Dynamics of Mycobacteriophage-Mycobacterial Host Interaction: Evidence for Secondary Mechanisms for Host Lethality

Supplemental material

  • Supplemental file 1 -

    Theoretical and experimental estimations of the fraction of cells expected to be infected at a given MOI (Fig. S1), fidelity of the FACS-based cell-counting procedure (Fig. S2), simultaneous monitoring of cell death and phage growth (Fig. S3), deriving rate constants for bacterial and phage growth (Fig. S4), mathematical modeling of host-phage interactions (Fig. S5), effect of Mn2+ on phage growth (Fig. S6), FACSAria system calculations (Table S1), and evaluation of theoretical/experimental parameters (Table S2).

    PDF, 906K