Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response

Supplemental Material for Hoffmann et al., 2016

Files in this Data Supplement:

  • Figure S1 - Selection of randomly created tti2 mutations that cause slow growth. (.pdf, 124 KB)
  • Figure S2 - GAL10-TTI2 expression in galactose and raffinose containing media. (.pdf, 100 KB)
  • Figure S3 - Relative levels of constitutive and depleted Tti2 expression. (.pdf, 104 KB)
  • Figure S4 - Depleting Tti2 does not result in aggregation of Mec1. (.pdf, 111 KB)
  • Figure S5 - Synthetic slow growth due to exon 1 of the human Huntingtin gene containing a 103 residue polyQ sequence. (.pdf, 90 KB)
  • Figure S6 - Overexpression of HSP26, HSP104 or HSPHSP42 does not compensate for depleting Tti2. (.pdf, 169 KB)
  • Table S1 - Strains used in this study. (.pdf, 263 KB)
  • Table S2 - Oligonucleotides used in this study. (.pdf, 117 KB)