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["Supplementary table 1: selection of 273 drugs/compounds tested on the three myxoid liposarcoma cell lines."]
["Drug name","Target"]
["ABT-263(Navitoclax)","Bcl-2, Bcl-xl, Bcl-w"]
["Bosutinib(SKI-606)","Src, Abl"]
["Panobinostat","HDAC"]
["Trichostatin A","HDAC"]
["SB 431542","ALK"]
["Iniparib ","PARP"]
["LY294002","PI3K"]
["TW-37","Bcl-2, Bcl-xl"]
["ABT-737","Bcl-2, Bcl-xl, BH3-mimetic"]
["Cediranib (AZD2171)","VEGFR"]
["Motesanib Diphosphate","VEGFR"]
["Vandetanib","VEGFR"]
["Crizotinib (PF-02341066)","c-MET, ALK"]
["NVP-ADW742","IGF-1R"]
["PHA-739358 (Danusertib)","Aurora"]
["Mocetinostat","HDAC"]
["ABT-869 (Linifanib)","VEGFR"]
["CI-1033 (Canertinib)","EGFR, ErbB"]
["Nilotinib","Bcr-Abl"]
["Vorinostat (SAHA)","HDAC"]
["ZSTK474","PI3K"]
["KU-55933","ATM"]
["TAE684","ALK"]
["Abiraterone (CB-7598)","CYP17"]
["ABT-888","PARP"]
["CI-1040 (PD184352)","MEK"]
["Pazopanib HCl","VEGFR"]
["VX-680","Aurora"]
["SB 216763","GSK-3"]
["PF-04217903","MET"]
["BI 2536","PLK1"]
["YM155","Survivin suppressant"]
["Axitinib","VEGFR"]
["Dasatinib","Src, Abl"]
["PD0325901","MEK"]
["Entinostat","HDAC"]
["SB 203580","MAPK"]
["LAQ824","HDAC"]
["XL880 (GSK1363089)","VEGFR"]
["INO-1001","PARP"]
["AZD0530 (Saracatinib)","Src"]
["Deforolimus (MK-8669)","mTOR"]
["PI-103","PI3K, mTOR, DNA-PK"]
["Enzastaurin","PKCβ"]
["SB 202190","p38 MAPK"]
["JNJ-26481585","HDAC1"]
["SGX-523","MET"]
["MLN8237 (Alisertib) ","Aurora A"]
["AZD6244 (Selumetinib)","MEK1, ERK1/2"]
["Erlotinib HCl","EGFR"]
["Rapamycin (Sirolimus)","mTOR"]
["BMS-599626","HER1, HER2"]
["MK-2206 DiHCl","Akt1/2/3"]
["Rucaparib (AG-014699, PF-01367338)","PARP"]
["JNJ-38877605","c-MET"]
["AT9283","JAK2/3"]
["BEZ235","PI3K, mTOR"]
["Gefitinib (Iressa)","EGFR"]
["Sorafenib Tosylate","Raf-1, B-Raf,VEGFR-2"]
["Obatoclax Mesylate","Bcl-2"]
["PD153035 HCl","EGFR"]
["Vatalanib","VEGFR2/KDR"]
["PD0332991","CDK4/6"]
["Pemetrexed disodium","TS, DHFR, GARFT"]
["BIBF1120 (Vargatef)","VEGFR1/2/3, FGFR1/2/3, PDGFRα/β"]
["Imatinib Mesylate","v-Abl, c-Kit, PDGFR"]
["Sunitinib Malate","VEGFR2, PDGFRβ"]
["AZD2281 (Olaparib)","PARP1/2"]
["SU11274 (PKI-SU11274)","MET"]
["U0126-EtOH","MEK1, MEK2"]
["XL147","PI3K"]
["17-AAG","HSP90"]
["Afatinib","EGFR, HER2"]
["Lapatinib Ditosylate","EGFR, ErbB2"]
["Tandutinib (MLN518)","PDGFR, c-Kit"]
["Masitinib (AB1010)","Kit, PDGFRα/β"]
["Vismodegib","Hedgehog"]
["ZM-447439","Aurora A/B"]
["XL184","VEGFR2, c-Met, Ret, Kit, Flt-1/3/4, Tie2, AXL"]
["17-DMAG HCl","HSP90"]
["Bortezomib","20S"]
["Lenalidomide","TNFα"]
["Temsirolimus","mTOR"]
["GDC-0941","PI3Kα/δ"]
["Belinostat (PXD101)","HDAC"]
["GDC-0879","B-RAF, C-RAF"]
["Everolimus (RAD001)","mTOR"]
["AG-490","EGFR, JAK2, ErbB2"]
["VX-770","G551D-CFTR, F508del-CFTR"]
["Capecitabine (Xeloda)","Antimetabolites"]
["NPI-2358","VDA"]
["Aprepitant","neurokinin-1"]
["Dutasteride (Avodart)","5-alpha-reductase"]
["Cerubidine","Anthracyclines"]
["Fludarabine Phosphate","Antimetabolites"]
["JNJ-7706621","CDK1/2, Aurora A/B"]
["SNS-032 (BMS-387032)","CDK2/7/9"]
["ABT-751","β-tubulin"]
["PD98059","MEK-1"]
["Bicalutamide (Casodex)","AR antagonist"]
["PIK-75 HCl","p110α, DNA-PK"]
["Clofarabine","Antimetabolites"]
["Flavopiridol (Alvocidib)","CDK1, CDK2, CDK4 and CDK6"]
["Entecavir hydrate","antivirals"]
["Cyclopamine","Hedgehog"]
["Cisplatin","Alkylating, platinum drugs"]
["BAY 73-4506 (Regorafenib)","VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1"]
["Fulvestrant","Estrogen receptor"]
["Bisoprolol Fumarate","β1 adrenergic receptor"]
["OSI-930","Kit, KDR and CSF-1R"]
["Topotecan Hydrochloride","Topoisomerase I"]
["Barasertib","Aurora B"]
["CP-724714","HER2, ErbB2"]
["WZ8040","EGFR (T790M)"]
["Raltitrexed (Tomudex)","Antimetabolites"]
["AV-951 (Tivozanib)","VEGFR1/2/3 (PDGFR and c-Kit)"]
["Dacarbazine","Alkylating, Triazines"]
["2-Methoxyestradiol","Depolymerisation microtubules, HIF-1α"]
["Nepafenac","NSAID"]
["Docetaxel","Mitotic inhibitor, Taxanes"]
["XAV-939","Tankyrase 1/2 (Wnt/β-catenin)"]
["Thalidomide","E3 ubiquitin ligase"]
["Doxorubicin ","Anthracyclines"]
["Dexrazoxane HCl","Cardioprotective agent"]
["Letrozole","Aromatase"]
["Rufinamide","Triazole derivative (anticonvulsant)"]
["Gemcitabine","Antimetabolite"]
["TGX-221","p110β"]
["ENMD-2076","Aurora A, Flt3"]
["CUDC-101","HDAC class I/II, EGFR, HER2"]
["Adrucil (Fluorouracil)","Antimetabolite"]
["Epirubicin HCl","Anthracyclines"]
["Leucovorin Calcium","Reduced folic acid"]
["Posaconazole","C14ɑ demethylase"]
["Paclitaxel (Taxol)","Mitotic inhibitor, Taxanes"]
["WZ3146","EGFR(L858R), EGFR(E746_A750)"]
["Danoprevir (ITMN-191)","Hepatitis C virus"]
["Exemestane","Aromatase "]
["Imiquimod","Immune response modifier"]
["Eloxatin","Alkylating, platinum drug"]
["Methazolastone","Alkylating, triazines"]
["Prasugrel","Platelet inhibitor"]
["PLX-4720","B-RafV600E, c-Raf-1"]
["CYC116","Aurora A/B, VEGFR"]
["Ritonavir","HIV protease"]
["Finasteride","Type II 5α-reductase"]
["Bendamustine HCl","Alkylating, nitrogen mustards"]
["Etoposide (VP-16）","Topoisomerase II"]
["Vincristine Sulfate","Mitotic inhibitors, vinca alkaloids"]
["Ramelteon (TAK-375)","Melatonin receptor"]
["Roscovitine (CYC202)","Cdc2, CDK2, CDK5"]
["JNJ 26854165","p53, MDM2"]
["BIBR1532","Telomerase"]
["Irinotecan","Topoisomerase I "]
["Nelarabine","Antimetabolites"]
["KU-0063794","mTOR"]
["Agomelatine","5-HT2C receptor"]
["Cinacalcet HCl","CaSR (Ca receptor)"]
["SNS-314 Mesylate","Aurora"]
["WZ4002","EGFR(L858R), (T790M)"]
["PIK-90","PI3Kα/γ/δ"]
["Cladribine","Antimetabolites"]
["Bleomycin sulfate","Anti-tumor antibiotics"]
["Evista","Estrogen antagonist"]
["Amuvatinib ","c-Kit, PDGFRα and Flt3"]
["Celecoxib","COX-2 inhibitor"]
["S31-201","STAT3"]
["BIIB021","HSP90"]
["Geldanamycin","HSP90"]
["Ceftiofur HCl","Antibiotic"]
["Testosterone propionate","Testosterone hormone"]
["Trazodone HCl","Serotonin antagonist"]
["OSI-027","mTOR"]
["TAK-875","GPR40"]
["Ciprofibrate","Peroxisome proliferator-activated receptor agonist"]
["AS-604850","PI3Kγ"]
["CP91149","Glycogen phosphorylase"]
["Cefprozil hydrate","Antibiotic"]
["Cortisone acetate ","Glucocorticoid hormone"]
["Tioxolone","Metalloenzyme carbonic anhydrase I"]
["LY2603618 (IC-83)","Chk1"]
["NU7441","PI3K, DNA-PK"]
["PF-3845","FAAH"]
["WAY-600","mTOR"]
["TAK-901","Aurora A/B"]
["Tiotropium Bromide (Spiriva)","Muscarinic receptor"]
["Clomifene citrate (Serophene)","Estrogen receptor"]
["DHEA","Steroid hormone"]
["Tubastatin A HCl","HDAC6"]
["SNX-2112","HSP90"]
["S/GSK1349572","HIV virus"]
["ADX-47273","Glutamate receptor"]
["AMG900","Aurora"]
["Tiotropium Bromide hydrate","Muscarinic receptor"]
["Hydralazine HCl","Smooth muscle relaxant"]
["Fluocinonide ","Glucocorticoid"]
["PF-05212384","PI3K, mTOR"]
["PF-04929113 (SNX-5422)","HSP90, Her-2"]
["WYE-687","mTOR"]
["BMY 7378","α2C-, α1D-adrenoceptor"]
["ZM336372","c-Raf"]
["Trospium chloride (Sanctura)","Muscarinic receptor"]
["Cloxacillin sodium (Cloxacap)","Antibiotic"]
["Clorsulon","Antibiotic"]
["PNU-120596","α7 nAChR"]
["GSK2126458","p110, mTOR"]
["LY310762","5-HT1D receptor"]
["TG101209","JAK2 "]
["PH-797804","p38α"]
["Tolterodine tartrate (Detrol LA)","Muscarinic receptor"]
["Amoxicillin (Amox)","Antibiotic"]
["TAK-733","MEK1"]
["GW3965 HCl","Liver X receptor"]
["5-hydroxymethyl tolterodine (PNU 200577)","Muscarinic receptor"]
["A-674563","Akt1, PKA"]
["WAY-362450","Farnesoid X Receptor"]
["PF-04691502","PI3K, mTOR"]
["Azelastine HCl (Astelin)","Histamine antagonist"]
["Isoprenaline HCl","β-adrenoceptor"]
["MG-132","Proteasome, apoptosis activator "]
["URB597","FAAH"]
["MK-0752","γ-secretase"]
["AS-252424","PI3Kγ"]
["GDC-0980 (RG7422)","PI3K, mTOR"]
["ATP (Adenosine-Triphosphate)","ATP"]
["5-Aminolevulinic acid HCl","Heme biosynthesis"]
["Neomycin sulfate","Antibiotic"]
["GSK256066","PDE4B"]
["BMS-806 (BMS 378806)","HIV virus"]
["WYE-125132","mTOR"]
["GSK1120212 (Trametinib)","MEK1/2"]
["Evodiamine (Isoevodiamine)","Alkaloid"]
["Epinephrine bitartrate","α-, ß-adrenergic receptor"]
["Isoconazole nitrate","Antifungal agent"]
["NVP-BSK805 diHCl","JAK2"]
["Avasimibe (CI-1011)","ACAT"]
["Vinflunine Tartrate","Mitotic inhibitor, vinca alkaloids"]
["CP-466722","ATM"]
["Hematoxylin ","Hematoxylin "]
["L-Adrenaline (Epinephrine)","Adrenaline hormone"]
["Econazole nitrate ","Antifungal agent"]
["KX2-391","Src"]
["AZD8931","EGFR, ErbB2,3"]
["AZ 960","JAK2"]
["Eltrombopag (SB-497115-GR)","Thrombopoietin receptor"]
["Abiraterone Acetate (CB7630)","CYP17"]
["Phenytoin sodium (Dilantin)","Sodium channel"]
["Miconazole ","Antifungal agent"]
["GSK1838705A","IGF-1R, IR, ALK"]
["CYT997","Microtubuli"]
["DAPT (GSI-IX)","γ-secretase"]
["LY2157299","TGFβ receptor I (TβRI)"]
["BKM120 (NVP-BKM120)","p110α/β/δ/γ"]
["Gentamycin sulfate","Antibiotic"]
["Phenytoin (Lepitoin)","Sodium channel"]
["Secnidazole","Antiamoebic"]
["Crenolanib (CP-868569)","PDGFRα/β, FLT3"]
["A-966492","PARP1, PARP2"]
["Mubritinib (TAK 165)","HER2/ErbB2"]
["Telatinib (BAY 57-9352)","VEGFR2/3, c-Kit, PDGFRβ"]
["CX-4945","CK2"]
["Hexestrol (Bibenzyl)","Erα, Erβ"]
["Alizarin","CYP1A1, CYP1A2, CYP1B1"]
["Acetanilide (Antifebrin)","Aniline derivative"]
["Tofacitinib citrate","JAK3"]
["Aliskiren hemifumarate","Renin"]
["Irinotecan HCl Trihydrate","Topoisomerase I"]
["Ketanserin","5-HT2A serotonin receptor"]
["Itraconazole","Antifungal agent"]
["Methacycline HCl ","Antibiotic"]
["Lomefloxacin HCl","Antibiotic"]
["Fenoprofen calcium","NSAID"]
["Raf265 derivative","unknown"]