Rapid Curtailing of the Stringent Response by Toxin-Antitoxin Module-Encoded mRNases

Supplemental material

• Supplemental file 1 -

  Fig. S1, (p)ppGpp accumulation upon valine-induced isoleucine starvation

  Fig. S2, ribosome trafficking model without abortion and mistranslation

  Fig. S3, sensitivity of parameters in ribosome trafficking model

  Fig. S4 and S5, model of early stringent response

  Fig. S6, predicted ppGpp response to amino acid starvation

  Fig. S7, mRNases reduce mRNA stability during amino acid starvation

  Fig. S8, early stringent response of ΔrelBE strain to isoleucine starvation

  Table S1, parameter values in the ribosome trafficking model

  Table S2, parameter values in the model of early stringent response

  PDF, 568K