Hits Accession Desription Mass Seq Score Cov SameSets Spectrum Unique Spectrum Peptide Unique Peptide DP9-VS-DP3@Ratio@set1,DP9_1_114-VS-DP3_1_113 DP9-VS-DP3@Ratio@set1,DP9_2_117-VS-DP3_2_115 DP9-VS-DP3@Ratio@set1,DP9_3_121-VS-DP3_3_118 DP9-VS-DP3@QuantNumber@set1,DP9_1_114-VS-DP3_1_113 DP9-VS-DP3@QuantNumber@set1,DP9_2_117-VS-DP3_2_115 DP9-VS-DP3@QuantNumber@set1,DP9_3_121-VS-DP3_3_118 DP9-VS-DP3@Sig@set1,DP9_1_114-VS-DP3_1_113 DP9-VS-DP3@Sig@set1,DP9_2_117-VS-DP3_2_115 DP9-VS-DP3@Sig@set1,DP9_3_121-VS-DP3_3_118 DP9-VS-DP3@Mean DP9-VS-DP3@SD Accession NCBInr Identity NCBInr E_Value NCBInr Accession NCBInr Description Uniprot_Swissprot Identity Uniprot_Swissprot E_Value Uniprot_Swissprot Accession Uniprot_Swissprot Description Uniprot_Tremble Identity Uniprot_Tremble E_Value Uniprot_Tremble Accession Uniprot_Tremble Description Protein_or_Domain COG Identity COG E-Value COG_ID COG Function-Description COG Code COG Functional-Categories KEGG(ko_id|rank|evalue|score|identity|ko_definition) GO Biological_Process GO Molecular_Function GO Cellular_Component 1 tr|F8VYK9|F8VYK9_HUMAN Insulin-like growth factor-binding protein 6 OS=Homo sapiens GN=IGFBP6 PE=4 SV=1 27874 MTPHRLLPPLLLLLALLLAASPGGALARCPGCGQGVQAGCPGGCVEEEDGGSPAEGCAEAEGCLRREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLPARAPAEENPKESKPQAGTARPQDVNRRDQQRNPGTSTTPSQPNSAGVQDTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSSSCPTGSSG 178 27.7 1 10 10 5 5 0.89 1.31 0.984 7 8 9 - * - 1.061333333 0.22042081 tr|F8VYK9|F8VYK9_HUMAN 100 2.00E-14 gi|145579863|pdb|2JM2|A Chain A, Structure Of The N-Terminal Subdomain Of Insulin-Like Growth Factor (Igf) Binding Protein-6 And Its Interactions With Igfs 99.17 1.00E-94 sp|P24592|IBP6_HUMAN Insulin-like growth factor-binding protein 6 OS=Homo sapiens GN=IGFBP6 PE=1 SV=1 100 1.00E-94 F8VYK9 F8VYK9_HUMAN Insulin-like growth factor-binding protein 6 OS=Homo sapiens GN=IGFBP6 PE=4 SV=1 - - - - - - - K10138|1|4e-11|68.6|cfa:100855619|insulin-like growth factor-binding protein 3 GO:0008285//negative regulation of cell proliferation;GO:0001558//regulation of cell growth;GO:0007165//signal transduction GO:0005520//insulin-like growth factor binding GO:0005576//extracellular region 2 tr|A0A096LP62|A0A096LP62_HUMAN Inter-alpha-trypsin inhibitor heavy chain H5 OS=Homo sapiens GN=ITIH5 PE=4 SV=1 92484 MRNYDSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLTVCFNIDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERSYLEITPSRVILDGGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYKKPAPFQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPLLLQVGEGPEAVLTVKGHQVPVVWKQRKIYNGEEQIDCWFARNNAAKLIDGEYKDYLASHPFDTGMTLGRGMSREL 73 7.8 5 6 6 5 5 1.566 1.395 2.19 3 3 3 - - * 1.717 0.418457883 tr|A0A096LP62|A0A096LP62_HUMAN 100 0 gi|119606788|gb|EAW86382.1| inter-alpha (globulin) inhibitor H5, isoform CRA_d [Homo sapiens] 99.72 0 sp|Q86UX2|ITIH5_HUMAN Inter-alpha-trypsin inhibitor heavy chain H5 OS=Homo sapiens GN=ITIH5 PE=2 SV=2 100 0 C9J2H1 C9J2H1_HUMAN Inter-alpha-trypsin inhibitor heavy chain H5 OS=Homo sapiens GN=ITIH5 PE=4 SV=1 alr4412 82.4 3.00E-15 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R General function prediction only ; K05316|1|1e-12|76.3|aga:AgaP_AGAP009598|voltage-dependent calcium channel alpha-2/delta, invertebrate - - 3 tr|A7LFP5|A7LFP5_HUMAN Beta-mannosidase OS=Homo sapiens GN=MANBA PE=2 SV=1 114251 MRLHLLLLLALCGAGTTAAELSYSLRGNWSICNGNGSLELPGAVPGCVHSALFQQGLIQDSYYRFNDLNYRWVSLDNWTYSKEFKIPFEISKWQKVNLILEGVDTVSKILFNEVTIGETDNMFNRYSFDITNVVRDVNSIELRFQSAVLYAAQQSKAHTRYQVPPDCPPLVQKGECHVNFVRKEQCSFSWDWGPSFPTQGIWKDVRIEAYNICHLNYFTFSPIYDKSAQEWNLEIESTFDVVSSKPVGGQVIIAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVKTWWPHGHGIQTGYNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKITRFPIFLKGSNWIPADSFQDRVTSELLRLLLLSVVDANMNTLRVWGGGIYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKDYVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHLYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEKVSSTEDWSFNSKFSLHRQHHGGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEPVSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLMTEKTRTILFYPWEPTSKDELEQSFHVTSLTDIY 385 12.5 2 17 17 9 9 1.615 1.274 1.484 12 12 12 * * * 1.457666667 0.17201841 tr|A7LFP5|A7LFP5_HUMAN 100 5.00E-56 gi|194390136|dbj|BAG61830.1| unnamed protein product [Homo sapiens] 98.95 0 sp|O00462|MANBA_HUMAN Beta-mannosidase OS=Homo sapiens GN=MANBA PE=1 SV=3 100 0 A7LFP5 A7LFP5_HUMAN Beta-mannosidase OS=Homo sapiens GN=MANBA PE=2 SV=1 AGc2809 365 1.00E-100 COG3250 Beta-galactosidase/beta-glucuronidase G Carbohydrate transport and metabolism ; K01192|1|0.0|1758|hsa:4126|beta-mannosidase [EC:3.2.1.25] GO:0005975//carbohydrate metabolic process;GO:0006464//cellular protein modification process;GO:0006516//glycoprotein catabolic process GO:0043169//cation binding;GO:0004567//beta-mannosidase activity;GO:0005537//mannose binding GO:0005764//lysosome 4 sp|P35555|FBN1_HUMAN Fibrillin-1 OS=Homo sapiens GN=FBN1 PE=1 SV=3 366735 MRRGRLLEIALGFTVLLASYTSHGADANLEAGNVKETRASRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYECKINGYPKRGRKRRSTNETDASNIEDQSETEANVSLASWDVEKTAIFAFNISHVSNKVRILELLPALTTLTNHNRYLIESGNEDGFFKINQKEGISYLHFTKKKPVAGTYSLQISSTPLYKKKELNQLEDKYDKDYLSGELGDNLKMKIQVLLH 2546 17.1 - 125 116 35 34 0.859 0.645 0.685 86 86 87 * * * 0.729666667 0.113777561 sp|P35555|FBN1_HUMAN 100 0 gi|311033452|sp|P35555.3|FBN1_HUMAN RecName: Full=Fibrillin-1; Flags: Precursor 100 0 sp|P35555|FBN1_HUMAN Fibrillin-1 OS=Homo sapiens GN=FBN1 PE=1 SV=3 100 0 H0YND0 H0YND0_HUMAN Fibrillin-1 (Fragment) OS=Homo sapiens GN=FBN1 PE=4 SV=1 - - - - - - - K06825|1|0.0|5573|hsa:2200|fibrillin 1 GO:0035582//sequestering of BMP in extracellular matrix;GO:0007507//heart development;GO:0001501//skeletal system development;GO:0035583//sequestering of TGFbeta in extracellular matrix GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0001527//microfibril 5 tr|B4DNG0|B4DNG0_HUMAN Olfactomedin-like protein 3 OS=Homo sapiens GN=OLFML3 PE=2 SV=1 44167 MLPLLEVAEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEFDEKVTGGPGTKGKGRRNEKYDMVTDCGYTISQVRSMKILKRFGGPAGLWTKDPLGQTEKIYVLDGTQNDTAFVFPRLRDFTLAMAARKASRVRVPFPWVGTGQLVYGGFLYFARRPPGRPGGGGEMENTLQLIKFHLANRTVVDSSVFPAEGLIPPYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERAALPYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV 252 12.2 1 19 19 4 4 1.843 1.837 2.334 11 13 13 * * * 2.004666667 0.28522681 tr|B4DNG0|B4DNG0_HUMAN 100 0 gi|297664005|ref|XP_002810446.1| PREDICTED: olfactomedin-like 3 isoform 1 [Pongo abelii] 100 0 sp|Q9NRN5|OLFL3_HUMAN Olfactomedin-like protein 3 OS=Homo sapiens GN=OLFML3 PE=2 SV=1 100 0 H2N6B0 H2N6B0_PONAB Uncharacterized protein OS=Pongo abelii GN=OLFML3 PE=4 SV=1 - - - - - - - K04593|1|1e-28|127|dre:57987|latrophilin 2 GO:0007275//multicellular organismal development - GO:0005576//extracellular region 6 tr|B4DGM0|B4DGM0_HUMAN cDNA FLJ60089, highly similar to PMS1 protein homolog 2 OS=Homo sapiens PE=2 SV=1 108985 MERAESSRSKLKDYGVDLIEVSDNGCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVNEVYHMYNRHQYPFVVLNISVDSECVDINVTPDKRQILLQEEKLLLAVLKTSLIGMFDSDVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQSPSLRTGEEKKDVSISRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTSGAISDKGVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSVGFSIPDTGSHCSSEYAASSPGDRGSQEHVDSQEKAPKTDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRFKKEEILSSSDICQKLVITQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQSEGEQNYRKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVDQHATDEKYNFEMLQQHTVLQGQRLTAPQTLNLTAVNEAVLIENLEIFRKNGFDFVIDENAPVTERAKLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN 25 0.9 3 7 7 1 1 0.747 0.589 0.664 2 2 2 - - - 0.666666667 0.079033748 tr|B4DGM0|B4DGM0_HUMAN 100 7.00E-177 gi|17942778|pdb|1H7U|A Chain A, Hpms2-atpgs >gi|17942779|pdb|1H7U|B Chain B, Hpms2-atpgs 99.63 0 sp|P54278|PMS2_HUMAN Mismatch repair endonuclease PMS2 OS=Homo sapiens GN=PMS2 PE=1 SV=2 100 0 B4DGM0 B4DGM0_HUMAN cDNA FLJ60089, highly similar to PMS1 protein homolog 2 OS=Homo sapiens PE=2 SV=1 YNL082w 240 7.00E-63 COG0323 DNA mismatch repair enzyme (predicted ATPase) L Replication, recombination and repair ; K10858|1|0.0|1644|hsa:5395|DNA mismatch repair protein PMS2 GO:0007131//reciprocal meiotic recombination;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0042493//response to drug;GO:0006200//ATP catabolic process;GO:0006298//mismatch repair GO:0032138//single base insertion or deletion binding;GO:0032407//MutSalpha complex binding;GO:0003697//single-stranded DNA binding;GO:0004519//endonuclease activity;GO:0016887//ATPase activity;GO:0005524//ATP binding GO:0032389//MutLalpha complex 7 tr|A6NIR2|A6NIR2_HUMAN Chromosome 1 open reading frame 41, isoform CRA_b OS=Homo sapiens GN=HSPB11 PE=1 SV=1 15567 MRKIDLCLSSEGSEVILATSSDEKHPPENIIDGNPETFWTTTGMFPQEFIICFHKHVRIERLVIQSYFVQTLKIEKSTSKEPVDFEQWIEKDLVHTEGQLQNEEIVVSEYTL 72 10.7 2 2 2 1 1 0.849 --- 0.751 2 1 2 - - - 0.8 0.069296465 tr|A6NIR2|A6NIR2_HUMAN 100 2.00E-59 gi|119627123|gb|EAX06718.1| chromosome 1 open reading frame 41, isoform CRA_b [Homo sapiens] 99.07 6.00E-58 sp|Q9Y547|HSB11_HUMAN Heat shock protein beta-11 OS=Homo sapiens GN=HSPB11 PE=1 SV=1 100 2.00E-33 A6NG08 A6NG08_HUMAN Heat shock protein beta-11 OS=Homo sapiens GN=HSPB11 PE=4 SV=1 - - - - - - - - GO:0006950//response to stress;GO:0007155//cell adhesion - GO:0005929//cilium;GO:0030992//intraflagellar transport particle B 8 sp|Q16531|DDB1_HUMAN DNA damage-binding protein 1 OS=Homo sapiens GN=DDB1 PE=1 SV=1 144873 MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLEELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREKEFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPNRETDDTLVLSFVGQTRVLMLNGEEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQIHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGLWTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSHYLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSGMKREATADDLIKVVEELTRIH 268 12.4 - 21 21 12 12 0.801 0.936 0.791 11 11 11 - - - 0.842666667 0.080983537 sp|Q16531|DDB1_HUMAN 100 0 gi|361132523|pdb|4A0L|A Chain A, Structure Of Ddb1-Ddb2-Cul4b-Rbx1 Bound To A 12 Bp Abasic Site Containing Dna-Duplex >gi|361132525|pdb|4A0L|C Chain C, Structure Of Ddb1-Ddb2-Cul4b-Rbx1 Bound To A 12 Bp Abasic Site Containing Dna-Duplex 100 0 sp|Q16531|DDB1_HUMAN DNA damage-binding protein 1 OS=Homo sapiens GN=DDB1 PE=1 SV=1 100 1.00E-137 F5H775 F5H775_HUMAN DNA damage-binding protein 1 (Fragment) OS=Homo sapiens GN=DDB1 PE=4 SV=1 - - - - - - - K10610|1|0.0|2316|hsa:1642|DNA damage-binding protein 1 GO:0043161//proteasomal ubiquitin-dependent protein catabolic process;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0000075//cell cycle checkpoint;GO:0016055//Wnt receptor signaling pathway;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0019048//virus-host interaction GO:0003684//damaged DNA binding;GO:0005515//protein binding GO:0031464//Cul4A-RING ubiquitin ligase complex;GO:0031465//Cul4B-RING ubiquitin ligase complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm 9 tr|B3KTW2|B3KTW2_HUMAN cDNA FLJ38853 fis, clone MESAN2010321, highly similar to LIM domain and actin-binding protein 1 OS=Homo sapiens PE=2 SV=1 65286 MEQKENVPPGPEVCITHQEGEKISANENSLAVRSTPAEDDSRDSQVKSEVQQPVHPKPLSPDSRASSLSESSPPKAMKKFQAPARETCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFKSKGNYDEGFGHRPHKDLWASKNENEEILERPAQLANARETPHSPGVEDAPIAKVGVLAASMEAKASSQQEKEDKPAETKKLRIAWPPPTELGSSGSALEEGIKMSKPKWPPEDEISKPEVPEDVDLDLKKLRRPSSLKERSRPFTVAASFQSTSVKSPKTVSPPIRKGWSMSEQSEESVGGRVAERKQVENAKASKKNGNVGKTTWQNKESKGETGKRSKEGHSLEMENENLVENGADSDEDDNSFLKQQSPQEPKSLNWSSFVDNTFAEEFTTQNQKSQDVELWEGEVVKELSVEEQIKRNRYYDEDEDEE 72 11.4 5 3 3 3 3 --- 0.916 0.871 1 2 2 - - - 0.8935 0.031819805 tr|B3KTW2|B3KTW2_HUMAN 100 0 gi|193788330|dbj|BAG53224.1| unnamed protein product [Homo sapiens] 99.78 0 sp|Q9UHB6|LIMA1_HUMAN LIM domain and actin-binding protein 1 OS=Homo sapiens GN=LIMA1 PE=1 SV=1 100 5.00E-25 F8VRN8 F8VRN8_HUMAN LIM domain and actin-binding protein 1 OS=Homo sapiens GN=LIMA1 PE=4 SV=1 - - - - - - - K09377|1|9e-08|58.9|xla:373825|cysteine and glycine-rich protein GO:0051017//actin filament bundle assembly;GO:0030835//negative regulation of actin filament depolymerization;GO:0031529//ruffle organization GO:0003785//actin monomer binding;GO:0008270//zinc ion binding;GO:0051015//actin filament binding GO:0001725//stress fiber;GO:0005925//focal adhesion;GO:0005737//cytoplasm 10 sp|Q9UBI6|GBG12_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 OS=Homo sapiens GN=GNG12 PE=1 SV=3 10245 MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKTCIIL 110 25 1 4 4 2 2 0.772 0.663 0.597 2 3 3 - - - 0.677333333 0.08837609 sp|Q9UBI6|GBG12_HUMAN 100 9.00E-35 gi|51036603|ref|NP_061329.3| guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 precursor [Homo sapiens] >gi|197100455|ref|NP_001126086.1| guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 precursor [Pongo abelii] >gi|387849113|ref|NP_001248684.1| guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [Macaca mulatta] >gi|12229817|sp|Q9UBI6.3|GBG12_HUMAN RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; Flags: Precursor >gi|75061903|sp|Q5RBQ0.3|GBG12_PONAB RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; Flags: Precursor >gi|6164871|gb|AAF04571.1|AF188181_1 G-protein gamma 12 subunit [Homo sapiens] >gi|6563252|gb|AAF17220.1|AF119663_1 G-protein gamma-12 subunit [Homo sapiens] >gi|20147651|gb|AAM12593.1|AF493879_1 guanine nucleotide binding protein gamma 12 [Homo sapiens] >gi|33150734|gb|AAP97245.1|AF123766_1 G-protein gamma-12 subunit [Homo sapiens] >gi|14039774|gb|AAK53385.1| G protein gamma 12 subunit [Homo sapiens] >gi|119626889|gb|EAX06484.1| guanine nucleotide binding protein (G protein), gamma 12, isoform CRA_a [Homo sapiens] >gi|119626890|gb|EAX06485.1| guanine nucleotide binding protein (G protein), gamma 12, isoform CRA_a [Homo sapiens] >gi|119626891|gb|EAX06486.1| guanine nucleotide binding protein (G protein), gamma 12, isoform CRA_a [Homo sapiens] 100 1.00E-35 sp|Q9UBI6|GBG12_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 OS=Homo sapiens GN=GNG12 PE=1 SV=3 100 4.00E-34 G7NWY8 G7NWY8_MACFA Guanine nucleotide-binding protein subunit gamma OS=Macaca fascicularis GN=EGM_00739 PE=3 SV=1 - - - - - - - K04347|1|9e-36|148|ptr:100609242|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 GO:0021987//cerebral cortex development;GO:0007268//synaptic transmission;GO:0071377//cellular response to glucagon stimulus;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006112//energy reserve metabolic process;GO:0044281//small molecule metabolic process;GO:0032496//response to lipopolysaccharide GO:0004871//signal transducer activity;GO:0042301//phosphate ion binding GO:0005834//heterotrimeric G-protein complex;GO:0005884//actin filament 11 sp|P35052|GPC1_HUMAN Glypican-1 OS=Homo sapiens GN=GPC1 PE=1 SV=2 69113 MELRARGWWLLCAAAALVACARGDPASKSRSCGEVRQIYGAKGFSLSDVPQAEISGEHLRICPQGYTCCTSEMEENLANRSHAELETALRDSSRVLQAMLATQLRSFDDHFQHLLNDSERTLQATFPGAFGELYTQNARAFRDLYSELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLLPDDYLDCLGKQAEALRPFGEAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLGPECSRAVMKLVYCAHCLGVPGARPCPDYCRNVLKGCLANQADLDAEWRNLLDSMVLITDKFWGTSGVESVIGSVHTWLAEAINALQDNRDTLTAKVIQGCGNPKVNPQGPGPEEKRRRGKLAPRERPPSGTLEKLVSEAKAQLRDVQDFWISLPGTLCSEKMALSTASDDRCWNGMARGRYLPEVMGDGLANQINNPEVEVDITKPDMTIRQQIMQLKIMTNRLRSAYNGNDVDFQDASDDGSGSGSGDGCLDDLCSRKVSRKSSSSRTPLTHALPGLSEQEGQKTSAASCPQPPTFLLPLLLFLALTVARPRWR 743 23.7 - 40 40 10 10 1.389 1.001 1.127 28 30 30 * - * 1.172333333 0.197932648 sp|P35052|GPC1_HUMAN 100 0 gi|167001141|ref|NP_002072.2| glypican-1 precursor [Homo sapiens] >gi|292495012|sp|P35052.2|GPC1_HUMAN RecName: Full=Glypican-1; Contains: RecName: Full=Secreted glypican-1; Flags: Precursor 100 0 sp|P35052|GPC1_HUMAN Glypican-1 OS=Homo sapiens GN=GPC1 PE=1 SV=2 100 1.00E-124 B3KTD1 B3KTD1_HUMAN Glypican 1, isoform CRA_a OS=Homo sapiens GN=GPC1 PE=2 SV=1 - - - - - - - K08107|1|0.0|989|hsa:2817|glypican 1 GO:0007411//axon guidance;GO:2001016//positive regulation of skeletal muscle cell differentiation;GO:0032288//myelin assembly;GO:0006027//glycosaminoglycan catabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0030200//heparan sulfate proteoglycan catabolic process;GO:0005975//carbohydrate metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0014037//Schwann cell differentiation;GO:0044281//small molecule metabolic process;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway GO:0043236//laminin binding;GO:0043395//heparan sulfate proteoglycan binding;GO:0017134//fibroblast growth factor binding;GO:0070052//collagen V binding;GO:0005507//copper ion binding GO:0045121//membrane raft;GO:0005615//extracellular space;GO:0031225//anchored to membrane;GO:0005796//Golgi lumen;GO:0043025//neuronal cell body;GO:0005578//proteinaceous extracellular matrix;GO:0005768//endosome;GO:0043202//lysosomal lumen;GO:0005887//integral to plasma membrane 12 tr|A0A087WVM3|A0A087WVM3_HUMAN Protein CYR61 OS=Homo sapiens GN=CYR61 PE=4 SV=1 52439 MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRCEDAVPLRRWGDIFQERHDDPVKCNYNCPHANEAAFPFYRLFNDIHKFRD 125 3.7 4 2 2 1 1 0.748 0.397 0.383 2 2 2 - - - 0.509333333 0.206809897 tr|A0A087WVM3|A0A087WVM3_HUMAN 93.69 3.00E-167 gi|6649849|gb|AAF21597.1|AF003114_1 tumor RMS cell line RD specific product [Homo sapiens] 93.52 0 sp|O00622|CYR61_HUMAN Protein CYR61 OS=Homo sapiens GN=CYR61 PE=1 SV=1 100 0 F8W9U7 F8W9U7_HUMAN Protein CYR61 OS=Homo sapiens GN=CYR61 PE=4 SV=1 - - - - - - - K06829|1|0.0|649|hsa:3491|cysteine rich protein 61 GO:0043065//positive regulation of apoptotic process;GO:2000304//positive regulation of ceramide biosynthetic process;GO:0060710//chorio-allantoic fusion;GO:0045669//positive regulation of osteoblast differentiation;GO:0001558//regulation of cell growth;GO:0010518//positive regulation of phospholipase activity;GO:0030513//positive regulation of BMP signaling pathway;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0061036//positive regulation of cartilage development;GO:0072593//reactive oxygen species metabolic process;GO:0044319//wound healing, spreading of cells;GO:0010811//positive regulation of cell-substrate adhesion;GO:0003278//apoptotic process involved in heart morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006935//chemotaxis;GO:0003281//ventricular septum development;GO:0030198//extracellular matrix organization;GO:0030335//positive regulation of cell migration;GO:0060591//chondroblast differentiation;GO:0060716//labyrinthine layer blood vessel development;GO:0043066//negative regulation of apoptotic process;GO:0060413//atrial septum morphogenesis;GO:0002041//intussusceptive angiogenesis;GO:0045860//positive regulation of protein kinase activity;GO:0003181//atrioventricular valve morphogenesis;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0033690//positive regulation of osteoblast proliferation GO:0008201//heparin binding;GO:0005178//integrin binding;GO:0050840//extracellular matrix binding;GO:0005520//insulin-like growth factor binding GO:0005576//extracellular region 13 tr|B2RMS9|B2RMS9_HUMAN Inter-alpha (Globulin) inhibitor H4 (Plasma Kallikrein-sensitive glycoprotein) OS=Homo sapiens GN=ITIH4 PE=2 SV=1 116303 MKPPRPVRTCSKVLVLLSLLAIHQTTTAEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRANTVQEATFQMELPKKAFITNFSMNIDGMTYPGIIKEKAEAQAQYSAAVAKGKSAGLVKATGRNMEQFQVSVSVAPNAKITFELVYEELLKRRLGVYELLLKVRPQQLVKHLQMDIHIFEPQGISFLETESTFMTNQLVDALTTWQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNLIIRYDVDRAISGGSIQIENGYFVHYFAPEGLTTMPKNVVFVIDKSGSMSGRKIQQTREALIKILDDLSPRDQFNLIVFSTEATQWRPSLVPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTDGDPTVGETNPRSIQNNVREAVSGRYSLFCLGFGFDVSYAFLEKLALDNGGLARRIHEDSDSALQLQDFYQEVANPLLTAVTFEYPSNAVEEVTQNNFRLLFKGSEMVVAGKLQDRGPDVLTATVSGKLPTQNITFQTESSVAEQEAEFQSPKYIFHNFMERLWAYLTIQQLLEQTVSASDADQQALRNQALNLSLAYSFVTPLTSMVVTKPDDQEQSQVAEKPMEGESRNRNVHSGSTFFKYYLQGAKIPKPEASFSPRRGWNRQAGAAGSRMNFRPGVLSSRQLGLPGPPDVPDHAAYHPFRRLAILPASATPATSNPDPAVSRVMNMKIEETTMTTQTPAPIQAPSAILPLPGQSVERLCVDPRHRQGPVNLLSDPEQGVEVTGQYEREKAGFSWIEVTFKNPLVWVHASPEHVVVTRNRRSSAYKWKETLFSVMPGLKMTMDKTGLLLLSDPDKVTIGLLFWDGRGEGLRLLLRDTDRFSSHVGGTLGQFYQEVLWGSPAASDDGRRTLRVQGNDHSATRERRLDYQEGPPGVEISCWSVEL 231 11.2 1 12 12 8 8 0.607 2.234 1.86 6 6 3 - * * 1.567 0.852155502 tr|B2RMS9|B2RMS9_HUMAN 100 0 gi|187950343|gb|AAI36394.1| Inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein) [Homo sapiens] 99.78 0 sp|Q14624|ITIH4_HUMAN Inter-alpha-trypsin inhibitor heavy chain H4 OS=Homo sapiens GN=ITIH4 PE=1 SV=4 100 0 F5GXQ1 F5GXQ1_HUMAN 35 kDa inter-alpha-trypsin inhibitor heavy chain H4 OS=Homo sapiens GN=ITIH4 PE=4 SV=1 alr4412 111 8.00E-24 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R General function prediction only ; K05316|1|8e-09|63.5|cqu:CpipJ_CPIJ005979|voltage-dependent calcium channel alpha-2/delta, invertebrate!K04860|4|1e-07|59.3|dre:100535196|voltage-dependent calcium channel alpha-2/delta-3 GO:0010951//negative regulation of endopeptidase activity;GO:0030212//hyaluronan metabolic process;GO:0006953//acute-phase response GO:0004867//serine-type endopeptidase inhibitor activity GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005576//extracellular region 14 tr|B2R548|B2R548_HUMAN Prefoldin subunit 4 OS=Homo sapiens PE=2 SV=1 19361 MAATMKKAAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEETDALESRVESIQRVLADLKVQLYAKFGSNINLEADES 152 11.2 2 3 3 1 1 0.794 0.859 0.755 3 3 3 - - - 0.802666667 0.052538874 tr|B2R548|B2R548_HUMAN 100 5.00E-53 gi|189065272|dbj|BAG34995.1| unnamed protein product [Homo sapiens] 99.19 2.00E-53 sp|Q9NQP4|PFD4_HUMAN Prefoldin subunit 4 OS=Homo sapiens GN=PFDN4 PE=1 SV=1 100 2.00E-52 B2R548 B2R548_HUMAN cDNA, FLJ92340, highly similar to Homo sapiens prefoldin 4 (PFDN4), mRNA OS=Homo sapiens PE=2 SV=1 YNL153c 72.8 1.00E-13 COG1382 Prefoldin, chaperonin cofactor O Posttranslational modification, protein turnover, chaperones ; K09550|1|5e-54|209|ecb:100053649|prefoldin subunit 4 GO:0051086//chaperone mediated protein folding independent of cofactor GO:0051087//chaperone binding;GO:0051082//unfolded protein binding GO:0016272//prefoldin complex;GO:0005634//nucleus;GO:0005739//mitochondrion 15 tr|A8K651|A8K651_HUMAN cDNA FLJ75700, highly similar to Homo sapiens complement component 1, q subcomponent binding protein (C1QBP), nuclear gene encoding mitochondrial protein, mRNA OS=Homo sapiens PE=2 SV=1 36627 MLPLLRCVPRVLGSSVAGLRAAAPASPFRQLLQPAPRLCTRPFGLLSVRAGSERRPGLLRPRGPCACGCGCGSLHTDGDKAFVDFLSDEIKEERKIQKHKTLPKMSGGWELELNGTEAKLVRKVAGEKITVTFNINNSISPTFDGEEEPSQGQKVEEQEPELTSTPNFVVEVIKNDDGKRALVLDCHYPEDEVGQEDEAESDIFSIREVSFQSTGESEWKDTNYTLNTDSLDWALYDHLMDFLADRGVDNTFADELVELSTALEHQEYITFLEDLKSFVKSQ 105 9.6 1 5 5 2 2 0.773 0.623 0.658 4 4 3 - - - 0.684666667 0.078475049 tr|A8K651|A8K651_HUMAN 100 1.00E-149 gi|158256464|dbj|BAF84205.1| unnamed protein product [Homo sapiens] 99.29 2.00E-149 sp|Q07021|C1QBP_HUMAN Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens GN=C1QBP PE=1 SV=1 100 5.00E-149 A8K651 A8K651_HUMAN cDNA FLJ75700, highly similar to Homo sapiens complement component 1, q subcomponent binding protein (C1QBP), nuclear gene encoding mitochondrial protein, mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K15414|1|2e-149|528|hsa:708|complement component 1 Q subcomponent-binding protein, mitochondrial GO:0007597//blood coagulation, intrinsic pathway;GO:0019048//virus-host interaction;GO:0006955//immune response GO:0001849//complement component C1q binding;GO:0005080//protein kinase C binding GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005759//mitochondrial matrix;GO:0005634//nucleus 16 tr|A2VDJ4|A2VDJ4_HUMAN GNPTG protein (Fragment) OS=Homo sapiens GN=GNPTG PE=2 SV=1 38319 CRACRAASAGAAKMKVVEEPNAFGVNNPFLPQASRLQAKRDPSPVSGPVHLFRLSGKCFSLVESTYKYEFCPFHNVTQHEQTFRWNAYSGILGIWHEWEIANNTFTGMWMRDGDACRSRSRQSKVELACGKSNRLAHVSEPSTCVYALTFETPLVCHPHALLVYPTLPEALQRQWDQVEQDLADELITPQGHEKLLRTLFEDAGYLKTPEENEPTQLEGGPDSLGFETLENCRKAHKELSKEIKRLKGLLTQHGIPYTRPTETSNLEHLGHETPRAKSPEQLRGDPGDLFYV 157 14 2 7 7 3 3 1.339 1.165 1.21 5 5 4 - - - 1.238 0.090316112 tr|A2VDJ4|A2VDJ4_HUMAN 100 8.00E-162 gi|37782420|gb|AAP34456.1| LP2537 [Homo sapiens] 100 9.00E-164 sp|Q9UJJ9|GNPTG_HUMAN N-acetylglucosamine-1-phosphotransferase subunit gamma OS=Homo sapiens GN=GNPTG PE=1 SV=1 100 3.00E-165 A2VDJ4 A2VDJ4_HUMAN GNPTG protein (Fragment) OS=Homo sapiens GN=GNPTG PE=2 SV=1 - - - - - - - K10087|1|1e-163|575|hsa:84572|N-acetylglucosamine-1-phosphate transferase, gamma subunit GO:0016256//N-glycan processing to lysosome GO:0003976//UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity GO:0000139//Golgi membrane;GO:0005576//extracellular region 17 sp|P07339|CATD_HUMAN Cathepsin D OS=Homo sapiens GN=CTSD PE=1 SV=1 >tr|V9HWI3|V9HWI3_HUMAN Cathepsin D (Lysosomal aspartyl peptidase), isoform CRA_a OS=Homo sapiens GN=HEL-S-130P PE=2 SV=1 52338 MQPSSLLPLALCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEAARL 2175 40.3 - 109 58 12 8 1.034 0.748 0.984 36 37 37 - * - 0.922 0.152748159 sp|P07339|CATD_HUMAN 100 0 gi|4503143|ref|NP_001900.1| cathepsin D preproprotein [Homo sapiens] >gi|115717|sp|P07339.1|CATD_HUMAN RecName: Full=Cathepsin D; Contains: RecName: Full=Cathepsin D light chain; Contains: RecName: Full=Cathepsin D heavy chain; Flags: Precursor >gi|29678|emb|CAA28955.1| cathepsin D [Homo sapiens] >gi|179948|gb|AAA51922.1| cathepsin D [Homo sapiens] >gi|181180|gb|AAB59529.1| preprocathepsin D [Homo sapiens] >gi|16740920|gb|AAH16320.1| Cathepsin D [Homo sapiens] >gi|30582659|gb|AAP35556.1| cathepsin D (lysosomal aspartyl protease) [Homo sapiens] >gi|48146011|emb|CAG33228.1| CTSD [Homo sapiens] >gi|54697170|gb|AAV38957.1| cathepsin D (lysosomal aspartyl protease) [Homo sapiens] >gi|119622866|gb|EAX02461.1| cathepsin D (lysosomal aspartyl peptidase), isoform CRA_a [Homo sapiens] >gi|119622867|gb|EAX02462.1| cathepsin D (lysosomal aspartyl peptidase), isoform CRA_a [Homo sapiens] >gi|119622868|gb|EAX02463.1| cathepsin D (lysosomal aspartyl peptidase), isoform CRA_a [Homo sapiens] 100 0 sp|P07339|CATD_HUMAN Cathepsin D OS=Homo sapiens GN=CTSD PE=1 SV=1 100 5.00E-163 C9JH19 C9JH19_HUMAN Cathepsin D (Fragment) OS=Homo sapiens GN=CTSD PE=3 SV=1 - - - - - - - K01379|1|0.0|781|hsa:1509|cathepsin D [EC:3.4.23.5] GO:0008219//cell death;GO:0000045//autophagic vacuole assembly;GO:0006508//proteolysis;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0004190//aspartic-type endopeptidase activity GO:0005739//mitochondrion;GO:0043202//lysosomal lumen;GO:0005615//extracellular space;GO:0042470//melanosome;GO:0031012//extracellular matrix 18 sp|P14324|FPPS_HUMAN Farnesyl pyrophosphate synthase OS=Homo sapiens GN=FDPS PE=1 SV=4 55755 MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK 126 5.5 1 6 6 3 3 1.204 1.468 1.102 5 5 5 - - - 1.258 0.188880915 sp|P14324|FPPS_HUMAN 100 0 gi|40788949|dbj|BAA03523.2| KIAA1293 [Homo sapiens] 100 0 sp|P14324|FPPS_HUMAN Farnesyl pyrophosphate synthase OS=Homo sapiens GN=FDPS PE=1 SV=4 100 0 G3QDS5 G3QDS5_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=RUSC1 PE=3 SV=1 SPAC6F12.13c 321 2.00E-87 COG0142 Geranylgeranyl pyrophosphate synthase H Coenzyme transport and metabolism ; K00787|1|0.0|868|hsa:2224|farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] GO:0033384//geranyl diphosphate biosynthetic process;GO:0045337//farnesyl diphosphate biosynthetic process;GO:0019048//virus-host interaction;GO:0006695//cholesterol biosynthetic process GO:0004337//geranyltranstransferase activity;GO:0046872//metal ion binding;GO:0004161//dimethylallyltranstransferase activity GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005730//nucleolus 19 tr|Q6IB71|Q6IB71_HUMAN Proteasome subunit alpha type OS=Homo sapiens GN=PSMA3 PE=2 SV=1 34405 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKEEDESDDDNI 121 12.9 1 6 6 3 3 0.659 0.516 0.524 2 2 2 - - - 0.566333333 0.080351312 tr|Q6IB71|Q6IB71_HUMAN 100 1.00E-57 gi|148704617|gb|EDL36564.1| proteasome (prosome, macropain) subunit, alpha type 3, isoform CRA_b [Mus musculus] 100 3.00E-140 sp|P25788|PSA3_HUMAN Proteasome subunit alpha type-3 OS=Homo sapiens GN=PSMA3 PE=1 SV=2 100 7.00E-139 H2Q8D7 H2Q8D7_PANTR Proteasome subunit alpha type OS=Pan troglodytes GN=ENSG00000100567 PE=3 SV=1 PAB0417 150 1.00E-36 COG0638 20S proteasome, alpha and beta subunits O Posttranslational modification, protein turnover, chaperones ; K02727|1|3e-140|497|hsa:5684|20S proteasome subunit alpha 7 [EC:3.4.25.1] GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0019048//virus-host interaction;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0005515//protein binding;GO:0004298//threonine-type endopeptidase activity GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0019773//proteasome core complex, alpha-subunit complex 20 tr|I3L3N5|I3L3N5_HUMAN Platelet-activating factor acetylhydrolase IB subunit alpha (Fragment) OS=Homo sapiens GN=PAFAH1B1 PE=1 SV=1 28391 SADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSEVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 100 11.5 3 3 3 2 2 0.495 0.563 0.543 2 2 2 - * - 0.533666667 0.03494758 tr|I3L3N5|I3L3N5_HUMAN 100 1.00E-118 gi|194375910|dbj|BAG57299.1| unnamed protein product [Homo sapiens] 85.95 7.00E-118 sp|Q5REG7|LIS1_PONAB Platelet-activating factor acetylhydrolase IB subunit alpha OS=Pongo abelii GN=PAFAH1B1 PE=2 SV=3 100 4.00E-118 B4DF38 B4DF38_HUMAN Platelet-activating factor acetylhydrolase IB subunit alpha OS=Homo sapiens GN=PAFAH1B1 PE=2 SV=1 all0438_2 132 4.00E-31 COG2319 FOG: WD40 repeat R General function prediction only ; K01062|1|5e-118|423|bta:282513|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] GO:0021766//hippocampus development;GO:0046329//negative regulation of JNK cascade;GO:0008090//retrograde axon cargo transport;GO:0000236//mitotic prometaphase;GO:0050885//neuromuscular process controlling balance;GO:0000132//establishment of mitotic spindle orientation;GO:0016042//lipid catabolic process;GO:0007268//synaptic transmission;GO:0007405//neuroblast proliferation;GO:0010977//negative regulation of neuron projection development;GO:0001667//ameboidal cell migration;GO:0051081//nuclear envelope disassembly;GO:0007611//learning or memory;GO:0021540//corpus callosum morphogenesis;GO:0021819//layer formation in cerebral cortex;GO:0008344//adult locomotory behavior;GO:0001675//acrosome assembly;GO:0046469//platelet activating factor metabolic process;GO:0045931//positive regulation of mitotic cell cycle;GO:0047496//vesicle transport along microtubule;GO:0021895//cerebral cortex neuron differentiation;GO:0036035//osteoclast development;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0007097//nuclear migration;GO:0030036//actin cytoskeleton organization;GO:0000086//G2/M transition of mitotic cell cycle;GO:0048854//brain morphogenesis;GO:0051660//establishment of centrosome localization;GO:0017145//stem cell division;GO:0031023//microtubule organizing center organization;GO:0032319//regulation of Rho GTPase activity;GO:0009306//protein secretion;GO:0001764//neuron migration;GO:0045773//positive regulation of axon extension GO:0042803//protein homodimerization activity;GO:0008201//heparin binding;GO:0047179//platelet-activating factor acetyltransferase activity;GO:0034452//dynactin binding;GO:0045505//dynein intermediate chain binding;GO:0032403//protein complex binding;GO:0016787//hydrolase activity;GO:0043274//phospholipase binding;GO:0051219//phosphoprotein binding;GO:0008017//microtubule binding GO:0000235//astral microtubule;GO:0031512//motile primary cilium;GO:0033267//axon part;GO:0031982//vesicle;GO:0030426//growth cone;GO:0031252//cell leading edge;GO:0005829//cytosol;GO:0000776//kinetochore;GO:0031513//nonmotile primary cilium;GO:0048471//perinuclear region of cytoplasm;GO:0005871//kinesin complex;GO:0031965//nuclear membrane;GO:0005813//centrosome;GO:0005730//nucleolus;GO:0043025//neuronal cell body;GO:0005938//cell cortex 21 tr|A0A024R0A1|A0A024R0A1_HUMAN Colony stimulating factor 1 (Macrophage), isoform CRA_a OS=Homo sapiens GN=CSF1 PE=4 SV=1 66242 MTAPGAAGRCPPTTWLGSLLLLVCLLASRSITEEVSEYCSHMIGSGHLQSLQRLIDSQMETSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLKSCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSSQDVVTKPDCNCLYPKAIPSSDPASVSPHQPLAPSMAPVAGLTWEDSEGTEGSSLLPGEQPLHTVDPGSAKQRPPRSTCQSFEPPETPVVKDSTIGGSPQPRPSVGAFNPGMEDILDSAMGTNWVPEEASGEASEIPVPQGTELSPSRPGGGSMQTEPARPSNFLSASSPLPASAKGQQPADVTGTALPRVGPVRPTGQDWNHTPQKTDHPSALLRDPPEPGSPRISSLRPQGLSNPSTLSAQPQLSRSHSSGSVLPLGELEGRRSTRDRRSPAEPEGGPASEGAARPLPRFNSVPLTDTGHERQSEGSSSPQLQESVFHLLVPSVILVLLAVGGLLFYRWRRRSHQEPQRADSPLEQPEGSPLTQDDRQVELPV 174 7 4 11 11 3 3 1.617 0.825 1.325 5 6 5 * - - 1.255666667 0.40052632 tr|A0A024R0A1|A0A024R0A1_HUMAN 100 3.00E-82 gi|402550470|pdb|4FA8|E Chain E, Multi-Pronged Modulation Of Cytokine Signaling >gi|402550471|pdb|4FA8|F Chain F, Multi-Pronged Modulation Of Cytokine Signaling >gi|402550472|pdb|4FA8|G Chain G, Multi-Pronged Modulation Of Cytokine Signaling 99.82 0 sp|P09603|CSF1_HUMAN Macrophage colony-stimulating factor 1 OS=Homo sapiens GN=CSF1 PE=1 SV=2 100 3.00E-56 H7BY18 H7BY18_HUMAN Macrophage colony-stimulating factor 1 (Fragment) OS=Homo sapiens GN=CSF1 PE=4 SV=1 - - - - - - - K05453|1|0.0|1053|hsa:1435|macrophage colony-stimulating factor 1 GO:0042117//monocyte activation;GO:0010628//positive regulation of gene expression;GO:0030278//regulation of ossification;GO:0048873//homeostasis of number of cells within a tissue;GO:0003006//developmental process involved in reproduction;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0040018//positive regulation of multicellular organism growth;GO:0045657//positive regulation of monocyte differentiation;GO:0060763//mammary duct terminal end bud growth;GO:0060611//mammary gland fat development;GO:0001954//positive regulation of cell-matrix adhesion;GO:0045860//positive regulation of protein kinase activity;GO:0046579//positive regulation of Ras protein signal transduction;GO:0006954//inflammatory response;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0042488//positive regulation of odontogenesis of dentin-containing tooth;GO:0045651//positive regulation of macrophage differentiation;GO:0045672//positive regulation of osteoclast differentiation;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0030335//positive regulation of cell migration;GO:0045087//innate immune response GO:0005157//macrophage colony-stimulating factor receptor binding;GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0042803//protein homodimerization activity GO:0005615//extracellular space;GO:0016021//integral to membrane;GO:0043235//receptor complex;GO:0048471//perinuclear region of cytoplasm;GO:0005886//plasma membrane 22 tr|Q6DEN2|Q6DEN2_HUMAN DPYSL3 protein OS=Homo sapiens GN=DPYSL3 PE=2 SV=1 86488 MASGRRGWDSSHEDDLPVYLARPGTTDQVPRQKYGGMFCNVEGAFESKTLDFDALSVGQRGAKTPRSGQGSDRGSGSRPGIEGDTPRRGQGREESREPAPASPAPAGVEIRSATGKEVLQNLGPKDKSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLKMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKGGTPAGSARGSPTRPNPPVRNLHQSGFSLSGTQVDEGVRSASKRIVAPPGGRSNITSLS 155 7.5 - 7 6 4 3 1.052 1.057 1.123 5 5 5 - - - 1.077333333 0.039627432 tr|Q6DEN2|Q6DEN2_HUMAN 100 0 gi|50417352|gb|AAH77077.1| DPYSL3 protein [Homo sapiens] 99.29 0 sp|Q14195|DPYL3_HUMAN Dihydropyrimidinase-related protein 3 OS=Homo sapiens GN=DPYSL3 PE=1 SV=1 100 0 Q6DEN2 Q6DEN2_HUMAN DPYSL3 protein OS=Homo sapiens GN=DPYSL3 PE=2 SV=1 PA0441 436 9.00E-122 COG0044 Dihydroorotase and related cyclic amidohydrolases F Nucleotide transport and metabolism ; K07528|1|0.0|959|gga:395155|dihydropyrimidinase-like 2 GO:0007411//axon guidance;GO:0030336//negative regulation of cell migration;GO:0051017//actin filament bundle assembly;GO:0006208//pyrimidine nucleobase catabolic process;GO:0051764//actin crosslink formation;GO:0048678//response to axon injury;GO:0071345//cellular response to cytokine stimulus;GO:0010976//positive regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0051260//protein homooligomerization;GO:0051491//positive regulation of filopodium assembly GO:0035374//chondroitin sulfate binding;GO:0051219//phosphoprotein binding;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0017124//SH3 domain binding GO:0070382//exocytic vesicle;GO:0030027//lamellipodium;GO:0030426//growth cone;GO:0031941//filamentous actin;GO:0044297//cell body;GO:0005615//extracellular space;GO:0005829//cytosol 23 tr|A0A024R172|A0A024R172_HUMAN Leukotriene B4 12-hydroxydehydrogenase, isoform CRA_a OS=Homo sapiens GN=LTB4DH PE=4 SV=1 45825 MVRTKTWTLKKHFVGYPTNSDFELKTSELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEGDTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKEYIIEGFENMPAAFMGMLKGDNLGKTIVKA 94 5.8 2 3 3 1 1 0.983 --- --- 2 1 1 - - - 0.983 - tr|A0A024R172|A0A024R172_HUMAN 100 5.00E-173 gi|23271371|gb|AAH35228.1| Prostaglandin reductase 1 [Homo sapiens] >gi|119579478|gb|EAW59074.1| leukotriene B4 12-hydroxydehydrogenase, isoform CRA_a [Homo sapiens] >gi|119579479|gb|EAW59075.1| leukotriene B4 12-hydroxydehydrogenase, isoform CRA_a [Homo sapiens] 99.7 2.00E-173 sp|Q14914|PTGR1_HUMAN Prostaglandin reductase 1 OS=Homo sapiens GN=PTGR1 PE=1 SV=2 100 3.00E-75 Q5JVP3 Q5JVP3_HUMAN Leukotriene B4 12-hydroxydehydrogenase, isoform CRA_d OS=Homo sapiens GN=PTGR1 PE=2 SV=1 BS_yfmJ 249 4.00E-66 COG2130 Putative NADP-dependent oxidoreductases R General function prediction only ; K13948|1|2e-173|608|hsa:22949|rostaglandin reductase 1 [EC:1.3.1.74 1.3.1.48] GO:0009636//response to toxic substance;GO:0006691//leukotriene metabolic process;GO:0055114//oxidation-reduction process GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0032440//2-alkenal reductase [NAD(P)] activity;GO:0008270//zinc ion binding;GO:0047522//15-oxoprostaglandin 13-oxidase activity;GO:0000166//nucleotide binding;GO:0036132//13-prostaglandin reductase activity GO:0005737//cytoplasm 24 tr|J3QS39|J3QS39_HUMAN Ubiquitin (Fragment) OS=Homo sapiens GN=UBB PE=4 SV=1 13505 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEV 420 36.6 30 22 22 3 3 0.769 0.603 0.7 8 9 9 * * * 0.690666667 0.083392646 tr|J3QS39|J3QS39_HUMAN 100 1.00E-36 gi|24640086|ref|NP_727078.1| Ubiquitin-5E [Drosophila melanogaster] >gi|194896187|ref|XP_001978429.1| GG17684 [Drosophila erecta] >gi|22831806|gb|AAF46142.3| Ubiquitin-5E [Drosophila melanogaster] >gi|190650078|gb|EDV47356.1| GG17684 [Drosophila erecta] >gi|208879484|gb|ACI31287.1| GH17761p [Drosophila melanogaster] 100 7.00E-47 sp|P0CG50|UBC_MOUSE Polyubiquitin-C OS=Mus musculus GN=Ubc PE=1 SV=2 100 3.00E-45 Q5CKW6 Q5CKW6_CRYHO Ubiquitin B OS=Cryptosporidium hominis GN=Chro.50123 PE=4 SV=1 YLL039c 180 5.00E-46 COG5272 Ubiquitin O Posttranslational modification, protein turnover, chaperones ; K08770|1|5e-47|186|dya:Dyak_GE18016|ubiquitin C - - 25 tr|Q2TU84|Q2TU84_HUMAN Aspartate aminotransferase OS=Homo sapiens GN=GIG18 PE=2 SV=1 53211 MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLPILGLAEFRSCASRLALEDDSPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTKIQ 122 14 1 7 7 4 4 1.04 0.907 1.115 6 5 6 - - - 1.020666667 0.105339135 tr|Q2TU84|Q2TU84_HUMAN 100 0 gi|46981967|gb|AAT08032.1| growth-inhibiting protein 18 [Homo sapiens] 99.76 0 sp|P17174|AATC_HUMAN Aspartate aminotransferase, cytoplasmic OS=Homo sapiens GN=GOT1 PE=1 SV=3 100 0 Q2TU84 Q2TU84_HUMAN Aspartate aminotransferase OS=Homo sapiens GN=GIG18 PE=2 SV=1 SPAC10F6.13c 390 2.00E-108 COG1448 Aspartate/tyrosine/aromatic aminotransferase E Amino acid transport and metabolism ; K14454|1|0.0|858|hsa:2805|aspartate aminotransferase, cytoplasmic [EC:2.6.1.1] GO:0019509//L-methionine salvage from methylthioadenosine;GO:0006114//glycerol biosynthetic process;GO:0006107//oxaloacetate metabolic process;GO:0006533//aspartate catabolic process;GO:0019551//glutamate catabolic process to 2-oxoglutarate;GO:0006532//aspartate biosynthetic process;GO:0032869//cellular response to insulin stimulus;GO:0055089//fatty acid homeostasis;GO:0019550//glutamate catabolic process to aspartate;GO:0051384//response to glucocorticoid stimulus;GO:0006595//polyamine metabolic process;GO:0006094//gluconeogenesis GO:0004609//phosphatidylserine decarboxylase activity;GO:0004069//L-aspartate:2-oxoglutarate aminotransferase activity;GO:0080130//L-phenylalanine:2-oxoglutarate aminotransferase activity;GO:0031406//carboxylic acid binding;GO:0030170//pyridoxal phosphate binding GO:0005829//cytosol;GO:0005764//lysosome;GO:0043679//axon terminus 26 tr|F6RFD5|F6RFD5_HUMAN Destrin OS=Homo sapiens GN=DSTN PE=1 SV=1 22117 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASSKDAIKKKFQGKCTHS 163 20.7 1 13 13 4 4 0.522 0.522 0.388 6 6 6 * * * 0.477333333 0.077364936 tr|F6RFD5|F6RFD5_HUMAN 100 7.00E-59 gi|58530848|ref|NP_001011546.1| destrin isoform b [Homo sapiens] >gi|119630679|gb|EAX10274.1| destrin (actin depolymerizing factor), isoform CRA_a [Homo sapiens] >gi|119630681|gb|EAX10276.1| destrin (actin depolymerizing factor), isoform CRA_a [Homo sapiens] >gi|444729534|gb|ELW69947.1| Destrin [Tupaia chinensis] 100 2.00E-70 sp|P60982|DEST_PIG Destrin OS=Sus scrofa GN=DSTN PE=1 SV=3 100 3.00E-68 H0V5S5 H0V5S5_CAVPO Uncharacterized protein (Fragment) OS=Cavia porcellus GN=DSTN PE=4 SV=1 - - - - - - - K10363|1|4e-71|265|ptr:458108|destrin (actin-depolymerizing factor) GO:0030836//positive regulation of actin filament depolymerization;GO:0000910//cytokinesis;GO:0051014//actin filament severing;GO:0006928//cellular component movement GO:0003779//actin binding GO:0030864//cortical actin cytoskeleton 27 sp|P15121|ALDR_HUMAN Aldose reductase OS=Homo sapiens GN=AKR1B1 PE=1 SV=3 >tr|A0A024R7A8|A0A024R7A8_HUMAN Aldo-keto reductase family 1, member B1 (Aldose reductase), isoform CRA_a OS=Homo sapiens GN=AKR1B1 PE=4 SV=1 44139 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFHEEF 56 20.3 - 8 8 6 6 0.779 1.035 0.914 2 2 2 - - - 0.909333333 0.128063786 sp|P15121|ALDR_HUMAN 100 3.00E-177 gi|218766520|pdb|2R24|A Chain A, Human Aldose Reductase Structure 100 2.00E-179 sp|P15121|ALDR_HUMAN Aldose reductase OS=Homo sapiens GN=AKR1B1 PE=1 SV=3 99.37 9.00E-177 G3R7U6 G3R7U6_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=AKR1B1 PE=4 SV=1 slr0942 241 1.00E-63 COG0656 Aldo/keto reductases, related to diketogulonate reductase R General function prediction only ; K00011|1|2e-179|628|hsa:231|aldehyde reductase [EC:1.1.1.21] GO:0044597//daunorubicin metabolic process;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0006950//response to stress;GO:0006700//C21-steroid hormone biosynthetic process;GO:0044598//doxorubicin metabolic process GO:0043795//glyceraldehyde oxidoreductase activity;GO:0009055//electron carrier activity;GO:0004032//alditol:NADP+ 1-oxidoreductase activity GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0005829//cytosol 28 tr|B3KQF4|B3KQF4_HUMAN cDNA FLJ90373 fis, clone NT2RP2004606, highly similar to Metalloproteinase inhibitor 1 OS=Homo sapiens PE=2 SV=1 26588 MAPFEPLASGILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQPRHLACLPREPGLCTWQSLRSQIA 2775 54.1 2 123 123 7 7 1.026 1.255 1.082 79 83 81 - - * 1.121 0.119377552 tr|B3KQF4|B3KQF4_HUMAN 100 3.00E-70 gi|34811011|pdb|1OO9|B Chain B, Orientation In Solution Of Mmp-3 Catalytic Domain And N- Timp-1 From Residual Dipolar Couplings >gi|118138585|pdb|2J0T|D Chain D, Crystal Structure Of The Catalytic Domain Of Mmp-1 In Complex With The Inhibitory Domain Of Timp-1 >gi|118138586|pdb|2J0T|E Chain E, Crystal Structure Of The Catalytic Domain Of Mmp-1 In Complex With The Inhibitory Domain Of Timp-1 >gi|118138587|pdb|2J0T|F Chain F, Crystal Structure Of The Catalytic Domain Of Mmp-1 In Complex With The Inhibitory Domain Of Timp-1 >gi|159162187|pdb|1D2B|A Chain A, The Mmp-Inhibitory, N-Terminal Domain Of Human Tissue Inhibitor Of Metalloproteinases-1 (N-Timp-1), Solution Nmr, 29 Structures 99.52 5.00E-109 sp|Q5RC60|TIMP1_PONAB Metalloproteinase inhibitor 1 OS=Pongo abelii GN=TIMP1 PE=2 SV=1 100 1.00E-31 Q5H9B4 Q5H9B4_HUMAN Metalloproteinase inhibitor 1 (Fragment) OS=Homo sapiens GN=TIMP1 PE=2 SV=1 - - - - - - - - GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:1901164//negative regulation of trophoblast cell migration;GO:0043086//negative regulation of catalytic activity;GO:0030168//platelet activation;GO:0022617//extracellular matrix disassembly;GO:0043066//negative regulation of apoptotic process;GO:0043249//erythrocyte maturation;GO:0007568//aging;GO:0034097//response to cytokine stimulus;GO:0043434//response to peptide hormone stimulus;GO:0008284//positive regulation of cell proliferation;GO:0002576//platelet degranulation GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0008191//metalloendopeptidase inhibitor activity GO:0005604//basement membrane;GO:0031093//platelet alpha granule lumen 29 sp|P07585|PGS2_HUMAN Decorin OS=Homo sapiens GN=DCN PE=1 SV=1 >tr|Q6FH10|Q6FH10_HUMAN DCN protein OS=Homo sapiens GN=DCN PE=2 SV=1 48582 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 1276 23.7 - 92 92 8 8 3.718 4.265 5.825 56 57 56 * * * 4.602666667 1.093332673 sp|P07585|PGS2_HUMAN 100 9.00E-68 gi|119617864|gb|EAW97458.1| decorin, isoform CRA_g [Homo sapiens] 100 0 sp|P07585|PGS2_HUMAN Decorin OS=Homo sapiens GN=DCN PE=1 SV=1 100 4.00E-35 F8VU58 F8VU58_HUMAN Decorin OS=Homo sapiens GN=DCN PE=4 SV=1 SPy1798 77.4 3.00E-14 COG4886 Leucine-rich repeat (LRR) protein S Function unknown ; K04660|1|0.0|677|ptr:452120|decorin GO:0042060//wound healing;GO:0030207//chondroitin sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0001890//placenta development;GO:0009887//organ morphogenesis;GO:0007519//skeletal muscle tissue development;GO:0007568//aging;GO:0030208//dermatan sulfate biosynthetic process;GO:0001822//kidney development;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0044281//small molecule metabolic process;GO:0032496//response to lipopolysaccharide;GO:0009612//response to mechanical stimulus GO:0047485//protein N-terminus binding;GO:0050840//extracellular matrix binding;GO:0005518//collagen binding;GO:0005539//glycosaminoglycan binding GO:0005796//Golgi lumen;GO:0043202//lysosomal lumen;GO:0005615//extracellular space;GO:0005589//collagen type VI 30 sp|Q08629|TICN1_HUMAN Testican-1 OS=Homo sapiens GN=SPOCK1 PE=1 SV=1 62078 MPAIAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDKYWNRFRDDDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFDTSILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRAVTEDDEDEDDDKEDEVGYIW 178 12.8 - 13 13 5 5 0.744 0.593 0.556 10 10 10 * * * 0.631 0.099594177 sp|Q08629|TICN1_HUMAN 100 0 gi|4759164|ref|NP_004589.1| testican-1 precursor [Homo sapiens] >gi|24212472|sp|Q08629.1|TICN1_HUMAN RecName: Full=Testican-1; AltName: Full=Protein SPOCK; Flags: Precursor >gi|7248845|gb|AAF43687.1|AF231124_1 testican-1 [Homo sapiens] >gi|793845|emb|CAA51999.1| testican [Homo sapiens] 100 0 sp|Q08629|TICN1_HUMAN Testican-1 OS=Homo sapiens GN=SPOCK1 PE=1 SV=1 100 8.00E-70 D6RB21 D6RB21_HUMAN Testican-1 (Fragment) OS=Homo sapiens GN=SPOCK1 PE=4 SV=1 - - - - - - - K08136|1|0.0|828|hsa:6695|sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) GO:0001764//neuron migration;GO:0010812//negative regulation of cell-substrate adhesion;GO:0001558//regulation of cell growth;GO:0010951//negative regulation of endopeptidase activity;GO:0021953//central nervous system neuron differentiation;GO:0007165//signal transduction;GO:0010977//negative regulation of neuron projection development GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005509//calcium ion binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0005615//extracellular space;GO:0016528//sarcoplasm;GO:0031594//neuromuscular junction;GO:0033268//node of Ranvier;GO:0005578//proteinaceous extracellular matrix;GO:0014069//postsynaptic density 31 tr|B4DRV4|B4DRV4_HUMAN cDNA FLJ55667, highly similar to Secreted protein acidic and rich in cysteine OS=Homo sapiens PE=2 SV=1 31093 MCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRSPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQKDIDKDLVI 4390 57.5 - 180 180 12 12 0.308 0.255 0.26 109 112 110 - - - 0.274333333 0.029263174 tr|B4DRV4|B4DRV4_HUMAN 100 7.00E-123 gi|194388798|dbj|BAG61416.1| unnamed protein product [Homo sapiens] 99.53 1.00E-124 sp|P09486|SPRC_HUMAN SPARC OS=Homo sapiens GN=SPARC PE=1 SV=1 100 3.00E-122 B4DRV4 B4DRV4_HUMAN cDNA FLJ55667, highly similar to Secreted protein acidic and rich in cysteine OS=Homo sapiens PE=2 SV=1 - - - - - - - K08136|1|2e-07|56.2|rno:306404|sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) GO:0071363//cellular response to growth factor stimulus;GO:0030324//lung development;GO:0030168//platelet activation;GO:0001503//ossification;GO:0033591//response to L-ascorbic acid;GO:0045471//response to ethanol;GO:0007507//heart development;GO:0043434//response to peptide hormone stimulus;GO:0051384//response to glucocorticoid stimulus;GO:0048839//inner ear development;GO:0009629//response to gravity;GO:0042127//regulation of cell proliferation;GO:0034097//response to cytokine stimulus;GO:0007165//signal transduction;GO:0010288//response to lead ion;GO:0002576//platelet degranulation;GO:0032496//response to lipopolysaccharide;GO:0046686//response to cadmium ion;GO:0051591//response to cAMP;GO:0051592//response to calcium ion GO:0005509//calcium ion binding;GO:0050840//extracellular matrix binding;GO:0005518//collagen binding GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0005634//nucleus 32 sp|P25789|PSA4_HUMAN Proteasome subunit alpha type-4 OS=Homo sapiens GN=PSMA4 PE=1 SV=1 37964 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 221 19.2 - 17 17 5 5 1.064 0.859 0.94 7 8 8 - - - 0.954333333 0.10324889 sp|P25789|PSA4_HUMAN 100 7.00E-94 gi|156713444|ref|NP_001096138.1| proteasome subunit alpha type-4 isoform 2 [Homo sapiens] >gi|62204508|gb|AAH93069.1| PSMA4 protein [Homo sapiens] 100 2.00E-139 sp|P25789|PSA4_HUMAN Proteasome subunit alpha type-4 OS=Homo sapiens GN=PSMA4 PE=1 SV=1 100 6.00E-138 F6QQJ2 F6QQJ2_CALJA Proteasome subunit alpha type OS=Callithrix jacchus GN=LOC100387896 PE=3 SV=1 YGR135w 271 6.00E-73 COG0638 20S proteasome, alpha and beta subunits O Posttranslational modification, protein turnover, chaperones ; K02728|1|2e-139|494|ecb:100050569|20S proteasome subunit alpha 3 [EC:3.4.25.1] GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0019048//virus-host interaction;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0005515//protein binding;GO:0004298//threonine-type endopeptidase activity GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0019773//proteasome core complex, alpha-subunit complex 33 sp|Q99536|VAT1_HUMAN Synaptic vesicle membrane protein VAT-1 homolog OS=Homo sapiens GN=VAT1 PE=1 SV=2 >tr|A0A024R1Z6|A0A024R1Z6_HUMAN Vesicle amine transport protein 1 homolog (T californica), isoform CRA_a OS=Homo sapiens GN=VAT1 PE=4 SV=1 48510 MSDEREVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRNLMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLLVPGPEKEN 576 32.1 - 28 28 9 9 0.965 0.847 0.956 20 20 18 - - - 0.922666667 0.065683585 sp|Q99536|VAT1_HUMAN 100 0 gi|32425722|gb|AAH01913.2| VAT1 protein [Homo sapiens] 100 0 sp|Q99536|VAT1_HUMAN Synaptic vesicle membrane protein VAT-1 homolog OS=Homo sapiens GN=VAT1 PE=1 SV=2 100 2.00E-143 B0AZP7 B0AZP7_HUMAN Synaptic vesicle membrane protein VAT-1 homolog OS=Homo sapiens GN=VAT1 PE=2 SV=1 Rv1912c 180 4.00E-45 COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases CR Energy production and conversion ; General function prediction only ; K00540|1|0.0|697|hsa:10493|[EC:1.-.-.-]!K00344|3|1e-26|121|rno:362061|NADPH2:quinone reductase [EC:1.6.5.5] GO:0055085//transmembrane transport;GO:0055114//oxidation-reduction process;GO:0006836//neurotransmitter transport;GO:0010637//negative regulation of mitochondrial fusion;GO:0015844//monoamine transport GO:0008270//zinc ion binding;GO:0015238//drug transmembrane transporter activity;GO:0008504//monoamine transmembrane transporter activity;GO:0016491//oxidoreductase activity;GO:0000166//nucleotide binding GO:0016021//integral to membrane;GO:0070083//clathrin-sculpted monoamine transport vesicle membrane;GO:0005741//mitochondrial outer membrane 34 tr|B3KSH8|B3KSH8_HUMAN cDNA FLJ36241 fis, clone THYMU2001622, highly similar to Inositol polyphosphate 1-phosphatase (EC 3.1.3.57) OS=Homo sapiens PE=2 SV=1 51825 MSDILRELLCVSEKAANIARACRQQEALFQLLIEEKKEGEKNKKFAVDFKTLADVLVQEVIKQNMENKFPGLEKNIFGEESNEFTNDWGEKITLRLCSTEEETAELLSKVLNGNKVASEALARVVHQDVAFTDPTLDSTEINVPQDILGIWVDPIDSTYQYIKGSADIKSNQGIFPCGLQCVTILIGVYDIQTGVPLMGVINQPFVSRDPNTLRWKGQCYWGLSYMGTNMHSLQPTISRRNGSETHTGNTGSEAAFSPSFSAVISTSEKETIKAALSRVCGDRIFGAAGAGYKSLCVVQGLVDIYIFSEDTTFKWDSCAAHAILRAMGGGIVDLKECLERNPETGLDLPQLVYHVENEGAAGVDRWANKGGLIAYRSRKRLETFLSLLVQNLAPAETHT 89 3 11 2 2 1 1 0.783 0.948 0.72 2 2 2 - - - 0.817 0.117741242 tr|B3KSH8|B3KSH8_HUMAN 100 1.00E-53 gi|119631275|gb|EAX10870.1| inositol polyphosphate-1-phosphatase, isoform CRA_b [Homo sapiens] 99.75 0 sp|P49441|INPP_HUMAN Inositol polyphosphate 1-phosphatase OS=Homo sapiens GN=INPP1 PE=1 SV=1 100 6.00E-08 C9J2N5 C9J2N5_HUMAN Inositol polyphosphate 1-phosphatase (Fragment) OS=Homo sapiens GN=INPP1 PE=4 SV=1 PA5175 51.6 3.00E-06 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase P Inorganic ion transport and metabolism ; K01107|1|0.0|799|hsa:3628|inositol polyphosphate 1-phosphatase [EC:3.1.3.57] GO:0046854//phosphatidylinositol phosphorylation;GO:0007165//signal transduction GO:0046872//metal ion binding;GO:0004441//inositol-1,4-bisphosphate 1-phosphatase activity - 35 tr|B2R6U9|B2R6U9_HUMAN Delta-like protein OS=Homo sapiens PE=2 SV=1 159434 MRSPRTRGRSGRPLSLLLALLCALRAKVCGASGQFELEILSMQNVNGELQNGNCCGGARNPGDRKCTRDECDTYFKVCLKEYQSRVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSNDTVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSYIPILDDQCFVHPCTGVGECRSSSLQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEYSIYIACEPSPSANNEIHVAISAEDIRDDGNPIKEITDKIIDLVSKRDGNSSLIAAVAEVRVQRRPLKNRTDFLVPLLSSVLTVAWICCLVTAFYWCLRKRRKPGSHTHSASEDNTTNNVREQLNQIKNPIEKHGANTVPIKDYENKNSKMSKIRTHNSEVEEDDMDKHQQKARFAKQPAYTLVDREEKPPNGTPTKHPNWTNKQDNRDLESAQSLNRMEYIV 51 2.1 2 2 2 2 2 1.305 1.141 0.931 2 2 2 - - - 1.125666667 0.187470887 tr|B2R6U9|B2R6U9_HUMAN 100 0 gi|189053430|dbj|BAG35596.1| unnamed protein product [Homo sapiens] 99.92 0 sp|P78504|JAG1_HUMAN Protein jagged-1 OS=Homo sapiens GN=JAG1 PE=1 SV=3 100 0 B2R6U9 B2R6U9_HUMAN cDNA, FLJ93126, highly similar to Homo sapiens jagged 1 (Alagille syndrome) (JAG1), mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K06052|1|0.0|2437|hsa:182|jagged GO:0001525//angiogenesis;GO:0035909//aorta morphogenesis;GO:0060411//cardiac septum morphogenesis;GO:0061309//cardiac neural crest cell development involved in outflow tract morphogenesis;GO:0042127//regulation of cell proliferation;GO:0045665//negative regulation of neuron differentiation;GO:0003215//cardiac right ventricle morphogenesis;GO:0072017//distal tubule development;GO:0097150//neuronal stem cell maintenance;GO:0030334//regulation of cell migration;GO:0045446//endothelial cell differentiation;GO:0072070//loop of Henle development;GO:0045747//positive regulation of Notch signaling pathway;GO:0045445//myoblast differentiation;GO:0061444//endocardial cushion cell development;GO:0002011//morphogenesis of an epithelial sheet;GO:0045639//positive regulation of myeloid cell differentiation;GO:0007220//Notch receptor processing;GO:0061156//pulmonary artery morphogenesis;GO:0001709//cell fate determination;GO:0032495//response to muramyl dipeptide;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0061314//Notch signaling involved in heart development;GO:0030216//keratinocyte differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0003184//pulmonary valve morphogenesis;GO:0042491//auditory receptor cell differentiation;GO:2000737//negative regulation of stem cell differentiation GO:0005198//structural molecule activity;GO:0008083//growth factor activity;GO:0005509//calcium ion binding;GO:0005112//Notch binding GO:0005576//extracellular region;GO:0045177//apical part of cell;GO:0005887//integral to plasma membrane 36 tr|A0A024QZK7|A0A024QZK7_HUMAN Hexokinase 1, isoform CRA_c OS=Homo sapiens GN=HK1 PE=3 SV=1 121818 MGQICQRESATAAEKPKLHLLAESEIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 102 7.1 5 8 8 6 6 0.894 0.562 0.522 4 4 4 - * * 0.659333333 0.204209043 tr|A0A024QZK7|A0A024QZK7_HUMAN 100 0 gi|15991829|ref|NP_277032.1| hexokinase-1 isoform HKI-ta/tb [Homo sapiens] >gi|15991831|ref|NP_277033.1| hexokinase-1 isoform HKI-ta/tb [Homo sapiens] >gi|8996017|gb|AAF82319.1|AAF82319 hexokinase 1 isoform ta/tb [Homo sapiens] >gi|119574706|gb|EAW54321.1| hexokinase 1, isoform CRA_c [Homo sapiens] >gi|119574707|gb|EAW54322.1| hexokinase 1, isoform CRA_c [Homo sapiens] 99.89 0 sp|P19367|HXK1_HUMAN Hexokinase-1 OS=Homo sapiens GN=HK1 PE=1 SV=3 100 4.00E-44 F7I8J4 F7I8J4_CALJA Uncharacterized protein (Fragment) OS=Callithrix jacchus PE=3 SV=1 SPAC24H6.04 268 5.00E-71 COG5026 Hexokinase G Carbohydrate transport and metabolism ; K00844|1|0.0|1892|ptr:450505|hexokinase [EC:2.7.1.1] GO:0055085//transmembrane transport;GO:0015758//glucose transport;GO:0006096//glycolysis;GO:0044281//small molecule metabolic process GO:0004396//hexokinase activity;GO:0005524//ATP binding;GO:0005515//protein binding GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005741//mitochondrial outer membrane;GO:0045121//membrane raft 37 tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN Peroxiredoxin-1 (Fragment) OS=Homo sapiens GN=PRDX1 PE=4 SV=1 23394 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGE 292 36.8 1 35 18 6 4 0.766 0.566 0.591 9 9 9 * * * 0.641 0.108972474 tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN 100 2.00E-96 gi|119627382|gb|EAX06977.1| peroxiredoxin 1, isoform CRA_b [Homo sapiens] 100 2.00E-97 sp|Q06830|PRDX1_HUMAN Peroxiredoxin-1 OS=Homo sapiens GN=PRDX1 PE=1 SV=1 100 4.00E-96 H2PYX4 H2PYX4_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000117450 PE=4 SV=1 SPCC576.03c 228 3.00E-60 COG0450 Peroxiredoxin O Posttranslational modification, protein turnover, chaperones ; K13279|1|2e-97|354|hsa:5052|peroxiredoxin 1 [EC:1.11.1.15] GO:0001501//skeletal system development;GO:0032872//regulation of stress-activated MAPK cascade;GO:0042744//hydrogen peroxide catabolic process;GO:0034101//erythrocyte homeostasis;GO:0042267//natural killer cell mediated cytotoxicity;GO:0008283//cell proliferation;GO:0019430//removal of superoxide radicals;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0055114//oxidation-reduction process GO:0020037//heme binding;GO:0008379//thioredoxin peroxidase activity;GO:0042803//protein homodimerization activity GO:0005759//mitochondrial matrix;GO:0005719//nuclear euchromatin;GO:0042470//melanosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005782//peroxisomal matrix 38 tr|V9HW65|V9HW65_HUMAN Annexin OS=Homo sapiens GN=HEL-S-270 PE=2 SV=1 48819 MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMASRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD 324 25.7 1 22 22 7 7 0.895 0.818 0.614 13 15 13 - * * 0.775666667 0.145204454 tr|V9HW65|V9HW65_HUMAN 100 3.00E-162 gi|119597993|gb|EAW77587.1| annexin A2, isoform CRA_c [Homo sapiens] 99.71 0 sp|Q5R5A0|ANXA2_PONAB Annexin A2 OS=Pongo abelii GN=ANXA2 PE=2 SV=1 100 1.00E-128 H0YMU9 H0YMU9_HUMAN Annexin OS=Homo sapiens GN=ANXA2 PE=3 SV=1 - - - - - - - - GO:0001501//skeletal system development;GO:0001525//angiogenesis;GO:0051099//positive regulation of binding;GO:0007589//body fluid secretion;GO:0031340//positive regulation of vesicle fusion;GO:0042730//fibrinolysis;GO:0030199//collagen fibril organization;GO:0071229//cellular response to acid GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0017137//Rab GTPase binding;GO:0005509//calcium ion binding;GO:0008092//cytoskeletal protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0004859//phospholipase inhibitor activity GO:0005604//basement membrane;GO:0043220//Schmidt-Lanterman incisure;GO:0042470//melanosome;GO:0019897//extrinsic to plasma membrane;GO:0042383//sarcolemma;GO:0043234//protein complex;GO:0005769//early endosome;GO:0030496//midbody;GO:0048471//perinuclear region of cytoplasm;GO:0005811//lipid particle;GO:0035749//myelin sheath adaxonal region 39 sp|P34096|RNAS4_HUMAN Ribonuclease 4 OS=Homo sapiens GN=RNASE4 PE=1 SV=3 >tr|Q53XB4|Q53XB4_HUMAN Full-length cDNA clone CS0DF032YM23 of Fetal brain of Homo sapiens (human) OS=Homo sapiens GN=RAB1 PE=2 SV=1 19111 MALQRTHSLLLLLLLTLLGLGLVQPSYGQDGMYQRFLRQHVHPEETGGSDRYCNLMMQRRKMTLYHCKRFNTFIHEDIWNIRSICSTTNIQCKNGKMNCHEGVVKVTDCRDTGSSRAPNCRYRAIASTRRVVIACEGNPQVPVHFDG 65 8.8 - 4 4 1 1 0.715 1.462 1.473 3 3 3 - - - 1.216666667 0.43449089 sp|P34096|RNAS4_HUMAN 100 3.00E-74 gi|119586853|gb|EAW66449.1| hCG2044782, isoform CRA_b [Homo sapiens] 100 1.00E-74 sp|P34096|RNAS4_HUMAN Ribonuclease 4 OS=Homo sapiens GN=RNASE4 PE=1 SV=3 100 4.00E-73 Q53XB4 Q53XB4_HUMAN Full-length cDNA clone CS0DF032YM23 of Fetal brain of Homo sapiens (human) OS=Homo sapiens GN=hCG_2044782 PE=2 SV=1 - - - - - - - K01172|1|1e-74|277|hsa:6038|[EC:3.1.27.-] GO:0006379//mRNA cleavage GO:0004522//pancreatic ribonuclease activity;GO:0003676//nucleic acid binding GO:0005576//extracellular region 40 tr|B2R984|B2R984_HUMAN cDNA, FLJ94268, highly similar to Homo sapiens histone 1, H1e (HIST1H1E), mRNA OS=Homo sapiens PE=2 SV=1 41045 MSETAPAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGAAKKPKKVTGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKKAKAAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK 88 9.6 5 5 5 2 2 1.035 1.383 0.799 3 3 3 - - - 1.072333333 0.293784502 tr|B2R984|B2R984_HUMAN 100 1.00E-26 gi|332228256|ref|XP_003263310.1| PREDICTED: histone H1.4-like [Nomascus leucogenys] 100 1.00E-27 sp|P10412|H14_HUMAN Histone H1.4 OS=Homo sapiens GN=HIST1H1E PE=1 SV=2 100 1.00E-23 H2QSF7 H2QSF7_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000187837 PE=3 SV=1 - - - - - - - K11275|1|1e-27|123|cfa:488269|histone H1/5 GO:0016584//nucleosome positioning GO:0003677//DNA binding;GO:0005515//protein binding GO:0005694//chromosome;GO:0005634//nucleus 41 tr|A8K701|A8K701_HUMAN cDNA FLJ77574, highly similar to Homo sapiens iduronidase, alpha-L- (IDUA), mRNA OS=Homo sapiens PE=2 SV=1 77220 MRPLRPRAALLALLASLLAAPPVAPAEAPHLVQVDAARALWPLRRFWRSTGFCPPLPHSQADQYVLSWDQQLNLAYVGAVPHRGIKQVRTHWLLELVTTRGSTGRGLSYNFTHLDGYLDLLRENQLLPGFELMGSASGHFTDFEDKQQVFEWKDLVSSLARRYIGRYGLAHVSKWNFETWNEPDHHDFDNVSMTMQGFLNYYNACSEGLRAASPALRLGGPGDSFHTPPRSPLSWGLLRHCHDGTNFFTGEAGVRLDYISLHRKGARSSISILEQEKVVAQQIRQLFPKFADTPIYNDEADPLVGWSLPQPWRADVTYAAMVVKVIAQHQNLLLANTTSAFPYALLSNDNAFLSYHPHTFAQRTLTARFQVNNTRPPHVQLLRKPVLTAMGLLALLDEEQLWAEVSQAGTVLDSNHTVGVLASAHRPQGPADAWRAAVLIYASDDTRAHPNRSVAVTLRLRGVPPGPGLVYVTRYLDNGLCSPDGEWRRLGRPVFPTAEQFRRMRAAEDPVAAAPRPLPAGGRLTLRPALRLPSLLLVHVCARPEKPPGQVTRLRALPLTQGQLVLVWSDEHVGSKCLWTYEIQFSQDGKAYTPVSRKPSTFNLFVFSPDTGAVSGSYRVRALDYWARPGPFSDPVPYLEVPVPRGPPSPGNP 126 8.9 1 8 8 4 4 1.406 1.438 1.569 4 4 4 - - * 1.471 0.086365502 tr|A8K701|A8K701_HUMAN 100 0 gi|158257064|dbj|BAF84505.1| unnamed protein product [Homo sapiens] 99.51 0 sp|P35475|IDUA_HUMAN Alpha-L-iduronidase OS=Homo sapiens GN=IDUA PE=1 SV=2 100 0 A8K701 A8K701_HUMAN cDNA FLJ77574, highly similar to Homo sapiens iduronidase, alpha-L- (IDUA), mRNA OS=Homo sapiens PE=2 SV=1 BH1068 64.3 6.00E-10 COG3664 Beta-xylosidase G Carbohydrate transport and metabolism ; K01217|1|0.0|1177|hsa:3425|L-iduronidase [EC:3.2.1.76] GO:0030207//chondroitin sulfate catabolic process;GO:0005984//disaccharide metabolic process;GO:0048705//skeletal system morphogenesis;GO:0048878//chemical homeostasis;GO:0000902//cell morphogenesis;GO:0035108//limb morphogenesis;GO:0044281//small molecule metabolic process;GO:0007040//lysosome organization GO:0043169//cation binding;GO:0003940//L-iduronidase activity GO:0043202//lysosomal lumen 42 tr|F5H0C8|F5H0C8_HUMAN Enolase OS=Homo sapiens GN=ENO2 PE=1 SV=1 41110 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSLELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL 609 16.5 2 34 15 4 2 0.782 0.759 0.732 11 10 11 - * * 0.757666667 0.025026652 tr|F5H0C8|F5H0C8_HUMAN 99.04 5.00E-52 gi|395847555|ref|XP_003796434.1| PREDICTED: gamma-enolase [Otolemur garnettii] 98.6 8.00E-125 sp|P09104|ENOG_HUMAN Gamma-enolase OS=Homo sapiens GN=ENO2 PE=1 SV=3 100 0 F5H0C8 F5H0C8_HUMAN Enolase OS=Homo sapiens GN=ENO2 PE=3 SV=1 YGR254w 294 2.00E-79 COG0148 Enolase G Carbohydrate transport and metabolism ; K01689|1|8e-125|446|hsa:2026|enolase [EC:4.2.1.11] GO:0040010//positive regulation of growth rate;GO:0008340//determination of adult lifespan;GO:0040035//hermaphrodite genitalia development;GO:0014070//response to organic cyclic compound;GO:0002119//nematode larval development;GO:0006096//glycolysis;GO:0006094//gluconeogenesis;GO:0032355//response to estradiol stimulus;GO:0042493//response to drug;GO:0006898//receptor-mediated endocytosis;GO:0044281//small molecule metabolic process;GO:0009792//embryo development ending in birth or egg hatching;GO:0040018//positive regulation of multicellular organism growth GO:0000287//magnesium ion binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0004634//phosphopyruvate hydratase activity GO:0000015//phosphopyruvate hydratase complex;GO:0009986//cell surface;GO:0001917//photoreceptor inner segment;GO:0005886//plasma membrane;GO:0043204//perikaryon 43 sp|O95782|AP2A1_HUMAN AP-2 complex subunit alpha-1 OS=Homo sapiens GN=AP2A1 PE=1 SV=3 125597 MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCVSLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAIREEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRALLLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLEEMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLLGLRAAPPPAAPPASAGAGNLLVDVFDGPAAQPSLGPTPEEAFLSELEPPAPESPMALLADPAPAADPGPEDIGPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFSPTVVHPGDLQTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLLSVRFRYGGAPQALTLKLPVTINKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMDAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRTSKEPVSRHLCELLAQQF 176 7.4 - 13 13 7 7 1.275 0.623 0.626 7 7 6 - - * 0.841333333 0.375569346 sp|O95782|AP2A1_HUMAN 100 2.00E-33 gi|441630576|ref|XP_003269734.2| PREDICTED: AP-2 complex subunit alpha-1 [Nomascus leucogenys] 100 0 sp|O95782|AP2A1_HUMAN AP-2 complex subunit alpha-1 OS=Homo sapiens GN=AP2A1 PE=1 SV=3 100 0 G3RTG9 G3RTG9_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=AP2A1 PE=4 SV=1 - - - - - - - K11824|1|0.0|1790|hsa:160|AP-2 complex subunit alpha GO:0007411//axon guidance;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0016032//viral reproduction;GO:0006886//intracellular protein transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050690//regulation of defense response to virus by virus;GO:0006897//endocytosis;GO:0007268//synaptic transmission;GO:0006895//Golgi to endosome transport GO:0008022//protein C-terminus binding;GO:0008565//protein transporter activity GO:0030122//AP-2 adaptor complex;GO:0016323//basolateral plasma membrane;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0005829//cytosol;GO:0016324//apical plasma membrane 44 sp|Q9NZN4|EHD2_HUMAN EH domain-containing protein 2 OS=Homo sapiens GN=EHD2 PE=1 SV=2 >tr|A0A024R0S6|A0A024R0S6_HUMAN EH-domain containing 2, isoform CRA_a OS=Homo sapiens GN=EHD2 PE=4 SV=1 73158 MFSWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPMVLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDKPFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMGPFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHKGSAE 241 6.8 - 10 10 3 3 0.902 0.762 0.583 10 10 10 - * * 0.749 0.159896842 sp|Q9NZN4|EHD2_HUMAN 100 0 gi|21361462|ref|NP_055416.2| EH domain-containing protein 2 [Homo sapiens] >gi|57015322|sp|Q9NZN4.2|EHD2_HUMAN RecName: Full=EH domain-containing protein 2; AltName: Full=PAST homolog 2 >gi|17981587|gb|AAL51078.1|AF454952_1 EH domain-containing protein-2 [Homo sapiens] >gi|15680192|gb|AAH14445.1| EH-domain containing 2 [Homo sapiens] >gi|119577909|gb|EAW57505.1| EH-domain containing 2, isoform CRA_a [Homo sapiens] >gi|119577910|gb|EAW57506.1| EH-domain containing 2, isoform CRA_a [Homo sapiens] 100 0 sp|Q9NZN4|EHD2_HUMAN EH domain-containing protein 2 OS=Homo sapiens GN=EHD2 PE=1 SV=2 100 0 G3S6K4 G3S6K4_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=EHD2 PE=4 SV=1 DR1235 61.6 4.00E-09 COG0699 Predicted GTPases (dynamin-related) R General function prediction only ; K12469|1|0.0|1076|hsa:30846|EH domain-containing protein 2 GO:0086036//regulation of cardiac muscle cell membrane potential;GO:0072661//protein targeting to plasma membrane;GO:0032456//endocytic recycling;GO:0006184//GTP catabolic process;GO:0007596//blood coagulation;GO:0006897//endocytosis;GO:0051260//protein homooligomerization;GO:0030866//cortical actin cytoskeleton organization GO:0005525//GTP binding;GO:0005509//calcium ion binding;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0003924//GTPase activity;GO:0005524//ATP binding GO:0055038//recycling endosome membrane;GO:0030139//endocytic vesicle;GO:0005886//plasma membrane;GO:0005634//nucleus 45 sp|P50479|PDLI4_HUMAN PDZ and LIM domain protein 4 OS=Homo sapiens GN=PDLIM4 PE=1 SV=2 39844 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV 81 10 - 3 3 2 2 0.856 --- --- 2 1 1 - - - 0.856 - sp|P50479|PDLI4_HUMAN 100 1.00E-172 gi|19923181|ref|NP_003678.2| PDZ and LIM domain protein 4 isoform 1 [Homo sapiens] >gi|20141642|sp|P50479.2|PDLI4_HUMAN RecName: Full=PDZ and LIM domain protein 4; AltName: Full=LIM protein RIL; AltName: Full=Reversion-induced LIM protein >gi|4960214|gb|AAD34646.1|AF154335_1 reversion-induced LIM protein [Homo sapiens] >gi|5020416|gb|AAD38070.1|AF153882_1 reversion-induced LIM protein [Homo sapiens] >gi|119582755|gb|EAW62351.1| PDZ and LIM domain 4, isoform CRA_c [Homo sapiens] 100 1.00E-173 sp|P50479|PDLI4_HUMAN PDZ and LIM domain protein 4 OS=Homo sapiens GN=PDLIM4 PE=1 SV=2 100 3.00E-172 H2QRG2 H2QRG2_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000131435 PE=4 SV=1 - - - - - - - K08202|1|5e-17|89.0|oaa:100079308|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5!K05743|2|1e-06|53.9|xtr:780362|LIM domain kinase 1 [EC:2.7.11.1] - GO:0008270//zinc ion binding;GO:0005515//protein binding - 46 tr|F1C4A7|F1C4A7_HUMAN Monocyte differentiation antigen CD14 OS=Homo sapiens GN=CD14 PE=4 SV=1 43702 MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIHAGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKELTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQAHSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGIETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACARSTLSVGVSGTLVLLQGARGFA 126 10.4 2 6 6 3 3 2.021 1.033 --- 4 2 1 - - - 1.527 0.6986215 tr|F1C4A7|F1C4A7_HUMAN 100 7.00E-61 gi|15667229|gb|AAL02401.1| CD14 antigen [Homo sapiens] 99.73 0 sp|P08571|CD14_HUMAN Monocyte differentiation antigen CD14 OS=Homo sapiens GN=CD14 PE=1 SV=2 100 4.00E-113 D6RFL4 D6RFL4_HUMAN Monocyte differentiation antigen CD14, urinary form (Fragment) OS=Homo sapiens GN=CD14 PE=4 SV=1 - - - - - - - K04391|1|0.0|675|hsa:929|CD14 antigen GO:0006909//phagocytosis;GO:0032760//positive regulation of tumor necrosis factor production;GO:0008063//Toll signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0050715//positive regulation of cytokine secretion;GO:0071223//cellular response to lipoteichoic acid;GO:0006915//apoptotic process;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB cascade;GO:0006954//inflammatory response;GO:0034138//toll-like receptor 3 signaling pathway;GO:0009408//response to heat;GO:0045807//positive regulation of endocytosis;GO:0071222//cellular response to lipopolysaccharide GO:0070891//lipoteichoic acid binding;GO:0001530//lipopolysaccharide binding;GO:0001847//opsonin receptor activity;GO:0016019//peptidoglycan receptor activity GO:0045121//membrane raft;GO:0005615//extracellular space;GO:0031225//anchored to membrane;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0010008//endosome membrane 47 tr|A0A024RDQ0|A0A024RDQ0_HUMAN Heat shock 105kDa/110kDa protein 1, isoform CRA_a OS=Homo sapiens GN=HSPH1 PE=3 SV=1 116698 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECYPNEKNSVNMDLD 129 5.7 3 7 3 3 2 0.741 0.873 0.556 2 2 2 * - - 0.723333333 0.159236721 tr|A0A024RDQ0|A0A024RDQ0_HUMAN 100 2.00E-56 gi|426375109|ref|XP_004054390.1| PREDICTED: heat shock protein 105 kDa isoform 4 [Gorilla gorilla gorilla] 94.87 0 sp|Q92598|HS105_HUMAN Heat shock protein 105 kDa OS=Homo sapiens GN=HSPH1 PE=1 SV=1 100 4.00E-14 B4DY72 B4DY72_HUMAN Heat shock protein 105 kDa OS=Homo sapiens GN=HSPH1 PE=2 SV=1 YBR169c 474 4.00E-133 COG0443 Molecular chaperone O Posttranslational modification, protein turnover, chaperones ; K09485|1|0.0|1634|hsa:10808|heat shock protein 110kDa GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0051135//positive regulation of NK T cell activation;GO:0051085//chaperone mediated protein folding requiring cofactor;GO:0006986//response to unfolded protein GO:0005524//ATP binding;GO:0043014//alpha-tubulin binding GO:0005730//nucleolus;GO:0005874//microtubule;GO:0005576//extracellular region;GO:0005737//cytoplasm 48 sp|P24593|IBP5_HUMAN Insulin-like growth factor-binding protein 5 OS=Homo sapiens GN=IGFBP5 PE=1 SV=1 >tr|A0A024R433|A0A024R433_HUMAN Insulin-like growth factor binding protein 5, isoform CRA_a OS=Homo sapiens GN=IGFBP5 PE=4 SV=1 38269 MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE 225 17.3 - 22 22 4 4 0.431 0.362 0.35 6 7 7 * * * 0.381 0.043714986 sp|P24593|IBP5_HUMAN 100 2.00E-147 gi|10834982|ref|NP_000590.1| insulin-like growth factor-binding protein 5 precursor [Homo sapiens] >gi|124069|sp|P24593.1|IBP5_HUMAN RecName: Full=Insulin-like growth factor-binding protein 5; Short=IBP-5; Short=IGF-binding protein 5; Short=IGFBP-5; Flags: Precursor >gi|184818|gb|AAA53505.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|184820|gb|AAD04730.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|505589|gb|AAA72051.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|3005764|gb|AAC09368.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|15079241|gb|AAH11453.1| Insulin-like growth factor binding protein 5 [Homo sapiens] >gi|42416964|gb|AAS16353.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|54696280|gb|AAV38512.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|54696282|gb|AAV38513.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|119590980|gb|EAW70574.1| insulin-like growth factor binding protein 5, isoform CRA_a [Homo sapiens] >gi|119590981|gb|EAW70575.1| insulin-like growth factor binding protein 5, isoform CRA_a [Homo sapiens] 100 2.00E-148 sp|P24593|IBP5_HUMAN Insulin-like growth factor-binding protein 5 OS=Homo sapiens GN=IGFBP5 PE=1 SV=1 99.61 9.00E-147 F6YKJ0 F6YKJ0_MACMU Uncharacterized protein OS=Macaca mulatta GN=Mmu.4685 PE=4 SV=1 - - - - - - - K10138|1|1e-56|219|mcc:696868|insulin-like growth factor-binding protein 3 GO:0017148//negative regulation of translation;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0001558//regulation of cell growth;GO:0071407//cellular response to organic cyclic compound;GO:0048630//skeletal muscle tissue growth;GO:0051146//striated muscle cell differentiation;GO:0031069//hair follicle morphogenesis;GO:0044342//type B pancreatic cell proliferation;GO:0014912//negative regulation of smooth muscle cell migration;GO:0045668//negative regulation of osteoblast differentiation;GO:0071320//cellular response to cAMP;GO:0060056//mammary gland involution;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway;GO:0010906//regulation of glucose metabolic process;GO:0042593//glucose homeostasis;GO:0051897//positive regulation of protein kinase B signaling cascade GO:0031994//insulin-like growth factor I binding;GO:0001968//fibronectin binding GO:0016942//insulin-like growth factor binding protein complex;GO:0005622//intracellular 49 tr|Q9NSD0|Q9NSD0_HUMAN Protein S OS=Homo sapiens PE=2 SV=1 89278 MSKQQASQVLVRKRRANSLLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIYHSAWLLIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNNTVPFAVSLVDSTSEKSQDILLSVENTVIYRIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVWKKTKNS 197 9.7 2 13 13 6 6 1.88 2.093 2.53 7 7 7 - * * 2.167666667 0.331370387 tr|Q9NSD0|Q9NSD0_HUMAN 100 2.00E-35 gi|27531052|dbj|BAC54135.1| Protein S [Homo sapiens] 99.38 0 sp|P07225|PROS_HUMAN Vitamin K-dependent protein S OS=Homo sapiens GN=PROS1 PE=1 SV=1 100 4.00E-25 Q8IXD2 Q8IXD2_HUMAN Protein S (Fragment) OS=Homo sapiens GN=PROS1 PE=2 SV=1 - - - - - - - K03908|1|0.0|1337|hsa:5627|protein S GO:0030168//platelet activation;GO:0010951//negative regulation of endopeptidase activity;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0050900//leukocyte migration;GO:0042730//fibrinolysis;GO:0030449//regulation of complement activation;GO:0002576//platelet degranulation;GO:0006508//proteolysis;GO:0043687//post-translational protein modification;GO:0045087//innate immune response GO:0005509//calcium ion binding;GO:0004866//endopeptidase inhibitor activity GO:0000139//Golgi membrane;GO:0031093//platelet alpha granule lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005576//extracellular region;GO:0005796//Golgi lumen 50 tr|B4DDB6|B4DDB6_HUMAN Heterogeneous nuclear ribonucleoprotein A3, isoform CRA_a OS=Homo sapiens GN=HNRPA3 PE=2 SV=1 43623 MEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSRRF 85 13.5 2 5 4 4 3 1.16 1.559 1.569 3 3 3 - - - 1.429333333 0.233303093 tr|B4DDB6|B4DDB6_HUMAN 100 7.00E-107 gi|119631468|gb|EAX11063.1| heterogeneous nuclear ribonucleoprotein A3, isoform CRA_a [Homo sapiens] >gi|119631470|gb|EAX11065.1| heterogeneous nuclear ribonucleoprotein A3, isoform CRA_a [Homo sapiens] 100 8.00E-106 sp|Q6URK4|ROA3_RAT Heterogeneous nuclear ribonucleoprotein A3 OS=Rattus norvegicus GN=Hnrnpa3 PE=1 SV=1 100 2.00E-104 Q3UZG3 Q3UZG3_MOUSE Putative uncharacterized protein OS=Mus musculus GN=Hnrnpa3 PE=2 SV=1 SPAC140.02 65.5 1.00E-10 COG0724 RNA-binding proteins (RRM domain) R General function prediction only ; K12741|1|8e-108|390|mmu:229279|heterogeneous nuclear ribonucleoprotein A1/A3 GO:0000398//mRNA splicing, via spliceosome;GO:0051028//mRNA transport GO:0003729//mRNA binding;GO:0000166//nucleotide binding;GO:0051033//RNA transmembrane transporter activity GO:0043005//neuron projection;GO:0005730//nucleolus;GO:0071013//catalytic step 2 spliceosome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm 51 tr|A0A024R228|A0A024R228_HUMAN Heterogeneous nuclear ribonucleoprotein K, isoform CRA_d OS=Homo sapiens GN=HNRPK PE=4 SV=1 58468 METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQVEYHSYYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSGKFF 265 11 6 16 16 4 4 1.236 1.028 1.069 7 7 7 - - - 1.111 0.11017713 tr|A0A024R228|A0A024R228_HUMAN 100 1.00E-84 gi|348578485|ref|XP_003475013.1| PREDICTED: heterogeneous nuclear ribonucleoprotein K-like [Cavia porcellus] 98.7 0 sp|P61980|HNRPK_RAT Heterogeneous nuclear ribonucleoprotein K OS=Rattus norvegicus GN=Hnrnpk PE=1 SV=1 100 3.00E-84 H0V4H8 H0V4H8_CAVPO Uncharacterized protein OS=Cavia porcellus GN=LOC100729110 PE=4 SV=1 - - - - - - - K12886|1|0.0|648|rno:117282|heterogeneous nuclear ribonucleoprotein K GO:0072369//regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0007165//signal transduction;GO:0010988//regulation of low-density lipoprotein particle clearance;GO:0000398//mRNA splicing, via spliceosome;GO:0045716//positive regulation of low-density lipoprotein particle receptor biosynthetic process GO:0005515//protein binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003697//single-stranded DNA binding GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0071013//catalytic step 2 spliceosome;GO:0000790//nuclear chromatin 52 tr|Q5U043|Q5U043_HUMAN Alcohol dehydrogenase 5 (Class III), chi polypeptide OS=Homo sapiens PE=2 SV=1 50558 MANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINPQDLSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSGKSIRTVVKI 190 20.3 2 11 11 5 5 0.893 0.877 1.126 8 8 8 - - - 0.965333333 0.139371207 tr|Q5U043|Q5U043_HUMAN 100 0 gi|54696528|gb|AAV38636.1| alcohol dehydrogenase 5 (class III), chi polypeptide [Homo sapiens] 99.73 0 sp|P11766|ADHX_HUMAN Alcohol dehydrogenase class-3 OS=Homo sapiens GN=ADH5 PE=1 SV=4 100 0 Q5U043 Q5U043_HUMAN Alcohol dehydrogenase 5 (Class III), chi polypeptide OS=Homo sapiens PE=2 SV=1 YPO1502 523 3.00E-148 COG1062 Zn-dependent alcohol dehydrogenases, class III C Energy production and conversion ; K00121|1|0.0|700|hsa:128|S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] GO:0003016//respiratory system process;GO:0006069//ethanol oxidation;GO:0001523//retinoid metabolic process;GO:0051409//response to nitrosative stress;GO:0051775//response to redox state;GO:0046294//formaldehyde catabolic process;GO:0045777//positive regulation of blood pressure;GO:0006068//ethanol catabolic process;GO:0007568//aging;GO:0032496//response to lipopolysaccharide;GO:0018119//peptidyl-cysteine S-nitrosylation GO:0008270//zinc ion binding;GO:0018467//formaldehyde dehydrogenase activity;GO:0051903//S-(hydroxymethyl)glutathione dehydrogenase activity;GO:0009055//electron carrier activity;GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0000166//nucleotide binding;GO:0042803//protein homodimerization activity;GO:0005504//fatty acid binding GO:0005739//mitochondrion;GO:0005634//nucleus 53 tr|A5GZ70|A5GZ70_HUMAN Matrix metalloproteinase 3 (Fragment) OS=Homo sapiens GN=MMP3 PE=2 SV=1 10849 AVCSAYPLDGAARGEDTSMNLVQKYLENYYDLEKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDT 299 26.8 - 20 7 2 1 2.531 2.775 4.024 4 5 5 * * - 3.11 0.800893876 tr|A5GZ70|A5GZ70_HUMAN 100 9.00E-31 gi|7435842|pir||PW0052 pro-matrix metalloproteinase-3 - human (fragment) 98.59 1.00E-35 sp|P08254|MMP3_HUMAN Stromelysin-1 OS=Homo sapiens GN=MMP3 PE=1 SV=2 100 2.00E-34 G3R469 G3R469_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=MMP3 PE=4 SV=1 - - - - - - - K01394|1|1e-35|147|hsa:4314|matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17] GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0006508//proteolysis GO:0004222//metalloendopeptidase activity;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding GO:0005615//extracellular space;GO:0043231//intracellular membrane-bounded organelle;GO:0005578//proteinaceous extracellular matrix 54 tr|F8W1M8|F8W1M8_HUMAN PRKC apoptosis WT1 regulator protein (Fragment) OS=Homo sapiens GN=PAWR PE=1 SV=3 9256 MATGGYRTSSGLGGSTTDFLEEWKAKREKMRAKQNPPGPAPPGGGSSDAAGKPPAGALGTPAAAAANELNNNLPGG 57 22.4 1 2 2 1 1 0.796 0.508 --- 2 2 1 - - - 0.652 0.203646753 tr|F8W1M8|F8W1M8_HUMAN 100 6.00E-13 gi|119617752|gb|EAW97346.1| PRKC, apoptosis, WT1, regulator, isoform CRA_a [Homo sapiens] 100 7.00E-14 sp|Q96IZ0|PAWR_HUMAN PRKC apoptosis WT1 regulator protein OS=Homo sapiens GN=PAWR PE=1 SV=1 100 3.00E-12 G1QYS8 G1QYS8_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=PAWR PE=4 SV=1 - - - - - - - - GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051017//actin filament bundle assembly;GO:0042130//negative regulation of T cell proliferation;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0042094//interleukin-2 biosynthetic process;GO:0006917//induction of apoptosis;GO:0042986//positive regulation of amyloid precursor protein biosynthetic process;GO:0030889//negative regulation of B cell proliferation GO:0003714//transcription corepressor activity;GO:0043522//leucine zipper domain binding;GO:0003779//actin binding;GO:0019899//enzyme binding GO:0005884//actin filament;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005634//nucleus 55 sp|O60869|EDF1_HUMAN Endothelial differentiation-related factor 1 OS=Homo sapiens GN=EDF1 PE=1 SV=1 22747 MAESDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVETSKKWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQQGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPRAK 56 10.1 - 2 2 1 1 0.946 1.585 1.051 2 2 2 - - - 1.194 0.342661641 sp|O60869|EDF1_HUMAN 100 8.00E-53 gi|281348124|gb|EFB23708.1| hypothetical protein PANDA_020258 [Ailuropoda melanoleuca] 100 3.00E-80 sp|O60869|EDF1_HUMAN Endothelial differentiation-related factor 1 OS=Homo sapiens GN=EDF1 PE=1 SV=1 100 3.00E-63 H2QY72 H2QY72_PANTR Uncharacterized protein (Fragment) OS=Pan troglodytes GN=ENSG00000107223 PE=4 SV=1 SPBC83.17 131 5.00E-31 COG1813 Predicted transcription factor, homolog of eukaryotic MBF1 K Transcription ; K03627|1|1e-80|297|cfa:480674|putative transcription factor GO:0019216//regulation of lipid metabolic process;GO:0043388//positive regulation of DNA binding;GO:0045446//endothelial cell differentiation;GO:0007275//multicellular organismal development;GO:0045893//positive regulation of transcription, DNA-dependent GO:0005516//calmodulin binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0004402//histone acetyltransferase activity;GO:0003713//transcription coactivator activity;GO:0008168//methyltransferase activity GO:0005730//nucleolus;GO:0005669//transcription factor TFIID complex;GO:0005737//cytoplasm 56 tr|B4DMA7|B4DMA7_HUMAN cDNA FLJ58514, highly similar to Cadherin-11 OS=Homo sapiens PE=2 SV=1 97861 MGPGLAARRLRPPSRAPEITVFSAQRPCDIPSCCHLLSDQSDGWSVLQKLAASIQWVKKLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRGNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADLYGSKDTFDDDS 137 5.6 3 7 7 3 3 1.336 0.956 1.671 6 6 6 - - * 1.321 0.357735936 tr|B4DMA7|B4DMA7_HUMAN 100 0 gi|194386906|dbj|BAG59819.1| unnamed protein product [Homo sapiens] 99.45 0 sp|P55287|CAD11_HUMAN Cadherin-11 OS=Homo sapiens GN=CDH11 PE=1 SV=2 100 0 B4DMA7 B4DMA7_HUMAN cDNA FLJ58514, highly similar to Cadherin-11 OS=Homo sapiens PE=2 SV=1 - - - - - - - K06803|1|0.0|1486|mcc:708826|cadherin 11, type 2, OB-cadherin GO:0034329//cell junction assembly;GO:0007156//homophilic cell adhesion;GO:0001501//skeletal system development;GO:0001503//ossification;GO:0034332//adherens junction organization GO:0005509//calcium ion binding GO:0005886//plasma membrane;GO:0016021//integral to membrane 57 sp|P35579|MYH9_HUMAN Myosin-9 OS=Homo sapiens GN=MYH9 PE=1 SV=4 >tr|A0A024R1N1|A0A024R1N1_HUMAN Myosin, heavy polypeptide 9, non-muscle, isoform CRA_a OS=Homo sapiens GN=MYH9 PE=4 SV=1 290921 MAQQAADKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAKPAE 2328 18.2 - 101 86 30 24 0.784 0.745 0.714 60 60 59 - * * 0.747666667 0.035076108 sp|P35579|MYH9_HUMAN 100 0 gi|553596|gb|AAA59888.1| cellular myosin heavy chain, partial [Homo sapiens] 100 0 sp|P35579|MYH9_HUMAN Myosin-9 OS=Homo sapiens GN=MYH9 PE=1 SV=4 100 0 Q60FE2 Q60FE2_HUMAN MYH9 variant protein OS=Homo sapiens GN=MYH9 PE=2 SV=1 SPCC645.05c 810 0 COG5022 Myosin heavy chain Z Cytoskeleton ; K10352|1|0.0|3344|hsa:4627|myosin heavy chain GO:0030220//platelet formation;GO:0032796//uropod organization;GO:0000212//meiotic spindle organization;GO:0030048//actin filament-based movement;GO:0001701//in utero embryonic development;GO:0007411//axon guidance;GO:0051295//establishment of meiotic spindle localization;GO:0031532//actin cytoskeleton reorganization;GO:0016337//cell-cell adhesion;GO:0015031//protein transport;GO:0006200//ATP catabolic process;GO:0006509//membrane protein ectodomain proteolysis;GO:0001768//establishment of T cell polarity;GO:0043534//blood vessel endothelial cell migration;GO:0007520//myoblast fusion;GO:0050900//leukocyte migration;GO:0007132//meiotic metaphase I;GO:0000910//cytokinesis;GO:0030224//monocyte differentiation;GO:0007229//integrin-mediated signaling pathway;GO:0001525//angiogenesis;GO:0008360//regulation of cell shape;GO:0038032//termination of G-protein coupled receptor signaling pathway GO:0042803//protein homodimerization activity;GO:0000146//microfilament motor activity;GO:0030898//actin-dependent ATPase activity;GO:0043495//protein anchor;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0051015//actin filament binding;GO:0043531//ADP binding GO:0005826//actomyosin contractile ring;GO:0001772//immunological synapse;GO:0031594//neuromuscular junction;GO:0005829//cytosol;GO:0016460//myosin II complex;GO:0030863//cortical cytoskeleton;GO:0001931//uropod;GO:0008180//signalosome;GO:0032154//cleavage furrow;GO:0005913//cell-cell adherens junction;GO:0001725//stress fiber;GO:0005819//spindle;GO:0008305//integrin complex;GO:0001726//ruffle 58 tr|A0A024QZX5|A0A024QZX5_HUMAN Serpin B6 OS=Homo sapiens GN=SERPINB6 PE=1 SV=1 51856 MSAIMDVLAEANGTFALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 106 15.5 2 6 5 5 4 0.818 0.606 0.47 3 3 3 - * - 0.631333333 0.175377688 tr|A0A024QZX5|A0A024QZX5_HUMAN 100 0 gi|425876768|ref|NP_001258752.1| serpin B6 isoform d [Homo sapiens] >gi|119575508|gb|EAW55104.1| serpin peptidase inhibitor, clade B (ovalbumin), member 6, isoform CRA_e [Homo sapiens] 100 0 sp|P35237|SPB6_HUMAN Serpin B6 OS=Homo sapiens GN=SERPINB6 PE=1 SV=3 100 4.00E-142 Q8IXH2 Q8IXH2_HUMAN MSTP057 OS=Homo sapiens PE=2 SV=1 MA3388 209 5.00E-54 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K13963|1|0.0|752|hsa:5269|serpin B GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity GO:0043234//protein complex;GO:0005813//centrosome;GO:0005829//cytosol 59 tr|Q6FH17|Q6FH17_HUMAN ARF6 protein OS=Homo sapiens GN=ARF6 PE=2 SV=1 24472 MGKVLSKIFGNKEMWILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS 74 5.7 2 4 4 1 1 1.375 0.736 1.171 2 2 2 - - - 1.094 0.326384742 tr|Q6FH17|Q6FH17_HUMAN 100 1.00E-99 gi|49456833|emb|CAG46737.1| ARF6 [Homo sapiens] 99.43 2.00E-99 sp|Q007T5|ARF6_PIG ADP-ribosylation factor 6 OS=Sus scrofa GN=ARF6 PE=2 SV=1 100 3.00E-99 Q6FH17 Q6FH17_HUMAN ARF6 protein OS=Homo sapiens GN=ARF6 PE=2 SV=1 YDL137w 256 2.00E-68 COG1100 GTPase SAR1 and related small G proteins R General function prediction only ; K07941|1|2e-101|367|aml:100473890|ADP-ribosylation factor 6 GO:0030838//positive regulation of actin filament polymerization;GO:0006915//apoptotic process;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0015031//protein transport;GO:0030866//cortical actin cytoskeleton organization;GO:0001889//liver development;GO:0055113//epiboly involved in gastrulation with mouth forming second;GO:0031529//ruffle organization;GO:0034143//regulation of toll-like receptor 4 signaling pathway;GO:0034394//protein localization to cell surface;GO:0035020//regulation of Rac protein signal transduction;GO:0060998//regulation of dendritic spine development;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0007155//cell adhesion;GO:0051489//regulation of filopodium assembly;GO:0006928//cellular component movement;GO:0006184//GTP catabolic process;GO:0090162//establishment of epithelial cell polarity GO:0005525//GTP binding;GO:0031996//thioesterase binding;GO:0003924//GTPase activity GO:0055037//recycling endosome;GO:0031527//filopodium membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0005938//cell cortex;GO:0001726//ruffle 60 sp|P14550|AK1A1_HUMAN Alcohol dehydrogenase [NADP(+)] OS=Homo sapiens GN=AKR1A1 PE=1 SV=3 >tr|V9HWI0|V9HWI0_HUMAN Epididymis secretory protein Li 6 OS=Homo sapiens GN=HEL-S-165mP PE=2 SV=1 43280 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY 106 14.2 - 5 5 3 3 0.837 0.976 1.049 3 4 3 - - - 0.954 0.107698654 sp|P14550|AK1A1_HUMAN 100 2.00E-179 gi|157834561|pdb|2ALR|A Chain A, Aldehyde Reductase 100 0 sp|P14550|AK1A1_HUMAN Alcohol dehydrogenase [NADP(+)] OS=Homo sapiens GN=AKR1A1 PE=1 SV=3 100 3.00E-82 Q5T621 Q5T621_HUMAN Alcohol dehydrogenase [NADP(+)] (Fragment) OS=Homo sapiens GN=AKR1A1 PE=2 SV=1 SPAC26F1.07 262 6.00E-70 COG0656 Aldo/keto reductases, related to diketogulonate reductase R General function prediction only ; K00002|1|0.0|634|hsa:10327|alcohol dehydrogenase (NADP+) [EC:1.1.1.2] GO:0042840//D-glucuronate catabolic process;GO:0046185//aldehyde catabolic process;GO:0006006//glucose metabolic process;GO:0019853//L-ascorbic acid biosynthetic process;GO:0055114//oxidation-reduction process GO:0009055//electron carrier activity;GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0047939//L-glucuronate reductase activity GO:0016324//apical plasma membrane;GO:0005829//cytosol 61 sp|P00338|LDHA_HUMAN L-lactate dehydrogenase A chain OS=Homo sapiens GN=LDHA PE=1 SV=2 >tr|V9HWB9|V9HWB9_HUMAN L-lactate dehydrogenase OS=Homo sapiens GN=HEL-S-133P PE=2 SV=1 45772 MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF 2616 24.7 - 152 149 8 7 0.492 0.348 0.407 93 95 91 - - * 0.415666667 0.072390147 sp|P00338|LDHA_HUMAN 100 0 gi|5031857|ref|NP_005557.1| L-lactate dehydrogenase A chain isoform 1 [Homo sapiens] >gi|126047|sp|P00338.2|LDHA_HUMAN RecName: Full=L-lactate dehydrogenase A chain; Short=LDH-A; AltName: Full=Cell proliferation-inducing gene 19 protein; AltName: Full=LDH muscle subunit; Short=LDH-M; AltName: Full=Renal carcinoma antigen NY-REN-59 >gi|780261|emb|CAA26879.1| lactate dehydrogenase-A [Homo sapiens] >gi|41350405|gb|AAS00490.1| proliferation-inducing gene 19 protein [Homo sapiens] >gi|45501322|gb|AAH67223.1| Lactate dehydrogenase A [Homo sapiens] >gi|48145667|emb|CAG33056.1| LDHA [Homo sapiens] >gi|49456389|emb|CAG46515.1| LDHA [Homo sapiens] >gi|119588801|gb|EAW68395.1| lactate dehydrogenase A, isoform CRA_a [Homo sapiens] >gi|119588802|gb|EAW68396.1| lactate dehydrogenase A, isoform CRA_a [Homo sapiens] 100 0 sp|P00338|LDHA_HUMAN L-lactate dehydrogenase A chain OS=Homo sapiens GN=LDHA PE=1 SV=2 99.7 0 G1S7U7 G1S7U7_NOMLE L-lactate dehydrogenase OS=Nomascus leucogenys GN=LDHA PE=3 SV=1 CAC0267 276 3.00E-74 COG0039 Malate/lactate dehydrogenases C Energy production and conversion ; K00016|1|0.0|649|ptr:451063|L-lactate dehydrogenase [EC:1.1.1.27] GO:0031668//cellular response to extracellular stimulus;GO:0044262//cellular carbohydrate metabolic process;GO:0006090//pyruvate metabolic process;GO:0006096//glycolysis;GO:0055114//oxidation-reduction process GO:0004459//L-lactate dehydrogenase activity;GO:0000166//nucleotide binding GO:0005829//cytosol;GO:0005739//mitochondrion 62 tr|A0A024R571|A0A024R571_HUMAN EH domain-containing protein 1 OS=Homo sapiens GN=EHD1 PE=1 SV=1 75634 MEQPGTAASPVSGSMFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE 100 3.8 9 7 7 2 2 1.41 0.983 1.033 4 4 4 - - - 1.142 0.233437358 tr|A0A024R571|A0A024R571_HUMAN 100 7.00E-74 gi|444724481|gb|ELW65084.1| EH domain-containing protein 1 [Tupaia chinensis] 100 0 sp|Q9H4M9|EHD1_HUMAN EH domain-containing protein 1 OS=Homo sapiens GN=EHD1 PE=1 SV=2 100 0 H2Q409 H2Q409_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000110047 PE=4 SV=1 DR1235 52.8 2.00E-06 COG0699 Predicted GTPases (dynamin-related) R General function prediction only ; K12483|1|0.0|1058|mcc:722036|EH domain-containing protein 1 GO:0010886//positive regulation of cholesterol storage;GO:0032456//endocytic recycling;GO:0034383//low-density lipoprotein particle clearance;GO:0006184//GTP catabolic process;GO:0006886//intracellular protein transport;GO:0007596//blood coagulation;GO:0006897//endocytosis;GO:0051260//protein homooligomerization;GO:0042632//cholesterol homeostasis GO:0005515//protein binding;GO:0005525//GTP binding;GO:0005509//calcium ion binding;GO:0003924//GTPase activity;GO:0005524//ATP binding GO:0055038//recycling endosome membrane;GO:0031095//platelet dense tubular network membrane;GO:0030139//endocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0005811//lipid particle;GO:0005886//plasma membrane;GO:0031901//early endosome membrane 63 sp|Q8NHP8|PLBL2_HUMAN Putative phospholipase B-like 2 OS=Homo sapiens GN=PLBD2 PE=1 SV=2 72579 MVGQMYCYPGSHLARALTRALALALVLALLVGPFLSGLAGAIPAPGGRWARDGQVPPASRSRSVLLDVSAGQLLMVDGRHPDAVAWANLTNAIRETGWAFLELGTSGQYNDSLQAYAAGVVEAAVSEELIYMHWMNTVVNYCGPFEYEVGYCERLKSFLEANLEWMQEEMESNPDSPYWHQVRLTLLQLKGLEDSYEGRVSFPAGKFTIKPLGFLLLQLSGDLEDLELALNKTKIKPSLGSGSCSALIKLLPGQSDLLVAHNTWNNYQHMLRVIKKYWLQFREGPWGDYPLVPGNKLVFSSYPGTIFSCDDFYILGSGLVTLETTIGNKNPALWKYVRPRGCVLEWVRNIVANRLASDGATWADIFKRFNSGTYNNQWMIVDYKAFIPGGPSPGSRVLTILEQIPGMVVVADKTSELYQKTYWASYNIPSFETVFNASGLQALVAQYGDWFSYDGSPRAQIFRRNQSLVQDMDSMVRLMRYNDFLHDPLSLCKACNPQPNGENAISARSDLNPANGSYPFQALRQRSHGGIDVKVTSMSLARILSLLAASGPTWDQVPPFQWSTSPFSGLLHMGQPDLWKFAPVKVSWD 510 15.3 - 35 35 9 9 1.609 1.003 1.622 20 20 19 * - * 1.411333333 0.353686773 sp|Q8NHP8|PLBL2_HUMAN 100 0 gi|229093316|ref|NP_775813.2| putative phospholipase B-like 2 isoform 1 precursor [Homo sapiens] >gi|224471847|sp|Q8NHP8.2|PLBL2_HUMAN RecName: Full=Putative phospholipase B-like 2; AltName: Full=76 kDa protein; Short=p76; AltName: Full=LAMA-like protein 2; AltName: Full=Lamina ancestor homolog 2; AltName: Full=Phospholipase B domain-containing protein 2; Contains: RecName: Full=Putative phospholipase B-like 2 32 kDa form; Contains: RecName: Full=Putative phospholipase B-like 2 45 kDa form; Flags: Precursor 100 0 sp|Q8NHP8|PLBL2_HUMAN Putative phospholipase B-like 2 OS=Homo sapiens GN=PLBD2 PE=1 SV=2 98.88 0 H2Q6Y0 H2Q6Y0_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000151176 PE=4 SV=1 - - - - - - - - GO:0016042//lipid catabolic process GO:0016787//hydrolase activity GO:0043202//lysosomal lumen 64 sp|Q9NP84|TNR12_HUMAN Tumor necrosis factor receptor superfamily member 12A OS=Homo sapiens GN=TNFRSF12A PE=1 SV=1 15271 MARGSLRRLLRLLVLGLWLALLRSVAGEQAPGTAPCSRGSSWSADLDKCMDCASCRARPHSDFCLGCAAAPPAPFRLLWPILGGALSLTFVLGLLSGFLVWRRCRRREKFTTPIEETGGEGCPAVALIQ 50 23.3 - 3 3 2 2 0.53 1.052 0.665 2 2 2 * - - 0.749 0.270948335 sp|Q9NP84|TNR12_HUMAN 100 2.00E-53 gi|332240124|ref|XP_003269240.1| PREDICTED: tumor necrosis factor receptor superfamily member 12A isoform 1 [Nomascus leucogenys] >gi|441659212|ref|XP_004091334.1| PREDICTED: tumor necrosis factor receptor superfamily member 12A isoform 2 [Nomascus leucogenys] >gi|441659215|ref|XP_004091335.1| PREDICTED: tumor necrosis factor receptor superfamily member 12A isoform 3 [Nomascus leucogenys] 100 3.00E-54 sp|Q9NP84|TNR12_HUMAN Tumor necrosis factor receptor superfamily member 12A OS=Homo sapiens GN=TNFRSF12A PE=1 SV=1 100 1.00E-52 F7DBW1 F7DBW1_MACMU Uncharacterized protein OS=Macaca mulatta GN=TNFRSF12A PE=4 SV=1 - - - - - - - K05149|1|3e-54|209|pon:100431323|tumor necrosis factor receptor superfamily member 12A GO:0001525//angiogenesis;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0045773//positive regulation of axon extension;GO:0006917//induction of apoptosis;GO:0006931//substrate-dependent cell migration, cell attachment to substrate GO:0005515//protein binding GO:0016021//integral to membrane;GO:0009986//cell surface;GO:0001726//ruffle;GO:0005886//plasma membrane 65 tr|Q5U0B9|Q5U0B9_HUMAN Stem cell growth factor; lymphocyte secreted C-type lectin OS=Homo sapiens GN=CLEC11A PE=2 SV=1 37494 MQAAWPLGALVVPQLLGFGHGARGAEREWEGGWGGAQEEEREREALMLKHLQEALGLPAGRGDENPAGTVEGKEDCEMEEDQGEEEEEEATPTPSSGPSPSPTPEDIVTYILGRLAGLDAGLHQLHVRLHALDTRVVELTQGLRQLRNAAGDTRDAVQALQEAQGRAEREHGRLEGCLKGLRLGHKCFLLSRDFEAQAAAQARCTARGGSLAQPADRQQMEALTRYLRAALAPYNWPVWLGVHDRRAEGLYLFENGQRVSFFAWHRSPRPELGAQPSASPHPLSPDQPNGGTLENCVAQASDDGSWWDHDCQRRLYYVCEFPF 414 22.6 1 19 19 6 6 1.421 1.23 1.288 15 14 15 - * * 1.313 0.097923439 tr|Q5U0B9|Q5U0B9_HUMAN 100 6.00E-140 gi|54696214|gb|AAV38479.1| stem cell growth factor; lymphocyte secreted C-type lectin [Homo sapiens] 99.38 9.00E-140 sp|Q9Y240|CLC11_HUMAN C-type lectin domain family 11 member A OS=Homo sapiens GN=CLEC11A PE=1 SV=1 100 1.00E-23 H9FBT5 H9FBT5_MACMU C-type lectin domain family 11 member A (Fragment) OS=Macaca mulatta GN=CLEC11A PE=2 SV=1 - - - - - - - K12589|1|2e-16|87.0|aml:100484320|exosome complex component RRP42!K10065|5|8e-08|58.2|mdo:100031842|collectin sub-family member 10 GO:0008284//positive regulation of cell proliferation GO:0008083//growth factor activity;GO:0030246//carbohydrate binding GO:0005813//centrosome;GO:0005576//extracellular region 66 tr|B4DLT1|B4DLT1_HUMAN cDNA FLJ59716, highly similar to Vacuolar protein sorting 26A OS=Homo sapiens PE=2 SV=1 44324 MTENPFQERYSVEDLSTFGMCLCMVRYVYDAFYKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQPIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPESQASAEQPEM 98 4.8 2 6 6 2 2 1.218 0.867 0.682 3 3 3 - - - 0.922333333 0.272250497 tr|B4DLT1|B4DLT1_HUMAN 100 0 gi|194386158|dbj|BAG59643.1| unnamed protein product [Homo sapiens] 99.64 3.00E-160 sp|Q0VD53|VP26A_BOVIN Vacuolar protein sorting-associated protein 26A OS=Bos taurus GN=VPS26A PE=2 SV=1 100 0 B4DLT1 B4DLT1_HUMAN cDNA FLJ59716, highly similar to Vacuolar protein sorting 26A OS=Homo sapiens PE=2 SV=1 - - - - - - - - GO:0042147//retrograde transport, endosome to Golgi;GO:0007034//vacuolar transport;GO:0015031//protein transport GO:0005515//protein binding;GO:0008565//protein transporter activity GO:0030904//retromer complex;GO:0031982//vesicle;GO:0005829//cytosol;GO:0010008//endosome membrane 67 tr|B7Z1F8|B7Z1F8_HUMAN cDNA FLJ53025, highly similar to Complement C4-B OS=Homo sapiens PE=2 SV=1 36015 MCPEDSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRGHVFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQEVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIESPGG 1344 54.4 - 71 6 14 2 0.815 2.731 1.116 4 3 2 - - - 1.554 1.030362558 tr|B7Z1F8|B7Z1F8_HUMAN 100 7.00E-158 gi|221039462|dbj|BAH11494.1| unnamed protein product [Homo sapiens] 99.25 2.00E-154 sp|P0C0L5|CO4B_HUMAN Complement C4-B OS=Homo sapiens GN=C4B PE=1 SV=1 100 2.00E-157 B7Z1F8 B7Z1F8_HUMAN cDNA FLJ53025, highly similar to Complement C4-B OS=Homo sapiens PE=2 SV=1 - - - - - - - K03989|1|2e-154|545|hsa:720|complement component 4 GO:0006958//complement activation, classical pathway;GO:0045087//innate immune response;GO:0030449//regulation of complement activation GO:0004866//endopeptidase inhibitor activity GO:0005615//extracellular space;GO:0005886//plasma membrane 68 tr|A0A024R394|A0A024R394_HUMAN Cysteine and histidine-rich domain (CHORD)-containing 1, isoform CRA_c OS=Homo sapiens GN=CHORDC1 PE=4 SV=1 50476 MALLCYNRGCGQRFDPETNSDDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGRHNSEKPPEPVKPEVKTTEKKELCELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLKLSSGNEENKKEEDNDEIKIGTSCKNGGCSKTYQGLESLEEVCVYHSGVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTKGKHMWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSRVEANSTLLNVHIVFEGEKEFDQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASLELPAAKKQEKQKDDTTD 49 6.9 1 3 3 2 2 1.525 0.716 0.78 2 2 2 - - - 1.007 0.449741037 tr|A0A024R394|A0A024R394_HUMAN 100 7.00E-34 gi|178847390|pdb|2YRT|A Chain A, Solution Structure Of The Chord Domain Of Human Chord- Containing Protein 1 100 6.00E-166 sp|Q9UHD1|CHRD1_HUMAN Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens GN=CHORDC1 PE=1 SV=2 100 5.00E-44 E9PSD5 E9PSD5_HUMAN Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens GN=CHORDC1 PE=4 SV=1 - - - - - - - K12795|1|8e-06|51.6|xtr:548910|suppressor of G2 allele of SKP1 GO:2000299//negative regulation of Rho-dependent protein serine/threonine kinase activity;GO:0080134//regulation of response to stress;GO:0010824//regulation of centrosome duplication;GO:0061077//chaperone-mediated protein folding GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0051879//Hsp90 protein binding - 69 sp|Q9BTY2|FUCO2_HUMAN Plasma alpha-L-fucosidase OS=Homo sapiens GN=FUCA2 PE=1 SV=2 62284 MRPQELPRLAFPLLLLLLLLLPPPPCPAHSATRFDPTWESLDARQLPAWFDQAKFGIFIHWGVFSVPSFGSEWFWWYWQKEKIPKYVEFMKDNYPPSFKYEDFGPLFTAKFFNANQWADIFQASGAKYIVLTSKHHEGFTLWGSEYSWNWNAIDEGPKRDIVKELEVAIRNRTDLRFGLYYSLFEWFHPLFLEDESSSFHKRQFPVSKTLPELYELVNNYQPEVLWSDGDGGAPDQYWNSTGFLAWLYNESPVRGTVVTNDRWGAGSICKHGGFYTCSDRYNPGHLLPHKWENCMTIDKLSWGYRREAGISDYLTIEELVKQLVETVSCGGNLLMNIGPTLDGTISVVFEERLRQMGSWLKVNGEAIYETHTWRSQNDTVTPDVWYTSKPKEKLVYAIFLKWPTSGQLFLGHPKAILGATEVKLLGHGQPLNWISLEQNGIMVELPQLTIHQMPCKWGWALALTNVI 168 10.1 - 13 13 4 4 0.998 0.724 1.02 8 8 8 - - - 0.914 0.164912098 sp|Q9BTY2|FUCO2_HUMAN 100 0 gi|114609589|ref|XP_518777.2| PREDICTED: plasma alpha-L-fucosidase [Pan troglodytes] 100 0 sp|Q9BTY2|FUCO2_HUMAN Plasma alpha-L-fucosidase OS=Homo sapiens GN=FUCA2 PE=1 SV=2 100 0 H2QTV0 H2QTV0_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000001036 PE=4 SV=1 TM0306 235 1.00E-61 COG3669 Alpha-L-fucosidase G Carbohydrate transport and metabolism ; K01206|1|0.0|914|hsa:2519|alpha-L-fucosidase [EC:3.2.1.51] GO:0006004//fucose metabolic process GO:0004560//alpha-L-fucosidase activity;GO:0043169//cation binding GO:0005576//extracellular region 70 tr|C9JPM4|C9JPM4_HUMAN ADP-ribosylation factor 4 (Fragment) OS=Homo sapiens GN=ARF4 PE=1 SV=1 17643 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAVLLLFANK 84 16.5 1 6 4 2 1 1.427 1.077 1.254 2 2 2 - - - 1.252666667 0.175003809 tr|C9JPM4|C9JPM4_HUMAN 100 2.00E-68 gi|4502205|ref|NP_001651.1| ADP-ribosylation factor 4 [Homo sapiens] >gi|197101829|ref|NP_001125296.1| ADP-ribosylation factor 4 [Pongo abelii] >gi|307133710|ref|NP_001182511.1| ADP-ribosylation factor 4 [Macaca mulatta] >gi|114123|sp|P18085.3|ARF4_HUMAN RecName: Full=ADP-ribosylation factor 4 >gi|68565025|sp|Q5RCF1.3|ARF4_PONAB RecName: Full=ADP-ribosylation factor 4 >gi|66361349|pdb|1Z6X|A Chain A, Structure Of Human Adp-Ribosylation Factor 4 >gi|66361350|pdb|1Z6X|B Chain B, Structure Of Human Adp-Ribosylation Factor 4 >gi|20147659|gb|AAM12597.1|AF493883_1 ADP-ribosylation factor protein 4 [Homo sapiens] >gi|178985|gb|AAA53081.1| ADP-ribosylation factor 4 [Homo sapiens] >gi|5880488|gb|AAD54674.1| ADP-ribosylation factor 4 [Homo sapiens] >gi|13097192|gb|AAH03364.1| ADP-ribosylation factor 4 [Homo sapiens] >gi|14250597|gb|AAH08753.1| ADP-ribosylation factor 4 [Homo sapiens] >gi|16740934|gb|AAH16325.1| ADP-ribosylation factor 4 [Homo sapiens] >gi|18605551|gb|AAH22866.1| ADP-ribosylation factor 4 [Homo sapiens] 100 2.00E-69 sp|Q5RCF1|ARF4_PONAB ADP-ribosylation factor 4 OS=Pongo abelii GN=ARF4 PE=2 SV=3 100 1.00E-67 C9JPM4 C9JPM4_HUMAN ADP-ribosylation factor 4 (Fragment) OS=Homo sapiens GN=ARF4 PE=3 SV=1 YDL137w 205 2.00E-53 COG1100 GTPase SAR1 and related small G proteins R General function prediction only ; K07939|1|2e-69|260|mcc:703432|ADP-ribosylation factor 4 GO:0016192//vesicle-mediated transport;GO:0007264//small GTPase mediated signal transduction;GO:0007420//brain development;GO:0006184//GTP catabolic process;GO:0048678//response to axon injury;GO:0015031//protein transport;GO:0007173//epidermal growth factor receptor signaling pathway GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding GO:0048471//perinuclear region of cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane 71 tr|B2R5W2|B2R5W2_HUMAN Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens GN=HNRNPC PE=2 SV=1 41112 MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSSFDLDYDFQRDYYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQRGSSKSGKLKGDDLQAIKKELTQIKQKVDSLLENLEKIEKEQSKQAVEMKNDKSEEEQSSSSVKKDETNVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEEGEDDRDSANGG 114 14.5 8 8 8 4 4 0.993 1.188 1.22 4 4 4 - - - 1.133666667 0.122867137 tr|B2R5W2|B2R5W2_HUMAN 100 2.00E-103 gi|189065420|dbj|BAG35259.1| unnamed protein product [Homo sapiens] 94.94 6.00E-101 sp|P07910|HNRPC_HUMAN Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens GN=HNRNPC PE=1 SV=4 100 8.00E-56 B4DSU6 B4DSU6_HUMAN Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens GN=HNRNPC PE=2 SV=1 - - - - - - - K12884|1|2e-104|379|ptr:465214|heterogeneous nuclear ribonucleoprotein C1/C2 GO:0000398//mRNA splicing, via spliceosome GO:0042802//identical protein binding;GO:0003729//mRNA binding;GO:0000166//nucleotide binding GO:0005654//nucleoplasm;GO:0045120//pronucleus;GO:0071013//catalytic step 2 spliceosome 72 tr|B4DVZ8|B4DVZ8_HUMAN Leukotriene A(4) hydrolase OS=Homo sapiens PE=2 SV=1 76414 MPEIVDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD 145 14.1 1 13 13 7 7 0.907 1.13 0.748 3 3 3 - - - 0.928333333 0.191891462 tr|B4DVZ8|B4DVZ8_HUMAN 100 0 gi|194376202|dbj|BAG62860.1| unnamed protein product [Homo sapiens] 99.64 0 sp|P09960|LKHA4_HUMAN Leukotriene A-4 hydrolase OS=Homo sapiens GN=LTA4H PE=1 SV=2 100 0 B4DVZ8 B4DVZ8_HUMAN cDNA FLJ52432, highly similar to Leukotriene A-4 hydrolase (EC 3.3.2.6) OS=Homo sapiens PE=2 SV=1 SPCC1322.05c 461 2.00E-129 COG0308 Aminopeptidase N E Amino acid transport and metabolism ; K01254|1|0.0|1162|hsa:4048|leukotriene-A4 hydrolase [EC:3.3.2.6] GO:0019370//leukotriene biosynthetic process;GO:0006954//inflammatory response;GO:0043171//peptide catabolic process;GO:0006508//proteolysis;GO:0043434//response to peptide hormone stimulus;GO:0060509//Type I pneumocyte differentiation;GO:0010043//response to zinc ion GO:0008270//zinc ion binding;GO:0004177//aminopeptidase activity;GO:0008237//metallopeptidase activity;GO:0004463//leukotriene-A4 hydrolase activity;GO:0004301//epoxide hydrolase activity GO:0005829//cytosol;GO:0005730//nucleolus 73 tr|A1YYW4|A1YYW4_HUMAN Superoxide dismutase 1 (Fragment) OS=Homo sapiens GN=SOD1 PE=2 SV=1 5330 MATKAVCVLKGDGPVQGIINFEQKESNGPDEGVGKH 604 38.9 2 15 15 1 1 0.837 0.781 0.741 14 15 15 * * * 0.786333333 0.04822171 tr|A1YYW4|A1YYW4_HUMAN 100 3.00E-08 gi|34810328|pdb|1P1V|A Chain A, Crystal Structure Of Fals-Associated Human Copper-Zinc Superoxide Dismutase (Cuznsod) Mutant D125h To 1.4a >gi|34810329|pdb|1P1V|B Chain B, Crystal Structure Of Fals-Associated Human Copper-Zinc Superoxide Dismutase (Cuznsod) Mutant D125h To 1.4a >gi|34810330|pdb|1P1V|C Chain C, Crystal Structure Of Fals-Associated Human Copper-Zinc Superoxide Dismutase (Cuznsod) Mutant D125h To 1.4a 100 7.00E-10 sp|P00441|SODC_HUMAN Superoxide dismutase [Cu-Zn] OS=Homo sapiens GN=SOD1 PE=1 SV=2 100 3.00E-08 G3RHP5 G3RHP5_GORGO Superoxide dismutase [Cu-Zn] OS=Gorilla gorilla gorilla GN=SOD1 PE=3 SV=1 - - - - - - - K04565|1|6e-10|62.8|ptr:449637|Cu/Zn superoxide dismutase [EC:1.15.1.1] - - 74 sp|P07900|HS90A_HUMAN Heat shock protein HSP 90-alpha OS=Homo sapiens GN=HSP90AA1 PE=1 SV=5 >tr|K9JA46|K9JA46_HUMAN Epididymis luminal secretory protein 52 OS=Homo sapiens GN=EL52 PE=2 SV=1 109646 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 859 16.3 - 35 22 10 7 1.434 1.169 1.829 18 18 18 * - * 1.477333333 0.332126984 sp|P07900|HS90A_HUMAN 100 0 gi|32488|emb|CAA33259.1| unnamed protein product [Homo sapiens] 100 5.00E-130 sp|O02705|HS90A_PIG Heat shock protein HSP 90-alpha OS=Sus scrofa GN=HSP90AA1 PE=2 SV=3 100 7.00E-20 Q3TJU7 Q3TJU7_MOUSE Putative uncharacterized protein (Fragment) OS=Mus musculus GN=Hsp90aa1 PE=2 SV=1 SPAC926.04c 856 0 COG0326 Molecular chaperone, HSP90 family O Posttranslational modification, protein turnover, chaperones ; K04079|1|0.0|866|mcc:708431|molecular chaperone HtpG GO:0007411//axon guidance;GO:0051131//chaperone-mediated protein complex assembly;GO:0045040//protein import into mitochondrial outer membrane;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0050999//regulation of nitric-oxide synthase activity;GO:0007165//signal transduction;GO:0042026//protein refolding;GO:0006200//ATP catabolic process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006986//response to unfolded protein GO:0030911//TPR domain binding;GO:0030235//nitric-oxide synthase regulator activity;GO:0051082//unfolded protein binding;GO:0016887//ATPase activity;GO:0042803//protein homodimerization activity;GO:0005524//ATP binding GO:0042470//melanosome;GO:0005829//cytosol;GO:0005886//plasma membrane 75 tr|V9HW62|V9HW62_HUMAN Lactoylglutathione lyase OS=Homo sapiens GN=HEL-S-74 PE=2 SV=1 26714 MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDATQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM 373 31 1 12 12 4 4 0.862 0.662 0.85 10 11 10 - * - 0.791333333 0.112166543 tr|V9HW62|V9HW62_HUMAN 100 1.00E-105 gi|5020074|gb|AAD38008.1|AF146651_1 glyoxalase-I [Homo sapiens] >gi|183258|gb|AAA52565.1| glyoxaslase I [Homo sapiens] >gi|219664|dbj|BAA02572.1| lactoyl glutathione lyase [Homo sapiens] >gi|16198506|gb|AAH15934.1| Glyoxalase I [Homo sapiens] 99.46 7.00E-106 sp|Q04760|LGUL_HUMAN Lactoylglutathione lyase OS=Homo sapiens GN=GLO1 PE=1 SV=4 98.91 5.00E-104 H2QSX9 H2QSX9_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000124767 PE=4 SV=1 XF1399 172 3.00E-43 COG0346 Lactoylglutathione lyase and related lyases E Amino acid transport and metabolism ; K01759|1|7e-106|382|hsa:2739|lactoylglutathione lyase [EC:4.4.1.5] GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0005975//carbohydrate metabolic process;GO:0006749//glutathione metabolic process;GO:0009438//methylglyoxal metabolic process GO:0046872//metal ion binding;GO:0004462//lactoylglutathione lyase activity GO:0005737//cytoplasm 76 sp|P10599|THIO_HUMAN Thioredoxin OS=Homo sapiens GN=TXN PE=1 SV=3 >tr|H9ZYJ2|H9ZYJ2_HUMAN Thioredoxin OS=Homo sapiens GN=TXN PE=2 SV=1 15970 MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV 637 31.4 - 26 26 3 3 0.791 0.743 0.84 23 24 23 * * * 0.791333333 0.048500859 sp|P10599|THIO_HUMAN 100 3.00E-50 gi|441592862|ref|XP_003260517.2| PREDICTED: thioredoxin isoform 1 [Nomascus leucogenys] 100 1.00E-55 sp|P10599|THIO_HUMAN Thioredoxin OS=Homo sapiens GN=TXN PE=1 SV=3 100 4.00E-54 H2QXP0 H2QXP0_PANTR Thioredoxin OS=Pan troglodytes GN=ENSG00000136810 PE=3 SV=1 SPAC7D4.07c 101 3.00E-22 COG0526 Thiol-disulfide isomerase and thioredoxins OC Posttranslational modification, protein turnover, chaperones ; Energy production and conversion ; K03671|1|4e-58|222|ptr:740248|thioredoxin 1 GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0033158//regulation of protein import into nucleus, translocation;GO:0007267//cell-cell signaling;GO:0006928//cellular component movement;GO:0008283//cell proliferation;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0022900//electron transport chain;GO:0045454//cell redox homeostasis;GO:0015949//nucleobase-containing small molecule interconversion;GO:0006662//glycerol ether metabolic process;GO:0009314//response to radiation;GO:0043388//positive regulation of DNA binding;GO:0045087//innate immune response;GO:0046826//negative regulation of protein export from nucleus GO:0015035//protein disulfide oxidoreductase activity;GO:0005515//protein binding;GO:0009055//electron carrier activity;GO:0015037//peptide disulfide oxidoreductase activity GO:0005654//nucleoplasm;GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005739//mitochondrion 77 tr|B3KNX0|B3KNX0_HUMAN cDNA FLJ30621 fis, clone CTONG2001681, highly similar to Complement C1s subcomponent (EC 3.4.21.42) OS=Homo sapiens PE=2 SV=1 89744 MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFPNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKNYVDWIMKTMQENSTPRED 1638 29.5 2 69 69 15 15 3.141 2.356 3.071 48 51 47 * - - 2.856 0.434424907 tr|B3KNX0|B3KNX0_HUMAN 100 0 gi|193786199|dbj|BAG51482.1| unnamed protein product [Homo sapiens] 99.85 0 sp|P09871|C1S_HUMAN Complement C1s subcomponent OS=Homo sapiens GN=C1S PE=1 SV=1 100 7.00E-88 F5H7T4 F5H7T4_HUMAN Complement C1s subcomponent heavy chain (Fragment) OS=Homo sapiens GN=C1S PE=4 SV=1 mlr3307 77.8 6.00E-14 COG5640 Secreted trypsin-like serine protease O Posttranslational modification, protein turnover, chaperones ; K01331|1|0.0|1390|hsa:716|complement component 1, s subcomponent [EC:3.4.21.42] GO:0045087//innate immune response;GO:0006958//complement activation, classical pathway;GO:0006508//proteolysis;GO:0010001//glial cell differentiation;GO:0051591//response to cAMP GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding GO:0005576//extracellular region 78 tr|Q8TCF0|Q8TCF0_HUMAN LBP protein OS=Homo sapiens GN=LBP PE=2 SV=1 60068 MGALARALPSILLALLLTSTPEALGANPGLVARITDKGLQYAAQEGLLALQSELLRITLPDFTGDLRIPHVGRGRYEFHSLNIHSCELLHSALRPVPGQGLSLSISDSSIRVQGRWKVRKSFFKLQGSFDVSVKGISISVNLLLGSESSGRPTVTASSCSSDIADVEVDMSGDLGWLLNLFHNQIESKFQKVLESRICEMIQKSVSSDLQPYLQTLPVTTEIDSFADIDYSLVEAPRATAQMLEVMFKGEIFHRNHRSPVTLLAAVMSLPEEHNKMVYFAISDYVFNTASLVYHEEGYLNFSITDDMIPPDSNIRLTTKSFRPFVPRLARLYPNMNLELQGSVPSAPLLNFSPGNLSVDPYMEIDAFVLLPSSSKEPVFRLSVATNVSATLTFNTSKITGFLKPGKVKVELKESKVGLFNAELLEALLNYYILNTFYPKFNDKLAEGFPLPLLKRVQLYDLGLQIHKDFPSRRDHPP 111 4.6 1 5 5 2 2 1.034 2.535 0.935 5 3 2 - * - 1.501333333 0.896549125 tr|Q8TCF0|Q8TCF0_HUMAN 100 0 gi|119596439|gb|EAW76033.1| lipopolysaccharide binding protein, isoform CRA_a [Homo sapiens] 100 0 sp|P18428|LBP_HUMAN Lipopolysaccharide-binding protein OS=Homo sapiens GN=LBP PE=1 SV=3 100 0 Q8TCF0 Q8TCF0_HUMAN LBP protein OS=Homo sapiens GN=LBP PE=2 SV=1 - - - - - - - K05399|1|0.0|851|hsa:3929|lipopolysaccharide-binding protein GO:0032722//positive regulation of chemokine production;GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0032760//positive regulation of tumor necrosis factor production;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0008063//Toll signaling pathway;GO:0050829//defense response to Gram-negative bacterium;GO:0032490//detection of molecule of bacterial origin;GO:0015920//lipopolysaccharide transport;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0060265//positive regulation of respiratory burst involved in inflammatory response;GO:0071223//cellular response to lipoteichoic acid;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0044130//negative regulation of growth of symbiont in host;GO:0043032//positive regulation of macrophage activation;GO:0002281//macrophage activation involved in immune response;GO:0008228//opsonization;GO:0006953//acute-phase response;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032757//positive regulation of interleukin-8 production;GO:0050830//defense response to Gram-positive bacterium;GO:0032755//positive regulation of interleukin-6 production;GO:0006968//cellular defense response GO:0005102//receptor binding;GO:0070891//lipoteichoic acid binding;GO:0051637//Gram-positive bacterial cell surface binding;GO:0051636//Gram-negative bacterial cell surface binding;GO:0001530//lipopolysaccharide binding;GO:0008289//lipid binding GO:0005615//extracellular space 79 tr|B3KSI7|B3KSI7_HUMAN cDNA FLJ36374 fis, clone THYMU2008185, highly similar to Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) OS=Homo sapiens PE=2 SV=1 73935 MWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPTDYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKDKVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGDRIDAPSVKEHLLLDLGLEAEYRIQVHPYKPILSELKALCADLSPREKVWVSDKASYAVSETIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLVVPVKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDSLTDKECDWLNNYHLTCRDVIGKELQKQGRQEALEWLIRETQPISKQH 130 5.4 2 5 5 2 2 1 0.846 0.684 4 4 4 - - - 0.843333333 0.158016877 tr|B3KSI7|B3KSI7_HUMAN 100 0 gi|193787543|dbj|BAG52749.1| unnamed protein product [Homo sapiens] 99.82 0 sp|Q9NQW7|XPP1_HUMAN Xaa-Pro aminopeptidase 1 OS=Homo sapiens GN=XPNPEP1 PE=1 SV=3 100 0 B3KSI7 B3KSI7_HUMAN cDNA FLJ36374 fis, clone THYMU2008185, highly similar to Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) OS=Homo sapiens PE=2 SV=1 YLL029w 368 2.00E-101 COG0006 Xaa-Pro aminopeptidase E Amino acid transport and metabolism ; K01262|1|0.0|1147|pon:100457613|Xaa-Pro aminopeptidase [EC:3.4.11.9] GO:0006508//proteolysis;GO:0010815//bradykinin catabolic process GO:0070006//metalloaminopeptidase activity;GO:0030145//manganese ion binding;GO:0042803//protein homodimerization activity GO:0005829//cytosol 80 sp|P53621|COPA_HUMAN Coatomer subunit alpha OS=Homo sapiens GN=COPA PE=1 SV=2 165351 MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSLLIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFDPEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDTVGTEGWGEDAELQLDEDGFVEATEGLGDDALGKGQEEGGGWDVEEDLELPPELDISPGAAGGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQFGPYKQLFLQTYARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLSVETERKKLPKETLEQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDAYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICRVTTVTEIGKDVIGLRISPLQFR 126 5.6 - 7 7 5 5 1.089 0.866 0.801 2 2 2 - - - 0.918666667 0.151050764 sp|P53621|COPA_HUMAN 100 0 gi|148536853|ref|NP_004362.2| coatomer subunit alpha isoform 2 [Homo sapiens] >gi|205371746|sp|P53621.2|COPA_HUMAN RecName: Full=Coatomer subunit alpha; AltName: Full=Alpha-coat protein; Short=Alpha-COP; AltName: Full=HEP-COP; Short=HEPCOP; Contains: RecName: Full=Xenin; AltName: Full=Xenopsin-related peptide; Contains: RecName: Full=Proxenin >gi|119573108|gb|EAW52723.1| coatomer protein complex, subunit alpha, isoform CRA_a [Homo sapiens] 100 0 sp|P53621|COPA_HUMAN Coatomer subunit alpha OS=Homo sapiens GN=COPA PE=1 SV=2 99.67 0 H2N548 H2N548_PONAB Uncharacterized protein OS=Pongo abelii GN=COPA PE=4 SV=1 ECU01g1290 318 3.00E-86 COG2319 FOG: WD40 repeat R General function prediction only ; K05236|1|0.0|2521|hsa:1314|coatomer protein complex, subunit alpha (xenin) GO:0030157//pancreatic juice secretion;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0048205//COPI coating of Golgi vesicle;GO:0006886//intracellular protein transport GO:0005198//structural molecule activity;GO:0005179//hormone activity GO:0030126//COPI vesicle coat;GO:0005829//cytosol;GO:0005615//extracellular space 81 tr|G3V1V0|G3V1V0_HUMAN Myosin light polypeptide 6 OS=Homo sapiens GN=MYL6 PE=1 SV=1 21657 MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEGKRRCEGLQESCSHHNPPA 404 28 5 25 25 4 4 0.606 0.491 0.544 12 13 13 * * * 0.547 0.057558666 tr|G3V1V0|G3V1V0_HUMAN 100 6.00E-78 gi|431914011|gb|ELK15273.1| Myosin light polypeptide 6 [Pteropus alecto] 100 4.00E-79 sp|Q64119|MYL6_RAT Myosin light polypeptide 6 OS=Rattus norvegicus GN=Myl6 PE=1 SV=3 100 1.00E-77 H2NHN7 H2NHN7_PONAB Myosin light polypeptide 6 OS=Pongo abelii GN=MYL6 PE=4 SV=1 SPAC3A12.14 111 4.00E-25 COG5126 Ca2+-binding protein (EF-Hand superfamily) TZDR Signal transduction mechanisms ; Cytoskeleton ; Cell cycle control, cell division, chromosome partitioning ; General function prediction only ; K12751|1|2e-79|293|ssc:100625485|myosin light chain 6 GO:0007411//axon guidance;GO:0030049//muscle filament sliding;GO:0007519//skeletal muscle tissue development;GO:0008152//metabolic process GO:0008307//structural constituent of muscle;GO:0000146//microfilament motor activity;GO:0005509//calcium ion binding;GO:0030898//actin-dependent ATPase activity;GO:0005515//protein binding GO:0005829//cytosol;GO:0016461//unconventional myosin complex 82 sp|P05556|ITB1_HUMAN Integrin beta-1 OS=Homo sapiens GN=ITGB1 PE=1 SV=2 109308 MNLQPIFWIGLISSVCCVFAQTDENRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPRGSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLENNMYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSSEVILENGKLSEGVTISYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITSNKCPKKDSDSFKIRPLGFTEEVEVILQYICECECQSEGIPESPKCHEGNGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFCECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGICECGVCKCTDPKFQGQTCEMCQTCLGVCAEHKECVQCRAFNKGEKKDTCTQECSYFNITKVESRDKLPQPVQPDPVSHCKEKDVDDCWFYFTYSVNGNNEVMVHVVENPECPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK 69 5.8 - 8 8 4 4 0.647 0.584 0.544 2 2 2 - - - 0.591666667 0.05192623 sp|P05556|ITB1_HUMAN 100 0 gi|119606355|gb|EAW85949.1| integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12), isoform CRA_b [Homo sapiens] >gi|119606357|gb|EAW85951.1| integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12), isoform CRA_b [Homo sapiens] 100 0 sp|P05556|ITB1_HUMAN Integrin beta-1 OS=Homo sapiens GN=ITGB1 PE=1 SV=2 100 0 G3QTG8 G3QTG8_GORGO Integrin beta OS=Gorilla gorilla gorilla GN=ITGB1 PE=3 SV=1 - - - - - - - K05719|1|0.0|1571|ptr:450396|integrin beta 1 GO:0043065//positive regulation of apoptotic process;GO:0055007//cardiac muscle cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0001894//tissue homeostasis;GO:0001701//in utero embryonic development;GO:0008284//positive regulation of cell proliferation;GO:0071479//cellular response to ionizing radiation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0050776//regulation of immune response;GO:0007411//axon guidance;GO:0045807//positive regulation of endocytosis;GO:0001708//cell fate specification;GO:0034698//response to gonadotropin stimulus;GO:0007156//homophilic cell adhesion;GO:0007159//leukocyte cell-cell adhesion;GO:0051726//regulation of cell cycle;GO:0007596//blood coagulation;GO:0070830//tight junction assembly;GO:0043410//positive regulation of MAPK cascade;GO:0006874//cellular calcium ion homeostasis;GO:0060135//maternal process involved in female pregnancy;GO:0045214//sarcomere organization;GO:0010811//positive regulation of cell-substrate adhesion;GO:0050900//leukocyte migration;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0019048//virus-host interaction;GO:0008354//germ cell migration;GO:0014823//response to activity;GO:0071305//cellular response to vitamin D;GO:0032594//protein transport within lipid bilayer;GO:0045666//positive regulation of neuron differentiation;GO:0030183//B cell differentiation;GO:0030335//positive regulation of cell migration;GO:0071559//response to transforming growth factor beta stimulus;GO:0008285//negative regulation of cell proliferation;GO:0033631//cell-cell adhesion mediated by integrin;GO:0010976//positive regulation of neuron projection development;GO:0007229//integrin-mediated signaling pathway;GO:0007161//calcium-independent cell-matrix adhesion;GO:0006968//cellular defense response;GO:0042493//response to drug;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0031345//negative regulation of cell projection organization;GO:0071260//cellular response to mechanical stimulus GO:0004872//receptor activity;GO:0005178//integrin binding;GO:0002020//protease binding;GO:0001968//fibronectin binding;GO:0051393//alpha-actinin binding;GO:0042277//peptide binding;GO:0019904//protein domain specific binding;GO:0001948//glycoprotein binding;GO:0019901//protein kinase binding;GO:0046982//protein heterodimerization activity;GO:0005518//collagen binding;GO:0043236//laminin binding;GO:0003779//actin binding GO:0030056//hemidesmosome;GO:0005925//focal adhesion;GO:0031594//neuromuscular junction;GO:0045121//membrane raft;GO:0034667//alpha3-beta1 integrin complex;GO:0005604//basement membrane;GO:0042383//sarcolemma;GO:0001669//acrosomal vesicle;GO:0032154//cleavage furrow;GO:0009897//external side of plasma membrane;GO:0042470//melanosome;GO:0034678//alpha8-beta1 integrin complex;GO:0034679//alpha9-beta1 integrin complex;GO:0035748//myelin sheath abaxonal region;GO:0014704//intercalated disc;GO:0032587//ruffle membrane 83 tr|A0A024R7P5|A0A024R7P5_HUMAN Similar to Laminin receptor 1, isoform CRA_a OS=Homo sapiens GN=LOC388524 PE=3 SV=1 24852 MSGALDVLQIKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFWEPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWGGHA 84 16.1 3 7 7 4 4 0.684 0.536 0.862 4 3 4 * * - 0.694 0.163229899 tr|A0A024R7P5|A0A024R7P5_HUMAN 100 2.00E-114 gi|119605356|gb|EAW84950.1| similar to Laminin receptor 1, isoform CRA_a [Homo sapiens] >gi|119605357|gb|EAW84951.1| similar to Laminin receptor 1, isoform CRA_a [Homo sapiens] 98.97 2.00E-111 sp|P08865|RSSA_HUMAN 40S ribosomal protein SA OS=Homo sapiens GN=RPSA PE=1 SV=4 99.46 9.00E-104 G1TGI6 G1TGI6_RABIT Uncharacterized protein (Fragment) OS=Oryctolagus cuniculus PE=3 SV=1 SPBC685.06 261 6.00E-70 COG0052 Ribosomal protein S2 J Translation, ribosomal structure and biogenesis ; K02998|1|2e-111|401|mcc:693293|small subunit ribosomal protein SAe GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006415//translational termination;GO:0006413//translational initiation;GO:0000028//ribosomal small subunit assembly;GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0016337//cell-cell adhesion;GO:0006414//translational elongation;GO:0000461//endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0019083//viral transcription;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006407//rRNA export from nucleus GO:0043236//laminin binding;GO:0043022//ribosome binding;GO:0003735//structural constituent of ribosome GO:0005604//basement membrane;GO:0043025//neuronal cell body;GO:0030686//90S preribosome;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0022627//cytosolic small ribosomal subunit 84 sp|Q6YHK3|CD109_HUMAN CD109 antigen OS=Homo sapiens GN=CD109 PE=1 SV=2 187444 MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYFMELWL 1081 13.4 - 44 44 15 15 1.275 1.195 1.332 30 30 31 * - - 1.267333333 0.068821024 sp|Q6YHK3|CD109_HUMAN 100 0 gi|115529484|ref|NP_598000.2| CD109 antigen isoform 1 precursor [Homo sapiens] >gi|117949389|sp|Q6YHK3.2|CD109_HUMAN RecName: Full=CD109 antigen; AltName: Full=150 kDa TGF-beta-1-binding protein; AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; AltName: Full=Platelet-specific Gov antigen; AltName: Full=p180; AltName: Full=r150; AltName: CD_antigen=CD109; Flags: Precursor >gi|119569137|gb|EAW48752.1| CD109 antigen (Gov platelet alloantigens), isoform CRA_a [Homo sapiens] 100 0 sp|Q6YHK3|CD109_HUMAN CD109 antigen OS=Homo sapiens GN=CD109 PE=1 SV=2 99.03 0 H2QTA3 H2QTA3_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000156535 PE=4 SV=1 TM0984 75.5 8.00E-13 COG2373 Large extracellular alpha-helical protein R General function prediction only ; K06530|1|0.0|2865|ptr:462825|CD109 antigen - GO:0004867//serine-type endopeptidase inhibitor activity GO:0031225//anchored to membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane 85 tr|B4DHC3|B4DHC3_HUMAN cDNA FLJ61254, highly similar to Receptor-type tyrosine-protein phosphatase kappa (EC 3.1.3.48) OS=Homo sapiens PE=2 SV=1 109329 MDTTAAAALPAFVALLLLSPWPLLGSAQGQFSAGGCTFDDGPGACDYHQDLYDDFEWVHVSAQEPHYLPPEMPQGSYMIVDSSDHDPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLNPGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAGQNATFQCIATGRDAVHNKLWLQRRNGEDIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGSGVSNFAQLIVREPPRPIAPPQLLGVGPTYLLIQLNANSIIGDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLTRPGEGGTGLPGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFRGHNESKADCLDMDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDEDVPGPVPVKSLQGTSFENKIFLNWKEPLDPNGIITQYEISYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNISAPTLPDYEGVDASLNETATTITVLLRPAQAKGAPISAYQIVVEELHPHRTKREAGAMECYQVPVTYQNAMSGGAPYYFAAELPPGNLPEPAPFTVGDNRTYQGFWNPPLAPRKGYNIYFQAMSSVEKETKTQCVRIATKAAATEEPEVIPDPAKQTDRVVKIAGISAGILVFILLLLVVILIVKKRRSYYSYSYYLKLAKKRKDAMGNTRQEMTHMVNAMDRSYADQSTLHAEDPLSITFMDQHNFSPRLPNDPLVPTAVLVPITGRKNVYHGDNNSFFAISYL 210 7.3 5 10 10 4 4 1.082 1.218 1.179 9 9 8 - * - 1.159666667 0.070030946 tr|B4DHC3|B4DHC3_HUMAN 100 0 gi|194379066|dbj|BAG58084.1| unnamed protein product [Homo sapiens] 96.33 0 sp|Q15262|PTPRK_HUMAN Receptor-type tyrosine-protein phosphatase kappa OS=Homo sapiens GN=PTPRK PE=1 SV=2 100 0 B4DHC3 B4DHC3_HUMAN cDNA FLJ61254, highly similar to Receptor-type tyrosine-protein phosphatase kappa (EC 3.1.3.48) OS=Homo sapiens PE=2 SV=1 - - - - - - - K06776|1|0.0|1575|mmu:19272|protein tyrosine phosphatase, receptor type, K [EC:3.1.3.48] GO:0030336//negative regulation of cell migration;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0034614//cellular response to reactive oxygen species;GO:0048041//focal adhesion assembly;GO:0045786//negative regulation of cell cycle;GO:0031175//neuron projection development;GO:0045892//negative regulation of transcription, DNA-dependent;GO:0034394//protein localization to cell surface;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0034644//cellular response to UV;GO:0010839//negative regulation of keratinocyte proliferation GO:0045295//gamma-catenin binding;GO:0019901//protein kinase binding;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0008013//beta-catenin binding GO:0001750//photoreceptor outer segment;GO:0005911//cell-cell junction;GO:0031256//leading edge membrane;GO:0009986//cell surface;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0030424//axon;GO:0005912//adherens junction;GO:0005887//integral to plasma membrane 86 tr|B4DF70|B4DF70_HUMAN cDNA FLJ60461, highly similar to Peroxiredoxin-2 (EC 1.11.1.15) OS=Homo sapiens PE=2 SV=1 23555 MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLAVTRLSPTWMTARNISPNTIRLANG 330 31.1 1 25 17 6 5 0.709 0.567 0.687 7 6 7 - * * 0.654333333 0.076428616 tr|B4DF70|B4DF70_HUMAN 100 3.00E-79 gi|90076926|dbj|BAE88143.1| unnamed protein product [Macaca fascicularis] 100 1.00E-87 sp|P32119|PRDX2_HUMAN Peroxiredoxin-2 OS=Homo sapiens GN=PRDX2 PE=1 SV=5 100 3.00E-86 G3S156 G3S156_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=PRDX2 PE=4 SV=1 SPCC576.03c 228 5.00E-60 COG0450 Peroxiredoxin O Posttranslational modification, protein turnover, chaperones ; K03386|1|1e-87|322|mcc:716665|peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15] GO:0042744//hydrogen peroxide catabolic process;GO:0010310//regulation of hydrogen peroxide metabolic process;GO:0045581//negative regulation of T cell differentiation;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0019430//removal of superoxide radicals;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0048872//homeostasis of number of cells;GO:0048538//thymus development;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0002536//respiratory burst involved in inflammatory response;GO:0055114//oxidation-reduction process;GO:0030194//positive regulation of blood coagulation;GO:0043524//negative regulation of neuron apoptotic process;GO:0000187//activation of MAPK activity;GO:0042098//T cell proliferation GO:0008379//thioredoxin peroxidase activity GO:0005829//cytosol;GO:0005739//mitochondrion 87 tr|B7Z9B8|B7Z9B8_HUMAN cDNA FLJ56912, highly similar to Fibulin-2 OS=Homo sapiens PE=2 SV=1 142967 METSLSLESGHHGSYRRGDRPGLAWTMVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQQGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPNCIEAVVVADSCPQCGQVGCVHAGHKYAAGHTVHLPPCRACHCPDAGGELICYQLPGCHGNFSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQAGAVQAGAGGPPAALGGGSQPLSTIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTEDSEEEEEEEEEREEMAVTEQLAAGGHRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAPSLGKAALVPTQAVPGSPRDPVKPSPHNILSTSLPDAAWIPPTRGVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLLVPAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRDFALDVEMKLWRQGSVTTFLAKMHIFFTTFAL 2384 22.9 1 124 124 21 21 2.39 2.496 3.068 88 92 85 * - * 2.651333333 0.364715414 tr|B7Z9B8|B7Z9B8_HUMAN 100 4.00E-126 gi|302313177|gb|ADL14513.1| truncated fibulin 2 [Homo sapiens] 99.91 0 sp|P98095|FBLN2_HUMAN Fibulin-2 OS=Homo sapiens GN=FBLN2 PE=1 SV=2 100 4.00E-69 C9JQS6 C9JQS6_HUMAN Fibulin-2 (Fragment) OS=Homo sapiens GN=FBLN2 PE=4 SV=1 - - - - - - - K08023|1|3e-59|231|xtr:100488719|latent transforming growth factor beta binding protein GO:0010811//positive regulation of cell-substrate adhesion GO:0005201//extracellular matrix structural constituent;GO:0050840//extracellular matrix binding;GO:0005509//calcium ion binding GO:0005578//proteinaceous extracellular matrix 88 tr|C9JMK5|C9JMK5_HUMAN Phosphoinositide-3-kinase-interacting protein 1 (Fragment) OS=Homo sapiens GN=PIK3IP1 PE=4 SV=3 18027 MLLAWVQAFLVSNMLLAEAYGSGGCFWDNGHLYREDQTSPAPGLRCLNWLDAQSGLASAPVSGAGNHSYCRNPDEDPRGPWCYVSGEAGVPEKRPCEDLRCPGQVQLWNSLRAVPDESCFPPHLQRPPPRPCQPSRQKSRKRLKG 91 10.3 1 3 3 1 1 1.431 1.148 2.214 3 3 3 - - - 1.597666667 0.55219773 tr|C9JMK5|C9JMK5_HUMAN 100 4.00E-56 gi|209571507|ref|NP_001129383.1| phosphoinositide-3-kinase-interacting protein 1 isoform 2 precursor [Homo sapiens] >gi|119580366|gb|EAW59962.1| HGFL gene, isoform CRA_c [Homo sapiens] 100 5.00E-58 sp|Q96FE7|P3IP1_HUMAN Phosphoinositide-3-kinase-interacting protein 1 OS=Homo sapiens GN=PIK3IP1 PE=1 SV=2 100 4.00E-67 C9JMK5 C9JMK5_HUMAN Phosphoinositide-3-kinase-interacting protein 1 (Fragment) OS=Homo sapiens GN=PIK3IP1 PE=4 SV=1 - - - - - - - K01343|1|5e-08|56.6|bta:281407|tissue plasminogen activator [EC:3.4.21.68]!K05122|5|2e-07|54.3|ame:413616|receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1] GO:0043553//negative regulation of phosphatidylinositol 3-kinase activity;GO:0014067//negative regulation of phosphatidylinositol 3-kinase cascade GO:0036313//phosphatidylinositol 3-kinase catalytic subunit binding;GO:0016301//kinase activity GO:0016021//integral to membrane 89 tr|B1AHA8|B1AHA8_HUMAN Heme oxygenase 1 (Fragment) OS=Homo sapiens GN=HMOX1 PE=1 SV=1 25525 MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMN 88 13.4 4 3 3 2 2 1.677 0.855 0.865 3 3 3 * - - 1.132333333 0.471721669 tr|B1AHA8|B1AHA8_HUMAN 100 2.00E-107 gi|24987883|pdb|1N3U|A Chain A, Crystal Structure Of Human Heme Oxygenase 1 (Ho-1) In Complex With Its Substrate Heme, Crystal Form B >gi|24987884|pdb|1N3U|B Chain B, Crystal Structure Of Human Heme Oxygenase 1 (Ho-1) In Complex With Its Substrate Heme, Crystal Form B >gi|27065997|pdb|1N45|A Chain A, X-Ray Crystal Structure Of Human Heme Oxygenase-1 (Ho-1) In Complex With Its Substrate Heme >gi|27065998|pdb|1N45|B Chain B, X-Ray Crystal Structure Of Human Heme Oxygenase-1 (Ho-1) In Complex With Its Substrate Heme >gi|34810855|pdb|1OZR|A Chain A, Crystal Structures Of The Ferric, Ferrous And Ferrous-No Forms Of The Asp140ala Mutant Of Human Heme Oxygenase-1: Catalytic Implications >gi|34810856|pdb|1OZR|B Chain B, Crystal Structures Of The Ferric, Ferrous And Ferrous-No Forms Of The Asp140ala Mutant Of Human Heme Oxygenase-1: Catalytic Implications >gi|34810857|pdb|1OZW|A Chain A, Crystal Structures Of The Ferric, Ferrous And Ferrous-No Forms Of The Asp140ala Mutant Of Human Heme Oxygenase-1: Catalytic Implications >gi|34810858|pdb|1OZW|B Chain B, Crystal Structures Of The Ferric, Ferrous And Ferrous-No Forms Of The Asp140ala Mutant Of Human Heme Oxygenase-1: Catalytic Implications >gi|51247342|pdb|1S8C|A Chain A, Crystal Structure Of Human Heme Oxygenase In A Complex With Biliverdine >gi|51247343|pdb|1S8C|B Chain B, Crystal Structure Of Human Heme Oxygenase In A Complex With Biliverdine >gi|51247344|pdb|1S8C|C Chain C, Crystal Structure Of Human Heme Oxygenase In A Complex With Biliverdine >gi|51247345|pdb|1S8C|D Chain D, Crystal Structure Of Human Heme Oxygenase In A Complex With Biliverdine >gi|52695420|pdb|1S13|A Chain A, Human Heme Oxygenase Oxidatition Of Alpha- And Gamma-Meso- Phenylhemes >gi|52695421|pdb|1S13|B Chain B, Human Heme Oxygenase Oxidatition Of Alpha- And Gamma-Meso- Phenylhemes >gi|52695624|pdb|1T5P|A Chain A, Human Heme Oxygenase Oxidation Of Alpha- And Gamma-Meso- Phenylhemes >gi|52695625|pdb|1T5P|B Chain B, Human Heme Oxygenase Oxidation Of Alpha- And Gamma-Meso- Phenylhemes >gi|71041630|pdb|1TWN|A Chain A, Crystal Structures Of Ferrous And Ferrous-No Forms Of Verdoheme In A Complex With Human Heme Oxygenase-1: Catalytic Implications For Heme Cleavage >gi|71041631|pdb|1TWN|B Chain B, Crystal Structures Of Ferrous And Ferrous-No Forms Of Verdoheme In A Complex With Human Heme Oxygenase-1: Catalytic Implications For Heme Cleavage >gi|71041632|pdb|1TWR|A Chain A, Crystal Structures Of Ferrous And Ferrous-No Forms Of Verdoheme In A Complex With Human Heme Oxygenase-1: Catalytic Implications For Heme Cleavage >gi|71041633|pdb|1TWR|B Chain B, Crystal Structures Of Ferrous And Ferrous-No Forms Of Verdoheme In A Complex With Human Heme Oxygenase-1: Catalytic Implications For Heme Cleavage >gi|208435604|pdb|3CZY|A Chain A, Crystal Structure Of Human Heme Oxygenase-1 In Complex With 1-(Adamantan-1-Yl)-2-(1h-Imidazol-1-Yl)ethanone >gi|208435605|pdb|3CZY|B Chain B, Crystal Structure Of Human Heme Oxygenase-1 In Complex With 1-(Adamantan-1-Yl)-2-(1h-Imidazol-1-Yl)ethanone >gi|254839439|pdb|3HOK|A Chain A, X-Ray Crystal Structure Of Human Heme Oxygenase-1 With (2r, 4s)-2-[2-(4-Chlorophenyl)ethyl]-2-[(1h-Imidazol-1-Yl) Methyl]-4[((5-Trifluoromethylpyridin-2-Yl)thio)methyl]-1,3- Dioxolane: A Novel, Inducible Binding Mode >gi|254839440|pdb|3HOK|B Chain B, X-Ray Crystal Structure Of Human Heme Oxygenase-1 With (2r, 4s)-2-[2-(4-Chlorophenyl)ethyl]-2-[(1h-Imidazol-1-Yl) Methyl]-4[((5-Trifluoromethylpyridin-2-Yl)thio)methyl]-1,3- Dioxolane: A Novel, Inducible Binding Mode >gi|281307136|pdb|3K4F|A Chain A, X-Ray Crystal Structure Of Human Heme Oxygenase-1 In Complex With 4-Phenyl-1-(1h-1,2,4-Triazol-1-Yl)-2-Butanone >gi|281307137|pdb|3K4F|B Chain B, X-Ray Crystal Structure Of Human Heme Oxygenase-1 In Complex With 4-Phenyl-1-(1h-1,2,4-Triazol-1-Yl)-2-Butanone >gi|374414582|pdb|3TGM|A Chain A, X-Ray Crystal Structure Of Human Heme Oxygenase-1 In Complex With 1- (1h-Imidazol-1-Yl)-4,4-Diphenyl-2 Butanone >gi|374414583|pdb|3TGM|B Chain B, X-Ray Crystal Structure Of Human Heme Oxygenase-1 In Complex With 1- (1h-Imidazol-1-Yl)-4,4-Diphenyl-2 Butanone 100 2.00E-108 sp|P09601|HMOX1_HUMAN Heme oxygenase 1 OS=Homo sapiens GN=HMOX1 PE=1 SV=1 100 5.00E-107 Q6FH11 Q6FH11_HUMAN HMOX1 protein OS=Homo sapiens GN=HMOX1 PE=2 SV=1 sll1184 179 2.00E-45 COG5398 Heme oxygenase P Inorganic ion transport and metabolism ; K00510|1|2e-108|390|hsa:3162|heme oxygenase [EC:1.14.99.3] GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0002246//wound healing involved in inflammatory response;GO:0043524//negative regulation of neuron apoptotic process;GO:0014806//smooth muscle hyperplasia;GO:0001935//endothelial cell proliferation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB cascade;GO:0042542//response to hydrogen peroxide;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0043392//negative regulation of DNA binding;GO:0045766//positive regulation of angiogenesis;GO:0071456//cellular response to hypoxia;GO:0008217//regulation of blood pressure;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0034383//low-density lipoprotein particle clearance;GO:0002686//negative regulation of leukocyte migration;GO:0051260//protein homooligomerization;GO:0044281//small molecule metabolic process;GO:0007588//excretion;GO:0007264//small GTPase mediated signal transduction;GO:0043627//response to estrogen stimulus;GO:0031670//cellular response to nutrient;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0045909//positive regulation of vasodilation;GO:0034101//erythrocyte homeostasis;GO:0043305//negative regulation of mast cell degranulation;GO:0042167//heme catabolic process;GO:0035094//response to nicotine;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0045080//positive regulation of chemokine biosynthetic process;GO:0006788//heme oxidation;GO:0032764//negative regulation of mast cell cytokine production;GO:0071276//cellular response to cadmium ion;GO:0055085//transmembrane transport;GO:0006879//cellular iron ion homeostasis GO:0004871//signal transducer activity;GO:0042803//protein homodimerization activity;GO:0004630//phospholipase D activity;GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0004392//heme oxygenase (decyclizing) activity;GO:0019899//enzyme binding GO:0005901//caveola;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005789//endoplasmic reticulum membrane 90 sp|Q9UBG0|MRC2_HUMAN C-type mannose receptor 2 OS=Homo sapiens GN=MRC2 PE=1 SV=2 184059 MGPGRPAPAPWPRHLLRCVLLLGCLHLGRPGAPGDAALPEPNVFLIFSHGLQGCLEAQGGQVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLRWHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQGNSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDALLLCESRNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLLLLALLTAALILYRRRQSIERGAFEGARYSRSSSSPTEATEKNILVSDMEMNEQQE 178 6 - 9 9 6 6 1.067 1.183 0.933 7 7 6 - - - 1.061 0.125107953 sp|Q9UBG0|MRC2_HUMAN 100 0 gi|110624774|ref|NP_006030.2| C-type mannose receptor 2 precursor [Homo sapiens] >gi|317373394|sp|Q9UBG0.2|MRC2_HUMAN RecName: Full=C-type mannose receptor 2; AltName: Full=C-type lectin domain family 13 member E; AltName: Full=Endocytic receptor 180; AltName: Full=Macrophage mannose receptor 2; AltName: Full=Urokinase-type plasminogen activator receptor-associated protein; Short=UPAR-associated protein; Short=Urokinase receptor-associated protein; AltName: CD_antigen=CD280; Flags: Precursor 100 0 sp|Q9UBG0|MRC2_HUMAN C-type mannose receptor 2 OS=Homo sapiens GN=MRC2 PE=1 SV=2 99.72 0 H2QDM3 H2QDM3_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000011028 PE=4 SV=1 - - - - - - - K06560|1|0.0|2880|hsa:9902|mannose receptor, C type GO:0006897//endocytosis GO:0030246//carbohydrate binding GO:0016021//integral to membrane 91 tr|B5BU24|B5BU24_HUMAN 14-3-3 protein beta/alpha OS=Homo sapiens GN=YWHAB PE=2 SV=1 34597 MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKMAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN 310 23.6 1 30 11 5 2 1.077 0.836 0.785 4 4 4 - * - 0.899333333 0.155962602 tr|B5BU24|B5BU24_HUMAN 100 2.00E-142 gi|197692221|dbj|BAG70074.1| 14-3-3 protein beta/alpha [Homo sapiens] >gi|197692473|dbj|BAG70200.1| 14-3-3 protein beta/alpha [Homo sapiens] 99.59 1.00E-142 sp|A4K2U9|1433B_PONAB 14-3-3 protein beta/alpha OS=Pongo abelii GN=YWHAB PE=3 SV=1 100 5.00E-142 B5BU24 B5BU24_HUMAN 14-3-3 protein beta/alpha OS=Homo sapiens GN=YWHAB PE=2 SV=1 YDR099w 319 2.00E-87 COG5040 14-3-3 family protein T Signal transduction mechanisms ; K06630|1|1e-142|505|ptr:458272|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein GO:0007411//axon guidance;GO:0035308//negative regulation of protein dephosphorylation;GO:0007265//Ras protein signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0000186//activation of MAPKK activity;GO:0006605//protein targeting;GO:0051220//cytoplasmic sequestering of protein;GO:0045892//negative regulation of transcription, DNA-dependent;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0000165//MAPK cascade;GO:0035329//hippo signaling cascade;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0016071//mRNA metabolic process GO:0003714//transcription corepressor activity;GO:0042826//histone deacetylase binding;GO:0008022//protein C-terminus binding;GO:0050815//phosphoserine binding;GO:0004497//monooxygenase activity;GO:0019904//protein domain specific binding GO:0017053//transcriptional repressor complex;GO:0042470//melanosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005813//centrosome;GO:0048471//perinuclear region of cytoplasm 92 sp|P02776|PLF4_HUMAN Platelet factor 4 OS=Homo sapiens GN=PF4 PE=1 SV=2 13861 MSSAAGFCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES 272 35.6 - 19 19 4 4 0.639 3.047 1.281 15 11 14 - - * 1.655666667 1.246955225 sp|P02776|PLF4_HUMAN 100 1.00E-23 gi|1110557|gb|AAB35135.1| PF 4-derived endothelial cell growth inhibitor peak II {N-terminal} [human, peripheral blood leukocytes, Peptide Partial, 54 aa] 100 2.00E-40 sp|P02776|PLF4_HUMAN Platelet factor 4 OS=Homo sapiens GN=PF4 PE=1 SV=2 100 9.00E-39 G3RHN6 G3RHN6_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=PF4 PE=4 SV=1 - - - - - - - K05407|1|2e-40|163|hsa:5196|platelet factor 4 GO:0016525//negative regulation of angiogenesis;GO:0010628//positive regulation of gene expression;GO:0030168//platelet activation;GO:0032760//positive regulation of tumor necrosis factor production;GO:0043066//negative regulation of apoptotic process;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0006955//immune response;GO:0045918//negative regulation of cytolysis;GO:0019221//cytokine-mediated signaling pathway;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0002576//platelet degranulation;GO:0045651//positive regulation of macrophage differentiation;GO:0045347//negative regulation of MHC class II biosynthetic process;GO:0030595//leukocyte chemotaxis GO:0008201//heparin binding;GO:0008009//chemokine activity GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space 93 sp|Q9Y696|CLIC4_HUMAN Chloride intracellular channel protein 4 OS=Homo sapiens GN=CLIC4 PE=1 SV=4 >tr|Q6FIC5|Q6FIC5_HUMAN CLIC4 protein OS=Homo sapiens GN=CLIC4 PE=2 SV=1 36891 MALSMPLNGLKEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLDGNEMTLADCNLLPKLHIVKVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKRLTK 157 24.5 - 14 14 6 6 0.88 0.598 0.679 5 5 5 - * - 0.719 0.145192975 sp|Q9Y696|CLIC4_HUMAN 100 2.00E-120 gi|119615548|gb|EAW95142.1| chloride intracellular channel 4, isoform CRA_a [Homo sapiens] 100 5.00E-147 sp|Q9Y696|CLIC4_HUMAN Chloride intracellular channel protein 4 OS=Homo sapiens GN=CLIC4 PE=1 SV=4 100 1.00E-145 F7EXF2 F7EXF2_CALJA Uncharacterized protein OS=Callithrix jacchus GN=LOC100389916 PE=4 SV=1 - - - - - - - K05024|1|6e-147|520|hsa:25932|chloride intracellular channel 4 GO:0001525//angiogenesis;GO:0071277//cellular response to calcium ion;GO:0030336//negative regulation of cell migration;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0001886//endothelial cell morphogenesis;GO:0009566//fertilization;GO:0051493//regulation of cytoskeleton organization;GO:0006821//chloride transport;GO:0007035//vacuolar acidification;GO:0034765//regulation of ion transmembrane transport;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0048754//branching morphogenesis of an epithelial tube;GO:0030216//keratinocyte differentiation;GO:0035264//multicellular organism growth GO:0005247//voltage-gated chloride channel activity;GO:0032403//protein complex binding GO:0005911//cell-cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0005773//vacuole;GO:0015629//actin cytoskeleton;GO:0005902//microvillus;GO:0005829//cytosol;GO:0009986//cell surface;GO:0005813//centrosome;GO:0030496//midbody;GO:0016363//nuclear matrix;GO:0045177//apical part of cell;GO:0048471//perinuclear region of cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0034707//chloride channel complex;GO:0005739//mitochondrion 94 sp|P19021|AMD_HUMAN Peptidyl-glycine alpha-amidating monooxygenase OS=Homo sapiens GN=PAM PE=1 SV=2 125850 MAGRVPSLLVLLVFPSSCLAFRSPLSVFKRFKETTRPFSNECLGTTRPVVPIDSSDFALDIRMPGVTPKQSDTYFCMSMRIPVDEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVVNSDISCHYKNYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKHAVSFMTCTQNVAPDMFRTIPPEANIPIPVKSDMVMMHEHHKETEYKDKIPLLQQPKREEEEVLDQGDFYSLLSKLLGEREDVVHVHKYNPTEKAESESDLVAEIANVVQKKDLGRSDAREGAEHERGNAILVRDRIHKFHRLVSTLRPPESRVFSLQQPPPGEGTWEPEHTGDFHMEEALDWPGVYLLPGQVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDTILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNYWVTDVALHQVFKLDPNNKEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTKEFVREIKHSSFGRNVFAISYIPGLLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKPVRKHFDMPHDIVASEDGTVYIGDAHTNTVWKFTLTEKLEHRSVKKAGIEVQEIKEAEAVVETKMENKPTSSELQKMQEKQKLIKEPGSGVPVVLITTLLVIPVVVLLAIAIFIRWKKSRAFGDSEHKLETSSGRVLGRFRGKGSGGLNLGNFFASRKGYSRKGFDRLSTEGSDQEKEDDGSESEEEYSAPLPALAPSSS 131 6.6 - 12 12 5 5 0.971 1.096 1.38 6 6 6 - - * 1.149 0.20958769 sp|P19021|AMD_HUMAN 100 0 gi|293336314|ref|NP_001170777.1| peptidyl-glycine alpha-amidating monooxygenase isoform e preproprotein [Homo sapiens] >gi|23503036|sp|P19021.2|AMD_HUMAN RecName: Full=Peptidyl-glycine alpha-amidating monooxygenase; Short=PAM; Includes: RecName: Full=Peptidylglycine alpha-hydroxylating monooxygenase; Short=PHM; Includes: RecName: Full=Peptidyl-alpha-hydroxyglycine alpha-amidating lyase; AltName: Full=Peptidylamidoglycolate lyase; Short=PAL; Flags: Precursor >gi|24430388|dbj|BAC22594.1| peptidylglycine alpha-amidating monooxygenase [Homo sapiens] >gi|119569470|gb|EAW49085.1| peptidylglycine alpha-amidating monooxygenase, isoform CRA_b [Homo sapiens] 100 0 sp|P19021|AMD_HUMAN Peptidyl-glycine alpha-amidating monooxygenase OS=Homo sapiens GN=PAM PE=1 SV=2 100 3.00E-73 E9PHD8 E9PHD8_HUMAN Peptidyl-glycine alpha-amidating monooxygenase OS=Homo sapiens GN=PAM PE=4 SV=1 all0422 70.9 1.00E-11 COG3391 Uncharacterized conserved protein S Function unknown ; K00504|1|0.0|1859|hsa:5066|peptidylglycine monooxygenase [EC:1.14.17.3] GO:0060173//limb development;GO:0007507//heart development;GO:0009268//response to pH;GO:0006355//regulation of transcription, DNA-dependent;GO:0051493//regulation of cytoskeleton organization;GO:0006518//peptide metabolic process;GO:0051384//response to glucocorticoid stimulus;GO:0032880//regulation of protein localization;GO:0016567//protein ubiquitination;GO:0046688//response to copper ion;GO:0001666//response to hypoxia;GO:0042493//response to drug;GO:0021785//branchiomotor neuron axon guidance;GO:0021952//central nervous system projection neuron axonogenesis;GO:0032355//response to estradiol stimulus GO:0008270//zinc ion binding;GO:0004598//peptidylamidoglycolate lyase activity;GO:0016874//ligase activity;GO:0004504//peptidylglycine monooxygenase activity;GO:0042803//protein homodimerization activity;GO:0031418//L-ascorbic acid binding;GO:0005507//copper ion binding GO:0030141//secretory granule;GO:0015630//microtubule cytoskeleton;GO:0016021//integral to membrane;GO:0005576//extracellular region;GO:0030424//axon;GO:0005634//nucleus;GO:0043204//perikaryon 95 tr|F5H5D3|F5H5D3_HUMAN Tubulin alpha-1C chain OS=Homo sapiens GN=TUBA1C PE=1 SV=1 65602 MTAWFNGVEELGRDECFVCLELDPSNGSFLNAKLYISNWILIYFTRTLQLPAPFNTCTSSKSRGEPGCDSKRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAVAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSADGEDEGEEY 708 22.9 3 42 5 9 1 0.337 0.247 0.233 4 5 4 * * * 0.272333333 0.056438757 tr|F5H5D3|F5H5D3_HUMAN 100 0 gi|14389309|ref|NP_116093.1| tubulin alpha-1C chain [Homo sapiens] >gi|20455322|sp|Q9BQE3.1|TBA1C_HUMAN RecName: Full=Tubulin alpha-1C chain; AltName: Full=Alpha-tubulin 6; AltName: Full=Tubulin alpha-6 chain >gi|13436317|gb|AAH04949.1| Tubulin, alpha 1c [Homo sapiens] >gi|13543589|gb|AAH05946.1| Tubulin, alpha 1c [Homo sapiens] >gi|15080013|gb|AAH11790.1| Tubulin, alpha 1c [Homo sapiens] >gi|17939496|gb|AAH19298.1| Tubulin, alpha 1c [Homo sapiens] >gi|18088050|gb|AAH21088.1| Tubulin, alpha 1c [Homo sapiens] >gi|30410987|gb|AAH51297.1| Tubulin, alpha 1c [Homo sapiens] >gi|38648679|gb|AAH63036.1| Tubulin, alpha 1c [Homo sapiens] >gi|119578461|gb|EAW58057.1| tubulin, alpha 6 [Homo sapiens] 100 0 sp|Q9BQE3|TBA1C_HUMAN Tubulin alpha-1C chain OS=Homo sapiens GN=TUBA1C PE=1 SV=1 100 0 H2NH68 H2NH68_PONAB Uncharacterized protein OS=Pongo abelii GN=LOC100446260 PE=3 SV=1 SPBC800.05c 723 0 COG5023 Tubulin Z Cytoskeleton ; K07374|1|0.0|1021|pon:100446260|tubulin alpha GO:0030705//cytoskeleton-dependent intracellular transport;GO:0051301//cell division;GO:0006184//GTP catabolic process;GO:0051258//protein polymerization;GO:0055085//transmembrane transport;GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement;GO:0051084//'de novo' posttranslational protein folding GO:0005198//structural molecule activity;GO:0005525//GTP binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0003924//GTPase activity;GO:0005524//ATP binding GO:0016021//integral to membrane;GO:0005881//cytoplasmic microtubule 96 tr|V9HW25|V9HW25_HUMAN Epididymis secretory protein Li 273 OS=Homo sapiens GN=HEL-S-273 PE=2 SV=1 43674 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 2086 28.5 - 138 23 9 1 0.334 0.32 0.328 15 16 16 * * * 0.327333333 0.007023769 tr|V9HW25|V9HW25_HUMAN 100 2.00E-69 gi|6573280|gb|AAF17621.1| beta tropomyosin [Homo sapiens] 87.32 2.00E-63 sp|P07951|TPM2_HUMAN Tropomyosin beta chain OS=Homo sapiens GN=TPM2 PE=1 SV=1 100 1.00E-84 F7GT13 F7GT13_MACMU Tropomyosin beta chain isoform 2 OS=Macaca mulatta GN=TPM2 PE=2 SV=1 - - - - - - - K10374|1|6e-86|317|ecb:100055542|tropomyosin 2 GO:0043462//regulation of ATPase activity;GO:0030049//muscle filament sliding GO:0008307//structural constituent of muscle;GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton GO:0005829//cytosol;GO:0005862//muscle thin filament tropomyosin 97 sp|Q641Q3|METRL_HUMAN Meteorin-like protein OS=Homo sapiens GN=METRNL PE=2 SV=1 36772 MRGAARAAWGRAGQPWPRPPAPGPPPPPLPLLLLLLAGLLGGAGAQYSSDRCSWKGSGLTHEAHRKEVEQVYLRCAAGAVEWMYPTGALIVNLRPNTFSPARHLTVCIRSFTDSSGANIYLEKTGELRLLVPDGDGRPGRVQCFGLEQGGLFVEATPQQDIGRRTTGFQYELVRRHRASDLHELSAPCRPCSDTEVLLAVCTSDFAVRGSIQQVTHEPERQDSAIHLRVSRLYRQKSRVFEPVPEGDGHWQGRVRTLLECGVRPGHGDFLFTGHMHFGEARLGCAPRFKDFQRMYRDAQERGLNPCEVGTD 75 9.3 - 2 2 2 2 0.776 0.901 0.853 2 2 2 * - - 0.843333333 0.063058174 sp|Q641Q3|METRL_HUMAN 100 3.00E-147 gi|30047763|gb|AAH50568.1| METRNL protein, partial [Homo sapiens] 100 7.00E-156 sp|Q641Q3|METRL_HUMAN Meteorin-like protein OS=Homo sapiens GN=METRNL PE=2 SV=1 100 6.00E-131 B3KSJ5 B3KSJ5_HUMAN cDNA FLJ36429 fis, clone THYMU2011573, highly similar to Homo sapiens meteorin, glial cell differentiation regulator-like (METRNL), mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K00901|1|6e-45|181|bfo:BRAFLDRAFT_118688|diacylglycerol kinase [EC:2.7.1.107] - - GO:0005576//extracellular region 98 tr|B4DRB7|B4DRB7_HUMAN cDNA FLJ54136, highly similar to Proactivator polypeptide OS=Homo sapiens PE=2 SV=1 73627 MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHYLQTVWNKPTVKSLPCVICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYPQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKDVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEIPAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 2860 34.2 - 175 10 16 2 1.297 1.123 1.309 8 8 8 - - * 1.243 0.104096109 tr|B4DRB7|B4DRB7_HUMAN 100 3.00E-27 gi|253722986|pdb|1M12|A Chain A, Nmr Solution Structure Of Human Saposin C >gi|253723109|pdb|1SN6|A Chain A, Nmr Solution Structure Of Human Saposin C In Sds Micelles 98.61 0 sp|P07602|SAP_HUMAN Proactivator polypeptide OS=Homo sapiens GN=PSAP PE=1 SV=2 100 0 B4DRB7 B4DRB7_HUMAN cDNA FLJ54136, highly similar to Proactivator polypeptide OS=Homo sapiens PE=2 SV=1 - - - - - - - K12382|1|0.0|961|hsa:5660|saposin GO:0007585//respiratory gaseous exchange;GO:0030168//platelet activation;GO:0006869//lipid transport;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043408//regulation of MAPK cascade;GO:0060736//prostate gland growth;GO:0071310//cellular response to organic substance;GO:0019216//regulation of lipid metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0043065//positive regulation of apoptotic process;GO:0044281//small molecule metabolic process;GO:0002576//platelet degranulation;GO:0045161//neuronal ion channel clustering;GO:0060742//epithelial cell differentiation involved in prostate gland development;GO:0006644//phospholipid metabolic process GO:0030246//carbohydrate binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005319//lipid transporter activity;GO:0008289//lipid binding GO:0005615//extracellular space;GO:0005743//mitochondrial inner membrane;GO:0016021//integral to membrane;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005581//collagen;GO:0043202//lysosomal lumen 99 tr|Q5UGI6|Q5UGI6_HUMAN Serine/cysteine proteinase inhibitor clade G member 1 splice variant 2 (Fragment) OS=Homo sapiens GN=SERPING1 PE=2 SV=1 44679 GLQADPADPPAAAAGWGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMLHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDPRA 196 6.3 3 16 16 2 2 0.564 0.31 0.679 9 9 5 * * - 0.517666667 0.188812959 tr|Q5UGI6|Q5UGI6_HUMAN 100 1.00E-59 gi|14192835|dbj|BAB55877.1| complement C1 inhibitor [Pan troglodytes] >gi|14192837|dbj|BAB55878.1| complement C1 inhibitor [Pan troglodytes] 99.68 1.00E-177 sp|P05155|IC1_HUMAN Plasma protease C1 inhibitor OS=Homo sapiens GN=SERPING1 PE=1 SV=2 100 5.00E-59 Q95J66 Q95J66_PANTR Complement C1 inhibitor (Fragment) OS=Pan troglodytes GN=SERPING1 PE=4 SV=1 all0778 103 6.00E-22 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K04001|1|2e-177|622|hsa:710|C1 inhibitor GO:0030168//platelet activation;GO:0001869//negative regulation of complement activation, lectin pathway;GO:0010951//negative regulation of endopeptidase activity;GO:0008015//blood circulation;GO:0042730//fibrinolysis;GO:0007597//blood coagulation, intrinsic pathway;GO:0006958//complement activation, classical pathway;GO:0002576//platelet degranulation;GO:0006508//proteolysis GO:0005515//protein binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008233//peptidase activity GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space 100 sp|P29373|RABP2_HUMAN Cellular retinoic acid-binding protein 2 OS=Homo sapiens GN=CRABP2 PE=1 SV=2 20113 MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGELILTMTADDVVCTRVYVRE 63 24.6 - 3 3 3 3 1.843 2.989 2.81 2 2 2 - - * 2.547333333 0.61650169 sp|P29373|RABP2_HUMAN 100 5.00E-75 gi|4503029|ref|NP_001869.1| cellular retinoic acid-binding protein 2 [Homo sapiens] >gi|315013542|ref|NP_001186652.1| cellular retinoic acid-binding protein 2 [Homo sapiens] >gi|132401|sp|P29373.2|RABP2_HUMAN RecName: Full=Cellular retinoic acid-binding protein 2; AltName: Full=Cellular retinoic acid-binding protein II; Short=CRABP-II >gi|181026|gb|AAA52068.1| retinoic acid binding protein II [Homo sapiens] >gi|181030|gb|AAA58430.1| retinoic acid-binding protein II [Homo sapiens] >gi|12654551|gb|AAH01109.1| Cellular retinoic acid binding protein 2 [Homo sapiens] >gi|47496661|emb|CAG29353.1| CRABP2 [Homo sapiens] >gi|54696516|gb|AAV38630.1| cellular retinoic acid binding protein 2 [Homo sapiens] >gi|119573306|gb|EAW52921.1| cellular retinoic acid binding protein 2, isoform CRA_a [Homo sapiens] >gi|119573307|gb|EAW52922.1| cellular retinoic acid binding protein 2, isoform CRA_a [Homo sapiens] >gi|326205172|dbj|BAJ83972.1| cellular retinoic acid binding protein 2 [Homo sapiens] 100 6.00E-76 sp|P29373|RABP2_HUMAN Cellular retinoic acid-binding protein 2 OS=Homo sapiens GN=CRABP2 PE=1 SV=2 100 2.00E-74 F1T098 F1T098_HUMAN Cellular retinoic acid binding protein 2 OS=Homo sapiens GN=CRABP2 PE=2 SV=1 - - - - - - - K08754|1|3e-23|107|acs:100555334|fatty acid-binding protein 5, epidermal!K08752|2|3e-23|106|mmu:14077|fatty acid-binding protein 3, muscle and heart!K08756|3|5e-23|106|acs:100562795|fatty acid-binding protein 7, brain GO:0006810//transport;GO:0035115//embryonic forelimb morphogenesis;GO:0006355//regulation of transcription, DNA-dependent;GO:0008544//epidermis development;GO:0042573//retinoic acid metabolic process;GO:0007165//signal transduction GO:0001972//retinoic acid binding;GO:0019841//retinol binding;GO:0005215//transporter activity;GO:0016918//retinal binding GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum 101 sp|P07237|PDIA1_HUMAN Protein disulfide-isomerase OS=Homo sapiens GN=P4HB PE=1 SV=3 >tr|A0A024R8S5|A0A024R8S5_HUMAN Protein disulfide-isomerase OS=Homo sapiens GN=P4HB PE=3 SV=1 72082 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL 1009 32.1 - 86 86 15 15 0.749 0.541 0.775 52 52 52 - * * 0.688333333 0.128254954 sp|P07237|PDIA1_HUMAN 100 0 gi|426346301|ref|XP_004040818.1| PREDICTED: protein disulfide-isomerase [Gorilla gorilla gorilla] 100 0 sp|P07237|PDIA1_HUMAN Protein disulfide-isomerase OS=Homo sapiens GN=P4HB PE=1 SV=3 100 8.00E-87 B3KTQ9 B3KTQ9_HUMAN Procollagen-proline, 2-oxoglutarate 4-dioxygenase (Proline 4-hydroxylase), beta polypeptide, isoform CRA_b OS=Homo sapiens GN=P4HB PE=2 SV=1 SPAC1F5.02 272 1.00E-72 COG0526 Thiol-disulfide isomerase and thioredoxins OC Posttranslational modification, protein turnover, chaperones ; Energy production and conversion ; K09580|1|0.0|945|hsa:5034|protein disulfide-isomerase A1 [EC:5.3.4.1] GO:0006662//glycerol ether metabolic process;GO:0006629//lipid metabolic process;GO:0045454//cell redox homeostasis;GO:0042157//lipoprotein metabolic process;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0030198//extracellular matrix organization GO:0003756//protein disulfide isomerase activity;GO:0004656//procollagen-proline 4-dioxygenase activity;GO:0009055//electron carrier activity;GO:0046982//protein heterodimerization activity;GO:0015035//protein disulfide oxidoreductase activity GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0009986//cell surface;GO:0042470//melanosome;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005886//plasma membrane 102 tr|A0A024R895|A0A024R895_HUMAN SET translocation (Myeloid leukemia-associated), isoform CRA_b OS=Homo sapiens GN=SET PE=3 SV=1 38472 MSAPAAKVSKKELNSNHDGADETSEKEQQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQNKASRKRQHEEPESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYLVPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEGEDD 216 12.6 2 11 11 3 3 3.534 1.697 3.165 9 9 8 * * - 2.798666667 0.971747052 tr|A0A024R895|A0A024R895_HUMAN 100 3.00E-115 gi|397503558|ref|XP_003822389.1| PREDICTED: protein SET isoform 2 [Pan paniscus] 99.5 3.00E-116 sp|Q9EQU5|SET_MOUSE Protein SET OS=Mus musculus GN=Set PE=1 SV=1 100 1.00E-114 Q5VXV2 Q5VXV2_HUMAN Protein SET OS=Homo sapiens GN=SET PE=2 SV=2 - - - - - - - K11290|1|7e-133|473|mdo:100013223|template-activating factor I GO:0006913//nucleocytoplasmic transport;GO:0006337//nucleosome disassembly;GO:0045892//negative regulation of transcription, DNA-dependent;GO:0035067//negative regulation of histone acetylation;GO:0043524//negative regulation of neuron apoptotic process;GO:0006334//nucleosome assembly;GO:0016071//mRNA metabolic process;GO:0006260//DNA replication GO:0042393//histone binding;GO:0003677//DNA binding;GO:0004864//protein phosphatase inhibitor activity;GO:0008601//protein phosphatase type 2A regulator activity GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0043234//protein complex;GO:0048471//perinuclear region of cytoplasm;GO:0005783//endoplasmic reticulum 103 tr|B3KXC3|B3KXC3_HUMAN Ferritin OS=Homo sapiens PE=2 SV=1 25612 MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWEGGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDNES 83 14.2 5 5 5 2 2 0.55 0.67 0.838 2 2 2 - - - 0.686 0.144665131 tr|B3KXC3|B3KXC3_HUMAN 100 3.00E-105 gi|193785282|dbj|BAG54435.1| unnamed protein product [Homo sapiens] 99.45 2.00E-105 sp|P02794|FRIH_HUMAN Ferritin heavy chain OS=Homo sapiens GN=FTH1 PE=1 SV=2 100 1.00E-104 B3KXC3 B3KXC3_HUMAN Ferritin OS=Homo sapiens PE=2 SV=1 AF0834 87.4 1.00E-17 COG1528 Ferritin-like protein P Inorganic ion transport and metabolism ; K00522|1|1e-106|384|ptr:738986|ferritin heavy chain [EC:1.16.3.1] GO:0055085//transmembrane transport;GO:0055114//oxidation-reduction process;GO:0006892//post-Golgi vesicle-mediated transport;GO:0016044//cellular membrane organization;GO:0006955//immune response;GO:0006880//intracellular sequestering of iron ion;GO:0006826//iron ion transport;GO:0048147//negative regulation of fibroblast proliferation GO:0008199//ferric iron binding;GO:0004322//ferroxidase activity;GO:0005515//protein binding GO:0008043//intracellular ferritin complex;GO:0005829//cytosol;GO:0005739//mitochondrion 104 tr|F5H442|F5H442_HUMAN Tumor susceptibility gene 101 protein OS=Homo sapiens GN=TSG101 PE=1 SV=1 48668 MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIPVPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPPNPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRWRMKEEMDRAQAELNALKRTEEDLKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSSALEKMENQSENNDIDEVIIPTAPLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFLKTSVP 59 5.5 1 2 2 2 2 1.051 --- --- 2 1 1 - - - 1.051 - tr|F5H442|F5H442_HUMAN 100 4.00E-160 gi|114324808|gb|ABI63717.1| tumor susceptibility protein 101 [Macaca mulatta] 100 0 sp|Q99816|TS101_HUMAN Tumor susceptibility gene 101 protein OS=Homo sapiens GN=TSG101 PE=1 SV=2 100 3.00E-161 Q09H93 Q09H93_MACMU Tumor susceptibility protein 101 (Fragment) OS=Macaca mulatta GN=TSG101 PE=2 SV=1 - - - - - - - K12183|1|0.0|651|mcc:693787|ESCRT-I complex subunit TSG101 GO:0016044//cellular membrane organization;GO:0001558//regulation of cell growth;GO:0006513//protein monoubiquitination;GO:0046755//non-lytic virus budding;GO:0015031//protein transport;GO:0051301//cell division;GO:0045892//negative regulation of transcription, DNA-dependent;GO:0008285//negative regulation of cell proliferation;GO:0007050//cell cycle arrest;GO:0008333//endosome to lysosome transport;GO:0030216//keratinocyte differentiation;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0046788//egress of virus within host cell GO:0003714//transcription corepressor activity;GO:0048306//calcium-dependent protein binding;GO:0043130//ubiquitin binding;GO:0031625//ubiquitin protein ligase binding;GO:0003677//DNA binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity GO:0005730//nucleolus;GO:0031902//late endosome membrane;GO:0005771//multivesicular body;GO:0005769//early endosome;GO:0005886//plasma membrane 105 sp|O76003|GLRX3_HUMAN Glutaredoxin-3 OS=Homo sapiens GN=GLRX3 PE=1 SV=2 46820 MAAGAAEAAVAAVEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPELTKKVQRHASSGSFLPSANEHLKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKAYSSWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKAYSNWPTYPQLYVKGELVGGLDIVKELKENGELLPILRGEN 87 11.6 - 5 5 3 3 0.893 0.658 0.597 3 2 3 - - - 0.716 0.156291395 sp|O76003|GLRX3_HUMAN 100 0 gi|3646128|emb|CAA09375.1| thioredoxin-like protein [Homo sapiens] 100 0 sp|O76003|GLRX3_HUMAN Glutaredoxin-3 OS=Homo sapiens GN=GLRX3 PE=1 SV=2 99.68 0 H2NC02 H2NC02_PONAB Uncharacterized protein OS=Pongo abelii GN=LOC100457689 PE=4 SV=1 YDR098c_2 128 1.00E-29 COG0278 Glutaredoxin-related protein O Posttranslational modification, protein turnover, chaperones ; K07390|1|7e-23|108|dan:Dana_GF19438|monothiol glutaredoxin GO:0002026//regulation of the force of heart contraction;GO:0055114//oxidation-reduction process;GO:0045454//cell redox homeostasis;GO:0010614//negative regulation of cardiac muscle hypertrophy GO:0005080//protein kinase C binding;GO:0051536//iron-sulfur cluster binding;GO:0046872//metal ion binding;GO:0009055//electron carrier activity;GO:0015035//protein disulfide oxidoreductase activity GO:0030018//Z disc;GO:0005938//cell cortex 106 tr|A0A024RDL9|A0A024RDL9_HUMAN Phosphoserine phosphatase, isoform CRA_b OS=Homo sapiens GN=PSPH PE=4 SV=1 33160 MACTWRARAQGRAEAPQWPARRKILPAMVSHSELRKLFYSADAVCFDVDSTVIREEGIDELAKICGVEDAVSEMTRRAMGGAVPFKAALTERLALIQPSREQVQRLIAEQPPHLTPGIRELVSRLQERNVQVFLISGGFRSIVEHVASKLNIPATNVFANRLKFYFNGEYAGFDETQPTAESGGKGKVIKLLKEKFHFKKIIMIGDGATDMEACPPADAFIGFGGNVIRQQVKDNAKWYITDFVELLGELEE 68 9.5 3 3 3 2 2 1.049 1.86 1.226 2 2 2 - - - 1.378333333 0.426420372 tr|A0A024RDL9|A0A024RDL9_HUMAN 100 2.00E-146 gi|119628375|gb|EAX07970.1| phosphoserine phosphatase, isoform CRA_b [Homo sapiens] >gi|119628376|gb|EAX07971.1| phosphoserine phosphatase, isoform CRA_b [Homo sapiens] 100 5.00E-130 sp|Q5RB83|SERB_PONAB Phosphoserine phosphatase OS=Pongo abelii GN=PSPH PE=2 SV=1 100 7.00E-105 C9JBI3 C9JBI3_HUMAN Phosphoserine phosphatase (Fragment) OS=Homo sapiens GN=PSPH PE=4 SV=1 PA4960_2 92.8 5.00E-19 COG0560 Phosphoserine phosphatase E Amino acid transport and metabolism ; K01079|1|5e-130|463|pon:100189699|phosphoserine phosphatase [EC:3.1.3.3] GO:0033574//response to testosterone stimulus;GO:0009612//response to mechanical stimulus;GO:0016311//dephosphorylation;GO:0031667//response to nutrient levels;GO:0034641//cellular nitrogen compound metabolic process;GO:0006564//L-serine biosynthetic process GO:0005509//calcium ion binding;GO:0000287//magnesium ion binding;GO:0004647//phosphoserine phosphatase activity;GO:0042803//protein homodimerization activity GO:0005829//cytosol 107 tr|Q8IYQ9|Q8IYQ9_HUMAN Importin subunit alpha OS=Homo sapiens GN=KPNA3 PE=2 SV=1 66287 MAENPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQDIVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFQNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQDVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEIIDQYFSGDDIDEDPCLIPEATQGGTYNFDPTANLQTKEFNF 86 6 2 3 3 3 3 1.868 1.115 0.917 2 2 2 - - - 1.3 0.501765882 tr|Q8IYQ9|Q8IYQ9_HUMAN 100 0 gi|23272453|gb|AAH35090.1| Karyopherin alpha 3 (importin alpha 4) [Homo sapiens] 99.23 0 sp|O00505|IMA3_HUMAN Importin subunit alpha-3 OS=Homo sapiens GN=KPNA3 PE=1 SV=2 100 0 Q8IYQ9 Q8IYQ9_HUMAN Importin subunit alpha OS=Homo sapiens GN=KPNA3 PE=2 SV=1 SPBC1604.08c 447 2.00E-125 COG5064 Karyopherin (importin) alpha U Intracellular trafficking, secretion, and vesicular transport ; K15043|1|4e-151|535|spu:583874|importin subunit alpha-2 GO:0019221//cytokine-mediated signaling pathway;GO:0006461//protein complex assembly;GO:0006607//NLS-bearing substrate import into nucleus;GO:0019048//virus-host interaction GO:0008565//protein transporter activity;GO:0008022//protein C-terminus binding;GO:0008139//nuclear localization sequence binding GO:0005829//cytosol;GO:0005643//nuclear pore;GO:0005654//nucleoplasm 108 tr|F6X2W2|F6X2W2_HUMAN Neuronal growth regulator 1 OS=Homo sapiens GN=NEGR1 PE=4 SV=1 37849 VICRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITGSADVLFSCWYLVLTLSSFTSIFYLKNAILQ 105 7.7 1 5 5 2 2 0.847 1.453 1.219 3 3 3 - - - 1.173 0.305607592 tr|F6X2W2|F6X2W2_HUMAN 100 1.00E-130 gi|22477847|gb|AAH36771.1| NEGR1 protein [Homo sapiens] 99.33 1.00E-175 sp|Q7Z3B1|NEGR1_HUMAN Neuronal growth regulator 1 OS=Homo sapiens GN=NEGR1 PE=1 SV=3 100 4.00E-130 Q8N440 Q8N440_HUMAN NEGR1 protein OS=Homo sapiens GN=NEGR1 PE=2 SV=1 - - - - - - - K06775|1|1e-175|615|hsa:257194|neuronal growth regulator 1 GO:0007155//cell adhesion GO:0005515//protein binding GO:0031225//anchored to membrane;GO:0043025//neuronal cell body;GO:0030425//dendrite;GO:0005886//plasma membrane 109 tr|W6I206|W6I206_HUMAN Lysyl oxidase-like 2 delta e13 OS=Homo sapiens GN=LOXL2 PE=2 SV=1 94700 MERPLCSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETAPDLVLNAEMVQQTTYLEDRPMFLLQCAMEENCLSASAAQTDPTTGYRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLNGTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVPSAKRRKKSLSTSAGS 303 11.1 2 12 12 5 5 0.47 0.357 0.327 10 9 9 * * * 0.384666667 0.07540778 tr|W6I206|W6I206_HUMAN 100 0 gi|12653633|gb|AAH00594.1| Lysyl oxidase-like 2 [Homo sapiens] >gi|119584029|gb|EAW63625.1| lysyl oxidase-like 2, isoform CRA_a [Homo sapiens] 99.86 0 sp|Q9Y4K0|LOXL2_HUMAN Lysyl oxidase homolog 2 OS=Homo sapiens GN=LOXL2 PE=1 SV=1 100 5.00E-70 E5RJL2 E5RJL2_HUMAN Lysyl oxidase homolog 2 (Fragment) OS=Homo sapiens GN=LOXL2 PE=4 SV=1 - - - - - - - K00280|1|0.0|1447|hsa:4017|lysyl oxidase-like protein 2/3/4 [EC:1.4.3.-] GO:0043542//endothelial cell migration;GO:0032332//positive regulation of chondrocyte differentiation;GO:0007155//cell adhesion;GO:0001837//epithelial to mesenchymal transition;GO:0016570//histone modification;GO:0001935//endothelial cell proliferation;GO:0007568//aging;GO:0002040//sprouting angiogenesis;GO:0018277//protein deamination;GO:0045892//negative regulation of transcription, DNA-dependent;GO:0001666//response to hypoxia;GO:0030199//collagen fibril organization;GO:0055114//oxidation-reduction process GO:0003714//transcription corepressor activity;GO:0004720//protein-lysine 6-oxidase activity;GO:0009055//electron carrier activity;GO:0005044//scavenger receptor activity;GO:0003682//chromatin binding;GO:0005507//copper ion binding;GO:0035064//methylated histone residue binding GO:0005604//basement membrane;GO:0016020//membrane;GO:0005615//extracellular space;GO:0005694//chromosome;GO:0005634//nucleus 110 sp|Q99584|S10AD_HUMAN Protein S100-A13 OS=Homo sapiens GN=S100A13 PE=1 SV=1 15723 MAAEPLTELEESIETVVTTFFTFARQEGRKDSLSVNEFKELVTQQLPHLLKDVGSLDEKMKSLDVNQDSELKFNEYWRLIGELAKEIRKKKDLKIRKK 248 32.7 - 14 14 3 3 0.943 0.764 0.663 11 11 11 - * * 0.79 0.141799154 sp|Q99584|S10AD_HUMAN 100 3.00E-21 gi|119573681|gb|EAW53296.1| S100 calcium binding protein A13, isoform CRA_a [Homo sapiens] >gi|119573682|gb|EAW53297.1| S100 calcium binding protein A13, isoform CRA_a [Homo sapiens] >gi|119573685|gb|EAW53300.1| S100 calcium binding protein A13, isoform CRA_a [Homo sapiens] 100 1.00E-42 sp|Q99584|S10AD_HUMAN Protein S100-A13 OS=Homo sapiens GN=S100A13 PE=1 SV=1 100 1.00E-20 D3DV53 D3DV53_HUMAN S100 calcium binding protein A13, isoform CRA_a (Fragment) OS=Homo sapiens GN=S100A13 PE=4 SV=1 - - - - - - - K10384|1|1e-06|51.2|aml:100480898|filaggrin!K14734|3|3e-06|50.4|ecb:100033995|S100 calcium binding protein G GO:0043303//mast cell degranulation;GO:0008360//regulation of cell shape;GO:0050703//interleukin-1 alpha secretion;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB cascade;GO:0051602//response to electrical stimulus;GO:0046688//response to copper ion;GO:0008284//positive regulation of cell proliferation GO:0050786//RAGE receptor binding;GO:0008144//drug binding;GO:0005507//copper ion binding;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0008289//lipid binding;GO:0017134//fibroblast growth factor binding;GO:0042803//protein homodimerization activity GO:0005829//cytosol;GO:0005615//extracellular space;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus 111 tr|Q32Q10|Q32Q10_HUMAN RSU1 protein (Fragment) OS=Homo sapiens GN=RSU1 PE=2 SV=1 37291 GETGRVRCSVPVLQGVRAAGVRSAEACGCTPIVLGATFRVTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQVFKAENNPWVTPIADQFQLGVSHVFEYIRSETYKYLYGRHMQANPEPPKKNNDKSKKISRKPLAAKNR 209 18.2 1 12 12 4 4 0.656 0.628 0.596 7 7 5 - - - 0.626666667 0.030022214 tr|Q32Q10|Q32Q10_HUMAN 100 4.00E-161 gi|79158545|gb|AAI07899.1| RSU1 protein [Homo sapiens] 100 7.00E-137 sp|Q15404|RSU1_HUMAN Ras suppressor protein 1 OS=Homo sapiens GN=RSU1 PE=1 SV=3 100 1.00E-160 Q32Q10 Q32Q10_HUMAN RSU1 protein (Fragment) OS=Homo sapiens GN=RSU1 PE=2 SV=1 MA2301_1 99.8 5.00E-21 COG4886 Leucine-rich repeat (LRR) protein S Function unknown ; K12796|1|5e-20|98.6|xtr:780049|erbb2-interacting protein GO:0034329//cell junction assembly;GO:0007265//Ras protein signal transduction - GO:0005829//cytosol 112 tr|A0A024R755|A0A024R755_HUMAN Calumenin, isoform CRA_a OS=Homo sapiens GN=CALU PE=4 SV=1 45743 MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKTFDQLTPEESKERLGMIVDKIDADKDGFVTEGELKSWIKHAQKKYIYDNVENQWQEFDMNQDGLISWDEYRNVTYGTYLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF 959 33 1 58 4 9 2 0.688 0.601 0.606 4 4 4 - - * 0.631666667 0.048850111 tr|A0A024R755|A0A024R755_HUMAN 100 0 gi|332224392|ref|XP_003261350.1| PREDICTED: calumenin isoform 5 [Nomascus leucogenys] 99.05 0 sp|Q3T0K1|CALU_BOVIN Calumenin OS=Bos taurus GN=CALU PE=2 SV=1 100 0 G1RPA7 G1RPA7_NOMLE Uncharacterized protein (Fragment) OS=Nomascus leucogenys GN=CALU PE=4 SV=1 - - - - - - - - GO:0030168//platelet activation;GO:0043086//negative regulation of catalytic activity;GO:0002576//platelet degranulation GO:0005509//calcium ion binding;GO:0019899//enzyme binding;GO:0004857//enzyme inhibitor activity GO:0033018//sarcoplasmic reticulum lumen;GO:0042470//melanosome;GO:0005576//extracellular region;GO:0005794//Golgi apparatus 113 tr|B2RDX5|B2RDX5_HUMAN cDNA, FLJ96812, highly similar to Homo sapiens threonyl-tRNA synthetase (TARS), mRNA OS=Homo sapiens PE=2 SV=1 101226 MGGEEKPIGAGEEKQKEGGKKKNKEGSGDGGRAELNPWPEYIYTRLEMYNILKAEHDSILAEKAEKDSKPIKVTLPDGKQVDAESWKTTPYQIACGISQGLADNTVIAKVNNVVWDLDRPLEEDCTLELLKFEDEEAQAVYWHSSAHIMGEAMERVYGGCLCYGPPIENGFYYDMYLEEGGVSSNDFSSLEALCKKIIKEKQAFERLEVKKETLLAMFKYNKFKCRILNEKVNTPTTTVYRCGPLIDLCRGPHVRHTGKIKALKIHKNSSTYWEGKADMETLQRIYGISFPDPKMLKEWEKFQEEAKNRDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRAVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFTLVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF 106 7.9 5 8 8 5 5 0.848 0.875 0.439 4 4 3 - - * 0.720666667 0.244303773 tr|B2RDX5|B2RDX5_HUMAN 100 0 gi|189055088|dbj|BAG38072.1| unnamed protein product [Homo sapiens] 99.72 0 sp|P26639|SYTC_HUMAN Threonine--tRNA ligase, cytoplasmic OS=Homo sapiens GN=TARS PE=1 SV=3 100 0 B2RDX5 B2RDX5_HUMAN cDNA, FLJ96812, highly similar to Homo sapiens threonyl-tRNA synthetase (TARS), mRNA OS=Homo sapiens PE=2 SV=1 YIL078w 809 0 COG0441 Threonyl-tRNA synthetase J Translation, ribosomal structure and biogenesis ; K01868|1|0.0|1427|hsa:6897|threonyl-tRNA synthetase [EC:6.1.1.3] GO:0006435//threonyl-tRNA aminoacylation GO:0046872//metal ion binding;GO:0004829//threonine-tRNA ligase activity;GO:0005524//ATP binding;GO:0042803//protein homodimerization activity GO:0005829//cytosol;GO:0015629//actin cytoskeleton 114 tr|A4QPB0|A4QPB0_HUMAN IQ motif containing GTPase activating protein 1 OS=Homo sapiens GN=IQGAP1 PE=2 SV=1 230857 MSAADEVDGLGVARPHYGSVLDNERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFKLGLAPQIQDLYGKVDFTEEEINNMKTELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIDRRIPADTFAALKNPNAMLVNLEEPLASTYQDILYQAKQDKMTNAKNRTENSERERDVYEELLTQAEIQGNINKVNTFSALANIDLALEQGDALALFRALQSPALGLRGLQQQNSDWYLKQLLSDKQQKRQSGQTDPLQKEELQSGVDAANSAAQQYQRRLAAVALINAAIQKGVAEKTVLELMNPEAQLPQVYPFAADLYQKELVTLQRQSPEHNLTHPELSVAVEMLSSVALINRALESGDVNTVWKQLSSSVTGLTNIEEENCQRYLDELMKLKAQAHAENNEFITWNDIQACVDHVNLVVQEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGVLAEVAQHYQDTLIRAKREKAQEIQDESAVLWLDEIQGGIWQSNKDTQEAQKFALGIFAINEAVESGDVGKTLSALRSPDVGLYGVIPECGETYHSDLAEAKKKKLAVGDNNSKWVKHWVKGGYYYYHNLETQEGGWDEPPNFVQNSMQLSREEIQSSISGVTAAYNREQLWLANEGLITRLQARCRGYLVRQEFRSRMNFLKKQIPAITCIQSQWRGYKQKKAYQDRLAYLRSHKDEVVKIQSLARMHQARKRYRDRLQYFRDHINDIIKIQAFIRANKARDDYKTLINAEDPPMVVVRKFVHLLDQSDQDFQEELDLMKMREEVITLIRSNQQLENDLNLMDIKIGLLVKNKITLQDVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFKTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALAHEEVKTRLDSSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFFQTACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESSGNLNDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRRAIRDAKTPDKMKKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKATFYGEQVDYYKSYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKFMGVQMETFMLHYQDLLQLQYEGVAVMKLFDRAKVNVNLLIFLLNKKFYGK 1066 17.6 1 50 50 26 26 0.778 0.619 0.558 33 35 30 * - * 0.651666667 0.113579634 tr|A4QPB0|A4QPB0_HUMAN 100 1.00E-112 gi|301015769|pdb|3I6X|A Chain A, Crystal Structure Of The Calponin Homology Domain Of Iqgap1 >gi|301015770|pdb|3I6X|B Chain B, Crystal Structure Of The Calponin Homology Domain Of Iqgap1 >gi|301015771|pdb|3I6X|C Chain C, Crystal Structure Of The Calponin Homology Domain Of Iqgap1 >gi|301015772|pdb|3I6X|D Chain D, Crystal Structure Of The Calponin Homology Domain Of Iqgap1 99.94 0 sp|P46940|IQGA1_HUMAN Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens GN=IQGAP1 PE=1 SV=1 100 5.00E-10 B4E2M0 B4E2M0_HUMAN cDNA FLJ55443, highly similar to Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens PE=2 SV=1 SPAC4F8.13c 385 2.00E-106 COG5261 Protein involved in regulation of cellular morphogenesis/cytokinesis DT Cell cycle control, cell division, chromosome partitioning ; Signal transduction mechanisms ; K05767|1|0.0|3365|hsa:8826|IQ motif containing GTPase activating protein GO:0071277//cellular response to calcium ion;GO:0072015//glomerular visceral epithelial cell development;GO:0006112//energy reserve metabolic process;GO:0050796//regulation of insulin secretion;GO:0001817//regulation of cytokine production;GO:0035305//negative regulation of dephosphorylation;GO:0007264//small GTPase mediated signal transduction;GO:0045860//positive regulation of protein kinase activity;GO:0043547//positive regulation of GTPase activity GO:0005095//GTPase inhibitor activity;GO:0019901//protein kinase binding;GO:0005509//calcium ion binding;GO:0019903//protein phosphatase binding;GO:0048365//Rac GTPase binding;GO:0005099//Ras GTPase activator activity;GO:0005516//calmodulin binding GO:0043005//neuron projection;GO:0005884//actin filament;GO:0036057//slit diaphragm;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005874//microtubule;GO:0031252//cell leading edge;GO:0016328//lateral plasma membrane;GO:0030496//midbody;GO:0030529//ribonucleoprotein complex 115 tr|A8K4K1|A8K4K1_HUMAN cDNA FLJ78216, highly similar to Homo sapiens lysosomal neuraminidase, mRNA OS=Homo sapiens PE=2 SV=1 49473 MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASGSKAENDFGLVQPLVTMEQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGSTWSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVSWSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASWRYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACDTLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKETVQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL 138 17.8 1 10 10 6 6 0.7 0.924 1.034 5 5 4 * - - 0.886 0.170211633 tr|A8K4K1|A8K4K1_HUMAN 100 3.00E-56 gi|47118726|gb|AAT11276.1| neurominidase precursor [Homo sapiens] 99.76 0 sp|Q5RAF4|NEUR1_PONAB Sialidase-1 OS=Pongo abelii GN=NEU1 PE=2 SV=1 100 1.00E-55 Q6Q4G8 Q6Q4G8_HUMAN Neurominidase (Fragment) OS=Homo sapiens GN=NEU1 PE=4 SV=1 Cgl1519 78.6 2.00E-14 COG4409 Neuraminidase (sialidase) G Carbohydrate transport and metabolism ; K01186|1|0.0|806|pon:100172668|sialidase-1 [EC:3.2.1.18] GO:0006687//glycosphingolipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0044281//small molecule metabolic process GO:0052795//exo-alpha-(2->6)-sialidase activity;GO:0052796//exo-alpha-(2->8)-sialidase activity;GO:0052794//exo-alpha-(2->3)-sialidase activity GO:0030054//cell junction;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane;GO:0043202//lysosomal lumen;GO:0005765//lysosomal membrane 116 tr|H7C3G9|H7C3G9_HUMAN N-acetyl-D-glucosamine kinase OS=Homo sapiens GN=NAGK PE=1 SV=2 41466 MAAIYGGVEGGGTRSEVLLVSEDGKILAEADGLSTNHWLIGTDKCVERINEMVNRAKRKAGVDPLVPLRSLGLSLSGGDQEDAGRILIEELRDRFPYLSESYLITTDAAGSIATATPDGGVVLISGTGSNCRLINPDGSESGCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHDIGYVKQAMFHYFQVPDRLGILTHLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGEMLGRHIVAVLPEIDPGKIGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFSSFTLMKLRHSSALGGASLGARHIGHLLPMDYSANAIAFYSYTFS 99 15 1 9 9 5 5 0.984 1.184 0.875 3 3 3 - - - 1.014333333 0.156717368 tr|H7C3G9|H7C3G9_HUMAN 98.84 0 gi|116666931|pdb|2CH5|A Chain A, Crystal Structure Of Human N-Acetylglucosamine Kinase In Complex With N-Acetylglucosamine >gi|116666932|pdb|2CH5|B Chain B, Crystal Structure Of Human N-Acetylglucosamine Kinase In Complex With N-Acetylglucosamine >gi|116666933|pdb|2CH5|C Chain C, Crystal Structure Of Human N-Acetylglucosamine Kinase In Complex With N-Acetylglucosamine >gi|116666934|pdb|2CH5|D Chain D, Crystal Structure Of Human N-Acetylglucosamine Kinase In Complex With N-Acetylglucosamine 98.84 0 sp|Q9UJ70|NAGK_HUMAN N-acetyl-D-glucosamine kinase OS=Homo sapiens GN=NAGK PE=1 SV=4 100 2.00E-49 E9PPU6 E9PPU6_HUMAN N-acetyl-D-glucosamine kinase OS=Homo sapiens GN=NAGK PE=4 SV=2 CAC0183 77 4.00E-14 COG2971 Predicted N-acetylglucosamine kinase G Carbohydrate transport and metabolism ; K00884|1|0.0|675|hsa:55577|N-acetylglucosamine kinase [EC:2.7.1.59] GO:0006051//N-acetylmannosamine metabolic process;GO:0006044//N-acetylglucosamine metabolic process GO:0005524//ATP binding;GO:0009384//N-acylmannosamine kinase activity;GO:0005515//protein binding;GO:0045127//N-acetylglucosamine kinase activity - 117 tr|B4DE91|B4DE91_HUMAN cDNA FLJ55534, highly similar to 4-trimethylaminobutyraldehyde dehydrogenase (EC 1.2.1.47) OS=Homo sapiens PE=2 SV=1 61861 MSTGTFVVSQPLNYRGGARVEPADASGRVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPGLFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESAF 67 2.9 4 2 2 1 1 0.797 0.837 1.843 2 2 2 - - - 1.159 0.592698912 tr|B4DE91|B4DE91_HUMAN 100 0 gi|194374213|dbj|BAG57002.1| unnamed protein product [Homo sapiens] 97.98 0 sp|P49189|AL9A1_HUMAN 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens GN=ALDH9A1 PE=1 SV=3 100 0 B4DX14 B4DX14_HUMAN cDNA FLJ53231, highly similar to 4-trimethylaminobutyraldehyde dehydrogenase(EC 1.2.1.47) OS=Homo sapiens PE=2 SV=1 ZbetB 497 2.00E-140 COG1012 NAD-dependent aldehyde dehydrogenases C Energy production and conversion ; K00149|1|0.0|954|hsa:223|aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3] GO:0055114//oxidation-reduction process;GO:0042445//hormone metabolic process;GO:0001889//liver development;GO:0045329//carnitine biosynthetic process;GO:0006081//cellular aldehyde metabolic process;GO:0001822//kidney development;GO:0042136//neurotransmitter biosynthetic process GO:0033737//1-pyrroline dehydrogenase activity;GO:0051287//NAD binding;GO:0043176//amine binding;GO:0004028//3-chloroallyl aldehyde dehydrogenase activity;GO:0019145//aminobutyraldehyde dehydrogenase activity;GO:0042803//protein homodimerization activity;GO:0047105//4-trimethylammoniobutyraldehyde dehydrogenase activity GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005886//plasma membrane 118 sp|O15031|PLXB2_HUMAN Plexin-B2 OS=Homo sapiens GN=PLXNB2 PE=1 SV=3 234504 MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGICALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNGIIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPARNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRDSRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGTFAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISVAGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIAEPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSLILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSKVGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEIYLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 104 1.8 - 5 5 3 3 1.213 1.723 1.375 2 2 2 - - - 1.437 0.260591635 sp|O15031|PLXB2_HUMAN 100 0 gi|2280476|dbj|BAA21571.1| KIAA0315 [Homo sapiens] 100 0 sp|O15031|PLXB2_HUMAN Plexin-B2 OS=Homo sapiens GN=PLXNB2 PE=1 SV=3 100 0 G2HF70 G2HF70_PANTR Plexin-B2 OS=Pan troglodytes PE=2 SV=1 - - - - - - - K06821|1|0.0|3697|hsa:23654|plexin B GO:0071526//semaphorin-plexin signaling pathway;GO:0008360//regulation of cell shape;GO:0007405//neuroblast proliferation;GO:0050772//positive regulation of axonogenesis;GO:0007420//brain development;GO:0001932//regulation of protein phosphorylation;GO:0001843//neural tube closure;GO:2001222//regulation of neuron migration;GO:0032319//regulation of Rho GTPase activity GO:0017154//semaphorin receptor activity;GO:0005515//protein binding;GO:0005096//GTPase activator activity GO:0005622//intracellular;GO:0005887//integral to plasma membrane 119 tr|B2R6J2|B2R6J2_HUMAN cDNA, FLJ92973, highly similar to Homo sapiens villin 2 (ezrin) (VIL2), mRNA OS=Homo sapiens PE=2 SV=1 86507 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELTQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL 421 14 4 53 5 8 2 0.912 0.947 0.804 4 4 4 - - - 0.887666667 0.074540817 tr|B2R6J2|B2R6J2_HUMAN 100 0 gi|189069151|dbj|BAG35489.1| unnamed protein product [Homo sapiens] 99.83 0 sp|P15311|EZRI_HUMAN Ezrin OS=Homo sapiens GN=EZR PE=1 SV=4 100 0 B2R6J2 B2R6J2_HUMAN cDNA, FLJ92973, highly similar to Homo sapiens villin 2 (ezrin) (VIL2), mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K08007|1|0.0|1076|ptr:463100|villin 2 (ezrin) GO:0007411//axon guidance;GO:0008360//regulation of cell shape;GO:0051017//actin filament bundle assembly;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0022614//membrane to membrane docking;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007159//leukocyte cell-cell adhesion;GO:0030855//epithelial cell differentiation GO:0050839//cell adhesion molecule binding;GO:0005198//structural molecule activity;GO:0051015//actin filament binding GO:0005925//focal adhesion;GO:0030863//cortical cytoskeleton;GO:0005884//actin filament;GO:0032587//ruffle membrane;GO:0030175//filopodium;GO:0031528//microvillus membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0019898//extrinsic to membrane;GO:0001931//uropod;GO:0005932//microtubule basal body;GO:0016324//apical plasma membrane 120 tr|A8K2Q6|A8K2Q6_HUMAN Peptidyl-prolyl cis-trans isomerase OS=Homo sapiens PE=2 SV=1 27988 MGPGPRLLLPLVLCVGLGALVFSSGAEGFRKRGPSVTAKVFFDVRIGDKDVGRIVIGLFGKVVPKTVENFVALATGEKGYGYKGSKFHRVIKDFMIQGGDITTGDGTGGVSIYGETFPDENFKLKHYGIGWVSLANAGPDTNGSQFFITLTKPTWLDGKHVVFGKVIDGMTVAHSIELQATDGHDRPLTNCSIINSGKIDVKTPFVVEIADW 171 12.7 1 11 11 3 3 0.566 1.156 1.093 6 6 6 - - - 0.938333333 0.323985082 tr|A8K2Q6|A8K2Q6_HUMAN 100 1.00E-97 gi|158261665|dbj|BAF83010.1| unnamed protein product [Homo sapiens] 98.95 1.00E-97 sp|P45877|PPIC_HUMAN Peptidyl-prolyl cis-trans isomerase C OS=Homo sapiens GN=PPIC PE=1 SV=1 100 4.00E-97 A8K2Q6 A8K2Q6_HUMAN Peptidyl-prolyl cis-trans isomerase OS=Homo sapiens PE=2 SV=1 YHR057c 186 2.00E-47 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family O Posttranslational modification, protein turnover, chaperones ; K09563|1|1e-97|355|hsa:5480|peptidyl-prolyl isomerase C (cyclophilin C) [EC:5.2.1.8] GO:0006457//protein folding;GO:0007165//signal transduction GO:0016018//cyclosporin A binding;GO:0051082//unfolded protein binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity GO:0005737//cytoplasm 121 sp|O14907|TX1B3_HUMAN Tax1-binding protein 3 OS=Homo sapiens GN=TAX1BP3 PE=1 SV=2 16160 MSYIPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQSMLS 113 13.7 - 4 4 1 1 0.723 1.114 0.722 2 2 2 - - - 0.853 0.226033183 sp|O14907|TX1B3_HUMAN 100 1.00E-65 gi|284055340|pdb|2KG2|A Chain A, Solution Structure Of A Pdz Protein 100 2.00E-67 sp|O14907|TX1B3_HUMAN Tax1-binding protein 3 OS=Homo sapiens GN=TAX1BP3 PE=1 SV=2 100 9.00E-66 G5B935 G5B935_HETGA Tax1-binding protein 3 OS=Heterocephalus glaber GN=GW7_14607 PE=4 SV=1 - - - - - - - K08876|1|1e-14|78.6|tsp:Tsp_08308|SCY1-like!K15682|2|4e-11|66.6|gga:417787|ligand of Numb protein X 3/4 GO:0032864//activation of Cdc42 GTPase activity;GO:0060028//convergent extension involved in axis elongation;GO:0008285//negative regulation of cell proliferation;GO:0030178//negative regulation of Wnt receptor signaling pathway;GO:2000009//negative regulation of protein localization to cell surface GO:0008022//protein C-terminus binding;GO:0008013//beta-catenin binding GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005634//nucleus 122 tr|A0AVL1|A0AVL1_HUMAN ADAM9 protein OS=Homo sapiens GN=ADAM9 PE=2 SV=1 93412 MGSGARFPSGTLRVRWLLLLGLVGPVLGAARPGFQQTSHLSSYEIITPWRLTRERREAPRPYSKQVSYVIQAEGKEHIIHLERNKDLLPEDFVVYTYNKEGTLITDHPNIQNHCHYRGYVEGVHNSSIALSDCFGLRGLLHLENASYGIEPLQNSSHFEHIIYRMDDVYKEPLKCGVSNKDIEKETAKDEEEEPPSMTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMILLANYLDSMYIMLNIRIVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRHDSAQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDGRDCSCGAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPSCGNKLVDAGEECDCGTPKECELDPCCEGSTCKLKSFAECAYGDCCKDCRFLPGGTLCRGKTSECDVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKDCFIEVNSKGDRFGNCGFSGNEYKKCATGNALCGKLQCENVQEIPVFGIVPAIIQTPSRGTKCWGVDFQLGSDVPDPGMVNEGTKCGAGKICRNFQCVDASVLNYDCDVQKKCHGHGVCNSNKNCHCENGWAPPNCETKGYGGSVDSGPTYNGQMAKIKQTLLDSRGVFLDMFLQ 108 6.3 2 10 10 4 4 0.836 0.501 0.88 7 6 7 - * - 0.739 0.207284828 tr|A0AVL1|A0AVL1_HUMAN 100 0 gi|21359696|gb|AAM49575.1|AF495383_1 disintegrin/metalloproteinase domain 9 short protein precursor [Homo sapiens] >gi|119583688|gb|EAW63284.1| ADAM metallopeptidase domain 9 (meltrin gamma), isoform CRA_b [Homo sapiens] >gi|219519478|gb|AAI43924.1| ADAM metallopeptidase domain 9 (meltrin gamma) [Homo sapiens] 98.71 0 sp|Q13443|ADAM9_HUMAN Disintegrin and metalloproteinase domain-containing protein 9 OS=Homo sapiens GN=ADAM9 PE=1 SV=1 100 0 A0AVL1 A0AVL1_HUMAN ADAM9 protein OS=Homo sapiens GN=ADAM9 PE=2 SV=1 - - - - - - - K06834|1|0.0|1392|pon:100462489|disintegrin and metalloproteinase domain-containing protein 9 [EC:3.4.24.-] GO:0010042//response to manganese ion;GO:0042117//monocyte activation;GO:0042542//response to hydrogen peroxide;GO:0007160//cell-matrix adhesion;GO:0000186//activation of MAPKK activity;GO:0034241//positive regulation of macrophage fusion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0051592//response to calcium ion;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0007229//integrin-mediated signaling pathway;GO:0051384//response to glucocorticoid stimulus;GO:0050714//positive regulation of protein secretion;GO:0034612//response to tumor necrosis factor;GO:0033631//cell-cell adhesion mediated by integrin;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0030216//keratinocyte differentiation;GO:0071222//cellular response to lipopolysaccharide;GO:0051549//positive regulation of keratinocyte migration;GO:0051088//PMA-inducible membrane protein ectodomain proteolysis GO:0005178//integrin binding;GO:0005080//protein kinase C binding;GO:0043236//laminin binding;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity;GO:0005518//collagen binding;GO:0017124//SH3 domain binding GO:0031233//intrinsic to external side of plasma membrane;GO:0005615//extracellular space;GO:0016021//integral to membrane;GO:0005737//cytoplasm 123 tr|Q05DH1|Q05DH1_HUMAN Proteasome subunit alpha type (Fragment) OS=Homo sapiens GN=PSMA7 PE=2 SV=1 33256 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKKKKK 153 13 1 10 10 4 4 0.995 0.852 0.894 6 6 6 - - * 0.913666667 0.073500567 tr|Q05DH1|Q05DH1_HUMAN 100 1.00E-88 gi|117558331|gb|AAI27467.1| Psma7 protein [Rattus norvegicus] 100 4.00E-129 sp|O14818|PSA7_HUMAN Proteasome subunit alpha type-7 OS=Homo sapiens GN=PSMA7 PE=1 SV=1 100 3.00E-127 Q05DH1 Q05DH1_HUMAN Proteasome subunit alpha type (Fragment) OS=Homo sapiens GN=PSMA7 PE=2 SV=1 AF0490 211 6.00E-55 COG0638 20S proteasome, alpha and beta subunits O Posttranslational modification, protein turnover, chaperones ; K02731|1|4e-129|460|hsa:5688|20S proteasome subunit alpha 4 [EC:3.4.25.1] GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0019048//virus-host interaction;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0004298//threonine-type endopeptidase activity;GO:0042802//identical protein binding GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0019773//proteasome core complex, alpha-subunit complex 124 tr|J3KRE2|J3KRE2_HUMAN Rho GDP-dissociation inhibitor 1 OS=Homo sapiens GN=ARHGDIA PE=1 SV=1 18760 MAEQEPTAEQLAQIAAENEEDEHSVNYKPPAQKSIQEIQELDKDDESLRKYKEALLGRVAVSAVDKTDYMVGSYGPRAEEYEFLTPVEEAPKGMLARGSYSIKSRFTDDDKTDHLSWEWNLTIKKDWKD 144 24 3 9 9 2 2 0.749 1.022 0.614 6 6 6 - - * 0.795 0.207853314 tr|J3KRE2|J3KRE2_HUMAN 100 1.00E-27 gi|4757768|ref|NP_004300.1| rho GDP-dissociation inhibitor 1 isoform a [Homo sapiens] >gi|297374782|ref|NP_001172006.1| rho GDP-dissociation inhibitor 1 isoform a [Homo sapiens] >gi|350535254|ref|NP_001233363.1| rho GDP-dissociation inhibitor 1 [Pan troglodytes] >gi|1707892|sp|P52565.3|GDIR1_HUMAN RecName: Full=Rho GDP-dissociation inhibitor 1; Short=Rho GDI 1; AltName: Full=Rho-GDI alpha >gi|75075715|sp|Q4R4J0.1|GDIR1_MACFA RecName: Full=Rho GDP-dissociation inhibitor 1; Short=Rho GDI 1; AltName: Full=Rho-GDI alpha >gi|6980758|pdb|1CC0|E Chain E, Crystal Structure Of The Rhoa.Gdp-Rhogdi Complex >gi|6980760|pdb|1CC0|F Chain F, Crystal Structure Of The Rhoa.Gdp-Rhogdi Complex >gi|15826632|pdb|1HH4|D Chain D, Rac1-Rhogdi Complex Involved In Nadph Oxidase Activation >gi|15826633|pdb|1HH4|E Chain E, Rac1-Rhogdi Complex Involved In Nadph Oxidase Activation >gi|20379028|gb|AAM21074.1|AF498926_1 Rho GDP dissociation inhibitor alpha [Homo sapiens] >gi|285979|dbj|BAA03096.1| human rho GDI [Homo sapiens] >gi|337395|gb|AAA36566.1| GDP dissociation inhibitor [Homo sapiens] >gi|456191|emb|CAA49281.1| Human rho GDP-dissociation Inhibitor 1(IEF 8118) [Homo sapiens] >gi|13543381|gb|AAH05851.1| Rho GDP dissociation inhibitor (GDI) alpha [Homo sapiens] >gi|13543436|gb|AAH05875.1| Rho GDP dissociation inhibitor (GDI) alpha [Homo sapiens] >gi|14250508|gb|AAH08701.1| Rho GDP dissociation inhibitor (GDI) alpha [Homo sapiens] >gi|14602503|gb|AAH09759.1| Rho GDP dissociation inhibitor (GDI) alpha [Homo sapiens] >gi|16359132|gb|AAH16031.1| Rho GDP dissociation inhibitor (GDI) alpha [Homo sapiens] >gi|16740603|gb|AAH16185.1| Rho GDP dissociation inhibitor (GDI) alpha [Homo sapiens] >gi|18999474|gb|AAH24258.1| Rho GDP dissociation inhibitor (GDI) alpha [Homo sapiens] >gi|20380701|gb|AAH27730.1| Rho GDP dissociation inhibitor (GDI) alpha [Homo sapiens] >gi|30582607|gb|AAP35530.1| Rho GDP dissociation inhibitor (GDI) alpha [Homo sapiens] >gi|48145671|emb|CAG33058.1| ARHGDIA [Homo sapiens] >gi|49899246|gb|AAH75827.1| Rho GDP dissociation inhibitor (GDI) alpha [Homo sapiens] >gi|76780069|gb|AAI06045.1| Rho GDP dissociation inhibitor (GDI) alpha [Homo sapiens] >gi|119610103|gb|EAW89697.1| Rho GDP dissociation inhibitor (GDI) alpha, isoform CRA_a [Homo sapiens] >gi|119610104|gb|EAW89698.1| Rho GDP dissociation inhibitor (GDI) alpha, isoform CRA_a [Homo sapiens] >gi|343958932|dbj|BAK63321.1| Rho GDP-dissociation inhibitor 1 [Pan troglodytes] 100 1.00E-28 sp|Q4R4J0|GDIR1_MACFA Rho GDP-dissociation inhibitor 1 OS=Macaca fascicularis GN=ARHGDIA PE=2 SV=1 100 1.00E-27 G1RH56 G1RH56_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=ARHGDIA PE=4 SV=1 - - - - - - - K12462|1|1e-60|231|ptr:454971|Rho GDP-dissociation inhibitor GO:0007266//Rho protein signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0050771//negative regulation of axonogenesis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0006928//cellular component movement;GO:0007162//negative regulation of cell adhesion;GO:0050772//positive regulation of axonogenesis;GO:0032880//regulation of protein localization;GO:0043547//positive regulation of GTPase activity GO:0005515//protein binding;GO:0005094//Rho GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity GO:0001772//immunological synapse;GO:0005829//cytosol;GO:0005856//cytoskeleton 125 sp|P08254|MMP3_HUMAN Stromelysin-1 OS=Homo sapiens GN=MMP3 PE=1 SV=2 64571 MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAVSTLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC 570 21.2 - 65 51 11 9 2.268 2.245 2.901 18 18 18 * - - 2.471333333 0.372279913 sp|P08254|MMP3_HUMAN 100 0 gi|4505217|ref|NP_002413.1| stromelysin-1 preproprotein [Homo sapiens] >gi|116857|sp|P08254.2|MMP3_HUMAN RecName: Full=Stromelysin-1; Short=SL-1; AltName: Full=Matrix metalloproteinase-3; Short=MMP-3; AltName: Full=Transin-1; Flags: Precursor >gi|15294140|gb|AAK95247.1|AF405705_1 matrix metalloproteinase 3 (stromelysin 1, progelatinase) [Homo sapiens] >gi|36633|emb|CAA28859.1| preprostromelysin [Homo sapiens] >gi|50960572|gb|AAH74815.1| Matrix metalloproteinase 3, preproprotein [Homo sapiens] >gi|77567646|gb|AAI07492.1| Matrix metalloproteinase 3, preproprotein [Homo sapiens] >gi|119587436|gb|EAW67032.1| matrix metallopeptidase 3 (stromelysin 1, progelatinase) [Homo sapiens] 100 0 sp|P08254|MMP3_HUMAN Stromelysin-1 OS=Homo sapiens GN=MMP3 PE=1 SV=2 98.74 0 H2Q4N2 H2Q4N2_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000149968 PE=4 SV=1 - - - - - - - K01394|1|0.0|920|hsa:4314|matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17] GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0030334//regulation of cell migration;GO:0071230//cellular response to amino acid stimulus;GO:0030574//collagen catabolic process GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0004222//metalloendopeptidase activity GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 126 tr|Q7Z7M4|Q7Z7M4_HUMAN Superoxide dismutase (Fragment) OS=Homo sapiens GN=SOD2 PE=2 SV=1 28031 AVCGTSRQLAPALGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERY 633 16.9 1 24 24 3 3 2.08 1.894 1.81 24 23 22 * * * 1.928 0.138173804 tr|Q7Z7M4|Q7Z7M4_HUMAN 100 6.00E-97 gi|193783553|dbj|BAG53464.1| unnamed protein product [Homo sapiens] 100 4.00E-124 sp|P04179|SODM_HUMAN Superoxide dismutase [Mn], mitochondrial OS=Homo sapiens GN=SOD2 PE=1 SV=2 100 3.00E-122 Q7Z7M4 Q7Z7M4_HUMAN Superoxide dismutase (Fragment) OS=Homo sapiens GN=SOD2 PE=2 SV=1 CT294 229 3.00E-60 COG0605 Superoxide dismutase P Inorganic ion transport and metabolism ; K04564|1|2e-123|441|hsa:6648|superoxide dismutase, Fe-Mn family [EC:1.15.1.1] GO:0043524//negative regulation of neuron apoptotic process;GO:0032364//oxygen homeostasis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030097//hemopoiesis;GO:0034021//response to silicon dioxide;GO:0051289//protein homotetramerization;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0042542//response to hydrogen peroxide;GO:0010332//response to gamma radiation;GO:0007507//heart development;GO:0010269//response to selenium ion;GO:0051602//response to electrical stimulus;GO:0042554//superoxide anion generation;GO:0051881//regulation of mitochondrial membrane potential;GO:0006749//glutathione metabolic process;GO:0009791//post-embryonic development;GO:0001889//liver development;GO:0001315//age-dependent response to reactive oxygen species;GO:0001666//response to hypoxia;GO:0010043//response to zinc ion;GO:0050665//hydrogen peroxide biosynthetic process;GO:0019430//removal of superoxide radicals;GO:0071361//cellular response to ethanol;GO:0010042//response to manganese ion;GO:0007626//locomotory behavior;GO:0050790//regulation of catalytic activity;GO:0033591//response to L-ascorbic acid;GO:0022904//respiratory electron transport chain;GO:0014823//response to activity;GO:0048666//neuron development;GO:0055072//iron ion homeostasis;GO:0048773//erythrophore differentiation;GO:0055093//response to hyperoxia;GO:0003032//detection of oxygen;GO:0045599//negative regulation of fat cell differentiation;GO:0003069//vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure;GO:0001836//release of cytochrome c from mitochondria;GO:0046686//response to cadmium ion;GO:0042493//response to drug;GO:0048147//negative regulation of fibroblast proliferation;GO:0032496//response to lipopolysaccharide;GO:0048678//response to axon injury GO:0030145//manganese ion binding;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0004784//superoxide dismutase activity;GO:0019825//oxygen binding GO:0042645//mitochondrial nucleoid;GO:0005743//mitochondrial inner membrane 127 tr|Q59EG8|Q59EG8_HUMAN Proteasome 26S non-ATPase subunit 2 variant (Fragment) OS=Homo sapiens PE=2 SV=1 117141 AVAAEMEEGGRDKAPVQPQQSPAAAPGGTDEKPSGKERRDAGDKDKEQELSEEDKQLQDELEMLVERLGEKDTSLYRPALEELRRQIRSSTTSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKRFAADIISVLAMTMSGERECLKYRLVGSQEELASWGHEYVRHLAGEVAKEWQELDDAEKVQREPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYVPEPENSALLCCALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGRHGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGGSGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRNECDPALALLSDYVLHNSNTMRLGSIFGLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTALACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKKEAPADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGKGTLTLCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPLPVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVILRKNPNYDL 313 4.9 1 11 11 4 4 0.836 0.615 0.73 6 6 4 - * - 0.727 0.110530539 tr|Q59EG8|Q59EG8_HUMAN 100 0 gi|67968534|dbj|BAE00628.1| unnamed protein product [Macaca fascicularis] 99.89 0 sp|Q13200|PSMD2_HUMAN 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens GN=PSMD2 PE=1 SV=3 100 0 Q4R8E4 Q4R8E4_MACFA Testis cDNA clone: QtsA-12648, similar to human proteasome (prosome, macropain) 26S subunit, non-ATPase,2 (PSMD2), OS=Macaca fascicularis PE=2 SV=1 SPBP19A11.03c 857 0 COG5110 26S proteasome regulatory complex component O Posttranslational modification, protein turnover, chaperones ; K03028|1|0.0|1672|pon:100172819|26S proteasome regulatory subunit N1 GO:0000209//protein polyubiquitination;GO:0042176//regulation of protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0016032//viral reproduction;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0005515//protein binding;GO:0030234//enzyme regulator activity GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle 128 tr|B4DX19|B4DX19_HUMAN cDNA FLJ57644, highly similar to Serum paraoxonase/arylesterase 1 (EC 3.1.1.2) OS=Homo sapiens PE=2 SV=1 45951 MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELETGSEDMEILPNGLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTFTDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYGTNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPPASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL 356 5.6 1 19 19 2 2 0.894 1.029 0.959 2 2 2 - - - 0.960666667 0.06751543 tr|B4DX19|B4DX19_HUMAN 100 0 gi|194377736|dbj|BAG63231.1| unnamed protein product [Homo sapiens] 95.5 0 sp|P27169|PON1_HUMAN Serum paraoxonase/arylesterase 1 OS=Homo sapiens GN=PON1 PE=1 SV=3 100 1.00E-12 Q96P89 Q96P89_HUMAN Paraoxonase 1 (Fragment) OS=Homo sapiens GN=PON1 PE=2 SV=1 - - - - - - - K01045|1|0.0|659|hsa:5444|arylesterase / paraoxonase [EC:3.1.1.2 3.1.8.1] GO:0010875//positive regulation of cholesterol efflux;GO:0034445//negative regulation of plasma lipoprotein particle oxidation;GO:0046395//carboxylic acid catabolic process;GO:0019439//aromatic compound catabolic process;GO:0009636//response to toxic substance;GO:0051099//positive regulation of binding;GO:0046470//phosphatidylcholine metabolic process;GO:0032411//positive regulation of transporter activity;GO:0046434//organophosphate catabolic process;GO:0009605//response to external stimulus GO:0004063//aryldialkylphosphatase activity;GO:0005509//calcium ion binding;GO:0005543//phospholipid binding;GO:0004064//arylesterase activity;GO:0042803//protein homodimerization activity GO:0034366//spherical high-density lipoprotein particle 129 sp|P67936|TPM4_HUMAN Tropomyosin alpha-4 chain OS=Homo sapiens GN=TPM4 PE=1 SV=3 >tr|V9HW56|V9HW56_HUMAN Epididymis secretory protein Li 108 OS=Homo sapiens GN=HEL-S-108 PE=2 SV=1 36528 MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 1873 18.5 - 113 6 6 1 0.544 0.494 0.66 6 6 6 * * * 0.566 0.085158675 sp|P67936|TPM4_HUMAN 100 1.00E-59 gi|334326964|ref|XP_003340817.1| PREDICTED: tropomyosin alpha-4 chain-like isoform 1 [Monodelphis domestica] >gi|395513661|ref|XP_003761041.1| PREDICTED: tropomyosin alpha-1 chain isoform 1 [Sarcophilus harrisii] 100 1.00E-75 sp|P67936|TPM4_HUMAN Tropomyosin alpha-4 chain OS=Homo sapiens GN=TPM4 PE=1 SV=3 100 4.00E-74 E2R662 E2R662_CANFA Uncharacterized protein OS=Canis familiaris GN=TPM4 PE=3 SV=1 - - - - - - - K10375|1|2e-75|282|ptr:100612873|tropomyosin 4 GO:0006979//response to oxidative stress;GO:0030049//muscle filament sliding;GO:0055003//cardiac myofibril assembly;GO:0060048//cardiac muscle contraction GO:0008307//structural constituent of muscle;GO:0046872//metal ion binding GO:0005829//cytosol;GO:0030863//cortical cytoskeleton;GO:0002102//podosome;GO:0001725//stress fiber;GO:0005862//muscle thin filament tropomyosin;GO:0031941//filamentous actin 130 tr|W8QEH3|W8QEH3_HUMAN Lamin A/C OS=Homo sapiens GN=LMNA PE=3 SV=1 77303 METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAIRKLVRSVTVVEDDEDEDGDDLLHHHHVSGSRR 1478 30.8 1 79 79 14 14 1.475 1.375 1.717 53 53 54 - * * 1.522333333 0.175844628 tr|W8QEH3|W8QEH3_HUMAN 100 0 gi|119573385|gb|EAW53000.1| lamin A/C, isoform CRA_d [Homo sapiens] 99.82 0 sp|P02545|LMNA_HUMAN Prelamin-A/C OS=Homo sapiens GN=LMNA PE=1 SV=1 100 8.00E-13 E9PSR1 E9PSR1_RAT Prelamin-A/C OS=Rattus norvegicus GN=Lmna PE=3 SV=1 - - - - - - - K12641|1|0.0|878|hsa:4000|lamin A/C GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0042981//regulation of apoptotic process;GO:0055015//ventricular cardiac muscle cell development;GO:0030334//regulation of cell migration;GO:0007283//spermatogenesis;GO:0007517//muscle organ development;GO:0090343//positive regulation of cell aging;GO:0006998//nuclear envelope organization;GO:0030951//establishment or maintenance of microtubule cytoskeleton polarity;GO:0071456//cellular response to hypoxia;GO:0035105//sterol regulatory element binding protein import into nucleus;GO:0006987//activation of signaling protein activity involved in unfolded protein response GO:0005198//structural molecule activity;GO:0005515//protein binding GO:0005654//nucleoplasm;GO:0005638//lamin filament;GO:0005635//nuclear envelope;GO:0016363//nuclear matrix;GO:0048471//perinuclear region of cytoplasm 131 sp|P46109|CRKL_HUMAN Crk-like protein OS=Homo sapiens GN=CRKL PE=1 SV=1 38433 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE 65 11.9 - 3 3 3 3 0.782 1.24 0.909 2 2 2 - - - 0.977 0.236450841 sp|P46109|CRKL_HUMAN 100 1.00E-37 gi|159164076|pdb|2DBK|A Chain A, Solution Structures Of The Sh3 Domain Of Human Crk-Like Protein 100 3.00E-172 sp|P46109|CRKL_HUMAN Crk-like protein OS=Homo sapiens GN=CRKL PE=1 SV=1 100 7.00E-171 G7PHA6 G7PHA6_MACFA Putative uncharacterized protein OS=Macaca fascicularis GN=EGM_02470 PE=4 SV=1 - - - - - - - K04438|1|3e-172|604|mcc:696584|proto-oncogene C-crk GO:0009887//organ morphogenesis;GO:0060017//parathyroid gland development;GO:0001568//blood vessel development;GO:0007254//JNK cascade;GO:0048538//thymus development;GO:0009952//anterior/posterior pattern specification;GO:0007507//heart development;GO:0007265//Ras protein signal transduction GO:0005070//SH3/SH2 adaptor activity;GO:0004871//signal transducer activity GO:0005829//cytosol 132 tr|Q2TU64|Q2TU64_HUMAN T-complex protein 1 subunit gamma OS=Homo sapiens PE=2 SV=1 72366 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGNVMTNDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMWRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDIGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPDAGQE 113 5.9 4 5 5 3 3 0.96 0.452 0.628 3 3 4 - * - 0.68 0.257961237 tr|Q2TU64|Q2TU64_HUMAN 100 3.00E-114 gi|609308|gb|AAC50068.1| cytoplasmic chaperonin hTRiC5, partial [Homo sapiens] 99.45 0 sp|P49368|TCPG_HUMAN T-complex protein 1 subunit gamma OS=Homo sapiens GN=CCT3 PE=1 SV=4 100 0 Q2TU64 Q2TU64_HUMAN PIG48 OS=Homo sapiens PE=2 SV=1 SPBC1A4.08c 716 0 COG0459 Chaperonin GroEL (HSP60 family) O Posttranslational modification, protein turnover, chaperones ; K09495|1|0.0|1106|pon:100172920|T-complex protein 1 subunit gamma GO:0051084//'de novo' posttranslational protein folding GO:0005524//ATP binding;GO:0051082//unfolded protein binding GO:0005832//chaperonin-containing T-complex;GO:0005886//plasma membrane;GO:0005874//microtubule 133 sp|Q9UNA0|ATS5_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 5 OS=Homo sapiens GN=ADAMTS5 PE=1 SV=2 122300 MLLGWASLLLCAFRLPLAAVGPAATPAQDKAGQPPTAAAAAQPRRRQGEEVQERAEPPGHPHPLAQRRRSKGLVQNIDQLYSGGGKVGYLVYAGGRRFLLDLERDGSVGIAGFVPAGGGTSAPWRHRSHCFYRGTVDGSPRSLAVFDLCGGLDGFFAVKHARYTLKPLLRGPWAEEEKGRVYGDGSARILHVYTREGFSFEALPPRASCETPASTPEAHEHAPAHSNPSGRAALASQLLDQSALSPAGGSGPQTWWRRRRRSISRARQVELLLVADASMARLYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSHDDSKFCEETFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQILGPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRLYSNSVCVRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSCTKIVGTFNKKSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLAKGCPLSQRPSAFKQCLLKKC 79 1.6 - 2 2 1 1 1.64 1.534 0.56 2 2 2 - - - 1.244666667 0.595302724 sp|Q9UNA0|ATS5_HUMAN 100 0 gi|162330137|pdb|2RJQ|A Chain A, Crystal Structure Of Adamts5 With Inhibitor Bound 100 0 sp|Q9UNA0|ATS5_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 5 OS=Homo sapiens GN=ADAMTS5 PE=1 SV=2 99.68 0 H2QKW1 H2QKW1_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000154736 PE=4 SV=1 - - - - - - - K08620|1|0.0|1740|hsa:11096|a disintegrin and metalloproteinase with thrombospondin motifs 5 [EC:3.4.24.-] GO:0006508//proteolysis GO:0004222//metalloendopeptidase activity;GO:0005178//integrin binding;GO:0008270//zinc ion binding GO:0005578//proteinaceous extracellular matrix 134 tr|B4DGN8|B4DGN8_HUMAN cDNA FLJ53377, highly similar to Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) OS=Homo sapiens PE=2 SV=1 90567 MRPLLLLALLGWLLLAEAKGDAKPEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWNVEKGTSAGGGQKVRLLKKALEKHADKEELIYPDRRLETKYPVVSDGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKREQINITLDHRCRIFQNLDGALDEVVLKFEMGHVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTFETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFVSLFFQRLLRLHYPQKHMRLFIHNHEQHHKAQVEEFLAQHGSEYQSVKLVGPEVRMANADARNMGADLCRQYRSCTYYFSVDADVALTEPNSLRLLIQQNKNVIAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRGELQSSDLFHHSKLDPDMAFCANIRQQDVFMFLTNRHTLGHLLSLDSYRTTHLHNDLWEVFSNPEDWKEKYIHQNYTKALAGKLVETPCPDVYWFPIFTEVACDELVEEMEHFGQWSLGNNKDNRIQGGYENVPTIDIHMNQIGFEREWHKFLLEYIAPMTEKLYPGYYTRAQFDLAFVVRYKPDEQPSLMPHHDASTFTINIALNRVGVDYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTRGTRYIAVSFVDP 979 24.9 2 39 39 13 13 0.901 0.567 0.819 27 28 26 - - * 0.762333333 0.174061292 tr|B4DGN8|B4DGN8_HUMAN 100 0 gi|194378198|dbj|BAG57849.1| unnamed protein product [Homo sapiens] 94.77 0 sp|Q02809|PLOD1_HUMAN Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Homo sapiens GN=PLOD1 PE=1 SV=2 100 0 B4DGN8 B4DGN8_HUMAN cDNA FLJ53377, highly similar to Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) OS=Homo sapiens PE=2 SV=1 - - - - - - - K00473|1|0.0|1387|hsa:5351|procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 [EC:1.14.11.4] GO:0001666//response to hypoxia;GO:0055114//oxidation-reduction process;GO:0008544//epidermis development;GO:0006464//cellular protein modification process;GO:0030198//extracellular matrix organization;GO:0046947//hydroxylysine biosynthetic process GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0008475//procollagen-lysine 5-dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0042803//protein homodimerization activity;GO:0005506//iron ion binding GO:0005581//collagen;GO:0030867//rough endoplasmic reticulum membrane 135 tr|A0A087WZH7|A0A087WZH7_HUMAN Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens GN=MARCKS PE=1 SV=1 40513 MGAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPARPRSGGSPRGGARGRRSLVSAAPSQEAQPECSPEAPPAEAAE 97 5.5 2 4 4 1 1 --- 1.293 0.97 1 3 3 - - - 1.1315 0.22839549 tr|A0A087WZH7|A0A087WZH7_HUMAN 100 4.00E-15 gi|332213069|ref|XP_003255641.1| PREDICTED: LOW QUALITY PROTEIN: myristoylated alanine-rich C-kinase substrate [Nomascus leucogenys] 100 5.00E-16 sp|P29966|MARCS_HUMAN Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens GN=MARCKS PE=1 SV=4 100 1.00E-14 F7I176 F7I176_CALJA Uncharacterized protein OS=Callithrix jacchus GN=LOC100400860 PE=4 SV=1 - - - - - - - K12561|1|4e-16|85.9|pon:100445187|myristoylated alanine-rich C-kinase substrate GO:0050796//regulation of insulin secretion;GO:0006112//energy reserve metabolic process;GO:0044281//small molecule metabolic process GO:0005080//protein kinase C binding;GO:0051015//actin filament binding GO:0042585//germinal vesicle;GO:0005813//centrosome;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane 136 sp|O95965|ITGBL_HUMAN Integrin beta-like protein 1 OS=Homo sapiens GN=ITGBL1 PE=2 SV=1 >tr|A0A024RDW7|A0A024RDW7_HUMAN Integrin, beta-like 1 (With EGF-like repeat domains), isoform CRA_a OS=Homo sapiens GN=ITGBL1 PE=4 SV=1 66963 MRPPGFRNFLLLASSLLFAGLSAVPQSFSPSLRSWPGAACRLSRAESERRCRAPGQPPGAALCHGRGRCDCGVCICHVTEPGMFFGPLCECHEWVCETYDGSTCAGHGKCDCGKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGDRRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGKLCQHPRKCNMTEEQSKNLCESADGILCSGKGSCHCGKCICSAEEWYISGEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGWNGNACEIWLGSEYP 716 35 - 33 33 11 11 1.859 1.82 1.709 25 25 24 * * * 1.796 0.077826731 sp|O95965|ITGBL_HUMAN 100 3.00E-176 gi|418203907|ref|NP_001258685.1| integrin beta-like protein 1 isoform 3 [Homo sapiens] 100 0 sp|O95965|ITGBL_HUMAN Integrin beta-like protein 1 OS=Homo sapiens GN=ITGBL1 PE=2 SV=1 100 5.00E-176 F5GZX0 F5GZX0_HUMAN Integrin beta-like protein 1 OS=Homo sapiens GN=ITGBL1 PE=4 SV=1 - - - - - - - K06493|1|4e-22|106|ecb:100009709|integrin beta 3 GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway GO:0004872//receptor activity;GO:0005102//receptor binding GO:0005576//extracellular region;GO:0008305//integrin complex 137 sp|Q9Y266|NUDC_HUMAN Nuclear migration protein nudC OS=Homo sapiens GN=NUDC PE=1 SV=1 48923 MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKVVTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMDQHPEMDFSKAKFN 79 8.2 1 3 3 2 2 0.951 1.048 0.819 3 3 3 - - - 0.939333333 0.114944914 sp|Q9Y266|NUDC_HUMAN 100 9.00E-162 gi|5729953|ref|NP_006591.1| nuclear migration protein nudC [Homo sapiens] >gi|62287138|sp|Q9Y266.1|NUDC_HUMAN RecName: Full=Nuclear migration protein nudC; AltName: Full=Nuclear distribution protein C homolog >gi|4836670|gb|AAD30517.1|AF130736_1 nuclear distribution protein C homolog [Homo sapiens] >gi|5107004|gb|AAD39921.1|AF125465_1 nuclear distribution protein [Homo sapiens] >gi|33150548|gb|AAP97152.1|AF086922_1 SIG-92 [Homo sapiens] >gi|5410306|gb|AAD43024.1| MNUDC protein [Homo sapiens] >gi|12803187|gb|AAH02399.1| Nuclear distribution gene C homolog (A. nidulans) [Homo sapiens] >gi|13111923|gb|AAH03132.1| Nuclear distribution gene C homolog (A. nidulans) [Homo sapiens] >gi|13544023|gb|AAH06147.1| Nuclear distribution gene C homolog (A. nidulans) [Homo sapiens] >gi|13938303|gb|AAH07280.1| Nuclear distribution gene C homolog (A. nidulans) [Homo sapiens] >gi|15929442|gb|AAH15153.1| Nuclear distribution gene C homolog (A. nidulans) [Homo sapiens] >gi|18088935|gb|AAH21139.1| Nuclear distribution gene C homolog (A. nidulans) [Homo sapiens] >gi|119628185|gb|EAX07780.1| nuclear distribution gene C homolog (A. nidulans) [Homo sapiens] 100 1.00E-162 sp|Q9Y266|NUDC_HUMAN Nuclear migration protein nudC OS=Homo sapiens GN=NUDC PE=1 SV=1 100 5.00E-87 Q9H2R7 Q9H2R7_HUMAN NPD011 OS=Homo sapiens GN=NUDC PE=2 SV=1 - - - - - - - - GO:0000236//mitotic prometaphase;GO:0007097//nuclear migration;GO:0008283//cell proliferation;GO:0043434//response to peptide hormone stimulus;GO:0007275//multicellular organismal development;GO:0000910//cytokinesis - GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005874//microtubule 138 tr|Q0QEN7|Q0QEN7_HUMAN ATP synthase subunit beta (Fragment) OS=Homo sapiens GN=ATP5B PE=2 SV=1 54471 AVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFMEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHMGKLVPLKETIKGFQQILAGEYDHLPEQAFYM 97 8.1 1 5 5 3 3 0.84 0.513 0.569 4 3 4 - * * 0.640666667 0.174883771 tr|Q0QEN7|Q0QEN7_HUMAN 100 0 gi|114644226|ref|XP_509149.2| PREDICTED: ATP synthase subunit beta, mitochondrial isoform 2 [Pan troglodytes] 100 0 sp|P06576|ATPB_HUMAN ATP synthase subunit beta, mitochondrial OS=Homo sapiens GN=ATP5B PE=1 SV=3 100 0 Q0QEN7 Q0QEN7_HUMAN ATP synthase subunit beta (Fragment) OS=Homo sapiens GN=ATP5B PE=2 SV=1 BMEI0251 728 0 COG0055 F0F1-type ATP synthase, beta subunit C Energy production and conversion ; K02133|1|0.0|862|hsa:506|F-type H+-transporting ATPase subunit beta [EC:3.6.3.14] GO:0001525//angiogenesis;GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0006898//receptor-mediated endocytosis;GO:0006172//ADP biosynthetic process;GO:0051453//regulation of intracellular pH;GO:0015991//ATP hydrolysis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0042777//plasma membrane ATP synthesis coupled proton transport;GO:0006629//lipid metabolic process;GO:0006200//ATP catabolic process;GO:0022904//respiratory electron transport chain GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0030228//lipoprotein particle receptor activity;GO:0005509//calcium ion binding;GO:0042288//MHC class I protein binding;GO:0043499//eukaryotic cell surface binding;GO:0005524//ATP binding GO:0042645//mitochondrial nucleoid;GO:0009986//cell surface;GO:0005754//mitochondrial proton-transporting ATP synthase, catalytic core;GO:0005886//plasma membrane 139 sp|Q12884|SEPR_HUMAN Prolyl endopeptidase FAP OS=Homo sapiens GN=FAP PE=1 SV=5 101726 MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFSLSD 286 23.9 - 35 35 15 15 1.171 1.232 1.279 14 13 14 - * * 1.227333333 0.054151023 sp|Q12884|SEPR_HUMAN 100 0 gi|66361328|pdb|1Z68|A Chain A, Crystal Structure Of Human Fibroblast Activation Protein Alpha >gi|66361329|pdb|1Z68|B Chain B, Crystal Structure Of Human Fibroblast Activation Protein Alpha 100 0 sp|Q12884|SEPR_HUMAN Seprase OS=Homo sapiens GN=FAP PE=1 SV=5 100 0 H2QIW2 H2QIW2_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000078098 PE=4 SV=1 SPACUNK4.08 300 6.00E-81 COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases E Amino acid transport and metabolism ; K08674|1|0.0|1545|hsa:2191|fibroblast activation protein, alpha [EC:3.4.21.-] GO:0043542//endothelial cell migration;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0006508//proteolysis;GO:0051917//regulation of fibrinolysis GO:0008239//dipeptidyl-peptidase activity;GO:0004222//metalloendopeptidase activity;GO:0002020//protease binding;GO:0004252//serine-type endopeptidase activity;GO:0042803//protein homodimerization activity GO:0030054//cell junction;GO:0071438//invadopodium membrane;GO:0016021//integral to membrane;GO:0005615//extracellular space;GO:0031258//lamellipodium membrane 140 tr|A3KC71|A3KC71_HUMAN Nuclear envelope protein okuribin OS=Homo sapiens GN=okuribin PE=2 SV=1 133464 MTWRMGPRFTMLLAMWLVCGSEPHPHATIRGSHGGRKVPLVSPDSSRPARFLRHTGRSRGIERSTLEEPNLQPLQRRRSVPVLRLARPTEPPARSDINGAAVRPEQRPAARGSPREMIRDEGSSARSRMLRFPSGSSSPNILASFAGKNRVWVISAPHASEGYYRLMMSLLKDDVYCELAERHIQQIVLFHQAGEEGGKVRRITSEGQILEQPLDPSLIPKLMSFLKLEKGKFGMVLLKKTLQVEERYPYPVRLEAMYEVIDQGPIRRIEKIRQKGFVQKCKASGVEGQVVAEGNDGGGGAGRPSLGSEKKKEDPRRAQVPPTRESRVKVLRKLAATAPALPQPPSTPRATTLPPAPATTVTRSTSRAVTVAARPMTTTAFPTTQRPWTPSPSHRPPTTTEVITARRPSVSENLYPPSRKDQHRERPQTTRRPSKATSLESFTNAPPTTISEPSTRAAGXGRFRDNRMDRREHGHRDPNVVPGPPKPAKEKPPKKKAQDKILSNEYEEKYDLSRPTASQLEDELQVGNVPLKKAKESKKHEKLEKPEKEKKKKMKNENADKLLKSEKQMKKSEKKSKQEKEKSKKKKGGKTEQDGYQKPTNKHFTQSPKKSVADLLGSFEGKRRLLLITAPKAENNMYVQQRDEYLESFCKMATRKISVITIFGPVNNSTMKIDHFQLDNEKPMRVVDDEDLVDQRLISELRKEYGMTYNDFFMVLTDVDLRVKQYYEVPITMKSVFDLIDTFQSRIKDMEKQKKEGIVCKEDKKQSLENFLSRFRWRRRLLVISAPNDEDWAYSQQLSALSGQACNFGLRHITILKLLGVGEEVGGVLELFPINGSSVVEREDVPAHLVKDIRNYFQVSPEYFSMLLVGKDGNVKSWYPSPMWSMVIVYDLIDSMQLRRQEMAIQQSLGMRCPEDEYAGYGYHSYHQGYQDGYQDDYRHHESYHHGYPY 566 15.8 2 42 42 14 14 0.522 0.24 0.31 25 26 27 * * * 0.357333333 0.146837779 tr|A3KC71|A3KC71_HUMAN 100 5.00E-27 gi|27469607|gb|AAH42105.1| CCDC80 protein [Homo sapiens] 99.89 0 sp|Q76M96|CCD80_HUMAN Coiled-coil domain-containing protein 80 OS=Homo sapiens GN=CCDC80 PE=1 SV=1 100 2.00E-26 F7GYI8 F7GYI8_CALJA Uncharacterized protein OS=Callithrix jacchus GN=CCDC80 PE=4 SV=1 - - - - - - - - - - GO:0005578//proteinaceous extracellular matrix 141 sp|P07195|LDHB_HUMAN L-lactate dehydrogenase B chain OS=Homo sapiens GN=LDHB PE=1 SV=2 >tr|Q5U077|Q5U077_HUMAN L-lactate dehydrogenase OS=Homo sapiens GN=LDHB PE=2 SV=1 45114 MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL 1014 21.6 - 45 42 6 5 0.885 0.739 0.765 27 28 28 - - * 0.796333333 0.07788025 sp|P07195|LDHB_HUMAN 100 0 gi|4557032|ref|NP_002291.1| L-lactate dehydrogenase B chain [Homo sapiens] >gi|291575128|ref|NP_001167568.1| L-lactate dehydrogenase B chain [Homo sapiens] >gi|307775433|ref|NP_001182738.1| lactate dehydrogenase B [Macaca mulatta] >gi|126041|sp|P07195.2|LDHB_HUMAN RecName: Full=L-lactate dehydrogenase B chain; Short=LDH-B; AltName: Full=LDH heart subunit; Short=LDH-H; AltName: Full=Renal carcinoma antigen NY-REN-46 >gi|75075979|sp|Q4R5B6.3|LDHB_MACFA RecName: Full=L-lactate dehydrogenase B chain; Short=LDH-B >gi|1200083|emb|CAA32033.1| lactate dehydrogenase B [Homo sapiens] >gi|12803117|gb|AAH02362.1| Lactate dehydrogenase B [Homo sapiens] >gi|15929376|gb|AAH15122.1| Lactate dehydrogenase B [Homo sapiens] >gi|37779174|gb|AAO85222.1| transformation-related protein 5 [Homo sapiens] >gi|48734977|gb|AAH71860.1| Lactate dehydrogenase B [Homo sapiens] >gi|54696394|gb|AAV38569.1| lactate dehydrogenase B [Homo sapiens] >gi|54696396|gb|AAV38570.1| lactate dehydrogenase B [Homo sapiens] >gi|119616854|gb|EAW96448.1| lactate dehydrogenase B, isoform CRA_a [Homo sapiens] >gi|119616855|gb|EAW96449.1| lactate dehydrogenase B, isoform CRA_a [Homo sapiens] >gi|195542262|gb|ACF98331.1| lactate dehydrogenase B [Homo sapiens] >gi|402239600|gb|AFQ39751.1| lactate dehydrogenase B [Gorilla gorilla] >gi|402239602|gb|AFQ39752.1| lactate dehydrogenase B [Pongo pygmaeus] >gi|402239604|gb|AFQ39753.1| lactate dehydrogenase B [Hylobates lar] >gi|402239606|gb|AFQ39754.1| lactate dehydrogenase B [Papio anubis] >gi|402239608|gb|AFQ39755.1| lactate dehydrogenase B [Theropithecus gelada] 100 0 sp|Q4R5B6|LDHB_MACFA L-lactate dehydrogenase B chain OS=Macaca fascicularis GN=LDHB PE=2 SV=3 100 0 H2NGT2 H2NGT2_PONAB L-lactate dehydrogenase OS=Pongo abelii GN=LOC100453434 PE=3 SV=1 CAC0267 270 3.00E-72 COG0039 Malate/lactate dehydrogenases C Energy production and conversion ; K00016|1|0.0|682|mcc:696935|L-lactate dehydrogenase [EC:1.1.1.27] GO:0055114//oxidation-reduction process;GO:0006090//pyruvate metabolic process;GO:0006089//lactate metabolic process;GO:0044262//cellular carbohydrate metabolic process;GO:0019674//NAD metabolic process;GO:0006096//glycolysis GO:0051287//NAD binding;GO:0042802//identical protein binding;GO:0004459//L-lactate dehydrogenase activity GO:0005829//cytosol;GO:0005739//mitochondrion 142 tr|A0A075B6H2|A0A075B6H2_HUMAN Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Homo sapiens GN=SVEP1 PE=4 SV=1 451196 MSPSRNFSFRLFPETAPGAPGSIPAPPAPGDEAAGSRVERLGQAFRRRVRLLRELSERLELVFLVDDSSSVGEVNFRSELMFVRKLLSDFPVVPTATRVAIVTFSSKNYVVPRVDYISTRRARQHKCALLLQEIPAISYRGGGTYTKGAFQQAAQILLHARENSTKVVFLITDGYSNGGDPRPIAASLRDSGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQDDMVHCSYLCDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEAKTLEQQDSANVTWQIPTAKDNSGEKVSVHVHPAFTPPYLFPIGDVAIVYTATDLSGNQASCIFHIKVIDAEPPVIDWCRSPPPVQVSEKVHAASWDEPQFSDNSGAELVITRSHTQGDLFPQGETIVQYTATDPSGNNRTCDIHIVIKGSPCEIPFTPVNGDFICTPDNTGVNCTLTCLEGYDFTEGSTDKYYCAYEDGVWKPTYTTEWPDCAKKRFANHGFKSFEMFYKAARCDDTDLMKKFSEAFETTLGKMVPSFCSDAEDIDCRLEENLTKKYCLEYNYDYENGFAIGPGGWGAANRLDYSYDDFLDTVQETATSIGNAKSSRIKRSAPLSDYKIKLIFNITASVPLPDERNDTLEWENQQRLLQTLETITNKLKRTLNKDPMYSFQLASEILIADSNSLETKKASPFCRPGSVLRGRMCVNCPLGTYYNLEHFTCESCRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQCKQGTYSYSGLETCESCPLGTYQPKFGSRSCLSCPENTSTVKRGAVNISACGVPCPEGKFSRSGLMPCHPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQSTGFNLDFEVSGIYGYVMLDGMLPSLHALTCTFWMKSSDDMNYGTPISYAVDNGSDNTLLLTDYNGWVLYVNGREKITNCPSVNDGRWHHIAITWTSANGIWKVYIDGKLSDGGAGLSVGLPIPGGGALVLGQEQDKKGEGFSPAESFVGSISQLNLWDYVLSPQQVKSLATSCPEELSKGNVLAWPDFLSGIVGKVKIDSKSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCSRKRRTGF 1148 8.2 1 56 56 23 23 2.154 3.117 3.208 39 34 34 * - * 2.826333333 0.584032819 tr|A0A075B6H2|A0A075B6H2_HUMAN 100 0 gi|148886654|ref|NP_699197.3| sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 precursor [Homo sapiens] >gi|296452942|sp|Q4LDE5.3|SVEP1_HUMAN RecName: Full=Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1; AltName: Full=CCP module-containing protein 22; AltName: Full=Polydom; AltName: Full=Selectin-like osteoblast-derived protein; Short=SEL-OB; AltName: Full=Serologically defined breast cancer antigen NY-BR-38; Flags: Precursor 100 0 sp|Q4LDE5|SVEP1_HUMAN Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Homo sapiens GN=SVEP1 PE=1 SV=3 99.93 0 E9PBN8 E9PBN8_HUMAN Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Homo sapiens GN=SVEP1 PE=4 SV=1 - - - - - - - K04011|1|5e-162|574|ecb:100057298|complement component (3b/4b) receptor 1 GO:0007155//cell adhesion GO:0005509//calcium ion binding;GO:0003682//chromatin binding GO:0005576//extracellular region;GO:0016020//membrane;GO:0005737//cytoplasm 143 sp|Q15293|RCN1_HUMAN Reticulocalbin-1 OS=Homo sapiens GN=RCN1 PE=1 SV=1 >tr|V9HW95|V9HW95_HUMAN Epididymis secretory protein Li 84 OS=Homo sapiens GN=HEL-S-84 PE=2 SV=1 47384 MARGGRGRRLGLALGLLLALVLAPRVLRAKPTVRKERVVRPDSELGERPPEDNQSFQYDHEAFLGKEDSKTFDQLTPDESKERLGKIVDRIDNDGDGFVTTEELKTWIKRVQKRYIFDNVAKVWKDYDRDKDDKISWEEYKQATYGYYLGNPAEFHDSSDHHTFKKMLPRDERRFKAADLNGDLTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEENGPEPDWVLSEREQFNEFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEKLTKEEILENWNMFVGSQATNYGEDLTKNHDEL 540 25.1 - 33 33 9 9 1.352 1.191 1.252 17 19 18 * * * 1.265 0.081283455 sp|Q15293|RCN1_HUMAN 100 4.00E-91 gi|41350407|gb|AAS00491.1| proliferation-inducing gene 20 protein [Homo sapiens] 100 2.00E-176 sp|Q15293|RCN1_HUMAN Reticulocalbin-1 OS=Homo sapiens GN=RCN1 PE=1 SV=1 100 9.00E-61 E9PJD5 E9PJD5_HUMAN Reticulocalbin-1 OS=Homo sapiens GN=RCN1 PE=4 SV=1 - - - - - - - - GO:0001701//in utero embryonic development;GO:0043010//camera-type eye development GO:0005515//protein binding;GO:0005509//calcium ion binding GO:0005788//endoplasmic reticulum lumen 144 tr|B1ANR0|B1ANR0_HUMAN Poly(A) binding protein, cytoplasmic 4 (Inducible form), isoform CRA_e OS=Homo sapiens GN=PABPC4 PE=1 SV=1 82758 MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPTLRHLAPTGVPTAVQNLAPRAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS 85 9.6 2 5 4 5 4 0.838 0.785 0.835 2 2 2 - - - 0.819333333 0.029771351 tr|B1ANR0|B1ANR0_HUMAN 100 0 gi|119627670|gb|EAX07265.1| poly(A) binding protein, cytoplasmic 4 (inducible form), isoform CRA_e [Homo sapiens] 95.35 0 sp|Q13310|PABP4_HUMAN Polyadenylate-binding protein 4 OS=Homo sapiens GN=PABPC4 PE=1 SV=1 100 0 B1ANR0 B1ANR0_HUMAN Poly(A) binding protein, cytoplasmic 4 (Inducible form) OS=Homo sapiens GN=PABPC4 PE=4 SV=1 YCL011c 87.8 5.00E-17 COG0724 RNA-binding proteins (RRM domain) R General function prediction only ; K13126|1|0.0|1141|ecb:100054235|polyadenylate-binding protein GO:0006412//translation;GO:0006396//RNA processing;GO:0006401//RNA catabolic process;GO:0007596//blood coagulation GO:0008266//poly(U) RNA binding;GO:0017130//poly(C) RNA binding;GO:0008143//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus 145 tr|B2R4V4|B2R4V4_HUMAN cDNA, FLJ92232, highly similar to Homo sapiens barrier to autointegration factor 1 (BANF1), mRNA OS=Homo sapiens PE=2 SV=1 13280 MTTSQKHRDFGAEPMGEKPVGSLAGIGEVLGKKLEERGFDKAYVVLGQFLVLKKDEDLFREWLKDTCGANAKQSRDCFGCLREWCDAFL 102 13.5 1 2 2 1 1 2.29 0.896 1.114 2 2 2 - - * 1.433333333 0.749859542 tr|B2R4V4|B2R4V4_HUMAN 100 3.00E-45 gi|189065178|dbj|BAG34901.1| unnamed protein product [Homo sapiens] 98.88 2.00E-45 sp|Q5RBU9|BAF_PONAB Barrier-to-autointegration factor OS=Pongo abelii GN=BANF1 PE=3 SV=1 100 1.00E-44 B2R4V4 B2R4V4_HUMAN cDNA, FLJ92232, highly similar to Homo sapiens barrier to autointegration factor 1 (BANF1), mRNA OS=Homo sapiens PE=4 SV=1 - - - - - - - - GO:0050792//regulation of viral reproduction;GO:0075713//establishment of integrated proviral latency;GO:0009615//response to virus;GO:0015074//DNA integration GO:0003677//DNA binding;GO:0005515//protein binding GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0005829//cytosol 146 tr|B2R6P1|B2R6P1_HUMAN cDNA, FLJ93045, highly similar to Homo sapiens galactosamine (N-acetyl)-6-sulfate sulfatase (Morquiosyndrome, mucopolysaccharidosis type IVA) (GALNS), mRNA OS=Homo sapiens PE=2 SV=1 63849 MAAVVAATRWWQLLLVLSAAGMGASGAPQPPNILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAGGLLFPNFYSANPLCSPSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLGHRPQFHPLKHGFDEWFGSPNCHFGPYDNKARPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKPFLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDTLMAATLGQHKAHFWTWTNSWENFRQGIDFCPGQNVSGVTTHNLEDHTKLPLIFHLGRDPGERFPLSFASAEYQEALSRITSVVQQHQEALVPAQPQLNVCNWAVMNWAPPGCEKLGKCLTPPESIPKKCLWSH 139 5.4 3 10 10 3 3 1.476 1.898 1.613 8 7 7 * * * 1.662333333 0.215281986 tr|B2R6P1|B2R6P1_HUMAN 100 0 gi|189069200|dbj|BAG35538.1| unnamed protein product [Homo sapiens] 99.81 0 sp|P34059|GALNS_HUMAN N-acetylgalactosamine-6-sulfatase OS=Homo sapiens GN=GALNS PE=1 SV=1 100 0 Q6YL38 Q6YL38_HUMAN Putative uncharacterized protein OS=Homo sapiens PE=2 SV=1 SMa1683 181 2.00E-45 COG3119 Arylsulfatase A and related enzymes P Inorganic ion transport and metabolism ; K01132|1|0.0|1046|hsa:2588|N-acetylgalactosamine-6-sulfatase [EC:3.1.6.4] GO:0042340//keratan sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process GO:0046872//metal ion binding;GO:0043890//N-acetylgalactosamine-6-sulfatase activity;GO:0003943//N-acetylgalactosamine-4-sulfatase activity GO:0043202//lysosomal lumen 147 tr|C9J0K6|C9J0K6_HUMAN Sorcin OS=Homo sapiens GN=SRI PE=1 SV=1 20008 MQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV 59 14.2 1 4 4 2 2 0.943 0.864 0.996 2 2 2 - - - 0.934333333 0.066425397 tr|C9J0K6|C9J0K6_HUMAN 100 1.00E-49 gi|119597317|gb|EAW76911.1| sorcin, isoform CRA_b [Homo sapiens] 100 2.00E-88 sp|P30626|SORCN_HUMAN Sorcin OS=Homo sapiens GN=SRI PE=1 SV=1 100 7.00E-87 F7INJ3 F7INJ3_CALJA Uncharacterized protein OS=Callithrix jacchus GN=LOC100394623 PE=4 SV=1 - - - - - - - K07359|1|7e-30|129|dpo:Dpse_GA27481|calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17]!K08585|2|4e-27|120|tad:TRIADDRAFT_63582|calpain, invertebrate [EC:3.4.22.-] GO:0001508//regulation of action potential;GO:0008016//regulation of heart contraction;GO:0007517//muscle organ development;GO:0006942//regulation of striated muscle contraction;GO:0007507//heart development;GO:0006880//intracellular sequestering of iron ion;GO:0006816//calcium ion transport;GO:0007165//signal transduction GO:0005246//calcium channel regulator activity;GO:0005509//calcium ion binding;GO:0005102//receptor binding;GO:0046982//protein heterodimerization activity GO:0030018//Z disc;GO:0031982//vesicle;GO:0033017//sarcoplasmic reticulum membrane;GO:0005886//plasma membrane 148 tr|Q6X907|Q6X907_HUMAN Neuropilin-1 OS=Homo sapiens GN=NRP1 PE=2 SV=1 118908 MERGLPLLCAVLALVLAPAGAFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDYVEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITDYPCSGMLGMVSGLISDSQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSYINEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTFPALSTRFIRIYPERATHGGLGLRMELLGCEVEAPTAGPTTPNGNLVDECDDDQANCHSGTGDDFQLTGGTTVLATEKPTVIDSTIQSEFPTYGFNCEFGWGSHKTFCHWEHDNHVQLKWSVLTSKTGPIQDHTGDGNFIYSQADENQKGKVARLVSPVVYSQNSAHCMTFWYHMSGSHVGTLRVKLRYQKPEEYHQLVWMAIGHQGDHWKEGRVLLHKSLKLYQVIFEGEIGKGNLGGIAVDDISINNHISQEDCARSTPGYEGEGEGDKNISRKPGNVLKTLDPILITIIAMSALGVLLGAVCGVVLYCACWHNGMSERNLSALENYNFELVDGVKLKKDKLNTQSTYSEA 251 6.6 5 9 9 5 5 0.931 1.108 1.289 7 7 6 - - - 1.109333333 0.179003724 tr|Q6X907|Q6X907_HUMAN 100 0 gi|32331165|gb|AAP80144.1| neuropilin-1 [Homo sapiens] 97.78 0 sp|O14786|NRP1_HUMAN Neuropilin-1 OS=Homo sapiens GN=NRP1 PE=1 SV=3 100 0 Q6AWA9 Q6AWA9_HUMAN Putative uncharacterized protein DKFZp686A03134 (Fragment) OS=Homo sapiens GN=DKFZp686A03134 PE=2 SV=1 - - - - - - - K06724|1|0.0|1734|mcc:697755|neuropilin 1 GO:0030501//positive regulation of bone mineralization;GO:0010468//regulation of gene expression;GO:0071526//semaphorin-plexin signaling pathway;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0060301//positive regulation of cytokine activity;GO:0010595//positive regulation of endothelial cell migration;GO:0045669//positive regulation of osteoblast differentiation;GO:0007507//heart development;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0016358//dendrite development;GO:0014911//positive regulation of smooth muscle cell migration;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048485//sympathetic nervous system development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0035767//endothelial cell chemotaxis;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0001569//patterning of blood vessels;GO:0007267//cell-cell signaling;GO:0060666//dichotomous subdivision of terminal units involved in salivary gland branching;GO:0007155//cell adhesion;GO:0033689//negative regulation of osteoblast proliferation;GO:0007413//axonal fasciculation;GO:0021636//trigeminal nerve morphogenesis;GO:2000599//negative regulation of cyclin catabolic process;GO:0009611//response to wounding;GO:0009887//organ morphogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0060627//regulation of vesicle-mediated transport;GO:0006917//induction of apoptosis GO:0005080//protein kinase C binding;GO:0017154//semaphorin receptor activity;GO:0008201//heparin binding;GO:0015026//coreceptor activity;GO:0019955//cytokine binding;GO:0019838//growth factor binding;GO:0005509//calcium ion binding;GO:0005021//vascular endothelial growth factor-activated receptor activity GO:0031410//cytoplasmic vesicle;GO:0009986//cell surface;GO:0030426//growth cone;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral to membrane;GO:0005635//nuclear envelope;GO:0005883//neurofilament;GO:0002116//semaphorin receptor complex;GO:0043025//neuronal cell body;GO:0005576//extracellular region 149 sp|P31150|GDIA_HUMAN Rab GDP dissociation inhibitor alpha OS=Homo sapiens GN=GDI1 PE=1 SV=2 60304 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETVNRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQVIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGCESQVFCSCSYDATTHFETTCNDIKDIYKRMAGTAFDFENMKRKQNDVFGEAEQ 238 16.1 - 21 8 7 3 0.725 0.563 0.816 2 2 2 - - - 0.701333333 0.128149652 sp|P31150|GDIA_HUMAN 100 0 gi|4503971|ref|NP_001484.1| rab GDP dissociation inhibitor alpha [Homo sapiens] >gi|57113993|ref|NP_001009061.1| rab GDP dissociation inhibitor alpha [Pan troglodytes] >gi|1707886|sp|P31150.2|GDIA_HUMAN RecName: Full=Rab GDP dissociation inhibitor alpha; Short=Rab GDI alpha; AltName: Full=Guanosine diphosphate dissociation inhibitor 1; Short=GDI-1; AltName: Full=Oligophrenin-2; AltName: Full=Protein XAP-4 >gi|38502873|sp|P60028.1|GDIA_PANTR RecName: Full=Rab GDP dissociation inhibitor alpha; Short=Rab GDI alpha; AltName: Full=Guanosine diphosphate dissociation inhibitor 1; Short=GDI-1 >gi|15217061|gb|AAK92482.1|AF400433_1 GDP dissociation inhibitor 1 [Homo sapiens] >gi|695523|emb|CAA55909.1| GDP-dissociation inhibitor [Homo sapiens] >gi|695585|emb|CAA55908.1| GDP-dissociation inhibitor [Homo sapiens] >gi|1203973|gb|AAA92648.1| GDI [Homo sapiens] >gi|12653101|gb|AAH00317.1| GDP dissociation inhibitor 1 [Homo sapiens] >gi|15126544|gb|AAH12201.1| GDP dissociation inhibitor 1 [Homo sapiens] >gi|33354065|dbj|BAC81116.1| GDP dissociation inhibitor 1 [Homo sapiens] >gi|33354067|dbj|BAC81117.1| GDP dissociation inhibitor 1 [Pan troglodytes] >gi|49457510|emb|CAG47054.1| GDI1 [Homo sapiens] >gi|49457546|emb|CAG47072.1| GDI1 [Homo sapiens] >gi|54696630|gb|AAV38687.1| GDP dissociation inhibitor 1 [Homo sapiens] >gi|56122336|gb|AAV74319.1| GDP dissociation inhibitor 1 [Pan troglodytes] >gi|119593116|gb|EAW72710.1| GDP dissociation inhibitor 1, isoform CRA_b [Homo sapiens] >gi|146741460|dbj|BAF62386.1| GDP dissociation inhibitor 1 [Pan troglodytes verus] 100 0 sp|P60028|GDIA_PANTR Rab GDP dissociation inhibitor alpha OS=Pan troglodytes GN=GDI1 PE=2 SV=1 100 0 G3RCC0 G3RCC0_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=GDI1 PE=4 SV=1 SPAC22H10.12c 522 6.00E-148 COG5044 RAB proteins geranylgeranyltransferase component A (RAB escort protein) O Posttranslational modification, protein turnover, chaperones ; - GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0051592//response to calcium ion GO:0005515//protein binding;GO:0005096//GTPase activator activity;GO:0005093//Rab GDP-dissociation inhibitor activity GO:0005829//cytosol;GO:0043234//protein complex;GO:0043005//neuron projection;GO:0030496//midbody 150 tr|A0A087WTA8|A0A087WTA8_HUMAN Collagen alpha-2(I) chain OS=Homo sapiens GN=COL1A2 PE=4 SV=1 145100 MLSFVDTRTLLLLAVTLCLATCQFFETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLRPKDYEVDATLKSLNNQIETLLTPEGSRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMDAIKVYCDFSTGETCIRAQPENIPAKNWYRSSKDKKHVWLGETINAGSQFEYNVEGVTSKEMATQLAFMRLLANYASQNITYHCKNSIAYMDEETGNLKKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWGKTIIEYKTNKPSRLPFLDIAPLDIGGADQEFFVDIGPVCFK 17532 49.9 1 533 533 38 38 1.455 1.762 1.705 408 417 408 - - - 1.640666667 0.163298296 tr|A0A087WTA8|A0A087WTA8_HUMAN 100 7.00E-12 gi|32451581|gb|AAH54498.1| Collagen, type I, alpha 2 [Homo sapiens] >gi|45708783|gb|AAH42586.1| Collagen, type I, alpha 2 [Homo sapiens] >gi|119597202|gb|EAW76796.1| collagen, type I, alpha 2, isoform CRA_c [Homo sapiens] 100 0 sp|P08123|CO1A2_HUMAN Collagen alpha-2(I) chain OS=Homo sapiens GN=COL1A2 PE=1 SV=7 100 1.00E-10 G1RZZ2 G1RZZ2_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=COL1A2 PE=4 SV=1 - - - - - - - K06236|1|0.0|646|hsa:1278|collagen, type I/II/III/V/XI, alpha GO:0001501//skeletal system development;GO:0007411//axon guidance;GO:0043589//skin morphogenesis;GO:0007266//Rho protein signal transduction;GO:0030168//platelet activation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001568//blood vessel development;GO:0042476//odontogenesis;GO:0050900//leukocyte migration;GO:0030199//collagen fibril organization;GO:0008217//regulation of blood pressure GO:0005201//extracellular matrix structural constituent;GO:0048407//platelet-derived growth factor binding;GO:0030674//protein binding, bridging;GO:0042802//identical protein binding GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005584//collagen type I 151 tr|B1AKR6|B1AKR6_HUMAN Dynein light chain roadblock-type 1 OS=Homo sapiens GN=DYNLRB1 PE=1 SV=1 18961 MGEGWAAALQPRVLGPWCAMATLATFPGSSVCGRLCQALYVSCISSASSQLCEAEVEETLKRLQSQKGVQGIIVVNTEGIPIKSTMDNPTTTQYASLMHSFILKARSTVRDIDPQNDLTFLRIRSKKNEIMVAPDKDYFLIVIQNPTE 130 10.8 2 2 2 1 1 0.528 0.694 0.593 2 2 2 - * - 0.605 0.083648072 tr|B1AKR6|B1AKR6_HUMAN 100 3.00E-50 gi|82408040|pdb|2B95|A Chain A, Solution Nmr Structure Of Protein Dynein Light Chain 2a, Cytoplasmic; Northeast Structural Genomics Consortium Target Hr2106 >gi|82408041|pdb|2B95|B Chain B, Solution Nmr Structure Of Protein Dynein Light Chain 2a, Cytoplasmic; Northeast Structural Genomics Consortium Target Hr2106 100 1.00E-50 sp|Q9NP97|DLRB1_HUMAN Dynein light chain roadblock-type 1 OS=Homo sapiens GN=DYNLRB1 PE=1 SV=3 100 1.00E-82 B1AKR6 B1AKR6_HUMAN Dynein light chain roadblock-type 1 OS=Homo sapiens GN=DYNLRB1 PE=4 SV=1 - - - - - - - K10419|1|1e-50|198|pon:100443115|dynein light chain roadblock-type GO:0007632//visual behavior;GO:0008090//retrograde axon cargo transport GO:0042802//identical protein binding;GO:0003777//microtubule motor activity GO:0005813//centrosome;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule 152 sp|Q8WX93|PALLD_HUMAN Palladin OS=Homo sapiens GN=PALLD PE=1 SV=3 173133 MSGTSSHESFYDSLSDMQEESKNTDFFPGLSAFLSQEEINKSLDLARRAIADSETEDFDSEKEISQIFSTSPASLCEHPSHKETKLGEHASRRPQDNRSTPVQPLAEKQTKSISSPVSKRKPAMSPLLTRPSYIRSLRKAEKRGAKTPSTNVKPKTPHQRKGGPQSQLCDKAANLIEELTSIFKAAKPRNRSPNGESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLDPLKLQQLQNQIRLEQEAGARQPPPAPRSAPPSPPFPPPPAFPELAACTPPASPEPMSALASRSAPAMQSSGSFNYARPKQFIAAQNLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPPPPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHSQTPAAFLSALLPSQPPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL 138 2.5 - 5 5 3 3 0.6 0.562 0.717 4 4 2 - * - 0.626333333 0.080785725 sp|Q8WX93|PALLD_HUMAN 100 0 gi|260656032|ref|NP_001159581.1| palladin isoform 3 [Homo sapiens] 100 0 sp|Q8WX93|PALLD_HUMAN Palladin OS=Homo sapiens GN=PALLD PE=1 SV=3 100 3.00E-94 F8WA26 F8WA26_HUMAN Palladin (Fragment) OS=Homo sapiens GN=PALLD PE=4 SV=1 - - - - - - - K12567|1|4e-54|214|bta:540561|titin [EC:2.7.11.1] GO:0007010//cytoskeleton organization GO:0051371//muscle alpha-actinin binding;GO:0003779//actin binding GO:0030018//Z disc;GO:0030027//lamellipodium;GO:0005884//actin filament;GO:0005925//focal adhesion;GO:0001726//ruffle;GO:0005634//nucleus 153 tr|A0A075B6E2|A0A075B6E2_HUMAN 40S ribosomal protein S19 OS=Homo sapiens GN=RPS19 PE=1 SV=1 10260 MTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH 84 12.7 2 4 4 1 1 1.737 1.039 1.165 2 2 2 - - - 1.313666667 0.371991039 tr|A0A075B6E2|A0A075B6E2_HUMAN 100 1.00E-33 gi|50981396|gb|AAT91476.1| ribosomal protein S19 [Felis catus] 100 5.00E-35 sp|P39019|RS19_HUMAN 40S ribosomal protein S19 OS=Homo sapiens GN=RPS19 PE=1 SV=2 100 2.00E-33 H2QGF0 H2QGF0_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000105372 PE=4 SV=1 SPBC649.02 68.2 3.00E-12 COG2238 Ribosomal protein S19E (S16A) J Translation, ribosomal structure and biogenesis ; K02966|1|2e-35|147|cfa:476450|small subunit ribosomal protein S19e GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006415//translational termination;GO:0006413//translational initiation;GO:0051272//positive regulation of cellular component movement;GO:0006414//translational elongation;GO:0030218//erythrocyte differentiation;GO:0009991//response to extracellular stimulus;GO:0019083//viral transcription;GO:0042274//ribosomal small subunit biogenesis;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0015669//gas transport;GO:0006364//rRNA processing GO:0005515//protein binding;GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding GO:0005730//nucleolus;GO:0022627//cytosolic small ribosomal subunit 154 sp|Q02952|AKA12_HUMAN A-kinase anchor protein 12 OS=Homo sapiens GN=AKAP12 PE=1 SV=4 237263 MGAGSSTEQRSPEQPPEGSSTPAEPEPSGGGPSAEAAPDTTADPAIAASDPATKLLQKNGQLSTINGVAEQDELSLQEGDLNGQKGALNGQGALNSQEEEEVIVTEVGQRDSEDVSKRDSDKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNLEELTQPTESQANDIGFKKVFKFVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHKDPSLGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQEEQKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTSVSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILETGETLEPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVDEQVACQEVKVSVAIEDLEPENGILELETKSSKLVQNIIQTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKSLVEPKEDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSESDKAITPQAQEELQKQERESAKSELTES 168 4.6 - 8 8 5 5 0.744 1.012 0.597 5 5 5 - - * 0.784333333 0.210419422 sp|Q02952|AKA12_HUMAN 100 0 gi|21493022|ref|NP_005091.2| A-kinase anchor protein 12 isoform 1 [Homo sapiens] >gi|317373554|sp|Q02952.4|AKA12_HUMAN RecName: Full=A-kinase anchor protein 12; Short=AKAP-12; AltName: Full=A-kinase anchor protein 250 kDa; Short=AKAP 250; AltName: Full=Gravin; AltName: Full=Myasthenia gravis autoantigen 100 0 sp|Q02952|AKA12_HUMAN A-kinase anchor protein 12 OS=Homo sapiens GN=AKAP12 PE=1 SV=4 99.39 7.00E-95 Q86TJ9 Q86TJ9_HUMAN AKAP12 protein (Fragment) OS=Homo sapiens GN=AKAP12 PE=2 SV=1 - - - - - - - - GO:0030819//positive regulation of cAMP biosynthetic process;GO:0006605//protein targeting;GO:0010739//positive regulation of protein kinase A signaling cascade;GO:0007186//G-protein coupled receptor signaling pathway GO:0051018//protein kinase A binding;GO:0008179//adenylate cyclase binding GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0005886//plasma membrane 155 tr|A0A087WTE1|A0A087WTE1_HUMAN Inter-alpha-trypsin inhibitor heavy chain H2 OS=Homo sapiens GN=ITIH2 PE=1 SV=1 126819 MKRLTCFFICFFLSEVSGFEIPINGLSEFVDYEDLVELAPGKFQLVAENRRYQRSLPGESEEMMEEVDQVTLYSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFSMTVDGKTFRSSIKEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFELHYQEVKWRKLGSYEHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHVPDTFEGHFDGVPVISKGQQKAHVSFKPTVAQQRICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVHFFAPDNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRNDLFQLQKHRLQMPRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQDTSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQIESVITATSANTQLVLETLAQMDDLQDFLSKDKHADPDFTRKLWAYLTINQLLAERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQDPSCCSGALYYGSKVVPDSTPSWANPSPTPVISMLAQGSQVLESTPPPHVMRVENDPHFIIYLPKSQKNICFNIDSEPGKILNLVSDPESGIVVNGQLVGAKKPNNGKLSTYFGKLGFYFQSEDIKIEISTETITLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFSVLLHRVWKKHPVNVDFLGIYIPPTNKFSPKAHGLIGQFMQEPKIHIFNERPGKDPEKPEASMEVKGQKLIITRGLQKDYRTDLVFGTDVTCWFVHNSGKGFIDGHYKDYFVPQLYSFLKRP 510 10.2 4 26 26 8 8 0.627 1.243 1.044 18 17 15 * - - 0.971333333 0.314363378 tr|A0A087WTE1|A0A087WTE1_HUMAN 99.58 0 gi|33985|emb|CAA30160.1| trypsin inhibitor [Homo sapiens] 98.84 0 sp|P19823|ITIH2_HUMAN Inter-alpha-trypsin inhibitor heavy chain H2 OS=Homo sapiens GN=ITIH2 PE=1 SV=2 98.73 0 A2RTY6 A2RTY6_HUMAN Inter-alpha (Globulin) inhibitor H2 OS=Homo sapiens GN=ITIH2 PE=2 SV=1 alr4412 116 2.00E-25 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R General function prediction only ; K04861|1|3e-07|58.2|xtr:100488361|voltage-dependent calcium channel alpha-2/delta-4 GO:0030212//hyaluronan metabolic process;GO:0010951//negative regulation of endopeptidase activity GO:0004867//serine-type endopeptidase inhibitor activity GO:0005576//extracellular region 156 sp|P05997|CO5A2_HUMAN Collagen alpha-2(V) chain OS=Homo sapiens GN=COL5A2 PE=1 SV=3 164651 MMANWAEARPLLILIVLLGQFVSIKAQEEDEDEGYGEEIACTQNGQMYLNRDIWKPAPCQICVCDNGAILCDKIECQDVLDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKVYCNMETGETCISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQSPNTAITQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRYIVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV 1971 23.6 - 69 69 20 20 1.396 1.821 1.781 55 53 53 * * * 1.666 0.234680634 sp|P05997|CO5A2_HUMAN 100 0 gi|62087670|dbj|BAD92282.1| alpha 2 type V collagen preproprotein variant [Homo sapiens] 100 8.00E-148 sp|P05997|CO5A2_HUMAN Collagen alpha-2(V) chain OS=Homo sapiens GN=COL5A2 PE=1 SV=3 100 3.00E-43 F6V6S9 F6V6S9_MACMU Uncharacterized protein (Fragment) OS=Macaca mulatta GN=COL5A2 PE=4 SV=1 - - - - - - - K06236|1|0.0|816|pon:100457541|collagen, type I/II/III/V/XI, alpha GO:0048592//eye morphogenesis;GO:0042221//response to chemical stimulus;GO:0043588//skin development;GO:0030199//collagen fibril organization - GO:0005588//collagen type V 157 sp|Q9Y281|COF2_HUMAN Cofilin-2 OS=Homo sapiens GN=CFL2 PE=1 SV=1 >tr|Q549N0|Q549N0_HUMAN Cofilin 2 (Muscle), isoform CRA_a OS=Homo sapiens GN=CFL2 PE=2 SV=1 26140 MASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL 563 31.9 - 29 10 5 2 0.639 0.75 0.671 8 8 8 * * * 0.686666667 0.057134345 sp|Q9Y281|COF2_HUMAN 100 3.00E-91 gi|338717974|ref|XP_001490861.2| PREDICTED: cofilin-2-like [Equus caballus] 100 2.00E-92 sp|Q9Y281|COF2_HUMAN Cofilin-2 OS=Homo sapiens GN=CFL2 PE=1 SV=1 100 1.00E-23 Q5MAR8 Q5MAR8_CANFA Cofilin 2 (Fragment) OS=Canis familiaris PE=4 SV=1 - - - - - - - K05765|1|2e-93|340|ptr:452853|cofilin - GO:0003779//actin binding GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0016363//nuclear matrix 158 tr|A0A0A0MR52|A0A0A0MR52_HUMAN Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens GN=EIF4G1 PE=4 SV=1 179893 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPQAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTENASKGSLTSFLRRPFQSPTSLWPMQHVPLPHGAESAHYGKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPRPLTRSIRRLRWKTSRAHQSAAAHPRAVTSVGAVLQALPSAVDFPLWMMVANTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERVNGEGTVGTGLIVRTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEEGATGALRLQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAGGV 85 0.8 13 4 4 1 1 0.443 0.788 0.764 3 3 3 - - - 0.665 0.192631773 tr|A0A0A0MR52|A0A0A0MR52_HUMAN 100 7.00E-12 gi|351709618|gb|EHB12537.1| Eukaryotic translation initiation factor 4 gamma 1 [Heterocephalus glaber] 92.51 0 sp|Q04637|IF4G1_HUMAN Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens GN=EIF4G1 PE=1 SV=4 100 8.00E-87 C9JWW9 C9JWW9_HUMAN Eukaryotic translation initiation factor 4 gamma 1 (Fragment) OS=Homo sapiens GN=EIF4G1 PE=4 SV=1 - - - - - - - K03260|1|0.0|1958|hsa:1981|translation initiation factor 4G GO:0008286//insulin receptor signaling pathway;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0019221//cytokine-mediated signaling pathway;GO:0006446//regulation of translational initiation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003743//translation initiation factor activity;GO:0005515//protein binding GO:0016281//eukaryotic translation initiation factor 4F complex;GO:0005829//cytosol 159 tr|C9JFR7|C9JFR7_HUMAN Cytochrome c (Fragment) OS=Homo sapiens GN=CYCS PE=1 SV=1 17220 MGDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKK 133 25.7 1 18 18 3 3 0.983 0.885 0.72 7 7 6 - - * 0.862666667 0.13291476 tr|C9JFR7|C9JFR7_HUMAN 100 5.00E-52 gi|159162530|pdb|1J3S|A Chain A, Solution Structure Of Reduced Recombinant Human Cytochrome C >gi|229162|prf||630485A cytochrome c 100 1.00E-53 sp|Q6WUX8|CYC_GORGO Cytochrome c OS=Gorilla gorilla gorilla GN=CYCS PE=3 SV=3 100 5.00E-52 G4XXM6 G4XXM6_HYLLA Cytochrome c OS=Hylobates lar GN=CYCS PE=3 SV=1 SPCC191.07 147 4.00E-36 COG3474 Cytochrome c2 C Energy production and conversion ; K08738|1|1e-53|207|pon:100171479|cytochrome c GO:0006309//apoptotic DNA fragmentation;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0022904//respiratory electron transport chain;GO:0044281//small molecule metabolic process GO:0045155//electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0020037//heme binding;GO:0005506//iron ion binding GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0070469//respiratory chain;GO:0000159//protein phosphatase type 2A complex;GO:0005634//nucleus 160 sp|Q08397|LOXL1_HUMAN Lysyl oxidase homolog 1 OS=Homo sapiens GN=LOXL1 PE=1 SV=2 66797 MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSEYVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFGFGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS 218 8.7 - 16 16 5 5 1.899 2.081 1.989 10 10 10 * * * 1.989666667 0.091001831 sp|Q08397|LOXL1_HUMAN 100 4.00E-123 gi|119598345|gb|EAW77939.1| hCG40821 [Homo sapiens] 100 0 sp|Q08397|LOXL1_HUMAN Lysyl oxidase homolog 1 OS=Homo sapiens GN=LOXL1 PE=2 SV=2 99.56 1.00E-133 G7P930 G7P930_MACFA Lysyl oxidase-like protein 1 (Fragment) OS=Macaca fascicularis GN=EGM_16123 PE=4 SV=1 - - - - - - - K14678|1|0.0|956|hsa:4016|lysyl oxidase-like protein 1 [EC:1.4.3.-] GO:0018277//protein deamination;GO:0055114//oxidation-reduction process GO:0005507//copper ion binding;GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0005515//protein binding GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 161 sp|Q14019|COTL1_HUMAN Coactosin-like protein OS=Homo sapiens GN=COTL1 PE=1 SV=3 20308 MATKIDKEACRAAYNLVRDDGSAVIWVTFKYDGSTIVPGEQGAEYQHFIQQCTDDVRLFAFVRFTTGDAMSKRSKFALITWIGENVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEEDFIKSELKKAGGANYDAQTE 164 18.3 - 16 16 3 3 1.401 1.162 1.027 6 6 6 - - - 1.196666667 0.18939465 sp|Q14019|COTL1_HUMAN 100 6.00E-62 gi|395748168|ref|XP_002826758.2| PREDICTED: coactosin-like protein, partial [Pongo abelii] 100 4.00E-79 sp|Q14019|COTL1_HUMAN Coactosin-like protein OS=Homo sapiens GN=COTL1 PE=1 SV=3 100 1.00E-33 H3BT58 H3BT58_HUMAN Coactosin-like protein OS=Homo sapiens GN=COTL1 PE=4 SV=1 - - - - - - - - GO:0050832//defense response to fungus GO:0003779//actin binding;GO:0019899//enzyme binding GO:0005856//cytoskeleton;GO:0005737//cytoplasm 162 sp|P07996|TSP1_HUMAN Thrombospondin-1 OS=Homo sapiens GN=THBS1 PE=1 SV=2 150327 MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAGGRLGLFVFSQEMVFFSDLKYECRDP 2018 26.1 - 143 5 27 1 0.294 0.334 0.189 4 4 3 * * * 0.272333333 0.074888806 sp|P07996|TSP1_HUMAN 100 0 gi|118600432|gb|AAH28145.1| THBS1 protein [Homo sapiens] 100 0 sp|P07996|TSP1_HUMAN Thrombospondin-1 OS=Homo sapiens GN=THBS1 PE=1 SV=2 100 0 A0PJG0 A0PJG0_HUMAN THBS1 protein (Fragment) OS=Homo sapiens GN=THBS1 PE=2 SV=1 - - - - - - - K04659|1|0.0|2225|ptr:453319|thrombospondin GO:0016525//negative regulation of angiogenesis;GO:2000462//positive regulation of eukaryotic cell surface binding;GO:0006955//immune response;GO:0043032//positive regulation of macrophage activation;GO:0043652//engulfment of apoptotic cell;GO:0003417//growth plate cartilage development;GO:0045727//positive regulation of translation;GO:0009749//response to glucose stimulus;GO:0002581//negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0045766//positive regulation of angiogenesis;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0032695//negative regulation of interleukin-12 production;GO:0018149//peptide cross-linking;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0010763//positive regulation of fibroblast migration;GO:0051895//negative regulation of focal adhesion assembly;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0030168//platelet activation;GO:0051918//negative regulation of fibrinolysis;GO:0010757//negative regulation of plasminogen activation;GO:0001666//response to hypoxia;GO:0034605//cellular response to heat;GO:0051592//response to calcium ion;GO:0010811//positive regulation of cell-substrate adhesion;GO:0010748//negative regulation of plasma membrane long-chain fatty acid transport;GO:0001937//negative regulation of endothelial cell proliferation;GO:0032026//response to magnesium ion;GO:0002576//platelet degranulation;GO:0010754//negative regulation of cGMP-mediated signaling;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0032570//response to progesterone stimulus;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0002544//chronic inflammatory response;GO:0007050//cell cycle arrest;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0002605//negative regulation of dendritic cell antigen processing and presentation;GO:0051897//positive regulation of protein kinase B signaling cascade;GO:0000187//activation of MAPK activity;GO:0042493//response to drug;GO:0002040//sprouting angiogenesis;GO:0010759//positive regulation of macrophage chemotaxis;GO:0006917//induction of apoptosis GO:0070051//fibrinogen binding;GO:0008201//heparin binding;GO:0070052//collagen V binding;GO:0005178//integrin binding;GO:0017134//fibroblast growth factor binding;GO:0001968//fibronectin binding;GO:0042802//identical protein binding;GO:0030169//low-density lipoprotein particle binding;GO:0001786//phosphatidylserine binding;GO:0043499//eukaryotic cell surface binding;GO:0050431//transforming growth factor beta binding;GO:0005509//calcium ion binding;GO:0043394//proteoglycan binding;GO:0043236//laminin binding GO:0005577//fibrinogen complex;GO:0009897//external side of plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0031012//extracellular matrix 163 tr|Q53FR4|Q53FR4_HUMAN Vacuolar protein sorting 35 variant (Fragment) OS=Homo sapiens PE=2 SV=1 106719 MPTTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVKSFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSMDFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRLALFAHREDGPGIPADIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRVDYVDKVLETTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLKLKHFHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQDQVDSIMNLVSTLIQDQPDQPVEDPDPEDFADEQSLVGRFIHLLRSEDPDQQYLISNTARKHFGAGGNQRIRFTLPPLVFAAYQLAFRYKENSKVDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMKCFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRLRRESPESEGPIYEGLIL 129 6.7 1 10 10 5 5 1.164 0.635 0.845 4 4 4 - - - 0.881333333 0.266365038 tr|Q53FR4|Q53FR4_HUMAN 100 0 gi|345308557|ref|XP_001520331.2| PREDICTED: vacuolar protein sorting-associated protein 35, partial [Ornithorhynchus anatinus] 99.87 0 sp|Q96QK1|VPS35_HUMAN Vacuolar protein sorting-associated protein 35 OS=Homo sapiens GN=VPS35 PE=1 SV=2 100 2.00E-105 Q3TUV7 Q3TUV7_MOUSE Putative uncharacterized protein (Fragment) OS=Mus musculus GN=Vps35 PE=2 SV=1 - - - - - - - - GO:0015031//protein transport;GO:0008219//cell death;GO:0042147//retrograde transport, endosome to Golgi GO:0005515//protein binding GO:0016020//membrane;GO:0005829//cytosol;GO:0005768//endosome 164 tr|B4E1D8|B4E1D8_HUMAN cDNA FLJ51597, highly similar to C4b-binding protein alpha chain OS=Homo sapiens PE=2 SV=1 71792 MDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCTNLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRFSAICQGDGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSHWSAPAPQCKALCRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGKRLMQCLPNPEDVKMALEVYKLSLEIEQLELQRDSARQSTLDKEL 123 8.4 2 9 9 4 4 0.628 2.23 0.731 5 5 5 * * - 1.196333333 0.896661772 tr|B4E1D8|B4E1D8_HUMAN 100 0 gi|194383558|dbj|BAG64750.1| unnamed protein product [Homo sapiens] 99.81 0 sp|P04003|C4BPA_HUMAN C4b-binding protein alpha chain OS=Homo sapiens GN=C4BPA PE=1 SV=2 100 0 B4E1D8 B4E1D8_HUMAN cDNA FLJ51597, highly similar to C4b-binding protein alpha chain OS=Homo sapiens PE=2 SV=1 - - - - - - - K04002|1|0.0|1110|hsa:722|complement component 4 binding protein, alpha GO:0045087//innate immune response;GO:0030449//regulation of complement activation;GO:0006958//complement activation, classical pathway GO:0005515//protein binding GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005576//extracellular region 165 sp|Q15417|CNN3_HUMAN Calponin-3 OS=Homo sapiens GN=CNN3 PE=1 SV=1 44167 MTHFNKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGPNFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNSTISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQAEYPDEYHGEYQDDYPRDYQYSDQGIDY 176 15.8 - 11 6 4 3 1.265 1.602 0.828 3 3 3 - - - 1.231666667 0.388075165 sp|Q15417|CNN3_HUMAN 100 3.00E-61 gi|138752628|emb|CAM32246.1| calponin 3, acidic [Sus scrofa] 100 0 sp|Q15417|CNN3_HUMAN Calponin-3 OS=Homo sapiens GN=CNN3 PE=1 SV=1 100 6.00E-41 A4H2I3 A4H2I3_PIG Calponin 3, acidic (Fragment) OS=Sus scrofa GN=CNN3 PE=4 SV=1 ECU03g1150 75.5 1.00E-13 COG5199 Calponin Z Cytoskeleton ; K06084|1|8e-12|71.6|xla:100037140|F-box protein 20!K13710|5|2e-09|63.5|dre:553493|Rho guanine nucleotide exchange factor 7 GO:0031032//actomyosin structure organization;GO:0032780//negative regulation of ATPase activity;GO:0006939//smooth muscle contraction GO:0008017//microtubule binding;GO:0030674//protein binding, bridging;GO:0005516//calmodulin binding;GO:0030172//troponin C binding;GO:0003779//actin binding;GO:0005523//tropomyosin binding GO:0005874//microtubule;GO:0043025//neuronal cell body;GO:0005884//actin filament;GO:0014069//postsynaptic density 166 tr|C9JL85|C9JL85_HUMAN Myotrophin OS=Homo sapiens GN=MTPN PE=1 SV=1 8191 MCDKEFMWALKNGDLDEVKDYVAKGADKTVKGPDGLTAFEATDNQAIKALLQ 146 32.7 1 3 3 1 1 0.733 0.558 0.417 3 3 3 - - * 0.569333333 0.158304559 tr|C9JL85|C9JL85_HUMAN 100 1.00E-06 gi|444728352|gb|ELW68810.1| Myotrophin [Tupaia chinensis] 82.35 7.00E-09 sp|P58546|MTPN_HUMAN Myotrophin OS=Homo sapiens GN=MTPN PE=1 SV=2 100 1.00E-21 C9JL85 C9JL85_HUMAN Myotrophin OS=Homo sapiens GN=MTPN PE=4 SV=1 - - - - - - - - GO:0030307//positive regulation of cell growth;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010557//positive regulation of macromolecule biosynthetic process;GO:0006584//catecholamine metabolic process;GO:2000812//regulation of barbed-end actin filament capping;GO:0051146//striated muscle cell differentiation;GO:0043403//skeletal muscle tissue regeneration;GO:0006417//regulation of translation;GO:0016202//regulation of striated muscle tissue development;GO:0051247//positive regulation of protein metabolic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0021707//cerebellar granule cell differentiation GO:0005515//protein binding GO:0005829//cytosol;GO:0030424//axon;GO:0008290//F-actin capping protein complex;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus 167 tr|Q6FHE1|Q6FHE1_HUMAN FST protein OS=Homo sapiens GN=FST PE=2 SV=1 45264 MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGRLSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPEKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYCNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLVYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCN 150 17.4 1 5 5 4 4 0.883 1.219 1 5 5 4 - - - 1.034 0.17056084 tr|Q6FHE1|Q6FHE1_HUMAN 100 3.00E-177 gi|49456583|emb|CAG46612.1| FST [Homo sapiens] 99.05 8.00E-176 sp|P19883|FST_HUMAN Follistatin OS=Homo sapiens GN=FST PE=1 SV=2 100 8.00E-21 Q7TS59 Q7TS59_RAT Follistatin 288 variant (Fragment) OS=Rattus norvegicus GN=Fst PE=2 SV=1 - - - - - - - K04661|1|1e-177|622|ptr:461879|follistatin GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045596//negative regulation of cell differentiation;GO:0051798//positive regulation of hair follicle development;GO:0043616//keratinocyte proliferation;GO:0008585//female gonad development;GO:0007389//pattern specification process;GO:0002244//hematopoietic progenitor cell differentiation;GO:0031069//hair follicle morphogenesis;GO:0046882//negative regulation of follicle-stimulating hormone secretion;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0042475//odontogenesis of dentin-containing tooth;GO:0007276//gamete generation;GO:0030509//BMP signaling pathway GO:0004871//signal transducer activity;GO:0048185//activin binding;GO:0043395//heparan sulfate proteoglycan binding GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005634//nucleus 168 tr|B7ZLY3|B7ZLY3_HUMAN LTBP1 protein OS=Homo sapiens GN=LTBP1 PE=2 SV=1 175722 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPDISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE 332 9.2 3 15 15 8 8 2.34 4.021 2.755 12 12 11 - * * 3.038666667 0.875665652 tr|B7ZLY3|B7ZLY3_HUMAN 100 0 gi|219518146|gb|AAI44129.1| LTBP1 protein [Homo sapiens] 96.73 0 sp|Q14766|LTBP1_HUMAN Latent-transforming growth factor beta-binding protein 1 OS=Homo sapiens GN=LTBP1 PE=1 SV=4 100 0 B7ZLY3 B7ZLY3_HUMAN LTBP1 protein OS=Homo sapiens GN=LTBP1 PE=2 SV=1 - - - - - - - K08023|1|0.0|2690|hsa:4052|latent transforming growth factor beta binding protein GO:0035583//sequestering of TGFbeta in extracellular matrix GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005509//calcium ion binding;GO:0019838//growth factor binding GO:0005578//proteinaceous extracellular matrix 169 sp|Q14204|DYHC1_HUMAN Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens GN=DYNC1H1 PE=1 SV=5 624245 MSEPGGGGGEDGSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGEAPAALEAALEEKSALEQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIKRTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGVTGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLCTE 213 4.4 - 21 21 19 19 0.965 0.692 0.566 7 8 8 - * * 0.741 0.203963232 sp|Q14204|DYHC1_HUMAN 100 0 gi|71891782|dbj|BAA20783.3| KIAA0325 protein [Homo sapiens] 100 0 sp|Q14204|DYHC1_HUMAN Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens GN=DYNC1H1 PE=1 SV=5 100 2.00E-127 G3QD10 G3QD10_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=DYNC1H1 PE=4 SV=1 YKR054c 1861 0 COG5245 Dynein, heavy chain Z Cytoskeleton ; K10413|1|0.0|9458|hsa:1778|dynein heavy chain 1, cytosolic GO:0006810//transport;GO:0007052//mitotic spindle organization;GO:0034063//stress granule assembly;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0008219//cell death;GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement;GO:0000086//G2/M transition of mitotic cell cycle;GO:0033962//cytoplasmic mRNA processing body assembly GO:0005515//protein binding;GO:0003777//microtubule motor activity;GO:0042623//ATPase activity, coupled;GO:0005524//ATP binding GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005874//microtubule;GO:0005813//centrosome;GO:0005868//cytoplasmic dynein complex 170 sp|Q9BXJ0|C1QT5_HUMAN Complement C1q tumor necrosis factor-related protein 5 OS=Homo sapiens GN=C1QTNF5 PE=1 SV=1 >tr|A0A024R3F8|A0A024R3F8_HUMAN C1q and tumor necrosis factor related protein 5, isoform CRA_a OS=Homo sapiens GN=C1QTNF5 PE=4 SV=1 27887 MRPLLVLLLLGLAAGSPPLDDNKIPSLCPGHPGLPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGDPGPRGEAGPAGPTGPAGECSVPPRSAFSAKRSESRVPPPSDAPLPFDRVLVNEQGHYDAVTGKFTCQVPGVYYFAVHATVYRASLQFDLVKNGESIASFFQFFGGWPKPASLSGGAMVRLEPEDQVWVQVGVGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA 678 23.5 - 23 23 4 4 1.752 2.604 1.317 13 10 12 * * - 1.891 0.654662508 sp|Q9BXJ0|C1QT5_HUMAN 100 2.00E-81 gi|14149712|ref|NP_056460.1| complement C1q tumor necrosis factor-related protein 5 precursor [Homo sapiens] >gi|20177861|sp|Q9BXJ0.1|C1QT5_HUMAN RecName: Full=Complement C1q tumor necrosis factor-related protein 5; Flags: Precursor >gi|13274528|gb|AAK17965.1|AF329841_1 complement-c1q tumor necrosis factor-related protein [Homo sapiens] >gi|37181891|gb|AAQ88749.1| CTRP5 [Homo sapiens] >gi|82173742|emb|CAH93522.1| C1Q TNF related protein 5 [Homo sapiens] >gi|119587885|gb|EAW67481.1| C1q and tumor necrosis factor related protein 5, isoform CRA_a [Homo sapiens] >gi|119587886|gb|EAW67482.1| C1q and tumor necrosis factor related protein 5, isoform CRA_a [Homo sapiens] >gi|167887610|gb|ACA06014.1| complement C1q tumor necrosis factor-related protein 5 precursor variant 3 [Homo sapiens] 100 2.00E-82 sp|Q9BXJ0|C1QT5_HUMAN Complement C1q tumor necrosis factor-related protein 5 OS=Homo sapiens GN=C1QTNF5 PE=1 SV=1 100 7.00E-81 H2RBZ1 H2RBZ1_PANTR Uncharacterized protein OS=Pan troglodytes GN=C1QTNF5 PE=4 SV=1 - - - - - - - K07296|1|2e-21|102|tgu:100217624|adiponectin - - 171 tr|A0A0A0MTR1|A0A0A0MTR1_HUMAN Cadherin-13 OS=Homo sapiens GN=CDH13 PE=4 SV=1 87820 SQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPYFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVLLLSLFSLACL 197 6.7 2 14 14 4 4 0.662 0.704 0.97 6 6 6 - * - 0.778666667 0.167024948 tr|A0A0A0MTR1|A0A0A0MTR1_HUMAN 100 0 gi|333944015|ref|NP_001207417.1| cadherin-13 isoform 2 [Homo sapiens] 100 0 sp|P55290|CAD13_HUMAN Cadherin-13 OS=Homo sapiens GN=CDH13 PE=1 SV=1 100 0 H0YH43 H0YH43_HUMAN Cadherin-13 OS=Homo sapiens GN=CDH13 PE=4 SV=1 - - - - - - - K06808|1|0.0|1395|hsa:1012|cadherin 13, H-cadherin GO:0030100//regulation of endocytosis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0043542//endothelial cell migration;GO:0016339//calcium-dependent cell-cell adhesion;GO:0030032//lamellipodium assembly;GO:0007266//Rho protein signal transduction;GO:0034332//adherens junction organization;GO:0050927//positive regulation of positive chemotaxis;GO:0055096//low-density lipoprotein particle mediated signaling;GO:0043616//keratinocyte proliferation;GO:0007162//negative regulation of cell adhesion;GO:0002040//sprouting angiogenesis;GO:0050850//positive regulation of calcium-mediated signaling;GO:0008285//negative regulation of cell proliferation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0034329//cell junction assembly;GO:0051668//localization within membrane;GO:0007156//homophilic cell adhesion;GO:0001954//positive regulation of cell-matrix adhesion;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0016601//Rac protein signal transduction;GO:0030335//positive regulation of cell migration GO:0055100//adiponectin binding;GO:0045296//cadherin binding;GO:0005509//calcium ion binding;GO:0030169//low-density lipoprotein particle binding GO:0043005//neuron projection;GO:0005615//extracellular space;GO:0016021//integral to membrane;GO:0031225//anchored to membrane;GO:0005737//cytoplasm;GO:0005901//caveola 172 tr|A0A024R509|A0A024R509_HUMAN Arylsulfatase A, isoform CRA_a OS=Homo sapiens GN=ARSA PE=4 SV=1 57351 MSMGAPRSLLLALAAGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIPLLANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDGFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRSGKYKAHFFTQGSAHSDTTADPACHASSSLTAHEPPLLYDLSKDPGENYNLLGGVAGATPEVLQALKQLQLLKAQLDAAVTFGPSQVARGEDPALQICCHPGCTPRPACCHCPDPHA 99 4.7 2 3 3 1 1 --- 1.261 1.496 1 2 2 - - - 1.3785 0.166170094 tr|A0A024R509|A0A024R509_HUMAN 100 0 gi|33874703|gb|AAH14210.2| Arylsulfatase A [Homo sapiens] 99.8 0 sp|P15289|ARSA_HUMAN Arylsulfatase A OS=Homo sapiens GN=ARSA PE=1 SV=3 99.8 0 G2HJX6 G2HJX6_PANTR Arylsulfatase A OS=Pan troglodytes PE=2 SV=1 SMa1683 204 4.00E-52 COG3119 Arylsulfatase A and related enzymes P Inorganic ion transport and metabolism ; K01134|1|0.0|885|hsa:410|arylsulfatase A [EC:3.1.6.8] GO:0015700//arsenite transport;GO:0006644//phospholipid metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0043687//post-translational protein modification;GO:0007339//binding of sperm to zona pellucida;GO:0044281//small molecule metabolic process;GO:0071722//detoxification of arsenic-containing substance GO:0005509//calcium ion binding;GO:0015105//arsenite transmembrane transporter activity;GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0004065//arylsulfatase activity;GO:0004098//cerebroside-sulfatase activity GO:0005730//nucleolus;GO:0043202//lysosomal lumen;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane 173 sp|P01024|CO3_HUMAN Complement C3 OS=Homo sapiens GN=C3 PE=1 SV=2 >tr|V9HWA9|V9HWA9_HUMAN Epididymis secretory sperm binding protein Li 62p OS=Homo sapiens GN=HEL-S-62p PE=2 SV=1 223249 MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPLSITVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLARSNLDEDIIAEENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRCAEENCFIQKSDDKVTLEERLDKACEPGVDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGSDEVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGKDTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGCPN 1876 29 - 120 120 41 41 0.838 2.437 0.85 59 49 47 * * - 1.375 0.91973855 sp|P01024|CO3_HUMAN 100 0 gi|78101271|pdb|2A74|C Chain C, Human Complement Component C3c >gi|78101274|pdb|2A74|F Chain F, Human Complement Component C3c >gi|119390094|pdb|2ICE|C Chain C, Crig Bound To C3c >gi|119390098|pdb|2ICE|F Chain F, Crig Bound To C3c >gi|157835960|pdb|2QKI|C Chain C, Human C3c In Complex With The Inhibitor Compstatin >gi|157835963|pdb|2QKI|F Chain F, Human C3c In Complex With The Inhibitor Compstatin >gi|302148743|pdb|3L3O|F Chain F, Staphylococcal Complement Inhibitor (Scin) In Complex With Human Complement Component C3c >gi|302148745|pdb|3L3O|C Chain C, Staphylococcal Complement Inhibitor (Scin) In Complex With Human Complement Component C3c >gi|302148861|pdb|3NMS|C Chain C, Staphylococcal Complement Inhibitor (Scin) In Complex With Human Complement C3c >gi|305677900|pdb|3OHX|C Chain C, Molecular Basis For Complement Recognition And Inhibition Determined By Crystallographic Studies Of The Staphylococcal Complement Inhibitor (Scin) Bound To C3c And C3b >gi|305677904|pdb|3OHX|F Chain F, Molecular Basis For Complement Recognition And Inhibition Determined By Crystallographic Studies Of The Staphylococcal Complement Inhibitor (Scin) Bound To C3c And C3b 100 0 sp|P01024|CO3_HUMAN Complement C3 OS=Homo sapiens GN=C3 PE=1 SV=2 100 0 B4E216 B4E216_HUMAN Uncharacterized protein OS=Homo sapiens GN=C3 PE=2 SV=1 - - - - - - - K03990|1|0.0|3407|hsa:718|complement component 3 GO:0002507//tolerance induction;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0006958//complement activation, classical pathway;GO:0010828//positive regulation of glucose transport;GO:0051384//response to glucocorticoid stimulus;GO:0045766//positive regulation of angiogenesis;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0006957//complement activation, alternative pathway;GO:0007596//blood coagulation;GO:0001798//positive regulation of type IIa hypersensitivity;GO:0001934//positive regulation of protein phosphorylation;GO:0006935//chemotaxis;GO:0032026//response to magnesium ion;GO:0048639//positive regulation of developmental growth;GO:0032570//response to progesterone stimulus;GO:0001970//positive regulation of activation of membrane attack complex;GO:0010951//negative regulation of endopeptidase activity;GO:0050766//positive regulation of phagocytosis;GO:0010884//positive regulation of lipid storage;GO:0010866//regulation of triglyceride biosynthetic process;GO:0032355//response to estradiol stimulus;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway GO:0031715//C5L2 anaphylatoxin chemotactic receptor binding;GO:0048037//cofactor binding;GO:0008289//lipid binding;GO:0004866//endopeptidase inhibitor activity GO:0005615//extracellular space;GO:0005886//plasma membrane 174 sp|Q8WVQ1|CANT1_HUMAN Soluble calcium-activated nucleotidase 1 OS=Homo sapiens GN=CANT1 PE=1 SV=1 >tr|A0A024R8U8|A0A024R8U8_HUMAN Calcium activated nucleotidase 1, isoform CRA_b OS=Homo sapiens GN=CANT1 PE=4 SV=1 51618 MPVQLSEHPEWNESMHSLRISVGGLPVLASMTKAADPRFRPRWKVILTFFVGAAILWLLCSHRPAPGRPPTHNAHNWRLGQAPANWYNDTYPLSPPQRTPAGIRYRIAVIADLDTESRAQEENTWFSYLKKGYLTLSDSGDKVAVEWDKDHGVLESHLAEKGRGMELSDLIVFNGKLYSVDDRTGVVYQIEGSKAVPWVILSDGDGTVEKGFKAEWLAVKDERLYVGGLGKEWTTTTGDVVNENPEWVKVVGYKGSVDHENWVSNYNALRAAAGIQPPGYLIHESACWSDTLQRWFFLPRRASQERYSEKDDERKGANLLLSASPDFGDIAVSHVGAVVPTHGFSSFKFIPNTDDQIIVALKSEEDSGRVASYIMAFTLDGRFLLPETKIGSVKYEGIEFI 108 7.5 - 5 5 2 2 1.176 1.31 1.303 3 3 2 - * - 1.263 0.07542546 sp|Q8WVQ1|CANT1_HUMAN 100 0 gi|112491029|pdb|2H2N|A Chain A, Crystal Structure Of Human Soluble Calcium-activated Nucleotidase (scan) With Calcium Ion >gi|112491030|pdb|2H2N|B Chain B, Crystal Structure Of Human Soluble Calcium-activated Nucleotidase (scan) With Calcium Ion 100 0 sp|Q8WVQ1|CANT1_HUMAN Soluble calcium-activated nucleotidase 1 OS=Homo sapiens GN=CANT1 PE=1 SV=1 99.25 0 G3QJ21 G3QJ21_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=CANT1 PE=4 SV=1 - - - - - - - K12304|1|0.0|827|hsa:124583|soluble calcium-activated nucleotidase 1 [EC:3.6.1.6] GO:0030166//proteoglycan biosynthetic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB cascade;GO:0009191//ribonucleoside diphosphate catabolic process GO:0045134//uridine-diphosphatase activity;GO:0005509//calcium ion binding;GO:0004871//signal transducer activity;GO:0004382//guanosine-diphosphatase activity GO:0032580//Golgi cisterna membrane;GO:0016021//integral to membrane;GO:0005789//endoplasmic reticulum membrane 175 tr|B0YIW2|B0YIW2_HUMAN Apolipoprotein C-III OS=Homo sapiens GN=APOC3 PE=1 SV=1 14994 MGTWGAPHRTLPCRNRGAMQPRVLLVVALLALLASARASEAEDASLLSFMQGYMKHATKTAKDALSSVQESQVAQQARGWVTDGFSSLKDYWSTVKDKFSEFWDLDPEVRPTSAVAA 269 23.1 1 12 12 2 2 0.811 2.361 0.755 6 4 5 * - - 1.309 0.911488892 tr|B0YIW2|B0YIW2_HUMAN 100 6.00E-26 gi|4557323|ref|NP_000031.1| apolipoprotein C-III precursor [Homo sapiens] >gi|114026|sp|P02656.1|APOC3_HUMAN RecName: Full=Apolipoprotein C-III; Short=Apo-CIII; Short=ApoC-III; AltName: Full=Apolipoprotein C3; Flags: Precursor >gi|28728|emb|CAA25644.1| pre-apolipoprotein CIII [Homo sapiens] >gi|178827|gb|AAA51760.1| apolipoprotein C-III precursor [Homo sapiens] >gi|178829|gb|AAA51761.1| apolipoprotein C-III precursor [Homo sapiens] >gi|296632|emb|CAA25648.1| apo CIII [Homo sapiens] >gi|471838|gb|AAB59515.1| preapolipoprotein C-III [Homo sapiens] >gi|671881|emb|CAA26895.1| apolipoprotein [Homo sapiens] >gi|757913|emb|CAA25233.1| apoCIII protein [Homo sapiens] >gi|20379765|gb|AAH27977.1| Apolipoprotein C-III [Homo sapiens] >gi|37499463|gb|AAQ91810.1| apolipoprotein C-III [Homo sapiens] >gi|45593394|gb|AAS68230.1| apolipoprotein C-III [Homo sapiens] >gi|115529055|gb|AAI21082.1| Apolipoprotein C-III [Homo sapiens] >gi|119587676|gb|EAW67272.1| apolipoprotein C-III, isoform CRA_a [Homo sapiens] >gi|119587677|gb|EAW67273.1| apolipoprotein C-III, isoform CRA_a [Homo sapiens] >gi|126631316|gb|AAI34420.1| Apolipoprotein C-III [Homo sapiens] >gi|167887492|gb|ACA05940.1| apolipoprotein C-III precursor variant 2 [Homo sapiens] >gi|167887494|gb|ACA05942.1| apolipoprotein C-III precursor variant 3 [Homo sapiens] 100 7.00E-27 sp|P02656|APOC3_HUMAN Apolipoprotein C-III OS=Homo sapiens GN=APOC3 PE=1 SV=1 100 3.00E-25 A3KPE2 A3KPE2_HUMAN Apolipoprotein C-III OS=Homo sapiens GN=APOC3 PE=4 SV=1 - - - - - - - K08759|1|6e-27|119|hsa:345|apolipoprotein C-III GO:0007186//G-protein coupled receptor signaling pathway;GO:0033344//cholesterol efflux;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0010903//negative regulation of very-low-density lipoprotein particle remodeling;GO:0060621//negative regulation of cholesterol import;GO:0032488//Cdc42 protein signal transduction;GO:0008203//cholesterol metabolic process;GO:0043691//reverse cholesterol transport;GO:0034379//very-low-density lipoprotein particle assembly;GO:0042157//lipoprotein metabolic process;GO:0010987//negative regulation of high-density lipoprotein particle clearance;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0034375//high-density lipoprotein particle remodeling;GO:0051005//negative regulation of lipoprotein lipase activity;GO:0070328//triglyceride homeostasis;GO:0033700//phospholipid efflux;GO:0010897//negative regulation of triglyceride catabolic process;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0034382//chylomicron remnant clearance;GO:0006642//triglyceride mobilization;GO:0010916//negative regulation of very-low-density lipoprotein particle clearance;GO:0042632//cholesterol homeostasis GO:0015485//cholesterol binding;GO:0005543//phospholipid binding;GO:0055102//lipase inhibitor activity;GO:0070653//high-density lipoprotein particle receptor binding GO:0042627//chylomicron;GO:0034366//spherical high-density lipoprotein particle;GO:0034361//very-low-density lipoprotein particle;GO:0034363//intermediate-density lipoprotein particle 176 tr|A0A087X1J7|A0A087X1J7_HUMAN Glutathione peroxidase OS=Homo sapiens GN=GPX3 PE=3 SV=1 30481 MARLLQASCLLSLLLAGFVSQSRGQEKSKMDCHGGISGTIYEYGALTIDGEEYIPFKQYAGKYVLFVNVASYGLTGQYIELNALQEELAPFGLVILGFPCNQFGKQEPGENSEILPTLKYVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTSELLGTSDRLFWEPMKVHDIRWNFEKFLVGPDGIPIMRWHHRTTVSNVKMDILSYMRRQAALGVKRK 116 19.1 1 7 7 3 3 0.544 --- 0.038 2 - 2 - - - 0.291 0.357796031 tr|A0A087X1J7|A0A087X1J7_HUMAN 100 1.00E-81 gi|404108|dbj|BAA03864.1| plasma glutathione peroxidase [Homo sapiens] 99.56 1.00E-120 sp|P22352|GPX3_HUMAN Glutathione peroxidase 3 OS=Homo sapiens GN=GPX3 PE=1 SV=2 100 1.00E-120 H2R580 H2R580_PANTR Glutathione peroxidase OS=Pan troglodytes GN=GPX3 PE=3 SV=1 STM1341 101 1.00E-21 COG0386 Glutathione peroxidase O Posttranslational modification, protein turnover, chaperones ; K00432|1|1e-120|432|ptr:471703|glutathione peroxidase [EC:1.11.1.9] GO:0042744//hydrogen peroxide catabolic process;GO:0055114//oxidation-reduction process;GO:0051412//response to corticosterone stimulus;GO:0007565//female pregnancy;GO:0006749//glutathione metabolic process;GO:0006982//response to lipid hydroperoxide;GO:0014070//response to organic cyclic compound;GO:0002238//response to molecule of fungal origin;GO:0042493//response to drug;GO:0051289//protein homotetramerization;GO:0010269//response to selenium ion GO:0004602//glutathione peroxidase activity;GO:0008134//transcription factor binding;GO:0043295//glutathione binding;GO:0008430//selenium binding GO:0005615//extracellular space 177 tr|B4DY28|B4DY28_HUMAN cDNA FLJ61189, highly similar to Cysteine and glycine-rich protein 1 OS=Homo sapiens PE=2 SV=1 27880 MPNWGGGKKCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYCKSCYGKKYGPKGYGYGQGAGTLSTDKGESLGIKHEEAPGHRPTTNPNASKFAQKIGGSERCPRCSQAVYAAEKSWHKACFRCAKCGKGLESTTLADKDGEIYCKGCYAKNFGPKGFGFGQGAGALVHSE 805 42.8 2 28 28 6 6 0.551 0.605 0.482 25 26 25 * - * 0.546 0.061652251 tr|B4DY28|B4DY28_HUMAN 100 3.00E-56 gi|62089098|dbj|BAD92993.1| cysteine and glycine-rich protein 1 variant [Homo sapiens] 96.89 8.00E-78 sp|P21291|CSRP1_HUMAN Cysteine and glycine-rich protein 1 OS=Homo sapiens GN=CSRP1 PE=1 SV=3 100 1.00E-55 Q59EQ5 Q59EQ5_HUMAN Cysteine and glycine-rich protein 1 variant (Fragment) OS=Homo sapiens PE=2 SV=1 - - - - - - - K09377|1|4e-81|300|ptr:457621|cysteine and glycine-rich protein GO:0007399//nervous system development;GO:0030036//actin cytoskeleton organization GO:0046872//metal ion binding;GO:0005515//protein binding GO:0015629//actin cytoskeleton 178 sp|P09382|LEG1_HUMAN Galectin-1 OS=Homo sapiens GN=LGALS1 PE=1 SV=2 17786 MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD 1515 43.7 - 81 81 5 5 0.764 0.667 0.675 43 45 42 * * * 0.702 0.053842363 sp|P09382|LEG1_HUMAN 100 3.00E-74 gi|4504981|ref|NP_002296.1| galectin-1 [Homo sapiens] >gi|184228|gb|AAB00777.1| 14 kDa beta-galactoside-binding lectin [Homo sapiens] >gi|307122|gb|AAA36170.1| lectin precursor [Homo sapiens] >gi|4377694|emb|CAA33328.1| 14 kDa beta-galactoside-binding lectin [Homo sapiens] >gi|12804557|gb|AAH01693.1| Lectin, galactoside-binding, soluble, 1 [Homo sapiens] >gi|18088370|gb|AAH20675.1| Lectin, galactoside-binding, soluble, 1 [Homo sapiens] >gi|30582389|gb|AAP35421.1| lectin, galactoside-binding, soluble, 1 (galectin 1) [Homo sapiens] >gi|47678553|emb|CAG30397.1| LGALS1 [Homo sapiens] >gi|119580582|gb|EAW60178.1| lectin, galactoside-binding, soluble, 1 (galectin 1) [Homo sapiens] >gi|169635015|gb|ACA58297.1| beta-galactoside-binding lectin precursor [Homo sapiens] 100 3.00E-75 sp|P09382|LEG1_HUMAN Galectin-1 OS=Homo sapiens GN=LGALS1 PE=1 SV=2 100 1.00E-73 H2QLM5 H2QLM5_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000100097 PE=4 SV=1 - - - - - - - K06830|1|3e-75|279|hsa:3956|galectin-1 GO:0071333//cellular response to glucose stimulus;GO:0042981//regulation of apoptotic process;GO:0033555//multicellular organismal response to stress;GO:0071407//cellular response to organic cyclic compound;GO:0045445//myoblast differentiation;GO:0034120//positive regulation of erythrocyte aggregation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB cascade;GO:0010812//negative regulation of cell-substrate adhesion;GO:0048678//response to axon injury;GO:0042493//response to drug;GO:0010977//negative regulation of neuron projection development GO:0004871//signal transducer activity;GO:0043236//laminin binding;GO:0016936//galactoside binding;GO:0001948//glycoprotein binding;GO:0030395//lactose binding;GO:0042803//protein homodimerization activity GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0005578//proteinaceous extracellular matrix;GO:0005634//nucleus 179 tr|B2RBF5|B2RBF5_HUMAN cDNA, FLJ95483, highly similar to Homo sapiens chitobiase, di-N-acetyl- (CTBS), mRNA OS=Homo sapiens PE=2 SV=1 51447 MSRPQLRRWRLVSSPPSGVPGLALLALLALLALRLAAGTDCPCPEPELCRPIRHHPDFEVFVFDVGQKTWKSYDWSQITTVATFGKYDSELMCYAHSKGARVVLKGDVSLKDIIDPAFRASWIAQKLNLAKTQYMDGINIDIEQEVNCLSPEYDALTALVKETTDSFHREIEGSQVTFDVAWSPKNIDRRCYNYTGIADACDFLFVMSYDEQSQIWSECIAAANAPYNQTLTGYNDYIKMSINPKKFVMGVPWYGYDYTCLNLSEDHVCTIAKVPFRGAPCSDAAGRQVPYKTIMKQINSSISGNLWDKDQRAPYYNYKDPAGHFHQVWYDNPQSISLKATYIQNYRLRGIGMWNANCLDYSGDAVAKQQTEEMWEVLKPKLLQR 75 3.9 3 3 3 1 1 0.976 1.03 1.264 2 2 2 - - - 1.09 0.15308821 tr|B2RBF5|B2RBF5_HUMAN 100 0 gi|189054429|dbj|BAG37202.1| unnamed protein product [Homo sapiens] 99.74 0 sp|Q01459|DIAC_HUMAN Di-N-acetylchitobiase OS=Homo sapiens GN=CTBS PE=1 SV=1 100 0 B2RBF5 B2RBF5_HUMAN cDNA, FLJ95483, highly similar to Homo sapiens chitobiase, di-N-acetyl- (CTBS), mRNA OS=Homo sapiens PE=2 SV=1 BS_ydhD 80.1 6.00E-15 COG3858 Predicted glycosyl hydrolase R General function prediction only ; K12310|1|0.0|769|hsa:1486|Di-N-acetylchitobiase [EC:3.2.1.-] GO:0006032//chitin catabolic process;GO:0009313//oligosaccharide catabolic process GO:0004568//chitinase activity;GO:0043169//cation binding GO:0005764//lysosome 180 tr|A0A087X1H6|A0A087X1H6_HUMAN Hsc70-interacting protein OS=Homo sapiens GN=ST13 PE=4 SV=1 34723 MIKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASAMLKEVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARRQSGAQYGSFPGGFPGGMPGNFPGGMPGMGGGMPGMAGMPGLNEILSDPEVLAAMQDPEVMVAFQDVAQNPANMSKYQSNPKVMNLISKLSAKFGGQA 247 24 7 15 15 5 5 1.528 1.525 1.768 12 12 12 * * * 1.607 0.139438158 tr|A0A087X1H6|A0A087X1H6_HUMAN 100 3.00E-63 gi|113197796|gb|AAI21109.1| ST13 protein [Homo sapiens] >gi|113197838|gb|AAI21108.1| ST13 protein [Homo sapiens] 100 3.00E-93 sp|P50502|F10A1_HUMAN Hsc70-interacting protein OS=Homo sapiens GN=ST13 PE=1 SV=2 100 2.00E-91 Q1XBU6 Q1XBU6_HUMAN Aging-associated protein 14b OS=Homo sapiens PE=2 SV=1 FN1787 58.9 7.00E-09 COG0457 FOG: TPR repeat R General function prediction only ; K09560|1|1e-93|342|mcc:705664|suppressor of tumorigenicity protein 13 GO:0006457//protein folding GO:0030674//protein binding, bridging GO:0005737//cytoplasm 181 sp|Q07960|RHG01_HUMAN Rho GTPase-activating protein 1 OS=Homo sapiens GN=ARHGAP1 PE=1 SV=1 59892 MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDPSGL 86 8.2 - 4 4 3 3 0.603 1.031 --- 2 2 1 - - - 0.817 0.302641702 sp|Q07960|RHG01_HUMAN 100 3.00E-107 gi|3402094|pdb|1AM4|A Chain A, Complex Between Cdc42hs.Gmppnp And P50 Rhogap (H. Sapiens) >gi|3402096|pdb|1AM4|B Chain B, Complex Between Cdc42hs.Gmppnp And P50 Rhogap (H. Sapiens) >gi|3402098|pdb|1AM4|C Chain C, Complex Between Cdc42hs.Gmppnp And P50 Rhogap (H. Sapiens) 100 0 sp|Q07960|RHG01_HUMAN Rho GTPase-activating protein 1 OS=Homo sapiens GN=ARHGAP1 PE=1 SV=1 100 1.00E-100 E9PNR6 E9PNR6_HUMAN Rho GTPase-activating protein 1 (Fragment) OS=Homo sapiens GN=ARHGAP1 PE=4 SV=1 - - - - - - - K10360|1|6e-22|105|mmu:270163|myosin IX GO:0032855//positive regulation of Rac GTPase activity GO:0005070//SH3/SH2 adaptor activity;GO:0030675//Rac GTPase activator activity;GO:0017124//SH3 domain binding GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0001726//ruffle;GO:0005886//plasma membrane 182 tr|E9PKE3|E9PKE3_HUMAN Heat shock cognate 71 kDa protein OS=Homo sapiens GN=HSPA8 PE=1 SV=1 85723 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 1047 29.7 1 50 34 14 12 0.814 0.69 0.68 22 25 24 * * * 0.728 0.07464583 tr|E9PKE3|E9PKE3_HUMAN 99.83 0 gi|63101351|gb|AAH94900.1| Hspa8 protein [Mus musculus] 96.9 0 sp|P11142|HSP7C_HUMAN Heat shock cognate 71 kDa protein OS=Homo sapiens GN=HSPA8 PE=1 SV=1 100 0 E9PKE3 E9PKE3_HUMAN Heat shock cognate 71 kDa protein OS=Homo sapiens GN=HSPA8 PE=3 SV=1 SPAC13G7.02c 933 0 COG0443 Molecular chaperone O Posttranslational modification, protein turnover, chaperones ; K03283|1|0.0|1125|ecb:100009679|heat shock 70kDa protein 1/8 GO:0016044//cellular membrane organization;GO:0007269//neurotransmitter secretion;GO:0006397//mRNA processing;GO:0045892//negative regulation of transcription, DNA-dependent;GO:0008380//RNA splicing;GO:0051726//regulation of cell cycle;GO:0019048//virus-host interaction;GO:0051085//chaperone mediated protein folding requiring cofactor;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006200//ATP catabolic process;GO:0006986//response to unfolded protein GO:0005102//receptor binding;GO:0043531//ADP binding;GO:0051082//unfolded protein binding;GO:0042623//ATPase activity, coupled;GO:0005524//ATP binding GO:0043005//neuron projection;GO:0042470//melanosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005681//spliceosomal complex;GO:0009986//cell surface;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0043025//neuronal cell body;GO:0070062//extracellular vesicular exosome;GO:0000974//Prp19 complex;GO:0008021//synaptic vesicle;GO:0005886//plasma membrane 183 tr|F2Z2K0|F2Z2K0_HUMAN NSFL1 cofactor p47 OS=Homo sapiens GN=NSFL1C PE=1 SV=1 34822 MAAERQEALREFVAVTGAEEDRARFFLESAGWDLQIALASFYEDGGDEDIVTISQATPSSVSRGTAPSDNRVTSFRDLIHDQDEDEEEEEGQRFYAGGSERSGQQIVGPPRKKSPNELVDDLFKGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGEKRQHSSQDVHVVLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDFVKPKGAFKAFTGEGQKLGRLSCFPPFKPLFS 51 9.9 3 3 3 2 2 1.078 1.127 1.068 2 2 2 * - - 1.091 0.031575307 tr|F2Z2K0|F2Z2K0_HUMAN 100 9.00E-95 gi|119631033|gb|EAX10628.1| NSFL1 (p97) cofactor (p47), isoform CRA_c [Homo sapiens] 100 1.00E-145 sp|Q9UNZ2|NSF1C_HUMAN NSFL1 cofactor p47 OS=Homo sapiens GN=NSFL1C PE=1 SV=2 100 1.00E-129 H9FBJ4 H9FBJ4_MACMU NSFL1 cofactor p47 isoform a (Fragment) OS=Macaca mulatta GN=NSFL1C PE=2 SV=1 - - - - - - - K14012|1|2e-145|515|pon:100172420|UBX domain-containing protein 1 - GO:0008289//lipid binding GO:0005795//Golgi stack;GO:0005694//chromosome;GO:0005634//nucleus 184 tr|X6R9L0|X6R9L0_HUMAN DnaJ homolog subfamily C member 3 OS=Homo sapiens GN=DNAJC3 PE=1 SV=1 66937 MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN 67 7.3 1 4 4 3 3 0.769 1.574 1.017 3 3 3 - - - 1.12 0.412265691 tr|X6R9L0|X6R9L0_HUMAN 100 2.00E-69 gi|470641751|ref|XP_004325600.1| PREDICTED: dnaJ homolog subfamily C member 3-like [Tursiops truncatus] 89.88 0 sp|Q13217|DNJC3_HUMAN DnaJ homolog subfamily C member 3 OS=Homo sapiens GN=DNAJC3 PE=1 SV=1 99.78 0 F7H189 F7H189_MACMU Uncharacterized protein OS=Macaca mulatta GN=DNAJC3 PE=4 SV=1 MG019 84.7 3.00E-16 COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain O Posttranslational modification, protein turnover, chaperones ; K09523|1|0.0|835|hsa:5611|DnaJ homolog subfamily C member 3 GO:0009615//response to virus;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0006457//protein folding;GO:0006469//negative regulation of protein kinase activity;GO:0006987//activation of signaling protein activity involved in unfolded protein response GO:0016301//kinase activity;GO:0051087//chaperone binding;GO:0031072//heat shock protein binding;GO:0004860//protein kinase inhibitor activity;GO:0051082//unfolded protein binding;GO:0051787//misfolded protein binding GO:0005788//endoplasmic reticulum lumen;GO:0031205//endoplasmic reticulum Sec complex;GO:0005829//cytosol 185 sp|Q9NR12|PDLI7_HUMAN PDZ and LIM domain protein 7 OS=Homo sapiens GN=PDLIM7 PE=1 SV=1 59718 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFGAPPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTSTVLTRHSQPATPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAFSHV 237 10.1 - 13 13 4 4 1.223 0.878 0.504 7 6 5 - - * 0.868333333 0.35959746 sp|Q9NR12|PDLI7_HUMAN 100 1.00E-97 gi|54038515|gb|AAH84575.1| PDLIM7 protein [Homo sapiens] 100 0 sp|Q9NR12|PDLI7_HUMAN PDZ and LIM domain protein 7 OS=Homo sapiens GN=PDLIM7 PE=1 SV=1 100 3.00E-87 D6RF83 D6RF83_HUMAN PDZ and LIM domain protein 7 (Fragment) OS=Homo sapiens GN=PDLIM7 PE=4 SV=1 - - - - - - - K05760|1|1e-32|141|tca:658324|paxillin GO:0045669//positive regulation of osteoblast differentiation;GO:0030036//actin cytoskeleton organization;GO:0006898//receptor-mediated endocytosis;GO:0007275//multicellular organismal development GO:0008270//zinc ion binding;GO:0005515//protein binding GO:0001726//ruffle;GO:0001725//stress fiber;GO:0005925//focal adhesion;GO:0005737//cytoplasm 186 sp|Q15075|EEA1_HUMAN Early endosome antigen 1 OS=Homo sapiens GN=EEA1 PE=1 SV=2 216877 MLRRILQRTPGRVGSQGSDLDSSATPINTVDVNNESSSEGFICPQCMKSLGSADELFKHYEAVHDAGNDSGHGGESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKKILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDACFNDLQG 260 8 - 16 16 8 8 0.999 0.863 0.878 12 12 12 - * - 0.913333333 0.074567643 sp|Q15075|EEA1_HUMAN 100 0 gi|229462866|sp|Q15075.2|EEA1_HUMAN RecName: Full=Early endosome antigen 1; AltName: Full=Endosome-associated protein p162; AltName: Full=Zinc finger FYVE domain-containing protein 2 100 0 sp|Q15075|EEA1_HUMAN Early endosome antigen 1 OS=Homo sapiens GN=EEA1 PE=1 SV=2 100 5.00E-145 Q05D76 Q05D76_HUMAN EEA1 protein (Fragment) OS=Homo sapiens GN=EEA1 PE=2 SV=1 - - - - - - - K12478|1|0.0|2298|hsa:8411|early endosome antigen 1 GO:0006906//vesicle fusion;GO:0016189//synaptic vesicle to endosome fusion;GO:0045022//early endosome to late endosome transport GO:0005516//calmodulin binding;GO:0008270//zinc ion binding;GO:0005545//1-phosphatidylinositol binding;GO:0030742//GTP-dependent protein binding;GO:0042803//protein homodimerization activity GO:0005829//cytosol;GO:0031901//early endosome membrane;GO:0005969//serine-pyruvate aminotransferase complex;GO:0019897//extrinsic to plasma membrane 187 sp|P49327|FAS_HUMAN Fatty acid synthase OS=Homo sapiens GN=FASN PE=1 SV=3 302039 MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEALSRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQCPAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLARRVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVGDPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHSPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPPPAPAPHATLPRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGPEVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLSTDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAVLAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFEFVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEAQWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCTIIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSLAWDVPAAEDFPNGSGSPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLARALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQWDDPDPRLFDHPESPTPNPTEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRLLWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVVSRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQLCKGLVQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQVLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLLSPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVAALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESLFSRVSLRLVGLKKSFYGSTLFLCRRPTPQDSPIFLPVDDTSFRWVESLKGILADEDSSRPVWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGDLVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEEPEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGIRTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLLENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSAMERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTIVSGTLPQRMASCLEVLDLFLNQPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLRSLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLDSIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGSPTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAAVDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG 522 6.2 - 29 29 13 13 0.9 0.71 0.659 22 23 20 - - - 0.756333333 0.127005249 sp|P49327|FAS_HUMAN 100 0 gi|41872631|ref|NP_004095.4| fatty acid synthase [Homo sapiens] >gi|269849686|sp|P49327.3|FAS_HUMAN RecName: Full=Fatty acid synthase; Includes: RecName: Full=[Acyl-carrier-protein] S-acetyltransferase; Includes: RecName: Full=[Acyl-carrier-protein] S-malonyltransferase; Includes: RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase; Includes: RecName: Full=3-oxoacyl-[acyl-carrier-protein] reductase; Includes: RecName: Full=3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Includes: RecName: Full=Enoyl-[acyl-carrier-protein] reductase; Includes: RecName: Full=Oleoyl-[acyl-carrier-protein] hydrolase 100 0 sp|P49327|FAS_HUMAN Fatty acid synthase OS=Homo sapiens GN=FASN PE=1 SV=3 100 0 Q6PJJ3 Q6PJJ3_HUMAN FASN protein (Fragment) OS=Homo sapiens GN=FASN PE=2 SV=1 CAC3355 430 2.00E-119 COG3321 Polyketide synthase modules and related proteins Q Secondary metabolites biosynthesis, transport and catabolism ; K00665|1|0.0|4868|hsa:2194|fatty acid synthase, animal type [EC:2.3.1.85] GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0006633//fatty acid biosynthetic process;GO:0006084//acetyl-CoA metabolic process;GO:0031325//positive regulation of cellular metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0006112//energy reserve metabolic process;GO:0015939//pantothenate metabolic process GO:0008144//drug binding;GO:0031177//phosphopantetheine binding;GO:0004319//enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity;GO:0008270//zinc ion binding;GO:0004314//[acyl-carrier-protein] S-malonyltransferase activity;GO:0004316//3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity;GO:0004320//oleoyl-[acyl-carrier-protein] hydrolase activity;GO:0016296//palmitoyl-[acyl-carrier-protein] hydrolase activity;GO:0004317//3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity;GO:0070402//NADPH binding;GO:0004315//3-oxoacyl-[acyl-carrier-protein] synthase activity;GO:0042803//protein homodimerization activity;GO:0016295//myristoyl-[acyl-carrier-protein] hydrolase activity;GO:0004313//[acyl-carrier-protein] S-acetyltransferase activity GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0042470//melanosome;GO:0042587//glycogen granule;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane 188 tr|Q6FG99|Q6FG99_HUMAN RPLP1 protein OS=Homo sapiens GN=RPLP1 PE=2 SV=1 14051 MASVSELARIYSALILHDDEVTVTEDKINALIKAAGVNVEPFWPGLFAKALANVNIGSLICDVGAGGPAPAAGAAPAGGPAPSTAAAPAEEKKVEAKKEESEESDDDMGFGLFD 297 14 3 7 7 1 1 1.32 1.068 1.546 7 7 7 * - * 1.311333333 0.239117823 tr|Q6FG99|Q6FG99_HUMAN 100 2.00E-32 gi|49457412|emb|CAG47005.1| RPLP1 [Homo sapiens] 98.25 7.00E-29 sp|Q56K14|RLA1_BOVIN 60S acidic ribosomal protein P1 OS=Bos taurus GN=RPLP1 PE=3 SV=1 100 8.00E-32 Q6FG99 Q6FG99_HUMAN RPLP1 protein OS=Homo sapiens GN=RPLP1 PE=4 SV=1 SPBC3B9.13c 68.9 2.00E-12 COG2058 Ribosomal protein L12E/L44/L45/RPP1/RPP2 J Translation, ribosomal structure and biogenesis ; K02942|1|2e-29|127|aml:100478480|large subunit ribosomal protein LP1 GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006414//translational elongation;GO:0006415//translational termination;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003723//RNA binding;GO:0005515//protein binding GO:0022625//cytosolic large ribosomal subunit 189 tr|Q7RU04|Q7RU04_HUMAN Aminopeptidase B OS=Homo sapiens GN=RNPEP PE=4 SV=1 83927 MASGEHSPGSARPGGRCTPRRLRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSARPGEKRGPNKFFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQLVYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHSNVVNYVQQIVAPKGS 229 15.2 1 15 15 8 8 1.204 1.078 0.825 8 8 8 - - - 1.035666667 0.193013816 tr|Q7RU04|Q7RU04_HUMAN 100 0 gi|28317368|tpe|CAD29858.1| TPA: aminopeptidase B [Homo sapiens] 97.72 0 sp|Q9H4A4|AMPB_HUMAN Aminopeptidase B OS=Homo sapiens GN=RNPEP PE=1 SV=2 100 0 Q7RU04 Q7RU04_HUMAN Aminopeptidase B OS=Homo sapiens GN=RNPEP PE=4 SV=1 SPCC1322.05c 305 2.00E-82 COG0308 Aminopeptidase N E Amino acid transport and metabolism ; K01260|1|0.0|1291|hsa:6051|aminopeptidase B [EC:3.4.11.6] GO:0045776//negative regulation of blood pressure;GO:0019370//leukotriene biosynthetic process;GO:0006508//proteolysis;GO:0007568//aging;GO:0060041//retina development in camera-type eye GO:0005507//copper ion binding;GO:0042277//peptide binding;GO:0008270//zinc ion binding;GO:0050897//cobalt ion binding;GO:0070006//metalloaminopeptidase activity;GO:0004301//epoxide hydrolase activity GO:0030141//secretory granule;GO:0009897//external side of plasma membrane;GO:0043005//neuron projection;GO:0005615//extracellular space;GO:0005794//Golgi apparatus 190 sp|P54136|SYRC_HUMAN Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens GN=RARS PE=1 SV=2 93165 MDVLVSECSARLLQQEEEIKSLTAEIDRLKNCGCLGASPNLEQLQEENLKLKYRLNILRKSLQAERNKPTKNMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 54 5.3 - 3 3 3 3 0.616 0.421 --- 2 2 1 - - - 0.5185 0.137885822 sp|P54136|SYRC_HUMAN 100 0 gi|15149476|ref|NP_002878.2| arginine--tRNA ligase, cytoplasmic [Homo sapiens] >gi|20178331|sp|P54136.2|SYRC_HUMAN RecName: Full=Arginine--tRNA ligase, cytoplasmic; AltName: Full=Arginyl-tRNA synthetase; Short=ArgRS >gi|12653513|gb|AAH00528.1| Arginyl-tRNA synthetase [Homo sapiens] >gi|15779108|gb|AAH14619.1| Arginyl-tRNA synthetase [Homo sapiens] >gi|30583627|gb|AAP36058.1| arginyl-tRNA synthetase [Homo sapiens] 100 0 sp|P54136|SYRC_HUMAN Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens GN=RARS PE=1 SV=2 100 0 F5H3T8 F5H3T8_HUMAN Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens GN=RARS PE=4 SV=1 all3717 487 3.00E-137 COG0018 Arginyl-tRNA synthetase J Translation, ribosomal structure and biogenesis ; K01887|1|0.0|1338|hsa:5917|arginyl-tRNA synthetase [EC:6.1.1.19] GO:0006420//arginyl-tRNA aminoacylation GO:0005524//ATP binding;GO:0034618//arginine binding;GO:0005515//protein binding;GO:0004814//arginine-tRNA ligase activity;GO:0000049//tRNA binding GO:0005829//cytosol;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex;GO:0005739//mitochondrion;GO:0005730//nucleolus 191 sp|Q9UMX5|NENF_HUMAN Neudesin OS=Homo sapiens GN=NENF PE=1 SV=1 22191 MVGPAPRRRLRPLAALALVLALAPGLPTARAGQTPRPAERGPPVRLFTEEELARYGGEEEDQPIYLAVKGVVFDVTSGKEFYGRGAPYNALTGKDSTRGVAKMSLDPADLTHDTTGLTAKELEALDEVFTKVYKAKYPIVGYTARRILNEDGSPNLDFKPEDQPHFDIKDEF 91 12.2 - 3 3 2 2 1 1.01 0.721 2 2 2 - - - 0.910333333 0.164043693 sp|Q9UMX5|NENF_HUMAN 100 3.00E-70 gi|7019545|ref|NP_037481.1| neudesin precursor [Homo sapiens] >gi|14250710|gb|AAH08823.1| Neuron derived neurotrophic factor [Homo sapiens] >gi|55771070|dbj|BAD72063.1| neudesin protein [Homo sapiens] >gi|59803479|gb|AAX07829.1| cell growth-inhibiting protein 47 [Homo sapiens] >gi|119613795|gb|EAW93389.1| neuron derived neurotrophic factor [Homo sapiens] 100 4.00E-71 sp|Q9UMX5|NENF_HUMAN Neudesin OS=Homo sapiens GN=NENF PE=1 SV=1 100 2.00E-58 G7MEL8 G7MEL8_MACMU Putative uncharacterized protein (Fragment) OS=Macaca mulatta GN=EGK_01675 PE=4 SV=1 - - - - - - - - GO:0043410//positive regulation of MAPK cascade GO:0046872//metal ion binding;GO:0008083//growth factor activity;GO:0020037//heme binding GO:0005615//extracellular space 192 tr|B3KM80|B3KM80_HUMAN Nucleolin, isoform CRA_c OS=Homo sapiens GN=NCL PE=2 SV=1 76829 MKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKKTKFE 226 16.2 3 16 16 8 8 1.212 1.288 2.322 7 7 7 - - * 1.607333333 0.62008494 tr|B3KM80|B3KM80_HUMAN 100 0 gi|402889645|ref|XP_003908119.1| PREDICTED: nucleolin isoform 2 [Papio anubis] 100 0 sp|Q5RF26|NUCL_PONAB Nucleolin OS=Pongo abelii GN=NCL PE=2 SV=3 100 0 G8F388 G8F388_MACFA Putative uncharacterized protein (Fragment) OS=Macaca fascicularis GN=EGM_19839 PE=4 SV=1 SPAC140.02 67 9.00E-11 COG0724 RNA-binding proteins (RRM domain) R General function prediction only ; K11294|1|0.0|706|mcc:720965|nucleolin GO:0001525//angiogenesis GO:0003723//RNA binding;GO:0042162//telomeric DNA binding;GO:0008022//protein C-terminus binding;GO:0000166//nucleotide binding GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005938//cell cortex;GO:0030529//ribonucleoprotein complex 193 sp|P63104|1433Z_HUMAN 14-3-3 protein zeta/delta OS=Homo sapiens GN=YWHAZ PE=1 SV=1 >tr|D0PNI1|D0PNI1_HUMAN Epididymis luminal protein 4 OS=Homo sapiens GN=YWHAZ PE=2 SV=1 34287 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN 959 33.1 - 52 34 8 6 0.979 0.766 0.723 24 24 24 - * * 0.822666667 0.137085132 sp|P63104|1433Z_HUMAN 100 2.00E-133 gi|338728575|ref|XP_003365700.1| PREDICTED: 14-3-3 protein zeta/delta-like isoform 3 [Equus caballus] 100 2.00E-134 sp|Q5R651|1433Z_PONAB 14-3-3 protein zeta/delta OS=Pongo abelii GN=YWHAZ PE=2 SV=1 100 6.00E-133 F6XEB4 F6XEB4_HORSE Uncharacterized protein OS=Equus caballus GN=LOC100056060 PE=3 SV=1 SPAC8E11.02c 328 4.00E-90 COG5040 14-3-3 family protein T Signal transduction mechanisms ; K06630|1|3e-136|484|aml:100484483|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein GO:0030168//platelet activation;GO:0010467//gene expression;GO:0007165//signal transduction;GO:0042493//response to drug;GO:0002553//histamine secretion by mast cell;GO:0016071//mRNA metabolic process;GO:0006626//protein targeting to mitochondrion GO:0016301//kinase activity;GO:0019904//protein domain specific binding;GO:0032403//protein complex binding;GO:0008134//transcription factor binding GO:0005654//nucleoplasm;GO:0042470//melanosome;GO:0005829//cytosol;GO:0031252//cell leading edge;GO:0043234//protein complex;GO:0014069//postsynaptic density;GO:0048471//perinuclear region of cytoplasm;GO:0005739//mitochondrion 194 sp|O75326|SEM7A_HUMAN Semaphorin-7A OS=Homo sapiens GN=SEMA7A PE=1 SV=1 84073 MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHLRSGPRIFAVWKGHVGQDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRTVNIGSTKGSCLDKRDCENYITLLERRSEGLLACGTNARHPSCWNLVNGTVVPLGEMRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKVFRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSERSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHACALAASLWLGVLPTLTLGLLVH 153 5.6 - 11 11 3 3 0.696 0.701 0.714 6 5 5 - * * 0.703666667 0.009291573 sp|O75326|SEM7A_HUMAN 100 0 gi|3551779|gb|AAC34741.1| semaphorin L [Homo sapiens] 100 0 sp|O75326|SEM7A_HUMAN Semaphorin-7A OS=Homo sapiens GN=SEMA7A PE=1 SV=1 100 0 F5GYX3 F5GYX3_HUMAN Semaphorin-7A OS=Homo sapiens GN=SEMA7A PE=4 SV=1 - - - - - - - K06529|1|0.0|1274|pon:100451776|semaphorin 7 GO:0007411//axon guidance;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0060907//positive regulation of macrophage cytokine production;GO:0007229//integrin-mediated signaling pathway;GO:0045773//positive regulation of axon extension;GO:0050727//regulation of inflammatory response GO:0005178//integrin binding;GO:0004872//receptor activity GO:0031225//anchored to membrane;GO:0009897//external side of plasma membrane 195 tr|A0A024R2W4|A0A024R2W4_HUMAN Dystroglycan 1 (Dystrophin-associated glycoprotein 1), isoform CRA_a OS=Homo sapiens GN=DAG1 PE=4 SV=1 112424 MRMSVGLSLLLPLWGRTFLLLLSVVMAQSHWPSEPSEAVRDWENQLEASMHSVLSDLHEAVPTVVGIPDGTAVVGRSFRVTIPTDLIASSGDIIKVSAAGKEALPSWLHWDSQSHTLEGLPLDTDKGVHYISVSATRLGANGSHIPQTSSVFSIEVYPEDHSELQSVRTASPDPGEVVSSACAADEPVTVLTVILDADLTKMTPKQRIDLLHRMRSFSEVELHNMKLVPVVNNRLFDMSAFMAGPGNAKKVVENGALLSWKLGCSLNQNSVPDIHGVEAPAREGAMSAQLGYPVVGWHIANKKPPLPKRVRRQIHATPTPVTAIGPPTTAIQEPPSRIVPTPTSPAIAPPTETMAPPVRDPVPGKPTVTIRTRGAIIQTPTLGPIQPTRVSEAGTTVPGQIRPTMTIPGYVEPTAVATPPTTTTKKPRVSTPKPATPSTDSTTTTTRRPTKKPRTPRPVPRVTTKVSITRLETASPPTRIRTTTSGVPRGGEPNQRPELKNHIDRVDAWVGTYFEVKIPSDTFYDHEDTTTDKLKLTLKLREQQLVGEKSWVQFNSNSQLMYGLPDSSHVGKHEYFMHATDKGGLSAVDAFEIHVHRRPQGDRAPARFKAKFVGDPALVLNDIHKKIALVKKLAFAFGDRNCSTITLQNITRGSIVVEWTNNTLPLEPCPKEQIAGLSRRIAEDDGKPRPAFSNALEPDFKATSITVTGSGSCRHLQFIPVVPPRRVPSEAPPTEVPDRDPEKSSEDDVYLHTVIPAVVVAAILLIAGIIAMICYRKKRKGKLTLEDQATFIKKGVPIIFADELDDSKPPPSSSMPLILQEEKAPLPPPEYPNQSVPETTPLNQDTMGEYTPLRDEDPNAPPYQPPPPFTAPMEGKGSRPKNMTPYRSPPPYVPP 286 7.4 1 11 11 4 4 1.007 0.83 1.121 7 7 7 - * - 0.986 0.146632193 tr|A0A024R2W4|A0A024R2W4_HUMAN 100 1.00E-06 gi|1017860|gb|AAB34687.1| cranin=beta-dystroglycan isoform [Ovis aries=sheep, brain, Peptide Partial, 24 aa, segment 1 of 2] 99.89 0 sp|Q14118|DAG1_HUMAN Dystroglycan OS=Homo sapiens GN=DAG1 PE=1 SV=2 100 2.00E-54 E9PE70 E9PE70_HUMAN Alpha-dystroglycan OS=Homo sapiens GN=DAG1 PE=4 SV=1 - - - - - - - K06265|1|0.0|1508|hsa:1605|dystroglycan 1 GO:0030336//negative regulation of cell migration;GO:0060445//branching involved in salivary gland morphogenesis;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0022011//myelination in peripheral nervous system;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0002011//morphogenesis of an epithelial sheet;GO:0016340//calcium-dependent cell-matrix adhesion;GO:0006509//membrane protein ectodomain proteolysis;GO:0006607//NLS-bearing substrate import into nucleus;GO:0043434//response to peptide hormone stimulus;GO:0043409//negative regulation of MAPK cascade;GO:0019048//virus-host interaction;GO:0021682//nerve maturation;GO:0051898//negative regulation of protein kinase B signaling cascade;GO:0034453//microtubule anchoring GO:0051635//bacterial cell surface binding;GO:0043237//laminin-1 binding;GO:0051393//alpha-actinin binding;GO:0005509//calcium ion binding;GO:0042169//SH2 domain binding;GO:0003779//actin binding;GO:0008307//structural constituent of muscle;GO:0015631//tubulin binding;GO:0017166//vinculin binding GO:0005925//focal adhesion;GO:0045121//membrane raft;GO:0005654//nucleoplasm;GO:0030027//lamellipodium;GO:0005604//basement membrane;GO:0016011//dystroglycan complex;GO:0005913//cell-cell adherens junction;GO:0030175//filopodium;GO:0043034//costamere;GO:0005615//extracellular space;GO:0016021//integral to membrane;GO:0033268//node of Ranvier;GO:0042383//sarcolemma;GO:0009279//cell outer membrane;GO:0005856//cytoskeleton;GO:0070938//contractile ring 196 tr|B3KM68|B3KM68_HUMAN cDNA FLJ10398 fis, clone NT2RM4000349, highly similar to Homo sapiens basic leucine zipper and W2 domains 2 (BZW2), mRNA OS=Homo sapiens PE=2 SV=1 61469 MNKHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAVAKFLDSTGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIRRYKYLEKAFEDEMKKLLLFLKAFSETEQTKLAMLSGILLGNGTLPATILTSLFTDSLVKEGIAASFAVKLFKAWMAEKDANSVTSSLRRANLDKRLLELFPVNRQSVDHFAKYFTDAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLWTCIMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEESESEGEEN 36 3.1 6 3 3 2 2 0.848 1.054 1.004 3 3 3 - - - 0.968666667 0.107449213 tr|B3KM68|B3KM68_HUMAN 100 9.00E-74 gi|431908965|gb|ELK12556.1| Basic leucine zipper and W2 domain-containing protein 2 [Pteropus alecto] 99.75 0 sp|Q4R6R4|BZW2_MACFA Basic leucine zipper and W2 domain-containing protein 2 OS=Macaca fascicularis GN=BZW2 PE=2 SV=1 100 8.00E-75 F8WDX8 F8WDX8_HUMAN Basic leucine zipper and W2 domain-containing protein 2 OS=Homo sapiens GN=BZW2 PE=4 SV=1 - - - - - - - K03240|1|6e-07|55.8|xtr:100487780|translation initiation factor eIF-2B subunit epsilon GO:0016070//RNA metabolic process;GO:0030154//cell differentiation;GO:0007399//nervous system development - - 197 sp|P17050|NAGAB_HUMAN Alpha-N-acetylgalactosaminidase OS=Homo sapiens GN=NAGA PE=1 SV=2 >tr|A0A024R1Q5|A0A024R1Q5_HUMAN N-acetylgalactosaminidase, alpha-, isoform CRA_a OS=Homo sapiens GN=NAGA PE=3 SV=1 51306 MLLKTVLLLGHVAQVLMLDNGLLQTPPMGWLAWERFRCNINCDEDPKNCISEQLFMEMADRMAQDGWRDMGYTYLNIDDCWIGGRDASGRLMPDPKRFPHGIPFLADYVHSLGLKLGIYADMGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCFSTPEERAQGYPKMAAALNATGRPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDIQDSWWSVLSILNWFVEHQDILQPVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTDLRTISAQNMDILQNPLMIKINQDPLGIQGRRIHKEKSLIEVYMRPLSNKASALVFFSCRTDMPYRYHSSLGQLNFTGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGVVMWYLYPIKNLEMSQQ 90 8 - 5 5 3 3 1.161 1.008 1.225 3 3 3 - - - 1.131333333 0.111500374 sp|P17050|NAGAB_HUMAN 100 0 gi|4557781|ref|NP_000253.1| alpha-N-acetylgalactosaminidase precursor [Homo sapiens] >gi|127801|sp|P17050.2|NAGAB_HUMAN RecName: Full=Alpha-N-acetylgalactosaminidase; AltName: Full=Alpha-galactosidase B; Flags: Precursor >gi|178248|gb|AAA51677.1| alpha-N-acetylgalactosaminidase [Homo sapiens] >gi|189055|gb|AAA36351.1| alpha-N-acetylgalactosaminidase [Homo sapiens] >gi|1513067|gb|AAB06718.1| alpha-N-acetylgalactosaminidase [Homo sapiens] >gi|12652693|gb|AAH00095.1| N-acetylgalactosaminidase, alpha- [Homo sapiens] >gi|47678585|emb|CAG30413.1| NAGA [Homo sapiens] >gi|119580888|gb|EAW60484.1| N-acetylgalactosaminidase, alpha-, isoform CRA_a [Homo sapiens] >gi|119580889|gb|EAW60485.1| N-acetylgalactosaminidase, alpha-, isoform CRA_a [Homo sapiens] >gi|119580890|gb|EAW60486.1| N-acetylgalactosaminidase, alpha-, isoform CRA_a [Homo sapiens] 100 0 sp|P17050|NAGAB_HUMAN Alpha-N-acetylgalactosaminidase OS=Homo sapiens GN=NAGA PE=1 SV=2 99.51 0 H2QLT5 H2QLT5_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000198951 PE=4 SV=1 - - - - - - - K01204|1|0.0|854|hsa:4668|alpha-N-acetylgalactosaminidase [EC:3.2.1.49] GO:0016052//carbohydrate catabolic process;GO:0046477//glycosylceramide catabolic process;GO:0009311//oligosaccharide metabolic process;GO:0016139//glycoside catabolic process GO:0043169//cation binding;GO:0008456//alpha-N-acetylgalactosaminidase activity;GO:0004557//alpha-galactosidase activity;GO:0042803//protein homodimerization activity GO:0005764//lysosome 198 sp|Q9BRK5|CAB45_HUMAN 45 kDa calcium-binding protein OS=Homo sapiens GN=SDF4 PE=1 SV=1 >tr|A0A024R084|A0A024R084_HUMAN Stromal cell derived factor 4, isoform CRA_c OS=Homo sapiens GN=SDF4 PE=4 SV=1 48891 MVWPWVAMASRWGPLIGLAPCCLWLLGAVLLMDASARPANHSSTRERVANREENEILPPDHLNGVKLEMDGHLNRGFHQEVFLGKDLGGFDEDAEPRRSRRKLMVIFSKVDVNTDRKISAKEMQRWIMEKTAEHFQEAMEESKTHFRAVDPDGDGHVSWDEYKVKFLASKGHSEKEVADAIRLNEELKVDEETQEVLENLKDRWYQADSPPADLLLTEEEFLSFLHPEHSRGMLRFMVKEIVRDLDQDGDKQLSVPEFISLPVGTVENQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTAEELESYMDPMNEYNALNEAKQMIAVADENQNHHLEPEEVLKYSEFFTGSKLVDYARSVHEEF 240 14.9 - 17 17 5 5 1.093 0.907 1.545 7 7 7 - - * 1.181666667 0.32811177 sp|Q9BRK5|CAB45_HUMAN 100 0 gi|18699732|ref|NP_057260.2| 45 kDa calcium-binding protein isoform 2 precursor [Homo sapiens] >gi|21263447|sp|Q9BRK5.1|CAB45_HUMAN RecName: Full=45 kDa calcium-binding protein; Short=Cab45; AltName: Full=Stromal cell-derived factor 4; Short=SDF-4; Flags: Precursor >gi|17467092|gb|AAL40084.1|L79912_1 EF-hand calcium-binding protein of 45 kDa [Homo sapiens] >gi|13623227|gb|AAH06211.1| Stromal cell derived factor 4 [Homo sapiens] >gi|14043268|gb|AAH07625.1| Stromal cell derived factor 4 [Homo sapiens] >gi|14286242|gb|AAH08917.1| Stromal cell derived factor 4 [Homo sapiens] >gi|15030008|gb|AAH11244.1| Stromal cell derived factor 4 [Homo sapiens] >gi|18490407|gb|AAH22375.1| Stromal cell derived factor 4 [Homo sapiens] >gi|119576677|gb|EAW56273.1| stromal cell derived factor 4, isoform CRA_c [Homo sapiens] >gi|119576678|gb|EAW56274.1| stromal cell derived factor 4, isoform CRA_c [Homo sapiens] >gi|119576681|gb|EAW56277.1| stromal cell derived factor 4, isoform CRA_c [Homo sapiens] 100 0 sp|Q9BRK5|CAB45_HUMAN 45 kDa calcium-binding protein OS=Homo sapiens GN=SDF4 PE=1 SV=1 100 2.00E-39 G1QGL3 G1QGL3_NOMLE Uncharacterized protein (Fragment) OS=Nomascus leucogenys GN=SDF4 PE=4 SV=1 - - - - - - - - GO:0045471//response to ethanol;GO:0009650//UV protection;GO:0021549//cerebellum development;GO:0070625//zymogen granule exocytosis;GO:0045444//fat cell differentiation GO:0005509//calcium ion binding;GO:0042802//identical protein binding GO:0005796//Golgi lumen;GO:0032059//bleb;GO:0005770//late endosome;GO:0005886//plasma membrane 199 sp|P04004|VTNC_HUMAN Vitronectin OS=Homo sapiens GN=VTN PE=1 SV=1 >tr|D9ZGG2|D9ZGG2_HUMAN Vitronectin OS=Homo sapiens GN=VTN PE=4 SV=1 61458 MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEEEAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDYRMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL 1774 24.9 - 88 88 10 10 0.747 1.971 0.897 51 29 20 * - - 1.205 0.667601678 sp|P04004|VTNC_HUMAN 100 3.00E-15 gi|170785171|pdb|3BT1|B Chain B, Structure Of Urokinase Receptor, Urokinase And Vitronectin Complex >gi|170785174|pdb|3BT2|B Chain B, Structure Of Urokinase Receptor, Urokinase And Vitronectin Complex 100 0 sp|P04004|VTNC_HUMAN Vitronectin OS=Homo sapiens GN=VTN PE=1 SV=1 100 3.00E-51 F5GX75 F5GX75_HUMAN Vitronectin V65 subunit (Fragment) OS=Homo sapiens GN=VTN PE=4 SV=2 - - - - - - - K06251|1|0.0|939|hsa:7448|vitronectin GO:0032092//positive regulation of protein binding;GO:0090303//positive regulation of wound healing;GO:0033627//cell adhesion mediated by integrin;GO:0010951//negative regulation of endopeptidase activity;GO:0006955//immune response;GO:0061302//smooth muscle cell-matrix adhesion;GO:0030195//negative regulation of blood coagulation;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0014911//positive regulation of smooth muscle cell migration GO:0005178//integrin binding;GO:0005044//scavenger receptor activity;GO:0008201//heparin binding GO:0005615//extracellular space;GO:0071062//alphav-beta3 integrin-vitronectin complex;GO:0031012//extracellular matrix 200 sp|Q9Y490|TLN1_HUMAN Talin-1 OS=Homo sapiens GN=TLN1 PE=1 SV=3 321351 MVALSLKISIGNVVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKKGIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELMEEKKEEITGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQKGERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEHGSVALPAIMRSGASGPENFQVGSMPPAQQQITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFDTLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLEDEGGSGRPLLQAAKGLAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQIGESDTDPHFQDALMQLAKAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGESDLENSRKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASTPKASAGPQPLLVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASAMQLSQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSVVQNLEKDLQEVKAAARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLRSLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVAKAVTQALNRCVSCLPGQRDVDNALRAVGDASKRLLSDSLPPSTGTFQEAQSRLNEAAAGLNQAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLLAAKALSTDPAAPNLKSQLAAAARAVTDSINQLITMCTQQAPGQKECDNALRELETVRELLENPVQPINDMSYFGCLDSVMENSKVLGEAMTGISQNAKNGNLPEFGDAISTASKALCGFTEAAAQAAYLVGVSDPNSQAGQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQVLSAATIVAKHTSALCNSCRLASARTTNPTAKRQFVQSAKEVANSTANLVKTIKALDGAFTEENRAQCRAATAPLLEAVDNLSAFASNPEFSSIPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPSWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLANAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGEPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASEAKPAAVAAENEEIGSHIKHRVQELGHGCAALVTKAGALQCSPSDAYTKKELIECARRVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMFATAGTLNREGTETFADHREGILKTAKVLVEDTKVLVQNAAGSQEKLAQAAQSSVATITRLADVVKLGAASLGAEDPETQVVLINAVKDVAKALGDLISATKAAAGKVGDDPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATTEHIRQELAVFCSPEPPAKTSTPEDFIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRRAIADMLRACKEAAYHPEVAPDVRLRALHYGRECANGYLELLDHVLLTLQKPSPELKQQLTGHSKRVAGSVTELIQAAEAMKGTEWVDPEDPTVIAENELLGAAAAIEAAAKKLEQLKPRAKPKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANALDDGQWSQGLISAARMVAAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVKAAQKAAAFEEQENETVVVKEKMVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQQQYKFLPSELRDEH 926 13.6 - 54 54 26 26 0.845 0.749 0.802 36 36 36 * * * 0.798666667 0.048086727 sp|Q9Y490|TLN1_HUMAN 100 0 gi|223029410|ref|NP_006280.3| talin-1 [Homo sapiens] >gi|81175200|sp|Q9Y490.3|TLN1_HUMAN RecName: Full=Talin-1 >gi|119578756|gb|EAW58352.1| talin 1, isoform CRA_a [Homo sapiens] 100 0 sp|Q9Y490|TLN1_HUMAN Talin-1 OS=Homo sapiens GN=TLN1 PE=1 SV=3 99.86 0 G3QWY0 G3QWY0_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=TLN1 PE=4 SV=1 - - - - - - - K06271|1|0.0|4656|hsa:7094|talin GO:0007411//axon guidance;GO:0030168//platelet activation;GO:0007155//cell adhesion;GO:0007043//cell-cell junction assembly;GO:0006928//cellular component movement;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0006936//muscle contraction;GO:0007044//cell-substrate junction assembly;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0002576//platelet degranulation;GO:0030866//cortical actin cytoskeleton organization GO:0030274//LIM domain binding;GO:0003779//actin binding;GO:0017166//vinculin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005158//insulin receptor binding GO:0005925//focal adhesion;GO:0005911//cell-cell junction;GO:0032587//ruffle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005813//centrosome 201 sp|P54802|ANAG_HUMAN Alpha-N-acetylglucosaminidase OS=Homo sapiens GN=NAGLU PE=1 SV=2 86624 MEAVAVAAAVGVLLLAGAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAAKPGLDTYSLGGGGAARVRVRGSTGVAAAAGLHRYLRDFCGCHVAWSGSQLRLPRPLPAVPGELTEATPNRYRYYQNVCTQSYSFVWWDWARWEREIDWMALNGINLALAWSGQEAIWQRVYLALGLTQAEINEFFTGPAFLAWGRMGNLHTWDGPLPPSWHIKQLYLQHRVLDQMRSFGMTPVLPAFAGHVPEAVTRVFPQVNVTKMGSWGHFNCSYSCSFLLAPEDPIFPIIGSLFLRELIKEFGTDHIYGADTFNEMQPPSSEPSYLAAATTAVYEAMTAVDTEAVWLLQGWLFQHQPQFWGPAQIRAVLGAVPRGRLLVLDLFAESQPVYTRTASFQGQPFIWCMLHNFGGNHGLFGALEAVNGGPEAARLFPNSTMVGTGMAPEGISQNEVVYSLMAELGWRKDPVPDLAAWVTSFAARRYGVSHPDAGAAWRLLLRSVYNCSGEACRGHNRSPLVRRPSLQMNTSIWYNRSDVFEAWRLLLTSAPSLATSPAFRYDLLDLTRQAVQELVSLYYEEARSAYLSKELASLLRAGGVLAYELLPALDEVLASDSRFLLGSWLEQARAAAVSEAEADFYEQNSRYQLTLWGPEGNILDYANKQLAGLVANYYTPRWRLFLEALVDSVAQGIPFQQHQFDKNVFQLEQAFVLSKQRYPSQPRGDTVDLAKKIFLKYYPRWVAGSW 728 17 - 29 29 8 8 1.213 1.142 1.413 23 23 24 * - * 1.256 0.140524019 sp|P54802|ANAG_HUMAN 100 0 gi|66346698|ref|NP_000254.2| alpha-N-acetylglucosaminidase precursor [Homo sapiens] >gi|317373322|sp|P54802.2|ANAG_HUMAN RecName: Full=Alpha-N-acetylglucosaminidase; AltName: Full=N-acetyl-alpha-glucosaminidase; Short=NAG; Contains: RecName: Full=Alpha-N-acetylglucosaminidase 82 kDa form; Contains: RecName: Full=Alpha-N-acetylglucosaminidase 77 kDa form; Flags: Precursor 100 0 sp|P54802|ANAG_HUMAN Alpha-N-acetylglucosaminidase OS=Homo sapiens GN=NAGLU PE=1 SV=2 99.86 0 H2QD21 H2QD21_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000108784 PE=4 SV=1 - - - - - - - K01205|1|0.0|1335|hsa:4669|alpha-N-acetylglucosaminidase [EC:3.2.1.50] GO:0005975//carbohydrate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0044281//small molecule metabolic process;GO:0007399//nervous system development GO:0004561//alpha-N-acetylglucosaminidase activity GO:0043202//lysosomal lumen 202 tr|B4DFW1|B4DFW1_HUMAN cDNA FLJ52457, highly similar to Protein NOV homolog OS=Homo sapiens PE=2 SV=1 46847 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDSLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM 172 7.9 1 7 7 2 2 0.723 0.693 0.654 3 5 5 * - * 0.69 0.034597688 tr|B4DFW1|B4DFW1_HUMAN 100 6.00E-172 gi|194376852|dbj|BAG57572.1| unnamed protein product [Homo sapiens] 95.52 1.00E-169 sp|P48745|NOV_HUMAN Protein NOV homolog OS=Homo sapiens GN=NOV PE=1 SV=1 100 2.00E-171 B4DFW1 B4DFW1_HUMAN cDNA FLJ52457, highly similar to Protein NOV homolog OS=Homo sapiens PE=2 SV=1 - - - - - - - K06827|1|4e-86|318|acs:100562863|connective tissue growth factor GO:0007411//axon guidance;GO:0010468//regulation of gene expression;GO:0001558//regulation of cell growth;GO:0060666//dichotomous subdivision of terminal units involved in salivary gland branching GO:0017154//semaphorin receptor activity;GO:0005520//insulin-like growth factor binding;GO:0008083//growth factor activity GO:0043231//intracellular membrane-bounded organelle;GO:0030424//axon;GO:0002116//semaphorin receptor complex;GO:0016021//integral to membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0031012//extracellular matrix;GO:0005576//extracellular region;GO:0005886//plasma membrane 203 sp|P14174|MIF_HUMAN Macrophage migration inhibitory factor OS=Homo sapiens GN=MIF PE=1 SV=4 >tr|I4AY87|I4AY87_HUMAN Macrophage migration inhibitory factor (Fragment) OS=Homo sapiens PE=2 SV=1 13856 MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 207 7.8 - 34 34 1 1 0.844 0.681 0.601 21 21 20 - * * 0.708666667 0.12383995 sp|P14174|MIF_HUMAN 100 6.00E-63 gi|240104633|pdb|3HOF|A Chain A, Structure Of Macrophage Migration Inhibitory Factor (Mif) With Caffeic Acid At 1.9a Resolution >gi|240104634|pdb|3HOF|B Chain B, Structure Of Macrophage Migration Inhibitory Factor (Mif) With Caffeic Acid At 1.9a Resolution >gi|240104635|pdb|3HOF|C Chain C, Structure Of Macrophage Migration Inhibitory Factor (Mif) With Caffeic Acid At 1.9a Resolution 100 1.00E-63 sp|Q4R549|MIF_MACFA Macrophage migration inhibitory factor OS=Macaca fascicularis GN=MIF PE=3 SV=3 100 3.00E-31 H2QLD1 H2QLD1_PANTR Uncharacterized protein OS=Pan troglodytes GN=MIF PE=4 SV=1 - - - - - - - K07253|1|9e-64|241|mcc:574298|phenylpyruvate tautomerase [EC:5.3.2.1] GO:0006954//inflammatory response;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0048146//positive regulation of fibroblast proliferation;GO:0007506//gonadal mesoderm development;GO:0007530//sex determination;GO:0050918//positive chemotaxis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0001546//preantral ovarian follicle growth;GO:0043030//regulation of macrophage activation;GO:0014070//response to organic cyclic compound;GO:0071157//negative regulation of cell cycle arrest;GO:0090344//negative regulation of cell aging;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0030890//positive regulation of B cell proliferation;GO:0045087//innate immune response;GO:0001516//prostaglandin biosynthetic process;GO:0010629//negative regulation of gene expression;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0050715//positive regulation of cytokine secretion;GO:0030154//cell differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0010739//positive regulation of protein kinase A signaling cascade;GO:0010628//positive regulation of gene expression;GO:0042493//response to drug;GO:0043066//negative regulation of apoptotic process;GO:0001655//urogenital system development;GO:0001880//Mullerian duct regression;GO:0070207//protein homotrimerization GO:0008083//growth factor activity;GO:0005160//transforming growth factor beta receptor binding;GO:0005125//cytokine activity;GO:0004167//dopachrome isomerase activity;GO:0043498//cell surface binding;GO:0050178//phenylpyruvate tautomerase activity;GO:0005179//hormone activity;GO:0042056//chemoattractant activity GO:0009986//cell surface;GO:0005615//extracellular space;GO:0005737//cytoplasm 204 tr|B4DZ36|B4DZ36_HUMAN cDNA FLJ58441, highly similar to Attractin OS=Homo sapiens PE=2 SV=1 150262 MCSRGAVSAPGRWWLQRRQLRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAQCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAAGPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQVQTEQ 48 2.2 1 3 3 2 2 --- 1.125 --- 1 2 1 - - - 1.125 - tr|B4DZ36|B4DZ36_HUMAN 100 0 gi|194380362|dbj|BAG63948.1| unnamed protein product [Homo sapiens] 99.56 0 sp|O75882|ATRN_HUMAN Attractin OS=Homo sapiens GN=ATRN PE=1 SV=2 100 0 B4DZ36 B4DZ36_HUMAN cDNA FLJ58441, highly similar to Attractin OS=Homo sapiens PE=2 SV=1 - - - - - - - K09434|1|4e-13|78.2|ssc:100516083|ETS domain-containing transcription factor ERF!K06243|4|3e-11|72.0|bta:530599|laminin, beta 2!K09608|5|3e-10|68.9|mgp:100551456|tolloid-like protein 1 [EC:3.4.24.-] GO:0006954//inflammatory response;GO:0040014//regulation of multicellular organism growth;GO:0006979//response to oxidative stress GO:0004872//receptor activity;GO:0030246//carbohydrate binding GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0005887//integral to plasma membrane 205 tr|E9PNW4|E9PNW4_HUMAN CD59 glycoprotein OS=Homo sapiens GN=CD59 PE=1 SV=1 14733 MGIQGGSVLFGLLLVLAVFCHSGHSLQCYNCPNPTADCKTAVNCSSDFDACLITKAGLQVYNKCWKFEHCNFNDVTTRLRENELTYYCCKKDLCNFNEQLENGSEPGA 88 20.4 2 6 6 2 2 0.628 0.738 0.463 6 6 6 * - * 0.609666667 0.138413631 tr|E9PNW4|E9PNW4_HUMAN 100 4.00E-38 gi|157830573|pdb|1CDQ|A Chain A, Structure Of A Soluble, Glycosylated Form Of The Human Complement Regulatory Protein Cd59 >gi|157830574|pdb|1CDR|A Chain A, Structure Of A Soluble, Glycosylated Form Of The Human Complement Regulatory Protein Cd59 >gi|157830575|pdb|1CDS|A Chain A, Structure Of A Soluble, Glycosylated Form Of The Human Complement Regulatory Protein Cd59 100 5.00E-47 sp|P13987|CD59_HUMAN CD59 glycoprotein OS=Homo sapiens GN=CD59 PE=1 SV=1 100 6.00E-48 E9PNW4 E9PNW4_HUMAN CD59 glycoprotein OS=Homo sapiens GN=CD59 PE=4 SV=1 - - - - - - - K04008|1|5e-47|186|hsa:966|CD59 antigen GO:0007166//cell surface receptor signaling pathway;GO:0007596//blood coagulation GO:0005515//protein binding GO:0005576//extracellular region;GO:0031362//anchored to external side of plasma membrane 206 sp|P04792|HSPB1_HUMAN Heat shock protein beta-1 OS=Homo sapiens GN=HSPB1 PE=1 SV=2 >tr|V9HW43|V9HW43_HUMAN Epididymis secretory protein Li 102 OS=Homo sapiens GN=HEL-S-102 PE=2 SV=1 25259 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEITIPVTFESRAQLGGPEAAKSDETAAK 193 28.8 - 16 16 5 5 1.001 0.909 0.241 5 5 4 - - - 0.717 0.414786692 sp|P04792|HSPB1_HUMAN 100 3.00E-35 gi|241307|gb|AAB20722.1| estrogen receptor-related protein [Homo sapiens] 100 3.00E-107 sp|P04792|HSPB1_HUMAN Heat shock protein beta-1 OS=Homo sapiens GN=HSPB1 PE=1 SV=2 100 6.00E-106 G3QJQ8 G3QJQ8_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=HSPB1 PE=3 SV=1 - - - - - - - K04455|1|3e-107|387|mcc:715615|heat shock 27kDa protein 1 GO:0001525//angiogenesis;GO:0009615//response to virus;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0043534//blood vessel endothelial cell migration;GO:0032731//positive regulation of interleukin-1 beta production;GO:0006446//regulation of translational initiation;GO:0035767//endothelial cell chemotaxis;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0016071//mRNA metabolic process;GO:0006986//response to unfolded protein;GO:0043122//regulation of I-kappaB kinase/NF-kappaB cascade GO:0005080//protein kinase C binding;GO:0043130//ubiquitin binding;GO:0008426//protein kinase C inhibitor activity GO:0005829//cytosol;GO:0009986//cell surface;GO:0005819//spindle;GO:0000502//proteasome complex;GO:0030018//Z disc;GO:0005886//plasma membrane;GO:0005634//nucleus 207 sp|P28074|PSB5_HUMAN Proteasome subunit beta type-5 OS=Homo sapiens GN=PSMB5 PE=1 SV=3 31371 MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP 90 15.6 - 4 4 3 3 0.396 0.975 0.695 4 4 4 * - * 0.688666667 0.289551953 sp|P28074|PSB5_HUMAN 100 8.00E-131 gi|31874085|emb|CAD97956.1| hypothetical protein [Homo sapiens] 100 9.00E-132 sp|Q5R8S2|PSB5_PONAB Proteasome subunit beta type-5 OS=Pongo abelii GN=PSMB5 PE=2 SV=3 100 3.00E-88 E9PAV2 E9PAV2_HUMAN Proteasome subunit beta type-5 OS=Homo sapiens GN=PSMB5 PE=3 SV=1 SPAC4A8.13c 270 2.00E-72 COG0638 20S proteasome, alpha and beta subunits O Posttranslational modification, protein turnover, chaperones ; K02737|1|9e-132|469|pon:100173015|20S proteasome subunit beta 5 [EC:3.4.25.1] GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0019048//virus-host interaction;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006979//response to oxidative stress;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0005515//protein binding;GO:0004298//threonine-type endopeptidase activity GO:0005654//nucleoplasm;GO:0005839//proteasome core complex;GO:0005829//cytosol 208 sp|Q6UVK1|CSPG4_HUMAN Chondroitin sulfate proteoglycan 4 OS=Homo sapiens GN=CSPG4 PE=1 SV=2 260193 MQSGPRPPLPAPGLALALTLTMLARLASAASFFGENHLEVPVATALTDIDLQLQFSTSQPEALLLLAAGPADHLLLQLYSGRLQVRLVLGQEELRLQTPAETLLSDSIPHTVVLTVVEGWATLSVDGFLNASSAVPGAPLEVPYGLFVGGTGTLGLPYLRGTSRPLRGCLHAATLNGRSLLRPLTPDVHEGCAEEFSASDDVALGFSGPHSLAAFPAWGTQDEGTLEFTLTTQSRQAPLAFQAGGRRGDFIYVDIFEGHLRAVVEKGQGTVLLHNSVPVADGQPHEVSVHINAHRLEISVDQYPTHTSNRGVLSYLEPRGSLLLGGLDAEASRHLQEHRLGLTPEATNASLLGCMEDLSVNGQRRGLREALLTRNMAAGCRLEEEEYEDDAYGHYEAFSTLAPEAWPAMELPEPCVPEPGLPPVFANFTQLLTISPLVVAEGGTAWLEWRHVQPTLDLMEAELRKSQVLFSVTRGARHGELELDIPGAQARKMFTLLDVVNRKARFIHDGSEDTSDQLVLEVSVTARVPMPSCLRRGQTYLLPIQVNPVNDPPHIIFPHGSLMVILEHTQKPLGPEVFQAYDPDSACEGLTFQVLGTSSGLPVERRDQPGEPATEFSCRELEAGSLVYVHRGGPAQDLTFRVSDGLQASPPATLKVVAIRPAIQIHRSTGLRLAQGSAMPILPANLSVETNAVGQDVSVLFRVTGALQFGELQKQGAGGVEGAEWWATQAFHQRDVEQGRVRYLSTDPQHHAYDTVENLALEVQVGQEILSNLSFPVTIQRATVWMLRLEPLHTQNTQQETLTTAHLEATLEEAGPSPPTFHYEVVQAPRKGNLQLQGTRLSDGQGFTQDDIQAGRVTYGATARASEAVEDTFRFRVTAPPYFSPLYTFPIHIGGDPDAPVLTNVLLVVPEGGEGVLSADHLFVKSLNSASYLYEVMERPRHGRLAWRGTQDKTTMVTSFTNEDLLRGRLVYQHDDSETTEDDIPFVATRQGESSGDMAWEEVRGVFRVAIQPVNDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADSGFADAQLVLTRKDLLFGSIVAVDEPTRPIYRFTQEDLRKRRVLFVHSGADRGWIQLQVSDGQHQATALLEVQASEPYLRVANGSSLVVPQGGQGTIDTAVLHLDTNLDIRSGDEVHYHVTAGPRWGQLVRAGQPATAFSQQDLLDGAVLYSHNGSLSPRDTMAFSVEAGPVHTDATLQVTIALEGPLAPLKLVRHKKIYVFQGEAAEIRRDQLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRGALADEPPSLDPVQSFSQEAVDTGRVLYLHSRPEAWSDAFSLDVASGLGAPLEGVLVELEVLPAAIPLEAQNFSVPEGGSLTLAPPLLRVSGPYFPTLLGLSLQVLEPPQHGALQKEDGPQARTLSAFSWRMVEEQLIRYVHDGSETLTDSFVLMANASEMDRQSHPVAFTVTVLPVNDQPPILTTNTGLQMWEGATAPIPAEALRSTDGDSGSEDLVYTIEQPSNGRVVLRGAPGTEVRSFTQAQLDGGLVLFSHRGTLDGGFRFRLSDGEHTSPGHFFRVTAQKQVLLSLKGSQTLTVCPGSVQPLSSQTLRASSSAGTDPQLLLYRVVRGPQLGRLFHAQQDSTGEALVNFTQAEVYAGNILYEHEMPPEPFWEAHDTLELQLSSPPARDVAATLAVAVSFEAACPQRPSHLWKNKGLWVPEGQRARITVAALDASNLLASVPSPQRSEHDVLFQVTQFPSRGQLLVSEEPLHAGQPHFLQSQLAAGQLVYAHGGGGTQQDGFHFRAHLQGPAGASVAGPQTSEAFAITVRDVNERPPQPQASVPLRLTRGSRAPISRAQLSVVDPDSAPGEIEYEVQRAPHNGFLSLVGGGLGPVTRFTQADVDSGRLAFVANGSSVAGIFQLSMSDGASPPLPMSLAVDILPSAIEVQLRAPLEVPQALGRSSLSQQQLRVVSDREEPEAAYRLIQGPQYGHLLVGGRPTSAFSQFQIDQGEVVFAFTNFSSSHDHFRVLALARGVNASAVVNVTVRALLHVWAGGPWPQGATLRLDPTVLDAGELANRTGSVPRFRLLEGPRHGRVVRVPRARTEPGGSQLVEQFTQQDLEDGRLGLEVGRPEGRAPGPAGDSLTLELWAQGVPPAVASLDFATEPYNAARPYSVALLSVPEAARTEAGKPESSTPTGEPGPMASSPEPAVAKGGFLSFLEANMFSVIIPMCLVLLLLALILPLLFYLRKRNKTGKHDVQVLTAKPRNGLAGDTETFRKVEPGQAIPLTAVPGQGPPPGGQPDPELLQFCRTPNPALKNGQYWV 654 9.8 - 35 35 16 16 0.763 0.614 0.715 18 17 16 * * * 0.697333333 0.076054805 sp|Q6UVK1|CSPG4_HUMAN 100 0 gi|34148711|gb|AAQ62842.1| melanoma chondroitin sulfate proteoglycan [Homo sapiens] 100 0 sp|Q6UVK1|CSPG4_HUMAN Chondroitin sulfate proteoglycan 4 OS=Homo sapiens GN=CSPG4 PE=1 SV=2 100 7.00E-150 A2VCL1 A2VCL1_HUMAN CSPG4 protein (Fragment) OS=Homo sapiens GN=CSPG4 PE=2 SV=1 - - - - - - - K08115|1|0.0|4180|hsa:1464|chondroitin sulfate proteoglycan 4 GO:0001525//angiogenesis;GO:0030207//chondroitin sulfate catabolic process;GO:0048771//tissue remodeling;GO:0008283//cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008347//glial cell migration;GO:0048663//neuron fate commitment;GO:0005975//carbohydrate metabolic process;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0044281//small molecule metabolic process;GO:0016322//neuron remodeling;GO:0000187//activation of MAPK activity;GO:0035556//intracellular signal transduction;GO:0030208//dermatan sulfate biosynthetic process GO:0004871//signal transducer activity;GO:0019901//protein kinase binding;GO:0005518//collagen binding GO:0005576//extracellular region;GO:0009986//cell surface;GO:0005796//Golgi lumen;GO:0031258//lamellipodium membrane;GO:0043202//lysosomal lumen;GO:0005887//integral to plasma membrane;GO:0016324//apical plasma membrane 209 tr|B7Z7P8|B7Z7P8_HUMAN Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens GN=ETF1 PE=1 SV=1 58378 MKQDVLNCTEGPIHSNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDDY 77 11.8 1 7 7 4 4 1.42 0.919 0.946 3 3 3 - - - 1.095 0.281781831 tr|B7Z7P8|B7Z7P8_HUMAN 100 0 gi|15679932|gb|AAH14269.1| ETF1 protein [Homo sapiens] >gi|30583587|gb|AAP36038.1| eukaryotic translation termination factor 1 [Homo sapiens] >gi|119582536|gb|EAW62132.1| eukaryotic translation termination factor 1, isoform CRA_b [Homo sapiens] >gi|149017199|gb|EDL76250.1| eukaryotic translation termination factor 1 [Rattus norvegicus] >gi|465952157|gb|EMP24759.1| Eukaryotic peptide chain release factor subunit 1 [Chelonia mydas] 100 0 sp|P62495|ERF1_HUMAN Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens GN=ETF1 PE=1 SV=3 100 0 E1BTM1 E1BTM1_CHICK Uncharacterized protein OS=Gallus gallus GN=ETF1 PE=4 SV=1 YBR143c 584 8.00E-167 COG1503 Peptide chain release factor 1 (eRF1) J Translation, ribosomal structure and biogenesis ; K03265|1|0.0|842|tgu:100220649|peptide chain release factor subunit 1 GO:0006355//regulation of transcription, DNA-dependent;GO:0006479//protein methylation;GO:0006449//regulation of translational termination;GO:0019048//virus-host interaction;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0016149//translation release factor activity, codon specific;GO:0043022//ribosome binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity GO:0005829//cytosol;GO:0005634//nucleus 210 sp|O14498|ISLR_HUMAN Immunoglobulin superfamily containing leucine-rich repeat protein OS=Homo sapiens GN=ISLR PE=1 SV=1 49333 MQELHLLWWALLLGLAQACPEPCDCGEKYGFQIADCAYRDLESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINENPFDCTCGIVWLKTWALTTAVSIPEQDNIACTSPHVLKGTPLSRLPPLPCSAPSVQLSYQPSQDGAELRPGFVLALHCDVDGQPAPQLHWHIQIPSGIVEITSPNVGTDGRALPGTPVASSQPRFQAFANGSLLIPDFGKLEEGTYSCLATNELGSAESSVDVALATPGEGGEDTLGRRFHGKAVEGKGCYTVDNEVQPSGPEDNVVIIYLSRAGNPEAAVAEGVPGQLPPGLLLLGQSLLLFFFLTSF 887 20.8 - 34 34 6 6 1.564 1.816 1.908 29 27 28 * - - 1.762666667 0.178093608 sp|O14498|ISLR_HUMAN 100 0 gi|5031809|ref|NP_005536.1| immunoglobulin superfamily containing leucine-rich repeat protein precursor [Homo sapiens] >gi|41582239|ref|NP_958934.1| immunoglobulin superfamily containing leucine-rich repeat protein precursor [Homo sapiens] >gi|74762091|sp|O14498.1|ISLR_HUMAN RecName: Full=Immunoglobulin superfamily containing leucine-rich repeat protein; Flags: Precursor >gi|2554604|dbj|BAA22848.1| ISLR [Homo sapiens] >gi|6172371|dbj|BAA85970.1| ISLR [Homo sapiens] >gi|6172373|dbj|BAA85971.1| ISLR [Homo sapiens] >gi|18490897|gb|AAH22478.1| Immunoglobulin superfamily containing leucine-rich repeat [Homo sapiens] >gi|37182860|gb|AAQ89230.1| ISLR [Homo sapiens] >gi|83405860|gb|AAI11014.1| Immunoglobulin superfamily containing leucine-rich repeat [Homo sapiens] >gi|119619763|gb|EAW99357.1| immunoglobulin superfamily containing leucine-rich repeat, isoform CRA_a [Homo sapiens] >gi|119619764|gb|EAW99358.1| immunoglobulin superfamily containing leucine-rich repeat, isoform CRA_a [Homo sapiens] 100 0 sp|O14498|ISLR_HUMAN Immunoglobulin superfamily containing leucine-rich repeat protein OS=Homo sapiens GN=ISLR PE=1 SV=1 100 2.00E-79 H0YL90 H0YL90_HUMAN Immunoglobulin superfamily-containing leucine-rich repeat protein (Fragment) OS=Homo sapiens GN=ISLR PE=4 SV=1 SPy1798 54.7 3.00E-07 COG4886 Leucine-rich repeat (LRR) protein S Function unknown ; K06839|1|1e-22|108|cin:100184475|slit 2!K06850|5|1e-19|98.6|cfa:489132|slit 3 GO:0007155//cell adhesion - GO:0005576//extracellular region 211 sp|P35442|TSP2_HUMAN Thrombospondin-2 OS=Homo sapiens GN=THBS2 PE=1 SV=2 147474 MVWRLVLLALWVWPSTQAGHQDKDTTFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRFDYIPPVNADDLSKITKIMRQKEGFFLTAQLKQDGKSRGTLLALEGPGLSQRQFEIVSNGPADTLDLTYWIDGTRHVVSLEDVGLADSQWKNVTVQVAGETYSLHVGCDLIDSFALDEPFYEHLQAEKSRMYVAKGSARESHFRGLLQNVHLVFENSVEDILSKKGCQQGQGAEINAISENTETLRLGPHVTTEYVGPSSERRPEVCERSCEELGNMVQELSGLHVLVNQLSENLKRVSNDNQFLWELIGGPPKTRNMSACWQDGRFFAENETWVVDSCTTCTCKKFKTICHQITCPPATCASPSFVEGECCPSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCDVTSNTCLGPSIQTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNCKGSGRETKACQGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRSCPVDGCLSNPCFPGAQCSSFPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCVNTQPGFHCLPCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCKDKTHNCHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQLLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNANQADHDRDGQGDACDPDDDNDGVPDDRDNCRLVFNPDQEDLDGDGRGDICKDDFDNDNIPDIDDVCPENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI 649 13.7 - 36 24 12 9 0.908 0.912 0.78 16 16 16 - - * 0.866666667 0.075082177 sp|P35442|TSP2_HUMAN 100 0 gi|119567838|gb|EAW47453.1| thrombospondin 2, isoform CRA_a [Homo sapiens] 100 0 sp|P35442|TSP2_HUMAN Thrombospondin-2 OS=Homo sapiens GN=THBS2 PE=1 SV=2 100 0 Q6MZL6 Q6MZL6_HUMAN Putative uncharacterized protein DKFZp686G02190 (Fragment) OS=Homo sapiens GN=DKFZp686G02190 PE=2 SV=1 - - - - - - - K04659|1|0.0|2188|hsa:7058|thrombospondin GO:0016525//negative regulation of angiogenesis;GO:0007155//cell adhesion;GO:0051965//positive regulation of synapse assembly GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding GO:0005604//basement membrane 212 sp|Q15485|FCN2_HUMAN Ficolin-2 OS=Homo sapiens GN=FCN2 PE=1 SV=2 39607 MELDRAVGVLGAATLLLSFLGMAWALQAADTCPEVKMVGLEGSDKLTILRGCPGLPGAPGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRPA 51 10.5 - 3 3 3 3 --- 1.109 1.121 1 2 2 - - - 1.115 0.008485281 sp|Q15485|FCN2_HUMAN 100 5.00E-157 gi|61744445|ref|NP_004099.2| ficolin-2 isoform a precursor [Homo sapiens] >gi|166214934|sp|Q15485.2|FCN2_HUMAN RecName: Full=Ficolin-2; AltName: Full=37 kDa elastin-binding protein; AltName: Full=Collagen/fibrinogen domain-containing protein 2; AltName: Full=EBP-37; AltName: Full=Ficolin-B; AltName: Full=Ficolin-beta; AltName: Full=Hucolin; AltName: Full=L-ficolin; AltName: Full=Serum lectin p35; Flags: Precursor >gi|47479679|gb|AAH69825.1| Ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) [Homo sapiens] >gi|47481200|gb|AAH69572.1| Ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) [Homo sapiens] >gi|77702084|gb|ABB01005.1| ficolin-2 [Homo sapiens] >gi|119608539|gb|EAW88133.1| ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin), isoform CRA_a [Homo sapiens] 100 6.00E-158 sp|Q15485|FCN2_HUMAN Ficolin-2 OS=Homo sapiens GN=FCN2 PE=1 SV=2 97.44 2.00E-153 H2QY50 H2QY50_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000160339 PE=4 SV=1 - - - - - - - K10104|1|7e-158|556|hsa:2220|ficolin GO:0008228//opsonization;GO:0007165//signal transduction;GO:0001867//complement activation, lectin pathway GO:0003823//antigen binding;GO:0030246//carbohydrate binding;GO:0005509//calcium ion binding;GO:0005102//receptor binding;GO:0048306//calcium-dependent protein binding GO:0005615//extracellular space;GO:0005581//collagen 213 sp|P00558|PGK1_HUMAN Phosphoglycerate kinase 1 OS=Homo sapiens GN=PGK1 PE=1 SV=3 >tr|V9HWF4|V9HWF4_HUMAN Phosphoglycerate kinase OS=Homo sapiens GN=HEL-S-68p PE=2 SV=1 58066 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI 1498 37.4 - 76 76 12 12 0.673 0.633 0.574 51 53 53 - - * 0.626666667 0.049802945 sp|P00558|PGK1_HUMAN 100 0 gi|193506632|pdb|2ZGV|A Chain A, Crystal Structure Of Human Phosphoglycerate Kinase Bound To D-Adp >gi|193506672|pdb|3C39|A Chain A, Crystal Structure Of Human Phosphoglycerate Kinase Bound To 3-Phosphoglycerate >gi|193506673|pdb|3C39|B Chain B, Crystal Structure Of Human Phosphoglycerate Kinase Bound To 3-Phosphoglycerate >gi|193506674|pdb|3C3A|A Chain A, Crystal Structure Of Human Phosphoglycerate Kinase Bound To 3-Phosphoglycerate And L-Adp >gi|193506675|pdb|3C3A|B Chain B, Crystal Structure Of Human Phosphoglycerate Kinase Bound To 3-Phosphoglycerate And L-Adp >gi|193506676|pdb|3C3B|A Chain A, Crystal Structure Of Human Phosphoglycerate Kinase Bound To D-Cdp >gi|193506677|pdb|3C3B|B Chain B, Crystal Structure Of Human Phosphoglycerate Kinase Bound To D-Cdp >gi|193506678|pdb|3C3C|A Chain A, Crystal Structure Of Human Phosphoglycerate Kinase Bound To 3-Phosphoglycerate And L-Cdp >gi|193506679|pdb|3C3C|B Chain B, Crystal Structure Of Human Phosphoglycerate Kinase Bound To 3-Phosphoglycerate And L-Cdp 100 0 sp|A5A6K4|PGK1_PANTR Phosphoglycerate kinase 1 OS=Pan troglodytes GN=PGK1 PE=2 SV=1 100 0 B7Z7A9 B7Z7A9_HUMAN Phosphoglycerate kinase OS=Homo sapiens GN=PGK1 PE=2 SV=1 SPBC14F5.04c 564 9.00E-161 COG0126 3-phosphoglycerate kinase G Carbohydrate transport and metabolism ; K00927|1|0.0|846|ptr:473678|phosphoglycerate kinase [EC:2.7.2.3] GO:0006094//gluconeogenesis;GO:0016310//phosphorylation;GO:0044281//small molecule metabolic process;GO:0006096//glycolysis GO:0043531//ADP binding;GO:0004618//phosphoglycerate kinase activity;GO:0005524//ATP binding GO:0005829//cytosol 214 tr|B2RA94|B2RA94_HUMAN cDNA, FLJ94779 OS=Homo sapiens PE=2 SV=1 51485 MFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEEEEEETR 420 18.4 1 21 21 6 6 1.756 1.201 1.691 16 16 16 * - - 1.549333333 0.303411162 tr|B2RA94|B2RA94_HUMAN 100 0 gi|37181708|gb|AAQ88661.1| EGEE293 [Homo sapiens] 99.74 0 sp|Q7Z5L7|PODN_HUMAN Podocan OS=Homo sapiens GN=PODN PE=1 SV=2 100 0 B2RA94 B2RA94_HUMAN cDNA, FLJ94779 OS=Homo sapiens PE=2 SV=1 alr0124_1 87.4 4.00E-17 COG4886 Leucine-rich repeat (LRR) protein S Function unknown ; K08764|1|0.0|698|ptr:456862|sterol carrier protein 2 [EC:2.3.1.176] GO:0008285//negative regulation of cell proliferation;GO:0030336//negative regulation of cell migration GO:0005518//collagen binding GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 215 sp|Q13219|PAPP1_HUMAN Pappalysin-1 OS=Homo sapiens GN=PAPPA PE=1 SV=3 204506 MRLWSWVLHLGLLSAALGCGLAERPRRARRDPRAGRPPRPAAGPATCATRAARGRRASPPPPPPPGGAWEAVRVPRRRQQREARGATEEPSPPSRALYFSGRGEQLRLRADLELPRDAFTLQVWLRAEGGQRSPAVITGLYDKCSYISRDRGWVVGIHTISDQDNKDPRYFFSLKTDRARQVTTINAHRSYLPGQWVYLAATYDGQFMKLYVNGAQVATSGEQVGGIFSPLTQKCKVLMLGGSALNHNYRGYIEHFSLWKVARTQREILSDMETHGAHTALPQLLLQENWDNVKHAWSPMKDGSSPKVEFSNAHGFLLDTSLEPPLCGQTLCDNTEVIASYNQLSSFRQPKVVRYRVVNLYEDDHKNPTVTREQVDFQHHQLAEAFKQYNISWELDVLEVSNSSLRRRLILANCDISKIGDENCDPECNHTLTGHDGGDCRHLRHPAFVKKQHNGVCDMDCNYERFNFDGGECCDPEITNVTQTCFDPDSPHRAYLDVNELKNILKLDGSTHLNIFFAKSSEEELAGVATWPWDKEALMHLGGIVLNPSFYGMPGHTHTMIHEIGHSLGLYHVFRGISEIQSCSDPCMETEPSFETGDLCNDTNPAPKHKSCGDPGPGNDTCGFHSFFNTPYNNFMSYADDDCTDSFTPNQVARMHCYLDLVYQGWQPSRKPAPVALAPQVLGHTTDSVTLEWFPPIDGHFFERELGSACHLCLEGRILVQYASNASSPMPCSPSGHWSPREAEGHPDVEQPCKSSVRTWSPNSAVNPHTVPPACPEPQGCYLELEFLYPLVPESLTIWVTFVSTDWDSSGAVNDIKLLAVSGKNISLGPQNVFCDVPLTIRLWDVGEEVYGIQIYTLDEHLEIDAAMLTSTADTPLCLQCKPLKYKVVRDPPLQMDVASILHLNRKFVDMDLNLGSVYQYWVITISGTEESEPSPAVTYIHGSGYCGDGIIQKDQGEQCDDMNKINGDGCSLFCRQEVSFNCIDEPSRCYFHDGDGVCEEFEQKTSIKDCGVYTPQGFLDQWASNASVSHQDQQCPGWVIIGQPAASQVCRTKVIDLSEGISQHAWYPCTISYPYSQLAQTTFWLRAYFSQPMVAAAVIVHLVTDGTYYGDQKQETISVQLLDTKDQSHDLGLHVLSCRNNPLIIPVVHDLSQPFYHSQAVRVSFSSPLVAISGVALRSFDNFDPVTLSSCQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTVRDIPHWLNPTRVERVVCTAGLKWYPHPALIHCVKGCEPFMGDNYCDAINNRAFCNYDGGDCCTSTVKTKKVTPFPMSCDLQGDCACRDPQAQEHSRKDLRGYSHG 403 7.9 - 20 20 10 10 0.805 0.567 0.63 15 15 15 * - * 0.667333333 0.123313962 sp|Q13219|PAPP1_HUMAN 100 3.00E-42 gi|194390314|dbj|BAG61919.1| unnamed protein product [Homo sapiens] 100 0 sp|Q13219|PAPP1_HUMAN Pappalysin-1 OS=Homo sapiens GN=PAPPA PE=1 SV=3 100 9.00E-42 E7EMD3 E7EMD3_HUMAN Pappalysin-1 OS=Homo sapiens GN=PAPPA PE=4 SV=2 - - - - - - - K07762|1|0.0|3204|hsa:5069|pappalysin-1 [EC:3.4.24.79] GO:0030154//cell differentiation;GO:0051384//response to glucocorticoid stimulus;GO:0007565//female pregnancy;GO:0006508//proteolysis GO:0004175//endopeptidase activity;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity GO:0005615//extracellular space;GO:0016020//membrane 216 tr|Q53F10|Q53F10_HUMAN UV excision repair protein RAD23 homolog B variant (Fragment) OS=Homo sapiens PE=2 SV=1 49532 MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTALKEYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSSTTTTVAQAPTPVPALAPTSTPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPTATDSTSGDSSRSNLFEDATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRGVEYLLMGIPGDRESQAVVDPPQAASTGVPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQPQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMNYIQVTPQEKEAIGRLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED 179 11.7 1 11 11 4 4 0.642 0.519 0.648 6 6 6 * - * 0.603 0.072807967 tr|Q53F10|Q53F10_HUMAN 100 2.00E-38 gi|387849175|ref|NP_001248717.1| UV excision repair protein RAD23 homolog B [Macaca mulatta] 100 2.00E-39 sp|P54727|RD23B_HUMAN UV excision repair protein RAD23 homolog B OS=Homo sapiens GN=RAD23B PE=1 SV=1 100 7.00E-39 Q5W0S5 Q5W0S5_HUMAN RAD23 homolog B (S. cerevisiae) (Fragment) OS=Homo sapiens GN=RAD23B PE=2 SV=1 SPBC2D10.12 222 1.00E-57 COG5272 Ubiquitin O Posttranslational modification, protein turnover, chaperones ; K10839|1|2e-101|369|mcc:711328|UV excision repair protein RAD23 GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0000715//nucleotide-excision repair, DNA damage recognition GO:0031593//polyubiquitin binding;GO:0003697//single-stranded DNA binding GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0071942//XPC complex 217 tr|B7Z4B2|B7Z4B2_HUMAN cDNA FLJ56108, highly similar to Puromycin-sensitive aminopeptidase (EC 3.4.11.-) OS=Homo sapiens PE=2 SV=1 110166 MNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTTPSGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLENASGKPIAAVMNTWTKQMGFPLIYVEAEQVEDDRLLRLSQKKFCAGGSYVGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMNVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFANEPNYTVWSDLSCNLGILSTLLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFKDHVEGKQILSADLRSPVYLTVLKHGDGTTLDIMFKLHKQADMQEEKNRIERVLGATLLPDLIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELYNRYQGGFLISRLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQCCENILLNAAWLKRDAESIHQYLLQRKASPPTV 236 15.4 3 16 16 11 11 0.695 0.849 0.671 10 10 10 * - * 0.738333333 0.096588474 tr|B7Z4B2|B7Z4B2_HUMAN 100 0 gi|221041642|dbj|BAH12498.1| unnamed protein product [Homo sapiens] 99.76 0 sp|P55786|PSA_HUMAN Puromycin-sensitive aminopeptidase OS=Homo sapiens GN=NPEPPS PE=1 SV=2 100 0 B7Z4B2 B7Z4B2_HUMAN cDNA FLJ56108, highly similar to Puromycin-sensitive aminopeptidase (EC 3.4.11.-) OS=Homo sapiens PE=2 SV=1 SPBC1921.05 514 3.00E-145 COG0308 Aminopeptidase N E Amino acid transport and metabolism ; K08776|1|0.0|1657|hsa:9520|puromycin-sensitive aminopeptidase [EC:3.4.11.-] GO:0071456//cellular response to hypoxia;GO:0000209//protein polyubiquitination;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0006508//proteolysis GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity GO:0005634//nucleus;GO:0005829//cytosol 218 tr|V9HWK1|V9HWK1_HUMAN Triosephosphate isomerase OS=Homo sapiens GN=HEL-S-49 PE=2 SV=1 33326 MAPSRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ 1843 58.2 1 66 66 10 10 0.829 0.649 0.675 50 51 50 * - - 0.717666667 0.097289945 tr|V9HWK1|V9HWK1_HUMAN 100 6.00E-92 gi|384475517|ref|NP_001244955.1| triosephosphate isomerase isoform 3 [Homo sapiens] 100 2.00E-144 sp|P60174|TPIS_HUMAN Triosephosphate isomerase OS=Homo sapiens GN=TPI1 PE=1 SV=3 100 1.00E-118 G3QJI7 G3QJI7_GORGO Triosephosphate isomerase (Fragment) OS=Gorilla gorilla gorilla GN=TPI1 PE=3 SV=1 YDR050c 274 1.00E-73 COG0149 Triosephosphate isomerase G Carbohydrate transport and metabolism ; K01803|1|2e-144|511|ptr:451799|triosephosphate isomerase (TIM) [EC:5.3.1.1] GO:0006098//pentose-phosphate shunt;GO:0019682//glyceraldehyde-3-phosphate metabolic process;GO:0006096//glycolysis;GO:0006094//gluconeogenesis;GO:0009790//embryo development GO:0004807//triose-phosphate isomerase activity GO:0005829//cytosol;GO:0005634//nucleus 219 tr|A0A024RBK9|A0A024RBK9_HUMAN Thioredoxin reductase 1 OS=Homo sapiens GN=TXNRD1 PE=3 SV=1 82829 MAAVVLAKDHHPGKTLPENPAGFTSTATADSRALLQAYIDGHSVVIFSRSTCTRCTEVKKLFKSLCVPYFVLELDQTEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGC 238 16.9 8 13 13 7 7 0.97 0.868 0.578 7 7 7 - - * 0.805333333 0.203374859 tr|A0A024RBK9|A0A024RBK9_HUMAN 100 0 gi|221040568|dbj|BAH11961.1| unnamed protein product [Homo sapiens] 100 0 sp|Q16881|TRXR1_HUMAN Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens GN=TXNRD1 PE=1 SV=3 100 0 F5H780 F5H780_HUMAN Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens GN=TXNRD1 PE=3 SV=1 CC2302 280 6.00E-75 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes C Energy production and conversion ; K00384|1|0.0|1223|hsa:7296|thioredoxin reductase (NADPH) [EC:1.8.1.9] GO:0042744//hydrogen peroxide catabolic process;GO:0022900//electron transport chain;GO:0045454//cell redox homeostasis;GO:0007165//signal transduction;GO:0044255//cellular lipid metabolic process;GO:0008283//cell proliferation;GO:0001707//mesoderm formation;GO:0015949//nucleobase-containing small molecule interconversion GO:0009055//electron carrier activity;GO:0050660//flavin adenine dinucleotide binding;GO:0050661//NADP binding;GO:0004791//thioredoxin-disulfide reductase activity;GO:0015035//protein disulfide oxidoreductase activity GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005730//nucleolus 220 sp|P02647|APOA1_HUMAN Apolipoprotein A-I OS=Homo sapiens GN=APOA1 PE=1 SV=1 >tr|A0A024R3E3|A0A024R3E3_HUMAN Apolipoprotein A-I, isoform CRA_a OS=Homo sapiens GN=APOA1 PE=4 SV=1 37756 MKAAVLTLAVLFLTGSQARHFWQQDEPPQSPWDRVKDLATVYVDVLKDSGRDYVSQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLNTQ 4762 61 - 247 247 17 17 0.799 2.33 0.985 178 103 106 * - - 1.371333333 0.835422249 sp|P02647|APOA1_HUMAN 100 5.00E-100 gi|2914175|pdb|1AV1|A Chain A, Crystal Structure Of Human Apolipoprotein A-I >gi|2914176|pdb|1AV1|B Chain B, Crystal Structure Of Human Apolipoprotein A-I >gi|2914177|pdb|1AV1|C Chain C, Crystal Structure Of Human Apolipoprotein A-I >gi|2914178|pdb|1AV1|D Chain D, Crystal Structure Of Human Apolipoprotein A-I 100 9.00E-135 sp|P02647|APOA1_HUMAN Apolipoprotein A-I OS=Homo sapiens GN=APOA1 PE=1 SV=1 100 3.00E-133 H2Q4U3 H2Q4U3_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000118137 PE=4 SV=1 - - - - - - - K08757|1|1e-134|479|ptr:451564|apolipoprotein A-I GO:0070508//cholesterol import;GO:0050728//negative regulation of inflammatory response;GO:0001935//endothelial cell proliferation;GO:0051347//positive regulation of transferase activity;GO:0033344//cholesterol efflux;GO:0001932//regulation of protein phosphorylation;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0018206//peptidyl-methionine modification;GO:0030300//regulation of intestinal cholesterol absorption;GO:0043691//reverse cholesterol transport;GO:0008211//glucocorticoid metabolic process;GO:0002740//negative regulation of cytokine secretion involved in immune response;GO:0050713//negative regulation of interleukin-1 beta secretion;GO:0030168//platelet activation;GO:0018158//protein oxidation;GO:0006656//phosphatidylcholine biosynthetic process;GO:0034375//high-density lipoprotein particle remodeling;GO:0043534//blood vessel endothelial cell migration;GO:0042632//cholesterol homeostasis;GO:0034384//high-density lipoprotein particle clearance;GO:0019915//lipid storage;GO:0002576//platelet degranulation;GO:0051346//negative regulation of hydrolase activity;GO:0006695//cholesterol biosynthetic process;GO:0010903//negative regulation of very-low-density lipoprotein particle remodeling;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0034380//high-density lipoprotein particle assembly;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042158//lipoprotein biosynthetic process;GO:0050821//protein stabilization;GO:0032488//Cdc42 protein signal transduction;GO:0060354//negative regulation of cell adhesion molecule production;GO:0055091//phospholipid homeostasis;GO:0010873//positive regulation of cholesterol esterification;GO:0070328//triglyceride homeostasis;GO:0030325//adrenal gland development;GO:0033700//phospholipid efflux;GO:0051345//positive regulation of hydrolase activity GO:0005543//phospholipid binding;GO:0001540//beta-amyloid binding;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0015485//cholesterol binding;GO:0034191//apolipoprotein A-I receptor binding;GO:0042802//identical protein binding;GO:0008035//high-density lipoprotein particle binding;GO:0017127//cholesterol transporter activity;GO:0019899//enzyme binding;GO:0070653//high-density lipoprotein particle receptor binding GO:0030139//endocytic vesicle;GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0030141//secretory granule;GO:0034361//very-low-density lipoprotein particle;GO:0034366//spherical high-density lipoprotein particle 221 tr|B3KSI4|B3KSI4_HUMAN Transketolase OS=Homo sapiens PE=2 SV=1 71435 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA 664 23.7 3 32 32 10 10 1.021 0.755 0.929 19 21 19 - - - 0.901666667 0.135090093 tr|B3KSI4|B3KSI4_HUMAN 100 0 gi|31417921|gb|AAH02433.1| TKT protein [Homo sapiens] 96.55 3.00E-26 sp|Q5R1W6|TKT_PANTR Transketolase OS=Pan troglodytes GN=TKT PE=2 SV=1 100 0 B3KPZ8 B3KPZ8_HUMAN cDNA FLJ32530 fis, clone SMINT2000185, highly similar to TRANSKETOLASE (EC 2.2.1.1) OS=Homo sapiens PE=2 SV=1 all4052 460 3.00E-129 COG0021 Transketolase G Carbohydrate transport and metabolism ; K00615|1|0.0|944|hsa:7086|transketolase [EC:2.2.1.1] GO:0048146//positive regulation of fibroblast proliferation;GO:0046390//ribose phosphate biosynthetic process;GO:0045669//positive regulation of osteoblast differentiation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030199//collagen fibril organization;GO:0005999//xylulose biosynthetic process;GO:0010763//positive regulation of fibroblast migration;GO:0090091//positive regulation of extracellular matrix disassembly;GO:0035988//chondrocyte proliferation;GO:0006112//energy reserve metabolic process;GO:0040008//regulation of growth;GO:0003416//endochondral bone growth;GO:0046166//glyceraldehyde-3-phosphate biosynthetic process;GO:0046777//protein autophosphorylation;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0007155//cell adhesion;GO:0030500//regulation of bone mineralization;GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0045860//positive regulation of protein kinase activity GO:0042803//protein homodimerization activity;GO:0048029//monosaccharide binding;GO:0000287//magnesium ion binding;GO:0004802//transketolase activity;GO:0005524//ATP binding;GO:0038062//protein tyrosine kinase collagen receptor activity;GO:0005518//collagen binding;GO:0030976//thiamine pyrophosphate binding GO:0005777//peroxisome;GO:0005829//cytosol;GO:0005887//integral to plasma membrane;GO:0005730//nucleolus;GO:0005789//endoplasmic reticulum membrane 222 tr|B2RBR9|B2RBR9_HUMAN cDNA, FLJ95650, highly similar to Homo sapiens karyopherin (importin) beta 1 (KPNB1), mRNA OS=Homo sapiens PE=2 SV=1 111819 MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSLVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA 67 8.7 1 7 7 6 6 0.712 0.675 0.96 3 3 3 - - - 0.782333333 0.15497204 tr|B2RBR9|B2RBR9_HUMAN 100 2.00E-169 gi|67967733|dbj|BAE00349.1| unnamed protein product [Macaca fascicularis] 99.89 0 sp|Q14974|IMB1_HUMAN Importin subunit beta-1 OS=Homo sapiens GN=KPNB1 PE=1 SV=2 100 0 B2RBR9 B2RBR9_HUMAN cDNA, FLJ95650, highly similar to Homo sapiens karyopherin (importin) beta 1 (KPNB1), mRNA OS=Homo sapiens PE=2 SV=1 SPAC1B1.03c 649 0 COG5215 Karyopherin (importin) beta U Intracellular trafficking, secretion, and vesicular transport ; K14293|1|0.0|1753|hsa:3837|importin subunit beta-1 GO:0006309//apoptotic DNA fragmentation;GO:0000060//protein import into nucleus, translocation;GO:0019221//cytokine-mediated signaling pathway;GO:0006607//NLS-bearing substrate import into nucleus;GO:0019058//viral infectious cycle;GO:0019048//virus-host interaction;GO:0006610//ribosomal protein import into nucleus GO:0008565//protein transporter activity;GO:0008270//zinc ion binding;GO:0008139//nuclear localization sequence binding;GO:0019904//protein domain specific binding GO:0005829//cytosol;GO:0031965//nuclear membrane;GO:0005643//nuclear pore;GO:0005654//nucleoplasm 223 tr|G3V180|G3V180_HUMAN Dipeptidyl peptidase 3 OS=Homo sapiens GN=DPP3 PE=1 SV=1 95009 MGEPEAGSEFANGAAAAAGPMADTQYILPNDIGVSSLDCREAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFWKGPSEAPSGQA 193 6.2 6 8 8 4 4 1.085 0.771 0.773 7 7 6 - * - 0.876333333 0.180713401 tr|G3V180|G3V180_HUMAN 100 0 gi|119594947|gb|EAW74541.1| hCG2016942, isoform CRA_d [Homo sapiens] 100 0 sp|Q9NY33|DPP3_HUMAN Dipeptidyl peptidase 3 OS=Homo sapiens GN=DPP3 PE=1 SV=2 100 0 G3V180 G3V180_HUMAN Dipeptidyl peptidase 3 OS=Homo sapiens GN=DPP3 PE=4 SV=1 - - - - - - - K01277|1|0.0|1507|hsa:10072|dipeptidyl-peptidase III [EC:3.4.14.4] GO:0006508//proteolysis GO:0046872//metal ion binding;GO:0008239//dipeptidyl-peptidase activity;GO:0004177//aminopeptidase activity;GO:0008237//metallopeptidase activity GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane 224 sp|O00151|PDLI1_HUMAN PDZ and LIM domain protein 1 OS=Homo sapiens GN=PDLIM1 PE=1 SV=4 >tr|V9HW92|V9HW92_HUMAN Epididymis secretory protein Li 112 OS=Homo sapiens GN=HEL-S-112 PE=2 SV=1 43502 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQPPSSLVIDKESEVYKMLQEKQELNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYCEKHARERVTPPEGYEVVTVFPK 244 21.6 - 13 13 5 5 0.844 0.671 0.518 9 9 9 - * * 0.677666667 0.163102217 sp|O00151|PDLI1_HUMAN 100 8.00E-159 gi|119570397|gb|EAW50012.1| PDZ and LIM domain 1 (elfin), isoform CRA_d [Homo sapiens] 100 0 sp|O00151|PDLI1_HUMAN PDZ and LIM domain protein 1 OS=Homo sapiens GN=PDLIM1 PE=1 SV=4 100 4.00E-175 H2Q2B3 H2Q2B3_PANTR Uncharacterized protein (Fragment) OS=Pan troglodytes GN=ENSG00000107438 PE=4 SV=1 - - - - - - - K08202|1|7e-16|85.1|oaa:100079308|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5!K09374|2|2e-06|53.9|mdo:100016250|LIM homeobox protein 3/4 GO:0001666//response to hypoxia;GO:0006979//response to oxidative stress;GO:0006355//regulation of transcription, DNA-dependent GO:0008270//zinc ion binding;GO:0003713//transcription coactivator activity GO:0005856//cytoskeleton;GO:0005667//transcription factor complex;GO:0005737//cytoplasm 225 tr|B2RCM5|B2RCM5_HUMAN cDNA, FLJ96160, highly similar to Homo sapiens EGF-containing fibulin-like extracellular matrix protein 2 (EFEMP2), mRNA OS=Homo sapiens PE=2 SV=1 52942 MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCANFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF 162 10.8 5 11 11 4 4 1.552 2.286 1.594 7 8 9 * * * 1.810666667 0.412186042 tr|B2RCM5|B2RCM5_HUMAN 100 1.00E-21 gi|62087822|dbj|BAD92358.1| mutant p53 binding protein 1 variant [Homo sapiens] 99.55 0 sp|O95967|FBLN4_HUMAN EGF-containing fibulin-like extracellular matrix protein 2 OS=Homo sapiens GN=EFEMP2 PE=1 SV=3 100 0 B2RCM5 B2RCM5_HUMAN cDNA, FLJ96160, highly similar to Homo sapiens EGF-containing fibulin-like extracellular matrix protein 2 (EFEMP2), mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K08023|1|6e-37|155|mdo:100030163|latent transforming growth factor beta binding protein GO:0007596//blood coagulation GO:0004888//transmembrane signaling receptor activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005509//calcium ion binding GO:0016020//membrane;GO:0005604//basement membrane 226 sp|P26022|PTX3_HUMAN Pentraxin-related protein PTX3 OS=Homo sapiens GN=PTX3 PE=1 SV=3 45257 MHLLAILFCALWSAVLAENSDDYDLMYVNLDNEIDNGLHPTEDPTPCACGQEHSEWDKLFIMLENSQMRERMLLQATDDVLRGELQRLREELGRLAESLARPCAPGAPAEARLTSALDELLQATRDAGRRLARMEGAEAQRPEEAGRALAAVLEELRQTRADLHAVQGWAARSWLPAGCETAILFPMRSKKIFGSVHPVRPMRLESFSACIWVKATDVLNKTILFSYGTKRNPYEIQLYLSYQSIVFVVGGEENKLVAEAMVSLGRWTHLCGTWNSEEGLTSLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYVS 917 26.2 - 57 57 7 7 0.564 0.688 0.496 42 44 38 * - - 0.582666667 0.097351596 sp|P26022|PTX3_HUMAN 100 0 gi|167900484|ref|NP_002843.2| pentraxin-related protein PTX3 precursor [Homo sapiens] >gi|296452984|sp|P26022.3|PTX3_HUMAN RecName: Full=Pentraxin-related protein PTX3; AltName: Full=Pentaxin-related protein PTX3; AltName: Full=Tumor necrosis factor alpha-induced protein 5; Short=TNF alpha-induced protein 5; AltName: Full=Tumor necrosis factor-inducible gene 14 protein; Short=TSG-14; Flags: Precursor >gi|77176698|gb|ABA64467.1| pentaxin-related protein PTX3 [Homo sapiens] >gi|119599114|gb|EAW78708.1| pentraxin-related gene, rapidly induced by IL-1 beta [Homo sapiens] 100 0 sp|P26022|PTX3_HUMAN Pentraxin-related protein PTX3 OS=Homo sapiens GN=PTX3 PE=1 SV=3 98.43 0 G3RH48 G3RH48_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=PTX3 PE=4 SV=1 - - - - - - - K01672|1|7e-23|108|dre:100006448|carbonic anhydrase [EC:4.2.1.1]!K11453|5|3e-17|90.1|mcc:702133|chromobox protein 6 GO:0048666//neuron development;GO:0030901//midbrain development;GO:0007626//locomotory behavior;GO:0001878//response to yeast;GO:0071542//dopaminergic neuron differentiation;GO:0050766//positive regulation of phagocytosis;GO:0070306//lens fiber cell differentiation;GO:0008228//opsonization;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0006954//inflammatory response;GO:0045893//positive regulation of transcription, DNA-dependent;GO:0002089//lens morphogenesis in camera-type eye GO:0005515//protein binding;GO:0001872//(1->3)-beta-D-glucan binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity GO:0005576//extracellular region;GO:0005634//nucleus 227 tr|B4DTT0|B4DTT0_HUMAN cDNA FLJ51090, highly similar to N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) OS=Homo sapiens PE=2 SV=1 61676 MYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNFEPFFMMIATPAPHSPWTAAPQYQKAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPILRGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSALWNLQYCEFDDQEVFVEVYNLTADPDQITNIAKTIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNRGSVRTRRFSKHLL 420 17.1 6 40 40 9 9 1.463 1.09 1.814 18 19 19 * - - 1.455666667 0.362055705 tr|B4DTT0|B4DTT0_HUMAN 100 0 gi|4504061|ref|NP_002067.1| N-acetylglucosamine-6-sulfatase precursor [Homo sapiens] >gi|232126|sp|P15586.3|GNS_HUMAN RecName: Full=N-acetylglucosamine-6-sulfatase; AltName: Full=Glucosamine-6-sulfatase; Short=G6S; Flags: Precursor >gi|31867|emb|CAA78164.1| N-acetylglucosamine-6-sulphatase [Homo sapiens] >gi|15214696|gb|AAH12482.1| Glucosamine (N-acetyl)-6-sulfatase [Homo sapiens] >gi|119617544|gb|EAW97138.1| glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), isoform CRA_a [Homo sapiens] >gi|119617546|gb|EAW97140.1| glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), isoform CRA_a [Homo sapiens] 100 0 sp|P15586|GNS_HUMAN N-acetylglucosamine-6-sulfatase OS=Homo sapiens GN=GNS PE=1 SV=3 100 8.00E-142 F5H4C6 F5H4C6_HUMAN N-acetylglucosamine-6-sulfatase (Fragment) OS=Homo sapiens GN=GNS PE=4 SV=1 mll7612 100 7.00E-21 COG3119 Arylsulfatase A and related enzymes P Inorganic ion transport and metabolism ; K01137|1|0.0|986|hsa:2799|N-acetylglucosamine-6-sulfatase [EC:3.1.6.14] GO:0042340//keratan sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process GO:0046872//metal ion binding;GO:0008449//N-acetylglucosamine-6-sulfatase activity;GO:0005515//protein binding GO:0043202//lysosomal lumen 228 sp|Q8TDY8|IGDC4_HUMAN Immunoglobulin superfamily DCC subclass member 4 OS=Homo sapiens GN=IGDCC4 PE=1 SV=1 146693 MARGDAGRGRGLLALTFCLLAARGELLLPQETTVELSCGVGPLQVILGPEQAAVLNCSLGAAAAGPPTRVTWSKDGDTLLEHDHLHLLPNGSLWLSQPLAPNGSDESVPEAVGVIEGNYSCLAHGPLGVLASQTAVVKLATLADFSLHPESQTVEENGTARFECHIEGLPAPIITWEKDQVTLPEEPRLIVLPNGVLQILDVQESDAGPYRCVATNSARQHFSQEALLSVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPISTDVIVLGRTNLLIANAQPWHSGVYVCRANKPRTRDFATAAAELRVLAAPAITQAPEALSRTRASTARFVCRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVVREGLPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKARGMDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQLSLSSPNPSDIRVAWLPLPPSLSNGQVVKYKIEYGLGKEDQIFSTEVRGNETQLMLNSLQPNKVYRVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVPFAPAELKVQAKMESLVVSWQPPPHPTQISGYKLYWREVGAEEEANGDRLPGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPAPDMPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFSPWGLRNASLVTYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSSNHTQPEHQWTLLTTQGNIFSAEVHGLESDTRYFFKMGARTEVGPGPFSRLQDVITLQEKLSDSLDMHSVTGIIVGVCLGLLCLLACMCAGLRRSPHRESLPGLSSTATPGNPALYSRARLGPPSPPAAHELESLVHPHPQDWSPPPSDVEDRAEVHSLMGGGVSEGRSHSKRKISWAQPSGLSWAGSWAGCELPQAGPRPALTRALLPPAGTGQTLLLQALVYDAIKGNGRKKSPPACRNQVEAEVIVHSDFSASNGNPDLHLQDLEPEDPLPPEAPDLISGVGDPGQGAAWLDRELGGCELAAPGPDRLTCLPEAASASCSYPDLQPGEVLEETPGDSCQLKSPCPLGASPGLPRSPVSSSA 61 2.2 - 2 2 2 2 1.012 1.255 1.863 2 2 2 - - - 1.376666667 0.438351837 sp|Q8TDY8|IGDC4_HUMAN 100 0 gi|119598131|gb|EAW77725.1| likely ortholog of mouse neighbor of Punc E11, isoform CRA_c [Homo sapiens] 100 0 sp|Q8TDY8|IGDC4_HUMAN Immunoglobulin superfamily DCC subclass member 4 OS=Homo sapiens GN=IGDCC4 PE=2 SV=1 100 0 C9JPJ5 C9JPJ5_HUMAN Immunoglobulin superfamily DCC subclass member 4 OS=Homo sapiens GN=IGDCC4 PE=4 SV=1 - - - - - - - K06766|1|3e-58|228|api:100160084|neogenin!K06765|4|8e-53|210|xla:378529|deleted in colorectal carcinoma - - GO:0005887//integral to plasma membrane 229 tr|A0A087WUS3|A0A087WUS3_HUMAN Calsyntenin-2 OS=Homo sapiens GN=CLSTN2 PE=4 SV=1 115349 LASQDSHSLFPSAGEICAFKIHGQELPFEAVVLNKTSGEGRLRAKSPIDCELQKEYTFIIQAYDCGAGPHETAWKKSHKAVVHIQVKDVNEFAPTFKEPAYKAVVTEGKIYDSILQVEAIDEDCSPQYSQICNYEIVTTDVPFAIDRNGNIRNTEKLSYDKQHQYEILVTAYDCGQKPAAQDTLVQVDVKPVCKPGWQDWTKRIEYQPGSGSMPLFPSIHLETCDGAVSSLQIVTELQTNYIGKGCDRETYSEKSLQKLCGASSGIIDLLPSPSAATNWTAGLLVDSSEMIFKFDGRQGAKVPDGIVPKNLTDQFTITMWMKHGPSPGVRAEKETILCNSDKTEMNRHHYALYVHNCRLVFLLRKDFDQADTFRPAEFHWKLDQICDKEWHYYVINVEFPVVTLYMDGATYEPYLVTNDWPIHPSHIAMQLTVGACWQGGEVTKPQFAQFFHGSLASLTIRPGKMESQKVISCLQACKEGLDINSLESLGQGIKYHFNPSQSILVMEGDDIGNINRALQKVSYINSRQFPTAGVRRLKVSSKVQCFGEDVCISIPEVDAYVMVLQAIEPRITLRGTDHFWRPAAQFESARGVTLFPDIKIVSTFAKTEAPGDVKTTDPKSEVLEEMLHNLDFCDILVIGGDLDPRQECLELNHSELHQRHLDATNSTAGYSIYGVGSMSRYEQVLHHIRYRNWRPASLEARRFRIKCSELNGRYTSNEFNLEVSILHEDQVSDKEHVNHLIVQPPFLQSVHHPESRSSIQHSSVVPSIATVVIIISVCMLVFVVAMGVYRVRIAHQHFIQETEAAKESEMDWDDSALTITVNPMEKHEGPGHGEDETEGEEEEEAEEEMSSSSGSDDSEEEEEEEGMGRGRHGQNGARQAQLEWDDSTLPY 143 5.7 1 14 14 5 5 0.884 1.235 1.093 6 5 6 - - - 1.070666667 0.176562548 tr|A0A087WUS3|A0A087WUS3_HUMAN 100 6.00E-107 gi|39644518|gb|AAH04871.2| CLSTN2 protein, partial [Homo sapiens] 98.99 0 sp|Q9H4D0|CSTN2_HUMAN Calsyntenin-2 OS=Homo sapiens GN=CLSTN2 PE=1 SV=2 100 9.00E-30 B3KUA5 B3KUA5_HUMAN cDNA FLJ39499 fis, clone PROST2016777, highly similar to Calsyntenin-2 OS=Homo sapiens PE=4 SV=1 - - - - - - - K04601|1|6e-10|67.0|cin:100185193|cadherin EGF LAG seven-pass G-type receptor 2 (flamingo)!K04600|4|9e-09|63.2|xtr:100038051|cadherin EGF LAG seven-pass G-type receptor 1 (flamingo) GO:0007156//homophilic cell adhesion GO:0005509//calcium ion binding GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane;GO:0045211//postsynaptic membrane;GO:0005886//plasma membrane;GO:0016021//integral to membrane 230 sp|Q15365|PCBP1_HUMAN Poly(rC)-binding protein 1 OS=Homo sapiens GN=PCBP1 PE=1 SV=2 >tr|Q53SS8|Q53SS8_HUMAN Epididymis secretory protein Li 85 OS=Homo sapiens GN=PCBP1 PE=2 SV=1 42550 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIITLTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSEKGMGCS 132 12.1 - 8 8 3 3 1.402 0.913 0.953 4 4 4 - - - 1.089333333 0.271514886 sp|Q15365|PCBP1_HUMAN 100 3.00E-164 gi|90086375|dbj|BAE91740.1| unnamed protein product [Macaca fascicularis] 100 0 sp|Q5E9A3|PCBP1_BOVIN Poly(rC)-binding protein 1 OS=Bos taurus GN=PCBP1 PE=2 SV=1 100 0 H2QI21 H2QI21_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000169564 PE=4 SV=1 - - - - - - - K12889|1|0.0|727|ecb:100050579|poly(rC)-binding protein 1 GO:0000398//mRNA splicing, via spliceosome;GO:0045727//positive regulation of translation GO:0003723//RNA binding;GO:0008494//translation activator activity;GO:0005515//protein binding;GO:0003697//single-stranded DNA binding GO:0030529//ribonucleoprotein complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm 231 tr|A0A024QZV0|A0A024QZV0_HUMAN HCG1811539, isoform CRA_b OS=Homo sapiens GN=hCG_1811539 PE=3 SV=1 44330 MEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFVLSQAKDEL 397 29 4 31 31 8 8 0.847 0.963 0.965 11 12 12 - - - 0.925 0.067557383 tr|A0A024QZV0|A0A024QZV0_HUMAN 100 2.00E-179 gi|42794771|ref|NP_110437.2| thioredoxin domain-containing protein 5 isoform 1 precursor [Homo sapiens] >gi|29839560|sp|Q8NBS9.2|TXND5_HUMAN RecName: Full=Thioredoxin domain-containing protein 5; AltName: Full=Endoplasmic reticulum resident protein 46; Short=ER protein 46; Short=ERp46; AltName: Full=Thioredoxin-like protein p46; Flags: Precursor >gi|37182414|gb|AAQ89009.1| disulfide isomerase [Homo sapiens] >gi|119575624|gb|EAW55220.1| hCG1811539, isoform CRA_a [Homo sapiens] 100 2.00E-180 sp|Q8NBS9|TXND5_HUMAN Thioredoxin domain-containing protein 5 OS=Homo sapiens GN=TXNDC5 PE=1 SV=2 100 2.00E-179 Q86UY0 Q86UY0_HUMAN TXNDC5 protein OS=Homo sapiens GN=TXNDC5 PE=2 SV=1 SPAC17H9.14c 129 7.00E-30 COG0526 Thiol-disulfide isomerase and thioredoxins OC Posttranslational modification, protein turnover, chaperones ; Energy production and conversion ; K13984|1|0.0|633|hsa:81567|thioredoxin domain-containing protein 5 GO:0006662//glycerol ether metabolic process;GO:0006892//post-Golgi vesicle-mediated transport;GO:0045454//cell redox homeostasis;GO:0016044//cellular membrane organization GO:0009055//electron carrier activity;GO:0016853//isomerase activity;GO:0015035//protein disulfide oxidoreductase activity GO:0043202//lysosomal lumen;GO:0005788//endoplasmic reticulum lumen 232 tr|A0A024QZ42|A0A024QZ42_HUMAN HCG1985580, isoform CRA_c OS=Homo sapiens GN=PDCD6 PE=1 SV=1 16323 MFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV 110 10.7 2 2 2 1 1 1.366 0.738 0.952 2 2 2 - - - 1.018666667 0.319263736 tr|A0A024QZ42|A0A024QZ42_HUMAN 100 7.00E-65 gi|198443166|pdb|2ZN9|A Chain A, Crystal Structure Of Ca2+-bound Form Of Des3-20alg-2 >gi|198443167|pdb|2ZN9|B Chain B, Crystal Structure Of Ca2+-bound Form Of Des3-20alg-2 >gi|198443168|pdb|2ZND|A Chain A, Crystal Structure Of Ca2+-Free Form Of Des3-20alg-2 100 3.00E-66 sp|O75340|PDCD6_HUMAN Programmed cell death protein 6 OS=Homo sapiens GN=PDCD6 PE=1 SV=1 100 3.00E-65 G3IFX0 G3IFX0_CRIGR Programmed cell death protein 6 OS=Cricetulus griseus GN=I79_022645 PE=4 SV=1 - - - - - - - K07359|1|4e-44|176|dpo:Dpse_GA27481|calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17]!K13510|2|2e-17|87.4|ptr:454095|lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]!K08585|3|3e-17|87.0|nvi:100119123|calpain, invertebrate [EC:3.4.22.-]!K08583|5|2e-16|84.0|dre:550598|calpain, small subunit 1 GO:0033554//cellular response to stress;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006886//intracellular protein transport;GO:0051592//response to calcium ion GO:0005509//calcium ion binding;GO:0060090//binding, bridging;GO:0048306//calcium-dependent protein binding;GO:0042803//protein homodimerization activity GO:0031965//nuclear membrane;GO:0031410//cytoplasmic vesicle;GO:0005789//endoplasmic reticulum membrane 233 sp|P0CG39|POTEJ_HUMAN POTE ankyrin domain family member J OS=Homo sapiens GN=POTEJ PE=3 SV=1 143685 MVAEVDSMPAASSVKKPFVLRSKMGKWCRHCFPCCRGSGKSNVGTSGDQDDSTMKTLRSKMGKWCCHCFPCCRGSGKSNVGAWGDYDDSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANGNSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKERDFLHENSMLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNLLKALQLNELTMDDDTAVLVIDNGSGMCKAGFAGDDAPRAVFPSIVGCPRQQGMMGGMHQKESYVGKEAQSKRGILTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAMLSLYTSGRTTGIVMDSGDGVTHTVPIYDGNALPHATLRLDLAGRELTDYLMKILTERGYRFTTMAEREIVRDIKEKLCYVALDFEQEMAMVASSSSLEKSYELPDGQVITISNEWFRCPEALFQPCFLGMESCGIHETTFNSIMKSDVDIRKDLYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMMKIRIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 393 4.5 - 18 4 3 1 --- 0.507 0.701 1 2 2 - - - 0.604 0.137178716 sp|P0CG39|POTEJ_HUMAN 100 0 gi|459352730|ref|NP_001264012.1| POTE ankyrin domain family member J [Homo sapiens] >gi|300681052|sp|P0CG39.1|POTEJ_HUMAN RecName: Full=POTE ankyrin domain family member J 100 0 sp|P0CG39|POTEJ_HUMAN POTE ankyrin domain family member J OS=Homo sapiens GN=POTEJ PE=3 SV=1 96.22 0 H2QW46 H2QW46_PANTR Uncharacterized protein (Fragment) OS=Pan troglodytes GN=ENSG00000222038 PE=3 SV=1 SPBC32H8.12c 671 0 COG5277 Actin and related proteins Z Cytoskeleton ; K05692|1|0.0|724|mgp:100303677|actin beta/gamma 1 - GO:0005524//ATP binding GO:0005938//cell cortex 234 tr|Q6MZW0|Q6MZW0_HUMAN Putative uncharacterized protein DKFZp686J11235 (Fragment) OS=Homo sapiens GN=DKFZp686J11235 PE=1 SV=1 60566 TQYPRPSSEAPRAQLLTMDWTWRILFLVAAATGAHSQVQLLQSGAEVKTPGASVKLSCKPSGNTVNIYALHWLRQAPGHGPEWMTWLNVENGNMMSSHYFRPRLTVTRDASANTVYMELTSLTSEDTAVYFCASERGGLFDVWGPGTTVTVSSASPTSPKVFPLSLCSTQPDGNVVIACLVQGFFPQEPLSVTWSESGQGVTARNFPPSQDASGDLYTTSSQLTLPATQCLAGKSVTCHVKHYTNPSQDVTVPCPVPSTPPTPSPSTPPTPSPSCCHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGVTFTWTPSSGKSAVQGPPERDLCGCYSVSSVLPGCAEPWNHGKTFTCTAAYPESKTPLTATLSKSGNTFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASRQEPSQGTTTFAVTSILRVAAEDWKKGDTFSCMVGHEALPLAFTQKTIDRLAGKPTHVNVSVVMAEVDGTCY 73 10.5 8 10 10 5 5 0.727 3.063 --- 5 4 1 - * - 1.895 1.651801441 tr|Q6MZW0|Q6MZW0_HUMAN 100 4.00E-58 gi|169249225|gb|ACA51871.1| immunoglobulin heavy chain constant alpha 1 membrane bound isoform 2 [Homo sapiens] 100 0 sp|P01876|IGHA1_HUMAN Ig alpha-1 chain C region OS=Homo sapiens GN=IGHA1 PE=1 SV=2 100 0 Q6MZW0 Q6MZW0_HUMAN Putative uncharacterized protein DKFZp686J11235 (Fragment) OS=Homo sapiens GN=DKFZp686J11235 PE=1 SV=1 - - - - - - - K06856|1|3e-151|535|bta:524810|immunoglobulin heavy chain GO:0018298//protein-chromophore linkage;GO:0006955//immune response GO:0003823//antigen binding - 235 tr|A0A024R972|A0A024R972_HUMAN Laminin, gamma 1 (Formerly LAMB2), isoform CRA_a OS=Homo sapiens GN=LAMC1 PE=4 SV=1 204490 MDECTDEGGRPQRCMPEFVNAAFNVTVVATNTCGTPPEEYCVQTGVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYFPRYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYVFRLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAGYLDDVTLASARPGPGVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVADHRVKLQELESLIANLGTGDEMVTDQAFEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAKKQEAAIMDYNRDIEEIMKDIRNLEDIRKTLPSGCFNTPSIEKP 1490 15.7 1 67 67 18 18 1.3 1.354 1.326 45 45 44 * * * 1.326666667 0.027006172 tr|A0A024R972|A0A024R972_HUMAN 100 0 gi|145309326|ref|NP_002284.3| laminin subunit gamma-1 precursor [Homo sapiens] >gi|224471885|sp|P11047.3|LAMC1_HUMAN RecName: Full=Laminin subunit gamma-1; AltName: Full=Laminin B2 chain; AltName: Full=Laminin-1 subunit gamma; AltName: Full=Laminin-10 subunit gamma; AltName: Full=Laminin-11 subunit gamma; AltName: Full=Laminin-2 subunit gamma; AltName: Full=Laminin-3 subunit gamma; AltName: Full=Laminin-4 subunit gamma; AltName: Full=Laminin-6 subunit gamma; AltName: Full=Laminin-7 subunit gamma; AltName: Full=Laminin-8 subunit gamma; AltName: Full=Laminin-9 subunit gamma; AltName: Full=S-laminin subunit gamma; Short=S-LAM gamma; Flags: Precursor 100 0 sp|P11047|LAMC1_HUMAN Laminin subunit gamma-1 OS=Homo sapiens GN=LAMC1 PE=1 SV=3 99.45 0 H9FJH6 H9FJH6_MACMU Laminin subunit gamma-1 (Fragment) OS=Macaca mulatta GN=LAMC1 PE=2 SV=1 BH0876_2 55.5 7.00E-07 COG0840 Methyl-accepting chemotaxis protein NT Cell motility ; Signal transduction mechanisms ; K05635|1|0.0|3048|hsa:3915|laminin, gamma 1 GO:0016477//cell migration;GO:0007411//axon guidance;GO:0022617//extracellular matrix disassembly;GO:0050679//positive regulation of epithelial cell proliferation;GO:0031581//hemidesmosome assembly;GO:0007492//endoderm development;GO:0006461//protein complex assembly;GO:0034446//substrate adhesion-dependent cell spreading GO:0043208//glycosphingolipid binding;GO:0005201//extracellular matrix structural constituent GO:0043260//laminin-11 complex;GO:0005606//laminin-1 complex;GO:0005615//extracellular space;GO:0043259//laminin-10 complex 236 tr|B3KQQ9|B3KQQ9_HUMAN cDNA PSEC0048 fis, clone NT2RP2000028, highly similar to Serine protease 23 OS=Homo sapiens PE=2 SV=1 53584 MAGIPGLLFLLFFLLCAVGQVSPYSAPWKPTWPAYRLPVVLPQSTLNLAKPDFGAEAKLEVSSSCGPQCHKGTPLPTYEEAKQYLSYETLYANGSRTETQVGIYILSSSGDGAQHRDSGSSGKSRRKRQIYGYDSRFSIFGKDFLLNYPFSTSVKLSTGCTGTLVAEKHVLTAAHCIHDGKTYVKGTQKLRVGFLKPKFKDGGRGANDSTSAMPEQMKFQWIRVKRTHVPKGWIKGNANDIGMDYDYALLELKKPHKRKFMKIGVSPPAKQLPGDRIHFSGYDNDRPGNLVYRFCDVKDETYDLLYQQCDAQPGASGSGVYVRMWKRQQQKWERKIIGIFSGHQWVDMNGSPQDFNVAVRITPLKYAQICYWIKGNYLDCREG 851 23 1 32 32 6 6 0.987 0.669 0.759 25 25 24 - - * 0.805 0.163914612 tr|B3KQQ9|B3KQQ9_HUMAN 100 0 gi|193786798|dbj|BAG52121.1| unnamed protein product [Homo sapiens] 99.74 0 sp|O95084|PRS23_HUMAN Serine protease 23 OS=Homo sapiens GN=PRSS23 PE=1 SV=1 100 0 B3KQQ9 B3KQQ9_HUMAN cDNA PSEC0048 fis, clone NT2RP2000028, highly similar to Serine protease 23 OS=Homo sapiens PE=2 SV=1 - - - - - - - K09627|1|0.0|745|hsa:11098|protease, serine, 23 [EC:3.4.21.-] GO:0006508//proteolysis GO:0004252//serine-type endopeptidase activity GO:0005576//extracellular region;GO:0005634//nucleus 237 tr|F4ZW64|F4ZW64_HUMAN NF90a OS=Homo sapiens PE=2 SV=1 94013 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQAESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETGAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSDFFTDCYGYHDFGSS 197 6.4 4 11 11 4 4 1.289 1.055 1.238 7 7 7 - - - 1.194 0.123048771 tr|F4ZW64|F4ZW64_HUMAN 100 0 gi|62087704|dbj|BAD92299.1| interleukin enhancer binding factor 3 isoform c variant [Homo sapiens] 99.84 0 sp|Q12906|ILF3_HUMAN Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3 PE=1 SV=3 100 0 F4ZW64 F4ZW64_HUMAN NF90a OS=Homo sapiens PE=2 SV=1 - - - - - - - K13090|1|0.0|1113|hsa:3609|interleukin enhancer-binding factor 3 GO:0000279//M phase;GO:0045892//negative regulation of transcription, DNA-dependent;GO:0045893//positive regulation of transcription, DNA-dependent GO:0003677//DNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0030529//ribonucleoprotein complex 238 tr|A0A087WVQ6|A0A087WVQ6_HUMAN Clathrin heavy chain OS=Homo sapiens GN=CLTC PE=1 SV=1 223516 MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKGIKESGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDEEPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNFSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGYTAPPYGQPQPGFGYSM 897 14.5 1 49 49 19 19 0.736 0.697 0.686 33 34 33 * - * 0.706333333 0.026274195 tr|A0A087WVQ6|A0A087WVQ6_HUMAN 100 0 gi|119614803|gb|EAW94397.1| clathrin, heavy polypeptide (Hc), isoform CRA_c [Homo sapiens] 99.7 0 sp|P49951|CLH1_BOVIN 99.94 0 G7PUH3 G7PUH3_MACFA Putative uncharacterized protein OS=Macaca fascicularis GN=EGM_07783 PE=4 SV=1 - - - - - - - K04646|1|0.0|3393|ecb:100057364|clathrin heavy chain GO:0007411//axon guidance;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0033572//transferrin transport;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0016044//cellular membrane organization;GO:0006886//intracellular protein transport;GO:0007030//Golgi organization;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0031623//receptor internalization;GO:0090307//spindle assembly involved in mitosis;GO:0006892//post-Golgi vesicle-mediated transport GO:0030506//ankyrin binding;GO:0005198//structural molecule activity;GO:0008022//protein C-terminus binding;GO:0031072//heat shock protein binding;GO:0042277//peptide binding GO:0030132//clathrin coat of coated pit;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0042470//melanosome;GO:0005829//cytosol;GO:0005819//spindle;GO:0030315//T-tubule;GO:0031523//Myb complex;GO:0005739//mitochondrion 239 sp|P23526|SAHH_HUMAN Adenosylhomocysteinase OS=Homo sapiens GN=AHCY PE=1 SV=4 57382 MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY 126 5.3 - 4 4 2 2 1.136 0.75 0.646 4 3 4 - * - 0.844 0.258170486 sp|P23526|SAHH_HUMAN 100 2.00E-160 gi|119596687|gb|EAW76281.1| S-adenosylhomocysteine hydrolase, isoform CRA_b [Homo sapiens] 100 0 sp|P23526|SAHH_HUMAN Adenosylhomocysteinase OS=Homo sapiens GN=AHCY PE=1 SV=4 100 0 G3SA81 G3SA81_GORGO Adenosylhomocysteinase (Fragment) OS=Gorilla gorilla gorilla GN=AHCY PE=3 SV=1 SPBC8D2.18c 680 0 COG0499 S-adenosylhomocysteine hydrolase H Coenzyme transport and metabolism ; K01251|1|0.0|884|ptr:458190|adenosylhomocysteinase [EC:3.3.1.1] GO:0001666//response to hypoxia;GO:0042745//circadian sleep/wake cycle;GO:0002439//chronic inflammatory response to antigenic stimulus;GO:0006805//xenobiotic metabolic process;GO:0007584//response to nutrient;GO:0019510//S-adenosylhomocysteine catabolic process;GO:0006730//one-carbon metabolic process;GO:0032259//methylation;GO:0034641//cellular nitrogen compound metabolic process;GO:0000096//sulfur amino acid metabolic process GO:0051287//NAD binding;GO:0005507//copper ion binding;GO:0030554//adenyl nucleotide binding;GO:0042802//identical protein binding;GO:0004013//adenosylhomocysteinase activity;GO:0043621//protein self-association GO:0005829//cytosol;GO:0043005//neuron projection;GO:0042470//melanosome;GO:0005634//nucleus 240 tr|B4DEY6|B4DEY6_HUMAN LIM and cysteine-rich domains protein 1 OS=Homo sapiens GN=LMCD1 PE=2 SV=1 34769 MFGMQGDVFGLRATFMEGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 75 13 1 3 3 2 2 0.711 1.362 1.279 3 3 3 - - - 1.117333333 0.354333647 tr|B4DEY6|B4DEY6_HUMAN 100 1.00E-118 gi|119584341|gb|EAW63937.1| LIM and cysteine-rich domains 1, isoform CRA_a [Homo sapiens] 100 3.00E-119 sp|Q9NZU5|LMCD1_HUMAN LIM and cysteine-rich domains protein 1 OS=Homo sapiens GN=LMCD1 PE=1 SV=1 100 2.00E-38 H7C3D2 H7C3D2_HUMAN LIM and cysteine-rich domains protein 1 (Fragment) OS=Homo sapiens GN=LMCD1 PE=4 SV=1 - - - - - - - K04511|1|2e-38|159|dre:368250|prickle GO:0010611//regulation of cardiac muscle hypertrophy;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade GO:0008270//zinc ion binding;GO:0003714//transcription corepressor activity GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0005634//nucleus 241 tr|Q5U000|Q5U000_HUMAN Cathepsin Z OS=Homo sapiens PE=2 SV=1 37573 MARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRIVTSTYKDGKGARYNIAIEEHCTFGDPIV 58 8.9 1 5 5 2 2 0.972 1.048 1.117 3 3 3 - - - 1.045666667 0.072528155 tr|Q5U000|Q5U000_HUMAN 100 6.00E-147 gi|119595856|gb|EAW75450.1| cathepsin Z, isoform CRA_c [Homo sapiens] 99.67 9.00E-170 sp|Q9UBR2|CATZ_HUMAN Cathepsin Z OS=Homo sapiens GN=CTSZ PE=1 SV=1 100 2.00E-97 A5HC51 A5HC51_RABIT Cathepsin Z (Fragment) OS=Oryctolagus cuniculus PE=2 SV=1 AF1946_2 63.2 5.00E-10 COG4870 Cysteine protease O Posttranslational modification, protein turnover, chaperones ; K08568|1|9e-170|595|ptr:736240|cathepsin X [EC:3.4.18.1] GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0006508//proteolysis GO:0004197//cysteine-type endopeptidase activity GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum 242 sp|O43854|EDIL3_HUMAN EGF-like repeat and discoidin I-like domain-containing protein 3 OS=Homo sapiens GN=EDIL3 PE=1 SV=1 63616 MKRSVAVWLLVGLSLGVPQFGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVASDEEEPTSAGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE 197 18.3 - 15 15 8 8 1.303 0.808 0.797 6 6 6 - - - 0.969333333 0.289016147 sp|O43854|EDIL3_HUMAN 100 0 gi|31317224|ref|NP_005702.3| EGF-like repeat and discoidin I-like domain-containing protein 3 precursor [Homo sapiens] >gi|41016967|sp|O43854.1|EDIL3_HUMAN RecName: Full=EGF-like repeat and discoidin I-like domain-containing protein 3; AltName: Full=Developmentally-regulated endothelial cell locus 1 protein; AltName: Full=Integrin-binding protein DEL1; Flags: Precursor >gi|2865219|gb|AAC02648.1| integrin binding protein Del-1 [Homo sapiens] >gi|119616324|gb|EAW95918.1| EGF-like repeats and discoidin I-like domains 3, isoform CRA_c [Homo sapiens] 100 0 sp|O43854|EDIL3_HUMAN EGF-like repeat and discoidin I-like domain-containing protein 3 OS=Homo sapiens GN=EDIL3 PE=1 SV=1 100 7.00E-94 F7H1B6 F7H1B6_CALJA Uncharacterized protein (Fragment) OS=Callithrix jacchus GN=LOC100405071 PE=4 SV=1 - - - - - - - K03902|1|2e-72|273|ecb:100058503|coagulation factor V (labile factor) GO:0010811//positive regulation of cell-substrate adhesion;GO:0007275//multicellular organismal development GO:0005509//calcium ion binding;GO:0005178//integrin binding GO:0005576//extracellular region 243 sp|O15511|ARPC5_HUMAN Actin-related protein 2/3 complex subunit 5 OS=Homo sapiens GN=ARPC5 PE=1 SV=3 20930 MSKNTVSSARFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDNSSAMLLQWHEKALAAGGVGSIVRVLTARKTV 185 11.9 - 10 10 2 2 0.882 1.01 0.761 6 6 3 - - * 0.884333333 0.124516398 sp|O15511|ARPC5_HUMAN 100 1.00E-40 gi|344252595|gb|EGW08699.1| Actin-related protein 2/3 complex subunit 5 [Cricetulus griseus] 100 4.00E-84 sp|Q5R516|ARPC5_PONAB Actin-related protein 2/3 complex subunit 5 OS=Pongo abelii GN=ARPC5 PE=2 SV=3 100 4.00E-40 G3HG16 G3HG16_CRIGR Actin-related protein 2/3 complex subunit 5 OS=Cricetulus griseus GN=I79_009535 PE=3 SV=1 - - - - - - - K05754|1|4e-84|309|ssc:100174965|actin related protein 2/3 complex, subunit 5 GO:0030833//regulation of actin filament polymerization;GO:0006928//cellular component movement GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton GO:0005885//Arp2/3 protein complex;GO:0030027//lamellipodium;GO:0005737//cytoplasm 244 tr|A0A087WZV1|A0A087WZV1_HUMAN Heterogeneous nuclear ribonucleoprotein A/B OS=Homo sapiens GN=HNRNPAB PE=1 SV=1 45776 MSEAGEEQPMETTGATENGHEAVPEASRGRGWTGAAAGLEARPRRPRAGIRTAPRDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY 144 12.1 5 13 9 4 3 1.153 0.731 0.836 3 3 3 - - - 0.906666667 0.219696002 tr|A0A087WZV1|A0A087WZV1_HUMAN 100 2.00E-81 gi|397467431|ref|XP_003805422.1| PREDICTED: heterogeneous nuclear ribonucleoprotein A/B [Pan paniscus] 92.74 3.00E-107 sp|Q99729|ROAA_HUMAN Heterogeneous nuclear ribonucleoprotein A/B OS=Homo sapiens GN=HNRNPAB PE=1 SV=2 99.39 3.00E-81 G1S0T3 G1S0T3_NOMLE Uncharacterized protein (Fragment) OS=Nomascus leucogenys GN=HNRNPAB PE=4 SV=1 SPAC140.02 87.4 3.00E-17 COG0724 RNA-binding proteins (RRM domain) R General function prediction only ; K13044|1|1e-102|373|hsa:3182|heterogeneous nuclear ribonucleoprotein A/B/D GO:0001837//epithelial to mesenchymal transition;GO:0045893//positive regulation of transcription, DNA-dependent GO:0003729//mRNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000166//nucleotide binding GO:0030529//ribonucleoprotein complex;GO:0005737//cytoplasm;GO:0005634//nucleus 245 sp|P36222|CH3L1_HUMAN Chitinase-3-like protein 1 OS=Homo sapiens GN=CHI3L1 PE=1 SV=2 >tr|A0A024R969|A0A024R969_HUMAN Chitinase 3-like 1 (Cartilage glycoprotein-39), isoform CRA_a OS=Homo sapiens GN=CHI3L1 PE=3 SV=1 49690 MGVKASQTGFVVLVLLQCCSAYKLVCYYTSWSQYREGDGSCFPDALDRFLCTHIIYSFANISNDHIDTWEWNDVTLYGMLNTLKNRNPNLKTLLSVGGWNFGSQRFSKIASNTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGRRDKQHFTTLIKEMKAEFIKEAQPGKKQLLLSAALSAGKVTIDSSYDIAKISQHLDFISIMTYDFHGAWRGTTGHHSPLFRGQEDASPDRFSNTDYAVGYMLRLGAPASKLVMGIPTFGRSFTLASSETGVGAPISGPGIPGRFTKEAGTLAYYEICDFLRGATVHRILGQQVPYATKGNQWVGYDDQESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQDLRFPLTNAIKDALAAT 407 24.8 - 21 21 8 8 1.93 1.922 1.829 11 7 6 - - - 1.893666667 0.056145644 sp|P36222|CH3L1_HUMAN 100 0 gi|144226251|ref|NP_001267.2| chitinase-3-like protein 1 precursor [Homo sapiens] >gi|84028186|sp|P36222.2|CH3L1_HUMAN RecName: Full=Chitinase-3-like protein 1; AltName: Full=39 kDa synovial protein; AltName: Full=Cartilage glycoprotein 39; Short=CGP-39; Short=GP-39; Short=hCGP-39; AltName: Full=YKL-40; Flags: Precursor >gi|14919433|gb|AAH08568.1| Chitinase 3-like 1 (cartilage glycoprotein-39) [Homo sapiens] >gi|30583285|gb|AAP35887.1| chitinase 3-like 1 (cartilage glycoprotein-39) [Homo sapiens] >gi|119611873|gb|EAW91467.1| chitinase 3-like 1 (cartilage glycoprotein-39), isoform CRA_a [Homo sapiens] >gi|119611874|gb|EAW91468.1| chitinase 3-like 1 (cartilage glycoprotein-39), isoform CRA_a [Homo sapiens] 100 0 sp|P36222|CH3L1_HUMAN Chitinase-3-like protein 1 OS=Homo sapiens GN=CHI3L1 PE=1 SV=2 99.48 0 H2Q0Y0 H2Q0Y0_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000133048 PE=3 SV=1 BH0916_1 162 1.00E-39 COG3325 Chitinase G Carbohydrate transport and metabolism ; K01183|1|0.0|781|hsa:1116|chitinase [EC:3.2.1.14] GO:0030324//lung development;GO:0071347//cellular response to interleukin-1;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071356//cellular response to tumor necrosis factor;GO:0009612//response to mechanical stimulus;GO:0072606//interleukin-8 secretion;GO:0045766//positive regulation of angiogenesis;GO:0051216//cartilage development;GO:0006032//chitin catabolic process;GO:0005975//carbohydrate metabolic process;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0006954//inflammatory response;GO:0070741//response to interleukin-6;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0051897//positive regulation of protein kinase B signaling cascade GO:0004568//chitinase activity;GO:0005201//extracellular matrix structural constituent;GO:0008061//chitin binding;GO:0043169//cation binding GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0005783//endoplasmic reticulum 246 tr|A0A087X271|A0A087X271_HUMAN Calponin (Fragment) OS=Homo sapiens GN=CNN2 PE=1 SV=1 24783 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQVQAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSGMTAYGTRR 250 27.9 6 10 5 4 3 0.955 0.974 0.752 5 4 5 - - * 0.893666667 0.123054189 tr|A0A087X271|A0A087X271_HUMAN 98.88 3.00E-99 gi|194375540|dbj|BAG56715.1| unnamed protein product [Homo sapiens] 95.21 1.00E-100 sp|Q5RFN6|CNN2_PONAB Calponin-2 OS=Pongo abelii GN=CNN2 PE=2 SV=3 98.88 9.00E-99 B4DDF4 B4DDF4_HUMAN Calponin-2 OS=Homo sapiens GN=CNN2 PE=2 SV=1 ECU03g1150 72.4 4.00E-13 COG5199 Calponin Z Cytoskeleton ; K06084|1|3e-13|75.1|bfo:BRAFLDRAFT_117217|F-box protein 20 GO:0042060//wound healing;GO:0031032//actomyosin structure organization;GO:0030336//negative regulation of cell migration;GO:0050765//negative regulation of phagocytosis;GO:0030097//hemopoiesis;GO:0032970//regulation of actin filament-based process;GO:0010628//positive regulation of gene expression;GO:0042127//regulation of cell proliferation;GO:0071260//cellular response to mechanical stimulus GO:0005516//calmodulin binding;GO:0003779//actin binding GO:0001725//stress fiber;GO:0005911//cell-cell junction 247 tr|E7EUF1|E7EUF1_HUMAN Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 OS=Homo sapiens GN=ENPP2 PE=4 SV=1 121261 MTRHADRIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEAETRKFRGSRNENKENINGNFEPRKERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 994 24.2 1 63 63 16 16 1.228 1.405 1.6 38 36 35 * * - 1.411 0.186072566 tr|E7EUF1|E7EUF1_HUMAN 99.89 0 gi|195947389|ref|NP_001124335.1| ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform 3 preproprotein [Homo sapiens] 97.04 0 sp|Q13822|ENPP2_HUMAN Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 OS=Homo sapiens GN=ENPP2 PE=1 SV=3 100 0 E7EUF1 E7EUF1_HUMAN Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 OS=Homo sapiens GN=ENPP2 PE=4 SV=1 SPBC725.05c 215 2.00E-55 COG1524 Uncharacterized proteins of the AP superfamily R General function prediction only ; K01122|1|0.0|1807|pon:100173553|ectonucleotide pyrophosphatase/phosphodiesterase family member 2 [EC:3.1.4.39] GO:0006935//chemotaxis;GO:0006955//immune response;GO:0030334//regulation of cell migration;GO:0034638//phosphatidylcholine catabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0007186//G-protein coupled receptor signaling pathway GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding;GO:0005509//calcium ion binding;GO:0030247//polysaccharide binding;GO:0004528//phosphodiesterase I activity;GO:0047391//alkylglycerophosphoethanolamine phosphodiesterase activity;GO:0005044//scavenger receptor activity;GO:0008134//transcription factor binding;GO:0004551//nucleotide diphosphatase activity;GO:0004622//lysophospholipase activity GO:0005615//extracellular space;GO:0005887//integral to plasma membrane 248 tr|B2R7D2|B2R7D2_HUMAN cDNA, FLJ93389, highly similar to Homo sapiens multiple inositol polyphosphate histidine phosphatase, 1 (MINPP1), mRNA OS=Homo sapiens PE=2 SV=1 64534 MLRAPGCLLRTSVAPAAALAAALLSSLARCSLLEPRDPVASSLSPYFGTKTRYEDVNPVLLSGPEAPWRDPELLEGTCTPVQLVALIRHGTRYPTVKQIRKLRQLHGLLQARGSRDGGASRTGSRDLGAALADWPLWYADWMDGQLVEKGRQDMRQLALRLASLFPALFSRENYGRLRLITSSKHRCMDSSAAFLQGLWQHYHPGLPPPDVADMEFGPPTVNDKLMRFFDHCEKFLTEVEKNATALYHVEAFKTGPEMQNILKKVAATLQVPVNDLNADLIQVAFFTCSFDLAIKGVKSPWCDVFDIDDAKVLEYLNDLKQYWKRGYGYTINSRSSCTLFQDIFQHLDKAVEQKQRSQPISSPVILQFGHAETLLPLLSLMGYFKDKEPLTAYNYKKQMHRKFRSGLIVPYASNLIFVLYHCENAKTPKEQFRVQMLLNEKVLPLAYSQETVSFYEDLKNHYKDILQSCQTSEECELARANSTSDEL 74 4.9 2 2 2 2 2 0.762 0.752 --- 2 2 1 - - - 0.757 0.007071068 tr|B2R7D2|B2R7D2_HUMAN 100 0 gi|194388044|dbj|BAG65406.1| unnamed protein product [Homo sapiens] 99.79 0 sp|Q9UNW1|MINP1_HUMAN Multiple inositol polyphosphate phosphatase 1 OS=Homo sapiens GN=MINPP1 PE=1 SV=1 100 4.00E-161 F5H683 F5H683_HUMAN Multiple inositol polyphosphate phosphatase 1 OS=Homo sapiens GN=MINPP1 PE=4 SV=1 - - - - - - - K03103|1|0.0|957|ptr:450579|multiple inositol-polyphosphate phosphatase [EC:3.1.3.62] GO:0030282//bone mineralization;GO:0016311//dephosphorylation;GO:0006797//polyphosphate metabolic process GO:0003993//acid phosphatase activity;GO:0052826//inositol hexakisphosphate 2-phosphatase activity;GO:0034417//bisphosphoglycerate 3-phosphatase activity;GO:0030352//inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity;GO:0030351//inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity;GO:0008969//phosphohistidine phosphatase activity GO:0005788//endoplasmic reticulum lumen 249 tr|C9J8S2|C9J8S2_HUMAN Retinoic acid receptor responder protein 2 (Fragment) OS=Homo sapiens GN=RARRES2 PE=4 SV=1 21794 MRRLLIPLALWLGAVGVGVAELTEAQRRGLQVALEEFHKHPPVQWAFQETSVESAVDTPFPAGIFVRLEFKLQQTSCRKRDWKKPECKVRPNGRKRKCLACIKLGSEDKVLGRLVHCPIETQVLRRCVVPPGPLRVVTSGRPQPPGRGTRSIPSHDNKA 151 14.5 1 9 9 2 2 2.232 2.583 1.593 6 5 5 * * - 2.136 0.501933262 tr|C9J8S2|C9J8S2_HUMAN 100 2.00E-66 gi|197100983|ref|NP_001127631.1| retinoic acid receptor responder protein 2 precursor [Pongo abelii] >gi|62901215|sp|Q5R551.1|RARR2_PONAB RecName: Full=Retinoic acid receptor responder protein 2; Flags: Precursor 100 1.00E-67 sp|Q99969|RARR2_HUMAN Retinoic acid receptor responder protein 2 OS=Homo sapiens GN=RARRES2 PE=1 SV=1 100 4.00E-66 Q7LE02 Q7LE02_HUMAN Putative uncharacterized protein RARRES2 OS=Homo sapiens GN=RARRES2 PE=2 SV=1 - - - - - - - K10044|1|1e-67|254|ptr:735446|retinoic acid receptor responder protein 2 GO:0050873//brown fat cell differentiation;GO:0048566//embryonic digestive tract development;GO:0001523//retinoid metabolic process;GO:0001701//in utero embryonic development;GO:0010759//positive regulation of macrophage chemotaxis GO:0005102//receptor binding GO:0031012//extracellular matrix;GO:0005576//extracellular region 250 tr|A8KAP9|A8KAP9_HUMAN cDNA FLJ78448, highly similar to Homo sapiens argininosuccinate synthetase (ASS), transcript variant 1, mRNA OS=Homo sapiens PE=2 SV=1 57153 MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWSMDENLMHISYEAGILENPKNQAPPGHYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKDGTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYILGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK 152 7 1 4 4 2 2 1.315 0.836 1.301 3 3 3 - - - 1.150666667 0.272599217 tr|A8KAP9|A8KAP9_HUMAN 100 1.00E-20 gi|85540932|gb|ABC70851.1| CN [Bos taurus] 99.76 0 sp|P00966|ASSY_HUMAN Argininosuccinate synthase OS=Homo sapiens GN=ASS1 PE=1 SV=2 100 0 A8KAP9 A8KAP9_HUMAN cDNA FLJ78448, highly similar to Homo sapiens argininosuccinate synthetase (ASS), transcript variant 1, mRNA OS=Homo sapiens PE=2 SV=1 TM1780 496 3.00E-140 COG0137 Argininosuccinate synthase E Amino acid transport and metabolism ; K01940|1|0.0|832|hsa:445|argininosuccinate synthase [EC:6.3.4.5] GO:0000050//urea cycle;GO:0071400//cellular response to oleic acid;GO:0001822//kidney development;GO:0071549//cellular response to dexamethasone stimulus;GO:0071356//cellular response to tumor necrosis factor;GO:0010046//response to mycotoxin;GO:0007568//aging;GO:0071242//cellular response to ammonium ion;GO:0007494//midgut development;GO:0060416//response to growth hormone stimulus;GO:0006526//arginine biosynthetic process;GO:0071377//cellular response to glucagon stimulus;GO:0006953//acute-phase response;GO:0010043//response to zinc ion;GO:0042493//response to drug;GO:0071320//cellular response to cAMP;GO:0071346//cellular response to interferon-gamma;GO:0001889//liver development;GO:0071222//cellular response to lipopolysaccharide;GO:0000053//argininosuccinate metabolic process;GO:0060539//diaphragm development;GO:0071230//cellular response to amino acid stimulus;GO:0007584//response to nutrient;GO:0032355//response to estradiol stimulus GO:0005515//protein binding;GO:0015643//toxic substance binding;GO:0004055//argininosuccinate synthase activity;GO:0005524//ATP binding GO:0070852//cell body fiber;GO:0005764//lysosome;GO:0005829//cytosol;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005634//nucleus;GO:0043204//perikaryon 251 sp|P28799|GRN_HUMAN Granulins OS=Homo sapiens GN=GRN PE=1 SV=2 73689 MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSCCRPLLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPALRQLL 244 24.1 - 21 21 10 10 1.053 0.772 1.357 12 13 13 - * - 1.060666667 0.292575346 sp|P28799|GRN_HUMAN 100 3.00E-25 gi|185177523|pdb|2JYE|A Chain A, Human Granulin A 100 0 sp|P28799|GRN_HUMAN Granulins OS=Homo sapiens GN=GRN PE=1 SV=2 99.83 0 Q53HQ8 Q53HQ8_HUMAN Granulin variant (Fragment) OS=Homo sapiens PE=2 SV=1 - - - - - - - - GO:0050679//positive regulation of epithelial cell proliferation;GO:0007165//signal transduction;GO:0007566//embryo implantation;GO:0001835//blastocyst hatching GO:0008083//growth factor activity;GO:0005125//cytokine activity GO:0005615//extracellular space;GO:0005739//mitochondrion 252 tr|A8K7F6|A8K7F6_HUMAN cDNA FLJ78244, highly similar to Homo sapiens eukaryotic translation initiation factor 4A, isoform 1 (EIF4A1), mRNA OS=Homo sapiens PE=2 SV=1 52709 MSASQDSRSRDNGPDGVEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 164 14.5 1 15 6 5 1 0.844 1.025 0.527 5 5 5 - - - 0.798666667 0.252076047 tr|A8K7F6|A8K7F6_HUMAN 100 1.00E-159 gi|74212599|dbj|BAE31038.1| unnamed protein product [Mus musculus] 99.75 0 sp|P29562|IF4A1_RABIT Eukaryotic initiation factor 4A-I (Fragment) OS=Oryctolagus cuniculus GN=EIF4A1 PE=1 SV=2 100 4.00E-159 Q3U8I0 Q3U8I0_MOUSE Putative uncharacterized protein OS=Mus musculus GN=Eif4a1 PE=2 SV=1 SPAC1006.07 586 2.00E-167 COG0513 Superfamily II DNA and RNA helicases LKJ Replication, recombination and repair ; Transcription ; Translation, ribosomal structure and biogenesis ; K03257|1|0.0|810|cfa:100688577|translation initiation factor 4A GO:0006413//translational initiation;GO:0031100//organ regeneration;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0019221//cytokine-mediated signaling pathway;GO:0019048//virus-host interaction GO:0003743//translation initiation factor activity;GO:0003729//mRNA binding;GO:0008026//ATP-dependent helicase activity;GO:0000339//RNA cap binding;GO:0005524//ATP binding;GO:0005515//protein binding GO:0016281//eukaryotic translation initiation factor 4F complex;GO:0005829//cytosol 253 sp|P01034|CYTC_HUMAN Cystatin-C OS=Homo sapiens GN=CST3 PE=1 SV=1 18451 MAGPLRAPLLLLAILAVALAVSPAAGSSPGKPPRLVGGPMDASVEEEGVRRALDFAVGEYNKASNDMYHSRALQVVRARKQIVAGVNYFLDVELGRTTCTKTQPNLDNCPFHDQPHLKRKAFCSFQIYAVPWQGTMTLSKSTCQDA 568 32.9 - 31 31 3 3 1.543 1.407 1.76 20 21 21 - * * 1.57 0.17804213 sp|P01034|CYTC_HUMAN 100 7.00E-63 gi|14278690|pdb|1G96|A Chain A, Human Cystatin C; Dimeric Form With 3d Domain Swapping >gi|73535285|pdb|1TIJ|A Chain A, 3d Domain-Swapped Human Cystatin C With Amyloid-Like Intermolecular Beta-Sheets >gi|73535286|pdb|1TIJ|B Chain B, 3d Domain-Swapped Human Cystatin C With Amyloid-Like Intermolecular Beta-Sheets 100 2.00E-64 sp|P01034|CYTC_HUMAN Cystatin-C OS=Homo sapiens GN=CST3 PE=1 SV=1 100 7.00E-63 H2P181 H2P181_PONAB Uncharacterized protein OS=Pongo abelii GN=CST3 PE=4 SV=1 - - - - - - - K13899|1|2e-64|243|hsa:1471|cystatin-C GO:0010711//negative regulation of collagen catabolic process;GO:0060548//negative regulation of cell death;GO:0010951//negative regulation of endopeptidase activity;GO:0070301//cellular response to hydrogen peroxide;GO:0043067//regulation of programmed cell death;GO:0006915//apoptotic process;GO:0042747//circadian sleep/wake cycle, REM sleep;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0008284//positive regulation of cell proliferation;GO:0007420//brain development;GO:0014070//response to organic cyclic compound;GO:0001654//eye development;GO:0001666//response to hypoxia;GO:0048678//response to axon injury;GO:0007566//embryo implantation;GO:0042493//response to drug;GO:0060009//Sertoli cell development;GO:0009636//response to toxic substance;GO:0043206//extracellular fibril organization;GO:0001775//cell activation;GO:0007431//salivary gland development;GO:0045740//positive regulation of DNA replication;GO:0060313//negative regulation of blood vessel remodeling;GO:0009743//response to carbohydrate stimulus;GO:0006952//defense response;GO:0010703//negative regulation of histolysis;GO:0032355//response to estradiol stimulus;GO:0031667//response to nutrient levels;GO:0060311//negative regulation of elastin catabolic process GO:0001540//beta-amyloid binding;GO:0002020//protease binding;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0005604//basement membrane;GO:0031982//vesicle;GO:0031965//nuclear membrane;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0043025//neuronal cell body;GO:0005771//multivesicular body;GO:0048471//perinuclear region of cytoplasm;GO:0033267//axon part;GO:0005783//endoplasmic reticulum;GO:0043292//contractile fiber 254 tr|A0A087WTT1|A0A087WTT1_HUMAN Polyadenylate-binding protein 1 OS=Homo sapiens GN=PABPC1 PE=1 SV=1 71199 MLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV 199 20.9 2 14 13 9 8 0.965 0.847 1.046 9 9 9 - - - 0.952666667 0.100071641 tr|A0A087WTT1|A0A087WTT1_HUMAN 99.81 0 gi|693937|emb|CAA88401.1| polyadenylate binding protein II [Homo sapiens] 98.83 0 sp|Q5R8F7|PABP1_PONAB Polyadenylate-binding protein 1 OS=Pongo abelii GN=PABPC1 PE=2 SV=1 100 0 H9Z7Q3 H9Z7Q3_MACMU Polyadenylate-binding protein 1 OS=Macaca mulatta GN=PABPC1 PE=2 SV=1 YCL011c 83.2 9.00E-16 COG0724 RNA-binding proteins (RRM domain) R General function prediction only ; K13126|1|0.0|967|ptr:452494|polyadenylate-binding protein GO:0006413//translational initiation;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006378//mRNA polyadenylation;GO:0000398//mRNA splicing, via spliceosome;GO:0048255//mRNA stabilization;GO:2000623//negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0045727//positive regulation of translation GO:0008494//translation activator activity;GO:0008022//protein C-terminus binding;GO:0008143//poly(A) RNA binding;GO:0000166//nucleotide binding GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0071013//catalytic step 2 spliceosome 255 tr|G3XAI2|G3XAI2_HUMAN Laminin subunit beta-1 OS=Homo sapiens GN=LAMB1 PE=1 SV=1 233864 MDCPLSAPTPPPPLVRFFRAPLPACVPPTLLPVLPAALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEGAYLEFFIDNIPYSMEYDILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNTIPDDDNQVVSLSPGSRYVVLPRPVCFEKGTNYTVRLELPQYTSSDSDVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGVVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLLKDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAVYSTCL 1628 13.4 1 77 77 18 18 1.651 1.858 1.579 48 50 46 - - * 1.696 0.144841292 tr|G3XAI2|G3XAI2_HUMAN 100 0 gi|119603829|gb|EAW83423.1| laminin, beta 1, isoform CRA_a [Homo sapiens] 100 0 sp|P07942|LAMB1_HUMAN Laminin subunit beta-1 OS=Homo sapiens GN=LAMB1 PE=1 SV=2 100 0 E7EPA6 E7EPA6_HUMAN Laminin subunit beta-1 OS=Homo sapiens GN=LAMB1 PE=4 SV=1 TM1428 56.2 6.00E-07 COG0840 Methyl-accepting chemotaxis protein NT Cell motility ; Signal transduction mechanisms ; K05636|1|0.0|3583|hsa:3912|laminin, beta 1 GO:0042476//odontogenesis;GO:0007411//axon guidance;GO:0007566//embryo implantation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0007162//negative regulation of cell adhesion;GO:0034446//substrate adhesion-dependent cell spreading;GO:0030335//positive regulation of cell migration GO:0043208//glycosphingolipid binding;GO:0019899//enzyme binding;GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent GO:0005606//laminin-1 complex;GO:0005615//extracellular space;GO:0043257//laminin-8 complex;GO:0048471//perinuclear region of cytoplasm;GO:0043259//laminin-10 complex;GO:0005607//laminin-2 complex 256 tr|J3QRS3|J3QRS3_HUMAN Myosin regulatory light chain 12A OS=Homo sapiens GN=MYL12A PE=4 SV=1 25064 MDLTTTMSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD 152 15.8 3 6 4 2 1 0.573 0.723 0.755 2 2 2 - * - 0.683666667 0.097166524 tr|J3QRS3|J3QRS3_HUMAN 100 2.00E-88 gi|73961895|ref|XP_848839.1| PREDICTED: myosin regulatory light polypeptide 9-like isoform 1 [Canis lupus familiaris] >gi|466039247|ref|XP_004275975.1| PREDICTED: myosin regulatory light polypeptide 9-like isoform 1 [Orcinus orca] >gi|470603766|ref|XP_004313160.1| PREDICTED: myosin regulatory light polypeptide 9-like isoform 1 [Tursiops truncatus] 100 4.00E-89 sp|P19105|ML12A_HUMAN Myosin regulatory light chain 12A OS=Homo sapiens GN=MYL12A PE=1 SV=2 100 7.00E-88 G3W9Q9 G3W9Q9_SARHA Uncharacterized protein OS=Sarcophilus harrisii GN=MYL12B PE=4 SV=1 ECU03g1570 112 4.00E-25 COG5126 Ca2+-binding protein (EF-Hand superfamily) TZDR Signal transduction mechanisms ; Cytoskeleton ; Cell cycle control, cell division, chromosome partitioning ; General function prediction only ; K12757|1|9e-90|328|pon:100172271|myosin regulatory light chain 12 GO:0008360//regulation of cell shape;GO:0072661//protein targeting to plasma membrane GO:0005509//calcium ion binding;GO:0035254//glutamate receptor binding GO:0030018//Z disc;GO:0001725//stress fiber;GO:0016460//myosin II complex 257 tr|A0A024R644|A0A024R644_HUMAN Ceroid-lipofuscinosis neuronal protein 5 OS=Homo sapiens GN=CLN5 PE=4 SV=1 53762 MRRNLRLGPSSGADAQGQGAPRPGLAAPRMLLPPASQASRGSGSTGCSLMAQEVDTAQGAEMRRGAGAARGRASWCWALALLWLAVVPGWSRVSGIPSRRHWPVPYKRFDFRPKPDPYCQAKYTFCPTGSPIPVMEGDDDIEVFRLQAPVWEFKYGDLLGHLKIMHDAIGFRSTLTGKNYTMEWYELFQLGNCTFPHLRPEMDAPFWCNQGAACFFEGIDDVHWKENGTLVQVATISGNMFNQMAKWVKQDNETGIYYETWNVKASPEKGAETWFDSYDCSKFVLRTFNKLAEFGAEFKNIETNYTRIFLYSGEPTYLGNETSVFGPTGNKTLGLAIKRFYYPFKPHLPTKEFLLSLLQIFDAVIVHKQFYLFYNFEYWFLPMKFPFIKITYEEIPLPIRNKTLSGL 143 9.8 2 11 11 4 4 1.698 0.993 1.618 5 4 5 - - * 1.436333333 0.386015975 tr|A0A024R644|A0A024R644_HUMAN 100 0 gi|187608866|sp|O75503.2|CLN5_HUMAN RecName: Full=Ceroid-lipofuscinosis neuronal protein 5; Short=Protein CLN5; Flags: Precursor 100 0 sp|O75503|CLN5_HUMAN Ceroid-lipofuscinosis neuronal protein 5 OS=Homo sapiens GN=CLN5 PE=1 SV=2 100 9.00E-161 B4E1V6 B4E1V6_HUMAN Ceroid-lipofuscinosis neuronal protein 5 OS=Homo sapiens GN=CLN5 PE=2 SV=1 - - - - - - - K12390|1|0.0|778|hsa:1203|ceroid-lipofuscinosis neuronal protein 5 GO:0006465//signal peptide processing;GO:0008219//cell death;GO:0007420//brain development;GO:0070085//glycosylation;GO:0007042//lysosomal lumen acidification;GO:0042551//neuron maturation;GO:0007601//visual perception;GO:0030163//protein catabolic process GO:0005537//mannose binding;GO:0005515//protein binding GO:0005765//lysosomal membrane;GO:0016021//integral to membrane;GO:0005775//vacuolar lumen;GO:0048471//perinuclear region of cytoplasm;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum 258 tr|A0A024R889|A0A024R889_HUMAN Spectrin, alpha, non-erythrocytic 1 (Alpha-fodrin), isoform CRA_g OS=Homo sapiens GN=SPTAN1 PE=4 SV=1 342803 MDPSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQIASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKAPIVTSEELGQDLEHVEVLQKKFEEFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGKLFGAAEVQRFNRDVDETISWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKVKALCAEADRLQQSHPLSATQIQVKREELITNWEQIRTLAAERHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELASDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLAAGHYASDEVREKLTVLSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKDEVAARMNEVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQEQIDNQYHSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDMDDEESWIKEKKLLVGSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHVQSKAIEARHASLMKRWSQLLANSAARKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQEYMAFMISRETENVKSSEEIESAFRALSSEGKPYVTKEELYQNLTREQADYCVSHMKPYVDGKGRELPTAFDYVEFTRSLFVN 630 14.6 1 48 48 30 30 0.773 0.726 0.668 31 31 28 * * * 0.722333333 0.052595944 tr|A0A024R889|A0A024R889_HUMAN 100 0 gi|119608211|gb|EAW87805.1| spectrin, alpha, non-erythrocytic 1 (alpha-fodrin), isoform CRA_a [Homo sapiens] 99.11 0 sp|Q13813|SPTN1_HUMAN 99.92 0 Q9UG16 Q9UG16_HUMAN Putative uncharacterized protein DKFZp564P0562 (Fragment) OS=Homo sapiens GN=DKFZp564P0562 PE=2 SV=1 SPAC3A12.14 62.4 1.00E-08 COG5126 Ca2+-binding protein (EF-Hand superfamily) TZDR Signal transduction mechanisms ; Cytoskeleton ; Cell cycle control, cell division, chromosome partitioning ; General function prediction only ; K06114|1|0.0|4826|hsa:6709|spectrin alpha GO:0007411//axon guidance;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0051693//actin filament capping GO:0030507//spectrin binding;GO:0005509//calcium ion binding;GO:0046982//protein heterodimerization activity;GO:0003779//actin binding;GO:0005516//calmodulin binding;GO:0005200//structural constituent of cytoskeleton GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0008091//spectrin;GO:0005829//cytosol;GO:0016328//lateral plasma membrane;GO:0032437//cuticular plate;GO:0030018//Z disc;GO:0005916//fascia adherens 259 sp|O00391|QSOX1_HUMAN Sulfhydryl oxidase 1 OS=Homo sapiens GN=QSOX1 PE=1 SV=3 93667 MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFFARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIYMADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKRQKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAARQNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSSHNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNIILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEGPEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKNRLWGPLEVRRVGRSSKQLVDIPEGQLEARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLSFMGLLAMYTYFQAKIRALKGHAGHPAA 1306 33.6 - 82 82 18 18 0.817 0.991 0.79 46 48 45 * - - 0.866 0.109091705 sp|O00391|QSOX1_HUMAN 100 2.00E-153 gi|291463663|pdb|3LLI|A Chain A, Sulfhydryl Oxidase Fragment Of Human Qsox1 >gi|292659740|pdb|3LLK|A Chain A, Sulfhydryl Oxidase Fragment Of Human Qsox1 >gi|292659741|pdb|3LLK|B Chain B, Sulfhydryl Oxidase Fragment Of Human Qsox1 >gi|292659742|pdb|3LLK|C Chain C, Sulfhydryl Oxidase Fragment Of Human Qsox1 100 0 sp|O00391|QSOX1_HUMAN Sulfhydryl oxidase 1 OS=Homo sapiens GN=QSOX1 PE=1 SV=3 99.5 0 A8K477 A8K477_HUMAN cDNA FLJ78571, highly similar to Homo sapiens sulfhydryl oxidase mRNA OS=Homo sapiens PE=2 SV=1 YCL043c 63.2 2.00E-09 COG0526 Thiol-disulfide isomerase and thioredoxins OC Posttranslational modification, protein turnover, chaperones ; Energy production and conversion ; K10758|1|0.0|1219|hsa:5768|thiol oxidase [EC:1.8.3.2] GO:0045454//cell redox homeostasis;GO:0006662//glycerol ether metabolic process GO:0009055//electron carrier activity;GO:0016971//flavin-linked sulfhydryl oxidase activity;GO:0015035//protein disulfide oxidoreductase activity GO:0005615//extracellular space;GO:0030173//integral to Golgi membrane 260 tr|Q53GF5|Q53GF5_HUMAN Proteasome subunit alpha type (Fragment) OS=Homo sapiens PE=2 SV=1 30501 MAERGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLELEDAIHTAILTLKESFEGQMTEDNIEVGICNEAGFRRLTPTEVKGYLAAIA 73 15.4 1 4 4 2 2 1.292 0.56 --- 2 2 1 - - - 0.926 0.517602164 tr|Q53GF5|Q53GF5_HUMAN 100 1.00E-53 gi|119614557|gb|EAW94151.1| proteasome (prosome, macropain) subunit, alpha type, 2, isoform CRA_a [Homo sapiens] 99.57 1.00E-135 sp|Q3T0Y5|PSA2_BOVIN Proteasome subunit alpha type-2 OS=Bos taurus GN=PSMA2 PE=1 SV=3 100 2.00E-83 G9KIX5 G9KIX5_MUSPF Proteasome subunit alpha type (Fragment) OS=Mustela putorius furo PE=2 SV=1 PH1553 193 2.00E-49 COG0638 20S proteasome, alpha and beta subunits O Posttranslational modification, protein turnover, chaperones ; K02726|1|1e-135|482|ssc:100620420|20S proteasome subunit alpha 2 [EC:3.4.25.1] GO:0000209//protein polyubiquitination;GO:0009615//response to virus;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0016032//viral reproduction;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0005515//protein binding;GO:0004298//threonine-type endopeptidase activity GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0019773//proteasome core complex, alpha-subunit complex 261 tr|D6RGG3|D6RGG3_HUMAN Collagen alpha-1(XII) chain OS=Homo sapiens GN=COL12A1 PE=1 SV=1 381953 MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGTLLPL 5174 23.7 1 294 294 57 57 2.116 2.216 2.322 190 191 188 * * - 2.218 0.103014562 tr|D6RGG3|D6RGG3_HUMAN 99.88 0 gi|119569133|gb|EAW48748.1| collagen, type XII, alpha 1, isoform CRA_a [Homo sapiens] 99.38 0 sp|Q99715|COCA1_HUMAN Collagen alpha-1(XII) chain OS=Homo sapiens GN=COL12A1 PE=1 SV=2 100 0 D6RGG3 D6RGG3_HUMAN Collagen alpha-1(XII) chain OS=Homo sapiens GN=COL12A1 PE=4 SV=1 - - - - - - - K08132|1|0.0|5563|hsa:1303|collagen, type XII, alpha GO:0001501//skeletal system development;GO:0007155//cell adhesion;GO:0030199//collagen fibril organization GO:0030020//extracellular matrix structural constituent conferring tensile strength GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005595//collagen type XII 262 tr|A0A087WWU8|A0A087WWU8_HUMAN Tropomyosin alpha-3 chain OS=Homo sapiens GN=TPM3 PE=1 SV=1 32412 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM 1245 24.7 3 89 28 6 4 0.553 0.623 0.704 12 13 13 * * - 0.626666667 0.075566748 tr|A0A087WWU8|A0A087WWU8_HUMAN 100 3.00E-08 gi|21751375|dbj|BAC03956.1| unnamed protein product [Homo sapiens] 91.13 2.00E-83 sp|Q63610|TPM3_RAT Tropomyosin alpha-3 chain OS=Rattus norvegicus GN=Tpm3 PE=1 SV=2 100 9.00E-08 Q8NAG3 Q8NAG3_HUMAN Uncharacterized protein OS=Homo sapiens GN=TPM3 PE=2 SV=1 - - - - - - - K09290|1|4e-84|310|ssc:414388|tropomyosin 3 GO:0007420//brain development;GO:0030049//muscle filament sliding;GO:0006937//regulation of muscle contraction - GO:0005829//cytosol;GO:0030863//cortical cytoskeleton;GO:0002102//podosome;GO:0001725//stress fiber;GO:0005862//muscle thin filament tropomyosin;GO:0032154//cleavage furrow;GO:0031941//filamentous actin;GO:0030426//growth cone 263 tr|B4DJ30|B4DJ30_HUMAN cDNA FLJ61290, highly similar to Neutral alpha-glucosidase AB OS=Homo sapiens PE=2 SV=1 122057 MARALCRLPRRGLWLLLAHHLFMTTACQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSWASLVLAFLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPYRALLDSLQLGPDSLTVHLIHEVTKVLLVLELQGLQKNMTRFRIDELEPRRPRYRVPDVLVADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEHQRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYGPMSVGLDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVPVLLAHNPHRDLGIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDSGYRVHEELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVWNDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIWIERVVIIGAGKPAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASDWSIHLR 204 7.2 1 11 11 6 6 1.011 0.995 0.939 8 8 8 - - - 0.981666667 0.037806525 tr|B4DJ30|B4DJ30_HUMAN 100 0 gi|194381476|dbj|BAG58692.1| unnamed protein product [Homo sapiens] 99.68 0 sp|Q14697|GANAB_HUMAN Neutral alpha-glucosidase AB OS=Homo sapiens GN=GANAB PE=1 SV=3 100 0 B4DJ30 B4DJ30_HUMAN cDNA FLJ61290, highly similar to Neutral alpha-glucosidase AB OS=Homo sapiens PE=2 SV=1 SPAC1002.03c 675 0 COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases G Carbohydrate transport and metabolism ; K05546|1|0.0|1899|hsa:23193|alpha 1,3-glucosidase [EC:3.2.1.84] GO:0018279//protein N-linked glycosylation via asparagine;GO:0006457//protein folding;GO:0043687//post-translational protein modification GO:0033919//glucan 1,3-alpha-glucosidase activity;GO:0030246//carbohydrate binding GO:0042470//melanosome;GO:0005788//endoplasmic reticulum lumen;GO:0017177//glucosidase II complex;GO:0005794//Golgi apparatus 264 tr|B4DNR3|B4DNR3_HUMAN cDNA FLJ52710, highly similar to Abhydrolase domain-containing protein 14B OS=Homo sapiens PE=2 SV=1 22028 MAASVEQREGTIQVQGQALFFREALPGSGQARFSVLLLHGIRFSSETWQNLGTLHRLAQAGYRAVAIDLPGLGHSKEAAAPAPIGELAPGSFLAAVVDALELGPPVVPVAPICTDKINAANYASVKTPALIVYGDQDPMGQTSFEHLKQLPNHRVLIMKGAGHPCYLDKPEEWHTGLLDFLQGLQ 200 12.4 2 10 10 2 2 1.07 1.265 0.945 7 7 7 - * - 1.093333333 0.161270993 tr|B4DNR3|B4DNR3_HUMAN 100 9.00E-104 gi|194388714|dbj|BAG60325.1| unnamed protein product [Homo sapiens] 88.1 1.00E-100 sp|Q96IU4|ABHEB_HUMAN Abhydrolase domain-containing protein 14B OS=Homo sapiens GN=ABHD14B PE=1 SV=1 100 3.00E-103 B4DNR3 B4DNR3_HUMAN Abhydrolase domain-containing protein 14B OS=Homo sapiens GN=ABHD14B PE=2 SV=1 SSO2262 73.6 2.00E-13 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) R General function prediction only ; K13706|1|1e-100|364|hsa:84836|abhydrolase domain-containing protein 14 - GO:0016787//hydrolase activity GO:0005730//nucleolus;GO:0005737//cytoplasm 265 tr|Q32Q12|Q32Q12_HUMAN Nucleoside diphosphate kinase OS=Homo sapiens GN=NME1-NME2 PE=1 SV=1 39903 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRTMANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 461 36.6 - 50 50 10 10 0.84 0.62 0.747 26 26 26 - * - 0.735666667 0.110437011 tr|Q32Q12|Q32Q12_HUMAN 100 2.00E-84 gi|1421609|pdb|1NUE|A Chain A, X-ray Structure Of Nm23 Human Nucleoside Diphosphate Kinase B Complexed With Gdp At 2 Angstroms Resolution >gi|1421610|pdb|1NUE|B Chain B, X-ray Structure Of Nm23 Human Nucleoside Diphosphate Kinase B Complexed With Gdp At 2 Angstroms Resolution >gi|1421611|pdb|1NUE|C Chain C, X-ray Structure Of Nm23 Human Nucleoside Diphosphate Kinase B Complexed With Gdp At 2 Angstroms Resolution >gi|1421612|pdb|1NUE|D Chain D, X-ray Structure Of Nm23 Human Nucleoside Diphosphate Kinase B Complexed With Gdp At 2 Angstroms Resolution >gi|1421613|pdb|1NUE|E Chain E, X-ray Structure Of Nm23 Human Nucleoside Diphosphate Kinase B Complexed With Gdp At 2 Angstroms Resolution >gi|1421614|pdb|1NUE|F Chain F, X-ray Structure Of Nm23 Human Nucleoside Diphosphate Kinase B Complexed With Gdp At 2 Angstroms Resolution >gi|206581866|pdb|3BBB|A Chain A, Crystal Structure Of The Nm23-H2 Transcription Factor Complex With Dinucleotide D(Ag) >gi|206581867|pdb|3BBB|B Chain B, Crystal Structure Of The Nm23-H2 Transcription Factor Complex With Dinucleotide D(Ag) >gi|206581868|pdb|3BBB|C Chain C, Crystal Structure Of The Nm23-H2 Transcription Factor Complex With Dinucleotide D(Ag) >gi|206581869|pdb|3BBB|D Chain D, Crystal Structure Of The Nm23-H2 Transcription Factor Complex With Dinucleotide D(Ag) >gi|206581870|pdb|3BBB|E Chain E, Crystal Structure Of The Nm23-H2 Transcription Factor Complex With Dinucleotide D(Ag) >gi|206581871|pdb|3BBB|F Chain F, Crystal Structure Of The Nm23-H2 Transcription Factor Complex With Dinucleotide D(Ag) >gi|206581878|pdb|3BBF|A Chain A, Crystal Structure Of The Nm23-H2 Transcription Factor Complex With Gdp >gi|206581879|pdb|3BBF|B Chain B, Crystal Structure Of The Nm23-H2 Transcription Factor Complex With Gdp >gi|206581880|pdb|3BBF|C Chain C, Crystal Structure Of The Nm23-H2 Transcription Factor Complex With Gdp >gi|206581881|pdb|3BBF|D Chain D, Crystal Structure Of The Nm23-H2 Transcription Factor Complex With Gdp >gi|206581882|pdb|3BBF|E Chain E, Crystal Structure Of The Nm23-H2 Transcription Factor Complex With Gdp >gi|206581883|pdb|3BBF|F Chain F, Crystal Structure Of The Nm23-H2 Transcription Factor Complex With Gdp 100 5.00E-86 sp|P22392|NDKB_HUMAN Nucleoside diphosphate kinase B OS=Homo sapiens GN=NME2 PE=1 SV=1 100 3.00E-75 E7ERL0 E7ERL0_HUMAN Nucleoside diphosphate kinase A OS=Homo sapiens GN=NME1 PE=3 SV=1 YKL067w 203 3.00E-52 COG0105 Nucleoside diphosphate kinase F Nucleotide transport and metabolism ; K00940|1|1e-157|555|mcc:707717|nucleoside-diphosphate kinase [EC:2.7.4.6] GO:0006228//UTP biosynthetic process;GO:0006183//GTP biosynthetic process;GO:0006241//CTP biosynthetic process GO:0004550//nucleoside diphosphate kinase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding GO:0005737//cytoplasm 266 tr|B2MUX6|B2MUX6_HUMAN Insulin-like growth factor 2 OS=Homo sapiens GN=IGF2 PE=3 SV=1 8592 MVAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSPGIVEECCFRSCDLALLETYCATPAKSE 130 23.2 3 6 6 1 1 2.458 2.274 3.026 3 4 4 - * * 2.586 0.392 tr|B2MUX6|B2MUX6_HUMAN 100 9.00E-25 gi|186926672|gb|ACC95538.1| insulin-like growth factor 2 [Homo sapiens] 95.65 1.00E-25 sp|P01344|IGF2_HUMAN Insulin-like growth factor II OS=Homo sapiens GN=IGF2 PE=1 SV=1 100 4.00E-24 B2MUX6 B2MUX6_HUMAN Insulin-like growth factor 2 OS=Homo sapiens GN=IGF2 PE=3 SV=1 - - - - - - - K13769|1|9e-26|115|hsa:3481|insulin-like growth factor 2 GO:0042104//positive regulation of activated T cell proliferation;GO:0001501//skeletal system development;GO:0031667//response to nutrient levels;GO:2000467//positive regulation of glycogen (starch) synthase activity;GO:0009314//response to radiation;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0090031//positive regulation of steroid hormone biosynthetic process;GO:0043410//positive regulation of MAPK cascade;GO:0051781//positive regulation of cell division;GO:0006349//regulation of gene expression by genetic imprinting;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001649//osteoblast differentiation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0038028//insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0051146//striated muscle cell differentiation;GO:0051897//positive regulation of protein kinase B signaling cascade;GO:0032355//response to estradiol stimulus;GO:2000273//positive regulation of receptor activity;GO:0035094//response to nicotine;GO:0042493//response to drug;GO:0045840//positive regulation of mitosis;GO:0031017//exocrine pancreas development;GO:0009887//organ morphogenesis GO:0043539//protein serine/threonine kinase activator activity;GO:0008083//growth factor activity;GO:0005159//insulin-like growth factor receptor binding;GO:0030546//receptor activator activity;GO:0005158//insulin receptor binding;GO:0005179//hormone activity GO:0005615//extracellular space 267 sp|Q8NBJ4|GOLM1_HUMAN Golgi membrane protein 1 OS=Homo sapiens GN=GOLM1 PE=1 SV=1 >tr|B3KNK9|B3KNK9_HUMAN Epididymis luminal protein 46 OS=Homo sapiens GN=HEL46 PE=2 SV=1 52474 MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREKRNHTL 149 5.5 - 7 7 3 3 1.252 1.406 1.417 5 4 5 - * - 1.358333333 0.092251468 sp|Q8NBJ4|GOLM1_HUMAN 100 0 gi|29550838|ref|NP_057632.2| Golgi membrane protein 1 [Homo sapiens] >gi|29550850|ref|NP_808800.1| Golgi membrane protein 1 [Homo sapiens] >gi|51316027|sp|Q8NBJ4.1|GOLM1_HUMAN RecName: Full=Golgi membrane protein 1; AltName: Full=Golgi membrane protein GP73; AltName: Full=Golgi phosphoprotein 2 >gi|37182308|gb|AAQ88956.1| GOLPH2 [Homo sapiens] >gi|119583109|gb|EAW62705.1| golgi phosphoprotein 2, isoform CRA_a [Homo sapiens] >gi|119583110|gb|EAW62706.1| golgi phosphoprotein 2, isoform CRA_a [Homo sapiens] 100 0 sp|Q8NBJ4|GOLM1_HUMAN Golgi membrane protein 1 OS=Homo sapiens GN=GOLM1 PE=1 SV=1 100 0 B3KNK9 B3KNK9_HUMAN Golgi phosphoprotein 2, isoform CRA_a OS=Homo sapiens GN=GOLPH2 PE=2 SV=1 - - - - - - - - - GO:0005515//protein binding GO:0005887//integral to plasma membrane;GO:0005794//Golgi apparatus 268 tr|A0A024RDE8|A0A024RDE8_HUMAN PDZ and LIM domain 5, isoform CRA_c OS=Homo sapiens GN=PDLIM5 PE=4 SV=1 76083 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITSPAVSKVTSTNNMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPLFAASGLHANANLSADQSPSALSAGKTAVNVPRQPTVTSVCSETSQELAEGQRRGSQGDSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTTAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF 126 5.4 2 8 8 3 3 0.502 0.679 0.496 6 6 6 - - * 0.559 0.103966341 tr|A0A024RDE8|A0A024RDE8_HUMAN 100 5.00E-164 gi|374093203|ref|NP_001243354.1| PDZ and LIM domain protein 5 isoform c [Homo sapiens] >gi|119626463|gb|EAX06058.1| PDZ and LIM domain 5, isoform CRA_e [Homo sapiens] 99.83 0 sp|Q96HC4|PDLI5_HUMAN PDZ and LIM domain protein 5 OS=Homo sapiens GN=PDLIM5 PE=1 SV=5 100 3.00E-49 B7Z8X5 B7Z8X5_HUMAN cDNA FLJ61541, highly similar to Homo sapiens PDZ and LIM domain 5 (PDLIM5), transcript variant 2, mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K05760|1|1e-39|165|isc:IscW_ISCW009899|paxillin GO:0061001//regulation of dendritic spine morphogenesis;GO:0051963//regulation of synapse assembly GO:0005080//protein kinase C binding;GO:0047485//protein N-terminus binding;GO:0008270//zinc ion binding;GO:0003779//actin binding;GO:0042805//actinin binding GO:0005829//cytosol;GO:0030054//cell junction;GO:0030018//Z disc;GO:0015629//actin cytoskeleton;GO:0045211//postsynaptic membrane;GO:0014069//postsynaptic density;GO:0005886//plasma membrane 269 tr|B4DV28|B4DV28_HUMAN cDNA FLJ54170, highly similar to Cytosolic nonspecific dipeptidase OS=Homo sapiens PE=2 SV=1 63067 MAALTTLFKYIDENQDRYIKKLAKWVAIQSVSAWPEKRGEIRRMMEVAAADVKQLGGSVELVDIGKQKLPDGSEIPLPPILLGRLGSDPQKKTVCIYGHLDVQPAALERDGKLYGRGSTDDKGPVAGWINALEAYQKTGQEIPVNVRFCLEGMEESGSEGLDELIFARKDTFFKDVDYVCISDNYWLGKKKPCITYGLRGICYFFIEVECSNKDLHSGVYGGSVHEAMTDLILLMGSLVDKRGNILIPGINEAVAAVTEEEHKLYDDIDFDIEEFAKDVGAQILLHSHKKDILMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVVGKFSIRLVPNMTPEVVGEQVTSYLTKKFAELRSPNEFKVYMGHGGKPWVSDFSHPHYLAGRRAMKTVFGVEPDLTREGGSIPVTLTFQEATGKNVMLLPVGSADDGAHSQNEKLNRYNYIEGTKMLAAYLYEVSQLKD 101 14.9 1 8 8 4 4 1.435 1.318 1.251 5 5 5 * - - 1.334666667 0.093125364 tr|B4DV28|B4DV28_HUMAN 100 4.00E-177 gi|7022407|dbj|BAA91587.1| unnamed protein product [Homo sapiens] 97.47 0 sp|Q96KP4|CNDP2_HUMAN Cytosolic non-specific dipeptidase OS=Homo sapiens GN=CNDP2 PE=1 SV=2 100 1.00E-176 Q9NW02 Q9NW02_HUMAN cDNA FLJ10400 fis, clone NT2RM4000395 OS=Homo sapiens PE=2 SV=1 SPBC1198.08 494 2.00E-139 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases E Amino acid transport and metabolism ; K08660|1|0.0|884|ptr:455473|cytosolic nonspecific dipeptidase [EC:3.4.13.18] GO:0006805//xenobiotic metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006508//proteolysis;GO:0006750//glutathione biosynthetic process;GO:0000096//sulfur amino acid metabolic process GO:0046872//metal ion binding;GO:0004180//carboxypeptidase activity;GO:0016805//dipeptidase activity;GO:0008237//metallopeptidase activity;GO:0034701//tripeptidase activity GO:0005829//cytosol 270 sp|P43251|BTD_HUMAN Biotinidase OS=Homo sapiens GN=BTD PE=1 SV=2 68090 MAHAHIQGGRRAKSRFVVCIMSGARSKLALFLCGCYVVALGAHTGEESVADHHEAEYYVAAVYEHPSILSLNPLALISRQEALELMNQNLDIYEQQVMTAAQKDVQIIVFPEDGIHGFNFTRTSIYPFLDFMPSPQVVRWNPCLEPHRFNDTEVLQRLSCMAIRGDMFLVANLGTKEPCHSSDPRCPKDGRYQFNTNVVFSNNGTLVDRYRKHNLYFEAAFDVPLKVDLITFDTPFAGRFGIFTCFDILFFDPAIRVLRDYKVKHVVYPTAWMNQLPLLAAIEIQKAFAVAFGINVLAANVHHPVLGMTGSGIHTPLESFWYHDMENPKSHLIIAQVAKNPVGLIGAENATGETDPSHSKFLKILSGDPYCEKDAQEVHCDEATKWNVNAPPTFHSEMMYDNFTLVPVWGKEGYLHVCSNGLCCYLLYERPTLSKELYALGVFDGLHTVHGTYYIQVCALVRCGGLGFDTCGQEITEATGIFEFHLWGNFSTSYIFPLFLTSGMTLEVPDQLGWENDHYFLRKSRLSSGLVTAALYGRLYERD 115 4.1 - 5 5 2 2 1.134 0.924 0.974 3 3 3 - - - 1.010666667 0.109696551 sp|P43251|BTD_HUMAN 100 0 gi|4557373|ref|NP_000051.1| biotinidase precursor [Homo sapiens] >gi|226693503|sp|P43251.2|BTD_HUMAN RecName: Full=Biotinidase; Short=Biotinase; Flags: Precursor >gi|468824|gb|AAC04318.1| biotinidase [Homo sapiens] >gi|2674075|gb|AAC21679.1| biotinidase [Homo sapiens] >gi|15082373|gb|AAH12099.1| Biotinidase [Homo sapiens] >gi|119584658|gb|EAW64254.1| biotinidase, isoform CRA_a [Homo sapiens] 100 0 sp|P43251|BTD_HUMAN Biotinidase OS=Homo sapiens GN=BTD PE=1 SV=2 100 7.00E-25 C9J387 C9J387_HUMAN Biotinidase (Fragment) OS=Homo sapiens GN=BTD PE=4 SV=1 - - - - - - - K01435|1|0.0|1138|hsa:686|biotinidase [EC:3.5.1.12] GO:0007417//central nervous system development;GO:0008544//epidermis development;GO:0006807//nitrogen compound metabolic process GO:0004075//biotin carboxylase activity;GO:0047708//biotinidase activity GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0045177//apical part of cell;GO:0043204//perikaryon 271 tr|A0A024R498|A0A024R498_HUMAN Serpin peptidase inhibitor, clade E (Nexin, plasminogen activator inhibitor type 1), member 2, isoform CRA_b OS=Homo sapiens GN=SERPINE2 PE=3 SV=1 53326 MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 1945 36.8 2 120 120 15 15 1.15 0.776 1.127 76 80 79 - * - 1.017666667 0.209605184 tr|A0A024R498|A0A024R498_HUMAN 100 0 gi|332815503|ref|XP_001167141.2| PREDICTED: glia-derived nexin isoform 3 [Pan troglodytes] >gi|397495795|ref|XP_003818731.1| PREDICTED: glia-derived nexin isoform 1 [Pan paniscus] 99.5 0 sp|P07093|GDN_HUMAN Glia-derived nexin OS=Homo sapiens GN=SERPINE2 PE=1 SV=1 100 0 H2QJI9 H2QJI9_PANTR Uncharacterized protein (Fragment) OS=Pan troglodytes GN=ENSG00000135919 PE=3 SV=1 all0778 182 1.00E-45 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K03982|1|3e-83|309|hsa:5054|plasminogen activator inhibitor-1 GO:0045879//negative regulation of smoothened signaling pathway;GO:0030334//regulation of cell migration;GO:0061108//seminal vesicle epithelium development;GO:0014067//negative regulation of phosphatidylinositol 3-kinase cascade;GO:0033363//secretory granule organization;GO:0021683//cerebellar granular layer morphogenesis;GO:0042177//negative regulation of protein catabolic process;GO:0048505//regulation of timing of cell differentiation;GO:0010544//negative regulation of platelet activation;GO:0045861//negative regulation of proteolysis;GO:0009314//response to radiation;GO:0061110//dense core granule biogenesis;GO:0050974//detection of mechanical stimulus involved in sensory perception;GO:0010757//negative regulation of plasminogen activation;GO:0032940//secretion by cell;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0010951//negative regulation of endopeptidase activity;GO:0007566//embryo implantation;GO:0008285//negative regulation of cell proliferation;GO:0042628//mating plug formation;GO:0060291//long-term synaptic potentiation;GO:0010976//positive regulation of neuron projection development;GO:0048711//positive regulation of astrocyte differentiation;GO:0030308//negative regulation of cell growth;GO:0010766//negative regulation of sodium ion transport;GO:0090331//negative regulation of platelet aggregation;GO:0060384//innervation GO:0008201//heparin binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005102//receptor binding GO:0031232//extrinsic to external side of plasma membrane;GO:0031594//neuromuscular junction;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0031091//platelet alpha granule;GO:0043025//neuronal cell body;GO:0031012//extracellular matrix 272 tr|B3KQT2|B3KQT2_HUMAN Protein disulfide-isomerase OS=Homo sapiens PE=2 SV=1 70782 MTLWILPKFKAVDFSPSLAAYTHTWLLPRFLEILIQCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENIFGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDSISYLQREATNPPVIQEEKPKKKKKAQEDL 852 32.6 2 58 58 14 14 0.898 0.721 0.916 31 32 30 - - - 0.845 0.10776363 tr|B3KQT2|B3KQT2_HUMAN 100 0 gi|193786821|dbj|BAG52144.1| unnamed protein product [Homo sapiens] 99.78 0 sp|P30101|PDIA3_HUMAN Protein disulfide-isomerase A3 OS=Homo sapiens GN=PDIA3 PE=1 SV=4 100 0 B3KQT2 B3KQT2_HUMAN cDNA PSEC0148 fis, clone PLACE1007202, highly similar to Protein disulfide-isomerase A3 (EC 5.3.4.1) OS=Homo sapiens PE=2 SV=1 SPAC1F5.02 249 7.00E-66 COG0526 Thiol-disulfide isomerase and thioredoxins OC Posttranslational modification, protein turnover, chaperones ; Energy production and conversion ; K08056|1|0.0|987|ptr:742723|protein disulfide isomerase family A, member 3 [EC:5.3.4.1] GO:0006457//protein folding;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0045454//cell redox homeostasis;GO:0043065//positive regulation of apoptotic process;GO:0007165//signal transduction;GO:0006662//glycerol ether metabolic process;GO:0043687//post-translational protein modification;GO:0006606//protein import into nucleus;GO:0006621//protein retention in ER lumen;GO:0018279//protein N-linked glycosylation via asparagine GO:0015035//protein disulfide oxidoreductase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0004629//phospholipase C activity;GO:0005515//protein binding;GO:0003756//protein disulfide isomerase activity;GO:0009055//electron carrier activity GO:0005788//endoplasmic reticulum lumen;GO:0042470//melanosome 273 sp|P26038|MOES_HUMAN Moesin OS=Homo sapiens GN=MSN PE=1 SV=3 >tr|V9HWC0|V9HWC0_HUMAN Epididymis luminal protein 70 OS=Homo sapiens GN=HEL70 PE=2 SV=1 87057 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM 967 22.4 - 82 34 13 7 0.794 0.786 0.793 28 29 28 * * * 0.791 0.004358899 sp|P26038|MOES_HUMAN 100 0 gi|355704876|gb|EHH30801.1| Membrane-organizing extension spike protein, partial [Macaca mulatta] >gi|355757423|gb|EHH60948.1| Membrane-organizing extension spike protein, partial [Macaca fascicularis] 100 0 sp|P26038|MOES_HUMAN Moesin OS=Homo sapiens GN=MSN PE=1 SV=3 100 0 G1QHZ4 G1QHZ4_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=MSN PE=4 SV=1 - - - - - - - K05763|1|0.0|1039|mcc:711712|moesin GO:0022614//membrane to membrane docking;GO:2000401//regulation of lymphocyte migration;GO:0007159//leukocyte cell-cell adhesion GO:0005102//receptor binding;GO:0003779//actin binding;GO:0050839//cell adhesion molecule binding;GO:0019901//protein kinase binding;GO:0005200//structural constituent of cytoskeleton GO:0019898//extrinsic to membrane;GO:0009898//internal side of plasma membrane;GO:0031527//filopodium membrane;GO:0005856//cytoskeleton;GO:0005730//nucleolus;GO:0009986//cell surface;GO:0001931//uropod;GO:0005925//focal adhesion;GO:0030667//secretory granule membrane;GO:0016324//apical plasma membrane;GO:0031528//microvillus membrane 274 sp|P01023|A2MG_HUMAN Alpha-2-macroglobulin OS=Homo sapiens GN=A2M PE=1 SV=3 191992 MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDNEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA 776 8.5 - 61 34 10 8 0.584 0.647 0.7 19 18 18 * * - 0.643666667 0.058071795 sp|P01023|A2MG_HUMAN 100 0 gi|308153640|sp|P01023.3|A2MG_HUMAN RecName: Full=Alpha-2-macroglobulin; Short=Alpha-2-M; AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; Flags: Precursor 100 0 sp|P01023|A2MG_HUMAN Alpha-2-macroglobulin OS=Homo sapiens GN=A2M PE=1 SV=3 100 0 H0YGH4 H0YGH4_HUMAN Alpha-2-macroglobulin OS=Homo sapiens GN=A2M PE=4 SV=1 TM0984 74.7 1.00E-12 COG2373 Large extracellular alpha-helical protein R General function prediction only ; K03910|1|0.0|2947|hsa:2|alpha-2-macroglobulin GO:0030168//platelet activation;GO:0001869//negative regulation of complement activation, lectin pathway;GO:0010951//negative regulation of endopeptidase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007597//blood coagulation, intrinsic pathway;GO:0002576//platelet degranulation GO:0019966//interleukin-1 binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0043120//tumor necrosis factor binding;GO:0019959//interleukin-8 binding;GO:0019899//enzyme binding GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005829//cytosol 275 tr|A8K7Q1|A8K7Q1_HUMAN cDNA FLJ77770, highly similar to Homo sapiens nucleobindin 1 (NUCB1), mRNA OS=Homo sapiens PE=2 SV=1 62976 MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKSGKLSRELDFVSHHVRTKLDELKRQEVSRLRMLLKAKMDAEQDPNVQVDHLNLLKQFEHLDPQNQHTFEARDLELLIQTATRDLAQYDAAHHEEFKRYEMLKEHERRRYLESLGEEQRKEAERKLEEQQRRHREHPKVNVPGSQAQLKEVWEELDGLDPNRFNPKTFFILHDINSDGVLDEQELEALFTKELEKVHDPKNEEDDMREMEEERLRMWEHVMKNVDTNQDRLVTLEEFLASTQRKEFGDTGEGWETVEMHPAYTEEELRRFEEELAAREAELNAKAQRLSQETEALGRSQGRLEAQKRELQQAVLHMEQRKQQQQQQQGHKAPAAHPEGQLKFHPDTDDVPVPAPAGDQKEVDTSEKKLLERLPEVEVPQHL 826 31.5 2 46 46 12 12 0.966 1.056 1.244 29 29 25 - - * 1.088666667 0.141849686 tr|A8K7Q1|A8K7Q1_HUMAN 100 0 gi|158257564|dbj|BAF84755.1| unnamed protein product [Homo sapiens] 99.57 0 sp|Q02818|NUCB1_HUMAN Nucleobindin-1 OS=Homo sapiens GN=NUCB1 PE=1 SV=4 100 5.00E-35 B3KUR6 B3KUR6_HUMAN cDNA FLJ40471 fis, clone TESTI2042508, highly similar to Nucleobindin-1 OS=Homo sapiens PE=2 SV=1 - - - - - - - K12385|1|9e-59|228|isc:IscW_ISCW020300|Niemann-Pick C1 protein - GO:0003677//DNA binding;GO:0005509//calcium ion binding GO:0015630//microtubule cytoskeleton;GO:0016020//membrane;GO:0005615//extracellular space;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus 276 tr|B4E0K9|B4E0K9_HUMAN Alpha-mannosidase OS=Homo sapiens PE=2 SV=1 115460 MLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVATAQGRYYRTNHTVMTMGSDFQYENANMWFKNLDKLIRLVNAQQAKGSSVHVLYSTPACYLWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVGLAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNALARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDPNGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQLREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG 100 4.3 3 5 5 3 3 1.021 1.362 1.087 4 4 4 - - - 1.156666667 0.180859983 tr|B4E0K9|B4E0K9_HUMAN 100 0 gi|2209015|gb|AAC51362.1| lysosomal alpha-mannosidase [Homo sapiens] 100 0 sp|O00754|MA2B1_HUMAN Lysosomal alpha-mannosidase OS=Homo sapiens GN=MAN2B1 PE=1 SV=3 100 0 B4E0K9 B4E0K9_HUMAN Lysosomal alpha-mannosidase B peptide OS=Homo sapiens GN=MAN2B1 PE=2 SV=1 TM1851 53.5 2.00E-06 COG0383 Alpha-mannosidase G Carbohydrate transport and metabolism ; K12311|1|0.0|1928|hsa:4125|lysosomal alpha-mannosidase [EC:3.2.1.24] GO:0006013//mannose metabolic process;GO:0006517//protein deglycosylation GO:0004559//alpha-mannosidase activity;GO:0030246//carbohydrate binding;GO:0008270//zinc ion binding GO:0005764//lysosome 277 tr|C9JMH6|C9JMH6_HUMAN Alpha-2-antiplasmin (Fragment) OS=Homo sapiens GN=SERPINF2 PE=3 SV=1 31190 MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQTALKSPPGVCSRDPTPEQTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSF 208 14.5 1 11 11 3 3 0.845 0.793 0.837 8 7 7 * - - 0.825 0.028 tr|C9JMH6|C9JMH6_HUMAN 100 4.00E-133 gi|178751|gb|AAA35543.1| alpha-2-antiplasmin precursor, partial [Homo sapiens] 100 1.00E-135 sp|P08697|A2AP_HUMAN Alpha-2-antiplasmin OS=Homo sapiens GN=SERPINF2 PE=1 SV=3 100 1.00E-57 C9JY78 C9JY78_HUMAN Alpha-2-antiplasmin (Fragment) OS=Homo sapiens GN=SERPINF2 PE=4 SV=1 all0778 88.6 1.00E-17 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K03983|1|1e-135|482|hsa:5345|alpha-2-antiplasmin GO:0002034//regulation of blood vessel size by renin-angiotensin;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0030199//collagen fibril organization;GO:0030162//regulation of proteolysis;GO:0030168//platelet activation;GO:0051918//negative regulation of fibrinolysis;GO:0006953//acute-phase response;GO:0010757//negative regulation of plasminogen activation;GO:0045597//positive regulation of cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010033//response to organic substance;GO:0051496//positive regulation of stress fiber assembly;GO:0002576//platelet degranulation;GO:0010951//negative regulation of endopeptidase activity;GO:0048514//blood vessel morphogenesis;GO:0046330//positive regulation of JNK cascade;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin;GO:0071636//positive regulation of transforming growth factor beta production;GO:0032967//positive regulation of collagen biosynthetic process GO:0042803//protein homodimerization activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0002020//protease binding;GO:0043499//eukaryotic cell surface binding GO:0005577//fibrinogen complex;GO:0031093//platelet alpha granule lumen 278 tr|B4DY09|B4DY09_HUMAN Interleukin enhancer-binding factor 2 OS=Homo sapiens GN=ILF2 PE=1 SV=1 44533 MAFPRVKPAPDETSFSEALLKRNQDLAPNSAEQASILSLVTKINNVIDNLIVAPGTFEVQIEEVRQVGSYKKGTMTTGHNVADLVVILKILPTLEAVAALGNKVVESLRAQDPSEVLTMLTNETGFEISSSDATVKILITTVPPNLRKLDPELHLDIKVLQSALAAIRHARWFEENASQSTVKVLIRLLKDLRIRFPGFEPLTPWILDLLGHYAVMNNPTRQPLALNVAYRRCLQILAAGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQTLVRILSHGGFRKILGQEGDASYLASEISTWDGVIVTPSEKAYEKPPEKKEGEEEEENTEEPPQGEEEESMETQE 133 14.5 2 5 5 4 4 1.12 1.136 1.482 4 4 4 - - * 1.246 0.204538505 tr|B4DY09|B4DY09_HUMAN 100 0 gi|440892888|gb|ELR45880.1| Interleukin enhancer-binding factor 2, partial [Bos grunniens mutus] 100 0 sp|Q5RFJ1|ILF2_PONAB Interleukin enhancer-binding factor 2 OS=Pongo abelii GN=ILF2 PE=2 SV=1 100 2.00E-96 G9K5P7 G9K5P7_MUSPF Interleukin enhancer binding factor 2, 45kDa (Fragment) OS=Mustela putorius furo PE=2 SV=1 - - - - - - - K13089|1|0.0|645|pon:100172468|interleukin enhancer-binding factor 2 GO:0006955//immune response;GO:0045893//positive regulation of transcription, DNA-dependent GO:0003677//DNA binding;GO:0003725//double-stranded RNA binding;GO:0005524//ATP binding;GO:0016740//transferase activity;GO:0005515//protein binding GO:0005730//nucleolus;GO:0030529//ribonucleoprotein complex;GO:0005737//cytoplasm 279 tr|K7ELW0|K7ELW0_HUMAN Protein DJ-1 OS=Homo sapiens GN=PARK7 PE=1 SV=1 23241 MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGTSFEFALAIVEALNGKEVAAQVKAPLVLKD 227 22.5 1 13 13 4 4 1.009 0.941 0.966 11 11 11 - - - 0.972 0.034394767 tr|K7ELW0|K7ELW0_HUMAN 100 3.00E-09 gi|66866411|gb|AAY57853.1| DJ-1 protein, partial [Sus scrofa] 89.42 1.00E-89 sp|Q99497|PARK7_HUMAN Protein DJ-1 OS=Homo sapiens GN=PARK7 PE=1 SV=2 93.83 5.00E-38 G9KF71 G9KF71_MUSPF Parkinson disease 7 (Fragment) OS=Mustela putorius furo PE=2 SV=1 VC2308 100 1.00E-21 COG0693 Putative intracellular protease/amidase R General function prediction only ; K05687|1|1e-89|328|hsa:11315|protein DJ-1 GO:0007338//single fertilization;GO:2000277//positive regulation of oxidative phosphorylation uncoupler activity;GO:0032091//negative regulation of protein binding;GO:0051583//dopamine uptake involved in synaptic transmission;GO:0060081//membrane hyperpolarization;GO:0070301//cellular response to hydrogen peroxide;GO:0060765//regulation of androgen receptor signaling pathway;GO:0042743//hydrogen peroxide metabolic process;GO:0050821//protein stabilization;GO:0051899//membrane depolarization;GO:0042493//response to drug;GO:0006914//autophagy;GO:0007005//mitochondrion organization;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0006508//proteolysis;GO:0043524//negative regulation of neuron apoptotic process;GO:0050727//regulation of inflammatory response;GO:0008344//adult locomotory behavior GO:0051920//peroxiredoxin activity;GO:0004601//peroxidase activity;GO:0008233//peptidase activity;GO:0042803//protein homodimerization activity;GO:0003729//mRNA binding GO:0005829//cytosol;GO:0030424//axon;GO:0005634//nucleus;GO:0005739//mitochondrion 280 tr|A0A087X020|A0A087X020_HUMAN Ribosome maturation protein SBDS OS=Homo sapiens GN=SBDS PE=1 SV=1 39474 MSIFTPTNQIRLTNVAVVRMKRAGKRFEIACYKNKVVGWRSAWEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKTNKSTKQQALEVIKQLKEKMKIERAHMRLRFILPVNEGKKLKEKLKPLIKVIESEDYGQQLEIVCLIDPGCFREIDELIKKETKGKGSLEVLNLKDVEEGDEKFE 73 21.6 1 6 6 5 5 0.837 0.972 1.021 3 3 3 - - - 0.943333333 0.095290783 tr|A0A087X020|A0A087X020_HUMAN 99.2 3.00E-133 gi|28416940|ref|NP_057122.2| ribosome maturation protein SBDS [Homo sapiens] >gi|197102836|ref|NP_001125618.1| ribosome maturation protein SBDS [Pongo abelii] >gi|28380824|sp|Q9Y3A5.4|SBDS_HUMAN RecName: Full=Ribosome maturation protein SBDS; AltName: Full=Shwachman-Bodian-Diamond syndrome protein >gi|75041953|sp|Q5RAZ2.1|SBDS_PONAB RecName: Full=Ribosome maturation protein SBDS; AltName: Full=Shwachman-Bodian-Diamond syndrome protein homolog >gi|27802129|gb|AAN77490.1| Shwachman-Bodian-Diamond syndrome protein [Homo sapiens] >gi|41350825|gb|AAH65700.1| Shwachman-Bodian-Diamond syndrome [Homo sapiens] >gi|119628311|gb|EAX07906.1| Shwachman-Bodian-Diamond syndrome [Homo sapiens] >gi|355560587|gb|EHH17273.1| Shwachman-Bodian-Diamond syndrome protein [Macaca mulatta] >gi|355747610|gb|EHH52107.1| Shwachman-Bodian-Diamond syndrome protein [Macaca fascicularis] 99.2 3.00E-134 sp|Q9Y3A5|SBDS_HUMAN Ribosome maturation protein SBDS OS=Homo sapiens GN=SBDS PE=1 SV=4 99.2 9.00E-133 G7MP28 G7MP28_MACMU Ribosome maturation protein SBDS OS=Macaca mulatta GN=SBDS PE=2 SV=1 SPAC4F8.03 244 1.00E-64 COG1500 Predicted exosome subunit J Translation, ribosomal structure and biogenesis ; K14574|1|3e-134|477|pon:100172536|ribosome maturation protein SDO1 GO:0043148//mitotic spindle stabilization;GO:0042273//ribosomal large subunit biogenesis;GO:0001833//inner cell mass cell proliferation;GO:0030282//bone mineralization;GO:0042256//mature ribosome assembly;GO:0048539//bone marrow development;GO:0006364//rRNA processing;GO:0030595//leukocyte chemotaxis GO:0043022//ribosome binding;GO:0008017//microtubule binding;GO:0019843//rRNA binding GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0000922//spindle pole 281 tr|B4DGL0|B4DGL0_HUMAN cDNA FLJ53619, highly similar to Heat shock protein HSP 90-beta OS=Homo sapiens PE=2 SV=1 105637 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRCESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGDPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRMEEVD 888 19.7 2 39 15 13 8 1.283 0.909 1.526 10 10 10 - - * 1.239333333 0.310809159 tr|B4DGL0|B4DGL0_HUMAN 100 0 gi|194378142|dbj|BAG57821.1| unnamed protein product [Homo sapiens] 98.34 0 sp|P08238|HS90B_HUMAN Heat shock protein HSP 90-beta OS=Homo sapiens GN=HSP90AB1 PE=1 SV=4 100 0 B4DGL0 B4DGL0_HUMAN cDNA FLJ53619, highly similar to Heat shock protein HSP 90-beta OS=Homo sapiens PE=2 SV=1 SPAC926.04c 820 0 COG0326 Molecular chaperone, HSP90 family O Posttranslational modification, protein turnover, chaperones ; K04079|1|0.0|1175|hsa:3326|molecular chaperone HtpG GO:0043524//negative regulation of neuron apoptotic process;GO:0071407//cellular response to organic cyclic compound;GO:0032092//positive regulation of protein binding;GO:0007411//axon guidance;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0009651//response to salt stress;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0006986//response to unfolded protein;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0045793//positive regulation of cell size;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0001890//placenta development;GO:0006457//protein folding;GO:0033160//positive regulation of protein import into nucleus, translocation GO:0005525//GTP binding;GO:0002135//CTP binding;GO:0002134//UTP binding;GO:0051082//unfolded protein binding;GO:0017098//sulfonylurea receptor binding;GO:0032564//dATP binding;GO:0044325//ion channel binding;GO:0005524//ATP binding;GO:0030911//TPR domain binding;GO:0019901//protein kinase binding;GO:0030235//nitric-oxide synthase regulator activity GO:0009986//cell surface;GO:0031526//brush border membrane;GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0016323//basolateral plasma membrane;GO:0008180//signalosome;GO:0005739//mitochondrion;GO:0042470//melanosome;GO:0016234//inclusion body 282 tr|G3V4Y7|G3V4Y7_HUMAN Kinectin OS=Homo sapiens GN=KTN1 PE=1 SV=1 92059 MVPSCCFFRCRKQKDNRYQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE 85 4 1 3 3 2 2 --- 0.702 1.147 1 2 2 - - - 0.9245 0.314662518 tr|G3V4Y7|G3V4Y7_HUMAN 100 0 gi|118498368|ref|NP_004977.2| kinectin isoform c [Homo sapiens] >gi|409466|gb|AAB65853.1| kinectin [Homo sapiens] >gi|119601089|gb|EAW80683.1| kinectin 1 (kinesin receptor), isoform CRA_c [Homo sapiens] >gi|119601091|gb|EAW80685.1| kinectin 1 (kinesin receptor), isoform CRA_d [Homo sapiens] 91.01 0 sp|Q86UP2|KTN1_HUMAN Kinectin OS=Homo sapiens GN=KTN1 PE=1 SV=1 100 4.00E-48 G3V5P0 G3V5P0_HUMAN Kinectin (Fragment) OS=Homo sapiens GN=KTN1 PE=4 SV=1 - - - - - - - K14000|1|5e-14|80.1|bfo:BRAFLDRAFT_66351|ribosome-binding protein 1 - - GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral to plasma membrane 283 tr|A0A087WYR3|A0A087WYR3_HUMAN Tumor protein D54 OS=Homo sapiens GN=TPD52L2 PE=1 SV=1 28123 MDSAGQDINLNSPNKGLLSDSMTDVPVDTGVAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELKQNLSRSWHDVQVSSAYVKTSEKLGEWNEKVTQSDLYKKTQETLSQAGQKTSAALSTVGSAISRKLGDMSLRLWVTERTAVTTSLPQRGVVTSPCRIPHLSKPVVASPAAEHTQPSLSITAAALFSGAASQGG 118 10.8 5 6 6 2 2 0.719 0.728 0.693 4 4 4 - - - 0.713333333 0.018175075 tr|A0A087WYR3|A0A087WYR3_HUMAN 100 2.00E-70 gi|40805864|ref|NP_955392.1| tumor protein D54 isoform a [Homo sapiens] >gi|119595605|gb|EAW75199.1| tumor protein D52-like 2, isoform CRA_e [Homo sapiens] 100 4.00E-71 sp|O43399|TPD54_HUMAN Tumor protein D54 OS=Homo sapiens GN=TPD52L2 PE=1 SV=2 100 9.00E-50 B4DDV4 B4DDV4_HUMAN cDNA FLJ52530, highly similar to Tumor protein D54 OS=Homo sapiens PE=2 SV=1 - - - - - - - - GO:0042127//regulation of cell proliferation GO:0042803//protein homodimerization activity GO:0048471//perinuclear region of cytoplasm 284 tr|B4DNU9|B4DNU9_HUMAN cDNA FLJ55731, highly similar to Polymerase I and transcript release factor OS=Homo sapiens PE=2 SV=1 52799 MEDPTLYIVERPLPGYPDAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLDKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKSFTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEMVEVGADDDEGGAERGEAGDLRRGSSPDVHALLEITEESDAVLVDKSDSD 237 12.6 2 8 8 4 4 1.073 0.959 0.874 4 5 4 - - - 0.968666667 0.099851556 tr|B4DNU9|B4DNU9_HUMAN 100 3.00E-76 gi|14250760|gb|AAH08849.1| PTRF protein [Homo sapiens] 95.13 2.00E-140 sp|Q6NZI2|PTRF_HUMAN Polymerase I and transcript release factor OS=Homo sapiens GN=PTRF PE=1 SV=1 100 6.00E-143 B4DNU9 B4DNU9_HUMAN cDNA FLJ55731, highly similar to Polymerase I and transcript release factor OS=Homo sapiens PE=2 SV=1 - - - - - - - - GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter GO:0042134//rRNA primary transcript binding;GO:0005515//protein binding GO:0005739//mitochondrion;GO:0005901//caveola;GO:0005654//nucleoplasm 285 sp|O75368|SH3L1_HUMAN SH3 domain-binding glutamic acid-rich-like protein OS=Homo sapiens GN=SH3BGRL PE=1 SV=1 >tr|V9HW48|V9HW48_HUMAN SH3 domain-binding glutamic acid-rich-like protein OS=Homo sapiens GN=HEL-S-115 PE=2 SV=1 15504 MVIRVYIASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPATGYPLPPQIFNESQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAEVQAKQQA 303 59.6 - 11 11 5 5 0.833 0.655 0.927 10 9 10 - * - 0.805 0.138144852 sp|O75368|SH3L1_HUMAN 100 2.00E-55 gi|291407934|ref|XP_002720284.1| PREDICTED: SH3 domain binding glutamic acid-rich protein like [Oryctolagus cuniculus] 100 1.00E-61 sp|O75368|SH3L1_HUMAN SH3 domain-binding glutamic acid-rich-like protein OS=Homo sapiens GN=SH3BGRL PE=1 SV=1 100 5.00E-60 G1QQ20 G1QQ20_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=SH3BGRL PE=4 SV=1 - - - - - - - - - GO:0017124//SH3 domain binding;GO:0005070//SH3/SH2 adaptor activity GO:0005737//cytoplasm;GO:0005634//nucleus 286 tr|B7Z6Q5|B7Z6Q5_HUMAN Beta-galactosidase OS=Homo sapiens PE=2 SV=1 92551 MPGFLVRILLLLLVLLLLGPTRGLRSRFLPWAFHLPRQAPKSQLPLHKRGTKTAPNEHASSNRSGRRRRRQQWNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV 182 4.8 3 12 12 3 3 0.928 0.942 0.795 5 5 5 - - - 0.888333333 0.08113158 tr|B7Z6Q5|B7Z6Q5_HUMAN 100 0 gi|119372312|ref|NP_001073279.1| beta-galactosidase isoform b [Homo sapiens] 93.24 0 sp|P16278|BGAL_HUMAN Beta-galactosidase OS=Homo sapiens GN=GLB1 PE=1 SV=2 100 0 B7Z6Q5 B7Z6Q5_HUMAN Beta-galactosidase OS=Homo sapiens PE=2 SV=1 XF0840 352 9.00E-97 COG1874 Beta-galactosidase G Carbohydrate transport and metabolism ; K12309|1|0.0|1355|hsa:2720|beta-galactosidase [EC:3.2.1.23] GO:0006644//phospholipid metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0019388//galactose catabolic process;GO:0042340//keratan sulfate catabolic process;GO:0044281//small molecule metabolic process GO:0043169//cation binding;GO:0016936//galactoside binding;GO:0004565//beta-galactosidase activity;GO:0005515//protein binding GO:0043202//lysosomal lumen;GO:0048471//perinuclear region of cytoplasm 287 tr|C9J592|C9J592_HUMAN Ras-related protein Rab-7a (Fragment) OS=Homo sapiens GN=RAB7A PE=1 SV=1 21152 MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIP 202 41.3 1 13 13 5 5 0.935 0.658 0.791 7 7 7 - - - 0.794666667 0.138536397 tr|C9J592|C9J592_HUMAN 100 5.00E-85 gi|348551446|ref|XP_003461541.1| PREDICTED: ras-related protein Rab-7a-like [Cavia porcellus] 100 4.00E-86 sp|P09527|RAB7A_RAT Ras-related protein Rab-7a OS=Rattus norvegicus GN=Rab7a PE=1 SV=2 100 2.00E-84 H2P9E8 H2P9E8_PONAB Ras-related protein Rab-7a OS=Pongo abelii GN=RAB7A PE=3 SV=1 SPAC18G6.03 113 1.00E-25 COG1100 GTPase SAR1 and related small G proteins R General function prediction only ; K07897|1|4e-86|316|rno:29448|Ras-related protein Rab-7A GO:0090382//phagosome maturation;GO:0045453//bone resorption;GO:0006184//GTP catabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007264//small GTPase mediated signal transduction;GO:0006897//endocytosis;GO:0008333//endosome to lysosome transport;GO:0006622//protein targeting to lysosome;GO:0045022//early endosome to late endosome transport;GO:0007174//epidermal growth factor catabolic process GO:0005525//GTP binding;GO:0048365//Rac GTPase binding;GO:0019003//GDP binding;GO:0003924//GTPase activity GO:0097208//alveolar lamellar body;GO:0045335//phagocytic vesicle;GO:0042470//melanosome;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005770//late endosome 288 tr|J3KNE3|J3KNE3_HUMAN Platelet-activating factor acetylhydrolase IB subunit beta (Fragment) OS=Homo sapiens GN=PAFAH1B2 PE=1 SV=1 21502 AAAGAGAGGGTRRSGTDGTERATDAPPADASAAWGPHGPSTSVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA 206 5.1 1 5 5 1 1 0.649 1.082 0.49 3 4 4 - - - 0.740333333 0.306385922 tr|J3KNE3|J3KNE3_HUMAN 100 2.00E-12 gi|296080770|ref|NP_001171677.1| platelet-activating factor acetylhydrolase IB subunit beta isoform d [Homo sapiens] >gi|114228427|gb|ABI58225.1| intracellular platelet-activating factor acetylhydrolase alpha 2 subunit variant 5 [Homo sapiens] 100 2.00E-72 sp|P68401|PA1B2_BOVIN Platelet-activating factor acetylhydrolase IB subunit beta OS=Bos taurus GN=PAFAH1B2 PE=1 SV=1 100 5.00E-71 G1P9W0 G1P9W0_MYOLU Uncharacterized protein OS=Myotis lucifugus GN=PAFAH1B2 PE=4 SV=1 - - - - - - - K01062|1|2e-73|274|cfa:479425|1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47] GO:0016042//lipid catabolic process;GO:0007420//brain development;GO:0007283//spermatogenesis;GO:0006928//cellular component movement;GO:0016239//positive regulation of macroautophagy GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0047179//platelet-activating factor acetyltransferase activity GO:0005829//cytosol 289 tr|Q53FK2|Q53FK2_HUMAN Stress 70 protein chaperone, microsome-associated, 60kDa variant (Fragment) OS=Homo sapiens PE=2 SV=1 61075 MAREMTILGSAVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTICDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVTSNETITVSPEYVGSRLLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHKADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSALEIPNKHLQKTNFN 277 11.7 1 17 17 5 5 1.691 1.332 1.62 11 12 12 * * * 1.547666667 0.190116631 tr|Q53FK2|Q53FK2_HUMAN 100 0 gi|62898125|dbj|BAD97002.1| stress 70 protein chaperone, microsome-associated, 60kDa precursor variant [Homo sapiens] 99.79 0 sp|P48723|HSP13_HUMAN Heat shock 70 kDa protein 13 OS=Homo sapiens GN=HSPA13 PE=1 SV=1 100 0 Q53FK2 Q53FK2_HUMAN Stress 70 protein chaperone, microsome-associated, 60kDa variant (Fragment) OS=Homo sapiens PE=2 SV=1 YAL005c 292 7.00E-79 COG0443 Molecular chaperone O Posttranslational modification, protein turnover, chaperones ; K09491|1|0.0|921|hsa:6782|stress 70 protein chaperone microsome-associated 60kDa protein - GO:0005524//ATP binding GO:0005783//endoplasmic reticulum 290 tr|B2RDY9|B2RDY9_HUMAN Adenylyl cyclase-associated protein OS=Homo sapiens PE=2 SV=1 65557 MADMQNLVERLERAVGRLEAVSHTSDMHRGYADSPSKAGAAPYVQAFDSLLAGPVAEYLKISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPISEQIKEVITFREKNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKKHVDWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFGDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG 297 10.7 5 13 13 4 4 0.578 0.594 0.538 9 9 9 * * * 0.57 0.02884441 tr|B2RDY9|B2RDY9_HUMAN 100 0 gi|189055102|dbj|BAG38086.1| unnamed protein product [Homo sapiens] 98.53 0 sp|Q01518|CAP1_HUMAN Adenylyl cyclase-associated protein 1 OS=Homo sapiens GN=CAP1 PE=1 SV=5 100 0 B2RDY9 B2RDY9_HUMAN Adenylyl cyclase-associated protein OS=Homo sapiens PE=2 SV=1 - - - - - - - - GO:0050688//regulation of defense response to virus;GO:0034138//toll-like receptor 3 signaling pathway;GO:0007411//axon guidance;GO:0034142//toll-like receptor 4 signaling pathway;GO:0008063//Toll signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0030162//regulation of proteolysis;GO:0001667//ameboidal cell migration;GO:0030168//platelet activation;GO:0007163//establishment or maintenance of cell polarity;GO:0006898//receptor-mediated endocytosis;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0002576//platelet degranulation;GO:0032648//regulation of interferon-beta production;GO:0032480//negative regulation of type I interferon production;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0030036//actin cytoskeleton organization;GO:0006917//induction of apoptosis GO:0004871//signal transducer activity;GO:0031625//ubiquitin protein ligase binding;GO:0004842//ubiquitin-protein ligase activity;GO:0008270//zinc ion binding;GO:0031996//thioesterase binding;GO:0003779//actin binding GO:0005829//cytosol;GO:0030864//cortical actin cytoskeleton;GO:0009898//internal side of plasma membrane;GO:0005739//mitochondrion;GO:0035631//CD40 receptor complex;GO:0005768//endosome 291 tr|G3V0G6|G3V0G6_HUMAN Elastin OS=Homo sapiens GN=ELN PE=4 SV=1 71141 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRKRK 391 14.1 6 17 6 5 3 1.356 2.699 2.109 5 5 5 - * * 2.054666667 0.673146591 tr|G3V0G6|G3V0G6_HUMAN 96.15 7.00E-06 gi|395843015|ref|XP_003794299.1| PREDICTED: uncharacterized protein LOC100965101 [Otolemur garnettii] 100 2.00E-06 sp|P15502|ELN_HUMAN Elastin OS=Homo sapiens GN=ELN PE=1 SV=3 - - - - - - - - - - - K14211|1|2e-06|55.1|hsa:2006|elastin - - 292 tr|A0A024RDB4|A0A024RDB4_HUMAN Heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa), isoform CRA_c OS=Homo sapiens GN=HNRPD PE=4 SV=1 46459 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGYSNYWNQGYGNYGYNSQGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY 223 15.5 6 20 9 5 4 0.859 0.75 0.869 5 5 5 - - - 0.826 0.066007575 tr|A0A024RDB4|A0A024RDB4_HUMAN 100 7.00E-97 gi|471400742|ref|XP_004383160.1| PREDICTED: heterogeneous nuclear ribonucleoprotein D0 isoform 4 [Trichechus manatus latirostris] 100 2.00E-59 sp|P17132|HNRPC_RAT Heterogeneous nuclear ribonucleoprotein C (Fragment) OS=Rattus norvegicus GN=Hnrnpc PE=2 SV=1 100 2.00E-96 F7APF4 F7APF4_MACMU Uncharacterized protein OS=Macaca mulatta GN=HNRNPD PE=4 SV=1 SPAC140.02 77.8 3.00E-14 COG0724 RNA-binding proteins (RRM domain) R General function prediction only ; K13044|1|1e-103|376|mcc:694867|heterogeneous nuclear ribonucleoprotein A/B/D GO:0000398//mRNA splicing, via spliceosome;GO:0006913//nucleocytoplasmic transport;GO:0048255//mRNA stabilization;GO:0000291//nuclear-transcribed mRNA catabolic process, exonucleolytic;GO:0045893//positive regulation of transcription, DNA-dependent GO:0042162//telomeric DNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding GO:0005829//cytosol;GO:0005730//nucleolus;GO:0030529//ribonucleoprotein complex;GO:0005654//nucleoplasm 293 sp|Q07954|LRP1_HUMAN Prolow-density lipoprotein receptor-related protein 1 OS=Homo sapiens GN=LRP1 PE=1 SV=2 576082 MLTPPLLLLLPLLSALVAAAIDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFICGCVEGYLLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMPGLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSDNANAQQKTSVIRVNRFNSTEYQVVTRVDKGGALHIYHQRRQPRVRSHACENDQYGKPGGCSDICLLANSHKARTCRCRSGFSLGSDGKSCKKPEHELFLVYGKGRPGIIRGMDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVEGVAVDWMGDNLYWTDDGPKKTISVARLEKAAQTRKTLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGSVYRLERGVGGAPPTVTLLRSERPPIFEIRMYDAQQQQVGTNKCRVNNGGCSSLCLATPGSRQCACAEDQVLDADGVTCLANPSYVPPPQCQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGRCININWRCDNDNDCGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCANNTSVCLPPDKLCDGNDDCGDGSDEGELCDQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGPDNHTCQIQSYCAKHLKCSQKCDQNKFSVKCSCYEGWVLEPDGESCRSLDPFKPFIIFSNRHEIRRIDLHKGDYSVLVPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTVHRETGSGGWPNGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTGHNVTVVQRTNTQPFDLQVYHPSRQPMAPNPCEANGGQGPCSHLCLINYNRTVSCACPHLMKLHKDNTTCYEFKKFLLYARQMEIRGVDLDAPYYNYIISFTVPDIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTGVETVVSADLPNAHGLAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQGLEQPHGLVVHPLRGKLYWTDGDNISMANMDGSNRTLLFSGQKGPVGLAIDFPESKLYWISSGNHTINRCNLDGSGLEVIDAMRSQLGKATALAIMGDKLWWADQVSEKMGTCSKADGSGSVVLRNSTTLVMHMKVYDESIQLDHKGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSGQQACEGVGSFLLYSVHEGIRGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWGQYPRIERSRLDGTERVVLVNVSISWPNGISVDYQDGKLYWCDARTDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGSIKRGSKDNATDSVPLRTGIGVQLKDIKVFNRDRQKGTNVCAVANGGCQQLCLYRGRGQRACACAHGMLAEDGASCREYAGYLLYSERTILKSIHLSDERNLNAPVQPFEDPEHMKNVIALAFDYRAGTSPGTPNRIFFSDIHFGNIQQINDDGSRRITIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDDHPRAFVLDECQNLMFWTNWNEQHPSIMRAALSGANVLTLIEKDIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDWVRRAVQRANKHVGSNMKLLRVDIPQQPMGIIAVANDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQDDLTCRAVNSSCRAQDEFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVSNMLWCNGADDCGDGSDEIPCNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCEHGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFRCANGRCLSSRQWECDGENDCHDQSDEAPKNPHCTSQEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGCHINECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLKDDGRTCADVDECSTTFPCSQRCINTHGSYKCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVALDFDYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSSGLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSSRSVIVDTKITWPNGLTLDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTLFEDYVYWTDWETKSINRAHKTTGTNKTLLISTLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGGGHKCACPTNFYLGSDGRTCVSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINECLRFGTCSQLCNNTKGGHLCSCARNFMKTHNTCKAEGSEYQVLYIADDNEIRSLFPGHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHLNISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKFGHSPLVNLTGGLSHASDVVLYHQHKQPEVTNPCDRKKCEWLCLLSPSGPVCTCPNGKRLDNGTCVPVPSPTPPPDAPRPGTCNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYFEGSRCEVNKCSRCLEGACVVNKQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPPHMTGPRCEEHVFSQQQPGHIASILIPLLLLLLLVLVAGVVFWYKRRVQGAKGFQHQRMTNGAMNVEIGNPTYKMYEGGEPDDVGGLLDADFALDPDKPTNFTNPVYATLYMGGHGSRHSLASTDEKRELLGRGPEDEIGDPLA 615 4.5 - 44 44 17 17 1.303 1.293 1.33 26 28 28 * - - 1.308666667 0.019139836 sp|Q07954|LRP1_HUMAN 100 0 gi|126012562|ref|NP_002323.2| prolow-density lipoprotein receptor-related protein 1 precursor [Homo sapiens] >gi|317373384|sp|Q07954.2|LRP1_HUMAN RecName: Full=Prolow-density lipoprotein receptor-related protein 1; Short=LRP-1; AltName: Full=Alpha-2-macroglobulin receptor; Short=A2MR; AltName: Full=Apolipoprotein E receptor; Short=APOER; AltName: CD_antigen=CD91; Contains: RecName: Full=Low-density lipoprotein receptor-related protein 1 85 kDa subunit; Short=LRP-85; Contains: RecName: Full=Low-density lipoprotein receptor-related protein 1 515 kDa subunit; Short=LRP-515; Contains: RecName: Full=Low-density lipoprotein receptor-related protein 1 intracellular domain; Short=LRPICD; Flags: Precursor 100 0 sp|Q07954|LRP1_HUMAN Prolow-density lipoprotein receptor-related protein 1 OS=Homo sapiens GN=LRP1 PE=1 SV=2 100 0 Q6LBN5 Q6LBN5_HUMAN Alpha-2 macroglobulin receptor (Fragment) OS=Homo sapiens PE=2 SV=1 MT0958_2 53.5 8.00E-06 COG3391 Uncharacterized conserved protein S Function unknown ; K04550|1|0.0|8929|hsa:4035|low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) GO:0042953//lipoprotein transport;GO:0035909//aorta morphogenesis;GO:0006898//receptor-mediated endocytosis;GO:0007568//aging;GO:2000587//negative regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:0008283//cell proliferation;GO:0008203//cholesterol metabolic process;GO:0010875//positive regulation of cholesterol efflux;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0042157//lipoprotein metabolic process;GO:0030178//negative regulation of Wnt receptor signaling pathway;GO:0014912//negative regulation of smooth muscle cell migration;GO:0032956//regulation of actin cytoskeleton organization;GO:0051222//positive regulation of protein transport;GO:0032429//regulation of phospholipase A2 activity;GO:0043277//apoptotic cell clearance;GO:0097242//beta-amyloid clearance GO:0005041//low-density lipoprotein receptor activity;GO:0005509//calcium ion binding;GO:0070325//lipoprotein particle receptor binding;GO:0002020//protease binding;GO:0032403//protein complex binding;GO:0042954//lipoprotein transporter activity;GO:0034185//apolipoprotein binding GO:0005905//coated pit;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0005768//endosome;GO:0048471//perinuclear region of cytoplasm;GO:0030136//clathrin-coated vesicle;GO:0005887//integral to plasma membrane;GO:0005634//nucleus 294 tr|J3KR44|J3KR44_HUMAN Ubiquitin thioesterase OTUB1 OS=Homo sapiens GN=OTUB1 PE=1 SV=2 37124 MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLHKKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRRFKAVSAKSKEDLVSQGFTEFTIEDFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYMDRGEGGTTNPHIFPEGSEPKVYLLYRPGHYDILYK 125 12.1 5 8 8 3 3 0.942 0.999 0.803 4 5 5 - - - 0.914666667 0.100818318 tr|J3KR44|J3KR44_HUMAN 99.63 5.00E-151 gi|52545531|emb|CAH56412.1| hypothetical protein [Homo sapiens] 99.63 9.00E-151 sp|Q96FW1|OTUB1_HUMAN Ubiquitin thioesterase OTUB1 OS=Homo sapiens GN=OTUB1 PE=1 SV=2 100 2.00E-07 F5H3F0 F5H3F0_HUMAN Ubiquitin thioesterase OTUB1 OS=Homo sapiens GN=OTUB1 PE=4 SV=1 ECU05g0570 57.8 2.00E-08 COG5539 Predicted cysteine protease (OTU family) O Posttranslational modification, protein turnover, chaperones ; K09602|1|1e-150|532|ssc:100302092|ubiquitin thioesterase protein OTUB1 [EC:3.4.-.-] GO:2000780//negative regulation of double-strand break repair;GO:0006508//proteolysis;GO:1901315//negative regulation of histone H2A K63-linked ubiquitination;GO:0071108//protein K48-linked deubiquitination GO:0008242//omega peptidase activity;GO:0019784//NEDD8-specific protease activity;GO:0031625//ubiquitin protein ligase binding;GO:0043130//ubiquitin binding;GO:0004843//ubiquitin-specific protease activity GO:0005737//cytoplasm 295 tr|B4E2U0|B4E2U0_HUMAN 6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens PE=2 SV=1 62224 MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTNGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSSYNA 297 15.4 1 17 17 6 6 1.423 0.994 0.948 13 12 13 - - - 1.121666667 0.261973917 tr|B4E2U0|B4E2U0_HUMAN 100 0 gi|194385754|dbj|BAG65252.1| unnamed protein product [Homo sapiens] 95.24 0 sp|P52209|6PGD_HUMAN 6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens GN=PGD PE=1 SV=3 100 0 B4E2U0 B4E2U0_HUMAN 6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens PE=2 SV=1 VCA0898 627 1.00E-179 COG0362 6-phosphogluconate dehydrogenase G Carbohydrate transport and metabolism ; K00033|1|0.0|917|hsa:5226|6-phosphogluconate dehydrogenase [EC:1.1.1.44]!K10392|2|0.0|877|mcc:722674|kinesin family member 1/13/14 GO:0019322//pentose biosynthetic process;GO:0009051//pentose-phosphate shunt, oxidative branch GO:0050661//NADP binding;GO:0004616//phosphogluconate dehydrogenase (decarboxylating) activity GO:0005829//cytosol 296 tr|Q5TZP0|Q5TZP0_HUMAN Matrix metalloproteinase 1 (Interstitial collagenase) OS=Homo sapiens PE=2 SV=1 63549 MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGMQVEKRRNSGPVVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDRFYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN 3031 35.4 4 150 21 14 1 0.581 0.606 0.667 15 15 15 - * * 0.618 0.044237993 tr|Q5TZP0|Q5TZP0_HUMAN 100 0 gi|54697154|gb|AAV38949.1| matrix metalloproteinase 1 (interstitial collagenase) [Homo sapiens] 99.79 0 sp|P03956|MMP1_HUMAN Interstitial collagenase OS=Homo sapiens GN=MMP1 PE=1 SV=3 100 0 Q5TZP0 Q5TZP0_HUMAN Matrix metalloproteinase 1 (Interstitial collagenase) OS=Homo sapiens PE=2 SV=1 - - - - - - - K01388|1|0.0|973|ptr:451510|matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7] GO:0022617//extracellular matrix disassembly;GO:0050900//leukocyte migration;GO:0006508//proteolysis;GO:0019048//virus-host interaction;GO:0030574//collagen catabolic process;GO:0007596//blood coagulation GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0004222//metalloendopeptidase activity GO:0005578//proteinaceous extracellular matrix 297 tr|M0R0Y2|M0R0Y2_HUMAN Alpha-soluble NSF attachment protein OS=Homo sapiens GN=NAPA PE=1 SV=1 36787 MDNSGKEAEAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAANMFKMAKNWSEAINCLMRAIEIYTDMGRFTIAAKHHISIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAALLEQYQKAIDIYEQVGTNAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRECKLMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKKTIQGDEEDLR 90 10.9 2 2 2 2 2 0.686 0.636 0.67 2 2 2 - * - 0.664 0.025534291 tr|M0R0Y2|M0R0Y2_HUMAN 100 5.00E-63 gi|119577894|gb|EAW57490.1| N-ethylmaleimide-sensitive factor attachment protein, alpha, isoform CRA_b [Homo sapiens] >gi|119577897|gb|EAW57493.1| N-ethylmaleimide-sensitive factor attachment protein, alpha, isoform CRA_b [Homo sapiens] 86.78 2.00E-125 sp|P54920|SNAA_HUMAN Alpha-soluble NSF attachment protein OS=Homo sapiens GN=NAPA PE=1 SV=3 100 2.00E-107 F6Z9C3 F6Z9C3_MACMU Uncharacterized protein OS=Macaca mulatta GN=Mmu.19386 PE=4 SV=1 - - - - - - - K15296|1|2e-125|448|mcc:717355|alpha-soluble NSF attachment protein GO:0045176//apical protein localization;GO:0043129//surfactant homeostasis;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006944//cellular membrane fusion;GO:0006886//intracellular protein transport;GO:0035249//synaptic transmission, glutamatergic;GO:0007420//brain development;GO:0035494//SNARE complex disassembly;GO:0010807//regulation of synaptic vesicle priming;GO:0006892//post-Golgi vesicle-mediated transport;GO:0033619//membrane protein proteolysis;GO:0030182//neuron differentiation GO:0004190//aspartic-type endopeptidase activity;GO:0019905//syntaxin binding GO:0097208//alveolar lamellar body;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005829//cytosol;GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex 298 tr|A0A087X0K0|A0A087X0K0_HUMAN Collagen alpha-1(XV) chain OS=Homo sapiens GN=COL15A1 PE=4 SV=1 156855 MLLSVSTPLPAVTQTRGATETASQGHLDLTQLIGVPLPSSVSFVTGYGGFPAYSFGPGANVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSGVEDGHQRIILYYTEPGSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEESSASGETSGLQEADGVAEILEAVTYTQASPKEAKVEPINTPPTPSSPFEDMELSGEPVPEGTLETTNMSIIQHSSPKQGKGAILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVPISTAGEAEASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDMLQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQLGELIPIPADSPPPPALSSNPHQLLPPPNPISSANYEKPALHLAALNMPFSGDIRADFQCFKQARAAGLLSTYRAFLSSHLQDLSTIVRKAERYSLPIVNLKGQVLFNNWDSIFSGHGGQFNMHIPIYSFDGRDIMTDPSWPQKVIWHGSSPHGVRLVDNYCEAWRTADTAVTGLASPLSTGKILDQKAYSCANRLIVLCIENSFMTDARK 793 9.4 1 37 37 10 10 2.155 3.573 3.432 21 20 17 * * * 3.053333333 0.781167289 tr|A0A087X0K0|A0A087X0K0_HUMAN 100 0 gi|119579303|gb|EAW58899.1| collagen, type XV, alpha 1, isoform CRA_a [Homo sapiens] 99.85 0 sp|P39059|COFA1_HUMAN Collagen alpha-1(XV) chain OS=Homo sapiens GN=COL15A1 PE=1 SV=2 99.03 0 F5H1A4 F5H1A4_HUMAN Endostatin OS=Homo sapiens GN=COL15A1 PE=4 SV=1 - - - - - - - K08135|1|0.0|1857|hsa:1306|collagen, type XV, alpha GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0032502//developmental process;GO:0030198//extracellular matrix organization GO:0005201//extracellular matrix structural constituent GO:0016021//integral to membrane;GO:0005615//extracellular space;GO:0005582//collagen type XV;GO:0005788//endoplasmic reticulum lumen 299 tr|B2R892|B2R892_HUMAN cDNA, FLJ93793, highly similar to Homo sapiens creatine kinase, muscle (CKM), mRNA OS=Homo sapiens PE=2 SV=1 54181 MPFGNTHNKFKLNYKPGEEYPDLSKHNNHMAKVLTLELYKKLRDKETPSGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKPTDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK 549 8.1 2 23 23 2 2 0.715 0.776 1.231 19 19 15 * * * 0.907333333 0.281958035 tr|B2R892|B2R892_HUMAN 100 0 gi|189053833|dbj|BAG36089.1| unnamed protein product [Homo sapiens] 99.74 0 sp|P06732|KCRM_HUMAN Creatine kinase M-type OS=Homo sapiens GN=CKM PE=1 SV=2 100 0 B2R892 B2R892_HUMAN cDNA, FLJ93793, highly similar to Homo sapiens creatine kinase, muscle (CKM), mRNA OS=Homo sapiens PE=2 SV=1 CAC3190 91.7 2.00E-18 COG3869 Arginine kinase E Amino acid transport and metabolism ; K00933|1|0.0|758|hsa:1158|creatine kinase [EC:2.7.3.2] GO:0006600//creatine metabolic process;GO:0046314//phosphocreatine biosynthetic process;GO:0016310//phosphorylation;GO:0034641//cellular nitrogen compound metabolic process GO:0004111//creatine kinase activity;GO:0005524//ATP binding GO:0005829//cytosol 300 tr|J9JID7|J9JID7_HUMAN Lamin B2, isoform CRA_a OS=Homo sapiens GN=LMNB2 PE=1 SV=1 82188 MSPPSPGRRREQRRPRAAATMATPLPGRAGGPATPLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLKISEKEEVTTREVSGIKALYESELADARRVLDETARERARLQIEIGKLRAELDEVNKSAKKREGELTVAQGRVKDLESLFHRSEVELAAALSDKRGLESDVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELDFRKSVFEEEVRETRRRHERRLVEVDSSRQQEYDFKMAQALEELRSQHDEQVRLYKLELEQTYQAKLDSAKLSSDQNDKAASAAREELKEARMRLESLSYQLSGLQKQASAAEDRIRELEEAMAGERDKFRKMLDAKEQEMTEMRDVMQQQLAEYQELLDVKLALDMEINAYRKLLEGEEERLKLSPSPSSRVTVSRATSSSSGSLSATGRLGRSKRKRLEVEEPLGSGPSVLGTGTGGSGGFHLAQQASASGSVSIEEIDLEGKFVQLKNNSDKDQSLGNWRIKRQVLEGEEIAYKFTPKYILRAGQMVTVWAAGAGVAHSPPSTLVWKGQSSWGTGESFRTVLVNADGEEVAMRTVKKSSVMRENENGEEEEEEAEFGEEDLFHQQGDPRTTSRGCYVM 48 2.1 1 2 2 2 2 1.271 1.986 2.149 2 2 2 - - * 1.802 0.467025695 tr|J9JID7|J9JID7_HUMAN 100 2.00E-140 gi|345758|pir||A45023 lamin B2 - human (fragment) >gi|1054874|gb|AAA80979.1| lamin B2, partial [Homo sapiens] 100 0 sp|Q03252|LMNB2_HUMAN Lamin-B2 OS=Homo sapiens GN=LMNB2 PE=1 SV=3 99.62 0 G3QLP4 G3QLP4_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=LMNB2 PE=3 SV=1 - - - - - - - K07611|1|0.0|959|hsa:84823|lamin B - GO:0005198//structural molecule activity GO:0005638//lamin filament;GO:0005637//nuclear inner membrane 301 tr|H0YHX9|H0YHX9_HUMAN Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Fragment) OS=Homo sapiens GN=NACA PE=1 SV=1 28405 TVAAFPLESADPAGVAPTTAKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 168 19.7 6 7 7 3 3 1.43 1.191 1.498 6 6 6 * - * 1.373 0.161242054 tr|H0YHX9|H0YHX9_HUMAN 100 5.00E-15 gi|395835521|ref|XP_003790726.1| PREDICTED: uncharacterized protein LOC100943452 [Otolemur garnettii] 98.96 2.00E-86 sp|P70670|NACAM_MOUSE Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Mus musculus GN=Naca PE=1 SV=2 100 3.00E-85 E9PAV3 E9PAV3_HUMAN Nascent polypeptide-associated complex subunit alpha OS=Homo sapiens GN=NACA PE=4 SV=1 SPBC25H2.05 130 2.00E-30 COG1308 Transcription factor homologous to NACalpha-BTF3 K Transcription ; K03626|1|2e-86|318|mmu:17938|nascent polypeptide-associated complex subunit alpha GO:0006355//regulation of transcription, DNA-dependent;GO:0015031//protein transport GO:0017025//TBP-class protein binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity GO:0005737//cytoplasm;GO:0005634//nucleus 302 tr|B4DXN0|B4DXN0_HUMAN cDNA FLJ53371, highly similar to Major vault protein OS=Homo sapiens PE=2 SV=1 105726 MATEEFIIRIPPYHYIHVLFDVTGQVRLRHADLEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTALHLKALLDFEDKDGDKVVAGDEWLFEGPGTYIPRKEVEVVEIIQATIIRQNQALRLRARKECWDRDGKERVTGEEWLVTTVGAYLPAVFEEVLDLVDAVILTEKTALHLRARRNFRDFRGVSRRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPHNYCVILDPVGPDGKNQLGQKRVVKSFFLQPGEQLEQGIQDVYVLSEQQGLLLRALQPLEEGEDEEKVSHQAGDHWLIRGPLEYVPSAKVEVVEERQAIPLDENEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELPPGVEELLNKGQDPLADRGEKDTAKSLQPSAPRNKTRVVSYRVPHNAAVQVYDYREKRARVVFGPELVSLGPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQLAYNWHFEVNDRKDPQETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIRTAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLELEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTPINLFNTAFGLLGMGPEGQPLGRRVASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 223 9.1 3 13 13 6 6 1.886 1.169 1.255 7 7 4 * - - 1.436666667 0.391502661 tr|B4DXN0|B4DXN0_HUMAN 100 3.00E-18 gi|298561240|dbj|BAJ09627.1| lung resistance-associated protein [Canis lupus familiaris] 93.28 0 sp|Q14764|MVP_HUMAN Major vault protein OS=Homo sapiens GN=MVP PE=1 SV=4 100 1.00E-17 D6RUR0 D6RUR0_CANFA Lung resistance-associated protein (Fragment) OS=Canis familiaris GN=LRP PE=2 SV=1 - - - - - - - - GO:0042493//response to drug;GO:0051028//mRNA transport;GO:0015031//protein transport GO:0005515//protein binding GO:0005737//cytoplasm;GO:0005643//nuclear pore;GO:0030529//ribonucleoprotein complex 303 sp|Q6EMK4|VASN_HUMAN Vasorin OS=Homo sapiens GN=VASN PE=1 SV=1 75489 MCSRVPLLLPLLLLLALGPGVQGCPSGCQCSQPQTVFCTARQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPFNCVCPLSWFGPWVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFGCPATTTTATVPTTRPVVREPTALSSSLAPTWLSPTEPATEAPSPPSTAPPTVGPVPQPQDCPPSTCLNGGTCHLGTRHHLACLCPEGFTGLYCESQMGQGTRPSPTPVTPRPPRSLTLGIEPVSPTSLRVGLQRYLQGSSVQLRSLRLTYRNLSGPDKRLVTLRLPASLAEYTVTQLRPNATYSVCVMPLGPGRVPEGEEACGEAHTPPAVHSNHAPVTQAREGNLPLLIAPALAAVLLAALAAVGAAYCVRRGRAMAAAAQDKGQVGPGAGPLELEGVKVPLEPGPKATEGGGEALPSGSECEVPLMGFPGPGLQSPLHAKPYI 165 6.2 - 6 6 3 3 0.956 0.906 1.111 5 5 5 - - - 0.991 0.106887792 sp|Q6EMK4|VASN_HUMAN 100 0 gi|88702793|ref|NP_612449.2| vasorin precursor [Homo sapiens] >gi|74748436|sp|Q6EMK4.1|VASN_HUMAN RecName: Full=Vasorin; AltName: Full=Protein slit-like 2; Flags: Precursor >gi|37725933|gb|AAO27704.1| vasorin [Homo sapiens] >gi|119605717|gb|EAW85311.1| slit-like 2 (Drosophila) [Homo sapiens] 100 0 sp|Q6EMK4|VASN_HUMAN Vasorin OS=Homo sapiens GN=VASN PE=1 SV=1 100 4.00E-64 G3RTL2 G3RTL2_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=VASN PE=4 SV=1 alr0124_1 76.3 2.00E-13 COG4886 Leucine-rich repeat (LRR) protein S Function unknown ; K07523|1|7e-21|102|xtr:100188921|netrin-G1 ligand - - GO:0016020//membrane 304 tr|B2R582|B2R582_HUMAN cDNA, FLJ92374, highly similar to Homo sapiens C-type lectin domain family 3, member B (CLEC3B), mRNA OS=Homo sapiens PE=2 SV=1 28093 MELWGAYLLLCLFSLLTQVTTEPPTQKPKKIVNAKKDVVNTKMFEVLKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLSTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV 826 22.8 2 28 28 4 4 0.323 0.261 0.292 24 24 22 * * - 0.292 0.031 tr|B2R582|B2R582_HUMAN 100 1.00E-116 gi|189065306|dbj|BAG35029.1| unnamed protein product [Homo sapiens] 99.01 4.00E-116 sp|P05452|TETN_HUMAN Tetranectin OS=Homo sapiens GN=CLEC3B PE=1 SV=3 100 6.00E-75 Q68DS3 Q68DS3_HUMAN Putative uncharacterized protein DKFZp686H17246 (Fragment) OS=Homo sapiens GN=DKFZp686H17246 PE=2 SV=1 - - - - - - - K12589|1|1e-115|415|pon:100458989|exosome complex component RRP42!K10068|5|1e-13|76.3|bta:282072|surfactant, pulmonary-associated protein D GO:0001501//skeletal system development;GO:0030282//bone mineralization;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0010756//positive regulation of plasminogen activation GO:0005509//calcium ion binding;GO:0036143//kringle domain binding;GO:0008201//heparin binding GO:0005615//extracellular space;GO:0001652//granular component;GO:0031012//extracellular matrix;GO:0005737//cytoplasm 305 tr|B4DH02|B4DH02_HUMAN cDNA FLJ50510, highly similar to Heat shock 70 kDa protein 4 OS=Homo sapiens PE=2 SV=1 120101 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDTTQIAGLNCLRLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVFSKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMDID 276 13.7 3 16 12 8 7 0.654 0.708 0.722 8 8 8 * * - 0.694666667 0.035907288 tr|B4DH02|B4DH02_HUMAN 100 0 gi|194378426|dbj|BAG57963.1| unnamed protein product [Homo sapiens] 99.88 0 sp|P34932|HSP74_HUMAN Heat shock 70 kDa protein 4 OS=Homo sapiens GN=HSPA4 PE=1 SV=4 100 0 B4E354 B4E354_HUMAN cDNA FLJ55293, highly similar to Heat shock 70 kDa protein 4 OS=Homo sapiens PE=2 SV=1 YBR169c 456 6.00E-128 COG0443 Molecular chaperone O Posttranslational modification, protein turnover, chaperones ; K09489|1|0.0|1627|hsa:3308|heat shock 70kDa protein 4 GO:0009408//response to heat;GO:0045040//protein import into mitochondrial outer membrane;GO:0032092//positive regulation of protein binding;GO:0006986//response to unfolded protein;GO:0051131//chaperone-mediated protein complex assembly GO:0005524//ATP binding GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005811//lipid particle 306 tr|B2R7Y0|B2R7Y0_HUMAN cDNA, FLJ93654, highly similar to Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 2 (SERPINB2), mRNA OS=Homo sapiens PE=2 SV=1 55688 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGDYLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITKCILFFGRFSSP 155 8.4 1 6 6 3 3 0.559 0.354 0.398 3 3 3 - * - 0.437 0.107921268 tr|B2R7Y0|B2R7Y0_HUMAN 100 0 gi|189053725|dbj|BAG35977.1| unnamed protein product [Homo sapiens] 99.52 0 sp|P05120|PAI2_HUMAN Plasminogen activator inhibitor 2 OS=Homo sapiens GN=SERPINB2 PE=1 SV=2 100 0 B2R7Y0 B2R7Y0_HUMAN cDNA, FLJ93654, highly similar to Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 2 (SERPINB2), mRNA OS=Homo sapiens PE=2 SV=1 MA2246 222 1.00E-57 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K13963|1|0.0|810|hsa:5055|serpin B GO:0042730//fibrinolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis GO:0004867//serine-type endopeptidase inhibitor activity GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane 307 tr|Q0PHS1|Q0PHS1_HUMAN Glucose-6-phosphate 1-dehydrogenase (Fragment) OS=Homo sapiens GN=G6PD PE=3 SV=1 38422 WLFRDGLLPENTFIMGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKMLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWD 85 14.8 9 6 6 4 4 1.687 0.934 1.378 2 2 2 - - - 1.333 0.378511559 tr|Q0PHS1|Q0PHS1_HUMAN 100 2.00E-177 gi|111052659|gb|ABH03569.1| glucose-6-phosphate dehydrogenase [Homo sapiens] 99.33 6.00E-177 sp|P11413|G6PD_HUMAN Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens GN=G6PD PE=1 SV=4 100 6.00E-177 Q0PHS1 Q0PHS1_HUMAN Glucose-6-phosphate 1-dehydrogenase (Fragment) OS=Homo sapiens GN=G6PD PE=2 SV=1 YNL241c 287 1.00E-77 COG0364 Glucose-6-phosphate 1-dehydrogenase G Carbohydrate transport and metabolism ; K00036|1|1e-176|619|hsa:2539|glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49] GO:0010734//negative regulation of protein glutathionylation;GO:0043249//erythrocyte maturation;GO:0051156//glucose 6-phosphate metabolic process;GO:0019322//pentose biosynthetic process;GO:0046390//ribose phosphate biosynthetic process;GO:0001816//cytokine production;GO:0009051//pentose-phosphate shunt, oxidative branch;GO:0006695//cholesterol biosynthetic process;GO:0006749//glutathione metabolic process;GO:0034599//cellular response to oxidative stress GO:0050661//NADP binding;GO:0004345//glucose-6-phosphate dehydrogenase activity;GO:0005536//glucose binding;GO:0042803//protein homodimerization activity GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005813//centrosome;GO:0009898//internal side of plasma membrane 308 tr|Q7Z759|Q7Z759_HUMAN CCT8 protein OS=Homo sapiens GN=CCT8 PE=2 SV=1 66145 MNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKAHEILPNLVCCSAKNLRDIDEVSSLLRTSIMSKQYGNEVFLAKLIAQACVSIFPDSGHFNVDNIRVCKILGSGISSSSVLHGMVFKKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKDWDDDQND 158 10.7 2 6 6 4 4 0.783 0.528 0.413 4 4 3 - * * 0.574666667 0.189362967 tr|Q7Z759|Q7Z759_HUMAN 100 0 gi|31418053|gb|AAH12584.1| CCT8 protein [Homo sapiens] >gi|119630331|gb|EAX09926.1| chaperonin containing TCP1, subunit 8 (theta), isoform CRA_c [Homo sapiens] 100 0 sp|Q5RAP1|TCPQ_PONAB T-complex protein 1 subunit theta OS=Pongo abelii GN=CCT8 PE=2 SV=3 100 0 G3QU21 G3QU21_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=CCT8 PE=3 SV=1 YJL008c 463 3.00E-130 COG0459 Chaperonin GroEL (HSP60 family) O Posttranslational modification, protein turnover, chaperones ; K09500|1|0.0|918|pon:100172606|T-complex protein 1 subunit theta GO:0051084//'de novo' posttranslational protein folding GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0042623//ATPase activity, coupled GO:0045111//intermediate filament cytoskeleton;GO:0016235//aggresome;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005874//microtubule 309 tr|A8K4Z4|A8K4Z4_HUMAN cDNA FLJ75549, highly similar to Homo sapiens ribosomal protein, large, P0 (RPLP0), transcript variant 1, mRNA OS=Homo sapiens PE=2 SV=1 40473 MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCEVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNMLNISPLSFGLVIQQVFDNGSIYNPEVLDITEETLHSRFLEGVRNVASVCLQIGYPTVASVPHSIINGYKRVLALSVETDYTFPLAEKVKAFLADPSAFVAAAPVAAATTAAPAAAAAPAKVEAKEESEESDEDMGFGLFD 380 30.6 2 19 19 6 6 1.227 1.234 1.561 14 14 13 - - * 1.340666667 0.190846361 tr|A8K4Z4|A8K4Z4_HUMAN 100 1.00E-80 gi|402887849|ref|XP_003907293.1| PREDICTED: 60S acidic ribosomal protein P0 isoform 3 [Papio anubis] 99.63 4.00E-150 sp|P05388|RLA0_HUMAN 60S acidic ribosomal protein P0 OS=Homo sapiens GN=RPLP0 PE=1 SV=1 100 4.00E-149 A8K4Z4 A8K4Z4_HUMAN cDNA FLJ75549, highly similar to Homo sapiens ribosomal protein, large, P0 (RPLP0), transcript variant 1, mRNA OS=Homo sapiens PE=2 SV=1 SPCC18.14c 316 3.00E-86 COG0244 Ribosomal protein L10 J Translation, ribosomal structure and biogenesis ; K02941|1|4e-150|531|bta:286868|large subunit ribosomal protein LP0 GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006414//translational elongation;GO:0042254//ribosome biogenesis;GO:0006415//translational termination;GO:0019048//virus-host interaction;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding GO:0022625//cytosolic large ribosomal subunit;GO:0005634//nucleus 310 sp|Q8WUJ3|CEMIP_HUMAN Cell migration-inducing and hyaluronan-binding protein OS=Homo sapiens GN=CEMIP PE=1 SV=2 180297 MGAAGRQDFLFKAMLTISWLTLTCFPGATSTVAAGCPDQSPELQPWNPGHDQDHHVHIGQGKTLLLTSSATVYSIHISEGGKLVIKDHDEPIVLRTRHILIDNGGELHAGSALCPFQGNFTIILYGRADEGIQPDPYYGLKYIGVGKGGALELHGQKKLSWTFLNKTLHPGGMAEGGYFFERSWGHRGVIVHVIDPKSGTVIHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDEGSRNLDDMARKAMTKLGSKHFLHLGFRHPWSFLTVKGNPSSSVEDHIEYHGHRGSAAARVFKLFQTEHGEYFNVSLSSEWVQDVEWTEWFDHDKVSQTKGGEKISDLWKAHPGKICNRPIDIQATTMDGVNLSTEVVYKKGQDYRFACYDRGRACRSYRVRFLCGKPVRPKLTVTIDTNVNSTILNLEDNVQSWKPGDTLVIASTDYSMYQAEEFQVLPCRSCAPNQVKVAGKPMYLHIGEEIDGVDMRAEVGLLSRNIIVMGEMEDKCYPYRNHICNFFDFDTFGGHIKFALGFKAAHLEGTELKHMGQQLVGQYPIHFHLAGDVDERGGYDPPTYIRDLSIHHTFSRCVTVHGSNGLLIKDVVGYNSLGHCFFTEDGPEERNTFDHCLGLLVKSGTLLPSDRDSKMCKMITEDSYPGYIPKPRQDCNAVSTFWMANPNNNLINCAAAGSEETGFWFIFHHVPTGPSVGMYSPGYSEHIPLGKFYNNRAHSNYRAGMIIDNGVKTTEASAKDKRPFLSIISARYSPHQDADPLKPREPAIIRHFIAYKNQDHGAWLRGGDVWLDSCRFADNGIGLTLASGGTFPYDDGSKQEIKNSLFVGESGNVGTEMMDNRIWGPGGLDHSGRTLPIGQNFPIRGIQLYDGPINIQNCTFRKFVALEGRHTSALAFRLNNAWQSCPHNNVTGIAFEDVPITSRVFFGEPGPWFNQLDMDGDKTSVFHDVDGSVSEYPGSYLTKNDNWLVRHPDCINVPDWRGAICSGCYAQMYIQAYKTSNLRMKIIKNDFPSHPLYLEGALTRSTHYQQYQPVVTLQKGYTIHWDQTAPAELAIWLINFNKGDWIRVGLCYPRGTTFSILSDVHNRLLKQTSKTGVFVRTLQMDKVEQSYPGRSHYYWDEDSGLLFLKLKAQNEREKFAFCSMKGCERIKIKALIPKNAGVSDCTATAYPKFTERAVVDVPMPKKLFGSQLKTKDHFLEVKMESSKQHFFHLWNDFAYIEVDGKKYPSSEDGIQVVVIDGNQGRVVSHTSFRNSILQGIPWQLFNYVATIPDNSIVLMASKGRYVSRGPWTRVLEKLGADRGLKLKEQMAFVGFKGSFRPIWVTLDTEDHKAKIFQVVPIPVVKKKKL 74 5.7 - 7 7 6 6 1.349 1.009 0.791 4 4 4 - - - 1.049666667 0.281214035 sp|Q8WUJ3|CEMIP_HUMAN 100 0 gi|8518188|emb|CAB94391.1| KIAA1199 hypothetical protein [Homo sapiens] 100 0 sp|Q8WUJ3|K1199_HUMAN Protein KIAA1199 OS=Homo sapiens GN=KIAA1199 PE=1 SV=2 100 0 C9JCC4 C9JCC4_HUMAN Protein KIAA1199 OS=Homo sapiens GN=KIAA1199 PE=4 SV=1 - - - - - - - K09666|1|9e-11|70.5|cbr:CBG13870|beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.-] - - GO:0005737//cytoplasm 311 tr|A0A024RAF2|A0A024RAF2_HUMAN Diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein), isoform CRA_a OS=Homo sapiens GN=DBI PE=4 SV=1 16045 MWGDLWLLPPASANPGTGTEAEFEKAAEEVRHLKTKPSDEEMLFIYGHYKQATVGDINTERPGMLDFTGKAKWDAWNELKGTSKEDAMKAYINKVEELKKKYGI 68 26.9 5 5 5 2 2 0.842 0.844 0.938 2 2 2 - - - 0.874666667 0.054857391 tr|A0A024RAF2|A0A024RAF2_HUMAN 100 7.00E-43 gi|295849266|ref|NP_001171488.1| acyl-CoA-binding protein isoform 4 [Homo sapiens] >gi|219966107|emb|CAR82409.1| diazepam binding inhibitor, splice form 1G [Homo sapiens] 97.67 2.00E-43 sp|P07108|ACBP_HUMAN Acyl-CoA-binding protein OS=Homo sapiens GN=DBI PE=1 SV=2 100 5.00E-54 B8ZWD2 B8ZWD2_HUMAN Diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein), isoform CRA_a OS=Homo sapiens GN=DBI PE=4 SV=1 SPBC1539.06 102 1.00E-22 COG4281 Acyl-CoA-binding protein I Lipid transport and metabolism ; K08762|1|1e-53|207|ptr:459574|diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein) GO:0006641//triglyceride metabolic process;GO:0043588//skin development;GO:0006810//transport;GO:0001942//hair follicle development GO:0000062//fatty-acyl-CoA binding;GO:0008289//lipid binding;GO:0030156//benzodiazepine receptor binding GO:0005794//Golgi apparatus;GO:0005778//peroxisomal membrane;GO:0016021//integral to membrane;GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion 312 tr|B2MV14|B2MV14_HUMAN Truncated lactoferrin OS=Homo sapiens GN=LTF PE=3 SV=1 75410 MKLVFLVLLFLGALGLCLAGRRRRSVQWCTVSQPEATKCFQWQRNMRRVRGPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGGSFQLNELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCVPGADKGQFPNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGFSRVPPRIDSGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWSGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQTGSCKFDEYFSQSCAPGSDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNMRHGLRI 509 3.6 11 25 25 2 2 0.694 0.605 0.688 14 14 14 * * * 0.662333333 0.049742671 tr|B2MV14|B2MV14_HUMAN 100 0 gi|28948741|pdb|1N76|A Chain A, Crystal Structure Of Human Seminal Lactoferrin At 3.4 A Resolution 99.64 0 sp|P02788|TRFL_HUMAN Lactotransferrin OS=Homo sapiens GN=LTF PE=1 SV=6 100 0 B2MV13 B2MV13_HUMAN Lactoferrin OS=Homo sapiens GN=LTF PE=4 SV=1 - - - - - - - K14736|1|0.0|713|bta:280705|transferrin GO:0042742//defense response to bacterium;GO:0090382//phagosome maturation;GO:0006508//proteolysis;GO:0033214//iron assimilation by chelation and transport;GO:0006959//humoral immune response;GO:0006826//iron ion transport;GO:0052572//response to host immune response GO:0008199//ferric iron binding;GO:0005515//protein binding;GO:0004252//serine-type endopeptidase activity;GO:0008201//heparin binding GO:0030141//secretory granule;GO:0097013//phagocytic vesicle lumen;GO:0005576//extracellular region 313 tr|A0A090N8G0|A0A090N8G0_HUMAN Glycyl-tRNA synthetase OS=Homo sapiens GN=GARS PE=4 SV=1 94288 MDGAGAEEVLAPLRLAVRQQGDLVRKLKEDKAPQVDVDKAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSVEKKSEMESVLAQLDNYGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMAHYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTIETEGKTFQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETGKKETIEE 99 6.6 1 6 6 4 4 1.097 0.737 0.617 2 2 2 - - - 0.817 0.24979992 tr|A0A090N8G0|A0A090N8G0_HUMAN 100 0 gi|600727|gb|AAA57001.1| glycyl-tRNA synthetase [Homo sapiens] >gi|51105865|gb|EAL24449.1| glycyl-tRNA synthetase [Homo sapiens] 100 0 sp|P41250|SYG_HUMAN Glycine--tRNA ligase OS=Homo sapiens GN=GARS PE=1 SV=3 100 0 G3QQF1 G3QQF1_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=GARS PE=3 SV=1 SPAC3F10.03 632 0 COG0423 Glycyl-tRNA synthetase (class II) J Translation, ribosomal structure and biogenesis ; K01880|1|0.0|1430|hsa:2617|glycyl-tRNA synthetase [EC:6.1.1.14] GO:0008219//cell death;GO:0006426//glycyl-tRNA aminoacylation;GO:0015966//diadenosine tetraphosphate biosynthetic process GO:0005524//ATP binding;GO:0046983//protein dimerization activity;GO:0004820//glycine-tRNA ligase activity GO:0005829//cytosol;GO:0030141//secretory granule;GO:0005759//mitochondrial matrix 314 tr|H0YL18|H0YL18_HUMAN Beta-2-microglobulin OS=Homo sapiens GN=B2M PE=1 SV=1 17119 MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWGKSYILL 62 8.2 6 2 2 1 1 0.901 0.684 1.188 2 2 2 - - * 0.924333333 0.252808887 tr|H0YL18|H0YL18_HUMAN 100 2.00E-51 gi|340780629|pdb|3S6C|A Chain A, Structure Of Human Cd1e 98.29 5.00E-55 sp|P61769|B2MG_HUMAN Beta-2-microglobulin OS=Homo sapiens GN=B2M PE=1 SV=1 100 4.00E-57 G3RQY0 G3RQY0_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla PE=3 SV=1 - - - - - - - K08055|1|5e-55|212|pon:100174579|beta-2-microglobulin GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0016032//viral reproduction;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0050690//regulation of defense response to virus by virus;GO:0033077//T cell differentiation in thymus;GO:0042493//response to drug;GO:0046686//response to cadmium ion;GO:0042026//protein refolding;GO:0002237//response to molecule of bacterial origin;GO:0002481//antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent GO:0005515//protein binding GO:0042612//MHC class I protein complex;GO:0030670//phagocytic vesicle membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0000139//Golgi membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0031905//early endosome lumen;GO:0009897//external side of plasma membrane;GO:0031901//early endosome membrane 315 tr|A0A024RBE6|A0A024RBE6_HUMAN Nucleosome assembly protein 1-like 1, isoform CRA_b OS=Homo sapiens GN=NAP1L1 PE=3 SV=1 51244 MMQNPQILAALQERLDGLVETPTGYIESLPRVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEPTEEECEWKPDEEDEISEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNEYFTNEVLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPESGDLDDDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEEADEEGEEEGDEENDPDYDPKKDQNPAECKQQ 63 6 15 3 3 2 2 1.299 0.744 1.587 2 2 2 - - - 1.21 0.428489206 tr|A0A024RBE6|A0A024RBE6_HUMAN 100 1.00E-108 gi|193786167|dbj|BAG51450.1| unnamed protein product [Homo sapiens] 100 1.00E-112 sp|P55209|NP1L1_HUMAN Nucleosome assembly protein 1-like 1 OS=Homo sapiens GN=NAP1L1 PE=1 SV=1 100 2.00E-41 B7Z5H0 B7Z5H0_HUMAN cDNA FLJ54129, highly similar to Nucleosome assembly protein 1-like 1 OS=Homo sapiens PE=2 SV=1 - - - - - - - K11279|1|6e-113|407|ecb:100050241|nucleosome assembly protein 1-like 1 GO:0006260//DNA replication;GO:0008284//positive regulation of cell proliferation GO:0005515//protein binding - 316 sp|P28072|PSB6_HUMAN Proteasome subunit beta type-6 OS=Homo sapiens GN=PSMB6 PE=1 SV=4 >tr|Q6IAT9|Q6IAT9_HUMAN Proteasome subunit beta type OS=Homo sapiens GN=PSMB6 PE=2 SV=1 27091 MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA 65 4.2 - 2 2 1 1 0.879 0.689 0.619 2 2 2 - - - 0.729 0.13453624 sp|P28072|PSB6_HUMAN 100 9.00E-109 gi|23110925|ref|NP_002789.1| proteasome subunit beta type-6 isoform 1 proprotein [Homo sapiens] >gi|20532407|sp|P28072.4|PSB6_HUMAN RecName: Full=Proteasome subunit beta type-6; AltName: Full=Macropain delta chain; AltName: Full=Multicatalytic endopeptidase complex delta chain; AltName: Full=Proteasome delta chain; AltName: Full=Proteasome subunit Y; Flags: Precursor >gi|12654059|gb|AAH00835.1| Proteasome (prosome, macropain) subunit, beta type, 6 [Homo sapiens] >gi|32879961|gb|AAP88811.1| proteasome (prosome, macropain) subunit, beta type, 6 [Homo sapiens] >gi|48146247|emb|CAG33346.1| PSMB6 [Homo sapiens] >gi|119610813|gb|EAW90407.1| proteasome (prosome, macropain) subunit, beta type, 6 [Homo sapiens] 100 1.00E-109 sp|P28072|PSB6_HUMAN Proteasome subunit beta type-6 OS=Homo sapiens GN=PSMB6 PE=1 SV=4 100 3.00E-108 Q6IAT9 Q6IAT9_HUMAN Proteasome subunit beta type OS=Homo sapiens GN=PSMB6 PE=2 SV=1 MJ1237 106 3.00E-23 COG0638 20S proteasome, alpha and beta subunits O Posttranslational modification, protein turnover, chaperones ; K02738|1|1e-109|395|hsa:5694|20S proteasome subunit beta 1 [EC:3.4.25.1] GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0019048//virus-host interaction;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0004298//threonine-type endopeptidase activity GO:0005654//nucleoplasm;GO:0005839//proteasome core complex;GO:0005829//cytosol 317 tr|A0A0A0MT32|A0A0A0MT32_HUMAN Lysosomal acid lipase/cholesteryl ester hydrolase OS=Homo sapiens GN=LIPA PE=4 SV=1 38310 MGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ 159 9.5 6 12 12 3 3 1.623 1.199 1.776 8 8 7 * - * 1.532666667 0.298918607 tr|A0A0A0MT32|A0A0A0MT32_HUMAN 100 1.00E-158 gi|505053|gb|AAB60328.1| lysosomal acid lipase [Homo sapiens] >gi|506431|emb|CAA83495.1| lysosomal acid lipase [Homo sapiens] 100 1.00E-159 sp|P38571|LICH_HUMAN Lysosomal acid lipase/cholesteryl ester hydrolase OS=Homo sapiens GN=LIPA PE=1 SV=2 100 3.00E-158 G3QN03 G3QN03_GORGO Lipase OS=Gorilla gorilla gorilla GN=LIPA PE=3 SV=1 SPBC16A3.12c 134 1.00E-31 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) R General function prediction only ; K01052|1|1e-159|562|hsa:3988|lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] GO:0030324//lung development;GO:0006631//fatty acid metabolic process;GO:0048873//homeostasis of number of cells within a tissue;GO:0006954//inflammatory response;GO:0016042//lipid catabolic process;GO:0048771//tissue remodeling;GO:0000902//cell morphogenesis;GO:0016125//sterol metabolic process;GO:0008283//cell proliferation;GO:0001816//cytokine production GO:0016298//lipase activity;GO:0004771//sterol esterase activity GO:0005764//lysosome 318 tr|A0A087WV23|A0A087WV23_HUMAN SH3 domain-binding glutamic acid-rich-like protein 3 OS=Homo sapiens GN=SH3BGRL3 PE=1 SV=1 26186 MHQTCVRLEREASARPSPGPVLPPRPLPSHTELQIREGPKRTIRAAAEGAPCVGRVRCAPGNRGGREGASGVRGGVAQVPPRLPAPPIGPERDDLAGGAGRKPLPSTAAASSPGSAAAATAALCPPARLSTPSMSGLRVYSTSVTGSREIKSQQSEVTRILDGKRIQYQLVDISQDNALRDEMRALAGNPKATPPQIVNGDQYCGDYELFVEAVEQNTLQEFLKLA 278 8.4 4 18 18 2 2 0.483 0.564 0.541 13 15 15 - * * 0.529333333 0.041741267 tr|A0A087WV23|A0A087WV23_HUMAN 100 5.00E-38 gi|444706308|gb|ELW47651.1| SH3 domain-binding glutamic acid-rich-like protein 3 [Tupaia chinensis] 100 1.00E-48 sp|Q9H299|SH3L3_HUMAN SH3 domain-binding glutamic acid-rich-like protein 3 OS=Homo sapiens GN=SH3BGRL3 PE=1 SV=1 100 3.00E-47 G5AUR1 G5AUR1_HETGA SH3 domain-binding glutamic acid-rich-like protein 3 OS=Heterocephalus glaber GN=GW7_08411 PE=4 SV=1 - - - - - - - K01047|1|5e-09|61.6|nve:NEMVE_v1g199410|phospholipase A2 [EC:3.1.1.4] GO:0045454//cell redox homeostasis;GO:0055114//oxidation-reduction process GO:0009055//electron carrier activity;GO:0015035//protein disulfide oxidoreductase activity GO:0005737//cytoplasm;GO:0005634//nucleus 319 tr|B2R6V9|B2R6V9_HUMAN cDNA, FLJ93141, highly similar to Homo sapiens coagulation factor XIII, A1 polypeptide (F13A1), mRNA OS=Homo sapiens PE=2 SV=1 95566 MSETSRTAFGGRRAVPPNNSNAAEDDLPTVELQGVVPRGVSLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQIQRRPSM 152 2.2 4 6 6 1 1 0.69 0.907 0.941 4 3 3 - - - 0.846 0.136165341 tr|B2R6V9|B2R6V9_HUMAN 100 0 gi|189053440|dbj|BAG35606.1| unnamed protein product [Homo sapiens] 99.73 0 sp|P00488|F13A_HUMAN Coagulation factor XIII A chain OS=Homo sapiens GN=F13A1 PE=1 SV=4 100 0 B2R6V9 B2R6V9_HUMAN cDNA, FLJ93141, highly similar to Homo sapiens coagulation factor XIII, A1 polypeptide (F13A1), mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K03917|1|0.0|1527|hsa:2162|coagulation factor XIII A1 polypeptide [EC:2.3.2.13] GO:0018149//peptide cross-linking;GO:0030168//platelet activation;GO:0002576//platelet degranulation GO:0046872//metal ion binding;GO:0003810//protein-glutamine gamma-glutamyltransferase activity GO:0031093//platelet alpha granule lumen;GO:0005576//extracellular region 320 sp|A1L4H1|SRCRL_HUMAN Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D OS=Homo sapiens GN=SSC5D PE=2 SV=3 178434 MRVLACLLAALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPRLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLDSISDPFSWSWIPGLGRDRDAWLPGELATKPSASVTASVLEKTTTKAPGKMPKSTKKWVTKNAKRPTTQPPVMPTTKHSRAQSPPDLTSQTTAALTTEASRRPTSEFTRRPTTEAPQRWTSHTTATLTPQAPRERTTKTMAMLTTQGPQEMTSESTIKSIPQASLEPSAEIPEGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYDDYPPWTWDPTSREDLAKGTTTAGVPGHTLPWRTTRRPGSSSPAIRRLPDTGSKDGYKLPWTWDTPSGRGLAEGTPTAGKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPHGPCVAPTPPVRVMACEPPALVELVAAVRDVGGQLQRLTQVVEQERQERQALLLGLTQLVEAARGLGQLGEAVKRLAEMAWTTSMPAPTTTTPEEEERPLRGDV 289 3.9 - 15 15 5 5 0.839 1.127 1.226 12 11 11 - - - 1.064 0.201044771 sp|A1L4H1|SRCRL_HUMAN 100 2.00E-34 gi|119592793|gb|EAW72387.1| hCG38650 [Homo sapiens] 100 1.00E-66 sp|A1L4H1|SRCRL_HUMAN Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D OS=Homo sapiens GN=SSC5D PE=2 SV=3 99.36 0 F5GZN4 F5GZN4_HUMAN Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D OS=Homo sapiens GN=SSC5D PE=4 SV=1 - - - - - - - K13912|1|2e-114|415|ptr:466221|deleted in malignant brain tumors 1 protein - GO:0005044//scavenger receptor activity GO:0016020//membrane;GO:0005576//extracellular region 321 sp|P46939|UTRO_HUMAN Utrophin OS=Homo sapiens GN=UTRN PE=1 SV=2 476754 MAKYGEHEASPDNGQNEFSDIIKSRSDEHNDVQKKTFTKWINARFSKSGKPPINDMFTDLKDGRKLLDLLEGLTGTSLPKERGSTRVHALNNVNRVLQVLHQNNVELVNIGGTDIVDGNHKLTLGLLWSIILHWQVKDVMKDVMSDLQQTNSEKILLSWVRQTTRPYSQVNVLNFTTSWTDGLAFNAVLHRHKPDLFSWDKVVKMSPIERLEHAFSKAQTYLGIEKLLDPEDVAVQLPDKKSIIMYLTSLFEVLPQQVTIDAIREVETLPRKYKKECEEEAINIQSTAPEEEHESPRAETPSTVTEVDMDLDSYQIALEEVLTWLLSAEDTFQEQDDISDDVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGNQLITQGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLHDVLMELQKKQLQQLSAWLTLTEERIQKMETCPLDDDVKSLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVDENSGESATAILEDQLQKLGERWTAVCRWTEERWNRLQEINILWQELLEEQCLLKAWLTEKEEALNKVQTSNFKDQKELSVSVRRLAILKEDMEMKRQTLDQLSEIGQDVGQLLDNSKASKKINSDSEELTQRWDSLVQRLEDSSNQVTQAVAKLGMSQIPQKDLLETVRVREQAITKKSKQELPPPPPPKKRQIHVDIEAKKKFDAISAELLNWILKWKTAIQTTEIKEYMKMQDTSEMKKKLKALEKEQRERIPRADELNQTGQILVEQMGKEGLPTEEIKNVLEKVSSEWKNVSQHLEDLERKIQLQEDINAYFKQLDELEKVIKTKEEWVKHTSISESSRQSLPSLKDSCQRELTNLLGLHPKIEMARASCSALMSQPSAPDFVQRGFDSFLGRYQAVQEAVEDRQQHLENELKGQPGHAYLETLKTLKDVLNDSENKAQVSLNVLNDLAKVEKALQEKKTLDEILENQKPALHKLAEETKALEKNVHPDVEKLYKQEFDDVQGKWNKLKVLVSKDLHLLEEIALTLRAFEADSTVIEKWMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAFVNEIETIESSLKNMKEIETNLRSGPVAGIKTWVQTRLGDYQTQLEKLSKEIATQKSRLSESQEKAANLKKDLAEMQEWMTQAEEEYLERDFEYKSPEELESAVEEMKRAKEDVLQKEVRVKILKDNIKLLAAKVPSGGQELTSELNVVLENYQLLCNRIRGKCHTLEEVWSCWIELLHYLDLETTWLNTLEERMKSTEVLPEKTDAVNEALESLESVLRHPADNRTQIRELGQTLIDGGILDDIISEKLEAFNSRYEDLSHLAESKQISLEKQLQVLRETDQMLQVLQESLGELDKQLTTYLTDRIDAFQVPQEAQKIQAEISAHELTLEELRRNMRSQPLTSPESRTARGGSQMDVLQRKLREVSTKFQLFQKPANFEQRMLDCKRVLDGVKAELHVLDVKDVDPDVIQTHLDKCMKLYKTLSEVKLEVETVIKTGRHIVQKQQTDNPKGMDEQLTSLKVLYNDLGAQVTEGKQDLERASQLARKMKKEAASLSEWLSATETELVQKSTSEGLLGDLDTEISWAKNVLKDLEKRKADLNTITESSAALQNLIEGSEPILEERLCVLNAGWSRVRTWTEDWCNTLMNHQNQLEIFDGNVAHISTWLYQAEALLDEIEKKPTSKQEEIVKRLVSELDDANLQVENVRDQALILMNARGSSSRELVEPKLAELNRNFEKVSQHIKSAKLLIAQEPLYQCLVTTETFETGVPFSDLEKLENDIENMLKFVEKHLESSDEDEKMDEESAQIEEVLQRGEEMLHQPMEDNKKEKIRLQLLLLHTRYNKIKAIPIQQRKMGQLASGIRSSLLPTDYLVEINKILLCMDDVELSLNVPELNTAIYEDFSFQEDSLKNIKDQLDKLGEQIAVIHEKQPDVILEASGPEAIQIRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAEELLVDTCAPGGSLDLEKARIHQQELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFLKEKLAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICWLTKAEHAMQKRSTTELGENLQELRDLTQEMEVHAEKLKWLNRTELEMLSDKSLSLPERDKISESLRTVNMTWNKICREVPTTLKECIQEPSSVSQTRIAAHPNVQKVVLVSSASDIPVQSHRTSEISIPADLDKTITELADWLVLIDQMLKSNIVTVGDVEEINKTVSRMKITKADLEQRHPQLDYVFTLAQNLKNKASSSDMRTAITEKLERVKNQWDGTQHGVELRQQQLEDMIIDSLQWDDHREETEELMRKYEARLYILQQARRDPLTKQISDNQILLQELGPGDGIVMAFDNVLQKLLEEYGSDDTRNVKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQEAETTVNVLVDASHRENALQDSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHRLDDMNQRWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGGDVPALQLQYDHCKALRRELKEKEYSVLNAVDQARVFLADQPIEAPEEPRRNLQSKTELTPEERAQKIAKAMRKQSSEVKEKWESLNAVTSNWQKQVDKALEKLRDLQGAMDDLDADMKEAESVRNGWKPVGDLLIDSLQDHIEKIMAFREEIAPINFKVKTVNDLSSQLSPLDLHPSLKMSRQLDDLNMRWKLLQVSVDDRLKQLQEAHRDFGPSSQHFLSTSVQLPWQRSISHNKVPYYINHQTQTTCWDHPKMTELFQSLADLNNVRFSAYRTAIKIRRLQKALCLDLLELSTTNEIFKQHKLNQNDQLLSVPDVINCLTTTYDGLEQMHKDLVNVPLCVDMCLNWLLNVYDTGRTGKIRVQSLKIGLMSLSKGLLEEKYRYLFKEVAGPTEMCDQRQLGLLLHDAIQIPRQLGEVAAFGGSNIEPSVRSCFQQNNNKPEISVKEFIDWMHLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIVGFRYRSLKHFNYDVCQSCFFSGRTAKGHKLHYPMVEYCIPTTSGEDVRDFTKVLKNKFRSKKYFAKHPRLGYLPVQTVLEGDNLETPITLISMWPEHYDPSQSPQLFHDDTHSRIEQYATRLAQMERTNGSFLTDSSSTTGSVEDEHALIQQYCQTLGGESPVSQPQSPAQILKSVEREERGELERIIADLEEEQRNLQVEYEQLKDQHLRRGLPVGSPPESIISPHHTSEDSELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPESDSRINGVSPWASPQHSALSYSLDPDASGPQFHQAAGEDLLAPPHDTSTDLTEVMEQIHSTFPSCCPNVPSRPQAM 66 1.2 - 4 4 4 4 --- 0.035 0.945 1 2 2 - - - 0.49 0.643467171 sp|P46939|UTRO_HUMAN 100 0 gi|930062|emb|CAA33515.1| dystrophin-related protein (490 AA) [Homo sapiens] 100 0 sp|P46939|UTRO_HUMAN Utrophin OS=Homo sapiens GN=UTRN PE=1 SV=2 100 0 Q6LBS5 Q6LBS5_HUMAN Dystrophin-related protein (490 AA) (Fragment) OS=Homo sapiens PE=2 SV=1 ECU09g0290 170 5.00E-41 COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) Z Cytoskeleton ; K10366|1|0.0|1578|gga:396236|dystrophin GO:0001954//positive regulation of cell-matrix adhesion;GO:0007517//muscle organ development;GO:0006936//muscle contraction GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0003779//actin binding GO:0030054//cell junction;GO:0043234//protein complex;GO:0005856//cytoskeleton;GO:0005730//nucleolus;GO:0045211//postsynaptic membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane 322 tr|Q9UNM1|Q9UNM1_HUMAN Chaperonin 10-related protein (Fragment) OS=Homo sapiens GN=EPFP1 PE=3 SV=1 13635 AGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTKVVLDDKDYFLFRDGDILG 147 45.4 1 12 12 4 4 0.704 0.939 0.655 7 7 6 * - * 0.766 0.151812384 tr|Q9UNM1|Q9UNM1_HUMAN 100 3.00E-41 gi|297300735|ref|XP_002805650.1| PREDICTED: 10 kDa heat shock protein, mitochondrial-like isoform 2 [Macaca mulatta] 100 5.00E-42 sp|P61604|CH10_HUMAN 10 kDa heat shock protein, mitochondrial OS=Homo sapiens GN=HSPE1 PE=1 SV=2 100 2.00E-40 F7BG90 F7BG90_MACMU 10 kDa heat shock protein, mitochondrial OS=Macaca mulatta GN=LOC720015 PE=3 SV=1 SPCC550.06c 85.5 2.00E-17 COG0234 Co-chaperonin GroES (HSP10) O Posttranslational modification, protein turnover, chaperones ; K04078|1|7e-43|171|ecb:100629260|chaperonin GroES GO:0006457//protein folding;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006986//response to unfolded protein GO:0051087//chaperone binding;GO:0005524//ATP binding;GO:0051082//unfolded protein binding GO:0005759//mitochondrial matrix 323 tr|B4DVA7|B4DVA7_HUMAN Beta-hexosaminidase OS=Homo sapiens PE=2 SV=1 68514 MTSSRLWFSLLLAAAFAGRATALWPWPQNFQTSDQRYVLYPNNFRFQYDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRPYLTGWPHQAYPVFLGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELLRRGVQAQPLNVGFCEQEFEQT 868 19.6 1 44 44 8 8 1.309 1.084 1.314 31 32 32 * - * 1.235666667 0.131370976 tr|B4DVA7|B4DVA7_HUMAN 100 0 gi|33876034|gb|AAH01138.2| HEXA protein, partial [Homo sapiens] 97.48 0 sp|P06865|HEXA_HUMAN Beta-hexosaminidase subunit alpha OS=Homo sapiens GN=HEXA PE=1 SV=2 100 0 B4DVA7 B4DVA7_HUMAN cDNA FLJ53927, highly similar to Beta-hexosaminidase alpha chain (EC 3.2.1.52) OS=Homo sapiens PE=2 SV=1 CC0447 177 5.00E-44 COG3525 N-acetyl-beta-hexosaminidase G Carbohydrate transport and metabolism ; K12373|1|0.0|1035|hsa:3073|hexosaminidase [EC:3.2.1.52] GO:0001501//skeletal system development;GO:0030207//chondroitin sulfate catabolic process;GO:0006689//ganglioside catabolic process;GO:0007605//sensory perception of sound;GO:0007040//lysosome organization;GO:0019953//sexual reproduction;GO:0050884//neuromuscular process controlling posture;GO:0007628//adult walking behavior;GO:0030214//hyaluronan catabolic process;GO:0019915//lipid storage;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0008219//cell death;GO:0050885//neuromuscular process controlling balance;GO:0042340//keratan sulfate catabolic process;GO:0042552//myelination;GO:0006644//phospholipid metabolic process GO:0004563//beta-N-acetylhexosaminidase activity;GO:0046982//protein heterodimerization activity;GO:0043169//cation binding GO:0016020//membrane;GO:0043202//lysosomal lumen 324 sp|P08758|ANXA5_HUMAN Annexin A5 OS=Homo sapiens GN=ANXA5 PE=1 SV=2 >tr|V9HWE0|V9HWE0_HUMAN Annexin OS=Homo sapiens GN=HEL-S-7 PE=2 SV=1 42968 MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD 307 24.4 - 25 25 8 8 0.885 0.754 1.448 7 9 7 - - - 1.029 0.368728898 sp|P08758|ANXA5_HUMAN 100 0 gi|809185|pdb|1ANW|A Chain A, The Effect Of Metal Binding On The Structure Of Annexin V And Implications For Membrane Binding >gi|809186|pdb|1ANW|B Chain B, The Effect Of Metal Binding On The Structure Of Annexin V And Implications For Membrane Binding >gi|809188|pdb|1ANX|A Chain A, The Crystal Structure Of A New High-Calcium Form Of Annexin V >gi|809189|pdb|1ANX|B Chain B, The Crystal Structure Of A New High-Calcium Form Of Annexin V >gi|809190|pdb|1ANX|C Chain C, The Crystal Structure Of A New High-Calcium Form Of Annexin V 100 0 sp|P08758|ANXA5_HUMAN Annexin A5 OS=Homo sapiens GN=ANXA5 PE=1 SV=2 100 4.00E-106 D6RBE9 D6RBE9_HUMAN Annexin OS=Homo sapiens GN=ANXA5 PE=3 SV=1 - - - - - - - - GO:0050819//negative regulation of coagulation;GO:0051260//protein homooligomerization;GO:0043065//positive regulation of apoptotic process;GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:0010033//response to organic substance GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0043499//eukaryotic cell surface binding;GO:0030971//receptor tyrosine kinase binding;GO:0004859//phospholipase inhibitor activity GO:0014704//intercalated disc;GO:0009897//external side of plasma membrane;GO:0042995//cell projection;GO:0042383//sarcolemma;GO:0005737//cytoplasm;GO:0072563//endothelial microparticle 325 tr|A0A024RCB5|A0A024RCB5_HUMAN Chitinase domain containing 1, isoform CRA_a OS=Homo sapiens GN=CHID1 PE=3 SV=1 51562 MRTLFNLLWLALACSPVHTTLSKSDAKKAASKTLLEKSQFSDKPVQDRGLVVTDLKAESVVLEHRSYCSAKARDRHFAGDVLGYVTPWNSHGYDVTKVFGSKFTQISPVWLQLKRRGREMFEVTGLHDVDQGWMRAVRKHAKGLHIVPRLLFEDWTYDDFRNVLDSEDEIEELSKTVVQVAKNQHFDGFVVEVWNQLLSQKRVGLIHMLTHLAEALHQARLLALLVIPPAITPGTDQLGMFTHKEFEQLAPVLDGFSLMTYDYSTAHQPGPNAPLSWVRACVQVLDPKSKWRSKILLGLNFYGMDYATSKDAREPVVGARYIQTLKDHRPRMVWDSQASEHFFEYKNRLLPNPESLQVRLELARELGVGVSIWELGQGLDYFYDLL 90 6.7 3 4 4 2 2 1.286 1.07 0.949 3 3 3 - - - 1.101666667 0.170717115 tr|A0A024RCB5|A0A024RCB5_HUMAN 100 0 gi|119622818|gb|EAX02413.1| chitinase domain containing 1, isoform CRA_a [Homo sapiens] >gi|119622819|gb|EAX02414.1| chitinase domain containing 1, isoform CRA_a [Homo sapiens] 96.44 0 sp|Q9BWS9|CHID1_HUMAN Chitinase domain-containing protein 1 OS=Homo sapiens GN=CHID1 PE=1 SV=1 100 1.00E-30 E9PKF1 E9PKF1_HUMAN Chitinase domain-containing protein 1 (Fragment) OS=Homo sapiens GN=CHID1 PE=4 SV=1 XF0848 55.1 2.00E-07 COG3858 Predicted glycosyl hydrolase R General function prediction only ; - GO:0005975//carbohydrate metabolic process;GO:0006032//chitin catabolic process;GO:0045087//innate immune response GO:0004568//chitinase activity;GO:0043169//cation binding GO:0005764//lysosome;GO:0005576//extracellular region 326 tr|M0QZN2|M0QZN2_HUMAN 40S ribosomal protein S5 OS=Homo sapiens GN=RPS5 PE=1 SV=1 17606 MTEWETAAPAVAETPDIKLFGKWSTDDVQINDISLQNPLQVLVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR 119 20.9 4 3 3 2 2 0.741 0.667 0.693 2 2 2 - - - 0.700333333 0.037541089 tr|M0QZN2|M0QZN2_HUMAN 100 6.00E-50 gi|224151960|ref|XP_002196941.1| PREDICTED: 40S ribosomal protein S5-like [Taeniopygia guttata] 94.95 7.00E-50 sp|P49041|RS5_CAEEL 40S ribosomal protein S5 OS=Caenorhabditis elegans GN=rps-5 PE=2 SV=1 100 1.00E-49 H0ZUJ9 H0ZUJ9_TAEGU Uncharacterized protein (Fragment) OS=Taeniopygia guttata GN=LOC100225758 PE=4 SV=1 SPAC328.10c 171 3.00E-43 COG0049 Ribosomal protein S7 J Translation, ribosomal structure and biogenesis ; K02989|1|4e-52|202|mdo:100017861|small subunit ribosomal protein S5e GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006450//regulation of translational fidelity;GO:0006415//translational termination;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome GO:0022627//cytosolic small ribosomal subunit 327 tr|A0A024RAB6|A0A024RAB6_HUMAN Heparan sulfate proteoglycan 2 (Perlecan), isoform CRA_b OS=Homo sapiens GN=HSPG2 PE=4 SV=1 495433 MRWTHSYLSDDEDMLADSISGDDLGSGDLGSGDFQMVYFRALVNFTRSIEYSPQLEDAGSREFREVSEAVVDTLESEYLKIPGDQVVSVVFIKELDGWVFVELDVGSEGNADGAQIQEMLLRVISSGSVASYVTSPQGFQFRRLGTVPQFPRACTEAEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETTSLPPRPETTIMRQPPVTHAPQPLLPGSVRPLPCGPQEAACRNGHCIPRDYLCDGQEDCEDGSDELDCGPPPPCEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMVFGIPDGVLELVPQRGPCPDGHFYLEHSAACLPCFCFGITSVCQSTRRFRDQIRLRFDQPDDFKGVNVTMPAQPGTPPLSSTQLQIDPSLHEFQLVDLSRRFLVHDSFWALPEQFLGNKVDSYGGSLRYNVRYELARGMLEPVQRPDVVLVGAGYRLLSRGHTPTQPGALNQRQVQFSEEHWVHESGRPVQRAELLQVLQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHATSHGRAHSVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASSCDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSRHCTSSSWSRAQLHGASEEPGHFSLTNAASTHTTNEGIFSPTPGELGFSSFHRLLSGPYFWSLPSRFLGDKVTSYGGELRFTVTQRSQPGSTPLHGQPLVVLQGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQRPDGQPATREHLLMALAGIDTLLIRASYAQQPAESRVSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYTRHLISTHFAPGDFQGFALVNPQRNSRLTGEFTVEPVPEGAQLSFGNFAQLGHESFYWQLPETYQGDKVAAYGGKLRYTLSYTAGPQGSPLSDPDVQITGNNIMLVASQPALQGPERRSYEIMFREEFWRRPDGQPATREHLLMALADLDELLIRATFSSVPLAASISAVSLEVAQPGPSNRPRALEVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPERVVPYFTQTPYSFLPLPTIKDAYRKFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMATIRHPTPLALGHFHTVTLLRSLTQGSLIVGDLAPVNGTSQGKFQGLDLNEELYLGGYPDYGAIPKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGISHCPTCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHRVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSQGIGQCYDSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTCQGTRCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGGNDAPGQYGAYFHDDGFLAFPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVLHSARPGAPPPQPLDLQHRAQAGANTRPCPS 1727 9.9 1 93 36 29 12 1.558 1.702 1.472 20 22 21 * * * 1.577333333 0.116212449 tr|A0A024RAB6|A0A024RAB6_HUMAN 100 0 gi|119615401|gb|EAW94995.1| heparan sulfate proteoglycan 2 (perlecan), isoform CRA_b [Homo sapiens] >gi|119615402|gb|EAW94996.1| heparan sulfate proteoglycan 2 (perlecan), isoform CRA_b [Homo sapiens] 99.95 0 sp|P98160|PGBM_HUMAN Basement membrane-specific heparan sulfate proteoglycan core protein OS=Homo sapiens GN=HSPG2 PE=1 SV=4 99.91 0 Q59EG0 Q59EG0_HUMAN Basement membrane-specific heparan sulfate proteoglycan core protein variant (Fragment) OS=Homo sapiens PE=2 SV=1 - - - - - - - K06255|1|0.0|8648|hsa:3339|heparan sulfate proteoglycan 2 (perlecan) GO:0006024//glycosaminoglycan biosynthetic process;GO:0006629//lipid metabolic process;GO:0001525//angiogenesis;GO:0005975//carbohydrate metabolic process;GO:0042157//lipoprotein metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0044281//small molecule metabolic process GO:0008022//protein C-terminus binding GO:0005796//Golgi lumen;GO:0005604//basement membrane;GO:0043202//lysosomal lumen;GO:0005615//extracellular space;GO:0005886//plasma membrane 328 sp|P08670|VIME_HUMAN Vimentin OS=Homo sapiens GN=VIM PE=1 SV=4 >tr|V9HWE1|V9HWE1_HUMAN Epididymis luminal protein 113 OS=Homo sapiens GN=HEL113 PE=2 SV=1 60673 MSTRSVSSSSYRRMFGGPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGVYATRSSAVRLRSSVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLNLRETNLDSLPLVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE 10346 57.1 - 484 395 29 24 0.714 0.631 0.633 303 308 300 - - - 0.659333333 0.047353282 sp|P08670|VIME_HUMAN 100 0 gi|167887751|gb|ACA06103.1| vimentin variant 3 [Homo sapiens] 100 0 sp|P08670|VIME_HUMAN Vimentin OS=Homo sapiens GN=VIM PE=1 SV=4 100 0 G2HJ38 G2HJ38_PANTR Vimentin OS=Pan troglodytes GN=VIM PE=2 SV=1 - - - - - - - K07606|1|0.0|798|hsa:7431|vimentin GO:0060020//Bergmann glial cell differentiation;GO:0070307//lens fiber cell development;GO:0014002//astrocyte development;GO:0045109//intermediate filament organization;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0030049//muscle filament sliding;GO:0019048//virus-host interaction;GO:0010977//negative regulation of neuron projection development;GO:0001701//in utero embryonic development GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding;GO:0005212//structural constituent of eye lens;GO:0019901//protein kinase binding;GO:0005200//structural constituent of cytoskeleton GO:0005829//cytosol;GO:0030424//axon;GO:0005777//peroxisome;GO:0031252//cell leading edge;GO:0005882//intermediate filament;GO:0005886//plasma membrane 329 sp|O15144|ARPC2_HUMAN Actin-related protein 2/3 complex subunit 2 OS=Homo sapiens GN=ARPC2 PE=1 SV=1 >tr|Q53R19|Q53R19_HUMAN Actin related protein 2/3 complex, subunit 2, 34kDa, isoform CRA_a OS=Homo sapiens GN=ARPC2 PE=2 SV=1 42335 MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR 137 15.3 - 13 13 5 5 0.906 0.596 0.664 7 6 7 - * * 0.722 0.16293557 sp|O15144|ARPC2_HUMAN 100 2.00E-158 gi|332246685|ref|XP_003272483.1| PREDICTED: actin-related protein 2/3 complex subunit 2 [Nomascus leucogenys] 100 1.00E-177 sp|O15144|ARPC2_HUMAN Actin-related protein 2/3 complex subunit 2 OS=Homo sapiens GN=ARPC2 PE=1 SV=1 100 3.00E-58 H7C3F9 H7C3F9_HUMAN Actin-related protein 2/3 complex subunit 2 (Fragment) OS=Homo sapiens GN=ARPC2 PE=4 SV=1 - - - - - - - K05758|1|1e-177|622|mcc:700536|actin related protein 2/3 complex, subunit 2 GO:0006928//cellular component movement;GO:0030838//positive regulation of actin filament polymerization GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton GO:0005885//Arp2/3 protein complex;GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0005925//focal adhesion;GO:0005794//Golgi apparatus 330 tr|Q4VAP9|Q4VAP9_HUMAN COL8A2 protein (Fragment) OS=Homo sapiens GN=COL8A2 PE=2 SV=1 70518 GRHAGDSDTPVFAAAAATEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT 166 16.3 4 8 8 6 6 1.467 2.731 1.93 5 6 6 - * * 2.042666667 0.639487555 tr|Q4VAP9|Q4VAP9_HUMAN 100 2.00E-09 gi|470600191|ref|XP_004312167.1| PREDICTED: collagen alpha-2(VIII) chain [Tursiops truncatus] 100 5.00E-87 sp|P25067|CO8A2_HUMAN Collagen alpha-2(VIII) chain OS=Homo sapiens GN=COL8A2 PE=1 SV=2 100 7.00E-09 H2PZI4 H2PZI4_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000171812 PE=4 SV=1 - - - - - - - K07296|1|2e-25|118|acs:100568236|adiponectin GO:0001525//angiogenesis;GO:0016337//cell-cell adhesion;GO:0048593//camera-type eye morphogenesis;GO:0030198//extracellular matrix organization;GO:0050673//epithelial cell proliferation GO:0030674//protein binding, bridging;GO:0005201//extracellular matrix structural constituent GO:0005788//endoplasmic reticulum lumen;GO:0005604//basement membrane;GO:0005581//collagen 331 tr|A0A087X208|A0A087X208_HUMAN Agrin OS=Homo sapiens GN=AGRN PE=4 SV=1 222865 MRITLRNLEEVEFCVEDKPGTHFTPVPPTPPDACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATCAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEAVAPSTHPTSASVTVTTPGLLLSQALPAPPGALPLAPSSTAHSQTTPPPSSRPRTTASVPRTTVWPVLTVPPTAPSPAPSLVASAFGESGSTDGSSDEELSGDQEASGGGSGGLEPLEGSSVATPGPPVERASCYNSALGCCSDGKTPSLDAEGSNCPATKVFQGVLELEGVEGQELFYTPEMADPKSELFGETARSIESTLDDLFRNSDVKKDFRSVRLRDLGPGKSVRAIVDVHFDPTTAFRAPDVARALLRQIQVSRRRSLGVRRPLQEHVRFMDFDWFPAFITGATSGAIAAGATARATTASRLPSSAVTPRAPHPSHTSQPVAKTTAAPTTRRPPTTAPSRVPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALGGGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGAAPCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGESPKSRKVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESELANEIPVPETLDSGALHSEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPLGATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTKPELRPCPTP 349 5 1 17 17 8 8 1.327 1.086 0.995 12 12 13 * - - 1.136 0.171554656 tr|A0A087X208|A0A087X208_HUMAN 100 0 gi|54261508|gb|AAH84578.1| AGRN protein, partial [Homo sapiens] 99.95 0 sp|O00468|AGRIN_HUMAN Agrin OS=Homo sapiens GN=AGRN PE=1 SV=4 100 3.00E-177 E9PD05 E9PD05_HUMAN Agrin OS=Homo sapiens GN=AGRN PE=4 SV=2 - - - - - - - K06254|1|0.0|3364|hsa:375790|agrin GO:0007411//axon guidance;GO:0006024//glycosaminoglycan biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0045162//clustering of voltage-gated sodium channels;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0043113//receptor clustering;GO:0050808//synapse organization;GO:0030204//chondroitin sulfate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0044281//small molecule metabolic process GO:0043236//laminin binding;GO:0005200//structural constituent of cytoskeleton GO:0005796//Golgi lumen;GO:0043202//lysosomal lumen;GO:0005605//basal lamina;GO:0005886//plasma membrane 332 tr|B4E3Q1|B4E3Q1_HUMAN cDNA FLJ61580, highly similar to Calsyntenin-1 OS=Homo sapiens PE=2 SV=1 124213 MLRRPAPALAPAARLLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAESFEVTVTKEGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPTCTPGWQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQATVELETSHIGKGCDRDTYSEKSLHRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSDQVFEFNGTQAVRIPDGVVSVSPKEPFTISVWMRHGPFGRKKETILCSSDKTDMNRHHYSLYVHGCRLIFLFRQDPSEEKKYRPAEFHWKLNQVCDEEWHHYVLNVEFPSVTLYVDGTSHEPFSVTEDYPLHPSKIETQLVVGACWQGGDLHMTQFFRGNLAGLTLRSGKLADKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDKAMQHISYLNSRQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGVHHFARAASEFESSEGVFLFPELRIISTITREVEPEGDGAEDPTVQESLVSEEIVHDLDTCEVTVEGEELNHEQESLEVDMARLQQKGIEVSSSELGMTFTGVDTMASYEEVLHLLRYRNWHARSLLDRKFKLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFVDLSGHNLANPHPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTMRDQDTGKENEMDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQQLEWDDSTLSY 511 12.5 1 36 36 10 10 1.06 0.842 1.035 19 19 18 - * - 0.979 0.119302137 tr|B4E3Q1|B4E3Q1_HUMAN 100 0 gi|194388358|dbj|BAG65563.1| unnamed protein product [Homo sapiens] 98.01 0 sp|O94985|CSTN1_HUMAN Calsyntenin-1 OS=Homo sapiens GN=CLSTN1 PE=1 SV=1 100 0 B4E3Q1 B4E3Q1_HUMAN CTF1-alpha OS=Homo sapiens GN=CLSTN1 PE=2 SV=1 - - - - - - - K04601|1|8e-13|76.6|bfo:BRAFLDRAFT_130073|cadherin EGF LAG seven-pass G-type receptor 2 (flamingo)!K04600|5|3e-10|68.6|dvi:Dvir_GJ22222|cadherin EGF LAG seven-pass G-type receptor 1 (flamingo) GO:0007156//homophilic cell adhesion GO:0005509//calcium ion binding GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0016021//integral to membrane;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0042995//cell projection 333 tr|D6RDU5|D6RDU5_HUMAN Septin-11 (Fragment) OS=Homo sapiens GN=SEPT11 PE=1 SV=1 54931 MNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKK 218 14.2 3 15 15 4 4 0.785 0.7 0.751 11 11 11 * - * 0.745333333 0.042782395 tr|D6RDU5|D6RDU5_HUMAN 100 0 gi|63991119|gb|AAY40922.1| unknown [Homo sapiens] 100 0 sp|Q8C1B7|SEP11_MOUSE Septin-11 OS=Mus musculus GN=Sept11 PE=1 SV=4 100 0 F7H547 F7H547_CALJA Uncharacterized protein OS=Callithrix jacchus GN=SEPT11 PE=3 SV=1 SPAC4F10.11 264 2.00E-70 COG5019 Septin family protein DZ Cell cycle control, cell division, chromosome partitioning ; Cytoskeleton ; K04557|1|8e-70|264|xla:779425|peanut-like protein 1 (cell division control related protein 1)!K13737|4|2e-68|259|acs:100556344|septin 1 GO:0051291//protein heterooligomerization;GO:0007049//cell cycle;GO:0051301//cell division GO:0005525//GTP binding;GO:0005515//protein binding GO:0043197//dendritic spine;GO:0030054//cell junction;GO:0030424//axon;GO:0001725//stress fiber;GO:0031105//septin complex;GO:0045202//synapse 334 sp|Q9HCU0|CD248_HUMAN Endosialin OS=Homo sapiens GN=CD248 PE=1 SV=1 85237 MLLRLLLAWAAAGPTLGQDPWAAEPRAACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAVYTTPFHLVSTEFEWLPFGSVAAVQCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAGAMGAQASQDLGDELLDDGEDEEDEDEAWKAFNGGWTEMPGILWMEPTQPPDFALAYRPSFPEDREPQIPYPEPTWPPPLSAPRVPYHSSVLSVTRPVVVSATHPTLPSAHQPPVIPATHPALSRDHQIPVIAANYPDLPSAYQPGILSVSHSAQPPAHQPPMISTKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPPNHAPLVTTLGAQLPPQAPDALVLRTQATQLPIIPTAQPSLTTTSRSPVSPAHQISVPAATQPAALPTLLPSQSPTNQTSPISPTHPHSKAPQIPREDGPSPKLALWLPSPAPTAAPTALGEAGLAEHSQRDDRWLLVALLVPTCVFLVVLLALGIVYCTRCGPHAPNKRITDCYRWVIHAGSKSPTEPMPPRGSLTGVQTCRTSV 362 5.8 - 12 12 4 4 1.034 1.129 0.706 9 10 10 - - * 0.956333333 0.221937679 sp|Q9HCU0|CD248_HUMAN 100 0 gi|9966885|ref|NP_065137.1| endosialin precursor [Homo sapiens] >gi|74752810|sp|Q9HCU0.1|CD248_HUMAN RecName: Full=Endosialin; AltName: Full=Tumor endothelial marker 1; AltName: CD_antigen=CD248; Flags: Precursor >gi|9857400|gb|AAG00867.1|AF279142_1 tumor endothelial marker 1 precursor [Homo sapiens] >gi|13277301|emb|CAC34381.1| endosialin protein [Homo sapiens] >gi|55930990|gb|AAH51340.1| CD248 molecule, endosialin [Homo sapiens] >gi|119594917|gb|EAW74511.1| CD248 antigen, endosialin [Homo sapiens] 100 0 sp|Q9HCU0|CD248_HUMAN Endosialin OS=Homo sapiens GN=CD248 PE=1 SV=1 99.19 0 H2RIA1 H2RIA1_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000174807 PE=4 SV=1 - - - - - - - K06706|1|0.0|1300|hsa:57124|CD248 antigen, endosialin - GO:0030246//carbohydrate binding;GO:0005509//calcium ion binding GO:0016021//integral to membrane;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0005886//plasma membrane 335 tr|A0A024R8Q0|A0A024R8Q0_HUMAN Septin 9, isoform CRA_b OS=Homo sapiens GN=SEPT9 PE=3 SV=1 57763 MEPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATEAAPSCVGDMADTPRDAGLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGSSAMANGVEEKEPEAPEM 119 11.6 2 11 11 4 4 0.879 0.805 0.689 6 6 6 - - - 0.791 0.095770559 tr|A0A024R8Q0|A0A024R8Q0_HUMAN 100 0 gi|194385318|dbj|BAG65036.1| unnamed protein product [Homo sapiens] 99.76 0 sp|Q9UHD8|SEPT9_HUMAN Septin-9 OS=Homo sapiens GN=SEPT9 PE=1 SV=2 100 5.00E-137 Q4R474 Q4R474_MACFA Testis cDNA clone: QtsA-11995, similar to human MLL septin-like fusion (MSF), OS=Macaca fascicularis PE=2 SV=1 SPAC821.06 319 6.00E-87 COG5019 Septin family protein DZ Cell cycle control, cell division, chromosome partitioning ; Cytoskeleton ; K04557|1|1e-84|313|dre:335925|peanut-like protein 1 (cell division control related protein 1) GO:0051291//protein heterooligomerization;GO:0007049//cell cycle;GO:0051301//cell division;GO:0006184//GTP catabolic process GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding GO:0005874//microtubule;GO:0001725//stress fiber;GO:0048471//perinuclear region of cytoplasm 336 sp|Q16658|FSCN1_HUMAN Fascin OS=Homo sapiens GN=FSCN1 PE=1 SV=3 63945 MTANGTAEAVQIQFGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAADKDGNVTCEREVPGPDCRFLIVAHDDGRWSLQSEAHRRYFGGTEDRLSCFAQTVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQRYSVQTADHRFLRHDGRLVARPEPATGYTLEFRSGKVAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTKKCAFRTHTGKYWTLTATGGVQSTASSKNASCYFDIEWRDRRITLRASNGKFVTSKKNGQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEFNDGAYNIKDSTGKYWTVGSDSAVTSSGDTPVDFFFEFCDYNKVAIKVGGRYLKGDHAGVLKASAETVDPASLWEY 317 27 - 14 14 9 9 0.887 0.807 0.866 10 10 10 - - - 0.853333333 0.041476901 sp|Q16658|FSCN1_HUMAN 100 0 gi|4507115|ref|NP_003079.1| fascin [Homo sapiens] >gi|2498357|sp|Q16658.3|FSCN1_HUMAN RecName: Full=Fascin; AltName: Full=55 kDa actin-bundling protein; AltName: Full=Singed-like protein; AltName: Full=p55 >gi|11513470|pdb|1DFC|A Chain A, Crystal Structure Of Human Fascin, An Actin-Crosslinking Protein >gi|11513471|pdb|1DFC|B Chain B, Crystal Structure Of Human Fascin, An Actin-Crosslinking Protein >gi|293651974|pdb|3LLP|A Chain A, 1.8 Angstrom Human Fascin 1 Crystal Structure >gi|293651975|pdb|3LLP|B Chain B, 1.8 Angstrom Human Fascin 1 Crystal Structure >gi|458028|gb|AAA86442.1| actin bundling protein [Homo sapiens] >gi|497269|gb|AAA62201.1| actin bundling protein [Homo sapiens] >gi|12653499|gb|AAH00521.1| Fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) [Homo sapiens] >gi|14044046|gb|AAH07948.1| FSCN1 protein [Homo sapiens] >gi|14124930|gb|AAH07988.1| Fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) [Homo sapiens] >gi|15625241|gb|AAL01526.1| fascin [Homo sapiens] >gi|30582111|gb|AAP35282.1| fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) [Homo sapiens] >gi|119607752|gb|EAW87346.1| fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus), isoform CRA_c [Homo sapiens] 100 0 sp|Q16658|FSCN1_HUMAN Fascin OS=Homo sapiens GN=FSCN1 PE=1 SV=3 100 2.00E-64 C9JPH9 C9JPH9_HUMAN Fascin (Fragment) OS=Homo sapiens GN=FSCN1 PE=4 SV=1 - - - - - - - K11978|1|7e-100|364|dpe:Dper_GL15138|E3 ubiquitin-protein ligase UBR3 [EC:6.3.2.19] GO:0016477//cell migration;GO:0008283//cell proliferation;GO:0051017//actin filament bundle assembly GO:0030674//protein binding, bridging;GO:0008144//drug binding;GO:0051015//actin filament binding GO:0005737//cytoplasm;GO:0030054//cell junction;GO:0071437//invadopodium;GO:0030175//filopodium;GO:0001725//stress fiber 337 tr|Q5STU3|Q5STU3_HUMAN Spliceosome RNA helicase DDX39B OS=Homo sapiens GN=DDX39B PE=1 SV=2 57996 MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRCYPLSPSRWPEQAGLAPRAWLSHLCPMRMMPRSSMMCRIALRSILVSCLMR 81 6.8 1 6 6 3 3 1.941 0.89 --- 2 2 1 - - - 1.4155 0.743169227 tr|Q5STU3|Q5STU3_HUMAN 100 3.00E-12 gi|119623810|gb|EAX03405.1| hCG2005638, isoform CRA_b [Homo sapiens] 100 0 sp|Q29024|DX39B_PIG Spliceosome RNA helicase DDX39B OS=Sus scrofa GN=DDX39B PE=3 SV=2 100 1.00E-168 B0UZ99 B0UZ99_HUMAN HLA-B associated transcript 1 (Fragment) OS=Homo sapiens GN=BAT1 PE=4 SV=1 SPAC17G6.14c 541 9.00E-154 COG0513 Superfamily II DNA and RNA helicases LKJ Replication, recombination and repair ; Transcription ; Translation, ribosomal structure and biogenesis ; K12812|1|0.0|776|mdo:100022951|ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13] GO:0010501//RNA secondary structure unwinding;GO:0000245//spliceosomal complex assembly;GO:0046784//intronless viral mRNA export from host nucleus GO:0043008//ATP-dependent protein binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0030621//U4 snRNA binding;GO:0017070//U6 snRNA binding GO:0005687//U4 snRNP;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0005688//U6 snRNP;GO:0000346//transcription export complex;GO:0005737//cytoplasm 338 sp|Q9GZP0|PDGFD_HUMAN Platelet-derived growth factor D OS=Homo sapiens GN=PDGFD PE=1 SV=1 50065 MHRLIFVYTLICANFCSCRDTSATPQSASIKALRNANLRRDESNHLTDLYRRDETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAASETNWESVTSSISGVSYNSPSVTDPTLIADALDKKIAEFDTVEDLLKYFNPESWQEDLENMYLDTPRYRGRSYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQRCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERCDCICSSRPPR 214 7.6 - 11 11 3 3 2.316 1.568 2.916 5 7 6 * * * 2.266666667 0.675352747 sp|Q9GZP0|PDGFD_HUMAN 100 0 gi|13376808|ref|NP_079484.1| platelet-derived growth factor D isoform 1 precursor [Homo sapiens] >gi|74717921|sp|Q9GZP0.1|PDGFD_HUMAN RecName: Full=Platelet-derived growth factor D; Short=PDGF-D; AltName: Full=Iris-expressed growth factor; AltName: Full=Spinal cord-derived growth factor B; Short=SCDGF-B; Contains: RecName: Full=Platelet-derived growth factor D, latent form; Short=PDGFD latent form; Contains: RecName: Full=Platelet-derived growth factor D, receptor-binding form; Short=PDGFD receptor-binding form; Flags: Precursor >gi|11640580|gb|AAG39287.1|AF113216_1 MSTP036 [Homo sapiens] >gi|14193796|gb|AAK56136.1|AF336376_1 platelet-derived growth factor D [Homo sapiens] >gi|11602808|dbj|BAB18903.1| spinal cord-derived growth factor-B [Homo sapiens] >gi|13432061|gb|AAK20081.1| iris-expressed growth factor long form [Homo sapiens] >gi|13774336|gb|AAK38840.1| platelet-derived growth factor D [Homo sapiens] >gi|119587449|gb|EAW67045.1| platelet derived growth factor D, isoform CRA_a [Homo sapiens] 100 0 sp|Q9GZP0|PDGFD_HUMAN Platelet-derived growth factor D OS=Homo sapiens GN=PDGFD PE=1 SV=1 100 0 H2Q4N6 H2Q4N6_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000170962 PE=3 SV=1 - - - - - - - K05450|1|0.0|773|hsa:80310|platelet derived growth factor C/D GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0051781//positive regulation of cell division;GO:0071230//cellular response to amino acid stimulus;GO:0007275//multicellular organismal development GO:0008083//growth factor activity GO:0000139//Golgi membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region 339 tr|Q6IBG1|Q6IBG1_HUMAN MYL9 protein OS=Homo sapiens GN=MYL9 PE=2 SV=1 24457 MSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKHD 192 27.9 1 6 4 3 2 0.689 0.642 0.591 2 2 2 - - - 0.640666667 0.049013604 tr|Q6IBG1|Q6IBG1_HUMAN 100 3.00E-86 gi|48145803|emb|CAG33124.1| MYL9 [Homo sapiens] 99.42 5.00E-86 sp|Q5RBA4|MYL9_PONAB Myosin regulatory light polypeptide 9 OS=Pongo abelii GN=MYL9 PE=2 SV=3 100 2.00E-84 H1A1N6 H1A1N6_TAEGU Uncharacterized protein (Fragment) OS=Taeniopygia guttata GN=MYL9 PE=4 SV=1 SPAC3A12.14 114 9.00E-26 COG5126 Ca2+-binding protein (EF-Hand superfamily) TZDR Signal transduction mechanisms ; Cytoskeleton ; Cell cycle control, cell division, chromosome partitioning ; General function prediction only ; K12755|1|5e-88|323|cfa:485856|myosin regulatory light chain 9 GO:0007411//axon guidance;GO:0008360//regulation of cell shape;GO:0072661//protein targeting to plasma membrane;GO:0006937//regulation of muscle contraction GO:0008307//structural constituent of muscle;GO:0005509//calcium ion binding;GO:0035254//glutamate receptor binding GO:0005829//cytosol;GO:0030018//Z disc;GO:0005859//muscle myosin complex;GO:0001725//stress fiber 340 tr|X6RJP6|X6RJP6_HUMAN Transgelin-2 (Fragment) OS=Homo sapiens GN=TAGLN2 PE=1 SV=1 25198 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQA 422 39.6 1 22 22 5 5 0.815 0.703 0.706 11 11 11 - * * 0.741333333 0.063814836 tr|X6RJP6|X6RJP6_HUMAN 100 4.00E-107 gi|355558625|gb|EHH15405.1| hypothetical protein EGK_01490 [Macaca mulatta] 100 2.00E-107 sp|P37802|TAGL2_HUMAN Transgelin-2 OS=Homo sapiens GN=TAGLN2 PE=1 SV=3 100 4.00E-106 F6RKI4 F6RKI4_MACMU Transgelin-2 OS=Macaca mulatta GN=Mmu.3153 PE=2 SV=1 YOR367w 89.7 3.00E-18 COG5199 Calponin Z Cytoskeleton ; - GO:0007517//muscle organ development GO:0005515//protein binding GO:0031965//nuclear membrane;GO:0005886//plasma membrane 341 sp|P05543|THBG_HUMAN Thyroxine-binding globulin OS=Homo sapiens GN=SERPINA7 PE=1 SV=2 55459 MSPFLYLVLLVLGLHATIHCASPEGKVTACHSSQPNATLYKMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTEA 203 9.6 - 11 11 4 4 0.831 0.572 0.738 7 7 7 - * - 0.713666667 0.131203404 sp|P05543|THBG_HUMAN 100 0 gi|205277441|ref|NP_000345.2| thyroxine-binding globulin precursor [Homo sapiens] >gi|1351236|sp|P05543.2|THBG_HUMAN RecName: Full=Thyroxine-binding globulin; AltName: Full=Serpin A7; AltName: Full=T4-binding globulin; Flags: Precursor >gi|37142|emb|CAA45509.1| thyroxine-binding globulin [Homo sapiens] >gi|405514|gb|AAA16067.1| thyroxine-binding globulin [Homo sapiens] >gi|18089129|gb|AAH20747.1| Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 [Homo sapiens] >gi|119623152|gb|EAX02747.1| serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7, isoform CRA_c [Homo sapiens] >gi|119623153|gb|EAX02748.1| serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7, isoform CRA_c [Homo sapiens] 100 0 sp|P05543|THBG_HUMAN Thyroxine-binding globulin OS=Homo sapiens GN=SERPINA7 PE=1 SV=2 99.28 0 G3RVV8 G3RVV8_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=SERPINA7 PE=3 SV=1 all0778 166 1.00E-40 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K04525|1|2e-93|343|oaa:100086374|serpin peptidase inhibitor, clade A, member 3!K03984|2|5e-92|338|acs:100560217|alpha-1-antitrypsin GO:0034695//response to prostaglandin E stimulus;GO:0010951//negative regulation of endopeptidase activity;GO:0042493//response to drug;GO:0043434//response to peptide hormone stimulus;GO:0033189//response to vitamin A;GO:0007568//aging;GO:0009791//post-embryonic development;GO:0030162//regulation of proteolysis;GO:0051412//response to corticosterone stimulus GO:0004867//serine-type endopeptidase inhibitor activity;GO:0042562//hormone binding GO:0005615//extracellular space 342 sp|Q9HCB6|SPON1_HUMAN Spondin-1 OS=Homo sapiens GN=SPON1 PE=1 SV=2 109355 MRLSPAPLKLSRTPALLALALPLAAALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALRENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMIKMNPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC 99 8.6 - 9 9 6 6 0.89 2.079 2.75 3 3 3 - - - 1.906333333 0.941944974 sp|Q9HCB6|SPON1_HUMAN 100 3.00E-92 gi|197305053|pdb|3COO|A Chain A, The Crystal Structure Of Reelin-N Domain Of F-Spondin >gi|197305054|pdb|3COO|B Chain B, The Crystal Structure Of Reelin-N Domain Of F-Spondin 100 0 sp|Q9HCB6|SPON1_HUMAN Spondin-1 OS=Homo sapiens GN=SPON1 PE=1 SV=2 99.71 0 B3KMD1 B3KMD1_HUMAN cDNA FLJ10722 fis, clone NT2RP3001140, highly similar to Spondin-1 OS=Homo sapiens PE=2 SV=1 - - - - - - - K04598|1|5e-21|103|dre:566117|brain-specific angiogenesis inhibitor 3!K04596|4|8e-21|103|mmu:107831|brain-specific angiogenesis inhibitor 1 GO:0007155//cell adhesion GO:0005515//protein binding GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 343 tr|A8K878|A8K878_HUMAN cDNA FLJ77177, highly similar to Homo sapiens arginine-rich, mutated in early stage tumors (ARMET), mRNA OS=Homo sapiens PE=2 SV=1 28583 MRRMRRMWATQGLAVALALSVLPGSRALRPGDCEVCISYLGRFYQDLKDRDVTFSPATIENELIKFCREARGKENRLCYYIGATDDAATKIINEVSKPLAHHIPVEKICEKLKKKDSQICELKYDKQIDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPKAASARTDL 124 27.6 1 7 7 5 5 0.795 0.733 0.809 3 3 3 - - - 0.779 0.040447497 tr|A8K878|A8K878_HUMAN 100 2.00E-103 gi|119585542|gb|EAW65138.1| arginine-rich, mutated in early stage tumors [Homo sapiens] 100 6.00E-103 sp|P55145|MANF_HUMAN Mesencephalic astrocyte-derived neurotrophic factor OS=Homo sapiens GN=MANF PE=1 SV=3 100 7.00E-33 H7C2D6 H7C2D6_HUMAN Mesencephalic astrocyte-derived neurotrophic factor (Fragment) OS=Homo sapiens GN=MANF PE=4 SV=1 - - - - - - - K13190|1|6e-69|259|gga:770664|RNA-binding protein 15 GO:0002014//vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure;GO:0006986//response to unfolded protein GO:0008083//growth factor activity GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm 344 tr|B4DYY5|B4DYY5_HUMAN cDNA FLJ55671, highly similar to Ubiquitin-associated protein 2-like OS=Homo sapiens PE=2 SV=1 124613 MMTSVGTNRARGNWEQPQNQNQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDGGQTESNEEGKENRDRDRDYSRRRGGPPRRGRGASRGRECMHGALSKPAVVRGQENGLDGTKSGGPSGRGTERGRRGRGRGRGGSGRRGGRFSAQGMGTFNPADYAEPANTDDNYGNSSGNTWNNTGHFEPDDGTSAWRTATEEWGTEDWNEDLSETKIFTASNVSSVPLPAENVTITAGQRIDLAVLLGKTPSTMENDSSNLDPSQAPSLAQPLVFSNSKQTAISQPASGNTFSHHSMVSMLGKGFGDVGEAKGGSTTGSQFLEQFKTAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLKNPSDSAVHSPFTKRQAFTPSSTMMEVFLQEKSPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQKLKQQKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLSDYESTPTTSASSSQAPSSLYTSTASESSSTISSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPFTSSIPPLNETVSAASLLTTTNQHSSSLGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQQNQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTSSNTGVPDISGSVYSKTQSFEKQGFHSGTPAASFNLPSALGSGGPINPATAAAYPPAPFMHILTPHQQPHSQILHHHLQQDGQDILNFVDDQLGE 58 0.8 4 3 3 1 1 0.646 0.467 0.8 2 2 2 - - - 0.637666667 0.166656333 tr|B4DYY5|B4DYY5_HUMAN 100 6.00E-70 gi|426216707|ref|XP_004002599.1| PREDICTED: ubiquitin-associated protein 2-like isoform 5 [Ovis aries] 99.61 8.00E-113 sp|Q80X50|UBP2L_MOUSE Ubiquitin-associated protein 2-like OS=Mus musculus GN=Ubap2l PE=1 SV=1 100 2.00E-147 Q5VU77 Q5VU77_HUMAN Ubiquitin associated protein 2-like (Fragment) OS=Homo sapiens GN=UBAP2L PE=1 SV=1 - - - - - - - - GO:0007339//binding of sperm to zona pellucida GO:0005515//protein binding GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex 345 tr|A0A024R201|A0A024R201_HUMAN Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 13, isoform CRA_a OS=Homo sapiens GN=PSMD13 PE=4 SV=1 50477 MKDVPGFLQQSQSSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDVKSMEMLVEHQAHDILT 95 5.9 6 2 2 2 2 0.434 0.515 0.651 2 2 2 - - * 0.533333333 0.109655521 tr|A0A024R201|A0A024R201_HUMAN 100 0 gi|5453127|gb|AAD43442.1|AF107837_1 26S proteasome subunit p40.5 [Homo sapiens] >gi|12654533|gb|AAH01100.1| Proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 [Homo sapiens] >gi|12804645|gb|AAH01747.1| Proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 [Homo sapiens] >gi|30583453|gb|AAP35971.1| proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 [Homo sapiens] >gi|119581638|gb|EAW61234.1| proteasome (prosome, macropain) 26S subunit, non-ATPase, 13, isoform CRA_a [Homo sapiens] >gi|119581640|gb|EAW61236.1| proteasome (prosome, macropain) 26S subunit, non-ATPase, 13, isoform CRA_a [Homo sapiens] 99.73 0 sp|Q9UNM6|PSD13_HUMAN 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens GN=PSMD13 PE=1 SV=2 100 1.00E-179 B4DJ66 B4DJ66_HUMAN 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens GN=PSMD13 PE=2 SV=1 - - - - - - - K03039|1|0.0|717|pon:100454341|26S proteasome regulatory subunit N9 GO:0000209//protein polyubiquitination;GO:0007127//meiosis I;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0016032//viral reproduction;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest - GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle 346 tr|A6XND0|A6XND0_HUMAN Insulin-like growth factor binding protein 3 OS=Homo sapiens GN=IGFBP3 PE=2 SV=1 36838 MQRARPTLWAAALTLLVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK 931 31.9 2 47 47 6 6 1.521 1.158 1.356 30 31 31 * * * 1.345 0.181749828 tr|A6XND0|A6XND0_HUMAN 100 3.00E-140 gi|114319031|gb|ABI63364.1| insulin-like growth factor binding protein 3 [Homo sapiens] 96.63 7.00E-133 sp|P17936|IBP3_HUMAN Insulin-like growth factor-binding protein 3 OS=Homo sapiens GN=IGFBP3 PE=1 SV=2 100 2.00E-77 H0Y5K2 H0Y5K2_HUMAN Insulin-like growth factor-binding protein 3 (Fragment) OS=Homo sapiens GN=IGFBP3 PE=4 SV=1 - - - - - - - K10138|1|9e-137|486|mcc:696868|insulin-like growth factor-binding protein 3 GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0001558//regulation of cell growth;GO:0009968//negative regulation of signal transduction;GO:0044342//type B pancreatic cell proliferation;GO:0001933//negative regulation of protein phosphorylation;GO:0014912//negative regulation of smooth muscle cell migration;GO:0043065//positive regulation of apoptotic process;GO:0045663//positive regulation of myoblast differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0010906//regulation of glucose metabolic process GO:0031995//insulin-like growth factor II binding;GO:0046872//metal ion binding;GO:0031994//insulin-like growth factor I binding;GO:0001968//fibronectin binding;GO:0008160//protein tyrosine phosphatase activator activity GO:0042567//insulin-like growth factor ternary complex;GO:0042568//insulin-like growth factor binary complex;GO:0005634//nucleus 347 sp|O95881|TXD12_HUMAN Thioredoxin domain-containing protein 12 OS=Homo sapiens GN=TXNDC12 PE=1 SV=1 23624 METRPRLGATCLLGFSFLLLVISSDGHNGLGKGFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAESTEISELSHNFVMVNLEDEEEPKDEDFSPDGGYIPRILFLDPSGKVHPEIINENGNPSYKYFYVSAEQVVQGMKEAQERLTGDAFRKKHLEDEL 171 22.1 - 10 10 3 3 0.9 0.681 0.742 6 5 5 - - * 0.774333333 0.113023596 sp|O95881|TXD12_HUMAN 100 2.00E-97 gi|7705696|ref|NP_056997.1| thioredoxin domain-containing protein 12 precursor [Homo sapiens] >gi|29839456|sp|O95881.1|TXD12_HUMAN RecName: Full=Thioredoxin domain-containing protein 12; AltName: Full=Endoplasmic reticulum resident protein 18; Short=ER protein 18; Short=ERp18; AltName: Full=Endoplasmic reticulum resident protein 19; Short=ER protein 19; Short=ERp19; AltName: Full=Thioredoxin-like protein p19; AltName: Full=hTLP19; Flags: Precursor >gi|13111707|gb|AAH01493.1| Thioredoxin domain containing 12 (endoplasmic reticulum) [Homo sapiens] >gi|14286304|gb|AAH08953.1| Thioredoxin domain containing 12 (endoplasmic reticulum) [Homo sapiens] >gi|23477616|gb|AAN34781.1| thioredoxin-like protein p19 [Homo sapiens] >gi|37183082|gb|AAQ89341.1| ETRP713 [Homo sapiens] >gi|119627205|gb|EAX06800.1| thioredoxin domain containing 12 (endoplasmic reticulum) [Homo sapiens] 100 3.00E-98 sp|O95881|TXD12_HUMAN Thioredoxin domain-containing protein 12 OS=Homo sapiens GN=TXNDC12 PE=1 SV=1 100 6.00E-97 H2PZ09 H2PZ09_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000117862 PE=4 SV=1 - - - - - - - K05360|1|3e-98|357|hsa:51060|protein-disulfide reductase (glutathione) [EC:1.8.4.2] GO:0045454//cell redox homeostasis GO:0019153//protein-disulfide reductase (glutathione) activity GO:0005788//endoplasmic reticulum lumen 348 tr|C0JYY2|C0JYY2_HUMAN Apolipoprotein B (Including Ag(X) antigen) OS=Homo sapiens GN=APOB PE=4 SV=1 625263 MDPPRPALLALLALPALLLLLLAGARAEEEMLENVSLVCPKDATRFKHLRKYTYNYEAESSSGVPGTADSRSATRINCKVELEVPQLCSFILKTSQCTLKEVYGFNPEGKALLKKTKNSEEFAAAMSRYELKLAIPEGKQVFLYPEKDEPTYILNIKRGIISALLVPPETEEAKQVLFLDTVYGNCSTHFTVKTRKGNVATEISTERDLGQCDRFKPIRTGISPLALIKGMTRPLSTLISSSQSCQYTLDAKRKHVAEAICKEQHLFLPFSYKNKYGMVAQVTQTLKLEDTPKINSRFFGEGTKKMGLAFESTKSTSPPKQAEAVLKTLQELKKLTISEQNIQRANLFNKLVTELRGLSDEAVTSLLPQLIEVSSPITLQALVQCGQPQCSTHILQWLKRVHANPLLIDVVTYLVALIPEPSAQQLREIFNMARDQRSRATLYALSHAVNNYHKTNPTGTQELLDIANYLMEQIQDDCTGDEDYTYLILRVIGNMGQTMEQLTPELKSSILKCVQSTKPSLMIQKAAIQALRKMEPKDKDQEVLLQTFLDDASPGDKRLAAYLMLMRSPSQADINKIVQILPWEQNEQVKNFVASHIANILNSEELDIQDLKKLVKEALKESQLPTVMDFRKFSRNYQLYKSVSLPSLDPASAKIEGNLIFDPNNYLPKESMLKTTLTAFGFASADLIEIGLEGKGFEPTLEALFGKQGFFPDSVNKALYWVNGQVPDGVSKVLVDHFGYTKDDKHEQDMVNGIMLSVEKLIKDLKSKEVPEARAYLRILGEELGFASLHDLQLLGKLLLMGARTLQGIPQMIGEVIRKGSKNDFFLHYIFMENAFELPTGAGLQLQISSSGVIAPGAKAGVKLEVANMQAELVAKPSVSVEFVTNMGIIIPDFARSGVQMNTNFFHESGLEAHVALKAGKLKFIIPSPKRPVKLLSGGNTLHLVSTTKTEVIPPLIENRQSWSVCKQVFPGLNYCTSGAYSNASSTDSASYYPLTGDTRLELELRPTGEIEQYSVSATYELQREDRALVDTLKFVTQAEGAKQTEATMTFKYNRQSMTLSSEVQIPDFDVDLGTILRVNDESTEGKTSYRLTLDIQNKKITEVALMGHLSCDTKEERKIKGVISIPRLQAEARSEILAHWSPAKLLLQMDSSATAYGSTVSKRVAWHYDEEKIEFEWNTGTNVDTKKMTSNFPVDLSDYPKSLHMYANRLLDHRVPQTDMTFRHVGSKLIVAMSSWLQKASGSLPYTQTLQDHLNSLKEFNLQNMGLPDFHIPENLFLKSDGRVKYTLNKNSLKIEIPLPFGGKSSRDLKMLETVRTPALHFKSVGFHLPSREFQVPTFTIPKLYQLQVPLLGVLDLSTNVYSNLYNWSASYSGGNTSTDHFSLRARYHMKADSVVDLLSYNVQGSGETTYDHKNTFTLSCDGSLRHKFLDSNIKFSHVEKLGNNPVSKGLLIFDASSSWGPQMSASVHLDSKKKQHLFVKEVKIDGQFRVSSFYAKGTYGLSCQRDPNTGRLNGESNLRFNSSYLQGTNQITGRYEDGTLSLTSTSDLQSGIIKNTASLKYENYELTLKSDTNGKYKNFATSNKMDMTFSKQNALLRSEYQADYESLRFFSLLSGSLNSHGLELNADILGTDKINSGAHKATLRIGQDGISTSATTNLKCSLLVLENELNAELGLSGASMKLTTNGRFREHNAKFSLDGKAALTELSLGSAYQAMILGVDSKNIFNFKVSQEGLKLSNDMMGSYAEMKFDHTNSLNIAGLSLDFSSKLDNIYSSDKFYKQTVNLQLQPYSLVTTLNSDLKYNALDLTNNGKLRLEPLKLHVAGNLKGAYQNNEIKHIYAISSAALSASYKADTVAKVQGVEFSHRLNTDIAGLASAIDMSTNYNSDSLHFSNVFRSVMAPFTMTIDAHTNGNGKLALWGEHTGQLYSKFLLKAEPLAFTFSHDYKGSTSHHLVSRKSISAALEHKVSALLTPAEQTGTWKLKTQFNNNEYSQDLDAYNTKDKIGVELTGRTLADLTLLDSPIKVPLLLSEPINIIDALEMRDAVEKPQEFTIVAFVKYDKNQDVHSINLPFFETLQEYFERNRQTIIVVLENVQRNLKHINIDQFVRKYRAALGKLPQQANDYLNSFNWERQVSHAKEKLTALTKKYRITENDIQIALDDAKINFNEKLSQLQTYMIQFDQYIKDSYDLHDLKIAIANIIDEIIEKLKSLDEHYHIRVNLVKTIHDLHLFIENIDFNKSGSSTASWIQNVDTKYQIRIQIQEKLQQLKRHIQNIDIQHLAGKLKQHIEAIDVRVLLDQLGTTISFERINDVLEHVKHFVINLIGDFEVAEKINAFRAKVHELIERYEVDQQIQVLMDKLVELAHQYKLKETIQKLSNVLQQVKIKDYFEKLVGFIDDAVKKLNELSFKTFIEDVNKFLDMLIKKLKSFDYHQFVDETNDKIREVTQRLNGEIQALELPQKAEALKLFLEETKATVAVYLESLQDTKITLIINWLQEALSSASLAHMKAKFRETLEDTRDRMYQMDIQQELQRYLSLVGQVYSTLVTYISDWWTLAAKNLTDFAEQYSIQDWAKRMKALVEQGFTVPEIKTILGTMPAFEVSLQALQKATFQTPDFIVPLTDLRIPSVQINFKDLKNIKIPSRFSTPEFTILNTFHIPSFTIDFVEMKVKIIRTIDQMLNSELQWPVPDIYLRDLKVEDIPLARITLPDFRLPEIAIPEFIIPTLNLNDFQVPDLHIPEFQLPHISHTIEVPTFGKLYSILKIQSPLFTLDANADIGNGTTSANEAGIAASITAKGESKLEVLNFDFQANAQLSNPKINPLALKESVKFSSKYLRTEHGSEMLFFGNAIEGKSNTVASLHTEKNTLELSNGVIVKINNQLTLDSNTKYFHKLNIPKLDFSSQADLRNEIKTLLKAGHIAWTSSGKGSWKWACPRFSDEGTHESQISFTIEGPLTSFGLSNKINSKHLRVNQNLVYESGSLNFSKLEIQSQVDSQHVGHSVLTAKGMALFGEGKAEFTGRHDAHLNGKVIGTLKNSLFFSAQPFEITASTNNEGNLKVRFPLRLTGKIDFLNNYALFLSPSAQQASWQVSARFNQYKYNQNFSAGNNENIMEAHVGINGEANLDFLNIPLTIPEMRLPYTIITTPPLKDFSLWEKTGLKEFLKTTKQSFDLSVKAQYKKNKHRHSITNPLAVLCEFISQSIKSFDRHFEKNRNNALDFVTKSYNETKIKFDKYKAEKSHDELPRTFQIPGYTVPVVNVEVSPFTIEMSAFGYVFPKAVSMPSFSILGSDVRVPSYTLILPSLELPVLHVPRNLKLSLPDFKELCTISHIFIPAMGNITYDFSFKSSVITLNTNAELFNQSDIVAHLLSSSSSVIDALQYKLEGTTRLTRKRGLKLATALSLSNKFVEGSHNSTVSLTTKNMEVSVATTTKAQIPILRMNFKQELNGNTKSKPTVSSSMEFKYDFNSSMLYSTAKGAVDHKLSLESLTSYFSIESSTKGDVKGSVLSREYSGTIASEANTYLNSKSTRSSVKLQGTSKIDDIWNLEVKENFAGEATLQRIYSLWEHSTKNHLQLEGLFFTNGEHTSKATLELSPWQMSALVQVHASQPSSFHDFPDLGQEVALNANTKNQKIRWKNEVRIHSGSFQSQVELSNDQEKAHLDIAGSLEGHLRFLKNIILPVYDKSLWDFLKLDVTTSIGRRQHLRVSTAFVYTKNPNGYSFSIPVKVLADKFIIPGLKLNDLNSVLVMPTFHVPFTDLQVPSCKLDFREIQIYKKLRTSSFALNLPTLPEVKFPEVDVLTKYSQPEDSLIPFFEITVPESQLTVSQFTLPKSVSDGIAALDLNAVANKIADFELPTIIVPEQTIEIPSIKFSVPAGIVIPSFQALTARFEVDSPVYNATWSASLKNKADYVETVLDSTCSSTVQFLEYELNVLGTHKIEDGTLASKTKGTFAHRDFSAEYEEDGKYEGLQEWEGKAHLNIKSPAFTDLHLRYQKDKKGISTSAASPAVGTVGMDMDEDDDFSKWNFYYSPQSSPDKKLTIFKTELRVRESDEETQIKVNWEEEAASGLLTSLKDNVPKATGVLYDYVNKYHWEHTGLTLREVSSKLRRNLQNNAEWVYQGAIRQIDDIDVRFQKAASGTTGTYQEWKDKAQNLYQELLTQEGQASFQGLKDNVFDGLVRVTQEFHMKVKHLIDSLIDFLNFPRFQFPGKPGIYTREELCTMFIREVGTVLSQVYSKVHNGSEILFSYFQDLVITLPFELRKHKLIDVISMYRELLKDLSKEAQEVFKAIQSLKTTEVLRNLQDLLQFIFQLIEDNIKQLKEMKFTYLINYIQDEINTIFNDYIPYVFKLLKENLCLNLHKFNEFIQNELQEASQELQQIHQYIMALREEYFDPSIVGWTVKYYELEEKIVSLIKNLLVALKDFHSEYIVSASNFTSQLSSQVEQFLHRNIQEYLSILTDPDGKGKEKIAELSATAQEIIKSQAIATKKIISDYHQQFRYKLQDFSDQLSDYYEKFIAESKRLIDLSIQNYHTFLIYITELLKKLQSTTVMNPYMKLAPGELTIIL 2670 17 - 150 150 65 65 1.633 3.908 0.832 92 72 52 * * - 2.124333333 1.595775778 tr|C0JYY2|C0JYY2_HUMAN 100 0 gi|178730|gb|AAB00481.1| apolipoprotein B-100 precursor [Homo sapiens] >gi|32187679|gb|AAP72970.1| apolipoprotein B (including Ag(x) antigen) [Homo sapiens] >gi|119621206|gb|EAX00801.1| apolipoprotein B (including Ag(x) antigen), isoform CRA_a [Homo sapiens] >gi|119621208|gb|EAX00803.1| apolipoprotein B (including Ag(x) antigen), isoform CRA_a [Homo sapiens] >gi|225131003|gb|ACN81311.1| apolipoprotein B (including Ag(x) antigen) [Homo sapiens] 99.93 0 sp|P04114|APOB_HUMAN Apolipoprotein B-100 OS=Homo sapiens GN=APOB PE=1 SV=2 100 0 A8MUN2 A8MUN2_HUMAN Apolipoprotein B-48 OS=Homo sapiens GN=APOB PE=4 SV=2 - - - - - - - K14462|1|0.0|9117|hsa:338|apolipoprotein B GO:0010886//positive regulation of cholesterol storage;GO:0042953//lipoprotein transport;GO:0009615//response to virus;GO:0032496//response to lipopolysaccharide;GO:0045540//regulation of cholesterol biosynthetic process;GO:0010269//response to selenium ion;GO:0042159//lipoprotein catabolic process;GO:0034374//low-density lipoprotein particle remodeling;GO:0048844//artery morphogenesis;GO:0006898//receptor-mediated endocytosis;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0071356//cellular response to tumor necrosis factor;GO:0009566//fertilization;GO:0034383//low-density lipoprotein particle clearance;GO:0007283//spermatogenesis;GO:0009791//post-embryonic development;GO:0050900//leukocyte migration;GO:0034379//very-low-density lipoprotein particle assembly;GO:0019433//triglyceride catabolic process;GO:0030317//sperm motility;GO:0007596//blood coagulation;GO:0042158//lipoprotein biosynthetic process;GO:0030301//cholesterol transport;GO:0007399//nervous system development;GO:0009743//response to carbohydrate stimulus;GO:0071379//cellular response to prostaglandin stimulus;GO:0001701//in utero embryonic development;GO:0006642//triglyceride mobilization;GO:0042632//cholesterol homeostasis GO:0050750//low-density lipoprotein particle receptor binding;GO:0005543//phospholipid binding;GO:0046982//protein heterodimerization activity;GO:0008201//heparin binding;GO:0019899//enzyme binding;GO:0017127//cholesterol transporter activity GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0034360//chylomicron remnant;GO:0005788//endoplasmic reticulum lumen;GO:0034361//very-low-density lipoprotein particle;GO:0005789//endoplasmic reticulum membrane;GO:0031904//endosome lumen;GO:0034363//intermediate-density lipoprotein particle;GO:0034359//mature chylomicron;GO:0005886//plasma membrane;GO:0034362//low-density lipoprotein particle;GO:0010008//endosome membrane;GO:0031983//vesicle lumen 349 tr|M0QXF7|M0QXF7_HUMAN UPF0556 protein C19orf10 (Fragment) OS=Homo sapiens GN=C19orf10 PE=1 SV=1 11851 XHQHFTCTIWRPQGKSYLYFTQFKAEVRGAEIEYAMAYSKAAFERESDVPLKTEEFEVTKTAVISAPQEKGDDQPHWTDGETEA 126 42.9 2 11 11 3 3 0.734 0.683 0.67 6 6 6 - * * 0.695666667 0.033827996 tr|M0QXF7|M0QXF7_HUMAN 100 5.00E-29 gi|3513302|gb|AAC33800.1| R33729_1, partial CDS [Homo sapiens] 95.45 9.00E-31 sp|Q969H8|CS010_HUMAN UPF0556 protein C19orf10 OS=Homo sapiens GN=C19orf10 PE=1 SV=1 97.3 3.00E-14 H2NX37 H2NX37_PONAB Uncharacterized protein (Fragment) OS=Pongo abelii GN=C19orf10 PE=4 SV=1 - - - - - - - - GO:0006987//activation of signaling protein activity involved in unfolded protein response - GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region 350 sp|P08572|CO4A2_HUMAN Collagen alpha-2(IV) chain OS=Homo sapiens GN=COL4A2 PE=1 SV=4 >tr|A0A024RDW8|A0A024RDW8_HUMAN Collagen, type IV, alpha 2, isoform CRA_a OS=Homo sapiens GN=COL4A2 PE=4 SV=1 193591 MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPEQSFQGSPSADTLKAGLIRTHISRCQVCMKNL 867 14.3 - 42 42 16 16 0.672 0.605 0.498 31 30 28 * * * 0.591666667 0.087762938 sp|P08572|CO4A2_HUMAN 100 8.00E-133 gi|8101724|gb|AAF72631.1|AF258350_1 canstatin, partial [Homo sapiens] >gi|15217055|gb|AAK92479.1|AF400430_1 canstatin [Homo sapiens] >gi|38349537|gb|AAR18250.1| canstatin [Homo sapiens] >gi|38426265|gb|AAR20245.1| endogenous angiogenesis inhibitor [Homo sapiens] 100 0 sp|P08572|CO4A2_HUMAN Collagen alpha-2(IV) chain OS=Homo sapiens GN=COL4A2 PE=1 SV=4 100 0 E7EPD1 E7EPD1_HUMAN Canstatin OS=Homo sapiens GN=COL4A2 PE=4 SV=2 - - - - - - - K06237|1|0.0|1281|hsa:1284|collagen, type IV, alpha GO:0007411//axon guidance;GO:0016525//negative regulation of angiogenesis;GO:0006351//transcription, DNA-dependent;GO:0030198//extracellular matrix organization GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent GO:0005788//endoplasmic reticulum lumen;GO:0005587//collagen type IV 351 sp|P11464|PSG1_HUMAN Pregnancy-specific beta-1-glycoprotein 1 OS=Homo sapiens GN=PSG1 PE=2 SV=1 53676 MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP 90 9.8 - 7 2 4 1 0.383 0.274 0.317 2 2 2 - - - 0.324666667 0.054902945 sp|P11464|PSG1_HUMAN 100 0 gi|296317345|ref|NP_001171754.1| pregnancy-specific beta-1-glycoprotein 1 isoform 2 precursor [Homo sapiens] >gi|129661|sp|P11464.1|PSG1_HUMAN RecName: Full=Pregnancy-specific beta-1-glycoprotein 1; Short=PS-beta-G-1; Short=PSBG-1; Short=Pregnancy-specific glycoprotein 1; AltName: Full=CD66 antigen-like family member F; AltName: Full=Fetal liver non-specific cross-reactive antigen 1/2; Short=FL-NCA-1/2; AltName: Full=PSG95; AltName: Full=Pregnancy-specific beta-1 glycoprotein C/D; Short=PS-beta-C/D; AltName: CD_antigen=CD66f; Flags: Precursor >gi|190636|gb|AAA36513.1| fetal liver non-specific cross-reactive antigen-2 precursor protein [Homo sapiens] >gi|306796|gb|AAA52601.1| pegnancy-specific beta-1-glycoprotein precursor [Homo sapiens] >gi|306798|gb|AAA52603.1| pregnancy-specific beta-glycoprotein d [Homo sapiens] >gi|3287451|gb|AAC25489.1| PBGD_HUMAN [Homo sapiens] >gi|34849465|gb|AAH58285.1| PSG1 protein [Homo sapiens] >gi|119577561|gb|EAW57157.1| pregnancy specific beta-1-glycoprotein 1, isoform CRA_d [Homo sapiens] 100 0 sp|P11464|PSG1_HUMAN Pregnancy-specific beta-1-glycoprotein 1 OS=Homo sapiens GN=PSG1 PE=2 SV=1 100 1.00E-53 Q9UMI0 Q9UMI0_HUMAN DHFRP2 protein (Fragment) OS=Homo sapiens GN=DHFRP2 PE=2 SV=1 - - - - - - - K06500|1|0.0|822|hsa:5669|pregnancy specific beta-1-glycoprotein GO:0006952//defense response;GO:0007565//female pregnancy - GO:0005576//extracellular region 352 sp|Q15063|POSTN_HUMAN Periostin OS=Homo sapiens GN=POSTN PE=1 SV=2 >tr|A0A024RDS2|A0A024RDS2_HUMAN Periostin, osteoblast specific factor, isoform CRA_c OS=Homo sapiens GN=POSTN PE=4 SV=1 115177 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGSTFKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETITEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ 6078 42 - 266 10 29 2 3.185 2.233 2.69 5 5 5 * * * 2.702666667 0.476126384 sp|Q15063|POSTN_HUMAN 100 5.00E-24 gi|166343767|gb|ABY86631.1| periostin isoform thy4 [Homo sapiens] 100 0 sp|Q15063|POSTN_HUMAN Periostin OS=Homo sapiens GN=POSTN PE=1 SV=2 100 5.00E-157 F5H570 F5H570_HUMAN Periostin OS=Homo sapiens GN=POSTN PE=4 SV=1 DR0399 84.3 9.00E-16 COG2335 Secreted and surface protein containing fasciclin-like repeats M Cell wall/membrane/envelope biogenesis ; - GO:0008593//regulation of Notch signaling pathway;GO:0001501//skeletal system development;GO:0009888//tissue development;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization GO:0008201//heparin binding GO:0005578//proteinaceous extracellular matrix 353 sp|P13667|PDIA4_HUMAN Protein disulfide-isomerase A4 OS=Homo sapiens GN=PDIA4 PE=1 SV=2 >tr|A0A090N8Y2|A0A090N8Y2_HUMAN Protein disulfide isomerase related protein (Calcium-binding protein, intestinal-related) OS=Homo sapiens GN=ERP70 PE=4 SV=1 93307 MRPRKAFLLLLLLGLVQLLAVAGAEGPDEDSSNRENAIEDEEEEEEEDDDEEEDDLEVKEENGVLVLNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILKKGQAVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFRKGRPYDYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVIIIGVFKGESDPAYQQYQDAANNLREDYKFHHTFSTEIAKFLKVSQGQLVVMQPEKFQSKYEPRSHMMDVQGSTQDSAIKDFVLKYALPLVGHRKVSNDAKRYTRRPLVVVYYSVDFSFDYRAATQFWRSKVLEVAKDFPEYTFAIADEEDYAGEVKDLGLSESGEDVNAAILDESGKKFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHATKLSRTKEEL 230 19.7 - 15 15 9 9 0.998 0.901 1.818 8 8 8 - - * 1.239 0.503768796 sp|P13667|PDIA4_HUMAN 100 0 gi|4758304|ref|NP_004902.1| protein disulfide-isomerase A4 precursor [Homo sapiens] >gi|119530|sp|P13667.2|PDIA4_HUMAN RecName: Full=Protein disulfide-isomerase A4; AltName: Full=Endoplasmic reticulum resident protein 70; Short=ER protein 70; Short=ERp70; AltName: Full=Endoplasmic reticulum resident protein 72; Short=ER protein 72; Short=ERp-72; Short=ERp72; Flags: Precursor >gi|181508|gb|AAA58460.1| protein disulfide isomerase-related protein [Homo sapiens] >gi|12653313|gb|AAH00425.1| Protein disulfide isomerase family A, member 4 [Homo sapiens] >gi|12804951|gb|AAH01928.1| Protein disulfide isomerase family A, member 4 [Homo sapiens] >gi|13623481|gb|AAH06344.1| Protein disulfide isomerase family A, member 4 [Homo sapiens] >gi|15079928|gb|AAH11754.1| Protein disulfide isomerase family A, member 4 [Homo sapiens] >gi|51105825|gb|EAL24425.1| protein disulfide isomerase related protein (calcium-binding protein, intestinal-related) [Homo sapiens] >gi|119600471|gb|EAW80065.1| protein disulfide isomerase family A, member 4, isoform CRA_a [Homo sapiens] >gi|119600472|gb|EAW80066.1| protein disulfide isomerase family A, member 4, isoform CRA_a [Homo sapiens] 100 0 sp|P13667|PDIA4_HUMAN Protein disulfide-isomerase A4 OS=Homo sapiens GN=PDIA4 PE=1 SV=2 98.91 0 H2QVK7 H2QVK7_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000155660 PE=3 SV=1 SPAC1F5.02 262 1.00E-69 COG0526 Thiol-disulfide isomerase and thioredoxins OC Posttranslational modification, protein turnover, chaperones ; Energy production and conversion ; K09582|1|0.0|1187|hsa:9601|protein disulfide-isomerase A4 [EC:5.3.4.1] GO:0045454//cell redox homeostasis;GO:0006662//glycerol ether metabolic process;GO:0009306//protein secretion GO:0009055//electron carrier activity;GO:0005515//protein binding;GO:0003756//protein disulfide isomerase activity;GO:0015035//protein disulfide oxidoreductase activity GO:0005788//endoplasmic reticulum lumen;GO:0042470//melanosome 354 tr|A0A024RC87|A0A024RC87_HUMAN Ribonuclease/angiogenin inhibitor 1, isoform CRA_a OS=Homo sapiens GN=RNH1 PE=4 SV=1 56381 MSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEARCKDISSALRVNPALAELNLRSNELGDVGVHCVLQGLQTPSCKIQKLSLQNCCLTGAGCGVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLASVLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRDLCGIVASKASLRELALGSNKLGDVGMAELCPGLLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEGARLLCETLLEPGCQLESLWVKSCSFTAACCSHFSSVLAQNRFLLELQISNNRLEDAGVRELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAATLLANHSLRELDLSNNCLGDAGILQLVESVRQPGCLLEQLVLYDIYWSEEMEDRLQALEKDKPSLRVIS 222 11.8 1 14 14 4 4 0.693 0.64 0.78 8 8 8 * * * 0.704333333 0.070684746 tr|A0A024RC87|A0A024RC87_HUMAN 100 0 gi|119622740|gb|EAX02335.1| ribonuclease/angiogenin inhibitor 1, isoform CRA_c [Homo sapiens] 100 0 sp|P13489|RINI_HUMAN Ribonuclease inhibitor OS=Homo sapiens GN=RNH1 PE=1 SV=2 100 2.00E-102 E9PIM9 E9PIM9_HUMAN Ribonuclease inhibitor (Fragment) OS=Homo sapiens GN=RNH1 PE=4 SV=1 - - - - - - - K12800|1|1e-55|218|acs:100552241|NACHT, LRR and PYD domains-containing protein 3 GO:0006264//mitochondrial DNA replication;GO:0006402//mRNA catabolic process;GO:0045765//regulation of angiogenesis GO:0003723//RNA binding;GO:0008428//ribonuclease inhibitor activity;GO:0000287//magnesium ion binding;GO:0004523//ribonuclease H activity;GO:0042803//protein homodimerization activity GO:0032311//angiogenin-PRI complex;GO:0005739//mitochondrion;GO:0005634//nucleus 355 tr|A8K0T9|A8K0T9_HUMAN cDNA FLJ75422, highly similar to Homo sapiens capping protein (actin filament) muscle Z-line, alpha 1, mRNA OS=Homo sapiens PE=2 SV=1 39448 MADFDDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLRDGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEADGGLKSWRESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSLTVSNEAQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA 195 15.7 1 11 7 3 2 0.821 0.654 0.705 5 5 5 - - - 0.726666667 0.085582319 tr|A8K0T9|A8K0T9_HUMAN 100 1.00E-159 gi|158260331|dbj|BAF82343.1| unnamed protein product [Homo sapiens] 99.65 9.00E-161 sp|P52907|CAZA1_HUMAN F-actin-capping protein subunit alpha-1 OS=Homo sapiens GN=CAPZA1 PE=1 SV=3 100 5.00E-159 A8K0T9 A8K0T9_HUMAN cDNA FLJ75422, highly similar to Homo sapiens capping protein (actin filament) muscle Z-line, alpha 1, mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K10364|1|9e-161|566|hsa:829|capping protein (actin filament) muscle Z-line, alpha GO:0045087//innate immune response;GO:0006928//cellular component movement;GO:0051693//actin filament capping;GO:0007596//blood coagulation GO:0003779//actin binding GO:0005829//cytosol;GO:0030863//cortical cytoskeleton;GO:0071203//WASH complex;GO:0008290//F-actin capping protein complex;GO:0005576//extracellular region;GO:0016020//membrane 356 tr|B2R8Z8|B2R8Z8_HUMAN cDNA, FLJ94136, highly similar to Homo sapiens synaptotagmin binding, cytoplasmic RNA interacting protein (SYNCRIP), mRNA OS=Homo sapiens PE=2 SV=1 84389 MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAKKLDEIYVAGLVAHSDLDERAIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSGNYGYKSENQEFYQDTFGQQWK 231 15.1 3 14 8 8 4 0.718 0.912 0.987 6 7 6 - - - 0.872333333 0.138817626 tr|B2R8Z8|B2R8Z8_HUMAN 100 1.00E-28 gi|194216234|ref|XP_001915169.1| PREDICTED: heterogeneous nuclear ribonucleoprotein Q isoform 1 [Equus caballus] 100 2.00E-29 sp|O60506|HNRPQ_HUMAN Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens GN=SYNCRIP PE=1 SV=2 100 1.00E-27 F6SYR7 F6SYR7_HORSE Uncharacterized protein OS=Equus caballus GN=SYNCRIP PE=4 SV=1 - - - - - - - K13160|1|0.0|882|ptr:462866|heterogeneous nuclear ribonucleoprotein Q GO:0070934//CRD-mediated mRNA stabilization;GO:0000398//mRNA splicing, via spliceosome;GO:0019048//virus-host interaction GO:0008143//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding GO:0070937//CRD-mediated mRNA stability complex;GO:0071204//histone pre-mRNA 3'end processing complex;GO:0071013//catalytic step 2 spliceosome;GO:0005654//nucleoplasm;GO:0005783//endoplasmic reticulum 357 tr|A0A087WT59|A0A087WT59_HUMAN Transthyretin OS=Homo sapiens GN=TTR PE=3 SV=1 23099 MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVSIQTFESFETDGCHGNRIQTCSSWSELQTSGFHQNVDVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE 99 14.1 4 4 4 2 2 0.759 1.632 1.09 4 4 3 - - - 1.160333333 0.44072932 tr|A0A087WT59|A0A087WT59_HUMAN 100 1.00E-53 gi|119621670|gb|EAX01265.1| transthyretin (prealbumin, amyloidosis type I), isoform CRA_b [Homo sapiens] 79.46 1.00E-69 sp|P02766|TTHY_HUMAN Transthyretin OS=Homo sapiens GN=TTR PE=1 SV=1 97.73 4.00E-17 Q53WY6 Q53WY6_HUMAN Transthyretin (Fragment) OS=Homo sapiens GN=transthyretin/ TTR PE=2 SV=1 Cj0715 48.1 7.00E-06 COG2351 Transthyretin-like protein R General function prediction only ; K07127|1|1e-13|76.3|spu:589020|5-hydroxyisourate hydrolase [EC:3.5.2.17] - GO:0005515//protein binding GO:0005576//extracellular region 358 tr|G9K388|G9K388_HUMAN YWHAE/FAM22A fusion protein (Fragment) OS=Homo sapiens GN=YWHAE/FAM22A fusion PE=2 SV=1 47320 RADPAGAAAAMDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTLPSTPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVV 734 18 2 41 23 6 4 0.859 0.716 0.777 17 18 18 * * * 0.784 0.071756533 tr|G9K388|G9K388_HUMAN 100 0 gi|365927536|gb|AEX07732.1| YWHAE/FAM22A fusion protein, partial [Homo sapiens] 100 8.00E-135 sp|P62262|1433E_SHEEP 14-3-3 protein epsilon OS=Ovis aries GN=YWHAE PE=1 SV=1 100 2.00E-133 G3RKZ8 G3RKZ8_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=YWHAE PE=3 SV=1 YDR099w 378 7.00E-105 COG5040 14-3-3 family protein T Signal transduction mechanisms ; K06630|1|9e-135|480|gga:417554|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein GO:0001764//neuron migration;GO:0035308//negative regulation of protein dephosphorylation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0021766//hippocampus development;GO:0006605//protein targeting;GO:0021987//cerebral cortex development;GO:0019048//virus-host interaction;GO:0035329//hippo signaling cascade;GO:0055114//oxidation-reduction process;GO:0000086//G2/M transition of mitotic cell cycle GO:0042826//histone deacetylase binding;GO:0050815//phosphoserine binding;GO:0004497//monooxygenase activity;GO:0019904//protein domain specific binding;GO:0008426//protein kinase C inhibitor activity;GO:0032403//protein complex binding GO:0042470//melanosome;GO:0005829//cytosol;GO:0033267//axon part;GO:0005871//kinesin complex;GO:0005739//mitochondrion 359 tr|Q6FHU3|Q6FHU3_HUMAN PSME1 protein (Fragment) OS=Homo sapiens GN=PSME1 PE=2 SV=1 38292 MAMLRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTSLHTKLEGFHSQISKYFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKPRGETKGMIY 348 41 1 18 18 10 10 0.83 0.839 1.122 11 11 11 - - - 0.930333333 0.166049189 tr|Q6FHU3|Q6FHU3_HUMAN 100 1.00E-122 gi|49456277|emb|CAG46459.1| PSME1 [Homo sapiens] 99.6 4.00E-123 sp|Q06323|PSME1_HUMAN Proteasome activator complex subunit 1 OS=Homo sapiens GN=PSME1 PE=1 SV=1 100 5.00E-122 Q6FHU3 Q6FHU3_HUMAN PSME1 protein (Fragment) OS=Homo sapiens GN=PSME1 PE=2 SV=1 - - - - - - - K06696|1|4e-123|440|pon:100455818|proteasome activator subunit 1 (PA28 alpha) GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0016032//viral reproduction;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0000084//S phase of mitotic cell cycle;GO:0010950//positive regulation of endopeptidase activity;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0005515//protein binding;GO:0061133//endopeptidase activator activity GO:0005654//nucleoplasm;GO:0008537//proteasome activator complex;GO:0005829//cytosol 360 tr|D3DP13|D3DP13_HUMAN Fibrinogen beta chain, isoform CRA_e OS=Homo sapiens GN=FGB PE=4 SV=1 48076 MYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFPQQ 62 19.5 3 8 8 6 6 0.581 0.828 1.139 4 4 4 - - - 0.849333333 0.279611039 tr|D3DP13|D3DP13_HUMAN 100 0 gi|194383548|dbj|BAG64745.1| unnamed protein product [Homo sapiens] 100 0 sp|P02675|FIBB_HUMAN Fibrinogen beta chain OS=Homo sapiens GN=FGB PE=1 SV=2 100 1.00E-162 D6REL8 D6REL8_HUMAN Fibrinogen beta chain OS=Homo sapiens GN=FGB PE=4 SV=1 - - - - - - - K03904|1|0.0|726|hsa:2244|fibrinogen beta chain GO:0030168//platelet activation;GO:0051258//protein polymerization;GO:0007165//signal transduction;GO:0002576//platelet degranulation;GO:0051592//response to calcium ion GO:0030674//protein binding, bridging;GO:0051087//chaperone binding;GO:0043499//eukaryotic cell surface binding;GO:0005102//receptor binding GO:0009897//external side of plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0005938//cell cortex;GO:0005577//fibrinogen complex 361 sp|P02649|APOE_HUMAN Apolipoprotein E OS=Homo sapiens GN=APOE PE=1 SV=1 40505 MKVLWAALLVTFLAGCQAKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGTSAAPVPSDNH 215 30.9 - 33 33 10 10 0.642 2.247 1.509 9 7 6 * * * 1.466 0.803363554 sp|P02649|APOE_HUMAN 100 1.00E-111 gi|406822414|gb|AFS60672.1| apolipoprotein E, partial [Homo sapiens] 100 5.00E-159 sp|P02649|APOE_HUMAN Apolipoprotein E OS=Homo sapiens GN=APOE PE=1 SV=1 100 7.00E-113 H0Y7L5 H0Y7L5_HUMAN Apolipoprotein E (Fragment) OS=Homo sapiens GN=APOE PE=4 SV=1 - - - - - - - K04524|1|5e-159|560|hsa:348|apolipoprotein E GO:0006641//triglyceride metabolic process;GO:0014012//peripheral nervous system axon regeneration;GO:0010468//regulation of gene expression;GO:0050728//negative regulation of inflammatory response;GO:0006707//cholesterol catabolic process;GO:0007010//cytoskeleton organization;GO:0019934//cGMP-mediated signaling;GO:0010875//positive regulation of cholesterol efflux;GO:0007263//nitric oxide mediated signal transduction;GO:0043691//reverse cholesterol transport;GO:0051651//maintenance of location in cell;GO:0010544//negative regulation of platelet activation;GO:0042311//vasodilation;GO:0046907//intracellular transport;GO:0002021//response to dietary excess;GO:0045471//response to ethanol;GO:0034375//high-density lipoprotein particle remodeling;GO:0006874//cellular calcium ion homeostasis;GO:0007271//synaptic transmission, cholinergic;GO:0045541//negative regulation of cholesterol biosynthetic process;GO:0006898//receptor-mediated endocytosis;GO:0042632//cholesterol homeostasis;GO:0001937//negative regulation of endothelial cell proliferation;GO:0034384//high-density lipoprotein particle clearance;GO:0007568//aging;GO:0048844//artery morphogenesis;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0000302//response to reactive oxygen species;GO:0043407//negative regulation of MAP kinase activity;GO:0030516//regulation of axon extension;GO:0034447//very-low-density lipoprotein particle clearance;GO:0034380//high-density lipoprotein particle assembly;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0034382//chylomicron remnant clearance;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030828//positive regulation of cGMP biosynthetic process;GO:0042158//lipoprotein biosynthetic process;GO:0032488//Cdc42 protein signal transduction;GO:0071363//cellular response to growth factor stimulus;GO:0032805//positive regulation of low-density lipoprotein particle receptor catabolic process;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0010873//positive regulation of cholesterol esterification;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0034374//low-density lipoprotein particle remodeling;GO:0042159//lipoprotein catabolic process;GO:0033700//phospholipid efflux;GO:0048168//regulation of neuronal synaptic plasticity;GO:0006917//induction of apoptosis GO:0050750//low-density lipoprotein particle receptor binding;GO:0042803//protein homodimerization activity;GO:0016209//antioxidant activity;GO:0070326//very-low-density lipoprotein particle receptor binding;GO:0008201//heparin binding;GO:0005543//phospholipid binding;GO:0046911//metal chelating activity;GO:0001540//beta-amyloid binding;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0071813//lipoprotein particle binding;GO:0046982//protein heterodimerization activity;GO:0017127//cholesterol transporter activity;GO:0048156//tau protein binding GO:0031232//extrinsic to external side of plasma membrane;GO:0034364//high-density lipoprotein particle;GO:0042627//chylomicron;GO:0034363//intermediate-density lipoprotein particle;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0034362//low-density lipoprotein particle;GO:0030425//dendrite;GO:0005874//microtubule;GO:0034361//very-low-density lipoprotein particle;GO:0043025//neuronal cell body;GO:0005770//late endosome 362 tr|A0A024R962|A0A024R962_HUMAN HCG40889, isoform CRA_b OS=Homo sapiens GN=hCG_40889 PE=4 SV=1 168295 MRLLAKIICLMLWAICVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENGWSPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDGWSAQPTCIKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGLSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVDGEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGVWTQLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSSPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEKWSHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCINSRWTGRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTCAKR 828 20.3 1 51 51 18 18 1.527 2.186 1.977 28 28 27 * * * 1.896666667 0.336764507 tr|A0A024R962|A0A024R962_HUMAN 100 0 gi|62739188|ref|NP_001014975.1| complement factor H isoform b precursor [Homo sapiens] 99.92 0 sp|P08603|CFAH_HUMAN Complement factor H OS=Homo sapiens GN=CFH PE=1 SV=4 100 0 C9JYL1 C9JYL1_HUMAN Complement factor H OS=Homo sapiens GN=CFH PE=4 SV=2 - - - - - - - K04004|1|0.0|2517|hsa:3075|complement factor H GO:0006957//complement activation, alternative pathway;GO:0030449//regulation of complement activation - GO:0005615//extracellular space 363 sp|O43175|SERA_HUMAN D-3-phosphoglycerate dehydrogenase OS=Homo sapiens GN=PHGDH PE=1 SV=4 65569 MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQGTSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGECLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPTMIGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF 60 6.2 - 3 3 3 3 1.513 1.043 1.205 2 2 2 - - - 1.253666667 0.23874952 sp|O43175|SERA_HUMAN 100 0 gi|5771521|gb|AAD51414.1|AF171236_1 3-phosphoglycerate dehydrogenase [Homo sapiens] 100 0 sp|O43175|SERA_HUMAN D-3-phosphoglycerate dehydrogenase OS=Homo sapiens GN=PHGDH PE=1 SV=4 100 0 Q9UMY2 Q9UMY2_HUMAN 3-phosphoglycerate dehydrogenase (Fragment) OS=Homo sapiens GN=PGDH3 PE=2 SV=1 MJ1018 350 3.00E-96 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases HE Coenzyme transport and metabolism ; Amino acid transport and metabolism ; K00058|1|0.0|1027|hsa:26227|D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95] GO:0034641//cellular nitrogen compound metabolic process;GO:0007420//brain development;GO:0006564//L-serine biosynthetic process;GO:0055114//oxidation-reduction process GO:0051287//NAD binding;GO:0004617//phosphoglycerate dehydrogenase activity;GO:0009055//electron carrier activity GO:0005829//cytosol 364 tr|A0A024R884|A0A024R884_HUMAN Tenascin C (Hexabrachion), isoform CRA_a OS=Homo sapiens GN=TNC PE=4 SV=1 271649 MGAMTQLLAGVFLAFLALATEGGVLKKVIRHKRQSGVNATLPEENQPVVFNHVYNIKLPVGSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRINIPRRACGCAAAPDVKELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGRGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIRELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDLTGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNGDTTSGLYTIYLNGDKAQALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEGRRKRA 1631 14.9 2 81 81 23 23 2.412 2.962 3.811 53 51 51 * - * 3.061666667 0.704805174 tr|A0A024R884|A0A024R884_HUMAN 100 0 gi|119607840|gb|EAW87434.1| tenascin C (hexabrachion), isoform CRA_a [Homo sapiens] >gi|119607841|gb|EAW87435.1| tenascin C (hexabrachion), isoform CRA_a [Homo sapiens] 99.82 0 sp|P24821|TENA_HUMAN Tenascin OS=Homo sapiens GN=TNC PE=1 SV=3 99.86 0 Q4LE33 Q4LE33_HUMAN TNC variant protein (Fragment) OS=Homo sapiens GN=TNC variant protein PE=2 SV=1 - - - - - - - K06252|1|0.0|4453|hsa:3371|tenascin GO:0014012//peripheral nervous system axon regeneration;GO:0007528//neuromuscular junction development;GO:0060740//prostate gland epithelium morphogenesis;GO:0007162//negative regulation of cell adhesion;GO:0010628//positive regulation of gene expression;GO:0060739//mesenchymal-epithelial cell signaling involved in prostate gland development;GO:0007165//signal transduction;GO:0008284//positive regulation of cell proliferation GO:0045545//syndecan binding;GO:0005178//integrin binding GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005614//interstitial matrix 365 tr|G3V3D1|G3V3D1_HUMAN Epididymal secretory protein E1 (Fragment) OS=Homo sapiens GN=NPC2 PE=1 SV=1 28399 MRFLAATFLLLALSTAAQAEPVQFKDCGSVDGVIKEVNVSPCPTQPCQLSKGQSYSVNVTFTSNIQSKSSKAVVHGILMGVPVPFPIPEPDGCKSGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQDDKNQSLFCWEIPVQIVSLSGGFSSLSASLSSVHLANESAETLDSTSSSAASTTVTCSPMVSSDSLKRRCSVAETELRVAGSQWLSHVSF 381 27.1 6 16 16 4 4 1.364 1.569 1.098 13 14 14 * * - 1.343666667 0.236157433 tr|G3V3D1|G3V3D1_HUMAN 100 2.00E-71 gi|355778731|gb|EHH63767.1| hypothetical protein EGM_16801, partial [Macaca fascicularis] 100 3.00E-72 sp|P61918|NPC2_MACFA Epididymal secretory protein E1 OS=Macaca fascicularis GN=NPC2 PE=2 SV=1 100 8.00E-90 G3V3D1 G3V3D1_HUMAN Epididymal secretory protein E1 (Fragment) OS=Homo sapiens GN=NPC2 PE=4 SV=1 - - - - - - - K13443|1|3e-72|271|mcc:699881|Niemann-Pick C2 protein GO:0009615//response to virus;GO:0033344//cholesterol efflux;GO:0019747//regulation of isoprenoid metabolic process;GO:0046836//glycolipid transport;GO:0032367//intracellular cholesterol transport;GO:0015914//phospholipid transport;GO:0042632//cholesterol homeostasis;GO:0008203//cholesterol metabolic process GO:0019899//enzyme binding;GO:0015485//cholesterol binding GO:0005764//lysosome;GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum 366 tr|Q05BM8|Q05BM8_HUMAN Polypeptide N-acetylgalactosaminyltransferase OS=Homo sapiens GN=GALNT1 PE=2 SV=1 67472 MGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDIDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPDSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCNGSRSQQWLLRNVTLPEIF 66 6.4 2 4 4 3 3 2.456 1.701 1.303 2 2 2 - - - 1.82 0.585638967 tr|Q05BM8|Q05BM8_HUMAN 100 0 gi|116284114|gb|AAH38440.1| GALNT1 protein [Homo sapiens] 99.8 0 sp|Q10472|GALT1_HUMAN Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens GN=GALNT1 PE=1 SV=1 100 0 Q05BM8 Q05BM8_HUMAN GALNT1 protein OS=Homo sapiens GN=GALNT1 PE=2 SV=1 - - - - - - - K00710|1|0.0|1042|mcc:708930|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0018242//protein O-linked glycosylation via serine;GO:0018243//protein O-linked glycosylation via threonine;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing GO:0030145//manganese ion binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0030246//carbohydrate binding GO:0032580//Golgi cisterna membrane;GO:0016021//integral to membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005576//extracellular region 367 tr|F5GZ03|F5GZ03_HUMAN T-complex protein 1 subunit alpha (Fragment) OS=Homo sapiens GN=TCP1 PE=1 SV=1 29599 MEGPLSVFGDRSTGETIRSQNGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYL 88 10 4 4 4 2 2 0.724 0.671 0.542 3 3 3 - - - 0.645666667 0.093607336 tr|F5GZ03|F5GZ03_HUMAN 100 2.00E-111 gi|75076024|sp|Q4R5G2.1|TCPA_MACFA RecName: Full=T-complex protein 1 subunit alpha; Short=TCP-1-alpha; AltName: Full=CCT-alpha 100 4.00E-112 sp|P17987|TCPA_HUMAN T-complex protein 1 subunit alpha OS=Homo sapiens GN=TCP1 PE=1 SV=1 100 9.00E-111 G3RDV8 G3RDV8_GORGO T-complex protein 1 subunit alpha (Fragment) OS=Gorilla gorilla gorilla PE=3 SV=1 SPBC12D12.03 283 2.00E-76 COG0459 Chaperonin GroEL (HSP60 family) O Posttranslational modification, protein turnover, chaperones ; K09493|1|3e-112|404|ptr:739754|T-complex protein 1 subunit alpha GO:0051084//'de novo' posttranslational protein folding;GO:0007021//tubulin complex assembly GO:0005524//ATP binding;GO:0051082//unfolded protein binding GO:0030054//cell junction;GO:0005730//nucleolus;GO:0005874//microtubule;GO:0005832//chaperonin-containing T-complex;GO:0005720//nuclear heterochromatin;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0000242//pericentriolar material 368 sp|P26641|EF1G_HUMAN Elongation factor 1-gamma OS=Homo sapiens GN=EEF1G PE=1 SV=3 >tr|Q53YD7|Q53YD7_HUMAN EEF1G protein OS=Homo sapiens GN=EEF1G PE=2 SV=1 60468 MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTPRKEKGSREEKQKPQAERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYSEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEGAFQHVGKAFNQGKIFK 178 19.9 - 17 17 8 8 0.77 0.767 0.8 5 5 5 - - * 0.779 0.018248288 sp|P26641|EF1G_HUMAN 100 0 gi|189597|gb|AAC18414.1| pancreatic tumor-related protein [Homo sapiens] 100 0 sp|P26641|EF1G_HUMAN Elongation factor 1-gamma OS=Homo sapiens GN=EEF1G PE=1 SV=3 100 8.00E-14 E7EMT2 E7EMT2_HUMAN Uncharacterized protein OS=Homo sapiens PE=4 SV=2 SPAC29A4.02c 206 5.00E-53 COG0625 Glutathione S-transferase O Posttranslational modification, protein turnover, chaperones ; K03233|1|0.0|851|hsa:1937|elongation factor 1-gamma GO:0009615//response to virus;GO:0006414//translational elongation GO:0003746//translation elongation factor activity;GO:0005515//protein binding GO:0005853//eukaryotic translation elongation factor 1 complex;GO:0005829//cytosol 369 tr|H0YA68|H0YA68_HUMAN Alpha-mannosidase (Fragment) OS=Homo sapiens GN=MAN2B2 PE=3 SV=1 112407 XQLCWLPLLAPLLLLRPPGVQSAGPIRAFVVPHSHMDVGWVYTVQESMRAYAANVYTSVVEELARGQQRRFIAVEQEFFRLWWDGVASDQQKYQVRQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGIRPQFSWHVDPFGASATTPTLFALAGFNAHLGSRIDYDLKAAMQEARGLQFVWRGSPSLSERQEIFTHIMDQYSYCTPSHIPFSNRSGFYWNGVAVFPKPPQDGVYPNMSEPVTPANINLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNASVQFANMDPLLDHINSHAAELGVSVQYATLGDYFRALHALNVTWRVRDHHDFLPYSTEPFQAWTGFYTSRSSLKGLARRASALLYAGESMFTRYLWPAPRGHLDPTWALQQLQQLRWAVSEVQHHDAITGTESPKVRDMYATHLASGMLGMRKLMASIVLDELQPQAPMAASSDAGPAGHFASVYNPLAWTVTTIVTLTVGFPGVRVTDEAGHPVPSQIQNSTETPSAYDLLILTTIPGLSYRHYNIRPTAGAQEGTQEPAATVASTLQFGRRLRRRTSHAGRYLVPVANDCYIVLLDQDTNLMHSIWERQSNRTVRVTQEFLEYHVNGDVKQGPISDNYLFTPGKAAVPAWEAVEMEIVAGQLVTEIRQYFYRNMTAQNYTYAIRSRLTHVPQGHDGELLCHRIEQEYQAGPLELNREAVLRTSTNLNSQQVIYSDNNGYQMQRRPYVSYVNNSIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLNDTSVVHPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGPQQQEAVTLPPNLHLQILSIPGWRYSSNHTEHSQNLRKGHRGEAQADLRRVLLRLYHLYEVGEDPVLSQPVTVNLEVNFPTPIQTISQGSKP 62 4.9 4 5 5 4 4 1.431 0.672 1.447 3 3 3 - - - 1.183333333 0.442899913 tr|H0YA68|H0YA68_HUMAN 100 3.00E-151 gi|116283826|gb|AAH36836.1| MAN2B2 protein [Homo sapiens] 100 0 sp|Q9Y2E5|MA2B2_HUMAN Epididymis-specific alpha-mannosidase OS=Homo sapiens GN=MAN2B2 PE=1 SV=4 100 0 H0YA68 H0YA68_HUMAN Epididymis-specific alpha-mannosidase (Fragment) OS=Homo sapiens GN=MAN2B2 PE=4 SV=1 MT0676 57.8 1.00E-07 COG0383 Alpha-mannosidase G Carbohydrate transport and metabolism ; K12312|1|0.0|1820|hsa:23324|epididymis-specific alpha-mannosidase [EC:3.2.1.24] GO:0006013//mannose metabolic process GO:0030246//carbohydrate binding;GO:0004559//alpha-mannosidase activity;GO:0008270//zinc ion binding GO:0005576//extracellular region 370 sp|Q9NR99|MXRA5_HUMAN Matrix-remodeling-associated protein 5 OS=Homo sapiens GN=MXRA5 PE=2 SV=3 363346 MPKRAHWGALSVVLILLWGHPRVALACPHPCACYVPSEVHCTFRSLASVPAGIAKHVERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLRVITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTFLDYFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYLQGNPWTCDCEMRWFLEWDAKSRGILKCKKDKAYEGGQLCAMCFSPKKLYKHEIHKLKDMTCLKPSIESPLRQNRSRSIEEEQEQEEDGGSQLILEKFQLPQWSISLNMTDEHGNMVNLVCDIKKPMDVYKIHLNQTDPPDIDINATVALDFECPMTRENYEKLWKLIAYYSEVPVKLHRELMLSKDPRVSYQYRQDADEEALYYTGVRAQILAEPEWVMQPSIDIQLNRRQSTAKKVLLSYYTQYSQTISTKDTRQARGRSWVMIEPSGAVQRDQTVLEGGPCQLSCNVKASESPSIFWVLPDGSILKAPMDDPDSKFSILSSGWLRIKSMEPSDSGLYQCIAQVRDEMDRMVYRVLVQSPSTQPAEKDTVTIGKNPGESVTLPCNALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQGADHFTVGITVTKKGSGLPSKRGRRPGAKALSRVREDIVEDEGGSGMGDEENTSRRLLHPKDQEVFLKTKDDAINGDKKAKKGRRKLKLWKHSEKEPETNVAEGRRVFESRRRINMANKQINPERWADILAKVRGKNLPKGTEVPPLIKTTSPPSLSLEVTPPFPAISPPSASPVQTVTSAEESSADVPLLGEEEHVLGTISSASMGLEHNHNGVILVEPEVTSTPLEEVVDDLSEKTEEITSTEGDLKGTAAPTLISEPYEPSPTLHTLDTVYEKPTHEETATEGWSAADVGSSPEPTSSEYEPPLDAVSLAESEPMQYFDPDLETKSQPDEDKMKEDTFAHLTPTPTIWVNDSSTSQLFEDSTIGEPGVPGQSHLQGLTDNIHLVKSSLSTQDTLLIKKGMKEMSQTLQGGNMLEGDPTHSRSSESEGQESKSITLPDSTLGIMSSMSPVKKPAETTVGTLLDKDTTTATTTPRQKVAPSSTMSTHPSRRRPNGRRRLRPNKFRHRHKQTPPTTFAPSETFSTQPTQAPDIKISSQVESSLVPTAWVDNTVNTPKQLEMEKNAEPTSKGTPRRKHGKRPNKHRYTPSTVSSRASGSKPSPSPENKHRNIVTPSSETILLPRTVSLKTEGPYDSLDYMTTTRKIYSSYPKVQETLPVTYKPTSDGKEIKDDVATNVDKHKSDILVTGESITNAIPTSRSLVSTMGEFKEESSPVGFPGTPTWNPSRTAQPGRLQTGIPVTTSGENLTDPPLLKELEDVDFTSEFLSSLTVSTPFHQEEAGSSTTLSSIKVEVASSQAETTTLDQDHLETTVAILLSETRPQNHTPTAARMKEPASSSPSTILMSLGQTTTTKPALPSPRISQASRDSKENVFLNYVGNPETEATPVNNEGTQHMSGPNELSTPSSDQDAFNLSTKLELEKQVFGSRSLPRGPDSQRQDGRVHASHQLTRVPAKPILPTATVRLPEMSTQSASRYFVTSQSPRHWTNKPEITTYPSGALPENKQFTTPRLSSTTIPLPLHMSKPSIPSKFTDRRTDQFNGYSKVFGNNNIPEARNPVGKPPSPRIPHYSNGRLPFFTNKTLSFPQLGVTRRPQIPTSPAPVMRERKVIPGSYNRIHSHSTFHLDFGPPAPPLLHTPQTTGSPSTNLQNIPMVSSTQSSISFITSSVQSSGSFHQSSSKFFAGGPPASKFWSLGEKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNGTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVEGRITLHENRTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILGSDSKTTYIHVF 1618 11.4 - 118 118 27 27 2.522 4.176 3.975 61 60 56 - * * 3.557666667 0.902526639 sp|Q9NR99|MXRA5_HUMAN 100 0 gi|139948432|ref|NP_056234.2| matrix-remodeling-associated protein 5 precursor [Homo sapiens] >gi|317373412|sp|Q9NR99.3|MXRA5_HUMAN RecName: Full=Matrix-remodeling-associated protein 5; AltName: Full=Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan; Short=Adlican; Flags: Precursor 100 0 sp|Q9NR99|MXRA5_HUMAN Matrix-remodeling-associated protein 5 OS=Homo sapiens GN=MXRA5 PE=2 SV=3 99.68 0 H2QY93 H2QY93_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000101825 PE=4 SV=1 alr0124_1 54.7 2.00E-06 COG4886 Leucine-rich repeat (LRR) protein S Function unknown ; K06255|1|3e-70|269|xtr:100494785|heparan sulfate proteoglycan 2 (perlecan) - - GO:0005576//extracellular region 371 tr|B3KS70|B3KS70_HUMAN cDNA FLJ35660 fis, clone SPLEN2017538, highly similar to Dickkopf-related protein 3 OS=Homo sapiens PE=2 SV=1 35610 MEDTQHKLRSAVEEMEAEEAAAKASSEVNLANLPPSYHNETNTDTKVGNNTIHVHREIHKITNNQTGQMVFSETVITSVGDEEGRRSHECIIDEDCGPSMYCQFASFQYTCQPCRGQRMLCTRDSECCGDQLCVWGHCTKMATRGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPASRLLDLITWELEPDGALDRCPCASGLLCQPHSHSLVYVCKPTFVGSRDQDGEILLPREVPDEYEVGSFMEEVRQELEDLERSLTEEMALGEPAAAAAALLGGEEI 1145 21.2 5 36 36 4 4 0.84 0.714 0.756 32 33 31 * - - 0.77 0.06415606 tr|B3KS70|B3KS70_HUMAN 100 6.00E-146 gi|193787426|dbj|BAG52632.1| unnamed protein product [Homo sapiens] 100 2.00E-147 sp|Q9UBP4|DKK3_HUMAN Dickkopf-related protein 3 OS=Homo sapiens GN=DKK3 PE=1 SV=2 100 2.00E-145 B3KS70 B3KS70_HUMAN cDNA FLJ35660 fis, clone SPLEN2017538, highly similar to Dickkopf-related protein 3 OS=Homo sapiens PE=2 SV=1 - - - - - - - K02165|1|5e-08|58.9|hsa:27121|dickkopf GO:2000065//negative regulation of cortisol biosynthetic process;GO:0090090//negative regulation of canonical Wnt receptor signaling pathway;GO:0032348//negative regulation of aldosterone biosynthetic process;GO:0009653//anatomical structure morphogenesis;GO:0045892//negative regulation of transcription, DNA-dependent;GO:0030325//adrenal gland development - GO:0005615//extracellular space 372 tr|J3K000|J3K000_HUMAN PEPD protein OS=Homo sapiens GN=PEPD PE=2 SV=1 61429 MAAATGPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGSIVVLQGGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGKSTLFVPRLPASHATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLTLRGVNTDSGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFFNREVLQRFRGFGGVRIEEDVVVTDSGIELLTCVPRTVEEIEACMAGCDKAFTPFSGPK 213 8.1 1 16 16 4 4 1.203 0.818 1.041 6 7 6 - - - 1.020666667 0.193303733 tr|J3K000|J3K000_HUMAN 100 0 gi|112491419|pdb|2IW2|A Chain A, Crystal Structure Of Human Prolidase >gi|112491420|pdb|2IW2|B Chain B, Crystal Structure Of Human Prolidase >gi|134105229|pdb|2OKN|A Chain A, Crystal Strcture Of Human Prolidase >gi|134105230|pdb|2OKN|B Chain B, Crystal Strcture Of Human Prolidase 99.8 0 sp|P12955|PEPD_HUMAN Xaa-Pro dipeptidase OS=Homo sapiens GN=PEPD PE=1 SV=3 100 2.00E-31 E9PCE8 E9PCE8_HUMAN Xaa-Pro dipeptidase OS=Homo sapiens GN=PEPD PE=3 SV=1 YFR006w 234 3.00E-61 COG0006 Xaa-Pro aminopeptidase E Amino acid transport and metabolism ; K14213|1|0.0|1025|hsa:5184|Xaa-Pro dipeptidase [EC:3.4.13.9] GO:0006520//cellular amino acid metabolic process;GO:0030574//collagen catabolic process;GO:0006508//proteolysis GO:0030145//manganese ion binding;GO:0004181//metallocarboxypeptidase activity;GO:0004177//aminopeptidase activity;GO:0016805//dipeptidase activity - 373 tr|G3XAP6|G3XAP6_HUMAN Cartilage oligomeric matrix protein OS=Homo sapiens GN=COMP PE=4 SV=1 88600 MLRELQETNAALQDVRELLRQQVREITFLKNTVMECDACGMQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQEDADRDGVGDVCQDDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLDPEGDAQIDPNWVVLNQGREIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQMEQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTESQVRLLWKDPRNVGWKDKKSYRWFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGGRLGVFCFSQENIIWANLRYRCNDTIPEDYETHQLRQA 377 14.5 4 14 14 7 7 1.357 1.786 1.486 8 8 6 * * * 1.543 0.220106792 tr|G3XAP6|G3XAP6_HUMAN 100 0 gi|40217843|ref|NP_000086.2| cartilage oligomeric matrix protein precursor [Homo sapiens] >gi|209572601|sp|P49747.2|COMP_HUMAN RecName: Full=Cartilage oligomeric matrix protein; Short=COMP; AltName: Full=Thrombospondin-5; Short=TSP5; Flags: Precursor >gi|84570077|gb|AAI10848.1| Cartilage oligomeric matrix protein [Homo sapiens] >gi|115527966|gb|AAI25093.1| Cartilage oligomeric matrix protein [Homo sapiens] >gi|119605143|gb|EAW84737.1| cartilage oligomeric matrix protein, isoform CRA_c [Homo sapiens] 100 0 sp|P49747|COMP_HUMAN Cartilage oligomeric matrix protein OS=Homo sapiens GN=COMP PE=1 SV=2 100 0 G3XAP6 G3XAP6_HUMAN Cartilage oligomeric matrix protein OS=Homo sapiens GN=COMP PE=4 SV=1 - - - - - - - K04659|1|0.0|1276|hsa:1311|thrombospondin GO:0060173//limb development;GO:0007155//cell adhesion;GO:0003417//growth plate cartilage development GO:0008201//heparin binding;GO:0005518//collagen binding;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding;GO:0043395//heparan sulfate proteoglycan binding GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 374 sp|Q9BRA2|TXD17_HUMAN Thioredoxin domain-containing protein 17 OS=Homo sapiens GN=TXNDC17 PE=1 SV=1 17563 MARYEEVSVSGFEEFHRAVEQHNGKTIFAYFTGSKDAGGKSWCPDCVQAEPVVREGLKHISEGCVFIYCQVGEKPYWKDPNNDFRKNLKVTAVPTLLKYGTPQKLVESECLQANLVEMLFSED 99 26.8 - 7 7 3 3 0.741 0.694 0.923 5 5 5 - * - 0.786 0.120950403 sp|Q9BRA2|TXD17_HUMAN 100 3.00E-68 gi|14249348|ref|NP_116120.1| thioredoxin domain-containing protein 17 [Homo sapiens] >gi|74732856|sp|Q9BRA2.1|TXD17_HUMAN RecName: Full=Thioredoxin domain-containing protein 17; AltName: Full=14 kDa thioredoxin-related protein; Short=TRP14; AltName: Full=Protein 42-9-9; AltName: Full=Thioredoxin-like protein 5 >gi|55670733|pdb|1WOU|A Chain A, Crystal Structure Of Human Trp14 >gi|13623581|gb|AAH06405.1| Thioredoxin domain containing 17 [Homo sapiens] >gi|119610708|gb|EAW90302.1| thioredoxin-like 5 [Homo sapiens] 100 3.00E-69 sp|Q9BRA2|TXD17_HUMAN Thioredoxin domain-containing protein 17 OS=Homo sapiens GN=TXNDC17 PE=1 SV=1 100 1.00E-67 G3QKM5 G3QKM5_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=TXNDC17 PE=4 SV=1 - - - - - - - K00685|1|2e-22|103|tsp:Tsp_00010|arginine-tRNA-protein transferase [EC:2.3.2.8]!K00771|2|5e-22|102|smm:Smp_128310.1|protein xylosyltransferase [EC:2.4.2.26] GO:0033209//tumor necrosis factor-mediated signaling pathway GO:0009055//electron carrier activity;GO:0005515//protein binding;GO:0047134//protein-disulfide reductase activity;GO:0004601//peroxidase activity GO:0005829//cytosol 375 tr|A0A0A0MSV6|A0A0A0MSV6_HUMAN Complement C1q subcomponent subunit B (Fragment) OS=Homo sapiens GN=C1QB PE=4 SV=1 29198 MKIPWGSIPVLMLLLLLGLIDISQAQLSCTGPPAIPGIPGIPGTPGPDGQPGTPGIKGEKGLPGLAGDHGEFGEKGDPGIPGNPGKVGPKGPMGPKGGPGAPGAPGPKGESGDYKATQKIAFSATRTINVPLRRDQTIRFDHVITNMNNNYEPRSGKFTCKVPGLYYFTYHASSRGNLCVNLMRGRERAQKVVTFCDYAYNTFQVTTGGMVLKLEQGENVFLQATDKNS 143 15.7 2 5 5 3 3 0.701 3.09 1.019 3 3 2 - * - 1.603333333 1.297271881 tr|A0A0A0MSV6|A0A0A0MSV6_HUMAN 100 1.00E-61 gi|38492827|pdb|1PK6|B Chain B, Globular Head Of The Complement System Protein C1q 100 8.00E-85 sp|P02746|C1QB_HUMAN Complement C1q subcomponent subunit B OS=Homo sapiens GN=C1QB PE=1 SV=3 100 2.00E-83 Q5T960 Q5T960_HUMAN Complement component 1, q subcomponent, B chain (Fragment) OS=Homo sapiens GN=C1QB PE=2 SV=2 - - - - - - - K03987|1|8e-85|313|hsa:713|complement C1q subcomponent subunit B GO:0006958//complement activation, classical pathway;GO:0045087//innate immune response;GO:0032502//developmental process GO:0005515//protein binding GO:0005576//extracellular region 376 tr|A0A024RAL1|A0A024RAL1_HUMAN Chondroitin sulfate proteoglycan 2 (Versican), isoform CRA_c OS=Homo sapiens GN=CSPG2 PE=4 SV=1 296390 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTETELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLATALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPTESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTILEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETELDVLLPTATSLPIPRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIPTLGQFERTQEEYEDKKHAGPSFQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNPPYYTDTTLAVSTFAKLSSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDSFKEIHVNIEATFKPSSEEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVEGTEILQDFQNKTDGQVSGEAIKMFPTIKTPEAGTVITTADEIELEGATQWPHSTSASATYGVEAGVVPWLSPQTSERPTLSSSPEINPETQAALIRGQDSTIAASEQQVAARILDSNDQATVNPVEFNTEVATPPFSLLETSNETDFLIGINEESVEGTAIYLPGPDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPPVVENAKTFGKMKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCMNPSAYQRTYSMKYFKNSSSAKDNSINTSKHDHRWSRRWQESRR 1117 4.4 - 46 46 9 9 1.424 1.447 1.48 24 30 28 * * * 1.450333333 0.028148416 tr|A0A024RAL1|A0A024RAL1_HUMAN 100 0 gi|221041250|dbj|BAH12302.1| unnamed protein product [Homo sapiens] 100 0 sp|P13611|CSPG2_HUMAN Versican core protein OS=Homo sapiens GN=VCAN PE=1 SV=3 100 0 D6RGZ6 D6RGZ6_HUMAN Versican core protein (Fragment) OS=Homo sapiens GN=VCAN PE=4 SV=1 - - - - - - - K06793|1|0.0|3785|pon:100442387|chondroitin sulfate proteoglycan 2 (versican) GO:0030207//chondroitin sulfate catabolic process;GO:0008037//cell recognition;GO:0031103//axon regeneration;GO:0008347//glial cell migration;GO:0005975//carbohydrate metabolic process;GO:0007507//heart development;GO:0007155//cell adhesion;GO:0030208//dermatan sulfate biosynthetic process;GO:0044281//small molecule metabolic process GO:0005509//calcium ion binding;GO:0005540//hyaluronic acid binding GO:0005796//Golgi lumen;GO:0043202//lysosomal lumen;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 377 sp|O95373|IPO7_HUMAN Importin-7 OS=Homo sapiens GN=IPO7 PE=1 SV=1 137178 MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN 69 2.2 - 2 2 2 2 0.751 0.883 0.962 2 2 2 * - - 0.865333333 0.106603627 sp|O95373|IPO7_HUMAN 100 0 gi|119588997|gb|EAW68591.1| importin 7, isoform CRA_a [Homo sapiens] 100 0 sp|O95373|IPO7_HUMAN Importin-7 OS=Homo sapiens GN=IPO7 PE=1 SV=1 100 0 B3KQG6 B3KQG6_HUMAN cDNA FLJ90427 fis, clone NT2RP3000481, highly similar to Importin-7 OS=Homo sapiens PE=2 SV=1 SPCC550.11 437 4.00E-122 COG5656 Importin, protein involved in nuclear import O Posttranslational modification, protein turnover, chaperones ; - GO:0006606//protein import into nucleus;GO:0007165//signal transduction;GO:0019048//virus-host interaction GO:0008565//protein transporter activity;GO:0005083//small GTPase regulator activity;GO:0008536//Ran GTPase binding;GO:0042393//histone binding GO:0005643//nuclear pore;GO:0005794//Golgi apparatus 378 tr|J3KQE5|J3KQE5_HUMAN GTP-binding nuclear protein Ran (Fragment) OS=Homo sapiens GN=RAN PE=1 SV=1 32807 RRRRLRLRRLNCASAIFPASVGRARRRFWKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL 146 14.5 3 6 6 3 3 1.032 0.892 0.831 5 6 6 - - - 0.918333333 0.103055001 tr|J3KQE5|J3KQE5_HUMAN 100 2.00E-95 gi|148687577|gb|EDL19524.1| mCG123446, isoform CRA_b [Mus musculus] 96.3 9.00E-120 sp|P62825|RAN_CANFA GTP-binding nuclear protein Ran OS=Canis familiaris GN=RAN PE=1 SV=3 100 5.00E-117 G1LC30 G1LC30_AILME Uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca PE=4 SV=1 ECU04g1560 175 6.00E-44 COG1100 GTPase SAR1 and related small G proteins R General function prediction only ; K07936|1|6e-120|429|mcc:709200|GTP-binding nuclear protein Ran GO:0034629//cellular protein complex localization;GO:0032092//positive regulation of protein binding;GO:0007052//mitotic spindle organization;GO:0030521//androgen receptor signaling pathway;GO:0051301//cell division;GO:0006611//protein export from nucleus;GO:0006184//GTP catabolic process;GO:0006259//DNA metabolic process;GO:0030036//actin cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction;GO:0007067//mitosis;GO:0019048//virus-host interaction;GO:0007286//spermatid development;GO:0019058//viral infectious cycle;GO:0045893//positive regulation of transcription, DNA-dependent;GO:0006606//protein import into nucleus;GO:0006405//RNA export from nucleus GO:0005525//GTP binding;GO:0019904//protein domain specific binding;GO:0003713//transcription coactivator activity;GO:0019003//GDP binding;GO:0003682//chromatin binding;GO:0003924//GTPase activity;GO:0050681//androgen receptor binding GO:0000785//chromatin;GO:0005654//nucleoplasm;GO:0042470//melanosome;GO:0005829//cytosol;GO:0005643//nuclear pore 379 tr|B3VL17|B3VL17_HUMAN Beta globin (Fragment) OS=Homo sapiens PE=3 SV=1 14272 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTXRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPEXFR 478 18.1 - 37 37 4 4 0.93 0.684 0.62 16 16 16 - * * 0.744666667 0.163662254 tr|B3VL17|B3VL17_HUMAN 100 2.00E-53 gi|193244921|gb|ACF16774.1| beta globin [Homo sapiens] 98.1 5.00E-55 sp|P68873|HBB_PANTR Hemoglobin subunit beta OS=Pan troglodytes GN=HBB PE=1 SV=2 100 7.00E-53 B3VL17 B3VL17_HUMAN Beta globin (Fragment) OS=Homo sapiens PE=3 SV=1 - - - - - - - K13823|1|5e-55|212|ptr:450978|hemoglobin subunit beta GO:0042744//hydrogen peroxide catabolic process;GO:0051291//protein heterooligomerization;GO:0010942//positive regulation of cell death;GO:0015701//bicarbonate transport;GO:0008217//regulation of blood pressure;GO:0015671//oxygen transport;GO:0070293//renal absorption;GO:0030185//nitric oxide transport;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0044281//small molecule metabolic process;GO:0050880//regulation of blood vessel size;GO:0007596//blood coagulation GO:0004601//peroxidase activity;GO:0030492//hemoglobin binding;GO:0005344//oxygen transporter activity;GO:0019825//oxygen binding;GO:0031720//haptoglobin binding;GO:0020037//heme binding;GO:0005506//iron ion binding GO:0031838//haptoglobin-hemoglobin complex;GO:0005833//hemoglobin complex 380 sp|Q06828|FMOD_HUMAN Fibromodulin OS=Homo sapiens GN=FMOD PE=1 SV=2 >tr|A0A024R971|A0A024R971_HUMAN Fibromodulin, isoform CRA_a OS=Homo sapiens GN=FMOD PE=4 SV=1 46840 MQWTSLLLLAGLFSLSQAQYEDDPHWWFHYLRSQQSTYYDPYDPYPYETYEPYPYGVDEGPAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI 80 5.6 - 7 7 2 2 5.575 3.543 5.828 3 3 3 - * * 4.982 1.252614466 sp|Q06828|FMOD_HUMAN 100 0 gi|71040111|ref|NP_002014.2| fibromodulin precursor [Homo sapiens] >gi|223590208|sp|Q06828.2|FMOD_HUMAN RecName: Full=Fibromodulin; Short=FM; AltName: Full=Collagen-binding 59 kDa protein; AltName: Full=Keratan sulfate proteoglycan fibromodulin; Short=KSPG fibromodulin; Flags: Precursor >gi|23271348|gb|AAH35281.1| Fibromodulin [Homo sapiens] >gi|119611883|gb|EAW91477.1| fibromodulin, isoform CRA_a [Homo sapiens] >gi|119611884|gb|EAW91478.1| fibromodulin, isoform CRA_a [Homo sapiens] 100 0 sp|Q06828|FMOD_HUMAN Fibromodulin OS=Homo sapiens GN=FMOD PE=1 SV=2 100 1.00E-40 H9FKF4 H9FKF4_MACMU Fibromodulin (Fragment) OS=Macaca mulatta GN=FMOD PE=2 SV=1 alr0124_1 87.4 3.00E-17 COG4886 Leucine-rich repeat (LRR) protein S Function unknown ; K08121|1|0.0|679|hsa:2331|fibromodulin GO:0042060//wound healing;GO:0042476//odontogenesis;GO:0007181//transforming growth factor beta receptor complex assembly;GO:0005975//carbohydrate metabolic process;GO:0042340//keratan sulfate catabolic process;GO:0044281//small molecule metabolic process;GO:0018146//keratan sulfate biosynthetic process - GO:0005796//Golgi lumen;GO:0043202//lysosomal lumen;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 381 sp|Q9Y678|COPG1_HUMAN Coatomer subunit gamma-1 OS=Homo sapiens GN=COPG1 PE=1 SV=1 115698 MLKKFDKKDEESGGGSNPFQHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHALGLLYHVRKNDRLAVNKMISKVTRHGLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTTNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKALNAGYILNGLTVSIPGLERALQQYTLEPSEKPFDLKSVPLATAPMAEQRTESTPITAVKQPEKVAATRQEIFQEQLAAVPEFRGLGPLFKSSPEPVALTESETEYVIRCTKHTFTNHMVFQFDCTNTLNDQTLENVTVQMEPTEAYEVLCYVPARSLPYNQPGTCYTLVALPKEDPTAVACTFSCMMKFTVKDCDPTTGETDDEGYEDEYVLEDLEVTVADHIQKVMKLNFEAAWDEVGDEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPDNKNTHTLLLAGVFRGGHDILVRSRLLLLDTVTMQVTARSLEELPVDIILASVG 211 10.6 - 10 10 7 7 1.27 1.109 0.833 8 6 8 * * - 1.070666667 0.221007541 sp|Q9Y678|COPG1_HUMAN 100 0 gi|32425777|gb|AAH20498.2| COPG protein, partial [Homo sapiens] 100 0 sp|Q9Y678|COPG1_HUMAN Coatomer subunit gamma-1 OS=Homo sapiens GN=COPG1 PE=1 SV=1 100 0 G3RE83 G3RE83_GORGO Coatomer subunit gamma OS=Gorilla gorilla gorilla GN=COPG PE=3 SV=1 SPAC57A7.10c 602 1.00E-171 COG5240 Vesicle coat complex COPI, gamma subunit U Intracellular trafficking, secretion, and vesicular transport ; K10300|1|1e-71|272|tgu:100221878|F-box protein, helicase, 18 [EC:3.6.4.12] GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0072384//organelle transport along microtubule;GO:0048205//COPI coating of Golgi vesicle;GO:0006886//intracellular protein transport;GO:0051683//establishment of Golgi localization GO:0005198//structural molecule activity GO:0030126//COPI vesicle coat;GO:0005829//cytosol;GO:0005634//nucleus 382 tr|B4DK28|B4DK28_HUMAN cDNA FLJ56000, highly similar to Carboxypeptidase-like protein X2 OS=Homo sapiens PE=2 SV=1 83099 MRTKSSEKAANDDHSVRVAREDVRESCPPLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNNYYHRRNEMTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISVEGINHDIRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTLSKTNMARIREIMEKFGKQPVSLPARRLKLRGRKRRQRG 213 15.9 2 15 11 8 7 1.445 1.254 1.877 6 7 7 * - - 1.525333333 0.319174456 tr|B4DK28|B4DK28_HUMAN 100 0 gi|223005864|ref|NP_937791.2| inactive carboxypeptidase-like protein X2 precursor [Homo sapiens] >gi|296439384|sp|Q8N436.3|CPXM2_HUMAN RecName: Full=Inactive carboxypeptidase-like protein X2; Flags: Precursor 100 0 sp|Q8N436|CPXM2_HUMAN Inactive carboxypeptidase-like protein X2 OS=Homo sapiens GN=CPXM2 PE=2 SV=3 100 0 Q658N0 Q658N0_HUMAN Putative uncharacterized protein DKFZp666J235 (Fragment) OS=Homo sapiens GN=DKFZp666J235 PE=2 SV=1 sll0236 52.4 3.00E-06 COG2866 Predicted carboxypeptidase E Amino acid transport and metabolism ; K08639|1|0.0|1281|hsa:119587|carboxypeptidase X2 GO:0007155//cell adhesion;GO:0006508//proteolysis GO:0004181//metallocarboxypeptidase activity;GO:0008270//zinc ion binding GO:0005615//extracellular space;GO:0031012//extracellular matrix 383 tr|H0YDJ9|H0YDJ9_HUMAN Tetraspanin (Fragment) OS=Homo sapiens GN=CD81 PE=1 SV=1 28340 GGSRWQRGFPQLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETLDCCGSSTLTALTTSVLKNNLCPSGSNIISNLFKEDCHQKIDDLFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY 99 19.1 6 2 2 2 2 1.016 0.53 0.997 2 2 2 - - - 0.847666667 0.275271381 tr|H0YDJ9|H0YDJ9_HUMAN 100 3.00E-93 gi|426366963|ref|XP_004050511.1| PREDICTED: CD81 antigen [Gorilla gorilla gorilla] 100 8.00E-94 sp|P60034|CD81_PANTR CD81 antigen OS=Pan troglodytes GN=CD81 PE=2 SV=1 100 6.00E-93 H2Q2W9 H2Q2W9_PANTR CD81 antigen (Fragment) OS=Pan troglodytes GN=CD81 PE=4 SV=1 - - - - - - - K06508|1|9e-94|342|ptr:449635|CD81 antigen GO:0043128//positive regulation of 1-phosphatidylinositol 4-kinase activity;GO:0009611//response to wounding;GO:0046718//viral entry into host cell;GO:0046813//virion attachment, binding of host cell surface receptor;GO:0050776//regulation of immune response;GO:0008284//positive regulation of cell proliferation;GO:0040008//regulation of growth;GO:0008104//protein localization;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0000187//activation of MAPK activity GO:0005515//protein binding GO:0001772//immunological synapse;GO:0005887//integral to plasma membrane;GO:0016324//apical plasma membrane 384 sp|P31949|S10AB_HUMAN Protein S100-A11 OS=Homo sapiens GN=S100A11 PE=1 SV=2 >tr|V9HWH9|V9HWH9_HUMAN Protein S100 OS=Homo sapiens GN=HEL-S-43 PE=2 SV=1 15193 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT 839 34.3 - 41 41 3 3 0.614 0.373 0.658 30 31 29 - - * 0.548333333 0.153428594 sp|P31949|S10AB_HUMAN 100 4.00E-56 gi|5032057|ref|NP_005611.1| protein S100-A11 [Homo sapiens] >gi|1710818|sp|P31949.2|S10AB_HUMAN RecName: Full=Protein S100-A11; AltName: Full=Calgizzarin; AltName: Full=Metastatic lymph node gene 70 protein; Short=MLN 70; AltName: Full=Protein S100-C; AltName: Full=S100 calcium-binding protein A11 >gi|560791|dbj|BAA07597.1| calgizzarin [Homo sapiens] >gi|951233|emb|CAA56492.1| MLN 70, S100 C [Homo sapiens] >gi|1020406|dbj|BAA08354.1| human S100C protein [Homo sapiens] >gi|2605598|dbj|BAA23325.1| calcium binding protein [Homo sapiens] >gi|12655117|gb|AAH01410.1| S100 calcium binding protein A11 [Homo sapiens] >gi|15680066|gb|AAH14354.1| S100 calcium binding protein A11 [Homo sapiens] >gi|32880167|gb|AAP88914.1| S100 calcium binding protein A11 (calgizzarin) [Homo sapiens] >gi|119573777|gb|EAW53392.1| S100 calcium binding protein A11 (calgizzarin) [Homo sapiens] 100 5.00E-57 sp|P31949|S10AB_HUMAN Protein S100-A11 OS=Homo sapiens GN=S100A11 PE=1 SV=2 100 2.00E-55 H2N5T5 H2N5T5_PONAB Uncharacterized protein OS=Pongo abelii GN=LOC100439774 PE=4 SV=1 - - - - - - - K10384|1|2e-11|67.8|cfa:483211|filaggrin GO:0008156//negative regulation of DNA replication;GO:0008285//negative regulation of cell proliferation;GO:0007165//signal transduction GO:0005509//calcium ion binding;GO:0044548//S100 protein binding;GO:0048306//calcium-dependent protein binding;GO:0042803//protein homodimerization activity GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005634//nucleus 385 tr|A0A0A0MR60|A0A0A0MR60_HUMAN Receptor-type tyrosine-protein phosphatase S OS=Homo sapiens GN=PTPRS PE=4 SV=1 190393 MAPTWGPGMVSVVGPMGLLVVLLVGGCAAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSISPKNFKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTAWTAFNLLNGKPSVAPKPDADGFIMVYLPDGQSPVPVQSYFIVMVPLRKSRGGQFLTPLGSPEDMDLEELIQDISRLQRRSLRHSRQLEVPRPYIAARFSVLPPTFHPGDQKQYGGFDNRGLEPGHRYVLFVLAVLQKSEPTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGMLSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYAT 50 2.1 5 3 3 2 2 0.878 0.876 0.907 2 2 2 - - - 0.887 0.017349352 tr|A0A0A0MR60|A0A0A0MR60_HUMAN 100 0 gi|104487611|ref|NP_570925.2| receptor-type tyrosine-protein phosphatase S isoform 4 precursor [Homo sapiens] 95.64 0 sp|Q13332|PTPRS_HUMAN Receptor-type tyrosine-protein phosphatase S OS=Homo sapiens GN=PTPRS PE=1 SV=3 99.93 0 F5H2T4 F5H2T4_HUMAN Receptor-type tyrosine-protein phosphatase S OS=Homo sapiens GN=PTPRS PE=4 SV=1 SPAC11E3.09 147 2.00E-34 COG5599 Protein tyrosine phosphatase T Signal transduction mechanisms ; K06778|1|0.0|2749|mgp:100551029|protein tyrosine phosphatase, receptor type, S [EC:3.1.3.48]!K06777|3|0.0|2321|hsa:5789|protein tyrosine phosphatase, receptor type, D [EC:3.1.3.48] GO:0021987//cerebral cortex development;GO:0021510//spinal cord development;GO:0007155//cell adhesion;GO:0021549//cerebellum development;GO:0021766//hippocampus development;GO:0022038//corpus callosum development;GO:0035335//peptidyl-tyrosine dephosphorylation GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding GO:0005887//integral to plasma membrane 386 tr|M0R009|M0R009_HUMAN Alpha-1B-glycoprotein (Fragment) OS=Homo sapiens GN=A1BG PE=4 SV=3 37179 LTCQAHLETPDFQLFKNGVAQEPVHLDSPAIKHQFLLTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPVHQPGNYSCSYRTDGEGALSEPSATVTIEELGPGPGSWPHGCLGLMVAKEFGQRMPKEWKAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRIFFHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEPESGRALRL 43 2.3 2 3 3 1 1 0.711 0.73 0.652 3 3 3 * * * 0.697666667 0.040673497 tr|M0R009|M0R009_HUMAN 99.16 2.00E-62 gi|193786308|dbj|BAG51591.1| unnamed protein product [Homo sapiens] 90.52 6.00E-156 sp|P04217|A1BG_HUMAN Alpha-1B-glycoprotein OS=Homo sapiens GN=A1BG PE=1 SV=4 99.16 7.00E-62 B3KP79 B3KP79_HUMAN cDNA FLJ31323 fis, clone LIVER2000037, highly similar to Alpha-1B-glycoprotein OS=Homo sapiens PE=2 SV=1 - - - - - - - K06512|1|7e-12|71.6|ptr:450148|leukocyte immunoglobulin-like receptor - - GO:0005576//extracellular region 387 sp|Q6UVY6|MOXD1_HUMAN DBH-like monooxygenase protein 1 OS=Homo sapiens GN=MOXD1 PE=2 SV=1 79950 MCCWPLLLLWGLLPGTAAGGSGRTYPHRTLLDSEGKYWLGWSQRGSQIAFRLQVRTAGYVGFGFSPTGAMASADIVVGGVAHGRPYLQDYFTNANRELKKDAQQDYHLEYAMENSTHTIIEFTRELHTCDINDKSITDSTVRVIWAYHHEDAGEAGPKYHDSNRGTKSLRLLNPEKTSVLSTALPYFDLVNQDVPIPNKDTTYWCQMFKIPVFQEKHHVIKVEPVIQRGHESLVHHILLYQCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSLFHTIPPGMPEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAGRGIRLRHFRKGKEMKLLAYDDDFDFNFQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRSEMCLSYLLYYPRINLTRCASIPDIMEQLQFIGVKEIYRPVTTWPFIIKSPKQYKNLSFMDAMNKFKWTKKEGLSFNKLVLSLPVNVRCSKTDNAEWSIQGMTALPPDIERPYKAEPLVCGTSSSSSLHRDFSINLLVCLLLLSCTLSTKSL 43 3.9 - 2 2 2 2 0.784 1.096 0.451 2 2 2 - - - 0.777 0.322556972 sp|Q6UVY6|MOXD1_HUMAN 100 0 gi|118421087|ref|NP_056344.2| DBH-like monooxygenase protein 1 precursor [Homo sapiens] >gi|74749373|sp|Q6UVY6.1|MOXD1_HUMAN RecName: Full=DBH-like monooxygenase protein 1; AltName: Full=Monooxygenase X; Flags: Precursor >gi|37183305|gb|AAQ89452.1| dopamine-oxygenase [Homo sapiens] >gi|119568418|gb|EAW48033.1| monooxygenase, DBH-like 1, isoform CRA_b [Homo sapiens] 100 0 sp|Q6UVY6|MOXD1_HUMAN DBH-like monooxygenase protein 1 OS=Homo sapiens GN=MOXD1 PE=2 SV=1 99.66 0 H2QTR2 H2QTR2_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000079931 PE=4 SV=1 - - - - - - - K15266|1|4e-96|352|bfo:BRAFLDRAFT_125270|dimethyladenosine transferase 1, mitochondrial!K00503|3|6e-77|288|xtr:100492247|dopamine beta-monooxygenase [EC:1.14.17.1] GO:0006584//catecholamine metabolic process;GO:0055114//oxidation-reduction process GO:0005507//copper ion binding;GO:0004500//dopamine beta-monooxygenase activity GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral to membrane 388 tr|A4D2D2|A4D2D2_HUMAN Procollagen C-endopeptidase enhancer OS=Homo sapiens GN=PCOLCE PE=4 SV=1 55476 MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGSEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTEPKVKLPPKSQPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPGEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQCPPMKKGVSYLLMGQVEENRGPVLPPESFVVLHRPNQDQILTNLSKRKCPSQPVRAAASQD 1276 38.5 1 66 66 12 12 1.668 1.669 2.011 47 47 47 * * * 1.782666667 0.197743099 tr|A4D2D2|A4D2D2_HUMAN 100 0 gi|51094573|gb|EAL23825.1| procollagen C-endopeptidase enhancer [Homo sapiens] 99.78 0 sp|Q15113|PCOC1_HUMAN Procollagen C-endopeptidase enhancer 1 OS=Homo sapiens GN=PCOLCE PE=1 SV=2 100 0 A4D2D2 A4D2D2_HUMAN Procollagen C-endopeptidase enhancer OS=Homo sapiens GN=PCOLCE PE=4 SV=1 - - - - - - - K05502|1|5e-46|185|xla:397872|bone morphogenetic protein 1 [EC:3.4.24.19] GO:0010952//positive regulation of peptidase activity;GO:0007275//multicellular organismal development;GO:0006508//proteolysis GO:0008201//heparin binding;GO:0005518//collagen binding;GO:0016504//peptidase activator activity GO:0005615//extracellular space;GO:0031012//extracellular matrix 389 tr|B2R983|B2R983_HUMAN cDNA, FLJ94267, highly similar to Homo sapiens glutathione S-transferase omega 1 (GSTO1), mRNA OS=Homo sapiens PE=2 SV=1 35107 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGSSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL 278 23.7 1 23 23 6 6 0.56 0.781 0.5 6 6 6 * - * 0.613666667 0.147987612 tr|B2R983|B2R983_HUMAN 100 4.00E-139 gi|189053923|dbj|BAG36430.1| unnamed protein product [Homo sapiens] 99.59 1.00E-139 sp|P78417|GSTO1_HUMAN Glutathione S-transferase omega-1 OS=Homo sapiens GN=GSTO1 PE=1 SV=2 100 1.00E-138 B2R983 B2R983_HUMAN cDNA, FLJ94267, highly similar to Homo sapiens glutathione S-transferase omega 1 (GSTO1), mRNA OS=Homo sapiens PE=2 SV=1 NMB1953 85.9 5.00E-17 COG0625 Glutathione S-transferase O Posttranslational modification, protein turnover, chaperones ; K00799|1|3e-138|491|pon:100447725|glutathione S-transferase [EC:2.5.1.18] GO:0042178//xenobiotic catabolic process;GO:0019853//L-ascorbic acid biosynthetic process;GO:0071243//cellular response to arsenic-containing substance GO:0004364//glutathione transferase activity;GO:0050610//methylarsonate reductase activity;GO:0045174//glutathione dehydrogenase (ascorbate) activity GO:0005829//cytosol 390 tr|I3L0A0|I3L0A0_HUMAN HCG2044781 OS=Homo sapiens GN=TMEM189-UBE2V1 PE=4 SV=1 47315 MAGAENWPGQQLELDEDEASCCRWGAQHAGARELAALYSPGKRLQEWCSVILCFSLIAHNLVHLLLLARWEDTPLVILGVVAGALIADFLSGLVHWGADTWGSVELPIVGKAFIRPFREHHIDPTAITRHDFIETNGDNCLVTLLPLLNMAYKFRTHSPEALEQLYPWECFVFCLIIFGTFTNQIHKWSHTYFGLPRWVTLLQDWHVILPRKHHRIHHVSPHETYFCITTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN 85 10 1 8 8 4 4 0.631 0.652 0.619 2 2 2 * - - 0.634 0.016703293 tr|I3L0A0|I3L0A0_HUMAN 100 5.00E-62 gi|381289239|gb|AFG21860.1| UBE2V1, partial [Capra hircus] 99.29 9.00E-72 sp|Q3SZ52|UB2V1_BOVIN Ubiquitin-conjugating enzyme E2 variant 1 OS=Bos taurus GN=UBE2V1 PE=2 SV=1 100 2.00E-61 H9TKZ2 H9TKZ2_CAPHI UBE2V1 (Fragment) OS=Capra hircus GN=UBE2V1 PE=2 SV=1 - - - - - - - K10704|1|0.0|717|hsa:387522|ubiquitin-conjugating enzyme E2 variant - - 391 tr|A8K8U1|A8K8U1_HUMAN cDNA FLJ77762, highly similar to Homo sapiens cullin-associated and neddylation-dissociated 1 (CAND1), mRNA OS=Homo sapiens PE=2 SV=1 161974 MASASYHISNLLEKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDKNGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPASSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSMSTTRTYIQCIAAISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPKEVYPHVSTIINICLKYLTYDPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCLDAVVSTRHEMLPEFYKTVSPALISRFKEREENVKADVFHAYLSLLKQTRPVQSWLCDPDAMEQGETPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGGPFYKITSEALLVTQQLVKVIRPLDQPSSFDATPYIKDLFTCTIKRLKAADIDQEVKERAISCMGQIICNLGDNLGSDLPNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVLGEGVPILASFLRKNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHVSQMAISFLTTLAKVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLRMLTGPVYSQSTALTHKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNSRSTDSIRLLALLSLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEITSQPKRQYLLLHSLKEIISSASVVGLKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTLIDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIGDFLKTLEDPDLNVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVEMGPFKHTVDDGLDIRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFLMLVRLSTLCPSAVLQRLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLTIPEAEKSPLMSEFQSQISSNPELAAIFESIQKDSSSTNLESMDTS 146 8.8 1 11 11 8 8 1.191 1.427 1.339 7 6 5 - * - 1.319 0.119264412 tr|A8K8U1|A8K8U1_HUMAN 100 4.00E-132 gi|444726491|gb|ELW67022.1| Cullin-associated NEDD8-dissociated protein 1 [Tupaia chinensis] 99.92 0 sp|A7MBJ5|CAND1_BOVIN Cullin-associated NEDD8-dissociated protein 1 OS=Bos taurus GN=CAND1 PE=2 SV=1 100 0 Q4R3A9 Q4R3A9_MACFA Testis cDNA clone: QtsA-18262, similar to human TBP-interacting protein (TIP120A), OS=Macaca fascicularis PE=2 SV=1 - - - - - - - - GO:0045899//positive regulation of RNA polymerase II transcriptional preinitiation complex assembly;GO:0016567//protein ubiquitination;GO:0043086//negative regulation of catalytic activity;GO:0030154//cell differentiation GO:0017025//TBP-class protein binding GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus 392 tr|G3V1S6|G3V1S6_HUMAN Polypeptide N-acetylgalactosaminyltransferase OS=Homo sapiens GN=GALNT2 PE=3 SV=1 71783 MADREDWNEIDPIKKKDLHHSNGEEKAQSMETLPPGKVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPDTRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQQWKFTLNLQQ 93 3.4 2 7 7 2 2 1.144 1.043 0.763 3 3 3 - - - 0.983333333 0.197383721 tr|G3V1S6|G3V1S6_HUMAN 100 0 gi|88192992|pdb|2FFU|A Chain A, Crystal Structure Of Human Ppgalnact-2 Complexed With Udp And Ea2 >gi|88192994|pdb|2FFV|A Chain A, Human Ppgalnact-2 Complexed With Manganese And Udp >gi|88192995|pdb|2FFV|B Chain B, Human Ppgalnact-2 Complexed With Manganese And Udp 99.81 0 sp|Q10471|GALT2_HUMAN Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens GN=GALNT2 PE=1 SV=1 100 0 G3V1S6 G3V1S6_HUMAN Polypeptide N-acetylgalactosaminyltransferase 2 soluble form OS=Homo sapiens GN=GALNT2 PE=3 SV=1 - - - - - - - K00710|1|0.0|1110|hsa:2590|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0018242//protein O-linked glycosylation via serine;GO:0018243//protein O-linked glycosylation via threonine;GO:0002378//immunoglobulin biosynthetic process;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing GO:0030145//manganese ion binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0030246//carbohydrate binding GO:0032580//Golgi cisterna membrane;GO:0030173//integral to Golgi membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005576//extracellular region 393 tr|Q96PQ9|Q96PQ9_HUMAN Lysyl oxidase OS=Homo sapiens GN=LOX PE=4 SV=1 49754 MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPPREPPAAPGAWRQQIQWENNGQVFSLLSLGSQYQPQRRRDPGAAVPGAANASAQQPRTPILLIRDNRTAAARTRTAGSSGVTAGRPRPTARHWFQAGYSTSRAREPGASRAENQTAPGEVPALSNLRPPSRVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY 82 4.1 1 6 6 2 2 1.768 1.614 1.501 3 3 3 * - - 1.627666667 0.13402363 tr|Q96PQ9|Q96PQ9_HUMAN 100 3.00E-66 gi|164691163|dbj|BAF98764.1| unnamed protein product [Homo sapiens] 99.76 0 sp|P28300|LYOX_HUMAN Protein-lysine 6-oxidase OS=Homo sapiens GN=LOX PE=1 SV=2 100 9.00E-66 F7IJL3 F7IJL3_CALJA Uncharacterized protein OS=Callithrix jacchus GN=LOC100407991 PE=4 SV=1 - - - - - - - K00277|1|0.0|665|ptr:471614|protein-lysine 6-oxidase [EC:1.4.3.13] GO:0042060//wound healing;GO:0030324//lung development;GO:0055114//oxidation-reduction process;GO:0048545//response to steroid hormone stimulus;GO:0048251//elastic fiber assembly;GO:0006464//cellular protein modification process;GO:0030199//collagen fibril organization;GO:0042493//response to drug;GO:0001568//blood vessel development GO:0005507//copper ion binding;GO:0004720//protein-lysine 6-oxidase activity;GO:0005515//protein binding GO:0005581//collagen;GO:0005615//extracellular space;GO:0005634//nucleus 394 sp|P23142|FBLN1_HUMAN Fibulin-1 OS=Homo sapiens GN=FBLN1 PE=1 SV=4 86744 MERAAPSRRVPLPLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVFDPVHTISHTVISLPTFREFTRPEEIIFLRAITPPHPASQANIIFDITEGNLRDSFDIIKRYMDGMTVGVVRQVRPIVGPFHAVLKLEMNYVVGGVVSHRNVVNVHIFVSEYWF 2928 27.3 - 129 65 14 5 1.778 2.26 1.894 44 45 43 * * - 1.977333333 0.251573714 sp|P23142|FBLN1_HUMAN 100 0 gi|215274249|sp|P23142.4|FBLN1_HUMAN RecName: Full=Fibulin-1; Short=FIBL-1; Flags: Precursor 100 0 sp|P23142|FBLN1_HUMAN Fibulin-1 OS=Homo sapiens GN=FBLN1 PE=1 SV=4 100 7.00E-80 B1AHM9 B1AHM9_HUMAN Fibulin 1 (Fragment) OS=Homo sapiens GN=FBLN1 PE=4 SV=1 - - - - - - - K08023|1|8e-54|212|mmu:268977|latent transforming growth factor beta binding protein GO:0010952//positive regulation of peptidase activity;GO:0019048//virus-host interaction;GO:0030198//extracellular matrix organization GO:0016504//peptidase activator activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005509//calcium ion binding GO:0005615//extracellular space;GO:0005604//basement membrane 395 tr|A0A024R8V7|A0A024R8V7_HUMAN TIMP metallopeptidase inhibitor 2, isoform CRA_b OS=Homo sapiens GN=TIMP2 PE=4 SV=1 26475 MPVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP 1258 55.3 1 56 56 9 9 1.386 1.279 1.194 46 46 45 - - - 1.286333333 0.09620984 tr|A0A024R8V7|A0A024R8V7_HUMAN 100 7.00E-103 gi|426346527|ref|XP_004040928.1| PREDICTED: uncharacterized protein LOC101152140 [Gorilla gorilla gorilla] 100 7.00E-103 sp|P16035|TIMP2_HUMAN Metalloproteinase inhibitor 2 OS=Homo sapiens GN=TIMP2 PE=1 SV=2 100 1.00E-100 G7PT18 G7PT18_MACFA Putative uncharacterized protein (Fragment) OS=Macaca fascicularis GN=EGM_08230 PE=4 SV=1 - - - - - - - - GO:0022617//extracellular matrix disassembly;GO:0010951//negative regulation of endopeptidase activity;GO:0045930//negative regulation of mitotic cell cycle;GO:0045762//positive regulation of adenylate cyclase activity;GO:0032487//regulation of Rap protein signal transduction;GO:0046580//negative regulation of Ras protein signal transduction;GO:0071310//cellular response to organic substance;GO:0008285//negative regulation of cell proliferation;GO:0045861//negative regulation of proteolysis;GO:0045666//positive regulation of neuron differentiation;GO:0043410//positive regulation of MAPK cascade GO:0005178//integrin binding;GO:0008047//enzyme activator activity;GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity;GO:0008191//metalloendopeptidase inhibitor activity GO:0005604//basement membrane;GO:0030426//growth cone;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0043025//neuronal cell body;GO:0005634//nucleus 396 sp|Q12841|FSTL1_HUMAN Follistatin-related protein 1 OS=Homo sapiens GN=FSTL1 PE=1 SV=1 44317 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNETAINITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQETAEKTKRVSTKEI 1257 35.1 - 96 89 10 9 0.734 0.583 0.637 50 50 51 * * - 0.651333333 0.076513615 sp|Q12841|FSTL1_HUMAN 100 1.00E-159 gi|355746446|gb|EHH51060.1| hypothetical protein EGM_10384, partial [Macaca fascicularis] 100 3.00E-160 sp|Q12841|FSTL1_HUMAN Follistatin-related protein 1 OS=Homo sapiens GN=FSTL1 PE=1 SV=1 100 3.00E-67 Q9BZQ0 Q9BZQ0_HUMAN Follistatin-related protein (Fragment) OS=Homo sapiens PE=2 SV=1 - - - - - - - K06254|1|7e-11|68.2|tca:100141763|agrin GO:0030509//BMP signaling pathway GO:0008201//heparin binding;GO:0005509//calcium ion binding GO:0005615//extracellular space 397 sp|P25391|LAMA1_HUMAN Laminin subunit alpha-1 OS=Homo sapiens GN=LAMA1 PE=1 SV=2 389834 MRGGVLLVLLLCVAAQCRQRGLFPAILNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLDGTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDLSPKLLEFTSARYIRLRLQRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMSGWLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPENFQDFHSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYFNSVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGRKAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETDCVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALELSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSADRDCIRAYQPQISSTNYNTLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDVNNSTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGKSIGLWNYIEREGKCRGCFGSSQNEDPSFHFDGSGYSVVEKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKNLEISRSTFDLLRNSYGVRKGCLLEPIRSVSFLKGGYIELPPKSLSPESEWLVTFATTNSSGIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSISLVRNRRIITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKNLIFNLELLDFNSAVGHEQVDLDTCWLSERPKLAPDAEDSKLLPEPRAFPEQCVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDKDSPVSAFTVNRCYAVAQEGTYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIKSPQVQSFDFSRAFELHGVFLHSCPGTES 70 1.1 - 4 4 3 3 1.907 1.518 1.537 2 2 2 - - - 1.654 0.219310282 sp|P25391|LAMA1_HUMAN 100 0 gi|38788416|ref|NP_005550.2| laminin subunit alpha-1 precursor [Homo sapiens] >gi|281185471|sp|P25391.2|LAMA1_HUMAN RecName: Full=Laminin subunit alpha-1; AltName: Full=Laminin A chain; AltName: Full=Laminin-1 subunit alpha; AltName: Full=Laminin-3 subunit alpha; AltName: Full=S-laminin subunit alpha; Short=S-LAM alpha; Flags: Precursor 100 0 sp|P25391|LAMA1_HUMAN Laminin subunit alpha-1 OS=Homo sapiens GN=LAMA1 PE=1 SV=2 100 0 Q7Z5W6 Q7Z5W6_HUMAN LAMA1 protein (Fragment) OS=Homo sapiens GN=LAMA1 PE=2 SV=1 - - - - - - - K05637|1|0.0|6301|hsa:284217|laminin, alpha 1/2 GO:0007411//axon guidance;GO:0030155//regulation of cell adhesion;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060445//branching involved in salivary gland morphogenesis;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0045995//regulation of embryonic development;GO:0002011//morphogenesis of an epithelial sheet;GO:0030334//regulation of cell migration;GO:0061304//retinal blood vessel morphogenesis;GO:0007166//cell surface receptor signaling pathway GO:0043208//glycosphingolipid binding;GO:0005102//receptor binding;GO:0005201//extracellular matrix structural constituent GO:0005608//laminin-3 complex;GO:0005606//laminin-1 complex;GO:0005615//extracellular space;GO:0005911//cell-cell junction 398 sp|O43707|ACTN4_HUMAN Alpha-actinin-4 OS=Homo sapiens GN=ACTN4 PE=1 SV=2 123193 MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDALGSLTHSRREALEKTEKQLEAIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANVVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLDLLEQQHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQGEAEFNRIMSLVDPNHSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAVPGALDYKSFSTALYGESDL 4367 43.2 - 208 110 33 20 0.658 0.577 0.523 87 86 85 - * * 0.586 0.06794851 sp|O43707|ACTN4_HUMAN 100 0 gi|2804273|dbj|BAA24447.1| alpha actinin 4 [Homo sapiens] 100 0 sp|O43707|ACTN4_HUMAN Alpha-actinin-4 OS=Homo sapiens GN=ACTN4 PE=1 SV=2 100 0 H2QG89 H2QG89_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000130402 PE=4 SV=1 SPAC15A10.08 259 1.00E-68 COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) Z Cytoskeleton ; K05699|1|0.0|1859|ptr:456010|actinin alpha GO:0030168//platelet activation;GO:0042981//regulation of apoptotic process;GO:0051017//actin filament bundle assembly;GO:0051272//positive regulation of cellular component movement;GO:0048549//positive regulation of pinocytosis;GO:0015031//protein transport;GO:0032417//positive regulation of sodium:hydrogen antiporter activity;GO:0001666//response to hypoxia;GO:0002576//platelet degranulation;GO:0051271//negative regulation of cellular component movement GO:0005178//integrin binding;GO:0047485//protein N-terminus binding;GO:0005509//calcium ion binding;GO:0051015//actin filament binding;GO:0001882//nucleoside binding;GO:0042803//protein homodimerization activity GO:0030863//cortical cytoskeleton;GO:0031143//pseudopodium;GO:0031093//platelet alpha granule lumen;GO:0005576//extracellular region;GO:0005829//cytosol;GO:0043234//protein complex;GO:0001725//stress fiber;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0030529//ribonucleoprotein complex 399 tr|C9JF17|C9JF17_HUMAN Apolipoprotein D (Fragment) OS=Homo sapiens GN=APOD PE=4 SV=1 28800 MFKQLSCISLPSSCDYSSRSLLQPPSPKMVMLLLLLSALAGLFGAAEGQAFHLGKCPNPPVQENFDVNKYLGRWYEIEKIPTTFENGRCIQANYSLMENGKIKVLNQELRADGTVNQIEGEATPVNLTEPAKLEVKFSWFMPSAPYWILATDYENYALVYSCTCIIQLFHVDFAWILARNPNLPPETVDSLKNILTSNNIDVKKMTVTDQVNCPK 125 20.5 1 11 11 4 4 1.227 4.864 3.442 5 6 5 - - * 3.177666667 1.832851967 tr|C9JF17|C9JF17_HUMAN 100 2.00E-95 gi|619383|gb|AAB32200.1| apolipoprotein D, apoD [human, plasma, Peptide, 246 aa] 100 1.00E-95 sp|P05090|APOD_HUMAN Apolipoprotein D OS=Homo sapiens GN=APOD PE=1 SV=1 100 2.00E-46 B4DGC3 B4DGC3_HUMAN cDNA FLJ57921, highly similar to Apolipoprotein D OS=Homo sapiens PE=2 SV=1 PA5107 77 2.00E-14 COG3040 Bacterial lipocalin M Cell wall/membrane/envelope biogenesis ; K03098|1|6e-08|57.8|hmg:100208577|outer membrane lipoprotein Blc GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0006006//glucose metabolic process;GO:0014012//peripheral nervous system axon regeneration;GO:0006869//lipid transport;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0007420//brain development;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:2000405//negative regulation of T cell migration;GO:0051895//negative regulation of focal adhesion assembly;GO:0007568//aging;GO:0042246//tissue regeneration;GO:0000302//response to reactive oxygen species;GO:0042308//negative regulation of protein import into nucleus;GO:0001525//angiogenesis;GO:0060588//negative regulation of lipoprotein lipid oxidation;GO:0042493//response to drug;GO:2000098//negative regulation of smooth muscle cell-matrix adhesion;GO:0071638//negative regulation of monocyte chemotactic protein-1 production GO:0036094//small molecule binding;GO:0005319//lipid transporter activity;GO:0015485//cholesterol binding;GO:0005515//protein binding GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0022626//cytosolic ribosome;GO:0048471//perinuclear region of cytoplasm;GO:0030425//dendrite;GO:0043025//neuronal cell body 400 sp|Q6UWH4|F198B_HUMAN Protein FAM198B OS=Homo sapiens GN=FAM198B PE=2 SV=1 67688 MTCPDKPGQLINWFICSLCVPRVRKLWSSRRPRTRRNLLLGTACAIYLGFLVSQVGRASLQHGQAAEKGPHRSRDTAEPSFPEIPLDGTLAPPESQGNGSTLQPNVVYITLRSKRSKPANIRGTVKPKRRKKHAVASAAPGQEALVGPSLQPQEAAREADAVAPGYAQGANLVKIGERPWRLVRGPGVRAGGPDFLQPSSRESNIRIYSESAPSWLSKDDIRRMRLLADSAVAGLRPVSSRSGARLLVLEGGAPGAVLRCGPSPCGLLKQPLDMSEVFAFHLDRILGLNRTLPSVSRKAEFIQDGRPCPIILWDASLSSASNDTHSSVKLTWGTYQQLLKQKCWQNGRVPKPESGCTEIHHHEWSKMALFDFLLQIYNRLDTNCCGFRPRKEDACVQNGLRPKCDDQGSAALAHIIQRKHDPRHLVFIDNKGFFDRSEDNLNFKLLEGIKEFPASAVSVLKSQHLRQKLLQSLFLDKVYWESQGGRQGIEKLIDVIEHRAKILITYINAHGVKVLPMNE 130 7.7 - 5 5 3 3 1.001 1.164 1.091 4 4 3 - - - 1.085333333 0.081647617 sp|Q6UWH4|F198B_HUMAN 100 0 gi|119625269|gb|EAX04864.1| chromosome 4 open reading frame 18, isoform CRA_b [Homo sapiens] 100 0 sp|Q6UWH4|F198B_HUMAN Protein FAM198B OS=Homo sapiens GN=FAM198B PE=2 SV=1 100 1.00E-173 B4E252 B4E252_HUMAN cDNA FLJ61056 OS=Homo sapiens PE=2 SV=1 - - - - - - - - - - GO:0000139//Golgi membrane;GO:0016021//integral to membrane 401 sp|Q5VTE0|EF1A3_HUMAN Putative elongation factor 1-alpha-like 3 OS=Homo sapiens GN=EEF1A1P5 PE=5 SV=1 65401 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFKVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHMAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK 499 16.5 11 33 33 6 6 0.569 0.397 0.515 22 22 21 - * * 0.493666667 0.087962113 sp|Q5VTE0|EF1A3_HUMAN 100 0 gi|74746925|sp|Q5VTE0.1|EF1A3_HUMAN RecName: Full=Putative elongation factor 1-alpha-like 3; Short=EF-1-alpha-like 3; AltName: Full=Eukaryotic elongation factor 1 A-like 3; Short=eEF1A-like 3; AltName: Full=Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5 100 0 sp|Q5VTE0|EF1A3_HUMAN Putative elongation factor 1-alpha-like 3 OS=Homo sapiens GN=EEF1A1P5 PE=5 SV=1 99.57 0 Q0PY11 Q0PY11_PIG Elongation factor 1-alpha OS=Sus scrofa GN=EEF1A PE=2 SV=1 SPCC794.09c 774 0 COG5256 Translation elongation factor EF-1alpha (GTPase) J Translation, ribosomal structure and biogenesis ; K03231|1|0.0|900|ssc:574059|elongation factor 1-alpha GO:0006355//regulation of transcription, DNA-dependent;GO:0006414//translational elongation;GO:0006184//GTP catabolic process GO:0019901//protein kinase binding;GO:0003746//translation elongation factor activity;GO:0005525//GTP binding;GO:0003924//GTPase activity GO:0005829//cytosol;GO:0005853//eukaryotic translation elongation factor 1 complex;GO:0005634//nucleus 402 tr|Q6FHL9|Q6FHL9_HUMAN PEA15 protein OS=Homo sapiens GN=PEA15 PE=2 SV=1 19375 MVEYGTLLQDLTNNITLEDLEQLKSACKEDIPSEKSEEITTGSAWFSFLESHNKLDKDNLSYIEHIFEISRRPDLLTMVVDYRTRVLKISEEDELDTKLTRIPSAKKYKDIIRQPSEEEIIKLAPPPKKA 285 23.8 1 14 14 2 2 0.706 0.784 0.546 12 13 13 * * * 0.678666667 0.121331502 tr|Q6FHL9|Q6FHL9_HUMAN 100 2.00E-66 gi|332811039|ref|XP_003308618.1| PREDICTED: astrocytic phosphoprotein PEA-15, partial [Pan troglodytes] 99.23 1.00E-69 sp|Q9Z297|PEA15_CRIGR Astrocytic phosphoprotein PEA-15 OS=Cricetulus griseus GN=PEA15 PE=1 SV=1 100 3.00E-57 F7DQD4 F7DQD4_MACMU Uncharacterized protein (Fragment) OS=Macaca mulatta GN=Mmu.4628 PE=4 SV=1 - - - - - - - - GO:0035556//intracellular signal transduction;GO:0046325//negative regulation of glucose import;GO:0043278//response to morphine GO:0005080//protein kinase C binding GO:0005875//microtubule associated complex;GO:0005737//cytoplasm 403 tr|Q0D2M2|Q0D2M2_HUMAN HIST1H2BC protein OS=Homo sapiens GN=HIST1H2BC PE=2 SV=1 20214 MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSGGTKAVTKYTSSK 82 14.3 13 8 8 2 2 1.572 1.81 1.983 4 4 4 * * * 1.788333333 0.206354872 tr|Q0D2M2|Q0D2M2_HUMAN 100 7.00E-47 gi|114205460|gb|AAI05596.1| HIST1H2BC protein [Homo sapiens] 100 5.00E-12 sp|P02280|H2B_CRONI Histone H2B (Fragment) OS=Crocodylus niloticus PE=1 SV=2 100 3.00E-46 Q0D2M2 Q0D2M2_HUMAN HIST1H2BC protein OS=Homo sapiens GN=HIST1H2BC PE=2 SV=1 - - - - - - - K11252|1|7e-49|191|mcc:696872|histone H2B!K11253|2|3e-47|186|mcc:704845|histone H3 GO:0006334//nucleosome assembly GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity GO:0000786//nucleosome;GO:0005634//nucleus 404 tr|B4DDD8|B4DDD8_HUMAN Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens GN=HARS PE=1 SV=1 60612 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLCIC 131 14.5 1 10 10 6 6 0.924 0.629 0.97 3 3 3 - - - 0.841 0.18503243 tr|B4DDD8|B4DDD8_HUMAN 100 2.00E-179 gi|350539291|ref|NP_001233308.1| histidyl-tRNA synthetase, cytoplasmic-like [Pan troglodytes] >gi|343962243|dbj|BAK62709.1| histidyl-tRNA synthetase [Pan troglodytes] 100 2.00E-180 sp|P12081|SYHC_HUMAN Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens GN=HARS PE=1 SV=2 100 2.00E-178 B3KWE1 B3KWE1_HUMAN Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens GN=HARS PE=2 SV=1 SPBC2G2.12 313 3.00E-85 COG0124 Histidyl-tRNA synthetase J Translation, ribosomal structure and biogenesis ; K01892|1|2e-180|632|hsa:3035|histidyl-tRNA synthetase [EC:6.1.1.21] - - 405 tr|B3KRN4|B3KRN4_HUMAN cDNA FLJ34625 fis, clone KIDNE2015244, highly similar to Serine protease HTRA1 (EC 3.4.21.-) OS=Homo sapiens PE=2 SV=1 57113 MGWAARPRALAPAAPEALLHSPRRRSPALALSNTYANLCQQRAGVRLLRGVRRARGRRVRPAGGPVRRGAAVRGALRGASLGHGAAARAGRPLCVRQQLRAASRRSERLHRPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKAKELKDRHRDFPDVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKRESTLNMVVRRGNEDIMITVIPEEIDP 863 13.6 2 50 50 6 6 2.113 1.888 2.143 29 28 29 * * - 2.048 0.139373599 tr|B3KRN4|B3KRN4_HUMAN 100 5.00E-115 gi|387766125|pdb|3TJN|A Chain A, Htra1 Catalytic Domain, Apo Form >gi|387766126|pdb|3TJN|B Chain B, Htra1 Catalytic Domain, Apo Form >gi|387766127|pdb|3TJN|D Chain D, Htra1 Catalytic Domain, Apo Form 99.15 0 sp|Q92743|HTRA1_HUMAN Serine protease HTRA1 OS=Homo sapiens GN=HTRA1 PE=1 SV=1 100 0 H2Q2P9 H2Q2P9_PANTR Uncharacterized protein (Fragment) OS=Pan troglodytes GN=ENSG00000166033 PE=4 SV=1 sll1427 206 5.00E-53 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain O Posttranslational modification, protein turnover, chaperones ; K08784|1|0.0|706|hsa:5654|HtrA serine peptidase 1 [EC:3.4.21.-] GO:0030514//negative regulation of BMP signaling pathway;GO:0001558//regulation of cell growth;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0006508//proteolysis GO:0004252//serine-type endopeptidase activity;GO:0005520//insulin-like growth factor binding GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0005829//cytosol 406 sp|P62942|FKB1A_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP1A OS=Homo sapiens GN=FKBP1A PE=1 SV=2 14738 MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE 132 25 - 6 6 2 2 1.136 1.034 0.923 4 5 4 - - - 1.031 0.106531685 sp|P62942|FKB1A_HUMAN 100 4.00E-58 gi|238828310|pdb|3H9R|B Chain B, Crystal Structure Of The Kinase Domain Of Type I Activin Receptor (Acvr1) In Complex With Fkbp12 And Dorsomorphin >gi|296278515|pdb|3MDY|B Chain B, Crystal Structure Of The Cytoplasmic Domain Of The Bone Morp Protein Receptor Type-1b (Bmpr1b) In Complex With Fkbp12 An 193189 >gi|296278516|pdb|3MDY|D Chain D, Crystal Structure Of The Cytoplasmic Domain Of The Bone Morp Protein Receptor Type-1b (Bmpr1b) In Complex With Fkbp12 An 193189 100 5.00E-59 sp|P62943|FKB1A_RABIT Peptidyl-prolyl cis-trans isomerase FKBP1A OS=Oryctolagus cuniculus GN=FKBP1A PE=1 SV=2 100 1.00E-57 Q0VDC6 Q0VDC6_HUMAN Peptidyl-prolyl cis-trans isomerase OS=Homo sapiens GN=FKBP1A PE=2 SV=1 SPBC839.17c 135 1.00E-32 COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 O Posttranslational modification, protein turnover, chaperones ; K09568|1|2e-59|227|mcc:698165|FK506-binding protein 1 [EC:5.2.1.8] GO:0032925//regulation of activin receptor signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0042026//protein refolding;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB cascade;GO:0032092//positive regulation of protein binding;GO:0050776//regulation of immune response;GO:0006458//'de novo' protein folding;GO:0060347//heart trabecula formation;GO:0000413//protein peptidyl-prolyl isomerization;GO:0031398//positive regulation of protein ubiquitination;GO:0001933//negative regulation of protein phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0006936//muscle contraction;GO:0031000//response to caffeine;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0022417//protein maturation by protein folding;GO:0043206//extracellular fibril organization;GO:0042098//T cell proliferation;GO:0034205//beta-amyloid formation;GO:0032513//negative regulation of protein phosphatase type 2B activity;GO:0051209//release of sequestered calcium ion into cytosol;GO:0007183//SMAD protein complex assembly GO:0034713//type I transforming growth factor beta receptor binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005528//FK506 binding;GO:0005219//ryanodine-sensitive calcium-release channel activity;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0046332//SMAD binding;GO:0048185//activin binding GO:0014802//terminal cisterna;GO:0005829//cytosol;GO:0030424//axon;GO:0033017//sarcoplasmic reticulum membrane 407 sp|Q9Y680|FKBP7_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP7 OS=Homo sapiens GN=FKBP7 PE=1 SV=1 38242 MPKTMHFLFRFIVFFYLWGLFTAQRQKKEESTEEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYGSLEEVFLLQNILVSCHRTTLHVLKCMYLLVLNNNTCAEGKIPPDATLIFEIELYAVTKGPRSIETFKQIDMDNDRQLSKAEINLYLQREFEKDEKPRDKSYQDAVLEDIFKKNDHDGDGFISPKEYNVYQHDEL 127 8.9 - 3 3 2 2 --- 1.273 0.954 1 3 3 - - - 1.1135 0.225567063 sp|Q9Y680|FKBP7_HUMAN 100 8.00E-71 gi|119631432|gb|EAX11027.1| FK506 binding protein 7, isoform CRA_a [Homo sapiens] >gi|119631436|gb|EAX11031.1| FK506 binding protein 7, isoform CRA_a [Homo sapiens] 100 1.00E-153 sp|Q9Y680|FKBP7_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP7 OS=Homo sapiens GN=FKBP7 PE=1 SV=1 100 2.00E-33 H7BZJ4 H7BZJ4_HUMAN Peptidyl-prolyl cis-trans isomerase (Fragment) OS=Homo sapiens GN=FKBP7 PE=4 SV=1 YDR519w 72.4 8.00E-13 COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 O Posttranslational modification, protein turnover, chaperones ; K09573|1|4e-124|444|ptr:459778|FK506-binding protein 7 [EC:5.2.1.8] GO:0006457//protein folding;GO:0000413//protein peptidyl-prolyl isomerization GO:0005528//FK506 binding;GO:0005509//calcium ion binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane 408 sp|P08253|MMP2_HUMAN 72 kDa type IV collagenase OS=Homo sapiens GN=MMP2 PE=1 SV=2 >tr|A0A024R6R4|A0A024R6R4_HUMAN Matrix metallopeptidase 2 (Gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), isoform CRA_a OS=Homo sapiens GN=MMP2 PE=4 SV=1 88912 MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC 5262 51.2 - 327 327 26 26 2.048 1.71 2.14 206 207 207 * - - 1.966 0.22642438 sp|P08253|MMP2_HUMAN 100 2.00E-109 gi|157833752|pdb|1RTG|A Chain A, C-terminal Domain (haemopexin-like Domain) Of Human Matrix Metalloproteinase-2 100 0 sp|P08253|MMP2_HUMAN 72 kDa type IV collagenase OS=Homo sapiens GN=MMP2 PE=1 SV=2 100 5.00E-146 H9FL17 H9FL17_MACMU 72 kDa type IV collagenase isoform a preproprotein (Fragment) OS=Macaca mulatta GN=MMP2 PE=2 SV=1 - - - - - - - K01398|1|0.0|1249|mmu:17390|matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24] GO:0001525//angiogenesis;GO:0001957//intramembranous ossification;GO:0035094//response to nicotine;GO:0001541//ovarian follicle development;GO:0001542//ovulation from ovarian follicle;GO:0051602//response to electrical stimulus;GO:0060033//anatomical structure regression;GO:0022617//extracellular matrix disassembly;GO:0071347//cellular response to interleukin-1;GO:0042542//response to hydrogen peroxide;GO:0048771//tissue remodeling;GO:0014823//response to activity;GO:0009612//response to mechanical stimulus;GO:0032526//response to retinoic acid;GO:0007568//aging;GO:0060325//face morphogenesis;GO:0060740//prostate gland epithelium morphogenesis;GO:0007162//negative regulation of cell adhesion;GO:0055093//response to hyperoxia;GO:0001955//blood vessel maturation;GO:0045906//negative regulation of vasoconstriction;GO:0014012//peripheral nervous system axon regeneration;GO:0001666//response to hypoxia;GO:0043065//positive regulation of apoptotic process;GO:0060346//bone trabecula formation;GO:0030574//collagen catabolic process;GO:0007566//embryo implantation;GO:0042493//response to drug;GO:0009314//response to radiation;GO:0006508//proteolysis;GO:0016049//cell growth;GO:0071392//cellular response to estradiol stimulus;GO:0007567//parturition;GO:0016477//cell migration;GO:0071230//cellular response to amino acid stimulus GO:0008270//zinc ion binding;GO:0004252//serine-type endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0001968//fibronectin binding GO:0005615//extracellular space;GO:0005581//collagen;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0030017//sarcomere 409 sp|P13639|EF2_HUMAN Elongation factor 2 OS=Homo sapiens GN=EEF2 PE=1 SV=4 116324 MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQSKDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGPAERAKKVEDMMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGLVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL 641 18.4 - 38 38 16 16 0.988 0.641 0.837 22 22 22 - * * 0.822 0.173985632 sp|P13639|EF2_HUMAN 100 0 gi|4503483|ref|NP_001952.1| elongation factor 2 [Homo sapiens] >gi|119172|sp|P13639.4|EF2_HUMAN RecName: Full=Elongation factor 2; Short=EF-2 >gi|88909610|sp|Q5R8Z3.3|EF2_PONAB RecName: Full=Elongation factor 2; Short=EF-2 >gi|31106|emb|CAA35829.1| elongation factor 2 [Homo sapiens] >gi|31108|emb|CAA77750.1| human elongation factor 2 [Homo sapiens] >gi|60685056|gb|AAX34409.1| elongation factor 2 [Homo sapiens] >gi|116496673|gb|AAI26260.1| EEF2 protein [Homo sapiens] >gi|119589680|gb|EAW69274.1| eukaryotic translation elongation factor 2, isoform CRA_a [Homo sapiens] >gi|119589681|gb|EAW69275.1| eukaryotic translation elongation factor 2, isoform CRA_a [Homo sapiens] >gi|187953217|gb|AAI36314.1| EEF2 protein [Homo sapiens] 100 0 sp|P13639|EF2_HUMAN Elongation factor 2 OS=Homo sapiens GN=EEF2 PE=1 SV=4 100 0 G3RAS9 G3RAS9_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=EEF2 PE=4 SV=1 YOR133w 1186 0 COG0480 Translation elongation factors (GTPases) J Translation, ribosomal structure and biogenesis ; K03234|1|0.0|1725|hsa:1938|elongation factor 2 GO:0006414//translational elongation;GO:0006184//GTP catabolic process GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005525//GTP binding GO:0005829//cytosol;GO:0005844//polysome 410 tr|B2R9S4|B2R9S4_HUMAN cDNA, FLJ94534, highly similar to Homo sapiens capping protein (actin filament), gelsolin-like(CAPG), mRNA OS=Homo sapiens PE=2 SV=1 46364 MYTAIPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLNNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 122 13.2 2 7 7 3 3 1.118 1.266 1.961 3 5 4 - - - 1.448333333 0.450107024 tr|B2R9S4|B2R9S4_HUMAN 100 0 gi|189054101|dbj|BAG36621.1| unnamed protein product [Homo sapiens] 99.71 0 sp|P40121|CAPG_HUMAN Macrophage-capping protein OS=Homo sapiens GN=CAPG PE=1 SV=2 100 3.00E-147 E7ENU9 E7ENU9_HUMAN Macrophage-capping protein (Fragment) OS=Homo sapiens GN=CAPG PE=4 SV=1 - - - - - - - K10368|1|0.0|722|hsa:822|capping protein (actin filament), gelsolin-like GO:0007076//mitotic chromosome condensation;GO:0051301//cell division;GO:0030031//cell projection assembly;GO:0051016//barbed-end actin filament capping GO:0003779//actin binding GO:0031965//nuclear membrane;GO:0042470//melanosome;GO:0005576//extracellular region;GO:0005730//nucleolus;GO:0005813//centrosome;GO:0008290//F-actin capping protein complex;GO:0000796//condensin complex 411 sp|P23381|SYWC_HUMAN Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens GN=WARS PE=1 SV=2 >tr|A0A024R6K8|A0A024R6K8_HUMAN Tryptophanyl-tRNA synthetase, isoform CRA_a OS=Homo sapiens GN=WARS PE=3 SV=1 64425 MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ 364 13.4 - 14 14 5 5 1.176 1.263 1.084 11 10 7 - - - 1.174333333 0.089511638 sp|P23381|SYWC_HUMAN 100 1.00E-103 gi|194390522|dbj|BAG62020.1| unnamed protein product [Homo sapiens] 100 0 sp|P23381|SYWC_HUMAN Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens GN=WARS PE=1 SV=2 100 0 G2HE39 G2HE39_PANTR Tryptophanyl-tRNA synthetase OS=Pan troglodytes PE=2 SV=1 SPAC2F7.13c 478 8.00E-135 COG0180 Tryptophanyl-tRNA synthetase J Translation, ribosomal structure and biogenesis ; K01867|1|0.0|983|hsa:7453|tryptophanyl-tRNA synthetase [EC:6.1.1.2] GO:0008285//negative regulation of cell proliferation;GO:0006436//tryptophanyl-tRNA aminoacylation;GO:0045765//regulation of angiogenesis GO:0004830//tryptophan-tRNA ligase activity;GO:0005524//ATP binding;GO:0005515//protein binding GO:0005829//cytosol 412 tr|B4DEB9|B4DEB9_HUMAN cDNA FLJ61099, highly similar to ADP-ribosylation factor 1 OS=Homo sapiens PE=2 SV=1 23649 MGNIFANLFKGLFGKKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEARDELRDAVLLVFANKQDLPNAMNAAGITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK 193 20.2 3 11 9 3 2 0.94 0.915 1.084 5 5 6 - - - 0.979666667 0.091215861 tr|B4DEB9|B4DEB9_HUMAN 100 1.00E-97 gi|194374269|dbj|BAG57030.1| unnamed protein product [Homo sapiens] 93.96 9.00E-94 sp|Q4R5P2|ARF1_MACFA ADP-ribosylation factor 1 OS=Macaca fascicularis GN=ARF1 PE=2 SV=3 100 3.00E-97 B4DEB9 B4DEB9_HUMAN cDNA FLJ61099, highly similar to ADP-ribosylation factor 1 OS=Homo sapiens PE=2 SV=1 YDL137w 276 9.00E-75 COG1100 GTPase SAR1 and related small G proteins R General function prediction only ; K07937|1|9e-94|342|acs:100552859|ADP-ribosylation factor 1 GO:0016032//viral reproduction;GO:0015031//protein transport;GO:0006878//cellular copper ion homeostasis;GO:0006184//GTP catabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050690//regulation of defense response to virus by virus;GO:0007264//small GTPase mediated signal transduction;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0048205//COPI coating of Golgi vesicle GO:0005057//receptor signaling protein activity;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0005886//plasma membrane;GO:0030017//sarcomere 413 sp|P35998|PRS7_HUMAN 26S protease regulatory subunit 7 OS=Homo sapiens GN=PSMC2 PE=1 SV=3 59041 MPDYLGADQRKTKEDEKDDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN 75 14.5 - 8 8 5 5 1.032 0.567 0.699 3 3 3 - - - 0.766 0.239630966 sp|P35998|PRS7_HUMAN 100 0 gi|354480225|ref|XP_003502308.1| PREDICTED: 26S protease regulatory subunit 7-like [Cricetulus griseus] 100 0 sp|Q5E9F9|PRS7_BOVIN 26S protease regulatory subunit 7 OS=Bos taurus GN=PSMC2 PE=2 SV=3 100 0 Q75L23 Q75L23_HUMAN Putative uncharacterized protein PSMC2 (Fragment) OS=Homo sapiens GN=PSMC2 PE=2 SV=1 SPBC16C6.07c 670 0 COG1222 ATP-dependent 26S proteasome regulatory subunit O Posttranslational modification, protein turnover, chaperones ; K03061|1|0.0|827|cfa:475896|26S proteasome regulatory subunit T1 GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0019048//virus-host interaction;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006200//ATP catabolic process;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0017025//TBP-class protein binding;GO:0008233//peptidase activity;GO:0016887//ATPase activity;GO:0005524//ATP binding GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0000502//proteasome complex;GO:0005739//mitochondrion 414 tr|A0A087WV85|A0A087WV85_HUMAN Diphosphomevalonate decarboxylase OS=Homo sapiens GN=MVD PE=1 SV=1 16060 MGEQADGKDSIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPAHGGDGPLHPGARLPQLRPADHEGQQPVPRHLPRHLPPSLTSMPSPGASSTWCTASTPTTGTPRWRTPLTRAPMP 55 7.2 3 2 2 1 1 --- 0.782 --- 1 2 1 - - - 0.782 - tr|A0A087WV85|A0A087WV85_HUMAN 100 1.00E-28 gi|426383200|ref|XP_004058175.1| PREDICTED: diphosphomevalonate decarboxylase [Gorilla gorilla gorilla] 100 1.00E-29 sp|P53602|MVD1_HUMAN Diphosphomevalonate decarboxylase OS=Homo sapiens GN=MVD PE=1 SV=1 100 6.00E-10 F7H818 F7H818_CALJA Uncharacterized protein (Fragment) OS=Callithrix jacchus GN=MVD PE=4 SV=1 SPAC24C9.03 65.9 2.00E-11 COG3407 Mevalonate pyrophosphate decarboxylase I Lipid transport and metabolism ; K01597|1|1e-29|127|hsa:4597|diphosphomevalonate decarboxylase [EC:4.1.1.33] GO:0019287//isopentenyl diphosphate biosynthetic process, mevalonate pathway;GO:0042493//response to drug;GO:0008284//positive regulation of cell proliferation;GO:0006695//cholesterol biosynthetic process GO:0004163//diphosphomevalonate decarboxylase activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0042803//protein homodimerization activity;GO:0030544//Hsp70 protein binding GO:0005829//cytosol;GO:0005777//peroxisome 415 sp|Q96RW7|HMCN1_HUMAN Hemicentin-1 OS=Homo sapiens GN=HMCN1 PE=1 SV=2 703271 MISWEVVHTVFLFALLYSSLAQDASPQSEIRAEEIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLFNFALVPFHDPEIGPVTITTDPKKFQYELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRTHIGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLEQAVNTWRIPFDPSLKEVTVSLSGPSPMIEIRNPLGKLIKKGFGLHELLNIHNSAKVVNVKEPEAGMWTVKTSSSGRHSVRITGLSTIDFRAGFSRKPTLDFKKTVSRPVQGIPTYVLLNTSGISTPARIDLLELLSISGSSLKTIPVKYYPHRKPYGIWNISDFVPPNEAFFLKVTGYDKDDYLFQRVSSVSFSSIVPDAPKVTMPEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVIGNINDVEFGIAFLNATITDSPNSDTRIIRAKITNVPRSLGSAMRKIVSILNPIYWTTAKEIGEAVNGFTLTNAVFKRETQVEFATGEILQMSHIARGLDSDGSLLLDIVVSGYVLQLQSPAEVTVKDYTEDYIQTGPGQLYAYSTRLFTIDGISIPYTWNHTVFYDQAQGRMPFLVETLHASSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLECALSPYALEYKLVSLPFGIATNQDLIRLVAYTQDGVMHPRTTFLMVDEEQTVPFALRDENLKGVVYTTRPLREAETYRMRVRASSYSANGTIEYQTTFIVYIAVSAYPY 2040 13 - 132 118 54 46 1.958 2.003 2.235 68 70 67 * * * 2.065333333 0.148648355 sp|Q96RW7|HMCN1_HUMAN 100 0 gi|16551710|dbj|BAB71154.1| unnamed protein product [Homo sapiens] 100 0 sp|Q96RW7|HMCN1_HUMAN Hemicentin-1 OS=Homo sapiens GN=HMCN1 PE=1 SV=2 99.27 0 H2Q0S6 H2Q0S6_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000143341 PE=4 SV=1 - - - - - - - K12567|1|0.0|1184|bta:540561|titin [EC:2.7.11.1] GO:0050896//response to stimulus;GO:0007601//visual perception GO:0005509//calcium ion binding GO:0005604//basement membrane 416 sp|Q9UBX1|CATF_HUMAN Cathepsin F OS=Homo sapiens GN=CTSF PE=1 SV=1 62173 MAPWLQLLSLLGLLPGAVAAPAQPRAASFQAWGPPSPELLAPTRFALEMFNRGRAAGTRAVLGLVRGRVRRAGQGSLYSLEATLEEPPCNDPMVCRLPVSKKTLLCSFQVLDELGRHVLLRKDCGPVDTKVPGAGEPKSAFTQGSAMISSLSQNHPDNRNETFSSVISLLNEDPLSQDLPVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASSAVVD 407 11.8 - 15 15 5 5 1.257 1.24 1.053 9 8 6 - - - 1.183333333 0.113191578 sp|Q9UBX1|CATF_HUMAN 100 2.00E-180 gi|3916214|gb|AAC78839.1| cathepsin F [Homo sapiens] 100 0 sp|Q9UBX1|CATF_HUMAN Cathepsin F OS=Homo sapiens GN=CTSF PE=1 SV=1 100 4.00E-64 E9PSC2 E9PSC2_HUMAN Cathepsin F (Fragment) OS=Homo sapiens GN=CTSF PE=4 SV=1 AF1946_2 71.2 4.00E-12 COG4870 Cysteine protease O Posttranslational modification, protein turnover, chaperones ; K01373|1|0.0|889|hsa:8722|cathepsin F [EC:3.4.22.41] GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006508//proteolysis GO:0004197//cysteine-type endopeptidase activity GO:0043202//lysosomal lumen 417 tr|B4DUJ0|B4DUJ0_HUMAN cDNA FLJ60895, highly similar to Proteasome inhibitor PI31 subunit OS=Homo sapiens PE=2 SV=1 21211 MILNVLEYGSQQVADLTLNLDDYIDAEHLGDFHRTYKNSEELRSRIVSGIITPIHEQWEKANVSSPHREFPPATAREVDPLRIPPHHPHTSRQPPWCDPLGPFVVGGEDLDPFGPRRGGMIVDPLRSCFPRALIDPSSGLPNRLPPGAVPPGARFDPFGPIGTSPPGPNPDHLPPPGYDDMYL 76 14.8 2 3 3 2 2 1.429 0.837 1.154 2 2 2 - - - 1.14 0.296248207 tr|B4DUJ0|B4DUJ0_HUMAN 100 3.00E-92 gi|194374079|dbj|BAG62352.1| unnamed protein product [Homo sapiens] 99.45 2.00E-92 sp|Q92530|PSMF1_HUMAN Proteasome inhibitor PI31 subunit OS=Homo sapiens GN=PSMF1 PE=1 SV=2 100 8.00E-49 Q5QPM9 Q5QPM9_HUMAN Proteasome (Prosome, macropain) inhibitor subunit 1 (PI31) (Fragment) OS=Homo sapiens GN=PSMF1 PE=2 SV=1 - - - - - - - K06700|1|2e-92|337|hsa:9491|proteasome inhibitor subunit 1 (PI31) GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0010951//negative regulation of endopeptidase activity;GO:0016032//viral reproduction;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0005515//protein binding;GO:0004866//endopeptidase inhibitor activity GO:0005654//nucleoplasm;GO:0005839//proteasome core complex;GO:0005829//cytosol 418 tr|B5MBX2|B5MBX2_HUMAN Transcobalamin-2 OS=Homo sapiens GN=TCN2 PE=4 SV=1 53348 MRHLGAFLFLLGVLGALTEMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRLSSLQAGTKEDLYLHSLKLGYQQCLLGEDDGDCQGKPSMGQLALYLLALRANCEFVRGHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLLYAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVREEILKAQTPEGHFGNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETIELRLVSW 198 15.1 1 10 10 5 5 1.292 1.481 1.734 4 5 5 - - - 1.502333333 0.221770903 tr|B5MBX2|B5MBX2_HUMAN 99.06 0 gi|21071010|ref|NP_000346.2| transcobalamin-2 isoform 1 precursor [Homo sapiens] >gi|224471876|sp|P20062.3|TCO2_HUMAN RecName: Full=Transcobalamin-2; Short=TC-2; AltName: Full=Transcobalamin II; Short=TC II; Short=TCII; Flags: Precursor >gi|298316|gb|AAB25526.1| transcobalamin II, TC II [human, endothelial cells, Peptide, 427 aa] >gi|444771|prf||1908207A transcobalamin II 99.06 0 sp|P20062|TCO2_HUMAN Transcobalamin-2 OS=Homo sapiens GN=TCN2 PE=1 SV=3 100 0 B5MBX2 B5MBX2_HUMAN Transcobalamin-2 OS=Homo sapiens GN=TCN2 PE=4 SV=1 - - - - - - - K14619|1|0.0|812|hsa:6948|transcobalamin-2 GO:0006824//cobalt ion transport;GO:0015889//cobalamin transport;GO:0009235//cobalamin metabolic process GO:0046872//metal ion binding;GO:0031419//cobalamin binding GO:0005615//extracellular space 419 tr|A0A024RB53|A0A024RB53_HUMAN Heterogeneous nuclear ribonucleoprotein A1, isoform CRA_a OS=Homo sapiens GN=HNRPA1 PE=4 SV=1 40069 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF 79 15 6 8 7 5 4 1.129 1.299 0.917 3 3 3 - - - 1.115 0.19138443 tr|A0A024RB53|A0A024RB53_HUMAN 100 5.00E-112 gi|470595967|ref|XP_004310845.1| PREDICTED: heterogeneous nuclear ribonucleoprotein A1 isoform 2 [Tursiops truncatus] 100 7.00E-113 sp|P49312|ROA1_MOUSE Heterogeneous nuclear ribonucleoprotein A1 OS=Mus musculus GN=Hnrnpa1 PE=1 SV=2 100 4.00E-111 G3IGL0 G3IGL0_CRIGR Putative heterogeneous nuclear ribonucleoprotein A1-like protein 3 OS=Cricetulus griseus GN=I79_022927 PE=4 SV=1 SPAC140.02 73.6 5.00E-13 COG0724 RNA-binding proteins (RRM domain) R General function prediction only ; K12741|1|7e-115|413|ecb:100034153|heterogeneous nuclear ribonucleoprotein A1/A3 GO:0006405//RNA export from nucleus;GO:0051170//nuclear import;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0019048//virus-host interaction;GO:0051028//mRNA transport GO:0003727//single-stranded RNA binding;GO:0000166//nucleotide binding;GO:0003697//single-stranded DNA binding GO:0005730//nucleolus;GO:0071013//catalytic step 2 spliceosome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm 420 sp|P13797|PLST_HUMAN Plastin-3 OS=Homo sapiens GN=PLS3 PE=1 SV=4 86794 MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKRV 1337 35.4 - 79 65 20 17 0.83 0.838 0.89 39 40 40 * * - 0.852666667 0.032578111 sp|P13797|PLST_HUMAN 100 0 gi|14250317|gb|AAH08588.1| Similar to plastin 3 (T isoform), partial [Homo sapiens] 100 0 sp|P13797|PLST_HUMAN Plastin-3 OS=Homo sapiens GN=PLS3 PE=1 SV=4 100 0 A8K579 A8K579_HUMAN Plastin 3 (T isoform) OS=Homo sapiens GN=PLS3 PE=2 SV=1 SPBC1778.06c 434 2.00E-121 COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) Z Cytoskeleton ; K10382|1|4e-12|73.9|mgp:100542468|dystonin!K06115|2|8e-12|72.8|bfo:BRAFLDRAFT_93030|spectrin beta - GO:0003779//actin binding;GO:0005509//calcium ion binding GO:0005737//cytoplasm;GO:0032420//stereocilium 421 tr|A0A087WTX5|A0A087WTX5_HUMAN Ig kappa chain C region OS=Homo sapiens GN=IGKC PE=4 SV=1 30209 MDMRVPAQLLGLLLLWFPGSRCDIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQANSFPLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC 817 22 14 44 8 3 2 0.871 2.226 0.868 6 3 3 - * - 1.321666667 0.783177077 tr|A0A087WTX5|A0A087WTX5_HUMAN 99.53 1.00E-113 gi|21669297|dbj|BAC01673.1| immunoglobulin kappa light chain VLJ region [Homo sapiens] 100 1.00E-49 sp|P01834|IGKC_HUMAN Ig kappa chain C region OS=Homo sapiens GN=IGKC PE=1 SV=1 96.91 1.00E-46 G3QD17 G3QD17_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla PE=4 SV=1 - - - - - - - K06554|1|4e-36|151|mcc:100430606|immunoglobulin lambda-like polypeptide 1!K06553|4|1e-19|97.1|ecb:100072385|pre-B lymphocyte gene GO:0045087//innate immune response;GO:0006958//complement activation, classical pathway GO:0003823//antigen binding GO:0005886//plasma membrane;GO:0005576//extracellular region 422 sp|Q05707|COEA1_HUMAN Collagen alpha-1(XIV) chain OS=Homo sapiens GN=COL14A1 PE=1 SV=3 220944 MKIFQRKMRYWLLPPFLAIVYFCTIVQGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVKFVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHRHATAYRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIMEKTQSLPTRPPTFPPTIPPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIPKVIVVITDGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIEDELITFVCETASATCPVVHKDGIDLAGFKMMEMFGLVEKDFSSVEGVSMEPGTFNVFPCYQLHKDALVSQPTRYLHPEGLPSDYTISFLFRILPDTPQEPFALWEILNKNSDPLVGVILDNGGKTLTYFNYDQSGDFQTVTFEGPEIRKIFYGSFHKLHIVVSETLVKVVIDCKQVGEKAMNASANITSDGVEVLGKMVRSRGPGGNSAPFQLQMFDIVCSTSWANTDKCCELPGLRDDESCPDLPHSCSCSETNEVALGPAGPPGGPGLRGPKGQQGEPGPKGPDGPRGEIGLPGPQGPPGPQGPSGLSIQGMPGMPGEKGEKGDTGLPGPQGIPGGVGSPGRDGSPGQRGLPGKDGSSGPPGPPGPIGIPGTPGVPGITGSMGPQGALGPPGVPGAKGERGERGDLQSQAMVRSVARQVCEQLIQSHMARYTAILNQIPSHSSSIRTVQGPPGEPGRPGSPGAPGEQGPPGTPGFPGNAGVPGTPGERGLTGIKGEKGNPGVGTQGPRGPPGPAGPSGESRPGSPGPPGSPGPRGPPGHLGVPGPQGPSGQPGYCDPSSCSAYGVRAPHPDQPEFTPVQDELEAMELWGPGV 147 5.1 - 12 12 8 8 2.143 3.826 1.737 4 4 4 - * - 2.568666667 1.107643595 sp|Q05707|COEA1_HUMAN 100 0 gi|2065167|emb|CAA72402.1| collagen type XIV [Homo sapiens] 100 0 sp|Q05707|COEA1_HUMAN Collagen alpha-1(XIV) chain OS=Homo sapiens GN=COL14A1 PE=1 SV=3 100 0 Q4G0W3 Q4G0W3_HUMAN COL14A1 protein OS=Homo sapiens GN=COL14A1 PE=2 SV=1 - - - - - - - K08133|1|0.0|3143|hsa:7373|collagen, type XIV, alpha GO:0016337//cell-cell adhesion;GO:0030199//collagen fibril organization GO:0005518//collagen binding;GO:0030674//protein binding, bridging;GO:0005201//extracellular matrix structural constituent GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005596//collagen type XIV 423 sp|P27658|CO8A1_HUMAN Collagen alpha-1(VIII) chain OS=Homo sapiens GN=COL8A1 PE=1 SV=2 88033 MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM 575 16.9 - 28 28 8 8 1.141 1.111 1.025 19 20 19 - - - 1.092333333 0.060210741 sp|P27658|CO8A1_HUMAN 100 4.00E-06 gi|155372079|ref|NP_001094646.1| collagen alpha-1(VIII) chain precursor [Bos taurus] >gi|154757532|gb|AAI51645.1| COL8A1 protein [Bos taurus] >gi|296491533|tpg|DAA33576.1| TPA: alpha 1 type VIII collagen [Bos taurus] 100 2.00E-90 sp|P27658|CO8A1_HUMAN Collagen alpha-1(VIII) chain OS=Homo sapiens GN=COL8A1 PE=1 SV=2 100 6.00E-89 A1KY36 A1KY36_HUMAN Cell proliferation-inducing protein 41 OS=Homo sapiens PE=2 SV=1 - - - - - - - K07296|1|6e-27|123|acs:100568236|adiponectin GO:0001525//angiogenesis;GO:0010811//positive regulation of cell-substrate adhesion;GO:0048593//camera-type eye morphogenesis;GO:0050673//epithelial cell proliferation;GO:0030198//extracellular matrix organization - GO:0005591//collagen type VIII;GO:0005604//basement membrane;GO:0005788//endoplasmic reticulum lumen 424 sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 OS=Homo sapiens GN=PDIA6 PE=1 SV=1 57617 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDVELDDLGKDEL 276 16.8 - 14 14 5 5 0.942 1.015 0.879 9 9 9 - - - 0.945333333 0.068061247 sp|Q15084|PDIA6_HUMAN 100 8.00E-139 gi|119621354|gb|EAX00949.1| protein disulfide isomerase family A, member 6, isoform CRA_a [Homo sapiens] 100 0 sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 OS=Homo sapiens GN=PDIA6 PE=1 SV=1 100 0 B5MCQ5 B5MCQ5_HUMAN Protein disulfide-isomerase A6 OS=Homo sapiens GN=PDIA6 PE=3 SV=1 SPAC17H9.14c 119 1.00E-26 COG0526 Thiol-disulfide isomerase and thioredoxins OC Posttranslational modification, protein turnover, chaperones ; Energy production and conversion ; K09584|1|0.0|779|hsa:10130|protein disulfide-isomerase A6 [EC:5.3.4.1] GO:0006457//protein folding;GO:0070527//platelet aggregation;GO:0045454//cell redox homeostasis;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006662//glycerol ether metabolic process GO:0015035//protein disulfide oxidoreductase activity;GO:0005515//protein binding;GO:0003756//protein disulfide isomerase activity;GO:0009055//electron carrier activity GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005788//endoplasmic reticulum lumen;GO:0042470//melanosome;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane 425 sp|O00300|TR11B_HUMAN Tumor necrosis factor receptor superfamily member 11B OS=Homo sapiens GN=TNFRSF11B PE=1 SV=3 59590 MNNLLCCALVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNICSGNSESTQKCGIDVTLCEEAFFRFAVPTKFTPNWLSVLVDNLPGTKVNAESVERIKRQHSSQEQTFQLLKLWKHQNKDQDIVKKIIQDIDLCENSVQRHIGHANLTFEQLRSLMESLPGKKVGAEDIEKTIKACKPSDQILKLLSLWRIKNGDQDTLKGLMHALKHSKTYHFPKTVTQSLKKTIRFLHSFTMYKLYQKLFLEMIGNQVQSVKISCL 395 10.2 - 15 15 3 3 0.874 0.854 0.721 13 13 11 * - * 0.816333333 0.083164496 sp|O00300|TR11B_HUMAN 100 3.00E-95 gi|394986062|pdb|3URF|Z Chain Z, Human RanklOPG COMPLEX 100 0 sp|O00300|TR11B_HUMAN Tumor necrosis factor receptor superfamily member 11B OS=Homo sapiens GN=TNFRSF11B PE=1 SV=3 99.5 0 H2QWM3 H2QWM3_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000164761 PE=4 SV=1 - - - - - - - K05148|1|0.0|797|hsa:4982|tumor necrosis factor receptor superfamily member 11B GO:0032026//response to magnesium ion;GO:0042489//negative regulation of odontogenesis of dentin-containing tooth;GO:0043627//response to estrogen stimulus;GO:0006915//apoptotic process;GO:0007584//response to nutrient;GO:0001501//skeletal system development;GO:0007165//signal transduction;GO:0042493//response to drug;GO:0046685//response to arsenic-containing substance;GO:0045779//negative regulation of bone resorption;GO:0030198//extracellular matrix organization GO:0004872//receptor activity;GO:0005125//cytokine activity GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 426 tr|J3KMX3|J3KMX3_HUMAN Alpha-fetoprotein OS=Homo sapiens GN=AFP PE=1 SV=1 85062 MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATYKEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEGRHNCFLAHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILLWAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTKLSQKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKITECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSRRHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADIIIGHLCIRHEMTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQAQGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGKRRQNESFIRCELFSLILTDLTLFVN 270 5.5 3 14 14 3 3 0.601 0.588 0.694 10 9 10 * * * 0.627666667 0.057812917 tr|J3KMX3|J3KMX3_HUMAN 99.67 0 gi|4501989|ref|NP_001125.1| alpha-fetoprotein precursor [Homo sapiens] >gi|120042|sp|P02771.1|FETA_HUMAN RecName: Full=Alpha-fetoprotein; AltName: Full=Alpha-1-fetoprotein; AltName: Full=Alpha-fetoglobulin; Flags: Precursor >gi|178236|gb|AAB58754.1| alpha-fetoprotein [Homo sapiens] >gi|20379787|gb|AAH27881.1| Alpha-fetoprotein [Homo sapiens] >gi|119626086|gb|EAX05681.1| alpha-fetoprotein [Homo sapiens] 99.67 0 sp|P02771|FETA_HUMAN Alpha-fetoprotein OS=Homo sapiens GN=AFP PE=1 SV=1 100 3.00E-13 Q8HZ92 Q8HZ92_9PRIM Alpha-fetoprotein (Fragment) OS=Macaca sp. PE=4 SV=1 - - - - - - - K01883|1|8e-93|341|xtr:448227|cysteinyl-tRNA synthetase [EC:6.1.1.16]!K12258|3|3e-27|124|xla:495173|vitamin D-binding protein GO:0006810//transport;GO:0031100//organ regeneration;GO:0001542//ovulation from ovarian follicle;GO:0001889//liver development;GO:0031016//pancreas development;GO:0060395//SMAD protein signal transduction;GO:0042448//progesterone metabolic process;GO:0010033//response to organic substance GO:0046872//metal ion binding GO:0005615//extracellular space;GO:0005737//cytoplasm 427 tr|D3DSQ1|D3DSQ1_HUMAN N-acylsphingosine amidohydrolase (Acid ceramidase) 1, isoform CRA_c OS=Homo sapiens GN=ASAH1 PE=4 SV=1 70264 MNCCIGLGEKARGSHRASYPSLSALFTEASILGFGSFAVKAQVGNQQLGGPEWIRFSLTPRPLNCSLSLTPRGQRWVRVGCYISVETLWIRFVGTEDAWVRGTGCTRLLEAPHRGATGRGSRGGGGVACPRPSRLFFASAGVRGVALAARAMPGRSCVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRWHELMLDKAPMLKVIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDAMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW 766 14.1 2 55 55 8 8 1.205 0.889 0.994 27 29 28 - * - 1.029333333 0.160935805 tr|D3DSQ1|D3DSQ1_HUMAN 100 8.00E-16 gi|189011550|ref|NP_001120977.1| acid ceramidase isoform c [Homo sapiens] 99.24 0 sp|Q13510|ASAH1_HUMAN Acid ceramidase OS=Homo sapiens GN=ASAH1 PE=1 SV=5 100 3.00E-15 E9PDS0 E9PDS0_HUMAN Acid ceramidase subunit beta OS=Homo sapiens GN=ASAH1 PE=4 SV=1 - - - - - - - K12348|1|0.0|773|ptr:464022|acid ceramidase [EC:3.5.1.23] GO:0006687//glycosphingolipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0010033//response to organic substance;GO:0044281//small molecule metabolic process;GO:0030324//lung development;GO:0006672//ceramide metabolic process GO:0017040//ceramidase activity GO:0043202//lysosomal lumen 428 tr|Q69YJ3|Q69YJ3_HUMAN Putative uncharacterized protein DKFZp762L185 (Fragment) OS=Homo sapiens GN=DKFZp762L185 PE=2 SV=1 153658 EQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLRSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVIGNINDVEFGIAFLNATITDSPNSDTRIIRAKITNVPRSLGSAMRKIVSILNPIYWTTAKEIGEAVNGFTLTNAVFKRETQVEFATGEILQMSHIARGLDSDGSLLLDIVVSGYVLQLQSPAEVTVKDYTEDYIQTGPGQLYAYSTRLFTIDGISIPYTWNHTVFYDQAQGRMPFLVETLHASSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLECALSPYALEYKLVSLPFGIATNQDLIRLVAYTQDGVMHPRTTFLMVDEEQTVPFALRDENLKGVVYTTRPLREAETYRMRVRASSYSANGTIEYQTTFIVYIAVSAYPY 308 10.4 - 16 2 9 1 1.259 1.406 1.411 2 2 2 - - - 1.358666667 0.086350063 tr|Q69YJ3|Q69YJ3_HUMAN 100 0 gi|50949511|emb|CAH10605.1| hypothetical protein [Homo sapiens] 97.88 0 sp|Q96RW7|HMCN1_HUMAN Hemicentin-1 OS=Homo sapiens GN=HMCN1 PE=1 SV=2 100 3.00E-141 Q5TCP6 Q5TCP6_HUMAN Hemicentin 1 (Fragment) OS=Homo sapiens GN=HMCN1 PE=2 SV=1 - - - - - - - K06841|1|7e-70|266|dre:561295|semaphorin 5 GO:0050896//response to stimulus;GO:0007601//visual perception GO:0005509//calcium ion binding GO:0005604//basement membrane 429 tr|D6RF35|D6RF35_HUMAN Vitamin D-binding protein OS=Homo sapiens GN=GC PE=1 SV=1 67663 MKRVLVLLLAVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCCSINSPPLYCDSETRVGATQGNDL 764 8.2 1 19 19 2 2 0.825 0.579 0.667 17 16 16 * * * 0.690333333 0.12464884 tr|D6RF35|D6RF35_HUMAN 100 8.00E-102 gi|297673695|ref|XP_002814890.1| PREDICTED: vitamin D-binding protein-like, partial [Pongo abelii] 99.57 0 sp|P02774|VTDB_HUMAN Vitamin D-binding protein OS=Homo sapiens GN=GC PE=1 SV=1 100 5.00E-79 D6RF20 D6RF20_HUMAN Vitamin D-binding protein (Fragment) OS=Homo sapiens GN=GC PE=4 SV=1 - - - - - - - K12258|1|0.0|907|hsa:2638|vitamin D-binding protein GO:0050728//negative regulation of inflammatory response;GO:0043687//post-translational protein modification;GO:0035307//positive regulation of protein dephosphorylation;GO:0009790//embryo development;GO:0007596//blood coagulation;GO:0071356//cellular response to tumor necrosis factor;GO:0046512//sphingosine biosynthetic process;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0051180//vitamin transport;GO:0046513//ceramide biosynthetic process;GO:0043407//negative regulation of MAP kinase activity;GO:0042359//vitamin D metabolic process;GO:0008219//cell death;GO:0005975//carbohydrate metabolic process;GO:0032571//response to vitamin K;GO:0023021//termination of signal transduction;GO:0007565//female pregnancy;GO:0032355//response to estradiol stimulus;GO:0032715//negative regulation of interleukin-6 production;GO:0006680//glucosylceramide catabolic process;GO:0007595//lactation;GO:0006644//phospholipid metabolic process;GO:0007040//lysosome organization GO:0005102//receptor binding;GO:0008488//gamma-glutamyl carboxylase activity;GO:0004348//glucosylceramidase activity;GO:0005499//vitamin D binding;GO:0051183//vitamin transporter activity;GO:0043169//cation binding;GO:0003779//actin binding GO:0005829//cytosol;GO:0005615//extracellular space;GO:0030424//axon;GO:0043202//lysosomal lumen;GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral to membrane;GO:0005765//lysosomal membrane;GO:0005789//endoplasmic reticulum membrane 430 tr|A5PKX5|A5PKX5_HUMAN Alpha-mannosidase OS=Homo sapiens GN=MAN2A1 PE=2 SV=1 152629 MKLSRQFTVFGSAIFCVVIFSLYLMLDRGHLDYPRNPRREGSFPQGQLSMLQEKIDHLERLLAENNEIISNIRDSVINLSESVEDGPKSSQSNFSQGAGSHLLPSQLSLSVDTADCLFASQSGSHNSDVQMLDVYSLISFDNPDGGVWKQGFDITYESNEWDTEPLQVFVVPHSHNDPGWLKTFNDYFRDKTQYIFNNMVLKLKEDSRRKFIWSEISYLSKWWDIIDIQKKDAVKSLIENGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENNIGVKPRSGWAIDPFGHSPTMAYLLNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQNWDLGSVTDILCHMMPFYSYDIPHTCGPDPKICCQFDFKRLPGGRFGCPWGVPPETIHPGNVQSRARMLLDQYRKKSKLFRTKVLLAPLGDDFRYCEYTEWDLQFKNYQQLFDYMNSQSKFKVKIQFGTLSDFFDALDKADETQRDKGQSMFPVLSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESHLRAAEILYYFALRQAHKYKINKFLSSSLYTALTEARRNLGLFQHHDAITGTAKDWVVVDYGTRPFHSLMVLEKIIGNSAFLLILKDKLTYDSYSPDTFLEMDLKQKSQDSLPQKNIIRLSAEPRYLVVYNPLEQDRISLVSVYVSSPTVQVFSASGKPVEVQVSAVWDTANTISETAYEISFRAHIPPLGLKVYKILESASSNSHLADYVLYKNKVEDSGIFTIKNMINTEEGITLENSFVLLRFDQTGLMKQMMTKEDGKHHEVNVQFSWYGTTIKRDKSGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYSEVTCFFDHVTHRVRLYHIQGIEGQSVEVSNIVDIRKVYNREIAMKISSDIKSQNRFYTDLNGYQIQPRMTLSKLPLQANVYPMTTMAYIQDAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQDNKITANLFRILLEKRSAVNTEEEKKSVSYPSLLSHITSSLMNHPVIPMANKFSPTLELQGEFSPLQSSLPCDIHLVNLRTIQSKVGNGHSNEAALILHRKGFDCRFSSKGTGLFCSTTQGKILVQKLLNKFIVESLTPSSLSLMHSPPGTQNISEINLSPMEISTFRIQLR 58 4.2 1 5 5 5 5 0.989 0.796 1.376 2 2 2 - - - 1.053666667 0.295357975 tr|A5PKX5|A5PKX5_HUMAN 100 7.00E-19 gi|297294814|ref|XP_002804520.1| PREDICTED: alpha-mannosidase 2-like [Macaca mulatta] 99.83 0 sp|Q16706|MA2A1_HUMAN Alpha-mannosidase 2 OS=Homo sapiens GN=MAN2A1 PE=1 SV=2 100 0 A5PKX5 A5PKX5_HUMAN MAN2A1 protein OS=Homo sapiens GN=MAN2A1 PE=2 SV=1 MT0676 78.2 7.00E-14 COG0383 Alpha-mannosidase G Carbohydrate transport and metabolism ; K01231|1|0.0|2376|hsa:4124|alpha-mannosidase II [EC:3.2.1.114] GO:0006491//N-glycan processing;GO:0048286//lung alveolus development;GO:0006013//mannose metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0001889//liver development;GO:0043687//post-translational protein modification;GO:0007005//mitochondrion organization;GO:0007033//vacuole organization;GO:0007585//respiratory gaseous exchange;GO:0001701//in utero embryonic development GO:0008270//zinc ion binding;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0004572//mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity;GO:0030246//carbohydrate binding GO:0016021//integral to membrane;GO:0000139//Golgi membrane 431 tr|Q6ZN40|Q6ZN40_HUMAN Tropomyosin 1 (Alpha), isoform CRA_f OS=Homo sapiens GN=TPM1 PE=1 SV=1 50264 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 1702 18.1 - 108 2 7 1 0.649 0.476 0.474 2 2 2 * - - 0.533 0.100463924 tr|Q6ZN40|Q6ZN40_HUMAN 100 6.00E-127 gi|119598030|gb|EAW77624.1| tropomyosin 1 (alpha), isoform CRA_f [Homo sapiens] 84.8 8.00E-69 sp|P67937|TPM4_PIG Tropomyosin alpha-4 chain OS=Sus scrofa GN=TPM4 PE=1 SV=3 100 2.00E-126 G3RWR8 G3RWR8_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=TPM1 PE=3 SV=1 - - - - - - - K10373|1|3e-105|382|mgp:100549276|tropomyosin 1 GO:0034614//cellular response to reactive oxygen species;GO:0001701//in utero embryonic development;GO:0032781//positive regulation of ATPase activity;GO:0060048//cardiac muscle contraction;GO:0030336//negative regulation of cell migration;GO:0045785//positive regulation of cell adhesion;GO:0051693//actin filament capping;GO:0006937//regulation of muscle contraction;GO:0030049//muscle filament sliding;GO:0045214//sarcomere organization;GO:0031529//ruffle organization;GO:0042060//wound healing;GO:0051496//positive regulation of stress fiber assembly;GO:0003065//positive regulation of heart rate by epinephrine;GO:0055010//ventricular cardiac muscle tissue morphogenesis GO:0042803//protein homodimerization activity;GO:0047485//protein N-terminus binding;GO:0005200//structural constituent of cytoskeleton;GO:0051015//actin filament binding;GO:0008307//structural constituent of muscle GO:0032059//bleb;GO:0005862//muscle thin filament tropomyosin;GO:0005829//cytosol;GO:0031941//filamentous actin;GO:0001725//stress fiber;GO:0032587//ruffle membrane 432 sp|Q9NQ88|TIGAR_HUMAN Fructose-2,6-bisphosphatase TIGAR OS=Homo sapiens GN=TIGAR PE=1 SV=1 36222 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFIINFEEGREVKPTVQCICMNLQDHLNGLTETR 79 6.3 - 2 2 1 1 0.644 0.926 --- 2 2 1 - - - 0.785 0.199404112 sp|Q9NQ88|TIGAR_HUMAN 100 2.00E-158 gi|9966849|ref|NP_065108.1| fructose-2,6-bisphosphatase TIGAR [Homo sapiens] >gi|74734311|sp|Q9NQ88.1|TIGAR_HUMAN RecName: Full=Fructose-2,6-bisphosphatase TIGAR; AltName: Full=TP53-induced glycolysis and apoptosis regulator >gi|15214429|gb|AAH12340.1| Chromosome 12 open reading frame 5 [Homo sapiens] >gi|37694056|gb|AAQ98969.1| transactivated by NS3TP2 protein [Homo sapiens] >gi|119609255|gb|EAW88849.1| chromosome 12 open reading frame 5, isoform CRA_a [Homo sapiens] 100 2.00E-159 sp|Q9NQ88|TIGAR_HUMAN Fructose-2,6-bisphosphatase TIGAR OS=Homo sapiens GN=TIGAR PE=1 SV=1 99.63 9.00E-158 G3RM37 G3RM37_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=C12orf5 PE=4 SV=1 Cgl2299 78.6 1.00E-14 COG0406 Fructose-2,6-bisphosphatase G Carbohydrate transport and metabolism ; K14634|1|2e-159|561|hsa:57103|fructose-2,6-bisphosphatase [EC:3.1.3.46] - GO:0004331//fructose-2,6-bisphosphate 2-phosphatase activity GO:0005622//intracellular 433 sp|O76076|WISP2_HUMAN WNT1-inducible-signaling pathway protein 2 OS=Homo sapiens GN=WISP2 PE=1 SV=1 29677 MRGTPKTHLLAFSLLCLLSKVRTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCGQGGGLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLETQRRLCLSRPCPPSRGRSPQNSAF 84 15.6 - 2 2 2 2 0.761 1.11 1.34 2 2 2 - - - 1.070333333 0.291531016 sp|O76076|WISP2_HUMAN 100 4.00E-88 gi|4507923|ref|NP_003872.1| WNT1-inducible-signaling pathway protein 2 precursor [Homo sapiens] >gi|24211561|sp|O76076.1|WISP2_HUMAN RecName: Full=WNT1-inducible-signaling pathway protein 2; Short=WISP-2; AltName: Full=CCN family member 5; AltName: Full=Connective tissue growth factor-like protein; Short=CTGF-L; AltName: Full=Connective tissue growth factor-related protein 58; Flags: Precursor >gi|3328192|gb|AAC26794.1| connective tissue growth factor-related protein precursor [Homo sapiens] >gi|3462836|gb|AAC70350.1| connective tissue growth factor-like protein precursor [Homo sapiens] >gi|4028583|gb|AAC96322.1| connective tissue growth factor related protein WISP-2 [Homo sapiens] >gi|17389483|gb|AAH17782.1| WNT1 inducible signaling pathway protein 2 [Homo sapiens] >gi|37182948|gb|AAQ89274.1| WISP-2 [Homo sapiens] >gi|39992599|gb|AAH64379.1| WNT1 inducible signaling pathway protein 2 [Homo sapiens] >gi|119596308|gb|EAW75902.1| WNT1 inducible signaling pathway protein 2, isoform CRA_a [Homo sapiens] >gi|119596309|gb|EAW75903.1| WNT1 inducible signaling pathway protein 2, isoform CRA_a [Homo sapiens] 100 5.00E-89 sp|O76076|WISP2_HUMAN WNT1-inducible-signaling pathway protein 2 OS=Homo sapiens GN=WISP2 PE=1 SV=1 99.6 8.00E-87 H2R8X7 H2R8X7_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000064205 PE=4 SV=1 - - - - - - - K06827|1|5e-44|177|xtr:496678|connective tissue growth factor GO:0001558//regulation of cell growth;GO:0007267//cell-cell signaling;GO:0007165//signal transduction GO:0005520//insulin-like growth factor binding GO:0005615//extracellular space;GO:0005886//plasma membrane 434 sp|Q14108|SCRB2_HUMAN Lysosome membrane protein 2 OS=Homo sapiens GN=SCARB2 PE=1 SV=2 >tr|A0A024RDG6|A0A024RDG6_HUMAN Scavenger receptor class B, member 2, isoform CRA_a OS=Homo sapiens GN=SCARB2 PE=4 SV=1 62317 MGRCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTLNIPVLTVIEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHVFRPDISPYFGLFYEKNGTNDGDYVFLTGEDSYLNFTKIVEWNGKTSLDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTLIITNIPYIIMALGVFFGLVFTWLACKGQGSMDEGTADERAPLIRT 56 6.3 - 4 4 3 3 0.685 0.63 0.692 2 2 2 - - - 0.669 0.033955854 sp|Q14108|SCRB2_HUMAN 100 0 gi|5031631|ref|NP_005497.1| lysosome membrane protein 2 isoform 1 precursor [Homo sapiens] >gi|2498525|sp|Q14108.2|SCRB2_HUMAN RecName: Full=Lysosome membrane protein 2; AltName: Full=85 kDa lysosomal membrane sialoglycoprotein; Short=LGP85; AltName: Full=CD36 antigen-like 2; AltName: Full=Lysosome membrane protein II; Short=LIMP II; AltName: Full=Scavenger receptor class B member 2; AltName: CD_antigen=CD36 >gi|219703|dbj|BAA02177.1| 85kDa lysosomal sialoglycoprotein [Homo sapiens] >gi|18257312|gb|AAH21892.1| Scavenger receptor class B, member 2 [Homo sapiens] >gi|30582717|gb|AAP35585.1| scavenger receptor class B, member 2 [Homo sapiens] >gi|119626184|gb|EAX05779.1| scavenger receptor class B, member 2, isoform CRA_a [Homo sapiens] >gi|119626185|gb|EAX05780.1| scavenger receptor class B, member 2, isoform CRA_a [Homo sapiens] >gi|119626186|gb|EAX05781.1| scavenger receptor class B, member 2, isoform CRA_a [Homo sapiens] 100 0 sp|Q14108|SCRB2_HUMAN Lysosome membrane protein 2 OS=Homo sapiens GN=SCARB2 PE=1 SV=2 100 0 Q53Y63 Q53Y63_HUMAN Scavenger receptor class B, member 2 OS=Homo sapiens GN=SCARB2 PE=2 SV=1 - - - - - - - K12384|1|0.0|947|pon:100455864|lysosome membrane protein 2 GO:0007155//cell adhesion;GO:0006622//protein targeting to lysosome GO:0004872//receptor activity;GO:0019899//enzyme binding GO:0005887//integral to plasma membrane;GO:0043202//lysosomal lumen;GO:0005765//lysosomal membrane 435 sp|Q13162|PRDX4_HUMAN Peroxiredoxin-4 OS=Homo sapiens GN=PRDX4 PE=1 SV=1 >tr|V9HW63|V9HW63_HUMAN Epididymis secretory sperm binding protein Li 97n OS=Homo sapiens GN=HEL-S-97n PE=2 SV=1 35008 MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN 193 35.4 - 20 11 7 6 0.94 0.606 0.74 9 9 9 - * * 0.762 0.168083313 sp|Q13162|PRDX4_HUMAN 100 9.00E-141 gi|5453549|ref|NP_006397.1| peroxiredoxin-4 precursor [Homo sapiens] >gi|3024727|sp|Q13162.1|PRDX4_HUMAN RecName: Full=Peroxiredoxin-4; AltName: Full=Antioxidant enzyme AOE372; Short=AOE37-2; AltName: Full=Peroxiredoxin IV; Short=Prx-IV; AltName: Full=Thioredoxin peroxidase AO372; AltName: Full=Thioredoxin-dependent peroxide reductase A0372; Flags: Precursor >gi|799381|gb|AAB95175.1| antioxidant enzyme AOE37-2 [Homo sapiens] >gi|13177646|gb|AAH03609.1| Peroxiredoxin 4 [Homo sapiens] >gi|13937985|gb|AAH07107.1| Peroxiredoxin 4 [Homo sapiens] >gi|16876997|gb|AAH16770.1| Peroxiredoxin 4 [Homo sapiens] >gi|49456371|emb|CAG46506.1| PRDX4 [Homo sapiens] >gi|119619402|gb|EAW98996.1| peroxiredoxin 4 [Homo sapiens] 100 1.00E-141 sp|Q13162|PRDX4_HUMAN Peroxiredoxin-4 OS=Homo sapiens GN=PRDX4 PE=1 SV=1 99.63 1.00E-139 G3RXK5 G3RXK5_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=PRDX4 PE=4 SV=1 SPCC576.03c 249 5.00E-66 COG0450 Peroxiredoxin O Posttranslational modification, protein turnover, chaperones ; K03386|1|1e-141|502|hsa:10549|peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15] GO:0007252//I-kappaB phosphorylation;GO:0072593//reactive oxygen species metabolic process;GO:0055114//oxidation-reduction process GO:0005515//protein binding;GO:0008379//thioredoxin peroxidase activity GO:0005615//extracellular space;GO:0005739//mitochondrion 436 tr|H0YG03|H0YG03_HUMAN Microfibrillar-associated protein 5 (Fragment) OS=Homo sapiens GN=MFAP5 PE=4 SV=1 21097 XLAAFIITSDWIPLGVNSQRGDDVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDDLASLSEKNTTAECWDEKFTCTRLYSVHRPVKQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENVDLQRPNGL 61 7.4 7 4 4 1 1 1.388 1.347 1.906 3 3 3 - - * 1.547 0.311578241 tr|H0YG03|H0YG03_HUMAN 100 7.00E-92 gi|4505089|ref|NP_003471.1| microfibrillar-associated protein 5 precursor [Homo sapiens] >gi|2498553|sp|Q13361.1|MFAP5_HUMAN RecName: Full=Microfibrillar-associated protein 5; Short=MFAP-5; AltName: Full=MP25; AltName: Full=Microfibril-associated glycoprotein 2; Short=MAGP-2; Flags: Precursor >gi|1165212|gb|AAA96752.1| microfibril-associated glycoprotein-2 MAGP-2 [Homo sapiens] >gi|3983463|gb|AAC83942.1| microfibril-associated glycoprotein 2 [Homo sapiens] >gi|13543486|gb|AAH05901.1| MFAP5 protein [Homo sapiens] >gi|119609019|gb|EAW88613.1| microfibrillar associated protein 5, isoform CRA_a [Homo sapiens] >gi|119609020|gb|EAW88614.1| microfibrillar associated protein 5, isoform CRA_a [Homo sapiens] 100 1.00E-92 sp|Q13361|MFAP5_HUMAN Microfibrillar-associated protein 5 OS=Homo sapiens GN=MFAP5 PE=1 SV=1 100 9.00E-15 F5H413 F5H413_HUMAN Microfibrillar-associated protein 5 OS=Homo sapiens GN=MFAP5 PE=4 SV=1 - - - - - - - K10989|1|4e-29|127|tgu:100229705|activation-induced cytidine deaminase [EC:3.5.4.5] - GO:0005201//extracellular matrix structural constituent GO:0001527//microfibril 437 sp|O00469|PLOD2_HUMAN Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 OS=Homo sapiens GN=PLOD2 PE=1 SV=2 101496 MGGCTVKPQLLLLALVLHPWNPCLGADSEKPSSIPTDKLLVITVATKESDGFHRFMQSAKYFNYTVKVLGQGEEWRGGDGINSIGGGQKVRLMKEVMEHYADQDDLVVMFTECFDVIFAGGPEEVLKKFQKANHKVVFAADGILWPDKRLADKYPVVHIGKRYLNSGGFIGYAPYVNRIVQQWNLQDNDDDQLFYTKVYIDPLKREAINITLDHKCKIFQTLNGAVDEVVLKFENGKARAKNTFYETLPVAINGNGPTKILLNYFGNYVPNSWTQDNGCTLCEFDTVDLSAVDVHPNVSIGVFIEQPTPFLPRFLDILLTLDYPKEALKLFIHNKEVYHEKDIKVFFDKAKHEIKTIKIVGPEENLSQAEARNMGMDFCRQDEKCDYYFSVDADVVLTNPRTLKILIEQNRKIIAPLVTRHGKLWSNFWGALSPDGYYARSEDYVDIVQGNRVGVWNVPYMANVYLIKGKTLRSEMNERNYFVRDKLDPDMALCRNAREMGVFMYISNRHEFGRLLSTANYNTSHYNNDLWQIFENPVDWKEKYINRDYSKIFTENIVEQPCPDVFWFPIFSEKACDELVEEMEHYGKWSGGKHHDSRISGGYENVPTDDIHMKQVDLENVWLHFIREFIAPVTLKVFAGYYTKGFALLNFVVKYSPERQRSLRPHHDASTFTINIALNNVGEDFQGGGCKFLRYNCSIESPRKGWSFMHPGRLTHLHEGLPVKNGTRYIAVSFIDP 219 10.4 - 12 12 7 7 0.602 0.469 0.425 8 8 8 * * * 0.498666667 0.092153857 sp|O00469|PLOD2_HUMAN 100 0 gi|62089344|dbj|BAD93116.1| procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 isoform b variant [Homo sapiens] 100 0 sp|O00469|PLOD2_HUMAN Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 OS=Homo sapiens GN=PLOD2 PE=1 SV=2 100 5.00E-123 Q96AR9 Q96AR9_HUMAN PLOD2 protein (Fragment) OS=Homo sapiens GN=PLOD2 PE=2 SV=1 - - - - - - - K13645|1|0.0|1460|hsa:5352|procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 [EC:1.14.11.4] GO:0001666//response to hypoxia;GO:0006464//cellular protein modification process;GO:0032870//cellular response to hormone stimulus;GO:0030198//extracellular matrix organization GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0008475//procollagen-lysine 5-dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0005506//iron ion binding GO:0005581//collagen;GO:0030867//rough endoplasmic reticulum membrane 438 sp|Q9NZM1|MYOF_HUMAN Myoferlin OS=Homo sapiens GN=MYOF PE=1 SV=1 281731 MLRVIVESASNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLDFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATIDLVIGYDPPSAPHPNDLSGPSVPGMGGDGEEDEGDEDRLDNAVRGPGPKGPVGTVSEAQLARRLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRPVVKVHVCGQTHRTRIKRGNNPFFDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLMGEFKIDVGFVYDEPGHAVMRKWLLLNDPEDTSSGSKGYMKVSMFVLGTGDEPPPERRDRDNDSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASGGEVEDFSSSGTGAASYTVNTGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNTGKGEGVAYRGRILVELATFLEKTPPDKKLEPISNDDLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNKFDTTCKPLASTTQYSRAVFDGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTLLAMAERLQTNIEALKSGIQGKIPANQLAELWLKLIDEVIEDTRYTLPLTEGKANVTVLDTQIRKLRSRSLSQIHEAAVRMRSEATDVKSTLAEIEDWLDKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGENASGKYCGKTQTIFLKYPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQALMFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGEWIVDPERSLLTEADAGHTEFTDEVYQNESRYPGGDWKPAEDTYTDANGDKAASPSELTCPPGWEWEDDAWSYDINRAVDEKGWEYGITIPPDHKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELQDQEGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGDEKSLEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCYVYQARNLLALDKDSFSDPYAHICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPKVIMELFDNDQVGKDEFLGRSIFSPVVKLNSEMDITPKLLWHPVMNGDKACGDVLVTAELILRGKDGSNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSPSLVVECGGERVESVVIKNLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTIERLDRFRCDPYAGKEDIVPQLKASLLSAPPCRDIVIEMEDTKPLLASKLTEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLTDFSDTFKLYRGKSDENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQECTVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPTQLLQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRTQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVIIWNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDYLPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAKSPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEILNEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLFLLILLLFVAVLLYSLPNYLSMKIVKPNV 79 1.4 - 6 6 3 3 0.756 0.575 0.849 5 5 5 - * - 0.726666667 0.139335327 sp|Q9NZM1|MYOF_HUMAN 100 0 gi|7305053|ref|NP_038479.1| myoferlin isoform a [Homo sapiens] >gi|20139241|sp|Q9NZM1.1|MYOF_HUMAN RecName: Full=Myoferlin; AltName: Full=Fer-1-like protein 3 >gi|6731235|gb|AAF27176.1|AF182316_1 myoferlin [Homo sapiens] >gi|20521790|dbj|BAA86521.2| KIAA1207 protein [Homo sapiens] 100 0 sp|Q9NZM1|MYOF_HUMAN Myoferlin OS=Homo sapiens GN=MYOF PE=1 SV=1 99.85 0 F8W8J4 F8W8J4_HUMAN Myoferlin OS=Homo sapiens GN=MYOF PE=4 SV=1 SPCP31B10.06 53.9 3.00E-06 COG5038 Ca2+-dependent lipid-binding protein, contains C2 domain R General function prediction only ; K02677|1|2e-06|57.0|cqu:CpipJ_CPIJ005701|classical protein kinase C [EC:2.7.11.13] GO:0030947//regulation of vascular endothelial growth factor receptor signaling pathway;GO:0001778//plasma membrane repair;GO:0034605//cellular response to heat;GO:0008015//blood circulation;GO:0006936//muscle contraction GO:0005543//phospholipid binding GO:0030659//cytoplasmic vesicle membrane;GO:0031965//nuclear membrane;GO:0016021//integral to membrane;GO:0005901//caveola 439 tr|Q59EJ3|Q59EJ3_HUMAN Heat shock 70kDa protein 1A variant (Fragment) OS=Homo sapiens PE=2 SV=1 93532 LRSCCDSPLPFSRVTPVVPRLPRANLCGCRHRRVEFPASGRTELFSRIQCSVSSPQSQSRADREQGTGMAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGDTKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIESMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD 270 13.4 1 13 10 6 4 0.855 1.229 0.99 3 5 5 * - - 1.024666667 0.18939465 tr|Q59EJ3|Q59EJ3_HUMAN 100 0 gi|62089222|dbj|BAD93055.1| heat shock 70kDa protein 1A variant [Homo sapiens] 99.69 0 sp|Q5R7D3|HSP71_PONAB Heat shock 70 kDa protein 1 OS=Pongo abelii GN=HSPA1 PE=2 SV=1 100 0 Q59EJ3 Q59EJ3_HUMAN Heat shock 70kDa protein 1A variant (Fragment) OS=Homo sapiens PE=2 SV=1 SPAC13G7.02c 979 0 COG0443 Molecular chaperone O Posttranslational modification, protein turnover, chaperones ; K03283|1|0.0|1196|hsa:3303|heat shock 70kDa protein 1/8 GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0010467//gene expression;GO:0008285//negative regulation of cell proliferation;GO:0006402//mRNA catabolic process;GO:0045906//negative regulation of vasoconstriction;GO:0090084//negative regulation of inclusion body assembly;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030308//negative regulation of cell growth;GO:0000723//telomere maintenance;GO:0009408//response to heat;GO:0042026//protein refolding;GO:0006952//defense response;GO:0006986//response to unfolded protein;GO:0006281//DNA repair GO:0044183//protein binding involved in protein folding;GO:0047485//protein N-terminus binding;GO:0031625//ubiquitin protein ligase binding;GO:0051082//unfolded protein binding;GO:0002020//protease binding;GO:0051059//NF-kappaB binding;GO:0005524//ATP binding GO:0016607//nuclear speck;GO:0016323//basolateral plasma membrane;GO:0016235//aggresome;GO:0005829//cytosol;GO:0008180//signalosome;GO:0048471//perinuclear region of cytoplasm;GO:0005783//endoplasmic reticulum;GO:0030529//ribonucleoprotein complex;GO:0016324//apical plasma membrane;GO:0005739//mitochondrion 440 sp|Q96CG8|CTHR1_HUMAN Collagen triple helix repeat-containing protein 1 OS=Homo sapiens GN=CTHRC1 PE=1 SV=1 30428 MRPQGPAASPQRLRGLLLLLLLQLPAPSSASEIPKGKQKAQLRQREVVDLYNGMCLQGPAGVPGRDGSPGANGIPGTPGIPGRDGFKGEKGECLRESFEESWTPNYKQCSWSSLNYGIDLGKIAECTFTKMRSNSALRVLFSGSLRLKCRNACCQRWYFTFNGAECSGPLPIEAIIYLDQGSPEMNSTINIHRTSSVEGLCEGIGAGLVDVAIWVGTCSDYPKGDASTGWNSVSRIIIEELPK 58 11.5 - 7 7 3 3 2.397 1.409 2.581 2 2 2 * - - 2.129 0.630288823 sp|Q96CG8|CTHR1_HUMAN 100 1.00E-109 gi|395739953|ref|XP_003777340.1| PREDICTED: collagen triple helix repeat-containing protein 1 isoform 2 [Pongo abelii] 100 4.00E-130 sp|Q96CG8|CTHR1_HUMAN Collagen triple helix repeat-containing protein 1 OS=Homo sapiens GN=CTHRC1 PE=1 SV=1 100 3.00E-109 G3V141 G3V141_HUMAN Collagen triple helix repeat containing 1, isoform CRA_c OS=Homo sapiens GN=CTHRC1 PE=4 SV=1 - - - - - - - K13649|1|1e-17|90.5|bfo:BRAFLDRAFT_123559|folate receptor GO:0032092//positive regulation of protein binding;GO:0033690//positive regulation of osteoblast proliferation;GO:0090090//negative regulation of canonical Wnt receptor signaling pathway;GO:0090177//establishment of planar polarity involved in neural tube closure;GO:0060071//Wnt receptor signaling pathway, planar cell polarity pathway;GO:0043932//ossification involved in bone remodeling;GO:0060122//inner ear receptor stereocilium organization;GO:0090103//cochlea morphogenesis;GO:0045669//positive regulation of osteoblast differentiation;GO:0016477//cell migration GO:0005109//frizzled binding;GO:0017147//Wnt-protein binding GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005581//collagen 441 sp|Q9UNN8|EPCR_HUMAN Endothelial protein C receptor OS=Homo sapiens GN=PROCR PE=1 SV=1 27909 MLTTLLPILLLSGWAFCSQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGPDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELREFLEDTCVQYVQKHISAENTKGSQTSRSYTSLVLGVLVGSFIIAGVAVGIFLCTGGRRC 57 9.2 - 2 2 2 2 0.895 1.171 0.623 2 2 2 - - - 0.896333333 0.274002433 sp|Q9UNN8|EPCR_HUMAN 100 3.00E-131 gi|34335272|ref|NP_006395.2| endothelial protein C receptor precursor [Homo sapiens] >gi|13626550|sp|Q9UNN8.1|EPCR_HUMAN RecName: Full=Endothelial protein C receptor; AltName: Full=Activated protein C receptor; Short=APC receptor; AltName: Full=Endothelial cell protein C receptor; AltName: CD_antigen=CD201; Flags: Precursor >gi|5499723|gb|AAD43967.1|AF106202_1 endothelial cell protein C receptor precursor [Homo sapiens] >gi|14030741|gb|AAK53045.1|AF375468_1 endothelial protein C receptor [Homo sapiens] >gi|7688207|emb|CAA61450.1| centrocyclin [Homo sapiens] >gi|48146013|emb|CAG33229.1| PROCR [Homo sapiens] >gi|119596630|gb|EAW76224.1| protein C receptor, endothelial (EPCR), isoform CRA_b [Homo sapiens] 100 4.00E-132 sp|Q9UNN8|EPCR_HUMAN Endothelial protein C receptor OS=Homo sapiens GN=PROCR PE=1 SV=1 98.68 2.00E-129 H2R909 H2R909_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000101000 PE=4 SV=1 - - - - - - - K06557|1|5e-132|470|hsa:10544|protein C receptor, endothelial (EPCR) GO:0050819//negative regulation of coagulation;GO:0019882//antigen processing and presentation;GO:0007596//blood coagulation;GO:0006955//immune response GO:0004872//receptor activity;GO:0005515//protein binding GO:0005887//integral to plasma membrane;GO:0005813//centrosome;GO:0042612//MHC class I protein complex 442 sp|P26447|S10A4_HUMAN Protein S100-A4 OS=Homo sapiens GN=S100A4 PE=1 SV=1 15903 MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMSNLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK 721 18.8 - 39 39 2 2 0.419 0.37 0.54 20 20 20 - - * 0.443 0.087504286 sp|P26447|S10A4_HUMAN 100 3.00E-53 gi|171849067|pdb|3C1V|A Chain A, The 1.5 A Crystal Structure Of Ca2+-Bound S100a4 >gi|171849068|pdb|3C1V|B Chain B, The 1.5 A Crystal Structure Of Ca2+-Bound S100a4 >gi|171849069|pdb|3C1V|C Chain C, The 1.5 A Crystal Structure Of Ca2+-Bound S100a4 >gi|171849070|pdb|3C1V|D Chain D, The 1.5 A Crystal Structure Of Ca2+-Bound S100a4 >gi|385251615|pdb|2LNK|A Chain A, Solution Structure Of Ca-Bound S100a4 In Complex With Non-Muscle Myosin Iia >gi|385251616|pdb|2LNK|B Chain B, Solution Structure Of Ca-Bound S100a4 In Complex With Non-Muscle Myosin Iia 100 1.00E-53 sp|P26447|S10A4_HUMAN Protein S100-A4 OS=Homo sapiens GN=S100A4 PE=1 SV=1 100 4.00E-52 G7NUG6 G7NUG6_MACFA Putative uncharacterized protein OS=Macaca fascicularis GN=EGM_01112 PE=4 SV=1 - - - - - - - K10384|1|4e-08|56.6|ecb:100060541|filaggrin!K14734|3|4e-08|56.6|ssc:397265|S100 calcium binding protein G GO:0001837//epithelial to mesenchymal transition;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0050786//RAGE receptor binding;GO:0005509//calcium ion binding;GO:0042802//identical protein binding;GO:0048306//calcium-dependent protein binding GO:0043005//neuron projection;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus 443 tr|Q2TSD0|Q2TSD0_HUMAN Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens PE=2 SV=1 44411 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISTPSADAPMLVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 536 21.2 2 28 28 5 5 0.809 0.716 0.708 19 20 18 * * * 0.744333333 0.056145644 tr|Q2TSD0|Q2TSD0_HUMAN 100 0 gi|54303910|gb|AAV33305.1| aging-associated gene 9 protein [Homo sapiens] 99.4 0 sp|P04406|G3P_HUMAN Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens GN=GAPDH PE=1 SV=3 100 0 Q2TSD0 Q2TSD0_HUMAN Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens PE=2 SV=1 SPBC354.12 501 1.00E-141 COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase G Carbohydrate transport and metabolism ; K00134|1|0.0|688|hsa:2597|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] GO:0051402//neuron apoptotic process;GO:0055114//oxidation-reduction process;GO:0035606//peptidyl-cysteine S-trans-nitrosylation;GO:0050821//protein stabilization;GO:0000226//microtubule cytoskeleton organization;GO:0006096//glycolysis;GO:0006094//gluconeogenesis;GO:0044281//small molecule metabolic process GO:0051287//NAD binding;GO:0008017//microtubule binding;GO:0035605//peptidyl-cysteine S-nitrosylase activity;GO:0004365//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661//NADP binding GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0005811//lipid particle;GO:0016020//membrane;GO:0005634//nucleus 444 tr|A8K8B9|A8K8B9_HUMAN cDNA FLJ77368, highly similar to Homo sapiens protein kinase, cAMP-dependent, catalytic, alpha (PRKACA), transcript variant 2, mRNA OS=Homo sapiens PE=2 SV=1 50312 MASNSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFDFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 77 6.1 1 4 4 2 2 1.4 0.828 1.115 2 3 3 - - - 1.114333333 0.286000583 tr|A8K8B9|A8K8B9_HUMAN 100 0 gi|158258000|dbj|BAF84973.1| unnamed protein product [Homo sapiens] 98.25 0 sp|P17612|KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens GN=PRKACA PE=1 SV=2 100 0 A8K8B9 A8K8B9_HUMAN cDNA FLJ77368, highly similar to Homo sapiens protein kinase, cAMP-dependent, catalytic, alpha (PRKACA), transcript variant 2, mRNA OS=Homo sapiens PE=2 SV=1 SPAC17G8.14c_2 225 9.00E-59 COG0515 Serine/threonine protein kinase RTKL General function prediction only ; Signal transduction mechanisms ; Transcription ; Replication, recombination and repair ; K04345|1|0.0|700|ecb:100064302|protein kinase A [EC:2.7.11.11] GO:0007173//epidermal growth factor receptor signaling pathway;GO:0034351//negative regulation of glial cell apoptotic process;GO:0007190//activation of adenylate cyclase activity;GO:0014070//response to organic cyclic compound;GO:0045921//positive regulation of exocytosis;GO:0021955//central nervous system neuron axonogenesis;GO:0000188//inactivation of MAPK activity;GO:0019433//triglyceride catabolic process;GO:0046777//protein autophosphorylation;GO:2000810//regulation of tight junction assembly;GO:0006874//cellular calcium ion homeostasis;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0050796//regulation of insulin secretion;GO:0002026//regulation of the force of heart contraction;GO:0007194//negative regulation of adenylate cyclase activity;GO:0070555//response to interleukin-1;GO:0045651//positive regulation of macrophage differentiation;GO:0009612//response to mechanical stimulus;GO:0006112//energy reserve metabolic process;GO:0006937//regulation of muscle contraction;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0035408//histone H3-T6 phosphorylation;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0071158//positive regulation of cell cycle arrest;GO:0050729//positive regulation of inflammatory response;GO:0009636//response to toxic substance;GO:0048259//regulation of receptor-mediated endocytosis;GO:0045785//positive regulation of cell adhesion;GO:0051447//negative regulation of meiotic cell cycle;GO:0071377//cellular response to glucagon stimulus;GO:0006833//water transport;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0048240//sperm capacitation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0017148//negative regulation of translation;GO:0050930//induction of positive chemotaxis;GO:0051412//response to corticosterone stimulus;GO:0045931//positive regulation of mitotic cell cycle;GO:0051965//positive regulation of synapse assembly;GO:0090330//regulation of platelet aggregation;GO:0002062//chondrocyte differentiation;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0007611//learning or memory;GO:0046677//response to antibiotic;GO:0071333//cellular response to glucose stimulus;GO:0016071//mRNA metabolic process;GO:0007202//activation of phospholipase C activity;GO:0046827//positive regulation of protein export from nucleus;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0007568//aging;GO:0018105//peptidyl-serine phosphorylation;GO:0045667//regulation of osteoblast differentiation;GO:0055085//transmembrane transport;GO:0045471//response to ethanol;GO:0032355//response to estradiol stimulus;GO:0046325//negative regulation of glucose import;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:2000707//positive regulation of dense core granule biogenesis;GO:0045766//positive regulation of angiogenesis;GO:0030593//neutrophil chemotaxis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0043457//regulation of cellular respiration;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0061136//regulation of proteasomal protein catabolic process;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0000302//response to reactive oxygen species;GO:0006094//gluconeogenesis;GO:0045822//negative regulation of heart contraction;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0001707//mesoderm formation;GO:0034199//activation of protein kinase A activity GO:0019901//protein kinase binding;GO:0004698//calcium-dependent protein kinase C activity;GO:0008270//zinc ion binding;GO:0031625//ubiquitin protein ligase binding;GO:0004691//cAMP-dependent protein kinase activity;GO:0005524//ATP binding;GO:0035403//histone kinase activity (H3-T6 specific) GO:0043025//neuronal cell body;GO:0005952//cAMP-dependent protein kinase complex;GO:0031966//mitochondrial membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005654//nucleoplasm;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0005813//centrosome;GO:0031594//neuromuscular junction;GO:0048471//perinuclear region of cytoplasm;GO:0030425//dendrite;GO:0001750//photoreceptor outer segment 445 tr|A0A087WYS1|A0A087WYS1_HUMAN UTP--glucose-1-phosphate uridylyltransferase OS=Homo sapiens GN=UGP2 PE=1 SV=1 69879 MRIFVEDLSKAMSQDGASQFQEVIRQELELSVKKELEKILTTASSHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIKARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRCEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGLNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH 203 18.5 3 18 18 8 8 0.812 1.02 0.888 6 6 6 - - - 0.906666667 0.105248911 tr|A0A087WYS1|A0A087WYS1_HUMAN 100 3.00E-24 gi|149044769|gb|EDL97955.1| UDP-glucose pyrophosphorylase 2, isoform CRA_a [Rattus norvegicus] 99.41 0 sp|Q16851|UGPA_HUMAN UTP--glucose-1-phosphate uridylyltransferase OS=Homo sapiens GN=UGP2 PE=1 SV=5 100 0 D6W5E6 D6W5E6_HUMAN UDP-glucose pyrophosphorylase 2, isoform CRA_b OS=Homo sapiens GN=UGP2 PE=4 SV=1 SPCC1322.04 534 2.00E-151 COG4284 UDP-glucose pyrophosphorylase G Carbohydrate transport and metabolism ; K00963|1|0.0|962|rno:289827|UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] GO:0006805//xenobiotic metabolic process;GO:0019255//glucose 1-phosphate metabolic process;GO:0006011//UDP-glucose metabolic process;GO:0016310//phosphorylation;GO:0006006//glucose metabolic process;GO:0006065//UDP-glucuronate biosynthetic process;GO:0005978//glycogen biosynthetic process GO:0003983//UTP:glucose-1-phosphate uridylyltransferase activity;GO:0032557//pyrimidine ribonucleotide binding;GO:0046872//metal ion binding;GO:0005536//glucose binding;GO:0005515//protein binding GO:0005829//cytosol 446 sp|Q86UD1|OAF_HUMAN Out at first protein homolog OS=Homo sapiens GN=OAF PE=2 SV=1 35194 MRLPGVPLARPALLLLLPLLAPLLGTGAPAELRVRVRLPDGQVTEESLQADSDADSISLELRKPDGTLVSFTADFKKDVKVFRALILGELEKGQSQFQALCFVTQLQHNEIIPSEAMAKLRQKNPRAVRQAEEVRGLEHLHMDVAVNFSQGALLSPHLHNVCAEAVDAIYTRQEDVRFWLEQGVDSSVFEALPKASEQAELPRCRQVGDHGKPCVCRYGLSLAWYPCMLKYCHSRDRPTPYKCGIRSCQKSYSFDFYVPQRQLCLWDEDPYPG 97 14.7 - 6 6 3 3 1.409 1.023 1.478 4 4 4 * - * 1.303333333 0.245214872 sp|Q86UD1|OAF_HUMAN 100 1.00E-140 gi|30425438|ref|NP_848602.1| out at first protein homolog precursor [Homo sapiens] >gi|74727479|sp|Q86UD1.1|OAF_HUMAN RecName: Full=Out at first protein homolog; AltName: Full=HCV NS5A-transactivated protein 13 target protein 2; Flags: Precursor >gi|28838376|gb|AAH47726.1| OAF homolog (Drosophila) [Homo sapiens] >gi|38505473|gb|AAR23238.1| NS5ATP13TP2 [Homo sapiens] 100 1.00E-141 sp|Q86UD1|OAF_HUMAN Out at first protein homolog OS=Homo sapiens GN=OAF PE=2 SV=1 100 8.00E-90 E9PJ29 E9PJ29_HUMAN Out at first protein homolog OS=Homo sapiens GN=OAF PE=4 SV=1 - - - - - - - - - - 447 tr|A8K3S1|A8K3S1_HUMAN Glucosamine-6-phosphate isomerase OS=Homo sapiens PE=2 SV=1 40738 MKLIILEHYPQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDAFEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCDEDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD 137 23.9 1 13 13 6 6 0.962 0.913 1.053 4 4 4 - - - 0.976 0.071042241 tr|A8K3S1|A8K3S1_HUMAN 100 8.00E-163 gi|158254808|dbj|BAF83375.1| unnamed protein product [Homo sapiens] 99.65 4.00E-163 sp|P46926|GNPI1_HUMAN Glucosamine-6-phosphate isomerase 1 OS=Homo sapiens GN=GNPDA1 PE=1 SV=1 100 3.00E-162 A8K3S1 A8K3S1_HUMAN cDNA FLJ76269, highly similar to Homo sapiens glucosamine-6-phosphate deaminase 1 (GNPDA1), mRNA OS=Homo sapiens PE=2 SV=1 PM0875 343 2.00E-94 COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase G Carbohydrate transport and metabolism ; K02564|1|4e-163|573|hsa:10007|glucosamine-6-phosphate deaminase [EC:3.5.99.6] GO:0007340//acrosome reaction;GO:0006002//fructose 6-phosphate metabolic process;GO:0046370//fructose biosynthetic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0006043//glucosamine catabolic process;GO:0006091//generation of precursor metabolites and energy GO:0004342//glucosamine-6-phosphate deaminase activity;GO:0016787//hydrolase activity GO:0005737//cytoplasm 448 sp|P27348|1433T_HUMAN 14-3-3 protein theta OS=Homo sapiens GN=YWHAQ PE=1 SV=1 34116 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN 445 24.9 - 31 13 5 3 0.737 0.487 0.582 11 11 11 * * * 0.602 0.126194295 sp|P27348|1433T_HUMAN 100 1.00E-131 gi|5803227|ref|NP_006817.1| 14-3-3 protein theta [Homo sapiens] >gi|118151330|ref|NP_001071595.1| 14-3-3 protein theta [Bos taurus] >gi|112690|sp|P27348.1|1433T_HUMAN RecName: Full=14-3-3 protein theta; AltName: Full=14-3-3 protein T-cell; AltName: Full=14-3-3 protein tau; AltName: Full=Protein HS1 >gi|68565141|sp|Q5RFJ2.2|1433T_PONAB RecName: Full=14-3-3 protein theta >gi|82592596|sp|Q3SZI4.1|1433T_BOVIN RecName: Full=14-3-3 protein theta >gi|23222|emb|CAA39840.1| 14.3.3 protein [Homo sapiens] >gi|32464|emb|CAA40622.1| HS1 [Homo sapiens] >gi|34785143|gb|AAH56867.1| Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide [Homo sapiens] >gi|55930909|gb|AAH50601.1| Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide [Homo sapiens] >gi|62205258|gb|AAH93019.1| Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide [Homo sapiens] >gi|74354028|gb|AAI02841.1| Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide [Bos taurus] >gi|119621382|gb|EAX00977.1| tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide, isoform CRA_a [Homo sapiens] >gi|119621384|gb|EAX00979.1| tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide, isoform CRA_a [Homo sapiens] >gi|152941256|gb|ABS45065.1| tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide [Bos taurus] >gi|154426168|gb|AAI51415.1| Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide [Bos taurus] >gi|296482326|tpg|DAA24441.1| TPA: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide [Bos taurus] >gi|351704793|gb|EHB07712.1| 14-3-3 protein theta [Heterocephalus glaber] >gi|444731699|gb|ELW72048.1| 14-3-3 protein theta [Tupaia chinensis] 100 1.00E-132 sp|P27348|1433T_HUMAN 14-3-3 protein theta OS=Homo sapiens GN=YWHAQ PE=1 SV=1 100 4.00E-131 G1RT54 G1RT54_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=ENSG00000134308 PE=3 SV=1 SPAC8E11.02c 306 3.00E-83 COG5040 14-3-3 family protein T Signal transduction mechanisms ; K06630|1|4e-134|477|ptr:470302|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein GO:0055114//oxidation-reduction process;GO:0007264//small GTPase mediated signal transduction;GO:0006605//protein targeting;GO:0045892//negative regulation of transcription, DNA-dependent GO:0047485//protein N-terminus binding;GO:0004497//monooxygenase activity;GO:0071889//14-3-3 protein binding;GO:0019904//protein domain specific binding GO:0043234//protein complex;GO:0005730//nucleolus;GO:0005813//centrosome 449 tr|B7Z6C2|B7Z6C2_HUMAN cDNA FLJ50663, highly similar to Phosphoglucomutase-1 (EC 5.4.2.2) OS=Homo sapiens PE=2 SV=1 75612 MSDFEEWISGTYRKMEEGPLPLLTFATAPYHDQKPGTSGLRKKTYYFEEKPCYLENFIQSIFFSIDLKDRQGSSLVVGGDGRYFNKSAIETIVQMAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAVCPDLKVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRSIFDFSALKELLSGPNRLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVASATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHVREKDGLWAVLAWLSILATRKQSVEDILKDHWQKHGRNFFTRYDYEEVEAEGANKMMKDLEALMFDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISRNQGLRLIFTDGSRIVFRLSGTGSAGATIRLYIDSYEKDVAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT 81 9.1 2 8 8 5 5 0.586 1.6 0.618 2 2 2 - - - 0.934666667 0.576417673 tr|B7Z6C2|B7Z6C2_HUMAN 100 0 gi|221043062|dbj|BAH13208.1| unnamed protein product [Homo sapiens] 92.69 0 sp|P36871|PGM1_HUMAN Phosphoglucomutase-1 OS=Homo sapiens GN=PGM1 PE=1 SV=3 100 0 B7Z6C2 B7Z6C2_HUMAN cDNA FLJ50663, highly similar to Phosphoglucomutase-1 (EC 5.4.2.2) OS=Homo sapiens PE=2 SV=1 SMc03925 606 4.00E-173 COG0033 Phosphoglucomutase G Carbohydrate transport and metabolism ; K01835|1|0.0|1142|hsa:5236|phosphoglucomutase [EC:5.4.2.2] GO:0005980//glycogen catabolic process;GO:0019388//galactose catabolic process;GO:0005992//trehalose biosynthetic process;GO:0006006//glucose metabolic process;GO:0044281//small molecule metabolic process;GO:0005978//glycogen biosynthetic process GO:0000287//magnesium ion binding;GO:0004614//phosphoglucomutase activity GO:0005829//cytosol;GO:0015629//actin cytoskeleton 450 sp|Q9BUD6|SPON2_HUMAN Spondin-2 OS=Homo sapiens GN=SPON2 PE=1 SV=3 39075 MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARALAKYSITFTGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSVHEVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQAALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVTLVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAECVPDNCV 533 20.5 - 48 48 7 7 1.422 1.34 1.046 23 23 23 * * - 1.269333333 0.197710226 sp|Q9BUD6|SPON2_HUMAN 100 2.00E-175 gi|313104285|sp|Q9BUD6.3|SPON2_HUMAN RecName: Full=Spondin-2; AltName: Full=Differentially expressed in cancerous and non-cancerous lung cells 1; Short=DIL-1; AltName: Full=Mindin; Flags: Precursor 100 2.00E-176 sp|Q9BUD6|SPON2_HUMAN Spondin-2 OS=Homo sapiens GN=SPON2 PE=1 SV=3 100 2.00E-38 D6RB12 D6RB12_HUMAN Spondin-2 (Fragment) OS=Homo sapiens GN=SPON2 PE=4 SV=1 - - - - - - - - GO:0045087//innate immune response;GO:0007411//axon guidance;GO:0007155//cell adhesion GO:0046872//metal ion binding;GO:0005102//receptor binding GO:0005578//proteinaceous extracellular matrix 451 tr|A8KAM8|A8KAM8_HUMAN Tyrosine-protein kinase receptor OS=Homo sapiens PE=2 SV=1 136787 MRLPGAMPALALKGELLLLSLLLLLEPQISQGLVVTPPGPELVLNVSSTFVLTCSGSAPVVWERMSQEPPQEMAKAQDGTFSSVLTLTNLTGLDTGEYFCTHNDSRGLETDERKRLYIFVPDPTVGFLPNDAEELFIFLTEITEITIPCRVTDPQLVVTLHEKKGDVALPVPYDHQRGFSGIFEDRSYICKTTIGDREVDSDAYYVYRLQVSSINVSVNAVQTVVRQGENITLMCIVIGNEVVNFEWTYPRKESGRLVEPVTDSLLDMPYHIRSILHIPSAELEDSGTYTCNVTESVNDHQDEKAINITVVESGYVRLLGEVGTLQFAELHRSRTLQVVFEAYPPPTVLWFKDNRTLGDSSAGEIALSTRNVSETRYVSELTLVRVKVAEAGHYTMRAFHEDAEVQLSFQLQINVPVRVLELSESHPDSGEQTVRCRGRGMPQPNIIWSACRDLKRCPRELPPTLLGNSSEEESQLETNVTYWEEEQEFEVVSTLRLQHVDRPLSVRCTLRNAVGQDTQEVIVVPHSLPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQHHSDKRRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIESPNYMAPYDNYVPSAPERTCRATLINESPVLSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGEGYKKKYQQVDEEFLRSDHPAILRSQARLPGFHGLRSPLDTSSVLYTAVQPNEGDNDYIIPLPDPKPEVADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQDEPEPEPQLELQVEPEPELEQLPDSGCPAPRAEAEDSFL 143 3.3 1 5 5 3 3 1.334 1.449 1.139 4 4 4 - * - 1.307333333 0.156710987 tr|A8KAM8|A8KAM8_HUMAN 100 0 gi|158259647|dbj|BAF85782.1| unnamed protein product [Homo sapiens] 99.82 0 sp|P09619|PGFRB_HUMAN Platelet-derived growth factor receptor beta OS=Homo sapiens GN=PDGFRB PE=1 SV=1 100 0 A8KAM8 A8KAM8_HUMAN cDNA FLJ76012, highly similar to Homo sapiens platelet-derived growth factor receptor, betapolypeptide (PDGFRB), mRNA OS=Homo sapiens PE=2 SV=1 YAR019c 72.4 5.00E-12 COG0515 Serine/threonine protein kinase RTKL General function prediction only ; Signal transduction mechanisms ; Transcription ; Replication, recombination and repair ; K05089|1|0.0|2009|hsa:5159|platelet-derived growth factor receptor beta [EC:2.7.10.1] GO:0032956//regulation of actin cytoskeleton organization;GO:0001894//tissue homeostasis;GO:0001701//in utero embryonic development;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0060981//cell migration involved in coronary angiogenesis;GO:0035909//aorta morphogenesis;GO:0048745//smooth muscle tissue development;GO:0061298//retina vasculature development in camera-type eye;GO:2000573//positive regulation of DNA biosynthetic process;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0043406//positive regulation of MAP kinase activity;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0010863//positive regulation of phospholipase C activity;GO:0035441//cell migration involved in vasculogenesis;GO:0014911//positive regulation of smooth muscle cell migration;GO:0072277//metanephric glomerular capillary formation;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0072262//metanephric glomerular mesangial cell proliferation involved in metanephros development;GO:0046488//phosphatidylinositol metabolic process;GO:0050921//positive regulation of chemotaxis;GO:0046777//protein autophosphorylation;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0038091//positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway;GO:0055003//cardiac myofibril assembly;GO:0045840//positive regulation of mitosis;GO:0071670//smooth muscle cell chemotaxis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0048705//skeletal system morphogenesis;GO:0030325//adrenal gland development;GO:0090280//positive regulation of calcium ion import;GO:0014068//positive regulation of phosphatidylinositol 3-kinase cascade;GO:0035793//positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway GO:0005019//platelet-derived growth factor beta-receptor activity;GO:0048407//platelet-derived growth factor binding;GO:0038085//vascular endothelial growth factor binding;GO:0005161//platelet-derived growth factor receptor binding;GO:0005524//ATP binding;GO:0004992//platelet activating factor receptor activity;GO:0005021//vascular endothelial growth factor-activated receptor activity GO:0016324//apical plasma membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0043202//lysosomal lumen;GO:0005887//integral to plasma membrane;GO:0005634//nucleus 452 tr|A5PLK9|A5PLK9_HUMAN Metalloendopeptidase OS=Homo sapiens GN=BMP1 PE=2 SV=1 131159 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDEEDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCINTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKNECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK 103 4.4 1 12 12 4 4 2.089 1.216 1.009 4 4 4 * - - 1.438 0.573204152 tr|A5PLK9|A5PLK9_HUMAN 100 0 gi|148745745|gb|AAI42954.1| Bone morphogenetic protein 1 [Homo sapiens] 99.8 0 sp|P13497|BMP1_HUMAN Bone morphogenetic protein 1 OS=Homo sapiens GN=BMP1 PE=1 SV=2 100 0 A5PLK9 A5PLK9_HUMAN Bone morphogenetic protein 1 OS=Homo sapiens GN=BMP1 PE=2 SV=1 - - - - - - - K05502|1|0.0|1958|pon:100453093|bone morphogenetic protein 1 [EC:3.4.24.19] GO:0006629//lipid metabolic process;GO:0001503//ossification;GO:0061036//positive regulation of cartilage development;GO:0042157//lipoprotein metabolic process;GO:0006508//proteolysis;GO:0030154//cell differentiation;GO:0001502//cartilage condensation;GO:0044281//small molecule metabolic process;GO:0030198//extracellular matrix organization GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0005125//cytokine activity;GO:0004222//metalloendopeptidase activity;GO:0008083//growth factor activity GO:0031988//membrane-bounded vesicle;GO:0005581//collagen;GO:0005615//extracellular space 453 tr|Q5VY30|Q5VY30_HUMAN Retinol binding protein 4, plasma, isoform CRA_b OS=Homo sapiens GN=RBP4 PE=1 SV=2 26952 MNYSKIPAQVDLRRQTERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYCDGRSERNLL 46 5 1 3 3 1 1 0.89 0.51 0.911 2 2 2 - - - 0.770333333 0.225699653 tr|Q5VY30|Q5VY30_HUMAN 100 3.00E-35 gi|5419892|emb|CAB46489.1| unnamed protein product [Homo sapiens] 98.92 4.00E-107 sp|P61641|RET4_PANTR Retinol-binding protein 4 OS=Pan troglodytes GN=RBP4 PE=3 SV=1 100 2.00E-115 A6NCP9 A6NCP9_HUMAN Plasma retinol-binding protein(1-181) OS=Homo sapiens GN=RBP4 PE=3 SV=2 - - - - - - - - GO:0006094//gluconeogenesis;GO:0030324//lung development;GO:0060347//heart trabecula formation;GO:0050908//detection of light stimulus involved in visual perception;GO:0032868//response to insulin stimulus;GO:0048562//embryonic organ morphogenesis;GO:0045471//response to ethanol;GO:0032526//response to retinoic acid;GO:0034633//retinol transport;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0030277//maintenance of gastrointestinal epithelium;GO:0048706//embryonic skeletal system development;GO:0042572//retinol metabolic process;GO:0060068//vagina development;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0042574//retinal metabolic process;GO:0060157//urinary bladder development;GO:0051024//positive regulation of immunoglobulin secretion;GO:0048807//female genitalia morphogenesis;GO:0032024//positive regulation of insulin secretion;GO:0042593//glucose homeostasis;GO:0060065//uterus development GO:0034632//retinol transporter activity;GO:0005515//protein binding;GO:0016918//retinal binding;GO:0019841//retinol binding GO:0005615//extracellular space 454 tr|B4DGD0|B4DGD0_HUMAN cDNA FLJ50491, highly similar to Amyloid beta A4 protein (APP) (ABPP)(Alzheimer disease amyloid protein) (Cerebral vascularamyloid peptide) (CVAP) (Protease nexin-II) (PN-II)(APPI) (PreA4) OS=Homo sapiens PE=2 SV=1 93475 MLPGLALLLLAAWTARALEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDESEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN 492 10.9 2 24 24 6 6 1.541 1.473 1.158 15 16 14 * * - 1.390666667 0.204343665 tr|B4DGD0|B4DGD0_HUMAN 100 4.00E-76 gi|194382392|dbj|BAG58951.1| unnamed protein product [Homo sapiens] 100 2.00E-16 sp|Q28280|A4_CANFA Amyloid beta A4 protein (Fragment) OS=Canis familiaris GN=APP PE=3 SV=1 100 1.00E-75 E9PEV0 E9PEV0_HUMAN C99 OS=Homo sapiens GN=APP PE=4 SV=1 - - - - - - - K04520|1|0.0|941|hsa:351|amyloid beta (A4) protein GO:0010466//negative regulation of peptidase activity;GO:0045665//negative regulation of neuron differentiation;GO:0050885//neuromuscular process controlling balance;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0050803//regulation of synapse structure and activity;GO:0016358//dendrite development;GO:0000085//G2 phase of mitotic cell cycle;GO:0048669//collateral sprouting in absence of injury;GO:0040014//regulation of multicellular organism growth;GO:0030900//forebrain development;GO:0008203//cholesterol metabolic process;GO:0030168//platelet activation;GO:0001967//suckling behavior;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0008542//visual learning;GO:0016199//axon midline choice point recognition;GO:0006979//response to oxidative stress;GO:0051402//neuron apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0045087//innate immune response;GO:0007219//Notch signaling pathway;GO:0002576//platelet degranulation;GO:0008344//adult locomotory behavior;GO:0006897//endocytosis;GO:0043393//regulation of protein binding;GO:0007617//mating behavior;GO:0030198//extracellular matrix organization;GO:0045931//positive regulation of mitotic cell cycle;GO:0006417//regulation of translation;GO:0006878//cellular copper ion homeostasis;GO:0007155//cell adhesion;GO:0016322//neuron remodeling;GO:0051563//smooth endoplasmic reticulum calcium ion homeostasis;GO:0006378//mRNA polyadenylation;GO:0051124//synaptic growth at neuromuscular junction;GO:0008088//axon cargo transport GO:0008201//heparin binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0033130//acetylcholine receptor binding;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0051425//PTB domain binding;GO:0046914//transition metal ion binding GO:0009986//cell surface;GO:0043198//dendritic shaft;GO:0031594//neuromuscular junction;GO:0005829//cytosol;GO:0035253//ciliary rootlet;GO:0030424//axon;GO:0051233//spindle midzone;GO:0005887//integral to plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005794//Golgi apparatus;GO:0031093//platelet alpha granule lumen;GO:0045177//apical part of cell;GO:0005905//coated pit;GO:0043197//dendritic spine;GO:0005576//extracellular region 455 tr|B2ZZ86|B2ZZ86_HUMAN Collagen type V alpha 1 OS=Homo sapiens GN=COL5A1 PE=2 SV=1 214278 MDVHTRWKARSALRPGAPLLPPLLLLLLWAPPPSRAAQPADLLKVLDFHNLPDGITKTTGFCATRRSSKGPDVAYRVTKDAQLSAPTKQLYPASAFPEDFSILTTVKAKKGSQAFLVSIYNEQGIQQIGLELGRSPVFLYEDHTGKPGPEDYPLFRGINLSDGKWHRIALSVHKKNVTLILDCKKKTTKFLDRSDHPMIDINGIIVFGTRILDEEVFEGDIQQLLFVSDHRAAYDYCEHYSPDCDTAVPDTPQSQDPNPDEYYTEGDGEGETYYYEYPYYEDPEDLGKEPTPSKKPVEAAKETTEVPEELTPTPTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGSDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASRTRRNIDASQLLDDGNGENYVDYADGMEEIFGSLNSLKLEIEQMKRPLGTQQNPARTCKDLQLCHPDFPDGEYWVDPNQGCSRDSFKVYCNFTAGGSTCVFPDKKSEGARITSWPKENPGSWFSEFKRGKLLSYVDAEGNPVGVVQMTFLRLLSASAHQNVTYHCYQSVAWQDAATGSYDKALRFLGSNDEEMSYDNNPYIRALVDGCATKKGYQKTVLEIDTPKVEQVPIVDIMFNDFGEASQKFGFEVGPACFMG 469 5.3 1 24 17 7 6 0.897 0.809 0.903 9 9 8 - - - 0.869666667 0.052624456 tr|B2ZZ86|B2ZZ86_HUMAN 100 5.00E-13 gi|355567351|gb|EHH23692.1| hypothetical protein EGK_07220, partial [Macaca mulatta] >gi|355752945|gb|EHH56991.1| hypothetical protein EGM_06539, partial [Macaca fascicularis] 100 1.00E-13 sp|P20908|CO5A1_HUMAN Collagen alpha-1(V) chain OS=Homo sapiens GN=COL5A1 PE=1 SV=3 100 3.00E-180 Q96HC0 Q96HC0_HUMAN COL5A1 protein OS=Homo sapiens PE=2 SV=3 - - - - - - - K06236|1|0.0|743|hsa:1289|collagen, type I/II/III/V/XI, alpha GO:0043206//extracellular fibril organization;GO:0035313//wound healing, spreading of epidermal cells;GO:0048592//eye morphogenesis;GO:0043588//skin development;GO:0007155//cell adhesion;GO:0030199//collagen fibril organization;GO:0032964//collagen biosynthetic process;GO:0045112//integrin biosynthetic process GO:0043394//proteoglycan binding;GO:0048407//platelet-derived growth factor binding;GO:0008201//heparin binding GO:0005588//collagen type V 456 tr|B4DZY7|B4DZY7_HUMAN cDNA FLJ57022, highly similar to Growth-arrest-specific protein 6 OS=Homo sapiens PE=2 SV=1 67175 MGNFFCLCKAGWGGRLCDKDVNECSQENGGCLQICHNKPGSFHCSCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQGRCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPCVPFSVAKSVKSLYLGRMFSGTPVIRLRFKRLQPTRLVAEFDFRTFDPEGILLFAGGHQDSTWIVLALRAGRLELQLRYNGVGRVTSSGPVINHGMWQTISVEELARNLVIKVNRDAVMKIAVAGDLFQPERGLYHLNLTVGGIPFHEKDLVQPINPRLDGCMRSWNWLNGEDTTIQETVKVNTRMQCFSVTERGSFYPGSGFAFYSLDYMRTPLDVGTESTWEVEVVAHIRPAADTGVLFALWAPDLRAVPLSVALVDYHSTKKLKKQLVVLAVEHTALALMEIKVCDGQEHVVTVSLRDGEATLEVDGTRGQSEVSAAQLQERLAVLERHLRSPVLTFAGGLPDVPVTSAPVTAFYRGCMTLEVNRRLLDLDEAAYKHSDITAHSCPPVEPAAA 357 17.2 1 20 20 7 7 1.499 1.691 2.395 11 11 11 - - * 1.861666667 0.471751347 tr|B4DZY7|B4DZY7_HUMAN 100 0 gi|194381760|dbj|BAG64249.1| unnamed protein product [Homo sapiens] 92.65 0 sp|Q14393|GAS6_HUMAN Growth arrest-specific protein 6 OS=Homo sapiens GN=GAS6 PE=1 SV=2 100 0 E9PBL7 E9PBL7_HUMAN Growth arrest-specific protein 6 OS=Homo sapiens GN=GAS6 PE=4 SV=1 - - - - - - - K05464|1|0.0|1096|hsa:2621|growth arrest-specific 6 GO:0048146//positive regulation of fibroblast proliferation;GO:0040008//regulation of growth;GO:0009267//cellular response to starvation;GO:0035754//B cell chemotaxis;GO:0043687//post-translational protein modification;GO:0031589//cell-substrate adhesion;GO:0019064//viral entry into host cell via membrane fusion with the plasma membrane;GO:0019079//viral genome replication;GO:0050711//negative regulation of interleukin-1 secretion;GO:0035690//cellular response to drug;GO:0032008//positive regulation of TOR signaling cascade;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0071363//cellular response to growth factor stimulus;GO:0007050//cell cycle arrest;GO:0032720//negative regulation of tumor necrosis factor production;GO:0070168//negative regulation of biomineral tissue development;GO:2000533//negative regulation of renal albumin absorption;GO:0048771//tissue remodeling;GO:1900165//negative regulation of interleukin-6 secretion;GO:0002576//platelet degranulation;GO:0097028//dendritic cell differentiation;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0035457//cellular response to interferon-alpha;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0001764//neuron migration;GO:0032715//negative regulation of interleukin-6 production;GO:0071307//cellular response to vitamin K;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0071333//cellular response to glucose stimulus;GO:0050766//positive regulation of phagocytosis;GO:0046813//virion attachment, binding of host cell surface receptor;GO:0010628//positive regulation of gene expression;GO:0003104//positive regulation of glomerular filtration;GO:0042246//tissue regeneration;GO:0046827//positive regulation of protein export from nucleus;GO:0033159//negative regulation of protein import into nucleus, translocation;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006508//proteolysis;GO:0043277//apoptotic cell clearance;GO:2000669//negative regulation of dendritic cell apoptotic process;GO:0072661//protein targeting to plasma membrane;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:2000510//positive regulation of dendritic cell chemotaxis;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0032689//negative regulation of interferon-gamma production;GO:0032148//activation of protein kinase B activity;GO:1900142//negative regulation of oligodendrocyte apoptotic process;GO:0010934//macrophage cytokine production;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0085029//extracellular matrix assembly;GO:0032825//positive regulation of natural killer cell differentiation;GO:0070527//platelet aggregation;GO:0031100//organ regeneration;GO:2000270//negative regulation of fibroblast apoptotic process;GO:0045892//negative regulation of transcription, DNA-dependent;GO:0051897//positive regulation of protein kinase B signaling cascade;GO:0097241//hematopoietic stem cell migration to bone marrow GO:0008083//growth factor activity;GO:0030296//protein tyrosine kinase activator activity;GO:0060090//binding, bridging;GO:0030971//receptor tyrosine kinase binding;GO:0005245//voltage-gated calcium channel activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0005509//calcium ion binding;GO:0048018//receptor agonist activity;GO:0001786//phosphatidylserine binding GO:0005796//Golgi lumen;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen 457 sp|Q9HB40|RISC_HUMAN Retinoid-inducible serine carboxypeptidase OS=Homo sapiens GN=SCPEP1 PE=1 SV=1 60513 MELALRRSPVPRWLLLLPLLLGLNAGAVIDWPTEEGKEVWDYVTVRKDAYMFWWLYYATNSCKNFSELPLVMWLQGGPGGSSTGFGNFEEIGPLDSDLKPRKTTWLQAASLLFVDNPVGTGFSYVNGSGAYAKDLAMVASDMMVLLKTFFSCHKEFQTVPFYIFSESYGGKMAAGIGLELYKAIQRGTIKCNFAGVALGDSWISPVDSVLSWGPYLYSMSLLEDKGLAEVSKVAEQVLNAVNKGLYREATELWGKAEMIIEQNTDGVNFYNILTKSTPTSTMESSLEFTQSHLVCLCQRHVRHLQRDALSQLMNGPIRKKLKIIPEDQSWGGQATNVFVNMEEDFMKPVISIVDELLEAGINVTVYNGQLDLIVDTMGQEAWVRKLKWPELPKFSQLKWKALYSDPKSLETSAFVKSYKNLAFYWILKAGHMVPSDQGDMALKMMRLVTQQE 92 7.7 - 5 5 3 3 1.756 0.786 1.744 2 2 2 - - - 1.428666667 0.556598 sp|Q9HB40|RISC_HUMAN 100 0 gi|11640576|gb|AAG39285.1|AF113214_1 MSTP034 [Homo sapiens] 100 0 sp|Q9HB40|RISC_HUMAN Retinoid-inducible serine carboxypeptidase OS=Homo sapiens GN=SCPEP1 PE=1 SV=1 99.75 0 B4DP22 B4DP22_HUMAN cDNA FLJ55993, highly similar to Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) OS=Homo sapiens PE=2 SV=1 SPAC19G12.10c_2 127 4.00E-29 COG2939 Carboxypeptidase C (cathepsin A) E Amino acid transport and metabolism ; K09646|1|0.0|862|hsa:59342|serine carboxypeptidase 1 [EC:3.4.16.-] GO:0042573//retinoic acid metabolic process;GO:0006508//proteolysis GO:0004185//serine-type carboxypeptidase activity GO:0005576//extracellular region;GO:0005829//cytosol 458 sp|P35754|GLRX1_HUMAN Glutaredoxin-1 OS=Homo sapiens GN=GLRX PE=1 SV=2 >tr|A0A024RAM2|A0A024RAM2_HUMAN Glutaredoxin (Thioltransferase), isoform CRA_c OS=Homo sapiens GN=GLRX PE=4 SV=1 14183 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ 132 23.6 - 10 10 3 3 0.629 0.596 0.383 6 6 6 - * * 0.536 0.133525279 sp|P35754|GLRX1_HUMAN 100 2.00E-55 gi|4504025|ref|NP_002055.1| glutaredoxin-1 [Homo sapiens] >gi|169646776|ref|NP_001112362.1| glutaredoxin-1 [Homo sapiens] >gi|304766562|ref|NP_001182153.1| glutaredoxin-1 [Pan troglodytes] >gi|343887374|ref|NP_001230587.1| glutaredoxin-1 [Homo sapiens] >gi|343887376|ref|NP_001230588.1| glutaredoxin-1 [Homo sapiens] >gi|1346143|sp|P35754.2|GLRX1_HUMAN RecName: Full=Glutaredoxin-1; AltName: Full=Thioltransferase-1; Short=TTase-1 >gi|157831548|pdb|1JHB|A Chain A, Human Glutaredoxin In Fully Reduced Form, Nmr, 20 Structures >gi|5442446|gb|AAD43353.1|AF162769_1 thioltransferase [Homo sapiens] >gi|531405|emb|CAA54094.1| glutaredoxin [Homo sapiens] >gi|3603310|gb|AAC35798.1| glutaredoxin [Homo sapiens] >gi|4063519|gb|AAC98318.1| glutaredoxin [Homo sapiens] >gi|13529038|gb|AAH05304.1| GLRX protein [Homo sapiens] >gi|15012115|gb|AAH10965.1| GLRX protein [Homo sapiens] >gi|30582217|gb|AAP35335.1| glutaredoxin (thioltransferase) [Homo sapiens] >gi|47496571|emb|CAG29308.1| GLRX [Homo sapiens] >gi|49457326|emb|CAG46962.1| GLRX [Homo sapiens] >gi|63055291|gb|AAY29058.1| glutaredoxin (thioltransferase) [Homo sapiens] >gi|76779257|gb|AAI06076.1| GLRX protein [Homo sapiens] >gi|119616462|gb|EAW96056.1| glutaredoxin (thioltransferase), isoform CRA_c [Homo sapiens] >gi|119616463|gb|EAW96057.1| glutaredoxin (thioltransferase), isoform CRA_c [Homo sapiens] >gi|1093459|prf||2104198A glutaredoxin >gi|1584612|prf||2123294A thioltransferase 100 3.00E-56 sp|P35754|GLRX1_HUMAN Glutaredoxin-1 OS=Homo sapiens GN=GLRX PE=1 SV=2 100 1.00E-54 H2PG48 H2PG48_PONAB Uncharacterized protein OS=Pongo abelii GN=LOC100449892 PE=4 SV=1 SPAC4F10.20 73.2 1.00E-13 COG0695 Glutaredoxin and related proteins O Posttranslational modification, protein turnover, chaperones ; K03676|1|3e-56|216|pon:100436888|glutaredoxin 3 GO:0045454//cell redox homeostasis;GO:0006810//transport;GO:0015949//nucleobase-containing small molecule interconversion;GO:0022900//electron transport chain GO:0009055//electron carrier activity;GO:0047485//protein N-terminus binding;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0019153//protein-disulfide reductase (glutathione) activity;GO:0015035//protein disulfide oxidoreductase activity GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion 459 tr|B4E3A8|B4E3A8_HUMAN cDNA FLJ53963, highly similar to Leukocyte elastase inhibitor OS=Homo sapiens PE=2 SV=1 47901 MAMVFLGTRGNTAAQLSKTFHFNTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 112 10 1 4 2 3 2 1.043 0.689 1.037 2 2 2 - - - 0.923 0.202672149 tr|B4E3A8|B4E3A8_HUMAN 100 0 gi|194388072|dbj|BAG65420.1| unnamed protein product [Homo sapiens] 100 0 sp|P30740|ILEU_HUMAN Leukocyte elastase inhibitor OS=Homo sapiens GN=SERPINB1 PE=1 SV=1 100 0 B4E3A8 B4E3A8_HUMAN Leukocyte elastase inhibitor OS=Homo sapiens GN=SERPINB1 PE=2 SV=1 MA3388 198 1.00E-50 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K13963|1|0.0|672|hsa:1992|serpin B GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis GO:0004867//serine-type endopeptidase inhibitor activity GO:0005737//cytoplasm;GO:0005615//extracellular space 460 tr|C9JIF9|C9JIF9_HUMAN Acylamino-acid-releasing enzyme OS=Homo sapiens GN=APEH PE=1 SV=1 91527 MERQVLLSEPEEAAALYRGLSRQPALSAACLGPEVTTQYGGQYRTVHTEWTQRDLERMENIRFCRQYLVFHDGDSVVFAGPAGNSVETRGELLSRESPSGTMKAVLRKAGGTGPGEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTKALDVSASDDEIARLKKPDQAIKGDQFVFYEDWGENMVSKSIPVLCVLDVESGNISVLEGVPENVSPGQAFWAPGDAGVVFVGWWHEPFRLGIRFCTNRRSALYYVDLIGGKCELLSDDSLAVSSPRLSPDQCRIVYLQYPSLIPHHQCSQLCLYDWYTKVTSVVVDVVPRQLGENFSGIYCSLLPLGCWSADSQRVVFDSAQRSRQDLFAVDTQVGTVTSLTAGGSGGSWKLLTIDQDLMVAQFSTPSLPPTLKVGFLPSAGKEQSVLWVSLEEAEPIPDIHWGIRVLQPPPEQENVQYAGLDFEAILLQPGSPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDASHVALMGGSHGGFISCHLIGQYPETYRACVARNPVINIASMLGSTDIPDCSVSCRCVVEAGFPFSSDCLPDLSVWAEMLDKSPIRYIPQVKTPLLLMLGQEDRRVPFKQGMEYYRALKTRNVPVRLLLYPKSTHALSEVEVESDSFMNAVLWLRTHLGS 124 7.1 1 4 4 4 4 0.762 1.02 0.758 3 3 3 - - - 0.846666667 0.150124393 tr|C9JIF9|C9JIF9_HUMAN 99.19 0 gi|23510451|ref|NP_001631.3| acylamino-acid-releasing enzyme [Homo sapiens] >gi|38258902|sp|P13798.4|ACPH_HUMAN RecName: Full=Acylamino-acid-releasing enzyme; Short=AARE; AltName: Full=Acyl-peptide hydrolase; Short=APH; AltName: Full=Acylaminoacyl-peptidase; AltName: Full=Oxidized protein hydrolase; Short=OPH >gi|12653189|gb|AAH00362.1| N-acylaminoacyl-peptide hydrolase [Homo sapiens] >gi|12804773|gb|AAH01826.1| N-acylaminoacyl-peptide hydrolase [Homo sapiens] >gi|16306646|gb|AAH01499.1| N-acylaminoacyl-peptide hydrolase [Homo sapiens] >gi|119585399|gb|EAW64995.1| N-acylaminoacyl-peptide hydrolase, isoform CRA_b [Homo sapiens] >gi|119585400|gb|EAW64996.1| N-acylaminoacyl-peptide hydrolase, isoform CRA_b [Homo sapiens] 99.19 0 sp|P13798|ACPH_HUMAN Acylamino-acid-releasing enzyme OS=Homo sapiens GN=APEH PE=1 SV=4 100 0 C9JIF9 C9JIF9_HUMAN Acylamino-acid-releasing enzyme OS=Homo sapiens GN=APEH PE=4 SV=1 BS_yuxL 129 1.00E-29 COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases E Amino acid transport and metabolism ; K01303|1|0.0|1481|hsa:327|acylaminoacyl-peptidase [EC:3.4.19.1] GO:0006508//proteolysis GO:0004252//serine-type endopeptidase activity GO:0005737//cytoplasm;GO:0031965//nuclear membrane 461 sp|P51884|LUM_HUMAN Lumican OS=Homo sapiens GN=LUM PE=1 SV=2 46656 MSLSAFTLFLALIGGTSGQYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN 2236 33.4 - 147 147 10 10 1.702 1.58 2.138 77 77 75 - - - 1.806666667 0.293355302 sp|P51884|LUM_HUMAN 100 0 gi|4505047|ref|NP_002336.1| lumican precursor [Homo sapiens] >gi|20141464|sp|P51884.2|LUM_HUMAN RecName: Full=Lumican; AltName: Full=Keratan sulfate proteoglycan lumican; Short=KSPG lumican; Flags: Precursor >gi|699577|gb|AAA91639.1| lumican [Homo sapiens] >gi|13937865|gb|AAH07038.1| Lumican [Homo sapiens] >gi|23271183|gb|AAH35997.1| Lumican [Homo sapiens] >gi|30582253|gb|AAP35353.1| lumican [Homo sapiens] >gi|119617855|gb|EAW97449.1| lumican [Homo sapiens] 100 0 sp|P51884|LUM_HUMAN Lumican OS=Homo sapiens GN=LUM PE=1 SV=2 99.7 0 Q53FV4 Q53FV4_HUMAN Lumican variant (Fragment) OS=Homo sapiens PE=2 SV=1 alr0124_1 66.2 7.00E-11 COG4886 Leucine-rich repeat (LRR) protein S Function unknown ; K08122|1|0.0|647|hsa:4060|lumican GO:0070848//response to growth factor stimulus;GO:0051216//cartilage development;GO:0018146//keratan sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0007601//visual perception;GO:0014070//response to organic cyclic compound;GO:0030199//collagen fibril organization;GO:0044281//small molecule metabolic process;GO:0042340//keratan sulfate catabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter GO:0005201//extracellular matrix structural constituent;GO:0005518//collagen binding GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0043202//lysosomal lumen;GO:0005583//fibrillar collagen 462 tr|B3KRV6|B3KRV6_HUMAN cDNA FLJ34961 fis, clone NTONG2003839, highly similar to CONNECTIVE TISSUE GROWTH FACTOR OS=Homo sapiens PE=2 SV=1 42581 MTAASMGPVRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVRDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKIPKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA 592 24.9 2 31 31 6 6 0.406 0.484 0.379 20 20 19 * - * 0.423 0.054525224 tr|B3KRV6|B3KRV6_HUMAN 100 2.00E-175 gi|193787312|dbj|BAG52518.1| unnamed protein product [Homo sapiens] 98.31 3.00E-168 sp|P29279|CTGF_HUMAN Connective tissue growth factor OS=Homo sapiens GN=CTGF PE=1 SV=2 100 8.00E-175 B3KRV6 B3KRV6_HUMAN cDNA FLJ34961 fis, clone NTONG2003839, highly similar to CONNECTIVE TISSUE GROWTH FACTOR OS=Homo sapiens PE=2 SV=1 - - - - - - - K06827|1|6e-169|593|hsa:1490|connective tissue growth factor GO:0008284//positive regulation of cell proliferation;GO:0043434//response to peptide hormone stimulus;GO:0007160//cell-matrix adhesion;GO:0060401//cytosolic calcium ion transport;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0009749//response to glucose stimulus;GO:0001558//regulation of cell growth;GO:0070278//extracellular matrix constituent secretion;GO:0014070//response to organic cyclic compound;GO:0010260//organ senescence;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0072593//reactive oxygen species metabolic process;GO:0001503//ossification;GO:0016477//cell migration;GO:0008544//epidermis development;GO:0043200//response to amino acid stimulus;GO:0001934//positive regulation of protein phosphorylation;GO:0045597//positive regulation of cell differentiation;GO:0044255//cellular lipid metabolic process;GO:0050867//positive regulation of cell activation;GO:0044281//small molecule metabolic process;GO:0051496//positive regulation of stress fiber assembly;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006260//DNA replication;GO:0010942//positive regulation of cell death;GO:0070318//positive regulation of G0 to G1 transition;GO:0001525//angiogenesis;GO:0046330//positive regulation of JNK cascade;GO:0007229//integrin-mediated signaling pathway;GO:0010628//positive regulation of gene expression;GO:0051385//response to mineralocorticoid stimulus;GO:0032355//response to estradiol stimulus;GO:0060452//positive regulation of cardiac muscle contraction;GO:0070542//response to fatty acid;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0001502//cartilage condensation;GO:0009611//response to wounding;GO:0032967//positive regulation of collagen biosynthetic process;GO:0030324//lung development;GO:0034059//response to anoxia GO:0008201//heparin binding;GO:0005178//integrin binding;GO:0008083//growth factor activity;GO:0001968//fibronectin binding;GO:0005520//insulin-like growth factor binding GO:0005829//cytosol;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix;GO:0048471//perinuclear region of cytoplasm;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005938//cell cortex 463 tr|B4DDQ2|B4DDQ2_HUMAN cDNA FLJ55187, highly similar to Biglycan OS=Homo sapiens PE=2 SV=1 45295 MMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGNYKK 853 32 4 40 40 9 9 1.324 1.828 1.88 29 29 30 * * * 1.677333333 0.307098247 tr|B4DDQ2|B4DDQ2_HUMAN 100 5.00E-104 gi|119593271|gb|EAW72865.1| biglycan, isoform CRA_d [Homo sapiens] 100 0 sp|P21810|PGS1_HUMAN Biglycan OS=Homo sapiens GN=BGN PE=1 SV=2 100 2.00E-118 B4DNL4 B4DNL4_HUMAN cDNA FLJ59360, moderately similar to Biglycan OS=Homo sapiens PE=2 SV=1 alr0124_1 63.9 3.00E-10 COG4886 Leucine-rich repeat (LRR) protein S Function unknown ; K08118|1|0.0|685|hsa:633|biglycan GO:0030207//chondroitin sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0001974//blood vessel remodeling;GO:0030208//dermatan sulfate biosynthetic process;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0044281//small molecule metabolic process GO:0050840//extracellular matrix binding;GO:0005539//glycosaminoglycan binding;GO:0005201//extracellular matrix structural constituent GO:0005796//Golgi lumen;GO:0030133//transport vesicle;GO:0043202//lysosomal lumen;GO:0009986//cell surface;GO:0042383//sarcolemma;GO:0005578//proteinaceous extracellular matrix 464 sp|P13521|SCG2_HUMAN Secretogranin-2 OS=Homo sapiens GN=SCG2 PE=1 SV=2 83978 MAEAKTHWLGAALSLIPLIFLISGAEAASFQRNQLLQKEPDLRLENVQKFPSPEMIRALEYIENLRQQAHKEESSPDYNPYQGVSVPLQQKENGDESHLPERDSLSEEDWMRIILEALRQAENEPQSAPKENKPYALNSEKNFPMDMSDDYETQQWPERKLKHMQFPPMYEENSRDNPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPNNQKRERMDEEQKLYTDDEDDIYKANNIAYEDVVGGEDWNPVEEKIESQTQEEVRDSKENIEKNEQINDEMKRSGQLGIQEEDLRKESKDQLSDDVSKVIAYLKRLVNAAGSGRLQNGQNGERATRLFEKPLDSQSIYQLIEISRNLQIPPEDLIEMLKTGEKPNGSVEPERELDLPVDLDDISEADLDHPDLFQNRMLSKSGYPKTPGRAGTEALPDGLSVEDILNLLGMESAANQKTSYFPNPYNQEKVLPRLPYGAGRSRSNQLPKAAWIPHVENRQMAYENLNDKDQELGEYLARMLVKYPEIINSNQVKRVPGQGSSEDDLQEEEQIEQAIKEHLNQGSSQETDKLAPVSKRFPVGPPKNDDTPNRQYWDEDLLMKVLEYLNQEKAEKGREHIAKRAMENM 138 8.3 - 10 10 5 5 0.473 0.326 0.347 8 8 8 * - * 0.382 0.079504717 sp|P13521|SCG2_HUMAN 100 0 gi|68160947|ref|NP_003460.2| secretogranin-2 precursor [Homo sapiens] >gi|143811457|sp|P13521.2|SCG2_HUMAN RecName: Full=Secretogranin-2; AltName: Full=Chromogranin-C; AltName: Full=Secretogranin II; Short=SgII; Contains: RecName: Full=Secretoneurin; Short=SN; Flags: Precursor >gi|119591217|gb|EAW70811.1| secretogranin II (chromogranin C) [Homo sapiens] 100 0 sp|P13521|SCG2_HUMAN Secretogranin-2 OS=Homo sapiens GN=SCG2 PE=1 SV=2 100 9.00E-77 C9JQI2 C9JQI2_HUMAN Secretoneurin (Fragment) OS=Homo sapiens GN=SCG2 PE=4 SV=1 - - - - - - - - GO:0032925//regulation of activin receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0048704//embryonic skeletal system morphogenesis;GO:0006954//inflammatory response;GO:0046329//negative regulation of JNK cascade;GO:0030097//hemopoiesis;GO:0006281//DNA repair;GO:0032092//positive regulation of protein binding;GO:0045669//positive regulation of osteoblast differentiation;GO:0010332//response to gamma radiation;GO:0001776//leukocyte homeostasis;GO:0007420//brain development;GO:0051974//negative regulation of telomerase activity;GO:0034968//histone lysine methylation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045668//negative regulation of osteoblast differentiation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0051781//positive regulation of cell division;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0060135//maternal process involved in female pregnancy;GO:0009411//response to UV;GO:0043542//endothelial cell migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050930//induction of positive chemotaxis;GO:0001937//negative regulation of endothelial cell proliferation;GO:0002051//osteoblast fate commitment;GO:0031062//positive regulation of histone methylation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0046621//negative regulation of organ growth;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007050//cell cycle arrest;GO:0001525//angiogenesis;GO:0006338//chromatin remodeling;GO:0060021//palate development;GO:0043066//negative regulation of apoptotic process;GO:0048245//eosinophil chemotaxis;GO:0002076//osteoblast development;GO:0009306//protein secretion;GO:0001938//positive regulation of endothelial cell proliferation GO:0047485//protein N-terminus binding;GO:0003690//double-stranded DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0005125//cytokine activity;GO:0000403//Y-form DNA binding;GO:0003682//chromatin binding;GO:0000400//four-way junction DNA binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0030674//protein binding, bridging;GO:0042056//chemoattractant activity;GO:0070412//R-SMAD binding GO:0016363//nuclear matrix;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0032154//cleavage furrow;GO:0030141//secretory granule;GO:0035097//histone methyltransferase complex;GO:0000785//chromatin;GO:0005730//nucleolus 465 tr|A0A0A0MSS8|A0A0A0MSS8_HUMAN Aldo-keto reductase family 1 member C3 OS=Homo sapiens GN=AKR1C3 PE=4 SV=1 45457 MDSKHQCLKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYSDEY 59 7.4 3 3 3 2 2 0.702 1.069 1.394 3 3 3 - - - 1.055 0.346212363 tr|A0A0A0MSS8|A0A0A0MSS8_HUMAN 100 0 gi|359806990|ref|NP_001240837.1| aldo-keto reductase family 1 member C3 isoform 2 [Homo sapiens] 99.69 0 sp|P42330|AK1C3_HUMAN Aldo-keto reductase family 1 member C3 OS=Homo sapiens GN=AKR1C3 PE=1 SV=4 100 1.00E-117 B4DL37 B4DL37_HUMAN Aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II), isoform CRA_c OS=Homo sapiens GN=AKR1C3 PE=2 SV=1 YOR120w 211 1.00E-54 COG0656 Aldo/keto reductases, related to diketogulonate reductase R General function prediction only ; K00089|1|0.0|673|hsa:8644|3alpha-hydroxysteroid dehydrogenase (A-specific) [EC:1.1.1.213] K00212 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [EC:1.3.1.20] K04119 prostaglandin-F synthase [EC:1.1.1.188]!K00037|3|1e-161|568|hsa:1109|3-alpha-hydroxysteroid dehydrogenase [EC:1.1.1.50] K00089 3alpha-hydroxysteroid dehydrogenase (A-specific) [EC:1.1.1.213] K00092 chlordecone reductase [EC:1.1.1.225] K00212 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [EC:1.3.1.20]!K00100|4|2e-149|528|mmu:83702|[EC:1.1.1.-]!K05295|5|5e-142|503|mmu:105349|20alpha-hydroxysteroid dehydrogenase [EC:1.1.1.149] GO:0034614//cellular response to reactive oxygen species;GO:0008284//positive regulation of cell proliferation;GO:0007584//response to nutrient;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:1900053//negative regulation of retinoic acid biosynthetic process;GO:0044597//daunorubicin metabolic process;GO:0000060//protein import into nucleus, translocation;GO:0044598//doxorubicin metabolic process;GO:0070293//renal absorption;GO:0071277//cellular response to calcium ion;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:2000224//regulation of testosterone biosynthetic process;GO:0030216//keratinocyte differentiation;GO:0055114//oxidation-reduction process;GO:0006693//prostaglandin metabolic process;GO:0009267//cellular response to starvation;GO:0071379//cellular response to prostaglandin stimulus;GO:0016488//farnesol catabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008584//male gonad development;GO:0071395//cellular response to jasmonic acid stimulus;GO:0071384//cellular response to corticosteroid stimulus;GO:0051897//positive regulation of protein kinase B signaling cascade;GO:0044259//multicellular organismal macromolecule metabolic process;GO:0042574//retinal metabolic process;GO:0071276//cellular response to cadmium ion;GO:0042448//progesterone metabolic process;GO:0048385//regulation of retinoic acid receptor signaling pathway GO:0050327//testosterone 17-beta-dehydrogenase (NAD+) activity;GO:0047787//delta4-3-oxosteroid 5beta-reductase activity;GO:0047026//androsterone dehydrogenase (A-specific) activity;GO:0045703//ketoreductase activity;GO:0045550//geranylgeranyl reductase activity;GO:0047115//trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0004745//retinol dehydrogenase activity;GO:0047086//ketosteroid monooxygenase activity;GO:0004958//prostaglandin F receptor activity;GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity;GO:0001758//retinal dehydrogenase activity;GO:0036131//prostaglandin D2 11-ketoreductase activity;GO:0018636//phenanthrene 9,10-monooxygenase activity;GO:0035410//dihydrotestosterone 17-beta-dehydrogenase activity;GO:0047020//15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0047017//prostaglandin-F synthase activity;GO:0047718//indanol dehydrogenase activity GO:0005737//cytoplasm;GO:0005634//nucleus 466 tr|B7Z4X6|B7Z4X6_HUMAN cDNA FLJ51012, highly similar to Plasminogen activator inhibitor 1 OS=Homo sapiens PE=2 SV=1 43747 MLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDIPFLFVVRHNPTGTVLFMGQVMEP 2061 49 2 125 125 13 13 0.416 0.226 0.252 70 75 64 * - - 0.298 0.103014562 tr|B7Z4X6|B7Z4X6_HUMAN 100 3.00E-180 gi|221042070|dbj|BAH12712.1| unnamed protein product [Homo sapiens] 99.69 2.00E-180 sp|P05121|PAI1_HUMAN Plasminogen activator inhibitor 1 OS=Homo sapiens GN=SERPINE1 PE=1 SV=1 100 1.00E-179 B7Z4X6 B7Z4X6_HUMAN cDNA FLJ51012, highly similar to Plasminogen activator inhibitor 1 OS=Homo sapiens PE=2 SV=1 all0778 150 3.00E-36 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K03982|1|0.0|634|ptr:472467|plasminogen activator inhibitor-1 GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001300//chronological cell aging;GO:0071258//cellular response to gravity;GO:0061044//negative regulation of vascular wound healing;GO:0051384//response to glucocorticoid stimulus;GO:0045766//positive regulation of angiogenesis;GO:0030168//platelet activation;GO:0051918//negative regulation of fibrinolysis;GO:0010469//regulation of receptor activity;GO:0042593//glucose homeostasis;GO:0010757//negative regulation of plasminogen activation;GO:0035491//positive regulation of leukotriene production involved in inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042127//regulation of cell proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:0014912//negative regulation of smooth muscle cell migration;GO:0042246//tissue regeneration;GO:0002576//platelet degranulation;GO:0090026//positive regulation of monocyte chemotaxis;GO:0000302//response to reactive oxygen species;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0043627//response to estrogen stimulus;GO:0010951//negative regulation of endopeptidase activity;GO:0055093//response to hyperoxia;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0032757//positive regulation of interleukin-8 production;GO:2000098//negative regulation of smooth muscle cell-matrix adhesion;GO:0050829//defense response to Gram-negative bacterium;GO:0043066//negative regulation of apoptotic process;GO:0034097//response to cytokine stimulus GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005102//receptor binding;GO:0002020//protease binding GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0031012//extracellular matrix 467 tr|D3DP16|D3DP16_HUMAN Fibrinogen gamma chain, isoform CRA_a OS=Homo sapiens GN=FGG PE=4 SV=1 46878 MIDAATLKSRKMLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGEGQQHHLGGAKQAGDV 82 14.7 4 9 9 5 5 --- 1.163 --- 1 2 1 - - - 1.163 - tr|D3DP16|D3DP16_HUMAN 100 0 gi|119625326|gb|EAX04921.1| fibrinogen gamma chain, isoform CRA_o [Homo sapiens] 99.7 0 sp|P02679|FIBG_HUMAN Fibrinogen gamma chain OS=Homo sapiens GN=FGG PE=1 SV=3 100 0 Q7Z664 Q7Z664_HUMAN Putative uncharacterized protein DKFZp779N0926 (Fragment) OS=Homo sapiens GN=DKFZp779N0926 PE=2 SV=1 - - - - - - - K03905|1|0.0|650|hsa:2266|fibrinogen gamma chain GO:0030168//platelet activation;GO:0051258//protein polymerization;GO:0007165//signal transduction;GO:0002576//platelet degranulation;GO:0051592//response to calcium ion GO:0030674//protein binding, bridging;GO:0043499//eukaryotic cell surface binding;GO:0005102//receptor binding GO:0009897//external side of plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0005938//cell cortex;GO:0005577//fibrinogen complex 468 tr|Q6FHN2|Q6FHN2_HUMAN CTSK protein (Fragment) OS=Homo sapiens GN=CTSK PE=2 SV=1 46187 MWGLKVLLLPVVSLALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 358 24 1 10 10 5 5 0.712 0.412 0.533 10 10 10 - * * 0.552333333 0.150931552 tr|Q6FHN2|Q6FHN2_HUMAN 100 3.00E-123 gi|315364648|pdb|3OVZ|A Chain A, Cathepsin K In Complex With A Covalent Inhibitor With A Ketoamide Warhead 99.7 0 sp|P43235|CATK_HUMAN Cathepsin K OS=Homo sapiens GN=CTSK PE=1 SV=1 100 0 Q6FHN2 Q6FHN2_HUMAN CTSK protein (Fragment) OS=Homo sapiens GN=CTSK PE=2 SV=1 AF1946_2 83.2 7.00E-16 COG4870 Cysteine protease O Posttranslational modification, protein turnover, chaperones ; K01371|1|0.0|683|hsa:1513|cathepsin K [EC:3.4.22.38] GO:0045087//innate immune response;GO:0001957//intramembranous ossification;GO:0045453//bone resorption;GO:0006508//proteolysis GO:0004197//cysteine-type endopeptidase activity GO:0005615//extracellular space;GO:0036021//endolysosome lumen 469 tr|A5YM53|A5YM53_HUMAN ITGAV protein OS=Homo sapiens GN=ITGAV PE=2 SV=1 132877 MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNRTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET 47 2.2 1 2 2 2 2 0.603 0.552 1.156 2 2 2 - - - 0.770333333 0.334969153 tr|A5YM53|A5YM53_HUMAN 100 0 gi|148342506|gb|ABQ59037.1| ITGAV protein [Homo sapiens] 99.8 0 sp|P06756|ITAV_HUMAN Integrin alpha-V OS=Homo sapiens GN=ITGAV PE=1 SV=2 100 0 A5YM53 A5YM53_HUMAN ITGAV protein OS=Homo sapiens GN=ITGAV PE=2 SV=1 - - - - - - - K06487|1|0.0|2043|ptr:459807|integrin alpha V GO:2000536//negative regulation of entry of bacterium into host cell;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0007160//cell-matrix adhesion;GO:0007411//axon guidance;GO:0050748//negative regulation of lipoprotein metabolic process;GO:2000425//regulation of apoptotic cell clearance;GO:0045785//positive regulation of cell adhesion;GO:0007596//blood coagulation;GO:0045715//negative regulation of low-density lipoprotein particle receptor biosynthetic process;GO:0070371//ERK1 and ERK2 cascade;GO:0050900//leukocyte migration;GO:0052066//entry of symbiont into host cell by promotion of host phagocytosis;GO:0030335//positive regulation of cell migration;GO:0032369//negative regulation of lipid transport;GO:0007229//integrin-mediated signaling pathway;GO:0001525//angiogenesis;GO:0046718//viral entry into host cell;GO:0043066//negative regulation of apoptotic process;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0010888//negative regulation of lipid storage;GO:0033690//positive regulation of osteoblast proliferation GO:0005080//protein kinase C binding;GO:0005245//voltage-gated calcium channel activity;GO:0031994//insulin-like growth factor I binding;GO:0050431//transforming growth factor beta binding;GO:0001846//opsonin binding GO:0035867//alphav-beta3 integrin-IGF-1-IGF1R complex;GO:0045335//phagocytic vesicle;GO:0009897//external side of plasma membrane;GO:0008305//integrin complex 470 tr|S4R371|S4R371_HUMAN Fatty acid-binding protein, heart (Fragment) OS=Homo sapiens GN=FABP3 PE=1 SV=1 19398 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKE 95 6.8 3 3 3 1 1 1.664 2.6 1.848 2 2 2 - * - 2.037333333 0.495892461 tr|S4R371|S4R371_HUMAN 100 2.00E-70 gi|4758328|ref|NP_004093.1| fatty acid-binding protein, heart [Homo sapiens] >gi|119802|sp|P05413.4|FABPH_HUMAN RecName: Full=Fatty acid-binding protein, heart; AltName: Full=Fatty acid-binding protein 3; AltName: Full=Heart-type fatty acid-binding protein; Short=H-FABP; AltName: Full=Mammary-derived growth inhibitor; Short=MDGI; AltName: Full=Muscle fatty acid-binding protein; Short=M-FABP >gi|31293|emb|CAA39889.1| muscle fatty-acid-binding protein (FABP) [Homo sapiens] >gi|1377854|gb|AAB02555.1| fatty acid binding protein FABP [Homo sapiens] >gi|4096097|gb|AAC99800.1| fatty acid binding protein [Homo sapiens] >gi|13937837|gb|AAH07021.1| Fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) [Homo sapiens] >gi|30582293|gb|AAP35373.1| fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) [Homo sapiens] >gi|119628024|gb|EAX07619.1| fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor), isoform CRA_b [Homo sapiens] 100 3.00E-71 sp|P05413|FABPH_HUMAN Fatty acid-binding protein, heart OS=Homo sapiens GN=FABP3 PE=1 SV=4 100 1.00E-69 H2PYI9 H2PYI9_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000121769 PE=3 SV=1 - - - - - - - K08752|1|2e-71|266|pon:100448979|fatty acid-binding protein 3, muscle and heart GO:0008285//negative regulation of cell proliferation;GO:0042493//response to drug;GO:0070542//response to fatty acid;GO:0006810//transport;GO:0006631//fatty acid metabolic process;GO:0032868//response to insulin stimulus GO:0005324//long-chain fatty acid transporter activity;GO:0050543//icosatetraenoic acid binding;GO:0008092//cytoskeletal protein binding GO:0016528//sarcoplasm;GO:0005829//cytosol 471 tr|A8K2Y2|A8K2Y2_HUMAN cDNA FLJ78120, highly similar to Homo sapiens eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa (EIF2S3), mRNA OS=Homo sapiens PE=2 SV=1 62904 MAGGEAGVTLGQPHLSRQDLTTLDVTKLTPLSHEVISRQATIDIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD 92 12.5 2 4 4 4 4 0.744 0.773 0.973 3 3 2 - - - 0.83 0.12468761 tr|A8K2Y2|A8K2Y2_HUMAN 100 0 gi|158261817|dbj|BAF83086.1| unnamed protein product [Homo sapiens] 99.79 0 sp|P41091|IF2G_HUMAN Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens GN=EIF2S3 PE=1 SV=3 100 0 Q9CRE9 Q9CRE9_MOUSE Putative uncharacterized protein (Fragment) OS=Mus musculus GN=Eif2s3x PE=2 SV=1 SPBC17G9.09 702 0 COG5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase) J Translation, ribosomal structure and biogenesis ; K03242|1|0.0|960|hsa:1968|translation initiation factor 2 subunit 3 GO:0006413//translational initiation;GO:0006184//GTP catabolic process GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding GO:0005829//cytosol 472 tr|B2RAY1|B2RAY1_HUMAN cDNA, FLJ95184, highly similar to Homo sapiens signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 (STAM), mRNA OS=Homo sapiens PE=2 SV=1 69246 MPLFATNPFDQDVEKATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVANKKEEEDLAKAIELSLKEQRQQSTTLSTLYPSTSSLLTNHQHEGRKVRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGIGLFPSNFVTADLTAEPEMIKTEKKTVQFSDDVQVETIEPEPEPAFIDEDKMDQLLQMLQSTDPSDDQPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNVDPMYSMYAKLQNQPYYMQSSGVSGSQVYAGPPPSGAYLVAGNAQMSHLQSYSLPPEQLSSLSQAVVPPSANPALPSQQTQAAYPNTMVSSVQGNTYPSQAPVYSPPPAATAAAATADVTLYQNAGPNMPQVPNYNLTSSTLPQPGGSQQPPQPQQPYSQKALL 121 5.4 1 5 5 2 2 1.159 0.75 0.712 3 4 4 - - - 0.873666667 0.247835295 tr|B2RAY1|B2RAY1_HUMAN 100 9.00E-36 gi|225734102|pdb|3F1I|S Chain S, Human Escrt-0 Core Complex >gi|225734103|pdb|3F1I|C Chain C, Human Escrt-0 Core Complex 99.81 0 sp|Q92783|STAM1_HUMAN Signal transducing adapter molecule 1 OS=Homo sapiens GN=STAM PE=1 SV=3 100 2.00E-93 A6NMU3 A6NMU3_HUMAN Signal transducing adapter molecule 1 (Fragment) OS=Homo sapiens GN=STAM PE=4 SV=1 - - - - - - - K04705|1|0.0|970|hsa:8027|signal transducing adaptor molecule GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0016044//cellular membrane organization;GO:0016197//endosomal transport;GO:0006886//intracellular protein transport GO:0005070//SH3/SH2 adaptor activity GO:0005829//cytosol;GO:0031901//early endosome membrane 473 tr|A0AV88|A0AV88_HUMAN ADAM10 protein OS=Homo sapiens GN=ADAM10 PE=2 SV=1 69724 MVLLRVLILLLSWAAGMGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRNISFMVKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSTVCIQVKV 96 4.5 1 5 5 2 2 0.865 1.201 1.132 2 2 2 - - - 1.066 0.177457037 tr|A0AV88|A0AV88_HUMAN 100 4.00E-107 gi|194390862|dbj|BAG62190.1| unnamed protein product [Homo sapiens] 100 8.00E-38 sp|O77633|ADA10_PIG Disintegrin and metalloproteinase domain-containing protein 10 (Fragment) OS=Sus scrofa GN=ADAM10 PE=2 SV=1 100 0 H9EQI5 H9EQI5_MACMU Disintegrin and metalloproteinase domain-containing protein 10 OS=Macaca mulatta GN=ADAM10 PE=2 SV=1 - - - - - - - K06704|1|0.0|1035|ptr:746942|disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81] GO:0051089//constitutive protein ectodomain proteolysis;GO:0042117//monocyte activation;GO:0030307//positive regulation of cell growth;GO:0045670//regulation of osteoclast differentiation;GO:0007219//Notch signaling pathway;GO:0007267//cell-cell signaling;GO:0006412//translation;GO:0007162//negative regulation of cell adhesion;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0010820//positive regulation of T cell chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0007220//Notch receptor processing;GO:0006468//protein phosphorylation;GO:0034612//response to tumor necrosis factor;GO:0051088//PMA-inducible membrane protein ectodomain proteolysis;GO:0001701//in utero embryonic development GO:0005178//integrin binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0004222//metalloendopeptidase activity;GO:0003735//structural constituent of ribosome;GO:0042803//protein homodimerization activity;GO:0017124//SH3 domain binding GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane;GO:0005840//ribosome;GO:0016021//integral to membrane;GO:0009986//cell surface;GO:0014069//postsynaptic density;GO:0005798//Golgi-associated vesicle;GO:0005886//plasma membrane;GO:0005634//nucleus 474 sp|O43776|SYNC_HUMAN Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens GN=NARS PE=1 SV=1 74709 MVLAELYVSDREGSDATGDGTKEKPFKTGLKALMTVGKEPFPTIYVDSQKENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKKITIKNDPSLPEPKCVKIGALEGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLADELCQCYNGVLLSTESSVAVYGMLNLTPKGKQAPGGHELSCDFWELIGLAPAGGADNLINEESDVDVQLNNRHMMIRGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLNRLEDLVCDVVDRILKSPAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYEFGEDIPEAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIFDSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYPRFVQRCTP 114 9.1 - 5 5 4 4 1.551 0.728 0.764 3 3 3 - - - 1.014333333 0.465115398 sp|O43776|SYNC_HUMAN 100 1.00E-175 gi|194387516|dbj|BAG60122.1| unnamed protein product [Homo sapiens] 100 0 sp|O43776|SYNC_HUMAN Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens GN=NARS PE=1 SV=1 100 5.00E-175 B4DN60 B4DN60_HUMAN Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens GN=NARS PE=2 SV=1 YHR019c 573 2.00E-163 COG0017 Aspartyl/asparaginyl-tRNA synthetases J Translation, ribosomal structure and biogenesis ; K01893|1|0.0|1143|hsa:4677|asparaginyl-tRNA synthetase [EC:6.1.1.22] GO:0006421//asparaginyl-tRNA aminoacylation GO:0003676//nucleic acid binding;GO:0004816//asparagine-tRNA ligase activity;GO:0005524//ATP binding GO:0005829//cytosol;GO:0005739//mitochondrion 475 tr|B4DWU3|B4DWU3_HUMAN cDNA FLJ53673, highly similar to Palmitoyl-protein thioesterase 1 (EC 3.1.2.22) OS=Homo sapiens PE=2 SV=1 31437 MGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDSEDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHIIPFLG 37 6 4 2 2 1 1 --- 0.989 0.887 1 2 2 - - - 0.938 0.072124892 tr|B4DWU3|B4DWU3_HUMAN 100 2.00E-135 gi|194377188|dbj|BAG63155.1| unnamed protein product [Homo sapiens] 90.62 8.00E-132 sp|P50897|PPT1_HUMAN Palmitoyl-protein thioesterase 1 OS=Homo sapiens GN=PPT1 PE=1 SV=1 100 8.00E-102 F7HMC5 F7HMC5_MACMU Uncharacterized protein (Fragment) OS=Macaca mulatta GN=Mmu.4145 PE=4 SV=1 SPBC530.12c_1 109 3.00E-24 COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold R General function prediction only ; K01074|1|8e-132|469|hsa:5538|palmitoyl-protein thioesterase [EC:3.1.2.22] GO:0044257//cellular protein catabolic process;GO:0048666//neuron development;GO:0050803//regulation of synapse structure and activity;GO:0051181//cofactor transport;GO:0007269//neurotransmitter secretion;GO:0007625//grooming behavior;GO:0048549//positive regulation of pinocytosis;GO:0015031//protein transport;GO:0008306//associative learning;GO:0007042//lysosomal lumen acidification;GO:0007420//brain development;GO:0006309//apoptotic DNA fragmentation;GO:0007601//visual perception;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0030308//negative regulation of cell growth;GO:0002084//protein depalmitoylation;GO:0051186//cofactor metabolic process;GO:0032429//regulation of phospholipase A2 activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0031579//membrane raft organization;GO:0030149//sphingolipid catabolic process;GO:0008344//adult locomotory behavior GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity GO:0045121//membrane raft;GO:0005615//extracellular space;GO:0005764//lysosome;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0030424//axon;GO:0008021//synaptic vesicle;GO:0005634//nucleus 476 tr|A0A087WYY1|A0A087WYY1_HUMAN Carboxypeptidase Q OS=Homo sapiens GN=CPQ PE=4 SV=1 69898 MKFLIFAFFGGVHLLSLCSGKAICKNGISKRTFEEIKEEIASCGDVAKAIINLAVYGKAQNRSYERLALLVDTVGPRLSGSKNLEKAIQIMYQNLQQDGLEKVHLEPVRIPHWERGEESAVMLEPRIHKIAILGLGSSIGTPPEGITAEVLVVTSFDELQRRASEARGKIVVYNQPYINYSRTVQYRTQGAVEAAKVGALASLIRSVASFSIYSPHTGIQEYQDGVPKIPTACITVEDAEMMSRMASHGIKIVIQLKMGAKTYPDTDSFNTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWEALSLIKDLGLRPKRTLRLVLWTAEEQGGVGAFQYYQLHKVNISNYSLVMESDAGTFLPTGLQFTGSEKARAIMEEVMSLLQPLNITQVLSHGEGTDINFWIQAGVPGASLLDDLYKYFFFHHSHGDTMTVMDPSRMLLLLFGLLFLMLLQTWKKCCLGPRNSKKETFSCFWPGILGLQLWKTPLHITISSNSSSKHNSISCFLLLSFLILSKFSDSRKRNHSPLPPTT 392 19.1 1 29 29 7 7 1.495 1.351 1.676 16 14 16 - * * 1.507333333 0.162850647 tr|A0A087WYY1|A0A087WYY1_HUMAN 100 6.00E-30 gi|297683348|ref|XP_002819349.1| PREDICTED: carboxypeptidase Q-like, partial [Pongo abelii] 99.55 0 sp|Q9Y646|CBPQ_HUMAN Carboxypeptidase Q OS=Homo sapiens GN=CPQ PE=1 SV=1 100 2.00E-70 E5RJZ7 E5RJZ7_HUMAN Protein PGCP (Fragment) OS=Homo sapiens GN=PGCP PE=4 SV=1 CC2544 233 5.00E-61 COG2234 Predicted aminopeptidases R General function prediction only ; K14592|1|6e-08|59.7|mmu:53320|folate hydrolase 1 [EC:3.4.17.21]!K01301|2|2e-07|57.8|tad:TRIADDRAFT_64334|glutamate carboxypeptidase II [EC:3.4.17.21]!K06503|3|1e-06|55.1|mgp:100550142|transferrin receptor GO:0043171//peptide catabolic process;GO:0006508//proteolysis;GO:0006590//thyroid hormone generation;GO:0042246//tissue regeneration GO:0004180//carboxypeptidase activity;GO:0046872//metal ion binding;GO:0070573//metallodipeptidase activity;GO:0042803//protein homodimerization activity GO:0005764//lysosome;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus 477 tr|Q0QF37|Q0QF37_HUMAN Malate dehydrogenase (Fragment) OS=Homo sapiens GN=MDH2 PE=2 SV=1 39402 QNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKAS 243 30.5 3 10 10 7 7 0.861 0.886 0.65 10 9 8 - - * 0.799 0.129641814 tr|Q0QF37|Q0QF37_HUMAN 100 2.00E-176 gi|21735621|ref|NP_005909.2| malate dehydrogenase, mitochondrial precursor [Homo sapiens] >gi|215274114|sp|P40926.3|MDHM_HUMAN RecName: Full=Malate dehydrogenase, mitochondrial; Flags: Precursor >gi|119592202|gb|EAW71796.1| malate dehydrogenase 2, NAD (mitochondrial), isoform CRA_a [Homo sapiens] >gi|119592204|gb|EAW71798.1| malate dehydrogenase 2, NAD (mitochondrial), isoform CRA_a [Homo sapiens] 100 2.00E-177 sp|P40926|MDHM_HUMAN Malate dehydrogenase, mitochondrial OS=Homo sapiens GN=MDH2 PE=1 SV=3 100 4.00E-176 Q6FHZ0 Q6FHZ0_HUMAN Malate dehydrogenase OS=Homo sapiens GN=MDH2 PE=2 SV=1 mdh 334 1.00E-91 COG0039 Malate/lactate dehydrogenases C Energy production and conversion ; K00026|1|2e-177|621|hsa:4191|malate dehydrogenase [EC:1.1.1.37] GO:0006107//oxaloacetate metabolic process;GO:0006734//NADH metabolic process;GO:0006108//malate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0044262//cellular carbohydrate metabolic process;GO:0006475//internal protein amino acid acetylation;GO:0006094//gluconeogenesis GO:0030060//L-malate dehydrogenase activity;GO:0043621//protein self-association;GO:0046554//malate dehydrogenase (NADP+) activity;GO:0000166//nucleotide binding GO:0005730//nucleolus;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane 478 tr|V9HW11|V9HW11_HUMAN Epididymis secretory sperm binding protein Li 83p OS=Homo sapiens GN=HEL-S-83p PE=2 SV=1 61190 MGSPAHRPALLLLLPPLLLLLLRVPPSRSFPGSGDSPLEDDEVGYSHPRYKDTPWCSPIKVKYGDVYCRAPQGGYYKTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVICKQKRCPTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGASLLCGYGPPRIKCPSVKERIAEPNKLTVRVWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRLQLGMLQQAQCGLDLRHITVVELVGVFPTLIGRIGAKIMPPALALQLRLLLRIPLYSFSMVLVDKHGMDKERYVSLVMPVALFNLIDTFPLRKEEMVLQAEMSQTCNT 274 10 1 14 14 4 4 2.672 2.643 1.965 10 10 9 * * * 2.426666667 0.400077909 tr|V9HW11|V9HW11_HUMAN 100 0 gi|1778410|gb|AAB40715.1| a novel protein with short consensus repeats of six cysteines; the protein has three short consensus repeats (SCR), which is a motif of approximately 60 amino acids [Homo sapiens] 97.84 0 sp|P78539|SRPX_HUMAN Sushi repeat-containing protein SRPX OS=Homo sapiens GN=SRPX PE=2 SV=1 98.06 0 F6VV44 F6VV44_CALJA Uncharacterized protein OS=Callithrix jacchus GN=SRPX PE=4 SV=1 - - - - - - - K14407|1|2e-95|350|oaa:100082393|cleavage stimulation factor subunit 2!K06494|2|4e-19|96.7|gga:424402|selectin, endothelial cell!K06496|5|5e-19|96.3|gga:424364|selectin, platele GO:0007155//cell adhesion - GO:0009986//cell surface;GO:0016020//membrane 479 sp|Q9Y6C2|EMIL1_HUMAN EMILIN-1 OS=Homo sapiens GN=EMILIN1 PE=1 SV=2 111563 MAPRTLWSCYLCCLLTAAAGAASYPPRGFSLYTGSSGALSPGGPQAQIAPRPASRHRNWCAYVVTRTVSCVLEDGVETYVKYQPCAWGQPQCPQSIMYRRFLRPRYRVAYKTVTDMEWRCCQGYGGDDCAESPAPALGPASSTPRPLAQPARPNLSGSSAGSPLSGLGGEGPGESEKVQQLEEQVQSLTKELQGLRGVLQGLSGRLAEDVQRAVETAFNGRQQPADAAARPGVHETLNEIQHQLQLLDTRVSTHDQELGHLNNHHGGSSSSGGSRAPAPASAPPGPSEELLRQLEQRLQESCSVCLAGLDGFRRQQQEDRERLRAMEKLLASVEERQRHLAGLAVGRRPPQECCSPELGRRLAELERRLDVVAGSVTVLSGRRGTELGGAAGQGGHPPGYTSLASRLSRLEDRFNSTLGPSEEQEESWPGAPGGLSHWLPAARGRLEQLGGLLANVSGELGGRLDLLEEQVAGAMQACGQLCSGAPGEQDSQVSEILSALERRVLDSEGQLRLVGSGLHTVEAAGEARQATLEGLQEVVGRLQDRVDAQDETAAEFTLRLNLTAARLGQLEGLLQAHGDEGCGACGGVQEELGRLRDGVERCSCPLLPPRGPGAGPGVGGPSRGPLDGFSVFGGSSGSALQALQGELSEVILSFSSLNDSLNELQTTVEGQGADLADLGATKDRIISEINRLQQEATEHATESEERFRGLEEGQAQAGQCPSLEGRLGRLEGVCERLDTVAGGLQGLREGLSRHVAGLWAGLRETNTTSQMQAALLEKLVGGQAGLGRRLGALNSSLQLLEDRLHQLSLKDLTGPAGEAGPPGPPGLQGPPGPAGPPGSPGKDGQEGPIGPPGPQGEQGVEGAPAAPVPQVAFSAALSLPRSEPGTVPFDRVLLNDGGYYDPETGVFTAPLAGRYLLSAVLTGHRHEKVEAVLSRSNQGVARVDSGGYEPEGLENKPVAESQPSPGTLGVFSLILPLQAGDTVCVDLVMGQLAHSEEPLTIFSGALLYGDPELEHA 1372 17.4 - 51 51 13 13 1.402 1.667 1.971 36 37 38 * * * 1.68 0.284722672 sp|Q9Y6C2|EMIL1_HUMAN 100 0 gi|205371751|sp|Q9Y6C2.2|EMIL1_HUMAN RecName: Full=EMILIN-1; AltName: Full=Elastin microfibril interface-located protein 1; Short=Elastin microfibril interfacer 1; Flags: Precursor 100 0 sp|Q9Y6C2|EMIL1_HUMAN EMILIN-1 OS=Homo sapiens GN=EMILIN1 PE=1 SV=2 100 1.00E-56 H0Y7A0 H0Y7A0_HUMAN EMILIN-1 (Fragment) OS=Homo sapiens GN=EMILIN1 PE=4 SV=1 - - - - - - - - GO:0007155//cell adhesion GO:0005515//protein binding GO:0031012//extracellular matrix 480 tr|K7EM18|K7EM18_HUMAN Eukaryotic translation initiation factor 1 OS=Homo sapiens GN=EIF1 PE=1 SV=1 18029 MSAIQNLHSFDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLVEIGLAKDDQLKVHGFKNLTACIM 58 36.4 1 3 3 3 3 1.412 0.692 0.842 3 3 3 - - - 0.982 0.379868398 tr|K7EM18|K7EM18_HUMAN 100 5.00E-45 gi|449267637|gb|EMC78558.1| Eukaryotic translation initiation factor 1, partial [Columba livia] 100 3.00E-52 sp|Q5RFF4|EIF1_PONAB Eukaryotic translation initiation factor 1 OS=Pongo abelii GN=EIF1 PE=3 SV=1 100 1.00E-50 G1SDN3 G1SDN3_RABIT Uncharacterized protein OS=Oryctolagus cuniculus GN=EIF1 PE=4 SV=1 YNL244c 139 1.00E-33 COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related proteins J Translation, ribosomal structure and biogenesis ; K03113|1|8e-54|208|ptr:454665|translation initiation factor 1 GO:0006950//response to stress;GO:0006446//regulation of translational initiation;GO:0009048//dosage compensation by inactivation of X chromosome GO:0003743//translation initiation factor activity GO:0005737//cytoplasm 481 tr|A0A087WSV8|A0A087WSV8_HUMAN Nucleobindin 2, isoform CRA_b OS=Homo sapiens GN=NUCB2 PE=1 SV=1 65521 MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYLKQVIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLIKAKLDSLQDIGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEEFKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREHVMNEVDTNKDRLVTLEEFLKATEKKEFLEPDSWETLDQQQFFTEEELKEYENIIALQENELKKKADELQKQKEELQRQHDQLEAQKLEYHQVIQQMEQKKLQQGIPPSGPAGELKFEPRV 278 17.1 3 17 17 5 5 1.28 0.953 1.265 12 13 14 * - - 1.166 0.184615817 tr|A0A087WSV8|A0A087WSV8_HUMAN 100 0 gi|119588847|gb|EAW68441.1| nucleobindin 2, isoform CRA_b [Homo sapiens] 99.29 0 sp|P80303|NUCB2_HUMAN Nucleobindin-2 OS=Homo sapiens GN=NUCB2 PE=1 SV=2 100 3.00E-15 E9PRQ3 E9PRQ3_HUMAN Nucleobindin-2 (Fragment) OS=Homo sapiens GN=NUCB2 PE=4 SV=1 - - - - - - - K12385|1|5e-70|265|isc:IscW_ISCW020300|Niemann-Pick C1 protein - GO:0003677//DNA binding;GO:0005509//calcium ion binding;GO:0005164//tumor necrosis factor receptor binding GO:0005797//Golgi medial cisterna;GO:0005615//extracellular space;GO:0005640//nuclear outer membrane;GO:0005886//plasma membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum 482 sp|P55072|TERA_HUMAN Transitional endoplasmic reticulum ATPase OS=Homo sapiens GN=VCP PE=1 SV=4 >tr|V9HW80|V9HW80_HUMAN Epididymis luminal protein 220 OS=Homo sapiens GN=HEL-S-70 PE=2 SV=1 104552 MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGSFRFPSGNQGGAGPSQGSGGGTGGSVYTEDNDDDLYG 140 8.4 - 13 13 6 6 1.001 1.35 0.801 6 6 6 - * - 1.050666667 0.27784948 sp|P55072|TERA_HUMAN 100 0 gi|6005942|ref|NP_009057.1| transitional endoplasmic reticulum ATPase [Homo sapiens] >gi|225543319|ref|NP_033529.3| transitional endoplasmic reticulum ATPase [Mus musculus] >gi|6094447|sp|P55072.4|TERA_HUMAN RecName: Full=Transitional endoplasmic reticulum ATPase; Short=TER ATPase; AltName: Full=15S Mg(2+)-ATPase p97 subunit; AltName: Full=Valosin-containing protein; Short=VCP >gi|146291078|sp|Q01853.4|TERA_MOUSE RecName: Full=Transitional endoplasmic reticulum ATPase; Short=TER ATPase; AltName: Full=15S Mg(2+)-ATPase p97 subunit; AltName: Full=Valosin-containing protein; Short=VCP >gi|185177986|pdb|3CF1|A Chain A, Structure Of P97VCP IN COMPLEX WITH ADPADP.ALFX >gi|185177987|pdb|3CF1|B Chain B, Structure Of P97VCP IN COMPLEX WITH ADPADP.ALFX >gi|185177988|pdb|3CF1|C Chain C, Structure Of P97VCP IN COMPLEX WITH ADPADP.ALFX >gi|185177989|pdb|3CF2|A Chain A, Structure Of P97VCP IN COMPLEX WITH ADPAMP-Pnp >gi|185177990|pdb|3CF2|B Chain B, Structure Of P97VCP IN COMPLEX WITH ADPAMP-Pnp >gi|185177991|pdb|3CF2|C Chain C, Structure Of P97VCP IN COMPLEX WITH ADPAMP-Pnp >gi|185177992|pdb|3CF2|D Chain D, Structure Of P97VCP IN COMPLEX WITH ADPAMP-Pnp >gi|185177993|pdb|3CF3|A Chain A, Structure Of P97VCP IN COMPLEX WITH ADP >gi|185177994|pdb|3CF3|B Chain B, Structure Of P97VCP IN COMPLEX WITH ADP >gi|185177995|pdb|3CF3|C Chain C, Structure Of P97VCP IN COMPLEX WITH ADP >gi|2984586|gb|AAC07984.1| TERA_HUMAN [Homo sapiens] >gi|5410290|gb|AAD43016.1| transitional endoplasmic reticulum ATPase [Homo sapiens] >gi|29144873|gb|AAH43053.1| Valosin containing protein [Mus musculus] >gi|29144989|gb|AAH49114.1| Valosin containing protein [Mus musculus] >gi|83405636|gb|AAI10914.1| Valosin-containing protein [Homo sapiens] >gi|119578808|gb|EAW58404.1| valosin-containing protein, isoform CRA_b [Homo sapiens] 100 0 sp|P55072|TERA_HUMAN Transitional endoplasmic reticulum ATPase OS=Homo sapiens GN=VCP PE=1 SV=4 100 0 G3QL07 G3QL07_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=VCP PE=3 SV=1 YDL126c 1178 0 COG0464 ATPases of the AAA+ class O Posttranslational modification, protein turnover, chaperones ; K13525|1|0.0|1501|ptr:747490|transitional endoplasmic reticulum ATPase GO:0030433//ER-associated protein catabolic process;GO:0042981//regulation of apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006302//double-strand break repair;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0031334//positive regulation of protein complex assembly;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0030970//retrograde protein transport, ER to cytosol;GO:0070842//aggresome assembly;GO:0051260//protein homooligomerization;GO:0006200//ATP catabolic process;GO:0030968//endoplasmic reticulum unfolded protein response GO:0005102//receptor binding;GO:0031593//polyubiquitin binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0019903//protein phosphatase binding;GO:0008289//lipid binding;GO:0032403//protein complex binding;GO:0016887//ATPase activity;GO:0005524//ATP binding GO:0005730//nucleolus;GO:0005829//cytosol;GO:0000502//proteasome complex;GO:0035861//site of double-strand break;GO:0005783//endoplasmic reticulum 483 tr|Q6ZME7|Q6ZME7_HUMAN cDNA FLJ23972 fis, clone HEP18230, highly similar to 65 kDa FK506-binding protein (EC 5.2.1.8) OS=Homo sapiens PE=2 SV=1 64920 MFPAGPPSHSLLRLPLLQLLLLVVQAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGLAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDAVQLEALELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGARGVPGSAVLLFEVELVSREDGLPTGYLFVWHKDPPANLFEDMDLNKDGEVPPEEFSTFIKAQVSEGKGRPHAWAGP 550 15.1 2 22 22 7 7 0.785 0.827 0.98 16 16 16 * * - 0.864 0.102630405 tr|Q6ZME7|Q6ZME7_HUMAN 100 1.00E-123 gi|6453607|emb|CAB61418.1| hypothetical protein [Homo sapiens] 99.81 0 sp|Q96AY3|FKB10_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP10 OS=Homo sapiens GN=FKBP10 PE=1 SV=1 100 0 Q6ZME7 Q6ZME7_HUMAN cDNA FLJ23972 fis, clone HEP18230, highly similar to 65 kDa FK506-binding protein (EC 5.2.1.8) OS=Homo sapiens PE=2 SV=1 DR1839 100 7.00E-21 COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 O Posttranslational modification, protein turnover, chaperones ; K09575|1|0.0|1042|hsa:60681|FK506-binding protein 9/10 [EC:5.2.1.8] GO:0006457//protein folding;GO:0000413//protein peptidyl-prolyl isomerization GO:0005528//FK506 binding;GO:0005509//calcium ion binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane 484 tr|A0A087WXE9|A0A087WXE9_HUMAN Inactive serine protease PAMR1 OS=Homo sapiens GN=PAMR1 PE=3 SV=1 88932 MCRECCEYDQIECVCPGKREVVGYTIPCCRNEENECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRAPKGQILLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEERNCSDPGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICIKACREPKISDLVRRRVLPMQVQSRETPLHQLYSAAFSKQKLQSAPTKKPALPFGDLPMGYQHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIENITAPKTQGLRWPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICLAASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVSVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRLSTAFTKVLPFKDWIERNMK 82 5.9 3 3 3 3 3 0.902 0.764 0.96 2 2 2 - - - 0.875333333 0.100684325 tr|A0A087WXE9|A0A087WXE9_HUMAN 100 0 gi|50659100|ref|NP_001001991.1| inactive serine protease PAMR1 isoform b precursor [Homo sapiens] >gi|74738221|sp|Q6UXH9.1|PAMR1_HUMAN RecName: Full=Inactive serine protease PAMR1; AltName: Full=Peptidase domain-containing protein associated with muscle regeneration 1; AltName: Full=Regeneration-associated muscle protease homolog; Flags: Precursor >gi|37181817|gb|AAQ88712.1| ELGC699 [Homo sapiens] 100 0 sp|Q6UXH9|PAMR1_HUMAN Inactive serine protease PAMR1 OS=Homo sapiens GN=PAMR1 PE=1 SV=1 100 0 A8MQ58 A8MQ58_HUMAN Inactive serine protease PAMR1 OS=Homo sapiens GN=PAMR1 PE=3 SV=3 VC1200 68.2 5.00E-11 COG5640 Secreted trypsin-like serine protease O Posttranslational modification, protein turnover, chaperones ; K03992|1|2e-39|164|bfo:BRAFLDRAFT_91518|mannan-binding lectin serine protease 1 [EC:3.4.21.-] GO:0006508//proteolysis GO:0004252//serine-type endopeptidase activity GO:0005576//extracellular region 485 sp|P12814|ACTN1_HUMAN Alpha-actinin-1 OS=Homo sapiens GN=ACTN1 PE=1 SV=2 >tr|A0A024R694|A0A024R694_HUMAN Actinin, alpha 1, isoform CRA_a OS=Homo sapiens GN=ACTN1 PE=4 SV=1 120294 MDHYDSQQTNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQVEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITMDELRRELPPDQAEYCIARMAPYTGPDSVPGALDYMSFSTALYGESDL 5560 44.8 - 277 187 34 22 0.652 0.527 0.514 143 147 144 * * * 0.564333333 0.0761993 sp|P12814|ACTN1_HUMAN 100 0 gi|4501891|ref|NP_001093.1| alpha-actinin-1 isoform b [Homo sapiens] >gi|46397817|sp|P12814.2|ACTN1_HUMAN RecName: Full=Alpha-actinin-1; AltName: Full=Alpha-actinin cytoskeletal isoform; AltName: Full=F-actin cross-linking protein; AltName: Full=Non-muscle alpha-actinin-1 >gi|178052|gb|AAA51582.1| alpha-actinin [Homo sapiens] >gi|13097756|gb|AAH03576.1| Actinin, alpha 1 [Homo sapiens] >gi|16041771|gb|AAH15766.1| Actinin, alpha 1 [Homo sapiens] >gi|30583253|gb|AAP35871.1| actinin, alpha 1 [Homo sapiens] >gi|119601377|gb|EAW80971.1| actinin, alpha 1, isoform CRA_a [Homo sapiens] >gi|119601382|gb|EAW80976.1| actinin, alpha 1, isoform CRA_a [Homo sapiens] 100 0 sp|P12814|ACTN1_HUMAN Alpha-actinin-1 OS=Homo sapiens GN=ACTN1 PE=1 SV=2 100 0 H9F1Z8 H9F1Z8_MACMU Alpha-actinin-1 isoform c (Fragment) OS=Macaca mulatta GN=ACTN1 PE=2 SV=1 SPAC15A10.08 271 5.00E-72 COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) Z Cytoskeleton ; K05699|1|0.0|1863|hsa:87|actinin alpha GO:0043462//regulation of ATPase activity;GO:0030168//platelet activation;GO:0046928//regulation of neurotransmitter secretion;GO:0042981//regulation of apoptotic process;GO:0051017//actin filament bundle assembly;GO:0048041//focal adhesion assembly;GO:0002576//platelet degranulation;GO:0051271//negative regulation of cellular component movement GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0019904//protein domain specific binding;GO:0005523//tropomyosin binding;GO:0043495//protein anchor;GO:0051015//actin filament binding;GO:0017166//vinculin binding;GO:0044325//ion channel binding GO:0005925//focal adhesion;GO:0031143//pseudopodium;GO:0012506//vesicle membrane;GO:0043197//dendritic spine;GO:0031093//platelet alpha granule lumen;GO:0005576//extracellular region;GO:0005829//cytosol;GO:0001726//ruffle;GO:0001725//stress fiber;GO:0030018//Z disc;GO:0005916//fascia adherens;GO:0030864//cortical actin cytoskeleton;GO:0005634//nucleus 486 tr|B3KPW6|B3KPW6_HUMAN cDNA FLJ32365 fis, clone PUAEN1000161, highly similar to Homo sapiens CCR4-NOT transcription complex, subunit 1 (CNOT1), transcript variant 2, mRNA OS=Homo sapiens PE=2 SV=1 136696 MLLNGTPFAFVIDLAALASRREYLKLDKWLTDKIREHGEPFIQACMTFLKRRCPSILGGLAPEKDQPKSAQLPPETLATMLACLQACAGSVSQELSETILTMVANCSNVMNKARQPPPGVMPKGRPPSASSLDAISPVQIDPLAGMTSLSIGGSAAPHTQSMQGFPPNLGSAFSTPQSPAKAFPPLSTPNQTTAFSGIGGLSSQLPVGGLGTGSLTGIGTGALGLPAVNNDPFVQRKLGTSGLNQPTFQQSKMKPSDLSQVWPEANQHFSKEIDDEANSYFQRIYNHPPHPTMSVDEVLEMLQRFKDSTIKREREVFNCMLRNLFEEYRFFPQYPDKELHITACLFGGIIEKGLVTYMALGLALRYVLEALRKPFGSKMYYFGIAALDRFKNRLKDYPQYCQHLASISHFMQFPHHLQEYIEYGQQSRDPPVKMQGSITTPGSIALAQAQAQAQVPAKAPLAGQVSTMVTTSTTTTVAKTVTVTRPTGVSFKKDVPPSINTTNIDTLLVATDQTERIVEPPENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQYLVMKRVSIEPNFHSLYSNFLDTLKNLITRFFRLCTEMCVEISYRAQAEQQHNPAANPTMIRAKCYHNLDAFVRLIALLVKHSGEATNTVTKINLLNKVLGIVVGVLLQDHDVRQSEFQQLPYHRIFIMLLLELNAPEHVLETINFQTLTAFCNTFHILRPTKAPGFVYAWLELISHRIFIARMLAHTPQQKGWPMYAQLLIDLFKYLAPFLRNVELTKPMQILYKGTLRVLLVLLHDFPEFLCDYHYGFCDVIPPNCIQLRNLILSAFPRNMRLPDPFTPNLKVDMLSEINIAPRILTNFTGVMPPQFKKDLDSYLKTRSPVTFLSDLRSNLQVSNEPGNRYNLQLINALVLYVGTQAIAHIHNKGSTPSMSTITHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCTMLYLFAEANTEAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPAFKFWNHEFVHCAPEIEKLFQSVAQCCMGQKQAQQVMEGTGAS 29 0.7 3 3 3 1 1 0.601 0.539 0.717 2 2 2 * - - 0.619 0.090354856 tr|B3KPW6|B3KPW6_HUMAN 100 9.00E-30 gi|351697763|gb|EHB00682.1| CCR4-NOT transcription complex subunit 1 [Heterocephalus glaber] 100 0 sp|A5YKK6|CNOT1_HUMAN CCR4-NOT transcription complex subunit 1 OS=Homo sapiens GN=CNOT1 PE=1 SV=2 100 0 G7Q1A2 G7Q1A2_MACFA Putative uncharacterized protein OS=Macaca fascicularis GN=EGM_11797 PE=4 SV=1 SPAC20G8.06 257 1.00E-67 COG5103 Cell division control protein, negative regulator of transcription DK Cell cycle control, cell division, chromosome partitioning ; Transcription ; K12604|1|0.0|1027|pon:100444542|CCR4-NOT transcription complex subunit 1 GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006355//regulation of transcription, DNA-dependent GO:0005515//protein binding GO:0005829//cytosol;GO:0000932//cytoplasmic mRNA processing body;GO:0005778//peroxisomal membrane 487 sp|Q96FQ6|S10AG_HUMAN Protein S100-A16 OS=Homo sapiens GN=S100A16 PE=1 SV=1 15197 MSDCYTELEKAVIVLVENFYKYVSKYSLVKNKISKSSFREMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEYWTLIGGITGPIAKLIHEQEQQSSS 323 29.1 - 9 9 2 2 0.797 0.466 0.651 8 8 8 - - * 0.638 0.165882489 sp|Q96FQ6|S10AG_HUMAN 100 4.00E-53 gi|310942846|pdb|3NXA|A Chain A, X-Ray Structure Of The Apo Form Of Human S100a16 >gi|310942847|pdb|3NXA|B Chain B, X-Ray Structure Of The Apo Form Of Human S100a16 >gi|310942848|pdb|3NXA|C Chain C, X-Ray Structure Of The Apo Form Of Human S100a16 >gi|310942849|pdb|3NXA|D Chain D, X-Ray Structure Of The Apo Form Of Human S100a16 100 1.00E-55 sp|Q96FQ6|S10AG_HUMAN Protein S100-A16 OS=Homo sapiens GN=S100A16 PE=1 SV=1 99.03 3.00E-53 G7NUG9 G7NUG9_MACFA Putative uncharacterized protein OS=Macaca fascicularis GN=EGM_01115 PE=4 SV=1 - - - - - - - - GO:0051592//response to calcium ion GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005829//cytosol 488 sp|Q9Y376|CAB39_HUMAN Calcium-binding protein 39 OS=Homo sapiens GN=CAB39 PE=1 SV=1 >tr|A0A024R496|A0A024R496_HUMAN Calcium binding protein 39, isoform CRA_a OS=Homo sapiens GN=CAB39 PE=4 SV=1 50054 MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQAKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA 74 8.8 - 4 4 3 3 1.098 1.105 1.214 2 2 2 - - - 1.139 0.065046137 sp|Q9Y376|CAB39_HUMAN 100 0 gi|459358711|pdb|4FZA|A Chain A, Crystal Structure Of Mst4-mo25 Complex >gi|459358713|pdb|4FZD|A Chain A, Crystal Structure Of Mst4-mo25 Complex With Wsf Motif >gi|459358716|pdb|4FZF|A Chain A, Crystal Structure Of Mst4-mo25 Complex With Dki 100 0 sp|Q9Y376|CAB39_HUMAN Calcium-binding protein 39 OS=Homo sapiens GN=CAB39 PE=1 SV=1 100 0 G3QII1 G3QII1_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=CAB39 PE=4 SV=1 - - - - - - - K08272|1|0.0|701|bta:511451|calcium binding protein 39 GO:0007050//cell cycle arrest;GO:0008286//insulin receptor signaling pathway;GO:0051291//protein heterooligomerization;GO:0046320//regulation of fatty acid oxidation;GO:0045860//positive regulation of protein kinase activity GO:0004674//protein serine/threonine kinase activity;GO:0005509//calcium ion binding;GO:0019900//kinase binding;GO:0030295//protein kinase activator activity GO:0005829//cytosol;GO:0043234//protein complex 489 tr|B4DJI4|B4DJI4_HUMAN cDNA FLJ58065, highly similar to LIM and SH3 domain protein 1 OS=Homo sapiens PE=2 SV=1 30951 MNPNCARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNVSSCPALRHPCCPLFGPLPASLADASLADVNEASASTTPALQGGPGEELGVPRCLFSVYPQTTSTHSIFFLKGLYSVGACVLNQPPLSLTVVLFSGYRGYR 66 6.8 3 3 3 2 2 1.114 1.144 0.77 2 2 2 - * - 1.009333333 0.207810811 tr|B4DJI4|B4DJI4_HUMAN 100 3.00E-06 gi|332258524|ref|XP_003278347.1| PREDICTED: uncharacterized protein LOC100598413 [Nomascus leucogenys] 100 4.00E-11 sp|P80171|LASP1_PIG LIM and SH3 domain protein 1 (Fragment) OS=Sus scrofa GN=LASP1 PE=1 SV=1 100 4.00E-25 E9Q0N6 E9Q0N6_MOUSE LIM and SH3 domain protein 1 (Fragment) OS=Mus musculus GN=Lasp1 PE=4 SV=1 - - - - - - - K09377|1|5e-06|51.2|bfo:BRAFLDRAFT_269843|cysteine and glycine-rich protein GO:0034220//ion transmembrane transport GO:0015075//ion transmembrane transporter activity;GO:0005070//SH3/SH2 adaptor activity;GO:0051015//actin filament binding;GO:0008270//zinc ion binding GO:0005925//focal adhesion;GO:0030864//cortical actin cytoskeleton 490 tr|H0YL52|H0YL52_HUMAN Tropomyosin alpha-1 chain (Fragment) OS=Homo sapiens GN=TPM1 PE=1 SV=1 40873 XRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 1916 21.1 2 121 15 7 1 0.503 0.393 0.35 10 10 10 * * * 0.415333333 0.078907118 tr|H0YL52|H0YL52_HUMAN 100 6.00E-109 gi|339956|gb|AAA61226.1| skeletal muscle tropomyosin, partial [Homo sapiens] 99.6 3.00E-109 sp|P09493|TPM1_HUMAN Tropomyosin alpha-1 chain OS=Homo sapiens GN=TPM1 PE=1 SV=2 100 8.00E-82 H0YNC7 H0YNC7_HUMAN Tropomyosin alpha-1 chain (Fragment) OS=Homo sapiens GN=TPM1 PE=3 SV=1 - - - - - - - K10373|1|8e-109|393|mmu:22003|tropomyosin 1 GO:0034614//cellular response to reactive oxygen species;GO:0001701//in utero embryonic development;GO:0032781//positive regulation of ATPase activity;GO:0060048//cardiac muscle contraction;GO:0030336//negative regulation of cell migration;GO:0045785//positive regulation of cell adhesion;GO:0051693//actin filament capping;GO:0006937//regulation of muscle contraction;GO:0030049//muscle filament sliding;GO:0045214//sarcomere organization;GO:0031529//ruffle organization;GO:0042060//wound healing;GO:0051496//positive regulation of stress fiber assembly;GO:0003065//positive regulation of heart rate by epinephrine;GO:0055010//ventricular cardiac muscle tissue morphogenesis GO:0042803//protein homodimerization activity;GO:0047485//protein N-terminus binding;GO:0005200//structural constituent of cytoskeleton;GO:0051015//actin filament binding;GO:0008307//structural constituent of muscle GO:0032059//bleb;GO:0005862//muscle thin filament tropomyosin;GO:0005829//cytosol;GO:0031941//filamentous actin;GO:0001725//stress fiber;GO:0032587//ruffle membrane 491 sp|P48061|SDF1_HUMAN Stromal cell-derived factor 1 OS=Homo sapiens GN=CXCL12 PE=1 SV=1 14290 MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM 127 23.7 - 7 7 2 2 4.7 2.926 6.474 5 5 4 * * * 4.7 1.774 sp|P48061|SDF1_HUMAN 100 6.00E-33 gi|355562393|gb|EHH18987.1| hypothetical protein EGK_19601, partial [Macaca mulatta] 100 2.00E-42 sp|P48061|SDF1_HUMAN Stromal cell-derived factor 1 OS=Homo sapiens GN=CXCL12 PE=1 SV=1 100 3.00E-32 G7PER8 G7PER8_MACFA Putative uncharacterized protein (Fragment) OS=Macaca fascicularis GN=EGM_17942 PE=4 SV=1 - - - - - - - K10031|1|1e-42|171|pon:100173045|C-X-C motif chemokine 12 GO:0070098//chemokine-mediated signaling pathway;GO:0043434//response to peptide hormone stimulus;GO:0006955//immune response;GO:0009612//response to mechanical stimulus;GO:0008064//regulation of actin polymerization or depolymerization;GO:0001667//ameboidal cell migration;GO:0009314//response to radiation;GO:0031100//organ regeneration;GO:0033603//positive regulation of dopamine secretion;GO:0006874//cellular calcium ion homeostasis;GO:0001666//response to hypoxia;GO:0022029//telencephalon cell migration;GO:0051924//regulation of calcium ion transport;GO:0050930//induction of positive chemotaxis;GO:0009408//response to heat;GO:0008344//adult locomotory behavior;GO:0090026//positive regulation of monocyte chemotaxis;GO:0008354//germ cell migration;GO:0045666//positive regulation of neuron differentiation;GO:0001569//patterning of blood vessels;GO:0007281//germ cell development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007155//cell adhesion;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0009615//response to virus;GO:0008015//blood circulation;GO:0042098//T cell proliferation;GO:0008045//motor neuron axon guidance;GO:0001764//neuron migration;GO:0001938//positive regulation of endothelial cell proliferation;GO:2000107//negative regulation of leukocyte apoptotic process GO:0045236//CXCR chemokine receptor binding;GO:0008083//growth factor activity;GO:0008009//chemokine activity GO:0005615//extracellular space;GO:0009897//external side of plasma membrane 492 tr|A0A087WVV2|A0A087WVV2_HUMAN Ribosome-binding protein 1 OS=Homo sapiens GN=RRBP1 PE=1 SV=1 132316 MVVVPPVGAKGNTPATGTTQGKKAEGTQNQSKKAEGAPNQGRKAEGTPNQGKKTEGTPNQGKKAEGAPIQGKKADSVANQGTKVEGITNQGKKAEGSPSEGKKAEGSPNQGKKADAAANQGKKTESASVQGRNTDVAQSPEAPKQEAPAKKKSGSKKKGEPGPPDADGPLYLPYKTLVSTVGSMVFNEGEAQRLIEILSEKAGIIQDTWHKATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLLSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLEWTEAILEDEQTQRQKLTAEFEEAQTSACRLQEELEKLRTAGPLESSETEEASQLKERLEKEKKLTSDLGRAATRLQELLKTTQEQLAREKDTVKKLQEQLEKAEDGSSSKEGTSV 72 2.7 6 7 7 2 2 0.733 0.572 0.78 2 2 2 - - - 0.695 0.109082538 tr|A0A087WVV2|A0A087WVV2_HUMAN 99.79 0 gi|118764063|gb|AAI28578.1| RRBP1 protein [Homo sapiens] 98.05 0 sp|Q9P2E9|RRBP1_HUMAN Ribosome-binding protein 1 OS=Homo sapiens GN=RRBP1 PE=1 SV=4 100 0 F8W7S5 F8W7S5_HUMAN Ribosome-binding protein 1 OS=Homo sapiens GN=RRBP1 PE=4 SV=1 - - - - - - - K14000|1|0.0|1456|ptr:100613210|ribosome-binding protein 1 GO:0007165//signal transduction;GO:0006412//translation;GO:0015031//protein transport GO:0004872//receptor activity GO:0030176//integral to endoplasmic reticulum membrane;GO:0005840//ribosome 493 tr|B2RD79|B2RD79_HUMAN Ubiquitin carboxyl-terminal hydrolase OS=Homo sapiens PE=2 SV=1 70456 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSSNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ 97 7.3 3 7 7 3 3 0.993 1.306 0.79 3 3 3 - - - 1.029666667 0.259946789 tr|B2RD79|B2RD79_HUMAN 100 0 gi|189067888|dbj|BAG37826.1| unnamed protein product [Homo sapiens] 99.8 0 sp|P54578|UBP14_HUMAN Ubiquitin carboxyl-terminal hydrolase 14 OS=Homo sapiens GN=USP14 PE=1 SV=3 100 0 B2RD79 B2RD79_HUMAN Ubiquitin carboxyl-terminal hydrolase OS=Homo sapiens PE=2 SV=1 YJL197w 57 7.00E-08 COG5560 Ubiquitin C-terminal hydrolase O Posttranslational modification, protein turnover, chaperones ; K11843|1|0.0|945|ptr:455325|ubiquitin carboxyl-terminal hydrolase 14 [EC:3.1.2.15] GO:0006511//ubiquitin-dependent protein catabolic process;GO:0061136//regulation of proteasomal protein catabolic process;GO:0010951//negative regulation of endopeptidase activity;GO:0050920//regulation of chemotaxis;GO:0007268//synaptic transmission GO:0004221//ubiquitin thiolesterase activity;GO:0004866//endopeptidase inhibitor activity;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//ubiquitin-specific protease activity;GO:0070628//proteasome binding;GO:0008193//tRNA guanylyltransferase activity GO:0000502//proteasome complex;GO:0009986//cell surface;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane 494 sp|Q01995|TAGL_HUMAN Transgelin OS=Homo sapiens GN=TAGLN PE=1 SV=4 >tr|Q5U0D2|Q5U0D2_HUMAN Transgelin OS=Homo sapiens GN=TAGLN PE=2 SV=1 28129 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS 2447 56.7 - 159 159 10 10 0.408 0.369 0.338 98 109 102 * * - 0.371666667 0.035076108 sp|Q01995|TAGL_HUMAN 100 6.00E-49 gi|62088690|dbj|BAD92792.1| transgelin variant [Homo sapiens] 100 1.00E-116 sp|Q01995|TAGL_HUMAN Transgelin OS=Homo sapiens GN=TAGLN PE=1 SV=4 100 4.00E-115 G3REJ2 G3REJ2_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=TAGLN PE=4 SV=1 YOR367w 70.5 2.00E-12 COG5199 Calponin Z Cytoskeleton ; K05730|1|3e-07|55.1|dre:559145|vav oncogene GO:0007517//muscle organ development GO:0003779//actin binding GO:0005737//cytoplasm 495 tr|A0A024R0A0|A0A024R0A0_HUMAN Matrix-remodelling associated 8, isoform CRA_a OS=Homo sapiens GN=MXRA8 PE=4 SV=1 53434 MALPSRILLWKLVLLQSSAVLLHSGSWVPAAAGSSVVSESAVSWEAGARAVLRCQSPRMVWTQDRLHDRQRVLHWDLRGPGGGPARRLLDLYSAGEQRVYEARDRGRLELSASAFDDGNFSLLIRAVEETDAGLYTCNLHHHYCHLYESLAVRLEVTDGPPATPAYWDGEKEVLAVARGAPALLTCVNRGHVWTDRHVEEAQQVVHWDRQPPGVPHDRADRLLDLYASGERRAYGPLFLRDRVAVGADAFERGDFSLRIEPLEVADEGTYSCHLHHHYCGLHERRVFHLTVAEPHAEPPPRGSPGNGSSHSGAPGPDPTLARGHNVINVIVPESRAHFFQQLGYVLATLLLFILLLVTVLLAARRRRGGYEYSDQKSGKSKGKDVNLAEFAVAAGDQMLYRSEDIQLASSPPTDYKNNILKERAELAHSPLPAKYIDLDKDPSGLCPLGA 254 14.4 2 16 16 6 6 0.976 1.276 1.016 13 13 13 - * - 1.089333333 0.162890556 tr|A0A024R0A0|A0A024R0A0_HUMAN 100 0 gi|119576624|gb|EAW56220.1| matrix-remodelling associated 8, isoform CRA_a [Homo sapiens] >gi|119576625|gb|EAW56221.1| matrix-remodelling associated 8, isoform CRA_a [Homo sapiens] 98.41 0 sp|Q9BRK3|MXRA8_HUMAN Matrix-remodeling-associated protein 8 OS=Homo sapiens GN=MXRA8 PE=1 SV=1 98.76 0 G1QGP8 G1QGP8_NOMLE Uncharacterized protein (Fragment) OS=Nomascus leucogenys GN=MXRA8 PE=4 SV=1 - - - - - - - - - - GO:0016021//integral to membrane 496 sp|P14618|KPYM_HUMAN Pyruvate kinase PKM OS=Homo sapiens GN=PKM PE=1 SV=4 >tr|V9HWB8|V9HWB8_HUMAN Pyruvate kinase OS=Homo sapiens GN=HEL-S-30 PE=2 SV=1 70030 MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 4756 49.9 - 183 36 22 4 0.709 0.535 0.55 27 31 26 * - - 0.598 0.096420952 sp|P14618|KPYM_HUMAN 100 0 gi|404312785|pdb|3U2Z|A Chain A, Activator-Bound Structure Of Human Pyruvate Kinase M2 >gi|404312786|pdb|3U2Z|B Chain B, Activator-Bound Structure Of Human Pyruvate Kinase M2 >gi|404312787|pdb|3U2Z|C Chain C, Activator-Bound Structure Of Human Pyruvate Kinase M2 >gi|404312788|pdb|3U2Z|D Chain D, Activator-Bound Structure Of Human Pyruvate Kinase M2 100 0 sp|P14618|KPYM_HUMAN Pyruvate kinase isozymes M1/M2 OS=Homo sapiens GN=PKM2 PE=1 SV=4 100 8.00E-16 F7BB50 F7BB50_CALJA Pyruvate kinase OS=Callithrix jacchus GN=LOC100412392 PE=3 SV=1 SPAC4H3.10c 518 9.00E-147 COG0469 Pyruvate kinase G Carbohydrate transport and metabolism ; K00873|1|0.0|1095|mcc:697742|pyruvate kinase [EC:2.7.1.40] GO:0044281//small molecule metabolic process;GO:0006096//glycolysis;GO:0012501//programmed cell death GO:0004743//pyruvate kinase activity;GO:0005515//protein binding;GO:0030955//potassium ion binding;GO:0005524//ATP binding;GO:0000287//magnesium ion binding GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion 497 tr|H0Y5E4|H0Y5E4_HUMAN CD44 antigen (Fragment) OS=Homo sapiens GN=CD44 PE=1 SV=1 34316 XDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATRDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRS 372 10.5 6 24 24 3 3 0.949 0.845 0.945 16 16 16 - - - 0.913 0.058923679 tr|H0Y5E4|H0Y5E4_HUMAN 100 8.00E-134 gi|48255941|ref|NP_001001391.1| CD44 antigen isoform 4 precursor [Homo sapiens] >gi|950420|gb|AAB13624.1| cell surface glycoprotein CD44 [Homo sapiens] >gi|119588550|gb|EAW68144.1| CD44 antigen (Indian blood group), isoform CRA_a [Homo sapiens] 100 4.00E-119 sp|P16070|CD44_HUMAN CD44 antigen OS=Homo sapiens GN=CD44 PE=1 SV=3 100 4.00E-74 H0YD17 H0YD17_HUMAN CD44 antigen (Fragment) OS=Homo sapiens GN=CD44 PE=4 SV=1 - - - - - - - K06256|1|3e-119|428|pon:100172786|CD44 antigen GO:1900625//positive regulation of monocyte aggregation;GO:0010628//positive regulation of gene expression;GO:0007160//cell-matrix adhesion;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0043066//negative regulation of apoptotic process;GO:0016055//Wnt receptor signaling pathway;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0051216//cartilage development;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0030214//hyaluronan catabolic process;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0060442//branching involved in prostate gland morphogenesis;GO:0005975//carbohydrate metabolic process;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0044281//small molecule metabolic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0002246//wound healing involved in inflammatory response GO:0005540//hyaluronic acid binding;GO:0004415//hyalurononglucosaminidase activity;GO:0005518//collagen binding;GO:0004888//transmembrane signaling receptor activity GO:0016323//basolateral plasma membrane;GO:0005794//Golgi apparatus;GO:0009897//external side of plasma membrane;GO:0005887//integral to plasma membrane 498 tr|B4DI19|B4DI19_HUMAN cDNA FLJ59524, highly similar to Cysteinyl-tRNA synthetase (EC 6.1.1.16) OS=Homo sapiens PE=2 SV=1 93853 MGHARSYISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENVSMVCPHMTWRAKSSAKGKPRS 56 6 6 5 5 4 4 0.778 1.103 1.079 2 2 2 - - - 0.986666667 0.181108623 tr|B4DI19|B4DI19_HUMAN 100 0 gi|21269877|ref|NP_644802.1| cysteine--tRNA ligase, cytoplasmic isoform a [Homo sapiens] >gi|9837517|gb|AAG00579.1|AF288207_1 cysteinyl-tRNA synthetase [Homo sapiens] >gi|119622943|gb|EAX02538.1| cysteinyl-tRNA synthetase, isoform CRA_c [Homo sapiens] 100 0 sp|P49589|SYCC_HUMAN Cysteine--tRNA ligase, cytoplasmic OS=Homo sapiens GN=CARS PE=1 SV=3 100 0 B4DI19 B4DI19_HUMAN cDNA FLJ59524, highly similar to Cysteinyl-tRNA synthetase (EC 6.1.1.16) OS=Homo sapiens PE=2 SV=1 YNL247w 506 6.00E-143 COG0215 Cysteinyl-tRNA synthetase J Translation, ribosomal structure and biogenesis ; K01883|1|0.0|1256|hsa:833|cysteinyl-tRNA synthetase [EC:6.1.1.16] GO:0006423//cysteinyl-tRNA aminoacylation GO:0008270//zinc ion binding;GO:0004817//cysteine-tRNA ligase activity;GO:0005524//ATP binding;GO:0000049//tRNA binding;GO:0042803//protein homodimerization activity GO:0005829//cytosol 499 sp|P55268|LAMB2_HUMAN Laminin subunit beta-2 OS=Homo sapiens GN=LAMB2 PE=1 SV=2 >tr|A0A024R319|A0A024R319_HUMAN Laminin, beta 2 (Laminin S), isoform CRA_a OS=Homo sapiens GN=LAMB2 PE=4 SV=1 213325 MELTSRERGRGQPLPWELRLGLLLSVLAATLAQAPAPDVPGCSRGSCYPATGDLLVGRADRLTASSTCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQSENGIPAVTIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLLKITNLRVNLTRLHTLGDNLLDPRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFRPFLDHLIWEAEDTRGQVLDVVERLVTPGETPSWTGSGFVRLQEGQTLEFLVASVPKAMDYDLLLRLEPQVPEQWAELELIVQRPGPVPAHSLCGHLVPKDDRIQGTLQPHARYLIFPNPVCLEPGISYKLHLKLVRTGGSAQPETPYSGPGLLIDSLVLLPRVLVLEMFSGGDAAALERQATFERYQCHEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFESSFWHMQEKLGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRSVLQAINLQVQIYNTCQ 301 7.2 - 27 27 10 10 1.221 1.138 1.613 11 11 11 - - - 1.324 0.25369864 sp|P55268|LAMB2_HUMAN 100 0 gi|119703755|ref|NP_002283.3| laminin subunit beta-2 precursor [Homo sapiens] >gi|156630892|sp|P55268.2|LAMB2_HUMAN RecName: Full=Laminin subunit beta-2; AltName: Full=Laminin B1s chain; AltName: Full=Laminin-11 subunit beta; AltName: Full=Laminin-14 subunit beta; AltName: Full=Laminin-15 subunit beta; AltName: Full=Laminin-3 subunit beta; AltName: Full=Laminin-4 subunit beta; AltName: Full=Laminin-7 subunit beta; AltName: Full=Laminin-9 subunit beta; AltName: Full=S-laminin subunit beta; Short=S-LAM beta; Flags: Precursor >gi|119585362|gb|EAW64958.1| laminin, beta 2 (laminin S), isoform CRA_a [Homo sapiens] >gi|119585363|gb|EAW64959.1| laminin, beta 2 (laminin S), isoform CRA_a [Homo sapiens] 100 0 sp|P55268|LAMB2_HUMAN Laminin subunit beta-2 OS=Homo sapiens GN=LAMB2 PE=1 SV=2 99.67 0 Q15483 Q15483_HUMAN S-laminin (Fragment) OS=Homo sapiens PE=2 SV=1 NMA0386 58.5 1.00E-07 COG1322 Uncharacterized protein conserved in bacteria S Function unknown ; K06243|1|0.0|3378|hsa:3913|laminin, beta 2 GO:0007411//axon guidance;GO:0007492//endoderm development;GO:0014044//Schwann cell development;GO:0031581//hemidesmosome assembly;GO:0022617//extracellular matrix disassembly;GO:0006461//protein complex assembly;GO:0034446//substrate adhesion-dependent cell spreading;GO:0007528//neuromuscular junction development;GO:0060041//retina development in camera-type eye;GO:0007601//visual perception;GO:0048677//axon extension involved in regeneration;GO:0050679//positive regulation of epithelial cell proliferation;GO:0072249//metanephric glomerular visceral epithelial cell development;GO:0014002//astrocyte development;GO:0016477//cell migration;GO:0072274//metanephric glomerular basement membrane development GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0043208//glycosphingolipid binding GO:0043259//laminin-10 complex;GO:0005608//laminin-3 complex;GO:0005615//extracellular space;GO:0043260//laminin-11 complex;GO:0005606//laminin-1 complex 500 tr|B5BUI8|B5BUI8_HUMAN Dual specificity phosphatase 3 (Fragment) OS=Homo sapiens GN=DUSP3 PE=2 SV=1 24139 MSGSFELSVQDLNDLLSDGSRCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP 56 13.5 2 2 2 2 2 0.804 0.513 0.307 2 2 2 - - - 0.541333333 0.249708497 tr|B5BUI8|B5BUI8_HUMAN 100 3.00E-88 gi|355568745|gb|EHH25026.1| Dual specificity protein phosphatase 3, partial [Macaca mulatta] 99.46 6.00E-106 sp|P51452|DUS3_HUMAN Dual specificity protein phosphatase 3 OS=Homo sapiens GN=DUSP3 PE=1 SV=1 100 4.00E-79 H2RGD0 H2RGD0_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000108861 PE=4 SV=1 SPBC17A3.06 77 2.00E-14 COG2453 Predicted protein-tyrosine phosphatase T Signal transduction mechanisms ; K04459|1|6e-106|382|mcc:713686|dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008063//Toll signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0050868//negative regulation of T cell activation;GO:0045931//positive regulation of mitotic cell cycle;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0034134//toll-like receptor 2 signaling pathway;GO:0046329//negative regulation of JNK cascade;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0000188//inactivation of MAPK activity;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034130//toll-like receptor 1 signaling pathway;GO:0001701//in utero embryonic development GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0033549//MAP kinase phosphatase activity;GO:0004725//protein tyrosine phosphatase activity GO:0005654//nucleoplasm;GO:0001772//immunological synapse;GO:0005829//cytosol 501 sp|P06727|APOA4_HUMAN Apolipoprotein A-IV OS=Homo sapiens GN=APOA4 PE=1 SV=3 54193 MFLKAVVLTLALVAVAGARAEVSADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEVNTYAGDLQKKLVPFATELHERLAKDSEKLKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLRTQVNTQAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKVNSFFSTFKEKESQDKTLSLPELEQQQEQQQEQQQEQVQMLAPLES 854 41.4 - 46 46 16 16 0.771 2.687 0.905 30 25 21 * - - 1.454333333 1.069621117 sp|P06727|APOA4_HUMAN 100 4.00E-144 gi|387766087|pdb|3S84|A Chain A, Dimeric Apoa-Iv >gi|387766088|pdb|3S84|B Chain B, Dimeric Apoa-Iv 100 0 sp|P06727|APOA4_HUMAN Apolipoprotein A-IV OS=Homo sapiens GN=APOA4 PE=1 SV=3 98.9 4.00E-33 Q28857 Q28857_PANTR Apolipoprotein A-IV (Fragment) OS=Pan troglodytes GN=APOA4 PE=4 SV=1 - - - - - - - K08760|1|0.0|681|hsa:337|apolipoprotein A-IV GO:0042744//hydrogen peroxide catabolic process;GO:0034378//chylomicron assembly;GO:0035634//response to stilbenoid;GO:0033344//cholesterol efflux;GO:0046470//phosphatidylcholine metabolic process;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0034371//chylomicron remodeling;GO:0030300//regulation of intestinal cholesterol absorption;GO:0043691//reverse cholesterol transport;GO:0007159//leukocyte cell-cell adhesion;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0034375//high-density lipoprotein particle remodeling;GO:0042632//cholesterol homeostasis;GO:0019430//removal of superoxide radicals;GO:0010898//positive regulation of triglyceride catabolic process;GO:0044240//multicellular organismal lipid catabolic process;GO:0034445//negative regulation of plasma lipoprotein particle oxidation;GO:0006982//response to lipid hydroperoxide;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0010873//positive regulation of cholesterol esterification;GO:0002227//innate immune response in mucosa;GO:0033700//phospholipid efflux GO:0042803//protein homodimerization activity;GO:0016209//antioxidant activity;GO:0005507//copper ion binding;GO:0031210//phosphatidylcholine binding;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0043499//eukaryotic cell surface binding;GO:0017127//cholesterol transporter activity GO:0009986//cell surface;GO:0034364//high-density lipoprotein particle;GO:0042627//chylomicron;GO:0005788//endoplasmic reticulum lumen;GO:0034361//very-low-density lipoprotein particle;GO:0005813//centrosome 502 tr|I3L397|I3L397_HUMAN Eukaryotic translation initiation factor 5A-1 (Fragment) OS=Homo sapiens GN=EIF5A PE=1 SV=3 19987 MADDLDFETGDAGASATFPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDFQLIGIQDGYLSLLQDSGEVREDLRLPEGDLGKEIEQKYDCGEEILITVLSAMTEEAAV 314 16.3 2 15 15 2 2 0.887 0.594 0.981 11 11 11 - * - 0.820666667 0.201847302 tr|I3L397|I3L397_HUMAN 100 3.00E-82 gi|281352188|gb|EFB27772.1| hypothetical protein PANDA_013848 [Ailuropoda melanoleuca] 100 5.00E-83 sp|P63241|IF5A1_HUMAN Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens GN=EIF5A PE=1 SV=2 100 2.00E-81 G1MDS6 G1MDS6_AILME Uncharacterized protein OS=Ailuropoda melanoleuca PE=4 SV=1 SPAC26H5.10c 216 1.00E-56 COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) J Translation, ribosomal structure and biogenesis ; K03263|1|1e-84|311|ptr:750603|translation initiation factor 5A GO:0006413//translational initiation;GO:0043066//negative regulation of apoptotic process;GO:0006406//mRNA export from nucleus;GO:0007568//aging;GO:0006611//protein export from nucleus;GO:0006452//translational frameshifting;GO:0008284//positive regulation of cell proliferation;GO:0008612//peptidyl-lysine modification to hypusine;GO:0006917//induction of apoptosis;GO:0045905//positive regulation of translational termination;GO:0051149//positive regulation of muscle cell differentiation;GO:0045901//positive regulation of translational elongation;GO:0043687//post-translational protein modification GO:0003746//translation elongation factor activity;GO:0047485//protein N-terminus binding;GO:0003743//translation initiation factor activity;GO:0043022//ribosome binding;GO:0017070//U6 snRNA binding GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005643//nuclear pore;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0005642//annulate lamellae 503 tr|Q59GM9|Q59GM9_HUMAN Alpha-1,4 glucan phosphorylase (Fragment) OS=Homo sapiens PE=2 SV=1 116848 IPAFACAAAFLLHLFSSASAGAMAKPLTDSEKRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVASTLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLANTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNIPRD 137 9.9 1 10 7 8 6 0.802 0.543 0.651 4 4 3 - * * 0.665333333 0.130093556 tr|Q59GM9|Q59GM9_HUMAN 100 0 gi|62087740|dbj|BAD92317.1| brain glycogen phosphorylase variant [Homo sapiens] 99.76 0 sp|P11216|PYGB_HUMAN Glycogen phosphorylase, brain form OS=Homo sapiens GN=PYGB PE=1 SV=5 100 5.00E-11 G7PH60 G7PH60_MACFA Phosphorylase OS=Macaca fascicularis GN=EGM_02405 PE=3 SV=1 CPn0307 872 0 COG0058 Glucan phosphorylase G Carbohydrate transport and metabolism ; K00688|1|0.0|1692|hsa:5834|starch phosphorylase [EC:2.4.1.1] GO:0005980//glycogen catabolic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process GO:0008184//glycogen phosphorylase activity;GO:0030170//pyridoxal phosphate binding;GO:0030246//carbohydrate binding;GO:0008144//drug binding;GO:0042803//protein homodimerization activity GO:0005737//cytoplasm;GO:0030424//axon 504 tr|A8KA83|A8KA83_HUMAN cDNA FLJ78586, highly similar to Homo sapiens VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa (VAPA), mRNA OS=Homo sapiens PE=2 SV=1 34829 MAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDELMDSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEECKRLQGEMMKLSEENRHLRDEGLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL 88 10.7 1 5 3 2 1 0.915 1.065 0.698 3 3 3 - - - 0.892666667 0.184516485 tr|A8KA83|A8KA83_HUMAN 100 7.00E-109 gi|119621995|gb|EAX01590.1| VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa, isoform CRA_a [Homo sapiens] 100 2.00E-131 sp|Q5R601|VAPA_PONAB Vesicle-associated membrane protein-associated protein A OS=Pongo abelii GN=VAPA PE=2 SV=2 100 6.00E-130 H2QE89 H2QE89_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000101558 PE=4 SV=1 SPAC17C9.12 91.7 1.00E-18 COG5066 VAMP-associated protein involved in inositol metabolism U Intracellular trafficking, secretion, and vesicular transport ; K06096|1|5e-131|466|pon:100173641|vesicle-associated membrane protein-associated protein A GO:0006644//phospholipid metabolic process;GO:0070972//protein localization to endoplasmic reticulum;GO:0008219//cell death;GO:0031175//neuron projection development;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB cascade;GO:0030148//sphingolipid biosynthetic process;GO:0006944//cellular membrane fusion;GO:0044281//small molecule metabolic process GO:0004871//signal transducer activity;GO:0046982//protein heterodimerization activity;GO:0005198//structural molecule activity GO:0005923//tight junction;GO:0016021//integral to membrane;GO:0005874//microtubule;GO:0031982//vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane 505 sp|P27816|MAP4_HUMAN Microtubule-associated protein 4 OS=Homo sapiens GN=MAP4 PE=1 SV=3 156122 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNSESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI 340 6.2 1 16 16 5 5 0.829 0.773 0.707 14 14 14 * * * 0.769666667 0.061068268 sp|P27816|MAP4_HUMAN 100 0 gi|47519639|ref|NP_002366.2| microtubule-associated protein 4 isoform 1 [Homo sapiens] >gi|269849673|sp|P27816.3|MAP4_HUMAN RecName: Full=Microtubule-associated protein 4; Short=MAP-4 100 0 sp|P27816|MAP4_HUMAN Microtubule-associated protein 4 OS=Homo sapiens GN=MAP4 PE=1 SV=3 100 0 Q05D06 Q05D06_HUMAN MAP4 protein (Fragment) OS=Homo sapiens GN=MAP4 PE=2 SV=1 - - - - - - - K10431|1|0.0|1988|ptr:460339|microtubule-associated protein 4 - GO:0015631//tubulin binding;GO:0005198//structural molecule activity GO:0005875//microtubule associated complex;GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0005886//plasma membrane 506 tr|B5BU38|B5BU38_HUMAN Annexin OS=Homo sapiens GN=ANXA1 PE=2 SV=1 48923 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQLDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 308 23.1 1 13 13 5 5 1.167 0.714 0.799 9 9 9 - * - 0.893333333 0.240782751 tr|B5BU38|B5BU38_HUMAN 100 2.00E-87 gi|194384442|dbj|BAG59381.1| unnamed protein product [Homo sapiens] 99.71 0 sp|P04083|ANXA1_HUMAN Annexin A1 OS=Homo sapiens GN=ANXA1 PE=1 SV=2 100 0 B5BU38 B5BU38_HUMAN Annexin OS=Homo sapiens GN=ANXA1 PE=2 SV=1 - - - - - - - - GO:0043065//positive regulation of apoptotic process;GO:0031340//positive regulation of vesicle fusion;GO:0070555//response to interleukin-1;GO:0010165//response to X-ray;GO:0043434//response to peptide hormone stimulus;GO:0097350//neutrophil clearance;GO:0031394//positive regulation of prostaglandin biosynthetic process;GO:0060206//estrous cycle phase;GO:0014070//response to organic cyclic compound;GO:0018149//peptide cross-linking;GO:0030073//insulin secretion;GO:0070301//cellular response to hydrogen peroxide;GO:0050482//arachidonic acid secretion;GO:0042127//regulation of cell proliferation;GO:0031018//endocrine pancreas development;GO:0030216//keratinocyte differentiation;GO:0002674//negative regulation of acute inflammatory response;GO:0071385//cellular response to glucocorticoid stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0050709//negative regulation of protein secretion;GO:0007049//cell cycle;GO:0070365//hepatocyte differentiation;GO:0006928//cellular component movement;GO:0046632//alpha-beta T cell differentiation;GO:0032355//response to estradiol stimulus;GO:0042493//response to drug;GO:0042063//gliogenesis GO:0042803//protein homodimerization activity;GO:0003697//single-stranded DNA binding;GO:0005198//structural molecule activity;GO:0005102//receptor binding;GO:0005544//calcium-dependent phospholipid binding;GO:0003727//single-stranded RNA binding;GO:0030674//protein binding, bridging;GO:0005509//calcium ion binding;GO:0019834//phospholipase A2 inhibitor activity GO:0043234//protein complex;GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0031966//mitochondrial membrane;GO:0042383//sarcolemma;GO:0005929//cilium;GO:0001533//cornified envelope;GO:0005634//nucleus 507 tr|Q6P6D7|Q6P6D7_HUMAN Phosphoglycerate mutase 1 (Brain) OS=Homo sapiens GN=PGAM1 PE=2 SV=1 34696 MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLLVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKAKK 816 31.1 2 29 29 6 6 0.863 0.796 0.64 27 27 27 * * * 0.766333333 0.114421735 tr|Q6P6D7|Q6P6D7_HUMAN 100 2.00E-140 gi|38566176|gb|AAH62302.1| Phosphoglycerate mutase 1 (brain) [Homo sapiens] 99.61 2.00E-140 sp|P18669|PGAM1_HUMAN Phosphoglycerate mutase 1 OS=Homo sapiens GN=PGAM1 PE=1 SV=2 100 6.00E-140 Q6P6D7 Q6P6D7_HUMAN Phosphoglycerate mutase OS=Homo sapiens GN=PGAM1 PE=2 SV=1 gpmA 298 6.00E-81 COG0588 Phosphoglycerate mutase 1 G Carbohydrate transport and metabolism ; K01834|1|1e-140|498|ssc:100154776|2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.1] GO:0045730//respiratory burst;GO:0043456//regulation of pentose-phosphate shunt;GO:0006094//gluconeogenesis;GO:0006110//regulation of glycolysis GO:0046538//2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity;GO:0019901//protein kinase binding;GO:0004082//bisphosphoglycerate mutase activity;GO:0004083//bisphosphoglycerate 2-phosphatase activity GO:0005829//cytosol;GO:0005634//nucleus 508 sp|P04080|CYTB_HUMAN Cystatin-B OS=Homo sapiens GN=CSTB PE=1 SV=2 >tr|Q76LA1|Q76LA1_HUMAN CSTB protein OS=Homo sapiens GN=CSTB PE=2 SV=1 14232 MMCGAPSATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF 720 33.7 - 23 23 3 3 0.814 0.644 0.677 21 21 21 * * * 0.711666667 0.090146178 sp|P04080|CYTB_HUMAN 100 4.00E-52 gi|4503117|ref|NP_000091.1| cystatin-B [Homo sapiens] >gi|1706278|sp|P04080.2|CYTB_HUMAN RecName: Full=Cystatin-B; AltName: Full=CPI-B; AltName: Full=Liver thiol proteinase inhibitor; AltName: Full=Stefin-B >gi|45476793|sp|P60575.1|CYTB_PANPA RecName: Full=Cystatin-B; AltName: Full=Stefin-B >gi|45476794|sp|P60576.1|CYTB_PONPY RecName: Full=Cystatin-B; AltName: Full=Stefin-B >gi|52000705|sp|Q76LA0.1|CYTB_GORGO RecName: Full=Cystatin-B; AltName: Full=Stefin-B >gi|7263012|gb|AAF44059.1|AF208234_1 cystatin B [Homo sapiens] >gi|291927|gb|AAA35727.1| cystatin B [Homo sapiens] >gi|1235678|gb|AAA99014.1| cystatin B [Homo sapiens] >gi|7768760|dbj|BAA95541.1| cystatin B (liver thiol proteinase inhibitor) [Homo sapiens] >gi|13097210|gb|AAH03370.1| Cystatin B (stefin B) [Homo sapiens] >gi|14714769|gb|AAH10532.1| Cystatin B (stefin B) [Homo sapiens] >gi|23496466|dbj|BAC20304.1| cystatin B [Homo sapiens] >gi|23496470|dbj|BAC20306.1| cystatin B [Pan paniscus] >gi|23496472|dbj|BAC20307.1| cystatin B [Gorilla gorilla] >gi|23496474|dbj|BAC20308.1| cystatin B [Pongo pygmaeus] >gi|30582919|gb|AAP35689.1| cystatin B (stefin B) [Homo sapiens] >gi|49457292|emb|CAG46945.1| CSTB [Homo sapiens] >gi|119629878|gb|EAX09473.1| cystatin B (stefin B), isoform CRA_a [Homo sapiens] >gi|119629879|gb|EAX09474.1| cystatin B (stefin B), isoform CRA_a [Homo sapiens] 100 5.00E-53 sp|Q76LA0|CYTB_GORGO Cystatin-B OS=Gorilla gorilla gorilla GN=CSTB PE=3 SV=1 100 2.00E-51 Q76LA1 Q76LA1_HUMAN CSTB protein OS=Homo sapiens GN=CSTB PE=2 SV=1 - - - - - - - K13907|1|4e-53|206|pon:100433135|cystatin-A/B GO:0010951//negative regulation of endopeptidase activity;GO:0042981//regulation of apoptotic process;GO:0008344//adult locomotory behavior GO:0002020//protease binding;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0005737//cytoplasm;GO:0005730//nucleolus 509 tr|H6VRF8|H6VRF8_HUMAN Keratin 1 OS=Homo sapiens GN=KRT1 PE=3 SV=1 75006 MSRQFTSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSGVTR 283 8.9 5 13 5 5 1 0.892 0.878 0.561 3 3 3 - - - 0.777 0.187192414 tr|H6VRF8|H6VRF8_HUMAN 100 0 gi|375314771|gb|AFA52002.1| keratin 1 [Homo sapiens] 99.8 0 sp|P04264|K2C1_HUMAN Keratin, type II cytoskeletal 1 OS=Homo sapiens GN=KRT1 PE=1 SV=6 100 0 H6VRF8 H6VRF8_HUMAN Keratin 1 OS=Homo sapiens GN=KRT1 PE=3 SV=1 SPAC4A8.05c 63.5 1.00E-09 COG5022 Myosin heavy chain Z Cytoskeleton ; K07605|1|0.0|779|hsa:3848|type II keratin, basic GO:0006979//response to oxidative stress;GO:0042730//fibrinolysis;GO:0008544//epidermis development;GO:0045765//regulation of angiogenesis;GO:0001867//complement activation, lectin pathway GO:0004872//receptor activity;GO:0005515//protein binding;GO:0005200//structural constituent of cytoskeleton;GO:0030246//carbohydrate binding GO:0045095//keratin filament;GO:0005886//plasma membrane 510 tr|C9IZG4|C9IZG4_HUMAN Protein CutA OS=Homo sapiens GN=CUTA PE=1 SV=1 16806 MPALLPVASRLLLLPRVLLTMASGSPPTQPSPASDSGSGYVPGSVSAAFVTCPNEKVAKEIARAVVEKRLAACVNLIPQITSIYEWKGKIEEDSEVLMMIKTQSSLVPALTDFVRSVHPYEVAESCHDEPCSCSS 119 25.2 1 7 7 4 4 0.405 1.052 0.62 3 3 3 - - - 0.692333333 0.329509231 tr|C9IZG4|C9IZG4_HUMAN 100 4.00E-49 gi|119624137|gb|EAX03732.1| cutA divalent cation tolerance homolog (E. coli), isoform CRA_b [Homo sapiens] 100 1.00E-55 sp|O60888|CUTA_HUMAN Protein CutA OS=Homo sapiens GN=CUTA PE=1 SV=2 100 6.00E-54 G3QDE6 G3QDE6_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=CUTA PE=4 SV=1 DR2294 81.3 4.00E-16 COG1324 Uncharacterized protein involved in tolerance to divalent cations P Inorganic ion transport and metabolism ; K03926|1|3e-62|236|ptr:746949|periplasmic divalent cation tolerance protein GO:0051260//protein homooligomerization;GO:0008104//protein localization;GO:0010038//response to metal ion GO:0019899//enzyme binding GO:0016020//membrane 511 tr|B2RD14|B2RD14_HUMAN Ubiquitin carboxyl-terminal hydrolase OS=Homo sapiens PE=2 SV=1 30338 MQLKPMEINPEMLNKVLYRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPSPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA 477 24.2 1 29 29 5 5 0.445 0.395 0.464 12 13 12 * * * 0.434666667 0.035641736 tr|B2RD14|B2RD14_HUMAN 100 2.00E-119 gi|189067502|dbj|BAG37761.1| unnamed protein product [Homo sapiens] 99.1 2.00E-118 sp|P09936|UCHL1_HUMAN Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Homo sapiens GN=UCHL1 PE=1 SV=2 100 6.00E-119 B2RD14 B2RD14_HUMAN cDNA, FLJ96414, highly similar to Homo sapiens ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1), mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K05611|1|2e-118|424|hsa:7345|ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12] GO:0007412//axon target recognition;GO:0016579//protein deubiquitination;GO:0042755//eating behavior;GO:0043407//negative regulation of MAP kinase activity;GO:0008283//cell proliferation;GO:0048747//muscle fiber development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007628//adult walking behavior;GO:0008219//cell death;GO:0019233//sensory perception of pain;GO:0006950//response to stress;GO:0019896//axon transport of mitochondrion;GO:0050905//neuromuscular process GO:0004197//cysteine-type endopeptidase activity;GO:0016874//ligase activity;GO:0043130//ubiquitin binding;GO:0004221//ubiquitin thiolesterase activity;GO:0008242//omega peptidase activity;GO:0031694//alpha-2A adrenergic receptor binding GO:0005789//endoplasmic reticulum membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0043025//neuronal cell body;GO:0030424//axon;GO:0005886//plasma membrane 512 tr|Q4W4Y1|Q4W4Y1_HUMAN Dopamine receptor interacting protein 4 OS=Homo sapiens GN=DRIP4 PE=2 SV=1 116116 MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKEVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVKDFSDKINRALTAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLFEKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQSILTKSRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKERWQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIPSANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPTPAYQSLPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ 158 6.8 1 9 9 5 5 0.933 0.732 0.599 7 7 7 - - * 0.754666667 0.168149735 tr|Q4W4Y1|Q4W4Y1_HUMAN 100 1.00E-10 gi|350591042|ref|XP_003132145.3| PREDICTED: programmed cell death 6-interacting protein [Sus scrofa] 100 1.00E-11 sp|Q9WU78|PDC6I_MOUSE Programmed cell death 6-interacting protein OS=Mus musculus GN=Pdcd6ip PE=1 SV=3 100 4.00E-10 F1RRD6 F1RRD6_PIG Uncharacterized protein (Fragment) OS=Sus scrofa GN=PDCD6IP PE=4 SV=1 - - - - - - - K12200|1|0.0|1494|ptr:470783|programmed cell death 6-interacting protein GO:0007049//cell cycle;GO:0019048//virus-host interaction;GO:0006915//apoptotic process;GO:0051301//cell division;GO:0015031//protein transport GO:0046983//protein dimerization activity;GO:0048306//calcium-dependent protein binding;GO:0017124//SH3 domain binding GO:0005815//microtubule organizing center;GO:0042470//melanosome;GO:0005829//cytosol 513 tr|A6XNE2|A6XNE2_HUMAN Complement factor D preproprotein OS=Homo sapiens PE=2 SV=1 30462 MHSWERLAVLVLLGAAACGEEAWACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 151 26.9 3 7 7 4 4 0.871 1.605 1.02 5 5 5 - - - 1.165333333 0.387982388 tr|A6XNE2|A6XNE2_HUMAN 100 1.00E-128 gi|55249559|gb|AAH40146.1| CFD protein [Homo sapiens] 96.54 2.00E-132 sp|P00746|CFAD_HUMAN Complement factor D OS=Homo sapiens GN=CFD PE=1 SV=5 100 4.00E-132 A6XNE2 A6XNE2_HUMAN Complement factor D preproprotein OS=Homo sapiens PE=2 SV=1 mlr3307 105 5.00E-23 COG5640 Secreted trypsin-like serine protease O Posttranslational modification, protein turnover, chaperones ; K01334|1|2e-132|471|hsa:1675|component factor D [EC:3.4.21.46] GO:0030168//platelet activation;GO:0006957//complement activation, alternative pathway;GO:0007219//Notch signaling pathway;GO:0006508//proteolysis;GO:0002576//platelet degranulation GO:0004252//serine-type endopeptidase activity GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen 514 sp|P10909|CLUS_HUMAN Clusterin OS=Homo sapiens GN=CLU PE=1 SV=1 62157 MMKTLLLFVGLLLTWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHMLDVMQDHFSRASSIIDELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLMPFSPYEPLNFHAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVTTVASHTSDSDVPSGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVAEKALQEYRKKHREE 474 32.1 - 42 42 12 12 0.752 2.939 0.808 17 14 10 * - - 1.499666667 1.246813672 sp|P10909|CLUS_HUMAN 100 1.00E-75 gi|26665859|gb|AAN78322.1| CLU [Homo sapiens] 100 0 sp|P10909|CLUS_HUMAN Clusterin OS=Homo sapiens GN=CLU PE=1 SV=1 100 9.00E-33 Q6LDQ3 Q6LDQ3_HUMAN Sulfated glycoprotein 2 (Fragment) OS=Homo sapiens PE=2 SV=1 - - - - - - - - GO:0061077//chaperone-mediated protein folding;GO:0009615//response to virus;GO:0051788//response to misfolded protein;GO:0030168//platelet activation;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0032463//negative regulation of protein homooligomerization;GO:0050821//protein stabilization;GO:0043691//reverse cholesterol transport;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0006629//lipid metabolic process;GO:0006958//complement activation, classical pathway;GO:0002576//platelet degranulation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0001836//release of cytochrome c from mitochondria;GO:0045087//innate immune response;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway GO:0031625//ubiquitin protein ligase binding;GO:0051787//misfolded protein binding;GO:0016887//ATPase activity GO:0034366//spherical high-density lipoprotein particle;GO:0031093//platelet alpha granule lumen;GO:0031966//mitochondrial membrane;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0005783//endoplasmic reticulum;GO:0042583//chromaffin granule;GO:0005634//nucleus;GO:0031012//extracellular matrix 515 sp|P22692|IBP4_HUMAN Insulin-like growth factor-binding protein 4 OS=Homo sapiens GN=IGFBP4 PE=1 SV=2 >tr|A0A024R1U8|A0A024R1U8_HUMAN Insulin-like growth factor binding protein 4, isoform CRA_a OS=Homo sapiens GN=IGFBP4 PE=4 SV=1 33068 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDKDEGDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADSFRE 547 15.9 - 17 17 4 4 1.34 1.539 1.925 15 15 15 * * * 1.601333333 0.29743963 sp|P22692|IBP4_HUMAN 100 2.00E-36 gi|114793741|pdb|2DSP|B Chain B, Structural Basis For The Inhibition Of Insulin-Like Growth Factors By Igf Binding Proteins >gi|114793743|pdb|2DSQ|B Chain B, Structural Basis For The Inhibition Of Insulin-Like Growth Factors By Igf Binding Proteins >gi|114793745|pdb|2DSQ|A Chain A, Structural Basis For The Inhibition Of Insulin-Like Growth Factors By Igf Binding Proteins 100 4.00E-126 sp|P22692|IBP4_HUMAN Insulin-like growth factor-binding protein 4 OS=Homo sapiens GN=IGFBP4 PE=1 SV=2 100 6.00E-125 H2NU76 H2NU76_PONAB Uncharacterized protein OS=Pongo abelii GN=LOC100433229 PE=4 SV=1 - - - - - - - K10138|1|2e-22|106|mcc:696868|insulin-like growth factor-binding protein 3 GO:0044342//type B pancreatic cell proliferation;GO:0006259//DNA metabolic process;GO:0006954//inflammatory response;GO:0043410//positive regulation of MAPK cascade;GO:0001558//regulation of cell growth;GO:0001501//skeletal system development;GO:0010906//regulation of glucose metabolic process;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway GO:0005520//insulin-like growth factor binding GO:0005615//extracellular space 516 sp|Q16610|ECM1_HUMAN Extracellular matrix protein 1 OS=Homo sapiens GN=ECM1 PE=1 SV=2 67099 MGTTARAALVLTYLAVASAASEGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQICLPNRQHVVYGPWNLPQSSYSHLTRQGETLNFLEIGYSRCCHCRSHTNRLECAKLVWEEAMSRFCEAEFSVKTRPHWCCTRQGEARFSCFQEEAPQPHYQLRACPSHQPDISSGLELPFPPGVPTLDNIKNICHLRRFRSVPRNLPATDPLQRELLALIQLEREFQRCCRQGNNHTCTWKAWEDTLDKYCDREYAVKTHHHLCCRHPPSPTRDECFARRAPYPNYDRDILTIDIGRVTPNLMGHLCGNQRVLTKHKHIPGLIHNMTARCCDLPFPEQACCAEEEKLTFINDLCGPRRNIWRDPALCCYLSPGDEQVNCFNINYLRNVALVSGDTENAKGQGEQGSTGGTNISSTSEPKEE 2676 42.2 - 156 156 17 17 1.244 1.188 1.258 91 101 93 - - - 1.23 0.037040518 sp|Q16610|ECM1_HUMAN 100 1.00E-26 gi|119573932|gb|EAW53547.1| extracellular matrix protein 1, isoform CRA_d [Homo sapiens] 100 0 sp|Q16610|ECM1_HUMAN Extracellular matrix protein 1 OS=Homo sapiens GN=ECM1 PE=1 SV=2 100 0 C8CHS3 C8CHS3_HUMAN Truncated extracellular matrix protein 1 OS=Homo sapiens GN=ECM1 PE=4 SV=1 - - - - - - - - GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030502//negative regulation of bone mineralization;GO:0045766//positive regulation of angiogenesis;GO:2000404//regulation of T cell migration;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB cascade;GO:0006954//inflammatory response;GO:0002828//regulation of type 2 immune response;GO:0010466//negative regulation of peptidase activity GO:0004871//signal transducer activity;GO:0043236//laminin binding;GO:0008022//protein C-terminus binding;GO:0002020//protease binding;GO:0005134//interleukin-2 receptor binding GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 517 tr|A0A087WYV8|A0A087WYV8_HUMAN Fibrillin-2 OS=Homo sapiens GN=FBN2 PE=4 SV=1 364362 MGRRRRLCLQLYFLWLGCVVLWAQGTAGQPQPPPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQQDVLRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCITQPCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPEACYECKINGYSKKDSRQKRSIHEPDPTAVEQISLESVDMDSPVNMKFNLSHLGSKEHILELRPAIQPLNNHIRYVISQGNDDSVFRIHQRNGLSYLHTAKKKLMPGTYTLEITSIPLYKKKELKKLEESNEDDYLLGELGEALRMRLQIQLY 427 4 1 23 14 7 6 1.505 1.451 1.602 10 10 9 - * * 1.519333333 0.076513615 tr|A0A087WYV8|A0A087WYV8_HUMAN 100 0 gi|62089050|dbj|BAD92972.1| fibrillin 2 (congenital contractural arachnodactyly) variant [Homo sapiens] 99.86 0 sp|P35556|FBN2_HUMAN Fibrillin-2 OS=Homo sapiens GN=FBN2 PE=1 SV=3 100 0 Q4R3X4 Q4R3X4_MACFA Testis cDNA clone: QtsA-13547, similar to human fibrillin 2 (congenital contractural arachnodactyly)(FBN2), OS=Macaca fascicularis PE=2 SV=1 - - - - - - - K06825|1|0.0|3444|mdo:100025769|fibrillin 1 GO:0045669//positive regulation of osteoblast differentiation;GO:0035583//sequestering of TGFbeta in extracellular matrix;GO:0030501//positive regulation of bone mineralization;GO:0060346//bone trabecula formation GO:0005509//calcium ion binding;GO:0005201//extracellular matrix structural constituent GO:0001527//microfibril 518 sp|P61960|UFM1_HUMAN Ubiquitin-fold modifier 1 OS=Homo sapiens GN=UFM1 PE=1 SV=1 11298 MSKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRIIPRDRVGSC 87 50.6 - 6 6 2 2 0.717 1.081 0.748 3 3 3 - - - 0.848666667 0.201802709 sp|P61960|UFM1_HUMAN 100 2.00E-42 gi|410947316|ref|XP_003980396.1| PREDICTED: uncharacterized protein LOC101089319 [Felis catus] 100 2.00E-43 sp|Q4R4I2|UFM1_MACFA Ubiquitin-fold modifier 1 OS=Macaca fascicularis GN=UFM1 PE=3 SV=1 100 1.00E-29 G1QQ93 G1QQ93_NOMLE Uncharacterized protein (Fragment) OS=Nomascus leucogenys GN=UFM1 PE=4 SV=1 - - - - - - - K12162|1|2e-43|174|ssc:100522509|ubiquitin-fold modifier 1 GO:0071569//protein ufmylation - GO:0005737//cytoplasm;GO:0005634//nucleus 519 sp|P14543|NID1_HUMAN Nidogen-1 OS=Homo sapiens GN=NID1 PE=1 SV=3 148268 MLASSSRIRAAWTRALLLPLLLAGPVGCLSRQELFPFGPGQGDLELEDGDDFVSPALELSGALRFYDRSDIDAVYVTTNGIIATSEPPAKESHPGLFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSITQRAAECVHRGFPEISFQPSSAVVVTWESVAPYQGPSRDPDQKGKRNTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKKENNQVPAVVAFSQGSVGFLWKSNGAYNIFANDRESVENLAKSSNSGQQGVWVFEIGSPATTNGVVPADVILGTEDGAEYDDEDEDYDLATTRLGLEDVGTTPFSYKALRRGGADTYSVPSVLSPRRAATERPLGPPTERTRSFQLAVETFHQQHPQVIDVDEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGSSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPVGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIKQRFSGIDEHGHLTIDTELEGRVPQIPFGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGASPSRIYTYQWRQTITFQECVHDDSRPALPSTQQLSVDSVFVLYNQEEKILRYALSNSIGPVREGSPDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQHEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPCLSTVAPPIHQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLEGNTMRKTEAKAFLHVPAKVIIGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKALEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAFQPHKQTRLYGITTALSQCPQGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIEQK 1115 13.1 - 50 45 13 12 1.657 2.033 2.312 28 28 28 - * * 2.000666667 0.328694894 sp|P14543|NID1_HUMAN 100 0 gi|115298674|ref|NP_002499.2| nidogen-1 precursor [Homo sapiens] >gi|251757450|sp|P14543.3|NID1_HUMAN RecName: Full=Nidogen-1; Short=NID-1; AltName: Full=Entactin; Flags: Precursor 100 0 sp|P14543|NID1_HUMAN Nidogen-1 OS=Homo sapiens GN=NID1 PE=1 SV=3 99.12 0 H2Q1E0 H2Q1E0_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000116962 PE=4 SV=1 - - - - - - - K06826|1|0.0|2475|hsa:4811|nidogen (entactin) GO:0007160//cell-matrix adhesion;GO:0010811//positive regulation of cell-substrate adhesion;GO:0032836//glomerular basement membrane development GO:0043237//laminin-1 binding;GO:0005518//collagen binding;GO:0005509//calcium ion binding GO:0005605//basal lamina;GO:0071944//cell periphery 520 tr|Q6FGL0|Q6FGL0_HUMAN Galectin (Fragment) OS=Homo sapiens GN=LGALS3 PE=2 SV=1 28940 MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSAPGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYNMI 299 23.2 3 22 22 5 5 1.253 1.213 1.254 12 13 13 * - * 1.24 0.023388031 tr|Q6FGL0|Q6FGL0_HUMAN 100 5.00E-09 gi|119601065|gb|EAW80659.1| hCG22119, isoform CRA_b [Homo sapiens] 100 7.00E-10 sp|P17931|LEG3_HUMAN Galectin-3 OS=Homo sapiens GN=LGALS3 PE=1 SV=5 100 7.00E-75 G3QLN6 G3QLN6_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=LGALS3 PE=4 SV=1 - - - - - - - K06831|1|7e-76|283|pon:100453870|galectin-3 GO:0008380//RNA splicing;GO:0045087//innate immune response;GO:0001501//skeletal system development;GO:0030154//cell differentiation;GO:0006397//mRNA processing;GO:0030198//extracellular matrix organization GO:0019863//IgE binding;GO:0030246//carbohydrate binding GO:0005681//spliceosomal complex;GO:0005743//mitochondrial inner membrane;GO:0005578//proteinaceous extracellular matrix;GO:0005886//plasma membrane 521 sp|P21281|VATB2_HUMAN V-type proton ATPase subunit B, brain isoform OS=Homo sapiens GN=ATP6V1B2 PE=1 SV=3 63500 MALRAMRGIVNGAAPELPVPTGGPAVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTVFETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH 257 11.9 - 10 10 4 4 0.575 0.708 0.595 9 9 8 * * * 0.626 0.071714713 sp|P21281|VATB2_HUMAN 100 0 gi|19913428|ref|NP_001684.2| V-type proton ATPase subunit B, brain isoform [Homo sapiens] >gi|12643271|sp|P21281.3|VATB2_HUMAN RecName: Full=V-type proton ATPase subunit B, brain isoform; Short=V-ATPase subunit B 2; AltName: Full=Endomembrane proton pump 58 kDa subunit; AltName: Full=HO57; AltName: Full=Vacuolar proton pump subunit B 2 >gi|13111865|gb|AAH03100.1| ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 [Homo sapiens] >gi|119584162|gb|EAW63758.1| ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2, isoform CRA_a [Homo sapiens] >gi|119584163|gb|EAW63759.1| ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2, isoform CRA_a [Homo sapiens] 100 0 sp|P21281|VATB2_HUMAN V-type proton ATPase subunit B, brain isoform OS=Homo sapiens GN=ATP6V1B2 PE=1 SV=3 100 0 G1QJ94 G1QJ94_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=ATP6V1B2 PE=3 SV=1 YBR127c 795 0 COG1156 Archaeal/vacuolar-type H+-ATPase subunit B C Energy production and conversion ; K02147|1|0.0|1055|ptr:464033|V-type H+-transporting ATPase subunit B [EC:3.6.3.14] GO:0033572//transferrin transport;GO:0090382//phagosome maturation;GO:0008286//insulin receptor signaling pathway;GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0007035//vacuolar acidification;GO:0051701//interaction with host;GO:0042777//plasma membrane ATP synthesis coupled proton transport GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0005524//ATP binding GO:0005773//vacuole;GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0005902//microvillus;GO:0042470//melanosome;GO:0016021//integral to membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0005886//plasma membrane 522 tr|Q5U0A0|Q5U0A0_HUMAN Proteasome subunit alpha type OS=Homo sapiens PE=2 SV=1 30838 MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLASTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVIKDI 300 19.9 1 12 12 4 4 0.937 0.723 0.936 8 8 8 - * - 0.865333333 0.123265297 tr|Q5U0A0|Q5U0A0_HUMAN 100 5.00E-49 gi|67970043|dbj|BAE01367.1| unnamed protein product [Macaca fascicularis] 99.59 5.00E-140 sp|P28066|PSA5_HUMAN Proteasome subunit alpha type-5 OS=Homo sapiens GN=PSMA5 PE=1 SV=3 100 2.00E-103 B4E2V4 B4E2V4_HUMAN Proteasome (Prosome, macropain) subunit, alpha type, 5, isoform CRA_c OS=Homo sapiens GN=PSMA5 PE=2 SV=1 SPAC323.02c 311 4.00E-85 COG0638 20S proteasome, alpha and beta subunits O Posttranslational modification, protein turnover, chaperones ; K02729|1|6e-140|496|cfa:100856348|20S proteasome subunit alpha 5 [EC:3.4.25.1] GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0016032//viral reproduction;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0005515//protein binding;GO:0004298//threonine-type endopeptidase activity GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0019773//proteasome core complex, alpha-subunit complex 523 sp|Q5JXB2|UE2NL_HUMAN Putative ubiquitin-conjugating enzyme E2 N-like OS=Homo sapiens GN=UBE2NL PE=1 SV=1 20712 MAELPHRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGESKDSPFEGGTFKRELLLAEEYPMAAPKVRFMTKIYHPNVDKLERISLDILKDKWSPALQIRTVLLSIQALLNAPNPDDPLANDVVEQWKTNEAQAIETARAWTRLYAMNSI 62 11.8 1 4 4 2 2 1.197 1.04 0.873 2 2 2 - - - 1.036666667 0.162025718 sp|Q5JXB2|UE2NL_HUMAN 100 1.00E-84 gi|6941766|emb|CAB72341.1| ubiquitin-conjugating enzyme E2N-like [Homo sapiens] >gi|317040122|gb|ADU87626.1| epididymis tissue protein Li 174 [Homo sapiens] 100 2.00E-85 sp|Q5JXB2|UE2NL_HUMAN Putative ubiquitin-conjugating enzyme E2 N-like OS=Homo sapiens GN=UBE2NL PE=5 SV=1 100 5.00E-84 E9KL27 E9KL27_HUMAN Epididymis tissue protein Li 174 OS=Homo sapiens PE=2 SV=1 YDR092w 203 1.00E-52 COG5078 Ubiquitin-protein ligase O Posttranslational modification, protein turnover, chaperones ; K10580|1|2e-85|313|hsa:389898|ubiquitin-conjugating enzyme E2 N [EC:6.3.2.19] GO:0070534//protein K63-linked ubiquitination;GO:0033182//regulation of histone ubiquitination;GO:0008063//Toll signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0000724//double-strand break repair via homologous recombination;GO:0034134//toll-like receptor 2 signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB cascade;GO:0050852//T cell receptor signaling pathway;GO:0031058//positive regulation of histone modification;GO:0051443//positive regulation of ubiquitin-protein ligase activity;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0000729//DNA double-strand break processing;GO:0006301//postreplication repair;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034130//toll-like receptor 1 signaling pathway;GO:0045739//positive regulation of DNA repair GO:0043130//ubiquitin binding;GO:0004842//ubiquitin-protein ligase activity;GO:0005524//ATP binding GO:0035370//UBC13-UEV1A complex;GO:0005829//cytosol;GO:0000151//ubiquitin ligase complex;GO:0031372//UBC13-MMS2 complex;GO:0005634//nucleus 524 sp|P16870|CBPE_HUMAN Carboxypeptidase E OS=Homo sapiens GN=CPE PE=1 SV=1 60513 MAGRGGSALLALCGALAACGWLLGAEAQEPGAPAAGMRRRRRLQQEDGISFEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNMKKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGSAHEYSSSPDDAIFQSLARAYSSFNPAMSDPNRPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATISVEGIDHDVTSAKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVPYSPAAGVDFELESFSERKEEEKEELMEWWKMMSETLNF 563 27.7 - 32 32 10 10 1.214 1.358 1.7 17 17 17 * * * 1.424 0.249631729 sp|P16870|CBPE_HUMAN 100 0 gi|4503009|ref|NP_001864.1| carboxypeptidase E preproprotein [Homo sapiens] >gi|115892|sp|P16870.1|CBPE_HUMAN RecName: Full=Carboxypeptidase E; Short=CPE; AltName: Full=Carboxypeptidase H; Short=CPH; AltName: Full=Enkephalin convertase; AltName: Full=Prohormone-processing carboxypeptidase; Flags: Precursor >gi|21707499|gb|AAH33866.1| Carboxypeptidase E [Homo sapiens] >gi|31565487|gb|AAH53612.1| Carboxypeptidase E [Homo sapiens] >gi|119625222|gb|EAX04817.1| carboxypeptidase E, isoform CRA_a [Homo sapiens] >gi|119625223|gb|EAX04818.1| carboxypeptidase E, isoform CRA_a [Homo sapiens] 100 0 sp|P16870|CBPE_HUMAN Carboxypeptidase E OS=Homo sapiens GN=CPE PE=1 SV=1 100 0 H2PEP4 H2PEP4_PONAB Uncharacterized protein OS=Pongo abelii GN=CPE PE=4 SV=1 BH3831 58.9 2.00E-08 COG2866 Predicted carboxypeptidase E Amino acid transport and metabolism ; K01294|1|0.0|844|hsa:1363|carboxypeptidase E [EC:3.4.17.10] GO:0034230//enkephalin processing;GO:0043171//peptide catabolic process;GO:0007218//neuropeptide signaling pathway;GO:0072657//protein localization to membrane;GO:0009790//embryo development;GO:0006464//cellular protein modification process;GO:2000173//negative regulation of branching morphogenesis of a nerve;GO:0030070//insulin processing;GO:0006508//proteolysis;GO:0003214//cardiac left ventricle morphogenesis GO:0050839//cell adhesion molecule binding;GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity;GO:0050897//cobalt ion binding;GO:0019904//protein domain specific binding;GO:0042043//neurexin family protein binding GO:0045121//membrane raft;GO:0030658//transport vesicle membrane;GO:0031045//dense core granule;GO:0097060//synaptic membrane;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0030425//dendrite;GO:0030667//secretory granule membrane;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0043204//perikaryon 525 tr|B3KUR8|B3KUR8_HUMAN cDNA FLJ40483 fis, clone TESTI2043758, highly similar to Neurofascin OS=Homo sapiens PE=2 SV=1 76803 MDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRHQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVHLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGNCPCSPWH 165 11 4 9 9 5 5 0.704 0.637 0.595 5 5 4 - * - 0.645333333 0.054975752 tr|B3KUR8|B3KUR8_HUMAN 100 0 gi|310942942|pdb|3P3Y|A Chain A, Crystal Structure Of Neurofascin Homophilic Adhesion Complex In Space Group P6522 >gi|310942943|pdb|3P40|A Chain A, Crystal Structure Of Neurofascin Adhesion Complex In Space Group P3221 99.32 0 sp|O94856|NFASC_HUMAN Neurofascin OS=Homo sapiens GN=NFASC PE=1 SV=4 100 0 B3KUR8 B3KUR8_HUMAN cDNA FLJ40483 fis, clone TESTI2043758, highly similar to Neurofascin OS=Homo sapiens PE=2 SV=1 - - - - - - - K06757|1|0.0|1217|hsa:23114|neurofascin - - 526 sp|P07737|PROF1_HUMAN Profilin-1 OS=Homo sapiens GN=PFN1 PE=1 SV=2 18562 MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFYVNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY 1255 35.7 - 64 64 4 4 0.796 0.652 0.703 41 42 42 - * - 0.717 0.073013697 sp|P07737|PROF1_HUMAN 100 8.00E-69 gi|157831080|pdb|1FIK|A Chain A, Human Platelet Profilin I Crystallized In Low Salt >gi|157831081|pdb|1FIL|A Chain A, Human Platelet Profilin I Crystallized In High Salt Actin- Binding Protein >gi|159795064|pdb|2PAV|P Chain P, Ternary Complex Of Profilin-actin With The Last Poly-pro Of Human Vasp >gi|160285766|pdb|2PBD|P Chain P, Ternary Complex Of Profilin-actin With The Poly-pro-gab Domain Of Vasp* >gi|197107235|pdb|3CHW|P Chain P, Complex Of Dictyostelium Discoideum Actin With Profilin And The Last Poly-Pro Of Human Vasp 100 2.00E-70 sp|P07737|PROF1_HUMAN Profilin-1 OS=Homo sapiens GN=PFN1 PE=1 SV=2 100 6.00E-69 Q53Y44 Q53Y44_HUMAN Profilin OS=Homo sapiens GN=PFN1 PE=2 SV=1 - - - - - - - K05759|1|1e-70|264|mcc:710753|profilin GO:0071363//cellular response to growth factor stimulus;GO:0030168//platelet activation;GO:0042989//sequestering of actin monomers;GO:0051054//positive regulation of DNA metabolic process;GO:0001843//neural tube closure;GO:0002576//platelet degranulation;GO:0050434//positive regulation of viral transcription;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051496//positive regulation of stress fiber assembly GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005102//receptor binding;GO:0003779//actin binding;GO:0070064//proline-rich region binding;GO:0017048//Rho GTPase binding GO:0043005//neuron projection;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0045202//synapse 527 sp|Q14315|FLNC_HUMAN Filamin-C OS=Homo sapiens GN=FLNC PE=1 SV=3 341775 MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKAKLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPAVFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP 1614 14.2 - 88 55 32 26 0.509 0.541 0.413 34 37 35 - * * 0.487666667 0.066613312 sp|Q14315|FLNC_HUMAN 100 0 gi|116805322|ref|NP_001449.3| filamin-C isoform a [Homo sapiens] >gi|254763419|sp|Q14315.3|FLNC_HUMAN RecName: Full=Filamin-C; Short=FLN-C; Short=FLNc; AltName: Full=ABP-280-like protein; AltName: Full=ABP-L; AltName: Full=Actin-binding-like protein; AltName: Full=Filamin-2; AltName: Full=Gamma-filamin >gi|7677526|gb|AAF67190.1|AF252549_1 gamma-filamin [Homo sapiens] >gi|119604097|gb|EAW83691.1| filamin C, gamma (actin binding protein 280), isoform CRA_c [Homo sapiens] >gi|190192200|dbj|BAG48314.1| filamin C [Homo sapiens] 100 0 sp|Q14315|FLNC_HUMAN Filamin-C OS=Homo sapiens GN=FLNC PE=1 SV=3 100 0 Q59H94 Q59H94_HUMAN Gamma filamin variant (Fragment) OS=Homo sapiens PE=1 SV=1 ECU09g0290 143 5.00E-33 COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) Z Cytoskeleton ; K04437|1|0.0|5312|ssc:100518997|filamin GO:0034329//cell junction assembly GO:0003779//actin binding;GO:0030506//ankyrin binding GO:0030018//Z disc;GO:0005856//cytoskeleton;GO:0043034//costamere;GO:0042383//sarcolemma;GO:0005829//cytosol 528 tr|Q53GD8|Q53GD8_HUMAN Peptidyl-prolyl cis-trans isomerase (Fragment) OS=Homo sapiens PE=2 SV=1 36197 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLFETKRFKGTESISKVSKQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGERARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 71 9.8 1 6 6 2 2 0.692 0.587 0.656 4 4 4 - * - 0.645 0.053357286 tr|Q53GD8|Q53GD8_HUMAN 100 5.00E-36 gi|241913087|pdb|2KFV|A Chain A, Structure Of The Amino-Terminal Domain Of Human Fk506- Binding Protein 3 NORTHEAST STRUCTURAL GENOMICS Consortium Target Ht99a 99.11 2.00E-127 sp|Q00688|FKBP3_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens GN=FKBP3 PE=1 SV=1 100 6.00E-127 Q53GD8 Q53GD8_HUMAN Peptidyl-prolyl cis-trans isomerase (Fragment) OS=Homo sapiens PE=2 SV=1 SPBC839.17c 97.8 1.00E-20 COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 O Posttranslational modification, protein turnover, chaperones ; K09570|1|2e-127|454|ptr:452883|FK506-binding protein 3 [EC:5.2.1.8] GO:0006457//protein folding;GO:0000413//protein peptidyl-prolyl isomerization GO:0004872//receptor activity;GO:0005528//FK506 binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity GO:0016020//membrane;GO:0005634//nucleus 529 tr|C0LQF2|C0LQF2_HUMAN Deoxyribonuclease II (Fragment) OS=Homo sapiens PE=2 SV=1 43784 LTCYGDSGQPVDWFVVYKLPALRGSGEAAQRGLQYKYLDESSGGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPPQPSKAQDSSMRGHTKGVLLLDHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYRQTLLCVSFPFAQFSKMGKQLTYTYPWVYNYQLEGIFAQEFPDLEYVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYSGWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNVNQIAFPGPAGPSFNSTEDHSKWCVSPKGPWTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPCNGMARKPSRAYKI 213 14.8 - 11 11 4 4 1.044 0.808 1.25 6 6 6 - - - 1.034 0.221169618 tr|C0LQF2|C0LQF2_HUMAN 100 0 gi|224809789|gb|ACN63522.1| deoxyribonuclease II [Homo sapiens] 99.42 0 sp|O00115|DNS2A_HUMAN Deoxyribonuclease-2-alpha OS=Homo sapiens GN=DNASE2 PE=1 SV=2 100 0 C0LQF2 C0LQF2_HUMAN Deoxyribonuclease II (Fragment) OS=Homo sapiens PE=2 SV=1 - - - - - - - K01158|1|0.0|672|hsa:1777|deoxyribonuclease II [EC:3.1.22.1] GO:0006915//apoptotic process;GO:0006308//DNA catabolic process;GO:0030218//erythrocyte differentiation GO:0003677//DNA binding;GO:0004531//deoxyribonuclease II activity GO:0005764//lysosome 530 tr|U3KQA9|U3KQA9_HUMAN Uncharacterized protein (Fragment) OS=Homo sapiens PE=3 SV=3 33211 XEFTHLEFPRRVLPKELGQRMLYRDQNMTGWAYKKIELEDLRFPLVCGEGKKARVMATIGVTRGLGDHSLKVCSSTLPIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATVDRVLSAYEPNDHSSPTMAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCP 55 4.4 15 2 2 1 1 0.697 0.668 0.578 2 2 2 - - * 0.647666667 0.062051054 tr|U3KQA9|U3KQA9_HUMAN 100 2.00E-58 gi|28395033|ref|NP_786886.1| rho-related GTP-binding protein RhoC precursor [Homo sapiens] >gi|111494248|ref|NP_001036143.1| rho-related GTP-binding protein RhoC precursor [Homo sapiens] >gi|111494251|ref|NP_001036144.1| rho-related GTP-binding protein RhoC precursor [Homo sapiens] >gi|114051153|ref|NP_001039603.1| rho-related GTP-binding protein RhoC precursor [Bos taurus] >gi|157824176|ref|NP_001099931.1| rho-related GTP-binding protein RhoC [Rattus norvegicus] >gi|160415213|ref|NP_031510.2| rho-related GTP-binding protein RhoC precursor [Mus musculus] >gi|197103054|ref|NP_001125261.1| rho-related GTP-binding protein RhoC precursor [Pongo abelii] >gi|132543|sp|P08134.1|RHOC_HUMAN RecName: Full=Rho-related GTP-binding protein RhoC; AltName: Full=Rho cDNA clone 9; Short=h9; Flags: Precursor >gi|46397862|sp|Q62159.2|RHOC_MOUSE RecName: Full=Rho-related GTP-binding protein RhoC; AltName: Full=Silica-induced gene 61 protein; Short=SIG-61; Flags: Precursor >gi|75055126|sp|Q5RCK9.1|RHOC_PONAB RecName: Full=Rho-related GTP-binding protein RhoC; Flags: Precursor >gi|119361642|sp|Q1RMJ6.1|RHOC_BOVIN RecName: Full=Rho-related GTP-binding protein RhoC; Flags: Precursor >gi|20379118|gb|AAM21119.1|AF498972_1 small GTP binding protein RhoC [Homo sapiens] >gi|407699|gb|AAC33179.1| GTPase [Homo sapiens] >gi|13435508|gb|AAH04627.1| Ras homolog gene family, member C [Mus musculus] >gi|13938243|gb|AAH07245.1| Ras homolog gene family, member C [Homo sapiens] >gi|14327919|gb|AAH09177.1| Ras homolog gene family, member C [Homo sapiens] >gi|31217371|gb|AAH52808.1| Ras homolog gene family, member C [Homo sapiens] >gi|47496667|emb|CAG29356.1| ARHC [Homo sapiens] >gi|92097568|gb|AAI14860.1| Ras homolog gene family, member C [Bos taurus] >gi|119576938|gb|EAW56534.1| hCG2043376, isoform CRA_b [Homo sapiens] >gi|119576939|gb|EAW56535.1| hCG2043376, isoform CRA_b [Homo sapiens] >gi|119576940|gb|EAW56536.1| hCG2043376, isoform CRA_b [Homo sapiens] >gi|119576943|gb|EAW56539.1| hCG2043376, isoform CRA_b [Homo sapiens] >gi|148675614|gb|EDL07561.1| ras homolog gene family, member C, isoform CRA_a [Mus musculus] >gi|148675615|gb|EDL07562.1| ras homolog gene family, member C, isoform CRA_a [Mus musculus] >gi|148675616|gb|EDL07563.1| ras homolog gene family, member C, isoform CRA_a [Mus musculus] >gi|148675617|gb|EDL07564.1| ras homolog gene family, member C, isoform CRA_a [Mus musculus] >gi|148675618|gb|EDL07565.1| ras homolog gene family, member C, isoform CRA_a [Mus musculus] >gi|296489349|tpg|DAA31462.1| TPA: rho-related GTP-binding protein RhoC precursor [Bos taurus] >gi|344249320|gb|EGW05424.1| Rho-related GTP-binding protein RhoC [Cricetulus griseus] >gi|351708053|gb|EHB10972.1| Rho-related GTP-binding protein RhoC [Heterocephalus glaber] >gi|432103975|gb|ELK30808.1| Rho-related GTP-binding protein RhoC [Myotis davidii] >gi|444724674|gb|ELW65273.1| Rho-related GTP-binding protein RhoC [Tupaia chinensis] 100 4.00E-59 sp|Q9PSX7|RHOC_CHICK Rho-related GTP-binding protein RhoC OS=Gallus gallus GN=RHOC PE=1 SV=1 100 5.00E-58 Q5JR08 Q5JR08_HUMAN Ras homolog gene family, member C (Fragment) OS=Homo sapiens GN=RHOC PE=2 SV=1 SPAC16A10.04 171 1.00E-42 COG1100 GTPase SAR1 and related small G proteins R General function prediction only ; K07857|1|6e-102|370|tgu:100221682|Ras homolog gene family, member C!K04513|2|2e-59|229|nve:NEMVE_v1g243859|Ras homolog gene family, member A GO:0006470//protein dephosphorylation GO:0004722//protein serine/threonine phosphatase activity - 531 tr|B9A041|B9A041_HUMAN Malate dehydrogenase, cytoplasmic OS=Homo sapiens GN=MDH1 PE=1 SV=1 29279 MVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA 238 19 1 11 11 4 4 0.905 0.753 0.838 8 8 8 - * - 0.832 0.076177424 tr|B9A041|B9A041_HUMAN 100 5.00E-121 gi|397521717|ref|XP_003830935.1| PREDICTED: malate dehydrogenase, cytoplasmic isoform 1 [Pan paniscus] 100 6.00E-122 sp|P40925|MDHC_HUMAN Malate dehydrogenase, cytoplasmic OS=Homo sapiens GN=MDH1 PE=1 SV=4 100 2.00E-120 B9A041 B9A041_HUMAN Malate dehydrogenase, cytoplasmic OS=Homo sapiens GN=MDH1 PE=4 SV=1 Rv1240 201 8.00E-52 COG0039 Malate/lactate dehydrogenases C Energy production and conversion ; K00025|1|1e-121|435|ptr:459271|malate dehydrogenase [EC:1.1.1.37] GO:0006107//oxaloacetate metabolic process;GO:0006734//NADH metabolic process;GO:0006108//malate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0044262//cellular carbohydrate metabolic process;GO:0006094//gluconeogenesis GO:0051287//NAD binding;GO:0030060//L-malate dehydrogenase activity;GO:0004470//malic enzyme activity;GO:0047860//diiodophenylpyruvate reductase activity GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005813//centrosome 532 tr|B4DPW5|B4DPW5_HUMAN cDNA FLJ59374, highly similar to Homo sapiens caldesmon 1 (CALD1), transcript variant 2, mRNA OS=Homo sapiens PE=2 SV=1 77818 MDDFERRRELRRQKREVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEGKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEKQSVDKVTSPTKEPVSKETHAVK 781 16.5 4 47 47 9 9 0.445 0.426 0.324 31 31 30 * - * 0.398333333 0.065071755 tr|B4DPW5|B4DPW5_HUMAN 100 4.00E-97 gi|221043146|dbj|BAH13250.1| unnamed protein product [Homo sapiens] 100 3.00E-26 sp|Q05682|CALD1_HUMAN Caldesmon OS=Homo sapiens GN=CALD1 PE=1 SV=3 100 1.00E-96 B7Z6G4 B7Z6G4_HUMAN cDNA FLJ53193, highly similar to Homo sapiens caldesmon 1 (CALD1), transcript variant 5, mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K12327|1|3e-98|359|ptr:472523|caldesmon GO:0051017//actin filament bundle assembly;GO:0032092//positive regulation of protein binding;GO:0006928//cellular component movement;GO:0006936//muscle contraction GO:0005516//calmodulin binding;GO:0003779//actin binding;GO:0017022//myosin binding;GO:0005523//tropomyosin binding GO:0005829//cytosol;GO:0030016//myofibril;GO:0043025//neuronal cell body;GO:0005884//actin filament;GO:0014069//postsynaptic density;GO:0030478//actin cap;GO:0005886//plasma membrane 533 sp|P25398|RS12_HUMAN 40S ribosomal protein S12 OS=Homo sapiens GN=RPS12 PE=1 SV=3 20076 MAEEGIAAGGVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK 165 24.2 - 10 10 3 3 0.841 0.65 0.647 5 5 5 - * - 0.712666667 0.111150049 sp|P25398|RS12_HUMAN 100 4.00E-66 gi|73696562|gb|AAZ81002.1| ribosomal protein S12 [Macaca mulatta] 100 5.00E-71 sp|P25398|RS12_HUMAN 40S ribosomal protein S12 OS=Homo sapiens GN=RPS12 PE=1 SV=3 100 2.00E-69 G1NUW4 G1NUW4_MYOLU 40S ribosomal protein S12 OS=Myotis lucifugus PE=3 SV=1 SPCC962.04 157 5.00E-39 COG1358 Ribosomal protein HS6-type (S12/L30/L7a) J Translation, ribosomal structure and biogenesis ; K02951|1|2e-72|270|oaa:100075031|small subunit ribosomal protein S12e GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006414//translational elongation;GO:0006415//translational termination;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003735//structural constituent of ribosome GO:0005739//mitochondrion;GO:0022627//cytosolic small ribosomal subunit 534 tr|Q5HYM1|Q5HYM1_HUMAN Putative uncharacterized protein DKFZp686O1553 (Fragment) OS=Homo sapiens GN=DKFZp686O1553 PE=1 SV=1 62159 MSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPGGRLGHLQSQCDS 233 16.9 - 11 10 6 5 2.248 4.01 3.135 8 8 8 * * * 3.131 0.88100681 tr|Q5HYM1|Q5HYM1_HUMAN 100 6.00E-107 gi|193506834|pdb|3DEM|A Chain A, Cub1-egf-cub2 Domain Of Human Masp-1/3 >gi|193506835|pdb|3DEM|B Chain B, Cub1-egf-cub2 Domain Of Human Masp-1/3 79.15 0 sp|P48740|MASP1_HUMAN Mannan-binding lectin serine protease 1 OS=Homo sapiens GN=MASP1 PE=1 SV=3 100 0 Q5HYM1 Q5HYM1_HUMAN Putative uncharacterized protein DKFZp686O1553 (Fragment) OS=Homo sapiens GN=DKFZp686O1553 PE=1 SV=1 mlr3307 60.8 6.00E-09 COG5640 Secreted trypsin-like serine protease O Posttranslational modification, protein turnover, chaperones ; K03992|1|0.0|967|mcc:708206|mannan-binding lectin serine protease 1 [EC:3.4.21.-] GO:0006508//proteolysis;GO:0045916//negative regulation of complement activation;GO:0001867//complement activation, lectin pathway GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0004252//serine-type endopeptidase activity;GO:0042803//protein homodimerization activity GO:0005615//extracellular space 535 tr|A0A087WU42|A0A087WU42_HUMAN Immunoglobulin lambda-like polypeptide 5 OS=Homo sapiens GN=IGLL5 PE=4 SV=1 29536 MAWALLLLTLTQGTGSWAQSALIQPPSVSGSPGQSVTISCTGTSSDVGSYDYVSWYQQHPGTVPKPMIYNVNTQPSGVPDRFSGSKSGNTASMTISGLQAEDEADYTCCKYIYSLCYVFGTGTKVTVLGQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS 187 17.9 16 14 5 3 1 0.814 3.593 0.798 4 3 3 - * - 1.735 1.609095087 tr|A0A087WU42|A0A087WU42_HUMAN 91.06 7.00E-106 gi|21619848|gb|AAH33102.1| IGL@ protein [Homo sapiens] 100 8.00E-56 sp|P0CG04|LAC1_HUMAN Ig lambda-1 chain C regions OS=Homo sapiens GN=IGLC1 PE=1 SV=1 100 9.00E-54 A0M8Q9 A0M8Q9_HUMAN C1 segment protein (Fragment) OS=Homo sapiens GN=C1 segment PE=4 SV=1 - - - - - - - K06554|1|6e-79|293|mcc:100430606|immunoglobulin lambda-like polypeptide 1!K06553|4|8e-59|226|mcc:698694|pre-B lymphocyte gene GO:0045087//innate immune response;GO:0006958//complement activation, classical pathway GO:0003823//antigen binding GO:0005886//plasma membrane;GO:0005576//extracellular region 536 tr|B2R6M6|B2R6M6_HUMAN cDNA, FLJ93024, highly similar to Homo sapiens EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1), transcript variant 1, mRNA OS=Homo sapiens PE=2 SV=1 60522 MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTVYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF 2566 36.7 1 137 137 14 14 1.279 1.314 1.226 87 91 84 * - - 1.273 0.044305756 tr|B2R6M6|B2R6M6_HUMAN 100 1.00E-88 gi|62420274|gb|AAX81993.1| unknown [Homo sapiens] 99.8 0 sp|Q12805|FBLN3_HUMAN EGF-containing fibulin-like extracellular matrix protein 1 OS=Homo sapiens GN=EFEMP1 PE=1 SV=2 100 6.00E-60 C9JPZ9 C9JPZ9_HUMAN EGF-containing fibulin-like extracellular matrix protein 1 (Fragment) OS=Homo sapiens GN=EFEMP1 PE=4 SV=1 - - - - - - - K08023|1|1e-34|148|acs:100560501|latent transforming growth factor beta binding protein GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006355//regulation of transcription, DNA-dependent;GO:0007601//visual perception;GO:0032331//negative regulation of chondrocyte differentiation;GO:0007173//epidermal growth factor receptor signaling pathway GO:0005509//calcium ion binding;GO:0005006//epidermal growth factor-activated receptor activity;GO:0008083//growth factor activity;GO:0005154//epidermal growth factor receptor binding GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 537 sp|P15374|UCHL3_HUMAN Ubiquitin carboxyl-terminal hydrolase isozyme L3 OS=Homo sapiens GN=UCHL3 PE=1 SV=1 30596 MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA 79 13 - 4 4 2 2 1.211 0.565 0.414 2 2 2 - - - 0.73 0.423345013 sp|P15374|UCHL3_HUMAN 100 1.00E-49 gi|281344870|gb|EFB20454.1| hypothetical protein PANDA_016612 [Ailuropoda melanoleuca] 100 2.00E-135 sp|P15374|UCHL3_HUMAN Ubiquitin carboxyl-terminal hydrolase isozyme L3 OS=Homo sapiens GN=UCHL3 PE=1 SV=1 100 2.00E-35 D2HW05 D2HW05_AILME Putative uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca GN=PANDA_016612 PE=4 SV=1 - - - - - - - K05609|1|2e-135|481|aml:100479695|ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12] GO:0006511//ubiquitin-dependent protein catabolic process;GO:0032869//cellular response to insulin stimulus;GO:0045600//positive regulation of fat cell differentiation;GO:0042755//eating behavior;GO:0016579//protein deubiquitination;GO:0060041//retina development in camera-type eye;GO:0007628//adult walking behavior GO:0004221//ubiquitin thiolesterase activity;GO:0008234//cysteine-type peptidase activity;GO:0043130//ubiquitin binding GO:0005739//mitochondrion;GO:0005634//nucleus 538 tr|B2R825|B2R825_HUMAN Alpha-1,4 glucan phosphorylase OS=Homo sapiens PE=2 SV=1 117483 MAKPLTDQEKRRQISIRGIVGVENVAELKKSFNRHLHFTLVKDRNVATTRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDIEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQVEEADDWLRYGNPWEKSRPEFMLPVHFYGKVEHTNTGTKWIDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKASKFGSTRGAGTVFDAFPDQVAIQMNDTHPALAIPELMRIFVDIGKLPWSKAWELTQKTFAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKHLDRIVALFPKDVDRLRRMSLIEEEGSKRINMAHLCIVGSHAVNGVAKIHSDIVKTKVFKDFSELEPDKFQNKTNGITPRRWLLLCNPGLAELIAEKIGEDYVKDLSQLTKLHSFLGDDVFLRELAKVKQENKLKFSQFLETEYKVKINPSSMFDVQVKRIHEYKRQLLNCLHVITMYNRIKKDPKKLFVPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRIDDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPKQPDLFKDIISMLFYHDRFKVFADYEAYVKCQDKVSQLYMNPKAWNTMVLKNIAASGKFSSDRTIKEYAQNIWNVEPSDLKISLSNESNKVNGN 207 13.9 1 16 13 11 9 1.421 0.986 1.152 6 6 6 - - - 1.186333333 0.219522968 tr|B2R825|B2R825_HUMAN 100 0 gi|189053770|dbj|BAG36022.1| unnamed protein product [Homo sapiens] 99.65 0 sp|P06737|PYGL_HUMAN Glycogen phosphorylase, liver form OS=Homo sapiens GN=PYGL PE=1 SV=4 100 0 B2R825 B2R825_HUMAN Phosphorylase OS=Homo sapiens PE=2 SV=1 slr1367 859 0 COG0058 Glucan phosphorylase G Carbohydrate transport and metabolism ; K00688|1|0.0|1695|ptr:742309|starch phosphorylase [EC:2.4.1.1] GO:0005980//glycogen catabolic process;GO:0042593//glucose homeostasis;GO:0006015//5-phosphoribose 1-diphosphate biosynthetic process;GO:0006006//glucose metabolic process;GO:0044281//small molecule metabolic process GO:0008184//glycogen phosphorylase activity;GO:0008144//drug binding;GO:0002060//purine nucleobase binding;GO:0032052//bile acid binding;GO:0005536//glucose binding;GO:0005524//ATP binding;GO:0042803//protein homodimerization activity;GO:0016208//AMP binding;GO:0030170//pyridoxal phosphate binding GO:0005829//cytosol;GO:0005886//plasma membrane 539 tr|V9HW35|V9HW35_HUMAN Epididymis secretory protein Li 55 OS=Homo sapiens GN=HEL-S-55 PE=2 SV=1 21450 MAPIKVGDAIPAVEVFEGEPGNKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGFVEQAEALKAKGVQVVACLSVNDAFVTGEWGRAHKAEGKVRLLADPTGAFGKETDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKALNVEPDGTGLTCSLAPNIISQL 439 41.4 1 25 25 5 5 0.929 0.69 0.922 13 14 13 - * - 0.847 0.136011029 tr|V9HW35|V9HW35_HUMAN 100 8.00E-89 gi|297688287|ref|XP_002821617.1| PREDICTED: peroxiredoxin-5, mitochondrial isoform 2 [Pongo abelii] >gi|395742540|ref|XP_003777768.1| PREDICTED: peroxiredoxin-5, mitochondrial [Pongo abelii] >gi|395742542|ref|XP_003777769.1| PREDICTED: peroxiredoxin-5, mitochondrial [Pongo abelii] 100 6.00E-90 sp|P30044|PRDX5_HUMAN Peroxiredoxin-5, mitochondrial OS=Homo sapiens GN=PRDX5 PE=1 SV=4 100 3.00E-88 H2NCZ8 H2NCZ8_PONAB Uncharacterized protein OS=Pongo abelii GN=LOC100451000 PE=4 SV=1 BMEI1456 124 9.00E-29 COG0678 Peroxiredoxin O Posttranslational modification, protein turnover, chaperones ; K11187|1|9e-90|328|hsa:25824|peroxiredoxin 5, atypical 2-Cys peroxiredoxin [EC:1.11.1.15] GO:0042744//hydrogen peroxide catabolic process;GO:0070995//NADPH oxidation;GO:0043066//negative regulation of apoptotic process;GO:0016480//negative regulation of transcription from RNA polymerase III promoter;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006954//inflammatory response;GO:0060785//regulation of apoptosis involved in tissue homeostasis;GO:0032967//positive regulation of collagen biosynthetic process GO:0005102//receptor binding;GO:0051920//peroxiredoxin activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046983//protein dimerization activity;GO:0004601//peroxidase activity;GO:0001016//RNA polymerase III regulatory region DNA binding GO:0044445//cytosolic part;GO:0031410//cytoplasmic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005782//peroxisomal matrix;GO:0005739//mitochondrion 540 tr|A8K4A0|A8K4A0_HUMAN cDNA FLJ76497, highly similar to Homo sapiens arylsulfatase B (ARSB), transcript variant 2, mRNA OS=Homo sapiens PE=2 SV=1 51874 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDMWKTISEGSPSPRIELLHNIDPNFVDSSPYWPECSLLL 93 9.4 1 6 6 3 3 1.333 1.251 1.178 4 4 4 - - - 1.254 0.077543536 tr|A8K4A0|A8K4A0_HUMAN 100 0 gi|158255166|dbj|BAF83554.1| unnamed protein product [Homo sapiens] 99.72 0 sp|P15848|ARSB_HUMAN Arylsulfatase B OS=Homo sapiens GN=ARSB PE=1 SV=1 100 0 A8K4A0 A8K4A0_HUMAN cDNA FLJ76497, highly similar to Homo sapiens arylsulfatase B (ARSB), transcript variant 2, mRNA OS=Homo sapiens PE=2 SV=1 STM0035 162 1.00E-39 COG3119 Arylsulfatase A and related enzymes P Inorganic ion transport and metabolism ; K01135|1|0.0|725|mcc:709136|arylsulfatase B [EC:3.1.6.12] GO:0030207//chondroitin sulfate catabolic process;GO:0006644//phospholipid metabolic process;GO:0007417//central nervous system development;GO:0007041//lysosomal transport;GO:0006687//glycosphingolipid metabolic process;GO:0043627//response to estrogen stimulus;GO:0007584//response to nutrient;GO:0005975//carbohydrate metabolic process;GO:0043687//post-translational protein modification;GO:0009268//response to pH;GO:0044281//small molecule metabolic process;GO:0006914//autophagy;GO:0051597//response to methylmercury;GO:0007040//lysosome organization GO:0046872//metal ion binding;GO:0004065//arylsulfatase activity;GO:0003943//N-acetylgalactosamine-4-sulfatase activity GO:0005739//mitochondrion;GO:0043202//lysosomal lumen;GO:0005788//endoplasmic reticulum lumen;GO:0005791//rough endoplasmic reticulum;GO:0005794//Golgi apparatus 541 sp|Q15149|PLEC_HUMAN Plectin OS=Homo sapiens GN=PLEC PE=1 SV=3 608600 MVAGMLMPRDQLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMASLRARGLVRETFAWCHFYWYLTNEGIAHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRTPHVQAVQGPLGSPPKRGPLPTEEQRVYRRKELEEVSPETPVVPATTQRTLARPGPEPAPATDERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVPDVQDGVRANELQLRWQEYRELVLLLLQWMRHHTAAFEERRFPSSFEEIEILWSQFLKFKEMELPAKEADKNRSKGIYQSLEGAVQAGQLKVPPGYHPLDVEKEWGKLHVAILEREKQLRSEFERLECLQRIVTKLQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPATQVAQVTLQSVQRRPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFRAKIERARSDEGQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLKPRHPAHPMRGRLPLLAVCDYKQVEVTVHKGDECQLVGPAQPSHWKVLSSSGSEAAVPSVCFLVPPPNQEAQEAVTRLEAQHQALVTLWHQLHVDMKSLLAWQSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGSSASLGGPESAVA 3968 18 - 240 240 70 70 0.794 0.823 0.698 153 156 149 - - - 0.771666667 0.065424256 sp|Q15149|PLEC_HUMAN 100 0 gi|41322908|ref|NP_958781.1| plectin isoform 1e [Homo sapiens] >gi|40849934|gb|AAR95679.1| plectin 3 [Homo sapiens] 100 5.00E-91 sp|Q15149|PLEC_HUMAN Plectin OS=Homo sapiens GN=PLEC PE=1 SV=3 100 0 Q96IE3 Q96IE3_HUMAN Similar to plectin 1, intermediate filament binding protein, 500kD (Fragment) OS=Homo sapiens PE=2 SV=1 SPAC15A10.08 182 2.00E-44 COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) Z Cytoskeleton ; K10388|1|0.0|3958|hsa:5339|plectin GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0031581//hemidesmosome assembly GO:0008307//structural constituent of muscle;GO:0003779//actin binding;GO:0030506//ankyrin binding GO:0030056//hemidesmosome;GO:0043034//costamere;GO:0042383//sarcolemma;GO:0016528//sarcoplasm;GO:0005925//focal adhesion;GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol 542 sp|Q02388|CO7A1_HUMAN Collagen alpha-1(VII) chain OS=Homo sapiens GN=COL7A1 PE=1 SV=2 324606 MTLRLLVAALCAGILAEAPRVRAQHRERVTCTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLARPGVPKVCILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAHSLLVAWRSVPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGATQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGASGFRISWSTGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPGATGYRVSWHSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATAYRLAWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQGFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPVCPRGLADVVFLPHATQDNAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLPSYAADTAGSQLHAVPVLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEAPWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRCPPRVVQSQGTGTAQD 62 1.3 - 3 3 3 3 0.804 2.671 1.341 2 2 2 - - - 1.605333333 0.961158849 sp|Q02388|CO7A1_HUMAN 100 2.00E-28 gi|62088870|dbj|BAD92882.1| alpha 1 type VII collagen precursor variant [Homo sapiens] 100 0 sp|Q02388|CO7A1_HUMAN Collagen alpha-1(VII) chain OS=Homo sapiens GN=COL7A1 PE=1 SV=2 100 5.00E-28 Q59F16 Q59F16_HUMAN Alpha 1 type VII collagen variant (Fragment) OS=Homo sapiens PE=2 SV=1 - - - - - - - K08132|1|7e-86|321|bta:359712|collagen, type XII, alpha GO:0008544//epidermis development;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding GO:0005788//endoplasmic reticulum lumen;GO:0005590//collagen type VII;GO:0005604//basement membrane 543 sp|P16152|CBR1_HUMAN Carbonyl reductase [NADPH] 1 OS=Homo sapiens GN=CBR1 PE=1 SV=3 36421 MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSPEEGAETPVYLALLPPDAEGPHGQFVSEKRVEQW 498 39.4 - 22 22 8 8 0.934 1.01 0.767 16 17 13 - - * 0.903666667 0.124307415 sp|P16152|CBR1_HUMAN 100 6.00E-161 gi|66360348|pdb|1WMA|A Chain A, Crystal Structure Of Human Cbr1 In Complex With Hydroxy-pp >gi|209870395|pdb|3BHI|A Chain A, Crystal Structure Of Human Carbonyl Reductase 1 In Complex With Nadp >gi|209870396|pdb|3BHJ|A Chain A, Crystal Structure Of Human Carbonyl Reductase 1 In Complex With Glutathione >gi|209870397|pdb|3BHM|A Chain A, Crystal Structure Of Human Carbonyl Reductase 1 In Complex With S-Hydroxymethylglutathione 100 1.00E-162 sp|P16152|CBR1_HUMAN Carbonyl reductase [NADPH] 1 OS=Homo sapiens GN=CBR1 PE=1 SV=3 100 4.00E-71 A8MTM1 A8MTM1_HUMAN Carbonyl reductase [NADPH] 1 OS=Homo sapiens GN=CBR1 PE=4 SV=1 all0352 136 4.00E-32 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) IQR Lipid transport and metabolism ; Secondary metabolites biosynthesis, transport and catabolism ; General function prediction only ; K00079|1|1e-162|572|ptr:473983|carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197] GO:0042373//vitamin K metabolic process;GO:0017144//drug metabolic process;GO:0055114//oxidation-reduction process GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0004090//carbonyl reductase (NADPH) activity;GO:0047021//15-hydroxyprostaglandin dehydrogenase (NADP+) activity;GO:0050221//prostaglandin-E2 9-reductase activity;GO:0000166//nucleotide binding GO:0005737//cytoplasm 544 sp|Q16270|IBP7_HUMAN Insulin-like growth factor-binding protein 7 OS=Homo sapiens GN=IGFBP7 PE=1 SV=1 35005 MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGEGAEL 3394 37.2 - 134 134 8 8 0.518 0.34 0.437 103 103 101 - * - 0.431666667 0.08911977 sp|Q16270|IBP7_HUMAN 100 2.00E-59 gi|470613958|ref|XP_004316499.1| PREDICTED: insulin-like growth factor-binding protein 7-like [Tursiops truncatus] 100 1.00E-89 sp|Q16270|IBP7_HUMAN Insulin-like growth factor-binding protein 7 OS=Homo sapiens GN=IGFBP7 PE=1 SV=1 100 5.00E-88 G1RCG4 G1RCG4_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=IGFBP7 PE=4 SV=1 - - - - - - - K08785|1|3e-07|56.2|mdo:100019928|HtrA serine peptidase 3 [EC:3.4.21.-]!K08784|2|1e-06|54.3|xtr:780187|HtrA serine peptidase 1 [EC:3.4.21.-] GO:0048839//inner ear development;GO:0008285//negative regulation of cell proliferation;GO:0001558//regulation of cell growth;GO:0007155//cell adhesion GO:0005520//insulin-like growth factor binding GO:0005615//extracellular space;GO:0031012//extracellular matrix 545 tr|D3DTX7|D3DTX7_HUMAN Collagen, type I, alpha 1, isoform CRA_a OS=Homo sapiens GN=COL1A1 PE=4 SV=1 96704 MGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSGEYWIDPNQGCNLDAIKVFCNMETGETCVYPTQPSVAQKNWYISKNPKDKRHVWFGESMTDGFQFEYGGQGSDPADVAIQLTFLRLMSTEASQNITYHCKNSVAYMDQQTGNLKKALLLQGSNEIEIRAEGNSRFTYSVTVDGCTSHTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAPDQEFGFDVGPVCFL 10161 51.2 - 321 26 26 2 0.879 0.853 0.676 25 24 24 * - - 0.802666667 0.110464172 tr|D3DTX7|D3DTX7_HUMAN 100 6.00E-32 gi|426347471|ref|XP_004041373.1| PREDICTED: collagen alpha-1(I) chain isoform 1 [Gorilla gorilla gorilla] 100 5.00E-22 sp|P02452|CO1A1_HUMAN Collagen alpha-1(I) chain OS=Homo sapiens GN=COL1A1 PE=1 SV=5 100 1.00E-20 F6S739 F6S739_CALJA Uncharacterized protein OS=Callithrix jacchus GN=COL1A1 PE=4 SV=1 - - - - - - - K06236|1|2e-159|563|hsa:1277|collagen, type I/II/III/V/XI, alpha GO:0010812//negative regulation of cell-substrate adhesion;GO:0007601//visual perception;GO:0043434//response to peptide hormone stimulus;GO:0007411//axon guidance;GO:0070208//protein heterotrimerization;GO:0042542//response to hydrogen peroxide;GO:0001957//intramembranous ossification;GO:0071230//cellular response to amino acid stimulus;GO:0034505//tooth mineralization;GO:0015031//protein transport;GO:0030199//collagen fibril organization;GO:0007605//sensory perception of sound;GO:0001958//endochondral ossification;GO:0030168//platelet activation;GO:0031960//response to corticosteroid stimulus;GO:0032964//collagen biosynthetic process;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0060346//bone trabecula formation;GO:0048706//embryonic skeletal system development;GO:0050900//leukocyte migration;GO:0001649//osteoblast differentiation;GO:0090263//positive regulation of canonical Wnt receptor signaling pathway;GO:0043589//skin morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0060325//face morphogenesis;GO:0030335//positive regulation of cell migration;GO:0051591//response to cAMP;GO:0045893//positive regulation of transcription, DNA-dependent;GO:0071363//cellular response to growth factor stimulus;GO:0034504//protein localization to nucleus;GO:0001568//blood vessel development;GO:0071260//cellular response to mechanical stimulus;GO:0060351//cartilage development involved in endochondral bone morphogenesis GO:0048407//platelet-derived growth factor binding;GO:0005201//extracellular matrix structural constituent;GO:0042802//identical protein binding GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005584//collagen type I 546 sp|P00734|THRB_HUMAN Prothrombin OS=Homo sapiens GN=F2 PE=1 SV=2 80601 MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE 810 30.4 - 72 72 15 15 0.786 2.025 0.871 39 27 31 * - - 1.227333333 0.692105724 sp|P00734|THRB_HUMAN 100 9.00E-171 gi|11514286|pdb|1D6W|A Chain A, Structure Of Thrombin Complexed With Selective Non-Electrophilic Inhibitors Having Cyclohexyl Moieties At P1 >gi|14278416|pdb|1G37|A Chain A, Crystal Structure Of Human Alpha-thrombin Complexed With Bch-10556 And Exosite-directed Peptide 100 0 sp|P00734|THRB_HUMAN Prothrombin OS=Homo sapiens GN=F2 PE=1 SV=2 99.68 0 C9JV37 C9JV37_HUMAN Prothrombin (Fragment) OS=Homo sapiens GN=F2 PE=4 SV=1 VC1649 107 5.00E-23 COG5640 Secreted trypsin-like serine protease O Posttranslational modification, protein turnover, chaperones ; K01313|1|0.0|1301|hsa:2147|coagulation factor II (thrombin) [EC:3.4.21.5] GO:0007597//blood coagulation, intrinsic pathway;GO:0048712//negative regulation of astrocyte differentiation;GO:0008284//positive regulation of cell proliferation;GO:0043687//post-translational protein modification;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0010544//negative regulation of platelet activation;GO:0045861//negative regulation of proteolysis;GO:0051918//negative regulation of fibrinolysis;GO:1900738//positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0006953//acute-phase response;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0001934//positive regulation of protein phosphorylation;GO:0050900//leukocyte migration;GO:0030307//positive regulation of cell growth;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0008360//regulation of cell shape;GO:0014068//positive regulation of phosphatidylinositol 3-kinase cascade;GO:0032967//positive regulation of collagen biosynthetic process GO:0008083//growth factor activity;GO:0070053//thrombospondin receptor activity;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005796//Golgi lumen 547 sp|Q9UHL4|DPP2_HUMAN Dipeptidyl peptidase 2 OS=Homo sapiens GN=DPP7 PE=1 SV=3 57805 MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL 188 13.6 - 12 12 6 6 1.893 1.914 1.82 8 8 8 * * * 1.875666667 0.049338964 sp|Q9UHL4|DPP2_HUMAN 100 0 gi|261278872|pdb|3JYH|A Chain A, Human Dipeptidyl Peptidase Dpp7 >gi|261278873|pdb|3JYH|B Chain B, Human Dipeptidyl Peptidase Dpp7 >gi|261278874|pdb|3JYH|C Chain C, Human Dipeptidyl Peptidase Dpp7 >gi|261278875|pdb|3JYH|D Chain D, Human Dipeptidyl Peptidase Dpp7 >gi|301015979|pdb|3N0T|A Chain A, Human Dipeptidil Peptidase Dpp7 Complexed With Inhibitor Gsk237826a >gi|301015980|pdb|3N0T|B Chain B, Human Dipeptidil Peptidase Dpp7 Complexed With Inhibitor Gsk237826a >gi|301015981|pdb|3N0T|C Chain C, Human Dipeptidil Peptidase Dpp7 Complexed With Inhibitor Gsk237826a >gi|301015982|pdb|3N0T|D Chain D, Human Dipeptidil Peptidase Dpp7 Complexed With Inhibitor Gsk237826a 100 0 sp|Q9UHL4|DPP2_HUMAN Dipeptidyl peptidase 2 OS=Homo sapiens GN=DPP7 PE=1 SV=3 100 2.00E-66 B4DPD6 B4DPD6_HUMAN cDNA FLJ56922, highly similar to Dipeptidyl-peptidase 2 (EC 3.4.14.2) OS=Homo sapiens PE=2 SV=1 - - - - - - - K01276|1|0.0|917|hsa:29952|dipeptidyl-peptidase II [EC:3.4.14.2] GO:0006508//proteolysis GO:0008239//dipeptidyl-peptidase activity;GO:0004177//aminopeptidase activity;GO:0008236//serine-type peptidase activity GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005764//lysosome;GO:0005576//extracellular region;GO:0005829//cytosol 548 sp|Q16394|EXT1_HUMAN Exostosin-1 OS=Homo sapiens GN=EXT1 PE=1 SV=2 101239 MQAKKRYFILLSAGSCLALLFYFGGLQFRASRSHSRREEHSGRNGLHHPSPDHFWPRFPDALRPFVPWDQLENEDSSVHISPRQKRDANSSIYKGKKCRMESCFDFTLCKKNGFKVYVYPQQKGEKIAESYQNILAAIEGSRFYTSDPSQACLFVLSLDTLDRDQLSPQYVHNLRSKVQSLHLWNNGRNHLIFNLYSGTWPDYTEDVGFDIGQAMLAKASISTENFRPNFDVSIPLFSKDHPRTGGERGFLKFNTIPPLRKYMLVFKGKRYLTGIGSDTRNALYHVHNGEDVVLLTTCKHGKDWQKHKDSRCDRDNTEYEKYDYREMLHNATFCLVPRGRRLGSFRFLEALQAACVPVMLSNGWELPFSEVINWNQAAVIGDERLLLQIPSTIRSIHQDKILALRQQTQFLWEAYFSSVEKIVLTTLEIIQDRIFKHISRNSLIWNKHPGGLFVLPQYSSYLGDFPYYYANLGLKPPSKFTAVIHAVTPLVSQSQPVLKLLVAAAKSQYCAQIIVLWNCDKPLPAKHRWPATAVPVVVIEGESKVMSSRFLPYDNIITDAVLSLDEDTVLSTTEVDFAFTVWQSFPERIVGYPARSHFWDNSKERWGYTSKWTNDYSMVLTGAAIYHKYYHYLYSHYLPASLKNMVDQLANCEDILMNFLVSAVTKLPPIKVTQKKQYKETMMGQTSRASRWADPDHFAQRQSCMNTFASWFGYMPLIHSQMRLDPVLFKDQVSILRKKYRDIERL 149 8 - 16 16 5 5 0.874 0.585 1.16 7 6 6 - - - 0.873 0.287501304 sp|Q16394|EXT1_HUMAN 100 0 gi|298108449|gb|ADI56520.1| multiple exostoses 1 [Homo sapiens] 100 0 sp|Q16394|EXT1_HUMAN Exostosin-1 OS=Homo sapiens GN=EXT1 PE=1 SV=2 100 4.00E-115 H9F146 H9F146_MACMU Exostosin-1 (Fragment) OS=Macaca mulatta GN=EXT1 PE=2 SV=1 - - - - - - - K02366|1|0.0|1501|mcc:701488|glucuronyl/N-acetylglucosaminyl transferase EXT1 [EC:2.4.1.224 2.4.1.225] GO:0007411//axon guidance;GO:0007492//endoderm development;GO:0007369//gastrulation;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0007498//mesoderm development;GO:0001503//ossification;GO:0006024//glycosaminoglycan biosynthetic process;GO:0006486//protein glycosylation;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0021772//olfactory bulb development;GO:0072498//embryonic skeletal joint development GO:0046982//protein heterodimerization activity;GO:0050509//N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity;GO:0050508//glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0042803//protein homodimerization activity;GO:0042328//heparan sulfate N-acetylglucosaminyltransferase activity GO:0000139//Golgi membrane;GO:0030176//integral to endoplasmic reticulum membrane 549 tr|J3KQJ1|J3KQJ1_HUMAN Sulfatase-modifying factor 2 OS=Homo sapiens GN=SUMF2 PE=1 SV=1 40330 MRAHAQRGRGCTRRSAAVLMARHGLPLLPLLSLLVGAWLKLGNGQATSMVQLQGGRFLMGTNSPDSRDGDGPVREATVKPFAIDIFPVTNKDFRDFVREKKYRTEAEMFGWSFVFEDFVSDELRNKATQPMKSVLWWLPVEKAFWRQPAGPGSGIRERLEHPVLHVSWNDARAYCAWRGKRLPTEEEWEFAARGGLKGQVYPWGNWFQPNRTNLWQGKFPKGDKAEDGFHGVSPVNAFPAQNNYGLYDLLGNVWEWTASPYQAAEQDMRVLRGASWIDTADGSANHRARVTTRMGNTPDSASDNLGFRCAADAGRPPGEL 64 8.4 10 3 3 2 2 0.772 0.871 0.944 2 2 2 * - - 0.862333333 0.086326898 tr|J3KQJ1|J3KQJ1_HUMAN 100 8.00E-132 gi|12652935|gb|AAH00224.1| SUMF2 protein [Homo sapiens] 100 2.00E-170 sp|Q8NBJ7|SUMF2_HUMAN Sulfatase-modifying factor 2 OS=Homo sapiens GN=SUMF2 PE=1 SV=2 100 5.00E-62 F8WEX5 F8WEX5_HUMAN Sulfatase-modifying factor 2 OS=Homo sapiens GN=SUMF2 PE=4 SV=1 mll5466 167 2.00E-41 COG1262 Uncharacterized conserved protein S Function unknown ; K13444|1|6e-74|278|hmg:100198082|sulfatase modifying factor 1 GO:0043687//post-translational protein modification GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity GO:0005788//endoplasmic reticulum lumen 550 tr|B5MCX3|B5MCX3_HUMAN Septin-2 OS=Homo sapiens GN=SEPT2 PE=1 SV=1 44142 MVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGLNRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLITHMQDLQEVTQDLHYENFRSERLKRGGRKVENEDMNKDQILLEKEAELRRMQEMIARMQAQMQMQMQGGDGDGGALGHHV 113 8.7 2 7 7 2 2 1.216 1.014 1.001 4 4 4 - - - 1.077 0.120552893 tr|B5MCX3|B5MCX3_HUMAN 100 3.00E-168 gi|1040689|dbj|BAA05893.1| Human Diff6,H5,CDC10 homologue [Homo sapiens] 100 3.00E-169 sp|Q15019|SEPT2_HUMAN Septin-2 OS=Homo sapiens GN=SEPT2 PE=1 SV=1 100 9.00E-168 G3S8Y7 G3S8Y7_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=SEPT2 PE=3 SV=1 SPAC4F10.11 244 2.00E-64 COG5019 Septin family protein DZ Cell cycle control, cell division, chromosome partitioning ; Cytoskeleton ; K04557|1|1e-103|376|xtr:100125069|peanut-like protein 1 (cell division control related protein 1) GO:0006184//GTP catabolic process;GO:0031175//neuron projection development;GO:0051258//protein polymerization;GO:0007067//mitosis;GO:0032880//regulation of protein localization;GO:0007224//smoothened signaling pathway;GO:0002036//regulation of L-glutamate transport;GO:0050790//regulation of catalytic activity;GO:0042384//cilium assembly;GO:0000910//cytokinesis GO:0005525//GTP binding;GO:0042802//identical protein binding;GO:0003924//GTPase activity;GO:0030234//enzyme regulator activity;GO:0032947//protein complex scaffold GO:0000777//condensed chromosome kinetochore;GO:0060170//cilium membrane;GO:0005730//nucleolus;GO:0009986//cell surface;GO:0000145//exocyst;GO:0032154//cleavage furrow;GO:0030496//midbody;GO:0048471//perinuclear region of cytoplasm;GO:0005876//spindle microtubule;GO:0031105//septin complex;GO:0045202//synapse;GO:0005826//actomyosin contractile ring 551 tr|A0A024R877|A0A024R877_HUMAN Delta-aminolevulinic acid dehydratase OS=Homo sapiens GN=ALAD PE=3 SV=1 41673 MPLCPLAHAMQPQSVLHSGYFHPLLRAWQTATTTLNASNLIYPIFVTDVPDDIQPITSLPGVARYGVKRLEEMLRPLVEEGLRCVLIFGVPSRVPKDERGSAADSEESPAIEAIHLLRKTFPNLLVACDVCLCPYTSHGHCGLLSENGAFRAEESRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKEALMAHGLGNRVSVMSYSAKFASCFYGPFRDAAKSSPAFGDRRCYQLPPGARGLALRAVDRDVREGADMLMVKPGMPYLDIVREVKDKHPDLPLAVYHVSGEFAMLWHGAQAGAFDLKAAVLEAMTAFRRAGADIIITYYTPQLLQWLKEE 133 11.8 3 7 7 3 3 1.039 0.732 1.215 4 5 4 - * - 0.995333333 0.244442904 tr|A0A024R877|A0A024R877_HUMAN 100 0 gi|52632415|gb|AAH00977.3| Aminolevulinate, delta-, dehydratase [Homo sapiens] >gi|119607785|gb|EAW87379.1| aminolevulinate, delta-, dehydratase, isoform CRA_a [Homo sapiens] >gi|119607786|gb|EAW87380.1| aminolevulinate, delta-, dehydratase, isoform CRA_a [Homo sapiens] 100 0 sp|P13716|HEM2_HUMAN Delta-aminolevulinic acid dehydratase OS=Homo sapiens GN=ALAD PE=1 SV=1 99.7 0 H2QXQ8 H2QXQ8_PANTR Delta-aminolevulinic acid dehydratase OS=Pan troglodytes GN=ENSG00000148218 PE=3 SV=1 SPAC1805.06c 363 2.00E-100 COG0113 Delta-aminolevulinic acid dehydratase H Coenzyme transport and metabolism ; K01698|1|0.0|688|mcc:705193|porphobilinogen synthase [EC:4.2.1.24] GO:0044281//small molecule metabolic process;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0051260//protein homooligomerization GO:0042802//identical protein binding;GO:0032791//lead ion binding;GO:0008270//zinc ion binding;GO:0004655//porphobilinogen synthase activity GO:0005829//cytosol 552 sp|O75369|FLNB_HUMAN Filamin-B OS=Homo sapiens GN=FLNB PE=1 SV=2 333089 MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGKAPLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFNSPLPGDAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVLQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP 1068 14.7 - 72 39 30 24 1.069 1.302 0.964 24 24 23 - - - 1.111666667 0.172992293 sp|O75369|FLNB_HUMAN 100 0 gi|62089364|dbj|BAD93126.1| filamin B, beta (actin binding protein 278) variant [Homo sapiens] 100 0 sp|O75369|FLNB_HUMAN Filamin-B OS=Homo sapiens GN=FLNB PE=1 SV=2 99.62 0 H2R1I3 H2R1I3_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000136068 PE=4 SV=1 ECU09g0290 138 1.00E-31 COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) Z Cytoskeleton ; K04437|1|0.0|5170|hsa:2317|filamin GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0007517//muscle organ development;GO:0019221//cytokine-mediated signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0030154//cell differentiation GO:0042802//identical protein binding;GO:0003779//actin binding GO:0005829//cytosol;GO:0030018//Z disc;GO:0016021//integral to membrane;GO:0005938//cell cortex;GO:0015629//actin cytoskeleton;GO:0005634//nucleus;GO:0005886//plasma membrane 553 sp|P09211|GSTP1_HUMAN Glutathione S-transferase P OS=Homo sapiens GN=GSTP1 PE=1 SV=2 >tr|V9HWE9|V9HWE9_HUMAN Epididymis secretory protein Li 22 OS=Homo sapiens GN=HEL-S-22 PE=2 SV=1 27524 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ 684 49 - 42 42 8 8 0.852 1.146 1.065 26 26 26 - - - 1.021 0.151858487 sp|P09211|GSTP1_HUMAN 100 1.00E-119 gi|4504183|ref|NP_000843.1| glutathione S-transferase P [Homo sapiens] >gi|121746|sp|P09211.2|GSTP1_HUMAN RecName: Full=Glutathione S-transferase P; AltName: Full=GST class-pi; AltName: Full=GSTP1-1 >gi|4389047|pdb|12GS|A Chain A, Glutathione S-transferase Complexed With S-nonyl-glutathione >gi|4389048|pdb|12GS|B Chain B, Glutathione S-transferase Complexed With S-nonyl-glutathione >gi|4389051|pdb|13GS|A Chain A, Glutathione S-Transferase Complexed With Sulfasalazine >gi|4389052|pdb|13GS|B Chain B, Glutathione S-Transferase Complexed With Sulfasalazine >gi|4389404|pdb|11GS|A Chain A, Glutathione S-Transferase Complexed With Ethacrynic Acid-Glutathione Conjugate (Form Ii) >gi|4389405|pdb|11GS|B Chain B, Glutathione S-Transferase Complexed With Ethacrynic Acid-Glutathione Conjugate (Form Ii) >gi|4389406|pdb|14GS|A Chain A, Glutathione S-Transferase P1-1 Apo Form 1 >gi|4389407|pdb|14GS|B Chain B, Glutathione S-Transferase P1-1 Apo Form 1 >gi|4389412|pdb|16GS|A Chain A, Glutathione S-Transferase P1-1 Apo Form 3 >gi|4389413|pdb|16GS|B Chain B, Glutathione S-Transferase P1-1 Apo Form 3 >gi|4389414|pdb|18GS|A Chain A, Glutathione S-Transferase P1-1 Complexed With 1-(S- Glutathionyl)-2,4-Dinitrobenzene >gi|4389415|pdb|18GS|B Chain B, Glutathione S-Transferase P1-1 Complexed With 1-(S- Glutathionyl)-2,4-Dinitrobenzene >gi|5822521|pdb|3PGT|A Chain A, Crystal Structure Of Hgstp1-1[i104] Complexed With The Gsh Conjugate Of (+)-Anti-Bpde >gi|5822522|pdb|3PGT|B Chain B, Crystal Structure Of Hgstp1-1[i104] Complexed With The Gsh Conjugate Of (+)-Anti-Bpde >gi|109157106|pdb|2A2R|A Chain A, Crystal Structure Of Glutathione Transferase Pi In Complex With S-Nitrosoglutathione >gi|109157107|pdb|2A2R|B Chain B, Crystal Structure Of Glutathione Transferase Pi In Complex With S-Nitrosoglutathione >gi|109157108|pdb|2A2S|A Chain A, Crystal Structure Of Human Glutathione Transferase In Complex With S-Nitrosoglutathione In The Absence Of Reducing Agent >gi|109157109|pdb|2A2S|B Chain B, Crystal Structure Of Human Glutathione Transferase In Complex With S-Nitrosoglutathione In The Absence Of Reducing Agent >gi|227343722|pdb|3DD3|A Chain A, Crystal Structure Of The Glutathione Transferase Pi Enzyme In Complex With The Bifunctional Inhibitor, Etharapta >gi|227343723|pdb|3DD3|B Chain B, Crystal Structure Of The Glutathione Transferase Pi Enzyme In Complex With The Bifunctional Inhibitor, Etharapta >gi|227343729|pdb|3DGQ|A Chain A, Crystal Structure Of The Glutathione Transferase Pi Enzyme I With The Bifunctional Inhibitor, Etharapta >gi|227343730|pdb|3DGQ|B Chain B, Crystal Structure Of The Glutathione Transferase Pi Enzyme I With The Bifunctional Inhibitor, Etharapta >gi|332639672|pdb|3N9J|A Chain A, Structure Of Human Glutathione Transferase Pi Class In Complex With Ethacraplatin >gi|332639673|pdb|3N9J|B Chain B, Structure Of Human Glutathione Transferase Pi Class In Complex With Ethacraplatin >gi|579940|emb|CAA30847.1| gst-pi protein [Homo sapiens] >gi|598158|gb|AAA56823.1| glutathione S-transferase-pi [Homo sapiens] >gi|763405|gb|AAA64919.1| glutathione S-transferase [Homo sapiens] >gi|32187525|gb|AAP72967.1| glutathione S-transferase pi [Homo sapiens] >gi|47496669|emb|CAG29357.1| GSTP1 [Homo sapiens] >gi|54696760|gb|AAV38752.1| glutathione S-transferase pi [Homo sapiens] >gi|54696762|gb|AAV38753.1| glutathione S-transferase pi [Homo sapiens] >gi|119595055|gb|EAW74649.1| glutathione S-transferase pi, isoform CRA_b [Homo sapiens] 100 2.00E-120 sp|P09211|GSTP1_HUMAN Glutathione S-transferase P OS=Homo sapiens GN=GSTP1 PE=1 SV=2 100 1.00E-81 C7DJS1 C7DJS1_HUMAN Glutathione S-transferase pi (Fragment) OS=Homo sapiens GN=GSTP1 PE=2 SV=1 SMa2319 55.5 6.00E-08 COG0625 Glutathione S-transferase O Posttranslational modification, protein turnover, chaperones ; K00799|1|2e-120|431|hsa:2950|glutathione S-transferase [EC:2.5.1.18] GO:0035732//nitric oxide storage;GO:0007417//central nervous system development;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0035726//common myeloid progenitor cell proliferation;GO:0032930//positive regulation of superoxide anion generation;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB cascade;GO:0000302//response to reactive oxygen species;GO:0032691//negative regulation of interleukin-1 beta production;GO:0071638//negative regulation of monocyte chemotactic protein-1 production;GO:0006805//xenobiotic metabolic process;GO:0002674//negative regulation of acute inflammatory response;GO:0032720//negative regulation of tumor necrosis factor production;GO:0006749//glutathione metabolic process;GO:0051771//negative regulation of nitric-oxide synthase biosynthetic process;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0043508//negative regulation of JUN kinase activity;GO:0048147//negative regulation of fibroblast proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:0070664//negative regulation of leukocyte proliferation;GO:0060547//negative regulation of necrotic cell death GO:0019207//kinase regulator activity;GO:0070026//nitric oxide binding;GO:0035731//dinitrosyl-iron complex binding;GO:0035730//S-nitrosoglutathione binding;GO:0008432//JUN kinase binding;GO:0004364//glutathione transferase activity GO:0005829//cytosol;GO:0005634//nucleus;GO:0097057//TRAF2-GSTP1 complex;GO:0005739//mitochondrion 554 tr|M0QZH0|M0QZH0_HUMAN Reticulocalbin-3 (Fragment) OS=Homo sapiens GN=RCN3 PE=4 SV=1 21017 FQYDHEAFLGREVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQRHIRDSVSAAWDTYDTDRDGRVGWEELRNATYGHYAPGEEFHDVEDAETYKKMLARDERRFRVADQDGDSMATREELTAFLHPEEFPHMRDIVIALFFSRIYLLTFLLL 166 23.7 1 11 11 3 3 0.649 1.278 0.78 7 7 7 * - - 0.902333333 0.331864932 tr|M0QZH0|M0QZH0_HUMAN 100 1.00E-85 gi|402906330|ref|XP_003915955.1| PREDICTED: reticulocalbin-3 [Papio anubis] 100 2.00E-86 sp|Q96D15|RCN3_HUMAN Reticulocalbin-3 OS=Homo sapiens GN=RCN3 PE=1 SV=1 100 5.00E-85 H2QGV4 H2QGV4_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000142552 PE=4 SV=1 - - - - - - - - - GO:0005509//calcium ion binding;GO:0005515//protein binding GO:0005788//endoplasmic reticulum lumen 555 tr|B4DLV7|B4DLV7_HUMAN cDNA FLJ60299, highly similar to Rab GDP dissociation inhibitor beta OS=Homo sapiens PE=2 SV=1 64050 MSLGKRKPSSFYLANFLGKECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIKNIYKRMTGSEFDFEEMKRKKNDIYGED 804 33 1 52 39 13 9 0.961 0.799 0.93 26 26 27 - * - 0.896666667 0.08599031 tr|B4DLV7|B4DLV7_HUMAN 100 0 gi|6598323|ref|NP_001485.2| rab GDP dissociation inhibitor beta isoform 1 [Homo sapiens] >gi|13638228|sp|P50395.2|GDIB_HUMAN RecName: Full=Rab GDP dissociation inhibitor beta; Short=Rab GDI beta; AltName: Full=Guanosine diphosphate dissociation inhibitor 2; Short=GDI-2 >gi|2853174|emb|CAA73734.1| GDP dissociation inhibitor beta [Homo sapiens] >gi|2853176|emb|CAA73735.1| GDP dissociation inhibitor beta [Homo sapiens] >gi|13477339|gb|AAH05145.1| GDP dissociation inhibitor 2 [Homo sapiens] >gi|30582575|gb|AAP35514.1| GDP dissociation inhibitor 2 [Homo sapiens] >gi|48146263|emb|CAG33354.1| GDI2 [Homo sapiens] >gi|119606837|gb|EAW86431.1| GDP dissociation inhibitor 2, isoform CRA_b [Homo sapiens] >gi|119606838|gb|EAW86432.1| GDP dissociation inhibitor 2, isoform CRA_b [Homo sapiens] >gi|197692291|dbj|BAG70109.1| GDP dissociation inhibitor 2 isoform 1 [Homo sapiens] >gi|197692559|dbj|BAG70243.1| GDP dissociation inhibitor 2 isoform 1 [Homo sapiens] 100 0 sp|P50395|GDIB_HUMAN Rab GDP dissociation inhibitor beta OS=Homo sapiens GN=GDI2 PE=1 SV=2 100 0 G1RL94 G1RL94_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=GDI2 PE=4 SV=1 YER136w 487 1.00E-137 COG5044 RAB proteins geranylgeranyltransferase component A (RAB escort protein) O Posttranslational modification, protein turnover, chaperones ; - GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0015031//protein transport GO:0005097//Rab GTPase activator activity;GO:0005515//protein binding;GO:0005093//Rab GDP-dissociation inhibitor activity GO:0005829//cytosol;GO:0009986//cell surface;GO:0016020//membrane;GO:0005794//Golgi apparatus 556 tr|A0A0A0MTS2|A0A0A0MTS2_HUMAN Glucose-6-phosphate isomerase (Fragment) OS=Homo sapiens GN=GPI PE=4 SV=1 76572 TSGQRPAKRRRKSPAMAALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQREARVQ 490 18.2 2 31 3 8 1 0.744 0.583 0.388 3 3 3 - * * 0.571666667 0.178270394 tr|A0A0A0MTS2|A0A0A0MTS2_HUMAN 100 0 gi|14488680|pdb|1IAT|A Chain A, Crystal Structure Of Human Phosphoglucose IsomeraseNEUROLEUKINAUTOCRINE MOTILITY FACTORMATURATION FACTOR 100 0 sp|P06744|G6PI_HUMAN Glucose-6-phosphate isomerase OS=Homo sapiens GN=GPI PE=1 SV=4 99.23 0 G8F3L1 G8F3L1_MACFA Glucose-6-phosphate isomerase (Fragment) OS=Macaca fascicularis GN=EGM_20016 PE=3 SV=1 YPO3718 746 0 COG0166 Glucose-6-phosphate isomerase G Carbohydrate transport and metabolism ; K01810|1|0.0|1169|hsa:2821|glucose-6-phosphate isomerase [EC:5.3.1.9] GO:0001525//angiogenesis;GO:0006094//gluconeogenesis;GO:0007599//hemostasis;GO:0007611//learning or memory;GO:0006959//humoral immune response;GO:0051156//glucose 6-phosphate metabolic process;GO:0046185//aldehyde catabolic process;GO:0006096//glycolysis;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044281//small molecule metabolic process;GO:0019242//methylglyoxal biosynthetic process;GO:0043524//negative regulation of neuron apoptotic process GO:0004347//glucose-6-phosphate isomerase activity;GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0048029//monosaccharide binding;GO:0016866//intramolecular transferase activity GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane 557 tr|B2R6S5|B2R6S5_HUMAN UMP-CMP kinase OS=Homo sapiens GN=CMPK1 PE=2 SV=1 32569 MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG 83 8.8 4 6 6 2 2 0.434 0.39 0.287 2 2 2 - - * 0.370333333 0.075447554 tr|B2R6S5|B2R6S5_HUMAN 100 1.00E-121 gi|7706497|ref|NP_057392.1| UMP-CMP kinase isoform a [Homo sapiens] >gi|6578133|gb|AAF17709.1|AF070416_1 UMP-CMP kinase [Homo sapiens] >gi|119627274|gb|EAX06869.1| cytidylate kinase, isoform CRA_a [Homo sapiens] >gi|119627276|gb|EAX06871.1| cytidylate kinase, isoform CRA_a [Homo sapiens] 100 7.00E-112 sp|P30085|KCY_HUMAN UMP-CMP kinase OS=Homo sapiens GN=CMPK1 PE=1 SV=3 100 4.00E-121 B2R6S5 B2R6S5_HUMAN Cytidylate kinase, isoform CRA_a OS=Homo sapiens GN=CMPK PE=2 SV=1 YKL024c 191 9.00E-49 COG0563 Adenylate kinase and related kinases F Nucleotide transport and metabolism ; K13800|1|2e-121|434|mcc:710196|UMP-CMP kinase [EC:2.7.4.- 2.7.4.14] GO:0006222//UMP biosynthetic process;GO:0015949//nucleobase-containing small molecule interconversion GO:0016776//phosphotransferase activity, phosphate group as acceptor;GO:0004849//uridine kinase activity;GO:0004127//cytidylate kinase activity;GO:0005524//ATP binding GO:0005829//cytosol;GO:0005634//nucleus 558 tr|A0A024R5M3|A0A024R5M3_HUMAN Cortactin, isoform CRA_c OS=Homo sapiens GN=CTTN PE=4 SV=1 71900 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKEKEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPVYEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ 141 8 2 7 7 3 3 0.616 0.659 0.412 5 6 5 * - * 0.562333333 0.131955801 tr|A0A024R5M3|A0A024R5M3_HUMAN 100 1.00E-28 gi|99032005|pdb|2D1X|A Chain A, The Crystal Structure Of The Cortactin-Sh3 Domain And Amap1- Peptide Complex >gi|99032006|pdb|2D1X|B Chain B, The Crystal Structure Of The Cortactin-Sh3 Domain And Amap1- Peptide Complex >gi|99032007|pdb|2D1X|C Chain C, The Crystal Structure Of The Cortactin-Sh3 Domain And Amap1- Peptide Complex >gi|99032008|pdb|2D1X|D Chain D, The Crystal Structure Of The Cortactin-Sh3 Domain And Amap1- Peptide Complex 93.27 0 sp|Q14247|SRC8_HUMAN Src substrate cortactin OS=Homo sapiens GN=CTTN PE=1 SV=2 100 6.00E-115 H7C314 H7C314_HUMAN Src substrate cortactin (Fragment) OS=Homo sapiens GN=CTTN PE=4 SV=1 - - - - - - - K06106|1|0.0|952|pon:100174046|cortactin GO:0006898//receptor-mediated endocytosis GO:0070064//proline-rich region binding GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0001726//ruffle;GO:0030027//lamellipodium 559 sp|P02452|CO1A1_HUMAN Collagen alpha-1(I) chain OS=Homo sapiens GN=COL1A1 PE=1 SV=5 157527 MFSFVDLRLLLLLAATALLTHGQEEGQVEGQDEDIPPITCVQNGLRYHDRDVWKPEPCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPTGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSGEYWIDPNQGCNLDAIKVFCNMETGETCVYPTQPSVAQKNWYISKNPKDKRHVWFGESMTDGFQFEYGGQGSDPADVAIQLTFLRLMSTEASQNITYHCKNSVAYMDQQTGNLKKALLLQGSNEIEIRAEGNSRFTYSVTVDGCTSHTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAPDQEFGFDVGPVCFL 13163 47.7 - 477 181 39 14 1.318 1.376 1.379 150 154 150 - - * 1.357666667 0.034385074 sp|P02452|CO1A1_HUMAN 100 2.00E-157 gi|62088774|dbj|BAD92834.1| Collagen alpha 1 chain precursor variant [Homo sapiens] 100 3.00E-158 sp|P02452|CO1A1_HUMAN Collagen alpha-1(I) chain OS=Homo sapiens GN=COL1A1 PE=1 SV=5 100 4.00E-20 G1M012 G1M012_AILME Uncharacterized protein OS=Ailuropoda melanoleuca PE=4 SV=1 - - - - - - - K06236|1|3e-158|560|hsa:1277|collagen, type I/II/III/V/XI, alpha GO:0010812//negative regulation of cell-substrate adhesion;GO:0007601//visual perception;GO:0043434//response to peptide hormone stimulus;GO:0007411//axon guidance;GO:0070208//protein heterotrimerization;GO:0042542//response to hydrogen peroxide;GO:0001957//intramembranous ossification;GO:0071230//cellular response to amino acid stimulus;GO:0034505//tooth mineralization;GO:0015031//protein transport;GO:0030199//collagen fibril organization;GO:0007605//sensory perception of sound;GO:0001958//endochondral ossification;GO:0030168//platelet activation;GO:0031960//response to corticosteroid stimulus;GO:0032964//collagen biosynthetic process;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0060346//bone trabecula formation;GO:0048706//embryonic skeletal system development;GO:0050900//leukocyte migration;GO:0001649//osteoblast differentiation;GO:0090263//positive regulation of canonical Wnt receptor signaling pathway;GO:0043589//skin morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0060325//face morphogenesis;GO:0030335//positive regulation of cell migration;GO:0051591//response to cAMP;GO:0045893//positive regulation of transcription, DNA-dependent;GO:0071363//cellular response to growth factor stimulus;GO:0034504//protein localization to nucleus;GO:0001568//blood vessel development;GO:0071260//cellular response to mechanical stimulus;GO:0060351//cartilage development involved in endochondral bone morphogenesis GO:0048407//platelet-derived growth factor binding;GO:0005201//extracellular matrix structural constituent;GO:0042802//identical protein binding GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005584//collagen type I 560 tr|E9LUE6|E9LUE6_HUMAN Sphingomyelin phosphodiesterase OS=Homo sapiens GN=SMPD1 PE=2 SV=1 75092 MPRYGASLRQSCPRSGREQGQDGTAGAPGLLWMGLVLALALALALALSDSRVLWAPAEAHPLSPQGHPARLHRIVPRLRDVFGWGNLTCPICKGLFTAINLGLKKEPNVARVGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGHWDIFSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRGSGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPAGPFDMVYWTGDIPAHDVWHQTRQDQLRALTTVTALVRKFLGPVPVYPAVGNHESTPVNSFPPPFIEGNHSSRWLYEAMAKAWEPWLPAEALRTLRIGGFYALSPYPGLRLISLNMNFCSRENFWLLINSTDPAGQLQWLVGELQAAEDRGDKVHIIGHIPPGHCLKSWSWNYYRIVARYENTLAAQFFGHTHVDEFEVFYDEETLSRPLAVAFLAPSATTYIGLNPGYRVYQIDGNYSRSSHVVLDHETYILNLTQANIPGAIPHWQLLYRARETYGLPNTLPTAWHNLVYRMRGDMQLFQTFWFLYHKGHPPSEPCGTPCRLATLCAQLSARADSPALCRHLMPDGSLPEAQSLWPRPLFC 224 10.3 2 12 12 5 5 1.412 0.866 0.957 8 9 8 * - - 1.078333333 0.292524073 tr|E9LUE6|E9LUE6_HUMAN 100 0 gi|556809|emb|CAA45145.1| acid sphingomyelinase [Homo sapiens] >gi|320091590|gb|ADW08999.1| sphingomyelin phosphodiesterase 1 precursor isoform 1 [Homo sapiens] 99.84 0 sp|P17405|ASM_HUMAN Sphingomyelin phosphodiesterase OS=Homo sapiens GN=SMPD1 PE=1 SV=4 100 0 E9LUE8 E9LUE8_HUMAN Sphingomyelin phosphodiesterase 1 isoform 6 OS=Homo sapiens GN=SMPD1 PE=2 SV=1 - - - - - - - K12350|1|0.0|1190|hsa:6609|sphingomyelin phosphodiesterase [EC:3.1.4.12] GO:0046513//ceramide biosynthetic process;GO:0043407//negative regulation of MAP kinase activity;GO:0006685//sphingomyelin catabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0035307//positive regulation of protein dephosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0042493//response to drug;GO:0044281//small molecule metabolic process;GO:0007399//nervous system development;GO:0023021//termination of signal transduction;GO:0042220//response to cocaine GO:0004767//sphingomyelin phosphodiesterase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds GO:0042599//lamellar body;GO:0005615//extracellular space;GO:0043202//lysosomal lumen 561 tr|B2RCM3|B2RCM3_HUMAN cDNA, FLJ96158, highly similar to Homo sapiens calpain 2, (m/II) large subunit (CAPN2), mRNA OS=Homo sapiens PE=2 SV=1 93356 MAGIAAKLAKDREAAEGLGSHERAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRHEDGEFRMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIQSDGFSIETCKIMVDMLDSDRSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL 108 8.9 2 9 9 5 5 0.898 1.257 0.786 3 3 3 - - - 0.980333333 0.246057581 tr|B2RCM3|B2RCM3_HUMAN 100 4.00E-47 gi|194384212|dbj|BAG64879.1| unnamed protein product [Homo sapiens] 99.43 0 sp|P17655|CAN2_HUMAN Calpain-2 catalytic subunit OS=Homo sapiens GN=CAPN2 PE=1 SV=6 100 0 B2RCM3 B2RCM3_HUMAN cDNA, FLJ96158, highly similar to Homo sapiens calpain 2, (m/II) large subunit (CAPN2), mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K03853|1|0.0|1387|ptr:457765|calpain-2 [EC:3.4.22.53] GO:0001666//response to hypoxia;GO:0006508//proteolysis;GO:0001824//blastocyst development;GO:0007520//myoblast fusion GO:0008092//cytoskeletal protein binding;GO:0005509//calcium ion binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0046982//protein heterodimerization activity GO:0000785//chromatin;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane 562 sp|Q15942|ZYX_HUMAN Zyxin OS=Homo sapiens GN=ZYX PE=1 SV=1 70649 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAPGGSGSQPNQKLGHPEALSAGTGSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARAQT 252 14.5 - 22 22 5 5 0.754 0.77 0.597 13 13 13 * - * 0.707 0.095598117 sp|Q15942|ZYX_HUMAN 100 2.00E-17 gi|386782137|ref|NP_001247977.1| zyxin [Macaca mulatta] 100 2.00E-18 sp|Q15942|ZYX_HUMAN Zyxin OS=Homo sapiens GN=ZYX PE=1 SV=1 100 7.00E-17 G3S1P9 G3S1P9_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=ZYX PE=4 SV=1 - - - - - - - K06273|1|8e-165|580|hsa:7791|zyxin GO:0007267//cell-cell signaling;GO:0007165//signal transduction GO:0005515//protein binding GO:0005913//cell-cell adherens junction;GO:0001725//stress fiber;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0005887//integral to plasma membrane 563 tr|H0YJ31|H0YJ31_HUMAN Fibulin-5 (Fragment) OS=Homo sapiens GN=FBLN5 PE=4 SV=1 19441 XFETGSCSAAQAGVAYLAYVANVKYLGECSNVLKTRDLSRCMCPAENPGCRDQPFTILYRDMDVVSGRSVPADIFQMQATTRYPGAYYIFQIKSGNEGREFYMRQTGPISATLVMTRPIKGPREIQLDLEMITVNTVINFRGSSVIRLRIYVSQYPF 150 22.9 4 13 13 3 3 1.175 2.15 1.963 6 6 6 - * * 1.762666667 0.517451769 tr|H0YJ31|H0YJ31_HUMAN 99.16 9.00E-65 gi|28207929|emb|CAD62618.1| unnamed protein product [Homo sapiens] 99.16 3.00E-65 sp|Q5RC26|FBLN5_PONAB Fibulin-5 OS=Pongo abelii GN=FBLN5 PE=2 SV=1 100 1.00E-86 H0YJ31 H0YJ31_HUMAN Fibulin-5 (Fragment) OS=Homo sapiens GN=FBLN5 PE=4 SV=1 - - - - - - - - GO:0034394//protein localization to cell surface;GO:2000121//regulation of removal of superoxide radicals;GO:0048251//elastic fiber assembly;GO:0007160//cell-matrix adhesion;GO:0007596//blood coagulation GO:0005509//calcium ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0008022//protein C-terminus binding;GO:0005178//integrin binding GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0071953//elastic fiber 564 tr|Q59GB4|Q59GB4_HUMAN Dihydropyrimidinase-like 2 variant (Fragment) OS=Homo sapiens PE=2 SV=1 78636 IDFDSLSVGRGSGQVVAQQRDVAHLGPDPQPPYSRQGRRAGGEPSVESGRKVEIRRASGKEALQNINDQSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG 903 25 1 34 33 10 9 0.956 0.853 0.801 24 24 24 - - - 0.87 0.078885994 tr|Q59GB4|Q59GB4_HUMAN 100 0 gi|347543829|ref|NP_001231533.1| dihydropyrimidinase-related protein 2 isoform 3 [Homo sapiens] 98.6 0 sp|Q16555|DPYL2_HUMAN Dihydropyrimidinase-related protein 2 OS=Homo sapiens GN=DPYSL2 PE=1 SV=1 100 0 B4DR31 B4DR31_HUMAN Dihydropyrimidinase-related protein 2 OS=Homo sapiens GN=DPYSL2 PE=2 SV=1 PA0441 436 8.00E-122 COG0044 Dihydroorotase and related cyclic amidohydrolases F Nucleotide transport and metabolism ; K07528|1|0.0|1268|hsa:1808|dihydropyrimidinase-like 2 GO:0030154//cell differentiation;GO:0006208//pyrimidine nucleobase catabolic process;GO:0007010//cytoskeleton organization;GO:0007399//nervous system development GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0019901//protein kinase binding GO:0030425//dendrite;GO:0030424//axon;GO:0043025//neuronal cell body;GO:0005739//mitochondrion 565 tr|A0A0A0MRJ7|A0A0A0MRJ7_HUMAN Coagulation factor V OS=Homo sapiens GN=F5 PE=4 SV=1 292156 MFPGCPRLWVLVVLGTSWVGWGSQGTEAAQLRQFYVAAQGISWSYRPEPTNSSLNLSVTSFKKIVYREYEPYFKKEKPQSTISGLLGPTLYAEVGDIIKVHFKNKADKPLSIHPQGIRYSKLSEGASYLDHTFPAEKMDDAVAPGREYTYEWSISEDSGPTHDDPPCLTHIYYSHENLIEDFNSGLIGPLLICKKGTLTEGGTQKTFDKQIVLLFAVFDESKSWSQSSSLMYTVNGYVNGTMPDITVCAHDHISWHLLGMSSGPELFSIHFNGQVLEQNHHKVSAITLVSATSTTANMTVGPEGKWIISSLTPKHLQAGMQAYIDIKNCPKKTRNLKKITREQRRHMKRWEYFIAAEEVIWDYAPVIPANMDKKYRSQHLDNFSNQIGKHYKKVMYTQYEDESFTKHTVNPNMKEDGILGPIIRAQVRDTLKIVFKNMASRPYSIYPHGVTFSPYEDEVNSSFTSGRNNTMIRAVQPGETYTYKWNILEFDEPTENDAQCLTRPYYSDVDIMRDIASGLIGLLLICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYLEDNINKFCENPDEVKRDDPKFYESNIMSNFTLSAINGYVPESITTLGFCFDDTVQWHFCSVGTQNEILTIHFTGHSFIYGKRHEDTLTLFPMRGESVTVTMDNVGTWMLTSMNSSPRSKKLRLKFRDVKCIPDDDEDSYEIFEPPESTVMATRKMHDRLEPEDEESDADYDYQNRLAAALGIRSFRNSSLNQEEEEFNLTALALENGTEFVSSNTDIIVGSNYSSPSNISKFTVNNLAEPQKAPSHQQATTAGSPLRHLIGKNSVLNSSTAEHSSPYSEDPIEDPLQPDVTGIRLLSLGAGEFKSQEHAKHKGPKVERDQAAKHRFSWMKLLAHKVGRHLSQDTGSPSGMRPWEDLPSQDTGSPSRMRPWKDPPSDLLLLKQSNSSKILVGRWHLASEKGSYEIIQDTDEDTAVNNWLISPQNASRAWGESTPLANKPGKQSGHPKFPRVRHKSLQVRQDGGKSRLKKSQFLIKTRKKKKEKHTHHAPLSPRTFHPLRSEAYNTFSERRLKHSLVLHKSNETSLPTDLNQTLPSMDFGWIASLPDHNQNSSNDTGQASCPPGLYQTVPPEEHYQTFPIQDPDQMHSTSDPSHRSSSPELSEMLEYDRSHKSFPTDISQMSPSSEHEVWQTVISPDLSQVTLSPELSQTNLSPDLSHTTLSPELIQRNLSPALGQMPISPDLSHTTLSPDLSHTTLSLDLSQTNLSPELSQTNLSPALGQMPLSPDLSHTTLSLDFSQTNLSPELSHMTLSPELSQTNLSPALGQMPISPDLSHTTLSLDFSQTNLSPELSQTNLSPALGQMPLSPDPSHTTLSLDLSQTNLSPELSQTNLSPDLSEMPLFADLSQIPLTPDLDQMTLSPDLGETDLSPNFGQMSLSPDLSQVTLSPDISDTTLLPDLSQISPPPDLDQIFYPSESSQSLLLQEFNESFPYPDLGQMPSPSSPTLNDTFLSKEFNPLVIVGLSKDGTDYIEIIPKEEVQSSEDDYAEIDYVPYDDPYKTDVRTNINSSRDPDNIAAWYLRSNNGNRRNYYIAAEEISWDYSEFVQRETDIEDSDDIPEDTTYKKVVFRKYLDSTFTKRDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDIHSGLIGPLLICQKGILHKDSNMPMDMREFVLLFMTFDEKKSWYYEKKSRSSWRLTSSEMKKSHEFHAINGMIYSLPGLKMYEQEWVRLHLLNIGGSQDIHVVHFHGQTLLENGNKQHQLGVWPLLPGSFKTLEMKASKPGWWLLNTEVGENQRAGMQTPFLIMDRDCRMPMGLSTGIISDSQIKASEFLGYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGIQTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDASTIKENQFDPPIVARYIRISPTRAYNRPTLRLELQGCEVNGCSTPLGMENGKIENKQITASSFKKSWWGDYWEPFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYTIHYSEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSIALRLELFGCDIY 269 3 1 8 8 5 5 1.597 1.238 0.897 6 5 5 * - - 1.244 0.350038569 tr|A0A0A0MRJ7|A0A0A0MRJ7_HUMAN 100 0 gi|194390858|dbj|BAG62188.1| unnamed protein product [Homo sapiens] 99.73 0 sp|P12259|FA5_HUMAN Coagulation factor V OS=Homo sapiens GN=F5 PE=1 SV=4 100 0 B4DU26 B4DU26_HUMAN Coagulation factor V OS=Homo sapiens GN=F5 PE=2 SV=1 - - - - - - - K03902|1|0.0|4384|hsa:2153|coagulation factor V (labile factor) GO:0030168//platelet activation;GO:0007155//cell adhesion;GO:0002576//platelet degranulation;GO:0008015//blood circulation GO:0005507//copper ion binding;GO:0005515//protein binding GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0005886//plasma membrane 566 tr|E9PC71|E9PC71_HUMAN Hippocalcin-like protein 1 OS=Homo sapiens GN=HPCAL1 PE=1 SV=1 24993 MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGSAGWGRGCMCTPR 60 12.6 2 3 3 2 2 0.697 0.583 0.552 2 2 2 * - - 0.610666667 0.076356619 tr|E9PC71|E9PC71_HUMAN 100 2.00E-92 gi|444731687|gb|ELW72036.1| Hippocalcin-like protein 1 [Tupaia chinensis] 100 3.00E-93 sp|Q06AT0|HPCL1_PIG Hippocalcin-like protein 1 OS=Sus scrofa GN=HPCAL1 PE=2 SV=3 100 8.00E-92 F7EJ58 F7EJ58_CALJA Uncharacterized protein OS=Callithrix jacchus GN=LOC100404699 PE=4 SV=1 SPAC18B11.04 219 1.00E-57 COG5126 Ca2+-binding protein (EF-Hand superfamily) TZDR Signal transduction mechanisms ; Cytoskeleton ; Cell cycle control, cell division, chromosome partitioning ; General function prediction only ; K13764|1|9e-49|192|cfa:489500|recoverin GO:0048839//inner ear development GO:0003779//actin binding;GO:0005509//calcium ion binding - 567 tr|B4DPQ0|B4DPQ0_HUMAN Complement C1r subcomponent OS=Homo sapiens GN=C1R PE=2 SV=1 94632 MSVRFRVGREENAQWWLLYLLVPALFCRAGGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKISADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEIIKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRGGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYVDWIKKEMEEED 3075 40.3 3 142 142 18 18 2.454 2.063 3.409 90 90 78 - - - 2.642 0.692413894 tr|B4DPQ0|B4DPQ0_HUMAN 100 0 gi|179644|gb|AAA51851.1| human complement C1r [Homo sapiens] 99.86 0 sp|P00736|C1R_HUMAN Complement C1r subcomponent OS=Homo sapiens GN=C1R PE=1 SV=2 100 0 D3DUT5 D3DUT5_HUMAN Complement C1r subcomponent heavy chain OS=Homo sapiens GN=C1R PE=4 SV=1 VC1649 91.3 6.00E-18 COG5640 Secreted trypsin-like serine protease O Posttranslational modification, protein turnover, chaperones ; K01330|1|0.0|1474|hsa:715|complement component 1, r subcomponent [EC:3.4.21.41] GO:0045087//innate immune response;GO:0006958//complement activation, classical pathway;GO:0006508//proteolysis GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding GO:0005576//extracellular region 568 tr|A0A024QZ34|A0A024QZ34_HUMAN Microfibrillar-associated protein 4, isoform CRA_a OS=Homo sapiens GN=MFAP4 PE=4 SV=1 35430 MGELSPLQRPLATEGTMKAQGVLLKLALLALPLLLLLSTPPCAPQVSGIRGDALERFCLQQPLDCDDIYAQGYQSDGVYLIYPSGPSVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAEEDGYTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGGSHLSYANGINWAQWKGFYYSLKRTEMKIRRA 310 9 2 18 18 2 2 2.542 1.599 2.817 11 11 11 * * * 2.319333333 0.638800699 tr|A0A024QZ34|A0A024QZ34_HUMAN 100 1.00E-153 gi|310923208|ref|NP_001185624.1| microfibril-associated glycoprotein 4 isoform 1 precursor [Homo sapiens] >gi|119571273|gb|EAW50888.1| microfibrillar-associated protein 4, isoform CRA_a [Homo sapiens] >gi|119571275|gb|EAW50890.1| microfibrillar-associated protein 4, isoform CRA_a [Homo sapiens] 100 3.00E-143 sp|P55083|MFAP4_HUMAN Microfibril-associated glycoprotein 4 OS=Homo sapiens GN=MFAP4 PE=1 SV=2 100 4.00E-153 A8MVM2 A8MVM2_HUMAN Microfibril-associated glycoprotein 4 OS=Homo sapiens GN=MFAP4 PE=4 SV=1 - - - - - - - K10104|1|2e-57|222|mdo:100019669|ficolin GO:0007165//signal transduction;GO:0007155//cell adhesion GO:0005102//receptor binding GO:0001527//microfibril 569 sp|P12110|CO6A2_HUMAN Collagen alpha-2(VI) chain OS=Homo sapiens GN=COL6A2 PE=1 SV=4 126136 MLQGTCSVLLLWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQSPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKPQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVAQCTQRPVDIVFLLDGSERLGEQNFHKARRFVEQVARRLTLARRDDDPLNARVALLQFGGPGEQQVAFPLSHNLTAIHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFLTDGVTGNDSLHESAHSMRKQNVVPTVLALGSDVDMDVLTTLSLGDRAAVFHEKDYDSLAQPGFFDRFIRWIC 2448 23.6 - 124 124 17 17 1.52 1.692 1.782 73 75 74 * - * 1.664666667 0.133121498 sp|P12110|CO6A2_HUMAN 100 2.00E-19 gi|30043|emb|CAA29556.1| unnamed protein product [Homo sapiens] 100 0 sp|P12110|CO6A2_HUMAN Collagen alpha-2(VI) chain OS=Homo sapiens GN=COL6A2 PE=1 SV=4 100 6.00E-89 G7P042 G7P042_MACFA Collagen alpha-2(VI) chain (Fragment) OS=Macaca fascicularis GN=EGM_12094 PE=4 SV=1 - - - - - - - K06238|1|0.0|1598|hsa:1292|collagen, type VI, alpha GO:0007411//axon guidance;GO:0009749//response to glucose stimulus;GO:0016337//cell-cell adhesion;GO:0070208//protein heterotrimerization;GO:0030198//extracellular matrix organization GO:0030674//protein binding, bridging;GO:0005201//extracellular matrix structural constituent GO:0043234//protein complex;GO:0005581//collagen;GO:0030133//transport vesicle;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0042383//sarcolemma 570 tr|A0A024RAN2|A0A024RAN2_HUMAN Calpastatin, isoform CRA_a OS=Homo sapiens GN=CAST PE=4 SV=1 118655 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEGSLPDFQQQSLSLGLPWPKMGQFLSSTFLEGSPATVWHDKLCDGERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 178 5.4 17 7 7 3 3 0.959 0.898 0.738 5 5 5 - - * 0.865 0.114135884 tr|A0A024RAN2|A0A024RAN2_HUMAN 100 0 gi|119616470|gb|EAW96064.1| calpastatin, isoform CRA_a [Homo sapiens] >gi|119616472|gb|EAW96066.1| calpastatin, isoform CRA_a [Homo sapiens] 88.34 1.00E-115 sp|P49342|ICAL_CHLAE Calpastatin (Fragment) OS=Chlorocebus aethiops GN=CAST PE=2 SV=1 100 1.00E-10 Q9Y2M4 Q9Y2M4_HUMAN Heart-type calpastatin (Fragment) OS=Homo sapiens PE=2 SV=1 - - - - - - - K04281|1|0.0|900|hsa:831|calpastatin GO:0009303//rRNA transcription;GO:0010951//negative regulation of endopeptidase activity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway GO:0003899//DNA-directed RNA polymerase activity;GO:0010859//calcium-dependent cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding GO:0000120//RNA polymerase I transcription factor complex;GO:0005739//mitochondrion;GO:0005736//DNA-directed RNA polymerase I complex;GO:0005694//chromosome 571 tr|B1AHL2|B1AHL2_HUMAN Fibulin-1 OS=Homo sapiens GN=FBLN1 PE=3 SV=1 88524 MERAAPSRRVPLPLLLLGGLALLAAGVDADVLLEACCADGHRMATHQKDCSLPYATESKECRAVGLASLCQDLNGAWAVWKVGRASQAEGTASARAQRRGMVQEQCCHSQLEELHCATGISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQAQGQSCEYSLMVGYQCGQVFQACCVKSQETGDLDVGGLQETDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKLPLRITYYHLSFPTNIQAPAVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSGVVALTKPVPEPRDLLLTVKMDLSRHGTVSSFVAKLFIFVSAEL 1727 24.7 - 75 2 12 1 1.898 1.389 --- 2 2 1 * - - 1.6435 0.359917352 tr|B1AHL2|B1AHL2_HUMAN 99.8 0 gi|10441928|gb|AAG17241.1|AF217999_1 unknown [Homo sapiens] 96.83 0 sp|Q8MJJ9|FBLN1_CHLAE Fibulin-1 (Fragment) OS=Chlorocebus aethiops GN=FBLN1 PE=1 SV=1 100 0 B1AHL2 B1AHL2_HUMAN Fibulin 1 OS=Homo sapiens GN=FBLN1 PE=4 SV=1 - - - - - - - K08023|1|2e-54|214|mmu:268977|latent transforming growth factor beta binding protein GO:0019048//virus-host interaction GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 572 tr|A0A090N8P3|A0A090N8P3_HUMAN FK506 binding protein 9, 63 kDa OS=Homo sapiens GN=FKBP9 PE=4 SV=1 71686 MAFRGWRPPPPPLLLLLLWVTGQAAPVAGLGSDAELQIERRFVPDECPRTVRSGDFVRYHYVGTFPDGQKFDSSYDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIPPKLAYGSEGVSGVIPPNSVLHFDVLLMDIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVAGLPEGYMFIWNGEVSPNLFEEIDKDGNGEVLLEEFSEYIHAQVASGKGKLAPGFDAELIVKNMFTNQDRNGDGKVTAEEFKLKDQEAKHDEL 147 15.8 2 12 12 7 7 1.296 0.853 1.288 5 6 4 - - - 1.145666667 0.25348833 tr|A0A090N8P3|A0A090N8P3_HUMAN 100 5.00E-100 gi|48735388|gb|AAH72422.1| FKBP9 protein [Homo sapiens] 99.82 0 sp|O95302|FKBP9_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP9 OS=Homo sapiens GN=FKBP9 PE=1 SV=2 100 5.00E-143 B7ZAH5 B7ZAH5_HUMAN cDNA, FLJ79189, highly similar to FK506-binding protein 9 (EC 5.2.1.8) OS=Homo sapiens PE=2 SV=1 YDR519w 100 7.00E-21 COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 O Posttranslational modification, protein turnover, chaperones ; K09575|1|0.0|1142|hsa:11328|FK506-binding protein 9/10 [EC:5.2.1.8] GO:0009749//response to glucose stimulus;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0006458//'de novo' protein folding;GO:0019227//neuronal action potential propagation;GO:0030073//insulin secretion;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0042026//protein refolding;GO:0006939//smooth muscle contraction;GO:0032513//negative regulation of protein phosphatase type 2B activity;GO:0051775//response to redox state;GO:0010459//negative regulation of heart rate;GO:0000413//protein peptidyl-prolyl isomerization;GO:0022417//protein maturation by protein folding;GO:0042098//T cell proliferation GO:0005528//FK506 binding;GO:0005102//receptor binding;GO:0005219//ryanodine-sensitive calcium-release channel activity;GO:0005509//calcium ion binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity GO:0034704//calcium channel complex;GO:0005829//cytosol;GO:0033017//sarcoplasmic reticulum membrane 573 tr|Q6IPN0|Q6IPN0_HUMAN Reticulon OS=Homo sapiens GN=RTN4 PE=2 SV=1 42124 MEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE 350 16.6 2 9 9 3 3 0.535 0.546 0.417 7 7 8 * * * 0.499333333 0.071514567 tr|Q6IPN0|Q6IPN0_HUMAN 100 1.00E-60 gi|444706536|gb|ELW47873.1| Reticulon-4 [Tupaia chinensis] 98.44 3.00E-67 sp|Q9NQC3|RTN4_HUMAN Reticulon-4 OS=Homo sapiens GN=RTN4 PE=1 SV=2 100 2.00E-66 Q4FZ93 Q4FZ93_PANTR RTN4-C OS=Pan troglodytes GN=LOC100609668 PE=2 SV=1 - - - - - - - K00688|1|5e-16|85.9|ame:409267|starch phosphorylase [EC:2.4.1.1] GO:0001525//angiogenesis;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0045665//negative regulation of neuron differentiation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0021801//cerebral cortex radial glia guided migration;GO:0033603//positive regulation of dopamine secretion;GO:0030334//regulation of cell migration;GO:0048679//regulation of axon regeneration;GO:0071786//endoplasmic reticulum tubular network organization;GO:0045687//positive regulation of glial cell differentiation;GO:2000172//regulation of branching morphogenesis of a nerve;GO:0070571//negative regulation of neuron projection regeneration;GO:0030517//negative regulation of axon extension;GO:0007413//axonal fasciculation;GO:0051930//regulation of sensory perception of pain GO:0032403//protein complex binding GO:0043005//neuron projection;GO:0030176//integral to endoplasmic reticulum membrane;GO:0043209//myelin sheath;GO:0005635//nuclear envelope;GO:0043025//neuronal cell body;GO:0043234//protein complex;GO:0005886//plasma membrane 574 tr|A0A024R035|A0A024R035_HUMAN Complement component 9, isoform CRA_a OS=Homo sapiens GN=C9 PE=4 SV=1 76205 MSACWSFAVAICILEISILTAQYTTSYDPELTESSGSASHIDCRMSPWSEWSQCDPCLRQMFRSRSIEVFGQFNGKRCTDAVGDRRQCVPTEPCEDAEDDCGNDFQCSTGRCIKMRLRCNGDNDCGDFSDEDDCESEPRPPCRDRVVEESELARTAGYGINILGMDPLSTPFDNEFYNGLCNRDRDGNTLTYYRRPWNVASLIYETKGEKNFRTEHYEEQIEAFKSIIQEKTSNFNAAISLKFTPTETNKAEQCCEETASSISLHGKGSFRFSYSKNETYQLFLSYSSKKEKMFLHVKGEIHLGRFVMRNRDVVLTTTFVDDIKALPTTYEKGEYFAFLETYGTHYSSSGSLGGLYELIYVLDKASMKRKGVELKDIKRCLGYHLDVSLAFSEISVGAEFNKDDCVKRGEGRAVNITSENLIDDVVSLIRGGTRKYAFELKEKLLRGTVIDVTDFVNWASSINDAPVLISQKLSPIYNLVPVKMKNAHLKKQNLERAIEDYINEFSVRKCHTCQNGGTVILMDGKCLCACPFKFEGIACEISKQKISEGLPALEFPNEK 115 8.2 1 8 8 4 4 0.835 1.952 0.77 6 6 2 - * - 1.185666667 0.664459429 tr|A0A024R035|A0A024R035_HUMAN 100 0 gi|119576390|gb|EAW55986.1| complement component 9, isoform CRA_a [Homo sapiens] >gi|119576391|gb|EAW55987.1| complement component 9, isoform CRA_a [Homo sapiens] 99.82 0 sp|P02748|CO9_HUMAN Complement component C9 OS=Homo sapiens GN=C9 PE=1 SV=2 98.57 0 H2QQT0 H2QQT0_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000113600 PE=4 SV=1 - - - - - - - K04000|1|0.0|1112|hsa:735|complement component 9 GO:0019835//cytolysis;GO:0006917//induction of apoptosis;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0019836//hemolysis by symbiont of host erythrocytes;GO:0007596//blood coagulation - GO:0005579//membrane attack complex;GO:0005576//extracellular region 575 tr|A0A075B6N9|A0A075B6N9_HUMAN Ig mu chain C region (Fragment) OS=Homo sapiens GN=IGHM PE=1 SV=2 57090 GSASAPTLFPLVSCENSPSDTSSVAVGCLAQDFLPDSITFSWKYKNNSDISSTRGFPSVLRGGKYAATSQVLLPSKDVMQGTDEHVVCKVQHPNGNKEKNVPLPVIAELPPKVSVFVPPRDGFFGNPRKSKLICQATGFSPRQIQVSWLREGKQVGSGVTTDQVQAEAKESGPTTYKVTSTLTIKESDWLGQSMFTCRVDHRGLTFQQNASSMCVPDQDTAIRVFAIPPSFASIFLTKSTKLTCLVTDLTTYDSVTISWTRQNGEAVKTHTNISESHPNATFSAVGEASICEDDWNSGERFTCTVTHTDLPSPLKQTISRPKGVALHRPDVYLLPPAREQLNLRESATITCLVTGFSPADVFVQWMQRGQPLSPEKYVTSAPMPEPQAPGRYFAHSILTVSEEEWNTGETYTCVVAHEALPNRVTERTVDKSTGKPTLYNVSLVMSDTAGTCY 1678 23.6 3 80 80 9 9 0.725 2.896 1.216 57 46 42 * - - 1.612333333 1.138472807 tr|A0A075B6N9|A0A075B6N9_HUMAN 100 2.00E-58 gi|55741115|gb|AAV64252.1| immunoglobulin heavy chain [Homo sapiens] 99.56 0 sp|P01871|IGHM_HUMAN Ig mu chain C region OS=Homo sapiens GN=IGHM PE=1 SV=3 99.47 0 Q86TT1 Q86TT1_HUMAN Full-length cDNA clone CS0DD006YL02 of Neuroblastoma of Homo sapiens (human) OS=Homo sapiens PE=2 SV=1 - - - - - - - K06856|1|6e-80|298|xtr:548369|immunoglobulin heavy chain GO:0006955//immune response GO:0003823//antigen binding GO:0005576//extracellular region;GO:0016021//integral to membrane;GO:0005886//plasma membrane 576 tr|Q7Z528|Q7Z528_HUMAN E3-16 OS=Homo sapiens PE=2 SV=1 37003 MVKVTFNSALAQKEAKKDEPKSGEEALIIPPEAVAVDCKDPDDVVRLGQRRAWCWCMCFGLAFMLAGVILGGAYLYKYFALQPDDVYYCGIKYIKDDVILNEPSADAPAALYQTIEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFFIYRLCHDKETYKLQRRETIKGIQKREASNCFAIRHFENKFAVETLICS 222 12.8 2 8 8 3 3 1.183 1.017 0.817 8 8 8 - - - 1.005666667 0.183263017 tr|Q7Z528|Q7Z528_HUMAN 100 5.00E-139 gi|33150540|gb|AAP97148.1|AF086918_1 E3-16 [Homo sapiens] 98.87 4.00E-138 sp|Q5R876|ITM2B_PONAB Integral membrane protein 2B OS=Pongo abelii GN=ITM2B PE=2 SV=1 100 2.00E-138 Q7Z528 Q7Z528_HUMAN E3-16 OS=Homo sapiens PE=2 SV=1 - - - - - - - - GO:0006917//induction of apoptosis;GO:0007399//nervous system development;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process GO:0001540//beta-amyloid binding;GO:0005524//ATP binding GO:0005615//extracellular space;GO:0030660//Golgi-associated vesicle membrane;GO:0031301//integral to organelle membrane;GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0005886//plasma membrane 577 tr|E9PDD2|E9PDD2_HUMAN Vascular cell adhesion protein 1 OS=Homo sapiens GN=VCAM1 PE=4 SV=1 72398 MPGKMVVILGASNILWIMFAASQAFKIETTPESRYLAQIGDSVSLTCSTTGCESPFFSWRTQIDSPLNGKVTNEGTTSTLTMNPVSFGNEHSYLCTATCESRKLEKGIQVEIYSFPKDPEIHLSGPLEAGKPITVKCSVADVYPFDRLEIDLLKGDHLMKSQEFLEDADRKSLETKSLEVTFTPVIEDIGKVLVCRAKLHIDEMDSVPTVRQAVKELQVYISPKNTVISVNPSTKLQEGGSVTMTCSSEGLPAPEIFWSKKLDNGNLQHLSGNATLTLIAMRMEDSGIYVCEGVNLIGKNRKEVELIVQVAPRDTTVLVSPSSILEEGSSVNMTCLSQGFPAPKILWSRQLPNGELQPLSENATLTLISTKMEDSGVYLCEGINQAGRSRKEVELIIQVTPKDIKLTAFPSESVKEGDTVIISCTCGNVPETWIILKKKAETGDTVLKSIDGAYTIRKAQLKDAGVYECESKNKVGSQLRSLTLDVQGRENNKDYFSPELLVLYFASSLIIPAIGMIIYFARKANMKGSYSLVEAQKSKV 70 4.4 2 4 4 2 2 2.348 2.076 2.677 3 3 2 * - - 2.367 0.300950162 tr|E9PDD2|E9PDD2_HUMAN 100 2.00E-22 gi|51476633|emb|CAH18296.1| hypothetical protein [Homo sapiens] 75.66 0 sp|P19320|VCAM1_HUMAN Vascular cell adhesion protein 1 OS=Homo sapiens GN=VCAM1 PE=1 SV=1 100 0 E9PDD2 E9PDD2_HUMAN Vascular cell adhesion protein 1 OS=Homo sapiens GN=VCAM1 PE=4 SV=1 - - - - - - - K06527|1|0.0|817|ssc:396925|vascular cell adhesion molecule 1 GO:0050901//leukocyte tethering or rolling;GO:0071333//cellular response to glucose stimulus;GO:0060710//chorio-allantoic fusion;GO:0002526//acute inflammatory response;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0007507//heart development;GO:0007157//heterophilic cell-cell adhesion;GO:0007568//aging;GO:0030183//B cell differentiation;GO:0042102//positive regulation of T cell proliferation;GO:0022614//membrane to membrane docking;GO:0050776//regulation of immune response;GO:0002544//chronic inflammatory response;GO:0001666//response to hypoxia;GO:0019048//virus-host interaction;GO:0010212//response to ionizing radiation;GO:0007584//response to nutrient GO:0005178//integrin binding;GO:0050839//cell adhesion molecule binding GO:0030175//filopodium;GO:0005615//extracellular space;GO:0005902//microvillus;GO:0016021//integral to membrane;GO:0042383//sarcolemma;GO:0009897//external side of plasma membrane;GO:0045177//apical part of cell;GO:0071065//alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex;GO:0002102//podosome 578 sp|Q9H6X2|ANTR1_HUMAN Anthrax toxin receptor 1 OS=Homo sapiens GN=ANTXR1 PE=1 SV=2 72255 MATAERRALGIGFQWLSLATLVLICAGQGGRREDGGPACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAEESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRVKNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRPSV 78 2.1 5 5 5 1 1 1.834 1.531 1.961 3 3 3 * * - 1.775333333 0.220921555 sp|Q9H6X2|ANTR1_HUMAN 100 0 gi|62870689|gb|AAY18343.1| anthrax toxin receptor/neuroblastoma fusion protein transcript variant 3 [Homo sapiens] 100 0 sp|Q9H6X2|ANTR1_HUMAN Anthrax toxin receptor 1 OS=Homo sapiens GN=ANTXR1 PE=1 SV=2 100 0 Q508I6 Q508I6_HUMAN Anthrax toxin receptor/neuroblastoma fusion protein transcript variant 3 OS=Homo sapiens GN=ANTXR1/NNG1 fusion PE=2 SV=1 - - - - - - - K06238|1|2e-08|61.6|gga:428448|collagen, type VI, alpha!K06594|2|1e-07|58.9|cfa:489930|integrin alpha D GO:0034446//substrate adhesion-dependent cell spreading;GO:0022414//reproductive process;GO:0031532//actin cytoskeleton reorganization GO:0046872//metal ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0005518//collagen binding;GO:0051015//actin filament binding GO:0031258//lamellipodium membrane;GO:0016021//integral to membrane;GO:0031527//filopodium membrane 579 sp|Q8IUX7|AEBP1_HUMAN Adipocyte enhancer-binding protein 1 OS=Homo sapiens GN=AEBP1 PE=1 SV=1 152883 MAAVRGAPLLSCLLALLALCPGGRPQTVLTDDEIEEFLEGFLSELEPEPREDDVEAPPPPEPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLEWPLPPPPSPGPEELPQEGGAPLSNNWQNPGEETHVEAREHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQPRPPPSRRRRPERVWPEPPEEKAPAPAPEERIEPPVKPLLPPLPPDYGDGYVIPNYDDMDYYFGPPPPQKPDAERQTDEEKEELKKPKKEDSSPKEETDKWAVEKGKDHKEPRKGEELEEEWTPTEKVKCPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSVAPVYSYYAQNEVVATDDLDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDEVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGATQCNFILARSNWKRIREIMAMNGNRPIPHIDPSRPMTPQQRRLQQRRLQHRLRLRAQMRLRRLNATTTLGPHTVPPTLPPAPATTLSTTIEPWGLIPPTTAGWEESETETYTEVVTEFGTEVEPEFGTKVEPEFETQLEPEFETQLEPEFEEEEEEEKEEEIATGQAFPFTTVETYTVNFGDF 878 13.4 - 64 60 13 12 3.015 3.215 3.374 24 25 25 * * * 3.201333333 0.179889781 sp|Q8IUX7|AEBP1_HUMAN 100 0 gi|53692189|ref|NP_001120.3| adipocyte enhancer-binding protein 1 precursor [Homo sapiens] >gi|74728002|sp|Q8IUX7.1|AEBP1_HUMAN RecName: Full=Adipocyte enhancer-binding protein 1; Short=AE-binding protein 1; AltName: Full=Aortic carboxypeptidase-like protein; Flags: Precursor >gi|24047247|gb|AAH38588.1| AE binding protein 1 [Homo sapiens] >gi|51094512|gb|EAL23768.1| AE binding protein 1 [Homo sapiens] >gi|119581523|gb|EAW61119.1| AE binding protein 1 [Homo sapiens] 100 0 sp|Q8IUX7|AEBP1_HUMAN Adipocyte enhancer-binding protein 1 OS=Homo sapiens GN=AEBP1 PE=1 SV=1 100 0 B4DJB3 B4DJB3_HUMAN cDNA FLJ55979, highly similar to Homo sapiens AE binding protein 1 (AEBP1), mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K08639|1|0.0|772|mdo:100025097|carboxypeptidase X2 GO:0006355//regulation of transcription, DNA-dependent;GO:0007517//muscle organ development;GO:0001501//skeletal system development;GO:0006508//proteolysis;GO:0007155//cell adhesion GO:0004181//metallocarboxypeptidase activity;GO:0005516//calmodulin binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0003700//sequence-specific DNA binding transcription factor activity GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0005634//nucleus 580 tr|B2R5U1|B2R5U1_HUMAN cDNA, FLJ92620, highly similar to Homo sapiens staphylococcal nuclease domain containing 1 (SND1),mRNA OS=Homo sapiens PE=2 SV=1 117937 MVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKLNSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR 128 7.2 3 7 7 5 5 1.096 0.584 0.599 3 3 2 - - - 0.759666667 0.291369754 tr|B2R5U1|B2R5U1_HUMAN 100 2.00E-51 gi|159164328|pdb|2E6N|A Chain A, Solution Structure Of The Tudor Domain Of Staphylococcal Nuclease Domain-Containing Protein 1 100 0 sp|Q7KZF4|SND1_HUMAN Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens GN=SND1 PE=1 SV=1 100 0 E7ESM6 E7ESM6_HUMAN Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens GN=SND1 PE=4 SV=2 SPCC645.08c 350 6.00E-96 COG1525 Micrococcal nuclease (thermonuclease) homologs L Replication, recombination and repair ; K15979|1|0.0|1762|hsa:27044|staphylococcal nuclease domain-containing protein 1 GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006355//regulation of transcription, DNA-dependent;GO:0031047//gene silencing by RNA;GO:0019048//virus-host interaction GO:0003712//transcription cofactor activity;GO:0003676//nucleic acid binding;GO:0004518//nuclease activity GO:0005739//mitochondrion;GO:0016442//RNA-induced silencing complex;GO:0042470//melanosome;GO:0005634//nucleus 581 tr|B2R5H5|B2R5H5_HUMAN cDNA, FLJ92476, highly similar to Homo sapiens LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM3), mRNA OS=Homo sapiens PE=2 SV=1 13039 MADDVDQQQTTNTVEEPLDPIRLSLDERIYVKMRNDRELRGRLHAYDQHLNMILGDVEETVTTIEIDEETYEEIYKSTKRNIPMLFVRGDGVVLVAPPLRVG 61 11.8 1 2 2 1 1 1.18 1.696 --- 2 2 - - - - 1.438 0.364867099 tr|B2R5H5|B2R5H5_HUMAN 100 5.00E-20 gi|444705548|gb|ELW46970.1| U6 snRNA-associated Sm-like protein LSm3 [Tupaia chinensis] 99.02 8.00E-39 sp|P62310|LSM3_HUMAN U6 snRNA-associated Sm-like protein LSm3 OS=Homo sapiens GN=LSM3 PE=1 SV=2 100 3.00E-38 B2R5H5 B2R5H5_HUMAN cDNA, FLJ92476, highly similar to Homo sapiens LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM3), mRNA OS=Homo sapiens PE=4 SV=1 MTH649 55.5 2.00E-08 COG1958 Small nuclear ribonucleoprotein (snRNP) homolog K Transcription ; K12622|1|7e-39|158|ecb:100629288|U6 snRNA-associated Sm-like protein LSm3 GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0000398//mRNA splicing, via spliceosome GO:0005515//protein binding;GO:0030629//U6 snRNA 3'-end binding GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0005829//cytosol;GO:0071013//catalytic step 2 spliceosome 582 tr|G3V1A4|G3V1A4_HUMAN Cofilin 1 (Non-muscle), isoform CRA_a OS=Homo sapiens GN=CFL1 PE=1 SV=1 24634 MKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL 822 50.3 2 43 24 9 6 0.392 0.307 0.349 15 15 15 * * * 0.349333333 0.04250098 tr|G3V1A4|G3V1A4_HUMAN 100 6.00E-81 gi|403293515|ref|XP_003937759.1| PREDICTED: EGF-containing fibulin-like extracellular matrix protein 2 [Saimiri boliviensis boliviensis] 100 1.00E-81 sp|P23528|COF1_HUMAN Cofilin-1 OS=Homo sapiens GN=CFL1 PE=1 SV=3 100 3.00E-80 H2Q279 H2Q279_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000172757 PE=4 SV=1 - - - - - - - K05765|1|1e-81|301|ecb:100057603|cofilin GO:0007411//axon guidance;GO:0009615//response to virus;GO:0007266//Rho protein signal transduction;GO:0022604//regulation of cell morphogenesis;GO:0001842//neural fold formation;GO:0030168//platelet activation;GO:0001755//neural crest cell migration;GO:0030836//positive regulation of actin filament depolymerization;GO:0006468//protein phosphorylation;GO:0045792//negative regulation of cell size;GO:0043200//response to amino acid stimulus;GO:0002576//platelet degranulation;GO:0030010//establishment of cell polarity;GO:0006606//protein import into nucleus;GO:0000910//cytokinesis GO:0003779//actin binding GO:0032587//ruffle membrane;GO:0016363//nuclear matrix;GO:0031258//lamellipodium membrane;GO:0030864//cortical actin cytoskeleton 583 tr|A8K3Q7|A8K3Q7_HUMAN Annexin OS=Homo sapiens PE=2 SV=1 92263 MAKPAQGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAQEDAQVAAEILEIADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFLKALLALCGGED 62 11.7 1 11 11 7 7 0.461 120.383 0.011 2 2 2 * - - 40.285 69.3672677 tr|A8K3Q7|A8K3Q7_HUMAN 100 0 gi|158254780|dbj|BAF83361.1| unnamed protein product [Homo sapiens] 99.85 0 sp|P08133|ANXA6_HUMAN Annexin A6 OS=Homo sapiens GN=ANXA6 PE=1 SV=3 100 0 A8K3Q7 A8K3Q7_HUMAN Annexin OS=Homo sapiens PE=2 SV=1 - - - - - - - - GO:0006816//calcium ion transport;GO:0006937//regulation of muscle contraction GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding GO:0016324//apical plasma membrane;GO:0043234//protein complex;GO:0042470//melanosome;GO:0048471//perinuclear region of cytoplasm 584 tr|Q5VU21|Q5VU21_HUMAN PAI-1 mRNA-binding protein variant OS=Homo sapiens PE=2 SV=1 52801 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQTNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA 99 8 2 3 3 2 2 0.413 0.587 1.141 3 3 3 * - - 0.713666667 0.380170137 tr|Q5VU21|Q5VU21_HUMAN 100 4.00E-11 gi|71896825|ref|NP_001026464.1| plasminogen activator inhibitor 1 RNA-binding protein [Gallus gallus] 94.85 8.00E-116 sp|Q8NC51|PAIRB_HUMAN Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens GN=SERBP1 PE=1 SV=2 100 5.00E-119 Q5VU21 Q5VU21_HUMAN PAI-1 mRNA-binding protein variant OS=Homo sapiens GN=SERBP1 PE=2 SV=1 - - - - - - - K13199|1|1e-117|423|ssc:100518613|plasminogen activator inhibitor 1 RNA-binding protein - GO:0003730//mRNA 3'-UTR binding;GO:0005515//protein binding GO:0005737//cytoplasm 585 tr|A0A024R4H5|A0A024R4H5_HUMAN DNAation factor, 45kDa, alpha polypeptide, isoform CRA_b OS=Homo sapiens GN=DFFA PE=4 SV=1 33994 MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSSQDLEVGGNQGH 45 9.7 2 2 2 2 2 --- 1.071 --- 1 2 1 - - - 1.071 - tr|A0A024R4H5|A0A024R4H5_HUMAN 100 1.00E-136 gi|47132600|ref|NP_998731.1| DNA fragmentation factor subunit alpha isoform 2 [Homo sapiens] >gi|4926918|gb|AAD32953.1|AF087573_1 DNA fragmentation factor DFF35 [Homo sapiens] >gi|119592062|gb|EAW71656.1| DNA fragmentation factor, 45kDa, alpha polypeptide, isoform CRA_b [Homo sapiens] >gi|119592064|gb|EAW71658.1| DNA fragmentation factor, 45kDa, alpha polypeptide, isoform CRA_b [Homo sapiens] 99.62 4.00E-133 sp|O00273|DFFA_HUMAN DNA fragmentation factor subunit alpha OS=Homo sapiens GN=DFFA PE=1 SV=1 99.62 1.00E-131 Q5T6G6 Q5T6G6_HUMAN DNAation factor, 45kDa, alpha polypeptide OS=Homo sapiens GN=DFFA PE=2 SV=1 - - - - - - - K02310|1|2e-134|478|pon:100173283|DNA fragmentation factor, 45 kD, alpha subunit GO:0035556//intracellular signal transduction;GO:0006309//apoptotic DNA fragmentation;GO:0006917//induction of apoptosis;GO:0043066//negative regulation of apoptotic process GO:0004536//deoxyribonuclease activity GO:0005829//cytosol;GO:0000790//nuclear chromatin;GO:0005654//nucleoplasm 586 tr|B3KY04|B3KY04_HUMAN cDNA FLJ46506 fis, clone THYMU3030752, highly similar to BTB/POZ domain-containing protein KCTD12 OS=Homo sapiens PE=2 SV=1 38732 MALADSTRGLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGSQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQQPGPGPPPSRRGVHKEGSLGDELLPLGYSEPEQQEGASAGAPSPTLELASRSPSGGAAGPLLTPSQSLDGSRRSGYITIGYRGSYTIGRDAQADAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDRPPERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTGTCAFASSTDQSEDKIWTSYTEYVFCRE 70 7.7 1 3 3 2 2 1.532 1.071 1.382 2 2 2 - - - 1.328333333 0.235138966 tr|B3KY04|B3KY04_HUMAN 100 6.00E-82 gi|426375707|ref|XP_004054665.1| PREDICTED: BTB/POZ domain-containing protein KCTD12 [Gorilla gorilla gorilla] 99.69 2.00E-161 sp|Q96CX2|KCD12_HUMAN BTB/POZ domain-containing protein KCTD12 OS=Homo sapiens GN=KCTD12 PE=1 SV=1 100 2.00E-160 B3KY04 B3KY04_HUMAN cDNA FLJ46506 fis, clone THYMU3030752, highly similar to BTB/POZ domain-containing protein KCTD12 OS=Homo sapiens PE=2 SV=1 - - - - - - - - GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0051260//protein homooligomerization GO:0005515//protein binding GO:0045211//postsynaptic membrane;GO:0042734//presynaptic membrane;GO:0030054//cell junction;GO:0043235//receptor complex;GO:0005886//plasma membrane 587 tr|G3V3X5|G3V3X5_HUMAN Latent-transforming growth factor beta-binding protein 2 OS=Homo sapiens GN=LTBP2 PE=4 SV=1 209589 MRPRTKARSPGRALRNPWRGFLPLTLALFVGAGHAQRDPVGRYEPAGGDANRLRRPGGSYPAAAAAKVYSLFREQDAPVAGLQPVERAQPGWGSPRRPTEAEARRPSRAQQSRRVQPPAQTRRSTPLGQQQPAPRTRAAPALPRLGTPQRSGAAPPTPPRGRLTGRNVCGGQCCPGWTTANSTNHCIKPVCEPPCQNRGSCSRPQLCVCRSGFRGARCEEVIPDEEFDPQNSRLAPRRWAERSPNLRRSSAAGEGTLARAQPPAPQSPPAPQSPPAGTLSGLSQTHPSQQHVGLSRTVRLHPTATASSQLSSNALPPGPGLEQRDGTQQAVPLEHPSSPWGLNLTEKIKKIKIVFTPTICKQTCARGHCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPIPQPDREPPGRGSRPRALLEAPLKQSTFTLPLSNQLASVNPSLVKVHIHHPPEASVQIHQVAQVRGGVEEALVENSVETRPPPWLPASPGHSLWDSNNIPARSGEPPRPLPPAAPRPRGLLGRCYLNTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPAGHGYTYASSDIRLSMRKAEEEELARPPREQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDLACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPDDLHYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYVASHPEPPAGFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHCTAKE 1122 8.6 4 50 50 10 10 1.441 1.872 1.54 25 27 27 * * * 1.617666667 0.225752815 tr|G3V3X5|G3V3X5_HUMAN 100 0 gi|9309503|gb|AAF87081.1|AC013451_1 LTBP-2 [Homo sapiens] 97.58 0 sp|Q14767|LTBP2_HUMAN Latent-transforming growth factor beta-binding protein 2 OS=Homo sapiens GN=LTBP2 PE=1 SV=3 100 0 G3V3X5 G3V3X5_HUMAN Latent-transforming growth factor beta-binding protein 2 OS=Homo sapiens GN=LTBP2 PE=4 SV=1 - - - - - - - K08023|1|0.0|3321|hsa:4053|latent transforming growth factor beta binding protein GO:0006605//protein targeting;GO:0009306//protein secretion;GO:0007179//transforming growth factor beta receptor signaling pathway GO:0008201//heparin binding;GO:0005509//calcium ion binding;GO:0019838//growth factor binding GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 588 sp|Q99574|NEUS_HUMAN Neuroserpin OS=Homo sapiens GN=SERPINI1 PE=1 SV=1 53394 MAFLGLFSLLVLQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHPETMNTSGHDFEEL 130 11 - 7 7 4 4 1.152 1.445 1.821 5 5 4 - * * 1.472666667 0.335357024 sp|Q99574|NEUS_HUMAN 100 0 gi|238537787|pdb|3F5N|A Chain A, Structure Of Native Human Neuroserpin >gi|238537788|pdb|3F5N|B Chain B, Structure Of Native Human Neuroserpin >gi|238537789|pdb|3F5N|C Chain C, Structure Of Native Human Neuroserpin >gi|238537790|pdb|3F5N|D Chain D, Structure Of Native Human Neuroserpin >gi|238537791|pdb|3F5N|E Chain E, Structure Of Native Human Neuroserpin 100 0 sp|Q99574|NEUS_HUMAN Neuroserpin OS=Homo sapiens GN=SERPINI1 PE=1 SV=1 100 2.00E-86 C9J6F7 C9J6F7_HUMAN Neuroserpin OS=Homo sapiens GN=SERPINI1 PE=3 SV=1 all0778 201 2.00E-51 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K13963|1|6e-64|245|bfo:BRAFLDRAFT_130749|serpin B!K03982|3|1e-61|237|ssc:396945|plasminogen activator inhibitor-1 GO:0010951//negative regulation of endopeptidase activity;GO:0007417//central nervous system development;GO:0030155//regulation of cell adhesion;GO:0030162//regulation of proteolysis;GO:0007422//peripheral nervous system development GO:0004867//serine-type endopeptidase inhibitor activity GO:0005576//extracellular region 589 tr|F5GWI4|F5GWI4_HUMAN Adenosine deaminase OS=Homo sapiens GN=ADA PE=1 SV=1 45550 MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPDFLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAIDLAGDETIPGSSLLPGHVQAYQAVDILKTERLGHGYHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIFKSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL 44 5 2 7 7 2 2 0.552 0.903 0.62 3 2 3 - * - 0.691666667 0.186151372 tr|F5GWI4|F5GWI4_HUMAN 99.36 2.00E-85 gi|119596311|gb|EAW75905.1| adenosine deaminase, isoform CRA_b [Homo sapiens] 93.39 0 sp|P00813|ADA_HUMAN Adenosine deaminase OS=Homo sapiens GN=ADA PE=1 SV=3 100 5.00E-35 F5GYD4 F5GYD4_HUMAN Adenosine deaminase OS=Homo sapiens GN=ADA PE=4 SV=1 STM1463 141 1.00E-33 COG1816 Adenosine deaminase F Nucleotide transport and metabolism ; K01488|1|0.0|698|hsa:100|adenosine deaminase [EC:3.5.4.4] GO:0060169//negative regulation of adenosine receptor signaling pathway;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0006154//adenosine catabolic process;GO:0046061//dATP catabolic process;GO:0070256//negative regulation of mucus secretion;GO:0002636//positive regulation of germinal center formation;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0033632//regulation of cell-cell adhesion mediated by integrin;GO:0001821//histamine secretion;GO:0048541//Peyer's patch development;GO:0042542//response to hydrogen peroxide;GO:0001829//trophectodermal cell differentiation;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0002314//germinal center B cell differentiation;GO:0046103//inosine biosynthetic process;GO:0043103//hypoxanthine salvage;GO:0001889//liver development;GO:0046111//xanthine biosynthetic process;GO:0002686//negative regulation of leukocyte migration;GO:0048566//embryonic digestive tract development;GO:0001666//response to hypoxia;GO:0050850//positive regulation of calcium-mediated signaling;GO:0010460//positive regulation of heart rate;GO:0030890//positive regulation of B cell proliferation;GO:0007568//aging;GO:0060407//negative regulation of penile erection;GO:0001890//placenta development;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0045987//positive regulation of smooth muscle contraction;GO:0032261//purine nucleotide salvage;GO:0043278//response to morphine;GO:0042323//negative regulation of circadian sleep/wake cycle, non-REM sleep;GO:0048286//lung alveolus development;GO:0006157//deoxyadenosine catabolic process GO:0004000//adenosine deaminase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0001883//purine nucleoside binding GO:0005764//lysosome;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0032839//dendrite cytoplasm;GO:0030054//cell junction;GO:0009897//external side of plasma membrane;GO:0043025//neuronal cell body;GO:0060205//cytoplasmic membrane-bounded vesicle lumen 590 tr|H0YB13|H0YB13_HUMAN Stanniocalcin-2 (Fragment) OS=Homo sapiens GN=STC2 PE=4 SV=1 17185 XQNTAEIQHCLVNAGDVGCGVFECFENNSCEIRGLHGICMTFLHNAGKFDAQGKSFIKDALKCKAHALRHRFGCISRKCPAIREMVSQLQRECYLKHDLCAAAQENTRVIVEMIHFKDLLLHE 455 7.3 2 33 33 1 1 0.647 0.783 1.059 19 19 19 - * - 0.829666667 0.209926971 tr|H0YB13|H0YB13_HUMAN 100 1.00E-67 gi|114603422|ref|XP_518105.2| PREDICTED: stanniocalcin-2 isoform 2 [Pan troglodytes] 100 1.00E-68 sp|O76061|STC2_HUMAN Stanniocalcin-2 OS=Homo sapiens GN=STC2 PE=1 SV=1 100 3.00E-67 B3KNF2 B3KNF2_HUMAN cDNA FLJ14484 fis, clone MAMMA1002485, highly similar to Stanniocalcin-2 OS=Homo sapiens PE=2 SV=1 - - - - - - - - GO:0046697//decidualization;GO:0007166//cell surface receptor signaling pathway;GO:0071456//cellular response to hypoxia;GO:0043434//response to peptide hormone stimulus;GO:0033280//response to vitamin D;GO:0007267//cell-cell signaling;GO:0007566//embryo implantation GO:0005179//hormone activity GO:0005576//extracellular region 591 tr|A0A024R7F1|A0A024R7F1_HUMAN Protein kinase C substrate 80K-H, isoform CRA_a OS=Homo sapiens GN=PRKCSH PE=4 SV=1 70571 MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTTNEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTTVRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL 243 9.7 3 11 11 4 4 1.023 1.012 0.948 7 7 7 - - - 0.994333333 0.040501029 tr|A0A024R7F1|A0A024R7F1_HUMAN 100 2.00E-89 gi|15929445|gb|AAH15154.1| Unknown (protein for IMAGE:3883364), partial [Homo sapiens] 98.65 0 sp|P14314|GLU2B_HUMAN Glucosidase 2 subunit beta OS=Homo sapiens GN=PRKCSH PE=1 SV=2 98.84 1.00E-63 A2VCQ4 A2VCQ4_HUMAN PRKCSH protein (Fragment) OS=Homo sapiens GN=PRKCSH PE=2 SV=1 - - - - - - - K08288|1|0.0|818|hsa:5589|protein kinase C substrate 80K-H GO:0007243//intracellular protein kinase cascade;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006457//protein folding;GO:0045087//innate immune response;GO:0043687//post-translational protein modification GO:0005080//protein kinase C binding;GO:0003824//catalytic activity GO:0005788//endoplasmic reticulum lumen 592 sp|P22314|UBA1_HUMAN Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens GN=UBA1 PE=1 SV=3 >tr|A0A024R1A3|A0A024R1A3_HUMAN Ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing), isoform CRA_a OS=Homo sapiens GN=UBE1 PE=3 SV=1 135285 MSSSPLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALECLPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTGSQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQELQSANASVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR 227 6.3 - 8 8 5 5 0.725 0.538 0.524 4 5 3 - * - 0.595666667 0.112224477 sp|P22314|UBA1_HUMAN 100 0 gi|24485|emb|CAA37078.1| unnamed protein product [Homo sapiens] 100 0 sp|P22314|UBA1_HUMAN Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens GN=UBA1 PE=1 SV=3 100 0 B4DDE4 B4DDE4_HUMAN Uncharacterized protein OS=Homo sapiens GN=UBA1 PE=2 SV=1 YKL210w 1094 0 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 H Coenzyme transport and metabolism ; K03178|1|0.0|2140|hsa:7317|ubiquitin-activating enzyme E1 [EC:6.3.2.19] GO:0016567//protein ubiquitination;GO:0008219//cell death GO:0016874//ligase activity;GO:0008641//small protein activating enzyme activity;GO:0005515//protein binding;GO:0005524//ATP binding - 593 sp|P43490|NAMPT_HUMAN Nicotinamide phosphoribosyltransferase OS=Homo sapiens GN=NAMPT PE=1 SV=1 >tr|A0A024R718|A0A024R718_HUMAN Pre-B-cell colony enhancing factor 1, isoform CRA_a OS=Homo sapiens GN=PBEF1 PE=4 SV=1 70374 MNPAAEAEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKLRKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEAAHH 48 8.4 - 3 3 3 3 1.29 1.549 1.239 2 2 2 - - - 1.359333333 0.166223745 sp|P43490|NAMPT_HUMAN 100 0 gi|256032335|pdb|3DGR|A Chain A, Crystal Structure Of Human Nampt Complexed With Adp Analogue >gi|256032336|pdb|3DGR|B Chain B, Crystal Structure Of Human Nampt Complexed With Adp Analogue >gi|256032337|pdb|3DHD|A Chain A, Crystal Structure Of Human Nampt Complexed With Nicotinamide Mononucleotide And Pyrophosphate >gi|256032338|pdb|3DHD|B Chain B, Crystal Structure Of Human Nampt Complexed With Nicotinamide Mononucleotide And Pyrophosphate >gi|256032339|pdb|3DHF|A Chain A, Crystal Structure Of Phosphorylated Mimic Form Of Human Nampt Complexed With Nicotinamide Mononucleotide And Pyrophosphate >gi|256032340|pdb|3DHF|B Chain B, Crystal Structure Of Phosphorylated Mimic Form Of Human Nampt Complexed With Nicotinamide Mononucleotide And Pyrophosphate >gi|256032341|pdb|3DKJ|A Chain A, Crystal Structure Of Human Nampt Complexed With Benzamide And Phosphoribosyl Pyrophosphate >gi|256032342|pdb|3DKJ|B Chain B, Crystal Structure Of Human Nampt Complexed With Benzamide And Phosphoribosyl Pyrophosphate >gi|256032343|pdb|3DKL|A Chain A, Crystal Structure Of Phosphorylated Mimic Form Of Human Nampt Complexed With Benzamide And Phosphoribosyl Pyrophosphate >gi|256032344|pdb|3DKL|B Chain B, Crystal Structure Of Phosphorylated Mimic Form Of Human Nampt Complexed With Benzamide And Phosphoribosyl Pyrophosphate 100 0 sp|P43490|NAMPT_HUMAN Nicotinamide phosphoribosyltransferase OS=Homo sapiens GN=NAMPT PE=1 SV=1 100 0 G3R936 G3R936_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=ENSG00000105835 PE=4 SV=1 RSp0836 405 6.00E-113 COG1488 Nicotinic acid phosphoribosyltransferase H Coenzyme transport and metabolism ; K03462|1|0.0|986|hsa:10135|nicotinamide phosphoribosyltransferase [EC:2.4.2.12] GO:0008286//insulin receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007049//cell cycle;GO:0009435//NAD biosynthetic process;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0006769//nicotinamide metabolic process;GO:0007565//female pregnancy;GO:0014070//response to organic cyclic compound;GO:0060612//adipose tissue development;GO:0006767//water-soluble vitamin metabolic process;GO:0048661//positive regulation of smooth muscle cell proliferation GO:0008144//drug binding;GO:0047280//nicotinamide phosphoribosyltransferase activity;GO:0004514//nicotinate-nucleotide diphosphorylase (carboxylating) activity;GO:0005125//cytokine activity;GO:0004516//nicotinate phosphoribosyltransferase activity;GO:0042803//protein homodimerization activity GO:0005829//cytosol;GO:0005634//nucleus 594 tr|Q53FP8|Q53FP8_HUMAN Calponin (Fragment) OS=Homo sapiens PE=2 SV=1 40637 MSSAHFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGNNFMDGLKDGIILCEFINKLQPGSVKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKTKGNKVNVGVKYAEKQERKFEPGKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQATISQQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTPEYPELGEPAHNHHAHNYYNSA 156 7.4 1 6 6 2 2 0.496 0.576 0.421 4 4 4 * - * 0.497666667 0.07751344 tr|Q53FP8|Q53FP8_HUMAN 100 7.00E-162 gi|62898029|dbj|BAD96954.1| calponin 1, basic, smooth muscle variant [Homo sapiens] 99.65 6.00E-162 sp|P51911|CNN1_HUMAN Calponin-1 OS=Homo sapiens GN=CNN1 PE=1 SV=2 100 3.00E-161 Q53FP8 Q53FP8_HUMAN Calponin 1, basic, smooth muscle variant (Fragment) OS=Homo sapiens PE=2 SV=1 ECU03g1150 71.2 2.00E-12 COG5199 Calponin Z Cytoskeleton ; K06084|1|2e-13|77.0|bfo:BRAFLDRAFT_117217|F-box protein 20 GO:0006940//regulation of smooth muscle contraction;GO:0031032//actomyosin structure organization GO:0003779//actin binding;GO:0005516//calmodulin binding GO:0005856//cytoskeleton 595 tr|B3KME2|B3KME2_HUMAN cDNA FLJ10772 fis, clone NT2RP4000243, highly similar to Cartilage-associated protein OS=Homo sapiens PE=2 SV=1 53794 MEPGRRGAAALLALLCVACALRAGRAQYERYSFRSFPRDELMPLESAYRHALGKYSGEHWAESVGYLEISLRLHRLLRDSEAFCHRNCSAAPQPEPAAGLASYPELRLFGGLLRRAHCLKRCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPKAIAAAHTFLLKHPDDEMMKRNMAYYKSLPGAEDYIKDLETKSYESLFIRAVRAYNGENWRTSITDMELALPDFFKAFYECLAACEGSREIKDFKDFYLSIADHYVEVLECKIQCEENLTPVIGGYPVEKFVATMYHYLQFAYYKLNDLKNAAPCAVSYLLFDQNDKVMQQNLVYYQYHRDTWGLSDEHFQPRPEAVQFFNVTTLQKELYDFAKENIMDDDEGEVVEYVDDLLELEETS 56 6.2 5 4 2 3 2 1.488 1.515 1.668 2 2 2 - - - 1.557 0.097072138 tr|B3KME2|B3KME2_HUMAN 100 5.00E-131 gi|397138233|ref|XP_003403813.2| PREDICTED: cartilage-associated protein-like [Homo sapiens] 99.72 0 sp|O75718|CRTAP_HUMAN Cartilage-associated protein OS=Homo sapiens GN=CRTAP PE=1 SV=1 100 0 B3KME2 B3KME2_HUMAN cDNA FLJ10772 fis, clone NT2RP4000243, highly similar to Cartilage-associated protein OS=Homo sapiens PE=2 SV=1 - - - - - - - K08134|1|8e-51|201|ptr:456811|leucine proline-enriched proteoglycan (leprecan) GO:0007283//spermatogenesis;GO:0030198//extracellular matrix organization - GO:0005788//endoplasmic reticulum lumen;GO:0005578//proteinaceous extracellular matrix 596 sp|A6NDG6|PGP_HUMAN Phosphoglycolate phosphatase OS=Homo sapiens GN=PGP PE=1 SV=1 38395 MAAAEAGGDDARCVRLSAERAQALLADVDTLLFDCDGVLWRGETAVPGAPEALRALRARGKRLGFITNNSSKTRAAYAEKLRRLGFGGPAGPGASLEVFGTAYCTALYLRQRLAGAPAPKAYVLGSPALAAELEAVGVASVGVGPEPLQGEGPGDWLHAPLEPDVRAVVVGFDPHFSYMKLTKALRYLQQPGCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPERTVMVGDRLDTDILLGATCGLKTILTLTGVSTLGDVKNNQESDCVSKKKMVPDFYVDSIADLLPALQG 60 9 - 5 5 2 2 0.928 1.297 0.875 2 3 3 - - - 1.033333333 0.229874603 sp|A6NDG6|PGP_HUMAN 100 3.00E-148 gi|108796653|ref|NP_001035830.1| phosphoglycolate phosphatase [Homo sapiens] >gi|166987826|sp|A6NDG6.1|PGP_HUMAN RecName: Full=Phosphoglycolate phosphatase; Short=PGP; Short=PGPase >gi|119605940|gb|EAW85534.1| hCG41030 [Homo sapiens] 100 3.00E-149 sp|A6NDG6|PGP_HUMAN Phosphoglycolate phosphatase OS=Homo sapiens GN=PGP PE=1 SV=1 99.42 2.00E-95 G3S149 G3S149_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=PGP PE=4 SV=1 SPBC15D4.15 178 1.00E-44 COG0647 Predicted sugar phosphatases of the HAD superfamily G Carbohydrate transport and metabolism ; K01091|1|2e-150|531|ssc:100739035|phosphoglycolate phosphatase [EC:3.1.3.18] GO:0060548//negative regulation of cell death;GO:0006855//drug transmembrane transport;GO:0005975//carbohydrate metabolic process;GO:0072089//stem cell proliferation;GO:0006200//ATP catabolic process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0042908//xenobiotic transport GO:0008559//xenobiotic-transporting ATPase activity;GO:0008967//phosphoglycolate phosphatase activity;GO:0005524//ATP binding GO:0000139//Golgi membrane;GO:0016021//integral to membrane;GO:0009986//cell surface;GO:0046581//intercellular canaliculus;GO:0016324//apical plasma membrane 597 tr|Q5JXI8|Q5JXI8_HUMAN Four and a half LIM domains protein 1 (Fragment) OS=Homo sapiens GN=FHL1 PE=1 SV=1 41308 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSV 205 23 5 9 9 5 5 0.93 1.146 1.125 7 7 7 - - - 1.067 0.119109194 tr|Q5JXI8|Q5JXI8_HUMAN 100 1.00E-147 gi|207080154|ref|NP_001128823.1| DKFZP468L0125 protein precursor [Pongo abelii] >gi|228480209|ref|NP_001153173.1| four and a half LIM domains protein 1 isoform 3 precursor [Homo sapiens] 100 5.00E-133 sp|Q13642|FHL1_HUMAN Four and a half LIM domains protein 1 OS=Homo sapiens GN=FHL1 PE=1 SV=4 100 8.00E-115 Q5JXH7 Q5JXH7_HUMAN Four and a half LIM domains 1 (Fragment) OS=Homo sapiens GN=FHL1 PE=2 SV=1 - - - - - - - K14365|1|2e-148|525|pon:100189735|four and a half LIM domains protein 1 GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0030308//negative regulation of cell growth;GO:0007517//muscle organ development;GO:0009887//organ morphogenesis;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0030154//cell differentiation GO:0008270//zinc ion binding;GO:0005515//protein binding GO:0005829//cytosol;GO:0005634//nucleus;GO:0005886//plasma membrane 598 tr|Q6FIE5|Q6FIE5_HUMAN PHP14 protein OS=Homo sapiens GN=PHP14 PE=2 SV=1 17301 MAVADLALIPDVDADSDGVFKYVLIRIHSAPRSGAPAAESKEIVRGYKWAEYHADIYDKVSGDMQKQGCDCECLGGGRTSHQSQDKKIHVYGYSMAYGPAQHAISTEKIKAKYPDYEVTWANDGY 87 8.8 1 3 3 1 1 1.111 0.987 0.899 3 3 3 - - - 0.999 0.106508216 tr|Q6FIE5|Q6FIE5_HUMAN 100 7.00E-68 gi|49065388|emb|CAG38512.1| PHP14 [Homo sapiens] 97.6 3.00E-67 sp|Q9NRX4|PHP14_HUMAN 14 kDa phosphohistidine phosphatase OS=Homo sapiens GN=PHPT1 PE=1 SV=1 100 3.00E-67 Q6FIE5 Q6FIE5_HUMAN PHP14 protein OS=Homo sapiens GN=PHP14 PE=2 SV=1 - - - - - - - K01112|1|2e-56|217|cfa:491245|[EC:3.1.3.-] GO:0035971//peptidyl-histidine dephosphorylation;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0051350//negative regulation of lyase activity;GO:2000147//positive regulation of cell motility;GO:2000984//negative regulation of ATP citrate synthase activity;GO:2000249//regulation of actin cytoskeleton reorganization GO:0008969//phosphohistidine phosphatase activity;GO:0019855//calcium channel inhibitor activity;GO:0044325//ion channel binding;GO:0004721//phosphoprotein phosphatase activity GO:0005829//cytosol 599 tr|A4D198|A4D198_HUMAN Similar to mKIAA0038 protein OS=Homo sapiens GN=LOC392647 PE=4 SV=1 37870 MYSFSCSLIWLSSPPHEERSIDIYYLPKNRLEAISNLTSGLESSRGQLPFALLKNKKGFLSERRRQMADFDTYDDQAYSSFGSGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVRGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGFRDDFLGGRGGSRPGDRRTGPPMGSRFGDGPPLGGSNMDFREPTEEESAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQK 103 6.8 4 4 4 2 2 0.428 0.729 0.614 3 3 3 - - * 0.590333333 0.151889214 tr|A4D198|A4D198_HUMAN 100 1.00E-83 gi|119614301|gb|EAW93895.1| hCG1745675 [Homo sapiens] 96.05 1.00E-80 sp|Q5RBR8|IF4H_PONAB Eukaryotic translation initiation factor 4H OS=Pongo abelii GN=EIF4H PE=2 SV=1 100 1.00E-123 A4D198 A4D198_HUMAN Similar to mKIAA0038 protein OS=Homo sapiens GN=LOC392647 PE=4 SV=1 SPAC140.02 59.3 8.00E-09 COG0724 RNA-binding proteins (RRM domain) R General function prediction only ; K03258|1|2e-15|83.2|dre:553214|translation initiation factor 4B GO:0019953//sexual reproduction;GO:0048589//developmental growth;GO:0006446//regulation of translational initiation GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding GO:0016281//eukaryotic translation initiation factor 4F complex;GO:0005829//cytosol 600 tr|E9PBG7|E9PBG7_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CAMK2D PE=1 SV=1 70161 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKINNKANVVTSPKENIPTPALEPQTTVIHNPDGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 107 7.6 - 4 4 3 3 0.706 0.39 0.78 3 3 3 * * - 0.625333333 0.207136026 tr|E9PBG7|E9PBG7_HUMAN 100 0 gi|402870282|ref|XP_003899161.1| PREDICTED: calcium/calmodulin-dependent protein kinase type II subunit delta isoform 4 [Papio anubis] 98.24 0 sp|O77708|KCC2D_RABIT Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Oryctolagus cuniculus GN=CAMK2D PE=2 SV=2 100 0 E9Q1V9 E9Q1V9_MOUSE Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Mus musculus GN=Camk2d PE=4 SV=1 SPAC14C4.03 167 5.00E-41 COG0515 Serine/threonine protein kinase RTKL General function prediction only ; Signal transduction mechanisms ; Transcription ; Replication, recombination and repair ; K04515|1|0.0|1073|mcc:702504|calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] GO:0006468//protein phosphorylation GO:0004683//calmodulin-dependent protein kinase activity;GO:0005524//ATP binding;GO:0005516//calmodulin binding - 601 tr|Q59ET0|Q59ET0_HUMAN Glucan , branching enzyme 1 variant (Fragment) OS=Homo sapiens PE=2 SV=1 97162 RAPDRRGSPRLASTRLGALRLRPSRRVPARAPAPAQAPLDPLGPRLLGLRRNMAAPMTPAARPEDYEAALNAALADVPELARLLEIDPYLKPYAVDFQRRYKQFSQILKNIGENEGGIDKFSRGYESFGVHRCADGGLYCKEWAPGAEGVFLTGDFNGWNPFSYPYKKLDYGKWELYIPPKQNKSVLVPHGSKLKVVITSKSGEILYRISPWAKYVVREGDNVNYDWIHWDPEHSYEFKHSRPKKPRSLRIYESHVGISSHEGKVASYKHFTCNVLPRIKGLGYNCIQLMAIMEHAYYASFGYQITSFFAASSRYGTPEELQELVDTAHSMGIIVLLDVVHSHASKNSADGLNMFDGTDSCYFHSGPRGTHDLWDSRLFAYSSWEVLRFLLSNIRWWLEEYRFDGFRFDGVTSMLYHHHGVGQGFSGDYSEYFGLQVDEDALTYLMLANHLVHTLCPDSITIAEDVSGMPALCSPISQGGGGFDYRLAMAIPDKWIQLLKEFKDEDWNMGDIVYTLTNRRYLEKCIAYAESHDQALVGDKSLAFWLMDAEMYTNMSVLTPFTPVIDRGIQLHKMIRLITHGLGGEGYLNFMGNEFGHPEWLDFPRKGNNESYHYARRQFHLTDDDLLRYKFLNNFDRDMNRLEERYGWLAAPQAYVSEKHEGNKIIAFERAGLLFIFNFHPSKSYTDYRVGTALPGKFKIVLDSDAAEYGGHQRLDHSTDFFSEAFEHNGRPYSLLVYIPSRVALILQNVDLPN 320 10.6 1 18 18 7 7 0.867 1.214 0.808 11 11 10 - - * 0.963 0.219364993 tr|Q59ET0|Q59ET0_HUMAN 100 0 gi|62089042|dbj|BAD92968.1| Glucan , branching enzyme 1 variant [Homo sapiens] 99.86 0 sp|Q04446|GLGB_HUMAN 1,4-alpha-glucan-branching enzyme OS=Homo sapiens GN=GBE1 PE=1 SV=3 100 0 Q59ET0 Q59ET0_HUMAN Glucan , branching enzyme 1 variant (Fragment) OS=Homo sapiens PE=2 SV=1 YEL011w 786 0 COG0296 1,4-alpha-glucan branching enzyme G Carbohydrate transport and metabolism ; K00700|1|0.0|1464|hsa:2632|1,4-alpha-glucan branching enzyme [EC:2.4.1.18] GO:0005978//glycogen biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0043169//cation binding;GO:0030246//carbohydrate binding;GO:0003844//1,4-alpha-glucan branching enzyme activity GO:0005829//cytosol 602 tr|B2RDE8|B2RDE8_HUMAN cDNA, FLJ96580, highly similar to Homo sapiens hepatoma-derived growth factor (high-mobility group protein 1-like) (HDGF), mRNA OS=Homo sapiens PE=2 SV=1 35116 MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNERKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTLSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 85 13.8 1 6 6 3 3 1.608 1.594 1.809 3 3 2 - * - 1.670333333 0.120292699 tr|B2RDE8|B2RDE8_HUMAN 100 9.00E-105 gi|189054911|dbj|BAG37895.1| unnamed protein product [Homo sapiens] 99.17 4.00E-104 sp|P51858|HDGF_HUMAN Hepatoma-derived growth factor OS=Homo sapiens GN=HDGF PE=1 SV=1 100 3.00E-104 B2RDE8 B2RDE8_HUMAN cDNA, FLJ96580, highly similar to Homo sapiens hepatoma-derived growth factor (high-mobility group protein 1-like) (HDGF), mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K00020|1|2e-09|62.8|aag:AaeL_AAEL006684|3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] GO:0006355//regulation of transcription, DNA-dependent;GO:0008283//cell proliferation;GO:0006987//activation of signaling protein activity involved in unfolded protein response GO:0008083//growth factor activity;GO:0000166//nucleotide binding;GO:0008201//heparin binding;GO:0003677//DNA binding GO:0005654//nucleoplasm;GO:0005615//extracellular space;GO:0005737//cytoplasm 603 tr|E5RJR5|E5RJR5_HUMAN S-phase kinase-associated protein 1 OS=Homo sapiens GN=SKP1 PE=1 SV=1 24659 MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKYTLRKTTVSLQAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK 117 13.5 3 6 6 3 3 0.991 0.904 0.893 4 4 4 - - - 0.929333333 0.053687367 tr|E5RJR5|E5RJR5_HUMAN 100 4.00E-28 gi|149451884|ref|XP_001513378.1| PREDICTED: S-phase kinase-associated protein 1-like, partial [Ornithorhynchus anatinus] 93.25 1.00E-62 sp|P63208|SKP1_HUMAN S-phase kinase-associated protein 1 OS=Homo sapiens GN=SKP1 PE=1 SV=2 100 3.00E-63 F7H810 F7H810_MACMU Uncharacterized protein OS=Macaca mulatta PE=4 SV=1 SPBC409.05 163 9.00E-41 COG5201 SCF ubiquitin ligase, SKP1 component O Posttranslational modification, protein turnover, chaperones ; K03094|1|9e-63|238|ptr:462063|S-phase kinase-associated protein 1 GO:0000084//S phase of mitotic cell cycle;GO:0035518//histone H2A monoubiquitination;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007219//Notch signaling pathway;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0000080//G1 phase of mitotic cell cycle;GO:0000082//G1/S transition of mitotic cell cycle;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016032//viral reproduction GO:0004842//ubiquitin-protein ligase activity;GO:0005515//protein binding GO:0005829//cytosol;GO:0031519//PcG protein complex;GO:0019005//SCF ubiquitin ligase complex;GO:0005654//nucleoplasm 604 tr|A8K274|A8K274_HUMAN cDNA FLJ78227, highly similar to Homo sapiens pituitary tumor-transforming 1 interacting protein (PTTG1IP), mRNA OS=Homo sapiens PE=2 SV=1 24644 MAPGVARGPTPYWRLRLGGAALLLLLIPVAAAQEPPGAACSQNTNKTCEECLKNVSCLWCNTNKACLDYPVTSVLPPASLCKLSSARWGVCWVNFEALIITMSVVGGTLLLGIAICCCCCCRRKRSRKPDRSEEKAMREREERRIRQEERRAEMKTRHEIRKKYGLFKEENPYARFENN 70 10.1 3 2 2 1 1 0.759 0.782 0.891 2 2 2 - - - 0.810666667 0.070514774 tr|A8K274|A8K274_HUMAN 100 2.00E-65 gi|158261301|dbj|BAF82828.1| unnamed protein product [Homo sapiens] 99.44 7.00E-65 sp|Q5NVI6|PTTG_PONAB Pituitary tumor-transforming gene 1 protein-interacting protein OS=Pongo abelii GN=PTTG1IP PE=2 SV=2 100 6.00E-65 A8K274 A8K274_HUMAN cDNA FLJ78227, highly similar to Homo sapiens pituitary tumor-transforming 1 interacting protein (PTTG1IP), mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - - GO:0006606//protein import into nucleus - GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005634//nucleus 605 tr|B2R6P3|B2R6P3_HUMAN cDNA, FLJ93047, highly similar to Homo sapiens matrix metallopeptidase 14 (membrane-inserted) (MMP14), mRNA OS=Homo sapiens PE=2 SV=1 76188 MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLLQYGYLPPGDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPTPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV 253 8.4 2 18 18 5 5 0.91 1.244 1.121 9 10 10 - * - 1.091666667 0.168921086 tr|B2R6P3|B2R6P3_HUMAN 100 3.00E-99 gi|5821877|pdb|1BQQ|M Chain M, Crystal Structure Of The Mt1-Mmp--Timp-2 Complex >gi|6137627|pdb|1BUV|M Chain M, Crystal Structure Of The Mt1-Mmp-Timp-2 Complex 99.63 0 sp|P50281|MMP14_HUMAN Matrix metalloproteinase-14 OS=Homo sapiens GN=MMP14 PE=1 SV=3 100 0 B2R6P3 B2R6P3_HUMAN cDNA, FLJ93047, highly similar to Homo sapiens matrix metallopeptidase 14 (membrane-inserted) (MMP14), mRNA OS=Homo sapiens PE=2 SV=1 MA4674 57 9.00E-08 COG5549 Predicted Zn-dependent protease O Posttranslational modification, protein turnover, chaperones ; K07763|1|0.0|999|hsa:4323|matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80] GO:0001525//angiogenesis;GO:0010952//positive regulation of peptidase activity;GO:0030307//positive regulation of cell growth;GO:0030324//lung development;GO:0001541//ovarian follicle development;GO:0022617//extracellular matrix disassembly;GO:0031638//zymogen activation;GO:0048771//tissue remodeling;GO:0009612//response to mechanical stimulus;GO:0001935//endothelial cell proliferation;GO:0051895//negative regulation of focal adhesion assembly;GO:0043627//response to estrogen stimulus;GO:0001503//ossification;GO:0014070//response to organic cyclic compound;GO:0001666//response to hypoxia;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006508//proteolysis;GO:0043615//astrocyte cell migration;GO:0030335//positive regulation of cell migration;GO:0006979//response to oxidative stress GO:0005178//integrin binding;GO:0016504//peptidase activator activity;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0004222//metalloendopeptidase activity;GO:0003700//sequence-specific DNA binding transcription factor activity GO:0042470//melanosome;GO:0005796//Golgi lumen;GO:0005887//integral to plasma membrane;GO:0031012//extracellular matrix 606 tr|A0A087WW43|A0A087WW43_HUMAN Inter-alpha-trypsin inhibitor heavy chain H3 OS=Homo sapiens GN=ITIH3 PE=4 SV=1 89310 MAFAWWPCLILALLSSLAASGFPRSPFRLLGKRSLPEGVANGIEVYSTKINSKVTSRFAHNVVTMRAVNRADTAKEVSFDVELPKTAFITNFTLTIDGVTYPGNVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVKHFEIEVDIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTITYDVNRESPGNVQIVNGYFVHFFAPQGLPVVPKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKEHLVQATPENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGFARRIYEDSDADLQLQGFYEEVANPLLTGVEMEYPENAILDLTQNTYQHFYDGSEIVVAGRLVDEDMNSFKADVKGHGATNDLTFTEEVDMKEMEKALQERDYIFGNYIERLWAYLTIEQLLEKRKNAHGEEKENLTARALDLSLKYHFVTPLTSMVVTKPEDNEDERAIADKPGEGGDSHTGEPRHVLPDQLPASSKPLLLCGRGSPLHHPNSGERRCPLLQHR 210 4.6 3 10 10 3 3 0.789 0.625 0.549 5 5 6 - * * 0.654333333 0.12265942 tr|A0A087WW43|A0A087WW43_HUMAN 99.85 0 gi|119585666|gb|EAW65262.1| inter-alpha (globulin) inhibitor H3, isoform CRA_a [Homo sapiens] 98.73 0 sp|Q06033|ITIH3_HUMAN Inter-alpha-trypsin inhibitor heavy chain H3 OS=Homo sapiens GN=ITIH3 PE=1 SV=2 100 0 C9JX84 C9JX84_HUMAN Inter-alpha-trypsin inhibitor heavy chain H3 OS=Homo sapiens GN=ITIH3 PE=4 SV=2 alr4412 102 2.00E-21 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R General function prediction only ; K05316|1|1e-09|65.5|dmo:Dmoj_GI17296|voltage-dependent calcium channel alpha-2/delta, invertebrate GO:0030212//hyaluronan metabolic process;GO:0010951//negative regulation of endopeptidase activity GO:0004867//serine-type endopeptidase inhibitor activity GO:0005576//extracellular region 607 tr|A0A024R580|A0A024R580_HUMAN Calpain 1, (Mu/I) large subunit, isoform CRA_a OS=Homo sapiens GN=CAPN1 PE=4 SV=1 93955 MSEEIITPVYCTGVSAQVQKQRARELGLGRHENAIKYLGQDYEQLRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKSRTIRKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGDRESGCSFVLALMQKHRRRERRFGRDMETIGFAVYESHQLVGQPAVHLKRDFFLANASRARSEQFINLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQANLPDEQVLSEEEIDENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA 184 12.2 2 13 13 7 7 1.518 1.204 0.937 6 7 4 * - - 1.219666667 0.290816666 tr|A0A024R580|A0A024R580_HUMAN 100 0 gi|119594772|gb|EAW74366.1| calpain 1, (mu/I) large subunit, isoform CRA_a [Homo sapiens] >gi|119594777|gb|EAW74371.1| calpain 1, (mu/I) large subunit, isoform CRA_a [Homo sapiens] 99.44 0 sp|P07384|CAN1_HUMAN Calpain-1 catalytic subunit OS=Homo sapiens GN=CAPN1 PE=1 SV=1 99.44 0 G3QXN8 G3QXN8_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=CAPN1 PE=4 SV=1 - - - - - - - K01367|1|0.0|1444|hsa:823|calpain-1 [EC:3.4.22.52] GO:0016540//protein autoprocessing;GO:0008284//positive regulation of cell proliferation;GO:0006508//proteolysis;GO:0032801//receptor catabolic process GO:0008092//cytoskeletal protein binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding GO:0005737//cytoplasm;GO:0005886//plasma membrane 608 sp|P10915|HPLN1_HUMAN Hyaluronan and proteoglycan link protein 1 OS=Homo sapiens GN=HAPLN1 PE=2 SV=2 >tr|A0A024RAK9|A0A024RAK9_HUMAN Hyaluronan and proteoglycan link protein 1, isoform CRA_a OS=Homo sapiens GN=HAPLN1 PE=4 SV=1 47156 MKSLLLLVLISICWADHLSDNYTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN 1573 36.4 - 89 89 10 10 1.104 0.624 0.796 52 51 52 - - * 0.841333333 0.243189912 sp|P10915|HPLN1_HUMAN 100 0 gi|4503053|ref|NP_001875.1| hyaluronan and proteoglycan link protein 1 precursor [Homo sapiens] >gi|130310|sp|P10915.2|HPLN1_HUMAN RecName: Full=Hyaluronan and proteoglycan link protein 1; AltName: Full=Cartilage-linking protein 1; Short=Cartilage-link protein; AltName: Full=Proteoglycan link protein; Flags: Precursor >gi|34378|emb|CAA35462.1| cartilage link protein [Homo sapiens] >gi|1151009|gb|AAA85216.1| link protein [Homo sapiens] >gi|119616318|gb|EAW95912.1| hyaluronan and proteoglycan link protein 1, isoform CRA_a [Homo sapiens] >gi|119616319|gb|EAW95913.1| hyaluronan and proteoglycan link protein 1, isoform CRA_a [Homo sapiens] 100 0 sp|P10915|HPLN1_HUMAN Hyaluronan and proteoglycan link protein 1 OS=Homo sapiens GN=HAPLN1 PE=2 SV=2 100 1.00E-83 D6RC59 D6RC59_HUMAN Hyaluronan and proteoglycan link protein 1 (Fragment) OS=Homo sapiens GN=HAPLN1 PE=4 SV=1 - - - - - - - K06848|1|0.0|737|hsa:1404|hyaluronan and proteoglycan link protein 1 GO:0007155//cell adhesion GO:0005540//hyaluronic acid binding;GO:0005198//structural molecule activity GO:0005578//proteinaceous extracellular matrix 609 tr|Q53GN4|Q53GN4_HUMAN WD repeat domain 1, isoform CRA_a (Fragment) OS=Homo sapiens GN=WDR1 PE=2 SV=1 79295 MPYEIKKVFASLPQVERGVSKIIGGDPKGNNFLYTNGKCVILRNIDNPALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTVGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFAGKGHTNQVSRMTVDESGQLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQIVLLKDQRKCFSIDNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTITY 473 18.6 3 26 26 9 9 0.618 0.509 0.41 18 18 17 - * * 0.512333333 0.104040056 tr|Q53GN4|Q53GN4_HUMAN 100 2.00E-124 gi|50949306|emb|CAB53674.2| hypothetical protein [Homo sapiens] 99.83 0 sp|O75083|WDR1_HUMAN WD repeat-containing protein 1 OS=Homo sapiens GN=WDR1 PE=1 SV=4 100 0 Q53GN4 Q53GN4_HUMAN WD repeat domain 1, isoform CRA_a (Fragment) OS=Homo sapiens GN=WDR1 PE=2 SV=1 MA2525 116 1.00E-25 COG2319 FOG: WD40 repeat R General function prediction only ; K12662|1|7e-17|89.4|api:100163110|U4/U6 small nuclear ribonucleoprotein PRP4!K14963|3|1e-16|88.6|cin:100176938|COMPASS component SWD3 GO:0007605//sensory perception of sound;GO:0002576//platelet degranulation;GO:0030168//platelet activation GO:0003779//actin binding GO:0005856//cytoskeleton;GO:0005576//extracellular region;GO:0005829//cytosol 610 sp|P07437|TBB5_HUMAN Tubulin beta chain OS=Homo sapiens GN=TUBB PE=1 SV=2 >tr|Q5SU16|Q5SU16_HUMAN Beta 5-tubulin OS=Homo sapiens GN=TUBB PE=2 SV=1 54962 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA 742 32.9 - 43 13 11 3 0.502 0.251 0.278 11 9 8 * * * 0.343666667 0.137783647 sp|P07437|TBB5_HUMAN 100 0 gi|470614409|ref|XP_004316708.1| PREDICTED: tubulin beta chain-like [Tursiops truncatus] 100 0 sp|Q91575|TBB5_XENLA Tubulin beta chain OS=Xenopus laevis GN=tubb PE=2 SV=1 100 0 H9GP30 H9GP30_ANOCA Uncharacterized protein OS=Anolis carolinensis GN=TUBB PE=4 SV=1 ECU03g0820i 749 0 COG5023 Tubulin Z Cytoskeleton ; K07375|1|0.0|856|acs:100563630|tubulin beta GO:0001764//neuron migration;GO:0042267//natural killer cell mediated cytotoxicity;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0051301//cell division;GO:0006184//GTP catabolic process;GO:0051225//spindle assembly;GO:0051258//protein polymerization;GO:0007067//mitosis;GO:0007018//microtubule-based movement;GO:0000086//G2/M transition of mitotic cell cycle;GO:0030182//neuron differentiation GO:0005525//GTP binding;GO:0042288//MHC class I protein binding;GO:0042277//peptide binding;GO:0032403//protein complex binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton GO:0045298//tubulin complex;GO:0044297//cell body;GO:0005641//nuclear envelope lumen;GO:0005829//cytosol;GO:0005874//microtubule 611 sp|P07858|CATB_HUMAN Cathepsin B OS=Homo sapiens GN=CTSB PE=1 SV=3 >tr|A0A024R374|A0A024R374_HUMAN Cathepsin B, isoform CRA_a OS=Homo sapiens GN=CTSB PE=3 SV=1 43633 MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI 2067 51.6 - 124 77 16 12 1.171 1.298 1.445 45 46 43 - - - 1.304666667 0.137121601 sp|P07858|CATB_HUMAN 100 5.00E-149 gi|262368170|pdb|3K9M|A Chain A, Cathepsin B In Complex With Stefin A >gi|262368172|pdb|3K9M|B Chain B, Cathepsin B In Complex With Stefin A 100 0 sp|P07858|CATB_HUMAN Cathepsin B OS=Homo sapiens GN=CTSB PE=1 SV=3 100 3.00E-94 E9PLY3 E9PLY3_HUMAN Cathepsin B (Fragment) OS=Homo sapiens GN=CTSB PE=4 SV=1 AF1946_2 63.2 6.00E-10 COG4870 Cysteine protease O Posttranslational modification, protein turnover, chaperones ; K01363|1|0.0|710|hsa:1508|cathepsin B [EC:3.4.22.1] GO:0009749//response to glucose stimulus;GO:0045471//response to ethanol;GO:0009611//response to wounding;GO:0045087//innate immune response;GO:0006508//proteolysis;GO:0043434//response to peptide hormone stimulus;GO:0007519//skeletal muscle tissue development;GO:0014070//response to organic cyclic compound;GO:0042981//regulation of apoptotic process;GO:0070670//response to interleukin-4;GO:0097067//cellular response to thyroid hormone stimulus;GO:0050790//regulation of catalytic activity;GO:0014075//response to amine stimulus;GO:0060548//negative regulation of cell death;GO:0006914//autophagy;GO:0009612//response to mechanical stimulus GO:0042277//peptide binding;GO:0030984//kininogen binding;GO:0004197//cysteine-type endopeptidase activity GO:0009897//external side of plasma membrane;GO:0005739//mitochondrion;GO:0005901//caveola;GO:0005615//extracellular space;GO:0036021//endolysosome lumen;GO:0042470//melanosome;GO:0048471//perinuclear region of cytoplasm;GO:0016324//apical plasma membrane;GO:0042383//sarcolemma 612 tr|B3GQS7|B3GQS7_HUMAN Mitochondrial heat shock 60kD protein 1 variant 1 OS=Homo sapiens GN=HSPD1 PE=2 SV=1 77240 MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKGKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMF 69 5.8 3 4 4 3 3 1.089 1.119 0.912 2 2 2 - - - 1.04 0.111861522 tr|B3GQS7|B3GQS7_HUMAN 100 0 gi|189502784|gb|ACE06961.1| mitochondrial heat shock 60kD protein 1 variant 1 [Homo sapiens] 99.82 0 sp|P10809|CH60_HUMAN 60 kDa heat shock protein, mitochondrial OS=Homo sapiens GN=HSPD1 PE=1 SV=2 100 0 B3GQS7 B3GQS7_HUMAN Mitochondrial heat shock 60kD protein 1 variant 1 OS=Homo sapiens GN=HSPD1 PE=2 SV=1 SPAC12G12.04 615 9.00E-176 COG0459 Chaperonin GroEL (HSP60 family) O Posttranslational modification, protein turnover, chaperones ; K04077|1|0.0|1075|ptr:459852|chaperonin GroEL GO:0043065//positive regulation of apoptotic process;GO:0032755//positive regulation of interleukin-6 production;GO:0051131//chaperone-mediated protein complex assembly;GO:0042026//protein refolding;GO:0032735//positive regulation of interleukin-12 production;GO:0032729//positive regulation of interferon-gamma production;GO:0043032//positive regulation of macrophage activation;GO:0006458//'de novo' protein folding;GO:0032733//positive regulation of interleukin-10 production;GO:0032727//positive regulation of interferon-alpha production;GO:0006200//ATP catabolic process;GO:0042100//B cell proliferation;GO:0006986//response to unfolded protein;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0019048//virus-host interaction;GO:0002842//positive regulation of T cell mediated immune response to tumor cell;GO:0002368//B cell cytokine production;GO:0050821//protein stabilization;GO:0050870//positive regulation of T cell activation;GO:0051604//protein maturation;GO:0043066//negative regulation of apoptotic process;GO:0048291//isotype switching to IgG isotypes GO:0051087//chaperone binding;GO:0051082//unfolded protein binding;GO:0003697//single-stranded DNA binding;GO:0001530//lipopolysaccharide binding;GO:0002039//p53 binding;GO:0005524//ATP binding;GO:0043498//cell surface binding;GO:0016887//ATPase activity;GO:0003688//DNA replication origin binding GO:0009986//cell surface;GO:0046696//lipopolysaccharide receptor complex;GO:0005829//cytosol;GO:0005759//mitochondrial matrix;GO:0005615//extracellular space;GO:0044459//plasma membrane part;GO:0019907//cyclin-dependent protein kinase activating kinase holoenzyme complex;GO:0005769//early endosome;GO:0030141//secretory granule;GO:0030135//coated vesicle;GO:0005743//mitochondrial inner membrane;GO:0005905//coated pit 613 sp|P24534|EF1B_HUMAN Elongation factor 1-beta OS=Homo sapiens GN=EEF1B2 PE=1 SV=3 >tr|A0A024R3W7|A0A024R3W7_HUMAN Eukaryotic translation elongation factor 1 beta 2, isoform CRA_a OS=Homo sapiens GN=EEF1B2 PE=3 SV=1 31916 MGFGDLKSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEKASLPGVKKALGKYGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKRLREERLAQYESKKAKKPALVAKSSILLDVKPWDDETDMAKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI 145 16.4 - 6 6 3 3 0.822 0.68 0.57 3 3 3 - - * 0.690666667 0.126338171 sp|P24534|EF1B_HUMAN 100 8.00E-45 gi|157830180|pdb|1B64|A Chain A, Solution Structure Of The Guanine Nucleotide Exchange Factor Domain From Human Elongation Factor-One Beta, Nmr, 20 Structures 100 2.00E-100 sp|P24534|EF1B_HUMAN Elongation factor 1-beta OS=Homo sapiens GN=EEF1B2 PE=1 SV=3 100 5.00E-99 G3QVR9 G3QVR9_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla PE=3 SV=1 SPCC1450.04 219 3.00E-57 COG2092 Translation elongation factor EF-1beta J Translation, ribosomal structure and biogenesis ; K03232|1|9e-101|366|ptr:736151|elongation factor 1-beta GO:0006414//translational elongation GO:0003746//translation elongation factor activity;GO:0005515//protein binding GO:0005853//eukaryotic translation elongation factor 1 complex;GO:0005829//cytosol 614 sp|P01008|ANT3_HUMAN Antithrombin-III OS=Homo sapiens GN=SERPINC1 PE=1 SV=1 >tr|A0A024R944|A0A024R944_HUMAN Serpin peptidase inhibitor, clade C (Antithrombin), member 1, isoform CRA_a OS=Homo sapiens GN=SERPINC1 PE=3 SV=1 64585 MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK 2062 35.3 - 105 105 17 17 0.81 2.774 0.956 63 43 38 - * - 1.513333333 1.094207171 sp|P01008|ANT3_HUMAN 100 0 gi|999513|pdb|1ATH|A Chain A, The Intact And Cleaved Human Antithrombin Iii Complex As A Model For Serpin-Proteinase Interactions >gi|1000039|pdb|1ANT|L Chain L, Biological Implications Of A 3 Angstroms Structure Of Dimeric Antithrombin >gi|1000040|pdb|1ANT|I Chain I, Biological Implications Of A 3 Angstroms Structure Of Dimeric Antithrombin >gi|2392667|pdb|2ANT|L Chain L, The 2.6 A Structure Of Antithrombin Indicates A Conformational Change At The Heparin Binding Site >gi|2392668|pdb|2ANT|I Chain I, The 2.6 A Structure Of Antithrombin Indicates A Conformational Change At The Heparin Binding Site >gi|4389345|pdb|1AZX|I Chain I, AntithrombinPENTASACCHARIDE COMPLEX >gi|4389346|pdb|1AZX|L Chain L, AntithrombinPENTASACCHARIDE COMPLEX >gi|6729897|pdb|1BR8|L Chain L, Implications For Function And Therapy Of A 2.9a Structure Of Binary-Complexed Antithrombin >gi|6729898|pdb|1BR8|I Chain I, Implications For Function And Therapy Of A 2.9a Structure Of Binary-Complexed Antithrombin >gi|8569307|pdb|1E03|L Chain L, Plasma Alpha Antithrombin-Iii And Pentasaccharide >gi|8569308|pdb|1E03|I Chain I, Plasma Alpha Antithrombin-Iii And Pentasaccharide >gi|8569309|pdb|1E04|L Chain L, Plasma Beta Antithrombin-Iii >gi|8569310|pdb|1E04|I Chain I, Plasma Beta Antithrombin-Iii >gi|8569311|pdb|1E05|L Chain L, Plasma Alpha Antithrombin-Iii >gi|8569312|pdb|1E05|I Chain I, Plasma Alpha Antithrombin-Iii >gi|8569384|pdb|1DZG|L Chain L, N135q-S380c-Antithrombin-Iii >gi|8569386|pdb|1DZH|L Chain L, P14-Fluorescein-N135q-S380c-Antithrombin-Iii >gi|31615460|pdb|1JVQ|L Chain L, Crystal Structure At 2.6a Of The Ternary Complex Between Antithrombin, A P14-P8 Reactive Loop Peptide, And An Exogenous Tetrapeptide >gi|31615461|pdb|1JVQ|I Chain I, Crystal Structure At 2.6a Of The Ternary Complex Between Antithrombin, A P14-P8 Reactive Loop Peptide, And An Exogenous Tetrapeptide >gi|31615499|pdb|1LK6|L Chain L, Structure Of Dimeric Antithrombin Complexed With A P14-P9 Reactive Loop Peptide And An Exogenous Tripeptide >gi|31615500|pdb|1LK6|I Chain I, Structure Of Dimeric Antithrombin Complexed With A P14-P9 Reactive Loop Peptide And An Exogenous Tripeptide >gi|37926953|pdb|1NQ9|I Chain I, Crystal Structure Of Antithrombin In The Pentasaccharide-Bound Intermediate State >gi|37926954|pdb|1NQ9|L Chain L, Crystal Structure Of Antithrombin In The Pentasaccharide-Bound Intermediate State >gi|48425164|pdb|1OYH|L Chain L, Crystal Structure Of P13 Alanine Variant Of Antithrombin >gi|52695555|pdb|1SR5|A Chain A, Antithrombin-Anhydrothrombin-Heparin Ternary Complex Structure >gi|55669595|pdb|1R1L|L Chain L, Structure Of Dimeric Antithrombin Complexed With A P14-P9 Reactive Loop Peptide And An Exogenous Tripeptide (Formyl-Norleucine-Lf) >gi|55669596|pdb|1R1L|I Chain I, Structure Of Dimeric Antithrombin Complexed With A P14-P9 Reactive Loop Peptide And An Exogenous Tripeptide (Formyl-Norleucine-Lf) >gi|82408098|pdb|2BEH|L Chain L, Crystal Structure Of Antithrombin Variant S137a/v317c/t401c With Plasma Latent Antithrombin >gi|150261272|pdb|2HIJ|L Chain L, Crystal Structure Of P14 Alanine Variant Of Antithrombin >gi|157838181|pdb|1ATH|B Chain B, The Intact And Cleaved Human Antithrombin Iii Complex As A Model For Serpin-Proteinase Interactions >gi|209870303|pdb|2ZNH|A Chain A, Crystal Structure Of A Domain-Swapped Serpin Dimer >gi|209870304|pdb|2ZNH|B Chain B, Crystal Structure Of A Domain-Swapped Serpin Dimer >gi|209870630|pdb|3EVJ|I Chain I, Intermediate Structure Of Antithrombin Bound To The Natural Pentasaccharide >gi|209870631|pdb|3EVJ|L Chain L, Intermediate Structure Of Antithrombin Bound To The Natural Pentasaccharide >gi|395759396|pdb|4EB1|L Chain L, Hyperstable In-Frame Insertion Variant Of Antithrombin 100 0 sp|P01008|ANT3_HUMAN Antithrombin-III OS=Homo sapiens GN=SERPINC1 PE=1 SV=1 99.57 0 H2Q0N0 H2Q0N0_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000117601 PE=3 SV=1 all0778 174 2.00E-43 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K03911|1|0.0|963|hsa:462|antithrombin III GO:0055114//oxidation-reduction process;GO:0007584//response to nutrient;GO:0010951//negative regulation of endopeptidase activity;GO:0006260//DNA replication;GO:0030162//regulation of proteolysis;GO:0007596//blood coagulation;GO:0050728//negative regulation of inflammatory response GO:0004867//serine-type endopeptidase inhibitor activity;GO:0002020//protease binding;GO:0004748//ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor;GO:0008201//heparin binding GO:0005615//extracellular space;GO:0005971//ribonucleoside-diphosphate reductase complex;GO:0005886//plasma membrane 615 tr|A0A024R9Q1|A0A024R9Q1_HUMAN Thrombospondin 1, isoform CRA_a OS=Homo sapiens GN=THBS1 PE=4 SV=1 150297 MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPAPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAGGRLGLFVFSQEMVFFSDLKYECRDP 2114 26.1 - 145 7 27 1 1.617 2.422 2.137 6 6 6 * * * 2.058666667 0.408176841 tr|A0A024R9Q1|A0A024R9Q1_HUMAN 100 0 gi|553801|gb|AAA61237.1| Thrombospondin, partial [Homo sapiens] 99.91 0 sp|P07996|TSP1_HUMAN Thrombospondin-1 OS=Homo sapiens GN=THBS1 PE=1 SV=2 100 0 A0PJG0 A0PJG0_HUMAN THBS1 protein (Fragment) OS=Homo sapiens GN=THBS1 PE=2 SV=1 - - - - - - - K04659|1|0.0|2224|ptr:453319|thrombospondin GO:0016525//negative regulation of angiogenesis;GO:2000462//positive regulation of eukaryotic cell surface binding;GO:0006955//immune response;GO:0043032//positive regulation of macrophage activation;GO:0043652//engulfment of apoptotic cell;GO:0003417//growth plate cartilage development;GO:0045727//positive regulation of translation;GO:0009749//response to glucose stimulus;GO:0002581//negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0045766//positive regulation of angiogenesis;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0032695//negative regulation of interleukin-12 production;GO:0018149//peptide cross-linking;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0010763//positive regulation of fibroblast migration;GO:0051895//negative regulation of focal adhesion assembly;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0030168//platelet activation;GO:0051918//negative regulation of fibrinolysis;GO:0010757//negative regulation of plasminogen activation;GO:0001666//response to hypoxia;GO:0034605//cellular response to heat;GO:0051592//response to calcium ion;GO:0010811//positive regulation of cell-substrate adhesion;GO:0010748//negative regulation of plasma membrane long-chain fatty acid transport;GO:0001937//negative regulation of endothelial cell proliferation;GO:0032026//response to magnesium ion;GO:0002576//platelet degranulation;GO:0010754//negative regulation of cGMP-mediated signaling;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0032570//response to progesterone stimulus;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0002544//chronic inflammatory response;GO:0007050//cell cycle arrest;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0002605//negative regulation of dendritic cell antigen processing and presentation;GO:0051897//positive regulation of protein kinase B signaling cascade;GO:0000187//activation of MAPK activity;GO:0042493//response to drug;GO:0002040//sprouting angiogenesis;GO:0010759//positive regulation of macrophage chemotaxis;GO:0006917//induction of apoptosis GO:0070051//fibrinogen binding;GO:0008201//heparin binding;GO:0070052//collagen V binding;GO:0005178//integrin binding;GO:0017134//fibroblast growth factor binding;GO:0001968//fibronectin binding;GO:0042802//identical protein binding;GO:0030169//low-density lipoprotein particle binding;GO:0001786//phosphatidylserine binding;GO:0043499//eukaryotic cell surface binding;GO:0050431//transforming growth factor beta binding;GO:0005509//calcium ion binding;GO:0043394//proteoglycan binding;GO:0043236//laminin binding GO:0005577//fibrinogen complex;GO:0009897//external side of plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0031012//extracellular matrix 616 tr|Q6I9U9|Q6I9U9_HUMAN LGMN protein OS=Homo sapiens GN=LGMN PE=2 SV=1 57326 MVWKVAVFLSVALGIGAVPIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIVINRPNGTGVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPDVPLTIMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY 105 6.5 4 4 4 2 2 1.217 1.061 1.808 4 4 3 - - * 1.362 0.394044414 tr|Q6I9U9|Q6I9U9_HUMAN 100 8.00E-94 gi|15489140|gb|AAH13678.1| Unknown (protein for IMAGE:3856715), partial [Homo sapiens] 99.77 0 sp|Q99538|LGMN_HUMAN Legumain OS=Homo sapiens GN=LGMN PE=1 SV=1 100 3.00E-93 Q96CY7 Q96CY7_HUMAN Putative uncharacterized protein (Fragment) OS=Homo sapiens PE=2 SV=1 YDR331w 113 5.00E-25 COG5206 Glycosylphosphatidylinositol transamidase (GPIT), subunit GPI8 O Posttranslational modification, protein turnover, chaperones ; K01369|1|0.0|907|hsa:5641|legumain [EC:3.4.22.34] GO:0001101//response to acid;GO:0045087//innate immune response;GO:0042359//vitamin D metabolic process;GO:0006508//proteolysis;GO:0043524//negative regulation of neuron apoptotic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0040015//negative regulation of multicellular organism growth GO:0004197//cysteine-type endopeptidase activity GO:0043202//lysosomal lumen;GO:0005770//late endosome;GO:0045177//apical part of cell 617 tr|Q59E93|Q59E93_HUMAN Membrane alanine aminopeptidase variant (Fragment) OS=Homo sapiens PE=2 SV=1 124916 GSLSRLPTITMAKGFYISKSLGILGILLGVAAVCTIIALSVVYSQEKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYNEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWFTENSK 738 14.7 1 51 51 14 14 0.65 0.757 0.664 29 29 27 * * * 0.690333333 0.058157831 tr|Q59E93|Q59E93_HUMAN 100 0 gi|62089422|dbj|BAD93155.1| membrane alanine aminopeptidase precursor variant [Homo sapiens] 99.9 0 sp|P15144|AMPN_HUMAN Aminopeptidase N OS=Homo sapiens GN=ANPEP PE=1 SV=4 100 0 Q59E93 Q59E93_HUMAN Membrane alanine aminopeptidase variant (Fragment) OS=Homo sapiens PE=2 SV=1 YHR047c 393 1.00E-108 COG0308 Aminopeptidase N E Amino acid transport and metabolism ; K11140|1|0.0|1875|hsa:290|aminopeptidase N [EC:3.4.11.2] GO:0001525//angiogenesis;GO:0035814//negative regulation of renal sodium excretion;GO:0006508//proteolysis;GO:0030154//cell differentiation;GO:0006725//cellular aromatic compound metabolic process;GO:0019048//virus-host interaction GO:0042277//peptide binding;GO:0008270//zinc ion binding;GO:0004872//receptor activity;GO:0004177//aminopeptidase activity;GO:0008237//metallopeptidase activity GO:0031983//vesicle lumen;GO:0005829//cytosol;GO:0009897//external side of plasma membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0012506//vesicle membrane;GO:0005887//integral to plasma membrane 618 tr|J3KPM9|J3KPM9_HUMAN Signal transducer and activator of transcription OS=Homo sapiens GN=STAT1 PE=1 SV=1 100913 MWMSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDLLSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKILENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKTLQNREHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLNVTELTQNALINDELVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPITKNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGLIPWTRFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEV 83 6.6 1 5 5 4 4 0.362 1.003 0.49 2 2 2 - - - 0.618333333 0.339223132 tr|J3KPM9|J3KPM9_HUMAN 100 0 gi|62738788|pdb|1YVL|A Chain A, Structure Of Unphosphorylated Stat1 >gi|62738789|pdb|1YVL|B Chain B, Structure Of Unphosphorylated Stat1 100 0 sp|P42224|STAT1_HUMAN Signal transducer and activator of transcription 1-alpha/beta OS=Homo sapiens GN=STAT1 PE=1 SV=2 100 0 H2P855 H2P855_PONAB Uncharacterized protein OS=Pongo abelii GN=STAT1 PE=4 SV=1 - - - - - - - K11220|1|0.0|1447|hsa:6772|signal transducer and activator of transcription 1 GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0016525//negative regulation of angiogenesis;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0007584//response to nutrient;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0043330//response to exogenous dsRNA;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB cascade;GO:0043542//endothelial cell migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001937//negative regulation of endothelial cell proliferation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032869//cellular response to insulin stimulus;GO:0019048//virus-host interaction;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0072308//negative regulation of metanephric nephron tubule epithelial cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051591//response to cAMP;GO:0072136//metanephric mesenchymal cell proliferation involved in metanephros development;GO:0009615//response to virus;GO:0008015//blood circulation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0072162//metanephric mesenchymal cell differentiation;GO:0003340//negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0006917//induction of apoptosis GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0004871//signal transducer activity;GO:0042803//protein homodimerization activity;GO:0000983//RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity;GO:0003690//double-stranded DNA binding;GO:0005509//calcium ion binding;GO:0019899//enzyme binding;GO:0005164//tumor necrosis factor receptor binding GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0030424//axon;GO:0030425//dendrite;GO:0005730//nucleolus 619 tr|B2R9H3|B2R9H3_HUMAN cDNA, FLJ94391, highly similar to Homo sapiens serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8 (SERPINB8), mRNA OS=Homo sapiens PE=2 SV=1 53032 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQSLCLYKDGDIHQGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 96 16.3 1 9 6 6 4 1.958 1.346 1.866 3 2 3 * - - 1.723333333 0.33000202 tr|B2R9H3|B2R9H3_HUMAN 100 1.00E-97 gi|451770404|ref|NP_001263419.1| serpin B8 isoform c [Homo sapiens] 99.47 0 sp|P50452|SPB8_HUMAN Serpin B8 OS=Homo sapiens GN=SERPINB8 PE=1 SV=2 100 0 B2R9H3 B2R9H3_HUMAN cDNA, FLJ94391, highly similar to Homo sapiens serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8 (SERPINB8), mRNA OS=Homo sapiens PE=2 SV=1 all0778 207 2.00E-53 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K13963|1|0.0|734|ptr:455461|serpin B GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding GO:0005829//cytosol 620 sp|P30086|PEBP1_HUMAN Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens GN=PEBP1 PE=1 SV=3 >tr|D9IAI1|D9IAI1_HUMAN Epididymis secretory protein Li 34 OS=Homo sapiens GN=PEBP1 PE=2 SV=1 26025 MPVDLSKWSGPLSLQEVDEQPQHPLHVTYAGAAVDELGKVLTPTQVKNRPTSISWDGLDSGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTVLSDYVGSGPPKGTGLHRYVWLVYEQDRPLKCDEPILSNRSGDHRGKFKVASFRKKYELRAPVAGTCYQAEWDDYVPKLYEQLSGK 645 43.3 - 41 41 6 6 0.761 0.665 0.668 24 24 24 - * * 0.698 0.054580216 sp|P30086|PEBP1_HUMAN 100 8.00E-78 gi|4261934|gb|AAD14234.1|S76773_1 neuropolypeptide h3, partial [Homo sapiens] 100 8.00E-107 sp|P30086|PEBP1_HUMAN Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens GN=PEBP1 PE=1 SV=3 100 2.00E-105 H2Q6Z4 H2Q6Z4_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000089220 PE=4 SV=1 YLR178c 62.8 3.00E-10 COG1881 Phospholipid-binding protein R General function prediction only ; K14802|1|2e-08|58.5|dan:Dana_GF11187|phospholipid-transporting ATPase [EC:3.6.3.1] GO:0009611//response to wounding;GO:0051602//response to electrical stimulus;GO:0010243//response to organic nitrogen;GO:0051412//response to corticosterone stimulus;GO:0014823//response to activity;GO:0045471//response to ethanol;GO:0042755//eating behavior;GO:0051592//response to calcium ion;GO:0007568//aging;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0001933//negative regulation of protein phosphorylation;GO:0007420//brain development;GO:0014070//response to organic cyclic compound;GO:0043409//negative regulation of MAPK cascade;GO:0007286//spermatid development;GO:0042493//response to drug;GO:0051591//response to cAMP;GO:0009408//response to heat;GO:0045840//positive regulation of mitosis;GO:0009636//response to toxic substance;GO:0002026//regulation of the force of heart contraction;GO:0060409//positive regulation of acetylcholine metabolic process;GO:0006979//response to oxidative stress;GO:0010466//negative regulation of peptidase activity GO:0051019//mitogen-activated protein kinase binding;GO:0005102//receptor binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008429//phosphatidylethanolamine binding;GO:0005524//ATP binding GO:0043679//axon terminus;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005741//mitochondrial outer membrane;GO:0009986//cell surface;GO:0043025//neuronal cell body;GO:0008021//synaptic vesicle;GO:0045177//apical part of cell;GO:0005791//rough endoplasmic reticulum 621 sp|P35241|RADI_HUMAN Radixin OS=Homo sapiens GN=RDX PE=1 SV=1 >tr|B0YJ88|B0YJ88_HUMAN Radixin OS=Homo sapiens GN=RDX PE=2 SV=1 89321 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 439 17.3 - 53 5 10 4 0.758 0.722 0.795 3 3 3 - - - 0.758333333 0.036501142 sp|P35241|RADI_HUMAN 100 0 gi|99032011|pdb|2D2Q|A Chain A, Crystal Structure Of The Dimerized Radixin Ferm Domain >gi|99032012|pdb|2D2Q|B Chain B, Crystal Structure Of The Dimerized Radixin Ferm Domain 100 0 sp|P35241|RADI_HUMAN Radixin OS=Homo sapiens GN=RDX PE=1 SV=1 100 0 H2NF82 H2NF82_PONAB Uncharacterized protein OS=Pongo abelii GN=RDX PE=4 SV=1 - - - - - - - K05762|1|0.0|936|hsa:5962|radixin GO:0045176//apical protein localization;GO:0030033//microvillus assembly;GO:0051693//actin filament capping GO:0003779//actin binding GO:0030175//filopodium;GO:0019898//extrinsic to membrane;GO:0032420//stereocilium;GO:0001726//ruffle;GO:0005856//cytoskeleton;GO:0005730//nucleolus;GO:0032154//cleavage furrow;GO:0005925//focal adhesion;GO:0030027//lamellipodium;GO:0045177//apical part of cell;GO:0005794//Golgi apparatus 622 tr|B3KNN9|B3KNN9_HUMAN cDNA FLJ30070 fis, clone ASTRO2000046, highly similar to CD166 ANTIGEN OS=Homo sapiens PE=2 SV=1 75362 MESKGASSCRLLFCLLISATVFRPGLGWYTVNSAYGDTIIIPCRLDVPQNLMFGKWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKDRLNLSENYTLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTYTLMDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGDALPVSCTISASRNATVVWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQEVEGLKKRESLTLIVEGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSLNVSAISIPEHDEADEISDENREKVNDQAKLIVGIVVGLLLAALVAGVVYWLYMKKSK 62 6.3 3 4 4 3 3 0.348 0.314 0.384 3 3 3 - * - 0.348666667 0.035004762 tr|B3KNN9|B3KNN9_HUMAN 100 6.00E-21 gi|213495854|gb|ACJ49147.1| activated leukocyte cell adhesion molecule [Mustela putorius furo] 99.82 0 sp|Q13740|CD166_HUMAN CD166 antigen OS=Homo sapiens GN=ALCAM PE=1 SV=2 100 1.00E-163 B4DX43 B4DX43_HUMAN cDNA FLJ52980, highly similar to CD166 antigen OS=Homo sapiens PE=2 SV=1 - - - - - - - K06547|1|0.0|1105|hsa:214|activated leukocyte cell adhesion molecule GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0008045//motor neuron axon guidance GO:0005102//receptor binding GO:0030424//axon;GO:0009897//external side of plasma membrane;GO:0016021//integral to membrane;GO:0043025//neuronal cell body 623 sp|P23396|RS3_HUMAN 40S ribosomal protein S3 OS=Homo sapiens GN=RPS3 PE=1 SV=2 33231 MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDPTGKIGPKKPLPDHVSIVEPKDEILPTTPISEQKGGKPEPPAMPQPVPTA 98 16 - 4 4 3 3 1.012 0.529 --- 2 2 1 - - - 0.7705 0.341532575 sp|P23396|RS3_HUMAN 100 3.00E-87 gi|9022435|gb|AAF82383.1|AF281313_1 ribosomal protein S3 [Homo sapiens] 100 2.00E-138 sp|P23396|RS3_HUMAN 40S ribosomal protein S3 OS=Homo sapiens GN=RPS3 PE=1 SV=2 100 1.00E-105 G1S4V5 G1S4V5_NOMLE Uncharacterized protein (Fragment) OS=Nomascus leucogenys GN=RPS3 PE=3 SV=1 SPBC16G5.14c 325 5.00E-89 COG0092 Ribosomal protein S3 J Translation, ribosomal structure and biogenesis ; K02985|1|2e-138|491|ptr:100610616|small subunit ribosomal protein S3e GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006415//translational termination;GO:0006413//translational initiation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006414//translational elongation;GO:0045738//negative regulation of DNA repair;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0006917//induction of apoptosis;GO:0019083//viral transcription;GO:0006614//SRP-dependent cotranslational protein targeting to membrane GO:0003684//damaged DNA binding;GO:0019901//protein kinase binding;GO:0051536//iron-sulfur cluster binding;GO:0051059//NF-kappaB binding;GO:0004519//endonuclease activity;GO:0003735//structural constituent of ribosome;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0003729//mRNA binding GO:0032587//ruffle membrane;GO:0030425//dendrite;GO:0012505//endomembrane system;GO:0005634//nucleus;GO:0022627//cytosolic small ribosomal subunit 624 sp|P46108|CRK_HUMAN Adapter molecule crk OS=Homo sapiens GN=CRK PE=1 SV=2 >tr|L7RT18|L7RT18_HUMAN V-crk sarcoma virus CT10 oncogene homolog (Avian) OS=Homo sapiens GN=CRK PE=4 SV=1 37518 MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSRSRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYAQPSVNTPLPNLQNGPIYARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGECNGKRGHFPFTHVRLLDQQNPDEDFS 104 12.8 - 7 7 3 3 1.137 0.946 0.883 2 2 2 - - - 0.988666667 0.132266146 sp|P46108|CRK_HUMAN 100 5.00E-158 gi|344240627|gb|EGV96730.1| Proto-oncogene C-crk [Cricetulus griseus] 100 1.00E-161 sp|P46108|CRK_HUMAN Adapter molecule crk OS=Homo sapiens GN=CRK PE=1 SV=2 100 9.00E-97 H9FQ53 H9FQ53_MACMU Adapter molecule crk isoform b OS=Macaca mulatta GN=CRK PE=2 SV=1 - - - - - - - K04438|1|3e-162|571|ecb:100072356|proto-oncogene C-crk GO:0051270//regulation of cellular component movement;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0030168//platelet activation;GO:0008286//insulin receptor signaling pathway;GO:0000186//activation of MAPKK activity;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007257//activation of JUN kinase activity;GO:0048013//ephrin receptor signaling pathway;GO:0032956//regulation of actin cytoskeleton organization;GO:0035020//regulation of Rac protein signal transduction;GO:0032319//regulation of Rho GTPase activity GO:0046875//ephrin receptor binding;GO:0042169//SH2 domain binding;GO:0005070//SH3/SH2 adaptor activity;GO:0045309//protein phosphorylated amino acid binding GO:0005829//cytosol;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005634//nucleus 625 tr|B4DKJ4|B4DKJ4_HUMAN cDNA FLJ57738, highly similar to Translationally-controlled tumor protein OS=Homo sapiens PE=2 SV=1 19250 MIIYRDLISHDEMFSDIYKIREIADGLCLEVEGKMVSRTEGNIDDSLIGGNASAEGPEGEGTESTVITGVDIVMNHHLQETSFTKEAYKKYIKHILANFKNYQFFIGENMNPDGMVALLDYREDGVTPYMIFFKDGLEMEKC 226 27.5 2 9 9 3 3 0.812 0.718 0.643 7 8 8 - - * 0.724333333 0.084677821 tr|B4DKJ4|B4DKJ4_HUMAN 100 2.00E-78 gi|194383696|dbj|BAG59206.1| unnamed protein product [Homo sapiens] 82.56 8.00E-75 sp|A5A6K2|TCTP_PANTR Translationally-controlled tumor protein OS=Pan troglodytes GN=TPT1 PE=2 SV=1 100 3.00E-24 Q9NXW1 Q9NXW1_HUMAN BJ-HCC-24 tumor antigen OS=Homo sapiens PE=2 SV=1 - - - - - - - - GO:0009615//response to virus;GO:2000384//negative regulation of ectoderm development;GO:0006874//cellular calcium ion homeostasis;GO:0019827//stem cell maintenance;GO:0006816//calcium ion transport GO:0005509//calcium ion binding;GO:0008134//transcription factor binding GO:0005771//multivesicular body;GO:0045298//tubulin complex;GO:0005615//extracellular space;GO:0005654//nucleoplasm 626 tr|B4DPC7|B4DPC7_HUMAN cDNA FLJ55124, highly similar to Plasma serine protease inhibitor OS=Homo sapiens PE=2 SV=1 43977 MQLFLLLCLVLLSPQGASLNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNILFLGKVNRP 140 7.6 1 5 5 2 2 1.034 3.417 --- 3 3 1 - - - 2.2255 1.68503546 tr|B4DPC7|B4DPC7_HUMAN 100 0 gi|194390046|dbj|BAG60539.1| unnamed protein product [Homo sapiens] 99.04 0 sp|P05154|IPSP_HUMAN Plasma serine protease inhibitor OS=Homo sapiens GN=SERPINA5 PE=1 SV=3 100 7.00E-151 F5H6K7 F5H6K7_HUMAN Plasma serine protease inhibitor OS=Homo sapiens GN=SERPINA5 PE=3 SV=1 all0778 170 4.00E-42 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K03913|1|0.0|646|hsa:5104|protein C inhibitor GO:0010951//negative regulation of endopeptidase activity;GO:0006869//lipid transport;GO:0007283//spermatogenesis;GO:0045861//negative regulation of proteolysis;GO:0007342//fusion of sperm to egg plasma membrane GO:0001972//retinoic acid binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008201//heparin binding;GO:0032190//acrosin binding;GO:0031210//phosphatidylcholine binding;GO:0002020//protease binding GO:0097183//protein C inhibitor-coagulation factor XI complex;GO:0036030//protein C inhibitor-plasma kallikrein complex;GO:0036024//protein C inhibitor-TMPRSS7 complex;GO:0036026//protein C inhibitor-PLAT complex;GO:0005615//extracellular space;GO:0031091//platelet alpha granule;GO:0031094//platelet dense tubular network;GO:0036029//protein C inhibitor-KLK3 complex;GO:0009897//external side of plasma membrane;GO:0036027//protein C inhibitor-PLAU complex;GO:0097181//protein C inhibitor-coagulation factor V complex;GO:0036025//protein C inhibitor-TMPRSS11E complex;GO:0097182//protein C inhibitor-coagulation factor Xa complex;GO:0036028//protein C inhibitor-thrombin complex;GO:0002080//acrosomal membrane 627 sp|P06733|ENOA_HUMAN Alpha-enolase OS=Homo sapiens GN=ENO1 PE=1 SV=2 >tr|A0A024R4F1|A0A024R4F1_HUMAN Enolase 1, (Alpha), isoform CRA_a OS=Homo sapiens GN=ENO1 PE=3 SV=1 59345 MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVVIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFRNPLAK 2968 38.7 - 127 108 13 11 0.888 0.733 0.752 81 80 82 * * * 0.791 0.084539931 sp|P06733|ENOA_HUMAN 100 0 gi|203282367|pdb|3B97|A Chain A, Crystal Structure Of Human Enolase 1 >gi|203282368|pdb|3B97|B Chain B, Crystal Structure Of Human Enolase 1 >gi|203282369|pdb|3B97|C Chain C, Crystal Structure Of Human Enolase 1 >gi|203282370|pdb|3B97|D Chain D, Crystal Structure Of Human Enolase 1 100 0 sp|P06733|ENOA_HUMAN Alpha-enolase OS=Homo sapiens GN=ENO1 PE=1 SV=2 100 0 G2HFA5 G2HFA5_PANTR Alpha-enolase OS=Pan troglodytes GN=ENSG00000074800 PE=2 SV=1 YGR254w 567 1.00E-161 COG0148 Enolase G Carbohydrate transport and metabolism ; K01689|1|0.0|893|ptr:457913|enolase [EC:4.2.1.11] GO:0009615//response to virus;GO:0030308//negative regulation of cell growth;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006096//glycolysis;GO:0006094//gluconeogenesis;GO:0044281//small molecule metabolic process GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0000287//magnesium ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0004634//phosphopyruvate hydratase activity GO:0031430//M band;GO:0000015//phosphopyruvate hydratase complex;GO:0009986//cell surface;GO:0005634//nucleus;GO:0005886//plasma membrane 628 tr|A0A087WY71|A0A087WY71_HUMAN AP-2 complex subunit mu OS=Homo sapiens GN=AP2M1 PE=1 SV=1 61701 MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFITQQGIKSQHTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC 75 8.5 3 4 4 4 4 0.973 0.713 0.659 3 3 3 - - - 0.781666667 0.167884881 tr|A0A087WY71|A0A087WY71_HUMAN 100 7.00E-159 gi|17942841|pdb|1H6E|A Chain A, Mu2 Adaptin Subunit (Ap50) Of Ap2 Adaptor (Second Domain), Complexed With Ctla-4 Internalization Peptide Ttgvyvkmppt 99.77 0 sp|P84092|AP2M1_RAT AP-2 complex subunit mu OS=Rattus norvegicus GN=Ap2m1 PE=1 SV=1 99.77 0 G1SM15 G1SM15_RABIT Uncharacterized protein OS=Oryctolagus cuniculus GN=AP2M1 PE=4 SV=1 - - - - - - - K11826|1|0.0|897|bta:517446|AP-2 complex subunit mu-1 GO:0007411//axon guidance;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0016032//viral reproduction;GO:0016044//cellular membrane organization;GO:0006886//intracellular protein transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050690//regulation of defense response to virus by virus;GO:0016192//vesicle-mediated transport;GO:0007268//synaptic transmission GO:0005515//protein binding;GO:0005215//transporter activity;GO:0008289//lipid binding GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0030132//clathrin coat of coated pit;GO:0030133//transport vesicle;GO:0030131//clathrin adaptor complex;GO:0030141//secretory granule;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0030125//clathrin vesicle coat;GO:0005739//mitochondrion 629 tr|B4E2S7|B4E2S7_HUMAN cDNA FLJ58780, highly similar to Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant LAMP2B, mRNA OS=Homo sapiens PE=2 SV=1 45662 MNFTVRYETTNKTYKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNTGDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNGTVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQLNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVNISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQGKYSTAQECSLDDDTILIPIIVGAGLSGLIIVIVIAYVIGRRKSYAGYQTL 169 8 1 11 11 3 3 1.55 1.197 1.03 5 6 6 - - - 1.259 0.265486346 tr|B4E2S7|B4E2S7_HUMAN 100 3.00E-08 gi|194375932|dbj|BAG57310.1| unnamed protein product [Homo sapiens] 94.18 0 sp|P13473|LAMP2_HUMAN Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens GN=LAMP2 PE=1 SV=2 100 6.00E-129 H0YCG2 H0YCG2_HUMAN Lysosome-associated membrane glycoprotein 2 (Fragment) OS=Homo sapiens GN=LAMP2 PE=4 SV=1 - - - - - - - K06528|1|0.0|679|pon:100438981|lysosomal-associated membrane protein 1/2 GO:0030168//platelet activation;GO:0002576//platelet degranulation - GO:0005765//lysosomal membrane;GO:0030670//phagocytic vesicle membrane;GO:0016021//integral to membrane;GO:0031088//platelet dense granule membrane;GO:0031902//late endosome membrane;GO:0005886//plasma membrane 630 tr|B2R7N9|B2R7N9_HUMAN cDNA, FLJ93532, highly similar to Homo sapiens osteomodulin (OMD), mRNA OS=Homo sapiens PE=2 SV=1 57509 MGFLSPIYVIFFFFGVKVHCQYETYQWDEDYDQEPDDDYQTGFPFRQNVDYGVPFHQYTLGCVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPLHYHHLTYIRVDQNKLKEPISSYIFFCFPHIHTIYYGEQRSTNGQTIQLKTQVFSRFPDDDDESEDHDDPDNAHESPEQEGAEGHFDLHYYENQE 90 10 1 10 10 4 4 --- 4.1 --- 1 2 1 - - - 4.1 - tr|B2R7N9|B2R7N9_HUMAN 100 0 gi|189053634|dbj|BAG35886.1| unnamed protein product [Homo sapiens] 99.76 0 sp|Q99983|OMD_HUMAN Osteomodulin OS=Homo sapiens GN=OMD PE=1 SV=1 100 0 B2R7N9 B2R7N9_HUMAN cDNA, FLJ93532, highly similar to Homo sapiens osteomodulin (OMD), mRNA OS=Homo sapiens PE=2 SV=1 alr0124_1 85.5 2.00E-16 COG4886 Leucine-rich repeat (LRR) protein S Function unknown ; K08124|1|0.0|760|hsa:4958|osteomodulin GO:0042340//keratan sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0018146//keratan sulfate biosynthetic process;GO:0044281//small molecule metabolic process;GO:0007155//cell adhesion - GO:0043202//lysosomal lumen;GO:0005796//Golgi lumen;GO:0005578//proteinaceous extracellular matrix 631 sp|Q9UDY4|DNJB4_HUMAN DnaJ homolog subfamily B member 4 OS=Homo sapiens GN=DNAJB4 PE=1 SV=1 47746 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGRDSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPVIHELRVSLEEIYSGCTKRMKISRKRLNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKDHPKFKRDGSNIIYTAKISLREALCGCSINVPTLDGRNIPMSVNDIVKPGMRRRIIGYGLPFPKNPDQRGDLLIEFEVSFPDTISSSSKEVLRKHLPAS 83 11 2 5 5 3 3 0.284 0.361 0.277 2 2 2 * * * 0.307333333 0.046608297 sp|Q9UDY4|DNJB4_HUMAN 100 2.00E-125 gi|119626760|gb|EAX06355.1| DnaJ (Hsp40) homolog, subfamily B, member 4, isoform CRA_b [Homo sapiens] 100 0 sp|Q9UDY4|DNJB4_HUMAN DnaJ homolog subfamily B member 4 OS=Homo sapiens GN=DNAJB4 PE=1 SV=1 100 7.00E-125 B4DNN2 B4DNN2_HUMAN DnaJ (Hsp40) homolog, subfamily B, member 4, isoform CRA_b OS=Homo sapiens GN=DNAJB4 PE=2 SV=1 slr0093 150 4.00E-36 COG2214 DnaJ-class molecular chaperone O Posttranslational modification, protein turnover, chaperones ; K09510|1|0.0|647|ptr:100608554|DnaJ homolog subfamily B member 4 GO:0006457//protein folding;GO:0006986//response to unfolded protein;GO:0009408//response to heat GO:0031072//heat shock protein binding;GO:0051082//unfolded protein binding GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane 632 tr|B4DHQ3|B4DHQ3_HUMAN Phosphoserine aminotransferase OS=Homo sapiens PE=2 SV=1 54300 MGRRLGAGTRRGFGAGCRLSPQRPGTPAVHAFGPPWLTHRPRRRTMDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCGQFSAVPLNLIGLKAGRCADYVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGAVLVCDMSSNFLSKPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSIYVMGLVLEWIKNNGGAAAMEKLSSIKSQTIYEIIDNSQGFYVCPVEPQNRSKMNIPFRIGNAKGDDALEKRFLDKALELNMLSLKGHRSVGGIRASLYNAVTIEDVQKLAAFMKKFLEMHQL 484 23.4 1 29 29 9 9 1.338 1.568 1.226 22 22 21 * * * 1.377333333 0.174359781 tr|B4DHQ3|B4DHQ3_HUMAN 100 0 gi|17402893|ref|NP_478059.1| phosphoserine aminotransferase isoform 1 [Homo sapiens] >gi|20141815|sp|Q9Y617.2|SERC_HUMAN RecName: Full=Phosphoserine aminotransferase; AltName: Full=Phosphohydroxythreonine aminotransferase; Short=PSAT >gi|12654301|gb|AAH00971.1| Phosphoserine aminotransferase 1 [Homo sapiens] >gi|13436074|gb|AAH04863.1| Phosphoserine aminotransferase 1 [Homo sapiens] >gi|17390289|gb|AAH18129.1| Phosphoserine aminotransferase 1 [Homo sapiens] >gi|25140375|gb|AAN71736.1| phosphoserine aminotransferase [Homo sapiens] >gi|30582519|gb|AAP35486.1| phosphoserine aminotransferase [Homo sapiens] >gi|119583025|gb|EAW62621.1| phosphoserine aminotransferase 1, isoform CRA_d [Homo sapiens] >gi|119583026|gb|EAW62622.1| phosphoserine aminotransferase 1, isoform CRA_d [Homo sapiens] 100 0 sp|Q9Y617|SERC_HUMAN Phosphoserine aminotransferase OS=Homo sapiens GN=PSAT1 PE=1 SV=2 100 1.00E-10 H2QXD6 H2QXD6_PANTR Uncharacterized protein OS=Pan troglodytes GN=PSAT1 PE=3 SV=1 PA3167 375 7.00E-104 COG1932 Phosphoserine aminotransferase HE Coenzyme transport and metabolism ; Amino acid transport and metabolism ; K00831|1|0.0|830|pon:100459045|phosphoserine aminotransferase [EC:2.6.1.52] GO:0034641//cellular nitrogen compound metabolic process;GO:0006564//L-serine biosynthetic process;GO:0008615//pyridoxine biosynthetic process GO:0030170//pyridoxal phosphate binding;GO:0004648//O-phospho-L-serine:2-oxoglutarate aminotransferase activity GO:0005829//cytosol 633 tr|B2RDN9|B2RDN9_HUMAN cDNA, FLJ96699, highly similar to Homo sapiens thyroid autoantigen 70kDa (Ku antigen) (G22P1), mRNA OS=Homo sapiens PE=2 SV=1 88279 MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIVLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVHPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD 116 5.3 1 5 5 3 3 1.007 0.681 0.976 3 3 3 - - - 0.888 0.1799361 tr|B2RDN9|B2RDN9_HUMAN 100 0 gi|189055002|dbj|BAG37986.1| unnamed protein product [Homo sapiens] 99.67 0 sp|P12956|XRCC6_HUMAN X-ray repair cross-complementing protein 6 OS=Homo sapiens GN=XRCC6 PE=1 SV=2 100 0 B2RDN9 B2RDN9_HUMAN cDNA, FLJ96699, highly similar to Homo sapiens thyroid autoantigen 70kDa (Ku antigen) (G22P1), mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K10884|1|0.0|1115|hsa:2547|ATP-dependent DNA helicase 2 subunit 1 GO:0050769//positive regulation of neurogenesis;GO:0016032//viral reproduction;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0045892//negative regulation of transcription, DNA-dependent;GO:0033151//V(D)J recombination;GO:0006266//DNA ligation;GO:0000723//telomere maintenance;GO:0010212//response to ionizing radiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter GO:0008022//protein C-terminus binding;GO:0044212//transcription regulatory region DNA binding;GO:0003691//double-stranded telomeric DNA binding;GO:0051575//5'-deoxyribose-5-phosphate lyase activity;GO:0004003//ATP-dependent DNA helicase activity;GO:0005524//ATP binding GO:0016020//membrane;GO:0005958//DNA-dependent protein kinase-DNA ligase 4 complex;GO:0005737//cytoplasm;GO:0005667//transcription factor complex;GO:0043564//Ku70:Ku80 complex;GO:0000783//nuclear telomere cap complex 634 tr|A0A024R872|A0A024R872_HUMAN Chromosome 9 open reading frame 88, isoform CRA_a OS=Homo sapiens GN=C9orf88 PE=4 SV=1 96529 MGWMGEKTGKILTEFLQFYEDQYGVALFNSMRHEIEGTGLPQAQLLWRKVPLDERIVFSGNLFQHQEDSKKWRNRFSLVPHNYGLVLYENKAAYERQVPPRAVINSAGYKILTSVDQYLELIGNSLPGTTAKSGSAPILKCPTQFPLILWHPYARHYYFCMMTEAEQDKWQAVLQDCIRHCNNGIPEDSKVEGPAFTDAIRMYRQSKELYGTWEMLCGNEVQILSNLVMEELGPELKAELGPRLKGKPQERQRQWIQISDAVYHMVYEQAKARFEEVLSKVQQVQPAMQAVIRTDMDQIITSKEHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQGFTEVRDVFFKEVTDMNLNVINEGGIDKLGEYMEKLSRLAYHPLKMQSCYEKMESLRLDGLQQRFDVSSTSVFKQRAQIHMREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRVLERVLKKYDYDSSSVRKRFFREALLQISIPFLLKKLAPTCKSELPRFQELIFEDFARFILVENTYEEVVLQTVMKDILQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGEEYSNSGGGGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSSPSSHPALHTTTEDSAGVQTEF 51 6.1 1 4 4 3 3 0.66 1.454 0.887 2 2 2 - - - 1.000333333 0.408952728 tr|A0A024R872|A0A024R872_HUMAN 100 0 gi|6808243|emb|CAB70809.1| hypothetical protein [Homo sapiens] 99.73 0 sp|Q96TA1|NIBL1_HUMAN Niban-like protein 1 OS=Homo sapiens GN=FAM129B PE=1 SV=3 100 0 F5H3T0 F5H3T0_HUMAN Niban-like protein 1 OS=Homo sapiens GN=FAM129B PE=4 SV=1 - - - - - - - - GO:0043066//negative regulation of apoptotic process GO:0005543//phospholipid binding GO:0005912//adherens junction;GO:0005634//nucleus;GO:0005829//cytosol 635 sp|P02462|CO4A1_HUMAN Collagen alpha-1(IV) chain OS=Homo sapiens GN=COL4A1 PE=1 SV=3 190250 MGPRLSVWLLLLPAALLLHEEHSRAAAKGGCAGSGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMRRT 157 3.9 - 6 6 3 3 0.792 0.577 0.606 4 3 2 - - - 0.658333333 0.116663333 sp|P02462|CO4A1_HUMAN 100 7.00E-142 gi|397524284|ref|XP_003832130.1| PREDICTED: collagen alpha-1(IV) chain [Pan paniscus] 100 8.00E-143 sp|P02462|CO4A1_HUMAN Collagen alpha-1(IV) chain OS=Homo sapiens GN=COL4A1 PE=1 SV=3 100 8.00E-06 H2NKA6 H2NKA6_PONAB Uncharacterized protein OS=Pongo abelii GN=LOC100444160 PE=4 SV=1 - - - - - - - K06237|1|8e-143|509|hsa:1282|collagen, type IV, alpha GO:0007411//axon guidance;GO:0001525//angiogenesis;GO:0007528//neuromuscular junction development;GO:0030855//epithelial cell differentiation;GO:0071230//cellular response to amino acid stimulus;GO:0030198//extracellular matrix organization GO:0048407//platelet-derived growth factor binding;GO:0005201//extracellular matrix structural constituent GO:0005788//endoplasmic reticulum lumen;GO:0005587//collagen type IV 636 tr|B4DP80|B4DP80_HUMAN NAD(P)H-hydrate epimerase OS=Homo sapiens GN=APOA1BP PE=2 SV=1 38511 MRRGRAGPGRAGGARSASWMSRLRALLGLGLLVAGSRLPRIKSQTIACRSGPTWWGPQRLNSGGRWDSEVMASTVVKYLSQEEAQAVDQELFNEYQFSVDQLMELAGLSCATAIAKAYPPTSMSRSPPTVLVICGPGNNGGDGLVCARHLKLFGYEPTIYYPKRPNKPLFTALVTQCQKMDIPFLGEMPAEPMTIDELYELVVDAIFGFSFKGDVREPFHSILSVLKGLTVPIASIDIPSGWDVEKGNAGGIQPDLLISLTAPKKSATQFTGRYHYLGGRFVPPALEKKYQLNLPPYPDTECVYRLQ 87 13.4 1 7 7 3 3 1.76 0.92 0.881 2 2 2 - - - 1.187 0.496615545 tr|B4DP80|B4DP80_HUMAN 100 4.00E-86 gi|34783983|gb|AAH56917.1| APOA1BP protein [Homo sapiens] 100 1.00E-158 sp|Q8NCW5|NNRE_HUMAN NAD(P)H-hydrate epimerase OS=Homo sapiens GN=APOA1BP PE=1 SV=2 100 1.00E-85 Q5T3I3 Q5T3I3_HUMAN Apolipoprotein A-I binding protein OS=Homo sapiens GN=APOA1BP PE=2 SV=1 SPAC15A10.05c 204 2.00E-52 COG0062 Uncharacterized conserved protein S Function unknown ; - GO:0051289//protein homotetramerization GO:0046872//metal ion binding;GO:0016853//isomerase activity;GO:0042803//protein homodimerization activity;GO:0000166//nucleotide binding GO:0005615//extracellular space;GO:0044297//cell body;GO:0005739//mitochondrion 637 tr|B3KN06|B3KN06_HUMAN Coronin OS=Homo sapiens PE=2 SV=1 65130 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSDGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKCDLISIPKKTTDTASVQNEAKLDEILKESKSIKDTICNQDERISKLEQQMAKIAA 241 9.5 4 17 17 4 4 0.844 0.714 0.594 7 8 7 - - * 0.717333333 0.125033329 tr|B3KN06|B3KN06_HUMAN 100 0 gi|193785733|dbj|BAG51168.1| unnamed protein product [Homo sapiens] 99.58 0 sp|Q9ULV4|COR1C_HUMAN Coronin-1C OS=Homo sapiens GN=CORO1C PE=1 SV=1 100 5.00E-147 F1Q1F6 F1Q1F6_CANFA Uncharacterized protein (Fragment) OS=Canis familiaris GN=CORO1C PE=4 SV=1 all0664 68.6 2.00E-11 COG2319 FOG: WD40 repeat R General function prediction only ; K13887|1|0.0|984|hsa:23603|coronin-1C GO:0006909//phagocytosis;GO:0007165//signal transduction;GO:0030036//actin cytoskeleton organization GO:0051015//actin filament binding GO:0015629//actin cytoskeleton 638 tr|Q1JQ76|Q1JQ76_HUMAN Ribosomal protein (Fragment) OS=Homo sapiens GN=RPL10A PE=2 SV=1 33122 RTRGSVLHGNQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY 114 19.9 1 6 6 4 4 0.953 0.948 1.303 4 3 4 - - - 1.068 0.203531324 tr|Q1JQ76|Q1JQ76_HUMAN 100 1.00E-102 gi|281338435|gb|EFB14019.1| hypothetical protein PANDA_002233 [Ailuropoda melanoleuca] >gi|355561623|gb|EHH18255.1| hypothetical protein EGK_14818, partial [Macaca mulatta] 100 1.00E-103 sp|P62906|RL10A_HUMAN 60S ribosomal protein L10a OS=Homo sapiens GN=RPL10A PE=1 SV=2 100 4.00E-102 G3RV13 G3RV13_GORGO Ribosomal protein OS=Gorilla gorilla gorilla GN=ENSG00000198755 PE=3 SV=1 SPCC1183.08c 254 5.00E-68 COG0081 Ribosomal protein L1 J Translation, ribosomal structure and biogenesis ; K02865|1|1e-103|375|bta:533310|large subunit ribosomal protein L10Ae GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006414//translational elongation;GO:0006415//translational termination;GO:0009653//anatomical structure morphogenesis;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome GO:0005739//mitochondrion;GO:0022625//cytosolic large ribosomal subunit 639 tr|D6R9W4|D6R9W4_HUMAN Drebrin (Fragment) OS=Homo sapiens GN=DBN1 PE=1 SV=1 42761 MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVASASAGSCDVPSPFNHRP 65 10.4 1 4 4 3 3 --- 0.411 --- 1 2 1 - - - 0.411 - tr|D6R9W4|D6R9W4_HUMAN 100 5.00E-100 gi|119605396|gb|EAW84990.1| drebrin 1, isoform CRA_b [Homo sapiens] 99.69 2.00E-137 sp|Q16643|DREB_HUMAN Drebrin OS=Homo sapiens GN=DBN1 PE=1 SV=4 100 2.00E-47 D6RCR4 D6RCR4_HUMAN Drebrin (Fragment) OS=Homo sapiens GN=DBN1 PE=4 SV=1 - - - - - - - - GO:0032507//maintenance of protein location in cell;GO:0007015//actin filament organization;GO:0010644//cell communication by electrical coupling;GO:0010643//cell communication by chemical coupling;GO:0048168//regulation of neuronal synaptic plasticity;GO:0050773//regulation of dendrite development GO:0003779//actin binding;GO:0005522//profilin binding GO:0030425//dendrite;GO:0005921//gap junction;GO:0042641//actomyosin;GO:0005737//cytoplasm;GO:0005886//plasma membrane 640 sp|P25940|CO5A3_HUMAN Collagen alpha-3(V) chain OS=Homo sapiens GN=COL5A3 PE=1 SV=3 199166 MGNRRDLGQPRAGLCLLLAALQLLPGTQADPVDVLKALGVQGGQAGVPEGPGFCPQRTPEGDRAFRIGQASTLGIPTWELFPEGHFPENFSLLITLRGQPANQSVLLSIYDERGARQLGLALGPALGLLGDPFRPLPQQVNLTDGRWHRVAVSIDGEMVTLVADCEAQPPVLGHGPRFISIAGLTVLGTQDLGEKTFEGDIQELLISPDPQAAFQACERYLPDCDNLAPAATVAPQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQTSTDIPKTETPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLPVVEGGLEEVLASLTSLSLELEQLRRPPGTAERPGLVCHELHRNHPHLPDGEYWIDPNQGCARDSFRVFCNFTAGGETCLYPDKKFEIVKLASWSKEKPGGWYSTFRRGKKFSYVDADGSPVNVVQLNFLKLLSATARQNFTYSCQNAAAWLDEATGDYSHSARFLGTNGEELSFNQTTAATVSVPQDGCRLRKGQTKTLFEFSSSRAGFLPLWDVAATDFGQTNQKFGFELGPVCFSS 349 5.9 - 8 8 5 5 1.289 1.645 1.85 6 7 7 - * * 1.594666667 0.283866753 sp|P25940|CO5A3_HUMAN 100 7.00E-14 gi|403296321|ref|XP_003939060.1| PREDICTED: collagen alpha-3(V) chain [Saimiri boliviensis boliviensis] 100 1.00E-34 sp|P25940|CO5A3_HUMAN Collagen alpha-3(V) chain OS=Homo sapiens GN=COL5A3 PE=1 SV=3 100 5.00E-07 F7I485 F7I485_CALJA Uncharacterized protein (Fragment) OS=Callithrix jacchus GN=COL5A3 PE=4 SV=1 - - - - - - - K06236|1|0.0|955|hsa:50509|collagen, type I/II/III/V/XI, alpha GO:0030198//extracellular matrix organization - GO:0005576//extracellular region 641 tr|J3KN29|J3KN29_HUMAN 26S proteasome non-ATPase regulatory subunit 9 OS=Homo sapiens GN=PSMD9 PE=1 SV=1 28664 MSDEEARQSGGSSQAGVVTVSDVQELMRRKEEIEAQIKANYDVLESQKGIGMNEPLVDCEGYPRSDVDLYQVRTARHNIICLQNDHKAVMKQVEEALHQLHARDKEKQARDMAEAHKEAMSRKLGQSESQGPPRAFAKVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQSLHNIGSVVQHSEGPLNVTVIRRGEKHQLRLVPTRWAGKGLLGCNIIPLQR 77 5.4 1 2 2 1 1 1.253 0.619 0.692 2 2 2 - * - 0.854666667 0.346892394 tr|J3KN29|J3KN29_HUMAN 100 9.00E-113 gi|119618703|gb|EAW98297.1| proteasome (prosome, macropain) 26S subunit, non-ATPase, 9, isoform CRA_e [Homo sapiens] 99.55 2.00E-127 sp|O00233|PSMD9_HUMAN 26S proteasome non-ATPase regulatory subunit 9 OS=Homo sapiens GN=PSMD9 PE=1 SV=3 100 1.00E-82 F5H5V4 F5H5V4_HUMAN 26S proteasome non-ATPase regulatory subunit 9 (Fragment) OS=Homo sapiens GN=PSMD9 PE=4 SV=1 YIL007c 122 7.00E-28 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain O Posttranslational modification, protein turnover, chaperones ; K06693|1|2e-127|454|hsa:5715|26S proteasome non-ATPase regulatory subunit 9 GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016032//viral reproduction;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0046676//negative regulation of insulin secretion;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0000084//S phase of mitotic cell cycle;GO:0070682//proteasome regulatory particle assembly;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0045893//positive regulation of transcription, DNA-dependent;GO:0016071//mRNA metabolic process;GO:0032024//positive regulation of insulin secretion;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0003713//transcription coactivator activity;GO:0043425//bHLH transcription factor binding GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0008540//proteasome regulatory particle, base subcomplex 642 tr|Q05DB4|Q05DB4_HUMAN HEBP2 protein (Fragment) OS=Homo sapiens GN=HEBP2 PE=2 SV=1 31011 MAEPLQPDPGAAEDAAAQAVETPGWKAPEDAGPQPGSYEIRHYGPAKWVSTSVESMDWDSAIQTGFTKLNSYIQGKNEKEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQFDPPRPLESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREDGKVFDEKVYYTAGYNSPVKLLNRNNEVWLIQKNEPTKENEKKKKKKKKK 81 10.3 1 3 3 2 2 0.842 0.774 0.984 3 3 3 - - - 0.866666667 0.107150984 tr|Q05DB4|Q05DB4_HUMAN 100 3.00E-109 gi|340708005|pdb|3R8J|A Chain A, Crystal Structure Of Human Soul Protein (Orthorhombic Form) >gi|340708006|pdb|3R8J|B Chain B, Crystal Structure Of Human Soul Protein (Orthorhombic Form) >gi|340708007|pdb|3R8K|A Chain A, Crystal Structure Of Human Soul Protein (Hexagonal Form) >gi|340708008|pdb|3R8K|B Chain B, Crystal Structure Of Human Soul Protein (Hexagonal Form) >gi|340708009|pdb|3R8K|C Chain C, Crystal Structure Of Human Soul Protein (Hexagonal Form) >gi|340708010|pdb|3R8K|D Chain D, Crystal Structure Of Human Soul Protein (Hexagonal Form) 100 6.00E-111 sp|Q9Y5Z4|HEBP2_HUMAN Heme-binding protein 2 OS=Homo sapiens GN=HEBP2 PE=1 SV=1 100 2.00E-109 Q05DB4 Q05DB4_HUMAN HEBP2 protein (Fragment) OS=Homo sapiens GN=HEBP2 PE=2 SV=1 - - - - - - - - - - GO:0005739//mitochondrion 643 tr|H0Y9Q1|H0Y9Q1_HUMAN Cytosol aminopeptidase (Fragment) OS=Homo sapiens GN=LAP3 PE=1 SV=3 27509 QKKKMAVSAKLYGSGDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWIEEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMDLMRADMGGAATICSAIVSAAKLNLPINIIGAMDVALGSGATGVFTNSSWLWNKLFEASIETGDRVWRMPLFEHYT 92 11.5 2 3 3 2 2 0.76 1.452 0.852 3 3 3 - - - 1.021333333 0.37579427 tr|H0Y9Q1|H0Y9Q1_HUMAN 92.68 2.00E-85 gi|431897201|gb|ELK06463.1| Cytosol aminopeptidase [Pteropus alecto] 70.8 3.00E-101 sp|P28838|AMPL_HUMAN Cytosol aminopeptidase OS=Homo sapiens GN=LAP3 PE=1 SV=3 100 6.00E-119 H0Y9Q1 H0Y9Q1_HUMAN Cytosol aminopeptidase (Fragment) OS=Homo sapiens GN=LAP3 PE=4 SV=1 SPAC13A11.05 139 4.00E-33 COG0260 Leucyl aminopeptidase E Amino acid transport and metabolism ; K11142|1|3e-101|367|hsa:51056|cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5] GO:0006508//proteolysis GO:0030145//manganese ion binding;GO:0008235//metalloexopeptidase activity;GO:0004177//aminopeptidase activity;GO:0000287//magnesium ion binding;GO:0008270//zinc ion binding GO:0005737//cytoplasm;GO:0005730//nucleolus 644 sp|Q9UKU9|ANGL2_HUMAN Angiopoietin-related protein 2 OS=Homo sapiens GN=ANGPTL2 PE=2 SV=1 >tr|A0A024R868|A0A024R868_HUMAN Angiopoietin-like 2, isoform CRA_a OS=Homo sapiens GN=ANGPTL2 PE=4 SV=1 64883 MRPLCVTCWWLGLLAAMGAVAGQEDGFEGTEEGSPREFIYLNRYKRAGESQDKCTYTFIVPQQRVTGAICVNSKEPEVLLENRVHKQELELLNNELLKQKRQIETLQQLVEVDGGIVSEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKDLEHKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPPPAAPPRVYQPPTYNRIINQISTNEIQSDQNLKVLPPPLPTMPTLTSLPSSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPNPNTFH 92 6.7 - 4 4 3 3 0.95 2.23 0.997 3 3 3 - - - 1.392333333 0.725821144 sp|Q9UKU9|ANGL2_HUMAN 100 0 gi|6912236|ref|NP_036230.1| angiopoietin-related protein 2 precursor [Homo sapiens] >gi|13626119|sp|Q9UKU9.1|ANGL2_HUMAN RecName: Full=Angiopoietin-related protein 2; AltName: Full=Angiopoietin-like protein 2; Flags: Precursor >gi|5901651|gb|AAD55357.1|AF125175_1 angiopoietin-related protein-2 [Homo sapiens] >gi|15214489|gb|AAH12368.1| Angiopoietin-like 2 [Homo sapiens] >gi|37181668|gb|AAQ88641.1| NL1 [Homo sapiens] >gi|119608055|gb|EAW87649.1| angiopoietin-like 2, isoform CRA_a [Homo sapiens] >gi|119608058|gb|EAW87652.1| angiopoietin-like 2, isoform CRA_a [Homo sapiens] 100 0 sp|Q9UKU9|ANGL2_HUMAN Angiopoietin-related protein 2 OS=Homo sapiens GN=ANGPTL2 PE=2 SV=1 100 2.00E-112 Q8NCH7 Q8NCH7_HUMAN Angiopoietin-like 2 OS=Homo sapiens GN=ANGPTL2 PE=2 SV=1 - - - - - - - K03903|1|4e-51|202|tgu:100229261|fibrinogen alpha chain!K10104|3|5e-50|199|acs:100552831|ficolin GO:0007165//signal transduction;GO:0007275//multicellular organismal development GO:0005102//receptor binding GO:0005615//extracellular space 645 sp|Q92626|PXDN_HUMAN Peroxidasin homolog OS=Homo sapiens GN=PXDN PE=1 SV=2 181786 MAKRSRGPGRRCLLALVLFCAWGTLAVVAQKPGAGCPSRCLCFRTTVRCMHLLLEAVPAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVATSIVEAIATVDRAINSTRTHLFDSRPRSPNDLLALFRYPRDPYTVEQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYHYNDLVSPQYLNLIANLSGCTAHRRVNNCSDMCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMPRLVSTTLIGTETVTPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSNVCSNDPPCFSVMIPPNDSRARSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTEHEARSIRDLASHRGLLRQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKILGEVGMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRLDENFQPIAQDHLPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLFPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPGVFSPAQLTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQDCCEDCRTRGQFNAFSYHFRGRRSLEFSYQEDKPTKKTRPRKIPSVGRQGEHLSNSTSAFSTRSDASGTNDFREFVLEMQKTITDLRTQIKKLESRLSTTECVDAGGESHANNTKWKKDACTICECKDGQVTCFVEACPPATCAVPVNIPGACCPVCLQKRAEEKP 388 9.1 - 28 28 12 12 1.547 1.212 1.108 14 14 12 * * - 1.289 0.229405754 sp|Q92626|PXDN_HUMAN 100 0 gi|6273399|gb|AAF06354.1|AF200348_1 melanoma-associated antigen MG50 [Homo sapiens] >gi|1504040|dbj|BAA13219.1| KIAA0230 [Homo sapiens] 100 0 sp|Q92626|PXDN_HUMAN Peroxidasin homolog OS=Homo sapiens GN=PXDN PE=1 SV=2 100 0 H7C1W1 H7C1W1_HUMAN Peroxidasin homolog (Fragment) OS=Homo sapiens GN=PXDN PE=4 SV=1 YKL193c 70.9 2.00E-11 COG4886 Leucine-rich repeat (LRR) protein S Function unknown ; K00431|1|2e-172|607|bfo:BRAFLDRAFT_67515|thyroid peroxidase [EC:1.11.1.8] GO:0042744//hydrogen peroxide catabolic process;GO:0055114//oxidation-reduction process;GO:0006955//immune response;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0030198//extracellular matrix organization GO:0046872//metal ion binding;GO:0004601//peroxidase activity;GO:0005152//interleukin-1 receptor antagonist activity;GO:0020037//heme binding;GO:0005201//extracellular matrix structural constituent GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0005783//endoplasmic reticulum 646 tr|A0A0A0MSW4|A0A0A0MSW4_HUMAN Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens GN=PITPNB PE=4 SV=1 40364 MVLIKEFRVVLPCSVQEYQVGQLYSVAEASKNETGGGEGIEVLKNEPYEKDGEKGQYTHKIYHLKSKVPAFVRMIAPEGSLVFHEKAWNAYPYCRTILQNEYMKDDFFIKIETWHKPDLGTLENVHGLDPNTWKTVEIVHIDIADRSQVEPADYKADEDPALFQSVKTKRGPLGPNWKKELANSPDCPQMCAYKLVTIKFKWWGLQSKVENFIQKQEKRIFTNFHRQLFCWIDKWIDLTMEDIRRMEDETQKELETMRKRGSVRGTSAADV 78 15.1 2 8 7 4 3 1.249 1.516 1.39 2 2 2 - - - 1.385 0.133570206 tr|A0A0A0MSW4|A0A0A0MSW4_HUMAN 99.26 1.00E-159 gi|6912594|ref|NP_036531.1| phosphatidylinositol transfer protein beta isoform [Homo sapiens] >gi|388453391|ref|NP_001253258.1| phosphatidylinositol transfer protein beta isoform [Macaca mulatta] >gi|1346772|sp|P48739.2|PIPNB_HUMAN RecName: Full=Phosphatidylinositol transfer protein beta isoform; Short=PI-TP-beta; Short=PtdIns transfer protein beta; Short=PtdInsTP beta >gi|1060905|dbj|BAA06277.1| phosphatidylinositol transfer protein [Homo sapiens] >gi|17511691|gb|AAH18704.1| Phosphatidylinositol transfer protein, beta [Homo sapiens] >gi|47678613|emb|CAG30427.1| PITPNB [Homo sapiens] 99.26 1.00E-160 sp|P48739|PIPNB_HUMAN Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens GN=PITPNB PE=1 SV=2 100 3.00E-160 C9JW90 C9JW90_HUMAN Uncharacterized protein OS=Homo sapiens GN=PITPNB PE=4 SV=1 - - - - - - - K01106|1|9e-124|442|gga:771549|inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56]!K09441|2|9e-12|70.9|spu:591116|GA-binding protein transcription factor, alpha GO:0046474//glycerophospholipid biosynthetic process;GO:0001701//in utero embryonic development;GO:0044281//small molecule metabolic process;GO:0015914//phospholipid transport GO:0008526//phosphatidylinositol transporter activity;GO:0005543//phospholipid binding GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane 647 tr|H3BTH8|H3BTH8_HUMAN Hyaluronan and proteoglycan link protein 3 OS=Homo sapiens GN=HAPLN3 PE=4 SV=1 52423 MRKWRHREVNLPEVTQQDAVCPAPIPSPGLSAQTGLQKIWGTIHCQVCPGAPAWPGSPWHEEMGLLLLVPLLLLPGSYGLPFYNGFYYSNSANDQNLGNGHGKDLLNGVKLVVETPEETLFTYQGASVILPCRYRYEPALVSPRRVRVKWWKLSENGAPEKDVLVAIGLRHRSFGDYQGRVHLRQDKEHDVSLEIQDLRLEDYGRYRCEVIDGLEDESGLVELELRGVVFPYQSPNGRYQFNFHEGQQVCAEQAAVVASFEQLFRAWEEGLDWCNAGWLQDATVQYPIMLPRQPCGGPGLAPGVRSYGPRHRRLHRYDVFCFATALKGRVYYLEHPEKLTLTEAREACQEDDATIAKVGQLFAAWKFHGLDRCDAGWLADGSVRYPVVHPHPNCGPPEPGVRSFGFPDPQSRLYGVYCYRQH 304 4.7 2 34 34 2 2 1.148 0.635 0.964 23 21 23 - * - 0.915666667 0.259892927 tr|H3BTH8|H3BTH8_HUMAN 100 0 gi|30102948|ref|NP_839946.1| hyaluronan and proteoglycan link protein 3 precursor [Homo sapiens] >gi|47605734|sp|Q96S86.1|HPLN3_HUMAN RecName: Full=Hyaluronan and proteoglycan link protein 3; Flags: Precursor >gi|14585875|gb|AAK67639.1| proteoglycan link protein [Homo sapiens] >gi|30349293|gb|AAP22051.1| hyaluronan and proteoglycan link protein 3 [Homo sapiens] >gi|37182123|gb|AAQ88864.1| GLLL238 [Homo sapiens] >gi|38383001|gb|AAH62320.1| HAPLN3 protein [Homo sapiens] >gi|119622427|gb|EAX02022.1| hyaluronan and proteoglycan link protein 3, isoform CRA_a [Homo sapiens] >gi|119622429|gb|EAX02024.1| hyaluronan and proteoglycan link protein 3, isoform CRA_a [Homo sapiens] 100 0 sp|Q96S86|HPLN3_HUMAN Hyaluronan and proteoglycan link protein 3 OS=Homo sapiens GN=HAPLN3 PE=2 SV=1 100 5.00E-78 H3BRY4 H3BRY4_HUMAN Hyaluronan and proteoglycan link protein 3 OS=Homo sapiens GN=HAPLN3 PE=4 SV=1 - - - - - - - K06852|1|0.0|677|hsa:145864|hyaluronan and proteoglycan link protein 3 GO:0007155//cell adhesion GO:0005540//hyaluronic acid binding GO:0005578//proteinaceous extracellular matrix 648 tr|K7EQA1|K7EQA1_HUMAN Programmed cell death protein 5 OS=Homo sapiens GN=PDCD5 PE=1 SV=1 13040 MRNSILAQVLDQSARARLSNLALVKPEKTKAVENYLIQMARYGQLSEKVSEQGLIEILKKVSQQTEKTTTVKFNRRKVMDSDEDDDY 88 12.6 1 6 6 1 1 1.046 1.165 1.513 5 5 4 - - - 1.241333333 0.242677427 tr|K7EQA1|K7EQA1_HUMAN 100 3.00E-43 gi|355767362|gb|EHH62604.1| hypothetical protein EGM_20995, partial [Macaca fascicularis] 100 3.00E-44 sp|Q5RBT0|PDCD5_PONAB Programmed cell death protein 5 OS=Pongo abelii GN=PDCD5 PE=2 SV=3 100 1.00E-42 H2QFY9 H2QFY9_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000105185 PE=4 SV=1 SPAC23C4.09c 72.8 1.00E-13 COG2118 DNA-binding protein R General function prediction only ; K06875|1|2e-44|176|mcc:702277|programmed cell death protein 5 GO:0006917//induction of apoptosis GO:0003677//DNA binding GO:0005737//cytoplasm;GO:0005634//nucleus 649 sp|Q8NCC3|PAG15_HUMAN Group XV phospholipase A2 OS=Homo sapiens GN=PLA2G15 PE=1 SV=2 52085 MGLHLRPYRVGLLPDGLLFLLLLLMLLADPALPAGRHPPVVLVPGDLGNQLEAKLDKPTVVHYLCSKKTESYFTIWLNLELLLPVIIDCWIDNIRLVYNKTSRATQFPDGVDVRVPGFGKTFSLEFLDPSKSSVGSYFHTMVESLVGWGYTRGEDVRGAPYDWRRAPNENGPYFLALREMIEEMYQLYGGPVVLVAHSMGNMYTLYFLQRQPQAWKDKYIRAFVSLGAPWGGVAKTLRVLASGDNNRIPVIGPLKIREQQRSAVSTSWLLPYNYTWSPEKVFVQTPTINYTLRDYRKFFQDIGFEDGWLMRQDTEGLVEATMPPGVQLHCLYGTGVPTPDSFYYESFPDRDPKICFGDGDGTVNLKSALQCQAWQSRQEHQVLLQELPGSEHIEMLANATTLAYLKRVLLGP 266 18.2 - 17 17 6 6 0.787 0.526 0.647 7 7 7 - - - 0.653333333 0.130615211 sp|Q8NCC3|PAG15_HUMAN 100 0 gi|6912484|ref|NP_036452.1| group XV phospholipase A2 precursor [Homo sapiens] >gi|44888104|sp|Q8NCC3.2|PAG15_HUMAN RecName: Full=Group XV phospholipase A2; AltName: Full=1-O-acylceramide synthase; Short=ACS; AltName: Full=LCAT-like lysophospholipase; Short=LLPL; AltName: Full=Lysophospholipase 3; AltName: Full=Lysosomal phospholipase A2; Short=LPLA2; Flags: Precursor >gi|4589720|dbj|BAA76877.1| LCAT-like lysophospholipase (LLPL) [Homo sapiens] >gi|37181975|gb|AAQ88791.1| LLPL [Homo sapiens] >gi|38566286|gb|AAH62605.1| Phospholipase A2, group XV [Homo sapiens] >gi|119603623|gb|EAW83217.1| lysophospholipase 3 (lysosomal phospholipase A2), isoform CRA_a [Homo sapiens] 100 0 sp|Q8NCC3|PAG15_HUMAN Group XV phospholipase A2 OS=Homo sapiens GN=PLA2G15 PE=1 SV=2 100 2.00E-96 B4DPU0 B4DPU0_HUMAN Group XV phospholipase A2 OS=Homo sapiens GN=PLA2G15 PE=2 SV=1 - - - - - - - K06129|1|0.0|793|hsa:23659|lysophospholipase III [EC:3.1.1.5] GO:0046470//phosphatidylcholine metabolic process;GO:0009062//fatty acid catabolic process;GO:0006672//ceramide metabolic process GO:0047499//calcium-independent phospholipase A2 activity;GO:0005543//phospholipid binding;GO:0008374//O-acyltransferase activity;GO:0004622//lysophospholipase activity GO:0005764//lysosome;GO:0005739//mitochondrion;GO:0005576//extracellular region 650 sp|Q7L9L4|MOB1B_HUMAN MOB kinase activator 1B OS=Homo sapiens GN=MOB1B PE=1 SV=3 30721 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR 58 5.1 1 2 2 1 1 0.977 0.885 0.652 2 2 2 - - - 0.838 0.167520148 sp|Q7L9L4|MOB1B_HUMAN 100 5.00E-124 gi|301768280|ref|XP_002919564.1| PREDICTED: mps one binder kinase activator-like 1A-like [Ailuropoda melanoleuca] 100 1.00E-127 sp|Q8BPB0|MOB1B_MOUSE MOB kinase activator 1B OS=Mus musculus GN=Mob1b PE=1 SV=3 100 1.00E-123 H2RCF2 H2RCF2_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000173542 PE=4 SV=1 - - - - - - - K06685|1|1e-127|455|ssc:100517174|maintenance of ploidy protein MOB1 (MPS1 binder 1) GO:0046777//protein autophosphorylation;GO:0042327//positive regulation of phosphorylation;GO:0035329//hippo signaling cascade;GO:0043085//positive regulation of catalytic activity GO:0019900//kinase binding;GO:0046872//metal ion binding;GO:0016301//kinase activity;GO:0019209//kinase activator activity GO:0005829//cytosol;GO:0005634//nucleus 651 sp|Q8IVF2|AHNK2_HUMAN Protein AHNAK2 OS=Homo sapiens GN=AHNAK2 PE=1 SV=2 799602 MCDCFHMVLPTWPGTPGSVSGRQLQPGEPGAETEDDHSVTEGPADEGIRPRPQGSSPVYEYTTEAADFGLQEDAPGRQGSAGRRRSWWKRDSGDSRTFFRMSRPEAVQEATEVTLKTEVEAGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLSTTVFFENIKYEDALKILQYSEPYKVQFKIRRQLPAPQDEEWASSDAQHGPQGKEKEDTDVADGCRETPTKTLEGDGDQERLISKPRVGRGRQSQRERLSWPKFQSIKSKRGPGPQRSHSSSEAYEPRDAHDVSPTSTDTEAQLTVERQEQKAGPGSQRRRKFLNLRFRTGSGQGPSSTGQPGRGFQSGVGRAGVLEELGPWGDSLEETGAATGSRREERAEQDREVMPAQSMPLPTELGDPRLCEGTPQEGGLRAARLHGKTLEGQAQETAVAQRKPRAQPTPGMSREGEGEGLQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEGAGWMPGREPTTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQILTEKEVATKDSKFKMPKFKMPLFGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKTTDLSVQTPSADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDLSAPKVEADMSLPSMQGDLKTTDLSIQPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSEPKVEADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKGPKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEAEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVDLKGPQTDVKGAKLDLKGPKAEVTAPDVEVSLPSMEVDVQAQKAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSIEASVDVPAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKTDVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSAPKVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQLDVKGPKLDLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVSVDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLPSMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIKGPKLDLKGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKVPKAEVTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSMEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVHVSAPKVEADVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADVMTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSIEASLDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKMEADMSIPSMQGDLKTTDLRIQAPSADLEVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVDLKGPQVDVKGPKLDLKGPKAEVMAPDVEVSLPSVETDVQAPGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEWSSKKVSMSSSEIEGNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEVGMDSKFKKLHFKVPKVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPHFESSILSPCEDVTLTKYQVTVPRAALAPELALEIPSGSQADIPLPKTECSTDLQPPEGVPTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQGPEELVASLQTSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVDPECSVEDSKLSLVLDKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASKSGVSLPQRDVDPSLSSATAGGSFQDTEKASSDGGRGGLGATASATGSEGVNLHRPQVHIPSLGFAKPDLRSSKAKVEVSQPEADLPLPKHDLSTEGDSRGCGLGDVPVSQPCGEGIAPTPEDPLQPSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDRGGAGKLEVAQTQAPAATGGEAAAKVKEFLVSGSNVEAAMSLQLPEADAEVTASESKSSTDILRCDLDSTGLKLHLSTAGMTGDELSTSEVRIHPSKGPLPFQMPGMRLPETQVLPGEIDETPLSKPGHDLASMEDKTEKWSSQPEGPLKLKASSTDMPSQISVVNVDQLWEDSVLTVKFPKLMVPRFSFPAPSSEDDVFIPTVREVQCPEANIDTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEAPPISKVRVHIQGAQVESQEVTIHSIVTPEFVDLSVPRTFSTQIVRESEIPTSEIQTPSYGFSLLKVKIPEPHTQARVYTTMTQHSRTQEGTEEAPIQATPGVDSISGDLQPDTGEPFEMISSSVNVLGQQTLTFEVPSGHQLADSCSDEEPAEILEFPPDDSQEATTPLADEGRAPKDKPESKKSGLLWFWLPNIGFSSSVDETGVDSKNDVQRSAPIQTQPEARPEAELPKKQEKAGWFRFPKLGFSSSPTKKSKSTEDGAELEEQKLQEETITFFDARESFSPEEKEEGELIGPVGTGLDSRVMVTSAARTELILPEQDRKADDESKGSGLGPNEG 346 4.5 - 23 23 19 19 0.718 0.569 0.599 12 14 14 * - - 0.628666667 0.078805668 sp|Q8IVF2|AHNK2_HUMAN 100 0 gi|60551093|gb|AAH90889.1| AHNAK2 protein [Homo sapiens] 100 0 sp|Q8IVF2|AHNK2_HUMAN Protein AHNAK2 OS=Homo sapiens GN=AHNAK2 PE=1 SV=2 95.29 0 H2NMF1 H2NMF1_PONAB Uncharacterized protein OS=Pongo abelii GN=LOC100447005 PE=4 SV=1 - - - - - - - - - - GO:0005634//nucleus 652 tr|B2R6Q2|B2R6Q2_HUMAN Alkaline phosphatase OS=Homo sapiens PE=2 SV=1 66103 MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRHKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDEKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF 83 4 3 3 3 2 2 1.286 2.351 1.92 2 2 2 - - * 1.852333333 0.535714787 tr|B2R6Q2|B2R6Q2_HUMAN 100 0 gi|189069211|dbj|BAG35549.1| unnamed protein product [Homo sapiens] 99.6 0 sp|P05186|PPBT_HUMAN Alkaline phosphatase, tissue-nonspecific isozyme OS=Homo sapiens GN=ALPL PE=1 SV=4 100 0 B2R6Q2 B2R6Q2_HUMAN Alkaline phosphatase OS=Homo sapiens PE=2 SV=1 XF0657 301 2.00E-81 COG1785 Alkaline phosphatase P Inorganic ion transport and metabolism ; K01077|1|0.0|1040|hsa:249|alkaline phosphatase [EC:3.1.3.1] GO:0046677//response to antibiotic;GO:0071407//cellular response to organic cyclic compound;GO:0016311//dephosphorylation;GO:0001501//skeletal system development;GO:0051384//response to glucocorticoid stimulus;GO:0071529//cementum mineralization;GO:0033280//response to vitamin D;GO:0003006//developmental process involved in reproduction;GO:0032496//response to lipopolysaccharide GO:0004035//alkaline phosphatase activity;GO:0046872//metal ion binding;GO:0016462//pyrophosphatase activity GO:0016021//integral to membrane;GO:0005615//extracellular space;GO:0031225//anchored to membrane;GO:0005886//plasma membrane 653 tr|I1VZV6|I1VZV6_HUMAN Hemoglobin alpha 1 OS=Homo sapiens GN=HBA1 PE=3 SV=1 18977 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVHDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR 72 16.9 6 10 10 2 2 0.87 1.03 0.643 6 6 6 - - * 0.847666667 0.194464221 tr|I1VZV6|I1VZV6_HUMAN 100 2.00E-76 gi|385275336|gb|AFI57164.1| hemoglobin alpha 1 [Homo sapiens] 99.3 2.00E-76 sp|P69906|HBA_PANPA Hemoglobin subunit alpha OS=Pan paniscus GN=HBA1 PE=1 SV=2 99.3 9.00E-75 Q5R9M5 Q5R9M5_PONAB Putative uncharacterized protein DKFZp468J1717 OS=Pongo abelii GN=DKFZp468J1717 PE=2 SV=1 - - - - - - - K13822|1|2e-76|283|pon:100172834|hemoglobin subunit alpha GO:0042744//hydrogen peroxide catabolic process;GO:0051291//protein heterooligomerization;GO:0010942//positive regulation of cell death;GO:0015701//bicarbonate transport;GO:0015671//oxygen transport;GO:0044281//small molecule metabolic process GO:0004601//peroxidase activity;GO:0005344//oxygen transporter activity;GO:0019825//oxygen binding;GO:0031720//haptoglobin binding;GO:0020037//heme binding;GO:0005506//iron ion binding GO:0022627//cytosolic small ribosomal subunit;GO:0031838//haptoglobin-hemoglobin complex;GO:0005833//hemoglobin complex 654 sp|Q09666|AHNK_HUMAN Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens GN=AHNAK PE=1 SV=2 881095 MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATIYFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLSGDDEEYQRIYTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSPEFKIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGPSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKVGIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAEASSPKGKFSLFKSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGKHGKLKFGTFGGLGSKSKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPEVELSVSTKKE 4307 17.4 - 189 140 71 59 0.77 0.797 0.744 111 112 108 * * * 0.770333333 0.026501572 sp|Q09666|AHNK_HUMAN 100 0 gi|61743954|ref|NP_001611.1| neuroblast differentiation-associated protein AHNAK isoform 1 [Homo sapiens] >gi|160332335|sp|Q09666.2|AHNK_HUMAN RecName: Full=Neuroblast differentiation-associated protein AHNAK; AltName: Full=Desmoyokin 100 0 sp|Q09666|AHNK_HUMAN Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens GN=AHNAK PE=1 SV=2 100 1.00E-45 E9PLZ1 E9PLZ1_HUMAN Neuroblast differentiation-associated protein AHNAK (Fragment) OS=Homo sapiens GN=AHNAK PE=4 SV=1 - - - - - - - - GO:0007399//nervous system development GO:0005515//protein binding GO:0005634//nucleus 655 tr|I1SRC5|I1SRC5_HUMAN UBE2L3/KRAS fusion protein OS=Homo sapiens PE=2 SV=1 43183 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQGLLKMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCIIM 271 11.1 2 10 10 2 2 0.858 0.472 0.89 8 8 7 - - - 0.74 0.232645653 tr|I1SRC5|I1SRC5_HUMAN 100 7.00E-101 gi|395744076|ref|XP_003778042.1| PREDICTED: GTPase KRas-like isoform 3 [Pongo abelii] >gi|397517431|ref|XP_003828914.1| PREDICTED: GTPase KRas isoform 3 [Pan paniscus] >gi|441669759|ref|XP_004092140.1| PREDICTED: GTPase KRas [Nomascus leucogenys] 100 4.00E-46 sp|P68037|UB2L3_MOUSE Ubiquitin-conjugating enzyme E2 L3 OS=Mus musculus GN=Ube2l3 PE=2 SV=1 100 3.00E-100 H0VHH8 H0VHH8_CAVPO Uncharacterized protein OS=Cavia porcellus GN=KRAS PE=4 SV=1 SPAC17H9.09c 204 2.00E-52 COG1100 GTPase SAR1 and related small G proteins R General function prediction only ; K07827|1|3e-101|368|cfa:403871|GTPase KRas!K02833|4|1e-87|323|mdo:100032921|GTPase HRas GO:0043524//negative regulation of neuron apoptotic process;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0008284//positive regulation of cell proliferation;GO:0035022//positive regulation of Rac protein signal transduction;GO:0007411//axon guidance;GO:0000186//activation of MAPKK activity;GO:0051384//response to glucocorticoid stimulus;GO:0043406//positive regulation of MAP kinase activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007596//blood coagulation;GO:0019221//cytokine-mediated signaling pathway;GO:0008542//visual learning;GO:0050900//leukocyte migration;GO:0035176//social behavior;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0051146//striated muscle cell differentiation;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0010628//positive regulation of gene expression;GO:0051385//response to mineralocorticoid stimulus;GO:0030036//actin cytoskeleton organization;GO:0006184//GTP catabolic process;GO:0000165//MAPK cascade;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0008286//insulin receptor signaling pathway GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0019002//GMP binding;GO:0030275//LRR domain binding;GO:0003924//GTPase activity GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0005739//mitochondrion 656 sp|P02461|CO3A1_HUMAN Collagen alpha-1(III) chain OS=Homo sapiens GN=COL3A1 PE=1 SV=4 158898 MMSFVQKGSWLLLALLHPTIILAQQEAVEGGCSHLGQSYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDEPMDFKINTDEIMTSLKSVNGQIESLISPDGSRKNPARNCRDLKFCHPELKSGEYWVDPNQGCKLDAIKVFCNMETGETCISANPLNVPRKHWWTDSSAEKKHVWFGESMDGGFQFSYGNPELPEDVLDVHLAFLRLLSSRASQNITYHCKNSIAYMDQASGNVKKALKLMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYRTRKAVRLPIVDIAPYDIGGPDQEFGVDVGPVCFL 2580 26.3 - 90 90 22 22 1.573 1.953 1.866 72 72 70 * * * 1.797333333 0.199088757 sp|P02461|CO3A1_HUMAN 100 9.00E-55 gi|124056490|sp|P02461.4|CO3A1_HUMAN RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor >gi|270048012|gb|ACZ58371.1| collagen, type III, alpha 1 [Homo sapiens] 100 2.00E-09 sp|P02461|CO3A1_HUMAN Collagen alpha-1(III) chain OS=Homo sapiens GN=COL3A1 PE=1 SV=4 100 3.00E-22 G3RK87 G3RK87_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=COL3A1 PE=4 SV=1 - - - - - - - K06236|1|2e-142|507|hsa:1281|collagen, type I/II/III/V/XI, alpha GO:0007411//axon guidance;GO:0030168//platelet activation;GO:0007160//cell-matrix adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007507//heart development;GO:0050777//negative regulation of immune response;GO:0007229//integrin-mediated signaling pathway;GO:0034097//response to cytokine stimulus;GO:0032964//collagen biosynthetic process;GO:0018149//peptide cross-linking;GO:0030199//collagen fibril organization;GO:0043588//skin development;GO:0009314//response to radiation;GO:0043206//extracellular fibril organization GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0048407//platelet-derived growth factor binding GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005586//collagen type III 657 sp|P30041|PRDX6_HUMAN Peroxiredoxin-6 OS=Homo sapiens GN=PRDX6 PE=1 SV=3 >tr|V9HWC7|V9HWC7_HUMAN Epididymis secretory sperm binding protein Li 128m OS=Homo sapiens GN=HEL-S-128m PE=2 SV=1 30913 MPGGLLLGDVAPNFEANTTVGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIALSIDSVEDHLAWSKDINAYNCEEPTEKLPFPIIDDRNRELAILLGMLDPAEKDEKGMPVTARVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATPVDWKDGDSVMVLPTIPEEEAKKLFPKGVFTKELPSGKKYLRYTPQP 306 20.5 - 15 15 5 5 1.112 1.103 0.779 10 10 8 - - * 0.998 0.189712941 sp|P30041|PRDX6_HUMAN 100 5.00E-127 gi|4758638|ref|NP_004896.1| peroxiredoxin-6 [Homo sapiens] >gi|1718024|sp|P30041.3|PRDX6_HUMAN RecName: Full=Peroxiredoxin-6; AltName: Full=1-Cys peroxiredoxin; Short=1-Cys PRX; AltName: Full=24 kDa protein; AltName: Full=Acidic calcium-independent phospholipase A2; Short=aiPLA2; AltName: Full=Antioxidant protein 2; AltName: Full=Liver 2D page spot 40; AltName: Full=Non-selenium glutathione peroxidase; Short=NSGPx; AltName: Full=Red blood cells page spot 12 >gi|285949|dbj|BAA03496.1| KIAA0106 [Homo sapiens] >gi|23274223|gb|AAH35857.1| Peroxiredoxin 6 [Homo sapiens] >gi|31657160|gb|AAH53550.1| Peroxiredoxin 6 [Homo sapiens] >gi|77744395|gb|ABB02185.1| peroxiredoxin 6 [Homo sapiens] >gi|119611350|gb|EAW90944.1| peroxiredoxin 6, isoform CRA_a [Homo sapiens] >gi|119611351|gb|EAW90945.1| peroxiredoxin 6, isoform CRA_a [Homo sapiens] 100 7.00E-128 sp|P30041|PRDX6_HUMAN Peroxiredoxin-6 OS=Homo sapiens GN=PRDX6 PE=1 SV=3 100 1.00E-106 H2N4N8 H2N4N8_PONAB Peroxiredoxin-6 (Fragment) OS=Pongo abelii GN=PRDX6 PE=4 SV=1 PA3450 231 9.00E-61 COG0450 Peroxiredoxin O Posttranslational modification, protein turnover, chaperones ; K11188|1|7e-128|456|ptr:738041|peroxiredoxin 6, 1-Cys peroxiredoxin [EC:1.11.1.7 1.11.1.15 3.1.1.-] GO:0042744//hydrogen peroxide catabolic process;GO:0055114//oxidation-reduction process;GO:0009395//phospholipid catabolic process;GO:0032060//bleb assembly GO:0004602//glutathione peroxidase activity;GO:0005515//protein binding;GO:0004623//phospholipase A2 activity;GO:0051920//peroxiredoxin activity GO:0005829//cytosol;GO:0005764//lysosome;GO:0005739//mitochondrion;GO:0016023//cytoplasmic membrane-bounded vesicle 658 tr|B4DHR1|B4DHR1_HUMAN cDNA FLJ53009, highly similar to Calreticulin OS=Homo sapiens PE=2 SV=1 31440 MLLSVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDEEKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDP 512 31.6 2 24 24 6 6 1.135 0.684 1.248 17 19 18 - - * 1.022333333 0.298402971 tr|B4DHR1|B4DHR1_HUMAN 100 2.00E-112 gi|355755517|gb|EHH59264.1| CRP55, partial [Macaca fascicularis] 99.52 3.00E-121 sp|Q4VIT5|CALR_CHLAE Calreticulin OS=Chlorocebus aethiops GN=CALR PE=2 SV=1 100 7.00E-121 B4DHR1 B4DHR1_HUMAN cDNA FLJ53009, highly similar to Calreticulin OS=Homo sapiens PE=2 SV=1 - - - - - - - K08057|1|3e-121|433|mcc:716910|calreticulin GO:0055007//cardiac muscle cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0008284//positive regulation of cell proliferation;GO:0043687//post-translational protein modification;GO:0030866//cortical actin cytoskeleton organization;GO:0007283//spermatogenesis;GO:0017148//negative regulation of translation;GO:0033574//response to testosterone stimulus;GO:0045740//positive regulation of DNA replication;GO:0002502//peptide antigen assembly with MHC class I protein complex;GO:0042981//regulation of apoptotic process;GO:0006611//protein export from nucleus;GO:0042921//glucocorticoid receptor signaling pathway;GO:0051208//sequestering of calcium ion;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007050//cell cycle arrest;GO:0071285//cellular response to lithium ion;GO:0022417//protein maturation by protein folding;GO:0040020//regulation of meiosis;GO:0050821//protein stabilization;GO:0050766//positive regulation of phagocytosis;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0045787//positive regulation of cell cycle;GO:0033144//negative regulation of intracellular steroid hormone receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0018279//protein N-linked glycosylation via asparagine;GO:0032355//response to estradiol stimulus;GO:0042493//response to drug;GO:0090398//cellular senescence;GO:0034504//protein localization to nucleus GO:0051087//chaperone binding;GO:0005506//iron ion binding;GO:0051082//unfolded protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042562//hormone binding;GO:0044183//protein binding involved in protein folding;GO:0030246//carbohydrate binding;GO:0001849//complement component C1q binding;GO:0005178//integrin binding;GO:0003729//mRNA binding;GO:0050681//androgen receptor binding;GO:0042277//peptide binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0005509//calcium ion binding GO:0005829//cytosol;GO:0005615//extracellular space;GO:0005844//polysome;GO:0005578//proteinaceous extracellular matrix;GO:0001669//acrosomal vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0042824//MHC class I peptide loading complex;GO:0005794//Golgi apparatus;GO:0009897//external side of plasma membrane;GO:0071556//integral to lumenal side of endoplasmic reticulum membrane;GO:0033018//sarcoplasmic reticulum lumen;GO:0005634//nucleus 659 tr|D3YTG3|D3YTG3_HUMAN Target of Nesh-SH3 OS=Homo sapiens GN=ABI3BP PE=4 SV=1 237869 MRGGKCNMLSSLGCLLLCGSITLALGNAQKLPKGKRPNLKVHINTTSDSILLKFLRPSPNVKLEGLLLGYGSNVSPNQYFPLPAEGKFTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTLPSHCPNDRFYTIRYREKDKEKKWIFQICPATETIVENLKPNTVYEFGVKDNVEGGIWSKIFNHKTVVGSKKVNGKIQSTYDQDHTVPAYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLVLSKRTPETLQTILIPQFELPLSTLAPKSLPEFPEAKTPFPFEKPRGTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVPKSKPALEPATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTKSVSEPVPFETEAPSMTIVPTTDIEPVTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDFGPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIFEPVSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPSPEVPQTKLVPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPKTTSSPEVPQNKSVSVTGFEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESQPVSDVLESVTLSTESPKETIAPAKTDYVYPTAKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPVLNRTTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLTSDQLPIKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW 758 8.7 1 51 51 13 13 0.409 0.222 0.283 31 30 31 * * * 0.304666667 0.095364214 tr|D3YTG3|D3YTG3_HUMAN 100 0 gi|119600216|gb|EAW79810.1| ABI gene family, member 3 (NESH) binding protein, isoform CRA_g [Homo sapiens] 94.8 0 sp|Q7Z7G0|TARSH_HUMAN Target of Nesh-SH3 OS=Homo sapiens GN=ABI3BP PE=1 SV=1 100 2.00E-67 H7C4S3 H7C4S3_HUMAN Target of Nesh-SH3 (Fragment) OS=Homo sapiens GN=ABI3BP PE=4 SV=1 - - - - - - - K06759|1|8e-06|54.7|acs:100557818|contactin 1 - - GO:0031012//extracellular matrix;GO:0005615//extracellular space 660 tr|H3BR27|H3BR27_HUMAN RNA-binding motif protein, X chromosome, N-terminally processed OS=Homo sapiens GN=RBMX PE=1 SV=1 11038 MVEADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKMTVDIP 236 44.9 3 10 4 3 1 0.761 0.817 1.108 2 2 2 - - - 0.895333333 0.186290991 tr|H3BR27|H3BR27_HUMAN 100 2.00E-32 gi|343959058|dbj|BAK63384.1| heterogeneous nuclear ribonucleoprotein G [Pan troglodytes] 100 3.00E-33 sp|A5A6M3|RBMX_PANTR RNA-binding motif protein, X chromosome OS=Pan troglodytes GN=RBMX PE=2 SV=1 100 1.00E-31 F1NZD3 F1NZD3_CHICK Uncharacterized protein OS=Gallus gallus GN=RBMX PE=4 SV=1 TP0356 52.8 1.00E-07 COG0724 RNA-binding proteins (RRM domain) R General function prediction only ; K12885|1|4e-37|152|hsa:27316|heterogeneous nuclear ribonucleoprotein G GO:0071347//cellular response to interleukin-1;GO:0007275//multicellular organismal development;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006376//mRNA splice site selection;GO:0006509//membrane protein ectodomain proteolysis;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051260//protein homooligomerization GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0001047//core promoter binding;GO:0003727//single-stranded RNA binding;GO:0003682//chromatin binding;GO:0003729//mRNA binding GO:0005719//nuclear euchromatin;GO:0071013//catalytic step 2 spliceosome;GO:0070062//extracellular vesicular exosome 661 sp|P61158|ARP3_HUMAN Actin-related protein 3 OS=Homo sapiens GN=ACTR3 PE=1 SV=3 >tr|A0A024RAI1|A0A024RAI1_HUMAN ARP3 actin-related protein 3 homolog (Yeast), isoform CRA_a OS=Homo sapiens GN=ACTR3 PE=3 SV=1 55098 MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDFFIGDEAIEKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS 466 37.1 - 25 25 11 11 0.936 0.759 0.771 16 16 17 - * * 0.822 0.098909049 sp|P61158|ARP3_HUMAN 100 0 gi|466042071|ref|XP_004276540.1| PREDICTED: actin-related protein 3-like isoform 3 [Orcinus orca] 100 0 sp|P61158|ARP3_HUMAN Actin-related protein 3 OS=Homo sapiens GN=ACTR3 PE=1 SV=3 100 4.00E-169 F6UPC4 F6UPC4_CALJA Uncharacterized protein OS=Callithrix jacchus GN=ACTR3 PE=3 SV=1 SPAC630.03 488 7.00E-138 COG5277 Actin and related proteins Z Cytoskeleton ; K05692|1|9e-69|261|xla:100036902|actin beta/gamma 1 GO:0050775//positive regulation of dendrite morphogenesis;GO:0007163//establishment or maintenance of cell polarity;GO:0060271//cilium morphogenesis;GO:0046677//response to antibiotic;GO:0051321//meiotic cell cycle;GO:0006928//cellular component movement;GO:0008356//asymmetric cell division;GO:0043519//regulation of myosin II filament organization;GO:0045666//positive regulation of neuron differentiation;GO:0033206//cytokinesis after meiosis;GO:0051653//spindle localization;GO:0010592//positive regulation of lamellipodium assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0009743//response to carbohydrate stimulus;GO:0051491//positive regulation of filopodium assembly GO:0003779//actin binding;GO:0005524//ATP binding GO:0030056//hemidesmosome;GO:0030027//lamellipodium;GO:0000139//Golgi membrane;GO:0005884//actin filament;GO:0060076//excitatory synapse;GO:0005885//Arp2/3 protein complex;GO:0002102//podosome 662 tr|Q8IVC0|Q8IVC0_HUMAN Serpin peptidase inhibitor, clade D (Heparin cofactor), member 1 OS=Homo sapiens GN=SERPIND1 PE=2 SV=1 67435 MKHSLNALLIFLIITSAWGGSKGPLDQLEKGGETAQSADPQWEQLNNKNLSMPLLPADFHKENTVTNDWIPEGEEDDDYLDLEKIFSEDDDYIDIVDSLSVSPTDSDVSAGNILQLFHGKSRIQRLNIVNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQIADFSDPAFISKTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTLEAQLTPGVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISDQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLLFMGRVANPSRS 69 3.2 1 3 3 2 2 1.213 --- --- 2 1 1 - - - 1.213 - tr|Q8IVC0|Q8IVC0_HUMAN 100 0 gi|23273330|gb|AAH35028.1| Serpin peptidase inhibitor, clade D (heparin cofactor), member 1 [Homo sapiens] 99.6 0 sp|P05546|HEP2_HUMAN Heparin cofactor 2 OS=Homo sapiens GN=SERPIND1 PE=1 SV=3 100 0 Q8IVC0 Q8IVC0_HUMAN Serpin peptidase inhibitor, clade D (Heparin cofactor), member 1 OS=Homo sapiens GN=SERPIND1 PE=2 SV=1 all0778 162 1.00E-39 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K03912|1|0.0|1003|hsa:3053|heparin cofactor II GO:0006935//chemotaxis;GO:0010951//negative regulation of endopeptidase activity;GO:0007596//blood coagulation;GO:0030162//regulation of proteolysis GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008201//heparin binding GO:0005576//extracellular region 663 tr|B4E2A3|B4E2A3_HUMAN cDNA FLJ52834, moderately similar to Cold-inducible RNA-binding protein OS=Homo sapiens PE=2 SV=1 17892 MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKVRIRVLSRSLVSRMGHPPANPSRPLSPVCRWTADPSRPGRQVVRQPIPWVPWWLCRGPGLLPWGPRTGPWVL 174 17.6 12 6 6 2 2 1.014 1.236 1.066 5 4 5 - - - 1.105333333 0.116109144 tr|B4E2A3|B4E2A3_HUMAN 100 4.00E-35 gi|426229493|ref|XP_004008825.1| PREDICTED: cold-inducible RNA-binding protein [Ovis aries] 100 5.00E-36 sp|Q14011|CIRBP_HUMAN Cold-inducible RNA-binding protein OS=Homo sapiens GN=CIRBP PE=1 SV=1 100 4.00E-33 Q3SZN4 Q3SZN4_BOVIN Cold inducible RNA binding protein OS=Bos taurus GN=CIRBP PE=2 SV=1 TP0356 62.4 3.00E-10 COG0724 RNA-binding proteins (RRM domain) R General function prediction only ; K13195|1|4e-36|149|ssc:100522851|cold-inducible RNA-binding protein GO:0009411//response to UV;GO:0017148//negative regulation of translation;GO:0009409//response to cold;GO:0048255//mRNA stabilization;GO:0045727//positive regulation of translation;GO:0034063//stress granule assembly GO:0030371//translation repressor activity;GO:0003730//mRNA 3'-UTR binding;GO:0070181//SSU rRNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding GO:0010494//cytoplasmic stress granule;GO:0005654//nucleoplasm 664 sp|P04075|ALDOA_HUMAN Fructose-bisphosphate aldolase A OS=Homo sapiens GN=ALDOA PE=1 SV=2 >tr|V9HWN7|V9HWN7_HUMAN Fructose-bisphosphate aldolase OS=Homo sapiens GN=HEL-S-87p PE=2 SV=1 48065 MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFVSNHAY 850 51.6 - 42 41 11 10 0.509 0.445 0.431 29 30 29 * * * 0.461666667 0.041585254 sp|P04075|ALDOA_HUMAN 100 0 gi|4557305|ref|NP_000025.1| fructose-bisphosphate aldolase A isoform 1 [Homo sapiens] >gi|34577110|ref|NP_908930.1| fructose-bisphosphate aldolase A isoform 1 [Homo sapiens] >gi|34577112|ref|NP_908932.1| fructose-bisphosphate aldolase A isoform 1 [Homo sapiens] >gi|193794814|ref|NP_001121089.1| fructose-bisphosphate aldolase A isoform 1 [Homo sapiens] >gi|113606|sp|P04075.2|ALDOA_HUMAN RecName: Full=Fructose-bisphosphate aldolase A; AltName: Full=Lung cancer antigen NY-LU-1; AltName: Full=Muscle-type aldolase >gi|178351|gb|AAA51690.1| aldolase A (EC 4.1.3.13) [Homo sapiens] >gi|13279257|gb|AAH04333.1| Aldolase A, fructose-bisphosphate [Homo sapiens] >gi|14715001|gb|AAH10660.1| Aldolase A, fructose-bisphosphate [Homo sapiens] >gi|15277571|gb|AAH12880.1| Aldolase A, fructose-bisphosphate [Homo sapiens] >gi|15488981|gb|AAH13614.1| Aldolase A, fructose-bisphosphate [Homo sapiens] >gi|16198435|gb|AAH15888.1| Aldolase A, fructose-bisphosphate [Homo sapiens] >gi|16877049|gb|AAH16800.1| Aldolase A, fructose-bisphosphate [Homo sapiens] >gi|49168540|emb|CAG38765.1| ALDOA [Homo sapiens] >gi|119600339|gb|EAW79933.1| aldolase A, fructose-bisphosphate, isoform CRA_a [Homo sapiens] >gi|119600340|gb|EAW79934.1| aldolase A, fructose-bisphosphate, isoform CRA_a [Homo sapiens] >gi|119600341|gb|EAW79935.1| aldolase A, fructose-bisphosphate, isoform CRA_a [Homo sapiens] >gi|343959624|dbj|BAK63669.1| fructose-bisphosphate aldolase A [Pan troglodytes] 100 0 sp|P04075|ALDOA_HUMAN Fructose-bisphosphate aldolase A OS=Homo sapiens GN=ALDOA PE=1 SV=2 100 0 G2HIW1 G2HIW1_PANTR Fructose-bisphosphate aldolase OS=Pan troglodytes GN=ALDOA PE=2 SV=1 AGl2190 343 4.00E-94 COG3588 Fructose-1,6-bisphosphate aldolase G Carbohydrate transport and metabolism ; K01623|1|0.0|714|hsa:226|fructose-bisphosphate aldolase, class I [EC:4.1.2.13] GO:0006094//gluconeogenesis;GO:0006941//striated muscle contraction;GO:0008360//regulation of cell shape;GO:0030168//platelet activation;GO:0051289//protein homotetramerization;GO:0006000//fructose metabolic process;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0006754//ATP biosynthetic process;GO:0006096//glycolysis;GO:0007015//actin filament organization;GO:0046716//muscle cell homeostasis;GO:0002576//platelet degranulation GO:0003779//actin binding;GO:0042802//identical protein binding;GO:0015631//tubulin binding;GO:0070061//fructose binding;GO:0004332//fructose-bisphosphate aldolase activity GO:0031093//platelet alpha granule lumen;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0031674//I band;GO:0070062//extracellular vesicular exosome 665 tr|A0A023T695|A0A023T695_HUMAN Septin 7 variant 4 OS=Homo sapiens PE=2 SV=1 60777 MLPVANLELLGSSDPSALASQSARITGESGLGKSTLINSLFLTDLYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKNKKKGKIF 148 5.4 14 10 10 2 2 0.887 0.7 0.666 7 7 7 - * * 0.751 0.119 tr|A0A023T695|A0A023T695_HUMAN 100 0 gi|296209064|ref|XP_002751374.1| PREDICTED: septin-7 isoform 3 [Callithrix jacchus] >gi|397527041|ref|XP_003833415.1| PREDICTED: septin-7 isoform 3 [Pan paniscus] >gi|402863733|ref|XP_003896156.1| PREDICTED: septin-7 isoform 2 [Papio anubis] >gi|410952658|ref|XP_003982996.1| PREDICTED: septin-7 isoform 3 [Felis catus] >gi|471407559|ref|XP_004385366.1| PREDICTED: septin-7 isoform 3 [Trichechus manatus latirostris] >gi|194388476|dbj|BAG60206.1| unnamed protein product [Homo sapiens] 99.48 0 sp|Q16181|SEPT7_HUMAN Septin-7 OS=Homo sapiens GN=SEPT7 PE=1 SV=2 100 0 F7IPV7 F7IPV7_CALJA Uncharacterized protein OS=Callithrix jacchus GN=SEPT7 PE=3 SV=1 SPAC4F10.11 305 1.00E-82 COG5019 Septin family protein DZ Cell cycle control, cell division, chromosome partitioning ; Cytoskeleton ; K04557|1|1e-94|347|dre:335925|peanut-like protein 1 (cell division control related protein 1) GO:0060271//cilium morphogenesis;GO:0051291//protein heterooligomerization;GO:0000910//cytokinesis;GO:0016476//regulation of embryonic cell shape;GO:0007067//mitosis GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005525//GTP binding GO:0035085//cilium axoneme;GO:0005730//nucleolus;GO:0030496//midbody;GO:0045202//synapse;GO:0031105//septin complex;GO:0001725//stress fiber;GO:0032154//cleavage furrow;GO:0005819//spindle;GO:0016324//apical plasma membrane;GO:0000777//condensed chromosome kinetochore;GO:0043679//axon terminus 666 tr|B1AVU8|B1AVU8_HUMAN Saposin-D OS=Homo sapiens GN=PSAP PE=1 SV=1 77337 MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYPQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAIQMMMHMQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWIGCWGVGVGSCLWPTWAPTLLSTSGCQETASKASRT 3877 35.2 4 224 59 18 4 1.172 0.859 1.144 49 50 50 * - * 1.058333333 0.173194496 tr|B1AVU8|B1AVU8_HUMAN 100 4.00E-136 gi|119574821|gb|EAW54436.1| prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy), isoform CRA_a [Homo sapiens] 100 0 sp|P07602|SAP_HUMAN Proactivator polypeptide OS=Homo sapiens GN=PSAP PE=1 SV=2 100 0 B1AVU8 B1AVU8_HUMAN Proactivator polypeptide OS=Homo sapiens GN=PSAP PE=4 SV=1 - - - - - - - K12382|1|0.0|966|hsa:5660|saposin GO:0007585//respiratory gaseous exchange;GO:0030168//platelet activation;GO:0006869//lipid transport;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043408//regulation of MAPK cascade;GO:0060736//prostate gland growth;GO:0071310//cellular response to organic substance;GO:0019216//regulation of lipid metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0043065//positive regulation of apoptotic process;GO:0044281//small molecule metabolic process;GO:0002576//platelet degranulation;GO:0045161//neuronal ion channel clustering;GO:0060742//epithelial cell differentiation involved in prostate gland development;GO:0006644//phospholipid metabolic process GO:0030246//carbohydrate binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0005319//lipid transporter activity;GO:0008289//lipid binding GO:0005615//extracellular space;GO:0005743//mitochondrial inner membrane;GO:0016021//integral to membrane;GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0005581//collagen;GO:0043202//lysosomal lumen 667 tr|B0YIW6|B0YIW6_HUMAN Archain 1, isoform CRA_a OS=Homo sapiens GN=ARCN1 PE=1 SV=1 74326 MAECNLVAILISSIDNPLDKNLDNGGNSCLDFRPLNSFSQPQVLLAAAVCTKAGKAIVSRQFVEMTRTRIEGLLAAFPKLMNTGKQHTFVETESVRYVYQPMEKLYMVLITTKNSNILEDLETLRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALGYRENVNLAQIRTFTEMDSHEEKVFRAVRETQEREAKAEMRRKAKELQQARRDAERQGKKAPGFGGFGSSAVSGGSTAAMITETIIETDKPKVAPAPARPSGPSKALKLGAKGKEVDNFVDKLKSEGETIMSSSMGKRTSEATKMHAPPINMESVHMKIEEKITLTCGRDGGLQNMELHGMIMLRISDDKYGRIRLHVENEDKKGVQLQTHPNVDKKLFTAESLIGLKNPEKSFPVNSDVGVLKWRLQTTEESFIPLTINCWPSESGNGCDVNIEYELQEDNLELNDVVITIPLPSGVGAPVIGEIDGEYRHDSRRNTLEWCLPVIDAKNKSGSLEFSIAGQPNDFFPVQVSFVSKKNYCNIQVTKVTQVDGNSPVRFSTETTFLVDKYEIL 204 12.7 2 11 11 6 6 0.885 0.847 0.962 6 6 6 - - - 0.898 0.058591808 tr|B0YIW6|B0YIW6_HUMAN 100 4.00E-28 gi|301631615|ref|XP_002944893.1| PREDICTED: LOW QUALITY PROTEIN: coatomer subunit delta-like, partial [Xenopus (Silurana) tropicalis] 100 0 sp|P48444|COPD_HUMAN Coatomer subunit delta OS=Homo sapiens GN=ARCN1 PE=1 SV=1 100 0 H2Q4W6 H2Q4W6_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000095139 PE=4 SV=1 - - - - - - - - GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0048205//COPI coating of Golgi vesicle;GO:0006886//intracellular protein transport GO:0005515//protein binding GO:0030126//COPI vesicle coat;GO:0005829//cytosol;GO:0030131//clathrin adaptor complex 668 tr|Q53GU8|Q53GU8_HUMAN Transforming growth factor, beta-induced, 68kDa variant (Fragment) OS=Homo sapiens PE=2 SV=1 85574 MALFVRLLALALALALGPAATLAGPAKSPYQLVLQHSRLRGRQHGPNVCAVQKVIGTNRKYFTNCKQWYQRKICGKSTVISYECCPGYEKVPGEKGCPAALPLSNLYETLGVVGSTTTQLYTDRTEKLRPEMEGPGSFTIFAPSNEAWASLPAEVLDSLVSNVNIELLNALRYHMVGRRVLTDELKHGMTLTSMYQNSNIQIHHYPNGIVTVNCARLLKADHHATNGVVHLIDKVISTITNNIQQIIEIEDTFETLRAAVAASGLNTMLEGNGQYTLLAPTNEAFEKIPSETLNRILGDPEALRDLLNNHILKSAMCAEAIVAGLSVETLEGTTLEVGCSGDMLTINGKAIISNKDILATNGVIHYIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGGERLTLLAPLNSVFKDGTPPIDAHTRNLLRNHIIKDQLASKYLYHGQTLETLGGKKLRVFVYRNSLCIENSCIAAHDKRGRYGTLFTMDRVLTPPMGTVMDVLKGDNRFSMLVAAIQSAGLTETLNREGVYTVFAPTNEAFRALPPRERSRLLGDAKELANILKYHIGDEILVSGGIGALVRLKSLQGDKLEVSLKNNVVSVNKEPVAEPDIMATNGVVHVITNVLQPPANRPQERGDELADSALEIFKQASAFSRASQRSVRLAPVYQKLLERMKH 2157 28.3 1 107 107 15 15 1.142 0.818 0.957 69 71 71 - * - 0.972333333 0.162543328 tr|Q53GU8|Q53GU8_HUMAN 100 3.00E-102 gi|3282161|gb|AAC24944.1| BIGH3 [Homo sapiens] 99.85 0 sp|Q15582|BGH3_HUMAN Transforming growth factor-beta-induced protein ig-h3 OS=Homo sapiens GN=TGFBI PE=1 SV=1 100 0 Q53GU8 Q53GU8_HUMAN Transforming growth factor, beta-induced, 68kDa variant (Fragment) OS=Homo sapiens PE=2 SV=1 all4894 99.8 1.00E-20 COG2335 Secreted and surface protein containing fasciclin-like repeats M Cell wall/membrane/envelope biogenesis ; - GO:0001525//angiogenesis;GO:0050896//response to stimulus;GO:0008283//cell proliferation;GO:0007601//visual perception;GO:0030198//extracellular matrix organization;GO:0007162//negative regulation of cell adhesion GO:0050840//extracellular matrix binding;GO:0005178//integrin binding GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix 669 tr|B3KR70|B3KR70_HUMAN cDNA FLJ33764 fis, clone BRCOC2000360, highly similar to Vacuolar ATP synthase subunit S1 (EC 3.6.3.14) OS=Homo sapiens PE=2 SV=1 51864 MRPRLTAPLLCPARDLWAPAADTHEGHITSDLQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFSNLENALDLAPSSLVLPAVDWYAVSTLTTYLQEKLGASPLHVDLATLRELKLNASLPALLLIRLPYTASSGLMAPREVLTGNDEVIGQVLSTLKSEDVPYTAALTAVRPSRVARDVAVVAGGLGRQLLQKQPVSPVIHPPVSYNDTAPRILFWAQNFSVAYKDQWEDLTPLTFGVQELNLTGSFWNDSFARLSLTYERLFGTTVTFKFILANRLYPVSARHWFTMERLEVHSNGSVAYFNASQVTGSSIYSFHCEYVSSLSKKGSLLVARTQPSPWQMMLQDFQIQAFNVMGEQFSYASDCASFFSPGIWMGLLTSLFMLFIFTYGLHMILSLKTMDRFDDHKGPTISLTQIV 317 14 1 12 12 4 4 0.873 0.659 0.741 7 8 8 - * * 0.757666667 0.107969131 tr|B3KR70|B3KR70_HUMAN 100 0 gi|193786959|dbj|BAG52282.1| unnamed protein product [Homo sapiens] 99.76 0 sp|Q15904|VAS1_HUMAN V-type proton ATPase subunit S1 OS=Homo sapiens GN=ATP6AP1 PE=1 SV=2 100 9.00E-54 A6NLC6 A6NLC6_HUMAN ATPase, H+ transporting, lysosomal accessory protein 1 (Fragment) OS=Homo sapiens GN=ATP6AP1 PE=4 SV=3 - - - - - - - K03662|1|0.0|749|hsa:537|V-type H+-transporting ATPase S1 subunit [EC:3.6.3.14] GO:0008219//cell death;GO:0007568//aging;GO:0015991//ATP hydrolysis coupled proton transport GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0005524//ATP binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism GO:0016021//integral to membrane;GO:0005774//vacuolar membrane;GO:0033180//proton-transporting V-type ATPase, V1 domain 670 tr|A8K486|A8K486_HUMAN Peptidyl-prolyl cis-trans isomerase OS=Homo sapiens PE=2 SV=1 22489 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGETSKKITIADCGQLE 698 35.8 1 64 64 7 7 0.767 0.619 0.719 29 31 31 * - - 0.701666667 0.075507174 tr|A8K486|A8K486_HUMAN 100 3.00E-92 gi|158255138|dbj|BAF83540.1| unnamed protein product [Homo sapiens] 99.39 1.00E-92 sp|Q0ZQK7|PPIA_NOMLE Peptidyl-prolyl cis-trans isomerase A OS=Nomascus leucogenys GN=PPIA PE=3 SV=3 100 1.00E-91 A8K486 A8K486_HUMAN Peptidyl-prolyl cis-trans isomerase OS=Homo sapiens PE=2 SV=1 SPBC28F2.03 233 9.00E-62 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family O Posttranslational modification, protein turnover, chaperones ; K03767|1|1e-92|338|mcc:574102|peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] - - 671 tr|Q60FE5|Q60FE5_HUMAN Filamin A OS=Homo sapiens GN=FLNA PE=1 SV=1 329767 MPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPMGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEALVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPGLGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVPCFDASKVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP 10134 37.6 2 445 421 66 62 0.753 0.705 0.563 286 296 281 - - - 0.673666667 0.09879946 tr|Q60FE5|Q60FE5_HUMAN 100 0 gi|160420317|ref|NP_001104026.1| filamin-A isoform 2 [Homo sapiens] >gi|116241365|sp|P21333.4|FLNA_HUMAN RecName: Full=Filamin-A; Short=FLN-A; AltName: Full=Actin-binding protein 280; Short=ABP-280; AltName: Full=Alpha-filamin; AltName: Full=Endothelial actin-binding protein; AltName: Full=Filamin-1; AltName: Full=Non-muscle filamin >gi|1203969|gb|AAA92644.1| filamin [Homo sapiens] >gi|119593151|gb|EAW72745.1| filamin A, alpha (actin binding protein 280), isoform CRA_b [Homo sapiens] >gi|317040158|gb|ADU87644.1| epididymis secretory sperm binding protein Li 190P [Homo sapiens] >gi|326205158|dbj|BAJ83965.1| filamin A [Homo sapiens] 100 0 sp|P21333|FLNA_HUMAN Filamin-A OS=Homo sapiens GN=FLNA PE=1 SV=4 100 0 Q6NXF2 Q6NXF2_HUMAN FLNA protein (Fragment) OS=Homo sapiens GN=FLNA PE=2 SV=1 ECU09g0290 151 2.00E-35 COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) Z Cytoskeleton ; K04437|1|0.0|5128|hsa:2316|filamin GO:0030168//platelet activation;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0051220//cytoplasmic sequestering of protein;GO:0050821//protein stabilization;GO:0034394//protein localization to cell surface;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0051764//actin crosslink formation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB cascade;GO:0034329//cell junction assembly;GO:0042384//cilium assembly;GO:0002576//platelet degranulation;GO:0090307//spindle assembly involved in mitosis;GO:0031532//actin cytoskeleton reorganization;GO:0042177//negative regulation of protein catabolic process;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0043113//receptor clustering GO:0004871//signal transducer activity;GO:0001948//glycoprotein binding;GO:0017160//Ral GTPase binding;GO:0051015//actin filament binding;GO:0048365//Rac GTPase binding;GO:0042803//protein homodimerization activity;GO:0034988//Fc-gamma receptor I complex binding;GO:0008134//transcription factor binding GO:0015629//actin cytoskeleton;GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0031523//Myb complex;GO:0005938//cell cortex 672 sp|P42785|PCP_HUMAN Lysosomal Pro-X carboxypeptidase OS=Homo sapiens GN=PRCP PE=1 SV=1 >tr|A0A024R5L0|A0A024R5L0_HUMAN Prolylcarboxypeptidase (Angiotensinase C), isoform CRA_a OS=Homo sapiens GN=PRCP PE=4 SV=1 63578 MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH 92 10.9 - 5 5 4 4 1.313 1.328 1.413 5 5 4 * - * 1.351333333 0.053928966 sp|P42785|PCP_HUMAN 100 2.00E-71 gi|193786915|dbj|BAG52238.1| unnamed protein product [Homo sapiens] 100 0 sp|P42785|PCP_HUMAN Lysosomal Pro-X carboxypeptidase OS=Homo sapiens GN=PRCP PE=1 SV=1 100 6.00E-81 E9PQB5 E9PQB5_HUMAN Lysosomal Pro-X carboxypeptidase (Fragment) OS=Homo sapiens GN=PRCP PE=4 SV=1 - - - - - - - K01285|1|0.0|1024|hsa:5547|lysosomal Pro-X carboxypeptidase [EC:3.4.16.2] GO:0007597//blood coagulation, intrinsic pathway;GO:0006508//proteolysis GO:0004185//serine-type carboxypeptidase activity;GO:0005515//protein binding GO:0005886//plasma membrane;GO:0005764//lysosome 673 tr|A0A024RC59|A0A024RC59_HUMAN Milk fat globule-EGF factor 8 protein, isoform CRA_b OS=Homo sapiens GN=MFGE8 PE=4 SV=1 43164 MPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKGYAGNHCETKCVEPLGMENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 166 18.8 3 11 11 5 5 1.238 1.006 0.883 7 8 8 - - - 1.042333333 0.180267394 tr|A0A024RC59|A0A024RC59_HUMAN 100 0 gi|13177648|gb|AAH03610.1| MFGE8 protein [Homo sapiens] >gi|30582735|gb|AAP35594.1| milk fat globule-EGF factor 8 protein [Homo sapiens] >gi|119622431|gb|EAX02026.1| milk fat globule-EGF factor 8 protein, isoform CRA_b [Homo sapiens] >gi|119622434|gb|EAX02029.1| milk fat globule-EGF factor 8 protein, isoform CRA_b [Homo sapiens] 86.56 0 sp|Q08431|MFGM_HUMAN Lactadherin OS=Homo sapiens GN=MFGE8 PE=1 SV=2 97.85 1.00E-121 H0YKS8 H0YKS8_HUMAN Lactadherin short form (Fragment) OS=Homo sapiens GN=MFGE8 PE=4 SV=1 - - - - - - - K03902|1|2e-51|202|mdo:100019396|coagulation factor V (labile factor) GO:2000427//positive regulation of apoptotic cell clearance;GO:0001525//angiogenesis;GO:0006910//phagocytosis, recognition;GO:0043627//response to estrogen stimulus;GO:0006911//phagocytosis, engulfment;GO:0007155//cell adhesion;GO:0019048//virus-host interaction;GO:0008284//positive regulation of cell proliferation;GO:0007338//single fertilization GO:0008429//phosphatidylethanolamine binding;GO:0005178//integrin binding;GO:0001786//phosphatidylserine binding GO:0009897//external side of plasma membrane;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0019897//extrinsic to plasma membrane 674 tr|E9PMR4|E9PMR4_HUMAN Tetraspanin OS=Homo sapiens GN=CD151 PE=1 SV=1 32858 MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQRDHASNIYKGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY 70 4 1 2 2 1 1 0.858 0.656 --- 2 2 1 - - - 0.757 0.14283557 tr|E9PMR4|E9PMR4_HUMAN 100 7.00E-33 gi|119622806|gb|EAX02401.1| CD151 antigen (Raph blood group), isoform CRA_b [Homo sapiens] >gi|119622808|gb|EAX02403.1| CD151 antigen (Raph blood group), isoform CRA_b [Homo sapiens] >gi|119622809|gb|EAX02404.1| CD151 antigen (Raph blood group), isoform CRA_b [Homo sapiens] 99.21 6.00E-120 sp|P48509|CD151_HUMAN CD151 antigen OS=Homo sapiens GN=CD151 PE=1 SV=3 100 6.00E-120 E9PMR4 E9PMR4_HUMAN CD151 antigen OS=Homo sapiens GN=CD151 PE=4 SV=1 - - - - - - - K06537|1|6e-120|430|hsa:977|CD151 antigen GO:0016477//cell migration;GO:0031581//hemidesmosome assembly;GO:0042098//T cell proliferation;GO:0007155//cell adhesion GO:0005515//protein binding GO:0005887//integral to plasma membrane;GO:0005829//cytosol 675 tr|D3DQU2|D3DQU2_HUMAN Tripeptidyl peptidase I, isoform CRA_a OS=Homo sapiens GN=TPP1 PE=4 SV=1 65777 MTADPRKGRMGLQACLLGLFALILSGKCSYSPEPDQRRTLPPGWVSLGRADPEEELSLTFALRQQNVERLSELVQAVSDPSSPQYGKYLTLENVADLVRPSPLTLHTVQKWLLAAGAQKCHSVITQDFLTCWLSIRQAELLLPGAEFHHYVGGPTETHVVRSPHPYQLPQALAPHVDFVGGLHRFPPTSSLRQRPEPQVTGTVGLHLGVTPSVIRKRYNLTSQDVGSGTSNNSQACAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEGQEPFLQWLMLLSNESALPHVHTVSYGDDEDSLSSAYIQRVNTELMKAAARGLTLLFASGDSGAGCWSVSGRHQFRPTFPASSPYVTTVGGTSFQEPFLITNEIVDYISGGGFSNVFPRPSYQEEAVTKFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGTSASTPVFGGILSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTRGCHESCLDEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP 1486 29.5 1 80 80 10 10 1.557 1.25 1.924 44 47 44 - - - 1.577 0.33744481 tr|D3DQU2|D3DQU2_HUMAN 100 1.00E-169 gi|34452679|gb|AAQ72732.1| growth-inhibiting protein 1 [Homo sapiens] 100 0 sp|O14773|TPP1_HUMAN Tripeptidyl-peptidase 1 OS=Homo sapiens GN=TPP1 PE=1 SV=2 100 4.00E-81 E7EV34 E7EV34_HUMAN Tripeptidyl-peptidase 1 (Fragment) OS=Homo sapiens GN=TPP1 PE=4 SV=2 CAC0625 99.4 2.00E-20 COG4934 Predicted protease O Posttranslational modification, protein turnover, chaperones ; K01279|1|0.0|1097|mcc:709838|tripeptidyl-peptidase I [EC:3.4.14.9] GO:0042360//vitamin E metabolic process;GO:0030326//embryonic limb morphogenesis;GO:0050885//neuromuscular process controlling balance;GO:0007584//response to nutrient;GO:0001501//skeletal system development;GO:0090212//negative regulation of establishment of blood-brain barrier;GO:0043171//peptide catabolic process;GO:0035282//segmentation;GO:0060381//positive regulation of single-stranded telomeric DNA binding;GO:0031848//protection from non-homologous end joining at telomere;GO:0070198//protein localization to chromosome, telomeric region;GO:0006629//lipid metabolic process;GO:0009268//response to pH;GO:0006508//proteolysis;GO:0001892//embryonic placenta development;GO:0007399//nervous system development;GO:0006886//intracellular protein transport;GO:0008219//cell death;GO:0032202//telomere assembly;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0045453//bone resorption;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0009636//response to toxic substance;GO:0051973//positive regulation of telomerase activity;GO:0030163//protein catabolic process;GO:0001655//urogenital system development;GO:0007040//lysosome organization GO:0008431//vitamin E binding;GO:0005215//transporter activity;GO:0070182//DNA polymerase binding;GO:0046872//metal ion binding;GO:0042277//peptide binding;GO:0008240//tripeptidyl-peptidase activity;GO:0003677//DNA binding;GO:0004252//serine-type endopeptidase activity GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0000783//nuclear telomere cap complex;GO:0043202//lysosomal lumen;GO:0005739//mitochondrion;GO:0042470//melanosome;GO:0005770//late endosome 676 tr|E7EQG2|E7EQG2_HUMAN Eukaryotic initiation factor 4A-II OS=Homo sapiens GN=EIF4A2 PE=1 SV=1 47881 MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRSR 96 19.9 1 11 2 6 2 1.074 1.277 1.366 2 2 2 - - - 1.239 0.149662955 tr|E7EQG2|E7EQG2_HUMAN 100 0 gi|148665241|gb|EDK97657.1| eukaryotic translation initiation factor 4A2, isoform CRA_c [Mus musculus] 100 0 sp|Q14240|IF4A2_HUMAN Eukaryotic initiation factor 4A-II OS=Homo sapiens GN=EIF4A2 PE=1 SV=2 100 0 A6M930 A6M930_PIG Eukaryotic translation initiation factor 4A isoform 2 OS=Sus scrofa GN=EIF4A2 PE=2 SV=1 SPAC1006.07 544 1.00E-154 COG0513 Superfamily II DNA and RNA helicases LKJ Replication, recombination and repair ; Transcription ; Translation, ribosomal structure and biogenesis ; K03257|1|0.0|749|ecb:100068164|translation initiation factor 4A GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0019221//cytokine-mediated signaling pathway;GO:0006446//regulation of translational initiation;GO:0019048//virus-host interaction GO:0003743//translation initiation factor activity;GO:0008026//ATP-dependent helicase activity;GO:0005524//ATP binding;GO:0005515//protein binding GO:0016281//eukaryotic translation initiation factor 4F complex;GO:0005829//cytosol 677 tr|B7ZKY6|B7ZKY6_HUMAN Membrane metallo-endopeptidase OS=Homo sapiens GN=MME PE=2 SV=1 103179 MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMKNAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 53 6.5 1 5 5 4 4 1.168 1.513 1.701 2 2 2 - - - 1.460666667 0.270326346 tr|B7ZKY6|B7ZKY6_HUMAN 100 0 gi|219517850|gb|AAI43466.1| Membrane metallo-endopeptidase [Homo sapiens] 99.87 0 sp|P08473|NEP_HUMAN Neprilysin OS=Homo sapiens GN=MME PE=1 SV=2 100 0 B7ZKY6 B7ZKY6_HUMAN Membrane metallo-endopeptidase OS=Homo sapiens GN=MME PE=2 SV=1 ML2613 319 1.00E-86 COG3590 Predicted metalloendopeptidase O Posttranslational modification, protein turnover, chaperones ; K01389|1|0.0|1445|hsa:4311|neprilysin [EC:3.4.24.11] GO:0090399//replicative senescence;GO:0071345//cellular response to cytokine stimulus;GO:0019233//sensory perception of pain;GO:0071493//cellular response to UV-B;GO:0071492//cellular response to UV-A;GO:0006508//proteolysis;GO:0046449//creatinine metabolic process;GO:0050435//beta-amyloid metabolic process;GO:0001822//kidney development GO:0042277//peptide binding;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding GO:0030424//axon;GO:0030425//dendrite;GO:0005903//brush border;GO:0008021//synaptic vesicle;GO:0044306//neuron projection terminus;GO:0005887//integral to plasma membrane 678 tr|Q5VVC8|Q5VVC8_HUMAN 60S ribosomal protein L11 (Fragment) OS=Homo sapiens GN=RPL11 PE=1 SV=1 25642 QDQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKVKLIYLK 43 8 3 2 2 1 1 1.602 0.568 0.744 2 2 2 - - - 0.971333333 0.553217257 tr|Q5VVC8|Q5VVC8_HUMAN 100 5.00E-67 gi|402697566|gb|AFQ90968.1| ribosomal protein L11, partial [Cyrtodactylus sp. JJF-2012] >gi|402697572|gb|AFQ90971.1| ribosomal protein L11, partial [Draco sumatranus] 97.69 9.00E-95 sp|Q9CXW4|RL11_MOUSE 60S ribosomal protein L11 OS=Mus musculus GN=Rpl11 PE=1 SV=4 100 5.00E-97 Q5VVC8 Q5VVC8_HUMAN 60S ribosomal protein L11 (Fragment) OS=Homo sapiens GN=RPL11 PE=2 SV=1 SPBC17G9.10 260 9.00E-70 COG0094 Ribosomal protein L5 J Translation, ribosomal structure and biogenesis ; K15076|1|5e-97|353|mcc:710467|transcription elongation factor B, polypeptide 3!K02868|2|9e-95|345|cfa:100684296|large subunit ribosomal protein L11e GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006364//rRNA processing;GO:0042273//ribosomal large subunit biogenesis;GO:0006414//translational elongation;GO:0034504//protein localization to nucleus;GO:0006415//translational termination;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0019843//rRNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding GO:0005730//nucleolus;GO:0022625//cytosolic large ribosomal subunit 679 tr|A0A024RAM4|A0A024RAM4_HUMAN Microtubule-associated protein 1B, isoform CRA_b OS=Homo sapiens GN=MAP1B PE=4 SV=1 342531 MATVVVEATEPEPSGSIANPAASTSPSLSHRFLDSKFYLLVVVGEIVTEEHLRRAIGNIELGIRSWDTNLIECNLDQELKLFVSRHSARFSPEVPGQKILHHRSDVLETVVLINPSDEAVSTEVRLMITDAARHKLLVLTGQCFENTGELILQSGSFSFQNFIEIFTDQEIGELLSTTHPANKASLTLFCPEEGDWKNSNLDRHNLQDFINIKLNSASILPEMEGLSEFTEYLSESVEVPSPFDILEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSERKSCFWKLIRHLDRVDSILLTHIGDDNLPGINSMLQRKIAELEEEQSQGSTTNSDWMKNLISPDLGVVFLNVPENLKNPEPNIKMKRSIEEACFTLQYLNKLSMKPEPLFRSVGNTIDPVILFQKMGVGKLEMYVLNPVKSSKEMQYFMQQWTGTNKDKAEFILPNGQEVDLPISYLTSVSSLIVWHPANPAEKIIRVLFPGNSTQYNILEGLEKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPVKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISSEPTPMDEMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYSQEYSKPADVTPLNGFSEGSKTDATDGKDYNASASTISPPSSMEEDKFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKVSPSKSPSLSPSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVSPEVTQEVVEEHCASPEDKTLEVVSPSQSVTGSAGHTPYYQSPTDEKSSHLPTEVIEKPPAVPVSFEFSDAKDENERASVSPMDEPVPDSESPIEKVLSPLRSPPLIGSESAYESFLSADDKASGRGAESPFEEKSGKQGSPDQVSPVSEMTSTSLYQDKQEGKSTDFAPIKEDFGQEKKTDDVEAMSSQPALALDERKLGDVSPTQIDVSQFGSFKEDTKMSISEGTVSDKSATPVDEGVAEDTYSHMEGVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPMSISPPDFSPKTAKSRTPVQDHRSEQSSMSIEFGQESPEQSLAMDFSRQSPDHPTVGAGVLHITENGPTEVDYSPSDMQDSSLSHKIPPMEEPSYTQDNDLSELISVSQVEASPSTSSAHTPSQIASPLQEDTLSDVAPPRDMSLYASLTSEKVQSLEGEKLSPKSDISPLTPRESSPLYSPTFSDSTSAVKEKTATCHSSSSPPIDAASAEPYGFRASVLFDTMQHHLALNRDLSTPGLEKDSGGKTPGDFSYAYQKPEETTRSPDEEDYDYESYEKTTRTSDVGGYYYEKIERTTKSPSDSGYSYETIGKTTKTPEDGDYSYEIIEKTTRTPEEGGYSYDISEKTTSPPEVSGYSYEKTERSRRLLDDISNGYDDSEDGGHTLGDPSYSYETTEKITSFPESEGYSYETSTKTTRTPDTSTYCYETAEKITRTPQASTYSYETSDLCYTAEKKSPSEARQDVDLCLVSSCEYKHPKTELSPSFINPNPLEWFASEEPTEESEKPLTQSGGAPPPPGGKQQGRQCDETPPTSVSESAPSQTDSDVPPETEECPSITADANIDSEDESETIPTDKTVTYKHMDPPPAPVQDRSPSPRHPDVSMVDPEALAIEQNLGKALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGTTKTTKSSAVPPGLPVYLDLCYIPNHSNSKNVDVEFFKRVRSSYYVVSGNDPAAEEPSRAVLDALLEGKAQWGSNMQVTLIPTHDSEVMREWYQETHEKQQDLNIMVLASSSTVVMQDESFPACKIEL 345 8.1 2 27 21 15 14 0.682 0.867 0.827 11 14 12 * - - 0.792 0.097339612 tr|A0A024RAM4|A0A024RAM4_HUMAN 100 0 gi|119616105|gb|EAW95699.1| microtubule-associated protein 1B, isoform CRA_d [Homo sapiens] 100 0 sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=2 100 1.00E-119 Q6UIN8 Q6UIN8_PANTR Microtubule-associated protein 1B (Fragment) OS=Pan troglodytes GN=MAP1B PE=2 SV=1 - - - - - - - K10429|1|0.0|2632|hsa:4131|microtubule-associated protein 1 GO:0016358//dendrite development;GO:0051915//induction of synaptic plasticity by chemical substance;GO:0007026//negative regulation of microtubule depolymerization;GO:0007417//central nervous system development;GO:0033189//response to vitamin A;GO:0061162//establishment of monopolar cell polarity;GO:0009612//response to mechanical stimulus;GO:0017085//response to insecticide;GO:0021700//developmental maturation;GO:0043434//response to peptide hormone stimulus;GO:0045773//positive regulation of axon extension;GO:0014012//peripheral nervous system axon regeneration;GO:0009790//embryo development;GO:0042493//response to drug;GO:0001578//microtubule bundle formation;GO:0045666//positive regulation of neuron differentiation;GO:0010035//response to inorganic substance;GO:0047497//mitochondrion transport along microtubule;GO:0032387//negative regulation of intracellular transport;GO:0009743//response to carbohydrate stimulus;GO:0031116//positive regulation of microtubule polymerization;GO:0007416//synapse assembly;GO:0032355//response to estradiol stimulus GO:0005198//structural molecule activity;GO:0003779//actin binding;GO:0008017//microtubule binding;GO:0032403//protein complex binding GO:0030426//growth cone;GO:0005829//cytosol;GO:0005874//microtubule;GO:0030424//axon;GO:0014069//postsynaptic density;GO:0005875//microtubule associated complex;GO:0030054//cell junction;GO:0048471//perinuclear region of cytoplasm;GO:0005886//plasma membrane;GO:0043204//perikaryon 680 tr|B4DZF8|B4DZF8_HUMAN Serine/threonine-protein phosphatase 2A activator OS=Homo sapiens PE=2 SV=1 50194 MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEMWNEVHEEKEQAAKQSVSCDECIPLPRAGHCAPSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEASPSDTWGLGISHLGHGQSEKHQPPQPRKAAVQLCPDELGG 49 5.3 6 4 4 2 2 1.137 0.977 0.654 2 2 2 - - - 0.922666667 0.246041324 tr|B4DZF8|B4DZF8_HUMAN 100 0 gi|194381004|dbj|BAG64070.1| unnamed protein product [Homo sapiens] 99.7 0 sp|Q15257|PTPA_HUMAN Serine/threonine-protein phosphatase 2A activator OS=Homo sapiens GN=PPP2R4 PE=1 SV=3 100 7.00E-64 C9IZ76 C9IZ76_HUMAN Serine/threonine-protein phosphatase 2A activator (Fragment) OS=Homo sapiens GN=PPP2R4 PE=4 SV=1 SPAC4F10.04 195 1.00E-49 COG5057 Phosphotyrosyl phosphatase activator DT Cell cycle control, cell division, chromosome partitioning ; Signal transduction mechanisms ; - GO:0035308//negative regulation of protein dephosphorylation;GO:0006457//protein folding;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0035307//positive regulation of protein dephosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0006200//ATP catabolic process GO:0051721//protein phosphatase 2A binding;GO:0005102//receptor binding;GO:0046982//protein heterodimerization activity;GO:0008601//protein phosphatase type 2A regulator activity;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016887//ATPase activity;GO:0042803//protein homodimerization activity;GO:0005524//ATP binding;GO:0008160//protein tyrosine phosphatase activator activity GO:0034704//calcium channel complex;GO:0000159//protein phosphatase type 2A complex;GO:0005737//cytoplasm;GO:0005730//nucleolus 681 tr|A0A024QZN4|A0A024QZN4_HUMAN Vinculin, isoform CRA_c OS=Homo sapiens GN=VCL PE=4 SV=1 140643 MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ 2406 31.9 1 134 134 30 30 0.886 0.865 0.732 86 87 83 - - - 0.827666667 0.083512474 tr|A0A024QZN4|A0A024QZN4_HUMAN 100 5.00E-148 gi|345531895|pdb|3TJ5|A Chain A, Human Vinculin Head Domain (Vh1, Residues 1-258) In Complex With The Vinculin Binding Site Of The Surface Cell Antigen 4 (Sca4-Vbs-N; Residues 412-434) From Rickettsia Rickettsii 100 0 sp|P18206|VINC_HUMAN Vinculin OS=Homo sapiens GN=VCL PE=1 SV=4 100 9.00E-63 B4DTM7 B4DTM7_HUMAN Uncharacterized protein OS=Homo sapiens GN=VCL PE=2 SV=1 - - - - - - - K05700|1|0.0|1971|hsa:7414|vinculin GO:0030336//negative regulation of cell migration;GO:0030032//lamellipodium assembly;GO:0030168//platelet activation;GO:0007160//cell-matrix adhesion;GO:0090136//epithelial cell-cell adhesion;GO:0006936//muscle contraction;GO:0034394//protein localization to cell surface;GO:0034333//adherens junction assembly;GO:0002009//morphogenesis of an epithelium;GO:0043297//apical junction assembly;GO:0002576//platelet degranulation GO:0005198//structural molecule activity;GO:0045296//cadherin binding;GO:0045294//alpha-catenin binding;GO:0003779//actin binding;GO:0002162//dystroglycan binding;GO:0017048//Rho GTPase binding;GO:0008013//beta-catenin binding GO:0005925//focal adhesion;GO:0005884//actin filament;GO:0043034//costamere;GO:0005576//extracellular region;GO:0005829//cytosol;GO:0042383//sarcolemma;GO:0001725//stress fiber;GO:0030018//Z disc;GO:0005916//fascia adherens 682 tr|A0A087WX80|A0A087WX80_HUMAN Laminin subunit alpha-2 OS=Homo sapiens GN=LAMA2 PE=4 SV=1 409406 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNTVADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTYKPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAMLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYAILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCPAN 1336 11.2 2 64 64 27 27 1.412 1.292 1.592 48 46 48 * * * 1.432 0.150996689 tr|A0A087WX80|A0A087WX80_HUMAN 99.9 0 gi|119568466|gb|EAW48081.1| laminin, alpha 2 (merosin, congenital muscular dystrophy), isoform CRA_b [Homo sapiens] 99.9 0 sp|P24043|LAMA2_HUMAN Laminin subunit alpha-2 OS=Homo sapiens GN=LAMA2 PE=1 SV=4 100 0 F8WAH5 F8WAH5_HUMAN Laminin subunit alpha-2 OS=Homo sapiens GN=LAMA2 PE=4 SV=1 PH0929 71.6 2.00E-11 COG0419 ATPase involved in DNA repair L Replication, recombination and repair ; K05637|1|0.0|6237|hsa:3908|laminin, alpha 1/2 GO:0007411//axon guidance;GO:0030155//regulation of cell adhesion;GO:0045995//regulation of embryonic development;GO:0007517//muscle organ development;GO:0030334//regulation of cell migration;GO:0032224//positive regulation of synaptic transmission, cholinergic GO:0005102//receptor binding;GO:0005198//structural molecule activity GO:0005606//laminin-1 complex;GO:0042383//sarcolemma 683 tr|A6NFX8|A6NFX8_HUMAN ADP-sugar pyrophosphatase OS=Homo sapiens GN=NUDT5 PE=1 SV=1 31640 MESQEPTESSQNGKQYIISEELISEGKWVKLEKTTYMDPTGKTRRNKEKTTTLLILRTWESVKRTTRKEQTADGVAVIPVLQRTLHYECIVLVKQFRPPMGGYCIEFPAGLIDDGETPEAAALRELEEETGYKGDIAECSPAVCMDPGLSNCTIHIVTVTINGDDAENARPKPKPGDGEFVEVISLPKNDLLQRLDALVAEEHLTVDARVYSYALALKHANAKPFEVPFLKF 163 21.1 1 9 9 4 4 1.002 0.832 0.968 4 4 4 - * - 0.934 0.089955545 tr|A6NFX8|A6NFX8_HUMAN 97.41 1.00E-123 gi|355782640|gb|EHH64561.1| hypothetical protein EGM_17806 [Macaca fascicularis] 94.4 7.00E-118 sp|Q9UKK9|NUDT5_HUMAN ADP-sugar pyrophosphatase OS=Homo sapiens GN=NUDT5 PE=1 SV=1 100 8.00E-127 A6NFX8 A6NFX8_HUMAN ADP-sugar pyrophosphatase OS=Homo sapiens GN=NUDT5 PE=3 SV=1 YBR111c 135 8.00E-32 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes LR Replication, recombination and repair ; General function prediction only ; K13987|1|7e-118|422|hsa:11164|ADP-sugar pyrophosphatase [EC:3.6.1.13 3.6.1.-] GO:0019303//D-ribose catabolic process;GO:0009191//ribonucleoside diphosphate catabolic process;GO:0009117//nucleotide metabolic process GO:0047631//ADP-ribose diphosphatase activity;GO:0019144//ADP-sugar diphosphatase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0000287//magnesium ion binding GO:0005622//intracellular 684 tr|Q5RLJ0|Q5RLJ0_HUMAN CLE OS=Homo sapiens PE=2 SV=1 34150 MFRRKLTALDYHNPAGFNCKDETEFRNFIVWLEDQKIGHYKIEDRGNLRNIHSSDWPKFFEKYLRDVNCPFKIQDRQEAIDWLLGLAVRLEYGDNAEKYKDLVPDNSKTADNATKNAEPLINLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDAVAKANQTKEGLPVALDKHILGFDTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLGKVGR 72 9.8 1 4 4 2 2 0.818 1 1.862 2 2 2 - - - 1.226666667 0.55768928 tr|Q5RLJ0|Q5RLJ0_HUMAN 100 2.00E-131 gi|55613379|gb|AAV54070.1| CLE [Homo sapiens] 99.59 3.00E-131 sp|Q9Y224|CN166_HUMAN UPF0568 protein C14orf166 OS=Homo sapiens GN=C14orf166 PE=1 SV=1 100 7.00E-131 Q5RLJ0 Q5RLJ0_HUMAN CLE OS=Homo sapiens PE=2 SV=1 - - - - - - - K15433|1|3e-131|467|mcc:710094|RLL motif containing protein 1 GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0019048//virus-host interaction GO:0000993//RNA polymerase II core binding;GO:0042802//identical protein binding;GO:0003677//DNA binding GO:0005815//microtubule organizing center;GO:0005730//nucleolus;GO:0072669//tRNA-splicing ligase complex;GO:0048471//perinuclear region of cytoplasm 685 tr|H0YG20|H0YG20_HUMAN alpha-1,2-Mannosidase OS=Homo sapiens GN=MAN1B1 PE=3 SV=2 89780 MYPPPPPPPHRDFISVTLSFGENYDNSKSWRRRSCWRKWKQLSRLQRNMILFLLAFLLFCGLLFYINLADHWKALAFRLEEEQKMRPEIAGLKPANPPVLPAPQKADTDPENLPEISSQKTQRHIQRGPPHLQIRPPSQDLKDGTQEEATKRQEAPVDPRPEGDPQRTVISWRGAVIEPEQGTELPSRRAEVPTKPPLPPARTQGTPVHLNYRQKGVIDVFLHAWKGYRKFAWGHDELKPVSRSFSEWFGLGLTLIDALDTMWILGLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSGDSLFLRKAEDFGNRLMPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFLPGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVSTCPRPAWSRPPGHRHGWAVGLRLAPLLVVAVTWIREGRACRSLGVATLQLGGPGIPIPTELHGCGTQSTWRGWAPLIFISQGLSREGLCCGPSIPPV 86 4.6 3 4 4 3 3 0.955 0.922 1.126 4 4 4 - - - 1.001 0.109503425 tr|H0YG20|H0YG20_HUMAN 100 0 gi|13096544|pdb|1FMI|A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase 100 0 sp|Q9UKM7|MA1B1_HUMAN Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens GN=MAN1B1 PE=1 SV=2 100 5.00E-123 B3KXZ1 B3KXZ1_HUMAN cDNA FLJ46392 fis, clone THYMU3002825, highly similar to Endoplasmic reticulummannosyl-oligosaccharide 1,2-alpha-mannosidase (EC3.2.1.113) OS=Homo sapiens PE=2 SV=1 - - - - - - - K01230|1|0.0|1140|hsa:11253|mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113] GO:0030433//ER-associated protein catabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006457//protein folding;GO:0043687//post-translational protein modification;GO:0009311//oligosaccharide metabolic process GO:0005509//calcium ion binding;GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0016021//integral to membrane;GO:0005789//endoplasmic reticulum membrane;GO:0044322//endoplasmic reticulum quality control compartment 686 tr|H0YG54|H0YG54_HUMAN Oligoribonuclease, mitochondrial (Fragment) OS=Homo sapiens GN=REXO2 PE=1 SV=1 30411 XQKGFNSFKMTGLDIEKDQIIEMACLITDSDLNILAEGPNLIIKQPDELLDSMSDWCKEHHGKSGLTKAVKESTITLQQAEYEFLSFVRQQTPPGLCPLAGNSVHEDKKFLDKYMPQFMKHLHYRIIDVSTVKELCRRWYPEEYEFAPKKAASHRALDDISESIKELQFYRNNIFKKKIDEKKRKIIENGENEKTVS 84 24.9 3 9 9 6 6 0.843 0.804 0.643 4 4 4 - - - 0.763333333 0.106020438 tr|H0YG54|H0YG54_HUMAN 100 2.00E-24 gi|149041579|gb|EDL95420.1| REX2, RNA exonuclease 2 homolog (S. cerevisiae), isoform CRA_d [Rattus norvegicus] 98.95 8.00E-100 sp|Q9Y3B8|ORN_HUMAN Oligoribonuclease, mitochondrial OS=Homo sapiens GN=REXO2 PE=1 SV=3 100 1.00E-102 H0YG54 H0YG54_HUMAN Oligoribonuclease, mitochondrial (Fragment) OS=Homo sapiens GN=REXO2 PE=4 SV=1 HI1715 180 2.00E-45 COG1949 Oligoribonuclease (3'->5' exoribonuclease) A RNA processing and modification ; K13288|1|5e-100|363|mcc:695292|oligoribonuclease [EC:3.1.-.-] GO:0009117//nucleotide metabolic process GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity;GO:0016896//exoribonuclease activity, producing 5'-phosphomonoesters GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005739//mitochondrion 687 tr|B3KQF5|B3KQF5_HUMAN cDNA FLJ90381 fis, clone NT2RP2005035, highly similar to Calumenin OS=Homo sapiens PE=2 SV=1 46236 MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKTFDQLTPEESKERLGKIVSKIDGDKDGFVTVDELKDWIKFAQKRWIYEDVERQWKGHDLNEDGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMGKVETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF 1151 42.2 1 70 16 12 5 0.693 0.501 0.697 12 12 12 * - * 0.630333333 0.112023807 tr|B3KQF5|B3KQF5_HUMAN 100 1.00E-122 gi|410952803|ref|XP_003983067.1| PREDICTED: calumenin isoform 3 [Felis catus] 99.37 0 sp|O43852|CALU_HUMAN Calumenin OS=Homo sapiens GN=CALU PE=1 SV=2 100 5.00E-122 F5H879 F5H879_HUMAN Calumenin OS=Homo sapiens GN=CALU PE=4 SV=1 - - - - - - - - GO:0002576//platelet degranulation;GO:0030168//platelet activation GO:0005515//protein binding;GO:0005509//calcium ion binding GO:0005794//Golgi apparatus;GO:0042470//melanosome;GO:0033018//sarcoplasmic reticulum lumen;GO:0005576//extracellular region 688 tr|H3BTL1|H3BTL1_HUMAN Microtubule-associated protein 1 light chain 3 beta, isoform CRA_f OS=Homo sapiens GN=MAP1LC3B PE=3 SV=1 11744 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRYSVTFVS 79 18.7 3 2 2 1 1 0.781 0.421 0.598 2 2 2 - * - 0.6 0.180008333 tr|H3BTL1|H3BTL1_HUMAN 100 4.00E-32 gi|119615802|gb|EAW95396.1| microtubule-associated protein 1 light chain 3 beta, isoform CRA_e [Homo sapiens] >gi|374304594|gb|AEZ06292.1| MAP1LC3B-a [Homo sapiens] 100 7.00E-33 sp|O41515|MLP3B_BOVIN Microtubule-associated proteins 1A/1B light chain 3B OS=Bos taurus GN=MAP1LC3B PE=1 SV=4 100 2.00E-31 F7HWW7 F7HWW7_CALJA Uncharacterized protein OS=Callithrix jacchus GN=LOC100410303 PE=3 SV=1 - - - - - - - K10435|1|4e-33|139|mdo:100018370|microtubule-associated protein 1 light chain GO:0000045//autophagic vacuole assembly;GO:0032092//positive regulation of protein binding GO:0008017//microtubule binding;GO:0019904//protein domain specific binding GO:0005875//microtubule associated complex;GO:0000421//autophagic vacuole membrane;GO:0030424//axon;GO:0005874//microtubule;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0043025//neuronal cell body;GO:0012505//endomembrane system 689 sp|P61970|NTF2_HUMAN Nuclear transport factor 2 OS=Homo sapiens GN=NUTF2 PE=1 SV=1 >tr|A0A024R6Y2|A0A024R6Y2_HUMAN Nuclear transport factor 2, isoform CRA_a OS=Homo sapiens GN=NUTF2 PE=4 SV=1 16770 MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNFG 114 23.6 - 5 5 2 2 0.576 0.751 0.934 3 3 3 - - - 0.753666667 0.179014897 sp|P61970|NTF2_HUMAN 100 2.00E-70 gi|5031985|ref|NP_005787.1| nuclear transport factor 2 [Homo sapiens] >gi|13386032|ref|NP_080808.1| nuclear transport factor 2 [Mus musculus] >gi|56090307|ref|NP_001007630.1| nuclear transport factor 2 [Rattus norvegicus] >gi|83035119|ref|NP_001032713.1| nuclear transport factor 2 [Bos taurus] >gi|48429021|sp|P61972.1|NTF2_RAT RecName: Full=Nuclear transport factor 2; Short=NTF-2 >gi|48429030|sp|P61970.1|NTF2_HUMAN RecName: Full=Nuclear transport factor 2; Short=NTF-2; AltName: Full=Placental protein 15; Short=PP15 >gi|48429031|sp|P61971.1|NTF2_MOUSE RecName: Full=Nuclear transport factor 2; Short=NTF-2 >gi|110815881|sp|Q32KP9.1|NTF2_BOVIN RecName: Full=Nuclear transport factor 2; Short=NTF-2 >gi|2098467|pdb|1OUN|A Chain A, Crystal Structure Of Nuclear Transport Factor 2 (Ntf2) >gi|2098468|pdb|1OUN|B Chain B, Crystal Structure Of Nuclear Transport Factor 2 (Ntf2) >gi|3212260|pdb|1A2K|A Chain A, Gdpran-Ntf2 Complex >gi|3212261|pdb|1A2K|B Chain B, Gdpran-Ntf2 Complex >gi|21730275|pdb|1GY6|A Chain A, Ntf2 From Rat, Ammonium Sulphate Conditions >gi|21730276|pdb|1GY6|B Chain B, Ntf2 From Rat, Ammonium Sulphate Conditions >gi|1041643|emb|CAA62839.1| nuclear transport factor 2 [Rattus norvegicus] >gi|1167984|gb|AAA85905.1| nuclear transport factor 2 [Homo sapiens] >gi|12803089|gb|AAH02348.1| Nuclear transport factor 2 [Homo sapiens] >gi|13278247|gb|AAH03955.1| Nuclear transport factor 2 [Mus musculus] >gi|38181567|gb|AAH61569.1| Nuclear transport factor 2 [Rattus norvegicus] >gi|48145991|emb|CAG33218.1| NUTF2 [Homo sapiens] >gi|52789382|gb|AAH83165.1| Nuclear transport factor 2 [Mus musculus] >gi|56270550|gb|AAH86773.1| Nuclear transport factor 2 [Mus musculus] >gi|81673715|gb|AAI09984.1| Nuclear transport factor 2 [Bos taurus] >gi|119603587|gb|EAW83181.1| nuclear transport factor 2, isoform CRA_a [Homo sapiens] >gi|119603588|gb|EAW83182.1| nuclear transport factor 2, isoform CRA_a [Homo sapiens] >gi|148679373|gb|EDL11320.1| mCG20468, isoform CRA_a [Mus musculus] >gi|148679374|gb|EDL11321.1| mCG20468, isoform CRA_a [Mus musculus] >gi|148679375|gb|EDL11322.1| mCG20468, isoform CRA_a [Mus musculus] >gi|148679376|gb|EDL11323.1| mCG20468, isoform CRA_a [Mus musculus] >gi|149038049|gb|EDL92409.1| rCG51595, isoform CRA_a [Rattus norvegicus] >gi|149038050|gb|EDL92410.1| rCG51595, isoform CRA_a [Rattus norvegicus] >gi|149038051|gb|EDL92411.1| rCG51595, isoform CRA_a [Rattus norvegicus] >gi|149038052|gb|EDL92412.1| rCG51595, isoform CRA_a [Rattus norvegicus] >gi|296478022|tpg|DAA20137.1| TPA: nuclear transport factor 2 [Bos taurus] >gi|344254005|gb|EGW10109.1| Nuclear transport factor 2 [Cricetulus griseus] >gi|431912384|gb|ELK14518.1| Nuclear transport factor 2 [Pteropus alecto] >gi|440905431|gb|ELR55808.1| Nuclear transport factor 2 [Bos grunniens mutus] >gi|444709325|gb|ELW50346.1| Nuclear transport factor 2 [Tupaia chinensis] 100 2.00E-71 sp|Q32KP9|NTF2_BOVIN Nuclear transport factor 2 OS=Bos taurus GN=NUTF2 PE=2 SV=1 100 7.00E-70 H2QBC9 H2QBC9_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000102898 PE=4 SV=1 - - - - - - - K14285|1|1e-12|71.2|dmo:Dmoj_GI16389|NTF2-related export protein 1/2 GO:0006606//protein import into nucleus;GO:0006611//protein export from nucleus GO:0005515//protein binding;GO:0008565//protein transporter activity GO:0005643//nuclear pore;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton 690 tr|A0A024R462|A0A024R462_HUMAN Fibronectin 1, isoform CRA_n OS=Homo sapiens GN=FN1 PE=4 SV=1 286673 MLRGPGPGLLLLAVLCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMIWDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHMLNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 22121 41.5 - 998 819 65 57 1.63 1.634 1.552 560 554 553 - - - 1.605333333 0.046231303 tr|A0A024R462|A0A024R462_HUMAN 100 0 gi|119590938|gb|EAW70532.1| fibronectin 1, isoform CRA_c [Homo sapiens] 98.61 0 sp|P02751|FINC_HUMAN Fibronectin OS=Homo sapiens GN=FN1 PE=1 SV=4 100 1.00E-86 Q9H382 Q9H382_HUMAN Fibronectin 1 OS=Homo sapiens PE=2 SV=1 - - - - - - - K05717|1|0.0|4460|hsa:2335|fibronectin 1 GO:0001525//angiogenesis;GO:0010952//positive regulation of peptidase activity;GO:0008360//regulation of cell shape;GO:0030168//platelet activation;GO:0007161//calcium-independent cell-matrix adhesion;GO:0030198//extracellular matrix organization;GO:0034446//substrate adhesion-dependent cell spreading;GO:0050900//leukocyte migration;GO:0007044//cell-substrate junction assembly;GO:0006953//acute-phase response;GO:0018149//peptide cross-linking;GO:0002576//platelet degranulation GO:0016504//peptidase activator activity;GO:0045340//mercury ion binding;GO:0005201//extracellular matrix structural constituent;GO:0008201//heparin binding;GO:0002020//protease binding;GO:0005518//collagen binding GO:0005604//basement membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031093//platelet alpha granule lumen;GO:0005577//fibrinogen complex;GO:0016324//apical plasma membrane 691 tr|B4DGT0|B4DGT0_HUMAN cDNA FLJ54083, highly similar to NG,NG-dimethylarginine dimethylaminohydrolase 1 (EC 3.5.3.18) OS=Homo sapiens PE=2 SV=1 26738 MWLYGLGQVDMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS 122 16.7 3 9 5 3 2 2.204 1.193 1.731 5 5 5 - - - 1.709333333 0.505848133 tr|B4DGT0|B4DGT0_HUMAN 100 3.00E-103 gi|197313763|ref|NP_001127917.1| N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 isoform 2 [Homo sapiens] >gi|119593605|gb|EAW73199.1| dimethylarginine dimethylaminohydrolase 1, isoform CRA_a [Homo sapiens] 99.46 7.00E-106 sp|O94760|DDAH1_HUMAN N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 OS=Homo sapiens GN=DDAH1 PE=1 SV=3 100 5.00E-104 B4DYP1 B4DYP1_HUMAN N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 OS=Homo sapiens GN=DDAH1 PE=2 SV=1 PA1195 64.3 1.00E-10 COG1834 N-Dimethylarginine dimethylaminohydrolase E Amino acid transport and metabolism ; K01482|1|8e-106|382|mcc:711395|dimethylargininase [EC:3.5.3.18] GO:0006527//arginine catabolic process;GO:0045766//positive regulation of angiogenesis;GO:0007263//nitric oxide mediated signal transduction;GO:0000052//citrulline metabolic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0003073//regulation of systemic arterial blood pressure GO:0046872//metal ion binding;GO:0016597//amino acid binding;GO:0016403//dimethylargininase activity GO:0005739//mitochondrion 692 tr|Q5T9B7|Q5T9B7_HUMAN Adenylate kinase isoenzyme 1 OS=Homo sapiens GN=AK1 PE=1 SV=1 29708 MGCCSSSDPRREDDLRAREKLKKTKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK 161 10 2 8 8 2 2 0.729 0.813 0.607 4 4 4 * - * 0.716333333 0.103582495 tr|Q5T9B7|Q5T9B7_HUMAN 100 7.00E-107 gi|4502011|ref|NP_000467.1| adenylate kinase isoenzyme 1 [Homo sapiens] >gi|20178288|sp|P00568.3|KAD1_HUMAN RecName: Full=Adenylate kinase isoenzyme 1; Short=AK 1; AltName: Full=ATP-AMP transphosphorylase 1; AltName: Full=Myokinase >gi|178322|gb|AAA51686.1| adenylate kinase [Homo sapiens] >gi|4996565|dbj|BAA78534.1| adenylate kinase 1 [Homo sapiens] >gi|49456909|emb|CAG46775.1| AK1 [Homo sapiens] >gi|49456961|emb|CAG46801.1| AK1 [Homo sapiens] >gi|54696030|gb|AAV38387.1| adenylate kinase 1 [Homo sapiens] >gi|71679687|gb|AAI00023.1| Adenylate kinase 1 [Homo sapiens] >gi|119608113|gb|EAW87707.1| adenylate kinase 1, isoform CRA_b [Homo sapiens] >gi|119608115|gb|EAW87709.1| adenylate kinase 1, isoform CRA_b [Homo sapiens] 100 9.00E-108 sp|P00568|KAD1_HUMAN Adenylate kinase isoenzyme 1 OS=Homo sapiens GN=AK1 PE=1 SV=3 100 8.00E-118 Q5T9B7 Q5T9B7_HUMAN Adenylate kinase 1 OS=Homo sapiens GN=AK1 PE=2 SV=1 YKL024c 168 5.00E-42 COG0563 Adenylate kinase and related kinases F Nucleotide transport and metabolism ; K00939|1|2e-110|398|cfa:480712|adenylate kinase [EC:2.7.4.3] GO:0007050//cell cycle arrest;GO:0046034//ATP metabolic process;GO:0009165//nucleotide biosynthetic process;GO:0016310//phosphorylation GO:0004017//adenylate kinase activity;GO:0005524//ATP binding GO:0005737//cytoplasm;GO:0005886//plasma membrane 693 tr|Q6FI03|Q6FI03_HUMAN G3BP protein OS=Homo sapiens GN=G3BP PE=2 SV=1 58577 MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNDNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEPEERQQTPEVVPDDSGTFYDQAVVSNDMEEHLEEPVAEPEPDPEPKPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPADIAQTVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQRDQRVREQRINIPPQRGPRPIREAGEQGDIEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQSYGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGLGGGMRGPPRGGMVQKPGFGVGRGLAPRQ 144 3.6 4 4 4 1 1 1.137 1.575 0.851 3 4 4 - * * 1.187666667 0.364649604 tr|Q6FI03|Q6FI03_HUMAN 100 0 gi|49168554|emb|CAG38772.1| G3BP [Homo sapiens] 99.57 0 sp|Q13283|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens GN=G3BP1 PE=1 SV=1 100 0 Q6FI03 Q6FI03_HUMAN G3BP protein OS=Homo sapiens GN=G3BP PE=2 SV=1 - - - - - - - K12741|1|1e-07|58.5|smm:Smp_053940.1|heterogeneous nuclear ribonucleoprotein A1/A3!K13044|5|2e-06|54.7|rno:83498|heterogeneous nuclear ribonucleoprotein A/B/D GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006810//transport;GO:0007265//Ras protein signal transduction GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0004519//endonuclease activity;GO:0004003//ATP-dependent DNA helicase activity;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0005515//protein binding GO:0005829//cytosol;GO:0005634//nucleus;GO:0005886//plasma membrane 694 tr|A0A087X253|A0A087X253_HUMAN AP-2 complex subunit beta OS=Homo sapiens GN=AP2B1 PE=1 SV=1 119901 MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGGGIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN 138 5.7 8 10 7 5 3 0.77 0.853 0.772 2 2 2 * - - 0.798333333 0.047353282 tr|A0A087X253|A0A087X253_HUMAN 100 0 gi|410051547|ref|XP_003953114.1| PREDICTED: AP-1 complex subunit beta-1 [Pan troglodytes] 95.9 0 sp|Q08DS7|AP1B1_BOVIN AP-1 complex subunit beta-1 OS=Bos taurus GN=AP2B1 PE=2 SV=1 100 0 F5GYG9 F5GYG9_HUMAN AP-2 complex subunit beta OS=Homo sapiens GN=AP2B1 PE=4 SV=1 SPBC947.02 495 2.00E-139 COG5096 Vesicle coat complex, various subunits U Intracellular trafficking, secretion, and vesicular transport ; K11825|1|0.0|1711|rno:140670|AP-2 complex subunit beta-1 GO:0007411//axon guidance;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0048268//clathrin coat assembly;GO:0016032//viral reproduction;GO:0007269//neurotransmitter secretion;GO:0006886//intracellular protein transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050690//regulation of defense response to virus by virus;GO:0048488//synaptic vesicle endocytosis GO:0008565//protein transporter activity;GO:0030276//clathrin binding;GO:0032403//protein complex binding GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0005802//trans-Golgi network;GO:0030131//clathrin adaptor complex;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005905//coated pit;GO:0005886//plasma membrane 695 tr|Q53F48|Q53F48_HUMAN Heterogeneous nuclear ribonucleoprotein H3 isoform a variant (Fragment) OS=Homo sapiens PE=2 SV=1 40001 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIKLFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY 67 5.8 1 3 3 2 2 0.836 0.831 0.547 2 2 2 - - * 0.738 0.165429743 tr|Q53F48|Q53F48_HUMAN 100 4.00E-53 gi|14141159|ref|NP_067676.2| heterogeneous nuclear ribonucleoprotein H3 isoform b [Homo sapiens] >gi|7739443|gb|AAF68849.1|AF132361_1 hnRNP 2H9A [Homo sapiens] >gi|7739440|gb|AAF68847.1| hnRNP 2H9A [Homo sapiens] >gi|24981041|gb|AAH39824.1| Heterogeneous nuclear ribonucleoprotein H3 (2H9) [Homo sapiens] >gi|119574667|gb|EAW54282.1| heterogeneous nuclear ribonucleoprotein H3 (2H9), isoform CRA_c [Homo sapiens] >gi|296472170|tpg|DAA14285.1| TPA: heterogeneous nuclear ribonucleoprotein H3 (2H9) [Bos taurus] 100 4.00E-54 sp|P31942|HNRH3_HUMAN Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens GN=HNRNPH3 PE=1 SV=2 100 1.00E-52 D4ABK7 D4ABK7_RAT Heterogeneous nuclear ribonucleoprotein H3 (2H9) (Predicted), isoform CRA_c OS=Rattus norvegicus GN=Hnrnph3 PE=4 SV=1 - - - - - - - K12898|1|4e-54|212|ecb:100063127|heterogeneous nuclear ribonucleoprotein F/H GO:0000398//mRNA splicing, via spliceosome GO:0003723//RNA binding;GO:0000166//nucleotide binding GO:0005730//nucleolus;GO:0030529//ribonucleoprotein complex 696 tr|B4DLB8|B4DLB8_HUMAN cDNA FLJ52205, highly similar to Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) OS=Homo sapiens PE=2 SV=1 43920 MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSSPVVDSGPGPASNLTSVPVPHTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAIIIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALKDYDYTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLTINGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIAHTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS 221 8.7 3 8 8 3 3 1.199 0.903 1.368 7 7 7 - - * 1.156666667 0.235372754 tr|B4DLB8|B4DLB8_HUMAN 100 2.00E-82 gi|194387148|dbj|BAG59940.1| unnamed protein product [Homo sapiens] 92.45 9.00E-21 sp|P08037|B4GT1_BOVIN Beta-1,4-galactosyltransferase 1 OS=Bos taurus GN=B4GALT1 PE=1 SV=3 100 6.00E-82 B4DMM8 B4DMM8_HUMAN Processed beta-1,4-galactosyltransferase 1 OS=Homo sapiens GN=B4GALT1 PE=2 SV=1 - - - - - - - K07966|1|0.0|678|pon:100438031|beta-1,4-galactosyltransferase 1 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-] GO:0060055//angiogenesis involved in wound healing;GO:0060046//regulation of acrosome reaction;GO:0007219//Notch signaling pathway;GO:0051270//regulation of cellular component movement;GO:0007155//cell adhesion;GO:0002526//acute inflammatory response;GO:0005989//lactose biosynthetic process;GO:0030198//extracellular matrix organization;GO:0050900//leukocyte migration;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0008285//negative regulation of cell proliferation;GO:0045136//development of secondary sexual characteristics;GO:0018146//keratan sulfate biosynthetic process;GO:0007339//binding of sperm to zona pellucida;GO:0048754//branching morphogenesis of an epithelial tube;GO:0044281//small molecule metabolic process;GO:0043687//post-translational protein modification;GO:0060058//positive regulation of apoptotic process involved in mammary gland involution;GO:0007341//penetration of zona pellucida;GO:0006012//galactose metabolic process;GO:0002064//epithelial cell development;GO:0018279//protein N-linked glycosylation via asparagine GO:0003831//beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0003945//N-acetyllactosamine synthase activity;GO:0046872//metal ion binding;GO:0043014//alpha-tubulin binding;GO:0004461//lactose synthase activity;GO:0042803//protein homodimerization activity;GO:0048487//beta-tubulin binding GO:0030112//glycocalyx;GO:0031526//brush border membrane;GO:0016323//basolateral plasma membrane;GO:0016021//integral to membrane;GO:0005576//extracellular region;GO:0030057//desmosome;GO:0009897//external side of plasma membrane;GO:0032580//Golgi cisterna membrane;GO:0000138//Golgi trans cisterna 697 tr|E5RHG6|E5RHG6_HUMAN Tubulin-specific chaperone A OS=Homo sapiens GN=TBCA PE=1 SV=2 19673 MADPRVRQIKIKTGVVKRLVKEKVMYEKEAKQQEEKIEKMRAEDGENYDIKKQAGLQLLASSDPPTPASQSPGMISAEILQESRMMIPDCQRRLEAAYLDLQRILENEKDLEEAEEYKEARLVLDSVKLEA 242 19.8 3 8 8 2 2 0.618 1.196 0.717 7 7 7 * - * 0.843666667 0.30911864 tr|E5RHG6|E5RHG6_HUMAN 99.24 1.00E-49 gi|397482984|ref|XP_003812689.1| PREDICTED: tubulin-specific chaperone A isoform 2 [Pan paniscus] 82.44 2.00E-32 sp|O75347|TBCA_HUMAN Tubulin-specific chaperone A OS=Homo sapiens GN=TBCA PE=1 SV=3 98.25 3.00E-15 E5RHG6 E5RHG6_HUMAN Tubulin-specific chaperone A OS=Homo sapiens GN=TBCA PE=4 SV=1 - - - - - - - - GO:0006457//protein folding;GO:0072668//tubulin complex biogenesis GO:0005515//protein binding GO:0005730//nucleolus;GO:0015630//microtubule cytoskeleton 698 tr|M0R210|M0R210_HUMAN 40S ribosomal protein S16 OS=Homo sapiens GN=RPS16 PE=1 SV=1 19391 MPSKGPLQSVQVFGRKKTATAVAHCKRGNGLIKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR 123 16.3 3 5 5 2 2 1.267 0.809 0.664 3 4 3 - - - 0.913333333 0.314748047 tr|M0R210|M0R210_HUMAN 100 7.00E-31 gi|45269027|gb|AAS55926.1| 40S ribosomal protein S16, partial [Sus scrofa] 88.36 4.00E-66 sp|Q3T0X6|RS16_BOVIN 40S ribosomal protein S16 OS=Bos taurus GN=RPS16 PE=2 SV=3 100 4.00E-48 G3HJD8 G3HJD8_CRIGR 40S ribosomal protein S16 OS=Cricetulus griseus GN=I79_010782 PE=3 SV=1 SPBC18H10.14 179 1.00E-45 COG0103 Ribosomal protein S9 J Translation, ribosomal structure and biogenesis ; K02960|1|2e-69|259|ptr:456023|small subunit ribosomal protein S16e GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006364//rRNA processing;GO:0006414//translational elongation;GO:0042274//ribosomal small subunit biogenesis;GO:0006415//translational termination;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome GO:0022627//cytosolic small ribosomal subunit 699 sp|P18065|IBP2_HUMAN Insulin-like growth factor-binding protein 2 OS=Homo sapiens GN=IGFBP2 PE=1 SV=2 40133 MLPRVGCPALPLPPPPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQEARGVHTQRMQ 3825 28 - 113 113 7 7 0.598 0.66 0.685 89 92 87 - - * 0.647666667 0.044792112 sp|P18065|IBP2_HUMAN 100 2.00E-144 gi|119590979|gb|EAW70573.1| insulin-like growth factor binding protein 2, 36kDa [Homo sapiens] 100 4.00E-154 sp|P18065|IBP2_HUMAN Insulin-like growth factor-binding protein 2 OS=Homo sapiens GN=IGFBP2 PE=1 SV=2 100 3.00E-117 G3R7T3 G3R7T3_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=IGFBP2 PE=4 SV=1 - - - - - - - K10138|1|2e-28|126|rno:24484|insulin-like growth factor-binding protein 3 GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0001558//regulation of cell growth;GO:0007565//female pregnancy;GO:0051384//response to glucocorticoid stimulus;GO:0042104//positive regulation of activated T cell proliferation;GO:0032870//cellular response to hormone stimulus;GO:0007568//aging;GO:0045927//positive regulation of growth;GO:0032526//response to retinoic acid;GO:0032355//response to estradiol stimulus;GO:0042493//response to drug;GO:0010226//response to lithium ion;GO:0006950//response to stress;GO:0009612//response to mechanical stimulus GO:0031994//insulin-like growth factor I binding;GO:0031995//insulin-like growth factor II binding GO:0005615//extracellular space;GO:0031410//cytoplasmic vesicle;GO:0016324//apical plasma membrane 700 tr|B2R5M8|B2R5M8_HUMAN Isocitrate dehydrogenase [NADP] OS=Homo sapiens PE=2 SV=1 58464 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFSYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 105 17.4 3 15 15 7 7 1.274 2.054 1 4 4 4 - * - 1.442666667 0.546868662 tr|B2R5M8|B2R5M8_HUMAN 100 0 gi|189053370|dbj|BAG35175.1| unnamed protein product [Homo sapiens] 99.76 0 sp|O75874|IDHC_HUMAN Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens GN=IDH1 PE=1 SV=2 100 0 B2R5M8 B2R5M8_HUMAN Isocitrate dehydrogenase [NADP] OS=Homo sapiens PE=2 SV=1 SMc00480 580 2.00E-165 COG0538 Isocitrate dehydrogenases C Energy production and conversion ; K00031|1|0.0|864|hsa:3417|isocitrate dehydrogenase [EC:1.1.1.42] GO:0006979//response to oxidative stress;GO:0006097//glyoxylate cycle;GO:0006103//2-oxoglutarate metabolic process;GO:0006749//glutathione metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0006740//NADPH regeneration;GO:0006102//isocitrate metabolic process;GO:0044255//cellular lipid metabolic process GO:0051287//NAD binding;GO:0005102//receptor binding;GO:0004450//isocitrate dehydrogenase (NADP+) activity;GO:0000287//magnesium ion binding;GO:0042803//protein homodimerization activity GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005782//peroxisomal matrix 701 sp|Q13308|PTK7_HUMAN Inactive tyrosine-protein kinase 7 OS=Homo sapiens GN=PTK7 PE=1 SV=2 135618 MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSKP 524 13.7 - 20 20 10 10 1.017 0.911 0.947 14 13 13 - - - 0.958333333 0.053901144 sp|Q13308|PTK7_HUMAN 100 2.00E-56 gi|7018530|emb|CAB75674.1| hypothetical protein [Homo sapiens] 100 0 sp|Q13308|PTK7_HUMAN Inactive tyrosine-protein kinase 7 OS=Homo sapiens GN=PTK7 PE=1 SV=2 100 0 B7Z471 B7Z471_HUMAN Inactive tyrosine-protein kinase 7 OS=Homo sapiens GN=PTK7 PE=2 SV=1 BH2504_1 99.8 3.00E-20 COG0515 Serine/threonine protein kinase RTKL General function prediction only ; Signal transduction mechanisms ; Transcription ; Replication, recombination and repair ; K05127|1|0.0|2140|hsa:5754|PTK7 protein tyrosine kinase 7 [EC:2.7.10.1] GO:0060070//canonical Wnt receptor signaling pathway;GO:0003401//axis elongation;GO:0060026//convergent extension;GO:0007155//cell adhesion;GO:0060484//lung-associated mesenchyme development;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0042060//wound healing;GO:0090103//cochlea morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0010976//positive regulation of neuron projection development;GO:0031532//actin cytoskeleton reorganization;GO:0016477//cell migration GO:0005515//protein binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005524//ATP binding GO:0005911//cell-cell junction;GO:0005887//integral to plasma membrane 702 tr|Q5CAQ5|Q5CAQ5_HUMAN Tumor rejection antigen (Gp96) 1 OS=Homo sapiens GN=TRA1 PE=2 SV=1 116600 MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEETAKESTAEKDEL 647 17.3 1 43 36 13 12 1.238 0.983 1.457 18 18 17 * - * 1.226 0.237227739 tr|Q5CAQ5|Q5CAQ5_HUMAN 100 0 gi|4507677|ref|NP_003290.1| endoplasmin precursor [Homo sapiens] >gi|119360|sp|P14625.1|ENPL_HUMAN RecName: Full=Endoplasmin; AltName: Full=94 kDa glucose-regulated protein; Short=GRP-94; AltName: Full=Heat shock protein 90 kDa beta member 1; AltName: Full=Tumor rejection antigen 1; AltName: Full=gp96 homolog; Flags: Precursor >gi|37261|emb|CAA33261.1| precursor polypeptide (AA-21 to 782) [Homo sapiens] >gi|44890631|gb|AAH66656.1| Heat shock protein 90kDa beta (Grp94), member 1 [Homo sapiens] >gi|119618130|gb|EAW97724.1| heat shock protein 90kDa beta (Grp94), member 1, isoform CRA_b [Homo sapiens] 100 0 sp|Q4R520|ENPL_MACFA Endoplasmin OS=Macaca fascicularis GN=HSP90B1 PE=2 SV=1 100 0 F7EZT6 F7EZT6_MACMU Endoplasmin OS=Macaca mulatta GN=Mmu.1931 PE=2 SV=1 SPAC926.04c 625 1.00E-178 COG0326 Molecular chaperone, HSP90 family O Posttranslational modification, protein turnover, chaperones ; K09487|1|0.0|1378|mcc:699568|heat shock protein 90kDa beta GO:0030433//ER-associated protein catabolic process;GO:0006457//protein folding;GO:0031247//actin rod assembly;GO:0015031//protein transport;GO:0001666//response to hypoxia;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0051208//sequestering of calcium ion;GO:0071318//cellular response to ATP;GO:0045087//innate immune response;GO:0043666//regulation of phosphoprotein phosphatase activity GO:0046790//virion binding;GO:0005509//calcium ion binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0051082//unfolded protein binding;GO:0019903//protein phosphatase binding;GO:0003723//RNA binding;GO:0005524//ATP binding GO:0005788//endoplasmic reticulum lumen;GO:0042470//melanosome;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0030496//midbody;GO:0048471//perinuclear region of cytoplasm;GO:0044459//plasma membrane part 703 sp|P50454|SERPH_HUMAN Serpin H1 OS=Homo sapiens GN=SERPINH1 PE=1 SV=2 >tr|A0A024R5K8|A0A024R5K8_HUMAN Serpin peptidase inhibitor, clade H (Heat shock protein 47), member 1, (Collagen binding protein 1), isoform CRA_a OS=Homo sapiens GN=SERPINH1 PE=3 SV=1 57172 MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL 827 34 - 38 38 12 12 1.286 1.545 1.154 24 25 25 * * * 1.328333333 0.198907851 sp|P50454|SERPH_HUMAN 100 0 gi|332211278|ref|XP_003254748.1| PREDICTED: serpin H1 isoform 1 [Nomascus leucogenys] >gi|332211280|ref|XP_003254749.1| PREDICTED: serpin H1 isoform 2 [Nomascus leucogenys] 100 0 sp|P50454|SERPH_HUMAN Serpin H1 OS=Homo sapiens GN=SERPINH1 PE=1 SV=2 100 4.00E-54 E9PIG2 E9PIG2_HUMAN Serpin H1 OS=Homo sapiens GN=SERPINH1 PE=4 SV=1 all0778 145 2.00E-34 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K09501|1|0.0|750|ptr:466899|serpin peptidase inhibitor, clade H, member 1 GO:0010951//negative regulation of endopeptidase activity;GO:0051604//protein maturation;GO:0030199//collagen fibril organization;GO:0030162//regulation of proteolysis;GO:0006986//response to unfolded protein;GO:0032964//collagen biosynthetic process GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005518//collagen binding;GO:0051082//unfolded protein binding GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005788//endoplasmic reticulum lumen 704 tr|Q5JPE4|Q5JPE4_HUMAN Putative uncharacterized protein DKFZp667O202 OS=Homo sapiens GN=DKFZp667O202 PE=4 SV=1 24810 MVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKP 46 11 2 4 4 2 2 1.891 1.307 0.539 2 2 2 - * - 1.245666667 0.678083574 tr|Q5JPE4|Q5JPE4_HUMAN 100 3.00E-44 gi|116283479|gb|AAH15095.1| VPS29 protein [Homo sapiens] 99.45 1.00E-103 sp|Q9UBQ0|VPS29_HUMAN Vacuolar protein sorting-associated protein 29 OS=Homo sapiens GN=VPS29 PE=1 SV=1 100 9.00E-44 Q05DG7 Q05DG7_HUMAN VPS29 protein OS=Homo sapiens GN=VPS29 PE=2 SV=1 SPAC15E1.06 184 8.00E-47 COG0622 Predicted phosphoesterase R General function prediction only ; K07095|1|1e-103|375|hsa:51699| GO:0006896//Golgi to vacuole transport;GO:0015031//protein transport GO:0046872//metal ion binding;GO:0004647//phosphoserine phosphatase activity GO:0010008//endosome membrane 705 tr|Q6LET3|Q6LET3_HUMAN HPRT1 protein (Fragment) OS=Homo sapiens GN=HPRT1 PE=2 SV=1 29972 MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRHYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA 85 6 1 2 2 1 1 0.905 0.743 1.278 2 2 2 - - - 0.975333333 0.274347104 tr|Q6LET3|Q6LET3_HUMAN 100 2.00E-124 gi|47115227|emb|CAG28573.1| HPRT1 [Homo sapiens] 99.54 1.00E-124 sp|P00492|HPRT_HUMAN Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens GN=HPRT1 PE=1 SV=2 100 8.00E-124 Q6LET3 Q6LET3_HUMAN HPRT1 protein (Fragment) OS=Homo sapiens GN=HPRT1 PE=2 SV=1 lin0251_2 114 1.00E-25 COG0634 Hypoxanthine-guanine phosphoribosyltransferase F Nucleotide transport and metabolism ; K00760|1|2e-124|444|pon:100447935|hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] GO:0019835//cytolysis;GO:0046038//GMP catabolic process;GO:0006168//adenine salvage;GO:0045964//positive regulation of dopamine metabolic process;GO:0051289//protein homotetramerization;GO:0001975//response to amphetamine;GO:0021954//central nervous system neuron development;GO:0006178//guanine salvage;GO:0007625//grooming behavior;GO:0021895//cerebral cortex neuron differentiation;GO:0021756//striatum development;GO:0048813//dendrite morphogenesis;GO:0032263//GMP salvage;GO:0007283//spermatogenesis;GO:0046651//lymphocyte proliferation;GO:0032264//IMP salvage;GO:0043103//hypoxanthine salvage;GO:0006166//purine ribonucleoside salvage GO:0000166//nucleotide binding;GO:0004422//hypoxanthine phosphoribosyltransferase activity;GO:0000287//magnesium ion binding;GO:0052657//guanine phosphoribosyltransferase activity;GO:0042803//protein homodimerization activity GO:0005829//cytosol 706 tr|A0A024R1Y2|A0A024R1Y2_HUMAN ATP citrate lyase, isoform CRA_a OS=Homo sapiens GN=ACLY PE=4 SV=1 142815 MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPDQLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFYVCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEILASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPPPFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNELANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRAIRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALGHRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPNLILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRHPWDDISYVLPEHMSM 255 6.4 2 13 13 6 6 0.557 0.414 0.52 8 8 7 * - * 0.497 0.074222638 tr|A0A024R1Y2|A0A024R1Y2_HUMAN 100 1.00E-48 gi|194388336|dbj|BAG65552.1| unnamed protein product [Homo sapiens] 98.91 0 sp|P53396|ACLY_HUMAN ATP-citrate synthase OS=Homo sapiens GN=ACLY PE=1 SV=3 100 0 Q8N9C4 Q8N9C4_HUMAN cDNA FLJ37765 fis, clone BRHIP2024742, highly similar to ATP-CITRATE OS=Homo sapiens PE=2 SV=1 SPBC1703.07_1 524 3.00E-148 COG0074 Succinyl-CoA synthetase, alpha subunit C Energy production and conversion ; K01648|1|0.0|2189|hsa:47|ATP citrate (pro-S)-lyase [EC:2.3.3.8] GO:0031325//positive regulation of cellular metabolic process;GO:0006101//citrate metabolic process;GO:0015936//coenzyme A metabolic process;GO:0006112//energy reserve metabolic process;GO:0044262//cellular carbohydrate metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0006200//ATP catabolic process;GO:0006085//acetyl-CoA biosynthetic process GO:0048037//cofactor binding;GO:0005515//protein binding;GO:0003878//ATP citrate synthase activity;GO:0046872//metal ion binding;GO:0016829//lyase activity;GO:0005524//ATP binding;GO:0004775//succinate-CoA ligase (ADP-forming) activity GO:0005730//nucleolus;GO:0005829//cytosol;GO:0009346//citrate lyase complex;GO:0005886//plasma membrane;GO:0005739//mitochondrion 707 tr|Q6PIX2|Q6PIX2_HUMAN SFPQ protein (Fragment) OS=Homo sapiens GN=SFPQ PE=2 SV=1 66197 MSRDRFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLKKKKKK 58 5.3 3 3 3 3 3 1.077 0.922 --- 2 2 1 - - - 0.9995 0.109601551 tr|Q6PIX2|Q6PIX2_HUMAN 100 6.00E-141 gi|329664922|ref|NP_001193220.1| splicing factor, proline- and glutamine-rich [Bos taurus] >gi|296489006|tpg|DAA31119.1| TPA: splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) [Bos taurus] 100 5.00E-142 sp|P23246|SFPQ_HUMAN Splicing factor, proline- and glutamine-rich OS=Homo sapiens GN=SFPQ PE=1 SV=2 100 3.00E-132 G1L1Y0 G1L1Y0_AILME Uncharacterized protein (Fragment) OS=Ailuropoda melanoleuca PE=4 SV=1 TP0356 54.3 6.00E-07 COG0724 RNA-binding proteins (RRM domain) R General function prediction only ; K13219|1|5e-142|504|pon:100445899|splicing factor, proline- and glutamine-rich GO:0006310//DNA recombination;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-dependent;GO:0000380//alternative mRNA splicing, via spliceosome GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding GO:0042382//paraspeckles;GO:0016363//nuclear matrix;GO:0005737//cytoplasm 708 tr|Q53FB0|Q53FB0_HUMAN Chloride intracellular channel 1 variant (Fragment) OS=Homo sapiens PE=2 SV=1 33120 MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKYLKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK 584 39.4 1 28 28 7 7 0.753 0.508 0.661 14 17 15 * * * 0.640666667 0.123759175 tr|Q53FB0|Q53FB0_HUMAN 100 2.00E-139 gi|62898319|dbj|BAD97099.1| chloride intracellular channel 1 variant [Homo sapiens] 100 4.00E-60 sp|Q29238|CLIC1_PIG Chloride intracellular channel protein 1 (Fragment) OS=Sus scrofa GN=CLIC1 PE=3 SV=2 100 7.00E-139 Q53FB0 Q53FB0_HUMAN Chloride intracellular channel 1 variant (Fragment) OS=Homo sapiens PE=2 SV=1 - - - - - - - K05021|1|2e-139|494|ptr:462564|chloride intracellular channel 1 GO:0034765//regulation of ion transmembrane transport;GO:0045669//positive regulation of osteoblast differentiation;GO:0051881//regulation of mitochondrial membrane potential;GO:0006821//chloride transport;GO:0007165//signal transduction GO:0005247//voltage-gated chloride channel activity;GO:0005515//protein binding GO:0031965//nuclear membrane;GO:0005739//mitochondrion;GO:0005903//brush border;GO:0034707//chloride channel complex;GO:0005886//plasma membrane 709 sp|P41222|PTGDS_HUMAN Prostaglandin-H2 D-isomerase OS=Homo sapiens GN=PTGDS PE=1 SV=1 >tr|A0A024R8G3|A0A024R8G3_HUMAN Prostaglandin D2 synthase 21kDa (Brain), isoform CRA_a OS=Homo sapiens GN=PTGDS PE=3 SV=1 24590 MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCMTEQ 1565 27.9 - 58 58 4 4 1.56 1.384 1.571 36 37 36 * - - 1.505 0.104933312 sp|P41222|PTGDS_HUMAN 100 9.00E-96 gi|283806778|pdb|2WWP|A Chain A, Crystal Structure Of The Human Lipocalin-Type Prostaglandin D Synthase Crystallised With The Substrate Analog 9,11-Dideoxy-9alpha,11alpha-Epoxymethanoprostaglandin F2alpha >gi|283806779|pdb|2WWP|B Chain B, Crystal Structure Of The Human Lipocalin-Type Prostaglandin D Synthase Crystallised With The Substrate Analog 9,11-Dideoxy-9alpha,11alpha-Epoxymethanoprostaglandin F2alpha >gi|469474572|pdb|4IMN|A Chain A, Crystal Structure Of Wild Type Human Lipocalin Pgds Bound With Peg Mme 2000 >gi|469474573|pdb|4IMO|A Chain A, Crystal Structure Of Wild Type Human Lipocalin Pgds In Complex With Substrate Analog U44069 100 3.00E-110 sp|P41222|PTGDS_HUMAN Prostaglandin-H2 D-isomerase OS=Homo sapiens GN=PTGDS PE=1 SV=1 99.35 3.00E-85 H0Y5A1 H0Y5A1_HUMAN Prostaglandin-H2 D-isomerase (Fragment) OS=Homo sapiens GN=PTGDS PE=3 SV=1 - - - - - - - K01830|1|3e-110|397|hsa:5730|prostaglandin-H2 D-isomerase [EC:5.3.99.2] GO:0006810//transport;GO:0001516//prostaglandin biosynthetic process;GO:0051384//response to glucocorticoid stimulus;GO:0045187//regulation of circadian sleep/wake cycle, sleep GO:0005501//retinoid binding;GO:0004667//prostaglandin-D synthase activity;GO:0005215//transporter activity;GO:0036094//small molecule binding;GO:0005504//fatty acid binding GO:0031965//nuclear membrane;GO:0005615//extracellular space;GO:0005791//rough endoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm;GO:0005794//Golgi apparatus 710 tr|Q59FI9|Q59FI9_HUMAN Ribosomal protein L12 variant (Fragment) OS=Homo sapiens PE=2 SV=1 26622 SNCSRLSARRRPRCNFLRSSRIRVHPTPAASTMPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIVRQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS 137 22.3 1 8 8 3 3 1.148 0.676 0.751 5 5 5 - * * 0.858333333 0.253646079 tr|Q59FI9|Q59FI9_HUMAN 100 8.00E-111 gi|62088522|dbj|BAD92708.1| ribosomal protein L12 variant [Homo sapiens] 99.39 1.00E-91 sp|E2RR58|RL12_CANFA 60S ribosomal protein L12 OS=Canis familiaris GN=RPL12 PE=1 SV=1 100 3.00E-110 Q59FI9 Q59FI9_HUMAN Ribosomal protein L12 variant (Fragment) OS=Homo sapiens PE=2 SV=1 SPCC31H12.04c 255 3.00E-68 COG0080 Ribosomal protein L11 J Translation, ribosomal structure and biogenesis ; K02870|1|6e-109|392|ptr:100610471|large subunit ribosomal protein L12e - - 711 tr|J3QLE5|J3QLE5_HUMAN Small nuclear ribonucleoprotein-associated protein N (Fragment) OS=Homo sapiens GN=SNRPN PE=4 SV=1 21053 MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAVAATASIAGAPTQYP 70 5.3 10 7 7 2 2 1.794 1.045 2.148 5 5 4 - - * 1.662333333 0.56316457 tr|J3QLE5|J3QLE5_HUMAN 100 2.00E-25 gi|345316084|ref|XP_001519203.2| PREDICTED: hypothetical protein LOC100089922 [Ornithorhynchus anatinus] 100 3.00E-62 sp|Q5R6I0|RSMN_PONAB Small nuclear ribonucleoprotein-associated protein N OS=Pongo abelii GN=SNRPN PE=2 SV=1 100 3.00E-60 G3QN10 G3QN10_GORGO Small nuclear ribonucleoprotein-associated protein OS=Gorilla gorilla gorilla GN=SNRPN PE=3 SV=1 SPAC26A3.08 124 7.00E-29 COG1958 Small nuclear ribonucleoprotein (snRNP) homolog K Transcription ; K11100|1|5e-63|239|bta:780877|small nuclear ribonucleoprotein N GO:0008380//RNA splicing;GO:0009725//response to hormone stimulus GO:0003676//nucleic acid binding;GO:0005515//protein binding GO:0005685//U1 snRNP;GO:0005686//U2 snRNP;GO:0005681//spliceosomal complex 712 tr|B3KUE5|B3KUE5_HUMAN Phospholipid transfer protein, isoform CRA_c OS=Homo sapiens GN=PLTP PE=2 SV=1 62359 MGLSGSDNSCDPTPPPGPLAMALFGALFLALLAGAHAEFPGCKIRVTSKALELVKQEGLRFLEQELETITIPDLRGKEGHFYYNISEVKVTELQLTSSELDFQPQQELMLQITNASLGLRFRRQLLYWFFYDGGYINASAEGVSIRTGLELSRDPAGRMKVSNVSCQASVSRMHAAFGGTFKKVYDFLSTFITSGMRFLLNQQICPVLYHAGTVLLNSLLDTVPVRSSVDELVGIDYSLMKDPVASTSNLDMDFRGAFFPLTERNWSLPNRAVEPQLQEEERMVYVAFSEFFFDSAMESYFRAGALQLLLVGDKVPHDLDMLLRATYFGSIVLLSPAVIDSPLKLELRVLAPPRCTIKPSGTTISVTASVTIALVPPDQPEVQLSSMTMDARLSAKMALRGKALRTQLDLRRFRIYSNHSALESLALIPLQAPLKTMLQIGVMPMLNERTWRGVQIPLPEGINFVHEVVTNHAGFLTIGADLHFAKGLREVIEKNRPADVRASTAPTPSTAAV 336 9.9 2 22 22 4 4 2.297 1.463 2.108 14 12 13 * * * 1.956 0.437283661 tr|B3KUE5|B3KUE5_HUMAN 100 0 gi|339275810|ref|NP_001229850.1| phospholipid transfer protein isoform d [Homo sapiens] 100 0 sp|P55058|PLTP_HUMAN Phospholipid transfer protein OS=Homo sapiens GN=PLTP PE=1 SV=1 100 5.00E-23 E7EV16 E7EV16_HUMAN Phospholipid transfer protein OS=Homo sapiens GN=PLTP PE=4 SV=1 - - - - - - - K08761|1|0.0|960|hsa:5360|phospholipid transfer protein GO:0010189//vitamin E biosynthetic process;GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0030317//sperm motility GO:0008289//lipid binding GO:0005576//extracellular region 713 tr|B2R950|B2R950_HUMAN cDNA, FLJ94213, highly similar to Homo sapiens pregnancy-zone protein (PZP), mRNA OS=Homo sapiens PE=2 SV=1 187153 MRKDRLLHLCLVLLLILLSASDSNSTEPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVSASLESGRENRSLFTDLVAEKDLFHCVSFTLPRISASSEVAFLSIQIKGPTQDFRKRNTVLVLNTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKLEAGINQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIISIMDEKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEVCEEFSQQLNSNGCITQQVHTKMLQITNTGFEMKLRVEARIREEGTDLEVTANRISEITNIVSKLKFVKVDSHFRQGIPFFAQVLLVDGKGVPIPNKLFFISVNDANYYSNATTNEQGLAQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDLTNFPDNVDQQEEEQGHCPRPFFIHNGAIYVPLSSNEADIYSFLKGMGLKVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYNVIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQNTKGEESYCICGNERQTLSWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAEGIEQEKTFSSMTCASGANVSEQLSLKLPSNVVKESARASFSVLGDILGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLITGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQKDNGCFRSSGSLLNNAIKGGVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLESAWNVAKEGTHGSHVYTKALLAYAFSLLGKQNQNREILNSLDKEAVKEDNLVHWERPQRPKAPVGHLYQPQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKTAQVTVQDSQIFSTNFQVDNNNLLLLQQISLPELPGEYVITVTGERCVYLQTSMKYNILPEKEDSPFALKVQTVPQTCDGHKAHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESVVAEYIAPCSTDTEHGNV 361 2.3 1 38 11 3 1 0.82 0.844 0.546 5 5 5 - - - 0.736666667 0.165557644 tr|B2R950|B2R950_HUMAN 100 0 gi|84627489|gb|AAI11757.1| PZP protein [Homo sapiens] 99.87 0 sp|P20742|PZP_HUMAN Pregnancy zone protein OS=Homo sapiens GN=PZP PE=1 SV=4 100 0 B2R950 B2R950_HUMAN cDNA, FLJ94213, highly similar to Homo sapiens pregnancy-zone protein (PZP), mRNA OS=Homo sapiens PE=2 SV=1 TM0984 80.5 2.00E-14 COG2373 Large extracellular alpha-helical protein R General function prediction only ; K03910|1|0.0|2115|ptr:465372|alpha-2-macroglobulin GO:0030168//platelet activation;GO:0001869//negative regulation of complement activation, lectin pathway;GO:0010951//negative regulation of endopeptidase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007565//female pregnancy;GO:0007597//blood coagulation, intrinsic pathway;GO:0002576//platelet degranulation GO:0019966//interleukin-1 binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0043120//tumor necrosis factor binding;GO:0019959//interleukin-8 binding;GO:0019899//enzyme binding GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005829//cytosol 714 tr|G3V5Z7|G3V5Z7_HUMAN Proteasome subunit alpha type OS=Homo sapiens GN=PSMA6 PE=1 SV=1 34612 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCWSFLFLGMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAERD 246 24.6 1 13 13 5 5 0.869 1.029 0.865 6 7 7 - - - 0.921 0.093552125 tr|G3V5Z7|G3V5Z7_HUMAN 97.22 9.00E-141 gi|8394076|ref|NP_058979.1| proteasome subunit alpha type-6 [Rattus norvegicus] >gi|23110944|ref|NP_002782.1| proteasome subunit alpha type-6 [Homo sapiens] >gi|114053135|ref|NP_001039427.1| proteasome subunit alpha type-6 [Bos taurus] >gi|302148473|ref|NP_001180482.1| proteasome subunit alpha type-6 [Macaca mulatta] >gi|350534662|ref|NP_001233586.1| proteasome subunit alpha type-6 [Pan troglodytes] >gi|46397655|sp|P60901.1|PSA6_RAT RecName: Full=Proteasome subunit alpha type-6; AltName: Full=Macropain iota chain; AltName: Full=Multicatalytic endopeptidase complex iota chain; AltName: Full=Proteasome iota chain >gi|46397659|sp|P60900.1|PSA6_HUMAN RecName: Full=Proteasome subunit alpha type-6; AltName: Full=27 kDa prosomal protein; Short=PROS-27; Short=p27K; AltName: Full=Macropain iota chain; AltName: Full=Multicatalytic endopeptidase complex iota chain; AltName: Full=Proteasome iota chain >gi|122138169|sp|Q2YDE4.1|PSA6_BOVIN RecName: Full=Proteasome subunit alpha type-6 >gi|21465642|pdb|1IRU|A Chain A, Crystal Structure Of The Mammalian 20s Proteasome At 2.75 A Resolution >gi|21465656|pdb|1IRU|O Chain O, Crystal Structure Of The Mammalian 20s Proteasome At 2.75 A Resolution >gi|35682|emb|CAA42052.1| prosomal P27K protein [Homo sapiens] >gi|286250|dbj|BAA01587.1| proteasome subunit R-IOTA [Rattus sp.] >gi|12804241|gb|AAH02979.1| Proteasome (prosome, macropain) subunit, alpha type, 6 [Homo sapiens] >gi|17389730|gb|AAH17882.1| Proteasome (prosome, macropain) subunit, alpha type, 6 [Homo sapiens] >gi|18490853|gb|AAH22354.1| Proteasome (prosome, macropain) subunit, alpha type, 6 [Homo sapiens] >gi|23273861|gb|AAH23659.1| Proteasome (prosome, macropain) subunit, alpha type, 6 [Homo sapiens] >gi|38328367|gb|AAH62232.1| Proteasome (prosome, macropain) subunit, alpha type 6 [Rattus norvegicus] >gi|47125332|gb|AAH70137.1| Proteasome (prosome, macropain) subunit, alpha type, 6 [Homo sapiens] >gi|48146005|emb|CAG33225.1| PSMA6 [Homo sapiens] >gi|82571777|gb|AAI10261.1| Proteasome (prosome, macropain) subunit, alpha type, 6 [Bos taurus] >gi|119586281|gb|EAW65877.1| proteasome (prosome, macropain) subunit, alpha type, 6, isoform CRA_b [Homo sapiens] >gi|149051253|gb|EDM03426.1| proteasome (prosome, macropain) subunit, alpha type 6 [Rattus norvegicus] >gi|222154129|gb|ACM47241.1| proteasome subunit alpha type 6 [Capra hircus] >gi|296475340|tpg|DAA17455.1| TPA: proteasome subunit alpha type-6 [Bos taurus] >gi|343959656|dbj|BAK63685.1| proteasome subunit alpha type 6 [Pan troglodytes] >gi|351700059|gb|EHB02978.1| Proteasome subunit alpha type-6 [Heterocephalus glaber] >gi|431907347|gb|ELK11320.1| Proteasome subunit alpha type-6 [Pteropus alecto] >gi|440909279|gb|ELR59203.1| Proteasome subunit alpha type-6 [Bos grunniens mutus] >gi|446773|prf||1912298A prosomal RNA-binding protein p27K 97.22 1.00E-141 sp|P60900|PSA6_HUMAN Proteasome subunit alpha type-6 OS=Homo sapiens GN=PSMA6 PE=1 SV=1 100 3.00E-147 G3V5Z7 G3V5Z7_HUMAN Proteasome subunit alpha type OS=Homo sapiens GN=PSMA6 PE=3 SV=1 YGL011c 249 3.00E-66 COG0638 20S proteasome, alpha and beta subunits O Posttranslational modification, protein turnover, chaperones ; K02730|1|1e-141|502|ecb:100050805|20S proteasome subunit alpha 1 [EC:3.4.25.1] GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016032//viral reproduction;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0007519//skeletal muscle tissue development;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0050727//regulation of inflammatory response;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0035639//purine ribonucleoside triphosphate binding;GO:0004298//threonine-type endopeptidase activity;GO:0051059//NF-kappaB binding;GO:0003723//RNA binding GO:0005654//nucleoplasm;GO:0005844//polysome;GO:0005829//cytosol;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0016363//nuclear matrix;GO:0030017//sarcomere;GO:0005739//mitochondrion 715 tr|Q8WVW9|Q8WVW9_HUMAN Similar to signal recognition particle 9kD (Fragment) OS=Homo sapiens PE=2 SV=1 7135 VTDDLVCLVYKTDQAQDVKKIEKFHSQLMRLMVAKEARNVTMETE 71 24.4 1 3 3 1 1 1.215 1.017 1.144 2 2 2 - - - 1.125333333 0.100311182 tr|Q8WVW9|Q8WVW9_HUMAN 100 5.00E-18 gi|4507217|ref|NP_003124.1| signal recognition particle 9 kDa protein isoform 2 [Homo sapiens] >gi|350538135|ref|NP_001233507.1| signal recognition particle 9 kDa protein [Pan troglodytes] >gi|1351111|sp|P49458.2|SRP09_HUMAN RecName: Full=Signal recognition particle 9 kDa protein; Short=SRP9 >gi|897851|gb|AAA70170.1| signal recognition particle subunit 9 [Homo sapiens] >gi|14250077|gb|AAH08443.1| Signal recognition particle 9kDa [Homo sapiens] >gi|15929315|gb|AAH15094.1| Signal recognition particle 9kDa [Homo sapiens] >gi|18490251|gb|AAH22415.1| Signal recognition particle 9kDa [Homo sapiens] >gi|44890766|gb|AAH66957.1| Signal recognition particle 9kDa [Homo sapiens] >gi|119570491|gb|EAW50106.1| hCG1781062 [Homo sapiens] >gi|119590156|gb|EAW69750.1| signal recognition particle 9kDa, isoform CRA_a [Homo sapiens] >gi|343960224|dbj|BAK63966.1| signal recognition particle 9 kDa protein [Pan troglodytes] 100 6.00E-19 sp|P49458|SRP09_HUMAN Signal recognition particle 9 kDa protein OS=Homo sapiens GN=SRP9 PE=1 SV=2 100 1.00E-15 H2N3K3 H2N3K3_PONAB Signal recognition particle 9 kDa protein OS=Pongo abelii GN=LOC100438779 PE=3 SV=1 - - - - - - - K03109|1|3e-18|90.5|mmu:27058|signal recognition particle subunit SRP9 GO:0045900//negative regulation of translational elongation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane GO:0008312//7S RNA binding;GO:0005047//signal recognition particle binding GO:0005829//cytosol;GO:0005786//signal recognition particle, endoplasmic reticulum targeting;GO:0005785//signal recognition particle receptor complex 716 tr|Q0VGD6|Q0VGD6_HUMAN HNRPR protein (Fragment) OS=Homo sapiens GN=HNRPR PE=2 SV=1 81299 RAPFLVVFKAPRADSHGPGCRPPLCPGLVAYVDLDERAIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPRGSRGGRGGPAQQQRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIAQQPLQQGGDYSGNYGYNNDNQEFYQDTYGQQWK 111 10.5 4 10 4 6 2 1.149 1.036 1.42 3 2 3 - - * 1.201666667 0.197343187 tr|Q0VGD6|Q0VGD6_HUMAN 100 6.00E-18 gi|148697994|gb|EDL29941.1| heterogeneous nuclear ribonucleoprotein R [Mus musculus] 100 8.00E-19 sp|O43390|HNRPR_HUMAN Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens GN=HNRNPR PE=1 SV=1 100 0 H9EPF9 H9EPF9_MACMU Heterogeneous nuclear ribonucleoprotein R isoform 2 OS=Macaca mulatta GN=HNRNPR PE=2 SV=1 - - - - - - - K13161|1|0.0|736|bta:512479|heterogeneous nuclear ribonucleoprotein R GO:0000398//mRNA splicing, via spliceosome GO:0003723//RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0071013//catalytic step 2 spliceosome 717 tr|A0A024R6W0|A0A024R6W0_HUMAN Aspartate aminotransferase OS=Homo sapiens GN=GOT2 PE=3 SV=1 56971 MALLHSGRVLPGIAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKGMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKEFSIYMTKDGRISVAGVTSSNVGYLAHAIHQVTK 107 10.2 3 5 5 3 3 0.767 0.439 0.805 2 2 2 - - - 0.670333333 0.201239492 tr|A0A024R6W0|A0A024R6W0_HUMAN 100 0 gi|179104|gb|AAA35568.1| aspartate aminotransferase precursor (2.6.1.1) [Homo sapiens] >gi|119603394|gb|EAW82988.1| glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2), isoform CRA_a [Homo sapiens] >gi|119603395|gb|EAW82989.1| glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2), isoform CRA_a [Homo sapiens] 99.77 0 sp|P00505|AATM_HUMAN Aspartate aminotransferase, mitochondrial OS=Homo sapiens GN=GOT2 PE=1 SV=3 100 0 H2QB89 H2QB89_PANTR Aspartate aminotransferase OS=Pan troglodytes GN=ENSG00000125166 PE=3 SV=1 SPBC725.01 480 2.00E-135 COG1448 Aspartate/tyrosine/aromatic aminotransferase E Amino acid transport and metabolism ; K14455|1|0.0|854|hsa:2806|aspartate aminotransferase, mitochondrial [EC:2.6.1.1] GO:0006107//oxaloacetate metabolic process;GO:0015908//fatty acid transport;GO:0006533//aspartate catabolic process;GO:0019551//glutamate catabolic process to 2-oxoglutarate;GO:0006532//aspartate biosynthetic process;GO:0045471//response to ethanol;GO:0034641//cellular nitrogen compound metabolic process;GO:0019550//glutamate catabolic process to aspartate;GO:0019470//4-hydroxyproline catabolic process;GO:0006094//gluconeogenesis GO:0004069//L-aspartate:2-oxoglutarate aminotransferase activity;GO:0005543//phospholipid binding;GO:0080130//L-phenylalanine:2-oxoglutarate aminotransferase activity;GO:0019899//enzyme binding;GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0016597//amino acid binding;GO:0042803//protein homodimerization activity;GO:0030170//pyridoxal phosphate binding GO:0043234//protein complex;GO:0005743//mitochondrial inner membrane;GO:0009986//cell surface;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane;GO:0043204//perikaryon 718 sp|Q01469|FABP5_HUMAN Fatty acid-binding protein, epidermal OS=Homo sapiens GN=FABP5 PE=1 SV=3 >tr|E7DVW5|E7DVW5_HUMAN Fatty acid binding protein 5 (Psoriasis-associated) OS=Homo sapiens GN=FABP5 PE=3 SV=1 20060 MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTLKTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVECVMNNVTCTRIYEKVE 60 11.9 - 4 4 2 2 0.979 2.254 0.801 2 2 2 - - - 1.344666667 0.79251898 sp|Q01469|FABP5_HUMAN 100 9.00E-63 gi|119607495|gb|EAW87089.1| hCG1984476, isoform CRA_b [Homo sapiens] 100 2.00E-74 sp|Q01469|FABP5_HUMAN Fatty acid-binding protein, epidermal OS=Homo sapiens GN=FABP5 PE=1 SV=3 100 1.00E-56 G3S0U2 G3S0U2_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=FABP5 PE=4 SV=1 - - - - - - - K08754|1|2e-74|276|ptr:746909|fatty acid-binding protein 5, epidermal GO:0008544//epidermis development;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006006//glucose metabolic process;GO:0015758//glucose transport GO:0005515//protein binding;GO:0005504//fatty acid binding;GO:0005215//transporter activity GO:0005737//cytoplasm 719 tr|B2RD27|B2RD27_HUMAN cDNA, FLJ96428, highly similar to Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) (PSMD7), mRNA OS=Homo sapiens PE=2 SV=1 49214 MPELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAAPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDLFNLLPDVSLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEKKEGQEKEESKKDRKEDKEKDKDKEKSDVKKEEKKEKK 66 3.4 3 2 2 1 1 1.153 0.492 0.596 2 2 2 - - - 0.747 0.355430725 tr|B2RD27|B2RD27_HUMAN 100 6.00E-149 gi|189067539|dbj|BAG37774.1| unnamed protein product [Homo sapiens] 99.3 8.00E-149 sp|P51665|PSD7_HUMAN 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens GN=PSMD7 PE=1 SV=2 100 2.00E-148 B2RD27 B2RD27_HUMAN cDNA, FLJ96428, highly similar to Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) (PSMD7), mRNA OS=Homo sapiens PE=2 SV=1 SPCC1682.10 319 4.00E-87 COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily R General function prediction only ; K03038|1|4e-149|527|mcc:705581|26S proteasome regulatory subunit N8 GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0016032//viral reproduction;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest - GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle 720 tr|A0A024RA27|A0A024RA27_HUMAN Heterogeneous nuclear ribonucleoprotein A2/B1, isoform CRA_b OS=Homo sapiens GN=HNRPA2B1 PE=4 SV=1 41212 MEREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSRY 163 17 1 15 15 6 6 1.533 1.258 1.316 6 6 6 * - - 1.369 0.144958615 tr|A0A024RA27|A0A024RA27_HUMAN 100 1.00E-105 gi|119614240|gb|EAW93834.1| heterogeneous nuclear ribonucleoprotein A2/B1, isoform CRA_a [Homo sapiens] 100 9.00E-108 sp|Q2HJ60|ROA2_BOVIN Heterogeneous nuclear ribonucleoproteins A2/B1 OS=Bos taurus GN=HNRNPA2B1 PE=2 SV=1 100 3.00E-106 F6QE81 F6QE81_MACMU Uncharacterized protein OS=Macaca mulatta GN=Mmu.2765 PE=4 SV=1 ECU03g0730 60.8 3.00E-09 COG0724 RNA-binding proteins (RRM domain) R General function prediction only ; K13158|1|9e-108|390|bta:507564|heterogeneous nuclear ribonucleoprotein A2/B1 GO:0050658//RNA transport;GO:0048025//negative regulation of mRNA splicing, via spliceosome GO:0097157//pre-mRNA intronic binding;GO:0043047//single-stranded telomeric DNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding GO:0005730//nucleolus;GO:0071013//catalytic step 2 spliceosome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm 721 sp|Q68BL8|OLM2B_HUMAN Olfactomedin-like protein 2B OS=Homo sapiens GN=OLFML2B PE=2 SV=2 94061 MAKPRLLVLYFALIVVPAWVSSIVLTGTSEPPDAQTVAPAEDETLQNEADNQENVLSQLLGDYDKVKAMSEGSDCQCKCVVRPLGRDACQRINAGASRKEDFYTVETITSGSSCKCACVAPPSALNPCEGDFRLQKLREADSQDLKLSTIIDMLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDMEEIRTEMNKRGKENCSENILDSMPDIRSALQRDAAAAYAHPEYEERFLQEETVSQQINSIELLQTRPLALPEVVKSQRPLQRQVHLRGRPASQPTVIRGITYYKAKVSEEENDIEEQQDEFFSGDNGVDLLIEDQLLRHNGLMTSVTRRPAATRQGHSTAVTSDLNARTAPWSSALPQPSTSDPSIANHASVGPTLQTTSVSPDPTRESVLQPSPQVPATTVAHTATQQPAAPAPPAVSPREALMEAMHTVPVPPTTVRTDSLGKDAPAGWGTTPASPTLSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDERIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPYSWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFSQEVIVLSKLNAADLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQVTYHVIFAY 135 4.1 - 5 5 2 2 1.201 5.787 3.456 2 3 2 - - * 3.481333333 2.293104955 sp|Q68BL8|OLM2B_HUMAN 100 0 gi|46195719|ref|NP_056256.1| olfactomedin-like protein 2B precursor [Homo sapiens] >gi|160418997|sp|Q68BL8.2|OLM2B_HUMAN RecName: Full=Olfactomedin-like protein 2B; AltName: Full=Photomedin-2; Flags: Precursor >gi|45501067|gb|AAH67274.1| Olfactomedin-like 2B [Homo sapiens] 100 0 sp|Q68BL8|OLM2B_HUMAN Olfactomedin-like protein 2B OS=Homo sapiens GN=OLFML2B PE=2 SV=2 100 2.00E-47 H0YEW8 H0YEW8_HUMAN Olfactomedin-like protein 2B (Fragment) OS=Homo sapiens GN=OLFML2B PE=4 SV=1 - - - - - - - K04592|1|5e-48|193|mmu:330814|latrophilin 1 GO:0030198//extracellular matrix organization GO:0050840//extracellular matrix binding GO:0005576//extracellular region;GO:0031012//extracellular matrix 722 tr|B4E324|B4E324_HUMAN cDNA FLJ60397, highly similar to Lysosomal protective protein (EC 3.4.16.5) OS=Homo sapiens PE=2 SV=1 61441 MTSSPRAPPGEQGRGGAEMIRAAPPPLFLLLLPLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLIANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTWESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMEPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY 676 13.8 4 27 27 5 5 1.818 1.274 2.143 19 20 19 * * * 1.745 0.439075164 tr|B4E324|B4E324_HUMAN 100 0 gi|194385922|dbj|BAG65336.1| unnamed protein product [Homo sapiens] 95.88 0 sp|P10619|PPGB_HUMAN Lysosomal protective protein OS=Homo sapiens GN=CTSA PE=1 SV=2 100 0 B4E324 B4E324_HUMAN cDNA FLJ60397, highly similar to Lysosomal protective protein (EC 3.4.16.5) OS=Homo sapiens PE=2 SV=1 YBR139w 169 1.00E-41 COG2939 Carboxypeptidase C (cathepsin A) E Amino acid transport and metabolism ; K13289|1|0.0|949|hsa:5476|cathepsin A (carboxypeptidase C) [EC:3.4.16.5] GO:0006644//phospholipid metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006508//proteolysis;GO:0006886//intracellular protein transport;GO:0044281//small molecule metabolic process;GO:0043085//positive regulation of catalytic activity GO:0008047//enzyme activator activity;GO:0004185//serine-type carboxypeptidase activity GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0043202//lysosomal lumen;GO:0005783//endoplasmic reticulum 723 tr|A0A087WUZ3|A0A087WUZ3_HUMAN Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens GN=SPTBN1 PE=1 SV=1 330214 MTTTVATDYDNIEIQQQYSDVNNRWDVDDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLVLSQDYGKHLLGVEDLLQKHTLVEADIGIQAERVRGVNASAQKFATDGEGYKPCDPQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRPTLDTLHEQASALPQEHAESPDVRGRLSGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSEKEIKAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNRETASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYGKDLTSVNILLKKQQATMLENQMEVRKKEIEELQSQAQALSQEGKSTDEVDSKRLTVQTKFMELLEPLNERKHNLLASKEIHQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGLLIEETEKRHRRLEEAHRAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLDERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHFTMLQERFREFARDTGNIGQERVDTVNHLADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQDKHKKLPEELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKSLLDACESRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPEPSTKVSEEAESQQQWDTSKGEQVSQNGLPAEQGSPRMAETVDTSEMVNGATEQRTSSKESSPIPSPTSDRKAKTALPAQSAATLPARTQETPSAQMEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKTAASGIPYHSEVPVSLKEAVCEVALDYKKKKHVFKLRLNDGNEYLFQAKDDEEMNTWIQAISSAISSDKHEVSASTQSTPASSRAQTLPTSVVTITSESSPGKREKDKEKDKEKRFSLFGKKK 258 5.7 2 18 16 11 10 0.731 0.803 0.652 11 11 11 - - * 0.728666667 0.075527037 tr|A0A087WUZ3|A0A087WUZ3_HUMAN 99.87 0 gi|62988842|gb|AAY24229.1| unknown [Homo sapiens] 99.87 0 sp|Q01082|SPTB2_HUMAN Spectrin beta chain, brain 1 OS=Homo sapiens GN=SPTBN1 PE=1 SV=2 99.87 0 B2ZZ89 B2ZZ89_HUMAN Spectrin beta non-erythrocytic 1 OS=Homo sapiens GN=SPTBN1 PE=2 SV=1 SPAC15A10.08 260 2.00E-68 COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) Z Cytoskeleton ; K06115|1|0.0|4559|hsa:6711|spectrin beta GO:0007411//axon guidance;GO:0071709//membrane assembly;GO:0072661//protein targeting to plasma membrane;GO:0007182//common-partner SMAD protein phosphorylation;GO:0000281//cytokinesis after mitosis;GO:0051693//actin filament capping;GO:0043001//Golgi to plasma membrane protein transport;GO:0007184//SMAD protein import into nucleus GO:0030506//ankyrin binding;GO:0005543//phospholipid binding;GO:0003779//actin binding;GO:0005516//calmodulin binding;GO:0005200//structural constituent of cytoskeleton GO:0014731//spectrin-associated cytoskeleton;GO:0008091//spectrin;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0031430//M band;GO:0032437//cuticular plate;GO:0005886//plasma membrane 724 tr|J3KQ18|J3KQ18_HUMAN D-dopachrome decarboxylase OS=Homo sapiens GN=DDT PE=1 SV=1 15819 MQLFLLAVSVPLPAMPFLELDTNLPANRVPAGLEKRLCAAAASILGKPADRVNVTVRPGLAMALSGSTEPCAQLSISSIGVVGTAEDNRSHSAHFFEFLTKELALGQDRILIRFFPLESWQIGKIGTVMTFL 154 19.7 1 8 8 2 2 0.753 0.71 0.731 7 7 7 * * * 0.731333333 0.021501938 tr|J3KQ18|J3KQ18_HUMAN 100 1.00E-48 gi|119580026|gb|EAW59622.1| D-dopachrome tautomerase, isoform CRA_a [Homo sapiens] 100 6.00E-64 sp|P30046|DOPD_HUMAN D-dopachrome decarboxylase OS=Homo sapiens GN=DDT PE=1 SV=3 100 3.00E-12 H2PCJ8 H2PCJ8_PONAB Uncharacterized protein OS=Pongo abelii GN=DDT PE=4 SV=1 - - - - - - - K10028|1|5e-64|242|hsa:1652|D-dopachrome decarboxylase [EC:4.1.1.84] GO:0042438//melanin biosynthetic process GO:0004167//dopachrome isomerase activity;GO:0033981//D-dopachrome decarboxylase activity GO:0005737//cytoplasm 725 tr|A0A024RA82|A0A024RA82_HUMAN HCG37272, isoform CRA_b OS=Homo sapiens GN=hCG_37272 PE=4 SV=1 73195 MCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHCPANLVLHKGRCIKPVLCPQR 42 2.5 1 2 2 1 1 0.921 0.807 0.791 2 2 2 - - - 0.839666667 0.070889586 tr|A0A024RA82|A0A024RA82_HUMAN 100 0 gi|38173826|gb|AAH60868.1| BMPER protein [Homo sapiens] 100 0 sp|Q8N8U9|BMPER_HUMAN BMP-binding endothelial regulator protein OS=Homo sapiens GN=BMPER PE=1 SV=3 100 2.00E-97 H9FK49 H9FK49_MACMU BMP-binding endothelial regulator protein (Fragment) OS=Macaca mulatta GN=BMPER PE=2 SV=1 - - - - - - - K03900|1|1e-39|164|dpo:Dpse_GA20020|von Willebrand factor GO:0060393//regulation of pathway-restricted SMAD protein phosphorylation;GO:0030514//negative regulation of BMP signaling pathway;GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0001657//ureteric bud development;GO:0042118//endothelial cell activation;GO:0048839//inner ear development;GO:0010594//regulation of endothelial cell migration - GO:0005615//extracellular space 726 sp|P11021|GRP78_HUMAN 78 kDa glucose-regulated protein OS=Homo sapiens GN=HSPA5 PE=1 SV=2 >tr|V9HWB4|V9HWB4_HUMAN Epididymis secretory sperm binding protein Li 89n OS=Homo sapiens GN=HEL-S-89n PE=2 SV=1 91263 MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDEL 1889 31.3 - 105 91 15 14 0.908 0.835 0.966 65 65 65 - * - 0.903 0.065642974 sp|P11021|GRP78_HUMAN 100 0 gi|350579657|ref|XP_001927830.3| PREDICTED: 78 kDa glucose-regulated protein [Sus scrofa] 100 0 sp|P11021|GRP78_HUMAN 78 kDa glucose-regulated protein OS=Homo sapiens GN=HSPA5 PE=1 SV=2 100 0 G3S6H1 G3S6H1_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=HSPA5 PE=3 SV=1 SPAC22A12.15c 879 0 COG0443 Molecular chaperone O Posttranslational modification, protein turnover, chaperones ; K09490|1|0.0|1249|mcc:703193|heat shock 70kDa protein 5 GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0021589//cerebellum structural organization;GO:0040019//positive regulation of embryonic development;GO:0006200//ATP catabolic process;GO:0030168//platelet activation;GO:0031398//positive regulation of protein ubiquitination;GO:0030433//ER-associated protein catabolic process;GO:0021680//cerebellar Purkinje cell layer development;GO:0006983//ER overload response;GO:0002576//platelet degranulation;GO:0042149//cellular response to glucose starvation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0060904//regulation of protein folding in endoplasmic reticulum;GO:0006987//activation of signaling protein activity involved in unfolded protein response GO:0051087//chaperone binding;GO:0051082//unfolded protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0019904//protein domain specific binding;GO:0043022//ribosome binding;GO:0005524//ATP binding;GO:0051787//misfolded protein binding;GO:0016887//ATPase activity;GO:0030674//protein binding, bridging;GO:0005509//calcium ion binding GO:0009986//cell surface;GO:0034663//endoplasmic reticulum chaperone complex;GO:0030496//midbody;GO:0005788//endoplasmic reticulum lumen;GO:0030176//integral to endoplasmic reticulum membrane;GO:0008180//signalosome;GO:0048471//perinuclear region of cytoplasm;GO:0042470//melanosome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment 727 tr|K7EL96|K7EL96_HUMAN Perilipin-3 (Fragment) OS=Homo sapiens GN=PLIN3 PE=1 SV=3 22133 MPLISSTCDMVSAAYASTKESYPHIKTVCDAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWADNHL 126 19.7 2 4 4 2 2 1.039 0.748 0.643 3 3 3 - - * 0.81 0.205151164 tr|K7EL96|K7EL96_HUMAN 100 6.00E-95 gi|255958289|ref|NP_001157661.1| perilipin-3 isoform 2 [Homo sapiens] 100 8.00E-96 sp|O60664|PLIN3_HUMAN Perilipin-3 OS=Homo sapiens GN=PLIN3 PE=1 SV=3 98.84 9.00E-94 H2QF25 H2QF25_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000105355 PE=4 SV=1 - - - - - - - K08768|1|1e-23|109|oaa:100076046|perilipin GO:0016192//vesicle-mediated transport GO:0005515//protein binding GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0005811//lipid particle 728 tr|J3KS31|J3KS31_HUMAN BUB3-interacting and GLEBS motif-containing protein ZNF207 (Fragment) OS=Homo sapiens GN=ZNF207 PE=1 SV=1 38174 XGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGRY 72 3.8 6 2 2 1 1 0.797 1.389 1.531 2 2 2 - - - 1.239 0.389312214 tr|J3KS31|J3KS31_HUMAN 100 1.00E-18 gi|67967964|dbj|BAE00464.1| unnamed protein product [Macaca fascicularis] 100 5.00E-25 sp|O43670|ZN207_HUMAN Zinc finger protein 207 OS=Homo sapiens GN=ZNF207 PE=1 SV=1 100 1.00E-23 G1R225 G1R225_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=ZNF207 PE=4 SV=1 - - - - - - - - - - 729 sp|P30040|ERP29_HUMAN Endoplasmic reticulum resident protein 29 OS=Homo sapiens GN=ERP29 PE=1 SV=4 >tr|V9HW71|V9HW71_HUMAN Endoplasmic reticulum resident protein 29 OS=Homo sapiens GN=HEL-S-107 PE=2 SV=1 37550 MAAAVPRAAFLSPLLPLLLGFLLLSAPHGGSGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFRDGDFENPVPYTGAVKVGAIQRWLKGQGVYLGMPGCLPVYDALAGEFIRASGVEARQALLKQGQDNLSSVKETQKKWAEQYLKIMGKILDQGEDFPASEMTRIARLIEKNKMSDGKKEELQKSLNILTAFQKKGAEKEEL 147 14.2 - 7 7 3 3 0.78 0.87 0.84 5 5 5 - - - 0.83 0.045825757 sp|P30040|ERP29_HUMAN 100 1.00E-135 gi|5803013|ref|NP_006808.1| endoplasmic reticulum resident protein 29 isoform 1 precursor [Homo sapiens] >gi|6015110|sp|P30040.4|ERP29_HUMAN RecName: Full=Endoplasmic reticulum resident protein 29; Short=ERp29; AltName: Full=Endoplasmic reticulum resident protein 28; Short=ERp28; AltName: Full=Endoplasmic reticulum resident protein 31; Short=ERp31; Flags: Precursor >gi|3413293|emb|CAA64397.1| ERp28 [Homo sapiens] >gi|49456295|emb|CAG46468.1| C12orf8 [Homo sapiens] >gi|75517097|gb|AAI01496.1| Endoplasmic reticulum protein 29 [Homo sapiens] >gi|75517652|gb|AAI01494.1| Endoplasmic reticulum protein 29, isoform 1 precursor [Homo sapiens] >gi|119618396|gb|EAW97990.1| endoplasmic reticulum protein 29, isoform CRA_a [Homo sapiens] >gi|119618397|gb|EAW97991.1| endoplasmic reticulum protein 29, isoform CRA_a [Homo sapiens] 100 2.00E-136 sp|P30040|ERP29_HUMAN Endoplasmic reticulum resident protein 29 OS=Homo sapiens GN=ERP29 PE=1 SV=4 100 2.00E-87 F8VY02 F8VY02_HUMAN Endoplasmic reticulum resident protein 29 OS=Homo sapiens GN=ERP29 PE=4 SV=1 SPAC17H9.14c 52 9.00E-07 COG0526 Thiol-disulfide isomerase and thioredoxins OC Posttranslational modification, protein turnover, chaperones ; Energy production and conversion ; K09586|1|7e-136|483|pon:100437310|endoplasmic reticulum protein 29 GO:0006457//protein folding;GO:0006886//intracellular protein transport;GO:0009306//protein secretion GO:0003756//protein disulfide isomerase activity GO:0005788//endoplasmic reticulum lumen;GO:0042470//melanosome 730 tr|Q6MZZ3|Q6MZZ3_HUMAN Putative uncharacterized protein DKFZp686I0746 OS=Homo sapiens GN=DKFZp686I0746 PE=2 SV=1 170495 MAQSKRHVYSRTPSGSRMSAEASARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKREGTDTTAKTSKLRGLKPKKAPTARKTTTRRPKPTRPASTGVAGASSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMGVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEKFELSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDCTMQLADHIKFTQSALDCMSVEVGRLRAFLQGGQEATDIALLLRDLETSCSDIRQFCKKIRRRMPGTDAPGIPAALAFGPQVSDTLLDCRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLLVAALEELAFKASEQIYGTPSSSPYECLRQSCNILISTMNKLATAMQEGEYDAERPPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKGFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGEEQQRGAIPGQAPGSVPGPGLVKDSPLLLQQISAMRLHISQLQHENSILKGAQMKASLASLPPLHVAKLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTHVVDITRTSPAAKSPSAQLMEQVAQLKSLSDTVEKLKDEVLKETVSQRPGATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGFGQRHRLVLTQEQLHQLHSRLIS 133 4.6 2 7 7 5 5 0.751 0.744 0.867 4 5 6 * * - 0.787333333 0.069082077 tr|Q6MZZ3|Q6MZZ3_HUMAN 100 5.00E-47 gi|78100782|pdb|1TXQ|A Chain A, Crystal Structure Of The Eb1 C-Terminal Domain Complexed With The Cap-Gly Domain Of P150glued >gi|159794790|pdb|2HQH|A Chain A, Crystal Structure Of P150glued And Clip-170 >gi|159794791|pdb|2HQH|B Chain B, Crystal Structure Of P150glued And Clip-170 >gi|159794792|pdb|2HQH|C Chain C, Crystal Structure Of P150glued And Clip-170 >gi|159794793|pdb|2HQH|D Chain D, Crystal Structure Of P150glued And Clip-170 99.84 0 sp|Q14203|DCTN1_HUMAN Dynactin subunit 1 OS=Homo sapiens GN=DCTN1 PE=1 SV=3 100 0 Q6MZZ3 Q6MZZ3_HUMAN Putative uncharacterized protein DKFZp686I0746 OS=Homo sapiens GN=DKFZp686I0746 PE=2 SV=1 SPAC27D7.13c 79 5.00E-14 COG5244 Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B D Cell cycle control, cell division, chromosome partitioning ; K04648|1|0.0|2238|hsa:1639|dynactin 1 GO:0006810//transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007067//mitosis;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0008219//cell death;GO:0007399//nervous system development;GO:0000086//G2/M transition of mitotic cell cycle GO:0005515//protein binding;GO:0003774//motor activity GO:0005829//cytosol;GO:0005874//microtubule;GO:0031252//cell leading edge;GO:0000776//kinetochore;GO:0005813//centrosome;GO:0005868//cytoplasmic dynein complex;GO:0000922//spindle pole 731 tr|Q5HYE3|Q5HYE3_HUMAN Putative uncharacterized protein DKFZp686H1812 OS=Homo sapiens GN=DKFZp686H1812 PE=2 SV=1 53649 MMVALRGASALLVLFLAAFLPPPQCTQDPAMVHYIYQRFRVLEQGLEKCTQATRAYIQEFQEFSKNISVMLGRCQTYTSEYKSAVGNLALRVERAQREIDYIQYLREADECIVSEDKTLAEMLLQEAEEEKKIRTLLNASCDNMLMGIKSLKIVKKMMDTHGSWMEDAVYNSPKVYLLIGSRNNTVWEFANIRAFMEDNTKPAPRKQILTLSWQGTGQVIYKGFLFFHNQATSNEIIKYNLQKRTVEDRMLLPGGVGRALVYQHSPSTYIDLAVDEHGLWAIHSGPGTHSHLVLTKIEPGTLGVEHSWDTPCRSQDAEASFLLCGVLYVVYSTGGQGPHRITCIYDPLGTISEEDLPNLFFPKRPRSHSMIHYNPRDKQLYAWNEGNQIIYKLQTKRKLPLK 104 10.9 1 4 4 3 3 2.363 4.516 3.322 2 2 2 - - - 3.400333333 1.078635403 tr|Q5HYE3|Q5HYE3_HUMAN 100 0 gi|57997553|emb|CAI46097.1| hypothetical protein [Homo sapiens] 99.5 0 sp|Q6UWY5|OLFL1_HUMAN Olfactomedin-like protein 1 OS=Homo sapiens GN=OLFML1 PE=1 SV=2 100 0 Q5HYE3 Q5HYE3_HUMAN Putative uncharacterized protein DKFZp686H1812 OS=Homo sapiens GN=DKFZp686H1812 PE=2 SV=1 - - - - - - - K04593|1|4e-25|116|mmu:99633|latrophilin 2 - - GO:0005576//extracellular region 732 tr|Q9HBP0|Q9HBP0_HUMAN Putative uncharacterized protein OS=Homo sapiens PE=2 SV=1 59174 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVIQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS 172 15.7 2 19 19 6 6 0.556 0.525 0.51 7 7 7 * * * 0.530333333 0.023459184 tr|Q9HBP0|Q9HBP0_HUMAN 100 2.00E-71 gi|157461313|gb|ABV57182.1| inhibin alpha-subunit [Aonyx capensis] >gi|157461315|gb|ABV57183.1| inhibin alpha-subunit [Aonyx cinerea] >gi|157461317|gb|ABV57184.1| inhibin alpha-subunit [Enhydra lutris] >gi|157461319|gb|ABV57185.1| inhibin alpha-subunit [Lontra canadensis] >gi|157461321|gb|ABV57186.1| inhibin alpha-subunit [Lontra felina] >gi|157461323|gb|ABV57187.1| inhibin alpha-subunit [Lontra longicaudis] >gi|157461325|gb|ABV57188.1| inhibin alpha-subunit [Lutra lutra] >gi|157461329|gb|ABV57190.1| inhibin alpha-subunit [Pteronura brasiliensis] >gi|157461331|gb|ABV57191.1| inhibin alpha-subunit [Lutra sumatrana] >gi|157461333|gb|ABV57192.1| inhibin alpha-subunit [Lutrogale perspicillata] >gi|157461341|gb|ABV57196.1| inhibin alpha-subunit [Mustela erminea] >gi|157461345|gb|ABV57198.1| inhibin alpha-subunit [Mustela frenata] >gi|157461347|gb|ABV57199.1| inhibin alpha-subunit [Mustela lutreola] >gi|157461349|gb|ABV57200.1| inhibin alpha-subunit [Mustela nigripes] >gi|157461353|gb|ABV57202.1| inhibin alpha-subunit [Mustela putorius] >gi|157461355|gb|ABV57203.1| inhibin alpha-subunit [Mustela sibirica] >gi|157461357|gb|ABV57204.1| inhibin alpha-subunit [Mustela strigidorsa] >gi|157461359|gb|ABV57205.1| inhibin alpha-subunit [Neovison vison] >gi|157461363|gb|ABV57207.1| inhibin alpha-subunit [Martes flavigula] >gi|157461371|gb|ABV57211.1| inhibin alpha-subunit [Martes pennanti] >gi|157461379|gb|ABV57215.1| inhibin alpha-subunit [Ictonyx striatus] >gi|157461381|gb|ABV57216.1| inhibin alpha-subunit [Galictis vittata] >gi|157461383|gb|ABV57217.1| inhibin alpha-subunit [Galictis cuja] >gi|157461385|gb|ABV57218.1| inhibin alpha-subunit [Arctonyx collaris] >gi|157461387|gb|ABV57219.1| inhibin alpha-subunit [Meles meles] >gi|157461389|gb|ABV57220.1| inhibin alpha-subunit [Mellivora capensis] >gi|157461393|gb|ABV57222.1| inhibin alpha-subunit [Taxidea taxus] >gi|157461395|gb|ABV57223.1| inhibin alpha-subunit [Bassariscus astutus] 99.77 0 sp|P08476|INHBA_HUMAN Inhibin beta A chain OS=Homo sapiens GN=INHBA PE=1 SV=2 100 1.00E-67 Q6V1X6 Q6V1X6_CERNI Activin beta A peptide (Fragment) OS=Cervus nippon PE=3 SV=1 - - - - - - - K04667|1|0.0|814|pon:100439592|inhibin, beta GO:0032925//regulation of activin receptor signaling pathway;GO:0060279//positive regulation of ovulation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0045578//negative regulation of B cell differentiation;GO:0001541//ovarian follicle development;GO:0045650//negative regulation of macrophage differentiation;GO:0006952//defense response;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0048333//mesodermal cell differentiation;GO:0051799//negative regulation of hair follicle development;GO:0045077//negative regulation of interferon-gamma biosynthetic process;GO:0042476//odontogenesis;GO:0061029//eyelid development in camera-type eye;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042541//hemoglobin biosynthetic process;GO:0007399//nervous system development;GO:0046882//negative regulation of follicle-stimulating hormone secretion;GO:0007050//cell cycle arrest;GO:0042326//negative regulation of phosphorylation;GO:0008285//negative regulation of cell proliferation;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0045648//positive regulation of erythrocyte differentiation;GO:0008584//male gonad development;GO:0060021//palate development;GO:0030308//negative regulation of cell growth;GO:0042701//progesterone secretion;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006917//induction of apoptosis;GO:0071397//cellular response to cholesterol GO:0008083//growth factor activity;GO:0017046//peptide hormone binding;GO:0005125//cytokine activity;GO:0070699//type II activin receptor binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0005179//hormone activity GO:0043512//inhibin A complex;GO:0043509//activin A complex 733 tr|B4DW52|B4DW52_HUMAN cDNA FLJ55253, highly similar to Actin, cytoplasmic 1 OS=Homo sapiens PE=2 SV=1 44122 MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 2123 36.6 8 139 43 11 4 0.683 0.469 0.54 25 25 25 * - * 0.564 0.109 tr|B4DW52|B4DW52_HUMAN 100 0 gi|194376310|dbj|BAG62914.1| unnamed protein product [Homo sapiens] 92.53 0 sp|P60713|ACTB_SHEEP Actin, cytoplasmic 1 OS=Ovis aries GN=ACTB PE=2 SV=1 100 0 B4DW52 B4DW52_HUMAN Actin, cytoplasmic 1, N-terminally processed OS=Homo sapiens GN=ACTB PE=2 SV=1 SPBC32H8.12c 654 0 COG5277 Actin and related proteins Z Cytoskeleton ; K05692|1|0.0|719|mcc:713687|actin beta/gamma 1 GO:0007411//axon guidance;GO:0034332//adherens junction organization;GO:0006928//cellular component movement;GO:0051592//response to calcium ion;GO:0045214//sarcomere organization;GO:0034329//cell junction assembly;GO:0007596//blood coagulation;GO:0051086//chaperone mediated protein folding independent of cofactor GO:0019901//protein kinase binding;GO:0050998//nitric-oxide synthase binding;GO:0019894//kinesin binding;GO:0030957//Tat protein binding;GO:0042802//identical protein binding;GO:0005524//ATP binding;GO:0005200//structural constituent of cytoskeleton GO:0030863//cortical cytoskeleton;GO:0031941//filamentous actin;GO:0005829//cytosol;GO:0030016//myofibril;GO:0030424//axon;GO:0014069//postsynaptic density;GO:0070688//MLL5-L complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0030529//ribonucleoprotein complex 734 sp|P07686|HEXB_HUMAN Beta-hexosaminidase subunit beta OS=Homo sapiens GN=HEXB PE=1 SV=3 >tr|A0A024RAJ6|A0A024RAJ6_HUMAN Beta-hexosaminidase OS=Homo sapiens GN=HEXB PE=3 SV=1 72654 MELCGLGLPRPPMLLALLLATLLAAMLALLTQVALVVQVAEAARAPSVSAKPGPALWPLPLSVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYHGYIFGFYKWHHEPAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFGPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTDFKKLESFYIQKVLDIIATINKGSIVWQEVFDDKAKLAPGTIVEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLDFGGTQKQKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWSSKDVRDMDDAYDRLTRHRCRMVERGIAAQPLYAGYCNHENM 611 15.5 - 36 36 8 8 1.24 0.988 1.125 27 28 27 * - - 1.117666667 0.126159951 sp|P07686|HEXB_HUMAN 100 0 gi|38492599|pdb|1O7A|A Chain A, Human Beta-Hexosaminidase B >gi|38492600|pdb|1O7A|B Chain B, Human Beta-Hexosaminidase B >gi|38492601|pdb|1O7A|C Chain C, Human Beta-Hexosaminidase B >gi|38492602|pdb|1O7A|D Chain D, Human Beta-Hexosaminidase B >gi|38492603|pdb|1O7A|E Chain E, Human Beta-Hexosaminidase B >gi|38492604|pdb|1O7A|F Chain F, Human Beta-Hexosaminidase B 100 0 sp|P07686|HEXB_HUMAN Beta-hexosaminidase subunit beta OS=Homo sapiens GN=HEXB PE=1 SV=3 100 0 Q5URX0 Q5URX0_HUMAN Beta-hexosaminidase subunit beta chain B OS=Homo sapiens GN=HEXB PE=2 SV=1 VC0613 177 6.00E-44 COG3525 N-acetyl-beta-hexosaminidase G Carbohydrate transport and metabolism ; K12373|1|0.0|1070|hsa:3074|hexosaminidase [EC:3.2.1.52] GO:0001501//skeletal system development;GO:0030207//chondroitin sulfate catabolic process;GO:0006689//ganglioside catabolic process;GO:0007605//sensory perception of sound;GO:0007626//locomotory behavior;GO:0008360//regulation of cell shape;GO:0006874//cellular calcium ion homeostasis;GO:0007040//lysosome organization;GO:0044267//cellular protein metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0008049//male courtship behavior;GO:0030214//hyaluronan catabolic process;GO:0019915//lipid storage;GO:0044281//small molecule metabolic process;GO:0008219//cell death;GO:0050885//neuromuscular process controlling balance;GO:0048477//oogenesis;GO:0042340//keratan sulfate catabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042552//myelination;GO:0009313//oligosaccharide catabolic process;GO:0008654//phospholipid biosynthetic process;GO:0043615//astrocyte cell migration;GO:0007341//penetration of zona pellucida GO:0030246//carbohydrate binding;GO:0016231//beta-N-acetylglucosaminidase activity;GO:0046982//protein heterodimerization activity;GO:0043169//cation binding;GO:0042803//protein homodimerization activity GO:0001669//acrosomal vesicle;GO:0016020//membrane;GO:0043202//lysosomal lumen 735 sp|O95336|6PGL_HUMAN 6-phosphogluconolactonase OS=Homo sapiens GN=PGLS PE=1 SV=2 30553 MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGARARFALGLSGGSLVSMLARELPAAVAPAGPASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLPIPESQVITINPELPVEEAAEDYAKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL 284 34.5 - 17 17 6 6 0.636 0.914 0.713 10 10 10 - - * 0.754333333 0.143535129 sp|O95336|6PGL_HUMAN 100 2.00E-113 gi|6912586|ref|NP_036220.1| 6-phosphogluconolactonase [Homo sapiens] >gi|7387511|sp|O95336.2|6PGL_HUMAN RecName: Full=6-phosphogluconolactonase; Short=6PGL >gi|6018458|emb|CAB57866.1| 6-phosphogluconolactonase [Homo sapiens] >gi|15559293|gb|AAH14006.1| 6-phosphogluconolactonase [Homo sapiens] >gi|119605020|gb|EAW84614.1| 6-phosphogluconolactonase, isoform CRA_b [Homo sapiens] 100 2.00E-114 sp|O95336|6PGL_HUMAN 6-phosphogluconolactonase OS=Homo sapiens GN=PGLS PE=1 SV=2 99.61 4.00E-112 H2QFR4 H2QFR4_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000130313 PE=4 SV=1 SPCC16C4.10 170 2.00E-42 COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase G Carbohydrate transport and metabolism ; K01057|1|2e-114|411|hsa:25796|6-phosphogluconolactonase [EC:3.1.1.31] GO:0009051//pentose-phosphate shunt, oxidative branch GO:0048029//monosaccharide binding;GO:0017057//6-phosphogluconolactonase activity GO:0005829//cytosol 736 sp|P33908|MA1A1_HUMAN Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens GN=MAN1A1 PE=1 SV=3 86231 MPVGGLLPLFSSPAGGVLGGGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCFGAIFFLPDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAAEGRARRREEGAPGDPEAALEDNLARIRENHERALREAKETLQKLPEEIQRDILLEKKKVAQDQLRDKAPFRGLPPVDFVPPIGVESREPADAAIREKRAKIKEMMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGATIVDALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEIFRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLSGNPIFAEKVMNIRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLLKAWLMSDKTDLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGGMFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFDGGVEAIATRQNEKYYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDDVQQSFFLAETLKYLYLIFSDDDLLPLEHWIFNSEAHLLPILPKDKKEVEIREE 102 8.6 - 6 6 4 4 1.112 1.281 1.668 4 3 3 - - - 1.353666667 0.285033916 sp|P33908|MA1A1_HUMAN 100 0 gi|24497519|ref|NP_005898.2| mannosyl-oligosaccharide 1,2-alpha-mannosidase IA [Homo sapiens] >gi|62906886|sp|P33908.3|MA1A1_HUMAN RecName: Full=Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA; AltName: Full=Man(9)-alpha-mannosidase; Short=Man9-mannosidase; AltName: Full=Mannosidase alpha class 1A member 1; AltName: Full=Processing alpha-1,2-mannosidase IA; Short=Alpha-1,2-mannosidase IA >gi|119568572|gb|EAW48187.1| mannosidase, alpha, class 1A, member 1, isoform CRA_c [Homo sapiens] 100 0 sp|P33908|MA1A1_HUMAN Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens GN=MAN1A1 PE=1 SV=3 99.82 0 G3SJX6 G3SJX6_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=MAN1A1 PE=4 SV=1 - - - - - - - K01230|1|0.0|1237|ptr:463148|mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113] GO:0018279//protein N-linked glycosylation via asparagine;GO:0043687//post-translational protein modification GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding GO:0000139//Golgi membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0016021//integral to membrane;GO:0005783//endoplasmic reticulum 737 tr|H0YI98|H0YI98_HUMAN Dynactin subunit 2 (Fragment) OS=Homo sapiens GN=DCTN2 PE=1 SV=1 37028 VEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK 107 10.4 7 5 5 2 2 1.291 0.562 0.673 3 3 3 - * - 0.842 0.392786201 tr|H0YI98|H0YI98_HUMAN 94.04 9.00E-121 gi|387527972|ref|NP_001248341.1| dynactin subunit 2 isoform 2 [Homo sapiens] 94.04 1.00E-121 sp|Q13561|DCTN2_HUMAN Dynactin subunit 2 OS=Homo sapiens GN=DCTN2 PE=1 SV=4 100 2.00E-56 F8VW18 F8VW18_HUMAN Dynactin subunit 2 (Fragment) OS=Homo sapiens GN=DCTN2 PE=4 SV=1 - - - - - - - K10424|1|1e-122|439|ssc:100515661|dynactin 2 GO:0000086//G2/M transition of mitotic cell cycle;GO:0007052//mitotic spindle organization;GO:0007067//mitosis;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0008283//cell proliferation GO:0003774//motor activity;GO:0005515//protein binding GO:0005829//cytosol;GO:0030286//dynein complex;GO:0005874//microtubule;GO:0005813//centrosome;GO:0031982//vesicle;GO:0000776//kinetochore;GO:0030426//growth cone;GO:0005869//dynactin complex;GO:0016020//membrane;GO:0005634//nucleus 738 tr|D3DNU8|D3DNU8_HUMAN Kininogen 1, isoform CRA_a OS=Homo sapiens GN=KNG1 PE=4 SV=1 59249 MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRITEATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFSVATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFTLNEVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLRIASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFKIDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPWEKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTSHLRSCEYKGRPPKAGAEPASEREVS 84 2.1 4 3 3 1 1 0.907 1.086 0.888 3 3 3 - - - 0.960333333 0.109244374 tr|D3DNU8|D3DNU8_HUMAN 100 0 gi|62898910|dbj|BAD97309.1| kininogen 1 variant [Homo sapiens] >gi|119598585|gb|EAW78179.1| kininogen 1, isoform CRA_a [Homo sapiens] >gi|119598587|gb|EAW78181.1| kininogen 1, isoform CRA_a [Homo sapiens] 95 0 sp|P01042|KNG1_HUMAN Kininogen-1 OS=Homo sapiens GN=KNG1 PE=1 SV=2 100 0 D3DNU8 D3DNU8_HUMAN Kininogen 1, isoform CRA_a OS=Homo sapiens GN=KNG1 PE=4 SV=1 - - - - - - - K03898|1|0.0|816|hsa:3827|kininogen GO:0030168//platelet activation;GO:0035810//positive regulation of urine volume;GO:0007204//elevation of cytosolic calcium ion concentration;GO:0030195//negative regulation of blood coagulation;GO:0007162//negative regulation of cell adhesion;GO:0042311//vasodilation;GO:0007597//blood coagulation, intrinsic pathway;GO:0043065//positive regulation of apoptotic process;GO:0006954//inflammatory response;GO:0002576//platelet degranulation;GO:0006939//smooth muscle contraction;GO:0035815//positive regulation of renal sodium excretion;GO:0010466//negative regulation of peptidase activity GO:0005102//receptor binding;GO:0008270//zinc ion binding;GO:0008201//heparin binding;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005886//plasma membrane 739 sp|Q13185|CBX3_HUMAN Chromobox protein homolog 3 OS=Homo sapiens GN=CBX3 PE=1 SV=4 >tr|A4D177|A4D177_HUMAN Chromobox homolog 3 (HP1 gamma homolog, Drosophila) OS=Homo sapiens GN=CBX3 PE=4 SV=1 28879 MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPEDEAQ 92 12 - 4 4 2 2 1.741 0.867 1.209 2 2 2 - - - 1.272333333 0.440428579 sp|Q13185|CBX3_HUMAN 100 4.00E-68 gi|15082258|ref|NP_009207.2| chromobox protein homolog 3 [Homo sapiens] >gi|20544151|ref|NP_057671.2| chromobox protein homolog 3 [Homo sapiens] >gi|56799436|ref|NP_001008314.2| chromobox homolog 3 [Rattus norvegicus] >gi|108860695|ref|NP_031650.3| chromobox protein homolog 3 [Mus musculus] >gi|155372117|ref|NP_001094668.1| chromobox protein homolog 3 [Bos taurus] >gi|197100961|ref|NP_001126464.1| chromobox protein homolog 3 [Pongo abelii] >gi|302191695|ref|NP_001180536.1| chromobox homolog 3 [Macaca mulatta] >gi|350539727|ref|NP_001233631.1| heterochromatin protein 1 gamma [Cricetulus griseus] >gi|73619718|sp|Q5R6X7.1|CBX3_PONAB RecName: Full=Chromobox protein homolog 3; AltName: Full=Heterochromatin protein 1 homolog gamma; Short=HP1 gamma >gi|116241284|sp|Q13185.4|CBX3_HUMAN RecName: Full=Chromobox protein homolog 3; AltName: Full=HECH; AltName: Full=Heterochromatin protein 1 homolog gamma; Short=HP1 gamma; AltName: Full=Modifier 2 protein >gi|12654267|gb|AAH00954.1| Chromobox homolog 3 (HP1 gamma homolog, Drosophila) [Homo sapiens] >gi|17390828|gb|AAH18354.1| Cbx3 protein [Mus musculus] >gi|37590524|gb|AAH59831.1| Cbx3 protein [Mus musculus] >gi|48249221|gb|AAT40863.1| heterochromatin protein 1 gamma [Cricetulus griseus] >gi|51094991|gb|EAL24235.1| chromobox homolog 3 (HP1 gamma homolog, Drosophila) [Homo sapiens] >gi|55778344|gb|AAH86601.1| Chromobox homolog 3 (HP1 gamma homolog, Drosophila) [Rattus norvegicus] >gi|117558386|gb|AAI27509.1| Chromobox homolog 3 (HP1 gamma homolog, Drosophila) [Rattus norvegicus] >gi|119612828|gb|EAW92422.1| coiled-coil domain containing 32, isoform CRA_c [Homo sapiens] >gi|119614248|gb|EAW93842.1| chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a [Homo sapiens] >gi|119614249|gb|EAW93843.1| chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a [Homo sapiens] >gi|119614250|gb|EAW93844.1| chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a [Homo sapiens] >gi|148666224|gb|EDK98640.1| mCG119115, isoform CRA_a [Mus musculus] >gi|148666226|gb|EDK98642.1| mCG119115, isoform CRA_a [Mus musculus] >gi|148877457|gb|AAI46195.1| CBX3 protein [Bos taurus] >gi|149033377|gb|EDL88178.1| chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a [Rattus norvegicus] >gi|149033378|gb|EDL88179.1| chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a [Rattus norvegicus] >gi|149033379|gb|EDL88180.1| chromobox homolog 3 (HP1 gamma homolog, Drosophila), isoform CRA_a [Rattus norvegicus] >gi|151554829|gb|AAI47956.1| CBX3 protein [Bos taurus] 100 6.00E-69 sp|Q5R6X7|CBX3_PONAB Chromobox protein homolog 3 OS=Pongo abelii GN=CBX3 PE=2 SV=1 100 1.00E-67 H9FPI2 H9FPI2_MACMU Chromobox protein homolog 3 OS=Macaca mulatta GN=CBX3 PE=2 SV=1 - - - - - - - K11586|1|4e-69|260|mdo:100010415|chromobox protein 3 GO:0045892//negative regulation of transcription, DNA-dependent;GO:0006338//chromatin remodeling GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding GO:0005719//nuclear euchromatin;GO:0005819//spindle;GO:0010369//chromocenter;GO:0000779//condensed chromosome, centromeric region;GO:0005637//nuclear inner membrane;GO:0031618//nuclear centromeric heterochromatin 740 tr|B4DVE1|B4DVE1_HUMAN cDNA FLJ53478, highly similar to Galectin-3-binding protein OS=Homo sapiens PE=2 SV=1 70995 MTPPRLFWVWLLVAGTQGVNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSRELSEALGQIFDSQRGCDLSISVNVQGEDALGFCGHTVILTANLEAQALWKEPGSNVTMSVDAECVPMVRDLLRYFYSRRIDITLSSVKCFHKLASAYGARQLQGYCASLFAILLPQDPSFQMPLDLYAYAVATGDALLEKLCLQFLAWNFEALTQAEAWPSVPTDLLQLLLPRSDLAVPSELALLKAVDTWSWGERASHEEVEGLVEKIRFPMMLPEELFELQFNLSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTSPTWSAFVTDSSWSARKSQLVYQSRRGPLVKYSSDYFQAPSDYRYYPYQSFQTPQHPSFLFQDKRVSWSLVYLPTIQSCWNYGFSCSSDELPVLGLTKSGGSDRTIAYENKALMLCEGLFVADVTDFEGWKAAIPSALDTNSSKSTSSFPCPAGHFNGFRTVIRPFYLTNSSGVD 1219 26.2 1 66 66 12 12 1.21 1.023 1.01 43 44 38 * - - 1.081 0.111906211 tr|B4DVE1|B4DVE1_HUMAN 100 0 gi|193786317|dbj|BAG51600.1| unnamed protein product [Homo sapiens] 97.95 0 sp|Q08380|LG3BP_HUMAN Galectin-3-binding protein OS=Homo sapiens GN=LGALS3BP PE=1 SV=1 100 0 B4DVE1 B4DVE1_HUMAN Galectin-3-binding protein OS=Homo sapiens GN=LGALS3BP PE=2 SV=1 - - - - - - - K13912|1|2e-24|114|mmu:12945|deleted in malignant brain tumors 1 protein GO:0006968//cellular defense response;GO:0007165//signal transduction;GO:0007155//cell adhesion GO:0005044//scavenger receptor activity GO:0016020//membrane;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 741 tr|D3DV26|D3DV26_HUMAN S100 calcium binding protein A10 (Annexin II ligand, calpactin I, light polypeptide (P11)), isoform CRA_b (Fragment) OS=Homo sapiens GN=S100A10 PE=4 SV=1 27935 REVYKNALSGAGEASARRVRERGQGVGRAPGVGGVGGRKRGRRQGWGSALPSARQAPPAPAPPPSTHPPHVLRKAHSPPRSPLRPASSSPSSPSVRRASAKASTDHTKMPSQMEHAMETMMFTFHKFAGDKGYLTKEDLRVLMEKEFPGFLENQKDPLAVDKIMKDLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK 225 8.3 2 13 13 2 2 1.153 0.931 1.232 8 8 8 - - * 1.105333333 0.15605875 tr|D3DV26|D3DV26_HUMAN 100 1.00E-54 gi|397492728|ref|XP_003817272.1| PREDICTED: protein S100-A10 isoform 2 [Pan paniscus] >gi|426331503|ref|XP_004026720.1| PREDICTED: protein S100-A10 isoform 3 [Gorilla gorilla gorilla] >gi|441676502|ref|XP_004092679.1| PREDICTED: protein S100-A10-like isoform 3 [Nomascus leucogenys] 100 6.00E-52 sp|P60902|S10AA_BOVIN Protein S100-A10 OS=Bos taurus GN=S100A10 PE=1 SV=2 100 1.00E-50 F2Z5M2 F2Z5M2_PIG Protein S100-A10 OS=Sus scrofa GN=S100A10 PE=4 SV=1 - - - - - - - K10384|1|9e-08|57.0|cfa:483211|filaggrin GO:0051099//positive regulation of binding;GO:0071229//cellular response to acid;GO:0007165//signal transduction GO:0005509//calcium ion binding;GO:0005102//receptor binding GO:0019897//extrinsic to plasma membrane 742 tr|A0A024RAR8|A0A024RAR8_HUMAN Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator, isoform CRA_a OS=Homo sapiens GN=ARTS-1 PE=4 SV=1 125959 MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPLQVLEHPPQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQRGFPLITITVRGRNVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEGSVSERMLRSELLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM 150 3.2 2 8 8 3 3 0.699 1.098 1.274 4 3 4 - - * 1.023666667 0.294618963 tr|A0A024RAR8|A0A024RAR8_HUMAN 100 0 gi|119616483|gb|EAW96077.1| type 1 tumor necrosis factor receptor shedding aminopeptidase regulator, isoform CRA_a [Homo sapiens] >gi|119616485|gb|EAW96079.1| type 1 tumor necrosis factor receptor shedding aminopeptidase regulator, isoform CRA_a [Homo sapiens] 99.68 0 sp|Q9NZ08|ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1 OS=Homo sapiens GN=ERAP1 PE=1 SV=3 99.79 0 A8K6H1 A8K6H1_HUMAN cDNA FLJ76662, highly similar to Homo sapiens type 1 tumor necrosis factor receptor shedding aminopeptidase regulator, mRNA OS=Homo sapiens PE=2 SV=1 SPBC1921.05 410 6.00E-114 COG0308 Aminopeptidase N E Amino acid transport and metabolism ; K09604|1|0.0|1848|hsa:51752|adipocyte-derived leucine aminopeptidase [EC:3.4.11.-] GO:0006509//membrane protein ectodomain proteolysis;GO:0045766//positive regulation of angiogenesis;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0008217//regulation of blood pressure;GO:0009617//response to bacterium;GO:0045088//regulation of innate immune response;GO:0045444//fat cell differentiation GO:0008270//zinc ion binding;GO:0004177//aminopeptidase activity;GO:0005138//interleukin-6 receptor binding;GO:0005164//tumor necrosis factor receptor binding;GO:0008235//metalloexopeptidase activity;GO:0005151//interleukin-1, Type II receptor binding GO:0005829//cytosol;GO:0016021//integral to membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005789//endoplasmic reticulum membrane 743 sp|P12111|CO6A3_HUMAN Collagen alpha-3(VI) chain OS=Homo sapiens GN=COL6A3 PE=1 SV=5 >tr|D9ZGF2|D9ZGF2_HUMAN Collagen, type VI, alpha 3 OS=Homo sapiens GN=COL6A3 PE=4 SV=1 393536 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATPAPPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGPKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEITENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVCYLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT 12622 31 - 548 548 80 80 2.156 2.378 2.403 370 374 372 - - - 2.312333333 0.135964456 sp|P12111|CO6A3_HUMAN 100 3.00E-101 gi|62822357|gb|AAY14906.1| unknown [Homo sapiens] 100 0 sp|P12111|CO6A3_HUMAN Collagen alpha-3(VI) chain OS=Homo sapiens GN=COL6A3 PE=1 SV=5 100 0 E9PFQ6 E9PFQ6_HUMAN Collagen alpha-3(VI) chain OS=Homo sapiens GN=COL6A3 PE=4 SV=1 - - - - - - - K06238|1|0.0|4055|hsa:1293|collagen, type VI, alpha GO:0007411//axon guidance;GO:0009749//response to glucose stimulus;GO:0007517//muscle organ development;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization GO:0004867//serine-type endopeptidase inhibitor activity GO:0030133//transport vesicle;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0042383//sarcolemma;GO:0005589//collagen type VI 744 tr|B1AKG0|B1AKG0_HUMAN Complement factor H-related protein 1 OS=Homo sapiens GN=CFHR1 PE=4 SV=1 36313 MWLLVSVILISRISSVGGEATFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCTEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRLQNNENNISCVERGWSTPPKCRSTDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTCAKR 49 7.7 1 3 3 2 2 0.671 3.069 0.787 2 2 2 - * - 1.509 1.352244061 tr|B1AKG0|B1AKG0_HUMAN 100 3.00E-68 gi|460417409|pdb|3ZD2|A Chain A, The Structure Of The Two N-terminal Domains Of Complement Factor H Related Protein 1 Shows Formation Of A Novel Dimerisation Interface >gi|460417410|pdb|3ZD2|B Chain B, The Structure Of The Two N-terminal Domains Of Complement Factor H Related Protein 1 Shows Formation Of A Novel Dimerisation Interface 86.35 8.00E-129 sp|P36980|FHR2_HUMAN Complement factor H-related protein 2 OS=Homo sapiens GN=CFHR2 PE=1 SV=1 100 1.00E-149 B1AKG0 B1AKG0_HUMAN Complement factor H-related 1 OS=Homo sapiens GN=CFHR1 PE=4 SV=1 - - - - - - - K04004|1|2e-76|285|hsa:3075|complement factor H GO:0006956//complement activation - GO:0005615//extracellular space 745 sp|P45974|UBP5_HUMAN Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens GN=USP5 PE=1 SV=2 112456 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCASEKPPKDLGYIYFYQRVAS 45 3.1 - 3 3 2 2 0.645 2.129 0.534 2 2 2 - - - 1.102666667 0.890561808 sp|P45974|UBP5_HUMAN 100 8.00E-73 gi|93279863|pdb|2G43|A Chain A, Structure Of The Znf Ubp Domain From Deubiquitinating Enzyme Isopeptidase T (Isot) >gi|93279864|pdb|2G43|B Chain B, Structure Of The Znf Ubp Domain From Deubiquitinating Enzyme Isopeptidase T (Isot) >gi|93279865|pdb|2G45|A Chain A, Co-Crystal Structure Of Znf Ubp Domain From The Deubiquitinating Enzyme Isopeptidase T (Isot) In Complex With Ubiquitin >gi|93279867|pdb|2G45|D Chain D, Co-Crystal Structure Of Znf Ubp Domain From The Deubiquitinating Enzyme Isopeptidase T (Isot) In Complex With Ubiquitin 100 0 sp|P45974|UBP5_HUMAN Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens GN=USP5 PE=1 SV=2 100 0 H2NGA3 H2NGA3_PONAB Ubiquitin carboxyl-terminal hydrolase OS=Pongo abelii GN=USP5 PE=3 SV=1 SPBC6B1.06c 405 2.00E-112 COG5207 Isopeptidase T O Posttranslational modification, protein turnover, chaperones ; K11836|1|0.0|1673|hsa:8078|ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.1.2.15] GO:0071108//protein K48-linked deubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0004221//ubiquitin thiolesterase activity;GO:0008242//omega peptidase activity;GO:0008270//zinc ion binding;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding GO:0005764//lysosome 746 tr|H0YHA7|H0YHA7_HUMAN 60S ribosomal protein L18 (Fragment) OS=Homo sapiens GN=RPL18 PE=1 SV=1 24001 XVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTITDDVRVQEVPKLKPCPLHQVCALRVTSRARSRILRAGGKILTFDQLALDSPKGCGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN 100 7.8 5 2 2 1 1 0.543 0.88 0.65 2 2 2 * - - 0.691 0.172200465 tr|H0YHA7|H0YHA7_HUMAN 96.39 6.00E-79 gi|397486092|ref|XP_003814166.1| PREDICTED: LOW QUALITY PROTEIN: D site-binding protein [Pan paniscus] 96.39 6.00E-79 sp|Q07020|RL18_HUMAN 60S ribosomal protein L18 OS=Homo sapiens GN=RPL18 PE=1 SV=2 100 2.00E-90 H0YHA7 H0YHA7_HUMAN 60S ribosomal protein L18 (Fragment) OS=Homo sapiens GN=RPL18 PE=3 SV=1 SPBC11C11.07 171 4.00E-43 COG1727 Ribosomal protein L18E J Translation, ribosomal structure and biogenesis ; K02883|1|7e-79|292|mcc:718136|large subunit ribosomal protein L18e GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006355//regulation of transcription, DNA-dependent;GO:0006414//translational elongation;GO:0006415//translational termination;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity GO:0022625//cytosolic large ribosomal subunit 747 sp|P05387|RLA2_HUMAN 60S acidic ribosomal protein P2 OS=Homo sapiens GN=RPLP2 PE=1 SV=1 >tr|A0A024RCA7|A0A024RCA7_HUMAN Ribosomal protein, large, P2, isoform CRA_a OS=Homo sapiens GN=RPLP2 PE=3 SV=1 15004 MRYVASYLLAALGGNSSPSAKDIKKILDSVGIEADDDRLNKVISELNGKNIEDVIAQGIGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD 358 69.6 - 12 12 4 4 1.449 1.147 1.375 10 10 10 * - - 1.323666667 0.157408174 sp|P05387|RLA2_HUMAN 100 2.00E-26 gi|268612104|pdb|2W1O|A Chain A, Nmr Structure Of Dimerization Domain Of Human Ribosomal Protein P2 >gi|268612105|pdb|2W1O|B Chain B, Nmr Structure Of Dimerization Domain Of Human Ribosomal Protein P2 >gi|361129719|pdb|2LBF|B Chain B, Solution Structure Of The Dimerization Domain Of Human Ribosomal Protein P1P2 HETERODIMER 100 3.00E-17 sp|P19943|RLA2_RABIT 60S acidic ribosomal protein P2 (Fragment) OS=Oryctolagus cuniculus GN=RPLP2 PE=1 SV=1 100 9.00E-27 G3R5E5 G3R5E5_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=RPLP2 PE=4 SV=1 SPBC23G7.15c 89 2.00E-18 COG2058 Ribosomal protein L12E/L44/L45/RPP1/RPP2 J Translation, ribosomal structure and biogenesis ; K02943|1|1e-28|124|ssc:100513643|large subunit ribosomal protein LP2 GO:0006412//translation;GO:0016071//mRNA metabolic process;GO:0019058//viral infectious cycle - GO:0022625//cytosolic large ribosomal subunit 748 tr|D3DR24|D3DR24_HUMAN Exostoses (Multiple) 2, isoform CRA_a OS=Homo sapiens GN=EXT2 PE=4 SV=1 96991 MLLECEEEAVCVIMCASVKYNIRGPALIPRMKTKHRIYYITLFSIVLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACLFVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEALQVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWGSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL 383 7.4 2 16 16 5 5 0.923 0.911 0.555 9 10 8 - - * 0.796333333 0.209086904 tr|D3DR24|D3DR24_HUMAN 100 5.00E-129 gi|402893734|ref|XP_003910044.1| PREDICTED: exostosin-2-like [Papio anubis] 100 0 sp|Q93063|EXT2_HUMAN Exostosin-2 OS=Homo sapiens GN=EXT2 PE=1 SV=1 100 0 D3DR24 D3DR24_HUMAN Exostoses (Multiple) 2, isoform CRA_a OS=Homo sapiens GN=EXT2 PE=4 SV=1 - - - - - - - K02367|1|0.0|1514|pon:100436160|glucuronyl/N-acetylglucosaminyl transferase EXT2 [EC:2.4.1.224 2.4.1.225] GO:0006024//glycosaminoglycan biosynthetic process;GO:0001503//ossification;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0030154//cell differentiation;GO:0006486//protein glycosylation;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0001707//mesoderm formation GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0050508//glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0042328//heparan sulfate N-acetylglucosaminyltransferase activity;GO:0050509//N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity GO:0016021//integral to membrane;GO:0000139//Golgi membrane;GO:0031227//intrinsic to endoplasmic reticulum membrane 749 tr|B2R7F8|B2R7F8_HUMAN cDNA, FLJ93426, highly similar to Homo sapiens plasminogen (PLG), mRNA OS=Homo sapiens PE=2 SV=1 108427 MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFTCRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTANPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN 110 5.3 2 3 3 3 3 0.944 --- --- 2 1 - - - - 0.944 - tr|B2R7F8|B2R7F8_HUMAN 100 9.00E-143 gi|433286580|pdb|3UIR|A Chain A, Crystal Structure Of The Plasmin-Textilinin-1 Complex >gi|433286581|pdb|3UIR|B Chain B, Crystal Structure Of The Plasmin-Textilinin-1 Complex 99.88 0 sp|P00747|PLMN_HUMAN Plasminogen OS=Homo sapiens GN=PLG PE=1 SV=2 100 4.00E-119 Q68DS2 Q68DS2_HUMAN Putative uncharacterized protein DKFZp779M0222 (Fragment) OS=Homo sapiens GN=DKFZp779M0222 PE=2 SV=1 mlr3307 110 9.00E-24 COG5640 Secreted trypsin-like serine protease O Posttranslational modification, protein turnover, chaperones ; K01315|1|0.0|1565|hsa:5340|plasminogen [EC:3.4.21.7] GO:0030168//platelet activation;GO:0022617//extracellular matrix disassembly;GO:0010812//negative regulation of cell-substrate adhesion;GO:0048771//tissue remodeling;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:0051918//negative regulation of fibrinolysis;GO:0051919//positive regulation of fibrinolysis;GO:0008285//negative regulation of cell proliferation;GO:0006508//proteolysis;GO:0002576//platelet degranulation GO:0034185//apolipoprotein binding;GO:0019904//protein domain specific binding;GO:0004252//serine-type endopeptidase activity;GO:0043498//cell surface binding GO:0031232//extrinsic to external side of plasma membrane;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen 750 tr|H0Y8C6|H0Y8C6_HUMAN Importin-5 (Fragment) OS=Homo sapiens GN=IPO5 PE=1 SV=1 143267 XFRPLLPRRLAPVTSPPPLAPTCGRSRRAPVQETYENIPGQSKITFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNLIDEDGNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAAMLRKHTNIVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVPLLKFYFHDGVRVAAAESMPLLLECARVRGPEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQWGLCIFDDVIEHCSPASFKYAEYFLRPMLQYVCDNSPEVRQAAAYGLGVMAQYGGDNYRPFCTEALPLLVRVIQSADSKTKENVNATENCISAVGKIMKFKPDCVNVEEVLPHWLSWLPLHEDKEEAVQTFNYLCDLIESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQELLNSA 324 10.6 1 15 15 9 9 0.732 0.557 0.752 9 10 10 * * * 0.680333333 0.1072769 tr|H0Y8C6|H0Y8C6_HUMAN 100 0 gi|332841543|ref|XP_001140931.2| PREDICTED: importin-5 [Pan troglodytes] >gi|194380888|dbj|BAG64012.1| unnamed protein product [Homo sapiens] 99.63 0 sp|O00410|IPO5_HUMAN Importin-5 OS=Homo sapiens GN=IPO5 PE=1 SV=4 100 0 Q9BVS9 Q9BVS9_HUMAN IPO5 protein (Fragment) OS=Homo sapiens GN=IPO5 PE=2 SV=1 SPAC1B1.03c 60.1 2.00E-08 COG5215 Karyopherin (importin) beta U Intracellular trafficking, secretion, and vesicular transport ; K14293|1|2e-06|55.8|bmy:Bm1_57540|importin subunit beta-1 GO:0006607//NLS-bearing substrate import into nucleus;GO:0019048//virus-host interaction;GO:0006610//ribosomal protein import into nucleus GO:0008565//protein transporter activity;GO:0008536//Ran GTPase binding;GO:0005095//GTPase inhibitor activity GO:0005730//nucleolus;GO:0005643//nuclear pore;GO:0005737//cytoplasm 751 tr|E9PEW8|E9PEW8_HUMAN Hemoglobin subunit delta (Fragment) OS=Homo sapiens GN=HBD PE=1 SV=1 14134 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENF 387 17.3 - 24 2 2 1 0.605 0.804 1.05 2 2 2 - * - 0.819666667 0.222913287 tr|E9PEW8|E9PEW8_HUMAN 100 2.00E-55 gi|48428925|sp|P61772.2|HBD_PANTR RecName: Full=Hemoglobin subunit delta; AltName: Full=Delta-globin; AltName: Full=Hemoglobin delta chain >gi|48428926|sp|P61773.2|HBD_GORGO RecName: Full=Hemoglobin subunit delta; AltName: Full=Delta-globin; AltName: Full=Hemoglobin delta chain >gi|48428927|sp|P61774.2|HBD_HYLLA RecName: Full=Hemoglobin subunit delta; AltName: Full=Delta-globin; AltName: Full=Hemoglobin delta chain >gi|48428928|sp|P61775.2|HBD_PONPY RecName: Full=Hemoglobin subunit delta; AltName: Full=Delta-globin; AltName: Full=Hemoglobin delta chain >gi|342834|gb|AAA36932.1| delta-globin [Pongo pygmaeus] >gi|18462036|gb|AAL72101.1| delta-globin [Pan troglodytes] 100 3.00E-56 sp|P61774|HBD_HYLLA Hemoglobin subunit delta OS=Hylobates lar GN=HBD PE=1 SV=2 100 5.00E-54 G1S6C5 G1S6C5_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=ENSG00000223609 PE=3 SV=1 - - - - - - - K13823|1|2e-56|216|hsa:3045|hemoglobin subunit beta GO:0015671//oxygen transport;GO:0007596//blood coagulation GO:0005344//oxygen transporter activity;GO:0005506//iron ion binding;GO:0020037//heme binding;GO:0019825//oxygen binding GO:0005833//hemoglobin complex 752 sp|Q07507|DERM_HUMAN Dermatopontin OS=Homo sapiens GN=DPT PE=2 SV=2 26080 MDLSLLWVLLPLVTMAWGQYGDYGYPYQQYHDYSDDGWVNLNRQGFSYQCPQGQVIVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWLTTEYPGHYGEEMDMISYNYDYYIRGATTTFSAVERDRQWKFIMCRMTEYDCEFANV 34 4 - 2 2 1 1 1.792 1.307 1.479 2 2 2 - - * 1.526 0.245892253 sp|Q07507|DERM_HUMAN 100 3.00E-97 gi|32307172|ref|NP_001928.2| dermatopontin precursor [Homo sapiens] >gi|27151769|sp|Q07507.2|DERM_HUMAN RecName: Full=Dermatopontin; AltName: Full=Tyrosine-rich acidic matrix protein; Short=TRAMP; Flags: Precursor >gi|119611236|gb|EAW90830.1| dermatopontin [Homo sapiens] 100 4.00E-98 sp|Q07507|DERM_HUMAN Dermatopontin OS=Homo sapiens GN=DPT PE=2 SV=2 100 9.00E-97 G1RY31 G1RY31_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=DPT PE=4 SV=1 - - - - - - - - GO:0008285//negative regulation of cell proliferation;GO:0007155//cell adhesion;GO:0030199//collagen fibril organization - GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix 753 tr|Q6FHG6|Q6FHG6_HUMAN PRELP protein (Fragment) OS=Homo sapiens GN=PRELP PE=2 SV=1 48717 MRSPLCWLLPLLILASVAQGQPTRRPRPGTGPGRRPRPRPRPTPSFPQPDEPAEPTDLPPPLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQSNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLDLMMCFRLLQSVVI 321 25.4 1 26 26 8 8 1.691 1.478 1 7 9 9 * - - 1.389666667 0.353867678 tr|Q6FHG6|Q6FHG6_HUMAN 100 2.00E-115 gi|33338222|gb|AAQ13708.1|AF190164_1 MSTP161 [Homo sapiens] 99.74 9.00E-174 sp|P51888|PRELP_HUMAN Prolargin OS=Homo sapiens GN=PRELP PE=1 SV=1 100 7.00E-173 Q6FHG6 Q6FHG6_HUMAN PRELP protein (Fragment) OS=Homo sapiens GN=PRELP PE=2 SV=1 alr0124_1 95.5 1.00E-19 COG4886 Leucine-rich repeat (LRR) protein S Function unknown ; K08125|1|9e-174|609|ptr:469649|proline arginine-rich end leucine-rich repeat protein GO:0005975//carbohydrate metabolic process;GO:0042340//keratan sulfate catabolic process;GO:0001501//skeletal system development;GO:0007569//cell aging;GO:0044281//small molecule metabolic process;GO:0018146//keratan sulfate biosynthetic process GO:0008201//heparin binding;GO:0005201//extracellular matrix structural constituent GO:0005796//Golgi lumen;GO:0043202//lysosomal lumen;GO:0005578//proteinaceous extracellular matrix 754 tr|B4DHK9|B4DHK9_HUMAN cDNA FLJ51656, highly similar to Actin-like protein 2 OS=Homo sapiens PE=2 SV=1 45868 MDLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLRDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGEIFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRGKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR 139 9.4 4 6 6 3 3 0.882 0.935 0.783 5 5 5 - - - 0.866666667 0.077151366 tr|B4DHK9|B4DHK9_HUMAN 100 0 gi|194379240|dbj|BAG58171.1| unnamed protein product [Homo sapiens] 99.12 0 sp|P61160|ARP2_HUMAN Actin-related protein 2 OS=Homo sapiens GN=ACTR2 PE=1 SV=1 100 0 B4DHK9 B4DHK9_HUMAN cDNA FLJ51656, highly similar to Actin-like protein 2 OS=Homo sapiens PE=2 SV=1 YDL029w 489 3.00E-138 COG5277 Actin and related proteins Z Cytoskeleton ; K05692|1|5e-81|301|bmy:Bm1_21705|actin beta/gamma 1 GO:0007163//establishment or maintenance of cell polarity;GO:0051321//meiotic cell cycle;GO:0030036//actin cytoskeleton organization;GO:0008356//asymmetric cell division;GO:0051653//spindle localization;GO:0006928//cellular component movement;GO:0016482//cytoplasmic transport;GO:0033206//cytokinesis after meiosis GO:0005524//ATP binding;GO:0003779//actin binding GO:0005885//Arp2/3 protein complex;GO:0042995//cell projection;GO:0030478//actin cap 755 sp|O60568|PLOD3_HUMAN Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 OS=Homo sapiens GN=PLOD3 PE=1 SV=1 93211 MTSSGPGPRFLLLLPLLLPPAASASDRPRGRDPVNPEKLLVITVATAETEGYLRFLRSAEFFNYTVRTLGLGEEWRGGDVARTVGGGQKVRWLKKEMEKYADREDMIIMFVDSYDVILAGSPTELLKKFVQSGSRLLFSAESFCWPEWGLAEQYPEVGTGKRFLNSGGFIGFATTIHQIVRQWKYKDDDDDQLFYTRLYLDPGLREKLSLNLDHKSRIFQNLNGALDEVVLKFDRNRVRIRNVAYDTLPIVVHGNGPTKLQLNYLGNYVPNGWTPEGGCGFCNQDRRTLPGGQPPPRVFLAVFVEQPTPFLPRFLQRLLLLDYPPDRVTLFLHNNEVFHEPHIADSWPQLQDHFSAVKLVGPEEALSPGEARDMAMDLCRQDPECEFYFSLDADAVLTNLQTLRILIEENRKVIAPMLSRHGKLWSNFWGALSPDEYYARSEDYVELVQRKRVGVWNVPYISQAYVIRGDTLRMELPQRDVFSGSDTDPDMAFCKSFRDKGIFLHLSNQHEFGRLLATSRYDTEHLHPDLWQIFDNPVDWKEQYIHENYSRALEGEGIVEQPCPDVYWFPLLSEQMCDELVAEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYEDQWLQLLRTYVGPMTESLFPGYHTKARAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGLDYEGGGCRFLRYDCVISSPRKGWALLHPGRLTHYHEGLPTTWGTRYIMVSFVDP 58 5.1 - 10 10 4 4 2.785 1.832 1.045 2 2 2 - - - 1.887333333 0.871318732 sp|O60568|PLOD3_HUMAN 100 0 gi|4505891|ref|NP_001075.1| procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 precursor [Homo sapiens] >gi|6093731|sp|O60568.1|PLOD3_HUMAN RecName: Full=Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3; AltName: Full=Lysyl hydroxylase 3; Short=LH3; Flags: Precursor >gi|5630086|gb|AAD45831.1|AC004876_4 lysyl hydroxylase 3 [Homo sapiens] >gi|3153235|gb|AAC39753.1| lysyl hydroxylase isoform 3 [Homo sapiens] >gi|3551836|gb|AAC34808.1| lysyl hydroxylase 3 [Homo sapiens] >gi|7546824|gb|AAF63701.1| lysyl hydroxylase 3 [Homo sapiens] >gi|15079714|gb|AAH11674.1| Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 [Homo sapiens] >gi|28975434|gb|AAO61775.1| lysyl hydroxylase 3 [Homo sapiens] >gi|119570590|gb|EAW50205.1| procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 [Homo sapiens] 100 0 sp|O60568|PLOD3_HUMAN Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 OS=Homo sapiens GN=PLOD3 PE=1 SV=1 99.73 0 Q9UG85 Q9UG85_HUMAN Putative uncharacterized protein DKFZp564O1822 (Fragment) OS=Homo sapiens GN=DKFZp564O1822 PE=2 SV=1 - - - - - - - K13646|1|0.0|1438|hsa:8985|lysyl hydroxylase/galactosyltransferase/glucosyltransferase [EC:1.14.11.4 2.4.1.50 2.4.1.66] GO:0055114//oxidation-reduction process;GO:0001886//endothelial cell morphogenesis;GO:0021915//neural tube development;GO:0060425//lung morphogenesis;GO:0006464//cellular protein modification process;GO:0030199//collagen fibril organization;GO:0001701//in utero embryonic development;GO:0008104//protein localization;GO:0048730//epidermis morphogenesis;GO:0042311//vasodilation;GO:0070831//basement membrane assembly GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0008475//procollagen-lysine 5-dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0005515//protein binding;GO:0033823//procollagen glucosyltransferase activity;GO:0050211//procollagen galactosyltransferase activity;GO:0005506//iron ion binding GO:0030867//rough endoplasmic reticulum membrane 756 tr|B4E320|B4E320_HUMAN cDNA FLJ50065, highly similar to MAM domain-containing protein 2 OS=Homo sapiens PE=2 SV=1 87439 MLLRGVLLALQALQLAGALDLPAGSCAFEESTCGFDSVLASLPWILNEEGHYIYVDTSFGKQGEKAVLLSPDLQAEEWSCLRLVYQITTSSESLSDPSQLNLYMRFEDESFDRLLWSAKEPSDSWLIASLDLQNSSKKFKILIEGVLGQGNTASIALFEIKMTTGYCIECDFEENHLCGFVNRWNPNVNWFVGGGSIRNVHSILPQDHTFKSELGHYMYVDSVYVKHFQEVAQLISPLTTAPMAGCLSFYYQIQQGNDNVFSLYTRDVAGLYEEIWKADRPGNAAWNLAEVEFNAPYPMEVIFEVAFNGPKGGYVALDDISFSPVHCQNQTELLFSAVEASCNFEQDLCNFYQDEEGPGWTRVKVKPNMYRAGDHTTGLGYYLLANTKFTSQPGYIGRLYGPSLPGNLQYCLRFHYAIYGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQAEITFKKPMPTKVVFMSLCKSFWDCGLVALDDITIQLGSCSSSEKLPPPPGECTFEQDECTFTQEKRNRSSWHRRRGETPTSYTGPKGDHTTGVGYYMYIEASHMVYGQKARLLSRPLRGVSGKHCLTFFYHMYGGGTGLLSVYLKKEEDSEESLLWRRRGEQSISWLRALIEYSCERQHQIIFEAIRGVSIRSDIAIDDVKFQAGPCGEMEDTTQQSSGYSEDLNEIEY 140 4.2 1 7 7 3 3 0.691 0.544 0.61 3 2 3 - - - 0.615 0.073627441 tr|B4E320|B4E320_HUMAN 100 1.00E-64 gi|31874793|emb|CAD98089.1| hypothetical protein [Homo sapiens] 99.7 0 sp|Q7Z304|MAMC2_HUMAN MAM domain-containing protein 2 OS=Homo sapiens GN=MAMDC2 PE=2 SV=3 100 0 B4E320 B4E320_HUMAN cDNA FLJ50065, highly similar to MAM domain-containing protein 2 OS=Homo sapiens PE=2 SV=1 - - - - - - - K08606|1|1e-21|105|hmg:100199496|meprin A, beta [EC:3.4.24.18] GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan GO:0005539//glycosaminoglycan binding GO:0005614//interstitial matrix;GO:0016020//membrane;GO:0005783//endoplasmic reticulum 757 sp|Q8TER0|SNED1_HUMAN Sushi, nidogen and EGF-like domain-containing protein 1 OS=Homo sapiens GN=SNED1 PE=2 SV=2 169461 MRHGVAWALLVAAALGLGARGVRGAVALADFYPFGAERGDAVTPKQDDGGSGLRPLSVPFPFFGAEHSGLYVNNNGIISFLKEVSQFTPVAFPIAKDRCVVAAFWADVDNRRAGDVYYREATDPAMLRRATEDVRHYFPELLDFNATWVFVATWYRVTFFGGSSSSPVNTFQTVLITDGKLSFTIFNYESIVWTTGTHASSGGNATGLGGIAAQAGFNAGDGQRYFSIPGSRTADMAEVETTTNVGVPGRWAFRIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSSHQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTASTISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTLSGLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYVINVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHLYIITSPRDGADRRWHQGGHHPRVLKNRPPPARLPELRLLNDHSAPETPTQPPRFSELVDGRGRVSARFGGSPSKAATVRSQPTASAQLENMEEAPKRVSLALQLPEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVCHHVYKRVYRVHQDICFKESCESTSLKKTPNRKQSKSQTLEKS 60 1.8 - 2 2 2 2 0.814 3.048 1.524 2 2 2 - * - 1.795333333 1.141448787 sp|Q8TER0|SNED1_HUMAN 100 0 gi|119591638|gb|EAW71232.1| hCG2013435, isoform CRA_e [Homo sapiens] 100 0 sp|Q8TER0|SNED1_HUMAN Sushi, nidogen and EGF-like domain-containing protein 1 OS=Homo sapiens GN=SNED1 PE=1 SV=2 100 0 B6ID16 B6ID16_9ZZZZ 6720455I24Rik homolog (Fragment) OS=synthetic construct GN=SNED1 PE=4 SV=2 - - - - - - - K02599|1|3e-111|404|aag:AaeL_AAEL010210|Notch GO:0007160//cell-matrix adhesion GO:0005509//calcium ion binding GO:0005576//extracellular region 758 tr|J3KSD8|J3KSD8_HUMAN Bleomycin hydrolase (Fragment) OS=Homo sapiens GN=BLMH PE=1 SV=3 37625 VDTAQRKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPESYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLEFYREHVKPLFNMEDKVVNDPRPQHKYNKLYTVEYLSNMVGGRKTLYNNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNSKLGLSDMNLYDHELVFGVSLKNMNKAERLTFGESLMTHAMTFTAVSEKV 108 9.1 3 4 4 2 2 0.93 0.899 0.817 3 3 3 - - - 0.882 0.058386642 tr|J3KSD8|J3KSD8_HUMAN 100 1.00E-46 gi|3860002|gb|AAC72951.1| unknown [Homo sapiens] 98.86 4.00E-155 sp|Q13867|BLMH_HUMAN Bleomycin hydrolase OS=Homo sapiens GN=BLMH PE=1 SV=1 98.86 1.00E-153 H2QCL2 H2QCL2_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000108578 PE=4 SV=1 SP0281 215 6.00E-56 COG3579 Aminopeptidase C E Amino acid transport and metabolism ; K01372|1|4e-155|546|hsa:642|bleomycin hydrolase [EC:3.4.22.40] GO:0000209//protein polyubiquitination;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0006508//proteolysis GO:0004180//carboxypeptidase activity;GO:0005515//protein binding;GO:0004177//aminopeptidase activity;GO:0004197//cysteine-type endopeptidase activity GO:0005634//nucleus;GO:0005829//cytosol 759 sp|P36955|PEDF_HUMAN Pigment epithelium-derived factor OS=Homo sapiens GN=SERPINF1 PE=1 SV=4 54972 MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP 1048 28 - 54 54 10 10 4.499 6.258 6.376 35 36 33 * * * 5.711 1.051279696 sp|P36955|PEDF_HUMAN 100 0 gi|39725934|ref|NP_002606.3| pigment epithelium-derived factor precursor [Homo sapiens] >gi|313104314|sp|P36955.4|PEDF_HUMAN RecName: Full=Pigment epithelium-derived factor; Short=PEDF; AltName: Full=Cell proliferation-inducing gene 35 protein; AltName: Full=EPC-1; AltName: Full=Serpin F1; Flags: Precursor >gi|12653501|gb|AAH00522.1| Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 [Homo sapiens] >gi|30583283|gb|AAP35886.1| serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 [Homo sapiens] >gi|326205160|dbj|BAJ83966.1| pigment epithelium-derived factor [Homo sapiens] >gi|326205162|dbj|BAJ83967.1| pigment epithelium-derived factor [Homo sapiens] >gi|326205164|dbj|BAJ83968.1| pigment epithelium-derived factor [Homo sapiens] 100 0 sp|P36955|PEDF_HUMAN Pigment epithelium-derived factor OS=Homo sapiens GN=SERPINF1 PE=1 SV=4 100 0 F1T092 F1T092_HUMAN Pigment epithelium-derived factor OS=Homo sapiens GN=SERPINF1 PE=2 SV=1 all0778 124 3.00E-28 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K03983|1|2e-39|164|oaa:100075734|alpha-2-antiplasmin GO:0050728//negative regulation of inflammatory response;GO:0050769//positive regulation of neurogenesis;GO:0016525//negative regulation of angiogenesis;GO:0001822//kidney development;GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis;GO:0032526//response to retinoic acid;GO:0007568//aging;GO:0007614//short-term memory;GO:0051384//response to glucocorticoid stimulus;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development GO:0004867//serine-type endopeptidase inhibitor activity GO:0005615//extracellular space;GO:0042470//melanosome;GO:0031012//extracellular matrix 760 tr|A0A087X0S5|A0A087X0S5_HUMAN Collagen alpha-1(VI) chain OS=Homo sapiens GN=COL6A1 PE=1 SV=1 126087 MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRVPSYQALLRGVFHQTVSRKVALG 10360 37.4 1 378 378 25 25 1.442 1.528 1.582 277 284 279 * - - 1.517333333 0.070606893 tr|A0A087X0S5|A0A087X0S5_HUMAN 100 1.00E-68 gi|1915900|emb|CAA67559.1| collagen VI-alpha-1 chain [Homo sapiens] 100 0 sp|P12109|CO6A1_HUMAN Collagen alpha-1(VI) chain OS=Homo sapiens GN=COL6A1 PE=1 SV=3 100 0 B4DRR8 B4DRR8_HUMAN Collagen alpha-1(VI) chain OS=Homo sapiens GN=COL6A1 PE=2 SV=1 - - - - - - - K06238|1|0.0|988|hsa:1291|collagen, type VI, alpha GO:0007411//axon guidance;GO:0070208//protein heterotrimerization;GO:0007155//cell adhesion;GO:0071230//cellular response to amino acid stimulus;GO:0030198//extracellular matrix organization GO:0048407//platelet-derived growth factor binding GO:0043234//protein complex;GO:0030133//transport vesicle;GO:0005788//endoplasmic reticulum lumen;GO:0042383//sarcolemma;GO:0005589//collagen type VI 761 tr|A0A024RA55|A0A024RA55_HUMAN Glycoprotein (Transmembrane) nmb, isoform CRA_b OS=Homo sapiens GN=GPNMB PE=4 SV=1 70646 MECLYYFLGFLLLAARLPLDAAKRFHDVLGNERPSAYMREHNQLNGWSSDENDWNEKLYPVWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIFPRCQKEDANGNIVYEKNCRNEAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGKPFPHHPGWRRWNFIYVFHTLGQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYRRHGRAYVPIAQVKDVYVVTDQIPVFVTMFQKNDRNSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVNHTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRPSKPTPSLGPAGDNPLELSRIPDENCQINRYGHFQATITIVEGILEVNIIQMTDVLMPVPWPESSLIDFVVTCQGSIPTEVCTIISDPTCEITQNTVCSPVDVDEMCLLTVRRTFNGSGTYCVNLTLGDDTSLALTSTLISVPDRDPASPLRMANSALISVGCLAIFVTVISLLVYKKHKEYNPIENSPGNVVRSKGLSVFLNRAKAVFFPGNQEKDPLLKNQEFKGVS 130 4.8 6 5 5 2 2 1.778 0.939 1.163 4 4 4 - - - 1.293333333 0.434419536 tr|A0A024RA55|A0A024RA55_HUMAN 100 0 gi|4505405|ref|NP_002501.1| transmembrane glycoprotein NMB isoform b precursor [Homo sapiens] >gi|666043|emb|CAA54044.1| NMB [Homo sapiens] >gi|11993665|gb|AAG42839.1| transmembrane glycoprotein HGFIN [Homo sapiens] >gi|51095015|gb|EAL24259.1| glycoprotein (transmembrane) nmb [Homo sapiens] >gi|119614188|gb|EAW93782.1| glycoprotein (transmembrane) nmb, isoform CRA_b [Homo sapiens] >gi|119614190|gb|EAW93784.1| glycoprotein (transmembrane) nmb, isoform CRA_b [Homo sapiens] 94.93 0 sp|Q14956|GPNMB_HUMAN Transmembrane glycoprotein NMB OS=Homo sapiens GN=GPNMB PE=1 SV=2 100 1.00E-169 B4DZS5 B4DZS5_HUMAN Uncharacterized protein OS=Homo sapiens GN=GPNMB PE=2 SV=1 - - - - - - - - GO:0008285//negative regulation of cell proliferation;GO:0007155//cell adhesion GO:0008201//heparin binding;GO:0005178//integrin binding GO:0005887//integral to plasma membrane;GO:0042470//melanosome 762 tr|A0A087X054|A0A087X054_HUMAN Hypoxia up-regulated protein 1 OS=Homo sapiens GN=HYOU1 PE=1 SV=1 126844 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL 65 5.5 4 6 6 5 5 1.196 0.999 1.018 2 2 2 - - - 1.071 0.108669223 tr|A0A087X054|A0A087X054_HUMAN 100 2.00E-62 gi|51476877|emb|CAH18405.1| hypothetical protein [Homo sapiens] 99.5 0 sp|Q9Y4L1|HYOU1_HUMAN Hypoxia up-regulated protein 1 OS=Homo sapiens GN=HYOU1 PE=1 SV=1 100 0 B7Z909 B7Z909_HUMAN Hypoxia up-regulated protein 1 OS=Homo sapiens GN=HYOU1 PE=2 SV=1 SPAC1F5.06 306 1.00E-82 COG0443 Molecular chaperone O Posttranslational modification, protein turnover, chaperones ; K09486|1|0.0|1702|pon:100173469|hypoxia up-regulated 1 GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0001666//response to hypoxia GO:0005524//ATP binding GO:0005788//endoplasmic reticulum lumen 763 tr|V9HWC6|V9HWC6_HUMAN Peptidyl-prolyl cis-trans isomerase OS=Homo sapiens GN=HEL-S-39 PE=2 SV=1 30999 MKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE 704 22.1 1 47 47 6 6 1.154 0.707 1.076 28 28 27 * * - 0.979 0.238765575 tr|V9HWC6|V9HWC6_HUMAN 100 2.00E-89 gi|1310882|pdb|1CYN|A Chain A, Cyclophilin B Complexed With [d-(Cholinylester)ser8]-Cyclosporin 100 1.00E-107 sp|P23284|PPIB_HUMAN Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens GN=PPIB PE=1 SV=2 100 4.00E-106 F7HFK5 F7HFK5_MACMU Peptidyl-prolyl cis-trans isomerase OS=Macaca mulatta GN=Mmu.2305 PE=2 SV=1 YDR304c 216 3.00E-56 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family O Posttranslational modification, protein turnover, chaperones ; K03768|1|2e-107|388|mcc:706757|peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] GO:0006457//protein folding;GO:0000413//protein peptidyl-prolyl isomerization;GO:0030198//extracellular matrix organization GO:0042277//peptide binding;GO:0051082//unfolded protein binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity GO:0005788//endoplasmic reticulum lumen;GO:0042470//melanosome 764 sp|P37837|TALDO_HUMAN Transaldolase OS=Homo sapiens GN=TALDO1 PE=1 SV=2 47118 MSSSPVKRQRMESALDQLKQFTTVVADTGDFHAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGRKLGGSQEDQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPLEDPGVKSVTKIYNYYKKFSYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLQDNAKLVPVLSAKAAQASDLEKIHLDEKSFRWLHNEDQMAVEKLSDGIRKFAADAVKLERMLTERMFNAENGK 389 24 - 23 23 8 8 0.814 0.855 0.659 9 10 10 - - * 0.776 0.103377947 sp|P37837|TALDO_HUMAN 100 6.00E-12 gi|1480787|gb|AAC51151.1| transaldolase [Homo sapiens] 100 0 sp|P37837|TALDO_HUMAN Transaldolase OS=Homo sapiens GN=TALDO1 PE=1 SV=2 100 2.00E-161 F2Z393 F2Z393_HUMAN Transaldolase OS=Homo sapiens GN=TALDO1 PE=3 SV=1 PM1602 393 2.00E-109 COG0176 Transaldolase G Carbohydrate transport and metabolism ; K00616|1|0.0|697|hsa:6888|transaldolase [EC:2.2.1.2] GO:0005999//xylulose biosynthetic process;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0019682//glyceraldehyde-3-phosphate metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006112//energy reserve metabolic process GO:0048029//monosaccharide binding;GO:0004801//sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle 765 tr|B7Z992|B7Z992_HUMAN cDNA FLJ53698, highly similar to Gelsolin OS=Homo sapiens PE=2 SV=1 93061 MVVEHPEFLKAGKEPGLQIWRVEKFDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTGERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVDPLDRAMAELAA 1854 21 - 71 71 11 11 0.952 1 0.878 58 58 58 - - - 0.943333333 0.061460014 tr|B7Z992|B7Z992_HUMAN 100 0 gi|221045102|dbj|BAH14228.1| unnamed protein product [Homo sapiens] 97.67 0 sp|P06396|GELS_HUMAN Gelsolin OS=Homo sapiens GN=GSN PE=1 SV=1 100 0 B7Z992 B7Z992_HUMAN cDNA FLJ53698, highly similar to Gelsolin OS=Homo sapiens PE=2 SV=1 - - - - - - - K05768|1|0.0|1468|hsa:2934|gelsolin GO:0051593//response to folic acid;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0014003//oligodendrocyte development;GO:0060271//cilium morphogenesis;GO:0042246//tissue regeneration;GO:0045471//response to ethanol;GO:0007568//aging;GO:0030155//regulation of cell adhesion;GO:0071276//cellular response to cadmium ion;GO:0051014//actin filament severing;GO:0016192//vesicle-mediated transport;GO:0048015//phosphatidylinositol-mediated signaling;GO:0051016//barbed-end actin filament capping GO:0005509//calcium ion binding;GO:0003779//actin binding GO:0030027//lamellipodium;GO:0015629//actin cytoskeleton;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0001726//ruffle;GO:0043234//protein complex;GO:0048471//perinuclear region of cytoplasm 766 tr|A4D1W8|A4D1W8_HUMAN Ependymin related protein 1 (Zebrafish), isoform CRA_b OS=Homo sapiens GN=UCC1 PE=4 SV=1 42233 MPPRMLVAPLPLHFLLAAVSSENRSGRRQWQQAVAAGSGPGRNSSRAIHWSLPRALVPATGTRASGSQKRQRPPKGQEALWSRPHSRHSAERAGGSHSDPGRLSAPLGLGLPSGRGRLTAMPGRAPLRTVPGALGAWLLGGLWAWTLCGLCSLGAVGAPRPCQAPQQWEGRQVMYQQSSGRNSRALLSYDGLNQRVRVLDERKALIPCKRLFEYILLYKDGVMFQIDQATKQCSKMTLTQPWDPLDIPQNSTFEDQYSIGGPQEQITVQEWSDRKSARSYETWIGIYTVKDCYPVQETFTINYSVILSTRFFDIQLGIKDPSVFTPPSTCQMAQLEKMSEDCSW 172 15.4 2 12 12 5 5 0.548 0.608 0.879 6 5 6 * * - 0.678333333 0.176352866 tr|A4D1W8|A4D1W8_HUMAN 100 4.00E-30 gi|345110633|ref|NP_001229875.2| mammalian ependymin-related protein 1 isoform 2 precursor [Homo sapiens] >gi|115111027|gb|ABI84106.1| mammalian ependymin protein 1a [Homo sapiens] 100 9.00E-116 sp|Q9UM22|EPDR1_HUMAN Mammalian ependymin-related protein 1 OS=Homo sapiens GN=EPDR1 PE=1 SV=2 100 7.00E-75 C9JYS3 C9JYS3_HUMAN Mammalian ependymin-related protein 1 OS=Homo sapiens GN=EPDR1 PE=4 SV=1 - - - - - - - - GO:0007160//cell-matrix adhesion GO:0005509//calcium ion binding GO:0005576//extracellular region;GO:0005764//lysosome 767 tr|Q53GE2|Q53GE2_HUMAN Capping protein (Actin filament) muscle Z-line, alpha 2 variant (Fragment) OS=Homo sapiens PE=2 SV=1 >tr|Q53GC7|Q53GC7_HUMAN Capping protein (Actin filament) muscle Z-line, alpha 2 variant (Fragment) OS=Homo sapiens PE=2 SV=1 39867 MADLEEQLSDEEKVRMAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA 176 21.7 1 8 4 4 3 0.849 0.802 0.579 4 4 4 - - * 0.743333333 0.144244006 tr|Q53GE2|Q53GE2_HUMAN 100 2.00E-46 gi|344255379|gb|EGW11483.1| F-actin-capping protein subunit alpha-2 [Cricetulus griseus] 99.65 2.00E-160 sp|Q2IBE7|CAZA2_GORGO F-actin-capping protein subunit alpha-2 OS=Gorilla gorilla gorilla GN=CAPZA2 PE=3 SV=3 100 2.00E-159 Q53GC7 Q53GC7_HUMAN Capping protein (Actin filament) muscle Z-line, alpha 2 variant (Fragment) OS=Homo sapiens PE=2 SV=1 - - - - - - - K10364|1|3e-160|564|mcc:704662|capping protein (actin filament) muscle Z-line, alpha GO:0048146//positive regulation of fibroblast proliferation;GO:0061180//mammary gland epithelium development;GO:0009267//cellular response to starvation;GO:0060716//labyrinthine layer blood vessel development;GO:0051899//membrane depolarization;GO:0060056//mammary gland involution;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0051450//myoblast proliferation;GO:0000188//inactivation of MAPK activity;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0046777//protein autophosphorylation;GO:0042524//negative regulation of tyrosine phosphorylation of Stat5 protein;GO:0071455//cellular response to hyperoxia;GO:0070836//caveola assembly;GO:0030534//adult behavior;GO:0032091//negative regulation of protein binding;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0006641//triglyceride metabolic process;GO:0000187//activation of MAPK activity;GO:0030193//regulation of blood coagulation;GO:0045087//innate immune response;GO:0042593//glucose homeostasis;GO:0045907//positive regulation of vasoconstriction;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0016050//vesicle organization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0014812//muscle cell migration;GO:0001937//negative regulation of endothelial cell proliferation;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0030857//negative regulation of epithelial cell differentiation;GO:0051592//response to calcium ion;GO:0001889//liver development;GO:2000286//receptor internalization involved in canonical Wnt receptor signaling pathway;GO:0060501//positive regulation of epithelial cell proliferation involved in lung morphogenesis;GO:0032570//response to progesterone stimulus;GO:0001666//response to hypoxia;GO:0033484//nitric oxide homeostasis;GO:0007420//brain development;GO:0010828//positive regulation of glucose transport;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0014902//myotube differentiation;GO:0008104//protein localization;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0090090//negative regulation of canonical Wnt receptor signaling pathway;GO:0043627//response to estrogen stimulus;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0007595//lactation;GO:0006940//regulation of smooth muscle contraction;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0019217//regulation of fatty acid metabolic process;GO:0090263//positive regulation of canonical Wnt receptor signaling pathway;GO:0051693//actin filament capping;GO:0051260//protein homooligomerization;GO:0048554//positive regulation of metalloenzyme activity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0060492//lung induction;GO:0060665//regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling;GO:0030514//negative regulation of BMP signaling pathway;GO:0072584//caveolin-mediated endocytosis;GO:0031295//T cell costimulation;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0042632//cholesterol homeostasis;GO:0001570//vasculogenesis;GO:0019915//lipid storage GO:0003779//actin binding;GO:0005008//hepatocyte growth factor-activated receptor activity;GO:0005109//frizzled binding;GO:0005198//structural molecule activity;GO:0050998//nitric-oxide synthase binding;GO:0005113//patched binding;GO:0016504//peptidase activator activity;GO:0005524//ATP binding;GO:0005125//cytokine activity GO:0008290//F-actin capping protein complex;GO:0009925//basal plasma membrane;GO:0016324//apical plasma membrane;GO:0002080//acrosomal membrane;GO:0005783//endoplasmic reticulum;GO:0005578//proteinaceous extracellular matrix;GO:0005768//endosome;GO:0030863//cortical cytoskeleton;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0005901//caveola;GO:0000139//Golgi membrane;GO:0005887//integral to plasma membrane 768 tr|J3KNQ4|J3KNQ4_HUMAN Alpha-parvin OS=Homo sapiens GN=PARVA PE=1 SV=1 56961 MLGIIPLPFGKPQPQSRRRPLRPPSASSASRPARGSLRRAMATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE 251 13.8 1 12 12 5 5 0.851 0.82 0.864 8 8 8 - - - 0.845 0.022605309 tr|J3KNQ4|J3KNQ4_HUMAN 100 0 gi|315583337|ref|NP_060692.2| alpha-parvin [Homo sapiens] >gi|119588931|gb|EAW68525.1| parvin, alpha, isoform CRA_c [Homo sapiens] 100 0 sp|Q9NVD7|PARVA_HUMAN Alpha-parvin OS=Homo sapiens GN=PARVA PE=1 SV=1 100 0 F6T6X4 F6T6X4_CALJA Uncharacterized protein OS=Callithrix jacchus GN=LOC100395254 PE=4 SV=1 - - - - - - - K06275|1|0.0|706|hsa:55742|parvin GO:0060271//cilium morphogenesis;GO:0051291//protein heterooligomerization;GO:0030036//actin cytoskeleton organization;GO:0007155//cell adhesion;GO:0034329//cell junction assembly GO:0003779//actin binding GO:0005829//cytosol;GO:0043234//protein complex;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0030027//lamellipodium;GO:0005634//nucleus 769 tr|A0A087WUL2|A0A087WUL2_HUMAN Proteasome subunit beta type-3 (Fragment) OS=Homo sapiens GN=PSMB3 PE=1 SV=1 19420 MSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYG 112 11 1 5 5 1 1 1.186 0.564 0.6 3 3 3 - - - 0.783333333 0.34918381 tr|A0A087WUL2|A0A087WUL2_HUMAN 100 2.00E-22 gi|344235158|gb|EGV91261.1| Proteasome subunit beta type-3 [Cricetulus griseus] 100 3.00E-82 sp|P49720|PSB3_HUMAN Proteasome subunit beta type-3 OS=Homo sapiens GN=PSMB3 PE=1 SV=2 100 9.00E-81 F7EIY0 F7EIY0_MACMU Proteasome subunit beta type OS=Macaca mulatta GN=PSMB3 PE=2 SV=1 YER094c 156 1.00E-38 COG0638 20S proteasome, alpha and beta subunits O Posttranslational modification, protein turnover, chaperones ; K02735|1|3e-82|303|mcc:694318|20S proteasome subunit beta 3 [EC:3.4.25.1] GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0019048//virus-host interaction;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0004298//threonine-type endopeptidase activity GO:0005654//nucleoplasm;GO:0005839//proteasome core complex;GO:0005829//cytosol 770 tr|B2RAR6|B2RAR6_HUMAN cDNA, FLJ95068, highly similar to Homo sapiens eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) (EEF1D), transcript variant 1, mRNA OS=Homo sapiens PE=2 SV=1 83726 MRSGKASCTLETVWEDKHKYEEAERRFYEHEATQAAASAQQLPAEGPAMNGPGQDDPEDADEAEAPDGGSRRDPRKSQDSRKPLQKKRKRSPKSGLGPVDLALLGLSAERVWLDKSLFDQAESSYRQKLADVAAQAAWPPALAPWGLCTHGNQVACHHVTWGIWVNKSSFDQAERAFVEWSQALLLAPEGSRRQGTPNTGQQVAVPDLAHQPSPPVNGQPPLGSLQALVREVWLEKPRYDAAERGFYEALFDGHPPGKVRLQERAGLAEGARRGRRDRRGRNILGNKRAGLRRADGEAPSALPYCYFLQKDAEAPWLSKPAYDSAECRHHAAEALRVAWCLEAASLSHRPGPRSGLSVSSLRPNRKMATNFLAHEKIWFDKFKYDDAERRFYEQMNGPVAGASRQENGASVILRDIARARENIQKSLAGSSGPGASSGTSGDHGELVVRIASLEVENQSLRGVVQELQQAISKLEARLNVLEKSSPGHRATAPQTQHVSPMRQVEPPAKKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDVKPWDDETDMAQLEACVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEEITKFEEHVQSVDIAAFNKI 283 7.6 4 10 10 4 4 1.043 0.993 1.163 9 9 9 - - - 1.066333333 0.087368949 tr|B2RAR6|B2RAR6_HUMAN 100 0 gi|189067253|dbj|BAG36963.1| unnamed protein product [Homo sapiens] 100 4.00E-138 sp|P29692|EF1D_HUMAN Elongation factor 1-delta OS=Homo sapiens GN=EEF1D PE=1 SV=5 100 6.00E-108 H0YCK7 H0YCK7_HUMAN Elongation factor 1-delta (Fragment) OS=Homo sapiens GN=EEF1D PE=4 SV=1 SPCC1450.04 147 6.00E-35 COG2092 Translation elongation factor EF-1beta J Translation, ribosomal structure and biogenesis ; K15410|1|0.0|1092|hsa:1936|elongation factor 1-delta GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB cascade;GO:0006414//translational elongation GO:0003746//translation elongation factor activity;GO:0004871//signal transducer activity;GO:0005515//protein binding GO:0005853//eukaryotic translation elongation factor 1 complex;GO:0005829//cytosol 771 tr|D3DT71|D3DT71_HUMAN Collagen, type XI, alpha 1, isoform CRA_b OS=Homo sapiens GN=COL11A1 PE=4 SV=1 209394 MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGPPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFLG 542 9.2 2 28 21 10 9 1.061 1.076 0.886 8 9 9 - - - 1.007666667 0.105633013 tr|D3DT71|D3DT71_HUMAN 100 1.00E-57 gi|6165883|gb|AAF04726.1| collagen type XI alpha-a isoform B [Homo sapiens] 100 1.00E-09 sp|P12107|COBA1_HUMAN Collagen alpha-1(XI) chain OS=Homo sapiens GN=COL11A1 PE=1 SV=4 100 3.00E-08 G1N4L1 G1N4L1_MELGA Uncharacterized protein (Fragment) OS=Meleagris gallopavo GN=COL11A1 PE=4 SV=2 - - - - - - - K06236|1|0.0|777|hsa:1301|collagen, type I/II/III/V/XI, alpha GO:0030199//collagen fibril organization;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0007601//visual perception GO:0050840//extracellular matrix binding;GO:0030674//protein binding, bridging;GO:0005201//extracellular matrix structural constituent GO:0005788//endoplasmic reticulum lumen;GO:0005592//collagen type XI 772 sp|Q7Z7M9|GALT5_HUMAN Polypeptide N-acetylgalactosaminyltransferase 5 OS=Homo sapiens GN=GALNT5 PE=1 SV=1 132304 MNRIRKFFRGSGRVLAFIFVASVIWLLFDMAALRLSFSEINTRVIKEDIVRRERIGFRVQPDQGKIFYSSIKEMKPPLRGHGKGAWGKENVRKTEESVLKVEVDLDQTQRERKMQNALGRGKVVPLWHPAHLQTLPVTPNKQKTDGRGTKPEASSHQGTPKQTTAQGAPKTSFIAAKGTQVVKISVHMGRVSLKQEPRKSHSPSSDTSKLAAERDLNVTISLSTDRPKQRSQAVANERAHPASTAVPKSGEAMALNKTKTQSKEVNANKHKANTSLPFPKFTVNSNRLRKQSINETPLGSLSKDDGARGAHGKKLNFSESHLVIITKEEEQKADPKEVSNSKTKTIFPKVLGKSQSKHISRNRSEMSSSSLAPHRVPLSQTNHALTGGLEPAKINITAKAPSTEYNQSHIKALLPEDSGTHQVLRIDVTLSPRDPKAPGQFGRPVVVPHGKEKEAERRWKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHNNLPTTSVIMCFVDEVWSTLLRSVHSVINRSPPHLIKEILLVDDFSTKDYLKDNLDKYMSQFPKVRILRLKERHGLIRARLAGAQNATGDVLTFLDSHVECNVGWLEPLLERVYLSRKKVACPVIEVINDKDMSYMTVDNFQRGIFVWPMNFGWRTIPPDVIAKNRIKETDTIRCPVMAGGLFSIDKSYFFELGTYDPGLDVWGGENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMKTVERNLVRVAEVWLDEYKELFYGHGDHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLENVFPDLRAPIVRASGVLINVALGKCISIENTTVILEDCDGSKELQQFNYTWLRLIKCGEWCIAPIPDKGAVRLHPCDNRNKGLKWLHKSTSVFHPELVNHIVFENNQQLLCLEGNFSQKILKVAACDPVKPYQKWKFEKYYEA 248 5.7 - 11 11 5 5 0.863 0.556 0.632 6 6 6 - * * 0.683666667 0.159888503 sp|Q7Z7M9|GALT5_HUMAN 100 0 gi|6688167|emb|CAB65104.1| GalNAc-T5 [Homo sapiens] 100 0 sp|Q7Z7M9|GALT5_HUMAN Polypeptide N-acetylgalactosaminyltransferase 5 OS=Homo sapiens GN=GALNT5 PE=1 SV=1 100 0 A5PKZ1 A5PKZ1_HUMAN UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) OS=Homo sapiens GN=GALNT5 PE=2 SV=1 - - - - - - - K00710|1|0.0|1929|hsa:11227|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0006024//glycosaminoglycan biosynthetic process GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0030246//carbohydrate binding GO:0000139//Golgi membrane;GO:0016021//integral to membrane 773 tr|A1XP52|A1XP52_HUMAN Catecholamine-regulated protein 40 OS=Homo sapiens PE=2 SV=1 47970 MDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGRERQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEGFKDQLPADECNKLKEEISKMRELLARKDSEKDSETGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEKQ 139 7.4 5 7 7 2 2 0.686 1.504 1.32 4 3 2 - - - 1.17 0.429134012 tr|A1XP52|A1XP52_HUMAN 100 4.00E-168 gi|94450030|gb|ABF19573.1| catecholamine-regulated protein 40 [Homo sapiens] 98.17 1.00E-163 sp|P38646|GRP75_HUMAN Stress-70 protein, mitochondrial OS=Homo sapiens GN=HSPA9 PE=1 SV=2 100 1.00E-167 A1XP52 A1XP52_HUMAN Catecholamine-regulated protein 40 OS=Homo sapiens PE=2 SV=1 SMc02857 408 6.00E-114 COG0443 Molecular chaperone O Posttranslational modification, protein turnover, chaperones ; K04043|1|8e-164|576|mcc:714506|molecular chaperone DnaK GO:0006457//protein folding;GO:0006611//protein export from nucleus;GO:0006626//protein targeting to mitochondrion GO:0005524//ATP binding;GO:0051082//unfolded protein binding GO:0005730//nucleolus;GO:0042645//mitochondrial nucleoid;GO:0009986//cell surface 774 sp|P27487|DPP4_HUMAN Dipeptidyl peptidase 4 OS=Homo sapiens GN=DPP4 PE=1 SV=2 101379 MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP 63 8.2 - 8 8 6 6 0.974 0.8 0.796 2 2 2 - - - 0.856666667 0.101633328 sp|P27487|DPP4_HUMAN 100 0 gi|50513374|pdb|1R9M|A Chain A, Crystal Structure Of Human Dipeptidyl Peptidase Iv At 2.1 Ang. Resolution. >gi|50513375|pdb|1R9M|B Chain B, Crystal Structure Of Human Dipeptidyl Peptidase Iv At 2.1 Ang. Resolution. >gi|50513376|pdb|1R9M|C Chain C, Crystal Structure Of Human Dipeptidyl Peptidase Iv At 2.1 Ang. Resolution. >gi|50513377|pdb|1R9M|D Chain D, Crystal Structure Of Human Dipeptidyl Peptidase Iv At 2.1 Ang. Resolution 100 0 sp|P27487|DPP4_HUMAN Dipeptidyl peptidase 4 OS=Homo sapiens GN=DPP4 PE=1 SV=2 99.61 0 H2R124 H2R124_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000197635 PE=4 SV=1 SPACUNK4.08 338 2.00E-92 COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases E Amino acid transport and metabolism ; K01278|1|0.0|1554|hsa:1803|dipeptidyl-peptidase 4 [EC:3.4.14.5] GO:0051234//establishment of localization;GO:0043542//endothelial cell migration;GO:0031295//T cell costimulation;GO:0033632//regulation of cell-cell adhesion mediated by integrin;GO:0002709//regulation of T cell mediated immunity;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0008284//positive regulation of cell proliferation;GO:0001666//response to hypoxia;GO:0006508//proteolysis GO:0005102//receptor binding;GO:0008239//dipeptidyl-peptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0042277//peptide binding;GO:0002020//protease binding;GO:0042803//protein homodimerization activity;GO:0005518//collagen binding;GO:0004177//aminopeptidase activity GO:0045121//membrane raft;GO:0071438//invadopodium membrane;GO:0016021//integral to membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0009986//cell surface;GO:0030139//endocytic vesicle;GO:0031258//lamellipodium membrane;GO:0005783//endoplasmic reticulum;GO:0046581//intercellular canaliculus;GO:0016324//apical plasma membrane 775 tr|H0Y7A7|H0Y7A7_HUMAN Calmodulin (Fragment) OS=Homo sapiens GN=CALM2 PE=1 SV=1 24209 SPSGESELSGCVVASRKPVALAAWLALYIASHFAQQPCKADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 201 9.1 9 15 15 2 2 0.653 0.603 0.592 8 8 8 * - * 0.616 0.032511536 tr|H0Y7A7|H0Y7A7_HUMAN 100 2.00E-74 gi|225705998|gb|ACO08845.1| Calmodulin-alpha [Osmerus mordax] 100 5.00E-81 sp|P62149|CALM_CHICK Calmodulin OS=Gallus gallus GN=CALM PE=1 SV=2 100 1.00E-79 H0WZA4 H0WZA4_OTOGA Uncharacterized protein OS=Otolemur garnettii GN=CALM1 PE=4 SV=1 SPAC3A12.14 235 4.00E-62 COG5126 Ca2+-binding protein (EF-Hand superfamily) TZDR Signal transduction mechanisms ; Cytoskeleton ; Cell cycle control, cell division, chromosome partitioning ; General function prediction only ; K02183|1|3e-82|304|ecb:100071150|calmodulin GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0006006//glucose metabolic process;GO:0050804//regulation of synaptic transmission;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006470//protein dephosphorylation;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0030168//platelet activation;GO:0007202//activation of phospholipase C activity;GO:0051592//response to calcium ion;GO:0032465//regulation of cytokinesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0044281//small molecule metabolic process;GO:0006936//muscle contraction;GO:0048741//skeletal muscle fiber development;GO:0002576//platelet degranulation;GO:0006606//protein import into nucleus;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0046209//nitric oxide metabolic process;GO:0014883//transition between fast and slow fiber;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0033173//calcineurin-NFAT signaling cascade;GO:0005980//glycogen catabolic process;GO:0050999//regulation of nitric-oxide synthase activity;GO:0008543//fibroblast growth factor receptor signaling pathway GO:0043548//phosphatidylinositol 3-kinase binding;GO:0031997//N-terminal myristoylation domain binding;GO:0019904//protein domain specific binding;GO:0031432//titin binding;GO:0048306//calcium-dependent protein binding;GO:0031996//thioesterase binding;GO:0043274//phospholipase binding;GO:0005516//calmodulin binding;GO:0033192//calmodulin-dependent protein phosphatase activity;GO:0005509//calcium ion binding GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005955//calcineurin complex;GO:0005876//spindle microtubule;GO:0005886//plasma membrane;GO:0000922//spindle pole;GO:0005739//mitochondrion;GO:0030018//Z disc;GO:0005813//centrosome;GO:0005576//extracellular region 776 tr|A0A024RDE6|A0A024RDE6_HUMAN Secreted phosphoprotein 1 (Osteopontin, bone sialoprotein I, early T-lymphocyte activation 1), isoform CRA_c OS=Homo sapiens GN=SPP1 PE=4 SV=1 39774 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQTLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN 106 11 4 5 5 2 2 1.967 0.724 1.311 2 2 2 - - - 1.334 0.621819106 tr|A0A024RDE6|A0A024RDE6_HUMAN 100 6.00E-131 gi|4759166|ref|NP_000573.1| osteopontin isoform OPN-b precursor [Homo sapiens] >gi|189405|gb|AAA59974.1| osteopontin [Homo sapiens] >gi|3360432|gb|AAC28619.1| osteopontin [Homo sapiens] >gi|13937829|gb|AAH07016.1| Secreted phosphoprotein 1 [Homo sapiens] >gi|18606299|gb|AAH22844.1| Secreted phosphoprotein 1 [Homo sapiens] >gi|119626411|gb|EAX06006.1| secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1), isoform CRA_c [Homo sapiens] >gi|119626414|gb|EAX06009.1| secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1), isoform CRA_c [Homo sapiens] 95.54 3.00E-129 sp|P10451|OSTP_HUMAN Osteopontin OS=Homo sapiens GN=SPP1 PE=1 SV=1 96.33 6.00E-124 Q5R8A7 Q5R8A7_PONAB Putative uncharacterized protein DKFZp469P2134 OS=Pongo abelii GN=DKFZp469P2134 PE=2 SV=1 - - - - - - - K06250|1|8e-132|469|hsa:6696|secreted phosphoprotein 1 GO:0048685//negative regulation of collateral sprouting of intact axon in response to injury;GO:0030593//neutrophil chemotaxis;GO:0001649//osteoblast differentiation;GO:0031214//biomineral tissue development;GO:0045780//positive regulation of bone resorption;GO:0033280//response to vitamin D;GO:0048545//response to steroid hormone stimulus;GO:0046697//decidualization;GO:0007566//embryo implantation;GO:0006954//inflammatory response;GO:0010811//positive regulation of cell-substrate adhesion GO:0050840//extracellular matrix binding;GO:0005125//cytokine activity GO:0031988//membrane-bounded vesicle;GO:0005615//extracellular space;GO:0042995//cell projection;GO:0045177//apical part of cell;GO:0048471//perinuclear region of cytoplasm 777 tr|H0UI49|H0UI49_HUMAN Laminin, alpha 4, isoform CRA_b OS=Homo sapiens GN=LAMA4 PE=4 SV=1 235901 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDDLRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNHVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSSGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCPAA 1738 21 1 93 93 29 29 1.374 1.487 1.711 56 57 56 * * * 1.524 0.171519678 tr|H0UI49|H0UI49_HUMAN 100 0 gi|119568652|gb|EAW48267.1| laminin, alpha 4, isoform CRA_b [Homo sapiens] >gi|119568654|gb|EAW48269.1| laminin, alpha 4, isoform CRA_b [Homo sapiens] 99.45 0 sp|Q16363|LAMA4_HUMAN Laminin subunit alpha-4 OS=Homo sapiens GN=LAMA4 PE=1 SV=4 100 0 H0UI49 H0UI49_HUMAN Laminin, alpha 4, isoform CRA_b OS=Homo sapiens GN=LAMA4 PE=4 SV=1 - - - - - - - K06241|1|0.0|3715|hsa:3910|laminin, alpha 4 GO:0030334//regulation of cell migration;GO:0045995//regulation of embryonic development;GO:0030155//regulation of cell adhesion;GO:0001568//blood vessel development;GO:0050873//brown fat cell differentiation GO:0005201//extracellular matrix structural constituent;GO:0005102//receptor binding GO:0005606//laminin-1 complex 778 sp|Q9BZQ8|NIBAN_HUMAN Protein Niban OS=Homo sapiens GN=FAM129A PE=1 SV=1 >tr|A0A024R978|A0A024R978_HUMAN Chromosome 1 open reading frame 24, isoform CRA_a OS=Homo sapiens GN=C1orf24 PE=4 SV=1 121683 MGGSASSQLDEGKCAYIRGKTEAAIKNFSPYYSRQYSVAFCNHVRTEVEQQRDLTSQFLKTKPPLAPGTILYEAELSQFSEDIKKWKERYVVVKNDYAVESYENKEAYQRGAAPKCRILPAGGKVLTSEDEYNLLSDRHFPDPLASSEKENTQPFVVLPKEFPVYLWQPFFRHGYFCFHEAADQKRFSALLSDCVRHLNHDYMKQMTFEAQAFLEAVQFFRQEKGHYGSWEMITGDEIQILSNLVMEELLPTLQTDLLPKMKGKKNDRKRTWLGLLEEAYTLVQHQVSEGLSALKEECRALTKGLEGTIRSDMDQIVNSKNYLIGKIKAMVAQPAEKSCLESVQPFLASILEELMGPVSSGFSEVRVLFEKEVNEVSQNFQTTKDSVQLKEHLDRLMNLPLHSVKMEPCYTKVNLLHERLQDLKSRFRFPHIDLVVQRTQNYMQELMENAVFTFEQLLSPHLQGEASKTAVAIEKVKLRVLKQYDYDSSTIRKKIFQEALVQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVENVYEEILHQILLDETLKVIKEAAILKKHNLFEDNMALPSESVSSLTDLKPPTGSNQASPARRASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLAKGESLSLPGPSPPPDGTEQVIISRVDDPVVNPVATEDTAGLPGTCSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDPICLSESQVSEEQEEMGGQSSAAQATASVNAEEIKVARIHECQWVVEDAPNPDVLLSHKDDVKEGEGGQESFPELPSEE 69 2.3 - 2 2 2 2 1.729 1.309 1.108 2 2 2 - - - 1.382 0.316870636 sp|Q9BZQ8|NIBAN_HUMAN 100 0 gi|16757970|ref|NP_443198.1| protein Niban isoform 2 [Homo sapiens] >gi|22256936|sp|Q9BZQ8.1|NIBAN_HUMAN RecName: Full=Protein Niban; AltName: Full=Cell growth-inhibiting gene 39 protein; AltName: Full=Protein FAM129A >gi|12620192|gb|AAG60611.1|AF288391_1 C1orf24 [Homo sapiens] >gi|20988569|gb|AAH30531.1| Family with sequence similarity 129, member A [Homo sapiens] >gi|119611590|gb|EAW91184.1| chromosome 1 open reading frame 24, isoform CRA_a [Homo sapiens] >gi|119611591|gb|EAW91185.1| chromosome 1 open reading frame 24, isoform CRA_a [Homo sapiens] 100 0 sp|Q9BZQ8|NIBAN_HUMAN Protein Niban OS=Homo sapiens GN=FAM129A PE=1 SV=1 100 3.00E-41 Q5TEY9 Q5TEY9_HUMAN Family with sequence similarity 129, member A (Fragment) OS=Homo sapiens GN=FAM129A PE=2 SV=1 - - - - - - - - GO:0034976//response to endoplasmic reticulum stress;GO:0001933//negative regulation of protein phosphorylation;GO:0045727//positive regulation of translation;GO:0001934//positive regulation of protein phosphorylation - GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005886//plasma membrane 779 tr|A0A087WZM2|A0A087WZM2_HUMAN Ribonuclease T2 OS=Homo sapiens GN=RNASET2 PE=1 SV=1 42033 MRPAALRGALLGCLCLALLCLGGADKRLRDNHEWKKLIMVQHWPETVCEKIQNDCRDPPDYWTIHGLWPDKSEGCNRSWPFNLEEIKVLTFNYISTAECSSHRLSSSPPGLTAGNGFWGGSEERCGRGWPMFLEQIKDLLPEMRAYWPDVIHSFPNRSRFWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSINYYQVADFKDALARVYGVIPKIQCLPPSQDEEVQTIGQIELCLTKQDQQLQNCTEPGEQPSPKQEVWLANGAAESRGLRVCEDGPVFYPPPKKTKH 79 3.3 5 3 3 1 1 2.485 3.184 2.103 2 2 2 - * - 2.590666667 0.548191876 tr|A0A087WZM2|A0A087WZM2_HUMAN 100 3.00E-92 gi|119567896|gb|EAW47511.1| ribonuclease T2, isoform CRA_a [Homo sapiens] 76.24 4.00E-117 sp|O00584|RNT2_HUMAN Ribonuclease T2 OS=Homo sapiens GN=RNASET2 PE=1 SV=2 99.29 4.00E-164 G3QE07 G3QE07_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=ENSG00000026297 PE=3 SV=1 - - - - - - - K01166|1|5e-117|421|hsa:8635|ribonuclease T2 [EC:3.1.27.1] GO:0006401//RNA catabolic process GO:0004540//ribonuclease activity - 780 tr|Q5PY49|Q5PY49_HUMAN Urokinase plasminogen activator (Fragment) OS=Homo sapiens PE=1 SV=1 56224 SNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL 257 18.7 2 22 22 7 7 0.912 0.737 0.913 4 9 8 * - - 0.854 0.101326206 tr|Q5PY49|Q5PY49_HUMAN 100 8.00E-69 gi|90109323|pdb|2FD6|A Chain A, Structure Of Human Urokinase Plasminogen Activator In Complex With Urokinase Receptor And An Anti-Upar Antibody At 1.9 A 100 0 sp|P00749|UROK_HUMAN Urokinase-type plasminogen activator OS=Homo sapiens GN=PLAU PE=1 SV=2 100 0 Q5PY49 Q5PY49_HUMAN Urokinase plasminogen activator (Fragment) OS=Homo sapiens PE=2 SV=1 VC1649 97.1 5.00E-20 COG5640 Secreted trypsin-like serine protease O Posttranslational modification, protein turnover, chaperones ; K01348|1|0.0|862|ptr:738078|urokinase plasminogen activator [EC:3.4.21.73] GO:0001666//response to hypoxia;GO:0001525//angiogenesis;GO:2000097//regulation of smooth muscle cell-matrix adhesion;GO:0007566//embryo implantation;GO:0043403//skeletal muscle tissue regeneration;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0014910//regulation of smooth muscle cell migration;GO:0042730//fibrinolysis;GO:0006935//chemotaxis;GO:0006508//proteolysis;GO:0042127//regulation of cell proliferation;GO:0010469//regulation of receptor activity;GO:0055093//response to hyperoxia GO:0005515//protein binding;GO:0016301//kinase activity;GO:0004252//serine-type endopeptidase activity GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005886//plasma membrane