Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses Is Toxic to Caenorhabditis elegans

Supporting Information for Cheesman et al., 2016

Files in this Data Supplement:

• Figure S1 - The nasy-1(ums8) gain-of-function allele causes the induction of p38 MAPK dependent putative immune effectors in a manner that is synergistic with R24. (.eps, 6,560 KB)
• Figure S2 - RNAI-mediated knockdown of pmk-1 suppresses F08G5.6::GFP activation and the delayed development of the nsy-1(ums8) mutant. (.eps, 19,816 KB)
• Figure S3 - nsy-1(ums8) gain-of-function animals are resistant to killing by P. aeruginosa. (.eps, 744 KB)
• Figure S4 - XBP-1 is required for development in the presence of the immunostimulatory xenobiotic R24. (.eps, 1,465 KB)
• Table S1 - Relative Expression of the 118 Genes in the nanoString nCounter Gene Expression Analysis. (.xlsx, 21 KB)