Results of Mann-Whitney U tests and point-biserial correlation analyses for the association of annotated transposase genes with normalized modification density. Mann-Whitney U tests were performed by comparing the normalized modification density between genes with the word “transposase” in their annotation and the rest of the genes in the genome. Point-biserial correlation coefficients were computed between normalized modification densities in contiguous 1-000 bp sequence segments and a Boolean indicator function denoting the presence of transposase annotated genes within each segment. Bonferroni adjusted p-values are provided. Both analyses were performed using the Python SciPy library (SciPy- RRID:SCR_008058) library.,,,,,,,,,,,,,,,,,,,,,,,,,,, ,,,,,,,,,,,,,,,,,,,,,,,,,,, Organism,Region,U_stat,U_p-val,Bonf_U_p_val,Rpbs_stat,R_p-val,Bonf_R_p_val,key_count,Non_key_count,Region,U_stat,U_p-val,Bonf_U_p_val,Rpbs_stat,R_p-val,Bonf_R_p_val,key_count,Non_key_count,Region,U_stat,U_p-val,Bonf_U_p_val,Rpbs_stat,R_p-val,Bonf_R_p_val,key_count,Non_key_count Ralstonia solanacearum strain UY031,Downstream,344385,9.74E-41,2.18E-38,0.254787312,1.89E-28,4.23E-26,322,1504,Intragenic,999872,5.40E-35,1.21E-32,0.409921597,3.79E-191,8.49E-189,322,4408,Upstream,479845,1.81E-28,4.05E-26,0.285158813,3.60E-48,8.06E-46,321,2189 Lactobacillus plantarum AG30,Downstream,104922,4.56E-34,1.02E-31,0.151423378,7.05E-10,1.58E-07,108,1533,Intragenic,206734.5,4.87E-17,1.09E-14,0.141419514,7.34E-16,1.64E-13,108,3114,Upstream,115193.5,5.15E-22,1.15E-19,0.166941632,6.62E-13,1.48E-10,107,1723 Methylocystis sp. LW5,Downstream,149676.5,1.05E-16,2.35E-14,0.16042489,7.31E-11,1.64E-08,142,1488,Intragenic,542098,4.06E-42,9.09E-40,0.202507308,3.89E-42,8.71E-40,155,4266,Upstream,229975.5,1.01E-16,2.26E-14,0.158437183,9.44E-15,2.11E-12,148,2215 Aminiphilus circumscriptus DSM 16581,Downstream,101738,6.95E-12,1.56E-09,0.020151968,0.472528444,1.06E+02,131,1142,Intragenic,295068,4.52E-30,1.01E-27,0.075113384,0.0000457,0.0102368,133,2807,Upstream,106071,0.00000787,0.00176288,0.023665118,0.369352976,82.73506662,132,1309 Pseudomonas aeruginosa NCAIM B.001380,Downstream,119228.5,3.88E-09,8.69E-07,0.210921859,1.31E-20,2.93E-18,98,1808,Intragenic,486923,5.03E-21,1.13E-18,0.218021415,2.20E-70,4.93E-68,99,6363,Upstream,179966,0.000191628,0.042924672,0.202598568,4.03E-30,9.03E-28,99,3006 Psychrilyobacter atlanticus DSM 19335,Downstream,44571.5,5.87E-08,1.31E-05,0.144180892,1.78E-07,3.99E-05,51,1249,Intragenic,108769,0.00000616,0.00137984,0.268346632,7.69E-54,1.72E-51,51,3145,Upstream,51047,0.000868664,0.194580736,0.145920166,2.72E-09,6.09E-07,51,1595 Thermoplasma volcanium GSS1,Downstream,18302.5,9.14E-07,2.05E-04,0.218454712,2.55E-06,5.71E-04,70,385,Intragenic,65198,0.004753106,1.064695744,0.11540631,0.00000354,0.00079296,72,1534,Upstream,33794,0.000000312,0.000069888,0.20860331,5.86E-09,1.31E-06,72,692 Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150,Downstream,54831,6.30E-06,1.41E-03,0.111958541,1.85E-05,4.14E-03,59,1397,Intragenic,158789,0.004920001,1.102080224,0.102623972,1.08E-11,2.42E-09,62,4302,Upstream,85128.5,0.0000394,0.0088256,0.109069802,0.000000267,0.000059808,61,2154 Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,Downstream,55197.5,6.86E-06,1.54E-03,0.09576342,0.000194934,4.37E-02,57,1452,Intragenic,165591,0.010697917,2.396333408,0.103019929,2.14E-12,4.79E-10,62,4566,Upstream,85350.5,0.000498059,0.111565216,0.095035355,0.00000484,0.00108416,61,2245 Acidovorax sp. JHL-3,Downstream,43611,0.003521732,7.89E-01,0.027783208,0.294264848,6.59E+01,52,1375,Intragenic,146332,1.04E-09,2.33E-07,0.059550617,0.000371515,0.08321936,57,3512,Upstream,52667.5,0.011047194,2.474571456,0.02264862,0.346324508,77.57668979,53,1678 Phaeobacter inhibens DSM 17395,Downstream,46097.5,0.000977766,2.19E-01,0.090752314,0.00064831,1.45E-01,55,1354,Intragenic,146125,0.0000124,0.0027776,0.222477459,3.09E-45,6.92E-43,57,3870,Upstream,61578.5,0.033106069,7.415759456,0.072270171,0.001409618,0.315754432,57,1892 Methanospirillum hungatei JF-1,Downstream,112397,2.49E-09,5.58E-07,0.238235139,4.18E-15,9.36E-13,211,846,Intragenic,371894.5,0.034157599,7.651302176,0.245507921,1.04E-48,2.33E-46,213,3250,Upstream,160050.5,0.000409478,0.091723072,0.207561219,1.98E-16,4.44E-14,211,1327 Haloterrigena turkmenica DSM 5511,Downstream,72037,0.003009117,6.74E-01,0.032206158,0.111583334,2.50E+01,49,2393,Intragenic,196962,4.50E-15,1.01E-12,0.161198795,3.94E-30,8.83E-28,49,4894,Upstream,91370.5,0.061145594,13.69661306,0.018345794,0.288160015,64.54784336,49,3305 Dyadobacter fermentans DSM 18053,Downstream,73444.5,0.003644141,8.16E-01,0.073827992,0.002211555,4.95E-01,77,1639,Intragenic,246863,0.050426647,11.29556893,0.183401704,5.56E-45,1.25E-42,78,5713,Upstream,118535.5,0.033792215,7.56945616,0.095435707,0.000000314,0.000070336,76,2786 Agrobacterium tumefaciens str. C58,Downstream,57671,0.001040754,2.33E-01,0.024112676,0.29133223,6.53E+01,59,1858,Intragenic,165056,0.087824762,19.67274669,0.024637398,0.070531582,15.79907437,60,5329,Upstream,85053,0.000454293,0.101761632,0.048089853,0.012018971,2.692249504,60,2667 Salmonella bongori NCTC 12419,Downstream,39342.5,0.0027773,6.22E-01,0.07635857,0.003506824,7.86E-01,45,1415,Intragenic,109768,0.062726245,14.05067888,0.077258707,0.000000729,0.000163296,48,4053,Upstream,59235,0.027448572,6.148480128,0.088816116,0.0000338,0.0075712,48,2125 Gillisia limnaea str. DSM 15749,Downstream,88974,0.011880884,2.66E+00,0.046723322,0.067416054,1.51E+01,111,1422,Intragenic,223703.5,0.001906767,0.427115808,0.12198043,3.63E-13,8.13E-11,113,3414,Upstream,104940,0.114249385,25.59186224,0.055159043,0.017145423,3.840574752,112,1755 Pyrococcus horikoshii OT3,Downstream,809,0.077607978,1.74E+01,0.071600545,0.305254272,6.84E+01,6,201,Intragenic,7855,0.035873926,8.035759424,0.06176425,0.007994936,1.790865664,6,1837,Upstream,2008,0.050957138,11.41439891,0.074167951,0.101739926,22.78974342,6,482 Holophaga foetida DSM 6591,Downstream,60387,0.019078687,4.27E+00,0.063148566,0.029113425,6.52E+00,98,1096,Intragenic,217937,0.001924564,0.431102336,0.146709771,1.14E-18,2.55E-16,108,3470,Upstream,82075.5,0.146315726,32.77472262,0.058901889,0.019283785,4.31956784,105,1473 Xylella fastidiosa Temecula1,Downstream,1588,0.132788999,2.97E+01,0.019208686,0.525642097,1.18E+02,2,1092,Intragenic,4141,0.014510768,3.250412032,0.051034441,0.016893394,3.784120256,2,2189,Upstream,1859,0.050984828,11.42060147,0.036172862,0.227257819,50.90575146,2,1114 Parabacteroides distasonis ATCC 8503,Downstream,20969.5,0.13637792,3.05E+01,0.153092339,1.32E-07,2.96E-05,33,1143,Intragenic,78970,0.043172843,9.670716832,0.205413203,2.09E-38,4.68E-36,35,3863,Upstream,31453,0.083970276,18.80934182,0.167463152,1.23E-11,2.76E-09,35,1582 Halomicrobium katesii DSM 19301,Downstream,141372,0.055531083,1.24E+01,0.076770922,0.003579792,8.02E-01,217,1221,Intragenic,448089,0.000000292,0.000065408,0.208694413,3.12E-37,6.99E-35,217,3436,Upstream,197770.5,0.231939358,51.95441619,0.087045179,0.000102726,0.023010624,217,1769 Bradyrhizobium elkanii USDA 76,Downstream,1235314.5,0.000523712,1.17E-01,0.089666847,1.30E-09,2.91E-07,572,3990,Intragenic,2938676.5,3.54E-12,7.93E-10,0.251838127,2.76E-130,6.18E-128,599,8405,Upstream,1513373,0.316621668,70.92325363,0.119039302,2.44E-19,5.47E-17,589,5078 Actinosynnema mirum DSM 43827,Downstream,94516.5,0.0610597,1.37E+01,0.008043531,0.672574241,1.51E+02,63,2700,Intragenic,251112.5,0.019721204,4.417549696,0.045850578,0.000125425,0.0280952,63,6929,Upstream,115655.5,0.413962638,92.72763091,0.001440071,0.930437984,208.4181084,63,3614 Orenia marismortui DSM 5156,Downstream,135079.5,1.18E-05,2.64E-03,0.01496727,0.546191694,1.22E+02,155,1473,Intragenic,238533.5,0.546150327,122.3376732,0.026471222,0.132489845,29.67772528,156,3075,Upstream,148082,0.002643811,0.592213664,0.056076087,0.016028256,3.590329344,155,1689 Rhodopseudomonas palustris CGA009,Downstream,36284,0.058060609,1.30E+01,0.029677819,0.173681216,3.89E+01,30,2073,Intragenic,120677,0.00000234,0.00052416,0.088398789,5.41E-10,1.21E-07,34,4879,Upstream,43768,0.500393297,112.0880985,-0.002689307,0.885790321,198.4170319,31,2824 Pedobacter heparinus HIM 762-3- DSM 2366,Downstream,1594,0.228632964,5.12E+01,0.002417019,0.942726905,2.11E+02,3,883,Intragenic,8149,0.193269037,43.29226429,0.017993953,0.242539439,54.32883434,3,4217,Upstream,2975.5,0.21321827,47.76089248,0.007792965,0.755139758,169.1513058,3,1601 Rhodopseudomonas palustris CGA009,Downstream,34614,0.143318433,3.21E+01,0.025954561,0.234152758,5.25E+01,30,2073,Intragenic,120677,0.00000234,0.00052416,0.088398789,5.41E-10,1.21E-07,34,4879,Upstream,43768,0.500393297,112.0880985,-0.002689307,0.885790321,198.4170319,31,2824 Thermogemmatispora sp. PM5,Downstream,2855.5,0.461292824,1.03E+02,-0.000432702,0.981911523,2.20E+02,2,2746,Intragenic,14523,0.099795909,22.35428362,0.014431931,0.340288572,76.22464013,5,4363,Upstream,9921,0.14210922,31.83246528,0.013116144,0.464447439,104.0362263,5,3108 Clostridium josui JCM 17888,Downstream,167768.5,0.065855486,1.48E+01,0.01329307,0.596344145,1.34E+02,233,1357,Intragenic,522799.5,0.0000012,0.0002688,0.142461742,2.55E-19,5.71E-17,239,3702,Upstream,201593.5,0.65090429,145.802561,-0.001534059,0.945818247,211.8632873,237,1728 Thermoplasma acidophilum DSM 1728,Downstream,5372,0.14509059,3.25E+01,0.027514247,0.566662613,1.27E+02,23,413,Intragenic,18401,0.45041064,100.8919834,0.008688638,0.733749665,164.359925,24,1511,Upstream,9145,0.136154055,30.49850832,0.027274742,0.454859778,101.8885903,22,731 Sediminibacter sp. Hel_I_10,Downstream,20205,0.025833171,5.79E+00,0.055611511,0.059280465,1.33E+01,30,1121,Intragenic,57094,0.242300759,54.27537002,0.084665456,0.0000004,0.0000896,30,3544,Upstream,22383.5,0.484526683,108.533977,0.027746167,0.264373102,59.21957485,28,1592 Ruminococcus sp. NK3A76,Downstream,72391.5,0.014227352,3.19E+00,0.053516693,0.052174077,1.17E+01,106,1211,Intragenic,203808,0.00000969,0.00217056,0.140250433,1.62E-15,3.63E-13,106,3092,Upstream,72609,0.834539268,186.936796,-0.01541142,0.543280423,121.6948148,106,1452 Treponema succinifaciens DSM 2489,Downstream,79573,0.116628205,2.61E+01,0.020808898,0.526433626,1.18E+02,210,719,Intragenic,297853,0.072891206,16.32763014,0.08461679,0.00000579,0.00129696,212,2651,Upstream,104862.5,0.735743008,164.8064338,-0.016855497,0.553671413,124.0223965,210,1027 Methanohalophilus mahii DSM 5219,Downstream,6128,0.25455561,5.70E+01,0.012800069,0.783324321,1.75E+02,26,438,Intragenic,28597,0.149668314,33.52570234,0.040476448,0.070824998,15.86479955,26,1967,Upstream,10937,0.531573044,119.0723619,-0.005752657,0.865069883,193.7756538,26,849 Polycyclovorans algicola TG408,Downstream,72376.5,0.098791664,2.21E+01,0.040266432,0.201927105,4.52E+01,161,845,Intragenic,261429,0.688584434,154.2429132,0.041401778,0.014799431,3.315072544,162,3303,Upstream,102655,0.172318833,38.59941859,0.050667901,0.060431877,13.53674045,162,1212 Corynebacterium aurimucosum ATCC 700975,Downstream,15455,0.389739194,8.73E+01,0.014191514,0.69915491,1.57E+02,43,701,Intragenic,69345,0.006743048,1.510442752,0.149940258,3.31E-14,7.41E-12,46,2487,Upstream,20387.5,0.58612522,131.2920493,0.03001908,0.345645206,77.42452614,44,945 Enterobacteriaceae bacterium strain FGI 57,Downstream,37304,0.001306735,2.93E-01,0.097861014,0.000233001,5.22E-02,43,1367,Intragenic,72139,0.991982645,222.2041125,-0.017557041,0.249327977,55.84946685,43,4264,Upstream,68612,4.52E-08,1.01E-05,0.152768797,5.45E-13,1.22E-10,43,2163 Clostridium clariflavum 4-2a,Downstream,522229,4.16E-12,9.32E-10,0.121708533,3.17E-09,7.10E-07,462,1891,Intragenic,736361,0.999948348,223.98843,0.090211747,1.27E-08,2.84E-06,474,3490,Upstream,550616,0.000000631,0.000141344,0.167552748,2.06E-17,4.61E-15,466,2068 Niabella soli DSM 19437,Downstream,29272,0.003630904,8.13E-01,0.012092415,0.618318755,1.39E+02,29,1671,Intragenic,53506.5,0.755652686,169.2662017,0.030092817,0.060990241,13.66181398,30,3847,Upstream,32447.5,0.247339125,55.403964,0.010337861,0.639034986,143.1438369,30,2031 Clostridium sp. ASBs410,Downstream,49490.5,0.00116895,2.62E-01,0.00681546,0.762120465,1.71E+02,42,1933,Intragenic,90797,0.983455814,220.2941023,-0.031260611,0.023561989,5.277885536,43,5203,Upstream,60247.5,0.024800771,5.555372704,0.017190769,0.395611412,88.61695629,43,2401 Ruminococcaceae bacterium AE2021,Downstream,26287.5,0.207604323,4.65E+01,0.005910753,0.870600286,1.95E+02,72,690,Intragenic,125949,0.000133327,0.029865248,0.157288145,2.40E-17,5.38E-15,72,2796,Upstream,35599.5,0.829971107,185.913528,-0.033537232,0.259557482,58.14087597,72,1060 Bacteroides salanitronis DSM 18170,Downstream,128706,0.033429039,7.49E+00,0.016781915,0.495996544,1.11E+02,159,1489,Intragenic,319509.5,0.01101939,2.46834336,0.082295169,0.000000453,0.000101472,161,3587,Upstream,114325,0.99793862,223.5382509,-0.062868064,0.006409679,1.435768096,154,1725 Nitriliruptor alkaliphilus DSM 45188,Downstream,76026.5,0.000257603,5.77E-02,0.032187441,0.205911218,4.61E+01,88,1458,Intragenic,173783.5,0.999971153,223.9935383,-0.024994149,0.071024637,15.90951869,90,5128,Upstream,122560,0.05171549,11.58426976,0.04012867,0.041577804,9.313428096,90,2489 Planctomyces limnophilus DSM 3776,Downstream,53987.5,0.010662598,2.39E+00,0.019499869,0.332583279,7.45E+01,37,2434,Intragenic,73114,0.875446682,196.1000568,0.015530917,0.305564837,68.44652349,38,4316,Upstream,56714,0.169712472,38.01559373,0.032113411,0.086514581,19.37926614,37,2813 Mycoplasma bovis PG45,Downstream,20680,0.071939583,1.61E+01,0.02789495,0.576600996,1.29E+02,151,252,Intragenic,34229,1,224,-0.316938,5.84E-23,1.31E-20,151,771,Upstream,28199,0.024385118,5.462266432,0.056490067,0.213345968,47.78949683,151,336 Hippea sp.KM1,Downstream,5055,0.132406661,2.97E+01,0.077774324,0.272454523,6.10E+01,71,130,Intragenic,82393,0.00000589,0.00131936,0.204215677,6.52E-18,1.46E-15,76,1672,Upstream,8480.5,0.999822023,223.9601332,-0.174802542,0.000589795,0.13211408,75,308 Gillisia sp. JM1,Downstream,115546.5,0.026921635,6.03E+00,0.040551647,0.13172871,2.95E+01,176,1207,Intragenic,252926.5,0.731481241,163.851798,0.029583167,0.098725316,22.11447078,177,2939,Upstream,130399.5,0.399558015,89.50099536,0.035795016,0.146367678,32.78635987,175,1473 Geovibrio sp. L21 Ace-BES,Downstream,21607.5,0.046086444,1.03E+01,0.082259247,0.034203122,7.66E+00,64,599,Intragenic,62782.5,0.999833953,223.9628055,0.008732404,0.648766092,145.3236046,64,2659,Upstream,31522.5,0.145211249,32.52731978,0.080755177,0.011567918,2.591213632,64,913 Maribacter sp. Hel_I _7,Downstream,9071.5,0.195219632,4.37E+01,0.004225966,0.889012778,1.99E+02,15,1078,Intragenic,31310.5,0.43694997,97.87679328,0.012094521,0.439192357,98.37908797,15,4078,Upstream,12952,0.562144422,125.9203505,-0.009791567,0.679478687,152.2032259,15,1768 Thiobacillus denitrificans ATCC 25259,Downstream,1800.5,0.302178916,6.77E+01,0.007367645,0.85242401,1.91E+02,5,635,Intragenic,10043,0.434184985,97.25743664,0.009519623,0.616122653,138.0114743,7,2769,Upstream,2804.5,0.493357795,110.5121461,-0.002412422,0.941211815,210.8314466,6,931 Lachnoclostridium phytofermentans KNHs212,Downstream,125778.5,0.000434005,9.72E-02,0.004712201,0.820693785,1.84E+02,96,2220,Intragenic,181228.5,0.752031745,168.4551109,-0.001656763,0.916667638,205.3335509,97,3894,Upstream,114127.5,0.516750898,115.7522012,-0.008828011,0.661904822,148.2666801,97,2359 Methylophilus sp. 5,Downstream,11425,0.027933095,6.26E+00,-0.00485365,0.892481991,2.00E+02,26,752,Intragenic,31574,0.92408721,206.995535,0.009201237,0.625994764,140.2228271,27,2781,Upstream,16066,0.325573109,72.92837642,-0.006156215,0.830812929,186.1020961,26,1181 Sphaerobacter thermophilus DSM 20745,Downstream,49504.5,0.324011828,7.26E+01,0.011499862,0.640145169,1.43E+02,60,1595,Intragenic,110766,0.151727692,33.98700301,0.064876789,0.000126233,0.028276192,60,3427,Upstream,55510,0.805486961,180.4290793,-0.003796181,0.862857919,193.2801739,59,2014 Thermacetogenium phaeum DSM 12270,Downstream,118874,0.011698512,2.62E+00,0.034105094,0.228599215,5.12E+01,208,1040,Intragenic,200771,1,224,-0.103702035,1.87E-08,4.19E-06,215,2712,Upstream,126697.5,0.324713262,72.73577069,0.047885741,0.073475556,16.45852454,209,1189 Ruminococcus albus AD2013,Downstream,122439.5,0.336755617,7.54E+01,0.004883993,0.843896768,1.89E+02,164,1464,Intragenic,354272.5,0.0000107,0.0023968,0.091669967,2.31E-08,5.17E-06,168,3533,Upstream,121731,0.999861716,223.9690244,-0.03453788,0.128925549,28.87932298,166,1768 Staphylothermus marinus F1,Downstream,2065,0.187956878,4.21E+01,0.024468049,0.625184464,1.40E+02,9,392,Intragenic,6474.5,0.692111123,155.0328916,-0.019642729,0.432065413,96.78265251,9,1593,Upstream,2945.5,0.461667895,103.4136085,-0.010943192,0.767863316,172.0013828,8,722 Clostridium algidicarnis strain B3,Downstream,45250,0.037572043,8.42E+00,0.00779686,0.77782898,1.74E+02,65,1247,Intragenic,75452,0.989418029,221.6296385,-0.009342437,0.623520752,139.6686484,67,2696,Upstream,50052.5,0.385819743,86.42362243,0.023673977,0.354607935,79.43217744,67,1464 Chloroflexus aggregans DSM 9485,Downstream,32210,0.26143851,5.86E+01,-0.005533142,0.840764015,1.88E+02,48,1273,Intragenic,77703,0.989039478,221.5448431,-0.018561371,0.252843542,56.63695341,51,3746,Upstream,45237.5,0.178276553,39.93394787,0.016895501,0.465516703,104.2757415,46,1822 Sporocytophaga myxococcoides DSM 11118,Downstream,3363,0.421017918,9.43E+01,-0.00720212,0.865568259,1.94E+02,12,543,Intragenic,12136,0.159349273,35.69423715,0.055950263,0.02423568,5.42879232,13,1609,Upstream,3857,0.855967487,191.7367171,-0.035931749,0.311912844,69.86847706,12,782 Bacteroides sp. 14(A),Downstream,41851.5,0.448577825,1.00E+02,-0.012548124,0.590033511,1.32E+02,46,1800,Intragenic,196722.5,0.001302772,0.291820928,0.064113264,0.00000236,0.00052864,60,5350,Upstream,44936,0.992045477,222.2181868,-0.045989306,0.022766697,5.099740128,47,2405 Butyrivibrio sp. AE3004,Downstream,101715.5,0.027981371,6.27E+00,0.021162219,0.39290977,8.80E+01,123,1509,Intragenic,234441,0.545065072,122.0945761,0.092412919,5.73E-09,1.28E-06,123,3835,Upstream,103403,0.910591365,203.9724658,0.001920166,0.932747048,208.9353388,123,1811 Sulfolobus acidocaldarius DSM 639,Downstream,3398.5,0.533441154,1.19E+02,-0.008531204,0.829714194,1.86E+02,11,627,Intragenic,13883,0.419764407,94.02722717,0.019257001,0.36123369,80.91634656,12,2238,Upstream,4812,0.543775406,121.8056909,0.004105265,0.901954521,202.0378127,11,892 Nocardia sp. BMG111209,Downstream,112903,0.101618499,2.28E+01,-0.011131347,0.580601333,1.30E+02,88,2378,Intragenic,371405.5,0.774818528,173.5593503,-0.004239958,0.704047384,157.706614,98,7931,Upstream,191112,0.646965393,144.920248,-0.013504897,0.383339482,85.86804397,96,4073 Arthrobacter sp. 31Y,Downstream,10849.5,0.580884187,1.30E+02,-0.012506608,0.648486246,1.45E+02,17,1314,Intragenic,52372.5,0.259388596,58.1030455,0.037641139,0.01039803,2.32915872,21,4612,Upstream,19463,0.688718031,154.2728389,-0.004665348,0.830846491,186.109614,20,2079 Clostridium indolis DSM 755,Downstream,90682.5,0.001242384,2.78E-01,0.017522513,0.419802517,9.40E+01,75,2047,Intragenic,161062.5,0.999964922,223.9921425,-0.03875648,0.00327308,0.73316992,77,5679,Upstream,93626,0.531866325,119.1380568,0.000696551,0.971762743,217.6748544,75,2510 Methylophilaceae bacterium 11,Downstream,1011,0.278590025,6.24E+01,0.048750027,0.24398081,5.47E+01,3,570,Intragenic,2936.5,0.762329584,170.7618268,0.081557901,0.0000346,0.0077504,3,2569,Upstream,1379.5,0.53164148,119.0876915,0.046188351,0.155534412,34.83970829,3,944 Sebaldella termitidis ATCC 33386,Downstream,31123,0.756355173,1.69E+02,-0.006836438,0.78062935,1.75E+02,41,1621,Intragenic,91186,0.178217214,39.92065594,0.052839461,0.000664906,0.148938944,41,4105,Upstream,37347,0.643519085,144.148275,0.014355019,0.528949177,118.4846156,41,1885 Exiguobacterium aurantiacum DSM 6208,Downstream,89729,0.429762772,9.63E+01,0.068543418,0.028675731,6.42E+00,224,795,Intragenic,344656,0.164906594,36.93907706,0.131799968,1.00E-13,2.24E-11,226,2936,Upstream,123327,0.999988145,223.9973445,0.007326125,0.773192871,173.1952031,226,1324 Persephonella sp. IF05-L8,Downstream,1735.5,0.346410226,7.76E+01,0.088250695,0.20276003,4.54E+01,17,193,Intragenic,16500,0.557083299,124.786659,0.06762522,0.003284121,0.735643104,18,1870,Upstream,3196.5,0.691622844,154.9235171,0.017637316,0.717897288,160.8089925,17,405 Tolumonas sp. BRL6-1,Downstream,20802.5,0.151540769,3.39E+01,0.018685813,0.58073729,1.30E+02,46,830,Intragenic,57527.5,0.996120049,223.130891,-0.047211187,0.006785152,1.519874048,46,3241,Upstream,34587,0.543216552,121.6805076,0.001664837,0.947547066,212.2505428,46,1518 Akkermansia muciniphila ATCC BAA-835,Downstream,2571.5,0.772052623,1.73E+02,-0.03276448,0.330258839,7.40E+01,7,878,Intragenic,9052,0.247912605,55.53242352,0.0000414,0.998430245,223.6483749,7,2251,Upstream,2740.5,0.674822427,151.1602236,-0.022716242,0.466674476,104.5350826,6,1023 Streptobacillus moniliformis DSM 12112,Downstream,7885.5,0.184538206,4.13E+01,-0.027316097,0.594076044,1.33E+02,43,340,Intragenic,27097,0.937893982,210.088252,-0.021628097,0.401935584,90.03357082,43,1461,Upstream,9174.5,0.572946246,128.3399591,-0.012751683,0.781180059,174.9843332,43,434 Fervidobacterium nodosum Rt17-B1,Downstream,20237.5,0.167920135,3.76E+01,-0.032563268,0.502665758,1.13E+02,129,297,Intragenic,91003.5,0.999886432,223.9745608,-0.006993416,0.761867505,170.6583211,129,1751,Upstream,33744.5,0.551618101,123.5624546,0.016754066,0.66841442,149.7248301,129,527 Lachnoclostridium phytofermentans KNHs2132,Downstream,113786,0.126379694,2.83E+01,-0.003379298,0.870797015,1.95E+02,96,2223,Intragenic,171024.5,0.946378162,211.9887083,-0.018007219,0.255102485,57.14295664,97,3899,Upstream,111518.5,0.669129162,149.8849323,-0.012446279,0.537383539,120.3739127,97,2361 Dinoroseobacter shibae DFL 12,Downstream,119437.5,0.003781393,8.47E-01,0.025879808,0.342926514,7.68E+01,185,1160,Intragenic,379048.5,0.846091863,189.5245773,0.0755879,0.000000699,0.000156576,193,4106,Upstream,149679,0.90863403,203.5340227,-0.003586142,0.875184965,196.0414322,183,1738 Methylophilus sp. 42,Downstream,1277,0.645789346,1.45E+02,-0.000258149,0.99449436,2.23E+02,4,713,Intragenic,4214.5,0.789424206,176.8310221,0.025852297,0.175395451,39.28858102,4,2745,Upstream,2525,0.365853834,81.95125882,0.022014914,0.455175324,101.9592726,4,1149 Streptomyces sp. WMMB 714,Downstream,125,0.51900603,1.16E+02,-0.013371398,0.880450306,1.97E+02,2,127,Intragenic,177,0.616524763,138.1015469,-0.016592169,0.814241037,182.3899923,2,201,Upstream,128,0.666566187,149.3108259,-0.032163463,0.689237496,154.3891991,2,155 Thermosipho melanesiensis BI429,Downstream,1694.5,0.456067777,1.02E+02,0.014955579,0.807106034,1.81E+02,13,256,Intragenic,13566,0.627116987,140.4742051,0.028898085,0.206097438,46.16582611,15,1901,Upstream,2443,0.748608164,167.6882287,-0.01434343,0.773790088,173.3289797,14,390 Desulforegula conservatrix Mb1Pa,Downstream,131.5,0.385800313,8.64E+01,0.006681409,0.966503359,2.16E+02,7,35,Intragenic,348,0.717180388,160.6484069,-0.064754844,0.507549731,113.6911397,8,99,Upstream,123,0.730432664,163.6169167,-0.100965027,0.494723475,110.8180584,7,41 Thermoanaerobacter sp. X514,Downstream,35894.5,0.0948156,2.12E+01,0.006727994,0.853475918,1.91E+02,102,654,Intragenic,98971.5,0.99854343,223.6737283,-0.01466008,0.470362357,105.361168,103,2324,Upstream,42431.5,0.75955636,170.1406246,0.000907936,0.97755153,218.9715427,103,860 Flavobacterium psychrophilum JIP02/86,Downstream,54057,0.786393192,1.76E+02,-0.033550876,0.285097959,6.39E+01,127,890,Intragenic,155239,0.361583495,80.99470288,0.017381913,0.382439728,85.66649907,127,2400,Upstream,66066,0.718102373,160.8549316,-0.015986332,0.579940269,129.9066203,127,1074 Solitalea canadensis DSM 3403,Downstream,84168,0.062578012,1.40E+01,0.011776073,0.610238801,1.37E+02,87,1789,Intragenic,155375.5,0.999611767,223.9130358,0.006163364,0.683121311,153.0191737,91,4298,Upstream,95500,0.846704132,189.6617256,0.004117323,0.839342485,188.0127166,87,2340 Sediminibacterium sp. OR53,Downstream,27231.5,0.055315538,1.24E+01,-0.038254652,0.311821041,6.98E+01,82,619,Intragenic,92611.5,0.999999398,223.9998652,-0.008128972,0.643030379,144.0388049,84,3169,Upstream,43534.5,0.890565101,199.4865826,-0.05254124,0.069542651,15.57755382,84,1110 Treponema caldaria DSM 7334,Downstream,29535,0.231816463,5.19E+01,0.078064766,0.036629314,8.20E+00,90,627,Intragenic,111242.5,0.988943379,221.5233169,0.087093972,0.0000026,0.0005824,92,2812,Upstream,42634.5,0.726209807,162.6709968,0.073741987,0.016085381,3.603125344,91,974 Mastigocladopsis repens PCC 10914,Downstream,455425,0.000122838,2.75E-02,0.038406071,0.026742715,5.99E+00,266,3061,Intragenic,546778.5,1,224,-0.013897471,0.295767759,66.25197802,298,5364,Upstream,484733.5,0.951740988,213.1899813,0.051632944,0.001037452,0.232389248,274,3759 Prevotella sp. 10(H),Downstream,24747,0.06174121,1.38E+01,0.027246,0.368830895,8.26E+01,42,1048,Intragenic,59937.5,0.987963829,221.3038977,0.058939424,0.000461553,0.103387872,43,3484,Upstream,31161.5,0.905881353,202.9174231,0.018801493,0.435562949,97.56610058,42,1680 Peptostreptococcaceae bacterium VA2,Downstream,44780,0.419249389,9.39E+01,-0.007531841,0.76664047,1.72E+02,59,1496,Intragenic,95066.5,0.577396049,129.336715,0.036880198,0.033325537,7.464920288,59,3271,Upstream,44701.5,0.977302894,218.9158483,-0.011241739,0.626356215,140.3037922,58,1820 Frankia sp. DC12,Downstream,417317,0.000197963,4.43E-02,0.001708751,0.923869743,2.07E+02,262,2868,Intragenic,602619.5,0.999999997,223.9999993,-0.010425135,0.432417004,96.8614089,281,5392,Upstream,468854.5,0.979247868,219.3515224,0.002486006,0.876333313,196.2986621,277,3644 Acidobacteria bacterium KBS 146,Downstream,5425,0.761444305,1.71E+02,-0.023801026,0.342141892,7.66E+01,8,1587,Intragenic,17846,0.318503149,71.34470538,0.002303086,0.883123847,197.8197417,8,4069,Upstream,6647,0.913593804,204.6450121,-0.030353633,0.144551752,32.37959245,8,2304 Xenorhabdus nematophila ATCC 19061,Downstream,840344,4.76E-09,1.07E-06,-0.030244308,0.130583491,2.93E+01,983,1517,Intragenic,1297715.5,1,224,-0.099744252,1.05E-11,2.35E-09,998,3629,Upstream,873879,0.997734542,223.4925374,-0.030821443,0.098182995,21.99299088,984,1896 Neisseria meningitidis FAM18,Downstream,61690,0.999868726,2.24E+02,-0.063131933,0.040251214,9.02E+00,169,887,Intragenic,220515,0.00000135,0.0003024,0.083974397,0.0000567,0.0127008,171,2122,Upstream,60055.5,1,224,-0.1216734,0.0000265,0.005936,171,1015 Kangiella aquimarina DSM 16071,Downstream,199.5,0.739792584,1.66E+02,-0.023731399,0.550877207,1.23E+02,1,633,Intragenic,1999,0.674931666,151.1846932,-0.007174994,0.722342527,161.804726,2,2453,Upstream,1020.5,0.588765093,131.8833808,-0.008860274,0.76657486,171.7127686,2,1123 Streptosporangium roseum DSM 43021,Downstream,730854.5,0.006425873,1.44E+00,-0.023913029,0.111522359,2.50E+01,335,4095,Intragenic,1131323.5,1,224,-0.00832497,0.424860258,95.16869779,342,8849,Upstream,750260,0.997203272,223.3735329,-0.015353521,0.267806538,59.98866451,336,4875 Capnocytophaga ochracea DSM 7271,Downstream,1496.5,0.740473789,1.66E+02,-0.030859685,0.407366368,9.13E+01,5,718,Intragenic,5798.5,0.382638577,85.71104125,0.00272763,0.89922779,201.427025,5,2153,Upstream,1683.5,0.881846698,197.5336604,-0.039276941,0.220216939,49.32859434,5,971 Sedimentitalea nanhaiensis DSM 24252,Downstream,159708.5,0.635299885,1.42E+02,0.001106023,0.96539676,2.16E+02,251,1290,Intragenic,580689,0.3702397,82.9336928,0.098489692,1.28E-11,2.87E-09,258,4447,Upstream,192641.5,0.999824864,223.9607695,-0.006883393,0.754058357,168.909072,245,1829 Cellulophaga algicola DSM 14237,Downstream,142224.5,0.008212117,1.84E+00,-0.015506196,0.539634857,1.21E+02,189,1378,Intragenic,330058,0.999874975,223.9719944,0.017769798,0.243472402,54.53781805,190,4120,Upstream,161342,0.997740226,223.4938106,-0.059547973,0.006083269,1.362652256,190,1931 Caldicoprobacter oshimai DSM 21659,Downstream,70100,0.948117728,2.12E+02,-0.064785817,0.025240849,5.65E+00,146,1047,Intragenic,192254,0.072741989,16.29420554,0.102562619,0.000000217,0.000048608,150,2394,Upstream,68044,0.999979178,223.9953359,-0.101234125,0.000189503,0.042448672,142,1213 Eubacterium sp. AB3007,Downstream,14179.5,0.987858588,2.21E+02,-0.046665787,0.240661491,5.39E+01,60,574,Intragenic,73002,0.048619048,10.89066675,0.143650624,3.84E-11,8.60E-09,64,2034,Upstream,16923,0.999990449,223.9978606,-0.113182838,0.000995094,0.222901056,64,779 Nocardia sp. BMG51109,Downstream,150059.5,0.32218673,7.22E+01,0.004249639,0.80427851,1.80E+02,88,3315,Intragenic,322175,0.803341199,179.9484286,0.010851487,0.345481633,77.38788579,91,7469,Upstream,180480,0.919228437,205.9071699,-0.015101968,0.31498322,70.55624128,91,4338 Methylohalobius crimeensis 10Ki,Downstream,55957.5,0.339505917,7.60E+01,-0.005761978,0.859149194,1.92E+02,134,817,Intragenic,225768,0.796615035,178.4417678,-0.005573139,0.744824626,166.8407162,144,3269,Upstream,76988.5,0.916420167,205.2781174,-0.042323004,0.12038765,26.9668336,137,1211 Clostridium methoxybenzovorans SR3,Downstream,448446,0.066975834,1.50E+01,-0.019172921,0.320295027,7.17E+01,373,2316,Intragenic,952626.5,1,224,-0.027412004,0.024901041,5.577833184,388,6307,Upstream,473471.5,0.999773794,223.9493299,-0.030889808,0.082340848,18.44434995,378,2786 Polaromonas sp. EUR3 1.2.1,Downstream,162037,0.775367503,1.74E+02,-0.025463756,0.28828483,6.46E+01,220,1521,Intragenic,483781.5,0.351547464,78.74663194,0.011993445,0.437232239,97.94002154,241,3957,Upstream,193582.5,0.941834403,210.9709063,-0.030669737,0.161435185,36.16148144,222,1864 Palaeococcus ferrophilus DSM 13482,Downstream,3952.5,0.621922423,1.39E+02,-0.036529587,0.459077908,1.03E+02,21,392,Intragenic,21298.5,0.820615922,183.8179665,-0.015276762,0.46243836,103.5861926,21,2295,Upstream,7815,0.629635704,141.0383977,-0.020221956,0.568399143,127.321408,21,777 Lachnospiraceae bacterium AC2029,Downstream,77617.5,0.8946643,2.00E+02,-0.03381361,0.207545708,4.65E+01,132,1259,Intragenic,207676.5,0.181434289,40.64128074,0.086392574,0.00000136,0.00030464,133,2984,Upstream,63447,0.999999981,223.9999957,-0.114354288,0.0000079,0.0017696,129,1390 Desulfotignum balticum DSM 7044,Downstream,68910.5,0.329998673,7.39E+01,-0.010990278,0.697761815,1.56E+02,119,1132,Intragenic,239426.5,0.999983979,223.9964113,-0.04943913,0.000632806,0.141748544,131,4643,Upstream,102661,0.753314868,168.7425304,-0.002884657,0.900450209,201.7008468,121,1762 Alteromonas sp. ALT199,Downstream,22031,0.274565391,6.15E+01,0.003763914,0.87515137,1.96E+02,24,1721,Intragenic,36740,0.961510219,215.3782891,0.010952671,0.494381564,110.7414703,24,3871,Upstream,23487.5,0.851682803,190.7769479,-0.004404866,0.83436659,186.8981162,24,2232 Acidobacterium sp. PMMR2,Downstream,19610,0.869017176,1.95E+02,-0.044230056,0.181068924,4.06E+01,50,866,Intragenic,83252,0.242599129,54.3422049,0.025269188,0.156881241,35.14139798,51,3089,Upstream,24699.5,0.999694069,223.9314715,-0.085268519,0.001091831,0.244570144,49,1415 Clostridium sp. KNHs205,Downstream,128044,0.177490997,3.98E+01,-0.030209674,0.104800449,2.35E+01,87,2797,Intragenic,160559,0.999999985,223.9999966,-0.057224982,0.0000315,0.007056,93,5191,Upstream,121086,0.996097001,223.1257282,-0.042920581,0.01417961,3.17623264,91,3174 Robinsoniella sp. KNHs210,Downstream,151920,0.21609766,4.84E+01,-0.037221058,0.061578948,1.38E+01,122,2401,Intragenic,328409,0.988386548,221.3985868,0.033830151,0.009125538,2.044120512,128,5811,Upstream,139417,0.999998265,223.9996114,-0.074529394,0.000039,0.008736,126,2914 Butyrivibrio sp. AE3003,Downstream,44286,0.541831607,1.21E+02,-0.000639157,0.983014495,2.20E+02,87,1025,Intragenic,136984,0.727760618,163.0183784,0.03773371,0.03231708,7.23902592,91,3127,Upstream,47953,0.990207889,221.8065671,-0.036374362,0.178762557,40.04281277,88,1280 Lactobacillus brevis AG48,Downstream,77834,0.999998119,2.24E+02,-0.07788294,0.007720234,1.73E+00,203,966,Intragenic,255644.5,0.262812946,58.8700999,0.128077756,3.48E-11,7.80E-09,203,2453,Upstream,87922.5,1,224,-0.114914039,0.00000791,0.00177184,203,1301 Enterobacter aerogenes FGI35,Downstream,22828,0.474507741,1.06E+02,-0.01482268,0.578393525,1.30E+02,33,1375,Intragenic,52439,0.999141237,223.8076371,-0.048838241,0.000830247,0.185975328,33,4648,Upstream,34932,0.800498902,179.311754,-0.011200888,0.581731484,130.3078524,32,2389 Methanocaldococcus jannaschii DSM 2661,Downstream,285384,0.741210648,1.66E+02,-0.012023459,0.563628791,1.26E+02,282,2027,Intragenic,1349950,0.737765513,165.2594749,-0.006011042,0.555668961,124.4698473,290,9323,Upstream,310505,0.827298506,185.3148653,-0.016966863,0.396638301,88.84697942,281,2217 Polaribacter sp. Hel_I_88,Downstream,72054.5,0.690436936,1.55E+02,-0.033424801,0.212493044,4.76E+01,116,1277,Intragenic,191027.5,0.633501328,141.9042975,0.038846123,0.022079572,4.945824128,116,3356,Upstream,69507,0.999944856,223.9876477,-0.083407891,0.000645093,0.144500832,114,1556 Selenomonas ruminantium AB3002,Downstream,73955.5,0.997543168,2.23E+02,-0.073476195,0.006571323,1.47E+00,141,1226,Intragenic,249807.5,0.326588883,73.15590979,0.069804641,0.0000383,0.0085792,147,3326,Upstream,72784.5,1,224,-0.134682051,3.83E-08,8.58E-06,142,1512 Staphylococcus epidermidis AG42,Downstream,69702.5,0.397887284,8.91E+01,-0.045165204,0.106970393,2.40E+01,119,1156,Intragenic,125271,0.935191369,209.4828667,-0.000262997,0.989697752,221.6922964,119,2294,Upstream,61281.5,0.999870739,223.9710455,-0.092593218,0.000503673,0.112822752,119,1289 Spirochaeta smaragdinae DSM 11293,Downstream,20357.5,0.391656066,8.77E+01,-0.00770305,0.827258808,1.85E+02,53,752,Intragenic,98159,0.966836461,216.5713673,0.04785363,0.001681344,0.376621056,54,4253,Upstream,27560,0.988674128,221.4630047,-0.025914645,0.345533725,77.3995544,53,1274 Klebsiella sp. BRL6-2,Downstream,37898,0.482701569,1.08E+02,-0.01143835,0.635167762,1.42E+02,45,1678,Intragenic,85793.5,0.999889352,223.9752148,-0.051849998,0.000177654,0.039794496,48,5175,Upstream,57074,0.876864492,196.4176462,-0.020331692,0.292454404,65.5097865,48,2635 Methylobacterium sp. EUR3 AL-11,Downstream,236746,0.701426712,1.57E+02,-0.004137052,0.827833024,1.85E+02,188,2578,Intragenic,618032.5,0.679572154,152.2241625,0.024396593,0.045419983,10.17407619,193,6533,Upstream,306641,0.996665349,223.2530382,-0.024423088,0.126152221,28.2580975,186,3737 Desulfovibrio sp. L21-Syr-AB,Downstream,38948,0.984618555,2.21E+02,-0.033599322,0.325031782,7.28E+01,120,740,Intragenic,211762.5,0.410752814,92.00863034,0.090363961,0.000000286,0.000064064,136,3079,Upstream,64153,0.99174599,222.1511018,-0.010117876,0.720384716,161.3661764,131,1123 Ruminococcus sp. HUN007,Downstream,122103,0.419167264,9.39E+01,-0.026881841,0.252611908,5.66E+01,145,1668,Intragenic,238740.5,0.968254096,216.8889175,0.003744392,0.820633846,183.8219815,149,3520,Upstream,98407,0.999995361,223.9989609,-0.085608305,0.000130009,0.029122016,137,1856 Staphylococcus aureus subsp. aureus USA300_TCH1516,Downstream,48485,0.406393139,9.10E+01,-0.019741829,0.471418139,1.06E+02,76,1257,Intragenic,95293,0.983226105,220.2426475,0.009052921,0.626990442,140.445859,79,2805,Upstream,41477.5,0.999955675,223.9900712,-0.074568527,0.003868653,0.866578272,79,1420 Persephonella lauensis KM09-Lau-8,Downstream,1184.5,0.829290683,1.86E+02,-0.043036017,0.481308602,1.08E+02,11,259,Intragenic,14749,0.739177875,165.575844,0.006576136,0.75840656,169.8830694,15,2175,Upstream,2563.5,0.844530945,189.1749317,-0.030268786,0.50602928,113.3505587,13,472 Pontibacter actiniarum DSM 19842,Downstream,66173.5,0.867365654,1.94E+02,-0.013213053,0.548734743,1.23E+02,72,1990,Intragenic,150126.5,0.594836485,133.2433726,0.06704323,0.0000105,0.002352,72,4240,Upstream,76961.5,0.986209997,220.9110393,-0.012243699,0.533159446,119.4277159,72,2521 Hydrogenovibrio marinus DSM 11271,Downstream,23407,0.751791177,1.68E+02,-0.029140106,0.436572969,9.78E+01,74,641,Intragenic,89066,0.871951191,195.3170668,-0.0231179,0.246764514,55.27525114,75,2437,Upstream,37827,0.826523568,185.1412792,-0.024741626,0.411491378,92.17406867,75,1029 Actinobacillus succinogenes 130Z,Downstream,1903.5,0.752173971,1.68E+02,0.007417504,0.838023711,1.88E+02,6,756,Intragenic,4997.5,0.811654817,181.810679,0.060347381,0.005544259,1.241914016,6,2105,Upstream,2110.5,0.888999652,199.135922,-0.002571241,0.935438425,209.5382072,6,989 Methylophilus sp. 1,Downstream,1119,0.772988936,1.73E+02,-0.034569102,0.354986886,7.95E+01,4,714,Intragenic,4016,0.823695237,184.5077331,-0.017297096,0.364640693,81.67951523,4,2745,Upstream,1572.5,0.863046838,193.3224917,-0.029742876,0.312729641,70.05143958,4,1150 Clostridium mangenotii LM2,Downstream,13417,0.612630373,1.37E+02,-0.027781169,0.28467705,6.38E+01,19,1466,Intragenic,22496.5,0.923551097,206.8754457,-0.027761377,0.14329635,32.0983824,20,2761,Upstream,11724.5,0.949538229,212.6965633,-0.041498406,0.097253964,21.78488794,19,1579 Prevotella sp. HUN102,Downstream,104390,0.572977903,1.28E+02,-0.039897215,0.118775537,2.66E+01,153,1377,Intragenic,195945.5,0.961081495,215.2822549,-0.012510248,0.498242621,111.6063471,154,2779,Upstream,77066,1,224,-0.139243848,2.38E-08,5.33E-06,154,1440 Meiothermus chliarophilus DSM 9957,Downstream,99603,0.534699923,1.20E+02,0.002884532,0.897984461,2.01E+02,107,1871,Intragenic,109677,1,224,-0.116991111,6.03E-15,1.35E-12,112,4309,Upstream,83283,0.999995297,223.9989465,-0.064325293,0.002460678,0.551191872,106,2108 Thiomicrospira pelophila DSM 1534,Downstream,855.5,0.930950988,2.09E+02,-0.06903412,0.145515046,3.26E+01,6,440,Intragenic,5326,0.667961921,149.6234703,-0.021588824,0.336492918,75.37441363,6,1978,Upstream,1248.5,0.965332629,216.2345089,-0.067450038,0.067422603,15.10266307,6,730 Arthrobacter chlorophenolicus A6,Downstream,9997,0.725769852,1.63E+02,-0.03361714,0.212513886,4.76E+01,16,1361,Intragenic,26769.5,0.965530459,216.2788228,0.002679792,0.856499706,191.8559341,16,4540,Upstream,13856,0.905604565,202.8554226,-0.025227489,0.242739442,54.37363501,16,2130 Enterococcus gallinarum strain SKF1,Downstream,111572,0.60544792,1.36E+02,-0.064574037,0.011826252,2.65E+00,167,1352,Intragenic,218270,0.999998259,223.99961,-0.022300122,0.194721888,43.61770291,172,3211,Upstream,100778.5,0.999999812,223.9999579,-0.106453691,0.00000829,0.00185696,167,1579 Selenomonas ruminantium AC2024,Downstream,8112.5,0.999631079,2.24E+02,-0.112913223,0.001251541,2.80E-01,32,782,Intragenic,40008,0.621406104,139.1949673,0.006724327,0.735012537,164.6428083,33,2503,Upstream,8540.5,0.9999981,223.9995744,-0.129062905,0.0000257,0.0057568,32,1025 Hirschia baltica ATCC 49814,Downstream,4498,0.88713916,1.99E+02,-0.045589501,0.160748025,3.60E+01,12,936,Intragenic,16069.5,0.830067002,185.9350084,-0.01741996,0.324720669,72.73742986,12,3186,Upstream,7164.5,0.935150579,209.4737297,-0.036113645,0.147505215,33.04116816,12,1598 Marinithermus hydrothermalis DSM 14884,Downstream,13584.5,0.691370601,1.55E+02,-0.036680097,0.474153033,1.06E+02,99,284,Intragenic,84326.5,0.999843,223.964832,-0.063932095,0.002328624,0.521611776,99,2167,Upstream,22524.5,0.97913327,219.3258525,-0.071124886,0.075364453,16.88163747,98,528 Sulfurimonas denitrificans DSM 1251,Downstream,513.5,0.920554546,2.06E+02,-0.074262502,0.179035993,4.01E+01,5,324,Intragenic,4222,0.788153246,176.5463271,-0.022109697,0.307306991,68.83676598,5,2129,Upstream,821.5,0.962953281,215.7015349,-0.063580663,0.114633417,25.67788541,5,612 Thiomicrospira kuenenii DSM 12350,Downstream,1000,0.89812582,2.01E+02,-0.049574397,0.225696927,5.06E+01,5,594,Intragenic,4217,0.822257279,184.1856305,-0.036388057,0.086440599,19.36269418,5,2216,Upstream,1185,0.976552306,218.7477165,-0.059525786,0.062366926,13.97019142,5,976 Methylobacterium sp. 10,Downstream,94556.5,0.776429614,1.74E+02,-0.001830348,0.934412502,2.09E+02,103,1921,Intragenic,203388,0.977741345,219.0140613,0.01880488,0.206017825,46.1479928,104,4420,Upstream,120329,0.982818781,220.1514069,-0.002245721,0.905567899,202.8472094,102,2691 Ralstonia solanacearum GMI1000 ,Downstream,224386.5,0.998326558,2.24E+02,-0.094804685,3.00E-05,6.72E-03,309,1623,Intragenic,554854,1,224,-0.107990293,8.85E-15,1.98E-12,309,4820,Upstream,354567.5,0.741109222,166.0084657,-0.022812268,0.239801544,53.71554586,309,2348 Treponema denticola ATCC 35405,Downstream,4763,0.893725553,2.00E+02,-0.052767484,0.212066645,4.75E+01,21,540,Intragenic,24613,0.864371053,193.6191159,-0.000456211,0.980942803,219.7311879,21,2723,Upstream,6722,0.986141498,220.8956956,-0.060862229,0.066332327,14.85844125,21,890 Echinicola vietnamensis DSM 17526,Downstream,163510.5,0.746525147,1.67E+02,-0.060157225,0.005964857,1.34E+00,176,1912,Intragenic,304665.5,0.999999632,223.9999176,-0.05126031,0.000496016,0.111107584,176,4437,Upstream,160467,0.999992273,223.9982692,-0.081242648,0.0000592,0.0132608,176,2262 Anoxybacillus flavithermus WK1,Downstream,92494,0.753644289,1.69E+02,-0.040012038,0.220593863,4.94E+01,295,644,Intragenic,298086.5,1,224,-0.075817229,0.0000276,0.0061824,306,2745,Upstream,132398.5,0.999983882,223.9963896,-0.062007564,0.022753998,5.096895552,298,1051 Pseudomonas stutzeri RCH2,Downstream,18256,0.784871061,1.76E+02,-0.046645457,0.087143195,1.95E+01,30,1316,Intragenic,43528,0.998398368,223.6412344,-0.042320144,0.005814537,1.302456288,30,4216,Upstream,25082.5,0.979292686,219.3615617,-0.045661295,0.034377068,7.700463232,30,2117 Algoriphagus marincola HL-49,Downstream,36083,0.880462858,1.97E+02,-0.053647763,0.075846905,1.70E+01,77,1019,Intragenic,130312,0.884794584,198.1939868,-0.008937565,0.584031708,130.8231026,77,3678,Upstream,41159,0.99999384,223.9986202,-0.100631345,0.0000507,0.0113568,76,1540 Desulfobacca acetoxidans DSM 11109,Downstream,24532,0.9803882,2.20E+02,-0.061468273,0.030772035,6.89E+00,50,1185,Intragenic,57140,0.999115912,223.8019643,-0.05064675,0.006114008,1.369537792,53,2876,Upstream,34360.5,0.794004975,177.8571144,-0.015054871,0.560673827,125.5909372,51,1445 Spirochaeta thermophila DSM 6578,Downstream,30638.5,0.780529261,1.75E+02,-0.062521026,0.156551188,3.51E+01,206,309,Intragenic,170265.5,0.999999999,223.9999998,0.030041229,0.139159029,31.1716225,206,2219,Upstream,51895,0.999837824,223.9636726,-0.068160553,0.052924355,11.85505552,206,601 Oceanicola sp. HL-35,Downstream,175105.5,0.787873765,1.76E+02,-0.053648482,0.043544296,9.75E+00,333,1083,Intragenic,439505.5,1,224,-0.07018276,0.00000329,0.00073696,336,4049,Upstream,241267.5,0.999907083,223.9791866,-0.062997879,0.004670077,1.046097248,329,1686 Syntrophobotulus glycolicus DSM 8271,Downstream,44042.5,0.924937239,2.07E+02,-0.053456468,0.062607342,1.40E+01,86,1128,Intragenic,136567,0.865555088,193.8843397,0.032057415,0.063680546,14.2644423,90,3257,Upstream,41378.5,0.999996595,223.9992373,-0.093791911,0.000397803,0.089107872,87,1335 Syntrophothermus lipocalidus DSM 12680,Downstream,8156.5,0.835586059,1.87E+02,-0.030041766,0.38795033,8.69E+01,23,805,Intragenic,18984,0.998307326,223.620841,-0.03494794,0.091899416,20.58546918,25,2302,Upstream,9311.5,0.982576418,220.0971176,-0.043623963,0.165112308,36.98515699,25,989 Bifidobacterium longum subsp. infantis ATCC 15697,Downstream,76425.5,0.99999834,2.24E+02,-0.117138952,2.88E-05,6.45E-03,179,1090,Intragenic,210173.5,0.835946856,187.2520957,0.042641405,0.029406011,6.586946464,181,2428,Upstream,89573,0.999992439,223.9983063,-0.088996608,0.000713112,0.159737088,177,1266 Clostridium sp. 12(A),Downstream,29260,0.848273566,1.90E+02,-0.048537824,0.068643927,1.54E+01,47,1361,Intragenic,62974,0.999999858,223.9999682,-0.08048073,0.000000187,0.000041888,52,4131,Upstream,33718,0.999866962,223.9701995,-0.078936043,0.000587123,0.131515552,52,1841 Spirochaeta africana DSM 8902,Downstream,16195.5,0.876355819,1.96E+02,0.03874442,0.358820834,8.04E+01,72,491,Intragenic,83011.5,0.994586889,222.7874631,0.079614905,0.0000225,0.00504,73,2755,Upstream,25579,0.979570242,219.4237342,0.040772603,0.220942081,49.49102614,72,831 Hippea alviniae EP5-r,Downstream,398.5,0.959151659,2.15E+02,-0.121231376,0.093925255,2.10E+01,7,185,Intragenic,5835,0.905916379,202.9252689,-0.043125641,0.071533416,16.02348518,9,1738,Upstream,585,0.992327311,222.2813177,-0.109377209,0.036471577,8.169633248,7,359 Aminobacterium colombiense DSM 12261,Downstream,914.5,0.912090381,2.04E+02,-0.060066949,0.243384208,5.45E+01,7,372,Intragenic,3517.5,0.983626314,220.3322943,-0.027607889,0.230023251,51.52520822,7,1885,Upstream,1299.5,0.96521848,216.2089395,-0.052674859,0.188815362,42.29464109,7,617 Neisseria gonorrhoeae FA 1090,Downstream,23908,0.968092734,2.17E+02,-0.048818646,0.144929164,3.25E+01,67,826,Intragenic,44873,0.999988108,223.9973362,-0.075558365,0.00090762,0.20330688,69,1856,Upstream,30371.5,0.898240555,201.2058843,-0.025151243,0.418242205,93.68625392,69,969 Leptolyngbya sp. PCC 6406,Downstream,525024,0.872153003,1.95E+02,-0.07730494,1.63E-05,3.65E-03,402,2701,Intragenic,418035,1,224,-0.218187554,1.07E-56,2.40E-54,411,4753,Upstream,474043,1,224,-0.100172336,1.45E-09,3.25E-07,395,3236 Ruminococcus gnavus AGR2154,Downstream,162366.5,0.998306564,2.24E+02,-0.104919707,9.00E-05,2.02E-02,349,1039,Intragenic,594568.5,0.879201337,196.9410995,0.041465457,0.010394784,2.328431616,357,3461,Upstream,169391.5,1,224,-0.188704488,2.93E-15,6.56E-13,356,1365 Pseudobutyrivibrio ruminis HUN009,Downstream,239,0.945867211,2.12E+02,-0.050212407,0.185786191,4.16E+01,2,694,Intragenic,666.5,0.963783973,215.88761,-0.03681121,0.065513659,14.67505962,2,2502,Upstream,174.5,0.976868471,218.8185375,-0.054585489,0.09405932,21.06928768,2,940 Teredinibacter sp. 991H.S.0a.06,Downstream,56528.5,0.90754554,2.03E+02,-0.010798035,0.65328482,1.46E+02,74,1659,Intragenic,141213,0.996107652,223.128114,-0.010894916,0.478125266,107.1000596,81,4160,Upstream,63888,0.990322263,221.8321869,-0.014908923,0.494705522,110.8140369,74,2026 Desulfurobacterium sp. TC5-1,Downstream,1214,0.988292333,2.21E+02,-0.143430406,0.034721741,7.78E+00,18,199,Intragenic,11974,0.924596207,207.1095504,-0.029626946,0.225691012,50.55478669,18,1656,Upstream,2146.5,0.995324015,222.9525794,-0.128025136,0.011176793,2.503601632,18,374 Sphingomonas melonis C3,Downstream,51768.5,0.932802317,2.09E+02,-0.024082191,0.376264143,8.43E+01,90,1262,Intragenic,139817,0.997529429,223.4465921,0.072916101,0.00000963,0.00215712,94,3582,Upstream,54501,0.999550516,223.8993156,-0.00813868,0.742579579,166.3378257,89,1542 Zymomonas mobilis subsp. pomaceae ATCC 29192,Downstream,7504.5,0.978122256,2.19E+02,-0.082471731,0.024283653,5.44E+00,27,719,Intragenic,19329,0.952901839,213.4500119,-0.056543327,0.016764562,3.755261888,27,1762,Upstream,8666.5,0.999167724,223.8135702,-0.102068898,0.001090958,0.244374592,27,994 Xanthobacter sp. 91,Downstream,15240,0.954598956,2.14E+02,-0.020554598,0.398414917,8.92E+01,23,1667,Intragenic,38276,0.998019832,223.5564424,-0.015431632,0.282113565,63.19343856,24,4836,Upstream,22114.5,0.978348811,219.1501337,-0.015286993,0.438727887,98.27504669,23,2545 Cohnella panacarvi Gsoil 349,Downstream,59351.5,0.941222204,2.11E+02,-0.062395274,0.012142175,2.72E+00,86,1529,Intragenic,164300,0.998067971,223.5672255,-0.050664253,0.000801371,0.179507104,93,4282,Upstream,78336,0.992975558,222.426525,-0.065134709,0.002416858,0.541376192,89,2078 Flexibacter litoralis DSM 6794,Downstream,273976.5,0.94971191,2.13E+02,-0.054664222,0.007270856,1.63E+00,273,2137,Intragenic,442850.5,0.999999937,223.9999859,-0.060216691,0.000106426,0.023839424,283,3854,Upstream,315162.5,0.99999892,223.9997581,-0.08797147,0.0000013,0.0002912,278,2739 Exiguobacterium sp. GIC31,Downstream,29446,0.999959987,2.24E+02,-0.137356417,4.48E-05,1.00E-02,100,777,Intragenic,141909,0.949978539,212.7951927,-0.026797491,0.140087235,31.37954064,107,2926,Upstream,43488,1,224,-0.166210494,2.37E-10,5.31E-08,105,1330 Saccharomonospora viridis DSM 43017,Downstream,7104.5,0.96909754,2.17E+02,-0.056463332,0.039580399,8.87E+00,15,1314,Intragenic,17789.5,0.994658768,222.803564,-0.046922485,0.003594174,0.805094976,15,3834,Upstream,8964.5,0.992042227,222.2174588,-0.054189243,0.018628635,4.17281424,15,1870 Pelobacter seleniigenes DSM 18267,Downstream,65545,0.977971768,2.19E+02,-0.055410342,0.018919779,4.24E+00,88,1706,Intragenic,171457,0.983368248,220.2744876,-0.006975465,0.640893476,143.5601386,90,4384,Upstream,64743,0.999999918,223.9999816,-0.096332282,0.00000407,0.00091168,88,2192 Desulfovibrio cf. magneticus IFRC170,Downstream,28052,0.971265881,2.18E+02,-0.043824304,0.056730334,1.27E+01,37,1854,Intragenic,36536,0.999999997,223.9999993,-0.094340194,1.35E-09,3.02E-07,39,4073,Upstream,29553.5,0.993355136,222.5115505,-0.05107113,0.018386594,4.118597056,37,2094 Lachnobacterium bovis strain AE2004,Downstream,47885,0.965203548,2.16E+02,-0.039329316,0.1726348,3.87E+01,97,1107,Intragenic,80705.5,0.999999945,223.9999877,-0.033225808,0.094422676,21.15067942,97,2438,Upstream,39742,0.999999776,223.9999498,-0.071850578,0.010128332,2.268746368,97,1183 Exiguobacterium oxidotolerans JCM 12280,Downstream,22807,0.999998383,2.24E+02,-0.131873844,9.97E-06,2.23E-03,66,1049,Intragenic,93527.5,0.966493658,216.4945794,-0.020972447,0.247295419,55.39417386,72,2973,Upstream,30161.5,0.999999998,223.9999996,-0.140360819,4.95E-08,0.000011088,72,1425 Flexistipes sinusarabici DSM 4947,Downstream,107323.5,0.97183734,2.18E+02,-0.077788902,0.014456783,3.24E+00,381,607,Intragenic,324633,1,224,-0.074256403,0.000157585,0.03529904,398,2187,Upstream,134701.5,0.995325674,222.952951,-0.034903435,0.236721386,53.02559046,391,760 Lachnospiraceae bacterium AC2031,Downstream,12144,0.972655061,2.18E+02,-0.05786148,0.084492618,1.89E+01,35,855,Intragenic,28121,0.999984794,223.9965939,-0.067079524,0.00042424,0.09502976,35,2722,Upstream,12102.5,0.999648379,223.9212369,-0.077485648,0.00970875,2.17476,34,1079 Lachnospiraceae bacterium AC2012,Downstream,4400.5,0.976525453,2.19E+02,-0.084352068,0.026603214,5.96E+00,18,673,Intragenic,10690,0.999744952,223.9428692,-0.073702448,0.000428135,0.09590224,18,2262,Upstream,4235.5,0.999689894,223.9305363,-0.10435896,0.001648516,0.369267584,18,889 Shewanella woodyi ATCC 51908,Downstream,95114,0.980138753,2.20E+02,-0.063937313,0.003030958,6.79E-01,105,2043,Intragenic,96024,1,224,-0.163084221,5.35E-31,1.20E-28,105,4870,Upstream,103609,0.999999982,223.999996,-0.079451205,0.0000139,0.0031136,105,2880 Joostella marina DSM 19592,Downstream,124619,0.981359115,2.20E+02,-0.021290306,0.371775337,8.33E+01,173,1589,Intragenic,245167.5,0.99999999,223.9999978,0.025308951,0.111248032,24.91955917,173,3788,Upstream,119439,0.999999997,223.9999993,-0.033643626,0.12753442,28.56771008,173,1880 Enterococcus faecalis 68A,Downstream,7257,0.990977392,2.22E+02,-0.083515849,0.007918417,1.77E+00,21,989,Intragenic,22863,0.994173272,222.6948129,-0.044104697,0.024216503,5.424496672,25,2586,Upstream,7731.5,0.999201549,223.821147,-0.098856429,0.000302222,0.067697728,20,1312 Rhizobium etli CIAT 652,Downstream,154059,0.99759605,2.23E+02,-0.02959674,0.152534734,3.42E+01,163,2175,Intragenic,453673.5,0.986854453,221.0553975,0.085279655,2.54E-11,5.69E-09,170,5929,Upstream,200707.5,0.999999568,223.9999032,-0.032241973,0.061934596,13.8733495,163,3190 Leeuwenhoekiella sp. Hel_I_48,Downstream,12829.5,0.986234422,2.21E+02,-0.066133969,0.033559897,7.52E+00,33,1000,Intragenic,40725.5,0.999121811,223.8032857,-0.043229656,0.009085195,2.03508368,33,3608,Upstream,14989.5,0.999988811,223.9974937,-0.090873092,0.000241251,0.054040224,33,1595 Methylobacterium extorquens AM1,Downstream,625174.5,0.988646051,2.21E+02,-0.060798909,0.000834103,1.87E-01,537,2480,Intragenic,1551502,0.999963268,223.991772,-0.004053892,0.741173067,166.022767,568,6073,Upstream,719068,1,224,-0.083241591,0.000000139,0.000031136,518,3474 Exiguobacterium antarcticum DSM 14480,Downstream,86123.5,0.999999993,2.24E+02,-0.146314011,3.53E-07,7.91E-05,234,967,Intragenic,337319.5,0.991758694,222.1539475,0.054953191,0.00146091,0.32724384,239,3112,Upstream,102977.5,1,224,-0.189064899,7.58E-15,1.70E-12,233,1430 Acidobacteriaceae bacterium TAA166,Downstream,103192.5,0.99200708,2.22E+02,-0.055057212,0.005400995,1.21E+00,98,2454,Intragenic,198651.5,0.999942697,223.9871641,-0.026879595,0.053308845,11.94118128,101,5068,Upstream,93197.5,0.999999924,223.999983,-0.080866818,0.00000713,0.00159712,92,2983 Sulfurospirillum barnesii SES-3,Downstream,3483.5,0.99931615,2.24E+02,-0.155244676,0.003020865,6.77E-01,32,331,Intragenic,28941,0.995785387,223.0559267,-0.022939472,0.250431458,56.09664659,32,2480,Upstream,5769,0.999999272,223.9998369,-0.150057903,0.0000339,0.0075936,32,725 Ruminococcus flavefaciens AE3010,Downstream,10393.5,0.999994577,2.24E+02,-0.108192281,0.000151043,3.38E-02,32,1190,Intragenic,42859.5,0.995235457,222.9327424,-0.030275004,0.091086401,20.40335382,37,3079,Upstream,13301.5,0.999999563,223.9999021,-0.110158675,0.0000175,0.00392,35,1478 Acetobacterium woodii DSM 1030,Downstream,67517.5,0.999771007,2.24E+02,-0.011975743,0.629308279,1.41E+02,111,1516,Intragenic,169310,0.995493066,222.9904468,0.072858948,0.0000106,0.0023744,112,3535,Upstream,78562.5,0.999980757,223.9956896,0.009466792,0.677126979,151.6764433,112,1825 Thiomicrospira crunogena XCL-2,Downstream,3329.5,0.999590468,2.24E+02,-0.131718586,0.001069894,2.40E-01,20,594,Intragenic,14399,0.99701674,223.3317498,-0.088911781,0.0000233,0.0052192,20,2238,Upstream,3539,0.999999068,223.9997912,-0.155121373,0.00000142,0.00031808,20,937 Alteromonadaceae bacterium Bs12,Downstream,249864.5,0.997939267,2.24E+02,-0.062488953,0.003747831,8.40E-01,301,1849,Intragenic,587392.5,0.999651838,223.9220117,0.02478652,0.091093622,20.40497133,306,4342,Upstream,279658.5,1,224,-0.091348419,0.00000248,0.00055552,306,2344 Butyrivibrio sp. FCS014,Downstream,46040,0.998639073,2.24E+02,-0.054742377,0.058940158,1.32E+01,103,1088,Intragenic,149791,0.999847883,223.9659258,-0.02735511,0.102846704,23.0376617,109,3448,Upstream,43374,1,224,-0.088245274,0.000761923,0.170670752,103,1349 Meiothermus silvanus DSM 9946,Downstream,216922,0.999420352,2.24E+02,-0.103986982,5.75E-05,1.29E-02,477,1014,Intragenic,705677.5,1,224,-0.087569147,4.42E-08,9.90E-06,528,3366,Upstream,290317,0.999119322,223.8027281,-0.058807478,0.012580933,2.818128992,490,1310 Bacterium JKG1,Downstream,23245,0.999009278,2.24E+02,-0.07709626,0.007542605,1.69E+00,54,1146,Intragenic,36481,1,224,-0.181806853,5.86E-30,1.31E-27,57,3792,Upstream,35241.5,0.999820021,223.9596847,-0.067544789,0.003747246,0.839383104,55,1785 Coraliomargarita akajimensis DSM 45221,Downstream,4124.5,0.999719871,2.24E+02,-0.090584455,0.002068578,4.63E-01,15,1139,Intragenic,11657,0.99946234,223.8795642,-0.081116435,0.00000715,0.0016016,15,3040,Upstream,5002.5,0.999860803,223.9688199,-0.090746377,0.000473446,0.106051904,15,1465 Thermobacillus composti KWC4,Downstream,223596.5,0.999265266,2.24E+02,-0.099803547,3.15E-05,7.06E-03,367,1366,Intragenic,588639.5,0.999999717,223.9999366,-0.054333385,0.000457899,0.102569376,369,3787,Upstream,246829,1,224,-0.184598202,5.80E-19,1.30E-16,368,1917 Cellulomonas sp. KRMCY2,Downstream,92903.5,0.99932954,2.24E+02,-0.086387731,0.001194782,2.68E-01,178,1226,Intragenic,235680.5,1,224,-0.137222176,5.09E-19,1.14E-16,181,3998,Upstream,139254,0.999975835,223.994587,-0.084485097,0.000103703,0.023229472,177,1929 Pediococcus acidilactici AGR20,Downstream,18391.5,1,2.24E+02,-0.199102096,5.75E-09,1.29E-06,84,757,Intragenic,58601,0.999627936,223.9166577,-0.072505595,0.001719081,0.385074144,84,1783,Upstream,15660,1,224,-0.244471409,2.29E-14,5.13E-12,84,864 Lactococcus lactis lactis 511,Downstream,8678.5,0.999979175,2.24E+02,-0.105326914,0.000777074,1.74E-01,31,984,Intragenic,23499,0.999776586,223.9499553,-0.018948173,0.351078473,78.64157795,31,2393,Upstream,9470.5,0.999999719,223.9999371,-0.111255466,0.0000517,0.0115808,31,1287 Clostridium difficile 630,Downstream,20573.5,0.9998623,2.24E+02,-0.051856298,0.025048423,5.61E+00,35,1832,Intragenic,43122,0.999985289,223.9967047,-0.066478895,0.0000432,0.0096768,38,3741,Upstream,22225,0.999916062,223.9811979,-0.073687847,0.001027262,0.230106688,36,1946 Geopsychrobacter electrodiphilus DSM 16401,Downstream,35777,0.999774902,2.24E+02,-0.090612008,0.000661012,1.48E-01,71,1338,Intragenic,100402,0.999997053,223.9993399,-0.088337559,3.75E-08,0.0000084,76,3791,Upstream,42672,0.999999814,223.9999583,-0.116295443,0.000000819,0.000183456,76,1712 Clostridium difficile 630,Downstream,20385.5,0.999890364,2.24E+02,-0.074198488,0.001335207,2.99E-01,35,1832,Intragenic,43122,0.999985289,223.9967047,-0.066478895,0.0000432,0.0096768,38,3741,Upstream,22225,0.999916062,223.9811979,-0.073687847,0.001027262,0.230106688,36,1946 Meiothermus ruber DSM 1279,Downstream,17577,0.999845886,2.24E+02,-0.136719133,0.000172919,3.87E-02,70,680,Intragenic,54086,1,224,-0.168762734,5.34E-21,1.20E-18,71,2991,Upstream,22738,0.999999961,223.9999913,-0.15694248,0.000000099,0.000022176,69,1072 Clostridium thermocellum DSM 1313,Downstream,107791.5,0.999878031,2.24E+02,-0.103824096,3.72E-05,8.33E-03,185,1387,Intragenic,161567,1,224,-0.133851986,5.07E-14,1.14E-11,186,2953,Upstream,115405.5,0.999999958,223.9999906,-0.092078578,0.0000821,0.0183904,185,1639 Microbacterium sp. KROCY2,Downstream,20367.5,0.999954777,2.24E+02,-0.112323851,0.000301865,6.76E-02,60,971,Intragenic,35755.5,1,224,-0.150479296,1.10E-13,2.46E-11,60,2352,Upstream,24828.5,0.999999549,223.999899,-0.123056749,0.00000444,0.00099456,60,1323 Bryobacter aggregatus MPL3,Downstream,61939.5,0.999979722,2.24E+02,-0.130236899,1.94E-05,4.35E-03,172,897,Intragenic,327963,1,224,-0.084928617,1.23E-09,2.76E-07,183,4920,Upstream,86521,1,224,-0.163463908,5.96E-11,1.34E-08,180,1404 Methylobacter tundripaludum 21/22,Downstream,105349,0.999996204,2.24E+02,-0.088659326,0.000109449,2.45E-02,154,1745,Intragenic,205150,1,224,-0.072478165,0.00000323,0.00072352,156,3962,Upstream,92883,1,224,-0.142077675,3.57E-11,8.00E-09,155,1997 Caldithrix abyssi DSM 13497,Downstream,162500.5,0.999996224,2.24E+02,-0.112873594,4.63E-06,1.04E-03,289,1350,Intragenic,421912.5,1,224,-0.088728884,0.000000017,0.000003808,304,3723,Upstream,149725,1,224,-0.195334428,2.97E-17,6.65E-15,294,1543 Nitratifractor salsuginis DSM 16511,Downstream,6167,1,2.24E+02,-0.215662897,2.36E-08,5.29E-06,45,612,Intragenic,30923,0.999996479,223.9992113,-0.090416091,0.0000303,0.0067872,48,2074,Upstream,6022.5,1,224,-0.259607666,3.33E-14,7.46E-12,47,780 Desulfospira joergensenii DSM 10085,Downstream,115263,0.999998319,2.24E+02,-0.09951546,1.19E-05,2.67E-03,167,1763,Intragenic,236695,1,224,-0.130176154,1.35E-22,3.02E-20,168,5433,Upstream,130608.5,1,224,-0.120635495,6.16E-10,1.38E-07,164,2449 Alicyclobacillus macrosporangiidus CPP55,Downstream,113485.5,0.999998856,2.24E+02,-0.094671254,0.000105782,2.37E-02,194,1478,Intragenic,211503.5,1,224,-0.120172786,3.17E-14,7.10E-12,196,3768,Upstream,132750.5,1,224,-0.092693113,0.0000246,0.0055104,194,1871 Sinorhizobium medicae WSM1115,Downstream,286853.5,0.999999756,2.24E+02,-0.100335385,1.65E-07,3.70E-05,280,2431,Intragenic,503341.5,1,224,-0.069636274,1.21E-08,2.71E-06,287,6396,Upstream,293077,1,224,-0.119271037,9.58E-13,2.15E-10,278,3279 Exiguobacterium acetylicum DSM 20416,Downstream,29925.5,1,2.24E+02,-0.100473816,0.001132221,2.54E-01,112,935,Intragenic,136300.5,0.999999949,223.9999886,0.066248761,0.000120723,0.027041952,118,3245,Upstream,38893,1,224,-0.121017544,0.00000113,0.00025312,114,1494 Clostridium thermocellum ATCC 27405,Downstream,172229,1,2.24E+02,-0.170990609,2.08E-13,4.66E-11,341,1479,Intragenic,360819,1,224,-0.155162448,1.88E-20,4.21E-18,343,3185,Upstream,210045.5,1,224,-0.15075718,4.76E-12,1.07E-09,343,1738 Thiomicrospira sp. MA2-6,Downstream,2822.5,1,2.24E+02,-0.255767076,7.86E-13,1.76E-10,34,727,Intragenic,10638,1,224,-0.166476377,6.56E-17,1.47E-14,34,2452,Upstream,2298.5,1,224,-0.271595628,1.21E-20,2.71E-18,33,1102 Verrucomicrobia bacterium LP2A,Downstream,22094,1,2.24E+02,-0.326609351,7.88E-20,1.77E-17,125,614,Intragenic,87408,1,224,-0.204980724,4.54E-24,1.02E-21,137,2251,Upstream,39596.5,1,224,-0.255763638,2.81E-17,6.29E-15,129,930