31 220 906476263_BeeMLV NIYIHAAHSP QGLSEYCQRH LKSQLALTND YTAFDQSQHG EAVVFEREKM 18138526_GFkV HLYIHAGQTP HQLSEWCQNH LTPSVHLAND YTAFDQSQHG EAVVLEAWKM 14141973_MRFV TLYVHAGHTP FEMADWCRAH LTPAVKLAND YTAFDQSQHG EAVVFERYKM 289522103_OlLV-3 HIYIHAGHTP QDMSNWCQQN LTDSIHLTND YTSFDQSQHG EAVVLEQMKM 459642390_APLV QLYIHCGHTP HQLSSWCQTH LSGQTYLAND YTSFDQSQHG EAVVLELLKM 21686952_TYMV NIYSHCGKTP NQLRDWCEHL THSTPKIAND YTAFDQSQHG ESVVLEALKM 76253627_SSDRV NVYLHREKTE QDFSTWVNGW NFSGHATIND CEAFDASQDG AFVEFERLHA 655454923_SSDRV2 RVYLHREKTE EDFSNWISGW DFSGHSTIND CEAFDASQDG AFVEFERLHA 37595816_BVX NVFIMCEKTS NQFNDFVKDW NFERDNYTSD YTQYDKSQDG LFLNFELRKA 18450252_GarVA NVFIMCERTP DQFNNFVTKW DFSRPNYTSD YTQYDQSQDA PFLNFELRKA 338826798_BVE NVFIMCEKTP AEFNDFVNRW DFKTPSYTSD YTQYDQSQDA AFLNFELRKA 169803201_LLV NIRINCEMQP QDISKWAQKW NFERPAFASD FEAFDQSQDG AMLHFEALWA 9627984_BaMV NILINCEIDQ PTASKWVTHW KFDRLAYTND FEAYDQSQDG AMLQFEVMKA 9626709_FoMV EILINCEKNQ KHISKWVSNW NHRLPAYTND FTAYDQSQDG AMLQFEVLKA 14602400_CVX NIMINCERTP EELTSWAEHW NFNRNSYAND YTAFDQSQDG AMLQFEILKA 215481431_MVX EVFINCETTP EDMSVWANNW NFSRPSLAND YTAFDQSQDG AMLQFEVLKA 764160353_CYVCV_CQ EIMINCETNP NQIGTWVEYW NFNTQSHEND FEAFDQSQDA NMLQFELIKA 11125723_BvF HVYIHSRRTN EDFEKFVAHW DHTRESTDGD YTAYDASQDA TFVNFETLLM 20153360_GVA KLMIYSQKKY MDLDKWAKTW VESMMGTDSD YEAFDRSQDE KVLDLEVEVL 9629174_ASGV SYYIHSGKNF FCLDSFVNAS VFDGFSIESD YTAFDSSQDH VILAFEMALL 194351514_PVT SWYIHTMKNF DQLNNWVINY VDQEEGTESD YEAFDRSQDA IILGLEIECL 315506977_ApLV NLYIHSGKNI DDLASWVRIH KFNGVCTESD YEAFDASQDH FILAFELEVM 166851939_LNRS QYYIHSGKGL DELNAWVKEG KFEGVCTESD YEAFDASQDQ YIVAFEVNVM 9626090_PVM NYYIHSGKGL EELDAWVKKG KFDRICTESD YEAFDASQDE FIMAFELELM 171473628_HpMV QYYIHSGKGL SELNDWVKRG SFAGVCTESD YEAFDASQDE YIMAFELELM 14251191_AcLV NYYIHSGKGL GELNDWVKRG KFQGVCTESD YEAFDASQDE YIMAFELELM 226309582_AOPRV QFYIHSGKNF DDLNDWILNA DFSRVCTESD YEAFDSSQDS NILAFEVSIM 9630734_CGRMV NYYIHSGKNF DELRSWVLRN SFTGMCTESD YEAFDSSQDA NILAFEVSLM 20889382_CLBV EIYIHSNKNF DDLNAWVKKF FQRDICVESD YEAFDASQDE YILSFEIHLM 9626206_ACLSV NYYIHQRKNF SELEDFARRF SNGSICVESD YTAFDVSQDH TILAFEVELL newGnemo_GTHK-0070069 EVYIHAGHTP LEMAKWCREN LTTRTKVAND YTAFDQSQHG EAVVFERLKM AQLGIPQQLI DLHVFLKTNV ETQFGPLTCM RLTGEPGTYD DNTDYNLAIL RRASIPEPFI TLHVHVKTNI ECQFGPLTCM RITGEPGTYD DNTDYNLAIL NRLSIPAELV DLHVYLKTNV STQFGPLTCM RLTGEPGTYD DNTDYNIAVL ARLSIPQHLI DLHTHLKCNV STQFGPLTCM RLTGEPGTYD DNSDYNLAVI QRLNFPSFFL DLHLHLKTNV QTQFGPLTCM RLTGEPGTYD DNSDYNLAVI KRLNIPSHLI QLHVHLKTNV STQFGPLTCM RLTGEPGTYD DNTDYNLAVI EFLGVPRELI DFYVDTKIKS YIWRGTISVM RLSGEGPTYD FNTWANMAFM QFLGVPEELI DFYVDTKVKS YIWRGTIAVM RLSGEGPTYD FNTWANMAFM RHFGVPQAVL DAYTAIKTDA KVFADTLKIM RLSGEGPTFD ANTECNIAYD RHLGVPDEVL SFYKFIKTHA KTFVGNLAIM RLSGEGPTFD ANTECNIAYD RHLGVPEEVL DFYKFIKIHA KTFVGNLAIM RLSGEGPTFD ANTECNIAYD RHFNVPSSLI EEYLFLKMHA QAPKGYLTIM RLTGEGPTFD ANTACSIAYN RHHDLPADLI ESYIELKLNA KIFLGTLGIM RLTGEGPTFD ANTECNIAYT LHHDIPHEVV EAYVALKLNS KMFLGTLAIM RLTGEGPTFD ANTECNIAYT RHHSIPEVYI EGYLDLKCSS MTFLGILKIM RLTGEGPTFD ANTECNIAFA KHHCIPEEII QAYIDIKTNA QIFLGTLSIM RLTGEGPTFD ANTECNIAYT KYHSIPEEII AGYRHLKCNA HIFLGTISIM RLSGEGPTFD ANTECSIAYN RRLDFPLDII EAYVEMKASI TSHFGPLAIM RFSGEVWTYL FNTLGNIAFT RFFLWPEDLI REYEELKLMM GCALGDLAVM RFSGEFGTFF FNTVCNMVFS QYLGVSKEFQ LDYLRLKLTL GCRLGSLAIM RFTGEFCTFL FNTFANMLFT KLFGWDQDLI DDYRKLKLRM GCRWGAIAIM RFTGEFGTFF FNTIANIAFT KYLGLPADLI SDYTFIKTHL GSKLGNFAIM RFTGEASTFL FNTMANILFT RYLGIPNDVI NDYVFIKTHL GSKLGNFSIM RFSGEASTFL FNTMANMLFT KYLRLPSDLI EDYKFIKTSL GSKLGNFAIM RFSGEASTFL FNTLANMLFT KYLGLXHDLV EDYKFIKTSL GSKLGNFAIM RFSGEASTFL FNTLANMLFT RYLRIPGDLI EDYKYIKTSL GSKLGNFAIM RFSGEASTFL FNTLANMLFT KFLHIPVDLI SDYIYLKQNT VSKLGAFATM RFTGEAATFL FNTMANMVFT RYLRLPRDLI EDYKYLKFNT RSKLGQFAVM RFTGEAGTFL FNTLANMVFT KDAHFPQKII DAYIDLKCKL GCKLGHFSIM RFTGEFCTFL FNTLANMAFT RHFGWDDRVL QSYIKMKCTL GCRLGGFAIM RFTGEFSTFL FNTLANMVFT ERLNIPRNLI DLHVHLKCNV ETQFGPLTCM RLTGEPGTYD DNSDYNLAVI SLRYLLHQHV VFVSGDDSAI FPPPSDNPRW KVIEPLIALR FKIQIDRYPL YTQYLLHRTP VLVSGDDSLV DRVPPMNPSW PALAPLFALK PKPETSPFGL HLEYAVGSTP LMVSGDDSLL DSEPPVRDQW SAIAPMLALT FKKERGRYAT HLQYAVGSTP CMVSGDDSLL DSKPPIRDEW TGIAPLLALR FKTELDRYSL FSKYLIHSHP IMISGDDSVI CGNPSIHPSW SSIEPILHLK FKTETNSHPL YSQYDVGSCP IMVSGDDSLI DHPLPTRHDW PSVLKRLHLR FKLELTSHPL ATKYSISVAM TAYSGDDFAC DQVLSVKPAF KELECRFKLK EKRFLKSQAD ATKYSIKAAM AAYSGDDFAC DRVLSIKPAF RELESKFKLK EKRFLKTQAD AARFQLSDVK ACYAGDDLAR DRNCPERASW KYISHQFTLQ AKPLVTRKPD ALRFRLDNVR ACYAGDDLVR DRACEERAGW VYSERLFSLK AKPLVTSKPD ALRFKLPTVN ACYAGDDLVR DQVCDERPGW QLSKHLFTLQ AKPLTTTTPD HTRYEIKSCM QLYAGDDMLL DQVPVEKTGF KNIAAGLKLT AKTEIFEQGE HARFHIRGTA QLYAGDDCAL NCEPEERESF KPLAAQFTLK SKPVTIRQPE HARFEIKNVA QMYAGDDCAL NCRPVERQSF LPLVEKFTLK SKPKVFEQPE HTKLKIIGTA QLYAGDDCAL ATVPEDKPSF KMIETEVSLK AKPVIKRQAE HTKFDIAGTA QVYAGDDSAL DCVPEVKHSF HRLEDKLLLK SKPVITQQPE HTRYFVKGTA QLYAGDDSAC ASPLSEKPSF QHISPELSLK SKAKIRTQAT YAKYEVSVAQ V-YGGDDKSI NSPITVRTGW SQLVGKFNLV EKPVVGYEPT CMRYHIRNTP MCFAGDDMYS PGILRVKKDY EATLDQLTLK AKVHISEEPL QLKYKIRRHR ILFAGDDMCS LSSLKRRRGE RALMKSFSLT AVEEVRKFPM CLRYNIRDTV IAFAGDDMYA SGKLEIRKDR EDLLAHLTLK AKVQFTEKPM FLRYDLGKEA ICFAGDDMCA NSRLKITNKN SKFLDKIKLK AKVQFTVTPT FLRYSIGNEY ICFAGDDMCA NTRLHISKEH ESFLGKLKLK AKVDNTNHPT FMRYNIGDEF ICFAGDDMCA SRRLQPTKKF AHFLDKLKLK AKVQFVQFPT FMRYDIGNEF ICFAGDDMCA NKELKVTGAY KGFLDKLKLK AKVQMTGTPT FMRYEIGNEF ICFAGDDMCA PTHLQTTGRH KSFLDKLKLK AKVQFTGKPT FMRYSIKFDK IAFAGDDMCA NRNLPVTNAF EEILSRMKLK AKVLRVRNPT FMRYDIGKES ICFAGDDMCA NKRLRKKSEF EHILDRMTLK AKVQYTTEPT MCRYEWRGQP IAFAGDDMCA LNNLAVCHDF DDLFELISLK AKVERTETPM FCRYEVDGTP ICFAGDDMCA LRNLREIDTH EFILSKLSLK AKVNRTKVPM FLEYHAEGHP IMVSGDDSLI DSIPPSRANW SGIEPLLALR FKKEVGKLAL FCGYYLGPAG ACRDPLALFA KFAIAYDALE LKMPSYIAEF SIGHLLGDAV FCGYFVGPAG AVRAPRALFA KLAIALEDLP EKIASYVAEF SVGQSLGDSL FCGYYVGFTG AVRSPPALFA KLMIAVDDIS DKLIAYLTEF TVGHSSGDAF FCGYFVGSSG AVRCPRALFA KIMIAVDDIP LKIASYLTEF SIGHSLGDEF FCGYYVSPLG AVRNPFALFA KLMICIDDLD DKILSYLSEF SVGHTLGDSL FCGYYVGPAG CIRNPLALFC KLMIAVDDLD DRRLSYLTEF TTGHLLGESL FCGMIITPNG VIKNPRKLYL SLKSHDEIID KAIVNYYNDL RTLISLGDNI FCGMIITPSG VIKNPRKLYL SLKGHVEIID KAIVNYYNDL RTLISLGDNI FCGWSLTKHG IVKNPKQLWQ SMQLGLKLLK DIVPSYSLDF HHAYALGDKV FCGWRLTPHG IVKSPIQLYQ SLQLALRLVE DVKRSYAIDY LFAYRLGDKL FCGWRLTPHG IVKSPIQLYQ SLQLALRLME EVKRSYAIDY SYAYKLGDKL FCSWWMTPYG LVKDPITLYH RILLASEILS KKIDAYAIEA EPAYALQGRL FCGNIITPYG YLKHPRKTWA ALHKAKLQLK KTATAYALDV LPTYELGDAI FCGNLITPRG YLKDPMKLQH CLQLAQRKLK DVAENYAMDL LPTYELGDAL FCGMLVTPLG VIKDPIKTWA ALKLAEKKHE RHEGQLLKEL GLVYQHKDPL FCGWLITPKG VMKDPIKLHV SLKLAEAKLK KCQDSYEIDL SYAYDHKDSL FCGWLITPKG LIKNPTQLYA SWLLAKHNLA DVARNYALDL RIAYQLKDEL FCGWRIVPGG IVKDPQLLFW RTRYARIRAA LWAPGYYDEL VLSLKTSDRL FCGWRMSPFG IIKEPNLILD RWKIALRSLS LCLVNYAIEA SFGYRLSEHL FCGWYLSPYG IIKSPKLLWA RIKMMSERLK ECVDNYLFEA IFAYRLGERL FCGWYIKKMG IVKEPRLVLE RWLIAERKID QCFINYSIEV SYGYRLGEYL FCGWGLCEHG VFKKPDLVLE RLQIARETLE NCIDNYAIEV SCAYQMGENL FCGWNLSAHG IFKKPQLVFE RLCIAKETLG NCIDNYAIEV SFAYKMGELA FCGWHLCPDG IYKKPQLVLE RMCIAKEMLS NCIDNYAIEV AYAYKLGEKA FCGWHLTPDG IYKKPQLVLE RMCIAMELLH NCIDNYAIEV AYAYSLGEKA FCGWHLCPDG IYKKPQLVLE RMCIARELLA NCIDNYAIEV AFAYQLGEKA FCGWCLTKFG IYKRPQLVAE RLIIAIERLA DCIDNYAIEV SYAYNLGERL FCGWRLGDFG IVKRPQLVQE RILIALEKFH ECIDNYAIEV SYAYNLGERL FCGWRLTPYG IVKEPELVYN RFQVAIEEVL ECLENYAIEV SYAYSLSERL FCGWRLCCDG LIKEPCLIYE RLQVAIENLM DVIDSYFLEF SFAYKLGERL FCGYYVGAAG AIRSPKALFA KLMIAVDDIK DKMAAYLTEF AIGHTLGDSL SSLLPPSHIL FXSAVFDLIC WSLIPPELVI YQSACFDLIC WTILPVEAVP YQSACFDFFC WQLLPVEQVV FQSACFDFFC IHVIPSAILP YQSACHDFFC WHLLPETHVQ YQSACFDFFC FSALDATETE FFAGCLNVVH FTVLDSTETE FFAGCLKVIH YDIFTEEEMA YHQATVRLMH YDIFDEEELE KHQLVTRTLI HEVFNEQELD AHQLTTRIFV FDCFNEEQMT AHYGTIRRLI HDIFTDNELT FHYQTIRTLH YEIFDERQMN AHYQSVRTLI HSIFSESNPW PTKLTVRKII HDLFDEKQCQ AHTLTCRTLI YELLSPEELD HHQLLVREMI MDHMSPNDLA YLQALVRFYT YDVNI--DVD AQQELVREIV YTILKEEDFE YHYLVIRFFV WEYFD--NLE DFQAIVRLVI NLYLSPHEMD AHYNCVRFII IQQMNEEEVD AFYNCVRVII VNRMDEEEVA AFYNCVRIIV VNRMSEEEVG AFYNCVRIII LNRMDEEEVG AFYNCVRIIV VSIMSEKEVE SHYFCVRTII ISIMSEKELD AHYFCVRTFL YEVLSERQVQ YHQAVVRFIV YSHLEIEQLN YHQVLTRFFI WSLIPVDHVM FQSACFDFFS Supplementary file 5. Alignment (Phylip format) of RdRP from viruses in order Tymovirales.