motif GOID GO description S. carpocapsae GO p-value No. of carpocapsae genes No. of carpocapsae genes that are 1:1 orthologs C. elegans GO p-value No. of C. elegans genes No. of C. elegans genes that are 1:1 orthologs No. of shared orthologs Percentage of shared orthologs in C. elegans (%) (shared/No. of elegans 1:1) 5 GO:0034330 cell junction organization 1.04E-05 20 20 3.66E-06 12 11 9 81.81818182 5 GO:0034329 cell junction assembly 2.07E-04 15 15 7.24E-06 11 10 8 80 5 GO:0045216 cell-cell junction organization 1.09E-03 12 12 1.37E-03 6 5 4 80 5 GO:0048786 presynaptic active zone 3.24E-04 8 6 2.88E-03 6 5 4 80 5 GO:0007271 "synaptic transmission, cholinergic" 1.19E-04 13 8 2.07E-04 10 8 6 75 5 GO:0030155 regulation of cell adhesion 2.23E-05 16 10 4.36E-04 7 4 3 75 5 GO:0051015 actin filament binding 1.06E-03 11 7 7.76E-04 9 4 3 75 5 GO:0050769 positive regulation of neurogenesis 2.31E-05 14 10 3.20E-04 6 6 4 66.66666667 31 GO:0045216 cell-cell junction organization 1.82E-04 9 9 4.96E-04 7 6 4 66.66666667 41 GO:0048786 presynaptic active zone 2.82E-05 7 5 1.47E-03 7 6 4 66.66666667 5 GO:0051962 positive regulation of nervous system development 2.21E-06 18 12 2.64E-06 9 8 5 62.5 5 GO:0008356 asymmetric cell division 5.91E-07 14 11 3.51E-05 12 8 5 62.5 5 GO:0005912 adherens junction 5.65E-05 19 13 3.75E-04 10 5 3 60 5 GO:0070161 anchoring junction 7.76E-05 19 13 6.44E-04 10 5 3 60 5 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway 6.90E-05 6 6 1.88E-03 7 5 3 60 5 GO:0038032 termination of G-protein coupled receptor signaling pathway 6.90E-05 6 6 1.88E-03 7 5 3 60 5 GO:0023021 termination of signal transduction 1.17E-05 7 6 1.88E-03 7 5 3 60 11 GO:0005913 cell-cell adherens junction 1.75E-04 5 4 1.30E-04 9 5 3 60 14 GO:0033563 dorsal/ventral axon guidance 1.47E-05 7 5 1.04E-03 5 5 3 60 18 GO:0007044 cell-substrate junction assembly 2.87E-05 8 8 1.09E-03 5 5 3 60 18 GO:0031581 hemidesmosome assembly 5.27E-04 6 6 1.09E-03 5 5 3 60 37 GO:0033058 directional locomotion 5.99E-04 7 5 2.67E-03 10 5 3 60 5 GO:0007369 gastrulation 4.96E-05 39 20 6.98E-05 18 12 7 58.33333333 5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway 1.60E-04 8 8 5.82E-04 9 7 4 57.14285714 14 GO:0040017 positive regulation of locomotion 3.53E-04 19 15 4.59E-04 9 7 4 57.14285714 31 GO:0070161 anchoring junction 1.81E-07 16 12 1.05E-07 16 9 5 55.55555556 31 GO:0005912 adherens junction 1.33E-07 16 12 1.98E-06 14 9 5 55.55555556 31 GO:0034330 cell junction organization 6.30E-07 15 15 2.16E-05 12 11 6 54.54545455 18 GO:0001708 cell fate specification 4.78E-11 31 24 1.40E-08 30 24 13 54.16666667 5 GO:0045138 nematode male tail tip morphogenesis 1.90E-05 18 15 7.01E-08 24 16 8 50 5 GO:0050767 regulation of neurogenesis 6.36E-08 33 24 1.24E-05 17 16 8 50 5 GO:0010720 positive regulation of cell development 1.44E-05 16 10 5.28E-05 8 8 4 50 5 GO:0045597 positive regulation of cell differentiation 5.60E-07 26 15 7.47E-05 10 10 5 50 5 GO:0031252 cell leading edge 1.06E-03 17 12 1.17E-04 12 10 5 50 5 GO:0043051 regulation of pharyngeal pumping 1.49E-03 16 14 2.49E-04 14 12 6 50 5 GO:0030855 epithelial cell differentiation 1.04E-06 36 17 2.57E-04 13 8 4 50 5 GO:0060259 regulation of feeding behavior 8.26E-04 17 15 3.74E-04 14 12 6 50 5 GO:0001704 formation of primary germ layer 1.37E-06 20 12 1.42E-03 12 10 5 50 18 GO:0034329 cell junction assembly 2.67E-06 14 14 2.90E-05 9 8 4 50 18 GO:0001707 mesoderm formation 2.59E-05 9 7 3.01E-04 7 6 3 50 18 GO:0048332 mesoderm morphogenesis 8.12E-06 10 8 4.16E-04 7 6 3 50 18 GO:0045138 nematode male tail tip morphogenesis 6.70E-08 17 13 6.95E-04 14 10 5 50 18 GO:0007498 mesoderm development 1.08E-06 13 11 8.95E-04 9 8 4 50 31 GO:0030056 hemidesmosome 8.45E-04 5 2 1.61E-04 7 4 2 50 31 GO:0034329 cell junction assembly 8.50E-07 13 13 1.10E-03 9 8 4 50 31 GO:0030155 regulation of cell adhesion 3.09E-06 12 7 1.24E-03 7 4 2 50 37 GO:0008078 mesodermal cell migration 5.06E-04 6 5 8.97E-09 12 10 5 50 37 GO:0030056 hemidesmosome 2.94E-04 6 2 2.83E-04 9 4 2 50 41 GO:0050769 positive regulation of neurogenesis 2.89E-05 10 6 7.56E-06 8 8 4 50 41 GO:0045597 positive regulation of cell differentiation 3.06E-06 17 8 4.00E-04 10 10 5 50 41 GO:0009952 anterior/posterior pattern specification 2.09E-06 18 13 9.57E-04 16 10 5 50 41 GO:0030155 regulation of cell adhesion 2.26E-04 10 5 1.47E-03 7 4 2 50 5 GO:0048598 embryonic morphogenesis 6.48E-06 73 42 2.29E-07 42 25 12 48 18 GO:0043565 sequence-specific DNA binding 3.65E-20 71 56 3.49E-05 64 46 22 47.82608696 5 GO:0007631 feeding behavior 3.22E-05 28 23 6.24E-07 26 21 10 47.61904762 5 GO:0051960 regulation of nervous system development 4.68E-10 41 28 4.43E-07 21 19 9 47.36842105 5 GO:0090598 male anatomical structure morphogenesis 1.41E-05 19 15 1.99E-08 25 17 8 47.05882353 18 GO:0001071 nucleic acid binding transcription factor activity 5.59E-21 68 55 1.49E-05 69 49 23 46.93877551 18 GO:0003700 sequence-specific DNA binding transcription factor activity 2.06E-20 67 54 1.49E-05 69 49 23 46.93877551 5 GO:0030424 axon 2.83E-04 34 27 7.17E-11 40 32 15 46.875 5 GO:0043547 positive regulation of GTPase activity 6.77E-05 15 13 9.51E-06 21 15 7 46.66666667 5 GO:0045202 synapse 4.40E-09 64 48 3.80E-05 36 30 14 46.66666667 5 GO:0090066 regulation of anatomical structure size 5.69E-04 24 17 2.07E-04 18 15 7 46.66666667 41 GO:0045138 nematode male tail tip morphogenesis 5.13E-05 12 9 3.32E-05 22 15 7 46.66666667 5 GO:0009887 organ morphogenesis 1.02E-09 77 50 6.66E-07 32 28 13 46.42857143 5 GO:0007389 pattern specification process 3.36E-08 54 35 9.15E-08 34 22 10 45.45454545 18 GO:0007369 gastrulation 1.42E-03 24 17 2.05E-05 16 11 5 45.45454545 18 GO:0090598 male anatomical structure morphogenesis 3.32E-08 18 13 2.40E-04 15 11 5 45.45454545 41 GO:0001708 cell fate specification 2.34E-07 23 18 1.66E-04 31 20 9 45 5 GO:0007267 cell-cell signaling 2.41E-07 63 42 1.04E-05 36 29 13 44.82758621 5 GO:0001667 ameboidal-type cell migration 5.67E-06 26 19 1.53E-04 12 9 4 44.44444444 5 GO:0040013 negative regulation of locomotion 6.42E-04 10 9 7.76E-04 9 9 4 44.44444444 5 GO:0048863 stem cell differentiation 1.33E-03 19 14 1.32E-03 9 9 4 44.44444444 5 GO:0044456 synapse part 1.76E-06 44 32 1.43E-03 20 18 8 44.44444444 18 GO:0034330 cell junction organization 1.05E-07 18 18 1.08E-05 10 9 4 44.44444444 18 GO:0001704 formation of primary germ layer 8.95E-05 13 10 1.53E-03 10 9 4 44.44444444 37 GO:0034705 potassium channel complex 1.24E-03 7 6 2.23E-05 14 9 4 44.44444444 37 GO:0008076 voltage-gated potassium channel complex 1.24E-03 7 6 2.23E-05 14 9 4 44.44444444 41 GO:0051962 positive regulation of nervous system development 1.28E-05 12 7 1.20E-06 10 9 4 44.44444444 41 GO:0010720 positive regulation of cell development 3.11E-05 11 6 2.69E-05 9 9 4 44.44444444 5 GO:0061061 muscle structure development 9.36E-07 44 27 2.25E-03 44 25 11 44 5 GO:0001071 nucleic acid binding transcription factor activity 1.60E-21 90 66 1.11E-10 105 73 32 43.83561644 5 GO:0003700 sequence-specific DNA binding transcription factor activity 4.64E-21 89 65 1.11E-10 105 73 32 43.83561644 14 GO:0004674 protein serine/threonine kinase activity 2.31E-06 26 20 3.85E-04 27 16 7 43.75 41 GO:0090598 male anatomical structure morphogenesis 2.16E-05 13 9 1.25E-05 23 16 7 43.75 5 GO:0043565 sequence-specific DNA binding 7.44E-17 88 65 7.51E-12 103 71 31 43.66197183 5 GO:0007268 synaptic transmission 2.16E-06 44 27 4.03E-05 28 23 10 43.47826087 5 GO:0030017 sarcomere 7.62E-06 26 15 8.83E-10 29 14 6 42.85714286 5 GO:0046661 male sex differentiation 2.12E-06 24 18 2.07E-09 29 21 9 42.85714286 5 GO:0030016 myofibril 2.93E-06 28 17 1.01E-08 29 14 6 42.85714286 5 GO:0045664 regulation of neuron differentiation 2.23E-07 29 21 5.04E-05 15 14 6 42.85714286 5 GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity 4.70E-05 13 10 8.96E-04 8 7 3 42.85714286 5 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity 1.17E-03 16 9 1.21E-03 8 7 3 42.85714286 37 GO:0031346 positive regulation of cell projection organization 5.99E-04 7 4 4.84E-04 7 7 3 42.85714286 41 GO:0045666 positive regulation of neuron differentiation 8.22E-04 7 3 1.84E-05 7 7 3 42.85714286 37 GO:0001505 regulation of neurotransmitter levels 3.77E-05 18 14 3.19E-06 31 24 10 41.66666667 37 GO:0051588 regulation of neurotransmitter transport 1.26E-03 6 5 4.19E-06 14 12 5 41.66666667 37 GO:0046928 regulation of neurotransmitter secretion 1.26E-03 6 5 4.19E-06 14 12 5 41.66666667 18 GO:0006355 "regulation of transcription, DNA-templated" 7.23E-15 111 81 2.28E-05 97 70 29 41.42857143 18 GO:1903506 regulation of nucleic acid-templated transcription 7.23E-15 111 81 2.28E-05 97 70 29 41.42857143 5 GO:0042755 eating behavior 7.38E-04 22 18 2.55E-06 22 17 7 41.17647059 5 GO:0008134 transcription factor binding 3.16E-05 37 25 2.91E-06 24 17 7 41.17647059 18 GO:0045165 cell fate commitment 9.72E-11 45 33 9.38E-12 43 34 14 41.17647059 5 GO:0006351 "transcription, DNA-templated" 6.19E-08 160 105 2.70E-10 151 107 44 41.12149533 5 GO:0097659 nucleic acid-templated transcription 6.19E-08 160 105 4.17E-10 151 107 44 41.12149533 5 GO:0048522 positive regulation of cellular process 3.65E-05 148 90 8.51E-13 102 73 30 41.09589041 18 GO:2001141 regulation of RNA biosynthetic process 6.34E-14 111 81 1.68E-05 98 71 29 40.84507042 18 GO:0006351 "transcription, DNA-templated" 1.73E-12 122 87 4.17E-05 100 71 29 40.84507042 18 GO:0097659 nucleic acid-templated transcription 1.73E-12 122 87 5.27E-05 100 71 29 40.84507042 5 GO:0032774 RNA biosynthetic process 9.88E-08 162 105 5.27E-10 152 108 44 40.74074074 5 GO:0006355 "regulation of transcription, DNA-templated" 2.97E-12 150 100 9.49E-12 150 106 43 40.56603774 5 GO:1903506 regulation of nucleic acid-templated transcription 2.97E-12 150 100 9.49E-12 150 106 43 40.56603774 5 GO:0051252 regulation of RNA metabolic process 1.84E-10 155 103 5.62E-12 153 109 44 40.36697248 18 GO:0051252 regulation of RNA metabolic process 3.58E-13 114 83 1.07E-05 100 72 29 40.27777778 18 GO:2000112 regulation of cellular macromolecule biosynthetic process 1.28E-12 115 85 4.27E-05 103 72 29 40.27777778 18 GO:0032774 RNA biosynthetic process 8.12E-12 122 87 5.18E-05 101 72 29 40.27777778 5 GO:2001141 regulation of RNA biosynthetic process 3.60E-11 150 100 7.15E-12 151 107 43 40.18691589 5 GO:0019438 aromatic compound biosynthetic process 3.15E-08 193 123 3.52E-08 166 117 47 40.17094017 5 GO:1901362 organic cyclic compound biosynthetic process 2.36E-07 195 125 3.13E-07 166 117 47 40.17094017 4 GO:0034330 cell junction organization 5.97E-06 10 10 4.80E-06 11 10 4 40 4 GO:0032589 neuron projection membrane 8.30E-04 5 3 2.79E-04 8 5 2 40 5 GO:0040012 regulation of locomotion 8.41E-10 77 57 7.22E-11 47 40 16 40 5 GO:0034654 nucleobase-containing compound biosynthetic process 1.15E-08 190 121 1.57E-08 164 115 46 40 5 GO:0001709 cell fate determination 1.28E-05 18 10 2.45E-07 17 10 4 40 5 GO:0030054 cell junction 6.03E-08 61 40 1.23E-04 37 25 10 40 5 GO:0008301 "DNA binding, bending" 1.26E-03 7 5 9.60E-04 7 5 2 40 5 GO:0002064 epithelial cell development 7.54E-05 20 10 1.21E-03 8 5 2 40 18 GO:0030055 cell-substrate junction 4.77E-05 10 5 2.13E-04 7 5 2 40 18 GO:0048546 digestive tract morphogenesis 1.60E-03 9 4 1.27E-03 7 5 2 40 37 GO:0001707 mesoderm formation 1.92E-04 8 5 1.72E-03 11 10 4 40 37 GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity 9.61E-06 11 10 1.80E-03 12 10 4 40 37 GO:0048332 mesoderm morphogenesis 6.11E-05 9 6 2.78E-03 11 10 4 40 41 GO:0043051 regulation of pharyngeal pumping 9.07E-06 14 11 2.69E-06 19 15 6 40 41 GO:0060259 regulation of feeding behavior 1.51E-05 14 11 5.00E-06 19 15 6 40 41 GO:0008078 mesodermal cell migration 1.83E-03 5 4 9.58E-04 6 5 2 40 47 GO:0040034 "regulation of development, heterochronic" 2.06E-04 3 3 3.22E-06 9 5 2 40 18 GO:0010556 regulation of macromolecule biosynthetic process 2.32E-12 117 86 3.59E-05 104 73 29 39.7260274 5 GO:0018130 heterocycle biosynthetic process 8.78E-08 192 122 1.28E-07 165 116 46 39.65517241 5 GO:2000112 regulation of cellular macromolecule biosynthetic process 2.14E-11 162 108 5.06E-11 158 111 44 39.63963964 5 GO:0043005 neuron projection 1.01E-06 59 43 7.63E-15 65 53 21 39.62264151 5 GO:0019219 regulation of nucleobase-containing compound metabolic process 9.14E-10 162 108 1.77E-11 156 112 44 39.28571429 5 GO:0010556 regulation of macromolecule biosynthetic process 1.22E-11 167 111 4.82E-11 159 112 44 39.28571429 18 GO:0019219 regulation of nucleobase-containing compound metabolic process 1.10E-12 119 86 2.05E-05 102 74 29 39.18918919 5 GO:0048729 tissue morphogenesis 1.22E-07 107 68 4.89E-06 28 23 9 39.13043478 5 GO:0044271 cellular nitrogen compound biosynthetic process 1.00E-07 194 123 2.73E-08 169 118 46 38.98305085 5 GO:0051171 regulation of nitrogen compound metabolic process 4.10E-10 167 111 8.01E-12 158 113 44 38.9380531 18 GO:0060429 epithelium development 5.71E-07 80 53 1.09E-05 26 18 7 38.88888889 5 GO:0097458 neuron part 4.81E-08 73 54 1.73E-15 76 62 24 38.70967742 18 GO:0031326 regulation of cellular biosynthetic process 1.50E-12 119 87 9.86E-06 107 75 29 38.66666667 18 GO:0009889 regulation of biosynthetic process 2.24E-12 119 87 1.26E-05 107 75 29 38.66666667 5 GO:0031326 regulation of cellular biosynthetic process 2.84E-11 168 112 9.88E-12 162 114 44 38.59649123 5 GO:0009889 regulation of biosynthetic process 1.24E-11 170 113 1.56E-11 162 114 44 38.59649123 18 GO:0046661 male sex differentiation 2.45E-08 21 14 1.50E-04 17 13 5 38.46153846 31 GO:0007369 gastrulation 2.25E-04 22 14 1.34E-06 23 13 5 38.46153846 37 GO:0035262 gonad morphogenesis 1.92E-04 8 6 6.97E-05 16 13 5 38.46153846 18 GO:0051171 regulation of nitrogen compound metabolic process 1.60E-12 121 87 5.82E-06 105 76 29 38.15789474 18 GO:0034654 nucleobase-containing compound biosynthetic process 7.37E-12 138 96 5.65E-04 108 76 29 38.15789474 5 GO:0009888 tissue development 7.26E-10 148 92 8.88E-12 58 42 16 38.0952381 37 GO:0007269 neurotransmitter secretion 6.67E-05 14 11 4.21E-07 27 21 8 38.0952381 5 GO:0031323 regulation of cellular metabolic process 1.56E-08 209 136 7.19E-09 184 127 48 37.79527559 5 GO:0010468 regulation of gene expression 5.32E-09 176 115 2.19E-09 174 122 46 37.70491803 18 GO:0003677 DNA binding 3.65E-13 101 76 2.33E-04 99 69 26 37.68115942 18 GO:0019438 aromatic compound biosynthetic process 1.85E-11 140 98 9.87E-04 109 77 29 37.66233766 18 GO:0018130 heterocycle biosynthetic process 1.48E-11 141 99 1.46E-03 109 77 29 37.66233766 4 GO:0009952 anterior/posterior pattern specification 6.39E-04 9 7 2.30E-03 12 8 3 37.5 5 GO:0045165 cell fate commitment 2.54E-10 60 40 2.15E-16 59 40 15 37.5 5 GO:0050795 regulation of behavior 2.63E-06 34 29 5.20E-07 29 24 9 37.5 5 GO:0043050 pharyngeal pumping 1.03E-03 21 17 6.26E-06 21 16 6 37.5 5 GO:0005244 voltage-gated ion channel activity 2.54E-05 17 10 8.83E-06 16 8 3 37.5 5 GO:0022832 voltage-gated channel activity 2.54E-05 17 10 8.83E-06 16 8 3 37.5 5 GO:0022843 voltage-gated cation channel activity 1.35E-04 14 9 5.70E-05 13 8 3 37.5 5 GO:0060795 cell fate commitment involved in formation of primary germ layer 1.52E-03 11 7 1.66E-03 10 8 3 37.5 14 GO:0010975 regulation of neuron projection development 6.21E-04 9 7 1.81E-04 8 8 3 37.5 18 GO:0009888 tissue development 4.89E-09 99 68 5.60E-08 41 32 12 37.5 18 GO:0010468 regulation of gene expression 3.04E-11 126 90 1.35E-04 116 80 30 37.5 18 GO:0008105 asymmetric protein localization 7.33E-04 9 7 9.28E-04 10 8 3 37.5 37 GO:0045597 positive regulation of cell differentiation 7.97E-06 18 10 2.08E-05 16 16 6 37.5 37 GO:1903530 regulation of secretion by cell 8.39E-05 15 13 2.12E-04 18 16 6 37.5 5 GO:0042995 cell projection 2.09E-05 81 55 2.84E-08 80 67 25 37.31343284 5 GO:0080090 regulation of primary metabolic process 5.88E-08 200 132 3.31E-10 184 129 48 37.20930233 5 GO:0003677 DNA binding 3.08E-07 124 87 1.66E-08 148 105 39 37.14285714 31 GO:0048598 embryonic morphogenesis 3.51E-05 40 26 5.49E-07 46 27 10 37.03703704 4 GO:0001708 cell fate specification 1.84E-08 17 14 7.01E-05 25 19 7 36.84210526 41 GO:0046661 male sex differentiation 5.64E-06 16 10 7.57E-06 26 19 7 36.84210526 18 GO:0044271 cellular nitrogen compound biosynthetic process 4.33E-11 141 99 4.18E-04 113 79 29 36.70886076 5 GO:0009893 positive regulation of metabolic process 2.80E-05 103 67 5.29E-14 84 63 23 36.50793651 4 GO:0003002 regionalization 4.10E-06 16 14 3.18E-04 17 11 4 36.36363636 5 GO:0044449 contractile fiber part 7.81E-06 30 19 9.18E-09 39 22 8 36.36363636 5 GO:0007155 cell adhesion 1.07E-05 36 23 2.69E-08 30 22 8 36.36363636 5 GO:0060284 regulation of cell development 1.12E-07 37 26 3.04E-08 24 22 8 36.36363636 5 GO:0022610 biological adhesion 1.07E-05 36 23 5.23E-08 30 22 8 36.36363636 5 GO:0040017 positive regulation of locomotion 5.08E-04 40 24 3.06E-05 15 11 4 36.36363636 5 GO:0005516 calmodulin binding 5.59E-04 14 10 8.81E-05 12 11 4 36.36363636 5 GO:0035239 tube morphogenesis 1.28E-04 36 21 1.91E-04 15 11 4 36.36363636 5 GO:0005667 transcription factor complex 1.76E-03 20 15 1.51E-03 13 11 4 36.36363636 18 GO:0010628 positive regulation of gene expression 3.94E-07 49 34 2.73E-05 28 22 8 36.36363636 18 GO:0010557 positive regulation of macromolecule biosynthetic process 6.82E-07 48 34 8.60E-05 26 22 8 36.36363636 37 GO:0050769 positive regulation of neurogenesis 6.93E-04 9 6 4.06E-07 11 11 4 36.36363636 37 GO:0005249 voltage-gated potassium channel activity 1.92E-03 8 6 5.71E-07 20 11 4 36.36363636 41 GO:0007369 gastrulation 1.56E-03 21 15 2.28E-03 17 11 4 36.36363636 5 GO:0009653 anatomical structure morphogenesis 1.28E-15 302 195 2.83E-15 222 152 55 36.18421053 5 GO:0009891 positive regulation of biosynthetic process 3.11E-06 69 43 3.68E-12 48 36 13 36.11111111 5 GO:0031328 positive regulation of cellular biosynthetic process 4.79E-06 68 43 3.68E-12 48 36 13 36.11111111 5 GO:0010557 positive regulation of macromolecule biosynthetic process 7.56E-06 65 41 3.72E-12 47 36 13 36.11111111 5 GO:0044708 single-organism behavior 4.57E-08 43 27 1.40E-07 31 25 9 36 14 GO:0061564 axon development 2.05E-08 27 20 7.87E-08 32 25 9 36 5 GO:0001708 cell fate specification 2.24E-07 34 22 4.47E-11 40 28 10 35.71428571 5 GO:0007417 central nervous system development 1.38E-04 42 25 2.49E-04 14 14 5 35.71428571 18 GO:0048729 tissue morphogenesis 6.82E-06 68 47 1.52E-03 18 14 5 35.71428571 41 GO:0003002 regionalization 4.46E-08 28 20 5.24E-04 21 14 5 35.71428571 5 GO:0060255 regulation of macromolecule metabolic process 2.47E-08 214 140 2.31E-09 199 138 49 35.50724638 5 GO:0045944 positive regulation of transcription from RNA polymerase II promoter 2.10E-05 45 29 1.74E-12 41 31 11 35.48387097 5 GO:0045595 regulation of cell differentiation 2.93E-08 62 42 2.82E-07 35 31 11 35.48387097 31 GO:0043547 positive regulation of GTPase activity 9.28E-05 10 9 1.22E-04 21 17 6 35.29411765 37 GO:0001704 formation of primary germ layer 3.55E-04 12 8 2.75E-04 22 17 6 35.29411765 5 GO:0006796 phosphate-containing compound metabolic process 1.10E-04 177 110 9.81E-04 144 91 32 35.16483516 5 GO:0006793 phosphorus metabolic process 1.17E-04 179 111 1.87E-03 144 91 32 35.16483516 5 GO:0007610 behavior 4.49E-15 146 100 1.02E-23 148 111 39 35.13513514 5 GO:0051254 positive regulation of RNA metabolic process 5.33E-05 60 38 8.10E-14 48 37 13 35.13513514 37 GO:0001667 ameboidal-type cell migration 9.95E-06 19 15 1.28E-07 24 20 7 35 5 GO:0048699 generation of neurons 8.08E-16 109 75 2.17E-12 79 66 23 34.84848485 5 GO:0006928 movement of cell or subcellular component 4.50E-13 117 77 4.88E-11 95 69 24 34.7826087 5 GO:0043292 contractile fiber 1.49E-05 31 20 5.75E-09 42 23 8 34.7826087 14 GO:0007409 axonogenesis 7.77E-08 25 18 2.16E-09 27 23 8 34.7826087 37 GO:0045138 nematode male tail tip morphogenesis 2.81E-04 12 9 8.60E-09 40 23 8 34.7826087 5 GO:0030030 cell projection organization 2.84E-10 85 60 8.81E-07 60 49 17 34.69387755 5 GO:0060429 epithelium development 8.26E-08 121 74 8.24E-09 38 26 9 34.61538462 5 GO:0010648 negative regulation of cell communication 7.07E-06 41 30 4.85E-08 32 26 9 34.61538462 5 GO:0023057 negative regulation of signaling 1.44E-05 40 30 4.85E-08 32 26 9 34.61538462 37 GO:0006836 neurotransmitter transport 1.30E-04 15 12 1.28E-05 33 26 9 34.61538462 5 GO:0007411 axon guidance 2.41E-10 42 33 3.06E-08 33 29 10 34.48275862 5 GO:0097485 neuron projection guidance 3.44E-10 42 33 3.75E-08 33 29 10 34.48275862 5 GO:0030182 neuron differentiation 1.43E-14 100 69 2.35E-11 73 61 21 34.42622951 5 GO:0007409 axonogenesis 7.78E-12 56 42 1.27E-07 36 32 11 34.375 5 GO:0032879 regulation of localization 1.57E-07 76 51 4.35E-05 45 32 11 34.375 5 GO:1902680 positive regulation of RNA biosynthetic process 3.70E-05 59 37 4.23E-13 46 35 12 34.28571429 5 GO:1903508 positive regulation of nucleic acid-templated transcription 3.18E-06 59 37 8.50E-13 45 35 12 34.28571429 5 GO:0045893 "positive regulation of transcription, DNA-templated" 3.18E-06 59 37 8.50E-13 45 35 12 34.28571429 5 GO:2000026 regulation of multicellular organismal development 1.02E-08 93 64 3.69E-11 81 70 24 34.28571429 5 GO:0048812 neuron projection morphogenesis 2.99E-11 60 43 3.84E-08 39 35 12 34.28571429 5 GO:0051173 positive regulation of nitrogen compound metabolic process 2.43E-05 66 41 1.87E-13 50 38 13 34.21052632 5 GO:0045935 positive regulation of nucleobase-containing compound metabolic process 5.55E-05 63 40 2.94E-13 49 38 13 34.21052632 5 GO:0048858 cell projection morphogenesis 2.73E-08 61 44 1.03E-06 42 38 13 34.21052632 5 GO:0032990 cell part morphogenesis 7.31E-08 61 44 2.21E-06 42 38 13 34.21052632 5 GO:0005515 protein binding 2.65E-07 372 240 3.36E-12 277 196 67 34.18367347 5 GO:0010628 positive regulation of gene expression 2.25E-05 64 39 2.25E-14 52 41 14 34.14634146 5 GO:0044459 plasma membrane part 1.15E-09 97 60 4.52E-11 69 53 18 33.96226415 5 GO:0048666 neuron development 8.24E-13 82 57 5.44E-10 64 53 18 33.96226415 5 GO:0003676 nucleic acid binding 9.29E-04 186 135 3.47E-07 226 162 55 33.95061728 5 GO:0005488 binding 8.88E-05 701 457 1.83E-16 685 458 155 33.84279476 5 GO:0022008 neurogenesis 4.65E-14 117 80 1.74E-12 82 68 23 33.82352941 5 GO:0007399 nervous system development 1.03E-11 136 90 1.59E-14 95 77 26 33.76623377 5 GO:0019222 regulation of metabolic process 6.02E-10 249 165 1.11E-13 244 170 57 33.52941176 5 GO:0019098 reproductive behavior 1.15E-07 85 60 2.64E-16 105 75 25 33.33333333 5 GO:0044705 multi-organism reproductive behavior 8.54E-08 85 60 2.64E-16 105 75 25 33.33333333 5 GO:0051705 multi-organism behavior 3.45E-08 88 60 4.04E-16 105 75 25 33.33333333 5 GO:0031175 neuron projection development 2.83E-12 71 51 3.79E-08 56 45 15 33.33333333 5 GO:2000241 regulation of reproductive process 9.49E-04 20 15 4.54E-08 25 21 7 33.33333333 5 GO:0004674 protein serine/threonine kinase activity 1.55E-03 44 31 2.58E-07 54 39 13 33.33333333 5 GO:0031672 A band 2.05E-03 12 9 8.37E-06 12 6 2 33.33333333 5 GO:0003002 regionalization 3.51E-07 40 24 9.74E-05 20 12 4 33.33333333 5 GO:0034765 regulation of ion transmembrane transport 3.96E-05 10 6 2.40E-04 11 6 2 33.33333333 5 GO:0034762 regulation of transmembrane transport 3.96E-05 10 6 2.40E-04 11 6 2 33.33333333 5 GO:0007163 establishment or maintenance of cell polarity 6.04E-04 25 15 2.53E-04 20 12 4 33.33333333 5 GO:0040034 "regulation of development, heterochronic" 6.30E-04 6 5 3.18E-04 8 6 2 33.33333333 5 GO:0009952 anterior/posterior pattern specification 3.47E-05 24 14 3.44E-04 15 9 3 33.33333333 5 GO:0007420 brain development 3.85E-05 34 20 4.11E-04 12 12 4 33.33333333 5 GO:0060322 head development 2.27E-05 35 21 5.15E-04 12 12 4 33.33333333 5 GO:0022803 passive transmembrane transporter activity 7.96E-05 63 46 7.13E-04 49 30 10 33.33333333 5 GO:0015267 channel activity 7.96E-05 63 46 7.13E-04 49 30 10 33.33333333 11 GO:0014016 neuroblast differentiation 1.15E-03 3 3 6.91E-05 7 6 2 33.33333333 14 GO:0048667 cell morphogenesis involved in neuron differentiation 1.04E-06 25 18 1.73E-09 28 24 8 33.33333333 14 GO:0048812 neuron projection morphogenesis 2.88E-07 26 19 3.02E-09 28 24 8 33.33333333 14 GO:0031175 neuron projection development 1.02E-08 32 24 1.44E-07 35 27 9 33.33333333 14 GO:0045664 regulation of neuron differentiation 5.66E-05 13 11 5.43E-07 13 12 4 33.33333333 14 GO:0048675 axon extension 4.77E-04 8 5 2.60E-06 11 9 3 33.33333333 14 GO:1990138 neuron projection extension 6.86E-04 8 5 2.60E-06 11 9 3 33.33333333 14 GO:0008105 asymmetric protein localization 6.22E-05 8 6 1.21E-03 8 6 2 33.33333333 18 GO:0045944 positive regulation of transcription from RNA polymerase II promoter 2.61E-06 34 26 2.95E-06 25 21 7 33.33333333 18 GO:0009891 positive regulation of biosynthetic process 5.89E-07 50 35 7.96E-06 29 24 8 33.33333333 18 GO:0031328 positive regulation of cellular biosynthetic process 4.66E-07 50 35 7.96E-06 29 24 8 33.33333333 18 GO:0051254 positive regulation of RNA metabolic process 4.49E-07 47 33 3.06E-05 26 21 7 33.33333333 18 GO:1903508 positive regulation of nucleic acid-templated transcription 4.15E-08 46 32 3.57E-05 25 21 7 33.33333333 18 GO:0045893 "positive regulation of transcription, DNA-templated" 4.15E-08 46 32 3.57E-05 25 21 7 33.33333333 18 GO:1902680 positive regulation of RNA biosynthetic process 4.20E-07 46 32 4.95E-05 25 21 7 33.33333333 21 GO:0035262 gonad morphogenesis 2.22E-05 5 4 1.87E-04 7 6 2 33.33333333 31 GO:0040034 "regulation of development, heterochronic" 1.60E-04 5 4 2.41E-05 10 6 2 33.33333333 31 GO:0001704 formation of primary germ layer 1.57E-04 11 8 1.70E-04 15 9 3 33.33333333 31 GO:0001707 mesoderm formation 1.85E-03 6 4 1.02E-03 8 6 2 33.33333333 31 GO:0048332 mesoderm morphogenesis 5.19E-04 7 5 1.45E-03 8 6 2 33.33333333 37 GO:0090598 male anatomical structure morphogenesis 1.37E-04 13 9 3.53E-09 41 24 8 33.33333333 37 GO:0051046 regulation of secretion 3.48E-04 15 13 5.96E-05 21 18 6 33.33333333 37 GO:0007498 mesoderm development 4.46E-05 11 8 4.81E-04 18 15 5 33.33333333 37 GO:0016079 synaptic vesicle exocytosis 2.71E-05 8 6 1.56E-03 10 6 2 33.33333333 37 GO:0007517 muscle organ development 2.99E-08 21 13 1.75E-03 22 15 5 33.33333333 41 GO:0045165 cell fate commitment 9.49E-07 33 24 3.82E-08 50 36 12 33.33333333 41 GO:0045595 regulation of cell differentiation 7.06E-08 39 27 1.53E-06 38 33 11 33.33333333 41 GO:0000122 negative regulation of transcription from RNA polymerase II promoter 1.43E-06 22 16 3.25E-05 24 15 5 33.33333333 18 GO:0080090 regulation of primary metabolic process 2.73E-09 138 99 4.90E-06 128 91 30 32.96703297 18 GO:0031323 regulation of cellular metabolic process 2.76E-09 142 102 2.03E-05 129 91 30 32.96703297 18 GO:0034645 cellular macromolecule biosynthetic process 8.08E-05 145 104 1.53E-03 133 91 30 32.96703297 37 GO:0040012 regulation of locomotion 8.73E-07 48 38 6.19E-18 93 70 23 32.85714286 5 GO:0009605 response to external stimulus 5.82E-13 100 68 4.09E-09 74 61 20 32.78688525 5 GO:0010604 positive regulation of macromolecule metabolic process 4.64E-04 83 51 5.60E-12 59 46 15 32.60869565 5 GO:0050789 regulation of biological process 1.08E-14 650 439 1.22E-40 558 396 129 32.57575758 5 GO:0000902 cell morphogenesis 1.01E-10 84 59 3.95E-07 49 43 14 32.55813953 5 GO:0006935 chemotaxis 2.11E-10 55 40 1.62E-08 42 37 12 32.43243243 5 GO:0042330 taxis 1.17E-10 60 43 1.10E-07 42 37 12 32.43243243 5 GO:0061564 axon development 1.54E-12 60 45 2.22E-07 48 37 12 32.43243243 5 GO:0048667 cell morphogenesis involved in neuron differentiation 2.99E-11 60 43 6.06E-08 38 34 11 32.35294118 5 GO:0050794 regulation of cellular process 5.77E-23 477 326 1.29E-38 472 334 108 32.33532934 5 GO:0018991 oviposition 3.37E-07 75 52 3.52E-13 92 65 21 32.30769231 14 GO:0016477 cell migration 6.07E-07 35 26 5.34E-07 40 31 10 32.25806452 14 GO:0051674 localization of cell 4.88E-07 36 27 9.86E-07 40 31 10 32.25806452 14 GO:0048870 cell motility 4.48E-07 36 27 9.86E-07 40 31 10 32.25806452 18 GO:0009059 macromolecule biosynthetic process 5.65E-05 147 105 1.20E-03 135 93 30 32.25806452 5 GO:0048731 system development 2.34E-12 316 203 1.16E-15 252 180 58 32.22222222 37 GO:0008134 transcription factor binding 5.67E-06 28 21 4.88E-07 42 28 9 32.14285714 5 GO:0009968 negative regulation of signal transduction 1.43E-04 34 24 3.31E-08 31 25 8 32 5 GO:0005216 ion channel activity 3.70E-05 59 42 3.01E-03 42 25 8 32 37 GO:0023061 signal release 1.61E-07 22 17 4.73E-08 31 25 8 32 5 GO:0046872 metal ion binding 9.45E-09 180 134 1.97E-11 268 172 55 31.97674419 18 GO:0060255 regulation of macromolecule metabolic process 1.29E-09 147 105 1.43E-05 139 97 31 31.95876289 5 GO:0048523 negative regulation of cellular process 1.69E-06 139 87 8.46E-15 109 72 23 31.94444444 5 GO:0032501 multicellular organismal process 1.24E-07 666 438 1.96E-07 620 418 133 31.81818182 14 GO:0007411 axon guidance 1.61E-07 20 15 3.84E-09 24 22 7 31.81818182 14 GO:0097485 neuron projection guidance 1.90E-07 20 15 4.51E-09 24 22 7 31.81818182 5 GO:0043169 cation binding 2.20E-08 182 136 1.21E-11 270 173 55 31.79190751 5 GO:0065007 biological regulation 4.91E-15 672 453 3.65E-29 608 416 132 31.73076923 5 GO:0097159 organic cyclic compound binding 1.45E-04 355 228 1.44E-11 399 268 85 31.71641791 5 GO:1901363 heterocyclic compound binding 2.38E-04 352 226 5.00E-11 395 265 84 31.69811321 5 GO:0007275 multicellular organismal development 4.84E-06 593 389 1.00E-05 553 366 116 31.69398907 5 GO:0000904 cell morphogenesis involved in differentiation 9.38E-12 69 47 1.75E-09 43 38 12 31.57894737 31 GO:0030054 cell junction 7.61E-09 39 28 8.25E-11 57 38 12 31.57894737 37 GO:0044456 synapse part 1.20E-06 32 23 2.93E-06 44 35 11 31.42857143 5 GO:0022603 regulation of anatomical structure morphogenesis 3.52E-06 40 27 1.15E-04 20 16 5 31.25 5 GO:0051049 regulation of transport 5.46E-04 43 25 2.07E-04 28 16 5 31.25 31 GO:0005096 GTPase activator activity 1.54E-03 8 7 4.10E-05 20 16 5 31.25 41 GO:0034330 cell junction organization 8.26E-04 11 11 6.42E-11 18 16 5 31.25 5 GO:0044707 single-multicellular organism process 8.63E-08 637 418 2.03E-06 594 398 124 31.15577889 14 GO:0018991 oviposition 2.25E-07 36 26 7.87E-11 55 45 14 31.11111111 5 GO:0032502 developmental process 3.50E-07 646 423 3.11E-06 601 399 124 31.07769424 18 GO:0040012 regulation of locomotion 9.76E-15 65 45 7.12E-09 36 29 9 31.03448276 37 GO:0046661 male sex differentiation 2.89E-06 18 12 7.51E-10 47 29 9 31.03448276 5 GO:0048856 anatomical structure development 2.16E-07 574 376 3.26E-08 524 350 108 30.85714286 5 GO:0022838 substrate-specific channel activity 1.02E-04 59 42 1.53E-03 44 26 8 30.76923077 14 GO:0048858 cell projection morphogenesis 8.77E-06 26 19 3.59E-08 30 26 8 30.76923077 14 GO:0032990 cell part morphogenesis 1.36E-05 26 19 6.81E-08 30 26 8 30.76923077 14 GO:0050767 regulation of neurogenesis 1.72E-05 15 13 3.09E-07 14 13 4 30.76923077 37 GO:0022843 voltage-gated cation channel activity 8.63E-05 11 7 8.72E-08 25 13 4 30.76923077 37 GO:0034703 cation channel complex 3.82E-04 9 6 3.96E-07 21 13 4 30.76923077 41 GO:0007389 pattern specification process 1.18E-08 36 28 1.21E-06 36 26 8 30.76923077 5 GO:0048513 organ development 8.38E-08 248 153 7.57E-11 198 140 43 30.71428571 5 GO:0016043 cellular component organization 3.04E-05 275 177 3.89E-08 245 163 50 30.67484663 5 GO:0044767 single-organism developmental process 2.51E-06 626 408 2.50E-06 599 397 121 30.47858942 5 GO:0016477 cell migration 2.30E-11 86 55 1.95E-08 68 46 14 30.43478261 5 GO:0051674 localization of cell 2.67E-11 88 56 5.15E-08 68 46 14 30.43478261 5 GO:0048870 cell motility 5.55E-11 87 56 5.15E-08 68 46 14 30.43478261 18 GO:0045935 positive regulation of nucleobase-containing compound metabolic process 2.00E-07 50 34 1.29E-05 28 23 7 30.43478261 31 GO:0007389 pattern specification process 7.48E-07 31 24 1.97E-07 37 23 7 30.43478261 37 GO:0007268 synaptic transmission 1.41E-06 32 22 4.54E-10 62 46 14 30.43478261 37 GO:0050804 regulation of synaptic transmission 3.55E-04 12 8 1.42E-08 28 23 7 30.43478261 5 GO:0032989 cellular component morphogenesis 1.00E-12 102 68 3.71E-06 78 56 17 30.35714286 31 GO:0043565 sequence-specific DNA binding 7.43E-17 57 45 1.00E-07 103 66 20 30.3030303 5 GO:0009987 cellular process 1.98E-05 831 538 1.25E-24 828 560 169 30.17857143 5 GO:0010646 regulation of cell communication 3.04E-06 96 63 7.59E-12 82 63 19 30.15873016 5 GO:0023051 regulation of signaling 5.49E-06 95 63 1.52E-11 81 63 19 30.15873016 5 GO:0033057 multicellular organismal reproductive behavior 7.53E-07 81 56 1.33E-15 103 73 22 30.1369863 5 GO:0071840 cellular component organization or biogenesis 2.09E-04 280 181 7.92E-08 251 166 50 30.12048193 18 GO:0001709 cell fate determination 5.21E-05 13 8 6.47E-06 13 10 3 30 18 GO:0043025 neuronal cell body 1.68E-03 21 17 3.19E-05 25 20 6 30 31 GO:0007498 mesoderm development 2.89E-05 10 8 1.41E-04 13 10 3 30 41 GO:0001667 ameboidal-type cell migration 6.90E-04 14 11 2.54E-04 13 10 3 30 41 GO:0031253 cell projection membrane 1.33E-03 9 6 4.35E-04 13 10 3 30 5 GO:0044699 single-organism process 3.41E-11 922 608 5.37E-14 915 608 182 29.93421053 5 GO:0044706 multi-multicellular organism process 4.65E-08 88 61 8.44E-16 104 74 22 29.72972973 5 GO:0051239 regulation of multicellular organismal process 3.31E-07 165 111 7.31E-16 167 128 38 29.6875 5 GO:0048583 regulation of response to stimulus 1.04E-07 118 82 1.69E-15 104 81 24 29.62962963 5 GO:0030001 metal ion transport 1.54E-03 41 24 5.26E-05 42 27 8 29.62962963 14 GO:0000904 cell morphogenesis involved in differentiation 2.81E-05 25 18 2.45E-11 32 27 8 29.62962963 18 GO:0010604 positive regulation of macromolecule metabolic process 1.56E-06 64 42 1.18E-05 36 27 8 29.62962963 37 GO:0007389 pattern specification process 1.18E-08 40 29 4.35E-10 63 44 13 29.54545455 41 GO:0003677 DNA binding 2.99E-10 82 63 3.61E-05 157 95 28 29.47368421 5 GO:0035556 intracellular signal transduction 1.27E-03 89 56 1.10E-10 93 68 20 29.41176471 5 GO:0002009 morphogenesis of an epithelium 2.33E-06 97 62 1.02E-04 22 17 5 29.41176471 18 GO:0007155 cell adhesion 6.55E-09 32 22 3.74E-05 20 17 5 29.41176471 18 GO:0022610 biological adhesion 6.55E-09 32 22 5.57E-05 20 17 5 29.41176471 5 GO:0042221 response to chemical 8.08E-10 157 104 2.92E-05 121 92 27 29.34782609 41 GO:0043565 sequence-specific DNA binding 3.80E-14 55 46 1.75E-08 108 65 19 29.23076923 5 GO:0008092 cytoskeletal protein binding 4.48E-04 39 26 1.36E-06 34 24 7 29.16666667 14 GO:0033057 multicellular organismal reproductive behavior 5.51E-07 38 28 2.37E-11 59 48 14 29.16666667 14 GO:0019098 reproductive behavior 1.22E-07 40 30 3.02E-11 59 48 14 29.16666667 14 GO:0044705 multi-organism reproductive behavior 1.03E-07 40 30 3.02E-11 59 48 14 29.16666667 14 GO:0051705 multi-organism behavior 7.61E-08 41 30 3.85E-11 59 48 14 29.16666667 14 GO:0006935 chemotaxis 9.30E-06 22 16 3.02E-07 26 24 7 29.16666667 14 GO:0042330 taxis 5.75E-05 22 16 1.05E-06 26 24 7 29.16666667 18 GO:0051173 positive regulation of nitrogen compound metabolic process 2.39E-07 51 34 2.44E-06 30 24 7 29.16666667 37 GO:0000122 negative regulation of transcription from RNA polymerase II promoter 8.11E-09 28 18 2.28E-06 39 24 7 29.16666667 37 GO:0060341 regulation of cellular localization 7.97E-05 22 15 7.94E-04 29 24 7 29.16666667 5 GO:0006366 transcription from RNA polymerase II promoter 3.43E-04 77 48 9.08E-15 74 55 16 29.09090909 5 GO:0050793 regulation of developmental process 6.74E-08 162 110 6.89E-15 153 117 34 29.05982906 5 GO:0030029 actin filament-based process 1.11E-07 53 35 1.98E-04 49 31 9 29.03225806 14 GO:0030030 cell projection organization 3.24E-06 34 25 2.22E-07 39 31 9 29.03225806 37 GO:0045202 synapse 1.67E-09 47 33 1.00E-08 77 62 18 29.03225806 5 GO:0043167 ion binding 1.94E-07 299 200 2.76E-12 400 262 76 29.00763359 4 GO:0048582 positive regulation of post-embryonic development 1.79E-04 6 6 3.90E-04 14 14 4 28.57142857 4 GO:0061063 positive regulation of nematode larval development 1.79E-04 6 6 3.90E-04 14 14 4 28.57142857 4 GO:0034329 cell junction assembly 4.10E-05 8 8 5.16E-04 8 7 2 28.57142857 4 GO:0035262 gonad morphogenesis 5.18E-04 5 4 1.15E-03 8 7 2 28.57142857 5 GO:0070588 calcium ion transmembrane transport 3.63E-04 12 8 1.50E-04 10 7 2 28.57142857 5 GO:0010721 negative regulation of cell development 2.69E-04 13 7 6.49E-04 8 7 2 28.57142857 14 GO:0044706 multi-multicellular organism process 6.98E-07 39 29 1.09E-11 60 49 14 28.57142857 14 GO:0040012 regulation of locomotion 2.15E-07 34 28 4.20E-10 31 28 8 28.57142857 14 GO:0051960 regulation of nervous system development 4.16E-05 16 13 6.28E-08 16 14 4 28.57142857 18 GO:0031325 positive regulation of cellular metabolic process 8.63E-06 64 42 1.55E-04 37 28 8 28.57142857 18 GO:0000976 transcription regulatory region sequence-specific DNA binding 6.14E-07 17 13 1.13E-03 12 7 2 28.57142857 18 GO:0007269 neurotransmitter secretion 7.26E-05 14 11 1.53E-03 10 7 2 28.57142857 31 GO:0001708 cell fate specification 5.83E-08 23 18 7.27E-09 40 28 8 28.57142857 31 GO:0030055 cell-substrate junction 2.68E-04 8 5 1.50E-06 11 7 2 28.57142857 31 GO:0060795 cell fate commitment involved in formation of primary germ layer 4.70E-04 8 5 1.04E-04 13 7 2 28.57142857 37 GO:0007267 cell-cell signaling 4.29E-07 44 32 8.46E-14 85 63 18 28.57142857 37 GO:0051962 positive regulation of nervous system development 3.54E-04 11 7 1.11E-09 15 14 4 28.57142857 37 GO:0005244 voltage-gated ion channel activity 1.32E-04 12 7 6.10E-08 29 14 4 28.57142857 37 GO:0022832 voltage-gated channel activity 1.32E-04 12 7 6.10E-08 29 14 4 28.57142857 37 GO:0010720 positive regulation of cell development 7.33E-04 10 6 1.43E-07 14 14 4 28.57142857 37 GO:0031672 A band 1.93E-03 9 7 2.68E-07 20 14 4 28.57142857 37 GO:0031430 M band 1.10E-03 8 6 5.21E-07 18 14 4 28.57142857 37 GO:0031012 extracellular matrix 3.16E-05 20 11 6.12E-05 33 21 6 28.57142857 41 GO:0009887 organ morphogenesis 9.44E-08 45 30 4.47E-05 32 28 8 28.57142857 41 GO:0048663 neuron fate commitment 7.83E-04 8 4 8.47E-04 8 7 2 28.57142857 41 GO:0030900 forebrain development 6.86E-04 11 7 3.13E-03 7 7 2 28.57142857 5 GO:0048519 negative regulation of biological process 1.13E-05 180 113 1.21E-13 155 109 31 28.44036697 5 GO:0040011 locomotion 3.83E-19 332 213 6.68E-14 281 197 56 28.42639594 37 GO:0032879 regulation of localization 2.46E-06 50 36 3.85E-12 107 74 21 28.37837838 5 GO:0030154 cell differentiation 1.52E-10 205 133 7.83E-16 206 141 40 28.36879433 37 GO:0001071 nucleic acid binding transcription factor activity 1.79E-20 67 51 2.01E-10 197 124 35 28.22580645 37 GO:0043565 sequence-specific DNA binding 1.16E-13 60 47 3.63E-10 185 117 33 28.20512821 41 GO:0040012 regulation of locomotion 1.55E-06 42 35 5.02E-08 47 39 11 28.20512821 18 GO:0048598 embryonic morphogenesis 8.07E-07 53 33 1.33E-09 39 25 7 28 41 GO:0060429 epithelium development 1.59E-05 65 44 6.48E-05 34 25 7 28 5 GO:0048869 cellular developmental process 2.00E-10 216 141 1.19E-14 209 143 40 27.97202797 5 GO:0050896 response to stimulus 4.57E-13 381 258 1.10E-22 376 279 78 27.95698925 14 GO:0030182 neuron differentiation 1.15E-09 43 33 9.29E-14 52 43 12 27.90697674 5 GO:0009966 regulation of signal transduction 1.78E-04 77 51 6.32E-10 70 54 15 27.77777778 18 GO:0006366 transcription from RNA polymerase II promoter 2.07E-07 62 42 2.23E-08 49 36 10 27.77777778 18 GO:0009887 organ morphogenesis 1.72E-11 59 42 1.60E-05 24 18 5 27.77777778 31 GO:0045138 nematode male tail tip morphogenesis 5.84E-04 10 8 2.14E-10 30 18 5 27.77777778 5 GO:0023052 signaling 7.08E-19 281 198 4.45E-25 297 220 61 27.72727273 31 GO:0001071 nucleic acid binding transcription factor activity 3.88E-19 57 42 1.78E-06 104 65 18 27.69230769 31 GO:0003700 sequence-specific DNA binding transcription factor activity 3.06E-19 57 42 1.78E-06 104 65 18 27.69230769 5 GO:0005886 plasma membrane 2.52E-11 153 88 6.39E-15 130 91 25 27.47252747 18 GO:0019222 regulation of metabolic process 1.63E-09 164 118 3.74E-08 171 124 34 27.41935484 37 GO:0003700 sequence-specific DNA binding transcription factor activity 6.56E-20 66 50 2.01E-10 197 124 34 27.41935484 5 GO:0007154 cell communication 1.37E-19 287 200 4.97E-26 303 223 61 27.35426009 37 GO:0006355 "regulation of transcription, DNA-templated" 2.63E-12 104 72 4.17E-11 288 183 50 27.32240437 37 GO:1903506 regulation of nucleic acid-templated transcription 2.63E-12 104 72 4.17E-11 288 183 50 27.32240437 5 GO:0044700 single organism signaling 1.78E-18 276 194 4.06E-25 297 220 60 27.27272727 5 GO:0071944 cell periphery 5.17E-13 170 98 7.28E-16 144 99 27 27.27272727 5 GO:0005261 cation channel activity 1.32E-04 32 23 2.54E-05 33 22 6 27.27272727 5 GO:0050804 regulation of synaptic transmission 1.08E-04 17 11 4.79E-05 14 11 3 27.27272727 14 GO:0048699 generation of neurons 1.62E-10 47 36 4.35E-13 53 44 12 27.27272727 14 GO:0022008 neurogenesis 2.47E-08 47 36 3.33E-12 53 44 12 27.27272727 14 GO:0048666 neuron development 6.37E-10 38 28 1.43E-09 41 33 9 27.27272727 14 GO:0006928 movement of cell or subcellular component 2.67E-06 43 31 9.28E-09 55 44 12 27.27272727 31 GO:0046661 male sex differentiation 1.04E-05 15 10 6.46E-11 34 22 6 27.27272727 41 GO:0003676 nucleic acid binding 1.27E-10 130 100 3.73E-05 255 158 43 27.21518987 37 GO:0019438 aromatic compound biosynthetic process 2.62E-09 132 89 2.05E-09 344 217 59 27.18894009 37 GO:2001141 regulation of RNA biosynthetic process 1.78E-11 104 72 2.86E-11 290 184 50 27.17391304 37 GO:0051252 regulation of RNA metabolic process 7.48E-11 107 74 8.05E-12 296 189 51 26.98412698 37 GO:0006351 "transcription, DNA-templated" 4.34E-09 111 75 1.14E-10 299 189 51 26.98412698 37 GO:0097659 nucleic acid-templated transcription 4.34E-09 111 75 2.33E-10 299 189 51 26.98412698 5 GO:0005509 calcium ion binding 2.51E-04 30 22 1.22E-04 36 26 7 26.92307692 5 GO:0030036 actin cytoskeleton organization 5.32E-06 46 31 2.86E-03 43 26 7 26.92307692 5 GO:0044763 single-organism cellular process 7.52E-11 624 416 1.09E-24 685 469 126 26.86567164 37 GO:0032774 RNA biosynthetic process 1.53E-08 111 75 2.31E-10 302 190 51 26.84210526 37 GO:1901362 organic cyclic compound biosynthetic process 1.63E-08 133 90 2.01E-08 348 220 59 26.81818182 37 GO:0019219 regulation of nucleobase-containing compound metabolic process 1.76E-10 112 78 6.18E-11 302 194 52 26.80412371 37 GO:0009887 organ morphogenesis 8.42E-09 53 35 1.72E-12 67 56 15 26.78571429 37 GO:0034654 nucleobase-containing compound biosynthetic process 1.22E-09 130 87 9.57E-10 338 213 57 26.76056338 4 GO:0046661 male sex differentiation 2.20E-04 9 8 4.89E-09 26 15 4 26.66666667 5 GO:0048585 negative regulation of response to stimulus 8.41E-06 44 28 4.86E-09 37 30 8 26.66666667 5 GO:0000122 negative regulation of transcription from RNA polymerase II promoter 3.99E-06 32 19 1.02E-06 24 15 4 26.66666667 31 GO:0003002 regionalization 2.02E-06 24 17 3.96E-06 25 15 4 26.66666667 37 GO:0051171 regulation of nitrogen compound metabolic process 1.09E-10 115 80 5.46E-11 304 195 52 26.66666667 37 GO:0007638 mechanosensory behavior 1.18E-03 9 6 1.14E-05 19 15 4 26.66666667 41 GO:0008134 transcription factor binding 6.61E-06 25 17 1.51E-03 21 15 4 26.66666667 14 GO:0007399 nervous system development 2.10E-07 54 41 6.30E-14 61 49 13 26.53061224 5 GO:0022414 reproductive process 6.08E-05 238 154 1.85E-13 268 181 48 26.51933702 37 GO:0018130 heterocycle biosynthetic process 7.65E-09 131 88 2.42E-09 347 219 58 26.48401826 5 GO:0006357 regulation of transcription from RNA polymerase II promoter 4.47E-06 72 46 1.27E-16 72 53 14 26.41509434 37 GO:0003677 DNA binding 1.14E-10 94 69 3.26E-07 289 178 47 26.40449438 5 GO:0051094 positive regulation of developmental process 7.85E-05 84 54 4.33E-10 94 72 19 26.38888889 5 GO:0060089 molecular transducer activity 1.60E-13 111 82 1.79E-06 126 95 25 26.31578947 5 GO:0032403 protein complex binding 8.20E-04 29 18 3.08E-05 25 19 5 26.31578947 5 GO:0005887 integral component of plasma membrane 2.19E-04 31 21 6.40E-05 26 19 5 26.31578947 31 GO:0090598 male anatomical structure morphogenesis 2.41E-04 11 8 5.83E-11 31 19 5 26.31578947 37 GO:0051049 regulation of transport 8.39E-04 29 19 8.35E-08 61 38 10 26.31578947 41 GO:0019098 reproductive behavior 1.12E-05 47 33 1.10E-10 105 76 20 26.31578947 41 GO:0051253 negative regulation of RNA metabolic process 4.82E-07 30 21 3.43E-06 31 19 5 26.31578947 41 GO:1902679 negative regulation of RNA biosynthetic process 1.88E-07 30 21 4.73E-06 30 19 5 26.31578947 41 GO:1903507 negative regulation of nucleic acid-templated transcription 1.60E-07 30 21 4.73E-06 30 19 5 26.31578947 41 GO:0045892 "negative regulation of transcription, DNA-templated" 1.60E-07 30 21 4.73E-06 30 19 5 26.31578947 5 GO:0007165 signal transduction 2.26E-14 235 165 1.90E-23 279 206 54 26.21359223 31 GO:0006351 "transcription, DNA-templated" 7.91E-11 97 67 3.83E-07 159 103 27 26.21359223 31 GO:0097659 nucleic acid-templated transcription 7.91E-11 97 67 5.57E-07 159 103 27 26.21359223 31 GO:0003677 DNA binding 1.00E-10 79 57 1.09E-05 156 103 27 26.21359223 37 GO:0044708 single-organism behavior 4.09E-06 28 19 1.81E-07 52 42 11 26.19047619 5 GO:0046873 metal ion transmembrane transporter activity 1.75E-03 37 25 7.51E-04 36 23 6 26.08695652 18 GO:0044297 cell body 7.51E-04 24 18 1.45E-05 28 23 6 26.08695652 18 GO:0045202 synapse 4.45E-07 42 31 5.06E-05 29 23 6 26.08695652 37 GO:0022604 regulation of cell morphogenesis 6.04E-04 17 11 1.12E-05 26 23 6 26.08695652 41 GO:0043050 pharyngeal pumping 4.61E-05 16 12 3.06E-09 29 23 6 26.08695652 41 GO:0042755 eating behavior 7.92E-05 16 12 5.91E-09 29 23 6 26.08695652 5 GO:0051240 positive regulation of multicellular organismal process 1.39E-04 84 55 4.22E-09 97 73 19 26.02739726 37 GO:2000112 regulation of cellular macromolecule biosynthetic process 2.10E-11 111 75 2.27E-10 307 196 51 26.02040816 37 GO:0044271 cellular nitrogen compound biosynthetic process 2.84E-09 134 89 3.15E-10 354 223 58 26.00896861 31 GO:0006355 "regulation of transcription, DNA-templated" 7.66E-14 91 63 5.60E-08 156 100 26 26 31 GO:1903506 regulation of nucleic acid-templated transcription 7.66E-14 91 63 5.60E-08 156 100 26 26 37 GO:0031326 regulation of cellular biosynthetic process 2.27E-11 115 77 6.09E-11 313 200 52 26 37 GO:0009889 regulation of biosynthetic process 3.31E-11 115 77 7.71E-11 314 200 52 26 31 GO:0032774 RNA biosynthetic process 1.21E-10 98 67 2.74E-07 162 104 27 25.96153846 18 GO:0045595 regulation of cell differentiation 1.98E-08 45 31 7.11E-09 32 27 7 25.92592593 31 GO:0003676 nucleic acid binding 4.57E-10 121 90 1.73E-03 235 162 42 25.92592593 37 GO:0010556 regulation of macromolecule biosynthetic process 7.74E-11 112 76 1.41E-10 310 197 51 25.88832487 37 GO:1902679 negative regulation of RNA biosynthetic process 1.88E-09 37 24 4.59E-07 48 31 8 25.80645161 37 GO:1903507 negative regulation of nucleic acid-templated transcription 1.52E-09 37 24 4.59E-07 48 31 8 25.80645161 37 GO:0045892 "negative regulation of transcription, DNA-templated" 1.52E-09 37 24 4.59E-07 48 31 8 25.80645161 37 GO:0051253 negative regulation of RNA metabolic process 6.39E-09 37 24 5.78E-07 49 31 8 25.80645161 31 GO:2001141 regulation of RNA biosynthetic process 4.75E-13 91 63 2.72E-08 158 101 26 25.74257426 18 GO:0006357 regulation of transcription from RNA polymerase II promoter 8.05E-09 57 41 3.65E-09 47 35 9 25.71428571 31 GO:0051252 regulation of RNA metabolic process 1.15E-12 94 65 8.36E-09 162 105 27 25.71428571 18 GO:1901363 heterocyclic compound binding 2.01E-04 223 161 1.88E-06 280 184 47 25.54347826 18 GO:0097159 organic cyclic compound binding 2.49E-04 223 161 2.59E-06 280 184 47 25.54347826 37 GO:0048729 tissue morphogenesis 2.64E-06 69 44 2.47E-09 56 47 12 25.53191489 5 GO:0065009 regulation of molecular function 2.22E-03 72 48 7.17E-10 76 55 14 25.45454545 5 GO:0007548 sex differentiation 2.43E-04 138 86 2.19E-07 149 95 24 25.26315789 31 GO:0019219 regulation of nucleobase-containing compound metabolic process 4.12E-11 95 65 4.83E-08 164 107 27 25.23364486 31 GO:2000112 regulation of cellular macromolecule biosynthetic process 1.72E-13 98 67 4.92E-08 168 107 27 25.23364486 31 GO:0034654 nucleobase-containing compound biosynthetic process 3.58E-11 112 74 1.54E-05 173 111 28 25.22522523 5 GO:0044703 multi-organism reproductive process 1.55E-04 140 88 3.83E-11 173 119 30 25.21008403 5 GO:0051716 cellular response to stimulus 5.95E-09 260 180 1.93E-19 295 219 55 25.11415525 3 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity 1.30E-07 13 9 5.43E-09 26 16 4 25 4 GO:0045138 nematode male tail tip morphogenesis 6.66E-04 7 6 1.29E-08 23 12 3 25 4 GO:0001709 cell fate determination 5.75E-04 7 6 2.70E-05 13 8 2 25 4 GO:0031253 cell projection membrane 2.55E-04 7 4 2.36E-04 11 8 2 25 5 GO:0048468 cell development 4.27E-11 157 100 1.79E-08 151 108 27 25 5 GO:2000113 negative regulation of cellular macromolecule biosynthetic process 3.52E-06 49 30 3.03E-08 36 24 6 25 5 GO:0010558 negative regulation of macromolecule biosynthetic process 2.13E-06 50 31 3.03E-08 36 24 6 25 5 GO:1902679 negative regulation of RNA biosynthetic process 4.33E-07 45 27 6.49E-08 30 20 5 25 5 GO:1903507 negative regulation of nucleic acid-templated transcription 3.46E-07 45 27 6.49E-08 30 20 5 25 5 GO:0045892 "negative regulation of transcription, DNA-templated" 3.46E-07 45 27 6.49E-08 30 20 5 25 5 GO:0051253 negative regulation of RNA metabolic process 1.56E-06 45 27 1.49E-07 30 20 5 25 5 GO:0003779 actin binding 1.03E-03 21 12 3.04E-05 21 12 3 25 5 GO:0006816 calcium ion transport 6.88E-04 16 9 3.26E-04 12 8 2 25 5 GO:0070838 divalent metal ion transport 2.11E-03 17 10 6.39E-04 12 8 2 25 11 GO:0070161 anchoring junction 3.92E-05 9 7 1.24E-11 25 16 4 25 11 GO:0005912 adherens junction 3.33E-05 9 7 1.79E-10 23 16 4 25 11 GO:0007517 muscle organ development 1.67E-04 9 7 1.24E-03 21 16 4 25 11 GO:0045026 plasma membrane fusion 6.76E-04 3 2 2.62E-03 6 4 1 25 14 GO:0007548 sex differentiation 1.36E-04 57 37 1.93E-05 80 56 14 25 18 GO:0050767 regulation of neurogenesis 4.16E-06 22 16 1.83E-07 17 16 4 25 18 GO:1902531 regulation of intracellular signal transduction 6.40E-06 38 28 2.04E-05 34 28 7 25 18 GO:0007268 synaptic transmission 1.29E-03 25 17 8.71E-04 20 16 4 25 18 GO:0040017 positive regulation of locomotion 1.44E-06 34 18 1.80E-03 10 8 2 25 21 GO:0031672 A band 2.81E-04 5 4 1.88E-03 6 4 1 25 31 GO:0018991 oviposition 2.48E-06 42 29 3.20E-11 98 68 17 25 31 GO:0010556 regulation of macromolecule biosynthetic process 3.05E-14 102 69 2.99E-08 170 108 27 25 31 GO:0000976 transcription regulatory region sequence-specific DNA binding 1.74E-09 18 12 1.26E-07 23 16 4 25 31 GO:0044271 cellular nitrogen compound biosynthetic process 4.56E-11 116 77 1.43E-05 180 116 29 25 31 GO:0035262 gonad morphogenesis 2.67E-04 7 5 1.23E-04 11 8 2 25 31 GO:0009952 anterior/posterior pattern specification 8.18E-04 13 9 2.18E-04 17 12 3 25 31 GO:0001709 cell fate determination 6.24E-08 15 9 8.60E-04 13 8 2 25 37 GO:0035239 tube morphogenesis 3.01E-06 29 20 1.36E-07 31 24 6 25 37 GO:0034765 regulation of ion transmembrane transport 3.96E-04 7 4 7.54E-06 20 12 3 25 37 GO:0034762 regulation of transmembrane transport 3.96E-04 7 4 7.54E-06 20 12 3 25 37 GO:0050770 regulation of axonogenesis 1.93E-03 9 7 1.40E-05 17 16 4 25 37 GO:0009952 anterior/posterior pattern specification 9.08E-05 17 12 2.37E-05 28 20 5 25 37 GO:0031594 neuromuscular junction 8.76E-04 7 3 6.60E-04 12 8 2 25 41 GO:0044705 multi-organism reproductive behavior 2.08E-05 46 32 1.10E-10 105 76 19 25 41 GO:0051705 multi-organism behavior 9.01E-06 48 32 1.58E-10 105 76 19 25 41 GO:0018991 oviposition 3.72E-05 41 28 1.84E-09 95 68 17 25 41 GO:0001071 nucleic acid binding transcription factor activity 2.32E-20 61 48 9.40E-09 115 68 17 25 41 GO:0003700 sequence-specific DNA binding transcription factor activity 9.33E-20 60 47 9.40E-09 115 68 17 25 41 GO:2000113 negative regulation of cellular macromolecule biosynthetic process 4.19E-07 33 23 1.80E-07 39 24 6 25 41 GO:0010558 negative regulation of macromolecule biosynthetic process 5.53E-07 33 23 1.80E-07 39 24 6 25 41 GO:0005912 adherens junction 9.88E-04 11 8 4.14E-07 15 12 3 25 41 GO:0070161 anchoring junction 1.18E-03 11 8 1.10E-06 15 12 3 25 41 GO:0044456 synapse part 6.96E-05 25 20 3.16E-05 27 24 6 25 41 GO:0043547 positive regulation of GTPase activity 8.63E-04 9 8 1.85E-04 21 16 4 25 41 GO:0009584 detection of visible light 1.73E-03 4 3 5.96E-04 7 4 1 25 41 GO:0009583 detection of light stimulus 1.73E-03 4 3 9.59E-04 7 4 1 25 41 GO:0035239 tube morphogenesis 6.44E-04 21 15 1.61E-03 15 12 3 25 41 GO:0048729 tissue morphogenesis 6.33E-05 56 39 2.24E-03 25 20 5 25 31 GO:0051171 regulation of nitrogen compound metabolic process 8.92E-11 96 65 1.60E-08 167 109 27 24.7706422 37 GO:0010468 regulation of gene expression 1.40E-09 120 80 3.78E-08 343 214 53 24.76635514 41 GO:0006351 "transcription, DNA-templated" 4.67E-08 94 70 1.50E-06 160 101 25 24.75247525 41 GO:0097659 nucleic acid-templated transcription 4.67E-08 94 70 2.15E-06 160 101 25 24.75247525 37 GO:0003676 nucleic acid binding 1.75E-08 141 108 5.40E-05 456 287 71 24.73867596 5 GO:0004872 receptor activity 1.22E-10 91 65 1.23E-03 100 73 18 24.65753425 31 GO:0019098 reproductive behavior 7.62E-06 45 32 3.51E-12 107 73 18 24.65753425 31 GO:0010468 regulation of gene expression 2.86E-12 107 72 2.16E-06 185 118 29 24.57627119 31 GO:0019438 aromatic compound biosynthetic process 1.21E-10 113 75 2.24E-05 176 114 28 24.56140351 31 GO:0031326 regulation of cellular biosynthetic process 9.63E-14 102 70 8.64E-09 173 110 27 24.54545455 31 GO:0009889 regulation of biosynthetic process 5.43E-14 103 70 1.31E-08 173 110 27 24.54545455 18 GO:0006928 movement of cell or subcellular component 8.97E-11 78 62 2.02E-09 73 53 13 24.52830189 37 GO:0048598 embryonic morphogenesis 3.36E-06 51 30 1.94E-09 80 53 13 24.52830189 41 GO:0016477 cell migration 1.13E-06 45 35 9.90E-07 73 53 13 24.52830189 41 GO:0051674 localization of cell 1.96E-07 48 37 2.48E-06 73 53 13 24.52830189 41 GO:0048870 cell motility 4.50E-07 47 37 2.48E-06 73 53 13 24.52830189 41 GO:0032774 RNA biosynthetic process 3.42E-08 96 70 1.77E-06 162 102 25 24.50980392 18 GO:0009893 positive regulation of metabolic process 1.17E-06 74 50 2.34E-08 57 45 11 24.44444444 5 GO:0007010 cytoskeleton organization 1.32E-04 75 46 2.88E-04 71 41 10 24.3902439 18 GO:0050793 regulation of developmental process 1.21E-07 108 74 3.47E-11 113 82 20 24.3902439 18 GO:0050789 regulation of biological process 7.40E-20 436 301 4.93E-18 374 267 65 24.34456929 5 GO:0048609 multicellular organismal reproductive process 4.46E-04 133 83 3.83E-10 163 111 27 24.32432432 5 GO:0032504 multicellular organism reproduction 4.79E-04 134 84 5.76E-10 163 111 27 24.32432432 31 GO:0044706 multi-multicellular organism process 6.91E-06 46 32 3.99E-12 107 74 18 24.32432432 37 GO:0022836 gated channel activity 1.31E-04 27 15 4.70E-05 65 37 9 24.32432432 18 GO:0030154 cell differentiation 1.00E-10 139 97 7.56E-10 145 107 26 24.29906542 18 GO:0007399 nervous system development 2.52E-11 94 69 1.95E-17 84 66 16 24.24242424 18 GO:0005515 protein binding 1.11E-05 230 158 4.30E-08 199 132 32 24.24242424 18 GO:0042221 response to chemical 4.24E-09 105 76 1.50E-04 91 62 15 24.19354839 31 GO:0018130 heterocycle biosynthetic process 1.84E-10 113 75 2.02E-05 178 116 28 24.13793103 37 GO:2000241 regulation of reproductive process 1.56E-03 14 10 5.76E-07 38 29 7 24.13793103 5 GO:0016020 membrane 4.22E-08 383 241 5.49E-04 362 253 61 24.11067194 37 GO:0061061 muscle structure development 6.97E-08 34 22 4.10E-04 92 54 13 24.07407407 5 GO:0007166 cell surface receptor signaling pathway 1.32E-08 118 85 1.44E-16 124 100 24 24 31 GO:0043087 regulation of GTPase activity 2.21E-03 11 10 6.76E-06 33 25 6 24 31 GO:0044093 positive regulation of molecular function 2.14E-03 25 16 1.84E-04 33 25 6 24 37 GO:0007369 gastrulation 5.53E-04 25 14 1.38E-06 34 25 6 24 41 GO:0033057 multicellular organismal reproductive behavior 1.32E-04 43 29 1.69E-10 104 75 18 24 41 GO:0007631 feeding behavior 1.85E-04 17 12 4.07E-09 33 25 6 24 41 GO:0006355 "regulation of transcription, DNA-templated" 1.01E-10 88 67 8.24E-08 159 100 24 24 41 GO:1903506 regulation of nucleic acid-templated transcription 1.01E-10 88 67 8.24E-08 159 100 24 24 31 GO:1901362 organic cyclic compound biosynthetic process 1.27E-09 113 75 4.61E-05 179 117 28 23.93162393 37 GO:0016070 RNA metabolic process 8.25E-04 124 85 1.20E-05 360 230 55 23.91304348 5 GO:0007186 G-protein coupled receptor signaling pathway 9.36E-07 44 39 5.52E-12 80 67 16 23.88059701 31 GO:0007610 behavior 2.14E-09 74 54 1.54E-18 153 109 26 23.85321101 37 GO:0031323 regulation of cellular metabolic process 1.62E-09 142 93 3.23E-09 376 239 57 23.84937238 5 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity 8.30E-07 27 17 8.76E-13 30 21 5 23.80952381 5 GO:0031226 intrinsic component of plasma membrane 1.59E-04 32 21 1.98E-05 28 21 5 23.80952381 37 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 3.79E-04 22 15 2.81E-04 29 21 5 23.80952381 37 GO:0042692 muscle cell differentiation 1.31E-05 23 15 3.86E-03 77 42 10 23.80952381 41 GO:0051252 regulation of RNA metabolic process 5.06E-10 92 70 7.67E-09 166 105 25 23.80952381 41 GO:0050767 regulation of neurogenesis 7.96E-07 21 13 1.36E-07 22 21 5 23.80952381 41 GO:0045934 negative regulation of nucleobase-containing compound metabolic process 4.48E-06 30 21 1.27E-05 33 21 5 23.80952381 41 GO:2001141 regulation of RNA biosynthetic process 5.00E-10 88 67 6.94E-08 160 101 24 23.76237624 18 GO:0005488 binding 3.46E-06 445 315 2.46E-10 495 320 76 23.75 37 GO:2000113 negative regulation of cellular macromolecule biosynthetic process 3.78E-08 39 25 5.81E-07 58 38 9 23.68421053 37 GO:0010558 negative regulation of macromolecule biosynthetic process 5.28E-08 39 25 5.81E-07 58 38 9 23.68421053 41 GO:0044706 multi-multicellular organism process 2.29E-05 47 32 1.24E-10 105 76 18 23.68421053 18 GO:0048869 cellular developmental process 5.92E-09 140 98 7.64E-10 150 110 26 23.63636364 31 GO:0033057 multicellular organismal reproductive behavior 4.84E-05 42 29 1.29E-11 105 72 17 23.61111111 18 GO:0050794 regulation of cellular process 1.82E-22 317 225 2.78E-16 310 225 53 23.55555556 5 GO:0031324 negative regulation of cellular metabolic process 9.06E-04 61 39 9.44E-08 55 34 8 23.52941176 5 GO:0006811 ion transport 8.33E-04 94 53 5.23E-04 84 51 12 23.52941176 14 GO:0009887 organ morphogenesis 5.91E-06 31 21 5.29E-06 20 17 4 23.52941176 18 GO:0030054 cell junction 1.74E-10 49 31 2.14E-11 44 34 8 23.52941176 18 GO:0016477 cell migration 8.34E-08 54 43 3.81E-07 52 34 8 23.52941176 18 GO:0051674 localization of cell 1.75E-08 57 45 8.02E-07 52 34 8 23.52941176 18 GO:0048870 cell motility 3.95E-08 56 45 8.02E-07 52 34 8 23.52941176 37 GO:0007411 axon guidance 1.77E-08 29 21 4.83E-09 57 51 12 23.52941176 37 GO:0097485 neuron projection guidance 2.23E-08 29 21 6.83E-09 57 51 12 23.52941176 37 GO:0045934 negative regulation of nucleobase-containing compound metabolic process 1.15E-07 37 24 2.77E-06 53 34 8 23.52941176 37 GO:0009612 response to mechanical stimulus 2.74E-04 13 8 1.03E-05 23 17 4 23.52941176 37 GO:0010769 regulation of cell morphogenesis involved in differentiation 1.37E-04 13 8 1.72E-05 18 17 4 23.52941176 18 GO:0048731 system development 2.98E-13 213 139 1.69E-11 185 132 31 23.48484848 41 GO:0034654 nucleobase-containing compound biosynthetic process 5.93E-08 108 77 8.16E-06 179 111 26 23.42342342 5 GO:0004871 signal transducer activity 6.74E-08 73 56 1.44E-06 122 94 22 23.40425532 41 GO:2000112 regulation of cellular macromolecule biosynthetic process 2.32E-10 95 70 8.40E-08 171 107 25 23.36448598 37 GO:0080090 regulation of primary metabolic process 5.77E-09 136 90 1.69E-11 376 244 57 23.36065574 4 GO:0045165 cell fate commitment 5.61E-08 23 18 2.26E-08 40 30 7 23.33333333 37 GO:0044212 transcription regulatory region DNA binding 3.18E-08 25 17 3.81E-10 44 30 7 23.33333333 37 GO:0000975 regulatory region DNA binding 1.18E-08 26 18 6.27E-10 44 30 7 23.33333333 37 GO:0001067 regulatory region nucleic acid binding 1.18E-08 26 18 6.27E-10 44 30 7 23.33333333 41 GO:0048518 positive regulation of biological process 1.03E-03 186 130 1.37E-15 215 150 35 23.33333333 41 GO:0050795 regulation of behavior 1.76E-05 21 18 1.08E-07 34 30 7 23.33333333 41 GO:0009891 positive regulation of biosynthetic process 1.01E-05 41 27 4.62E-06 41 30 7 23.33333333 41 GO:0031328 positive regulation of cellular biosynthetic process 8.35E-06 41 27 4.62E-06 41 30 7 23.33333333 41 GO:0010557 positive regulation of macromolecule biosynthetic process 1.53E-05 39 26 4.71E-06 40 30 7 23.33333333 31 GO:0044705 multi-organism reproductive behavior 1.47E-05 44 31 3.51E-12 107 73 17 23.28767123 31 GO:0051705 multi-organism behavior 2.91E-05 44 31 5.16E-12 107 73 17 23.28767123 18 GO:0032501 multicellular organismal process 2.39E-07 417 281 4.41E-08 472 310 72 23.22580645 37 GO:0045595 regulation of cell differentiation 9.69E-07 41 26 5.55E-11 69 56 13 23.21428571 18 GO:0046872 metal ion binding 2.62E-09 123 93 5.78E-06 184 125 29 23.2 41 GO:0019219 regulation of nucleobase-containing compound metabolic process 1.28E-09 96 72 2.80E-08 169 108 25 23.14814815 41 GO:0010556 regulation of macromolecule biosynthetic process 6.30E-10 96 71 5.25E-08 173 108 25 23.14814815 18 GO:0065007 biological regulation 5.55E-21 452 312 1.79E-11 408 281 65 23.1316726 4 GO:0090598 male anatomical structure morphogenesis 1.01E-03 7 6 3.21E-09 24 13 3 23.07692308 4 GO:0045595 regulation of cell differentiation 4.01E-05 20 16 4.93E-06 29 26 6 23.07692308 4 GO:0040026 positive regulation of vulval development 1.27E-03 5 5 8.22E-04 13 13 3 23.07692308 5 GO:0031327 negative regulation of cellular biosynthetic process 5.98E-06 49 30 3.75E-09 38 26 6 23.07692308 5 GO:0009890 negative regulation of biosynthetic process 3.66E-06 50 31 5.58E-09 38 26 6 23.07692308 14 GO:0022414 reproductive process 7.19E-07 101 72 2.85E-09 143 104 24 23.07692308 18 GO:0051239 regulation of multicellular organismal process 2.14E-09 118 80 1.88E-11 122 91 21 23.07692308 18 GO:0044459 plasma membrane part 1.52E-06 60 38 3.57E-10 55 39 9 23.07692308 18 GO:0042755 eating behavior 1.92E-03 15 12 6.19E-06 18 13 3 23.07692308 18 GO:2000113 negative regulation of cellular macromolecule biosynthetic process 5.81E-05 32 20 3.44E-04 22 13 3 23.07692308 18 GO:0010558 negative regulation of macromolecule biosynthetic process 7.32E-05 32 20 3.44E-04 22 13 3 23.07692308 18 GO:0031327 negative regulation of cellular biosynthetic process 8.21E-05 32 20 4.16E-04 22 13 3 23.07692308 18 GO:0009890 negative regulation of biosynthetic process 1.03E-04 32 20 5.01E-04 22 13 3 23.07692308 31 GO:0007155 cell adhesion 2.03E-08 27 18 1.88E-09 35 26 6 23.07692308 31 GO:0022610 biological adhesion 2.03E-08 27 18 4.19E-09 35 26 6 23.07692308 37 GO:0045165 cell fate commitment 2.30E-04 31 21 3.79E-17 97 65 15 23.07692308 37 GO:0031344 regulation of cell projection organization 2.28E-04 17 10 5.05E-08 28 26 6 23.07692308 37 GO:0090066 regulation of anatomical structure size 1.96E-03 16 10 3.36E-05 33 26 6 23.07692308 37 GO:0001764 neuron migration 4.53E-04 11 7 1.77E-03 14 13 3 23.07692308 41 GO:0060284 regulation of cell development 4.23E-07 24 16 3.75E-09 28 26 6 23.07692308 41 GO:0031327 negative regulation of cellular biosynthetic process 6.35E-07 33 23 2.88E-08 41 26 6 23.07692308 41 GO:0009890 negative regulation of biosynthetic process 8.31E-07 33 23 4.33E-08 41 26 6 23.07692308 41 GO:0010468 regulation of gene expression 3.18E-09 104 78 1.87E-06 190 117 27 23.07692308 18 GO:0043169 cation binding 1.17E-08 123 93 5.23E-06 185 126 29 23.01587302 31 GO:0016070 RNA metabolic process 1.13E-05 109 75 2.37E-04 190 126 29 23.01587302 41 GO:0019438 aromatic compound biosynthetic process 1.67E-07 109 78 1.85E-05 181 113 26 23.00884956 14 GO:0046872 metal ion binding 8.61E-09 78 61 1.72E-04 126 87 20 22.98850575 14 GO:0043169 cation binding 1.14E-08 79 62 2.12E-04 126 87 20 22.98850575 41 GO:0048522 positive regulation of cellular process 1.18E-05 86 56 3.63E-08 103 74 17 22.97297297 37 GO:0048667 cell morphogenesis involved in neuron differentiation 8.26E-09 40 27 9.58E-11 72 61 14 22.95081967 18 GO:0048518 positive regulation of biological process 2.91E-06 237 153 8.37E-12 137 105 24 22.85714286 18 GO:0007275 multicellular organismal development 7.12E-06 371 248 1.33E-06 423 276 63 22.82608696 37 GO:0007610 behavior 1.46E-08 86 57 5.12E-28 273 184 42 22.82608696 41 GO:0018130 heterocycle biosynthetic process 2.35E-07 109 78 2.49E-05 182 114 26 22.80701754 5 GO:0045934 negative regulation of nucleobase-containing compound metabolic process 1.30E-05 46 28 4.71E-07 32 22 5 22.72727273 11 GO:0045138 nematode male tail tip morphogenesis 4.83E-04 7 5 3.90E-07 35 22 5 22.72727273 37 GO:0001708 cell fate specification 4.98E-04 19 13 5.94E-12 67 44 10 22.72727273 37 GO:0061564 axon development 1.49E-08 38 27 1.41E-09 93 66 15 22.72727273 37 GO:0060322 head development 8.38E-07 28 16 3.91E-05 22 22 5 22.72727273 37 GO:0019904 protein domain specific binding 5.69E-05 21 14 1.44E-03 26 22 5 22.72727273 41 GO:0051171 regulation of nitrogen compound metabolic process 1.29E-09 98 73 9.38E-09 172 110 25 22.72727273 41 GO:0009889 regulation of biosynthetic process 4.65E-10 98 72 2.40E-08 176 110 25 22.72727273 41 GO:0031326 regulation of cellular biosynthetic process 3.37E-10 98 72 2.65E-08 175 110 25 22.72727273 41 GO:0009888 tissue development 5.99E-07 80 55 5.18E-08 57 44 10 22.72727273 41 GO:0051172 negative regulation of nitrogen compound metabolic process 3.31E-06 31 22 9.18E-06 34 22 5 22.72727273 5 GO:0003006 developmental process involved in reproduction 2.18E-03 171 103 1.95E-05 184 119 27 22.68907563 37 GO:0019098 reproductive behavior 4.34E-04 48 32 3.41E-18 192 119 27 22.68907563 14 GO:0048731 system development 1.79E-06 113 80 1.84E-13 144 106 24 22.64150943 14 GO:0048513 organ development 1.74E-05 93 64 1.35E-09 113 84 19 22.61904762 41 GO:0044271 cellular nitrogen compound biosynthetic process 2.67E-07 110 78 1.22E-05 185 115 26 22.60869565 41 GO:1901362 organic cyclic compound biosynthetic process 1.15E-06 109 78 5.77E-05 183 115 26 22.60869565 18 GO:0044707 single-multicellular organism process 3.30E-07 398 267 4.85E-07 452 297 67 22.55892256 14 GO:0009605 response to external stimulus 8.03E-06 36 26 4.83E-10 49 40 9 22.5 37 GO:0031327 negative regulation of cellular biosynthetic process 6.22E-08 39 25 1.61E-07 60 40 9 22.5 37 GO:0009890 negative regulation of biosynthetic process 8.61E-08 39 25 2.78E-07 60 40 9 22.5 14 GO:0003677 DNA binding 3.14E-05 49 38 1.27E-03 69 49 11 22.44897959 18 GO:0048699 generation of neurons 4.16E-13 74 55 6.38E-16 72 58 13 22.4137931 37 GO:0007409 axonogenesis 7.47E-08 35 25 1.13E-10 69 58 13 22.4137931 37 GO:0000904 cell morphogenesis involved in differentiation 2.50E-08 44 29 4.13E-12 79 67 15 22.3880597 37 GO:0060255 regulation of macromolecule metabolic process 8.93E-09 143 94 3.61E-09 404 256 57 22.265625 18 GO:0048856 anatomical structure development 5.48E-06 354 235 2.09E-07 393 265 59 22.26415094 3 GO:0034765 regulation of ion transmembrane transport 3.50E-07 7 5 3.28E-06 14 9 2 22.22222222 3 GO:0034762 regulation of transmembrane transport 3.50E-07 7 5 3.28E-06 14 9 2 22.22222222 3 GO:0009952 anterior/posterior pattern specification 2.35E-04 9 7 7.40E-04 15 9 2 22.22222222 4 GO:0007369 gastrulation 1.17E-03 13 8 1.02E-04 16 9 2 22.22222222 5 GO:0043269 regulation of ion transport 2.11E-03 15 7 1.11E-04 17 9 2 22.22222222 11 GO:0046661 male sex differentiation 3.66E-06 11 6 6.89E-08 41 27 6 22.22222222 14 GO:0060284 regulation of cell development 1.21E-05 17 15 1.23E-10 20 18 4 22.22222222 14 GO:0048598 embryonic morphogenesis 1.69E-04 30 22 5.06E-07 27 18 4 22.22222222 18 GO:0030182 neuron differentiation 3.81E-12 68 50 7.49E-15 67 54 12 22.22222222 18 GO:0050795 regulation of behavior 8.93E-05 22 19 3.36E-05 21 18 4 22.22222222 18 GO:0023061 signal release 3.50E-06 20 15 3.26E-04 12 9 2 22.22222222 18 GO:0035239 tube morphogenesis 1.12E-06 30 19 4.56E-04 12 9 2 22.22222222 31 GO:0044212 transcription regulatory region DNA binding 9.96E-10 24 16 5.65E-09 29 18 4 22.22222222 31 GO:0000975 regulatory region DNA binding 2.97E-10 25 17 7.70E-09 29 18 4 22.22222222 31 GO:0001067 regulatory region nucleic acid binding 2.97E-10 25 17 7.70E-09 29 18 4 22.22222222 31 GO:0007271 "synaptic transmission, cholinergic" 1.03E-04 9 5 1.75E-04 11 9 2 22.22222222 31 GO:0030855 epithelial cell differentiation 1.08E-03 17 7 3.86E-04 14 9 2 22.22222222 31 GO:0010467 gene expression 1.24E-04 124 83 1.16E-03 216 144 32 22.22222222 37 GO:0015629 actin cytoskeleton 6.26E-04 20 9 2.82E-09 51 27 6 22.22222222 37 GO:0051172 negative regulation of nitrogen compound metabolic process 3.19E-08 39 26 1.34E-06 55 36 8 22.22222222 37 GO:0034702 ion channel complex 1.93E-03 9 6 7.38E-06 27 18 4 22.22222222 41 GO:1902680 positive regulation of RNA biosynthetic process 8.03E-05 35 24 7.76E-06 37 27 6 22.22222222 41 GO:1903508 positive regulation of nucleic acid-templated transcription 1.63E-05 35 24 1.25E-05 36 27 6 22.22222222 41 GO:0045893 "positive regulation of transcription, DNA-templated" 1.63E-05 35 24 1.25E-05 36 27 6 22.22222222 41 GO:0006836 neurotransmitter transport 1.66E-05 15 12 5.65E-05 21 18 4 22.22222222 41 GO:0001709 cell fate determination 8.68E-04 10 6 8.28E-05 15 9 2 22.22222222 31 GO:0031323 regulation of cellular metabolic process 8.33E-11 121 82 1.51E-07 205 131 29 22.13740458 18 GO:0032502 developmental process 1.53E-06 402 269 3.72E-07 459 303 67 22.11221122 41 GO:0016070 RNA metabolic process 9.82E-04 106 78 4.46E-05 200 127 28 22.04724409 18 GO:0022008 neurogenesis 3.37E-10 75 56 3.07E-15 73 59 13 22.03389831 37 GO:0048699 generation of neurons 2.04E-11 70 46 5.16E-17 153 118 26 22.03389831 31 GO:0040012 regulation of locomotion 8.82E-10 47 37 6.82E-09 48 41 9 21.95121951 18 GO:0007610 behavior 4.52E-09 88 65 6.73E-14 101 73 16 21.91780822 14 GO:0009653 anatomical structure morphogenesis 1.05E-09 115 81 7.42E-13 127 96 21 21.875 14 GO:0043565 sequence-specific DNA binding 3.50E-06 30 24 5.52E-04 44 32 7 21.875 37 GO:0048812 neuron projection morphogenesis 2.69E-08 39 26 1.45E-11 75 64 14 21.875 41 GO:0010628 positive regulation of gene expression 8.53E-06 40 26 3.68E-07 44 32 7 21.875 41 GO:0048598 embryonic morphogenesis 8.34E-06 44 27 5.05E-07 47 32 7 21.875 41 GO:0051094 positive regulation of developmental process 3.59E-04 47 31 1.07E-05 93 64 14 21.875 18 GO:0044767 single-organism developmental process 4.32E-06 391 261 3.67E-07 457 302 66 21.85430464 37 GO:0044705 multi-organism reproductive behavior 6.94E-04 47 31 3.41E-18 192 119 26 21.8487395 37 GO:0051705 multi-organism behavior 3.84E-04 49 31 7.10E-18 192 119 26 21.8487395 41 GO:0007610 behavior 2.21E-09 78 56 2.75E-19 158 119 26 21.8487395 3 GO:0044708 single-organism behavior 4.32E-04 12 9 6.57E-06 29 23 5 21.73913043 5 GO:0051172 negative regulation of nitrogen compound metabolic process 6.89E-06 48 29 2.98E-07 33 23 5 21.73913043 11 GO:0090598 male anatomical structure morphogenesis 1.18E-04 8 5 1.65E-07 36 23 5 21.73913043 31 GO:0034645 cellular macromolecule biosynthetic process 2.97E-06 123 83 3.98E-04 208 138 30 21.73913043 41 GO:0032879 regulation of localization 8.11E-05 40 36 4.68E-07 58 46 10 21.73913043 14 GO:0003676 nucleic acid binding 2.34E-04 75 57 4.73E-04 113 83 18 21.68674699 37 GO:0031175 neuron projection development 5.18E-09 46 31 8.67E-12 112 83 18 21.68674699 37 GO:0044706 multi-multicellular organism process 1.42E-03 47 30 4.36E-18 192 120 26 21.66666667 31 GO:0080090 regulation of primary metabolic process 1.47E-11 120 81 4.24E-09 206 134 29 21.64179104 31 GO:0060255 regulation of macromolecule metabolic process 8.61E-11 124 82 4.91E-07 217 139 30 21.58273381 31 GO:0009059 macromolecule biosynthetic process 5.58E-07 127 85 4.00E-04 210 139 30 21.58273381 18 GO:0033057 multicellular organismal reproductive behavior 1.87E-03 45 33 8.79E-11 74 51 11 21.56862745 18 GO:2000026 regulation of multicellular organismal development 7.23E-08 63 47 3.67E-10 64 51 11 21.56862745 14 GO:0007610 behavior 2.38E-07 54 41 1.59E-14 80 65 14 21.53846154 37 GO:0030029 actin filament-based process 1.18E-06 36 22 3.55E-06 103 65 14 21.53846154 41 GO:0097159 organic cyclic compound binding 3.52E-08 210 149 6.22E-09 459 274 59 21.53284672 18 GO:0040011 locomotion 4.55E-18 222 146 7.92E-16 227 158 34 21.51898734 31 GO:0097159 organic cyclic compound binding 6.46E-06 186 126 8.03E-06 425 270 58 21.48148148 3 GO:0003002 regionalization 2.96E-04 12 10 2.78E-05 22 14 3 21.42857143 14 GO:0007389 pattern specification process 3.58E-04 20 16 7.89E-05 18 14 3 21.42857143 18 GO:0035556 intracellular signal transduction 2.83E-07 72 49 2.46E-09 72 56 12 21.42857143 18 GO:0045664 regulation of neuron differentiation 4.42E-06 20 15 1.24E-06 15 14 3 21.42857143 21 GO:0009887 organ morphogenesis 4.24E-06 17 11 3.37E-04 16 14 3 21.42857143 31 GO:0009888 tissue development 3.74E-10 85 54 3.38E-10 61 42 9 21.42857143 31 GO:0000122 negative regulation of transcription from RNA polymerase II promoter 3.89E-09 25 15 5.01E-07 27 14 3 21.42857143 31 GO:0005634 nucleus 4.10E-04 133 98 9.16E-06 269 182 39 21.42857143 31 GO:0040017 positive regulation of locomotion 1.46E-03 22 15 1.38E-05 17 14 3 21.42857143 37 GO:0003002 regionalization 5.20E-07 29 19 1.15E-06 39 28 6 21.42857143 37 GO:0007167 enzyme linked receptor protein signaling pathway 3.73E-05 31 21 1.07E-04 44 28 6 21.42857143 41 GO:0044708 single-organism behavior 1.37E-04 22 17 3.98E-07 34 28 6 21.42857143 41 GO:0051254 positive regulation of RNA metabolic process 7.08E-05 36 25 2.55E-06 39 28 6 21.42857143 41 GO:1901363 heterocyclic compound binding 4.32E-08 209 148 1.09E-08 456 271 58 21.40221402 37 GO:0006928 movement of cell or subcellular component 3.03E-08 71 51 1.55E-11 178 131 28 21.3740458 37 GO:0034645 cellular macromolecule biosynthetic process 1.83E-04 142 96 3.92E-05 394 262 56 21.3740458 31 GO:1901363 heterocyclic compound binding 7.89E-06 185 125 1.27E-05 422 267 57 21.34831461 37 GO:0009653 anatomical structure morphogenesis 3.80E-12 191 127 2.29E-20 458 296 63 21.28378378 41 GO:0006366 transcription from RNA polymerase II promoter 8.02E-05 47 35 4.06E-08 68 47 10 21.27659574 18 GO:0022414 reproductive process 1.27E-05 157 106 4.12E-05 173 113 24 21.23893805 37 GO:0022603 regulation of anatomical structure morphogenesis 3.01E-06 29 19 1.62E-06 39 33 7 21.21212121 5 GO:1902578 single-organism localization 4.52E-04 187 112 1.17E-04 186 118 25 21.18644068 18 GO:0019098 reproductive behavior 1.66E-03 46 34 4.53E-11 75 52 11 21.15384615 18 GO:0044705 multi-organism reproductive behavior 1.46E-03 46 34 4.53E-11 75 52 11 21.15384615 18 GO:0044706 multi-multicellular organism process 9.46E-04 48 36 4.99E-11 75 52 11 21.15384615 18 GO:0051705 multi-organism behavior 1.47E-03 47 34 6.03E-11 75 52 11 21.15384615 18 GO:0048522 positive regulation of cellular process 3.16E-06 102 63 4.46E-07 68 52 11 21.15384615 37 GO:0009059 macromolecule biosynthetic process 1.91E-04 143 97 2.93E-05 399 265 56 21.13207547 18 GO:0051960 regulation of nervous system development 2.75E-06 25 17 2.20E-09 21 19 4 21.05263158 18 GO:0060284 regulation of cell development 3.33E-06 25 18 1.51E-08 21 19 4 21.05263158 37 GO:0048666 neuron development 2.26E-10 55 36 7.13E-14 125 95 20 21.05263158 37 GO:0010975 regulation of neuron projection development 1.02E-03 12 7 7.54E-06 20 19 4 21.05263158 41 GO:0006928 movement of cell or subcellular component 5.84E-08 62 47 4.71E-08 100 76 16 21.05263158 41 GO:0050793 regulation of developmental process 8.67E-06 87 64 5.06E-13 171 119 25 21.00840336 31 GO:0046872 metal ion binding 4.95E-08 97 76 4.27E-06 279 181 38 20.99447514 31 GO:0045165 cell fate commitment 1.11E-09 37 27 1.29E-13 60 43 9 20.93023256 37 GO:0042221 response to chemical 1.36E-10 109 72 1.73E-05 251 172 36 20.93023256 5 GO:0044765 single-organism transport 8.27E-04 177 107 1.23E-03 169 110 23 20.90909091 18 GO:0044699 single-organism process 4.38E-10 571 391 1.18E-08 665 445 93 20.8988764 14 GO:1901363 heterocyclic compound binding 3.39E-04 131 90 6.76E-06 198 134 28 20.89552239 41 GO:0051240 positive regulation of multicellular organismal process 2.75E-04 48 33 1.47E-05 99 67 14 20.89552239 31 GO:0043169 cation binding 1.63E-07 97 76 3.24E-06 281 182 38 20.87912088 37 GO:0016477 cell migration 2.21E-06 50 36 1.18E-10 133 91 19 20.87912088 4 GO:0048598 embryonic morphogenesis 1.10E-04 24 18 5.24E-08 39 24 5 20.83333333 5 GO:0038023 signaling receptor activity 6.45E-06 52 38 1.14E-03 96 72 15 20.83333333 31 GO:0051056 regulation of small GTPase mediated signal transduction 2.05E-03 14 10 8.05E-06 32 24 5 20.83333333 14 GO:0043167 ion binding 4.60E-06 114 83 5.51E-05 192 125 26 20.8 37 GO:0022008 neurogenesis 3.56E-09 72 47 7.55E-18 161 125 26 20.8 18 GO:0050896 response to stimulus 8.68E-12 246 178 2.84E-09 247 183 38 20.76502732 14 GO:0097159 organic cyclic compound binding 3.96E-04 131 90 5.72E-06 199 135 28 20.74074074 18 GO:0007264 small GTPase mediated signal transduction 1.73E-04 31 24 6.73E-06 35 29 6 20.68965517 31 GO:0019222 regulation of metabolic process 9.75E-13 144 99 3.93E-10 264 174 36 20.68965517 31 GO:0009887 organ morphogenesis 9.56E-11 49 29 4.06E-07 36 29 6 20.68965517 37 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity 6.31E-06 19 12 2.14E-11 43 29 6 20.68965517 41 GO:0045935 positive regulation of nucleobase-containing compound metabolic process 2.42E-05 39 26 5.47E-06 40 29 6 20.68965517 14 GO:0040011 locomotion 5.38E-11 125 85 1.34E-11 157 121 25 20.66115702 37 GO:0051674 localization of cell 1.20E-06 52 37 3.51E-10 134 92 19 20.65217391 37 GO:0048870 cell motility 2.48E-06 51 37 3.51E-10 134 92 19 20.65217391 37 GO:0019222 regulation of metabolic process 2.61E-10 166 110 4.57E-13 486 315 65 20.63492063 37 GO:0006935 chemotaxis 2.01E-09 39 29 1.76E-09 75 63 13 20.63492063 37 GO:0030030 cell projection organization 1.03E-08 57 38 8.95E-12 129 97 20 20.6185567 18 GO:0007165 signal transduction 5.41E-16 165 116 1.14E-08 175 131 27 20.61068702 5 GO:0010171 body morphogenesis 4.61E-04 102 58 6.21E-06 109 68 14 20.58823529 37 GO:0050767 regulation of neurogenesis 1.33E-05 21 13 7.64E-12 37 34 7 20.58823529 41 GO:2000026 regulation of multicellular organismal development 2.63E-09 59 43 9.73E-09 86 68 14 20.58823529 18 GO:0044700 single organism signaling 2.93E-20 194 138 2.26E-09 187 141 29 20.56737589 18 GO:0023052 signaling 1.69E-20 197 141 2.36E-09 187 141 29 20.56737589 37 GO:0030182 neuron differentiation 5.19E-10 63 42 6.39E-17 145 112 23 20.53571429 37 GO:0044249 cellular biosynthetic process 3.54E-04 173 116 1.26E-05 486 322 66 20.49689441 37 GO:0009888 tissue development 1.14E-07 94 59 5.57E-16 109 83 17 20.48192771 14 GO:0006355 "regulation of transcription, DNA-templated" 1.55E-06 56 45 1.10E-05 73 54 11 20.37037037 14 GO:1903506 regulation of nucleic acid-templated transcription 1.55E-06 56 45 1.10E-05 73 54 11 20.37037037 37 GO:1901576 organic substance biosynthetic process 1.62E-03 171 114 1.08E-05 493 324 66 20.37037037 4 GO:0043565 sequence-specific DNA binding 1.04E-13 36 28 2.73E-11 90 59 12 20.33898305 41 GO:0009893 positive regulation of metabolic process 4.01E-07 66 44 8.59E-10 85 59 12 20.33898305 18 GO:0009653 anatomical structure morphogenesis 2.27E-16 206 137 7.38E-17 181 128 26 20.3125 37 GO:0007399 nervous system development 5.49E-08 84 53 3.41E-21 187 143 29 20.27972028 18 GO:0007154 cell communication 2.32E-20 199 143 1.55E-09 190 144 29 20.13888889 41 GO:0022414 reproductive process 1.53E-05 134 94 1.33E-07 286 189 38 20.10582011 5 GO:0051179 localization 1.83E-08 340 218 2.54E-03 366 229 46 20.08733624 18 GO:0009987 cellular process 1.06E-05 516 353 4.75E-12 585 399 80 20.05012531 4 GO:0031672 A band 1.19E-04 7 5 1.85E-03 8 5 1 20 5 GO:0000976 transcription regulatory region sequence-specific DNA binding 1.07E-07 23 15 1.42E-07 21 15 3 20 14 GO:0031672 A band 1.69E-04 8 5 7.10E-07 10 5 1 20 14 GO:2001141 regulation of RNA biosynthetic process 3.98E-06 56 45 7.09E-06 74 55 11 20 14 GO:0003006 developmental process involved in reproduction 5.32E-04 69 47 4.40E-05 102 70 14 20 18 GO:0007166 cell surface receptor signaling pathway 2.87E-10 86 59 3.14E-05 70 55 11 20 18 GO:0007267 cell-cell signaling 1.37E-06 43 31 1.16E-04 27 20 4 20 21 GO:0030016 myofibril 4.50E-04 7 4 9.91E-05 14 5 1 20 21 GO:0030017 sarcomere 2.97E-04 7 4 1.42E-04 13 5 1 20 31 GO:0060429 epithelium development 2.39E-08 70 44 7.35E-07 38 25 5 20 31 GO:0010720 positive regulation of cell development 4.96E-04 9 5 2.00E-06 10 10 2 20 31 GO:0008134 transcription factor binding 5.70E-05 22 18 1.03E-03 21 15 3 20 37 GO:0045664 regulation of neuron differentiation 5.62E-05 18 11 1.38E-10 33 30 6 20 37 GO:0042330 taxis 1.99E-08 40 30 1.22E-09 79 65 13 20 37 GO:0060429 epithelium development 3.16E-06 77 47 1.44E-09 66 50 10 20 37 GO:0009605 response to external stimulus 1.38E-12 71 46 1.73E-09 138 105 21 20 37 GO:0060562 epithelial tube morphogenesis 3.09E-05 23 16 1.72E-05 18 15 3 20 41 GO:0051960 regulation of nervous system development 8.45E-08 25 14 1.50E-09 27 25 5 20 41 GO:0051173 positive regulation of nitrogen compound metabolic process 1.01E-05 41 27 1.57E-06 42 30 6 20 41 GO:0007269 neurotransmitter secretion 4.51E-05 13 10 6.26E-05 16 15 3 20 41 GO:0001012 RNA polymerase II regulatory region DNA binding 5.44E-05 8 6 1.09E-04 15 10 2 20 41 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding 5.44E-05 8 6 3.34E-04 13 10 2 20 41 GO:0048582 positive regulation of post-embryonic development 1.90E-03 7 7 1.95E-03 16 15 3 20 41 GO:0061063 positive regulation of nematode larval development 1.90E-03 7 7 1.95E-03 16 15 3 20 37 GO:0009058 biosynthetic process 1.14E-03 177 117 1.81E-05 501 331 66 19.93957704 31 GO:0005488 binding 3.37E-06 350 243 9.02E-12 773 494 98 19.83805668 37 GO:0000902 cell morphogenesis 3.15E-07 52 34 1.09E-11 102 86 17 19.76744186 37 GO:0030054 cell junction 1.70E-04 35 20 3.82E-19 105 76 15 19.73684211 14 GO:0048609 multicellular organismal reproductive process 1.62E-05 59 41 4.81E-09 94 71 14 19.71830986 37 GO:0050794 regulation of cellular process 4.23E-21 311 216 2.34E-45 949 645 127 19.68992248 37 GO:0005216 ion channel activity 2.14E-03 35 21 1.89E-07 102 61 12 19.67213115 31 GO:0009653 anatomical structure morphogenesis 3.62E-12 157 108 3.52E-15 253 163 32 19.63190184 14 GO:0042221 response to chemical 1.29E-04 55 39 2.64E-05 70 51 10 19.60784314 37 GO:0045935 positive regulation of nucleobase-containing compound metabolic process 5.98E-05 43 28 4.50E-09 71 51 10 19.60784314 37 GO:0051173 positive regulation of nitrogen compound metabolic process 6.42E-05 44 28 5.48E-09 72 51 10 19.60784314 41 GO:0048513 organ development 1.72E-07 139 91 5.67E-06 208 143 28 19.58041958 18 GO:0051716 cellular response to stimulus 8.31E-10 175 123 1.94E-06 184 138 27 19.56521739 18 GO:0051094 positive regulation of developmental process 4.08E-06 61 39 4.04E-05 61 46 9 19.56521739 18 GO:0048513 organ development 1.60E-09 170 108 4.99E-05 131 92 18 19.56521739 41 GO:0006357 regulation of transcription from RNA polymerase II promoter 9.44E-06 43 33 6.00E-10 67 46 9 19.56521739 14 GO:0032989 cellular component morphogenesis 2.16E-04 33 24 8.87E-09 54 41 8 19.51219512 31 GO:0098772 molecular function regulator 1.78E-03 24 19 5.13E-05 55 41 8 19.51219512 37 GO:0005634 nucleus 2.04E-03 161 114 1.99E-06 500 323 63 19.50464396 37 GO:0048522 positive regulation of cellular process 9.21E-05 95 59 6.22E-10 177 118 23 19.49152542 37 GO:0007264 small GTPase mediated signal transduction 7.63E-04 29 21 4.19E-13 99 77 15 19.48051948 18 GO:0043167 ion binding 1.18E-04 179 130 4.07E-07 283 185 36 19.45945946 31 GO:0035556 intracellular signal transduction 2.27E-05 54 34 2.83E-07 94 72 14 19.44444444 37 GO:0048858 cell projection morphogenesis 3.45E-06 39 26 3.95E-10 85 72 14 19.44444444 37 GO:0032990 cell part morphogenesis 6.36E-06 39 26 2.00E-09 85 72 14 19.44444444 37 GO:0002009 morphogenesis of an epithelium 6.10E-05 61 40 6.10E-07 44 36 7 19.44444444 41 GO:0032501 multicellular organismal process 3.95E-04 332 237 2.42E-06 738 468 91 19.44444444 41 GO:0034645 cellular macromolecule biosynthetic process 8.94E-04 118 87 5.27E-05 220 144 28 19.44444444 41 GO:0031323 regulation of cellular metabolic process 2.13E-08 120 87 2.26E-09 219 139 27 19.42446043 41 GO:0005488 binding 5.23E-07 380 277 1.25E-13 805 510 99 19.41176471 14 GO:0034654 nucleobase-containing compound biosynthetic process 3.57E-04 66 51 1.20E-05 86 67 13 19.40298507 14 GO:0044271 cellular nitrogen compound biosynthetic process 5.45E-04 68 52 2.20E-05 88 67 13 19.40298507 14 GO:0019438 aromatic compound biosynthetic process 5.09E-04 67 52 3.24E-05 86 67 13 19.40298507 37 GO:0048646 anatomical structure formation involved in morphogenesis 1.41E-06 49 30 7.17E-04 114 67 13 19.40298507 18 GO:0006935 chemotaxis 1.86E-10 41 32 3.33E-10 38 31 6 19.35483871 18 GO:0042330 taxis 6.76E-10 43 34 2.21E-09 38 31 6 19.35483871 14 GO:0006351 "transcription, DNA-templated" 5.38E-05 60 47 1.12E-05 76 57 11 19.29824561 14 GO:0097659 nucleic acid-templated transcription 5.38E-05 60 47 1.37E-05 76 57 11 19.29824561 41 GO:0080090 regulation of primary metabolic process 1.67E-08 117 85 3.26E-10 216 140 27 19.28571429 37 GO:0050789 regulation of biological process 2.19E-12 405 273 2.91E-44 1127 753 145 19.2563081 14 GO:0045595 regulation of cell differentiation 2.80E-04 23 19 3.35E-10 28 26 5 19.23076923 18 GO:0007411 axon guidance 2.46E-10 32 26 1.27E-09 30 26 5 19.23076923 18 GO:0097485 neuron projection guidance 6.82E-11 33 27 1.55E-09 30 26 5 19.23076923 37 GO:0009891 positive regulation of biosynthetic process 3.02E-05 45 28 3.94E-10 75 52 10 19.23076923 37 GO:0031328 positive regulation of cellular biosynthetic process 2.50E-05 45 28 3.94E-10 75 52 10 19.23076923 41 GO:0045944 positive regulation of transcription from RNA polymerase II promoter 4.61E-04 25 18 1.15E-06 35 26 5 19.23076923 31 GO:0009058 biosynthetic process 2.66E-05 151 100 2.00E-03 255 172 33 19.18604651 14 GO:0032504 multicellular organism reproduction 2.21E-05 59 41 1.40E-09 96 73 14 19.17808219 41 GO:0009059 macromolecule biosynthetic process 8.69E-04 119 88 3.90E-05 223 146 28 19.17808219 37 GO:0048731 system development 8.44E-08 190 124 1.84E-17 509 334 64 19.16167665 18 GO:0048666 neuron development 2.62E-09 53 41 3.55E-13 59 47 9 19.14893617 37 GO:0005887 integral component of plasma membrane 7.91E-05 23 15 1.57E-12 63 47 9 19.14893617 5 GO:0044425 membrane part 5.82E-08 249 158 6.56E-05 300 209 40 19.13875598 4 GO:0007389 pattern specification process 8.83E-06 19 17 7.60E-07 29 21 4 19.04761905 5 GO:0035295 tube development 3.46E-04 46 28 1.09E-03 30 21 4 19.04761905 31 GO:2000113 negative regulation of cellular macromolecule biosynthetic process 2.05E-08 34 23 7.27E-07 37 21 4 19.04761905 31 GO:0010558 negative regulation of macromolecule biosynthetic process 2.77E-08 34 23 7.27E-07 37 21 4 19.04761905 31 GO:0044249 cellular biosynthetic process 2.49E-06 150 99 8.74E-04 250 168 32 19.04761905 31 GO:1901576 organic substance biosynthetic process 1.78E-05 148 98 1.54E-03 251 168 32 19.04761905 37 GO:0060284 regulation of cell development 2.90E-06 25 16 1.43E-13 46 42 8 19.04761905 37 GO:0007420 brain development 1.95E-06 27 15 9.11E-05 21 21 4 19.04761905 41 GO:0045202 synapse 3.01E-05 33 26 1.58E-09 52 42 8 19.04761905 41 GO:0060255 regulation of macromolecule metabolic process 1.25E-08 124 91 1.17E-08 231 147 28 19.04761905 31 GO:0032501 multicellular organismal process 4.42E-05 316 216 2.27E-05 709 458 87 18.99563319 18 GO:0048468 cell development 7.84E-08 98 71 9.33E-06 108 79 15 18.98734177 41 GO:0050789 regulation of biological process 6.37E-09 332 241 3.08E-33 631 427 81 18.96955504 4 GO:0048518 positive regulation of biological process 3.29E-05 102 76 3.28E-14 159 116 22 18.96551724 14 GO:0032774 RNA biosynthetic process 1.01E-04 60 47 1.14E-05 77 58 11 18.96551724 37 GO:0030036 actin cytoskeleton organization 2.90E-05 31 19 8.13E-05 94 58 11 18.96551724 31 GO:0022803 passive transmembrane transporter activity 1.43E-03 32 24 1.91E-05 62 37 7 18.91891892 31 GO:0015267 channel activity 1.43E-03 32 24 1.91E-05 62 37 7 18.91891892 41 GO:0044707 single-multicellular organism process 1.57E-03 312 224 1.31E-05 709 450 85 18.88888889 41 GO:0030154 cell differentiation 3.56E-09 116 82 1.95E-08 210 143 27 18.88111888 41 GO:0048731 system development 1.74E-08 167 112 7.35E-10 270 191 36 18.84816754 37 GO:0048513 organ development 1.02E-06 157 101 2.81E-11 400 260 49 18.84615385 31 GO:0007275 multicellular organismal development 1.12E-04 285 191 3.70E-04 633 404 76 18.81188119 41 GO:0051239 regulation of multicellular organismal process 9.43E-06 90 66 1.65E-14 189 133 25 18.79699248 11 GO:0010172 embryonic body morphogenesis 9.58E-04 7 5 2.17E-05 25 16 3 18.75 18 GO:0000904 cell morphogenesis involved in differentiation 3.35E-10 48 34 1.20E-10 38 32 6 18.75 18 GO:0007631 feeding behavior 5.61E-04 18 14 5.67E-07 22 16 3 18.75 18 GO:0051240 positive regulation of multicellular organismal process 7.47E-07 64 41 7.98E-05 64 48 9 18.75 41 GO:0030054 cell junction 4.09E-06 35 23 8.18E-13 62 48 9 18.75 41 GO:0000976 transcription regulatory region sequence-specific DNA binding 4.20E-08 17 13 9.54E-07 22 16 3 18.75 41 GO:0044212 transcription regulatory region DNA binding 4.59E-09 24 17 2.67E-06 25 16 3 18.75 41 GO:0000975 regulatory region DNA binding 1.47E-09 25 18 3.39E-06 25 16 3 18.75 41 GO:0001067 regulatory region nucleic acid binding 1.47E-09 25 18 3.39E-06 25 16 3 18.75 41 GO:0023061 signal release 9.00E-07 19 14 1.01E-04 17 16 3 18.75 41 GO:0001505 regulation of neurotransmitter levels 5.54E-05 16 13 2.25E-04 18 16 3 18.75 41 GO:0046872 metal ion binding 3.01E-07 100 79 5.96E-10 309 198 37 18.68686869 41 GO:0043169 cation binding 5.21E-07 101 80 6.70E-10 310 198 37 18.68686869 37 GO:0065007 biological regulation 2.40E-12 417 282 1.07E-28 1257 803 150 18.67995019 14 GO:0044703 multi-organism reproductive process 2.45E-05 60 42 3.03E-10 101 75 14 18.66666667 4 GO:0044706 multi-multicellular organism process 7.56E-04 24 20 1.22E-10 81 59 11 18.6440678 14 GO:0051252 regulation of RNA metabolic process 6.21E-06 58 46 9.01E-07 78 59 11 18.6440678 14 GO:2000112 regulation of cellular macromolecule biosynthetic process 3.12E-05 57 46 6.86E-06 79 59 11 18.6440678 18 GO:0048583 regulation of response to stimulus 8.56E-09 84 61 8.01E-11 75 59 11 18.6440678 37 GO:0036477 somatodendritic compartment 1.91E-03 24 20 3.32E-08 73 59 11 18.6440678 37 GO:0035295 tube development 1.97E-05 35 24 1.42E-05 64 43 8 18.60465116 37 GO:0097458 neuron part 1.49E-04 42 30 1.19E-18 137 113 21 18.5840708 5 GO:0044877 macromolecular complex binding 8.44E-04 45 28 2.13E-05 34 27 5 18.51851852 5 GO:0098662 inorganic cation transmembrane transport 1.54E-03 29 18 2.30E-04 40 27 5 18.51851852 5 GO:0098655 cation transmembrane transport 1.78E-03 29 18 2.30E-04 40 27 5 18.51851852 18 GO:0097458 neuron part 3.62E-06 47 36 9.50E-16 64 54 10 18.51851852 37 GO:0097159 organic cyclic compound binding 5.25E-07 238 161 8.22E-11 839 519 96 18.49710983 31 GO:0044707 single-multicellular organism process 4.45E-05 302 205 1.22E-04 680 438 81 18.49315068 41 GO:0005634 nucleus 1.73E-03 138 100 3.41E-05 272 184 34 18.47826087 14 GO:0005488 binding 1.24E-05 256 178 2.49E-09 348 244 45 18.44262295 41 GO:0019222 regulation of metabolic process 2.69E-09 141 104 9.78E-12 278 179 33 18.43575419 14 GO:0032501 multicellular organismal process 1.21E-04 231 164 3.81E-07 330 228 42 18.42105263 37 GO:1901363 heterocyclic compound binding 1.39E-06 235 159 8.98E-11 836 516 95 18.41085271 37 GO:0007275 multicellular organismal development 7.53E-04 353 244 6.31E-04 1210 745 137 18.38926174 37 GO:0051254 positive regulation of RNA metabolic process 6.16E-05 41 27 1.16E-09 69 49 9 18.36734694 31 GO:0007548 sex differentiation 1.04E-03 70 43 5.85E-06 164 109 20 18.34862385 14 GO:0010556 regulation of macromolecule biosynthetic process 4.11E-05 58 46 4.94E-06 80 60 11 18.33333333 41 GO:0050794 regulation of cellular process 6.03E-16 255 189 2.79E-30 525 360 66 18.33333333 18 GO:0044763 single-organism cellular process 1.26E-11 401 283 9.33E-13 482 334 61 18.26347305 37 GO:0004872 receptor activity 8.92E-11 65 47 3.18E-05 222 148 27 18.24324324 37 GO:0005488 binding 4.70E-06 441 297 7.39E-17 1487 940 171 18.19148936 4 GO:0009887 organ morphogenesis 1.41E-06 26 19 1.70E-05 26 22 4 18.18181818 5 GO:0007423 sensory organ development 5.32E-04 34 18 2.86E-03 12 11 2 18.18181818 11 GO:2000113 negative regulation of cellular macromolecule biosynthetic process 1.55E-05 18 15 8.43E-07 54 33 6 18.18181818 11 GO:0010558 negative regulation of macromolecule biosynthetic process 1.82E-05 18 15 8.43E-07 54 33 6 18.18181818 11 GO:0000122 negative regulation of transcription from RNA polymerase II promoter 1.41E-05 13 10 5.08E-06 36 22 4 18.18181818 18 GO:0032940 secretion by cell 5.43E-04 22 17 1.22E-04 30 22 4 18.18181818 18 GO:0005911 cell-cell junction 6.80E-05 19 14 1.61E-04 14 11 2 18.18181818 31 GO:0009893 positive regulation of metabolic process 3.78E-09 68 47 4.64E-10 84 55 10 18.18181818 31 GO:0007267 cell-cell signaling 1.72E-06 36 25 4.79E-08 46 33 6 18.18181818 31 GO:0045597 positive regulation of cell differentiation 5.27E-06 16 8 5.67E-05 11 11 2 18.18181818 31 GO:0035239 tube morphogenesis 8.72E-06 24 13 1.19E-03 15 11 2 18.18181818 37 GO:0010628 positive regulation of gene expression 2.28E-05 44 27 9.62E-11 77 55 10 18.18181818 41 GO:0007411 axon guidance 3.00E-08 26 19 2.84E-09 39 33 6 18.18181818 41 GO:0097485 neuron projection guidance 3.71E-08 26 19 3.63E-09 39 33 6 18.18181818 37 GO:0022414 reproductive process 4.49E-04 147 97 1.25E-09 520 320 58 18.125 31 GO:0005623 cell 6.86E-06 362 243 3.55E-23 738 497 90 18.10865191 37 GO:0032989 cellular component morphogenesis 1.13E-07 61 39 8.23E-09 164 116 21 18.10344828 37 GO:0040011 locomotion 1.41E-12 203 133 1.44E-25 624 404 73 18.06930693 31 GO:0005622 intracellular 1.04E-03 310 208 2.26E-10 604 410 74 18.04878049 37 GO:0032501 multicellular organismal process 1.05E-03 388 262 4.87E-05 1351 826 149 18.03874092 14 GO:0031326 regulation of cellular biosynthetic process 3.53E-05 59 46 1.69E-06 82 61 11 18.03278689 14 GO:0009889 regulation of biosynthetic process 4.17E-05 59 46 2.11E-06 82 61 11 18.03278689 41 GO:0048869 cellular developmental process 1.71E-07 116 82 6.94E-09 220 150 27 18 14 GO:0030154 cell differentiation 4.08E-06 76 59 5.67E-12 115 89 16 17.97752809 41 GO:0065007 biological regulation 4.30E-09 343 250 6.72E-22 691 451 81 17.96008869 18 GO:0009966 regulation of signal transduction 1.15E-06 59 40 6.61E-07 50 39 7 17.94871795 31 GO:0007264 small GTPase mediated signal transduction 6.41E-05 27 19 7.68E-07 51 39 7 17.94871795 37 GO:0007155 cell adhesion 8.09E-08 30 19 1.34E-08 50 39 7 17.94871795 37 GO:0022610 biological adhesion 8.09E-08 30 19 3.97E-08 50 39 7 17.94871795 41 GO:0007267 cell-cell signaling 3.84E-06 37 29 1.47E-08 48 39 7 17.94871795 41 GO:0048856 anatomical structure development 8.96E-04 284 205 9.13E-07 618 390 70 17.94871795 41 GO:0048699 generation of neurons 1.20E-11 63 42 6.43E-09 81 67 12 17.91044776 14 GO:0044707 single-multicellular organism process 8.05E-05 222 158 1.20E-06 318 218 39 17.88990826 37 GO:0044707 single-multicellular organism process 3.70E-04 374 255 2.27E-04 1299 794 142 17.88413098 5 GO:0098660 inorganic ion transmembrane transport 2.06E-03 29 18 6.47E-04 41 28 5 17.85714286 11 GO:0048598 embryonic morphogenesis 5.43E-06 26 18 6.05E-13 83 56 10 17.85714286 11 GO:1902679 negative regulation of RNA biosynthetic process 4.87E-06 17 14 5.49E-07 45 28 5 17.85714286 11 GO:1903507 negative regulation of nucleic acid-templated transcription 4.42E-06 17 14 5.49E-07 45 28 5 17.85714286 11 GO:0045892 "negative regulation of transcription, DNA-templated" 4.42E-06 17 14 5.49E-07 45 28 5 17.85714286 11 GO:0051253 negative regulation of RNA metabolic process 8.52E-06 17 14 1.70E-06 45 28 5 17.85714286 37 GO:0030017 sarcomere 5.15E-04 16 8 1.03E-11 49 28 5 17.85714286 37 GO:0000976 transcription regulatory region sequence-specific DNA binding 2.98E-06 16 12 8.24E-11 38 28 5 17.85714286 37 GO:0051128 regulation of cellular component organization 5.22E-04 52 29 1.02E-05 110 84 15 17.85714286 41 GO:0007155 cell adhesion 1.57E-05 23 14 1.05E-09 36 28 5 17.85714286 41 GO:0022610 biological adhesion 1.57E-05 23 14 2.39E-09 36 28 5 17.85714286 41 GO:0009968 negative regulation of signal transduction 1.62E-03 19 14 8.60E-08 34 28 5 17.85714286 37 GO:0048856 anatomical structure development 5.03E-04 337 231 2.90E-05 1118 695 124 17.84172662 31 GO:0048856 anatomical structure development 6.09E-04 266 182 3.70E-04 577 376 67 17.81914894 37 GO:0048869 cellular developmental process 1.21E-08 138 88 1.40E-11 395 264 47 17.8030303 37 GO:0030154 cell differentiation 1.16E-08 131 84 2.56E-11 379 253 45 17.78656126 31 GO:0044464 cell part 9.94E-06 360 241 4.79E-23 735 495 88 17.77777778 41 GO:0048583 regulation of response to stimulus 3.39E-08 72 51 3.37E-15 118 90 16 17.77777778 37 GO:0005515 protein binding 2.97E-04 219 143 1.37E-15 586 394 70 17.76649746 31 GO:0043167 ion binding 6.88E-05 144 103 1.06E-07 436 276 49 17.75362319 14 GO:0019219 regulation of nucleobase-containing compound metabolic process 3.11E-05 59 47 5.94E-07 81 62 11 17.74193548 31 GO:2000026 regulation of multicellular organismal development 1.40E-07 52 35 1.10E-07 81 62 11 17.74193548 14 GO:0032502 developmental process 6.10E-04 221 158 3.01E-06 320 220 39 17.72727273 41 GO:0032502 developmental process 1.11E-03 320 227 8.70E-06 721 452 80 17.69911504 37 GO:0032502 developmental process 1.36E-03 377 256 4.12E-04 1315 804 142 17.66169154 3 GO:0001071 nucleic acid binding transcription factor activity 3.10E-12 30 25 1.71E-10 110 68 12 17.64705882 3 GO:0003700 sequence-specific DNA binding transcription factor activity 1.53E-11 29 24 1.71E-10 110 68 12 17.64705882 5 GO:0010629 negative regulation of gene expression 3.47E-04 54 32 2.76E-04 50 34 6 17.64705882 11 GO:0031327 negative regulation of cellular biosynthetic process 1.97E-05 18 15 5.58E-07 55 34 6 17.64705882 11 GO:0009890 negative regulation of biosynthetic process 2.30E-05 18 15 9.09E-07 55 34 6 17.64705882 11 GO:0061061 muscle structure development 4.42E-06 17 12 2.64E-03 81 51 9 17.64705882 31 GO:1902679 negative regulation of RNA biosynthetic process 2.23E-09 32 21 8.19E-07 31 17 3 17.64705882 31 GO:1903507 negative regulation of nucleic acid-templated transcription 1.85E-09 32 21 8.19E-07 31 17 3 17.64705882 31 GO:0045892 "negative regulation of transcription, DNA-templated" 1.85E-09 32 21 8.19E-07 31 17 3 17.64705882 31 GO:0051253 negative regulation of RNA metabolic process 6.56E-09 32 21 1.84E-06 31 17 3 17.64705882 37 GO:0010557 positive regulation of macromolecule biosynthetic process 3.74E-05 43 27 4.59E-10 73 51 9 17.64705882 41 GO:0044767 single-organism developmental process 1.57E-03 312 220 1.02E-05 717 448 79 17.63392857 31 GO:0044767 single-organism developmental process 4.38E-04 295 199 2.22E-04 684 437 77 17.6201373 14 GO:0048869 cellular developmental process 2.57E-05 77 59 9.64E-12 118 91 16 17.58241758 5 GO:0004888 transmembrane signaling receptor activity 6.06E-05 40 30 3.35E-05 70 57 10 17.54385965 31 GO:0040011 locomotion 1.20E-13 170 121 7.33E-16 331 228 40 17.54385965 31 GO:0032502 developmental process 1.12E-03 298 201 2.90E-04 686 439 77 17.53986333 14 GO:0048856 anatomical structure development 3.49E-04 198 141 1.17E-06 276 194 34 17.5257732 37 GO:0050793 regulation of developmental process 1.19E-04 95 62 8.59E-15 289 194 34 17.5257732 11 GO:0001708 cell fate specification 2.46E-04 11 10 2.98E-09 58 40 7 17.5 18 GO:0000902 cell morphogenesis 2.24E-06 50 36 1.92E-10 47 40 7 17.5 37 GO:0051960 regulation of nervous system development 2.40E-06 25 14 3.29E-14 44 40 7 17.5 37 GO:0044767 single-organism developmental process 4.85E-04 373 252 3.29E-04 1310 800 140 17.5 41 GO:0000904 cell morphogenesis involved in differentiation 4.08E-08 39 26 3.13E-09 48 40 7 17.5 41 GO:0006935 chemotaxis 2.78E-09 35 26 1.01E-08 48 40 7 17.5 41 GO:0031325 positive regulation of cellular metabolic process 3.16E-05 54 35 4.37E-06 59 40 7 17.5 31 GO:0050789 regulation of biological process 7.05E-11 319 223 5.37E-37 628 423 74 17.49408983 14 GO:0051171 regulation of nitrogen compound metabolic process 3.73E-05 60 47 2.02E-07 83 63 11 17.46031746 4 GO:2000026 regulation of multicellular organismal development 5.74E-09 36 27 6.96E-06 58 46 8 17.39130435 11 GO:0040012 regulation of locomotion 5.20E-05 22 19 1.93E-18 89 69 12 17.39130435 18 GO:0046903 secretion 1.41E-03 23 17 1.01E-04 31 23 4 17.39130435 31 GO:0031327 negative regulation of cellular biosynthetic process 3.22E-08 34 23 1.21E-07 39 23 4 17.39130435 31 GO:0009890 negative regulation of biosynthetic process 4.32E-08 34 23 1.77E-07 39 23 4 17.39130435 41 GO:0022008 neurogenesis 3.00E-09 64 42 1.50E-08 83 69 12 17.39130435 31 GO:0022414 reproductive process 1.32E-04 121 78 8.29E-08 280 190 33 17.36842105 37 GO:0016043 cellular component organization 1.88E-06 182 120 1.26E-08 516 340 59 17.35294118 14 GO:0044767 single-organism developmental process 3.63E-04 218 156 2.57E-06 319 219 38 17.35159817 31 GO:0005515 protein binding 2.75E-05 181 127 8.69E-14 326 220 38 17.27272727 18 GO:0030424 axon 1.72E-03 22 15 1.40E-11 35 29 5 17.24137931 18 GO:0007409 axonogenesis 2.20E-09 38 29 6.42E-10 34 29 5 17.24137931 41 GO:0009653 anatomical structure morphogenesis 7.52E-11 162 109 2.24E-13 252 174 30 17.24137931 37 GO:0009893 positive regulation of metabolic process 1.43E-04 66 42 1.55E-11 141 99 17 17.17171717 41 GO:0044699 single-organism process 1.49E-05 459 330 9.77E-15 1108 699 120 17.16738197 37 GO:0071840 cellular component organization or biogenesis 7.07E-06 186 123 1.64E-07 525 344 59 17.15116279 18 GO:0048858 cell projection morphogenesis 1.61E-06 40 30 1.92E-09 40 35 6 17.14285714 18 GO:0032990 cell part morphogenesis 3.05E-06 40 30 4.46E-09 40 35 6 17.14285714 18 GO:0071944 cell periphery 2.11E-08 104 59 7.61E-13 109 76 13 17.10526316 4 GO:0009893 positive regulation of metabolic process 1.06E-04 33 25 8.69E-06 55 41 7 17.07317073 18 GO:0031175 neuron projection development 6.61E-09 46 35 1.35E-11 53 41 7 17.07317073 41 GO:0048523 negative regulation of cellular process 9.79E-06 78 52 1.24E-12 119 82 14 17.07317073 41 GO:0007399 nervous system development 9.87E-09 76 48 1.24E-11 101 82 14 17.07317073 41 GO:0031324 negative regulation of cellular metabolic process 3.78E-04 37 26 9.91E-08 63 41 7 17.07317073 37 GO:0035556 intracellular signal transduction 9.52E-05 63 41 2.29E-14 185 135 23 17.03703704 18 GO:0023051 regulation of signaling 1.02E-06 67 45 5.16E-08 58 47 8 17.0212766 18 GO:0010646 regulation of cell communication 1.02E-06 67 45 6.14E-08 58 47 8 17.0212766 37 GO:0043005 neuron projection 1.27E-03 33 22 1.11E-16 113 94 16 17.0212766 37 GO:1902680 positive regulation of RNA biosynthetic process 6.22E-05 40 26 1.85E-09 67 47 8 17.0212766 37 GO:1903508 positive regulation of nucleic acid-templated transcription 1.05E-05 40 26 1.98E-09 66 47 8 17.0212766 37 GO:0045893 "positive regulation of transcription, DNA-templated" 1.05E-05 40 26 1.98E-09 66 47 8 17.0212766 37 GO:0031226 intrinsic component of plasma membrane 4.28E-05 24 15 7.68E-15 69 53 9 16.98113208 37 GO:2000026 regulation of multicellular organismal development 1.27E-07 62 40 8.79E-12 149 112 19 16.96428571 4 GO:0001071 nucleic acid binding transcription factor activity 1.29E-13 34 27 1.19E-09 90 59 10 16.94915254 4 GO:0003700 sequence-specific DNA binding transcription factor activity 1.13E-13 34 27 1.19E-09 90 59 10 16.94915254 37 GO:0023052 signaling 1.42E-17 188 137 1.36E-33 604 425 72 16.94117647 37 GO:0060089 molecular transducer activity 3.77E-11 74 55 2.50E-08 266 183 31 16.93989071 37 GO:0006796 phosphate-containing compound metabolic process 1.25E-04 114 74 3.31E-04 313 201 34 16.91542289 37 GO:0006366 transcription from RNA polymerase II promoter 3.74E-06 58 36 1.36E-13 124 83 14 16.86746988 37 GO:0005886 plasma membrane 5.74E-08 95 54 1.40E-29 283 196 33 16.83673469 41 GO:0060089 molecular transducer activity 1.02E-06 55 39 7.81E-07 150 101 17 16.83168317 37 GO:0007154 cell communication 1.83E-17 190 138 3.01E-33 610 428 72 16.82242991 11 GO:0043565 sequence-specific DNA binding 1.61E-09 29 25 1.20E-09 170 113 19 16.81415929 41 GO:0005515 protein binding 1.07E-03 183 134 3.05E-12 327 238 40 16.80672269 37 GO:0046872 metal ion binding 3.18E-09 122 94 2.10E-11 550 352 59 16.76136364 37 GO:0006793 phosphorus metabolic process 9.36E-05 116 75 4.97E-04 316 203 34 16.74876847 37 GO:0044700 single organism signaling 2.49E-17 185 135 1.14E-33 604 425 71 16.70588235 5 GO:0044212 transcription regulatory region DNA binding 4.40E-07 31 19 1.30E-08 26 18 3 16.66666667 5 GO:0000975 regulatory region DNA binding 6.36E-08 33 21 1.71E-08 26 18 3 16.66666667 5 GO:0001067 regulatory region nucleic acid binding 6.36E-08 33 21 1.71E-08 26 18 3 16.66666667 5 GO:0015085 calcium ion transmembrane transporter activity 5.59E-04 14 9 3.75E-04 10 6 1 16.66666667 5 GO:0043009 chordate embryonic development 2.71E-04 25 14 2.73E-03 8 6 1 16.66666667 11 GO:0045934 negative regulation of nucleobase-containing compound metabolic process 3.28E-05 17 14 2.76E-05 47 30 5 16.66666667 14 GO:0007155 cell adhesion 6.95E-04 15 9 3.99E-05 16 12 2 16.66666667 14 GO:0022610 biological adhesion 6.95E-04 15 9 5.57E-05 16 12 2 16.66666667 18 GO:0048667 cell morphogenesis involved in neuron differentiation 1.03E-08 40 30 7.82E-10 35 30 5 16.66666667 18 GO:0051962 positive regulation of nervous system development 1.56E-05 13 9 3.98E-05 7 6 1 16.66666667 18 GO:0010648 negative regulation of cell communication 4.41E-07 32 22 8.07E-05 21 18 3 16.66666667 18 GO:0023057 negative regulation of signaling 3.70E-07 32 22 8.07E-05 21 18 3 16.66666667 18 GO:0031324 negative regulation of cellular metabolic process 5.06E-04 42 25 1.09E-04 37 24 4 16.66666667 18 GO:0030334 regulation of cell migration 1.42E-05 18 15 3.73E-04 13 12 2 16.66666667 18 GO:2000145 regulation of cell motility 2.22E-05 18 15 4.35E-04 13 12 2 16.66666667 18 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding 1.30E-03 7 5 1.31E-03 9 6 1 16.66666667 31 GO:0001667 ameboidal-type cell migration 5.07E-06 17 13 1.59E-06 16 12 2 16.66666667 31 GO:0050767 regulation of neurogenesis 4.27E-06 19 12 1.81E-06 20 18 3 16.66666667 31 GO:0090066 regulation of anatomical structure size 1.27E-03 14 6 6.07E-06 23 18 3 16.66666667 31 GO:0045934 negative regulation of nucleobase-containing compound metabolic process 8.59E-08 32 21 1.82E-05 32 18 3 16.66666667 31 GO:0002064 epithelial cell development 1.22E-03 11 4 7.97E-04 9 6 1 16.66666667 37 GO:0044459 plasma membrane part 2.25E-05 56 32 1.30E-22 150 108 18 16.66666667 37 GO:0030016 myofibril 3.77E-04 17 9 7.78E-13 54 30 5 16.66666667 37 GO:0031324 negative regulation of cellular metabolic process 2.47E-05 46 30 5.61E-08 101 66 11 16.66666667 37 GO:0007417 central nervous system development 1.10E-05 32 17 1.22E-04 24 24 4 16.66666667 41 GO:0007409 axonogenesis 1.12E-08 33 24 1.01E-08 43 36 6 16.66666667 41 GO:0042330 taxis 5.52E-09 37 28 1.12E-08 50 42 7 16.66666667 41 GO:0010648 negative regulation of cell communication 2.27E-04 23 17 4.66E-08 36 30 5 16.66666667 41 GO:0023057 negative regulation of signaling 5.25E-04 22 17 4.66E-08 36 30 5 16.66666667 41 GO:0045664 regulation of neuron differentiation 5.01E-06 18 11 1.95E-06 19 18 3 16.66666667 41 GO:0009582 detection of abiotic stimulus 2.00E-04 7 4 7.02E-04 9 6 1 16.66666667 41 GO:0009581 detection of external stimulus 2.00E-04 7 4 7.02E-04 9 6 1 16.66666667 41 GO:0004872 receptor activity 4.02E-06 47 31 1.61E-03 118 78 13 16.66666667 31 GO:0065007 biological regulation 9.04E-11 328 228 1.41E-27 696 451 75 16.62971175 37 GO:0043169 cation binding 1.40E-08 122 94 1.12E-11 554 355 59 16.61971831 14 GO:0050789 regulation of biological process 7.59E-10 236 168 1.57E-28 303 223 37 16.59192825 37 GO:0044699 single-organism process 9.44E-07 550 373 1.28E-18 2075 1281 212 16.54957065 37 GO:0071944 cell periphery 3.40E-09 106 60 2.41E-30 311 212 35 16.50943396 31 GO:0050794 regulation of cellular process 1.55E-22 259 176 9.09E-35 527 358 59 16.48044693 37 GO:0050896 response to stimulus 5.81E-13 249 171 5.27E-24 759 522 86 16.47509579 31 GO:0048523 negative regulation of cellular process 1.99E-06 76 51 1.05E-10 111 73 12 16.43835616 41 GO:0044464 cell part 7.29E-04 373 265 1.78E-24 760 511 84 16.43835616 41 GO:0097458 neuron part 2.88E-05 39 29 1.32E-17 90 73 12 16.43835616 31 GO:0044699 single-organism process 1.08E-08 443 301 2.10E-10 1055 670 110 16.41791045 41 GO:0044459 plasma membrane part 5.56E-06 51 35 9.74E-18 93 67 11 16.41791045 41 GO:0005623 cell 7.54E-04 374 266 4.26E-24 761 512 84 16.40625 41 GO:0043005 neuron projection 4.91E-05 33 25 2.87E-14 72 61 10 16.39344262 31 GO:0050793 regulation of developmental process 2.73E-05 80 57 3.51E-14 171 116 19 16.37931034 37 GO:0051239 regulation of multicellular organismal process 1.58E-04 98 62 9.97E-17 320 214 35 16.35514019 31 GO:0048513 organ development 4.58E-08 133 82 1.90E-07 211 153 25 16.33986928 37 GO:0044449 contractile fiber part 9.13E-05 20 12 2.40E-12 74 49 8 16.32653061 37 GO:0009987 cellular process 2.31E-05 510 340 2.02E-36 1849 1172 191 16.29692833 4 GO:0003677 DNA binding 8.15E-07 42 31 3.60E-08 128 86 14 16.27906977 37 GO:0045944 positive regulation of transcription from RNA polymerase II promoter 1.05E-04 30 20 1.49E-10 62 43 7 16.27906977 41 GO:0010604 positive regulation of macromolecule metabolic process 7.47E-06 54 34 5.72E-09 60 43 7 16.27906977 37 GO:0006357 regulation of transcription from RNA polymerase II promoter 2.59E-07 53 34 4.50E-15 117 80 13 16.25 18 GO:0048519 negative regulation of biological process 4.95E-05 115 73 4.52E-08 107 74 12 16.21621622 41 GO:0048667 cell morphogenesis involved in neuron differentiation 9.83E-08 34 24 2.03E-08 44 37 6 16.21621622 41 GO:0042221 response to chemical 1.29E-07 87 61 2.79E-07 153 105 17 16.19047619 14 GO:0010468 regulation of gene expression 3.17E-04 61 47 1.36E-06 93 68 11 16.17647059 11 GO:0045165 cell fate commitment 4.16E-07 21 16 1.17E-15 89 62 10 16.12903226 11 GO:0051172 negative regulation of nitrogen compound metabolic process 5.19E-05 17 14 2.86E-05 48 31 5 16.12903226 18 GO:0048812 neuron projection morphogenesis 1.03E-08 40 30 3.95E-10 36 31 5 16.12903226 14 GO:0065007 biological regulation 3.60E-10 244 172 2.56E-19 321 230 37 16.08695652 37 GO:0048468 cell development 2.68E-08 99 64 3.78E-06 289 199 32 16.08040201 41 GO:0043167 ion binding 9.26E-05 153 112 2.71E-11 470 287 46 16.02787456 41 GO:0040011 locomotion 9.15E-12 174 121 3.44E-14 332 231 37 16.01731602 14 GO:0009888 tissue development 1.57E-05 55 37 8.96E-09 34 25 4 16 18 GO:0043005 neuron projection 7.34E-05 37 28 1.48E-17 59 50 8 16 37 GO:0007423 sensory organ development 1.03E-03 23 13 3.06E-06 27 25 4 16 41 GO:0030017 sarcomere 2.40E-04 15 8 1.02E-11 35 25 4 16 41 GO:0042995 cell projection 2.10E-04 45 33 4.10E-08 92 75 12 16 41 GO:0007154 cell communication 6.41E-14 157 119 1.53E-22 341 238 38 15.96638655 41 GO:0009987 cellular process 6.01E-05 429 304 1.49E-24 991 639 102 15.96244131 18 GO:0005886 plasma membrane 8.34E-08 95 54 1.49E-11 97 69 11 15.94202899 31 GO:0048609 multicellular organismal reproductive process 1.22E-03 68 43 6.40E-07 172 113 18 15.92920354 31 GO:0032504 multicellular organism reproduction 1.60E-03 68 43 9.07E-07 172 113 18 15.92920354 4 GO:0048513 organ development 1.85E-05 70 48 4.95E-06 152 107 17 15.88785047 31 GO:0048731 system development 5.38E-09 159 101 1.76E-11 271 196 31 15.81632653 14 GO:0044449 contractile fiber part 3.03E-05 15 9 2.04E-10 29 19 3 15.78947368 31 GO:0009605 response to external stimulus 2.81E-10 56 40 3.89E-06 74 57 9 15.78947368 37 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding 1.92E-04 8 6 4.43E-08 25 19 3 15.78947368 31 GO:0048583 regulation of response to stimulus 2.04E-06 63 45 9.69E-16 117 89 14 15.73033708 31 GO:0005215 transporter activity 1.24E-03 65 45 1.41E-05 132 70 11 15.71428571 4 GO:0006355 "regulation of transcription, DNA-templated" 2.73E-09 50 37 1.91E-11 131 83 13 15.6626506 4 GO:1903506 regulation of nucleic acid-templated transcription 2.73E-09 50 37 1.91E-11 131 83 13 15.6626506 31 GO:0045595 regulation of cell differentiation 6.20E-06 33 20 2.56E-07 39 32 5 15.625 41 GO:0007268 synaptic transmission 5.23E-04 23 18 7.42E-08 38 32 5 15.625 41 GO:0023052 signaling 1.48E-13 154 117 8.58E-23 338 237 37 15.61181435 41 GO:0050896 response to stimulus 7.06E-12 212 150 9.09E-18 422 295 46 15.59322034 14 GO:0044763 single-organism cellular process 2.69E-06 219 154 6.50E-13 346 244 38 15.57377049 4 GO:0016477 cell migration 2.00E-07 29 23 2.63E-10 65 45 7 15.55555556 4 GO:0051674 localization of cell 4.17E-07 29 23 7.30E-10 65 45 7 15.55555556 4 GO:0048870 cell motility 3.88E-07 29 23 7.30E-10 65 45 7 15.55555556 18 GO:0030030 cell projection organization 8.79E-08 55 42 2.35E-10 57 45 7 15.55555556 18 GO:0009605 response to external stimulus 2.49E-09 64 49 7.43E-08 57 45 7 15.55555556 37 GO:0010648 negative regulation of cell communication 3.59E-06 30 21 1.08E-08 55 45 7 15.55555556 37 GO:0023057 negative regulation of signaling 9.03E-06 29 21 1.08E-08 55 45 7 15.55555556 31 GO:0009987 cellular process 8.95E-07 410 276 1.52E-23 961 618 96 15.53398058 31 GO:0016477 cell migration 6.50E-10 50 37 4.93E-10 81 58 9 15.51724138 31 GO:0051674 localization of cell 7.47E-10 51 37 1.62E-09 81 58 9 15.51724138 31 GO:0048870 cell motility 1.98E-09 50 37 1.62E-09 81 58 9 15.51724138 37 GO:0007165 signal transduction 6.87E-14 158 115 6.83E-28 555 387 60 15.50387597 41 GO:0035556 intracellular signal transduction 1.75E-03 50 33 2.12E-08 100 71 11 15.49295775 4 GO:2001141 regulation of RNA biosynthetic process 7.58E-09 50 37 1.33E-11 132 84 13 15.47619048 3 GO:0003677 DNA binding 1.45E-07 40 31 2.00E-07 152 97 15 15.46391753 18 GO:0016043 cellular component organization 1.30E-06 184 130 3.54E-06 180 123 19 15.44715447 3 GO:0043565 sequence-specific DNA binding 4.84E-09 27 20 1.08E-10 105 65 10 15.38461538 3 GO:0040017 positive regulation of locomotion 3.60E-04 14 11 1.67E-05 16 13 2 15.38461538 4 GO:0000122 negative regulation of transcription from RNA polymerase II promoter 1.61E-07 16 12 7.79E-07 22 13 2 15.38461538 4 GO:0006935 chemotaxis 2.21E-08 22 19 2.45E-05 31 26 4 15.38461538 4 GO:0042330 taxis 4.06E-08 23 19 3.48E-05 32 26 4 15.38461538 5 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding 3.78E-05 11 7 2.30E-07 16 13 2 15.38461538 14 GO:0050896 response to stimulus 1.82E-06 134 94 1.36E-13 196 143 22 15.38461538 14 GO:0030017 sarcomere 2.10E-04 12 7 6.01E-10 21 13 2 15.38461538 18 GO:0048523 negative regulation of cellular process 9.11E-05 86 52 9.97E-10 77 52 8 15.38461538 18 GO:0030017 sarcomere 1.66E-03 15 7 2.02E-08 23 13 2 15.38461538 31 GO:0007268 synaptic transmission 2.22E-05 25 16 1.08E-07 37 26 4 15.38461538 37 GO:0043292 contractile fiber 2.73E-04 20 12 4.31E-13 81 52 8 15.38461538 37 GO:0005261 cation channel activity 7.59E-04 21 13 8.03E-08 67 39 6 15.38461538 41 GO:0030016 myofibril 5.15E-04 15 8 1.03E-11 37 26 4 15.38461538 41 GO:0048812 neuron projection morphogenesis 2.95E-08 35 24 4.82E-09 46 39 6 15.38461538 41 GO:0004674 protein serine/threonine kinase activity 1.87E-03 26 18 5.84E-07 61 39 6 15.38461538 41 GO:0019904 protein domain specific binding 1.40E-03 16 11 3.17E-03 16 13 2 15.38461538 37 GO:0007186 G-protein coupled receptor signaling pathway 1.86E-05 29 26 5.94E-17 157 124 19 15.32258065 14 GO:0051239 regulation of multicellular organismal process 1.40E-05 65 50 7.41E-12 94 72 11 15.27777778 14 GO:0048468 cell development 6.05E-07 61 47 1.09E-09 93 72 11 15.27777778 41 GO:0007165 signal transduction 2.85E-11 131 96 2.01E-19 311 216 33 15.27777778 31 GO:0022857 transmembrane transporter activity 1.23E-03 58 39 1.14E-04 110 59 9 15.25423729 37 GO:0006468 protein phosphorylation 1.10E-03 54 38 2.39E-06 164 105 16 15.23809524 31 GO:0032879 regulation of localization 1.43E-05 40 32 2.39E-10 65 46 7 15.2173913 4 GO:0003676 nucleic acid binding 5.87E-06 62 49 2.51E-05 185 125 19 15.2 18 GO:0071840 cellular component organization or biogenesis 1.17E-05 186 132 1.55E-05 182 125 19 15.2 41 GO:0044700 single organism signaling 7.25E-14 153 116 7.79E-23 338 237 36 15.18987342 5 GO:0016021 integral component of membrane 3.14E-08 187 121 3.12E-03 263 178 27 15.16853933 3 GO:0045202 synapse 1.95E-05 19 15 8.98E-07 42 33 5 15.15151515 18 GO:0061564 axon development 1.56E-09 40 31 4.03E-10 45 33 5 15.15151515 31 GO:0048519 negative regulation of biological process 8.99E-06 96 60 2.44E-07 152 99 15 15.15151515 37 GO:0010604 positive regulation of macromolecule metabolic process 8.15E-04 54 33 1.44E-09 95 66 10 15.15151515 37 GO:0051716 cellular response to stimulus 8.01E-10 174 124 5.83E-23 599 416 63 15.14423077 31 GO:0044703 multi-organism reproductive process 7.85E-04 71 45 4.00E-07 180 119 18 15.12605042 4 GO:0006351 "transcription, DNA-templated" 3.79E-07 52 38 9.14E-11 134 86 13 15.11627907 4 GO:0097659 nucleic acid-templated transcription 3.79E-07 52 38 1.38E-10 134 86 13 15.11627907 41 GO:0071840 cellular component organization or biogenesis 8.67E-05 154 106 8.05E-08 298 199 30 15.07537688 14 GO:0050794 regulation of cellular process 2.23E-10 168 122 5.92E-25 253 186 28 15.05376344 3 GO:0006351 "transcription, DNA-templated" 1.60E-05 43 32 1.14E-10 161 100 15 15 3 GO:0097659 nucleic acid-templated transcription 1.60E-05 43 32 1.80E-10 161 100 15 15 5 GO:0031224 intrinsic component of membrane 1.52E-08 190 122 1.81E-03 266 180 27 15 14 GO:0043292 contractile fiber 7.54E-05 15 9 1.17E-10 31 20 3 15 31 GO:0006928 movement of cell or subcellular component 4.57E-10 64 47 5.35E-11 107 80 12 15 31 GO:0051172 negative regulation of nitrogen compound metabolic process 6.10E-08 33 21 4.81E-06 34 20 3 15 37 GO:0001012 RNA polymerase II regulatory region DNA binding 1.92E-04 8 6 2.47E-09 29 20 3 15 37 GO:0001654 eye development 3.63E-04 20 11 9.09E-05 20 20 3 15 37 GO:0007166 cell surface receptor signaling pathway 5.55E-09 82 61 1.82E-25 250 187 28 14.97326203 37 GO:0048523 negative regulation of cellular process 3.63E-07 95 58 3.78E-12 189 127 19 14.96062992 4 GO:0051252 regulation of RNA metabolic process 2.20E-08 51 38 4.16E-12 135 87 13 14.94252874 4 GO:0032774 RNA biosynthetic process 7.49E-07 52 38 1.56E-10 135 87 13 14.94252874 4 GO:0048731 system development 3.68E-06 84 60 4.14E-08 191 134 20 14.92537313 3 GO:0032774 RNA biosynthetic process 1.22E-05 44 32 1.30E-10 163 101 15 14.85148515 31 GO:0051239 regulation of multicellular organismal process 2.59E-05 83 58 8.26E-16 189 128 19 14.84375 37 GO:0032940 secretion by cell 7.51E-06 26 20 3.32E-05 72 54 8 14.81481481 41 GO:0043087 regulation of GTPase activity 1.23E-03 12 11 5.71E-07 36 27 4 14.81481481 31 GO:0042221 response to chemical 6.73E-10 89 62 2.16E-03 128 88 13 14.77272727 18 GO:0010171 body morphogenesis 9.02E-04 66 41 1.43E-08 95 61 9 14.75409836 37 GO:0010646 regulation of cell communication 1.67E-07 69 44 5.98E-17 162 122 18 14.75409836 37 GO:0023051 regulation of signaling 3.63E-07 68 44 2.12E-16 160 122 18 14.75409836 41 GO:0005886 plasma membrane 5.99E-07 80 55 7.20E-27 179 122 18 14.75409836 41 GO:0007186 G-protein coupled receptor signaling pathway 1.33E-04 24 19 1.61E-08 82 61 9 14.75409836 3 GO:0033057 multicellular organismal reproductive behavior 1.66E-06 27 20 1.52E-13 103 68 10 14.70588235 37 GO:0016310 phosphorylation 1.41E-03 76 53 2.41E-05 211 136 20 14.70588235 41 GO:0048585 negative regulation of response to stimulus 4.25E-04 24 15 3.21E-08 40 34 5 14.70588235 37 GO:0010605 negative regulation of macromolecule metabolic process 1.16E-03 45 30 2.51E-03 122 75 11 14.66666667 41 GO:0051179 localization 3.65E-05 173 131 2.18E-07 479 300 44 14.66666667 37 GO:0044763 single-organism cellular process 4.64E-09 386 262 3.18E-37 1512 969 142 14.65428277 41 GO:0016043 cellular component organization 2.63E-05 151 104 1.45E-08 293 198 29 14.64646465 41 GO:0061564 axon development 1.51E-09 36 26 4.87E-07 54 41 6 14.63414634 4 GO:0019219 regulation of nucleobase-containing compound metabolic process 1.03E-07 52 39 8.90E-12 138 89 13 14.60674157 4 GO:2000112 regulation of cellular macromolecule biosynthetic process 6.00E-08 51 38 1.95E-11 140 89 13 14.60674157 41 GO:0044763 single-organism cellular process 4.51E-08 325 233 8.40E-24 812 521 76 14.58733205 3 GO:0006366 transcription from RNA polymerase II promoter 5.23E-04 23 16 2.59E-11 70 48 7 14.58333333 14 GO:0010171 body morphogenesis 5.72E-04 42 26 1.60E-06 66 48 7 14.58333333 14 GO:0005515 protein binding 1.67E-04 132 93 5.54E-10 153 117 17 14.52991453 3 GO:0019098 reproductive behavior 2.52E-06 27 20 8.95E-14 104 69 10 14.49275362 3 GO:0044705 multi-organism reproductive behavior 2.24E-06 27 20 8.95E-14 104 69 10 14.49275362 3 GO:0044706 multi-multicellular organism process 4.21E-06 27 20 1.02E-13 104 69 10 14.49275362 3 GO:0051705 multi-organism behavior 3.66E-07 29 20 1.33E-13 104 69 10 14.49275362 31 GO:0048522 positive regulation of cellular process 5.06E-07 86 53 4.16E-10 107 69 10 14.49275362 37 GO:0004674 protein serine/threonine kinase activity 1.40E-03 30 22 1.60E-08 103 69 10 14.49275362 4 GO:0051171 regulation of nitrogen compound metabolic process 2.55E-07 52 39 3.48E-12 140 90 13 14.44444444 4 GO:0010556 regulation of macromolecule biosynthetic process 1.71E-07 51 38 1.69E-11 141 90 13 14.44444444 4 GO:0034654 nucleobase-containing compound biosynthetic process 1.04E-05 55 40 8.75E-09 144 90 13 14.44444444 3 GO:0006355 "regulation of transcription, DNA-templated" 1.18E-06 40 31 1.19E-11 158 97 14 14.43298969 3 GO:1903506 regulation of nucleic acid-templated transcription 1.18E-06 40 31 1.19E-11 158 97 14 14.43298969 41 GO:0048519 negative regulation of biological process 2.94E-04 95 65 7.72E-11 170 118 17 14.40677966 37 GO:0048583 regulation of response to stimulus 6.04E-08 81 54 3.37E-17 191 139 20 14.38848921 3 GO:0003676 nucleic acid binding 1.18E-06 58 45 8.65E-07 238 153 22 14.37908497 41 GO:0051716 cellular response to stimulus 6.30E-08 144 105 1.62E-15 330 230 33 14.34782609 3 GO:2001141 regulation of RNA biosynthetic process 2.52E-06 40 31 9.30E-12 159 98 14 14.28571429 3 GO:0007409 axonogenesis 1.83E-04 14 10 5.07E-11 44 35 5 14.28571429 3 GO:0043269 regulation of ion transport 6.62E-05 8 5 5.92E-06 20 14 2 14.28571429 4 GO:0007610 behavior 9.59E-07 41 33 4.45E-14 111 84 12 14.28571429 4 GO:0031326 regulation of cellular biosynthetic process 2.94E-07 51 38 5.84E-12 143 91 13 14.28571429 4 GO:0009889 regulation of biosynthetic process 3.51E-07 51 38 8.94E-12 143 91 13 14.28571429 4 GO:0000976 transcription regulatory region sequence-specific DNA binding 7.37E-07 11 9 2.20E-07 19 14 2 14.28571429 4 GO:0016070 RNA metabolic process 3.33E-04 58 43 3.61E-06 151 98 14 14.28571429 4 GO:0009891 positive regulation of biosynthetic process 2.53E-05 24 18 9.19E-05 29 21 3 14.28571429 4 GO:0031328 positive regulation of cellular biosynthetic process 2.24E-05 24 18 9.19E-05 29 21 3 14.28571429 4 GO:0010557 positive regulation of macromolecule biosynthetic process 1.04E-05 24 18 1.23E-04 28 21 3 14.28571429 14 GO:0007154 cell communication 9.56E-09 102 77 2.25E-14 156 112 16 14.28571429 14 GO:0030016 myofibril 1.00E-04 13 8 6.25E-10 22 14 2 14.28571429 14 GO:0048729 tissue morphogenesis 1.81E-05 43 29 3.53E-06 19 14 2 14.28571429 14 GO:0001071 nucleic acid binding transcription factor activity 1.21E-06 29 22 2.14E-04 48 35 5 14.28571429 14 GO:0003700 sequence-specific DNA binding transcription factor activity 3.41E-06 28 21 2.14E-04 48 35 5 14.28571429 18 GO:0030016 myofibril 1.21E-03 16 8 1.25E-09 26 14 2 14.28571429 18 GO:0051270 regulation of cellular component movement 1.36E-06 21 18 1.32E-04 15 14 2 14.28571429 18 GO:0001012 RNA polymerase II regulatory region DNA binding 1.30E-03 7 5 9.28E-04 10 7 1 14.28571429 27 GO:0006357 regulation of transcription from RNA polymerase II promoter 1.32E-04 13 11 1.93E-04 8 7 1 14.28571429 31 GO:0010557 positive regulation of macromolecule biosynthetic process 4.52E-08 43 30 4.22E-09 46 28 4 14.28571429 31 GO:0009891 positive regulation of biosynthetic process 2.77E-08 45 31 4.46E-09 47 28 4 14.28571429 31 GO:0031328 positive regulation of cellular biosynthetic process 6.27E-08 44 31 4.46E-09 47 28 4 14.28571429 31 GO:0051960 regulation of nervous system development 3.57E-07 23 14 9.82E-08 24 21 3 14.28571429 31 GO:0008078 mesodermal cell migration 1.29E-03 5 4 3.17E-07 9 7 1 14.28571429 31 GO:0015075 ion transmembrane transporter activity 6.76E-04 49 31 3.62E-04 84 49 7 14.28571429 37 GO:0046903 secretion 1.06E-05 28 21 1.92E-05 75 56 8 14.28571429 41 GO:0030182 neuron differentiation 7.43E-11 58 38 6.18E-09 77 63 9 14.28571429 41 GO:0048666 neuron development 9.68E-09 46 31 1.99E-08 69 56 8 14.28571429 41 GO:0048858 cell projection morphogenesis 2.59E-06 35 24 1.66E-07 50 42 6 14.28571429 41 GO:0032990 cell part morphogenesis 4.58E-06 35 24 4.13E-07 50 42 6 14.28571429 41 GO:0010721 negative regulation of cell development 1.63E-03 8 5 2.43E-03 8 7 1 14.28571429 41 GO:0071944 cell periphery 2.69E-07 87 60 1.04E-28 198 134 19 14.17910448 11 GO:0001071 nucleic acid binding transcription factor activity 4.90E-12 31 25 1.24E-09 180 120 17 14.16666667 11 GO:0003700 sequence-specific DNA binding transcription factor activity 4.33E-12 31 25 1.24E-09 180 120 17 14.16666667 4 GO:0019438 aromatic compound biosynthetic process 2.60E-05 55 40 1.58E-08 146 92 13 14.13043478 4 GO:0018130 heterocycle biosynthetic process 3.14E-05 55 40 3.32E-08 146 92 13 14.13043478 41 GO:0009605 response to external stimulus 8.42E-12 62 42 6.90E-11 90 71 10 14.08450704 3 GO:0018991 oviposition 5.61E-07 26 19 5.62E-13 96 64 9 14.0625 41 GO:0030030 cell projection organization 2.87E-09 52 36 2.45E-07 71 57 8 14.03508772 37 GO:0043167 ion binding 1.20E-07 194 132 2.50E-14 857 542 76 14.02214022 3 GO:0007610 behavior 2.16E-09 43 31 4.27E-18 142 100 14 14 14 GO:0060089 molecular transducer activity 1.04E-05 39 29 3.76E-05 69 50 7 14 18 GO:0032989 cellular component morphogenesis 6.34E-08 62 42 3.25E-09 71 50 7 14 41 GO:0031175 neuron projection development 7.22E-09 41 28 9.91E-08 63 50 7 14 4 GO:1901362 organic cyclic compound biosynthetic process 7.50E-05 55 40 7.24E-08 147 93 13 13.97849462 37 GO:0009892 negative regulation of metabolic process 1.42E-03 48 31 1.95E-03 128 79 11 13.92405063 37 GO:0038023 signaling receptor activity 7.43E-08 41 30 2.56E-05 213 144 20 13.88888889 4 GO:0044271 cellular nitrogen compound biosynthetic process 4.67E-05 55 40 9.78E-09 149 94 13 13.82978723 18 GO:0042995 cell projection 1.09E-03 49 37 5.21E-10 69 58 8 13.79310345 18 GO:0032879 regulation of localization 1.99E-09 58 43 2.32E-05 37 29 4 13.79310345 37 GO:1901700 response to oxygen-containing compound 1.40E-03 26 12 3.11E-03 36 29 4 13.79310345 3 GO:0051252 regulation of RNA metabolic process 1.16E-05 40 31 2.04E-12 163 102 14 13.7254902 4 GO:0048522 positive regulation of cellular process 9.09E-04 42 31 1.20E-05 70 51 7 13.7254902 41 GO:0000902 cell morphogenesis 6.39E-05 40 27 1.26E-08 60 51 7 13.7254902 41 GO:0004871 signal transducer activity 6.29E-06 41 29 7.30E-06 140 95 13 13.68421053 14 GO:0051716 cellular response to stimulus 9.06E-05 92 65 6.30E-13 158 117 16 13.67521368 3 GO:0034654 nucleobase-containing compound biosynthetic process 3.72E-06 51 34 4.73E-09 176 110 15 13.63636364 18 GO:0048585 negative regulation of response to stimulus 5.63E-07 34 24 3.52E-06 26 22 3 13.63636364 31 GO:0030016 myofibril 7.58E-04 14 9 9.81E-11 35 22 3 13.63636364 31 GO:0048729 tissue morphogenesis 5.86E-08 62 40 1.12E-04 28 22 3 13.63636364 4 GO:0009653 anatomical structure morphogenesis 1.39E-07 82 63 1.10E-12 186 118 16 13.55932203 4 GO:0010468 regulation of gene expression 9.77E-07 54 40 1.15E-08 149 96 13 13.54166667 5 GO:0034220 ion transmembrane transport 1.98E-03 37 21 3.08E-03 58 37 5 13.51351351 14 GO:0007165 signal transduction 5.15E-06 81 59 1.38E-15 151 111 15 13.51351351 31 GO:0031324 negative regulation of cellular metabolic process 1.57E-05 39 26 2.07E-06 58 37 5 13.51351351 37 GO:0048519 negative regulation of biological process 2.18E-05 116 69 1.64E-10 283 185 25 13.51351351 41 GO:0010646 regulation of cell communication 2.27E-04 51 35 1.48E-13 98 74 10 13.51351351 3 GO:0009893 positive regulation of metabolic process 1.70E-05 32 21 4.02E-09 76 52 7 13.46153846 37 GO:0016020 membrane 1.66E-05 231 150 2.21E-09 860 565 76 13.45132743 37 GO:0004871 signal transducer activity 1.01E-07 51 39 1.69E-08 257 179 24 13.40782123 3 GO:0019438 aromatic compound biosynthetic process 1.86E-06 53 36 1.22E-08 178 112 15 13.39285714 3 GO:0018130 heterocycle biosynthetic process 2.28E-06 53 36 2.85E-08 178 112 15 13.39285714 14 GO:0044700 single organism signaling 2.76E-08 98 73 5.79E-15 156 112 15 13.39285714 14 GO:0023052 signaling 1.63E-08 100 75 6.07E-15 156 112 15 13.39285714 3 GO:2000112 regulation of cellular macromolecule biosynthetic process 1.74E-06 43 33 1.93E-12 172 105 14 13.33333333 3 GO:0019219 regulation of nucleobase-containing compound metabolic process 6.67E-05 40 31 4.08E-12 167 105 14 13.33333333 4 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity 8.68E-08 14 11 5.65E-09 23 15 2 13.33333333 5 GO:0001012 RNA polymerase II regulatory region DNA binding 3.78E-05 11 7 8.49E-09 19 15 2 13.33333333 5 GO:0004930 G-protein coupled receptor activity 3.47E-05 24 21 1.71E-06 51 45 6 13.33333333 5 GO:0019904 protein domain specific binding 2.08E-05 30 20 3.11E-05 18 15 2 13.33333333 31 GO:0045664 regulation of neuron differentiation 7.59E-06 17 11 2.44E-05 17 15 2 13.33333333 41 GO:0023051 regulation of signaling 4.20E-04 50 35 1.07E-13 98 75 10 13.33333333 41 GO:0009966 regulation of signal transduction 3.82E-04 44 30 2.97E-10 81 60 8 13.33333333 41 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity 3.81E-05 16 10 7.82E-08 26 15 2 13.33333333 3 GO:0044271 cellular nitrogen compound biosynthetic process 3.49E-06 53 36 1.04E-08 181 113 15 13.27433628 3 GO:1901362 organic cyclic compound biosynthetic process 5.82E-06 53 36 7.85E-08 179 113 15 13.27433628 18 GO:0051179 localization 1.50E-10 230 168 8.00E-04 280 189 25 13.22751323 11 GO:0006355 "regulation of transcription, DNA-templated" 1.58E-06 42 36 1.70E-10 264 174 23 13.2183908 11 GO:1903506 regulation of nucleic acid-templated transcription 1.58E-06 42 36 1.70E-10 264 174 23 13.2183908 3 GO:0010556 regulation of macromolecule biosynthetic process 6.71E-07 45 34 1.92E-12 173 106 14 13.20754717 4 GO:0051094 positive regulation of developmental process 1.37E-04 28 22 2.93E-07 75 53 7 13.20754717 41 GO:0007166 cell surface receptor signaling pathway 1.95E-06 65 50 2.09E-15 139 106 14 13.20754717 11 GO:2000112 regulation of cellular macromolecule biosynthetic process 4.71E-07 47 39 5.78E-09 277 182 24 13.18681319 3 GO:0061564 axon development 1.11E-04 15 11 4.69E-08 52 38 5 13.15789474 31 GO:0006935 chemotaxis 2.65E-07 30 24 9.54E-08 45 38 5 13.15789474 11 GO:2001141 regulation of RNA biosynthetic process 3.45E-06 42 36 1.10E-10 266 175 23 13.14285714 4 GO:0006928 movement of cell or subcellular component 3.15E-08 38 29 1.63E-10 83 61 8 13.1147541 11 GO:0010556 regulation of macromolecule biosynthetic process 1.21E-06 47 39 5.28E-09 279 183 24 13.1147541 31 GO:0044763 single-organism cellular process 5.07E-11 317 217 7.00E-19 770 504 66 13.0952381 31 GO:0016043 cellular component organization 3.33E-05 141 91 1.29E-08 286 191 25 13.08900524 3 GO:0051171 regulation of nitrogen compound metabolic process 5.81E-05 41 31 9.74E-13 170 107 14 13.08411215 4 GO:0007411 axon guidance 5.82E-07 16 13 3.70E-07 28 23 3 13.04347826 4 GO:0097485 neuron projection guidance 6.65E-07 16 13 4.37E-07 28 23 3 13.04347826 4 GO:0007409 axonogenesis 1.72E-05 17 14 7.04E-07 31 23 3 13.04347826 4 GO:0010628 positive regulation of gene expression 4.02E-06 25 18 1.12E-04 29 23 3 13.04347826 21 GO:0048513 organ development 2.04E-05 42 32 9.12E-05 90 69 9 13.04347826 11 GO:0031326 regulation of cellular biosynthetic process 8.18E-07 48 40 2.27E-09 282 185 24 12.97297297 11 GO:0009889 regulation of biosynthetic process 9.66E-07 48 40 4.16E-09 282 185 24 12.97297297 3 GO:0031326 regulation of cellular biosynthetic process 2.67E-06 44 33 3.87E-13 176 108 14 12.96296296 3 GO:0009889 regulation of biosynthetic process 1.28E-06 45 34 6.46E-13 176 108 14 12.96296296 31 GO:0010628 positive regulation of gene expression 1.80E-07 42 28 2.14E-09 48 31 4 12.90322581 37 GO:0051179 localization 2.06E-04 197 136 6.40E-09 882 536 69 12.87313433 11 GO:0051252 regulation of RNA metabolic process 1.63E-05 42 36 4.44E-11 271 179 23 12.84916201 11 GO:0006351 "transcription, DNA-templated" 1.21E-05 46 37 1.79E-09 271 179 23 12.84916201 11 GO:0097659 nucleic acid-templated transcription 1.21E-05 46 37 3.36E-09 271 179 23 12.84916201 4 GO:0040012 regulation of locomotion 4.31E-06 25 23 4.05E-11 43 39 5 12.82051282 31 GO:0071840 cellular component organization or biogenesis 1.42E-04 143 93 4.44E-08 292 195 25 12.82051282 31 GO:0042330 taxis 3.53E-07 32 24 9.45E-08 47 39 5 12.82051282 11 GO:0032774 RNA biosynthetic process 9.71E-06 47 37 2.93E-09 274 180 23 12.77777778 31 GO:0023052 signaling 2.96E-16 153 108 6.64E-24 334 235 30 12.76595745 11 GO:0003677 DNA binding 6.59E-08 43 33 2.69E-06 261 165 21 12.72727273 31 GO:0007154 cell communication 2.54E-16 155 109 5.56E-24 338 237 30 12.65822785 11 GO:0019219 regulation of nucleobase-containing compound metabolic process 2.11E-05 44 38 5.72E-10 275 183 23 12.56830601 3 GO:0007186 G-protein coupled receptor signaling pathway 1.09E-04 14 14 1.46E-08 75 56 7 12.5 4 GO:0031323 regulation of cellular metabolic process 5.19E-06 61 45 1.33E-10 167 104 13 12.5 4 GO:0051240 positive regulation of multicellular organismal process 1.79E-04 28 21 1.08E-06 78 56 7 12.5 4 GO:1902679 negative regulation of RNA biosynthetic process 5.35E-07 19 15 1.26E-06 25 16 2 12.5 4 GO:1903507 negative regulation of nucleic acid-templated transcription 4.79E-07 19 15 1.26E-06 25 16 2 12.5 4 GO:0045892 "negative regulation of transcription, DNA-templated" 4.79E-07 19 15 1.26E-06 25 16 2 12.5 4 GO:0051253 negative regulation of RNA metabolic process 1.02E-06 19 15 2.47E-06 25 16 2 12.5 11 GO:0001709 cell fate determination 8.14E-07 10 6 2.68E-08 26 16 2 12.5 11 GO:0019438 aromatic compound biosynthetic process 1.09E-05 54 41 1.50E-07 307 200 25 12.5 18 GO:0001667 ameboidal-type cell migration 6.41E-07 21 18 7.42E-06 12 8 1 12.5 18 GO:0048569 post-embryonic organ development 9.43E-04 38 27 1.11E-05 49 40 5 12.5 18 GO:0031226 intrinsic component of plasma membrane 3.70E-04 22 14 2.00E-04 21 16 2 12.5 31 GO:0008104 protein localization 1.81E-03 47 34 1.15E-03 79 56 7 12.5 37 GO:0008092 cytoskeletal protein binding 1.05E-03 26 17 1.16E-14 77 56 7 12.5 37 GO:0001709 cell fate determination 9.03E-04 11 5 4.02E-08 27 16 2 12.5 37 GO:0048592 eye morphogenesis 1.54E-03 15 8 5.09E-06 16 16 2 12.5 37 GO:0090596 sensory organ morphogenesis 3.24E-04 18 9 2.08E-05 16 16 2 12.5 41 GO:0048468 cell development 4.85E-08 86 58 8.99E-06 164 112 14 12.5 41 GO:0051606 detection of stimulus 4.04E-05 10 7 7.62E-04 12 8 1 12.5 41 GO:0032940 secretion by cell 3.48E-06 24 18 3.03E-03 38 32 4 12.5 11 GO:0051171 regulation of nitrogen compound metabolic process 4.21E-05 44 38 2.90E-10 278 185 23 12.43243243 3 GO:0048518 positive regulation of biological process 1.04E-05 93 68 8.65E-19 205 137 17 12.40875912 31 GO:0044700 single organism signaling 3.42E-16 151 106 6.03E-24 334 235 29 12.34042553 22 GO:0043565 sequence-specific DNA binding 1.80E-07 16 13 3.53E-12 115 73 9 12.32876712 11 GO:1901362 organic cyclic compound biosynthetic process 3.22E-05 54 41 1.20E-06 310 203 25 12.31527094 41 GO:0044425 membrane part 7.96E-04 121 80 6.35E-06 368 252 31 12.3015873 4 GO:0030154 cell differentiation 4.38E-06 58 42 3.01E-07 150 106 13 12.26415094 37 GO:0098662 inorganic cation transmembrane transport 1.87E-03 20 11 3.13E-07 87 49 6 12.24489796 37 GO:0098655 cation transmembrane transport 2.09E-03 20 11 3.13E-07 87 49 6 12.24489796 31 GO:0007165 signal transduction 1.99E-13 130 92 3.81E-19 303 213 26 12.20657277 3 GO:0060089 molecular transducer activity 2.10E-04 25 22 3.85E-05 127 82 10 12.19512195 4 GO:0048666 neuron development 6.68E-07 26 20 3.77E-08 53 41 5 12.19512195 4 GO:0048569 post-embryonic organ development 1.83E-04 21 15 4.35E-05 52 41 5 12.19512195 37 GO:0009968 negative regulation of signal transduction 5.67E-05 25 17 5.30E-08 51 41 5 12.19512195 4 GO:0080090 regulation of primary metabolic process 3.25E-06 60 45 3.00E-12 168 107 13 12.14953271 11 GO:0034654 nucleobase-containing compound biosynthetic process 4.01E-05 51 39 4.60E-08 303 198 24 12.12121212 37 GO:0004930 G-protein coupled receptor activity 2.48E-05 18 16 5.73E-12 111 91 11 12.08791209 31 GO:0009966 regulation of signal transduction 1.40E-04 43 29 5.66E-09 76 58 7 12.06896552 4 GO:0009605 response to external stimulus 1.08E-09 36 28 8.19E-09 65 50 6 12 4 GO:0048667 cell morphogenesis involved in neuron differentiation 9.39E-05 17 14 2.65E-07 33 25 3 12 4 GO:0048812 neuron projection morphogenesis 9.39E-05 17 14 4.74E-07 33 25 3 12 31 GO:0030154 cell differentiation 2.02E-08 107 69 3.26E-10 213 150 18 12 31 GO:0060284 regulation of cell development 6.40E-06 21 13 1.92E-09 28 25 3 12 4 GO:0019222 regulation of metabolic process 3.76E-06 70 53 1.17E-13 213 142 17 11.97183099 31 GO:0050896 response to stimulus 3.28E-11 197 134 1.33E-16 407 285 34 11.92982456 4 GO:0006366 transcription from RNA polymerase II promoter 7.39E-07 32 24 8.38E-12 61 42 5 11.9047619 21 GO:0048731 system development 5.27E-05 47 35 5.74E-06 112 84 10 11.9047619 11 GO:0018130 heterocycle biosynthetic process 2.73E-05 53 40 2.24E-07 309 202 24 11.88118812 4 GO:0048869 cellular developmental process 1.72E-05 59 43 3.81E-07 155 110 13 11.81818182 3 GO:0010468 regulation of gene expression 1.21E-05 46 34 8.04E-12 194 119 14 11.76470588 4 GO:0044212 transcription regulatory region DNA binding 1.51E-07 15 12 1.82E-09 25 17 2 11.76470588 4 GO:0000975 regulatory region DNA binding 2.10E-07 15 12 2.39E-09 25 17 2 11.76470588 4 GO:0001067 regulatory region nucleic acid binding 2.10E-07 15 12 2.39E-09 25 17 2 11.76470588 4 GO:0045934 negative regulation of nucleobase-containing compound metabolic process 4.79E-06 19 15 4.27E-06 27 17 2 11.76470588 11 GO:0010468 regulation of gene expression 4.92E-05 47 39 4.18E-08 316 204 24 11.76470588 11 GO:0044271 cellular nitrogen compound biosynthetic process 4.03E-05 53 40 1.04E-07 313 204 24 11.76470588 14 GO:0060429 epithelium development 3.45E-05 47 31 7.38E-09 26 17 2 11.76470588 18 GO:0009968 negative regulation of signal transduction 2.41E-06 28 19 9.24E-05 20 17 2 11.76470588 31 GO:0006357 regulation of transcription from RNA polymerase II promoter 3.50E-10 51 33 2.42E-16 79 51 6 11.76470588 31 GO:0030029 actin filament-based process 8.53E-07 31 19 1.76E-04 56 34 4 11.76470588 4 GO:0060255 regulation of macromolecule metabolic process 7.58E-06 62 47 1.47E-09 174 111 13 11.71171171 3 GO:0048583 regulation of response to stimulus 5.31E-05 32 19 4.69E-19 117 86 10 11.62790698 4 GO:0040011 locomotion 7.86E-09 90 66 1.65E-14 247 172 20 11.62790698 4 GO:0050794 regulation of cellular process 1.66E-10 127 99 1.04E-29 390 267 31 11.61048689 41 GO:0032989 cellular component morphogenesis 1.71E-05 48 31 3.05E-07 95 69 8 11.5942029 31 GO:0048869 cellular developmental process 2.04E-07 109 70 9.87E-11 223 156 18 11.53846154 37 GO:0003779 actin binding 1.14E-03 15 9 9.62E-09 43 26 3 11.53846154 31 GO:0051716 cellular response to stimulus 2.10E-09 141 98 1.83E-15 322 226 26 11.50442478 4 GO:0046872 metal ion binding 5.68E-05 50 44 3.54E-07 213 140 16 11.42857143 21 GO:0043565 sequence-specific DNA binding 1.51E-06 17 14 3.88E-05 46 35 4 11.42857143 31 GO:0031325 positive regulation of cellular metabolic process 7.51E-06 53 36 7.72E-07 60 35 4 11.42857143 41 GO:0044449 contractile fiber part 8.58E-04 16 9 2.07E-11 49 35 4 11.42857143 4 GO:0050789 regulation of biological process 6.41E-08 168 126 1.80E-34 471 324 37 11.41975309 3 GO:0045165 cell fate commitment 2.00E-06 19 14 1.45E-15 60 44 5 11.36363636 3 GO:0009888 tissue development 2.46E-05 38 26 5.52E-12 61 44 5 11.36363636 31 GO:0006366 transcription from RNA polymerase II promoter 6.70E-08 53 33 3.20E-14 81 53 6 11.32075472 3 GO:0031323 regulation of cellular metabolic process 2.52E-06 56 39 1.38E-13 214 133 15 11.27819549 4 GO:0048583 regulation of response to stimulus 1.13E-05 37 31 1.07E-13 89 71 8 11.26760563 4 GO:0043169 cation binding 1.05E-04 50 44 1.39E-07 216 142 16 11.26760563 4 GO:0050793 regulation of developmental process 6.33E-07 52 38 2.50E-12 128 89 10 11.23595506 3 GO:0080090 regulation of primary metabolic process 8.45E-06 53 38 8.60E-15 212 134 15 11.19402985 3 GO:1901363 heterocyclic compound binding 6.67E-05 89 63 1.05E-09 413 260 29 11.15384615 3 GO:0006357 regulation of transcription from RNA polymerase II promoter 1.97E-04 21 15 1.98E-12 67 45 5 11.11111111 3 GO:0048666 neuron development 2.47E-04 19 14 2.23E-10 68 54 6 11.11111111 3 GO:0042995 cell projection 4.11E-04 23 18 1.47E-07 82 72 8 11.11111111 3 GO:0010557 positive regulation of macromolecule biosynthetic process 1.10E-04 20 13 1.73E-07 40 27 3 11.11111111 3 GO:0022843 voltage-gated cation channel activity 4.31E-04 6 5 9.07E-07 16 9 1 11.11111111 3 GO:0005244 voltage-gated ion channel activity 1.83E-04 7 5 4.88E-06 17 9 1 11.11111111 3 GO:0022832 voltage-gated channel activity 1.83E-04 7 5 4.88E-06 17 9 1 11.11111111 4 GO:0000904 cell morphogenesis involved in differentiation 3.03E-05 20 15 5.68E-08 36 27 3 11.11111111 4 GO:0031175 neuron projection development 1.22E-05 21 16 2.48E-07 48 36 4 11.11111111 4 GO:0032879 regulation of localization 4.25E-04 22 17 4.77E-07 45 36 4 11.11111111 4 GO:0051172 negative regulation of nitrogen compound metabolic process 8.11E-06 19 15 2.44E-06 28 18 2 11.11111111 4 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding 5.18E-04 5 5 6.70E-06 13 9 1 11.11111111 4 GO:0061564 axon development 1.18E-05 18 14 8.46E-06 39 27 3 11.11111111 4 GO:0048468 cell development 3.69E-07 48 34 2.46E-04 113 81 9 11.11111111 4 GO:0010604 positive regulation of macromolecule metabolic process 2.52E-04 28 20 3.91E-04 35 27 3 11.11111111 4 GO:0060322 head development 2.03E-04 13 9 4.52E-04 11 9 1 11.11111111 18 GO:0035295 tube development 1.69E-07 40 26 1.20E-03 24 18 2 11.11111111 21 GO:0009653 anatomical structure morphogenesis 1.60E-07 50 37 7.77E-08 106 72 8 11.11111111 27 GO:0006928 movement of cell or subcellular component 1.21E-04 16 12 4.34E-05 12 9 1 11.11111111 31 GO:1902680 positive regulation of RNA biosynthetic process 9.38E-07 38 27 6.30E-09 43 27 3 11.11111111 31 GO:1903508 positive regulation of nucleic acid-templated transcription 1.33E-07 38 27 1.09E-08 42 27 3 11.11111111 31 GO:0045893 "positive regulation of transcription, DNA-templated" 1.33E-07 38 27 1.09E-08 42 27 3 11.11111111 31 GO:0010604 positive regulation of macromolecule metabolic process 7.34E-07 54 34 1.30E-08 58 36 4 11.11111111 31 GO:0048592 eye morphogenesis 3.72E-04 14 6 7.97E-04 9 9 1 11.11111111 31 GO:0090596 sensory organ morphogenesis 1.61E-04 16 6 1.50E-03 9 9 1 11.11111111 37 GO:0009966 regulation of signal transduction 1.81E-05 55 34 5.59E-12 133 99 11 11.11111111 31 GO:0016020 membrane 3.53E-04 177 120 6.44E-06 442 281 31 11.03202847 3 GO:0097159 organic cyclic compound binding 7.63E-05 89 63 5.25E-10 416 263 29 11.02661597 37 GO:0004888 transmembrane signaling receptor activity 3.58E-06 31 22 6.81E-10 158 118 13 11.01694915 3 GO:0050794 regulation of cellular process 3.77E-13 121 88 2.50E-38 498 329 36 10.94224924 3 GO:0019222 regulation of metabolic process 1.78E-07 67 48 1.17E-17 273 174 19 10.91954023 3 GO:0009653 anatomical structure morphogenesis 2.73E-06 70 48 2.70E-19 248 165 18 10.90909091 3 GO:0042221 response to chemical 2.63E-05 40 29 9.36E-08 140 92 10 10.86956522 4 GO:0043005 neuron projection 4.88E-04 18 13 3.41E-13 56 46 5 10.86956522 11 GO:0010171 body morphogenesis 4.89E-05 34 24 2.32E-08 216 129 14 10.85271318 11 GO:0009653 anatomical structure morphogenesis 2.39E-07 78 58 9.95E-22 430 286 31 10.83916084 4 GO:0007166 cell surface receptor signaling pathway 1.28E-05 36 29 3.86E-11 97 74 8 10.81081081 11 GO:0031323 regulation of cellular metabolic process 7.98E-06 58 44 6.80E-08 339 222 24 10.81081081 21 GO:0001071 nucleic acid binding transcription factor activity 1.80E-09 20 15 1.23E-06 53 37 4 10.81081081 21 GO:0003700 sequence-specific DNA binding transcription factor activity 1.66E-09 20 15 1.23E-06 53 37 4 10.81081081 31 GO:0045202 synapse 1.20E-03 27 21 1.11E-07 47 37 4 10.81081081 4 GO:0065007 biological regulation 1.04E-07 172 128 3.32E-29 527 343 37 10.78717201 31 GO:0060089 molecular transducer activity 1.89E-09 59 45 1.27E-07 150 102 11 10.78431373 3 GO:0009605 response to external stimulus 2.29E-08 31 21 1.05E-10 82 65 7 10.76923077 3 GO:0009891 positive regulation of biosynthetic process 7.91E-05 21 13 5.50E-08 42 28 3 10.71428571 3 GO:0031328 positive regulation of cellular biosynthetic process 7.11E-05 21 13 5.50E-08 42 28 3 10.71428571 3 GO:0010628 positive regulation of gene expression 4.32E-05 21 13 6.14E-07 40 28 3 10.71428571 4 GO:0009888 tissue development 4.99E-05 41 30 7.34E-07 42 28 3 10.71428571 31 GO:0007399 nervous system development 3.00E-10 76 47 2.06E-14 106 84 9 10.71428571 31 GO:0009968 negative regulation of signal transduction 1.70E-03 18 11 1.43E-07 33 28 3 10.71428571 3 GO:0050789 regulation of biological process 9.49E-12 161 120 1.26E-43 599 393 42 10.6870229 11 GO:0080090 regulation of primary metabolic process 5.31E-06 57 44 1.16E-09 338 226 24 10.61946903 3 GO:0060255 regulation of macromolecule metabolic process 7.19E-06 56 40 1.63E-13 228 142 15 10.56338028 18 GO:0051234 establishment of localization 2.63E-04 164 112 4.15E-04 204 142 15 10.56338028 4 GO:0007165 signal transduction 3.57E-08 68 57 5.94E-16 223 161 17 10.55900621 3 GO:0042330 taxis 2.99E-04 15 12 4.36E-10 49 38 4 10.52631579 3 GO:0044456 synapse part 4.89E-04 13 11 2.24E-04 23 19 2 10.52631579 4 GO:0045944 positive regulation of transcription from RNA polymerase II promoter 3.99E-06 19 14 2.93E-05 25 19 2 10.52631579 11 GO:0060322 head development 4.58E-04 12 11 3.76E-04 19 19 2 10.52631579 41 GO:0022603 regulation of anatomical structure morphogenesis 1.59E-03 20 13 2.28E-04 22 19 2 10.52631579 11 GO:0007610 behavior 1.33E-04 34 24 2.67E-23 244 172 18 10.46511628 31 GO:0007010 cytoskeleton organization 1.13E-04 42 24 2.87E-05 86 48 5 10.41666667 37 GO:0044425 membrane part 9.11E-05 147 96 6.46E-12 713 462 48 10.38961039 3 GO:0048598 embryonic morphogenesis 1.05E-04 22 12 1.10E-09 49 29 3 10.34482759 4 GO:0048858 cell projection morphogenesis 7.73E-04 17 14 1.76E-06 37 29 3 10.34482759 4 GO:0032990 cell part morphogenesis 1.01E-03 17 14 3.48E-06 37 29 3 10.34482759 11 GO:0044212 transcription regulatory region DNA binding 1.71E-05 12 9 1.41E-11 44 29 3 10.34482759 11 GO:0000975 regulatory region DNA binding 2.19E-05 12 9 2.38E-11 44 29 3 10.34482759 11 GO:0001067 regulatory region nucleic acid binding 2.19E-05 12 9 2.38E-11 44 29 3 10.34482759 22 GO:0048598 embryonic morphogenesis 5.39E-07 17 14 3.59E-08 48 29 3 10.34482759 31 GO:0051254 positive regulation of RNA metabolic process 2.17E-06 38 27 1.71E-09 45 29 3 10.34482759 31 GO:0010648 negative regulation of cell communication 2.02E-04 22 14 2.42E-07 34 29 3 10.34482759 31 GO:0023057 negative regulation of signaling 4.83E-04 21 14 2.42E-07 34 29 3 10.34482759 31 GO:0030036 actin cytoskeleton organization 3.91E-05 26 16 1.97E-03 50 29 3 10.34482759 31 GO:0010646 regulation of cell communication 3.49E-06 54 35 4.21E-11 90 68 7 10.29411765 4 GO:0050896 response to stimulus 3.79E-06 99 77 2.18E-13 295 214 22 10.28037383 4 GO:0030030 cell projection organization 2.35E-04 23 18 4.98E-06 51 39 4 10.25641026 41 GO:0031224 intrinsic component of membrane 6.82E-04 91 60 4.30E-05 335 225 23 10.22222222 4 GO:0030182 neuron differentiation 4.69E-08 32 23 7.10E-10 62 49 5 10.20408163 37 GO:0048585 negative regulation of response to stimulus 4.11E-06 32 20 5.90E-10 64 49 5 10.20408163 37 GO:0044877 macromolecular complex binding 1.40E-03 30 18 8.41E-07 66 49 5 10.20408163 14 GO:0071944 cell periphery 3.60E-04 54 34 2.25E-12 83 59 6 10.16949153 31 GO:0007186 G-protein coupled receptor signaling pathway 4.02E-05 24 20 1.45E-12 91 69 7 10.14492754 31 GO:0023051 regulation of signaling 3.49E-06 54 35 3.20E-11 90 69 7 10.14492754 3 GO:0065007 biological regulation 2.50E-11 164 122 5.25E-31 652 416 42 10.09615385 4 GO:0006357 regulation of transcription from RNA polymerase II promoter 5.77E-09 32 24 4.42E-13 59 40 4 10 4 GO:0097458 neuron part 9.31E-04 20 15 1.53E-12 63 50 5 10 4 GO:1902680 positive regulation of RNA biosynthetic process 9.05E-06 23 17 6.25E-05 27 20 2 10 4 GO:1903508 positive regulation of nucleic acid-templated transcription 2.57E-06 23 17 1.17E-04 26 20 2 10 4 GO:0045893 "positive regulation of transcription, DNA-templated" 2.57E-06 23 17 1.17E-04 26 20 2 10 11 GO:0009605 response to external stimulus 4.83E-06 28 22 1.55E-10 132 100 10 10 11 GO:0048732 gland development 9.77E-05 11 5 3.84E-03 12 10 1 10 18 GO:0005912 adherens junction 2.12E-05 15 11 5.06E-09 14 10 1 10 18 GO:0070161 anchoring junction 2.76E-05 15 11 1.32E-08 14 10 1 10 31 GO:0005886 plasma membrane 2.39E-05 70 43 9.36E-25 171 110 11 10 31 GO:0044459 plasma membrane part 2.82E-04 43 27 1.53E-15 87 60 6 10 31 GO:0045935 positive regulation of nucleobase-containing compound metabolic process 4.06E-06 39 27 5.15E-09 46 30 3 10 31 GO:0031672 A band 1.54E-03 8 6 1.24E-06 14 10 1 10 31 GO:0022603 regulation of anatomical structure morphogenesis 8.72E-06 24 15 4.94E-06 25 20 2 10 31 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding 3.04E-06 9 6 1.23E-05 15 10 1 10 41 GO:0004888 transmembrane signaling receptor activity 1.15E-03 22 14 2.52E-04 78 60 6 10 41 GO:0016021 integral component of membrane 1.14E-03 89 59 1.34E-04 330 221 22 9.954751131 4 GO:0051716 cellular response to stimulus 1.38E-05 72 59 2.90E-13 237 171 17 9.941520468 31 GO:0071944 cell periphery 2.29E-06 79 48 6.47E-26 188 121 12 9.917355372 3 GO:0005886 plasma membrane 1.26E-04 36 25 1.36E-20 151 101 10 9.900990099 11 GO:0060255 regulation of macromolecule metabolic process 2.23E-05 58 46 2.84E-09 373 243 24 9.87654321 3 GO:0071944 cell periphery 3.02E-06 43 29 9.10E-23 169 112 11 9.821428571 11 GO:0006366 transcription from RNA polymerase II promoter 4.63E-05 27 20 4.74E-13 115 82 8 9.756097561 11 GO:0019222 regulation of metabolic process 2.07E-06 68 52 6.54E-11 437 289 28 9.688581315 3 GO:0007166 cell surface receptor signaling pathway 6.64E-05 31 21 1.48E-14 125 93 9 9.677419355 3 GO:0065009 regulation of molecular function 4.11E-04 23 16 9.62E-13 87 62 6 9.677419355 11 GO:0006935 chemotaxis 1.57E-05 17 14 4.89E-11 74 62 6 9.677419355 31 GO:0051173 positive regulation of nitrogen compound metabolic process 3.79E-06 40 27 1.17E-09 48 31 3 9.677419355 4 GO:0009987 cellular process 1.72E-04 209 154 6.47E-19 690 456 44 9.649122807 18 GO:0006810 transport 5.89E-04 156 106 1.32E-03 194 135 13 9.62962963 4 GO:0048699 generation of neurons 2.63E-09 36 26 7.30E-10 65 52 5 9.615384615 11 GO:0046872 metal ion binding 1.19E-06 53 41 7.79E-10 497 312 30 9.615384615 11 GO:0043169 cation binding 2.49E-06 53 41 5.71E-10 500 314 30 9.554140127 4 GO:0044700 single organism signaling 6.93E-08 74 62 4.36E-20 247 178 17 9.550561798 4 GO:0023052 signaling 6.45E-08 75 63 4.69E-20 247 178 17 9.550561798 4 GO:2000113 negative regulation of cellular macromolecule biosynthetic process 8.83E-06 19 15 6.06E-08 32 21 2 9.523809524 4 GO:0010558 negative regulation of macromolecule biosynthetic process 1.04E-05 19 15 6.06E-08 32 21 2 9.523809524 4 GO:0051254 positive regulation of RNA metabolic process 1.56E-05 23 17 4.18E-05 28 21 2 9.523809524 11 GO:0042330 taxis 1.97E-05 18 15 2.10E-10 76 63 6 9.523809524 11 GO:0048729 tissue morphogenesis 1.49E-04 30 20 2.10E-09 53 42 4 9.523809524 31 GO:0000904 cell morphogenesis involved in differentiation 1.65E-08 38 23 9.13E-12 52 42 4 9.523809524 3 GO:0005488 binding 1.33E-04 160 117 2.52E-14 720 463 44 9.503239741 3 GO:0050896 response to stimulus 7.93E-07 91 67 8.27E-18 380 264 25 9.46969697 4 GO:0022008 neurogenesis 4.50E-08 37 27 2.45E-09 66 53 5 9.433962264 22 GO:0003677 DNA binding 1.30E-05 21 16 1.11E-09 171 106 10 9.433962264 37 GO:0016021 integral component of membrane 1.04E-05 114 77 2.99E-09 642 404 38 9.405940594 4 GO:0007154 cell communication 1.18E-08 78 64 8.19E-21 252 182 17 9.340659341 31 GO:0048699 generation of neurons 1.30E-12 62 39 5.87E-14 92 75 7 9.333333333 4 GO:0032989 cellular component morphogenesis 6.81E-05 27 20 1.91E-05 66 43 4 9.302325581 37 GO:0031224 intrinsic component of membrane 1.02E-05 115 77 5.30E-10 649 410 38 9.268292683 3 GO:0006928 movement of cell or subcellular component 2.06E-05 29 23 2.52E-13 106 76 7 9.210526316 31 GO:0022008 neurogenesis 1.27E-10 64 40 5.38E-13 93 76 7 9.210526316 4 GO:0048519 negative regulation of biological process 1.87E-04 52 37 1.34E-09 124 87 8 9.195402299 18 GO:1902578 single-organism localization 2.77E-05 127 82 3.37E-04 140 98 9 9.183673469 31 GO:0051179 localization 6.14E-07 171 119 1.51E-05 452 274 25 9.124087591 3 GO:0097458 neuron part 1.59E-04 20 16 2.65E-14 77 66 6 9.090909091 3 GO:0048522 positive regulation of cellular process 1.99E-04 40 23 6.58E-09 96 66 6 9.090909091 4 GO:0071944 cell periphery 9.22E-05 43 27 5.84E-16 128 88 8 9.090909091 4 GO:0051239 regulation of multicellular organismal process 1.10E-06 53 37 1.50E-12 138 99 9 9.090909091 4 GO:0031327 negative regulation of cellular biosynthetic process 1.14E-05 19 15 2.41E-08 33 22 2 9.090909091 4 GO:0001012 RNA polymerase II regulatory region DNA binding 5.18E-04 5 5 2.84E-08 17 11 1 9.090909091 4 GO:0009890 negative regulation of biosynthetic process 1.34E-05 19 15 3.40E-08 33 22 2 9.090909091 4 GO:0000902 cell morphogenesis 3.67E-04 22 17 7.64E-07 43 33 3 9.090909091 4 GO:0009968 negative regulation of signal transduction 1.08E-03 12 12 2.09E-06 25 22 2 9.090909091 4 GO:0010648 negative regulation of cell communication 3.34E-04 14 13 7.32E-06 25 22 2 9.090909091 4 GO:0023057 negative regulation of signaling 1.02E-03 13 13 7.32E-06 25 22 2 9.090909091 4 GO:0051173 positive regulation of nitrogen compound metabolic process 7.27E-05 23 17 3.28E-05 30 22 2 9.090909091 4 GO:0045935 positive regulation of nucleobase-containing compound metabolic process 4.29E-05 23 17 5.44E-05 29 22 2 9.090909091 11 GO:0009887 organ morphogenesis 1.83E-05 23 16 5.77E-14 66 55 5 9.090909091 11 GO:0045595 regulation of cell differentiation 1.45E-06 22 15 6.10E-12 67 55 5 9.090909091 11 GO:0009893 positive regulation of metabolic process 4.47E-04 30 22 3.27E-08 121 88 8 9.090909091 14 GO:0002009 morphogenesis of an epithelium 9.13E-05 39 26 1.52E-05 16 11 1 9.090909091 27 GO:0043565 sequence-specific DNA binding 8.23E-07 15 12 9.53E-05 12 11 1 9.090909091 31 GO:0001012 RNA polymerase II regulatory region DNA binding 3.04E-06 9 6 1.37E-07 19 11 1 9.090909091 31 GO:0004871 signal transducer activity 2.36E-06 40 31 3.18E-07 143 99 9 9.090909091 31 GO:0010769 regulation of cell morphogenesis involved in differentiation 2.41E-04 11 6 6.89E-05 12 11 1 9.090909091 31 GO:0044425 membrane part 6.80E-06 124 83 1.39E-07 370 232 21 9.051724138 3 GO:0040011 locomotion 2.37E-07 77 56 1.24E-18 316 211 19 9.004739336 3 GO:0007165 signal transduction 8.24E-07 58 41 1.80E-17 275 189 17 8.994708995 11 GO:0009888 tissue development 7.01E-05 39 26 4.36E-16 103 78 7 8.974358974 11 GO:0006357 regulation of transcription from RNA polymerase II promoter 3.28E-06 26 20 4.89E-15 110 78 7 8.974358974 31 GO:0004872 receptor activity 2.65E-08 50 37 2.48E-04 120 78 7 8.974358974 21 GO:0003677 DNA binding 3.60E-06 26 20 1.55E-05 74 56 5 8.928571429 11 GO:0007155 cell adhesion 1.30E-04 13 9 5.51E-15 58 45 4 8.888888889 11 GO:0022610 biological adhesion 1.30E-04 13 9 2.64E-14 58 45 4 8.888888889 31 GO:0007166 cell surface receptor signaling pathway 9.94E-09 68 49 1.14E-17 142 102 9 8.823529412 31 GO:0007411 axon guidance 1.25E-07 24 18 1.21E-09 39 34 3 8.823529412 31 GO:0097485 neuron projection guidance 1.51E-07 24 18 1.55E-09 39 34 3 8.823529412 21 GO:0005634 nucleus 2.70E-05 47 36 1.60E-05 122 91 8 8.791208791 3 GO:0007154 cell communication 1.08E-07 68 46 1.74E-19 299 205 18 8.780487805 4 GO:0007399 nervous system development 1.20E-07 43 31 7.89E-10 74 57 5 8.771929825 37 GO:0005509 calcium ion binding 1.26E-04 22 14 2.08E-09 82 57 5 8.771929825 22 GO:2000112 regulation of cellular macromolecule biosynthetic process 8.76E-05 22 15 8.43E-10 172 103 9 8.737864078 11 GO:0040011 locomotion 9.26E-10 89 63 9.63E-20 554 368 32 8.695652174 22 GO:0003676 nucleic acid binding 1.09E-05 31 22 1.86E-05 245 161 14 8.695652174 3 GO:0005623 cell 3.51E-04 164 115 7.29E-21 668 451 39 8.647450111 3 GO:0043005 neuron projection 2.82E-04 17 13 7.54E-13 64 58 5 8.620689655 4 GO:0042995 cell projection 1.18E-03 24 17 1.17E-07 69 58 5 8.620689655 3 GO:0048699 generation of neurons 3.21E-04 23 17 2.33E-13 85 70 6 8.571428571 4 GO:0042221 response to chemical 2.67E-04 41 31 6.77E-04 98 70 6 8.571428571 31 GO:0048585 negative regulation of response to stimulus 2.06E-03 21 12 4.18E-09 41 35 3 8.571428571 4 GO:0044763 single-organism cellular process 9.93E-06 158 121 2.37E-17 563 376 32 8.510638298 3 GO:0022008 neurogenesis 4.96E-04 25 18 6.23E-13 87 71 6 8.450704225 3 GO:0044700 single organism signaling 1.51E-07 66 45 1.25E-19 296 203 17 8.374384236 3 GO:0023052 signaling 2.89E-07 66 45 1.36E-19 296 203 17 8.374384236 3 GO:0051716 cellular response to stimulus 4.34E-05 63 43 1.33E-14 294 203 17 8.374384236 3 GO:0010604 positive regulation of macromolecule metabolic process 3.81E-04 25 14 3.08E-07 51 36 3 8.333333333 3 GO:1902680 positive regulation of RNA biosynthetic process 1.17E-04 19 12 2.88E-06 35 24 2 8.333333333 3 GO:1903508 positive regulation of nucleic acid-templated transcription 4.28E-05 19 12 5.00E-06 34 24 2 8.333333333 3 GO:0045893 "positive regulation of transcription, DNA-templated" 4.28E-05 19 12 5.00E-06 34 24 2 8.333333333 3 GO:0051254 positive regulation of RNA metabolic process 1.81E-04 19 12 6.05E-06 35 24 2 8.333333333 4 GO:0045664 regulation of neuron differentiation 4.25E-05 11 7 1.35E-04 13 12 1 8.333333333 21 GO:0009893 positive regulation of metabolic process 2.90E-04 20 16 1.81E-05 36 24 2 8.333333333 27 GO:0006355 "regulation of transcription, DNA-templated" 1.01E-05 22 17 8.88E-05 16 12 1 8.333333333 27 GO:1903506 regulation of nucleic acid-templated transcription 1.01E-05 22 17 8.88E-05 16 12 1 8.333333333 27 GO:2001141 regulation of RNA biosynthetic process 1.62E-05 22 17 9.44E-05 16 12 1 8.333333333 27 GO:0051252 regulation of RNA metabolic process 4.25E-05 22 17 1.12E-04 16 12 1 8.333333333 27 GO:0006351 "transcription, DNA-templated" 2.94E-05 24 18 1.65E-04 16 12 1 8.333333333 27 GO:0097659 nucleic acid-templated transcription 2.94E-05 24 18 1.76E-04 16 12 1 8.333333333 27 GO:0019219 regulation of nucleobase-containing compound metabolic process 4.56E-05 23 18 1.78E-04 16 12 1 8.333333333 27 GO:0051171 regulation of nitrogen compound metabolic process 7.08E-05 23 18 1.93E-04 16 12 1 8.333333333 27 GO:0032774 RNA biosynthetic process 1.40E-05 25 18 2.02E-04 16 12 1 8.333333333 11 GO:0007399 nervous system development 3.81E-06 38 27 1.94E-24 183 145 12 8.275862069 11 GO:0048869 cellular developmental process 1.03E-04 54 38 7.99E-13 371 256 21 8.203125 11 GO:0030154 cell differentiation 6.55E-05 52 36 4.27E-12 354 244 20 8.196721311 11 GO:0005488 binding 2.55E-04 171 116 3.37E-14 1345 843 69 8.185053381 4 GO:0007186 G-protein coupled receptor signaling pathway 4.48E-04 14 12 4.70E-08 62 49 4 8.163265306 11 GO:0010557 positive regulation of macromolecule biosynthetic process 3.34E-04 20 14 2.60E-09 67 49 4 8.163265306 11 GO:0044707 single-multicellular organism process 7.08E-04 149 107 2.64E-03 1169 726 59 8.126721763 31 GO:0007409 axonogenesis 2.50E-08 31 20 1.02E-10 46 37 3 8.108108108 21 GO:0040011 locomotion 8.03E-06 48 35 3.48E-08 138 99 8 8.080808081 4 GO:0048523 negative regulation of cellular process 1.17E-04 41 31 8.39E-12 90 62 5 8.064516129 31 GO:0016021 integral component of membrane 5.12E-05 90 62 4.77E-05 325 199 16 8.040201005 3 GO:0048731 system development 2.05E-04 69 45 3.64E-17 272 187 15 8.021390374 3 GO:0001708 cell fate specification 5.28E-04 10 7 5.28E-09 38 25 2 8 4 GO:0060089 molecular transducer activity 7.65E-06 31 25 4.65E-06 108 75 6 8 11 GO:0007411 axon guidance 1.56E-06 15 12 3.17E-11 58 50 4 8 11 GO:0097485 neuron projection guidance 1.77E-06 15 12 4.66E-11 58 50 4 8 11 GO:0009891 positive regulation of biosynthetic process 2.52E-04 21 15 1.90E-09 69 50 4 8 11 GO:0031328 positive regulation of cellular biosynthetic process 2.28E-04 21 15 1.90E-09 69 50 4 8 31 GO:0045944 positive regulation of transcription from RNA polymerase II promoter 6.76E-06 28 20 1.44E-09 40 25 2 8 11 GO:1901363 heterocyclic compound binding 2.25E-04 93 66 8.95E-08 744 463 37 7.991360691 11 GO:0097159 organic cyclic compound binding 2.56E-04 93 66 7.73E-08 747 465 37 7.956989247 31 GO:0031224 intrinsic component of membrane 1.54E-05 93 63 1.89E-05 329 202 16 7.920792079 11 GO:0050789 regulation of biological process 1.84E-06 155 110 1.76E-49 1060 708 56 7.90960452 4 GO:0005886 plasma membrane 8.85E-04 37 22 1.42E-13 112 76 6 7.894736842 31 GO:0048667 cell morphogenesis involved in neuron differentiation 1.77E-07 32 20 2.36E-10 47 38 3 7.894736842 11 GO:0050794 regulation of cellular process 1.36E-08 116 83 7.28E-45 878 598 47 7.859531773 11 GO:0048513 organ development 3.80E-05 66 46 2.24E-07 347 233 18 7.725321888 3 GO:0016477 cell migration 4.39E-04 20 15 3.86E-10 76 52 4 7.692307692 3 GO:0045935 positive regulation of nucleobase-containing compound metabolic process 4.05E-04 19 12 4.21E-06 37 26 2 7.692307692 4 GO:0030017 sarcomere 8.75E-04 9 5 3.75E-06 21 13 1 7.692307692 11 GO:0000976 transcription regulatory region sequence-specific DNA binding 2.81E-05 9 7 2.32E-11 37 26 2 7.692307692 11 GO:0010628 positive regulation of gene expression 3.88E-04 20 14 4.51E-10 71 52 4 7.692307692 11 GO:0045664 regulation of neuron differentiation 6.72E-07 13 10 2.17E-09 30 26 2 7.692307692 11 GO:0050770 regulation of axonogenesis 8.51E-05 7 6 4.26E-04 14 13 1 7.692307692 21 GO:0006355 "regulation of transcription, DNA-templated" 5.03E-06 27 20 6.83E-07 74 52 4 7.692307692 21 GO:1903506 regulation of nucleic acid-templated transcription 5.03E-06 27 20 6.83E-07 74 52 4 7.692307692 21 GO:2001141 regulation of RNA biosynthetic process 8.81E-06 27 20 8.33E-07 74 52 4 7.692307692 21 GO:0051252 regulation of RNA metabolic process 3.24E-06 29 21 1.43E-06 74 52 4 7.692307692 21 GO:0019219 regulation of nucleobase-containing compound metabolic process 5.03E-06 30 22 6.20E-06 74 52 4 7.692307692 21 GO:0009891 positive regulation of biosynthetic process 1.01E-04 15 12 2.80E-04 19 13 1 7.692307692 21 GO:0031328 positive regulation of cellular biosynthetic process 3.28E-04 14 12 2.80E-04 19 13 1 7.692307692 21 GO:0010557 positive regulation of macromolecule biosynthetic process 2.05E-04 14 11 5.12E-04 18 13 1 7.692307692 27 GO:0031323 regulation of cellular metabolic process 2.33E-04 27 20 1.81E-04 19 13 1 7.692307692 27 GO:0010468 regulation of gene expression 3.04E-04 23 17 1.89E-04 18 13 1 7.692307692 18 GO:0044765 single-organism transport 1.54E-04 118 76 6.35E-04 131 92 7 7.608695652 11 GO:0065007 biological regulation 4.35E-06 158 112 1.74E-33 1178 750 57 7.6 21 GO:0006351 "transcription, DNA-templated" 2.01E-04 27 20 1.30E-06 76 53 4 7.547169811 21 GO:0097659 nucleic acid-templated transcription 2.01E-04 27 20 1.63E-06 76 53 4 7.547169811 21 GO:0051171 regulation of nitrogen compound metabolic process 8.88E-06 30 22 2.19E-06 76 53 4 7.547169811 21 GO:0032774 RNA biosynthetic process 2.87E-04 27 20 2.54E-06 76 53 4 7.547169811 21 GO:0002119 nematode larval development 6.29E-04 45 33 5.14E-06 145 106 8 7.547169811 31 GO:0000902 cell morphogenesis 4.63E-06 41 25 8.22E-12 66 53 4 7.547169811 21 GO:0009791 post-embryonic development 6.52E-04 47 33 8.28E-06 146 107 8 7.476635514 3 GO:0051173 positive regulation of nitrogen compound metabolic process 2.27E-04 20 12 1.06E-06 39 27 2 7.407407407 21 GO:0031326 regulation of cellular biosynthetic process 1.86E-06 31 24 1.18E-06 79 54 4 7.407407407 21 GO:2000112 regulation of cellular macromolecule biosynthetic process 5.92E-06 29 22 1.42E-06 78 54 4 7.407407407 21 GO:0009889 regulation of biosynthetic process 6.90E-07 32 24 1.48E-06 79 54 4 7.407407407 21 GO:0010556 regulation of macromolecule biosynthetic process 1.29E-06 31 23 1.90E-06 78 54 4 7.407407407 21 GO:0003676 nucleic acid binding 6.17E-06 38 29 1.69E-04 110 81 6 7.407407407 11 GO:0048731 system development 1.82E-05 78 54 1.15E-13 453 311 23 7.395498392 3 GO:0048869 cellular developmental process 3.06E-04 49 33 3.95E-14 219 149 11 7.382550336 11 GO:0048699 generation of neurons 3.09E-06 29 21 4.12E-21 153 122 9 7.37704918 31 GO:0030182 neuron differentiation 9.48E-10 53 32 2.49E-12 84 68 5 7.352941176 31 GO:0048812 neuron projection morphogenesis 1.77E-07 32 20 1.37E-11 50 41 3 7.317073171 11 GO:0043167 ion binding 5.39E-05 78 56 3.77E-12 774 482 35 7.261410788 47 GO:0046872 metal ion binding 1.11E-04 25 20 4.76E-05 176 111 8 7.207207207 11 GO:0022008 neurogenesis 8.09E-06 31 22 2.33E-20 157 125 9 7.2 4 GO:0048585 negative regulation of response to stimulus 8.85E-05 16 14 1.27E-07 31 28 2 7.142857143 4 GO:0050767 regulation of neurogenesis 3.73E-05 12 8 2.66E-05 15 14 1 7.142857143 11 GO:0010648 negative regulation of cell communication 6.64E-04 13 7 9.27E-10 54 42 3 7.142857143 11 GO:0051128 regulation of cellular component organization 1.13E-03 24 16 3.69E-04 95 70 5 7.142857143 21 GO:0016477 cell migration 5.88E-04 14 11 2.37E-06 37 28 2 7.142857143 21 GO:0034654 nucleobase-containing compound biosynthetic process 3.66E-04 30 21 1.32E-05 82 56 4 7.142857143 21 GO:0019438 aromatic compound biosynthetic process 2.80E-04 31 22 3.45E-05 82 56 4 7.142857143 21 GO:0044271 cellular nitrogen compound biosynthetic process 4.04E-04 31 22 3.88E-05 83 56 4 7.142857143 21 GO:0018130 heterocycle biosynthetic process 6.95E-04 30 21 5.16E-05 82 56 4 7.142857143 21 GO:1901362 organic cyclic compound biosynthetic process 5.45E-04 31 22 1.05E-04 82 56 4 7.142857143 27 GO:0080090 regulation of primary metabolic process 3.15E-04 26 20 3.28E-05 20 14 1 7.142857143 31 GO:0061564 axon development 1.11E-08 33 21 7.55E-08 55 42 3 7.142857143 31 GO:0007423 sensory organ development 5.63E-04 20 7 1.40E-03 14 14 1 7.142857143 37 GO:0009886 post-embryonic morphogenesis 8.78E-05 19 11 6.23E-04 20 14 1 7.142857143 47 GO:0043169 cation binding 1.63E-04 25 20 4.31E-05 177 112 8 7.142857143 11 GO:0050896 response to stimulus 2.00E-05 92 66 1.74E-23 699 477 34 7.1278826 11 GO:0044699 single-organism process 4.98E-04 208 147 4.47E-15 1876 1159 82 7.075064711 11 GO:0007409 axonogenesis 2.02E-06 18 14 1.14E-12 69 57 4 7.01754386 21 GO:0010468 regulation of gene expression 8.31E-06 32 23 1.21E-04 81 57 4 7.01754386 3 GO:0030154 cell differentiation 4.36E-04 46 30 1.17E-13 210 143 10 6.993006993 41 GO:0004930 G-protein coupled receptor activity 1.65E-03 13 9 2.65E-05 55 43 3 6.976744186 4 GO:0031324 negative regulation of cellular metabolic process 2.72E-04 22 17 2.48E-07 48 29 2 6.896551724 11 GO:0016477 cell migration 7.98E-06 25 20 1.34E-11 127 87 6 6.896551724 11 GO:0050767 regulation of neurogenesis 6.75E-07 14 10 5.24E-10 33 29 2 6.896551724 31 GO:0048666 neuron development 2.49E-08 43 26 3.82E-10 72 58 4 6.896551724 22 GO:0001071 nucleic acid binding transcription factor activity 1.59E-06 14 11 1.82E-11 119 73 5 6.849315068 22 GO:0003700 sequence-specific DNA binding transcription factor activity 1.50E-06 14 11 1.82E-11 119 73 5 6.849315068 3 GO:0044763 single-organism cellular process 5.65E-05 137 95 3.46E-25 731 468 32 6.837606838 11 GO:0051674 localization of cell 4.80E-06 26 20 1.74E-11 129 88 6 6.818181818 11 GO:0048870 cell motility 1.37E-05 25 20 1.74E-11 129 88 6 6.818181818 31 GO:0048858 cell projection morphogenesis 9.83E-06 32 20 3.55E-10 55 44 3 6.818181818 31 GO:0032990 cell part morphogenesis 1.64E-05 32 20 1.08E-09 55 44 3 6.818181818 47 GO:0007610 behavior 3.12E-04 18 14 2.77E-19 112 74 5 6.756756757 4 GO:0051960 regulation of nervous system development 2.37E-06 15 10 1.23E-05 17 15 1 6.666666667 4 GO:0060429 epithelium development 1.05E-03 32 24 1.04E-04 26 15 1 6.666666667 11 GO:0023052 signaling 2.48E-05 64 47 9.11E-34 562 390 26 6.666666667 11 GO:0010769 regulation of cell morphogenesis involved in differentiation 1.64E-05 9 7 9.83E-05 16 15 1 6.666666667 18 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity 9.99E-05 17 11 1.51E-08 21 15 1 6.666666667 31 GO:0038023 signaling receptor activity 1.80E-05 30 22 5.49E-04 113 75 5 6.666666667 37 GO:0030855 epithelial cell differentiation 5.84E-05 23 10 1.33E-04 22 15 1 6.666666667 11 GO:0007154 cell communication 2.21E-05 65 48 5.52E-33 566 391 26 6.649616368 11 GO:0050793 regulation of developmental process 3.99E-05 45 32 1.81E-15 271 181 12 6.629834254 22 GO:0009653 anatomical structure morphogenesis 1.47E-05 37 28 3.61E-15 248 167 11 6.586826347 21 GO:0005622 intracellular 6.65E-04 91 68 5.12E-11 273 198 13 6.565656566 11 GO:0048667 cell morphogenesis involved in neuron differentiation 1.32E-05 18 14 2.49E-13 73 61 4 6.557377049 4 GO:0051179 localization 4.47E-04 86 64 1.09E-04 324 199 13 6.532663317 11 GO:0060429 epithelium development 8.71E-04 31 18 1.94E-10 64 46 3 6.52173913 11 GO:1902680 positive regulation of RNA biosynthetic process 9.16E-04 18 13 6.92E-10 64 46 3 6.52173913 11 GO:1903508 positive regulation of nucleic acid-templated transcription 3.79E-04 18 13 7.96E-10 63 46 3 6.52173913 11 GO:0045893 "positive regulation of transcription, DNA-templated" 3.79E-04 18 13 7.96E-10 63 46 3 6.52173913 11 GO:0044700 single organism signaling 1.00E-04 61 45 7.72E-34 562 390 25 6.41025641 11 GO:0006928 movement of cell or subcellular component 3.79E-05 30 25 1.98E-14 175 126 8 6.349206349 11 GO:0048812 neuron projection morphogenesis 1.32E-05 18 14 2.78E-14 76 64 4 6.25 11 GO:0090596 sensory organ morphogenesis 4.04E-04 10 5 5.75E-06 16 16 1 6.25 11 GO:0010975 regulation of neuron projection development 2.81E-05 9 7 3.63E-05 18 16 1 6.25 21 GO:0031323 regulation of cellular metabolic process 8.59E-06 37 28 1.30E-06 95 64 4 6.25 21 GO:0032502 developmental process 6.49E-04 88 64 1.08E-04 294 208 13 6.25 27 GO:0048869 cellular developmental process 2.07E-04 27 21 6.21E-06 22 16 1 6.25 31 GO:0032989 cellular component morphogenesis 3.73E-07 50 30 7.57E-08 95 64 4 6.25 11 GO:0007165 signal transduction 9.78E-05 55 41 1.68E-27 514 355 22 6.197183099 31 GO:0048468 cell development 5.38E-07 78 48 1.36E-05 159 113 7 6.194690265 11 GO:0051716 cellular response to stimulus 8.80E-04 62 46 2.56E-22 552 375 23 6.133333333 11 GO:0030182 neuron differentiation 4.43E-05 25 18 6.30E-20 143 115 7 6.086956522 11 GO:2000026 regulation of multicellular organismal development 5.46E-06 29 22 5.97E-09 130 99 6 6.060606061 11 GO:0002009 morphogenesis of an epithelium 6.04E-04 27 17 1.10E-07 43 33 2 6.060606061 21 GO:0080090 regulation of primary metabolic process 3.60E-06 37 28 1.19E-07 96 66 4 6.060606061 11 GO:0044763 single-organism cellular process 9.73E-04 141 99 1.20E-33 1376 878 53 6.036446469 21 GO:0019222 regulation of metabolic process 2.61E-06 43 32 5.00E-08 120 83 5 6.024096386 31 GO:0031175 neuron projection development 2.72E-07 36 23 1.36E-08 64 50 3 6 11 GO:0060089 molecular transducer activity 3.13E-04 26 20 7.82E-12 262 184 11 5.97826087 11 GO:0000904 cell morphogenesis involved in differentiation 1.39E-05 20 14 1.71E-15 81 67 4 5.970149254 11 GO:0061564 axon development 5.64E-06 18 14 2.69E-10 89 67 4 5.970149254 3 GO:0000976 transcription regulatory region sequence-specific DNA binding 1.06E-04 8 4 3.66E-09 24 17 1 5.882352941 11 GO:0051960 regulation of nervous system development 1.21E-06 15 11 9.03E-12 39 34 2 5.882352941 11 GO:0022604 regulation of cell morphogenesis 1.17E-05 12 9 1.91E-03 20 17 1 5.882352941 21 GO:0060255 regulation of macromolecule metabolic process 2.87E-06 39 29 8.43E-06 98 68 4 5.882352941 21 GO:0010604 positive regulation of macromolecule metabolic process 2.24E-04 18 14 2.36E-04 24 17 1 5.882352941 31 GO:0002009 morphogenesis of an epithelium 8.96E-07 56 37 1.12E-03 22 17 1 5.882352941 21 GO:0044699 single-organism process 2.88E-05 122 91 1.00E-05 428 290 17 5.862068966 11 GO:0000902 cell morphogenesis 6.22E-05 23 17 8.81E-16 105 86 5 5.813953488 47 GO:0044706 multi-multicellular organism process 2.27E-04 14 10 4.91E-14 81 52 3 5.769230769 21 GO:0005488 binding 3.60E-04 98 73 6.94E-10 333 228 13 5.701754386 11 GO:0048468 cell development 6.73E-04 37 23 1.96E-07 274 193 11 5.699481865 21 GO:0050789 regulation of biological process 3.94E-04 84 59 6.54E-15 252 176 10 5.681818182 3 GO:0044212 transcription regulatory region DNA binding 4.14E-05 11 7 2.76E-09 28 18 1 5.555555556 3 GO:0000975 regulatory region DNA binding 9.56E-06 12 8 3.74E-09 28 18 1 5.555555556 3 GO:0001067 regulatory region nucleic acid binding 9.56E-06 12 8 3.74E-09 28 18 1 5.555555556 21 GO:2000026 regulation of multicellular organismal development 1.92E-04 17 15 4.62E-08 44 36 2 5.555555556 22 GO:0044212 transcription regulatory region DNA binding 1.84E-06 9 6 1.42E-08 28 18 1 5.555555556 22 GO:0000975 regulatory region DNA binding 2.25E-06 9 6 1.91E-08 28 18 1 5.555555556 22 GO:0001067 regulatory region nucleic acid binding 2.25E-06 9 6 1.91E-08 28 18 1 5.555555556 21 GO:1901363 heterocyclic compound binding 2.13E-04 56 38 1.18E-05 187 128 7 5.46875 21 GO:0097159 organic cyclic compound binding 2.35E-04 56 38 1.49E-05 187 128 7 5.46875 4 GO:0004871 signal transducer activity 1.02E-03 20 15 9.03E-06 103 74 4 5.405405405 21 GO:0005515 protein binding 4.55E-06 61 49 8.64E-11 149 111 6 5.405405405 47 GO:0071944 cell periphery 4.79E-06 25 18 2.65E-15 114 74 4 5.405405405 11 GO:0007166 cell surface receptor signaling pathway 6.55E-04 30 22 3.74E-32 250 187 10 5.347593583 11 GO:0048858 cell projection morphogenesis 1.40E-04 18 14 8.78E-15 90 75 4 5.333333333 11 GO:0032990 cell part morphogenesis 1.90E-04 18 14 6.47E-14 90 75 4 5.333333333 11 GO:0032989 cellular component morphogenesis 7.13E-05 26 18 2.42E-10 158 113 6 5.309734513 21 GO:0065007 biological regulation 5.10E-04 86 61 2.29E-12 283 189 10 5.291005291 3 GO:0040012 regulation of locomotion 1.36E-04 20 15 2.49E-10 48 38 2 5.263157895 4 GO:0044449 contractile fiber part 1.07E-03 10 6 1.21E-05 29 19 1 5.263157895 11 GO:0060284 regulation of cell development 7.13E-06 14 10 7.40E-13 43 38 2 5.263157895 11 GO:0031344 regulation of cell projection organization 7.30E-04 9 7 1.46E-04 21 19 1 5.263157895 31 GO:0030030 cell projection organization 1.11E-05 41 25 1.50E-08 73 57 3 5.263157895 21 GO:0009987 cellular process 1.30E-04 114 83 1.84E-13 399 267 14 5.243445693 47 GO:0050793 regulation of developmental process 5.88E-05 24 19 5.57E-11 111 78 4 5.128205128 11 GO:0048666 neuron development 2.57E-04 20 15 9.94E-17 124 98 5 5.102040816 21 GO:0044249 cellular biosynthetic process 6.99E-04 44 33 2.86E-04 114 79 4 5.063291139 4 GO:0060284 regulation of cell development 5.94E-05 13 9 2.99E-08 22 20 1 5 21 GO:0006928 movement of cell or subcellular component 4.00E-04 18 14 1.50E-07 50 40 2 5 44 GO:0009888 tissue development 8.70E-06 13 8 2.46E-06 29 20 1 5 21 GO:0009058 biosynthetic process 5.66E-04 46 35 3.54E-04 117 81 4 4.938271605 3 GO:1902578 single-organism localization 5.49E-04 49 28 9.53E-07 211 122 6 4.918032787 21 GO:0050794 regulation of cellular process 8.23E-08 70 51 1.66E-14 213 144 7 4.861111111 47 GO:0040011 locomotion 2.73E-07 43 34 5.94E-13 214 146 7 4.794520548 3 GO:2000026 regulation of multicellular organismal development 2.70E-05 26 18 1.24E-09 81 63 3 4.761904762 11 GO:0045944 positive regulation of transcription from RNA polymerase II promoter 3.36E-04 15 11 8.86E-11 59 42 2 4.761904762 11 GO:0007417 central nervous system development 2.74E-04 15 11 7.14E-04 21 21 1 4.761904762 18 GO:0030029 actin filament-based process 1.55E-04 31 22 8.14E-04 37 21 1 4.761904762 21 GO:0042330 taxis 7.15E-05 12 10 3.51E-07 26 21 1 4.761904762 21 GO:0006935 chemotaxis 2.30E-05 12 10 3.72E-07 25 21 1 4.761904762 11 GO:0031175 neuron projection development 1.90E-04 18 14 3.06E-14 111 86 4 4.651162791 21 GO:0044763 single-organism cellular process 1.44E-04 85 65 6.93E-10 317 220 10 4.545454545 27 GO:0050794 regulation of cellular process 2.31E-06 53 38 3.00E-05 34 22 1 4.545454545 47 GO:0005886 plasma membrane 3.39E-05 22 15 2.35E-14 103 66 3 4.545454545 22 GO:0023052 signaling 7.24E-05 32 27 1.01E-16 303 222 10 4.504504505 22 GO:0007154 cell communication 4.05E-05 33 28 7.67E-17 307 224 10 4.464285714 14 GO:0030036 actin cytoskeleton organization 4.46E-05 21 14 1.85E-04 29 23 1 4.347826087 21 GO:0045165 cell fate commitment 3.57E-04 11 7 3.47E-09 30 23 1 4.347826087 21 GO:0031175 neuron projection development 9.24E-05 13 10 2.25E-05 29 23 1 4.347826087 47 GO:0048731 system development 1.99E-04 37 29 1.10E-07 167 117 5 4.273504274 21 GO:0009888 tissue development 1.30E-05 27 20 9.51E-08 31 24 1 4.166666667 14 GO:0030029 actin filament-based process 1.57E-05 23 15 2.89E-05 32 25 1 4 47 GO:0001071 nucleic acid binding transcription factor activity 1.75E-06 14 10 1.32E-08 78 50 2 4 47 GO:0003700 sequence-specific DNA binding transcription factor activity 1.66E-06 14 10 1.32E-08 78 50 2 4 11 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity 4.33E-04 9 6 1.98E-09 38 26 1 3.846153846 21 GO:0048666 neuron development 1.67E-04 14 10 6.61E-06 32 26 1 3.846153846 16 GO:0003677 DNA binding 1.23E-04 13 11 1.77E-07 123 79 3 3.797468354 47 GO:0051239 regulation of multicellular organismal process 3.18E-04 23 17 4.05E-09 113 79 3 3.797468354 11 GO:0022603 regulation of anatomical structure morphogenesis 2.60E-07 18 12 2.91E-05 34 27 1 3.703703704 47 GO:0050789 regulation of biological process 2.35E-05 71 55 2.28E-28 402 276 10 3.623188406 16 GO:0006355 "regulation of transcription, DNA-templated" 3.34E-06 16 13 3.41E-11 128 83 3 3.614457831 16 GO:1903506 regulation of nucleic acid-templated transcription 3.34E-06 16 13 3.41E-11 128 83 3 3.614457831 16 GO:0006351 "transcription, DNA-templated" 1.16E-05 17 13 1.14E-09 128 83 3 3.614457831 16 GO:0097659 nucleic acid-templated transcription 1.16E-05 17 13 1.66E-09 128 83 3 3.614457831 16 GO:2001141 regulation of RNA biosynthetic process 4.94E-06 16 13 2.36E-11 129 84 3 3.571428571 16 GO:0032774 RNA biosynthetic process 1.54E-05 17 13 1.82E-09 129 84 3 3.571428571 27 GO:0050789 regulation of biological process 1.59E-04 67 45 4.62E-06 41 28 1 3.571428571 47 GO:0006935 chemotaxis 1.54E-06 12 10 3.55E-08 34 28 1 3.571428571 47 GO:0042330 taxis 5.14E-06 12 10 5.49E-08 35 28 1 3.571428571 16 GO:0051252 regulation of RNA metabolic process 1.10E-05 16 13 7.24E-12 132 86 3 3.488372093 47 GO:0065007 biological regulation 4.66E-05 72 56 4.25E-20 437 287 10 3.484320557 16 GO:0043565 sequence-specific DNA binding 9.16E-06 10 8 1.10E-10 87 58 2 3.448275862 16 GO:2000112 regulation of cellular macromolecule biosynthetic process 1.62E-05 16 13 3.02E-11 137 88 3 3.409090909 16 GO:0019219 regulation of nucleobase-containing compound metabolic process 6.70E-06 17 14 7.01E-12 136 89 3 3.370786517 16 GO:0010556 regulation of macromolecule biosynthetic process 2.43E-05 16 13 2.58E-11 138 89 3 3.370786517 16 GO:0051171 regulation of nitrogen compound metabolic process 9.79E-06 17 14 2.68E-12 138 90 3 3.333333333 16 GO:0001071 nucleic acid binding transcription factor activity 3.62E-06 10 9 3.68E-10 90 60 2 3.333333333 16 GO:0003700 sequence-specific DNA binding transcription factor activity 2.61E-05 9 8 3.68E-10 90 60 2 3.333333333 21 GO:0030182 neuron differentiation 1.62E-04 16 11 7.73E-07 37 30 1 3.333333333 16 GO:0031326 regulation of cellular biosynthetic process 3.01E-05 16 13 4.31E-12 141 91 3 3.296703297 16 GO:0009889 regulation of biosynthetic process 3.23E-05 16 13 6.58E-12 141 91 3 3.296703297 16 GO:0034654 nucleobase-containing compound biosynthetic process 9.34E-06 19 13 1.13E-08 141 93 3 3.225806452 16 GO:0018130 heterocycle biosynthetic process 1.62E-05 19 13 1.22E-07 141 93 3 3.225806452 21 GO:0009605 response to external stimulus 9.12E-05 17 13 2.60E-06 39 31 1 3.225806452 21 GO:0048523 negative regulation of cellular process 1.84E-04 25 18 4.87E-06 48 31 1 3.225806452 27 GO:0065007 biological regulation 2.87E-04 68 46 2.05E-05 45 31 1 3.225806452 16 GO:0019438 aromatic compound biosynthetic process 1.47E-05 19 13 3.47E-08 142 94 3 3.191489362 16 GO:1901362 organic cyclic compound biosynthetic process 2.54E-05 19 13 1.48E-07 143 94 3 3.191489362 16 GO:0044271 cellular nitrogen compound biosynthetic process 1.99E-05 19 13 3.68E-08 144 95 3 3.157894737 21 GO:0048699 generation of neurons 4.07E-05 18 13 2.23E-07 40 33 1 3.03030303 21 GO:0022008 neurogenesis 2.79E-04 18 13 8.42E-07 40 33 1 3.03030303 16 GO:0010468 regulation of gene expression 1.30E-04 16 13 2.88E-11 156 100 3 3 47 GO:0050794 regulation of cellular process 1.34E-07 57 46 1.19E-26 339 235 7 2.978723404 47 GO:0009653 anatomical structure morphogenesis 7.02E-06 38 31 2.23E-09 154 105 3 2.857142857 47 GO:0044763 single-organism cellular process 1.51E-04 68 52 1.37E-12 474 317 9 2.839116719 21 GO:0048869 cellular developmental process 5.30E-04 32 22 3.56E-08 102 74 2 2.702702703 16 GO:0019222 regulation of metabolic process 4.63E-06 23 17 8.72E-19 226 149 4 2.684563758 47 GO:0044700 single organism signaling 1.14E-06 36 29 3.66E-16 209 152 4 2.631578947 47 GO:0023052 signaling 5.88E-07 37 30 3.89E-16 209 152 4 2.631578947 47 GO:0007154 cell communication 8.99E-07 37 30 4.86E-16 211 153 4 2.614379085 16 GO:0031323 regulation of cellular metabolic process 1.41E-05 20 15 1.06E-14 178 115 3 2.608695652 47 GO:0010556 regulation of macromolecule biosynthetic process 5.61E-05 23 16 6.79E-10 121 77 2 2.597402597 21 GO:0007399 nervous system development 1.61E-04 22 15 4.51E-08 47 39 1 2.564102564 47 GO:0031326 regulation of cellular biosynthetic process 2.06E-04 22 15 1.12E-10 124 79 2 2.53164557 47 GO:0009889 regulation of biosynthetic process 8.01E-05 23 16 1.61E-10 124 79 2 2.53164557 47 GO:0009893 positive regulation of metabolic process 2.55E-04 17 11 3.23E-08 56 42 1 2.380952381 47 GO:0009605 response to external stimulus 6.14E-07 18 12 1.00E-07 56 42 1 2.380952381 47 GO:0032989 cellular component morphogenesis 2.72E-04 14 13 2.27E-06 62 44 1 2.272727273 47 GO:0043565 sequence-specific DNA binding 1.28E-04 12 9 1.55E-07 71 46 1 2.173913043 47 GO:0050896 response to stimulus 4.67E-05 45 34 1.27E-12 258 187 4 2.139037433 16 GO:0050794 regulation of cellular process 5.19E-06 33 23 1.30E-25 371 251 5 1.992031873 47 GO:0048523 negative regulation of cellular process 1.76E-04 21 15 4.53E-10 77 52 1 1.923076923 47 GO:0006928 movement of cell or subcellular component 3.23E-06 19 14 6.17E-11 76 60 1 1.666666667 16 GO:0050789 regulation of biological process 2.94E-05 42 28 2.05E-30 451 305 5 1.639344262 47 GO:0042221 response to chemical 2.97E-04 21 17 2.12E-04 89 61 1 1.639344262 16 GO:0065007 biological regulation 8.28E-05 42 28 1.58E-20 488 319 5 1.567398119 47 GO:0007166 cell surface receptor signaling pathway 2.46E-06 21 17 1.32E-10 86 65 1 1.538461538 47 GO:0007165 signal transduction 1.22E-06 33 26 4.10E-14 193 141 2 1.418439716 47 GO:0051716 cellular response to stimulus 1.79E-04 33 26 1.62E-11 204 150 2 1.333333333 4 GO:0007417 central nervous system development 1.51E-04 16 12 6.43E-04 12 10 0 0 4 GO:0008134 transcription factor binding 4.97E-04 13 9 8.02E-04 17 13 0 0 4 GO:0034765 regulation of ion transmembrane transport 1.59E-05 6 3 1.24E-03 9 5 0 0 4 GO:0034762 regulation of transmembrane transport 1.59E-05 6 3 1.24E-03 9 5 0 0 4 GO:0007420 brain development 1.70E-04 13 9 1.49E-03 10 8 0 0 5 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 7.56E-05 5 2 3.04E-05 8 6 0 0 5 GO:0098609 cell-cell adhesion 7.56E-05 5 2 3.04E-05 8 6 0 0 11 GO:0001745 compound eye morphogenesis 3.04E-04 7 4 3.01E-04 9 9 0 0 11 GO:0048749 compound eye development 6.43E-04 7 4 3.83E-04 10 10 0 0 18 GO:0008078 mesodermal cell migration 3.67E-06 8 6 5.81E-05 6 4 0 0 18 GO:0016199 axon midline choice point recognition 8.57E-04 4 4 3.00E-04 3 3 0 0 18 GO:0016198 axon choice point recognition 8.57E-04 4 4 3.00E-04 3 3 0 0 18 GO:0001764 neuron migration 1.08E-04 12 9 6.14E-04 8 7 0 0 18 GO:0008037 cell recognition 2.08E-05 10 10 6.88E-04 18 10 0 0 18 GO:0008038 neuron recognition 6.50E-05 9 9 1.11E-03 17 9 0 0 21 GO:0007389 pattern specification process 2.66E-04 11 8 1.64E-07 22 16 0 0 21 GO:0007411 axon guidance 1.01E-04 9 7 6.63E-07 20 16 0 0 21 GO:0048667 cell morphogenesis involved in neuron differentiation 5.39E-05 12 9 6.88E-07 23 18 0 0 21 GO:0097485 neuron projection guidance 1.79E-05 10 8 7.52E-07 20 16 0 0 21 GO:0007409 axonogenesis 7.42E-05 11 8 9.82E-07 22 17 0 0 21 GO:0048812 neuron projection morphogenesis 5.39E-05 12 9 1.06E-06 23 18 0 0 21 GO:0000904 cell morphogenesis involved in differentiation 7.58E-05 13 9 2.63E-06 23 18 0 0 21 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity 2.27E-04 7 6 4.01E-06 14 9 0 0 21 GO:0048858 cell projection morphogenesis 2.90E-04 12 9 1.60E-05 24 19 0 0 21 GO:0032990 cell part morphogenesis 3.63E-04 12 9 2.55E-05 24 19 0 0 21 GO:0044877 macromolecular complex binding 1.49E-04 12 7 2.67E-05 21 17 0 0 21 GO:0000902 cell morphogenesis 4.57E-05 16 12 4.83E-05 26 21 0 0 21 GO:0008356 asymmetric cell division 6.87E-04 4 2 9.83E-05 8 4 0 0 21 GO:0061564 axon development 1.41E-04 11 8 1.54E-04 24 18 0 0 21 GO:2000113 negative regulation of cellular macromolecule biosynthetic process 1.26E-05 13 9 2.27E-04 17 9 0 0 21 GO:0010558 negative regulation of macromolecule biosynthetic process 1.42E-05 13 9 2.27E-04 17 9 0 0 21 GO:0044212 transcription regulatory region DNA binding 1.16E-04 8 6 2.53E-04 12 10 0 0 21 GO:0031327 negative regulation of cellular biosynthetic process 1.51E-05 13 9 2.67E-04 17 9 0 0 21 GO:0000975 regulatory region DNA binding 1.38E-04 8 6 2.84E-04 12 10 0 0 21 GO:0001067 regulatory region nucleic acid binding 1.38E-04 8 6 2.84E-04 12 10 0 0 21 GO:0009890 negative regulation of biosynthetic process 1.71E-05 13 9 3.13E-04 17 9 0 0 21 GO:0031324 negative regulation of cellular metabolic process 4.42E-04 14 9 3.46E-04 26 14 0 0 21 GO:1902679 negative regulation of RNA biosynthetic process 1.62E-06 13 9 4.02E-04 14 8 0 0 21 GO:1903507 negative regulation of nucleic acid-templated transcription 1.50E-06 13 9 4.02E-04 14 8 0 0 21 GO:0045892 "negative regulation of transcription, DNA-templated" 1.50E-06 13 9 4.02E-04 14 8 0 0 21 GO:0000976 transcription regulatory region sequence-specific DNA binding 2.29E-04 6 4 4.48E-04 10 8 0 0 21 GO:0032989 cellular component morphogenesis 1.19E-05 19 13 4.55E-04 39 24 0 0 21 GO:0000122 negative regulation of transcription from RNA polymerase II promoter 4.97E-05 9 6 4.85E-04 12 6 0 0 21 GO:0051253 negative regulation of RNA metabolic process 2.58E-06 13 9 5.73E-04 14 8 0 0 21 GO:0051172 negative regulation of nitrogen compound metabolic process 1.18E-05 13 9 1.17E-03 15 9 0 0 21 GO:0022603 regulation of anatomical structure morphogenesis 5.45E-04 9 8 1.56E-03 11 9 0 0 27 GO:0001071 nucleic acid binding transcription factor activity 2.14E-07 15 12 4.27E-05 13 11 0 0 27 GO:0003700 sequence-specific DNA binding transcription factor activity 2.02E-07 15 12 4.27E-05 13 11 0 0 31 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity 3.33E-06 17 12 9.31E-09 27 17 0 0 31 GO:0001764 neuron migration 7.96E-06 12 8 3.24E-05 12 12 0 0 31 GO:0001763 morphogenesis of a branching structure 9.49E-04 9 5 8.19E-05 7 6 0 0 31 GO:0043009 chordate embryonic development 1.44E-03 14 8 8.43E-05 11 8 0 0 31 GO:0048754 branching morphogenesis of an epithelial tube 9.91E-04 8 5 2.54E-04 5 5 0 0 31 GO:0061138 morphogenesis of a branching epithelium 4.96E-04 9 5 4.49E-04 6 5 0 0 31 GO:0060562 epithelial tube morphogenesis 7.54E-05 19 10 1.45E-03 10 8 0 0 31 GO:0001745 compound eye morphogenesis 1.40E-03 9 4 2.19E-03 6 6 0 0 31 GO:0019904 protein domain specific binding 1.79E-03 15 10 2.35E-03 16 13 0 0 44 GO:0007389 pattern specification process 2.26E-06 8 5 2.13E-04 17 10 0 0 47 GO:0048667 cell morphogenesis involved in neuron differentiation 1.20E-04 10 9 1.21E-10 36 28 0 0 47 GO:0048812 neuron projection morphogenesis 1.20E-04 10 9 2.47E-10 36 28 0 0 47 GO:0009888 tissue development 1.06E-05 23 17 1.16E-09 44 32 0 0 47 GO:0007409 axonogenesis 3.94E-05 10 9 1.67E-09 33 25 0 0 47 GO:0007411 axon guidance 1.29E-05 9 8 3.74E-09 29 24 0 0 47 GO:0097485 neuron projection guidance 1.39E-05 9 8 4.52E-09 29 24 0 0 47 GO:0048666 neuron development 1.81E-04 12 9 1.44E-08 49 36 0 0 47 GO:0031175 neuron projection development 1.41E-04 11 9 1.95E-08 46 33 0 0 47 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity 4.41E-05 7 4 6.16E-08 20 14 0 0 47 GO:0060429 epithelium development 2.29E-05 20 14 6.65E-08 30 19 0 0 47 GO:0061564 axon development 1.27E-05 11 9 5.90E-07 38 25 0 0 47 GO:0010604 positive regulation of macromolecule metabolic process 3.18E-04 15 9 8.12E-06 36 27 0 0 47 GO:0044212 transcription regulatory region DNA binding 1.45E-04 7 4 2.76E-05 17 12 0 0 47 GO:0000975 regulatory region DNA binding 1.68E-04 7 4 3.24E-05 17 12 0 0 47 GO:0001067 regulatory region nucleic acid binding 1.68E-04 7 4 3.24E-05 17 12 0 0