Supplementary Table 11 - Aligned genomic promoter sequences of miR-126 of mouse (mmu), human (hsa) and macaque (mml). mmu-mir126 GTCTGAGCAGCACATGGCCTCAGGACACAGCCAGAAGGGCAGGCTCT------GATGTGG 54 hsa-mir126 --GAGACCCTGAAATGTCCTGTATGCCCACACAA-GGGGCACACACCCCTAA-------- 49 mml-mir126 ----GGCCCTGAGAGGTCCCGTGTGCCCACACAA-GGGGCTCACACCCCCCAGTCTCAGC 55 * * * * * ** * ** ** **** * * mmu-mir126 GGAGTTCAGACTCCTCCCTGCCTATAGAGTACCCCAAAAAGGCCTAGGTGCATGAATTCT 114 hsa-mir126 --GTCTCAGAGTCCTCCTTCCTGGG-----------------------TGTGGGAGCTCC 84 mml-mir126 CTCGGGCAGAGTCCTCCTTCCTCGG-----------------------TGTGGGAGATCC 92 **** ****** * * ** ** ** mmu-mir126 CTCCCAGGCTCAAAATGCCAGATTTCAGAGGCTCCTGAGCCTCCAAAGTTCAGGAAATG- 173 hsa-mir126 ACC-------------CCCTGCTGGGGGAGGGGCCTGGGAATTCAGACTTCTGGAGGTTT 131 mml-mir126 ACC-------------CCCTGCTGGGGGAGGGGCTTGGGAATTCAGTCTCCTGGAGGTTT 139 * ** * * **** * ** * * ** * * *** * mmu-mir126 --------CTAGAGTCAAGAGAGC--AGCTTAAGCA--------CC-----AGGGGCCCA 210 hsa-mir126 AAGAAGGGCTCCGATGCCCAGGGCCCACACTCTGCCGTGACTCGCCGTAGGCCGGGCACA 191 mml-mir126 AAGAAGTGCTCCGATGCCCAGGGCCCACACTCTGCCATGACCCGCTGCAGG-----CAGG 194 ** * ** ** * * ** * * mmu-mir126 GA-----GTCCAGGCAAGGAAAGCAAGCCAGGCTCCGGCCAGCTCTGAAGTGGCCACTGC 265 hsa-mir126 CCCTCTCCTCTGGGCCTGGATGCCCCCACAGTAGGAGACCAGATAGGTGGGGGCACACAC 251 mml-mir126 CCCTCTCCTCTGGGCCTGGATGCCCCCACAGGAGGAGGCCAGATAGGTGGGGGCACACAC 254 ** *** *** * *** * **** * * * *** * mmu-mir126 AGGAAGGGG--CCGGCTCTGCTGTACTCTCTGG--------GTCTGTGTGTCATAGGCCA 315 hsa-mir126 AGGCCTGGCCACTGCCTCTGCTCCATGCGGAGTGTGGCTGGGCCTTCCTGCTGTGGCTTG 311 mml-mir126 AGGCCTGGCCACTGCCTCTGCTCCATGCAGAATGTGGCTGGGCCTTCCTGCTGTGGCTTG 314 *** ** * * ******* * * * ** ** * * mmu-mir126 AGTCATAGGAAACTTGGTGGATCAAGTGGCACACACAGGCTTGTATGCTGACCCACACGA 375 hsa-mir126 AGTCCCGGCCAGCA-CCGGAAGGCCCAGGCAGGGAAACGGCTGTGCAGTGACCCCTCAGT 370 mml-mir126 AGTCCCGGCCAGCA-CCGGAAGTCCCAGGCAGGGAAACGGCTGTGCAATGACCCCTCAGT 373 **** * * * * * **** * * * *** ****** * mmu-mir126 GCTGGGACTTGGGAAGGGAACCTCTGAGCCCAGGGAGTGATGCTGGTCAGGTAGCCACAA 435 hsa-mir126 GCCATCCCTTGAGGAGAAGACCCTTGGGGGCATGCTGGGGTGAC-----------CCTGT 419 mml-mir126 GCCATCCCTTGGGGAGAAGACCCCTGGGGACACGCTGGGGTGAC-----------TCTGT 422 ** **** * ** *** ** * ** * * * ** mmu-mir126 ACAAGTGATATGGGCATCCTTTCTGAGGAAGGTTTGACTAGGGTCACTCCATGTTGGGAC 495 hsa-mir126 GCACTCTGAGAGGGGACTCTAGATGCCCAGCAGGTGACTAAGGG---GGAGTAGGATGCC 476 mml-mir126 CCACTCTGAGAGGGGACTCTAGCTGCCCAGTGGGTGGCTAAGGG---GGAGTAGGATGCC 479 ** *** * ** ** * ** *** ** * * * mmu-mir126 CCCTCTGAACTACCCTTACTCACCACAGAACCATCTACCGGACTGCCTATCGCCGTAGCC 555 hsa-mir126 CCTCTGAGCTGTCCCACCCACCCCACAGAACCATCTATAGGACCGCCTACCGCCGCAGCC 536 mml-mir126 CCTCTGAGCTGTCCTGCCCACCCCACAGAACCATCTATAGGACCGCCTACCGCCGCAGCC 539 ** ** * * *************** **** ***** ***** **** mmu-mir126 CTGGGGTGACTCCCGCAAGGCCTCGCTATGCTTGCTGCCCTGGTTGGAAGAGGACCAGTG 615 hsa-mir126 CTGGGCTGGCCCCTGCCAGGCCTCGCTACGCGTGCTGCCCCGGCTGGAAGAGGACCAGCG 596 mml-mir126 CTGGGCTGGCCCCCGCCAGGCCTCGGTACGCATGCTGCCCCGGCTGGAAGAGGACCAGCG 599 ***** ** * ** ** ******** ** ** ******** ** ************** * mmu-mir126 GGCTCCCTGGGGCTTGTGGAGCAGGTGAGGGCAGTGTGCACTGTGCCTGATGTGAG---- 671 hsa-mir126 GGCTTCCTGGGGCCTGTGGAGCAGGTGAGGGCTATGTCCCTCGGCGCCCGGTGTTA---- 652 mml-mir126 GGCTTCCCGGGGCCTGTGGAGCAGGTGAGGGCTATGCCCCTCGGTGCCTGGTGTTAGTCA 659 **** ** ***** ****************** ** * * * mmu-mir126 ----GGACTCCACTGCCCA--------TCATTGCCCCTACTGCCTTTTATTCCT--CAAG 717 hsa-mir126 GGAGGGCGACTGTTCCCCAATCTTCCAGCAACGCTCCTGCTGCTTTTCTTGAACCCCGAG 712 mml-mir126 GAAGGGCAACTATTCCCCAGTCTTCCAGCAATGCTCCTGCTGCTTTTCTTGAACCCGGAG 719 ** * * **** ** ** *** **** *** * ** mmu-mir126 CAG------------------GGCAACCCTGCCCTGGCTGCTGCGGCGCTCTGGGGAGTC 759 hsa-mir126 CAAAGCACCACCTTGCCGCAGAGCACCCACTCCCTAGCAGCTGCCCCC-ACAGGGTGCTG 771 mml-mir126 CAAAGCACCACCTTGCCACAGAGCACCCACTCCCTAGCAGCTGCCCCC-ACAGGGCGCTG 778 ** *** ** **** ** ***** * * *** * mmu-mir126 TCTTGAGTCTGGATGCTCAGACAGGTCTCTTCTACCCACAGCAATATGCCAGCCTCCATG 819 hsa-mir126 GGGACCCAACTGAGCTGGTGACCAGCCTCCCCCGCCCACAGCAATATGCCAGCCGCCATG 831 mml-mir126 GGGACCCAACTGAGCTGGTGACCAGCCTCCCCTACCCACAGCAATATGCCAGCCGCCGTG 838 ** *** * *** * ******************** ** ** mmu-mir126 TGGGAATGGAGGGAGTTGCATCCGCCCAGGACACTGCCGCTGCCCTGTGGGATGGCAGGG 879 hsa-mir126 CCGGAACGGAGGGAGCTGTGTCCAGCCTGGCCGCTGCCGCTGCCCTGCAGGATGGCGGGG 891 mml-mir126 CCGGAACGGAGGAAGCTGCATCCAGCCTGGCCGCTGCCGCTGCCCTGCGGGATGGCAGGG 898 **** ***** ** ** *** ** ** * ************** ******* *** mmu-mir126 AGATACTTGCCAGACAGGTAAGCACCCTTCTTGAGGGGTCTTCTT-----GGTGCCTAGG 934 hsa-mir126 TGACACTTGCCAGTCAGGTGAGGCTGGCTCTACCCTGGGGGGCCCTGGAAGGGTCCTGGG 951 mml-mir126 TGACACCTGCCAGTCAGGTGAGGCTGGCTCCACCCTGGGGGACCCTGGAAGGGGCCTGGG 958 ** ** ****** ***** ** ** ** * ** *** ** mmu-mir126 TTACTGCTGG----------CTGAAGTGGGTTTTCACCGATAGATGGATCTTAATAGGGC 984 hsa-mir126 CACCTCCTTGCATGTCCTGGGGTTACTGCTGGCCCATGAGTGGGTGGTTGTGAAGGGAGC 1011 mml-mir126 CACCTCCTTGCATGTCCTGGGGTTACTGCTGGCCCATGAGTGAGTGATTGTGAAGGGAGC 1018 ** ** * * ** ** * ** * * ** * ** mmu-mir126 TCTGGGCCCAGGACCTCGCCTCCTGTAGACACTAGATTGACACCTTCATTTCTTACAGAT 1044 hsa-mir126 TGTGTGGGCAGGACCCCTCCCGC--AGGCATGGCCGCCTGACACCCCGTTTCCTGCAGAT 1069 mml-mir126 TATGTCGGCAGGACCCCTCCCAC--AGGCATGGCCGCCTGACACCCCATTTCCCACAGAT 1076 * ** ******* * ** * * * * **** ***** mmu-mir126 GTTGATGAATGCAGTACAGGAGAGGCCAGTTGTCCCCAGCGCTGTGTCAATACTGTGGGA 1104 hsa-mir126 GTGGATGAATGCAGTGCTAGGAGGGGCGGCTGTCCCCAGCGCTGCGTCAACACCGCCGGC 1129 mml-mir126 GTGGACGAATGCAGTGCTGGGGGGGCCGGCTGTCCCCAGCGCTGCGTCAACACCGCCGGC 1136 ** ** ********* * * ** * * ************** ***** ** * ** mmu-mir126 AGTTACTGGTGCCAGGGATGGGAGGGACAAAGCCCATCTGCAGATGGGACGCGCTGCCTG 1164 hsa-mir126 AGTTACTGGTGCCAGTGTTGGGAGGGGCACAGCCTGTCTGCAGACGGTACACTCTGTGTG 1189 mml-mir126 AGTTACTGGTGCCAGTGTTGGGAGGGGCACAGCCTGTCTGCAGATGGTACACACTGCGTG 1196 *************** * ******** ** **** ******** ** ** * *** ** mmu-mir126 TCTAAGGAGGGGCCCTCCCCGGTGGCCCCAAACCCCACAGCAGGTAAACTTGCCTTTCCC 1224 hsa-mir126 CCCAAGGGAGGGCCCCCCAGGGTGGCCCCCAACCCGACAGGTAAAC--AGCCCTGGCTGT 1247 mml-mir126 TCCAAGGGAGGGCCCCCCAGGGTGGCCCCCAACCTAACAGGTAAACTCAGCCCTGGCTGG 1256 * **** ****** ** ********* **** **** * mmu-mir126 ACCTGCTATGACTGACCTGGGTAGTCCTT-GGGTTGTGAGCACTGTTGTGTGGCTGAG-- 1281 hsa-mir126 GCCT---------GGCCTGGGGAGGCGGGCAGGCAGTGGACATTGCCGTGTGGC----TG 1294 mml-mir126 GCCT---------GGCCTGGGGAGGTGGGCAGCCTGTGGACATTGCCATGTGGCTCTGTG 1307 *** * ****** ** * *** ** ** ****** mmu-mir126 CTGAACATGGAAGAC-ACAGGGGCAGCTAGCCCT--GGGTGGAGGCCAGCACTATGCTGT 1338 hsa-mir126 TTAGGCATGGTGGGGGGCACTGGAATCTGGGCGGAAGGCGGTGGGGACTCCCTCTCCAGG 1354 mml-mir126 TTAGGCACGGTGAGGGGCACTGGAACCTGGGTGGAAGGTGGTGGGGGCTCCCTCTCCAGG 1367 * ** ** ** ** * ** * ** * ** * ** * * * mmu-mir126 GAGGGCTGGCTCCTTGCCTGGTGGAAGGGGCCACTTTACCCTGAAGAGGTTTCTGGAAGG 1398 hsa-mir126 GAGGGAG----GATGGGGAGGGAGGATAGGTG-GGTTCCCGAGAACTGGGGG-------- 1401 mml-mir126 GAGGGAA----GATGGGGCGGGAGGACAGGTG-GGTTCCTGAGAACTGGGGG-------- 1414 ***** * * ** * * ** ** * *** ** mmu-mir126 CATTGTGGGGCGTAAGGCATACCTGGGAGCCCCATCTCAGCCAGTTGAGTGAAAGAGCCC 1458 hsa-mir126 ---------------CAGGTTGCCCGGAGCCTCATATCAGCCAAGAAGGCAGAAGTGCCC 1446 mml-mir126 ---------------CAGGTTGCCTGGAGCCTCACGGTCAGCCAAGAAGGCGGAAGTGCC 1459 * * ****** ** * * * ** mmu-mir126 CACA-CTGGCTCTGGCAGCCTGGAGACGCCGCATCTTTGCCGG----------- 1500 hsa-mir126 CGTCCCGGGGTCCTGTCTGCATCCAGCGCAGCATTCTGGAAGACGCCACGCCTC 1500 mml-mir126 -------------CGTCTGCGTGCAGTGCAGCATTCTGGAAGACGCCACGCCCC 1500 * * ** **** * * *