Three-Dimensional Structural Characterization of HIV-1 Tethered to Human Cells

Supplemental material

• Supplemental file 1 -

  Movie S1 (Cryo-ET of HIV-1 VLPs tethered to an HT1080 cell, corresponding to Fig. 1E.)

  MOV, 18M

• Supplemental file 2 -

  Movie S2 (Cryo-ET of HIV virions tethered to an HT1080 cell, corresponding to Fig. 3C).

  MOV, 18M

• Supplemental file 3 -

  Movie S3 (Cryo-ET of released HIV-1.)

  MOV, 6.5M

• Supplemental file 4 -

  Fig. S1 (Illustration of the extended and parallel tetherin models.)

  Fig. S2 (Tetherin restriction phenotyping, subcellular localization, and comparative expression levels in HT1080 and HeLa cells.)

  Fig. S3 (Dynamic tetherin model illustrating arrangement and orientation of tetherin homodimers at sites of HIV-1 assembly and budding.)

  Supplmental Movie Legends.

  PDF, 4.1M