Cell Invasion and Pyruvate Oxidase-Derived H₂O₂ Are Critical for Streptococcus pneumoniae-Mediated Cardiomyocyte Killing

Supplemental material

• Supplemental file 1 -

  Table S1. Strains used in this study. Table S2. Primers used in this study. Fig. S1. Streptococcus pneumoniae invades HL-1 cardiomyocytes through clathrin-mediated endocytosis. Fig. S2. ΔspxB and Δply mutants are not impaired in adhesion and invasion of HL-1. Fig. S3. Inflammatory response of HL-1 upon Streptococcus pneumoniae infection.

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• Supplemental file 2 -

  Supplemental materials and methods.

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