"Supplementary Table 4. The GO enrichment of the 30 graphical analysis identified features, which also passed permutation test.",,,,,,,,,,,, Category,Term,Count,%,PValue,Genes,List Total,Pop Hits,Pop Total,Fold Enrichment,Bonferroni,Benjamini,FDR GOTERM_BP_DIRECT,GO:0000122~negative regulation of transcription from RNA polymerase II promoter,7,0.142103126,8.52E-05,"BMP2, SIN3A, EZR, IKZF1, RNF2, SMAD4, RYBP",26,377,12321,8.798918588,0.026080571,0.026080571,0.114420266 GOTERM_CC_DIRECT,GO:0031519~PcG protein complex,3,0.06090134,2.56E-04,"YY1, SCML2, RYBP",25,14,13919,119.3057143,0.018770761,0.018770761,0.267661459 GOTERM_BP_DIRECT,GO:0001702~gastrulation with mouth forming second,3,0.06090134,4.66E-04,"RNF2, SMAD4, CHRD",26,16,12321,88.85336538,0.134574758,0.069717655,0.6241953 GOTERM_BP_DIRECT,GO:0070373~negative regulation of ERK1 and ERK2 cascade,3,0.06090134,0.002940841,"EZR, PTPRR, SLC9A3R1",26,40,12321,35.54134615,0.598683063,0.26238598,3.878114396 GOTERM_BP_DIRECT,GO:0001701~in utero embryonic development,4,0.081201786,0.003665521,"BMP2, SIN3A, PTPRR, SMAD4",26,155,12321,12.2292804,0.679668605,0.247684731,4.812136833 GOTERM_BP_DIRECT,GO:0030509~BMP signaling pathway,3,0.06090134,0.004210912,"BMP2, SMAD4, SMAD1",26,48,12321,29.61778846,0.729677303,0.230202489,5.509529942 GOTERM_BP_DIRECT,GO:0060395~SMAD protein signal transduction,3,0.06090134,0.004742004,"BMP2, SMAD4, SMAD1",26,51,12321,27.87556561,0.770881914,0.217754221,6.18409189 GOTERM_BP_DIRECT,GO:0031581~hemidesmosome assembly,2,0.040600893,0.006075318,"COL17A1, PLEC",26,3,12321,315.9230769,0.848791058,0.236521552,7.857997052 GOTERM_CC_DIRECT,GO:0030056~hemidesmosome,2,0.040600893,0.006879969,"COL17A1, PLEC",25,4,13919,278.38,0.400030898,0.225423275,6.971040313 GOTERM_BP_DIRECT,GO:0008285~negative regulation of cell proliferation,4,0.081201786,0.008738172,"BMP2, SMAD4, SMAD1, SLC9A3R1",26,212,12321,8.941219158,0.93417383,0.288295317,11.11864766 GOTERM_BP_DIRECT,GO:1901522~positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus,2,0.040600893,0.012115193,"BMP2, SMAD1",26,6,12321,157.9615385,0.977146384,0.342854319,15.10020699 GOTERM_BP_DIRECT,GO:0030953~astral microtubule organization,2,0.040600893,0.012115193,"EZR, KPNB1",26,6,12321,157.9615385,0.977146384,0.342854319,15.10020699 GOTERM_BP_DIRECT,GO:0007183~SMAD protein complex assembly,2,0.040600893,0.016122185,"SMAD4, SMAD1",26,8,12321,118.4711538,0.993517209,0.395806284,19.61016506 GOTERM_BP_DIRECT,GO:0061036~positive regulation of cartilage development,2,0.040600893,0.018119826,"BMP2, SMAD1",26,9,12321,105.3076923,0.996547512,0.402698177,21.77475279 GOTERM_BP_DIRECT,GO:0030033~microvillus assembly,2,0.040600893,0.018119826,"EZR, SLC9A3R1",26,9,12321,105.3076923,0.996547512,0.402698177,21.77475279 GOTERM_BP_DIRECT,GO:1902895~positive regulation of pri-miRNA transcription from RNA polymerase II promoter,2,0.040600893,0.028049762,"BMP2, SMAD1",26,14,12321,67.6978022,0.999852209,0.520482877,31.75646405 GOTERM_CC_DIRECT,GO:0005667~transcription factor complex,3,0.06090134,0.028969696,"SIN3A, YY1, SMAD1",25,155,13919,10.776,0.886439841,0.515743643,26.48608965 GOTERM_BP_DIRECT,GO:0006607~NLS-bearing protein import into nucleus,2,0.040600893,0.030024147,"KPNA7, KPNB1",26,15,12321,63.18461538,0.999921316,0.516608587,33.59488343 GOTERM_MF_DIRECT,GO:0008139~nuclear localization sequence binding,2,0.040600893,0.037228555,"KPNA7, KPNB1",23,20,11618,50.51304348,0.811626051,0.811626051,29.87914379 GOTERM_BP_DIRECT,GO:0048015~phosphatidylinositol-mediated signaling,2,0.040600893,0.041789846,"EZR, PDGFRB",26,21,12321,45.13186813,0.99999821,0.611412838,43.63345544 GOTERM_BP_DIRECT,GO:0050714~positive regulation of protein secretion,2,0.040600893,0.045681209,"KCNN4, EZR",26,23,12321,41.20735786,0.999999493,0.619520006,46.63125652 GOTERM_CC_DIRECT,GO:0001772~immunological synapse,2,0.040600893,0.048863032,"EZR, ARHGDIA",25,29,13919,38.39724138,0.97545367,0.604180997,40.80610676 GOTERM_BP_DIRECT,GO:0010718~positive regulation of epithelial to mesenchymal transition,2,0.040600893,0.049557398,"BMP2, SMAD4",26,25,12321,37.91076923,0.999999856,0.626479703,49.47007197 GOTERM_CC_DIRECT,GO:0005737~cytoplasm,9,0.182704019,0.058627895,"SIN3A, STAT5A, PTPRR, SMAD4, PDGFRB, SMAD1, KPNB1, CDKL5, ARHGDIA",25,2557,13919,1.959655847,0.988562317,0.591052449,46.86655623 UP_KEYWORDS,Transcription regulation,3,0.06090134,0.059299999,"STAT5A, SMAD4, SMAD1",27,250,16383,7.281333333,0.949984331,0.949984331,44.35188858 GOTERM_CC_DIRECT,GO:0005654~nucleoplasm,6,0.12180268,0.060668575,"MAPK1, STAT5A, KPNA7, RYBP, KPNB1, CDKL5",25,1263,13919,2.644940618,0.990259191,0.537868218,48.05982735 GOTERM_BP_DIRECT,GO:0090002~establishment of protein localization to plasma membrane,2,0.040600893,0.064911552,"EZR, SLC9A3R1",26,33,12321,28.72027972,0.999999999,0.705903225,59.39712164 GOTERM_CC_DIRECT,GO:0005902~microvillus,2,0.040600893,0.066791824,"EZR, SLC9A3R1",25,40,13919,27.838,0.993996402,0.518462374,51.49632117 GOTERM_BP_DIRECT,GO:0071407~cellular response to organic cyclic compound,2,0.040600893,0.066813994,"BMP2, SMAD1",26,34,12321,27.87556561,1,0.696061325,60.49259655 GOTERM_BP_DIRECT,GO:0001658~branching involved in ureteric bud morphogenesis,2,0.040600893,0.066813994,"BMP2, SMAD4",26,34,12321,27.87556561,1,0.696061325,60.49259655 GOTERM_CC_DIRECT,GO:0005903~brush border,2,0.040600893,0.073230725,"EZR, PLEC",25,44,13919,25.30727273,0.996403331,0.505134074,54.88693733 GOTERM_BP_DIRECT,GO:0010862~positive regulation of pathway-restricted SMAD protein phosphorylation,2,0.040600893,0.074386673,"BMP2, SMAD4",26,38,12321,24.94129555,1,0.71668315,64.58759111 UP_KEYWORDS,Transcription,3,0.06090134,0.076386992,"STAT5A, SMAD4, SMAD1",27,289,16383,6.298731257,0.979629016,0.857273045,53.32120636 GOTERM_BP_DIRECT,GO:0043433~negative regulation of sequence-specific DNA binding transcription factor activity,2,0.040600893,0.080027431,"SUMO1, RNF2",26,41,12321,23.1163227,1,0.72552006,67.37856662 GOTERM_BP_DIRECT,GO:0045669~positive regulation of osteoblast differentiation,2,0.040600893,0.089355434,"BMP2, SMAD1",26,46,12321,20.60367893,1,0.748862053,71.55126601 GOTERM_CC_DIRECT,GO:0005925~focal adhesion,3,0.06090134,0.09001804,"EZR, PDGFRB, PLEC",25,293,13919,5.700614334,0.999070122,0.53957549,62.74291272 GOTERM_BP_DIRECT,GO:0001938~positive regulation of endothelial cell proliferation,2,0.040600893,0.091210107,"BMP2, STAT5A",26,47,12321,20.16530278,1,0.740155942,72.31962196 GOTERM_BP_DIRECT,GO:0007179~transforming growth factor beta receptor signaling pathway,2,0.040600893,0.098592603,"SMAD4, SMAD1",26,51,12321,18.58371041,1,0.753160269,75.19160842 GOTERM_MF_DIRECT,GO:0008565~protein transporter activity,2,0.040600893,0.099216851,"KPNA7, KPNB1",23,55,11618,18.36837945,0.989923931,0.899620375,62.37829307