,author,study.id,pubyear,Mixed,Comparator,factor.journal.both,factor.citation.both,duration,group.all,group.t2dm,group.nodm,group.method,reporting.method,group.duration,factor.weeks.both,impute.wt.sd,pc.fat.control,age.rx,age.control,age.final.rx,age.final.control,pcmale.rx,pcmale.control,bmi.rx,bmi.control,Enrolled.n.rx,Enrolled.n.control,Complete.n.rx,Complete.n.control,factor.weight.rx,factor.bmi.rx,factor.cholesterol.rx,factor.hdl.rx,factor.ldl.rx,factor.tg.rx,factor.bpsystolic.rx,factor.weight.control,factor.bmi.control,factor.cholesterol.control,factor.hdl.control,factor.ldl.control,factor.tg.control,factor.bpsystolic.control,factor.duration.both,factor.numberenrolled.both,factor.numbercompleted.both,factor.t2dm.both,factor.age.both,factor.pcmen.both,factor.pcdm.both,factor.bpsystolic.both,factor.cholesterol.both,factor.hdl.both,factor.ldl.both,factor.tg.both,factor.bmi.both,factor.weight.both,factor.calories.rx,factor.calories.control,factor.calories.delta,factor.carb.rx,factor.protein.rx,factor.fat.rx,factor.carb.control,factor.protein.control,factor.fat.control,factor.carb.delta,factor.protein.delta,factor.fat.delta,outcome.mean.cholesterol.control,outcome.sd.cholesterol.control,outcome.pop.cholesterol.control,outcome.mean.cholesterol.rx,outcome.sd.cholesterol.rx,outcome.pop.cholesterol.rx,outcome.mean.hdl.control,outcome.sd.hdl.control,outcome.pop.hdl.control,outcome.mean.hdl.rx,outcome.sd.hdl.rx,outcome.pop.hdl.rx,outcome.mean.ldl.control,outcome.sd.ldl.control,outcome.pop.ldl.control,outcome.mean.ldl.rx,outcome.sd.ldl.rx,outcome.pop.ldl.rx,outcome.mean.tg.control,outcome.sd.tg.control,outcome.pop.tg.control,outcome.mean.tg.rx,outcome.sd.tg.rx,outcome.pop.tg.rx,outcome.mean.bmi.control,outcome.sd.bmi.control,outcome.pop.bmi.control,outcome.mean.bmi.rx,outcome.sd.bmi.rx,outcome.pop.bmi.rx,outcome.mean.weight.control,outcome.sd.weight.control,outcome.pop.weight.control,outcome.mean.weight.rx,outcome.sd.weight.rx,outcome.pop.weight.rx,outcome.mean.systolicbp.control,outcome.sd.systolicbp.control,outcome.pop.systolicbp.control,outcome.mean.systolicbp.rx,outcome.sd.systolicbp.rx,outcome.pop.systolicbp.rx 1,Bradley,Bradley,2009,No,Low Fat 20%,Diabetes,58:2741-48,8 wks,y,n,y,1,Completer,1,8,1,20.00%,37.1,40.5,37.3,40.7,42%,33%,34.5,32.8,14,13,12,12,97.7,34.5,179.5,56.8,95.4,140.6,122,91.5,32.8,193.1,54.1,110,136.9,127,8,27,24,None,39,38%,0%,124,187,56,103,139.7,34.5,94.6,1888,1697,191,94.4,94.4,125.9,254.6,84.9,37.7,-160.2,9.5,88.2,-34,24.8,12,-23.2,28.1,12,-9.7,9.3,12,-4.6,11.4,12,-17,22.7,12,-13.9,25.2,12,-10.6,40.8,12,-60.2,52.1,12,-2.3,2,12,-2.6,1.9,12,-6.5,6.4,12,-7.4,6.2,12,-8,13.7,12,-8,13.7,12 2,Brehm,Brehm.2003,2003,No,AHA,J Clin Endoc Met,88:1617-23,6 mo,y,n,y,1,Both,2,24,0,28.00%,44.2,43.1,44.7,43.6,0%,0%,33.2,34,26,27,22,20,91.2,33.2,206.3,51.8,124.9,148.7,116,92.3,34,184.4,48.8,113.8,109.3,115,24,53,42,None,43.7,0%,0%,115,195,50,119,128,33.6,91.7,1158,1257,-99,43.4,81.1,73.3,170,56.6,39.1,-126.6,24.5,34.2,-1.6,24.8,20,-0.9,28.1,22,4.1,9.3,20,7,11.4,22,-6,22.7,20,-0.8,25.2,22,1.8,40.8,20,-34.9,52.1,22,-1.5,2,20,-3.2,1.9,22,-3.9,1,20,-8.5,1,22,-2,13.7,20,-2,13.7,22 3,Brehm,Brehm.2005,2005,No,Low Fat,J Clin Endoc Met,90:1475-82,4 mo,y,n,y,1,Completer,1,16,0,29.00%,44.8,41.4,45.1,41.7,0%,0%,32.8,33.5,25,25,20,20,90.6,32.8,205,44.4,134.8,128.8,119,90.9,33.5,196.2,44.2,125.3,145.6,119,16,50,40,None,43.1,0%,0%,119,200.6,44.3,130.1,137.2,33.2,90.8,1288,1339,-51,48.3,90.2,81.6,177.4,60.3,43.1,-129.1,29.9,38.5,-7.36,24.8,20,-5.35,28.1,20,1.99,9.3,20,7.25,11.4,20,-8.68,22.7,20,-2.95,25.2,20,-14.98,40.8,20,-48.1,52.1,20,-2.4,2,20,-3.4,1.9,20,-6.14,4.07,20,-9.79,3.18,20,-3,13.7,20,-9,13.7,20 4,Brinkworth,Brinkworth2,2009,No,LowFat 26%,Am J Clin Nutr,90:23-32,1 yr,y,n,y,1,Completer,3,52,0,27.00%,40.9,40.8,41.9,41.8,26%,25%,31.9,31.5,61,57,33,36,93.9,33.6,208.5,56,123.6,147.7,132.7,94.9,33.3,212.4,52.5,131.3,159.2,135.2,52,118,69,None,51.4,25%,0%,132,223.4,46.3,142.1,134.4,31.7,89.2,1567,1505,62,19.8,133.7,101.9,167.9,85.8,45.1,-148.1,47.9,56.8,3.9,4,36,27,8,33,2.7,2,36,11.6,3,33,4,4,36,23.2,8,33,-19.5,4,36,-51.4,4,3,-4.1,0.4,36,-5.2,0.6,32,-11.5,1.2,36,-14.5,1.7,32,-14.6,2,36,-13.8,2.5,33 5,Dansinger,Dansinger,2005,No,Ornish Fat,JAMA,293(1):43-53,1 year,y,n,y,1,Both,3,52,1,17.10%,47,49,48,50,47%,57%,35,35,40,40,21,20,100,35,214,48,136,152,129,103,35,214,45,136,174,133,52,80,41,None,48,52%,0%,131,214,46,136,163,35,101.5,1705,1393,312,68,109,95.5,229,66,26.5,-161,43,69,-21.5,26,20,-8.1,31,21,-1.1,9.3,20,6.4,8.8,21,-25.2,20,20,-13.5,32,21,11,53,20,-2,117,21,-2.3,3.2,20,-1.4,2.1,21,-6.6,9.3,20,-3.9,6,21,0.9,11,20,0.3,17,21 6,de Luis,de Luis,2012,No,LowFat 27%,Diab Met Research & Reviews,28:663-8,3 mo,y,n,y,1,No drop outs,1,12,0,25.10%,43.5,43.5,43.7,43.7,26%,26%,35.5,35.7,147,158,147,158,94.9,35.8,200.3,51.5,123.9,126.1,138.8,92.2,35.6,203.1,56.9,125.2,114.2,144.5,12,305,305,None,43.5,26%,0%,142,200.4,54.3,123.5,119.7,35.6,93.3,1571,1614,-43,120,NA,NA,NA,NA,45,NA,NA,NA,-8.7,24.8,158,-9.2,28.1,147,-1.5,9.3,158,0.3,11.4,147,-4.9,22.7,158,-4.9,25.2,147,-4.4,40.8,158,-10.2,52.1,147,-1.6,2,158,-1.2,1.9,147,-4.1,6.4,158,-3.4,6.2,147,-10.2,13.7,158,-8.5,13.7,147 7,Flechter-Mors,Flechter-Mors,2010,No,LowFat 30%,Diab Metab Research & Reviews,26:393-405,1 yr,y,n,y,1,Completer,3,52,0,29.40%,49.3,50.2,50.3,51.2,22%,18%,36.2,36.3,55,55,31,49,100.2,36.2,211.2,50.2,145.4,178.6,NA,100.5,36.3,209.3,48.6,143.6,195.3,NA,52,110,74,None,49.7,20%,0%,NA,210,49.4,144,187.6,36.2,100.3,1319,1253,66,114,110.9,41,155,53.8,41,-41,57.1,0,-4.6,23.2,43,-5,30.9,31,0.4,3.9,43,2.3,8.5,31,-3.9,22.7,43,-1.9,25.2,31,-10.6,34.7,43,-62,30.1,31,-2.5,2,43,-4.3,1.9,31,-6.9,6.4,43,-11.8,6.8,31,NA,NA,NA,NA,NA,NA 8,Foster,Foster.2003,2003,No,LEARN,NEJM,348(21):2082-90,1 yr,y,n,y,1,Both,3,52,0,25.00%,44.1,44.1,45.1,45.1,36%,27%,33.9,34.4,33,30,20,17,98.7,33.9,200.5,46.8,129.5,121,120.5,98.3,34.4,193.7,49.4,119.8,122.5,123.3,52,63,37,None,44.1,32%,0%,121.9,197.1,48.1,124.6,126.8,34.1,98.5,NA,NA,NA,20,NA,NA,NA,NA,NA,NA,NA,NA,-10.7,10.4,17,0.2,12.7,20,1.5,15.2,17,8.5,22.4,20,-6.9,16.1,17,0.6,21.2,20,1.7,52.5,17,-35.6,23.6,20,-1.5,2,17,-2.5,1.9,20,-4.5,7.9,17,-7.3,7.3,20,3.6,15.8,17,-1.9,12.2,20 9,Foster,Foster.2010,2010,No,Standard LowFat,Ann Int Med,153(3):147-57,2 yr,y,n,y,2,ITT - LOCF,3,104,0,30.00%,46.2,44.9,48.2,46.9,33%,32%,36.1,36.1,153,154,88,86,103.3,36.1,188.6,46.2,120.2,113.3,124.3,103.5,36.1,192.4,45.4,124,124,124.6,104,307,174,None,45.5,32%,0%,124.5,190.5,45.8,122.1,118.7,36.1,103.4,NA,NA,NA,20,NA,NA,NA,NA,NA,NA,NA,NA,-2.8,24.8,105,-5.2,28.1,89,4.6,7.6,105,7.8,8.4,89,-8,17.7,105,-4.8,21.1,89,-14.6,58.5,105,-12.2,51.5,89,-2.6,2,105,-2.2,1.9,89,-7.4,9.1,105,-6.3,8.2,89,-2.6,12.9,105,-2.7,11.6,89 10,Gardner,Gardner,2007,No,Ornish Fat,JAMA,297(9):969-77,1 yr,y,n,y,2,ITT - LOCF,3,52,0,21.10%,42,42,43,43,0%,0%,32,32,77,76,68,59,86,32,187,53,109,125,118,86,32,184.6,50,111,118,116,52,153,127,None,42,0%,0%,117,186,52,110,122,32,86,1381,1408,-27,61.1,95.6,83.9,222.1,59.5,33,-161,36.1,50.9,-6.8,24.8,59,-0.2,28.1,68,0,6.3,59,4.9,9.1,68,-3.8,19,59,0.8,22.6,68,-14.9,46.2,59,-29.3,59,68,-0.77,2.14,59,-1.65,2.54,68,-2.2,5.8,59,-4.7,5.8,68,-1.9,7.7,59,-7.6,11,68 11,Lean,Lean,1997,No,LowFat 20%,Eur J Clin Nutr,51:243-8,6 mo,y,n,y,2,ITT - LOCF,2,26,0,20.50%,50.1,51.1,50.6,51.6,0%,0%,32.8,32.3,53,57,43,48,84.8,32.8,256.8,57.1,172.2,130.1,135.7,83.9,32.3,256,55.2,172.6,131.7,136.7,26,110,91,None,51,0%,0%,136,256,56,173,130.5,32.5,84.3,1197,1198,-1,110,89.4,46.5,185.6,62,27.3,-75.6,27.4,19.2,-13.1,26.8,40,-4.6,35.3,37,-0.8,1.8,37,1.9,9.8,34,-6.6,20.4,37,-1.2,30.4,34,-23.9,21.5,39,-22.2,22.1,34,-2.2,1.8,42,-2.6,2.1,40,-5.6,5,42,-6.8,5.2,40,-1.1,17.2,38,-0.3,17.9,36 12,Lim,Lim,2010,No,VeryLowFat,Nutr Metab Cardiovasc Dis 2010; ,20: 599_607,15 mo,y,n,y,2,ITT - Impute,3,64,0,12.50%,48.3,48.6,49.5,49.8,20%,20%,32.3,30.5,30,30,17,18,87.6,32.3,227.8,50.2,119.7,159.2,129.8,89.4,30.5,220.1,54.1,104.2,141.5,129.4,64,60,35,None,48.4,20%,0%,129.6,224,52.1,112,150.2,31.4,88.5,1835,1667,168,56.9,139.9,110.7,275.1,84.6,23.2,-218.2,55.3,87.5,-11.6,30.9,18,-15.4,30.9,17,3.9,11.6,18,3.9,11.6,17,-11.6,27,18,-11.6,27,17,8.9,34.7,18,-17.7,27,17,-0.7,2,18,-1.1,1.9,17,-2.1,4.7,18,-2.9,4.9,17,-6,13.3,18,-10.6,10.6,17 13,Meckling,Meckling,2004,No,Low Fat,J Clin Endoc Metab,89(6):2717-23,10 weeks,y,n,y,1,Completer,1,10,1,17.90%,41.2,43.2,41.4,43.4,33%,25%,32.2,32.2,15,16,15,16,91,32.2,230,49,169,136,124.8,92.3,32.2,228,52,165,134,121.3,10,31,31,None,42.2,29%,0%,123,229,51,167,135,32.2,91.7,1529,1447,82,59,100.6,94.6,225,70.9,28.8,-166,29.7,65.8,-63,26.1,15,2,28.1,16,-8,7.9,15,6,11.4,16,-52,22.7,15,1,25.2,16,-34,40.8,15,-42,52.1,16,-2.2,2,15,-2.1,1.9,16,-6.8,6.4,15,-7,6.2,16,-11.2,13.7,15,-10.2,13.7,16 14,Ruth,Ruth,2013,No,Low Fat,Metabolism,62:1779-87,12 wks,y,n,y,1,Completer,1,12,0,25.10%,43.5,41.5,43.7,41.7,10%,12%,37.1,35.9,29,26,18,15,100.5,37.1,185.8,50.9,110.7,121.2,122.3,99.3,35.9,178.3,52.4,107.9,90,117.2,12,55,43,None,42.5,11%,0%,119.7,182,51.6,109.3,105.6,36.5,99.9,1532,1439,93,39.4,125.6,95.5,201.8,76.6,40.1,-162.4,49,55.4,-10.2,24.2,15,-2.67,37.4,18,-5,10.5,15,5.1,7.3,18,-7.6,19.2,15,-1.1,36.1,18,11.3,35.3,15,-33.2,37.3,18,-1.8,1.5,15,-2.5,1.5,18,-5.26,4.67,15,-7.14,4.62,18,2.5,12.4,15,-8.8,14.1,18 15,Truby,Truby-LoFAT,2006,No,Low Fat,Br Med J,332(7553):1309-14,6 mo,y,n,y,2,ITT - LOCF,2,24,1,26.00%,40.9,40.6,41.4,41.1,26%,28%,31.9,31.6,57,58,40,41,90.3,31.9,222.8,47.1,143.6,145.9,135,89.8,31.5,217.4,47.1,138.6,140.6,130,24,115,41,None,40.6,27%,0%,132,220,47.1,140.9,143.4,31.7,90,1627,1534,93,49.6,110.7,105.9,202.1,74.3,44.8,-152.5,36.4,61.1,-19.3,19.3,61,-11.2,30.9,57,-7.7,15.1,61,-3.1,15.2,57,-17,34,61,-6.2,35.6,57,-15.9,37.8,61,-56.7,29.9,57,-3.1,2,61,-3.1,1.9,57,-8.8,6.4,61,-8.9,6.2,57,-4.5,9.8,61,-7.2,11.6,57 17,Volek,Volek,2009,No,LowFat 25%,Lipids,44:297-309,12 wk,y,n,y,1,No drop outs,1,12,1,24.40%,32.6,36.9,32.8,37.1,50%,50%,33.5,32.1,20,20,20,20,96.5,33.5,208,36,130,211,NA,94.4,32.1,204,39,128,187,NA,12,40,40,None,34.8,50%,0%,NA,206,37,129,199,32.8,95.4,1504,1478,26,44.8,104.8,100.2,208.3,71.5,40,-163.5,33.3,60.2,-9,24.8,20,-1,28.1,20,-1,9.3,20,4,11.4,20,-2,22.7,20,5,25.2,20,-36,40.8,20,-107,52.1,20,-1.8,2,20,-3.5,1.9,20,-5.2,6.4,20,-10.2,6.2,20,NA,NA,NA,NA,NA,NA 18,Yancy,Yancy,2004,No,LowFat,Ann Int Med,140:769-77,6 mo,y,n,y,2,ITT - Impute,2,26,0,29.30%,44.2,45.6,44.7,46.1,25%,22%,34.6,34,60,60,45,34,97.8,34.6,244.5,55.4,157.2,157.8,130.3,96.8,34,239.9,54.1,148,190.8,130.3,24,120,79,None,44.9,23%,0%,NA,234,54.4,152.6,76.1,34.3,97.3,1461,1502,-41,29.5,97.9,110.6,197.6,70.5,48.9,-168.1,27.4,61.7,-13.7,24.8,45,-8.1,28.1,34,-1.6,9.3,45,5.5,11.4,34,-7.4,22.7,45,1.6,25.2,34,-27.9,40.8,45,-74.2,52.1,34,-2.3,2,45,-4.3,1.9,34,-6.5,7.5,45,-12,7.1,34,-7.5,16.2,45,-9.6,14.6,34