Gingipains from the periodontal pathogen Porphyromonas gingivalis play a significant role in regulation of Angiopoietin 1 and Angiopoietin 2 in human aortic smooth muscle cells

Supplemental material

• Supplemental file 1 -

  Fig. S1. Release of gingipain from different strains of P. gingivalis. Fig. S2. Leupeptin inhibits P. gingivalis regulation of Angpt1, Angpt2, and ETS1 in AoSMCs. Fig. S3. F. alocis regulates Angpt1, Angpt2, and ETS1 gene expression in AoSMCs. Fig. S4. P. gingivalis and TNF regulation of Angpt2 in AoSMCs after 24 h. Fig. S5. LPS is not involved in P. gingivalis-mediated regulation of Angpt1 and Angpt2 production in AoSMCs.

  PDF, 439K