Table S5 Gene Ontology analyses for elevated peaks in cnc1_jdh2_ yeast mutants. ,,,,, GO-BP,,,,, Term,p-value,Genes in Term,Target Genes in Term,Fraction of Targets in Term,Gene Symbols carbohydrate biosynthetic process,3.20E-07,73,24,3.80%,"FBA1,ENO2,MDH2,GSY2,BUD7,PYC2,TDH3,GSY1,CHS7,KRE6,ENO1,TPS3,INO1,IGD1,PYC1,GLC3,YMR084W,GDB1,FKS1,TDH1,TSL1,PGM2,ROT2,PGI1" monocarboxylic acid metabolic process,6.90E-06,156,36,5.60%,"ACS1,FBA1,CIT2,ENO2,FOX2,SUR2,POX1,ISA1,CDC19,NDE2,NDE1,ACH1,MAE1,EEB1,TDH1,YER010C,GLO1,CRC1,TDA9,SPS19,BIO5,UGA2,PYC2,PFK2,TDH3,GOR1,FAS2,ENO1,ICL2,OAR1,ALD4,PYC1,HST4,HXK1,PGI1,CYB2" pyruvate metabolic process,1.20E-05,41,15,2.30%,"ALD4,FBA1,ENO2,PYC1,MAE1,PYC2,PFK2,TDH1,TDH3,HXK1,PGI1,ENO1,CDC19,NDE2,NDE1" gluconeogenesis,3.90E-05,18,9,1.40%,"FBA1,ENO2,PYC1,MDH2,PYC2,TDH1,TDH3,PGI1,ENO1" carboxylic acid metabolic process,4.70E-05,416,71,11.10%,"ACS1,ENO2,MST1,ARG4,POX1,NDE1,YLR126C,MET17,MET6,ACH1,MAE1,MET30,TDH1,MSR1,ARG2,SPS19,BIO5,UGA2,PYC2,SNO3,PFK2,URA8,GLY1,ALD4,OAR1,PYC1,MET7,HST4,HXK1,SDH1,PGI1,ALT2,CYB2,YGP1,LAP3,ACO1,YGR012W,FBA1,PLB3,FOX2,CIT2,SUR2,ISA1,CDC19,NDE2,EEB1,YMR084W,YER010C,GLO1,TDA9,CRC1,AAT2,MDH2,TDH3,GAD1,GRS2,GOR1,FRS2,ADE3,FAS2,ENO1,ICL2,CTR86,UTR4,GLN1,SHM2,PUT1,CPA1,YDR341C,ARG3,TRP1" cellular response to abiotic stimulus,5.00E-05,61,18,2.80%,"HOG1,SSK22,GRE3,MNN4,HSP12,SLN1,STF2,PBS2,RIM101,YPD1,RIM11,CTT1,SKO1,MSB2,RSP5,WAR1,FRT2,NRG1" oxoacid metabolic process,5.10E-05,432,73,11.40%,"ACS1,ENO2,MST1,ARG4,POX1,NDE1,YLR126C,MET17,MET6,ACH1,MAE1,MET30,TDH1,MSR1,ARG2,SPS19,BIO5,UGA2,PYC2,SNO3,PFK2,URA8,GLY1,ALD4,OAR1,PYC1,MET7,HST4,HXK1,SDH1,PGI1,ALT2,CYB2,YGP1,LAP3,ACO1,YGR012W,FBA1,CIT2,PLB3,FOX2,SUR2,ISA1,CDC19,NDE2,EEB1,YMR084W,URE2,YER010C,GLO1,TDA9,CRC1,AAT2,MDH2,TDH3,GAD1,ADE3,PPX1,GRS2,GOR1,FRS2,FAS2,ENO1,ICL2,CTR86,UTR4,GLN1,SHM2,PUT1,CPA1,YDR341C,ARG3,TRP1" response to abiotic stimulus,5.80E-05,171,36,5.60%,"ENA1,GRE3,MNN4,HSP12,CUR1,STF2,RAD57,MYO3,UBC5,SPI1,CTT1,UPC2,WSC2,SKO1,RSP5,WAR1,NRG1,FRT2,SSK22,HOG1,SPT23,SLN1,NUP100,PBS2,RIM101,RRD1,SIN3,CIN5,RIM15,NHA1,YPD1,SLT2,DDR2,RIM11,HSP104,MSB2" organic acid metabolic process,6.00E-05,434,73,11.40%,"ACS1,ENO2,MST1,ARG4,POX1,NDE1,YLR126C,MET17,MET6,ACH1,MAE1,MET30,TDH1,MSR1,ARG2,SPS19,BIO5,UGA2,PYC2,SNO3,PFK2,URA8,GLY1,ALD4,OAR1,PYC1,MET7,HST4,HXK1,SDH1,PGI1,ALT2,CYB2,YGP1,LAP3,ACO1,YGR012W,FBA1,CIT2,PLB3,FOX2,SUR2,ISA1,CDC19,NDE2,EEB1,YMR084W,URE2,YER010C,GLO1,TDA9,CRC1,AAT2,MDH2,TDH3,GAD1,ADE3,PPX1,GRS2,GOR1,FRS2,FAS2,ENO1,ICL2,CTR86,UTR4,GLN1,SHM2,PUT1,CPA1,YDR341C,ARG3,TRP1" monosaccharide biosynthetic process,6.70E-05,19,9,1.40%,"FBA1,ENO2,PYC1,MDH2,PYC2,TDH1,TDH3,PGI1,ENO1" glucose metabolic process,8.00E-05,42,14,2.20%,"PKP1,FBA1,ENO2,PYC1,MDH2,PYC2,TDH1,TDH3,HXK1,PGM2,ENO1,PGI1,NDE2,NDE1" negative regulation of filamentous growth of a population of unicellular organisms,1.60E-04,13,7,1.10%,"IME4,DIG1,DIG2,FKH2,SIP4,SUT1,NRG1" cellular response to osmotic stress,1.80E-04,45,14,2.20%,"HOG1,SSK22,YPD1,GRE3,RIM11,MNN4,CTT1,HSP12,SLN1,MSB2,SKO1,PBS2,NRG1,FRT2" hexose metabolic process,3.10E-04,58,16,2.50%,"PKP1,FBA1,ENO2,GRE3,MDH2,PYC2,TDH3,ENO1,AMS1,NDE2,NDE1,PYC1,HXK1,TDH1,PGM2,PGI1" cellular carbohydrate biosynthetic process,3.50E-04,53,15,2.30%,"IGD1,INO1,GLC3,GDB1,YMR084W,BUD7,GSY2,FKS1,GSY1,TSL1,CHS7,ROT2,PGM2,KRE6,TPS3" carbohydrate metabolic process,3.80E-04,316,54,8.50%,"GAS5,CIT2,FBA1,ENO2,GRE3,GSY2,OCH1,MNN4,MNL1,CHS7,CDC19,AMS1,NDE2,NDE1,UTH1,INO1,PMI40,YMR084W,TDH1,GDA1,TSL1,CAT8,PGM2,ROT2,PKP1,YMR196W,MDH2,PYC2,NQM1,BUD7,PFK2,TDH3,SOL1,STT3,GSY1,KRE6,ENO1,EXG1,ICL2,CRH1,TPS3,IGD1,PYC1,GLC3,GDB1,FKS1,HSP104,GAS3,HXK1,PGU1,MNN1,PGI1,PPG1,SNF2" ADP metabolic process,4.60E-04,33,11,1.70%,"FBA1,ENO2,PFK2,TDH1,TDH3,HXK1,PGI1,ENO1,CDC19,NDE2,NDE1" vitamin transport,6.30E-04,8,5,0.80%,"THI7,THI72,MCH5,TPN1,BIO5" polysaccharide metabolic process,7.20E-04,74,18,2.80%,"GAS5,GSY2,BUD7,GSY1,CHS7,KRE6,EXG1,CRH1,UTH1,IGD1,GLC3,YMR084W,GDB1,FKS1,PGU1,PGM2,ROT2,PPG1" GO-MF,,,,, catalytic activity,1.10E-05,2392,257,49.50%,"PRB1,ARP8,ECO1,ARG4,POX1,AAD4,ECM4,SIP1,RAS1,INO1,RAD30,DGK1,CTT1,HSP150,NQM1,CST9,CST26,HPF1,PPH3,IME4,EFM6,SAT4,SSL1,ECM16,HXK1,SDH1,RRP3,RAD54,IPT1,YGR012W,ENA1,GPI2,NDE2,LPX1,UBC5,TEF4,TRR2,PGM2,ROT2,PTP1,ATF2,KRE6,EXG1,FAS2,MKK1,FUN19,PBI1,HSP104,TOP1,RMD5,YJL213W,TUB4,CLP1,ACS1,OCH1,YAK1,MEF1,TEF1,TUB2,AMS1,AKR2,QCR10,YPS6,MET6,PMI40,ACH1,CPR4,RPT4,MSR1,RAT1,RSP5,HEM15,KIN82,CRH1,PBY1,OCA2,OAR1,CMK1,HST4,YSH1,SEN34,THI21,GPI13,ACO1,CIT2,GSY2,YOL057W,PMC1,APE1,PHO3,NOG2,POT1,CSH1,RCK1,YER010C,TSL1,LOT6,ACC1,RCL1,MNN9,TCD2,SOL1,GOR1,PPX1,GLO2,YMR210W,ICL2,PLB1,GLN1,SKM1,YLL066C,GTO1,PRI2,MNN1,BDH1,CPA1,OYE2,SIA1,FRE7,RAD57,MCR1,NDE1,YLR126C,DBP7,SAP4,NGL3,PSH1,KSS1,PLB2,DCS2,ADH5,PYC2,TPK3,SNO3,URA8,GSY1,UBP5,ATP2,TDA3,TPS3,VHS1,SMK1,YPD1,PYC1,FKS1,HEM4,PGU1,ADE17,ALT2,PTP3,BPT1,NSE1,PLB3,FBA1,PCA1,RAD2,DIA3,LCB2,DUG3,UTH1,YMR084W,GLO1,YNL200C,AAT2,MDL2,STE14,RKM2,CAT5,ENO1,UTR4,RDH54,CFD1,DLD2,GDB1,RIB7,GAS3,PDI1,PUT1,TRA1,SNF2,TUB1,GTT1,MYO4,SIP2,HEF3,MST1,TKL2,YDL057W,MET17,AYR1,YPT53,EPL1,INP52,TDH1,ARA2,YME1,POL12,FMP46,ARG2,SPS19,UGA2,TOP3,IMA3,HOG1,SMC6,DSS1,RKM5,YML002W,GUD1,EUG1,RIM15,DBP3,SWE1,HOS1,PGI1,YHR112C,FOX2,TDA1,GRE3,SUR2,MNL1,AFG3,MCM3,MYO3,XKS1,NOB1,DBP1,YCK1,URE2,DNF1,ECM3,PTC6,YMR196W,PKP1,YNL181W,DPB2,RAD23,SLN1,GAD1,PMA1,DBR1,YLR446W,GLC3,HSL1,NCS6,YLR177W,THI22,AUR1,SNQ2,COQ6,RIM11,YMR027W,SAM4,KIP1,YDR341C,ARG3,CPT1" secondary active transmembrane transporter activity,2.80E-04,113,22,4.20%,"YGR125W,JEN1,GAP1,VHC1,TPO4,YBR241C,RGT2,SAL1,UGA4,YMD8,OPT1,YDL199C,AGP1,HXT13,AGP2,AGP3,CRC1,HXT17,SUL2,BIO5,HXT7,ITR1" active transmembrane transporter activity,5.10E-04,190,31,6.00%,"YGR125W,ENA1,JEN1,MDL2,PCA1,PMC1,GAP1,VHC1,TPO4,YBR241C,ATP2,RGT2,SAL1,PMA1,UGA4,YMD8,OPT1,YDL199C,SNQ2,DNF1,AGP1,AGP2,BPT1,HXT13,AGP3,CRC1,SUL2,HXT17,BIO5,HXT7,ITR1" "hydrolase activity, hydrolyzing O-glycosyl compounds",5.70E-04,47,12,2.30%,"YMR196W,IMA3,GLC3,GDB1,MNL1,PGU1,ROT2,KRE6,EXG1,HPF1,CRH1,AMS1" GO-CC,,,,, cell periphery,9.30E-08,715,103,19.80%,"JEN1,CIS3,SIP2,FMP45,UBX2,HSP12,PEA2,FLO5,TPO4,NIS1,RGT2,FRE7,ATO3,RAS1,PIR1,MET17,YPS6,MET6,CDC25,YPT53,AQY1,YNL194C,SPI1,PLB2,INP52,TDH1,MSB4,WSC2,RSP5,AGP3,YHR214W,HXT17,BIO5,HSP150,YGL082W,PUN1,ZRT1,KIN82,GAP1,VHC1,YBR241C,SNG1,HPF1,CRH1,BUD3,TOS6,YDL199C,FKS1,ADE17,PGI1,ENA1,MSC1,YGR125W,PLB3,PCA1,MCH5,PMC1,CAP2,FAT3,THI7,DIA3,MYO3,UGA4,PAL1,UTH1,YCK1,DNF1,AGP1,AGP2,YAP1801,SUL2,ITR1,CWP1,TEA1,SLN1,OSH2,MDM12,PPX1,KRE6,EXG1,ENO1,FET4,LAS17,PLB1,PMA1,FLO10,PNS1,OPT1,HSL1,SNQ2,TCB3,SKM1,GAS3,SVS1,SRV2,YSC84,HXT13,RIM8,MSC3,SEC3,GTT1,AQR1,HXT7" plasma membrane,3.80E-07,518,79,15.20%,"JEN1,CIS3,SIP2,FMP45,UBX2,HSP12,TPO4,RGT2,FRE7,ATO3,RAS1,MET17,MET6,YPS6,AQY1,CDC25,YPT53,YNL194C,TDH1,WSC2,RSP5,AGP3,YHR214W,HXT17,BIO5,YGL082W,PUN1,ZRT1,KIN82,GAP1,VHC1,YBR241C,SNG1,FKS1,YDL199C,PGI1,ADE17,MSC1,ENA1,YGR125W,PLB3,PCA1,MCH5,PMC1,CAP2,FAT3,THI7,UGA4,PAL1,YCK1,DNF1,AGP1,AGP2,YAP1801,SUL2,ITR1,SLN1,OSH2,MDM12,KRE6,PPX1,ENO1,FET4,PLB1,PMA1,OPT1,PNS1,SNQ2,TCB3,SKM1,GAS3,YSC84,HXT13,MSC3,RIM8,SEC3,GTT1,HXT7,AQR1" integral component of plasma membrane,6.30E-07,117,28,5.40%,"YGR125W,ENA1,JEN1,PCA1,ZRT1,UBX2,PMC1,GAP1,SLN1,VHC1,YBR241C,FET4,RGT2,PMA1,UGA4,PNS1,OPT1,AQY1,YDL199C,AGP1,HXT13,AGP2,AGP3,SUL2,HXT17,BIO5,ITR1,HXT7" replication fork,6.60E-04,61,14,2.70%,"DPB11,PRP46,POB3,ECO1,RAD30,CTF18,DPB2,MRC1,TOP1,PRI2,POL12,MCM3,HHF1,RAD57" "Gene ontologies were determined by HOMER. Lists display non-redundant highly enriched biological processes, molecular function, and cellular component (p<10-4).",,,,,