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["Table S1. Features of TSD cell lines compared to control cell lines."]
[null,"WT","NAT","TSD1-NR","TSD2-FCP","TSD3-FCP"]
["Valve diameter (µm) (SEM)","-","3.7 ± 0.62  (n=127)","4.62 ± 0.5 (n=148)              p = 6.189× 10-8","4.52 ± 0.57 (n=19)                  p =4.39× 10-4","5.17 ± 0.73 (n=98)                p = 3.112× 10-26"]
["Cell biovolume (µm3) (LM)","-","57.79 ± 24.28 (n=50)","127.93 ± 30.01 (n=31)                p = 1.09 × 10-9","106.68 ± 30.27 (n=6)                    p = 0.199892","152.15 ± 66.86 (n=9)                   p = 9.391 × 10-3"]
["Surface area (µm2) (LM)","-","82.6 ± 23.61 (n=50)","141.85 ± 23.52 (n=31)","123.29 ± 25.48 (n=8)","155.75 ± 46.27 (n=9)"]
["Surface area: volume ratio","-","1.52 ± 0.23 (n=50)","1.128 ± 0.09 (n=31)","1.2 ± 0.14   (n=8)","1.08 ± 0.15 (n=9)"]
["Number of fultoportulae per cell (SEM)","-","8.6 ± 1.83  (n=81)","11.44 ± 1.77 (n=27)                 p = 1.996 × 10-8","11.38 ± 1.77 (n=8)                   p = 1.063 × 10-3","13.88 ± 2.18 (n=32)                p = 4.402 × 10-12"]
["Number of central pores","-","0.69 ± 0.54 (n=115)","1.03 ± 0.64 (n=37)                p = 8.162 × 10-6","-","1.42 ± 0.71 (n=71)                p = 9.881 × 10-26"]
["Growth rate during exponential phase","1.5406 ± 0.2     p = 0.2358","1.7196 ± 0.4","1.7937 ± 0.2       p = 0.0108","1.4458 ± 0.4      p = 0.3226","1.7486 ± 0.5       p = 0.0156"]
["Si(OH)4 uptake during exponential phase (pmoles per cell)","-","40.1 ± 5.33","61.6 ± 2.48        p = 3.671× 10-4","83.3 ± 1.18        p = 9.26 × 10-5","84.9 ± 3.64        p = 1.2 × 10-6"]
["Chlorophyll a content per cell (fg)","-","91.509 ± 6.241","175.12 ± 3.325     p = 4.3 × 10-4","-","345.3 ± 3.815     p = 7.61 × 10-3"]
["Chlorophyll a content per biomass (fg/ µm3)","-","1.583 ± 0.0108","1.369 ± 0.026    p = 0.04577","-","2.27 ± 0.0025    p = 0.7217"]
["RNA content per cell (fg)","350.4 ± 95.18   p = 0.5884","374.72 ± 35.71","726.73 ± 135.48  p = 3.36 × 10-3","-","729.33 ± 169.34  p = 3.97 × 10-3"]
["RNA content per volume (fg/ µm3)","-","6.484 ± 0.618","5.681 ± 1.059   p = 0.2695","-","4.794 ± 1.113    p = 0.022"]
[" Bold text denotes values that are significantly different to the values for NAT control cells (P < 0.01) determined by student’s t-test. “SEM” denotes measurements taken from scanning electron micrographs. “LM” denotes measurements taken from light microscope images."]