94 HHHHHHHHHHHHHHHHHHHHH?S-?HHHHH--HHHHHHHHHHHHHHTT????HHHHHHHSS??T-T--------S?HHHHHHHHHHHHHHHHHHH- 3EQX|A PF13793.1_Pribosyltran_N_seed 429 253 !Q:5,5|8,11|23,47|50,64|70,70|74,84|90,100|102,107|109,110|112,112|118,132|134,147|149,149|170,170|180,180|185,186|188,209|212,232|237,243 Q:0,4|6,7|12,22|48,49|65,69|71,73|85,89|101,101|108,108|111,111|113,117|133,133|148,148|150,169|171,179|181,184|187,187|210,211|233,236|244,252 EEEEE?SS?---HHHHHHHHHHH-------------------------TS-?-??--?-------EEEEE?TTS----------?EEEEE----------?S----??B--T?EEEEE???-?----------S--------------S-HHHHHHHHHHHHHHHHHTTB-SEEEEEESS?TTTT??S-------------------?-?TT-------????---------?HHHH-------HHHHHHHHT 1U9Z|A PF13794.1_MiaE_2_seed 3 185 !Q:31,31|63,64|83,85|114,114|126,127|145,145|175,176|181,184 Q:0,30|32,62|65,82|86,113|115,125|128,144|146,174|177,180 HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT?SSSTTHHHHHHHHHHHHHHHHHHHHHHHHTT??HHHHHGGGHHHHHHHHHT???SSHHHHHHHHHHHHHHHHHHHHHHTTTS?HHHHHHHHHHS??HHHHHHHHHHHHHHHHH?TTHHHHHHHHHHHHHHHHHHHHHHHHHHT??HHHH???? 3EZ0|A PF13801.1_Metal_resist_seed 97 145 !Q:0,30|32,43|52,54|70,70|72,74|84,84|98,99|101,102|135,135|137,139|145,145 Q:31,31|44,51|55,69|71,71|75,83|85,97|100,100|103,134|136,136|140,144 ???????????????????????????????T------------TTTTTTTS???HHHHHHHHHHHHHHH-H---HHHHHHHHH-HHHHHHHHHHHHH??S??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS?G---GGHHH- 3LAY|A PF13802.1_Gal_mutarotas_2_seed 218 140 !Q:1,2|9,17|19,20|23,27|29,33|35,50|55,70|73,77|79,85|87,93|102,111|114,115|117,123|125,125|131,132|135,136 Q:0,0|3,8|18,18|21,22|28,28|34,34|51,54|71,72|78,78|86,86|94,101|112,113|116,116|124,124|126,130|133,134|137,139 T??EEEEES-?-?-----S-?SS----?T-----T----------------EEEE?---???----??--?SS-----B-------S??-----SBEEEEEE----------ET--T-------S-EEEEE??SS??EEE 1XSJ|A PF13805.1_Pil1_seed 7 291 !Q:0,55|96,112|114,114|180,180|183,183|248,253|257,263|281,290 Q:56,95|113,113|115,179|181,182|184,247|254,256|264,280 ------------------------------------??????-?????????????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT-----------------S?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH?TT?THHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS??????SSS???????HHHHHHHHHHHHHHHHH???????--- 3PLT|A PF13806.1_Rieske_2_seed 77 146 !Q:11,11|15,18|23,23|25,26|35,39|41,41|43,43|45,45|47,53|58,60|76,76|78,78|86,86|90,91|98,99|103,123|125,126|128,129|131,133|138,138|146,146 Q:0,10|12,14|19,22|24,24|27,34|40,40|42,42|44,44|46,46|54,57|61,75|77,77|79,85|87,89|92,97|100,102|124,124|127,127|130,130|134,137|139,145 SEEEEEETTTS?TTB?--?EEEE-T--TEEEEEEB?----S-S-S-S-----??EEEB???TTTSSGGGTSSEEEE-S-SSSEEEE?SSS??EEETTT??BSS-------------------??S--S??B???EEES-SSEEEEE- 3GCE|A PF13812.1_PPR_3_seed 132 59 !Q:12,13|15,15|18,21|25,28|30,32|39,39|42,42|44,44|46,48|50,58 Q:0,11|14,14|16,17|22,24|29,29|33,38|40,41|43,43|45,45|49,49 HHHHHHHHHHHH--H-TT?---HHH----H---HHHHHH-HH-H-H---T------??? 4G25|A PF13816.1_Dehydratase_hem_seed 33 352 !Q:8,8|13,21|36,37|43,44|48,48|55,55|59,59|70,70|89,89|92,92|98,98|106,107|122,123|131,131|134,134|136,136|140,140|156,170|172,173|179,179|183,183|190,194|206,206|209,210|236,236|251,251|253,256|258,272|274,274|286,286|297,297|312,312|315,315|317,322|324,324|334,334|345,346 Q:0,7|9,12|22,35|38,42|45,47|49,54|56,58|60,69|71,88|90,91|93,97|99,105|108,121|124,130|132,133|135,135|137,139|141,155|171,171|174,178|180,182|184,189|195,205|207,208|211,235|237,250|252,252|257,257|273,273|275,285|287,296|298,311|313,314|316,316|323,323|325,333|335,344|347,351 EEEEEEEE?SGGG---------HHHHHHHHHHHHHH--TTSTT??SEE-EEEEEE?TTS?EEEEEEEEES?HHHHHHHHHSHHHHHHHH?GG-GGGSS?EEEEEEE??BGGGEEEEESSSSS??GGGGGSS-EE?S?BSS?SSTTHHHHHSGGGGT?????---------?S??EEEES?GGG?SEEEEE--??-TTEEEEEEEEE?TT??HHHHHHHHHHTHHHHHHHHHHHHHH?GGGTEEEEEEEEEE?T----T-??------------E-EEEEEEEEEES?HHHHHHHHHH?HHHHHHHHHHHHHT-TT?S------S?EEEEEEEEE?GGGEEEEEES??TTSGG 3A16|A PF13823.1_ADH_N_assoc_seed 120 23 !Q:0,0|17,20 Q:1,16|21,22 -EEEEEEETTEEEEEEE????SE 2DPH|A PF13831.1_PHD_2_seed 28 41 !Q:2,2|6,6|8,9|12,13|22,22|25,26|29,36 Q:0,1|3,5|7,7|10,11|14,21|23,24|27,28|37,40 SS?EEE?S--SS??EEEHHHHT?SS??SS----????HHHH 2KU3|A PF13833.1_EF-hand_8_seed 49 62 !Q:14,14|18,19|23,29|33,33|42,43|61,61 Q:0,13|15,17|20,22|30,32|34,41|44,60 SSSEEEHHHHHHHH-HHS--TTT-----??HHH-HHHHHHHH??BTTTEEEHHHHHHHHHH? 1MUX|A PF13837.1_Myb_DNA-bind_4_seed 185 210 !Q:0,0|4,4|13,13|17,19|22,25|29,30|35,46|49,50|61,64|66,72|74,76|78,82|84,88|90,106|109,111|128,137|139,139|141,144|146,161|163,202|205,209 Q:1,3|5,12|14,16|20,21|26,28|31,34|47,48|51,60|65,65|73,73|77,77|83,83|89,89|107,108|112,127|138,138|140,140|145,145|162,162|203,204 ?SSS?HHHHHHHH-HHH---HH----HHH--HHHH------------SS??HHHHHHHHHH----H-------H---H-----H-----T-----?---?----?-?HH---HHHHHHHHHHHHHHHS--??------S-S----S--??-?-----??---S----??--?-------------------------------TT?---- 2EBI|A PF13838.1_Clathrin_H_link_seed 51 70 !Q:1,1|4,4|20,20|37,37|47,48|51,53|55,55|58,60 Q:0,0|2,3|5,19|21,36|38,46|49,50|54,54|56,57|61,69 T?SS?HHHHHHHHHHHHHTT?HHHHHHHHHHSGGGSS?SHHHHHHHT--TS???T-TS??-HHHHHHHHH 1XI4|A PF13840.1_ACT_7_seed 192 81 !Q:12,12|14,19|21,21|24,27|37,43|48,51|55,56|58,58 Q:0,11|13,13|20,20|22,23|28,36|44,47|52,54|57,57|59,80 EEESSEEEEEEE?S------S?TT-???HHHHHHHHH-------HHTT????EEE--E?SSEEEEEEEGGGHHHHHHHHHH 1ZHV|A PF13841.1_Defensin_beta_2_seed 114 40 !Q:5,6|8,8|13,13|15,16|25,31|35,35|38,38 Q:0,4|7,7|9,12|14,14|17,24|32,34|36,37|39,39 HHHHT--T?EEES-S??TTEEEEEE----?--STT?EE-E 2LWL|A PF13844.1_Glyco_transf_41_seed 5 475 !Q:8,8|26,26|39,41|43,43|62,64|77,77|84,84|90,91|98,99|106,106|109,109|112,115|118,119|124,124|129,129|136,136|143,143|146,146|148,151|156,156|162,162|166,175|179,180|185,185|188,188|199,199|203,221|226,226|242,243|248,248|260,260|264,264|273,275|287,288|296,297|299,299|303,304|318,318|327,327|345,346|354,357|368,368|373,374|378,379|391,392|396,398|415,415|420,420|436,436|458,458 Q:0,7|9,25|27,38|42,42|44,61|65,76|78,83|85,89|92,97|100,105|107,108|110,111|116,117|120,123|125,128|130,135|137,142|144,145|147,147|152,155|157,161|163,165|176,178|181,184|186,187|189,198|200,202|222,225|227,241|244,247|249,259|261,263|265,272|276,286|289,295|298,298|300,302|305,317|319,326|328,344|347,353|358,367|369,372|375,377|380,390|393,395|399,414|416,419|421,435|437,457|459,474 EEEEEEES?SSSSHHHHHHTTHHHHS?TTTEEEEEEESS???S?HHHHHHHHHSSEEEEGGG???HHHHHHHHHHTT?SEEEES?SSBTT??THHHHT??SSEEEE?SS?SS????TT??EEEE?TTTS?GGGGGG?SSEEEE?SS?S????HHHH?GGGSS?EEE??????-???SSS--EEEE?TT-HHHHHHTSSS?EEE???????????????????EEEE?SSHHHHHHHHHHHHT??EEEE-TTEEEEEGGGH-HHH?HHHHHTSS???SEEEEEGGGTT??TTSEEEE??S?GGG??HHHHHHHHHHHHH?SSEEEEEE?TTGGGHHHHHHHHHHTT??GGGEEEE????HHHHHHHGGG?SEEE??SSS??SHHHHHHHHTT??EEB???SSGGGTHHHHHHHHHT?GGGB?SSHHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHSSTT?HHHHHHHHHHHHHHHH 4GZ3|A PF13847.1_Methyltransf_31_seed 66 282 !Q:0,1|3,4|9,13|16,16|28,31|34,34|36,37|39,39|41,44|50,51|61,64|73,75|81,83|85,85|89,95|97,104|106,106|110,117|122,139|141,141|143,149|152,152|161,174|191,210|221,221|225,225|230,238|249,250|256,258|261,262|271,276 Q:2,2|5,8|14,15|17,27|32,33|35,35|38,38|40,40|45,49|52,60|65,72|76,80|84,84|86,88|96,96|105,105|107,109|118,121|140,140|142,142|150,151|153,160|175,190|211,220|222,224|226,229|239,248|251,255|259,260|263,270|277,281 ??S??EEEE-----ET?TTTHHHHHHTT----TS?T--T?E----EEEEE??HHHHHHHHH----HHHSSSSE---EEEEE---S?TTT-??---?S--------S?EEE--------EEEE------------------S?G-------GG?SSHHHHHH--------------HHHHTEEEEEEEEEEE??------------------HHHHHTSEEE-TTS?HHHH-------??HHHHHHHHHH--HHHTT???TT--GGGTHHHH------HHHTT 1VQ1|A PF13848.1_Thioredoxin_6_seed 54 300 !Q:0,0|2,4|6,6|10,11|22,22|24,24|26,27|34,38|41,44|49,52|55,56|58,59|66,67|69,74|76,81|85,86|95,96|101,103|115,117|119,119|123,125|128,128|130,130|139,140|147,149|151,151|153,153|155,155|159,159|161,164|166,166|172,175|177,178|183,183|187,190|192,193|195,197|199,202|204,205|208,214|222,222|225,225|228,230|234,234|237,237|239,240|242,243|245,245|247,247|258,266|270,273|275,275|277,278|280,285|287,290 Q:1,1|5,5|7,9|12,21|23,23|25,25|28,33|39,40|45,48|53,54|57,57|60,65|68,68|75,75|82,84|87,94|97,100|104,114|118,118|120,122|126,127|129,129|131,138|141,146|150,150|152,152|154,154|156,158|160,160|165,165|167,171|176,176|179,182|184,186|191,191|194,194|198,198|203,203|206,207|215,221|223,224|226,227|231,233|235,236|238,238|241,241|244,244|246,246|248,257|267,269|274,274|276,276|279,279|286,286|291,299 ?S?--S?STH--HHHHHHHGGG?T-T--SEEEEE?---?HH----HHHH----TT??S--SEEEEE--E------T------TTT--EEEEEETH--HHHT?-?HHHHHHHHHHH???S-EEE??-TT-H-HHHHHTSS??EEEEEE---E?T-T-STT-H----H-HHHHH----H--HHHH-HHT----T--T---T---?E--EE-------EEETTSG-GG-HH---HHH-HT-T??G--G-G?SEEEEEESSS-?---?---EEE----E-T--T?-?-??H----HHHHHHHHH 3TRQ|A PF13854.1_Kelch_5_seed 78 104 !Q:0,0|3,7|10,11|14,14|16,20|22,22|24,28|30,42|45,50|54,56|58,59|62,67|69,69|73,73|77,84|87,89|92,94|99,102 Q:1,2|8,9|12,13|15,15|21,21|23,23|29,29|43,44|51,53|57,57|60,61|68,68|70,72|74,76|85,86|90,91|95,98|103,103 ?TT??--?BS-?EE-E-----E-E-----T-------------TE------EEE---E??EE------E?TTS?EEE--?--?-?EE---EE---ETTT----T 2UVK|A PF13855.1_LRR_8_seed 93 90 !Q:2,3|7,10|12,12|14,18|21,23|25,25|30,30|32,35|38,40|44,46|49,55|58,59|62,62|64,69|72,72|75,76|80,82|84,84|86,86|88,89 Q:0,1|4,6|11,11|13,13|19,20|24,24|26,29|31,31|36,37|41,43|47,48|56,57|60,61|63,63|70,71|73,74|77,79|83,83|85,85|87,87 TT??EEE??--S-S-???-EE--?T-TTST-T?---SS??-EEE??-SS??--?--EE--GG-G-?---?TT?TT??EEE??-S-S-S-? 2A0Z|A PF13856.1_Gifsy-2_seed 23 116 !Q:0,0|4,4|12,23|29,29|33,34|43,43|46,48|52,52|54,64|67,67|70,70|82,84|87,87|90,91|97,97|101,104|108,110|113,113 Q:1,3|5,11|24,28|30,32|35,42|44,45|49,51|53,53|65,66|68,69|71,81|85,86|88,89|92,96|98,100|105,107|111,112|114,115 ?SSS?SSSSSSS?????--?????EEEEE?TTT??EEEEEEEE?SS???SSS?S?---------?SS?SS?EEEESSSSTTT-??SS?EE--EETTT?EEB????SSS???TT?BB 1K0H|A PF13857.1_Ank_5_seed 81 66 !Q:5,8|11,13|16,21|29,29|32,32|41,44|48,49|52,54|57,60 Q:0,4|9,10|14,15|22,28|30,31|33,40|45,47|50,51|55,56|61,65 HHHHT--??TT???TT??---?HHHHHHH-HT?HHHHHHHH----HTT??TT???TT?-??HHHHH 1BI8|B PF13859.1_BNR_3_seed 201 957 !Q:7,7|21,22|24,49|51,53|55,58|60,99|102,104|106,109|111,112|116,126|129,132|136,136|138,141|143,158|160,164|168,168|170,170|172,224|226,228|231,236|238,257|259,260|263,263|271,273|276,277|283,295|297,301|304,306|308,308|310,319|321,322|324,327|329,343|346,346|350,354|356,378|381,381|383,385|388,408|411,422|427,429|433,438|440,443|445,446|449,454|457,459|464,490|493,493|495,501|505,505|508,513|519,520|522,547|549,554|556,567|571,571|573,576|579,579|582,582|584,587|590,591|596,607|610,621|624,633|636,636|638,641|643,654|658,660|664,664|666,667|670,672|674,674|677,679|681,681|684,684|686,700|712,715|717,719|721,721|733,739|750,750|753,760|766,774|777,777|779,779|781,794|799,804|806,811|816,829|833,836|840,844|852,869|872,877|880,881|883,883|889,894|896,897|901,901|908,908|910,912|915,919|921,924|928,928|935,950 Q:0,6|8,20|23,23|50,50|54,54|59,59|100,101|105,105|110,110|113,115|127,128|133,135|137,137|142,142|159,159|165,167|169,169|171,171|225,225|229,230|237,237|258,258|261,262|264,270|274,275|278,282|296,296|302,303|307,307|309,309|320,320|323,323|328,328|344,345|347,349|355,355|379,380|382,382|386,387|409,410|423,426|430,432|439,439|444,444|447,448|455,456|460,463|491,492|494,494|502,504|506,507|514,518|521,521|548,548|555,555|568,570|572,572|577,578|580,581|583,583|588,589|592,595|608,609|622,623|634,635|637,637|642,642|655,657|661,663|665,665|668,669|673,673|675,676|680,680|682,683|685,685|701,711|716,716|720,720|722,732|740,749|751,752|761,765|775,776|778,778|780,780|795,798|805,805|812,815|830,832|837,839|845,851|870,871|878,879|882,882|884,888|895,895|898,900|902,907|909,909|913,914|920,920|925,927|929,934|951,956 EEEEEEE-TTEEEEEEEEESS-?S-------------------------?S---S----S------------?---------------------------EE---E----E--EEE-----------ES----STT-S----S---------------?E-----EEE-E-E?-??---------?---------------------------------------S---ST------T----?---------------E--EE-EEEEEEE---TT--EEEEE-------------E-----EE---E-S----------S??S?---G---------------GG?SSS-----T-----------------------TE-E---EE---------------------EE------------EEEE---EEE?-----T----T--SS-----?EE---EEEE?------------------------??EE?G-------GGS?SE------ETTEE--E--------------------------E------E------------EEE?S----EE?EE?T----TS-?EEEE------------EE------------EE----------ET-T--??E------------EEE---EEE-E--SS---T-TS---S?EE?S????-----------TTEEEEEEEEE----T---T-EEEEEEEETTS----???EEEESSTTSS?EE-------?TTTTT---------TT-B?S--------------STTS-----?S??????EEEE--------------EET----TEE-----EEEEEEE----------??------SS?-----TT??B?EEEEE------E--SSS?EEEEEE?S?--TT--?--B-???EEE-EEETTE----------------EEEEEE 1MZ6|A PF13860.1_FlgD_ig_seed 102 143 !Q:0,0|4,4|7,13|17,28|35,36|40,40|45,46|52,52|54,54|57,57|60,61|67,69|73,73|75,76|84,85|88,88|92,113|115,116|120,120|126,135|138,138 Q:1,3|5,6|14,16|29,34|37,39|41,44|47,51|53,53|55,56|58,59|62,66|70,72|74,74|77,83|86,87|89,91|114,114|117,119|121,125|136,137|139,142 ?SEE-EE?------TTS?-----------EEEEEE--ESB?EEEE--EEEEE?T-TS?EE--EEEEE---EEE?S--EEEEEEE?-SB?TTS?---------------------B??SEE-EEEEE----------EE-EETT 3OSV|A PF13861.1_FLgD_tudor_seed 107 229 !Q:0,1|18,18|20,20|23,23|26,32|35,53|60,62|70,73|79,79|81,81|83,84|87,88|94,96|102,103|111,116|119,119|123,143|145,146|150,150|156,165|168,168|173,178|183,183|197,198|200,200|204,204|209,209|215,218|224,225|227,228 Q:2,17|19,19|21,22|24,25|33,34|54,59|63,69|74,78|80,80|82,82|85,86|89,93|97,101|104,110|117,118|120,122|144,144|147,149|151,155|166,167|169,172|179,182|184,196|199,199|201,203|205,208|210,214|219,223|226,226 -?HHHHTTTTTTSEEEEE?S-EE-EE?------SS??-----------------EEEEEE---ESSSEEE----EEEEE?S-S??EE--EEEEE---EESSS--EEEEEEE?-----SB?TTS?--------------------B??SEE-EEEEE----------EE-EETT----??EEEE?EEEEEEEEEEEEE--T-TEE-EEEE-TTTEE----EETTS??B?? 3OSV|A PF13866.1_zf-SAP30_seed 5 83 !Q:0,6|11,12|14,15|21,25|28,29|31,34|45,46|51,51|54,54|56,60|74,74|76,76|78,82 Q:7,10|13,13|16,20|26,27|30,30|35,44|47,50|52,53|55,55|61,73|75,75|77,77 -----??SSSB??E--EETTB--???SB??S????HHHHHHHHHH??SEEE?TT?S?????HHHHHHHHTTSSS?S?S??--- 2KDP|A PF13867.1_SAP30_Sin3_bdg_seed 36 64 !Q:1,1|6,11|17,17|21,24|26,27|29,30|32,32|46,50 Q:0,0|2,5|12,16|18,20|25,25|28,28|31,31|33,45|51,63 S?HHHH------HHHHH-HTT????S--S??H-HHHHHHHHHHHTT??-??HHHHHHHHHHHHH 2LD7|A PF13869.1_NUDIX_2_seed 25 253 !Q:0,0|5,5|8,8|17,20|22,26|28,31|49,49|51,51|66,66|74,78|82,91|94,94|99,100|103,104|106,106|120,134|136,141|143,144|146,169|181,181|186,187|191,192|195,195|198,198|209,210|221,221|234,234 Q:1,4|6,7|9,16|21,21|27,27|32,48|50,50|52,65|67,73|79,81|92,93|95,98|101,102|105,105|107,119|135,135|142,142|145,145|170,180|182,185|188,190|193,194|196,197|199,208|211,220|222,233|235,252 ?EEEE?BG-GGEEEEEE----S????-S?---SSHHHHHHHHHHHHHHH?S-EEEEEEEEEEESSS?EEEEEEE-?---SSS----?-----EE?SEEE??TT??H-HHHHHHHHHHHHB--------------?S------S--S?-------------------????EEEEEEEEEEE?SSSS??BSS??TT?SS?SEEEEEEEEE??SSEEEEEETT?EEEEEEHHHHTT?HHHHHHHHTTHHHHHTTS 3MDG|A PF13873.1_Myb_DNA-bind_5_seed 40 89 !Q:0,0|2,6|17,17|27,32|34,37|40,42|56,57|60,66|82,82|84,85|88,88 Q:1,1|7,16|18,26|33,33|38,39|43,55|58,59|67,81|83,83|86,87 ?S-????HHHHHHHHHH-HHHHHHHHH------H----SS??-HHHHHHHHHHHHH--HH?---???HHHHHHHHHHHHHHH?S-?SS? 2EBI|A PF13881.1_Rad60-SLD_2_seed 24 145 !Q:0,1|10,11|14,14|22,22|24,24|26,26|38,38|41,53|56,58|61,61|63,64|77,77|79,81|91,94|98,98|101,105|113,115|118,145 Q:2,9|12,13|15,21|23,23|25,25|27,37|39,40|54,55|59,60|62,62|65,76|78,78|82,90|95,97|99,100|106,112|116,117 ??EEEEEEET--TS?EEEEEEE?T-T?BHHHHHHHHHH-HS------------?TT--?SS-S??SGGGEEEEETTE-E??-TTSBGGGGS--??TTS?TT---??EEEEEEE???SS???????------??--?-????????- 2BWE|S PF13883.1_Pyrid_oxidase_2_seed 37 248 !Q:0,2|5,5|17,17|26,36|39,43|47,47|55,55|58,58|61,63|65,70|72,73|78,78|90,92|94,95|105,118|126,132|134,135|140,147|149,149|151,154|165,176|183,184|186,186|194,194|201,201|204,209|211,212|226,226|231,234|237,241 Q:3,4|6,16|18,25|37,38|44,46|48,54|56,57|59,60|64,64|71,71|74,77|79,89|93,93|96,104|119,125|133,133|136,139|148,148|150,150|155,164|177,182|185,185|187,193|195,200|202,203|210,210|213,225|227,230|235,236|242,247 ??-TT?HHHHHHHHHHH?SEEEEEEE--??------?GG-----GTT?EEEEEEE?BS?ST---T---???S??EEEE?TTSHHHHHHHH?-?E--EEEEEEGGG--------------TTHHHHH-------T??TTST--------T-S?---EEEEEEEEEE?----?------GGGHHH--H-HHHHHHH?GGGGGS?GG------G??EEEEEEEEEEEEE?SSSS---?EE?---?HHHHHH 3DNH|A PF13884.1_Peptidase_S74_seed 244 123 !Q:0,6|8,10|12,13|16,17|19,37|44,48|52,62|67,95|103,105|108,109|111,112 Q:7,7|11,11|14,15|18,18|38,43|49,51|63,66|96,102|106,107|110,110|113,122 ???????S?-?S??HH--H-------------------HHHHTT--???EEE-----??----HHHH-----------------------------HHHGGGS?-?EE--E??HHHHHHHHHH 3GW6|A PF13893.1_RRM_5_seed 106 98 !Q:1,1|9,9|11,13|15,16|19,19|23,24|28,33|35,36|43,45|47,49|51,51|62,63|66,67|69,69|73,75|77,79|82,83|85,86|88,88|93,95|97,97 Q:0,0|2,8|10,10|14,14|17,18|20,22|25,27|34,34|37,42|46,46|50,50|52,61|64,65|68,68|70,72|76,76|80,81|84,84|87,87|89,92|96,96 H-HHHHTTT-S-?-E--EE-EEE-?TTS------T--TEEEEE---E---S-SHHHHHHHHH--HH--T-TEE---E---TT--E--E-EEEE---E? 2ERR|A PF13894.1_zf-C2H2_4_seed 594 105 !Q:1,6|8,16|19,22|25,50|52,61|63,69|72,76|78,82|84,86|88,88|91,91|96,97|99,99|101,104 Q:0,0|7,7|17,18|23,24|51,51|62,62|70,71|77,77|83,83|87,87|89,90|92,95|98,98|100,100 E------E?-------?ST----TT------?-------------?-----E----------E-------SS-----H-----H---H-HH-HHHH--H-S---? 2PRT|A PF13895.1_Ig_2_seed 70 304 !Q:2,11|15,17|20,27|30,36|38,39|42,43|48,49|52,52|56,59|62,67|69,74|76,79|81,81|83,86|89,90|93,94|96,96|98,127|129,134|137,139|141,145|148,148|150,170|173,198|200,203|205,212|216,245|247,247|249,250|252,252|255,255|261,266|269,269|272,272|274,284|286,288|291,296|298,298|301,301 Q:0,1|12,14|18,19|28,29|37,37|40,41|44,47|50,51|53,55|60,61|68,68|75,75|80,80|82,82|87,88|91,92|95,95|97,97|128,128|135,136|140,140|146,147|149,149|171,172|199,199|204,204|213,215|246,246|248,248|251,251|253,254|256,260|267,268|270,271|273,273|285,285|289,290|297,297|299,300|302,303 SE----------EEE---ES?-------SE-------E--ET--TSEE--EE-EEE----EG------G------G??-?E-E----EE--EE--E-T------------------------------T------EE?-?S----?EE-E---------------------TT--------------------------E----E--------EEE-------------?------------?---S-S--S?EE-EEEEE------EE-TT-E-----------E---EE---???E-EE-EE 1DN2|A PF13899.1_Thioredoxin_7_seed 51 130 !Q:0,5|12,12|21,21|25,25|28,28|30,32|42,42|46,46|50,51|57,57|60,60|62,62|66,67|69,70|72,83|85,85|87,87|89,89|92,101|105,111|114,120|122,122 Q:6,11|13,20|22,24|26,27|29,29|33,41|43,45|47,49|52,56|58,59|61,61|63,65|68,68|71,71|84,84|86,86|88,88|90,91|102,104|112,113|121,121|123,129 ????--SHHHHH-HHHHTTTS?EEE-EE-B--?SSSHHHHHH-HHH-HTT?-HHHHH-HH-H-SSB??B??S------------S?S?T-TT---------?SST-------TS-------S?EEEEEBT 3VFI|A PF13905.1_Thioredoxin_8_seed 83 239 !Q:0,2|11,11|13,18|20,20|22,24|26,27|29,34|37,41|46,46|49,49|51,53|55,57|62,85|88,91|99,115|117,117|119,120|122,122|124,125|128,130|138,151|153,154|156,156|158,160|163,165|167,167|169,174|177,178|181,190|195,195|197,200|202,218|220,220|228,228|232,237 Q:3,10|12,12|19,19|21,21|25,25|28,28|35,36|42,45|47,48|50,50|54,54|58,61|86,87|92,98|116,116|118,118|121,121|123,123|126,127|131,137|152,152|155,155|157,157|161,162|166,166|168,168|175,176|179,180|191,194|196,196|201,201|219,219|221,227|229,231|238,238 ?--SEEEEEEE?T------T?H---H--H------HH-----HHHH-HH-H---H---HHHH?---------------?-------TT----EEEEEEE?------------?---S-S--H-H--HH---HHHHHHH----------??--S-?E-E??-TT?--H-H------HH--HH----------HHHT-T--??S-----------------S-SEEEEEE-TTS?-----E 4AJ8|A PF13909.1_zf-H2C2_5_seed 73 35 !Q:2,2|5,6|9,10|13,14|19,19|21,21|24,24|27,27|32,32 Q:0,1|3,4|7,8|11,12|15,18|20,20|22,23|25,26|28,31|33,34 EE?SS--SS-?EE--SSHH-H-HH-HH-HHHH-HS 2RSJ|A PF13912.1_zf-C2H2_6_seed 81 31 !Q:0,0|10,12|23,23|27,27|29,30 Q:1,9|13,22|24,26|28,28 ?SEETTTTEE?--SSHHHHHHHH-HHT-S?? 1FU9|A PF13920.1_zf-C3HC4_3_seed 585 122 !Q:4,8|11,17|20,20|22,27|29,35|37,51|53,53|57,58|60,63|65,70|74,74|81,103|106,106|109,110|112,114|116,119 Q:0,3|9,10|18,19|21,21|28,28|36,36|52,52|54,56|59,59|64,64|71,73|75,80|104,105|107,108|111,111|115,115|120,121 HHHB----?SS-------SS-S------S-------B--?---?--------E-EEE--T----T--?--?EEE?TTTGGG?----------------------SB?SS--S??-B??--EE 2ECJ|A PF13921.1_Myb_DNA-bind_6_seed 39 143 !Q:0,1|9,12|19,26|28,31|33,34|36,47|52,56|60,61|63,63|65,75|77,77|79,81|83,83|89,90|92,125|131,134|136,136 Q:2,8|13,18|27,27|32,32|35,35|48,51|57,59|62,62|64,64|76,76|78,78|82,82|84,88|91,91|126,130|135,135|137,142 ??HHHHHHH----HHHHHH--------H----T--S-------??---HHHH-----HHH--S?S-----------S?S--?S?HHHHT--S--??----------?---------?-?-------SSSSS--??H-HHHHHH 3OSG|A PF13923.1_zf-C3HC4_2_seed 345 92 !Q:0,0|4,5|7,7|9,11|13,17|19,19|21,22|24,25|27,28|30,31|33,37|39,39|41,41|43,43|45,45|48,50|53,54|56,57|59,60|64,75|77,78|80,86|89,90 Q:1,3|6,6|8,8|12,12|18,18|20,20|23,23|26,26|29,29|32,32|38,38|40,40|42,42|44,44|46,47|51,52|55,55|58,58|61,63|76,76|79,79|87,88|91,91 ?SSS-?S-B?-?S-----E-E--E?-T--T--S--?--E-E-E-H-HH---HH--H--H--HHH-?----------S--B----?--SS--S 2ECT|A PF13927.1_Ig_3_seed 182 139 !Q:7,7|17,27|32,34|42,52|63,86|92,92|96,96|101,109|111,116|120,120|123,124|128,131|134,136 Q:0,6|8,16|28,31|35,41|53,62|87,91|93,95|97,100|110,110|117,119|121,122|125,127|132,133|137,138 EEEEEES?SEEEEETTS?--------??EEEE---EEEEEES---------??EEEEEETTEE?----------------???????SSEEE?TTS?EEEE?--------S??----GGG?EE--EEE----EE---EE 1DN2|A PF13930.1_Endonuclea_NS_2_seed 50 186 !Q:4,4|7,7|9,12|15,15|19,23|27,30|34,35|38,38|42,55|58,91|93,95|101,101|106,107|110,111|118,119|122,122|126,131|148,148|151,152|156,156|164,165|168,170|173,173|180,180|185,185 Q:0,3|5,6|8,8|13,14|16,18|24,26|31,33|36,37|39,41|56,57|92,92|96,100|102,105|108,109|112,117|120,121|123,125|132,147|149,150|153,155|157,163|166,167|171,172|174,179|181,184 EGGG?SS-S????SS?EEE?-???TTS????EEE--EE?GGG-?-?--?------?SS-????????--????-????-???---????-??B??-EEESS?HHHH??SS-?GGGEEE??HH-HHH------SSHHHHHHHHHHHHHH?TT--SEE-EEEEEEE??TT-?-SS?SEEEEE-EEEE? 2XGR|A PF13932.1_GIDA_assoc_3_seed 60 73 !Q:4,72 Q:0,3 HHTT??????????-?????????????????????????????????????????????????????????? 3CES|A PF13936.1_HTH_38_seed 170 61 !Q:0,0|2,3|5,5|12,15|18,18|21,23|25,25|27,29|31,34|37,39|41,41|48,49 Q:1,1|4,4|6,11|16,17|19,20|24,24|26,26|30,30|35,36|40,40|42,47|50,60 ?S??S?HHHHHH----HT-HH---H-H---H?-??HH---H-HHHHHT??SHHHHHHHHHH 2LVS|A PF13938.1_DUF4213_seed 59 112 !Q:8,11|14,14|16,16|23,23|34,34|37,37|44,45|47,48|52,67|69,76|79,80|90,92|95,95 Q:0,7|12,13|15,15|17,22|24,33|35,36|38,43|46,46|49,51|68,68|77,78|81,89|93,94|96,111 HHHHHHHH----GG-G?EEEEEE?BSSEEEEEEE?SS?EEEEEE--E??GGG?---------------S?????--?SS??HHHHHHGGG--?SS-HHHHHHHHHHHHHHHH 3NPG|A PF13943.1_WPP_seed 25 109 !Q:0,4|6,7|25,28|34,35|37,40|62,66|72,72|75,75|98,108 Q:5,5|8,24|29,33|36,36|41,61|67,71|73,74|76,97 ?????S??HHHHHHHHHHHHHHHHS--??TTSTT--S????HHHHHHHHHHHHHHHHHHHHH-----HHHTS?SS?SHHHHHHHHHHHHHHHHHHHTT????-?????? 4M70|B PF13944.1_Lipocalin_6_seed 21 172 !Q:2,2|6,6|16,18|23,25|27,31|33,36|43,43|54,54|58,60|65,71|81,81|89,89|92,92|98,105|107,107|110,126|131,131|138,138|151,154|156,156|159,162|165,165 Q:0,1|3,5|7,15|19,22|26,26|32,32|37,42|44,53|55,57|61,64|72,80|82,88|90,91|93,97|106,106|108,109|127,130|132,137|139,150|155,155|157,158|163,164|166,171 GT?EEE?EEEEEEEEE---TTEE???B----?S---?EEEEEE?SSSEEEEEEE?GGG???BTTB???????EEEEEEEEE?SSSSSEE-EE-EEEEE--------E?TT??---------------EEEE-EEEEEE-ETTEEEEEEEEE----E-TT---?SS?EEEEEE 3RWX|A PF13949.1_ALIX_LYPXL_bnd_seed 97 503 !Q:2,2|4,4|6,12|14,15|17,18|22,23|25,25|31,33|35,35|38,38|41,49|62,63|78,78|96,96|99,100|103,103|105,111|116,118|121,122|138,138|153,154|160,161|166,166|171,203|205,205|209,248|250,255|257,266|268,271|279,279|294,295|299,299|303,303|305,317|323,324|326,327|332,337|341,355|357,358|360,360|379,379|397,398|403,412|414,414|416,428|433,439|447,450|455,455|459,459|485,485|501,502 Q:0,1|3,3|5,5|13,13|16,16|19,21|24,24|26,30|34,34|36,37|39,40|50,61|64,77|79,95|97,98|101,102|104,104|112,115|119,120|123,137|139,152|155,159|162,165|167,170|204,204|206,208|249,249|256,256|267,267|272,278|280,293|296,298|300,302|304,304|318,322|325,325|328,331|338,340|356,356|359,359|361,378|380,396|399,402|413,413|415,415|429,432|440,446|451,454|456,458|460,484|486,500 GS-T-T-------T??S--TTH--H-HHHHH---H-HH-TT---------HHHHHHHHHHHH--HHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHS-ST--TS?S?-----?HHHH---TH--HHHHHHHHHHHHHHH-HHHHHHHHHHHHHH--HTHHH--HTTS?SSHH---------------------------------H-HTT?-??-?-?--??---------------------------?S--?-?-S---------?H----HHHHHHH-HHHHHHHHHHHHHH--HHH-HHH-H----?-?--??-?HHHHH--H--HHTT------SSS-----------?-?-H--H-HHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHH--HHTT------?---T-T-?-------??--TTHH-------HHHHHHH----HHHH-HHH-HHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHS?? 2OEV|A PF13950.1_Epimerase_Csub_seed 308 66 !Q:8,10|15,17|20,24|28,28|30,31|39,46|61,61|65,65 Q:0,7|11,14|18,19|25,27|29,29|32,38|47,60|62,64 HHHHHHTS???EEEE???TT??---SEE?B??HHHHHHT??????-?HHHHHHHHHHHHHH?TTS? 1KVR|A PF13953.1_PapC_C_seed 301 139 !Q:4,4|9,9|11,12|15,15|17,19|21,33|35,41|43,46|48,56|58,58|60,61|63,74|76,80|82,82|84,85|92,93|98,100|102,102|107,107|112,122|128,134 Q:0,3|5,8|10,10|13,14|16,16|20,20|34,34|42,42|47,47|57,57|59,59|62,62|75,75|81,81|83,83|86,91|94,97|101,101|103,106|108,111|123,127|135,138 EEEE-ETTE-E??TT?E---E-------------E-------E----S---------S-S--S--------?---E-----E-E??GGGEEE--EEEE?--S-EEEE-EEES--????-????EEEEE-----??GGGS 3RFZ|B PF13954.1_PapC_N_seed 34 175 !Q:0,33|49,50|59,59|64,69|74,76|86,86|92,94|100,100|103,116|124,124|133,133|140,141|147,148|152,154|158,158|160,163 Q:34,48|51,58|60,63|70,73|77,85|87,91|95,99|101,102|117,123|125,132|134,139|142,146|149,151|155,157|159,159|164,174 ????????????---????-????????-?????EEEEEEEEETTEEEE--EEEEEEEE?SSTT------SEEE???HHHHHHTTB?GGGST---TTTTS?SS---------????-HHHHSTT?EEEEETTT-TEEEEE??GGGBS??STT???GGG?B????EEEEEEEEEEE 3RFZ|B PF13955.1_Fst_toxin_seed 13 21 !Q: Q:0,20 HHHHHHHHHHHHHHHHHHHHT 2KV5|A PF13958.1_ToxN_toxin_seed 31 223 !Q:0,1|6,6|17,22|24,24|27,30|32,33|37,38|43,43|46,46|51,51|58,59|63,85|91,96|100,100|103,111|121,121|124,125|129,130|134,135|140,143|147,147|150,153|168,169|178,178|188,189|192,193|198,203|210,211 Q:2,5|7,16|23,23|25,26|31,31|34,36|39,42|44,45|47,50|52,57|60,62|86,90|97,99|101,102|112,120|122,123|126,128|131,133|136,139|144,146|148,149|154,167|170,177|179,187|190,191|194,197|204,209|212,222 ??EEEE?HHHHHHHHHH-----?T-TS????T--TSS??EEEE?SS?BTTB?EEEEEE??TTS???--------------------GGGEE------EEE?TT?-------?EEEEEEGGG?EE??TTS--EEE??HHHH----HHH?HH----HHHHHHHHHHHHHH--HHHHHHHH-HHHHHHHHT??SS??HHHH------HHHHHS??HHHHHHHHHHH 4ATO|A PF13964.1_Kelch_6_seed 179 116 !Q:1,4|6,7|10,11|14,15|18,20|22,23|25,26|28,28|32,35|37,37|40,50|53,53|55,57|61,61|64,67|70,71|73,74|76,77|79,80|83,83|85,87|89,100|102,105|107,115 Q:0,0|5,5|8,9|12,13|16,17|21,21|24,24|27,27|29,31|36,36|38,39|51,52|54,54|58,60|62,63|68,69|72,72|75,75|78,78|81,82|84,84|88,88|101,101|106,106 E----S?-EE--EE--ET---T--E--E-EEE--??E-ES-----------SS?B???EEE-EE----TT--T--T--E--EE-E---E--?-----?--?S----S----?---? 1U6D|X PF13969.1_Pab87_oct_seed 6 112 !Q:4,4|17,17|22,22|43,44|48,49|51,51|60,68|89,94 Q:0,3|5,16|18,21|23,42|45,47|50,50|52,59|69,88|95,111 HHHH?HHHHHHHHHHTT?EEEE?GGGSSEEEEEEETTEEEEEE??SSS??E-EEEEEEEE?--------SSEEEEEEEETTEEEEEEEE------EETTEEEEEETTEEEEE 2QMI|A PF13970.1_DUF4221_seed 25 492 !Q:0,22|24,43|50,51|54,56|63,64|68,77|79,80|87,88|90,100|109,109|113,115|119,120|131,131|139,139|143,143|148,148|151,155|158,158|168,168|181,181|184,185|192,197|200,202|204,216|219,220|223,226|229,231|234,234|243,247|252,253|263,263|272,273|280,280|282,283|285,292|294,300|305,318|320,323|328,330|333,334|346,346|352,358|360,360|362,363|365,370|373,373|378,378|380,384|388,402|406,409|413,416|420,420|424,427|430,430|433,433|453,458|462,462|466,467|469,470|472,474|481,481|484,485 Q:23,23|44,49|52,53|57,62|65,67|78,78|81,86|89,89|101,108|110,112|116,118|121,130|132,138|140,142|144,147|149,150|156,157|159,167|169,180|182,183|186,191|198,199|203,203|217,218|221,222|227,228|232,233|235,242|248,251|254,262|264,271|274,279|281,281|284,284|293,293|301,304|319,319|324,327|331,332|335,345|347,351|359,359|361,361|364,364|371,372|374,377|379,379|385,387|403,405|410,412|417,419|421,423|428,429|431,432|434,452|459,461|463,465|468,468|471,471|475,480|482,483|486,491 -------------??------??T--------------------TSEEEE--EE---EEEEEE??TTS?---------S??SSEEEE--E-----------ETTEEEEE-EEE--?STT??EEEEEETTTT-EEEEEEE?BSS-STTB?TT??--?EE-ESSSTTSEE-EEEGGGTEEEEE?TT??EEEEEE?---??TT---S------???????BT--TT----TB??-EE-ETTEEEEE??--?SSSS??GGGGGGSEE-EEEEETTT??EEEEEE-E??S-?????-?S-------SEEE-----?----?--?E----EEEE---ET--TTTEEEEEETT?SEEEE-------E-S--S------SS?EEEE-E??--?TTS-----?????---??EEG----GGT----HHH-HHH----HH-HS?EEEEEEEETTTTEEEEEEE??????TTS?TTS??T--T-??EEEEEE?TT??EEEEEE 3S9J|A PF13972.1_TetR_seed 102 176 !Q:11,13|16,31|34,37|68,68|78,78|101,104|108,108|111,112|131,132|137,145|154,155|167,167 Q:0,10|14,15|32,33|38,67|69,77|79,100|105,107|109,110|113,130|133,136|146,153|156,166|168,175 HHHHHHHHHHT???SS----???---------SH----HHHHHHHHHHHHHHHHTHHHHHSHHHHHHT?HHHHHHHHH-HHHHHHHHHHHHHHHHHHTTSB?-??GGG-HH--HHHHHHHHHHHHHHHHHH--HHSS???----??HHHHHHHH--HHHHHHHHTTB?HHHHHHHH 3RH2|A PF13977.1_TetR_C_6_seed 258 157 !Q:1,4|18,18|23,23|25,26|28,30|35,35|44,44|47,47|49,51|61,61|75,79|84,87|91,91|94,95|111,113|117,117|121,124|126,130|134,136|142,144 Q:0,0|5,17|19,22|24,24|27,27|31,34|36,43|45,46|48,48|52,60|62,74|80,83|88,90|92,93|96,110|114,116|118,120|125,125|131,133|137,141|145,156 H----HHHHHHHHHHHTS-HHHH?G--G---GHHH-HHHHHHHT-TT?H---HHHHHHHHH-HHHHHHHHHHHHH-----HHHH----HHT?TT??HHHHHHHHHHHHHHH---HHH-HHH?---T-----TSS?--HHHHH---HHHHHHHHHHHT 2GFN|A PF13979.1_SopA_C_seed 9 180 !Q:2,2|15,15|17,18|20,21|29,29|37,42|46,46|51,52|65,65|69,69|94,95|98,100|118,118|124,124|137,138|140,146|148,151|166,166|175,175|179,179 Q:0,1|3,14|16,16|19,19|22,28|30,36|43,45|47,50|53,64|66,68|70,93|96,97|101,117|119,123|125,136|139,139|147,147|152,165|167,174|176,178 TT?HHHHHHHHHHTT?S??S??TTSHHHH-HHHHHHH------GGG?GGGS??HHHHHHHHHHTT?TTS?HHHHHHHHHHHHHHHHHHTSTTTT??SS???HHHHHHHHHHHHHHHHH?GGGSS?HHHHHHHHHHHS??S???----S?--?SHHHHHHHHHHHHH?HHHHHHHS?GGG? 3NAW|A PF13981.1_SopA_seed 14 162 !Q:14,15|22,23|30,31|44,44|49,49|68,76|80,85|95,95|99,104|106,106|114,115|129,132 Q:0,13|16,21|24,29|32,43|45,48|50,67|77,79|86,94|96,98|105,105|107,113|116,128|133,161 HHHHHHHHHHHHHT??TTTTSS??HHHHHH--HHHHHSSTTTTT?HHHH-HHHHHHHHHHHHHHHHHH---------TTS??????HHHHHHHHH-HHH------H?HHHHHHT--HHHHHHHHHHHTT----STTTHHHHHHHHHHHTTSTTTHHHHTSTT 3NAW|A PF13987.1_YedD_seed 10 115 !Q:0,6|10,10|15,16|18,19|27,27|34,34|69,70|94,95|110,114 Q:7,9|11,14|17,17|20,26|28,33|35,68|71,93|96,109 ???????TTT?EEEE??S??TTSSSTT?EEEEEE?TTSEEEEEEESSSEEEEEEEEEEETTEEEEEETT??EEEEEEETTEEEETTEEEEEESS??HHHHHHHHHHHTTS????? 4HWM|A PF13995.1_YebF_seed 23 94 !Q:1,5|7,7|10,11|31,31|34,36|38,42|44,46|49,50|54,57|67,68|75,80|92,92 Q:0,0|6,6|8,9|12,30|32,33|37,37|43,43|47,48|51,53|58,66|69,74|81,91|93,93 S?????S?SS??HHHHHHHHHHHHHTTTTTS?SS??-S?????S?-?EE??GGG?---EEETTEEEE??EESSSS??????EEEETTTTEEE?S 4AEQ|A PF14000.1_Packaging_FI_seed 13 140 !Q:0,88|90,91|99,99|101,103|106,106|111,111|114,114|116,116|118,118|121,121|126,126 Q:89,89|92,98|100,100|104,105|107,110|112,113|115,115|117,117|119,120|122,125|127,139 -------------------------------------------------------------------------------?????--???S??EEEEESS?B???EE?SSSS?EE-S?B?TT?EEEE?HHHHHHHHHHTSE 2LSM|A PF14008.1_Metallophos_C_seed 130 119 !Q:2,2|8,9|11,13|16,29|31,33|35,38|40,48|52,52|54,54|56,59|62,68|76,76|88,88|90,91|93,95|97,108|110,111|113,114 Q:0,1|3,7|10,10|14,15|30,30|34,34|39,39|49,51|53,53|55,55|60,61|69,75|77,87|89,89|92,92|96,96|109,109|112,112|115,118 TS?EEEEE??S??-TT-???---??-----B?--S----S----?---?TTE-E-E----EE---?-??EEEEEEE?SSSEEEEEEEE-T--T---S---------?--T--T??SEEE 4KBP|A PF14010.1_PEPcase_2_seed 27 590 !Q:0,1|6,8|10,20|23,26|40,40|46,49|55,55|59,61|75,76|79,80|91,93|98,98|116,116|122,128|131,131|133,134|141,142|160,172|178,178|181,183|194,195|212,212|219,221|238,238|262,262|270,271|278,280|283,283|288,288|295,296|301,301|309,309|327,333|370,372|374,374|376,392|400,402|406,410|416,416|418,420|422,427|440,441|456,458|462,462|464,464|488,489|492,499|506,506|526,532|540,540|560,560|567,567|588,589 Q:2,5|9,9|21,22|27,39|41,45|50,54|56,58|62,74|77,78|81,90|94,97|99,115|117,121|129,130|132,132|135,140|143,159|173,177|179,180|184,193|196,211|213,218|222,237|239,261|263,269|272,277|281,282|284,287|289,294|297,300|302,308|310,326|334,369|373,373|375,375|393,399|403,405|411,415|417,417|421,421|428,439|442,455|459,461|463,463|465,487|490,491|500,505|507,525|533,539|541,559|561,566|568,587 ??SEEE???S??---------SS????TTTHHHHHHHHTS?GGGTS????EEEEE?SSB???TTHHHHHHHHHHT--TT??BTTTBEEEEE???TTTS?HHHHHHHHHHHHHHHHH-HHHHH-------SS?S??EEEESS??SHHHHHHHHHHHHHHHH-------------HHHHH?SS???TTSSEEEEEE??HHHHHTTHHHHHHHHH-HHHHTT???SEEEEEEESHHHHHHH?HHHHHHHHHHHHHHHHHHHHHHT?EEEEEEE??SSGGGT???TT?HHHH-HHHTTT??EEEE?HHHHHTT?HHHHHHHHHHHHHHGGG???????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS???S?B??????????????-??HHHHHTT???HHH-----HHHHH?S???S??????HHHHHHHHHHTT??GGGTTHHHHHHHHH---HHH?H-HHHHHHHHHSTTHHHHHHHHHTT??TT--------TTTTTS?HHHHHHHHHHHHHHHHHTT???---?HHHHHHH?HHHHHHHHHHHHHHHHHHS?HHHHHH?HHHHHHHHHHHHHHHHHHTS?? 3ODM|A PF14031.1_D-ser_dehydrat_seed 98 259 !Q:0,0|13,18|26,27|32,32|36,59|66,66|72,75|78,81|83,100|102,103|105,136|142,146|149,149|153,176|178,191|194,200|202,232|235,235|241,241|251,251|258,258 Q:1,12|19,25|28,31|33,35|60,65|67,71|76,77|82,82|101,101|104,104|137,141|147,148|150,152|177,177|192,193|201,201|233,234|236,240|242,250|252,257 ?EEEEEEEEEEEE------TTEEEES??TTTS?GGG----------?-----?------?EEEEEE?TTSSS?---EE--??G------------------G--G------------------------------??EEEEE-?---SS?EEE------------------------E--?----------?TT------?S---------------------?--------?TT?EEEEE?SSGGGGGGG?SEEEEE? 3ANV|A PF14032.1_PknH_C_seed 68 265 !Q:0,3|12,18|23,26|30,30|33,33|35,36|39,39|41,41|43,43|45,45|47,58|60,61|73,73|84,94|102,109|111,111|116,116|120,120|128,128|139,140|153,153|159,169|180,182|184,185|188,191|203,210|214,215|232,242|246,246|250,252 Q:4,11|19,22|27,29|31,32|34,34|37,38|40,40|42,42|44,44|46,46|59,59|62,72|74,83|95,101|110,110|112,115|117,119|121,127|129,138|141,152|154,158|170,179|183,183|186,187|192,202|211,213|216,231|243,245|247,249|253,264 ????GGGGGGGS-----??HHHH----HHH-HT?S??EE?S?B?S?B-----------?S??EESSGGGHHHH?SSBHHHHTTS------???--EEEEEEE--------E?SSTT?SEE-EEEEEEE?SSHHHHHHHH--HHHHHHHHTTTT?EEEEE-----------ETTEEEEEEE???B??TT---?EEEEEEESSTT?------?EEE--EEEEEETTEEEEEEEE-----------ESS?SSH---HHHHHHHHHHHH 4ESQ|A PF14052.1_Caps_assemb_Wzi_seed 92 760 !Q:9,14|31,34|36,38|46,53|65,65|67,74|82,83|87,88|91,93|96,131|141,158|166,168|176,177|182,185|188,205|208,224|226,227|231,231|234,234|250,252|257,257|259,265|267,268|272,272|276,278|288,292|300,300|311,314|317,336|342,352|365,366|368,375|388,389|391,404|407,415|420,451|468,470|489,491|493,512|525,530|533,533|537,538|546,546|550,557|561,570|572,572|575,576|582,583|593,593|596,623|626,628|639,646|649,650|662,662|665,674|677,679|683,683|685,697|706,709|713,719|722,725|741,741|744,744|747,748|751,751 Q:0,8|15,30|35,35|39,45|54,64|66,66|75,81|84,86|89,90|94,95|132,140|159,165|169,175|178,181|186,187|206,207|225,225|228,230|232,233|235,249|253,256|258,258|266,266|269,271|273,275|279,287|293,299|301,310|315,316|337,341|353,364|367,367|376,387|390,390|405,406|416,419|452,467|471,488|492,492|513,524|531,532|534,536|539,545|547,549|558,560|571,571|573,574|577,581|584,592|594,595|624,625|629,638|647,648|651,661|663,664|675,676|680,682|684,684|698,705|710,712|720,721|726,740|742,743|745,746|749,750|752,759 HHHHHHTTS????-?SEESEEHHHHHHHHHT????S---HHHHHHH--------HHHHHHHHHHT?S--------EEEEEEE--ESS??SS???TT?--??-------------------------------SEEEEEEEE------------------EEEEETT---EEEEEEE--EEEE----EE------------------SS?---------------?S-?SEE?TT?EEEEEETTEEEEEEE???EESS?S-------S??SSS?SSS???EEEEEEESS?????SGGGGGG?SEEEEEEEEE?---SS--------?-----------TTSSS?----------EEEEEEEEEEEE--T--------TEEEEEEEEEEE??T--------------TS-??-----?TTTS?--??????-------??????----??????EEEEEEEEEEESHHHH???EEEEEEEEEEEEETTEEE---E--------------------EEEEEEEEEEEE-----?SS?EEE--EEEEEEE?SBT--------TTB?---------S?TT??SSSTT?-SEETTEESS?TT---------------------------?TT--?EEEEEEEEEE-------?TT??EEEEEEEEEEE?TT?-?-------TT--?SSS?S?------------EEEEEEEE----EEE-------EE----EETTEEEEEEEEEEE?SS?SS-?SE-EEEEEEEE 2YNK|A PF14059.1_DUF4251_seed 50 191 !Q:0,19|48,67|71,71|75,76|81,81|96,98|101,101|104,105|109,111|129,129|131,131|135,135|144,144|146,147|149,149|151,151|159,159|163,163|176,177|179,183 Q:20,47|68,70|72,74|77,80|82,95|99,100|102,103|106,108|112,128|130,130|132,134|136,143|145,145|148,148|150,150|152,158|160,162|164,175|178,178|184,190 ????????????????????HHHHHHHHHHHHHHHHHTEEEEEEEEEE?-------------------TTS?EEE??GGGS-EEEEETTEEEEEEE---EE?SS?-SGG---GEEEEEEEEEEEEEEEE-E?TTS?EEEEEEEE?S--S?E-EEEEEEE?TTS?EEEEEEEETTSS??E-----EEEEEEE 4GDZ|A PF14064.1_HmuY_seed 83 526 !Q:0,1|16,68|75,75|78,81|83,84|92,94|101,101|103,121|125,126|128,154|162,170|172,172|175,177|179,180|183,265|276,276|278,278|284,286|294,294|298,377|389,461|463,463|468,472|477,480|483,483|485,485|496,496|499,503|505,517 Q:2,15|69,74|76,77|82,82|85,91|95,100|102,102|122,124|127,127|155,161|171,171|173,174|178,178|181,182|266,275|277,277|279,283|287,293|295,297|378,388|462,462|464,467|473,476|481,482|484,484|486,495|497,498|504,504|518,525 ??TTEEEEEETTTTEE-----------------------------------------------------EEEETT?TT????S??SEEEETT---EEEESS?E-------------------EEE-?S?--------------------------SSHHHHH---------T?SS???S??EE--?--------------------------------------------------------------------------------EEEEEEEEEE?S?SSSSS--?EEEEEEE?TTG--------------------------------------------------------------------------------GGGEEEETTSS-------------------------------------------------------------------------S?EEEE???-?EEEE?---TT-S?EEEEEEEEEE?TT?---?E-------------EEEEEEEE 3H8T|A PF14099.1_Polysacc_lyase_seed 54 445 !Q:7,7|11,11|17,17|19,20|22,22|28,53|57,57|62,79|87,94|97,122|124,125|130,133|152,154|157,157|160,178|180,180|192,192|195,197|201,247|258,264|277,300|305,306|318,319|321,322|325,325|335,335|338,345|355,364|367,368|378,379|384,401|404,408|416,416|425,426|429,430|432,434|445,445 Q:0,6|8,10|12,16|18,18|21,21|23,27|54,56|58,61|80,86|95,96|123,123|126,129|134,151|155,156|158,159|179,179|181,191|193,194|198,200|248,257|265,276|301,304|307,317|320,320|323,324|326,334|336,337|346,354|365,366|369,377|380,383|402,403|409,415|417,424|427,428|431,431|435,444 EEEEESS?STT?SEEEE?T--T?EEEEE--------------------------SSS?SSTT-----------------?EEEEEEE------??TT??------------------------S??EEEE----EEEEEEETTEEEEEEEEE---EE?TT??---------------??S-SEEEEEEEEEE?TT???SSS-----------------------------------------------SEEEEEEEEE-------ETTEEEEEEEEE??----------------------BTTB??EEEEEEEEEEE??T--TS?EEEEEEEEE?SS--------TTEEEEEEE----------TT--EEEEEEEEE??SBSS----------------??EE-----EEEEEEE?HHHHHHSS??SS??E---EEEEEEEEEE- 3INA|A PF14113.1_DUF4285_seed 48 247 !Q:2,5|9,9|20,27|31,42|45,45|49,49|53,61|65,68|78,78|82,82|84,84|86,104|110,111|118,134|140,141|146,146|149,157|160,162|168,171|177,182|187,238|247,247 Q:0,1|6,8|10,19|28,30|43,44|46,48|50,52|62,64|69,77|79,81|83,83|85,85|105,109|112,117|135,139|142,145|147,148|158,159|163,167|172,176|183,186|239,246 TS????HHH-HHHHHHHHTT----????TTS------------SS?EEE?TTS--------?EEE?--?HHHHHHHHH-HHS?S?S-------------------EEEES??GGGGTT---------------??EEEEE--EEES?SS?--------SE---EEEEE---?SSSBT------TGGG???????------------------------------------------???EEEEEEEE- 4BI4|A PF14156.1_AbbA_antirepres_seed 6 64 !Q:0,2|4,5|7,9|25,26|42,45 Q:3,3|6,6|10,24|27,41|46,63 ???S??S???TTTTHHHHHHHHSSS??HHHHHHHHHHHHHTT????SSHHHHHHHHHHHHHTTT 2LZF|A PF14157.1_YmzC_seed 7 74 !Q:0,26|31,31|40,46|71,73 Q:27,30|32,39|47,70 ?????????-????-----????????EEEE?STTEEEEE-------ETTEEEEEEEETTTTEEEEEEEEE??? 3KVP|A PF14171.1_SpoIISA_toxin_seed 7 276 !Q:0,108|139,139|144,147|178,178|191,208|211,211|223,224|227,227|237,237|251,251|254,256|274,275 Q:109,138|140,143|148,177|179,190|209,210|212,222|225,226|228,236|238,250|252,253|257,273 -----------------------------------------------------------------------------------------------------???--???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHS?EEEE----ESSHHHHHHHHHHHHHHHHHTTTSEEEEEE?SSHHHHHHHHTT------------------SS?HHHHHHHHHTT??EE?TTSSEEEEE-EEETTEEEEEEEE?SS???HHHHHHHHHHHHHHHHH?? 3O6Q|A PF14185.1_SpoIISB_antitox_seed 5 57 !Q:0,13|16,16|22,24|29,34|51,56 Q:14,15|17,21|25,28|35,50 ???????????-??SS?EEEEE???SEEE??????HHHHHHHHHHHHHHTT?????? 3O6Q|B PF14186.1_Aida_C2_seed 11 159 !Q:0,9|12,13|24,25|31,31|42,42|46,46|50,51|54,55|57,59|71,71|76,76|79,79|84,84|86,86|88,88|117,118|121,124|129,130|135,136|139,141|143,144|147,147|151,152 Q:10,11|14,23|26,30|32,41|43,45|47,49|52,53|56,56|60,70|72,75|77,78|80,83|85,85|87,87|89,116|119,120|125,128|131,134|137,138|142,142|145,146|148,150|153,158 ??????????TT??EEEEEEEEEE-?TTGGG?EEEEEEEEEE?TTS?BSS??EE??S?--SEEETTEEEEE-EEEE?SS?GGGS?T-T?EEEEEEEEEETTTTEEEEEEEEEEEGGG??SE----EEEE??EESS??TT?-?S??BS?SSS??EEEEEE 2QZ5|A PF14200.1_RicinB_lectin_2_seed 49 187 !Q:3,3|9,11|13,16|18,27|30,34|36,42|47,49|52,53|55,58|60,65|72,72|74,75|79,79|85,96|100,100|106,107|109,110|112,113|115,118|122,122|126,128|131,138|142,142|146,146|148,151|153,158|161,161|167,175|177,179|182,182 Q:0,2|4,8|12,12|17,17|28,29|35,35|43,46|50,51|54,54|59,59|66,71|73,73|76,78|80,84|97,99|101,105|108,108|111,111|114,114|119,121|123,125|129,130|139,141|143,145|147,147|152,152|159,160|162,166|176,176|180,181|183,186 GGG?EEEEE---E----E----------TT-----E-------EEEE---ET--T----T----??EEEEGG-G??STT?BEEEE-????------?GGG?EEEEE-?S--S--S--?-EEE-EET---TT-?----?-EEE-EGG-G-?-?S------TT?BEEEE??---??-?G---GG?EEEE 2X2T|A PF14203.1_DUF4319_seed 27 73 !Q:0,2|13,15|29,29|34,37|40,44|59,60|70,70 Q:3,12|16,28|30,33|38,39|45,58|61,69|71,72 ???HHHHHHHHHH??-SHHHHHHHHHHHS-TTTS---?HH-----HHHHHHHHHHHHTT??HHHHHHHSS?TT 2L7K|A PF14204.1_Ribosomal_L18_c_seed 90 118 !Q:0,4|19,19|23,23|27,27|30,30|37,38|45,46|57,117 Q:5,18|20,22|24,26|28,29|31,36|39,44|47,56 ?????SSSSSSHHHHHHHT?SSS?TTT?SS?EEEEET--TEEESS??SHHHHHHHHH??------?????-????-----------????--??----???????????????????? 1S1I|E PF14226.1_DIOX_N_seed 783 281 !Q:0,1|5,5|7,16|20,20|22,25|28,31|35,40|42,44|47,51|53,53|55,55|57,59|70,70|72,74|77,79|82,85|87,93|95,101|103,103|111,111|117,117|119,119|121,121|123,123|126,128|130,130|134,134|136,140|142,147|149,152|155,157|161,165|167,169|172,180|183,184|186,206|208,209|212,212|214,214|219,219|221,230|232,239|242,243|245,270|274,276|278,279 Q:2,4|6,6|17,19|21,21|26,27|32,34|41,41|45,46|52,52|54,54|56,56|60,69|71,71|75,76|80,81|86,86|94,94|102,102|104,110|112,116|118,118|120,120|122,122|124,125|129,129|131,133|135,135|141,141|148,148|153,154|158,160|166,166|170,171|181,182|185,185|207,207|210,211|213,213|215,218|220,220|231,231|240,241|244,244|271,273|277,277|280,280 ??EEE?T----------TTT?S----SH----HHH------H---HH-----H-H-H---HHHHHHHTSE-E---EE---ES?---S---??--H-------H-HHHHHHH-HHHHH-H-T-S?HH---H-HGG-G-----B?-----B----GG---GTB?---?E---EE-??---???ST--T?-----------------???S-?EE-E-EEEE-E----------S--------GG--G------------------------??GGG---S??S 2IVI|B PF14231.1_GXWXG_seed 50 64 !Q:9,10|15,16|25,25|57,57|59,61 Q:0,8|11,14|17,24|26,56|58,58|62,63 HHHHTTSEE??GGGG?-EEEEEEES?TTSHHHHHHHHTTEEEEEEEETTEEEEEEEE?T---TS 4MVE|A PF14232.1_DUF4334_seed 50 72 !Q:1,4|37,40|52,61|64,64 Q:0,0|5,36|41,51|62,63|65,71 T--??EEEEEEEETTEEEEEEEESSSSEEEEEEEEET----TEEEEEEEETT---------?SS?EEEEEEE 4MVE|A PF14246.1_TetR_C_7_seed 164 73 !Q:1,1|3,4|6,7|22,22|25,25|29,29|34,49|54,57 Q:0,0|2,2|5,5|8,21|23,24|26,28|30,33|50,53|58,72 T?B?-S??HHHHHHHHHHHHHH-HH-THH-HHHH----??----????--HHHH----HHHHHHHHHHHHHHH 3BHQ|A PF14254.1_DUF4348_seed 14 290 !Q:0,62|78,78|87,87|94,94|99,99|104,104|108,112|135,135|138,138|175,180|183,184|195,195|216,216|227,227|235,241|252,255|258,258|271,272 Q:63,77|79,86|88,93|95,98|100,103|105,107|113,134|136,137|139,174|181,182|185,194|196,215|217,226|228,234|242,251|256,257|259,270|273,289 ----------------------????-?-???-?????????????????--????????-??GGGGSHHHHHHHHHH?HHHHHHSB?SSEEEE-ETTE-EEEE?GGG?????TTTTSSEEEEEESSGGGGGGGG?TT?SEEEEEEEETTTTEEEEEEEEEETTEEEEEEEEEEE?--???SS??HHHHHHHHHH?HHHHHHTEEEEEEEEEEETT-EEEEEEEEEE?HHHHHHH???-?-?SSEEEEEESS????TT?SEEEEEEEESSS??EEEEEEEEETTEEEEEE 3SBU|A PF14259.1_RRM_6_seed 76 127 !Q:3,3|5,8|10,11|13,15|17,17|27,30|32,32|34,41|47,47|53,56|58,61|63,63|65,65|67,72|74,74|78,79|83,86|88,90|94,94|103,105|107,109|111,113|116,117|119,120|123,123|126,126 Q:0,2|4,4|9,9|12,12|16,16|18,26|31,31|33,33|42,46|48,52|57,57|62,62|64,64|66,66|73,73|75,77|80,82|87,87|91,93|95,102|106,106|110,110|114,115|118,118|121,122|124,125 EEE?S?-?-T--T-??H-HHHHHHHHT----T-S-?-----?TTGGG-GEEEE----E--?-T-T-S----?-E-EEE--EEE??--S---SHH-HHHHHHTT---T---T---EE--S--SS?EE? 2ERR|A PF14263.1_DUF4354_seed 10 132 !Q:0,32|62,63|67,67|70,70|73,75|81,81|85,85|93,93|98,98|102,102|105,105|123,124|131,131 Q:33,61|64,66|68,69|71,72|76,80|82,84|86,92|94,97|99,101|103,104|106,122|125,130 ---------------??-----------?????EEEEEEEEEEEEEETTEEEEEEEEEEEEE??SSS?EE?TT?--EEEEE?TTS?EEEEEEE?GGGG?SEE?TT?EEEEEEEEEESSSGGGG??EEEEES? 3SB3|A PF14274.1_DUF4361_seed 20 214 !Q:0,1|11,11|14,14|19,19|23,24|31,31|36,39|45,46|66,67|71,71|85,96|99,107|109,114|122,122|126,126|129,130|133,143|145,148|157,157|172,172|180,181|184,184|187,191|207,207|211,212 Q:2,10|12,13|15,18|20,22|25,30|32,35|40,44|47,65|68,70|72,84|97,98|108,108|115,121|123,125|127,128|131,132|144,144|149,156|158,171|173,179|182,183|185,186|192,206|208,210|213,213 ??EEEEEEEEE?TT?EEEE?TTE--EEEEEE-TTEE----EEEEE??SEEEEEEEETTEEEEESTT??TTS?HHHHGGGEEEEEE---------?--TT---------S------BEEEEES-STT?TT??EE----------?S--??EEEEEEEE?SSSTTEEEEEEEEE-EEEEEEE??TT?TT?????EEEEEEEEEEEEEEE-ETT??S 3P02|A PF14295.1_PAN_4_seed 64 93 !Q:0,0|3,4|8,8|12,20|23,23|25,31|33,33|43,43|48,51|57,63|68,68|70,72|74,86 Q:1,2|5,7|9,11|21,22|24,24|32,32|34,42|44,47|52,56|64,67|69,69|73,73|87,92 ?EE??EEE-EEE---------EE-S-------S-TTHHHHHHH-HSTT??--EEEEE??-----STTT-S?--S--------?----EEEEEE 2LL4|M PF14300.1_DUF4375_seed 41 144 !Q:1,1|7,7|36,36|54,55|72,72|82,82|85,86|92,92|95,102|105,109|119,120|125,126 Q:0,0|2,6|8,35|37,53|56,71|73,81|83,84|87,91|93,94|103,104|110,118|121,124|127,143 T-TSSSS?HHHHHHHHHHHHHHHHHHHHHHHHHHHS?HHHHHTSSHHHHHHTTT??HHHHHHHHHHHHHHHH-HHHHHHHHH-HT??HHHHH-HH-----?--GG-----GHHHHHHHH--HHHH--HHHHHHHHHHHHTHHHH 3VJZ|A PF14304.1_CSTF_C_seed 4 47 !Q:0,0|17,17|25,25|41,47 Q:1,16|18,24|26,40 ?HHHHTHHHHHHHHHTS?HHHHHTS?HHHHTHHHHHHHHHH??????- 2J8P|A PF14306.1_PUA_2_seed 89 243 !Q:0,2|5,6|8,12|14,24|43,45|47,48|50,51|55,55|60,70|84,85|88,89|102,103|105,117|119,126|128,128|130,134|136,139|142,142|151,152|155,155|165,166|168,169|175,175|178,179|181,186|196,196|198,198|201,214|219,219|224,225|229,229|233,234|241,242 Q:3,4|7,7|13,13|25,42|46,46|49,49|52,54|56,59|71,83|86,87|90,101|104,104|118,118|127,127|129,129|135,135|140,141|143,150|153,154|156,164|167,167|170,174|176,177|180,180|187,195|197,197|199,200|215,218|220,223|226,228|230,232|235,240 ???TT--S-----S??--------?HHHHTGGGHHHHHHHHHH---S-?E--EEE?HHHH-----------HHHHHHHTTTTTT??EE??HHHHHHHHHHSB?-T-------------T--------S?B---??S????EE?HHHHHHTT??TT?EEEEEETTT??E--EEEEE-ES??B??---?HHHHHHHHS?S?TT--------------SHHH-HHHH--HTS?SEE??EEEEES?? 1G8G|A PF14310.1_Fn3-like_seed 1123 169 !Q:4,6|10,11|13,18|20,22|24,25|27,42|44,49|51,58|60,62|71,71|73,73|75,75|77,77|79,79|86,86|88,88|90,90|93,96|98,98|100,103|105,105|109,109|111,117|119,119|121,121|123,126|128,137|141,151|154,155|161,162|165,166 Q:0,3|7,9|12,12|19,19|23,23|26,26|43,43|50,50|59,59|63,70|72,72|74,74|76,76|78,78|80,85|87,87|89,89|91,92|97,97|99,99|104,104|106,108|110,110|118,118|120,120|122,122|127,127|138,140|152,153|156,160|163,164|167,168 EEEE---EEE--E------E---S--S------?---------S------S--?--??-S--?EEEEEEEE-E-E?T-T?EEEEEE-E-E?HH----H-H----H?EEE-T-------T-T-T----E----------EEE?---?------EE--EEEEE--ES--ST 3U4A|A PF14313.1_Soyouz_module_seed 16 60 !Q:0,12|15,17|29,35|38,38|41,41|44,44|46,59 Q:13,14|18,28|36,37|39,40|42,43|45,45 ?????????????EE???HHHHHHHHHHS???--??SS?EE?TT?B?????????????? 2B5L|C PF14322.1_SusD-like_3_seed 44 434 !Q:0,21|23,23|28,28|33,37|41,45|48,48|50,52|60,63|67,68|73,76|81,81|84,85|88,90|95,95|97,99|103,106|109,111|115,120|123,123|126,144|146,149|151,156|158,168|177,177|180,182|195,198|200,205|207,211|216,216|219,222|224,227|231,231|250,262|264,267|273,273|276,302|304,329|332,370|390,390|392,393|395,410|413,414|416,417|421,422|424,424 Q:22,22|24,27|29,32|38,40|46,47|49,49|53,59|64,66|69,72|77,80|82,83|86,87|91,94|96,96|100,102|107,108|112,114|121,122|124,125|145,145|150,150|157,157|169,176|178,179|183,194|199,199|206,206|212,215|217,218|223,223|228,230|232,249|263,263|268,272|274,275|303,303|330,331|371,389|391,391|394,394|411,412|415,415|418,420|423,423|425,433 ??????-????----?--????S?SSHH-HHHH-----HHH-----HH-H---HHHTSTT----TTT--THHH----HHHH-HT--SS---SEEE-S---STT----ST---THH------HH-TT------------??----?T----T------T??--?------HHHHHHHH-HH---HHHHHHHTTGGG----S??---?G-----GGHH-HH----H----HHH-HHHHHHHHHHHHHHHHHH-------------S--??HHHHT?SB?--?--??-?------------?----S??-----------?------------TT---------------?--?----?--------?--??--BHHHHHHHHHHHHHHHHHH-S??S??--------------TT--S??HHH--H-HHHHHHHHH 3IHV|A PF14323.1_GxGYxYP_seed 18 609 !Q:12,12|18,18|20,20|22,22|25,25|27,31|33,33|44,45|47,50|54,55|59,60|73,75|81,82|88,89|119,121|123,123|125,125|127,127|129,129|132,142|145,151|157,157|163,163|170,173|176,181|190,192|194,197|200,201|205,208|211,225|236,236|238,238|240,241|246,253|257,257|270,270|275,275|278,280|287,291|294,294|296,312|315,315|324,324|327,327|333,335|347,348|353,353|359,359|366,366|377,381|384,385|391,391|398,401|406,419|421,421|423,423|425,425|442,443|450,453|459,460|464,464|468,476|481,481|484,485|494,506|510,510|514,514|519,520|524,524|531,531|536,536|548,550|554,554|564,564|568,570|572,572|583,587|590,593|597,598 Q:0,11|13,17|19,19|21,21|23,24|26,26|32,32|34,43|46,46|51,53|56,58|61,72|76,80|83,87|90,118|122,122|124,124|126,126|128,128|130,131|143,144|152,156|158,162|164,169|174,175|182,189|193,193|198,199|202,204|209,210|226,235|237,237|239,239|242,245|254,256|258,269|271,274|276,277|281,286|292,293|295,295|313,314|316,323|325,326|328,332|336,346|349,352|354,358|360,365|367,376|382,383|386,390|392,397|402,405|420,420|422,422|424,424|426,441|444,449|454,458|461,463|465,467|477,480|482,483|486,493|507,509|511,513|515,518|521,523|525,530|532,535|537,547|551,553|555,563|565,567|571,571|573,582|588,589|594,596|599,608 HHHHHHHHHHHH?SEEEE-E-E?ST-H-----H-HHHHHHHHHH--H?-??EEE--ESS--HHHHHHHHHHTT???EEEEE??TTTTT??HHHHHHHHHHHHTEEEEEGGGHHHHHHTT???E-E-E-E?TT--??-------HH-------HHHHH-HGGGS?SSEEEE??--TT---??-SSSHHHHH---H----HT-?EEE????TT--??----------?HHHHHHHHTS?T-T-?EEEE??------TTS-HHHHHHHHHHTT?EEEE?TT???HHHHTT???-?TT?S----?????????--??TT?EEEEEEES?TT?HHHHH---THHHHHHTSTT--TTSS?EEEEE?TTHHHH?HHHHHHHHHH?---?TT--EEEEE?TTSSSB--??GGGS-------------?H-H-H-HHHHHHHHHHHHHHHT??EEEEEE----SSGGG-?HHH-HHH---------HHHS-TT??EEEEEETT????-------??EEE?TTS?EEEE??EEE?TTHHHH?STTS-HHHHHHHHHHS???TTS-GGGEEEEEE?TTT?-?H-HHHHHHHHTS?----TT----EEE??HHHHHHHHHH 3SGG|A PF14324.1_PINIT_seed 38 228 !Q:0,6|8,10|25,56|61,62|66,68|78,92|100,111|115,122|124,125|128,129|131,136|139,139|149,169|172,172|175,176|179,183|187,187|195,218 Q:7,7|11,24|57,60|63,65|69,77|93,99|112,114|123,123|126,127|130,130|137,138|140,148|170,171|173,174|177,178|184,186|188,194|219,227 ???????B???TTEEEEEEEEEEEE?????---------------------??--??EEEE--EEE???HHHHHHHHT?????-??????--?SEEEEEE------------EEE--------S??SS-?B?????-TT?EEEETTEEE?????????????????????EE?GG--GS???--SSS?EEEEEEE??----????-------------?EEEEEEEEE 4FO9|A PF14327.1_CSTF2_hinge_seed 52 90 !Q:0,5|7,10|14,15|27,27|41,41|45,52|60,60|66,66|77,78|87,89 Q:6,6|11,13|16,26|28,40|42,44|53,59|61,65|67,76|79,86 ??????B???-TTT??HHHHHHHHTTS?HHHHHHHHHHHHH-GGG???---??HHHHHHS?THHHH-HHHHHHHHTS??SSSTHHHH??? 4EBA|G PF14336.1_DUF4392_seed 49 414 !Q:0,13|16,18|40,46|49,65|68,69|77,78|81,83|107,107|110,110|116,117|128,130|132,132|134,135|137,192|196,196|204,204|206,207|212,212|214,214|216,216|219,220|222,227|229,230|232,236|245,246|249,250|259,259|268,268|282,291|293,293|295,296|298,298|304,304|324,354|356,356|361,362|366,368|378,379|381,381|385,385|387,389|392,393|400,400 Q:14,15|19,39|47,48|66,67|70,76|79,80|84,106|108,109|111,115|118,127|131,131|133,133|136,136|193,195|197,203|205,205|208,211|213,213|215,215|217,218|221,221|228,228|231,231|237,244|247,248|251,258|260,267|269,281|292,292|294,294|297,297|299,303|305,323|355,355|357,360|363,365|369,377|380,380|382,384|386,386|390,391|394,399|401,413 ??????--??????HH---HHHHHHHHHHHTTTHHHHHHH-------HH-----------------HT??TEEEEEE??EE---TTTTEEBSSSHHHHHHHHHHHHH-TT?EEEEE??HHHHHHHGGG???B?S--S?------------------------------------------------------?GGG?SEEEEES?B??BSSS-S?B?TT??B??----S??S?----HHHHHHHH--TT??EEEEESSS-SBTBBGGG-HHHHHHHSTTHHH----------H?B??B?SEEEE?SSHHHHHHHHHHHHHHHHT-------------------------------S?TTTT??HHH---HHHHHHHTT-?B?TTT?S?-?SE--ETTEEH-HHHHHHHHHHHHH 4DWZ|A PF14346.1_DUF4398_seed 51 141 !Q:0,24|26,28|46,47|49,50|55,63|76,76|84,84|87,94|107,109|133,134 Q:25,25|29,45|48,48|51,54|64,75|77,83|85,86|95,106|110,132|135,140 -------?----------------?S??-HHHHHHHHHHHHHHHHT--T??TTSH---------HHHHHHHHHHHH-HHHHHTT?HH--------HHHHHHHHHHHH---HHHHHHHHHHHHHHHHHHHHHHH--HHHHHH 4FM3|A PF14368.1_LTP_2_seed 72 208 !Q:0,4|6,17|19,22|25,58|62,64|67,69|72,83|86,88|90,98|101,103|107,117|127,142|152,153|156,167|171,173|175,175|178,179|185,185|189,189|194,194|196,207 Q:5,5|18,18|23,24|59,61|65,66|70,71|84,85|89,89|99,100|104,106|118,126|143,151|154,155|168,170|174,174|176,177|180,184|186,188|190,193|195,195 ???--B------------T----TB?---------------------------------HHH---HH---HH------------GG---G---------GB---SSS---?---????HHHHHHHTT------------??--HHHHHTTTT?-HH------------HHH---H-TB?-HHHHH-HHH-HHTT?S--???-----?? 1FK0|A PF14370.1_Topo_C_assoc_seed 47 84 !Q:0,26|31,31|44,45|50,50|52,52|58,61|70,74|77,83 Q:27,30|32,43|46,49|51,51|53,57|62,69|75,76 ???????????????????????????TTTS?HHHHHHHHHHTT??GGGT-S?HHHHH----HTHHHHHH---??TT??----? 1EJ9|A PF14374.1_Ribos_L4_asso_C_seed 64 82 !Q:0,0|2,7|11,11|13,13|27,30|32,32|34,45|49,49|57,57 Q:1,1|8,10|12,12|14,26|31,31|33,33|46,48|50,56|58,81 ?S??????SSS?S?THHHHHTTTGGGT????S?S????---?????TTS?HHHHHHS?THHHHHHHHHHHHHHHHHHHHHHH 3J39|C PF14382.1_ECR1_N_seed 79 53 !Q:1,2|5,6|8,13|15,15|17,20|22,23|29,35|37,37|43,43 Q:0,0|3,4|7,7|14,14|16,16|21,21|24,28|36,36|38,42|44,52 B??TT?-B???-?-T-T?-?-B-?TTEEE------?S-SSEEE?SSEEEEEET 2BA1|A PF14413.1_Thg1C_seed 152 216 !Q:13,13|34,36|47,48|61,63|68,69|75,75|81,180|185,199|202,203|210,210 Q:0,12|14,33|37,46|49,60|64,67|70,74|76,80|181,184|200,201|204,209|211,215 SHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHHTT???HHHHHHHHTT??HHHHHHHHHHHH???GGGS?-HHHHH?EEEEE------------------------------------------------------------------????????????????????????????----??EEEE??-----------??SS--HHHHHH?THHHH 3OTD|A PF14415.1_DUF4424_seed 97 408 !Q:11,11|15,15|25,61|63,64|70,72|75,78|81,81|84,84|97,98|101,143|145,190|192,194|197,198|203,204|209,209|216,216|219,219|231,237|242,300|303,303|310,310|320,322|330,330|333,333|337,339|347,347|352,352|356,357|360,386|388,389|393,393|402,405|407,407 Q:0,10|12,14|16,24|62,62|65,69|73,74|79,80|82,83|85,96|99,100|144,144|191,191|195,196|199,202|205,208|210,215|217,218|220,230|238,241|301,302|304,309|311,319|323,329|331,332|334,336|340,346|348,351|353,355|358,359|387,387|390,392|394,401|406,406 EEEEEEEEEEE?SSS?EEEEEEEEE------?------------------------------B??SSSEE???TT????TT?BS?EEEEEEETTEEE??EE-------------------------------------------E----------------------------------------------E???BG--GGTB??SEEE-EEEEEE?TT?EEEEEEEEEEE------?EEET-----------------------------------------------------------TS?EEEEEE?GGGGGSSSS???EEEEEEE?SS?EEE---GGGTSTT?STTS?BSS??EE---------------------------E??GGG?EEEEEESS????S? 4G2A|A PF14429.1_DOCK-C2_seed 45 258 !Q:0,5|17,24|28,38|41,43|56,63|65,66|68,68|71,71|74,80|82,82|85,85|88,91|94,94|97,100|108,108|124,133|136,143|154,155|159,159|161,175|186,187|190,197|201,201|209,210|218,228|247,257 Q:6,16|25,27|39,40|44,55|64,64|67,67|69,70|72,73|81,81|83,84|86,87|92,93|95,96|101,107|109,123|134,135|144,153|156,158|160,160|176,185|188,189|198,200|202,208|211,217|229,246 ??????EEEEEEEEEEE??-----?SSS-----------SS???EEEEEEEEETTS?-------B??S?EE?TT??-----S?BS?EE????TT?SS????EEEEEEE?TTSSTTEEEEEEEEE????------SS?????--?EEEEEEEESB?-TTS?B-------------??SEEEEEEEEE??HH--------HHT?HHHHTTS??BHHHHHT???????????EETTEEEEEEEEEEEEEE??????????? 3L4C|A PF14438.1_SM-ATX_seed 52 96 !Q:0,2|22,22|24,24|33,33|35,46|48,49|53,53|61,75|83,83|93,93|95,96 Q:3,21|23,23|25,32|34,34|47,47|50,52|54,60|76,82|84,92|94,94 --?HHHHHTTTTSEEEEEETTS?E-EEEEEEEE?T------------T??EEE-EEEEETT?-------------?EEEEEEE?GGGEEEEEE?S?- 2FB7|A PF14447.1_Prok-RING_4_seed 10 55 !Q:9,9|17,18|25,26|29,29|36,36|39,41|45,46|48,48|53,53 Q:0,8|10,16|19,24|27,28|30,35|37,38|42,44|47,47|49,52|54,54 HHHHHHHTB?TTTSSSB??EEEETT??EE?TTTGGG?SB--?TTT??B?EEEE?B 4AUQ|B PF14450.1_FtsA_seed 219 311 !Q:6,6|18,22|28,37|43,57|63,64|72,77|79,80|88,90|95,114|116,128|131,136|140,140|143,143|147,161|180,189|203,203|212,214|217,221|224,224|232,232|239,239|248,254|256,262|266,269|276,284|287,287|293,293|296,302|305,305 Q:0,5|7,17|23,27|38,42|58,62|65,71|78,78|81,87|91,94|115,115|129,130|137,139|141,142|144,146|162,179|190,202|204,211|215,216|222,223|225,231|233,238|240,247|255,255|263,265|270,275|285,286|288,292|294,295|303,304|306,310 EEEEEE?SSSEEEEEEET-----TEEEE----------EEEES??-------------HHHHH--HHHHHHH------T??HHHHHHH---HHHH?------------------?S--??---------TT??--??EEE-EE?TTS?------------?-EEEEEHHHHHHHHHHHHH----------HHHHHHHHHHHHH-HHHHHTTT?--SS----?TT?EEEESGG-GGSTTH-HHHHHHHH------?S?------EEE?--?GGGSSS?------??BT?HHHHT?GG-------GH-HHHHT 1JCF|A PF14461.1_Prok-E2_B_seed 15 177 !Q:1,5|11,11|13,13|15,15|25,26|34,54|62,63|66,66|71,72|78,78|80,87|92,92|96,99|102,107|114,115|118,119|125,125|134,134|136,137|141,150|152,152|162,162|167,174 Q:0,0|6,10|12,12|14,14|16,24|27,33|55,61|64,65|67,70|73,77|79,79|88,91|93,95|100,101|108,113|116,117|120,124|126,133|135,135|138,140|151,151|153,161|163,166|175,176 T-----EEEEE?S-S?TTEEEEEEE??TTSTTTT--------------------?EEEEEEE??TT-TTSS??EEEES-S??-----?BTTB?TTT---?BB??----HHHHHH??TT??HHHHH-HHHHHHHH-S??TTS?---------S?HHHHHHHHH?HHHH--------HH 2BEP|A PF14464.1_Prok-JAB_seed 111 220 !Q:15,19|23,23|33,52|64,88|90,91|95,103|113,129|136,136|149,149|151,153|155,156|163,164|167,182|184,184|191,191|193,199|203,203|207,214|219,219 Q:0,14|20,22|24,32|53,63|89,89|92,94|104,112|130,135|137,148|150,150|154,154|157,162|165,166|183,183|185,190|192,192|200,202|204,206|215,218 EHHHHHHHHHHHHHH-----TTS?EEEEEEEEE--------------------ETTEEEEEEEE--------------------?????S??SSS???-----?HHHHHHHHH-----------------HHHHHT?EEEEEEEEESSS?S---S??HHHHTT??SS----------------S?EEEEEE?S------?SSS?EEE--------EEEE? 4F7O|A PF14465.1_NFRKB_winged_seed 10 119 !Q:15,16|18,19|22,23|25,26|36,36|39,41|52,52|54,54|56,58|73,75|78,79|81,81|84,86|100,106|108,108 Q:0,14|17,17|20,21|24,24|27,35|37,38|42,51|53,53|55,55|59,72|76,77|80,80|82,83|87,99|107,107|109,118 HHHHHHHHHHTTSEE--E--HH--H--HHHHHHHHH-TS---GGGGGSTTGG-G?S-?-SGGGHHHHHHHHTT--?SS?-S?TT???SEEEETTTTEEEE???????H-HHHHHHHHHH 3U21|A PF14466.1_DUF4425_seed 7 131 !Q:0,21|24,26|50,50|53,53|58,59|62,62|64,64|67,67|76,78|80,81|90,90|93,93|95,96|105,105|107,109|112,112 Q:22,23|27,49|51,52|54,57|60,61|63,63|65,66|68,75|79,79|82,89|91,92|94,94|97,104|106,106|110,111|113,130 --------------------??SS???SSEEEEEEEEESGGGEEEEEEEE?EE-TTEE??EE?T-TS?EEESEEEE---E??SSEEEEEE?SS?S??EEEEEEEE?S?--TT?EEEEEEEEEETTEEEEEE 2LRG|A PF14467.1_DUF4426_seed 62 131 !Q:20,20|29,32|43,43|48,55|58,61|70,70|73,74|79,80|88,88|98,99|116,118|128,130 Q:0,19|21,28|33,42|44,47|56,57|62,69|71,72|75,78|81,87|89,97|100,115|119,127 EEEEETTEEEEEEEEEGGGS?HHHHHHTT????TTEEEEEEEE-EETT--------EE?--?EEEEEEEE?TT??EEEE??EEEEETT-EEEEEEEEE??SSEEEEEEEEEEETTS-??EEEEEEEEE??? 3UC2|A PF14470.1_bPH_3_seed 68 153 !Q:1,3|6,7|13,15|18,20|23,23|25,50|65,66|71,73|92,95|97,105|110,111|114,114|120,121|124,124|127,127|130,132|136,137|141,141|143,143 Q:0,0|4,5|8,12|16,17|21,22|24,24|51,64|67,70|74,91|96,96|106,109|112,113|115,119|122,123|125,126|128,129|133,135|138,140|142,142|144,152 S?--TT??EEEEE---EE---TT-E--------------------------EEEEESSEEEEEEE--ESSS?-?EEEEEEEEGGGEEEEEEE--??S---------STTS?-EE-EEEEE--TT?SS?EE---EEE-?BTS?H-HHHHHHHHH 3HSA|A PF14478.1_DUF4430_seed 123 140 !Q:0,0|5,10|15,19|21,24|27,30|34,35|37,50|54,57|63,65|68,72|74,74|76,89|94,94|97,101|107,107|109,109|113,114|116,121|125,125|127,130|133,133|135,135 Q:1,4|11,14|20,20|25,26|31,33|36,36|51,53|58,62|66,67|73,73|75,75|90,93|95,96|102,106|108,108|110,112|115,115|122,124|126,126|131,132|134,134|136,139 ?SBHH------HHHH-----H----TT---?EEE--E---??---------TTS--?-EEEEE---TT-----E-E-?---------?--GGGT-EE-----EEEEE-T-TEE??S-----?GGG?B?-?-TT?E-EEEE 2BB5|A PF14479.1_HeLo_seed 65 369 !Q:0,10|12,25|35,39|48,56|61,61|69,69|87,91|96,96|98,126|133,134|156,157|169,169|173,208|210,210|212,213|218,218|221,250|265,265|267,273|275,287|291,291|296,303|318,318|324,325|327,327|333,344|354,358 Q:11,11|26,34|40,47|57,60|62,68|70,86|92,95|97,97|127,132|135,155|158,168|170,172|209,209|211,211|214,217|219,220|251,264|266,266|274,274|288,290|292,295|304,317|319,323|326,326|328,332|345,353|359,368 ???????---?H--------------HHHHHHHHH-----HGGGEEEB---------GGGG-GGHHHHH-HHHHHHHHHHHHHHHHT-----TTTT?G-----------------------------GGGSSS??SHHHHHHHHHHHHHHHHHHHH--HHHHHHHTTTS?GGG------------------------------------G?B??GGGS?HH------------------------------HHHHHHHHHHHHHH-H???----S???????------EEE?SHHH--------HHHHHHHHHHHHHH-HHHTS--S?HHHHH------------HHHHHTTTT?--??HHHHHHHHHH 2WVQ|A PF14481.1_Fimbrial_PilY2_seed 9 125 !Q:0,25|54,55|58,58|62,65|73,74|77,77|85,86|90,90|98,99|113,124 Q:26,53|56,57|59,61|66,72|75,76|78,84|87,89|91,97|100,112 --------------?---------??TTEEEEEEEEEEEEGGGTEEEETTEEEE??TT?EET----TEEGGGT??TT?EEEEEEE??SSS?EEEEEEE??TTSEEHHHHHHHH???????????? 3TDQ|A PF14483.1_Cut8_M_seed 19 38 !Q:0,1|10,10|25,25|37,37 Q:2,9|11,24|26,36 ??HHHHTTSS?HHHHHHHHHHHHHH?THHHHHHHTTS? 3Q5W|A PF14486.1_DUF4432_seed 63 415 !Q:3,3|11,12|16,16|30,34|40,42|46,46|48,51|53,55|57,59|63,64|77,80|89,90|93,93|95,96|98,98|101,110|113,122|124,126|128,138|141,141|147,148|154,154|157,158|160,162|164,165|167,167|170,171|197,197|200,200|202,204|215,215|219,220|232,232|236,237|240,240|244,263|265,265|272,275|277,279|285,287|295,299|301,303|305,311|318,318|320,322|326,326|334,334|338,340|342,342|344,346|357,357|367,367|371,371|380,380|383,383|386,387|396,397|401,401|404,404 Q:0,2|4,10|13,15|17,29|35,39|43,45|47,47|52,52|56,56|60,62|65,76|81,88|91,92|94,94|97,97|99,100|111,112|123,123|127,127|139,140|142,146|149,153|155,156|159,159|163,163|166,166|168,169|172,196|198,199|201,201|205,214|216,218|221,231|233,235|238,239|241,243|264,264|266,271|276,276|280,284|288,294|300,300|304,304|312,317|319,319|323,325|327,333|335,337|341,341|343,343|347,356|358,366|368,370|372,379|381,382|384,385|388,395|398,400|402,403|405,414 GTT?EEEEEEE--SSS?EEEEEGGGTTEEE-----EEEET---TEE-E????S?-?S???GGG??TTHHHHTGGGGT??-?SEEEEEES??SS?E--E-ET----------TE----------E---E----------?TT?SGGGS??SEEEE-EE--E---S--S-TT??EEEEEEEEEEETTTEEEEEEEEEEE?TT?S---EEEEEEEEEE?SSS-?EEEEEEEEEEE?TTT??TT?EEE------------------??E-EEEEES----S---GGGGG---GSTTTTB?????T---T-?---??EEEEEE-E???TTS-EEEEEEE?SSS---S?E---EEEEEETTTS?EEEEEEEES?TTT?EEEEEEEE-SS?SS?-HHHHHHTT??EEE?TT?EEEEEEEEEE 3TY1|A PF14488.1_DUF4434_seed 39 287 !Q:6,6|9,9|12,17|19,35|51,52|56,60|63,78|84,84|89,91|96,96|99,99|101,109|112,114|128,128|134,135|137,137|139,142|147,148|150,152|154,154|158,164|166,167|174,181|186,186|190,191|197,197|199,200|204,205|210,213|216,232|236,242|247,250|255,255|258,258|265,271|273,274|277,278|280,285 Q:0,5|7,8|10,11|18,18|36,50|53,55|61,62|79,83|85,88|92,95|97,98|100,100|110,111|115,127|129,133|136,136|138,138|143,146|149,149|153,153|155,157|165,165|168,173|182,185|187,189|192,196|198,198|201,203|206,209|214,215|233,235|243,246|251,254|256,257|259,264|272,272|275,276|279,279|286,286 EEEEEE?TT?SS------S??-----------????HHHHHHHHHHHHHTT??EEE-----ES---------------?SEETT-EESS?-?HHHH-HT-T--???---?SB--?HHHHHHHHHHHTT?EEEEE??B?S----HHHH--H---S?GGG-------G--HHHHHH--------HHHH-HHH--HTTTT?T--TEE--EEEE????SS?---?------------TTH-------HHHH----HHHH-HH-HHHHTT-------S??EE--E??????T 4H41|A PF14489.1_QueF_seed 30 81 !Q:11,11|17,17|31,31|33,34|51,52|62,63|69,71|77,77 Q:0,10|12,16|18,30|32,32|35,50|53,61|64,68|72,76|78,80 EEEEEEEEEEE?SSEEE?HHHHHHHHHTTTT?B??HHHHHHHHHHHHHHHH??SEEEEEEEE??SSSEE???EEEEE?TTS 3UXJ|A PF14490.1_HHH_4_seed 189 130 !Q:0,9|21,22|24,24|26,27|36,37|39,41|43,47|51,52|58,58|65,65|67,72|76,76|86,89|91,91|93,98|100,101|104,104|119,119|123,123|126,127|129,129 Q:10,20|23,23|25,25|28,35|38,38|42,42|48,50|53,57|59,64|66,66|73,75|77,85|90,90|92,92|99,99|102,103|105,118|120,122|124,125|128,128 --?????--?HHHHHHHHHTT??H-H--HHHHHHHH--H?--T-----THH--HHHHH?GGGGGG-S------TTS?HHHHHHHHH----H-T------T??TT?HHHHHHHHHHHHHH-HHH-HH??S? 3GP8|A PF14492.1_EFG_II_seed 129 81 !Q:0,3|12,14|17,19|37,37|42,43|57,57|73,75|78,80 Q:4,11|15,16|20,36|38,41|44,56|58,72|76,77 ????SEEEEEEE---SS---SHHHHHHHHHHHHHHHH?SSEE??EETTTTEEEEEES?HHHHHHHHHHHHHTT???EE??? 1N0V|C PF14495.1_Cytochrom_C550_seed 49 168 !Q:0,3|5,13|20,27|32,32|36,37|60,64|67,67|70,73|83,84|97,97|99,99|106,106|111,112|119,119|125,126|150,153|155,155|157,164|167,167 Q:4,4|14,19|28,31|33,35|38,59|65,66|68,69|74,82|85,96|98,98|100,105|107,110|113,118|120,124|127,149|154,154|156,156|165,166 ????T---------TTTEEE?-------STTS?EEE??HHHHHHHHHHHHHHTHHHHGGG?---?TT?TT????HHHHHSSSS??SSHHHHHHHHHS?B?TTSSSB?TTTS??GGGTTT?THHHH??HHHHHHHHHHHHHHHHHHTHHHH----S?T--------TT? 3PRR|V PF14496.1_NEL_seed 37 259 !Q:1,10|14,15|43,43|46,51|67,67|82,88|91,91|94,94|109,112|119,120|123,125|153,163|166,170|172,172|190,190|193,197|201,203|206,207|219,227|242,243|254,254 Q:0,0|11,13|16,42|44,45|52,66|68,81|89,90|92,93|95,108|113,118|121,122|126,152|164,165|171,171|173,189|191,192|198,200|204,205|208,218|228,241|244,253|255,258 T?-??????-?HHH--HHHTTTTSTTHHHHHHHHHHHHHTTTT?TT?-----SHHHHHHHHHHHHHH?HHHHHHHHHHHHHT?------SS?TT?HHHHHHHHHHHHHH----HHHTTT??SS?--HHHHHHHHHHHHHHHHHHHHHHHHHSS?----------SS-----S?HHHHHHHHHHHHTTTTT?TT-????SSS???TT??HHHHHHHHHHH---------HHHHHHHHHHHHHT-?HHHHHHHHHT?HHHH 3CVR|A PF14497.1_GST_C_3_seed 199 278 !Q:8,15|19,20|26,26|42,63|91,92|107,111|116,118|121,121|123,137|144,165|170,173|175,177|181,184|187,194|199,200|203,205|210,227|231,249|254,260|263,270 Q:0,7|16,18|21,25|27,41|64,90|93,106|112,115|119,120|122,122|138,143|166,169|174,174|178,180|185,186|195,198|201,202|206,209|228,230|250,253|261,262|271,277 HHHTTGGG--------HHH--HHSSS-HHHHHHHHHHHHHHS?-------------------??HHHHHHHHHHHHHHHHHHHHHHHHHTT??SSHHHHHHHHHHHH-----HHHH--?SS?S---------------BTTBTS--?------------------?HHHH----H---HHH----HH--------HTTT--TS---HHHH------------------HHH-------------------HHHS------?HH--------HHHHHHH 3F6D|A PF14498.1_Glyco_hyd_65N_2_seed 86 469 !Q:5,20|25,27|29,31|34,35|45,49|51,51|56,56|64,66|69,73|84,84|86,89|97,119|122,123|144,144|146,161|165,169|173,186|188,190|192,194|201,213|215,221|223,235|255,256|259,272|275,284|293,295|298,306|311,316|320,320|327,327|329,329|335,336|338,338|342,342|344,357|365,365|376,396|400,401|410,410|416,416|418,420|425,432|436,440|442,442|447,450|466,466|468,468 Q:0,4|21,24|28,28|32,33|36,44|50,50|52,55|57,63|67,68|74,83|85,85|90,96|120,121|124,143|145,145|162,164|170,172|187,187|191,191|195,200|214,214|222,222|236,254|257,258|273,274|285,292|296,297|307,310|317,319|321,326|328,328|330,334|337,337|339,341|343,343|358,364|366,375|397,399|402,409|411,415|417,417|421,424|433,435|441,441|443,446|451,465|467,467 EEESS?---------------GGGS???S???TT??SHHHHHHHH-----H?EEEE?SSEEEEE???SS-----EEEEEEEETT?B??--STTSSSS??---------------------TT??HHHHGGGHHHHHHHHHHHTT?S?------------???TTS?????HHH--------------H??-B???EEEEEE----------???S---????E-------------EEEEEEETTTTEEEEEEES--SS-------------?EE----------EEEEEEET---TT---------TEEE------EEE-EESSTT?E-EEEEE??B?TTS?E--------------EEEEEEE?SSEEEEEEEE---------------------TTT??EEEEEEEE-EEGGG?S---EEEE-------?TTS-----S?EEEE----EESEEEEEEEEEESB?S? 2EAE|A PF14499.1_DUF4437_seed 17 258 !Q:5,6|11,12|16,16|20,21|30,31|35,35|43,43|46,46|49,50|56,56|73,77|79,79|87,87|90,91|93,94|102,102|105,105|111,111|115,117|120,126|129,130|133,134|138,138|148,149|152,152|154,155|160,160|170,170|174,174|177,177|183,183|188,189|195,195|197,197|223,223|229,230|232,238|243,243|253,253 Q:0,4|7,10|13,15|17,19|22,29|32,34|36,42|44,45|47,48|51,55|57,72|78,78|80,86|88,89|92,92|95,101|103,104|106,110|112,114|118,119|127,128|131,132|135,137|139,147|150,151|153,153|156,159|161,169|171,173|175,176|178,182|184,187|190,194|196,196|198,222|224,228|231,231|239,242|244,252|254,257 EGGGS??EEEE??TTS?TTS??EEEEEEEE?-TTS?EEEEEEE?TT?EE??BEESS?EEEEEEESEEEETTEE-----E?TTEEEEE?TT??B??EEEETTS?EE-EEEEE?SSS???EE-----??SS??TT??GGG?EEEEEGGGS??EE?S--SSTT?SEEEEEEEE?TTS?EE-EEEEE?SSEE??SEEEE?S?EEEEEEEEEEEETTEEEETTEEEEE?TTEEE??E-------EESS?EEEEEEESS?TTST 2QDR|A PF14501.1_HATPase_c_5_seed 80 188 !Q:1,11|21,36|38,42|44,46|48,50|52,52|59,59|61,62|64,65|68,69|76,76|78,78|80,81|83,86|88,108|112,116|119,123|126,127|131,132|134,135|137,137|139,142|144,146|148,148|161,161|163,164|168,169|172,172|177,178 Q:0,0|12,20|37,37|43,43|47,47|51,51|53,58|60,60|63,63|66,67|70,75|77,77|79,79|82,82|87,87|109,111|117,118|124,125|128,130|133,133|136,136|138,138|143,143|147,147|149,160|162,162|165,167|170,171|173,176|179,187 H-----------HHHHHHHHH----------------H--?--T---T--?E-EEEEEE-E-?S--SE--EEEEEE-E-E--S????G---------------------GGT-----TG-----GG--STT??S--S-T----T??-S?HHHHHHHHHHTT-S?-EEE--EE-EETT--EEEEEEEEE 1ID0|A PF14502.1_HTH_41_seed 19 48 !Q:0,0|5,7|18,18|34,35|37,38 Q:1,4|8,17|19,33|36,36|39,47 ?TTSB???HHHHHHHSSS?TTHHHHHTTTTTTSS??E--EETTTEEES 1V4R|A PF14503.1_YhfZ_C_seed 20 248 !Q:10,10|18,21|38,40|43,43|46,47|51,51|53,53|66,66|83,85|87,87|94,95|97,97|102,103|112,112|116,121|126,126|129,129|142,142|145,146|151,152|165,166|172,175|182,182|190,191|193,196|198,199|206,206|215,215|226,227|244,247 Q:0,9|11,17|22,37|41,42|44,45|48,50|52,52|54,65|67,82|86,86|88,93|96,96|98,101|104,111|113,115|122,125|127,128|130,141|143,144|147,150|153,164|167,171|176,181|183,189|192,192|197,197|200,205|207,214|216,225|228,243 HHHHHHTTSS?SSEEEEE????SHHHHHHHHHHHHTTT---TS?EE--EEE?S?HHHHHHHHHTTS?SEEEEEHHHHHHHHHH---S?EEEEEE??T-TSSS??EEEEEETT?GGG?----?EEEE?TT?HHHHHHHHHHHT-TS??EEEE??HHHHHHHHHHTS??EEEEE???-HHHHHH-TTEEEEE??S---?H--HHHHTT?EEEEEETT?HHHHHHHHHH??HHHHHHHHHHHHTTSS???? 2OZZ|A PF14504.1_CAP_assoc_N_seed 63 151 !Q:12,13|15,15|21,21|25,25|31,31|37,38|44,44|47,48|57,58|62,64|69,69|72,72|82,84|100,101|109,109|114,114|119,119|128,128|139,139|147,148 Q:0,11|14,14|16,20|22,24|26,30|32,36|39,43|45,46|49,56|59,61|65,68|70,71|73,81|85,99|102,108|110,113|115,118|120,127|129,138|140,146|149,150 TTSBHHHHHHHH?-S?SEEEE?TTS?EEEEE?SSGGG-?EEEEE-ET--TEEEEEEE??TTS?--BTTB?TT?BHHHHHHHS???SEEEEEETTEEEEEE??HHHHHHS?EEEE-TTEE-EEEEEETT-TTEEEEEEEE?HHHHHHH??SE 4H0A|A PF14505.1_DUF4438_seed 31 274 !Q:1,1|4,4|8,8|11,14|22,23|31,31|36,38|43,46|48,51|57,61|69,70|73,73|78,78|85,85|97,97|104,105|112,113|116,116|123,124|127,127|132,132|138,138|141,141|149,150|153,154|168,168|173,173|178,178|180,180|184,185|189,190|194,196|203,204|217,217|222,222|235,235|237,240|244,245|264,264|266,267 Q:0,0|2,3|5,7|9,10|15,21|24,30|32,35|39,42|47,47|52,56|62,68|71,72|74,77|79,84|86,96|98,103|106,111|114,115|117,122|125,126|128,131|133,137|139,140|142,148|151,152|155,167|169,172|174,177|179,179|181,183|186,188|191,193|197,202|205,216|218,221|223,234|236,236|241,243|246,263|265,265|268,273 S?EE?TTS?EE????SBSEESS??TTSBSSS?BSSS???EEEE----E?---SSGGG-----HHHHHHH??BT?EEEE?SSTTTT?EEEEEEEETTT-TEEEEE??HHHHTT??TT?EEEEEE??TT?BBTT?TTSEE?SB?HHHHTTS??EE--ETTEEEEEESEEE?GGGB?TTTT?S?TTS??EEB??SSG---GGGTSS??BTTBEEEEEEEE?SSSS?EEEEEEEEEEEE?S????STT??SEEEEEEEEETTTEEEEE?S??BGGGGT 3DCL|A PF14506.1_CppA_N_seed 12 128 !Q:22,23|29,29|37,38|40,40|42,43|51,52|56,56|58,60|63,63|85,85|87,89|95,95|105,105|108,109|115,116|118,118|122,122|125,125 Q:0,21|24,28|30,36|39,39|41,41|44,50|53,55|57,57|61,62|64,84|86,86|90,94|96,104|106,107|110,114|117,117|119,121|123,124|126,127 EEEEEEEESSHHHHHHHHTTTT??EEEEE?SSEEEEE?-T-T??EEEEEEE??TTT?B???SS?SEEEEEEEESSHHHHHHHHTT?S?-?SEEEE?SSSEEEEEE?TT??EEEEE??S?GGG?EE?SS 3E0R|A PF14507.1_CppA_C_seed 13 107 !Q:0,0|6,6|13,13|15,16|18,21|23,24|26,28|40,42|47,48|64,64|66,67|78,79|81,81|83,84|86,87|90,91|97,97|101,101 Q:1,5|7,12|14,14|17,17|22,22|25,25|29,39|43,46|49,63|65,65|68,77|80,80|82,82|85,85|88,89|92,96|98,100|102,106 ?SSEEE-EEEEEE?T--T-???S??H---HHHTTTEEEEE???TTTT??TTSBSSEEEEEEEES-S??HHHHHHHTTT--S?E--E??TT??EEEEE?TTS?EEEEE 3E0R|A PF14508.1_GH97_N_seed 243 443 !Q:2,2|6,6|12,18|21,21|24,34|36,36|44,48|59,60|64,84|89,91|96,96|98,98|108,108|113,114|117,117|122,122|136,136|141,153|173,173|175,176|178,179|181,181|186,191|199,200|204,206|209,210|215,220|222,224|226,241|244,258|267,278|280,282|289,300|303,304|306,307|312,312|319,319|321,322|324,324|326,328|336,338|340,340|342,343|351,356|366,369|372,391|393,395|397,397|399,408|414,415|431,433|440,442 Q:0,1|3,5|7,11|19,20|22,23|35,35|37,43|49,58|61,63|85,88|92,95|97,97|99,107|109,112|115,116|118,121|123,135|137,140|154,172|174,174|177,177|180,180|182,185|192,198|201,203|207,208|211,214|221,221|225,225|242,243|259,266|279,279|283,288|301,302|305,305|308,311|313,318|320,320|323,323|325,325|329,335|339,339|341,341|344,350|357,365|370,371|392,392|396,396|398,398|409,413|416,430|434,439 EE?TTS?EEEEE-------EE?TT-----------S?EEEEEEE-----TTEEEEEEEE??EEE?????------??????????GGGE---ESSS?E-EEEEEEEEE-EEEE??SS-SSSS?EEEEEEEEEEEEE-EGGG-------------TEEEEEEEEEETTEEEEEE-E--E??B-TTBS------EEEEEEE??EEE?--SS??EEEE-----?B-?-B----------------SS---------??????EEEEGGGH------------H---HHHHHH????--------SS??B??TTEE?SSEEEE?T--T-S--?EEEEEEE???S-S??EEEEEET------TTTEEEEEE?-??TT--------------------S???E-E----------ESSEE??EEEEEEESSTHHHHH-??HHHHTS-?? 2JKP|A PF14509.1_GH97_C_seed 195 131 !Q:1,1|12,12|25,29|33,34|42,42|45,45|48,49|54,54|56,56|59,60|63,67|76,76|79,79|83,86|91,91|93,95|100,102|106,107|110,110|113,113|118,118|121,121|129,129 Q:0,0|2,11|13,24|30,32|35,41|43,44|46,47|50,53|55,55|57,58|61,62|68,75|77,78|80,82|87,90|92,92|96,99|103,105|108,109|111,112|114,117|119,120|122,128|130,130 S?EEEEEEEEEE-TTTEEEEEEEET-----TSS-?EEEEEEE?TT?EE--EEEE?T-TS?-TT--??-EEEEEEEE?TT?BTT----TBTT?E---EEEE---EEE-?TT?EE-EEEE?TT?EEEEEEE-E 2JKP|A PF14511.1_RE_EcoO109I_seed 22 240 !Q:24,25|28,31|35,37|44,44|48,49|63,67|90,91|94,95|113,114|119,119|123,123|136,137|155,160|164,164|175,175|179,180|189,191|194,200|220,220|239,239 Q:0,23|26,27|32,34|38,43|45,47|50,62|68,89|92,93|96,112|115,118|120,122|124,135|138,154|161,163|165,174|176,178|181,188|192,193|201,219|221,238 HHHHHHHHHHHHHHHHHHHHHHTT??TT????TTT---HHHHHH-HTT??SHHHHHHHHHHHH-----HHHHHHHHHHHHHHHTHHHHHH??EE??HHHHHHSTTTTSGGGGG??EEEE?TTS?EEEEEEESSTTS??HHHHHHHHHHHHHHHHH-----?GGG?SEEEEEESSS?TTT??THHHHTTT???SS???????TTTEEEEETHHHHHHHTTT?TTHHHHHHHHHHHHHHHH? 1WTE|A PF14512.1_TM1586_NiRdase_seed 5 206 !Q:0,1|9,10|12,14|16,17|19,21|31,35|38,42|46,46|55,58|83,83|90,91|96,96|98,98|104,104|107,116|124,124|129,129|143,144|148,151|156,156|164,164|166,166|188,189|204,205 Q:2,8|11,11|15,15|18,18|22,30|36,37|43,45|47,54|59,82|84,89|92,95|97,97|99,103|105,106|117,123|125,128|130,142|145,147|152,155|157,163|165,165|167,187|190,203 ??HHHHHHH??B???B??S???HHHHHHHHH?????SS?????EEE?SSSSEEEE????SSHHHHHHHHHHHHHHHHHHHHTT?EEEEES??SSTT?S?EEEEE?BS??????????HHHHBSS?GGGS?HHHHHHHHHHHTS??GGG????EEEE?SSEEEEE?S?HHHHHHHHHHHHHHHHHHHSS??EEEEETTTEEEEES?? 1VKW|A PF14513.1_DAG_kinase_N_seed 9 182 !Q:0,4|6,6|8,8|22,25|34,34|47,53|56,56|70,70|73,74|86,90|92,126|128,132|134,164|180,181 Q:5,5|7,7|9,21|26,33|35,46|54,55|57,69|71,72|75,85|91,91|127,127|133,133|165,179 ?????S?S?HHHHHHHHHHHHH????HHHHHHHH-HTSGGGGGEETT-------EE?HHHHHHHHHHHTT?SS??HHHHHHHHHHS?????T-----------------------------------T?????S-----------------------------??EEHHHHHHHHHHHHS?? 1TUZ|A PF14514.1_TetR_C_9_seed 4 130 !Q:1,2|21,21|35,36|69,69|71,72|99,102|104,104|125,129 Q:0,0|3,20|22,34|37,68|70,70|73,98|103,103|105,124 S??HHHHHHHHHHHHHHHHHH?TTHHHHHHHHHHH??HHHHHHHHHHHTHHHHHHHHHHHHHHHHTTSB?S??HHHHHHHHHHHHHHHHHHHHHHHHHH????S?GGGHHHHHHHHHHHHHHHHB?---? 2QTQ|A PF14515.1_HOASN_seed 2 93 !Q:0,2|13,14|29,30|52,52|69,71 Q:3,12|15,28|31,51|53,68|72,92 ???TTSHHHHHHT??SHHHHHHHHHHSTT??HHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHH???GGGHHHHHHHHHHHHHHHHHH 3BJD|A PF14517.1_Tachylectin_seed 8 259 !Q:6,6|13,15|19,20|22,24|36,36|39,39|45,45|49,49|57,59|65,65|67,69|73,74|77,77|80,80|85,85|87,87|91,91|93,98|103,103|107,107|115,115|118,119|124,126|130,131|135,135|142,142|154,154|158,158|164,164|168,170|175,178|183,184|188,188|190,190|199,199|202,202|209,209|213,213|218,219|225,226|228,229|233,235|239,240|245,245 Q:0,5|7,12|16,18|21,21|25,35|37,38|40,44|46,48|50,56|60,64|66,66|70,72|75,76|78,79|81,84|86,86|88,90|92,92|99,102|104,106|108,114|116,117|120,123|127,129|132,134|136,141|143,153|155,157|159,163|165,167|171,174|179,182|185,187|189,189|191,198|200,201|203,208|210,212|214,217|220,224|227,227|230,232|236,238|241,244|246,258 EEEETT-EEEEES???STT??H---HHHSEEEESSS?TT?SEEEE?TTS?EEEEETT---EEEEE-S???STT??HH-HH?EEEE?S?GGG?S------EEEE?TTS?EEEEETT-EE--EEES???STT??HHH-HSEEEE?SSGGGEEEEEE?TTS?EEEEE-TTE---EEEE?-??SSTT??HHH-H?EEEESSSG-GG-EEEEEE?TTS?EEEE--ETTEE--E--EES???STT??HHHH?EEEEESSGGGEEE 3KIF|A PF14518.1_Haem_oxygenas_2_seed 140 199 !Q:3,7|12,12|15,15|17,17|20,21|25,42|48,54|63,66|69,85|87,87|89,93|95,99|102,102|104,108|115,115|118,120|122,124|126,126|129,129|138,138|140,140|143,146|151,151|154,157|164,167|169,169|172,172|174,174|176,176|178,183|187,189 Q:0,2|8,11|13,14|16,16|18,19|22,24|43,47|55,62|67,68|86,86|88,88|94,94|100,101|103,103|109,114|116,117|121,121|125,125|127,128|130,137|139,139|141,142|147,150|152,153|158,163|168,168|170,171|173,173|175,175|177,177|184,186|190,198 HHH-----HHHH-HT-T-TT?-GGG-?----------------HHHHH-------HHHHHHTT????TT---------?-???--?H-H-----H-----HH-H-----HHHHHH-HH---H-?-S-ST-HHHHHHHH-H-HH----HHHH-HH----HHHHHH----H-HH-H-T-T---?-?TTT---THHHHHHHH 1RCW|A PF14519.1_Macro_2_seed 3 294 !Q:0,16|24,24|35,45|52,52|64,81|87,88|92,95|123,125|128,129|139,146|155,157|160,160|164,164|166,167|170,170|191,191|194,194|200,201|204,204|208,210|232,232|246,248|253,253|265,266|273,274|279,279|285,285|288,293 Q:17,23|25,34|46,51|53,63|82,86|89,91|96,122|126,127|130,138|147,154|158,159|161,163|165,165|168,169|171,190|192,193|195,199|202,203|205,207|211,231|233,245|249,252|254,264|267,272|275,278|280,284|286,287 ?????????????????EEEEEES?HHHHHHHHHH???????????EEEEES?HHHHHHHHHTT????----------????EEEEE??BTT????SSHHHHHHHHHTSHHHHHHHHHHTTTS???TT??EEEEGGGGG????????TTEEEEEE???BS?SSS?S??TT?HHHHTHHHHHHHHHHHHHTS?TT?SEEEE??TT?STT???HHHHHHHHHHHHHHHHTGGGS?HHHHHHHHHHHTT???GGGS?HHHHHHHHHHT??HHHHHT??TTTS?GGGTS?TT?????? 1NJR|A PF14520.1_HHH_5_seed 554 357 !Q:1,2|5,18|20,21|23,25|27,30|32,33|35,41|43,45|47,55|58,73|75,75|77,82|85,85|88,90|92,104|108,118|120,170|172,173|175,178|180,180|182,185|187,187|189,202|206,207|210,215|217,218|220,220|222,262|265,268|270,273|275,293|296,334|336,336|338,340|346,348|350,350|355,355 Q:0,0|3,4|19,19|22,22|26,26|31,31|34,34|42,42|46,46|56,57|74,74|76,76|83,84|86,87|91,91|105,107|119,119|171,171|174,174|179,179|181,181|186,186|188,188|203,205|208,209|216,216|219,219|221,221|263,264|269,269|274,274|294,295|335,335|337,337|341,345|349,349|351,354|356,356 H--HH--------------H--H---H----H--T-------T---S---------TT--------??------H-H------HH-HH---H-------------HHH-----------S-----------------------------------------------?---H--H----H-H----H-H--------------HHH--TT?-----H--H-H-----------------------------------------HH----H----S-------------------TT-------------------------------?----?--H-H---HHHHH---H-HHHH-H 2BPF|A PF14521.1_Aspzincin_M35_seed 34 198 !Q:5,6|8,11|14,16|22,22|24,25|28,38|54,54|57,58|60,61|66,78|80,82|84,85|88,89|94,94|97,98|102,102|108,108|110,110|112,116|121,121|136,144|147,148|150,150|152,167|169,170|181,181 Q:0,4|7,7|12,13|17,21|23,23|26,27|39,53|55,56|59,59|62,65|79,79|83,83|86,87|90,93|95,96|99,101|103,107|109,109|111,111|117,120|122,135|145,146|149,149|151,151|168,168|171,180|182,197 HHHHH??S?--?HH---HHHHH?S??HH-----------HHHHHHHHHHHHHTS?GG--G--SEEE??------???--T---T??EE??TTST-TE--EEE?HHHHH-S?S-----SSTT?HHHHHHHHHHHSGG---------GT??B?S--------------??S--HHHHHHHHHH?HHHHTTBHHHHHHHHH 2X3A|A PF14522.1_Cytochrome_C7_seed 198 181 !Q:1,3|5,11|17,24|26,42|45,46|50,50|53,68|70,71|75,85|90,95|98,99|101,113|118,118|120,134|138,142|145,163|165,170|173,173|176,176 Q:0,0|4,4|12,16|25,25|43,44|47,49|51,52|69,69|72,74|86,89|96,97|100,100|114,117|119,119|135,137|143,144|164,164|171,172|174,175|177,180 E???H-------HHHTT--------T?-----?----------TT--TST-TT----------------S??SSS????-----??TTHH------HH--T------------?GGGG-T?--------------SSS-----SS-?----------------?S------SS?HH-HHEE 3BXU|A PF14523.1_Syntaxin_2_seed 91 150 !Q:5,7|14,17|29,30|33,37|39,40|48,48|50,60|84,106|140,140 Q:0,4|8,13|18,28|31,32|38,38|41,47|49,49|61,83|107,139|141,149 HHHHH---HHHHHH----HHHHHHHHHHH?-SS-----S??HHHHHHH-H-----------HHHHHHHHHHHHHHHHHHHHHHS??--------------------?SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH-HHHHHHHHH 3LG7|A PF14524.1_Wzt_C_seed 236 232 !Q:2,2|4,4|6,6|10,12|17,18|26,26|32,32|35,37|42,42|50,51|55,57|60,60|64,64|67,68|74,74|76,77|81,84|89,89|97,97|100,102|105,106|108,108|110,119|121,121|131,134|136,136|138,139|141,141|150,170|189,189|193,195|199,218|221,222|227,231 Q:0,1|3,3|5,5|7,9|13,16|19,25|27,31|33,34|38,41|43,49|52,54|58,59|61,63|65,66|69,73|75,75|78,80|85,88|90,96|98,99|103,104|107,107|109,109|120,120|122,130|135,135|137,137|140,140|142,149|171,188|190,192|196,198|219,220|223,226 TB?T-T?EEE???SEEE--EEEEEEE-TTEES?SS---EETT?EEEEEEE--EEE---SS?EEE-EE--EEEEE-E--ETT?--?EEEE-EEHHHHT-TT???EE--E?T----------T?EEEEEEEEE??--B?S--E-EEEEEEEE---------------------EEEETTTEEEEEEEEEEE-EEE---EEE-?------------------SS??EESB?-??? 2R5O|A PF14526.1_Cass2_seed 24 232 !Q:5,6|15,16|19,19|26,27|31,32|42,43|45,46|49,52|56,58|61,65|72,73|76,78|83,83|93,94|96,98|104,111|114,114|118,119|128,128|130,132|137,137|142,142|149,149|154,170|172,173|175,175|177,184|186,187|191,200|204,219|221,224 Q:0,4|7,14|17,18|20,25|28,30|33,41|44,44|47,48|53,55|59,60|66,71|74,75|79,82|84,92|95,95|99,103|112,113|115,117|120,127|129,129|133,136|138,141|143,148|150,153|171,171|174,174|176,176|185,185|188,190|201,203|220,220|225,231 EEEEE??EEEEEEEE--EE?HHHHHS--TTT??HHHHHHHHH--H--HT----GGG?-?TT---??EEEEEE??SS---STTS?EEEEEEESS??T---TTSTT?-------EE-EEE??EEEEEEEE-E---SSTT-HHHH-HHHHHH-HHHH????-????--------B??S-E--------E--EEE?--------?SSS----------------E----EEEEEEB 1JYH|A PF14527.1_LAGLIDADG_WhiA_seed 23 98 !Q:15,16|18,18|21,24|31,31|44,45|49,52|57,57|60,60|66,67|80,81|91,95 Q:0,14|17,17|19,20|25,30|32,43|46,48|53,56|58,59|61,65|68,79|82,90|96,97 HHHHHHHHHHHHEEE??T-TT?-??EEEEES?HHHHHHHHHHHH--HHH????EEEE?SS?EEEEE??HHHHHHHHHHTT??HHHHHHHHH?????HH 3HYJ|A PF14528.1_LAGLIDADG_3_seed 233 230 !Q:1,1|8,11|16,18|21,25|27,28|30,31|35,50|56,58|60,61|63,66|68,75|79,86|91,91|93,93|95,95|97,97|99,99|102,106|110,114|116,116|118,129|131,173|175,194|198,199|202,203|208,215|218,218|222,222 Q:0,0|2,7|12,15|19,20|26,26|29,29|32,34|51,55|59,59|62,62|67,67|76,78|87,90|92,92|94,94|96,96|98,98|100,101|107,109|115,115|117,117|130,130|174,174|195,197|200,201|204,207|216,217|219,221|223,229 H-HHHHHH----HHHH?--EE-----E--T--TTE----------------EEEEE---S-?H----H--------HHH--------HHHH-H-H-H-T-TT???--EEE-----E-E------------E-----------------------?-------------------S--------------------SSE--EE--EEEE----??--HH-HHH-HHHHHTG 1DQ3|A PF14529.1_Exo_endo_phos_2_seed 204 248 !Q:7,8|12,24|40,40|43,46|53,53|55,69|74,80|83,118|125,128|137,137|140,155|157,162|166,183|185,188|190,196|202,205|215,220|224,227|231,233|236,240|244,245 Q:0,6|9,11|25,39|41,42|47,52|54,54|70,73|81,82|119,124|129,136|138,139|156,156|163,165|184,184|189,189|197,201|206,214|221,223|228,230|234,235|241,243|246,247 EEEEEEE??TTS------------?SHHHHHHHHHHHHTT?SS----SEEEEE-E???----------??GGGT?------SS--------??--------------------------HHHHHH----HHHHHHHT?EE?------------??-S--??-?SEE????????----------E----E??-----EEEEE---?GGGBTTEEE------EEE---?TTS---SS-----SSB??EE 1VYB|A PF14530.1_DUF4439_seed 37 145 !Q:23,24|54,60|63,65|68,76|103,104|134,145 Q:0,22|25,53|61,62|66,67|77,102|105,133 HHHHHHHHHHHHHHHHHHHHHHS-?GGGHHHHHHHHHHHHHHHHHHHHHHHHTT???????SS???SS------???SHHHHHHHHHHHHHHHHHHHHHHHHH??SHHHHHHHHHHHHHHHHHHHHHHHHHHHS???????????- 2IB0|A PF14531.1_Kinase-like_seed 8 326 !Q:9,11|23,23|37,38|50,53|70,70|74,75|85,85|87,89|95,95|99,99|106,109|121,124|128,136|150,151|181,181|183,184|192,192|195,196|200,204|207,207|215,225|230,230|237,247|251,251|271,273|280,280|285,297|302,307|319,319 Q:0,8|12,22|24,36|39,49|54,69|71,73|76,84|86,86|90,94|96,98|100,105|110,120|125,127|137,149|152,180|182,182|185,191|193,194|197,199|205,206|208,214|226,229|231,236|248,250|252,270|274,279|281,284|298,301|308,318|320,325 EEEEEESSS???EEEEEEEEEEE?SSEEEEEEEESSS??EEEEEEEEESS-???TTHHHHHTHHHHGGGG-STT??SHHHHHHHH?B???SEEEE?TTS?SEEEEE????EEEEESEEEEE????EEH---------HHHHHHHHHHTTT--SHHHHHHHHHHHHHHHHHHHHHHHHTTEE?S??SGGGEEE?TT??EEE???--TT?EETTEEE?--????----TTTS?HHHHHH?-?????????EEE?HHHHHHHHHHHHHHHHHSS???GGGGGG?SSHH-------------HHTT??-???HHHHHHHHHHT?SSGGGS 1H1W|A PF14532.1_Sigma54_activ_2_seed 21 182 !Q:0,3|18,19|21,21|24,24|33,34|43,44|48,52|55,56|64,66|68,71|73,80|83,85|90,93|95,98|108,108|111,112|126,134|137,137|141,144|153,153|157,162|179,181 Q:4,17|20,20|22,23|25,32|35,42|45,47|53,54|57,63|67,67|72,72|81,82|86,89|94,94|99,107|109,110|113,125|135,136|138,140|145,152|154,156|163,178 ????HHHHHHHHHHHHHH--T?SS?EEEEEETT??HHHHHGGG??TTS?----EE??SSTTHHH---H---?H--------HH---HHHH----T----TTSEEEEEE?TT??HHHHHHHHHHHHH---------HT-TTT?---EEEEEEEE?TTT--????HHHHHHHHSSSEEEEE??? 1HQC|A PF14533.1_USP7_C2_seed 69 314 !Q:0,0|7,7|9,9|11,11|16,16|20,24|31,31|35,35|38,45|50,51|55,55|68,76|79,82|85,86|89,91|94,99|109,110|119,152|155,155|161,163|165,166|172,173|178,184|198,204|218,219|232,236|238,238|243,243|245,245|250,250|257,266|269,270|272,273|275,275|277,280|286,286|290,293|297,299|303,303|306,313 Q:1,6|8,8|10,10|12,15|17,19|25,30|32,34|36,37|46,49|52,54|56,67|77,78|83,84|87,88|92,93|100,108|111,118|153,154|156,160|164,164|167,171|174,177|185,197|205,217|220,231|237,237|239,242|244,244|246,249|251,256|267,268|271,271|274,274|276,276|281,285|287,289|294,296|300,302|304,305 ?EEEEEE?S-S?HHHH-HSB??---EEEEEE?TTS?EE--------EEEE??BTT?BHHHHHHHHHTT???-----?TT????EE--EE---EE------ETTEEEEEE?-TTSBGGGS--------?-----------------------??TT?EEEEE---E??GGGSS??TTTE-------EEEEEEEESSSTT------?EEEEEEEEEEETT??HHHHHHHHHHHH--???H-HHHT-T?EEEE-EETTEE----------EE??T--T-T????GGGTS?STT?---SSS???EEE-EE????---- 2YLM|A PF14534.1_DUF4440_seed 216 268 !Q:6,6|8,10|13,13|15,15|17,17|19,23|25,25|27,28|30,31|34,36|39,39|43,45|47,48|50,56|58,58|60,60|62,63|67,72|75,82|84,84|86,87|89,100|104,105|111,119|122,128|130,133|135,135|137,138|140,141|143,143|146,150|153,153|156,162|165,165|167,168|170,175|178,180|183,185|188,188|192,195|198,198|201,201|203,209|212,214|217,218|220,224|226,228|232,232|234,240|246,246|251,251|254,254|256,259|262,263 Q:0,5|7,7|11,12|14,14|16,16|18,18|24,24|26,26|29,29|32,33|37,38|40,42|46,46|49,49|57,57|59,59|61,61|64,66|73,74|83,83|85,85|88,88|101,103|106,110|120,121|129,129|134,134|136,136|139,139|142,142|144,145|151,152|154,155|163,164|166,166|169,169|176,177|181,182|186,187|189,191|196,197|199,200|202,202|210,211|215,216|219,219|225,225|229,231|233,233|241,245|247,250|252,253|255,255|260,261|264,267 HTHHHH-H---HH-H-H-H-----H-H--T?-HH---HH-HHH---E--E-------E-E-E--EEE-----?TT--------S?E--E--?---------HHH--HHHHH---------HT-------T?---E-E--E--E-EE-----EE-EE-------EE-E--E------EE---TT---EE-EEE----EE-EE-E-------EE---EE--T-----T---EEE-E-------EEEEE-EEEE-EE-E----TT--EEEE 1OHS|A PF14535.1_AMP-binding_C_2_seed 244 158 !Q:4,4|15,16|21,21|31,31|33,34|36,37|39,40|51,51|53,54|56,63|65,77|80,85|89,94|107,107|111,121|127,127|130,130|132,152|156,156 Q:0,3|5,14|17,20|22,30|32,32|35,35|38,38|41,50|52,52|55,55|64,64|78,79|86,88|95,106|108,110|122,126|128,129|131,131|153,155|157,157 TEEE?HHHHHHHHHT?-TTEE-EEEEEEEEE-E--T--T--EEEEEEEEEE?T--T-?-?-?-?H-------------HH------HHH------HHHHHHHHHHHH-HSS---?---?---EEEEE?TT?S??-----?-?-?---?--???EEE?S 2Y27|A PF14537.1_Cytochrom_c3_2_seed 85 186 !Q:6,8|11,11|15,25|28,32|35,38|40,40|46,61|67,71|73,73|75,79|82,90|92,111|116,116|120,126|129,132|134,139|141,143|149,149|151,151|154,175|178,178|180,180|182,182|184,185 Q:0,5|9,10|12,14|26,27|33,34|39,39|41,45|62,66|72,72|74,74|80,81|91,91|112,115|117,119|127,128|133,133|140,140|144,148|150,150|152,153|176,177|179,179|181,181|183,183 HHHHHS--?GG-GTS-------?---SS?-???TT---?H-HHHHH----------------HHHHH?---?H-H-----HH------??-S--------------------SSSS?TTS-------ST----T-----?S??-GGGTS?S-SS-----------?-----?--??GG-G-G-T?? 2OZY|A PF14539.1_DUF4442_seed 66 180 !Q:18,18|20,21|30,31|38,40|45,45|51,51|72,72|74,76|90,90|92,95|97,97|104,104|106,106|108,115|117,118|120,131|133,141|143,143|145,147|156,158|160,160|164,165|167,167|169,169|177,177 Q:0,17|19,19|22,29|32,37|41,44|46,50|52,71|73,73|77,89|91,91|96,96|98,103|105,105|107,107|116,116|119,119|132,132|142,142|144,144|148,155|159,159|161,163|166,166|168,168|170,176|178,179 HHHHHHHHHHHHSGGGGG-G??EEEEEETT--EEEEEE???GGGB?TTSSB?HHHHHHHHHHHHHHHHHHHS?T---TEEEEEEEEEEEE?S?-??S?EEEEEE?T-T--------S-?T------------T?-----?--E-E---EEEEEEEE---E-TTE--E-E-EEEEEEE-EE 1Q4U|A PF14540.1_NTF-like_seed 23 122 !Q:25,25|27,28|32,32|47,49|52,52|84,85|114,116 Q:0,24|26,26|29,31|33,46|50,51|53,83|86,113|117,121 HHHHHHHHHHHHHHSTTEEEEEEEE?S--STT?GGGTTSSEEEEEEE??-TT?SEEEEEEEETTEEEEEEEEEHHHHHHHHHHT??HHHHHHHHHSEEEEESTTHHHHHHHHTT???HHHHH 3C18|A PF14541.1_TAXi_C_seed 112 239 !Q:4,7|13,17|19,19|21,26|28,28|33,38|41,47|51,51|54,54|60,60|74,74|81,88|90,94|97,97|99,99|106,114|118,119|124,127|129,129|133,133|136,140|143,147|152,152|155,155|161,161|163,164|166,168|170,170|172,180|183,183|186,186|190,206|209,209|211,211|216,216 Q:0,3|8,12|18,18|20,20|27,27|29,32|39,40|48,50|52,53|55,59|61,73|75,80|89,89|95,96|98,98|100,105|115,117|120,123|128,128|130,132|134,135|141,142|148,151|153,154|156,160|162,162|165,165|169,169|171,171|181,182|184,185|187,189|207,208|210,210|212,215|217,238 SEEE??-?EEEES-----S?B?-?-??H-HHHS?----?SS?---???EEE?SS?SSEEE?HHHHHHHHHHHHH-HHHHTT------??B-????TT?S?EEESSS-??------EET--TEES??-?E-EEE?SS-----SS----?EEEE?HH-HHEEE-S--S---S-S---------EE-EE?EEE?---------------?SS?S?SEEE?STTTTTEEEEEETTTTEEEEEE 2IRZ|A PF14542.1_Acetyltransf_CG_seed 355 145 !Q:6,6|10,19|21,21|27,29|32,49|53,66|70,78|81,81|89,89|94,94|114,115|120,121|126,126|128,128|131,132|135,135|137,137|139,139|141,141|145,145 Q:0,5|7,9|20,20|22,26|30,31|50,52|67,69|79,80|82,88|90,93|95,113|116,119|122,125|127,127|129,130|133,134|136,136|138,138|140,140|142,144 EEEEES-SST----------T-EEEEE---EE------------------EES--------------SSS---------EE-EEEEEEE?SSSS?TTHHHHHHHHHHHHHHHTT?-EEEE??HHHH-H-HH--HH?G-G-G-TTT- 2H5M|A PF14543.1_TAXi_N_seed 111 343 !Q:9,20|24,31|41,42|45,45|47,47|50,85|89,91|94,98|101,102|104,114|124,132|135,147|151,155|158,159|163,163|166,167|171,172|174,175|178,178|184,184|190,190|195,196|201,209|220,225|227,227|231,240|243,244|246,247|249,275|277,278|283,283|285,285|289,291|302,302|304,305|307,308|315,316|318,331|335,335|342,342 Q:0,8|21,23|32,40|43,44|46,46|48,49|86,88|92,93|99,100|103,103|115,123|133,134|148,150|156,157|160,162|164,165|168,170|173,173|176,177|179,183|185,189|191,194|197,200|210,219|226,226|228,230|241,242|245,245|248,248|276,276|279,282|284,284|286,288|292,301|303,303|306,306|309,314|317,317|332,334|336,341 EEEEEEETT------------TTE--------EEEEEEETT-?SS?E-EE?-----------------------------------STT???SS?----EE??S-----------SSHHHHHHT??----???EE------???????EES--???EE??EEG-GG--TEE??E--EE-EEEEE-EEEEE-SSSB--EEEE---------EEEEEEEEEE------E?GGG----------GT--T??T---------------------------T??EEEE?S-SSS---SSHHHHHHHH-H--T??SEEEEE??S-------------?SSS?EEEEEE? 2BJU|A PF14544.1_DUF4443_seed 8 119 !Q:1,4|8,8|10,10|24,28|41,41|56,56|60,61|67,67|74,78|80,83|85,87|89,89|96,96 Q:0,0|5,7|9,9|11,23|29,40|42,55|57,59|62,66|68,73|79,79|84,84|88,88|90,95|97,118 B?-??EEE-E-ETTEEEEEEEESS?????HHHHHHHHHHTT?SEEEEEEEETTEEE?TTT??BGGGT?HHHHHH?---?S?--?T---T?EEEEEE?SSHHHHHHHHHHHHHHHHGGGS 2P8T|A PF14547.1_Hydrophob_seed_seed 24 92 !Q:0,0|2,9|17,23|26,27|41,41|51,52|60,60|62,64|68,69|80,81|84,90 Q:1,1|10,16|24,25|28,40|42,50|53,59|61,61|65,67|70,79|82,83|91,91 ?S?-----??GGGGGGG-------GT??TTHHHHHHHHHTS?HHHHHHHHH--HHHHHHT?S?--HHH--HHHHHHHHTT-?SS-??????S 1HYP|A PF14549.1_P22_Cro_seed 33 67 !Q:20,21|28,33|36,37|51,51|53,58|63,66 Q:0,19|22,27|34,35|38,50|52,52|59,62 BHHHHHHHHSSHHHHHHHHT??HHHHHH?----?SB??HHHHHHHHHHTTS?S???---SSTT???? 3BD1|A PF14551.1_MCM_N_seed 340 444 !Q:5,5|12,28|30,89|94,94|100,115|123,126|128,172|175,176|181,181|186,187|189,225|227,246|249,249|252,252|254,254|264,264|266,267|272,272|280,356|359,359|364,366|369,387|390,403|405,418|421,421|425,429|432,433|437,438 Q:0,4|6,11|29,29|90,93|95,99|116,122|127,127|173,174|177,180|182,185|188,188|226,226|247,248|250,251|253,253|255,263|265,265|268,271|273,279|357,358|360,363|367,368|388,389|404,404|419,420|422,424|430,431|434,436|439,443 HHHHH-HHHHHH---------------??T------------------------------------------------------------TTTS?TTHHH----------------HHHHHHH----T---?-----------------------------------------SS??EEHH-HHHT--T--?----------------------------------T--------------------TH-HH-H-HHTTHHHHH-H--HHHH-HHHHHHH-----------------------------------------------------------------------------HH?GGGT---TT-----???------?-???EE??------------S?-------------EE?GGG?-?--GG--GTT??EEEEE 3F9V|A PF14552.1_Tautomerase_2_seed 157 93 !Q:0,1|9,11|18,21|23,23|25,26|29,35|37,38|49,50|68,68|71,72|84,84|86,86|91,91 Q:2,8|12,17|22,22|24,24|27,28|36,36|39,48|51,67|69,70|73,83|85,85|87,90|92,92 ??EEEEEEE--?GGGEEE?--?T-T--SS---????S??EEEEEEEETT??HHHHHHHHHHHHHHHTT-TT??GGGEEEEEEEE?G-GGEE?B 3N4D|A PF14553.1_YqbF_seed 9 45 !Q:2,2|11,12|18,18|23,23|41,42|44,45 Q:0,1|3,10|13,17|19,22|24,40|43,43 SS?SEEEETTE--EEEBT?EEEE?HHHHHHHHHSTTEEEEE??S?- 2HJQ|A PF14554.1_VEGF_C_seed 5 59 !Q:0,1|3,8|10,13|18,18|24,24|28,29|35,35|44,44|56,58 Q:2,2|9,9|14,17|19,23|25,27|30,34|36,43|45,55 ??S??????S----STTT?TTEEE?TTT??EEESS?HHHHHHTT?EEETTTTEEES??? 4DEQ|A PF14555.1_UBA_4_seed 201 56 !Q:8,8|12,21|23,27|40,40|52,55 Q:0,7|9,11|22,22|28,39|41,51 HHHHHHHH-HHT-?--?----?H-----HHHHHHHHHTTS?SHHHHHHHHHT?--? 2G3Q|A PF14556.1_AF2331-like_seed 3 96 !Q:0,2|6,6|18,19|28,29|42,42|61,61|64,64|72,72|85,86|93,93|95,96 Q:3,5|7,17|20,27|30,41|43,60|62,63|65,71|73,84|87,92|94,94 ???EEE?HHHHHHHHHTT??SSEEEEEE??EEEEEEEEEEET-TEEEEEEEEEEEEESTTB-SS?HHHHHHS?EEEEEEEEGGGB-?HHHHHT-B?- 2FDO|A PF14557.1_AphA_like_seed 5 180 !Q:0,6|18,18|24,24|44,45|51,52|64,74|79,79|92,95|98,98|100,101|118,118|144,144|146,152|154,155 Q:7,17|19,23|25,43|46,50|53,63|75,78|80,91|96,97|99,99|102,117|119,143|145,145|153,153|156,179 ???????HHHHHHHHHHH-HHHHS?EEHHHHHHHHHHHHHHHHS??GGGTT??THHHHHTTSEE???????????EEEE?HHHHHHHHHHHS????SS-S?-THHHHHHHHHHTGGGS?HHHHHHHHHHHHHHHHHHHHHHHHH-H???????S--HHHHHHHHHHHHHHHHHHHHHHHH 2RKH|A PF14559.1_TPR_19_seed 300 115 !Q:5,10|15,18|25,27|29,29|31,34|37,41|45,49|55,56|58,62|64,65|73,73|75,75|79,81|90,90|94,99|104,105|108,110 Q:0,4|11,14|19,24|28,28|30,30|35,36|42,44|50,54|57,57|63,63|66,72|74,74|76,78|82,89|91,93|100,103|106,107|111,114 HHHTT-----?HHHH----HHHHHH---H-H----HH-----TTS----?HHHHH--H-----H--HHHHHHT-T?HHH---HHHHHTTS?GGG??----HHHH--HH---HHHH 2PL2|A PF14560.1_Ubiquitin_2_seed 85 106 !Q:0,0|12,13|15,15|18,20|24,24|41,41|43,43|47,47|49,49|52,53|55,56|60,60|65,79|89,91|94,94|100,101|103,104 Q:1,11|14,14|16,17|21,23|25,40|42,42|44,46|48,48|50,51|54,54|57,59|61,64|80,88|92,93|95,99|102,102|105,105 ?EEEEEEETTSS--S?EE---EEE?TTSBHHHHHHHHHHHT?S?TTT?B?EE--E-?SSS?EEEE?----------??--SSSBTTSSS-??TT?EEEEB??S??S 2FCS|A PF14561.1_TPR_20_seed 216 106 !Q:4,4|16,18|20,20|23,23|25,26|41,41|56,56|60,67|84,84|87,90|105,105 Q:0,3|5,15|19,19|21,22|24,24|27,40|42,55|57,59|68,83|85,86|91,104 HHTS?HHHHHHHHHHH---H?TT?H--HHHHHHHHHHHHTT?HHHHHHHHHHHHHH?TTG--------GGGHHHHHHHHHHHHH?TT---?HHHHHHHHHHHHHH? 3QDN|A PF14562.1_Endonuc_BglI_seed 3 299 !Q:17,17|50,50|62,66|70,71|74,77|99,99|103,106|109,110|118,118|129,129|139,140|142,142|146,146|153,153|157,157|159,161|163,165|170,171|173,175|179,180|182,182|185,186|191,193|195,195|200,200|203,204|224,224|227,229|241,242|251,251|255,255|265,265|267,268|272,272|276,277|291,292|298,298 Q:0,16|18,49|51,61|67,69|72,73|78,98|100,102|107,108|111,117|119,128|130,138|141,141|143,145|147,152|154,156|158,158|162,162|166,169|172,172|176,178|181,181|183,184|187,190|194,194|196,199|201,202|205,223|225,226|230,240|243,250|252,254|256,264|266,266|269,271|273,275|278,290|293,297 HHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHH-HHHTHHHHTTS?????SSS??SS????HHHHHHHTHHHHHHHHHTSTT?EEE????SS??SEEEEEE?HHHHHHTTTS?SEEEEEEEE??B?TTS?TTEEEE?GGG?B???B-??STTS??B???EEE--E?SS?-EEEE???B?SEEE?TT??EEEEEEEEEEEEEEEGGGS-TT???EEEEEEEEEEE??HHHHHTSS?GGG?GGGTTSEEE?S??TTS?TTS??EEEEHHHHTTSSS-?EEEEE? 1DMU|A PF14563.1_DUF4444_seed 20 48 !Q:9,13|22,22|25,26|31,31|34,35|40,40|46,47 Q:0,8|14,21|23,24|27,30|32,33|36,39|41,45 TTSEEEETT-----EEEEEEEE?TT??EEEE?SS-?EEEE?GGGGS?? 3BFM|A PF14564.1_Membrane_bind_seed 26 131 !Q:7,9|13,13|16,16|28,33|42,45|51,53|59,59|73,78|100,101|103,105|108,109|111,112|129,130 Q:0,6|10,12|14,15|17,27|34,41|46,50|54,58|60,72|79,99|102,102|106,107|110,110|113,128 EEEEEEE---ESS?SS?TTEEEEEEETT??---?EEEESSSS---?EEEEE???SSTTS?EEEEEEEEESSTT----??EEEEEEEEEEEETTTTEEEEE??T---TT??S--SEEEEEEETTEEEEEE?? 1YHP|A PF14565.1_IL22_seed 5 139 !Q:0,3|8,9|27,29|32,33|43,44|90,101|138,138 Q:4,7|10,26|30,31|34,42|45,89|102,137 ????GGGG??HHHHHHHHHHHHHHHHT???SS??SSSHHHHTT??TTTHHHHHHHHHHHHHHHTTTTTTTSSTTHHHHHHHHHHHHHHHT????????????HHHHHHHHHHHHHTHHHHHHHHHHTHHHHHHHHHHH? 3DLQ|I PF14566.1_PTPlike_phytase_seed 103 285 !Q:4,4|6,6|16,16|20,20|24,24|29,33|38,40|48,49|53,54|62,62|65,65|67,67|69,69|74,74|76,76|79,86|89,93|96,197|199,199|201,201|209,209|217,217|221,223|237,239|241,258|260,260|266,266 Q:0,3|5,5|7,15|17,19|21,23|25,28|34,37|41,47|50,52|55,61|63,64|66,66|68,68|70,73|75,75|77,78|87,88|94,95|198,198|200,200|202,208|210,216|218,220|224,236|240,240|259,259|261,265|267,284 EEEE?S?EEEETTEEE-EEE?GGG?TTTT?---?HHHH---HHHHHHH--HHH--TTTSEEE-EE?B?T-TSSB?S?EE--------EE--???EE-----------------------------------------------------------------------------------------------------?H-H-HHHHHTT?EEEEEEE?TTS???HHHHHHHHHHHTT?-?T------------------T?EEEEE?SSSSHHHHHHHHHHHHHH 2IMG|A PF14567.1_SUKH_5_seed 27 151 !Q:0,0|11,14|17,22|35,38|51,52|57,57|59,59|63,63|70,71|82,82|85,86|93,93|104,109|113,121|126,132 Q:1,10|15,16|23,34|39,50|53,56|58,58|60,62|64,69|72,81|83,84|87,92|94,103|110,112|122,125|133,150 ?HHHHHHHHHH????SS??????HHHHHHHHHHHT????HHHHHHHHHHTT??BTTB?B?BSS?TTSTTB--HHHHHHHHHH-HT??TTSEEE-EEETTEEEEE?-----TTS?--------EEEE??-????EEEEEESSHHHHHHHTTT 2PRV|A PF14568.1_SUKH_6_seed 86 171 !Q:13,20|31,31|33,33|36,42|49,77|81,81|95,97|101,109|115,115|124,128|132,132|135,135|138,139|142,149|160,160 Q:0,12|21,30|32,32|34,35|43,48|78,80|82,94|98,100|110,114|116,123|129,131|133,134|136,137|140,141|150,159|161,170 HHHHHHHHHHHTS-----???HHHHHHHHHH?S-EE-------ETTEEE??-------------------------??SSS?HHHHHHHHHHHHS???TTE---------EEEEE?SSEEEEEE-----TTS?BT-TB??EE--------EEETTTEEEE-EEESSHHHHH 2PRV|A PF14569.1_zf-UDP_seed 6 80 !Q:2,3|5,6|9,9|11,11|15,16|18,19|21,21|27,28|30,30|34,38|50,50|53,53|57,63|66,69|73,77|79,79 Q:0,1|4,4|7,8|10,10|12,14|17,17|20,20|22,26|29,29|31,33|39,49|51,52|54,56|64,65|70,72|78,78 SS??S??SS?B?SSS??B??B?SSSSB??S?SSS?????HHHHHHHHHTS?SS?TTT???????TT????TTS?????S? 1WEO|A PF14570.1_zf-RING_4_seed 58 63 !Q:0,0|4,5|7,10|16,17|20,20|24,27|37,41|43,44|46,51|54,54|58,59|61,61 Q:1,3|6,6|11,15|18,19|21,23|28,36|42,42|45,45|52,53|55,57|60,60|62,62 ?TTT??B?--?TTTTT??SS-TTS????HHHHHHHTT-----S--S-----?SB?TTT??B?S 1E4U|A PF14572.1_Pribosyl_synth_seed 11 202 !Q:26,26|32,93|97,98|111,111|113,113|128,129|139,141|153,154|163,164|171,171|178,179|194,196|199,199 Q:0,25|27,31|94,96|99,110|112,112|114,127|130,138|142,152|155,162|165,170|172,177|180,193|197,198|200,201 TGGGEEEEESSGGGHHHHHHHHHHTT?EEEEE???????-????-??????????-??------------?????????--?????????????EES??TTSEEEEEEEEE?S?HHHHHHHHHHHHTT??EEEEEEEEE???TTHHHHHHHSS??EEEEESSS??HHHHHT?TTEEEE??HHHHHHHHHHHHHT???TT?SS 1U9Z|A PF14573.1_PP-binding_2_seed 5 96 !Q:0,3|6,6|23,23|26,29|33,33|45,46|63,66|73,74|90,96 Q:4,5|7,22|24,25|30,32|34,44|47,62|67,72|75,89 ????TT?HHHHHHHHHHHHHTTB?TT????TTS?GGGSBBTTSSB??HHHHHHHHHHHHHHHT????HHHHTT??SHHHHHHHHHHHHHS??????- 3CE7|A PF14574.1_DUF4445_seed 215 691 !Q:0,0|8,8|21,23|25,27|36,36|42,42|54,54|56,60|62,68|80,80|94,100|103,132|144,144|154,156|160,167|172,179|181,182|184,194|196,201|208,209|211,217|220,220|228,231|236,236|245,245|249,250|253,257|259,265|268,270|272,274|279,279|288,290|292,293|295,295|297,297|305,306|318,319|331,335|339,340|343,349|351,351|354,354|359,380|382,429|432,432|450,450|453,454|456,456|459,461|463,475|480,480|482,485|487,487|490,490|496,498|501,507|509,509|511,515|517,517|519,525|528,528|537,537|558,558|561,562|566,567|576,576|591,593|595,595|602,602|604,604|617,644|658,660|662,663|665,666|668,670|674,676|680,680 Q:1,7|9,20|24,24|28,35|37,41|43,53|55,55|61,61|69,79|81,93|101,102|133,143|145,153|157,159|168,171|180,180|183,183|195,195|202,207|210,210|218,219|221,227|232,235|237,244|246,248|251,252|258,258|266,267|271,271|275,278|280,287|291,291|294,294|296,296|298,304|307,317|320,330|336,338|341,342|350,350|352,353|355,358|381,381|430,431|433,449|451,452|455,455|457,458|462,462|476,479|481,481|486,486|488,489|491,495|499,500|508,508|510,510|516,516|518,518|526,527|529,536|538,557|559,560|563,565|568,575|577,590|594,594|596,601|603,603|605,616|645,657|661,661|664,664|667,667|671,673|677,679|681,690 ?EEEEEEE?SSEEEEEEEETT---T-??EEEEEEEE?GGGGT?SSHHHHHHHHH-H?----T-------THHHHHHHHHH-HHHHHHHHHHHHH-------HT----------------------------??GGGEEEEEEEE?HHHHHHHHT???GGG--------SSTT--------T??S?----------S??--??EEHHHH--T?------SS?TTSEEEE????BTTB?HHHHHHHH-HHT--TT-----S----?--SS--?E---EEEE?SSEEEEEE---E-?S-S?EEEEEEE??GGGGTTTSSSB??SSTTEEEEEEE----?GGG--SS-------E-EE-EEGG----------------------G------------------------???--------------------?EE?HHHHHHHHHHHHHHTSB?TT??B?TT---T?------------SSSE-E-?-?T-TS?EEEEE-?-GG-------G-S-----S-S-------SS?EEEEHHHH-HHHHHHHHHHHHHHHHHHHH-TT??GGG??EEEEESSS?SEEEHHHHHHHTSS??-S?GGGEEE?S?HHHHHHHHHHHB----------------------------HHHHHHHHHHHHH?--E--E??T---TSS---SHH-HHHHHHTTSS 3ZYY|X PF14575.1_EphA2_TM_seed 64 164 !Q:0,149|152,152|159,159|161,162 Q:150,151|153,158|160,160|163,163 ----------------------------?-?-------------------------------?--???--?------??-????----??--?---??-----?--------------------??---------------?????????SS?SHHHHS?B??G 1JPA|A PF14578.1_GTP_EFTU_D4_seed 11 91 !Q:2,2|19,19|24,24|35,35|38,40|42,42|45,45|66,66|75,83|86,86 Q:0,1|3,18|20,23|25,34|36,37|41,41|43,44|46,65|67,74|84,85|87,90 SS?SEEEEEEEEEEETTEE-EEEE-EEEEEEEETT?EE---E?SS?EEEEEEEEETTEEESEEETT?EEEEEEES-??--????TT?EEEE 1SKQ|A PF14579.1_HHH_6_seed 364 188 !Q:1,2|5,7|11,11|13,13|15,15|17,18|21,65|68,75|77,83|86,86|94,95|105,105|110,111|114,118|120,120|126,127|132,140|143,145|148,148|162,162|164,164|167,171|173,174|176,181|184,185 Q:0,0|3,4|8,10|12,12|14,14|16,16|19,20|66,67|76,76|84,85|87,93|96,104|106,109|112,113|119,119|121,125|128,131|141,142|146,147|149,161|163,163|165,166|172,172|175,175|182,183|186,187 T??EE???TTT?B-S-S-?EE--------------------------------------------?TT--------S?------EE?BGGGSTT??HHHHHHHHH-HHTS--SS?---?S-SHHHH--HTTS--------?BT---TB?HHHHHHHHTTTTT-T-TT-----S--S---?--HH--HH 3E0D|A PF14580.1_LRR_9_seed 6 175 !Q:0,4|12,12|16,16|20,20|25,25|29,31|33,35|42,43|48,49|52,54|57,62|65,66|70,71|74,76|79,79|81,81|86,86|89,90|94,95|97,101|111,111|114,115|119,120|138,138|141,141|149,150|162,174 Q:5,11|13,15|17,19|21,24|26,28|32,32|36,41|44,47|50,51|55,56|63,64|67,69|72,73|77,78|80,80|82,85|87,88|91,93|96,96|102,110|112,113|116,118|121,137|139,140|142,148|151,161 ?????HHHHHTS?EEE?TTS?EEEE?TTS???S???GGGGTT??SEEE??SS???EE??????SS??EEE??SS???EE?S?HHHH?TT??EEE??S?????GGGGGGGGG?TT??EEE??SSGGGGSTTHHHHHHHH?TT?SEETTEE??HHHHHHHHHTT????????????? 2JE0|A PF14582.1_Metallophos_3_seed 6 276 !Q:0,9|16,17|20,20|35,37|45,49|64,69|95,95|102,103|107,108|123,123|129,129|146,146|153,154|157,159|163,163|181,183|192,193|195,195|200,200|206,208|210,210|221,222|228,233|236,237|240,241|252,253|275,275 Q:10,15|18,19|21,34|38,44|50,63|70,94|96,101|104,106|109,122|124,128|130,145|147,152|155,156|160,162|164,180|184,191|194,194|196,199|201,205|209,209|211,220|223,227|234,235|238,239|242,251|254,274 ?----?????EEEEEE??TT?GGGHHHHHHHHHHH-??SEEEEES?????HHHHHHHHHHHHTT???--?THHHHHHHHHHHHHHHHHHHHHHTT?SEEEEE??TTS??HHHHHHHHHHTTTT?TTEEE?SSEEEEETTTEEEEEE?SEEESS??BS---SSS?EEEHHHHHHHGGGGGGS???EEEEEESS??S?SSTT?BTTBS???S?HHHHHHHHHH??SEEEE-----?SS??EE--EEETTEEEEE??BGGGTEEEEEETTTTEEEEEE? 2YVT|A PF14583.1_Pectate_lyase22_seed 4 386 !Q:0,1|4,4|8,10|15,15|19,20|25,25|27,27|31,31|34,36|40,41|43,43|47,47|54,54|59,59|69,69|74,76|79,79|81,81|85,85|88,88|111,112|119,120|132,132|148,152|164,166|177,178|188,188|207,207|209,209|215,215|225,227|231,234|245,245|250,250|260,262|269,269|273,274|282,283|290,290|301,319|337,343|352,355|358,358|369,369|374,374|381,382 Q:2,3|5,7|11,14|16,18|21,24|26,26|28,30|32,33|37,39|42,42|44,46|48,53|55,58|60,68|70,73|77,78|80,80|82,84|86,87|89,110|113,118|121,131|133,147|153,163|167,176|179,187|189,206|208,208|210,214|216,224|228,230|235,244|246,249|251,259|263,268|270,272|275,281|284,289|291,300|320,336|344,351|356,357|359,368|370,373|375,380|383,385 ??TT?EEE???EEEE?TTT??EEEE?S?TTS?EE???TTS??B?TTS?EEEEEE?TTSS?EEEEEETTT?EEEE???SS?B?SSS?EE?TTSSEEEEEETTTEEEEEETTT??EEEEEE??TTEEEEEEEEE?TTSSEEEEEEEEGGG?????SHHHHHHHGGG???EEEEEEETTT??EEEEEEESS?EEEEEEETTEEEEEEEEE?S?TTTSS?SEEEEETTS???EES????TTEEEEEEEE?TTSS?EEEEEEETT???EEEEEE?TTT??EEEEEEE??EEEEEE?TTSSEEEEEE???????????????????EEEEEETTTTEEEEEEE???????BTTBSSTT????EE?TTSSEEEEEE?TTSS?EEEEEE??GGG 3PE7|A PF14586.1_MHC_I_2_seed 3 174 !Q:0,3|11,14|17,20|39,51|79,81|86,86|89,90|99,99|102,102|105,107|145,145|171,173 Q:4,10|15,16|21,38|52,78|82,85|87,88|91,98|100,101|103,104|108,144|146,170 ????EEEEEEE????SS????EEEEEEETTEEEEEEESS?????????????HHHHHHHHHHHHHHHHHHHHHHHHHTS???TTTT?SS??EEEEEEES?TT?SS???EEEEEETTTEEEEEETTTTEEEESBHHHHHHHHHHTT?HHHHHHHHTHHHHTHHHHHHHHHHS??? 1JSK|C PF14587.1_Glyco_hydr_30_2_seed 4 400 !Q:0,0|14,15|21,21|33,33|46,48|50,50|54,54|56,56|58,60|62,62|67,70|79,80|86,89|92,92|96,96|98,98|117,119|124,124|127,128|139,141|144,144|146,146|149,149|152,152|168,168|173,174|180,181|183,183|187,187|191,192|195,200|220,220|222,222|224,224|238,240|242,242|245,248|261,262|265,265|275,276|279,279|301,301|304,305|310,313|315,320|324,324|328,328|336,337|353,354|367,368|377,378|381,382|387,395|398,399 Q:1,13|16,20|22,32|34,45|49,49|51,53|55,55|57,57|61,61|63,66|71,78|81,85|90,91|93,95|97,97|99,116|120,123|125,126|129,138|142,143|145,145|147,148|150,151|153,167|169,172|175,179|182,182|184,186|188,190|193,194|201,219|221,221|223,223|225,237|241,241|243,244|249,260|263,264|266,274|277,278|280,300|302,303|306,309|314,314|321,323|325,327|329,335|338,352|355,366|369,376|379,380|383,386|396,397 ?EEEEEEEEEEEEE??EEEEE?TTTHHHHHHHS?HHHHHHHHHHHH???B?TTS?B?S???S?EEEE????TTTTTTSS??SSSSS????SB?TTS?B?TTSSHHHHHHHHHHHHTT???EEEE?SS??GGGSSSSSSS???SS-S?SS?TT?HHHHHHHHHHHHHHH-HHTT??EEEEE??S?TTS?GGG??SS??????HHHHHHHHHHHHHHHHHHT?S?E-EEEEEESSGGGGS???S?TT????HHHHHHSTTSTT??TT?TTEEEEEEE??TT?SSSHHHHHHHHHHHHHHHHTT-SS??EEEE????S???--?TTT?SSS?HHHHHHH--HHHHHHHHHHHHHTS??SEEEEEESEESS--SSSSEEEE??TT??SGGG---------GT?? 3CLW|A PF14588.1_YjgF_endoribonc_seed 2 148 !Q:8,16|21,21|33,34|36,37|44,45|48,48|54,54|83,84|94,94|96,96|99,101|122,123|130,130|133,133|147,147 Q:0,7|17,20|22,32|35,35|38,43|46,47|49,53|55,82|85,93|95,95|97,98|102,121|124,129|131,132|134,146 HHHHHHTT?????????SSSS?SEEEETTEEEE??B??EETTEE??BS?BTTTB?HHHHHHHHHHHHHHHHHHHHHHHSSGGG??EEEEEEEEE?B?TT???HHHHHHHHHHHHHHHHGGGG??EEEEEE?SS?GGGBSEEEEEEEE? 3D01|A PF14589.1_NrfD_2_seed 3 266 !Q:0,0|5,6|8,8|10,10|13,13|41,41|66,66|73,73|81,82|85,85|108,108|110,110|136,136|143,143|167,167|174,174|194,197|202,203|222,225|246,248|258,265 Q:1,4|7,7|9,9|11,12|14,40|42,65|67,72|74,80|83,84|86,107|109,109|111,135|137,142|144,166|168,173|175,193|198,201|204,221|226,245|249,257 ?EEES??S?S?SS?HHHHHHHHHHHHHHHHHHHHHHHHHHT?TTHHHHHHHHHHHHHHHHHHHHTT?TTTTTT?GGGGSSS??TT?HHHHHHHHHHHHHHHHHHHHTT?S?SSTTHHHHHHHHHHHHHHHHHHHHT?TTSTTS?TTHHHHHHHHHHHHHHHHHHHTT?SSSTTH-HHHHHHHHHHHHHHSGGGS?---HHHH--HHHHHHSSTTHHHHHHHH----GGGGSSTTTHHHHHHHHHHH---HHHHHHHHT?????--? 2VPX|C PF14590.1_DUF4447_seed 5 166 !Q:0,7|20,21|31,32|45,47|80,81|89,89|99,99|106,107|128,129|136,137|150,151|165,165 Q:8,19|22,30|33,44|48,79|82,88|90,98|100,105|108,127|130,135|138,149|152,164 ????????HHHHHHHHHHTT??HHHHHHHHT??HHHHHHHHTTSS???HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTS??SEEEEEE?SSHHHHHHH?GGGTTT??SHHHHHHHHHHHHHHHHHHH??EEEEEE??HHHHHHHHHHHT??SSHHHHHHHHHTT? 2OX6|A PF14591.1_AF0941-like_seed 6 151 !Q:0,2|14,24|28,28|35,35|38,46|54,55|73,73|107,125|136,143 Q:3,13|25,27|29,34|36,37|47,53|56,72|74,106|126,135|144,150 ???HHHHHHHHHHT-----------TSS?GGGHHH-HT--------?HHHHHHH--HHHHHHHHHHHHHTTSS?HHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHTT?????????----------HHHHHHHHHH--------HHHHHHT 1YOZ|A PF14592.1_Chondroitinas_B_seed 6 455 !Q:1,1|13,14|17,17|22,22|29,29|34,37|42,42|59,59|64,64|73,73|79,81|85,86|90,91|95,97|99,99|103,103|108,108|113,114|117,117|119,119|124,126|129,133|135,135|140,140|144,146|150,150|155,155|158,160|162,164|166,173|178,178|182,182|184,186|190,192|197,197|202,202|204,208|213,213|219,219|232,232|237,237|242,242|251,251|254,254|259,259|264,264|269,269|271,272|276,276|280,280|285,285|293,293|301,301|305,306|314,316|319,319|324,324|329,329|339,339|353,355|357,359|361,361|366,366|370,371|373,378|382,385|388,392|401,402|405,411|415,417|421,423|425,426|430,448|451,454 Q:0,0|2,12|15,16|18,21|23,28|30,33|38,41|43,58|60,63|65,72|74,78|82,84|87,89|92,94|98,98|100,102|104,107|109,112|115,116|118,118|120,123|127,128|134,134|136,139|141,143|147,149|151,154|156,157|161,161|165,165|174,177|179,181|183,183|187,189|193,196|198,201|203,203|209,212|214,218|220,231|233,236|238,241|243,250|252,253|255,258|260,263|265,268|270,270|273,275|277,279|281,284|286,292|294,300|302,304|307,313|317,318|320,323|325,328|330,338|340,352|356,356|360,360|362,365|367,369|372,372|379,381|386,387|393,400|403,404|412,414|418,420|424,424|427,429|449,450 E?SHHHHHHHHHH??TT?EEEE?SEEEET?EEEE????BTTB?EEEEESSTTSEEEEES?EEEE?SSSEEEES?EEEEE???TTS??TTS??SEE---E?SSS?EEES?EEES??SS?S?SEEE???TT?????S?EEES?EEE???SSS?SEEE?SS???S???S????????EEES?EEE-E???SSS???SEEE?SSTT?B--???EEES?EEEEE?SSSEEEEEESBT?EEES?EEES?SSEEEEEE?SS?EEES?EEEE?SSSS?B??EEE?SBS?EEES?EEEESSB?GGGTSEE-EEE??BSTTSTT???BS?EEES?EEES?SSEEEESST-THHHHHHHHHHHT???B???S?EEES?EEE??S-?????SEE?---TT?---?TTSSEEES?-EE-------ESS?-?SSS???B??GGG???-----????-?????-TT???? 1OFM|A PF14593.1_PH_3_seed 31 131 !Q:0,0|8,10|12,13|24,25|30,31|43,47|62,62|66,71|74,74|90,94|102,109|113,113|130,130 Q:1,7|11,11|14,23|26,29|32,42|48,61|63,65|72,73|75,89|95,101|110,112|114,129 ?TTGGGTT---T??EEEEEEEEEE--ETTE--EEEEEEEEETT-----TEEEEEETTTTEEE-EEE???---TT?EEEEEETTEEEEEET-----TEEEEEE?-------TTS?HHHHHHHHHHHHHHHH? 3TFM|A PF14595.1_Thioredoxin_9_seed 80 183 !Q:2,2|9,17|20,20|22,30|35,35|48,50|60,61|63,63|65,65|71,72|75,75|90,90|93,93|95,95|103,103|112,115|121,123|126,127|135,145|148,150|153,153|160,160|169,178 Q:0,1|3,8|18,19|21,21|31,34|36,47|51,59|62,62|64,64|66,70|73,74|76,89|91,92|94,94|96,102|104,111|116,120|124,125|128,134|146,147|151,152|154,159|161,168|179,182 SB?HHHHHH---------TS?H---------HHHH-HHHHHHHHHHHH???HHHHHHHHT??S?E-EEEEE??TT?HHHHHHHHHHHHHH-HH?T-TEEEEEE?HHHHHHHT----TTTTT--?SS??SSEEEEE?----------TT-??EE-EEEESS?HHHHHHHH----------HHHH 1DBY|A PF14597.1_Lactamase_B_5_seed 4 199 !Q:0,0|3,3|28,29|32,33|38,42|54,55|60,60|66,66|77,78|90,90|93,94|99,99|102,102|114,114|134,134|145,145|148,149|153,153|155,155|169,169|172,173|181,182|184,184|186,186 Q:1,2|4,27|30,31|34,37|43,53|56,59|61,65|67,76|79,89|91,92|95,98|100,101|103,113|115,133|135,144|146,147|150,152|154,154|156,168|170,171|174,180|183,183|185,185|187,198 ?EE?SSTTEEEEEEEETTTTEEEEEEEE??TT??EEES?????HHHHHHHHHTT??SEEE?SSGGG?TTHHHHHHHS??EEEEEGGGTTS?SS??SEEE?TT?BSSTTEEEEEE?SSSSTTEEEEEETTTEEEE?SSEEBSSTTS?EE??GGG?S?HHHHHHHHHHHHT?TT??EEEESBB??B?S?HHHHHHHHHHHH 2P97|A PF14598.1_PAS_11_seed 22 134 !Q:0,1|8,8|11,12|18,18|25,27|29,29|31,31|34,34|46,46|51,52|64,73|77,77|79,80|82,86|91,91|95,97|109,119|129,133 Q:2,7|9,10|13,17|19,24|28,28|30,30|32,33|35,45|47,50|53,63|74,76|78,78|81,81|87,90|92,94|98,108|120,128 ??EEEEEE?TT??EEEEE?HHHHTT?-?S?H-HH-HHHHHHHHHTS?BTTB??HHHHHHHHHHH----------HSE-E--E???--EEEE?TTS--?EEEEEEEEEEE?--????????EEEEEEEEE????? 3GDI|A PF14599.1_zinc_ribbon_6_seed 75 70 !Q:0,29|39,41|47,48|51,54|57,58|60,62|64,66 Q:30,38|42,46|49,50|55,56|59,59|63,63|67,69 ???????????????????---????????EEEEEESSS??-EEEEE??TT????TT--T---S???EEE 2K2D|A PF14600.1_CBM_5_12_2_seed 5 62 !Q:0,1|7,7|11,12|21,23|29,29|45,45|47,47|60,61 Q:2,6|8,10|13,20|24,28|30,44|46,46|48,59 ??SSSSS?BTT??SBSSSSSS???BEEBT?EEEETTEEEEESSEE?S?TTSSTTEEEEEE?? 1AIW|A PF14601.1_TFX_C_seed 28 84 !Q:2,2|11,13|19,20|40,40|42,45|57,57|61,65|69,69 Q:0,1|3,10|14,18|21,39|41,41|46,56|58,60|66,68|70,83 SS?HHHHHHHH???EEEEE??GGGHHHHHHHHHHHHHHHS?S????HHHHHHHHHHH?SSS?????SSS?EEEEESSSSSEEEE 1NR3|A PF14602.1_Hexapep_2_seed 86 41 !Q:1,1|4,4|7,7|10,10|13,14|16,17|19,23|25,25|27,27|30,30|33,33|36,36|39,39 Q:0,0|2,3|5,6|8,9|11,12|15,15|18,18|24,24|26,26|28,29|31,32|34,35|37,38|40,40 B?EE?TT?EE?TT-?E--E--?--S?B?SS?EE?TT?EE?T 3FS8|A PF14603.1_hSH3_seed 3 89 !Q:5,7|9,12|15,16|18,19|23,23|26,28|32,35|38,38|40,40|69,88 Q:0,4|8,8|13,14|17,17|20,22|24,25|29,31|36,37|39,39|41,68 HHHHT???S????SS??B??TTS?SS???TTB????TT?B?EEEEESSSSEEEEEETTTEEEEEEGGGS????????------------ 2GTJ|A PF14604.1_SH3_9_seed 37 83 !Q:3,7|10,11|13,13|15,16|18,23|26,26|31,35|37,45|47,49|53,53|56,59|61,64|66,67|70,72|74,75 Q:0,2|8,9|12,12|14,14|17,17|24,25|27,30|36,36|46,46|50,52|54,55|60,60|65,65|68,69|73,73|76,82 ESS???-?SS--T-T--S--????TT?EEEE--?--B?-----?--S---SSE-EB-?--B----S--SS--?B??EETTSEE 1MUZ|A PF14605.1_Nup35_RRM_2_seed 21 84 !Q:7,11|16,19|25,29|33,33|35,35|38,38|42,44|48,63 Q:0,6|12,15|20,24|30,32|34,34|36,37|39,41|45,47|64,83 GGEEEEE???--GGGH----HHHHH-----HHH-T-TS?EEE---EEE?---------------SSSSEEEEEESSHHHHHHHH 1WWH|A PF14606.1_Lipase_GDSL_3_seed 20 199 !Q:2,3|9,9|17,17|41,41|45,45|47,48|59,62|69,70|73,82|84,88|107,107|111,111|116,121|125,125|128,128|149,149|155,155|162,165|167,167|169,169|173,173|182,182 Q:0,1|4,8|10,16|18,40|42,44|46,46|49,58|63,68|71,72|83,83|89,106|108,110|112,115|122,124|126,127|129,148|150,154|156,161|166,166|168,168|170,172|174,181|183,198 EE--EEEEE?HHHHTTT?SSGGGSHHHHHHHHHSEEEEEEE?TTT?S??HHHHHHHHTS-??-SEEEEE??SS----------S----?HHHHHHHHHHHHHHHHHH?SSS?EEEE????-?GGG-GT?HHHHHHHHHHHHHHHHHHHH-HHHTT?SSEEEE????T-T?SSS?SBSSSSSB?HHHHHHHHHHHHHHHH 3SKV|A PF14607.1_GxDLY_seed 44 169 !Q:0,1|11,13|18,18|20,20|22,23|25,26|30,30|33,33|40,42|44,44|54,54|57,57|64,65|67,67|74,81|85,85|91,91|99,100|110,110|112,114|117,120|122,122|129,132|134,139|141,141|148,149|153,155|166,166 Q:2,10|14,17|19,19|21,21|24,24|27,29|31,32|34,39|43,43|45,53|55,56|58,63|66,66|68,73|82,84|86,90|92,98|101,109|111,111|115,116|121,121|123,128|133,133|140,140|142,147|150,152|156,165|167,168 ??EEEEEGGGS---EEES?S?S-?S--STT?SS?TTTTTT---S?HHHHHHTTS?TT?EEEEEE??S?EEEEEE????-???TTS?HHHHH?EEEEEEE--TTEEEEEEE-E???SS----E-EEEEEE????S------S?EEEEEE??SSS???EEEEEEETTS?EE 4LHS|A PF14608.1_zf-CCCH_2_seed 44 21 !Q:1,1|3,3|8,11|13,13|15,15|19,20 Q:0,0|2,2|4,7|12,12|14,14|16,18 B?S-SGGG-???T-T?SSB?? 3ZJ2|A PF14614.1_DUF4450_seed 8 244 !Q:0,2|20,21|23,23|25,26|32,32|37,57|59,59|72,74|76,76|78,78|87,97|100,100|103,119|134,134|136,136|140,145|150,156|161,161|163,164|166,166|171,171|175,175|184,188|191,191|199,200|204,212|221,226|228,229|232,232|241,243 Q:3,19|22,22|24,24|27,31|33,36|58,58|60,71|75,75|77,77|79,86|98,99|101,102|120,133|135,135|137,139|146,149|157,160|162,162|165,165|167,170|172,174|176,183|189,190|192,198|201,203|213,220|227,227|230,231|233,240 ???SSSEEEEEEEETTEEEE??T-T??BTTEE-EEEE---------------------E?SSSSEEEEEEEE???S-S?SEEEEEEE???--------SS?SE-----------------EEEEEETTEEEEEE-E-ETT------EEEE-------EEEE?S?-S?EEEE?GGG?SSHHHHHT?????SS?EEEEEEE??TTE---------EEEEEEEE-?????S??TT-THHHHHHH??? 4E0E|A PF14622.1_Ribonucleas_3_3_seed 70 259 !Q:0,0|10,10|15,16|19,22|24,28|30,33|35,51|63,65|68,69|71,74|76,80|82,82|85,94|96,96|98,98|100,100|103,114|116,116|118,118|120,124|126,126|128,128|130,138|140,140|145,145|147,147|149,151|155,155|158,165|168,168|173,173|177,187|192,192|194,200|206,206|212,214|217,218|236,236|245,247|249,249|251,253 Q:1,9|11,14|17,18|23,23|29,29|34,34|52,62|66,67|70,70|75,75|81,81|83,84|95,95|97,97|99,99|101,102|115,115|117,117|119,119|125,125|127,127|129,129|139,139|141,144|146,146|148,148|152,154|156,157|166,167|169,172|174,176|188,191|193,193|201,205|207,211|215,216|219,235|237,244|248,248|250,250|254,258 ?HHHHHHHTB?HHHH--HH----T-----T----S--?----?----?----THHHHHHHHHH---HH--H----H-----H-HH----------H-H-H-HH-----------?T-T-S--?--H-H-H---------H-HHHH-H-H---HHS-HH--------HH-HHHH-HHH?----------SGGG?B?-----?HHHHH-TTGGG?--HH--HHHHHHHHHHHHHHHHH?HHHHHHHH---H-H---HTHHH 1RC5|A PF14631.1_FancD2_seed 4 1448 !Q:0,51|64,66|70,71|76,76|93,93|122,122|124,139|169,172|175,177|189,189|191,192|210,210|226,226|244,244|259,261|280,280|295,295|313,344|364,364|384,385|399,399|401,401|419,419|421,421|474,474|492,493|511,511|532,533|552,552|555,557|573,573|595,612|651,655|677,679|682,682|685,686|689,690|694,696|700,700|705,705|708,708|717,717|720,736|758,759|768,769|773,775|777,777|784,785|813,815|844,844|846,849|852,852|856,930|939,942|952,974|994,1015|1021,1021|1050,1064|1088,1088|1108,1108|1112,1113|1115,1116|1119,1120|1139,1140|1159,1165|1181,1192|1212,1212|1231,1238|1241,1243|1266,1272|1303,1304|1337,1337|1361,1361|1393,1393|1396,1397|1409,1447 Q:52,63|67,69|72,75|77,92|94,121|123,123|140,168|173,174|178,188|190,190|193,209|211,225|227,243|245,258|262,279|281,294|296,312|345,363|365,383|386,398|400,400|402,418|420,420|422,473|475,491|494,510|512,531|534,551|553,554|558,572|574,594|613,650|656,676|680,681|683,684|687,688|691,693|697,699|701,704|706,707|709,716|718,719|737,757|760,767|770,772|776,776|778,783|786,812|816,843|845,845|850,851|853,855|931,938|943,951|975,993|1016,1020|1022,1049|1065,1087|1089,1107|1109,1111|1114,1114|1117,1118|1121,1138|1141,1158|1166,1180|1193,1211|1213,1230|1239,1240|1244,1265|1273,1302|1305,1336|1338,1360|1362,1392|1394,1395|1398,1408 ----------------------------------????????------????HHHHHHHHTTEE???TTS??EESS?TTHHHHHHHHHHHHSS?HHHHHHHHHHHHHHHTTSHHHHHHHSSB?B???????-????????BHHHHHHHSTTTHHHHHHHHHHHHHHHHS????TT???HHHHHHGGGTT?S??SSHHHHHHHHHHHHHHS?TTTHHHHHHTHHHHS?GGGHHHHHHHHHHHHHH?STTHHHHHHHHHHS???HHHHHHHHHHHHHSTTSS?TTHHHHHHHHHHHS?SSTTHHHHHHHHHHHHH???????????????????????-????????HHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHGGGSTT??THHHHHHHHHHHH?H-HHHHHHHHHHHHHHTTT?S?HHHHHHHHHHHHHHHTTSHHHHHHHHHHHHTSSSHHHHHHHHHHHHHHHHSS?HHHHHHHHHHHHHHHHH??HHHHHHHHHHHHHHHHH?HHHHHHTHHHHHGGGGGGGG??HHHHHHHHHHHHHHHHHH?SS???HHHHHHHHHHHHHHT?SSHHHHHHHHHHHHHHHHHTT??????????????????HHHHHHHHHHHHHHHHHSSSHHHHHHHHHHHHHHHHHS?--??HHHHHHHHHHHHHHHHHHHEE???SS?SS??SS??EEE???SSS?SSSS?EE?HHHHHHHH-HH?????????????????TTSHHHHHHHHHHHHHHHHTT??TTTGGGSS??EEE???S?SSSSTT??THHHHHHHHHHHHHHHHHHHHHHHHTT???HHHHHHHHHHHHHHHHHHHHHHHHHTTS?S????SS?STT???????-------------------------------------------------------------?-?????HHHHTTTS????GGGGGGGGS???????????????????????HHHHHHHHHHHHHHHHHHH??????????????????????TTTTS?HHHHHHHHHHHHHHHHHHHHHHHHHHHH???????????????HHHHHHHHHHHHHHHHHHHHHHT?TTTTSSTTHHHHHHHHHTT?TTS??S?-SS??HHHHHHHHHHHHHGGGGG??SHHHHHHHHHHHHHHHTT-??????HHHHHHHHHHHHTTS???--???????HHHHHHHHHHHHHHHHHSS?HHHHHHHHHHTTTHHHHS????????SS???SHHHHHHHHHHHHHHHHHHHTT???????HHHHHHHHHHHHHHHHHHHHHHHHHHHTTT??SHHHHHHHHHHHHHHHHHHHTHHHHHHHHTTT?HHHHHHHHHHHHHHHHHHHHHHS?SGGGSSGGGGTTHHHHHHHHHHHHHHHHHHH?SS??HHHHHHHHHTS???????????????---??????-?????--------- 3S4W|B PF14633.1_SH2_2_seed 4 229 !Q:0,27|32,35|41,41|43,44|56,56|59,59|65,65|68,68|93,93|99,100|107,112|144,148|150,150|169,169|176,176|194,195|203,203 Q:28,31|36,40|42,42|45,55|57,58|60,64|66,67|69,92|94,98|101,106|113,143|149,149|151,168|170,175|177,193|196,202|204,228 ----------------------------TTTS????SSTTB?S??HHHHHHHHTTS?TT?EEEEE?SB?SSEEEEEEEEETTEEEEEEEEEES?SSTTS??SEEEET------TEEESSHHHHHHHTHHHHHHHHHHHHTSTTB??---S?HHHHHHHHHHHHTTSTTS?EEEEEE?SSSTTEEEEEEESSTTS??EEEEEEE?SSSEEETTEEESSHHHHHHHHHHHT 3PSK|A PF14634.1_zf-RING_5_seed 118 84 !Q:1,1|3,4|7,7|9,25|28,32|34,36|39,39|41,43|45,45|47,48|56,72|76,76|79,80|82,83 Q:0,0|2,2|5,6|8,8|26,27|33,33|37,38|40,40|44,44|46,46|49,55|73,75|77,78|81,81 S?S--SS?S??---------------SS?----B???SS-S??-B?T--TTGGGGT-----------------TTB?SS--S?? 1JM7|B PF14635.1_HHH_7_seed 4 104 !Q:6,8|15,15|35,35|44,44|57,58|73,73|75,78|87,87|89,89|102,103 Q:0,5|9,14|16,34|36,43|45,56|59,72|74,74|79,86|88,88|90,101 HHHHTS???TTGGGS?HHHHHHHHHHHHHHHHHHH?EEHHHHTT?HHHHTTGGGSTT??HHHHHHHHHHHHHH?S????TTHHHHTT?S?HHHHHHHGGGEE?? 3PSI|A PF14639.1_YqgF_seed 4 160 !Q:1,5|11,11|14,15|20,20|27,27|31,31|39,47|49,49|52,52|55,55|71,72|78,79|100,100|102,102|106,106|108,109|113,115|131,131|134,135|150,150|159,159 Q:0,0|6,10|12,13|16,19|21,26|28,30|32,38|48,48|50,51|53,54|56,70|73,77|80,99|101,101|103,105|107,107|110,112|116,130|132,133|136,149|151,158 S?????EEEEE?TT??TTTT?EEEEEE?TTS?EEEEEEE--------?S?TT?SS?SHHHHHHHHHHHHHH??SEEEE??SSTHHHHHHHHHHHHHHHTT?B?SSS?B??EEE???TTHHHHHTSHHHHHH?TT??HHHHHHHHHHHHHH?HHHHHHHS? 3PSI|A PF14641.1_HTH_44_seed 4 148 !Q:0,0|5,7|17,18|29,31|34,45|50,56|70,72|80,80|85,86|88,88|94,96|98,99|131,144 Q:1,4|8,16|19,28|32,33|46,49|57,69|73,79|81,84|87,87|89,93|97,97|100,130|145,147 ?TTSS???HHHHHHHHH--HHHHHHHHHH???SS???---------HHHH-------HHHHHHHHHHHTS???HHHHHHH?GGGS--B?SSSSS?--B??HHHHHHHHHHHHHHHHHHHHHHHHHHHHHTT??----------??HHH 3PSI|A PF14651.1_Lipocalin_7_seed 3 128 !Q:0,2|22,24|35,36|42,42|48,49|61,62|84,85|127,127 Q:3,21|25,34|37,41|43,47|50,60|63,83|86,126 -??EEEEEEEEESSHHHHHHHH???HHHHHHHHHS??EEEEE?BTTEE??EEEETTTEEEE??EETTSEEEEEETTTEEEEEEE??BTTBEEEEETTEEEEEEEETTEEEEEEEETTEEEEEEEEEE? 2A0A|A PF14659.1_Phage_int_SAM_3_seed 221 70 !Q:6,6|10,11|15,15|19,19|23,24|37,37|43,45|48,48|53,56|63,63 Q:0,5|7,9|12,14|16,18|20,22|25,36|38,42|46,47|49,52|57,62|64,69 BHHHHH-HHH--HHH-HTG-GGS?-HHHHHHHHHHHH-HHHHH?--SS?BGGG??--HHHHHH-HHHHHH 2KKP|A PF14660.1_DUF4458_seed 25 205 !Q:8,58|62,62|68,69|72,72|79,83|85,85|89,108|110,112|115,135|141,147|149,149|165,171|174,178|180,182|186,186|189,191|193,194|199,199|202,202 Q:0,7|59,61|63,67|70,71|73,78|84,84|86,88|109,109|113,114|136,140|148,148|150,164|172,173|179,179|183,185|187,188|192,192|195,198|200,201|203,204 EEEEEEEE???-------??-????-????------------?--??--???--?????EEE-EEEES--SS?EEEEEE-----E-EEE???----------------?S---SE---------------------EEEEE-----??E-EEESEEEEEEEEEEE------?TT?---?E---EEE-EE??-S??EEEE?TT?EE 4ECN|A PF14667.1_Polysacc_synt_C_seed 347 263 !Q:12,12|16,16|18,18|20,20|22,22|24,27|29,29|31,31|34,34|38,38|47,49|59,59|66,67|70,76|78,79|81,83|85,93|106,106|110,110|115,115|117,117|123,124|126,128|130,130|132,138|140,141|143,144|146,146|148,148|150,150|153,155|159,162|164,164|175,178|181,181|187,187|191,214|217,219|226,229|235,237|241,241|246,248|257,260 Q:0,11|13,15|17,17|19,19|21,21|23,23|28,28|30,30|32,33|35,37|39,46|50,58|60,65|68,69|77,77|80,80|84,84|94,105|107,109|111,114|116,116|118,122|125,125|129,129|131,131|139,139|142,142|145,145|147,147|149,149|151,152|156,158|163,163|165,174|179,180|182,186|188,190|215,216|220,225|230,234|238,240|242,245|249,256|261,262 HHHHHHTTHHHH-HHH-H-H-H-H----H-H-HH-HTT?HHHHHHHH---HHHHHHHHH-HHHHHH--TT-------S??T---H---------HHHHHHHHHHHH-HHH-HHHH-H-HHHTT??S---T-T-???--?H--H--H-H-H-HH---HHH----H-HHHHHHHHHH----HH-HHHHH-HHH------------------------HH---HHHHHH----HHHHH---HHH-HHHH---HHTTHHHH----HH 3WBN|A PF14670.1_FXa_inhibition_seed 204 108 !Q:4,5|7,8|10,11|13,17|19,22|24,25|27,28|30,30|32,43|45,45|47,62|64,67|69,69|71,74|76,77|79,81|83,83|85,94|96,96|98,99|102,106 Q:0,3|6,6|9,9|12,12|18,18|23,23|26,26|29,29|31,31|44,44|46,46|63,63|68,68|70,70|75,75|78,78|82,82|84,84|95,95|97,97|100,101|107,107 GGTG--G--G--G---?-S----S--E--E-E--?-?-------S-S-----------?--?-E----E-E??--T--T-?-E-E-?--------T-T--SS---?-E 3GCW|E PF14671.1_DSPn_seed 42 169 !Q:0,2|12,12|15,27|34,35|38,39|42,45|47,50|53,58|75,77|90,91|93,93|95,98|117,119|128,128|132,143|145,146|152,152|154,155|157,157 Q:3,11|13,14|28,33|36,37|40,41|46,46|51,52|59,74|78,89|92,92|94,94|99,116|120,127|129,131|144,144|147,151|153,153|156,156|158,168 ---SSSSEEEEE?SS-----?????---TTEEEE??TT--TS????S----SS??????HHHHHHHHHHHHHHHH?--TTSTTSEEEEEE?-S?H----HHHHHHHHHHHHHHHHTS???HHHHHHHH-TTT?----?--????B??SSSSS?S??B?HHHHHHHHHHH 1OHD|A PF14674.1_FANCI_S1-cap_seed 5 53 !Q:0,0|11,11|24,24|26,26|38,38 Q:1,10|12,23|25,25|27,37|39,52 ?HHHHHHHHHH?TTHHHHHHHHHH?S?SHHHHHHHHHH?HHHHHTHHHHHHTT 3S51|A PF14675.1_FANCI_S1_seed 16 284 !Q:20,22|40,41|57,80|83,85|87,87|101,106|110,111|113,114|119,122|138,140|155,157|175,175|177,177|196,196|201,202|222,261 Q:0,19|23,39|42,56|81,82|86,86|88,100|107,109|112,112|115,118|123,137|141,154|158,174|176,176|178,195|197,200|203,221|262,283 HHHHHHHHHHHHHHHHHHHS???HHHHHHHHHHHHHHGGG??HHHHHHHHHHHHHHH------------------------HS???S?STTTTHHHHHHHH------HHT??S??SSSS????HHHHHHHHHHHHHHS???TTTHHHHHHHGGGS???HHHHHHHHHHHHHHHTT-S?GGGHHHHHHHHHHHHTTS?HHHH--HHHHHHHHHHHHHHHHHHH??????----??--?-----------------------??SHHHHHHHHHHHHHHHHHHHHH 3S51|A PF14676.1_FANCI_S2_seed 25 209 !Q:15,24|28,29|33,44|54,60|73,73|91,92|95,96|101,119|129,129|135,135|137,137|142,146|153,153|157,157|175,176|193,193 Q:0,14|25,27|30,32|45,53|61,72|74,90|93,94|97,100|120,128|130,134|136,136|138,141|147,152|154,156|158,174|177,192|194,208 TTHHHHHHHHHHHHH----------HHS??TTS????????????THHHHHHHH-------HHHHHHHHHHHH?GGGHHHHHHHHHHHHHH??SS??HHHH-------------------HHHHHHHHH?HHHHS-S?HHHH-----GGGGGT-TTS?HHHHHHHHHHHHHHHTT?-HHHHHHHHHHHHHHTT?SSHHHHHHHHHHHHH 3S51|A PF14677.1_FANCI_S3_seed 13 241 !Q:0,0|2,2|16,17|20,20|22,22|33,33|37,37|56,57|64,64|84,102|134,153|176,176|178,179|182,183|202,202|205,205|210,210|223,225|227,227|236,236 Q:1,1|3,15|18,19|21,21|23,32|34,36|38,55|58,63|65,83|103,133|154,175|177,177|180,181|184,201|203,204|206,209|211,222|226,226|228,235|237,240 ?S?HHHHHHHHHHHTT??SS-S?HHHHHHHHTT?HHH-HHHHHHHHHHHHHHHHSS??SSTTSS?HHHHHHHHHHHHHHHHHHH???????-???????????HHHHHHHHHHHHHHHHHHTSGGGHHHHHHHT?????????-???-------HHHHHHHHHHHHHHHHHHHHHH-S??SS??SHHHHHHHHHHHHHTTSS?SS?SHHH-HHHHHHHHHHHS???S?HHHHHHHH-HHHH 3S51|A PF14678.1_FANCI_S4_seed 19 311 !Q:15,42|58,58|77,101|127,129|161,170|177,177|181,193|209,214|220,259|283,286|292,310 Q:0,14|43,57|59,76|102,126|130,160|171,176|178,180|194,208|215,219|260,282|287,291 HHHHHHHHHHHHHHH????--?????-----????--??????HHHHTTTHHHHHHHH-HHHHHHHHHHHHHHHHTT???????---???????????????HHHHHHHHHHHHHHHHHHHHHHHHS???TTTHHHHHHHHHHHHHHHHHHHHHHHHHHTS????----??HHHHHH-HTT-------------HHHHTHHHHHHHHHH------HHHHH?????????-----?--------?????????????????HHHHHHHHHHHHHHHHHHHHHSS?--?HHHHH??????????????????? 3S51|A PF14679.1_FANCI_HD1_seed 19 88 !Q:10,11|21,22|63,63|71,75 Q:0,9|12,20|23,62|64,70|76,87 HHHHHHHHHH??SSTHHHHHH??HHHHHHHHHHTTSGGGHHHHHHHHHHHHHHHHHHHHHHTT?HHHHHHS?????HHHHHHHHHHHT 3S51|A PF14680.1_FANCI_HD2_seed 16 295 !Q:0,19|25,25|29,29|32,37|55,55|73,73|93,102|105,106|108,109|111,112|123,125|129,129|131,131|150,162|167,168|174,175|187,235|263,265|268,268|273,275|292,295 Q:20,24|26,28|30,31|38,54|56,72|74,92|103,104|107,107|110,110|113,122|126,128|130,130|132,149|163,166|169,173|176,186|236,262|266,267|269,272|276,291 ??-----??-???-??????EESSS?SSS?SS---??-TTHHHHHHHHHHGGGGS?HHHHHHHHHHHHHHHHH?GGGHHHHHHHHHHHHHHHB??--------SS??S??B??STTEEEETTE---EEE?S?HHHHHHHHHHHHHHHHHT??????-??????HHHH--HHHHH--HHHHHHHHHHH????--??????--------------------------???????-???HHHHHHHHHHHHHHHHHHHHHHHHHHH--?SS?HHHH---HHHHHHHHHHHHHHHH???- 3S51|A PF14681.1_UPRTase_seed 113 372 !Q:1,4|16,16|19,21|43,43|45,46|48,48|50,54|56,57|61,66|69,74|76,76|79,82|84,84|86,96|98,107|119,150|160,160|164,167|176,177|179,180|183,204|207,213|219,220|224,231|236,253|258,258|260,262|267,267|278,278|282,284|286,287|298,303|305,309|312,315|318,323|330,330|332,333|335,336|338,338|345,345|349,352|356,356|360,361|363,363|371,371 Q:0,0|5,15|17,18|22,42|44,44|47,47|49,49|55,55|58,60|67,68|75,75|77,78|83,83|85,85|97,97|108,118|151,159|161,163|168,175|178,178|181,182|205,206|214,218|221,223|232,235|254,257|259,259|263,266|268,277|279,281|285,285|288,297|304,304|310,311|316,317|324,329|331,331|334,334|337,337|339,344|346,348|353,355|357,359|362,362|364,370 E????HHHHHHHHHHH?TT?-?HHHHHHHHHHHHHHHHHHHHT-T--S?B-?--?E--EEE-----?TT------S?EE----E-E----?-?----B-??------?EEEEEEETGGG--------------------------------GGHHHHHHH-STT-?-?EEEEEEEE-?T--TT------------------??--EE-------EEEEE??TTG--------GGSE------------------EEEE?S---EESS?HHHHHHHHHH-HHH---T??GGGEEEEEEE------E----?HH----HH------HHHHHH?T--T-?E-EEEEEE?SEE--?-TTS?EES??S?HHHHHHT? 1O5O|A PF14682.1_SPOB_ab_seed 12 125 !Q:0,0|14,15|27,29|53,53|57,58|67,68|71,76|88,88|91,92|99,99|103,103|105,105|108,108|118,118 Q:1,13|16,26|30,52|54,56|59,66|69,70|77,87|89,90|93,98|100,102|104,104|106,107|109,117|119,124 ?HHHHHHHHHGGGS??SSEEEEEEESS???GGGGHHHHHHHHHHHHHHHTTTB?SSS??EEEEEEES??SS------SSEEEEEEEES?BS-?GGGGHH-HHS-S?BT-TBEEEEEEE?SSEEEE 1F51|A PF14683.1_CBM-like_seed 56 234 !Q:7,7|12,12|20,34|40,42|45,46|50,55|63,64|78,86|94,94|98,99|101,104|116,123|126,126|135,137|140,158|160,161|166,168|170,172|179,179|184,184|186,187|190,192|201,211|213,218 Q:0,6|8,11|13,19|35,39|43,44|47,49|56,62|65,77|87,93|95,97|100,100|105,115|124,125|127,134|138,139|159,159|162,165|169,169|173,178|180,183|185,185|188,189|193,200|212,212|219,233 SEEEEES?SSSS?TTSBTHH---------------HHTTS?--TT?-TTS??????EEETTTS-?GGGSBSEEETTTT-------??EEEEEEE?GGG-?S---?EEEEEEEEEEE--------TT?EEEEEETT---EE??------???--??????S??TTTT???S???EEEEEE?TTTS?S--EE---EEEEEEEE?----------S?-??--SGGGSSEEEEEEEEE 3NJV|A PF14684.1_Tricorn_C1_seed 129 81 !Q:18,20|22,22|24,28|30,30|35,35|37,38|53,54|71,72|74,76|79,80 Q:0,17|21,21|23,23|29,29|31,34|36,36|39,52|55,70|73,73|77,78 HHHHHHHHHHHHHHHHHH--?S?H-----H-HHHH-H--HHHHHHHHHTTGGG??SHHHHHHHHHHHHHTT??S???EE?? 1K32|A PF14685.1_Tricorn_PDZ_seed 47 100 !Q:0,0|2,2|9,9|11,12|14,15|18,19|26,26|29,29|35,35|37,37|44,47|50,50|60,60|65,65|76,77|86,86|88,88|91,93 Q:1,1|3,8|10,10|13,13|16,17|20,25|27,28|30,34|36,36|38,43|48,49|51,59|61,64|66,75|78,85|87,87|89,90|94,99 ?B?SEEEEE-E--T--TE--EEEEEE?BS?TTSTT?B?GGGGGT???-TT?EEEEETTEE?BTTB?HHHHHHTTTT--SEEEEEEE?S-SS--?EEEEEE 1K32|A PF14686.1_fn3_3_seed 51 117 !Q:1,1|10,12|15,20|24,24|26,27|33,46|49,49|55,57|64,66|68,68|72,72|80,88|95,97|104,104|107,107|111,112|115,116 Q:0,0|2,9|13,14|21,23|25,25|28,32|47,48|50,54|58,63|67,67|69,71|73,79|89,94|98,103|105,106|108,110|113,114 G?BEEEEEEE---SS?-----TTS?E--EEEEE-------------?SS?EEEEE?-?TTSEEE???B?SEE-EEEEEEE---------TTEEEE---EEEEEE?TT?EEE??EE?? 3NJV|A PF14689.1_SPOB_a_seed 56 65 !Q:0,4|16,16|38,38|57,57|61,61 Q:5,15|17,37|39,56|58,60|62,64 ?????HHHHHHHHHHH-HHHHHHHHHHHHHHHHHHHTT?HHHHHHHHHHHHHHHHHH-HHH-TTS 1F51|A PF14691.1_Fer4_20_seed 327 168 !Q:0,10|13,15|17,17|27,38|40,40|42,42|44,45|48,48|50,54|59,61|73,79|91,91|93,94|102,103|112,117|120,127|129,133|135,135|139,143|145,146|162,165|167,167 Q:11,12|16,16|18,26|39,39|41,41|43,43|46,47|49,49|55,58|62,72|80,90|92,92|95,101|104,111|118,119|128,128|134,134|136,138|144,144|147,161|166,166 --??-?-????SS???T-THHHHHHHS??-----?----S-S?H--HH-H-----TSTT???HHHHHHHHHHT?------HHHHHHHHHHH?S?-HHHHHHH??GGGSGGGG-----?GG--------G-----G-SSS?----S??HHHHHHHHHHHHHHH----T? 1H7W|A PF14693.1_Ribosomal_TL5_C_seed 195 135 !Q:1,2|8,9|12,18|24,24|26,29|32,33|35,35|42,44|48,53|56,56|59,62|64,64|67,69|72,72|74,85|87,88|90,103|105,113|115,115|117,126|129,132|134,134 Q:0,0|3,7|10,11|19,23|25,25|30,31|34,34|36,41|45,47|54,55|57,58|63,63|65,66|70,71|73,73|86,86|89,89|104,104|114,114|116,116|127,128|133,133 S??EEEEE??EE?--?---SSTTT-T-?-?EE??S?SEEEEE??-STT??????EE?TT?-?-S-SS???TT?S--?--?--?---T--T--???-?-------S-----?---S?S------????EE????S? 2ZJQ|S PF14696.1_Glyoxalase_5_seed 17 155 !Q:0,2|5,5|16,16|19,20|22,23|35,35|60,61|86,87|100,101|103,109|112,112|114,116|120,120|124,124|130,132|136,147 Q:3,4|6,15|17,18|21,21|24,34|36,59|62,85|88,99|102,102|110,111|113,113|117,119|121,123|125,129|133,135|148,154 ???TT?EEEEEEEEEE?SS--T--TSSHHHHHHTT?EEEEEESSSSEEEEEETTEEEEEE??SSSHHHHHHHHHSSEEEEEEEEES?-HHHHHHHHHHTT??B????-??TT?B???EEE?GGG?EEEEE???SSS?----------?HHHHHEE 2R5V|A PF14697.1_Fer4_21_seed 63 104 !Q:3,3|7,11|22,24|26,32|34,35|37,42|45,46|48,63|65,70|72,72|74,78|80,80|82,87|93,93|96,97 Q:0,2|4,6|12,21|25,25|33,33|36,36|43,44|47,47|64,64|71,71|73,73|79,79|81,81|88,92|94,95|98,103 EEE?TTT?????HHHHHHHHHS???E-------E--E---?--TT--T-----?--?-------E------E-E---?-T-T-?????HHHHH?SS--TTTEEE 1H7W|A PF14698.1_ASL_C2_seed 617 112 !Q:13,13|15,15|17,18|32,37|44,48|53,53|60,63|65,76|79,88|90,93|95,97|101,101 Q:0,12|14,14|16,16|19,31|38,43|49,52|54,59|64,64|77,78|89,89|94,94|98,100|102,111 TTTHHHHHHHHHH-T-T??HHHHHHHHHHHHH------HHHHHT--??-GGGS?HHHHTT----T-----?------TT?-------?-T----T---HHH-HTSHHHHHHT 1TJU|A PF14700.1_RPOL_N_seed 126 608 !Q:11,15|23,53|72,85|88,129|133,133|135,137|145,164|167,167|185,185|188,214|240,247|255,257|259,259|269,300|303,320|325,325|327,337|339,339|342,345|347,393|395,395|399,401|418,426|433,438|443,443|445,475|478,478|480,480|486,486|493,497|504,506|511,514|517,528|532,533|535,539|543,544|546,549|553,555|560,573|585,588|590,596 Q:0,10|16,22|54,71|86,87|130,132|134,134|138,144|165,166|168,184|186,187|215,239|248,254|258,258|260,268|301,302|321,324|326,326|338,338|340,341|346,346|394,394|396,398|402,417|427,432|439,442|444,444|476,477|479,479|481,485|487,492|498,503|507,510|515,516|529,531|534,534|540,542|545,545|550,552|556,559|574,584|589,589|597,607 HHHHHHHHTTT--???HHHHHHT??----?????-????????--------???THHHHHHHHHHHHHHHHH--------------HH------------------------------------------HTS?S???HHHHHHT--------------------TS?HHHHHHHHHHHHHHHTT?SS?--?-----------------------BHHHHHHHHHHHHHHHHTTHHHHHH--------HHHHHHS???S?HHHHTTTTT?-------------------------------SS??------------????GGGS?G-----------G-GS????S??---------------------------------------------S?HHH---HHHHHHHHHHHHHHHS--------?SEEEEE------ESTT?T-------------------------------TT?E-EEEEE?HHHHHH-----HHHSTT---TTTT?-??SS?------?----BSS??B???--SSB??B??-?SSS???BSEE?-------------SSHHHHHTTTT-???H-------HHHHHHHHHHT 1CEZ|A PF14705.1_Costars_seed 49 100 !Q:3,3|17,17|19,26|28,29|33,33|35,36|45,46|55,65|78,78|80,82|85,87|94,94|99,99 Q:0,2|4,16|18,18|27,27|30,32|34,34|37,44|47,54|66,77|79,79|83,84|88,93|95,98 GGS?STTHHHHHHHHHH?G--------G--GGT-S??EEEHHHHH--HHHTTTTS--------?--HHHHHHHHHTTS?B???SS???TTTSTT?EEEB? 2KRH|A PF14706.1_Tnp_DNA_bind_seed 54 61 !Q:9,11|28,29|36,36|44,44|57,57|60,60 Q:0,8|12,27|30,35|37,43|45,56|58,59 HHHHHHHTT???SSHHHHHHHHHHHHHH--HHTTTS?HHHHTTT?HHHHHHHHHHHT?TT? 1MUS|A PF14707.1_Sulfatase_C_seed 86 218 !Q:0,0|2,2|4,8|18,30|37,38|41,45|51,55|57,76|81,84|86,88|93,93|95,98|101,102|104,104|111,111|114,115|117,135|140,142|152,158|170,184|191,192|194,195|197,198|202,204|209,211|214,216 Q:1,1|3,3|9,17|31,36|39,40|46,50|56,56|77,80|85,85|89,92|94,94|99,100|103,103|105,110|112,113|116,116|136,139|143,151|159,169|185,190|193,193|196,196|199,201|205,208|212,213|217,217 ?S?S-----EEEEEETTE-------------EEEEEE??TT?-???EEEES?????S????-------------???TTTS----S-??SSST-T????SS-?E-EEETTT?TT??S??----------------?STTT---TSHHHHHHH-------HHHHHHHHTTS?---------?????TTSHHH--H--S??GGG???SSSS---SS???E 1N2K|A PF14709.1_DND1_DSRM_seed 24 84 !Q:0,1|15,18|24,24|28,29|33,33|35,35|52,64 Q:2,14|19,23|25,27|30,32|34,34|36,51|65,83 ??HHHHHHHHHHHHT????EEEEE-EEE??SSS?E-EEEEEEETTEEEEEEE-------------SSHHHHHHHHHHHHHHHHH 3ADL|A PF14710.1_Nitr_red_alph_N_seed 73 45 !Q:12,17|19,19|31,34|45,45 Q:0,11|18,18|20,30|35,44 HHHHGGGTGGGE------E-EEETTTTEEEE????GGGHHHHHHH- 1Y5I|A PF14711.1_Nitr_red_bet_C_seed 141 92 !Q:0,2|4,6|10,17|19,21|24,24|28,29|36,36|48,48|73,80|88,89 Q:3,3|7,9|18,18|22,23|25,27|30,35|37,47|49,72|81,87|90,91 ???B???SSS???-----B---TT-BTS??GGGBSS?HHHHHHHHSTT?HHHHHHHHHHHHHHHHHHHHHHTT????---?HHHHHHT??HH 1Y5I|B PF14714.1_KH_dom-like_seed 596 109 !Q:0,2|18,24|26,27|30,32|34,34|37,42|49,54|57,57|67,69|72,74|78,79|95,98|101,103 Q:3,17|25,25|28,29|33,33|35,36|43,48|55,56|58,66|70,71|75,77|80,94|99,100|104,108 ???HHHHHHHHHHHHHHS--?-??-E--ET---T-EE----??EEEEEE------EE-TTTTEEEEE---ES?--GGG??HHHHHHHHHHHHHHH-??-TT???EEEEE 4DCS|A PF14715.1_FixP_N_seed 213 60 !Q:1,6|8,9|12,14|16,19|21,21|23,28|49,49|56,59 Q:0,0|7,7|10,11|15,15|20,20|22,22|29,48|50,55 S??????S??BT---T----B?B??????HHHHHHHHHHHHHHHHHHHH-STTSTT???? 3MK7|C PF14716.1_HHH_8_seed 351 101 !Q:4,5|7,7|11,11|23,30|33,33|48,50|53,54|58,60|62,63|67,67|72,76|79,79|83,87|95,95 Q:0,3|6,6|8,10|12,22|31,32|34,47|51,52|55,57|61,61|64,66|68,71|77,78|80,82|88,94|96,100 HHHH--H-HHH-HHHHHHHHHHT----??--HH-HHHHHHHHHHHHSS-?-SS-?HHH---H--HTT?STTT-----TS-STT??---HHHHHHH-HHHHT 8ICZ|A PF14717.1_DUF4465_seed 22 257 !Q:4,8|13,19|21,24|26,28|35,37|41,46|52,57|64,64|67,70|73,73|75,75|79,79|81,81|85,86|92,92|94,96|109,110|131,132|135,143|147,147|149,152|155,158|160,160|162,163|173,174|176,180|183,188|199,200|202,208|210,211|213,213|218,218|222,222|235,235|237,238|241,241|244,244|248,249 Q:0,3|9,12|20,20|25,25|29,34|38,40|47,51|58,63|65,66|71,72|74,74|76,78|80,80|82,84|87,91|93,93|97,108|111,130|133,134|144,146|148,148|153,154|159,159|161,161|164,172|175,175|181,182|189,198|201,201|209,209|212,212|214,217|219,221|223,234|236,236|239,240|242,243|245,247|250,256 EEEE-----ETTE-------E-?--S---EEEEEE???STT-----?GGGTS--??-?SBTTSS?SS----SS?E-EEE-E-ESS??BTTTT?B???EEEEETTEEEEE??EEEEEEEEEEBHHHHHHHHH??ST---------TGG-G----GS??--T-T-?EEEEEEEET--T-----SS-----?EEEEEEEETT--E-------E??S?EEEE?GGG?EESEEEEEEEES?E--ET-TE-ESS??EEEEEEE 4JQR|A PF14718.1_SLT_L_seed 96 95 !Q:0,1|21,29|45,49|51,51|53,53|55,62|65,66|77,77|90,90|93,93|95,95 Q:2,20|30,44|50,50|52,52|54,54|63,64|67,76|78,89|91,92|94,94 ??HHHHHSHHHHHHHHHHHTT?--------HHHHHHHHHHHHTTS?----H-H-H--------HH--HHHHHHHHTT?HHHHHHHHHHTT?TT?H- 1SLY|A PF14720.1_NiFe_hyd_SSU_C_seed 163 90 !Q:8,9|19,19|21,22|33,33|35,35|40,41|45,45|53,53|57,57|60,61|63,63|69,73|84,84|88,89 Q:0,7|10,18|20,20|23,32|34,34|36,39|42,44|46,52|54,56|58,59|62,62|64,68|74,83|85,87 HSSBGGGS-?TTHHHHHTT?B??STTSHHHHHT?B?GGGT??GGG?BSSTTTT?BTT-TT--B?TTTTT?????TTSTTHHHHS?TTS?? 3RGW|S PF14721.1_AIF_C_seed 23 148 !Q:8,15|32,34|38,38|45,47|51,57|60,60|69,69|71,71|77,77|79,113|133,134|136,136|147,147 Q:0,7|16,31|35,37|39,44|48,50|58,59|61,68|70,70|72,76|78,78|114,132|135,135|137,146 HHHHHTTT????????EEEEEETTTEEEEEEE???TTS?EEEEEE???TTS-------SH-HHHHHHHS?S?HHHHT?S????????????-?????---??-???----????EEEEEEESSSSEEEEEEES??S?HHHHHHHHHH? 1M6I|A PF14725.1_DUF4466_seed 6 350 !Q:0,13|15,15|22,22|24,24|28,30|43,44|48,49|60,62|65,65|68,68|75,86|90,90|96,96|98,100|112,112|114,114|117,134|144,145|165,165|176,179|188,188|190,190|193,193|197,198|202,202|204,204|208,208|215,215|222,223|229,230|234,235|243,243|246,247|253,253|255,258|261,266|274,276|281,281|284,290|297,299|302,302|307,310|313,313|319,319|334,336|339,339|349,349 Q:14,14|16,21|23,23|25,27|31,42|45,47|50,59|63,64|66,67|69,74|87,89|91,95|97,97|101,111|113,113|115,116|135,143|146,164|166,175|180,187|189,189|191,192|194,196|199,201|203,203|205,207|209,214|216,221|224,228|231,233|236,242|244,245|248,252|254,254|259,260|267,273|277,280|282,283|291,296|300,301|303,306|311,312|314,318|320,333|337,338|340,348 ??????????????S?EEEEEE?S?TTS???TTSEEEEEEEEE??TTT??EEEEEEEESS???TT?EE?SEEEEE-----------?TTS?EEEEE?B???EEETTEEEEEB?S?BS------------------EEEEEEEEE??GGGTTSEEEEEEEEEETTS?EEEEEEEEEE????EEEEEEEE?S-SS?EEE??STT?S?EEE?HHHHHH?GGGGGG??EEEEE?-SST--TTSEEEE?TT??GGGST-T????TT????-?EEEEESS???HHHH?SS?-?????HHHHHH???TT?BSEE????TT?EEEEE?TTSSEEEEEEEEEE--?SS?EEEEEEEEE? 4EI0|A PF14729.1_DUF4467_seed 24 111 !Q:0,0|19,19|24,24|28,29|31,33|52,52|54,55|58,58|60,64|74,75|81,82|86,93|102,104|110,110 Q:1,18|20,23|25,27|30,30|34,51|53,53|56,57|59,59|65,73|76,80|83,85|94,101|105,109 ?HHHHHHHHHHHHHHHHHH-HHHS-TTB??S-??GGGSEEEEEGGGTEEEEE-E??BT-T????-EEEEEEEET--TEEEE-?TTS-----?--HHHHHHHS-??SEEEE? 4EBG|A PF14730.1_DUF4468_seed 50 112 !Q:6,6|10,12|14,14|33,33|36,36|38,38|55,56|64,68|70,71|74,79|107,107 Q:0,5|7,9|13,13|15,32|34,35|37,37|39,54|57,63|69,69|72,73|80,106|108,111 EEEEEE?TTS--?H-HHHHHHHHHHHHHHHHTT?ST-T?EEEEEETTTTEEEEEE--EEEEEEE-----E-?SS?-----EEEEEEEEEEEEEEETTEEEEEEEEEE-EEET 4JHY|A PF14731.1_Staphopain_pro_seed 6 172 !Q:0,2|8,12|36,40|44,46|48,49|55,55|57,57|66,66|80,80|88,88|93,93|100,100|114,114|127,127|140,142|149,156|163,164|168,168|171,171 Q:3,7|13,35|41,43|47,47|50,54|56,56|58,65|67,79|81,87|89,92|94,99|101,113|115,126|128,139|143,148|157,162|165,167|169,170 ???EEEES?????HHHHHHHHHHHHHHHHHHHHHTT?????EEE???B??EETTS?B?SSEEEEEE-ETTEEEEEEEEEE?SGGGGGS?TTTS?EEEEEE?TTHHHHHHTSSSS?EEEEEEETTEEE-EEETTEEEEEEE???TTTTTS????????HHHHHH??EEE?TT? 1X9Y|A PF14732.1_UAE_UbL_seed 74 118 !Q:4,4|8,8|23,24|27,27|36,37|41,41|45,54|69,80|82,83|86,86|97,102|112,112|114,116 Q:0,3|5,7|9,22|25,26|28,35|38,40|42,44|55,68|81,81|84,85|87,96|103,111|113,113|117,117 EEEE?TTT?BHHHHHHIIIIIIT??SS?EEEESSSS??EEE?SSS----------SSSTTGGGSBGGGG------------T??TT?EEEEEETTTT------EEEEEEEEE?S???T 1Y8Q|B PF14734.1_DUF4469_seed 29 127 !Q:9,11|28,33|36,41|44,44|51,58|62,71|75,76|92,93|96,97|101,101|109,111|117,118|121,121 Q:0,8|12,27|34,35|42,43|45,50|59,61|72,74|77,91|94,95|98,100|102,108|112,116|119,120|122,126 EEEEEETTT???SSEEETTSEEEEEEES????-?SS------TT?EEEEEE--------TTT?--------?EEE??GGGEEEEETTEEEEE??TT??SEE-EEEEEEE???SSSSS??SS?EEEEE 4FMR|A PF14743.1_DNA_ligase_OB_2_seed 136 112 !Q:0,8|15,29|31,32|34,38|40,43|47,52|55,56|60,62|73,77|81,81|89,90|92,92|96,102|111,111 Q:9,14|30,30|33,33|39,39|44,46|53,54|57,59|63,72|78,80|82,88|91,91|93,95|103,110 ?????????EEEEEE--------------?S--T-----T--??EEE?-----SS??TTT---HHHHTTTSTT-----TTT?EEEEEEE??S-SSS-----??EEEEEEEE? 1P8L|A PF14748.1_P5CR_dimer_seed 862 176 !Q:0,1|33,34|37,38|57,59|62,76|78,91|93,113|116,121|127,127|129,130|132,134|146,147|151,152|154,154|166,167 Q:2,32|35,36|39,56|60,61|77,77|92,92|114,115|122,126|128,128|131,131|135,145|148,150|153,153|155,165|168,175 ??TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHT--TT??HHHHHHHHHHHHHHHHHH---HH---------------T?------------?S--------------------?HH------HHHHT-T??S---SSSSHHHHHHH--HTT--T-TTHHHHHHHHH--HHHHHHHH 2GER|A PF14749.1_Acyl-CoA_ox_N_seed 150 172 !Q:0,0|15,17|23,26|34,36|38,38|40,41|44,47|49,49|54,54|76,76|79,91|96,112|117,118|126,128|132,133|139,140|144,147|153,154|171,171 Q:1,14|18,22|27,33|37,37|39,39|42,43|48,48|50,53|55,75|77,78|92,95|113,116|119,125|129,131|134,138|141,143|148,152|155,170 ?HHHHHHHHHSSHHH---HHHHH----HHHHHHH---T?G--GG??--S?GGGS?HHHHHHHHHHHHHHHHHHHHH-HT??-----------SHHH-----------------HHHH--HHHHHTT???TTH--HHHHT--HHH----HHHHH??HHHHHHHTGGGGGTSS? 1W07|A PF14759.1_Reductase_C_seed 153 116 !Q:15,22|25,25|28,30|37,37|40,40|42,44|46,47|52,52|54,58|61,61|74,78|93,97|103,106|110,110|115,115 Q:0,14|23,24|26,27|31,36|38,39|41,41|45,45|48,51|53,53|59,60|62,73|79,92|98,102|107,109|111,114 EEEEEETTEEEEEEE?------?TT?SE---EEEEEE-GG-G---T--EEEE-E-----EE-ETTEEEEEEEES?----HHHHHHHHHHHHHT?-???HHHHT---?TTS?GGGG? 3LB8|A PF14760.1_Rnk_N_seed 110 47 !Q:0,3|19,23|28,30|43,43|47,47 Q:4,18|24,27|31,42|44,46 ????EEEHHHHHHHHHHHH-----HTTT???TTHHHHHHHHHT?EEE- 3BMB|A PF14765.1_PS-DH_seed 177 426 !Q:4,4|6,6|10,11|13,14|16,16|26,27|40,40|47,47|63,68|72,79|84,85|89,90|92,92|95,95|97,98|101,106|117,117|122,135|143,163|173,173|175,196|201,201|205,206|209,213|215,218|227,229|231,231|235,235|239,240|244,246|249,249|254,259|261,266|268,269|271,271|278,279|282,284|288,300|303,304|317,318|323,331|333,334|336,336|339,339|345,345|353,362|365,369|377,379|382,382|385,385|388,390|400,401|405,405|419,419|425,425 Q:0,3|5,5|7,9|12,12|15,15|17,25|28,39|41,46|48,62|69,71|80,83|86,88|91,91|93,94|96,96|99,100|107,116|118,121|136,142|164,172|174,174|197,200|202,204|207,208|214,214|219,226|230,230|232,234|236,238|241,243|247,248|250,253|260,260|267,267|270,270|272,277|280,281|285,287|301,302|305,316|319,322|332,332|335,335|337,338|340,344|346,352|363,364|370,376|380,381|383,384|386,387|391,399|402,404|406,418|420,424 BTTB-S-EEE??T--T?SSEEEEEEE?-TTTSGGGGGEEE-TTEEEE?HHHHHHHHHHHHHHH?-----SSS-------?EEEE--EEE??S?EE-E?-TT?----?EEEEEEEEEE-TTEE--------------EEEEEEE?????????????????????EEEEEEEEE-E-------------?????????HHHH-HHH??EE-----E?---THHHHHHH---H-HTT-EEE-?GGG??-EE-EEEE-----?S------S--E-EEEEEE??TT???GGG------------?SS-?HHHHHHHHHGGG--GGST---------T??S?TT?EEEEE-EEEEEEE??----????SE-----EEEEEEE---EE?SS?TT---EEEEEEEEE?-TTS?EEEEEEEEEEEEE?GGGGT? 2VZ8|A PF14785.1_MalF_P2_seed 57 209 !Q:1,1|12,12|17,18|28,29|35,35|46,47|49,57|61,62|64,69|73,84|95,97|100,103|112,113|123,123|127,128|133,133|147,158|160,160|164,165|172,173|187,195|197,197|202,202|204,205|207,207 Q:0,0|2,11|13,16|19,27|30,34|36,45|48,48|58,60|63,63|70,72|85,94|98,99|104,111|114,122|124,126|129,132|134,146|159,159|161,163|166,171|174,186|196,196|198,201|203,203|206,206|208,208 B?HHHHHHHHHH?EEEE--EEEEEEEEE--EETTE-EEEEEEETTT??E---------EEE??B??----SSS------------EEEEEEEESS-??SS????HHHHHHTH--HHHTTEEEE?TTS?-EEEE?SSSEEEEEEESEE------------E?SSS-?EEETTT??EEEEETTTTEEEE???????-?S?EESS?B??B?T 3PUW|F PF14786.1_Death_2_seed 4 148 !Q:0,1|10,10|34,34|38,40|49,51|54,54|60,60|64,64|79,79|82,83|95,95|102,102|116,116|129,136|143,147 Q:2,9|11,33|35,37|41,48|52,53|55,59|61,63|65,78|80,81|84,94|96,101|103,115|117,128|137,142 ??TTSBGGGS?HHHHHHHHHHHHGGGHHHHHHHH?BSS?-?HHHHHSTT???HH-HHGGG?BSS?HHHHHHHHHHHHHS?TT??HHHHHHHHHHT?SSSTTS?BHHHHHHHHHHTT?HHHHHHHHHHTT????????SSSTTS????? 1D2Z|B PF14787.1_zf-CCHC_5_seed 12 36 !Q:0,2|4,4|8,8|13,13|17,19|28,35 Q:3,3|5,7|9,12|14,16|20,27 ???B?TTT?SSBS?TTT???SEEGGGEE???----- 1DSV|A PF14788.1_EF-hand_10_seed 12 52 !Q:0,42 Q:43,51 ???????????????????????????????????????????HHHHHHHHS 1DJZ|A PF14789.1_THDPS_M_seed 68 44 !Q:1,2|6,6|27,27|30,34|42,42 Q:0,0|3,5|7,26|28,29|35,41|43,43 S??EEE-ETTEEEESTTHHHHHHHHTT-TS-?-??EEEEESS?B 3FSY|A PF14790.1_THDPS_N_seed 21 175 !Q:13,13|16,19|30,30|33,33|36,36|44,45|49,51|67,70|80,81|99,101|103,106|119,120|123,131|141,145|163,163|166,166|168,169 Q:0,12|14,15|20,29|31,32|34,35|37,43|46,48|52,66|71,79|82,98|102,102|107,118|121,122|132,140|146,162|164,165|167,167|170,174 HHHHHHHHHHHTS-TT????SEEEEEEEEE?SS?TT?EEEEEES??EES-??HHHHHHHHHHHHHTT????TTSSEEEEE??HHHHHHHHHHTGGGTTS---S--??HHHHHHHHHHHT??TT---------SEEEEEESS?????SHHHHHHHHHHHHTTSS?TT?S??TTHHH 3R5B|A PF14791.1_DNA_pol_B_thumb_seed 209 136 !Q:6,7|22,22|24,24|27,27|30,30|34,47|49,50|53,82|84,87|89,90|92,92|94,114|125,129|133,133 Q:0,5|8,21|23,23|25,26|28,29|31,33|48,48|51,52|83,83|88,88|91,91|93,93|115,124|130,132|134,135 HHHHHH??HHHHHHHHHHHHHT-T?EE?SS?EEE--------------T--TE------------------------------E----E--E?S---------------------SHHHHHHHTT?????GGG?SS 8ICZ|A PF14792.1_DNA_pol_B_palm_seed 47 219 !Q:0,0|15,15|22,22|25,33|38,38|45,45|57,57|60,60|64,66|68,82|84,92|105,111|120,130|133,141|143,154|162,208|216,217 Q:1,14|16,21|23,24|34,37|39,44|46,56|58,59|61,63|67,67|83,83|93,104|112,119|131,132|142,142|155,161|209,215|218,218 ?EEHHHHHHHHHHHH-HHHHHH?SS--------?EEEE?HHHHTT?SEESSEEEEEE?TT?STT---T----------??--?T---------HHHHHHHHHHHT-------TTSEEEEE-----------EE--------?S------------SEEEEEE????------------------------?---?-----????--???EEEEEEE??G 8ICZ|A PF14793.1_DUF4478_seed 51 114 !Q:0,0|5,7|10,14|22,22|24,29|43,49|53,53|61,61|79,80|90,90|112,113 Q:1,4|8,9|15,21|23,23|30,42|50,52|54,60|62,78|81,89|91,111 ?EEEE???TT?????HHHHHTT-S??????HHHHHHHHHHHHH???????SSS?TTTTTTT?EEEEEEETTEEEEEEES??GGGEETTEE?HHHHHHHHHHHHHHHHHHHSS?? 3GH1|A PF14794.1_DUF4479_seed 90 77 !Q:0,6|21,21|23,24|40,52|68,76 Q:7,20|22,22|25,39|53,67 ???????EEEEEETTEEEEEE-T--TEEEEEEEETGGGTS-????-???????HHHHHHHHHHHHHTT????????? 3BU2|A PF14795.1_Leucyl-specific_seed 9 58 !Q:10,10|13,13|16,18|27,27|29,33|42,42|46,47 Q:0,9|11,12|14,15|19,26|28,28|34,41|43,45|48,57 EEEEEEEEEE?SS?EE-??HHHHHHHT?S?????HHHHHTTT?EEE??TTSSEEEEEE 2V0G|A PF14801.1_GCD14_N_seed 11 54 !Q:0,3|5,6|9,9|18,19|25,26|29,29|46,47 Q:4,4|7,8|10,17|20,24|27,28|30,45|48,53 ????S??TT?EEEEEETT??EEEEE??TT?EEEETTEEEEHHHHTT??TTEEEE 1I9G|A PF14803.1_Nudix_N_2_seed 89 37 !Q:0,0|2,2|6,7|9,11|15,17|20,20|23,23|35,36 Q:1,1|3,5|8,8|12,14|18,19|21,22|24,34 ?B?TTT??B-?-EEE??-TT?SS?EEEETTTTEEE?? 3CNG|A PF14804.1_Jag_N_seed 270 60 !Q:18,18|20,22|27,27|30,31|36,38|40,49|51,51|59,59 Q:0,17|19,19|23,26|28,29|32,35|39,39|50,50|52,58 EEEESSHHHHHHHHHHHH-T??-GGGE-EE--EEEE??-B?????--???B?EEEEEEE? 3GKU|A PF14805.1_THDPS_N_2_seed 262 97 !Q:13,13|17,19|22,25|27,28|48,48|53,53|55,57|59,64|67,78|82,82|96,97 Q:0,12|14,16|20,21|26,26|29,47|49,52|54,54|58,58|65,66|79,81|83,95 HHHHHHHHHHHHT-GGG??-TT----T??HHHHHHHHHHHHHHHHTSS?SEEE-E---T------TE------------EEE?HHHHHHHHHHHHH?- 1KGQ|A PF14809.1_TGT_C1_seed 5 70 !Q:0,0|2,3|6,6|9,10|35,36|61,61|64,69 Q:1,1|4,5|7,8|11,34|37,60|62,63 ?S??SS?EE??SSGGGGSHHHHHHHHHHHHHHHHH??EEEETTTEEEETTTTTSTTTTTEE?SS?????? 1IT8|A PF14810.1_TGT_C2_seed 62 78 !Q:12,12|22,27|32,33|37,37|43,43|47,47|53,53|58,58|62,62|74,74 Q:0,11|13,21|28,31|34,36|38,42|44,46|48,52|54,57|59,61|63,73|75,77 HHHHHHHHHHHH?TTGGGGTTT-----?EEEE?-SSS?EEEEE?SSS-EEEEE?TTTS?EEE?HHHHHHHHHHS?TTT 1IT8|A PF14814.1_UB2H_seed 119 108 !Q:1,1|4,7|20,20|23,24|26,26|28,35|41,46|49,49|51,54|62,66|70,75|85,85|97,97|100,100|102,102|107,107 Q:0,0|2,3|8,19|21,22|25,25|27,27|36,40|47,48|50,50|55,61|67,69|76,84|86,96|98,99|101,101|103,106 E?TT????HHHHHHHHHHTT?EE?-S-S---??---STTEE------EE?S----SEEEEEE?????SSS-?-???EEEEEEEET-TEEEEEEETTT-TE-E?SSEE? 3FWL|A PF14815.1_NUDIX_4_seed 286 215 !Q:3,3|6,7|12,13|16,16|20,21|25,25|30,30|33,34|37,37|39,59|61,64|67,67|70,86|88,89|93,108|111,112|114,116|118,122|125,129|135,135|138,138|144,145|147,148|152,155|159,168|170,184|195,195|197,197|199,199|201,202|204,206 Q:0,2|4,5|8,11|14,15|17,19|22,24|26,29|31,32|35,36|38,38|60,60|65,66|68,69|87,87|90,92|109,110|113,113|117,117|123,124|130,134|136,137|139,143|146,146|149,151|156,158|169,169|185,194|196,196|198,198|200,200|203,203|207,214 EEE-EE?-SSSE--EE-EEE??SSS-TTTT?EE??EE-E----?--?--?----?-?---H----HH-HH-----------------H--HHT?--??---?-???---EE--E-?-S----?SE-----EEEEE?SS-EEEEE--E--EEE----EEE?-----??--S??-----------?-TTEEEEEGGG-G-G-G--S???HHHHHHHH 3EEU|A PF14819.1_QueF_N_seed 126 115 !Q:0,5|9,10|23,24|26,27|29,29|31,32|34,34|44,44|48,48|52,52|56,56|71,71|85,85|87,87|89,90|109,110 Q:6,8|11,22|25,25|28,28|30,30|33,33|35,43|45,47|49,51|53,55|57,70|72,84|86,86|88,88|91,108|111,114 ??????GGG??EEEHHHHHHHTT??S--S?S?-E-EEEEEEETT?EEE?TTS?EEE?EEEEEEETTSSEEE?HHHHHHHHHTTTT?B?S?-HHHHHHHHHHHHHHHHTS??EEEE 3UXJ|A PF14821.1_Thr_synth_N_seed 302 104 !Q:0,0|7,12|14,18|20,20|28,29|31,32|36,37|42,43|45,50|53,53|61,66|80,82|85,89|91,91 Q:1,6|13,13|19,19|21,27|30,30|33,35|38,41|44,44|51,52|54,60|67,79|83,84|90,90|92,103 ?EEETTS-?----S---??B?HHHHHHH-?S-?TTS??EEES--S???-??HH-HHHTTTT?----?HHHHHHHHHGGGG---TT?----S?HHHHHHHHHHHH 4F4F|A PF14823.1_Sirohm_synth_C_seed 15 77 !Q:0,2|20,22|25,25|28,29|55,55|60,60|74,76 Q:3,19|23,24|26,27|30,54|56,59|61,73 ???HHHHHHHHHHHHHHHHH---HS?SG--GGHHHHHHHHHHHHHHHHHHHGGGB?HHHH-HHHHHHHHTTTTS??? 1KYQ|A PF14824.1_Sirohm_synth_M_seed 20 31 !Q:15,15 Q:0,14|16,30 EETTTEEEEEEESSS?HHHHHHHHHHHHHHH 1KYQ|A PF14826.1_FACT-Spt16_Nlob_seed 75 208 !Q:0,1|24,26|32,32|40,40|42,44|46,47|49,52|65,67|76,77|80,81|100,104|106,107|109,113|115,117|120,120|128,131|133,133|135,136|152,154|156,159|162,162|165,165|169,169|172,177|192,193|198,198|203,203 Q:2,23|27,31|33,39|41,41|45,45|48,48|53,64|68,75|78,79|82,99|105,105|108,108|114,114|118,119|121,127|132,132|134,134|137,151|155,155|160,161|163,164|166,168|170,171|178,191|194,197|199,202|204,207 ??HHHHHHHHHHHHHHHHSHHHHH---HTSTT?SEEEEEE?S-??T--T????HHHHHHHHHHSS-??SSEEEEEE--SS--EEEEEEEHHHHHHHGGGG-----S?-T-----T--?SS-EEEEEEE--?-S?H--HHHHHHHHHHHHHHH---T----TT-SE-EEE?TT?--???SHHHHHHHHHHGGG--GGGS-EEEE?HHHH 3BIP|A PF14827.1_Cache_3_seed 258 188 !Q:9,9|14,15|18,19|22,23|25,26|30,58|71,71|74,74|84,84|88,89|91,91|96,98|103,109|112,114|120,124|127,129|133,133|135,139|141,141|145,146|148,148|158,163|166,169|171,172|174,174 Q:0,8|10,13|16,17|20,21|24,24|27,29|59,70|72,73|75,83|85,87|90,90|92,95|99,102|110,111|115,119|125,126|130,132|134,134|140,140|142,144|147,147|149,157|164,165|170,170|173,173|175,187 HHHHHHHHT?HHHH--HH--TT--S-?GGG------------------?----------SHHHHHHHHHHH-TT?SEEEEEETT?BBS??S-SGGG---TTSB??---?-GG---GTGGG-----GT-??EEE-E-----E?SSS--S?EEEEEEEEE---?--TT----S-?E-EEEEEEEEEHHHH 1P0Z|A PF14829.1_GPAT_N_seed 19 78 !Q:0,2|7,8|25,25|27,27|50,50|62,62|76,77 Q:3,6|9,24|26,26|28,49|51,61|63,75 ???GGGG??SHHHHHHHHHHHHHTT?S?HHHHHHHHHHHHHHHHHHHHTT?TTHHHHHHHHH-HHHHHHHHHHHHS?? 1IUQ|A PF14830.1_Haemocyan_bet_s_seed 27 118 !Q:4,4|11,15|18,18|27,27|29,30|32,35|37,37|39,39|42,43|50,52|56,60|63,63|68,68|77,84|88,89|101,101|103,104|109,111|113,114|117,117 Q:0,3|5,10|16,17|19,26|28,28|31,31|36,36|38,38|40,41|44,49|53,55|61,62|64,67|69,76|85,87|90,100|102,102|105,108|112,112|115,116 HTTS?EEEEEE?????SS?EEEEEEEE?S--S----S?E-EE--EEEEEE???TTS?????SS?EEEE?HHHHHTTT??------TTS??EEEEEEEESSS?B??GGGS???B??EE? 3L6W|A PF14832.1_Tautomerase_3_seed 26 187 !Q:0,1|8,8|13,14|16,16|18,18|32,39|43,43|45,46|50,50|57,58|61,63|72,72|75,91|100,100|105,115|118,119|122,123|130,130|141,143|147,147|149,149|159,159|163,163|169,172|175,175 Q:2,7|9,12|15,15|17,17|19,31|40,42|44,44|47,49|51,56|59,60|64,71|73,74|92,99|101,104|116,117|120,121|124,129|131,140|144,146|148,148|150,158|160,162|164,168|173,174|176,186 ??EEEEEE?TTSS?-H-H-HHHHHHHHHHHHH--------HHT-T??GGG?EEEEEE??TT---SEEETTEE?SS-----------------EEEEEEEE-ETTS---------??SH--HH--HHHHHH-HHHHHHHHHH---GGG-T?EEEEEEEEE?GGG?EETTB????TT?HHHHHHHHHTS 3N4D|A PF14833.1_NAD_binding_11_seed 132 177 !Q:30,30|33,34|43,43|46,46|50,50|52,54|57,60|62,65|67,72|75,80|87,90|92,95|97,101|103,103|120,121|126,130|136,136|142,142|144,144|146,146|148,148|150,150|152,152|154,154|156,158|160,160|162,162|164,164|170,170|172,172|175,175 Q:0,29|31,32|35,42|44,45|47,49|51,51|55,56|61,61|66,66|73,74|81,86|91,91|96,96|102,102|104,119|122,125|131,135|137,141|143,143|145,145|147,147|149,149|151,151|153,153|155,155|159,159|161,161|163,163|165,169|171,171|173,174|176,176 THHHHHHHHHHHHHHHHHHHHHHHHHHHHH-TT??HHHHHHHH-TT-STT?B---HH----H----H------HT------HHHHTT----T----S??-??S-SBHHHHHHHHHHHHHH--HTTT????-HHHHH-HHHHH-H-H-H-H-H-H-H?--T-T-S-BGGGG-H-HH-H 2I9P|A PF14834.1_GST_C_4_seed 7 117 !Q:18,18|26,26|33,40|61,62|69,70|88,91|104,104|116,116 Q:0,17|19,25|27,32|41,60|63,68|71,87|92,103|105,115 SHHHHHHHHHHHHHHHHS?HHHHHHS?THHHHS????????HHHHHHHHHHHHHHHHHTTT??SSTTSS??HHHHHHHHHHHHHHTTT????HHHHHHHHHHHT?HHHHHHHHHHH? 3BBY|A PF14835.1_zf-RING_6_seed 5 65 !Q:9,9|13,13|15,16|19,19|21,23|27,28|30,30|42,42|46,47|49,49|51,51|54,57 Q:0,8|10,12|14,14|17,18|20,20|24,26|29,29|31,41|43,45|48,48|50,50|52,53|58,64 HHHHHHTTS?SSS?S??SS?B???SSS??B?TTTGGGGTTTB?SSS??B?S?SS????HHHHHHH 1JM7|B PF14836.1_Ubiquitin_3_seed 6 104 !Q:9,10|20,20|23,23|38,39|43,43|58,60|70,71|73,86|88,88|95,96|100,103 Q:0,8|11,19|21,22|24,37|40,42|44,57|61,69|72,72|87,87|89,94|97,99 EEEEEETTE--EEEEEEEEE?TT?BHHHHHHHHHHHTT??SSS?EEEEEEETTTEEEE???TTSBTTTTT??T--------------T?EEEEEE??TTS???? 4A3O|A PF14840.1_DNA_pol3_delt_C_seed 3 125 !Q:11,11|27,28|49,49|54,54|63,65|68,68|80,80|103,103|105,105|120,124 Q:0,10|12,26|29,48|50,53|55,62|66,67|69,79|81,102|104,104|106,119 HHHHHHHHTTS?HHHHHHHHHHTTTTT??HHHHHHHHHHHHHHHHHHHH?SSSS?HHHHHHHH???SS?TTHHHHHHHHS?HHHHHHHHHHHHHHHHHHHHTT?S?THHHHHHHHHHTTS????? 1XXH|A PF14841.1_FliG_M_seed 335 91 !Q:0,0|12,12|24,25|37,37|39,43|45,45|57,65|83,90 Q:1,11|13,23|26,36|38,38|44,44|46,56|66,82 ?HHHHHHHHTTS?HHHHHHHHHTS-?HHHHHHHHHTS?G-----G-GHHHHHHHHHH????----?HHHHHHHHHHHHHHSTT???????? 3HJL|A PF14842.1_FliG_N_seed 137 112 !Q:0,1|18,18|29,29|31,31|45,49|63,65|72,74|76,76|89,91|102,102 Q:2,17|19,28|30,30|32,44|50,62|66,71|75,75|77,88|92,101|103,111 ??HHHHHHHHHHHHHHHS?HHHHHHHHHH-S?HHHHHHHHHHHHT?????HHHHHHHHHHHHH---HHHHTT???S?HHHHHHHHHHHS???HHHHHHHHHH-HHHHHHHHH 3HJL|A PF14843.1_GF_recep_IV_seed 30 158 !Q:1,2|6,6|9,9|28,37|39,39|43,44|48,48|52,52|57,57|64,65|69,71|75,78|96,102|104,105|113,114|117,119|123,157 Q:0,0|3,5|7,8|10,27|38,38|40,42|45,47|49,51|53,56|58,63|66,68|72,74|79,95|103,103|106,112|115,116|120,122 S??TTB?TT?BSSSSGGGBSSBSSEESS----------S?EES??SSS?SSS?EEEE-TTEEEE??TTB???TTS---?SBSSSSSTTBSSBSSEE-------E--TTEEESS??SS??-BTT?-???????????????????-????????????? 3QWQ|A PF14844.1_PH_BEACH_seed 47 126 !Q:0,2|23,23|32,51|54,54|61,61|68,70|73,73|85,85|104,104|110,110|112,113|125,125 Q:3,22|24,31|52,53|55,60|62,67|71,72|74,84|86,103|105,109|111,111|114,124 ???EEEEEEEEETTEEEEEEEEE?SSEEEEEE?-------------------TT?HHHHTS?HHHHHH???TT?EEEGGGEEEEE-EEEETTEEEEEEEEETTS?EEEEE?S-?HHHHHHHHHTS? 1MI1|A PF14845.1_Glycohydro_20b2_seed 183 479 !Q:0,3|5,6|9,10|14,19|27,27|31,31|36,36|39,41|43,44|46,95|97,98|107,107|111,129|134,340|343,346|350,366|368,378|382,384|386,390|394,405|408,423|425,425|430,446|450,456|471,471 Q:4,4|7,8|11,13|20,26|28,30|32,35|37,38|42,42|45,45|96,96|99,106|108,110|130,133|341,342|347,349|367,367|379,381|385,385|391,393|406,407|424,424|426,429|447,449|457,470|472,478 ??--S??SE--EEE------EEEEEEE?SSS?EEEE?TT?--S??T--------------------------------------------------T?-HHHHHHHH-HHH-------------------HHHH-----------------------------------------------????????-------------------------------------------------------------------------?????-----------------------------------------------------------------------???EE?---EEE-----------------E-----------EES---S?--??SSS------?---??TT????------------E-EEEE-----------------SSS----?--EEEEESSHHHHHHH-HHHHHHH 3NSM|A PF14847.1_Ras_bdg_2_seed 35 142 !Q:0,0|6,6|10,10|16,17|19,21|35,50|60,60|62,87|93,114|118,120|126,129|138,141 Q:1,5|7,9|11,15|18,18|22,34|51,59|61,61|88,92|115,117|121,125|130,137 ?EEEEE?STT?EEEEE??S--?HHHHHHHHHHHHT???-------------TTSEEEEEE?S--------------------------SSEEE????????????--????????EEE---EESSS????HHHHHHTT???? 1K8R|B PF14848.1_HU-DNA_bdg_seed 21 132 !Q:8,17|21,21|24,27|30,30|42,43|47,47|70,70|74,74|86,87|89,90|94,95|97,100|103,103|112,112|116,116|130,130 Q:0,7|18,20|22,23|28,29|31,41|44,46|48,69|71,73|75,85|88,88|91,93|96,96|101,102|104,111|113,115|117,129|131,131 EEEEEEEE??????????EEE-EE????EE?HHHHHHHHHHH-?TTS?HHHHHHHHHHHHHHHHHHHTTT?EEE?SSEEEEEEEES??G--GGS??T----TT?EEEEEEEE?HHH-HHHHHTEEEEEEE-E 4FMR|A PF14849.1_YidC_periplas_seed 388 639 !Q:5,5|8,8|10,10|14,14|16,19|23,24|31,34|36,37|40,40|45,55|57,57|60,67|69,71|75,78|82,82|85,85|87,92|101,102|105,111|113,113|119,120|122,122|124,129|131,132|134,134|136,139|141,141|144,144|146,147|150,161|165,166|169,169|174,174|176,176|178,178|180,186|198,210|220,223|227,227|231,232|237,238|244,251|254,282|289,293|295,298|300,300|302,313|315,317|320,320|322,326|333,357|361,362|365,365|367,373|387,393|395,398|400,400|402,409|413,414|421,421|424,433|437,447|452,453|456,474|476,481|485,485|488,489|494,495|504,516|521,540|542,548|550,574|576,585|587,591|593,602|604,606|610,615|618,618|621,628|634,638 Q:0,4|6,7|9,9|11,13|15,15|20,22|25,30|35,35|38,39|41,44|56,56|58,59|68,68|72,74|79,81|83,84|86,86|93,100|103,104|112,112|114,118|121,121|123,123|130,130|133,133|135,135|140,140|142,143|145,145|148,149|162,164|167,168|170,173|175,175|177,177|179,179|187,197|211,219|224,226|228,230|233,236|239,243|252,253|283,288|294,294|299,299|301,301|314,314|318,319|321,321|327,332|358,360|363,364|366,366|374,386|394,394|399,399|401,401|410,412|415,420|422,423|434,436|448,451|454,455|475,475|482,484|486,487|490,493|496,503|517,520|541,541|549,549|575,575|586,586|592,592|603,603|607,609|616,617|619,620|629,633 EEEEE?SS?E-EEE-E----TBT??EEEEEE----E--EE-ESST-----------T?SS--------E---EEE----EEE?SS?E------EEEEEEEE--ST-------T?TTSGG--G?S-??---B-?B?S?---S-EE-E??TT?----------?EEE--EE-EEEE?T-T-S-?-----EEEEEEEEETT---?--------?EEEEEEEEE-?-?SSS?EEE--EEEE--EEEEE--------SS????------?????????-?-?---??-EEEEEE?----S----S?S------------S--?EE?H-----HHHHTT----------??------------?EEE--ES-S?------EEEEEESSEEEEE-------E----E-E--------SSS-?EEEEEE-EE----------ETT-----------EEEE--EE-------------------E?-?--?EEE?TT-?EEEE--EEEEEEEE?-----------?HHHH--------------------H-------H-------------------------H----------S-----T----------T???HHH------HH-HH--------HHHTS????? 3BLC|A PF14850.1_Pro_dh-DNA_bdg_seed 114 126 !Q:1,16|31,31|38,110 Q:0,0|17,30|32,37|111,125 T????????????????HHHHHHHHHHTTSS?HHHHHH????????????????-??-??????????????????????-----?--??---??????????????????HHHHHHHHHHHHGGG 2FZM|A PF14852.1_Fis1_TPR_N_seed 63 36 !Q:20,20|34,35 Q:0,19|21,33 HHHHHHHHHHHHHSSSHHHH-HHHHHHHHHHSTT?? 2PQN|A PF14853.1_Fis1_TPR_C_seed 60 54 !Q:15,15|30,30|33,33|50,50|53,53 Q:0,14|16,29|31,32|34,49|51,52 HHHHHHHHHHHHHTS?HHHHHHHHHHHHHH?TT?HHHHHHHHHHHHHHHH-TT? 3KD7|A PF14859.1_Colicin_M_seed 2 281 !Q:0,0|2,7|11,12|20,27|29,30|39,44|69,69|72,72|99,100|107,110|113,113|117,118|123,124|127,129|147,148|151,152|158,161|173,176|179,180|194,194|202,202|215,215|240,241|250,253|260,263|268,270|280,280 Q:1,1|8,10|13,19|28,28|31,38|45,68|70,71|73,98|101,106|111,112|114,116|119,122|125,126|130,146|149,150|153,157|162,172|177,178|181,193|195,201|203,214|216,239|242,249|254,259|264,267|271,279 ?B??????TTT??SSGGGGS????????S??THHHHHHH------HHHTTSHHHHHHHHHHHHHHHHHH?SS?HHHHHHHHHHHHHHHHHHHHHHHSTT??HHHHHH--??SS?GGG??HHHH??SB???STTHHHHHHHHHHHSTT??EE??GGGTT????GGGSSTTTTTT????BS??EEEEEEEEEGGGT?HHHHHHT?EEEEEEEEEEEE?TTSEEEEEEEEEESSSEEEESTTT??HHHHHHHH----HHHHHB????EEEE???EEEEEEEEE? 3DA3|A PF14860.1_DrrA_P4M_seed 3 123 !Q:0,1|8,8|11,12|15,21|24,29|31,31|33,33|35,37|43,44|63,64|88,88|98,100|120,122 Q:2,7|9,10|13,14|22,23|30,30|32,32|34,34|38,42|45,62|65,87|89,97|101,119 ??HHHHTS?TT??SS?--????SS??---?S?S?S???TTSSS??THHHHHHHHHHHHHHGGG??SHHHHHHHHHHHHTSSHHHHHHS?SSHHHHTTT???HHHHHHHHHHHHHHHTTTT??? 3L0M|A PF14861.1_Antimicrobial21_seed 22 34 !Q:0,2|4,5|16,16|18,18|32,32 Q:3,3|6,15|17,17|19,31|33,33 ???S??HHHHHHHHTS-S?GGGHHHHHHHHHS?T 2L2R|A PF14862.1_Defensin_big_seed 4 85 !Q:0,0|2,2|11,11|23,23|34,40|42,42|46,47|60,63|66,66|69,69|77,77|84,84 Q:1,1|3,10|12,22|24,33|41,41|43,45|48,59|64,65|67,68|70,76|78,83 ?S?STTTTEEE?HHHHHHHHHHS?HHHHHHTTEE-------E?SSS??EETTTTEEEESS?--?TT?EE?TTTHHHH?SSEEEE? 2RNG|A PF14863.1_Alkyl_sulf_dimr_seed 196 191 !Q:0,1|7,7|10,14|20,21|26,26|30,30|44,45|47,48|50,50|56,58|71,72|85,87|93,103|117,129|131,131|134,134|136,136|138,146|154,161|170,170|189,189 Q:2,6|8,9|15,19|22,25|27,29|31,43|46,46|49,49|51,55|59,70|73,84|88,92|104,116|130,130|132,133|135,135|137,137|147,153|162,169|171,188|190,190 ??TTTGG-GT??-??HHHHT-?GGGS?SSS?HHHHHHHHHHHHH?-S??S?GGGTS???HHHHHHHHHHHT--TSHHHHHHHHHH---HHHTT?----------HHHHHHHHHHHHH-------------H?TT?H-H---------HHHHHHH--------HHHHHHHH?SSHHHHHHHHHHHHHHHH?S 4AXH|A PF14864.1_Alkyl_sulf_C_seed 140 176 !Q:0,3|11,11|24,24|30,36|38,40|49,53|56,56|58,62|64,74|88,91|95,103|106,106|113,114|123,123|128,128|139,141|144,144|147,147|159,167|169,171|175,175 Q:4,10|12,23|25,29|37,37|41,48|54,55|57,57|63,63|75,87|92,94|104,105|107,112|115,122|124,127|129,138|142,143|145,146|148,158|168,168|172,174 ????HHHHHHS?HHHHHHHHHHHB?HHHHT-------T?-?EEEEEEET-----TT-T-----E-----------EEEEEEETTEEEE----EET???------TT?SEEEEE-?HHHHHHHH-TTSS?HHHHHHTTSE---EE-EE?TTHHHHHHHTB????-----S???SSS? 4AXH|A PF14865.1_Macin_seed 6 62 !Q:0,1|11,12|17,17|19,21|29,29|33,33|35,35|41,41|44,44|46,46|48,49|52,53|55,55|61,61 Q:2,10|13,16|18,18|22,28|30,32|34,34|36,40|42,43|45,45|47,47|50,51|54,54|56,60 ??BSSHHHHHH??TTTT?S???HHHHHHH-TTT?S?EEEEE?GG-G?S?-TT--T?EEEEE? 2LN8|A PF14867.1_Lantibiotic_a_seed 14 32 !Q:0,2|10,11|16,18|20,22|27,27|30,31 Q:3,9|12,15|19,19|23,26|28,29 ???TTTTTTS??SSSS???S???GGGT?TT?? 2KTN|A PF14869.1_DUF4488_seed 11 153 !Q:0,3|13,13|19,20|28,28|33,33|43,47|51,52|67,73|82,82|101,101|103,107|120,120|123,124|137,137|139,140|143,144|147,152 Q:4,12|14,18|21,27|29,32|34,42|48,50|53,66|74,81|83,100|102,102|108,119|121,122|125,136|138,138|141,142|145,146 ????EEEEEEEEE?SSTTS??EEEEEEE-EEEE?TTSEEEEEE?---?TTS??EEEEEEEEEEEETT-------EEEEEEEE-ESSSGGGTTEEEEEEEEE?T-----TSEEEEEEEEEE?TT??EEEEEEEEEEEE?B??SS??TT---??? 4I95|A PF14870.1_PSII_BNR_seed 23 355 !Q:0,1|3,3|6,7|13,13|15,15|18,20|28,29|33,33|53,53|56,63|65,69|100,100|103,106|109,109|112,112|123,123|132,136|152,152|154,176|183,183|187,187|202,202|205,205|208,208|213,214|218,218|225,225|228,230|232,232|247,250|258,270|272,272|277,278|280,280|290,290|292,292|301,301|312,312|315,315|324,326|334,338|345,345|354,354 Q:2,2|4,5|8,12|14,14|16,17|21,27|30,32|34,52|54,55|64,64|70,99|101,102|107,108|110,111|113,122|124,131|137,151|153,153|177,182|184,186|188,201|203,204|206,207|209,212|215,217|219,224|226,227|231,231|233,246|251,257|271,271|273,276|279,279|281,289|291,291|293,300|302,311|313,314|316,323|327,333|339,344|346,353 ??B?SS??EEEEE?S?SS--?EEEEEES--SSS?EEEEETTTEEEEESSTTSS?EE??---???S??-??EEEEEEEETTEEEEEEETTEEEEESSTTSS?EE????TT?SS?EEEEEEEETT-EEEEEETT---??EEEESSTTSSEEEEE?S??-------------------??EEEEEE?TTS?EEEEETTSSEEEEE?TT?SS?EEEE??SSS?EEEEEE?TT---S?EEEEETTTEEEEEE----TTEEEEE??----------?B?TTSS??S?EEEEEESSS-S?EEEEESTT?EEEESSTTSS?EE?GGGTTSSS???EEEEEET-----TEEEEE?STTEEEEE? 2XBG|A PF14873.1_BNR_assoc_N_seed 37 170 !Q:0,9|14,15|17,17|22,22|24,25|34,34|37,38|40,42|50,50|53,53|67,72|79,80|82,82|85,85|88,88|94,95|98,99|103,103|112,114|121,125|130,132|145,146|149,150|153,153|156,157|169,169 Q:10,13|16,16|18,21|23,23|26,33|35,36|39,39|43,49|51,52|54,66|73,78|81,81|83,84|86,87|89,93|96,97|100,102|104,111|115,120|126,129|133,144|147,148|151,152|154,155|158,168 ?????----?EEEE??S?EETT?S??EEEEEEEE?SS??E---EEEEEEE?TT?BSGGGEEEEEEEE???-??GGGGGG??S?SS?SS?SSSTT??SS??GGG?EEEEEEES?-?SEEEEE-----EEEE??-SSEEEEEEEEEE?-TT??TT?EE??EEEEEEETTEE? 4FJ6|A PF14878.1_DLD_seed 4 120 !Q:0,1|8,9|26,27|37,37|40,40|51,51|62,62|76,78|94,96|99,102|104,104|114,116 Q:2,7|10,25|28,36|38,39|41,50|52,61|63,75|79,93|97,98|103,103|105,113|117,119 ??GGGGSS??GGGHHHHHHHHHHHTT??HHHHHHHHH-HT?TTHHHHHHHH?TTHHHHHTTS?HHHHHHHHHHHHS???HHHHHHHHHHHHSSS???SB????B?HHHHHHHHT???TTT 3PSI|A PF14883.1_GHL13_seed 12 439 !Q:2,2|7,8|30,31|37,37|40,40|43,43|46,46|48,48|53,54|58,58|61,61|63,63|76,78|80,80|86,86|89,89|91,96|98,98|100,100|102,104|106,109|119,125|127,129|132,138|141,143|145,145|148,148|166,169|175,175|178,182|185,202|206,209|212,212|219,222|224,246|248,248|255,255|266,275|293,296|299,302|304,306|309,309|330,332|340,340|347,347|354,362|365,367|395,413|423,423|432,433|438,438 Q:0,1|3,6|9,29|32,36|38,39|41,42|44,45|47,47|49,52|55,57|59,60|62,62|64,75|79,79|81,85|87,88|90,90|97,97|99,99|101,101|105,105|110,118|126,126|130,131|139,140|144,144|146,147|149,165|170,174|176,177|183,184|203,205|210,211|213,218|223,223|247,247|249,254|256,265|276,292|297,298|303,303|307,308|310,329|333,339|341,346|348,353|363,364|368,394|414,422|424,431|434,437 EE?HHHH??SSHHHHHHHHHHHHHHHHHTT??EEEEE?EE?TT?SS?B?EESS??SSS?BS?S?HHHHHHHHHHHH??-E-EEEEE?SS?B??---?T-T-S?--B????GGGHHHHHT-?-----G---GG-------GG--?B?TT?HHHHHHHHHHHHHHHHH-???SEEEE?TT????-TT??---------------?SHH----HH-HHHHHT----T----?---------?--------S?HHHHHT?HHHHHHHHHH----------HHHHHHHHHHHHHHHHH----HH----H--?TT?EEEEEEEHHHHHSGGGGGGT???HHHHHHH?SEEEEE?GGGGSS--??-----HH---HHHHHHHHHHHHHHTSTTHHHHEEEEE??????--??---?????-HHHHHHHHH-HHHHHTTT??EEEE? 4F9D|A PF14887.1_HMG_box_5_seed 4 92 !Q:0,7|64,69|77,77|83,83|87,91 Q:8,63|70,76|78,82|84,86 ????????HHHHHHHHHHHHHHHHHTTSTHHHHHHHHHHHHHTTGGGHHHHHHHHHHHHHHHHH------HHHHTTS?GGGSS-SSS????? 1L8Y|A PF14888.1_PBP-Tp47_c_seed 14 169 !Q:2,2|13,16|19,22|24,29|32,32|39,42|46,48|52,52|65,66|85,85|88,88|92,92|94,95|99,101|108,109|114,114|121,121|130,132|146,147|155,159|161,162 Q:0,1|3,12|17,18|23,23|30,31|33,38|43,45|49,51|53,64|67,84|86,87|89,91|93,93|96,98|102,107|110,113|115,120|122,129|133,145|148,154|160,160|163,168 TT?TTBEEEEETT----EE???-B??????TT?EEEEEE----ESS???STT?SEEEEEEEEETT??HHHHHHHHTTEEEEEEEE?TT?TTS?S??EEE???BTTTEE??SSSS?EEEEEE?TTSGGGTT?-?SEEEEEEEEETTS??EEEEEEE?????S??EEEEEE 1O75|A PF14889.1_PBP-Tp47_a_seed 13 185 !Q:0,4|25,43|48,48|53,54|65,65|75,75|77,78|89,97|105,105|108,109|115,115|117,118|120,120|122,123|130,130|163,164|167,167|170,176|179,184 Q:5,24|44,47|49,52|55,64|66,74|76,76|79,88|98,104|106,107|110,114|116,116|119,119|121,121|124,129|131,162|165,166|168,169|177,178 ?????EEEEEEEEEHHHHHHHHGGG????----???????????SSSS?EEEE??SHHHHHHTTT-EEEEEEEEE?S?-EEEEEEEEEE---------EEEEEEE?EE?-EEEEE?T--T?S--EEEETT-EEEEEEEEEEEEEEEEEEEEEGGGHHHHHHHH??EE?TT?-----?TT-----? 1O75|A PF14890.1_Intein_splicing_seed 5 532 !Q:1,1|20,21|23,23|40,41|59,60|65,65|68,68|82,189|192,192|198,494|501,501|517,517|521,521 Q:0,0|2,19|22,22|24,39|42,58|61,64|66,67|69,81|190,191|193,197|495,500|502,516|518,520|522,531 T?EEEETTTTEEEESGGGTT??S?EEEEEETTTTEEEEEE??EEEEEEEEEEEEEEETT??EEEE?TT?EEEETTEEEEGGG----------------------------------------------------------------------------------------------------------??TT?EEEEE??????????------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------???????????EEEEEE-EEEEEEEEEEEEEEE?TTT?EEEETTEEEE 1DQ3|A PF14894.1_Lsm_C_seed 14 65 !Q:10,12|17,17|41,41|43,44|60,64 Q:0,9|13,16|18,40|42,42|45,59 HHHHHHHHHH---HSTT?EEEETTTTEEEETTTEEEETTEE-E??SHHHHHHHHHHHHHH---?? 1M5Q|1 PF14896.1_Arabino_trans_C_seed 7 405 !Q:0,16|28,31|45,45|51,52|57,58|62,63|73,73|77,77|79,79|81,116|118,118|121,122|126,127|129,130|134,135|139,141|144,146|150,152|157,159|162,168|170,171|175,175|185,187|191,200|207,207|215,216|222,222|226,226|228,228|231,231|233,233|244,244|247,248|257,259|263,264|268,270|272,273|275,275|290,291|298,298|304,306|310,315|320,343|360,360|363,366|374,404 Q:17,27|32,44|46,50|53,56|59,61|64,72|74,76|78,78|80,80|117,117|119,120|123,125|128,128|131,133|136,138|142,143|147,149|153,156|160,161|169,169|172,174|176,184|188,190|201,206|208,214|217,221|223,225|227,227|229,230|232,232|234,243|245,246|249,256|260,262|265,267|271,271|274,274|276,289|292,297|299,303|307,309|316,319|344,359|361,362|367,373 ?????????????????HHHHHHHHHHH----STTGGGGTEEEES?GGGGB??BSSS?-HHH--HTTSSEEES?BTT?S?S??????????????????--??????-?????????B?SS??TTS??B??STT??GGG???EE???SSS???EEEE???EE??----?S??TTB?SEEEEEEEE???GGG----------EEEEEE?HHHHHTT??SEEEE?EEE-S?SS-S?EEEEEEGGGS?TT??EEEEEEEE???STT??EEE???B??B?EEHHHHHTTTSEEE??HHHHTT?TTSEE???GGG??????EEEE????????????-???????????TTTTEEEEEEEEEETT?TT????EEEEEEE???-????-?????????????????????? 3PTY|A PF14905.1_OMP_b-brl_3_seed 316 1385 !Q:1,2|5,7|9,9|11,13|15,17|19,37|40,40|42,42|44,45|47,48|50,51|54,55|60,61|63,63|66,67|69,74|77,81|84,84|89,92|98,100|103,193|198,199|211,213|217,219|221,222|226,227|230,231|233,234|236,237|241,242|245,246|249,255|258,302|306,308|311,312|328,328|330,331|333,337|340,340|347,347|357,357|361,362|366,368|370,474|476,476|480,486|492,493|495,496|504,506|508,508|510,510|512,517|519,519|522,525|527,527|530,531|537,540|543,544|546,549|552,553|556,576|579,581|584,585|587,594|596,597|599,599|601,601|603,615|617,628|632,632|635,636|639,640|645,646|650,652|654,654|658,659|662,663|668,668|675,685|687,688|691,691|693,695|697,707|719,721|723,726|728,728|730,733|736,737|740,747|749,751|755,758|762,763|766,767|769,771|775,777|779,787|790,792|794,795|797,798|800,809|811,826|832,870|872,875|880,885|888,888|892,893|902,904|907,923|926,931|933,943|945,947|955,955|959,980|982,985|988,990|992,1090|1093,1098|1100,1103|1107,1110|1113,1114|1116,1117|1119,1120|1122,1167|1170,1174|1176,1177|1182,1183|1185,1185|1194,1195|1198,1200|1202,1283|1285,1285|1288,1288|1298,1298|1300,1300|1303,1303|1312,1363|1367,1373|1375,1376|1379,1380|1384,1384 Q:0,0|3,4|8,8|10,10|14,14|18,18|38,39|41,41|43,43|46,46|49,49|52,53|56,59|62,62|64,65|68,68|75,76|82,83|85,88|93,97|101,102|194,197|200,210|214,216|220,220|223,225|228,229|232,232|235,235|238,240|243,244|247,248|256,257|303,305|309,310|313,327|329,329|332,332|338,339|341,346|348,356|358,360|363,365|369,369|475,475|477,479|487,491|494,494|497,503|507,507|509,509|511,511|518,518|520,521|526,526|528,529|532,536|541,542|545,545|550,551|554,555|577,578|582,583|586,586|595,595|598,598|600,600|602,602|616,616|629,631|633,634|637,638|641,644|647,649|653,653|655,657|660,661|664,667|669,674|686,686|689,690|692,692|696,696|708,718|722,722|727,727|729,729|734,735|738,739|748,748|752,754|759,761|764,765|768,768|772,774|778,778|788,789|793,793|796,796|799,799|810,810|827,831|871,871|876,879|886,887|889,891|894,901|905,906|924,925|932,932|944,944|948,954|956,958|981,981|986,987|991,991|1091,1092|1099,1099|1104,1106|1111,1112|1115,1115|1118,1118|1121,1121|1168,1169|1175,1175|1178,1181|1184,1184|1186,1193|1196,1197|1201,1201|1284,1284|1286,1287|1289,1297|1299,1299|1301,1302|1304,1311|1364,1366|1374,1374|1377,1378|1381,1383 E--EE---E-E---E---E???---?-?---?-??---EE-E-E--E--E--EE--EEEE--E-EE--T------TE-----EE-EEEE----EEEEE---EE?--???---??-------------------??????-?-?-------------------?????------------?????--??????-?EEEE--EEEEEEEEEEE?--TTS?--E--EEE--EE--E--E--EEE--EE--EE-------EE?--???----?-?????--?---------?????????-------EEE---EE--EEEEEEEEEEEEEEE-E--E-----TT-EEEEEE-EEEEEEEEE-EEE--EEE---E-??----------?????-?---??????????????------------------------------------------------------???------?---?S-EEE-------EEEEE--E--EEEEEEE---E-E-E------E-TT----E-EE--EEEEE----EE--E----EE--EE---------------------EE---ET--T--------E--E-E-E-------------E------------EEE-EE--EE--EEEE--EEE---E?SSS--EE--EEEE-EEEEEE-?-----??-?B?-SS-S-?-B--------???EEEEEEEEEEE---E----E-E----GG--GT--------E---EEE----EEE--EE--E---EEE---S---------EE---E--E-?T----------T?----------?-?--TTSSS---------------------------------------S?--?EEEE?--?-?EE-EEE--EEEEEEEE---ET-----------------TE------E-----------E---EEEEEEE-EEE----?-----------------T----TS--?B---------------------------------------------------------------------------------??-----?----------SS--?---S----EEE----EE--E--E--E----------------------------------------------EE--?--S--STTT--T-EEEEEEEE--EE---E??--???---------------??????-----------------------------------------?---?----?-??E-EE-EEEEEEEEE-E-TT-EEEEEEEE??----????---?-??--????----????--?----------????---?EEE-------E--EE--EEE? 1PO3|A PF14928.1_S_tail_recep_bd_seed 9 125 !Q:1,2|7,7|14,14|18,18|20,20|25,28|32,45|47,52|56,57|60,63|67,70|73,75|77,85|88,88|91,91|95,96|100,101|106,106|110,113|115,118|124,124 Q:0,0|3,6|8,13|15,17|19,19|21,24|29,31|46,46|53,55|58,59|64,66|71,72|76,76|86,87|89,90|92,94|97,99|102,105|107,109|114,114|119,123 S??HHHH?GGGSSB?TTS?B?TTTT????STT??????????????S???---SSS??TT????SSS????SS???S?????????SS?SS?GGG??GGG??SSTT?SSS????S????EEEEE? 1PDI|A PF14930.1_Qn_am_d_aII_seed 20 122 !Q:0,0|5,5|29,29|32,32|43,43|48,48|72,82|94,95 Q:1,4|6,28|30,31|33,42|44,47|49,71|83,93|96,121 ?GGGS?EEEEEEEEETTTEEEEEEEEEEE?ST-TEEEEEEEEE-ETTS?EEEEEEEEEEETTTEEEEEEEET-----------TEEEEEEEEEE--TTEEEEEEEETTEEEEEEEEEEEETT 1JJU|A PF14938.1_SNAP_seed 62 324 !Q:0,1|9,9|16,18|22,22|26,26|28,29|53,53|71,71|74,74|94,101|104,105|118,118|124,124|144,163|171,172|185,186|199,199|202,202|208,210|228,228|251,252|265,275|290,290|306,308 Q:2,8|10,15|19,21|23,25|27,27|30,52|54,70|72,73|75,93|102,103|106,117|119,123|125,143|164,170|173,184|187,198|200,201|203,207|211,227|229,250|253,264|276,289|291,305|309,323 ??HHHHHHH-HHHHSS???THH-HHH-S??SHHHHHHHHHHHHHHHHHHHHTT?THHHHHHHHHHHHHHHH-TT?HHHHHHHHHHHHHHHHHTT-------?HH--HHHHHHHHHHHH-HHHTT?HHHHHHHHHHHHHHHHHTT-------??-----------HHHHHHH--HHHHHHHHHHTT-?HHHHHHHHHHHH-HH-HHHTT--?HHHHHHHHHHHHHTTSS?TTTGGGHHHHHHHHHHHHHHTT-?HHHHHHHHHGGG???????????HHHHHHHHHHHHTT?TTTHHHHHHHHTTSS???HHHHHHHHHHHHHHH 2IFU|A PF14947.1_HTH_45_seed 27 86 !Q:0,2|15,16|19,19|21,21|31,32|49,51|53,56|59,59|67,67 Q:3,14|17,18|20,20|22,30|33,48|52,52|57,58|60,66|68,85 ???HHHHHHHHHHHH--TT?B?HHHHHHHHT??HHHHHHHHHHHHHTTS---E----EE-ETTEEEE?HHHHHHHHHHHHHHHHHH 1R7J|A PF15009.1_TMEM173_seed 16 360 !Q:0,148|168,175|192,192|194,197|208,211|213,213|215,216|222,223|232,248|255,258|273,273|285,287|292,293|314,318|320,326|333,345 Q:149,167|176,191|193,193|198,207|212,212|214,214|217,221|224,231|249,254|259,272|274,284|288,291|294,313|319,319|327,332|346,359 ------??----------------------------------------????????--------------------------????----????--------???-----------????-----?-----?????????????----?THHHHHHHHHHHTHHHHHH--------HHHHHHHHHHHHHHHH?T????SSEEEEEETT????S?H--HHHST--TEEEEEEE???????????????-?EEEEEE----EETTEEEEEEEEEE?THHHHHHHHTT?--GGGT??HHHHHHHHHHHHHHHHHHHH-----S???????EEEEEE?---?????????HHHHHHHHHHHHHH 4KC0|A PF15028.1_PTCRA_seed 3 170 !Q:0,5|7,8|10,12|33,35|38,41|45,45|49,49|52,53|56,58|83,83|90,97|100,102|104,169 Q:6,6|9,9|13,32|36,37|42,44|46,48|50,51|54,55|59,82|84,89|98,99|103,103 ??????B??B???EEEESSSSEEEEEEEEEEEE???SS????EEE?SSS?EE??EE???EEETTTEEEEEEEEEEEGGGGGTS?SBEEEE????????EE???B????-??????????????----------------------------------------------? 3OF6|D PF15036.1_IL34_seed 5 180 !Q:0,5|7,7|9,9|23,23|36,36|39,40|48,50|58,62|67,68|91,92|98,98|118,122|124,128|138,140|143,143|145,148|150,150|154,154|179,179 Q:6,6|8,8|10,22|24,35|37,38|41,47|51,57|63,66|69,90|93,97|99,117|123,123|129,137|141,142|144,144|149,149|151,153|155,178 ??????S?S?HHHHHHHHHHHHT?HHHHHHHTTTTS?TT??EEEEGGG???HHHHHHH-----HHTT??HHHHHHHHHHHHHHHHHHHHTT??TTSTT-HHHHHHHHHHHHHHHHTTS-----S????-TTTHHHHHH---HH-S????E-EEE?HHHHHHHHHHHHHHHHGGGTSSSS? 4DKF|A PF15040.1_Humanin_seed 9 24 !Q:0,2|21,23 Q:3,20 ???HHHHHHHHHHHHTTSSSS??? 2GD3|A PF15095.1_IL33_seed 4 278 !Q:0,117|122,123|145,145|148,148|156,157|159,164|172,175|180,183|185,187|196,197|216,217|220,221|225,225|231,231|235,235|260,262|267,269|273,273 Q:118,121|124,144|146,147|149,155|158,158|165,171|176,179|184,184|188,195|198,215|218,219|222,224|226,230|232,234|236,259|263,266|270,272|274,277 -------------------------------------------------------------------------?-------------------------------------------?SSSS??EEEEEEEEEEETTTEEEEEEE?SS?EEEEEEE??S??????EEEEEEE????TTTS????S???EEEEEESS--SSEEEEEETTTTEEEEEE??SS??TTT?EEEEE?SSS?EEEEESSSTTEEEEESSSSEEEEE?-?SSTT???GGG?EEEE 4KC3|A PF15110.1_TMEM141_seed 12 102 !Q:0,0|16,16|24,29|65,65|101,101 Q:1,15|17,23|30,64|66,100 ?SSSHHHHHHHHHHHS?SHHHHHH------HHHHHHHHHHHHHHGGGTHHHHHHHHHHTTSSSSS?HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT? 2LOR|A PF15177.1_IL28A_seed 10 165 !Q:0,3|5,7|13,14|37,38|42,42|45,45|48,49|54,54|80,80|104,105|107,120|137,137 Q:4,4|8,12|15,36|39,41|43,44|46,47|50,53|55,79|81,103|106,106|121,136|138,164 ????S???GGGSS??HHHHHHHHHHHHHHHHHHHTSS??BSS?SS?TT??GGGS?GGGHHHHHHHHHHHHHHHHHHHHHH?HHHHHHHHHHHHHHHHHHHHHHT--T?????????-????HHHHHHHHHHTGGGTS?HHHHHHHHHHTHHHHHTHHHHHHHTGG 3OG4|A PF15227.1_zf-C3HC4_4_seed 13 45 !Q:0,0|4,4|7,7|13,13|16,17|28,28|32,32|34,41|45,45 Q:1,3|5,6|8,12|14,15|18,27|29,31|33,33|42,44 ?TTT?SB?SSEEE?TT??EEEHHHHHHH?SSS?S?----???SSS- 2ECJ|A PF15247.1_SLBP_RNA_bind_seed 52 108 !Q:0,3|6,11|20,23|40,55|58,62|66,68|86,86|88,107 Q:4,5|12,19|24,39|56,57|63,65|69,85|87,87 ????HH------HHHHHHHH----HHHHHTSHHHHHHHHH??-?????--?----?SS?????TTS???HHHHHHHHHHHHHHHGG-G------?-----------?? 4L8R|C PF15270.1_ACI44_seed 3 65 !Q:0,3|5,5|11,12|15,15|26,26|40,40|42,42|54,55|64,64 Q:4,4|6,10|13,14|16,25|27,39|41,41|43,53|56,63 --??B?SSGGG??TT?EEETTTTEEE?HHHHHHHHHHHSS?B?SSGGGGTTSSS??EEETTEEE? 3FJU|B PF15275.1_PEHE_seed 27 179 !Q:0,41|75,178 Q:42,74 ????--?????--?????????---????--------?????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH??????-------------------------------------------------------------------------------------------------- 4DNC|D PF15277.1_Sec3-PIP2_bind_seed 101 132 !Q:5,5|12,13|15,15|18,19|22,22|27,29|34,34|36,43|46,49|61,62|67,67|70,70|72,87|95,95|98,104|118,118 Q:0,4|6,11|14,14|16,17|20,21|23,26|30,33|35,35|44,45|50,60|63,66|68,69|71,71|88,94|96,97|105,117|119,131 GGEEE-EEEEEE--E?SS-?TT?EEEE---EEEE?G--------GG?---EEEEEEEEGGG??EEEE?SS?T----------------TEEEEES-SS-------EEEEEESSHHHHH-HHHHHHHHHHHHH 3A58|A PF15283.1_DUF4595_seed 26 287 !Q:3,3|7,7|15,15|24,24|27,27|33,33|44,46|49,54|56,56|59,60|63,67|71,72|74,74|78,78|84,88|90,90|92,92|95,98|100,105|116,116|119,119|121,121|131,140|144,144|148,148|154,154|169,169|172,185|192,194|197,201|203,204|207,213|218,219|224,224|228,231|241,244|247,250|255,269|273,274|279,279|283,283 Q:0,2|4,6|8,14|16,23|25,26|28,32|34,43|47,48|55,55|57,58|61,62|68,70|73,73|75,77|79,83|89,89|91,91|93,94|99,99|106,115|117,118|120,120|122,130|141,143|145,147|149,153|155,168|170,171|186,191|195,196|202,202|205,206|214,217|220,223|225,227|232,240|245,246|251,254|270,272|275,278|280,282|284,286 EEE?TTS?EEEEEEE-EEEEETTE-EE-EEEEE-EEEEEETTEE---EE------E?TT??EE-----EEE--E?TTS?EEEEE-----E-E?TT----S-----?EEEEEEEEEE?TT-S?EEEEEEEEE?---------TTS?EEE-EEEEE?SSTTEEEEEEEETT-EE--------------EEEEEE?-?TT--???B?-TT?---???TTGG--GSTT-GGG---?HHHHHTTTT????SB???-EEEE?-----?????-???EEE--EEEE?TTS?EEE 4GHB|A PF15285.1_BH3_seed 8 25 !Q:0,1|23,24 Q:2,22 ??HHHHHHHHHHHHHHHHHTTTT?? 2P1L|B PF15286.1_Bcl-2_3_seed 3 127 !Q:16,16|19,23|48,51|74,76|96,96|98,98|100,102|125,126 Q:0,15|17,18|24,47|52,73|77,95|97,97|99,99|103,124 HHHHHHHHHHHHHHTT?SS?????HHHHHHHHHHHHHHHHHHHHHHHH????STTGGGGHHHHHHHHHHHHTSS???HHHHHHHHHHHHHHHHTTS?T-T???HHHHHHHHHHHHHHHHTTGGGG?? 3BL2|A PF15289.1_RFXA_RFXANK_bdg_seed 7 144 !Q:0,94|96,99|114,115|135,143 Q:95,95|100,113|116,134 ------------------------------------------------???-------------------------------------???????S????HHHHHHHHHHHHTT??HHHHHHHHHHHHHHHHHSS????????? 2KW3|C PF15291.1_Dermcidin_seed 2 101 !Q:0,47|80,89 Q:48,79|90,100 --------------------------------------------????HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH----------HHHHHHHHHTT 2YMK|A PF15313.1_HEXIM_seed 25 258 !Q:0,41|43,114|116,227|230,230|238,238 Q:42,42|115,115|228,229|231,237|239,257 ??----------------------------------------S------------------------------------------------------------------------S??-----------------------------------------------------------------------------------------------???????????????TT-HHHHHHS?HHHHHHHHHHHHHHHHHHH 3S9G|A PF15401.1_TAA-Trp-ring_seed 23 91 !Q:0,23|25,27|36,36|40,55|61,65|73,74|76,76|79,80|87,88 Q:24,24|28,35|37,39|56,60|66,72|75,75|77,78|81,86|89,90 -----????????-----??????B???EEETTEEE?HHH----------------HHHTS-????SSHHHHT??S?SB??HHHHHH--HH 3EMI|A PF15403.1_HiaBD2_seed 19 66 !Q:0,7|11,11|14,18|23,23|32,34|42,42|45,45|47,47|49,53|55,55|58,60|64,64 Q:8,10|12,13|19,22|24,31|35,41|43,44|46,46|48,48|54,54|56,57|61,63|65,65 ????????BTT?TT---??TTTS?HHHHHHHT?--GGGTTSB?TT?B?T-----T-SS---BSS?T 1S7M|A PF15405.1_PH_5_seed 42 166 !Q:12,12|14,21|41,42|50,51|57,57|61,69|71,72|77,99|101,106|113,124|133,138|142,142|147,147|164,164 Q:0,11|13,13|22,40|43,49|52,56|58,60|70,70|73,76|100,100|107,112|125,132|139,141|143,146|148,163|165,165 EEEEEEEEETTS?E--------EEEEEESSEEEEEEEEEET--TEEEESS??EEGGG?EEE---------E??TTTS???--------------------S??????SHHHHT------------SSEEEEEE----??GGG?EEEE?SSHHHHHHHHHHHHHH-H 2Z0Q|A PF15409.1_PH_8_seed 11 92 !Q:0,8|11,11|13,13|35,41|50,50|65,65|68,68|74,74 Q:9,10|12,12|14,34|42,49|51,64|66,67|69,73|75,91 ---------TT?S?EEEEEEEETTTTEEEEESSSS??--???EEEEGGGS-EEEEETTTTEEEEE?SS?EEEEE?SSHHHHHHHHHHHHGGG 2RSG|A PF15410.1_PH_9_seed 16 161 !Q:0,1|12,12|16,16|18,20|22,25|33,33|44,49|52,68|74,75|77,79|81,91|93,100|103,103|106,106|111,113|116,121|123,123|132,132|136,136|142,142|156,157|160,160 Q:2,11|13,15|17,17|21,21|26,32|34,43|50,51|69,73|76,76|80,80|92,92|101,102|104,105|107,110|114,115|122,122|124,131|133,135|137,141|143,155|158,159 --EEEEEEEEEE?STT?B?--S????EEEEEEE-ETTEEEEESS------HH-----------------HHHHT??S---S-----------S???-----EE?TT?EEEE--?SS----??S-SSSEEEEE?TTS?EEEEE?SSHHHHHHHHHHH--HH? 1BTN|A PF15413.1_PH_11_seed 7 155 !Q:6,9|12,13|15,15|18,19|29,34|44,79|82,83|85,86|94,96|99,100|103,103|105,105|115,128|132,132|138,138 Q:0,5|10,11|14,14|16,17|20,28|35,43|80,81|84,84|87,93|97,98|101,102|104,104|106,114|129,131|133,137|139,154 EEEEEE----EE??S-SS??EEEEEEEEE------TTEEEEESS------------------------------------TT??S??EEEESTT???EE??TT?S?SSSSEEEEE?-------------SSS?EEEEE?SSHHHHHHHHHHHHHH 1EAZ|A PF15414.1_DUF4621_seed 4 329 !Q:0,14|20,22|32,32|36,36|54,54|57,60|62,65|77,77|87,88|90,91|94,95|104,104|106,106|118,118|121,121|135,136|144,147|155,155|165,166|184,184|199,200|202,202|205,205|218,218|240,240|243,243|253,253|257,257|259,259|261,265|269,269|280,280|290,291|301,302|305,308|312,312|324,328 Q:15,19|23,31|33,35|37,53|55,56|61,61|66,76|78,86|89,89|92,93|96,103|105,105|107,117|119,120|122,134|137,143|148,154|156,164|167,183|185,198|201,201|203,204|206,217|219,239|241,242|244,252|254,256|258,258|260,260|266,268|270,279|281,289|292,300|303,304|309,311|313,323 ???????????????EEEEE???EEEEHHHHS?GGG?TTEEEETTEEEEEEEEE?EE????S????SEEEEEEEEEE?GGGGGGSSS??B??BS??EEEEEEEE?S?EEEEEEEEEEE?SS?EEEEEEEEEEESS??EEEEESS????TTSEEEE?SSHHHHHTT??SEEEEEEEEEHHHHHHS?TTSEEEEEEEEEEE??B?TT?EEEEEEEETTSS?TTTHHHHTSSSEEEEEEEEEE?SS?EEEEEEEEE?TTS?B?S?????EEE?SSEEEEEEEE?TTTGGGGGG??EEEEEEEEE??SS????BTT?EEEEEEEEEEE????? 4H3W|A PF15415.1_DUF4622_seed 3 342 !Q:0,1|8,10|13,14|16,28|33,33|39,45|47,49|52,52|60,60|63,64|66,66|70,73|80,82|86,87|93,93|96,96|98,98|101,101|103,103|105,106|108,114|118,118|130,132|134,134|140,142|145,147|150,151|159,159|165,175|181,183|198,198|201,203|217,218|222,227|229,231|235,237|239,243|246,246|255,259|262,262|266,266|274,275|282,282|303,303|308,308|325,326|339,341 Q:2,7|11,12|15,15|29,32|34,38|46,46|50,51|53,59|61,62|65,65|67,69|74,79|83,85|88,92|94,95|97,97|99,100|102,102|104,104|107,107|115,117|119,129|133,133|135,139|143,144|148,149|152,158|160,164|176,180|184,197|199,200|204,216|219,221|228,228|232,234|238,238|244,245|247,254|260,261|263,265|267,273|276,281|283,302|304,307|309,324|327,338 ??EEEEEE???EE??B?----????????SSBS-SSSTT----???B???TT?EEEEEEE?TT??B?GGG?---EEEEEE???TTS??EEEEE-EE?T-TS?E-E--E?--????EEE?SEEEEEEEEES???B?TTSSB???SS???EE??TTBTTTS?EEEEE???????????EEEEE???EEESSEEEEEEEEE?TT???EEEEEEEEEEEEE??TTS?----?S???GGG---T?????EE?EEEEEEEE?--??EE?TTS?EEEEEEE??EEESSS?EEEEEEEEETTEEEEEEEEE?SEEE?TTBEEEEEEEEEESSS-?EEEEEEEEEEEE??? 4H40|A PF15416.1_DUF4623_seed 6 466 !Q:0,14|28,28|33,33|44,46|48,48|52,52|66,66|70,70|74,78|81,82|92,92|95,95|106,110|113,113|117,117|124,127|131,136|150,150|159,161|165,167|180,183|186,188|191,193|215,215|219,219|221,221|233,234|241,241|248,249|251,251|253,253|255,256|261,261|265,265|290,290|294,294|299,300|304,304|312,312|317,317|331,331|334,335|339,341|343,343|345,352|374,375|380,384|391,392|409,410|412,412|418,422|426,427|437,437|441,441|464,465 Q:15,27|29,32|34,43|47,47|49,51|53,65|67,69|71,73|79,80|83,91|93,94|96,105|111,112|114,116|118,123|128,130|137,149|151,158|162,164|168,179|184,185|189,190|194,214|216,218|220,220|222,232|235,240|242,247|250,250|252,252|254,254|257,260|262,264|266,289|291,293|295,298|301,303|305,311|313,316|318,330|332,333|336,338|342,342|344,344|353,373|376,379|385,390|393,408|411,411|413,417|423,425|428,436|438,440|442,463 ????????-??????EEEEEEEEETTTT?EEEE?EEETTTTEEE???B?TTS?TTSEEEEEEESTT?EES?SEE?????TT??EEEEEEEEE?SS?EEEEEEEEEB?????SB?TTS?EEEEEE----GGG----??GGGGSTTEEEEEE?SSEEEEEE???TTT???SEEEEHHHHHTT????EE???TT???SSEEEEEEEEETTEEEEEEEB?STT-S?EEEEEESSTTS??EEEEEE?GGGSTT??S?B?S??EEEE?TTS?EEEEEEBTTSSEEEEEEEETTTEE?GGG?EEEE??GGG?SSEEEEE?TTSS?EEEEETTEEEEEE?TT??EEE---E?S---??---TTEEEEEEEEETTEEEEEEEE??BSTT?????EEEEEE??SSSSHHHHHHHHHHSS??S?SEEEE?????BTT??EEEEEEEEE?TTS?EEEEEEEEEETTTEEEEEEEEB?? 4FTD|A PF15421.1_Polysacc_deac_3_seed 8 494 !Q:7,7|10,13|15,16|20,21|27,27|36,36|39,39|53,54|56,56|59,78|81,87|93,101|104,104|106,107|110,111|115,115|119,119|123,125|129,130|133,136|141,142|146,146|149,150|152,153|158,159|162,163|175,175|180,182|185,185|189,189|205,205|213,216|220,222|225,225|238,239|247,250|252,254|258,259|261,262|265,266|271,271|273,277|281,283|298,299|301,301|305,307|309,310|317,325|331,333|348,349|354,354|368,370|388,389|393,394|396,397|406,407|417,417|420,421|427,432|444,445|465,465|480,480|493,493 Q:0,6|8,9|14,14|17,19|22,26|28,35|37,38|40,52|55,55|57,58|79,80|88,92|102,103|105,105|108,109|112,114|116,118|120,122|126,128|131,132|137,140|143,145|147,148|151,151|154,157|160,161|164,174|176,179|183,184|186,188|190,204|206,212|217,219|223,224|226,237|240,246|251,251|255,257|260,260|263,264|267,270|272,272|278,280|284,297|300,300|302,304|308,308|311,316|326,330|334,347|350,353|355,367|371,387|390,392|395,395|398,405|408,416|418,419|422,426|433,443|446,464|466,479|481,492 EEEEEEE?TT?-??S??EEE??SSGGG?SEEEEEEE?TT?HHHHHTHHHHHTT??B?SS----------------????HH-------HHHHT???------TT?B??SS??EEE?SSS?EEE???EEE??TT---?GGGG??EEE?TT??S??GGGS??SS??HHHHHHHHTTT?EEEB???SS?GGG?SHHHHHHHHHHHHHH-HHHHTTT????EEE?-?TT?HHHHHHHTTSTT??EEEESSS?---B???TTT??S??TT--EEEE?B?????TTS???HHHHHHHHHHHHHT--S?GGG???E--EEEESS-------??HHHHH---HHHHHHHHTSTTTT??EEEE?HHHHHHHHHHHHH???EEEEEETTEEEEEEEEE??SSS??S??EEEEEEET??GGGEEEEEE?TT??EEEEE------EETTEEEEEEE??TTHHHHHHHHHHHHHHSTT?HHHHHHHHHHHTTS?SSHHHHHHHHHT? 4DWE|A PF15425.1_DUF4627_seed 3 227 !Q:0,8|13,15|17,20|29,29|38,38|40,40|44,44|51,51|53,53|57,57|64,64|67,67|70,72|83,83|85,87|104,104|115,116|118,118|122,122|124,126|133,134|136,137|140,140|147,147|152,153|156,158|160,161|176,176|183,185|188,189|193,194|197,197|209,211|215,215 Q:9,12|16,16|21,28|30,37|39,39|41,43|45,50|52,52|54,56|58,63|65,66|68,69|73,82|84,84|88,103|105,114|117,117|119,121|123,123|127,132|135,135|138,139|141,146|148,151|154,155|159,159|162,175|177,182|186,187|190,192|195,196|198,208|212,214|216,226 ?????????SSTT??-S????EESSGGGS?TTSEEEEE?S?TTS?EEEEEE?S?TTS?EEEEEE?TT?SS???TTTEEEEEEE?S???SSEEEEEEEEEESSTT?EEEEEEEESS??B?TTS?B???EEEETT??T--TT?TTSBSS?EEEE??ST---T??EEEEEEEEEEEEES?SSBTTT--?TT??EEE??TT?HHHHSEEEEEE-??STT?EEEEEEEEEEE 3SEE|A PF15447.1_NTS_seed 205 60 !Q:14,14|20,22|24,42|45,45|48,48|51,59 Q:0,13|15,19|23,23|43,44|46,47|49,50 SHHHHHHHHHHHHH-HHHHH---S---------?--------?TT-GG-GT????????? 2XU0|A PF15490.1_Ten1_2_seed 29 156 !Q:0,4|7,8|12,12|14,16|20,20|22,22|25,25|46,52|56,56|59,59|67,67|70,71|73,73|75,87|90,90|100,104|108,123|133,133|136,137|155,155 Q:5,6|9,11|13,13|17,19|21,21|23,24|26,45|53,55|57,58|60,66|68,69|72,72|74,74|88,89|91,99|105,107|124,132|134,135|138,154 ?????EE??HHH-H---HTT?S?TT?EEEEEEEEEEEETTTTEEEE-------EEE?SS?EEEEEEE?TT--T?S???---------?TT?EEEEEEEEE??---TTS??--------------EEEEEEEEE?TT??HHHHHHHHHHHHHHHHH? 4JOI|C PF15493.1_YrpD_seed 8 262 !Q:0,1|14,21|30,31|33,34|36,37|39,42|45,45|58,68|70,70|80,86|92,93|97,98|106,108|110,111|115,120|128,129|131,131|134,134|149,153|161,170|175,175|186,190|202,202|211,213|215,216|231,233|235,240|252,253|256,256 Q:2,13|22,29|32,32|35,35|38,38|43,44|46,57|69,69|71,79|87,91|94,96|99,105|109,109|112,114|121,127|130,130|132,133|135,148|154,160|171,174|176,185|191,201|203,210|214,214|217,230|234,234|241,251|254,255|257,261 ??SBTTEEEEEEEE???----?SEEEEEEE??S??B??S----SS?EEEEEEEEEETT-----------S?EEEEEEEEE-------TTTTE--EEE--EEEETTB???E--EEE-----?HHHHSTT??B?TT?EEEEEEEEEETTEE-----EEEEEEE----------BTTS?EEEEEEEETT?????EEEEEEEEEEE?SSGGGGGG???E--EEEEEEEEEETTEE???E------EEEEESEEEEE-?SS?EEEEE 4HFS|A PF15494.1_SRCR_2_seed 47 113 !Q:3,3|20,21|37,37|39,43|56,57|60,61|67,71|78,78|80,80|87,89|91,91|93,94|97,97|105,108|110,112 Q:0,2|4,19|22,36|38,38|44,55|58,59|62,66|72,77|79,79|81,86|90,90|92,92|95,96|98,104|109,109 SSS?BEEEEETTTTEEEEEB??TTHHHHHHHHHHHTT?S----?EEEEEEEEHHHH??TT??SEEEE----?TTTGGG?S?STTSEE---E-E??SS?EEEEEEE?-??S??? 2OY3|A PF15495.1_Fimbrillin_C_seed 35 120 !Q:0,0|9,9|15,15|17,20|23,24|28,45|50,51|53,53|66,66|68,69|73,76|81,87|91,93|99,101|112,112|114,119 Q:1,8|10,14|16,16|21,22|25,27|46,49|52,52|54,65|67,67|70,72|77,80|88,90|94,98|102,111|113,113 ?EEEGGGEE-EEEEE?B?--?TT??STT-----------------?TTSB-?B?TTEEEEEEEEEE?S??BSS????SBTT-------BTT???SBGGG???SEEEEEEEEE?B?????? 4JRF|A PF15507.1_DUF4649_seed 14 72 !Q:6,6|10,10|49,52|66,67|71,71 Q:0,5|7,9|11,48|53,65|68,70 EEEEEE?TTS?EEEEEESSHHHHHHHHHHEEEETTTTSBEEEEEETTEE????SBGGGHHHHHHHS??GGG? 4IAJ|A PF15510.1_CENP-W_seed 6 103 !Q:0,17|29,29|32,32|35,35|42,56|81,81|85,85|101,102 Q:18,28|30,31|33,34|36,41|57,80|82,84|86,100 -------------?????HHHHHHHHHHH?TT?EE?TTHHHH---------------HHHHHHHHHHHHHHHHHHHHHHTT?SSB?HHHHHHHHHHHHHHT?? 3VH6|W PF15513.1_DUF4651_seed 20 62 !Q:0,2|18,19|23,25|29,29|37,38|45,45|61,61 Q:3,17|20,22|26,28|30,36|39,44|46,60 ???HHHHHHHHHHHHTTT??EEE???SEE?SSSSEEE??EEETTS?EEEEEEETTEEEEEE? 2M7O|A PF15514.1_ThaI_seed 2 202 !Q:3,3|32,32|52,52|58,61|64,64|67,68|86,87|89,89|93,96|107,110|119,119|130,130|142,142|149,151|155,157|162,162|175,175|182,190|201,201 Q:0,2|4,31|33,51|53,57|62,63|65,66|69,85|88,88|90,92|97,106|111,118|120,129|131,141|143,148|152,154|158,161|163,174|176,181|191,200 HHH?HHHHHHHHHHHHHHHHHHHHTSEETTEE?TTHHHHHHHHHHHHHHHHH?GGGEE????TT?SS??EEETTEEEEEEEEESSS??S?EEE????HHHHHHHHHH????SEEEEEEE?TTSEEEEEEE?HHHHHHHHHHH?HHHHEE???TTS???SEEE?HHHHHHHHHSTT?EEEEEE?????????TTHHHHHHHH? 3NDH|A PF15515.1_MvaI_BcnI_seed 21 311 !Q:11,12|16,25|44,49|51,51|58,62|65,65|68,68|75,81|84,84|97,97|100,100|104,112|120,120|124,130|134,139|145,145|148,154|156,156|158,158|164,165|167,170|172,172|177,177|182,186|196,196|202,204|211,213|223,229|243,244|250,253|256,257|259,260|279,280|285,285|287,288|294,296|306,306|309,309 Q:0,10|13,15|26,43|50,50|52,57|63,64|66,67|69,74|82,83|85,96|98,99|101,103|113,119|121,123|131,133|140,144|146,147|155,155|157,157|159,163|166,166|171,171|173,176|178,181|187,195|197,201|205,210|214,222|230,242|245,249|254,255|258,258|261,278|281,284|286,286|289,293|297,305|307,308|310,310 HHHHHHHHHTT??EEE----??????HHHHHHHHHHHHHHHHHT?????-S?EEEEHH-----HH-HT?EEEEEE???----SB-STTHHHHHHHHH?EE?TTS?--------EEEEEEE?SSS????---TTS------SEEEE-EE-------E-E-TTTTE--E----E-EEEE-ETTS?----EEEEEEEEE-HHHHH---HHHHHH???EEEEEEEEE-------EETTEEEEEEEEE--EEEEE--??HH--H--HHHHHHHTSEEEEEEEEE??SSTT-T--TSEEE???EEEEEHHHH-HH-H 2OA9|A PF15516.1_BpuSI_N_seed 4 166 !Q:0,1|5,5|36,37|56,57|65,65|73,73|90,90|96,99|105,105|114,115|119,120|124,124|129,129|133,135|139,139|162,164 Q:2,4|6,35|38,55|58,64|66,72|74,89|91,95|100,104|106,113|116,118|121,123|125,128|130,132|136,138|140,161|165,165 ??TTS?HHHHHHHHHHHHHHHHHHHHTGGGTEEEEE--EEEETTEEEEEEEEETTT??EEEEEEE?SSHHHHT?HHHHHHHHHHHHHHGG-GEEEE----EEEEE?SSEEEEEE??TTS??GGG?BBTT?SEE???TTS?HHHHHHHHHHHHHHHHHHHHTT???B 3S1S|A PF15517.1_TBPIP_N_seed 9 102 !Q:4,4|17,17|37,38|45,45|56,56|58,62|72,72|75,75 Q:0,3|5,16|18,36|39,44|46,55|57,57|63,71|73,74|76,101 HHTS?HHHHHHHHHHTT?TTEEEEEETTEEEEEETTT??EEEEEE?SSHHHHHHHS-S-?-??SSEEEEEES?TT?EEEETTEEEEEGGGHHHHHHHHHHTE 2CZR|A PF15518.1_L_protein_N_seed 11 183 !Q:0,1|15,16|46,49|52,53|62,62|66,66|70,77|95,95|121,122|131,131|135,136|140,141|148,148|150,157|174,174|180,182 Q:2,14|17,45|50,51|54,61|63,65|67,69|78,94|96,120|123,130|132,134|137,139|142,147|149,149|158,173|175,179 ??HHHHHHHHHHHHH??SHHHHHHHHHHHHHHHHHHHHHHHHHHHT????SS??HHHHHHHH?TTS?TTT????????SEEEEETTEEEEEEEEE?SSSHHHHHHHHHHHHHHHHHHHHHT??EEEEEEEE?TTT??EEE??HHHHHH?S????????HHHHHHHHHHHHHTTT?HHHHT??? 2XI7|A PF15525.1_DUF4652_seed 7 208 !Q:0,38|41,45|51,54|57,59|63,65|68,68|85,85|89,90|108,109|113,113|139,139|141,141|152,152|159,160|162,162|177,181|194,196|206,207 Q:39,40|46,50|55,56|60,62|66,67|69,84|86,88|91,107|110,112|114,138|140,140|142,151|153,158|161,161|163,176|182,193|197,205 ?????????????????????????????---???????EE?----EEEEE--??SS???SSB???EE?TTSSEEEEEESSTTTT?SSS??EEEEEETTTTEEEEEEE??SSS?EEEEEEEESSSSEEEEEEEESSSSS?S?BEEEEEETTT?EEEEEE??S?TTEEEEEEEEETTE-----EEEEEEEESSTT???EEEEEEEEE?? 4L1N|A PF15612.1_WHIM1_seed 36 66 !Q:1,1|5,5|14,26|30,30|46,46|48,48|51,51|64,64 Q:0,0|2,4|6,13|27,29|31,45|47,47|49,50|52,63|65,65 S?GGG?HHHHHSTT-------------TTS?HHHHHHHHHHHHHHH-T-TT?TTHHHHHHHHHT?S 2Y9Z|B PF15630.1_CENP-S_seed 46 103 !Q:13,13|18,19|21,21|24,27|31,31|33,35|37,37|42,47|58,61|64,64|67,67|80,80|83,83|85,85|96,96|98,100 Q:0,12|14,17|20,20|22,23|28,30|32,32|36,36|38,41|48,57|62,63|65,66|68,79|81,82|84,84|86,95|97,97|101,102 HHHHHHHHHHHHH-HHHH--H-HH----HHT?E---E?HHHH------HHHHHHHHHH----HH-HH-HHHHHHHHHHTT?SE-E?HHHHHHHTTT?H---HH 1TAF|A PF15644.1_Tox-PL_seed 46 178 !Q:1,2|15,16|19,20|22,25|39,41|43,43|50,51|54,55|58,58|62,79|83,103|115,115|118,118|127,149|157,158|161,161|164,165 Q:0,0|3,14|17,18|21,21|26,38|42,42|44,49|52,53|56,57|59,61|80,82|104,114|116,117|119,126|150,156|159,160|162,163|166,177 S??HHHHHHHHHHHT--TS??B????GGGGGGTGGGTTT---T?HHHHTS??EE??TT?BHH------------------HHH---------------------HHHHHHHHHHS?TT?EEEEEETT-----------------------TTEEEEE--EE?SS-?EEEEBTTTTBSS 3W30|A PF15645.1_Tox-PLDMTX_seed 14 175 !Q:2,2|5,5|19,19|23,25|36,41|43,43|47,49|51,51|54,54|83,98|101,102|104,104|114,114|116,118|123,127|137,139|148,148|151,156|161,162|165,165|169,171 Q:0,1|3,4|6,18|20,22|26,35|42,42|44,46|50,50|52,53|55,82|99,100|103,103|105,113|115,115|119,122|128,136|140,147|149,150|157,160|163,164|166,168|172,174 HS?TT?HHHHHHHHHHHHH-HTT?--EEEEEEEEEE------E-SST---T?SS?EEEEEEEEEETTEEEEEETTGGGGTTTT?---------------TT??S?EEEEHHHHH-H---HHHH?????EEEEEEESS---HHHHHHHT?SS??---?GGGS??TT?EES???HHH 2EC5|A