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[null,"Supplementary Table 4: Summary of the mutations identified in the matching cfDNA and tissue of PDAC patients by tNGS"]
[{"$nulls":5},"tNGS",{"$nulls":10},"ddPCR for KRAS"]
[null,"Disease","Patient ID","Sample Type","Gene ID","Position","Amino Acid Change","COSMIC","Ref","Variant","Variant Allele Frequency (%)","Coverage","WT reads","MUT Reads","Mapped Reads ","Mean Read Depth","Fractional Abundance (%)"," Mutant Droplets"," WT Droplets"]
[null,"Resectable PDAC",63,"cfDNA","KRAS*","chr12:25398284","WT","--","C","--","--",606,606,0,445740,1302,0.13,1,756]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",605,605,0]
[null,null,null,"Tissue","KRAS*","chr12:25398284","p.G12V","COSM520","C","A",23.2,187,144,43,217279,946.2,2.3,23,929]
[{"$nulls":5},"chr12:25398285","WT","--","C","--","--",187,187,0]
[{"$nulls":4},"VHL","chr3:10188219","p.D121G","COSM18009","A","G",2.3,813,794,19]
[{"$nulls":4},"EGFR","chr7:55249071","p.T790M","COSM6240","C","T",4.4,136,130,6]
[{"$nulls":4},"IDH2","chr15:90631934","p.R140Q","COSM41590","C","T",7,400,372,28]
[{"$nulls":4},"TP53","chr17:7578406","p.R175H","COSM10648","C","T",3,2161,2095,"65 (1:T)"]
[null,null,69,"cfDNA","KRAS*","chr12:25398284","WT","--","C","--","--",482,482,0,206923,868.5,0,0,614]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",482,482,0]
[null,null,null,"Tissue","KRAS*     ","chr12:25398284","p.G12V     ","COSM520","C","A",19.8,440,353,"86 (1:T)",222772,999.6,25,149,441]
[{"$nulls":5},"chr12:25398285","WT","--","C","--","--",439,439,0]
[{"$nulls":4},"PTEN","chr10:89711899","p.R173C","COSM5089","C","T",2.9,522,507,15]
[{"$nulls":4},"ATM","chr11:108236086","p.R3008C","COSM21642","C","T",3,922,894,28]
[{"$nulls":4},"TP53","chr17:7577529","p.I251T","COSM11213","A","G",1.6,1901,1868,33]
[{"$nulls":4},"TP53","chr17:7577538","p.R248Q","COSM10662","C","T",2.3,1902,1858,44]
[{"$nulls":4},"TP53","chr17:7578461","p.V157I","COSM43625","C","T",4,1322,1269,53]
[null,null,"72**","cfDNA","KRAS","chr12:25398284","WT","--","C","--","--",507,506,1,231054,970.7,"na","na","na"]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",507,507,0]
[null,null,null,"Tissue","KRAS","chr12:25398284","WT","--","C","--","--",111,111,0,209852,865.1,2.5,11,422]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",111,111,0]
[{"$nulls":4},"TP53","chr17:7578406","p.R175H","COSM10648","C","T",1.7,814,800,14]
[{"$nulls":4},"TP53","chr17:7578461","p.V157I","COSM43625","C","T",14.1,803,690,113]
[null,null,102,"cfDNA","KRAS*","chr12:25398284","WT","--","C","--","--",1448,1448,0,328787,1448,0,0,626]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",1448,1447,1]
[null,null,null,"Tissue","KRAS*","chr12:25398284","p.G12D","COSM521","C","T",13.3,136,118,18,347075,1346,5.1,15,277]
[{"$nulls":5},"chr12:25398285","WT","--","C","--","--",null,136,0]
[null,"Primary Non-Resectable PDAC  ",34,"cfDNA","KRAS*","chr12:25398284","WT","--","C","--","--",1257,1256,1,575250,2303,0.13,1,722]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",1258,1258,0]
[null,null,null,"Tissue","KRAS*","chr12:25398284","p.G12D","COSM521","C","T",3.8,104,100,4,189307,258.4,4.1,45,993]
[{"$nulls":5},"chr12:25398285","WT","--","C","--","--",104,104,0]
[null,null,80,"cfDNA","KRAS*","chr12:25398284","WT","--","C","--","--",464,463,1,498846,1514,0,0,573]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",462,462,0]
[null,null,null,"Tissue","KRAS*","chr12:25398284","WT","--","C","--","--",1798,1796,2,634630,2771,0,0,763]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",1798,1797,1]
[null,"Metastatic Non-Resectable PDAC ",12,"cfDNA","KRAS","chr12:25398284","WT","--","C","--","--",431,431,0,174759,639.3,"na","na","na"]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",433,433,0]
[null,null,null,"Tissue","KRAS*","chr12:25398284","WT","--","C","--","--",298,298,0,378912,1544,0,0,739]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",298,298,0]
[null,null,15,"cfDNA","KRAS*","chr12:25398285","WT","--","C","--","--",2000,1999,1,741713,3115,0,0,665]
[{"$nulls":5},"chr12:25398284",null,null,"C","--","--",2001,2000,1]
[null,null,null,"Tissue","KRAS*","chr12:25398284","p.G12V   ","COSM520","C","A",7.4,27,25,2,50873,63.31,6.2,51,742]
[{"$nulls":5},"chr12:25398285","WT","--","C","--","--",27,27,0]
[null,null,41,"cfDNA","KRAS*","chr12:25398284","WT","--","C","--","--",388,388,0,109116,463.8,0.23,1,428]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",387,387,0]
[null,null,null,"Tissue","KRAS*                    ","chr12:25398284","p.G12D                   ","COSM521","C","T",25.2,167,125,42,268037,1056,16.3,147,730]
[{"$nulls":5},"chr12:25398285","WT","--","C","--","--",166,166,0]
[{"$nulls":4},"FBXW7","chr4:153249384","p.R385H","COSM117308","C","T",7.7,156,144,12]
[{"$nulls":4},"EGFR","chr7:55242465","p.E746_A750delELREA","COSM6223","GGAATTAA","-",7.8,256,256,21]
[{"$nulls":4},"CDKN2A","chr9:21971120","p.R80*","COSM12475","G","A",31.1,475,344,132]
[{"$nulls":4},"PTEN","chr10:89711900","p.R173H","COSM5039","G","A",17.4,23,19,4]
[null,null,68,"cfDNA","KRAS*","chr12:25398284","WT","--","C","--","--",1338,1338,0,459777,1956,0.15,1,630]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",1337,1336,1]
[null,null,null,"Tissue","KRAS","chr12:25398284","p.G12D","COSM521","C","T",7.2,303,280,23,531759,1875,0.8,9,1039]
[{"$nulls":5},"chr12:25398285","WT","--","C","--","--",303,303,0]
[null,null,73,"cfDNA","KRAS*","chr12:25398284","WT","--","C","--","--",930,930,0,329811,1403,0,0,745]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",930,930,0]
[null,null,null,"Tissue","KRAS*","chr12:25398284","WT","--","C","--","--",241,241,0,369118,1552,0,0,1290]
[{"$nulls":5},"chr12:25398285",null,null,"C","--","--",240,240,0]
[{"$nulls":4}," TP53","chr17:7577091","p.R283C","COSM10911","G","A",2.5,357,347,10]