Supplementary table 4: transcription factor binding sites enriched in the gene-module regulated by f13 rule	
Transcription factor binding sites	q values
Arnt-MA0004.1	1.66E-05
Arnt::Ahr-MA0006.1	3.55E-07
En1-MA0027.1	3.84E-07
ELK1-MA0028.1	1.33E-06
FOXD1-MA0031.1	5.63E-05
FOXC1-MA0032.1	3.33E-16
FOXL1-MA0033.1	4.44E-16
Gfi1-MA0038.1	7.70E-11
FOXI1-MA0042.1	2.89E-07
NHLH1-MA0048.1	0.002562332
MZF1_1-4-MA0056.1	3.33E-16
MZF1_5-13-MA0057.1	4.43E-16
Nkx2-5-MA0063.1	6.02E-16
Pax2-MA0067.1	3.33E-16
RORA_1-MA0071.1	0.000107795
Prrx2-MA0075.1	5.13E-05
SOX9-MA0077.1	8.43E-05
Sox17-MA0078.1	6.44E-10
SPIB-MA0081.1	3.87E-16
SRY-MA0084.1	1.18E-05
Sox5-MA0087.1	2.22E-12
TEAD1-MA0090.1	0.015304444
Hand1::Tcfe2a-MA0092.1	1.56E-07
REL-MA0101.1	0.000384473
Zfp423-MA0116.1	0.034067906
Mafb-MA0117.1	2.92E-15
Nkx3-2-MA0122.1	3.31E-15
NKX3-1-MA0124.1	2.65E-06
Nobox-MA0125.1	1.06E-05
ZNF354C-MA0130.1	3.33E-16
Pdx1-MA0132.1	3.90E-13
BRCA1-MA0133.1	3.33E-16
ELF5-MA0136.1	1.24E-15
CTCF-MA0139.1	0.006688849
Klf4-MA0039.2	2.79E-15
RUNX1-MA0002.2	0.000107795
Foxa2-MA0047.2	0.010227699
ARID3A-MA0151.1	2.14E-13
INSM1-MA0155.1	0.001779375
NFIC-MA0161.1	3.33E-16
Nr2e3-MA0164.1	7.83E-06
Esrrb-MA0141.2	0.000380906
Zfx-MA0146.2	9.76E-09
Atoh1-MA0461.1	8.31E-14
BATF::JUN-MA0462.1	0.001640098
Bhlhe40-MA0464.1	2.08E-07
CDX2-MA0465.1	0.021411065
DUX4-MA0468.1	0.006720689
E2F3-MA0469.1	0.000121213
E2F4-MA0470.1	2.66E-05
E2F6-MA0471.1	8.53E-10
EGR2-MA0472.1	6.36E-09
Erg-MA0474.1	0.003138083
FOS-MA0476.1	4.88E-12
FOSL1-MA0477.1	3.87E-08
FOSL2-MA0478.1	1.66E-05
FOXH1-MA0479.1	0.010855784
Gata4-MA0482.1	0.000836599
JUN (var.2)-MA0489.1	0.006873165
JUNB-MA0490.1	1.44E-07
JUND-MA0491.1	1.95E-08
Klf1-MA0493.1	1.71E-10
Myod1-MA0499.1	5.59E-14
Myog-MA0500.1	2.61E-14
NFYB-MA0502.1	0.015304444
Nr5a2-MA0505.1	0.036630392
Rfx1-MA0509.1	2.70E-05
RUNX2-MA0511.1	0.014212906
Rxra-MA0512.1	8.97E-05
Sox3-MA0514.1	1.55E-06
Sox6-MA0515.1	1.11E-06
SP2-MA0516.1	1.53E-11
Stat5a::Stat5b-MA0519.1	0.030211709
Tcf12-MA0521.1	4.74E-13
Tcf3-MA0522.1	1.14E-16
TCF7L2-MA0523.1	0.027656021
TFAP2C-MA0524.1	1.32E-09
USF2-MA0526.1	0.045738942
AR-MA0007.2	0.019359773
E2F1-MA0024.2	5.92E-10
EBF1-MA0154.2	3.83E-13
EGR1-MA0162.2	3.26E-12
ESR2-MA0258.2	0.035981575
FOXA1-MA0148.3	0.010855784
Gata1-MA0035.3	0.00184028
GATA2-MA0036.2	0.026196068
GATA3-MA0037.2	8.32E-08
HNF4A-MA0114.2	0.003997362
MAX-MA0058.2	0.040552105
Myb-MA0100.2	0.035717007
Myc-MA0147.2	3.54E-08
Mycn-MA0104.3	1.49E-11
NFKB1-MA0105.3	0.003139141
Sox2-MA0143.3	2.50E-13
SP1-MA0079.3	9.60E-15
STAT3-MA0144.2	0.035359188
TFAP2A-MA0003.2	0.021316937
ZEB1-MA0103.2	2.14E-13
ESRRA-MA0592.1	0.020109637
FOXP2-MA0593.1	0.041939136
SREBF1-MA0595.1	8.27E-07
THAP1-MA0597.1	1.36E-15
EHF-MA0598.1	3.33E-16
KLF5-MA0599.1	1.72E-17
RFX2-MA0600.1	0.001285199
TFAP2A-MA0003.1	4.43E-16
E2F1-MA0024.1	4.02E-05
GATA2-MA0036.1	3.33E-16
GATA3-MA0037.1	3.33E-16
Gfi-MA0038.1	7.70E-11
MEF2A-MA0052.1	0.01017559
Myf-MA0055.1	1.88E-09
MAX-MA0058.1	0.007664977
NFYA-MA0060.1	0.015681506
NF-kappaB-MA0061.1	5.10E-05
USF1-MA0093.1	3.90E-13
YY1-MA0095.1	3.33E-16
ETS1-MA0098.1	3.33E-16
Myb-MA0100.1	1.32E-09
NFKB1-MA0105.1	0.001570489
Tal1::Gata1-MA0140.1	0.000585564
Esrrb-MA0141.1	0.000185171
Stat3-MA0144.1	0.01029179
Zfx-MA0146.1	2.50E-08
FOXA1-MA0148.1	2.14E-05
Gata1-MA0035.2	4.96E-05
STAT1-MA0137.2	0.011025451
Mycn-MA0104.2	0.017214008
NFATC2-MA0152.1	2.66E-15
EBF1-MA0154.1	6.51E-11
FEV-MA0156.1	5.59E-14
FOXO3-MA0157.1	2.65E-06
HOXA5-MA0158.1	5.13E-11
NR4A2-MA0160.1	6.43E-09
Egr1-MA0162.1	1.52E-05
SPI1-MA0080.2	6.69E-16
CREB1-MA0018.2	0.000109181
AP1-MA0099.2	1.30E-14
SP1-MA0079.2	9.64E-18
HIF1A::ARNT-MA0259.1	1.04E-09
SOX10-MA0442.1	3.33E-16