The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction

Supplemental Material for Lavinsky et al., 2016

Files in this Data Supplement:

  • Figure S1 - ABR permanent threshold shift at 4kHz (a), 8 kHz (b), 12 kHz (c), 16 kHz (d), 24 kHz (e) and 32 kHz (f) tone burst in 100 HMDP inbred strains. (.pdf, 424 KB0
  • Figure S2 - GWAS results for ABR permanent threshold shifts in the HMDP at 4kHz (a), 8 kHz (b), 12 kHz (c) and 16 kHz (d) tone burst in 100 HMDP inbred strains. (.pdf, 166 KB)
  • Figure S3 - GWAS results for ABR post-noise exposure thresholds in the HMDP at 4kHz (a), 8 kHz (b), 12 kHz (c), 16 kHz (d) and 24 kHz (e). tone burst in 100 HMDP inbred strains. (.pdf, 244 KB)
  • Table S1 - Top 50 cochlear genes correlated with ABR hearing thresholds after noise exposure. (.pdf, 234 KB)
  • Table S2 - Top functional annotation cluster for the genes correlated with hearing after noise exposure (Enrichment Score: 6.51). (.pdf, 20 KB)
  • Table S3 - Top functional annotation clusters for the 1,363 genes regulated by the top 300 trans-eQTL hotspots. (.pd, 122 KB)