Supplementary Table 14 - Aligned genomic promoter sequences of miR-133b of mouse (mmu), human (hsa) and macaque (mml). mmu-mir133b GCTACTTAACACCTCAATACCAAACATCATTATATGATATTTCTCAGTATCAAATTCTCA 60 hsa-mir-133b ---------------------------------GAGTTTCTTCTTCTTAGTCAGCTCTCT 27 mml-mir133b -------------------------------------GTCTTCTTCTTAGTCAGCTCTCT 23 **** ** * **** mmu-mir133b ATATCAAATAAATAATTAATAAATAGATAAA------------------TAATAAATAAA 102 hsa-mir-133b CCCACAGCTCACACCTCCCTAGAAACAGAGAGAAACCAGTGGGTACTCCTATTAGTTCAG 87 mml-mir133b CCCCCAGCTCACAGCTCCCTAGAAACAGAGAGAAACCAGTGGG-TCTCCTGTTAGTTCAG 82 ** * * * ** * * * * * * ** * * mmu-mir133b TAAATAAATAAATAAATAAATAAATAAAT-----AAAATCAAGAATGCATCAGTGGATTT 157 hsa-mir-133b TGGTTCTCAAACTTGAGCTGCATCGGAATCACCCAAAGGGCAGGTTATAGCACTAATTTC 147 mml-mir133b TGGTTCTCAAACTTGAGCTGCATCAGAATCACCCAAAGGGCAGGTTATAGCACTAATTTC 142 * * ** * * * *** *** ** * * ** * ** mmu-mir133b TGAACCCAGAAAATTTCAGGATGGTTTTGTTTGTTTTATTTTGTTTTGTTTTTAGAGACA 217 hsa-mir-133b TGGGTC----CTACTTCCAGATGTTTCGGGCTGGTAAGTGTTGCCATTCTTTTACAAGGC 203 mml-mir133b TGAGCC----CTACTTCCAGATGTTTTGGGCTAGTAAGTGTTGCCATTCTTTTATAAGGC 198 ** * * *** **** ** * * * * *** * ***** * mmu-mir133b GACTTTCTCTGTGTAGTGTTGGCTGTCCTGGAACTCACTCTGTAGAACAGGCTGGCCTCA 277 hsa-mir-133b CAACATACAAATCCAGAGTTCTC----C------------TTTAAAATCTGCAAGAAT-- 245 mml-mir133b CAACATACAAATCCAGAGTTCTC----C------------TTTAAAATCTGCAGGAAT-- 240 * * * ** *** * * * ** ** ** * * mmu-mir133b AACTCAAAGATCCATCTGCTTCTGCTTCCCAAGTGCTGGAATTTTAGGTGTGTGCCAC-- 335 hsa-mir-133b ----CAAAGATT--------TTTCCACCTCCTTTGAGAAACAGTTTAGTCAATGCTATCC 293 mml-mir133b ----CAAAGATT--------TCCCCACCTCCTTTGAGAAACAGTTTAGTCAATGCTACCC 288 ******* * * * * ** * ** ** *** * mmu-mir133b CACTGCCTGGCCATA---CTTTCTTCTCAATGACTTCTATTTATCAAGAAGAAGAAAACA 392 hsa-mir-133b CCTTGTTAAACCAAACAACCTCAATGTCTATGGCTGGGAGAATAAATAAATTATAGTA-T 352 mml-mir133b TCTTGTTAAACCAAACAACCTCAATGTCTATGGCTGGGAGAATAAATAAATTACAGTA-T 347 ** *** * * * * ** *** ** * * ** * * * mmu-mir133b TGTTAGCCAGTAACTAGCCCCAA-----AGGAGAAAGTTGGTTTTCTGCAAGCACTCAAC 447 hsa-mir-133b ATTCACACAGTAGAAAACCATAAAGCAATGAAAATTAATAAACTGCTGCTACCACATCAA 412 mml-mir133b ATCCACACAGTAGAAAACCATAAAGCAATGAAAATTAATAAACTGCTGCTACCACATCAA 407 * ***** * ** ** * * * * * **** * *** * mmu-mir133b TATCTTTTCGGCCTACATCTTTCCTCTCCTTATGCCAATACCTTATGGAGATAGCAAGCC 507 hsa-mir-133b TATGGATGAATCTTGCAAATATCATTTT-AAATGA-AATATCAAGTC-ACAAAACAATAC 469 mml-mir133b TATGGAGGAATCTTGCAAATATCATTTT-AAATGAAAATATCAAGTC-ACAAAACAATAC 465 *** * * ** * ** * * *** **** * * * * * *** * mmu-mir133b ATATTTTCGGGGAGCCTTTCCTTCTTACCTACACTTGATCTCACTTT------------- 554 hsa-mir-133b CTATGATATGATGCCATTATATACTAAAATATGCATATATATTGTTTAGAAATATATGCA 529 mml-mir133b CTATGATACAATGCCATTATACACTAAAATATGCATATATATTGTTTAGAAATATATGCA 525 *** * * ** ** * ** * * *** mmu-mir133b --ACTACTAACAAGCCGAAAGCAGAGGATACCCCTTCTATTCAATGGTTCTCAAACTTTA 612 hsa-mir-133b TAAATGGTAAAAACTATAAAGAAAAATATCAAAATCATAAGAAAAAAT-----AAATTCA 584 mml-mir133b TAAATGATAAAAAAAATAAAGAAAAATATTAAAATTATAAGAAAAAAT-----AAATTCA 580 * * *** ** **** * * ** * ** ** * ** ** * mmu-mir133b GATACCTCAGA--ATCACTGGGAAAGCAGGGTACATGAGTTTGGGGACCCCA-------- 662 hsa-mir-133b GTGTGATTGTTACCTCCGGGGGGAAACATAAAGAAATAAATTGGAAAAAGCATTCAGTAC 644 mml-mir133b GTGTGATTGCTACCTCTGGGGGGAAACATAAAGAAATACATTGGAAAAAGCATTCAGTAC 640 * * ** *** ** ** * * **** * ** mmu-mir133b ------CTCCTGGGTATGTCAGGGTGGTAAATGTTACTTTTCGCTTAAAAGGTCAACTTG 716 hsa-mir-133b AAAGAAAGCAATAGTATAAAACAGTAAAAAATAGTTCTTTTTA-----AAAGGTAGATCG 699 mml-mir133b AAAGAAAGCAGTAGTATAAAACAGTAAAAAATAGTTCTTTTTA-----AAAGGTAGATCG 695 * **** * ** **** * ***** ** * * * * mmu-mir133b TAAGTTCTTACATACTGGAATCCAGACTTCTTCATGATCTACAAGAACCAAAAATGCCTC 776 hsa-mir-133b TTGGGCCAGGC--------GTGATGGCTCACGGCTAAAATCCCAGCACTTTGAG------ 745 mml-mir133b TTGGACCAGGC--------ACGGTGGCTCAGGGCTGAAATCCTAGCACTTTGAG------ 741 * * * * * ** * * * * ** ** * mmu-mir133b TGTTTCCCTCGATAGACTCTACTAAAGTCAGTTCCACCCATTCTTTCAAACCAAAGGACT 836 hsa-mir-133b -----------------------AGGCTGAGATGGGTGGATCACCTGAGGTCAGGGGTTT 782 mml-mir133b -----------------------AGGCTGAGATGGGTGGATCACCTGAGATCAGGAGTTT 778 * * ** * ** * * ** * * mmu-mir133b GTGATAGCTATTACTGGGAGAAGGAATGAATATAATATATTTAAATAATAAAAAAACTGT 896 hsa-mir-133b GAGACCAGCCTGGCCAACATGG---CAAAACCCCATTTCTACTCAAAATACAAAAATAGC 839 mml-mir133b GAGACCAGCCTGGCCAACATAG---CAAAACCCCATTTCTACTAAAAATACAAAAATAGC 835 * ** * * * ** ** * * * **** ***** * mmu-mir133b CAAACAATGTAAATTAGTGAATTGTAGTTACCATATTCATATGAATGAGCCTTACAGATA 956 hsa-mir-133b -GGGACATGGTGGCAGGTGTCTGTAATTCCAGCTACTCAGGAGTTTGAGGCAGGAGAATC 898 mml-mir133b -CGGGCATGGTGGCAGGTGTCTGTAATTTCAGCTACTCAGGAGGCTGAGGCAGGAGAATC 894 *** *** * * * ** *** * **** * ** mmu-mir133b TCATGTAAGGTAAAATTAAAATGCCACAGATAAATATTTATAATATTAAAATATATTGAT 1016 hsa-mir-133b ACTTGAAACAGGAGGCAGAGGTTGCAG--------TGAGCTGAGATAGCGCC--ACTGCA 948 mml-mir133b ACTTGAAACAGGAGGCAGAGGTTGCAG--------TAAGCTGAGATCACGCC--ACTGCA 944 * ** ** * * * ** * * ** * ** mmu-mir133b TCAGAACATGCATAAATGAGAAAAGCTATAAAGAAAAACATCTAAATTACAAGAAAACAA 1076 hsa-mir-133b CTCCAGCCTGGGTGACAGAGTGAGACTCCAT----------CTCAAAAAAGTAACAACAA 998 mml-mir133b CTCCAGCCTGGGTGACAAAGCAAGACTCCAT----------CTCAAAAAA-TAACAACAA 993 * * ** * * ** * ** * ** ** * * ***** mmu-mir133b GAAACTCAGTATCATAGTTACTGTATATTCC--------------CCACCCACTTAT--- 1119 hsa-mir-133b AAAAAAGTAGATCGTTGTTCATGGGTATTGGTTTTACCATTATGTACCATCACTTATATA 1058 mml-mir133b AAAAAAGTAGATCGTTGTTTATGGGTTTTGGTTTTACCACTATGTACCATCACTTACATA 1053 *** *** * *** ** * ** * ****** mmu-mir133b ----ATTTCATTTTTAATGCAAACATGATACATTCATA-------GAGGGTTATATAATG 1168 hsa-mir-133b TTATAAATATTCTTTTATAAATATATCATACTTGAATTAAAAACATAATTTAAAGAAATT 1118 mml-mir133b TTATAAATATTATTGTATAACTATATCATATTTGAATTAAAAATAAAATTTAAAGAAATT 1113 * * * ** ** * ** *** * ** * * * *** mmu-mir133b TACATTTACATATGCATACAAATATACTTGACAATGTTAAGGTTATTTTAGAATATAAAA 1228 hsa-mir-133b AAAATGTTAAGCATTCAAAGAATATATGCCAAAATGTTACATTTCTTTCGGAAAATGGGA 1178 mml-mir133b AAAATGTTAAGCATTCAGAGAATATATGCCAAAATGTTACATTTCTTTTGGAAAATGGGA 1173 * ** * * ****** * ******* ** *** *** ** * mmu-mir133b ----------GAAAAGAGTGTCTATTTTTTCCATATTCTATAACTGTATTCCATTTTCGT 1278 hsa-mir-133b AGAGGAAGCATTATGGCATACTGTCATTTTTCATATTCTATAATTCTATAGCATATTTGA 1238 mml-mir133b AGAGGACGCATTACAGCATACTGTCATTTTCCATATTCTATAATTCTATATCGTATTTGT 1233 * * * **** ************ * *** * * ** * mmu-mir133b GCC---TAATGTTCCAATTTGAAAAAAAAATAAGAGCTAAATAAAATAAATAAATAAAAA 1335 hsa-mir-133b TCTTCATGATGTTTCTATTTGAAAAAAGATTAAAGATTAAAGA-AAAAATAAATTGAAGT 1297 mml-mir133b TCTTCATGATGTTTCTATTTGAAAAAAGAATGAAGATTAAAGAAAAAAATAAATTGAAGT 1293 * * ***** * *********** * * * **** * ** ** ** * ** mmu-mir133b CTAAAA----AGCATAC-GACTTTGTGAGATTTCT------------------------- 1365 hsa-mir-133b CATGCAACATGAAATACAAATTATGTATGATTTGTATGTACAAATTGTATGAGATGTATG 1357 mml-mir133b CATGCAATGCGAAATATAAATTATGTATGATTTGTATGTACAAATCATATGAGATGTATG 1353 * * *** * * *** ***** * mmu-mir133b TTCAAGCTCTGTGAGAGGTTAGTCAGGATAATGTT--CTCTTTGGGGTTGATTCATGCTA 1423 hsa-mir-133b TACAAATCATGTAAGAGGACATTCTGGACAAGGCAAGCTCCTGGCATTTGACAGATGCTA 1417 mml-mir133b TACAAATCATGTGAGAGGACATTCTGGACAAGGCAAGCTCTTGGCATTTGATAGATGCTA 1413 * *** *** ***** * ** *** ** * *** * * **** ****** mmu-mir133b AT---GTGGTTCTCTCTGTTACAGGCTTGGACAAGTGGTGCTCAAACTCC---AAGGACT 1477 hsa-mir-133b ATGCTGCTTCTTTTTGCATTACAGGCTTAGACAAATGATGCTTGAGACACACCAAGATAC 1477 mml-mir133b ATGCTGCTTCTTTTTGCATTACAGGTTTAGACAACTGATGCTTGAGACACACCAAGGTAC 1473 ** * * * * ******* ** ***** ** **** * * *** mmu-mir133b TCACAAGCTTCAGGCTGCAGTCA---- 1500 hsa-mir-133b CTGCACACTAGAGGCTGCAGTCA---- 1500 mml-mir133b CTGCACACTAGAGGCTGCAGTCACCTC 1500 ** ** ************