A Branch Point of Streptomyces Sulfur Amino Acid Metabolism Controls the Production of Albomycin

Supplemental material

  • Supplemental file 1 -

    Comparison of key sulfur amino acid metabolism genes (Table S1), semi-log plot of zone of inhibition diameter versus amount of pure ABM (Fig. S1), HPLC quantification curve of pure ABM (Fig. S2), UV-Vis absorption spectra (Fig. S3), bioassay plates (Fig. S4), comparison of NBRC 13350 whole genome and ATCC 700974 draft genome (Fig. S5), PCR analysis of the construction of mutants (Fig. S6), HPLC-fluorescence detection (Fig. S7), and the proposed AbmD reaction that forms the -C-S-C- group of ABM (Fig. S8).

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