Control of Mucosal Candidiasis in the Zebrafish Swim Bladder Depends on Neutrophils That Block Filament Invasion and Drive Extracellular-Trap Production

Supplemental material

• Supplemental file 1 -

  Fig. S1. Chemical inhibition of PI3K, but not CXCR2, reduces neutrophil recruitment. Fig. S2. CXCR2 inhibition blocks neutrophil recruitment to Pseudomonas aeruginosa infection in the otic vesicle. Fig. S3. CXCR2 inhibition increases the number of macrophages recruited to the swim bladder during mucosal candidiasis. Fig. S4. C. albicans burden rank correlates with quantification by surface of the swim bladder coverage. Fig. S5. Adoptive cell transfer of murine neutrophils does not robustly reduce mpo:Rac2-D57N susceptibility. Supplemental methods.

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