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{"sheet":"TableS4","index":0,"n_rows":987,"n_cols":12,"rows_kept":987,"cut":false,"hidden":false,"merged":[]}
["GeneSet","Source","Concept","DESC","P.value.log10","FDR","NumHit","NumSet","NumConcept","OverlapGenes","FDR (global)","FDR (diseae modules)"]
["TR1","h.all.v5.0.entrez","HALLMARK_INTERFERON_ALPHA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_ALPHA_RESPONSE",75.44779563586376,4.450603954554492E-73,61.0,271.0,91.0,"RIPK2,IFIT2,CCRL2,TAP1,IFIH1,ISG20,PLSCR1,IRF9,STAT2,CMPK2,IFITM3,MX1,ISG15,OAS1,IFIT3,IFI44,IFI35,IRF7,RSAD2,IFI44L,IFITM1,IFI27,OASL,EIF2AK2,SP110,DDX60,UBE2L6,BST2,LGALS3BP,ADAR,PSMB9,HERC6,RTP4,SAMD9L,LY6E,HELZ2,TRIM21,PARP14,TRIM26,PARP12,RNF31,TRIM14,TDRD7,DHX58,PARP9,PNPT1,PSME1,EPSTI1,UBA7,TRIM5,LAP3,LAMP3,TMEM140,IFI30,CNP,FAM46A,CMTR1,MOV10,TRAFD1,BATF2,NUB1",1.316637003222367E-72,3.0669225968885036E-74]
["TR17","h.all.v5.0.entrez","HALLMARK_HEME_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HEME_METABOLISM",66.36472351200415,2.694393844677966E-64,87.0,531.0,170.0,"MAP2K3,MXI1,SLC2A1,BNIP3L,FOXO3,SELENBP1,EPB41,E2F2,PPP2R5B,BLVRB,CA2,MYL4,SLC6A8,BPGM,CTSB,HMBS,HDGF,RCL1,RAP1GAP,SMOX,PRDX2,BSG,ALAS2,PPOX,FECH,GYPB,RHD,GYPA,GYPE,GYPC,EPB42,SLC4A1,RHCE,RHAG,TAL1,MARCH8,SPTB,HBQ1,DCAF11,ERMAP,EIF2AK1,MPP1,GLRX5,TSPAN5,OSBP2,ANK1,AHSP,KEL,RANBP10,TRIM10,XK,SNCA,MARK3,UBAC1,CA1,KLF1,NARF,FBXO7,HBD,NUDT4,FBXO9,RAD23A,TMCC2,GATA1,RBM38,RNF123,TNS1,CTSE,DMTN,MKRN1,HBB,SLC25A37,BMP2K,HAGH,KDM7A,OPTN,KLF3,ADIPOR1,DCAF10,SLC25A38,FAM46C,TRIM58,MARCH2,SYNJ1,ABCG2,PQLC1,KHNYN",7.970915123838887E-64,1.5570487506263828E-63]
["TR1","h.all.v5.0.entrez","HALLMARK_INTERFERON_GAMMA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_GAMMA_RESPONSE",65.21008820784807,2.5645142864107375E-63,71.0,271.0,183.0,"TNFAIP3,RIPK2,IFIT2,DDX58,TAP1,IFIH1,ISG20,MT2A,PLSCR1,STAT1,MYD88,IRF9,STAT2,CD38,SOCS1,CMPK2,PML,TNFSF10,IFITM3,JAK2,MX1,ISG15,IFIT3,IFI44,IFI35,IRF7,RSAD2,IFI44L,IFI27,OASL,EIF2AK2,SP110,DDX60,UBE2L6,BST2,LGALS3BP,ADAR,PSMB9,HERC6,RTP4,SAMD9L,LY6E,HELZ2,TRIM21,PARP14,TRIM26,PARP12,RNF31,TRIM14,TDRD7,DHX58,PNPT1,PSME1,EPSTI1,LAP3,IFI30,CMTR1,TRAFD1,BATF2,IFIT1,OAS2,MX2,OAS3,XAF1,SERPING1,RNF213,ZBP1,TOR1B,IRF5,LYSMD2,APOL6",7.586688097298324E-63,2.6508200556649074E-64]
["TR1","IPA","Activation of IRF by Cytosolic Pattern Recognition Receptors","Activation of IRF by Cytosolic Pattern Recognition Receptors",9.54715066255795,2.069827547756614E-6,12.0,271.0,40.0,"REL,ADAR,IFIT2,IRF7,STAT1,STAT2,ISG15,IRF9,DDX58,IFIH1,DHX58,ZBP1",6.377429176750089E-6,1.4752060373265333E-7]
["TR18","IPA","EIF2 Signaling","EIF2 Signaling",7.801676077631634,5.1789874456598246E-5,48.0,2408.0,96.0,"ATM,NRAS,PIK3C3,PIK3CG,MAP2K2,RRAS2,PPP1CC,PDPK1,INSR,SOS1,EIF4E,RPL11,EIF4A2,EIF5,FAU,EIF3E,RPL4,RPL7,RPL22,RPL24,RPL27,RPL30,RPL31,RPL34,RPL35A,RPL39,RPLP0,RPS2,RPS7,RPS9,RPS14,RPS15A,RPS17,RPS18,RPS21,RPS23,RPS24,RPS25,RPS27A,RPS29,EIF3J,EIF2S2,RPL23,PAIP1,RPL13A,RPL26L1,EIF2A,RPL22L1",1.5957187195508882E-4,3.4670192910446E-4]
["TR1","IPA","Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses","Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",7.671718712351151,5.1789874456598246E-5,13.0,271.0,68.0,"PRKCE,REL,IRF7,DDX58,IFIH1,C1QA,MYD88,TLR7,EIF2AK2,OAS1,OAS2,OAS3,RIPK2",1.5957187195508882E-4,5.53674644684027E-6]
["PR6","IPA","B Cell Receptor Signaling","B Cell Receptor Signaling",6.980771663592167,0.0015871374212720827,13.0,78.0,33.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PTPN6,PTPN11,PDPK1,CSK,BTK,CAMK2A,CAMK2B,CAMK2D,LYN",5.874415376415372E-4,0.0011477060646448538]
["PR1","ADAMs","ADAMs","ADAMs",6.958443392927739,2.28886375522761E-5,13.0,83.0,31.0,"DLL1,DSG2,EPHB2,FCER2,LAG3,NOTCH2,TNFSF8,CX3CL1,ICAM1,IL6R,TNFRSF1A,TNFRSF1B,VCAM1",2.640996640647241E-5,5.502076334681751E-7]
["TR14","IPA","PI3K Signaling in B Lymphocytes","PI3K Signaling in B Lymphocytes",6.6432502547604475,4.1473871641841304E-4,10.0,120.0,99.0,"VAV2,CD40,IGH,IGL,CD79A,CD79B,CD19,BLNK,CR2,BLK",0.0010222945553822287,0.0016644119540475788]
["TR24","IPA","Sertoli Cell-Sertoli Cell Junction Signaling","Sertoli Cell-Sertoli Cell Junction Signaling",5.637542058215178,0.0033618068887111296,9.0,108.0,110.0,"TUBB1,PRKAR2B,ITGA2B,ITGB3,ITGB5,GUCY1A3,GUCY1B3,CLDN5,JAM3",0.008631832380553981,0.01264824549001104]
["PR1","ADAMs","ADAM17","ADAM17",5.5920743064279295,2.660474084640822E-4,10.0,83.0,23.0,"DLL1,DSG2,LAG3,TNFSF8,CX3CL1,ICAM1,IL6R,TNFRSF1A,TNFRSF1B,VCAM1",3.0697777899701804E-4,1.0232592633233934E-5]
["TR24","IPA","Ephrin Receptor Signaling","Ephrin Receptor Signaling",5.383517337532043,0.005028242765262461,9.0,108.0,118.0,"GNAZ,GNG7,GNG11,EGF,ITGA2B,ITGB3,ITGB5,PDGFA,NCK2",0.013279475724048423,0.015179542377097644]
["PR1","ADAMs","ADAM10","ADAM10",5.3737324298835105,2.9323084397427074E-4,8.0,83.0,15.0,"DLL1,DSG2,EPHB2,FCER2,LAG3,NOTCH2,TNFSF8,CX3CL1",3.383432815087741E-4,1.268787305657903E-5]
["TR24","IPA","Integrin Signaling","Integrin Signaling",5.234730736729945,0.00607094150802162,9.0,108.0,123.0,"ITGA2B,ITGB3,ITGB5,MYLK,VCL,NCK2,CTTN,LIMS1,PARVB",0.01331913007951425,0.015179542377097644]
["PR6","IPA","Protein Kinase A Signaling","Protein Kinase A Signaling",5.185229133797243,0.020991454595068376,13.0,78.0,45.0,"PRKCB,PRKCQ,MAPK1,MAPK3,YWHAB,ACP1,PTPN6,PTPN11,PRKACA,CAMK2A,CAMK2B,CAMK2D,DUSP3",0.01331913007951425,0.015179542377097644]
["TR1","pSS GWAS","nearby genes+cis eGenes+trans eGenes","nearby genes+cis eGenes+trans eGenes",5.167623230615868,8.701352025967177E-4,6.0,271.0,19.0,"IFI6,GTF2I,IFIT1,MX1,HERC5,TNFAIP3",0.001006093828002455,2.7191725081147434E-5]
["PR6","IPA","G-Protein Coupled Receptor Signaling","G-Protein Coupled Receptor Signaling",5.143473197347668,0.020991454595068376,10.0,78.0,27.0,"PRKCB,MAPK1,MAPK3,SRC,PDPK1,PRKACA,FYN,CAMK2A,CAMK2B,CAMK2D",0.01331913007951425,0.015179542377097644]
["PR6","IPA","PI3K Signaling in B Lymphocytes","PI3K Signaling in B Lymphocytes",5.143473197347668,0.020991454595068376,10.0,78.0,27.0,"PRKCB,MAPK1,MAPK3,PDPK1,FYN,BTK,CAMK2A,CAMK2B,CAMK2D,LYN",0.01331913007951425,0.015179542377097644]
["TR14","IPA","FcγRIIB Signaling in B Lymphocytes","FcγRIIB Signaling in B Lymphocytes",5.121112307510075,0.006900531311017137,6.0,120.0,41.0,"IGH,IGL,CD79A,CD79B,CACNB2,BLNK",0.01331913007951425,0.015179542377097644]
["PR6","IPA","Melatonin Signaling","Melatonin Signaling",5.105275754398118,0.020991454595068376,8.0,78.0,17.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PRKACA,CAMK2A,CAMK2B,CAMK2D",0.01331913007951425,0.015179542377097644]
["PR6","IPA","Neuropathic Pain Signaling In Dorsal Horn Neurons","Neuropathic Pain Signaling In Dorsal Horn Neurons",5.081192410799232,0.020991454595068376,9.0,78.0,22.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,PRKACA,CAMK2A,CAMK2B,CAMK2D",0.01331913007951425,0.015179542377097644]
["TR29","h.all.v5.0.entrez","HALLMARK_ESTROGEN_RESPONSE_EARLY","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ESTROGEN_RESPONSE_EARLY",5.068818898647175,0.0026627825079531082,9.0,121.0,115.0,"MYC,FLNB,TIAM1,FAM102A,TJP3,AQP3,BCL11B,DHRS3,ABLIM1",0.007877398252694607,0.015387810454613626]
["TR14","IPA","Altered T Cell and B Cell Signaling in Rheumatoid Arthritis","Altered T Cell and B Cell Signaling in Rheumatoid Arthritis",4.936695018877508,0.009065204036958607,7.0,120.0,66.0,"CD40,HLA-DOA,HLA-DOB,IGH,IGL,CD79A,CD79B",0.01733844036159149,0.019471078053665325]
["TR24","IPA","Relaxin Signaling","Relaxin Signaling",4.905707241805766,0.009065204036958607,7.0,108.0,74.0,"GNAZ,GNG7,GNG11,PRKAR2B,GUCY1A3,GUCY1B3,PDE5A",0.017456978717005005,0.019471078053665325]
["PR6","IPA","G Beta Gamma Signaling","G Beta Gamma Signaling",4.876151078987826,0.027188872124771123,8.0,78.0,18.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,PDPK1,PRKACA,BTK",0.017587183970041647,0.019471078053665325]
["PR52","IPA","Intrinsic Prothrombin Activation Pathway","Intrinsic Prothrombin Activation Pathway",4.843905015956066,0.027188872124771123,3.0,5.0,13.0,"F9,F10,PROS1",0.01789034789148973,0.01966107849907713]
["TR24","IPA","Signaling by Rho Family GTPases","Signaling by Rho Family GTPases",4.752596813010172,0.01172452689357027,9.0,108.0,141.0,"GNAZ,GNG7,GNG11,ITGA2B,ITGB3,ITGB5,MYLK,DIAPH3,WASF3",0.020914423261787694,0.022834242102125542]
["PR6","IPA","Melanocyte Development and Pigmentation Signaling","Melanocyte Development and Pigmentation Signaling",4.664937474965493,0.03649271796554384,8.0,78.0,19.0,"MAPK1,MAPK3,SRC,PTPN6,PTPN11,PRKACA,CRK,RPS6KA3",0.024312456199910522,0.026388964914493624]
["TR14","IPA","Autoimmune Thyroid Disease Signaling","Autoimmune Thyroid Disease Signaling",4.487152021889029,0.019803937970985785,5.0,120.0,32.0,"CD40,HLA-DOA,HLA-DOB,IGH,IGL",0.03468473774186626,0.03727066391870647]
["PR6","IPA","Synaptic Long Term Potentiation","Synaptic Long Term Potentiation",4.46923521101297,0.051540779685030916,8.0,78.0,20.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PRKACA,CAMK2A,CAMK2B,CAMK2D",0.03468473774186626,0.03727066391870647]
["PR6","IPA","GM-CSF Signaling","GM-CSF Signaling",4.287104615016802,0.07126706850254597,8.0,78.0,21.0,"PRKCB,MAPK1,MAPK3,PTPN11,CAMK2A,CAMK2B,CAMK2D,LYN",0.05046192988989999,0.053989390672747606]
["TR14","IPA","Allograft Rejection Signaling","Allograft Rejection Signaling",4.231163141200874,0.029570201118009197,5.0,120.0,36.0,"CD40,HLA-DOA,HLA-DOB,IGH,IGL",0.05342332455886371,0.05672560185443327]
["TR24","IPA","Clathrin-mediated Endocytosis Signaling","Clathrin-mediated Endocytosis Signaling",4.226125387346764,0.029570201118009197,7.0,108.0,94.0,"EGF,ITGB3,ITGB5,PDGFA,CTTN,CLU,STON2",0.05342332455886371,0.05672560185443327]
["TR24","IPA","Phospholipase C Signaling","Phospholipase C Signaling",4.192556892564676,0.029570201118009197,9.0,108.0,166.0,"GNG7,GNG11,ITGA2B,ITGB3,ITGB5,TRB,CALM3,PLA2G12A,GRAP2",0.05399107546563083,0.0569615453115335]
["TR24","IPA","Actin Cytoskeleton Signaling","Actin Cytoskeleton Signaling",4.1881105643288965,0.029570201118009197,8.0,108.0,129.0,"EGF,ITGA2B,ITGB3,ITGB5,MYLK,PDGFA,VCL,DIAPH3",0.05399107546563083,0.0569615453115335]
["TR24","IPA","PAK Signaling","PAK Signaling",4.13713217155236,0.03129707368606848,6.0,108.0,67.0,"ITGA2B,ITGB3,ITGB5,MYLK,PDGFA,NCK2",0.05724284275091378,0.05991291434338777]
["PR6","IPA","CREB Signaling in Neurons","CREB Signaling in Neurons",4.116953858948827,0.08700463391457049,8.0,78.0,22.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PRKACA,CAMK2A,CAMK2B,CAMK2D",0.05724284275091378,0.05991291434338777]
["PR6","IPA","Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes","Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes",4.116953858948827,0.08700463391457049,8.0,78.0,22.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,CRK,FYN,LYN",0.05724284275091378,0.05991291434338777]
["PR6","IPA","GNRH Signaling","GNRH Signaling",4.095715775407814,0.08700463391457049,9.0,78.0,28.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,PRKACA,CAMK2A,CAMK2B,CAMK2D",0.05817264859783134,0.060746122621578816]
["PR6","IPA","Phospholipase C Signaling","Phospholipase C Signaling",4.015134469338015,0.09469787296524199,10.0,78.0,35.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,FYN,BTK,LYN,RPS6KA3,PEBP1",0.06784406463610683,0.0706878306644248]
["PR51","h.all.v5.0.entrez","HALLMARK_UV_RESPONSE_DN","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UV_RESPONSE_DN",4.000925988121301,0.24387945366391087,3.0,5.0,24.0,"PRKCA,NRP1,IGFBP5",0.07368272855377729,0.11994398662193974]
["PR52","IPA","Coagulation System","Coagulation System",4.000925988121301,0.09469787296524199,3.0,5.0,24.0,"F9,F10,PROS1",0.06797612109265379,0.0706878306644248]
["PR51","IPA","VDR/RXR Activation","VDR/RXR Activation",3.9460353051089583,0.10113511405996285,3.0,5.0,25.0,"PRKCA,IGFBP3,IGFBP5",0.0748655612509209,0.07770465782415978]
["TR24","IPA","CCR3 Signaling in Eosinophils","CCR3 Signaling in Eosinophils",3.9275278938348657,0.04789436574713407,6.0,108.0,73.0,"GNAZ,GNG7,GNG11,MYLK,CALM3,PLA2G12A",0.07589276376848501,0.07863040309562382]
["TR24","IPA","RhoGDI Signaling","RhoGDI Signaling",3.868939771087687,0.051926787248204896,7.0,108.0,107.0,"GNAZ,GNG7,GNG11,ITGA2B,ITGB3,ITGB5,ARHGAP6",0.08444112972653693,0.08734009252225643]
["PR6","IPA","Breast Cancer Regulation by Stathmin1","Breast Cancer Regulation by Stathmin1",3.8075081311788037,0.13140308420170765,8.0,78.0,24.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PRKACA,CAMK2A,CAMK2B,CAMK2D",0.09464255402446915,0.0977363599338608]
["TR13","IPA","Calcium-induced T Lymphocyte Apoptosis","Calcium-induced T Lymphocyte Apoptosis",3.7887227666059475,0.05867272896338615,6.0,172.0,49.0,"PRKCH,PPP3CC,CD247,NFATC2,ZAP70,ATP2A2",0.09622544843067159,0.09922179246543449]
["TR11","IPA","Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis","Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",3.769333150799563,0.05867272896338615,29.0,787.0,184.0,"FOS,PDIA3,PIK3CG,PRKCQ,RAF1,MAP2K4,TNFRSF1A,GNAQ,CREB5,TRAF6,CEBPB,IL1R1,IL1RAP,IL6R,TLR1,TLR2,TLR4,TLR6,TLR8,WNT7A,CAMK2G,C5AR1,FCGR3A,IL1R2,F2RL1,IRAK4,TRAF3IP2,IL17RA,CEBPD",0.09803892692286204,0.10094793999929784]
["TR24","IPA","Regulation of Cellular Mechanics by Calpain Protease","Regulation of Cellular Mechanics by Calpain Protease",3.752225856074266,0.05867272896338615,5.0,108.0,50.0,"EGF,ITGA2B,ITGB3,ITGB5,VCL",0.0994284019878435,0.1022404807854019]
["PR6","IPA","p70S6K Signaling","p70S6K Signaling",3.7090823105431086,0.15615298249220927,9.0,78.0,31.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,YWHAB,PDPK1,BTK,LYN",0.10713469551079509,0.11002349033910423]
["TR22","IPA","Molecular Mechanisms of Cancer","Molecular Mechanisms of Cancer",3.677005423059381,0.0667346775296676,60.0,1644.0,239.0,"ATM,BAD,CDKN1B,KRAS,PIK3C2A,PIK3CA,PRKCA,MAPK8,MRAS,PLCB1,PRKD3,PTPN11,RASA1,NFKB1,NFKB2,REL,GNAI3,GNB1,GNG3,PRKAG1,PRKAR1B,GNG2,GNB4,CDK2,ABL1,FANCD2,PTK2,APC2,RHOB,FNBP1,RHOF,RHOT1,FAS,TGFB1,PSEN1,PSEN2,BIRC2,XIAP,CASP3,SMAD2,SMAD4,TGFBR1,BCL2L11,TFDP1,FZD2,FZD3,FZD6,FZD8,STK36,SMAD9,CTNNB1,AXIN1,ARHGEF10,CDKN2B,CDKN2C,LAMTOR3,TAB2,PMAIP1,RALBP1,HHAT",0.11260083042873902,0.11549599412926441]
["PR6","IPA","Thrombin Signaling","Thrombin Signaling",3.591855269719364,0.19431258514988728,9.0,78.0,32.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,PDPK1,CAMK2A,CAMK2B,CAMK2D",0.13380507370578174,0.13708603311224674]
["TR14","IPA","Dendritic Cell Maturation","Dendritic Cell Maturation",3.5350083586806993,0.0886880742676623,7.0,120.0,109.0,"CD40,HLA-DOA,HLA-DOB,IGH,IGL,CD83,IRF8",0.14474594386356743,0.1478248975384395]
["PR6","IPA","PDGF Signaling","PDGF Signaling",3.5325885347759742,0.20442379273439581,8.0,78.0,26.0,"PRKCB,MAPK1,MAPK3,SRC,ACP1,CRK,CSNK2A1,SPHK1",0.14474594386356743,0.1478248975384395]
["PR6","IPA","Growth Hormone Signaling","Growth Hormone Signaling",3.5284320726422407,0.20442379273439581,7.0,78.0,20.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PTPN6,PDPK1,RPS6KA3",0.14474594386356743,0.1478248975384395]
["PR1","h.all.v5.0.entrez","HALLMARK_INTERFERON_GAMMA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_GAMMA_RESPONSE",3.508167317181566,0.3792310501905458,10.0,83.0,37.0,"ICAM1,CXCL10,NAMPT,CXCL11,B2M,VCAM1,SLAMF7,GZMA,C1R,IL18BP",0.1655626854170424,0.00889630941527194]
["TR11","h.all.v5.0.entrez","HALLMARK_TNFA_SIGNALING_VIA_NFKB","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TNFA_SIGNALING_VIA_NFKB",3.485907887485452,0.07461980187810364,25.0,787.0,155.0,"PPP1R15A,SOD2,DUSP1,ETS2,PTX3,DUSP2,CFLAR,NFIL3,TRIB1,TIPARP,LITAF,FOSL2,CD69,IL7R,BTG3,FOS,TLR2,CEBPB,F2RL1,DENND5A,B4GALT5,BCL6,CEBPD,PDLIM5,MXD1",0.1655626854170424,0.25872981305042464]
["PR6","IPA","Neuregulin Signaling","Neuregulin Signaling",3.479748847833751,0.2187305833604788,9.0,78.0,33.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,PTPN11,PDPK1,CRK,AREG",0.15847092799349535,0.16168546283179758]
["TR22","IPA","Signaling by Rho Family GTPases","Signaling by Rho Family GTPases",3.4651576327454965,0.09999704902811163,39.0,1644.0,141.0,"ATM,PIK3C2A,PIK3CA,MAPK8,VIM,MRAS,PPP1R12A,PIP4K2B,PIP5K1C,PIKFYVE,NFKB1,NFKB2,REL,GNAI3,GNB1,GNG3,GNG2,GNB4,ACTA2,ITGA2,ITGB8,MSN,MYL5,PTK2,RDX,ROCK1,ITGA10,ROCK2,ACTR2,RHOB,FNBP1,RHOF,RHOT1,MAP2K7,MAP3K9,ARHGEF10,CLIP1,SEPT7,KIAA1804",0.16047132433810404,0.16357497829791573]
["TR28","h.all.v5.0.entrez","HALLMARK_MITOTIC_SPINDLE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MITOTIC_SPINDLE",3.445209243345067,0.07461980187810364,11.0,213.0,153.0,"KIF3B,TUBGCP2,RABGAP1,NCK1,WASL,NCK2,RANBP9,PCM1,SSH2,STAU1,ARFGEF1",0.1655626854170424,0.25872981305042464]
["PR6","IPA","Calcium Signaling","Calcium Signaling",3.4415244935055482,0.2289024599112444,6.0,78.0,15.0,"MAPK1,MAPK3,PRKACA,CAMK2A,CAMK2B,CAMK2D",0.1659876335607226,0.16904797949636552]
["TR16","IPA","Hereditary Breast Cancer Signaling","Hereditary Breast Cancer Signaling",3.3863646092631963,0.11117078802646983,20.0,1114.0,82.0,"ATM,PIK3CD,PIK3R6,CREBBP,CHEK1,BLM,CCNB1,POLR2D,POLR2F,POLR2H,ATR,HDAC5,HDAC7,HDAC8,FANCC,NPM1,RFC3,RFC4,RFC5,FANCM",0.17760960042890372,0.18017431612083493]
["PR6","IPA","Erythropoietin Signaling","Erythropoietin Signaling",3.378337871621903,0.24438524167196346,7.0,78.0,21.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,PTPN6,PDPK1",0.17760960042890372,0.18017431612083493]
["PR6","IPA","cAMP-mediated signaling","cAMP-mediated signaling",3.378337871621903,0.24438524167196346,7.0,78.0,21.0,"MAPK1,MAPK3,SRC,PRKACA,CAMK2A,CAMK2B,CAMK2D",0.17760960042890372,0.18017431612083493]
["TR24","IPA","α-Adrenergic Signaling","α-Adrenergic Signaling",3.377447069163532,0.11117078802646983,5.0,108.0,60.0,"GNAZ,GNG7,GNG11,PRKAR2B,CALM3",0.17760960042890372,0.18017431612083493]
["TR14","IPA","B Cell Receptor Signaling","B Cell Receptor Signaling",3.3699361098397556,0.11117078802646983,7.0,120.0,116.0,"VAV2,CD79A,CD79B,CD19,EBF1,PAX5,BLNK",0.17760960042890372,0.18017431612083493]
["TR24","IPA","Cdc42 Signaling","Cdc42 Signaling",3.3507551480837994,0.11218419588181155,6.0,108.0,93.0,"ITGA2B,ITGB3,ITGB5,MYLK,DIAPH3,TRB",0.18225458776732112,0.18475717711791648]
["TR24","IPA","Paxillin Signaling","Paxillin Signaling",3.3110706532026786,0.11882092183670315,5.0,108.0,62.0,"ITGA2B,ITGB3,ITGB5,VCL,NCK2",0.19612710899972735,0.19868630022036435]
["TR20","IPA","PI3K Signaling in B Lymphocytes","PI3K Signaling in B Lymphocytes",3.2691352763655757,0.12504953079636208,5.0,69.0,99.0,"KRAS,PIK3CB,PPP3R1,REL,ATF7",0.2030624371067021,0.20466257324048648]
["PR6","IPA","Androgen Signaling","Androgen Signaling",3.2631560095244336,0.27015866349459544,6.0,78.0,16.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,PRKACA",0.2030624371067021,0.20466257324048648]
["TR31","IPA","Protein Kinase A Signaling","Protein Kinase A Signaling",3.260852780465585,0.12504953079636208,13.0,229.0,199.0,"DUSP8,PTPN7,PTPN12,CHUK,GNA13,GNG10,CREB1,CALM1,CAMK2D,PDE4B,AKAP1,TDP2,PTGS2",0.2030624371067021,0.20466257324048648]
["TR1","h.all.v5.0.entrez","HALLMARK_IL6_JAK_STAT3_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_IL6_JAK_STAT3_SIGNALING",3.2488856756616435,0.10051499830557488,8.0,271.0,71.0,"STAT1,MYD88,IRF9,BAK1,STAT2,CD38,SOCS1,CCR1",0.23127756554569778,0.012121400036048894]
["PR6","IPA","FAK Signaling","FAK Signaling",3.237994451749292,0.27015866349459544,7.0,78.0,22.0,"MAPK1,MAPK3,SRC,PDPK1,CRK,CSK,FYN",0.2030624371067021,0.20466257324048648]
["PR6","IPA","Insulin Receptor Signaling","Insulin Receptor Signaling",3.237994451749292,0.27015866349459544,7.0,78.0,22.0,"MAPK1,MAPK3,PTPN11,PDPK1,PRKACA,CRK,FYN",0.2030624371067021,0.20466257324048648]
["PR6","IPA","PKCθ Signaling in T Lymphocytes","PKCθ Signaling in T Lymphocytes",3.237994451749292,0.27015866349459544,7.0,78.0,22.0,"PRKCQ,MAPK1,MAPK3,FYN,CAMK2A,CAMK2B,CAMK2D",0.2030624371067021,0.20466257324048648]
["PR6","IPA","Prolactin Signaling","Prolactin Signaling",3.237994451749292,0.27015866349459544,7.0,78.0,22.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PTPN11,PDPK1,FYN",0.2030624371067021,0.20466257324048648]
["PR49","IPA","Crosstalk between Dendritic Cells and Natural Killer Cells","Crosstalk between Dendritic Cells and Natural Killer Cells",3.2374885026196507,0.27015866349459544,4.0,15.0,30.0,"IL12A,IL12B,KIR3DL2,MICB",0.2030624371067021,0.20466257324048648]
["PR6","IPA","Antiproliferative Role of Somatostatin Receptor 2","Antiproliferative Role of Somatostatin Receptor 2",3.2312533560764867,0.27015866349459544,5.0,78.0,11.0,"MAPK1,MAPK3,SRC,PTPN6,PTPN11",0.2030624371067021,0.20466257324048648]
["PR6","IPA","Molecular Mechanisms of Cancer","Molecular Mechanisms of Cancer",3.216375371760732,0.2713512998284493,13.0,78.0,67.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,PTPN11,PRKACA,CRK,FYN,CAMK2A,CAMK2B,CAMK2D,PA2G4",0.20695551286529715,0.20848604462747936]
["PR17","IPA","Acute Phase Response Signaling","Acute Phase Response Signaling",3.188482431313143,0.28108373737790926,5.0,12.0,71.0,"APCS,C4A,C5,CRP,ITIH4",0.2157135309535009,0.21710928333754168]
["TR24","IPA","CCR5 Signaling in Macrophages","CCR5 Signaling in Macrophages",3.185410006463611,0.144264966414454,5.0,108.0,66.0,"GNAZ,GNG7,GNG11,TRB,CALM3",0.2157135309535009,0.21710928333754168]
["TR24","IPA","Androgen Signaling","Androgen Signaling",3.1596175933063013,0.1485895662579645,6.0,108.0,101.0,"GNAZ,GNG7,GNG11,PRKAR2B,CALM3,TGFB1I1",0.22559507946042978,0.22695509653796517]
["TR22","IPA","ILK Signaling","ILK Signaling",3.139347173992931,0.15124102324113142,32.0,1644.0,113.0,"ATM,PIK3C2A,PIK3CA,MAPK8,VIM,PPP1R12A,PPP2R5A,PPP2R5C,NFKB1,NFKB2,REL,PDPK1,ACTA2,FLNA,FN1,ITGB8,MYH9,MYL5,PTK2,TMSB4Y,PDGFC,RHOB,FNBP1,RHOF,RHOT1,CASP3,VEGFA,VEGFB,CTNNB1,ILK,RSU1,TESK1",0.23299740970810257,0.23430213667266017]
["TR31","IPA","iNOS Signaling","iNOS Signaling",3.1079185708375276,0.1562841132817492,5.0,229.0,33.0,"CHUK,IKBKE,CALM1,IFNGR1,IRAK3",0.2464190998193583,0.24749983117288415]
["PR52","IPA","Extrinsic Prothrombin Activation Pathway","Extrinsic Prothrombin Activation Pathway",3.100915527268319,0.33432447173183777,2.0,5.0,10.0,"F10,PROS1",0.2464190998193583,0.24749983117288415]
["TR24","IPA","FAK Signaling","FAK Signaling",3.0967990800346836,0.1562841132817492,5.0,108.0,69.0,"EGF,ITGA2B,ITGB3,ITGB5,VCL",0.2464190998193583,0.24749983117288415]
["TR24","IPA","Antiproliferative Role of Somatostatin Receptor 2","Antiproliferative Role of Somatostatin Receptor 2",3.08938639569228,0.1562841132817492,4.0,108.0,40.0,"GNG7,GNG11,GUCY1A3,GUCY1B3",0.2472738504063712,0.24826382578611195]
["TR11","h.all.v5.0.entrez","HALLMARK_INFLAMMATORY_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INFLAMMATORY_RESPONSE",3.0649593069013092,0.10957311595964571,23.0,787.0,147.0,"CD69,IL7R,TLR2,MXD1,IL1R1,IFNAR1,CSF3R,EBI3,PSEN1,RASGRP1,FPR1,LCK,RAF1,ATP2A2,AQP9,PTAFR,TLR1,SCARF1,BEST1,SLAMF1,SLC31A2,RNF144B,C5AR1",0.2742839857836002,0.3869593320562059]
["TR31","h.all.v5.0.entrez","HALLMARK_ADIPOGENESIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ADIPOGENESIS",3.0621829808988745,0.10957311595964571,10.0,229.0,134.0,"CCNG2,IFNGR1,CHCHD10,ACO2,NABP1,CD302,UQCRC1,CHUK,PPP1R15B,UCP2",0.2742839857836002,0.3869593320562059]
["TR24","IPA","Gαi Signaling","Gαi Signaling",3.04016954353209,0.16695461858203348,5.0,108.0,71.0,"GNAZ,GNG7,GNG11,PRKAR2B,TBXA2R",0.27074242740969184,0.2716278022805132]
["TR22","IPA","Hepatic Fibrosis / Hepatic Stellate Cell Activation","Hepatic Fibrosis / Hepatic Stellate Cell Activation",3.038426396244734,0.16695461858203348,24.0,1644.0,78.0,"NFKB1,NFKB2,REL,ACTA2,FN1,MYH9,MYL5,PDGFC,CD40,IL4,IL8,FAS,CD40LG,TGFB1,VEGFA,VEGFB,SMAD2,SMAD4,TGFBR1,LEPR,HGF,IL18RAP,LY96,IGFBP4",0.27074242740969184,0.2716278022805132]
["TR18","h.all.v5.0.entrez","HALLMARK_PROTEIN_SECRETION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PROTEIN_SECRETION",3.0317290416745863,0.10957311595964571,29.0,2408.0,71.0,"ATP7A,TPD52,KIF1B,TMED2,LMAN1,COPE,BET1,CLCN3,MON2,ARFGEF2,NAPG,TMX1,VAMP4,NAPA,GNAS,STX16,YKT6,SNX2,CLN5,SGMS1,USO1,ANP32E,AP2B1,GBF1,BNIP3,GOLGA4,AP1G1,STAM,ARFGAP3",0.2742839857836002,0.3869593320562059]
["TR16","h.all.v5.0.entrez","HALLMARK_OXIDATIVE_PHOSPHORYLATION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_OXIDATIVE_PHOSPHORYLATION",3.0151178882166345,0.10957311595964571,28.0,1114.0,139.0,"POLR2F,COX17,CASP7,NDUFAB1,UQCR10,MGST3,ATP5O,NDUFS3,NDUFB7,COX6C,FDX1,PHB2,MDH1,UQCRH,NDUFA1,CYCS,NDUFA6,NDUFV2,ATP5H,ATP5J2,ETFA,ABCB7,NDUFB2,MFN2,COX11,MRPL11,MRPL34,MRPL35",0.2742839857836002,0.3869593320562059]
["PR17","IPA","Complement System","Complement System",3.0100367016710994,0.40100313633279866,3.0,12.0,19.0,"C4A,C5,CFI",0.28378435087490367,0.2845152058710696]
["TR22","IPA","Actin Cytoskeleton Signaling","Actin Cytoskeleton Signaling",3.006713261344645,0.17522162645462325,35.0,1644.0,129.0,"ATM,KRAS,PIK3C2A,PIK3CA,MRAS,PPP1R12A,PPP1CB,PIP4K2B,PIP5K1C,PIKFYVE,ACTA2,CSK,DIAPH1,FLNA,FN1,ITGA2,ITGB8,KNG1,MSN,MYH9,MYL5,PFN2,PTK2,RDX,ROCK1,TRIO,ITGA10,TMSB4Y,ROCK2,ACTR2,APC2,VAV3,IQGAP2,GIT1,PDGFC",0.28378435087490367,0.2845152058710696]
["PR6","IPA","mTOR Signaling","mTOR Signaling",2.959959137962908,0.4373825807860166,8.0,78.0,31.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PDPK1,RPS6KA3,EIF4G2,RPS27A",0.3103371621474623,0.31093184053099154]
["TR20","IPA","B Cell Receptor Signaling","B Cell Receptor Signaling",2.956872535461045,0.19185052830265079,5.0,69.0,116.0,"KRAS,PIK3CB,INPP5B,PPP3R1,REL",0.3103371621474623,0.31093184053099154]
["PR6","IPA","EIF2 Signaling","EIF2 Signaling",2.949460105237938,0.4373825807860166,6.0,78.0,18.0,"MAPK1,MAPK3,PDPK1,EIF4G2,EIF5,RPS27A",0.3117821035029698,0.3122806964429381]
["TR1","IPA","TREM1 Signaling","TREM1 Signaling",2.9422233926679406,0.19381749538125884,6.0,271.0,45.0,"AKT3,REL,JAK2,MYD88,TLR7,FCGR2B",0.3131547920266034,0.19799703932405646]
["TR24","IPA","P2Y Purigenic Receptor Signaling Pathway","P2Y Purigenic Receptor Signaling Pathway",2.9063581556415556,0.19407965334792113,5.0,108.0,76.0,"GNG7,GNG11,PRKAR2B,ITGA2B,ITGB3",0.32680665822189836,0.3307861244541592]
["TR24","IPA","ILK Signaling","ILK Signaling",2.904412278552664,0.19407965334792113,6.0,108.0,113.0,"ITGB3,ITGB5,NCK2,TGFB1I1,LIMS1,PARVB",0.32680665822189836,0.3307861244541592]
["TR22","IPA","RhoGDI Signaling","RhoGDI Signaling",2.9034887913735146,0.19407965334792113,30.0,1644.0,107.0,"PRKCA,MRAS,PPP1R12A,PIP4K2B,PIP5K1C,PIKFYVE,GNAI3,GNB1,GNG3,GNG2,GNB4,ACTA2,ITGA2,ITGB8,MSN,MYL5,RDX,ROCK1,ITGA10,ROCK2,ACTR2,RHOB,FNBP1,RHOF,RHOT1,ARHGEF10,ARHGAP1,ARHGAP4,ARHGAP12,ARHGDIA",0.32680665822189836,0.3307861244541592]
["TR14","IPA","Role of NFAT in Regulation of the Immune Response","Role of NFAT in Regulation of the Immune Response",2.90300695956917,0.19407965334792113,7.0,120.0,139.0,"HLA-DOA,HLA-DOB,IGH,IGL,CD79A,CD79B,BLNK",0.32680665822189836,0.3307861244541592]
["PR6","IPA","Fc Epsilon RI Signaling","Fc Epsilon RI Signaling",2.896990136795484,0.48121157688799093,9.0,78.0,39.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PTPN11,PDPK1,FYN,BTK,LYN",0.32755702458855784,0.3314079428364533]
["PR36","h.all.v5.0.entrez","HALLMARK_SPERMATOGENESIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_SPERMATOGENESIS",2.878629235903799,0.7125858641292567,2.0,7.0,9.0,"AURKA,POMC",0.3256082719238325,0.39985965589637157]
["TR22","h.all.v5.0.entrez","HALLMARK_PROTEIN_SECRETION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PROTEIN_SECRETION",2.876635478251113,0.13759906251672546,22.0,1644.0,71.0,"PAM,SEC24D,RPS6KA3,ARCN1,RAB14,AP3S1,CLCN3,AP2S1,ICA1,SCAMP1,RAB2A,VPS4B,STX7,SGMS1,SCRN1,SEC31A,VAMP7,RAB22A,GALC,ADAM10,AP1G1,RAB9A",0.3256082719238325,0.39985965589637157]
["PR6","IPA","CXCR4 Signaling","CXCR4 Signaling",2.865861957316458,0.48616832705484403,7.0,78.0,25.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,CRK,LYN",0.340659747385493,0.34399701149479145]
["PR6","IPA","Role of NFAT in Regulation of the Immune Response","Role of NFAT in Regulation of the Immune Response",2.865861957316458,0.48616832705484403,7.0,78.0,25.0,"PRKCQ,MAPK1,MAPK3,FYN,BTK,LYN,KPNB1",0.340659747385493,0.34399701149479145]
["PR6","IPA","ERK/MAPK Signaling","ERK/MAPK Signaling",2.8611310775371734,0.48616832705484403,8.0,78.0,32.0,"PRKCB,MAPK1,MAPK3,SRC,YWHAB,PRKACA,CRK,FYN",0.340659747385493,0.34399701149479145]
["TR24","IPA","Caveolar-mediated Endocytosis Signaling","Caveolar-mediated Endocytosis Signaling",2.8587548702596037,0.2074495129267458,4.0,108.0,46.0,"EGF,ITGA2B,ITGB3,ITGB5",0.340659747385493,0.34399701149479145]
["TR24","IPA","Tight Junction Signaling","Tight Junction Signaling",2.8556876595178875,0.2074495129267458,5.0,108.0,78.0,"PRKAR2B,MYLK,VCL,CLDN5,JAM3",0.340659747385493,0.34399701149479145]
["TR22","IPA","Colorectal Cancer Metastasis Signaling","Colorectal Cancer Metastasis Signaling",2.846061266081022,0.2074495129267458,38.0,1644.0,146.0,"ATM,BAD,KRAS,PIK3C2A,PIK3CA,MAPK8,MRAS,NFKB1,NFKB2,REL,GNAI3,GNB1,GNG3,PRKAG1,PRKAR1B,GNG2,GNB4,PDGFC,RHOB,FNBP1,RHOF,RHOT1,TGFB1,CASP3,VEGFA,VEGFB,SMAD2,SMAD4,TGFBR1,FZD2,FZD3,FZD6,FZD8,CTNNB1,AXIN1,ARRB1,PTGER4,MSH3",0.3445498714854135,0.3477991852200624]
["TR22","IPA","Germ Cell-Sertoli Cell Junction Signaling","Germ Cell-Sertoli Cell Junction Signaling",2.838602229741572,0.2074495129267458,27.0,1644.0,94.0,"ATM,KRAS,PIK3C2A,PIK3CA,MAPK8,MRAS,TUBB6,PDPK1,ACTA2,ITGA2,PTK2,RHOB,FNBP1,RHOF,RHOT1,MAP2K7,MAP3K1,TGFB1,TGFBR1,MAP3K8,MAP3K9,CTNNB1,AXIN1,ILK,EPN2,AGGF1,RAB8B",0.3467897267815876,0.3499360729007589]
["TR2","IPA","Lymphotoxin β Receptor Signaling","Lymphotoxin β Receptor Signaling",2.828372488384681,0.20830946009659493,3.0,61.0,38.0,"MAPK1,TRAF1,LTB",0.35131784752209666,0.35438229803332333]
["TR13","h.all.v5.0.entrez","HALLMARK_ALLOGRAFT_REJECTION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ALLOGRAFT_REJECTION",2.812109457134441,0.13759906251672546,9.0,172.0,160.0,"CCL4,CCL5,PRF1,IL2RB,STAT4,GZMB,CD247,ZAP70,KLRD1",0.3256082719238325,0.39985965589637157]
["TR4","h.all.v5.0.entrez","HALLMARK_WNT_BETA_CATENIN_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_WNT_BETA_CATENIN_SIGNALING",2.811471074672744,0.13759906251672546,3.0,76.0,31.0,"RBPJ,NOTCH4,CUL1",0.3256082719238325,0.39985965589637157]
["PR6","IPA","Gαq Signaling","Gαq Signaling",2.810348791964557,0.5340534520497245,6.0,78.0,19.0,"PRKCB,PRKCQ,MAPK1,MAPK3,CSK,BTK",0.36239006416528335,0.36542696861759266]
["TR11","IPA","Toll-like Receptor Signaling","Toll-like Receptor Signaling",2.80014799694673,0.21810265822552527,10.0,787.0,44.0,"FOS,MAP2K4,TRAF6,TLR1,TLR2,TLR4,TLR6,TLR8,IRAK4,SIGIRR",0.3671779355390608,0.3701318732729159]
["TR24","IPA","Ephrin B Signaling","Ephrin B Signaling",2.789378573248342,0.21943833139863925,4.0,108.0,48.0,"GNAZ,GNG7,GNG11,NCK2",0.3725560822416478,0.3754310233520348]
["PR8","IPA","eNOS Signaling","eNOS Signaling",2.7802516724851642,0.5528735563851043,3.0,15.0,18.0,"PRKAA1,HSPA8,VEGFA",0.3766252559426133,0.37941057394975114]
["PR23","IPA","Communication between Innate and Adaptive Immune Cells","Communication between Innate and Adaptive Immune Cells",2.7693746936151613,0.5528735563851043,3.0,10.0,31.0,"IL6,TLR2,IL3",0.37887621786438724,0.3813276977599834]
["PR6","IPA","RAR Activation","RAR Activation",2.7666625187599854,0.5528735563851043,8.0,78.0,33.0,"PRKCB,PRKCQ,MAPK1,SRC,PDPK1,PRKACA,CSK,CSNK2A1",0.37887621786438724,0.3813276977599834]
["TR4","h.all.v5.0.entrez","HALLMARK_PEROXISOME","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PEROXISOME",2.766026312174201,0.14259260860434272,4.0,76.0,69.0,"IDH2,DHCR24,ABCC5,GSTK1",0.3256082719238325,0.39985965589637157]
["TR22","IPA","Thrombin Signaling","Thrombin Signaling",2.764698789755645,0.22804646580793755,30.0,1644.0,109.0,"ATM,KRAS,PIK3C2A,PIK3CA,PRKCA,PLCH2,MRAS,PLCB1,PRKD3,PPP1R12A,PPP1CB,NFKB1,NFKB2,REL,PDPK1,GNAI3,GNB1,GNG3,GNG2,GNB4,MYL5,PTK2,ROCK1,ROCK2,RHOB,FNBP1,RHOF,RHOT1,ITPR2,ARHGEF10",0.37887621786438724,0.3813276977599834]
["PR2","h.all.v5.0.entrez","HALLMARK_WNT_BETA_CATENIN_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_WNT_BETA_CATENIN_SIGNALING",2.7628958167442836,0.7125858641292567,2.0,12.0,6.0,"DKK4,DKK1",0.3256082719238325,0.39985965589637157]
["PR31","IPA","PXR/RXR Activation","PXR/RXR Activation",2.7556154466893963,0.555302349537722,2.0,9.0,8.0,"TNF,INS",0.3831277732597828,0.3854933486569562]
["TR24","IPA","Cardiac β-adrenergic Signaling","Cardiac β-adrenergic Signaling",2.7354213997118384,0.23480804597200436,5.0,108.0,83.0,"GNAZ,GNG7,GNG11,PRKAR2B,PDE5A",0.3975040591796717,0.39984305984501134]
["TR1","h.all.v5.0.entrez","HALLMARK_INFLAMMATORY_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INFLAMMATORY_RESPONSE",2.7294727157977796,0.14365361655974124,11.0,271.0,147.0,"RIPK2,CCRL2,TNFSF10,IRF7,IFITM1,EIF2AK2,BST2,RTP4,LY6E,LAMP3,AXL",0.3256082719238325,0.03206680797413357]
["TR24","IPA","Actin Nucleation by ARP-WASP Complex","Actin Nucleation by ARP-WASP Complex",2.7232202910377405,0.23480804597200436,4.0,108.0,50.0,"ITGA2B,ITGB3,ITGB5,NCK2",0.398926319291058,0.4009397887714656]
["TR24","IPA","Macropinocytosis Signaling","Macropinocytosis Signaling",2.7232202910377405,0.23480804597200436,4.0,108.0,50.0,"EGF,ITGB3,ITGB5,PDGFA",0.398926319291058,0.4009397887714656]
["TR11","IPA","TREM1 Signaling","TREM1 Signaling",2.721519839239888,0.23480804597200436,10.0,787.0,45.0,"ITGAX,STAT5B,TLR1,TLR2,TLR4,TLR6,TLR8,SIGIRR,LAT2,TREM1",0.398926319291058,0.4009397887714656]
["PR16","IPA","RhoA Signaling","RhoA Signaling",2.709611471433374,0.6047538524529701,4.0,98.0,7.0,"CFL1,IGF1,EPHA1,ABL2",0.40621979249233847,0.40816105637105116]
["PR43","h.all.v5.0.entrez","HALLMARK_KRAS_SIGNALING_UP","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_KRAS_SIGNALING_UP",2.708676859440583,0.7125858641292567,3.0,7.0,43.0,"CFB,CFH,NGF",0.3256082719238325,0.39985965589637157]
["TR14","IPA","p70S6K Signaling","p70S6K Signaling",2.7034905763872312,0.24068166019781773,5.0,120.0,76.0,"IGH,IGL,CD79A,CD79B,CD19",0.40820585777152796,0.4100491293712819]
["TR16","h.all.v5.0.entrez","HALLMARK_E2F_TARGETS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_E2F_TARGETS",2.6954871156217814,0.14365361655974124,26.0,1114.0,132.0,"RACGAP1,BIRC5,TOP2A,DLGAP5,AURKA,CCNB2,RFC3,NME1,POLE4,CHEK1,CDKN2C,HN1,EIF2S1,TFRC,RRM2,EED,MELK,TIPIN,RAN,KIF18B,RAD51C,CBX5,EXOSC8,NUP107,PRDX4,CDKN2A",0.3256082719238325,0.39985965589637157]
["TR18","IPA","Regulation of eIF4 and p70S6K Signaling","Regulation of eIF4 and p70S6K Signaling",2.691038940183585,0.2436217452896904,38.0,2408.0,104.0,"ATM,NRAS,PIK3C3,PIK3CG,MAP2K2,RRAS2,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R5D,PPM1L,RPS6KB1,PDPK1,ITGAE,ITGAV,ITGB2,SOS1,EIF4E,EIF4A2,FAU,EIF3E,RPS2,RPS7,RPS9,RPS14,RPS15A,RPS17,RPS18,RPS21,RPS23,RPS24,RPS25,RPS27A,RPS29,EIF3J,EIF2S2,PAIP1,EIF2A",0.4162600015959511,0.4180320866128894]
["TR25","h.all.v5.0.entrez","HALLMARK_UNFOLDED_PROTEIN_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UNFOLDED_PROTEIN_RESPONSE",2.6836255161722304,0.14365361655974124,11.0,505.0,81.0,"NOLC1,XBP1,EDEM1,LSM4,SDAD1,IARS,ALDH18A1,HSPA9,BAG3,IMP3,EXOC2",0.3256082719238325,0.39985965589637157]
["PR6","IPA","Glioma Signaling","Glioma Signaling",2.676256635603123,0.636064587931239,8.0,78.0,34.0,"PRKCB,PRKCQ,MAPK1,MAPK3,CAMK2A,CAMK2B,CAMK2D,PA2G4",0.426792415013516,0.42850110350778725]
["PR33","h.all.v5.0.entrez","HALLMARK_XENOBIOTIC_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_XENOBIOTIC_METABOLISM",2.6743550212394704,0.7125858641292567,3.0,8.0,38.0,"ENTPD5,CCL25,MBL2",0.3256082719238325,0.39985965589637157]
["PR6","IPA","α-Adrenergic Signaling","α-Adrenergic Signaling",2.670314801516213,0.636064587931239,5.0,78.0,14.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PRKACA",0.4288085959676818,0.4304186057145322]
["PR52","h.all.v5.0.entrez","HALLMARK_COAGULATION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_COAGULATION",2.6540881388065873,0.7125858641292567,3.0,5.0,67.0,"F10,PROS1,F9",0.3275167719510602,0.39985965589637157]
["PR50","IPA","Role of IL-17A in Psoriasis","Role of IL-17A in Psoriasis",2.648396209662817,0.6437453660403977,2.0,9.0,9.0,"CXCL1,CXCL5",0.43398752648000516,0.4359273595345294]
["PR31","IPA","TNFR1 Signaling","TNFR1 Signaling",2.648396209662817,0.6437453660403977,2.0,9.0,9.0,"TNF,PAK7",0.43398752648000516,0.4359273595345294]
["TR24","IPA","IL-8 Signaling","IL-8 Signaling",2.645246711072255,0.25535342740762595,6.0,108.0,127.0,"GNAZ,GNG7,GNG11,EGF,ITGB3,ITGB5",0.43398752648000516,0.4359273595345294]
["TR20","IPA","PTEN Signaling","PTEN Signaling",2.644636998706303,0.25535342740762595,4.0,69.0,82.0,"KRAS,PIK3CB,INPP5B,REL",0.43398752648000516,0.4359273595345294]
["TR20","IPA","fMLP Signaling in Neutrophils","fMLP Signaling in Neutrophils",2.644636998706303,0.25535342740762595,4.0,69.0,82.0,"KRAS,PIK3CB,PPP3R1,REL",0.43398752648000516,0.4359273595345294]
["TR20","IPA","Estrogen-Dependent Breast Cancer Signaling","Estrogen-Dependent Breast Cancer Signaling",2.6415203684989916,0.25535342740762595,3.0,69.0,39.0,"KRAS,PIK3CB,REL",0.43398752648000516,0.4359273595345294]
["TR1","IPA","Acute Phase Response Signaling","Acute Phase Response Signaling",2.636153806025984,0.25535342740762595,8.0,271.0,88.0,"AKT3,REL,SERPING1,C1QA,IL1RN,JAK2,MYD88,SOCS1",0.43398752648000516,0.3004619948232062]
["PR51","IPA","Hepatic Fibrosis / Hepatic Stellate Cell Activation","Hepatic Fibrosis / Hepatic Stellate Cell Activation",2.6351378134999117,0.6514103007189007,3.0,5.0,68.0,"TIMP2,IGFBP3,IGFBP5",0.43398752648000516,0.4385675887302543]
["TR20","IPA","T Cell Receptor Signaling","T Cell Receptor Signaling",2.6253843095822327,0.25535342740762595,4.0,69.0,83.0,"KRAS,PIK3CB,PPP3R1,REL",0.43853297480810643,0.4429106337339006]
["TR24","IPA","Endothelin-1 Signaling","Endothelin-1 Signaling",2.6234342211911974,0.25535342740762595,5.0,108.0,88.0,"GNAZ,PLA2G12A,GUCY1A3,GUCY1B3,PTGS1",0.43853297480810643,0.4429106337339006]
["TR20","IPA","Angiopoietin Signaling","Angiopoietin Signaling",2.609758659553123,0.25567531031784957,3.0,69.0,40.0,"KRAS,PIK3CB,REL",0.4453337191860689,0.4495334855769696]
["TR20","IPA","Role of NFAT in Regulation of the Immune Response","Role of NFAT in Regulation of the Immune Response",2.6096890420268073,0.25567531031784957,5.0,69.0,139.0,"KRAS,PIK3CB,PPP3R1,REL,CSNK1G1",0.4453337191860689,0.4495334855769696]
["TR15","IPA","Cdc42 Signaling","Cdc42 Signaling",2.6017719767462033,0.25567531031784957,3.0,30.0,93.0,"SRC,HLA-DMB,HLA-DRA",0.4498982637559639,0.45402000456241026]
["TR14","IPA","Systemic Lupus Erythematosus Signaling","Systemic Lupus Erythematosus Signaling",2.5939666326767283,0.25567531031784957,6.0,120.0,117.0,"CD40,IGH,IGL,CD79A,CD79B,CD72",0.45281354818949837,0.45672422851628036]
["TR22","IPA","Factors Promoting Cardiogenesis in Vertebrates","Factors Promoting Cardiogenesis in Vertebrates",2.5920731734677536,0.25567531031784957,16.0,1644.0,48.0,"PRKCA,PRKD3,CDK2,APC2,TGFB1,SMAD2,SMAD4,TGFBR1,FZD2,FZD3,FZD6,FZD8,SMAD9,CTNNB1,AXIN1,CDC6",0.45281354818949837,0.45672422851628036]
["TR5","h.all.v5.0.entrez","HALLMARK_INTERFERON_ALPHA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_ALPHA_RESPONSE",2.587282391584188,0.16811896765471587,3.0,31.0,91.0,"CXCL11,ELF1,SAMD9",0.34724499899229405,0.42055394861703776]
["TR31","IPA","IL-1 Signaling","IL-1 Signaling",2.5851669502716237,0.25626314711106896,6.0,229.0,62.0,"CHUK,IKBKE,GNA12,GNA13,GNG10,IRAK3",0.4564775117382445,0.4603028886590219]
["PR35","h.all.v5.0.entrez","HALLMARK_CHOLESTEROL_HOMEOSTASIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_CHOLESTEROL_HOMEOSTASIS",2.5748573429941315,0.7125858641292567,2.0,8.0,11.0,"HMGCR,TNFRSF12A",0.34724499899229405,0.42055394861703776]
["TR11","h.all.v5.0.entrez","HALLMARK_IL6_JAK_STAT3_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_IL6_JAK_STAT3_SIGNALING",2.5574638211542147,0.16811896765471587,13.0,787.0,71.0,"TLR2,IL1R1,CSF2RB,IL13RA1,IL10RB,IL1R2,IFNAR1,TNFRSF1A,CSF3R,CSF2RA,EBI3,IL17RA,CBL",0.34724499899229405,0.42055394861703776]
["PR9","h.all.v5.0.entrez","HALLMARK_COAGULATION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_COAGULATION",2.5525939268859856,0.7125858641292567,6.0,24.0,67.0,"SERPINE1,PDGFB,THBS1,PF4,SPARC,GP1BA",0.34724499899229405,0.42055394861703776]
["TR1","h.all.v5.0.entrez","HALLMARK_TNFA_SIGNALING_VIA_NFKB","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TNFA_SIGNALING_VIA_NFKB",2.548378576083969,0.16811896765471587,11.0,271.0,155.0,"ATF3,TNFAIP3,REL,RIPK2,GADD45B,IFIT2,RNF19B,DDX58,CCRL2,TAP1,IFIH1",0.34724499899229405,0.040547924089799264]
["PR11","h.all.v5.0.entrez","HALLMARK_ANDROGEN_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ANDROGEN_RESPONSE",2.5352639987555654,0.7125858641292567,3.0,30.0,11.0,"LIFR,KLK3,XRCC6",0.34724499899229405,0.42055394861703776]
["PR6","IPA","Role of NFAT in Cardiac Hypertrophy","Role of NFAT in Cardiac Hypertrophy",2.5035151070262676,0.8659810698910421,9.0,78.0,44.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,PRKACA,CAMK2A,CAMK2B,CAMK2D",0.546627516323427,0.5510705670255007]
["TR24","IPA","Gap Junction Signaling","Gap Junction Signaling",2.498666306176494,0.30857252604117846,5.0,108.0,94.0,"TUBB1,PRKAR2B,EGF,GUCY1A3,GUCY1B3",0.5485126506678337,0.5528349415093952]
["PR10","IPA","Apoptosis Signaling","Apoptosis Signaling",2.494210110214353,0.8689365351256708,3.0,13.0,26.0,"PLCG1,CDK1,BCL2",0.5499394829727378,0.55413872945213]
["TR4","IPA","Polyamine Regulation in Colon Cancer","Polyamine Regulation in Colon Cancer",2.4903171894080964,0.31042310858287075,3.0,76.0,40.0,"PSMA5,PSMB2,PSME2",0.5506874590390574,0.5547600475650912]
["PR51","IPA","Growth Hormone Signaling","Growth Hormone Signaling",2.483656349791791,0.8746916680156479,2.0,5.0,20.0,"PRKCA,IGFBP3",0.5549940359304466,0.5589671373214905]
["TR6","h.all.v5.0.entrez","HALLMARK_INTERFERON_GAMMA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_GAMMA_RESPONSE",2.466592716534204,0.19373103023466198,4.0,35.0,183.0,"TNFAIP6,CASP1,TRIM25,CD274",0.3940206630553931,0.47365230801825076]
["TR9","IPA","T Helper Cell Differentiation","T Helper Cell Differentiation",2.4631679598310985,0.3188725534036902,6.0,269.0,56.0,"TNF,HLA-DQA1,TRB,IL12B,IL10RA,IL21R",0.5767856379919044,0.579315272763309]
["PR6","IPA","Chemokine Signaling","Chemokine Signaling",2.458113394606679,0.8872745238939703,7.0,78.0,29.0,"PRKCB,MAPK1,MAPK3,SRC,CAMK2A,CAMK2B,CAMK2D",0.5767856379919044,0.579315272763309]
["PR30","IPA","B Cell Development","B Cell Development",2.454417193691202,0.8872745238939703,2.0,17.0,6.0,"CD80,IGHM",0.5767856379919044,0.579315272763309]
["PR6","IPA","Gap Junction Signaling","Gap Junction Signaling",2.447998348170447,0.8872745238939703,6.0,78.0,22.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,PRKACA",0.5767856379919044,0.579315272763309]
["PR6","IPA","NGF Signaling","NGF Signaling",2.447998348170447,0.8872745238939703,6.0,78.0,22.0,"MAPK1,MAPK3,PTPN11,PDPK1,CRK,RPS6KA3",0.5767856379919044,0.579315272763309]
["TR16","IPA","Systemic Lupus Erythematosus Signaling","Systemic Lupus Erythematosus Signaling",2.4377771095720475,0.3188725534036902,23.0,1114.0,117.0,"ATM,PIK3CD,PLCG2,PIK3R6,SOS1,IL1B,CD3D,CD3G,IGL,TRA,TRB,LYN,CREM,FCGR3B,SNRPB2,SNRPF,TXNL4A,SNRNP27,LSM6,LSM5,LSM7,SNRNP25,ZCRB1",0.5767856379919044,0.579315272763309]
["TR20","IPA","IL-15 Signaling","IL-15 Signaling",2.4358113782024864,0.3188725534036902,3.0,69.0,46.0,"KRAS,PIK3CB,REL",0.5767856379919044,0.579315272763309]
["TR14","IPA","Communication between Innate and Adaptive Immune Cells","Communication between Innate and Adaptive Immune Cells",2.434352585403454,0.3188725534036902,4.0,120.0,54.0,"CD40,IGH,IGL,CD83",0.5767856379919044,0.579315272763309]
["TR15","IPA","Graft-versus-Host Disease Signaling","Graft-versus-Host Disease Signaling",2.43213079423488,0.3188725534036902,2.0,30.0,31.0,"HLA-DMB,HLA-DRA",0.5767856379919044,0.579315272763309]
["TR20","IPA","Gap Junction Signaling","Gap Junction Signaling",2.429569337921641,0.3188725534036902,4.0,69.0,94.0,"KRAS,PIK3CB,PPP3R1,CSNK1G1",0.5767856379919044,0.579315272763309]
["PR18","IPA","Amyloid Processing","Amyloid Processing",2.4264290132335984,0.888745076582855,2.0,9.0,13.0,"MAPK14,CAPN1",0.5767856379919044,0.579315272763309]
["PR19","IPA","Intrinsic Prothrombin Activation Pathway","Intrinsic Prothrombin Activation Pathway",2.4264290132335984,0.888745076582855,2.0,8.0,13.0,"KLKB1,F11",0.5767856379919044,0.579315272763309]
["PR35","IPA","Small Cell Lung Cancer Signaling","Small Cell Lung Cancer Signaling",2.4264290132335984,0.888745076582855,2.0,8.0,13.0,"CDKN1B,PTEN",0.5767856379919044,0.579315272763309]
["TR8","h.all.v5.0.entrez","HALLMARK_INTERFERON_GAMMA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_GAMMA_RESPONSE",2.42148641031705,0.19983400243430588,4.0,36.0,183.0,"CCL2,CDKN1A,GBP4,NOD1",0.42226827895344377,0.49776291223067715]
["PR23","IPA","Dendritic Cell Maturation","Dendritic Cell Maturation",2.4131949531736177,0.9021481965280509,3.0,10.0,41.0,"IL6,TLR2,IL1RL2",0.5786450597767967,0.5794804098597351]
["TR13","IPA","Dopamine-DARPP32 Feedback in cAMP Signaling","Dopamine-DARPP32 Feedback in cAMP Signaling",2.410895578968223,0.3188725534036902,6.0,172.0,89.0,"PRKCH,PPP2R2B,PPP3CC,CACNA2D2,ADCY9,ATP2A2",0.5786450597767967,0.5794804098597351]
["TR11","IPA","IL-8 Signaling","IL-8 Signaling",2.40599838442807,0.3188725534036902,19.0,787.0,127.0,"FOS,PIK3CG,PRKCQ,RAF1,MAP2K4,GNAQ,ITGAM,ITGAX,LIMK2,PAK2,IQGAP1,RHOH,RHOQ,TRAF6,PLD6,CXCR2,IRAK4,NCF2,CXCR1",0.5786450597767967,0.5794804098597351]
["TR14","IPA","IL-4 Signaling","IL-4 Signaling",2.405471299728508,0.3188725534036902,4.0,120.0,55.0,"HLA-DOA,HLA-DOB,IGH,FCER2",0.5786450597767967,0.5794804098597351]
["TR15","IPA","Autoimmune Thyroid Disease Signaling","Autoimmune Thyroid Disease Signaling",2.404895102867325,0.3188725534036902,2.0,30.0,32.0,"HLA-DMB,HLA-DRA",0.5786450597767967,0.5794804098597351]
["TR10","h.all.v5.0.entrez","HALLMARK_INTERFERON_ALPHA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_ALPHA_RESPONSE",2.40027609235348,0.19983400243430588,3.0,36.0,91.0,"CXCL10,NCOA7,IL15",0.42226827895344377,0.49776291223067715]
["TR27","h.all.v5.0.entrez","HALLMARK_MYC_TARGETS_V2","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MYC_TARGETS_V2",2.3976051898155077,0.19983400243430588,8.0,690.0,39.0,"RRP12,NOP56,PPRC1,TCOF1,UTP20,FARSA,PUS1,IMP4",0.42226827895344377,0.49776291223067715]
["PR3","IPA","iNOS Signaling","iNOS Signaling",2.390932156163628,0.9352120702414433,2.0,12.0,9.0,"MAPK11,LBP",0.5786450597767967,0.5794804098597351]
["TR3","IPA","Mouse Embryonic Stem Cell Pluripotency","Mouse Embryonic Stem Cell Pluripotency",2.3894587998742414,0.3188725534036902,3.0,54.0,61.0,"GSK3B,PIK3CB,TCF3",0.5786450597767967,0.5794804098597351]
["TR22","IPA","CXCR4 Signaling","CXCR4 Signaling",2.386053883045067,0.3188725534036902,25.0,1644.0,91.0,"ATM,KRAS,PIK3C2A,PIK3CA,PRKCA,MAPK8,MRAS,PLCB1,PRKD3,GNAI3,GNB1,GNG3,GNG2,GNB4,MYL5,PTK2,ROCK1,ROCK2,RHOB,FNBP1,RHOF,RHOT1,ITPR2,EGR1,ELMO2",0.5786450597767967,0.5794804098597351]
["TR15","IPA","Leukocyte Extravasation Signaling","Leukocyte Extravasation Signaling",2.3844106590276146,0.3188725534036902,3.0,30.0,111.0,"SRC,CTNND1,CYBB",0.5786450597767967,0.5794804098597351]
["TR20","IPA","Erythropoietin Signaling","Erythropoietin Signaling",2.3833221338255033,0.3188725534036902,3.0,69.0,48.0,"KRAS,PIK3CB,REL",0.5786450597767967,0.5794804098597351]
["TR20","IPA","GM-CSF Signaling","GM-CSF Signaling",2.3833221338255033,0.3188725534036902,3.0,69.0,48.0,"KRAS,PIK3CB,PPP3R1",0.5786450597767967,0.5794804098597351]
["TR20","IPA","PEDF Signaling","PEDF Signaling",2.3833221338255033,0.3188725534036902,3.0,69.0,48.0,"KRAS,PIK3CB,REL",0.5786450597767967,0.5794804098597351]
["TR24","IPA","IL-1 Signaling","IL-1 Signaling",2.381135767085301,0.3188725534036902,4.0,108.0,62.0,"GNAZ,GNG7,GNG11,PRKAR2B",0.5786450597767967,0.5794804098597351]
["TR20","IPA","PI3K/AKT Signaling","PI3K/AKT Signaling",2.3806960026994815,0.3188725534036902,4.0,69.0,97.0,"KRAS,PIK3CB,INPP5B,REL",0.5786450597767967,0.5794804098597351]
["TR20","IPA","PKCθ Signaling in T Lymphocytes","PKCθ Signaling in T Lymphocytes",2.3806960026994815,0.3188725534036902,4.0,69.0,97.0,"KRAS,PIK3CB,PPP3R1,REL",0.5786450597767967,0.5794804098597351]
["PR35","IPA","Bladder Cancer Signaling","Bladder Cancer Signaling",2.37832977467437,0.9443338435515871,3.0,8.0,48.0,"FGF2,PGF,MMP3",0.5786450597767967,0.5794804098597351]
["TR14","IPA","T Helper Cell Differentiation","T Helper Cell Differentiation",2.3771964528381013,0.3188725534036902,4.0,120.0,56.0,"CD40,HLA-DOA,HLA-DOB,CXCR5",0.5786450597767967,0.5794804098597351]
["PR48","IPA","Antiproliferative Role of TOB in T Cell Signaling","Antiproliferative Role of TOB in T Cell Signaling",2.373751727929282,0.9443338435515871,2.0,11.0,10.0,"CDK2,TGFB1",0.5796965702852719,0.5804443994907111]
["PR14","h.all.v5.0.entrez","HALLMARK_ESTROGEN_RESPONSE_EARLY","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ESTROGEN_RESPONSE_EARLY",2.371109816449577,0.9014351078072985,6.0,113.0,16.0,"IL6ST,CXCL12,TFF3,GFRA1,IGF1R,NBL1",0.43002391481064844,0.49875843884305204]
["TR17","h.all.v5.0.entrez","HALLMARK_HYPOXIA","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HYPOXIA",2.3563558310161774,0.21129314447860892,14.0,531.0,122.0,"JUN,MXI1,SLC2A1,BNIP3L,CITED2,PIM1,PRDX5,SCARB1,FOXO3,SIAH2,NEDD4L,TGM2,HOXB9,SELENBP1",0.43002391481064844,0.49875843884305204]
["TR24","IPA","Gαs Signaling","Gαs Signaling",2.356151456739314,0.3302624139349951,4.0,108.0,63.0,"GNAZ,GNG7,GNG11,PRKAR2B",0.6000133397976224,0.6006963637581798]
["PR2","h.all.v5.0.entrez","HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION",2.3539854871772543,0.9014351078072985,4.0,12.0,65.0,"CXCL6,DKK1,TIMP3,MMP1",0.43002391481064844,0.49875843884305204]
["TR15","IPA","Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells","Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells",2.352999598732242,0.3302624139349951,2.0,30.0,34.0,"HLA-DMB,HLA-DRA",0.6007428632253947,0.6013367173804218]
["PR6","IPA","T Cell Receptor Signaling","T Cell Receptor Signaling",2.34233997297492,1.0,6.0,78.0,23.0,"PRKCQ,MAPK1,MAPK3,CSK,FYN,BTK",0.6119837109582875,0.6124981177192398]
["TR20","IPA","IL-3 Signaling","IL-3 Signaling",2.3331941256123008,0.3421806958268346,3.0,69.0,50.0,"KRAS,PIK3CB,PPP3R1",0.6212879057805134,0.6217193182660826]
["TR1","h.all.v5.0.entrez","HALLMARK_COMPLEMENT","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_COMPLEMENT",2.317318225739493,0.22260381111259145,10.0,271.0,143.0,"TNFAIP3,PLSCR1,ME1,GPD2,JAK2,IRF7,PSMB9,LAP3,SERPING1,C1QA",0.45590972852867295,0.05916735913500887]
["TR20","IPA","LPS-stimulated MAPK Signaling","LPS-stimulated MAPK Signaling",2.3089555248131965,0.3515932445673064,3.0,69.0,51.0,"KRAS,PIK3CB,REL",0.6487252191396079,0.6515981883990987]
["TR24","IPA","G Beta Gamma Signaling","G Beta Gamma Signaling",2.307544379543775,0.3515932445673064,4.0,108.0,65.0,"GNAZ,GNG7,GNG11,PRKAR2B",0.6487252191396079,0.6515981883990987]
["TR1","IPA","IL-12 Signaling and Production in Macrophages","IL-12 Signaling and Production in Macrophages",2.3057700013830957,0.3515932445673064,7.0,271.0,79.0,"PRKCE,AKT3,REL,STAT1,MYD88,APOL1,IL12RB2",0.6487252191396079,0.44943164647875583]
["TR15","IPA","Allograft Rejection Signaling","Allograft Rejection Signaling",2.3042070785687625,0.3515932445673064,2.0,30.0,36.0,"HLA-DMB,HLA-DRA",0.6487252191396079,0.6526927461047467]
["TR13","IPA","CCR5 Signaling in Macrophages","CCR5 Signaling in Macrophages",2.297316486489388,0.3537814027049787,5.0,172.0,66.0,"PRKCH,CD247,CACNA2D2,CCL4,CCL5",0.6523433990411354,0.6561072620691475]
["PR3","IPA","Toll-like Receptor Signaling","Toll-like Receptor Signaling",2.296770786427804,1.0,2.0,12.0,10.0,"MAPK11,LBP",0.6523433990411354,0.6561072620691475]
["TR4","IPA","Role of JAK1 and JAK3 in γc Cytokine Signaling","Role of JAK1 and JAK3 in γc Cytokine Signaling",2.291352329731322,0.3552574519318417,3.0,76.0,47.0,"MAPK1,IRS2,IL15RA",0.6527503743431179,0.6561875375118327]
["PR48","IPA","Cell Cycle: G1/S Checkpoint Regulation","Cell Cycle: G1/S Checkpoint Regulation",2.2890759109784136,1.0,2.0,11.0,11.0,"CDK2,TGFB1",0.6527503743431179,0.6561875375118327]
["PR48","IPA","Cyclins and Cell Cycle Regulation","Cyclins and Cell Cycle Regulation",2.2890759109784136,1.0,2.0,11.0,11.0,"CDK2,TGFB1",0.6527503743431179,0.6561875375118327]
["TR24","IPA","eNOS Signaling","eNOS Signaling",2.283893068372575,0.35800236173250677,4.0,108.0,66.0,"PRKAR2B,CALM3,GUCY1A3,GUCY1B3",0.6540171749964597,0.6572475334813791]
["PR6","IPA","IGF-1 Signaling","IGF-1 Signaling",2.2833541225343787,1.0,7.0,78.0,31.0,"MAPK1,MAPK3,YWHAB,PTPN11,PDPK1,PRKACA,CSNK2A1",0.6540171749964597,0.6572475334813791]
["TR16","h.all.v5.0.entrez","HALLMARK_DNA_REPAIR","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_DNA_REPAIR",2.277097837076158,0.22824028042176148,20.0,1114.0,100.0,"POLR2H,POLR2F,POLR2D,ELL,SNAPC5,RFC3,GTF2A2,NME1,POLE4,RFC4,RFC5,CANT1,NME3,NT5C,UPF3B,TYMS,TK2,BOLA2,MRPL40,COX17",0.4830637785058556,0.5523646598711883]
["PR4","IPA","Inhibition of Matrix Metalloproteases","Inhibition of Matrix Metalloproteases",2.2739471053872116,1.0,4.0,47.0,17.0,"MMP13,MMP10,MMP12,MMP16",0.660953073806,0.6640068544871038]
["PR4","IPA","Sphingosine-1-phosphate Signaling","Sphingosine-1-phosphate Signaling",2.2739471053872116,1.0,4.0,47.0,17.0,"PDIA3,PTK2,CASP3,CASP10",0.660953073806,0.6640068544871038]
["TR20","IPA","NF-κB Activation by Viruses","NF-κB Activation by Viruses",2.26202135601348,0.3728070464392892,3.0,69.0,53.0,"KRAS,PIK3CB,REL",0.6756216577783316,0.6786372801123443]
["TR15","IPA","OX40 Signaling Pathway","OX40 Signaling Pathway",2.2581769574583883,0.3728070464392892,2.0,30.0,38.0,"HLA-DMB,HLA-DRA",0.6779040986805887,0.6808248138884272]
["TR14","ADAMs","ADAMs","ADAMs",2.249171926269774,0.18029266240144015,3.0,120.0,31.0,"FCER2,PTPRK,CD40",0.31993320006036774,0.78263123912912]
["PR35","IPA","ErbB2-ErbB3 Signaling","ErbB2-ErbB3 Signaling",2.244300527070837,1.0,2.0,8.0,16.0,"CDKN1B,PTEN",0.6869957706293173,0.6895413437108209]
["PR6","IPA","CD28 Signaling in T Helper Cells","CD28 Signaling in T Helper Cells",2.243000636951634,1.0,6.0,78.0,24.0,"PRKCQ,PTPN6,PTPN11,PDPK1,CSK,FYN",0.6869957706293173,0.6895413437108209]
["PR6","IPA","Synaptic Long Term Depression","Synaptic Long Term Depression",2.243000636951634,1.0,6.0,78.0,24.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PRDX6,LYN",0.6869957706293173,0.6895413437108209]
["PR6","IPA","iCOS-iCOSL Signaling in T Helper Cells","iCOS-iCOSL Signaling in T Helper Cells",2.243000636951634,1.0,6.0,78.0,24.0,"PRKCQ,PDPK1,CSK,CAMK2A,CAMK2B,CAMK2D",0.6869957706293173,0.6895413437108209]
["TR25","h.all.v5.0.entrez","HALLMARK_E2F_TARGETS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_E2F_TARGETS",2.241555353390168,0.22824028042176148,14.0,505.0,132.0,"RFC1,LIG1,NOLC1,ILF3,CDK4,NUP205,UNG,RPA1,DNMT1,TK1,GINS3,CTPS1,PAICS,PAN2",0.4830637785058556,0.5523646598711883]
["TR29","h.all.v5.0.entrez","HALLMARK_WNT_BETA_CATENIN_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_WNT_BETA_CATENIN_SIGNALING",2.2391581574102606,0.22824028042176148,3.0,121.0,31.0,"MYC,AXIN2,LEF1",0.4830637785058556,0.5523646598711883]
["TR15","IPA","Remodeling of Epithelial Adherens Junctions","Remodeling of Epithelial Adherens Junctions",2.236106208828438,0.38636401356675376,2.0,30.0,39.0,"SRC,CTNND1",0.6942761537045519,0.6967468873476286]
["TR23","h.all.v5.0.entrez","HALLMARK_HYPOXIA","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HYPOXIA",2.2311455977068833,0.22824028042176148,8.0,227.0,122.0,"ENO2,ALDOC,GPI,ENO1,CITED2,SAP30,BCL2,TGFBI",0.4830637785058556,0.5523646598711883]
["TR24","IPA","Thrombin Signaling","Thrombin Signaling",2.224788329074917,0.38636401356675376,5.0,108.0,109.0,"GNAZ,GNG7,GNG11,EGF,MYLK",0.6979537613401511,0.7032270048091274]
["TR1","IPA","Toll-like Receptor Signaling","Toll-like Receptor Signaling",2.223815117527732,0.38636401356675376,5.0,271.0,44.0,"REL,MYD88,TLR7,TNFAIP3,EIF2AK2",0.6979537613401511,0.44943164647875583]
["PR51","IPA","VEGF Family Ligand-Receptor Interactions","VEGF Family Ligand-Receptor Interactions",2.2229234991423388,1.0,2.0,5.0,27.0,"PRKCA,NRP1",0.6979537613401511,0.7032270048091274]
["TR32","h.all.v5.0.entrez","HALLMARK_BILE_ACID_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_BILE_ACID_METABOLISM",2.2209544240590624,0.22824028042176148,3.0,62.0,61.0,"SLC27A2,ATXN1,PECR",0.4830637785058556,0.5523646598711883]
["TR3","IPA","Huntington's Disease Signaling","Huntington's Disease Signaling",2.219079211620199,0.38636401356675376,4.0,54.0,138.0,"PIK3CB,SGK1,UBE2S,PACSIN1",0.6979537613401511,0.7032270048091274]
["TR31","h.all.v5.0.entrez","HALLMARK_CHOLESTEROL_HOMEOSTASIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_CHOLESTEROL_HOMEOSTASIS",2.218357927577413,0.22824028042176148,5.0,229.0,52.0,"JAG1,HMGCR,SREBF2,TP53INP1,CPEB2",0.4830637785058556,0.5523646598711883]
["TR22","IPA","RhoA Signaling","RhoA Signaling",2.217139395648135,0.38636401356675376,20.0,1644.0,70.0,"PPP1R12A,PPP1CB,PIP4K2B,PIP5K1C,PIKFYVE,ACTA2,MSN,MYL5,PFN2,PTK2,RDX,ROCK1,ROCK2,ACTR2,ARHGAP1,ARHGAP4,ARHGAP12,SEPT7,RHPN2,RHPN1",0.6979537613401511,0.7032270048091274]
["TR20","IPA","IL-4 Signaling","IL-4 Signaling",2.217015092011276,0.38636401356675376,3.0,69.0,55.0,"KRAS,PIK3CB,INPP5B",0.6979537613401511,0.7032270048091274]
["PR27","h.all.v5.0.entrez","HALLMARK_HEME_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HEME_METABOLISM",2.2167624442963563,1.0,3.0,30.0,14.0,"TOP1,CAT,EPOR",0.4830637785058556,0.5523646598711883]
["PR43","IPA","Complement System","Complement System",2.2157152722091022,1.0,2.0,7.0,19.0,"CFB,CFH",0.6979537613401511,0.7032270048091274]
["TR24","IPA","Neuregulin Signaling","Neuregulin Signaling",2.215390316077326,0.38636401356675376,4.0,108.0,69.0,"EGF,ITGA2B,ITGB3,ITGB5",0.6979537613401511,0.7032270048091274]
["PR3","IPA","Acute Phase Response Signaling","Acute Phase Response Signaling",2.2135034286853164,1.0,4.0,12.0,71.0,"MAPK11,LBP,AGT,SAA1",0.6979537613401511,0.7032270048091274]
["PR14","IPA","Notch Signaling","Notch Signaling",2.210668177311887,1.0,4.0,113.0,8.0,"NOTCH1,NOTCH3,JAG1,CNTN1",0.698977086754855,0.7041463456815897]
["TR11","h.all.v5.0.entrez","HALLMARK_KRAS_SIGNALING_UP","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_KRAS_SIGNALING_UP",2.2063433760696554,0.22824028042176148,18.0,787.0,123.0,"PPP1R15A,TRIB1,IL7R,F2RL1,AKAP12,CSF2RA,CBL,SPP1,RABGAP1L,ADAM8,WNT7A,AMMECR1,TLR8,PTBP2,LAT2,FBXO4,AVL9,PTCD2",0.4830637785058556,0.5523646598711883]
["TR31","IPA","Relaxin Signaling","Relaxin Signaling",2.202641068550691,0.38897482967297836,6.0,229.0,74.0,"GNA12,GNA13,GNG10,CREB1,PDE4B,TDP2",0.7019929767883195,0.7063273462357492]
["TR29","IPA","Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis","Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",2.2024152870515503,0.38897482967297836,7.0,121.0,184.0,"PRKCA,SOCS3,MYC,LEF1,TLR5,FZD3,IRAK3",0.7019929767883195,0.7063273462357492]
["PR6","h.all.v5.0.entrez","HALLMARK_PI3K_AKT_MTOR_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PI3K_AKT_MTOR_SIGNALING",2.2020159809047013,1.0,7.0,78.0,32.0,"PTPN11,RPS6KA3,MAPK1,YWHAB,UBE2N,PRKCB,DUSP3",0.4830637785058556,0.5523646598711883]
["TR32","IPA","p38 MAPK Signaling","p38 MAPK Signaling",2.201281318713734,0.38897482967297836,3.0,62.0,62.0,"RPS6KA3,MEF2A,TAB2",0.7019929767883195,0.7063273462357492]
["PR6","IPA","Glycolysis I","Glycolysis I",2.199022705803677,1.0,3.0,78.0,6.0,"GAPDH,PGAM1,TPI1",0.7019929767883195,0.7063273462357492]
["TR20","IPA","Ceramide Signaling","Ceramide Signaling",2.1951904044160697,0.3897313128240673,3.0,69.0,56.0,"KRAS,PIK3CB,REL",0.7019929767883195,0.7063273462357492]
["PR31","IPA","FXR/RXR Activation","FXR/RXR Activation",2.1950666450691756,1.0,2.0,9.0,15.0,"TNF,INS",0.7019929767883195,0.7063273462357492]
["TR24","IPA","Leukocyte Extravasation Signaling","Leukocyte Extravasation Signaling",2.1917769334475516,0.3897313128240673,5.0,108.0,111.0,"VCL,CTTN,ARHGAP6,CLDN5,JAM3",0.7019929767883195,0.7063273462357492]
["PR19","IPA","MSP-RON Signaling Pathway","MSP-RON Signaling Pathway",2.1915963193515346,1.0,2.0,8.0,17.0,"KLKB1,F11",0.7019929767883195,0.7063273462357492]
["TR1","IPA","Type II Diabetes Mellitus Signaling","Type II Diabetes Mellitus Signaling",2.1885773090859924,0.3897313128240673,7.0,271.0,83.0,"PRKCE,AKT3,REL,SOCS1,CACNA1A,CACNA2D3,SLC27A3",0.7034749744200064,0.44943164647875583]
["TR2","IPA","NRF2-mediated Oxidative Stress Response","NRF2-mediated Oxidative Stress Response",2.1819900829495342,0.3897313128240673,4.0,61.0,125.0,"HRAS,MAPK1,DNAJC7,AKR1A1",0.7107925856465609,0.718532134170359]
["TR11","IPA","Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes","Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes",2.178479499770036,0.3897313128240673,10.0,787.0,53.0,"CBL,PIK3CG,PRKCQ,CRK,ARPC1A,PLD6,FCGR2A,GAB2,FCGR3A,MYO5A",0.7131329790897313,0.720777907347652]
["PR9","ADAMs","MMP9","MMP9",2.1761819274106795,0.34659430006539854,4.0,24.0,35.0,"APP,SPARC,PPBP,PF4",0.31993320006036774,0.78263123912912]
["TR20","IPA","Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency","Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",2.1737962016965477,0.3897313128240673,3.0,69.0,57.0,"KRAS,PIK3CB,RIF1",0.7136930477205876,0.720990421301135]
["TR16","IPA","Mitochondrial Dysfunction","Mitochondrial Dysfunction",2.173498144247406,0.3897313128240673,17.0,1114.0,82.0,"NCSTN,CYCS,GLRX2,GPX7,COX6C,COX11,NDUFA6,NDUFAB1,NDUFB2,NDUFB7,NDUFS3,NDUFS5,NDUFV2,UQCRH,COX17,NDUFA12,COX4I2",0.7136930477205876,0.720990421301135]
["TR25","IPA","Fc Epsilon RI Signaling","Fc Epsilon RI Signaling",2.1719489797722114,0.3897313128240673,9.0,505.0,69.0,"ATM,PLCG1,AKT3,INPP5D,MAPK14,PLA2G6,FYN,GAB1,IL3",0.7136930477205876,0.720990421301135]
["TR22","IPA","Ephrin B Signaling","Ephrin B Signaling",2.1674378778102708,0.3906998338666239,15.0,1644.0,48.0,"MRAS,GNAI3,GNB1,GNG3,GNG2,GNB4,PTK2,ROCK1,ROCK2,VAV3,ITSN1,CTNNB1,AXIN1,ABI1,ITSN2",0.7177592955274589,0.7249820227783441]
["TR22","IPA","VEGF Signaling","VEGF Signaling",2.160683268760579,0.39372372646952447,17.0,1644.0,57.0,"ATM,BAD,KRAS,PIK3C2A,PIK3CA,PRKCA,MRAS,PTPN11,ACTA2,PTK2,ROCK1,ROCK2,PDGFC,VEGFA,VEGFB,ARNT,EIF2B5",0.7246539535693415,0.7305181643767568]
["TR20","IPA","PDGF Signaling","PDGF Signaling",2.1528172130574132,0.3972462843385246,3.0,69.0,58.0,"KRAS,PIK3CB,INPP5B",0.7246539535693415,0.7305181643767568]
["TR13","IPA","Phospholipase C Signaling","Phospholipase C Signaling",2.1499983526557074,0.3972462843385246,8.0,172.0,166.0,"PRKCH,PPP3CC,MPRIP,CD247,NFATC2,ADCY9,ZAP70,AHNAK",0.7246539535693415,0.7305181643767568]
["PR6","IPA","VEGF Signaling","VEGF Signaling",2.149391858183025,1.0,6.0,78.0,25.0,"PRKCB,MAPK1,MAPK3,SRC,PTPN6,PTPN11",0.7246539535693415,0.7305181643767568]
["TR31","IPA","SAPK/JNK Signaling","SAPK/JNK Signaling",2.1467536859596836,0.3972462843385246,6.0,229.0,76.0,"DUSP8,GNA12,GNA13,GNG10,MAP3K2,DAXX",0.7246539535693415,0.7305181643767568]
["PR35","IPA","Prostate Cancer Signaling","Prostate Cancer Signaling",2.1420976166130954,1.0,2.0,8.0,18.0,"CDKN1B,PTEN",0.7246539535693415,0.7305181643767568]
["TR16","IPA","SAPK/JNK Signaling","SAPK/JNK Signaling",2.1420536258717897,0.39852655795842,16.0,1114.0,76.0,"ATM,MAP3K5,PIK3CD,PIK3R6,GNB2,IRS1,GNB5,CRKL,SOS1,CD3D,CD3G,TRA,TRB,MAP3K3,MAP3K13,ZAK",0.7246539535693415,0.7305181643767568]
["PR6","IPA","FLT3 Signaling in Hematopoietic Progenitor Cells","FLT3 Signaling in Hematopoietic Progenitor Cells",2.139652636147952,1.0,5.0,78.0,18.0,"MAPK1,MAPK3,PTPN11,PDPK1,RPS6KA3",0.7246539535693415,0.7305181643767568]
["PR6","IPA","P2Y Purigenic Receptor Signaling Pathway","P2Y Purigenic Receptor Signaling Pathway",2.139652636147952,1.0,5.0,78.0,18.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PRKACA",0.7246539535693415,0.7305181643767568]
["PR6","IPA","Thrombopoietin Signaling","Thrombopoietin Signaling",2.139652636147952,1.0,5.0,78.0,18.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PTPN11",0.7246539535693415,0.7305181643767568]
["PR23","IPA","Differential Regulation of Cytokine Production in Macrophages and T Helper Cells by IL-17A and IL-17F","Differential Regulation of Cytokine Production in Macrophages and T Helper Cells by IL-17A and IL-17F",2.139001852396791,1.0,2.0,10.0,16.0,"IL6,IL3",0.7246539535693415,0.7305181643767568]
["PR31","IPA","Renal Cell Carcinoma Signaling","Renal Cell Carcinoma Signaling",2.139001852396791,1.0,2.0,9.0,16.0,"PAK7,HGF",0.7246539535693415,0.7305181643767568]
["TR11","IPA","p38 MAPK Signaling","p38 MAPK Signaling",2.1375572017757443,0.3996464711906567,11.0,787.0,62.0,"MAP2K4,TNFRSF1A,DUSP1,CREB5,TRAF6,IL1R1,IL1RAP,H3F3B,ATF1,IL1R2,IRAK4",0.7246539535693415,0.7305181643767568]
["PR6","IPA","NRF2-mediated Oxidative Stress Response","NRF2-mediated Oxidative Stress Response",2.124332885620378,1.0,7.0,78.0,33.0,"PRKCB,PRKCQ,MAPK1,MAPK3,AKR7A2,FTH1,STIP1",0.7437681281320474,0.7496814577175682]
["PR17","h.all.v5.0.entrez","HALLMARK_XENOBIOTIC_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_XENOBIOTIC_METABOLISM",2.123605248727697,1.0,3.0,12.0,38.0,"KYNU,CRP,ITIH4",0.566839835850685,0.6459087728666932]
["TR24","IPA","Breast Cancer Regulation by Stathmin1","Breast Cancer Regulation by Stathmin1",2.1123781755178745,0.41754504034135664,5.0,108.0,116.0,"TUBB1,GNG7,GNG11,PRKAR2B,CALM3",0.7551282944960606,0.7608161893463253]
["PR6","IPA","Leukocyte Extravasation Signaling","Leukocyte Extravasation Signaling",2.1123091484670216,1.0,9.0,78.0,50.0,"PRKCB,PRKCQ,MAPK1,SRC,PTPN11,CRK,MSN,BTK,FER",0.7551282944960606,0.7608161893463253]
["TR20","IPA","Acute Myeloid Leukemia Signaling","Acute Myeloid Leukemia Signaling",2.112047727384962,0.41754504034135664,3.0,69.0,60.0,"KRAS,PIK3CB,REL",0.7551282944960606,0.7608161893463253]
["PR9","h.all.v5.0.entrez","HALLMARK_ANGIOGENESIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ANGIOGENESIS",2.1058336333230656,1.0,3.0,24.0,19.0,"PF4,APP,PDGFA",0.5787060926908572,0.6572394650417089]
["PR51","IPA","IGF-1 Signaling","IGF-1 Signaling",2.104112402918843,1.0,2.0,5.0,31.0,"IGFBP3,IGFBP5",0.763195978951233,0.7692173104345431]
["TR4","IPA","Protein Ubiquitination Pathway","Protein Ubiquitination Pathway",2.103400768645218,0.42028571581795604,5.0,76.0,166.0,"DNAJC3,CUL1,PSMA5,PSMB2,PSME2",0.763195978951233,0.7692173104345431]
["TR1","IPA","IL-10 Signaling","IL-10 Signaling",2.101804312335201,0.42028571581795604,5.0,271.0,47.0,"REL,IL1RN,FCGR2B,CCR1,BLVRA",0.763195978951233,0.44943164647875583]
["TR22","IPA","Angiopoietin Signaling","Angiopoietin Signaling",2.098583849679218,0.42028571581795604,13.0,1644.0,40.0,"ATM,BAD,KRAS,PIK3C2A,PIK3CA,MRAS,PTPN11,RASA1,NFKB1,NFKB2,REL,PTK2,ANGPT4",0.7655906129011214,0.7743548930569982]
["TR15","IPA","Nur77 Signaling in T Lymphocytes","Nur77 Signaling in T Lymphocytes",2.0965253951056964,0.42028571581795604,2.0,30.0,46.0,"HLA-DMB,HLA-DRA",0.7659546367176909,0.7746064045662352]
["PR7","IPA","Hereditary Breast Cancer Signaling","Hereditary Breast Cancer Signaling",2.0916609555228893,1.0,3.0,39.0,12.0,"KRAS,CHEK2,CCNB1",0.7705960838216285,0.7788408956441872]
["PR23","IPA","MSP-RON Signaling Pathway","MSP-RON Signaling Pathway",2.0865716083559662,1.0,2.0,10.0,17.0,"TLR2,IL3",0.7705960838216285,0.7788408956441872]
["PR23","IPA","TREM1 Signaling","TREM1 Signaling",2.0865716083559662,1.0,2.0,10.0,17.0,"IL6,TLR2",0.7705960838216285,0.7788408956441872]
["PR50","IPA","Thyroid Cancer Signaling","Thyroid Cancer Signaling",2.0865716083559662,1.0,2.0,9.0,17.0,"CXCL1,KLK3",0.7705960838216285,0.7788408956441872]
["PR6","h.all.v5.0.entrez","HALLMARK_FATTY_ACID_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_FATTY_ACID_METABOLISM",2.0860770181742727,1.0,4.0,78.0,12.0,"MIF,PSME1,METAP1,PRDX6",0.5937648686635709,0.6721961608418859]
["TR8","IPA","Role of IL-17A in Arthritis","Role of IL-17A in Arthritis",2.0815283265034763,0.429997154118306,2.0,36.0,39.0,"NFKBIE,CCL2",0.7763485365574437,0.7845416859185851]
["PR37","IPA","Acute Phase Response Signaling","Acute Phase Response Signaling",2.078672276109185,1.0,3.0,7.0,71.0,"MAPK13,FN1,C2",0.7782282435380699,0.7863287208030676]
["TR5","IPA","Role of NFAT in Regulation of the Immune Response","Role of NFAT in Regulation of the Immune Response",2.0730588493682403,0.429997154118306,3.0,31.0,139.0,"CHP1,BTK,MEF2A",0.7787059096062982,0.786947126861294]
["TR20","IPA","HMGB1 Signaling","HMGB1 Signaling",2.0727747787001696,0.429997154118306,3.0,69.0,62.0,"KRAS,PIK3CB,REL",0.7787059096062982,0.786947126861294]
["TR32","IPA","Telomerase Signaling","Telomerase Signaling",2.0727747787001696,0.429997154118306,3.0,62.0,69.0,"PIK3CA,PPP2CA,HDAC8",0.7787059096062982,0.786947126861294]
["TR1","IPA","Dendritic Cell Maturation","Dendritic Cell Maturation",2.0712567519590257,0.429997154118306,8.0,271.0,109.0,"AKT3,REL,STAT1,STAT2,IL1RN,JAK2,MYD88,FCGR2B",0.7787059096062982,0.44943164647875583]
["TR1","IPA","Erythropoietin Signaling","Erythropoietin Signaling",2.0633396938712267,0.43488770460331594,5.0,271.0,48.0,"PRKCE,AKT3,REL,JAK2,SOCS1",0.7898079591027541,0.44943164647875583]
["PR6","h.all.v5.0.entrez","HALLMARK_MYC_TARGETS_V1","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MYC_TARGETS_V1",2.0610037219729707,1.0,6.0,78.0,26.0,"KPNB1,PA2G4,PPIA,RAN,ACP1,EIF4G2",0.6164413922004893,0.693703459857819]
["TR15","IPA","Colorectal Cancer Metastasis Signaling","Colorectal Cancer Metastasis Signaling",2.0544947045191373,0.4355371276592895,3.0,30.0,146.0,"SRC,FZD1,ADRBK2",0.7917998399147482,0.8053148101624034]
["TR20","IPA","RANK Signaling in Osteoclasts","RANK Signaling in Osteoclasts",2.053668891238831,0.4355371276592895,3.0,69.0,63.0,"PIK3CB,PPP3R1,REL",0.7917998399147482,0.8053148101624034]
["PR21","h.all.v5.0.entrez","HALLMARK_INTERFERON_GAMMA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_GAMMA_RESPONSE",2.0530940301487512,1.0,3.0,13.0,37.0,"CD274,CD86,PSMA2",0.6164413922004893,0.693703459857819]
["TR11","IPA","IL-10 Signaling","IL-10 Signaling",2.0515654947279027,0.4355371276592895,9.0,787.0,47.0,"FOS,MAP2K4,TRAF6,IL1R1,IL1RAP,FCGR2A,FCGR2C,IL1R2,IL10RB",0.7917998399147482,0.8053148101624034]
["PR37","IPA","Corticotropin Releasing Hormone Signaling","Corticotropin Releasing Hormone Signaling",2.0511145124668997,1.0,2.0,7.0,23.0,"MAPK13,POMC",0.7917998399147482,0.8053148101624034]
["TR31","IPA","D-myo-inositol-5-phosphate Metabolism","D-myo-inositol-5-phosphate Metabolism",2.050873374257238,0.4355371276592895,7.0,229.0,104.0,"SYNJ1,DUSP8,PTPN7,PTPN12,MTMR6,NUDT4,TMEM55A",0.7917998399147482,0.8053148101624034]
["PR51","IPA","RAR Activation","RAR Activation",2.0506011647233766,1.0,2.0,5.0,33.0,"PRKCA,IGFBP3",0.7917998399147482,0.8053148101624034]
["PR6","IPA","Natural Killer Cell Signaling","Natural Killer Cell Signaling",2.0500603761102085,1.0,7.0,78.0,34.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PTPN6,PTPN11,FYN",0.7917998399147482,0.8053148101624034]
["TR15","IPA","Calcium-induced T Lymphocyte Apoptosis","Calcium-induced T Lymphocyte Apoptosis",2.0434313361940144,0.4401110068387271,2.0,30.0,49.0,"HLA-DMB,HLA-DRA",0.8008132571078679,0.8143501360091576]
["TR8","IPA","Death Receptor Signaling","Death Receptor Signaling",2.039452685981263,0.4412200017854586,2.0,36.0,41.0,"NFKBIE,CASP10",0.8050140134055207,0.8184903537417814]
["PR6","IPA","AMPK Signaling","AMPK Signaling",2.032134235160565,1.0,5.0,78.0,19.0,"MAPK1,SRC,PDPK1,AK1,PRKACA",0.8091748309787832,0.8223305404768168]
["PR6","IPA","Chronic Myeloid Leukemia Signaling","Chronic Myeloid Leukemia Signaling",2.032134235160565,1.0,5.0,78.0,19.0,"MAPK1,MAPK3,PTPN11,CRK,PA2G4",0.8091748309787832,0.8223305404768168]
["PR6","IPA","ErbB4 Signaling","ErbB4 Signaling",2.032134235160565,1.0,5.0,78.0,19.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PDPK1",0.8091748309787832,0.8223305404768168]
["TR27","IPA","Allograft Rejection Signaling","Allograft Rejection Signaling",2.0260507750727355,0.4520541518158478,7.0,690.0,36.0,"IL5,HLA-DMA,HLA-DPA1,HLA-DQA1,HLA-DQB1,HLA-DRB1,TRA",0.8174209566296862,0.8305814235170697]
["TR3","IPA","Insulin Receptor Signaling","Insulin Receptor Signaling",2.017916325591437,0.45754684568438353,3.0,54.0,83.0,"GSK3B,PIK3CB,SGK1",0.8296723814789608,0.8428998984505828]
["TR8","IPA","Molecular Mechanisms of Cancer","Molecular Mechanisms of Cancer",2.0151285388012186,0.45754684568438353,4.0,36.0,239.0,"NFKBIE,PRKAR1A,CDKN1A,CASP10",0.8318159827311464,0.8449481812930716]
["TR31","IPA","3-phosphoinositide Degradation","3-phosphoinositide Degradation",2.007504365440324,0.4603854448192496,7.0,229.0,106.0,"SYNJ1,DUSP8,PTPN7,PTPN12,MTMR6,NUDT4,TMEM55A",0.8405878754435806,0.8530947875579599]
["TR22","IPA","Gαq Signaling","Gαq Signaling",2.0068386421006843,0.4603854448192496,25.0,1644.0,97.0,"ATM,PIK3C2A,PIK3CA,PRKCA,MRAS,PLCB1,PRKD3,PPP3CA,NFKB1,NFKB2,REL,GNAI3,GNB1,GNG3,GNG2,GNB4,CSK,ROCK1,ROCK2,RHOB,FNBP1,RHOF,RHOT1,ITPR2,RGS18",0.8405878754435806,0.8530947875579599]
["TR1","pSS GWAS","nearby genes","nearby genes",2.0063841853804774,0.4910787481217711,2.0,271.0,6.0,"GTF2I,TNFAIP3",0.7292014681040013,0.029562221679891948]
["PR35","h.all.v5.0.entrez","HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION",2.0030113455997003,1.0,3.0,8.0,65.0,"TNFRSF12A,FGF2,MMP3",0.649329057701432,0.718369298522406]
["PR29","IPA","Role of Tissue Factor in Cancer","Role of Tissue Factor in Cancer",2.0026468418789216,1.0,3.0,11.0,46.0,"MAPK12,IL8,CSF1",0.8405878754435806,0.8530947875579599]
["PR2","IPA","Oncostatin M Signaling","Oncostatin M Signaling",2.001933529653951,1.0,2.0,12.0,14.0,"MMP1,TIMP3",0.8405878754435806,0.8530947875579599]
["TR18","IPA","Estrogen Receptor Signaling","Estrogen Receptor Signaling",2.000963345706478,0.46102642015859646,30.0,2408.0,85.0,"NRAS,MAP2K2,RRAS2,TAF9,EP300,SOS1,CCNH,GTF2E1,GTF2F2,POLR2A,POLR2K,TAF1,TAF2,TAF4B,TAF5,TAF11,NCOA2,TAF9B,GTF2H5,NRIP1,CCNC,CDK8,HNRNPD,MED21,MED12,SRA1,MED16,SPEN,MED13L,MED4",0.8405878754435806,0.8530947875579599]
["TR22","IPA","Death Receptor Signaling","Death Receptor Signaling",2.000701924038528,0.46102642015859646,13.0,1644.0,41.0,"MAPK8,NFKB1,NFKB2,REL,TANK,TBK1,MAP2K7,FAS,BIRC2,XIAP,CASP3,CRADD,TNFRSF10B",0.8405878754435806,0.8530947875579599]
["PR51","ADAMs","MMP9","MMP9",2.000389428553441,0.41562714316303884,2.0,5.0,35.0,"IGFBP3,NRP1",0.39964148381061454,0.78263123912912]
["TR24","IPA","ERK/MAPK Signaling","ERK/MAPK Signaling",1.9938536108840565,0.46540826353607206,5.0,108.0,124.0,"PRKAR2B,ITGA2B,ITGB3,ITGB5,PLA2G12A",0.8507616443493128,0.8632945892052407]
["PR14","h.all.v5.0.entrez","HALLMARK_HEDGEHOG_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HEDGEHOG_SIGNALING",1.9924121499055258,1.0,4.0,113.0,9.0,"CNTFR,NRCAM,L1CAM,PLG",0.649329057701432,0.718369298522406]
["PR47","h.all.v5.0.entrez","HALLMARK_MTORC1_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MTORC1_SIGNALING",1.9915050220008426,1.0,3.0,20.0,25.0,"PGK1,GOT1,PPA1",0.649329057701432,0.718369298522406]
["PR31","IPA","IL-17A Signaling in Gastric Cells","IL-17A Signaling in Gastric Cells",1.990970024098242,1.0,2.0,9.0,19.0,"TNF,IL17RC",0.8532454927311528,0.8656902926120816]
["PR7","IPA","IL-4 Signaling","IL-4 Signaling",1.9888679532458706,1.0,3.0,39.0,13.0,"KRAS,IL4,IL13RA1",0.8542098784585748,0.8665448281132941]
["TR28","IPA","3-phosphoinositide Biosynthesis","3-phosphoinositide Biosynthesis",1.985589125157878,0.47138495532091007,7.0,213.0,115.0,"PIK3C2A,PPP3CB,PPP3R1,PIP5K1B,RNGTT,MTMR9,SSH2",0.8575074282719993,0.8697665539799007]
["TR20","IPA","Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes","Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes",1.9805266682071705,0.47312016472507407,3.0,69.0,67.0,"KRAS,PPP3R1,REL",0.8637685106395198,0.8758712979792385]
["PR36","h.all.v5.0.entrez","HALLMARK_MTORC1_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MTORC1_SIGNALING",1.9798781059534043,1.0,2.0,7.0,25.0,"AURKA,PSME3",0.649329057701432,0.718369298522406]
["PR6","IPA","Gαs Signaling","Gαs Signaling",1.9792362924031468,1.0,3.0,78.0,7.0,"MAPK1,MAPK3,PRKACA",0.8637685106395198,0.8758712979792385]
["TR4","h.all.v5.0.entrez","HALLMARK_BILE_ACID_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_BILE_ACID_METABOLISM",1.977371571986514,0.36739108114771923,3.0,76.0,61.0,"IDH2,DHCR24,GSTK1",0.649329057701432,0.718369298522406]
["PR48","h.all.v5.0.entrez","HALLMARK_IL6_JAK_STAT3_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_IL6_JAK_STAT3_SIGNALING",1.9765169763916328,1.0,3.0,11.0,47.0,"TGFB1,IL4R,IL17RB",0.649329057701432,0.718369298522406]
["PR51","h.all.v5.0.entrez","HALLMARK_HYPOXIA","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HYPOXIA",1.9764020894927474,1.0,2.0,5.0,36.0,"IGFBP3,PRKCA",0.649329057701432,0.718369298522406]
["TR3","IPA","Glioblastoma Multiforme Signaling","Glioblastoma Multiforme Signaling",1.9759257625271007,0.47312016472507407,3.0,54.0,86.0,"GSK3B,PIK3CB,TCF3",0.8640479627154135,0.8759124499493693]
["TR3","IPA","Ovarian Cancer Signaling","Ovarian Cancer Signaling",1.9759257625271007,0.47312016472507407,3.0,54.0,86.0,"GSK3B,PIK3CB,TCF3",0.8640479627154135,0.8759124499493693]
["TR22","IPA","Pancreatic Adenocarcinoma Signaling","Pancreatic Adenocarcinoma Signaling",1.9724113719288847,0.4736285175307433,22.0,1644.0,83.0,"ATM,BAD,CDKN1B,KRAS,PIK3C2A,PIK3CA,MAPK8,NFKB1,NFKB2,REL,CDK2,ABL1,PDGFC,TGFB1,VEGFA,VEGFB,SMAD2,SMAD4,TGFBR1,TFDP1,CDKN2B,RALBP1",0.867912319378579,0.8797095916940023]
["PR19","h.all.v5.0.entrez","HALLMARK_COAGULATION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_COAGULATION",1.9661071759025515,1.0,3.0,8.0,67.0,"KLKB1,MMP8,F11",0.649329057701432,0.71858651996082]
["TR31","IPA","Cardiac β-adrenergic Signaling","Cardiac β-adrenergic Signaling",1.9656115187997525,0.4736285175307433,6.0,229.0,83.0,"GNA12,GNA13,GNG10,PDE4B,AKAP1,TDP2",0.8784256709488074,0.8902450255121356]
["TR1","IPA","iNOS Signaling","iNOS Signaling",1.9615504717953889,0.4736285175307433,4.0,271.0,33.0,"REL,STAT1,JAK2,MYD88",0.8820691572941689,0.4730327677690785]
["TR9","IPA","Gαi Signaling","Gαi Signaling",1.9606894669566852,0.4736285175307433,6.0,269.0,71.0,"RRAS,SOS1,SOS2,RALGDS,CNR1,RGS12",0.8820691572941689,0.8970322866886994]
["TR24","IPA","fMLP Signaling in Neutrophils","fMLP Signaling in Neutrophils",1.9547179011201945,0.4736285175307433,4.0,108.0,82.0,"GNAZ,GNG7,GNG11,CALM3",0.8843363702906564,0.8981859024589608]
["TR22","h.all.v5.0.entrez","HALLMARK_PI3K_AKT_MTOR_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PI3K_AKT_MTOR_SIGNALING",1.951441536427343,0.36739108114771923,19.0,1644.0,69.0,"PDK1,CDKN1B,CDK1,ARHGDIA,IL2RG,PTPN11,CDK2,RPS6KA3,MAPK8,ACTR2,PIKFYVE,TBK1,ITPR2,PLCB1,VAV3,IL4,CAB39L,PRKAG1,SMAD2",0.649329057701432,0.71858651996082]
["TR27","IPA","Nur77 Signaling in T Lymphocytes","Nur77 Signaling in T Lymphocytes",1.9511735100850864,0.4736285175307433,8.0,690.0,46.0,"PPP3R1,HLA-DMA,HLA-DQA1,HLA-DQB1,HLA-DRB1,TRA,HDAC1,MAPK7",0.8843363702906564,0.8981859024589608]
["PR6","IPA","Amyloid Processing","Amyloid Processing",1.950764398037205,1.0,4.0,78.0,13.0,"MAPK1,MAPK3,PRKACA,CSNK2A1",0.8843363702906564,0.8981859024589608]
["PR6","IPA","ERK5 Signaling","ERK5 Signaling",1.950764398037205,1.0,4.0,78.0,13.0,"SRC,YWHAB,PTPN11,RPS6KA3",0.8843363702906564,0.8981859024589608]
["TR15","IPA","IL-4 Signaling","IL-4 Signaling",1.9468545173448801,0.4736285175307433,2.0,30.0,55.0,"HLA-DMB,HLA-DRA",0.8843363702906564,0.8981859024589608]
["TR20","IPA","Chronic Myeloid Leukemia Signaling","Chronic Myeloid Leukemia Signaling",1.9457863324335023,0.4736285175307433,3.0,69.0,69.0,"KRAS,PIK3CB,REL",0.8843363702906564,0.8981859024589608]
["TR20","IPA","Fc Epsilon RI Signaling","Fc Epsilon RI Signaling",1.9457863324335023,0.4736285175307433,3.0,69.0,69.0,"KRAS,PIK3CB,INPP5B",0.8843363702906564,0.8981859024589608]
["TR20","IPA","HGF Signaling","HGF Signaling",1.9457863324335023,0.4736285175307433,3.0,69.0,69.0,"KRAS,PIK3CB,ELF1",0.8843363702906564,0.8981859024589608]
["TR20","IPA","Telomerase Signaling","Telomerase Signaling",1.9457863324335023,0.4736285175307433,3.0,69.0,69.0,"KRAS,PIK3CB,ELF1",0.8843363702906564,0.8981859024589608]
["TR1","h.all.v5.0.entrez","HALLMARK_P53_PATHWAY","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_P53_PATHWAY",1.9455067506000254,0.36739108114771923,9.0,271.0,138.0,"ATF3,RNF19B,TAP1,BAK1,SOCS1,IFI30,TRAFD1,H2AFJ,RHBDF2",0.649329057701432,0.12187137573354227]
["TR10","IPA","IL-15 Signaling","IL-15 Signaling",1.9431225797577212,0.4736285175307433,2.0,36.0,46.0,"IL15,STAT6",0.8866983174715952,0.900461108504831]
["PR1","IPA","Dendritic Cell Maturation","Dendritic Cell Maturation",1.9406737061215478,1.0,8.0,83.0,41.0,"PIK3CA,TNFRSF1A,LTA,TNFRSF1B,B2M,IGHG1,ICAM1,FCGR3B",0.8886374316651159,0.4730327677690785]
["TR22","IPA","TNFR1 Signaling","TNFR1 Signaling",1.9364608687149554,0.4736285175307433,11.0,1644.0,33.0,"MAPK8,NFKB1,NFKB2,REL,TANK,MAP3K1,BIRC2,XIAP,CASP3,CRADD,MAP4K2",0.8916562522470821,0.907621164594286]
["PR6","IPA","IL-3 Signaling","IL-3 Signaling",1.9322685797812837,1.0,5.0,78.0,20.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PTPN6",0.8916562522470821,0.907621164594286]
["TR9","h.all.v5.0.entrez","HALLMARK_CHOLESTEROL_HOMEOSTASIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_CHOLESTEROL_HOMEOSTASIS",1.9321830459359852,0.36739108114771923,5.0,269.0,52.0,"LDLR,CYP51A1,SCD,PMVK,ANTXR2",0.649329057701432,0.71858651996082]
["TR9","IPA","FLT3 Signaling in Hematopoietic Progenitor Cells","FLT3 Signaling in Hematopoietic Progenitor Cells",1.9321830459359852,0.4736285175307433,5.0,269.0,52.0,"RRAS,MTOR,CREB1,SOS1,SOS2",0.8916562522470821,0.907621164594286]
["TR15","IPA","T Helper Cell Differentiation","T Helper Cell Differentiation",1.9318501788520295,0.4736285175307433,2.0,30.0,56.0,"HLA-DMB,HLA-DRA",0.8916562522470821,0.907621164594286]
["TR4","h.all.v5.0.entrez","HALLMARK_INTERFERON_GAMMA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_GAMMA_RESPONSE",1.9314662940743792,0.36739108114771923,5.0,76.0,183.0,"IL15RA,HIF1A,PSME2,NLRC5,PSMB2",0.649329057701432,0.71858651996082]
["PR52","h.all.v5.0.entrez","HALLMARK_XENOBIOTIC_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_XENOBIOTIC_METABOLISM",1.9304609861738435,1.0,2.0,5.0,38.0,"F10,PROS1",0.649329057701432,0.71858651996082]
["TR20","IPA","Gα12/13 Signaling","Gα12/13 Signaling",1.9288423984110539,0.4736285175307433,3.0,69.0,70.0,"KRAS,PIK3CB,REL",0.8916562522470821,0.907621164594286]
["TR20","IPA","IL-6 Signaling","IL-6 Signaling",1.9288423984110539,0.4736285175307433,3.0,69.0,70.0,"KRAS,PIK3CB,REL",0.8916562522470821,0.907621164594286]
["TR20","IPA","Renin-Angiotensin Signaling","Renin-Angiotensin Signaling",1.9288423984110539,0.4736285175307433,3.0,69.0,70.0,"KRAS,PIK3CB,REL",0.8916562522470821,0.907621164594286]
["TR16","h.all.v5.0.entrez","HALLMARK_G2M_CHECKPOINT","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_G2M_CHECKPOINT",1.9287220515161325,0.36739108114771923,25.0,1114.0,143.0,"MARCKS,RACGAP1,KIF15,BIRC5,TOP2A,CENPF,KATNA1,AURKA,NUSAP1,CCNB2,BUB1,NOTCH2,CCNA2,CHEK1,DBF4,CDKN2C,FANCC,CHAF1A,HN1,DTYMK,UPF1,CUL5,ORC5,SLC12A2,ZAK",0.649329057701432,0.71858651996082]
["TR13","IPA","iCOS-iCOSL Signaling in T Helper Cells","iCOS-iCOSL Signaling in T Helper Cells",1.9273616881120272,0.4736285175307433,5.0,172.0,81.0,"PPP3CC,CD247,NFATC2,ZAP70,IL2RB",0.8916991542130829,0.907621164594286]
["TR10","IPA","Role of JAK1 and JAK3 in γc Cytokine Signaling","Role of JAK1 and JAK3 in γc Cytokine Signaling",1.9251958918890522,0.4736285175307433,2.0,36.0,47.0,"IL15,STAT6",0.893159921118033,0.9089804593564933]
["TR1","IPA","JAK/Stat Signaling","JAK/Stat Signaling",1.9192864208872265,0.47750792240464796,5.0,271.0,52.0,"AKT3,STAT1,STAT2,JAK2,SOCS1",0.9023782755851577,0.4730327677690785]
["PR3","IPA","LXR/RXR Activation","LXR/RXR Activation",1.9175008225486925,1.0,3.0,12.0,45.0,"LBP,AGT,SAA1",0.9030857484536338,0.9220172057026895]
["TR11","h.all.v5.0.entrez","HALLMARK_HYPOXIA","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HYPOXIA",1.9069318215302153,0.36739108114771923,17.0,787.0,122.0,"PPP1R15A,DUSP1,NFIL3,TIPARP,FOSL2,FOS,FAM162A,RBPJ,PDK3,GAA,CCRN4L,IDS,KLF7,CASP6,SLC6A6,AKAP12,TGM2",0.6550968821378281,0.71858651996082]
["TR18","IPA","mTOR Signaling","mTOR Signaling",1.9068399874450905,0.48873462638688414,39.0,2408.0,118.0,"ATM,NRAS,PIK3C3,PIK3CG,PRKCB,PRKCI,TSC2,RRAS2,PRKD3,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R5D,PPM1L,RPS6KB1,PDPK1,INSR,PRKAB2,RHOG,RHOU,EIF4E,EIF4A2,FAU,EIF3E,RPS2,RPS7,RPS9,RPS14,RPS15A,RPS17,RPS18,RPS21,RPS23,RPS24,RPS25,RPS27A,RPS29,EIF3J,MAPKAP1",0.9205594402194187,0.9399602697098283]
["PR23","IPA","Hematopoiesis from Pluripotent Stem Cells","Hematopoiesis from Pluripotent Stem Cells",1.9056034811267082,1.0,2.0,10.0,21.0,"IL6,IL3",0.9205594402194187,0.9399602697098283]
["TR14","h.all.v5.0.entrez","HALLMARK_IL2_STAT5_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_IL2_STAT5_SIGNALING",1.902634544112188,0.36739108114771923,6.0,120.0,163.0,"CD83,SYNGR2,IRF8,CD79B,AKAP2,SWAP70",0.6550968821378281,0.71858651996082]
["TR2","IPA","Rac Signaling","Rac Signaling",1.9024164254022506,0.4910836280693362,3.0,61.0,81.0,"HRAS,MAPK1,ELK4",0.9205594402194187,0.9399602697098283]
["PR15","IPA","Reelin Signaling in Neurons","Reelin Signaling in Neurons",1.8987241421473149,1.0,2.0,10.0,19.0,"MAPK9,YES1",0.9205594402194187,0.9399602697098283]
["PR6","IPA","14-3-3-mediated Signaling","14-3-3-mediated Signaling",1.8981644885107285,1.0,6.0,78.0,28.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,YWHAB",0.9205594402194187,0.9399602697098283]
["TR24","IPA","Cardiac Hypertrophy Signaling","Cardiac Hypertrophy Signaling",1.8978203190785123,0.49335619597465985,5.0,108.0,131.0,"GNAZ,GNG7,GNG11,PRKAR2B,CALM3",0.9205594402194187,0.9399602697098283]
["PR35","h.all.v5.0.entrez","HALLMARK_UV_RESPONSE_DN","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UV_RESPONSE_DN",1.89581046015482,1.0,2.0,8.0,24.0,"CDKN1B,PTEN",0.6550968821378281,0.71858651996082]
["PR19","IPA","Coagulation System","Coagulation System",1.89581046015482,1.0,2.0,8.0,24.0,"KLKB1,F11",0.9205594402194187,0.9399602697098283]
["PR35","IPA","PI3K/AKT Signaling","PI3K/AKT Signaling",1.89581046015482,1.0,2.0,8.0,24.0,"CDKN1B,PTEN",0.9205594402194187,0.9399602697098283]
["PR9","h.all.v5.0.entrez","HALLMARK_TGF_BETA_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TGF_BETA_SIGNALING",1.8958104601548198,1.0,2.0,24.0,8.0,"SERPINE1,THBS1",0.6550968821378281,0.71858651996082]
["TR20","IPA","Prostate Cancer Signaling","Prostate Cancer Signaling",1.8957663892552294,0.49335619597465985,3.0,69.0,72.0,"KRAS,PIK3CB,REL",0.9205594402194187,0.9399602697098283]
["PR1","IPA","Death Receptor Signaling","Death Receptor Signaling",1.8949840818733248,1.0,5.0,83.0,19.0,"TNFRSF1A,TNFRSF1B,HTRA2,TNFRSF25,TNFRSF21",0.9205594402194187,0.4730327677690785]
["PR9","IPA","Ephrin Receptor Signaling","Ephrin Receptor Signaling",1.8928713076208967,1.0,4.0,24.0,42.0,"ITGA2B,PDGFA,PDGFB,ANGPT1",0.9220838281225613,0.9430718117906881]
["TR28","IPA","PAK Signaling","PAK Signaling",1.8894826950273187,0.4978979362030046,5.0,213.0,67.0,"PIK3C2A,ITGAL,WASL,NCK1,NCK2",0.9263375614387288,0.9472801839164169]
["TR11","h.all.v5.0.entrez","HALLMARK_MYC_TARGETS_V1","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MYC_TARGETS_V1",1.8891530570528823,0.36739108114771923,19.0,787.0,142.0,"PCNA,MCM6,G3BP1,IARS,MCM4,RANBP1,POLD2,SNRPA1,C1QBP,SSBP1,TCP1,DDX18,CCT4,COX5A,MRPL9,TUFM,ILF2,NOP16,PHB",0.6550968821378281,0.71858651996082]
["TR4","h.all.v5.0.entrez","HALLMARK_HYPOXIA","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HYPOXIA",1.8876332997737866,0.36739108114771923,4.0,76.0,122.0,"IRS2,RBPJ,PDK3,PLAC8",0.6550968821378281,0.71858651996082]
["TR4","IPA","IGF-1 Signaling","IGF-1 Signaling",1.884562591710714,0.5009203007487878,3.0,76.0,66.0,"MAPK1,IRS2,IGF1R",0.9339079386306353,0.9548793233023765]
["TR14","IPA","Phospholipase C Signaling","Phospholipase C Signaling",1.8666294133602155,0.5173743071780897,6.0,120.0,166.0,"PPP1R14A,IGH,IGL,CD79A,CD79B,BLNK",0.9644572128220502,0.9853938284740591]
["PR31","IPA","Macropinocytosis Signaling","Macropinocytosis Signaling",1.8661394937150646,1.0,2.0,9.0,22.0,"INS,HGF",0.9644572128220502,0.9853938284740591]
["PR50","IPA","Role of IL-17F in Allergic Inflammatory Airway Diseases","Role of IL-17F in Allergic Inflammatory Airway Diseases",1.8661394937150646,1.0,2.0,9.0,22.0,"CXCL1,CXCL5",0.9644572128220502,0.9853938284740591]
["TR5","IPA","Phospholipase C Signaling","Phospholipase C Signaling",1.8641993082290824,0.5173743071780897,3.0,31.0,166.0,"CHP1,BTK,MEF2A",0.9644572128220502,0.9853938284740591]
["TR20","IPA","Natural Killer Cell Signaling","Natural Killer Cell Signaling",1.863722658472137,0.5173743071780897,3.0,69.0,74.0,"KRAS,PIK3CB,INPP5B",0.9644572128220502,0.9853938284740591]
["PR35","IPA","Glioblastoma Multiforme Signaling","Glioblastoma Multiforme Signaling",1.8612546174447004,1.0,2.0,8.0,25.0,"CDKN1B,PTEN",0.9669225999194774,0.9877710461810865]
["TR3","IPA","CNTF Signaling","CNTF Signaling",1.8575376678174895,0.5220900633124523,2.0,54.0,34.0,"PIK3CB,RPS6KA5",0.9721955003352674,0.9930161059766991]
["TR4","IPA","NRF2-mediated Oxidative Stress Response","NRF2-mediated Oxidative Stress Response",1.852143369309511,0.5259044487738443,4.0,76.0,125.0,"MAPK1,DNAJC3,TXNRD1,GSTK1",0.981289305824439,1.0]
["TR20","IPA","NGF Signaling","NGF Signaling",1.848070229531291,0.528151508351961,3.0,69.0,75.0,"KRAS,PIK3CB,REL",0.9874691921267382,1.0]
["TR13","IPA","CD28 Signaling in T Helper Cells","CD28 Signaling in T Helper Cells",1.843303703592696,0.5309800653523441,5.0,172.0,85.0,"PPP3CC,ARPC5L,CD247,NFATC2,ZAP70",0.9952853076811001,1.0]
["TR11","IPA","Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses","Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.8405400262583722,0.5309800653523441,11.0,787.0,68.0,"PIK3CG,PRKCQ,MAP2K4,TRAF6,TLR1,TLR2,TLR4,TLR6,TLR8,C5AR1,PTX3",0.9985571360869916,1.0]
["PR6","h.all.v5.0.entrez","HALLMARK_UV_RESPONSE_UP","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UV_RESPONSE_UP",1.8392074356122843,1.0,5.0,78.0,21.0,"PPIF,LYN,STIP1,EIF5,PRKACA",0.699638665442747,0.7552722469538328]
["PR2","IPA","Inhibition of Matrix Metalloproteases","Inhibition of Matrix Metalloproteases",1.8356764200058446,1.0,2.0,12.0,17.0,"MMP1,TIMP3",1.0,1.0]
["TR24","IPA","Dopamine-DARPP32 Feedback in cAMP Signaling","Dopamine-DARPP32 Feedback in cAMP Signaling",1.8341916910838834,0.5309800653523441,4.0,108.0,89.0,"PRKAR2B,CALM3,GUCY1A3,GUCY1B3",1.0,1.0]
["TR2","IPA","Melanoma Signaling","Melanoma Signaling",1.8335645176461355,0.5309800653523441,2.0,61.0,31.0,"HRAS,MAPK1",1.0,1.0]
["TR9","IPA","IL-4 Signaling","IL-4 Signaling",1.8331576720865592,0.5309800653523441,5.0,269.0,55.0,"RRAS,MTOR,SOS1,SOS2,HLA-DQA1",1.0,1.0]
["TR20","IPA","P2Y Purigenic Receptor Signaling Pathway","P2Y Purigenic Receptor Signaling Pathway",1.8326552392555222,0.5309800653523441,3.0,69.0,76.0,"KRAS,PIK3CB,REL",1.0,1.0]
["TR16","h.all.v5.0.entrez","HALLMARK_MITOTIC_SPINDLE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MITOTIC_SPINDLE",1.831381054852949,0.3973159294457965,26.0,1114.0,153.0,"MARCKS,MYH9,TUBGCP3,RACGAP1,KIF15,BIRC5,TOP2A,CDK5RAP2,ARHGAP27,GSN,CENPJ,CENPF,SOS1,DLGAP5,KATNA1,TUBD1,MID1IP1,AURKA,NUSAP1,PXN,CCNB2,BUB1,BCL2L11,NOTCH2,RAPGEF5,CSNK1D",0.699638665442747,0.7552722469538328]
["PR6","IPA","JAK/Stat Signaling","JAK/Stat Signaling",1.8289739674476706,1.0,4.0,78.0,14.0,"MAPK1,MAPK3,PTPN6,PTPN11",1.0,1.0]
["PR23","IPA","IL-10 Signaling","IL-10 Signaling",1.828559897907698,1.0,2.0,10.0,23.0,"IL6,IL1RL2",1.0,1.0]
["TR10","h.all.v5.0.entrez","HALLMARK_INFLAMMATORY_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INFLAMMATORY_RESPONSE",1.8284584480867674,0.3973159294457965,3.0,36.0,147.0,"GCH1,CXCL10,IL15",0.699638665442747,0.7552722469538328]
["PR35","IPA","ILK Signaling","ILK Signaling",1.8281491931410863,1.0,2.0,8.0,26.0,"PTEN,PGF",1.0,1.0]
["PR51","h.all.v5.0.entrez","HALLMARK_KRAS_SIGNALING_UP","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_KRAS_SIGNALING_UP",1.8259196475037145,1.0,2.0,5.0,43.0,"IGFBP3,NRP1",0.699638665442747,0.7552722469538328]
["PR27","h.all.v5.0.entrez","HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY",1.825428164657362,1.0,2.0,30.0,7.0,"CAT,PRDX1",0.699638665442747,0.7552722469538328]
["TR9","IPA","SAPK/JNK Signaling","SAPK/JNK Signaling",1.8240926185488509,0.533341745420345,6.0,269.0,76.0,"RRAS,SOS1,SOS2,TRB,MAP3K9,SH2D2A",1.0,1.0]
["TR24","IPA","HER-2 Signaling in Breast Cancer","HER-2 Signaling in Breast Cancer",1.8239932342634406,0.533341745420345,3.0,108.0,49.0,"EGF,ITGB3,ITGB5",1.0,1.0]
["TR13","IPA","Graft-versus-Host Disease Signaling","Graft-versus-Host Disease Signaling",1.8229798082344413,0.533341745420345,3.0,172.0,31.0,"CD247,GZMB,PRF1",1.0,1.0]
["TR25","IPA","Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes","Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes",1.822212027088395,0.533341745420345,7.0,505.0,53.0,"PLCG1,AKT3,INPP5D,PTEN,PLA2G6,FYN,FCGR1A",1.0,1.0]
["PR29","IPA","IL-17A Signaling in Gastric Cells","IL-17A Signaling in Gastric Cells",1.8162348243420443,1.0,2.0,11.0,19.0,"MAPK12,IL8",1.0,1.0]
["TR28","IPA","Nur77 Signaling in T Lymphocytes","Nur77 Signaling in T Lymphocytes",1.815948916801757,0.5344745482163678,4.0,213.0,46.0,"PPP3CB,PPP3R1,MAP2K5,HLA-DQB1",1.0,1.0]
["TR31","h.all.v5.0.entrez","HALLMARK_G2M_CHECKPOINT","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_G2M_CHECKPOINT",1.814535072648786,0.3973159294457965,8.0,229.0,143.0,"E2F3,LBR,CBX1,ARID4A,HIF1A,RAD23B,NUP98,EWSR1",0.699638665442747,0.7552722469538328]
["TR10","IPA","Communication between Innate and Adaptive Immune Cells","Communication between Innate and Adaptive Immune Cells",1.8100867166285404,0.5344745482163678,2.0,36.0,54.0,"IL15,CXCL10",1.0,1.0]
["PR14","IPA","Extrinsic Prothrombin Activation Pathway","Extrinsic Prothrombin Activation Pathway",1.80744956193134,1.0,4.0,113.0,10.0,"F2,FGA,F5,TFPI",1.0,1.0]
["PR14","h.all.v5.0.entrez","HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION",1.8072467785867274,1.0,13.0,113.0,65.0,"INHBA,TNC,TGFBI,MMP2,TGFBR3,CXCL12,POSTN,SPOCK1,FSTL3,MATN2,LAMA1,IGFBP2,SFRP1",0.699638665442747,0.7552722469538328]
["TR31","IPA","B Cell Receptor Signaling","B Cell Receptor Signaling",1.8068594775994669,0.5344745482163678,7.0,229.0,116.0,"SYNJ1,CHUK,IKBKE,CREB1,CALM1,CAMK2D,MAP3K2",1.0,1.0]
["TR22","IPA","P2Y Purigenic Receptor Signaling Pathway","P2Y Purigenic Receptor Signaling Pathway",1.8054953595251924,0.5344745482163678,20.0,1644.0,76.0,"ATM,KRAS,PIK3C2A,PIK3CA,PRKCA,PLCH2,MRAS,PLCB1,PRKD3,NFKB1,NFKB2,REL,GNAI3,GNB1,GNG3,PRKAG1,PRKAR1B,GNG2,GNB4,P2RY12",1.0,1.0]
["TR22","IPA","Cardiac Hypertrophy Signaling","Cardiac Hypertrophy Signaling",1.8029594455340798,0.5344745482163678,31.0,1644.0,131.0,"ATM,KRAS,PIK3C2A,PIK3CA,MAPK8,PLCH2,MRAS,PLCB1,PPP3CA,ADRA2A,GNAI3,GNB1,GNG3,PRKAG1,PRKAR1B,GNG2,GNB4,MYL5,ROCK1,ROCK2,RHOB,FNBP1,RHOF,RHOT1,MAP2K7,MAP3K1,TGFB1,TGFBR1,MAP3K8,MAP3K9,EIF2B5",1.0,1.0]
["TR6","h.all.v5.0.entrez","HALLMARK_TNFA_SIGNALING_VIA_NFKB","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TNFA_SIGNALING_VIA_NFKB",1.8003003007481775,0.3973159294457965,3.0,35.0,155.0,"TNFAIP6,SAT1,ABCA1",0.699638665442747,0.7552722469538328]
["TR16","IPA","HGF Signaling","HGF Signaling",1.8001561638299974,0.5344745482163678,14.0,1114.0,69.0,"ATM,MAP3K5,PIK3CD,PLCG2,PRKD3,PIK3R6,CRKL,PXN,SOS1,STAT3,CDKN2A,ETS1,MAP3K3,MAP3K13",1.0,1.0]
["TR25","h.all.v5.0.entrez","HALLMARK_MTORC1_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MTORC1_SIGNALING",1.7991234919669559,0.3973159294457965,14.0,505.0,149.0,"NAMPT,SQSTM1,SLC2A3,HK2,DDIT3,QDPR,XBP1,EDEM1,HSPA9,NUP205,UNG,RPA1,EPRS,SRD5A1",0.699638665442747,0.7552722469538328]
["PR6","h.all.v5.0.entrez","HALLMARK_PROTEIN_SECRETION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PROTEIN_SECRETION",1.7982925082068455,1.0,3.0,78.0,8.0,"RPS6KA3,NAPA,MAPK1",0.699638665442747,0.7552722469538328]
["TR20","h.all.v5.0.entrez","HALLMARK_G2M_CHECKPOINT","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_G2M_CHECKPOINT",1.798108603592261,0.3973159294457965,4.0,69.0,143.0,"CDC27,RAD21,YTHDC1,CCNT1",0.699638665442747,0.7552722469538328]
["TR15","IPA","Altered T Cell and B Cell Signaling in Rheumatoid Arthritis","Altered T Cell and B Cell Signaling in Rheumatoid Arthritis",1.7958356732588219,0.5344745482163678,2.0,30.0,66.0,"HLA-DMB,HLA-DRA",1.0,1.0]
["TR24","IPA","Role of NFAT in Regulation of the Immune Response","Role of NFAT in Regulation of the Immune Response",1.7958221145944147,0.5344745482163678,5.0,108.0,139.0,"GNAZ,GNG7,GNG11,TRB,CALM3",1.0,1.0]
["PR31","IPA","Hepatic Fibrosis / Hepatic Stellate Cell Activation","Hepatic Fibrosis / Hepatic Stellate Cell Activation",1.792294479815528,1.0,3.0,9.0,68.0,"TNF,HGF,CTGF",1.0,1.0]
["TR31","IPA","Small Cell Lung Cancer Signaling","Small Cell Lung Cancer Signaling",1.7913642740325832,0.5344745482163678,5.0,229.0,66.0,"CHUK,IKBKE,E2F3,HDAC4,PTGS2",1.0,1.0]
["TR22","IPA","Glioblastoma Multiforme Signaling","Glioblastoma Multiforme Signaling",1.7910132483308687,0.5344745482163678,22.0,1644.0,86.0,"ATM,CDKN1B,KRAS,PIK3C2A,PIK3CA,PLCH2,MRAS,PLCB1,CDK2,APC2,PDGFC,RHOB,FNBP1,RHOF,RHOT1,ITPR2,FZD2,FZD3,FZD6,FZD8,CTNNB1,AXIN1",1.0,1.0]
["TR27","IPA","Calcium-induced T Lymphocyte Apoptosis","Calcium-induced T Lymphocyte Apoptosis",1.7907040382453587,0.5344745482163678,8.0,690.0,49.0,"PPP3R1,ITPR3,HLA-DMA,HLA-DQA1,HLA-DQB1,HLA-DRB1,TRA,HDAC1",1.0,1.0]
["TR27","IPA","Graft-versus-Host Disease Signaling","Graft-versus-Host Disease Signaling",1.790517881269891,0.5344745482163678,6.0,690.0,31.0,"IL18,HLA-DMA,HLA-DQA1,HLA-DQB1,HLA-DRB1,TRA",1.0,1.0]
["TR22","IPA","Breast Cancer Regulation by Stathmin1","Breast Cancer Regulation by Stathmin1",1.7895714017774125,0.5344745482163678,28.0,1644.0,116.0,"ATM,CDKN1B,KRAS,PIK3C2A,PIK3CA,PRKCA,MRAS,PLCB1,PRKD3,TUBB6,PPP1R12A,PPP1CB,PPP2R5A,PPP2R5C,GNAI3,GNB1,GNG3,PRKAG1,PRKAR1B,GNG2,GNB4,CDK2,CDK1,ROCK1,ROCK2,ITPR2,ARHGEF10,RB1CC1",1.0,1.0]
["TR3","IPA","Endometrial Cancer Signaling","Endometrial Cancer Signaling",1.787415588188552,0.5344745482163678,2.0,54.0,37.0,"GSK3B,PIK3CB",1.0,1.0]
["TR3","IPA","ErbB2-ErbB3 Signaling","ErbB2-ErbB3 Signaling",1.787415588188552,0.5344745482163678,2.0,54.0,37.0,"GSK3B,PIK3CB",1.0,1.0]
["PR41","IPA","Protein Ubiquitination Pathway","Protein Ubiquitination Pathway",1.787270028726223,1.0,2.0,12.0,18.0,"MDM2,BIRC3",1.0,1.0]
["TR13","IPA","Autoimmune Thyroid Disease Signaling","Autoimmune Thyroid Disease Signaling",1.7855446949374163,0.5344745482163678,3.0,172.0,32.0,"CD247,GZMB,PRF1",1.0,1.0]
["TR9","IPA","Glucocorticoid Receptor Signaling","Glucocorticoid Receptor Signaling",1.7850111533281803,0.5344745482163678,10.0,269.0,173.0,"RRAS,TNF,CREB1,SOS1,SOS2,TRB,SMAD3,TAF1,CDKN1C,SLPI",1.0,1.0]
["TR26","IPA","Cardiac β-adrenergic Signaling","Cardiac β-adrenergic Signaling",1.7829752783608674,0.5344745482163678,4.0,120.0,83.0,"GNAS,GNG2,AKAP6,AKAP13",1.0,1.0]
["TR14","IPA","Cardiac β-adrenergic Signaling","Cardiac β-adrenergic Signaling",1.7829752783608674,0.5344745482163678,4.0,120.0,83.0,"PPP1R14A,CACNB2,PKIG,AKAP2",1.0,1.0]
["PR6","IPA","Xenobiotic Metabolism Signaling","Xenobiotic Metabolism Signaling",1.7829548381513207,1.0,7.0,78.0,38.0,"PRKCB,PRKCQ,MAPK1,MAPK3,CAMK2A,CAMK2B,CAMK2D",1.0,1.0]
["PR1","h.all.v5.0.entrez","HALLMARK_INFLAMMATORY_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INFLAMMATORY_RESPONSE",1.7808458419055897,1.0,10.0,83.0,61.0,"ICAM1,F3,CXCL10,NAMPT,CXCL11,TNFRSF1B,CX3CL1,CD48,SELE,LTA",0.719443883559157,0.14434917565430178]
["TR22","IPA","HMGB1 Signaling","HMGB1 Signaling",1.7806483008784002,0.5349683455751117,17.0,1644.0,62.0,"ATM,KRAS,PIK3C2A,PIK3CA,MAPK8,MRAS,NFKB1,NFKB2,REL,KAT2B,RHOB,FNBP1,RHOF,RHOT1,MAP2K7,IL8,KAT7",1.0,1.0]
["TR1","h.all.v5.0.entrez","HALLMARK_APOPTOSIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_APOPTOSIS",1.7750841431779207,0.40734710882102737,8.0,271.0,123.0,"ATF3,GADD45B,TAP1,ISG20,CD38,TNFSF10,H1F0,IFITM3",0.720574846559873,0.14434917565430178]
["PR42","IPA","GDNF Family Ligand-Receptor Interactions","GDNF Family Ligand-Receptor Interactions",1.7729509738145395,1.0,2.0,12.0,20.0,"MAPK8,ARTN",1.0,1.0]
["PR42","IPA","Neurotrophin/TRK Signaling","Neurotrophin/TRK Signaling",1.7729509738145395,1.0,2.0,12.0,20.0,"MAPK8,NTRK2",1.0,1.0]
["TR15","IPA","CTLA4 Signaling in Cytotoxic T Lymphocytes","CTLA4 Signaling in Cytotoxic T Lymphocytes",1.7712860831036765,0.5442179787730204,2.0,30.0,68.0,"HLA-DMB,HLA-DRA",1.0,1.0]
["PR34","IPA","Neuroprotective Role of THOP1 in Alzheimer's Disease","Neuroprotective Role of THOP1 in Alzheimer's Disease",1.7708597787177982,1.0,1.0,2.0,9.0,"SERPINA3",1.0,1.0]
["PR52","IPA","Role of Tissue Factor in Cancer","Role of Tissue Factor in Cancer",1.7691864402967834,1.0,2.0,5.0,46.0,"F10,P4HB",1.0,1.0]
["TR8","h.all.v5.0.entrez","HALLMARK_TNFA_SIGNALING_VIA_NFKB","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TNFA_SIGNALING_VIA_NFKB",1.7672889213360128,0.40734710882102737,3.0,36.0,155.0,"CCL2,NFKBIE,CDKN1A",0.7251928581116586,0.7997551440628814]
["TR17","IPA","Aryl Hydrocarbon Receptor Signaling","Aryl Hydrocarbon Receptor Signaling",1.7669506641736976,0.5470710836166586,10.0,531.0,89.0,"BAX,JUN,ALDH5A1,CDK6,ESR1,NFIA,NFIX,RXRA,TGM2,PTGES3",1.0,1.0]
["PR35","IPA","Ovarian Cancer Signaling","Ovarian Cancer Signaling",1.7658551675323744,1.0,2.0,8.0,28.0,"PTEN,PGF",1.0,1.0]
["TR22","IPA","Apoptosis Signaling","Apoptosis Signaling",1.7648172686045107,0.5470710836166586,18.0,1644.0,67.0,"BAD,KRAS,PRKCA,MAPK8,MRAS,NFKB1,NFKB2,REL,CDK1,ROCK1,MAP2K7,FAS,CAPNS1,BIRC2,XIAP,CASP3,BCL2A1,BCL2L11",1.0,1.0]
["TR2","IPA","Protein Ubiquitination Pathway","Protein Ubiquitination Pathway",1.7624801456350754,0.5470710836166586,4.0,61.0,166.0,"DNAJC7,PSMB6,UBR2,USP32",1.0,1.0]
["TR21","h.all.v5.0.entrez","HALLMARK_MTORC1_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MTORC1_SIGNALING",1.761974077528143,0.40734710882102737,35.0,1685.0,149.0,"NAMPT,PDK1,AK4,LDHA,DDIT4,SLC37A4,HMGCS1,TM7SF2,CD9,TMEM97,HPRT1,ELOVL6,SORD,INSIG1,USO1,CTSC,SERP1,TBK1,SLC7A11,CYB5B,ITGB2,PSME3,POLR3G,BCAT1,GMPS,RDH11,MLLT11,GCLC,TCEA1,HSPD1,SYTL2,RPA1,ATP2A2,HMBS,CCT6A",0.725779910271556,0.7997551440628814]
["TR20","IPA","Rac Signaling","Rac Signaling",1.7589294489123837,0.5470710836166586,3.0,69.0,81.0,"KRAS,PIK3CB,REL",1.0,1.0]
["TR20","IPA","iCOS-iCOSL Signaling in T Helper Cells","iCOS-iCOSL Signaling in T Helper Cells",1.7589294489123837,0.5470710836166586,3.0,69.0,81.0,"PIK3CB,PPP3R1,REL",1.0,1.0]
["PR50","IPA","IL-17A Signaling in Airway Cells","IL-17A Signaling in Airway Cells",1.758417787503245,1.0,2.0,9.0,25.0,"CXCL1,CXCL5",1.0,1.0]
["TR2","IPA","CNTF Signaling","CNTF Signaling",1.7570324792165612,0.5470710836166586,2.0,61.0,34.0,"HRAS,MAPK1",1.0,1.0]
["TR17","IPA","Salvage Pathways of Pyrimidine Ribonucleotides","Salvage Pathways of Pyrimidine Ribonucleotides",1.7558252079081256,0.5470710836166586,7.0,531.0,52.0,"MAP2K2,MAP2K3,BRAF,PIM1,CDK6,NME4,APOBEC2",1.0,1.0]
["TR28","IPA","GM-CSF Signaling","GM-CSF Signaling",1.7534964636132573,0.5476719513958176,4.0,213.0,48.0,"PIK3C2A,PPP3CB,PPP3R1,BCL2L1",1.0,1.0]
["PR6","IPA","Aldosterone Signaling in Epithelial Cells","Aldosterone Signaling in Epithelial Cells",1.7522360910012917,1.0,5.0,78.0,22.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PDPK1",1.0,1.0]
["PR49","IPA","Role of Hypercytokinemia/hyperchemokinemia in the Pathogenesis of Influenza","Role of Hypercytokinemia/hyperchemokinemia in the Pathogenesis of Influenza",1.7515831470385654,1.0,2.0,15.0,15.0,"IL12A,IL12B",1.0,1.0]
["TR11","IPA","IL-6 Signaling","IL-6 Signaling",1.7514682253936154,0.5479041588629249,11.0,787.0,70.0,"FOS,PIK3CG,RAF1,MAP2K4,TNFRSF1A,TRAF6,CEBPB,IL1R1,IL1RAP,IL6R,IL1R2",1.0,1.0]
["TR31","IPA","ERK5 Signaling","ERK5 Signaling",1.7438645615628432,0.5508009952389259,4.0,229.0,45.0,"GNA12,GNA13,CREB1,MAP3K2",1.0,1.0]
["TR31","IPA","TR/RXR Activation","TR/RXR Activation",1.7438645615628432,0.5508009952389259,4.0,229.0,45.0,"NCOA2,HIF1A,UCP2,SREBF2",1.0,1.0]
["TR32","IPA","CNTF Signaling","CNTF Signaling",1.7436922080626025,0.5508009952389259,2.0,62.0,34.0,"PIK3CA,RPS6KA3",1.0,1.0]
["PR7","h.all.v5.0.entrez","HALLMARK_UNFOLDED_PROTEIN_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UNFOLDED_PROTEIN_RESPONSE",1.7425371475472609,1.0,2.0,39.0,6.0,"CALR,EIF4A3",0.7468528152760012,0.8206379085511696]
["TR24","h.all.v5.0.entrez","HALLMARK_UV_RESPONSE_DN","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UV_RESPONSE_DN",1.7397841604989501,0.4207621494512683,4.0,108.0,95.0,"ITGB3,MGLL,PRKAR2B,LTBP1",0.7468528152760012,0.8206379085511696]
["TR29","IPA","Wnt/β-catenin Signaling","Wnt/β-catenin Signaling",1.736693374697097,0.5536148873665677,4.0,121.0,85.0,"MYC,LEF1,FZD3,AXIN2",1.0,1.0]
["PR14","IPA","Epithelial Adherens Junction Signaling","Epithelial Adherens Junction Signaling",1.7346567040687437,1.0,6.0,113.0,21.0,"EGFR,MET,FGFR1,NOTCH1,NOTCH3,TGFBR3",1.0,1.0]
["TR20","IPA","Melanoma Signaling","Melanoma Signaling",1.732219085390936,0.5536148873665677,2.0,69.0,31.0,"KRAS,PIK3CB",1.0,1.0]
["PR29","IPA","Hematopoiesis from Pluripotent Stem Cells","Hematopoiesis from Pluripotent Stem Cells",1.7319588117669078,1.0,2.0,11.0,21.0,"IL8,CSF1",1.0,1.0]
["TR20","IPA","Insulin Receptor Signaling","Insulin Receptor Signaling",1.7308982660583054,0.5536148873665677,3.0,69.0,83.0,"KRAS,PIK3CB,INPP5B",1.0,1.0]
["TR20","IPA","Pancreatic Adenocarcinoma Signaling","Pancreatic Adenocarcinoma Signaling",1.7308982660583054,0.5536148873665677,3.0,69.0,83.0,"KRAS,PIK3CB,REL",1.0,1.0]
["TR11","IPA","NF-κB Signaling","NF-κB Signaling",1.7299248544864931,0.5536148873665677,15.0,787.0,108.0,"PIK3CG,PRKCQ,TNFRSF1A,TRAF6,IL1R1,TLR1,TLR2,TLR4,TLR6,TLR8,LCK,IGF2R,IL1R2,IRAK4,SIGIRR",1.0,1.0]
["TR25","IPA","p53 Signaling","p53 Signaling",1.7284931621601882,0.5536148873665677,8.0,505.0,68.0,"ATM,AKT3,PTEN,MAPK14,CCND2,CDK4,TNFRSF10A,DRAM1",1.0,1.0]
["TR2","h.all.v5.0.entrez","HALLMARK_HEME_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HEME_METABOLISM",1.7283769408753877,0.4241065257041222,4.0,61.0,170.0,"NCOA4,SLC22A4,TRAK2,GDE1",0.7583040214627279,0.8320774695601711]
["PR31","IPA","Germ Cell-Sertoli Cell Junction Signaling","Germ Cell-Sertoli Cell Junction Signaling",1.7255853533772598,1.0,2.0,9.0,26.0,"TNF,PAK7",1.0,1.0]
["PR31","IPA","PAK Signaling","PAK Signaling",1.7255853533772598,1.0,2.0,9.0,26.0,"TNF,PAK7",1.0,1.0]
["PR23","IPA","Role of Cytokines in Mediating Communication between Immune Cells","Role of Cytokines in Mediating Communication between Immune Cells",1.7255853533772598,1.0,2.0,10.0,26.0,"IL6,IL3",1.0,1.0]
["TR27","IPA","Autoimmune Thyroid Disease Signaling","Autoimmune Thyroid Disease Signaling",1.7251847593131617,0.5536148873665677,6.0,690.0,32.0,"IL5,HLA-DMA,HLA-DQA1,HLA-DQB1,HLA-DRB1,TRA",1.0,1.0]
["PR9","IPA","PAK Signaling","PAK Signaling",1.7226379354153984,1.0,3.0,24.0,26.0,"ITGA2B,PDGFA,PDGFB",1.0,1.0]
["TR5","IPA","Gα12/13 Signaling","Gα12/13 Signaling",1.7204457451902855,0.5536148873665677,2.0,31.0,70.0,"BTK,MEF2A",1.0,1.0]
["TR24","IPA","Protein Kinase A Signaling","Protein Kinase A Signaling",1.720279881967682,0.5536148873665677,6.0,108.0,199.0,"GNG7,GNG11,PRKAR2B,MYLK,CALM3,PDE5A",1.0,1.0]
["PR6","IPA","CNTF Signaling","CNTF Signaling",1.7185613076140258,1.0,4.0,78.0,15.0,"MAPK1,MAPK3,PTPN11,RPS6KA3",1.0,1.0]
["PR6","IPA","Non-Small Cell Lung Cancer Signaling","Non-Small Cell Lung Cancer Signaling",1.7185613076140258,1.0,4.0,78.0,15.0,"MAPK1,MAPK3,PDPK1,PA2G4",1.0,1.0]
["TR29","IPA","Factors Promoting Cardiogenesis in Vertebrates","Factors Promoting Cardiogenesis in Vertebrates",1.7171460734150688,0.5536148873665677,3.0,121.0,48.0,"PRKCA,LEF1,FZD3",1.0,1.0]
["TR28","IPA","Superpathway of Inositol Phosphate Compounds","Superpathway of Inositol Phosphate Compounds",1.716187882838831,0.5536148873665677,7.0,213.0,130.0,"PIK3C2A,PPP3CB,PPP3R1,PIP5K1B,RNGTT,MTMR9,SSH2",1.0,1.0]
["TR13","IPA","Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells","Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells",1.7146547691288865,0.5536148873665677,3.0,172.0,34.0,"CD247,GZMB,PRF1",1.0,1.0]
["TR15","IPA","Type I Diabetes Mellitus Signaling","Type I Diabetes Mellitus Signaling",1.7131542069209744,0.5536148873665677,2.0,30.0,73.0,"HLA-DMB,HLA-DRA",1.0,1.0]
["TR24","IPA","Colorectal Cancer Metastasis Signaling","Colorectal Cancer Metastasis Signaling",1.7126431471776187,0.5536148873665677,5.0,108.0,146.0,"GNAZ,GNG7,GNG11,PRKAR2B,EGF",1.0,1.0]
["TR2","IPA","Agrin Interactions at Neuromuscular Junction","Agrin Interactions at Neuromuscular Junction",1.7099697738122723,0.5536148873665677,2.0,61.0,36.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","IL-2 Signaling","IL-2 Signaling",1.7099697738122723,0.5536148873665677,2.0,61.0,36.0,"HRAS,MAPK1",1.0,1.0]
["TR24","IPA","Gαq Signaling","Gαq Signaling",1.7099439416852027,0.5536148873665677,4.0,108.0,97.0,"GNAZ,GNG7,GNG11,CALM3",1.0,1.0]
["TR24","IPA","PI3K/AKT Signaling","PI3K/AKT Signaling",1.7099439416852027,0.5536148873665677,4.0,108.0,97.0,"ITGA2B,ITGB3,ITGB5,LIMS1",1.0,1.0]
["PR27","IPA","Mechanisms of Viral Exit from Host Cells","Mechanisms of Viral Exit from Host Cells",1.7081735115448828,1.0,2.0,30.0,8.0,"PRKCD,LMNB1",1.0,1.0]
["TR20","IPA","CD28 Signaling in T Helper Cells","CD28 Signaling in T Helper Cells",1.703640191701855,0.5573716428573895,3.0,69.0,85.0,"PIK3CB,PPP3R1,REL",1.0,1.0]
["TR20","IPA","Estrogen Receptor Signaling","Estrogen Receptor Signaling",1.703640191701855,0.5573716428573895,3.0,69.0,85.0,"KRAS,THRAP3,MED13",1.0,1.0]
["PR4","IPA","Atherosclerosis Signaling","Atherosclerosis Signaling",1.7007028476542914,1.0,6.0,47.0,50.0,"SERPINA1,PLA2G2A,APOB,MMP13,MSR1,TPSB2",1.0,1.0]
["PR51","IPA","Leukocyte Extravasation Signaling","Leukocyte Extravasation Signaling",1.6993554279274445,1.0,2.0,5.0,50.0,"PRKCA,TIMP2",1.0,1.0]
["TR23","h.all.v5.0.entrez","HALLMARK_APOPTOSIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_APOPTOSIS",1.6992422250763508,0.44067162972650825,7.0,227.0,123.0,"GADD45A,SQSTM1,ENO2,SPTAN1,DFFA,CDK2,MADD",0.7905133357726857,0.8640160267594433]
["PR47","h.all.v5.0.entrez","HALLMARK_FATTY_ACID_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_FATTY_ACID_METABOLISM",1.6986990685324548,1.0,2.0,20.0,12.0,"CD36,HPGD",0.7905133357726857,0.8640160267594433]
["PR49","IPA","Differential Regulation of Cytokine Production in Macrophages and T Helper Cells by IL-17A and IL-17F","Differential Regulation of Cytokine Production in Macrophages and T Helper Cells by IL-17A and IL-17F",1.697153761956833,1.0,2.0,15.0,16.0,"IL12A,IL12B",1.0,1.0]
["TR8","IPA","IL-1 Signaling","IL-1 Signaling",1.6966848528113658,0.5641916112888729,2.0,36.0,62.0,"NFKBIE,PRKAR1A",1.0,1.0]
["TR27","h.all.v5.0.entrez","HALLMARK_UNFOLDED_PROTEIN_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UNFOLDED_PROTEIN_RESPONSE",1.696224637979133,0.44067162972650825,11.0,690.0,81.0,"GEMIN4,H2AFX,SLC1A4,NFYA,CALR,NOP14,HYOU1,NOP56,EIF2S1,SDAD1,EXOSC10",0.7905133357726857,0.8640160267594433]
["TR28","IPA","Actin Nucleation by ARP-WASP Complex","Actin Nucleation by ARP-WASP Complex",1.6942448342950818,0.5648558101315548,4.0,213.0,50.0,"ITGAL,WASL,NCK1,NCK2",1.0,1.0]
["PR50","IPA","Role of IL-17A in Arthritis","Role of IL-17A in Arthritis",1.69409150669351,1.0,2.0,9.0,27.0,"CXCL1,CXCL5",1.0,1.0]
["TR19","IPA","Induction of Apoptosis by HIV1","Induction of Apoptosis by HIV1",1.692845933714092,0.5648558101315548,2.0,59.0,38.0,"CYCS,SLC25A13",1.0,1.0]
["TR13","h.all.v5.0.entrez","HALLMARK_IL2_STAT5_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_IL2_STAT5_SIGNALING",1.6884690043956827,0.4408771467600145,7.0,172.0,163.0,"PTCH1,IL2RB,CST7,SYT11,AHNAK,PRKCH,EOMES",0.7962860045428685,0.8692361754389474]
["TR2","IPA","Endometrial Cancer Signaling","Endometrial Cancer Signaling",1.6874925037095962,0.5675294396294481,2.0,61.0,37.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","ErbB2-ErbB3 Signaling","ErbB2-ErbB3 Signaling",1.6874925037095962,0.5675294396294481,2.0,61.0,37.0,"HRAS,MAPK1",1.0,1.0]
["PR35","IPA","HIF1α Signaling","HIF1α Signaling",1.6808682323859163,1.0,2.0,8.0,31.0,"PGF,MMP3",1.0,1.0]
["TR24","IPA","AMPK Signaling","AMPK Signaling",1.6808613296278228,0.5720870351859686,4.0,108.0,99.0,"GNAZ,GNG7,GNG11,PRKAR2B",1.0,1.0]
["TR31","IPA","Hypoxia Signaling in the Cardiovascular System","Hypoxia Signaling in the Cardiovascular System",1.6807410829285065,0.5720870351859686,4.0,229.0,47.0,"CREB1,HIF1A,UBE2D2,UBE2F",1.0,1.0]
["PR10","IPA","Melanocyte Development and Pigmentation Signaling","Melanocyte Development and Pigmentation Signaling",1.6738146835640624,1.0,2.0,13.0,19.0,"PLCG1,BCL2",1.0,1.0]
["PR26","h.all.v5.0.entrez","HALLMARK_HYPOXIA","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HYPOXIA",1.672892083815876,1.0,2.0,7.0,36.0,"BGN,DCN",0.8167673628795818,0.8905025908066532]
["TR1","IPA","Acute Myeloid Leukemia Signaling","Acute Myeloid Leukemia Signaling",1.6707742027540633,0.5815947865296219,5.0,271.0,60.0,"AKT3,REL,JUP,PML,TCF7L1",1.0,0.7398401256477624]
["PR6","IPA","Corticotropin Releasing Hormone Signaling","Corticotropin Releasing Hormone Signaling",1.670746572690893,1.0,5.0,78.0,23.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PRKACA",1.0,1.0]
["PR6","IPA","Integrin Signaling","Integrin Signaling",1.670746572690893,1.0,5.0,78.0,23.0,"MAPK1,MAPK3,SRC,CRK,FYN",1.0,1.0]
["TR2","IPA","EGF Signaling","EGF Signaling",1.665667095117258,0.5815947865296219,2.0,61.0,38.0,"HRAS,MAPK1",1.0,1.0]
["TR20","IPA","Acute Phase Response Signaling","Acute Phase Response Signaling",1.6641234682934556,0.5815947865296219,3.0,69.0,88.0,"KRAS,PIK3CB,REL",1.0,1.0]
["TR3","IPA","Growth Hormone Signaling","Growth Hormone Signaling",1.6639658941355937,0.5815947865296219,2.0,54.0,43.0,"PIK3CB,RPS6KA5",1.0,1.0]
["TR3","IPA","IL-17A Signaling in Airway Cells","IL-17A Signaling in Airway Cells",1.6639658941355937,0.5815947865296219,2.0,54.0,43.0,"GSK3B,PIK3CB",1.0,1.0]
["PR31","IPA","PPAR Signaling","PPAR Signaling",1.6638369660016203,1.0,2.0,9.0,28.0,"TNF,INS",1.0,1.0]
["PR31","IPA","Type II Diabetes Mellitus Signaling","Type II Diabetes Mellitus Signaling",1.6638369660016203,1.0,2.0,9.0,28.0,"TNF,INS",1.0,1.0]
["TR22","IPA","Virus Entry via Endocytic Pathways","Virus Entry via Endocytic Pathways",1.6602451962375688,0.5815947865296219,16.0,1644.0,59.0,"ATM,KRAS,PIK3C2A,PIK3CA,PRKCA,MRAS,PRKD3,ABL1,ACTA2,FLNA,ITGA2,ITGB8,B2M,ITSN1,AP2S1,AP1G2",1.0,1.0]
["TR3","IPA","ILK Signaling","ILK Signaling",1.6598324597856091,0.5815947865296219,3.0,54.0,113.0,"GSK3B,PIK3CB,RPS6KA5",1.0,1.0]
["TR15","IPA","Epithelial Adherens Junction Signaling","Epithelial Adherens Junction Signaling",1.6591606773121197,0.5815947865296219,2.0,30.0,78.0,"SRC,CTNND1",1.0,1.0]
["TR31","IPA","Gαq Signaling","Gαq Signaling",1.6591316266782574,0.5815947865296219,6.0,229.0,97.0,"CHUK,IKBKE,GNA12,GNA13,GNG10,CALM1",1.0,1.0]
["PR41","IPA","Hematopoiesis from Pluripotent Stem Cells","Hematopoiesis from Pluripotent Stem Cells",1.6579784381220368,1.0,2.0,12.0,21.0,"IL7,CD4",1.0,1.0]
["PR7","IPA","Role of JAK1 and JAK3 in γc Cytokine Signaling","Role of JAK1 and JAK3 in γc Cytokine Signaling",1.6571943678774326,1.0,3.0,39.0,17.0,"KRAS,IL4,IL15RA",1.0,1.0]
["TR20","IPA","CNTF Signaling","CNTF Signaling",1.656351788952648,0.5832086467787754,2.0,69.0,34.0,"KRAS,PIK3CB",1.0,1.0]
["PR48","IPA","Aryl Hydrocarbon Receptor Signaling","Aryl Hydrocarbon Receptor Signaling",1.656004300823884,1.0,2.0,11.0,23.0,"CDK2,TGFB1",1.0,1.0]
["PR29","IPA","Corticotropin Releasing Hormone Signaling","Corticotropin Releasing Hormone Signaling",1.656004300823884,1.0,2.0,11.0,23.0,"MAPK12,SHH",1.0,1.0]
["PR35","h.all.v5.0.entrez","HALLMARK_PI3K_AKT_MTOR_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PI3K_AKT_MTOR_SIGNALING",1.654498267423795,1.0,2.0,8.0,32.0,"CDKN1B,PTEN",0.8389173813590541,0.9114406845073287]
["PR43","h.all.v5.0.entrez","HALLMARK_INTERFERON_GAMMA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_GAMMA_RESPONSE",1.650145696589548,1.0,2.0,7.0,37.0,"CFB,CFH",0.8389173813590541,0.9114406845073287]
["TR13","IPA","Allograft Rejection Signaling","Allograft Rejection Signaling",1.6485496915882911,0.5841519102636433,3.0,172.0,36.0,"CD247,GZMB,PRF1",1.0,1.0]
["PR14","h.all.v5.0.entrez","HALLMARK_CHOLESTEROL_HOMEOSTASIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_CHOLESTEROL_HOMEOSTASIS",1.64790730520727,1.0,4.0,113.0,11.0,"JAG1,LGALS3,CXCL16,ALCAM",0.8389173813590541,0.9114406845073287]
["PR45","IPA","Tumoricidal Function of Hepatic Natural Killer Cells","Tumoricidal Function of Hepatic Natural Killer Cells",1.6473591386921325,1.0,1.0,4.0,6.0,"LYVE1",1.0,1.0]
["PR49","IPA","Differential Regulation of Cytokine Production in Intestinal Epithelial Cells by IL-17A and IL-17F","Differential Regulation of Cytokine Production in Intestinal Epithelial Cells by IL-17A and IL-17F",1.6463572904244845,1.0,2.0,15.0,17.0,"IL12A,IL12B",1.0,1.0]
["PR49","IPA","MSP-RON Signaling Pathway","MSP-RON Signaling Pathway",1.6463572904244845,1.0,2.0,15.0,17.0,"IL12A,IL12B",1.0,1.0]
["PR6","IPA","Role of PI3K/AKT Signaling in the Pathogenesis of Influenza","Role of PI3K/AKT Signaling in the Pathogenesis of Influenza",1.6453006211444043,1.0,3.0,78.0,9.0,"MAPK1,MAPK3,CRK",1.0,1.0]
["TR2","IPA","ErbB4 Signaling","ErbB4 Signaling",1.6444591761826624,0.5841519102636433,2.0,61.0,39.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","Estrogen-Dependent Breast Cancer Signaling","Estrogen-Dependent Breast Cancer Signaling",1.6444591761826624,0.5841519102636433,2.0,61.0,39.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","Glioma Invasiveness Signaling","Glioma Invasiveness Signaling",1.6444591761826624,0.5841519102636433,2.0,61.0,39.0,"HRAS,MAPK1",1.0,1.0]
["TR8","IPA","Glucocorticoid Receptor Signaling","Glucocorticoid Receptor Signaling",1.6419920978401346,0.5841519102636433,3.0,36.0,173.0,"NFKBIE,CDKN1A,CCL2",1.0,1.0]
["TR3","IPA","3-phosphoinositide Biosynthesis","3-phosphoinositide Biosynthesis",1.639970697881101,0.5841519102636433,3.0,54.0,115.0,"PIK3CB,NUDT5,PPTC7",1.0,1.0]
["TR31","IPA","D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis","D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis",1.639628126370513,0.5841519102636433,6.0,229.0,98.0,"SYNJ1,DUSP8,PTPN7,PTPN12,MTMR6,NUDT4",1.0,1.0]
["TR31","IPA","D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis","D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis",1.639628126370513,0.5841519102636433,6.0,229.0,98.0,"SYNJ1,DUSP8,PTPN7,PTPN12,MTMR6,NUDT4",1.0,1.0]
["TR26","IPA","RAR Activation","RAR Activation",1.635749586483067,0.5841519102636433,4.0,120.0,92.0,"PRKCH,GNAS,CSNK2A1,ERCC3",1.0,1.0]
["PR23","IPA","Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses","Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.6347331060122912,1.0,2.0,10.0,29.0,"IL6,TLR2",1.0,1.0]
["TR8","IPA","Apoptosis Signaling","Apoptosis Signaling",1.6335620630579282,0.5841519102636433,2.0,36.0,67.0,"NFKBIE,CASP10",1.0,1.0]
["TR11","IPA","Leukocyte Extravasation Signaling","Leukocyte Extravasation Signaling",1.6315474571526565,0.5841519102636433,15.0,787.0,111.0,"PIK3CG,PRKCQ,MAP2K4,CRK,ITGAM,RHOH,MMP25,ICAM3,RASGRP1,TEC,NCF2,BMX,NCF4,CLDN10,ARHGAP9",1.0,1.0]
["TR3","IPA","B Cell Receptor Signaling","B Cell Receptor Signaling",1.6301906088534404,0.5841519102636433,3.0,54.0,116.0,"GSK3B,PIK3CB,TCF3",1.0,1.0]
["PR18","IPA","NRF2-mediated Oxidative Stress Response","NRF2-mediated Oxidative Stress Response",1.6290051201607807,1.0,2.0,9.0,33.0,"MAPK14,AKR1A1",1.0,1.0]
["PR35","IPA","Neuregulin Signaling","Neuregulin Signaling",1.6290051201607807,1.0,2.0,8.0,33.0,"CDKN1B,PTEN",1.0,1.0]
["TR15","IPA","iCOS-iCOSL Signaling in T Helper Cells","iCOS-iCOSL Signaling in T Helper Cells",1.6285312627922859,0.5841519102636433,2.0,30.0,81.0,"HLA-DMB,HLA-DRA",1.0,1.0]
["PR43","h.all.v5.0.entrez","HALLMARK_XENOBIOTIC_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_XENOBIOTIC_METABOLISM",1.6280522977206888,1.0,2.0,7.0,38.0,"CFB,DDC",0.8693794986731845,0.9388617209280894]
["TR22","IPA","AMPK Signaling","AMPK Signaling",1.6280439920947873,0.5841519102636433,24.0,1644.0,99.0,"ATM,PIK3C2A,PIK3CA,MRAS,PPM1B,PPP2R5A,PPP2R5C,EIF4EBP1,PDPK1,ADRA2A,AK4,GNAI3,GNB1,GNG3,LIPE,PFKFB2,PRKAA1,PRKAG1,PRKAR1B,SMARCA4,KAT2B,GNG2,CHRNA10,GNB4",1.0,1.0]
["TR3","IPA","ERK5 Signaling","ERK5 Signaling",1.6269353370215203,0.5841519102636433,2.0,54.0,45.0,"SGK1,RPS6KA5",1.0,1.0]
["TR11","IPA","Signaling by Rho Family GTPases","Signaling by Rho Family GTPases",1.626577805300731,0.5841519102636433,18.0,787.0,141.0,"FOS,PIK3CG,RAF1,MAP2K4,GNAQ,ITGAM,ITGAX,LIMK2,PAK2,IQGAP1,ARPC1A,MYL6B,RHOH,RHOQ,ARHGEF3,CDH2,CDH11,NCF2",1.0,1.0]
["TR7","IPA","Prolactin Signaling","Prolactin Signaling",1.6250484250151729,0.5841519102636433,2.0,42.0,58.0,"STAT3,NMI",1.0,1.0]
["TR2","IPA","Antiproliferative Role of Somatostatin Receptor 2","Antiproliferative Role of Somatostatin Receptor 2",1.6238370213895028,0.5841519102636433,2.0,61.0,40.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","Role of MAPK Signaling in the Pathogenesis of Influenza","Role of MAPK Signaling in the Pathogenesis of Influenza",1.6238370213895028,0.5841519102636433,2.0,61.0,40.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","VEGF Family Ligand-Receptor Interactions","VEGF Family Ligand-Receptor Interactions",1.6238370213895028,0.5841519102636433,2.0,61.0,40.0,"HRAS,MAPK1",1.0,1.0]
["TR8","IPA","Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses","Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.6215513359534037,0.5841519102636433,2.0,36.0,68.0,"NOD1,TICAM1",1.0,1.0]
["PR40","h.all.v5.0.entrez","HALLMARK_UV_RESPONSE_DN","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UV_RESPONSE_DN",1.6206889121150458,1.0,2.0,11.0,24.0,"ERBB2,KIT",0.869704883390957,0.9388617209280894]
["TR31","IPA","PI3K Signaling in B Lymphocytes","PI3K Signaling in B Lymphocytes",1.6204066285649,0.5841519102636433,6.0,229.0,99.0,"CHUK,IKBKE,CREB1,CALM1,CAMK2D,IL4R",1.0,1.0]
["TR13","IPA","PKCθ Signaling in T Lymphocytes","PKCθ Signaling in T Lymphocytes",1.619445036673108,0.5841519102636433,5.0,172.0,97.0,"PPP3CC,CD247,CACNA2D2,NFATC2,ZAP70",1.0,1.0]
["TR16","IPA","Cyclins and Cell Cycle Regulation","Cyclins and Cell Cycle Regulation",1.6194377693612927,0.5841519102636433,12.0,1114.0,59.0,"ATM,PPP2R4,PPP2R5C,CCNB1,CCNB2,CCNA2,ATR,CDKN2A,HDAC5,HDAC7,HDAC8,CDKN2C",1.0,1.0]
["PR6","IPA","Renin-Angiotensin Signaling","Renin-Angiotensin Signaling",1.6187690648077522,1.0,6.0,78.0,32.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PTPN6,PRKACA",1.0,1.0]
["PR6","IPA","IL-2 Signaling","IL-2 Signaling",1.617855711419895,1.0,4.0,78.0,16.0,"MAPK1,MAPK3,PTPN11,CSNK2A1",1.0,1.0]
["PR6","IPA","Leptin Signaling in Obesity","Leptin Signaling in Obesity",1.617855711419895,1.0,4.0,78.0,16.0,"MAPK1,MAPK3,PTPN11,PRKACA",1.0,1.0]
["PR6","IPA","Renal Cell Carcinoma Signaling","Renal Cell Carcinoma Signaling",1.617855711419895,1.0,4.0,78.0,16.0,"MAPK1,MAPK3,PTPN11,CRK",1.0,1.0]
["PR6","IPA","Virus Entry via Endocytic Pathways","Virus Entry via Endocytic Pathways",1.617855711419895,1.0,4.0,78.0,16.0,"PRKCB,PRKCQ,SRC,FYN",1.0,1.0]
["PR6","IPA","fMLP Signaling in Neutrophils","fMLP Signaling in Neutrophils",1.617855711419895,1.0,4.0,78.0,16.0,"PRKCB,PRKCQ,MAPK1,MAPK3",1.0,1.0]
["TR2","IPA","Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis","Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.6164037851958721,0.5862183285796225,4.0,61.0,184.0,"HRAS,MAPK1,TRAF1,LTB",1.0,1.0]
["TR31","IPA","IL-8 Signaling","IL-8 Signaling",1.613264407232581,0.5862183285796225,7.0,229.0,127.0,"CHUK,IKBKE,GNA12,GNA13,GNG10,PTGS2,IRAK3",1.0,1.0]
["TR3","IPA","Role of NFAT in Cardiac Hypertrophy","Role of NFAT in Cardiac Hypertrophy",1.610923327467852,0.5862183285796225,3.0,54.0,118.0,"GSK3B,PIK3CB,SLC8A1",1.0,1.0]
["TR8","h.all.v5.0.entrez","HALLMARK_PI3K_AKT_MTOR_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PI3K_AKT_MTOR_SIGNALING",1.6097310859254397,0.5117515735848462,2.0,36.0,69.0,"CDKN1A,NOD1",0.869704883390957,0.9388617209280894]
["TR20","IPA","IL-2 Signaling","IL-2 Signaling",1.6097310859254395,0.5862183285796225,2.0,69.0,36.0,"KRAS,PIK3CB",1.0,1.0]
["TR3","IPA","IL-17 Signaling","IL-17 Signaling",1.6090877997591015,0.5862183285796225,2.0,54.0,46.0,"GSK3B,PIK3CB",1.0,1.0]
["TR17","h.all.v5.0.entrez","HALLMARK_UV_RESPONSE_UP","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UV_RESPONSE_UP",1.60900414821412,0.5117515735848462,9.0,531.0,81.0,"FURIN,CA2,KCNH2,SLC6A8,CDC34,BSG,APOM,AGO2,GRINA",0.869704883390957,0.9388617209280894]
["TR22","IPA","Protein Kinase A Signaling","Protein Kinase A Signaling",1.607362762268659,0.5862183285796225,43.0,1644.0,199.0,"BAD,PRKCA,YWHAH,PLCH2,PLCB1,PRKD3,PPP1R12A,PPP1CB,PPP3CA,PTPN11,PTPRC,NFKB1,NFKB2,REL,GNAI3,GNB1,GNG3,LIPE,PRKAG1,PRKAR1B,GNG2,GNB4,FLNA,MYL5,PTK2,ROCK1,ROCK2,MAP3K1,ITPR2,TGFB1,SMAD4,TGFBR1,CTNNB1,PDE3B,PDE4D,AKAP13,ADD1,ANAPC13,HHAT,DUSP11,KDELR1,KDELR2,PTPN18",1.0,1.0]
["PR27","h.all.v5.0.entrez","HALLMARK_PEROXISOME","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_PEROXISOME",1.6067004846398947,1.0,2.0,30.0,9.0,"CAT,PRDX1",0.869704883390957,0.9388617209280894]
["PR27","h.all.v5.0.entrez","HALLMARK_SPERMATOGENESIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_SPERMATOGENESIS",1.6067004846398947,1.0,2.0,30.0,9.0,"JAM3,CSNK2A2",0.869704883390957,0.9388617209280894]
["PR23","IPA","Crosstalk between Dendritic Cells and Natural Killer Cells","Crosstalk between Dendritic Cells and Natural Killer Cells",1.6067004846398945,1.0,2.0,10.0,30.0,"IL6,IL3",1.0,1.0]
["PR31","IPA","Type I Diabetes Mellitus Signaling","Type I Diabetes Mellitus Signaling",1.6067004846398945,1.0,2.0,9.0,30.0,"TNF,INS",1.0,1.0]
["PR7","IPA","Mitotic Roles of Polo-Like Kinase","Mitotic Roles of Polo-Like Kinase",1.6065775153461737,1.0,2.0,39.0,7.0,"CHEK2,CCNB1",1.0,1.0]
["PR4","IPA","Signaling by Rho Family GTPases","Signaling by Rho Family GTPases",1.6039071489088395,1.0,4.0,47.0,26.0,"GFAP,PTK2,CDH12,CDH15",1.0,1.0]
["TR2","IPA","Pyridoxal 5'-phosphate Salvage Pathway","Pyridoxal 5'-phosphate Salvage Pathway",1.603771286633491,0.5862183285796225,2.0,61.0,41.0,"MAPK1,HIPK1",1.0,1.0]
["TR2","IPA","Thrombopoietin Signaling","Thrombopoietin Signaling",1.603771286633491,0.5862183285796225,2.0,61.0,41.0,"HRAS,MAPK1",1.0,1.0]
["TR27","IPA","Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells","Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells",1.6032726129609474,0.5862183285796225,6.0,690.0,34.0,"HLA-DMA,HLA-DPA1,HLA-DQA1,HLA-DQB1,HLA-DRB1,TRA",1.0,1.0]
["TR1","IPA","NF-κB Signaling","NF-κB Signaling",1.6026524362827457,0.5862183285796225,7.0,271.0,108.0,"AKT3,IL1RN,MYD88,TNFSF13B,TLR7,TNFAIP3,EIF2AK2",1.0,0.8113923797809931]
["TR11","IPA","T Cell Receptor Signaling","T Cell Receptor Signaling",1.601068704849505,0.5862183285796225,12.0,787.0,83.0,"CBL,FOS,PIK3CG,PRKCQ,RAF1,MAP2K4,LCK,LAT,CD8A,RASGRP1,TEC,BMX",1.0,1.0]
["PR8","IPA","Protein Ubiquitination Pathway","Protein Ubiquitination Pathway",1.598764572135927,1.0,2.0,15.0,18.0,"HSPA8,PSMA6",1.0,1.0]
["TR9","IPA","Dendritic Cell Maturation","Dendritic Cell Maturation",1.5987273197668066,0.5862183285796225,7.0,269.0,109.0,"PDIA3,TNF,CREB1,HLA-DQA1,TRB,IL12B,CD1A",1.0,1.0]
["TR8","IPA","Hepatic Cholestasis","Hepatic Cholestasis",1.5980957843720363,0.5862183285796225,2.0,36.0,70.0,"NFKBIE,PRKAR1A",1.0,1.0]
["TR8","IPA","Renin-Angiotensin Signaling","Renin-Angiotensin Signaling",1.5980957843720363,0.5862183285796225,2.0,36.0,70.0,"PRKAR1A,CCL2",1.0,1.0]
["PR6","IPA","Regulation of eIF4 and p70S6K Signaling","Regulation of eIF4 and p70S6K Signaling",1.5942172838657778,1.0,5.0,78.0,24.0,"MAPK1,MAPK3,PDPK1,EIF4G2,RPS27A",1.0,1.0]
["TR17","IPA","Toll-like Receptor Signaling","Toll-like Receptor Signaling",1.5927317928547688,0.589468196655492,6.0,531.0,44.0,"JUN,TRAF1,MAP2K3,ECSIT,TOLLIP,TICAM2",1.0,1.0]
["TR3","IPA","Hypoxia Signaling in the Cardiovascular System","Hypoxia Signaling in the Cardiovascular System",1.5916595222678784,0.589468196655492,2.0,54.0,47.0,"UBE2S,UBE2F",1.0,1.0]
["TR15","IPA","CD28 Signaling in T Helper Cells","CD28 Signaling in T Helper Cells",1.5895531995575358,0.589468196655492,2.0,30.0,85.0,"HLA-DMB,HLA-DRA",1.0,1.0]
["TR15","IPA","Wnt/β-catenin Signaling","Wnt/β-catenin Signaling",1.5895531995575358,0.589468196655492,2.0,30.0,85.0,"SRC,FZD1",1.0,1.0]
["PR7","IPA","NF-κB Activation by Viruses","NF-κB Activation by Viruses",1.589096483382688,1.0,3.0,39.0,18.0,"KRAS,PRKCG,TNFRSF14",1.0,1.0]
["TR20","IPA","Endometrial Cancer Signaling","Endometrial Cancer Signaling",1.587474468255718,0.589468196655492,2.0,69.0,37.0,"KRAS,PIK3CB",1.0,1.0]
["TR20","IPA","ErbB2-ErbB3 Signaling","ErbB2-ErbB3 Signaling",1.587474468255718,0.589468196655492,2.0,69.0,37.0,"KRAS,PIK3CB",1.0,1.0]
["PR48","IPA","Factors Promoting Cardiogenesis in Vertebrates","Factors Promoting Cardiogenesis in Vertebrates",1.5869497801717787,1.0,2.0,11.0,25.0,"CDK2,TGFB1",1.0,1.0]
["PR3","IPA","IL-10 Signaling","IL-10 Signaling",1.5825662165260823,1.0,2.0,12.0,23.0,"MAPK11,LBP",1.0,1.0]
["PR3","IPA","LPS-stimulated MAPK Signaling","LPS-stimulated MAPK Signaling",1.5825662165260823,1.0,2.0,12.0,23.0,"MAPK11,LBP",1.0,1.0]
["TR30","IPA","Role of CHK Proteins in Cell Cycle Checkpoint Control","Role of CHK Proteins in Cell Cycle Checkpoint Control",1.5806720864556945,0.590549486225501,2.0,66.0,39.0,"PPP2R5D,MRE11A",1.0,1.0]
["PR33","ADAMs","MMP9","MMP9",1.5804412880376535,0.9030128777453612,2.0,8.0,35.0,"HAPLN1,MBL2",0.9008903058488887,1.0]
["PR35","IPA","Pancreatic Adenocarcinoma Signaling","Pancreatic Adenocarcinoma Signaling",1.5804412880376535,1.0,2.0,8.0,35.0,"CDKN1B,PGF",1.0,1.0]
["TR15","IPA","Glioblastoma Multiforme Signaling","Glioblastoma Multiforme Signaling",1.5801199843501401,0.590549486225501,2.0,30.0,86.0,"SRC,FZD1",1.0,1.0]
["TR15","IPA","Ovarian Cancer Signaling","Ovarian Cancer Signaling",1.5801199843501401,0.590549486225501,2.0,30.0,86.0,"SRC,FZD1",1.0,1.0]
["PR5","h.all.v5.0.entrez","HALLMARK_MYOGENESIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MYOGENESIS",1.57966761613576,1.0,2.0,9.0,31.0,"FABP3,MB",0.8977183637548053,0.9799610600710077]
["PR23","IPA","Altered T Cell and B Cell Signaling in Rheumatoid Arthritis","Altered T Cell and B Cell Signaling in Rheumatoid Arthritis",1.57966761613576,1.0,2.0,10.0,31.0,"IL6,TLR2",1.0,1.0]
["TR19","IPA","Leukocyte Extravasation Signaling","Leukocyte Extravasation Signaling",1.5795181442588757,0.590549486225501,3.0,59.0,111.0,"WASL,NOX3,ARHGAP5",1.0,1.0]
["TR10","h.all.v5.0.entrez","HALLMARK_INTERFERON_GAMMA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_GAMMA_RESPONSE",1.5787512476906145,0.5389862045638673,3.0,36.0,183.0,"GCH1,CXCL10,IL15",0.8977183637548053,0.9799610600710077]
["TR13","IPA","Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes","Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes",1.5782633210301429,0.590549486225501,4.0,172.0,67.0,"PPP3CC,CD247,NFATC2,ZAP70",1.0,1.0]
["TR17","IPA","14-3-3-mediated Signaling","14-3-3-mediated Signaling",1.5780971923073546,0.590549486225501,8.0,531.0,69.0,"BAX,JUN,MAP2K2,SNCA,STK11,TUBB2A,TUBB3,TUBB4B",1.0,1.0]
["TR22","IPA","Gα12/13 Signaling","Gα12/13 Signaling",1.5768605522192543,0.590549486225501,18.0,1644.0,70.0,"ATM,KRAS,PIK3C2A,PIK3CA,MAPK8,MRAS,RASA1,NFKB1,NFKB2,REL,MYL5,PTK2,ROCK1,ROCK2,VAV3,MAP2K7,MAP3K1,CTNNB1",1.0,1.0]
["TR8","IPA","Prostate Cancer Signaling","Prostate Cancer Signaling",1.5753590839112388,0.590549486225501,2.0,36.0,72.0,"NFKBIE,CDKN1A",1.0,1.0]
["TR3","IPA","Factors Promoting Cardiogenesis in Vertebrates","Factors Promoting Cardiogenesis in Vertebrates",1.574632631357896,0.590549486225501,2.0,54.0,48.0,"GSK3B,TCF3",1.0,1.0]
["PR15","h.all.v5.0.entrez","HALLMARK_ESTROGEN_RESPONSE_LATE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ESTROGEN_RESPONSE_LATE",1.5740426509767154,1.0,2.0,10.0,28.0,"AGR2,CPE",0.8977183637548053,0.9799610600710077]
["TR22","IPA","NGF Signaling","NGF Signaling",1.572731970445676,0.5913100604913354,19.0,1644.0,75.0,"ATM,KRAS,PIK3C2A,PIK3CA,MAPK8,MRAS,PTPN11,NFKB1,NFKB2,REL,PDPK1,ROCK1,TRIO,ROCK2,MAP3K1,MAP3K8,MAP3K9,RPS6KA3,SMPD1",1.0,1.0]
["TR1","IPA","Growth Hormone Signaling","Growth Hormone Signaling",1.571441563438985,0.5913100604913354,4.0,271.0,43.0,"PRKCE,STAT1,JAK2,SOCS1",1.0,0.8205647543518501]
["TR23","IPA","SAPK/JNK Signaling","SAPK/JNK Signaling",1.567819670684013,0.5927833033153665,5.0,227.0,76.0,"GADD45A,NFATC1,NFATC3,MAP3K13,MINK1",1.0,1.0]
["TR1","h.all.v5.0.entrez","HALLMARK_ALLOGRAFT_REJECTION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ALLOGRAFT_REJECTION",1.5677881285948045,0.5389862045638673,9.0,271.0,160.0,"RIPK2,TAP1,STAT1,SOCS1,CCR1,JAK2,IRF7,FCGR2B,TAP2",0.8977183637548053,0.1983782650005451]
["TR6","h.all.v5.0.entrez","HALLMARK_ANDROGEN_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ANDROGEN_RESPONSE",1.5652963863989626,0.5389862045638673,2.0,35.0,75.0,"SAT1,UBE2I",0.8977183637548053,0.9799610600710077]
["TR16","IPA","CNTF Signaling","CNTF Signaling",1.5649987579996985,0.5927833033153665,8.0,1114.0,34.0,"ATM,PIK3CD,PIK3R6,SOS1,STAT3,JAK1,RPS6KA2,TYK2",1.0,1.0]
["TR31","IPA","Superpathway of Inositol Phosphate Compounds","Superpathway of Inositol Phosphate Compounds",1.5647449462110103,0.5927833033153665,7.0,229.0,130.0,"SYNJ1,DUSP8,PTPN7,PTPN12,MTMR6,NUDT4,TMEM55A",1.0,1.0]
["PR35","IPA","Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis","Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.5626771195681535,1.0,3.0,8.0,94.0,"FGF2,PGF,MMP3",1.0,1.0]
["TR26","IPA","Gαq Signaling","Gαq Signaling",1.561579429774316,0.5927833033153665,4.0,120.0,97.0,"PRKCH,GNAS,GNG2,NAPEPLD",1.0,1.0]
["TR14","IPA","PKCθ Signaling in T Lymphocytes","PKCθ Signaling in T Lymphocytes",1.561579429774316,0.5927833033153665,4.0,120.0,97.0,"VAV2,HLA-DOA,HLA-DOB,CACNB2",1.0,1.0]
["PR25","IPA","Pyridoxal 5'-phosphate Salvage Pathway","Pyridoxal 5'-phosphate Salvage Pathway",1.5598902953005136,1.0,3.0,40.0,18.0,"PAK3,CDK5,CDK8",1.0,1.0]
["TR3","IPA","HER-2 Signaling in Breast Cancer","HER-2 Signaling in Breast Cancer",1.5579903715431558,0.5927833033153665,2.0,54.0,49.0,"GSK3B,PIK3CB",1.0,1.0]
["PR1","h.all.v5.0.entrez","HALLMARK_INTERFERON_ALPHA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_ALPHA_RESPONSE",1.5578231175562833,1.0,3.0,83.0,9.0,"CXCL10,CXCL11,B2M",0.8977183637548053,0.1983782650005451]
["PR18","h.all.v5.0.entrez","HALLMARK_HYPOXIA","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HYPOXIA",1.5572778131251432,1.0,2.0,9.0,36.0,"GPI,NAGK",0.8977183637548053,0.9799610600710077]
["PR35","h.all.v5.0.entrez","HALLMARK_HYPOXIA","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HYPOXIA",1.5572778131251432,1.0,2.0,8.0,36.0,"PGF,CDKN1B",0.8977183637548053,0.9799610600710077]
["TR22","IPA","Endometrial Cancer Signaling","Endometrial Cancer Signaling",1.5572190886807231,0.5927833033153665,11.0,1644.0,37.0,"ATM,BAD,KRAS,PIK3C2A,PIK3CA,MRAS,PDPK1,APC2,CTNNB1,AXIN1,ILK",1.0,1.0]
["TR13","h.all.v5.0.entrez","HALLMARK_TGF_BETA_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TGF_BETA_SIGNALING",1.557216731801644,0.5405276063453229,3.0,172.0,39.0,"ID2,SMAD7,SLC20A1",0.8977183637548053,0.9799610600710077]
["PR6","IPA","Endothelin-1 Signaling","Endothelin-1 Signaling",1.556998551181491,1.0,6.0,78.0,33.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC,PRDX6",1.0,1.0]
["PR6","IPA","ErbB Signaling","ErbB Signaling",1.556998551181491,1.0,6.0,78.0,33.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PDPK1,AREG",1.0,1.0]
["PR11","IPA","IL-8 Signaling","IL-8 Signaling",1.5566543488735047,1.0,4.0,30.0,42.0,"MAP2K1,MMP9,AZU1,MPO",1.0,1.0]
["PR6","IPA","Ephrin Receptor Signaling","Ephrin Receptor Signaling",1.5559380285737001,1.0,7.0,78.0,42.0,"MAPK1,MAPK3,SRC,ACP1,PTPN11,CRK,FYN",1.0,1.0]
["TR3","IPA","ERK/MAPK Signaling","ERK/MAPK Signaling",1.5553480698917033,0.5927833033153665,3.0,54.0,124.0,"PIK3CB,RPS6KA5,KSR1",1.0,1.0]
["TR20","IPA","Gαq Signaling","Gαq Signaling",1.5544462914112798,0.5927833033153665,3.0,69.0,97.0,"PIK3CB,PPP3R1,REL",1.0,1.0]
["PR20","IPA","IL-17A Signaling in Gastric Cells","IL-17A Signaling in Gastric Cells",1.5540182945231695,1.0,2.0,15.0,19.0,"CCL5,IL17RA",1.0,1.0]
["PR50","IPA","IL-17 Signaling","IL-17 Signaling",1.5535699425529925,1.0,2.0,9.0,32.0,"CXCL1,CXCL5",1.0,1.0]
["PR31","IPA","Renin-Angiotensin Signaling","Renin-Angiotensin Signaling",1.5535699425529925,1.0,2.0,9.0,32.0,"TNF,PAK7",1.0,1.0]
["TR8","IPA","Relaxin Signaling","Relaxin Signaling",1.5533015117043014,0.5927833033153665,2.0,36.0,74.0,"NFKBIE,PRKAR1A",1.0,1.0]
["TR32","IPA","Growth Hormone Signaling","Growth Hormone Signaling",1.5521101837263394,0.5927833033153665,2.0,62.0,43.0,"PIK3CA,RPS6KA3",1.0,1.0]
["PR34","IPA","FXR/RXR Activation","FXR/RXR Activation",1.5502501012169945,1.0,1.0,2.0,15.0,"APOE",1.0,1.0]
["PR8","pSS GWAS","nearby genes+cis eGenes+trans eGenes","nearby genes+cis eGenes+trans eGenes",1.5502501012169878,1.0,1.0,15.0,2.0,"ERBB4",1.0,1.0]
["TR16","IPA","Hypoxia Signaling in the Cardiovascular System","Hypoxia Signaling in the Cardiovascular System",1.549419551900972,0.5927833033153665,10.0,1114.0,47.0,"ATM,CREBBP,CSNK1D,VEGFA,UBE2E1,UBE2H,UBE2J1,UBE2R2,UBE2Q1,HIF1AN",1.0,1.0]
["TR9","IPA","GDNF Family Ligand-Receptor Interactions","GDNF Family Ligand-Receptor Interactions",1.5491855426590642,0.5927833033153665,4.0,269.0,44.0,"RRAS,CREB1,SOS1,SOS2",1.0,1.0]
["TR2","IPA","GDNF Family Ligand-Receptor Interactions","GDNF Family Ligand-Receptor Interactions",1.5466501888158615,0.5927833033153665,2.0,61.0,44.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","Toll-like Receptor Signaling","Toll-like Receptor Signaling",1.5466501888158615,0.5927833033153665,2.0,61.0,44.0,"MAPK1,TRAF1",1.0,1.0]
["PR4","h.all.v5.0.entrez","HALLMARK_COMPLEMENT","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_COMPLEMENT",1.54611979232028,1.0,7.0,47.0,69.0,"CASP3,SERPINA1,C1S,MMP13,FCN1,CASP10,MMP12",0.9062424820658955,0.9872635357067148]
["PR26","h.all.v5.0.entrez","HALLMARK_APOPTOSIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_APOPTOSIS",1.5455592863184875,1.0,2.0,7.0,42.0,"BGN,DCN",0.9062424820658955,0.9872635357067148]
["TR20","IPA","ErbB4 Signaling","ErbB4 Signaling",1.5448817463058742,0.5927833033153665,2.0,69.0,39.0,"KRAS,PIK3CB",1.0,1.0]
["TR20","IPA","Glioma Invasiveness Signaling","Glioma Invasiveness Signaling",1.5448817463058742,0.5927833033153665,2.0,69.0,39.0,"KRAS,PIK3CB",1.0,1.0]
["TR20","IPA","Mitotic Roles of Polo-Like Kinase","Mitotic Roles of Polo-Like Kinase",1.5448817463058742,0.5927833033153665,2.0,69.0,39.0,"CDC27,RAD21",1.0,1.0]
["TR20","IPA","Myc Mediated Apoptosis Signaling","Myc Mediated Apoptosis Signaling",1.5448817463058742,0.5927833033153665,2.0,69.0,39.0,"KRAS,PIK3CB",1.0,1.0]
["TR20","IPA","Role of IL-17A in Arthritis","Role of IL-17A in Arthritis",1.5448817463058742,0.5927833033153665,2.0,69.0,39.0,"PIK3CB,REL",1.0,1.0]
["TR28","IPA","Assembly of RNA Polymerase II Complex","Assembly of RNA Polymerase II Complex",1.543048995345974,0.5929584618520761,3.0,213.0,32.0,"GTF2F1,GTF2H3,DR1",1.0,1.0]
["TR9","IPA","Acute Phase Response Signaling","Acute Phase Response Signaling",1.5422858488621736,0.5929584618520761,6.0,269.0,88.0,"RRAS,TNF,MTOR,SOS1,SOS2,HMOX1",1.0,1.0]
["TR19","IPA","Nur77 Signaling in T Lymphocytes","Nur77 Signaling in T Lymphocytes",1.5376401342140953,0.5966541740900444,2.0,59.0,46.0,"CYCS,CABIN1",1.0,1.0]
["TR11","h.all.v5.0.entrez","HALLMARK_WNT_BETA_CATENIN_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_WNT_BETA_CATENIN_SIGNALING",1.5373794756108037,0.5570853697281004,6.0,787.0,31.0,"RBPJ,NOTCH1,MAML1,NUMB,FRAT1,HEY1",0.9155801215438689,0.9964532952577038]
["TR1","IPA","G Beta Gamma Signaling","G Beta Gamma Signaling",1.5371337890450736,0.5966541740900444,5.0,271.0,65.0,"PRKCE,AKT3,GNG5,CACNA1A,CACNA2D3",1.0,0.8386814733874133]
["TR22","IPA","Mouse Embryonic Stem Cell Pluripotency","Mouse Embryonic Stem Cell Pluripotency",1.529555314890338,0.6017743047980829,16.0,1644.0,61.0,"ATM,KRAS,PIK3C2A,PIK3CA,MRAS,PTPN11,APC2,XIAP,SMAD4,FZD2,FZD3,FZD6,FZD8,SMAD9,CTNNB1,AXIN1",1.0,1.0]
["TR3","IPA","Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis","Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.5287385491396097,0.6017743047980829,3.0,54.0,127.0,"GSK3B,PIK3CB,TCF3",1.0,1.0]
["TR2","IPA","ERK5 Signaling","ERK5 Signaling",1.528556736911668,0.6017743047980829,2.0,61.0,45.0,"HRAS,ELK4",1.0,1.0]
["TR2","IPA","Neurotrophin/TRK Signaling","Neurotrophin/TRK Signaling",1.528556736911668,0.6017743047980829,2.0,61.0,45.0,"HRAS,MAPK1",1.0,1.0]
["TR20","IPA","Antiproliferative Role of Somatostatin Receptor 2","Antiproliferative Role of Somatostatin Receptor 2",1.524479543947752,0.604085038313884,2.0,69.0,40.0,"KRAS,PIK3CB",1.0,1.0]
["TR20","IPA","VEGF Family Ligand-Receptor Interactions","VEGF Family Ligand-Receptor Interactions",1.524479543947752,0.604085038313884,2.0,69.0,40.0,"KRAS,PIK3CB",1.0,1.0]
["PR29","IPA","Role of IL-17A in Arthritis","Role of IL-17A in Arthritis",1.5237095820487552,1.0,2.0,11.0,27.0,"MAPK12,IL8",1.0,1.0]
["PR6","h.all.v5.0.entrez","HALLMARK_MTORC1_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MTORC1_SIGNALING",1.5221972945124904,1.0,5.0,78.0,25.0,"TPI1,GAPDH,PPIA,UFM1,STIP1",0.9259979336298368,1.0]
["PR6","IPA","Cholecystokinin/Gastrin-mediated Signaling","Cholecystokinin/Gastrin-mediated Signaling",1.5221972945124904,1.0,5.0,78.0,25.0,"PRKCB,PRKCQ,MAPK1,MAPK3,SRC",1.0,1.0]
["TR26","IPA","Protein Kinase A Signaling","Protein Kinase A Signaling",1.5218272169360312,0.6061066344819296,6.0,120.0,199.0,"PRKCH,GNAS,GNG2,AKAP6,AKAP13,PTPRG",1.0,1.0]
["PR14","h.all.v5.0.entrez","HALLMARK_NOTCH_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_NOTCH_SIGNALING",1.5208838469421315,1.0,3.0,113.0,7.0,"JAG1,NOTCH1,NOTCH3",0.9259979336298368,1.0]
["TR19","h.all.v5.0.entrez","HALLMARK_GLYCOLYSIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_GLYCOLYSIS",1.5208284098389708,0.5699571943562596,3.0,59.0,117.0,"PPIA,SLC35A3,SLC25A13",0.9259979336298368,1.0]
["TR25","IPA","Systemic Lupus Erythematosus Signaling","Systemic Lupus Erythematosus Signaling",1.5181663201836209,0.6082529201090713,11.0,505.0,117.0,"ATM,PLCG1,AKT3,INPP5D,PTPRC,FCGR1A,FCGR1B,SNRPN,SNRNP200,LSM4,LSM11",1.0,1.0]
["TR9","IPA","Neurotrophin/TRK Signaling","Neurotrophin/TRK Signaling",1.5175643042664222,0.6082529201090713,4.0,269.0,45.0,"RRAS,CREB1,SOS1,SOS2",1.0,1.0]
["PR15","IPA","Type I Diabetes Mellitus Signaling","Type I Diabetes Mellitus Signaling",1.517449159711478,1.0,2.0,10.0,30.0,"MAPK9,CPE",1.0,1.0]
["PR9","ADAMs","ADAMs","ADAMs",1.5172713511755627,0.9030128777453612,3.0,24.0,31.0,"APP,GP1BA,SELL",0.9116956938775281,1.0]
["TR22","IPA","Rac Signaling","Rac Signaling",1.5164972493891629,0.6082529201090713,20.0,1644.0,81.0,"ATM,KRAS,PIK3C2A,PIK3CA,MAPK8,MRAS,PIP4K2B,PIP5K1C,PIKFYVE,NFKB1,NFKB2,REL,ITGA2,ITGB8,PTK2,ITGA10,ACTR2,IQGAP2,MAP2K7,MAP3K1",1.0,1.0]
["PR10","IPA","IL-15 Signaling","IL-15 Signaling",1.5157525501053135,1.0,2.0,13.0,23.0,"PLCG1,BCL2",1.0,1.0]
["TR32","IPA","ERK5 Signaling","ERK5 Signaling",1.5155195373511043,0.6082529201090713,2.0,62.0,45.0,"RPS6KA3,MEF2A",1.0,1.0]
["PR16","h.all.v5.0.entrez","HALLMARK_TGF_BETA_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TGF_BETA_SIGNALING",1.514291844126955,1.0,3.0,98.0,8.0,"MAP3K7,NOG,BCAR3",0.9259979336298368,1.0]
["PR16","h.all.v5.0.entrez","HALLMARK_BILE_ACID_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_BILE_ACID_METABOLISM",1.514291844126955,1.0,3.0,98.0,8.0,"PRDX5,BCAR3,BMP6",0.9259979336298368,1.0]
["PR6","IPA","Endometrial Cancer Signaling","Endometrial Cancer Signaling",1.5134198129580754,1.0,3.0,78.0,10.0,"MAPK1,MAPK3,PDPK1",1.0,1.0]
["TR2","IPA","IL-15 Signaling","IL-15 Signaling",1.5109014586698313,0.6090660139717405,2.0,61.0,46.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","IL-17 Signaling","IL-17 Signaling",1.5109014586698313,0.6090660139717405,2.0,61.0,46.0,"HRAS,MAPK1",1.0,1.0]
["TR3","IPA","FLT3 Signaling in Hematopoietic Progenitor Cells","FLT3 Signaling in Hematopoietic Progenitor Cells",1.5102187348110987,0.6090660139717405,2.0,54.0,52.0,"PIK3CB,RPS6KA5",1.0,1.0]
["TR3","IPA","Melanocyte Development and Pigmentation Signaling","Melanocyte Development and Pigmentation Signaling",1.5102187348110987,0.6090660139717405,2.0,54.0,52.0,"PIK3CB,RPS6KA5",1.0,1.0]
["TR4","h.all.v5.0.entrez","HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY",1.5098222049723282,0.5758608814593917,2.0,76.0,37.0,"ATOX1,TXNRD1",0.927970939397807,1.0]
["TR15","IPA","Germ Cell-Sertoli Cell Junction Signaling","Germ Cell-Sertoli Cell Junction Signaling",1.508709305872561,0.6095391566616468,2.0,30.0,94.0,"SRC,CTNND1",1.0,1.0]
["TR26","IPA","Androgen Signaling","Androgen Signaling",1.5056732218670537,0.6098954521377226,4.0,120.0,101.0,"PRKCH,GNAS,GNG2,ERCC3",1.0,1.0]
["TR20","IPA","FcγRIIB Signaling in B Lymphocytes","FcγRIIB Signaling in B Lymphocytes",1.504633527586141,0.6098954521377226,2.0,69.0,41.0,"KRAS,PIK3CB",1.0,1.0]
["TR20","IPA","Thrombopoietin Signaling","Thrombopoietin Signaling",1.504633527586141,0.6098954521377226,2.0,69.0,41.0,"KRAS,PIK3CB",1.0,1.0]
["PR31","IPA","Hepatic Cholestasis","Hepatic Cholestasis",1.5039515141635862,1.0,2.0,9.0,34.0,"TNF,INS",1.0,1.0]
["PR23","IPA","Hepatic Cholestasis","Hepatic Cholestasis",1.5039515141635862,1.0,2.0,10.0,34.0,"IL6,IL1RL2",1.0,1.0]
["TR3","IPA","Superpathway of Inositol Phosphate Compounds","Superpathway of Inositol Phosphate Compounds",1.5028648254436123,0.6098954521377226,3.0,54.0,130.0,"PIK3CB,NUDT5,PPTC7",1.0,1.0]
["TR29","IPA","Prolactin Signaling","Prolactin Signaling",1.5026415854656512,0.6098954521377226,3.0,121.0,58.0,"PRKCA,SOCS3,MYC",1.0,1.0]
["TR9","IPA","Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes","Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes",1.4994875260088414,0.612711383482455,5.0,269.0,67.0,"RRAS,SOS1,SOS2,TRB,SMAD3",1.0,1.0]
["PR25","h.all.v5.0.entrez","HALLMARK_G2M_CHECKPOINT","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_G2M_CHECKPOINT",1.4966278334650909,1.0,3.0,40.0,19.0,"AURKB,CHEK1,SYNCRIP",0.9488819245034105,1.0]
["PR30","IPA","Pyridoxal 5'-phosphate Salvage Pathway","Pyridoxal 5'-phosphate Salvage Pathway",1.4951607734960137,1.0,2.0,17.0,18.0,"PIM1,PLK1",1.0,1.0]
["TR3","IPA","Reelin Signaling in Neurons","Reelin Signaling in Neurons",1.494966787362951,0.6128528374110216,2.0,54.0,53.0,"GSK3B,PIK3CB",1.0,1.0]
["TR2","IPA","BMP signaling pathway","BMP signaling pathway",1.4936652612559982,0.6128528374110216,2.0,61.0,47.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","CD40 Signaling","CD40 Signaling",1.4936652612559982,0.6128528374110216,2.0,61.0,47.0,"MAPK1,TRAF1",1.0,1.0]
["TR2","IPA","Chemokine Signaling","Chemokine Signaling",1.4936652612559982,0.6128528374110216,2.0,61.0,47.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","Role of JAK1 and JAK3 in γc Cytokine Signaling","Role of JAK1 and JAK3 in γc Cytokine Signaling",1.4936652612559982,0.6128528374110216,2.0,61.0,47.0,"HRAS,MAPK1",1.0,1.0]
["TR15","IPA","Molecular Mechanisms of Cancer","Molecular Mechanisms of Cancer",1.4882711544948082,0.6188920398445267,3.0,30.0,239.0,"SRC,FZD1,CTNND1",1.0,1.0]
["TR7","h.all.v5.0.entrez","HALLMARK_HEME_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HEME_METABOLISM",1.4868834030002824,0.5981667516345385,3.0,42.0,170.0,"ICAM4,PDZK1IP1,HTATIP2",0.9583814406393489,1.0]
["PR51","h.all.v5.0.entrez","HALLMARK_NOTCH_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_NOTCH_SIGNALING",1.4853527523600678,1.0,1.0,5.0,7.0,"PRKCA",0.9583814406393489,1.0]
["TR2","IPA","Systemic Lupus Erythematosus Signaling","Systemic Lupus Erythematosus Signaling",1.4837565139107791,0.6222904805936208,3.0,61.0,117.0,"HRAS,MAPK1,LSM2",1.0,1.0]
["TR15","IPA","PKCθ Signaling in T Lymphocytes","PKCθ Signaling in T Lymphocytes",1.4836309383390112,0.6222904805936208,2.0,30.0,97.0,"HLA-DMB,HLA-DRA",1.0,1.0]
["TR5","IPA","Clathrin-mediated Endocytosis Signaling","Clathrin-mediated Endocytosis Signaling",1.4823172807155491,0.6225586044537212,2.0,31.0,94.0,"CHP1,ARRB1",1.0,1.0]
["TR2","IPA","Ephrin B Signaling","Ephrin B Signaling",1.4768302712333532,0.6225608560353448,2.0,61.0,48.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","Erythropoietin Signaling","Erythropoietin Signaling",1.4768302712333532,0.6225608560353448,2.0,61.0,48.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","GM-CSF Signaling","GM-CSF Signaling",1.4768302712333532,0.6225608560353448,2.0,61.0,48.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","PEDF Signaling","PEDF Signaling",1.4768302712333532,0.6225608560353448,2.0,61.0,48.0,"HRAS,MAPK1",1.0,1.0]
["TR1","IPA","IL-15 Signaling","IL-15 Signaling",1.4767262572996191,0.6225608560353448,4.0,271.0,46.0,"AKT3,REL,JAK2,AXL",1.0,0.8734786605284558]
["TR26","IPA","α-Adrenergic Signaling","α-Adrenergic Signaling",1.474177200249807,0.624628157833755,3.0,120.0,60.0,"PRKCH,GNAS,GNG2",1.0,1.0]
["PR1","IPA","HMGB1 Signaling","HMGB1 Signaling",1.4737210485293077,1.0,6.0,83.0,32.0,"PIK3CA,TNFRSF1A,TNFRSF1B,ICAM1,SELE,VCAM1",1.0,0.8734786605284558]
["PR39","IPA","TNFR1 Signaling","TNFR1 Signaling",1.4731198566724966,1.0,1.0,5.0,9.0,"CASP2",1.0,1.0]
["PR16","IPA","Production of Nitric Oxide and Reactive Oxygen Species in Macrophages","Production of Nitric Oxide and Reactive Oxygen Species in Macrophages",1.472249616792911,1.0,8.0,98.0,42.0,"PIK3CG,RBP4,MAP3K7,TLR4,APOD,CLU,TYK2,IFNGR1",1.0,1.0]
["PR49","IPA","Hematopoiesis from Pluripotent Stem Cells","Hematopoiesis from Pluripotent Stem Cells",1.471907645054244,1.0,2.0,15.0,21.0,"IL12A,IL12B",1.0,1.0]
["PR34","h.all.v5.0.entrez","HALLMARK_ADIPOGENESIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ADIPOGENESIS",1.471689719437944,1.0,1.0,2.0,18.0,"APOE",0.974729731720942,1.0]
["TR22","IPA","RAR Activation","RAR Activation",1.4714982947728568,0.6254925117893171,22.0,1644.0,92.0,"PIK3CA,PRKCA,MAPK8,PRKD3,NFKB1,NFKB2,PDPK1,PRKAG1,PRKAR1B,SMARCA4,KAT2B,CSK,MAP3K1,TGFB1,VEGFA,SMAD2,SMAD4,NCOR2,SMAD9,SCAND1,TRIM24,RDH10",1.0,1.0]
["TR27","IPA","T Helper Cell Differentiation","T Helper Cell Differentiation",1.4713664886788487,0.6254925117893171,8.0,690.0,56.0,"IL18,IL5,HLA-DMA,HLA-DQA1,HLA-DQB1,HLA-DRB1,TRA,IL12RB1",1.0,1.0]
["PR25","h.all.v5.0.entrez","HALLMARK_DNA_REPAIR","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_DNA_REPAIR",1.471167509359724,1.0,2.0,40.0,8.0,"RAD51,TYMS",0.974729731720942,1.0]
["PR2","IPA","Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis","Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.468444999142271,1.0,3.0,12.0,66.0,"MMP1,DKK1,DKK4",1.0,1.0]
["TR4","IPA","Estrogen-Dependent Breast Cancer Signaling","Estrogen-Dependent Breast Cancer Signaling",1.467613343415632,0.628408921836971,2.0,76.0,39.0,"MAPK1,IGF1R",1.0,1.0]
["TR20","IPA","IL-17A Signaling in Airway Cells","IL-17A Signaling in Airway Cells",1.4665032143530783,0.628408921836971,2.0,69.0,43.0,"PIK3CB,REL",1.0,1.0]
["TR3","IPA","ErbB Signaling","ErbB Signaling",1.4653953759624536,0.628408921836971,2.0,54.0,55.0,"GSK3B,PIK3CB",1.0,1.0]
["TR23","h.all.v5.0.entrez","HALLMARK_UV_RESPONSE_UP","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UV_RESPONSE_UP",1.4640592189760102,0.6213070414626432,5.0,227.0,81.0,"SQSTM1,ENO2,CDK2,STIP1,CREG1",0.9831341072756744,1.0]
["TR23","IPA","Rac Signaling","Rac Signaling",1.4640592189760102,0.628408921836971,5.0,227.0,81.0,"PIP4K2B,ITGAV,ITGB7,IQGAP2,CYFIP2",1.0,1.0]
["TR22","IPA","PTEN Signaling","PTEN Signaling",1.4638695873250978,0.628408921836971,20.0,1644.0,82.0,"BAD,CDKN1B,KRAS,PIK3CA,YWHAH,MRAS,INPPL1,NFKB1,NFKB2,REL,PDPK1,ITGA2,ITGB8,PTK2,ITGA10,CASP3,TGFBR1,BCL2L11,ILK,MAST2",1.0,1.0]
["TR7","IPA","Gαi Signaling","Gαi Signaling",1.4625546747792033,0.6287386514032315,2.0,42.0,71.0,"GNB4,STAT3",1.0,1.0]
["TR2","IPA","Renal Cell Carcinoma Signaling","Renal Cell Carcinoma Signaling",1.4603797328694323,0.6298056936425704,2.0,61.0,49.0,"HRAS,MAPK1",1.0,1.0]
["PR47","IPA","Inhibition of Angiogenesis by TSP1","Inhibition of Angiogenesis by TSP1",1.4587391020181397,1.0,2.0,20.0,16.0,"CD36,KDR",1.0,1.0]
["TR5","IPA","Gαq Signaling","Gαq Signaling",1.4573210684921634,0.6298056936425704,2.0,31.0,97.0,"CHP1,BTK",1.0,1.0]
["TR9","IPA","IL-10 Signaling","IL-10 Signaling",1.4570137929655902,0.6298056936425704,4.0,269.0,47.0,"TNF,HMOX1,CCR5,IL10RA",1.0,1.0]
["TR32","IPA","Role of NFAT in Cardiac Hypertrophy","Role of NFAT in Cardiac Hypertrophy",1.4564232196280096,0.6298056936425704,3.0,62.0,118.0,"PIK3CA,HDAC8,MEF2A",1.0,1.0]
["TR32","IPA","mTOR Signaling","mTOR Signaling",1.4564232196280096,0.6298056936425704,3.0,62.0,118.0,"PIK3CA,PPP2CA,RPS6KA3",1.0,1.0]
["PR14","h.all.v5.0.entrez","HALLMARK_UV_RESPONSE_DN","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UV_RESPONSE_DN",1.4559577781311943,1.0,6.0,113.0,24.0,"ANXA2,BMPR1A,TGFBR3,IGF1R,MET,TFPI",0.9939409000468822,1.0]
["PR14","IPA","Coagulation System","Coagulation System",1.4559577781311943,1.0,6.0,113.0,24.0,"F2,FGA,PLG,F5,PLAU,TFPI",1.0,1.0]
["PR6","IPA","Germ Cell-Sertoli Cell Junction Signaling","Germ Cell-Sertoli Cell Junction Signaling",1.4542940600083103,1.0,5.0,78.0,26.0,"MAPK1,MAPK3,SRC,PDPK1,FER",1.0,1.0]
["PR6","IPA","HGF Signaling","HGF Signaling",1.4542940600083103,1.0,5.0,78.0,26.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PTPN11",1.0,1.0]
["PR4","IPA","Cellular Effects of Sildenafil (Viagra)","Cellular Effects of Sildenafil (Viagra)",1.4536892558432073,1.0,2.0,47.0,7.0,"PDIA3,PDE4D",1.0,1.0]
["PR4","IPA","tRNA Splicing","tRNA Splicing",1.4536892558432073,1.0,2.0,47.0,7.0,"PDE4D,PDE9A",1.0,1.0]
["PR2","IPA","Role of IL-17A in Arthritis","Role of IL-17A in Arthritis",1.451352925083768,1.0,2.0,12.0,27.0,"MMP1,CXCL6",1.0,1.0]
["PR2","IPA","Wnt/β-catenin Signaling","Wnt/β-catenin Signaling",1.451352925083768,1.0,2.0,12.0,27.0,"DKK1,DKK4",1.0,1.0]
["TR3","IPA","Ceramide Signaling","Ceramide Signaling",1.4510531861699407,0.6350923139607219,2.0,54.0,56.0,"PIK3CB,KSR1",1.0,1.0]
["PR46","IPA","Autoimmune Thyroid Disease Signaling","Autoimmune Thyroid Disease Signaling",1.44927504733486,1.0,4.0,108.0,13.0,"IL10,CD40LG,GZMB,TG",1.0,1.0]
["PR34","IPA","Reelin Signaling in Neurons","Reelin Signaling in Neurons",1.4484157757420764,1.0,1.0,2.0,19.0,"APOE",1.0,1.0]
["TR20","IPA","GDNF Family Ligand-Receptor Interactions","GDNF Family Ligand-Receptor Interactions",1.4481701771824365,0.6350923139607219,2.0,69.0,44.0,"KRAS,PIK3CB",1.0,1.0]
["PR21","IPA","Factors Promoting Cardiogenesis in Vertebrates","Factors Promoting Cardiogenesis in Vertebrates",1.447778798385049,1.0,2.0,13.0,25.0,"TGFBR2,BMP7",1.0,1.0]
["PR21","IPA","TGF-β Signaling","TGF-β Signaling",1.447778798385049,1.0,2.0,13.0,25.0,"TGFBR2,BMP7",1.0,1.0]
["PR10","IPA","VEGF Signaling","VEGF Signaling",1.447778798385049,1.0,2.0,13.0,25.0,"PLCG1,BCL2",1.0,1.0]
["TR29","IPA","Mouse Embryonic Stem Cell Pluripotency","Mouse Embryonic Stem Cell Pluripotency",1.4468233958607075,0.6350923139607219,3.0,121.0,61.0,"MYC,LEF1,FZD3",1.0,1.0]
["TR20","IPA","Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis","Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.4449213925377462,0.6350923139607219,4.0,69.0,184.0,"KRAS,PIK3CB,PPP3R1,CSNK1G1",1.0,1.0]
["TR2","IPA","CDK5 Signaling","CDK5 Signaling",1.444297916828907,0.6350923139607219,2.0,61.0,50.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","IL-3 Signaling","IL-3 Signaling",1.444297916828907,0.6350923139607219,2.0,61.0,50.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","Regulation of Cellular Mechanics by Calpain Protease","Regulation of Cellular Mechanics by Calpain Protease",1.444297916828907,0.6350923139607219,2.0,61.0,50.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","TGF-β Signaling","TGF-β Signaling",1.444297916828907,0.6350923139607219,2.0,61.0,50.0,"HRAS,MAPK1",1.0,1.0]
["TR23","IPA","Sertoli Cell-Sertoli Cell Junction Signaling","Sertoli Cell-Sertoli Cell Junction Signaling",1.4417305259099176,0.6356403934604808,6.0,227.0,110.0,"PRKAG2,ITGAV,ITGB7,SPTAN1,MAP3K13,SPTA1",1.0,1.0]
["TR5","IPA","PI3K Signaling in B Lymphocytes","PI3K Signaling in B Lymphocytes",1.4411259933436233,0.6356403934604808,2.0,31.0,99.0,"CHP1,BTK",1.0,1.0]
["TR13","IPA","Natural Killer Cell Signaling","Natural Killer Cell Signaling",1.4407800068826575,0.6356403934604808,4.0,172.0,74.0,"PRKCH,CD247,ZAP70,KLRD1",1.0,1.0]
["PR6","IPA","EGF Signaling","EGF Signaling",1.440509258082071,1.0,4.0,78.0,18.0,"MAPK1,MAPK3,SRC,CSNK2A1",1.0,1.0]
["PR6","IPA","NF-κB Activation by Viruses","NF-κB Activation by Viruses",1.440509258082071,1.0,4.0,78.0,18.0,"PRKCB,PRKCQ,MAPK1,MAPK3",1.0,1.0]
["PR6","IPA","Prostate Cancer Signaling","Prostate Cancer Signaling",1.440509258082071,1.0,4.0,78.0,18.0,"MAPK1,MAPK3,PDPK1,PA2G4",1.0,1.0]
["PR25","h.all.v5.0.entrez","HALLMARK_E2F_TARGETS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_E2F_TARGETS",1.4374026330196568,1.0,3.0,40.0,20.0,"AURKB,CHEK1,SYNCRIP",1.0,1.0]
["TR24","IPA","Role of NFAT in Cardiac Hypertrophy","Role of NFAT in Cardiac Hypertrophy",1.4371076594152017,0.6381400523433883,4.0,108.0,118.0,"GNG7,GNG11,PRKAR2B,CALM3",1.0,1.0]
["TR3","IPA","Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency","Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",1.436992539926172,0.6381400523433883,2.0,54.0,57.0,"GSK3B,PIK3CB",1.0,1.0]
["TR16","IPA","Renal Cell Carcinoma Signaling","Renal Cell Carcinoma Signaling",1.4349518060267727,0.6396155246441865,10.0,1114.0,49.0,"ATM,PIK3CD,PIK3R6,CREBBP,PAK2,SOS1,VEGFA,ETS1,TCEB1,CUL2",1.0,1.0]
["PR3","IPA","Hepatic Fibrosis / Hepatic Stellate Cell Activation","Hepatic Fibrosis / Hepatic Stellate Cell Activation",1.4346328666861308,1.0,3.0,12.0,68.0,"LBP,AGT,IGFBP4",1.0,1.0]
["PR35","h.all.v5.0.entrez","HALLMARK_APOPTOSIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_APOPTOSIS",1.4315827990372958,1.0,2.0,8.0,42.0,"CDKN1B,TNFRSF12A",1.0,1.0]
["TR20","IPA","Neurotrophin/TRK Signaling","Neurotrophin/TRK Signaling",1.4302955039880338,0.6430071896695362,2.0,69.0,45.0,"KRAS,PIK3CB",1.0,1.0]
["TR2","IPA","LPS-stimulated MAPK Signaling","LPS-stimulated MAPK Signaling",1.4285700380048012,0.6430071896695362,2.0,61.0,51.0,"HRAS,MAPK1",1.0,1.0]
["TR29","h.all.v5.0.entrez","HALLMARK_ESTROGEN_RESPONSE_LATE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ESTROGEN_RESPONSE_LATE",1.4284556508358095,0.6647539008451322,4.0,121.0,106.0,"FLNB,TIAM1,FAM102A,TJP3",1.0,1.0]
["PR52","IPA","Hypoxia Signaling in the Cardiovascular System","Hypoxia Signaling in the Cardiovascular System",1.4281833130276171,1.0,1.0,5.0,8.0,"P4HB",1.0,1.0]
["PR51","IPA","Mechanisms of Viral Exit from Host Cells","Mechanisms of Viral Exit from Host Cells",1.4281833130276171,1.0,1.0,5.0,8.0,"PRKCA",1.0,1.0]
["PR1","IPA","Extrinsic Prothrombin Activation Pathway","Extrinsic Prothrombin Activation Pathway",1.4278097925775253,1.0,3.0,83.0,10.0,"FGA,FGG,F3",1.0,0.9006287476986942]
["TR4","IPA","Thrombopoietin Signaling","Thrombopoietin Signaling",1.4277480569061867,0.6430071896695362,2.0,76.0,41.0,"MAPK1,IRS2",1.0,1.0]
["TR11","IPA","G-Protein Coupled Receptor Signaling","G-Protein Coupled Receptor Signaling",1.4265653169235828,0.6430071896695362,16.0,787.0,128.0,"PIK3CG,RAF1,DUSP1,GNAQ,PRKAR1A,CREB5,CAMK2G,PDE6C,MPPE1,FPR2,FPR1,HRH2,CXCR2,HCAR3,RGS14,RASGRP1",1.0,1.0]
["TR11","IPA","Acute Phase Response Signaling","Acute Phase Response Signaling",1.4261132919981214,0.6430071896695362,12.0,787.0,88.0,"FOS,PIK3CG,RAF1,MAP2K4,TNFRSF1A,TRAF6,CEBPB,IL1R1,IL1RAP,IL6R,SOD2,HAMP",1.0,1.0]
["TR20","IPA","Thrombin Signaling","Thrombin Signaling",1.425686090877351,0.6430071896695362,3.0,69.0,109.0,"KRAS,PIK3CB,REL",1.0,1.0]
["TR16","IPA","Protein Ubiquitination Pathway","Protein Ubiquitination Pathway",1.4254593972804332,0.6430071896695362,26.0,1114.0,166.0,"HSPA1A,HSPA5,HSPE1,DNAJB5,HSPB11,DNAJC17,BIRC3,PSMD14,TCEB1,CUL2,UBE2E1,UBE2H,UBE2J1,UBE2R2,UBE2Q1,PSMA1,PSMA3,PSMB1,PSMB7,PSMC2,AMFR,UCHL3,BAP1,USP6,USP25,USP45",1.0,1.0]
["TR15","pSS GWAS","nearby genes+cis eGenes","nearby genes+cis eGenes",1.424388956711036,0.9528009663204347,1.0,30.0,13.0,"HLA-DRA",1.0,1.0]
["PR46","IPA","FGF Signaling","FGF Signaling",1.423963425084868,1.0,8.0,108.0,39.0,"FGF4,FGF6,FGF12,FGF17,FGF16,RPS6KA5,FGFR2,FGFR4",1.0,1.0]
["PR16","IPA","cAMP-mediated signaling","cAMP-mediated signaling",1.4229002761538287,1.0,5.0,98.0,21.0,"PPP3R1,CAMK1,CAMK1D,PDE2A,PDE11A",1.0,1.0]
["PR3","h.all.v5.0.entrez","HALLMARK_GLYCOLYSIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_GLYCOLYSIS",1.4219105415296727,1.0,2.0,12.0,28.0,"ANGPTL4,IDUA",1.0,1.0]
["PR41","h.all.v5.0.entrez","HALLMARK_GLYCOLYSIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_GLYCOLYSIS",1.4219105415296727,1.0,2.0,12.0,28.0,"CHST2,CHST6",1.0,1.0]
["TR11","IPA","PPARα/RXRα Activation","PPARα/RXRα Activation",1.4198137831357358,0.6497350974380212,14.0,787.0,108.0,"PDIA3,RAF1,MAP2K4,CPT1B,FASN,GNAQ,PRKAR1A,TRAF6,STAT5B,IL1R1,IL1RAP,LPL,IL1R2,ACOX1",1.0,1.0]
["TR1","IPA","IL-6 Signaling","IL-6 Signaling",1.4170531053685604,0.6497350974380212,5.0,271.0,70.0,"AKT3,REL,IL1RN,JAK2,SOCS1",1.0,0.9006287476986942]
["TR11","IPA","TNFR1 Signaling","TNFR1 Signaling",1.4165708822799912,0.6497350974380212,6.0,787.0,33.0,"FOS,MAP2K4,TNFRSF1A,PAK2,APAF1,CASP6",1.0,1.0]
["PR23","IPA","Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis","Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.4150248318547791,1.0,3.0,10.0,94.0,"IL6,TLR2,IL1RL2",1.0,1.0]
["PR46","h.all.v5.0.entrez","HALLMARK_INFLAMMATORY_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INFLAMMATORY_RESPONSE",1.4149875241927106,1.0,11.0,108.0,61.0,"CCL20,PLAUR,IL1B,CCL2,INHBA,IL7R,CSF3R,LCK,IL10,VIP,IL18RAP",1.0,1.0]
["PR23","IPA","PPARα/RXRα Activation","PPARα/RXRα Activation",1.413687107948315,1.0,2.0,10.0,38.0,"IL6,IL1RL2",1.0,1.0]
["TR2","IPA","FLT3 Signaling in Hematopoietic Progenitor Cells","FLT3 Signaling in Hematopoietic Progenitor Cells",1.413182181411987,0.6497350974380212,2.0,61.0,52.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","JAK/Stat Signaling","JAK/Stat Signaling",1.413182181411987,0.6497350974380212,2.0,61.0,52.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","Melanocyte Development and Pigmentation Signaling","Melanocyte Development and Pigmentation Signaling",1.413182181411987,0.6497350974380212,2.0,61.0,52.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","Salvage Pathways of Pyrimidine Ribonucleotides","Salvage Pathways of Pyrimidine Ribonucleotides",1.413182181411987,0.6497350974380212,2.0,61.0,52.0,"MAPK1,HIPK1",1.0,1.0]
["TR20","IPA","IL-17 Signaling","IL-17 Signaling",1.4128587686577405,0.6497350974380212,2.0,69.0,46.0,"KRAS,PIK3CB",1.0,1.0]
["PR22","ADAMs","ADAMs","ADAMs",1.411453236812913,1.0,2.0,11.0,31.0,"LRP8,EREG",1.0,1.0]
["PR29","IPA","Communication between Innate and Adaptive Immune Cells","Communication between Innate and Adaptive Immune Cells",1.411453236812913,1.0,2.0,11.0,31.0,"IL8,CCL15",1.0,1.0]
["TR6","h.all.v5.0.entrez","HALLMARK_INTERFERON_ALPHA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_ALPHA_RESPONSE",1.4110829399281828,0.6744523641053894,2.0,35.0,91.0,"CASP1,TRIM25",1.0,1.0]
["TR27","IPA","CTLA4 Signaling in Cytotoxic T Lymphocytes","CTLA4 Signaling in Cytotoxic T Lymphocytes",1.4093636314012574,0.6534392263886732,9.0,690.0,68.0,"PIK3C2B,HLA-DMA,HLA-DQA1,HLA-DQB1,HLA-DRB1,TRA,AP2B1,CLTA,AP1S2",1.0,1.0]
["TR22","IPA","RANK Signaling in Osteoclasts","RANK Signaling in Osteoclasts",1.408393134144984,0.6534392263886732,16.0,1644.0,63.0,"ATM,PIK3C2A,PIK3CA,MAPK8,PPP3CA,NFKB1,NFKB2,REL,MAP2K7,MAP3K1,BIRC2,XIAP,MAP3K8,MAP3K9,TAB2,MITF",1.0,1.0]
["PR36","IPA","Cardiomyocyte Differentiation via BMP Receptors","Cardiomyocyte Differentiation via BMP Receptors",1.4074042908472992,1.0,1.0,7.0,6.0,"NPPB",1.0,1.0]
["TR22","IPA","CCR3 Signaling in Eosinophils","CCR3 Signaling in Eosinophils",1.40713448363004,0.6538361139713311,18.0,1644.0,73.0,"ATM,KRAS,PIK3C2A,PIK3CA,PRKCA,MRAS,PLCB1,PRKD3,PPP1R12A,PPP1CB,GNAI3,GNB1,GNG3,GNG2,GNB4,ROCK1,ROCK2,ITPR2",1.0,1.0]
["TR7","h.all.v5.0.entrez","HALLMARK_INTERFERON_GAMMA_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INTERFERON_GAMMA_RESPONSE",1.4062005399204045,0.6744523641053894,3.0,42.0,183.0,"STAT3,NMI,SPPL2A",1.0,1.0]
["TR18","IPA","Huntington's Disease Signaling","Huntington's Disease Signaling",1.4053333023655996,0.6540990955789409,42.0,2408.0,138.0,"ATM,PIK3C3,PIK3CG,PRKCB,PRKCI,MAPK9,PRKD3,ATF2,PDPK1,GNA15,GNG7,EP300,CREB1,SOS1,MAP2K7,HSPA1B,HSPA14,DNAJC5,CAPN7,APAF1,POLR2A,POLR2K,TAF9B,CASP2,CTSD,HDAC2,HDAC9,HDAC4,HDAC11,HDAC10,AP2A2,GLS,HIP1,NSF,ATP5J,STX16,NAPG,NAPA,YKT6,IFT57,NAPB,VTI1A",1.0,1.0]
["TR23","IPA","Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells","Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells",1.4049767564436693,0.6540990955789409,3.0,227.0,34.0,"HLA-A,BCL2,DFFA",1.0,1.0]
["TR32","IPA","FLT3 Signaling in Hematopoietic Progenitor Cells","FLT3 Signaling in Hematopoietic Progenitor Cells",1.4003361085903676,0.6545848254755632,2.0,62.0,52.0,"PIK3CA,RPS6KA3",1.0,1.0]
["TR32","IPA","Melanocyte Development and Pigmentation Signaling","Melanocyte Development and Pigmentation Signaling",1.4003361085903676,0.6545848254755632,2.0,62.0,52.0,"PIK3CA,RPS6KA3",1.0,1.0]
["TR3","h.all.v5.0.entrez","HALLMARK_G2M_CHECKPOINT","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_G2M_CHECKPOINT",1.3984633118987135,0.6744523641053894,3.0,54.0,143.0,"PTTG1,UBE2S,RPS6KA5",1.0,1.0]
["TR2","IPA","NF-κB Activation by Viruses","NF-κB Activation by Viruses",1.3981212352118595,0.6545848254755632,2.0,61.0,53.0,"HRAS,MAPK1",1.0,1.0]
["PR8","h.all.v5.0.entrez","HALLMARK_KRAS_SIGNALING_DN","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_KRAS_SIGNALING_DN",1.398113156928819,1.0,2.0,15.0,23.0,"CD207,SPHK2",1.0,1.0]
["PR6","h.all.v5.0.entrez","HALLMARK_ANDROGEN_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ANDROGEN_RESPONSE",1.3980586494579066,1.0,3.0,78.0,11.0,"RPS6KA3,UBE2I,PA2G4",1.0,1.0]
["PR6","IPA","Ephrin B Signaling","Ephrin B Signaling",1.3980586494579066,1.0,3.0,78.0,11.0,"MAPK1,MAPK3,ACP1",1.0,1.0]
["PR6","IPA","Estrogen Receptor Signaling","Estrogen Receptor Signaling",1.3980586494579066,1.0,3.0,78.0,11.0,"MAPK1,MAPK3,SRC",1.0,1.0]
["PR6","IPA","Estrogen-Dependent Breast Cancer Signaling","Estrogen-Dependent Breast Cancer Signaling",1.3980586494579066,1.0,3.0,78.0,11.0,"MAPK1,MAPK3,SRC",1.0,1.0]
["PR6","IPA","FcγRIIB Signaling in B Lymphocytes","FcγRIIB Signaling in B Lymphocytes",1.3980586494579066,1.0,3.0,78.0,11.0,"PDPK1,BTK,LYN",1.0,1.0]
["PR6","IPA","MIF-mediated Glucocorticoid Regulation","MIF-mediated Glucocorticoid Regulation",1.3980586494579066,1.0,3.0,78.0,11.0,"MAPK1,MAPK3,MIF",1.0,1.0]
["PR6","IPA","Semaphorin Signaling in Neurons","Semaphorin Signaling in Neurons",1.3980586494579066,1.0,3.0,78.0,11.0,"MAPK1,MAPK3,FYN",1.0,1.0]
["PR6","IPA","nNOS Signaling in Neurons","nNOS Signaling in Neurons",1.3980586494579066,1.0,3.0,78.0,11.0,"PRKCB,PRKCQ,CAMK2A",1.0,1.0]
["TR16","IPA","Growth Hormone Signaling","Growth Hormone Signaling",1.397730460709859,0.6545848254755632,9.0,1114.0,43.0,"ATM,PIK3CD,PLCG2,PRKD3,PIK3R6,IRS1,STAT3,SOCS2,RPS6KA2",1.0,1.0]
["TR16","IPA","IL-17A Signaling in Airway Cells","IL-17A Signaling in Airway Cells",1.397730460709859,0.6545848254755632,9.0,1114.0,43.0,"ATM,PIK3CD,PIK3R6,IKBKG,STAT3,JAK1,TYK2,CXCL5,CCL20",1.0,1.0]
["TR3","IPA","Acute Myeloid Leukemia Signaling","Acute Myeloid Leukemia Signaling",1.3964033694809461,0.6545848254755632,2.0,54.0,60.0,"PIK3CB,TCF3",1.0,1.0]
["TR20","IPA","BMP signaling pathway","BMP signaling pathway",1.3958408780077534,0.6545848254755632,2.0,69.0,47.0,"KRAS,REL",1.0,1.0]
["TR20","IPA","CD40 Signaling","CD40 Signaling",1.3958408780077534,0.6545848254755632,2.0,69.0,47.0,"PIK3CB,REL",1.0,1.0]
["TR20","IPA","Role of JAK1 and JAK3 in γc Cytokine Signaling","Role of JAK1 and JAK3 in γc Cytokine Signaling",1.3958408780077534,0.6545848254755632,2.0,69.0,47.0,"KRAS,PIK3CB",1.0,1.0]
["PR35","IPA","PTEN Signaling","PTEN Signaling",1.394019942555845,1.0,2.0,8.0,44.0,"CDKN1B,PTEN",1.0,1.0]
["TR28","IPA","Paxillin Signaling","Paxillin Signaling",1.3932306921324173,0.6570641800137935,4.0,213.0,62.0,"PIK3C2A,ITGAL,NCK1,NCK2",1.0,1.0]
["TR4","h.all.v5.0.entrez","HALLMARK_FATTY_ACID_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_FATTY_ACID_METABOLISM",1.3924836978800257,0.6744523641053894,3.0,76.0,102.0,"DHCR24,HSDL2,AOC3",1.0,1.0]
["TR14","h.all.v5.0.entrez","HALLMARK_ALLOGRAFT_REJECTION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ALLOGRAFT_REJECTION",1.3922020406476556,0.6744523641053894,5.0,120.0,160.0,"IRF8,CD40,HLA-DOA,CD79A,HLA-DOB",1.0,1.0]
["TR15","IPA","Dendritic Cell Maturation","Dendritic Cell Maturation",1.3912265815978653,0.6582747695670905,2.0,30.0,109.0,"HLA-DMB,HLA-DRA",1.0,1.0]
["PR6","IPA","Sertoli Cell-Sertoli Cell Junction Signaling","Sertoli Cell-Sertoli Cell Junction Signaling",1.3901637049502096,1.0,5.0,78.0,27.0,"MAPK1,MAPK3,SRC,PRKACA,EPB41",1.0,1.0]
["TR4","IPA","Growth Hormone Signaling","Growth Hormone Signaling",1.3899997447093912,0.6582747695670905,2.0,76.0,43.0,"MAPK1,IGF1R",1.0,1.0]
["TR27","IPA","OX40 Signaling Pathway","OX40 Signaling Pathway",1.3895391807879682,0.6582747695670905,6.0,690.0,38.0,"HLA-DMA,HLA-DPA1,HLA-DQA1,HLA-DQB1,HLA-DRB1,TRA",1.0,1.0]
["TR30","IPA","mTOR Signaling","mTOR Signaling",1.3879582836843363,0.6592169106407879,3.0,66.0,118.0,"PRKD3,PPP2R5D,PRKAA1",1.0,1.0]
["TR26","IPA","G Beta Gamma Signaling","G Beta Gamma Signaling",1.3863647742577407,0.6601827892182985,3.0,120.0,65.0,"PRKCH,GNAS,GNG2",1.0,1.0]
["PR29","IPA","HMGB1 Signaling","HMGB1 Signaling",1.3858964689179902,1.0,2.0,11.0,32.0,"MAPK12,IL8",1.0,1.0]
["PR42","IPA","IL-17 Signaling","IL-17 Signaling",1.3858964689179902,1.0,2.0,12.0,32.0,"MAPK8,IL17F",1.0,1.0]
["PR29","IPA","IL-17 Signaling","IL-17 Signaling",1.3858964689179902,1.0,2.0,11.0,32.0,"MAPK12,IL8",1.0,1.0]
["PR48","IPA","T Helper Cell Differentiation","T Helper Cell Differentiation",1.3858964689179902,1.0,2.0,11.0,32.0,"TGFB1,IL4R",1.0,1.0]
["PR14","IPA","Intrinsic Prothrombin Activation Pathway","Intrinsic Prothrombin Activation Pathway",1.3852046559274866,1.0,4.0,113.0,13.0,"F2,FGA,COL18A1,F5",1.0,1.0]
["TR9","IPA","Prostate Cancer Signaling","Prostate Cancer Signaling",1.3839299543123489,0.6624353109459984,5.0,269.0,72.0,"RRAS,MTOR,CREB1,SOS1,SOS2",1.0,1.0]
["TR17","IPA","IL-1 Signaling","IL-1 Signaling",1.3820935439683735,0.6637834785363603,7.0,531.0,62.0,"JUN,GNA12,MAP2K3,GNAS,GNB1,ECSIT,TOLLIP",1.0,1.0]
["PR25","IPA","Salvage Pathways of Pyrimidine Ribonucleotides","Salvage Pathways of Pyrimidine Ribonucleotides",1.3817962292876484,1.0,3.0,40.0,21.0,"PAK3,CDK5,CDK8",1.0,1.0]
["TR24","h.all.v5.0.entrez","HALLMARK_KRAS_SIGNALING_UP","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_KRAS_SIGNALING_UP",1.38127943974477,0.6825296985079133,4.0,108.0,123.0,"GUCY1A3,MMD,F13A1,GNG11",1.0,1.0]
["TR11","IPA","Hepatic Cholestasis","Hepatic Cholestasis",1.3803500684625123,0.6649952708235335,10.0,787.0,70.0,"PRKCQ,MAP2K4,TNFRSF1A,PRKAR1A,TRAF6,IL1R1,IL1RAP,TLR4,IL1R2,IRAK4",1.0,1.0]
["PR51","h.all.v5.0.entrez","HALLMARK_HEDGEHOG_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HEDGEHOG_SIGNALING",1.3778532922715503,1.0,1.0,5.0,9.0,"NRP1",1.0,1.0]
["TR32","IPA","Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis","Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.3764069101383634,0.6687756163514373,3.0,62.0,127.0,"PIK3CA,SMURF1,TAB2",1.0,1.0]
["TR3","IPA","Colorectal Cancer Metastasis Signaling","Colorectal Cancer Metastasis Signaling",1.375991709498472,0.6687756163514373,3.0,54.0,146.0,"GSK3B,PIK3CB,TCF3",1.0,1.0]
["PR12","h.all.v5.0.entrez","HALLMARK_INFLAMMATORY_RESPONSE","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_INFLAMMATORY_RESPONSE",1.3745090260052397,1.0,2.0,6.0,61.0,"CCL7,CCL22",1.0,1.0]
["TR24","ADAMs","ADAMs","ADAMs",1.3724768910788907,0.6786456842075087,2.0,108.0,31.0,"APP,EGF",1.0,1.0]
["PR23","IPA","IL-6 Signaling","IL-6 Signaling",1.3724130849898748,1.0,2.0,10.0,40.0,"IL6,IL1RL2",1.0,1.0]
["TR9","IPA","TGF-β Signaling","TGF-β Signaling",1.3723414679409953,0.6722433921468437,4.0,269.0,50.0,"RRAS,SOS1,SOS2,SMAD3",1.0,1.0]
["TR4","IPA","GDNF Family Ligand-Receptor Interactions","GDNF Family Ligand-Receptor Interactions",1.3718573579357325,0.6722433921468437,2.0,76.0,44.0,"MAPK1,IRS2",1.0,1.0]
["PR16","IPA","Calcium Signaling","Calcium Signaling",1.3711599810583204,1.0,4.0,98.0,15.0,"PPP3R1,HDAC8,CAMK1,CAMK1D",1.0,1.0]
["PR30","IPA","Salvage Pathways of Pyrimidine Ribonucleotides","Salvage Pathways of Pyrimidine Ribonucleotides",1.3699172946877092,1.0,2.0,17.0,21.0,"PIM1,PLK1",1.0,1.0]
["TR26","IPA","CCR5 Signaling in Macrophages","CCR5 Signaling in Macrophages",1.3697928450575132,0.6738644571965527,3.0,120.0,66.0,"PRKCH,GNAS,GNG2",1.0,1.0]
["TR2","IPA","ErbB Signaling","ErbB Signaling",1.3689312840747707,0.6738644571965527,2.0,61.0,55.0,"HRAS,MAPK1",1.0,1.0]
["PR16","IPA","iNOS Signaling","iNOS Signaling",1.3678968297617036,1.0,3.0,98.0,9.0,"TLR4,TYK2,IFNGR1",1.0,1.0]
["TR20","IPA","3-phosphoinositide Biosynthesis","3-phosphoinositide Biosynthesis",1.3675586405790163,0.674540770217606,3.0,69.0,115.0,"PIK3CB,INPP5B,PPP3R1",1.0,1.0]
["TR9","IPA","PKCθ Signaling in T Lymphocytes","PKCθ Signaling in T Lymphocytes",1.3651858357892521,0.6766608838901563,6.0,269.0,97.0,"RRAS,SOS1,SOS2,HLA-DQA1,TRB,MAP3K9",1.0,1.0]
["PR46","IPA","p38 MAPK Signaling","p38 MAPK Signaling",1.3648025691230297,1.0,7.0,108.0,33.0,"MAPT,IL1B,PLA2G5,PLA2G10,TGFB3,RPS6KA5,IL18RAP",1.0,1.0]
["PR49","IPA","PI3K/AKT Signaling","PI3K/AKT Signaling",1.3638757521618114,1.0,2.0,15.0,24.0,"PTGS2,NANOG",1.0,1.0]
["TR12","h.all.v5.0.entrez","HALLMARK_E2F_TARGETS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_E2F_TARGETS",1.3634451580842575,0.683709521352932,4.0,102.0,132.0,"SMC3,SYNCRIP,ATAD2,RAD1",1.0,1.0]
["TR20","IPA","HER-2 Signaling in Breast Cancer","HER-2 Signaling in Breast Cancer",1.3629912533115165,0.6766608838901563,2.0,69.0,49.0,"KRAS,PIK3CB",1.0,1.0]
["TR20","IPA","Renal Cell Carcinoma Signaling","Renal Cell Carcinoma Signaling",1.3629912533115165,0.6766608838901563,2.0,69.0,49.0,"KRAS,PIK3CB",1.0,1.0]
["TR1","IPA","IL-3 Signaling","IL-3 Signaling",1.3624679005383895,0.6766608838901563,4.0,271.0,50.0,"PRKCE,AKT3,STAT1,JAK2",1.0,0.9006287476986942]
["PR6","IPA","Reelin Signaling in Neurons","Reelin Signaling in Neurons",1.3619151525266424,1.0,4.0,78.0,19.0,"SRC,FYN,LYN,PAFAH1B2",1.0,1.0]
["PR48","IPA","p38 MAPK Signaling","p38 MAPK Signaling",1.361215999807203,1.0,2.0,11.0,33.0,"TGFB1,PLA2G2E",1.0,1.0]
["PR6","IPA","Role of Tissue Factor in Cancer","Role of Tissue Factor in Cancer",1.3610108272250103,1.0,7.0,78.0,46.0,"MAPK1,MAPK3,SRC,PTPN11,FYN,LYN,RPS6KA3",1.0,1.0]
["TR29","IPA","eNOS Signaling","eNOS Signaling",1.360848080028402,0.6777412238776853,3.0,121.0,66.0,"HSPA6,AQP3,NOSIP",1.0,1.0]
["TR18","h.all.v5.0.entrez","HALLMARK_OXIDATIVE_PHOSPHORYLATION","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_OXIDATIVE_PHOSPHORYLATION",1.357922408486246,0.683709521352932,42.0,2408.0,139.0,"RETSAT,ACADM,IDH1,NDUFA5,DLD,MRPL15,COX7B,UQCRQ,COX6A1,UQCR11,ATP6AP1,PDP1,CYB5A,PDK4,SUCLA2,UQCRB,NDUFS4,ATP5C1,ATP5J,NDUFB5,NDUFA4,COX7C,COX7A2,ATP6V1G1,ATP5F1,OPA1,ATP5I,MTX2,COX7A2L,TIMM17A,TIMM8B,ATP5L,NDUFB4,PDHX,MTRR,ACAT1,ATP6V0C,ACADSB,BDH2,MRPS22,MPC1,MTRF1",1.0,1.0]
["PR1","IPA","Acute Phase Response Signaling","Acute Phase Response Signaling",1.356572805231891,1.0,10.0,83.0,71.0,"PIK3CA,TNFRSF1A,C1QA,C1R,FGA,FGG,HNRNPK,IL6R,TNFRSF1B,VWF",1.0,0.9006287476986942]
["TR1","h.all.v5.0.entrez","HALLMARK_HYPOXIA","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_HYPOXIA",1.355775789432696,0.683709521352932,7.0,271.0,122.0,"ATF3,TNFAIP3,KDM3A,ISG20,NAGK,MT1E,MT2A",1.0,0.2915944874852224]
["TR28","IPA","Integrin Signaling","Integrin Signaling",1.3553678412503305,0.6843596025033452,6.0,213.0,123.0,"PIK3C2A,ITGAL,WASL,NCK1,NCK2,RAP1A",1.0,1.0]
["TR2","IPA","HIF1α Signaling","HIF1α Signaling",1.3547795528099664,0.6843596025033452,2.0,61.0,56.0,"HRAS,MAPK1",1.0,1.0]
["PR23","h.all.v5.0.entrez","HALLMARK_TNFA_SIGNALING_VIA_NFKB","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TNFA_SIGNALING_VIA_NFKB",1.35262675888235,1.0,2.0,10.0,41.0,"IL6,TLR2",1.0,1.0]
["TR21","h.all.v5.0.entrez","HALLMARK_KRAS_SIGNALING_UP","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_KRAS_SIGNALING_UP",1.3522753172758724,0.683709521352932,28.0,1685.0,123.0,"PLAUR,IL7R,ETS1,NIN,DOCK2,ANKH,MMP9,ITGB2,FUCA1,PRRX1,HSD11B1,CROT,TMEM176B,ABCB1,KIF5C,SDCCAG8,NAP1L2,ATG10,PDCD1LG2,KCNN4,TMEM176A,USP12,SLMO2,FBXO4,STRN,RBM4,CCSER2,GPNMB",1.0,1.0]
["TR16","IPA","Huntington's Disease Signaling","Huntington's Disease Signaling",1.3517204559303557,0.6867141389800782,22.0,1114.0,138.0,"ATM,PIK3CD,PRKD3,PIK3R6,GNA11,GNB2,GNB5,CREBBP,SOS1,HSPA1A,HSPA5,CASP7,CYCS,POLR2D,POLR2F,POLR2H,HDAC5,HDAC7,HDAC8,DNM1L,DYNC1I2,TCERG1",1.0,1.0]
["PR4","IPA","HIF1α Signaling","HIF1α Signaling",1.351367309270014,1.0,4.0,47.0,31.0,"MMP13,MMP10,MMP12,MMP16",1.0,1.0]
["TR1","IPA","Type I Diabetes Mellitus Signaling","Type I Diabetes Mellitus Signaling",1.3506809441309335,0.6867141389800782,5.0,271.0,73.0,"REL,STAT1,JAK2,MYD88,SOCS1",1.0,0.9006287476986942]
["TR11","h.all.v5.0.entrez","HALLMARK_CHOLESTEROL_HOMEOSTASIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_CHOLESTEROL_HOMEOSTASIS",1.3506635678432921,0.683709521352932,8.0,787.0,52.0,"NFIL3,PDK3,LPL,FASN,ACAT2,CXCL16,ANTXR2,FAM129A",1.0,1.0]
["PR19","IPA","Airway Pathology in Chronic Obstructive Pulmonary Disease","Airway Pathology in Chronic Obstructive Pulmonary Disease",1.3504397349997064,1.0,1.0,8.0,6.0,"MMP8",1.0,1.0]
["PR33","IPA","B Cell Development","B Cell Development",1.3504397349997064,1.0,1.0,8.0,6.0,"IGHD",1.0,1.0]
["PR18","IPA","Glycolysis I","Glycolysis I",1.3504397349997064,1.0,1.0,9.0,6.0,"GPI",1.0,1.0]
["PR35","IPA","TWEAK Signaling","TWEAK Signaling",1.3504397349997064,1.0,1.0,8.0,6.0,"TNFRSF12A",1.0,1.0]
["TR13","IPA","Chemokine Signaling","Chemokine Signaling",1.3503047501296328,0.6867141389800782,3.0,172.0,47.0,"MPRIP,CCL4,CCL5",1.0,1.0]
["PR39","IPA","4-1BB Signaling in T Lymphocytes","4-1BB Signaling in T Lymphocytes",1.3500339498324754,1.0,1.0,5.0,12.0,"TNFSF9",1.0,1.0]
["TR9","pSS GWAS","nearby genes+cis eGenes","nearby genes+cis eGenes",1.3493725044488447,0.9528009663204347,2.0,269.0,13.0,"HLA-DQA1,CUTA",1.0,1.0]
["TR20","IPA","Systemic Lupus Erythematosus Signaling","Systemic Lupus Erythematosus Signaling",1.3489995470267577,0.6867141389800782,3.0,69.0,117.0,"KRAS,PIK3CB,LSM14A",1.0,1.0]
["TR11","IPA","Melatonin Signaling","Melatonin Signaling",1.347763598155131,0.6867141389800782,7.0,787.0,43.0,"PDIA3,PRKCQ,RAF1,MAP2K4,GNAQ,PRKAR1A,CAMK2G",1.0,1.0]
["TR20","IPA","Macropinocytosis Signaling","Macropinocytosis Signaling",1.347127033502121,0.6867141389800782,2.0,69.0,50.0,"KRAS,PIK3CB",1.0,1.0]
["TR31","IPA","3-phosphoinositide Biosynthesis","3-phosphoinositide Biosynthesis",1.3468809393920709,0.6867141389800782,6.0,229.0,115.0,"SYNJ1,DUSP8,PTPN7,PTPN12,MTMR6,NUDT4",1.0,1.0]
["TR1","pSS GWAS","nearby genes+cis eGenes","nearby genes+cis eGenes",1.3435486261707004,0.9528009663204347,2.0,271.0,13.0,"GTF2I,TNFAIP3",1.0,0.0906737066246361]
["TR25","h.all.v5.0.entrez","HALLMARK_UV_RESPONSE_DN","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_UV_RESPONSE_DN",1.342122967925911,0.683709521352932,9.0,505.0,95.0,"MAPK14,SLC7A1,PTEN,AKT3,FYN,LAMC1,BCKDHB,SFMBT1,MTA1",1.0,1.0]
["TR32","IPA","Ceramide Signaling","Ceramide Signaling",1.3420420823117543,0.6868843023241233,2.0,62.0,56.0,"PIK3CA,PPP2CA",1.0,1.0]
["PR36","IPA","Polyamine Regulation in Colon Cancer","Polyamine Regulation in Colon Cancer",1.341689882206696,1.0,1.0,7.0,7.0,"PSME3",1.0,1.0]
["TR27","h.all.v5.0.entrez","HALLMARK_TGF_BETA_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TGF_BETA_SIGNALING",1.341523801116889,0.683709521352932,6.0,690.0,39.0,"BMPR2,SMAD1,FKBP1A,XIAP,CDK9,HDAC1",1.0,1.0]
["TR31","IPA","α-Adrenergic Signaling","α-Adrenergic Signaling",1.3409245261174683,0.6868843023241233,4.0,229.0,60.0,"GNA12,GNA13,GNG10,CALM1",1.0,1.0]
["TR2","IPA","PPAR Signaling","PPAR Signaling",1.3409091837001514,0.6868843023241233,2.0,61.0,57.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency","Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",1.3409091837001514,0.6868843023241233,2.0,61.0,57.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","VEGF Signaling","VEGF Signaling",1.3409091837001514,0.6868843023241233,2.0,61.0,57.0,"HRAS,MAPK1",1.0,1.0]
["TR19","IPA","Huntington's Disease Signaling","Huntington's Disease Signaling",1.3406934042362473,0.6868843023241233,3.0,59.0,138.0,"RASA1,CYCS,NAPB",1.0,1.0]
["TR20","IPA","Role of NFAT in Cardiac Hypertrophy","Role of NFAT in Cardiac Hypertrophy",1.3398651525836942,0.6868843023241233,3.0,69.0,118.0,"KRAS,PIK3CB,PPP3R1",1.0,1.0]
["TR7","IPA","Pancreatic Adenocarcinoma Signaling","Pancreatic Adenocarcinoma Signaling",1.3394122204862966,0.6868843023241233,2.0,42.0,83.0,"STAT3,SIN3A",1.0,1.0]
["TR8","IPA","PI3K/AKT Signaling","PI3K/AKT Signaling",1.3386722727429938,0.6868843023241233,2.0,36.0,97.0,"NFKBIE,CDKN1A",1.0,1.0]
["PR29","IPA","Hepatic Cholestasis","Hepatic Cholestasis",1.3373586532424158,1.0,2.0,11.0,34.0,"MAPK12,IL8",1.0,1.0]
["TR4","IPA","IL-15 Signaling","IL-15 Signaling",1.3369265481087327,0.6882376947212069,2.0,76.0,46.0,"MAPK1,IL15RA",1.0,1.0]
["PR1","IPA","CD40 Signaling","CD40 Signaling",1.3360476162929213,1.0,4.0,83.0,18.0,"PIK3CA,LTA,ICAM1,FCER2",1.0,0.9006287476986942]
["PR31","h.all.v5.0.entrez","HALLMARK_APOPTOSIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_APOPTOSIS",1.3333705769467223,1.0,2.0,9.0,42.0,"TNF,HGF",1.0,1.0]
["PR50","IPA","IL-8 Signaling","IL-8 Signaling",1.3333705769467223,1.0,2.0,9.0,42.0,"PROK1,CXCL1",1.0,1.0]
["TR13","h.all.v5.0.entrez","HALLMARK_XENOBIOTIC_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_XENOBIOTIC_METABOLISM",1.3326318033846136,0.683709521352932,5.0,172.0,116.0,"ID2,ATP2A2,ABHD6,NPC1,AP4B1",1.0,1.0]
["TR23","h.all.v5.0.entrez","HALLMARK_GLYCOLYSIS","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_GLYCOLYSIS",1.3319240316960266,0.683709521352932,6.0,227.0,117.0,"ENO2,ENO1,CITED2,SAP30,TGFBI,GOT2",1.0,1.0]
["TR20","IPA","Antioxidant Action of Vitamin C","Antioxidant Action of Vitamin C",1.3316165133707527,0.695015192953988,2.0,69.0,51.0,"REL,SLC23A3",1.0,1.0]
["TR24","IPA","SAPK/JNK Signaling","SAPK/JNK Signaling",1.3308944469694126,0.695015192953988,3.0,108.0,76.0,"GNG7,GNG11,TRB",1.0,1.0]
["PR6","IPA","Ovarian Cancer Signaling","Ovarian Cancer Signaling",1.3295032531881017,1.0,5.0,78.0,28.0,"MAPK1,MAPK3,SRC,PRKACA,PA2G4",1.0,1.0]
["PR6","IPA","Type II Diabetes Mellitus Signaling","Type II Diabetes Mellitus Signaling",1.3295032531881017,1.0,5.0,78.0,28.0,"PRKCB,PRKCQ,MAPK1,MAPK3,PDPK1",1.0,1.0]
["TR28","IPA","Clathrin-mediated Endocytosis Signaling","Clathrin-mediated Endocytosis Signaling",1.3287555989534772,0.6951005015807783,5.0,213.0,94.0,"PIK3C2A,PPP3CB,PPP3R1,WASL,CLTC",1.0,1.0]
["TR22","IPA","B Cell Receptor Signaling","B Cell Receptor Signaling",1.328483964426915,0.6951005015807783,26.0,1644.0,116.0,"ATM,BAD,KRAS,PIK3C2A,PIK3CA,MAPK8,MRAS,INPPL1,PPP3CA,PTPN11,PTPRC,NFKB1,NFKB2,REL,PDPK1,ABL1,CSK,VAV3,MAP2K7,MAP3K1,BCL2A1,MAP3K8,EGR1,FCGR2A,MAP3K9,POU2F2",1.0,1.0]
["TR2","IPA","PDGF Signaling","PDGF Signaling",1.3273102745024026,0.6951005015807783,2.0,61.0,58.0,"HRAS,MAPK1",1.0,1.0]
["TR2","IPA","Prolactin Signaling","Prolactin Signaling",1.3273102745024026,0.6951005015807783,2.0,61.0,58.0,"HRAS,MAPK1",1.0,1.0]
["PR15","h.all.v5.0.entrez","HALLMARK_XENOBIOTIC_METABOLISM","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_XENOBIOTIC_METABOLISM",1.3266008326855023,1.0,2.0,10.0,38.0,"NMT1,ARG1",1.0,1.0]
["PR7","IPA","Human Embryonic Stem Cell Pluripotency","Human Embryonic Stem Cell Pluripotency",1.3264602077804302,1.0,4.0,39.0,38.0,"TGFB2,NTF4,WNT7A,FGFR3",1.0,1.0]
["PR35","IPA","Clathrin-mediated Endocytosis Signaling","Clathrin-mediated Endocytosis Signaling",1.3242560482079027,1.0,2.0,8.0,48.0,"FGF2,PGF",1.0,1.0]
["TR5","h.all.v5.0.entrez","HALLMARK_ESTROGEN_RESPONSE_EARLY","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_ESTROGEN_RESPONSE_EARLY",1.323348925320047,0.6892348183899888,2.0,31.0,115.0,"BHLHE40,ELF1",1.0,1.0]
["TR9","IPA","Graft-versus-Host Disease Signaling","Graft-versus-Host Disease Signaling",1.3231672168491249,0.6971844139960591,3.0,269.0,31.0,"TNF,HLA-DQA1,TRB",1.0,1.0]
["TR22","IPA","Antiproliferative Role of Somatostatin Receptor 2","Antiproliferative Role of Somatostatin Receptor 2",1.3231059915351902,0.6971844139960591,11.0,1644.0,40.0,"ATM,CDKN1B,KRAS,PIK3C2A,PIK3CA,MRAS,PTPN11,GNB1,GNG3,GNG2,GNB4",1.0,1.0]
["TR8","IPA","PI3K Signaling in B Lymphocytes","PI3K Signaling in B Lymphocytes",1.322749352944303,0.6971844139960591,2.0,36.0,99.0,"NFKBIE,ATF5",1.0,1.0]
["TR9","IPA","NGF Signaling","NGF Signaling",1.3199436240287505,0.6971844139960591,5.0,269.0,75.0,"RRAS,CREB1,SOS1,SOS2,MAP3K9",1.0,1.0]
["TR9","IPA","JAK/Stat Signaling","JAK/Stat Signaling",1.3196017286990553,0.6971844139960591,4.0,269.0,52.0,"RRAS,MTOR,SOS1,SOS2",1.0,1.0]
["TR9","IPA","Melanocyte Development and Pigmentation Signaling","Melanocyte Development and Pigmentation Signaling",1.3196017286990553,0.6971844139960591,4.0,269.0,52.0,"RRAS,CREB1,SOS1,SOS2",1.0,1.0]
["TR18","IPA","Role of BRCA1 in DNA Damage Response","Role of BRCA1 in DNA Damage Response",1.3184400906833995,0.6971844139960591,16.0,2408.0,45.0,"ATM,HLTF,CHEK1,FANCD2,RAD50,RB1,BRCC3,ATF1,MSH2,POU2F1,FANCA,RFC3,C19orf40,RBBP8,BRIP1,FAM175A",1.0,1.0]
["TR24","IPA","Glioma Signaling","Glioma Signaling",1.3168879926049055,0.6971844139960591,3.0,108.0,77.0,"EGF,PDGFA,CALM3",1.0,1.0]
["TR20","IPA","FLT3 Signaling in Hematopoietic Progenitor Cells","FLT3 Signaling in Hematopoietic Progenitor Cells",1.3164457775864158,0.6971844139960591,2.0,69.0,52.0,"KRAS,PIK3CB",1.0,1.0]
["TR20","IPA","JAK/Stat Signaling","JAK/Stat Signaling",1.3164457775864158,0.6971844139960591,2.0,69.0,52.0,"KRAS,PIK3CB",1.0,1.0]
["TR20","IPA","Melanocyte Development and Pigmentation Signaling","Melanocyte Development and Pigmentation Signaling",1.3164457775864158,0.6971844139960591,2.0,69.0,52.0,"KRAS,PIK3CB",1.0,1.0]
["PR45","IPA","Autoimmune Thyroid Disease Signaling","Autoimmune Thyroid Disease Signaling",1.315889641659991,1.0,1.0,4.0,13.0,"CGA",1.0,1.0]
["PR28","IPA","Ephrin A Signaling","Ephrin A Signaling",1.315889641659991,1.0,1.0,4.0,13.0,"EPHA5",1.0,1.0]
["TR1","IPA","Role of PKR in Interferon Induction and Antiviral Response","Role of PKR in Interferon Induction and Antiviral Response",1.3152378496329507,0.6977445594732987,3.0,271.0,31.0,"REL,STAT1,EIF2AK2",1.0,0.9006287476986942]
["PR3","IPA","Renin-Angiotensin Signaling","Renin-Angiotensin Signaling",1.314885522197936,1.0,2.0,12.0,32.0,"MAPK11,AGT",1.0,1.0]
["PR1","IPA","Ephrin B Signaling","Ephrin B Signaling",1.3142995069434245,1.0,3.0,83.0,11.0,"HNRNPK,EPHB2,EPHB6",1.0,0.9006287476986942]
["PR48","IPA","Pancreatic Adenocarcinoma Signaling","Pancreatic Adenocarcinoma Signaling",1.314275950129673,1.0,2.0,11.0,35.0,"CDK2,TGFB1",1.0,1.0]
["PR27","IPA","Leukocyte Extravasation Signaling","Leukocyte Extravasation Signaling",1.312031114231986,1.0,4.0,30.0,50.0,"PRKCD,MMP7,MMP14,JAM3",1.0,1.0]
["PR16","IPA","LXR/RXR Activation","LXR/RXR Activation",1.3119123927933285,1.0,8.0,98.0,45.0,"AHSG,SERPINF2,RBP4,IL37,TLR4,APOD,CLU,IL1RAPL2",1.0,1.0]
["TR3","h.all.v5.0.entrez","HALLMARK_TNFA_SIGNALING_VIA_NFKB","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_TNFA_SIGNALING_VIA_NFKB",1.311816776001454,0.6946648391273927,3.0,54.0,155.0,"TNFRSF9,SGK1,PHLDA2",1.0,1.0]
["TR23","h.all.v5.0.entrez","HALLMARK_MTORC1_SIGNALING","http://www.broadinstitute.org/gsea/msigdb/cards/HALLMARK_MTORC1_SIGNALING",1.3099565958382193,0.6946648391273927,7.0,227.0,149.0,"SQSTM1,GPI,ENO1,ACLY,FADS1,ACACA,STIP1",1.0,1.0]
["PR35","IPA","Colorectal Cancer Metastasis Signaling","Colorectal Cancer Metastasis Signaling",1.3078221267976708,1.0,2.0,8.0,49.0,"PGF,MMP3",1.0,1.0]
["PR7","IPA","Aryl Hydrocarbon Receptor Signaling","Aryl Hydrocarbon Receptor Signaling",1.3077716588092285,1.0,3.0,39.0,23.0,"CHEK2,IL1A,TGFB2",1.0,1.0]
["PR7","IPA","IL-15 Signaling","IL-15 Signaling",1.3077716588092285,1.0,3.0,39.0,23.0,"KRAS,IL4,IL15RA",1.0,1.0]
["TR26","IPA","RhoA Signaling","RhoA Signaling",1.3064777827018488,0.7058371755359777,3.0,120.0,70.0,"PIP4K2A,KTN1,SEPT2",1.0,1.0]
["PR7","IPA","Cell Cycle: G2/M DNA Damage Checkpoint Regulation","Cell Cycle: G2/M DNA Damage Checkpoint Regulation",1.3059403075891394,1.0,2.0,39.0,10.0,"CHEK2,CCNB1",1.0,1.0]
["TR5","IPA","Role of NFAT in Cardiac Hypertrophy","Role of NFAT in Cardiac Hypertrophy",1.303310288437031,0.7058371755359777,2.0,31.0,118.0,"CHP1,MEF2A",1.0,1.0]
["TR13","IPA","fMLP Signaling in Neutrophils","fMLP Signaling in Neutrophils",1.3032114893880824,0.7058371755359777,4.0,172.0,82.0,"PRKCH,PPP3CC,ARPC5L,NFATC2",1.0,1.0]
["TR25","IPA","Hereditary Breast Cancer Signaling","Hereditary Breast Cancer Signaling",1.3031763982855487,0.7058371755359777,8.0,505.0,82.0,"ATM,AKT3,PTEN,CCND2,CDK4,RPA1,FANCC,RFC1",1.0,1.0]
["TR24","IPA","Epithelial Adherens Junction Signaling","Epithelial Adherens Junction Signaling",1.303105438611302,0.7058371755359777,3.0,108.0,78.0,"TUBB1,EGF,VCL",1.0,1.0]
["TR16","IPA","Lymphotoxin β Receptor Signaling","Lymphotoxin β Receptor Signaling",1.3029462979486617,0.7058371755359777,8.0,1114.0,38.0,"ATM,PIK3CD,PIK3R6,IKBKG,CREBBP,TRAF3,CYCS,LTBR",1.0,1.0]
["PR27","IPA","3-phosphoinositide Degradation","3-phosphoinositide Degradation",1.3014654751449515,1.0,2.0,30.0,13.0,"PTPN2,PDXP",1.0,1.0]
["PR38","IPA","Crosstalk between Dendritic Cells and Natural Killer Cells","Crosstalk between Dendritic Cells and Natural Killer Cells",1.3014654751449515,1.0,2.0,13.0,30.0,"LTA,CSF2",1.0,1.0]
["PR27","IPA","D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis","D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis",1.3014654751449515,1.0,2.0,30.0,13.0,"PTPN2,PDXP",1.0,1.0]
["PR27","IPA","D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis","D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis",1.3014654751449515,1.0,2.0,30.0,13.0,"PTPN2,PDXP",1.0,1.0]
["PR27","IPA","Nitric Oxide Signaling in the Cardiovascular System","Nitric Oxide Signaling in the Cardiovascular System",1.3014654751449515,1.0,2.0,30.0,13.0,"PRKCD,VEGFC",1.0,1.0]
["TR32","IPA","Cyclins and Cell Cycle Regulation","Cyclins and Cell Cycle Regulation",1.3013171221044362,0.7058371755359777,2.0,62.0,59.0,"PPP2CA,HDAC8",1.0,1.0]