Quantitative Phospho-proteomic Analysis of TNFα/NFκB Signaling Reveals a Role for RIPK1 Phosphorylation in Suppressing Necrotic Cell Death

Supplemental Data

  • Supplemental data (.pdf, 2.1 MB) - Supplemental figures and legends
  • Table S1 (.xlsx, 17.5 MB) - Peptides identified in the 10-plex TMT experiment in DMSO-treated (n=4), TNFα-treated (n=3), and (SM+TNFα)-treated (n=3) H1299 cells
  • Table S2 (.xlsx, 355 KB) - Proteins identified in the 10-plex TMT experiment in DMSO-treated (n=4), TNFα-treated (n=3), and (SM+TNFα)-treated (n=3) H1299 cells
  • Table S3 (.xlsx, 2.8 MB) - Proteins quantified in the 10-plex TMT experiment in DMSO-treated (n=4), TNFα-treated (n=3), and (SM+TNFα)-treated (n=3) H1299 cells
  • Table S4 (.xlsx, 5.7 MB) - Phosphorylated peptides identified in the 10-plex TMT experiment in DMSO-treated (n=4), TNFα-treated (n=3), and (SM+TNFα)-treated (n=3) H1299 cells
  • Table S5 (.xlsx, 3.8 MB) - Phosphorylated peptides quantified in the 10-plex TMT experiment in DMSO-treated (n=4), TNFα-treated (n=3), and (SM+TNFα)-treated (n=3) H1299 cells
  • Table S6 (.xlsx, 227 KB) - Quantified phosphorylated peptides and their associated proteins
  • Table S7 (.xlsx, 45 KB) - Quantified phosphorylated peptides and their associated proteins
  • Table S8 (.xlsx, 10 KB) - AQUA-based quantification of RIPK1 peptides