Induction of Type I Interferon through a Noncanonical Toll-Like Receptor 7 Pathway during Yersinia pestis Infection

Supplemental material

• Supplemental file 1 -

  Fig. S1. Intracellular Y. pestis stimulates IFN-β expression in macrophages. Fig. S2. Extracellular Y. pestis KIM suppresses IFN-β expression by macrophages. Fig. S3. Less severe pathology in the spleens of Tlr7^−/− mice on day 5 following infection by Y. pestis KIM D27. Fig. S4. Similar pathology in the spleens of Tlr7^−/− mice on day 3 following infection by Y. pestis CO92.

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