Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation

Data Supplement

Files in this Data Supplement:

• Supplemental Data -

  Expanded Methods

  Supplemental References

  Supplemental Table 1 - Arrhythmia and Echo Data from HopXTg Mice

  Supplemental Table 2 - Clinical Characteristics of Heart Transplant Recipients at Explant

  Supplemental Figure 1 - Hypothesized involvement of members of class I HDAC in the process of atrial remodeling and inflammation

  Supplemental Figure 2 - CI-994 reduces atrial cytokine expression in dogs with sustained AF

  Supplemental Figure 3 - Atrial fibrosis is increased in human left atrium based on heart failure etiology and with atrial fibrillation

  Supplemental Figure 4 - Heart failure and chronic AF increases human atrial cytokine expression