JNK Signaling: Regulation and Functions Based on Complex Protein-Protein Partnerships

Supplemental material

• Supplemental file 1 -

  Overview of JNK substrate proteins (Fig. S1), critical assessment of scaffold proteins implicated in the mammalian JNK pathway (Table S1), and sequences of mutually exclusive exons for the human JNK genes (Table S2).

  PDF, 914K

• Supplemental file 2 -

  JNK substrates with structurally reasonably well-established (canonical JIP1- or NFAT4-type) D-motifs (Table S3).

  XLS, 51K

• Supplemental file 3 -

  JNK substrates with weak, incomplete, or atypical D-motifs (Table S4).

  XLS, 38K

• Supplemental file 4 -

  JNK substrates with structurally uncharacterized JNK docking elements or devoid of direct docking (Table S5).

  XLS, 292K

• Supplemental file 5 -

  JNK substrate phosphorylation sites with questionable experimental evidence, sequence, or structural accessibility (Table S6).

  XLS, 262K