% Pool model with PF odes, along with a PK model are coded in this file. 
% The file runs with run_pool_model_withPK.m
% Author: Suruchi Bakshi, LACDR, Leiden University

function dy = pool_pf_odes_wo_if_condition(t,y)
global ks kel kr ec50_de emax_de ec50_prl emax_prl bsl k_a Cl V1 V2 Cl12
dy=zeros(5,1);
% PK equations
dy(1) = -k_a.*y(1);% depot comptmnt
dy(2) = k_a.*y(1) + (Cl12/V2).*y(3) - (Cl/V1 + Cl12/V1).*y(2); % central comptmnt
dy(3) = (Cl12/V1).*y(2) - (Cl12/V2).*y(3); % peripheral comptmnt
% PD equations
dy(4) = ks.*(1 + emax_prl.*(y(5)-bsl)./(ec50_prl + y(5) - bsl)) - kr.*y(4).*(1 + emax_de.*(y(2)./V1)./(ec50_de+(y(2)./V1))); % Lactotroph PRL
dy(5) = kr.*y(4).*(1 + emax_de.*(y(2)./V1)./(ec50_de+(y(2)./V1))) - kel.*y(5);% Plasma PRL