Toll-Like Receptor 2 and Mincle Cooperatively Sense Corynebacterial Cell Wall Glycolipids

Supplemental material

• Supplemental file 1 -

  Fig. S1. Cell wall extracts of corynebacteria specifically bind to Mincle-Fc fusion protein but not to Clec9a-Fc used as a negative control. Fig. S2. G-CSF and NO production in macrophages stimulated with C. diphtheriae DSM43989 glycolipids is TLR2 dependent. Fig. S3. Mincle surface expression is abrogated in Mincle^−/− macrophages.

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