Proteomic Analysis of the Spatio-temporal Based Molecular Kinetics of Acute Spinal Cord Injury Identifies a Time- and Segment-specific Window for Effective Tissue Repair

Supplemental Data

  • Supplementray data_legends (.xlsx, 1.4 MB) - Suppl. Data1: List of total proteins identified including the accession number, distinct unique peptides assigned for each proteins, the percentage of coverage of each peptide assigned.
  • Supplementray data_legends (.xlsx, 47 KB) - Suppl. Data 2: List of proteins identified per cluster depending on the time course post injury or the spatial localization with accession number, protein name and gene name.
  • Supplementray data_legends (.xlsx, 14 KB) - Suppl. Data 3: Neighbors pathways for exclusive specific proteins identified in R1 or C1 segment for each time course after SCI
  • Supplementray data_legends (.xlsx, 14 KB) - Suppl. Data 4: Neighbors pathways for exclusive specific proteins identified in R2 or C2 segment for each time course after SCI.
  • Supplementray data_legends (.xlsx, 15 KB) - Suppl. Data 5: Neighbors pathways for exclusive specific proteins identified in R3 or C3 segment for each time course after SCI.
  • Supplementray data_legends (.xlsx, 12 KB) - Suppl. Data 6: Elements exclusively found in lesion segment at 3, 7 and 10 days post SCI and common elements between each time course.
  • Supplementray data_legends (.xlsx, 10 KB) - Suppl. Data 7: Neighbors pathways for common specific proteins identified in R1 or C1 segment for each time course after SCI.
  • Supplementray data_legends (.xlsx, 11 KB) - Suppl. Data 8: Neighbors pathways for common specific proteins identified in R2 or C2 segment for each time course after SCI.
  • Supplementray data_legends (.xlsx, 11 KB) - Suppl. Data 9: Neighbors pathways for common specific proteins identified in R3 or C3 segment for each time course after SCI.
  • Supplementray data_legends (.pdf, 597 KB) - Suppl. Figure 1: (A-D) Cryostat section 50 ?m thick cut from control spinal cord segment R1 (5mm) cultured 24hr in vitro in DMEM showing preserved neurons and astrocytes. (A) Collocalization of NeuN positive (red) and GFAP positive (green) cells in spinal longitudinal section. (B) Higher magnification revealing positivelly labelled nuclei of neurons (NeuN) and (C) homogenously distributed network of astrocytes. (D) Merged B and C. Scale bars A= 200?m, B,C,D=100?m
  • Supp. Data. Legends (.docx, 14 KB) - Legend for supplementary data and figure