Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage

Supplemental Data

• Supplemental Figures (.pdf, 858 KB) - Supplemental Figure 1. CSB-dependent recruitment of Elongin A (A) and CUL5 (B) to localized DNA damage in CS1ANsv cells. Supplemental Figure 2. AP-FRET between wild type or mutant Halo-Elongin A labeled with TMRDirect and GFP-CSB (A) or Halo-Elongin A labeled with rhodamine 110 and mCherry-CUL5 (C). B. Kinetics of recruitment of wild type and mutant Halo-Elongin A.