Specific Human and Candida Cellular Interactions Lead to Controlled or Persistent Infection Outcomes during Granuloma-Like Formation

Supplemental material

  • Supplemental file 1 -

    Fig. S1. Evolution profiles of the fungal burden within granulomatous structures of Candida spp. Fig. S2. Evolution of the fungal burden within granulomatous structures of 32 clinical isolates of Candida spp. Fig. S3. Evolution of the fungal burden within granulomatous structures of 32 clinical isolates of Candida spp. Table S1. Distribution of granulocyte, monocyte, and T cell subsets based on CD66, CD14, CD56, CD4, and CD8 from persistent-infection and controlled-infection granulomas after infection with C. albicans, C. dubliniensis, and C. tropicalis (group A). Table S2. Distribution of granulocyte, monocyte, and T cell subsets based on CD66, CD14, CD56, CD4, and CD8 from persistent-infection and controlled-infection granulomas after infection with C. lusitaniae, C. parapsilosis, and C. glabrata (group B). Table S3. Distribution of granulocyte, monocyte, and T cell subsets based on CD66, CD14, CD56, CD4, and CD8 from persistent-infection and controlled-infection granulomas after infection with C. krusei and C. kefyr (group C).

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  • Supplemental file 2 -

    Video S1. Representative movie from microscopy time-lapse series.

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  • Supplemental file 3 -

    Video S2. Representative movie from microscopy time-lapse series showing human leucocyte infected by GFP-tagged C. albicans blastoconidia (MOI of 2,000∶1).

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  • Supplemental file 4 -

    Video S1 and S2 legends.

    PDF, 57K