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{"sheet":"Sheet1","index":0,"n_rows":117,"n_cols":7,"rows_kept":117,"cut":false,"hidden":false,"merged":[[0,0,0,5],[1,1,1,3],[1,4,1,6],[2,1,2,3],[2,4,2,6]]}
["Table S4.  Methylation Changes at TFBS (ERRBS)"]
[null,"Hypermethylation instances",null,null,"Hypomethylation instances"]
[null,"-log10(Fisher exact P-values (two-sided))",null,null,"-log10(Fisher exact P-values (two-sided))"]
["Transcription factor","p4_vs_p8_aged","p4_vs_p8_yng","p4_yng_vs_aged","p4_vs_p8_aged","p4_vs_p8_yng","p4_yng_vs_aged"]
["ARID3A",2.442974278,4.047207557,1.327421912,2.45136494,0.1800962755,0.111080084]
["ATF1",14.8068754,5.653647026,15.48017201,14.92811799,1.959120875,2.800244823]
["ATF2",0.1270481527,0.1360849995,0.2646933894,0.0367015016,0.2434140933,0.293271979]
["ATF3",8.342944147,0.0,0.0,6.417936637,0.0,0.0]
["BACH1",0.0,0.2439636473,0.9765129612,0.7521887042,2.778585762,2.945004138]
["BCL3",1.121380557,1.015531197,0.535336114,0.2434597361,0.6527656376,0.4426600517]
["BCLAF1",4.13430394,3.017276612,5.121478204,2.059882133,3.269217724,6.229147988]
["BDP1",0.2278433859,0.1613196245,1.695703397,0.7923064024,0.3864996192,0.1572684763]
["BHLHE40",0.8643871858,0.1259550157,0.860697208,1.712422191,0.8094442077,0.402264238]
["BRCA1",11.74232143,10.10846254,17.6716204,10.22694531,14.33535802,6.077274542]
["BRF1",0.1939557643,0.1984776128,1.698362417,0.3645584783,0.2015634475,0.1993255286]
["BRF2",0.1177869224,0.968704669,0.1494376916,0.2944467311,1.040271916,0.3923895165]
["CBX3",1.042407078,3.010995384,2.468521083,0.0182914522,0.1004076441,0.0183267858]
["CEBPB",4.337242168,1.82226155,3.221125528,3.279840697,4.403402904,3.400116928]
["CHD1",2.49376564,1.107599272,0.5116100586,1.651948387,2.063034103,0.5436324484]
["CREB1",28.03385827,13.66154351,39.35163999,29.57511836,28.0428718,23.09799711]
["CTBP2",48.5559552,20.95078198,36.79860288,23.4100504,11.35066514,17.52287875]
["CTCF",40.51999306,46.19246497,95.8827287,45.05354773,66.51427857,63.74714697]
["E2F4",16.28066871,14.05898576,27.03058409,11.53610701,22.5214335,28.35654732]
["E2F6",1.49660431,0.8887879105,0.5279123232,1.812676731,3.366531544,0.1323481087]
["EBF1",0.4088585631,1.051303466,0.8810015956,0.5512364992,1.63861218,3.910094889]
["EGR1",10.52870829,1.174255906,10.26680273,2.447696891,3.91721463,1.50707207]
["ELF1",2.449771647,0.5227065093,0.1697283472,1.479123618,0.0635998726,0.4585006336]
["ELK4",3.580044252,6.565431096,11.09799711,3.821023053,11.44611697,9.694648631]
["EP300",1.261766617,1.613965005,9.903089987,2.819874125,21.36451625,13.14935376]
["ESRRA",0.1902316048,0.0759208457,0.4960255635,0.3781644653,0.0791782929,1.199241693]
["EZH2",{"$error":"#NUM!"},{"$error":"#NUM!"},{"$error":"#NUM!"},{"$error":"#NUM!"},172.6798537,214.9956786]
["FOS",5.159893906,0.8225096734,0.332378032,0.1139844385,13.32697909,5.002613616]
["FOSL1",3.866461092,1.331865786,1.140543457,0.0,0.4973708026,1.221638891]
["FOSL2",4.251037139,2.43568909,0.5498510066,0.5537145357,3.847711656,1.489186989]
["FOXM1",1.870374548,0.5407824716,1.847222585,0.8442662945,1.709186584,1.560130692]
["GABPA",0.9372300502,0.5422391778,0.0188947829,1.079777507,0.0737784934,0.5759583758]
["GTF2B",5.600326279,5.238824187,6.196542884,4.554395797,3.455931956,6.204119983]
["GTF2F1",6.70333481,10.90657831,11.21395879,6.199970641,5.906578315,8.844663963]
["GTF3C2",1.267831488,0.1710309237,0.1898387498,0.690457126,1.100874706,1.042785527]
["HMGN3",0.9863497617,0.7535777475,0.4518194866,1.316232739,5.200659451,2.808828544]
["HSF1",3.903089987,0.2918273391,3.306273051,2.66514431,1.261853911,1.257817093]
["IRF1",11.7619539,12.66958623,19.09420412,8.826813732,11.27901426,15.02273379]
["IRF3",4.539102157,4.399027104,5.008773924,6.416801226,5.055517328,5.214670165]
["JUN",8.982966661,0.6733385403,0.5409650475,0.0301616482,3.492144128,2.070427821]
["JUNB",0.9862698063,1.039391298,1.938434438,1.138017786,1.93330145,0.9956141318]
["JUND",4.100726813,2.956244873,1.903889825,0.9729767454,2.467500414,2.102208018]
["KDM5B",1.32218325,7.364516253,7.600326279,1.595491271,9.653647026,8.238824187]
["MAFF",0.1895860037,0.5080391131,0.0364511003,0.2592174323,7.219682688,0.1079131924]
["MAFK",0.6949647916,0.7401434261,0.3153844086,1.524154548,6.002176919,1.767919158]
["MAX",20.89619628,15.49894074,23.30277066,16.54975089,8.463441557,14.62525165]
["MAZ",3.407823243,0.2424263416,0.381719644,2.621965678,1.390021618,0.2274612003]
["MBD4",0.2517887078,1.762129659,1.51574288,0.0,0.2884568011,0.346271465]
["MEF2A",9.002613616,1.850657701,3.725842151,4.696803943,1.066715228,2.847711656]
["MEF2C",3.723538196,0.852215502,2.693360559,3.150580586,2.177113052,3.801342913]
["MTA3",0.22896474,0.604554782,0.0411614849,1.025999814,0.7535949848,0.5292514966]
["MXI1",0.678685393,0.7995544487,0.9572158558,0.4133935688,4.13667714,2.203633845]
["MYC",20.06248211,6.034798299,15.43179828,10.70996539,7.779891912,9.995678626]
["NFATC1",0.9691332266,0.1436820414,0.371258668,0.3565562069,0.4638293131,0.4453037364]
["NFE2",0.72110699,1.05593702,2.515130967,2.761201437,0.374121894,1.791612396]
["NFIC",0.0720448114,0.4248664453,1.437980887,0.6225881029,2.207398219,0.9321706287]
["NFYA",6.906578315,8.346787486,8.04769199,3.774690718,10.97061622,12.9625735]
["NFYB",5.759450752,3.297569464,4.68613278,3.099632871,1.714037838,6.100726813]
["NR2C2",1.385999705,1.61469766,4.251037139,3.4867824,1.93129478,1.845667339]
["NR2F2",2.221125528,0.4177309075,0.6878522748,0.6294258507,4.127261173,2.415442639]
["NR3C1",1.619029407,0.1791288901,0.0354749701,1.858456166,0.6320740922,0.0]
["PBX3",14.22548303,2.062482108,2.643400564,6.581698709,2.91649738,4.488116639]
["PML",1.477360182,5.329754147,3.66756154,2.43450637,1.943781419,8.204119983]
["RAD21",4.087777943,8.958607315,19.59176003,4.351639989,17.98296666,13.11633856]
["RCOR1",3.876148359,2.872895202,2.752026734,2.885722703,0.2840033379,0.3590745575]
["RELA",4.525783736,5.396855627,4.2915791,4.454692884,7.162411562,8.511449283]
["REST",0.934801347,1.241913597,1.163087516,1.332444323,0.3173180306,1.772190396]
["RFX5",9.530177984,12.43415218,12.2873503,6.507239611,4.657577319,7.021363052]
["RUNX3",11.42136079,2.02346662,6.438898616,15.3205721,5.728158393,6.821023053]
["RXRA",0.076593281,0.9766775649,1.19174175,0.5164155555,2.582694417,3.847711656]
["SAP30",2.624153564,5.074172425,5.166215625,1.812338297,17.38404995,13.64589156]
["SETDB1",3.081969663,0.0,2.682354457,3.14327111,1.147093241,2.668775219]
["SIN3A",7.428291168,0.5745521905,0.3242427322,1.447356115,5.850780887,2.983802646]
["SIRT6",2.3341377,0.3039180812,0.7113864062,0.9167841378,0.6526094805,0.0925327435]
["SIX5",12.39040559,9.809668302,20.42596873,12.33629907,10.57024772,15.21752738]
["SMARCA4",0.2584891337,0.0425426111,0.6167628817,0.3239551163,0.5725268745,0.4732318102]
["SMARCB1",2.896880746,1.144711075,0.4071207206,0.8146533642,1.651558833,0.1148209052]
["SMARCC1",0.5784372014,0.1590744149,1.562360402,1.578807532,1.887629634,2.173212761]
["SMARCC2",1.678815973,0.039983257,1.080482603,0.9054904399,1.327551152,0.089410276]
["SMC3",2.043735497,0.6523129365,0.8255244228,1.742537426,0.0295406124,0.5120659116]
["SP1",1.783227302,0.3990771762,0.034205372,2.887394998,0.2615373536,0.2581805271]
["SP2",5.557520231,3.100179498,8.749579998,5.341035157,5.718966633,6.443697499]
["SP4",1.886123467,0.0383596782,0.2639710105,0.5386921004,5.928117993,8.131943638]
["SRF",18.02456819,5.806875402,12.93181414,15.44009337,9.454692884,7.747146969]
["STAT1",3.137272472,3.307153081,2.449160395,1.473156923,2.210771943,4.21395879]
["STAT2",1.776633874,0.0409504946,2.234182485,0.9919409044,0.0899591367,0.0892897051]
["STAT3",5.89279003,0.642787673,0.4361429262,0.5745228415,4.739928612,0.7122699122]
["STAT5A",0.2826882293,0.7269825146,1.907560089,0.3969628605,1.010301068,0.1969008468]
["SUZ12",157.0065638,104.5497509,107.8153086,106.0545314,22.53165267,48.75945075]
["TAF1",9.645891561,0.6502311331,2.682563503,3.087777943,3.576754126,3.307153081]
["TAF7",4.560667306,6.728158393,13.05060999,8.924453039,11.05948352,16.64975198]
["TBL1XR1",5.978810701,2.468010449,5.190440285,3.186419011,2.027241916,2.187220293]
["TBP",0.2788623619,0.6973163233,0.2381285183,0.9061232446,1.522473593,2.757458572]
["TCF12",0.1929875219,0.0128769428,0.1395829291,1.259574145,0.1369491053,0.1024267866]
["TCF3",9.259637311,0.6437981648,1.612129868,4.139661993,3.417936637,6.050609993]
["TEAD4",0.0662763947,0.116371493,0.2441700999,0.1383921177,6.213248578,2.835647144]
["THAP1",10.00174066,4.987162775,11.59516628,10.27083521,8.117475462,10.54668166]
["TRIM28",3.777283529,2.226506108,3.359518563,0.660693679,0.2646901939,0.3446339085]
["UBTF",0.0429494646,1.927566274,1.299945614,0.0197679451,3.899629455,2.178159073]
["USF2",1.490515211,0.195307995,0.3644509129,1.112208342,0.3542054974,0.1029274003]
["WRNIP1",7.237321436,2.41128022,8.684029655,2.26744542,2.508778424,2.950007143]
["YY1",3.801342913,0.4082744323,1.903924634,0.4110160741,0.5383649335,0.0379495166]
["ZBTB33",1.794579084,2.111539682,2.710634048,1.146922652,0.5255768395,1.673664139]
["ZBTB7A",0.7739778199,0.2246291535,2.455683858,1.347763332,2.536853863,1.240770447]
["ZEB1",1.2944185,0.0254035751,2.733063089,3.605548319,1.443938841,3.812479279]
["ZKSCAN1",6.835647144,2.386052523,4.645891561,1.06663421,2.846185136,1.675655801]
["ZNF143",3.322393047,0.8338571424,3.400116928,2.405939099,1.465276028,1.458832782]
["ZNF217",4.605548319,3.793174124,14.75696195,10.16621563,16.23657201,12.31875876]
["ZNF263",7.174573882,2.598944274,5.655607726,6.669586227,2.92628165,2.78994915]
["ZNF274",0.3738865928,0.7355458148,1.678132419,0.2936398686,2.084336396,0.9497943058]
["ZZZ3",1.433892626,0.0,2.51684079,0.7211549783,0.7449374546,0.7489436615]
["E2F1",0.0,0.1423593845,1.266610115,0.0,6.774690718,10.11350927]
["MYBL2",0.0,0.0,0.039115104,0.0,0.0,0.1607702817]