Supplementary table 6: transcription factor binding sites enriched in the gene-module regulated by f12 rule Transcription factor binding sites q values En1-MA0027.1 0.01513107 FOXC1-MA0032.1 0.01513107 FOXL1-MA0033.1 0.015229889 Gfi1-MA0038.1 0.024721508 FOXI1-MA0042.1 0.0193093 MZF1_1-4-MA0056.1 0.01513107 MZF1_5-13-MA0057.1 0.008614354 Nkx2-5-MA0063.1 0.0340167 Pax2-MA0067.1 0.01513107 SPIB-MA0081.1 0.01513107 Hand1::Tcfe2a-MA0092.1 0.0340167 REL-MA0101.1 0.008614354 RELA-MA0107.1 0.01513107 Zfp423-MA0116.1 0.037529914 Mafb-MA0117.1 0.018551837 Nkx3-2-MA0122.1 0.0193093 NKX3-1-MA0124.1 0.035916233 ZNF354C-MA0130.1 0.01513107 Pdx1-MA0132.1 0.036039382 BRCA1-MA0133.1 0.01513107 ELF5-MA0136.1 0.020754296 Pou5f1::Sox2-MA0142.1 0.02674396 Klf4-MA0039.2 0.01513107 ARID3A-MA0151.1 0.01513107 NFIC-MA0161.1 0.01513107 Zfx-MA0146.2 0.046964228 Atoh1-MA0461.1 0.01513107 CDX2-MA0465.1 0.02674396 E2F6-MA0471.1 0.042175595 Gata4-MA0482.1 0.042175595 Klf1-MA0493.1 0.049497154 Myod1-MA0499.1 0.020990595 SP2-MA0516.1 0.02674396 STAT2::STAT1-MA0517.1 0.01513107 Tcf12-MA0521.1 0.027878668 Tcf3-MA0522.1 0.02674396 EBF1-MA0154.2 0.02674396 NFKB1-MA0105.3 0.021028864 Sox2-MA0143.3 0.01513107 SP1-MA0079.3 0.008614354 ZEB1-MA0103.2 0.017159154 SREBF2-MA0596.1 0.01513107 THAP1-MA0597.1 0.01513107 EHF-MA0598.1 0.020396026 KLF5-MA0599.1 0.01513107 TFAP2A-MA0003.1 0.01513107 GATA2-MA0036.1 0.01513107 GATA3-MA0037.1 0.01513107 Gfi-MA0038.1 0.024721508 NF-kappaB-MA0061.1 0.01513107 USF1-MA0093.1 0.049497154 YY1-MA0095.1 0.01513107 ETS1-MA0098.1 0.01513107 Myb-MA0100.1 0.027878668 Pou5f1-MA0142.1 0.02674396 Zfx-MA0146.1 0.042373038 EBF1-MA0154.1 0.03400297 SPI1-MA0080.2 0.015746345 AP1-MA0099.2 0.01513107 SP1-MA0079.2 0.015224746 SOX10-MA0442.1 0.01513107