Hits Accession Desription Mass Seq Score Cov SameSets Spectrum Unique Spectrum Peptide Unique Peptide DP9-VS-DP3@Ratio@set1,DP9_1_114-VS-DP3_1_113 DP9-VS-DP3@Ratio@set1,DP9_2_117-VS-DP3_2_115 DP9-VS-DP3@Ratio@set1,DP9_3_121-VS-DP3_3_118 DP9-VS-DP3@QuantNumber@set1,DP9_1_114-VS-DP3_1_113 DP9-VS-DP3@QuantNumber@set1,DP9_2_117-VS-DP3_2_115 DP9-VS-DP3@QuantNumber@set1,DP9_3_121-VS-DP3_3_118 DP9-VS-DP3@Sig@set1,DP9_1_114-VS-DP3_1_113 DP9-VS-DP3@Sig@set1,DP9_2_117-VS-DP3_2_115 DP9-VS-DP3@Sig@set1,DP9_3_121-VS-DP3_3_118 DP9-VS-DP3@Mean DP9-VS-DP3@SD Accession NCBInr Identity NCBInr E_Value NCBInr Accession NCBInr Description Uniprot_Swissprot Identity Uniprot_Swissprot E_Value Uniprot_Swissprot Accession Uniprot_Swissprot Description Uniprot_Tremble Identity Uniprot_Tremble E_Value Uniprot_Tremble Accession Uniprot_Tremble Description Protein_or_Domain COG Identity COG E-Value COG_ID COG Function-Description COG Code COG Functional-Categories KEGG(ko_id|rank|evalue|score|identity|ko_definition) GO Biological_Process GO Molecular_Function GO Cellular_Component 1 sp|P35555|FBN1_HUMAN Fibrillin-1 OS=Homo sapiens GN=FBN1 PE=1 SV=3 366735 MRRGRLLEIALGFTVLLASYTSHGADANLEAGNVKETRASRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYECKINGYPKRGRKRRSTNETDASNIEDQSETEANVSLASWDVEKTAIFAFNISHVSNKVRILELLPALTTLTNHNRYLIESGNEDGFFKINQKEGISYLHFTKKKPVAGTYSLQISSTPLYKKKELNQLEDKYDKDYLSGELGDNLKMKIQVLLH 2546 17.1 - 125 116 35 34 0.859 0.645 0.685 86 86 87 * * * 0.729666666666667 0.113777560763682 sp|P35555|FBN1_HUMAN 100.00 0.0 gi|311033452|sp|P35555.3|FBN1_HUMAN RecName: Full=Fibrillin-1; Flags: Precursor 100.00 0.0 sp|P35555|FBN1_HUMAN Fibrillin-1 OS=Homo sapiens GN=FBN1 PE=1 SV=3 100.00 0.0 H0YND0 H0YND0_HUMAN Fibrillin-1 (Fragment) OS=Homo sapiens GN=FBN1 PE=4 SV=1 - - - - - - - K06825|1|0.0|5573|hsa:2200|fibrillin 1 GO:0035582//sequestering of BMP in extracellular matrix;GO:0007507//heart development;GO:0001501//skeletal system development;GO:0035583//sequestering of TGFbeta in extracellular matrix GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0001527//microfibril 2 tr|J3QS39|J3QS39_HUMAN Ubiquitin (Fragment) OS=Homo sapiens GN=UBB PE=4 SV=1 13505 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEV 420 36.6 30 22 22 3 3 0.769 0.603 0.700 8 9 9 * * * 0.690666666666667 0.083392645559026 tr|J3QS39|J3QS39_HUMAN 100.00 1e-36 gi|24640086|ref|NP_727078.1| Ubiquitin-5E [Drosophila melanogaster] >gi|194896187|ref|XP_001978429.1| GG17684 [Drosophila erecta] >gi|22831806|gb|AAF46142.3| Ubiquitin-5E [Drosophila melanogaster] >gi|190650078|gb|EDV47356.1| GG17684 [Drosophila erecta] >gi|208879484|gb|ACI31287.1| GH17761p [Drosophila melanogaster] 100.00 7e-47 sp|P0CG50|UBC_MOUSE Polyubiquitin-C OS=Mus musculus GN=Ubc PE=1 SV=2 100.00 3e-45 Q5CKW6 Q5CKW6_CRYHO Ubiquitin B OS=Cryptosporidium hominis GN=Chro.50123 PE=4 SV=1 YLL039c 180 5e-46 COG5272 Ubiquitin O Posttranslational modification, protein turnover, chaperones ; K08770|1|5e-47|186|dya:Dyak_GE18016|ubiquitin C - - 3 tr|F6RFD5|F6RFD5_HUMAN Destrin OS=Homo sapiens GN=DSTN PE=1 SV=1 22117 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASSKDAIKKKFQGKCTHS 163 20.7 1 13 13 4 4 0.522 0.522 0.388 6 6 6 * * * 0.477333333333333 0.0773649360714099 tr|F6RFD5|F6RFD5_HUMAN 100.00 7e-59 gi|58530848|ref|NP_001011546.1| destrin isoform b [Homo sapiens] >gi|119630679|gb|EAX10274.1| destrin (actin depolymerizing factor), isoform CRA_a [Homo sapiens] >gi|119630681|gb|EAX10276.1| destrin (actin depolymerizing factor), isoform CRA_a [Homo sapiens] >gi|444729534|gb|ELW69947.1| Destrin [Tupaia chinensis] 100.00 2e-70 sp|P60982|DEST_PIG Destrin OS=Sus scrofa GN=DSTN PE=1 SV=3 100.00 3e-68 H0V5S5 H0V5S5_CAVPO Uncharacterized protein (Fragment) OS=Cavia porcellus GN=DSTN PE=4 SV=1 - - - - - - - K10363|1|4e-71|265|ptr:458108|destrin (actin-depolymerizing factor) GO:0030836//positive regulation of actin filament depolymerization;GO:0000910//cytokinesis;GO:0051014//actin filament severing;GO:0006928//cellular component movement GO:0003779//actin binding GO:0030864//cortical actin cytoskeleton 4 sp|Q08629|TICN1_HUMAN Testican-1 OS=Homo sapiens GN=SPOCK1 PE=1 SV=1 62078 MPAIAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDKYWNRFRDDDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFDTSILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRAVTEDDEDEDDDKEDEVGYIW 178 12.8 - 13 13 5 5 0.744 0.593 0.556 10 10 10 * * * 0.631 0.0995941765365827 sp|Q08629|TICN1_HUMAN 100.00 0.0 gi|4759164|ref|NP_004589.1| testican-1 precursor [Homo sapiens] >gi|24212472|sp|Q08629.1|TICN1_HUMAN RecName: Full=Testican-1; AltName: Full=Protein SPOCK; Flags: Precursor >gi|7248845|gb|AAF43687.1|AF231124_1 testican-1 [Homo sapiens] >gi|793845|emb|CAA51999.1| testican [Homo sapiens] 100.00 0.0 sp|Q08629|TICN1_HUMAN Testican-1 OS=Homo sapiens GN=SPOCK1 PE=1 SV=1 100.00 8e-70 D6RB21 D6RB21_HUMAN Testican-1 (Fragment) OS=Homo sapiens GN=SPOCK1 PE=4 SV=1 - - - - - - - K08136|1|0.0|828|hsa:6695|sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) GO:0001764//neuron migration;GO:0010812//negative regulation of cell-substrate adhesion;GO:0001558//regulation of cell growth;GO:0010951//negative regulation of endopeptidase activity;GO:0021953//central nervous system neuron differentiation;GO:0007165//signal transduction;GO:0010977//negative regulation of neuron projection development GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005509//calcium ion binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0005615//extracellular space;GO:0016528//sarcoplasm;GO:0031594//neuromuscular junction;GO:0033268//node of Ranvier;GO:0005578//proteinaceous extracellular matrix;GO:0014069//postsynaptic density 5 tr|A0A024QZK7|A0A024QZK7_HUMAN Hexokinase 1, isoform CRA_c OS=Homo sapiens GN=HK1 PE=3 SV=1 121818 MGQICQRESATAAEKPKLHLLAESEIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS 102 7.1 5 8 8 6 6 0.894 0.562 0.522 4 4 4 - * * 0.659333333333333 0.204209043221238 tr|A0A024QZK7|A0A024QZK7_HUMAN 100.00 0.0 gi|15991829|ref|NP_277032.1| hexokinase-1 isoform HKI-ta/tb [Homo sapiens] >gi|15991831|ref|NP_277033.1| hexokinase-1 isoform HKI-ta/tb [Homo sapiens] >gi|8996017|gb|AAF82319.1|AAF82319 hexokinase 1 isoform ta/tb [Homo sapiens] >gi|119574706|gb|EAW54321.1| hexokinase 1, isoform CRA_c [Homo sapiens] >gi|119574707|gb|EAW54322.1| hexokinase 1, isoform CRA_c [Homo sapiens] 99.89 0.0 sp|P19367|HXK1_HUMAN Hexokinase-1 OS=Homo sapiens GN=HK1 PE=1 SV=3 100.00 4e-44 F7I8J4 F7I8J4_CALJA Uncharacterized protein (Fragment) OS=Callithrix jacchus PE=3 SV=1 SPAC24H6.04 268 5e-71 COG5026 Hexokinase G Carbohydrate transport and metabolism ; K00844|1|0.0|1892|ptr:450505|hexokinase [EC:2.7.1.1] GO:0055085//transmembrane transport;GO:0015758//glucose transport;GO:0006096//glycolysis;GO:0044281//small molecule metabolic process GO:0004396//hexokinase activity;GO:0005524//ATP binding;GO:0005515//protein binding GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005741//mitochondrial outer membrane;GO:0045121//membrane raft 6 tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN Peroxiredoxin-1 (Fragment) OS=Homo sapiens GN=PRDX1 PE=4 SV=1 23394 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGE 292 36.8 1 35 18 6 4 0.766 0.566 0.591 9 9 9 * * * 0.641 0.108972473588517 tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN 100.00 2e-96 gi|119627382|gb|EAX06977.1| peroxiredoxin 1, isoform CRA_b [Homo sapiens] 100.00 2e-97 sp|Q06830|PRDX1_HUMAN Peroxiredoxin-1 OS=Homo sapiens GN=PRDX1 PE=1 SV=1 100.00 4e-96 H2PYX4 H2PYX4_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000117450 PE=4 SV=1 SPCC576.03c 228 3e-60 COG0450 Peroxiredoxin O Posttranslational modification, protein turnover, chaperones ; K13279|1|2e-97|354|hsa:5052|peroxiredoxin 1 [EC:1.11.1.15] GO:0001501//skeletal system development;GO:0032872//regulation of stress-activated MAPK cascade;GO:0042744//hydrogen peroxide catabolic process;GO:0034101//erythrocyte homeostasis;GO:0042267//natural killer cell mediated cytotoxicity;GO:0008283//cell proliferation;GO:0019430//removal of superoxide radicals;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0055114//oxidation-reduction process GO:0020037//heme binding;GO:0008379//thioredoxin peroxidase activity;GO:0042803//protein homodimerization activity GO:0005759//mitochondrial matrix;GO:0005719//nuclear euchromatin;GO:0042470//melanosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005782//peroxisomal matrix 7 tr|V9HW65|V9HW65_HUMAN Annexin OS=Homo sapiens GN=HEL-S-270 PE=2 SV=1 48819 MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMASRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD 324 25.7 1 22 22 7 7 0.895 0.818 0.614 13 15 13 - * * 0.775666666666667 0.145204453558881 tr|V9HW65|V9HW65_HUMAN 100.00 3e-162 gi|119597993|gb|EAW77587.1| annexin A2, isoform CRA_c [Homo sapiens] 99.71 0.0 sp|Q5R5A0|ANXA2_PONAB Annexin A2 OS=Pongo abelii GN=ANXA2 PE=2 SV=1 100.00 1e-128 H0YMU9 H0YMU9_HUMAN Annexin OS=Homo sapiens GN=ANXA2 PE=3 SV=1 - - - - - - - - GO:0001501//skeletal system development;GO:0001525//angiogenesis;GO:0051099//positive regulation of binding;GO:0007589//body fluid secretion;GO:0031340//positive regulation of vesicle fusion;GO:0042730//fibrinolysis;GO:0030199//collagen fibril organization;GO:0071229//cellular response to acid GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0017137//Rab GTPase binding;GO:0005509//calcium ion binding;GO:0008092//cytoskeletal protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0004859//phospholipase inhibitor activity GO:0005604//basement membrane;GO:0043220//Schmidt-Lanterman incisure;GO:0042470//melanosome;GO:0019897//extrinsic to plasma membrane;GO:0042383//sarcolemma;GO:0043234//protein complex;GO:0005769//early endosome;GO:0030496//midbody;GO:0048471//perinuclear region of cytoplasm;GO:0005811//lipid particle;GO:0035749//myelin sheath adaxonal region 8 tr|F5H0C8|F5H0C8_HUMAN Enolase OS=Homo sapiens GN=ENO2 PE=1 SV=1 41110 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSLELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL 609 16.5 2 34 15 4 2 0.782 0.759 0.732 11 10 11 - * * 0.757666666666667 0.0250266524595946 tr|F5H0C8|F5H0C8_HUMAN 99.04 5e-52 gi|395847555|ref|XP_003796434.1| PREDICTED: gamma-enolase [Otolemur garnettii] 98.60 8e-125 sp|P09104|ENOG_HUMAN Gamma-enolase OS=Homo sapiens GN=ENO2 PE=1 SV=3 100.00 0.0 F5H0C8 F5H0C8_HUMAN Enolase OS=Homo sapiens GN=ENO2 PE=3 SV=1 YGR254w 294 2e-79 COG0148 Enolase G Carbohydrate transport and metabolism ; K01689|1|8e-125|446|hsa:2026|enolase [EC:4.2.1.11] GO:0040010//positive regulation of growth rate;GO:0008340//determination of adult lifespan;GO:0040035//hermaphrodite genitalia development;GO:0014070//response to organic cyclic compound;GO:0002119//nematode larval development;GO:0006096//glycolysis;GO:0006094//gluconeogenesis;GO:0032355//response to estradiol stimulus;GO:0042493//response to drug;GO:0006898//receptor-mediated endocytosis;GO:0044281//small molecule metabolic process;GO:0009792//embryo development ending in birth or egg hatching;GO:0040018//positive regulation of multicellular organism growth GO:0000287//magnesium ion binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0004634//phosphopyruvate hydratase activity GO:0000015//phosphopyruvate hydratase complex;GO:0009986//cell surface;GO:0001917//photoreceptor inner segment;GO:0005886//plasma membrane;GO:0043204//perikaryon 9 sp|Q9NZN4|EHD2_HUMAN EH domain-containing protein 2 OS=Homo sapiens GN=EHD2 PE=1 SV=2 >tr|A0A024R0S6|A0A024R0S6_HUMAN EH-domain containing 2, isoform CRA_a OS=Homo sapiens GN=EHD2 PE=4 SV=1 73158 MFSWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPMVLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDKPFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMGPFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHKGSAE 241 6.8 - 10 10 3 3 0.902 0.762 0.583 10 10 10 - * * 0.749 0.15989684174492 sp|Q9NZN4|EHD2_HUMAN 100.00 0.0 gi|21361462|ref|NP_055416.2| EH domain-containing protein 2 [Homo sapiens] >gi|57015322|sp|Q9NZN4.2|EHD2_HUMAN RecName: Full=EH domain-containing protein 2; AltName: Full=PAST homolog 2 >gi|17981587|gb|AAL51078.1|AF454952_1 EH domain-containing protein-2 [Homo sapiens] >gi|15680192|gb|AAH14445.1| EH-domain containing 2 [Homo sapiens] >gi|119577909|gb|EAW57505.1| EH-domain containing 2, isoform CRA_a [Homo sapiens] >gi|119577910|gb|EAW57506.1| EH-domain containing 2, isoform CRA_a [Homo sapiens] 100.00 0.0 sp|Q9NZN4|EHD2_HUMAN EH domain-containing protein 2 OS=Homo sapiens GN=EHD2 PE=1 SV=2 100.00 0.0 G3S6K4 G3S6K4_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=EHD2 PE=4 SV=1 DR1235 61.6 4e-09 COG0699 Predicted GTPases (dynamin-related) R General function prediction only ; K12469|1|0.0|1076|hsa:30846|EH domain-containing protein 2 GO:0086036//regulation of cardiac muscle cell membrane potential;GO:0072661//protein targeting to plasma membrane;GO:0032456//endocytic recycling;GO:0006184//GTP catabolic process;GO:0007596//blood coagulation;GO:0006897//endocytosis;GO:0051260//protein homooligomerization;GO:0030866//cortical actin cytoskeleton organization GO:0005525//GTP binding;GO:0005509//calcium ion binding;GO:0003676//nucleic acid binding;GO:0019904//protein domain specific binding;GO:0003924//GTPase activity;GO:0005524//ATP binding GO:0055038//recycling endosome membrane;GO:0030139//endocytic vesicle;GO:0005886//plasma membrane;GO:0005634//nucleus 10 sp|P24593|IBP5_HUMAN Insulin-like growth factor-binding protein 5 OS=Homo sapiens GN=IGFBP5 PE=1 SV=1 >tr|A0A024R433|A0A024R433_HUMAN Insulin-like growth factor binding protein 5, isoform CRA_a OS=Homo sapiens GN=IGFBP5 PE=4 SV=1 38269 MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE 225 17.3 - 22 22 4 4 0.431 0.362 0.350 6 7 7 * * * 0.381 0.0437149859887888 sp|P24593|IBP5_HUMAN 100.00 2e-147 gi|10834982|ref|NP_000590.1| insulin-like growth factor-binding protein 5 precursor [Homo sapiens] >gi|124069|sp|P24593.1|IBP5_HUMAN RecName: Full=Insulin-like growth factor-binding protein 5; Short=IBP-5; Short=IGF-binding protein 5; Short=IGFBP-5; Flags: Precursor >gi|184818|gb|AAA53505.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|184820|gb|AAD04730.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|505589|gb|AAA72051.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|3005764|gb|AAC09368.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|15079241|gb|AAH11453.1| Insulin-like growth factor binding protein 5 [Homo sapiens] >gi|42416964|gb|AAS16353.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|54696280|gb|AAV38512.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|54696282|gb|AAV38513.1| insulin-like growth factor binding protein 5 [Homo sapiens] >gi|119590980|gb|EAW70574.1| insulin-like growth factor binding protein 5, isoform CRA_a [Homo sapiens] >gi|119590981|gb|EAW70575.1| insulin-like growth factor binding protein 5, isoform CRA_a [Homo sapiens] 100.00 2e-148 sp|P24593|IBP5_HUMAN Insulin-like growth factor-binding protein 5 OS=Homo sapiens GN=IGFBP5 PE=1 SV=1 99.61 9e-147 F6YKJ0 F6YKJ0_MACMU Uncharacterized protein OS=Macaca mulatta GN=Mmu.4685 PE=4 SV=1 - - - - - - - K10138|1|1e-56|219|mcc:696868|insulin-like growth factor-binding protein 3 GO:0017148//negative regulation of translation;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0001558//regulation of cell growth;GO:0071407//cellular response to organic cyclic compound;GO:0048630//skeletal muscle tissue growth;GO:0051146//striated muscle cell differentiation;GO:0031069//hair follicle morphogenesis;GO:0044342//type B pancreatic cell proliferation;GO:0014912//negative regulation of smooth muscle cell migration;GO:0045668//negative regulation of osteoblast differentiation;GO:0071320//cellular response to cAMP;GO:0060056//mammary gland involution;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway;GO:0010906//regulation of glucose metabolic process;GO:0042593//glucose homeostasis;GO:0051897//positive regulation of protein kinase B signaling cascade GO:0031994//insulin-like growth factor I binding;GO:0001968//fibronectin binding GO:0016942//insulin-like growth factor binding protein complex;GO:0005622//intracellular 11 sp|P35579|MYH9_HUMAN Myosin-9 OS=Homo sapiens GN=MYH9 PE=1 SV=4 >tr|A0A024R1N1|A0A024R1N1_HUMAN Myosin, heavy polypeptide 9, non-muscle, isoform CRA_a OS=Homo sapiens GN=MYH9 PE=4 SV=1 290921 MAQQAADKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAKPAE 2328 18.2 - 101 86 30 24 0.784 0.745 0.714 60 60 59 - * * 0.747666666666667 0.0350761077278157 sp|P35579|MYH9_HUMAN 100.00 0.0 gi|553596|gb|AAA59888.1| cellular myosin heavy chain, partial [Homo sapiens] 100.00 0.0 sp|P35579|MYH9_HUMAN Myosin-9 OS=Homo sapiens GN=MYH9 PE=1 SV=4 100.00 0.0 Q60FE2 Q60FE2_HUMAN MYH9 variant protein OS=Homo sapiens GN=MYH9 PE=2 SV=1 SPCC645.05c 810 0.0 COG5022 Myosin heavy chain Z Cytoskeleton ; K10352|1|0.0|3344|hsa:4627|myosin heavy chain GO:0030220//platelet formation;GO:0032796//uropod organization;GO:0000212//meiotic spindle organization;GO:0030048//actin filament-based movement;GO:0001701//in utero embryonic development;GO:0007411//axon guidance;GO:0051295//establishment of meiotic spindle localization;GO:0031532//actin cytoskeleton reorganization;GO:0016337//cell-cell adhesion;GO:0015031//protein transport;GO:0006200//ATP catabolic process;GO:0006509//membrane protein ectodomain proteolysis;GO:0001768//establishment of T cell polarity;GO:0043534//blood vessel endothelial cell migration;GO:0007520//myoblast fusion;GO:0050900//leukocyte migration;GO:0007132//meiotic metaphase I;GO:0000910//cytokinesis;GO:0030224//monocyte differentiation;GO:0007229//integrin-mediated signaling pathway;GO:0001525//angiogenesis;GO:0008360//regulation of cell shape;GO:0038032//termination of G-protein coupled receptor signaling pathway GO:0042803//protein homodimerization activity;GO:0000146//microfilament motor activity;GO:0030898//actin-dependent ATPase activity;GO:0043495//protein anchor;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0051015//actin filament binding;GO:0043531//ADP binding GO:0005826//actomyosin contractile ring;GO:0001772//immunological synapse;GO:0031594//neuromuscular junction;GO:0005829//cytosol;GO:0016460//myosin II complex;GO:0030863//cortical cytoskeleton;GO:0001931//uropod;GO:0008180//signalosome;GO:0032154//cleavage furrow;GO:0005913//cell-cell adherens junction;GO:0001725//stress fiber;GO:0005819//spindle;GO:0008305//integrin complex;GO:0001726//ruffle 12 tr|A1YYW4|A1YYW4_HUMAN Superoxide dismutase 1 (Fragment) OS=Homo sapiens GN=SOD1 PE=2 SV=1 5330 MATKAVCVLKGDGPVQGIINFEQKESNGPDEGVGKH 604 38.9 2 15 15 1 1 0.837 0.781 0.741 14 15 15 * * * 0.786333333333333 0.0482217101867337 tr|A1YYW4|A1YYW4_HUMAN 100.00 3e-08 gi|34810328|pdb|1P1V|A Chain A, Crystal Structure Of Fals-Associated Human Copper-Zinc Superoxide Dismutase (Cuznsod) Mutant D125h To 1.4a >gi|34810329|pdb|1P1V|B Chain B, Crystal Structure Of Fals-Associated Human Copper-Zinc Superoxide Dismutase (Cuznsod) Mutant D125h To 1.4a >gi|34810330|pdb|1P1V|C Chain C, Crystal Structure Of Fals-Associated Human Copper-Zinc Superoxide Dismutase (Cuznsod) Mutant D125h To 1.4a 100.00 7e-10 sp|P00441|SODC_HUMAN Superoxide dismutase [Cu-Zn] OS=Homo sapiens GN=SOD1 PE=1 SV=2 100.00 3e-08 G3RHP5 G3RHP5_GORGO Superoxide dismutase [Cu-Zn] OS=Gorilla gorilla gorilla GN=SOD1 PE=3 SV=1 - - - - - - - K04565|1|6e-10|62.8|ptr:449637|Cu/Zn superoxide dismutase [EC:1.15.1.1] - - 13 sp|P10599|THIO_HUMAN Thioredoxin OS=Homo sapiens GN=TXN PE=1 SV=3 >tr|H9ZYJ2|H9ZYJ2_HUMAN Thioredoxin OS=Homo sapiens GN=TXN PE=2 SV=1 15970 MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV 637 31.4 - 26 26 3 3 0.791 0.743 0.840 23 24 23 * * * 0.791333333333333 0.0485008590989204 sp|P10599|THIO_HUMAN 100.00 3e-50 gi|441592862|ref|XP_003260517.2| PREDICTED: thioredoxin isoform 1 [Nomascus leucogenys] 100.00 1e-55 sp|P10599|THIO_HUMAN Thioredoxin OS=Homo sapiens GN=TXN PE=1 SV=3 100.00 4e-54 H2QXP0 H2QXP0_PANTR Thioredoxin OS=Pan troglodytes GN=ENSG00000136810 PE=3 SV=1 SPAC7D4.07c 101 3e-22 COG0526 Thiol-disulfide isomerase and thioredoxins OC Posttranslational modification, protein turnover, chaperones ; Energy production and conversion ; K03671|1|4e-58|222|ptr:740248|thioredoxin 1 GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0033158//regulation of protein import into nucleus, translocation;GO:0007267//cell-cell signaling;GO:0006928//cellular component movement;GO:0008283//cell proliferation;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0022900//electron transport chain;GO:0045454//cell redox homeostasis;GO:0015949//nucleobase-containing small molecule interconversion;GO:0006662//glycerol ether metabolic process;GO:0009314//response to radiation;GO:0043388//positive regulation of DNA binding;GO:0045087//innate immune response;GO:0046826//negative regulation of protein export from nucleus GO:0015035//protein disulfide oxidoreductase activity;GO:0005515//protein binding;GO:0009055//electron carrier activity;GO:0015037//peptide disulfide oxidoreductase activity GO:0005654//nucleoplasm;GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005739//mitochondrion 14 tr|G3V1V0|G3V1V0_HUMAN Myosin light polypeptide 6 OS=Homo sapiens GN=MYL6 PE=1 SV=1 21657 MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEGKRRCEGLQESCSHHNPPA 404 28.0 5 25 25 4 4 0.606 0.491 0.544 12 13 13 * * * 0.547 0.0575586657246326 tr|G3V1V0|G3V1V0_HUMAN 100.00 6e-78 gi|431914011|gb|ELK15273.1| Myosin light polypeptide 6 [Pteropus alecto] 100.00 4e-79 sp|Q64119|MYL6_RAT Myosin light polypeptide 6 OS=Rattus norvegicus GN=Myl6 PE=1 SV=3 100.00 1e-77 H2NHN7 H2NHN7_PONAB Myosin light polypeptide 6 OS=Pongo abelii GN=MYL6 PE=4 SV=1 SPAC3A12.14 111 4e-25 COG5126 Ca2+-binding protein (EF-Hand superfamily) TZDR Signal transduction mechanisms ; Cytoskeleton ; Cell cycle control, cell division, chromosome partitioning ; General function prediction only ; K12751|1|2e-79|293|ssc:100625485|myosin light chain 6 GO:0007411//axon guidance;GO:0030049//muscle filament sliding;GO:0007519//skeletal muscle tissue development;GO:0008152//metabolic process GO:0008307//structural constituent of muscle;GO:0000146//microfilament motor activity;GO:0005509//calcium ion binding;GO:0030898//actin-dependent ATPase activity;GO:0005515//protein binding GO:0005829//cytosol;GO:0016461//unconventional myosin complex 15 tr|A0A024R7P5|A0A024R7P5_HUMAN Similar to Laminin receptor 1, isoform CRA_a OS=Homo sapiens GN=LOC388524 PE=3 SV=1 24852 MSGALDVLQIKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFWEPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWGGHA 84 16.1 3 7 7 4 4 0.684 0.536 0.862 4 3 4 * * - 0.694 0.163229899221926 tr|A0A024R7P5|A0A024R7P5_HUMAN 100.00 2e-114 gi|119605356|gb|EAW84950.1| similar to Laminin receptor 1, isoform CRA_a [Homo sapiens] >gi|119605357|gb|EAW84951.1| similar to Laminin receptor 1, isoform CRA_a [Homo sapiens] 98.97 2e-111 sp|P08865|RSSA_HUMAN 40S ribosomal protein SA OS=Homo sapiens GN=RPSA PE=1 SV=4 99.46 9e-104 G1TGI6 G1TGI6_RABIT Uncharacterized protein (Fragment) OS=Oryctolagus cuniculus PE=3 SV=1 SPBC685.06 261 6e-70 COG0052 Ribosomal protein S2 J Translation, ribosomal structure and biogenesis ; K02998|1|2e-111|401|mcc:693293|small subunit ribosomal protein SAe GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006415//translational termination;GO:0006413//translational initiation;GO:0000028//ribosomal small subunit assembly;GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0016337//cell-cell adhesion;GO:0006414//translational elongation;GO:0000461//endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0019083//viral transcription;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006407//rRNA export from nucleus GO:0043236//laminin binding;GO:0043022//ribosome binding;GO:0003735//structural constituent of ribosome GO:0005604//basement membrane;GO:0043025//neuronal cell body;GO:0030686//90S preribosome;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0022627//cytosolic small ribosomal subunit 16 tr|B4DF70|B4DF70_HUMAN cDNA FLJ60461, highly similar to Peroxiredoxin-2 (EC 1.11.1.15) OS=Homo sapiens PE=2 SV=1 23555 MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLAVTRLSPTWMTARNISPNTIRLANG 330 31.1 1 25 17 6 5 0.709 0.567 0.687 7 6 7 - * * 0.654333333333333 0.0764286159323413 tr|B4DF70|B4DF70_HUMAN 100.00 3e-79 gi|90076926|dbj|BAE88143.1| unnamed protein product [Macaca fascicularis] 100.00 1e-87 sp|P32119|PRDX2_HUMAN Peroxiredoxin-2 OS=Homo sapiens GN=PRDX2 PE=1 SV=5 100.00 3e-86 G3S156 G3S156_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=PRDX2 PE=4 SV=1 SPCC576.03c 228 5e-60 COG0450 Peroxiredoxin O Posttranslational modification, protein turnover, chaperones ; K03386|1|1e-87|322|mcc:716665|peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15] GO:0042744//hydrogen peroxide catabolic process;GO:0010310//regulation of hydrogen peroxide metabolic process;GO:0045581//negative regulation of T cell differentiation;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0019430//removal of superoxide radicals;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0048872//homeostasis of number of cells;GO:0048538//thymus development;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0002536//respiratory burst involved in inflammatory response;GO:0055114//oxidation-reduction process;GO:0030194//positive regulation of blood coagulation;GO:0043524//negative regulation of neuron apoptotic process;GO:0000187//activation of MAPK activity;GO:0042098//T cell proliferation GO:0008379//thioredoxin peroxidase activity GO:0005829//cytosol;GO:0005739//mitochondrion 17 tr|F5H5D3|F5H5D3_HUMAN Tubulin alpha-1C chain OS=Homo sapiens GN=TUBA1C PE=1 SV=1 65602 MTAWFNGVEELGRDECFVCLELDPSNGSFLNAKLYISNWILIYFTRTLQLPAPFNTCTSSKSRGEPGCDSKRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAVAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSADGEDEGEEY 708 22.9 3 42 5 9 1 0.337 0.247 0.233 4 5 4 * * * 0.272333333333333 0.0564387573687917 tr|F5H5D3|F5H5D3_HUMAN 100.00 0.0 gi|14389309|ref|NP_116093.1| tubulin alpha-1C chain [Homo sapiens] >gi|20455322|sp|Q9BQE3.1|TBA1C_HUMAN RecName: Full=Tubulin alpha-1C chain; AltName: Full=Alpha-tubulin 6; AltName: Full=Tubulin alpha-6 chain >gi|13436317|gb|AAH04949.1| Tubulin, alpha 1c [Homo sapiens] >gi|13543589|gb|AAH05946.1| Tubulin, alpha 1c [Homo sapiens] >gi|15080013|gb|AAH11790.1| Tubulin, alpha 1c [Homo sapiens] >gi|17939496|gb|AAH19298.1| Tubulin, alpha 1c [Homo sapiens] >gi|18088050|gb|AAH21088.1| Tubulin, alpha 1c [Homo sapiens] >gi|30410987|gb|AAH51297.1| Tubulin, alpha 1c [Homo sapiens] >gi|38648679|gb|AAH63036.1| Tubulin, alpha 1c [Homo sapiens] >gi|119578461|gb|EAW58057.1| tubulin, alpha 6 [Homo sapiens] 100.00 0.0 sp|Q9BQE3|TBA1C_HUMAN Tubulin alpha-1C chain OS=Homo sapiens GN=TUBA1C PE=1 SV=1 100.00 0.0 H2NH68 H2NH68_PONAB Uncharacterized protein OS=Pongo abelii GN=LOC100446260 PE=3 SV=1 SPBC800.05c 723 0.0 COG5023 Tubulin Z Cytoskeleton ; K07374|1|0.0|1021|pon:100446260|tubulin alpha GO:0030705//cytoskeleton-dependent intracellular transport;GO:0051301//cell division;GO:0006184//GTP catabolic process;GO:0051258//protein polymerization;GO:0055085//transmembrane transport;GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement;GO:0051084//'de novo' posttranslational protein folding GO:0005198//structural molecule activity;GO:0005525//GTP binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0003924//GTPase activity;GO:0005524//ATP binding GO:0016021//integral to membrane;GO:0005881//cytoplasmic microtubule 18 tr|V9HW25|V9HW25_HUMAN Epididymis secretory protein Li 273 OS=Homo sapiens GN=HEL-S-273 PE=2 SV=1 43674 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 2086 28.5 - 138 23 9 1 0.334 0.320 0.328 15 16 16 * * * 0.327333333333333 0.0070237691685685 tr|V9HW25|V9HW25_HUMAN 100.00 2e-69 gi|6573280|gb|AAF17621.1| beta tropomyosin [Homo sapiens] 87.32 2e-63 sp|P07951|TPM2_HUMAN Tropomyosin beta chain OS=Homo sapiens GN=TPM2 PE=1 SV=1 100.00 1e-84 F7GT13 F7GT13_MACMU Tropomyosin beta chain isoform 2 OS=Macaca mulatta GN=TPM2 PE=2 SV=1 - - - - - - - K10374|1|6e-86|317|ecb:100055542|tropomyosin 2 GO:0043462//regulation of ATPase activity;GO:0030049//muscle filament sliding GO:0008307//structural constituent of muscle;GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton GO:0005829//cytosol;GO:0005862//muscle thin filament tropomyosin 19 tr|Q5UGI6|Q5UGI6_HUMAN Serine/cysteine proteinase inhibitor clade G member 1 splice variant 2 (Fragment) OS=Homo sapiens GN=SERPING1 PE=2 SV=1 44679 GLQADPADPPAAAAGWGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMLHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDPRA 196 6.3 3 16 16 2 2 0.564 0.310 0.679 9 9 5 * * - 0.517666666666667 0.188812958594831 tr|Q5UGI6|Q5UGI6_HUMAN 100.00 1e-59 gi|14192835|dbj|BAB55877.1| complement C1 inhibitor [Pan troglodytes] >gi|14192837|dbj|BAB55878.1| complement C1 inhibitor [Pan troglodytes] 99.68 1e-177 sp|P05155|IC1_HUMAN Plasma protease C1 inhibitor OS=Homo sapiens GN=SERPING1 PE=1 SV=2 100.00 5e-59 Q95J66 Q95J66_PANTR Complement C1 inhibitor (Fragment) OS=Pan troglodytes GN=SERPING1 PE=4 SV=1 all0778 103 6e-22 COG4826 Serine protease inhibitor O Posttranslational modification, protein turnover, chaperones ; K04001|1|2e-177|622|hsa:710|C1 inhibitor GO:0030168//platelet activation;GO:0001869//negative regulation of complement activation, lectin pathway;GO:0010951//negative regulation of endopeptidase activity;GO:0008015//blood circulation;GO:0042730//fibrinolysis;GO:0007597//blood coagulation, intrinsic pathway;GO:0006958//complement activation, classical pathway;GO:0002576//platelet degranulation;GO:0006508//proteolysis GO:0005515//protein binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008233//peptidase activity GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space 20 sp|P07237|PDIA1_HUMAN Protein disulfide-isomerase OS=Homo sapiens GN=P4HB PE=1 SV=3 >tr|A0A024R8S5|A0A024R8S5_HUMAN Protein disulfide-isomerase OS=Homo sapiens GN=P4HB PE=3 SV=1 72082 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL 1009 32.1 - 86 86 15 15 0.749 0.541 0.775 52 52 52 - * * 0.688333333333333 0.128254954420222 sp|P07237|PDIA1_HUMAN 100.00 0.0 gi|426346301|ref|XP_004040818.1| PREDICTED: protein disulfide-isomerase [Gorilla gorilla gorilla] 100.00 0.0 sp|P07237|PDIA1_HUMAN Protein disulfide-isomerase OS=Homo sapiens GN=P4HB PE=1 SV=3 100.00 8e-87 B3KTQ9 B3KTQ9_HUMAN Procollagen-proline, 2-oxoglutarate 4-dioxygenase (Proline 4-hydroxylase), beta polypeptide, isoform CRA_b OS=Homo sapiens GN=P4HB PE=2 SV=1 SPAC1F5.02 272 1e-72 COG0526 Thiol-disulfide isomerase and thioredoxins OC Posttranslational modification, protein turnover, chaperones ; Energy production and conversion ; K09580|1|0.0|945|hsa:5034|protein disulfide-isomerase A1 [EC:5.3.4.1] GO:0006662//glycerol ether metabolic process;GO:0006629//lipid metabolic process;GO:0045454//cell redox homeostasis;GO:0042157//lipoprotein metabolic process;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0030198//extracellular matrix organization GO:0003756//protein disulfide isomerase activity;GO:0004656//procollagen-proline 4-dioxygenase activity;GO:0009055//electron carrier activity;GO:0046982//protein heterodimerization activity;GO:0015035//protein disulfide oxidoreductase activity GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0009986//cell surface;GO:0042470//melanosome;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005886//plasma membrane 21 tr|W6I206|W6I206_HUMAN Lysyl oxidase-like 2 delta e13 OS=Homo sapiens GN=LOXL2 PE=2 SV=1 94700 MERPLCSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETAPDLVLNAEMVQQTTYLEDRPMFLLQCAMEENCLSASAAQTDPTTGYRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLNGTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVPPGDYLFQVVPSAKRRKKSLSTSAGS 303 11.1 2 12 12 5 5 0.470 0.357 0.327 10 9 9 * * * 0.384666666666667 0.0754077803236067 tr|W6I206|W6I206_HUMAN 100.00 0.0 gi|12653633|gb|AAH00594.1| Lysyl oxidase-like 2 [Homo sapiens] >gi|119584029|gb|EAW63625.1| lysyl oxidase-like 2, isoform CRA_a [Homo sapiens] 99.86 0.0 sp|Q9Y4K0|LOXL2_HUMAN Lysyl oxidase homolog 2 OS=Homo sapiens GN=LOXL2 PE=1 SV=1 100.00 5e-70 E5RJL2 E5RJL2_HUMAN Lysyl oxidase homolog 2 (Fragment) OS=Homo sapiens GN=LOXL2 PE=4 SV=1 - - - - - - - K00280|1|0.0|1447|hsa:4017|lysyl oxidase-like protein 2/3/4 [EC:1.4.3.-] GO:0043542//endothelial cell migration;GO:0032332//positive regulation of chondrocyte differentiation;GO:0007155//cell adhesion;GO:0001837//epithelial to mesenchymal transition;GO:0016570//histone modification;GO:0001935//endothelial cell proliferation;GO:0007568//aging;GO:0002040//sprouting angiogenesis;GO:0018277//protein deamination;GO:0045892//negative regulation of transcription, DNA-dependent;GO:0001666//response to hypoxia;GO:0030199//collagen fibril organization;GO:0055114//oxidation-reduction process GO:0003714//transcription corepressor activity;GO:0004720//protein-lysine 6-oxidase activity;GO:0009055//electron carrier activity;GO:0005044//scavenger receptor activity;GO:0003682//chromatin binding;GO:0005507//copper ion binding;GO:0035064//methylated histone residue binding GO:0005604//basement membrane;GO:0016020//membrane;GO:0005615//extracellular space;GO:0005694//chromosome;GO:0005634//nucleus 22 sp|Q99584|S10AD_HUMAN Protein S100-A13 OS=Homo sapiens GN=S100A13 PE=1 SV=1 15723 MAAEPLTELEESIETVVTTFFTFARQEGRKDSLSVNEFKELVTQQLPHLLKDVGSLDEKMKSLDVNQDSELKFNEYWRLIGELAKEIRKKKDLKIRKK 248 32.7 - 14 14 3 3 0.943 0.764 0.663 11 11 11 - * * 0.79 0.141799153735133 sp|Q99584|S10AD_HUMAN 100.00 3e-21 gi|119573681|gb|EAW53296.1| S100 calcium binding protein A13, isoform CRA_a [Homo sapiens] >gi|119573682|gb|EAW53297.1| S100 calcium binding protein A13, isoform CRA_a [Homo sapiens] >gi|119573685|gb|EAW53300.1| S100 calcium binding protein A13, isoform CRA_a [Homo sapiens] 100.00 1e-42 sp|Q99584|S10AD_HUMAN Protein S100-A13 OS=Homo sapiens GN=S100A13 PE=1 SV=1 100.00 1e-20 D3DV53 D3DV53_HUMAN S100 calcium binding protein A13, isoform CRA_a (Fragment) OS=Homo sapiens GN=S100A13 PE=4 SV=1 - - - - - - - K10384|1|1e-06|51.2|aml:100480898|filaggrin!K14734|3|3e-06|50.4|ecb:100033995|S100 calcium binding protein G GO:0043303//mast cell degranulation;GO:0008360//regulation of cell shape;GO:0050703//interleukin-1 alpha secretion;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB cascade;GO:0051602//response to electrical stimulus;GO:0046688//response to copper ion;GO:0008284//positive regulation of cell proliferation GO:0050786//RAGE receptor binding;GO:0008144//drug binding;GO:0005507//copper ion binding;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0008289//lipid binding;GO:0017134//fibroblast growth factor binding;GO:0042803//protein homodimerization activity GO:0005829//cytosol;GO:0005615//extracellular space;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus 23 tr|A4QPB0|A4QPB0_HUMAN IQ motif containing GTPase activating protein 1 OS=Homo sapiens GN=IQGAP1 PE=2 SV=1 230857 MSAADEVDGLGVARPHYGSVLDNERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFKLGLAPQIQDLYGKVDFTEEEINNMKTELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIDRRIPADTFAALKNPNAMLVNLEEPLASTYQDILYQAKQDKMTNAKNRTENSERERDVYEELLTQAEIQGNINKVNTFSALANIDLALEQGDALALFRALQSPALGLRGLQQQNSDWYLKQLLSDKQQKRQSGQTDPLQKEELQSGVDAANSAAQQYQRRLAAVALINAAIQKGVAEKTVLELMNPEAQLPQVYPFAADLYQKELVTLQRQSPEHNLTHPELSVAVEMLSSVALINRALESGDVNTVWKQLSSSVTGLTNIEEENCQRYLDELMKLKAQAHAENNEFITWNDIQACVDHVNLVVQEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGVLAEVAQHYQDTLIRAKREKAQEIQDESAVLWLDEIQGGIWQSNKDTQEAQKFALGIFAINEAVESGDVGKTLSALRSPDVGLYGVIPECGETYHSDLAEAKKKKLAVGDNNSKWVKHWVKGGYYYYHNLETQEGGWDEPPNFVQNSMQLSREEIQSSISGVTAAYNREQLWLANEGLITRLQARCRGYLVRQEFRSRMNFLKKQIPAITCIQSQWRGYKQKKAYQDRLAYLRSHKDEVVKIQSLARMHQARKRYRDRLQYFRDHINDIIKIQAFIRANKARDDYKTLINAEDPPMVVVRKFVHLLDQSDQDFQEELDLMKMREEVITLIRSNQQLENDLNLMDIKIGLLVKNKITLQDVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFKTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALAHEEVKTRLDSSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFFQTACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESSGNLNDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRRAIRDAKTPDKMKKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKATFYGEQVDYYKSYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKFMGVQMETFMLHYQDLLQLQYEGVAVMKLFDRAKVNVNLLIFLLNKKFYGK 1066 17.6 1 50 50 26 26 0.778 0.619 0.558 33 35 30 * - * 0.651666666666667 0.113579634324703 tr|A4QPB0|A4QPB0_HUMAN 100.00 1e-112 gi|301015769|pdb|3I6X|A Chain A, Crystal Structure Of The Calponin Homology Domain Of Iqgap1 >gi|301015770|pdb|3I6X|B Chain B, Crystal Structure Of The Calponin Homology Domain Of Iqgap1 >gi|301015771|pdb|3I6X|C Chain C, Crystal Structure Of The Calponin Homology Domain Of Iqgap1 >gi|301015772|pdb|3I6X|D Chain D, Crystal Structure Of The Calponin Homology Domain Of Iqgap1 99.94 0.0 sp|P46940|IQGA1_HUMAN Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens GN=IQGAP1 PE=1 SV=1 100.00 5e-10 B4E2M0 B4E2M0_HUMAN cDNA FLJ55443, highly similar to Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens PE=2 SV=1 SPAC4F8.13c 385 2e-106 COG5261 Protein involved in regulation of cellular morphogenesis/cytokinesis DT Cell cycle control, cell division, chromosome partitioning ; Signal transduction mechanisms ; K05767|1|0.0|3365|hsa:8826|IQ motif containing GTPase activating protein GO:0071277//cellular response to calcium ion;GO:0072015//glomerular visceral epithelial cell development;GO:0006112//energy reserve metabolic process;GO:0050796//regulation of insulin secretion;GO:0001817//regulation of cytokine production;GO:0035305//negative regulation of dephosphorylation;GO:0007264//small GTPase mediated signal transduction;GO:0045860//positive regulation of protein kinase activity;GO:0043547//positive regulation of GTPase activity GO:0005095//GTPase inhibitor activity;GO:0019901//protein kinase binding;GO:0005509//calcium ion binding;GO:0019903//protein phosphatase binding;GO:0048365//Rac GTPase binding;GO:0005099//Ras GTPase activator activity;GO:0005516//calmodulin binding GO:0043005//neuron projection;GO:0005884//actin filament;GO:0036057//slit diaphragm;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005874//microtubule;GO:0031252//cell leading edge;GO:0016328//lateral plasma membrane;GO:0030496//midbody;GO:0030529//ribonucleoprotein complex 24 sp|P67936|TPM4_HUMAN Tropomyosin alpha-4 chain OS=Homo sapiens GN=TPM4 PE=1 SV=3 >tr|V9HW56|V9HW56_HUMAN Epididymis secretory protein Li 108 OS=Homo sapiens GN=HEL-S-108 PE=2 SV=1 36528 MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 1873 18.5 - 113 6 6 1 0.544 0.494 0.660 6 6 6 * * * 0.566 0.0851586754241751 sp|P67936|TPM4_HUMAN 100.00 1e-59 gi|334326964|ref|XP_003340817.1| PREDICTED: tropomyosin alpha-4 chain-like isoform 1 [Monodelphis domestica] >gi|395513661|ref|XP_003761041.1| PREDICTED: tropomyosin alpha-1 chain isoform 1 [Sarcophilus harrisii] 100.00 1e-75 sp|P67936|TPM4_HUMAN Tropomyosin alpha-4 chain OS=Homo sapiens GN=TPM4 PE=1 SV=3 100.00 4e-74 E2R662 E2R662_CANFA Uncharacterized protein OS=Canis familiaris GN=TPM4 PE=3 SV=1 - - - - - - - K10375|1|2e-75|282|ptr:100612873|tropomyosin 4 GO:0006979//response to oxidative stress;GO:0030049//muscle filament sliding;GO:0055003//cardiac myofibril assembly;GO:0060048//cardiac muscle contraction GO:0008307//structural constituent of muscle;GO:0046872//metal ion binding GO:0005829//cytosol;GO:0030863//cortical cytoskeleton;GO:0002102//podosome;GO:0001725//stress fiber;GO:0005862//muscle thin filament tropomyosin;GO:0031941//filamentous actin 25 tr|Q0QEN7|Q0QEN7_HUMAN ATP synthase subunit beta (Fragment) OS=Homo sapiens GN=ATP5B PE=2 SV=1 54471 AVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFMEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHMGKLVPLKETIKGFQQILAGEYDHLPEQAFYM 97 8.1 1 5 5 3 3 0.840 0.513 0.569 4 3 4 - * * 0.640666666666667 0.174883770926102 tr|Q0QEN7|Q0QEN7_HUMAN 100.00 0.0 gi|114644226|ref|XP_509149.2| PREDICTED: ATP synthase subunit beta, mitochondrial isoform 2 [Pan troglodytes] 100.00 0.0 sp|P06576|ATPB_HUMAN ATP synthase subunit beta, mitochondrial OS=Homo sapiens GN=ATP5B PE=1 SV=3 100.00 0.0 Q0QEN7 Q0QEN7_HUMAN ATP synthase subunit beta (Fragment) OS=Homo sapiens GN=ATP5B PE=2 SV=1 BMEI0251 728 0.0 COG0055 F0F1-type ATP synthase, beta subunit C Energy production and conversion ; K02133|1|0.0|862|hsa:506|F-type H+-transporting ATPase subunit beta [EC:3.6.3.14] GO:0001525//angiogenesis;GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0006898//receptor-mediated endocytosis;GO:0006172//ADP biosynthetic process;GO:0051453//regulation of intracellular pH;GO:0015991//ATP hydrolysis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0042777//plasma membrane ATP synthesis coupled proton transport;GO:0006629//lipid metabolic process;GO:0006200//ATP catabolic process;GO:0022904//respiratory electron transport chain GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0030228//lipoprotein particle receptor activity;GO:0005509//calcium ion binding;GO:0042288//MHC class I protein binding;GO:0043499//eukaryotic cell surface binding;GO:0005524//ATP binding GO:0042645//mitochondrial nucleoid;GO:0009986//cell surface;GO:0005754//mitochondrial proton-transporting ATP synthase, catalytic core;GO:0005886//plasma membrane 26 tr|A3KC71|A3KC71_HUMAN Nuclear envelope protein okuribin OS=Homo sapiens GN=okuribin PE=2 SV=1 133464 MTWRMGPRFTMLLAMWLVCGSEPHPHATIRGSHGGRKVPLVSPDSSRPARFLRHTGRSRGIERSTLEEPNLQPLQRRRSVPVLRLARPTEPPARSDINGAAVRPEQRPAARGSPREMIRDEGSSARSRMLRFPSGSSSPNILASFAGKNRVWVISAPHASEGYYRLMMSLLKDDVYCELAERHIQQIVLFHQAGEEGGKVRRITSEGQILEQPLDPSLIPKLMSFLKLEKGKFGMVLLKKTLQVEERYPYPVRLEAMYEVIDQGPIRRIEKIRQKGFVQKCKASGVEGQVVAEGNDGGGGAGRPSLGSEKKKEDPRRAQVPPTRESRVKVLRKLAATAPALPQPPSTPRATTLPPAPATTVTRSTSRAVTVAARPMTTTAFPTTQRPWTPSPSHRPPTTTEVITARRPSVSENLYPPSRKDQHRERPQTTRRPSKATSLESFTNAPPTTISEPSTRAAGXGRFRDNRMDRREHGHRDPNVVPGPPKPAKEKPPKKKAQDKILSNEYEEKYDLSRPTASQLEDELQVGNVPLKKAKESKKHEKLEKPEKEKKKKMKNENADKLLKSEKQMKKSEKKSKQEKEKSKKKKGGKTEQDGYQKPTNKHFTQSPKKSVADLLGSFEGKRRLLLITAPKAENNMYVQQRDEYLESFCKMATRKISVITIFGPVNNSTMKIDHFQLDNEKPMRVVDDEDLVDQRLISELRKEYGMTYNDFFMVLTDVDLRVKQYYEVPITMKSVFDLIDTFQSRIKDMEKQKKEGIVCKEDKKQSLENFLSRFRWRRRLLVISAPNDEDWAYSQQLSALSGQACNFGLRHITILKLLGVGEEVGGVLELFPINGSSVVEREDVPAHLVKDIRNYFQVSPEYFSMLLVGKDGNVKSWYPSPMWSMVIVYDLIDSMQLRRQEMAIQQSLGMRCPEDEYAGYGYHSYHQGYQDGYQDDYRHHESYHHGYPY 566 15.8 2 42 42 14 14 0.522 0.240 0.310 25 26 27 * * * 0.357333333333333 0.146837778971671 tr|A3KC71|A3KC71_HUMAN 100.00 5e-27 gi|27469607|gb|AAH42105.1| CCDC80 protein [Homo sapiens] 99.89 0.0 sp|Q76M96|CCD80_HUMAN Coiled-coil domain-containing protein 80 OS=Homo sapiens GN=CCDC80 PE=1 SV=1 100.00 2e-26 F7GYI8 F7GYI8_CALJA Uncharacterized protein OS=Callithrix jacchus GN=CCDC80 PE=4 SV=1 - - - - - - - - - - GO:0005578//proteinaceous extracellular matrix 27 sp|Q9Y281|COF2_HUMAN Cofilin-2 OS=Homo sapiens GN=CFL2 PE=1 SV=1 >tr|Q549N0|Q549N0_HUMAN Cofilin 2 (Muscle), isoform CRA_a OS=Homo sapiens GN=CFL2 PE=2 SV=1 26140 MASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL 563 31.9 - 29 10 5 2 0.639 0.750 0.671 8 8 8 * * * 0.686666666666667 0.0571343446040412 sp|Q9Y281|COF2_HUMAN 100.00 3e-91 gi|338717974|ref|XP_001490861.2| PREDICTED: cofilin-2-like [Equus caballus] 100.00 2e-92 sp|Q9Y281|COF2_HUMAN Cofilin-2 OS=Homo sapiens GN=CFL2 PE=1 SV=1 100.00 1e-23 Q5MAR8 Q5MAR8_CANFA Cofilin 2 (Fragment) OS=Canis familiaris PE=4 SV=1 - - - - - - - K05765|1|2e-93|340|ptr:452853|cofilin - GO:0003779//actin binding GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0016363//nuclear matrix 28 sp|P07996|TSP1_HUMAN Thrombospondin-1 OS=Homo sapiens GN=THBS1 PE=1 SV=2 150327 MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAGGRLGLFVFSQEMVFFSDLKYECRDP 2018 26.1 - 143 5 27 1 0.294 0.334 0.189 4 4 3 * * * 0.272333333333333 0.0748888064622032 sp|P07996|TSP1_HUMAN 100.00 0.0 gi|118600432|gb|AAH28145.1| THBS1 protein [Homo sapiens] 100.00 0.0 sp|P07996|TSP1_HUMAN Thrombospondin-1 OS=Homo sapiens GN=THBS1 PE=1 SV=2 100.00 0.0 A0PJG0 A0PJG0_HUMAN THBS1 protein (Fragment) OS=Homo sapiens GN=THBS1 PE=2 SV=1 - - - - - - - K04659|1|0.0|2225|ptr:453319|thrombospondin GO:0016525//negative regulation of angiogenesis;GO:2000462//positive regulation of eukaryotic cell surface binding;GO:0006955//immune response;GO:0043032//positive regulation of macrophage activation;GO:0043652//engulfment of apoptotic cell;GO:0003417//growth plate cartilage development;GO:0045727//positive regulation of translation;GO:0009749//response to glucose stimulus;GO:0002581//negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0045766//positive regulation of angiogenesis;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0032695//negative regulation of interleukin-12 production;GO:0018149//peptide cross-linking;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0010763//positive regulation of fibroblast migration;GO:0051895//negative regulation of focal adhesion assembly;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0030168//platelet activation;GO:0051918//negative regulation of fibrinolysis;GO:0010757//negative regulation of plasminogen activation;GO:0001666//response to hypoxia;GO:0034605//cellular response to heat;GO:0051592//response to calcium ion;GO:0010811//positive regulation of cell-substrate adhesion;GO:0010748//negative regulation of plasma membrane long-chain fatty acid transport;GO:0001937//negative regulation of endothelial cell proliferation;GO:0032026//response to magnesium ion;GO:0002576//platelet degranulation;GO:0010754//negative regulation of cGMP-mediated signaling;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0032570//response to progesterone stimulus;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0002544//chronic inflammatory response;GO:0007050//cell cycle arrest;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0002605//negative regulation of dendritic cell antigen processing and presentation;GO:0051897//positive regulation of protein kinase B signaling cascade;GO:0000187//activation of MAPK activity;GO:0042493//response to drug;GO:0002040//sprouting angiogenesis;GO:0010759//positive regulation of macrophage chemotaxis;GO:0006917//induction of apoptosis GO:0070051//fibrinogen binding;GO:0008201//heparin binding;GO:0070052//collagen V binding;GO:0005178//integrin binding;GO:0017134//fibroblast growth factor binding;GO:0001968//fibronectin binding;GO:0042802//identical protein binding;GO:0030169//low-density lipoprotein particle binding;GO:0001786//phosphatidylserine binding;GO:0043499//eukaryotic cell surface binding;GO:0050431//transforming growth factor beta binding;GO:0005509//calcium ion binding;GO:0043394//proteoglycan binding;GO:0043236//laminin binding GO:0005577//fibrinogen complex;GO:0009897//external side of plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0031012//extracellular matrix 29 sp|Q14204|DYHC1_HUMAN Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens GN=DYNC1H1 PE=1 SV=5 624245 MSEPGGGGGEDGSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGEAPAALEAALEEKSALEQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIKRTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGVTGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLCTE 213 4.4 - 21 21 19 19 0.965 0.692 0.566 7 8 8 - * * 0.741 0.203963231980669 sp|Q14204|DYHC1_HUMAN 100.00 0.0 gi|71891782|dbj|BAA20783.3| KIAA0325 protein [Homo sapiens] 100.00 0.0 sp|Q14204|DYHC1_HUMAN Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens GN=DYNC1H1 PE=1 SV=5 100.00 2e-127 G3QD10 G3QD10_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=DYNC1H1 PE=4 SV=1 YKR054c 1861 0.0 COG5245 Dynein, heavy chain Z Cytoskeleton ; K10413|1|0.0|9458|hsa:1778|dynein heavy chain 1, cytosolic GO:0006810//transport;GO:0007052//mitotic spindle organization;GO:0034063//stress granule assembly;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0008219//cell death;GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement;GO:0000086//G2/M transition of mitotic cell cycle;GO:0033962//cytoplasmic mRNA processing body assembly GO:0005515//protein binding;GO:0003777//microtubule motor activity;GO:0042623//ATPase activity, coupled;GO:0005524//ATP binding GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0005874//microtubule;GO:0005813//centrosome;GO:0005868//cytoplasmic dynein complex 30 tr|B4DY28|B4DY28_HUMAN cDNA FLJ61189, highly similar to Cysteine and glycine-rich protein 1 OS=Homo sapiens PE=2 SV=1 27880 MPNWGGGKKCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYCKSCYGKKYGPKGYGYGQGAGTLSTDKGESLGIKHEEAPGHRPTTNPNASKFAQKIGGSERCPRCSQAVYAAEKSWHKACFRCAKCGKGLESTTLADKDGEIYCKGCYAKNFGPKGFGFGQGAGALVHSE 805 42.8 2 28 28 6 6 0.551 0.605 0.482 25 26 25 * - * 0.546 0.0616522505671934 tr|B4DY28|B4DY28_HUMAN 100.00 3e-56 gi|62089098|dbj|BAD92993.1| cysteine and glycine-rich protein 1 variant [Homo sapiens] 96.89 8e-78 sp|P21291|CSRP1_HUMAN Cysteine and glycine-rich protein 1 OS=Homo sapiens GN=CSRP1 PE=1 SV=3 100.00 1e-55 Q59EQ5 Q59EQ5_HUMAN Cysteine and glycine-rich protein 1 variant (Fragment) OS=Homo sapiens PE=2 SV=1 - - - - - - - K09377|1|4e-81|300|ptr:457621|cysteine and glycine-rich protein GO:0007399//nervous system development;GO:0030036//actin cytoskeleton organization GO:0046872//metal ion binding;GO:0005515//protein binding GO:0015629//actin cytoskeleton 31 sp|P09382|LEG1_HUMAN Galectin-1 OS=Homo sapiens GN=LGALS1 PE=1 SV=2 17786 MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD 1515 43.7 - 81 81 5 5 0.764 0.667 0.675 43 45 42 * * * 0.702 0.0538423625038872 sp|P09382|LEG1_HUMAN 100.00 3e-74 gi|4504981|ref|NP_002296.1| galectin-1 [Homo sapiens] >gi|184228|gb|AAB00777.1| 14 kDa beta-galactoside-binding lectin [Homo sapiens] >gi|307122|gb|AAA36170.1| lectin precursor [Homo sapiens] >gi|4377694|emb|CAA33328.1| 14 kDa beta-galactoside-binding lectin [Homo sapiens] >gi|12804557|gb|AAH01693.1| Lectin, galactoside-binding, soluble, 1 [Homo sapiens] >gi|18088370|gb|AAH20675.1| Lectin, galactoside-binding, soluble, 1 [Homo sapiens] >gi|30582389|gb|AAP35421.1| lectin, galactoside-binding, soluble, 1 (galectin 1) [Homo sapiens] >gi|47678553|emb|CAG30397.1| LGALS1 [Homo sapiens] >gi|119580582|gb|EAW60178.1| lectin, galactoside-binding, soluble, 1 (galectin 1) [Homo sapiens] >gi|169635015|gb|ACA58297.1| beta-galactoside-binding lectin precursor [Homo sapiens] 100.00 3e-75 sp|P09382|LEG1_HUMAN Galectin-1 OS=Homo sapiens GN=LGALS1 PE=1 SV=2 100.00 1e-73 H2QLM5 H2QLM5_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000100097 PE=4 SV=1 - - - - - - - K06830|1|3e-75|279|hsa:3956|galectin-1 GO:0071333//cellular response to glucose stimulus;GO:0042981//regulation of apoptotic process;GO:0033555//multicellular organismal response to stress;GO:0071407//cellular response to organic cyclic compound;GO:0045445//myoblast differentiation;GO:0034120//positive regulation of erythrocyte aggregation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB cascade;GO:0010812//negative regulation of cell-substrate adhesion;GO:0048678//response to axon injury;GO:0042493//response to drug;GO:0010977//negative regulation of neuron projection development GO:0004871//signal transducer activity;GO:0043236//laminin binding;GO:0016936//galactoside binding;GO:0001948//glycoprotein binding;GO:0030395//lactose binding;GO:0042803//protein homodimerization activity GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0005578//proteinaceous extracellular matrix;GO:0005634//nucleus 32 tr|E9PKE3|E9PKE3_HUMAN Heat shock cognate 71 kDa protein OS=Homo sapiens GN=HSPA8 PE=1 SV=1 85723 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 1047 29.7 1 50 34 14 12 0.814 0.690 0.680 22 25 24 * * * 0.728 0.0746458304260861 tr|E9PKE3|E9PKE3_HUMAN 99.83 0.0 gi|63101351|gb|AAH94900.1| Hspa8 protein [Mus musculus] 96.90 0.0 sp|P11142|HSP7C_HUMAN Heat shock cognate 71 kDa protein OS=Homo sapiens GN=HSPA8 PE=1 SV=1 100.00 0.0 E9PKE3 E9PKE3_HUMAN Heat shock cognate 71 kDa protein OS=Homo sapiens GN=HSPA8 PE=3 SV=1 SPAC13G7.02c 933 0.0 COG0443 Molecular chaperone O Posttranslational modification, protein turnover, chaperones ; K03283|1|0.0|1125|ecb:100009679|heat shock 70kDa protein 1/8 GO:0016044//cellular membrane organization;GO:0007269//neurotransmitter secretion;GO:0006397//mRNA processing;GO:0045892//negative regulation of transcription, DNA-dependent;GO:0008380//RNA splicing;GO:0051726//regulation of cell cycle;GO:0019048//virus-host interaction;GO:0051085//chaperone mediated protein folding requiring cofactor;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006200//ATP catabolic process;GO:0006986//response to unfolded protein GO:0005102//receptor binding;GO:0043531//ADP binding;GO:0051082//unfolded protein binding;GO:0042623//ATPase activity, coupled;GO:0005524//ATP binding GO:0043005//neuron projection;GO:0042470//melanosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005681//spliceosomal complex;GO:0009986//cell surface;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0043025//neuronal cell body;GO:0070062//extracellular vesicular exosome;GO:0000974//Prp19 complex;GO:0008021//synaptic vesicle;GO:0005886//plasma membrane 33 sp|P63104|1433Z_HUMAN 14-3-3 protein zeta/delta OS=Homo sapiens GN=YWHAZ PE=1 SV=1 >tr|D0PNI1|D0PNI1_HUMAN Epididymis luminal protein 4 OS=Homo sapiens GN=YWHAZ PE=2 SV=1 34287 MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGEN 959 33.1 - 52 34 8 6 0.979 0.766 0.723 24 24 24 - * * 0.822666666666667 0.137085131700463 sp|P63104|1433Z_HUMAN 100.00 2e-133 gi|338728575|ref|XP_003365700.1| PREDICTED: 14-3-3 protein zeta/delta-like isoform 3 [Equus caballus] 100.00 2e-134 sp|Q5R651|1433Z_PONAB 14-3-3 protein zeta/delta OS=Pongo abelii GN=YWHAZ PE=2 SV=1 100.00 6e-133 F6XEB4 F6XEB4_HORSE Uncharacterized protein OS=Equus caballus GN=LOC100056060 PE=3 SV=1 SPAC8E11.02c 328 4e-90 COG5040 14-3-3 family protein T Signal transduction mechanisms ; K06630|1|3e-136|484|aml:100484483|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein GO:0030168//platelet activation;GO:0010467//gene expression;GO:0007165//signal transduction;GO:0042493//response to drug;GO:0002553//histamine secretion by mast cell;GO:0016071//mRNA metabolic process;GO:0006626//protein targeting to mitochondrion GO:0016301//kinase activity;GO:0019904//protein domain specific binding;GO:0032403//protein complex binding;GO:0008134//transcription factor binding GO:0005654//nucleoplasm;GO:0042470//melanosome;GO:0005829//cytosol;GO:0031252//cell leading edge;GO:0043234//protein complex;GO:0014069//postsynaptic density;GO:0048471//perinuclear region of cytoplasm;GO:0005739//mitochondrion 34 sp|O75326|SEM7A_HUMAN Semaphorin-7A OS=Homo sapiens GN=SEMA7A PE=1 SV=1 84073 MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHLRSGPRIFAVWKGHVGQDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRTVNIGSTKGSCLDKRDCENYITLLERRSEGLLACGTNARHPSCWNLVNGTVVPLGEMRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKVFRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSERSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHACALAASLWLGVLPTLTLGLLVH 153 5.6 - 11 11 3 3 0.696 0.701 0.714 6 5 5 - * * 0.703666666666667 0.00929157324317758 sp|O75326|SEM7A_HUMAN 100.00 0.0 gi|3551779|gb|AAC34741.1| semaphorin L [Homo sapiens] 100.00 0.0 sp|O75326|SEM7A_HUMAN Semaphorin-7A OS=Homo sapiens GN=SEMA7A PE=1 SV=1 100.00 0.0 F5GYX3 F5GYX3_HUMAN Semaphorin-7A OS=Homo sapiens GN=SEMA7A PE=4 SV=1 - - - - - - - K06529|1|0.0|1274|pon:100451776|semaphorin 7 GO:0007411//axon guidance;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0060907//positive regulation of macrophage cytokine production;GO:0007229//integrin-mediated signaling pathway;GO:0045773//positive regulation of axon extension;GO:0050727//regulation of inflammatory response GO:0005178//integrin binding;GO:0004872//receptor activity GO:0031225//anchored to membrane;GO:0009897//external side of plasma membrane 35 sp|Q9Y490|TLN1_HUMAN Talin-1 OS=Homo sapiens GN=TLN1 PE=1 SV=3 321351 MVALSLKISIGNVVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKKGIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELMEEKKEEITGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQKGERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEHGSVALPAIMRSGASGPENFQVGSMPPAQQQITSGQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFDTLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLEDEGGSGRPLLQAAKGLAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQIGESDTDPHFQDALMQLAKAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGESDLENSRKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASTPKASAGPQPLLVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASAMQLSQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSVVQNLEKDLQEVKAAARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLRSLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVAKAVTQALNRCVSCLPGQRDVDNALRAVGDASKRLLSDSLPPSTGTFQEAQSRLNEAAAGLNQAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLLAAKALSTDPAAPNLKSQLAAAARAVTDSINQLITMCTQQAPGQKECDNALRELETVRELLENPVQPINDMSYFGCLDSVMENSKVLGEAMTGISQNAKNGNLPEFGDAISTASKALCGFTEAAAQAAYLVGVSDPNSQAGQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQVLSAATIVAKHTSALCNSCRLASARTTNPTAKRQFVQSAKEVANSTANLVKTIKALDGAFTEENRAQCRAATAPLLEAVDNLSAFASNPEFSSIPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPSWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLANAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGEPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASEAKPAAVAAENEEIGSHIKHRVQELGHGCAALVTKAGALQCSPSDAYTKKELIECARRVSEKVSHVLAALQAGNRGTQACITAASAVSGIIADLDTTIMFATAGTLNREGTETFADHREGILKTAKVLVEDTKVLVQNAAGSQEKLAQAAQSSVATITRLADVVKLGAASLGAEDPETQVVLINAVKDVAKALGDLISATKAAAGKVGDDPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATTEHIRQELAVFCSPEPPAKTSTPEDFIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRRAIADMLRACKEAAYHPEVAPDVRLRALHYGRECANGYLELLDHVLLTLQKPSPELKQQLTGHSKRVAGSVTELIQAAEAMKGTEWVDPEDPTVIAENELLGAAAAIEAAAKKLEQLKPRAKPKEADESLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANALDDGQWSQGLISAARMVAAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVKAAQKAAAFEEQENETVVVKEKMVGGIAQIIAAQEEMLRKERELEEARKKLAQIRQQQYKFLPSELRDEH 926 13.6 - 54 54 26 26 0.845 0.749 0.802 36 36 36 * * * 0.798666666666667 0.0480867272054705 sp|Q9Y490|TLN1_HUMAN 100.00 0.0 gi|223029410|ref|NP_006280.3| talin-1 [Homo sapiens] >gi|81175200|sp|Q9Y490.3|TLN1_HUMAN RecName: Full=Talin-1 >gi|119578756|gb|EAW58352.1| talin 1, isoform CRA_a [Homo sapiens] 100.00 0.0 sp|Q9Y490|TLN1_HUMAN Talin-1 OS=Homo sapiens GN=TLN1 PE=1 SV=3 99.86 0.0 G3QWY0 G3QWY0_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=TLN1 PE=4 SV=1 - - - - - - - K06271|1|0.0|4656|hsa:7094|talin GO:0007411//axon guidance;GO:0030168//platelet activation;GO:0007155//cell adhesion;GO:0007043//cell-cell junction assembly;GO:0006928//cellular component movement;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0006936//muscle contraction;GO:0007044//cell-substrate junction assembly;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0002576//platelet degranulation;GO:0030866//cortical actin cytoskeleton organization GO:0030274//LIM domain binding;GO:0003779//actin binding;GO:0017166//vinculin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005158//insulin receptor binding GO:0005925//focal adhesion;GO:0005911//cell-cell junction;GO:0032587//ruffle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005813//centrosome 36 tr|B4DFW1|B4DFW1_HUMAN cDNA FLJ52457, highly similar to Protein NOV homolog OS=Homo sapiens PE=2 SV=1 46847 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDSLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM 172 7.9 1 7 7 2 2 0.723 0.693 0.654 3 5 5 * - * 0.69 0.0345976877840124 tr|B4DFW1|B4DFW1_HUMAN 100.00 6e-172 gi|194376852|dbj|BAG57572.1| unnamed protein product [Homo sapiens] 95.52 1e-169 sp|P48745|NOV_HUMAN Protein NOV homolog OS=Homo sapiens GN=NOV PE=1 SV=1 100.00 2e-171 B4DFW1 B4DFW1_HUMAN cDNA FLJ52457, highly similar to Protein NOV homolog OS=Homo sapiens PE=2 SV=1 - - - - - - - K06827|1|4e-86|318|acs:100562863|connective tissue growth factor GO:0007411//axon guidance;GO:0010468//regulation of gene expression;GO:0001558//regulation of cell growth;GO:0060666//dichotomous subdivision of terminal units involved in salivary gland branching GO:0017154//semaphorin receptor activity;GO:0005520//insulin-like growth factor binding;GO:0008083//growth factor activity GO:0043231//intracellular membrane-bounded organelle;GO:0030424//axon;GO:0002116//semaphorin receptor complex;GO:0016021//integral to membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body;GO:0031012//extracellular matrix;GO:0005576//extracellular region;GO:0005886//plasma membrane 37 sp|P14174|MIF_HUMAN Macrophage migration inhibitory factor OS=Homo sapiens GN=MIF PE=1 SV=4 >tr|I4AY87|I4AY87_HUMAN Macrophage migration inhibitory factor (Fragment) OS=Homo sapiens PE=2 SV=1 13856 MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA 207 7.8 - 34 34 1 1 0.844 0.681 0.601 21 21 20 - * * 0.708666666666667 0.12383995047372 sp|P14174|MIF_HUMAN 100.00 6e-63 gi|240104633|pdb|3HOF|A Chain A, Structure Of Macrophage Migration Inhibitory Factor (Mif) With Caffeic Acid At 1.9a Resolution >gi|240104634|pdb|3HOF|B Chain B, Structure Of Macrophage Migration Inhibitory Factor (Mif) With Caffeic Acid At 1.9a Resolution >gi|240104635|pdb|3HOF|C Chain C, Structure Of Macrophage Migration Inhibitory Factor (Mif) With Caffeic Acid At 1.9a Resolution 100.00 1e-63 sp|Q4R549|MIF_MACFA Macrophage migration inhibitory factor OS=Macaca fascicularis GN=MIF PE=3 SV=3 100.00 3e-31 H2QLD1 H2QLD1_PANTR Uncharacterized protein OS=Pan troglodytes GN=MIF PE=4 SV=1 - - - - - - - K07253|1|9e-64|241|mcc:574298|phenylpyruvate tautomerase [EC:5.3.2.1] GO:0006954//inflammatory response;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0048146//positive regulation of fibroblast proliferation;GO:0007506//gonadal mesoderm development;GO:0007530//sex determination;GO:0050918//positive chemotaxis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0001546//preantral ovarian follicle growth;GO:0043030//regulation of macrophage activation;GO:0014070//response to organic cyclic compound;GO:0071157//negative regulation of cell cycle arrest;GO:0090344//negative regulation of cell aging;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0030890//positive regulation of B cell proliferation;GO:0045087//innate immune response;GO:0001516//prostaglandin biosynthetic process;GO:0010629//negative regulation of gene expression;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0050715//positive regulation of cytokine secretion;GO:0030154//cell differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0010739//positive regulation of protein kinase A signaling cascade;GO:0010628//positive regulation of gene expression;GO:0042493//response to drug;GO:0043066//negative regulation of apoptotic process;GO:0001655//urogenital system development;GO:0001880//Mullerian duct regression;GO:0070207//protein homotrimerization GO:0008083//growth factor activity;GO:0005160//transforming growth factor beta receptor binding;GO:0005125//cytokine activity;GO:0004167//dopachrome isomerase activity;GO:0043498//cell surface binding;GO:0050178//phenylpyruvate tautomerase activity;GO:0005179//hormone activity;GO:0042056//chemoattractant activity GO:0009986//cell surface;GO:0005615//extracellular space;GO:0005737//cytoplasm 38 tr|E9PNW4|E9PNW4_HUMAN CD59 glycoprotein OS=Homo sapiens GN=CD59 PE=1 SV=1 14733 MGIQGGSVLFGLLLVLAVFCHSGHSLQCYNCPNPTADCKTAVNCSSDFDACLITKAGLQVYNKCWKFEHCNFNDVTTRLRENELTYYCCKKDLCNFNEQLENGSEPGA 88 20.4 2 6 6 2 2 0.628 0.738 0.463 6 6 6 * - * 0.609666666666667 0.138413631313297 tr|E9PNW4|E9PNW4_HUMAN 100.00 4e-38 gi|157830573|pdb|1CDQ|A Chain A, Structure Of A Soluble, Glycosylated Form Of The Human Complement Regulatory Protein Cd59 >gi|157830574|pdb|1CDR|A Chain A, Structure Of A Soluble, Glycosylated Form Of The Human Complement Regulatory Protein Cd59 >gi|157830575|pdb|1CDS|A Chain A, Structure Of A Soluble, Glycosylated Form Of The Human Complement Regulatory Protein Cd59 100.00 5e-47 sp|P13987|CD59_HUMAN CD59 glycoprotein OS=Homo sapiens GN=CD59 PE=1 SV=1 100.00 6e-48 E9PNW4 E9PNW4_HUMAN CD59 glycoprotein OS=Homo sapiens GN=CD59 PE=4 SV=1 - - - - - - - K04008|1|5e-47|186|hsa:966|CD59 antigen GO:0007166//cell surface receptor signaling pathway;GO:0007596//blood coagulation GO:0005515//protein binding GO:0005576//extracellular region;GO:0031362//anchored to external side of plasma membrane 39 sp|P28074|PSB5_HUMAN Proteasome subunit beta type-5 OS=Homo sapiens GN=PSMB5 PE=1 SV=3 31371 MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP 90 15.6 - 4 4 3 3 0.396 0.975 0.695 4 4 4 * - * 0.688666666666667 0.289551952736177 sp|P28074|PSB5_HUMAN 100.00 8e-131 gi|31874085|emb|CAD97956.1| hypothetical protein [Homo sapiens] 100.00 9e-132 sp|Q5R8S2|PSB5_PONAB Proteasome subunit beta type-5 OS=Pongo abelii GN=PSMB5 PE=2 SV=3 100.00 3e-88 E9PAV2 E9PAV2_HUMAN Proteasome subunit beta type-5 OS=Homo sapiens GN=PSMB5 PE=3 SV=1 SPAC4A8.13c 270 2e-72 COG0638 20S proteasome, alpha and beta subunits O Posttranslational modification, protein turnover, chaperones ; K02737|1|9e-132|469|pon:100173015|20S proteasome subunit beta 5 [EC:3.4.25.1] GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0019048//virus-host interaction;GO:0000084//S phase of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0006979//response to oxidative stress;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0005515//protein binding;GO:0004298//threonine-type endopeptidase activity GO:0005654//nucleoplasm;GO:0005839//proteasome core complex;GO:0005829//cytosol 40 sp|Q6UVK1|CSPG4_HUMAN Chondroitin sulfate proteoglycan 4 OS=Homo sapiens GN=CSPG4 PE=1 SV=2 260193 MQSGPRPPLPAPGLALALTLTMLARLASAASFFGENHLEVPVATALTDIDLQLQFSTSQPEALLLLAAGPADHLLLQLYSGRLQVRLVLGQEELRLQTPAETLLSDSIPHTVVLTVVEGWATLSVDGFLNASSAVPGAPLEVPYGLFVGGTGTLGLPYLRGTSRPLRGCLHAATLNGRSLLRPLTPDVHEGCAEEFSASDDVALGFSGPHSLAAFPAWGTQDEGTLEFTLTTQSRQAPLAFQAGGRRGDFIYVDIFEGHLRAVVEKGQGTVLLHNSVPVADGQPHEVSVHINAHRLEISVDQYPTHTSNRGVLSYLEPRGSLLLGGLDAEASRHLQEHRLGLTPEATNASLLGCMEDLSVNGQRRGLREALLTRNMAAGCRLEEEEYEDDAYGHYEAFSTLAPEAWPAMELPEPCVPEPGLPPVFANFTQLLTISPLVVAEGGTAWLEWRHVQPTLDLMEAELRKSQVLFSVTRGARHGELELDIPGAQARKMFTLLDVVNRKARFIHDGSEDTSDQLVLEVSVTARVPMPSCLRRGQTYLLPIQVNPVNDPPHIIFPHGSLMVILEHTQKPLGPEVFQAYDPDSACEGLTFQVLGTSSGLPVERRDQPGEPATEFSCRELEAGSLVYVHRGGPAQDLTFRVSDGLQASPPATLKVVAIRPAIQIHRSTGLRLAQGSAMPILPANLSVETNAVGQDVSVLFRVTGALQFGELQKQGAGGVEGAEWWATQAFHQRDVEQGRVRYLSTDPQHHAYDTVENLALEVQVGQEILSNLSFPVTIQRATVWMLRLEPLHTQNTQQETLTTAHLEATLEEAGPSPPTFHYEVVQAPRKGNLQLQGTRLSDGQGFTQDDIQAGRVTYGATARASEAVEDTFRFRVTAPPYFSPLYTFPIHIGGDPDAPVLTNVLLVVPEGGEGVLSADHLFVKSLNSASYLYEVMERPRHGRLAWRGTQDKTTMVTSFTNEDLLRGRLVYQHDDSETTEDDIPFVATRQGESSGDMAWEEVRGVFRVAIQPVNDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADSGFADAQLVLTRKDLLFGSIVAVDEPTRPIYRFTQEDLRKRRVLFVHSGADRGWIQLQVSDGQHQATALLEVQASEPYLRVANGSSLVVPQGGQGTIDTAVLHLDTNLDIRSGDEVHYHVTAGPRWGQLVRAGQPATAFSQQDLLDGAVLYSHNGSLSPRDTMAFSVEAGPVHTDATLQVTIALEGPLAPLKLVRHKKIYVFQGEAAEIRRDQLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRGALADEPPSLDPVQSFSQEAVDTGRVLYLHSRPEAWSDAFSLDVASGLGAPLEGVLVELEVLPAAIPLEAQNFSVPEGGSLTLAPPLLRVSGPYFPTLLGLSLQVLEPPQHGALQKEDGPQARTLSAFSWRMVEEQLIRYVHDGSETLTDSFVLMANASEMDRQSHPVAFTVTVLPVNDQPPILTTNTGLQMWEGATAPIPAEALRSTDGDSGSEDLVYTIEQPSNGRVVLRGAPGTEVRSFTQAQLDGGLVLFSHRGTLDGGFRFRLSDGEHTSPGHFFRVTAQKQVLLSLKGSQTLTVCPGSVQPLSSQTLRASSSAGTDPQLLLYRVVRGPQLGRLFHAQQDSTGEALVNFTQAEVYAGNILYEHEMPPEPFWEAHDTLELQLSSPPARDVAATLAVAVSFEAACPQRPSHLWKNKGLWVPEGQRARITVAALDASNLLASVPSPQRSEHDVLFQVTQFPSRGQLLVSEEPLHAGQPHFLQSQLAAGQLVYAHGGGGTQQDGFHFRAHLQGPAGASVAGPQTSEAFAITVRDVNERPPQPQASVPLRLTRGSRAPISRAQLSVVDPDSAPGEIEYEVQRAPHNGFLSLVGGGLGPVTRFTQADVDSGRLAFVANGSSVAGIFQLSMSDGASPPLPMSLAVDILPSAIEVQLRAPLEVPQALGRSSLSQQQLRVVSDREEPEAAYRLIQGPQYGHLLVGGRPTSAFSQFQIDQGEVVFAFTNFSSSHDHFRVLALARGVNASAVVNVTVRALLHVWAGGPWPQGATLRLDPTVLDAGELANRTGSVPRFRLLEGPRHGRVVRVPRARTEPGGSQLVEQFTQQDLEDGRLGLEVGRPEGRAPGPAGDSLTLELWAQGVPPAVASLDFATEPYNAARPYSVALLSVPEAARTEAGKPESSTPTGEPGPMASSPEPAVAKGGFLSFLEANMFSVIIPMCLVLLLLALILPLLFYLRKRNKTGKHDVQVLTAKPRNGLAGDTETFRKVEPGQAIPLTAVPGQGPPPGGQPDPELLQFCRTPNPALKNGQYWV 654 9.8 - 35 35 16 16 0.763 0.614 0.715 18 17 16 * * * 0.697333333333333 0.0760548048010994 sp|Q6UVK1|CSPG4_HUMAN 100.00 0.0 gi|34148711|gb|AAQ62842.1| melanoma chondroitin sulfate proteoglycan [Homo sapiens] 100.00 0.0 sp|Q6UVK1|CSPG4_HUMAN Chondroitin sulfate proteoglycan 4 OS=Homo sapiens GN=CSPG4 PE=1 SV=2 100.00 7e-150 A2VCL1 A2VCL1_HUMAN CSPG4 protein (Fragment) OS=Homo sapiens GN=CSPG4 PE=2 SV=1 - - - - - - - K08115|1|0.0|4180|hsa:1464|chondroitin sulfate proteoglycan 4 GO:0001525//angiogenesis;GO:0030207//chondroitin sulfate catabolic process;GO:0048771//tissue remodeling;GO:0008283//cell proliferation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008347//glial cell migration;GO:0048663//neuron fate commitment;GO:0005975//carbohydrate metabolic process;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0044281//small molecule metabolic process;GO:0016322//neuron remodeling;GO:0000187//activation of MAPK activity;GO:0035556//intracellular signal transduction;GO:0030208//dermatan sulfate biosynthetic process GO:0004871//signal transducer activity;GO:0019901//protein kinase binding;GO:0005518//collagen binding GO:0005576//extracellular region;GO:0009986//cell surface;GO:0005796//Golgi lumen;GO:0031258//lamellipodium membrane;GO:0043202//lysosomal lumen;GO:0005887//integral to plasma membrane;GO:0016324//apical plasma membrane 41 sp|Q13219|PAPP1_HUMAN Pappalysin-1 OS=Homo sapiens GN=PAPPA PE=1 SV=3 204506 MRLWSWVLHLGLLSAALGCGLAERPRRARRDPRAGRPPRPAAGPATCATRAARGRRASPPPPPPPGGAWEAVRVPRRRQQREARGATEEPSPPSRALYFSGRGEQLRLRADLELPRDAFTLQVWLRAEGGQRSPAVITGLYDKCSYISRDRGWVVGIHTISDQDNKDPRYFFSLKTDRARQVTTINAHRSYLPGQWVYLAATYDGQFMKLYVNGAQVATSGEQVGGIFSPLTQKCKVLMLGGSALNHNYRGYIEHFSLWKVARTQREILSDMETHGAHTALPQLLLQENWDNVKHAWSPMKDGSSPKVEFSNAHGFLLDTSLEPPLCGQTLCDNTEVIASYNQLSSFRQPKVVRYRVVNLYEDDHKNPTVTREQVDFQHHQLAEAFKQYNISWELDVLEVSNSSLRRRLILANCDISKIGDENCDPECNHTLTGHDGGDCRHLRHPAFVKKQHNGVCDMDCNYERFNFDGGECCDPEITNVTQTCFDPDSPHRAYLDVNELKNILKLDGSTHLNIFFAKSSEEELAGVATWPWDKEALMHLGGIVLNPSFYGMPGHTHTMIHEIGHSLGLYHVFRGISEIQSCSDPCMETEPSFETGDLCNDTNPAPKHKSCGDPGPGNDTCGFHSFFNTPYNNFMSYADDDCTDSFTPNQVARMHCYLDLVYQGWQPSRKPAPVALAPQVLGHTTDSVTLEWFPPIDGHFFERELGSACHLCLEGRILVQYASNASSPMPCSPSGHWSPREAEGHPDVEQPCKSSVRTWSPNSAVNPHTVPPACPEPQGCYLELEFLYPLVPESLTIWVTFVSTDWDSSGAVNDIKLLAVSGKNISLGPQNVFCDVPLTIRLWDVGEEVYGIQIYTLDEHLEIDAAMLTSTADTPLCLQCKPLKYKVVRDPPLQMDVASILHLNRKFVDMDLNLGSVYQYWVITISGTEESEPSPAVTYIHGSGYCGDGIIQKDQGEQCDDMNKINGDGCSLFCRQEVSFNCIDEPSRCYFHDGDGVCEEFEQKTSIKDCGVYTPQGFLDQWASNASVSHQDQQCPGWVIIGQPAASQVCRTKVIDLSEGISQHAWYPCTISYPYSQLAQTTFWLRAYFSQPMVAAAVIVHLVTDGTYYGDQKQETISVQLLDTKDQSHDLGLHVLSCRNNPLIIPVVHDLSQPFYHSQAVRVSFSSPLVAISGVALRSFDNFDPVTLSSCQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTVRDIPHWLNPTRVERVVCTAGLKWYPHPALIHCVKGCEPFMGDNYCDAINNRAFCNYDGGDCCTSTVKTKKVTPFPMSCDLQGDCACRDPQAQEHSRKDLRGYSHG 403 7.9 - 20 20 10 10 0.805 0.567 0.630 15 15 15 * - * 0.667333333333333 0.123313962442756 sp|Q13219|PAPP1_HUMAN 100.00 3e-42 gi|194390314|dbj|BAG61919.1| unnamed protein product [Homo sapiens] 100.00 0.0 sp|Q13219|PAPP1_HUMAN Pappalysin-1 OS=Homo sapiens GN=PAPPA PE=1 SV=3 100.00 9e-42 E7EMD3 E7EMD3_HUMAN Pappalysin-1 OS=Homo sapiens GN=PAPPA PE=4 SV=2 - - - - - - - K07762|1|0.0|3204|hsa:5069|pappalysin-1 [EC:3.4.24.79] GO:0030154//cell differentiation;GO:0051384//response to glucocorticoid stimulus;GO:0007565//female pregnancy;GO:0006508//proteolysis GO:0004175//endopeptidase activity;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity GO:0005615//extracellular space;GO:0016020//membrane 42 tr|Q53F10|Q53F10_HUMAN UV excision repair protein RAD23 homolog B variant (Fragment) OS=Homo sapiens PE=2 SV=1 49532 MQVTLKTLQQQTFKIDIDPEETVKALKEKIESEKGKDAFPVAGQKLIYAGKILNDDTALKEYKIDEKNFVVVMVTKPKAVSTPAPATTQQSAPASTTAVTSSTTTTVAQAPTPVPALAPTSTPASITPASATASSEPAPASAAKQEKPAEKPAETPVATSPTATDSTSGDSSRSNLFEDATSALVTGQSYENMVTEIMSMGYEREQVIAALRASFNNPDRGVEYLLMGIPGDRESQAVVDPPQAASTGVPQSSAVAAAAATTTATTTTTSSGGHPLEFLRNQPQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQEAGGQGGGGGGGSGGIAEAGSGHMNYIQVTPQEKEAIGRLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFDED 179 11.7 1 11 11 4 4 0.642 0.519 0.648 6 6 6 * - * 0.603 0.0728079665970696 tr|Q53F10|Q53F10_HUMAN 100.00 2e-38 gi|387849175|ref|NP_001248717.1| UV excision repair protein RAD23 homolog B [Macaca mulatta] 100.00 2e-39 sp|P54727|RD23B_HUMAN UV excision repair protein RAD23 homolog B OS=Homo sapiens GN=RAD23B PE=1 SV=1 100.00 7e-39 Q5W0S5 Q5W0S5_HUMAN RAD23 homolog B (S. cerevisiae) (Fragment) OS=Homo sapiens GN=RAD23B PE=2 SV=1 SPBC2D10.12 222 1e-57 COG5272 Ubiquitin O Posttranslational modification, protein turnover, chaperones ; K10839|1|2e-101|369|mcc:711328|UV excision repair protein RAD23 GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0000715//nucleotide-excision repair, DNA damage recognition GO:0031593//polyubiquitin binding;GO:0003697//single-stranded DNA binding GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0071942//XPC complex 43 tr|B7Z4B2|B7Z4B2_HUMAN cDNA FLJ56108, highly similar to Puromycin-sensitive aminopeptidase (EC 3.4.11.-) OS=Homo sapiens PE=2 SV=1 110166 MNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTTPSGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLENASGKPIAAVMNTWTKQMGFPLIYVEAEQVEDDRLLRLSQKKFCAGGSYVGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMNVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFANEPNYTVWSDLSCNLGILSTLLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFKDHVEGKQILSADLRSPVYLTVLKHGDGTTLDIMFKLHKQADMQEEKNRIERVLGATLLPDLIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELYNRYQGGFLISRLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQCCENILLNAAWLKRDAESIHQYLLQRKASPPTV 236 15.4 3 16 16 11 11 0.695 0.849 0.671 10 10 10 * - * 0.738333333333333 0.096588474122606 tr|B7Z4B2|B7Z4B2_HUMAN 100.00 0.0 gi|221041642|dbj|BAH12498.1| unnamed protein product [Homo sapiens] 99.76 0.0 sp|P55786|PSA_HUMAN Puromycin-sensitive aminopeptidase OS=Homo sapiens GN=NPEPPS PE=1 SV=2 100.00 0.0 B7Z4B2 B7Z4B2_HUMAN cDNA FLJ56108, highly similar to Puromycin-sensitive aminopeptidase (EC 3.4.11.-) OS=Homo sapiens PE=2 SV=1 SPBC1921.05 514 3e-145 COG0308 Aminopeptidase N E Amino acid transport and metabolism ; K08776|1|0.0|1657|hsa:9520|puromycin-sensitive aminopeptidase [EC:3.4.11.-] GO:0071456//cellular response to hypoxia;GO:0000209//protein polyubiquitination;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0006508//proteolysis GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity GO:0005634//nucleus;GO:0005829//cytosol 44 sp|O00151|PDLI1_HUMAN PDZ and LIM domain protein 1 OS=Homo sapiens GN=PDLIM1 PE=1 SV=4 >tr|V9HW92|V9HW92_HUMAN Epididymis secretory protein Li 112 OS=Homo sapiens GN=HEL-S-112 PE=2 SV=1 43502 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQPPSSLVIDKESEVYKMLQEKQELNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYCEKHARERVTPPEGYEVVTVFPK 244 21.6 - 13 13 5 5 0.844 0.671 0.518 9 9 9 - * * 0.677666666666667 0.163102217438431 sp|O00151|PDLI1_HUMAN 100.00 8e-159 gi|119570397|gb|EAW50012.1| PDZ and LIM domain 1 (elfin), isoform CRA_d [Homo sapiens] 100.00 0.0 sp|O00151|PDLI1_HUMAN PDZ and LIM domain protein 1 OS=Homo sapiens GN=PDLIM1 PE=1 SV=4 100.00 4e-175 H2Q2B3 H2Q2B3_PANTR Uncharacterized protein (Fragment) OS=Pan troglodytes GN=ENSG00000107438 PE=4 SV=1 - - - - - - - K08202|1|7e-16|85.1|oaa:100079308|MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5!K09374|2|2e-06|53.9|mdo:100016250|LIM homeobox protein 3/4 GO:0001666//response to hypoxia;GO:0006979//response to oxidative stress;GO:0006355//regulation of transcription, DNA-dependent GO:0008270//zinc ion binding;GO:0003713//transcription coactivator activity GO:0005856//cytoskeleton;GO:0005667//transcription factor complex;GO:0005737//cytoplasm 45 tr|A0A087WVQ6|A0A087WVQ6_HUMAN Clathrin heavy chain OS=Homo sapiens GN=CLTC PE=1 SV=1 223516 MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKGIKESGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDEEPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNFSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGYTAPPYGQPQPGFGYSM 897 14.5 1 49 49 19 19 0.736 0.697 0.686 33 34 33 * - * 0.706333333333333 0.0262741951985847 tr|A0A087WVQ6|A0A087WVQ6_HUMAN 100.00 0.0 gi|119614803|gb|EAW94397.1| clathrin, heavy polypeptide (Hc), isoform CRA_c [Homo sapiens] 99.70 0.0 sp|P49951|CLH1_BOVIN 99.94 0.0 G7PUH3 G7PUH3_MACFA Putative uncharacterized protein OS=Macaca fascicularis GN=EGM_07783 PE=4 SV=1 - - - - - - - K04646|1|0.0|3393|ecb:100057364|clathrin heavy chain GO:0007411//axon guidance;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0033572//transferrin transport;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0016044//cellular membrane organization;GO:0006886//intracellular protein transport;GO:0007030//Golgi organization;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0031623//receptor internalization;GO:0090307//spindle assembly involved in mitosis;GO:0006892//post-Golgi vesicle-mediated transport GO:0030506//ankyrin binding;GO:0005198//structural molecule activity;GO:0008022//protein C-terminus binding;GO:0031072//heat shock protein binding;GO:0042277//peptide binding GO:0030132//clathrin coat of coated pit;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0042470//melanosome;GO:0005829//cytosol;GO:0005819//spindle;GO:0030315//T-tubule;GO:0031523//Myb complex;GO:0005739//mitochondrion 46 tr|A0A024R889|A0A024R889_HUMAN Spectrin, alpha, non-erythrocytic 1 (Alpha-fodrin), isoform CRA_g OS=Homo sapiens GN=SPTAN1 PE=4 SV=1 342803 MDPSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQIASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKAPIVTSEELGQDLEHVEVLQKKFEEFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGKLFGAAEVQRFNRDVDETISWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKVKALCAEADRLQQSHPLSATQIQVKREELITNWEQIRTLAAERHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELASDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLAAGHYASDEVREKLTVLSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKDEVAARMNEVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQEQIDNQYHSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDMDDEESWIKEKKLLVGSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHVQSKAIEARHASLMKRWSQLLANSAARKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKHQEIRAMRSQLKKIEDLGAAMEEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDPEFEAILDTVDPNRDGHVSLQEYMAFMISRETENVKSSEEIESAFRALSSEGKPYVTKEELYQNLTREQADYCVSHMKPYVDGKGRELPTAFDYVEFTRSLFVN 630 14.6 1 48 48 30 30 0.773 0.726 0.668 31 31 28 * * * 0.722333333333333 0.0525959440768329 tr|A0A024R889|A0A024R889_HUMAN 100.00 0.0 gi|119608211|gb|EAW87805.1| spectrin, alpha, non-erythrocytic 1 (alpha-fodrin), isoform CRA_a [Homo sapiens] 99.11 0.0 sp|Q13813|SPTN1_HUMAN 99.92 0.0 Q9UG16 Q9UG16_HUMAN Putative uncharacterized protein DKFZp564P0562 (Fragment) OS=Homo sapiens GN=DKFZp564P0562 PE=2 SV=1 SPAC3A12.14 62.4 1e-08 COG5126 Ca2+-binding protein (EF-Hand superfamily) TZDR Signal transduction mechanisms ; Cytoskeleton ; Cell cycle control, cell division, chromosome partitioning ; General function prediction only ; K06114|1|0.0|4826|hsa:6709|spectrin alpha GO:0007411//axon guidance;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0051693//actin filament capping GO:0030507//spectrin binding;GO:0005509//calcium ion binding;GO:0046982//protein heterodimerization activity;GO:0003779//actin binding;GO:0005516//calmodulin binding;GO:0005200//structural constituent of cytoskeleton GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0008091//spectrin;GO:0005829//cytosol;GO:0016328//lateral plasma membrane;GO:0032437//cuticular plate;GO:0030018//Z disc;GO:0005916//fascia adherens 47 tr|A0A087WWU8|A0A087WWU8_HUMAN Tropomyosin alpha-3 chain OS=Homo sapiens GN=TPM3 PE=1 SV=1 32412 MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLNEM 1245 24.7 3 89 28 6 4 0.553 0.623 0.704 12 13 13 * * - 0.626666666666667 0.0755667475370836 tr|A0A087WWU8|A0A087WWU8_HUMAN 100.00 3e-08 gi|21751375|dbj|BAC03956.1| unnamed protein product [Homo sapiens] 91.13 2e-83 sp|Q63610|TPM3_RAT Tropomyosin alpha-3 chain OS=Rattus norvegicus GN=Tpm3 PE=1 SV=2 100.00 9e-08 Q8NAG3 Q8NAG3_HUMAN Uncharacterized protein OS=Homo sapiens GN=TPM3 PE=2 SV=1 - - - - - - - K09290|1|4e-84|310|ssc:414388|tropomyosin 3 GO:0007420//brain development;GO:0030049//muscle filament sliding;GO:0006937//regulation of muscle contraction - GO:0005829//cytosol;GO:0030863//cortical cytoskeleton;GO:0002102//podosome;GO:0001725//stress fiber;GO:0005862//muscle thin filament tropomyosin;GO:0032154//cleavage furrow;GO:0031941//filamentous actin;GO:0030426//growth cone 48 sp|P26038|MOES_HUMAN Moesin OS=Homo sapiens GN=MSN PE=1 SV=3 >tr|V9HWC0|V9HWC0_HUMAN Epididymis luminal protein 70 OS=Homo sapiens GN=HEL70 PE=2 SV=1 87057 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQDEQDENGAEASADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM 967 22.4 - 82 34 13 7 0.794 0.786 0.793 28 29 28 * * * 0.791 0.00435889894354068 sp|P26038|MOES_HUMAN 100.00 0.0 gi|355704876|gb|EHH30801.1| Membrane-organizing extension spike protein, partial [Macaca mulatta] >gi|355757423|gb|EHH60948.1| Membrane-organizing extension spike protein, partial [Macaca fascicularis] 100.00 0.0 sp|P26038|MOES_HUMAN Moesin OS=Homo sapiens GN=MSN PE=1 SV=3 100.00 0.0 G1QHZ4 G1QHZ4_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=MSN PE=4 SV=1 - - - - - - - K05763|1|0.0|1039|mcc:711712|moesin GO:0022614//membrane to membrane docking;GO:2000401//regulation of lymphocyte migration;GO:0007159//leukocyte cell-cell adhesion GO:0005102//receptor binding;GO:0003779//actin binding;GO:0050839//cell adhesion molecule binding;GO:0019901//protein kinase binding;GO:0005200//structural constituent of cytoskeleton GO:0019898//extrinsic to membrane;GO:0009898//internal side of plasma membrane;GO:0031527//filopodium membrane;GO:0005856//cytoskeleton;GO:0005730//nucleolus;GO:0009986//cell surface;GO:0001931//uropod;GO:0005925//focal adhesion;GO:0030667//secretory granule membrane;GO:0016324//apical plasma membrane;GO:0031528//microvillus membrane 49 sp|P01023|A2MG_HUMAN Alpha-2-macroglobulin OS=Homo sapiens GN=A2M PE=1 SV=3 191992 MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDNEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA 776 8.5 - 61 34 10 8 0.584 0.647 0.700 19 18 18 * * - 0.643666666666667 0.058071794645364 sp|P01023|A2MG_HUMAN 100.00 0.0 gi|308153640|sp|P01023.3|A2MG_HUMAN RecName: Full=Alpha-2-macroglobulin; Short=Alpha-2-M; AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; Flags: Precursor 100.00 0.0 sp|P01023|A2MG_HUMAN Alpha-2-macroglobulin OS=Homo sapiens GN=A2M PE=1 SV=3 100.00 0.0 H0YGH4 H0YGH4_HUMAN Alpha-2-macroglobulin OS=Homo sapiens GN=A2M PE=4 SV=1 TM0984 74.7 1e-12 COG2373 Large extracellular alpha-helical protein R General function prediction only ; K03910|1|0.0|2947|hsa:2|alpha-2-macroglobulin GO:0030168//platelet activation;GO:0001869//negative regulation of complement activation, lectin pathway;GO:0010951//negative regulation of endopeptidase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007597//blood coagulation, intrinsic pathway;GO:0002576//platelet degranulation GO:0019966//interleukin-1 binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0043120//tumor necrosis factor binding;GO:0019959//interleukin-8 binding;GO:0019899//enzyme binding GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005829//cytosol 50 tr|B2RDY9|B2RDY9_HUMAN Adenylyl cyclase-associated protein OS=Homo sapiens PE=2 SV=1 65557 MADMQNLVERLERAVGRLEAVSHTSDMHRGYADSPSKAGAAPYVQAFDSLLAGPVAEYLKISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPISEQIKEVITFREKNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKKHVDWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSAGSGPPPPPPGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVNTTLQIKGKINSITVDNCKKLGLVFGDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG 297 10.7 5 13 13 4 4 0.578 0.594 0.538 9 9 9 * * * 0.57 0.0288444102037119 tr|B2RDY9|B2RDY9_HUMAN 100.00 0.0 gi|189055102|dbj|BAG38086.1| unnamed protein product [Homo sapiens] 98.53 0.0 sp|Q01518|CAP1_HUMAN Adenylyl cyclase-associated protein 1 OS=Homo sapiens GN=CAP1 PE=1 SV=5 100.00 0.0 B2RDY9 B2RDY9_HUMAN Adenylyl cyclase-associated protein OS=Homo sapiens PE=2 SV=1 - - - - - - - - GO:0050688//regulation of defense response to virus;GO:0034138//toll-like receptor 3 signaling pathway;GO:0007411//axon guidance;GO:0034142//toll-like receptor 4 signaling pathway;GO:0008063//Toll signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0030162//regulation of proteolysis;GO:0001667//ameboidal cell migration;GO:0030168//platelet activation;GO:0007163//establishment or maintenance of cell polarity;GO:0006898//receptor-mediated endocytosis;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0002576//platelet degranulation;GO:0032648//regulation of interferon-beta production;GO:0032480//negative regulation of type I interferon production;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0030036//actin cytoskeleton organization;GO:0006917//induction of apoptosis GO:0004871//signal transducer activity;GO:0031625//ubiquitin protein ligase binding;GO:0004842//ubiquitin-protein ligase activity;GO:0008270//zinc ion binding;GO:0031996//thioesterase binding;GO:0003779//actin binding GO:0005829//cytosol;GO:0030864//cortical actin cytoskeleton;GO:0009898//internal side of plasma membrane;GO:0005739//mitochondrion;GO:0035631//CD40 receptor complex;GO:0005768//endosome 51 tr|Q5TZP0|Q5TZP0_HUMAN Matrix metalloproteinase 1 (Interstitial collagenase) OS=Homo sapiens PE=2 SV=1 63549 MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGMQVEKRRNSGPVVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDRFYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN 3031 35.4 4 150 21 14 1 0.581 0.606 0.667 15 15 15 - * * 0.618 0.0442379927211894 tr|Q5TZP0|Q5TZP0_HUMAN 100.00 0.0 gi|54697154|gb|AAV38949.1| matrix metalloproteinase 1 (interstitial collagenase) [Homo sapiens] 99.79 0.0 sp|P03956|MMP1_HUMAN Interstitial collagenase OS=Homo sapiens GN=MMP1 PE=1 SV=3 100.00 0.0 Q5TZP0 Q5TZP0_HUMAN Matrix metalloproteinase 1 (Interstitial collagenase) OS=Homo sapiens PE=2 SV=1 - - - - - - - K01388|1|0.0|973|ptr:451510|matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7] GO:0022617//extracellular matrix disassembly;GO:0050900//leukocyte migration;GO:0006508//proteolysis;GO:0019048//virus-host interaction;GO:0030574//collagen catabolic process;GO:0007596//blood coagulation GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0004222//metalloendopeptidase activity GO:0005578//proteinaceous extracellular matrix 52 tr|B2R582|B2R582_HUMAN cDNA, FLJ92374, highly similar to Homo sapiens C-type lectin domain family 3, member B (CLEC3B), mRNA OS=Homo sapiens PE=2 SV=1 28093 MELWGAYLLLCLFSLLTQVTTEPPTQKPKKIVNAKKDVVNTKMFEVLKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLSTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV 826 22.8 2 28 28 4 4 0.323 0.261 0.292 24 24 22 * * - 0.292 0.031 tr|B2R582|B2R582_HUMAN 100.00 1e-116 gi|189065306|dbj|BAG35029.1| unnamed protein product [Homo sapiens] 99.01 4e-116 sp|P05452|TETN_HUMAN Tetranectin OS=Homo sapiens GN=CLEC3B PE=1 SV=3 100.00 6e-75 Q68DS3 Q68DS3_HUMAN Putative uncharacterized protein DKFZp686H17246 (Fragment) OS=Homo sapiens GN=DKFZp686H17246 PE=2 SV=1 - - - - - - - K12589|1|1e-115|415|pon:100458989|exosome complex component RRP42!K10068|5|1e-13|76.3|bta:282072|surfactant, pulmonary-associated protein D GO:0001501//skeletal system development;GO:0030282//bone mineralization;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0010756//positive regulation of plasminogen activation GO:0005509//calcium ion binding;GO:0036143//kringle domain binding;GO:0008201//heparin binding GO:0005615//extracellular space;GO:0001652//granular component;GO:0031012//extracellular matrix;GO:0005737//cytoplasm 53 tr|B4DH02|B4DH02_HUMAN cDNA FLJ50510, highly similar to Heat shock 70 kDa protein 4 OS=Homo sapiens PE=2 SV=1 120101 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDTTQIAGLNCLRLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVFSKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMDID 276 13.7 3 16 12 8 7 0.654 0.708 0.722 8 8 8 * * - 0.694666666666667 0.0359072880253206 tr|B4DH02|B4DH02_HUMAN 100.00 0.0 gi|194378426|dbj|BAG57963.1| unnamed protein product [Homo sapiens] 99.88 0.0 sp|P34932|HSP74_HUMAN Heat shock 70 kDa protein 4 OS=Homo sapiens GN=HSPA4 PE=1 SV=4 100.00 0.0 B4E354 B4E354_HUMAN cDNA FLJ55293, highly similar to Heat shock 70 kDa protein 4 OS=Homo sapiens PE=2 SV=1 YBR169c 456 6e-128 COG0443 Molecular chaperone O Posttranslational modification, protein turnover, chaperones ; K09489|1|0.0|1627|hsa:3308|heat shock 70kDa protein 4 GO:0009408//response to heat;GO:0045040//protein import into mitochondrial outer membrane;GO:0032092//positive regulation of protein binding;GO:0006986//response to unfolded protein;GO:0051131//chaperone-mediated protein complex assembly GO:0005524//ATP binding GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005811//lipid particle 54 tr|Q7Z759|Q7Z759_HUMAN CCT8 protein OS=Homo sapiens GN=CCT8 PE=2 SV=1 66145 MNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKAHEILPNLVCCSAKNLRDIDEVSSLLRTSIMSKQYGNEVFLAKLIAQACVSIFPDSGHFNVDNIRVCKILGSGISSSSVLHGMVFKKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKDWDDDQND 158 10.7 2 6 6 4 4 0.783 0.528 0.413 4 4 3 - * * 0.574666666666667 0.189362967164473 tr|Q7Z759|Q7Z759_HUMAN 100.00 0.0 gi|31418053|gb|AAH12584.1| CCT8 protein [Homo sapiens] >gi|119630331|gb|EAX09926.1| chaperonin containing TCP1, subunit 8 (theta), isoform CRA_c [Homo sapiens] 100.00 0.0 sp|Q5RAP1|TCPQ_PONAB T-complex protein 1 subunit theta OS=Pongo abelii GN=CCT8 PE=2 SV=3 100.00 0.0 G3QU21 G3QU21_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=CCT8 PE=3 SV=1 YJL008c 463 3e-130 COG0459 Chaperonin GroEL (HSP60 family) O Posttranslational modification, protein turnover, chaperones ; K09500|1|0.0|918|pon:100172606|T-complex protein 1 subunit theta GO:0051084//'de novo' posttranslational protein folding GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0042623//ATPase activity, coupled GO:0045111//intermediate filament cytoskeleton;GO:0016235//aggresome;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005874//microtubule 55 tr|B2MV14|B2MV14_HUMAN Truncated lactoferrin OS=Homo sapiens GN=LTF PE=3 SV=1 75410 MKLVFLVLLFLGALGLCLAGRRRRSVQWCTVSQPEATKCFQWQRNMRRVRGPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGGSFQLNELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCVPGADKGQFPNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGFSRVPPRIDSGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWSGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQTGSCKFDEYFSQSCAPGSDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNMRHGLRI 509 3.6 11 25 25 2 2 0.694 0.605 0.688 14 14 14 * * * 0.662333333333333 0.049742671151973 tr|B2MV14|B2MV14_HUMAN 100.00 0.0 gi|28948741|pdb|1N76|A Chain A, Crystal Structure Of Human Seminal Lactoferrin At 3.4 A Resolution 99.64 0.0 sp|P02788|TRFL_HUMAN Lactotransferrin OS=Homo sapiens GN=LTF PE=1 SV=6 100.00 0.0 B2MV13 B2MV13_HUMAN Lactoferrin OS=Homo sapiens GN=LTF PE=4 SV=1 - - - - - - - K14736|1|0.0|713|bta:280705|transferrin GO:0042742//defense response to bacterium;GO:0090382//phagosome maturation;GO:0006508//proteolysis;GO:0033214//iron assimilation by chelation and transport;GO:0006959//humoral immune response;GO:0006826//iron ion transport;GO:0052572//response to host immune response GO:0008199//ferric iron binding;GO:0005515//protein binding;GO:0004252//serine-type endopeptidase activity;GO:0008201//heparin binding GO:0030141//secretory granule;GO:0097013//phagocytic vesicle lumen;GO:0005576//extracellular region 56 tr|A0A087WV23|A0A087WV23_HUMAN SH3 domain-binding glutamic acid-rich-like protein 3 OS=Homo sapiens GN=SH3BGRL3 PE=1 SV=1 26186 MHQTCVRLEREASARPSPGPVLPPRPLPSHTELQIREGPKRTIRAAAEGAPCVGRVRCAPGNRGGREGASGVRGGVAQVPPRLPAPPIGPERDDLAGGAGRKPLPSTAAASSPGSAAAATAALCPPARLSTPSMSGLRVYSTSVTGSREIKSQQSEVTRILDGKRIQYQLVDISQDNALRDEMRALAGNPKATPPQIVNGDQYCGDYELFVEAVEQNTLQEFLKLA 278 8.4 4 18 18 2 2 0.483 0.564 0.541 13 15 15 - * * 0.529333333333333 0.0417412665516193 tr|A0A087WV23|A0A087WV23_HUMAN 100.00 5e-38 gi|444706308|gb|ELW47651.1| SH3 domain-binding glutamic acid-rich-like protein 3 [Tupaia chinensis] 100.00 1e-48 sp|Q9H299|SH3L3_HUMAN SH3 domain-binding glutamic acid-rich-like protein 3 OS=Homo sapiens GN=SH3BGRL3 PE=1 SV=1 100.00 3e-47 G5AUR1 G5AUR1_HETGA SH3 domain-binding glutamic acid-rich-like protein 3 OS=Heterocephalus glaber GN=GW7_08411 PE=4 SV=1 - - - - - - - K01047|1|5e-09|61.6|nve:NEMVE_v1g199410|phospholipase A2 [EC:3.1.1.4] GO:0045454//cell redox homeostasis;GO:0055114//oxidation-reduction process GO:0009055//electron carrier activity;GO:0015035//protein disulfide oxidoreductase activity GO:0005737//cytoplasm;GO:0005634//nucleus 57 tr|Q9UNM1|Q9UNM1_HUMAN Chaperonin 10-related protein (Fragment) OS=Homo sapiens GN=EPFP1 PE=3 SV=1 13635 AGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTKVVLDDKDYFLFRDGDILG 147 45.4 1 12 12 4 4 0.704 0.939 0.655 7 7 6 * - * 0.766 0.151812384211566 tr|Q9UNM1|Q9UNM1_HUMAN 100.00 3e-41 gi|297300735|ref|XP_002805650.1| PREDICTED: 10 kDa heat shock protein, mitochondrial-like isoform 2 [Macaca mulatta] 100.00 5e-42 sp|P61604|CH10_HUMAN 10 kDa heat shock protein, mitochondrial OS=Homo sapiens GN=HSPE1 PE=1 SV=2 100.00 2e-40 F7BG90 F7BG90_MACMU 10 kDa heat shock protein, mitochondrial OS=Macaca mulatta GN=LOC720015 PE=3 SV=1 SPCC550.06c 85.5 2e-17 COG0234 Co-chaperonin GroES (HSP10) O Posttranslational modification, protein turnover, chaperones ; K04078|1|7e-43|171|ecb:100629260|chaperonin GroES GO:0006457//protein folding;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006986//response to unfolded protein GO:0051087//chaperone binding;GO:0005524//ATP binding;GO:0051082//unfolded protein binding GO:0005759//mitochondrial matrix 58 sp|O15144|ARPC2_HUMAN Actin-related protein 2/3 complex subunit 2 OS=Homo sapiens GN=ARPC2 PE=1 SV=1 >tr|Q53R19|Q53R19_HUMAN Actin related protein 2/3 complex, subunit 2, 34kDa, isoform CRA_a OS=Homo sapiens GN=ARPC2 PE=2 SV=1 42335 MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR 137 15.3 - 13 13 5 5 0.906 0.596 0.664 7 6 7 - * * 0.722 0.162935570088302 sp|O15144|ARPC2_HUMAN 100.00 2e-158 gi|332246685|ref|XP_003272483.1| PREDICTED: actin-related protein 2/3 complex subunit 2 [Nomascus leucogenys] 100.00 1e-177 sp|O15144|ARPC2_HUMAN Actin-related protein 2/3 complex subunit 2 OS=Homo sapiens GN=ARPC2 PE=1 SV=1 100.00 3e-58 H7C3F9 H7C3F9_HUMAN Actin-related protein 2/3 complex subunit 2 (Fragment) OS=Homo sapiens GN=ARPC2 PE=4 SV=1 - - - - - - - K05758|1|1e-177|622|mcc:700536|actin related protein 2/3 complex, subunit 2 GO:0006928//cellular component movement;GO:0030838//positive regulation of actin filament polymerization GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton GO:0005885//Arp2/3 protein complex;GO:0031252//cell leading edge;GO:0042995//cell projection;GO:0005925//focal adhesion;GO:0005794//Golgi apparatus 59 tr|D6RDU5|D6RDU5_HUMAN Septin-11 (Fragment) OS=Homo sapiens GN=SEPT11 PE=1 SV=1 54931 MNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKK 218 14.2 3 15 15 4 4 0.785 0.700 0.751 11 11 11 * - * 0.745333333333333 0.042782395133201 tr|D6RDU5|D6RDU5_HUMAN 100.00 0.0 gi|63991119|gb|AAY40922.1| unknown [Homo sapiens] 100.00 0.0 sp|Q8C1B7|SEP11_MOUSE Septin-11 OS=Mus musculus GN=Sept11 PE=1 SV=4 100.00 0.0 F7H547 F7H547_CALJA Uncharacterized protein OS=Callithrix jacchus GN=SEPT11 PE=3 SV=1 SPAC4F10.11 264 2e-70 COG5019 Septin family protein DZ Cell cycle control, cell division, chromosome partitioning ; Cytoskeleton ; K04557|1|8e-70|264|xla:779425|peanut-like protein 1 (cell division control related protein 1)!K13737|4|2e-68|259|acs:100556344|septin 1 GO:0051291//protein heterooligomerization;GO:0007049//cell cycle;GO:0051301//cell division GO:0005525//GTP binding;GO:0005515//protein binding GO:0043197//dendritic spine;GO:0030054//cell junction;GO:0030424//axon;GO:0001725//stress fiber;GO:0031105//septin complex;GO:0045202//synapse 60 tr|X6RJP6|X6RJP6_HUMAN Transgelin-2 (Fragment) OS=Homo sapiens GN=TAGLN2 PE=1 SV=1 25198 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQA 422 39.6 1 22 22 5 5 0.815 0.703 0.706 11 11 11 - * * 0.741333333333333 0.0638148363104798 tr|X6RJP6|X6RJP6_HUMAN 100.00 4e-107 gi|355558625|gb|EHH15405.1| hypothetical protein EGK_01490 [Macaca mulatta] 100.00 2e-107 sp|P37802|TAGL2_HUMAN Transgelin-2 OS=Homo sapiens GN=TAGLN2 PE=1 SV=3 100.00 4e-106 F6RKI4 F6RKI4_MACMU Transgelin-2 OS=Macaca mulatta GN=Mmu.3153 PE=2 SV=1 YOR367w 89.7 3e-18 COG5199 Calponin Z Cytoskeleton ; - GO:0007517//muscle organ development GO:0005515//protein binding GO:0031965//nuclear membrane;GO:0005886//plasma membrane 61 tr|M0QXF7|M0QXF7_HUMAN UPF0556 protein C19orf10 (Fragment) OS=Homo sapiens GN=C19orf10 PE=1 SV=1 11851 XHQHFTCTIWRPQGKSYLYFTQFKAEVRGAEIEYAMAYSKAAFERESDVPLKTEEFEVTKTAVISAPQEKGDDQPHWTDGETEA 126 42.9 2 11 11 3 3 0.734 0.683 0.670 6 6 6 - * * 0.695666666666667 0.0338279962949822 tr|M0QXF7|M0QXF7_HUMAN 100.00 5e-29 gi|3513302|gb|AAC33800.1| R33729_1, partial CDS [Homo sapiens] 95.45 9e-31 sp|Q969H8|CS010_HUMAN UPF0556 protein C19orf10 OS=Homo sapiens GN=C19orf10 PE=1 SV=1 97.30 3e-14 H2NX37 H2NX37_PONAB Uncharacterized protein (Fragment) OS=Pongo abelii GN=C19orf10 PE=4 SV=1 - - - - - - - - GO:0006987//activation of signaling protein activity involved in unfolded protein response - GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region 62 sp|P08572|CO4A2_HUMAN Collagen alpha-2(IV) chain OS=Homo sapiens GN=COL4A2 PE=1 SV=4 >tr|A0A024RDW8|A0A024RDW8_HUMAN Collagen, type IV, alpha 2, isoform CRA_a OS=Homo sapiens GN=COL4A2 PE=4 SV=1 193591 MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPEQSFQGSPSADTLKAGLIRTHISRCQVCMKNL 867 14.3 - 42 42 16 16 0.672 0.605 0.498 31 30 28 * * * 0.591666666666667 0.0877629382674335 sp|P08572|CO4A2_HUMAN 100.00 8e-133 gi|8101724|gb|AAF72631.1|AF258350_1 canstatin, partial [Homo sapiens] >gi|15217055|gb|AAK92479.1|AF400430_1 canstatin [Homo sapiens] >gi|38349537|gb|AAR18250.1| canstatin [Homo sapiens] >gi|38426265|gb|AAR20245.1| endogenous angiogenesis inhibitor [Homo sapiens] 100.00 0.0 sp|P08572|CO4A2_HUMAN Collagen alpha-2(IV) chain OS=Homo sapiens GN=COL4A2 PE=1 SV=4 100.00 0.0 E7EPD1 E7EPD1_HUMAN Canstatin OS=Homo sapiens GN=COL4A2 PE=4 SV=2 - - - - - - - K06237|1|0.0|1281|hsa:1284|collagen, type IV, alpha GO:0007411//axon guidance;GO:0016525//negative regulation of angiogenesis;GO:0006351//transcription, DNA-dependent;GO:0030198//extracellular matrix organization GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent GO:0005788//endoplasmic reticulum lumen;GO:0005587//collagen type IV 63 tr|A0A024RC87|A0A024RC87_HUMAN Ribonuclease/angiogenin inhibitor 1, isoform CRA_a OS=Homo sapiens GN=RNH1 PE=4 SV=1 56381 MSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEARCKDISSALRVNPALAELNLRSNELGDVGVHCVLQGLQTPSCKIQKLSLQNCCLTGAGCGVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLASVLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRDLCGIVASKASLRELALGSNKLGDVGMAELCPGLLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEGARLLCETLLEPGCQLESLWVKSCSFTAACCSHFSSVLAQNRFLLELQISNNRLEDAGVRELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAATLLANHSLRELDLSNNCLGDAGILQLVESVRQPGCLLEQLVLYDIYWSEEMEDRLQALEKDKPSLRVIS 222 11.8 1 14 14 4 4 0.693 0.640 0.780 8 8 8 * * * 0.704333333333333 0.0706847461149386 tr|A0A024RC87|A0A024RC87_HUMAN 100.00 0.0 gi|119622740|gb|EAX02335.1| ribonuclease/angiogenin inhibitor 1, isoform CRA_c [Homo sapiens] 100.00 0.0 sp|P13489|RINI_HUMAN Ribonuclease inhibitor OS=Homo sapiens GN=RNH1 PE=1 SV=2 100.00 2e-102 E9PIM9 E9PIM9_HUMAN Ribonuclease inhibitor (Fragment) OS=Homo sapiens GN=RNH1 PE=4 SV=1 - - - - - - - K12800|1|1e-55|218|acs:100552241|NACHT, LRR and PYD domains-containing protein 3 GO:0006264//mitochondrial DNA replication;GO:0006402//mRNA catabolic process;GO:0045765//regulation of angiogenesis GO:0003723//RNA binding;GO:0008428//ribonuclease inhibitor activity;GO:0000287//magnesium ion binding;GO:0004523//ribonuclease H activity;GO:0042803//protein homodimerization activity GO:0032311//angiogenin-PRI complex;GO:0005739//mitochondrion;GO:0005634//nucleus 64 tr|G9K388|G9K388_HUMAN YWHAE/FAM22A fusion protein (Fragment) OS=Homo sapiens GN=YWHAE/FAM22A fusion PE=2 SV=1 47320 RADPAGAAAAMDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTLPSTPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVV 734 18.0 2 41 23 6 4 0.859 0.716 0.777 17 18 18 * * * 0.784 0.071756532803641 tr|G9K388|G9K388_HUMAN 100.00 0.0 gi|365927536|gb|AEX07732.1| YWHAE/FAM22A fusion protein, partial [Homo sapiens] 100.00 8e-135 sp|P62262|1433E_SHEEP 14-3-3 protein epsilon OS=Ovis aries GN=YWHAE PE=1 SV=1 100.00 2e-133 G3RKZ8 G3RKZ8_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=YWHAE PE=3 SV=1 YDR099w 378 7e-105 COG5040 14-3-3 family protein T Signal transduction mechanisms ; K06630|1|9e-135|480|gga:417554|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein GO:0001764//neuron migration;GO:0035308//negative regulation of protein dephosphorylation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0021766//hippocampus development;GO:0006605//protein targeting;GO:0021987//cerebral cortex development;GO:0019048//virus-host interaction;GO:0035329//hippo signaling cascade;GO:0055114//oxidation-reduction process;GO:0000086//G2/M transition of mitotic cell cycle GO:0042826//histone deacetylase binding;GO:0050815//phosphoserine binding;GO:0004497//monooxygenase activity;GO:0019904//protein domain specific binding;GO:0008426//protein kinase C inhibitor activity;GO:0032403//protein complex binding GO:0042470//melanosome;GO:0005829//cytosol;GO:0033267//axon part;GO:0005871//kinesin complex;GO:0005739//mitochondrion 65 tr|B3VL17|B3VL17_HUMAN Beta globin (Fragment) OS=Homo sapiens PE=3 SV=1 14272 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTXRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPEXFR 478 18.1 - 37 37 4 4 0.930 0.684 0.620 16 16 16 - * * 0.744666666666667 0.163662253844108 tr|B3VL17|B3VL17_HUMAN 100.00 2e-53 gi|193244921|gb|ACF16774.1| beta globin [Homo sapiens] 98.10 5e-55 sp|P68873|HBB_PANTR Hemoglobin subunit beta OS=Pan troglodytes GN=HBB PE=1 SV=2 100.00 7e-53 B3VL17 B3VL17_HUMAN Beta globin (Fragment) OS=Homo sapiens PE=3 SV=1 - - - - - - - K13823|1|5e-55|212|ptr:450978|hemoglobin subunit beta GO:0042744//hydrogen peroxide catabolic process;GO:0051291//protein heterooligomerization;GO:0010942//positive regulation of cell death;GO:0015701//bicarbonate transport;GO:0008217//regulation of blood pressure;GO:0015671//oxygen transport;GO:0070293//renal absorption;GO:0030185//nitric oxide transport;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0044281//small molecule metabolic process;GO:0050880//regulation of blood vessel size;GO:0007596//blood coagulation GO:0004601//peroxidase activity;GO:0030492//hemoglobin binding;GO:0005344//oxygen transporter activity;GO:0019825//oxygen binding;GO:0031720//haptoglobin binding;GO:0020037//heme binding;GO:0005506//iron ion binding GO:0031838//haptoglobin-hemoglobin complex;GO:0005833//hemoglobin complex 66 tr|M0R009|M0R009_HUMAN Alpha-1B-glycoprotein (Fragment) OS=Homo sapiens GN=A1BG PE=4 SV=3 37179 LTCQAHLETPDFQLFKNGVAQEPVHLDSPAIKHQFLLTGDTQGRYRCRSGLSTGWTQLSKLLELTGPKSLPAPWLSMAPVSWITPGLKTTAVCRGVLRGVTFLLRREGDHEFLEVPEAQEDVEATFPVHQPGNYSCSYRTDGEGALSEPSATVTIEELGPGPGSWPHGCLGLMVAKEFGQRMPKEWKAAPPPPVLMHHGESSQVLHPGNKVTLTCVAPLSGVDFQLRRGEKELLVPRSSTSPDRIFFHLNAVALGDGGHYTCRYRLHDNQNGWSGDSAPVELILSDETLPAPEFSPEPESGRALRL 43 2.3 2 3 3 1 1 0.711 0.730 0.652 3 3 3 * * * 0.697666666666667 0.0406734966942029 tr|M0R009|M0R009_HUMAN 99.16 2e-62 gi|193786308|dbj|BAG51591.1| unnamed protein product [Homo sapiens] 90.52 6e-156 sp|P04217|A1BG_HUMAN Alpha-1B-glycoprotein OS=Homo sapiens GN=A1BG PE=1 SV=4 99.16 7e-62 B3KP79 B3KP79_HUMAN cDNA FLJ31323 fis, clone LIVER2000037, highly similar to Alpha-1B-glycoprotein OS=Homo sapiens PE=2 SV=1 - - - - - - - K06512|1|7e-12|71.6|ptr:450148|leukocyte immunoglobulin-like receptor - - GO:0005576//extracellular region 67 tr|B2R983|B2R983_HUMAN cDNA, FLJ94267, highly similar to Homo sapiens glutathione S-transferase omega 1 (GSTO1), mRNA OS=Homo sapiens PE=2 SV=1 35107 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGSSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL 278 23.7 1 23 23 6 6 0.560 0.781 0.500 6 6 6 * - * 0.613666666666667 0.147987612094166 tr|B2R983|B2R983_HUMAN 100.00 4e-139 gi|189053923|dbj|BAG36430.1| unnamed protein product [Homo sapiens] 99.59 1e-139 sp|P78417|GSTO1_HUMAN Glutathione S-transferase omega-1 OS=Homo sapiens GN=GSTO1 PE=1 SV=2 100.00 1e-138 B2R983 B2R983_HUMAN cDNA, FLJ94267, highly similar to Homo sapiens glutathione S-transferase omega 1 (GSTO1), mRNA OS=Homo sapiens PE=2 SV=1 NMB1953 85.9 5e-17 COG0625 Glutathione S-transferase O Posttranslational modification, protein turnover, chaperones ; K00799|1|3e-138|491|pon:100447725|glutathione S-transferase [EC:2.5.1.18] GO:0042178//xenobiotic catabolic process;GO:0019853//L-ascorbic acid biosynthetic process;GO:0071243//cellular response to arsenic-containing substance GO:0004364//glutathione transferase activity;GO:0050610//methylarsonate reductase activity;GO:0045174//glutathione dehydrogenase (ascorbate) activity GO:0005829//cytosol 68 sp|Q12841|FSTL1_HUMAN Follistatin-related protein 1 OS=Homo sapiens GN=FSTL1 PE=1 SV=1 44317 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNETAINITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQETAEKTKRVSTKEI 1257 35.1 - 96 89 10 9 0.734 0.583 0.637 50 50 51 * * - 0.651333333333333 0.0765136153461156 sp|Q12841|FSTL1_HUMAN 100.00 1e-159 gi|355746446|gb|EHH51060.1| hypothetical protein EGM_10384, partial [Macaca fascicularis] 100.00 3e-160 sp|Q12841|FSTL1_HUMAN Follistatin-related protein 1 OS=Homo sapiens GN=FSTL1 PE=1 SV=1 100.00 3e-67 Q9BZQ0 Q9BZQ0_HUMAN Follistatin-related protein (Fragment) OS=Homo sapiens PE=2 SV=1 - - - - - - - K06254|1|7e-11|68.2|tca:100141763|agrin GO:0030509//BMP signaling pathway GO:0008201//heparin binding;GO:0005509//calcium ion binding GO:0005615//extracellular space 69 sp|O43707|ACTN4_HUMAN Alpha-actinin-4 OS=Homo sapiens GN=ACTN4 PE=1 SV=2 123193 MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDALGSLTHSRREALEKTEKQLEAIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANVVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLDLLEQQHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQGEAEFNRIMSLVDPNHSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAVPGALDYKSFSTALYGESDL 4367 43.2 - 208 110 33 20 0.658 0.577 0.523 87 86 85 - * * 0.586 0.0679485099174368 sp|O43707|ACTN4_HUMAN 100.00 0.0 gi|2804273|dbj|BAA24447.1| alpha actinin 4 [Homo sapiens] 100.00 0.0 sp|O43707|ACTN4_HUMAN Alpha-actinin-4 OS=Homo sapiens GN=ACTN4 PE=1 SV=2 100.00 0.0 H2QG89 H2QG89_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000130402 PE=4 SV=1 SPAC15A10.08 259 1e-68 COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) Z Cytoskeleton ; K05699|1|0.0|1859|ptr:456010|actinin alpha GO:0030168//platelet activation;GO:0042981//regulation of apoptotic process;GO:0051017//actin filament bundle assembly;GO:0051272//positive regulation of cellular component movement;GO:0048549//positive regulation of pinocytosis;GO:0015031//protein transport;GO:0032417//positive regulation of sodium:hydrogen antiporter activity;GO:0001666//response to hypoxia;GO:0002576//platelet degranulation;GO:0051271//negative regulation of cellular component movement GO:0005178//integrin binding;GO:0047485//protein N-terminus binding;GO:0005509//calcium ion binding;GO:0051015//actin filament binding;GO:0001882//nucleoside binding;GO:0042803//protein homodimerization activity GO:0030863//cortical cytoskeleton;GO:0031143//pseudopodium;GO:0031093//platelet alpha granule lumen;GO:0005576//extracellular region;GO:0005829//cytosol;GO:0043234//protein complex;GO:0001725//stress fiber;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0030529//ribonucleoprotein complex 70 sp|Q5VTE0|EF1A3_HUMAN Putative elongation factor 1-alpha-like 3 OS=Homo sapiens GN=EEF1A1P5 PE=5 SV=1 65401 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFKVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHMAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK 499 16.5 11 33 33 6 6 0.569 0.397 0.515 22 22 21 - * * 0.493666666666667 0.0879621130563229 sp|Q5VTE0|EF1A3_HUMAN 100.00 0.0 gi|74746925|sp|Q5VTE0.1|EF1A3_HUMAN RecName: Full=Putative elongation factor 1-alpha-like 3; Short=EF-1-alpha-like 3; AltName: Full=Eukaryotic elongation factor 1 A-like 3; Short=eEF1A-like 3; AltName: Full=Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5 100.00 0.0 sp|Q5VTE0|EF1A3_HUMAN Putative elongation factor 1-alpha-like 3 OS=Homo sapiens GN=EEF1A1P5 PE=5 SV=1 99.57 0.0 Q0PY11 Q0PY11_PIG Elongation factor 1-alpha OS=Sus scrofa GN=EEF1A PE=2 SV=1 SPCC794.09c 774 0.0 COG5256 Translation elongation factor EF-1alpha (GTPase) J Translation, ribosomal structure and biogenesis ; K03231|1|0.0|900|ssc:574059|elongation factor 1-alpha GO:0006355//regulation of transcription, DNA-dependent;GO:0006414//translational elongation;GO:0006184//GTP catabolic process GO:0019901//protein kinase binding;GO:0003746//translation elongation factor activity;GO:0005525//GTP binding;GO:0003924//GTPase activity GO:0005829//cytosol;GO:0005853//eukaryotic translation elongation factor 1 complex;GO:0005634//nucleus 71 tr|Q6FHL9|Q6FHL9_HUMAN PEA15 protein OS=Homo sapiens GN=PEA15 PE=2 SV=1 19375 MVEYGTLLQDLTNNITLEDLEQLKSACKEDIPSEKSEEITTGSAWFSFLESHNKLDKDNLSYIEHIFEISRRPDLLTMVVDYRTRVLKISEEDELDTKLTRIPSAKKYKDIIRQPSEEEIIKLAPPPKKA 285 23.8 1 14 14 2 2 0.706 0.784 0.546 12 13 13 * * * 0.678666666666667 0.121331501817679 tr|Q6FHL9|Q6FHL9_HUMAN 100.00 2e-66 gi|332811039|ref|XP_003308618.1| PREDICTED: astrocytic phosphoprotein PEA-15, partial [Pan troglodytes] 99.23 1e-69 sp|Q9Z297|PEA15_CRIGR Astrocytic phosphoprotein PEA-15 OS=Cricetulus griseus GN=PEA15 PE=1 SV=1 100.00 3e-57 F7DQD4 F7DQD4_MACMU Uncharacterized protein (Fragment) OS=Macaca mulatta GN=Mmu.4628 PE=4 SV=1 - - - - - - - - GO:0035556//intracellular signal transduction;GO:0046325//negative regulation of glucose import;GO:0043278//response to morphine GO:0005080//protein kinase C binding GO:0005875//microtubule associated complex;GO:0005737//cytoplasm 72 tr|J3KMX3|J3KMX3_HUMAN Alpha-fetoprotein OS=Homo sapiens GN=AFP PE=1 SV=1 85062 MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATYKEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEGRHNCFLAHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILLWAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTKLSQKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKITECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSRRHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADIIIGHLCIRHEMTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQAQGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGKRRQNESFIRCELFSLILTDLTLFVN 270 5.5 3 14 14 3 3 0.601 0.588 0.694 10 9 10 * * * 0.627666666666667 0.0578129166651652 tr|J3KMX3|J3KMX3_HUMAN 99.67 0.0 gi|4501989|ref|NP_001125.1| alpha-fetoprotein precursor [Homo sapiens] >gi|120042|sp|P02771.1|FETA_HUMAN RecName: Full=Alpha-fetoprotein; AltName: Full=Alpha-1-fetoprotein; AltName: Full=Alpha-fetoglobulin; Flags: Precursor >gi|178236|gb|AAB58754.1| alpha-fetoprotein [Homo sapiens] >gi|20379787|gb|AAH27881.1| Alpha-fetoprotein [Homo sapiens] >gi|119626086|gb|EAX05681.1| alpha-fetoprotein [Homo sapiens] 99.67 0.0 sp|P02771|FETA_HUMAN Alpha-fetoprotein OS=Homo sapiens GN=AFP PE=1 SV=1 100.00 3e-13 Q8HZ92 Q8HZ92_9PRIM Alpha-fetoprotein (Fragment) OS=Macaca sp. PE=4 SV=1 - - - - - - - K01883|1|8e-93|341|xtr:448227|cysteinyl-tRNA synthetase [EC:6.1.1.16]!K12258|3|3e-27|124|xla:495173|vitamin D-binding protein GO:0006810//transport;GO:0031100//organ regeneration;GO:0001542//ovulation from ovarian follicle;GO:0001889//liver development;GO:0031016//pancreas development;GO:0060395//SMAD protein signal transduction;GO:0042448//progesterone metabolic process;GO:0010033//response to organic substance GO:0046872//metal ion binding GO:0005615//extracellular space;GO:0005737//cytoplasm 73 tr|D6RF35|D6RF35_HUMAN Vitamin D-binding protein OS=Homo sapiens GN=GC PE=1 SV=1 67663 MKRVLVLLLAVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCCSINSPPLYCDSETRVGATQGNDL 764 8.2 1 19 19 2 2 0.825 0.579 0.667 17 16 16 * * * 0.690333333333333 0.124648840080176 tr|D6RF35|D6RF35_HUMAN 100.00 8e-102 gi|297673695|ref|XP_002814890.1| PREDICTED: vitamin D-binding protein-like, partial [Pongo abelii] 99.57 0.0 sp|P02774|VTDB_HUMAN Vitamin D-binding protein OS=Homo sapiens GN=GC PE=1 SV=1 100.00 5e-79 D6RF20 D6RF20_HUMAN Vitamin D-binding protein (Fragment) OS=Homo sapiens GN=GC PE=4 SV=1 - - - - - - - K12258|1|0.0|907|hsa:2638|vitamin D-binding protein GO:0050728//negative regulation of inflammatory response;GO:0043687//post-translational protein modification;GO:0035307//positive regulation of protein dephosphorylation;GO:0009790//embryo development;GO:0007596//blood coagulation;GO:0071356//cellular response to tumor necrosis factor;GO:0046512//sphingosine biosynthetic process;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0051180//vitamin transport;GO:0046513//ceramide biosynthetic process;GO:0043407//negative regulation of MAP kinase activity;GO:0042359//vitamin D metabolic process;GO:0008219//cell death;GO:0005975//carbohydrate metabolic process;GO:0032571//response to vitamin K;GO:0023021//termination of signal transduction;GO:0007565//female pregnancy;GO:0032355//response to estradiol stimulus;GO:0032715//negative regulation of interleukin-6 production;GO:0006680//glucosylceramide catabolic process;GO:0007595//lactation;GO:0006644//phospholipid metabolic process;GO:0007040//lysosome organization GO:0005102//receptor binding;GO:0008488//gamma-glutamyl carboxylase activity;GO:0004348//glucosylceramidase activity;GO:0005499//vitamin D binding;GO:0051183//vitamin transporter activity;GO:0043169//cation binding;GO:0003779//actin binding GO:0005829//cytosol;GO:0005615//extracellular space;GO:0030424//axon;GO:0043202//lysosomal lumen;GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral to membrane;GO:0005765//lysosomal membrane;GO:0005789//endoplasmic reticulum membrane 74 sp|Q13162|PRDX4_HUMAN Peroxiredoxin-4 OS=Homo sapiens GN=PRDX4 PE=1 SV=1 >tr|V9HW63|V9HW63_HUMAN Epididymis secretory sperm binding protein Li 97n OS=Homo sapiens GN=HEL-S-97n PE=2 SV=1 35008 MEALPLLAATTPDHGRHRRLLLLPLLLFLLPAGAVQGWETEERPRTREEECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN 193 35.4 - 20 11 7 6 0.940 0.606 0.740 9 9 9 - * * 0.762 0.16808331267559 sp|Q13162|PRDX4_HUMAN 100.00 9e-141 gi|5453549|ref|NP_006397.1| peroxiredoxin-4 precursor [Homo sapiens] >gi|3024727|sp|Q13162.1|PRDX4_HUMAN RecName: Full=Peroxiredoxin-4; AltName: Full=Antioxidant enzyme AOE372; Short=AOE37-2; AltName: Full=Peroxiredoxin IV; Short=Prx-IV; AltName: Full=Thioredoxin peroxidase AO372; AltName: Full=Thioredoxin-dependent peroxide reductase A0372; Flags: Precursor >gi|799381|gb|AAB95175.1| antioxidant enzyme AOE37-2 [Homo sapiens] >gi|13177646|gb|AAH03609.1| Peroxiredoxin 4 [Homo sapiens] >gi|13937985|gb|AAH07107.1| Peroxiredoxin 4 [Homo sapiens] >gi|16876997|gb|AAH16770.1| Peroxiredoxin 4 [Homo sapiens] >gi|49456371|emb|CAG46506.1| PRDX4 [Homo sapiens] >gi|119619402|gb|EAW98996.1| peroxiredoxin 4 [Homo sapiens] 100.00 1e-141 sp|Q13162|PRDX4_HUMAN Peroxiredoxin-4 OS=Homo sapiens GN=PRDX4 PE=1 SV=1 99.63 1e-139 G3RXK5 G3RXK5_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=PRDX4 PE=4 SV=1 SPCC576.03c 249 5e-66 COG0450 Peroxiredoxin O Posttranslational modification, protein turnover, chaperones ; K03386|1|1e-141|502|hsa:10549|peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15] GO:0007252//I-kappaB phosphorylation;GO:0072593//reactive oxygen species metabolic process;GO:0055114//oxidation-reduction process GO:0005515//protein binding;GO:0008379//thioredoxin peroxidase activity GO:0005615//extracellular space;GO:0005739//mitochondrion 75 sp|O00469|PLOD2_HUMAN Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 OS=Homo sapiens GN=PLOD2 PE=1 SV=2 101496 MGGCTVKPQLLLLALVLHPWNPCLGADSEKPSSIPTDKLLVITVATKESDGFHRFMQSAKYFNYTVKVLGQGEEWRGGDGINSIGGGQKVRLMKEVMEHYADQDDLVVMFTECFDVIFAGGPEEVLKKFQKANHKVVFAADGILWPDKRLADKYPVVHIGKRYLNSGGFIGYAPYVNRIVQQWNLQDNDDDQLFYTKVYIDPLKREAINITLDHKCKIFQTLNGAVDEVVLKFENGKARAKNTFYETLPVAINGNGPTKILLNYFGNYVPNSWTQDNGCTLCEFDTVDLSAVDVHPNVSIGVFIEQPTPFLPRFLDILLTLDYPKEALKLFIHNKEVYHEKDIKVFFDKAKHEIKTIKIVGPEENLSQAEARNMGMDFCRQDEKCDYYFSVDADVVLTNPRTLKILIEQNRKIIAPLVTRHGKLWSNFWGALSPDGYYARSEDYVDIVQGNRVGVWNVPYMANVYLIKGKTLRSEMNERNYFVRDKLDPDMALCRNAREMGVFMYISNRHEFGRLLSTANYNTSHYNNDLWQIFENPVDWKEKYINRDYSKIFTENIVEQPCPDVFWFPIFSEKACDELVEEMEHYGKWSGGKHHDSRISGGYENVPTDDIHMKQVDLENVWLHFIREFIAPVTLKVFAGYYTKGFALLNFVVKYSPERQRSLRPHHDASTFTINIALNNVGEDFQGGGCKFLRYNCSIESPRKGWSFMHPGRLTHLHEGLPVKNGTRYIAVSFIDP 219 10.4 - 12 12 7 7 0.602 0.469 0.425 8 8 8 * * * 0.498666666666667 0.0921538568554422 sp|O00469|PLOD2_HUMAN 100.00 0.0 gi|62089344|dbj|BAD93116.1| procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 isoform b variant [Homo sapiens] 100.00 0.0 sp|O00469|PLOD2_HUMAN Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 OS=Homo sapiens GN=PLOD2 PE=1 SV=2 100.00 5e-123 Q96AR9 Q96AR9_HUMAN PLOD2 protein (Fragment) OS=Homo sapiens GN=PLOD2 PE=2 SV=1 - - - - - - - K13645|1|0.0|1460|hsa:5352|procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 [EC:1.14.11.4] GO:0001666//response to hypoxia;GO:0006464//cellular protein modification process;GO:0032870//cellular response to hormone stimulus;GO:0030198//extracellular matrix organization GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0008475//procollagen-lysine 5-dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0005506//iron ion binding GO:0005581//collagen;GO:0030867//rough endoplasmic reticulum membrane 76 tr|Q2TSD0|Q2TSD0_HUMAN Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens PE=2 SV=1 44411 MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISTPSADAPMLVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE 536 21.2 2 28 28 5 5 0.809 0.716 0.708 19 20 18 * * * 0.744333333333333 0.0561456439390745 tr|Q2TSD0|Q2TSD0_HUMAN 100.00 0.0 gi|54303910|gb|AAV33305.1| aging-associated gene 9 protein [Homo sapiens] 99.40 0.0 sp|P04406|G3P_HUMAN Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens GN=GAPDH PE=1 SV=3 100.00 0.0 Q2TSD0 Q2TSD0_HUMAN Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens PE=2 SV=1 SPBC354.12 501 1e-141 COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase G Carbohydrate transport and metabolism ; K00134|1|0.0|688|hsa:2597|glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] GO:0051402//neuron apoptotic process;GO:0055114//oxidation-reduction process;GO:0035606//peptidyl-cysteine S-trans-nitrosylation;GO:0050821//protein stabilization;GO:0000226//microtubule cytoskeleton organization;GO:0006096//glycolysis;GO:0006094//gluconeogenesis;GO:0044281//small molecule metabolic process GO:0051287//NAD binding;GO:0008017//microtubule binding;GO:0035605//peptidyl-cysteine S-nitrosylase activity;GO:0004365//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661//NADP binding GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0005811//lipid particle;GO:0016020//membrane;GO:0005634//nucleus 77 sp|P27348|1433T_HUMAN 14-3-3 protein theta OS=Homo sapiens GN=YWHAQ PE=1 SV=1 34116 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN 445 24.9 - 31 13 5 3 0.737 0.487 0.582 11 11 11 * * * 0.602 0.12619429464124 sp|P27348|1433T_HUMAN 100.00 1e-131 gi|5803227|ref|NP_006817.1| 14-3-3 protein theta [Homo sapiens] >gi|118151330|ref|NP_001071595.1| 14-3-3 protein theta [Bos taurus] >gi|112690|sp|P27348.1|1433T_HUMAN RecName: Full=14-3-3 protein theta; AltName: Full=14-3-3 protein T-cell; AltName: Full=14-3-3 protein tau; AltName: Full=Protein HS1 >gi|68565141|sp|Q5RFJ2.2|1433T_PONAB RecName: Full=14-3-3 protein theta >gi|82592596|sp|Q3SZI4.1|1433T_BOVIN RecName: Full=14-3-3 protein theta >gi|23222|emb|CAA39840.1| 14.3.3 protein [Homo sapiens] >gi|32464|emb|CAA40622.1| HS1 [Homo sapiens] >gi|34785143|gb|AAH56867.1| Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide [Homo sapiens] >gi|55930909|gb|AAH50601.1| Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide [Homo sapiens] >gi|62205258|gb|AAH93019.1| Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide [Homo sapiens] >gi|74354028|gb|AAI02841.1| Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide [Bos taurus] >gi|119621382|gb|EAX00977.1| tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide, isoform CRA_a [Homo sapiens] >gi|119621384|gb|EAX00979.1| tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide, isoform CRA_a [Homo sapiens] >gi|152941256|gb|ABS45065.1| tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide [Bos taurus] >gi|154426168|gb|AAI51415.1| Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide [Bos taurus] >gi|296482326|tpg|DAA24441.1| TPA: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide [Bos taurus] >gi|351704793|gb|EHB07712.1| 14-3-3 protein theta [Heterocephalus glaber] >gi|444731699|gb|ELW72048.1| 14-3-3 protein theta [Tupaia chinensis] 100.00 1e-132 sp|P27348|1433T_HUMAN 14-3-3 protein theta OS=Homo sapiens GN=YWHAQ PE=1 SV=1 100.00 4e-131 G1RT54 G1RT54_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=ENSG00000134308 PE=3 SV=1 SPAC8E11.02c 306 3e-83 COG5040 14-3-3 family protein T Signal transduction mechanisms ; K06630|1|4e-134|477|ptr:470302|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein GO:0055114//oxidation-reduction process;GO:0007264//small GTPase mediated signal transduction;GO:0006605//protein targeting;GO:0045892//negative regulation of transcription, DNA-dependent GO:0047485//protein N-terminus binding;GO:0004497//monooxygenase activity;GO:0071889//14-3-3 protein binding;GO:0019904//protein domain specific binding GO:0043234//protein complex;GO:0005730//nucleolus;GO:0005813//centrosome 78 sp|P35754|GLRX1_HUMAN Glutaredoxin-1 OS=Homo sapiens GN=GLRX PE=1 SV=2 >tr|A0A024RAM2|A0A024RAM2_HUMAN Glutaredoxin (Thioltransferase), isoform CRA_c OS=Homo sapiens GN=GLRX PE=4 SV=1 14183 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ 132 23.6 - 10 10 3 3 0.629 0.596 0.383 6 6 6 - * * 0.536 0.133525278505607 sp|P35754|GLRX1_HUMAN 100.00 2e-55 gi|4504025|ref|NP_002055.1| glutaredoxin-1 [Homo sapiens] >gi|169646776|ref|NP_001112362.1| glutaredoxin-1 [Homo sapiens] >gi|304766562|ref|NP_001182153.1| glutaredoxin-1 [Pan troglodytes] >gi|343887374|ref|NP_001230587.1| glutaredoxin-1 [Homo sapiens] >gi|343887376|ref|NP_001230588.1| glutaredoxin-1 [Homo sapiens] >gi|1346143|sp|P35754.2|GLRX1_HUMAN RecName: Full=Glutaredoxin-1; AltName: Full=Thioltransferase-1; Short=TTase-1 >gi|157831548|pdb|1JHB|A Chain A, Human Glutaredoxin In Fully Reduced Form, Nmr, 20 Structures >gi|5442446|gb|AAD43353.1|AF162769_1 thioltransferase [Homo sapiens] >gi|531405|emb|CAA54094.1| glutaredoxin [Homo sapiens] >gi|3603310|gb|AAC35798.1| glutaredoxin [Homo sapiens] >gi|4063519|gb|AAC98318.1| glutaredoxin [Homo sapiens] >gi|13529038|gb|AAH05304.1| GLRX protein [Homo sapiens] >gi|15012115|gb|AAH10965.1| GLRX protein [Homo sapiens] >gi|30582217|gb|AAP35335.1| glutaredoxin (thioltransferase) [Homo sapiens] >gi|47496571|emb|CAG29308.1| GLRX [Homo sapiens] >gi|49457326|emb|CAG46962.1| GLRX [Homo sapiens] >gi|63055291|gb|AAY29058.1| glutaredoxin (thioltransferase) [Homo sapiens] >gi|76779257|gb|AAI06076.1| GLRX protein [Homo sapiens] >gi|119616462|gb|EAW96056.1| glutaredoxin (thioltransferase), isoform CRA_c [Homo sapiens] >gi|119616463|gb|EAW96057.1| glutaredoxin (thioltransferase), isoform CRA_c [Homo sapiens] >gi|1093459|prf||2104198A glutaredoxin >gi|1584612|prf||2123294A thioltransferase 100.00 3e-56 sp|P35754|GLRX1_HUMAN Glutaredoxin-1 OS=Homo sapiens GN=GLRX PE=1 SV=2 100.00 1e-54 H2PG48 H2PG48_PONAB Uncharacterized protein OS=Pongo abelii GN=LOC100449892 PE=4 SV=1 SPAC4F10.20 73.2 1e-13 COG0695 Glutaredoxin and related proteins O Posttranslational modification, protein turnover, chaperones ; K03676|1|3e-56|216|pon:100436888|glutaredoxin 3 GO:0045454//cell redox homeostasis;GO:0006810//transport;GO:0015949//nucleobase-containing small molecule interconversion;GO:0022900//electron transport chain GO:0009055//electron carrier activity;GO:0047485//protein N-terminus binding;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0019153//protein-disulfide reductase (glutathione) activity;GO:0015035//protein disulfide oxidoreductase activity GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion 79 tr|B3KRV6|B3KRV6_HUMAN cDNA FLJ34961 fis, clone NTONG2003839, highly similar to CONNECTIVE TISSUE GROWTH FACTOR OS=Homo sapiens PE=2 SV=1 42581 MTAASMGPVRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVRDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKIPKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA 592 24.9 2 31 31 6 6 0.406 0.484 0.379 20 20 19 * - * 0.423 0.0545252235208623 tr|B3KRV6|B3KRV6_HUMAN 100.00 2e-175 gi|193787312|dbj|BAG52518.1| unnamed protein product [Homo sapiens] 98.31 3e-168 sp|P29279|CTGF_HUMAN Connective tissue growth factor OS=Homo sapiens GN=CTGF PE=1 SV=2 100.00 8e-175 B3KRV6 B3KRV6_HUMAN cDNA FLJ34961 fis, clone NTONG2003839, highly similar to CONNECTIVE TISSUE GROWTH FACTOR OS=Homo sapiens PE=2 SV=1 - - - - - - - K06827|1|6e-169|593|hsa:1490|connective tissue growth factor GO:0008284//positive regulation of cell proliferation;GO:0043434//response to peptide hormone stimulus;GO:0007160//cell-matrix adhesion;GO:0060401//cytosolic calcium ion transport;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0009749//response to glucose stimulus;GO:0001558//regulation of cell growth;GO:0070278//extracellular matrix constituent secretion;GO:0014070//response to organic cyclic compound;GO:0010260//organ senescence;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0072593//reactive oxygen species metabolic process;GO:0001503//ossification;GO:0016477//cell migration;GO:0008544//epidermis development;GO:0043200//response to amino acid stimulus;GO:0001934//positive regulation of protein phosphorylation;GO:0045597//positive regulation of cell differentiation;GO:0044255//cellular lipid metabolic process;GO:0050867//positive regulation of cell activation;GO:0044281//small molecule metabolic process;GO:0051496//positive regulation of stress fiber assembly;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006260//DNA replication;GO:0010942//positive regulation of cell death;GO:0070318//positive regulation of G0 to G1 transition;GO:0001525//angiogenesis;GO:0046330//positive regulation of JNK cascade;GO:0007229//integrin-mediated signaling pathway;GO:0010628//positive regulation of gene expression;GO:0051385//response to mineralocorticoid stimulus;GO:0032355//response to estradiol stimulus;GO:0060452//positive regulation of cardiac muscle contraction;GO:0070542//response to fatty acid;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0001502//cartilage condensation;GO:0009611//response to wounding;GO:0032967//positive regulation of collagen biosynthetic process;GO:0030324//lung development;GO:0034059//response to anoxia GO:0008201//heparin binding;GO:0005178//integrin binding;GO:0008083//growth factor activity;GO:0001968//fibronectin binding;GO:0005520//insulin-like growth factor binding GO:0005829//cytosol;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix;GO:0048471//perinuclear region of cytoplasm;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005938//cell cortex 80 sp|P13521|SCG2_HUMAN Secretogranin-2 OS=Homo sapiens GN=SCG2 PE=1 SV=2 83978 MAEAKTHWLGAALSLIPLIFLISGAEAASFQRNQLLQKEPDLRLENVQKFPSPEMIRALEYIENLRQQAHKEESSPDYNPYQGVSVPLQQKENGDESHLPERDSLSEEDWMRIILEALRQAENEPQSAPKENKPYALNSEKNFPMDMSDDYETQQWPERKLKHMQFPPMYEENSRDNPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPNNQKRERMDEEQKLYTDDEDDIYKANNIAYEDVVGGEDWNPVEEKIESQTQEEVRDSKENIEKNEQINDEMKRSGQLGIQEEDLRKESKDQLSDDVSKVIAYLKRLVNAAGSGRLQNGQNGERATRLFEKPLDSQSIYQLIEISRNLQIPPEDLIEMLKTGEKPNGSVEPERELDLPVDLDDISEADLDHPDLFQNRMLSKSGYPKTPGRAGTEALPDGLSVEDILNLLGMESAANQKTSYFPNPYNQEKVLPRLPYGAGRSRSNQLPKAAWIPHVENRQMAYENLNDKDQELGEYLARMLVKYPEIINSNQVKRVPGQGSSEDDLQEEEQIEQAIKEHLNQGSSQETDKLAPVSKRFPVGPPKNDDTPNRQYWDEDLLMKVLEYLNQEKAEKGREHIAKRAMENM 138 8.3 - 10 10 5 5 0.473 0.326 0.347 8 8 8 * - * 0.382 0.0795047168412038 sp|P13521|SCG2_HUMAN 100.00 0.0 gi|68160947|ref|NP_003460.2| secretogranin-2 precursor [Homo sapiens] >gi|143811457|sp|P13521.2|SCG2_HUMAN RecName: Full=Secretogranin-2; AltName: Full=Chromogranin-C; AltName: Full=Secretogranin II; Short=SgII; Contains: RecName: Full=Secretoneurin; Short=SN; Flags: Precursor >gi|119591217|gb|EAW70811.1| secretogranin II (chromogranin C) [Homo sapiens] 100.00 0.0 sp|P13521|SCG2_HUMAN Secretogranin-2 OS=Homo sapiens GN=SCG2 PE=1 SV=2 100.00 9e-77 C9JQI2 C9JQI2_HUMAN Secretoneurin (Fragment) OS=Homo sapiens GN=SCG2 PE=4 SV=1 - - - - - - - - GO:0032925//regulation of activin receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0048704//embryonic skeletal system morphogenesis;GO:0006954//inflammatory response;GO:0046329//negative regulation of JNK cascade;GO:0030097//hemopoiesis;GO:0006281//DNA repair;GO:0032092//positive regulation of protein binding;GO:0045669//positive regulation of osteoblast differentiation;GO:0010332//response to gamma radiation;GO:0001776//leukocyte homeostasis;GO:0007420//brain development;GO:0051974//negative regulation of telomerase activity;GO:0034968//histone lysine methylation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045668//negative regulation of osteoblast differentiation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0051781//positive regulation of cell division;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0060135//maternal process involved in female pregnancy;GO:0009411//response to UV;GO:0043542//endothelial cell migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050930//induction of positive chemotaxis;GO:0001937//negative regulation of endothelial cell proliferation;GO:0002051//osteoblast fate commitment;GO:0031062//positive regulation of histone methylation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0046621//negative regulation of organ growth;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007050//cell cycle arrest;GO:0001525//angiogenesis;GO:0006338//chromatin remodeling;GO:0060021//palate development;GO:0043066//negative regulation of apoptotic process;GO:0048245//eosinophil chemotaxis;GO:0002076//osteoblast development;GO:0009306//protein secretion;GO:0001938//positive regulation of endothelial cell proliferation GO:0047485//protein N-terminus binding;GO:0003690//double-stranded DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0005125//cytokine activity;GO:0000403//Y-form DNA binding;GO:0003682//chromatin binding;GO:0000400//four-way junction DNA binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0030674//protein binding, bridging;GO:0042056//chemoattractant activity;GO:0070412//R-SMAD binding GO:0016363//nuclear matrix;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0032154//cleavage furrow;GO:0030141//secretory granule;GO:0035097//histone methyltransferase complex;GO:0000785//chromatin;GO:0005730//nucleolus 81 tr|Q6FHN2|Q6FHN2_HUMAN CTSK protein (Fragment) OS=Homo sapiens GN=CTSK PE=2 SV=1 46187 MWGLKVLLLPVVSLALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 358 24.0 1 10 10 5 5 0.712 0.412 0.533 10 10 10 - * * 0.552333333333333 0.150931551815163 tr|Q6FHN2|Q6FHN2_HUMAN 100.00 3e-123 gi|315364648|pdb|3OVZ|A Chain A, Cathepsin K In Complex With A Covalent Inhibitor With A Ketoamide Warhead 99.70 0.0 sp|P43235|CATK_HUMAN Cathepsin K OS=Homo sapiens GN=CTSK PE=1 SV=1 100.00 0.0 Q6FHN2 Q6FHN2_HUMAN CTSK protein (Fragment) OS=Homo sapiens GN=CTSK PE=2 SV=1 AF1946_2 83.2 7e-16 COG4870 Cysteine protease O Posttranslational modification, protein turnover, chaperones ; K01371|1|0.0|683|hsa:1513|cathepsin K [EC:3.4.22.38] GO:0045087//innate immune response;GO:0001957//intramembranous ossification;GO:0045453//bone resorption;GO:0006508//proteolysis GO:0004197//cysteine-type endopeptidase activity GO:0005615//extracellular space;GO:0036021//endolysosome lumen 82 tr|Q6ZME7|Q6ZME7_HUMAN cDNA FLJ23972 fis, clone HEP18230, highly similar to 65 kDa FK506-binding protein (EC 5.2.1.8) OS=Homo sapiens PE=2 SV=1 64920 MFPAGPPSHSLLRLPLLQLLLLVVQAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGLAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDAVQLEALELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGARGVPGSAVLLFEVELVSREDGLPTGYLFVWHKDPPANLFEDMDLNKDGEVPPEEFSTFIKAQVSEGKGRPHAWAGP 550 15.1 2 22 22 7 7 0.785 0.827 0.980 16 16 16 * * - 0.864 0.102630404851584 tr|Q6ZME7|Q6ZME7_HUMAN 100.00 1e-123 gi|6453607|emb|CAB61418.1| hypothetical protein [Homo sapiens] 99.81 0.0 sp|Q96AY3|FKB10_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP10 OS=Homo sapiens GN=FKBP10 PE=1 SV=1 100.00 0.0 Q6ZME7 Q6ZME7_HUMAN cDNA FLJ23972 fis, clone HEP18230, highly similar to 65 kDa FK506-binding protein (EC 5.2.1.8) OS=Homo sapiens PE=2 SV=1 DR1839 100 7e-21 COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 O Posttranslational modification, protein turnover, chaperones ; K09575|1|0.0|1042|hsa:60681|FK506-binding protein 9/10 [EC:5.2.1.8] GO:0006457//protein folding;GO:0000413//protein peptidyl-prolyl isomerization GO:0005528//FK506 binding;GO:0005509//calcium ion binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane 83 sp|P12814|ACTN1_HUMAN Alpha-actinin-1 OS=Homo sapiens GN=ACTN1 PE=1 SV=2 >tr|A0A024R694|A0A024R694_HUMAN Actinin, alpha 1, isoform CRA_a OS=Homo sapiens GN=ACTN1 PE=4 SV=1 120294 MDHYDSQQTNDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQVEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITMDELRRELPPDQAEYCIARMAPYTGPDSVPGALDYMSFSTALYGESDL 5560 44.8 - 277 187 34 22 0.652 0.527 0.514 143 147 144 * * * 0.564333333333333 0.0761993000842746 sp|P12814|ACTN1_HUMAN 100.00 0.0 gi|4501891|ref|NP_001093.1| alpha-actinin-1 isoform b [Homo sapiens] >gi|46397817|sp|P12814.2|ACTN1_HUMAN RecName: Full=Alpha-actinin-1; AltName: Full=Alpha-actinin cytoskeletal isoform; AltName: Full=F-actin cross-linking protein; AltName: Full=Non-muscle alpha-actinin-1 >gi|178052|gb|AAA51582.1| alpha-actinin [Homo sapiens] >gi|13097756|gb|AAH03576.1| Actinin, alpha 1 [Homo sapiens] >gi|16041771|gb|AAH15766.1| Actinin, alpha 1 [Homo sapiens] >gi|30583253|gb|AAP35871.1| actinin, alpha 1 [Homo sapiens] >gi|119601377|gb|EAW80971.1| actinin, alpha 1, isoform CRA_a [Homo sapiens] >gi|119601382|gb|EAW80976.1| actinin, alpha 1, isoform CRA_a [Homo sapiens] 100.00 0.0 sp|P12814|ACTN1_HUMAN Alpha-actinin-1 OS=Homo sapiens GN=ACTN1 PE=1 SV=2 100.00 0.0 H9F1Z8 H9F1Z8_MACMU Alpha-actinin-1 isoform c (Fragment) OS=Macaca mulatta GN=ACTN1 PE=2 SV=1 SPAC15A10.08 271 5e-72 COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) Z Cytoskeleton ; K05699|1|0.0|1863|hsa:87|actinin alpha GO:0043462//regulation of ATPase activity;GO:0030168//platelet activation;GO:0046928//regulation of neurotransmitter secretion;GO:0042981//regulation of apoptotic process;GO:0051017//actin filament bundle assembly;GO:0048041//focal adhesion assembly;GO:0002576//platelet degranulation;GO:0051271//negative regulation of cellular component movement GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0019904//protein domain specific binding;GO:0005523//tropomyosin binding;GO:0043495//protein anchor;GO:0051015//actin filament binding;GO:0017166//vinculin binding;GO:0044325//ion channel binding GO:0005925//focal adhesion;GO:0031143//pseudopodium;GO:0012506//vesicle membrane;GO:0043197//dendritic spine;GO:0031093//platelet alpha granule lumen;GO:0005576//extracellular region;GO:0005829//cytosol;GO:0001726//ruffle;GO:0001725//stress fiber;GO:0030018//Z disc;GO:0005916//fascia adherens;GO:0030864//cortical actin cytoskeleton;GO:0005634//nucleus 84 tr|H0YL52|H0YL52_HUMAN Tropomyosin alpha-1 chain (Fragment) OS=Homo sapiens GN=TPM1 PE=1 SV=1 40873 XRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 1916 21.1 2 121 15 7 1 0.503 0.393 0.350 10 10 10 * * * 0.415333333333333 0.0789071183945614 tr|H0YL52|H0YL52_HUMAN 100.00 6e-109 gi|339956|gb|AAA61226.1| skeletal muscle tropomyosin, partial [Homo sapiens] 99.60 3e-109 sp|P09493|TPM1_HUMAN Tropomyosin alpha-1 chain OS=Homo sapiens GN=TPM1 PE=1 SV=2 100.00 8e-82 H0YNC7 H0YNC7_HUMAN Tropomyosin alpha-1 chain (Fragment) OS=Homo sapiens GN=TPM1 PE=3 SV=1 - - - - - - - K10373|1|8e-109|393|mmu:22003|tropomyosin 1 GO:0034614//cellular response to reactive oxygen species;GO:0001701//in utero embryonic development;GO:0032781//positive regulation of ATPase activity;GO:0060048//cardiac muscle contraction;GO:0030336//negative regulation of cell migration;GO:0045785//positive regulation of cell adhesion;GO:0051693//actin filament capping;GO:0006937//regulation of muscle contraction;GO:0030049//muscle filament sliding;GO:0045214//sarcomere organization;GO:0031529//ruffle organization;GO:0042060//wound healing;GO:0051496//positive regulation of stress fiber assembly;GO:0003065//positive regulation of heart rate by epinephrine;GO:0055010//ventricular cardiac muscle tissue morphogenesis GO:0042803//protein homodimerization activity;GO:0047485//protein N-terminus binding;GO:0005200//structural constituent of cytoskeleton;GO:0051015//actin filament binding;GO:0008307//structural constituent of muscle GO:0032059//bleb;GO:0005862//muscle thin filament tropomyosin;GO:0005829//cytosol;GO:0031941//filamentous actin;GO:0001725//stress fiber;GO:0032587//ruffle membrane 85 sp|Q01995|TAGL_HUMAN Transgelin OS=Homo sapiens GN=TAGLN PE=1 SV=4 >tr|Q5U0D2|Q5U0D2_HUMAN Transgelin OS=Homo sapiens GN=TAGLN PE=2 SV=1 28129 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS 2447 56.7 - 159 159 10 10 0.408 0.369 0.338 98 109 102 * * - 0.371666666666667 0.0350761077278157 sp|Q01995|TAGL_HUMAN 100.00 6e-49 gi|62088690|dbj|BAD92792.1| transgelin variant [Homo sapiens] 100.00 1e-116 sp|Q01995|TAGL_HUMAN Transgelin OS=Homo sapiens GN=TAGLN PE=1 SV=4 100.00 4e-115 G3REJ2 G3REJ2_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=TAGLN PE=4 SV=1 YOR367w 70.5 2e-12 COG5199 Calponin Z Cytoskeleton ; K05730|1|3e-07|55.1|dre:559145|vav oncogene GO:0007517//muscle organ development GO:0003779//actin binding GO:0005737//cytoplasm 86 tr|Q59GM9|Q59GM9_HUMAN Alpha-1,4 glucan phosphorylase (Fragment) OS=Homo sapiens PE=2 SV=1 116848 IPAFACAAAFLLHLFSSASAGAMAKPLTDSEKRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVASTLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLANTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNIPRD 137 9.9 1 10 7 8 6 0.802 0.543 0.651 4 4 3 - * * 0.665333333333333 0.130093556079205 tr|Q59GM9|Q59GM9_HUMAN 100.00 0.0 gi|62087740|dbj|BAD92317.1| brain glycogen phosphorylase variant [Homo sapiens] 99.76 0.0 sp|P11216|PYGB_HUMAN Glycogen phosphorylase, brain form OS=Homo sapiens GN=PYGB PE=1 SV=5 100.00 5e-11 G7PH60 G7PH60_MACFA Phosphorylase OS=Macaca fascicularis GN=EGM_02405 PE=3 SV=1 CPn0307 872 0.0 COG0058 Glucan phosphorylase G Carbohydrate transport and metabolism ; K00688|1|0.0|1692|hsa:5834|starch phosphorylase [EC:2.4.1.1] GO:0005980//glycogen catabolic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process GO:0008184//glycogen phosphorylase activity;GO:0030170//pyridoxal phosphate binding;GO:0030246//carbohydrate binding;GO:0008144//drug binding;GO:0042803//protein homodimerization activity GO:0005737//cytoplasm;GO:0030424//axon 87 sp|P27816|MAP4_HUMAN Microtubule-associated protein 4 OS=Homo sapiens GN=MAP4 PE=1 SV=3 156122 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNSESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI 340 6.2 1 16 16 5 5 0.829 0.773 0.707 14 14 14 * * * 0.769666666666667 0.0610682678101593 sp|P27816|MAP4_HUMAN 100.00 0.0 gi|47519639|ref|NP_002366.2| microtubule-associated protein 4 isoform 1 [Homo sapiens] >gi|269849673|sp|P27816.3|MAP4_HUMAN RecName: Full=Microtubule-associated protein 4; Short=MAP-4 100.00 0.0 sp|P27816|MAP4_HUMAN Microtubule-associated protein 4 OS=Homo sapiens GN=MAP4 PE=1 SV=3 100.00 0.0 Q05D06 Q05D06_HUMAN MAP4 protein (Fragment) OS=Homo sapiens GN=MAP4 PE=2 SV=1 - - - - - - - K10431|1|0.0|1988|ptr:460339|microtubule-associated protein 4 - GO:0015631//tubulin binding;GO:0005198//structural molecule activity GO:0005875//microtubule associated complex;GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0005886//plasma membrane 88 tr|Q6P6D7|Q6P6D7_HUMAN Phosphoglycerate mutase 1 (Brain) OS=Homo sapiens GN=PGAM1 PE=2 SV=1 34696 MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLLVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKAKK 816 31.1 2 29 29 6 6 0.863 0.796 0.640 27 27 27 * * * 0.766333333333333 0.114421734532095 tr|Q6P6D7|Q6P6D7_HUMAN 100.00 2e-140 gi|38566176|gb|AAH62302.1| Phosphoglycerate mutase 1 (brain) [Homo sapiens] 99.61 2e-140 sp|P18669|PGAM1_HUMAN Phosphoglycerate mutase 1 OS=Homo sapiens GN=PGAM1 PE=1 SV=2 100.00 6e-140 Q6P6D7 Q6P6D7_HUMAN Phosphoglycerate mutase OS=Homo sapiens GN=PGAM1 PE=2 SV=1 gpmA 298 6e-81 COG0588 Phosphoglycerate mutase 1 G Carbohydrate transport and metabolism ; K01834|1|1e-140|498|ssc:100154776|2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.1] GO:0045730//respiratory burst;GO:0043456//regulation of pentose-phosphate shunt;GO:0006094//gluconeogenesis;GO:0006110//regulation of glycolysis GO:0046538//2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity;GO:0019901//protein kinase binding;GO:0004082//bisphosphoglycerate mutase activity;GO:0004083//bisphosphoglycerate 2-phosphatase activity GO:0005829//cytosol;GO:0005634//nucleus 89 sp|P04080|CYTB_HUMAN Cystatin-B OS=Homo sapiens GN=CSTB PE=1 SV=2 >tr|Q76LA1|Q76LA1_HUMAN CSTB protein OS=Homo sapiens GN=CSTB PE=2 SV=1 14232 MMCGAPSATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF 720 33.7 - 23 23 3 3 0.814 0.644 0.677 21 21 21 * * * 0.711666666666667 0.0901461775858152 sp|P04080|CYTB_HUMAN 100.00 4e-52 gi|4503117|ref|NP_000091.1| cystatin-B [Homo sapiens] >gi|1706278|sp|P04080.2|CYTB_HUMAN RecName: Full=Cystatin-B; AltName: Full=CPI-B; AltName: Full=Liver thiol proteinase inhibitor; AltName: Full=Stefin-B >gi|45476793|sp|P60575.1|CYTB_PANPA RecName: Full=Cystatin-B; AltName: Full=Stefin-B >gi|45476794|sp|P60576.1|CYTB_PONPY RecName: Full=Cystatin-B; AltName: Full=Stefin-B >gi|52000705|sp|Q76LA0.1|CYTB_GORGO RecName: Full=Cystatin-B; AltName: Full=Stefin-B >gi|7263012|gb|AAF44059.1|AF208234_1 cystatin B [Homo sapiens] >gi|291927|gb|AAA35727.1| cystatin B [Homo sapiens] >gi|1235678|gb|AAA99014.1| cystatin B [Homo sapiens] >gi|7768760|dbj|BAA95541.1| cystatin B (liver thiol proteinase inhibitor) [Homo sapiens] >gi|13097210|gb|AAH03370.1| Cystatin B (stefin B) [Homo sapiens] >gi|14714769|gb|AAH10532.1| Cystatin B (stefin B) [Homo sapiens] >gi|23496466|dbj|BAC20304.1| cystatin B [Homo sapiens] >gi|23496470|dbj|BAC20306.1| cystatin B [Pan paniscus] >gi|23496472|dbj|BAC20307.1| cystatin B [Gorilla gorilla] >gi|23496474|dbj|BAC20308.1| cystatin B [Pongo pygmaeus] >gi|30582919|gb|AAP35689.1| cystatin B (stefin B) [Homo sapiens] >gi|49457292|emb|CAG46945.1| CSTB [Homo sapiens] >gi|119629878|gb|EAX09473.1| cystatin B (stefin B), isoform CRA_a [Homo sapiens] >gi|119629879|gb|EAX09474.1| cystatin B (stefin B), isoform CRA_a [Homo sapiens] 100.00 5e-53 sp|Q76LA0|CYTB_GORGO Cystatin-B OS=Gorilla gorilla gorilla GN=CSTB PE=3 SV=1 100.00 2e-51 Q76LA1 Q76LA1_HUMAN CSTB protein OS=Homo sapiens GN=CSTB PE=2 SV=1 - - - - - - - K13907|1|4e-53|206|pon:100433135|cystatin-A/B GO:0010951//negative regulation of endopeptidase activity;GO:0042981//regulation of apoptotic process;GO:0008344//adult locomotory behavior GO:0002020//protease binding;GO:0004869//cysteine-type endopeptidase inhibitor activity GO:0005737//cytoplasm;GO:0005730//nucleolus 90 tr|B2RD14|B2RD14_HUMAN Ubiquitin carboxyl-terminal hydrolase OS=Homo sapiens PE=2 SV=1 30338 MQLKPMEINPEMLNKVLYRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPSPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA 477 24.2 1 29 29 5 5 0.445 0.395 0.464 12 13 12 * * * 0.434666666666667 0.0356417358350198 tr|B2RD14|B2RD14_HUMAN 100.00 2e-119 gi|189067502|dbj|BAG37761.1| unnamed protein product [Homo sapiens] 99.10 2e-118 sp|P09936|UCHL1_HUMAN Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Homo sapiens GN=UCHL1 PE=1 SV=2 100.00 6e-119 B2RD14 B2RD14_HUMAN cDNA, FLJ96414, highly similar to Homo sapiens ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1), mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K05611|1|2e-118|424|hsa:7345|ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12] GO:0007412//axon target recognition;GO:0016579//protein deubiquitination;GO:0042755//eating behavior;GO:0043407//negative regulation of MAP kinase activity;GO:0008283//cell proliferation;GO:0048747//muscle fiber development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007628//adult walking behavior;GO:0008219//cell death;GO:0019233//sensory perception of pain;GO:0006950//response to stress;GO:0019896//axon transport of mitochondrion;GO:0050905//neuromuscular process GO:0004197//cysteine-type endopeptidase activity;GO:0016874//ligase activity;GO:0043130//ubiquitin binding;GO:0004221//ubiquitin thiolesterase activity;GO:0008242//omega peptidase activity;GO:0031694//alpha-2A adrenergic receptor binding GO:0005789//endoplasmic reticulum membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0043025//neuronal cell body;GO:0030424//axon;GO:0005886//plasma membrane 91 sp|P21281|VATB2_HUMAN V-type proton ATPase subunit B, brain isoform OS=Homo sapiens GN=ATP6V1B2 PE=1 SV=3 63500 MALRAMRGIVNGAAPELPVPTGGPAVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTVFETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH 257 11.9 - 10 10 4 4 0.575 0.708 0.595 9 9 8 * * * 0.626 0.071714712576988 sp|P21281|VATB2_HUMAN 100.00 0.0 gi|19913428|ref|NP_001684.2| V-type proton ATPase subunit B, brain isoform [Homo sapiens] >gi|12643271|sp|P21281.3|VATB2_HUMAN RecName: Full=V-type proton ATPase subunit B, brain isoform; Short=V-ATPase subunit B 2; AltName: Full=Endomembrane proton pump 58 kDa subunit; AltName: Full=HO57; AltName: Full=Vacuolar proton pump subunit B 2 >gi|13111865|gb|AAH03100.1| ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 [Homo sapiens] >gi|119584162|gb|EAW63758.1| ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2, isoform CRA_a [Homo sapiens] >gi|119584163|gb|EAW63759.1| ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2, isoform CRA_a [Homo sapiens] 100.00 0.0 sp|P21281|VATB2_HUMAN V-type proton ATPase subunit B, brain isoform OS=Homo sapiens GN=ATP6V1B2 PE=1 SV=3 100.00 0.0 G1QJ94 G1QJ94_NOMLE Uncharacterized protein OS=Nomascus leucogenys GN=ATP6V1B2 PE=3 SV=1 YBR127c 795 0.0 COG1156 Archaeal/vacuolar-type H+-ATPase subunit B C Energy production and conversion ; K02147|1|0.0|1055|ptr:464033|V-type H+-transporting ATPase subunit B [EC:3.6.3.14] GO:0033572//transferrin transport;GO:0090382//phagosome maturation;GO:0008286//insulin receptor signaling pathway;GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0007035//vacuolar acidification;GO:0051701//interaction with host;GO:0042777//plasma membrane ATP synthesis coupled proton transport GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0005524//ATP binding GO:0005773//vacuole;GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0005902//microvillus;GO:0042470//melanosome;GO:0016021//integral to membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0012505//endomembrane system;GO:0005886//plasma membrane 92 sp|Q14315|FLNC_HUMAN Filamin-C OS=Homo sapiens GN=FLNC PE=1 SV=3 341775 MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITNFNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIERSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPVVPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIPNGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKAKLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTPAPFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGVEPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDVVDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDEIPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGDASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTYCPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPAVFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVPQEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVPVASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELDSDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTTGVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGPQHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP 1614 14.2 - 88 55 32 26 0.509 0.541 0.413 34 37 35 - * * 0.487666666666667 0.0666133119829163 sp|Q14315|FLNC_HUMAN 100.00 0.0 gi|116805322|ref|NP_001449.3| filamin-C isoform a [Homo sapiens] >gi|254763419|sp|Q14315.3|FLNC_HUMAN RecName: Full=Filamin-C; Short=FLN-C; Short=FLNc; AltName: Full=ABP-280-like protein; AltName: Full=ABP-L; AltName: Full=Actin-binding-like protein; AltName: Full=Filamin-2; AltName: Full=Gamma-filamin >gi|7677526|gb|AAF67190.1|AF252549_1 gamma-filamin [Homo sapiens] >gi|119604097|gb|EAW83691.1| filamin C, gamma (actin binding protein 280), isoform CRA_c [Homo sapiens] >gi|190192200|dbj|BAG48314.1| filamin C [Homo sapiens] 100.00 0.0 sp|Q14315|FLNC_HUMAN Filamin-C OS=Homo sapiens GN=FLNC PE=1 SV=3 100.00 0.0 Q59H94 Q59H94_HUMAN Gamma filamin variant (Fragment) OS=Homo sapiens PE=1 SV=1 ECU09g0290 143 5e-33 COG5069 Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) Z Cytoskeleton ; K04437|1|0.0|5312|ssc:100518997|filamin GO:0034329//cell junction assembly GO:0003779//actin binding;GO:0030506//ankyrin binding GO:0030018//Z disc;GO:0005856//cytoskeleton;GO:0043034//costamere;GO:0042383//sarcolemma;GO:0005829//cytosol 93 tr|B4DPW5|B4DPW5_HUMAN cDNA FLJ59374, highly similar to Homo sapiens caldesmon 1 (CALD1), transcript variant 2, mRNA OS=Homo sapiens PE=2 SV=1 77818 MDDFERRRELRRQKREVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEGKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGDVSSKRNLWEKQSVDKVTSPTKEPVSKETHAVK 781 16.5 4 47 47 9 9 0.445 0.426 0.324 31 31 30 * - * 0.398333333333333 0.0650717552655016 tr|B4DPW5|B4DPW5_HUMAN 100.00 4e-97 gi|221043146|dbj|BAH13250.1| unnamed protein product [Homo sapiens] 100.00 3e-26 sp|Q05682|CALD1_HUMAN Caldesmon OS=Homo sapiens GN=CALD1 PE=1 SV=3 100.00 1e-96 B7Z6G4 B7Z6G4_HUMAN cDNA FLJ53193, highly similar to Homo sapiens caldesmon 1 (CALD1), transcript variant 5, mRNA OS=Homo sapiens PE=2 SV=1 - - - - - - - K12327|1|3e-98|359|ptr:472523|caldesmon GO:0051017//actin filament bundle assembly;GO:0032092//positive regulation of protein binding;GO:0006928//cellular component movement;GO:0006936//muscle contraction GO:0005516//calmodulin binding;GO:0003779//actin binding;GO:0017022//myosin binding;GO:0005523//tropomyosin binding GO:0005829//cytosol;GO:0030016//myofibril;GO:0043025//neuronal cell body;GO:0005884//actin filament;GO:0014069//postsynaptic density;GO:0030478//actin cap;GO:0005886//plasma membrane 94 tr|A0A0A0MTS2|A0A0A0MTS2_HUMAN Glucose-6-phosphate isomerase (Fragment) OS=Homo sapiens GN=GPI PE=4 SV=1 76572 TSGQRPAKRRRKSPAMAALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQREARVQ 490 18.2 2 31 3 8 1 0.744 0.583 0.388 3 3 3 - * * 0.571666666666667 0.178270393877765 tr|A0A0A0MTS2|A0A0A0MTS2_HUMAN 100.00 0.0 gi|14488680|pdb|1IAT|A Chain A, Crystal Structure Of Human Phosphoglucose IsomeraseNEUROLEUKINAUTOCRINE MOTILITY FACTORMATURATION FACTOR 100.00 0.0 sp|P06744|G6PI_HUMAN Glucose-6-phosphate isomerase OS=Homo sapiens GN=GPI PE=1 SV=4 99.23 0.0 G8F3L1 G8F3L1_MACFA Glucose-6-phosphate isomerase (Fragment) OS=Macaca fascicularis GN=EGM_20016 PE=3 SV=1 YPO3718 746 0.0 COG0166 Glucose-6-phosphate isomerase G Carbohydrate transport and metabolism ; K01810|1|0.0|1169|hsa:2821|glucose-6-phosphate isomerase [EC:5.3.1.9] GO:0001525//angiogenesis;GO:0006094//gluconeogenesis;GO:0007599//hemostasis;GO:0007611//learning or memory;GO:0006959//humoral immune response;GO:0051156//glucose 6-phosphate metabolic process;GO:0046185//aldehyde catabolic process;GO:0006096//glycolysis;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044281//small molecule metabolic process;GO:0019242//methylglyoxal biosynthetic process;GO:0043524//negative regulation of neuron apoptotic process GO:0004347//glucose-6-phosphate isomerase activity;GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0048029//monosaccharide binding;GO:0016866//intramolecular transferase activity GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005886//plasma membrane 95 tr|A0A024R5M3|A0A024R5M3_HUMAN Cortactin, isoform CRA_c OS=Homo sapiens GN=CTTN PE=4 SV=1 71900 MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKEKEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPVYEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ 141 8.0 2 7 7 3 3 0.616 0.659 0.412 5 6 5 * - * 0.562333333333333 0.131955800680885 tr|A0A024R5M3|A0A024R5M3_HUMAN 100.00 1e-28 gi|99032005|pdb|2D1X|A Chain A, The Crystal Structure Of The Cortactin-Sh3 Domain And Amap1- Peptide Complex >gi|99032006|pdb|2D1X|B Chain B, The Crystal Structure Of The Cortactin-Sh3 Domain And Amap1- Peptide Complex >gi|99032007|pdb|2D1X|C Chain C, The Crystal Structure Of The Cortactin-Sh3 Domain And Amap1- Peptide Complex >gi|99032008|pdb|2D1X|D Chain D, The Crystal Structure Of The Cortactin-Sh3 Domain And Amap1- Peptide Complex 93.27 0.0 sp|Q14247|SRC8_HUMAN Src substrate cortactin OS=Homo sapiens GN=CTTN PE=1 SV=2 100.00 6e-115 H7C314 H7C314_HUMAN Src substrate cortactin (Fragment) OS=Homo sapiens GN=CTTN PE=4 SV=1 - - - - - - - K06106|1|0.0|952|pon:100174046|cortactin GO:0006898//receptor-mediated endocytosis GO:0070064//proline-rich region binding GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0001726//ruffle;GO:0030027//lamellipodium 96 sp|Q15942|ZYX_HUMAN Zyxin OS=Homo sapiens GN=ZYX PE=1 SV=1 70649 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAPGGSGSQPNQKLGHPEALSAGTGSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARAQT 252 14.5 - 22 22 5 5 0.754 0.770 0.597 13 13 13 * - * 0.707 0.09559811713627 sp|Q15942|ZYX_HUMAN 100.00 2e-17 gi|386782137|ref|NP_001247977.1| zyxin [Macaca mulatta] 100.00 2e-18 sp|Q15942|ZYX_HUMAN Zyxin OS=Homo sapiens GN=ZYX PE=1 SV=1 100.00 7e-17 G3S1P9 G3S1P9_GORGO Uncharacterized protein OS=Gorilla gorilla gorilla GN=ZYX PE=4 SV=1 - - - - - - - K06273|1|8e-165|580|hsa:7791|zyxin GO:0007267//cell-cell signaling;GO:0007165//signal transduction GO:0005515//protein binding GO:0005913//cell-cell adherens junction;GO:0001725//stress fiber;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0005887//integral to plasma membrane 97 tr|Q6IPN0|Q6IPN0_HUMAN Reticulon OS=Homo sapiens GN=RTN4 PE=2 SV=1 42124 MEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE 350 16.6 2 9 9 3 3 0.535 0.546 0.417 7 7 8 * * * 0.499333333333333 0.0715145672806131 tr|Q6IPN0|Q6IPN0_HUMAN 100.00 1e-60 gi|444706536|gb|ELW47873.1| Reticulon-4 [Tupaia chinensis] 98.44 3e-67 sp|Q9NQC3|RTN4_HUMAN Reticulon-4 OS=Homo sapiens GN=RTN4 PE=1 SV=2 100.00 2e-66 Q4FZ93 Q4FZ93_PANTR RTN4-C OS=Pan troglodytes GN=LOC100609668 PE=2 SV=1 - - - - - - - K00688|1|5e-16|85.9|ame:409267|starch phosphorylase [EC:2.4.1.1] GO:0001525//angiogenesis;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0045665//negative regulation of neuron differentiation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0021801//cerebral cortex radial glia guided migration;GO:0033603//positive regulation of dopamine secretion;GO:0030334//regulation of cell migration;GO:0048679//regulation of axon regeneration;GO:0071786//endoplasmic reticulum tubular network organization;GO:0045687//positive regulation of glial cell differentiation;GO:2000172//regulation of branching morphogenesis of a nerve;GO:0070571//negative regulation of neuron projection regeneration;GO:0030517//negative regulation of axon extension;GO:0007413//axonal fasciculation;GO:0051930//regulation of sensory perception of pain GO:0032403//protein complex binding GO:0043005//neuron projection;GO:0030176//integral to endoplasmic reticulum membrane;GO:0043209//myelin sheath;GO:0005635//nuclear envelope;GO:0043025//neuronal cell body;GO:0043234//protein complex;GO:0005886//plasma membrane 98 tr|G3V1A4|G3V1A4_HUMAN Cofilin 1 (Non-muscle), isoform CRA_a OS=Homo sapiens GN=CFL1 PE=1 SV=1 24634 MKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL 822 50.3 2 43 24 9 6 0.392 0.307 0.349 15 15 15 * * * 0.349333333333333 0.0425009803808493 tr|G3V1A4|G3V1A4_HUMAN 100.00 6e-81 gi|403293515|ref|XP_003937759.1| PREDICTED: EGF-containing fibulin-like extracellular matrix protein 2 [Saimiri boliviensis boliviensis] 100.00 1e-81 sp|P23528|COF1_HUMAN Cofilin-1 OS=Homo sapiens GN=CFL1 PE=1 SV=3 100.00 3e-80 H2Q279 H2Q279_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000172757 PE=4 SV=1 - - - - - - - K05765|1|1e-81|301|ecb:100057603|cofilin GO:0007411//axon guidance;GO:0009615//response to virus;GO:0007266//Rho protein signal transduction;GO:0022604//regulation of cell morphogenesis;GO:0001842//neural fold formation;GO:0030168//platelet activation;GO:0001755//neural crest cell migration;GO:0030836//positive regulation of actin filament depolymerization;GO:0006468//protein phosphorylation;GO:0045792//negative regulation of cell size;GO:0043200//response to amino acid stimulus;GO:0002576//platelet degranulation;GO:0030010//establishment of cell polarity;GO:0006606//protein import into nucleus;GO:0000910//cytokinesis GO:0003779//actin binding GO:0032587//ruffle membrane;GO:0016363//nuclear matrix;GO:0031258//lamellipodium membrane;GO:0030864//cortical actin cytoskeleton 99 tr|Q53FP8|Q53FP8_HUMAN Calponin (Fragment) OS=Homo sapiens PE=2 SV=1 40637 MSSAHFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGNNFMDGLKDGIILCEFINKLQPGSVKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKTKGNKVNVGVKYAEKQERKFEPGKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQATISQQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTPEYPELGEPAHNHHAHNYYNSA 156 7.4 1 6 6 2 2 0.496 0.576 0.421 4 4 4 * - * 0.497666666666667 0.0775134396948899 tr|Q53FP8|Q53FP8_HUMAN 100.00 7e-162 gi|62898029|dbj|BAD96954.1| calponin 1, basic, smooth muscle variant [Homo sapiens] 99.65 6e-162 sp|P51911|CNN1_HUMAN Calponin-1 OS=Homo sapiens GN=CNN1 PE=1 SV=2 100.00 3e-161 Q53FP8 Q53FP8_HUMAN Calponin 1, basic, smooth muscle variant (Fragment) OS=Homo sapiens PE=2 SV=1 ECU03g1150 71.2 2e-12 COG5199 Calponin Z Cytoskeleton ; K06084|1|2e-13|77.0|bfo:BRAFLDRAFT_117217|F-box protein 20 GO:0006940//regulation of smooth muscle contraction;GO:0031032//actomyosin structure organization GO:0003779//actin binding;GO:0005516//calmodulin binding GO:0005856//cytoskeleton 100 tr|E9PBG7|E9PBG7_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CAMK2D PE=1 SV=1 70161 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKINNKANVVTSPKENIPTPALEPQTTVIHNPDGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 107 7.6 - 4 4 3 3 0.706 0.390 0.780 3 3 3 * * - 0.625333333333333 0.207136026159945 tr|E9PBG7|E9PBG7_HUMAN 100.00 0.0 gi|402870282|ref|XP_003899161.1| PREDICTED: calcium/calmodulin-dependent protein kinase type II subunit delta isoform 4 [Papio anubis] 98.24 0.0 sp|O77708|KCC2D_RABIT Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Oryctolagus cuniculus GN=CAMK2D PE=2 SV=2 100.00 0.0 E9Q1V9 E9Q1V9_MOUSE Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Mus musculus GN=Camk2d PE=4 SV=1 SPAC14C4.03 167 5e-41 COG0515 Serine/threonine protein kinase RTKL General function prediction only ; Signal transduction mechanisms ; Transcription ; Replication, recombination and repair ; K04515|1|0.0|1073|mcc:702504|calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] GO:0006468//protein phosphorylation GO:0004683//calmodulin-dependent protein kinase activity;GO:0005524//ATP binding;GO:0005516//calmodulin binding - 101 tr|A0A087WW43|A0A087WW43_HUMAN Inter-alpha-trypsin inhibitor heavy chain H3 OS=Homo sapiens GN=ITIH3 PE=4 SV=1 89310 MAFAWWPCLILALLSSLAASGFPRSPFRLLGKRSLPEGVANGIEVYSTKINSKVTSRFAHNVVTMRAVNRADTAKEVSFDVELPKTAFITNFTLTIDGVTYPGNVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVKHFEIEVDIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTITYDVNRESPGNVQIVNGYFVHFFAPQGLPVVPKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKEHLVQATPENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGFARRIYEDSDADLQLQGFYEEVANPLLTGVEMEYPENAILDLTQNTYQHFYDGSEIVVAGRLVDEDMNSFKADVKGHGATNDLTFTEEVDMKEMEKALQERDYIFGNYIERLWAYLTIEQLLEKRKNAHGEEKENLTARALDLSLKYHFVTPLTSMVVTKPEDNEDERAIADKPGEGGDSHTGEPRHVLPDQLPASSKPLLLCGRGSPLHHPNSGERRCPLLQHR 210 4.6 3 10 10 3 3 0.789 0.625 0.549 5 5 6 - * * 0.654333333333333 0.122659420075807 tr|A0A087WW43|A0A087WW43_HUMAN 99.85 0.0 gi|119585666|gb|EAW65262.1| inter-alpha (globulin) inhibitor H3, isoform CRA_a [Homo sapiens] 98.73 0.0 sp|Q06033|ITIH3_HUMAN Inter-alpha-trypsin inhibitor heavy chain H3 OS=Homo sapiens GN=ITIH3 PE=1 SV=2 100.00 0.0 C9JX84 C9JX84_HUMAN Inter-alpha-trypsin inhibitor heavy chain H3 OS=Homo sapiens GN=ITIH3 PE=4 SV=2 alr4412 102 2e-21 COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R General function prediction only ; K05316|1|1e-09|65.5|dmo:Dmoj_GI17296|voltage-dependent calcium channel alpha-2/delta, invertebrate GO:0030212//hyaluronan metabolic process;GO:0010951//negative regulation of endopeptidase activity GO:0004867//serine-type endopeptidase inhibitor activity GO:0005576//extracellular region 102 tr|Q53GN4|Q53GN4_HUMAN WD repeat domain 1, isoform CRA_a (Fragment) OS=Homo sapiens GN=WDR1 PE=2 SV=1 79295 MPYEIKKVFASLPQVERGVSKIIGGDPKGNNFLYTNGKCVILRNIDNPALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSDDNCAAFFEGPPFKFKFTVGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYWDSETGENDSFAGKGHTNQVSRMTVDESGQLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQIVLLKDQRKCFSIDNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTITY 473 18.6 3 26 26 9 9 0.618 0.509 0.410 18 18 17 - * * 0.512333333333333 0.104040056388553 tr|Q53GN4|Q53GN4_HUMAN 100.00 2e-124 gi|50949306|emb|CAB53674.2| hypothetical protein [Homo sapiens] 99.83 0.0 sp|O75083|WDR1_HUMAN WD repeat-containing protein 1 OS=Homo sapiens GN=WDR1 PE=1 SV=4 100.00 0.0 Q53GN4 Q53GN4_HUMAN WD repeat domain 1, isoform CRA_a (Fragment) OS=Homo sapiens GN=WDR1 PE=2 SV=1 MA2525 116 1e-25 COG2319 FOG: WD40 repeat R General function prediction only ; K12662|1|7e-17|89.4|api:100163110|U4/U6 small nuclear ribonucleoprotein PRP4!K14963|3|1e-16|88.6|cin:100176938|COMPASS component SWD3 GO:0007605//sensory perception of sound;GO:0002576//platelet degranulation;GO:0030168//platelet activation GO:0003779//actin binding GO:0005856//cytoskeleton;GO:0005576//extracellular region;GO:0005829//cytosol 103 sp|P07437|TBB5_HUMAN Tubulin beta chain OS=Homo sapiens GN=TUBB PE=1 SV=2 >tr|Q5SU16|Q5SU16_HUMAN Beta 5-tubulin OS=Homo sapiens GN=TUBB PE=2 SV=1 54962 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA 742 32.9 - 43 13 11 3 0.502 0.251 0.278 11 9 8 * * * 0.343666666666667 0.1377836468284 sp|P07437|TBB5_HUMAN 100.00 0.0 gi|470614409|ref|XP_004316708.1| PREDICTED: tubulin beta chain-like [Tursiops truncatus] 100.00 0.0 sp|Q91575|TBB5_XENLA Tubulin beta chain OS=Xenopus laevis GN=tubb PE=2 SV=1 100.00 0.0 H9GP30 H9GP30_ANOCA Uncharacterized protein OS=Anolis carolinensis GN=TUBB PE=4 SV=1 ECU03g0820i 749 0.0 COG5023 Tubulin Z Cytoskeleton ; K07375|1|0.0|856|acs:100563630|tubulin beta GO:0001764//neuron migration;GO:0042267//natural killer cell mediated cytotoxicity;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0051301//cell division;GO:0006184//GTP catabolic process;GO:0051225//spindle assembly;GO:0051258//protein polymerization;GO:0007067//mitosis;GO:0007018//microtubule-based movement;GO:0000086//G2/M transition of mitotic cell cycle;GO:0030182//neuron differentiation GO:0005525//GTP binding;GO:0042288//MHC class I protein binding;GO:0042277//peptide binding;GO:0032403//protein complex binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton GO:0045298//tubulin complex;GO:0044297//cell body;GO:0005641//nuclear envelope lumen;GO:0005829//cytosol;GO:0005874//microtubule 104 tr|Q59E93|Q59E93_HUMAN Membrane alanine aminopeptidase variant (Fragment) OS=Homo sapiens PE=2 SV=1 124916 GSLSRLPTITMAKGFYISKSLGILGILLGVAAVCTIIALSVVYSQEKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYNEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWFTENSK 738 14.7 1 51 51 14 14 0.650 0.757 0.664 29 29 27 * * * 0.690333333333333 0.0581578312296232 tr|Q59E93|Q59E93_HUMAN 100.00 0.0 gi|62089422|dbj|BAD93155.1| membrane alanine aminopeptidase precursor variant [Homo sapiens] 99.90 0.0 sp|P15144|AMPN_HUMAN Aminopeptidase N OS=Homo sapiens GN=ANPEP PE=1 SV=4 100.00 0.0 Q59E93 Q59E93_HUMAN Membrane alanine aminopeptidase variant (Fragment) OS=Homo sapiens PE=2 SV=1 YHR047c 393 1e-108 COG0308 Aminopeptidase N E Amino acid transport and metabolism ; K11140|1|0.0|1875|hsa:290|aminopeptidase N [EC:3.4.11.2] GO:0001525//angiogenesis;GO:0035814//negative regulation of renal sodium excretion;GO:0006508//proteolysis;GO:0030154//cell differentiation;GO:0006725//cellular aromatic compound metabolic process;GO:0019048//virus-host interaction GO:0042277//peptide binding;GO:0008270//zinc ion binding;GO:0004872//receptor activity;GO:0004177//aminopeptidase activity;GO:0008237//metallopeptidase activity GO:0031983//vesicle lumen;GO:0005829//cytosol;GO:0009897//external side of plasma membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0012506//vesicle membrane;GO:0005887//integral to plasma membrane 105 sp|P30086|PEBP1_HUMAN Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens GN=PEBP1 PE=1 SV=3 >tr|D9IAI1|D9IAI1_HUMAN Epididymis secretory protein Li 34 OS=Homo sapiens GN=PEBP1 PE=2 SV=1 26025 MPVDLSKWSGPLSLQEVDEQPQHPLHVTYAGAAVDELGKVLTPTQVKNRPTSISWDGLDSGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNDISSGTVLSDYVGSGPPKGTGLHRYVWLVYEQDRPLKCDEPILSNRSGDHRGKFKVASFRKKYELRAPVAGTCYQAEWDDYVPKLYEQLSGK 645 43.3 - 41 41 6 6 0.761 0.665 0.668 24 24 24 - * * 0.698 0.0545802161959807 sp|P30086|PEBP1_HUMAN 100.00 8e-78 gi|4261934|gb|AAD14234.1|S76773_1 neuropolypeptide h3, partial [Homo sapiens] 100.00 8e-107 sp|P30086|PEBP1_HUMAN Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens GN=PEBP1 PE=1 SV=3 100.00 2e-105 H2Q6Z4 H2Q6Z4_PANTR Uncharacterized protein OS=Pan troglodytes GN=ENSG00000089220 PE=4 SV=1 YLR178c 62.8 3e-10 COG1881 Phospholipid-binding protein R General function prediction only ; K14802|1|2e-08|58.5|dan:Dana_GF11187|phospholipid-transporting ATPase [EC:3.6.3.1] GO:0009611//response to wounding;GO:0051602//response to electrical stimulus;GO:0010243//response to organic nitrogen;GO:0051412//response to corticosterone stimulus;GO:0014823//response to activity;GO:0045471//response to ethanol;GO:0042755//eating behavior;GO:0051592//response to calcium ion;GO:0007568//aging;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0001933//negative regulation of protein phosphorylation;GO:0007420//brain development;GO:0014070//response to organic cyclic compound;GO:0043409//negative regulation of MAPK cascade;GO:0007286//spermatid development;GO:0042493//response to drug;GO:0051591//response to cAMP;GO:0009408//response to heat;GO:0045840//positive regulation of mitosis;GO:0009636//response to toxic substance;GO:0002026//regulation of the force of heart contraction;GO:0060409//positive regulation of acetylcholine metabolic process;GO:0006979//response to oxidative stress;GO:0010466//negative regulation of peptidase activity GO:0051019//mitogen-activated protein kinase binding;GO:0005102//receptor binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008429//phosphatidylethanolamine binding;GO:0005524//ATP binding GO:0043679//axon terminus;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005741//mitochondrial outer membrane;GO:0009986//cell surface;GO:0043025//neuronal cell body;GO:0008021//synaptic vesicle;GO:0045177//apical part of cell;GO:0005791//rough endoplasmic reticulum 106 sp|P06733|ENOA_HUMAN Alpha-enolase OS=Homo sapiens GN=ENO1 PE=1 SV=2 >tr|A0A024R4F1|A0A024R4F1_HUMAN Enolase 1, (Alpha), isoform CRA_a OS=Homo sapiens GN=ENO1 PE=3 SV=1 59345 MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVVIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFRNPLAK 2968 38.7 - 127 108 13 11 0.888 0.733 0.752 81 80 82 * * * 0.791 0.0845399313933954 sp|P06733|ENOA_HUMAN 100.00 0.0 gi|203282367|pdb|3B97|A Chain A, Crystal Structure Of Human Enolase 1 >gi|203282368|pdb|3B97|B Chain B, Crystal Structure Of Human Enolase 1 >gi|203282369|pdb|3B97|C Chain C, Crystal Structure Of Human Enolase 1 >gi|203282370|pdb|3B97|D Chain D, Crystal Structure Of Human Enolase 1 100.00 0.0 sp|P06733|ENOA_HUMAN Alpha-enolase OS=Homo sapiens GN=ENO1 PE=1 SV=2 100.00 0.0 G2HFA5 G2HFA5_PANTR Alpha-enolase OS=Pan troglodytes GN=ENSG00000074800 PE=2 SV=1 YGR254w 567 1e-161 COG0148 Enolase G Carbohydrate transport and metabolism ; K01689|1|0.0|893|ptr:457913|enolase [EC:4.2.1.11] GO:0009615//response to virus;GO:0030308//negative regulation of cell growth;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006096//glycolysis;GO:0006094//gluconeogenesis;GO:0044281//small molecule metabolic process GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0000287//magnesium ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0004634//phosphopyruvate hydratase activity GO:0031430//M band;GO:0000015//phosphopyruvate hydratase complex;GO:0009986//cell surface;GO:0005634//nucleus;GO:0005886//plasma membrane 107 sp|Q9UDY4|DNJB4_HUMAN DnaJ homolog subfamily B member 4 OS=Homo sapiens GN=DNAJB4 PE=1 SV=1 47746 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGRDSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPVIHELRVSLEEIYSGCTKRMKISRKRLNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKDHPKFKRDGSNIIYTAKISLREALCGCSINVPTLDGRNIPMSVNDIVKPGMRRRIIGYGLPFPKNPDQRGDLLIEFEVSFPDTISSSSKEVLRKHLPAS 83 11.0 2 5 5 3 3 0.284 0.361 0.277 2 2 2 * * * 0.307333333333333 0.0466082968293557 sp|Q9UDY4|DNJB4_HUMAN 100.00 2e-125 gi|119626760|gb|EAX06355.1| DnaJ (Hsp40) homolog, subfamily B, member 4, isoform CRA_b [Homo sapiens] 100.00 0.0 sp|Q9UDY4|DNJB4_HUMAN DnaJ homolog subfamily B member 4 OS=Homo sapiens GN=DNAJB4 PE=1 SV=1 100.00 7e-125 B4DNN2 B4DNN2_HUMAN DnaJ (Hsp40) homolog, subfamily B, member 4, isoform CRA_b OS=Homo sapiens GN=DNAJB4 PE=2 SV=1 slr0093 150 4e-36 COG2214 DnaJ-class molecular chaperone O Posttranslational modification, protein turnover, chaperones ; K09510|1|0.0|647|ptr:100608554|DnaJ homolog subfamily B member 4 GO:0006457//protein folding;GO:0006986//response to unfolded protein;GO:0009408//response to heat GO:0031072//heat shock protein binding;GO:0051082//unfolded protein binding GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane 108 sp|Q09666|AHNK_HUMAN Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens GN=AHNAK PE=1 SV=2 881095 MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATIYFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLSGDDEEYQRIYTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSPEFKIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGPSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKVGIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAEASSPKGKFSLFKSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGKHGKLKFGTFGGLGSKSKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPEVELSVSTKKE 4307 17.4 - 189 140 71 59 0.770 0.797 0.744 111 112 108 * * * 0.770333333333333 0.0265015722804013 sp|Q09666|AHNK_HUMAN 100.00 0.0 gi|61743954|ref|NP_001611.1| neuroblast differentiation-associated protein AHNAK isoform 1 [Homo sapiens] >gi|160332335|sp|Q09666.2|AHNK_HUMAN RecName: Full=Neuroblast differentiation-associated protein AHNAK; AltName: Full=Desmoyokin 100.00 0.0 sp|Q09666|AHNK_HUMAN Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens GN=AHNAK PE=1 SV=2 100.00 1e-45 E9PLZ1 E9PLZ1_HUMAN Neuroblast differentiation-associated protein AHNAK (Fragment) OS=Homo sapiens GN=AHNAK PE=4 SV=1 - - - - - - - - GO:0007399//nervous system development GO:0005515//protein binding GO:0005634//nucleus 109 tr|D3YTG3|D3YTG3_HUMAN Target of Nesh-SH3 OS=Homo sapiens GN=ABI3BP PE=4 SV=1 237869 MRGGKCNMLSSLGCLLLCGSITLALGNAQKLPKGKRPNLKVHINTTSDSILLKFLRPSPNVKLEGLLLGYGSNVSPNQYFPLPAEGKFTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTLPSHCPNDRFYTIRYREKDKEKKWIFQICPATETIVENLKPNTVYEFGVKDNVEGGIWSKIFNHKTVVGSKKVNGKIQSTYDQDHTVPAYVPRKLIPITIIKQVIQNVTHKDSAKSPEKAPLGGVILVHLIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLVLSKRTPETLQTILIPQFELPLSTLAPKSLPEFPEAKTPFPFEKPRGTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVPKSKPALEPATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTKSVSEPVPFETEAPSMTIVPTTDIEPVTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDFGPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIFEPVSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPSPEVPQTKLVPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPKTTSSPEVPQNKSVSVTGFEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESQPVSDVLESVTLSTESPKETIAPAKTDYVYPTAKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPVLNRTTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNSPCSITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLSDSLTGKFYNIGDQRGHGEDHCQFVDSFLDGRTGQQLTSDQLPIKEGYFRAVRQEPVQFGEIGGHTQINYVQWYECGTTIPGKW 758 8.7 1 51 51 13 13 0.409 0.222 0.283 31 30 31 * * * 0.304666666666667 0.0953642141127023 tr|D3YTG3|D3YTG3_HUMAN 100.00 0.0 gi|119600216|gb|EAW79810.1| ABI gene family, member 3 (NESH) binding protein, isoform CRA_g [Homo sapiens] 94.80 0.0 sp|Q7Z7G0|TARSH_HUMAN Target of Nesh-SH3 OS=Homo sapiens GN=ABI3BP PE=1 SV=1 100.00 2e-67 H7C4S3 H7C4S3_HUMAN Target of Nesh-SH3 (Fragment) OS=Homo sapiens GN=ABI3BP PE=4 SV=1 - - - - - - - K06759|1|8e-06|54.7|acs:100557818|contactin 1 - - GO:0031012//extracellular matrix;GO:0005615//extracellular space 110 sp|P61158|ARP3_HUMAN Actin-related protein 3 OS=Homo sapiens GN=ACTR3 PE=1 SV=3 >tr|A0A024RAI1|A0A024RAI1_HUMAN ARP3 actin-related protein 3 homolog (Yeast), isoform CRA_a OS=Homo sapiens GN=ACTR3 PE=3 SV=1 55098 MAGRLPACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDFFIGDEAIEKPTYATKWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTPEFYQVCHTKKDYEEIGPSICRHNPVFGVMS 466 37.1 - 25 25 11 11 0.936 0.759 0.771 16 16 17 - * * 0.822 0.0989090491310072 sp|P61158|ARP3_HUMAN 100.00 0.0 gi|466042071|ref|XP_004276540.1| PREDICTED: actin-related protein 3-like isoform 3 [Orcinus orca] 100.00 0.0 sp|P61158|ARP3_HUMAN Actin-related protein 3 OS=Homo sapiens GN=ACTR3 PE=1 SV=3 100.00 4e-169 F6UPC4 F6UPC4_CALJA Uncharacterized protein OS=Callithrix jacchus GN=ACTR3 PE=3 SV=1 SPAC630.03 488 7e-138 COG5277 Actin and related proteins Z Cytoskeleton ; K05692|1|9e-69|261|xla:100036902|actin beta/gamma 1 GO:0050775//positive regulation of dendrite morphogenesis;GO:0007163//establishment or maintenance of cell polarity;GO:0060271//cilium morphogenesis;GO:0046677//response to antibiotic;GO:0051321//meiotic cell cycle;GO:0006928//cellular component movement;GO:0008356//asymmetric cell division;GO:0043519//regulation of myosin II filament organization;GO:0045666//positive regulation of neuron differentiation;GO:0033206//cytokinesis after meiosis;GO:0051653//spindle localization;GO:0010592//positive regulation of lamellipodium assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0009743//response to carbohydrate stimulus;GO:0051491//positive regulation of filopodium assembly GO:0003779//actin binding;GO:0005524//ATP binding GO:0030056//hemidesmosome;GO:0030027//lamellipodium;GO:0000139//Golgi membrane;GO:0005884//actin filament;GO:0060076//excitatory synapse;GO:0005885//Arp2/3 protein complex;GO:0002102//podosome 111 sp|P04075|ALDOA_HUMAN Fructose-bisphosphate aldolase A OS=Homo sapiens GN=ALDOA PE=1 SV=2 >tr|V9HWN7|V9HWN7_HUMAN Fructose-bisphosphate aldolase OS=Homo sapiens GN=HEL-S-87p PE=2 SV=1 48065 MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFVSNHAY 850 51.6 - 42 41 11 10 0.509 0.445 0.431 29 30 29 * * * 0.461666666666667 0.0415852537966685 sp|P04075|ALDOA_HUMAN 100.00 0.0 gi|4557305|ref|NP_000025.1| fructose-bisphosphate aldolase A isoform 1 [Homo sapiens] >gi|34577110|ref|NP_908930.1| fructose-bisphosphate aldolase A isoform 1 [Homo sapiens] >gi|34577112|ref|NP_908932.1| fructose-bisphosphate aldolase A isoform 1 [Homo sapiens] >gi|193794814|ref|NP_001121089.1| fructose-bisphosphate aldolase A isoform 1 [Homo sapiens] >gi|113606|sp|P04075.2|ALDOA_HUMAN RecName: Full=Fructose-bisphosphate aldolase A; AltName: Full=Lung cancer antigen NY-LU-1; AltName: Full=Muscle-type aldolase >gi|178351|gb|AAA51690.1| aldolase A (EC 4.1.3.13) [Homo sapiens] >gi|13279257|gb|AAH04333.1| Aldolase A, fructose-bisphosphate [Homo sapiens] >gi|14715001|gb|AAH10660.1| Aldolase A, fructose-bisphosphate [Homo sapiens] >gi|15277571|gb|AAH12880.1| Aldolase A, fructose-bisphosphate [Homo sapiens] >gi|15488981|gb|AAH13614.1| Aldolase A, fructose-bisphosphate [Homo sapiens] >gi|16198435|gb|AAH15888.1| Aldolase A, fructose-bisphosphate [Homo sapiens] >gi|16877049|gb|AAH16800.1| Aldolase A, fructose-bisphosphate [Homo sapiens] >gi|49168540|emb|CAG38765.1| ALDOA [Homo sapiens] >gi|119600339|gb|EAW79933.1| aldolase A, fructose-bisphosphate, isoform CRA_a [Homo sapiens] >gi|119600340|gb|EAW79934.1| aldolase A, fructose-bisphosphate, isoform CRA_a [Homo sapiens] >gi|119600341|gb|EAW79935.1| aldolase A, fructose-bisphosphate, isoform CRA_a [Homo sapiens] >gi|343959624|dbj|BAK63669.1| fructose-bisphosphate aldolase A [Pan troglodytes] 100.00 0.0 sp|P04075|ALDOA_HUMAN Fructose-bisphosphate aldolase A OS=Homo sapiens GN=ALDOA PE=1 SV=2 100.00 0.0 G2HIW1 G2HIW1_PANTR Fructose-bisphosphate aldolase OS=Pan troglodytes GN=ALDOA PE=2 SV=1 AGl2190 343 4e-94 COG3588 Fructose-1,6-bisphosphate aldolase G Carbohydrate transport and metabolism ; K01623|1|0.0|714|hsa:226|fructose-bisphosphate aldolase, class I [EC:4.1.2.13] GO:0006094//gluconeogenesis;GO:0006941//striated muscle contraction;GO:0008360//regulation of cell shape;GO:0030168//platelet activation;GO:0051289//protein homotetramerization;GO:0006000//fructose metabolic process;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0006754//ATP biosynthetic process;GO:0006096//glycolysis;GO:0007015//actin filament organization;GO:0046716//muscle cell homeostasis;GO:0002576//platelet degranulation GO:0003779//actin binding;GO:0042802//identical protein binding;GO:0015631//tubulin binding;GO:0070061//fructose binding;GO:0004332//fructose-bisphosphate aldolase activity GO:0031093//platelet alpha granule lumen;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0031674//I band;GO:0070062//extracellular vesicular exosome 112 tr|A0A023T695|A0A023T695_HUMAN Septin 7 variant 4 OS=Homo sapiens PE=2 SV=1 60777 MLPVANLELLGSSDPSALASQSARITGESGLGKSTLINSLFLTDLYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKNKKKGKIF 148 5.4 14 10 10 2 2 0.887 0.700 0.666 7 7 7 - * * 0.751 0.119 tr|A0A023T695|A0A023T695_HUMAN 100.00 0.0 gi|296209064|ref|XP_002751374.1| PREDICTED: septin-7 isoform 3 [Callithrix jacchus] >gi|397527041|ref|XP_003833415.1| PREDICTED: septin-7 isoform 3 [Pan paniscus] >gi|402863733|ref|XP_003896156.1| PREDICTED: septin-7 isoform 2 [Papio anubis] >gi|410952658|ref|XP_003982996.1| PREDICTED: septin-7 isoform 3 [Felis catus] >gi|471407559|ref|XP_004385366.1| PREDICTED: septin-7 isoform 3 [Trichechus manatus latirostris] >gi|194388476|dbj|BAG60206.1| unnamed protein product [Homo sapiens] 99.48 0.0 sp|Q16181|SEPT7_HUMAN Septin-7 OS=Homo sapiens GN=SEPT7 PE=1 SV=2 100.00 0.0 F7IPV7 F7IPV7_CALJA Uncharacterized protein OS=Callithrix jacchus GN=SEPT7 PE=3 SV=1 SPAC4F10.11 305 1e-82 COG5019 Septin family protein DZ Cell cycle control, cell division, chromosome partitioning ; Cytoskeleton ; K04557|1|1e-94|347|dre:335925|peanut-like protein 1 (cell division control related protein 1) GO:0060271//cilium morphogenesis;GO:0051291//protein heterooligomerization;GO:0000910//cytokinesis;GO:0016476//regulation of embryonic cell shape;GO:0007067//mitosis GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005525//GTP binding GO:0035085//cilium axoneme;GO:0005730//nucleolus;GO:0030496//midbody;GO:0045202//synapse;GO:0031105//septin complex;GO:0001725//stress fiber;GO:0032154//cleavage furrow;GO:0005819//spindle;GO:0016324//apical plasma membrane;GO:0000777//condensed chromosome kinetochore;GO:0043679//axon terminus 113 tr|B3KR70|B3KR70_HUMAN cDNA FLJ33764 fis, clone BRCOC2000360, highly similar to Vacuolar ATP synthase subunit S1 (EC 3.6.3.14) OS=Homo sapiens PE=2 SV=1 51864 MRPRLTAPLLCPARDLWAPAADTHEGHITSDLQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFSNLENALDLAPSSLVLPAVDWYAVSTLTTYLQEKLGASPLHVDLATLRELKLNASLPALLLIRLPYTASSGLMAPREVLTGNDEVIGQVLSTLKSEDVPYTAALTAVRPSRVARDVAVVAGGLGRQLLQKQPVSPVIHPPVSYNDTAPRILFWAQNFSVAYKDQWEDLTPLTFGVQELNLTGSFWNDSFARLSLTYERLFGTTVTFKFILANRLYPVSARHWFTMERLEVHSNGSVAYFNASQVTGSSIYSFHCEYVSSLSKKGSLLVARTQPSPWQMMLQDFQIQAFNVMGEQFSYASDCASFFSPGIWMGLLTSLFMLFIFTYGLHMILSLKTMDRFDDHKGPTISLTQIV 317 14.0 1 12 12 4 4 0.873 0.659 0.741 7 8 8 - * * 0.757666666666667 0.107969131391029 tr|B3KR70|B3KR70_HUMAN 100.00 0.0 gi|193786959|dbj|BAG52282.1| unnamed protein product [Homo sapiens] 99.76 0.0 sp|Q15904|VAS1_HUMAN V-type proton ATPase subunit S1 OS=Homo sapiens GN=ATP6AP1 PE=1 SV=2 100.00 9e-54 A6NLC6 A6NLC6_HUMAN ATPase, H+ transporting, lysosomal accessory protein 1 (Fragment) OS=Homo sapiens GN=ATP6AP1 PE=4 SV=3 - - - - - - - K03662|1|0.0|749|hsa:537|V-type H+-transporting ATPase S1 subunit [EC:3.6.3.14] GO:0008219//cell death;GO:0007568//aging;GO:0015991//ATP hydrolysis coupled proton transport GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0005524//ATP binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism GO:0016021//integral to membrane;GO:0005774//vacuolar membrane;GO:0033180//proton-transporting V-type ATPase, V1 domain 114 tr|B3KQF5|B3KQF5_HUMAN cDNA FLJ90381 fis, clone NT2RP2005035, highly similar to Calumenin OS=Homo sapiens PE=2 SV=1 46236 MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKTFDQLTPEESKERLGKIVSKIDGDKDGFVTVDELKDWIKFAQKRWIYEDVERQWKGHDLNEDGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMGKVETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF 1151 42.2 1 70 16 12 5 0.693 0.501 0.697 12 12 12 * - * 0.630333333333333 0.112023806993573 tr|B3KQF5|B3KQF5_HUMAN 100.00 1e-122 gi|410952803|ref|XP_003983067.1| PREDICTED: calumenin isoform 3 [Felis catus] 99.37 0.0 sp|O43852|CALU_HUMAN Calumenin OS=Homo sapiens GN=CALU PE=1 SV=2 100.00 5e-122 F5H879 F5H879_HUMAN Calumenin OS=Homo sapiens GN=CALU PE=4 SV=1 - - - - - - - - GO:0002576//platelet degranulation;GO:0030168//platelet activation GO:0005515//protein binding;GO:0005509//calcium ion binding GO:0005794//Golgi apparatus;GO:0042470//melanosome;GO:0033018//sarcoplasmic reticulum lumen;GO:0005576//extracellular region 115 tr|Q5T9B7|Q5T9B7_HUMAN Adenylate kinase isoenzyme 1 OS=Homo sapiens GN=AK1 PE=1 SV=1 29708 MGCCSSSDPRREDDLRAREKLKKTKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK 161 10.0 2 8 8 2 2 0.729 0.813 0.607 4 4 4 * - * 0.716333333333333 0.103582495303663 tr|Q5T9B7|Q5T9B7_HUMAN 100.00 7e-107 gi|4502011|ref|NP_000467.1| adenylate kinase isoenzyme 1 [Homo sapiens] >gi|20178288|sp|P00568.3|KAD1_HUMAN RecName: Full=Adenylate kinase isoenzyme 1; Short=AK 1; AltName: Full=ATP-AMP transphosphorylase 1; AltName: Full=Myokinase >gi|178322|gb|AAA51686.1| adenylate kinase [Homo sapiens] >gi|4996565|dbj|BAA78534.1| adenylate kinase 1 [Homo sapiens] >gi|49456909|emb|CAG46775.1| AK1 [Homo sapiens] >gi|49456961|emb|CAG46801.1| AK1 [Homo sapiens] >gi|54696030|gb|AAV38387.1| adenylate kinase 1 [Homo sapiens] >gi|71679687|gb|AAI00023.1| Adenylate kinase 1 [Homo sapiens] >gi|119608113|gb|EAW87707.1| adenylate kinase 1, isoform CRA_b [Homo sapiens] >gi|119608115|gb|EAW87709.1| adenylate kinase 1, isoform CRA_b [Homo sapiens] 100.00 9e-108 sp|P00568|KAD1_HUMAN Adenylate kinase isoenzyme 1 OS=Homo sapiens GN=AK1 PE=1 SV=3 100.00 8e-118 Q5T9B7 Q5T9B7_HUMAN Adenylate kinase 1 OS=Homo sapiens GN=AK1 PE=2 SV=1 YKL024c 168 5e-42 COG0563 Adenylate kinase and related kinases F Nucleotide transport and metabolism ; K00939|1|2e-110|398|cfa:480712|adenylate kinase [EC:2.7.4.3] GO:0007050//cell cycle arrest;GO:0046034//ATP metabolic process;GO:0009165//nucleotide biosynthetic process;GO:0016310//phosphorylation GO:0004017//adenylate kinase activity;GO:0005524//ATP binding GO:0005737//cytoplasm;GO:0005886//plasma membrane 116 tr|A0A024R1Y2|A0A024R1Y2_HUMAN ATP citrate lyase, isoform CRA_a OS=Homo sapiens GN=ACLY PE=4 SV=1 142815 MSAKAISEQTGKELLYKFICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQNLVVKPDQLIKRRGKLGLVGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHSQAEEFYVCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEILASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPPPFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNELANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRAIRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALGHRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQGKSTTLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILIPVFKNMADAMRKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTEEYKICRGIKEGRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSFDELGEIIQSVYEDLVANGVIVPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPNLILNVDGLIGVAFVDMLRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRHPWDDISYVLPEHMSM 255 6.4 2 13 13 6 6 0.557 0.414 0.520 8 8 7 * - * 0.497 0.0742226380560541 tr|A0A024R1Y2|A0A024R1Y2_HUMAN 100.00 1e-48 gi|194388336|dbj|BAG65552.1| unnamed protein product [Homo sapiens] 98.91 0.0 sp|P53396|ACLY_HUMAN ATP-citrate synthase OS=Homo sapiens GN=ACLY PE=1 SV=3 100.00 0.0 Q8N9C4 Q8N9C4_HUMAN cDNA FLJ37765 fis, clone BRHIP2024742, highly similar to ATP-CITRATE OS=Homo sapiens PE=2 SV=1 SPBC1703.07_1 524 3e-148 COG0074 Succinyl-CoA synthetase, alpha subunit C Energy production and conversion ; K01648|1|0.0|2189|hsa:47|ATP citrate (pro-S)-lyase [EC:2.3.3.8] GO:0031325//positive regulation of cellular metabolic process;GO:0006101//citrate metabolic process;GO:0015936//coenzyme A metabolic process;GO:0006112//energy reserve metabolic process;GO:0044262//cellular carbohydrate metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0006200//ATP catabolic process;GO:0006085//acetyl-CoA biosynthetic process GO:0048037//cofactor binding;GO:0005515//protein binding;GO:0003878//ATP citrate synthase activity;GO:0046872//metal ion binding;GO:0016829//lyase activity;GO:0005524//ATP binding;GO:0004775//succinate-CoA ligase (ADP-forming) activity GO:0005730//nucleolus;GO:0005829//cytosol;GO:0009346//citrate lyase complex;GO:0005886//plasma membrane;GO:0005739//mitochondrion 117 tr|Q53FB0|Q53FB0_HUMAN Chloride intracellular channel 1 variant (Fragment) OS=Homo sapiens PE=2 SV=1 33120 MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKYLKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK 584 39.4 1 28 28 7 7 0.753 0.508 0.661 14 17 15 * * * 0.640666666666667 0.12375917474407 tr|Q53FB0|Q53FB0_HUMAN 100.00 2e-139 gi|62898319|dbj|BAD97099.1| chloride intracellular channel 1 variant [Homo sapiens] 100.00 4e-60 sp|Q29238|CLIC1_PIG Chloride intracellular channel protein 1 (Fragment) OS=Sus scrofa GN=CLIC1 PE=3 SV=2 100.00 7e-139 Q53FB0 Q53FB0_HUMAN Chloride intracellular channel 1 variant (Fragment) OS=Homo sapiens PE=2 SV=1 - - - - - - - K05021|1|2e-139|494|ptr:462564|chloride intracellular channel 1 GO:0034765//regulation of ion transmembrane transport;GO:0045669//positive regulation of osteoblast differentiation;GO:0051881//regulation of mitochondrial membrane potential;GO:0006821//chloride transport;GO:0007165//signal transduction GO:0005247//voltage-gated chloride channel activity;GO:0005515//protein binding GO:0031965//nuclear membrane;GO:0005739//mitochondrion;GO:0005903//brush border;GO:0034707//chloride channel complex;GO:0005886//plasma membrane 118 tr|J3KQ18|J3KQ18_HUMAN D-dopachrome decarboxylase OS=Homo sapiens GN=DDT PE=1 SV=1 15819 MQLFLLAVSVPLPAMPFLELDTNLPANRVPAGLEKRLCAAAASILGKPADRVNVTVRPGLAMALSGSTEPCAQLSISSIGVVGTAEDNRSHSAHFFEFLTKELALGQDRILIRFFPLESWQIGKIGTVMTFL 154 19.7 1 8 8 2 2 0.753 0.710 0.731 7 7 7 * * * 0.731333333333333 0.0215019378971602 tr|J3KQ18|J3KQ18_HUMAN 100.00 1e-48 gi|119580026|gb|EAW59622.1| D-dopachrome tautomerase, isoform CRA_a [Homo sapiens] 100.00 6e-64 sp|P30046|DOPD_HUMAN D-dopachrome decarboxylase OS=Homo sapiens GN=DDT PE=1 SV=3 100.00 3e-12 H2PCJ8 H2PCJ8_PONAB Uncharacterized protein OS=Pongo abelii GN=DDT PE=4 SV=1 - - - - - - - K10028|1|5e-64|242|hsa:1652|D-dopachrome decarboxylase [EC:4.1.1.84] GO:0042438//melanin biosynthetic process GO:0004167//dopachrome isomerase activity;GO:0033981//D-dopachrome decarboxylase activity GO:0005737//cytoplasm 119 tr|Q6MZZ3|Q6MZZ3_HUMAN Putative uncharacterized protein DKFZp686I0746 OS=Homo sapiens GN=DKFZp686I0746 PE=2 SV=1 170495 MAQSKRHVYSRTPSGSRMSAEASARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLKREGTDTTAKTSKLRGLKPKKAPTARKTTTRRPKPTRPASTGVAGASSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMGVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEKFELSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEDCTMQLADHIKFTQSALDCMSVEVGRLRAFLQGGQEATDIALLLRDLETSCSDIRQFCKKIRRRMPGTDAPGIPAALAFGPQVSDTLLDCRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLLVAALEELAFKASEQIYGTPSSSPYECLRQSCNILISTMNKLATAMQEGEYDAERPPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKGFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGEEQQRGAIPGQAPGSVPGPGLVKDSPLLLQQISAMRLHISQLQHENSILKGAQMKASLASLPPLHVAKLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTHVVDITRTSPAAKSPSAQLMEQVAQLKSLSDTVEKLKDEVLKETVSQRPGATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGFGQRHRLVLTQEQLHQLHSRLIS 133 4.6 2 7 7 5 5 0.751 0.744 0.867 4 5 6 * * - 0.787333333333333 0.0690820767879291 tr|Q6MZZ3|Q6MZZ3_HUMAN 100.00 5e-47 gi|78100782|pdb|1TXQ|A Chain A, Crystal Structure Of The Eb1 C-Terminal Domain Complexed With The Cap-Gly Domain Of P150glued >gi|159794790|pdb|2HQH|A Chain A, Crystal Structure Of P150glued And Clip-170 >gi|159794791|pdb|2HQH|B Chain B, Crystal Structure Of P150glued And Clip-170 >gi|159794792|pdb|2HQH|C Chain C, Crystal Structure Of P150glued And Clip-170 >gi|159794793|pdb|2HQH|D Chain D, Crystal Structure Of P150glued And Clip-170 99.84 0.0 sp|Q14203|DCTN1_HUMAN Dynactin subunit 1 OS=Homo sapiens GN=DCTN1 PE=1 SV=3 100.00 0.0 Q6MZZ3 Q6MZZ3_HUMAN Putative uncharacterized protein DKFZp686I0746 OS=Homo sapiens GN=DKFZp686I0746 PE=2 SV=1 SPAC27D7.13c 79.0 5e-14 COG5244 Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B D Cell cycle control, cell division, chromosome partitioning ; K04648|1|0.0|2238|hsa:1639|dynactin 1 GO:0006810//transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007067//mitosis;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0008219//cell death;GO:0007399//nervous system development;GO:0000086//G2/M transition of mitotic cell cycle GO:0005515//protein binding;GO:0003774//motor activity GO:0005829//cytosol;GO:0005874//microtubule;GO:0031252//cell leading edge;GO:0000776//kinetochore;GO:0005813//centrosome;GO:0005868//cytoplasmic dynein complex;GO:0000922//spindle pole 120 tr|Q9HBP0|Q9HBP0_HUMAN Putative uncharacterized protein OS=Homo sapiens PE=2 SV=1 59174 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVIQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS 172 15.7 2 19 19 6 6 0.556 0.525 0.510 7 7 7 * * * 0.530333333333333 0.0234591844132172 tr|Q9HBP0|Q9HBP0_HUMAN 100.00 2e-71 gi|157461313|gb|ABV57182.1| inhibin alpha-subunit [Aonyx capensis] >gi|157461315|gb|ABV57183.1| inhibin alpha-subunit [Aonyx cinerea] >gi|157461317|gb|ABV57184.1| inhibin alpha-subunit [Enhydra lutris] >gi|157461319|gb|ABV57185.1| inhibin alpha-subunit [Lontra canadensis] >gi|157461321|gb|ABV57186.1| inhibin alpha-subunit [Lontra felina] >gi|157461323|gb|ABV57187.1| inhibin alpha-subunit [Lontra longicaudis] >gi|157461325|gb|ABV57188.1| inhibin alpha-subunit [Lutra lutra] >gi|157461329|gb|ABV57190.1| inhibin alpha-subunit [Pteronura brasiliensis] >gi|157461331|gb|ABV57191.1| inhibin alpha-subunit [Lutra sumatrana] >gi|157461333|gb|ABV57192.1| inhibin alpha-subunit [Lutrogale perspicillata] >gi|157461341|gb|ABV57196.1| inhibin alpha-subunit [Mustela erminea] >gi|157461345|gb|ABV57198.1| inhibin alpha-subunit [Mustela frenata] >gi|157461347|gb|ABV57199.1| inhibin alpha-subunit [Mustela lutreola] >gi|157461349|gb|ABV57200.1| inhibin alpha-subunit [Mustela nigripes] >gi|157461353|gb|ABV57202.1| inhibin alpha-subunit [Mustela putorius] >gi|157461355|gb|ABV57203.1| inhibin alpha-subunit [Mustela sibirica] >gi|157461357|gb|ABV57204.1| inhibin alpha-subunit [Mustela strigidorsa] >gi|157461359|gb|ABV57205.1| inhibin alpha-subunit [Neovison vison] >gi|157461363|gb|ABV57207.1| inhibin alpha-subunit [Martes flavigula] >gi|157461371|gb|ABV57211.1| inhibin alpha-subunit [Martes pennanti] >gi|157461379|gb|ABV57215.1| inhibin alpha-subunit [Ictonyx striatus] >gi|157461381|gb|ABV57216.1| inhibin alpha-subunit [Galictis vittata] >gi|157461383|gb|ABV57217.1| inhibin alpha-subunit [Galictis cuja] >gi|157461385|gb|ABV57218.1| inhibin alpha-subunit [Arctonyx collaris] >gi|157461387|gb|ABV57219.1| inhibin alpha-subunit [Meles meles] >gi|157461389|gb|ABV57220.1| inhibin alpha-subunit [Mellivora capensis] >gi|157461393|gb|ABV57222.1| inhibin alpha-subunit [Taxidea taxus] >gi|157461395|gb|ABV57223.1| inhibin alpha-subunit [Bassariscus astutus] 99.77 0.0 sp|P08476|INHBA_HUMAN Inhibin beta A chain OS=Homo sapiens GN=INHBA PE=1 SV=2 100.00 1e-67 Q6V1X6 Q6V1X6_CERNI Activin beta A peptide (Fragment) OS=Cervus nippon PE=3 SV=1 - - - - - - - K04667|1|0.0|814|pon:100439592|inhibin, beta GO:0032925//regulation of activin receptor signaling pathway;GO:0060279//positive regulation of ovulation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0045578//negative regulation of B cell differentiation;GO:0001541//ovarian follicle development;GO:0045650//negative regulation of macrophage differentiation;GO:0006952//defense response;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0048333//mesodermal cell differentiation;GO:0051799//negative regulation of hair follicle development;GO:0045077//negative regulation of interferon-gamma biosynthetic process;GO:0042476//odontogenesis;GO:0061029//eyelid development in camera-type eye;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042541//hemoglobin biosynthetic process;GO:0007399//nervous system development;GO:0046882//negative regulation of follicle-stimulating hormone secretion;GO:0007050//cell cycle arrest;GO:0042326//negative regulation of phosphorylation;GO:0008285//negative regulation of cell proliferation;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0045648//positive regulation of erythrocyte differentiation;GO:0008584//male gonad development;GO:0060021//palate development;GO:0030308//negative regulation of cell growth;GO:0042701//progesterone secretion;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006917//induction of apoptosis;GO:0071397//cellular response to cholesterol GO:0008083//growth factor activity;GO:0017046//peptide hormone binding;GO:0005125//cytokine activity;GO:0070699//type II activin receptor binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0005179//hormone activity GO:0043512//inhibin A complex;GO:0043509//activin A complex 121 tr|B4DW52|B4DW52_HUMAN cDNA FLJ55253, highly similar to Actin, cytoplasmic 1 OS=Homo sapiens PE=2 SV=1 44122 MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 2123 36.6 8 139 43 11 4 0.683 0.469 0.540 25 25 25 * - * 0.564 0.109 tr|B4DW52|B4DW52_HUMAN 100.00 0.0 gi|194376310|dbj|BAG62914.1| unnamed protein product [Homo sapiens] 92.53 0.0 sp|P60713|ACTB_SHEEP Actin, cytoplasmic 1 OS=Ovis aries GN=ACTB PE=2 SV=1 100.00 0.0 B4DW52 B4DW52_HUMAN Actin, cytoplasmic 1, N-terminally processed OS=Homo sapiens GN=ACTB PE=2 SV=1 SPBC32H8.12c 654 0.0 COG5277 Actin and related proteins Z Cytoskeleton ; K05692|1|0.0|719|mcc:713687|actin beta/gamma 1 GO:0007411//axon guidance;GO:0034332//adherens junction organization;GO:0006928//cellular component movement;GO:0051592//response to calcium ion;GO:0045214//sarcomere organization;GO:0034329//cell junction assembly;GO:0007596//blood coagulation;GO:0051086//chaperone mediated protein folding independent of cofactor GO:0019901//protein kinase binding;GO:0050998//nitric-oxide synthase binding;GO:0019894//kinesin binding;GO:0030957//Tat protein binding;GO:0042802//identical protein binding;GO:0005524//ATP binding;GO:0005200//structural constituent of cytoskeleton GO:0030863//cortical cytoskeleton;GO:0031941//filamentous actin;GO:0005829//cytosol;GO:0030016//myofibril;GO:0030424//axon;GO:0014069//postsynaptic density;GO:0070688//MLL5-L complex;GO:0035267//NuA4 histone acetyltransferase complex;GO:0030529//ribonucleoprotein complex 122 tr|H0Y8C6|H0Y8C6_HUMAN Importin-5 (Fragment) OS=Homo sapiens GN=IPO5 PE=1 SV=1 143267 XFRPLLPRRLAPVTSPPPLAPTCGRSRRAPVQETYENIPGQSKITFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNLIDEDGNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAAMLRKHTNIVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVPLLKFYFHDGVRVAAAESMPLLLECARVRGPEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQWGLCIFDDVIEHCSPASFKYAEYFLRPMLQYVCDNSPEVRQAAAYGLGVMAQYGGDNYRPFCTEALPLLVRVIQSADSKTKENVNATENCISAVGKIMKFKPDCVNVEEVLPHWLSWLPLHEDKEEAVQTFNYLCDLIESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQAAIQELLNSA 324 10.6 1 15 15 9 9 0.732 0.557 0.752 9 10 10 * * * 0.680333333333333 0.107276900278361 tr|H0Y8C6|H0Y8C6_HUMAN 100.00 0.0 gi|332841543|ref|XP_001140931.2| PREDICTED: importin-5 [Pan troglodytes] >gi|194380888|dbj|BAG64012.1| unnamed protein product [Homo sapiens] 99.63 0.0 sp|O00410|IPO5_HUMAN Importin-5 OS=Homo sapiens GN=IPO5 PE=1 SV=4 100.00 0.0 Q9BVS9 Q9BVS9_HUMAN IPO5 protein (Fragment) OS=Homo sapiens GN=IPO5 PE=2 SV=1 SPAC1B1.03c 60.1 2e-08 COG5215 Karyopherin (importin) beta U Intracellular trafficking, secretion, and vesicular transport ; K14293|1|2e-06|55.8|bmy:Bm1_57540|importin subunit beta-1 GO:0006607//NLS-bearing substrate import into nucleus;GO:0019048//virus-host interaction;GO:0006610//ribosomal protein import into nucleus GO:0008565//protein transporter activity;GO:0008536//Ran GTPase binding;GO:0005095//GTPase inhibitor activity GO:0005730//nucleolus;GO:0005643//nuclear pore;GO:0005737//cytoplasm 123 tr|A4D1W8|A4D1W8_HUMAN Ependymin related protein 1 (Zebrafish), isoform CRA_b OS=Homo sapiens GN=UCC1 PE=4 SV=1 42233 MPPRMLVAPLPLHFLLAAVSSENRSGRRQWQQAVAAGSGPGRNSSRAIHWSLPRALVPATGTRASGSQKRQRPPKGQEALWSRPHSRHSAERAGGSHSDPGRLSAPLGLGLPSGRGRLTAMPGRAPLRTVPGALGAWLLGGLWAWTLCGLCSLGAVGAPRPCQAPQQWEGRQVMYQQSSGRNSRALLSYDGLNQRVRVLDERKALIPCKRLFEYILLYKDGVMFQIDQATKQCSKMTLTQPWDPLDIPQNSTFEDQYSIGGPQEQITVQEWSDRKSARSYETWIGIYTVKDCYPVQETFTINYSVILSTRFFDIQLGIKDPSVFTPPSTCQMAQLEKMSEDCSW 172 15.4 2 12 12 5 5 0.548 0.608 0.879 6 5 6 * * - 0.678333333333333 0.176352865962913 tr|A4D1W8|A4D1W8_HUMAN 100.00 4e-30 gi|345110633|ref|NP_001229875.2| mammalian ependymin-related protein 1 isoform 2 precursor [Homo sapiens] >gi|115111027|gb|ABI84106.1| mammalian ependymin protein 1a [Homo sapiens] 100.00 9e-116 sp|Q9UM22|EPDR1_HUMAN Mammalian ependymin-related protein 1 OS=Homo sapiens GN=EPDR1 PE=1 SV=2 100.00 7e-75 C9JYS3 C9JYS3_HUMAN Mammalian ependymin-related protein 1 OS=Homo sapiens GN=EPDR1 PE=4 SV=1 - - - - - - - - GO:0007160//cell-matrix adhesion GO:0005509//calcium ion binding GO:0005576//extracellular region;GO:0005764//lysosome 124 sp|Q7Z7M9|GALT5_HUMAN Polypeptide N-acetylgalactosaminyltransferase 5 OS=Homo sapiens GN=GALNT5 PE=1 SV=1 132304 MNRIRKFFRGSGRVLAFIFVASVIWLLFDMAALRLSFSEINTRVIKEDIVRRERIGFRVQPDQGKIFYSSIKEMKPPLRGHGKGAWGKENVRKTEESVLKVEVDLDQTQRERKMQNALGRGKVVPLWHPAHLQTLPVTPNKQKTDGRGTKPEASSHQGTPKQTTAQGAPKTSFIAAKGTQVVKISVHMGRVSLKQEPRKSHSPSSDTSKLAAERDLNVTISLSTDRPKQRSQAVANERAHPASTAVPKSGEAMALNKTKTQSKEVNANKHKANTSLPFPKFTVNSNRLRKQSINETPLGSLSKDDGARGAHGKKLNFSESHLVIITKEEEQKADPKEVSNSKTKTIFPKVLGKSQSKHISRNRSEMSSSSLAPHRVPLSQTNHALTGGLEPAKINITAKAPSTEYNQSHIKALLPEDSGTHQVLRIDVTLSPRDPKAPGQFGRPVVVPHGKEKEAERRWKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHNNLPTTSVIMCFVDEVWSTLLRSVHSVINRSPPHLIKEILLVDDFSTKDYLKDNLDKYMSQFPKVRILRLKERHGLIRARLAGAQNATGDVLTFLDSHVECNVGWLEPLLERVYLSRKKVACPVIEVINDKDMSYMTVDNFQRGIFVWPMNFGWRTIPPDVIAKNRIKETDTIRCPVMAGGLFSIDKSYFFELGTYDPGLDVWGGENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMKTVERNLVRVAEVWLDEYKELFYGHGDHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLENVFPDLRAPIVRASGVLINVALGKCISIENTTVILEDCDGSKELQQFNYTWLRLIKCGEWCIAPIPDKGAVRLHPCDNRNKGLKWLHKSTSVFHPELVNHIVFENNQQLLCLEGNFSQKILKVAACDPVKPYQKWKFEKYYEA 248 5.7 - 11 11 5 5 0.863 0.556 0.632 6 6 6 - * * 0.683666666666667 0.159888502817849 sp|Q7Z7M9|GALT5_HUMAN 100.00 0.0 gi|6688167|emb|CAB65104.1| GalNAc-T5 [Homo sapiens] 100.00 0.0 sp|Q7Z7M9|GALT5_HUMAN Polypeptide N-acetylgalactosaminyltransferase 5 OS=Homo sapiens GN=GALNT5 PE=1 SV=1 100.00 0.0 A5PKZ1 A5PKZ1_HUMAN UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) OS=Homo sapiens GN=GALNT5 PE=2 SV=1 - - - - - - - K00710|1|0.0|1929|hsa:11227|polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0006024//glycosaminoglycan biosynthetic process GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0030246//carbohydrate binding GO:0000139//Golgi membrane;GO:0016021//integral to membrane 125 tr|H0Y7A7|H0Y7A7_HUMAN Calmodulin (Fragment) OS=Homo sapiens GN=CALM2 PE=1 SV=1 24209 SPSGESELSGCVVASRKPVALAAWLALYIASHFAQQPCKADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 201 9.1 9 15 15 2 2 0.653 0.603 0.592 8 8 8 * - * 0.616 0.0325115364140177 tr|H0Y7A7|H0Y7A7_HUMAN 100.00 2e-74 gi|225705998|gb|ACO08845.1| Calmodulin-alpha [Osmerus mordax] 100.00 5e-81 sp|P62149|CALM_CHICK Calmodulin OS=Gallus gallus GN=CALM PE=1 SV=2 100.00 1e-79 H0WZA4 H0WZA4_OTOGA Uncharacterized protein OS=Otolemur garnettii GN=CALM1 PE=4 SV=1 SPAC3A12.14 235 4e-62 COG5126 Ca2+-binding protein (EF-Hand superfamily) TZDR Signal transduction mechanisms ; Cytoskeleton ; Cell cycle control, cell division, chromosome partitioning ; General function prediction only ; K02183|1|3e-82|304|ecb:100071150|calmodulin GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0006006//glucose metabolic process;GO:0050804//regulation of synaptic transmission;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006470//protein dephosphorylation;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0030168//platelet activation;GO:0007202//activation of phospholipase C activity;GO:0051592//response to calcium ion;GO:0032465//regulation of cytokinesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0044281//small molecule metabolic process;GO:0006936//muscle contraction;GO:0048741//skeletal muscle fiber development;GO:0002576//platelet degranulation;GO:0006606//protein import into nucleus;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0046209//nitric oxide metabolic process;GO:0014883//transition between fast and slow fiber;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0033173//calcineurin-NFAT signaling cascade;GO:0005980//glycogen catabolic process;GO:0050999//regulation of nitric-oxide synthase activity;GO:0008543//fibroblast growth factor receptor signaling pathway GO:0043548//phosphatidylinositol 3-kinase binding;GO:0031997//N-terminal myristoylation domain binding;GO:0019904//protein domain specific binding;GO:0031432//titin binding;GO:0048306//calcium-dependent protein binding;GO:0031996//thioesterase binding;GO:0043274//phospholipase binding;GO:0005516//calmodulin binding;GO:0033192//calmodulin-dependent protein phosphatase activity;GO:0005509//calcium ion binding GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005955//calcineurin complex;GO:0005876//spindle microtubule;GO:0005886//plasma membrane;GO:0000922//spindle pole;GO:0005739//mitochondrion;GO:0030018//Z disc;GO:0005813//centrosome;GO:0005576//extracellular region