Table 6. Genomic locations of SRC-3 binding clusters and their nearby estrogen response elements (EREs)
|
Binding site ID |
Cluster coordinates * |
ERE sequences † |
ERE coordinates * |
|
Strong binding sites |
|||
|
FSIP1 |
chr15:37748186-37748883 |
GAGGTCAGAGTGACCGT |
chr15:37748137-37748153 |
|
CD512930 |
chr13:38157118-38157185 |
AGGGTCACAATGCCTGG |
chr13:38157121-38157137 |
|
Clust2-36 |
chr2:240729410-240729479 |
caGGTCAcagtgacaat |
chr2:240729490-240729506 |
|
CAP2 |
chr6:17497827-17497870 |
CAGGTCAAACAGGCCCT |
chr6:17497641-17497657 |
|
Clust10-9 |
chr10:43989138-43989317 |
CAGCTCATTATGACTTC |
chr10:43988943-43988959 |
|
BU624419 |
chr8:122232486-122232569 |
TAGTTCACCCTGCCCTA |
chr8:122232522-122232538 |
|
FER1L3 |
chr10:95184626-95185161 |
AAAGTCAAAATGACCTG |
chr10:95184950-95184966 |
|
CACNA2D3 |
chr3:54363188-54363297 |
||
|
Clust6-7 |
chr6:53437817-53437891 |
gagcccagtgTGACCtg caggacactgtgacatt |
chr6:53437818-53437834 chr6:53437887-53437903 |
|
PARD6B-5' |
chr20:48777410-48777487 |
AGGGTCAAGGTCACCCA |
chr20:48777460-48777476 |
|
PARD6B-3' |
chr20:48811488-48811925 |
tgagtcactgtgcctgg |
chr20:48812630-48812646 |
|
FLJ20294 |
chr11:46572166-46572237 |
AGGGTCAAAGTGCGCAA |
chr11:46571645-46571661 |
|
IER3 |
chr6:30827455-30827497 |
CAGCTCAGCCTGACCCA |
chr6:30827505-30827521 |
|
DSCAM, AF401032 |
chr21:40673751-40673798 |
||
|
BG250131 |
chr20:51916180-51917271 |
||
|
TBXAS1 |
chr7:138924112-138924447 |
TAAATGAGGATGACCTG |
chr7:138924185-138924201 |
|
C1orf21 |
chr1:181174283-181174350 |
||
|
CBWD2 |
chr2:113910517-113910916 |
TAGGTCAGGCTACCCAC |
chr2:113911284-113911300 |
|
Weak binding sites |
|||
|
RGS8 |
chr1:179387508-179387726 |
aagcagacttTGACCtg |
chr1:179387412-179387428 |
|
C20orf4 |
chr20:34288626-34288816 |
GCGGTGAGTGTGGCCTC |
chr20:34287837-34287853 |
|
BU596660 |
chr5:18087670-18087715 |
||
|
AL709692 |
chr4:140177556-140177603 |
||
|
GALNT11, BC059377 |
chr7:151211242-151211286 |
||
|
BC038557 |
chr5:172653872-172653916 |
GATGTCAGTGTGGCCAT GTGGCCATTGAGACCTG |
chr5:172654839-172654855 chr5:172654848-172654864 |
|
AL833283 (DNMBP) |
chr10:101758527-101758571 |
||
|
DKFZp434L142 |
chr4:159452299-159452345 |
CAGGGGCTGATGACCTT AAGGAATAACTGACCTG |
chr4:159451900-159451916 chr4:159452448-159452464 |
|
NRAS |
chr1:114972488-114972535 |
CAGGACACAGTAACCAG CTGGTCCCCTTGGCTGA |
chr1:114971908-114971924 chr1:114973287-114973303 |
|
BANP |
chr16:86536140-86536180 |
TTGGTCACAGTAATTTC ttGGTCAggctggtctc CGGACCATGCCGACCAC tgggccaggcTGACCcc |
chr16:86535601-86535617 chr16:86535885-86535901 chr16:86536340-86536356 chr16:86536852-86536868 |
|
IGFBP2 |
chr2:217316957-217317007 |
ttGGTCAggctgctctt TTGGTCACTGTGGAGTC |
chr2:217316245-217316261 chr2:217316581-217316597 |
*Coordinates according to May 2004 human reference sequence (hg17).
†
Perfect ERE halfsites (GGTCA) are underlined.