{"text_format":"3","workbook":"xlsb","n_sheets":1,"sheets":["TableS8"],"not_rendered":{"defined_names":1},"read":"bin_record_odd","date_system":"1904","formulas":"cached_only","passed_over":{"ids":[37,38,1024],"n":0}}

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["table S8. Panel of 216 non-pancreatic cell lines, with sensitivity to metabolic inhibitors Oxamate, BPTES, BSO and (S)-4-CPG, and log2 (RPKM+1) values for the pan-cancer EMT signature, VIM, ENO2, and lipid genes MVD, HMGCS1, FDFT1, DCHR7, and DGAT "]
[]
["Cell Line","Tissue Origin","Oxamate IC50 (uM)","Oxamate Classifer","Included in gene set enrichment for Oxamate (Fig. S13)","BPTES IC50 (uM)","BPTES Classifer","Included in gene set enrichment for BPTES (Fig. 4B)","BSO IC50 (uM)","S-4-CPG IC50 (uM)","VIM Log2 (RPKM +1)","VIM Quartlie ","VIM Classifier","EMT Signature","EMT Quartile","EMT Classifier","ENO2 (log2 RPKM+1)","HMGCS1 (log2 RPKM+1)","FDFT1(log2 RPKM+1)","DHCR7(log2 RPKM+1)","DGAT1(log2 RPKM+1)","Avg lipid(log2 RPKM+1)","ENO2/Lipid Ave","ENO2/Lipid Ave Quartile","Eno/Lipid Classifier"]
["105KC","Cartilage",{"v":182.2415574,"d":"182.2"},"Sensitive","yes",{"v":3.17208371,"d":"3.2"},"Sensitive","yes",62.5,{"v":15.625,"d":"15.6"},{"v":11.284026171064758,"d":"11.28"},4,"High",{"v":3.16001090627249,"d":"3.16"},3,"Mid",{"v":6.51947103,"d":"6.52"},{"v":4.250007075,"d":"4.25"},{"v":6.339195274,"d":"6.34"},{"v":5.345059771,"d":"5.35"},{"v":3.248448356,"d":"3.25"},{"v":4.807418406,"d":"4.81"},{"v":1.712052624,"d":"1.71"},4,"High"]
["143B","Bone",{"v":336.9481987,"d":"336.9"},"Sensitive","yes",{"v":3.667562552,"d":"3.7"},"Sensitive","yes",62.5,{"$error":"#N/A"},{"v":10.354301552923793,"d":"10.35"},3,"Mid",{"v":3.0744685591486,"d":"3.07"},3,"Mid",{"v":3.349944824,"d":"3.35"},{"v":4.136760783,"d":"4.14"},{"v":5.801168152,"d":"5.80"},{"v":5.139032326,"d":"5.14"},{"v":3.243942981,"d":"3.24"},{"v":4.418877811,"d":"4.42"},{"v":-1.068932987,"d":"-1.07"},2,"Mid"]
["23132/87","Stomach",5000,"Resistant","yes",{"v":25,"d":"25.0"},"Resistant","yes",2000,500,{"v":1.0079102676040548,"d":"1.01"},1,"Low",{"v":0.390851743099655,"d":"0.39"},1,"Low",{"v":3.138979461,"d":"3.14"},{"v":6.61259047,"d":"6.61"},{"v":7.936805069,"d":"7.94"},{"v":6.469090153,"d":"6.47"},{"v":5.872173346,"d":"5.87"},{"v":6.464101866,"d":"6.46"},{"v":-3.325122404,"d":"-3.33"},1,"Low"]
["501A","Skin",{"v":1877.5470769999997,"d":"1877.5"},"Intermediate","no",{"v":17.06176186,"d":"17.1"},"Intermediate","no",2000,500,{"v":9.341877042652596,"d":"9.34"},3,"Mid",{"v":1.67281231371529,"d":"1.67"},2,"Mid",{"v":7.223584827,"d":"7.22"},{"v":5.122660388,"d":"5.12"},{"v":6.531542947,"d":"6.53"},{"v":5.516922766,"d":"5.52"},{"v":3.313849097,"d":"3.31"},{"v":4.817552931,"d":"4.82"},{"v":2.406031896,"d":"2.41"},4,"High"]
["537 MEL","Skin",{"v":1595.2767489999999,"d":"1595.3"},"Intermediate","no",{"v":9.373805628,"d":"9.4"},"Sensitive","yes",2000,500,{"v":11.569264361006324,"d":"11.57"},4,"High",{"v":3.82981430541101,"d":"3.83"},4,"High",{"v":3.240729736,"d":"3.24"},{"v":5.266600625,"d":"5.27"},{"v":8.065863193,"d":"8.07"},{"v":6.342842188,"d":"6.34"},{"v":3.562440884,"d":"3.56"},{"v":5.577719677,"d":"5.58"},{"v":-2.336989942,"d":"-2.34"},1,"Low"]
["59M","Ovary",{"v":156.25,"d":"156.3"},"Sensitive","yes",{"v":3.973346001,"d":"4.0"},"Sensitive","yes",62.5,500,{"v":11.651478856365072,"d":"11.65"},4,"High",{"v":3.74063849415635,"d":"3.74"},4,"High",{"v":5.34911306,"d":"5.35"},{"v":5.482969223,"d":"5.48"},{"v":6.140463436,"d":"6.14"},{"v":4.075554851,"d":"4.08"},{"v":3.342913131,"d":"3.34"},{"v":4.351934593,"d":"4.35"},{"v":0.997178467,"d":"1.00"},4,"High"]
["769-P","Kidney",{"v":1256.445073,"d":"1256.4"},"Intermediate","no",{"v":7.18962163,"d":"7.2"},"Sensitive","yes",{"$error":"#N/A"},{"v":265.4505765,"d":"265.5"},{"v":10.28879259996337,"d":"10.29"},3,"Mid",{"v":0.969759536000215,"d":"0.97"},2,"Mid",{"v":4.691355309,"d":"4.69"},{"v":4.632373809,"d":"4.63"},{"v":5.338818218,"d":"5.34"},{"v":5.190167571,"d":"5.19"},{"v":3.344458022,"d":"3.34"},{"v":4.671041375,"d":"4.67"},{"v":0.020313934,"d":"0.02"},3,"Mid"]
["786-O","Kidney",{"v":375.23694980000005,"d":"375.2"},"Sensitive","yes",{"v":2.061541433,"d":"2.1"},"Sensitive","yes",62.5,{"v":22.91902299,"d":"22.9"},{"v":10.969122683279268,"d":"10.97"},4,"High",{"v":1.98133125980842,"d":"1.98"},3,"Mid",{"v":4.561880473,"d":"4.56"},{"v":6.170887352,"d":"6.17"},{"v":5.716900512,"d":"5.72"},{"v":5.801725791,"d":"5.80"},{"v":3.218512287,"d":"3.22"},{"v":5.302877471,"d":"5.30"},{"v":-0.740996998,"d":"-0.74"},2,"Mid"]
["A-498","Kidney",{"v":1896.3716319999999,"d":"1896.4"},"Intermediate","no",{"$error":"#N/A"},"Resistant","yes",62.5,500,{"v":10.389138726584562,"d":"10.39"},3,"Mid",{"v":2.98254614855132,"d":"2.98"},3,"Mid",{"v":1.771369996,"d":"1.77"},{"v":5.162365524,"d":"5.16"},{"v":5.35164367,"d":"5.35"},{"v":4.096600931,"d":"4.10"},{"v":3.335542159,"d":"3.34"},{"v":4.51849785,"d":"4.52"},{"v":-2.747127854,"d":"-2.75"},1,"Low"]
["A-673","Skeletal Muscle",{"v":676.5885919000001,"d":"676.6"},"Sensitive","yes",{"$error":"#N/A"},"Resistant","yes",62.5,{"$error":"#N/A"},{"v":10.047997680366825,"d":"10.05"},3,"Mid",{"v":3.45439289844289,"d":"3.45"},3,"Mid",{"v":6.076140316,"d":"6.08"},{"v":5.180525459,"d":"5.18"},{"v":6.746908645,"d":"6.75"},{"v":6.649445312,"d":"6.65"},{"v":4.353982459,"d":"4.35"},{"v":5.655144858,"d":"5.66"},{"v":0.420995458,"d":"0.42"},3,"Mid"]
["A172","Brain",{"v":1647.4262589999998,"d":"1647.4"},"Intermediate","no",{"v":3.412346516,"d":"3.4"},"Sensitive","yes",{"$error":"#N/A"},{"v":126.7787603,"d":"126.8"},{"v":10.909674539226694,"d":"10.91"},4,"High",{"v":5.71429921001302,"d":"5.71"},4,"High",{"v":4.880137209,"d":"4.88"},{"v":3.87080884,"d":"3.87"},{"v":5.817302827,"d":"5.82"},{"v":5.526524117,"d":"5.53"},{"v":2.917868223,"d":"2.92"},{"v":4.677146248,"d":"4.68"},{"v":0.202990961,"d":"0.20"},3,"Mid"]
["A2780","Ovary",{"v":4890.931297,"d":"4890.9"},"Resistant","yes",{"v":25,"d":"25.0"},"Resistant","yes",62.5,{"v":65.44684603,"d":"65.4"},{"v":10.623433421338722,"d":"10.62"},3,"Mid",{"v":2.51119826886931,"d":"2.51"},3,"Mid",{"v":2.292146533,"d":"2.29"},{"v":4.637433183,"d":"4.64"},{"v":6.159441018,"d":"6.16"},{"v":4.116561701,"d":"4.12"},{"v":2.499816254,"d":"2.50"},{"v":4.074453784,"d":"4.07"},{"v":-1.782307251,"d":"-1.78"},2,"Mid"]
["A549","Lung",{"v":1762.0018199999997,"d":"1762.0"},"Intermediate","no",{"v":3.541764503,"d":"3.5"},"Sensitive","yes",62.5,{"v":223.8407026,"d":"223.8"},{"v":8.592291312352188,"d":"8.59"},2,"Mid",{"v":1.52668699787085,"d":"1.53"},2,"Mid",{"v":5.049175632,"d":"5.05"},{"v":5.49971316,"d":"5.50"},{"v":6.041407376,"d":"6.04"},{"v":4.81883885,"d":"4.82"},{"v":3.392434411,"d":"3.39"},{"v":4.563929158,"d":"4.56"},{"v":0.485246474,"d":"0.49"},3,"Mid"]
["AGS","Stomach",{"v":341.52844960000004,"d":"341.5"},"Sensitive","yes",{"$error":"#N/A"},"Resistant","yes",{"$error":"#N/A"},{"$error":"#N/A"},{"v":2.9809783488563926,"d":"2.98"},2,"Mid",{"v":0.172581107098583,"d":"0.17"},1,"Low",{"v":0.090166792,"d":"0.09"},{"v":5.487840079,"d":"5.49"},{"v":6.411515871,"d":"6.41"},{"v":5.552805849,"d":"5.55"},{"v":3.188898138,"d":"3.19"},{"v":4.94230405,"d":"4.94"},{"v":-4.852137257,"d":"-4.85"},1,"Low"]
["ATRFLOX","Colon",{"v":748.0091353,"d":"748.0"},"Sensitive","yes",{"v":9.300741318,"d":"9.3"},"Sensitive","yes",62.5,500,{"v":0.5844544943193374,"d":"0.58"},1,"Low",{"v":0.514358730001045,"d":"0.51"},1,"Low",{"v":4.858887616,"d":"4.86"},{"v":4.725260286,"d":"4.73"},{"v":6.434697817,"d":"6.43"},{"v":5.760704802,"d":"5.76"},{"v":4.218209159,"d":"4.22"},{"v":5.311990712,"d":"5.31"},{"v":-0.453103097,"d":"-0.45"},3,"Mid"]
["BFTC-909","Kidney",{"v":858.903909,"d":"858.9"},"Sensitive","yes",{"v":3.452886001,"d":"3.5"},"Sensitive","yes",62.5,{"v":482.9305556,"d":"482.9"},{"v":11.653460787980396,"d":"11.65"},4,"High",{"v":5.05940389558065,"d":"5.06"},4,"High",{"v":4.421611158,"d":"4.42"},{"v":3.652182258,"d":"3.65"},{"v":4.987496444,"d":"4.99"},{"v":5.029656619,"d":"5.03"},{"v":3.390661211,"d":"3.39"},{"v":4.412294384,"d":"4.41"},{"v":0.009316774,"d":"0.01"},3,"Mid"]
["BHY","Oral Cavity",{"v":2506.655947,"d":"2506.7"},"Resistant","yes",{"v":9.302403397,"d":"9.3"},"Sensitive","yes",{"v":643.9775702,"d":"644.0"},500,{"v":7.4761470353722626,"d":"7.48"},2,"Mid",{"v":1.48469656910287,"d":"1.48"},2,"Mid",{"v":3.055398612,"d":"3.06"},{"v":9.003579257,"d":"9.00"},{"v":7.421643629,"d":"7.42"},{"v":9.45490544,"d":"9.45"},{"v":3.967280648,"d":"3.97"},{"v":7.063375301,"d":"7.06"},{"v":-4.007976689,"d":"-4.01"},1,"Low"]
["BICR 22","Tongue",{"v":776.1545197,"d":"776.2"},"Sensitive","yes",{"v":3.948886661,"d":"3.9"},"Sensitive","yes",2000,500,{"v":4.400685241151161,"d":"4.40"},2,"Mid",{"v":0.607951982626654,"d":"0.61"},1,"Low",{"v":4.729811794,"d":"4.73"},{"v":5.773749258,"d":"5.77"},{"v":6.410042514,"d":"6.41"},{"v":8.104510699,"d":"8.10"},{"v":4.082948035,"d":"4.08"},{"v":6.003472126,"d":"6.00"},{"v":-1.273660332,"d":"-1.27"},2,"Mid"]
["C-33 A","Cervix",{"v":2824.315621,"d":"2824.3"},"Resistant","yes",{"v":13.35544726,"d":"13.4"},"Intermediate","no",62.5,{"v":87.36919797,"d":"87.4"},{"v":6.3770229298181365,"d":"6.38"},2,"Mid",{"v":1.48571455260414,"d":"1.49"},2,"Mid",{"v":2.442943048,"d":"2.44"},{"v":4.384808089,"d":"4.38"},{"v":6.870188625,"d":"6.87"},{"v":5.946894556,"d":"5.95"},{"v":3.428573703,"d":"3.43"},{"v":5.128157895,"d":"5.13"},{"v":-2.685214847,"d":"-2.69"},1,"Low"]
["C170","Colon",{"v":2369.2932629999996,"d":"2369.3"},"Intermediate","no",{"v":16.02030566,"d":"16.0"},"Intermediate","no",{"$error":"#N/A"},{"v":305.4954836,"d":"305.5"},{"v":0.5858097891364857,"d":"0.59"},1,"Low",{"v":0.244112428461091,"d":"0.24"},1,"Low",{"v":3.433289379,"d":"3.43"},{"v":4.17384906,"d":"4.17"},{"v":6.450064745,"d":"6.45"},{"v":5.125556623,"d":"5.13"},{"v":4.121976797,"d":"4.12"},{"v":4.673215174,"d":"4.67"},{"v":-1.239925795,"d":"-1.24"},2,"Mid"]
["C2BBe1","Colon",{"v":1974.9046,"d":"1974.9"},"Intermediate","no",{"v":25,"d":"25.0"},"Resistant","yes",2000,500,{"v":0.8019130309835157,"d":"0.80"},1,"Low",{"v":1.14302702138564,"d":"1.14"},2,"Mid",{"v":2.679143718,"d":"2.68"},{"v":6.663246914,"d":"6.66"},{"v":6.339130588,"d":"6.34"},{"v":7.60764216,"d":"7.61"},{"v":4.908486518,"d":"4.91"},{"v":6.337603097,"d":"6.34"},{"v":-3.658459379,"d":"-3.66"},1,"Low"]
["C32TG","Skin",{"v":3095.9662359999998,"d":"3096.0"},"Resistant","yes",{"v":6.758654282,"d":"6.8"},"Sensitive","yes",{"v":1541.088247,"d":"1541.1"},500,{"v":11.369095812551972,"d":"11.37"},4,"High",{"v":4.47447970332465,"d":"4.47"},4,"High",{"v":4.60341493,"d":"4.60"},{"v":4.410073442,"d":"4.41"},{"v":6.197748884,"d":"6.20"},{"v":3.891503316,"d":"3.89"},{"v":3.862934443,"d":"3.86"},{"v":4.483410032,"d":"4.48"},{"v":0.120004898,"d":"0.12"},3,"Mid"]
["Ca Ski","Cervix",{"v":2202.100594,"d":"2202.1"},"Intermediate","no",{"v":8.815359097,"d":"8.8"},"Sensitive","yes",2000,500,{"v":8.717219335816864,"d":"8.72"},2,"Mid",{"v":0.955288236851922,"d":"0.96"},2,"Mid",{"v":2.343025162,"d":"2.34"},{"v":5.489721072,"d":"5.49"},{"v":5.317724842,"d":"5.32"},{"v":5.652417589,"d":"5.65"},{"v":3.870384016,"d":"3.87"},{"v":5.049710872,"d":"5.05"},{"v":-2.70668571,"d":"-2.71"},1,"Low"]
["Caki-1","Kidney",{"v":1136.934434,"d":"1136.9"},"Intermediate","no",{"v":0.808667163,"d":"0.8"},"Sensitive","yes",62.5,{"v":18.98577405,"d":"19.0"},{"v":10.627808915118193,"d":"10.63"},4,"High",{"v":3.74626396765037,"d":"3.75"},4,"High",{"v":5.160870892,"d":"5.16"},{"v":3.681812455,"d":"3.68"},{"v":4.875527572,"d":"4.88"},{"v":5.323838473,"d":"5.32"},{"v":2.8579462,"d":"2.86"},{"v":4.177157046,"d":"4.18"},{"v":0.983713847,"d":"0.98"},4,"High"]
["Caki-2","Kidney",{"v":1412.083799,"d":"1412.1"},"Intermediate","no",{"v":5.498856165,"d":"5.5"},"Sensitive","yes",62.5,500,{"v":10.676375799142289,"d":"10.68"},4,"High",{"v":2.0934505537767,"d":"2.09"},3,"Mid",{"v":6.331676147,"d":"6.33"},{"v":4.979303615,"d":"4.98"},{"v":5.270205832,"d":"5.27"},{"v":4.100387804,"d":"4.10"},{"v":2.929764141,"d":"2.93"},{"v":4.327603719,"d":"4.33"},{"v":2.004072429,"d":"2.00"},4,"High"]
["CAL 27","Tongue",{"v":497.0527914,"d":"497.1"},"Sensitive","yes",{"v":1.589452392,"d":"1.6"},"Sensitive","yes",62.5,{"v":15.625,"d":"15.6"},{"v":0.6894029609639215,"d":"0.69"},1,"Low",{"v":1.57447222967992,"d":"1.57"},2,"Mid",{"v":2.925152135,"d":"2.93"},{"v":5.497784829,"d":"5.50"},{"v":6.32519822,"d":"6.33"},{"v":6.65034651,"d":"6.65"},{"v":2.968455266,"d":"2.97"},{"v":5.280827727,"d":"5.28"},{"v":-2.355675593,"d":"-2.36"},1,"Low"]
["CAL 54",{"$error":"#N/A"},{"$error":"#N/A"},{"$error":"#N/A"},"no",{"v":0.78125,"d":"0.8"},"Sensitive","yes",62.5,{"v":15.625,"d":"15.6"},{"v":10.658093832149031,"d":"10.66"},4,"High",{"v":2.19613107660146,"d":"2.20"},3,"Mid",{"v":5.274612921,"d":"5.27"},{"v":3.587094254,"d":"3.59"},{"v":5.511043772,"d":"5.51"},{"v":4.743666107,"d":"4.74"},{"v":3.077885093,"d":"3.08"},{"v":4.240597233,"d":"4.24"},{"v":1.034015688,"d":"1.03"},4,"High"]
["CAMA-1","Breast",5000,"Resistant","yes",{"v":25,"d":"25.0"},"Resistant","yes",2000,500,{"v":1.0738989972067776,"d":"1.07"},1,"Low",{"v":1.21845103887606,"d":"1.22"},2,"Mid",{"v":1.337511001,"d":"1.34"},{"v":4.721529822,"d":"4.72"},{"v":5.215493061,"d":"5.22"},{"v":3.498994813,"d":"3.50"},{"v":3.787772566,"d":"3.79"},{"v":4.185532901,"d":"4.19"},{"v":-2.848021901,"d":"-2.85"},1,"Low"]
["CaR-1","Colon",{"v":2582.568869,"d":"2582.6"},"Resistant","yes",{"v":11.9025213,"d":"11.9"},"Intermediate","no",2000,500,{"v":4.075083714802518,"d":"4.08"},2,"Mid",{"v":0.417547623873962,"d":"0.42"},1,"Low",{"v":3.583438152,"d":"3.58"},{"v":6.019281904,"d":"6.02"},{"v":7.119294221,"d":"7.12"},{"v":5.87028036,"d":"5.87"},{"v":4.26007508,"d":"4.26"},{"v":5.676904429,"d":"5.68"},{"v":-2.093466278,"d":"-2.09"},1,"Low"]
["ChaGo-K-1","Lung",{"v":2014.4632900000001,"d":"2014.5"},"Intermediate","no",{"v":25,"d":"25.0"},"Resistant","yes",2000,500,{"v":0.5747944721265401,"d":"0.57"},1,"Low",{"v":0.518107990510921,"d":"0.52"},1,"Low",{"v":3.752248742,"d":"3.75"},{"v":7.015690362,"d":"7.02"},{"v":5.807805436,"d":"5.81"},{"v":5.747032084,"d":"5.75"},{"v":4.135427605,"d":"4.14"},{"v":5.699089532,"d":"5.70"},{"v":-1.94684079,"d":"-1.95"},1,"Low"]
["CHL-1","Skin",{"v":948.6842982000001,"d":"948.7"},"Sensitive","yes",{"$error":"#N/A"},"Resistant","yes",62.5,{"v":192.9497391,"d":"192.9"},{"v":8.095148764369329,"d":"8.10"},2,"Mid",{"v":2.92249317247849,"d":"2.92"},3,"Mid",{"v":3.15172064,"d":"3.15"},{"v":5.45343599,"d":"5.45"},{"v":6.978646289,"d":"6.98"},{"v":6.361341443,"d":"6.36"},{"v":4.057641509,"d":"4.06"},{"v":5.674000234,"d":"5.67"},{"v":-2.522279594,"d":"-2.52"},1,"Low"]
["CHP-212","Brain",{"v":2114.320108,"d":"2114.3"},"Intermediate","no",{"v":7.299474019,"d":"7.3"},"Sensitive","yes",2000,500,{"v":10.38967219951261,"d":"10.39"},3,"Mid",{"v":3.4250616456797,"d":"3.43"},3,"Mid",{"v":3.670140609,"d":"3.67"},{"v":5.093317252,"d":"5.09"},{"v":5.994155128,"d":"5.99"},{"v":4.949356655,"d":"4.95"},{"v":2.700356557,"d":"2.70"},{"v":4.400222509,"d":"4.40"},{"v":-0.7300819,"d":"-0.73"},2,"Mid"]
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