Myofibrillar Z-discs Are a Protein Phosphorylation Hot Spot with Protein Kinase C (PKCα) Modulating Protein Dynamics

Supplemental Data

• Supplemental Figures (.pdf, 8.1 MB) - Supplemantal Figures S1-8
• Supplemental Table ledgends (.pdf, 71 KB) - Supplemental Table ledgends S1-10
• Supplemental Table 1 (.xlsx, 1.5 MB) - Quantitative myogenesis dataset
• Supplemental Table 2 (.xlsx, 458 KB) - Result files from GO enrichment analysis of the 11 cluster of the C2C12 myogenesis proteome
• Supplemental Table 3 (.xlsx, 146 KB) - Result files from GO enrichment analysis of the 4 main cluster of the C2C12 myogenesis proteome
• Supplemental Table 4 (.xlsx, 11.5 MB) - Proteome dataset
• Supplemental Table 5 (.xlsx, 2.4 MB) - Global phosphoproteome dataset
• Supplemental Table 6 (.xlsx, 2.0 MB) - Result files from GO enrichment analysis of the C2C12 proteome and phosphoproteome dataset
• Supplemental Table 7 (.pdf, 196 KB) - The Z-disc protein compendium
• Supplemental Table 8 (.xlsx, 82 KB) - Quantitative MS data from in vitro kinase assays using protein kinase C and mouse/human filamin C d23-24 wildtype and phosphosite mutants
• Supplemental Table 9 (.xlsx, 17 KB) - In silico calpainolysis data
• Supplemental Table 10 (.xlsx, 142 KB) - Top-down MS data from in vitro calpainolysis assays
• Supplemantal Movie 1 (.avi, 272.9 MB) - Electrical pulse stimulated, contracting C2C12 myotubes
• Original data (.pdf, 71 KB) - Original data of Western blot analyses