Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes

Supplemental material

• Supplemental file 1 -

  Fig. S1. MaR1 enhances macrophage intracellular ROS generation with P. gingivalis and A. actinomycetemcomitans. Fig. S2. Representative images of the bacterial cultures following incubation of macrophages from HC and LAP patients with vehicle (PBS^+/+, 37°C, pH = 7.4) or MaR1 (1 nM). Fig. S3. MaR1 enhances neutrophil intracellular ROS generation for P. gingivalis and A. actinomycetemcomitans. Fig. S4. MaR1 enhances macrophage phagocytosis of F. nucleatum. Fig. S5. Maresin 1 levels were reduced after pathogen incubations.

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