{"text_format":"2","workbook":"xlsx","n_sheets":2,"sheets":["A All pathways","B Most common pathways"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":0,"defined_names":0,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900"}

{"sheet":"A All pathways","index":0,"n_rows":32,"n_cols":107,"rows_kept":32,"cut":false,"hidden":false,"merged":[]}
[null,null,"05200 Pathways in cancer","00230 Purine metabolism","04020 Calcium signaling pathway","04510 Focal adhesion","04062 Chemokine signaling pathway","05206 MicroRNAs in cancer","05205 Proteoglycans in cancer","05203 Viral carcinogenesis","04010 MAPK signaling pathway","04060 Cytokine cytokine receptor interaction","04810 Regulation of actin cytoskeleton","04261 Adrenergic signaling in cardiomyocytes","04270 Vascular smooth muscle contraction","05210 Colorectal cancer","05410 Hypertrophic cardiomyopathy  HCM ","05414 Dilated cardiomyopathy","00240 Pyrimidine metabolism","04151 PI3K Akt signaling pathway","04912 GnRH signaling pathway","04260 Cardiac muscle contraction","04972 Pancreatic secretion","04726 Serotonergic synapse","05412 Arrhythmogenic right ventricular cardiomyopathy  ARVC ","04014 Ras signaling pathway","04015 Rap1 signaling pathway","04310 Wnt signaling pathway","04350 TGF beta signaling pathway","04512 ECM receptor interaction","04540 Gap junction","04660 T cell receptor signaling pathway","04666 Fc gamma R mediated phagocytosis","04915 Estrogen signaling pathway","04914 Progesterone mediated oocyte maturation","04916 Melanogenesis","04970 Salivary secretion","04724 Glutamatergic synapse","04725 Cholinergic synapse","04728 Dopaminergic synapse","04720 Long term potentiation","04730 Long term depression","04723 Retrograde endocannabinoid signaling","04722 Neurotrophin signaling pathway","04713 Circadian entrainment","05213 Endometrial cancer","05222 Small cell lung cancer","05223 Non small cell lung cancer","05010 Alzheimer s disease","05016 Huntington s disease","05034 Alcoholism","05130 Pathogenic Escherichia coli infection","05132 Salmonella infection","05152 Tuberculosis","05100 Bacterial invasion of epithelial cells","05166 HTLV I infection","00983 Drug metabolism   other enzymes","03430 Mismatch repair","03460 Fanconi anemia pathway","04012 ErbB signaling pathway","04330 Notch signaling pathway","04340 Hedgehog signaling pathway","04390 Hippo signaling pathway","04370 VEGF signaling pathway","04070 Phosphatidylinositol signaling system","04080 Neuroactive ligand receptor interaction","04514 Cell adhesion molecules  CAMs ","04144 Endocytosis","04110 Cell cycle","04114 Oocyte meiosis","04520 Adherens junction","04530 Tight junction","04650 Natural killer cell mediated cytotoxicity","04662 B cell receptor signaling pathway","04664 Fc epsilon RI signaling pathway","04670 Leukocyte transendothelial migration","04911 Insulin secretion","04910 Insulin signaling pathway","03320 PPAR signaling pathway","04917 Prolactin signaling pathway","04918 Thyroid hormone synthesis","04971 Gastric acid secretion","04973 Carbohydrate digestion and absorption","04727 GABAergic synapse","04360 Axon guidance","04380 Osteoclast differentiation","05202 Transcriptional misregulation in cancer","05212 Pancreatic cancer","05214 Glioma","05216 Thyroid cancer","05221 Acute myeloid leukemia","05220 Chronic myeloid leukemia","05217 Basal cell carcinoma","05218 Melanoma","05211 Renal cell carcinoma","05219 Bladder cancer","05215 Prostate cancer","05031 Amphetamine addiction","04930 Type II diabetes mellitus","05131 Shigellosis","05133 Pertussis","05164 Influenza A","05161 Hepatitis B","05160 Hepatitis C","05169 Epstein Barr virus infection","05146 Amoebiasis","05145 Toxoplasmosis"]
[null,"SUM",7,5,5,5,5,5,5,5,4,4,4,4,4,4,4,4,3,3,3,3,3,3,3,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1]
["RAF1",45,1,null,null,1,1,1,1,null,1,null,1,null,1,1,null,null,null,1,1,null,null,1,null,1,1,null,null,null,1,1,1,1,1,1,{"$nulls":4},1,1,null,1,null,1,null,1,null,null,1,null,null,1,{"$nulls":5},1,null,null,null,1,{"$nulls":8},1,1,1,null,null,1,null,1,{"$nulls":7},1,1,null,1,1,null,1,1,1,1,{"$nulls":4},1,1,1]
["RHOA",25,1,null,null,1,1,1,1,1,null,null,1,null,1,1,{"$nulls":6},1,null,null,1,1,1,1,null,null,1,{"$nulls":11},1,{"$nulls":7},1,null,1,1,{"$nulls":12},1,null,null,1,1,null,null,null,1,{"$nulls":8},1,{"$nulls":15},1]
["FLNB",4,null,null,null,1,null,null,1,null,1,{"$nulls":41},1]
["CCR3",3,{"$nulls":4},1,null,null,1,null,1]
["CCR8",3,{"$nulls":4},1,null,null,1,null,1]
["ITPR1",22,null,null,1,null,null,null,1,{"$nulls":5},1,{"$nulls":5},1,null,1,1,{"$nulls":6},1,null,null,1,null,null,1,1,1,1,1,1,1,null,1,null,null,null,1,1,{"$nulls":14},1,{"$nulls":4},1,{"$nulls":10},1,1]
["CACNA1D",21,null,null,1,{"$nulls":5},1,null,null,1,1,null,1,1,null,null,1,1,null,1,1,{"$nulls":12},1,1,1,null,null,1,null,1,null,null,null,1,{"$nulls":27},1,{"$nulls":5},1,1,{"$nulls":13},1,1]
["ITGA9",8,null,null,null,1,{"$nulls":6},1,null,null,null,1,1,null,1,{"$nulls":4},1,{"$nulls":4},1,{"$nulls":36},1]
["WNT7A",8,1,{"$nulls":5},1,{"$nulls":18},1,{"$nulls":7},1,{"$nulls":19},1,{"$nulls":5},1,1,{"$nulls":29},1]
["LAMB2",7,1,null,null,1,{"$nulls":13},1,{"$nulls":9},1,{"$nulls":16},1,{"$nulls":58},1,1]
["MLH1",5,1,{"$nulls":12},1,{"$nulls":29},1,{"$nulls":11},1,1]
["APPL1",2,1,{"$nulls":12},1]
["CCR2",2,{"$nulls":4},1,{"$nulls":4},1]
["ARPC4",6,{"$nulls":10},1,{"$nulls":19},1,{"$nulls":18},1,1,null,1,{"$nulls":44},1]
["CACNA2D3",6,{"$nulls":8},1,null,null,1,null,null,1,1,null,null,null,1,null,null,1]
["PPARG",6,1,{"$nulls":46},1,{"$nulls":28},1,{"$nulls":6},1,1,null,null,1]
["TNNC1",5,null,null,1,{"$nulls":8},1,null,null,1,1,null,null,null,1]
["ATP2B2",4,null,null,1,{"$nulls":8},1,{"$nulls":8},1,{"$nulls":13},1]
["CDC25A",3,{"$nulls":5},1,{"$nulls":26},1,{"$nulls":33},1]
["ENTPD3",3,null,1,{"$nulls":14},1,{"$nulls":85},1]
["FHIT",3,null,1,{"$nulls":42},1,1]
["KAT2B",3,{"$nulls":7},1,{"$nulls":45},1,{"$nulls":4},1]
["NME6",2,null,1,{"$nulls":14},1]
["HDAC11",2,{"$nulls":7},1,{"$nulls":40},1]
["IMPDH2",2,null,1,{"$nulls":52},1]
["HRH1",2,null,null,1,{"$nulls":60},1]
["ACVR2B",2,{"$nulls":9},1,{"$nulls":16},1]
["ENTPD5",2,null,1,{"$nulls":14},1]
["MIRLET7G",1,{"$nulls":5},1]
["MIR135A1",1,{"$nulls":5},1]

{"sheet":"B Most common pathways","index":1,"n_rows":32,"n_cols":16,"rows_kept":32,"cut":false,"hidden":false,"merged":[]}
["Names","05200 Pathways in cancer","00230 Purine metabolism","04062 Chemokine signaling pathway","04020 Calcium signaling pathway","04510 Focal adhesion","05203 Viral carcinogenesis","05205 Proteoglycans in cancer","05206 MicroRNAs in cancer","05210 Colorectal cancer","04810 Regulation of actin cytoskeleton","04060 Cytokine-cytokine receptor interaction","04010 MAPK signaling pathway"]
[null,{"$f":"SUM(B3:B32)","v":7},{"$f":"SUM(C3:C32)","v":5},{"$f":"SUM(D3:D32)","v":5},{"$f":"SUM(E3:E32)","v":5},{"$f":"SUM(F3:F32)","v":5},{"$f":"SUM(G3:G32)","v":5},{"$f":"SUM(H3:H32)","v":5},{"$f":"SUM(I3:I32)","v":5},{"$f":"SUM(J3:J32)","v":4},{"$f":"SUM(K3:K32)","v":4},{"$f":"SUM(L3:L32)","v":4},{"$f":"SUM(M3:M32)","v":4},null,"Driver","Suppressor"]
["RAF1",1,null,1,null,1,null,1,1,1,1,null,1,{"$f":"SUM(B3:M3)","v":8}]
["RHOA",1,null,1,null,1,1,1,1,1,1,null,null,{"$f":"SUM(B4:M4)","v":8},"X","X"]
["FLNB",{"$nulls":4},1,null,1,{"$nulls":4},1,{"$f":"SUM(B5:M5)","v":3}]
["CCR3",null,null,1,null,null,1,{"$nulls":4},1,null,{"$f":"SUM(B6:M6)","v":3}]
["CCR8",null,null,1,null,null,1,{"$nulls":4},1,null,{"$f":"SUM(B7:M7)","v":3}]
["ITPR1",null,null,null,1,null,null,1,{"$nulls":5},{"$f":"SUM(B8:M8)","v":2}]
["CACNA1D",null,null,null,1,{"$nulls":7},1,{"$f":"SUM(B9:M9)","v":2}]
["ITGA9",{"$nulls":4},1,{"$nulls":4},1,null,null,{"$f":"SUM(B10:M10)","v":2}]
["WNT7A",1,{"$nulls":5},1,{"$nulls":5},{"$f":"SUM(B11:M11)","v":2}]
["LAMB2",1,null,null,null,1,{"$nulls":7},{"$f":"SUM(B12:M12)","v":2}]
["MLH1",1,{"$nulls":7},1,null,null,null,{"$f":"SUM(B13:M13)","v":2},"X"]
["APPL1",1,{"$nulls":7},1,null,null,null,{"$f":"SUM(B14:M14)","v":2}]
["CCR2",null,null,1,{"$nulls":7},1,null,{"$f":"SUM(B15:M15)","v":2}]
["ARPC4",{"$nulls":9},1,null,null,{"$f":"SUM(B16:M16)","v":1}]
["CACNA2D3",{"$nulls":11},1,{"$f":"SUM(B17:M17)","v":1}]
["PPARG",1,{"$nulls":11},{"$f":"SUM(B18:M18)","v":1}]
["TNNC1",null,null,null,1,{"$nulls":8},{"$f":"SUM(B19:M19)","v":1}]
["ATP2B2",null,null,null,1,{"$nulls":8},{"$f":"SUM(B20:M20)","v":1}]
["CDC25A",{"$nulls":7},1,{"$nulls":4},{"$f":"SUM(B21:M21)","v":1}]
["ENTPD3",null,1,{"$nulls":10},{"$f":"SUM(B22:M22)","v":1}]
["FHIT",null,1,{"$nulls":10},{"$f":"SUM(B23:M23)","v":1},"X"]
["KAT2B",{"$nulls":5},1,{"$nulls":6},{"$f":"SUM(B24:M24)","v":1}]
["NME6",null,1,{"$nulls":10},{"$f":"SUM(B25:M25)","v":1}]
["HDAC11",{"$nulls":5},1,{"$nulls":6},{"$f":"SUM(B26:M26)","v":1}]
["IMPDH2",null,1,{"$nulls":10},{"$f":"SUM(B27:M27)","v":1}]
["HRH1",null,null,null,1,{"$nulls":8},{"$f":"SUM(B28:M28)","v":1}]
["ACVR2B",{"$nulls":10},1,null,{"$f":"SUM(B29:M29)","v":1}]
["ENTPD5",null,1,{"$nulls":10},{"$f":"SUM(B30:M30)","v":1}]
["MIRLET7G",{"$nulls":7},1,{"$nulls":4},{"$f":"SUM(B31:M31)","v":1}]
["MIR135A1",{"$nulls":7},1,{"$nulls":4},{"$f":"SUM(B32:M32)","v":1}]