{"text_format":"2","workbook":"xlsx","n_sheets":7,"sheets":["Key","MeOHvsAce","MeOHvsTMA","TMAvsAce","edgeR","DESeq2","PoissonSeq"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":0,"defined_names":0,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900"}

{"sheet":"Key","index":0,"n_rows":7,"n_cols":2,"rows_kept":7,"cut":false,"hidden":false,"merged":[]}
["Sheet","Description"]
["MeOHvsAce","Differentially expressed genes with p<0.01 comparing MeOH to Acetate growth as called by all three methods: DESeq2, edgeR and PoissonSeq."]
["MeOHvsTMA","Differentially expressed genes with p<0.01 comparing MeOH to TMA growth as called by all three methods: DESeq2, edgeR and PoissonSeq."]
["TMAvsAce","Differentially expressed genes with p<0.01 comparing TMA to Acetate growth as called by all three methods: DESeq2, edgeR and PoissonSeq."]
["edgeR","All genes called as differentially expressed with p<0.01 by edgeR comparing all three growth substrates."]
["DESeq2","All genes called as differentially expressed with p<0.01 by DESeq2 comparing all three growth substrates."]
["PoissonSeq","All genes called as differentially expressed with p<0.01 by PoissonSeq comparing all three growth substrates."]

{"sheet":"MeOHvsAce","index":1,"n_rows":202,"n_cols":11,"rows_kept":202,"cut":false,"hidden":false,"merged":[]}
["Gene","COGClass","arCOG","COG","Function","edgeR log2FC","edgeR p-value","DESeq2 log2FC","DESeq2 p-value","PoissonSeq log2FC","PoissonSeq p-value"]
["MA0002","-","-","-","-",1.388826,1.3E-005,1.182815,9.2E-005,0.951235,0.035104]
["MA0006","E","arCOG00119","COG0076","Glutamate or tyrosine decarboxylase or a related PLP-dependent protein",1.069106,4.9E-005,0.953596,4.1E-005,0.739549,0.052065]
["MA0010","C","arCOG02695","COG2037","Formylmethanofuran:tetrahydromethanopterin formyltransferase",2.475101,2E-006,1.710356,1.3E-005,1.712926,0.027687]
["MA0026","-","-","-","-",1.391121,4.3E-005,1.12781,0.000615,0.965271,0.036264]
["MA0034","C","arCOG01600","COG1014","Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit",2.215157,1E-005,1.56594,6.7E-005,1.536022,0.025711]
["MA0086","O","arCOG05154","COG0459","Chaperonin GroEL (HSP60 family)",2.886649,0.000118,1.482953,0.001436,1.997914,0.052065]
["MA0089","S","arCOG02290","COG2043","Uncharacterized conserved protein, DUF169 family",0.794797,0.00032,0.705459,0.002638,0.546726,0.060654]
["MA0126","S","arCOG04844","COG4033","Uncharacterized protein",0.96301,0.000795,0.836386,0.004937,0.652468,0.0538]
["MA0183","J","arCOG04113","COG0197","Ribosomal protein L16/L10AE",1.890886,0.000506,1.202955,0.006763,1.309594,0.028065]
["MA0202","E","arCOG02230","COG0066","3-isopropylmalate dehydratase small subunit",2.324325,3E-006,1.423696,0.001432,1.609031,0.025711]
["MA0217","E","arCOG02208","COG0040","ATP phosphoribosyltransferase",1.058151,0.001103,0.885611,0.003631,0.735964,0.054278]
["MA0334","V","arCOG01731","COG0534","Na+-driven multidrug efflux pump",1.127767,3.4E-005,1.012398,5E-006,0.782137,0.052065]
["MA0438","-","-","-","-",0.959222,0.000772,0.859519,0.000179,0.655087,0.060603]
["MA0455","-","-","-","-",6.210709,0,4.129899,0,4.313586,0.027687]
["MA0456","C","arCOG02032","COG5012","Methanogenic corrinoid protein MtbC1",6.004217,0,3.936698,0,4.177159,0.027687]
["MA0457","-","-","-","-",5.739238,0,4.0237,0,3.97163,0.025711]
["MA0542","R","arCOG01759","COG1259","Bifunctional DNase/RNase",-0.792909,5.7E-005,-0.787798,0.000444,-0.544706,0.048932]
["MA0587","J","arCOG04302","COG0008","Glutamyl- or glutaminyl-tRNA synthetase",1.118509,0.001838,0.914693,0.004915,0.774666,0.055162]
["MA0596","J","arCOG04242","COG0102","Ribosomal protein L13",2.359066,2.3E-005,1.525041,0.000277,1.631876,0.027687]
["MA0597","J","arCOG04243","COG0103","Ribosomal protein S9",2.22443,0.000178,1.316117,0.003631,1.537024,0.027687]
["MA0599","K","arCOG01268","COG1758","DNA-directed RNA polymerase, subunit K/omega",2.264167,1.2E-005,1.531224,0.000155,1.567965,0.025711]
["MA0601","R","arCOG01728","COG1355","Predicted class III extradiol dioxygenase, MEMO1 family",1.49753,0.001126,1.069421,0.0087,1.04286,0.038419]
["MA0609","J","arCOG02466","COG3277","rRNA processing protein Gar1",1.242043,0.000659,0.986602,0.005948,0.858157,0.048314]
["MA0645","J","arCOG04108","COG2051","Ribosomal protein S27E",2.775367,2.4E-005,1.518858,0.000964,1.931054,0.025711]
["MA0646","J","arCOG04109","COG1631","Ribosomal protein L44E",2.917324,1E-006,1.794567,2.3E-005,2.024964,0.025711]
["MA0661","C","arCOG06546","COG4659","Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit",-1.494383,7E-006,-1.30186,0.000248,-1.045618,0.025711]
["MA0662","C","arCOG03955","COG4660","Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit",-1.121285,0.000278,-1.012483,0.003118,-0.787561,0.034045]
["MA0663","C","arCOG03954","COG4657","Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit",-1.192729,2.5E-005,-1.087265,0.000745,-0.836983,0.027687]
["MA0671","J","arCOG00187","COG1245","Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains",2.140366,0,1.363275,0.002034,1.480546,0.027687]
["MA0710","-","-","-","-",-1.523627,0.00055,-1.228222,0.005008,-1.051779,0.027687]
["MA0755","MR","arCOG07805","COG3049","Penicillin V acylase or related amidase, Ntn superfamily",-1.192245,0,-1.160349,0,-0.823951,0.031752]
["MA0832","C","arCOG00097","COG2218","Formylmethanofuran dehydrogenase subunit C",2.600034,2.8E-005,1.507695,0.000775,1.8201,0.028197]
["MA0833","C","arCOG04461","COG1229","Formylmethanofuran dehydrogenase subunit A",2.507795,1E-005,1.647789,6.9E-005,1.745643,0.029257]
["MA0834","C","arCOG01498","COG1029","Formylmethanofuran dehydrogenase subunit B",2.065215,5.6E-005,1.431735,0.000458,1.436633,0.028197]
["MA0835","C","arCOG02674","COG1153","Formylmethanofuran dehydrogenase subunit D",1.963359,3E-006,1.479385,4.7E-005,1.369804,0.027687]
["MA0887","P","arCOG00213","COG0226","ABC-type phosphate transport system, periplasmic component",-1.967129,0,-1.765471,0,-1.381267,0.025711]
["MA0901","R","arCOG04466","COG0733","Na+-dependent transporter, SNF family",0.729186,0.001125,0.651543,0.005008,0.497824,0.053849]
["MA0923","J","arCOG04154","COG2007","Ribosomal protein S8E",2.742669,1E-006,1.83016,6E-006,1.898581,0.025711]
["MA0949","J","arCOG04185","COG0184","Ribosomal protein S15P/S13E",2.375282,1.8E-005,1.521489,0.000296,1.645975,0.025711]
["MA0959","H","arCOG04459","COG0379","Quinolinate synthase",0.966862,0.000379,0.827668,0.002882,0.672719,0.059371]
["MA0964","-","-","-","-",-1.095701,1E-006,-1.050989,4E-005,-0.767492,0.037568]
["MA1011","C","arCOG01979","COG1456","CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein)",-2.604877,0,-1.959615,3E-006,-1.81175,0.049542]
["MA1012","C","arCOG01980","COG2069","CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein)",-2.929387,0,-2.31958,0,-2.037717,0.048314]
["MA1013","O","arCOG00587","COG3640","CO dehydrogenase nickel-insertion accessory protein CooC1",-2.221587,0,-1.726273,2.7E-005,-1.548966,0.04786]
["MA1087","J","arCOG04091","COG0096","Ribosomal protein S8",1.887389,3.1E-005,1.401281,0.000191,1.30126,0.025711]
["MA1108","J","arCOG01722","COG0099","Ribosomal protein S13",2.123906,0.000148,1.326065,0.002172,1.474849,0.038267]
["MA1110","J","arCOG04240","COG0100","Ribosomal protein S11",1.887626,0.000289,1.239173,0.003631,1.307987,0.027687]
["MA1140","O","arCOG04427","COG0298","Hydrogenase maturation factor",-0.688189,0.001248,-0.689679,0.006441,-0.4679,0.052598]
["MA1141","C","arCOG02474","COG1740","Ni,Fe-hydrogenase I small subunit",1.575682,0.000271,1.19935,0.001059,1.093624,0.037568]
["MA1143","C","arCOG05636","COG2864","Cytochrome b subunit of formate dehydrogenase",1.209159,5.5E-005,1.001592,0.000854,0.834903,0.037568]
["MA1167","FE","arCOG00067","COG0462","Phosphoribosylpyrophosphate synthetase",1.028912,1.5E-005,0.905556,0.000259,0.714195,0.054278]
["MA1255","J","arCOG01758","COG0051","Ribosomal protein S10",2.108484,0.000182,1.2605,0.004738,1.458012,0.025711]
["MA1326","P","arCOG07228","COG2608","Copper chaperone CopZ",-0.915818,5E-006,-0.899004,0.0001,-0.626655,0.037568]
["MA1352","-","-","-","-",2.222598,5.9E-005,1.456195,0.000694,1.548371,0.025711]
["MA1364","R","-","COG4783","Putative Zn-dependent protease, contains TPR repeats",-0.998482,1E-005,-0.962062,0.000132,-0.705416,0.048375]
["MA1393","E","arCOG01698","COG0065","Homoaconitase/3-isopropylmalate dehydratase large subunit",1.410853,0.001105,1.042198,0.007227,0.982386,0.043172]
["MA1431","O","arCOG02816","COG0225","Peptide methionine sulfoxide reductase MsrA",-0.621498,0.001177,-0.632216,0.003415,-0.42874,0.051875]
["MA1432","R","arCOG04702","COG1881","Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family",-1.202133,0,-1.156203,3E-006,-0.835397,0.025711]
["MA1446","J","arCOG04129","COG2139","Ribosomal protein L21E",2.078814,5.2E-005,1.211876,0.009702,1.43986,0.026741]
["MA1454","C","arCOG02920","COG3794","Plastocyanin",-0.861334,0.000445,-0.821262,0.004234,-0.585464,0.035324]
["MA1458","R","arCOG01690","COG1719","Predicted hydrocarbon binding protein, contains 4VR domain",1.240174,9.2E-005,1.027223,0.001327,0.863644,0.054135]
["MA1471","J","arCOG01988","COG2092","Translation elongation factor EF-1beta",1.996199,3.2E-005,1.216577,0.008606,1.390714,0.027687]
["MA1472","R","arCOG01989","COG2888","Predicted RNA-binding protein involved in translation, contains  Zn-ribbon domain, DUF1610 family",2.017714,2E-006,1.35106,0.001654,1.409137,0.027687]
["MA1477","O","arCOG04772","COG0576","Molecular chaperone GrpE (heat shock protein)",2.519978,4.7E-005,1.476807,0.001122,1.750949,0.025711]
["MA1490","H","arCOG00657","COG1060","2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)",1.261027,0.001644,0.965202,0.006763,0.876053,0.049937]
["MA1495","C","arCOG01557","COG0838","NADH:ubiquinone oxidoreductase subunit 3 (chain A)",2.217763,1E-006,1.624144,9E-006,1.548488,0.025711]
["MA1496","C","arCOG01554","COG0377","NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase",2.418233,7E-006,1.559765,0.000148,1.683275,0.025711]
["MA1497","C","arCOG01551","COG0852","NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)",3.114625,0,2.072104,0,2.161766,0.025711]
["MA1498","C","arCOG01548","COG0649","NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)",2.36828,9.9E-005,1.334236,0.003322,1.650754,0.027687]
["MA1501","C","arCOG08081","COG0839","NADH:ubiquinone oxidoreductase subunit 6 (chain J)",1.465544,3.2E-005,1.071218,0.008606,1.01433,0.048932]
["MA1503","C","arCOG08082","COG0713","NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)",2.089085,4E-006,1.251018,0.006228,1.450145,0.027687]
["MA1504","CP","arCOG01542","COG1009","NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit",1.831261,0.000468,1.225598,0.003631,1.276504,0.035346]
["MA1506","C","arCOG01540","COG1007","NADH:ubiquinone oxidoreductase subunit 2 (chain N)",1.979147,0.000431,1.226789,0.006322,1.377175,0.02866]
["MA1568","-","-","-","-",-1.234648,1.8E-005,-1.159098,3.1E-005,-0.8633,0.055697]
["MA1615","H","arCOG03325","COG0407","Uroporphyrinogen-III decarboxylase",-1.069021,2E-006,-1.030291,6.1E-005,-0.751211,0.034861]
["MA1616","-","-","-","-",-2.527978,0,-2.144759,0,-1.762521,0.028197]
["MA1617","C","arCOG02032","COG5012","Methanogenic corrinoid protein MtbC1",-2.469607,0,-2.065793,0,-1.724159,0.025711]
["MA1632","P","arCOG04888","COG2710","Nitrogenase molybdenum-iron protein, alpha and beta chains",-0.787547,0,-0.81536,0,-0.544881,0.048375]
["MA1633","P","arCOG00590","COG1348","Nitrogenase subunit NifH, an ATPase",-1.03366,0,-1.039906,0,-0.71182,0.034793]
["MA1682","O","arCOG05154","COG0459","Chaperonin GroEL (HSP60 family)",2.021109,0.000766,1.210858,0.008627,1.403464,0.042748]
["MA1690","-","-","-","-",-1.429701,0,-1.377306,0,-1.004178,0.035346]
["MA1735","C","arCOG00853","COG0281","Malic enzyme",-0.984741,5E-006,-0.967511,5.4E-005,-0.674906,0.048314]
["MA1775","J","arCOG04208","COG1997","Ribosomal protein L37AE/L43A",2.111749,7.3E-005,1.445686,0.000491,1.455672,0.025711]
["MA1783","J","arCOG01042","COG1325","Exosome subunit, RNA binding protein with dsRBD fold",1.962274,0,1.650686,0,1.358993,0.025711]
["MA1784","J","arCOG04209","COG1632","Ribosomal protein L15E",2.399824,0.000141,1.378524,0.002579,1.666608,0.035104]
["MA1851","-","-","-","-",-0.775976,9.7E-005,-0.774653,0.000517,-0.536845,0.048932]
["MA1964","F","arCOG04462","COG1828","Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component",1.503958,1E-006,1.271857,1.2E-005,1.038518,0.033131]
["MA2055","K","arCOG00732","COG1846","DNA-binding transcriptional regulator, MarR family",-1.118661,3.6E-005,-1.035318,0.000872,-0.787528,0.035104]
["MA2150","PH","arCOG00198","COG1120","ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component",-0.708534,9E-006,-0.728431,1E-005,-0.488225,0.054278]
["MA2152","H","arCOG01779","COG2226","Ubiquinone/menaquinone biosynthesis C-methylase UbiE",-0.911161,1E-006,-0.91101,1.2E-005,-0.626683,0.040373]
["MA2211","K","arCOG00732","COG1846","DNA-binding transcriptional regulator, MarR family",-0.621349,0.000226,-0.640346,0.000896,-0.432454,0.059972]
["MA2212","K","arCOG02038","COG1378","Sugar-specific transcriptional regulator TrmB",-0.884214,0.000122,-0.857021,0.001963,-0.616941,0.060654]
["MA2249","O","arCOG03580","COG2020","Protein-S-isoprenylcysteine O-methyltransferase Ste14",-0.627172,0.000101,-0.648864,0.000191,-0.432867,0.062388]
["MA2257","-","-","-","-",1.227653,0.000629,0.977398,0.003631,0.855669,0.048375]
["MA2267","-","-","-","-",-1.106487,0,-1.069765,5E-006,-0.764062,0.035346]
["MA2278","R","arCOG02935","COG1741","Redox-sensitive bicupin YhaK, pirin superfamily",-0.551328,0.001158,-0.571885,0.002522,-0.377575,0.056087]
["MA2296","-","-","-","-",-0.796854,0.001108,-0.778365,0.002442,-0.547425,0.048314]
["MA2308","R","arCOG02239","COG1342","Predicted DNA-binding protein, UPF0251 family",-0.627971,3.9E-005,-0.654403,1.4E-005,-0.43291,0.056907]
["MA2314","-","-","-","-",-0.632862,0.001391,-0.63696,0.0087,-0.432077,0.055697]
["MA2409","O","arCOG01311","COG0616","Periplasmic serine protease, ClpP class",-0.68821,0.000401,-0.696875,0.001262,-0.474517,0.059972]
["MA2424","C","arCOG02032","COG5012","Methanogenic corrinoid protein MtbC1",-0.705524,0.000103,-0.719572,0.000252,-0.486235,0.053849]
["MA2433","C","arCOG06774","COG0224","FoF1-type ATP synthase, gamma subunit",-0.555072,0.000483,-0.578832,0.00116,-0.383681,0.060654]
["MA2435","C","arCOG06775","COG0711","FoF1-type ATP synthase, membrane subunit b or b'",-0.940746,0,-0.936833,4E-006,-0.653865,0.035104]
["MA2440","C","arCOG06780","COG0355","FoF1-type ATP synthase, epsilon subunit",-0.648385,0.000666,-0.653697,0.005272,-0.447523,0.052065]
["MA2485","J","arCOG00109","COG2890","Methylase of polypeptide chain release factors",-0.721104,0.000357,-0.719155,0.003373,-0.493599,0.04786]
["MA2508","J","arCOG04733","COG2042","Ribosome biogenesis protein Tsr3 (rRNA maturation)",-0.625806,0.000998,-0.639553,0.005487,-0.426492,0.052065]
["MA2536","R","arCOG01849","COG0663","Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily",-2.340384,0,-2.232141,0,-1.6335,0.025711]
["MA2582","L","arCOG01247","COG4974","Site-specific recombinase XerD",-0.632435,0.000547,-0.64624,0.000752,-0.439402,0.061403]
["MA2592","-","-","-","-",-0.731201,0.00052,-0.717759,0.004595,-0.505421,0.052065]
["MA2604","-","-","-","-",-0.772166,2.3E-005,-0.777995,5.4E-005,-0.534915,0.055162]
["MA2850","R","arCOG01359","COG1031","Radical SAM superfamily enzyme with C-terminal helix-hairpin-helix motif",-0.75109,3.6E-005,-0.762927,5.7E-005,-0.515173,0.054409]
["MA2860","C","arCOG01252","COG1012","Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase",-0.755655,9.5E-005,-0.764147,0.000133,-0.519349,0.054278]
["MA2923","-","-","-","-",-0.857231,2.3E-005,-0.841421,0.000277,-0.605279,0.052729]
["MA2925","O","arCOG06268","COG1858","Cytochrome c peroxidase",-0.993856,0,-0.989885,0,-0.696414,0.036656]
["MA2964","-","-","-","-",-1.820228,4E-006,-1.511179,0.000138,-1.27095,0.025711]
["MA2982","-","-","-","-",-1.288022,1E-006,-1.202587,2.1E-005,-0.899152,0.029257]
["MA2985","-","-","-","-",-1.600912,6E-006,-1.39555,9.5E-005,-1.112337,0.035104]
["MA3044","J","arCOG00122","COG2265","tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family",-0.803616,2E-006,-0.822435,0,-0.554011,0.053736]
["MA3130","K","arCOG04377","COG4738","Predicted transcriptional regulator",3.107095,0,1.893128,3E-006,2.166787,0.025711]
["MA3139","A","arCOG05052","COG4085","DNA/RNA endonuclease YhcR, contains UshA esterase domain",-0.666346,0.000583,-0.672661,0.00508,-0.459712,0.054278]
["MA3171","M","arCOG03228","COG1136","ABC-type lipoprotein export system, ATPase component",-0.709176,4.1E-005,-0.724277,0.000115,-0.489476,0.053736]
["MA3194","J","arCOG04126","COG2126","Ribosomal protein L37E",2.712503,0,1.55512,0.000862,1.874648,0.025711]
["MA3258","-","-","-","-",-0.744812,5.8E-005,-0.753181,0.000359,-0.50727,0.052729]
["MA3263","R","arCOG03636","COG1380","Putative effector of murein hydrolase LrgA, UPF0299 family",0.986586,0,0.911353,0,0.685775,0.055697]
["MA3277","-","-","-","-",-0.83911,0,-0.850068,1E-006,-0.580593,0.048375]
["MA3382","E","arCOG01909","COG0174","Glutamine synthetase",2.456792,0.00055,1.266986,0.008618,1.712314,0.054278]
["MA3437","E","arCOG04452","COG1296","Predicted branched-chain amino acid permease (azaleucine resistance)",0.961994,8E-006,0.871053,1.6E-005,0.665299,0.054278]
["MA3522","F","arCOG02825","COG0299","Folate-dependent phosphoribosylglycinamide formyltransferase PurN",1.34749,0,1.20764,0,0.935074,0.033131]
["MA3576","-","-","-","-",0.875973,2.2E-005,0.788343,0.00012,0.602134,0.054278]
["MA3606","C","arCOG05260","COG0282","Acetate kinase",-2.70082,0,-2.009643,2E-006,-1.880657,0.055162]
["MA3607","C","arCOG00855","COG0280","Phosphotransacetylase",-1.720889,0.000195,-1.306404,0.003481,-1.205864,0.055697]
["MA3611","HR","arCOG07416","COG0596","Pimeloyl-ACP methyl ester carboxylesterase",-0.835547,0,-0.847944,4E-006,-0.576839,0.042748]
["MA3631","H","arCOG05434","COG2138","Sirohydrochlorin ferrochelatase",2.018966,5E-006,1.487282,6.6E-005,1.399992,0.025711]
["MA3667","V","arCOG04929","COG1857","CRISPR/Cas system-associated protein Cas7,  RAMP superfamily",-1.412825,0,-1.368451,0,-0.988883,0.038267]
["MA3696","J","arCOG04183","COG1998","Ribosomal protein S27AE",1.355874,8E-006,1.120379,0.000277,0.941089,0.055697]
["MA3733","HR","arCOG02410","COG2141","Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)",3.279427,4E-006,1.675629,0.000176,2.272313,0.029257]
["MA3739","-","-","-","-",-1.051894,0.000501,-0.990881,0.001711,-0.735121,0.052065]
["MA3740","C","arCOG00510","COG0655","Multimeric flavodoxin WrbA",-0.767799,0.001663,-0.748638,0.0087,-0.535305,0.036131]
["MA3791","E","arCOG00811","COG0440","Acetolactate synthase, small subunit",1.847066,0.000462,1.155368,0.008555,1.279341,0.033131]
["MA3792","EH","arCOG01614","COG0028","Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme",1.750621,0.000881,1.193793,0.004915,1.213751,0.052065]
["MA3793","E","arCOG02093","COG0119","Isopropylmalate/homocitrate/citramalate synthases",2.150691,6.8E-005,1.46417,0.000324,1.491417,0.038267]
["MA3811","-","-","-","-",-0.904624,0.00019,-0.869429,0.001621,-0.624142,0.054135]
["MA3839","-","-","-","-",0.860974,5E-005,0.765846,0.000896,0.589804,0.055697]
["MA3860","C","arCOG02428","COG1152","CO dehydrogenase/acetyl-CoA synthase alpha subunit",-4.099756,0,-3.07342,0,-2.845756,0.056907]
["MA3861","C","arCOG04408","COG1880","CO dehydrogenase/acetyl-CoA synthase epsilon subunit",-3.695176,0,-2.690505,0,-2.569865,0.03508]
["MA3862","C","arCOG04360","COG1614","CO dehydrogenase/acetyl-CoA synthase beta subunit",-4.053371,0,-2.816907,0,-2.812224,0.053849]
["MA3863","O","arCOG00587","COG3640","CO dehydrogenase nickel-insertion accessory protein CooC1",-2.711123,0,-2.07688,0,-1.888016,0.04786]
["MA3864","C","arCOG01980","COG2069","CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein)",-3.188315,0,-2.46307,0,-2.217553,0.04786]
["MA3865","C","arCOG01979","COG1456","CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein)",-2.779533,0,-2.092934,0,-1.933176,0.048375]
["MA3916","TE","arCOG02308","COG0347","Nitrogen regulatory protein PII",1.743134,7E-005,1.225353,0.004234,1.22415,0.035346]
["MA3917","P","arCOG04397","COG0004","Ammonia channel protein AmtB",1.323643,0.000306,1.08716,0.001557,0.928526,0.052065]
["MA3930","P","arCOG04233","COG0614","ABC-type Fe3+-hydroxamate transport system, periplasmic component",-0.639972,2.5E-005,-0.670489,3E-006,-0.44654,0.058706]
["MA3931","P","arCOG04233","COG0614","ABC-type Fe3+-hydroxamate transport system, periplasmic component",-0.950947,3E-006,-0.94313,8.1E-005,-0.663621,0.048375]
["MA3932","H","arCOG00977","COG2242","Precorrin-6B methylase 2",-1.081144,5E-006,-1.049537,3.2E-005,-0.750592,0.036271]
["MA4008","C","arCOG03176","COG1584","Succinate-acetate transporter protein",-0.732055,3E-006,-0.753205,2E-006,-0.512821,0.061273]
["MA4043","R","arCOG01289","COG1545","Uncharacterized OB-fold protein, contains Zn-ribbon domain",1.368605,0.000343,1.028736,0.004995,0.953256,0.048314]
["MA4117","J","arCOG01344","COG2238","Ribosomal protein S19E (S16A)",2.528253,7.2E-005,1.418962,0.002116,1.753822,0.025711]
["MA4120","S","arCOG15092","COG2034","Uncharacterized membrane protein",1.03786,4E-006,0.93321,5.9E-005,0.718338,0.052065]
["MA4131","-","-","-","-",0.662407,0.001116,0.59366,0.003073,0.450119,0.061332]
["MA4194","R","arCOG04073","COG1149","MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain",4.771552,0,3.274924,0,3.311585,0]
["MA4217","E","arCOG00095","COG0067","Glutamate synthase domain 1",1.845522,0.000647,1.17209,0.008177,1.288999,0.044059]
["MA4241","R","arCOG04073","COG1149","MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain",1.511713,0.000813,1.132292,0.003838,1.046633,0.035104]
["MA4242","R","arCOG04073","COG1149","MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain",2.119863,0.000611,1.254552,0.00746,1.470111,0.035161]
["MA4243","O","arCOG02734","COG1433","Predicted Fe-Mo cluster-binding protein, NifX family",1.732274,0.000212,1.277913,0.001123,1.208174,0.033131]
["MA4244","O","arCOG02734","COG1433","Predicted Fe-Mo cluster-binding protein, NifX family",2.311746,0.000108,1.432905,0.00134,1.614398,0.02609]
["MA4245","R","arCOG02239","COG1342","Predicted DNA-binding protein, UPF0251 family",1.576497,7.9E-005,1.231891,0.000344,1.092653,0.028556]
["MA4265","CE","arCOG01163","COG0473","Isocitrate/isopropylmalate dehydrogenase",1.749994,0.000912,1.149095,0.008561,1.214317,0.048314]
["MA4272","U","arCOG02204","COG2443","Preprotein translocase subunit Sss1",1.440615,1.1E-005,1.181863,0.000166,0.993896,0.033131]
["MA4274","J","arCOG04372","COG0080","Ribosomal protein L11",1.988043,0.000335,1.289466,0.003366,1.368984,0.029731]
["MA4339","E","arCOG04546","COG1246","N-acetylglutamate synthase or related acetyltransferase, GNAT family",1.870844,1E-006,1.300083,0.002281,1.302209,0.027687]
["MA4379","H","arCOG03325","COG0407","Uroporphyrinogen-III decarboxylase",4.601999,0,2.154265,1E-006,3.196253,0.027687]
["MA4390","-","-","-","-",1.272584,5.8E-005,1.109262,0.000452,0.878319,0.042748]
["MA4391","C","arCOG02032","COG5012","Methanogenic corrinoid protein MtbC1",3.182405,0,2.420553,0,2.209357,0.025711]
["MA4392","-","-","-","-",2.380885,9E-006,1.855522,3E-006,1.657086,0.036131]
["MA4393","C","arCOG03176","COG1584","Succinate-acetate transporter protein",1.594836,1E-006,1.412174,1E-006,1.101688,0.027687]
["MA4413","O","arCOG05154","COG0459","Chaperonin GroEL (HSP60 family)",2.557261,0.000185,1.403001,0.002259,1.775681,0.052065]
["MA4429","E","arCOG05228","COG0560","Phosphoserine phosphatase",1.597614,0.000805,1.160834,0.004118,1.103582,0.042748]
["MA4430","C","arCOG04382","COG1927","F420-dependent methylenetetrahydromethanopterin dehydrogenase",3.698018,0,2.089109,0,2.568106,0.027687]
["MA4436","S","arCOG04482","COG1891","Uncharacterized protein, UPF0264 family",1.584727,6.7E-005,1.256973,0.000277,1.10019,0.033131]
["MA4512","R","arCOG04916","COG3393","Predicted acetyltransferase, GNAT family",0.94112,0.00038,0.824317,0.001996,0.646954,0.052205]
["MA4517","H","arCOG04301","COG1469","GTP cyclohydrolase FolE2",1.614069,0.000663,1.169358,0.003482,1.12418,0.052065]
["MA4525","R","arCOG00126","COG0388","Predicted amidohydrolase",0.869911,7.2E-005,0.771419,0.000862,0.59817,0.053849]
["MA4567","P","arCOG04878","COG2212","Multisubunit Na+/H+ antiporter, MnhF subunit",-1.483277,0,-1.434213,0,-1.039019,0.026663]
["MA4568","P","arCOG03099","COG1863","Multisubunit Na+/H+ antiporter, MnhE subunit",-2.015856,0,-1.808507,0,-1.400603,0.025711]
["MA4569","CP","arCOG01541","COG0651","Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit",-1.803712,0,-1.634323,0,-1.262031,0.059734]
["MA4572","CP","arCOG01542","COG1009","NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit",-2.035489,0,-1.734144,0,-1.42436,0.04786]
["MA4590","F","arCOG00087","COG0518","GMP synthase - Glutamine amidotransferase domain",1.176841,5.6E-005,0.993498,0.000672,0.821599,0.048932]
["MA4608","C","arCOG00104","COG1795","Formaldehyde-activating enzyme nesessary for methanogenesis",1.943046,0.000162,1.355239,0.001148,1.345383,0.035324]
["MA4634","S","arCOG02254","COG1745","Uncharacterized protein",-2.416382,0,-1.858313,4E-006,-1.694924,0.025711]
["MA4659","R","arCOG01043","COG1931","Predicted RNA binding protein with dsRBD fold, UPF0201 family",1.031677,1.1E-005,0.905519,0.000228,0.711541,0.052797]
["MA4669","R","arCOG04946","COG3324","Predicted enzyme related to lactoylglutathione lyase",-0.678357,0.001362,-0.672361,0.009592,-0.463388,0.055697]
["MAt4685","-","-","-","-",2.279346,3E-006,1.716935,8E-006,1.577796,0.034045]
["MAt4690","-","-","-","-",2.757098,0,1.785428,2.4E-005,1.905104,0.025711]
["MAt4700","-","-","-","-",1.96453,7E-006,1.323038,0.002376,1.3593,0.048375]
["MAt4704","-","-","-","-",2.69445,1E-006,1.688355,0.000175,1.875008,0.028197]
["MAt4705","-","-","-","-",2.299192,0,1.822937,0,1.583643,0.027687]
["MAt4708","-","-","-","-",1.73174,4.9E-005,1.42763,7.2E-005,1.193014,0.035324]
["MAt4717","-","-","-","-",1.835196,1E-006,1.394021,0.000549,1.269551,0.033131]
["MAt4728","-","-","-","-",2.093742,1.9E-005,1.256933,0.0087,1.440988,0.027687]
["MAt4734","-","-","-","-",1.645907,6E-005,1.369561,0.000102,1.1381,0.052065]
["MAt4735","-","-","-","-",1.707161,1E-006,1.511949,0,1.185257,0.047259]

{"sheet":"MeOHvsTMA","index":2,"n_rows":212,"n_cols":11,"rows_kept":212,"cut":false,"hidden":false,"merged":[]}
["Gene","COGClass","arCOG","COG","Function","edgeR log2FC","edgeR p-value","DESeq2 log2FC","DESeq2 p-value","PoissonSeq log2FC","PoissonSeq p-value"]
["MA0018","T","-","COG3437","Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains",-1.071176,0,-0.919762,0.001322,-0.906918,8.1E-005]
["MA0073","-","-","-","-",-1.133746,0,0.562989,0.007148,-1.029868,0.000473]
["MA0117","S","arCOG04705","COG2098","Uncharacterized protein",0.672631,7.8E-005,0.601368,0.007148,0.30604,0.005602]
["MA0133","O","arCOG01841","COG0071","Molecular chaperone IbpA, HSP20 family",-1.453056,3.3E-005,-1.130369,0.007,-1.163412,2E-006]
["MA0141","V","arCOG04942","COG0841","Multidrug efflux pump subunit AcrB",-3.15131,0,-1.857188,0,-2.408093,0]
["MA0143","E","-","COG0833","Amino acid permease",-4.120148,0,-3.133267,0,-3.067049,0]
["MA0144","-","-","-","-",-6.680909,0,-5.796032,0,-4.796328,0]
["MA0145","C","arCOG02032","COG5012","Methanogenic corrinoid protein MtbC1",-6.730732,0,-5.354533,0,-4.857753,0]
["MA0146","H","arCOG03325","COG0407","Uroporphyrinogen-III decarboxylase",-4.246815,0,-3.199768,0,-3.104976,0]
["MA0150","S","arCOG02036","COG3894","Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain",-1.2518,0,-0.958974,0,-1.051433,9.6E-005]
["MA0152","I","arCOG00247","COG2084","3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase",-2.008465,0,-0.673269,0.003082,-1.630879,1.4E-005]
["MA0153","EF","arCOG01594","COG0458","Carbamoylphosphate synthase large subunit",-2.233138,0,-0.800319,0.003871,-1.789296,2E-006]
["MA0154","H","arCOG00659","COG0502","Biotin synthase or related enzyme",-2.593926,0,-1.318797,0,-2.029053,0]
["MA0155","J","arCOG00409","COG0017","Aspartyl/asparaginyl-tRNA synthetase",-2.018111,0,-1.325297,4.2E-005,-1.593066,0]
["MA0196","-","-","-","-",1.037941,0,0.610785,0.007102,0.597356,0.002464]
["MA0211","-","-","-","-",-0.649774,3.3E-005,-0.72602,0.000419,-0.59841,0.000285]
["MA0222","-","-","-","-",1.161012,0,0.501455,0.003509,0.717424,0.002314]
["MA0270","H","arCOG03380","COG4064","Tetrahydromethanopterin S-methyltransferase, subunit G",-1.68841,0.00087,-1.342238,0.006948,-1.281,0]
["MA0281","P","arCOG00164","COG0555","ABC-type sulfate transport system, permease component",0.886861,0,0.581463,0.006737,0.477397,0.006181]
["MA0304","C","arCOG00764","COG2191","Formylmethanofuran dehydrogenase subunit E",-1.769136,0,-1.555998,2.2E-005,-1.367879,0]
["MA0305","C","arCOG01543","COG1143","Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)",-1.878189,0,-1.731871,2E-006,-1.429218,0]
["MA0306","C","arCOG04461","COG1229","Formylmethanofuran dehydrogenase subunit A",-1.701286,2E-006,-1.493846,0.000173,-1.319624,2E-006]
["MA0307","C","arCOG00097","COG2218","Formylmethanofuran dehydrogenase subunit C",-1.987926,0,-1.846675,1E-006,-1.496688,0]
["MA0308","C","arCOG02674","COG1153","Formylmethanofuran dehydrogenase subunit D",-1.921765,0,-1.432606,8.4E-005,-1.503586,0]
["MA0309","C","arCOG01498","COG1029","Formylmethanofuran dehydrogenase subunit B",-2.011967,0,-1.845143,0,-1.528316,0]
["MA0355","-","-","-","-",1.185605,6E-006,1.0594,0.000386,0.659786,0.000602]
["MA0381","C","arCOG00764","COG2191","Formylmethanofuran dehydrogenase subunit E",-1.561881,1.2E-005,-1.258202,0.003063,-1.225596,0]
["MA0429","S","arCOG02701","COG1641","Uncharacterized conserved protein, DUF111 family",-1.006886,0,-0.789906,0.00226,-0.868478,0.000103]
["MA0455","-","-","-","-",5.690505,0,4.074231,0,3.779937,2E-006]
["MA0456","C","arCOG02032","COG5012","Methanogenic corrinoid protein MtbC1",6.134926,0,4.002294,0,4.128205,0]
["MA0457","-","-","-","-",6.033414,0,4.124476,0,4.057463,0]
["MA0527","C","arCOG02032","COG5012","Methanogenic corrinoid protein MtbC1",-8.295887,0,-7.266178,0,-5.913401,0]
["MA0528","H","arCOG03405","COG5598","Trimethylamine:corrinoid methyltransferase",-8.031969,0,-6.23614,0,-5.776844,0]
["MA0529","C","arCOG02032","COG5012","Methanogenic corrinoid protein MtbC1",-7.92314,0,-6.238636,0,-5.692521,0]
["MA0531","-","-","-","-",-6.814971,0,-5.500503,0,-4.92654,0]
["MA0532","-","-","-","-",-7.359559,0,-6.314441,0,-5.27445,0]
["MA0545","R","arCOG02680","COG1326","Uncharacterized archaeal Zn-finger protein",-0.811085,0.001797,-0.918165,0.008504,-0.689437,0.000103]
["MA0568","-","-","-","-",1.165442,0,0.668093,0.008996,0.688574,0.000393]
["MA0569","-","-","-","-",1.103534,0,0.453547,0.007042,0.679563,0.000522]
["MA0572","-","-","-","-",0.806594,5E-006,0.665458,0.00327,0.402506,0.00244]
["MA0582","H","arCOG04299","COG0181","Porphobilinogen deaminase",-1.617907,0,-1.041635,0.00743,-1.299568,0]
["MA0583","F","arCOG00603","COG0167","Dihydroorotate dehydrogenase",-1.410287,0,-0.78218,0.006595,-1.171505,1.7E-005]
["MA0630","O","arCOG05153","COG0234","Co-chaperonin GroES (HSP10)",-1.810971,3E-005,-1.232375,0.009194,-1.406595,0]
["MA0650","-","-","-","-",0.891885,0,0.516602,0.001176,0.488783,0.003307]
["MA0675","I","arCOG01591","COG4770","Acetyl/propionyl-CoA carboxylase, alpha subunit",-1.667748,1E-006,-1.240147,0.001952,-1.318315,0]
["MA0679","D","arCOG00369","COG1196","Chromosome segregation ATPase",-1.27033,0.000192,-1.240897,0.00227,-1.003907,8E-006]
["MA0689","S","arCOG02078","COG1852","Uncharacterized protein",-0.825672,0,0.576684,0.001734,-0.807323,0.00161]
["MA0710","-","-","-","-",-1.667364,2E-005,-1.413981,0.001322,-1.286401,0]
["MA0712","-","-","-","-",-0.930963,0,-0.719492,0.003517,-0.813756,9.7E-005]
["MA0740","-","-","-","-",1.117034,0,0.622774,8.4E-005,0.66279,0.00062]
["MA0752","R","arCOG05159","COG1750","Predicted archaeal serine protease, S18 family",-1.199689,0,-0.894257,0.001227,-1.00813,5.5E-005]
["MA0779","H","arCOG03325","COG0407","Uroporphyrinogen-III decarboxylase",-0.905747,0,-0.548205,0.005256,-0.811358,0.000131]
["MA0783","U","arCOG03382","COG0823","Periplasmic component of the Tol biopolymer transport system",-1.118956,0.000277,-1.037013,0.005041,-0.927318,8E-005]
["MA0786","-","-","-","-",1.666613,0,0.936268,0.001438,1.067441,0.000126]
["MA0799","S","arCOG00901","COG0392","Uncharacterized membrane protein YbhN, UPF0104 family",1.290065,0,0.727241,0.001438,0.786219,0.00044]
["MA0825","-","-","-","-",-2.390479,0,0.792128,0,-1.922645,1.6E-005]
["MA0831","X","arCOG03506","COG3293","Transposase",1.087362,0,0.531956,0.00052,0.652808,0.002283]
["MA0858","EQ","arCOG01517","COG0145","N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit",-4.190542,0,-1.609145,0,-3.16289,0]
["MA0863","T","arCOG02369","COG0642","Signal transduction histidine kinase",-1.195965,1.3E-005,-0.888435,0.004794,-1.000061,6.4E-005]
["MA0864","T","arCOG02367","COG2202","PAS domain",-0.972743,8E-006,-0.874236,0.003314,-0.82902,7.9E-005]
["MA0881","EP","arCOG00751","COG0601","ABC-type dipeptide/oligopeptide/nickel transport system, permease component",1.016705,0,0.607668,0.005804,0.576509,0.001351]
["MA0901","R","arCOG04466","COG0733","Na+-dependent transporter, SNF family",1.02333,0,0.750578,0.001485,0.563607,0.004595]
["MA0936","O","arCOG01716","COG0719","Fe-S cluster assembly scaffold protein SufB",-1.457222,0,-1.046308,0.00208,-1.183196,4E-006]
["MA0942","E","arCOG04273","COG0079","Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase",-1.525522,0,-1.083424,0.00226,-1.229394,2E-006]
["MA0962","H","arCOG01678","COG1812","Archaeal S-adenosylmethionine synthetase",-0.719228,2.4E-005,-0.677715,0.001889,-0.659727,0.000242]
["MA0963","R","arCOG00720","COG1458","Predicted DNA-binding protein containing PIN domain, UPF0278 family",-0.562063,0.001603,-0.696096,0.00137,-0.533954,0.000407]
["MA0975","C","arCOG01549","COG3259","Coenzyme F420-reducing hydrogenase, alpha subunit",-1.111488,0,-0.783999,0.002569,-0.948041,4.9E-005]
["MA1012","C","arCOG01980","COG2069","CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein)",-1.862889,1E-006,-1.216059,0.005741,-1.475275,0]
["MA1023","C","arCOG01600","COG1014","Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit",-1.036738,4E-005,-0.904487,0.008504,-0.871468,3.2E-005]
["MA1139","O","arCOG04428","COG0409","Hydrogenase maturation factor",-1.167791,0,-0.710445,0.003306,-0.994687,5E-005]
["MA1188","-","-","-","-",0.85802,0,0.755003,0.000136,0.442274,0.003235]
["MA1276","FR","arCOG00700","COG0402","Cytosine/adenosine deaminase or related metal-dependent hydrolase",-1.363356,1E-005,-1.072799,0.004912,-1.106285,1.4E-005]
["MA1285","-","-","-","-",-0.71705,1.6E-005,-1.071171,1E-006,-0.617068,0.000282]
["MA1305","R","arCOG01206","COG1669","Predicted nucleotidyltransferase",1.327648,0,0.693812,0.00743,0.823461,0.000221]
["MA1318","E","arCOG01748","COG0165","Argininosuccinate lyase",-0.971584,1E-006,-0.698097,0.004384,-0.84942,0.00013]
["MA1332","-","-","-","-",1.065774,0,0.469203,0.005752,0.641165,0.001346]
["MA1381","R","arCOG00364","COG1100","GTPase SAR1 family domain",-1.186436,8.4E-005,-1.038793,0.006574,-0.977189,4.6E-005]
["MA1418","O","arCOG00185","COG1123","ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain",-1.030244,2.3E-005,-0.916383,0.002993,-0.877435,0.000112]
["MA1419","H","arCOG02252","COG0619","Energy-coupling factor transporter transmembrane protein EcfT",-1.699179,0,-1.422816,1E-006,-1.352464,0]
["MA1432","R","arCOG04702","COG1881","Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family",-0.866241,9E-006,-0.812306,0.002993,-0.75523,8.1E-005]
["MA1460","KT","arCOG04782","COG1842","Phage shock protein A",-1.513334,0.00013,-1.272608,0.004912,-1.176661,0]
["MA1490","H","arCOG00657","COG1060","2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)",-1.491086,1E-006,-0.942993,0.009927,-1.214902,1.7E-005]
["MA1588","K","arCOG08032","COG1522","DNA-binding transcriptional regulator, Lrp family",-1.005213,0,-0.777721,0.003064,-0.866452,8.6E-005]
["MA1615","H","arCOG03325","COG0407","Uroporphyrinogen-III decarboxylase",-1.260535,0,-0.756876,0.006824,-1.067076,5E-005]
["MA1654","R","arCOG00769","COG0693","Putative intracellular protease/amidase",-0.334194,0.008132,-0.495398,0.000882,-0.377759,0.003515]
["MA1668","M","arCOG03228","COG1136","ABC-type lipoprotein export system, ATPase component",-1.108745,0,-0.825668,0.00743,-0.936892,3.3E-005]
["MA1674","M","arCOG02313","COG4591","ABC-type transport system, involved in lipoprotein release, permease component",-0.999206,0,-0.702702,0.00226,-0.871941,0.000123]
["MA1683","G","arCOG01122","COG0120","Ribose 5-phosphate isomerase",-1.238072,0,-0.998737,0.00208,-1.02023,1.4E-005]
["MA1725","H","arCOG02622","COG1541","Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family",-1.247537,1E-006,-0.884253,0.009701,-1.039676,3.2E-005]
["MA1735","C","arCOG00853","COG0281","Malic enzyme",-0.746084,7.4E-005,-0.707734,0.006737,-0.682252,0.000324]
["MA1779","O","arCOG00970","COG0638","20S proteasome, alpha and beta subunits",-1.637249,7.7E-005,-1.226155,0.008095,-1.279754,0]
["MA1805","H","arCOG03221","COG4063","Tetrahydromethanopterin S-methyltransferase, subunit A",-1.20696,0,-0.712612,0.005256,-1.02245,2.9E-005]
["MA1818","H","arCOG01323","COG0054","6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)",-1.647189,0,-1.095635,0.003314,-1.320833,0]
["MA1940","-","-","-","-",-0.649274,1.4E-005,-0.52236,0.009772,-0.618519,0.000602]
["MA1977","H","arCOG01872","COG0746","Molybdopterin-guanine dinucleotide biosynthesis protein A",-0.62143,5E-006,-0.564537,0.002993,-0.596802,0.000459]
["MA1978","H","arCOG00534","COG0314","Molybdopterin synthase catalytic subunit",-1.017588,0,-0.938828,0.000567,-0.861428,7E-005]
["MA2004","J","arCOG00080","COG1189","Predicted rRNA methylase YqxC, contains S4 and FtsJ domains",-0.69966,0.000168,-0.698811,0.008537,-0.637186,0.000181]
["MA2011","R","arCOG04946","COG3324","Predicted enzyme related to lactoylglutathione lyase",-0.456372,0.002105,-0.680524,0.001049,-0.454889,0.001253]
["MA2032","P","arCOG00590","COG1348","Nitrogenase subunit NifH, an ATPase",-1.232615,0,-0.867146,0.006337,-1.029144,2.1E-005]
["MA2110","V","arCOG00189","COG1131","ABC-type multidrug transport system, ATPase component",-0.701944,5.1E-005,-0.773995,0.0008,-0.634648,0.000229]
["MA2193","UW","-","COG5010","Flp pilus assembly protein TadD, contains TPR repeats",-1.004822,0,-0.858024,0,-0.872875,0.000145]
["MA2304","HE","arCOG00083","COG1932","Phosphoserine aminotransferase",-0.73156,0.000109,-0.68363,0.00743,-0.664997,0.000186]
["MA2310","F","arCOG00693","COG1001","Adenine deaminase",-0.888364,2E-006,-0.697782,0.006412,-0.784465,0.000117]
["MA2430","S","arCOG04303","COG1634","Uncharacterized Rossmann fold enzyme",-1.23166,0,-0.71562,0.000804,-1.0489,5E-005]
["MA2435","C","arCOG06775","COG0711","FoF1-type ATP synthase, membrane subunit b or b'",-0.461404,0.002831,-0.621624,0.006482,-0.459738,0.000535]
["MA2495","C","arCOG00510","COG0655","Multimeric flavodoxin WrbA",-0.890128,2E-006,-0.763086,0.005379,-0.780692,0.000135]
["MA2517","R","arCOG04219","COG2433","Possible nuclease of RNase H fold, RuvC/YqgF family",-0.536877,0.000242,-0.479149,0.005741,-0.535395,0.000594]
["MA2533","H","arCOG01481","COG1488","Nicotinic acid phosphoribosyltransferase",-0.9858,0,-0.861274,2.2E-005,-0.849435,0.000128]
["MA2534","-","-","-","-",-1.566903,0.000166,-1.26382,0.007458,-1.241651,0]
["MA2561","T","arCOG02278","COG2203","GAF domain",-2.789239,0,-1.481992,0,-2.162219,0]
["MA2575","-","-","-","-",-0.945494,0,-0.684296,0.00754,-0.829649,0.000128]
["MA2717","O","arCOG02077","COG0822","NifU homolog involved in Fe-S cluster formation",-2.412613,0,-1.239515,0.00963,-1.85668,0]
["MA2746","K","arCOG02643","COG1309","DNA-binding transcriptional regulator, AcrR family",-0.557548,0.000149,-0.657906,0.000601,-0.543003,0.000822]
["MA2761","K","arCOG02643","COG1309","DNA-binding transcriptional regulator, AcrR family",-0.456648,0.006084,-0.915365,1.8E-005,-0.423896,0.001237]
["MA2858","-","-","-","-",1.056982,1.9E-005,0.803368,0.009194,0.58502,0.001257]
["MA2933","E","arCOG05706","COG1506","Dipeptidyl aminopeptidase/acylaminoacyl peptidase",-0.901425,0,-0.482171,0.008926,-0.813474,0.000212]
["MA2963","C","arCOG01503","COG0437","Fe-S-cluster-containing dehydrogenase component",-0.630188,1E-006,-0.533063,0.00076,-0.606101,0.000523]
["MA2964","-","-","-","-",-2.503678,0,-1.506301,0.000182,-1.93496,0]
["MA2972","-","-","-","-",-0.555901,0.005303,-0.696389,0.007458,-0.527028,0.000364]
["MA2985","-","-","-","-",-1.192569,0.00013,-1.157237,0.002404,-0.966195,3E-005]
["MA2986","EH","arCOG00086","COG0512","Anthranilate/para-aminobenzoate synthase component II",-1.853841,0,-1.457185,0.000125,-1.451302,0]
["MA2987","EH","arCOG02014","COG0147","Anthranilate/para-aminobenzoate synthases component I",-2.332266,0,-2.081226,1E-006,-1.718542,0]
["MA2988","E","arCOG01983","COG0135","Phosphoribosylanthranilate isomerase",-2.413886,0,-2.192603,0,-1.802792,0]
["MA2989","E","arCOG02012","COG0547","Anthranilate phosphoribosyltransferase",-2.416493,0,-2.143637,0,-1.789326,0]
["MA2990","E","arCOG01086","COG0159","Tryptophan synthase alpha chain",-1.87891,0,-1.891862,0,-1.419508,0]
["MA2991","E","arCOG01433","COG0133","Tryptophan synthase beta chain",-1.974438,0,-1.822096,5E-006,-1.480863,0]
["MA3024","G","arCOG00768","COG1109","Phosphomannomutase",-1.377667,2E-006,-1.051576,0.003968,-1.118916,2E-006]
["MA3033","H","arCOG00649","COG0007","Uroporphyrinogen-III methylase (siroheme synthase)",-1.33215,0,-0.991834,0.005741,-1.08875,2E-006]
["MA3132","-","-","-","-",1.030517,0,0.896473,4.7E-005,0.557589,0.000654]
["MA3167","C","arCOG02056","COG1251","NAD(P)H-nitrite reductase, large subunit",-0.879596,1.5E-005,-1.053288,0.000136,-0.741997,9.4E-005]
["MA3198","E","arCOG01432","COG1350","Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB)",-1.637775,1E-006,-1.413515,0.000215,-1.282003,0]
["MA3250","H","arCOG00107","COG1492","Cobyric acid synthase",-1.381811,0,-1.176774,5E-006,-1.123348,2.3E-005]
["MA3252","E","arCOG01035","COG2423","Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family",-0.728523,1.9E-005,-0.710566,0.001387,-0.66137,0.000213]
["MA3303","-","-","-","-",1.046027,1.3E-005,0.799155,0.008996,0.57546,0.000816]
["MA3344","G","arCOG01349","COG0483","Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family",-1.198612,1E-006,-1.003212,0.001517,-0.993268,4.2E-005]
["MA3407","J","arCOG01488","COG0590","tRNA(Arg) A34 adenosine deaminase TadA",-0.370243,0.007189,-0.529108,0.00539,-0.400107,0.0018]
["MA3553","P","arCOG04384","COG1930","ABC-type cobalt transport system, periplasmic component",-1.055376,0,-0.932074,1.3E-005,-0.8961,9.9E-005]
["MA3564","E","arCOG04413","COG1364","N-acetylglutamate synthase (N-acetylornithine aminotransferase)",-1.467579,3E-005,-1.091441,0.009487,-1.175782,0]
["MA3565","K","arCOG00610","COG2524","Predicted transcriptional regulator, contains C-terminal CBS domains",-1.184123,0.000177,-1.129827,0.003971,-0.956507,2.1E-005]
["MA3606","C","arCOG05260","COG0282","Acetate kinase",-1.885031,1.4E-005,-1.272885,0.006595,-1.479751,0]
["MA3611","HR","arCOG07416","COG0596","Pimeloyl-ACP methyl ester carboxylesterase",-0.382945,0.006414,-0.584097,0.004298,-0.409351,0.002026]
["MA3650","-","-","-","-",1.007312,0,0.506208,0.001438,0.590275,0.001624]
["MA3682","M","arCOG12808","COG0438","Glycosyltransferase involved in cell wall bisynthesis",-1.606298,4E-006,-1.124674,0.007301,-1.278945,2E-006]
["MA3736","R","arCOG02150","COG0599","Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family",-1.799651,4.6E-005,-1.308219,0.006234,-1.388704,0]
["MA3739","-","-","-","-",-1.730365,0,-1.160015,0.000215,-1.388505,2E-006]
["MA3741","C","arCOG01705","COG1036","Archaeal flavoprotein",-1.534793,0,-0.865748,0.009264,-1.258081,2E-006]
["MA3742","P","arCOG03349","COG1633","Rubrerythrin",-1.890017,0,-1.316716,0.003064,-1.473718,0]
["MA3743","C","arCOG00509","COG0426","Flavorubredoxin",-1.471386,0,-0.7226,0.006195,-1.222367,3.1E-005]
["MA3746","Q","arCOG03340","COG3527","Alpha-acetolactate decarboxylase",0.951841,0,0.818258,0.000104,0.50324,0.001019]
["MA3860","C","arCOG02428","COG1152","CO dehydrogenase/acetyl-CoA synthase alpha subunit",-1.68535,0.000172,-1.343631,0.003517,-1.324409,0]
["MA3862","C","arCOG04360","COG1614","CO dehydrogenase/acetyl-CoA synthase beta subunit",-1.833071,0.000201,-1.351173,0.005804,-1.423432,0]
["MA3864","C","arCOG01980","COG2069","CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein)",-1.816481,7E-006,-1.19355,0.007977,-1.441212,0]
["MA3884","D","arCOG02263","COG2450","Predicted archaeal cell division protein, SepF homolog, DUF552 family",-1.552645,0,-1.02461,0.007337,-1.251199,0]
["MA3889","G","arCOG04044","COG1830","Fructose-bisphosphate aldolase class Ia, DhnA family",-1.556663,3E-005,-1.166563,0.007535,-1.228566,0]
["MA3930","P","arCOG04233","COG0614","ABC-type Fe3+-hydroxamate transport system, periplasmic component",-0.53071,4.9E-005,-0.613803,4.2E-005,-0.524604,0.000705]
["MA3931","P","arCOG04233","COG0614","ABC-type Fe3+-hydroxamate transport system, periplasmic component",-1.268245,0,-1.139308,1E-006,-1.05085,7.8E-005]
["MA3932","H","arCOG00977","COG2242","Precorrin-6B methylase 2",-0.947915,5E-006,-1.026032,7E-005,-0.802948,0.000104]
["MA3933","PH","arCOG00198","COG1120","ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component",-0.603812,0.0013,-0.742692,0.006195,-0.562205,0.000241]
["MA3939","S","arCOG03333","COG4273","Uncharacterized protein, contains metal-binding DGC domain",-0.978846,0,-0.768181,2.2E-005,-0.854248,0.000198]
["MA3941","S","arCOG02712","COG0701","Uncharacterized membrane protein YraQ, UPF0718 family",0.995112,0,0.563961,2.2E-005,0.568568,0.002433]
["MA3980","-","-","-","-",1.6255,0,0.87607,0.006138,1.035976,0.000134]
["MA4044","TR","arCOG01723","COG1437","Adenylate cyclase class IV, CYTH domain (includes archaeal enzymes of unknown function)",-1.536837,0,-1.137037,0.000732,-1.232529,0]
["MA4056","-","-","-","-",1.267963,0,0.781187,0.003097,0.759082,0.000965]
["MA4068","O","arCOG00315","COG1225","Peroxiredoxin",-0.819047,0,-0.630465,0.000666,-0.744174,0.000219]
["MA4139","-","-","-","-",0.886078,0,0.581132,0.000215,0.479861,0.002563]
["MA4141","-","-","-","-",1.60076,0,0.969944,0.00226,0.997713,0.000104]
["MA4146","-","-","-","-",0.81712,4.4E-005,0.616767,0.000544,0.419554,0.005971]
["MA4148","I","arCOG03951","COG0671","Membrane-associated phospholipid phosphatase",1.149525,0,0.597399,0.008996,0.687066,0.000565]
["MA4175","C","arCOG04461","COG1229","Formylmethanofuran dehydrogenase subunit A",-0.854032,0.000179,-1.168838,1E-006,-0.719064,0.00025]
["MA4176","C","arCOG00097","COG2218","Formylmethanofuran dehydrogenase subunit C",-1.713772,0,-1.763263,0,-1.301495,0]
["MA4177","C","arCOG02674","COG1153","Formylmethanofuran dehydrogenase subunit D",-0.991054,0,-0.877143,0.000311,-0.854954,0.000103]
["MA4210","-","-","-","-",0.955675,0,0.466171,0.006423,0.547166,0.001373]
["MA4215","-","-","-","-",1.552298,0,0.911043,0.00058,0.977343,0.000371]
["MA4222","P","arCOG06512","COG3420","Nitrous oxidase accessory protein NosD, contains tandem CASH domains",1.100586,0,0.692187,0.005256,0.633731,0.002067]
["MA4250","EP","arCOG00751","COG0601","ABC-type dipeptide/oligopeptide/nickel transport system, permease component",1.079962,0,0.666255,0.000337,0.625577,0.001891]
["MA4256","-","-","-","-",0.686343,8E-006,0.777789,1E-005,0.302071,0.00461]
["MA4258","H","arCOG02247","COG2082","Precorrin isomerase",-1.632136,0,-1.036993,0.00283,-1.313008,0]
["MA4259","H","arCOG00647","COG1010","Precorrin-3B methylase",-1.704791,0,-1.175109,0.00226,-1.351334,0]
["MA4261","H","arCOG00645","COG2875","Precorrin-4 methylase",-1.725288,0,-1.046847,0.005324,-1.380996,0]
["MA4262","H","arCOG00648","COG2243","Precorrin-2 methylase",-1.544769,0,-1.049041,0.002972,-1.249932,2E-006]
["MA4282","-","-","-","-",1.335572,0,0.700042,0.003063,0.830762,0.000285]
["MA4311","-","-","-","-",1.496328,0,0.894216,0.001322,0.928505,0.000149]
["MA4328","M","arCOG02470","COG2834","Outer membrane lipoprotein-sorting protein",-0.733871,0.000101,-0.640308,0.005835,-0.670897,0.000231]
["MA4329","H","arCOG02741","COG0422","Thiamine biosynthesis protein ThiC",-2.205726,1E-006,-1.413886,0.00226,-1.692908,0]
["MA4346","KT","arCOG03455","COG1983","Phage shock protein PspC (stress-responsive transcriptional regulator)",-0.946907,2E-006,-0.842455,0.002993,-0.814347,9.2E-005]
["MA4382","R","arCOG01234","COG0523","GTPase, G3E family",-1.209673,0,-0.720446,0.00743,-1.030713,0.000104]
["MA4391","C","arCOG02032","COG5012","Methanogenic corrinoid protein MtbC1",2.886156,0,2.32543,0,1.849298,0.000165]
["MA4392","-","-","-","-",2.390769,0,1.940549,1E-006,1.506236,0.000493]
["MA4393","C","arCOG03176","COG1584","Succinate-acetate transporter protein",2.10768,0,1.742127,0,1.319641,0.000141]
["MA4394","P","arCOG01480","COG0053","Divalent metal cation (Fe/Co/Zn/Cd) transporter",1.175566,0,0.510376,0.007301,0.728072,0.00066]
["MA4406","O","arCOG04236","COG0396","Fe-S cluster assembly ATPase SufC",-1.320457,2E-006,-1.03378,0.003314,-1.07762,1.6E-005]
["MA4445","-","-","-","-",1.221996,0,0.772222,0.005256,0.718044,0.000302]
["MA4455","R","arCOG01395","COG1817","Predicted glycosyltransferase",1.115351,0,0.521867,0.00208,0.674323,0.001868]
["MA4466","O","arCOG10178","COG1266","Membrane protease YdiL, CAAX protease family",0.873754,0,0.706572,0.000491,0.450472,0.005126]
["MA4475","-","-","-","-",1.497006,0,0.910832,0.00076,0.925837,0.000136]
["MA4494","-","-","-","-",1.117741,0,0.546451,0.006428,0.676449,0.001672]
["MA4498","-","-","-","-",1.035613,0,0.670572,0.006713,0.586167,0.001463]
["MA4499","-","-","-","-",1.093802,0,0.543105,0.005752,0.651139,0.001242]
["MA4505","NU","arCOG02298","COG1989","Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase",0.980568,0,0.601415,0.00137,0.553898,0.003487]
["MA4546","H","arCOG04857","COG4058","Methyl coenzyme M reductase, alpha subunit",-2.480303,2.6E-005,-1.364016,0.00661,-1.890237,0]
["MA4547","H","arCOG04858","COG4057","Methyl coenzyme M reductase, gamma subunit",-2.057212,0.000221,-1.453038,0.003097,-1.560144,0]
["MA4578","-","-","-","-",1.136431,0,0.606565,0.002569,0.678765,0.003098]
["MA4583","P","arCOG03159","COG0310","ABC-type Co2+ transport system, permease component",1.068207,0,0.615346,0.006713,0.623521,0.000749]
["MA4591","G","arCOG04044","COG1830","Fructose-bisphosphate aldolase class Ia, DhnA family",-1.257743,0.000189,-1.110468,0.006202,-1.010328,2.1E-005]
["MA4592","E","arCOG04353","COG1465","3-dehydroquinate synthase, class II",-1.450199,4.7E-005,-1.109007,0.009555,-1.156718,2E-006]
["MA4595","E","arCOG00256","COG0287","Prephenate dehydrogenase",-0.603729,0.003259,-0.701136,0.008949,-0.568042,0.000387]
["MA4601","E","arCOG01536","COG0747","ABC-type transport system, periplasmic component",-1.015749,0.000395,-0.971996,0.00345,-0.855455,0.000105]
["MA4602","C","arCOG00764","COG2191","Formylmethanofuran dehydrogenase subunit E",-0.862129,5.2E-005,-0.813245,0.004912,-0.755163,0.000135]
["MA4606","PH","arCOG00198","COG1120","ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component",1.057836,0,0.559053,0.008159,0.619907,0.00179]
["MA4651","K","arCOG00610","COG2524","Predicted transcriptional regulator, contains C-terminal CBS domains",-1.907064,7E-006,-1.397574,0.002294,-1.470084,0]
["MAt4734","-","-","-","-",1.732297,0,1.249143,0.000698,1.072314,0.000934]

{"sheet":"TMAvsAce","index":3,"n_rows":646,"n_cols":11,"rows_kept":646,"cut":false,"hidden":false,"merged":[]}
["Gene","COGClass","arCOG","COG","Function","edgeR log2FC","edgeR p-value","DESeq2 log2FC","DESeq2 p-value","PoissonSeq log2FC","PoissonSeq p-value"]
["MA0001","L","arCOG00468","COG1474","Cdc6-related protein, AAA superfamily ATPase",1.245989,0.0001,0.950078,0.002926,1.066447,0.000537]
["MA0006","E","arCOG00119","COG0076","Glutamate or tyrosine decarboxylase or a related PLP-dependent protein",1.212415,1.4E-005,0.751127,0.006194,1.062128,0.000798]
["MA0010","C","arCOG02695","COG2037","Formylmethanofuran:tetrahydromethanopterin formyltransferase",3.850426,0,2.096782,0,2.915144,0]
["MA0018","T","-","COG3437","Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains",1.020528,0.000177,0.813502,0.009167,0.898006,0.000952]
["MA0024","P","arCOG05372","COG1121","ABC-type Mn2+/Zn2+ transport system, ATPase component",1.236219,3E-006,0.917108,0.001107,1.065154,0.000547]
["MA0026","-","-","-","-",3.145806,0,1.457562,4.6E-005,2.448853,0]
["MA0031","C","arCOG01599","COG1013","Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit",3.21608,0,1.770647,5.7E-005,2.460325,6.9E-005]
["MA0032","C","arCOG01607","COG0674","Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit",3.242658,1E-006,1.817388,5.5E-005,2.46385,6.9E-005]
["MA0033","C","arCOG01605","COG1144","Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit",2.981112,1E-005,1.892947,3.1E-005,2.227536,0]
["MA0034","C","arCOG01600","COG1014","Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit",3.801929,0,1.911164,4E-006,2.890023,0]
["MA0043","J","arCOG00487","COG0018","Arginyl-tRNA synthetase",1.650082,0,0.907128,0.003227,1.379989,0.000261]
["MA0056","R","arCOG01641","COG3269","Predicted RNA-binding protein, contains TRAM domain",2.8806,3.4E-005,1.275931,0.006751,2.217991,0]
["MA0058","R","arCOG01641","COG3269","Predicted RNA-binding protein, contains TRAM domain",2.914873,7E-006,1.231253,0.009632,2.246066,0]
["MA0086","O","arCOG05154","COG0459","Chaperonin GroEL (HSP60 family)",4.378841,0,2.181763,1E-006,3.24481,6.9E-005]
["MA0092","S","arCOG04308","COG1698","Uncharacterized protein, UPF0147 family",2.99343,0,1.226896,0.009423,2.316054,0]
["MA0093","R","arCOG00578","COG1645","Uncharacterized Zn-finger containing protein, UPF0148 family",1.562233,8E-006,1.192423,0.000834,1.275444,0.000186]
["MA0097","J","arCOG00405","COG0423","Glycyl-tRNA synthetase (class II)",1.935246,1.1E-005,1.336521,0.000479,1.553371,0.000152]
["MA0104","L","arCOG02303","COG0496","Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE",1.634838,0,1.089554,5.8E-005,1.357112,0.000196]
["MA0105","H","arCOG00954","COG2896","Molybdenum cofactor biosynthesis enzyme MoaA",1.914741,0,0.996936,0.001125,1.571578,0.000152]
["MA0106","H","arCOG00106","COG1797","Cobyrinic acid a,c-diamide synthase",1.271114,1E-006,0.741461,0.003234,1.107943,0.000693]
["MA0110","L","arCOG00488","COG0592","DNA polymerase III sliding clamp (beta) subunit, PCNA homolog",2.435886,2E-006,1.226583,0.004166,1.923391,0.000152]
["MA0113","F","arCOG09021","COG1051","ADP-ribose pyrophosphatase YjhB, NUDIX family",1.805663,0,1.034818,0.001344,1.482988,0.000152]
["MA0118","E","arCOG04273","COG0079","Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase",1.704993,0,1.065102,0.001539,1.40837,0.000196]
["MA0119","E","arCOG00914","COG4992","Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase",1.325617,8E-006,0.959378,0.00164,1.128676,0.000446]
["MA0121","J","arCOG00991","COG1370","tRNA-guanine transglycosylase, archaeosine-15-forming",0.913335,0.000263,0.759358,0.009454,0.837546,0.002046]
["MA0122","-","-","-","-",1.49878,0,0.854493,3.2E-005,1.2757,0.000309]
["MA0128","S","arCOG04845","COG4081","Uncharacterized protein",1.115092,0.000158,0.906748,0.004918,0.967657,0.000764]
["MA0130","F","arCOG00639","COG0150","Phosphoribosylaminoimidazole (AIR) synthetase",2.155815,7.5E-005,1.491921,0.000582,1.683726,0.000152]
["MA0131","E","arCOG00861","COG0527","Aspartokinase",2.004206,2.7E-005,1.311129,0.001412,1.604128,0.000152]
["MA0132","G","arCOG01696","COG3635","2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archeal type",1.356007,0.000829,1.154712,0.001439,1.126857,0.000398]
["MA0141","V","arCOG04942","COG0841","Multidrug efflux pump subunit AcrB",3.843547,0,2.368784,0,2.931757,0]
["MA0143","E","-","COG0833","Amino acid permease",4.02346,0,2.90311,0,3.035821,0]
["MA0144","-","-","-","-",6.793116,0,5.522385,0,4.900822,0]
["MA0145","C","arCOG02032","COG5012","Methanogenic corrinoid protein MtbC1",7.120392,0,5.204306,0,5.1505,0]
["MA0146","H","arCOG03325","COG0407","Uroporphyrinogen-III decarboxylase",6.115066,0,4.027365,0,4.442468,0]
["MA0150","S","arCOG02036","COG3894","Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain",1.422839,0,1.06972,0,1.202633,0.000383]
["MA0152","I","arCOG00247","COG2084","3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase",2.317279,0,0.909745,0.000185,1.872769,0.000152]
["MA0154","H","arCOG00659","COG0502","Biotin synthase or related enzyme",2.772084,0,1.412265,0,2.187664,0.000123]
["MA0155","J","arCOG00409","COG0017","Aspartyl/asparaginyl-tRNA synthetase",2.503668,0,1.645337,3E-006,1.972589,0.000152]
["MA0156","-","-","-","-",1.108745,1E-006,0.979546,0.000109,0.965759,0.000822]
["MA0164","S","arCOG05002","COG3482","Uncharacterized protein",1.069541,2.4E-005,0.776459,0.007833,0.947818,0.000921]
["MA0165","J","arCOG02882","COG1944","Ribosomal protein S12 methylthiotransferase accessory factor YcaO",0.98253,0.005032,0.88611,0.008237,0.866971,0.001067]
["MA0171","J","arCOG00410","COG0016","Phenylalanyl-tRNA synthetase alpha subunit",1.982923,1E-005,1.328192,0.000683,1.58687,0.000152]
["MA0172","J","arCOG01887","COG0180","Tryptophanyl-tRNA synthetase",1.524951,5.9E-005,1.142318,0.00141,1.262162,0.000297]
["MA0182","J","arCOG01640","COG1601","Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain",3.266299,1E-006,1.872658,3.2E-005,2.464884,6.9E-005]
["MA0183","J","arCOG04113","COG0197","Ribosomal protein L16/L10AE",3.240209,0,1.770458,6.2E-005,2.46277,0]
["MA0194","J","arCOG01255","COG0013","Alanyl-tRNA synthetase",1.717305,0.00012,1.081036,0.004804,1.408616,0.000261]
["MA0201","CE","arCOG01163","COG0473","Isocitrate/isopropylmalate dehydrogenase",2.489251,1.5E-005,1.598219,0.000287,1.922828,0.000152]
["MA0202","E","arCOG02230","COG0066","3-isopropylmalate dehydratase small subunit",3.451273,0,1.774632,8.3E-005,2.617727,0]
["MA0206","F","arCOG04346","COG1759","5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase (purine biosynthesis)",1.691197,1E-006,1.026356,0.003071,1.39761,0.000196]
["MA0210","S","arCOG04424","COG3377","Uncharacterized protein YunC, DUF1805 family",0.986842,3E-006,0.870534,0.000479,0.882411,0.001686]
["MA0211","-","-","-","-",1.23073,0,1.226633,0,1.033417,0.000398]
["MA0212","J","arCOG01001","COG0024","Methionine aminopeptidase",1.198916,6E-006,0.870351,0.000452,1.044132,0.000754]
["MA0213","E","arCOG01003","COG0006","Xaa-Pro aminopeptidase",1.245915,4E-006,1.072541,2.3E-005,1.058819,0.000537]
["MA0217","E","arCOG02208","COG0040","ATP phosphoribosyltransferase",2.329774,0,1.174442,0.000369,1.86595,0.000152]
["MA0218","E","arCOG00618","COG0106","Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase",1.844543,0.00253,1.250821,0.00712,1.446855,0.000152]
["MA0219","E","arCOG04398","COG0131","Imidazoleglycerol phosphate dehydratase HisB",1.681858,3.8E-005,1.293074,0.000804,1.359801,0.000186]
["MA0241","G","arCOG00768","COG1109","Phosphomannomutase",1.543307,1E-005,0.975103,0.004251,1.289608,0.000297]
["MA0244","R","arCOG04279","COG1786","Swiveling domain associated with predicted aconitase",1.721747,0,0.72963,0.008237,1.442712,0.000261]
["MA0249","C","arCOG04237","COG0372","Citrate synthase",0.889972,0.000666,0.655388,0.008949,0.825325,0.001671]
["MA0284","S","arCOG02079","COG1361","Uncharacterized conserved protein",1.568473,0.000381,1.059702,0.008154,1.293491,0.000261]
["MA0285","S","arCOG02079","COG1361","Uncharacterized conserved protein",1.113861,0.004809,0.950124,0.008697,0.959618,0.000822]
["MA0304","C","arCOG00764","COG2191","Formylmethanofuran dehydrogenase subunit E",3.105592,0,2.462243,0,2.336613,0]
["MA0305","C","arCOG01543","COG1143","Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)",2.889147,0,2.362903,0,2.17064,6.9E-005]
["MA0306","C","arCOG04461","COG1229","Formylmethanofuran dehydrogenase subunit A",2.528178,2E-006,1.973154,2E-006,1.937018,0.000152]
["MA0307","C","arCOG00097","COG2218","Formylmethanofuran dehydrogenase subunit C",2.725689,0,2.238223,0,2.054407,6.9E-005]
["MA0308","C","arCOG02674","COG1153","Formylmethanofuran dehydrogenase subunit D",2.753531,0,1.978948,0,2.128891,0]
["MA0309","C","arCOG01498","COG1029","Formylmethanofuran dehydrogenase subunit B",2.666654,0,2.187332,0,2.0191,0.000123]
["MA0323","G","arCOG05705","COG3839","ABC-type sugar transport system, ATPase component",0.966745,0.000179,0.815099,0.003643,0.867063,0.00113]
["MA0324","P","arCOG00164","COG0555","ABC-type sulfate transport system, permease component",1.644862,0,1.02323,0.000962,1.359633,0.000186]
["MA0325","P","arCOG00219","COG0725","ABC-type molybdate transport system, periplasmic component",1.183053,5.1E-005,0.855378,0.005393,1.032258,0.000798]
["MA0334","V","arCOG01731","COG0534","Na+-driven multidrug efflux pump",1.505763,0,0.792669,0.002826,1.282792,0.000398]
["MA0339","R","arCOG01026","COG1907","Predicted archaeal sugar kinase",2.353651,0,1.07123,0.006193,1.877807,0.000152]
["MA0340","J","arCOG01923","COG1498","RNA processing factor Prp31, contains Nop domain",1.817396,0.000639,1.252544,0.004495,1.443667,0.000152]
["MA0369","S","arCOG02701","COG1641","Uncharacterized conserved protein, DUF111 family",1.750923,0,0.817968,0.007099,1.453068,0.000196]
["MA0370","-","-","-","-",3.039183,3E-006,1.39438,0.002332,2.343303,6.9E-005]
["MA0372","F","arCOG00858","COG0528","Uridylate kinase",1.563908,0,0.932938,0.001112,1.316967,0.000261]
["MA0381","C","arCOG00764","COG2191","Formylmethanofuran dehydrogenase subunit E",1.594118,0.001568,1.169318,0.007355,1.284576,0.000196]
["MA0428","F","arCOG02465","COG1691","NCAIR mutase (PurE)-related protein",1.347249,2E-006,1.156915,7.5E-005,1.129772,0.000309]
["MA0429","S","arCOG02701","COG1641","Uncharacterized conserved protein, DUF111 family",1.471002,0,1.161709,2.1E-005,1.22887,0.000297]
["MA0433","R","arCOG01234","COG0523","GTPase, G3E family",1.875684,0,1.505155,0,1.506077,0.000152]
["MA0436","R","arCOG00662","COG2516","Biotin synthase-related protein, radical SAM superfamily",1.715102,0,1.016807,0.001205,1.418895,0.000196]
["MA0439","G","arCOG04044","COG1830","Fructose-bisphosphate aldolase class Ia, DhnA family",1.905748,0.00013,1.32848,0.001681,1.515449,0.000152]
["MA0463","J","arCOG00187","COG1245","Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains",3.14195,6E-006,1.286395,0.00718,2.402176,0]
["MA0520","H","arCOG00650","COG2241","Precorrin-6B methylase 1",1.035993,0.000371,0.860619,0.008403,0.917676,0.000989]
["MA0521","H","arCOG04383","COG1903","Cobalamin biosynthesis protein CbiD",1.674714,0.000527,1.164154,0.00662,1.360905,0.000196]
["MA0523","L","arCOG02897","COG0249","DNA mismatch repair ATPase MutS",1.238409,0.002212,0.915752,0.009454,1.058346,0.000665]
["MA0527","C","arCOG02032","COG5012","Methanogenic corrinoid protein MtbC1",8.288525,0,6.823269,0,5.941661,0]
["MA0528","H","arCOG03405","COG5598","Trimethylamine:corrinoid methyltransferase",8.223557,0,5.872469,0,5.937613,0]
["MA0529","C","arCOG02032","COG5012","Methanogenic corrinoid protein MtbC1",8.13134,0,5.835657,0,5.8586,0]
["MA0531","-","-","-","-",6.950865,0,5.248405,0,5.04705,0]
["MA0532","-","-","-","-",7.33142,0,5.91576,0,5.285687,0]
["MA0542","R","arCOG01759","COG1259","Bifunctional DNase/RNase",-1.214233,0,-0.855822,0.000836,-0.672481,0.008167]
["MA0547","H","arCOG01904","COG1339","Archaeal CTP-dependent riboflavin kinase",1.431288,0.000123,1.190903,0.001236,1.178219,0.000261]
["MA0548","H","arCOG01320","COG0108","3,4-dihydroxy-2-butanone 4-phosphate synthase",1.054813,0.006088,1.048896,0.006608,0.89818,0.000968]
["MA0549","P","arCOG01480","COG0053","Divalent metal cation (Fe/Co/Zn/Cd) transporter",-1.087461,0,-0.537357,0.006546,-0.625832,0.007151]
["MA0573","R","arCOG00941","COG0535","Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family",1.335123,0.000114,0.920918,0.009261,1.133548,0.000398]
["MA0575","K","arCOG08032","COG1522","DNA-binding transcriptional regulator, Lrp family",1.145434,0,0.879386,0.000137,1.001225,0.000817]
["MA0576","H","arCOG01044","COG1648","Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)",1.015718,0,0.610171,0.005293,0.923713,0.001316]
["MA0581","H","arCOG00918","COG0001","Glutamate-1-semialdehyde aminotransferase",2.286883,0,1.243879,0.001106,1.82175,0.000152]
["MA0582","H","arCOG04299","COG0181","Porphobilinogen deaminase",2.082046,2E-006,1.324994,0.000887,1.660415,0.000152]
["MA0585","Q","arCOG00235","COG0179","2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)",1.363897,0,0.938923,0.000542,1.157756,0.000309]
["MA0586","K","arCOG01345","COG3388","Predicted transcriptional regulator",1.331815,0,0.744786,0.006096,1.143525,0.000605]
["MA0587","J","arCOG04302","COG0008","Glutamyl- or glutaminyl-tRNA synthetase",2.130829,0,1.266905,0.000272,1.710445,0.000152]
["MA0592","HR","arCOG01757","COG0111","Phosphoglycerate dehydrogenase or related dehydrogenase",2.470499,0.000128,1.408166,0.002283,1.910946,0.000152]
["MA0595","J","arCOG00780","COG1727","Ribosomal protein L18E",3.615447,2.1E-005,1.528951,0.001196,2.704126,0]
["MA0596","J","arCOG04242","COG0102","Ribosomal protein L13",3.683205,0,2.031628,2E-006,2.775791,0]
["MA0597","J","arCOG04243","COG0103","Ribosomal protein S9",3.671393,0,1.923539,1.7E-005,2.763432,0]
["MA0598","K","arCOG04244","COG1644","DNA-directed RNA polymerase, subunit N (RpoN/RPB10)",3.807376,0,1.56474,0.000852,2.880631,0]
["MA0599","K","arCOG01268","COG1758","DNA-directed RNA polymerase, subunit K/omega",3.272702,0,2.113405,0,2.469406,0]
["MA0600","J","arCOG04245","COG0052","Ribosomal protein S2",3.066664,3E-006,1.794412,6.9E-005,2.32712,6.9E-005]
["MA0601","R","arCOG01728","COG1355","Predicted class III extradiol dioxygenase, MEMO1 family",2.683259,0,1.585602,0.000137,2.085068,6.9E-005]
["MA0604","CIR","arCOG00613","COG1304","FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase",1.977243,0,0.9976,0.008977,1.607979,0.000152]
["MA0608","G","arCOG01111","COG0574","Phosphoenolpyruvate synthase/pyruvate phosphate dikinase",2.697104,0.000143,1.496521,0.001205,2.071507,0.000152]
["MA0609","J","arCOG02466","COG3277","rRNA processing protein Gar1",2.680008,0,1.13256,0.003069,2.115914,6.9E-005]
["MA0610","K","arCOG05931","COG1405","Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB",2.05532,5E-006,1.04417,0.009906,1.65931,0.000152]
["MA0617","P","arCOG01480","COG0053","Divalent metal cation (Fe/Co/Zn/Cd) transporter",0.715954,0.004361,0.687561,0.005275,0.684132,0.002201]
["MA0630","O","arCOG05153","COG0234","Co-chaperonin GroES (HSP10)",2.827041,1.5E-005,1.719916,0.000163,2.145988,6.9E-005]
["MA0631","O","arCOG05154","COG0459","Chaperonin GroEL (HSP60 family)",3.29957,3E-005,1.499073,0.00144,2.507873,6.9E-005]
["MA0639","C","arCOG01097","COG1592","Rubrerythrin",2.282727,0,1.192679,0.002462,1.819848,0.000152]
["MA0640","-","-","-","-",-1.166122,0,-0.668693,0.000119,-0.672282,0.005949]
["MA0641","R","arCOG04881","COG1379","PHP family phosphoesterase with a Zn ribbon",1.307507,0.000392,1.069065,0.002182,1.099853,0.000484]
["MA0642","R","arCOG00348","COG2047","Proteasome assembly chaperone (PAC2) family protein",1.831971,8.8E-005,1.356586,0.000852,1.463365,0.000186]
["MA0643","J","arCOG00906","COG2260","rRNA maturation protein Nop10, contains Zn-ribbon domain",3.041736,0,1.549298,0.000886,2.314424,0]
["MA0644","J","arCOG04107","COG1093","Translation initiation factor 2, alpha subunit (eIF-2alpha)",3.037131,4.7E-005,1.741221,0.000178,2.269807,6.9E-005]
["MA0645","J","arCOG04108","COG2051","Ribosomal protein S27E",3.573514,0,1.92658,2.4E-005,2.668459,0]
["MA0646","J","arCOG04109","COG1631","Ribosomal protein L44E",3.684877,0,2.07997,2E-006,2.763354,0]
["MA0647","L","arCOG00552","COG1711","DNA replication initiation complex subunit, GINS family",1.701387,0,0.804167,0.009906,1.417896,0.000196]
["MA0655","T","arCOG04453","COG1624","Diadenylate cyclase (c-di-AMP synthetase), DisA_N domain",1.584475,0,1.037028,0.000602,1.321964,0.000261]
["MA0671","J","arCOG00187","COG1245","Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains",4.062567,0,1.647584,0.000232,3.081587,0]
["MA0674","C","arCOG02095","COG5016","Pyruvate/oxaloacetate carboxyltransferase",2.01186,3.5E-005,1.265815,0.002212,1.610974,0.000152]
["MA0675","I","arCOG01591","COG4770","Acetyl/propionyl-CoA carboxylase, alpha subunit",1.934211,6.2E-005,1.343214,0.001106,1.543808,0.000186]
["MA0693","K","arCOG04853","COG4008","Predicted metal-binding transcription factor, methanogenesis marker domain 9",2.350492,3.4E-005,1.293418,0.003846,1.84667,0.000152]
["MA0694","H","arCOG04238","COG1767","Triphosphoribosyl-dephospho-CoA synthetase",2.35509,4E-006,1.313158,0.00199,1.858023,0.000123]
["MA0697","EP","arCOG07874","COG1124","ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component",-1.214703,0,-0.615038,0.006356,-0.720455,0.003527]
["MA0699","EP","arCOG00750","COG1173","ABC-type dipeptide/oligopeptide/nickel transport system, permease component",-1.10623,0,-0.531986,0.009631,-0.642317,0.009918]
["MA0708","-","-","-","-",1.319233,0.000116,0.898185,0.007981,1.128057,0.000547]
["MA0712","-","-","-","-",1.065468,2E-006,0.792917,0.002948,0.94343,0.00098]
["MA0721","K","arCOG04111","COG1761","DNA-directed RNA polymerase, subunit L",2.725982,0,1.184588,0.005026,2.137917,6.9E-005]
["MA0722","J","arCOG00091","COG1103","Archaeal Cys-tRNA synthase (O-phospho-L-seryl-tRNA:Cys-tRNA synthase)",1.433902,1.8E-005,0.940019,0.006045,1.207678,0.000297]
["MA0726","E","arCOG02268","COG0019","Diaminopimelate decarboxylase",2.160389,0,1.437638,6.8E-005,1.716263,0.000152]
["MA0750","K","arCOG07512","COG4742","Predicted transcriptional regulator, contains HTH domain",1.028889,1E-006,0.796404,0.000567,0.916039,0.001097]
["MA0752","R","arCOG05159","COG1750","Predicted archaeal serine protease, S18 family",1.275417,3E-006,0.903081,0.002643,1.093083,0.000519]
["MA0760","J","arCOG00408","COG1190","Lysyl-tRNA synthetase (class II)",1.008076,0.001402,1.130184,0.000391,0.861135,0.001037]
["MA0779","H","arCOG03325","COG0407","Uroporphyrinogen-III decarboxylase",1.124626,0,0.709063,0.000754,1.000052,0.000968]
["MA0797","GM","arCOG02877","COG0726","Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family",-1.174407,0,-0.589565,0.009074,-0.687727,0.004485]
["MA0818","R","arCOG02155","COG1873","Sporulation protein YlmC, PRC-barrel domain family",2.272993,0,0.91623,0.008001,1.828176,0.000123]
["MA0819","C","arCOG00246","COG0039","Malate/lactate dehydrogenase",1.489826,0,0.936077,0.001371,1.255732,0.000288]
["MA0825","-","-","-","-",2.568251,0,-0.658479,0.000187,2.082746,0.000261]
["MA0830","-","-","-","-",2.710556,0,0.966122,0.005954,2.147603,0.000123]
["MA0831","X","arCOG03506","COG3293","Transposase",-1.136859,0,-0.621145,0.000272,-0.656322,0.008777]
["MA0832","C","arCOG00097","COG2218","Formylmethanofuran dehydrogenase subunit C",3.451296,0,2.024323,6E-006,2.586241,0]
["MA0833","C","arCOG04461","COG1229","Formylmethanofuran dehydrogenase subunit A",3.810396,0,1.987473,4E-006,2.881889,0]
["MA0834","C","arCOG01498","COG1029","Formylmethanofuran dehydrogenase subunit B",3.595583,0,1.690952,8.3E-005,2.753073,0]
["MA0835","C","arCOG02674","COG1153","Formylmethanofuran dehydrogenase subunit D",3.463572,0,1.99766,0,2.643969,0]
["MA0858","EQ","arCOG01517","COG0145","N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit",4.035077,0,1.392153,0,3.09303,6.9E-005]
["MA0863","T","arCOG02369","COG0642","Signal transduction histidine kinase",1.598929,3.4E-005,1.179143,0.000326,1.31807,0.000261]
["MA0864","T","arCOG02367","COG2202","PAS domain",1.58645,0,1.361284,1.1E-005,1.290424,0.000196]
["MA0866","P","arCOG00320","COG0704","Phosphate uptake regulator",1.620636,9E-006,0.930701,0.009824,1.351448,0.000261]
["MA0879","EP","arCOG05410","COG0444","ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component",-1.117796,0,-0.638406,0.002212,-0.636588,0.006159]
["MA0880","EP","arCOG00750","COG1173","ABC-type dipeptide/oligopeptide/nickel transport system, permease component",-1.200924,0,-0.660508,0.00793,-0.693996,0.005192]
["MA0881","EP","arCOG00751","COG0601","ABC-type dipeptide/oligopeptide/nickel transport system, permease component",-1.020808,0,-0.64882,0.006509,-0.551607,0.007602]
["MA0889","P","arCOG00168","COG0581","ABC-type phosphate transport system, permease component",-1.116172,0,-1.112837,4E-006,-0.587428,0.009439]
["MA0890","P","arCOG00231","COG1117","ABC-type phosphate transport system, ATPase component",-1.105135,0,-0.985138,1E-006,-0.592613,0.008622]
["MA0893","L","arCOG02840","COG0415","Deoxyribodipyrimidine photolyase",1.900828,1.5E-005,1.188598,0.009423,1.508142,0.000152]
["MA0894","T","arCOG01180","COG1718","Serine/threonine-protein kinase RIO1",1.96714,0,1.219441,0.001062,1.584998,0.000152]
["MA0904","-","-","-","-",1.261146,0.000585,0.974597,0.00546,1.074437,0.000547]
["MA0917","L","arCOG00429","COG1107","Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain",1.433467,0.000146,0.923965,0.009542,1.210277,0.000398]
["MA0923","J","arCOG04154","COG2007","Ribosomal protein S8E",3.592266,0,1.894341,1.3E-005,2.72111,0]
["MA0924","K","arCOG08032","COG1522","DNA-binding transcriptional regulator, Lrp family",3.297095,1.4E-005,1.687137,0.000306,2.470267,0]
["MA0925","E","arCOG04897","COG0436","Aspartate/methionine/tyrosine aminotransferase",2.684038,0,1.661742,8.9E-005,2.078862,6.9E-005]
["MA0936","O","arCOG01716","COG0719","Fe-S cluster assembly scaffold protein SufB",1.97168,0,1.409887,6.7E-005,1.581718,0.000152]
["MA0937","O","arCOG04236","COG0396","Fe-S cluster assembly ATPase SufC",1.870651,0,1.21342,0.000545,1.523978,0.000152]
["MA0938","H","arCOG01871","COG2266","GTP:adenosylcobinamide-phosphate guanylyltransferase",1.417104,0,0.836112,0.002217,1.211533,0.000309]
["MA0939","H","arCOG04338","COG0368","Cobalamin synthase",1.098522,2.6E-005,0.910971,0.000887,0.960254,0.000822]
["MA0942","E","arCOG04273","COG0079","Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase",2.567307,0,1.870901,0,1.992315,6.9E-005]
["MA0949","J","arCOG04185","COG0184","Ribosomal protein S15P/S13E",3.646008,0,2.104172,1E-006,2.744255,0]
["MA0958","R","arCOG00254","COG1712","Predicted dinucleotide-utilizing enzyme",1.480253,0.000263,1.301844,0.000852,1.195091,0.000261]
["MA0959","H","arCOG04459","COG0379","Quinolinate synthase",1.606989,0,1.062117,0.000485,1.337678,0.000261]
["MA0969","F","arCOG00081","COG0284","Orotidine-5'-phosphate decarboxylase",1.603791,1.3E-005,1.128529,0.007939,1.304577,0.000152]
["MA0977","C","arCOG02473","COG1941","Coenzyme F420-reducing hydrogenase, gamma subunit",1.707254,0,1.250721,7.4E-005,1.396124,0.000152]
["MA1022","C","arCOG01612","COG4231","TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit",1.631919,2.7E-005,1.085254,0.002737,1.350864,0.000261]
["MA1023","C","arCOG01600","COG1014","Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit",1.565351,1E-005,1.285692,0.000295,1.280788,0.000196]
["MA1032","R","arCOG01848","COG0110","Acetyltransferase (isoleucine patch superfamily)",0.921958,2E-006,0.6057,0.005592,0.847224,0.001857]
["MA1042","-","-","-","-",1.047926,1E-005,0.445051,0.009074,0.956674,0.00113]
["MA1072","J","arCOG04070","COG0087","Ribosomal protein L3",3.186004,8.9E-005,1.629701,0.000534,2.392705,6.9E-005]
["MA1073","J","arCOG04071","COG0088","Ribosomal protein L4",2.938296,4.3E-005,1.604555,0.000578,2.234556,6.9E-005]
["MA1074","J","arCOG04072","COG0089","Ribosomal protein L23",3.039459,0,1.852936,1.2E-005,2.323031,0]
["MA1075","J","arCOG04067","COG0090","Ribosomal protein L2",3.528141,2E-006,1.751144,0.000158,2.6625,0]
["MA1076","J","arCOG04099","COG0185","Ribosomal protein S19",3.033256,0.000184,1.615868,0.000593,2.270745,6.9E-005]
["MA1077","J","arCOG04098","COG0091","Ribosomal protein L22",3.081738,2E-006,1.746229,0.000113,2.345003,6.9E-005]
["MA1078","J","arCOG04097","COG0092","Ribosomal protein S3",3.25617,4.4E-005,1.669319,0.000369,2.444372,6.9E-005]
["MA1080","J","arCOG00784","COG1588","RNase P/RNase MRP subunit p29",3.383807,0,2.053652,2E-006,2.553737,0]
["MA1081","J","arCOG04096","COG0186","Ribosomal protein S17",3.196284,2E-006,1.69776,0.000201,2.43485,0]
["MA1082","J","arCOG04095","COG0093","Ribosomal protein L14",3.262298,4.8E-005,1.643569,0.00047,2.443717,0]
["MA1083","J","arCOG04094","COG0198","Ribosomal protein L24",3.378426,9E-006,1.821948,9.1E-005,2.521138,0]
["MA1084","J","arCOG04093","COG1471","Ribosomal protein S4E",3.396557,3E-006,1.6674,0.000328,2.571175,6.9E-005]
["MA1085","J","arCOG04092","COG0094","Ribosomal protein L5",3.28207,1E-005,1.748569,0.00017,2.466239,6.9E-005]
["MA1086","J","arCOG00782","COG0199","Ribosomal protein S14",3.404002,0,1.784411,0.00012,2.553336,0]
["MA1087","J","arCOG04091","COG0096","Ribosomal protein S8",3.648829,0,1.814734,5E-006,2.782282,0]
["MA1088","J","arCOG04090","COG0097","Ribosomal protein L6P/L9E",3.634904,2E-006,1.805244,0.000106,2.721081,0]
["MA1089","J","arCOG00781","COG1717","Ribosomal protein L32E",3.266495,2.5E-005,1.59222,0.000711,2.462534,6.9E-005]
["MA1090","J","arCOG04089","COG2147","Ribosomal protein L19E",2.915954,2.2E-005,1.728839,0.000173,2.205903,6.9E-005]
["MA1091","J","arCOG04088","COG0256","Ribosomal protein L18",3.200506,5.6E-005,1.591059,0.000729,2.403122,6.9E-005]
["MA1092","J","arCOG04087","COG0098","Ribosomal protein S5",3.421799,1E-006,1.621737,0.000459,2.596674,6.9E-005]
["MA1093","J","arCOG04086","COG1841","Ribosomal protein L30/L7E",3.08743,2E-005,1.580074,0.000729,2.341295,6.9E-005]
["MA1094","J","arCOG00779","COG0200","Ribosomal protein L15",2.951227,1.3E-005,1.627482,0.000415,2.242168,6.9E-005]
["MA1104","F","arCOG01037","COG1102","Cytidylate kinase",2.005264,0,1.24243,0.00319,1.601132,0.000152]
["MA1108","J","arCOG01722","COG0099","Ribosomal protein S13",3.353818,0,2.238422,0,2.508355,6.9E-005]
["MA1109","J","arCOG04239","COG0522","Ribosomal protein S4 or related protein",3.489882,0,1.997824,9E-006,2.618831,6.9E-005]
["MA1110","J","arCOG04240","COG0100","Ribosomal protein S11",3.364118,0,1.967819,4E-006,2.553077,0]
["MA1137","O","arCOG01231","COG0378","Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase",1.416548,0,1.026514,0.000542,1.193406,0.000297]
["MA1138","R","arCOG11348","COG0375","Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)",1.079515,7.6E-005,1.02626,0.000966,0.925168,0.000822]
["MA1139","O","arCOG04428","COG0409","Hydrogenase maturation factor",1.592524,0,1.054786,3.7E-005,1.326904,0.000196]
["MA1141","C","arCOG02474","COG1740","Ni,Fe-hydrogenase I small subunit",2.716209,0,1.760854,4E-006,2.107897,6.9E-005]
["MA1142","C","arCOG01550","COG0374","Ni,Fe-hydrogenase I large subunit",2.607899,0,1.422709,0.000256,2.05572,0.000152]
["MA1143","C","arCOG05636","COG2864","Cytochrome b subunit of formate dehydrogenase",2.563326,0,1.682573,0,2.011701,6.9E-005]
["MA1163","L","arCOG00397","COG0420","DNA repair exonuclease SbcCD nuclease subunit",1.632572,2E-006,0.864272,0.004442,1.36595,0.000288]
["MA1167","FE","arCOG00067","COG0462","Phosphoribosylpyrophosphate synthetase",1.838084,0,0.907578,0.001384,1.520229,0.000186]
["MA1173","M","arCOG01373","COG1089","GDP-D-mannose dehydratase",2.212839,3E-006,1.241116,0.002233,1.759782,0.000152]
["MA1184","M","arCOG07240","COG0463","Glycosyltransferase involved in cell wall bisynthesis",1.279164,4E-006,1.137921,6.4E-005,1.076505,0.000398]
["MA1198","PH","arCOG00198","COG1120","ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component",-1.169209,0,-0.534463,0.008697,-0.693891,0.002366]
["MA1255","J","arCOG01758","COG0051","Ribosomal protein S10",3.750521,0,2.156728,1E-006,2.810177,0]
["MA1256","J","arCOG01561","COG5256","Translation elongation factor EF-1alpha (GTPase)",3.5364,8E-006,1.784634,0.000121,2.653158,6.9E-005]
["MA1257","J","arCOG01559","COG0480","Translation elongation factor EF-G, a GTPase",3.140484,6.6E-005,1.690602,0.00029,2.363881,0.000123]
["MA1258","J","arCOG04254","COG0049","Ribosomal protein S7",2.832844,3.8E-005,1.646254,0.000359,2.150214,6.9E-005]
["MA1259","J","arCOG04255","COG0048","Ribosomal protein S12",3.399546,0,1.892384,1.8E-005,2.572031,0]
["MA1260","K","arCOG01760","COG0195","Transcription antitermination factor NusA, contains S1 and KH domains",3.007586,1.5E-005,1.640865,0.000389,2.284089,6.9E-005]
["MA1261","J","arCOG01752","COG1911","Ribosomal protein L30E",2.83071,1E-006,1.755409,5.5E-005,2.169633,6.9E-005]
["MA1262","K","arCOG04257","COG0086","DNA-directed RNA polymerase, beta' subunit/160 kD subunit",2.32331,1.6E-005,1.437769,0.000885,1.818289,0.000152]
["MA1263","K","arCOG04257","COG0086","DNA-directed RNA polymerase, beta' subunit/160 kD subunit",2.618053,1.9E-005,1.412151,0.001685,2.03546,0.000152]
["MA1264","K","arCOG01762","COG0085","DNA-directed RNA polymerase, beta subunit/140 kD subunit",2.224413,8.8E-005,1.258207,0.004765,1.761897,0.000152]
["MA1265","K","arCOG01762","COG0085","DNA-directed RNA polymerase, beta subunit/140 kD subunit",2.208624,0.000267,1.354351,0.002967,1.728658,0.000152]
["MA1266","K","arCOG04258","COG2012","DNA-directed RNA polymerase, subunit H, RpoH/RPB5",3.727105,0,1.26555,0.006535,2.853194,0]
["MA1279","H","arCOG04263","COG1829","Archaeal pantoate kinase",1.199512,2.6E-005,0.826648,0.008146,1.0438,0.000676]
["MA1283","-","-","-","-",-1.08563,0,-0.538849,0.005277,-0.625649,0.010046]
["MA1298","-","-","-","-",-1.3045,0,-0.69245,0.002254,-0.780884,0.009847]
["MA1317","JU","arCOG01924","COG0252","L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D",1.40953,0.000391,0.996858,0.009023,1.179732,0.000309]
["MA1326","P","arCOG07228","COG2608","Copper chaperone CopZ",-1.224188,0,-0.722218,0.007833,-0.703604,0.00602]
["MA1332","-","-","-","-",-1.303966,0,-0.741966,3.6E-005,-0.775059,0.003275]
["MA1334","HR","arCOG01757","COG0111","Phosphoglycerate dehydrogenase or related dehydrogenase",-1.314398,0,-0.746775,0.000683,-0.774769,0.008782]
["MA1340","O","arCOG00587","COG3640","CO dehydrogenase nickel-insertion accessory protein CooC1",-1.238624,0,-0.664474,0.00684,-0.729902,0.007484]
["MA1341","C","arCOG02017","COG1853","NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family",-1.331539,0,-0.75341,0.000948,-0.7937,0.004479]
["MA1352","-","-","-","-",3.029495,0,1.693364,0.00013,2.318375,0]
["MA1374","J","arCOG00487","COG0018","Arginyl-tRNA synthetase",1.710015,0,1.188929,0.000287,1.404686,0.000152]
["MA1391","K","arCOG00610","COG2524","Predicted transcriptional regulator, contains C-terminal CBS domains",1.93686,0,1.038223,0.004332,1.584319,0.000152]
["MA1393","E","arCOG01698","COG0065","Homoaconitase/3-isopropylmalate dehydratase large subunit",2.708865,0,1.661473,2.8E-005,2.107707,6.9E-005]
["MA1395","K","arCOG09385","COG0864","Metal-responsive transcriptional regulator, contains CopG/Arc/MetJ DNA-binding domain",-0.861083,1.4E-005,-0.601772,0.008237,-0.423939,0.00848]
["MA1411","L","arCOG00554","COG1202","Superfamily II helicase, archaea-specific",1.353717,0.000159,0.910469,0.006091,1.154357,0.000497]
["MA1414","S","arCOG07765","COG2512","Uncharacterized membrane protein",2.181246,9E-006,1.166208,0.005954,1.74101,0.000152]
["MA1418","O","arCOG00185","COG1123","ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain",1.211001,0.0003,1.010151,0.002122,1.03709,0.000676]
["MA1419","H","arCOG02252","COG0619","Energy-coupling factor transporter transmembrane protein EcfT",1.448164,5E-006,1.117046,0.001112,1.216112,0.000398]
["MA1422","IQ","arCOG00857","COG0318","Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II",1.787085,7.9E-005,1.211704,0.00223,1.454717,0.000226]
["MA1423","I","arCOG01137","COG0824","Acyl-CoA thioesterase FadM",2.179735,1E-006,1.290796,0.004577,1.72225,0.000123]
["MA1446","J","arCOG04129","COG2139","Ribosomal protein L21E",3.513894,0,1.620847,0.000402,2.67081,0]
["MA1447","J","arCOG01015","COG1258","tRNA U54 and U55 pseudouridine synthase Pus10",2.659439,5.5E-005,1.613745,0.000459,2.021311,6.9E-005]
["MA1457","S","arCOG04612","COG4044","Uncharacterized protein",1.38172,0.002233,1.131863,0.006762,1.138173,0.000309]
["MA1458","R","arCOG01690","COG1719","Predicted hydrocarbon binding protein, contains 4VR domain",2.255765,0,1.172287,0.000809,1.810531,0.000123]
["MA1467","-","-","-","-",-0.872131,4E-006,-0.520177,0.006826,-0.450341,0.008422]
["MA1471","J","arCOG01988","COG2092","Translation elongation factor EF-1beta",3.164749,0,1.478843,0.001236,2.4313,0]
["MA1472","R","arCOG01989","COG2888","Predicted RNA-binding protein involved in translation, contains  Zn-ribbon domain, DUF1610 family",2.838747,0,1.562528,0.000389,2.197513,0]
["MA1475","R","arCOG01592","COG1821","Predicted ATP-dependent carboligase, ATP-grasp superfamily",1.565058,7E-006,1.187796,0.000786,1.289483,0.000196]
["MA1477","O","arCOG04772","COG0576","Molecular chaperone GrpE (heat shock protein)",4.118616,0,1.797747,8E-005,3.105325,0]
["MA1478","O","arCOG03060","COG0443","Molecular chaperone DnaK (HSP70)",3.722523,4E-006,1.674092,0.000338,2.803385,6.9E-005]
["MA1479","O","arCOG02846","COG0484","DnaJ-class molecular chaperone with C-terminal Zn finger domain",3.354376,0,1.331395,0.002461,2.588053,6.9E-005]
["MA1488","H","arCOG04472","COG1920","2-phospho-L-lactate guanylyltransferase, coenzyme F420 biosynthesis enzyme, CobY/MobA/RfbA family",2.224752,0,1.215787,7.7E-005,1.789861,0.000123]
["MA1489","H","arCOG00657","COG1060","2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)",2.189426,0,1.182231,0.000295,1.764643,0.000152]
["MA1490","H","arCOG00657","COG1060","2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)",2.752113,0,1.908195,0,2.128341,6.9E-005]
["MA1491","H","arCOG00657","COG1060","2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)",2.359918,0,1.452632,4.6E-005,1.867009,0.000123]
["MA1492","Q","arCOG01521","COG1233","Phytoene dehydrogenase-related protein",2.115029,0,1.024538,0.002912,1.715849,0.000152]
["MA1495","C","arCOG01557","COG0838","NADH:ubiquinone oxidoreductase subunit 3 (chain A)",3.986857,0,2.321509,0,3.017277,0]
["MA1496","C","arCOG01554","COG0377","NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase",4.754074,0,2.433895,0,3.552453,0]
["MA1497","C","arCOG01551","COG0852","NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)",4.970767,0,2.714192,0,3.695858,0]
["MA1498","C","arCOG01548","COG0649","NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)",4.316097,0,2.2541,0,3.224545,0]
["MA1499","C","arCOG01546","COG1005","NADH:ubiquinone oxidoreductase subunit 1 (chain H)",3.963537,0,1.365846,0.000612,3.039121,6.9E-005]
["MA1500","C","arCOG01543","COG1143","Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)",3.855101,0,2.077253,1E-006,2.914135,0]
["MA1501","C","arCOG08081","COG0839","NADH:ubiquinone oxidoreductase subunit 6 (chain J)",3.998986,0,1.238199,0.00338,3.058818,0]
["MA1503","C","arCOG08082","COG0713","NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)",4.078859,0,1.763532,9.6E-005,3.091369,0]
["MA1504","CP","arCOG01542","COG1009","NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit",4.312574,0,1.862415,1.2E-005,3.268172,0]
["MA1505","C","arCOG01538","COG1008","NADH:ubiquinone oxidoreductase subunit 4 (chain M)",3.778008,0,1.657611,0.000196,2.8908,6.9E-005]
["MA1506","C","arCOG01540","COG1007","NADH:ubiquinone oxidoreductase subunit 2 (chain N)",4.463089,0,1.770626,7.3E-005,3.37273,0]
["MA1507","-","-","-","-",4.816757,0,2.172589,2E-006,3.561345,0]
["MA1521","J","arCOG01751","COG1358","Ribosomal protein L7Ae or related RNA K-turn-binding protein",3.714967,4E-006,1.78787,0.00013,2.766322,0]
["MA1522","J","arCOG04314","COG2053","Ribosomal protein S28E/S33",3.900778,0,1.585428,0.000774,2.927045,0]
["MA1523","J","arCOG01950","COG2075","Ribosomal protein L24E",3.859963,0,1.704181,0.000236,2.911379,0]
["MA1524","F","arCOG04313","COG0105","Nucleoside diphosphate kinase",3.714385,1E-006,1.776794,0.00013,2.791442,0]
["MA1525","J","arCOG01560","COG0532","Translation initiation factor IF-2, a GTPase",3.166356,7.6E-005,1.601751,0.000663,2.383332,6.9E-005]
["MA1526","J","arCOG01946","COG2125","Ribosomal protein S6E (S10)",3.085264,2E-006,1.88392,2.7E-005,2.328435,0]
["MA1550","-","-","-","-",-1.188428,0,-0.617816,0.004918,-0.692175,0.003549]
["MA1567","H","arCOG04075","COG0214","Pyridoxal biosynthesis lyase PdxS",2.83474,8E-006,1.429962,0.001787,2.195386,6.9E-005]
["MA1584","L","arCOG04371","COG0187","DNA gyrase/topoisomerase IV, subunit B",1.186253,0.00087,0.895307,0.009269,1.023746,0.000676]
["MA1588","K","arCOG08032","COG1522","DNA-binding transcriptional regulator, Lrp family",1.224124,1E-006,0.924606,0.001003,1.049854,0.000588]
["MA1605","E","arCOG02969","COG0308","Aminopeptidase N",1.487364,2.9E-005,0.881703,0.007859,1.254277,0.000309]
["MA1610","E","arCOG01436","COG0498","Threonine synthase",1.798017,6.9E-005,1.17054,0.004117,1.458552,0.000196]
["MA1611","J","arCOG00809","COG0495","Leucyl-tRNA synthetase",1.843177,0.000166,1.194528,0.004342,1.488326,0.000196]
["MA1656","R","arCOG00626","COG1253","Hemolysin or related protein, contains CBS domains",0.990674,3E-006,0.662233,0.004442,0.89939,0.001264]
["MA1663","-","-","-","-",1.020869,1.6E-005,1.008467,0.000146,0.893114,0.001857]
["MA1664","K","arCOG05425","COG3355","Predicted transcriptional regulator",-1.436378,0,-0.773275,0.00164,-0.874896,0.00098]
["MA1671","K","arCOG04377","COG4738","Predicted transcriptional regulator",3.6458,0,1.953551,9E-006,2.764306,0]
["MA1672","G","arCOG01169","COG0148","Enolase",2.55223,0,1.267947,0.002564,2.012621,0.000152]
["MA1676","-","-","-","-",1.560622,0,1.226364,0.000164,1.287797,0.000196]
["MA1682","O","arCOG05154","COG0459","Chaperonin GroEL (HSP60 family)",3.5124,0,1.673518,0.000227,2.674537,6.9E-005]
["MA1683","G","arCOG01122","COG0120","Ribose 5-phosphate isomerase",1.493339,7E-006,1.150987,0.000788,1.240209,0.000261]
["MA1684","J","arCOG00409","COG0017","Aspartyl/asparaginyl-tRNA synthetase",2.301504,9E-006,1.535237,0.00027,1.800916,0.000152]
["MA1690","-","-","-","-",-1.626801,0,-1.398913,0,-0.959921,0.008824]
["MA1698","-","-","-","-",-1.197961,0,-0.588517,0.004789,-0.71217,0.003779]
["MA1710","H","arCOG02675","COG3252","Methenyltetrahydromethanopterin cyclohydrolase",2.845026,0,1.90405,5E-006,2.174526,6.9E-005]
["MA1712","E","arCOG04897","COG0436","Aspartate/methionine/tyrosine aminotransferase",2.050198,5E-006,1.326244,0.000886,1.635928,0.000152]
["MA1737","-","-","-","-",2.305836,0,1.184119,0.008237,1.828785,6.9E-005]
["MA1748","H","arCOG02252","COG0619","Energy-coupling factor transporter transmembrane protein EcfT",-1.13752,0,-0.676268,0.009023,-0.644031,0.003267]
["MA1765","J","-","COG5271","Midasin, AAA ATPase with  vWA domain, involved in ribosome maturation",-1.184788,0,-0.585942,0.009046,-0.693088,0.008167]
["MA1775","J","arCOG04208","COG1997","Ribosomal protein L37AE/L43A",2.83873,1E-006,1.654269,0.000138,2.178657,6.9E-005]
["MA1776","J","arCOG01574","COG2123","Exosome complex RNA-binding protein Rrp42, RNase PH superfamily",2.715582,1.6E-005,1.365807,0.002975,2.103046,6.9E-005]
["MA1777","J","arCOG00678","COG1097","Exosome complex RNA-binding protein Rrp4, contains S1 and KH domains",2.252914,0.000561,1.310312,0.005141,1.752053,0.000152]
["MA1778","J","arCOG04187","COG1500","Ribosome maturation protein Sdo1",2.249691,0.000204,1.217326,0.008262,1.768284,0.000152]
["MA1782","J","arCOG00307","COG1603","RNase P/RNase MRP subunit p30",2.084229,4E-006,1.434768,0.000385,1.648275,0.000152]
["MA1783","J","arCOG01042","COG1325","Exosome subunit, RNA binding protein with dsRBD fold",2.662101,0,1.641616,1E-006,2.081686,6.9E-005]
["MA1784","J","arCOG04209","COG1632","Ribosomal protein L15E",3.604451,0,1.918922,2.2E-005,2.707803,6.9E-005]
["MA1789","L","arCOG01527","COG0550","DNA topoisomerase IA",1.4425,4E-005,0.997112,0.002546,1.214256,0.000309]
["MA1790","H","arCOG02741","COG0422","Thiamine biosynthesis protein ThiC",1.595748,8.8E-005,1.143147,0.003603,1.314376,0.000261]
["MA1796","-","-","-","-",1.564413,0,0.907564,0.002155,1.316735,0.000261]
["MA1802","EG","arCOG04045","COG0129","Dihydroxyacid dehydratase/phosphogluconate dehydratase",2.245675,1E-006,1.119681,0.004918,1.800725,0.000152]
["MA1805","H","arCOG03221","COG4063","Tetrahydromethanopterin S-methyltransferase, subunit A",1.282453,0,0.730098,0.007968,1.110736,0.000537]
["MA1816","EF","arCOG00082","COG0075","Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG",2.470771,4E-006,1.372392,0.001503,1.938691,0.000123]
["MA1818","H","arCOG01323","COG0054","6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)",1.950292,2E-006,1.257926,0.001148,1.570984,0.000152]
["MA1819","E","arCOG04897","COG0436","Aspartate/methionine/tyrosine aminotransferase",2.245635,9.7E-005,1.214611,0.007426,1.774445,0.000152]
["MA1820","M","arCOG01222","COG0615","Glycerol-3-phosphate cytidylyltransferase, cytidylyltransferase family",1.399004,0,0.639145,0.004288,1.210477,0.000622]
["MA1822","S","arCOG02448","COG2768","Uncharacterized Fe-S center protein",1.823618,0,0.874641,0.001469,1.511667,0.000255]
["MA1827","M","arCOG01568","COG0668","Small-conductance mechanosensitive channel",1.572989,0,0.82481,0.0088,1.324434,0.000261]
["MA1850","P","arCOG04233","COG0614","ABC-type Fe3+-hydroxamate transport system, periplasmic component",-1.110747,0,-0.529262,0.008093,-0.645937,0.008568]
["MA1862","O","arCOG02161","COG0466","ATP-dependent Lon protease, bacterial type",2.851807,1E-006,1.421604,0.001371,2.217704,0.000123]
["MA1925","-","-","-","-",1.472299,0,1.052226,0.000541,1.232535,0.000261]
["MA1956","J","arCOG00412","COG0072","Phenylalanyl-tRNA synthetase beta subunit",1.772973,1.9E-005,1.194394,0.001425,1.445571,0.000196]
["MA1963","F","arCOG00102","COG0047","Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain",2.1103,0,1.164617,0.000308,1.707818,0.000152]
["MA1964","F","arCOG04462","COG1828","Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component",2.505577,0,1.525821,3E-006,1.972602,6.9E-005]
["MA1974","J","arCOG00044","COG0037","tRNA(Ile)-lysidine synthase TilS/MesJ",1.648089,0,0.721307,0.006751,1.388586,0.000261]
["MA1982","C","arCOG01612","COG4231","TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit",1.375304,5E-006,0.944536,0.000696,1.174387,0.000484]
["MA2004","J","arCOG00080","COG1189","Predicted rRNA methylase YqxC, contains S4 and FtsJ domains",0.935146,0.000202,0.860783,0.002399,0.842292,0.001423]
["MA2111","O","arCOG07513","COG0501","Zn-dependent protease with chaperone function",1.467775,0.000104,1.005224,0.008393,1.222284,0.000261]
["MA2113","-","-","-","-",1.727602,0,1.148971,0.00029,1.418156,0.000152]
["MA2114","-","-","-","-",0.757982,9.3E-005,0.60645,0.006425,0.722659,0.002912]
["MA2142","E","arCOG00112","COG0137","Argininosuccinate synthase",1.827582,0.000639,1.27024,0.004177,1.450535,0.000152]
["MA2144","EF","arCOG00064","COG0505","Carbamoylphosphate synthase small subunit",2.275192,0,1.234975,0.000738,1.818252,0.000152]
["MA2148","P","arCOG04233","COG0614","ABC-type Fe3+-hydroxamate transport system, periplasmic component",-1.131185,0,-0.599398,0.001108,-0.65592,0.008724]
["MA2149","P","arCOG01007","COG0609","ABC-type Fe3+-siderophore transport system, permease component",-1.131137,0,-0.693692,0.000211,-0.63759,0.007171]
["MA2150","PH","arCOG00198","COG1120","ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component",-1.341818,0,-0.80192,3.5E-005,-0.793396,0.002697]
["MA2170","G","arCOG07826","COG1216","Glycosyltransferase, GT2 family",-1.204129,0,-0.587095,0.009838,-0.714814,0.003438]
["MA2193","UW","-","COG5010","Flp pilus assembly protein TadD, contains TPR repeats",1.050798,0,0.849036,1.4E-005,0.936112,0.001054]
["MA2198","R","arCOG06761","COG3271","Predicted double-glycine peptidase",-1.17588,0,-0.580968,0.003676,-0.69604,0.002686]
["MA2213","-","-","-","-",-1.095063,0,-0.603786,0.002683,-0.61818,0.003156]
["MA2244","H","arCOG02622","COG1541","Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family",2.125209,0,1.299937,0.000582,1.701902,0.000152]
["MA2257","-","-","-","-",2.282255,0,1.584169,7E-006,1.808163,0.000152]
["MA2267","-","-","-","-",-1.153771,1E-006,-0.821177,0.003291,-0.634273,0.00297]
["MA2275","M","arCOG03228","COG1136","ABC-type lipoprotein export system, ATPase component",1.111699,0.001503,1.012922,0.006051,0.948521,0.000693]
["MA2334","-","-","-","-",-1.104954,1E-006,-0.58602,0.005183,-0.6327,0.003527]
["MA2361","-","-","-","-",-0.905395,0,-0.381759,0.009196,-0.498112,0.00824]
["MA2431","J","arCOG00807","COG0060","Isoleucyl-tRNA synthetase",2.08994,0.000814,1.218231,0.008529,1.650116,0.000152]
["MA2495","C","arCOG00510","COG0655","Multimeric flavodoxin WrbA",1.124468,1.3E-005,0.922447,0.00149,0.972035,0.000622]
["MA2504","-","-","-","-",-1.292248,0,-0.687126,0.000545,-0.771948,0.001748]
["MA2510","L","arCOG01527","COG0550","DNA topoisomerase IA",2.187733,1.3E-005,1.24255,0.003163,1.744735,0.000152]
["MA2514","S","arCOG04483","COG4739","Uncharacterized protein, contains ferredoxin domain",1.464414,5E-006,0.929459,0.008237,1.232332,0.000261]
["MA2533","H","arCOG01481","COG1488","Nicotinic acid phosphoribosyltransferase",1.257221,1E-006,1.064346,4E-006,1.072799,0.000547]
["MA2536","R","arCOG01849","COG0663","Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily",-2.710789,0,-2.283917,0,-1.727611,0.000822]
["MA2545","-","-","-","-",1.771092,5.5E-005,1.218114,0.001916,1.434771,0.000196]
["MA2561","T","arCOG02278","COG2203","GAF domain",3.330284,0,1.876567,0,2.56824,0]
["MA2563","-","-","-","-",1.226652,0,1.000521,0.000149,1.057743,0.000568]
["MA2583","-","-","-","-",-1.376283,0,-0.754009,0.007145,-0.837404,0.00113]
["MA2585","-","-","-","-",-1.548683,0,-0.945647,0.001392,-0.944627,0.000822]
["MA2588","-","-","-","-",-1.647834,0,-0.894038,0.002853,-1.041331,0.000547]
["MA2589","-","-","-","-",-1.501925,0,-0.860233,0.000103,-0.924451,0.004473]
["MA2590","-","-","-","-",-1.557677,0,-0.975318,0.003606,-0.935568,0.001097]
["MA2591","-","-","-","-",-1.363694,0,-0.702931,0.007576,-0.835111,0.001538]
["MA2592","-","-","-","-",-1.536645,0,-0.803871,0.004391,-0.959409,0.000822]
["MA2593","-","-","-","-",-1.545583,0,-0.854213,0.001112,-0.964832,0.000989]
["MA2594","-","-","-","-",-1.682808,0,-1.005999,0,-1.060135,0.000989]
["MA2595","-","-","-","-",-1.185858,0,-0.725869,0.005083,-0.669782,0.002452]
["MA2604","-","-","-","-",-1.678713,0,-1.028381,3E-006,-1.044648,0.001792]
["MA2605","-","-","-","-",-1.803594,0,-1.036997,0.000353,-1.141645,0.000255]
["MA2606","-","-","-","-",-1.532305,0,-0.882732,0.00033,-0.948141,0.000764]
["MA2607","-","-","-","-",-1.361344,0,-0.856422,0.001685,-0.801583,0.001316]
["MA2615","S","arCOG01907","COG2013","Uncharacterized conserved protein, AIM24 family",2.337228,0,1.348348,0.000208,1.857253,0.000123]
["MA2690","G","arCOG04435","COG1892","Phosphoenolpyruvate carboxylase",1.616967,0,0.789524,0.005088,1.368781,0.000297]
["MA2714","E","arCOG00627","COG2021","Homoserine acetyltransferase",2.428614,0.000445,1.220693,0.009338,1.903832,0.000152]
["MA2716","H","arCOG04459","COG0379","Quinolinate synthase",3.237619,0,1.354523,0.002592,2.4988,6.9E-005]
["MA2717","O","arCOG02077","COG0822","NifU homolog involved in Fe-S cluster formation",2.975209,9E-006,1.440173,0.001952,2.290198,6.9E-005]
["MA2718","E","arCOG00066","COG1104","Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme",2.859684,0.000178,1.230668,0.009824,2.209573,0.000152]
["MA2746","K","arCOG02643","COG1309","DNA-binding transcriptional regulator, AcrR family",0.572437,0.003408,0.621163,0.00401,0.581765,0.00481]
["MA2813","O","arCOG00981","COG1047","FKBP-type peptidyl-prolyl cis-trans isomerase 2",3.40517,0,1.868791,2.7E-005,2.5786,0]
["MA2828","H","arCOG04454","COG0327","Putative GTP cyclohydrolase 1 type 2, NIF3 family",0.716349,0.000293,0.594836,0.00642,0.694121,0.002675]
["MA2873","-","-","-","-",-1.439724,0,-0.790503,5E-006,-0.887485,0.000879]
["MA2896","J","arCOG00401","COG0441","Threonyl-tRNA synthetase",2.702165,3E-006,1.372924,0.002061,2.10754,0.000123]
["MA2909","C","arCOG01599","COG1013","Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit",2.70105,1E-006,1.227425,0.004641,2.121909,0.000123]
["MA2910","C","arCOG01607","COG0674","Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit",2.218917,0.000108,1.17399,0.00961,1.761917,0.000152]
["MA2912","I","arCOG01529","COG0365","Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase",2.487723,1E-006,1.590424,0.0001,1.94711,0.000152]
["MA2914","R","arCOG03444","COG1917","Cupin domain protein related to quercetin dioxygenase",2.885917,0,1.632828,0.000131,2.226903,0]
["MA2919","-","-","-","-",0.960296,3.7E-005,0.9014,0.001017,0.860151,0.001577]
["MA2934","S","arCOG02640","COG1392","Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family",3.463233,0,1.098224,0.002924,2.680983,0]
["MA2971","C","arCOG02032","COG5012","Methanogenic corrinoid protein MtbC1",1.334822,5.1E-005,1.243746,0.000308,1.106597,0.000297]
["MA2972","-","-","-","-",0.785404,0.003422,0.852373,0.002235,0.730424,0.002026]
["MA2986","EH","arCOG00086","COG0512","Anthranilate/para-aminobenzoate synthase component II",2.160099,0,1.576557,0.000108,1.704238,0.000123]
["MA2987","EH","arCOG02014","COG0147","Anthranilate/para-aminobenzoate synthases component I",2.760468,1.3E-005,2.123021,2E-006,2.050046,0.000152]
["MA2988","E","arCOG01983","COG0135","Phosphoribosylanthranilate isomerase",2.46621,0,2.046638,1E-006,1.871788,0.000123]
["MA2989","E","arCOG02012","COG0547","Anthranilate phosphoribosyltransferase",2.781849,3E-006,2.176096,0,2.075809,6.9E-005]
["MA2990","E","arCOG01086","COG0159","Tryptophan synthase alpha chain",2.005764,6E-006,1.856843,2E-006,1.545161,0.000152]
["MA2991","E","arCOG01433","COG0133","Tryptophan synthase beta chain",2.376066,2.1E-005,1.934523,6E-006,1.795263,0.000152]
["MA2992","E","arCOG01088","COG0134","Indole-3-glycerol phosphate synthase",2.238521,0,1.471671,0.000827,1.752147,6.9E-005]
["MA3013","OJ","arCOG04142","COG1899","Deoxyhypusine synthase",1.452498,0.000213,1.092822,0.002781,1.212876,0.000309]
["MA3014","K","arCOG04366","COG4860","Predicted DNA-binding transcriptional regulator, ArsR family",2.451708,0,1.139408,0.006181,1.94349,6.9E-005]
["MA3032","G","arCOG02951","COG0296","1,4-alpha-glucan branching enzyme",-1.190726,0,-0.588705,0.00401,-0.705281,0.00814]
["MA3033","H","arCOG00649","COG0007","Uroporphyrinogen-III methylase (siroheme synthase)",1.806906,1E-006,1.314895,0.000359,1.457283,0.000152]
["MA3034","H","arCOG02048","COG1587","Uroporphyrinogen-III synthase",1.727913,0,1.104202,0.000542,1.422957,0.000186]
["MA3035","R","arCOG00941","COG0535","Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family",2.241175,0,1.433005,0.000326,1.773054,0.000123]
["MA3045","J","arCOG04131","COG0030","16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)",-1.222516,0,-0.602311,0.00662,-0.727318,0.002366]
["MA3046","EP","arCOG05410","COG0444","ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component",-1.365906,0,-0.705078,0.00149,-0.828662,0.001728]
["MA3052","J","arCOG00808","COG0525","Valyl-tRNA synthetase",2.085637,4.4E-005,1.379349,0.000953,1.654537,0.000152]
["MA3099","T","arCOG01693","COG0467","RecA-superfamily ATPase, KaiC/GvpD/RAD55 family",2.011932,0,0.626287,0.007859,1.656865,0.000152]
["MA3130","K","arCOG04377","COG4738","Predicted transcriptional regulator",4.523185,0,2.77388,0,3.342552,0]
["MA3149","-","-","-","-",1.217606,3.4E-005,0.802041,0.008237,1.062063,0.000693]
["MA3174","-","-","-","-",-1.291532,0,-0.830206,2.4E-005,-0.75508,0.008398]
["MA3187","G","arCOG02996","COG0662","Mannose-6-phosphate isomerase, cupin superfamily",-1.004145,0,-0.500577,0.007181,-0.561317,0.00824]
["MA3193","F","arCOG00093","COG0034","Glutamine phosphoribosylpyrophosphate amidotransferase",2.826143,1E-006,1.388374,0.001583,2.203869,6.9E-005]
["MA3194","J","arCOG04126","COG2126","Ribosomal protein L37E",4.686285,0,1.251774,0.008253,3.531986,0]
["MA3195","K","arCOG00998","COG1958","Small nuclear ribonucleoprotein (snRNP) homolog",2.387887,0.000165,1.590597,0.000487,1.818203,6.9E-005]
["MA3198","E","arCOG01432","COG1350","Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB)",1.368844,0.002975,1.091197,0.008689,1.137759,0.000497]
["MA3227","-","-","-","-",-1.196184,0,-0.528098,0.008154,-0.721568,0.004235]
["MA3250","H","arCOG00107","COG1492","Cobyric acid synthase",1.570741,1E-006,1.278828,1.5E-005,1.296333,0.000261]
["MA3263","R","arCOG03636","COG1380","Putative effector of murein hydrolase LrgA, UPF0299 family",1.028554,0,0.734432,0.0001,0.927677,0.001477]
["MA3277","-","-","-","-",-1.390803,0,-0.695826,0.001053,-0.855391,0.00113]
["MA3279","F","arCOG00063","COG0504","CTP synthase (UTP-ammonia lyase)",1.633012,0.001873,1.244303,0.004608,1.30526,0.000261]
["MA3280","-","-","-","-",1.061459,0.001258,0.910248,0.008237,0.929238,0.000921]
["MA3287","R","arCOG00321","COG0312","Predicted Zn-dependent protease or its inactivated homolog",2.284368,0,1.320014,0.000793,1.814899,0.000152]
["MA3288","R","arCOG00321","COG0312","Predicted Zn-dependent protease or its inactivated homolog",2.285747,0.000141,1.463421,0.001231,1.773156,0.000152]
["MA3289","O","arCOG02160","COG1067","Predicted ATP-dependent protease",3.011657,3E-006,1.379391,0.002539,2.327007,0.000123]
["MA3300","H","arCOG00535","COG2104","Sulfur carrier protein ThiS (thiamine biosynthesis)",4.215237,0,1.372672,0.003846,3.187267,0]
["MA3309","F","arCOG04415","COG0151","Phosphoribosylamine-glycine ligase",1.967342,0,1.249386,0.00047,1.584761,0.000152]
["MA3322","C","arCOG02017","COG1853","NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family",-1.06267,5E-006,-0.831961,0.003121,-0.548939,0.005931]
["MA3342","E","arCOG02093","COG0119","Isopropylmalate/homocitrate/citramalate synthases",2.759991,0,1.563543,0.000136,2.155169,6.9E-005]
["MA3372","O","arCOG02734","COG1433","Predicted Fe-Mo cluster-binding protein, NifX family",1.261468,0,0.684008,0.001053,1.102025,0.000676]
["MA3382","E","arCOG01909","COG0174","Glutamine synthetase",3.212574,2.5E-005,1.789749,0.000113,2.403599,6.9E-005]
["MA3387","-","-","-","-",1.480191,1.6E-005,1.017531,0.001108,1.24614,0.000297]
["MA3416","J","arCOG04186","COG1890","Ribosomal protein S3AE",2.872076,1E-006,1.552907,0.000485,2.222394,6.9E-005]
["MA3418","-","-","-","-",0.988413,0.001093,0.705449,0.007781,0.895508,0.00113]
["MA3432","L","arCOG05692","COG0608","Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation",1.670101,0,0.967987,0.003785,1.386675,0.000196]
["MA3468","K","arCOG05450","COG1321","Mn-dependent transcriptional regulator, DtxR family",1.021399,0.000163,0.934273,0.002217,0.887987,0.000822]
["MA3485","U","arCOG05911","COG1826","Sec-independent protein translocase protein TatA",2.29475,0,1.495436,0.000814,1.780045,6.9E-005]
["MA3486","U","arCOG05911","COG1826","Sec-independent protein translocase protein TatA",1.699238,0,1.224821,0.000115,1.388857,0.000152]
["MA3502","X","arCOG03474","COG5421","Transposase",-1.324683,0.000135,-1.228839,0.004575,-0.691846,0.004157]
["MA3519","H","arCOG04538","COG0190","5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase",2.28841,0,1.592655,3.3E-005,1.79676,0.000123]
["MA3520","E","arCOG00070","COG0112","Glycine/serine hydroxymethyltransferase",2.414957,0,1.39889,0.000376,1.90709,0.000123]
["MA3522","F","arCOG02825","COG0299","Folate-dependent phosphoribosylglycinamide formyltransferase PurN",1.687393,0,1.386031,0,1.377768,0.000152]
["MA3525","J","arCOG01115","COG1571","tRNA(Ile2) C34 agmatinyltransferase TiaS",1.341762,1.6E-005,0.978346,0.002462,1.140245,0.000446]
["MA3526","H","arCOG00069","COG0171","NH3-dependent NAD+ synthetase",0.969565,9.3E-005,0.73763,0.008952,0.879104,0.001309]
["MA3527","MDT","arCOG04368","COG0464","AAA+-type ATPase, SpoVK/Ycf46/Vps4 family",1.827585,0.000981,1.16879,0.008977,1.464304,0.000196]
["MA3547","-","-","-","-",1.411164,0,0.822359,0.005513,1.20362,0.000497]
["MA3553","P","arCOG04384","COG1930","ABC-type cobalt transport system, periplasmic component",1.143557,0,0.958585,0.000112,0.988121,0.000921]
["MA3558","-","-","-","-",-1.376523,0,-1.020337,0.000511,-0.782372,0.001264]
["MA3559","J","arCOG04249","COG1746","tRNA nucleotidyltransferase (CCA-adding enzyme)",1.1961,0,0.636286,0.001013,1.062346,0.000921]
["MA3566","E","arCOG00495","COG0002","N-acetyl-gamma-glutamylphosphate reductase",1.564352,0,0.936927,0.003315,1.313192,0.000261]
["MA3576","-","-","-","-",0.996129,6E-006,0.692165,0.004057,0.896319,0.001037]
["MA3589","O","arCOG01841","COG0071","Molecular chaperone IbpA, HSP20 family",2.767566,0,1.506088,2.4E-005,2.174839,6.9E-005]
["MA3595","F","arCOG00960","COG1146","NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit",1.47236,0,0.583143,0.005095,1.261594,0.000989]
["MA3618","-","-","-","-",-1.237833,0,-0.597757,0.00945,-0.742312,0.002116]
["MA3626","H","arCOG00106","COG1797","Cobyrinic acid a,c-diamide synthase",1.912655,0,0.922452,0.009338,1.565656,0.000152]
["MA3627","P","arCOG00590","COG1348","Nitrogenase subunit NifH, an ATPase",1.412234,0.000216,1.125556,0.002981,1.170419,0.000297]
["MA3630","M","arCOG02822","COG0770","UDP-N-acetylmuramyl pentapeptide synthase",1.78623,3E-006,1.156042,0.000802,1.464889,0.000196]
["MA3631","H","arCOG05434","COG2138","Sirohydrochlorin ferrochelatase",3.492036,0,2.062951,0,2.656054,0]
["MA3664","S","arCOG03509","COG3291","PKD repeat",1.434542,0.000123,1.097102,0.001096,1.198272,0.000309]
["MA3676","P","arCOG05270","COG1119","ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA",0.972092,0.000347,0.825401,0.007338,0.874316,0.001316]
["MA3684","S","arCOG04411","COG4749","Uncharacterized protein",1.941571,0.00011,1.146928,0.008025,1.561133,0.000152]
["MA3685","FL","arCOG04477","COG1860","Uncharacterized conserved protein, UPF0179 family",1.659524,0.000557,1.2818,0.00238,1.325416,0.000152]
["MA3689","F","arCOG04346","COG1759","5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase (purine biosynthesis)",1.916891,1.7E-005,1.133886,0.004902,1.554284,0.000152]
["MA3690","J","arCOG01563","COG5257","Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)",2.228904,1.2E-005,1.298306,0.002175,1.766615,0.000152]
["MA3691","J","arCOG04312","COG1412","rRNA-processing protein FCF1",2.631043,0,1.348992,0.002182,2.053984,6.9E-005]
["MA3692","K","arCOG00675","COG1095","DNA-directed RNA polymerase, subunit E'/Rpb7",2.456793,2.3E-005,1.378403,0.00216,1.91258,6.9E-005]
["MA3693","K","arCOG04077","COG2093","RNA polymerase subunit RPABC4/transcription elongation factor Spt4",2.30501,4.4E-005,1.262669,0.007837,1.787877,6.9E-005]
["MA3694","S","arCOG04076","COG1909","Uncharacterized protein, UPF0218 family",3.410651,5E-006,1.739219,0.000185,2.551724,0]
["MA3695","J","arCOG04182","COG2004","Ribosomal protein S24E",3.49791,2E-006,1.824229,8.3E-005,2.614415,0]
["MA3696","J","arCOG04183","COG1998","Ribosomal protein S27AE",3.598516,0,1.602051,2E-006,2.766005,0]
["MA3706","F","arCOG04184","COG0127","Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family",2.154279,5E-006,1.34713,0.003069,1.684076,6.9E-005]
["MA3708","-","-","-","-",-1.273516,0,-0.713371,0.003738,-0.749078,0.002068]
["MA3711","S","arCOG00932","COG2108","Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme",0.762912,0.001996,0.728159,0.008542,0.711455,0.002026]
["MA3729","G","arCOG01111","COG0574","Phosphoenolpyruvate synthase/pyruvate phosphate dikinase",-1.364872,0,-0.739167,0.000232,-0.8265,0.00113]
["MA3731","H","arCOG00972","COG1056","Nicotinamide mononucleotide adenylyltransferase",3.818161,0,1.790005,0.000125,2.864463,0]
["MA3732","C","arCOG02653","COG1035","Coenzyme F420-reducing hydrogenase, beta subunit",4.090534,1E-005,1.86269,6.6E-005,3.00859,6.9E-005]
["MA3733","HR","arCOG02410","COG2141","Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)",5.283302,0,2.646835,0,3.881478,0]
["MA3738","-","-","-","-",3.803517,0,-0.704641,0.004483,2.947975,6.9E-005]
["MA3786","HC","arCOG02199","COG0543","NAD(P)H-flavin reductase",1.390352,0.00022,0.938358,0.009286,1.179859,0.000422]
["MA3787","ER","arCOG01292","COG0493","NADPH-dependent glutamate synthase beta chain or related oxidoreductase",2.07513,0.000289,1.384946,0.002103,1.622585,0.000152]
["MA3788","-","-","-","-",-1.31439,0,-0.792446,0.001597,-0.767178,0.005437]
["MA3789","C","arCOG00288","COG0778","Nitroreductase",0.806103,0.001564,0.7687,0.009046,0.741727,0.001857]
["MA3790","EH","arCOG04465","COG0059","Ketol-acid reductoisomerase",2.907375,1E-006,1.81619,3.4E-005,2.211803,6.9E-005]
["MA3791","E","arCOG00811","COG0440","Acetolactate synthase, small subunit",3.203337,0,2.137024,1E-006,2.406109,6.9E-005]
["MA3792","EH","arCOG01614","COG0028","Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme",3.09069,0,1.591047,0.000232,2.386647,6.9E-005]
["MA3793","E","arCOG02093","COG0119","Isopropylmalate/homocitrate/citramalate synthases",3.395519,0,1.936724,5E-006,2.582053,6.9E-005]
["MA3849","EG","arCOG01519","COG1363","Putative aminopeptidase FrvX",1.593923,0,0.926897,0.001952,1.336897,0.000261]
["MA3850","O","arCOG01342","COG1382","Prefoldin, chaperonin cofactor",2.323717,8.7E-005,1.379586,0.002338,1.802613,6.9E-005]
["MA3851","F","arCOG01565","COG0618","nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs",1.773679,1.1E-005,1.088393,0.004742,1.45293,0.000196]
["MA3856","S","arCOG04885","COG4020","Uncharacterized protein",1.079043,0,0.704003,0.001093,0.965668,0.000989]
["MA3857","S","arCOG02408","COG1432","Uncharacterized conserved protein, LabA/DUF88 family",1.532786,4E-006,1.031916,0.002654,1.272077,0.000196]
["MA3870","R","arCOG01595","COG2232","Predicted ATP-dependent carboligase, ATP-grasp superfamily",1.365634,5.1E-005,1.067921,0.001106,1.149279,0.000309]
["MA3873","O","arCOG00970","COG0638","20S proteasome, alpha and beta subunits",2.738056,4E-006,1.204199,0.007781,2.137737,6.9E-005]
["MA3876","D","arCOG14071","COG0206","Cell division GTPase FtsZ",1.966653,0.000203,1.189391,0.006734,1.572541,0.000152]
["MA3879","C","arCOG04949","COG3808","Na+ or H+-translocating membrane pyrophosphatase",3.457467,0,1.322837,0.002251,2.668396,6.9E-005]
["MA3884","D","arCOG02263","COG2450","Predicted archaeal cell division protein, SepF homolog, DUF552 family",1.888283,1E-005,1.213169,0.002139,1.52208,0.000152]
["MA3885","R","arCOG04265","COG1779","C4-type Zn-finger protein",2.203023,0,1.248189,0.000359,1.762813,0.000152]
["MA3886","J","arCOG00402","COG0442","Prolyl-tRNA synthetase",1.54082,8E-006,1.102107,0.000663,1.282346,0.000297]
["MA3887","H","arCOG04272","COG2038","NaMN:DMB phosphoribosyltransferase",1.975669,0,1.094223,0.000567,1.613355,0.000152]
["MA3907","EP","arCOG00750","COG1173","ABC-type dipeptide/oligopeptide/nickel transport system, permease component",-1.150443,0,-0.52464,0.004251,-0.677512,0.007013]
["MA3908","EP","arCOG05410","COG0444","ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component",-1.317555,0,-0.647505,0.002346,-0.799034,0.006142]
["MA3915","H","arCOG01779","COG2226","Ubiquinone/menaquinone biosynthesis C-methylase UbiE",0.892772,3.7E-005,0.653357,0.008289,0.822038,0.001716]
["MA3967","O","arCOG00185","COG1123","ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain",1.524408,0.000148,1.097705,0.002176,1.267664,0.000309]
["MA3969","I","arCOG01085","COG1646","Heptaprenylglyceryl phosphate synthase",2.968433,0,1.575946,0.000226,2.29765,6.9E-005]
["MA3970","J","arCOG04049","COG1552","Ribosomal protein L40E",3.160623,7E-006,1.569786,0.000864,2.369433,0]
["MA3978","R","arCOG04916","COG3393","Predicted acetyltransferase, GNAT family",1.612196,0.001576,1.183384,0.006918,1.293596,0.000196]
["MA3993","S","arCOG04904","COG4051","Uncharacterized protein",1.60695,1.9E-005,0.993738,0.00793,1.334771,0.000255]
["MA3995","S","arCOG04903","COG4050","Uncharacterized protein",2.11843,0,0.697276,0.006509,1.732503,0.000152]
["MA3996","S","arCOG04901","COG4029","Uncharacterized protein",1.822614,0,0.848913,0.007099,1.512386,0.000196]
["MA4004","L","arCOG04050","COG0258","5'-3' exonuclease",0.715247,0.000481,0.597067,0.005507,0.692048,0.002504]
["MA4012","F","arCOG02824","COG0138","AICAR transformylase/IMP cyclohydrolase PurH",2.404193,4E-006,1.203535,0.005087,1.903827,0.000152]
["MA4020","PR","arCOG00188","COG1122","Energy-coupling factor transporter ATP-binding protein EcfA2",1.04698,3E-005,0.933706,0.00044,0.918685,0.00092]
["MA4040","K","arCOG04060","COG1709","Predicted transcriptional regulator",2.142437,0,0.97382,0.001891,1.744642,0.000152]
["MA4041","I","arCOG01767","COG3425","3-hydroxy-3-methylglutaryl CoA synthase",2.999208,0,1.812882,5E-006,2.313891,6.9E-005]
["MA4042","I","arCOG01278","COG0183","Acetyl-CoA acetyltransferase",2.895814,0,1.774529,1.4E-005,2.234199,6.9E-005]
["MA4043","R","arCOG01289","COG1545","Uncharacterized OB-fold protein, contains Zn-ribbon domain",2.786997,0,1.972669,0,2.142464,0]
["MA4044","TR","arCOG01723","COG1437","Adenylate cyclase class IV, CYTH domain (includes archaeal enzymes of unknown function)",2.326269,0,1.726885,1E-006,1.817511,6.9E-005]
["MA4048","J","arCOG00403","COG0172","Seryl-tRNA synthetase",2.153102,4E-006,1.452159,0.000232,1.704815,0.000152]
["MA4049","-","-","-","-",2.33761,0,1.346888,0.000268,1.854146,0.000152]
["MA4055","F","arCOG00641","COG0046","Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain",2.08488,6E-006,1.341273,0.000612,1.665628,0.000152]
["MA4060","R","arCOG00023","COG2522","Predicted transcriptional regulator",2.822454,0,1.241972,0.007181,2.197495,0]
["MA4063","F","arCOG04421","COG0152","Phosphoribosylaminoimidazole-succinocarboxamide synthase",2.528453,0,1.417872,0.000146,1.990983,6.9E-005]
["MA4095","FR","arCOG00700","COG0402","Cytosine/adenosine deaminase or related metal-dependent hydrolase",1.613105,0.0003,1.019916,0.008983,1.33536,0.000297]
["MA4096","-","-","-","-",3.542754,5E-006,1.504171,0.001392,2.679933,6.9E-005]
["MA4102","E","arCOG00455","COG0345","Pyrroline-5-carboxylate reductase",1.448084,4E-006,0.954203,0.004332,1.217891,0.000261]
["MA4110","O","arCOG01341","COG1730","Prefoldin subunit 5",2.614224,1.1E-005,1.676089,0.000161,2.003116,6.9E-005]
["MA4111","J","arCOG04175","COG2157","Ribosomal protein L20A (L18A)",3.091377,1E-006,1.425906,0.002643,2.35653,0]
["MA4112","J","arCOG04176","COG1976","Translation initiation factor 6 (eIF-6)",3.481089,0,1.625716,0.000312,2.654835,0]
["MA4113","J","arCOG04473","COG2097","Ribosomal protein L31E",2.795586,1.1E-005,1.629291,0.000328,2.140791,6.9E-005]
["MA4114","J","arCOG04177","COG2167","Ribosomal protein L39E",3.108743,2E-006,1.347211,0.004665,2.380827,0]
["MA4115","J","arCOG00037","COG2117","Predicted subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain",3.126504,1E-006,1.716605,0.000142,2.38791,6.9E-005]
["MA4116","R","arCOG05529","COG2118","DNA-binding TFAR19-related protein, PDSD5 family",2.939126,0.000284,1.487218,0.001678,2.204289,6.9E-005]
["MA4117","J","arCOG01344","COG2238","Ribosomal protein S19E (S16A)",4.060219,0,1.893072,3.1E-005,3.047475,0]
["MA4118","F","arCOG04387","COG0104","Adenylosuccinate synthase",2.047602,3E-006,1.280804,0.000707,1.647964,0.000152]
["MA4144","O","arCOG04448","COG1397","ADP-ribosylglycohydrolase",0.762304,0.000256,0.616672,0.007859,0.730359,0.002366]
["MA4145","R","arCOG00463","COG1833","Uri superfamily endonuclease",0.780948,0.001626,0.782196,0.006608,0.720741,0.004032]
["MA4150","H","arCOG01726","COG0142","Geranylgeranyl pyrophosphate synthase",1.741026,9E-006,1.116627,0.003315,1.420684,0.000152]
["MA4151","R","arCOG00941","COG0535","Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family",1.654199,0,0.761562,0.005088,1.394051,0.000261]
["MA4175","C","arCOG04461","COG1229","Formylmethanofuran dehydrogenase subunit A",0.795513,0.009915,1.047197,0.000232,0.714506,0.002174]
["MA4176","C","arCOG00097","COG2218","Formylmethanofuran dehydrogenase subunit C",1.948888,3E-006,1.828276,2E-006,1.51359,0.000152]
["MA4177","C","arCOG02674","COG1153","Formylmethanofuran dehydrogenase subunit D",0.924322,5.2E-005,0.755642,0.005926,0.854398,0.002037]
["MA4190","S","arCOG04412","COG4004","Uncharacterized protein",1.35418,7E-006,0.869558,0.008289,1.157294,0.000358]
["MA4194","R","arCOG04073","COG1149","MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain",6.699009,0,3.420725,0,4.915195,0]
["MA4195","R","arCOG00941","COG0535","Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family",1.707764,0.000753,1.147027,0.008262,1.379792,0.000196]
["MA4196","H","arCOG02172","COG0720","6-pyruvoyl-tetrahydropterin synthase",0.960446,6.5E-005,1.166229,3.2E-005,0.824885,0.001716]
["MA4198","S","arCOG04875","COG2029","Uncharacterized protein",0.980963,0.00082,0.962776,0.003754,0.865119,0.001623]
["MA4214","T","arCOG04434","COG3476","Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)",-1.119542,0,-0.619569,0.004671,-0.635492,0.005474]
["MA4216","E","arCOG01909","COG0174","Glutamine synthetase",1.705595,0.000153,1.09954,0.006395,1.39174,0.000196]
["MA4217","E","arCOG00095","COG0067","Glutamate synthase domain 1",2.810943,2E-006,1.839298,2.7E-005,2.141567,6.9E-005]
["MA4218","E","arCOG04553","COG0069","Glutamate synthase domain 2",2.922183,4E-006,1.569674,0.000542,2.249419,6.9E-005]
["MA4219","E","arCOG00096","COG0070","Glutamate synthase domain 3",2.582572,1.3E-005,1.371446,0.002339,2.024696,6.9E-005]
["MA4220","C","arCOG02653","COG1035","Coenzyme F420-reducing hydrogenase, beta subunit",3.108122,8E-006,1.646787,0.000369,2.363022,6.9E-005]
["MA4240","S","arCOG02290","COG2043","Uncharacterized conserved protein, DUF169 family",2.277915,0.000107,1.193763,0.008924,1.794666,0.000123]
["MA4241","R","arCOG04073","COG1149","MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain",3.562629,0,1.301281,0.001583,2.743206,6.9E-005]
["MA4242","R","arCOG04073","COG1149","MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain",3.199101,2E-006,1.473725,0.001425,2.449295,6.9E-005]
["MA4243","O","arCOG02734","COG1433","Predicted Fe-Mo cluster-binding protein, NifX family",3.174552,0,1.49771,0.000295,2.46051,6.9E-005]
["MA4244","O","arCOG02734","COG1433","Predicted Fe-Mo cluster-binding protein, NifX family",3.621838,0,1.643166,0.000287,2.761917,0]
["MA4245","R","arCOG02239","COG1342","Predicted DNA-binding protein, UPF0251 family",2.902446,0,1.896171,0,2.236351,6.9E-005]
["MA4246","D","arCOG00585","COG0489","Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster",3.126292,0,1.59245,0.00021,2.406363,6.9E-005]
["MA4251","EP","arCOG00750","COG1173","ABC-type dipeptide/oligopeptide/nickel transport system, permease component",-1.053415,0,-0.658299,0.004332,-0.572066,0.007604]
["MA4255","CO","arCOG04522","COG0785","Cytochrome c biogenesis protein CcdA",1.796693,0,0.873237,0.008977,1.491154,0.000196]
["MA4258","H","arCOG02247","COG2082","Precorrin isomerase",2.332569,0,1.552801,1.3E-005,1.844259,0.000123]
["MA4259","H","arCOG00647","COG1010","Precorrin-3B methylase",2.543426,0,1.746975,7E-006,1.97544,6.9E-005]
["MA4261","H","arCOG00645","COG2875","Precorrin-4 methylase",2.838414,0,1.868294,1E-006,2.190421,6.9E-005]
["MA4262","H","arCOG00648","COG2243","Precorrin-2 methylase",2.704488,0,1.941134,0,2.084341,6.9E-005]
["MA4265","CE","arCOG01163","COG0473","Isocitrate/isopropylmalate dehydrogenase",2.60862,5E-006,1.717915,8.3E-005,1.997687,0.000123]
["MA4266","R","arCOG00893","COG1831","Predicted metal-dependent hydrolase, urease superfamily",1.610589,0,0.975076,0.001931,1.341237,0.000196]
["MA4267","J","arCOG01863","COG1813","Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains",1.884247,0.000237,1.418381,0.000948,1.478151,0.000152]
["MA4272","U","arCOG02204","COG2443","Preprotein translocase subunit Sss1",3.880252,0,1.704294,1E-006,2.960102,0]
["MA4273","K","arCOG01920","COG0250","Transcription antitermination factor NusG",3.305669,0,1.548399,0.000211,2.542585,0]
["MA4274","J","arCOG04372","COG0080","Ribosomal protein L11",3.382634,0,1.600414,0.000323,2.581503,6.9E-005]
["MA4275","J","arCOG04289","COG0081","Ribosomal protein L1",3.837645,0,1.788473,0.000113,2.878856,0]
["MA4276","J","arCOG04288","COG0244","Ribosomal protein L10",3.574395,3E-006,1.928758,2.6E-005,2.670006,6.9E-005]
["MA4277","J","arCOG04287","COG2058","Ribosomal protein L12E/L44/L45/RPP1/RPP2",2.892932,0.000225,1.592723,0.000714,2.156943,0.000123]
["MA4281","-","-","-","-",0.845983,0.005818,0.988865,0.004332,0.740301,0.001778]
["MA4329","H","arCOG02741","COG0422","Thiamine biosynthesis protein ThiC",3.871172,0,2.266605,0,2.89147,6.9E-005]
["MA4330","M","arCOG07240","COG0463","Glycosyltransferase involved in cell wall bisynthesis",1.347322,0.000171,1.038642,0.003238,1.129068,0.000309]
["MA4339","E","arCOG04546","COG1246","N-acetylglutamate synthase or related acetyltransferase, GNAT family",2.494858,0,1.265222,0.00441,1.963839,6.9E-005]
["MA4346","KT","arCOG03455","COG1983","Phage shock protein PspC (stress-responsive transcriptional regulator)",1.279096,3E-006,1.084452,0.000308,1.081056,0.000398]
["MA4349","EH","arCOG02297","COG0115","Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase",1.783315,3E-006,1.071545,0.003279,1.460323,0.000196]
["MA4350","H","arCOG00217","COG0303","Molybdopterin biosynthesis enzyme",1.590081,2E-006,0.875118,0.006649,1.336226,0.000297]
["MA4351","J","arCOG00358","COG1163","Ribosome-interacting GTPase 1",1.776035,1E-006,1.170161,0.000651,1.454176,0.000196]
["MA4376","T","arCOG02386","COG2204","DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains",1.616627,2E-006,1.322505,0.000185,1.307064,0.000152]
["MA4379","H","arCOG03325","COG0407","Uroporphyrinogen-III decarboxylase",5.564454,0,2.440996,0,4.075366,0]
["MA4380","S","arCOG02036","COG3894","Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain",1.862034,1.2E-005,1.384738,0.000164,1.494197,0.000152]
["MA4382","R","arCOG01234","COG0523","GTPase, G3E family",1.404023,9E-006,0.843664,0.003467,1.196229,0.000484]
["MA4401","J","arCOG00357","COG0012","Ribosome-binding ATPase YchF, GTP1/OBG family",1.272258,1E-006,0.946174,0.000149,1.093781,0.000547]
["MA4403","L","arCOG00439","COG1241","DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family",1.696791,0,1.160707,0.000891,1.388188,0.000152]
["MA4404","K","arCOG02710","COG1693","Repressor of nif and glnA expression",1.550988,3.3E-005,0.997787,0.004916,1.295518,0.000297]
["MA4406","O","arCOG04236","COG0396","Fe-S cluster assembly ATPase SufC",1.421014,0.000238,1.041842,0.005153,1.184734,0.000297]
["MA4413","O","arCOG05154","COG0459","Chaperonin GroEL (HSP60 family)",3.975087,0,2.163681,1E-006,2.962452,6.9E-005]
["MA4414","S","arCOG04420","COG1935","Uncharacterized protein",1.975651,0,0.934582,0.000926,1.618091,0.000152]
["MA4415","R","arCOG00347","COG1938","Predicted ATP-dependent carboligase, ATP-grasp superfamily",2.134706,0,0.952567,0.008119,1.733129,0.000152]
["MA4419","J","arCOG00989","COG0343","Queuine/archaeosine tRNA-ribosyltransferase",1.260574,0.000365,1.017336,0.001588,1.075779,0.000588]
["MA4428","S","arCOG01162","COG1340","Uncharacterized coiled-coil protein, contains DUF342 domain",2.399357,0.000716,1.457867,0.001858,1.835732,0.000152]
["MA4429","E","arCOG05228","COG0560","Phosphoserine phosphatase",2.811445,0,1.367179,0.001164,2.192462,6.9E-005]
["MA4430","C","arCOG04382","COG1927","F420-dependent methylenetetrahydromethanopterin dehydrogenase",5.721541,0,2.781989,0,4.218332,0]
["MA4436","S","arCOG04482","COG1891","Uncharacterized protein, UPF0264 family",2.637755,0,1.451212,0.000129,2.074845,6.9E-005]
["MA4442","-","-","-","-",0.96018,0.003753,0.846729,0.00491,0.864011,0.001158]
["MA4457","M","arCOG00253","COG1004","UDP-glucose 6-dehydrogenase",1.33489,7.6E-005,0.919446,0.004206,1.136025,0.000484]
["MA4459","M","arCOG00665","COG1210","UTP-glucose-1-phosphate uridylyltransferase",1.776337,0,1.213017,0.000234,1.456647,0.000196]
["MA4473","EM","arCOG04172","COG0329","Dihydrodipicolinate synthase/N-acetylneuraminate lyase",2.746585,1.3E-005,1.50728,0.000909,2.115378,6.9E-005]
["MA4474","E","arCOG04393","COG0289","Dihydrodipicolinate reductase",2.464198,7.6E-005,1.486535,0.001117,1.899605,0.000123]
["MA4508","-","-","-","-",0.968913,7.4E-005,0.836627,0.002399,0.85883,0.001826]
["MA4513","R","arCOG01360","COG1244","Uncharacterized Fe-S cluster-containing protein. MiaB family",1.467467,1E-006,0.817646,0.008074,1.250056,0.000398]
["MA4517","H","arCOG04301","COG1469","GTP cyclohydrolase FolE2",2.409202,3E-006,1.539745,0.00021,1.886317,0.000152]
["MA4519","S","arCOG04866","COG4065","Uncharacterized protein",1.155797,0.002469,1.014406,0.003338,0.986431,0.000754]
["MA4524","J","arCOG01718","COG0064","Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit",1.54178,0.000597,1.118682,0.005374,1.267295,0.000297]
["MA4574","O","arCOG01841","COG0071","Molecular chaperone IbpA, HSP20 family",2.143326,4E-006,1.115121,0.006169,1.717942,0.000152]
["MA4576","K","arCOG01684","COG1777","Predicted transcriptional regulator",2.226331,0,1.114995,0.001853,1.78933,0.000152]
["MA4587","U","arCOG01228","COG0541","Signal recognition particle GTPase",1.526613,9.1E-005,0.997802,0.00524,1.280049,0.000309]
["MA4590","F","arCOG00087","COG0518","GMP synthase - Glutamine amidotransferase domain",1.747789,0,1.335431,3.1E-005,1.424167,0.000152]
["MA4591","G","arCOG04044","COG1830","Fructose-bisphosphate aldolase class Ia, DhnA family",2.114735,1.5E-005,1.676289,3.4E-005,1.64604,0.000152]
["MA4592","E","arCOG04353","COG1465","3-dehydroquinate synthase, class II",2.116136,4.2E-005,1.494573,0.00047,1.664462,0.000152]
["MA4593","E","arCOG02097","COG0710","3-dehydroquinate dehydratase",2.46925,0,1.541054,2.7E-005,1.940306,6.9E-005]
["MA4594","E","arCOG01033","COG0169","Shikimate 5-dehydrogenase",1.766678,3.1E-005,1.187946,0.006429,1.432921,0.000196]
["MA4595","E","arCOG00256","COG0287","Prephenate dehydrogenase",0.77482,0.005047,0.802177,0.005275,0.721502,0.002174]
["MA4607","G","arCOG01087","COG0149","Triosephosphate isomerase",2.070954,1.2E-005,1.227114,0.007576,1.632703,0.000123]
["MA4608","C","arCOG00104","COG1795","Formaldehyde-activating enzyme nesessary for methanogenesis",2.678164,1E-006,1.455694,0.000828,2.086865,6.9E-005]
["MA4616","N","arCOG00891","COG0084","Tat protein secretion system quality control protein TatD (DNase activity)",1.427931,1E-006,1.037901,0.000966,1.203141,0.000297]
["MA4632","R","arCOG00995","COG1549","Predicted RNA-binding protein, contains uracil-DNA-glycosylase-like and PUA domains",1.037621,0.000666,0.835478,0.001954,0.921848,0.001037]
["MA4633","J","arCOG00833","COG0456","Ribosomal protein S18 acetylase RimI and related acetyltransferases",1.088098,0,0.620647,0.004399,0.974359,0.00098]
["MA4635","L","arCOG04281","COG0358","DNA primase (bacterial type)",1.447748,0.001955,1.102123,0.00718,1.188579,0.000297]
["MA4642","S","arCOG03208","COG4744","Uncharacterized protein",-1.363306,0,-0.760922,0.004332,-0.810275,0.00133]
["MA4649","K","arCOG00610","COG2524","Predicted transcriptional regulator, contains C-terminal CBS domains",2.11665,1.8E-005,1.35618,0.001155,1.673516,0.000152]
["MA4650","T","-","COG3448","CBS-domain-containing membrane protein",2.686328,1.5E-005,1.191172,0.009727,2.105642,0.000123]
["MA4651","K","arCOG00610","COG2524","Predicted transcriptional regulator, contains C-terminal CBS domains",1.987917,0.001133,1.30088,0.004728,1.563301,0.000186]
["MA4654","J","arCOG01564","COG3276","Selenocysteine-specific translation elongation factor",1.191163,0.000207,0.894202,0.006181,1.030856,0.000676]
["MA4659","R","arCOG01043","COG1931","Predicted RNA binding protein with dsRBD fold, UPF0201 family",1.56067,0,1.085183,0.0001,1.299089,0.000226]
["MA4660","H","arCOG01045","COG0237","Dephospho-CoA kinase",0.896194,0.000869,0.835447,0.006825,0.80849,0.001514]
["MA4671","T","arCOG02386","COG2204","DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains",-1.153466,0,-0.563045,0.008952,-0.678774,0.002376]
["MA4672","K","arCOG04341","COG1996","DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger",4.399004,0,1.277991,0.007609,3.308758,0]
["MAt4689","-","-","-","-",2.976054,0,1.414057,0.002709,2.275955,6.9E-005]
["MAt4690","-","-","-","-",4.974195,0,1.600841,0.000369,3.733046,0]
["MAt4700","-","-","-","-",5.23293,0,1.306274,0.003754,3.917503,0]
["MAt4715","-","-","-","-",5.416072,0,1.315928,0.005875,4.025327,0]
["MAt4735","-","-","-","-",1.2836,0.000283,0.838926,0.007833,1.105708,0.005298]

{"sheet":"edgeR","index":4,"n_rows":1137,"n_cols":11,"rows_kept":1137,"cut":false,"hidden":false,"merged":[]}
["Gene Locus","Log2FC MeOH/Ace","P-value","Gene Locus","Log2FC MeOH/TMA","P-value","Gene Locus","Log2FC TMA/Ace","P-value",null,"Key"]
["MA2536",-2.93379226584499,9.9869938852069E-022,"MA0527",-7.89374789435531,1.13678034719515E-024,"MA2536",-3.2006437590912,4.36182850719527E-021,null,"p-val < 0.0001"]
["MA1616",-7.05800802994505,2.57600801991361E-020,"MA0529",-7.5114756551772,4.34911145430247E-024,"MA0146",5.23007052214025,6.9328874359041E-018,null,"p-val < 0.001"]
["MA1617",-7.36879112589601,3.7385087101896E-019,"MA0528",-7.62152882452306,7.34715776707683E-024,"MA0532",7.4046525094953,6.39422225632322E-017,null,"p-val < 0.005"]
["MA4008",-7.22561426905277,3.52010887641547E-017,"MA0532",-6.97810118300361,3.05438044249768E-022,"MA0529",7.26868043644263,2.73317219694278E-016,null,"p-val < 0.01"]
["MA2925",-5.52429238836556,8.10492904462374E-017,"MA0859",-6.36923094842707,1.34603777210318E-019,"MA0528",7.28111156476202,7.0101135045474E-016]
["MA4634",-6.69016651756835,1.46676326332415E-016,"MA0144",-6.24175472713605,1.23098668675322E-018,"MA0527",7.25796026320576,1.20160031830165E-015]
["MA3606",-4.38591313586024,2.87617242248157E-016,"MA0531",-6.44636778176941,2.73024004811148E-018,"MA0835",3.59516255030317,2.13975836559305E-015]
["MA1568",-4.92018529655442,3.83594221281295E-016,"MA0145",-6.28949721593395,3.07050018812854E-018,"MA4194",5.68164690432143,3.08672779128028E-015]
["MA0887",-5.2741784594972,5.10926929351095E-016,"MA0530",-6.10058902206749,1.07029860909697E-017,"MA0531",7.22441721166747,5.35250865192244E-015]
["MA1615",-4.97911583630427,5.70302167222314E-015,"MA4384",-6.50455391878327,5.42901964124517E-016,"MA3130",4.5324116126325,7.43240112452697E-015]
["MA1432",-3.86113822544279,2.03049532762034E-014,"MA0146",-3.80036413929186,1.62730102670833E-015,"MA0859",6.59097928122367,1.44412170501025E-014]
["MA1690",-2.05999731891299,3.02037517271164E-014,"MA0143",-3.79254688984133,2.74683354162887E-013,"MA1690",-2.23740023573336,4.3575274518911E-014]
["MA1012",-3.31595638617422,3.8911264904114E-014,"MA4386",-3.99557774231856,3.60390096991155E-012,"MA0530",6.60650130467289,5.53601681887172E-014]
["MA1364",-4.65771747089698,5.32033821143079E-014,"MA4388",-6.61777690841245,6.23615137356604E-012,"MA0833",3.64299905394826,7.03593064999492E-014]
["MA3864",-3.47911074967818,5.61433649587225E-014,"MA0858",-4.20084805879522,6.69382264531894E-012,"MA4008",-7.16582539916912,8.7251045962472E-014]
["MA3408",-4.11118562707951,8.45753587246805E-014,"MA1465",-6.37386676133738,2.18684027015838E-011,"MA1616",-5.99777743596966,2.37141278563534E-013]
["MA3860",-3.77732083008946,1.28134480502796E-013,"MA0785",-6.2972088646706,7.85811344930685E-011,"MA4379",4.3144550559409,5.42283616393053E-013]
["MA2985",-3.73326105846334,1.36704029463738E-013,"MA0857",-3.42254712371512,8.80236726766875E-011,"MA2925",-5.27276085228525,6.11834567903007E-013]
["MA0247",-4.76933214580186,1.71365101910157E-013,"MA1349",-4.77237462353966,1.27463334907454E-010,"MA1617",-6.37192588414032,6.54897885514167E-013]
["MA0964",-2.54674065227928,2.19875246570131E-013,"MA4385",-4.44193837716095,1.96048077928743E-010,"MA1500",3.6649375770169,8.3839452367179E-013]
["MA3862",-3.90483891363412,2.38520817677752E-013,"MA4387",-5.19698311896416,7.2983623487084E-010,"MA0832",3.44405237987634,1.25752547970504E-012]
["MA2984",-3.52234268904548,3.60794583803697E-013,"MA0141",-2.73949429255309,1.79173146962049E-009,"MA1507",4.23114715380864,1.28550390847151E-012]
["MA2923",-3.4660869298821,3.76873364672377E-013,"MA1453",-4.31960549670547,2.58492771052237E-009,"MA0304",2.98644365445415,2.67691566775255E-012]
["MA2267",-2.39718294080691,9.79248861919948E-013,"MA3738",-4.00950486878527,4.15502082076986E-009,"MA4217",3.4904695348888,3.14534292567014E-012]
["MA3607",-4.62447814309147,1.39917986074398E-012,"MA0308",-1.97638215144407,5.28441016976267E-009,"MA3589",2.92395549587195,5.78683186202143E-012]
["MA3865",-3.54463683573731,1.58170961827809E-012,"MA2988",-2.31358108654436,5.74543843016421E-009,"MA4384",6.62981286429305,1.07277896184767E-011]
["MA3302",-5.3660996762721,1.98334142975257E-012,"MA1619",-4.40730689355247,1.1667690164507E-008,"MA0834",3.43633679176694,3.03625259055549E-011]
["MA2435",-2.34855884249438,2.66903291519451E-012,"MA1445",-3.35179679911387,1.54812250517773E-008,"MA4218",3.73756857880133,3.97105943579363E-011]
["MA1574",-3.58827629408666,3.05754246960928E-012,"MA2964",-2.35256209987893,1.98112943252556E-008,"MA4671",-3.66284575753436,4.58860939069757E-011]
["MA3863",-3.32563631730299,5.27164027410288E-012,"MA1419",-1.7093689709439,2.37404314632568E-008,"MA3382",3.65324673411197,5.74105612521823E-011]
["MA3861",-3.73376533960736,6.06271598915661E-012,"MA0028",-4.30780192261564,3.10557230303038E-008,"MA1143",2.36995755071991,7.09099962778003E-011]
["MA0215",-4.33487258417138,6.48540319346034E-012,"MA2986",-1.7663518353804,3.10767030247782E-008,"MA1568",-4.22173718878683,9.73764846865817E-011]
["MA3152",-4.07047591146467,6.74268389881437E-012,"MA0154",-2.24668842708051,3.17523323376143E-008,"MA1501",3.86595609089629,9.8178374852209E-011]
["MA2441",-3.14652938623036,7.03710583654986E-012,"MA0849",-2.23756174840918,3.56672922252298E-008,"MA4220",3.75054808721265,9.94024748572879E-011]
["MA0133",-3.68707315398817,7.22655532192446E-012,"MA0237",-2.98541478803211,1.10268840553663E-007,"MA3733",3.75994190981611,1.15873543206753E-010]
["MA1431",-3.1455282586524,7.52030674503772E-012,"MA3696",-2.37414508350645,1.47911475104557E-007,"MA1488",2.32195335965401,2.14887590519159E-010]
["MA1011",-3.39145120612942,7.78761030999605E-012,"MA4044",-1.50499574341587,1.5973005949504E-007,"MA4634",-5.45723885005459,2.24696966932296E-010]
["MA3246",-3.45241445055461,1.00058714127617E-011,"MA2989",-2.29293282627556,2.24820946212669E-007,"MA0305",2.6619846956436,2.47521859043536E-010]
["MA4568",-2.52186599363028,1.04638026194955E-011,"MA3417",-2.62972387654283,2.4372419494968E-007,"MA4044",2.12975910668241,2.52938625053266E-010]
["MA0134",-2.86316050839229,2.13238470864819E-011,"MA4389",-2.62510187530222,2.48981822502571E-007,"MA0143",3.89874961426566,2.97213300859975E-010]
["MA4567",-2.06575930880826,2.62608232381039E-011,"MA0663",-2.19194855153436,3.31261156206258E-007,"MA1503",3.38577654237214,2.98087082697153E-010]
["MA1940",-2.70425118490106,3.12835310165305E-011,"MA1499",-2.55588514233017,3.48917747357751E-007,"MA2257",2.7744975505585,3.07980065104181E-010]
["MA3284",-3.01278703662899,3.40646118997292E-011,"MA0305",-1.78127796312957,4.13701264083184E-007,"MA2267",-2.29658543906664,3.40592328482282E-010]
["MA3130",3.62053372841444,3.68540546947137E-011,"MA3735",-2.77581707003102,7.27120309337952E-007,"MA2866",-2.35296035400134,4.08205269994025E-010]
["MA1735",-3.15908527695441,3.75290889520368E-011,"MA3141",-2.9324577959383,8.21128752801565E-007,"MA3916",2.86580377589853,4.47731752277166E-010]
["MA1654",-2.21112464754126,5.10226571557116E-011,"MA1504",-2.3328410690343,8.48490434326542E-007,"MA4386",4.33429832196566,4.47825338887848E-010]
["MA2299",-3.53079264253256,5.40274667055963E-011,"MA0309",-1.87446338397607,8.6986297233087E-007,"MA3522",1.83481698608714,4.56390433829826E-010]
["MA4200",-3.47547271115882,8.80649596327483E-011,"MA0304",-1.72621278213722,9.05603832509691E-007,"MA0858",4.63406503085917,5.01217544702436E-010]
["MA3482",-3.03562903340639,1.35555730816657E-010,"MA1143",-1.50666339922143,9.07488472465929E-007,"MA3368",-3.41161818635239,5.2824488752763E-010]
["MA3076",-2.59746489551184,1.48578225959905E-010,"MA4041",-1.87060122460981,9.22394948998216E-007,"MA1502",3.4415578842073,6.88090534794215E-010]
["MA1013",-2.98634673802559,1.50770882810149E-010,"MA2879",-1.83021580792718,1.04078719864248E-006,"MA1504",3.61481940540182,6.92653455878927E-010]
["MA1799",-2.60952411202885,1.53349106964392E-010,"MA1443",-2.39609973011124,1.13381213220433E-006,"MA0857",3.93746380777645,7.49519485375411E-010]
["MA3972",-3.11110998396417,1.67318875894318E-010,"MA2561",-2.3067557368401,1.18098940942711E-006,"MA0794",-2.65997105769342,7.79507789694032E-010]
["MA4569",-2.43797161623971,2.46252285415486E-010,"MA1501",-2.31160187599749,1.24574936754255E-006,"MA4219",3.43436805891707,8.0942762375648E-010]
["MA3420",-2.54592928676484,2.60009825940679E-010,"MA1780",-2.28529486119532,1.70213436329992E-006,"MA3731",3.23402888373622,9.70082703513557E-010]
["MA4565",-3.59735354880309,2.75461420408026E-010,"MAt4700",-3.13851643395611,1.77675188632959E-006,"MA1364",-4.09927500820254,1.06761212957494E-009]
["MA1711",-2.9923041281123,3.3277598139241E-010,"MA4329",-2.20098625851234,1.81220873159731E-006,"MA3706",2.29863413186817,1.1611405954506E-009]
["MA1998",-3.56302878958343,3.82452430827679E-010,"MA2990",-1.78278706416229,1.8470997563369E-006,"MA0307",2.79586700403355,1.17604570171373E-009]
["MA2866",-2.14582194861769,4.15703149140714E-010,"MA0307",-1.82015853226355,1.9096372178949E-006,"MA4413",3.1516046851477,1.37344025957521E-009]
["MA4268",-3.55783300076817,5.80156466093925E-010,"MA0936",-1.4105736029797,1.93752635001639E-006,"MA2441",-3.04495621413439,1.43459162168046E-009]
["MA0985",-3.06643938274475,6.16523647944316E-010,"MA2934",-2.55135118341226,1.96366270281682E-006,"MA0144",4.76039775390187,2.09979321014555E-009]
["MA3113",-3.09079398446394,6.26535630769065E-010,"MA1502",-2.15302237605105,1.98486384039689E-006,"MA0306",2.56522923625333,2.28775215401397E-009]
["MA0794",-2.40025499917917,9.58367902471753E-010,"MA1505",-2.18536453959156,2.1481071108364E-006,"MA2013",-2.67636599079398,2.43290248389814E-009]
["MA1303",-4.30359057517693,9.77347248770251E-010,"MA3734",-2.36878465627502,2.19824402961116E-006,"MA3550",-2.53954858506051,2.43419212367852E-009]
["MA1794",-2.65702983779182,1.23478020465402E-009,"MA4594",-1.5272442461578,2.22559944566265E-006,"MA0145",4.84174706951632,2.48517926728178E-009]
["MA0685",-3.56906832088497,1.35620566316788E-009,"MA0017",-2.38814531260251,2.35009512127368E-006,"MA3482",-3.10506785409591,2.60804986668582E-009]
["MA1658",-2.47471430924755,1.69155581863319E-009,"MA2430",-1.26161071608272,2.43013875390685E-006,"MA4388",7.06320764069447,2.91826186870363E-009]
["MA3611",-1.57192514588925,1.70217960875431E-009,"MA2935",-2.23423983467853,2.47500135558951E-006,"MA1431",-2.98108572397019,2.98206702641303E-009]
["MA0832",2.75786809070844,1.87899023889636E-009,"MA2715",-2.61790276612624,2.51383680809419E-006,"MA1506",3.71470572430539,3.12776931753863E-009]
["MA2560",-3.64094029185186,1.95861912730794E-009,"MA2717",-2.16219006656886,2.64508568000064E-006,"MA1619",5.88612285895714,3.17449153468863E-009]
["MA4572",-2.379963309807,2.1547675922933E-009,"MA3742",-1.6286870125012,3.07639514732081E-006,"MA0433",2.10373996315356,3.28261980049839E-009]
["MA0539",-3.36926582397129,2.22969747670109E-009,"MA0661",-1.715314284514,3.24179613970717E-006,"MA1505",3.32818481735286,3.77526060575465E-009]
["MA4194",3.87408949276809,2.28928627075538E-009,"MA0059",-2.4965455233861,3.48598607565129E-006,"MA1432",-3.19742685052037,4.06971317221281E-009]
["MA3368",-2.92898876968106,2.32168365532815E-009,"MA1500",-1.89292972438107,3.68888086121979E-006,"MA2988",2.7566140340537,4.91833495489205E-009]
["MA1552",-3.09209165744707,2.3346220787206E-009,"MA1506",-2.33088763893493,3.75161112212531E-006,"MA2992",2.39876691102286,4.92343856104037E-009]
["MA0477",-3.33572069207058,2.35443767209839E-009,"MA0155",-1.65382761076556,3.7546959639957E-006,"MA0308",2.31531097888404,5.38124631393085E-009]
["MA0536",-3.5571954999706,2.87019287978344E-009,"MA4593",-1.61411756459149,3.81485961293099E-006,"MA4380",2.12328424626757,5.4055682403599E-009]
["MA1593",-2.19564408568897,3.18410669701908E-009,"MA1488",-1.42692034965217,3.83337464747675E-006,"MA2438",-2.29992513059147,5.65673600081114E-009]
["MA1097",-3.47154234752914,3.69549413512981E-009,"MA1142",-1.71145481371093,3.84443268270875E-006,"MA4387",6.17407854597661,6.52568587167216E-009]
["MA1426",-1.90968808364223,3.85014994707014E-009,"MA4336",-2.29814384189795,3.94827860754414E-006,"MA2914",2.31477146583008,6.57459593692821E-009]
["MA3252",-2.59128231201963,4.26297315924975E-009,"MA1683",-1.26650184710948,4.07659976392781E-006,"MA2976",-1.92570980273671,7.05413245525665E-009]
["MA2410",-1.94318956069636,4.51782815340704E-009,"MA4152",-2.32669071357427,4.10356400077994E-006,"MA1615",-3.91973813099244,7.39033284311494E-009]
["MA2964",-2.52551459730755,4.64024580448844E-009,"MA0583",-1.39658800987603,4.21749406514797E-006,"MA3696",3.15201164168678,7.62095884421617E-009]
["MA3679",-2.59589508323961,4.66099694805531E-009,"MA4176",-1.58652215886903,4.26221435973556E-006,"MA0372",1.98894866314314,7.68199865723876E-009]
["MA4610",-3.16807889184406,5.25502503314433E-009,"MA0382",-1.40478311447181,4.45066758529155E-006,"MA4329",3.23819807001621,8.3020302404156E-009]
["MA0658",-2.42554467935147,5.32259882960046E-009,"MA3028",-2.60155837554215,4.76350552623817E-006,"MA2984",-3.00298204951534,1.00336495684019E-008]
["MA4671",-2.86153078383269,5.41000346729991E-009,"MA2987",-2.17082233956966,5.10693250795986E-006,"MAt4689",2.72498855758,1.06013106805528E-008]
["MA0807",-2.61830905731975,6.54933731174673E-009,"MA0306",-1.63756615862298,5.25787609412413E-006,"MA1309",-2.50111374123511,1.083797227149E-008]
["MA3075",-2.36666973627251,6.63293628060355E-009,"MA0825",-2.5244364775063,5.55121068461943E-006,"MA3302",-4.72845164182961,1.13675261086174E-008]
["MA4665",-2.53092285262474,6.78606946745847E-009,"MA0153",-1.92874688810105,6.40229915100489E-006,"MA2986",2.12607759663043,1.15512413754445E-008]
["MA1659",-2.29123861726109,7.35635014507396E-009,"MA4040",-1.53939796058256,6.42691803510677E-006,"MA1574",-3.18761358188248,1.20402170992314E-008]
["MA2814",-2.65278579859142,7.43535430961665E-009,"MA1050",-2.15820629726243,6.52125670113914E-006,"MA3246",-3.14950910116814,1.24437382235347E-008]
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{"sheet":"DESeq2","index":5,"n_rows":758,"n_cols":11,"rows_kept":758,"cut":false,"hidden":false,"merged":[]}
["Gene Locus","Log2FC MeOH/Ace","P-value","Gene Locus","Log2FC MeOH/TMA","P-value","Gene Locus","Log2FC TMA/Ace","P-value",null,"Key"]
["MA2536",-2.23214128929986,1.49591624846729E-030,"MA0527",-7.26617812570155,1.94377923376307E-150,"MA0527",6.82326885552567,7.47446635601283E-101,null,"p-val < 0.0001"]
["MA0455",4.1298992294526,2.55095584980341E-026,"MA0532",-6.31444076154049,2.31274927882233E-112,"MA0532",5.91576036246121,5.17700959661722E-075,null,"p-val < 0.001"]
["MA0457",4.02370011246614,5.41706662295973E-026,"MA0144",-5.79603182484151,5.54414115690944E-091,"MA0144",5.52238509704306,3.62510552243576E-063,null,"p-val < 0.005"]
["MA0456",3.93669788033281,1.84829684329501E-023,"MA0528",-6.23614043547531,1.38057394862057E-089,"MA0528",5.87246856938746,1.81071000688028E-062,null,"p-val < 0.01"]
["MA4194",3.2749243457355,1.59107521310929E-021,"MA0529",-6.23863629495632,4.81114826763318E-085,"MA0529",5.83565690059274,3.69980777801845E-059]
["MA3860",-3.07342033255825,3.09510869400027E-015,"MA0531",-5.50050255932252,1.65568407416986E-079,"MA0531",5.24840515025712,1.14527025096154E-055]
["MA4567",-1.4342134032202,1.14361636308261E-012,"MA0145",-5.3545330024432,5.73422940438995E-065,"MA0145",5.20430578738562,1.98477367749288E-048]
["MA4119",0.731909232313112,2.12746270296166E-012,"MA0143",-3.13326721079165,2.14278244517458E-036,"MA0146",4.02736503753856,7.20644059546292E-025]
["MA3862",-2.81690669792102,2.43385704871249E-011,"MA0457",4.12447631920028,6.78083431212078E-029,"MA2536",-2.28391739060696,1.42900332274242E-023]
["MA3667",-1.36845084878549,2.60061477093747E-011,"MA0455",4.07423069570017,2.77557310784516E-027,"MA0143",2.90310974453258,7.01178541147264E-023]
["MA1690",-1.3773058444841,4.09117671580886E-011,"MA0456",4.00229420044558,1.01452154073191E-025,"MA4194",3.42072509095105,1.44763534097099E-019]
["MA3861",-2.69050457205954,4.10728731517696E-011,"MA0146",-3.19976828159243,7.43795233600508E-019,"MA0141",2.36878445203648,1.16383591978059E-015]
["MA1616",-2.14475856634005,1.2850471550913E-010,"MA0858",-1.60914513536672,9.06497652515212E-016,"MA1497",2.71419189987191,1.91529679164946E-011]
["MA3864",-2.46307036273316,2.29213154721649E-010,"MA0141",-1.85718819557797,6.39752441288995E-013,"MA3130",2.77388048868543,2.38223662607766E-011]
["MA4391",2.42055311678142,2.63162802036186E-010,"MA4393",1.74212710042367,3.50524532140452E-010,"MA4430",2.78198897283474,5.57428053825477E-011]
["MA4568",-1.80850651321172,2.63162802036186E-010,"MA4391",2.32542985471484,9.24911077941791E-010,"MA0304",2.46224276218707,9.62784459695358E-011]
["MA1632",-0.815360019448273,3.5993060712118E-010,"MA2988",-2.19260348771298,1.90456013703912E-009,"MA2561",1.87656651183401,9.67022181804264E-010]
["MA0887",-1.76547105077546,4.74322849558989E-010,"MA0154",-1.31879681201397,8.32738899238174E-009,"MA0305",2.3629030136734,1.34665002920598E-009]
["MA1012",-2.3195800443092,8.709508324636E-010,"MA0150",-0.958973980932604,1.01224707196204E-008,"MA3733",2.64683477623629,1.34665002920598E-009]
["MA1633",-1.03990610227718,1.26472201884791E-009,"MA2990",-1.89186195524536,2.88526277545972E-008,"MA1495",2.32150889312205,2.01973237247096E-009]
["MA3263",0.911353027514758,1.47172575262526E-009,"MA0825",0.792128107422066,3.24228054529212E-008,"MA1496",2.43389520072564,5.40775821365296E-009]
["MA1617",-2.06579349203578,1.66214421966996E-009,"MA2561",-1.48199228961106,3.39457243064196E-008,"MA1690",-1.39891263264333,2.67399972832397E-008]
["MAt4735",1.51194941677052,2.00324957117387E-009,"MA2989",-2.14363738983342,5.56461888229452E-008,"MA0211",1.22663259114726,2.68073688115521E-008]
["MA4569",-1.6343232979906,4.87747791584592E-009,"MA2193",-0.858023924133247,1.38968468075024E-007,"MA0858",1.39215316609583,3.0502981983385E-008]
["MA1783",1.65068596249147,1.5377780897503E-008,"MA4176",-1.76326282492758,1.57872051573271E-007,"MA0307",2.2382232710461,3.49781808305982E-008]
["MA3522",1.20763971498139,2.9399391070445E-008,"MA0309",-1.84514268987228,4.49348497414366E-007,"MA4262",1.94113437980393,3.95058380346814E-008]
["MA1497",2.07210406094938,5.89548179424979E-008,"MA2987",-2.08122624778669,5.03230869392472E-007,"MA0309",2.18733167495692,5.11011877394638E-008]
["MA2925",-0.98988500489477,7.43458311149448E-008,"MA4392",1.94054942617181,5.24932439907849E-007,"MA4379",2.44099639028218,5.32400032114512E-008]
["MA0755",-1.16034949500629,1.85708275570973E-007,"MA0307",-1.84667549293989,6.72051381577788E-007,"MA3522",1.38603119638837,6.77031606030867E-008]
["MA3044",-0.822434638613908,1.85708275570973E-007,"MA3931",-1.13930784121832,8.53024110602472E-007,"MA0150",1.06971966923324,9.78603078862133E-008]
["MA3863",-2.07687981585472,2.6674224137716E-007,"MA1285",-1.07117133860431,1.01810990410811E-006,"MA4043",1.97266936491418,1.37642524499574E-007]
["MA4572",-1.73414366601779,3.22738840746512E-007,"MA1419",-1.42281639484935,1.04820901636778E-006,"MA1490",1.90819528556311,1.52749662917459E-007]
["MA3865",-2.09293390252839,3.65258566748814E-007,"MA4175",-1.16883807470367,1.1012050596923E-006,"MA1143",1.68257255892945,1.57035731873122E-007]
["MAt4705",1.82293727326456,3.95094548801351E-007,"MA0305",-1.73187111913505,1.803445824335E-006,"MA0942",1.87090090587255,1.67047268339656E-007]
["MA4430",2.08910874266592,4.5640560663714E-007,"MA2991",-1.82209621217156,4.80484176049647E-006,"MA1108",2.23842234423166,1.67047268339656E-007]
["MA4379",2.15426548091482,9.10891936892355E-007,"MA3250",-1.17677431425372,4.80484176049647E-006,"MA4567",-1.28719998575231,1.67047268339656E-007]
["MA1042",0.669220465793369,1.26940573035757E-006,"MA4256",0.777788548106178,1.01181131382655E-005,"MA3631",2.06295143921776,1.70313121728376E-007]
["MA3277",-0.850068209125685,1.26940573035757E-006,"MA3553",-0.932074315815926,1.34888132411948E-005,"MA0154",1.41226463122385,1.86737748850444E-007]
["MA4393",1.41217428757772,1.26940573035757E-006,"MA2761",-0.915365383051634,1.78677496700571E-005,"MA4245",1.89617109838148,2.22097122690822E-007]
["MA3606",-2.00964303601553,2.08700756584107E-006,"MA0304",-1.5559980407021,2.22387835676387E-005,"MA0433",1.50515535595214,2.32236111896399E-007]
["MA4008",-0.753205067326213,2.14589559338949E-006,"MA2533",-0.861273721775299,2.22387835676387E-005,"MA0308",1.97894785608886,2.54051883849346E-007]
["MA4392",1.85552163919823,2.64082933196097E-006,"MA3939",-0.768181057938658,2.22387835676387E-005,"MA0835",1.99766014388735,2.54051883849346E-007]
["MA1011",-1.95961525183676,2.71153606443622E-006,"MA3941",0.563961186169774,2.22387835676387E-005,"MA4329",2.26660497091689,2.74043675468891E-007]
["MA1432",-1.15620332606508,2.71153606443622E-006,"MA4390",1.31450896758641,2.22387835676387E-005,"MA1498",2.25409969746326,3.00650969247775E-007]
["MA3130",1.89312786480436,3.43315986811023E-006,"MA4119",0.474462123334598,3.48622470450111E-005,"MA0599",2.11340460764637,4.60033479741887E-007]
["MA3930",-0.670489204814615,3.43315986811023E-006,"MA3930",-0.613803162404222,4.17996695012721E-005,"MA2594",-1.00599939992785,4.60033479741887E-007]
["MA1678",-0.469968728916269,3.6412189062835E-006,"MA0155",-1.32529674841356,4.20444964431078E-005,"MA0010",2.09678200379775,4.76668822885904E-007]
["MA3611",-0.847943829007674,3.64765793148202E-006,"MA3132",0.896473102279576,4.71513318456237E-005,"MA2989",2.17609642412213,4.76668822885904E-007]
["MA4634",-1.85831281200368,3.76991960385062E-006,"MA2760",-0.575472418229841,6.69491356916805E-005,"MA4261",1.86829356707598,5.1968723236156E-007]
["MA2435",-0.936833478596975,4.28506368809292E-006,"MA3932",-1.02603188762171,6.97244321420735E-005,"MA4272",1.70429442850562,5.25084372871069E-007]
["MA2267",-1.06976537847284,4.71781570577859E-006,"MA0308",-1.43260585914044,8.4254176896519E-005,"MA3791",2.13702437214469,5.3973268753673E-007]
["MA0334",1.01239811239308,4.91619404781674E-006,"MA0740",0.6227743077714,8.4254176896519E-005,"MA1255",2.15672790927741,7.43488804691588E-007]
["MA0923",1.83015980150049,6.32333413354948E-006,"MA3746",0.818257823617532,0.00010354598307849,"MA4044",1.72688493475375,7.43488804691588E-007]
["MA2013",-0.576460357344049,6.32333413354948E-006,"MA2986",-1.45718483815839,0.000125335537958179,"MA2988",2.04663827214591,7.69487202864825E-007]
["MAt4685",1.71693477423357,8.05990314547744E-006,"MA1188",0.755003081568631,0.000135929794992529,"MA0949",2.10417177764924,1.03213480040688E-006]
["MA1495",1.62414448906845,8.63715380067413E-006,"MA3167",-1.053288206037,0.000135929794992529,"MA4413",2.16368109319759,1.30697535342E-006]
["MA2150",-0.728431398134946,9.55187717772944E-006,"MA0259",0.562889756532249,0.000158258277115522,"MA0086",2.18176311940305,1.31626712648051E-006]
["MA0259",0.622952205026894,1.15176259680522E-005,"MA0306",-1.49384613461293,0.000172893213783044,"MA1500",2.07725282684001,1.31626712648051E-006]
["MA1964",1.27185719856662,1.15176259680522E-005,"MA2964",-1.50630123312574,0.000182417726160274,"MA1783",1.64161628546811,1.35830172552336E-006]
["MA2152",-0.911009579113924,1.15176259680522E-005,"MA3198",-1.41351546187679,0.000215185985996814,"MA0890",-0.985138369643115,1.41042956539492E-006]
["MA0010",1.71035598401682,1.27709696708314E-005,"MA3739",-1.16001528659102,0.000215185985996814,"MA0306",1.97315405491057,1.61785005846606E-006]
["MA2308",-0.654402998223201,1.44260702657977E-005,"MA4139",0.581131956778919,0.000215185985996814,"MA4176",1.82827596083603,1.61785005846606E-006]
["MA3437",0.871052722741108,1.63663161366872E-005,"MA0692",0.435581888913035,0.000244510301606318,"MA2987",2.1230205993394,1.67406956979591E-006]
["MA2076",-0.589076605294756,2.14312178745938E-005,"MA4177",-0.877142550410241,0.000311077128803359,"MA0887",-1.60574703668253,1.70452146764079E-006]
["MA2982",-1.20258746019765,2.14312178745938E-005,"MA4438",0.747048053185575,0.000328613609633131,"MA2990",1.85684301042888,1.70785205495036E-006]
["MA0646",1.79456739612105,2.26426307975058E-005,"MA4250",0.666255310184756,0.000336742973845434,"MA3696",1.60205068856354,1.70785205495036E-006]
["MAt4690",1.78542791581682,2.35871332828321E-005,"MAt4708",1.32608435865866,0.000382527551504927,"MA1507",2.17258875009125,1.8285578538769E-006]
["MA1013",-1.72627286418317,2.72354519798976E-005,"MA0355",1.05940036108373,0.000385969900632413,"MA2603",-0.785548794693818,1.8285578538769E-006]
["MA1568",-1.15909787005119,3.0749044177676E-005,"MA1176",0.595669664803675,0.000400010288483706,"MA1080",2.0536515564235,1.83906520313259E-006]
["MA3932",-1.04953719971321,3.18589219487056E-005,"MA0211",-0.726020499668068,0.000418967569235211,"MA0646",2.07996978807428,2.14264447633958E-006]
["MA1654",-0.577107677155778,3.4433006527248E-005,"MA4466",0.706572348338627,0.000491041680564312,"MA0596",2.03162830952956,2.40156441391643E-006]
["MA0964",-1.05098909340443,3.95158948138981E-005,"MA0831",0.531956157831874,0.000520131518133631,"MA2604",-1.02838120499444,2.68095549643034E-006]
["MA0006",0.953595806839254,4.10530533395093E-005,"MA2969",-0.599086352182452,0.000520544178098729,"MA1964",1.52582083091205,2.85641861574794E-006]
["MA0835",1.47938506084734,4.67639332474847E-005,"MA4146",0.616767400356445,0.00054438244620913,"MA0155",1.64533672442739,3.0424403843481E-006]
["MA1735",-0.967511132692727,5.44544452615108E-005,"MA1978",-0.93882759367773,0.00056718575461012,"MA0889",-1.11283742178707,3.86529348878675E-006]
["MA2604",-0.77799481869267,5.44544452615108E-005,"MA4215",0.911043353708999,0.000579830972791046,"MA1110",1.96781868964657,3.86529348878675E-006]
["MA2850",-0.762926877075749,5.66390753035882E-005,"MA2746",-0.657906348035185,0.000601399114248692,"MA2533",1.06434642283501,3.86529348878675E-006]
["MA4120",0.93320989061089,5.93907223631242E-005,"MA4068",-0.630464619581046,0.00066642154930648,"MA0833",1.98747282776732,4.0003575136539E-006]
["MA1615",-1.03029136971539,6.07435072289594E-005,"MAt4734",1.24914349628118,0.000697862362272668,"MA0034",1.91116430958548,4.10071232359983E-006]
["MA2434",-0.50316426995172,6.09461351531016E-005,"MA4044",-1.13703713231252,0.000731921688011709,"MA1141",1.76085411340767,4.3337572411548E-006]
["MA3631",1.48728218056491,6.55440348844385E-005,"MA2963",-0.53306278181513,0.00076048413080603,"MA3793",1.93672368004604,4.59320024136686E-006]
["MA0034",1.56593968268079,6.6559591751385E-005,"MA4475",0.910831596917049,0.00076048413080603,"MA1710",1.90405002912281,5.22119406706033E-006]
["MA0833",1.64778868768346,6.88644821211975E-005,"MA2110",-0.773994501002906,0.000799509388880658,"MA1087",1.81473419617548,5.33740520172436E-006]
["MAt4708",1.42763014080485,7.19608106261218E-005,"MA2430",-0.715620459288787,0.000803947929814154,"MA2873",-0.790502615587932,5.35647154830552E-006]
["MA3408",-0.979167406925586,7.58412927538881E-005,"MA1654",-0.495398454057746,0.000882348532389167,"MA4041",1.8128820453641,5.49943562651008E-006]
["MA0490",0.478484389349845,7.84959213788577E-005,"MA2011",-0.680524220316571,0.00104861650650864,"MA0832",2.0243230195327,5.69152979544172E-006]
["MA3539",-0.629847506985604,7.84959213788577E-005,"MA0650",0.516602269409331,0.0011758614248754,"MA0792",-0.66030681620099,6.05918819295216E-006]
["MA3931",-0.943130155028117,8.12785655646007E-005,"MA0752",-0.894257232961369,0.00122650019002375,"MA2991",1.93452346249731,6.30409999406137E-006]
["MA0002",1.18281537189401,9.18535936404927E-005,"MA0018",-0.919761603589337,0.00132182059800816,"MA4259",1.7469752662842,6.83532478966676E-006]
["MA2985",-1.39554985506223,9.45964321610176E-005,"MA0710",-1.41398115235799,0.00132182059800816,"MA2257",1.5841687012497,7.12052010662319E-006]
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["MAt4734",1.36956119255988,0.000101523592104122,"MA0963",-0.696096350239867,0.00137049098749256,"MA1109",1.99782403851386,8.78285671695625E-006]
["MA2284",-0.652857160961093,0.000103693856823865,"MA4505",0.601415154705624,0.00137049098749256,"MA1671",1.95355114751658,9.49069539467238E-006]
["MA3171",-0.724277452797881,0.000114729037806152,"MA3252",-0.710566490342226,0.00138673276689663,"MA0864",1.36128380586678,1.09448376654494E-005]
["MA3576",0.788343031825481,0.000119501095995891,"MA0786",0.936268148267519,0.00143773424110378,"MA1074",1.85293629761836,1.1894359825646E-005]
["MA2584",-0.776554662971501,0.000128509173930628,"MA0799",0.727241488754909,0.00143773424110378,"MA1504",1.86241450905774,1.20890854582793E-005]
["MA1364",-0.962062363251902,0.000131528557556066,"MA3650",0.506207623157174,0.00143773424110378,"MA0923",1.89434067097852,1.2753525676878E-005]
["MA2860",-0.764146670639602,0.000132734259784351,"MA4083",0.596112960791279,0.00143773424110378,"MA4258",1.55280065703305,1.2753525676878E-005]
["MA2964",-1.51117865268966,0.000138454515286507,"MA0901",0.750577652136244,0.00148524978731236,"MA4042",1.7745294058793,1.43170834193349E-005]
["MA1496",1.5597650980588,0.000147608918036983,"MA3344",-1.00321162250444,0.00151650002293944,"MA2193",0.849036051864732,1.44065790143469E-005]
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{"sheet":"PoissonSeq","index":6,"n_rows":2597,"n_cols":11,"rows_kept":2597,"cut":false,"hidden":false,"merged":[]}
["Gene Locus","Log2FC MeOH/Ace","P-value","Gene Locus","Log2FC MeOH/TMA","P-value","Gene Locus","Log2FC TMA/Ace","P-value",null,"Key"]
["MA3302",-3.84204603642524,5.06116742395994E-005,"MA0527",-5.58465395558434,0,"MA4194",4.08789871870964,5.10204081630484E-006,null,"p-val < 0.0001"]
["MA4194",2.58977893672391,5.34428521494113E-005,"MA0529",-5.35983771300343,0,"MA1494",2.77157797909985,1.22448979591316E-005,null,"p-val < 0.001"]
["MA1303",-3.1226312216716,6.70744494929498E-005,"MA0531",-4.62566363563225,0,"MA1619",4.26670509956603,1.87925170067228E-005,null,"p-val < 0.005"]
["MA1615",-3.58778278542897,8.33275078640918E-005,"MA0528",-5.44666704822603,0,"MA0531",5.18092655349193,2.08333333332448E-005,null,"p-val < 0.01"]
["MA2984",-2.56718195543671,9.78329255501649E-005,"MA0532",-4.96248390190229,0,"MAt4715",2.05820034449465,2.23639455781362E-005]
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