The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and FEN1-Mediated Flap Cleavage during Polymerase δ Elongation

Supplemental material

• Supplemental file 1 -

  Fig. S1 (Purified proteins), S2 (Templates used in polymerase extension assays), S3 (Functional and structural domains required to promote polymerization), S4 (Telomeric G-rich substrate formation of G4 DNA structures), S5 (Strand displacement assays using 12-nt or 36-nt gap substrates), S6 (WRN-promoted FEN1 cleavage during strand displacement synthesis), S7 (FEN1-E359K binding to WRN), S8 (Southern blot analysis), S9 (Distribution of TRF lengths), and S10 (Simplified replication fork) and Table S1 (Oligonucleotides)

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