TABLE S2. Activation Likelihood Estimation (ALE) Meta-Analyses Results for Social and Nonsocial Tasks Merged in Participants With Autism Spectrum Disorder (ASD) Versus Typically Developing Controls (TDC) Analysis,Side,Brain Region,BA,Talairach,Cluster Size (mm3),Extrema Value X,Y,Z ASD-child>TDC-child,R,Insula,13,34,16,8,768,0.02 ,L,Superior parietal lobule,7,−34,−64,48,464,0.02 ,L,Frontal lobe,6,−20,2,50,360,0.01 ,L,Pre-central gyrus,6,−32,−12,60,352,0.01 ,L,Insula,13,−36,14,4,288,0.01 ASD-adult>TDC-adult,R,Para-hippocampal gyrus/amygdala,,22,−4,−12,648,0.01 ,R,Medial frontal gyrus,8,8,44,40,632,0.02 ,L,Pre-central gyrus,6,−30,−14,62,328,0.01 ,R,Inferior occipital gyrus,19,38,−74,−8,272,0.01 ,L,Superior temporal gyrus,41,−56,−24,6,240,0.01 TDC-child>ASD-child,R,Superior temporal gyrus,22,50,−14,−4,792,0.01 ,R,Caudate,,12,2,12,504,0.02 ,R,Amygdala,,22,−10,−14,384,0.02 ,R,Frontal gyrus,,26,44,0,368,0.02 ,R,Fusiform gyrus,19,28,−66,−4,312,0.02 ,L,Amygdala,,−22,−8,−10,304,0.01 ,R,Putamen,,20,6,2,264,0.01 ,L,Precentral gyrus,44,−50,14,10,264,0.02 ,L,Inferior parietal lobule,40,−54,−52,38,248,0.01 ,R,Superior temporal gyrus,41,48,−32,8,224,0.01 TDC-adult>ASD-adult,L,Culmen,,−10,−46,0,368,0.01 ,L,Inferior frontal gyrus,13,−42,22,10,360,0.01 ,L,Anterior cingulate,32,−4,42,−2,296,0.01 ,L,Culmen,,−34,−54,−24,264,0.01 ,R,Claustrum,,34,12,2,256,0.01 ,L,Postcentral gyrus,3,−38,−22,46,200,0.01 Developmental Contrasts,,,,,,,, Greater in ASD-child vs. ASD-adult,R,Insula,13,38,20,14,760,2.64 ,L,Frontal lobe,6,−18,2,52,360,2.54 ,R,Middle frontal gyrus,46,44,30,20,184,2.85 ,L,Medial frontal gyrus,6,−3,−1,54,160,2.39 ,R,Precuneus,19,30,−66,36,104,2.20 ,R,Inferior frontal gyrus,9,32,10,28,56,2.30 ,R,Middle frontal gyrus,9,30,22,32,40,2.49 ,R,Middle frontal gyrus,8,30,28,36,40,1.92 Greater in ASD-adult vs. ASD-child,,NS,,,,,, Reduced in ASD-child vs. ASD-adult,R,Caudate,,12,3,12,504,2.38 ,R,Parahippocampal gyrus/amygdala,,−53,17,22,208,2.45 ,L,Inferior frontal gyrus,9,−52,22,20,184,2.26 ,R,Superior temporal gyrus,41,23,−7,−13,128,1.84 ,R,Putamen,,16,7,2,88,1.92 ,R,Superior temporal gyrus,22,52,−13,1,40,1.71 Reduced in ASD-adult vs. ASD-child,,NS,,,,,,