# # Supplementary Table 3. MIDAS formatted CSV file. # The file contains the stimulus, inhibition, time and expression values of the experimental data from Figure 3A suitable for # simulation with CellNetOptimizer (http://http://www.cellnopt.org/). # TR:mock:CellLine,TR:NGF,TR:MEKi,TR:JNKi,TR:PI3Ki,DA:Klf2,DA:Klf4,DA:Btg2,DA:Dusp6,DA:Maff,DA:Jund,DA:Fosl1,DA:Junb,DA:Klf5,DA:Klf6,DA:Myc,DA:Tieg1,DA:Cited2,DA:Zfp36,DA:Npy,DA:Mmp10,DV:Klf2,DV:Klf4,DV:Btg2,DV:Dusp6,DV:Maff,DV:Jund,DV:Fosl1,DV:Junb,DV:Klf5,DV:Klf6,DV:Myc,DV:Tieg1,DV:Cited2,DV:Zfp36,DV:Npy,DV:Mmp10 1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0 1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0 1,1,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0 1,1,0,0,1,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0 1,1,0,0,0,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,0.8444,0.6734,0.7466,0.3473,0.763,0.9821,0.823,0.8974,0.1225,0.8137,0.0642,0.3297,0.5304,0.7843,0.0203,0.4308 1,1,1,0,0,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,0.9364,0.6859,0.8121,0.8725,0.9218,0.9936,0.7838,0.8302,0.0404,0.8529,0.2105,0.797,0.107,0.3976,0.0122,0.001 1,1,0,1,0,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,0.7312,0.5198,0.5415,0.5303,0.7646,0.6453,0.4247,0.7863,0.0156,0.3422,0.0002,0.4495,0.0049,0.0288,0.0002,0.0078 1,1,0,0,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,0.5585,0.7861,0.6402,0.0757,0.8356,0.9822,0.8369,0.8048,0.0123,0.6018,0.1554,0.0486,0.287,0.6975,0.0025,0.5863 1,1,0,0,0,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,0.7399,0.8309,0.6293,0.8009,0.8717,0.9844,0.8877,0.8626,0.6915,0.8635,0.629,0.287,0.7578,0.6179,0.2681,0.7352 1,1,1,0,0,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,0.9288,0.7303,0.7763,0.8929,0.9622,0.977,0.8645,0.6577,0.2259,0.7856,0.3962,0.7584,0.0853,0.2613,0.0763,0.1047 1,1,0,1,0,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,0.173,0.2015,0.0704,0.6618,0.8344,0.9861,0.5368,0.3045,0.0404,0.092,0.0206,0.1187,0.0228,0.0675,0.0055,0.1403 1,1,0,0,1,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,0.1046,0.9141,0.4411,0.5529,0.8394,0.049,0.9153,0.8031,0.7255,0.8521,0.7598,0.012,0.703,0.4295,0.1254,0.8214 1,1,0,0,0,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,0.8065,0.7524,0.6125,0.842,0.9119,0.9956,0.9228,0.8863,0.8505,0.9082,0.5418,0.7787,0.6852,0.5191,0.5037,0.8474 1,1,1,0,0,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,0.8979,0.5956,0.5649,0.8934,0.9568,0.9399,0.8669,0.4939,0.1402,0.7571,0.3538,0.6279,0.0096,0.0081,0.173,0.3374 1,1,0,1,0,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,0.0091,0.3774,0.2848,0.5798,0.8682,0.9968,0.3423,0.0004,0.0034,0.0106,0.0849,0.4515,0.0692,0.1947,0.0635,0.5679 1,1,0,0,1,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,0.7391,0.6881,0.4504,0.7707,0.8901,0.9812,0.8928,0.8948,0.818,0.8712,0.598,0.6664,0.7477,0.6121,0.2951,0.8094 1,1,0,0,0,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,0.759,0.4897,0.0184,0.8818,0.9079,0.9952,0.897,0.8118,0.8038,0.8908,0.4404,0.2744,0.5361,0.4111,0.6228,0.8714 1,1,1,0,0,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,0.8648,0.4054,0.5099,0.8957,0.9538,0.9534,0.8622,0.3422,0.1332,0.7332,0.0754,0.3429,0.077,0.0564,0.2408,0.6902 1,1,0,1,0,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,0.4695,0.3319,0.3052,0.7342,0.901,0.9792,0.3772,0.2419,0.0072,0.6039,0.1574,0.2851,0.0006,0.0785,0.1992,0.4938 1,1,0,0,1,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,0.763,0.3532,0.0299,0.7328,0.6057,0.6,0.8978,0.7548,0.7021,0.8205,0.4661,0.0757,0.5797,0.2163,0.3814,0.8288 1,1,0,0,0,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,0.0913,0.0389,0.0034,0.7631,0.7837,0.4682,0.8374,0.6046,0.3835,0.6007,0.1623,0.1209,0.2278,0.02,0.569,0.8211 1,1,1,0,0,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,0.8664,0.4256,0.4859,0.8812,0.9555,0.9921,0.8224,0.2958,0.1709,0.4853,0.0035,0.3141,0.0907,0.0054,0.2422,0.579 1,1,0,1,0,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,0.3804,0.3184,0.2896,0.7555,0.9084,0.9952,0.4755,0.6219,0.023,0.5026,0.1209,0.3818,0.0033,0.3108,0.2046,0.422 1,1,0,0,1,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,0.5488,0.5,0.0013,0.7992,0.7917,0.872,0.874,0.8225,0.6238,0.8616,0.338,0.1261,0.5089,0.2346,0.4512,0.8602 1,1,0,0,0,12,12,12,12,12,12,12,12,12,12,12,12,12,12,12,12,0.6625,0.4954,0.1327,0.8279,0.9121,0.9159,0.8397,0.5658,0.5364,0.8017,0.3791,0.1764,0.1184,0.0009,0.665,0.857 1,1,1,0,0,12,12,12,12,12,12,12,12,12,12,12,12,12,12,12,12,0.8651,0.6095,0.5009,0.9067,0.9527,0.9858,0.8464,0.3109,0.2593,0.6999,0.0001,0.197,0.1137,0.0021,0.2631,0.6358 1,1,0,1,0,12,12,12,12,12,12,12,12,12,12,12,12,12,12,12,12,0.1138,0.0691,0.0885,0.7048,0.72,0.9943,0.2233,0.1198,0.0198,0.032,0.2175,0.0514,0.0579,0.0367,0.2,0.5183 1,1,0,0,1,12,12,12,12,12,12,12,12,12,12,12,12,12,12,12,12,0.8968,0.669,0.0777,0.8618,0.4978,0.9879,0.8759,0.8447,0.4042,0.8917,0.5401,0.308,0.4797,0.3081,0.5898,0.8063 1,1,0,0,0,24,24,24,24,24,24,24,24,24,24,24,24,24,24,24,24,0.2412,0.6218,0.0839,0.8344,0.8765,0.9917,0.813,0.7314,0.3344,0.7776,0.018,0.2297,0.0001,0.0898,0.8014,0.8919 1,1,1,0,0,24,24,24,24,24,24,24,24,24,24,24,24,24,24,24,24,0.6409,0.1826,0.107,0.9001,0.9257,0.9934,0.7671,0.0558,0.1048,0.1652,0.7065,0.0002,0.3395,0.427,0.5481,0.69 1,1,0,1,0,24,24,24,24,24,24,24,24,24,24,24,24,24,24,24,24,0.5069,0.5328,0.4733,0.7351,0.8485,0.9961,0.5309,0.5256,0.4624,0.6273,0.027,0.5417,0.0013,0.1496,0.3629,0.3392 1,1,0,0,1,24,24,24,24,24,24,24,24,24,24,24,24,24,24,24,24,0.8518,0.5781,0.0273,0.8609,0.7046,0.9887,0.7762,0.8121,0.4867,0.87,0.2067,0.2589,0.3002,0.1622,0.686,0.7473 1,1,0,0,0,48,48,48,48,48,48,48,48,48,48,48,48,48,48,48,48,0.3775,0.0692,0.0786,0.7658,0.5929,0.9625,0.678,0.4702,0.3171,0.5597,0.33,0.0164,0.0612,0.0096,0.8213,0.8423 1,1,1,0,0,48,48,48,48,48,48,48,48,48,48,48,48,48,48,48,48,0.2688,0.3706,0.1201,0.9021,0.8717,0.9866,0.602,0.0164,0.0287,0.4459,0.7928,0.1511,0.4133,0.1013,0.7099,0.7043 1,1,0,1,0,48,48,48,48,48,48,48,48,48,48,48,48,48,48,48,48,0.0003,0.2009,0.2531,0.6718,0.7976,0.9967,0.1102,0.3978,0.5667,0.2162,0.136,0.1709,0.0385,0.222,0.453,0.452 1,1,0,0,1,48,48,48,48,48,48,48,48,48,48,48,48,48,48,48,48,0.8891,0.0327,0.078,0.8581,0.1916,0.997,0.7435,0.884,0.411,0.8723,0.005,0.424,0.0911,0.1451,0.6889,0.7248