Table S2. Gene Ontology (GO) annotation associated with biological processes in H2O2 + B12 (B12) treatment compared with H2O2 alone (Ctrl) treatment.,,,
GO-ID,Biologicla Processes,p values,Genes
44260,cellular macromolecule metabolic process,1.30E-37,U2AF2 INTS1 INTS2 INTS3 AURKB CD2AP SART1 BTK CUL3 INTS9 NONO CUL2 EPC1 APP EPC2 CUL5 ISG15 INTS5 INTS6 MAP3K8 FAU H2AFX LSM2 PTBP2 EIF2B2 CUL1 EMG1 RAN PTBP1 ST13 MAPK1 PPP1CA RPS19 RPS16 FUS RAD23A NFKBIB HSPA1A HSPA1B CALR TK1 HNRNPA3 RPS27 FBXO6 PRPF40A MDFI DHX9 YEATS4 RPSA MLL CREBBP YTHDC1 EPRS SMAD2 RPS6 DDX5 HNRNPA1 HNRNPA0 RPS7 SRSF5 RPL18A UBA1 UBA2 CHAF1A ABCF1 ELF3 COPS5 PDIA6 QARS NFKB1 DMAP1 CANX WBP4 YBX1 CCNE2 HSF1 HSF2 EEF2K QKI BRD8 ATF7IP CDC6 CTBP1 LYN HERC6 TP53 HERC5 HERC3 RBBP7 SMN2 SMN1 SENP2 HNRPDL TAF10 PFDN1 PSEN1 RIPK1 RAB5A RUVBL2 CAND1 RUVBL1 USP25 POLR2H PML RPL27A RPL36 ABI2 FKBP1A RPL38 SF3B4 POT1 POLR2A SUMO3 SUMO2 SUMO1 GPHN SET MDC1 CD2BP2 HSP90AB4P PPP2CA AGO1 ACTL6A THBS1 TRIP13 AIMP1 AIMP2 TRIM28 ELAVL1 PPP1R10 SOD1 SF3A2 PSMD12 FYN PPP1R8 SFPQ DPM1 DPM2 DPM3 APBB1 BARD1 MORF4L1 RALY THRA CHERP MORF4L2 SAE1 DSE TOP1 SRRM1 PRKACA RPN2 RBM10 INSR RPS27A SATB1 SNRPN STK24 MAGOH EFTUD2 RELA HNRNPA2B1 HNRNPR HNRNPU RSL1D1 PSMA2 PA2G4 HIF1A EP300 ARRB2 PSMA3 DSP SNRPA CSTA NFE2L2 RNF20 UBA52 KALRN MEAF6 BLM FGR STRAP GRB2 PNPT1 MAPKAPK3 NEDD8 TRRAP PSMA7 SRC HNRNPL PSMB4 HNRNPM HNRNPK PTK6 RPL8 HNRNPD HNRNPC TRAF6 IVL EIF3M FN1 PTPN6 ITK P4HB EPAS1 SSB INTS10 KAT5 RBMX BRCA1 POLD3 HDAC5 IKBKE CDKN1A VCP PLK1 PRKAR1B GTF2F1 TDG CIRBP HSPD1 USPL1 CTCF RPS3 MEN1 FOS CASP3 PRMT1 PCBP3 GTF2A1 PCBP1 PCBP2 CASP8 RANBP2 KHDRBS1 PRKCA PPP2R1A CDK1 KHDRBS3 HSP90AA1 SARS CYCS ESR1 UBE2I PRKCE CDK2 UBE2N EIF4G1 DDR1 EVPL UBE2K HIPK2 LCK UCHL5 MDM2 BUB1B UBD KPNA2 PPP2R2A FRK UBE3A STUB1 DIMT1 MAP3K3 NUDT21 YES1 DUS3L TERF1 CEBPA PTPRC HCK CBL PARK2 SIRT7 FBL DIS3 HSP90B1 APAF1 JAK3 TBL1X
9987,cellular process,6.68E-37,LDHB TUBB2A INTS1 INTS2 RORB INTS3 ITSN2 RORA ITSN1 SART1 BTK ACTG1 CUL3 MAGED1 INTS9 CUL2 EPC1 APP HTR1B EPC2 CUL5 INTS5 SERPINE2 ISG15 HIST1H2BI INTS6 MAP3K8 FAU LSM2 FAS PTBP2 CUL1 KIF5B EMG1 NCF1 RCOR1 PTBP1 BCL2L10 ST13 NME4 JUP MAPK1 NME2 PPP1CA RPS19 NME3 RPS16 HNF4A NME1 JUN GRAP2 SH3GL1 RAD23A NFKBIB NFKBIA HSPA1A BCL2L1 HSPA1B VPS72 RPS27 NPHP1 PRPF40A SSSCA1 DHX9 YEATS4 RPSA RPS6 GAS7 RPS7 GH1 SRSF5 RGS2 PKP1 PKP2 UBA1 RAPSN UBA2 PKP3 PKP4 RTN4 ELF3 PDIA6 QARS YBX1 CCNE2 BNIPL HSF1 HSF2 EEF2K QKI MYC BRD8 ARHGEF4 ATF7IP CDC6 SH3PXD2A NDUFB10 ACTA1 LYN LYZ TP53 CFTR ARHGEF9 SMN2 SMN1 CIAO1 TAF10 NCK2 PFDN1 HIST2H2BE NCK1 RIPK1 RUVBL2 CAND1 RUVBL1 USP25 ARL4D PML RPL36 ABI2 AZIN1 RPL38 FEM1B SF3B4 POT1 AMPH GPHN SORBS1 PPP2CA RASA1 TRIP13 SHMT1 ACTC1 HIST1H2BC HIST1H2BD AIMP1 HIST1H2BE AIMP2 HIST1H2BF HIST1H2BG TRIM28 CSNK2B LMNA ELAVL1 PPP1R10 ACLY STAB2 SF3A2 PLSCR1 SFPQ DPM1 DPM2 DPM3 DNM1 BARD1 RALY CHERP XPO5 RBM7 VCL PACSIN1 DAB2 PACSIN2 RPN2 INSR RPS27A STK24 RELA RBL1 RELB HNRNPA2B1 ACTN1 ACTN2 FADD HNRNPR IRS1 HNRNPU PA2G4 EP300 HIF1A ARRB2 NFE2L2 SMARCA2 UBA52 MEAF6 FGR MAPKAPK3 ANLN KCNA5 HNRNPL HNRNPM VDR DOCK2 ISYNA1 TUBB HNRNPK PTK6 RPL8 HNRNPD HNRNPC TRAF6 EPAS1 MYO1C FDPS VAV2 VAV1 RBMX POLD3 HDAC5 IKBKE CDKN1A TNFSF11 ATF3 VCP PLK1 PRKAR1B GTF2F1 TDG HSPD1 USPL1 CTCF SKAP2 RPS3 CASP3 PRMT1 DES CASP4 GTF2A1 CASP9 CASP7 CASP8 DLG4 RHOB NDUFS3 CASP2 DLG1 SEC23A PPP2R1A CDK1 SARS CYCS ESR1 NCL CDK2 LCK CNTN2 UCHL5 UBD PPP2R2A VIM STUB1 CDH5 DIMT1 VCAM1 ANXA7 COL17A1 ATIC HSPA4 TERF1 CEBPA HCK CBL MRGBP COL5A2 FBL COL5A1 HSP90B1 DSC1 APAF1 JAK3 SNX30 TBL1X APIP DHFRP1 U2AF2 AURKB CD2AP RAB1A NONO INSIG2 H2AFV H2AFZ H2AFX EIF2B2 RAN KRT19 KRT18 KRT14 PIAS1 FUS TALDO1 AKAP13 DMWD CALR PXN CDC37 TK1 HNRNPA3 FBXO6 IDH1 EMD HIP1 HNRNPAB MDFI BMP1 MLL TP53BP2 CREBBP YTHDC1 EPRS SMAD2 DDX5 HNRNPA1 HNRNPA0 DLX2 NOTCH1 NR1I2 RPL18A CHAF1A ABCF1 RAB5B COPS5 MYO7A GJA1 NFKB1 DMAP1 CANX WBP4 ASGR1 TRIAP1 MBTD1 NOS2 DYNC1H1 COL11A1 TUBB3 CTBP1 HERC6 HERC5 HERC3 RBBP7 SENP2 HNRPDL PSEN1 RAB5A TOMM20 SH3KBP1 AVEN SRCAP BCAT1 POLR2H YWHAZ RPL27A NCF1B FKBP1A HPRT1 POLR2A SUMO3 SUMO2 SUMO1 CBR1 SET CD2BP2 MDC1 HSP90AB4P BCL11A AGO1 ACTL6A THBS1 BAIAP2L1 ILF3 SOD1 STAT3 GBA3 TJP1 PSMD12 PPP1R8 FYN SVIL APBB1 PAICS MORF4L1 THRA CCDC85B MORF4L2 CRABP2 SAE1 VTN DSE CBX6 TOP1 SRRM1 PRKACA PPP4C RBM10 SATB1 SNRPN MAGOH EFTUD2 ARNTL RSL1D1 PSMA2 PYCR1 TNS3 PSMA3 DSP SNRPA CSTA SEPT7 RNF20 KALRN CAV3 SNX9 GRAP BLM STRAP GRB2 PNPT1 NEDD8 SOX6 TRRAP PSMA7 SRC PSMB4 NPM1 IVL EIF3M FN1 MAFG PTPN6 ITK GABARAPL2 P4HB AK2 SSB ITGA4 INTS10 KAT5 BRCA1 PLCG1 PLCG2 CIRBP MEN1 FOS PCBP3 PCBP1 PCBP2 NCKIPSD RANBP2 TUBA1A KPNB1 KHDRBS1 SHBG PRKCA SOX10 KHDRBS3 HSP90AA1 SP100 MPP6 UBE2I PRKCE NLRP1 UBE2N EIF4G1 DDR1 CRKL EVPL UBE2K ITGB1BP1 HIPK2 MDM2 BUB1B KPNA2 SMARCAD1 FRK KRT6A XIAP UBE3A NDUFB9 NDUFB1 KRT5 MAP3K3 CENPA SAFB NUDT21 KRT8 PSTPIP1 ENO3 SCG5 PIK3R3 YES1 ING1 PIK3R1 DUS3L APC ACTB PTPRC NDUFA5 NUP153 PARK2 SIRT7 DIS3 SH3BP4 GPI NME1-NME2 PECAM1 PPP1R13B CRK
43170,macromolecule metabolic process,1.54E-34,U2AF2 INTS1 INTS2 INTS3 AURKB CD2AP SART1 BTK CUL3 INTS9 NONO CUL2 EPC1 APP EPC2 CUL5 ISG15 INTS5 INTS6 MAP3K8 FAU H2AFX LSM2 PTBP2 EIF2B2 CUL1 EMG1 RAN PTBP1 ST13 MAPK1 PPP1CA RPS19 RPS16 FUS RAD23A NFKBIB HSPA1A HSPA1B CALR TK1 HNRNPA3 RPS27 FBXO6 PRPF40A MDFI DHX9 YEATS4 RPSA BMP1 MLL CREBBP YTHDC1 EPRS SMAD2 RPS6 DDX5 HNRNPA1 HNRNPA0 RPS7 SRSF5 RPL18A UBA1 UBA2 CHAF1A ABCF1 ELF3 COPS5 PDIA6 QARS NFKB1 DMAP1 CANX WBP4 YBX1 CCNE2 HSF1 HSF2 EEF2K QKI DPP9 BRD8 ATF7IP CDC6 CTBP1 LYN HERC6 HERC5 LYZ TP53 HERC3 RBBP7 SMN2 SMN1 HNRPDL SENP2 SENP3 TAF10 PFDN1 PSEN1 RIPK1 RAB5A RUVBL2 CAND1 RUVBL1 USP25 POLR2H SHFM1 RPL27A PML RPL36 ABI2 FKBP1A RPL38 SF3B4 POT1 POLR2A SUMO3 SUMO2 SUMO1 GPHN SET MDC1 CD2BP2 HSP90AB4P PPP2CA AGO1 ACTL6A THBS1 TRIP13 AIMP1 AIMP2 TRIM28 ELAVL1 PPP1R10 SOD1 SF3A2 PSMD12 FYN PPP1R8 SFPQ DPM1 DPM2 DPM3 APBB1 BARD1 MORF4L1 RALY THRA CHERP MORF4L2 SAE1 DSE TOP1 SRRM1 PRKACA RPN2 RBM10 INSR RPS27A SATB1 SNRPN STK24 MAGOH EFTUD2 RELA HNRNPA2B1 HNRNPR HNRNPU RSL1D1 PSMA2 PA2G4 HIF1A EP300 ARRB2 PSMA3 DSP SNRPA CSTA NFE2L2 RNF20 UBA52 KALRN MEAF6 BLM FGR STRAP GRB2 PNPT1 MAPKAPK3 NEDD8 TRRAP PSMA7 SRC HNRNPL PSMB4 HNRNPM HNRNPK PTK6 RPL8 HNRNPD HNRNPC TRAF6 IVL EIF3M FN1 PTPN6 ITK P4HB EPAS1 SSB INTS10 KAT5 RBMX BRCA1 POLD3 HDAC5 IKBKE CDKN1A VCP PLK1 PRKAR1B GTF2F1 TDG CIRBP HSPD1 USPL1 CTCF RPS3 MEN1 FOS CASP6 CASP3 PRMT1 CASP4 PCBP3 GTF2A1 CASP9 PCBP1 CASP7 PCBP2 CASP8 RANBP2 CASP2 KHDRBS1 PRKCA PPP2R1A CDK1 KHDRBS3 HSP90AA1 SARS CYCS ESR1 UBE2I PRKCE NCL CDK2 UBE2N EIF4G1 DDR1 EVPL UBE2K HIPK2 LCK UCHL5 MDM2 BUB1B UBD KPNA2 PPP2R2A FRK UBE3A STUB1 DIMT1 MAP3K3 ZNF708 NUDT21 KRT1 SCG5 YES1 DUS3L APC TERF1 CEBPA PTPRC HCK CBL KLK5 PARK2 SIRT7 FBL COL5A1 DIS3 CASP10 HSP90B1 APAF1 JAK3 TBL1X
44237,cellular metabolic process,1.70E-28,LDHB U2AF2 INTS1 INTS2 RORA INTS3 AURKB CD2AP SART1 BTK CUL3 INTS9 NONO CUL2 EPC1 CUL5 EPC2 APP ISG15 INTS5 INTS6 MAP3K8 FAU H2AFX LSM2 FAS PTBP2 EIF2B2 CUL1 NCF1 EMG1 RAN PTBP1 NME4 ST13 MAPK1 PPP1CA NME2 NME3 RPS19 HNF4A RPS16 NME1 FUS TALDO1 RAD23A NFKBIB HSPA1A HSPA1B CALR PXN TK1 HNRNPA3 RPS27 FBXO6 IDH1 PRPF40A MDFI DHX9 YEATS4 RPSA MLL CREBBP EPRS YTHDC1 SMAD2 DDX5 RPS6 HNRNPA1 HNRNPA0 RPS7 SRSF5 NR1I2 RPL18A UBA1 UBA2 CHAF1A ABCF1 COPS5 ELF3 PDIA6 NFKB1 QARS DMAP1 WBP4 CANX YBX1 CCNE2 HSF1 HSF2 EEF2K QKI NOS2 BRD8 ATF7IP CDC6 CTBP1 NDUFB10 LYN HERC6 HERC5 TP53 HERC3 RBBP7 SMN2 SMN1 HNRPDL SENP2 CIAO1 TAF10 PFDN1 PSEN1 RIPK1 RAB5A RUVBL2 CAND1 RUVBL1 USP25 POLR2H BCAT1 RPL27A PML NCF1B RPL36 ABI2 FKBP1A AZIN1 RPL38 HPRT1 SF3B4 POT1 POLR2A SUMO3 SUMO2 CBR1 SUMO1 GPHN SET MDC1 CD2BP2 HSP90AB4P PPP2CA AGO1 ACTL6A THBS1 TRIP13 SHMT1 AIMP1 AIMP2 TRIM28 ELAVL1 PPP1R10 ACLY SOD1 SF3A2 GBA3 PSMD12 FYN PPP1R8 SFPQ DPM1 DPM2 DPM3 PAICS APBB1 BARD1 MORF4L1 RALY THRA CHERP MORF4L2 CRABP2 SAE1 DSE TOP1 SRRM1 PRKACA RPN2 RBM10 INSR RPS27A SATB1 SNRPN STK24 MAGOH EFTUD2 RELA HNRNPA2B1 HNRNPR HNRNPU RSL1D1 PSMA2 PYCR1 PA2G4 HIF1A EP300 ARRB2 PSMA3 DSP SNRPA CSTA NFE2L2 RNF20 UBA52 KALRN CAV3 MEAF6 BLM FGR STRAP GRB2 PNPT1 MAPKAPK3 NEDD8 TRRAP PSMA7 SRC HNRNPL PSMB4 VDR HNRNPM ISYNA1 HNRNPK PTK6 RPL8 HNRNPD HNRNPC TRAF6 IVL EIF3M FN1 PTPN6 ITK GABARAPL2 P4HB EPAS1 FDPS AK2 SSB INTS10 KAT5 RBMX BRCA1 POLD3 HDAC5 IKBKE CDKN1A ATF3 PLCG1 VCP PLK1 PRKAR1B GTF2F1 PLCG2 TDG CIRBP HSPD1 USPL1 CTCF RPS3 MEN1 FOS CASP3 PRMT1 PCBP3 GTF2A1 PCBP1 PCBP2 CASP8 RANBP2 NDUFS3 KHDRBS1 PRKCA PPP2R1A CDK1 KHDRBS3 HSP90AA1 SARS CYCS ESR1 UBE2I PRKCE CDK2 UBE2N EIF4G1 DDR1 EVPL UBE2K HIPK2 LCK UCHL5 MDM2 BUB1B UBD KPNA2 PPP2R2A SMARCAD1 FRK UBE3A NDUFB9 STUB1 NDUFB1 DIMT1 MAP3K3 ATIC NUDT21 ENO3 YES1 PIK3R1 DUS3L TERF1 CEBPA PTPRC NDUFA5 HCK CBL PARK2 SIRT7 FBL DIS3 GPI HSP90B1 NME1-NME2 APAF1 JAK3 TBL1X APIP DHFRP1
44238,primary metabolic process,9.30E-28,LDHB U2AF2 INTS1 INTS2 RORA INTS3 AURKB CD2AP SART1 BTK CUL3 INTS9 NONO CUL2 ACBD3 EPC1 CUL5 EPC2 APP ISG15 INTS5 INSIG2 INTS6 MAP3K8 FAU H2AFX LSM2 FAS PTBP2 EIF2B2 CUL1 EMG1 RAN PTBP1 NME4 ST13 MAPK1 PPP1CA NME2 NME3 RPS19 HNF4A RPS16 NME1 FUS TALDO1 RAD23A NFKBIB HSPA1A HSPA1B CALR TK1 HNRNPA3 RPS27 FBXO6 IDH1 PRPF40A MDFI DHX9 YEATS4 RPSA MLL BMP1 CREBBP EPRS YTHDC1 SMAD2 DDX5 RPS6 HNRNPA1 HNRNPA0 RPS7 SRSF5 NR1I2 RPL18A UBA1 UBA2 CHAF1A ABCF1 COPS5 ELF3 PDIA6 NFKB1 QARS DMAP1 WBP4 CANX YBX1 CCNE2 HSF1 HSF2 EEF2K QKI NOS2 DPP9 BRD8 ATF7IP CDC6 CTBP1 LYN HERC6 HERC5 TP53 HERC3 CFTR RBBP7 SMN2 SMN1 HNRPDL SENP2 SENP3 TAF10 PFDN1 PSEN1 RIPK1 RUVBL2 CAND1 RUVBL1 USP25 POLR2H BCAT1 GANAB SHFM1 RPL27A PML NCF1B RPL36 ABI2 FKBP1A AZIN1 RPL38 HPRT1 SF3B4 POT1 POLR2A SUMO3 SUMO2 SUMO1 GPHN SET MDC1 CD2BP2 HSP90AB4P PPP2CA AGO1 ACTL6A THBS1 TRIP13 SHMT1 AIMP1 AIMP2 TRIM28 ELAVL1 PPP1R10 ACLY SOD1 SF3A2 GBA3 PSMD12 FYN PPP1R8 SFPQ DPM1 DPM2 DPM3 PAICS APBB1 BARD1 MORF4L1 RALY THRA CHERP MORF4L2 CRABP2 SAE1 DSE TOP1 SRRM1 PRKACA RPN2 RBM10 INSR RPS27A SATB1 SNRPN STK24 MAGOH EFTUD2 RELA HNRNPA2B1 TECR HNRNPR HNRNPU RSL1D1 PSMA2 PYCR1 PA2G4 HIF1A EP300 ARRB2 PSMA3 DSP SNRPA CSTA NFE2L2 RNF20 UBA52 KALRN CAV3 MEAF6 BLM FGR STRAP PNPT1 MAPKAPK3 NEDD8 TRRAP PSMA7 SRC HNRNPL PSMB4 VDR HNRNPM ISYNA1 HNRNPK PTK6 RPL8 HNRNPD HNRNPC TRAF6 IVL EIF3M FN1 PTPN6 ITK P4HB EPAS1 FDPS AK2 SSB INTS10 KAT5 RBMX BRCA1 POLD3 HDAC5 IKBKE CDKN1A ATF3 PLCG1 VCP PLK1 PRKAR1B GTF2F1 PLCG2 TDG CIRBP HSPD1 USPL1 CTCF RPS3 MEN1 FOS CASP6 CASP3 PRMT1 CASP4 PCBP3 GTF2A1 CASP9 PCBP1 CASP7 PCBP2 CASP8 RANBP2 CASP2 KHDRBS1 PRKCA PPP2R1A CDK1 KHDRBS3 HSP90AA1 SARS CYCS ESR1 UBE2I PRKCE NCL CDK2 UBE2N EIF4G1 DDR1 EVPL UBE2K HIPK2 LCK UCHL5 MDM2 BUB1B UBD KPNA2 PPP2R2A SMARCAD1 FRK UBE3A STUB1 DIMT1 MAP3K3 ATIC ZNF708 NUDT21 KRT1 ENO3 SCG5 PAFAH1B2 YES1 PIK3R1 DUS3L APC TERF1 CEBPA PTPRC HCK CBL KLK5 PARK2 SIRT7 FBL DIS3 GPI CASP10 HSP90B1 NME1-NME2 AKR1B1 APAF1 JAK3 TBL1X APIP DHFRP1
90304,nucleic acid metabolic process,1.46E-27,MORF4L1 RALY THRA CHERP U2AF2 MORF4L2 INTS1 INTS2 INTS3 SART1 INTS9 NONO TOP1 EPC1 EPC2 APP INTS5 INTS6 SRRM1 H2AFX LSM2 PTBP2 RBM10 SNRPN EMG1 RAN MAGOH EFTUD2 PTBP1 HNRNPA2B1 HNRNPR HNRNPU RSL1D1 PA2G4 RPS19 HIF1A RPS16 ARRB2 SNRPA NFE2L2 FUS BLM STRAP RAD23A NFKBIB PNPT1 HSPA1A HSPA1B TK1 HNRNPL HNRNPA3 HNRNPM HNRNPK HNRNPD FBXO6 HNRNPC PRPF40A DHX9 MLL EPAS1 YTHDC1 EPRS SSB SMAD2 INTS10 KAT5 RPS6 DDX5 HNRNPA1 RBMX BRCA1 HNRNPA0 RPS7 POLD3 SRSF5 VCP GTF2F1 TDG CIRBP HSPD1 CHAF1A COPS5 ELF3 NFKB1 QARS CTCF DMAP1 WBP4 YBX1 MEN1 CCNE2 FOS CASP3 PCBP3 GTF2A1 HSF2 PCBP1 PCBP2 QKI KHDRBS1 ATF7IP CDC6 PPP2R1A KHDRBS3 SARS CYCS TP53 ESR1 RBBP7 SMN2 SMN1 CDK2 UBE2N EIF4G1 HNRPDL SENP2 TAF10 RUVBL2 RUVBL1 KPNA2 POLR2H SF3B4 POT1 POLR2A DIMT1 SUMO1 SET MDC1 CD2BP2 PPP2CA NUDT21 AGO1 DUS3L TRIP13 TERF1 CEBPA AIMP1 ELAVL1 PPP1R10 SIRT7 SOD1 SF3A2 FBL DIS3 PPP1R8 SFPQ APAF1 BARD1
6139,"nucleobase,nucleoside,nucleotide and nucleic acid metabolic process",8.22E-27,MORF4L1 RALY LDHB THRA CHERP U2AF2 MORF4L2 INTS1 INTS2 INTS3 RORA SART1 INTS9 NONO TOP1 EPC1 EPC2 APP INTS5 INTS6 SRRM1 H2AFX PTBP2 LSM2 RBM10 SNRPN RAN EMG1 MAGOH EFTUD2 PTBP1 HNRNPA2B1 HNRNPR HNRNPU RSL1D1 NME4 MAPK1 NME2 PA2G4 NME3 RPS19 HIF1A RPS16 ARRB2 NME1 SNRPA NFE2L2 FUS TALDO1 BLM STRAP NFKBIB RAD23A PNPT1 HSPA1A HSPA1B TK1 HNRNPA3 HNRNPL HNRNPM HNRNPK FBXO6 HNRNPD IDH1 HNRNPC PRPF40A DHX9 MLL EPAS1 AK2 EPRS YTHDC1 SSB SMAD2 INTS10 KAT5 DDX5 RPS6 HNRNPA1 RBMX BRCA1 HNRNPA0 RPS7 POLD3 SRSF5 VCP GTF2F1 TDG CIRBP HSPD1 CHAF1A COPS5 ELF3 NFKB1 QARS CTCF DMAP1 WBP4 YBX1 MEN1 CCNE2 FOS CASP3 PCBP3 GTF2A1 HSF2 PCBP1 PCBP2 QKI KHDRBS1 ATF7IP CDC6 PPP2R1A KHDRBS3 SARS CYCS TP53 ESR1 RBBP7 SMN2 SMN1 CDK2 UBE2N EIF4G1 HNRPDL SENP2 TAF10 RUVBL2 RUVBL1 KPNA2 SMARCAD1 POLR2H HPRT1 SF3B4 POT1 POLR2A DIMT1 SUMO1 SET MDC1 CD2BP2 ATIC PPP2CA NUDT21 AGO1 DUS3L TRIP13 TERF1 CEBPA SHMT1 AIMP1 PPP1R10 ELAVL1 ACLY SIRT7 SOD1 SF3A2 FBL DIS3 NME1-NME2 PPP1R8 SFPQ APAF1 PAICS DHFRP1 BARD1
16043,cellular component organization,4.48E-25,TUBB2A ITSN2 AURKB ITSN1 CD2AP SART1 CUL3 EPC1 APP EPC2 H2AFV HIST1H2BI H2AFZ H2AFX FAS KIF5B RAN RCOR1 JUP KRT19 NME1 JUN KRT14 PIAS1 SH3GL1 IQCB1 BCL2L1 CALR VPS72 PXN EMD NPHP1 HIP1 HNRNPAB SSSCA1 YEATS4 MLL CREBBP EPRS SMAD2 RPS6 GAS7 SRSF5 NOTCH1 CHAF1A ELF3 RAB5B MYO7A GJA1 QARS DMAP1 ASGR1 MBTD1 DYNC1H1 COL11A1 TUBB3 BRD8 CDC6 ACTA1 TP53 RBBP7 SMN2 SMN1 NCK2 TAF10 PSEN1 HIST2H2BE NCK1 RAB5A TOMM20 SH3KBP1 RUVBL2 RUVBL1 SRCAP POLR2H YWHAZ PML ABI2 FKBP1A HPRT1 POT1 AMPH POLR2A SET SORBS1 CD2BP2 ACTL6A THBS1 SHMT1 HIST1H2BC ACTC1 HIST1H2BD HIST1H2BE HIST1H2BF BAIAP2L1 HIST1H2BG TRIM28 CSNK2B LMNA STAB2 SF3A2 SOD1 PLSCR1 TJP1 SVIL APBB1 DNM1 MORF4L1 MORF4L2 VTN CBX6 VCL PACSIN1 DAB2 PACSIN2 PRKACA PPP4C INSR SATB1 RBL1 ACTN1 ACTN2 FADD IRS1 EP300 HIF1A ARRB2 DSP SMARCA2 RNF20 SEPT7 KALRN CAV3 MEAF6 BLM GRB2 ANLN KCNA5 TRRAP SOX6 SRC TUBB DOCK2 NPM1 FN1 EPAS1 VAV2 KAT5 VAV1 HDAC5 TNFSF11 VCP PLK1 GTF2F1 CIRBP HSPD1 CTCF SKAP2 MEN1 CASP3 DES GTF2A1 CASP7 CASP8 DLG4 NCKIPSD TUBA1A DLG1 SEC23A PRKCA PPP2R1A CDK1 HSP90AA1 CYCS MPP6 UBE2I NCL CDK2 UBE2N CNTN2 MDM2 UBD BUB1B SMARCAD1 UBE3A COL17A1 KRT5 CENPA SAFB KRT8 HSPA4 APC TERF1 ACTB CEBPA HCK PARK2 MRGBP COL5A2 COL5A1 SH3BP4 HSP90B1 PECAM1 APAF1 CRK
34641,cellular nitrogen compound metabolic process,5.78E-23,MORF4L1 RALY LDHB THRA CHERP U2AF2 MORF4L2 INTS1 INTS2 INTS3 RORA SART1 NONO INTS9 TOP1 EPC1 EPC2 APP INTS5 INTS6 SRRM1 H2AFX PTBP2 LSM2 RBM10 SNRPN RAN EMG1 MAGOH EFTUD2 PTBP1 HNRNPA2B1 HNRNPR HNRNPU RSL1D1 NME4 PYCR1 MAPK1 NME2 PA2G4 NME3 RPS19 HIF1A HNF4A RPS16 ARRB2 NME1 SNRPA NFE2L2 FUS TALDO1 BLM STRAP NFKBIB RAD23A PNPT1 HSPA1A HSPA1B TK1 HNRNPA3 HNRNPL HNRNPM HNRNPK FBXO6 HNRNPD IDH1 HNRNPC PRPF40A DHX9 MLL EPAS1 AK2 EPRS YTHDC1 SSB SMAD2 INTS10 KAT5 DDX5 RPS6 HNRNPA1 RBMX BRCA1 HNRNPA0 RPS7 POLD3 SRSF5 VCP GTF2F1 TDG CIRBP HSPD1 CHAF1A COPS5 ELF3 NFKB1 QARS CTCF DMAP1 WBP4 YBX1 MEN1 CCNE2 FOS CASP3 PCBP3 GTF2A1 HSF2 PCBP1 PCBP2 QKI NOS2 KHDRBS1 ATF7IP CDC6 PPP2R1A KHDRBS3 SARS CYCS TP53 ESR1 RBBP7 SMN2 SMN1 CDK2 UBE2N EIF4G1 HNRPDL SENP2 TAF10 RUVBL2 RUVBL1 KPNA2 SMARCAD1 POLR2H BCAT1 AZIN1 HPRT1 SF3B4 POT1 POLR2A DIMT1 SUMO1 GPHN SET MDC1 CD2BP2 ATIC PPP2CA NUDT21 AGO1 DUS3L TRIP13 TERF1 CEBPA SHMT1 AIMP1 PPP1R10 ELAVL1 ACLY PARK2 SIRT7 SOD1 SF3A2 FBL DIS3 NME1-NME2 PPP1R8 SFPQ APAF1 APIP PAICS DHFRP1 BARD1
8152,metabolic process,9.82E-23,LDHB U2AF2 INTS1 INTS2 RORA INTS3 AURKB CD2AP SART1 BTK NONO CUL3 INTS9 CUL2 ACBD3 EPC1 CUL5 EPC2 APP INSIG2 ISG15 INTS5 INTS6 MAP3K8 FAU H2AFX LSM2 FAS PTBP2 EIF2B2 CUL1 RAN NCF1 EMG1 PTBP1 NME4 ST13 MAPK1 PPP1CA NME2 NME3 RPS19 HNF4A RPS16 NME1 FUS TALDO1 RAD23A NFKBIB HSPA1A HSPA1B CALR PXN TK1 HNRNPA3 RPS27 FBXO6 IDH1 PRPF40A MDFI DHX9 YEATS4 RPSA MLL BMP1 CREBBP EPRS YTHDC1 SMAD2 DDX5 RPS6 HNRNPA1 HNRNPA0 RPS7 SRSF5 NR1I2 RPL18A UBA1 UBA2 CHAF1A ABCF1 COPS5 ELF3 PDIA6 NFKB1 QARS DMAP1 WBP4 CANX YBX1 CCNE2 HSF1 HSF2 EEF2K QKI NOS2 DPP9 BRD8 ATF7IP CDC6 CTBP1 NDUFB10 LYN HERC6 HERC5 LYZ TP53 HERC3 CFTR RBBP7 SMN2 SMN1 HNRPDL SENP2 CIAO1 SENP3 TAF10 PFDN1 PSEN1 RIPK1 RAB5A RUVBL2 CAND1 RUVBL1 USP25 POLR2H BCAT1 GANAB SHFM1 RPL27A PML NCF1B RPL36 ABI2 FKBP1A AZIN1 RPL38 HPRT1 SF3B4 POT1 POLR2A SUMO3 SUMO2 CBR1 SUMO1 GPHN SET MDC1 CD2BP2 HSP90AB4P PPP2CA AGO1 ACTL6A THBS1 TRIP13 SHMT1 AIMP1 AIMP2 TRIM28 ELAVL1 PPP1R10 ACLY SOD1 SF3A2 GBA3 PSMD12 FYN PPP1R8 SFPQ DPM1 DPM2 DPM3 PAICS APBB1 BARD1 MORF4L1 RALY THRA CHERP MORF4L2 CRABP2 SAE1 DSE TOP1 SRRM1 PRKACA RPN2 RBM10 INSR RPS27A SATB1 SNRPN STK24 MAGOH EFTUD2 RELA HNRNPA2B1 TECR HNRNPR HNRNPU RSL1D1 PSMA2 PYCR1 PA2G4 HIF1A EP300 ARRB2 PSMA3 DSP SNRPA CSTA NFE2L2 RNF20 UBA52 KALRN CAV3 MEAF6 BLM FGR STRAP GRB2 PNPT1 MAPKAPK3 NEDD8 TRRAP PSMA7 SRC HNRNPL PSMB4 VDR HNRNPM ISYNA1 HNRNPK PTK6 RPL8 HNRNPD HNRNPC TRAF6 IVL EIF3M FN1 PTPN6 ITK GABARAPL2 P4HB EPAS1 MYO1C FDPS AK2 SSB INTS10 KAT5 RBMX BRCA1 POLD3 HDAC5 IKBKE CDKN1A ATF3 PLCG1 VCP PLK1 PRKAR1B GTF2F1 PLCG2 TDG CIRBP HSPD1 USPL1 CTCF RPS3 MEN1 FOS CASP6 CASP3 PRMT1 CASP4 PCBP3 GTF2A1 CASP9 PCBP1 CASP7 PCBP2 CASP8 RANBP2 NDUFS3 CASP2 KHDRBS1 PRKCA PPP2R1A CDK1 KHDRBS3 HSP90AA1 SARS CYCS ESR1 UBE2I PRKCE NCL CDK2 UBE2N EIF4G1 DDR1 EVPL UBE2K HIPK2 LCK UCHL5 MDM2 BUB1B UBD KPNA2 PPP2R2A SMARCAD1 FRK UBE3A NDUFB9 STUB1 NDUFB1 DIMT1 MAP3K3 ATIC ZNF708 NUDT21 KRT1 ENO3 SCG5 PAFAH1B2 YES1 PIK3R1 DUS3L APC TERF1 CEBPA PTPRC NDUFA5 HCK CBL KLK5 PARK2 SIRT7 FBL COL5A1 DIS3 GPI CASP10 HSP90B1 NME1-NME2 AKR1B1 APAF1 JAK3 TBL1X APIP DHFRP1
48518,positive regulation of biological process,4.41E-22,THRA VTN RORB RORA ITSN1 SART1 BTK MAGED1 CUL3 EPC1 CUL2 CUL5 APP SERPINE2 PACSIN3 PRKACA H2AFX FAS RPN2 INSR CUL1 RAN RELA RELB FADD ARNTL IRS1 PSMA2 JUP TNS3 MAPK1 NME2 NME3 RPS19 HIF1A EP300 PIAS4 HNF4A ARRB2 NME1 JUN PSMA3 PIAS1 NFE2L2 RNF20 SMARCA2 KALRN CAV3 BLM AKAP13 NFKBIA SOX6 BCL2L1 PSMA7 CALR SRC PSMB4 VDR TUBB NPM1 TRAF6 EMD HNRNPAB HIP1 YEATS4 MLL BMP1 EPAS1 TP53BP2 CREBBP SMAD2 KAT5 DDX5 RPS6 VAV2 VAV1 BRCA1 HDAC5 DLX2 GH1 IKBKE NOTCH1 CDKN1A NR1I2 TNFSF11 ATF3 VCP PLK1 PLCG2 CIRBP HSPD1 RTN4 GJA1 NFKB1 CTCF RPS3 MEN1 FOS TRIAP1 BNIPL CASP6 CASP3 CASP4 HSF1 CASP8 RHOB NOS2 NDUFS3 MYC CASP2 PRKCA ATF7IP ARHGEF4 SOX10 PPP2R1A CDK1 HSP90AA1 SP100 LYN TP53 ESR1 CFTR ARHGEF9 PRKCE NLRP1 CDK2 UBE2N SENP2 CIAO1 NCK2 PSEN1 NCK1 RIPK1 HIPK2 LCK MDM2 UBD CAND1 SMARCAD1 KRT6A UBE3A PML FKBP1A HPRT1 FEM1B STUB1 POT1 SUMO3 VCAM1 SUMO2 SUMO1 MAP3K3 SORBS1 PPP2CA KRT1 THBS1 PIK3R1 RASA1 APC TERF1 CEBPA PTPRC KLK5 TRIM28 CBL ILF3 PARK2 SIRT7 SOD1 STAT3 CASP10 NME1-NME2 PSMD12 ILF2 FYN PPP1R13B TBL1X APBB1 BARD1
44419,interspecies interaction between organisms,4.78E-22,CUL2 TOP1 CUL5 ISG15 INSR KPNB1 CUL1 DLG1 ATF7IP SATB1 CTBP1 SP100 LYN RAN RELA RCOR1 RBL1 TP53 UBE2I FADD EIF4G1 MAPK1 KRT19 EP300 KRT18 JUN HIPK2 LCK PSMA3 MDM2 KPNA2 SRCAP UBE3A GRB2 RAD23A VIM PML NFKBIA NCF1B PSMA7 SRC VCAM1 PSMB4 HNRNPK CENPA KRT8 NPM1 PIK3R1 CEBPA HCK CREBBP FDPS KAT5 HNRNPA1 STAT3 PLCG1 FYN HSPD1
48522,positive regulation of cellular process ,1.20E-21,THRA VTN RORB RORA ITSN1 SART1 BTK MAGED1 CUL3 EPC1 CUL2 CUL5 APP PACSIN3 SERPINE2 PRKACA H2AFX FAS RPN2 INSR CUL1 RAN RELA FADD ARNTL IRS1 PSMA2 JUP TNS3 MAPK1 NME2 NME3 RPS19 HIF1A EP300 HNF4A ARRB2 PIAS4 NME1 JUN PSMA3 PIAS1 NFE2L2 RNF20 SMARCA2 KALRN CAV3 BLM AKAP13 NFKBIA SOX6 BCL2L1 PSMA7 CALR PSMB4 VDR TUBB NPM1 TRAF6 HNRNPAB HIP1 YEATS4 MLL EPAS1 TP53BP2 CREBBP SMAD2 KAT5 DDX5 RPS6 VAV2 VAV1 BRCA1 HDAC5 DLX2 GH1 IKBKE NOTCH1 CDKN1A NR1I2 TNFSF11 ATF3 VCP PLK1 CIRBP HSPD1 RTN4 GJA1 NFKB1 CTCF RPS3 MEN1 FOS TRIAP1 BNIPL CASP6 CASP3 CASP4 CASP8 NDUFS3 MYC CASP2 PRKCA ATF7IP ARHGEF4 SOX10 PPP2R1A CDK1 HSP90AA1 SP100 LYN TP53 ESR1 ARHGEF9 PRKCE NLRP1 CDK2 UBE2N SENP2 CIAO1 NCK2 PSEN1 NCK1 RIPK1 HIPK2 LCK MDM2 UBD CAND1 SMARCAD1 KRT6A UBE3A PML FKBP1A HPRT1 FEM1B STUB1 POT1 SUMO3 VCAM1 SUMO2 SUMO1 MAP3K3 SORBS1 PPP2CA THBS1 PIK3R1 APC TERF1 CEBPA PTPRC TRIM28 CBL KLK5 ILF3 PARK2 SIRT7 SOD1 STAT3 CASP10 NME1-NME2 PSMD12 ILF2 PPP1R13B TBL1X APBB1 BARD1
10467,gene expression,1.20E-21,RALY THRA CHERP U2AF2 INTS1 INTS2 INTS3 SART1 INTS9 NONO EPC1 APP INTS5 INTS6 SRRM1 FAU LSM2 PTBP2 RBM10 EIF2B2 RPS27A SNRPN EMG1 MAGOH EFTUD2 HNRNPA2B1 PTBP1 HNRNPR HNRNPU RSL1D1 PA2G4 RPS19 HIF1A RPS16 ARRB2 SNRPA NFE2L2 UBA52 FUS STRAP NFKBIB PNPT1 CALR HNRNPL HNRNPA3 HNRNPM RPS27 HNRNPK RPL8 HNRNPD HNRNPC EIF3M PRPF40A DHX9 RPSA MLL EPAS1 YTHDC1 EPRS SSB SMAD2 INTS10 RPS6 DDX5 RBMX HNRNPA1 HNRNPA0 RPS7 SRSF5 RPL18A GTF2F1 HSPD1 ABCF1 ELF3 COPS5 QARS NFKB1 WBP4 YBX1 RPS3 GTF2A1 HSF2 PCBP1 PCBP2 EEF2K QKI CASP2 KHDRBS1 PPP2R1A KHDRBS3 SARS TP53 ESR1 SMN2 SMN1 HNRPDL TAF10 PSEN1 POLR2H RPL27A RPL36 FKBP1A RPL38 SF3B4 STUB1 POLR2A DIMT1 CD2BP2 PPP2CA NUDT21 KRT1 SCG5 DUS3L TRIP13 CEBPA AIMP1 AIMP2 PPP1R10 SIRT7 SF3A2 FBL DIS3 PPP1R8 SFPQ
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