mutation likelihood blosum62 nt_mutation pclass res sres isen neu RES SCORE (RS) Normalized RS CONSERVATION TCGA D855A 0.0008582 -2 [G[A>C]T] Strong resistance 0.389 0.433 0.132 0.046 0.367 1.0 3.19 NO L792P 0.004031 -3 [C[T>C]C] Strong resistance 0.208 0.592 0.152 0.048 0.363 0.990629175008 -0.47 NO G719V 0.0023037 -3 [G[G>T]C] Strong resistance 0.302 0.466 0.191 0.042 0.312 0.881970656942 0.65 NO G796V 0.0023037 -3 [G[G>T]C] Strong resistance 0.282 0.477 0.199 0.042 0.306 0.866974803707 0.39 NO M793L 0.0064421 2 [C[A>T]T] Strong resistance 0.205 0.544 0.209 0.043 0.302 0.858865295992 -0.1 NO M793L 0.003103 2 [C[A>C]T] Strong resistance 0.205 0.544 0.209 0.043 0.302 0.858865295992 -0.1 NO G719S 0.0075322 0 [G[G>A]G] Resistance 0.574 0.212 0.174 0.04 0.301 0.858212098298 0.65 NO T725P 0.0013146 -1 [C[A>C]C] Resistance 0.389 0.374 0.169 0.069 0.299 0.853601726988 -0.04 NO H835Y 0.0099217 2 [G[C>T]A] Strong resistance 0.259 0.486 0.17 0.085 0.297 0.848047819628 2.95 NO L718P 0.0080975 -3 [C[T>C]G] Strong resistance 0.262 0.485 0.202 0.051 0.294 0.842209466802 0.71 NO M793R 0.00192 -1 [A[T>G]G] Strong resistance 0.211 0.527 0.203 0.058 0.291 0.836363132087 -0.1 NO M793K 0.0063649 -1 [A[T>A]G] Strong resistance 0.225 0.505 0.213 0.057 0.279 0.809144136879 -0.1 NO G796S 0.0101281 0 [C[G>A]G] Resistance 0.483 0.273 0.204 0.039 0.278 0.807406141292 0.39 NO L798P 0.004031 -3 [C[T>C]C] Strong resistance 0.257 0.458 0.18 0.104 0.264 0.777627397503 -0.55 NO T854P 0.0013146 -1 [C[A>C]C] Strong resistance 0.264 0.452 0.202 0.082 0.261 0.770214924493 1.35 NO L792V 0.0035541 1 [G[C>G]T] Strong resistance 0.267 0.449 0.246 0.038 0.254 0.75692028494 -0.47 NO D855N 0.0118934 1 [A[G>A]A] Resistance 0.365 0.357 0.214 0.064 0.253 0.754586552254 3.19 NO L792H 0.0055481 -3 [C[T>A]C] Strong resistance 0.289 0.424 0.218 0.069 0.252 0.752614633405 -0.47 NO G721A 0.0035541 0 [G[G>C]T] Resistance 0.478 0.248 0.174 0.1 0.25 0.746658921294 0.33 NO R841S 0.0037355 -1 [G[G>C]A] Resistance 0.446 0.27 0.134 0.15 0.248 0.742716564116 1.72 NO R841S 0.003034 -1 [G[G>T]A] Resistance 0.446 0.27 0.134 0.15 0.248 0.742716564116 1.72 NO G796A 0.0044927 0 [G[G>C]C] Resistance 0.424 0.301 0.235 0.04 0.247 0.741015305331 0.39 NO G721V 0.00249 -3 [G[G>T]T] Strong resistance 0.316 0.391 0.186 0.108 0.247 0.740894619474 0.33 NO D855G 0.0048614 -1 [G[A>G]T] Strong resistance 0.343 0.369 0.205 0.083 0.247 0.740716992664 3.19 NO T725A 0.0039845 0 [C[A>G]C] Resistance 0.448 0.274 0.191 0.087 0.247 0.739886430551 -0.04 NO F856I 0.0043684 0 [T[T>A]T] Resistance 0.434 0.282 0.181 0.104 0.243 0.731470501823 2.89 NO G721S 0.0101281 0 [C[G>A]G] Resistance 0.498 0.22 0.176 0.106 0.238 0.722436625285 0.33 NO L792F 0.0095735 0 [G[C>T]T] Strong resistance 0.307 0.395 0.23 0.068 0.238 0.720704045819 -0.47 NO R841K 0.0116451 2 [A[G>A]G] Strong resistance 0.319 0.373 0.146 0.162 0.236 0.717632454929 1.72 NO C775W 0.004516 -2 [G[C>G]C] Strong resistance 0.316 0.376 0.182 0.126 0.233 0.709813477199 -0.2 NO S720A 0.0013611 1 [C[T>G]C] Resistance 0.472 0.234 0.194 0.1 0.227 0.697221733137 -0.1 NO T854A 0.0039845 0 [C[A>G]C] Strong resistance 0.317 0.374 0.218 0.091 0.226 0.696268292799 1.35 NO H835Q 0.0036835 0 [A[C>G]C] Resistance 0.387 0.31 0.2 0.103 0.226 0.69562939747 2.95 NO H835Q 0.0133679 0 [A[C>A]C] Resistance 0.387 0.31 0.2 0.103 0.226 0.69562939747 2.95 NO L844P 0.0080975 -3 [C[T>C]G] Strong resistance 0.164 0.512 0.243 0.081 0.225 0.694082355695 1.51 NO I853M 0.0105033 1 [T[C>G]A] Resistance 0.408 0.289 0.194 0.108 0.225 0.69265799042 0.76 NO T725M 0.0116509 -1 [A[C>T]G] Resistance 0.433 0.269 0.215 0.083 0.224 0.691759975314 -0.04 NO G719R 0.0024354 -2 [G[G>C]G] Resistance 0.459 0.247 0.222 0.073 0.224 0.690831805826 0.65 NO G779S 0.0075322 0 [G[G>A]G] Resistance 0.454 0.248 0.203 0.095 0.223 0.689248076844 -0.18 NO G796R 0.0028217 -2 [C[G>C]G] Resistance 0.397 0.303 0.242 0.059 0.223 0.688375752938 0.39 NO V726M 0.0086368 1 [G[G>A]T] Resistance 0.423 0.28 0.246 0.051 0.222 0.687320442137 0.68 NO V726G 0.0021293 -3 [G[T>G]G] Resistance 0.353 0.341 0.241 0.065 0.222 0.686766122815 0.68 NO C775F 0.0046165 -2 [T[G>T]C] Resistance 0.344 0.342 0.189 0.125 0.221 0.685803317716 -0.2 NO V845M 0.0086368 1 [G[G>A]T] Resistance 0.392 0.304 0.228 0.077 0.22 0.683693527626 -0.18 NO L792I 0.0115672 2 [G[C>A]T] Strong resistance 0.311 0.378 0.263 0.048 0.219 0.680104651154 -0.47 NO Q787L 0.0144798 -2 [C[A>T]G] Strong resistance 0.257 0.421 0.237 0.085 0.217 0.67672964953 -0.63 NO V726A 0.0048239 0 [G[T>C]G] Resistance 0.348 0.34 0.247 0.064 0.216 0.674115462615 0.68 NO Y727C 0.0050166 -2 [T[A>G]T] Strong resistance 0.258 0.417 0.236 0.088 0.214 0.669931603877 0.06 NO T725K 0.0070042 -1 [A[C>A]G] Resistance 0.424 0.268 0.222 0.085 0.214 0.669863526246 -0.04 NO G796C 0.0006593 -3 [C[G>T]G] Resistance 0.354 0.332 0.255 0.059 0.211 0.664038630453 0.39 NO L778P 0.0080975 -3 [C[T>C]G] Strong resistance 0.279 0.392 0.211 0.117 0.211 0.663123956097 -0.18 NO R776S 0.0037534 -1 [C[C>A]G] Resistance 0.496 0.196 0.176 0.132 0.211 0.662551039071 -0.1 NO C775Y 0.0268571 -2 [T[G>A]C] Strong resistance 0.336 0.339 0.198 0.127 0.21 0.660629950455 -0.2 NO G719C 0.0006915 -3 [G[G>T]G] Resistance 0.406 0.283 0.243 0.068 0.21 0.660622045395 0.65 NO V786M 0.0143368 1 [C[G>A]T] Resistance 0.434 0.257 0.233 0.076 0.21 0.66051256727 -0.47 NO Q787R 0.0080393 1 [C[A>G]G] Strong resistance 0.284 0.391 0.245 0.08 0.209 0.659780087021 -0.63 NO E746D 0.001088 2 [A[A>C]T] Resistance 0.481 0.212 0.21 0.097 0.209 0.659615602887 -0.42 NO E746D 0.0038899 2 [A[A>T]T] Resistance 0.481 0.212 0.21 0.097 0.209 0.659615602887 -0.42 NO I780M 0.0190206 1 [T[C>G]T] Resistance 0.428 0.259 0.218 0.095 0.209 0.658076806783 -0.28 NO D855E 0.0040936 2 [A[T>A]T] Resistance 0.439 0.242 0.17 0.149 0.207 0.655250066775 3.19 NO D855E 0.001088 2 [A[T>G]T] Resistance 0.439 0.242 0.17 0.149 0.207 0.655250066775 3.19 NO E746K 0.0099217 1 [G[G>A]A] Resistance 0.455 0.231 0.212 0.102 0.206 0.651489076518 -0.42 NO G719D 0.0082777 -1 [G[G>A]C] Resistance 0.399 0.285 0.243 0.073 0.205 0.651367660071 0.65 NO T725R 0.0016772 -1 [A[C>G]G] Resistance 0.421 0.264 0.232 0.083 0.205 0.650879845091 -0.04 NO G779V 0.0023037 -3 [G[G>T]C] Strong resistance 0.233 0.43 0.239 0.097 0.204 0.648585270263 -0.18 NO I744M 0.0105033 1 [T[C>G]A] Resistance 0.375 0.304 0.239 0.082 0.204 0.647775168118 0.36 NO H835D 0.0037355 -1 [G[C>G]A] Strong resistance 0.323 0.347 0.22 0.109 0.203 0.645837536221 2.95 NO G719A 0.0044927 0 [G[G>C]C] Resistance 0.432 0.257 0.27 0.041 0.203 0.645737452292 0.65 NO Q787P 0.003325 -1 [C[A>C]G] Resistance 0.357 0.316 0.228 0.098 0.201 0.642380993741 -0.63 NO C775R 0.0048239 -3 [G[T>C]G] Resistance 0.34 0.327 0.2 0.133 0.201 0.640683329317 -0.2 NO G721R 0.0028217 -2 [C[G>C]G] Resistance 0.434 0.243 0.195 0.128 0.2 0.639921518452 0.33 NO M793V 0.0065275 1 [C[A>G]T] Strong resistance 0.215 0.449 0.294 0.042 0.2 0.639487611189 -0.1 NO R841W 0.0144798 -3 [C[A>T]G] Strong resistance 0.288 0.371 0.191 0.15 0.199 0.638068868509 1.72 NO G796D 0.0082777 -1 [G[G>A]C] Resistance 0.342 0.331 0.267 0.061 0.198 0.634215543992 0.39 NO H835R 0.0039845 0 [C[A>G]C] Strong resistance 0.32 0.344 0.221 0.115 0.197 0.632323108622 2.95 NO L718V 0.0035541 1 [G[C>G]T] Strong resistance 0.308 0.362 0.28 0.05 0.196 0.631593469453 0.71 NO S720C 0.0055991 -1 [T[C>G]C] Resistance 0.383 0.284 0.197 0.136 0.196 0.630186354824 -0.1 YES Y727H 0.006201 2 [G[T>C]A] Strong resistance 0.261 0.399 0.256 0.084 0.195 0.629215572231 0.06 NO T854R 0.0061444 -1 [A[C>G]A] Strong resistance 0.318 0.344 0.237 0.101 0.192 0.622873762048 1.35 NO F856C 0.0036054 -2 [T[T>G]T] Resistance 0.333 0.327 0.21 0.13 0.192 0.622331572585 2.89 NO L777P 0.0080975 -3 [C[T>C]G] Strong resistance 0.225 0.422 0.21 0.142 0.192 0.621708363409 -0.15 NO V742A 0.0030017 0 [G[T>C]C] Strong resistance 0.292 0.364 0.221 0.123 0.192 0.62148287736 -0.12 NO T854K 0.016752 -1 [A[C>A]A] Resistance 0.334 0.329 0.243 0.093 0.191 0.621081380582 1.35 NO D800A 9.15e-05 -2 [G[A>C]C] Resistance 0.397 0.27 0.222 0.111 0.191 0.619696183849 0.04 NO K728R 0.009702 2 [A[A>G]G] Resistance 0.405 0.263 0.235 0.097 0.189 0.616440347556 -0.34 NO A743S 0.0014191 1 [C[G>T]C] Strong resistance 0.181 0.466 0.274 0.079 0.189 0.615858722609 0.57 NO L788P 0.004031 -3 [C[T>C]C] Strong resistance 0.214 0.434 0.249 0.103 0.189 0.615127098369 0.76 NO D855Y 0.0038952 -3 [A[G>T]A] Resistance 0.355 0.31 0.259 0.076 0.188 0.614275920974 3.19 NO L798H 0.0055481 -3 [C[T>A]C] Strong resistance 0.309 0.346 0.223 0.122 0.188 0.613587953892 -0.55 NO V726E 0.0062976 -2 [G[T>A]G] Resistance 0.335 0.328 0.274 0.063 0.187 0.610510910599 0.68 NO F795I 0.0065468 0 [C[T>A]T] Resistance 0.402 0.265 0.255 0.078 0.186 0.608600102774 -0.66 NO H835P 0.0013146 -2 [C[A>C]C] Resistance 0.338 0.319 0.233 0.11 0.186 0.608447388985 2.95 NO L798F 0.0189213 0 [C[C>T]T] Strong resistance 0.312 0.339 0.224 0.125 0.184 0.604290707876 -0.55 NO V845G 0.0021293 -3 [G[T>G]G] Strong resistance 0.238 0.407 0.251 0.104 0.182 0.601730549417 -0.18 NO D800N 0.0099217 1 [G[G>A]A] Resistance 0.403 0.256 0.215 0.126 0.182 0.601224642826 0.04 NO M793I 0.005541 1 [T[G>C]C] Strong resistance 0.211 0.437 0.313 0.039 0.181 0.598057506286 -0.1 NO M793I 0.0268571 1 [T[G>A]C] Strong resistance 0.211 0.437 0.313 0.039 0.181 0.598057506286 -0.1 NO M793I 0.0046165 1 [T[G>T]C] Strong resistance 0.211 0.437 0.313 0.039 0.181 0.598057506286 -0.1 NO V742G 9.15e-05 -3 [G[T>G]C] Strong resistance 0.286 0.361 0.243 0.11 0.18 0.595837287139 -0.12 NO F856S 0.0051562 -2 [T[T>C]T] Resistance 0.378 0.273 0.197 0.152 0.179 0.594274775658 2.89 NO A840D 0.0163385 -2 [G[C>A]C] Strong resistance 0.268 0.369 0.188 0.175 0.179 0.593446366319 1.08 NO S720F 0.0436534 -2 [T[C>T]C] Resistance 0.367 0.283 0.21 0.14 0.178 0.591978823111 -0.1 NO S720Y 0.0236491 -2 [T[C>A]C] Resistance 0.363 0.286 0.211 0.14 0.177 0.58938222221 -0.1 NO C775S 0.005541 -1 [T[G>C]C] Strong resistance 0.303 0.343 0.249 0.105 0.176 0.587505750597 -0.2 NO C775S 0.0062976 -1 [G[T>A]G] Strong resistance 0.303 0.343 0.249 0.105 0.176 0.587505750597 -0.2 NO R841M 0.0005698 -1 [A[G>T]G] Resistance 0.324 0.316 0.184 0.176 0.175 0.58579085455 1.72 NO R776C 0.0113382 -3 [C[C>T]G] Resistance 0.423 0.231 0.207 0.14 0.175 0.585605129801 -0.1 NO V726L 0.00249 1 [G[G>T]T] Strong resistance 0.31 0.341 0.288 0.062 0.175 0.585494145149 0.68 NO V726L 0.0035541 1 [G[G>C]T] Strong resistance 0.31 0.341 0.288 0.062 0.175 0.585494145149 0.68 NO L798V 0.0055493 1 [C[C>G]T] Resistance 0.326 0.322 0.255 0.097 0.175 0.584965623924 -0.55 NO G721C 0.0006593 -3 [C[G>T]G] Resistance 0.379 0.27 0.222 0.128 0.174 0.583791286695 0.33 NO R841T 0.0016772 -1 [A[G>C]G] Strong resistance 0.305 0.331 0.185 0.178 0.174 0.583548831168 1.72 NO V845A 0.0048239 0 [G[T>C]G] Strong resistance 0.237 0.398 0.243 0.122 0.173 0.58194056479 -0.18 NO S720P 0.004031 -1 [C[T>C]C] Resistance 0.389 0.261 0.231 0.119 0.172 0.579186512726 -0.1 NO K846R 0.0116585 2 [A[A>G]A] Resistance 0.354 0.292 0.243 0.111 0.171 0.577021149882 -0.55 NO E758D 0.0008383 2 [A[A>C]A] Resistance 0.532 0.13 0.207 0.131 0.171 0.576592626175 0.0 NO E758D 0.0038209 2 [A[A>T]A] Resistance 0.532 0.13 0.207 0.131 0.171 0.576592626175 0.0 NO G721D 0.0086368 -1 [G[G>A]T] Resistance 0.372 0.273 0.223 0.132 0.17 0.575049756615 0.33 NO R776L 0.0014191 -2 [C[G>T]C] Resistance 0.434 0.216 0.213 0.136 0.17 0.57445349074 -0.1 NO V717M 0.0069852 1 [A[G>A]T] Resistance 0.433 0.223 0.271 0.073 0.169 0.57189100133 -0.31 NO T854I 0.0118934 -1 [A[C>T]A] Strong resistance 0.277 0.363 0.289 0.071 0.167 0.56935099343 1.35 NO M793T 0.0097428 -1 [A[T>C]G] Strong resistance 0.17 0.456 0.281 0.093 0.167 0.567674217942 -0.1 NO K716R 0.0116585 2 [A[A>G]A] Resistance 0.466 0.187 0.242 0.105 0.164 0.562792490586 -0.34 NO Y727D 0.0003896 -3 [G[T>G]A] Strong resistance 0.294 0.343 0.272 0.092 0.164 0.561873930351 0.06 NO E746A 0.0003896 -1 [G[A>C]A] Resistance 0.365 0.27 0.195 0.17 0.164 0.561787984285 -0.42 NO Y727N 0.0039837 -2 [G[T>A]A] Strong resistance 0.289 0.346 0.267 0.098 0.164 0.561017395337 0.06 NO G729V 0.003034 -3 [G[G>T]A] Strong resistance 0.246 0.381 0.248 0.125 0.163 0.559892483146 -0.5 NO G779A 0.0044927 0 [G[G>C]C] Resistance 0.326 0.312 0.26 0.102 0.163 0.559792529074 -0.18 NO E746V 0.0039837 -2 [G[A>T]A] Resistance 0.443 0.206 0.245 0.106 0.163 0.559320641576 -0.42 NO G779R 0.0024354 -2 [G[G>C]G] Resistance 0.38 0.263 0.257 0.101 0.163 0.558788430446 -0.18 NO K745R 0.009702 2 [A[A>G]G] Resistance 0.335 0.302 0.259 0.104 0.161 0.556323749025 0.76 NO I789M 0.0105033 1 [T[C>G]A] Resistance 0.358 0.279 0.244 0.118 0.161 0.55630533567 -0.23 NO C775G 0.0021293 -3 [G[T>G]G] Strong resistance 0.288 0.329 0.151 0.231 0.161 0.55457113156 -0.2 NO A840P 0.0036835 -1 [A[G>C]C] Strong resistance 0.281 0.342 0.2 0.177 0.161 0.554477590684 1.08 NO H835N 0.0162718 1 [G[C>A]A] Resistance 0.333 0.302 0.267 0.097 0.159 0.551104285334 2.95 NO M766L 0.0028478 2 [G[A>T]T] Strong resistance 0.255 0.369 0.251 0.126 0.158 0.548772885492 -0.6 NO M766L 0.0008582 2 [G[A>C]T] Strong resistance 0.255 0.369 0.251 0.126 0.158 0.548772885492 -0.6 NO L798I 0.0180802 2 [C[C>A]T] Resistance 0.339 0.295 0.26 0.107 0.157 0.547332930156 -0.55 NO A763P 0.0036835 -1 [A[G>C]C] Strong resistance 0.303 0.325 0.248 0.124 0.157 0.546692794061 -0.68 NO V845E 0.0062976 -2 [G[T>A]G] Strong resistance 0.253 0.372 0.275 0.1 0.156 0.545449156603 -0.18 NO A840V 0.0094995 0 [G[C>T]C] Strong resistance 0.23 0.385 0.217 0.168 0.156 0.544756189045 1.08 NO V742L 0.0055318 1 [C[G>C]T] Strong resistance 0.274 0.351 0.267 0.108 0.154 0.5412016695 -0.12 NO L718Q 0.0145206 -2 [C[T>A]G] Resistance 0.342 0.287 0.238 0.133 0.154 0.540685407569 0.71 NO S720T 0.0055481 1 [C[T>A]C] Resistance 0.387 0.242 0.203 0.168 0.154 0.540665609663 -0.1 NO N842T 0.0006419 0 [A[A>C]C] Strong resistance 0.258 0.355 0.197 0.19 0.154 0.540417004874 2.49 NO V786G 0.0021293 -3 [G[T>G]G] Resistance 0.357 0.275 0.258 0.11 0.154 0.540342110402 -0.47 NO K846N 0.0008383 0 [A[A>C]A] Resistance 0.32 0.306 0.26 0.113 0.152 0.535889964584 -0.55 NO K846N 0.0038209 0 [A[A>T]A] Resistance 0.32 0.306 0.26 0.113 0.152 0.535889964584 -0.55 NO D855H 0.0061444 -1 [A[G>C]A] Resistance 0.333 0.287 0.202 0.178 0.151 0.534864267877 3.19 NO E758K 0.0099217 1 [G[G>A]A] Resistance 0.463 0.171 0.2 0.167 0.15 0.532478919267 0.0 NO D761A 0.0008582 -2 [G[A>C]T] Resistance 0.487 0.153 0.232 0.129 0.15 0.531312703503 -0.63 NO D855V 0.0028478 -3 [G[A>T]T] Strong resistance 0.293 0.334 0.319 0.053 0.149 0.52903272175 3.19 NO F856Y 0.0043684 3 [T[T>A]T] Resistance 0.332 0.294 0.271 0.102 0.149 0.528584874651 2.89 NO Y801C 0.0050166 -2 [T[A>G]T] Strong resistance 0.298 0.321 0.248 0.133 0.148 0.527453761119 -0.39 NO Y727F 0.0040775 3 [T[A>T]T] Strong resistance 0.288 0.331 0.253 0.128 0.148 0.527215825096 0.06 NO V843A 0.006201 0 [G[T>C]A] Strong resistance 0.287 0.333 0.269 0.111 0.148 0.526782098023 0.55 NO G779D 0.0082777 -1 [G[G>A]C] Strong resistance 0.294 0.325 0.258 0.123 0.147 0.525496185366 -0.18 NO L718M 0.0115672 2 [G[C>A]T] Resistance 0.352 0.27 0.238 0.14 0.146 0.523683764979 0.71 NO T725S 0.0054667 1 [C[A>T]C] Resistance 0.382 0.253 0.315 0.051 0.146 0.522609515084 -0.04 NO I853N 0.0031824 -3 [A[T>A]C] Strong resistance 0.278 0.339 0.265 0.119 0.146 0.52238183324 0.76 NO V786A 0.0048239 0 [G[T>C]G] Resistance 0.337 0.283 0.251 0.128 0.145 0.520850768581 -0.47 NO K846T 0.0008383 -1 [A[A>C]A] Strong resistance 0.262 0.349 0.242 0.147 0.145 0.520727285984 -0.55 NO I744N 0.0031824 -3 [A[T>A]C] Strong resistance 0.243 0.371 0.29 0.095 0.144 0.519565580092 0.36 NO R841G 0.0080393 -2 [C[A>G]G] Strong resistance 0.271 0.339 0.234 0.156 0.144 0.518262277812 1.72 NO K745N 0.0005698 0 [A[G>T]G] Strong resistance 0.292 0.327 0.287 0.094 0.144 0.518112063459 0.76 NO K745N 0.0016772 0 [A[G>C]G] Strong resistance 0.292 0.327 0.287 0.094 0.144 0.518112063459 0.76 NO R803L 0.0006593 -2 [C[G>T]G] Resistance 0.459 0.169 0.21 0.162 0.144 0.517807610559 -0.26 NO Q787E 0.0037355 2 [G[C>G]A] Resistance 0.317 0.303 0.274 0.106 0.143 0.516822352278 -0.63 NO K745T 0.0018677 -1 [A[A>C]G] Strong resistance 0.24 0.371 0.282 0.107 0.143 0.516114555189 0.76 NO I759M 0.0055991 1 [T[C>G]C] Resistance 0.461 0.168 0.225 0.145 0.143 0.515746876189 0.0 NO K728T 0.0018677 -1 [A[A>C]G] Resistance 0.328 0.293 0.277 0.103 0.142 0.514766486181 -0.34 NO V845L 0.00249 1 [G[G>T]T] Strong resistance 0.24 0.372 0.289 0.099 0.142 0.514492495474 -0.18 NO V845L 0.0035541 1 [G[G>C]T] Strong resistance 0.24 0.372 0.289 0.099 0.142 0.514492495474 -0.18 NO A840S 0.0024742 1 [A[G>T]C] Strong resistance 0.221 0.382 0.242 0.155 0.141 0.511709287321 1.08 NO D800E 0.0109232 2 [A[C>A]T] Resistance 0.482 0.14 0.154 0.225 0.141 0.511581080182 0.04 NO D800E 0.0047668 2 [A[C>G]T] Resistance 0.482 0.14 0.154 0.225 0.141 0.511581080182 0.04 NO A840T 0.0066366 0 [A[G>A]C] Strong resistance 0.281 0.324 0.208 0.187 0.14 0.511159774013 1.08 NO G779C 0.0006915 -3 [G[G>T]G] Resistance 0.321 0.296 0.266 0.118 0.14 0.510461877483 -0.18 NO Y801H 0.0053453 2 [C[T>C]A] Strong resistance 0.292 0.319 0.259 0.129 0.14 0.509823705808 -0.39 NO R803W 0.0113382 -3 [C[C>T]G] Resistance 0.382 0.236 0.233 0.149 0.139 0.507642565177 -0.26 NO I853F 0.0028478 0 [G[A>T]T] Strong resistance 0.277 0.332 0.259 0.132 0.139 0.507623165877 0.76 NO A763V 0.0094995 0 [G[C>T]C] Strong resistance 0.226 0.381 0.288 0.106 0.138 0.506729154249 -0.68 NO A743D 0.0115672 -2 [G[C>A]T] Strong resistance 0.256 0.356 0.304 0.084 0.138 0.50645496139 0.57 NO I744F 0.0040775 0 [T[A>T]T] Strong resistance 0.249 0.36 0.292 0.099 0.138 0.506436930811 0.36 NO K728N 0.0005698 0 [A[G>T]G] Resistance 0.375 0.248 0.292 0.085 0.138 0.505561627575 -0.34 NO K728N 0.0016772 0 [A[G>C]G] Resistance 0.375 0.248 0.292 0.085 0.138 0.505561627575 -0.34 NO I744T 0.0041101 -1 [A[T>C]C] Strong resistance 0.235 0.372 0.286 0.107 0.138 0.505379795248 0.36 NO T790P 0.0013146 -1 [C[A>C]C] Strong resistance 0.229 0.376 0.279 0.115 0.138 0.505316666916 0.04 NO V717G 0.0021293 -3 [G[T>G]G] Resistance 0.382 0.24 0.28 0.098 0.137 0.504711108098 -0.31 NO V843G 0.0003896 -3 [G[T>G]A] Strong resistance 0.276 0.335 0.288 0.102 0.136 0.502299417391 0.55 NO V843E 0.0039837 -2 [G[T>A]A] Strong resistance 0.274 0.336 0.288 0.103 0.136 0.501904401801 0.55 NO F795C 0.0013599 -2 [T[T>G]C] Strong resistance 0.299 0.312 0.28 0.109 0.135 0.500464796617 -0.66 NO K846Q 0.0003896 1 [G[A>C]A] Strong resistance 0.295 0.306 0.214 0.185 0.135 0.498892818821 -0.55 NO L844V 0.0047668 1 [A[C>G]T] Strong resistance 0.236 0.37 0.307 0.087 0.134 0.497525134299 1.51 NO I853T 0.0041101 -1 [A[T>C]C] Strong resistance 0.269 0.336 0.273 0.122 0.134 0.496878144985 0.76 NO I780F 0.0064421 0 [C[A>T]T] Strong resistance 0.274 0.331 0.27 0.125 0.134 0.49678501461 -0.28 NO D800Y 0.003034 -3 [G[G>T]A] Resistance 0.428 0.187 0.209 0.175 0.134 0.496716743782 0.04 NO K846E 0.0061893 1 [G[A>G]A] Resistance 0.313 0.293 0.248 0.146 0.133 0.494366766531 -0.55 NO K852R 0.009702 2 [A[A>G]G] Resistance 0.345 0.267 0.269 0.118 0.133 0.494172463865 0.01 NO I853L 0.0008582 2 [G[A>C]T] Strong resistance 0.259 0.344 0.279 0.118 0.132 0.492707562584 0.76 NO K846I 0.0038209 -3 [A[A>T]A] Strong resistance 0.25 0.35 0.262 0.139 0.132 0.492704492632 -0.55 NO G729R 0.0075322 -2 [G[G>A]G] Resistance 0.354 0.257 0.26 0.129 0.132 0.492044817881 -0.5 NO G729R 0.0024354 -2 [G[G>C]G] Resistance 0.354 0.257 0.26 0.129 0.132 0.492044817881 -0.5 NO K745M 0.0063126 -1 [A[A>T]G] Strong resistance 0.259 0.345 0.288 0.108 0.131 0.491651398408 0.76 NO K745E 0.0052871 1 [C[A>G]A] Strong resistance 0.298 0.308 0.279 0.114 0.131 0.491198975627 0.76 NO A767P 0.0044927 -1 [G[G>C]C] Resistance 0.318 0.281 0.205 0.195 0.131 0.490363971077 -0.68 NO L792R 0.0013611 -2 [C[T>G]C] Strong resistance 0.265 0.337 0.28 0.118 0.13 0.488736205178 -0.47 NO G857V 0.0006915 -3 [G[G>T]G] Strong resistance 0.227 0.368 0.265 0.141 0.129 0.486096833269 2.84 NO V717A 0.0048239 0 [G[T>C]G] Resistance 0.352 0.261 0.3 0.087 0.129 0.485907978862 -0.31 NO G729A 0.0037355 0 [G[G>C]A] Resistance 0.347 0.263 0.282 0.109 0.128 0.483580585695 -0.5 NO K716E 0.0052871 1 [C[A>G]A] Resistance 0.451 0.165 0.251 0.133 0.127 0.481490926953 -0.34 NO A767S 0.0023037 1 [G[G>T]C] Strong resistance 0.262 0.334 0.256 0.149 0.126 0.480774009067 -0.68 NO K745Q 0.0004936 1 [C[A>C]A] Strong resistance 0.265 0.329 0.254 0.152 0.125 0.477253047074 0.76 NO K728E 0.0051091 1 [T[A>G]A] Resistance 0.4 0.211 0.276 0.112 0.124 0.475757423259 -0.34 NO D761N 0.0167278 1 [C[G>A]A] Resistance 0.43 0.179 0.234 0.157 0.123 0.473965516303 -0.63 NO V786L 0.0028153 1 [C[G>T]T] Resistance 0.317 0.286 0.293 0.105 0.123 0.473207900264 -0.47 NO V786L 0.0055318 1 [C[G>C]T] Resistance 0.317 0.286 0.293 0.105 0.123 0.473207900264 -0.47 NO K716N 0.0018677 0 [A[A>C]G] Resistance 0.426 0.189 0.296 0.088 0.123 0.473144420095 -0.34 NO K716N 0.0063126 0 [A[A>T]G] Resistance 0.426 0.189 0.296 0.088 0.123 0.473144420095 -0.34 NO N842D 0.0061893 1 [G[A>G]A] Strong resistance 0.211 0.38 0.298 0.111 0.122 0.471133518419 2.49 NO A743T 0.010459 0 [C[G>A]C] Strong resistance 0.247 0.348 0.312 0.092 0.121 0.469995397757 0.57 NO F856V 0.0036054 -1 [T[T>G]T] Resistance 0.304 0.295 0.285 0.117 0.121 0.469862060721 2.89 NO A767V 0.0094995 0 [G[C>T]C] Strong resistance 0.271 0.322 0.268 0.139 0.121 0.469839507076 -0.68 NO G857A 0.0024354 0 [G[G>C]G] Resistance 0.341 0.259 0.26 0.141 0.121 0.468604598486 2.84 NO N842K 0.0016772 0 [A[C>G]G] Strong resistance 0.245 0.346 0.282 0.127 0.121 0.468484731508 2.49 NO N842K 0.0070042 0 [A[C>A]G] Strong resistance 0.245 0.346 0.282 0.127 0.121 0.468484731508 2.49 NO A763T 0.0066366 0 [A[G>A]C] Strong resistance 0.292 0.302 0.272 0.134 0.12 0.466355719361 -0.68 NO V786E 0.0062976 -2 [G[T>A]G] Resistance 0.333 0.269 0.296 0.103 0.119 0.465632228925 -0.47 NO I780L 0.003103 2 [C[A>C]T] Strong resistance 0.237 0.353 0.29 0.121 0.119 0.464319584148 -0.28 NO V843L 0.0028153 1 [C[G>T]T] Strong resistance 0.265 0.329 0.304 0.102 0.119 0.464208769639 0.55 YES V843L 0.0055318 1 [C[G>C]T] Strong resistance 0.265 0.329 0.304 0.102 0.119 0.464208769639 0.55 YES A763S 0.0024742 1 [A[G>T]C] Strong resistance 0.238 0.353 0.306 0.104 0.118 0.462835976677 -0.68 NO I780N 0.0031824 -3 [A[T>A]C] Strong resistance 0.27 0.32 0.275 0.135 0.118 0.462131600426 -0.28 NO A763D 0.0163385 -2 [G[C>A]C] Resistance 0.305 0.29 0.28 0.125 0.118 0.462093327506 -0.68 NO D800G 0.0029959 -1 [G[A>G]C] Resistance 0.37 0.228 0.251 0.151 0.117 0.460446498511 0.04 NO E746Q 0.0037355 2 [G[G>C]A] Resistance 0.458 0.151 0.265 0.125 0.116 0.459085760837 -0.42 NO P794S 0.0094995 -1 [G[C>T]C] Strong resistance 0.264 0.329 0.312 0.096 0.116 0.457855029415 -0.47 NO A840G 0.004516 0 [G[C>G]C] Resistance 0.312 0.278 0.256 0.154 0.115 0.456200299619 1.08 NO A743V 0.0095735 0 [G[C>T]T] Strong resistance 0.189 0.395 0.337 0.079 0.113 0.451187377188 0.57 NO L798R 0.0013611 -2 [C[T>G]C] Strong resistance 0.267 0.314 0.243 0.176 0.113 0.450996998177 -0.55 NO A767T 0.0082777 0 [G[G>A]C] Resistance 0.34 0.249 0.24 0.171 0.112 0.450612215277 -0.68 NO I780T 0.0041101 -1 [A[T>C]C] Strong resistance 0.277 0.31 0.29 0.123 0.112 0.449840475529 -0.28 NO N842S 0.0041043 1 [A[A>G]C] Strong resistance 0.199 0.381 0.301 0.119 0.112 0.449771115764 2.49 NO V717E 0.0062976 -2 [G[T>A]G] Resistance 0.348 0.248 0.3 0.104 0.112 0.449383856989 -0.31 NO H835L 0.0054667 -3 [C[A>T]C] sensitivity 0.277 0.315 0.329 0.079 0.111 0.448595983649 2.95 NO K728M 0.0063126 -1 [A[A>T]G] Resistance 0.329 0.266 0.305 0.1 0.111 0.448583376145 -0.34 NO I744L 0.003524 2 [T[A>C]T] Strong resistance 0.214 0.368 0.314 0.104 0.111 0.44671661141 0.36 NO A743G 0.0035541 0 [G[C>G]T] Resistance 0.319 0.273 0.301 0.107 0.11 0.445891869807 0.57 NO E758V 0.0039837 -2 [G[A>T]A] Resistance 0.423 0.172 0.242 0.164 0.108 0.441689854025 0.0 NO T854S 0.0054667 1 [C[A>T]C] sensitivity 0.26 0.329 0.344 0.067 0.108 0.441414836792 1.35 NO R803Q 0.0101281 1 [C[G>A]G] Resistance 0.372 0.216 0.241 0.171 0.108 0.441139921598 -0.26 NO A743P 0.0052067 -1 [C[G>C]C] Strong resistance 0.245 0.339 0.325 0.091 0.108 0.440728289324 0.57 NO L799P 0.0080975 -3 [C[T>C]G] Strong resistance 0.227 0.349 0.291 0.133 0.106 0.436096795609 0.01 NO K716T 0.0008383 -1 [A[A>C]A] Resistance 0.357 0.236 0.307 0.1 0.105 0.43559812465 -0.34 NO E746G 0.0061893 -2 [G[A>G]A] Resistance 0.381 0.205 0.23 0.184 0.105 0.435471717028 -0.42 NO K728Q 0.0012293 1 [T[A>C]A] Resistance 0.355 0.232 0.265 0.148 0.105 0.43529139024 -0.34 NO I759V 0.0080454 3 [A[A>G]T] Resistance 0.327 0.257 0.27 0.146 0.104 0.433609399998 0.0 NO Y801N 0.0038423 -2 [C[T>A]A] Resistance 0.315 0.267 0.277 0.14 0.104 0.432756385335 -0.39 NO I789N 0.0031824 -3 [A[T>A]C] Strong resistance 0.227 0.346 0.287 0.14 0.103 0.431140151268 -0.23 NO F856L 0.0045923 0 [T[T>A]G] Resistance 0.283 0.282 0.165 0.271 0.103 0.43038282516 2.89 NO F856L 0.002587 0 [T[T>G]G] Resistance 0.283 0.282 0.165 0.271 0.103 0.43038282516 2.89 NO F856L 0.0051562 0 [T[T>C]T] Resistance 0.283 0.282 0.165 0.271 0.103 0.43038282516 2.89 NO K852N 0.0038952 0 [A[G>T]A] Resistance 0.332 0.254 0.3 0.114 0.103 0.429578898939 0.01 NO K852N 0.0061444 0 [A[G>C]A] Resistance 0.332 0.254 0.3 0.114 0.103 0.429578898939 0.01 NO V742F 0.0028153 -1 [C[G>T]T] sensitivity 0.269 0.313 0.322 0.096 0.102 0.429275859872 -0.12 NO I853V 0.0048614 3 [G[A>G]T] Strong resistance 0.246 0.329 0.287 0.139 0.102 0.428264303148 0.76 NO V717L 0.0023559 1 [A[G>T]T] Resistance 0.336 0.251 0.317 0.096 0.102 0.427371140048 -0.31 NO V717L 0.004761 1 [A[G>C]T] Resistance 0.336 0.251 0.317 0.096 0.102 0.427371140048 -0.31 NO E758Q 0.0037355 2 [G[G>C]A] Resistance 0.496 0.1 0.241 0.163 0.1 0.424774310517 0.0 NO D761Y 0.0025561 -3 [C[G>T]A] Resistance 0.461 0.127 0.217 0.195 0.099 0.422688269731 -0.63 NO D800H 0.0037355 -1 [G[G>C]A] Resistance 0.404 0.174 0.192 0.23 0.099 0.422484203278 0.04 NO I789T 0.0041101 -1 [A[T>C]C] Strong resistance 0.221 0.348 0.286 0.145 0.099 0.421274596977 -0.23 NO Y801D 0.0004936 -3 [C[T>G]A] Resistance 0.321 0.258 0.28 0.142 0.099 0.421241587386 -0.39 NO L844M 0.0109232 2 [A[C>A]T] Resistance 0.29 0.282 0.258 0.169 0.098 0.420005060645 1.51 NO Q791R 0.0080393 1 [C[A>G]G] Strong resistance 0.225 0.347 0.318 0.11 0.098 0.419802647355 0.52 NO I789F 0.0064421 0 [C[A>T]T] Strong resistance 0.234 0.335 0.299 0.131 0.097 0.416782217464 -0.23 NO L777Q 0.0145206 -2 [C[T>A]G] Resistance 0.294 0.274 0.234 0.199 0.096 0.4157655853 -0.15 NO L844Q 0.0145206 -2 [C[T>A]G] Strong resistance 0.277 0.293 0.276 0.154 0.096 0.414695078336 1.51 NO Y801F 0.0040775 3 [T[A>T]T] Resistance 0.344 0.228 0.233 0.194 0.095 0.413617917232 -0.39 NO Q791L 0.0144798 -2 [C[A>T]G] Strong resistance 0.183 0.379 0.306 0.132 0.094 0.411972161037 0.52 NO Y764H 0.0053453 2 [C[T>C]A] Resistance 0.354 0.217 0.216 0.213 0.094 0.411728797528 0.0 NO P794H 0.0230425 -2 [C[C>A]C] Resistance 0.317 0.261 0.311 0.111 0.094 0.411408621831 -0.47 NO A767D 0.0163385 -2 [G[C>A]C] Resistance 0.334 0.238 0.257 0.17 0.094 0.410242492805 -0.68 NO R776G 0.0028566 -2 [C[C>G]G] Resistance 0.298 0.274 0.291 0.137 0.093 0.40846838762 -0.1 NO Y764C 0.0040182 -2 [T[A>G]C] Resistance 0.36 0.211 0.231 0.198 0.092 0.407136262288 0.0 NO G857R 0.0159371 -2 [T[G>A]G] Resistance 0.376 0.201 0.276 0.146 0.091 0.405215966832 2.84 NO G857R 0.0017754 -2 [T[G>C]G] Resistance 0.376 0.201 0.276 0.146 0.091 0.405215966832 2.84 NO E762D 0.0063126 2 [A[A>T]G] Resistance 0.344 0.232 0.296 0.128 0.09 0.403535682267 -0.63 NO E762D 0.0018677 2 [A[A>C]G] Resistance 0.344 0.232 0.296 0.128 0.09 0.403535682267 -0.63 NO K716Q 0.0004936 1 [C[A>C]A] Resistance 0.38 0.196 0.266 0.159 0.09 0.402559807231 -0.34 NO T790A 0.0039845 0 [C[A>G]C] Resistance 0.285 0.28 0.275 0.16 0.089 0.401326189678 0.04 NO A763G 0.004516 0 [G[C>G]C] Resistance 0.339 0.237 0.313 0.111 0.089 0.401015720454 -0.68 NO Y764F 0.0032174 3 [T[A>T]C] Resistance 0.428 0.143 0.212 0.217 0.087 0.39608817584 0.0 NO E762K 0.1023125 1 [T[G>A]A] Resistance 0.329 0.241 0.291 0.14 0.087 0.395023170437 -0.63 NO L788F 0.0095735 0 [G[C>T]T] sensitivity 0.264 0.3 0.307 0.128 0.086 0.394917643372 0.76 NO M766K 0.0063649 -1 [A[T>A]G] sensitivity 0.276 0.287 0.294 0.142 0.086 0.394574991171 -0.6 NO L777M 0.0180802 2 [C[C>A]T] Resistance 0.298 0.257 0.206 0.24 0.086 0.393343313001 -0.15 NO P794T 0.0163385 -1 [G[C>A]C] sensitivity 0.305 0.264 0.318 0.114 0.085 0.391575329269 -0.47 NO V765M 0.0143368 1 [C[G>A]T] Resistance 0.342 0.225 0.273 0.159 0.085 0.391260676704 -0.68 NO L788H 0.0055481 -3 [C[T>A]C] sensitivity 0.258 0.304 0.309 0.129 0.085 0.391215796337 0.76 NO G729E 0.0099217 -2 [G[G>A]A] sensitivity 0.298 0.267 0.299 0.136 0.084 0.390380884868 -0.5 NO I789L 0.003103 2 [C[A>C]T] Strong resistance 0.21 0.345 0.307 0.138 0.084 0.388982739307 -0.23 NO I759N 0.0031824 -3 [A[T>A]C] Resistance 0.324 0.241 0.282 0.153 0.084 0.388745852288 0.0 NO N842Y 0.0039837 -2 [G[A>T]A] sensitivity 0.254 0.308 0.318 0.121 0.083 0.387988458507 2.49 NO I759L 0.001088 2 [A[A>C]T] Resistance 0.334 0.233 0.292 0.141 0.083 0.387433432973 0.0 NO E758A 0.0003896 -1 [G[A>C]A] Resistance 0.345 0.213 0.215 0.227 0.082 0.385943878525 0.0 NO D800V 0.0028154 -3 [G[A>T]C] Resistance 0.389 0.184 0.294 0.133 0.082 0.385483905927 0.04 NO M766R 0.00192 -1 [A[T>G]G] sensitivity 0.28 0.28 0.294 0.146 0.082 0.385187758786 -0.6 NO K852E 0.0052871 1 [C[A>G]A] Resistance 0.305 0.257 0.292 0.146 0.081 0.383179433115 0.01 NO Q787H 0.0036835 0 [A[G>C]C] sensitivity 0.308 0.261 0.346 0.086 0.081 0.38229058892 -0.63 NO Q787H 0.0024742 0 [A[G>T]C] sensitivity 0.308 0.261 0.346 0.086 0.081 0.38229058892 -0.63 NO K852M 0.0063126 -1 [A[A>T]G] sensitivity 0.267 0.291 0.309 0.133 0.08 0.379962760967 0.01 NO I744V 0.0050166 3 [T[A>G]T] Strong resistance 0.194 0.356 0.313 0.137 0.079 0.378430732032 0.36 NO I759T 0.0041101 -1 [A[T>C]C] Resistance 0.315 0.244 0.289 0.152 0.078 0.375723566832 0.0 NO K852T 0.0018677 -1 [A[A>C]G] sensitivity 0.255 0.299 0.312 0.134 0.077 0.373531847149 0.01 NO D761E 0.0063649 2 [A[T>A]G] Resistance 0.483 0.082 0.19 0.245 0.076 0.372941798951 -0.63 NO D761E 0.00192 2 [A[T>G]G] Resistance 0.483 0.082 0.19 0.245 0.076 0.372941798951 -0.63 NO L778M 0.0115672 2 [G[C>A]T] Resistance 0.302 0.244 0.203 0.251 0.075 0.371114121763 -0.18 NO T790R 0.0016772 -1 [A[C>G]G] sensitivity 0.27 0.285 0.312 0.133 0.075 0.370572574142 0.04 NO F795S 0.004123 -2 [T[T>C]C] sensitivity 0.289 0.265 0.295 0.151 0.074 0.36795251064 -0.66 NO K852Q 0.0004936 1 [C[A>C]A] Resistance 0.295 0.255 0.261 0.19 0.073 0.366869819799 0.01 NO T790K 0.0070042 -1 [A[C>A]G] sensitivity 0.27 0.283 0.314 0.132 0.073 0.366720692189 0.04 NO R776P 0.0052067 -2 [C[G>C]C] Resistance 0.32 0.238 0.3 0.143 0.073 0.366697869618 -0.1 NO I759F 0.0038899 0 [A[A>T]T] Resistance 0.343 0.213 0.283 0.161 0.072 0.363922244211 0.0 NO G857E 0.0075322 -2 [G[G>A]G] Resistance 0.302 0.249 0.289 0.16 0.07 0.359534884822 2.84 NO L778Q 0.0145206 -2 [C[T>A]G] Resistance 0.298 0.244 0.232 0.226 0.069 0.356202483006 -0.18 NO V742I 0.0143368 3 [C[G>A]T] sensitivity 0.183 0.365 0.392 0.06 0.068 0.355711924266 -0.12 NO P794R 0.0052299 -2 [C[C>G]C] sensitivity 0.303 0.248 0.311 0.137 0.068 0.354602305368 -0.47 NO A767G 0.004516 0 [G[C>G]C] Resistance 0.387 0.172 0.291 0.15 0.068 0.354402992161 -0.68 NO D761G 0.0048614 -1 [G[A>G]T] Resistance 0.402 0.154 0.26 0.185 0.067 0.352473604364 -0.63 NO Q787K 0.0162718 1 [G[C>A]A] sensitivity 0.287 0.268 0.366 0.079 0.066 0.351440352459 -0.63 NO T790M 0.0116509 -1 [A[C>T]G] sensitivity 0.254 0.292 0.337 0.118 0.064 0.347136288125 0.04 NO Y727S 0.003524 -2 [T[A>C]T] sensitivity 0.249 0.3 0.367 0.084 0.064 0.346938626904 0.06 NO Y764N 0.0038423 -2 [C[T>A]A] Resistance 0.371 0.174 0.241 0.214 0.062 0.34151212193 0.0 NO L788I 0.0115672 2 [G[C>A]T] sensitivity 0.277 0.268 0.333 0.122 0.061 0.338971627102 0.76 NO N842I 0.0031358 -3 [A[A>T]C] sensitivity 0.213 0.324 0.338 0.125 0.06 0.337822460976 2.49 NO V742D 0.0028154 -3 [G[T>A]C] sensitivity 0.248 0.297 0.365 0.091 0.06 0.337710981919 -0.12 NO N842H 0.0003896 1 [G[A>C]A] sensitivity 0.223 0.314 0.329 0.134 0.06 0.337509642161 2.49 NO Q791P 0.003325 -1 [C[A>C]G] sensitivity 0.249 0.289 0.331 0.131 0.057 0.331813577851 0.52 NO I780V 0.0065275 3 [C[A>G]T] sensitivity 0.212 0.322 0.329 0.137 0.057 0.331678568396 -0.28 NO I744S 0.0006419 -2 [A[T>G]C] sensitivity 0.198 0.339 0.379 0.084 0.056 0.330094104191 0.36 NO Y764D 0.0004936 -3 [C[T>G]A] Resistance 0.374 0.165 0.239 0.223 0.055 0.327166028825 0.0 NO F795V 0.0031787 -1 [C[T>G]T] sensitivity 0.268 0.275 0.377 0.08 0.054 0.325949811618 -0.66 NO R803G 0.0028566 -2 [C[C>G]G] sensitivity 0.316 0.225 0.321 0.138 0.054 0.323810479063 -0.26 NO Q791E 0.0037355 2 [G[C>G]A] sensitivity 0.244 0.288 0.319 0.149 0.053 0.323483698278 0.52 NO V843I 0.0143368 3 [C[G>A]T] sensitivity 0.18 0.355 0.399 0.066 0.053 0.323223140577 0.55 NO F795L 0.0067893 0 [C[T>C]T] Resistance 0.268 0.258 0.248 0.226 0.053 0.32316137845 -0.66 NO F795L 0.0017928 0 [T[C>G]G] Resistance 0.268 0.258 0.248 0.226 0.053 0.32316137845 -0.66 NO F795L 0.0050087 0 [T[C>A]G] Resistance 0.268 0.258 0.248 0.226 0.053 0.32316137845 -0.66 NO L777V 0.0055493 1 [C[C>G]T] sensitivity 0.23 0.302 0.343 0.124 0.053 0.321683330489 -0.15 NO D761H 0.0054286 -1 [C[G>C]A] Resistance 0.422 0.112 0.18 0.286 0.052 0.319560160669 -0.63 NO I789V 0.0065275 3 [C[A>G]T] Strong resistance 0.174 0.346 0.298 0.182 0.051 0.319182539034 -0.23 NO P794L 0.0163176 -3 [C[C>T]C] sensitivity 0.259 0.278 0.354 0.11 0.051 0.318909405861 -0.47 NO E762A 0.0003896 -1 [G[A>C]A] sensitivity 0.231 0.296 0.316 0.156 0.051 0.317724470384 -0.63 NO F795Y 0.0033046 3 [T[T>A]C] sensitivity 0.299 0.241 0.375 0.085 0.048 0.312533371126 -0.66 NO K716I 0.0038209 -3 [A[A>T]A] sensitivity 0.324 0.218 0.365 0.094 0.048 0.312259815412 -0.34 NO L718R 0.0033774 -2 [C[T>G]G] sensitivity 0.258 0.264 0.317 0.161 0.042 0.298664741808 0.71 NO P741S 0.0436534 -1 [T[C>T]C] sensitivity 0.222 0.299 0.346 0.132 0.041 0.296422152141 -0.58 NO I853S 0.0006419 -2 [A[T>G]C] sensitivity 0.225 0.298 0.38 0.098 0.038 0.289376724955 0.76 NO G857W 0.0013404 -2 [T[G>T]G] Resistance 0.309 0.206 0.268 0.216 0.035 0.282871531379 2.84 NO L778V 0.0035541 1 [G[C>G]T] sensitivity 0.25 0.268 0.355 0.127 0.033 0.279626654902 -0.18 NO V765A 0.0048239 0 [G[T>C]G] sensitivity 0.274 0.234 0.277 0.216 0.029 0.271196857298 -0.68 NO V765G 0.0021293 -3 [G[T>G]G] sensitivity 0.264 0.243 0.304 0.19 0.026 0.264334082061 -0.68 NO L788R 0.0013611 -2 [C[T>G]C] sensitivity 0.21 0.291 0.31 0.19 0.025 0.261460014351 0.76 NO V765E 0.0062976 -2 [G[T>A]G] sensitivity 0.258 0.246 0.313 0.182 0.023 0.25823916003 -0.68 NO D761V 0.0028478 -3 [G[A>T]T] Resistance 0.413 0.11 0.333 0.144 0.021 0.253801917238 -0.63 NO L778R 0.0033774 -2 [C[T>G]G] sensitivity 0.218 0.274 0.286 0.222 0.018 0.247438950934 -0.18 NO R776H 0.010459 0 [C[G>A]C] sensitivity 0.293 0.208 0.296 0.204 0.017 0.244440885253 -0.1 NO P794A 0.004516 -1 [G[C>G]C] sensitivity 0.273 0.231 0.348 0.148 0.016 0.242819725622 -0.47 NO P741T 0.0236491 -1 [T[C>A]C] sensitivity 0.267 0.232 0.33 0.171 0.014 0.23770839054 -0.58 NO R803P 0.0028217 -2 [C[G>C]G] Resistance 0.338 0.168 0.33 0.164 0.013 0.236034851326 -0.26 NO T790S 0.0054667 1 [C[A>T]C] sensitivity 0.224 0.278 0.398 0.101 0.013 0.236015048879 0.04 NO Y801S 0.003524 -2 [T[A>C]T] sensitivity 0.28 0.224 0.37 0.126 0.012 0.235336602595 -0.39 NO P741H 0.0230425 -2 [C[C>A]C] sensitivity 0.274 0.227 0.351 0.148 0.012 0.235183594882 -0.58 NO L788V 0.0035541 1 [G[C>G]T] sensitivity 0.223 0.278 0.401 0.098 0.012 0.234982912076 0.76 NO E762V 0.0039837 -2 [G[A>T]A] sensitivity 0.273 0.228 0.354 0.146 0.011 0.233166660729 -0.63 NO I789S 0.0006419 -2 [A[T>G]C] sensitivity 0.17 0.322 0.388 0.12 0.011 0.231950957812 -0.23 NO L799Q 0.0145206 -2 [C[T>A]G] Resistance 0.322 0.175 0.291 0.212 0.01 0.230357335922 0.01 NO P741R 0.0052299 -2 [C[C>G]C] sensitivity 0.277 0.222 0.354 0.147 0.01 0.229960429928 -0.58 NO V765L 0.0028153 1 [C[G>T]T] sensitivity 0.255 0.238 0.332 0.176 0.009 0.227029805788 -0.68 NO V765L 0.0055318 1 [C[G>C]T] sensitivity 0.255 0.238 0.332 0.176 0.009 0.227029805788 -0.68 NO L799M 0.0180802 2 [C[C>A]T] Resistance 0.331 0.16 0.253 0.256 0.008 0.226148174943 0.01 NO L844R 0.0033774 -2 [C[T>G]G] sensitivity 0.227 0.261 0.354 0.158 0.004 0.217276980772 1.51 NO M766V 0.0048614 1 [G[A>G]T] sensitivity 0.225 0.267 0.395 0.113 0.003 0.214210391413 -0.6 NO I780S 0.0006419 -2 [A[T>G]C] sensitivity 0.214 0.275 0.411 0.099 -0.0 0.207934875734 -0.28 NO L777R 0.0033774 -2 [C[T>G]G] sensitivity 0.231 0.248 0.324 0.197 -0.002 0.204094266019 -0.15 NO M766I 0.0013404 1 [T[G>T]G] sensitivity 0.232 0.254 0.399 0.115 -0.004 0.19926799231 -0.6 NO M766I 0.0017754 1 [T[G>C]G] sensitivity 0.232 0.254 0.399 0.115 -0.004 0.19926799231 -0.6 NO M766I 0.0159371 1 [T[G>A]G] sensitivity 0.232 0.254 0.399 0.115 -0.004 0.19926799231 -0.6 NO L799V 0.0055493 1 [C[C>G]T] sensitivity 0.267 0.221 0.399 0.113 -0.007 0.194066133239 0.01 NO E762Q 0.0104917 2 [T[G>C]A] Resistance 0.338 0.144 0.332 0.185 -0.012 0.182221251701 -0.63 NO Q791H 0.0036835 0 [A[G>C]C] sensitivity 0.212 0.256 0.396 0.136 -0.021 0.163475723274 0.52 NO Q791H 0.0024742 0 [A[G>T]C] sensitivity 0.212 0.256 0.396 0.136 -0.021 0.163475723274 0.52 NO Y764S 0.0013017 -2 [T[A>C]C] Resistance 0.335 0.136 0.325 0.203 -0.023 0.15905113138 0.0 NO P741L 0.0163176 -3 [C[C>T]C] sensitivity 0.211 0.256 0.417 0.117 -0.025 0.155628460769 -0.58 NO Q791K 0.0162718 1 [G[C>A]A] sensitivity 0.204 0.253 0.423 0.119 -0.035 0.13292777146 0.52 NO L799R 0.0033774 -2 [C[T>G]G] sensitivity 0.286 0.167 0.333 0.215 -0.038 0.126298764316 0.01 NO M766T 0.0097428 -1 [A[T>C]G] sensitivity 0.208 0.237 0.377 0.178 -0.042 0.11753372157 -0.6 NO E758G 0.0061893 -2 [G[A>G]A] sensitivity 0.306 0.123 0.309 0.262 -0.063 0.0736443162673 0.0 NO I759S 0.0006419 -2 [A[T>G]C] sensitivity 0.234 0.193 0.455 0.118 -0.075 0.0472289512383 0.0 NO P741A 0.0055991 -1 [T[C>G]C] sensitivity 0.215 0.18 0.369 0.236 -0.095 0.002807157417 -0.58 NO E762G 0.0061893 -2 [G[A>G]A] sensitivity 0.207 0.185 0.363 0.245 -0.097 0.0 -0.63 NO K745* 0.0038423 -4 [C[A>G]A] NO K745* 0.0038423 -4 [C[A>G]A] NO E746* 0.003034 -4 [G[G>C]A] NO E746* 0.003034 -4 [G[G>C]A] NO E762* 0.0072735 -4 [T[G>C]A] NO E762* 0.0072735 -4 [T[G>C]A] NO Y764* 0.0070042 -4 [T[A>T]C] NO Y764* 0.0070042 -4 [T[A>T]C] NO Y764* 0.0016772 -4 [T[A>T]C] NO Y764* 0.0016772 -4 [T[A>T]C] NO Q791* 0.0099217 -4 [G[C>G]A] NO Q791* 0.0099217 -4 [G[C>G]A] NO K852* 0.0038423 -4 [C[A>G]A] NO K852* 0.0038423 -4 [C[A>G]A] NO C775* 0.0163385 -4 [T[G>T]C] NO C775* 0.0163385 -4 [T[G>T]C] NO K716* 0.0038423 -4 [C[A>G]A] NO K716* 0.0038423 -4 [C[A>G]A] NO E758* 0.003034 -4 [G[G>C]A] NO E758* 0.003034 -4 [G[G>C]A] NO K846* 0.0039837 -4 [G[A>G]A] NO K846* 0.0039837 -4 [G[A>G]A] NO Q787* 0.0099217 -4 [G[C>G]A] NO Q787* 0.0099217 -4 [G[C>G]A] NO Y727* 0.0038791 -4 [T[A>T]T] NO Y727* 0.0038791 -4 [T[A>T]T] NO Y727* 0.0008383 -4 [T[A>T]T] NO Y727* 0.0008383 -4 [T[A>T]T] NO Y801* 0.0063649 -4 [T[A>T]T] NO Y801* 0.0063649 -4 [T[A>T]T] NO Y801* 0.00192 -4 [T[A>T]T] NO Y801* 0.00192 -4 [T[A>T]T] NO K728* 0.0038584 -4 [T[A>G]A] NO K728* 0.0038584 -4 [T[A>G]A] NO G729* 0.0006915 -4 [G[G>C]G] NO G729* 0.0006915 -4 [G[G>C]G] NO