S4: ClustalW alignment in FASTA format used to build the phylogenetic tree of the half ABC transporters using amino acid sequences from D. immitis, C. elegans, and B. malayi. The amino acid sequences of D. immitis were based on nucleotide translation to protein sequence. The accession numbers of the different sequences used are available in Table 1. ClusterW alignment has been performed with Geneious Pro.5.6.3 software using Matrix Blosum. ClusterW alignment was trimmed before position 260 and after position 868 of the alignment. The trimmed regions were not included in the subsequent phylogenetic analysis. >Cel-HAF-4 -------------------MNSTVASR---FSWGLILASIDFLACLLFACLHDGTFKFANFTSQFG--DFSFFTSTIDLF LLQFFRFALWMVPAAIHVAN---KADTLTMWKEPIFCSALLICAASPTKLLLLTEKL----KPDEFLTFGDTAFLVWN-- --------------FISAIILNSSWTRYFSRT-----------------------------PSSYIILEDEDLEVA---- ------------PKQTFELIFRLLQYCKREWLWHISGFSWLFIYSITRIFVPYYTGQVIATVVATKS------------- ------YPALSNAVYIMTIISLVSAVAAGFRGGSFEYAYARIQRAIRYDLFHGLVKQDVAFYDAHK--TGEVTSRLAADC QTMSDTVALNVNVFLRNCVMLLGSMIFMMKLS-WRLSLVTFILVPIIFVASKIFGTYYDLLSERTQDTIAESNDVAEEVL STMRTVRSFSCENVEADRFYGKLTHTLDVTRTKAIAYIGFLWVSELFQSFIIVS-VLWYGGHLVLTQKMKGDLLVSFLLY QMQLGDNLRQMGEVWTGLMQSVGASRKVFEYIDREPQIQHNG---EYMPENVVGKIEFRNVHFSYPTRSDQPILKDLSFT VEPGETVALVGPSGSGKSSCISLLENFYVPNAGQVLVDGVPLEEFEHHYIH-KKIALVGQEPVLFARSVMENVRYG---V EVADTEIIR-SCEMANAHGFIMQTTLK-YETNVGEKG-TQMSGGQKQRIAIARALVR------EPAILLLDEATSALDTE SEHLVQEAIYKNLDG--KSVILIAHRLSTVEKADKIVVINKGRVEQIGNHETLLKDTNGTYAKLVQRQMMGDQK----PR KRPAVARSG----PQPAASINVAGPSQGNAMSLLSTSFSQSASSVTSH---- >Cel-HAF-9 -------------------MSSSLYTGGQALFICLAFIGLDLLVNVFGLAWNGKYFTFDNIAHWFDLANYSFLKNPVDFL AVALIRDSILLGGAVSAWASPSGFSQVAENVKNVVFAMMLLIVAFAPSKLLAFYE------DDNIRLAVGDWILMIWC-- --------------IFASLLLQGIWTSVLAHVTE------------VAAGTGDSLLFGDAEHEERLRQEEAEKAAE---- ------------QRETFQLLFRLLGYMGRQWKYYGMAFFFLFCYSLSRVFIPYYTGEVVTAVFGDKAS------------ ------YEKLHKTVFIMGMLSLASTVFGGLRGGSFTYAHATIDRQIRNDLFRSVVKQEIGFFDMNK--TGEICSRLSADC QTMSNTLSLYMNVLTRNLTMLFGSLIFMFTLS-WKLSMITLINIPIIFLVNKIFGVWYDMLSEETQNSVAKANDVAEEVL SSIRTVKSFACENYESSRFMTFLNVTLKIATRKVFVVIGLIWSNELLQMGILTI-VLWYGGHLVIENKVESGLLVSFLLY QFQLGENLRELGEVWNGLMQAVGASRKVFEFIDRPPRVENTG---TYAPDGMTGKIEFRHVAFSYPIRPDLPIMEDLTFT VEPGEVVALVGPSGGGKSSCIAMLEHFYEPTSGEVLIDGVPVREYDHKFLH-TKVALVGQEPVLYARSVTENIGYG---L DKYDDDMVQNSAKLANAHTFIMNDTTDGYNTNVGEKG-SQMSGGQKQRIAIARALVR------QPVVLLLDEATSALDAE SEHTVQEAISKNLKG--KTVILIAHRLSTVENADKIVVINKGKVEQLGNHKTLMEQE-GLYKQLVQRQMMSGEDGLDDEI EEPEPAREGGSGRSTRAGARRIRSPSQSVSQSFLGTSFASSYL--------- >Bm1_15490 ------------------------MABCTRANSPORTERFAMILYPROTEINMIILFWDYIALNVP---YQFITSPVDFL VFTVVRLLIMLFCLMLKVSR---EYPWLEKLFIPFLGVFILHWTFSLIKLLAFSE------KIEQFAYFGFWLNVTWN-- --------------VLAAIFIMLLWNFVLRRNT---------------SWDYQSLT-GETRDVPSRLHDTKEEST----- ------------RFGTGQHILRLLRYCKFHWIWFAT----------ARVFLPYCTGQVLSNIVQGRG------------- ------AVVLVRSVLLMVALTFVSTITGGLRGGSFVYATALVNRQMRYDLFNSLVEQDISFFDTTN--TGEITSRLTTDC ETMSSTVSTNLNVFLRNIVMLLGSLVFMITLS-WRLSLVTFIIVPVVGFITKVYGAYYDLLTEKTQGTIATSNHVAEQVI STMRTVRSFACEKREARKFQQHLDETLNLNKKKAIVYMGYMWTTEFCDNAILIA-VLFYGGHLVLSGKMTVDNLISFLLY QMQLGENLYNISYVFTGLMESVGASRKVFEYMMRKPKILHVG---TKKTP-VNGEVKFDSVSFTYTSRPNNPVLQDVSFT VHPGQTVALVGPSGGGKSSIVSLIEHFYECDKGCVLIDGNPVADYDHEYIH-QKIALVAQDPILYEGTVRDNIVYG---C DWATEEDVLNAAKIANAHNFIMETEKQ-YDTNCGEKG-IQLSGGQKQRIAIARALVR------HPAILILDEATSALDAE SEHVIQDAIAQCSKD--KTVIVIAHRLSTVENADQIIVINKGRVVQQGRHDDLLEQ-DGIYRALVHRQLLGHSSSKIH*A A--------------------------------------------------- >nDi.2.2.scaf00101 -----------------MYKWSTLLLIILYCCLDIVISVVAFGFYQTSFKFDAHIIR-DYLTLNVP---YYFISSPVDFL ILTTVRLLVMLIFIMLKINR---EHSWLEKCFISLVGLFILNWTFSLIKLLAFSE------KIAQFAYFGIWLNIIWN-- --------------VLAAALIIVIWNFAFRINT---------------SWGYHSLTSGETRDSTSRLQGTKDEFN----- ------------RFGTYQHIIRLLQYCKYQWKWFASGFFFLIIYSLSRVFIPYFTGRVLSNIVQTRG------------- ------FAVLIRSVLLMSVLTFVSTIAGGLRGGSFSYATALVNRRMRSDLFSSLVEQEIGFFDATN--TGEITSRLTADC ETMSSTISTNLNVFLRNSVMLLGSMVFMTTLS-WRLSLVNFIVVPIVGFVTKVYGTYYDLLTEKTQGTIATSNHVAEEVI STMRTVRSFACEKREAKKFEQRLDETLHLNKKKAIVYMGYMWTTELCDSVIMIA-VLFYGGHLVLSGKMTVDNLISFLLY QMQLGENLYNISYVFTGLMESVGASRKVFEYMLRKPKILQVG---TKKTQ-INGEVKFDSVCFTYASRPNNPVLQDVSFT VHPGQTVALVGPSGGGKSSIVSLIEHFYECEKGWVLIDGNPVADYDHEYIH-QKIALVAQDPILYEGTVRDNIVYG---C DWATEEDVLNAAKIANAHNFIMETEKQ-YDTNCGEKG-IQMSGGQKQRIAIARALVR------RPAILILDEATSALDAE SEHVIQDAIAQCSRD--KTVIVIAHRLSTVENADQIIVINKGRVVQQGRHKDLLKE-DGIYRSLVHRQLLGHNSSKVD*- ---------------------------------------------------- >Cel-HAF-2 ------------------------------MLIDAAITNVSFGYFAPGWKFNYDSFL-GIITFSLP---YHFTTTPYEFQ IFSFIRQSFCAIAVLLIILN---KREKVKVLFPVVICNAVVVYSLSLIKFLAFSE------DSNQLYFPGLWFSVIWS-- --------------ILSGFIQVLVWYFVFTSN----------------PFDYHRLLNTTAENAGTSVTETAAETVRDTET ASNVESGSSTAPRAPLHKVLLRLLSYCGHQWPWFASGFVFLTVYALARVFIPNYTAQVISDIVNKRG------------- ------IQALIHSIIVLTCLTATSSLFGGLRGGCFDYATALVTLRIRLDLFTSLIRQDIAFYDTAK--TGDTMSRLTSDC QTISSTVSTNVNVFMRNGVMLIGALAFMILMS-WRLAMVTFIAVPLVGFITKAYSSFYDKISEKLQQTIAETNQMAEEVV STMRTVRSFACEKKELKRFEDRLSSTLSVNRKKSIAYLFYTWNNEFCDNAILVA-VLFYGGHLVMTGKMEKEQLITFLLY QMQLGENLYYLSYVMSGLMEAVGASRKVFDLMNRKPQFELDG---MQRPF-VNGNITFSHVGFTYPSRPNNPVLKDLTLS IKSGETVALVGPSGGGKSSIVSLIEHFYEPDEGSVTLDGVPIKDINHVYYH-QKVALVAQEPVLYNGSVRHNILYG---C DFATEDDMLNASKMANVHDFVMELEKG-YDTNCGEKG-VQMSGGQKQRIAIARALVR------NPAVLILDEATSALDTE SEALVQQALSRCAQE--RTVIIVAHRLSTIEKANKIAVIVKGCLVQMGTHTELMTDTDGMYYSLVSRQML---SAKVGED ---------------------------------------------------- >Cel-HAF-8 -------------------------------------------------------------------------------- ------------------------------------------------------------------MRISCSKSVPFS-- -----------------DLININTGAAG------------------------------EIVDKND------DEEEN---- ------------RLPLSEHLWEIVKLCGKQWRWFVPAYTLLILDCALNLIEPALYGQMMTNAIQMKS------------- ------FDIIKRACLLLALIQFSEATCKSACYFFMQYAEKLTARNIRIQLFRSILHQEISFFDENK--TGQLVSRITHDS ESISNTLPVHIETLVNNLFMFFGSIPIMFCYS-WQLTLTSFIEFPITLLMTRYYGLAVEKLSEKENDATAASNETVEEVL SAIRTVRSFAAENFEQKRYTKNTEDWFKISTKTVTLGTIYNYFWALMLRSQDVI-RYLYGGYLALNGRMAPEALLTFIFY HWRLHTAINAFSSLFSGVMKTIGLSRKVIHLINRKPQLDYDF---GTETPEIQGKIEFEVVEFAYPTRKTVNVINGINLS IESGKTVALVGPSGNGKSTLVSLIQQFYTPQSGRILTDGIPIQNINHQHYH-SNIALVAQEPTLFSGTIRENILFG---I ENGTEEAMLKAAEMANVHEFVSKMDDG-YDTKCGEKG-VQMSGGQKQRIAIARALIR------NPRVLILDEATSALDSE SEGMVQEALNKCAKE--RTVIVIAHRLSTVRKAQKIAVIENGSVKEMGCHDELMENQDGLYYKLVSKQLGSIVDTNIFNC FDMLIFFVLF------------------------------------------ >Cel-HAF-7 ----------------------MKPILLKLLLLLHVIFDISFTIISLGFYTPGWVFNLDDVFKTFHINDYNYMISPLDFV GLCLFRQVSLLVALIIVRRG---KAERLKKYMTIYDLFGILGYMIAVVKLLVFDETSGFLKSPGVFMSVGSAVFLTFSLP FAIRKTLLGKKKEGAEYERLTENTETAANTNVENGTASTNGTASTATPTAATSSTSRSSSTDEEDNDAVSKEEKEK---- ------------RLPLLTHLWQIVKLCSVQWKWFSAAYVLLFVDCILNLIEPALYSQMMSTAIRMKS------------- ------FDVLKRACIVLAAVQFTEATVNTVRYICMQYAERLTARNIRVSLFRAILHQDISFFDDNK--TGQLMSRITKDS ESISNSLPVYIETTVNNSFMLFGSAPIMFYYS-WQLAISTFVTFPIILLTTKFYGLIVEKLSEKENDATAVSNETVEEVL SAIRTVRSFAAEKIENMRYTRDTDAWFKISTKTVVFGTFFNYFWATMWNIEDVI-IYLYGGYLTLNGRMEPDALLTYIFY HWRLHSALNAFSSLFSDVMKTIGSSRKVIHIMNRQPELDYEF---GTETPEIVGNIIFEDVEFAYPTRKNANVLNKINLS IDPGKTIALVGPSGNGKSTLVSLIQQFYTPQSGRILIDGTPIQNIDHLHYH-TNIALVAQEPTLFSGTVRENILYG---L ENGTDEDMMRVAEMANVHEFVSKMEKG-YDTKCGEKG-VQMSGGQKQRIAIARALIR------DPRVLILDEATSALDSE SEAMVQEALNRCARE--RTVLVIAHRLSTVRSADRIAVIEKGNVTEMGNHEELMKNTEGLYYKLVSKQLDPLIGTKKEEE KPPATEFF-------------------------------------------- >Bm1_50255 --------------------------------------------------MABCTRANSPORTERFAMILYPROTEINMN IACISRRLFCTRCGLRKPSPSFSTSNRFLYTIFYPKSLIVLHRLN-SGGLRRNTYLF-----LVRSLSKAAKREPA---- -------------------------------------------------------------------------------- ----------KVRNVRWKDLRDIFSLAYPCRRRIYTGLLFLVIGNAIGLILPRIIFMFIDIDGNCEKEGDVRENKTDEKN MYFILAAKYLRVHYMVLFGLFCIAAASYGIRHYCMHTAGQLVINNLRQAVFRSVIHQDMNFFSKNK--VGEIVSRLSTDA LIVGQSVSSNLTVGARAFMSFFGSAVIMVYTS-RELSEVVTCLTAAIITSGYCFGNLQRKYTLQMQEVVAASNEVATEKF SNIVTVRTLVSELKECETYKKRIHQLWVVSCREGRAAGCMIALHEIAILASLYT-IVYYGGQLMNIGTLTYGDLLAFIWY ASLCALSLPGMVNFYTELMKGLGASARLFELRNRIPEVPVRG---GLLKRSITDGITFKNVSFGYPNRP--LLFTDVSFH IPAGKTTAVVGPSGSGKSTIANLILRLFDSNSGHILIDNDDLKSIDPSFWR-QQIGTVAQEPILFSTTIRNNIIYGSKHP ELIMDVQLEEASDLANALNFIKNLPDG-FETVVGEHGTSMLSGGQRQRIAIARALINACFKIKDPMMLIMDEATSALDAT SEDLVRKAILKLIKDSKKTVLIIAHRLSTIKYADQIVVINNGRVEEIGTFDELMLIEDGVFKNLVEKQAVSFS*AA---- ---------------------------------------------------- >nDi.2.2.scaf00023 ------------------------------------------------------------------------------MN ITCISRRLFYTRCNLRKRSPSFSTSTRFLFTMSYPKSLTDLYRMNNSGNLKRITHSF-----LIRNLSKAAKREPA---- -------------------------------------------------------------------------------- ----------KVRNVRWKDLRDIFALAYPCRRRIYTGLLFLVIGNAIGLVLPRIIFMFIDIDDNHEKKEIVRENKSDDKN MYFILAAKYLRIHYMVLFGLFCIVAASYGIRHYCMHTAGQFVINNLRQAVFKSVIHQDMNFFSKNK--VGEIVSRLSTDA LIVGQSVSSNLTIGARAFMSFFGSAVIMVYTS-PELSEVITCLTAAIVTSGYCFGNLQRKYTLQMQEAVAASNEVATEKF SNITTVRTLVSELKECETYRKKIHQLWVVSRREGRAAGCMIALHEIAILASLYT-IVYYGGQLMNAGALTYGDLLAFIWY ASLCALSLPGMVNFYTELMKGLGASTRLFELRNRIPEVPVRG---GLLKKSITDGITFKNVSFGYPNRS--LLFTDVSFY IPAGKTTALVGPSGSGKSTIANLILRLFDSNSGHILIDNVDLKSIDPSFWR-QQIGTVAQEPILFSTTIRNNIIYGSKHP ELIMDVQLEEASNLANALNFIKNLPDG-FETIVGEHGTSMLSGGQRQRIAIARALIN------DPMMLIMDEATSALDAT SEDLVRKAILKLIKNSKKTVLIIAHRLSTIKYADQIVVINNGRVDEVGTFDELMLIENGVFKNLVEKQAIGFK*WVSCHR Q*MVYINKTKNNLEKNFL*FRIGMFRMFTSGFCIHIIMRSFRFFFSGWITLI >Cel-HAF-3 ------------------------------------------------------------------------------MS LLSHLSRLCCSKC-----SSIPSSSTRLFCFAPQVGRSTGFLKST----LIKSKQAF-----RNVSVVET-KRESY---- -------------------------------------------------------------------------------- ----------KLKNASWKDLKAILSLAGPYKWRIMLGISFLGISSSIFLFTPRVLGKLIDEWDETKQDKMDPNDK----- --ALLLARFFKENPIALAGVFMLGAIAIAARIYCMHTAGQLVINDLRKSVFNSVLRQDMAFFDKNK--VGEIVSRLSTDA LIVGYSVSMNLSDGARALITCFGSGGLMVYTS-LAMCKVIFVVVPVIVGTFAVFGKLQRKYTLMMQEAVAGANQVATERL SSVRTVRMLVAERKELAAYSDKINEIWQISKKEGLAKGFMFGSFQFTGYLALSS-ILFYGSNLISQGLLTYGELSSFCLY AVLSAGSLSAMSGFYLELMKGLGASSRLFELKNREPRIPLEG---GVQIGNVKDTIRFEHVAFGYADRD--PLFHNISFD VPAGKITAVVGSSGSGKSTIASLLLRLYDPTSGRILVDGTDLKDIDPSYWR-RHIGTVGQEPVLFSTTIKENIIYGSLEP ENVTDAEIVSAADQSNADEFISRFPIK-YDTKVGEHG-STLSGGQKQRIAIARALVN------KPNILIMDEATSALDAS SEYLVRIALNKLLANSKQTVMIIAHRLSTIKHADQIVVVDRGSVAESGSYDELIAIPDGIFRKLVEKQTFGFKNPESY-- ---------------------------------------------------- >Cel-HAF-1 ------------------------------------------------------------------------------MH CLCVLRSTLCCQMP--------TSTYRMLLQTKAVPVQIIKRDLT-----AKVKNQK-----LNQNIRRVDRRNAAY--- -------------------------------------------------------------------------------- ----------LLRHTTWKDLVELYEIAKPFRKWIFLGTSFMVVSSGIFLIIPRILGKLIDQFDSNTGVQKAEEVFT---- ---MKIAKYFKEQPMSLVGLLAIGALATAAKVYCLQIAGVNIVGSLRKMVYSSIIRQDMTFFDKNM--VGEIGSRHAADT VIVGYSVSSSLRAGVRAVLVGVGSIGMMLMTS-LELSTVSFLTAPIVMGIFKMFGRVQQQCTWQLQEVAADVNQTAIERM ANMKTIRMLSAEQQSIDEYCKKGELVLDISKTEALAKGSLIGSFQFTGYSAFSS-ILFYGSHLINTGHITYGELSSFCLY AVLAAASLSNISGFYNEVMKGLGASSRLLELKNAQPIMNLNS---GIKKTDITTSIQFENVSFAYAGRK--KTLENISFD IPRGKITAVIGPSGSGKSSIANLMLRLYDPADGRVTVDGVDLRDLNATTWR-HAIGTVGQEPVLFTCSIRENILMGTEHP EKVSQYELEEAAQLANALDFIQGFENG-FETMVGEHG-CKLSGGQKQRIAIARALIS------KPKIMILDEATSALDAT SDYLIRMTLDNLLKNHNLTVLVIAHRLATMQQADQVVYVNRGRIEGQGTFDEMMKIQNSIVEQEARRRGIPMNEQMSRVN TPVARGFSLKF----------------------------------------- >Cel-HAF-6 ---------------------------------------------------------------------MSILSKLSQIS IKSAVQSSKHCFSSYPWLHKPISRTTILKTWRICGFGAGLGAVTLRKAACAPKLSKR------IDHLRTTEDQNASMT-- -------------------------------------------------------------------------------- -------------------AGELWNLIKPFFGWFFAAVVCAILSAYINIQIPLCLGDLVNGIVKIIKDESNNLRS----- -----HFEQLKPSALHLMTLYVAQSALTFLYITFLTVLGERMATKMRSDLFQKLLHHDMAFFDSHK--SGELSARLNADV QEFKSSFKLCVSQGLRTFAQTIGCIGSLYFLS-PTMTMYTVAVVPGIILAGSAIGAGLRQLSRRAQGQSATASAVSDEAL TNIRTIRAFAMEKLESRLFDNELDKARAMQEQLGVGIGLFQAGTNLFLNGMILS-VLYGGSNLISKGEMTPGALMSFLVS AQTIQRSLSQLSIIFGTAIKGWTAGGRVLQFSRLEPSIPMDTG-VCIPYHSLWGDIKFEDVSFSYPTRPGHTVFENLTLS IPAGQVVALCGPSGEGKSTITHLLERFYEPKSGRVTLDGRDLRELNVEWLRGQVIGLISQEPVLFATSVEENIRYG---R PDATDEEVREAARAAHVDEFVSRFPSG-YSTVVGERG-AQLSGGQKQRIAIARAILK------NPPILILDEATSALDSH SEHMVQEALNNVMKG--RTVLIIAHRLSTIRSAQMIYVIKDKKALESGTHEQLMAKKGSLYRKLVEAHNVDS-------- ---------------------------------------------------- >nDi.2.2.scaf00496.1 -------------------------------------------------------------------------------- ------MNCFIRAVLQKQLHLSNRQTKIVHASFIYRNFIFASKRKPKSS---LWKYIN-----------GQIRKCFHPGA SSLTPMT------------FSLGEQISTAELVK----------------------------------------------- --------TMLR-SAWPKGNWKIRRLYIYSMALLIVAKMLNVYVPFLLKNVVNYYNEQVPANLQLSADSYSN-------- ---MFGIAAFSIIVTYGVARSGS-ALFNELRNALFARVAQYSIRSIARQI?LHLHSLDLSFHLNRQ--TGGMSKAIDRGT RGMAFVQSALVFNVVPTTIEVGMVSGLLYVNCGPSFTLATLGCLSTYTIATLGITKWRTKFRHQMNQADNDANNRAIDSL INYETVKYFNNES?EADRYDFFLKKYEVAALKTSTSLALL?FAQNAIFSGGLVA-VMCLAAAEIQKGTMNVGDLVLANTL LFQLSVPLNFLGSVYREIKQGLVDMQLMFSLLYLKSNIIEKPNAPVLKVDMRNSSISFRNVTFGY--LPGQHILKGLSLD IPSGKKVAIVGGSGSGKSTIIRLLYRLFDPENGEICINDQKISDVQLESLR-KMISVVPQDSVLFHDTIYYNIQYG---N PTASKEEVFYVSKLANLHDSVIRFKDG-YNTIVGERG-LKLSGGEKQRVAIARALLK------NAPIIVYDEATSSLDAL TEENIMSSMRNAVQQ--RTSLFIAHRLATIIDADIIYVLEHGKMIESGSHFELLAKPDSHYSSLWNSQHKYAEIIKSKKS TSYKHESEHLHLKSLDNRRDDSCCRSGGGCKR*------------------- >nDi.2.2.scaf00496.2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- ---------MLR-SAWPKGNWKIRRLYIYSMALLIVAKMLNVYVPFLLKNVVNYYNEQVPANLQLSADSYSN-------- ---MFGIAAFSIIVTYGVARSGS-ALFNELRNALFARVAQYSIRSIARQIFLHLHSLDLSFHLNRQ--TGGMSKAIDRGT RGMAFVQSALVFNVVPTTIEVGMVSGLLYVNCGPSFTLATLGCLSTYTIATLGITKWRTKFRHQMNQADNDANNRAIDSL INYETVKYFNNESFEADRYDFFLKKYEVAALKTSTSLALLNFAQNAIFSGGLVA-VMCLAAAEIQKGTMNVGDLVLANTL LFQLSVPLNFLGSVYREIKQGLVDMQLMFSLLYLKSNIIEKPNAPVLKVDMRNSSISFRNVTFGY--LPGQHILKGLSLD IPSGKKVAIVGGSGSGKSTIIRLLYRLFDPENGEICINDQKISDVQLESLR-KMISVVPQDSVLFHDTIYYNIQYG---N PTASKEEVFYVSKLANLHDSVIRFKDG-YNTIVGERG-LKLSGGEKQRVAIARALLK------NAPIIVYDEATSSLDAL TEENIMSSMRNAVQQ--RTSLFIAHRLATIIDADIIYVLEHGKMIESGSHFELLAKPDSHYSSLWNSQHKYAEIIKSKKS TSYKHESEHLHLKSLDNRRDDSCCRSGGGCKR*------------------- >Bm1_30435 -----------------------MABCTRANSPORTERPUTATIVEABCTRANSPORTERPUTATIVETRANSLATEDSE QUENCEMNYFLRTMLQKQFQLSNRQTKLV-----YRNFLSASKKNPKTSRTTLWKRIT-----------GQIRNCFHPGA SSLVPMAVSLMVAILNDLKFPLGKQISTAELVR----------------------------------------------- --------TMLR-SVWPKGNWKIRRLYMYSMALLVVAKVLNVYVPFLLKNIINYYNEQVPISLQLSADSYSS-------- ---MFGIAAFSVIITYGAARSGS-ALFNELRNAVFARVAQYSIRNIARQIFLHLHSLDLSFHLSRQ--TGGISKAIDRGT RGMAFVQSALVFNVVPTAIEVGMVSGLLYVSCGPSFTFATLGCLSIYTIATLGITKWRTKFRHQMNQADNDANNRAIDSL INYETVKYFNNESFEADRYDFFLKKYEVAALKTSTSLALLNFAQNAIFSGGLVV-VMCLAAAEIQKGKMNVGDLVLANTL LFQLSVPLNFLGSVYREIKQGLVDMQLMFSLLCLKSNITEKPNAPTLNVHMRNSSISFKNVXFGY--LPGQYILKGLNLD IPSGKKVAIVGSSGSGKSTIVRLLYRXFDPQDGEICINGQKICDVKLESLR-KMISVVPQDSVLFHDTVYYNIHYG---N PTASKEEVLSVSRLANLHDSVIRFKNG-YDTVVGERG-LKLSGGEKQRVAIARALLK------NAPIIVYDEATSSLDAL TEENIMSSMRNAVQQ--RTSLFIAHRLATIIDADIIYVLENGKVAESGSHFELLAKPASRYSELWKSQHKY-----SKQL TSHNQGPEHLHLGSFDNHRDDGCCRSGGGCKR*------------------- >Cel-HAF-5 MGFSPFLDECRAEGLWPIGPSCNKIISFGVYTFFIVVNFIVLCIPNSNSANNNYRRMTDDDASSTSKLTISKILSICTIF AVICQSIFYFCFTFYFHPYTHLLLAFCVSKLFFWILSLCSFSKWRNQPSTPISLAFAFSAALLIHCIPLTDWKKYFEPTS KNRGDLTFYIIELALVTVVFFFTIVTGLFNFSG----------------------------------------------- --------CSSRESAWNNLSKKVVTVAPYIWPTKSISLQLRVVFCLFLLIIGRLINVSLPILSKWIVDELATPDTF---- ---QYSLLFLATFLKFLQGNGAMGGFLNTVRTYLWIPIQQYTTRELEVELFKHLHSLSLRWHLSRK--TGQVLRVMDRGT SSVNNILNYILFNVVPTIADIVIAVIFFFSAFNAYFGLIVFGTMALYLTVTISITEWRTQYIREANEKDNATSAIATDSL INYETVKYYGNEEFEVNRFKNAIESYQVTEWKTQASLAFLNCLQNAIIGIGMIGGSVFVVYMIVHEKTLTVGDYVLFTTY LLQLYTPLNFFGTIYRVIQKAFVDMENMFDLMNDEVEVKDLP--HALPYTDPRGTISVKNLTFEY--NTGLPVIKNISFE IGNGQTVALVGSSGSGKSTLIRLLFRLFESTEGSIEFDGIDVRNYTMHSLR-QQIGIVPQDTVLFNDTIMYNIRFG---R PDASDEEVIEAAKAAMIHEKITSLPEG-YATMVGERG-LKLSGGEKQRVAIARTILK------KPQFIFLDEATSALDTP TERAIQKCLEKLCKS--RTGVVVAHRLSTVVNADLILVLDKGIILERGNHKELLAQQG-TYASMWEAQIAE------QRA KSIELGEELP------------------------------------------ >nDi.2.2.scaf0048.5 ----------------------------------------------------------------------------MDTP FKTNIMEVAMEDKDYDDQTLLPGKTTN----------------------------------------------------- -------------------------------------------------------------------------------- ----------------FNAIWNLIKSYKAGYSYLGVAIPVTVLRGFFFLLVCFEVSSVLEIALAPNEE------------ -----TAQQVFITAAVYTALIIIKTMFEAVGRLFIALYGHGFCGYMRNKMFRKILRHGATYFDEEANTPGRLVHKLMSDT ATLNRILGDKLDLLIPAVICSTVSVTIALLIN-WKLALICGFQFPAFFLFRFVELRETSKRHRQMAEQEKKAANLATSVL SNMSTIKAYTLQEHFNNIFYETLKPLQNTMKRQS-CISSFVFACQFSFTYILIAITLHFGKVMMLSNEITPFNYLRVVLL TQFGANFISQLIASVNDISKARVASGNILNVIK-ETAVDMNNLSDEGLRPKTTARLMLKNVEFRYPSRPLYSVLRNLTLK VRPGDSIAIVGPSGSGKSSILALFQRMYNTTKGEVLIDNYDVKQINPAYLR-RVVVSVEQEPTLFSFTIRENIGYG-LPE DEATEEKIVEAAKIANIHDFILSLPQG-YDTEVGEFG-AQLSGGQKQRIAIARAIIR------EPRVLLLDEATAALDTA SEKAVQSALESVSKN--CTCIYVAHRLSSIRSVNKIYVLVDGEIAEQGTHQELMEE-KGLYYEMNQSEI*---------- ----------------------------------------------------