Supporting Information

Files in this Data Supplement:

Fig. 5. Conservation of the CHIR D1 Ig-like domain sequences presented in a logo format. The arrows show sites with conserved amino acid changes between the different groups of CHIRs.

Fig. 6. Conservation of the TM region of CHIR, KIR, and LILR sequences presented in a logo format.

Fig. 7. Conservation of the CHIR CYT region presented in a logo format. The ITIM motifs are shown in brackets.

Fig. 8. Neighbor-joining tree of the CHIR, LRC, and Fc sequences. The tree was constructed with p distances for 184-aa sites after elimination of alignment gaps.

Fig. 9. Neighbor-joining tree of the CHIR D2 Ig-like domain sequences. The tree was constructed with p distances for 104-aa sites after elimination of alignment gaps.

Fig. 10. Neighbor-joining tree of the CHIR CYT region sequences. The tree was constructed with p distances for 58-aa sites after elimination of alignment gaps.